LOCUS       DAEPXW010000001        90415 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.001, whole genome shotgun sequence.
ACCESSION   DAEPXW010000001 DAEPXW010000000
VERSION     DAEPXW010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 90415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90415
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.001"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(301..1182)
                     /locus_tag="KRM55_000001"
     CDS             complement(301..1182)
                     /locus_tag="KRM55_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBH1592280.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            1638..2612
                     /locus_tag="KRM55_000002"
     CDS             1638..2612
                     /locus_tag="KRM55_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592281.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     ISMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(2728..3789)
                     /locus_tag="KRM55_000003"
     CDS             complement(2728..3789)
                     /locus_tag="KRM55_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1592282.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVANFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(4401..5252)
                     /locus_tag="KRM55_000004"
     CDS             complement(4401..5252)
                     /locus_tag="KRM55_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1592283.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(5269..6189)
                     /locus_tag="KRM55_000005"
     CDS             complement(5269..6189)
                     /locus_tag="KRM55_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HBH1592284.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(6299..7213)
                     /gene="murQ"
                     /locus_tag="KRM55_000006"
     CDS             complement(6299..7213)
                     /gene="murQ"
                     /locus_tag="KRM55_000006"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBH1592285.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(7312..8409)
                     /locus_tag="KRM55_000007"
     CDS             complement(7312..8409)
                     /locus_tag="KRM55_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH1592286.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLNFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLKH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(8623..9969)
                     /locus_tag="KRM55_000008"
     CDS             complement(8623..9969)
                     /locus_tag="KRM55_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1592287.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(10058..10366)
                     /locus_tag="KRM55_000009"
     CDS             complement(10058..10366)
                     /locus_tag="KRM55_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1592288.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(10628..11026)
                     /locus_tag="KRM55_000010"
     CDS             complement(10628..11026)
                     /locus_tag="KRM55_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592289.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIRNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(11028..12188)
                     /locus_tag="KRM55_000011"
     CDS             complement(11028..12188)
                     /locus_tag="KRM55_000011"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBH1592290.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISENGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(12619..13638)
                     /locus_tag="KRM55_000012"
     CDS             complement(12619..13638)
                     /locus_tag="KRM55_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1592291.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(13632..14312)
                     /locus_tag="KRM55_000013"
     CDS             complement(13632..14312)
                     /locus_tag="KRM55_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1592292.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(14464..16371)
                     /locus_tag="KRM55_000014"
     CDS             complement(14464..16371)
                     /locus_tag="KRM55_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1592293.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNVYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(16372..17124)
                     /locus_tag="KRM55_000015"
     CDS             complement(16372..17124)
                     /locus_tag="KRM55_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1592294.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(17440..18594)
                     /locus_tag="KRM55_000016"
     CDS             complement(17440..18594)
                     /locus_tag="KRM55_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1592295.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(18597..19064)
                     /locus_tag="KRM55_000017"
     CDS             complement(18597..19064)
                     /locus_tag="KRM55_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1592296.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(19078..19566)
                     /locus_tag="KRM55_000018"
     CDS             complement(19078..19566)
                     /locus_tag="KRM55_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592297.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     II"
     gene            complement(19580..20911)
                     /locus_tag="KRM55_000019"
     CDS             complement(19580..20911)
                     /locus_tag="KRM55_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1592298.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     DRQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKNMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(20925..22490)
                     /locus_tag="KRM55_000020"
     CDS             complement(20925..22490)
                     /locus_tag="KRM55_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1592299.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(22660..23445)
                     /locus_tag="KRM55_000021"
     CDS             complement(22660..23445)
                     /locus_tag="KRM55_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1592300.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(23612..24811)
                     /locus_tag="KRM55_000022"
     CDS             complement(23612..24811)
                     /locus_tag="KRM55_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBH1592301.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(25333..26670)
                     /gene="xylA"
                     /locus_tag="KRM55_000023"
     CDS             complement(25333..26670)
                     /gene="xylA"
                     /locus_tag="KRM55_000023"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBH1592302.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRNLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(26766..28316)
                     /gene="xylB"
                     /locus_tag="KRM55_000024"
     CDS             complement(26766..28316)
                     /gene="xylB"
                     /locus_tag="KRM55_000024"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBH1592303.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDNFKLLDE
                     VVNAKINN"
     gene            28524..29684
                     /locus_tag="KRM55_000025"
     CDS             28524..29684
                     /locus_tag="KRM55_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH1592304.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKIIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(29840..30244)
                     /locus_tag="KRM55_000026"
     CDS             complement(29840..30244)
                     /locus_tag="KRM55_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1592305.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(30265..30747)
                     /locus_tag="KRM55_000027"
     CDS             complement(30265..30747)
                     /locus_tag="KRM55_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1592306.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(30767..31576)
                     /locus_tag="KRM55_000028"
     CDS             complement(30767..31576)
                     /locus_tag="KRM55_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1592307.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(31569..32348)
                     /locus_tag="KRM55_000029"
     CDS             complement(31569..32348)
                     /locus_tag="KRM55_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1592308.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(32348..34426)
                     /locus_tag="KRM55_000030"
     CDS             complement(32348..34426)
                     /locus_tag="KRM55_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBH1592309.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(35225..35746)
                     /locus_tag="KRM55_000031"
     CDS             complement(35225..35746)
                     /locus_tag="KRM55_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH1592310.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKIKDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            35912..36478
                     /locus_tag="KRM55_000032"
     CDS             35912..36478
                     /locus_tag="KRM55_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1592311.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(36695..38758)
                     /locus_tag="KRM55_000033"
     CDS             complement(36695..38758)
                     /locus_tag="KRM55_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HBH1592312.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(39139..42474)
                     /locus_tag="KRM55_000034"
     CDS             complement(39139..42474)
                     /locus_tag="KRM55_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH1592313.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYTNDSDLLLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTANYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIWEEIEVQGMSNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLTSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKTETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRKLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(42524..42952)
                     /locus_tag="KRM55_000035"
     CDS             complement(42524..42952)
                     /locus_tag="KRM55_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592314.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDHLLTCEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(42942..43322)
                     /locus_tag="KRM55_000036"
     CDS             complement(42942..43322)
                     /locus_tag="KRM55_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBH1592315.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTKALRNILDIDVDLKIVTDNYTIALKKAILEGKVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(43355..43663)
                     /locus_tag="KRM55_000037"
     CDS             complement(43355..43663)
                     /locus_tag="KRM55_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592316.1"
                     /translation="MNQIELDLYHDMVNIYKEADLQCNYKLTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(43696..44796)
                     /locus_tag="KRM55_000038"
     CDS             complement(43696..44796)
                     /locus_tag="KRM55_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBH1592317.1"
                     /translation="MEYIKLNELCYINIGKTPSRNTSDYWGSGNRWLSISDLKEKYIS
                     KSKEEITDLAVEKANMKLVPKNTVVMSFKLSIGRVAILKEDMFTNEAIANFQIKNNEL
                     ITSEYLYYALRTLNFNNTDRAVMGATLNKSKLNDIKIPYFTICIQNKMVKVLNKAQEL
                     INKRKEQIEALDELVKSRFIEMFGNVITNSKDWDTELLGEISNLKAGKNIKAKDIYEK
                     NSHELYPCYGGNGLRGYVKMYSHKGTFNLIGRQGALCGNVKYVNGKFYATEHAVVVQP
                     KVDINSYWLYFTLKELDLNRLSTGAAQPGLTVGKLNEVEIPKVPVYLQNKFVDFVRQI
                     DKLKSRMEDSLKELENNFNSLMQKAFKGELFN"
     gene            complement(44800..46263)
                     /locus_tag="KRM55_000039"
     CDS             complement(44800..46263)
                     /locus_tag="KRM55_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBH1592318.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIAVGLEELERMLEV"
     gene            complement(46773..47642)
                     /gene="gatY"
                     /locus_tag="KRM55_000040"
     CDS             complement(46773..47642)
                     /gene="gatY"
                     /locus_tag="KRM55_000040"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH1592319.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(47662..49578)
                     /locus_tag="KRM55_000041"
     CDS             complement(47662..49578)
                     /locus_tag="KRM55_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBH1592320.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGSLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKKGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(49581..50501)
                     /locus_tag="KRM55_000042"
     CDS             complement(49581..50501)
                     /locus_tag="KRM55_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBH1592321.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(50603..51355)
                     /locus_tag="KRM55_000043"
     CDS             complement(50603..51355)
                     /locus_tag="KRM55_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1592322.1"
                     /translation="MIIEINKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(51747..53192)
                     /locus_tag="KRM55_000044"
     CDS             complement(51747..53192)
                     /locus_tag="KRM55_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1592323.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDKNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEEARYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKKRYKKDSFYWYQNLIRTNGEELKEK"
     gene            complement(53214..53567)
                     /locus_tag="KRM55_000045"
     CDS             complement(53214..53567)
                     /locus_tag="KRM55_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1592324.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(53596..54843)
                     /locus_tag="KRM55_000046"
     CDS             complement(53596..54843)
                     /locus_tag="KRM55_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1592325.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(54851..55168)
                     /locus_tag="KRM55_000047"
     CDS             complement(54851..55168)
                     /locus_tag="KRM55_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1592326.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            55410..57323
                     /locus_tag="KRM55_000048"
     CDS             55410..57323
                     /locus_tag="KRM55_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1592327.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNFQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IDSVEVVNYIDNNVDINIAKDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYNQM
                     DTKSLSNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(57446..58600)
                     /locus_tag="KRM55_000049"
     CDS             complement(57446..58600)
                     /locus_tag="KRM55_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBH1592328.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDKNNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(58880..61495)
                     /gene="mngB"
                     /locus_tag="KRM55_000050"
     CDS             complement(58880..61495)
                     /gene="mngB"
                     /locus_tag="KRM55_000050"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH1592329.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHHEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVNAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEIGHMLEKAYEVCDMVDNDFYTIQINENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKIAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(61624..63564)
                     /gene="mngA"
                     /locus_tag="KRM55_000051"
     CDS             complement(61624..63564)
                     /gene="mngA"
                     /locus_tag="KRM55_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBH1592330.1"
                     /translation="MEFKKITNENLVFLKQKIKTKKDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEASFAAMTLETPIENWESVDPNNKVELI
                     FLIAVPENKGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIVLAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIHKKIRY"
     gene            complement(63694..64419)
                     /locus_tag="KRM55_000052"
     CDS             complement(63694..64419)
                     /locus_tag="KRM55_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1592331.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(64682..65452)
                     /locus_tag="KRM55_000053"
     CDS             complement(64682..65452)
                     /locus_tag="KRM55_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBH1592332.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(65454..66881)
                     /locus_tag="KRM55_000054"
     CDS             complement(65454..66881)
                     /locus_tag="KRM55_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1592333.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            67272..67994
                     /locus_tag="KRM55_000055"
     CDS             67272..67994
                     /locus_tag="KRM55_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1592334.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            68191..69858
                     /locus_tag="KRM55_000056"
     CDS             68191..69858
                     /locus_tag="KRM55_000056"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBH1592335.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMNDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(69954..71273)
                     /locus_tag="KRM55_000057"
     CDS             complement(69954..71273)
                     /locus_tag="KRM55_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1592336.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYADKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVDVK"
     gene            complement(71314..72060)
                     /locus_tag="KRM55_000058"
     CDS             complement(71314..72060)
                     /locus_tag="KRM55_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH1592337.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVIEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(72304..74313)
                     /locus_tag="KRM55_000059"
     CDS             complement(72304..74313)
                     /locus_tag="KRM55_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1592338.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNVKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLRHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSING
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(74751..76184)
                     /locus_tag="KRM55_000060"
     CDS             complement(74751..76184)
                     /locus_tag="KRM55_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1592339.1"
                     /translation="MSFKKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKVVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(76200..77624)
                     /gene="ascB"
                     /locus_tag="KRM55_000061"
     CDS             complement(76200..77624)
                     /gene="ascB"
                     /locus_tag="KRM55_000061"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1592340.1"
                     /translation="MALRKDFLWGGATAANQCEGGYKEDGRGLANVDVTPQGKDRFPV
                     LAGKMKMFECDDEHYYPAHEAIDMYHNYKEDIKLFAEMGFKCYRMSIAWTRIFPTGVE
                     DVPNEEGLKFYEDLFDECLKYGIEPVVTICHFDVPMYLVKKYGAWRNRKLVDLYVKYC
                     EVIFTRFKGKVKYWLTFNEINMILHLPFIGAGLYIEEGENEEQIKYQAAHHQLVASAL
                     VTKLAHNINQEFKIGCMLAAGNTYPNTCNPLDVWKSIEKDRENYFFIDVQSRGEYPTY
                     ALKELERKGINIVMEEDDKKILKENTVDFISFSYYSSRLTSADPKVNILTEGNVFASL
                     KNPYLDASEWGWQIDPLGLRITMNSLYDRYQKPLFIVENGLGAVDNPDENGNINDDYR
                     IDYLRAHIKAMIDAVELDGVDLWGYTPWGCIDLVSASTGEMKKRYGFIYVDKDNDGNG
                     TLKRSKKKSFAWYKKVIESNGEEL"
     gene            complement(77711..79627)
                     /locus_tag="KRM55_000062"
     CDS             complement(77711..79627)
                     /locus_tag="KRM55_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1592341.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGIYGVTEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQELITVLA"
     gene            complement(79701..80561)
                     /locus_tag="KRM55_000063"
     CDS             complement(79701..80561)
                     /locus_tag="KRM55_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1592342.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(80912..82099)
                     /locus_tag="KRM55_000064"
     CDS             complement(80912..82099)
                     /locus_tag="KRM55_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1592343.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(82113..83504)
                     /locus_tag="KRM55_000065"
     CDS             complement(82113..83504)
                     /locus_tag="KRM55_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBH1592344.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(84099..85799)
                     /locus_tag="KRM55_000066"
     CDS             complement(84099..85799)
                     /locus_tag="KRM55_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1592345.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(85771..87174)
                     /locus_tag="KRM55_000067"
     CDS             complement(85771..87174)
                     /locus_tag="KRM55_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1592346.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELDEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGMYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(87439..87930)
                     /locus_tag="KRM55_000068"
     CDS             complement(87439..87930)
                     /locus_tag="KRM55_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1592347.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEADLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(87956..88768)
                     /locus_tag="KRM55_000069"
     CDS             complement(87956..88768)
                     /locus_tag="KRM55_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1592348.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(88781..89740)
                     /locus_tag="KRM55_000070"
                     /pseudo
     CDS             complement(88781..89740)
                     /locus_tag="KRM55_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(89858..>90415)
                     /locus_tag="KRM55_000071"
     CDS             complement(89858..>90415)
                     /locus_tag="KRM55_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1592349.1"
                     /translation="IKEFCISSCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRN
                     KARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDV
                     SWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNE
                     THDRDINASINILKEGLRLITIQNK"
BASE COUNT        29182 a        16305 c         9617 g        35311 t
ORIGIN      
        1 tataattaat atacttttta atcaaattta aacagaataa ttataccaat atataaaaaa
       61 atttctaaaa aacaataaaa ttaagttata aacaccaata tatttctatt atttcaataa
      121 gtatacaatt agattagaat ctaacgctag taataaaaaa ttactttccc agaatagata
      181 taagcttcat tttatcgttc aaataatgaa aatatatttg atttcatgca aaaagagtgc
      241 ctaatgaact aaaaagttca ttttgagaca ctcatttttt tatataaatt tatatagttt
      301 ttaatcgttc gcattcaacc actcagttaa gacttttata tatttctcat tttcttcaac
      361 gaatggcata tgtcttgaat actcaaataa ttcccactta ctattaggta ttctatcata
      421 catagtcttt gcaatatatg gtgaacataa atctattgct ccactagtta ctagacaagg
      481 ctcttttatt tcatgtaatc tatctgtaaa ttcatatcca gaaagagttc ctgtaggaga
      541 aaattcattt tgtccccatc ctacaatata tgcttcagaa cctgattttt taggtcttct
      601 caggcactct ggagaatctt ctgtcacttc acctgcacaa tacatttcca taaatctttc
      661 taatgcatca ttatattctt tgctagagta atctccagta tttactgcat caagtaatgc
      721 tttttggtca acctcactca tatatgatat tcttcttttt tgttctttct cccaaagttt
      781 tgcagaagaa agagtagatg aaaggatgta agacttaata ccttttggtt tatattcaat
      841 agcataccaa atagcctgca tacctcccca agattgacct aacagatgaa tttcatcaag
      901 tcctagatgt tttcttagtt caataagctc ctctatccaa gtatctgcat taaatagctc
      961 aggatgccct tctacaaatg aatttccaca accaatttgg tcatacatta ttacttgtct
     1021 accactttca gctatcttat ccaatacctc aaaatagttg tgtgtagaac ctggacctcc
     1081 atgaagtaat actaatggct tcttcccttc cgtattttct cctactatac ggtaatacgt
     1141 tttaaaacct ttaaaaggca tatatccttc agtaattttc atgtttatct cctccaattt
     1201 gtaattataa acaataatca agttcattaa caatactatt taaaacctct tatacatatt
     1261 tgattatgta ttttaatctt tatacctact tttataaata gtataacata aaagttaaaa
     1321 atctctatac taaaccaatt ataaaattat attaactata taattttatt ttttaataat
     1381 agtatataca tatttgatta ttttcatttg ctgcttaaaa tcaattttaa gttttcttcc
     1441 tataataaac ttcctctttg tggtctcatg ttagtctcta aatttaaaat tttacaaaaa
     1501 attttcataa aataaaatta tattgattgt atctaaacaa atagggcaat aaaataatta
     1561 agtatagtta cttacctttc aagcaatatt agttttatgt tagaatttta ttatattgat
     1621 ttacaggagg tttgcatttg aataatatta attcacttaa agtaataaaa ttatctcttg
     1681 gatgttctct tgctatattt attgcttggc tattaaaatt agaatactca atggttgctg
     1741 gagttatagt actacttaca gtaaaggaca ctaaaagaga aactcttaaa ggctccattg
     1801 gaaagattta tggttttctt ttatgtacta ttttttcata tttatgtttt aatattttag
     1861 gatataattt gacttcattt tcaatattta tatttataat tataccactt tgttttttgt
     1921 taaatattca agatgttatt gctatgtgtg tagtcatagc atcccattac taccttcaag
     1981 gagaaacttc tatcaaatgg attttaaatg aagctggaat atttgcagta ggaactggaa
     2041 taggtgtctt aataaatatg tatattccaa caaatataca taaaatccat gaagttcaaa
     2101 aaaagttgca ggaagaagtg agtattgtac ttatagacat tgcagatatt attgtaaatc
     2161 ctaaaaaaga aaatggatat agtagagatt tatatacatt aaattcactt attgacagca
     2221 gtatttctga aacttacgat aatattaata atactttatt aagtgatact agattcttct
     2281 tagaacatat ggatattata aaaagccaac gggatatctt agaaaatttg tatagttatg
     2341 tatctcaact aaattctaca ccaccacaag ctcatattct atctgctttt atacataaga
     2401 taggttatac tgaatttgaa gctgaaacag gcaatcttct tcttgaagaa ttaaagagac
     2461 taatgattag tatgaaaaac cagcctctgc ctgttgacag aacagagttt gaaaatagag
     2521 ctattttatt cctatgcttg actgagttaa aacagttttt agttaatcgt aaacatgctc
     2581 agatgcttag agataataat ttttataaat aaaaaggaga gaaatctagc agttgacctg
     2641 actacaaaat atcagatata atattaaatg cgcccctagt aagagggcgc aatgtttata
     2701 acttattcta ctgtcatgat taaatcatta ttcatatcga acatacatta tttgaccaag
     2761 tccaatatta gctttttcat cagtgatttc tattttaata gtcacatcat tttttttaca
     2821 gtacttcgct aattctgcac cagaacgatt tttaccacta aaatctaaag aaaatggctt
     2881 atcatattta aaaggatatt caacaggttt accctctggt gctaatgcaa acatcccata
     2941 tggtgtgttc ataaatccta ttacagcaat cgtaagattt gatgggtcta aatttgattc
     3001 actacctgta aatgtaattg tatttactga tgaattaact acactacatc taacaccttc
     3061 atacattaca tgtttttcat ttatatcttc tccttttttt ccaaaatttg caacagcctt
     3121 tgccccttct tgatgtggta acatagtgtg cttcccaggt ggtgctggtt tctgtgtctg
     3181 ttctggtttt accgtctgta ctattgcacc aacttttgga tatgctgtct tatcaaatgg
     3241 taatgggtgg ctaagactct tgtatatgat atcctttcct gctgatttat tagcatcaat
     3301 atctacatga tacaaacgcc catcaccaaa acggataaga ttccactggt ggtcatttga
     3361 tgtgctgtgt acataataag attcaattcc catagcatca cacaaagctt tcatgctcct
     3421 agccattcct gagcatgcac cttttttagt aaccaatgta taggcagtat ttgctccctc
     3481 tactgcattc cagtcaacat atgttgtgtt atttttaatg tgattgtagg caactaaaat
     3541 cttagcatct gtggtcatat tctttgtgat tttcttgttc ataaaatctg ctgttgcttg
     3601 tgctactgag tttagttggg cttgtgacag ctttggacca tatacgctat tggttccagt
     3661 gacatagctt tttggtgttt ttgctgttac ctctttggct gtcataccat aaactgtcat
     3721 actcatacct gagattaaaa ctattgttgt aatcaataac ttggtagcta acttcctaat
     3781 tttcttcata cttaatattc tcctttataa aacattgtta cttcctattc tctaccatta
     3841 ataaaattaa tttaggattt aaaaaggtgg attgtcaaca tgtatatttc tccattcata
     3901 cattcgtgaa atatttaaat tttatggaaa atctaataga tattttctag ataatttgta
     3961 tacaatacaa ctcgcaaatc agggtatttg ctgttagttt gagaaaatga tgatgattaa
     4021 tacattcgga atctttgacc tataataaat accattgtct tcaatcatta ataatggtaa
     4081 gagtaaagag aattatcaat aatacagtta aaatcaactt tgtatacatt tcatacattc
     4141 tctcccaaca acattatact tcttataatt tgtatattca atacgttttc tgggaaaata
     4201 taggatatat ctataaaaat ataaaaaagg agttgaactt aaaatttgat taaaaaaaat
     4261 caattttaag acaactcatt tgtattataa aaatgctata tattattatt aagtaagtca
     4321 atattttaga tatttatcta tttcttattg acttacgctt atagcctaac ttatttgttt
     4381 agttgatata taacctagtt ttaagcatta ttaatattta aataatcaag tatccttttt
     4441 gtttcttgta gtttctgttc tgcctcattt aagttttctt gaattataga aatatatatt
     4501 atatctatca acgtaagcat tgctattctt gaagaaatag ctccttctct aagtcttttt
     4561 tctatatttg gtactactag ctttaaatca ctaatcttac taagatgatt gtcactatat
     4621 ttagttatac aaatgacctt acatcctttt aattttgcat tttctataga ctttattact
     4681 tcttttgatt ctccagagta agatattgct atagctatat cttctttatc tacatttgaa
     4741 gataccataa gttgtgtatg actatctaaa gaggtaaatg cctgtttatt tatccttaaa
     4801 agtttcatct gtaaatctag tgcaactaaa gccgaaccac ctactccaaa tatatataca
     4861 tttttagcct ttattatctg ttcaactgct tcttttatta tatctttttc attcaacaac
     4921 cttgtttggt tgatagtctc tatgtttttg tttgtaattt tgtttataac actatctata
     4981 ttacaatcat agttttcatc tacatatgtg tattcatttt ctttgcccat caaatcttta
     5041 gctatctcaa tttttaaatc cccaaaaccc gaatatccca tttttctaga aaacctaact
     5101 atacttgctg tacttgtttt tgagtttgac gccaattctg atacagaaag cttacttata
     5161 gcctctgtat tattaagtat gtaatcagct atttttttat ctacttccgt taaatcttca
     5221 tatatctgtt ttaattttaa aatgcaactc atactctatc acctctacct atttactata
     5281 atatttcttc ttagcaagta aacatgctcc taaatctgga gtcaacactg gtctcactat
     5341 accaaatctc gttttattca aatatttttt aagtggctct aatattaaat ctcctgactt
     5401 aaacactcca cctgaataag atacctttat ctttgtacct tgttcaaaat gatgctctaa
     5461 tcctattata agcctactta attcataagc tgcatcatca aatattttac tagcagtatt
     5521 atcaccttca ataactgctt ttaaacatat cgtagcaaac tttgctattt ctattctatc
     5581 tccttgtatt tcatcattta catattttat tatgtcataa tcattctcta tattaagatg
     5641 tctttttatt aaatcatata attttgtttt tgaacacctt ccatcagact gcattgtgaa
     5701 catttttaag gtagccattc ctatataata cgctgaacct tcatctccta atacatagcc
     5761 ccatcctcca catctgtgaa gattcccatc tttatctaaa gcctgtgcta ttgaaccagt
     5821 acctgcaatt atatttatac ctttttcccc atttaaagaa cctgctaatg ctatttctac
     5881 atcattacct agagtataat ttatatgact atatgcattt tttgttgcta cttctaatgc
     5941 atacaatact tcttttattt ttccatatcc agcaagtcca acaaatgcat acgttatttc
     6001 ttctacattt atcttagcat ctttacaaac ttcttccaac ccagttatta ataatttcgt
     6061 tagattatca aatcctattt gattataatg acaagttcct ttggttatgg ttcctactat
     6121 atttaattct tcatctacta atgtaaatgt tgttttcgtt cctccaccat ctacacctaa
     6181 aaaatacata ctatcctcct acaatatctt taataattct ttcaatactt aatatctaaa
     6241 aataaccttc caatgctgtt tttttaatat tgaaaggtta tcagtactat tatttatttt
     6301 acaatttttc tattgatttt aaagcttcac ttatataacc ttcttgtcta tctaggatac
     6361 tctttgcact atccttatct aaaccacttt ttatcataaa tatagccaat ttaacgctat
     6421 tatctgcttc ttctaagaat ttttctgcaa catcatattt tacatttgta gctatcatta
     6481 ttattctttt tgctctttca accaactttt catttgatgt cttaacatct accatcaagt
     6541 ttgagtatac ttttcccatc ttaaccatag aagctgttgt taacatatta cataccattt
     6601 tttgagctgt accacttttc attctagttg aacccattat tacttctgcc cctactataa
     6661 tgtttattgg taaatccgct tttttactca tttcactatt cggattcata gttattgata
     6721 gtactgcaca ccccaattcc ttagcatact ccattgcacc tataacataa ggagtccttc
     6781 ctgatgcagc tataccacat ataacatcct tagatgtaac tcctctatct attatatctt
     6841 gctttccaag ttctttatca tcttcagcac cttctattgc tttaaatatt gcttgatttc
     6901 caccagctat tatagcttga acaagctcaa aatccactcc gtaagttgga ggacattctg
     6961 tggcatctag tattcctatc ctcccactgg tacctgctcc tatatagaat aatctacctc
     7021 cctgtttcat tctatctact attatattaa cagcttttgc tatactctcc ttttgttctt
     7081 caacagcata ggctacagtt ttatcttcgt tatttattaa ttctattatg cctaatgtat
     7141 cttctttatc tatttgcaat gtattcttat ttctaccttc tgtaactaaa ttttctaaag
     7201 tttttattaa catatcattt cctcattttc ttaatattaa atttttaaac acattttaat
     7261 tccaactttc ataattatat ttttataata aattaatatt ttcataataa attattttgt
     7321 tgagggttta aaattaaact tttgccatgg tttaatataa tctaatataa ataattcttc
     7381 ttttcttata tatcctacta cattcgattt accactgttt ttcatatcag tcaaagctat
     7441 ttgtaactcc cctgcataat gaccatattc actactttca attactatat ctcctctttt
     7501 tattatttta ggagtattaa atagttcaaa tttgtatcct ttatatttaa cacgagattg
     7561 agtagacctt atcagactgt cagatatgtc ccctctatta aaatgtattt cttcaaagag
     7621 tatcttcttc tcaacttctc gtatattttc ctctattgct acatcaaatg taaccatatc
     7681 ttttctcata gaacctaata cctttagctc ctcatatgtt ggataacaat ttgatattat
     7741 tatatcattt atattattca tagctattat atgctttact tgaatatcta taggtagatt
     7801 tctgtgcatc tcaattgttg gaagcccatc agttacaggc catggtccaa atgtagtttc
     7861 attttgactt gttacaaaaa ctgctgttct taatccatac ttattaaatc tttctgtaca
     7921 ttttataaag tgttttaaat ttaatccact atatctatgt ggataaaagt tatgacatcc
     7981 tatcaaattt tctttatttg gttggtagtc cattattgta tctatataat tagtattatt
     8041 actcatattg atttctattt taagattttg aggattaaaa gtcattaatg cctcttcaga
     8101 acctgtaaat cccatatcaa gccttattcc gtctgccttc gtctttttaa aaaaattcaa
     8161 atctttgtag cttatttcta attcaccaaa tactctggga tttacatcaa gtattacctc
     8221 aaaaccttta aacttagcgt attcatttat acttttaaat tttttaatta tattttcttt
     8281 agtatcttta actgataata aacatgaaaa tatacgtgta aatccatttt cagcagcttt
     8341 atctatataa tcatatattt ccttagatgt tgttttttct ggataaattg atattcctaa
     8401 tcttcccatc tgtgtcatct ccttatatcc tatatgtgtt taaatttatt tcgaattaca
     8461 cgaaactttt ttaaaaattt gatgaaaaaa agtttcatat atatttataa aaaaagaaaa
     8521 gtttaccttt tcttttttta taaacaatca acaaaatatc ttcgttactt atttcataac
     8581 tgttatactt tgaaatttat actaatctaa tatagttttt aattaataag cttcttgctc
     8641 ttcaactttt tcttcatgaa gcaacctctt atcgtacatc ttgacaaatg gatagtaaat
     8701 tattattgat atagctatac ataataagtt aagaactgaa gctctccaat ctccaccagt
     8761 ggctaaatat gcccctactg gtcctggtaa tgtccaagga gcagtaacta ctactctgga
     8821 tactaaatta gcactcatag caaaccatga aactgttgcc attactattg gtgctacaac
     8881 aaatggtatt attaatattg ggtttaatac tattggcgct ccaaatatta ttggttcatt
     8941 tatattgaat attgctggta ttacagttgc ttttcctaaa gactttccat aagctgattt
     9001 tgctctaaat gcaagaagta aagctaagcc tattgtagct ccagaacctc caatccatat
     9061 aaaccattga aaaaagggtt cagcagcaat acctggaact gcttgacccg cagcatatga
     9121 agctgtatta gcatctaata attgtatcca taaaggtctt gccaatgaac ctattattga
     9181 tacaccatgt attccaaatg accaaaaaaa cgttattaaa aatattagta taattactga
     9241 tggtaatgtg tcagtggctg aaactaatgg agttactaat ttagctatga agccatgcca
     9301 atcaaaccct aggaaataag taacaatagc cattaaaatt attattaatg cggctggtgt
     9361 cagagcttca aaagaccttg tgactgatgc tggaactgct tctggcatgg ttatcttgaa
     9421 tttagatttg tcagtaaatc tataaatctc aacacctatt atagatgtta caatagcaac
     9481 aaacattgaa cctccaccaa gattagccat tggcatttgc catccttgag gaattgaatt
     9541 ataccaagct aaaagttctg gactcttttc aactatcttt aataaatcag gggtaagacc
     9601 ctctattgca gtaggaacta ttgtcaaaag gaatgtagct gtagctaata aacctcctgt
     9661 caatccatct aacttatatg actttgccaa actataacct atgccaaatg tagaatatac
     9721 tgatataata aaaaatgtca ttctatatgg tagtaatatt gtaactgcat tttcctttag
     9781 atactgagtt accccccatg aatctggtaa tggaggaaat gctaatatca agaaaaatga
     9841 cccaactatt ataagtggta atgaagctac gattccatct cttacagctc ttaagtgacg
     9901 ttgttctgcc aatctggcca tagaagttga taatttagtg tctaaaaatt ctgtaaattt
     9961 atctagcatc ttttctctcc ttaattaata tttattttta ttatcattaa aatttttata
    10021 aaatcaactt tcttctaacc taacaacact gcaactacta tttactcaac agctcttgaa
    10081 cttgttttaa taactttggt cctcctaatg gactataagc ttgtgcttgt attaatgcac
    10141 atggtacact aacctcatca gcaaaagctt ttaaatagtc aaatctatgt ctaacttgtg
    10201 gagctaccat agcaatatcc catccatttt taacttcatc ctcaaactct tgagtaccaa
    10261 cagccaaaac atctatatct attccatttt ttgctccttc tttttgtaat gcattaactg
    10321 ctatagcact tgacatccct gatgaacaaa caaataatac tctcatattg attccccctg
    10381 tttttttatt tcttttcaat cattatagca tgtatttttg attacaggaa tacgtttgta
    10441 tatatttttt catattttac attttaaatt gtaattttat ttcatgcatt tatatcttgc
    10501 tttaattgct ttatttatct aatcattctt ttgtctaaaa ttacacacta cttaaaatac
    10561 tcatatcttt tcttaaaaaa gtattgagac tatcttatta ttaacataaa atagtctcaa
    10621 tactttttta aatatgtatt cctttatata tccagaagta acctattatt gcaaatgata
    10681 aagcaaataa aatatacagt ctaaaaaatc ccaaagaaaa acctctctta gtttcaacaa
    10741 agtatcttgt atatgcaact gcaaaagatg taattaatga atttcttata acaactccaa
    10801 atctattatc tattccaaat atagataata acaaaggaaa aactacagta cttacaagag
    10861 atgaaactat tagtattaat ccacttttaa aacttatagt tggaatatta taatctgttc
    10921 tttgattttt ctccatttgt ttcttagtat ttttattact ttttgtactt tttgcatttt
    10981 tataattatt atttttcttt cttttctttt ttttattatt agacatgtca tttacctcca
    11041 aaaggtttag gtgttatatt ccctaaaata actttatttt tagcccctgt tgcagatatt
    11101 acattagaaa aagaattatt taatgtttca ttgcccaaga ttacaaatgc caaagcctcc
    11161 tttgcatcag aagaataccc atattcatct tgagttaata cttcaacctc taataataac
    11221 tcttttatat atcctattaa agttaaatta tgagctcctc cacctccaat taataaagta
    11281 tctacattaa cctttggaag tatgaagttt ttataattat aatatatagc ttttgccgta
    11341 aacatagtta ctgttgctat caaatcatat ttatctacat gtttatattt gttaagcatg
    11401 ttatccaaat aaacttgtcc aaatacctct cttccagtgc ttttaggtgg cgcttgacta
    11461 agatacttat gactcatcaa atcttttaac atttcttcat taattttacc ttttgatgca
    11521 aagtatccat ttttatcata ctttctatta aataatcttt gacatactcc atctattatc
    11581 atatttcctg gtcctgtatc aaatgcaaat acatcatcta tgttacatga tttaggtatt
    11641 atagtaatat ttcctattcc accaatattt tgaagtgcta aatttttatt gttatcacta
    11701 tataataaaa attcactata tggtactaat ggagcacctt ctccacctgc tgctatatcc
    11761 attactctaa aattagatat tacctttgta tttgtttcat atgctataac tgctggttca
    11821 cctatttgaa gcgttgaaga tacaaaatta ttataacttc ttggtatatg aaagattgtt
    11881 tgaccatgag atgcgataaa atccaaattt gctatatgaa agtttgcttt atgacacact
    11941 gattttacag ctttactaaa taaatatcca agcttaaaat ttaagctaca gattaaatca
    12001 acactcgatt cctcttctat acagcatttt cttatttcgt cttttatatc tttaggaatt
    12061 tctagagtta taaattctat ttgcttaact ttagtatttc taccattctc actaatttca
    12121 gctagtactg catcaactcc atctaaggaa gttcctgaca ttaaacctac actatacata
    12181 gttatcatcc ttttaagttt atagttattc ctccccaaat caaggtatta agtttaataa
    12241 ttttagaatt aatcttattt catctttaat tacgataatt tactcttacg aaattaatcg
    12301 agttaatctt atacacgttt tttaccttag ctaaatctta cattaattta ttttcagtgt
    12361 caatgtaata ccatgtaatt ttttttcaca aacaaaacat attctctctc caaaaaccat
    12421 attaaaatag ttactacaaa taaaaaacat accaggtacc tatctgatat gtttttcata
    12481 tataataatt attattttat aatatagata gagcatcatt taagacacta attaaatctt
    12541 cactattttc aagaactaaa tttattctta ttgtatatgt cgatttgtat atgatgatag
    12601 attttatagt ctaataacct aactatctag gcttaaataa tctgatatat cataaaaata
    12661 gatattaaaa attgtatatg aaccattttc cgaacatacc tcaatctcat gccctaaact
    12721 atctatcatt ttctttacaa aatacatccc cattccagta gacttataca attgatttct
    12781 tccatttttc cccgtaaatc ccttgtcaaa aaccctagat atatcttcct catttatacc
    12841 tataccaaaa tcttttatag ataataccac tccattttct aacttttttg aattaaattc
    12901 aatcttacca acttcctttg aatactttat agcattatta ataatttggt ctaaaacata
    12961 tgacatgcat ttagaatctg tgtaaacatc attttctaat tcattcaaac taacttctac
    13021 attatttttt ataagcaaaa atgaattatt ttttatagac atttttacca atttttctaa
    13081 attaaattta tttataaata catcttcaaa catagtgttg cttctactac tatacaaaat
    13141 agagtttact aaaaaattta tctttgcaac ctgattctta atatccaaac tatcttctat
    13201 gctacttaac ctatctgtaa ttatacttaa agaagatatt ggaattttta tttcatgaac
    13261 ccatttagct atgtactcat ccaattcttt taatgattgt ttataagtct ctatgtcact
    13321 attatttttt atttttaagt tttctataat atcttttatt agattttctt caaaagattg
    13381 tccatcaact aaataactgt ctatttcacc actattttct atacaattat ataaatttgt
    13441 gtaactattt ctaaaattta tataatctat aacaaaaaat accattatta taaacagcac
    13501 taaaaaatct aaatatatta actctgaata tttattttta aaaatatcta tagcaaataa
    13561 gtagatattt attatactaa ctacaactaa aggtagagca atatacttag acctaccttt
    13621 taaatatttt actagcattg tattatatat cctatcccct tcttagtttt tataaaatca
    13681 tcaaaaccta gttctttaac tttacttctc aatctattca tatttacagt aagtgcattg
    13741 tctgtcacaa actcatcatt atcccataga gtcatcataa gactttccct tgatacaacc
    13801 ctattcttat tttttaataa taatgttaaa atttttattt cgtttttagt caactctata
    13861 cttttatcct tatacttatg ttttataatc cctttcccca catcaaacat caaatcttca
    13921 caatacaaaa tactattaga atcactataa ttatagactc ttcttattat accatttatt
    13981 ttggtaacca atatttctat agaaaatggt ttggtaatgt aatcatctgc tccattattt
    14041 atacccatta ttaaatccat atcagaatct cttgatgata aaaatattaa tggtacattt
    14101 gaaatagctc ttattttttc gcaccagtaa aatccattat ataatggtaa atttacatct
    14161 aaaagtacta catctggttt tttatctata aattcatcta atactacctc aaaatcatca
    14221 attaattcta ctttaaatcc ccatttttca agtgctaatg caatctcttt tgataaatca
    14281 atatcgtcct ctactaataa aattctatac atttgtatat tctccattat cctaatattt
    14341 cactatgcta tgaattatta atatcataac atattttata tgaatttatt acccaaatta
    14401 tttagttaat caacaaggag actcttatta caagaatctc ctttctcttt attaatatat
    14461 caactaattt ttatacacta cactcttaaa cttattaaca gatactgctc catatattat
    14521 gaatattatc aaacatatca ctaaacttag tatatatata ccaaataaat cggtcatcaa
    14581 taaatctcct gctaatctca atgcaaaata actagatata gttgcactta acattggcaa
    14641 agtataaaaa atagctactt ctttaagtat agctctattt atatcttttt ctgtagtacc
    14701 tatttttaac aaaatcttat atttctcttt atcttcatat gcatcactat atattttcat
    14761 atatattata cttccagcta caattgcaaa gactaagaat aaaaacacaa gcactacata
    14821 tgcaaacttc atccattgac tctcaccttg agctttatat ccattttgaa tatacacatt
    14881 ttttaaactt aaattctttt caatattgtt gaacattact tgactatttt cttcttgaaa
    14941 tacctttgca ccataaaaat acacttgttg acccttatct cttagtttaa aatatgtatc
    15001 atcatttacc actataatac tttgattaag tcctgtccct agtactggaa cttttacttc
    15061 tccccttgaa atattatata actgaccatc aagttttatc ttggcttctt ttgtagctat
    15121 tgatgctatc gtttgagggc tttttaactc tattacatta tttccactaa ctaatctttc
    15181 accatactct tttaattctt tatcattgcc attcacttta agagtattac aaaaatcact
    15241 atatttcatt atagtatctg ttgtatcata agcttctttt atatctgttt tctttaaaat
    15301 tgttagttct ggatttactg agtactttat cttattagta tcttttatta tattctctat
    15361 ttgtttttta ttcacttcat ctttatccat tgaaactatg ctaatagtgt acacatttct
    15421 ttgttcttgg gcattcttat gtatacgctt catcgcaact gaagcaccaa gagttgatat
    15481 tgttgtagtt ataattatag ctattatagc ataagtttta tagtttttat ttaatcggta
    15541 gtttatattg tttattgcaa ttatattatt tccattaaat aatatttttt tatttttgat
    15601 tataatatca aatataacag gcataactga tttgaataat ccataagtac ctactattat
    15661 tatacctata acaggtagta cactagttat atctccagtt cttatattgg tagaaagata
    15721 gtagccatat cctattacta taattgatac tatagctaat atatatatac ctattcctac
    15781 ctttggtatt ttttcttgtt ttttagatat attgattaga tttattacac tacttctaca
    15841 tattgttata aaacctttta cagccattat tataaatata gaaataaaga ttaaagtagc
    15901 atatagtata gcttctatac taagtccatt agataccttt atattaaatc cagataactt
    15961 tattatcact acttgaaaaa atctagatgt tattatccct ataattattc ctgttataca
    16021 agaacttatt cctataagca tattttctac aaaatatatt tttcctatag tatataaatc
    16081 taatcccata aaagacaata ttccaatttc tttagaccta ttcttaaaaa atatatttgt
    16141 tgcataccat ataaagaaaa ataaaaatac tgatagtatc attattacag ctactaacac
    16201 tgatagtgta aattttttat tttcatcttg taacacattt atagcatcac catatcttaa
    16261 taattcaaaa ttagttagca caactactga aaaaaccata gatataaaaa atgctagata
    16321 agttcttatg ttactcttaa aattattata cgcaattcca agtatactca cttacatctc
    16381 acctcccata gaggctagca tatccataat ttttccataa aattcttttc tactatttcc
    16441 tttgtttaat ttacacttta tatttccatc atttatcata tatacttcat ttgaataact
    16501 tgctgttaga gggtcatgtg taatcattat aatagtagcg ttattttctc tgtttatttt
    16561 ttctaatgat tctaaaagtt catatgctga tttagagtct aaagcaccag ttggctcatc
    16621 agcaaatatg actgttggat ttgtaattaa tgacctagct gctgcgcctc tttgtttttg
    16681 tcctcctgat aactgatatg gatatttatc taaatgattt tctaatccaa attttttagc
    16741 tatagaaaat accttagctt ctatctcctt acttttcttt tttcctaatg ctagaggaag
    16801 tgctatattg tccattagtt tcatattgtc taatagatta tagtcttgaa atataaaccc
    16861 tattttttct cttcttaatt ttgatagttc attatttttt acttttgata tattaattcc
    16921 atctagtatt atttctcctg aagtttgttt gtcaagtgta gacattaaat ttagcaatgt
    16981 tgtctttcct gcaccagatg gacccattat tgatataaaa tcaccttcat tgactgtaag
    17041 agatatattt tttaatacat ttgttttaaa tccttttatt ccataatctt ttgatatatt
    17101 ttttattttt aatatttctt tcataataat agcctccagt tgctaatttt ttaatatata
    17161 tttattttaa aggttttata taaataaatc cttaagtaaa tattacattt taactgttag
    17221 cattacactt ttgtaacata tggaagacta ttataattat aatggaaata tcttaaaata
    17281 aaagcatgat ttacttcttt gtataaacaa agaaaagaag ctcctaagaa gcctctaatc
    17341 tatacaatta ttcttctcta taaaaaacca aaatacacat tgattgtggc aaatacagat
    17401 actataaaca agtgatatta ctactatata ttaaaacaat tattcctgaa gataattcaa
    17461 taagactatc aagcaataag ctaagcatcc aaaaagactt aataccatta atgtataatt
    17521 atacccaata ttaatgctca aaaaaccagc aacagttgga ataatcagag atgaacctcc
    17581 cataaatata cttaaagcta ttaattggct actacttcta agttttttag gagaaacttc
    17641 aaatattaat ctttttgaag taattaaaat taaaggagta gaaaacactt gaaaaacaca
    17701 cagtataata atgatatttg aatcatttgt taaagcaaat aatagaaact gaactgttat
    17761 cataatagca cttaatttta ataagtttaa actgctatat ttttttaata aataagaacc
    17821 agccagatat gttggtatct ctaacaatga ctgtaaagac cactttaaag atatctgaga
    17881 atttgtagca tttaaagcta tcattttatc tattacagta cagttatttg ctaccaccat
    17941 tgagtataat aagaataaaa tacatactag taagatatat tttttatctt ttaataattc
    18001 aataatatct ttattagtta catttatttt cttattaatc ttttcaatat caggtaataa
    18061 tagtatattt ataataagta atactacaat taaaccaatc gctacagata atccaaaata
    18121 tgagaatcta agaatcaagt aagatgctac catacttcca atagcccatc caatcgaccc
    18181 aaaagtctta ataaatgaca aataattatt aatattatct ccacaaccta ttatccatgt
    18241 atcatataaa ctacagcaag tatttaataa tcctcctgat aaagcaacaa gtaataagta
    18301 tattataaaa gttgcagatt cagtagaaaa cataataact gatgcaattc cataaactga
    18361 taaactaatt aaaacaattt ttttcattgt ttgatactta tcagctaata ctccaaataa
    18421 taattgaaac aatatattgg ttattgcata gctcgataat ataattcctc tttcaaacgc
    18481 tgagtaacct aattttgata agaaaggtgt gaattttgtt gaagcaaagg caaaaataat
    18541 atatgagaaa aaatagaata tgataaattt aaatttaatc gctttattaa tcataatcaa
    18601 tcaaaattga taactttaat accactattt ccttcctgat ttaagtttga aagatgatat
    18661 tttaccgtat taggattctc tacaataact aaaggaatat ataaagtatt ttcaagtaac
    18721 ttattatcaa tttctactaa cttttccccc atattaactt cttgaccttg tttaacttct
    18781 aatttaaagt tttctttttt tgttgttgca ctatccaatc caatatgaat aagaatttga
    18841 acatcatttt gcaatttaat tcctatagca tggttagttt gagcaataaa acttattact
    18901 cctttagtcg gtgatttaag aatattgtcc tttgctatca tagcaaatcc atctcccatt
    18961 accttagttg aaaatacttt atcaggaatt tctccaagat taattatttt tccatcaatg
    19021 tatgaattaa ttgtaattgc ttcttttttt cttttaaaga acattataga cactcctcta
    19081 tataattaac tttattctaa ttatcattac aaataacgat attaagcata ctgcaattga
    19141 ggaaaaaaga gccttatagc tctttcccca ttgtagttct ttaatactgc ttatgatttg
    19201 tttaattcca acaaatttat aaatataggt aaacatgata acaatagtta ttgtgtaaat
    19261 ttggaatatc tgccctaata agactaaata gaaagcaatc atgttttctt ttatctcttt
    19321 attctttttt atattgtaaa taacatatgc actgtatact gcactaaagt tagagattaa
    19381 atttaaactt gcattaacat cattgtttaa aagttgtgaa aatgaaatat ttgtaaataa
    19441 tgatgtcaat tctaaataca ctatatataa aacaggtaat attagaaaac aaaccataac
    19501 cactgaaaga aatatatttt catcttttaa tactgctgtg atatttttta ttttatttgt
    19561 tatcatgttt ttgttctcct tatttaaaag ttggccagaa atccttatta gccacaatca
    19621 tttcatctaa gatttctttt gctacttttg cacttggaac agttttactc atagtaaacg
    19681 actgccataa tttttgataa cttttttcta tccatgcttc tacagctaat ttttcagaag
    19741 caacttgttg ttccattaaa cctttttgga aagttggaat tttacctata gacataggtt
    19801 caaccatatt ttttccaaca aggcaaggaa tttcaaccat tgcatcatct gcaaaatttt
    19861 caatagctcc attattagga acaatcagta aaaatctttc ctgagtatta aatgctaatg
    19921 cacaagctaa ttcaacaata aattgagaat gttcacttgc atcaaaccat gtatctcttg
    19981 ctgtgccatt ttttataatt ctttcacatt cttcgaatgt atccttttct cttctatcca
    20041 taatttcatt tgctcttgta taatttggat tagcatgttc aacagtttca tcagccatta
    20101 aataatattt taaataagta ttaggtaatg tagttggttc tatttccaat aaatcctttg
    20161 ctgctctcat agtttctaac caactagatt ctttgtgttg accttgaggt gtaaattcct
    20221 catatccttt tttagcacaa tattcctgta atttaggcat taaatcattt ccttctttgt
    20281 ccttaatact tgtccaccac ccgaaatgat tcaatccata atatctaaca tcaaagtctt
    20341 tacgagaatt taaacctaaa actctagcaa atatttcctc taaacatact ggcatatcac
    20401 aaatattaat aattcttgaa tttggtctta atacacgaca tgcttctgca actatagctg
    20461 ctggatttga ataattaagc atccaagcat ttggagaata tttttccata taatcaatca
    20521 tttcgattat tggacctatt gttcttaatc cataggcaat tccacctgcc ccacaagttt
    20581 cttgaccaac aaccccatat tttagtggaa ttttttcatc ttgttcacgt aaagcatata
    20641 aaccaacacg aatttgtgcc attacaaaat caatatcagt aaatgcttct tctggatttg
    20701 ttgtataact aaatttaatt tctggatttt tctctctaac aattattgca catgcttcag
    20761 caacttttct ttgtctatca tcattattat catataattt aattgattca ataggaaatt
    20821 tagcaacact ttcaattaac attgttacaa ttccagcagt ataagtacta cccccaccag
    20881 caattagtat cctctgtctt tttctttcca tctttccttc tcctttataa taaattttca
    20941 aattcttctc ttacacttgg tactgaaagc ccaataataa tctgaatagc ttttccatta
    21001 tgcactaaac catgtgcacc tactgcctta aaatcttctt ctttagaaat aattgagtca
    21061 tctttcaagg ttaatctcaa cctcgtagca cagtttgtaa catctacaac attttctgct
    21121 ccaccaacta attttatgta ttcagatgct tgttgagagg ctttactcaa tttatttcct
    21181 ttttcatctt tagtttctaa gtattcattt ttagtatata gttttgtttc ttcactatct
    21241 tcctctctac caggagtttt catatcaaac ttcttaatta agaaagtaaa tacaaagaac
    21301 cagataaatg aaaatataat ccctacaaca acttgaacaa catatacctt ccagtgatac
    21361 attccaagag gaagccaatt taatacaacc cagttaataa ttcctccacc aaaatcacca
    21421 acaactccta gggcaaacga aatcgtttgc aagcatgcat ctaaaaatgc atgtactagg
    21481 aataaaagtg gtgctacaaa taaaaatgta aattctaacg gctcagtaat tccagttaat
    21541 actgcagtaa gagtagcagg aatcattaaa cctaatactt ttttcttttt ttctggcttt
    21601 gcagttacat agaaagcacc aaatacacct aatgaaccaa acaccttcga taatccggat
    21661 aatgaaaatc cgattggata catttccttt agagtcttag ctgaagtttg aaaatcctga
    21721 atatgagtag cccaatatac tgatgtacca cctggaacaa caacactatc ataacaaatt
    21781 ggtgcatata caaaatgatg taatccagtt ggtattaaaa tcttttgtaa gaatgcataa
    21841 caccaaactc ctatatttcc actatttata aaaaacgttt gcaaatgtct aataacattt
    21901 tgaatatgag gccaaataaa acaagttaat aatgcaactg gtatcataac aaagaaacaa
    21961 attgcaacta caagtgatga gcctctaaat aatccaataa aatctggcag ttctttatca
    22021 taaaatctat tatgaatata aatgacaata cctgatatta acaaagcacc aaccatacca
    22081 gtatctaatg ttttaatacc agcaatgctt acaagtccac ttccagcact tatttcagct
    22141 gcgaaatcaa ctccaaagct ttttccccaa aaacttaaca tagaacctac aaaataatta
    22201 aaagtcaaat acgttgctaa agcctccata caagctcttg cttgttgctt ttttgcaagt
    22261 gctattggta aagaaatagc aaataataat ggcaattgat taaataccat ccaagctcca
    22321 ctagatatta caccccaaaa ttggtaccaa atattttctg gtgtagcaag tgaacccata
    22381 attgactgat tttgaaatac aattgagaat ccaaccatta tcccagcaaa agcaaataat
    22441 agtgttggtg taaacattgc ccctccaaaa cgctgtattt tcttcatcat ataaattact
    22501 cccctcctca tatttttagt ttatctttgg ccttagatat ctattatttt aacaggttaa
    22561 taaatatata caatctttag ggtacattcg gagcttattc acagtcaaat aagtttttgc
    22621 acatttttat gttcaaattc tcataaaaaa aaagaatgac tacaatttgc aatcaatccc
    22681 ttctgtaatc attctatgcc ttttataaat actatattta ataaataata actcaatcaa
    22741 tataaaatat aacattgtca atttataact agggtgcatt tgtaaaaatg agatattagt
    22801 cgctgaaata taaattgatt catcacttaa atcagtcaat gtattatttt taaactctgt
    22861 aattgaaatt attttagttc ctattaattt taatcttcta gcaatattaa gtgtattctc
    22921 attctcacca cttagggata taataatcat aacatcattt ttactgacaa tattgtaaaa
    22981 agaatcatca aatgttcttc cctcaaaatc atatattatt tcttgacatg ataagaacat
    23041 tctctttatc tgttttgcaa ccacattttg aatatcacct gaaccataag cgtatattgt
    23101 tcttgattca taaagaagtt tacacaatgc atcataatct ttattttttt gatcttcaac
    23161 atacttaatt attgaattac atgcaatatc aaatgactga ttttctatga catgaacctt
    23221 ttctgattcc cagcttaata atactttaaa ctcactgaaa ccttttaaat ctaatttttt
    23281 aacaaatctt gtaatagttg cacgagacac attacatttc atagcaagtt catttattga
    23341 catcttacta caatgttttt tatttgcagt tatatatttc catattaata aatctgtatc
    23401 attcaattta ttataattta aaaaaatcat ttcttctaat ctcataaact attaccccct
    23461 ttaattaaaa atcgtcataa atattatacc aatattcaac attaaattac agcgtattct
    23521 tatatttact atttagccca taaaattgac tataaaaaat actgctataa ttgatgttta
    23581 aaaaaatgta gttttaattt tattctttta tctaataatt aatattttca agttctagtg
    23641 cttttcttat acaattatca tctttaaaat cagcagtcct tttacaatct tttactttaa
    23701 attctggaat agttttaaat tcctcatcac atattccatt cttatttaaa tacatacaac
    23761 ttgccattct aactattaga ccactatttt ttaaattaaa caatacaggg tctatacacc
    23821 ctccatctcc gccagtagtt tcaccaacta aagtcgcaaa tttattttct ttacaaaaca
    23881 ttgcaaatga ctctgatgat gaatatattt ttctatcaac aagtaagtat atattaccct
    23941 taaattttga atcatctgta gattttatag tataggaagt atcttcaaaa tcattaaaat
    24001 cttttataat ttctttaggt gcattttcct ttacacttgc tggtaaattt tctacaggat
    24061 ttaattttat atttcttgca tttgtatatt tttttactat ttcattatta tttctataaa
    24121 ttctataacc atttattttg acatcatttt ttatgagttt agatacgatt ccctgccaat
    24181 acctatcact tccacctaaa ttacctctta tatcaataat taaagcttta tgtttttcta
    24241 aagtgttaat ataatctcca attattttta aatcattatt tatagagcca ttctttgatg
    24301 acattgatgg taaatacata tatccaatct gacccttaat aacatccttt aaaattaatt
    24361 ctttttttac aaaaatatca tctggcattt ttattttaag attcatagag tcatatctat
    24421 ccacaacttt tttatcatta agaaaatcat accaatcatt attagagtat gatttcttaa
    24481 aaagttcata tcttttctta ttatctatta cttctgtgtg tttattattt aaatcagata
    24541 atatagatga cagttcttct ataaattctt catcattttc agtgtttttt attcgttttg
    24601 tatattcatc cttatttgct aaccaatcaa tattattaag cctcttattt acacctagat
    24661 atggatatcc tgtctttaca acattataca cataattaaa gtcatccacc ttttcctctt
    24721 cagacaactg attcttttga gaataagtag aattacctaa taatattata aatgctaaaa
    24781 taattactaa aaataatact ttctttttca tgtaattctc atccactttc agattttata
    24841 ttttaataca ttgtatcatt attttattat cacctaaaca gttaaaagaa attcttgaag
    24901 atatattcca ctattattct atttaaaaat ttttatttgt attttcaaaa ttatttcatg
    24961 aaagttataa aataacaatt atattcaaat atctatttta ctgctatatc ctgaaagtaa
    25021 attcttatca gtgatatact aaaaaagata tgctaaaaaa tttatccatt ataatgactt
    25081 aaatttagat actttactga tttttattta ttagttgaga aagatattga taattaaaaa
    25141 tattgataac tatagaaatg attatttttt atagaaattt taaggatata aactaattat
    25201 acttaagtct atatccttaa tttatcatga ttatgagaat ttttacaaat acttatcttt
    25261 gtccgtttta gaataaaaac aagaacatat cctgttattt tattcaaaca tccaaattta
    25321 attactacac aattacttat tagaaattgt atctacttca tatatatatc tgttaagtat
    25381 agcttctagc atttcttgtc ttccagactt attctttata actggcattt gcagtgcata
    25441 agattctaac tctttaaatc caaccttacc ttctactata tccttaccta taccttcact
    25501 aaaacttgca tatctttctt tagtaaagtt ctcaaatacc tcatcttcta ataatttatg
    25561 agctattaat aatccctttg caaatgtatc cattcctgca atataagcta ggaataagtc
    25621 ttctacctca aaagatgctc ttcttacttt agagtcaaag ttaaatcctc ctggtgctat
    25681 tccaccttgc tttaacactt catacatagc aagtgttgca tcatatatat ttgttggaaa
    25741 ttggtctgta tcccaaccta ataataggtc tccttgattt gcatctatac tacctaaaac
    25801 attgtttatt cttgctatat ttaattcatg ttggaaagta tgtcctgcaa gtgttgcatg
    25861 gtttgcttct atattcattt tgaagtattt atccagatta tactttctta aaaatcctaa
    25921 aacagtagca gtatcaaaat cgtattgatg tttagtaggc tcttttggct taggctctat
    25981 taagaattgt ccagtgaatc ctatttcctt agcataatct acagccattt gtaagaatct
    26041 tgcaaagtta tccatttcaa gttctgtatt agtgttaagt aaagtttcat aaccttctct
    26101 tccaccccag aatacaaaat tttctcctcc taagtactta gttatttcca tagctttttt
    26161 aacctgagct gctgcatatg catatacatc tgcattacat gttgtagatg caccatgaac
    26221 aaatcttgga tttccaaaca tattggcagt tccccataat aactttatac ctgtcttttc
    26281 catattaact tttatatact caactatttc atctaatatc ttatttgtct cttctaaatt
    26341 tcttccttct ggtgctatat ctctgtcatg aaaacagaaa tactcaattc ccatcttaga
    26401 cataaattca aatcctgcat caactttaat ctttgctatc tcaattgggt ctgttatatt
    26461 attccaaggt ctctctactg tgcctactcc aaatgggtca ttaccctctc cacataaagt
    26521 atgccaatag ctcattgcaa atcttaagtg ttctttcata gtcttattac ctaccacttg
    26581 ttcaggattg tagtatctaa atgctaattc attgtcagat tttactcctt caaattttat
    26641 ctgtcctatt cctttaaata tttcactcat ttcatgtcct cctaatattt tacacatata
    26701 atatatgtag tatgttttct taatttaaaa ctattttcta tctttatttt tctttttaag
    26761 ctaatttaat tatttatttt tgcattaact acttcatcta ataacttaaa gttatctttc
    26821 aaagatttgt atattctttt atacaatcta tgatatatat tgtatgtatc tacattttca
    26881 cttattggtt ctaatttagt tgaagttttt attatagcat cacaagcttt ttgtatattt
    26941 tcatatattc cagctcctac taatgcaaga attgcaactc caagtgctgg tccttcactt
    27001 gaatttatag tatatacatc ttgattaaac atatctgctt gcatctgtct ccatacttta
    27061 ctttttccac ctccacctga ggctcttact tcattaacgt ctatattaag attctctatt
    27121 atatccatac agtctttaag actatatgaa acaccttcca ttattgacct tgcgatttct
    27181 tttttagaat ggattggaga taatccaaag aacacacctc ttgcataagg gtcaagatga
    27241 ggggttcttt ctcccatcat atatggtaag taaagcaatc cattacatcc tgttggtact
    27301 tgacttactt gattatttat aatctcatat acatcttcac ctaaagaatt tgaaacttcc
    27361 acttcacttt gacagaaatt atctttaaac cattttaatg acaagccagc tccttgagta
    27421 actcccataa catgccatgt atttggtatt gcatgacaga aagtatgaac tctaccttct
    27481 ttatcaattt ttggctcttt tgtataagca aatactacac ctgatgtacc tatagtagat
    27541 gaaactactc catctttaac tattccattt cctatagctc ctgctgcttg gtctccagct
    27601 cctcctacca ctattgttcc ttctttaagc cctgtcaaac ttgctacatc tctagtcaca
    27661 taacctgtaa tctcttgtga ttcataaact ttacctaaaa gatttttatc tatatttaac
    27721 ttttctagta cttcatcgct ccaatctctt tttcttatat cgagcaactg cataccactt
    27781 gcatctgata cctctgtagc atattcacct gtcaatttgt atcttatata atcttttgga
    27841 agaagtattt tattagtatt tttatatata tctggttcat tgtttctaac ccataatatc
    27901 tttgatgctg taaatcctgt aagtgctgga ttagcagtta tttcaatcag tctttcttca
    27961 cctactaaat cagttatctc ctcacactct tttactgttc gttggtcaca ccatattata
    28021 gagtttctca atgttttacc ttcattgtcc agcataacta gaccatgcat ctgtcctgat
    28081 aatccaattc cttttataca ttcactgctt atatttgaac tttgaactac ttctcttata
    28141 gattcgacta cagctttcca ccaatcattt gcatcctgct ctgcccaacc tgatttctct
    28201 tgtataagag gatattcata tgtacaactt tttatagtat ttcctagttt atcaaataaa
    28261 actgttttcg tacctgatgt accaatatcc acacctaata catactccaa cttcatccct
    28321 ccttgaatgc cacttcataa ctatcgtttt cctatcctaa tttttttata ttttaggtat
    28381 attttacttg ctttattttt gttagtatat taaactaact tatgaactaa taataaaata
    28441 tttaattatc tttgtcaatg caaaataacc ttttattttt gtgtaaaaag tattacaata
    28501 ttattttaag gaggaatatc aaattggtta ctgataaata cactattcga gaaatgaatg
    28561 aaagattggt acttgaacaa attataaaaa atggtcctat ttctagggca agtatagctt
    28621 ctactatagg attgaataaa gcaactatat ccgctattac caaaaaactt attgatgaat
    28681 ctctagttca tgaaatagga attggaaata gtactcatag tggcggaaga aaacccatat
    28741 tattagtatt taataaatgt gcaggtattt ctttaagtat ggacattgga tacgactata
    28801 tattttcttc tctatcttac ttagatggaa ctattataaa ttctaagaaa ttaacagata
    28861 tacaagtaag taaagacaat gttatacaat tgatagatga aattataaat agttataaca
    28921 tatccaaaat agacactcct tataaggtaa ttggtcttac tttggctata catgggatta
    28981 cttgtgaaaa taaagtattg tttactccat attacaatct taatgagatt gacttatata
    29041 gcatccttag caaaaagtat gactttccta ttcacataga aaatgaagca aacttaacag
    29101 ctttagctga gaatactttt tcaactgtac ataactcact acttagtctc agtattcaca
    29161 gtggatttgg ttcaggcatt ataataaata ataaattata tagtggcaga aatggtatga
    29221 gtggagaaat tggtcacact atcatcatgc ctaatggtaa actatgtcct tgtggaaatc
    29281 gtggctgttt agaacagtat tgttcagaaa aaaaggtatt tgaacagctt tcttctttag
    29341 aaaatattcc taaaatagat tctgatatag taaaacaact atattatgaa gataaccaga
    29401 atgccaaaaa aattattcat gagttttgta gttacttaac aatagctata aataatgcta
    29461 ttacaactta tgctcctgaa ataatatatt taaatagcca aataattagt gatatccctg
    29521 agatattaca gattacaaaa gatatgttag ttagctcttt taacaaagga ataaatatag
    29581 aaatttcatc attagggtct gaggcatctc tatatggtgg ctctgccgta aatatcaaga
    29641 gctttttgaa tatacaaaat ttaactttaa ttaatgaaat ataagggtta tgactatata
    29701 cagccataac cctttaaatt atacattcta aaattagatt tattatatag tttatgcaag
    29761 attagctata ttttttaaaa attgtatatc aattaagtat taacataagt atttcgtttt
    29821 aaatattaat ataatcttcc tactcatcat cagataataa acttgcattt tgttcaacca
    29881 tagaaatatt atctttacct attttctcta attttgctgc caattccttt gtatctaaaa
    29941 aagctgattc aataaccata cctaaattta gccctgaaat aattttaatt cgactgtcat
    30001 tattggctac taataaagca gcattgcatg gagttccacc tagtaaatct gccattataa
    30061 ttatttctga actttccttg tacacttcta aagctttttt taatttttct attgttcctt
    30121 ctattccatc atcttgtttc atatttacag taggataatc tatagaatcc cctattatca
    30181 tttttgcaga atttaagact tcttcagcca tattgccatg actcatcaaa ataatactat
    30241 tcaatttaat acacctcttt aaatctataa gatgtctaca agataagttt tcttatcatc
    30301 aggcgtcatt atagttgtaa tttcaattcc ttcatctaaa agtcttttaa atgcttcttt
    30361 ctcttcttca gtaacactga tattaggtct tagaactgtt gtatcttttc tacttgacat
    30421 atttcctaca tttatattat gtattttaaa tcctgcctct acaaatggaa taaggtccac
    30481 aggagactta acaattaata atacattttg tccttcatac tttcctgcag taatattttt
    30541 tatagcagtc tcttctgtaa ttatagatga cgctatacct gcaggtgtag ccattcttaa
    30601 aacttgtttt tgaacagaat tgttagctac tgcatcattt actaccatta atcttgtaac
    30661 acccaattta ttactccaca tagttgcaac ttgaccatgg attaaacggt catctatacg
    30721 aatattttta atacctttca tttccatatc taatatcatc ctttccttat tttaaaatac
    30781 ctaatgcata taaaattatt gaaacaacca ttactcctaa aattaagtat ataggtttta
    30841 tattcttttt aagagcccaa taaacaatca caactaaaat tgcaggaact aacccaggca
    30901 taatttggtc taatatttct tgacctttca ttgtaaaatc accttgttga aagttcaaag
    30961 caacattagc ttttacaact gaaggtatta atgcacctac aaccattaaa cctaaaatag
    31021 atgtactctc agttaaaatc tttaaacttt tttcaattga agatattagc ttagtacctg
    31081 atgtataacc agcattaaat agtggtatac ttaataattt caatgctaca ctcactacaa
    31141 tccacagtaa gattccaaat ggacttccat ctatcgccat attagctgct atagctccaa
    31201 aaattgtcca cggaataacg acaaataaac tatctcctaa acctgctact ggtcccatca
    31261 agcctgtttt aattgaagca acagcctctt cagtctcttc acttgataac tcctccattg
    31321 ctacattaat acccaaaata taaggggcaa cccaaggatt agtgttaaaa aattgtaaat
    31381 gatttaatac agcactttgt aacttttctg gattatcttt gtatactact tttaaaaaag
    31441 gtagtactgc ataacagtat gccaaggcct gcatcttctc ataatttgaa gaaacagaac
    31501 tagtaaaaaa ccagcgccat aagacacttt ttttcacctt ttcatttgat ttatttaatg
    31561 ataccttatc actcatcttc gtccatacct cctactacag tatattgttg ttcttgattt
    31621 tccaaattct ttttgtaaat tataagtgca attgctccac caattaaagc tacacctaat
    31681 aatggtactt tcatatatac tgctaaaaca aaaccaatta ctaagtaact aaaatactcc
    31741 ttagcaggaa gatatctaag taataatcct atccctactg ctggaagtag tcctccagct
    31801 actgttaaac cacctgttaa ccattcaggt gtatatttca aaatggtatt aattaaagaa
    31861 ggtccaaata ttacagatag agcaactgga atacctgttg tagctgctgt taatagtact
    31921 cctaacattt gcatataggt tatattttta taatttcctt ttttagctcc atcttctgct
    31981 ttatgaacta gccatatacc aatagtattt ctaagaacat ctaattgtac catcaataaa
    32041 gcaactggaa tacctataga gattcctaca gatgcttctt gcttagtcgt aatagttata
    32101 aatgtggcta ctatacttgc tgtttgataa tcaggtattg atgctccacc aaagttacta
    32161 atacctaatg ataatagctg taatgtacct ccaatatata accctgtatt tatatctcct
    32221 aagataagac cagtaataaa acctgctgtt actggttgat atgttccaaa cattgttgaa
    32281 tttttttcat agtttataaa aaatccatat agtacgatta ataataattg ccataattgt
    32341 ggctccatta tgatttcacc tctcccaaaa tattttttag ttctttaaaa ttataactgg
    32401 aatcttgctt taggaaaata ggaatttctt ccagtgggca ttcaacttca taagttttcc
    32461 caccttcata actaactcca ctaaatatat tttcccatgt atgtcctttt ggtaaatata
    32521 cttttctact tctatcttta taattcatta ttggagctac taaaatttca tctccaagca
    32581 tatatgtatt atccacctcc caagttttat catcttcagg aaattcataa aataaagttc
    32641 tcataactgg tgttccatct tcatgcgctt ctttcatcag tttttttaaa taagttttta
    32701 agctctctct aatttttatg aattttgtaa gaattacttc aacttcttca ccataagacc
    32761 atatttcatt aggagctcca gttaccattg agcctccacc tttatttgat aatggtttac
    32821 tatgaggcaa tctatctcca tgcattctca aaattggtga aaaagtagca tattggaacc
    32881 atcttaccat aagttctcta aattctgggt ctttaggatt tcctccatgg aaacctccaa
    32941 tatcagtagt ccaccatggt atacctgcca gtcccatatt taaccctgta tttacttgat
    33001 tattaaaagc ttcaaaacta gaatcaatgt caccagacca tactaaagct ccatactttt
    33061 gagctcctgc ccaagctcct cttacaagag ttacaacaga ctctatgtca ttatgtaaac
    33121 catcataaat catttttaaa taatcaatag gataaatatt accacaactt aaaacatttc
    33181 cttttttata tctatagtta tcaaaatcat acacagaata gccaggttca gctacatcta
    33241 accaataata gtcaatccca agttgtttat aatttttatc tattctatcc caaacatatt
    33301 ctcttgcatt ttcatttgtc atatctacaa agactgtatt tccttgaatt tgcattgtca
    33361 ttctaacacc acgattaaca ttgactaaat agccattttc taaataatca ttgtagtttt
    33421 ctgcatcact ttgaactgta ggccatacag atactattgg ttctactgaa tactcttctt
    33481 tcaatttttt aactaattct ttaggatttt tccaataatc taagtcaaat ttatattcac
    33541 cttgcttagg ccaatgaaaa tagtcaattg caattgatga aagcttaatt cctcttttag
    33601 aatattcctt cacaacatct aaaacttctt ctgaagttct atatcttagt ttactttgcc
    33661 atagtcctaa aaggttttca ggcatcatag gaacagttcc agtaacttga gaataatttt
    33721 tatttaactc ttttgggctt tctccacaag taatccaata atctataaaa tttgtagaaa
    33781 acatcttcca ttctgtcata tttttagcaa aagatacttt tccaattccc ggattattcc
    33841 ataaaagtcc ataacctaga ctagaaatat aaaaaggaac tgatatttga gaatttcttt
    33901 gggctaactc caaaacagta ttctttaaat ctaaaaattt atgttgatat tgtcccattc
    33961 caaaaatctt ttcagaaggc tcagattcaa atctagtagt tacttcaaat tctccactat
    34021 agcttggtcg atattctctt gattttaact ttagagtaga gttaaagtct ttggtaatct
    34081 caattgtccc tacatcttct ccaccatcat catgttttac agctcttaat cgaatatatt
    34141 ctttcaataa tatttcattt ttatcattat aaaaagtaat tctatctcta tggtctaaga
    34201 cagcttttat ctttccattt ttaatgattg cacttccatc ttcattttta ttaattgtaa
    34261 tatcatcttt atttaactta ggtttttcgt taagagcata gttttcatca acaaaatttt
    34321 ggtctacaaa cgacctaata cgtaaagagt tttttcccca tgcttctatt cgcaatagtt
    34381 cattgtcaaa tcttttttca atatagtctt cagatatttt tatcacggct acctcctaaa
    34441 tcaatggtat aatattctat ctttgtgtag cttaagttaa ataatgtcgt ttagtatcgt
    34501 tatttataaa ttaggtttta tatataattc atttgtacat taaactaact taccaataat
    34561 atactttatt tgactttgtt tgtcaatcgc tttccggatt ttagtaaaat tttctaatat
    34621 gttgcttgaa agtcgttctt aatatctttt atttatactt ttaatatctg tgatgatacc
    34681 tatatacatc tagttttttt aaaacacata caggaataaa gtttgcctat tatgtagata
    34741 atatcggact tgaaaatatg tatagtgacc ttataaatac agataataat atattagata
    34801 ttgttcaaaa caatggattt tataattata aataatttat taaattattt aagaaaatat
    34861 acaattgtat accaagtcaa aaacgacaac aaataaataa aactaaaaaa gatgttgtct
    34921 caaaatatag ataaatttat ttttcattgc taaaatgatt aaaatatatt tgatttaata
    34981 tacttgattt aatataaaaa aagagtgtct cataaactaa aaagttcact tttagacact
    35041 cctttatata tattatctac ttcttaattc atttattacc tctctacatt ttctttcaac
    35101 tagtggatac atctttataa gtactaatta ctccacttaa aaatgattca ggtactgtcc
    35161 atcagtcata tttttctgcc aaatataatg gtgtttcata atgagacaat aaatatttat
    35221 atctctactt atcttctcta agctcgtcaa atccaactat aggtatattt aaattatatt
    35281 ctttaagtag cttttctagc tcttctataa aaataccttt cccatccacc atttgtatat
    35341 cctttatttt atccatcaat tcattgcaac cacttaactc accaaaccaa cgtttagaac
    35401 tacatgtctt attataacca caacttggac tgccatctat tgcaatgata ctttttatat
    35461 cataatcatt ttttaaatat tcatcaaact gccttacatg aggtattaac atttgcctac
    35521 attgttctct aaaaaacaaa ttgtcaaact gttcttttac atgtccccac ctatttattc
    35581 catacataat catttctgga catggtagtt gaattattcc atacccttta tttattaaat
    35641 ctattgctat attttgtgct cccttaaatt ctgacaatcc ctctacttta gaattacaat
    35701 ttaatataca atgacatact actacaatct ctctatttct cttcataata atctccttag
    35761 ttattcttaa ttttaatgat actacatatt ttgataatta tattatttat ttgttctata
    35821 tttccaatat tctatataga aatatacaat tagtaatctt ttataatcta tactatgata
    35881 aatgtatata tttttttagg aggtattata attggatact aaaaaagtca cattttcttc
    35941 aatgtgcata gttattaata ttgtcttagg tatggttata tctatgataa atataccatt
    36001 attattttta gatacagttg gtactgtact tggggctgtc gtattaggtc ctttttgggg
    36061 tgctcttatt ggtgggtgta caaacttagt tttaggtgtt atatcaggtc ctacaaatat
    36121 accttttgct cttgtaaata ttgttcttgg tcttattgtt ggatatattt ctaagaaaaa
    36181 aggttttggt tataaagaag ctattattac aggagtaatt ttatctattg tttgtccttt
    36241 aattggtact cctatttcag ttttattgtt tggtggttta agtggaagtg gtgctgattt
    36301 attggttggt tttttagttc agtctggtca gaagatattt actgctgcgt tctttccaag
    36361 gattcttagt aatatagtag acaaaccttt gtcttgtatt atggtggtat attttataag
    36421 taaaatgcct aaaggtttta taaaacaata tagtaaaaat acttctagtt catattaata
    36481 aatcatttat tatgtaaggt ttattactct ttaaaatgct atatactcat ttttatataa
    36541 catttttatt aataatttaa ttagatagta tttgtattac tttaattaaa cgtaacctct
    36601 tgatataaat ttgagctata aatctatatc aagaggtgct attttatttt taatataatt
    36661 aatattctat tacgcaaaaa atgcatatat ttcattattt tatggaaaat attacttcat
    36721 ttaactctat atcaaactca ttaagtaaaa atctaattat atttaattta gcctctgtat
    36781 ttaaatttgt ttctaaatat atattttctg atattttaat accttttctt aatttatatg
    36841 catctctaga cttaatatta tctataaaat ctcttttata agttttgtct acaatactgt
    36901 taaaccttac agaatccaaa tcatataaag taagagcaac ttgttcataa aattctgtcc
    36961 aatttttagc cttatatgac tctcctaata tactaaatga tactatactt tcatttgtaa
    37021 aattaacatc atcatcctct aacgtaaata tattttcact gttacttgga ggttcatatg
    37081 taacacttgg atatttccaa atttctacag ctctatctag taatatctta gttctatttt
    37141 ttatttcttc ttcattccac ttatctatag atgaaatata tttatttaga taaagtctac
    37201 tatctttaaa tccatcttcc atttctttct tttcttcaaa tgttttatta cttagttttg
    37261 aattatatcc tgtcaaagtt aaatttccaa ttgtatgtaa atatttatca tgtatctcct
    37321 tatagttatc tcctagtgat tccttccatt tatttgttaa tgtctgtggc attatatgct
    37381 ctatatttag catattatta ttgattaaat tttctaaatc aacaatttct ttattattat
    37441 aattctctaa cctctcaagt atatataact tattctttga cttagtatta tatatatctt
    37501 tagtttcaaa agcatttgaa aattcactgt cagtaggaaa tctttgagat gatttcttat
    37561 ttataaaaat atatcttaat atattagaat agttttcttt ataatcacta aattttttaa
    37621 tttcccttcc taagttcata aatactttat tcagtgcatt aggaggtaca tcacatacta
    37681 ttcttcttaa tataaaacat tctactaaat taagggattc tacaagtact tttttattta
    37741 ttataccttc attataatca tcaaataatt ctaatataaa cggatatgat acaaatattt
    37801 caagtttgtt tatccttttc aaaactttgt ttacatcatt atcatcagta catgaataag
    37861 atatctctct ataatagtta gaaaatttaa gtaaatcttt taataaaatt tctatatcta
    37921 taccattatc tgatacatac cttttaaaac taaaatatac tttattttta ttcggtatac
    37981 ttctctcctt tatagtcaaa tagtctctta taaaactact tacgttgcta cttgtatttt
    38041 tttcaatttt ataccaataa ttattataaa attcctcttg taacttagag cttctaccca
    38101 ttaacacaaa gtttcttact ctatcagctt cacttaaatc taagccagtt gaatttagac
    38161 tttcaaagat taattgaggg tcatcttcac cattttttaa ctctatttct actatagtta
    38221 atttctgtat agcatcaaac aaatcatcta ttgatatatt atcttctttt attctattat
    38281 aaaaatataa ataatttgaa actatattag aatttctatc tgtattcatt tcttcttcaa
    38341 atagttcata gtacgctttt ctatcttctg ctattggttt taactttatt tttccatctt
    38401 tatctcttga gtgcttgttt ataagataac actccttaat ctgttcttct gttgtaataa
    38461 ttccttttga ttccccaaac tcttttatta tttgacacat ggcaatcaat aatattgaca
    38521 cagtagtcac tctttgttgt ccatctatta ttaaatattc ttttcccata ctatatatag
    38581 atacaactga ccctaagaaa tgagttctaa atccagaatc tattatatcc tctaaatcat
    38641 caaacaatct tttacattgt tctttcttcc agttataatt tctttgatat acaggcacta
    38701 caaaactttt gtttgacccc tctaaataac taagaaattc aatttctcct gctttcatat
    38761 taactccccc tataagttaa ataaattcca ttcataactc catgtatcta tatattatat
    38821 caaaattttg actcataaat gtatatgaaa gccttattat ataccttttt atacctattt
    38881 ttattttatt aaagtaaata catgattatt ctataaaata tacaaatact taattttaaa
    38941 aattattatt taatcttctt catgagtaat tcatagttat ttatcaatta aaaagagata
    39001 ttgcataatt attcaatacc tctctttgta tatttacatt atccatatct agttatctat
    39061 ttcaacccaa tattagacta cctactaata aatttattct ctacatcatt aacaataatt
    39121 tttcactaaa taacatcatt agcctatctc tgatgcattt tctttaattt tatttatagt
    39181 tttaatcaat ttatttctct cttcaatatg attttcaaat aaatcaatta tacttccaac
    39241 agttctaaat gggtcttcca tcaacacttt gttatcctct ataaatccat tcttgactac
    39301 ataatcgact ataagtttaa caaaatgtat ttgcttagta ttaaagctct tattatttaa
    39361 aaactctgaa aaagcttcat ttgcagcttc tctatccaat cccactagtt ttctcactaa
    39421 ttgacttact ggagtatctc caaactcctt cttataatca tcacaattac ctaactgttt
    39481 taagagtatt tcctccaacg tttcaacatc ttgctttgtt atctttttat tatttcttaa
    39541 tttaaatatt gctaattcat ctttatggct atttaaataa tactctacct tctttttata
    39601 attcttaaga ttgtttgcat tatatacaga atcatttcta tcttctgcta caatcatatc
    39661 ttcaaaactt gtataatata tcttttgact agacttttca agatacttaa taagctctct
    39721 taatgatata cgtacttctt ctacctcaaa tatatctgaa tcttcccaaa aatcctctgt
    39781 cattgctttt tcaatagtat atttttgttg ctgaatctgt ggtatagtcc caagttttga
    39841 aagtttttct gctgtagcca ttacatgcct tataccttta cttgcattat tattttgtaa
    39901 gtatgcaagt tgtatattat acataactac atcaaatctt ttagccaatt catcatcact
    39961 atatgaagtt atgagtggtg atatatattc tcttatctca ttttgtgcta ctgctccaat
    40021 attgctccaa acattttcat ttttatactt atgtacataa cttaaattca tcctaactat
    40081 ataactatcc tcatttaaag cttttacaga agttataagt tcttctaaca attcttttct
    40141 aagttctgca tactcacctt ctatatattt aatatcttga agttctttaa ccatacttac
    40201 ctttatatta aataattttt cagtaagtgt ttctgtttta tttccctcaa atcctttagg
    40261 attaaattta aaaaattcaa aattattaca aaaatcaaat attaagaatc tttccttatc
    40321 catatcaaca cctaataaat ctggacataa tctagttcct ctacctatca tttgccaaaa
    40381 cttagtctta cttctcactt tcttgaaaaa aacaagattt agtatttcag gtatgtcaat
    40441 tcctgtatca agcatatcta ctgaaactgc tatttgaggt aatttattct tatcagaaaa
    40501 atcatctatt atagaatcta cataatttat actatagtca actgctttta caaagttccc
    40561 accatacttt ggatacagtt tattaaatct ttcaactatt gccctagcat gctttgtatt
    40621 ctttgcaaaa attatagtct taccaatctt ttcttctcct tctattttca acccctctgt
    40681 cattagctta tttaaaacta aatctattgt gtcagaatta aatagccact catttactgc
    40741 attattccct atttcgtctc caatactctc atcatcatta aatgtatttt catattcttc
    40801 cttctcttca tcagaaagct catcatactt aattccatct tccataatct tagtcttaaa
    40861 ctcaatacta gtataatcta ctaaatatcc atcctcgact gccttattat actcataagc
    40921 atatgtaggt actccatttt ccatgtcaaa aactgaataa gtatttttat ctatctcatc
    40981 ctttggtgta gcagtaagac ccattaagta agaatcaaaa taatcaaaga ttgacttata
    41041 ctttttataa atacttctat gcgattcatc tattataatt aaatcaaaat gaccaggtgt
    41101 aaacaatctc tttccatcct tagacttcgt atcatcaatt gcattcatca ttgttggata
    41161 tgtagaaaat atcatcctag catcttctgg gctatctttg ctatccaata aattacataa
    41221 cgccaagtta ggtaatagct tagtaaaact ttttttagct tgctttacca atgcttttct
    41281 atctgctaga aataatatat ttttaatcca attatgtctt gaaagtacat caactataga
    41341 tatagcaatt cttgtttttc ctgtaccagt agcacatacc aaaagagttt tgcgttgctt
    41401 attttcaaga gcctcacata cagccctaat agcttctttt tgataatatc tattggatat
    41461 ttcatcattt attgttacag aagttaaaga cttcttactc tttcttctat ctatcataag
    41521 ttgtaattct gattttttat aaaatccata aactttccta tctgaatagt catcccaaat
    41581 atacatatca aaaccattag tcaaaaatat taccggtctt tgactatatc tcttttccaa
    41641 acaatctgca tataatttag cttgttgttg accaattttc gggtctttac tcgttctttt
    41701 cgcctcaact actgctaatg gcttaccatt ttcaccataa agaacataat ctacatatcc
    41761 tacaccactt tcattagaca taccttgtac ttctatttct tcccatatat cttttccaaa
    41821 ttcccaacct gcaagcttta attctatatt tatatatctt tttcttgtct caaattcgct
    41881 tacttcgtct atcttgaaat catagtttgc agtattaact tttctctttt cagttagtga
    41941 ctttcttaat tcctcatttt cttttattac ttcttcaagc tttttatctt ttgaacttaa
    42001 tctctcataa agatttttaa gttcgtctgg tctcgtcctt ttctcttccc catgaagtaa
    42061 taaatcttca ttaaagtctt ctgctgtata ttcatctgaa taacaatagt ctatccaact
    42121 aacaaattga tgcaaattgt taagtgaaag tattgcttct cctctctcta tgttcgcact
    42181 agtatgtaca gataaattac ctaatttaac tatatatttt aataaaggta acatatcata
    42241 gtctataagt tctataaaac tattattatg aatcaacgta ctaagattat cttgataagg
    42301 caataataaa tcactatcat tagtatatag ccattttact gcaagctcta aagctcttct
    42361 tgttatagtt gcacaagtag atgggctaac tagtatactt ttttctgctt ctaagcaagc
    42421 agtattaaaa ctattgaaat ttttcttctt ttgtaaaaaa tcaaaattac ccaaggcttt
    42481 tctccccctt ttgtccctta gttaaaataa atctctctaa aaactatttc ttacagctgt
    42541 ttcttatact aacaaatact tcttcatttt ctgtaaacaa ttcgtacata tcttcaaact
    42601 gtggtatatc atatccatga gaatcatcat ttctcaattt tctaagtgtt tctataacta
    42661 tagaagaatt tttaggtaat aaattgtgat actcacaagt taaaaggtgg tcataaaagt
    42721 ttttagattt tatatttaaa tcaattgatt tataatacaa cattgctttt gttaattcta
    42781 gaaatgatac catatagctt ttaaagcctt cttttatgta tctagcccat aactcaggca
    42841 tttcttcctt atcatataag attttgaagt tttgcaggtc atacaagcaa gaaccaaaat
    42901 ccctatttac ttcttctatt gagttccaag ataatttgtt tctaattacc atacatgtcc
    42961 ctccaatcta agatatctat tacatcactg ttttcaaaat agaatttatt tatataatcc
    43021 ttaaaatctt tagattcata aataacttta ccttctaaaa tagctttttt aagtgctatt
    43081 gtataattat ctgtaacaat ttttaggtct acatcaatgt ctaatatatt tcttagagct
    43141 tttgtcttag ttgcaagttc tgtaattggt acttttttga taggaatcca agctatgtct
    43201 atatcacttt ctgatgtatg tttatctgtt ccataactac caaatattat gattgctaga
    43261 gtattttctt ttggaaatac atttattatt gagtttttaa tctcatttgg tatatttctc
    43321 atttaatcac ctcttgttta ttaggtaata ttgcttaatt gaatttatat ccataatctt
    43381 ttaatctatt tatacatatt tctctttctt catcagtaaa caactcttta tacttttctt
    43441 ttaatactaa tacttctaat gataaatcta atctcttaca ctcccatagc cttgtaaatc
    43501 cttcagtagc tccttcttta ttgattaatt ctttagcagc taataaggct cctttgttat
    43561 ttatcagttg taaaaatctt gttagcttat agttacattg taaatcagct tctttataga
    43621 tatttaccat gtcatgatat aaatctagct ctatttgatt catagatttt attcccccat
    43681 tttaatactt gtattttagt tgaataactc tcctttaaaa gctttttgca ttaatgagtt
    43741 aaagttgttt tctagttctt ttaagctatc ttccattctt gatttcaatt tgtctatttg
    43801 tctgacaaag tccacaaact tattttgaag atatacaggt actttaggta tttcaacttc
    43861 atttaatttg cctactgtaa gacctggttg tgctgctcca gttgataatc gatttaaatc
    43921 taactcttta agtgtaaaat atagccagta actatttata tcaactttag gttgtactac
    43981 aactgcatgt tctgtagcat aaaactttcc atttacatat tttacattac cacataatgc
    44041 tccttgccta cctatgagat taaatgttcc cttatgtgaa tacattttta catatcccct
    44101 taaaccattt cctccataac aaggatataa ttcatgtgaa tttttttcat aaatatcttt
    44161 tgcttttata ttttttccag cttttaagtt tgatatctct cctaataact ctgtatccca
    44221 atctttacta ttagtaatca catttccaaa catctcaata aatcttgatt taactaattc
    44281 atccaatgct tctatttgct cttttctttt atttattaac tcttgagctt tatttaaaac
    44341 ttttaccatt ttattttgta tacaaattgt gaaatatggt atttttatat catttaactt
    44401 gcttttattt aaagttgcac ccataactgc tctatcagta ttattaaaat ttaaagttct
    44461 caaagcataa tataaatatt cagatgttat aagttcatta ttttttattt gaaagttagc
    44521 aattgcttca tttgtaaaca tgtcttcttt taatatggca actctaccta tagacaactt
    44581 aaaactcatt acaacggtat ttttaggtac taatttcata ttagcttttt caacagctaa
    44641 atctgttatc tcttcttttg attttgatat atatttttct ttcaaatcag aaattgataa
    44701 ccatctatta ccacttcccc aataatcaga agtatttcta gatggtgttt tgccaatatt
    44761 tatatagcac aattcattta attttatata ctccataccc tatacctcta acattctttc
    44821 taattcttct aatccaacag ctatttcctt ctctaactcc ctaactctac ctataatcac
    44881 actaggagca tcataaacta cttcctcata cactacctct ttatacttat taatagataa
    44941 atcataccca ttctctctta tctcttccac atcaacaaaa aagctttgct ctgttctttt
    45001 tctatctact tcaccatcaa gattatcaaa tctcttaata atatcctcta tatcactatc
    45061 ctttatctca tttctcttat catccaaaga ataaccatca gctttcatat catagaacca
    45121 taccttatca gttccacctg ttcctgtttt agtaaatatc attatagctg tagatactcc
    45181 tgcataaggc ttaaacactc cacttggcat tgatattata gcttccaatt tatgattatc
    45241 aactatttct tttcttatcg atttatgtcc acctgttgaa ccaaacaata ctccatctgg
    45301 cactatacat gcgcatcttc caccaatttt taaaactctt aaaaaaagtg ccaagaataa
    45361 taactctgtt ttctttgtct tagtcacttt taataaatct gctgacactg cttcataatc
    45421 taaacttccc ttaaaaggag gatttgctaa caccaatgta aacttatctt tatctgtatt
    45481 aacctccgat aaagaatcct tatactctat attaggattg tcaacgccat gcaacatcat
    45541 attcatagca cctattctaa gcatagttct atccatatca aatccataga acataccatt
    45601 attaaaatgc tccttcagcc cttgcactaa gaaaagactt gaatgattat cccttaagta
    45661 ttgttgtgat gatactaaaa aacctgctga acctgctgcc gggtctacta taatatcttc
    45721 tggtgttggt ttaataagtc ttactatcat atctattatg tgtcttggag tcctaaattg
    45781 accattagta cctgctgtag ccactttgga taataaatac tcatacaaat ctccctttgt
    45841 atctctatcc ttacttaatt ctaaattact aataccatca actattttag ataacataag
    45901 aggtgtagga attttaaata ttgcatctcc catgtacttt gcataagctg agtctttatt
    45961 tccatgtaat ttttttatga aaggaaacac ttcattttgt actatttcat acattttttc
    46021 tgaatttcct tcattagaaa acttactcca tcttaaatgt tgatgttcat catcaaatat
    46081 cctttcaaaa gaaactccca aaagagttgc ttctgcttca ttttttgttt ctacttcatc
    46141 caatccttta ataaataaaa gatatgtaaa ttgttctata acttctaatg gattagttaa
    46201 tccaccagtc caaaatgtct cccaaatctt gtctactttg ctccttaatt ctcctgtaat
    46261 catatatgac tttccctcca gtgttcataa aataatttaa atatatattt tagtcgtacg
    46321 ccttaataat tagtgtctta tattaaattc aaaattttac tacacagtta ttaaattatt
    46381 tttcctattt acatgtttta gttaaaaaac taatgcaata ctcttatttt atgattatta
    46441 tacatcccat acaaaattat tttatcatat atccagcata gaagtcatct acctggataa
    46501 ctcttaccat attataactt tttaatatta atttaaactt agaaagaaat tttttattta
    46561 attatatcat cttccttatt tcaaatttct caattacaat ctcaatcaaa aaataaaata
    46621 agatgctgtc tcaaaataga tataatcttc ttttttattt tcggaatgat gaaaatatat
    46681 ttaatttcat acaaaaaaga gtgcctcctg aactaaaaag ttcattttga gacacccctt
    46741 aatttaatct tacttattct ctccctttat tattaacact tcactatctc tattgctttt
    46801 cctacacatc cacaaacttc catcctactc ttaacaaaat ctttaactga ctctaaacct
    46861 tttttaccat atttcttagg gtcaattacc tctgggtcag aattaagcac atccttaacc
    46921 ccattgctat aagcaatcct taattcagtt gcataattaa ccttgcaaat ccctcttttt
    46981 atagattcct taataacttc atctggtatt ccagacccac catgtaatac taatggaact
    47041 gatacaacat ctctaatttc agataatcta tctaaatcaa gctttggctc tcccttatat
    47101 aatccatgtg ccgtacctat tgctactgct aaagatgata cccctgttct ctctacaaac
    47161 tcttttgctt ctaatgggtc tgtatatgct cccccatcac caccatctaa atcgtcttcc
    47221 ttacctccaa ctttacctaa ttcagcttca acaggtatat ctgaaggcat acatgcatct
    47281 acaacagatt tagatattga aatattatct tcataacttt catgagaacc atcaatcata
    47341 atagaagtat atccaactct aagtgcctgc atagctagtc caaagcttga accatggtct
    47401 aagtgcattg ctactggaac acttgccttc tctgatgcta cctttacatt cgctaaataa
    47461 taatctagtc ctgcatactt tattgttgaa ggtgttgttt gcaatattac tggtgattta
    47521 agttcttcag cagcctctat tactgccata accatctcca tattttcaac attaaatgca
    47581 cctactgcat aatgcccttc ttgtgcatct aataatattt gtttagttgt cactaatgcc
    47641 ataatttctc ctcctatatg tttatactga tttaatttct tcgttattta attttgatac
    47701 tatttctcta cttgttttgc tatttaataa ctcatttaaa aattcttcat tcattaattt
    47761 tgaagatagt tgagataatg tttttaagtg taaattatca ccattatctg tagctgctat
    47821 cataaatata atatgtgcca agcttccatc ttctgattca aagtcaaacc ctttttttga
    47881 tacacctact gctacacgtg gtacctttac tgcatctgtt tttgcatgtg gtatcgctat
    47941 ccccatacca aaacctgtag atgatatttc ttctctttta aggatttctt ctttaaactt
    48001 ctttttatct aaaagaacac cagatttatc aagtattcca atcatttcat caattacatc
    48061 tgttttattt tttcccttaa catctaaaat tactgtttct tcgctatata aagagatatt
    48121 attagatacg ttttccgatt ctgcactttc atttttatgt tcatcttttg ttgcatttgt
    48181 attttctata gtatttttct catttactac tttaggtgta accatcatat aaagtacagc
    48241 acctactaat gaacctacaa atatacaccc tacccataaa agtggcttat tgactaatcc
    48301 tagaaccaaa aaccctccat gtggagctgg tacttctatt ttcattatat aagttaaaat
    48361 tgatgatatt gatgatgcaa tcataagtac tggcaacact tttaatggat tttttgctgc
    48421 aaaaggtatt gccccctctg ttatatgagt actacctagt atataattga ttaatcctgc
    48481 tgctctatct tcttctgtaa atctattttt aaataaagta gatgctattg ctattaccaa
    48541 tggtggtgtt atacaagctg cagatacacc tgccataaat aaataatttc cctgtcctag
    48601 aagcatagtt ccagttacat atgctgcttt atttactgga cctcccatat caaatgctga
    48661 catacatcct attactattc ccaaaattat agggcttgaa ttttgtaacc ccgatagaaa
    48721 gttcatcata gcattgttaa gtgctgaaca tggcccacca agtaacaaca ttgctacacc
    48781 cacaagacct acgctgacaa taggaattat aaaaatcgat ttaagacctt ctaattgtcg
    48841 tggtaatttt cttaacaaat gtacaaatag tttaactaag taacctgcta aaaatcctga
    48901 tatgattcca cctaaaaacc ccgaacctgt atcaaatgat atcattcctc caacaagtcc
    48961 tgccaacata ccagctcttc ccgatataga ttgagctata aatgctgcca atacaggaac
    49021 catcaagttc atagaatatc caccaacaga ttttaatgta gctgctattt gattatattg
    49081 ttctgaattt gggtcaaatg aataaatccc ccataaaaat gatatagcag taagtactcc
    49141 acctgctact actaaaggta acatgtgaga tacaccattc attaaatctt tatacaactt
    49201 ttgaccaaac gataaacttc cttcttctgc aattttactg cttgataagt ttccttttct
    49261 aatagctact tttccatcaa tacatctttg tataagttca ttagctttat gtataccttc
    49321 tttgacaggt acttctatta ccggctttcc attgaatctg tccatatcaa catttttatc
    49381 acaagcaact attattgcat ctgccatttc gatatctttt gctgttaact tattttctac
    49441 acctatagct ccattcgttt caacttttat gtcacaccct aattccctgg ctgaattttt
    49501 taatgcttct tctgccataa aagtatgagc tattccagtt ggacaacctg ttacccctag
    49561 aatcattttc tttcccattt ttataccacc tttctgactc ttatattttt tatataatct
    49621 tccacattct ccaaattacc tataccatta ctttcagcca cacttgctcc tgttgctgct
    49681 gaccttttta atgcttcttc aatatgttct ggattttcca gccatatact taaaaaagca
    49741 gctaatgcag aatcaccagc acatgcagag ctgactactg taactggttg agcactagca
    49801 taataaattg attttccatt ataaaaataa gagccttttt ctcctaaagt tagcaatata
    49861 ttttgagcac cttttaaatg tagtaattta agtacatcct taatatcttc ttcatctctt
    49921 acaataattc caaatatatc tttgatttct tcatcatttg gttttatcaa atatggatta
    49981 tactgtagta actcctttaa ttttggtgaa cttatatcga gtattgtctt tatactttta
    50041 tttttacaaa ttttaaatat atcctcatag taattatcat caataccagg aggtagactt
    50101 ccacttattg ataagtaact tatatcttct aatgactgta tcttatctag catatctagt
    50161 ttttgttttt cgtttacata tgacccagag tttacaaatt taaattcatc acttccatca
    50221 tttaaaaata tatttatacg agttgtatct tctacccaag taggcaatac gtcaaatcct
    50281 ctcttttcgc tttcttcaac tatatatttt cctgaaaatc ctccaaaaaa tcctaatatc
    50341 ttagattcta taccataatg acctagtaca aaagttacat ttaatccctt tccattagga
    50401 gaatatacag catttgatgt acgatttact aattttctct ttatcccatt agtagatata
    50461 ttcatatcta ttgcaggatt cgtagttaat gtatatatca ttgtcttccc ccttgctcgt
    50521 gctgtgtatg ttttcattat aataaaaaag tctatgaaaa tcttttcaca aatagaaaat
    50581 cgattttcat agacttttca atttaatttt cagaattatt atatctgacc atataatcta
    50641 taattatcct agatataata tacaagggca atctggaaga tacttcatat tcagaaattg
    50701 atatatgttc atgtttgtat cctacaatat ataaatccga atactttata agttttgcac
    50761 tttcactaca acagcaagtt ataaccttag ctccaactaa attggcattc tgtgctgatt
    50821 ctacaagctc tatggtattt ccattcaatg aaaatataat tataagttcg tcttttttta
    50881 ttgatttaga ttttattttc attatgttgg ggtcatttat aaaaacaaca ttaaaatcaa
    50941 gtaattgcaa tttaagacta aactcttttg ctacatattc agtaagccct cttgccaaaa
    51001 tatatatctt actagattta tttatagttt ttattatatt gattagtgta gttaaagata
    51061 tttgttctat aactctctgt gcttctataa aggatttatt tattatatcc cccatatttt
    51121 gtatatcatc attttcatct tttactgtta atctatacct aagttcattg aatccattta
    51181 aaccacattt tctaattgct cttgaaacgg ttgctggaga tgaatatgtt tcatgagcaa
    51241 tctctactat agataattct ggtaatattg attcattttc atttataaat ttaattattt
    51301 caagttccgt cttcgttaga ttttcagaat tacttttgtt tatctcaatt atcatatgct
    51361 atctcccctt atataagttt tatttgtcta aatttatcga gtaatataat atattacctc
    51421 ttaactactt atttttatat acaattaaga tttagtcaat gtctatatat gtaaatttat
    51481 aatataataa ttttttgctt aaagtttatt atgttatctt atagcatttt aaaataaaaa
    51541 agaattgtac ctctaccaaa atttggatga agtacaatag atattcctca tactgatatg
    51601 tttatgatta aaagtataaa tataaatttc gctatgaatc atataattaa taaatcattt
    51661 tatttacaat tataaccccc cttataaaac tatattaata atatatacag tatttataag
    51721 gggggttgtt tatatttaaa aactatttac ttttctttta attcttctcc attagttctt
    51781 attaaatttt gataccaata aaaactatct tttttataac gttttttact tccatttcca
    51841 ttgttatcta tatccacata tataaatcca tatctttttt ccatttcttg agatgaacaa
    51901 cttactatat ctattggtga ccacatacaa taagctaata tttcggttcc atcagctata
    51961 gcttcaccta tttgttctat atgttttcct aaataatcta ttctgtaact atcatgaact
    52021 tttccatctt caaatttatc atgcattcca aatccatttt cagctatcat tattggcttt
    52081 tgatatctat cataatattg agataaagta ttgtataatc cttttgggtc aattgcccac
    52141 ccccaaggat ttgcttttaa atatggattc tttatattgt cagttggatt catggtgttt
    52201 ttacttgctg atactgttgt agaataatag tatgataaag ctagaaaatc catagtattt
    52261 tcttttaaga ttttatcatc accttcctcc ataactatat ttatgttatt ttctttgaaa
    52321 aatctcttaa tatagactgg atactctccc ctaaaactta catcagtgaa aaaatattgt
    52381 agcctatttc tttttaaagc aaatactaca ttttcagggt cacaatcttc tggataagat
    52441 gtacaatctg ccatcatcat ccctatcatc atatctgaat ttatttcttt tccaagcttc
    52501 ttagtcaaag ctgtagctat gaattgatga tgaatagctt gatatctagc ctcttctaca
    52561 ttatctactt ggtctacaca aaatgcaact gaattaaatg attcataatg tattaaattt
    52621 atttgattta taactatcca atatttaact ttatttttat atctatttag tattaattct
    52681 gcatatctaa caaagaaatc taccactttt ctattagacc atcctttata ttttaatact
    52741 aaattcaaag gagtctcata gtgaagtagt gttacaatag gttccatacc attatctatt
    52801 acttcattta taagattatc ataaaacttt aatccctctt cattaggctc taaatcatct
    52861 ccatttggaa atattctagc ccaatttatt gaaaatctaa aacactttaa ccctagctct
    52921 ttcaaaagct ttaaatcttc tttgtatgta tgataaaagt ctattccact acgcttagga
    52981 tagtacccat ttttatcttt catagcaaac tttattcttt ctatagtcat atcagactca
    53041 taaggtttag atatatctct atctttatca tacatatgta catcagctaa acaccaacct
    53101 ttgccacctt cattccatgc accttctaat tgattagctg ctacagctcc tccccataaa
    53161 aaacctttag gaaacttacc caatttaatc actccttatt ttatttattt aaatcattta
    53221 ctattattta ccttatattc tatagacttt actataccta ctaaagacat agttatattt
    53281 aactcgctga atatggtcat aagagtatct tgagcatgtg caaataacag cgaatgtgct
    53341 cttttctctc caccagcttc cccttgtata atcttggttt gagctctatg tgcttctgtc
    53401 ataaaccctt ttgctttagc tagttttaaa tcggcatttc tataatcaaa cttttccaaa
    53461 tcattaagag catgtttaat ttctgttcta gcctcacctg cacgaagtat tatttgcatt
    53521 gctacttcta ctaattcttc atctattata tgttcttcaa ttgtcatatt tataatttcc
    53581 tttcaatttc taaatttaaa cctcttggct ctctaatttt atctcttctt tctcataagc
    53641 tttaaaaaat ggataccata tcataaatag caatactata tttattgcta aaacaataag
    53701 ccctctaaca tcttgattta ccataaaagt agatatacca aaaggaacat accataaatt
    53761 aaacacctta cttggaattg tcacaaatcc catactcatt gataagtaag tagttattga
    53821 tattactact gttcctatcc acataggtaa cattaaaaat gggttccatg ccactggagc
    53881 tccaaatatt actggttcat ttatattcat tatagaaggg acaatacatg ctcttcctat
    53941 tgcttttatt cttccaactc tggataaaca catcattata actaatggta atgtagcacc
    54001 caaccctcct aaagttatcc aacctgtttg aataacttcg taaacatata tattagttgc
    54061 tactcctcct gatgctactg ctgctgcatt agctgcaatt gcaccaagtt gaattgaata
    54121 agttatagga gatagtaccc acccacttat tcctaaagaa tatataaata ctactaagaa
    54181 gtttaagagt acaaatccag gtaatgtctg tgctatatct gatactggtt taaatactct
    54241 aactattatt tcaaacatgt caaagttgag tccataaatt aatccccagc ctacaaacat
    54301 tatcactgtt ataggtaaca tattatcaaa ccacttgctt acaaaatctg gaagtgctga
    54361 atcttctccg aaaaatgaaa aagaaccaaa taaagacatt attaatccag agaataatcc
    54421 tgcaactagc gatacaagca ttccttctcc tccaaacctg ttgaagttaa atatagctcc
    54481 ttcattcgta atctctggac gaatcatcat taacattaat ccagcgcctg caagaccagc
    54541 tactacactc atactttcaa atttcttatt cttcattatt tccataggca ataaaaatgc
    54601 tataaataat cctaaaagtc caaatgtata ttgatttatt ggacttaaat caggtaaaaa
    54661 gcttatgtaa ttcttcaaga cagaaactat agttactaat gagcctacaa ataccattgg
    54721 caaaactttc attatagttg attgaactga ttgtacccat atattcttag tcatattatt
    54781 tacaacagga gtaaattttt cacttaaaaa atctataaat ttattcataa acactctccc
    54841 cataaatatt ttatttgttt gatattagtt ctagtgcttc ttccaaagcc tttgcaccat
    54901 ctagtcttcc atatgcagtt ttagatatac atgctactgg aacgttatat tcattagcct
    54961 tttgttgaat ttcttccttc atataatcta aatgtggtcc tagtaataaa caatctattt
    55021 ctgataaata cttatctatc tctgactcac ttctcgcttt tatatctgct tctatacctt
    55081 ttttctttgc actctttctc atactagttg ccataaaacc tgtacttgct cctgaaccac
    55141 acgccaaaag cactcttata tttttcataa taatacctcc aatattttta tccattaatt
    55201 tatttcttaa tgaacttttt attttattat gtttatattg tacttaccaa ataagttcat
    55261 ttcacataaa tatatttcct aataatagga aatcagttac tcttaattaa acatattaat
    55321 atagtataat gtatcttata atacgtacat tcaattatat aattatcata tcatccagat
    55381 tttattttaa aactatgcga gggaatctaa tgaaaacatc taaaaaagaa ctatttttaa
    55441 atttcataaa aacacaacat gattggatag attcatctac attggctaat tatcttaatg
    55501 tctcaacgcg ttcaattaga aaatatgtaa acgaaattaa ttccaatggt gaatttatat
    55561 tatcctctaa aaaaggatat aaagtaaatc tcaataataa ttttcaaacc aaggttgata
    55621 gttcagaaaa tatatcacct gataacaggt taaatttaat tttaaaagaa cttatagtta
    55681 atagtaatgg aattaatata tttgatttaa gtgaagaatt gtttgttagc ccagctacta
    55741 ttgaagggga tatagtcaaa gctaataaat ttataggaag ttataattta aagataaagc
    55801 aatcgaaatt tttattgaaa ctaattggaa atgaatctgc aaagcgcaag ttaatgagct
    55861 ctataatatt taaagaaacg ggaagtgatt ttttaagctt atttgatgta caaaaaatat
    55921 atcaagagta taatttgact aaactaaaag aaaatataat atatatatta aaaaaataca
    55981 atttatttat aaatgagtat gctataaaca acatacttct tcatttaatg ataactatag
    56041 acagaataaa aaagaataat tacatagact ctgttgaagt agtaaactac atagacaata
    56101 acgtagatat aaatattgca aaagacatat caaatttttt agaatctgaa tacaatataa
    56161 ctttaactag tgcggaatta tactatttag tatttcagtt aacaaacaaa actacagtct
    56221 taaactacaa tcaaatggat actaaatcat tgtcaaatta tatagatgaa cactttgtta
    56281 aattaactaa aaaaataatt aaaaatgtat atgacttata tcttatagat ttatctgatg
    56341 aggaatttgt tgtaaaattt actcttcatg taaaaaattt aatcagtaga gccaaaaata
    56401 atcaagtttt aagaaatcaa atacctcaaa agttaaaaga ttcctaccct ttgatatatg
    56461 atatatctgt ttatatttgc aatcagattc aaactttaga aaatgtagat atagacgaag
    56521 atgaaatatc ttatatatct cttcatgtag gttcattctt tgatagacaa aaattattag
    56581 aagataaagt tctatgtgca ttaattactc caaattacta tgatttacaa ttcaaaatag
    56641 taagagacct tgagaagaga tttaatgaat ccatagaaat tattcagatt ttttcagata
    56701 ctcataatct tgattttgac aataaggtag acatggttat tactacttta ccaattaacg
    56761 atagatgccc tatacctttt gtttatgtaa atccttacct aaatagaaag gattatgata
    56821 atattcaaag taaatttatt cagattaaag atagaaaaaa tatacttact gtacaaaatc
    56881 atttagaaat gtactttagt gaatctttgt ttatgaaaaa tatatattta gatagtgcta
    56941 aagattatat aaaatttatg ggaaatattc tgtacgaaaa taaatatgtc aaacccaatt
    57001 atatagatga tgttcttata agagaaaaaa tgtcttcaac tgcatttaat aacaatgtag
    57061 caattcctca tagcatgaaa atggatgctt taaaaactgg agtatgttta attgttaacg
    57121 ataaaccagt taaatggggt gaggaaaaag ttcaaattat agctatgata cctataaatg
    57181 aaaaagaaaa agaaaagttc aattacatat ttgaaagctt tattgaaata ttatctgagt
    57241 ggaataatgt taaagaactt actaaggcag ataactatag tagttttatg aatagaatag
    57301 cttatcttat tcaaaatatc taaatccgtt aatttatttc caatatatgt ttcttaagtt
    57361 attaacataa aatagataag ctgtcacact aaaaagtcta aattaatatg tgacagcttt
    57421 ttacctaata taccttgttt taatactaca tattttttga ctgttgtata ctagttataa
    57481 gattgaatat ttgtgttgtt gtagctgtca tattctcact agcagttgct ttatccattg
    57541 cttcttctat tgtcatagct ctatttacta tagaaaaata agcatctata ccctcttcat
    57601 tacatttaac tgcatcttct gttgtggctc cagccaaacc tattactttt accccatatt
    57661 tttttgccag ttttgcaact cctattggag ccttgcccat agcagtttga ttgtccaatc
    57721 taccttcacc agttatgaca aaatctgcat cttttaactc ttcctctaat ttaatttctt
    57781 ctaatattat ttttattcca gattctaatt ttgaatttaa aaatgctaaa aaagcaaaac
    57841 ctaatcctcc tgctgctcct gctccttcta cattagctac atctttactt aagtaatttt
    57901 taactacttt ggaaaaattt ctaagcccat tatctaactc ctcaattatt tctgatgttg
    57961 cacctttttg agacccgtat atgtatgcag ctccattttt cccaaacagc ggattattta
    58021 catcacaggc tattttaaac ttacattcat ctaattcctt taatctattt tctattttta
    58081 tatgtcttat ttcatttaaa acttttccac ctaatcctac taacttgtta tttttatcat
    58141 aaaactcaaa ccctaaggct tgaagcatac ctatcccagc atcattagta gcacttccac
    58201 ctatcccaac tataaaattt ctatagcctt tatttattgc ttcctttatt atttccccaa
    58261 caccataagt tgtagtgtat aaaggatttc taagttcagt cggaaccaat gttaatcctg
    58321 atgcttgagc tatttctatt attgctgtac ttgtattttt taataatcca tatgttgcat
    58381 ccactttttt agctattggt ccagtaactt ctatagtctc ttttttacca ttcatccctt
    58441 gaactaaagc atctactgtc ccttcaccac catcagcaag tggcaatatc tttacttgcg
    58501 catcttcttt aaccttcaat atcccctttt ttattgcatt tcctgcctct attgaagata
    58561 agcttccttt caaagaatct atagaaatta atattttcat atttatctac tcctttttat
    58621 tactccttat tttaaacata taattttata agcttaattt atcttttatt ttatactcta
    58681 catctctctt tgtatacaac ttataccatt aatattcttt tatcttataa aaagggagtg
    58741 tctcaaaata aatttcttag ttcatgagac actctttttg tataaaatca aatatatgtt
    58801 tattatttca acaatgataa ggaggattat ctctatttta agataattcc tttttagcac
    58861 tatctaatca tttttagcac tatttaacca atatagtttt aacttggttc attaagcact
    58921 ctacatttac agagttatta tctattgata tagattctaa ttctttttca tttaggttaa
    58981 tccatttagc tattttaata tttttgttaa atactatgtt agctgatttt gtttcttctt
    59041 tagaattata aaatctaact actaatgcct cttgtttttc agcctttttt acaacactta
    59101 acacaaggtc cttattagtt tccttaagta aactatatga ataatctact tctatttctg
    59161 attgattcaa tttcatagca ttatatggca ttttattata agtttgtatt tttgttaaat
    59221 actctttagc catatttgca acatttgctt ctagtgtaga tttttcatga gtaactattg
    59281 ctaagtctat ttttatatct cctatcattt gagaatctgg agtaggcaac tttattcctg
    59341 atggacgacc tgggcgtctt gccatttctt ctttacctag gaatcctaca cttctaaata
    59401 atgttatagc tattgtgtca aatttttccc ctactatttc aaactctctt gtactgtttg
    59461 taagaacagc tactccatgc tctttgtcag acaatccaac gaatgttagc attggatata
    59521 tagaatctgg tctttcactc cattcttctt gttgccaaac ttccatagca tcatcataca
    59581 cacttctctt tatatgtcca aactgattat cagacacaga aaactttgaa gctatatttg
    59641 ttggtatata agttctaacc ctacaatctc ttgcttggtt atttatgttg aatactacat
    59701 ctattatagc tttatcattt ggaacattta taactatatc aaagtcaata aatgaatctg
    59761 ccctattatt ttttctagct tgtatatctt ttggtacttt taatctataa tttatcttta
    59821 tctcattatt aaatctattt ttctttatag tggaatttgc tactatatta tcgttaaata
    59881 ttaatttctc atttggaagt ggtgaaaaat catactcatc tccttcatct cctccatttt
    59941 ccatcaataa tacattttca aaagttttat ttaatttttt atcaaatatc tttaatgtcc
    60001 cgttttcatt aatttgaata gtataaaagt cattatctac catgtcacat acttcataag
    60061 ctttttctaa catatgtcca atttctttta tcatatacgc cttatacccc attgcaggta
    60121 ttttatcttt aaagtttatt gtatatacca taaatgaatc atagtttcca taatgaacaa
    60181 tttgacggtc tattaatcct gcatctatta cttctttatg taccacttca aaatccaact
    60241 tattattatc tttatcaaat atttcaaatg ctttcatttt agttataact tgggcgttca
    60301 ctatttcatt cctatcgtaa ggcattaagt taaatgctac taacttatct aaagccattt
    60361 cacaactcat tgcatcaact attcttcttt tgtaaaatgt tattaattgg tctacttttt
    60421 cctcagctaa gaaaaatcta ttcattattt catggtgaac tttatctgaa caacaacatc
    60481 caatgctgtc atgagcatga tttttcatta tttctttcca aattaactct attaatccat
    60541 gatgatattc aaatcctaga gaatatgcaa tagaagctag tggctccaat atgttggtta
    60601 tctttgattc tattctagca tttgctgatt ttatatccat tcttgttgag aatatacttc
    60661 tatgaaccct catatatttc ccatctaaaa attccccttt tattgtatct atatcctcat
    60721 ttttttctag ctctttaaat atgttttcat atctacttaa gaaaaatttt ctctctggat
    60781 aacattcttt taatttatat ataacttcaa atatattctt ttgaattggc atctggtcat
    60841 gtccatttgg aagtattata tggtcagtag ttgcaccctt atcaagaacc ggtaaatatt
    60901 tatccattct tgttcttagc tcatcttcat tcattggtag atattttcct attgcataac
    60961 ctaatggaag tatttgaacc aaaacagaag acccatcatc actcttccaa ttaaactctg
    61021 ttttattagt tccttttctt tcagaacatc ctctccaaaa cattgagtat tttatatcaa
    61081 acccatttag tatttgtggc atttgagcac tttgaccaaa tgaatctggt aaatatccta
    61141 ttttcatata ttctccaaat tcatcacaat cttttattcc atatagtaaa tttctaagta
    61201 tggattctcc accaactacc atttcatcag tttgagtata ccaaggacct attattaacc
    61261 ttccttcttg aactaatttt tttattctct ccttacattc aggcttaact gctaaataat
    61321 cttctaatat agcagtttga ccatccatca cataatatgg atagttatga ttattttcta
    61381 acatatccat tatttcttcc atattattta caagtaatat tctagattcc tcagttgaga
    61441 agtaccattc tctatcccaa tgcatatgag gaactatgtg tacatttttt ttcattgctt
    61501 atcctccaaa acttatctga taatattttc tgtctaatta aaaatccaat aaaaatacta
    61561 ctgagtttac aaaatttttt aatatttatt ttatcactat aattaaacct ttgatttaaa
    61621 tatctaataa cgtatctttt tatgtatctt tctttgattt ttttgtttcc tagttattat
    61681 taataatatt gctgatatta tagctccaag tactgccgca aagaaccata ttgatgctat
    61741 aataaatcct gacatacttc cctctaaaag cgccaatgag aatatccccg ctccaggcac
    61801 ttgaagacct atattgaaga atgctactat agacccagtt atggctgaac cagctaccaa
    61861 tgatggtata acacggattg ggtcctctat cataaatggt attgcacctt cagttattcc
    61921 agccaatcct aatatccaag tttgctttcc tatttccttt tctgattctg aaaataaatc
    61981 tctgcctaaa acagtagcta ttgtaactcc aaaagctgaa accatcttaa ctgatgcaaa
    62041 tattgcataa ggtataaaat ttccacttgc tattgctcct attgcaaatg tataggctgc
    62101 tttatttatt ggtccaccta agtcaaatga aaccatagct cctattattg cacctagtag
    62161 tattgcattt actccagtca tcccatttaa ccaatttata agaccattgt taagtgctgc
    62221 tacaggcttt cctactacaa ataacatcaa taaacctact accaaagaac caactactgg
    62281 atatacccaa aaacttacga atccagctaa tgtgcctttg gctggtatat tcttctttaa
    62341 aaattttact atataaccag caagtaaacc tcctaacata cctccaagaa atccactacc
    62401 tattaaatca gctgctagac ctgctgcaaa tcctggtcca agacctggtt tttcagctag
    62461 tgagtaagac atatatgctg ataatactgg aaccatcaat gtacctaaca tacctccaga
    62521 aagctttctt aattgccata accaagaacc ttcttggttg tatagttctt gtagaccaaa
    62581 tgcttgagat gctaatactg caaatgcaag tatcatacct cctgccacaa taagtggtat
    62641 tatatgagat actcctgtaa gtattgctga ttttacatct tttttccatg atgatttttc
    62701 acaatatgat atatcagatg atttttctat ataatcacct ttaccttgtt tttgtgctac
    62761 ttctaaagct tcgtatatta tttcttttgc tctttttagt ggagctgcta ctgacgtttt
    62821 tatgtttggc aaatgttcaa atctttctgt atttttaggt gctacatctg ttgcatatat
    62881 tattgcatct gcccttttta ttatatctgg tgtatgaggg tccaccatac cattagctcc
    62941 ttgcttttct acatacacat ccacaccgat ttctttacca gctttaatta atgcttctgc
    63001 tgacatatat gtatgtgcta tacctgcagg gcatgctgtt attgctaata caattttttt
    63061 tgattcattt tgaatcctaa tctcttcttt tatttgttct ttcttttctt ttatatctaa
    63121 gttattaaat aactctttct tagtttttga atttaacaac atattcatat aatcttcatt
    63181 tgacagtcta gtaactaact cagaaagtat ttgtatgtgt gtatttccac ctttattttc
    63241 tggtactgct attaaaaata ttagctctac tttattattt gggtctacgc tttcccaatt
    63301 ttctattggt gtctctaagg tcatagctgc aaatgaagct tctttaactg acttagattt
    63361 tccatgagga attgcaagcc ctctttcaaa acctgttgga gataaagttt ctctgtacat
    63421 tacagcttct aaatattcct cataagatgt taacttgcct tcatcatata gctttcttgc
    63481 taagaacttt attgcgtctt tctttgtttt tattttttgt tttaaaaaaa caaggttttc
    63541 atttgtgatt ttcttaaatt ccaaaattac gccctcctta aatcatttaa tgctatgaat
    63601 atagcataaa ataaattatg aaaatgtttt tttgaaatta tacacacaat ttcttcttaa
    63661 aaaataaaga tttgtgtatt tatacacaaa tctctatctt aaccagtatt gctctattat
    63721 tgctctcata atcatcataa ttggaacctt atctgatata ttgtacccat ttacttgttt
    63781 aattgttgaa tagcaatata aacttatatc tgcaatttgt tgcaattgat tttcacatat
    63841 atgtgttaga gctactacct tacaaccctt attaactgct gtctttgctg cttctataac
    63901 ttctttcgtt tctccactta aactaagtgc aaaaaacata tcttgttcac ctaattttcc
    63961 tatatcatga agtacttcat gtctttgact atagtaagtt atattatcat gcccacctct
    64021 aatttctttt actaatatct cacataaagg aatgttttga cctattccat aaactataat
    64081 actcctagat ttttgaatta tatctgctac tttatttatt ttttcataat ctattagctc
    64141 taatgtcttt tttatatctg attcaaaacc attttttggc tctttatcct cattttttaa
    64201 ctcttctttt aaattatttt ttagttgaga gaaaccatca tactccattt ttttacatag
    64261 cctaactatg gtatttggga cagtaaaaaa tttatctgct aaagattgta ttgataattt
    64321 tactatttct tctttgtttt ttctcatata ttcaattatc atgtcttctg tatctgtaaa
    64381 tttatactca tatttttttg ctctttcata aaattccata gtttctcctc catctatttt
    64441 attattcata agtaaaattc aaaaatatta gctaaaattt tcgttaatat aattataatt
    64501 taatattttt aatttattaa tgcatactac tctttttatt atacataaaa aatgtgtact
    64561 tcctatattg atagagatta ttcaagtttt tattttgata catctctatc aatatttttt
    64621 tagaaaatac acattttttt caaatactta tttttaatta aaactttagg taatctattc
    64681 tttatatata attattagac ttgaaaatat ctttaaaatc aaccaattca atattatttc
    64741 tttttaacca cattttaact tccttatcac atagcattgc atgttcatat actctttctt
    64801 gaataagaga agatgatttt ataagactat aatctataaa tcctggatga gtaaccatca
    64861 atgttatatc tttatctaaa tttatatatt tttcttcaaa taatttaaca aaagatttat
    64921 ttaacttgta aaaatcattc tgaggatatt tacttggcat gctaatacat gaatctaaat
    64981 aatagggaca acttggtata ccgtattctt ttgcagcatc acacattgct gatattgata
    65041 catcttcttc tataccatgt atatcaatat actcaggcaa tttactcata tacaacttgt
    65101 aagtttcaat ttgagcacaa acttcttcat atacttcttc ataattaaaa acctctttac
    65161 ctgtcagtag ttgcgttctt cttattttgc tagaaacaaa ttttccacct tcatctaaca
    65221 aattctttat cttaatatgt tctttgcaac aaggttctcc tattactaaa ttaacatgta
    65281 aaccaaaaca tacatcatca ttttttacca tttctatagc ttgtcttgaa aaaggcatat
    65341 tcaccatgat tccagcactt gtaacaatac cgttcttata agaagatatt atccctagtg
    65401 taacaccttc tgaatatcct atatcatctg ccctaactac tagtttcttc attttatgcg
    65461 tctgcctgct ttctcaactc atcaagttgc atttccatct catcctttac tttaacaaca
    65521 tccgttccta tgatgatttg aactgatgta ttactcaatt taattacccc tttggctcct
    65581 gtttttttaa tattatcatc attcaaaata gtagcatcct tcacttctaa acgtaatctc
    65641 gtcatacaat tattaagagt cactatattt tcataaccac cacaattttt aattatctgt
    65701 ttagccatat atgaaaaatt accatgagaa agttttaaat tcttttcttt ttcactaact
    65761 ttatcaccta tctctatctc aacttcacgt cctggtgttt gcacattatc ttttattatt
    65821 atatatttaa atgttacata atataataca aagaacacaa ctcctacagg tataactaac
    65881 cacgctttat ctccataact aaaacttaag acatagtcaa ttatacttgc tccattaaat
    65941 gaacccaagc gagcacccag taaatatagt acaactccac ctagaccaga ataaaaagaa
    66001 tgaattatat ataactttgg agatgcaaat aaaaacgaaa attctattgg ttcagttact
    66061 gttgccataa aagaagtcaa tgctccagcg gtcattgcac cttttacttc ttgcttcttt
    66121 ttatcttgtg ctgttttata tatagcataa gaaatagcag gtattgaaaa catcataatt
    66181 atgtaaaatc ctgtccagaa gaatcctgca tttgggtctc ctgccataaa tctaggaatt
    66241 tctcctctta taacttctcc tgttgatgtt gtatattcac ccatttcaaa taatatgtaa
    66301 gcatttaaaa cttgatgtaa cccagttggt attagtgcac ggttacagaa taaaaacaag
    66361 aatattccta ttgcaccagc tcctcccaac caaaaaccaa attgattcat tgcagcttgt
    66421 ggatatatcc ataataaact aaatatatat gataaaatta aagcaaccac tggtgatagt
    66481 gtaattacac atttttctcc tgcaaagaag cttaaaaatg ctggaacttt aactttatat
    66541 gttttattgt aagtccatgc tatacaagct ccaacaatta tcccaccaaa tacacctgca
    66601 tttaatgtat cattcaataa ctctaaattt gacttaaata tcatatatgc aactacggct
    66661 gcaaccatta cacttgtctt gtctttagac tttgagtagg cactagctgc tcctaataaa
    66721 aataagtagt ccacatttga aaatactata ttagatatat tagatatagc tggcacattg
    66781 agcatatttg gaccaaataa taatcctaat atacctgctg ctggcattac agctattggc
    66841 accagcatag tctttcctaa aagtgacagt tgttgcatca ttttgtttaa gaacctcttc
    66901 atatacaatc ccctttctat ttcggtttaa ttttttgtga aaacgattta ttcacatttt
    66961 atattttaaa tattatattt gtttaaacaa attgtcaata ttttttattc attttatttt
    67021 tatcatttag tttaacatat aaatcctttt aagtgtattg ctatatctag cctatttttt
    67081 taattcattt tttttatttt aaaaatatgt ttaaccatat atttgaaaca acccacaaaa
    67141 taattctatt ttgtcctttt tatggttgat atgattctat tttcactata catgtctaaa
    67201 cacatttgat ataatttgtt catatcagtt caataatatt actaaagacc tttaaggagg
    67261 gataggggta tatggctaaa aataaatttt cagagatata tgaagtattg aaagaggaaa
    67321 tacttgatgg taaatataca agtaatatga tgctgcctac tgaacttcaa cttattgaaa
    67381 ggttttcatg tagcagaaac actgtacgta gagcaatttc tcaattaaac acagaaggat
    67441 atgttcaaag tataaaaggc aagggtgttg tagtgttaga aaatagttgt tctaatgatt
    67501 tttttctaaa tatgcacaat ttcaaaggtg tagaatcgat tgtagaagat aaaaaggtta
    67561 atactgctac tagtgttctc cacttcagca aaatcttaat tgataataag ttatctaaaa
    67621 agacaggttt taaagttggt agtgaagtat attaccttca cagactaaga tatattgata
    67681 acatacctaa aattctcgac attaactatt ttctatgtag tatagttaaa gaccttgatg
    67741 tttctatagc acaaggctct atttataaat atatagaaga gtgtctaggt acaaaaattg
    67801 tttcatccag aaagatattt aaaattgaaa aagctacaga gcttgagtta aaaacgctac
    67861 ctctaaatga ttataattgt gttggtgtta ttaaaaatag tgtatatact gatgatggaa
    67921 agctttttga atatactgaa tcaaagcata cacctgaaac atttgtattc atggatgtta
    67981 ctcaaagata ttaaaaaaat tatgtttaat taaacataat ttttttacgt ttagacactt
    68041 tatcccatac taacctcact attctatata caattatatg tttatacaaa taattattta
    68101 ttgtatattt tagctttaat attagtttaa cgcttgacaa tttgtttaaa catattataa
    68161 ttaacttata aattacagga ggtatcaatt atgaaaaatt ggtggaaaaa agcaactgtc
    68221 tatcaaatat atccaaaaag tttcaaagat agcaacaatg atggtatagg tgatataaat
    68281 ggtattatag aaaaattaga ttatctgtat tctttaggtg ttgatttatt atggttgact
    68341 cctatgtacg tttctcctca aagagataat ggatatgata tagaagatta ttataatata
    68401 gacccaaaat atgggacaat gaatgacttt gaaaaactct taaaagaagc tcataaaaga
    68461 gacataaaaa taatgatgga tatggtccta aaccatacat ctactgaaca taaatggttt
    68521 aaagaatcta aaaaaagcaa agacaatcca tatcgtgatt attatttctg gaaagatgct
    68581 aaacctgatg gttctgttcc taataactgg atatccagat ttagtggaac tgcttggaaa
    68641 tatgatgaaa ccactaacca atattattta catttatttg aagaaactca agctgattta
    68701 aattgggaaa atgaaaaggt tcgtgaagaa tgttacaaaa tactagaatt ttgggctgat
    68761 aaaggtattg atggttttcg tttagatgta gtcaacctac tctccaaaac acctggatta
    68821 cctgatgacc ctataacagg accaaaagga gatggaagaa ctcactacgc tgatggtcct
    68881 cgtatacacg aatatttaca taatatgaat caaaaagttt tcaaacctaa aaatatagtt
    68941 actgtaggtg aaatgtcatc tactacacct gaagagtgta tcaactatac tagagaaaat
    69001 cgagaagaac tatctatggt ttttagcttc catcatatga aaacagatta taaaggaggc
    69061 gcaaaatgga ctaatgaaat gttctctctg gataaattaa aaaaagcaca atctgacttt
    69121 caatataaaa tgtatgaagg aaagggatgg aatgctctat tttactctaa tcacgaccaa
    69181 cctagagctt tatctcgatt tggagatgat agattttttc gtcaagaaag tgctaagatg
    69241 ttagccataa cattatttgg tctacagggt actacataca tatatcaagg tgaagaaata
    69301 ggtatgacaa atgcctactt tactaaaata gatgaatatg atgatgctga aagtaagaat
    69361 gcatactatc atatgattaa atctggtatt gatgaaaagg aggcattgct tatacttcaa
    69421 caaaaatcca gagataatgc ccgtactcct atgcaatggg ataatactat ttataagggg
    69481 ttttctaatc ataaaccgtg gttaaaagtt aataatgaca atattagtgt agaaaatgag
    69541 cttaatgatt ctcgttcagt attttatact tatcaaagat taatcaaata tcgtaaacaa
    69601 tatgatattt ttacagaagg tacttataga ttgttagatg aaaatcataa aaatctattt
    69661 gtttatgaaa gagagtataa aaaccaaaat cttcttgtta taagtaattt tactcatgat
    69721 aatgtagtat ataaattacc tgaaacttat ttgaataaat taaactacac aatacttgaa
    69781 accaattaca ctagagatat aattgaaaat aaaatggaaa taaaacctta cgaaagtata
    69841 atgatatatt ataaataaag ttatttatgt aaaaatcggt ataacaccct ggtgttatac
    69901 caattttact aaattcaaag taatatttat agaatatcta tagattagaa taattatttg
    69961 acgtctacat cattatattt ctttgaatat actttagtca tatagaaata tataggaact
    70021 acaattatca tcccacctaa tccccaaact atcttcatag gttcatcaat acctgctttt
    70081 atcagtaata atatacttat aataactgca aatattggta taattgctcc tccaggtatt
    70141 ctaaaattta catctttatc agcatacttc tttctcaata ttagtacagc taaacatgta
    70201 ggaatatatt gaataaatct agatacaaca cttatttgag ataatgttgt gaatgaaccc
    70261 gaccatgcta ttagtaaagt tcctatgaca gatactataa ttgctatata aggagctcca
    70321 tttttattag tttttcttat agacttaggc attaatcctt gttcaaccaa agcagcagca
    70381 gaccttggtg taaatatgga tgatgcaata tttatacctc caacagatac tatagttcct
    70441 attgtaatta tatacccacc tataggacct aacatcttaa tggcagcatc tgcaacagga
    70501 gtagctgacc ctgccaagcc attacccaac actcctatac ttattcccag tataagcata
    70561 tatattactg atactacaaa cattaccatt accaatgctt taggtacatt tttcttaggg
    70621 ttctccatat cttttgctgc aacagctaaa gattcaaatc ctgtaaaagc ataaaataaa
    70681 gttatagata ctgctacaaa agctgatgac gcactttgac ctttttgtat tattacaaat
    70741 ggggtaaaat tagaaccctt tataaagaat aatcctacag ctataaataa aactattggt
    70801 aataattttc ctatagtcat gatattattt aagtgcttag attgtttcat tcccataaaa
    70861 tttataatcc caagtcctac aactaatata ccaattatta tatttttagt aagtggttct
    70921 gctgcttgtg gccatacaga tgatagtgtt acagcaaaga aatttgccat agtagcccaa
    70981 gcaatcatac taactatcca cttcataaat ccaacttcaa atccaacaaa atctccaaat
    71041 gcctcttttg cataaagata gggccctcca tcagtatcaa accaactacc tgcttcagca
    71101 aaacataaag caatagaaac agctaaaagc atacaaaaaa ctaatactaa tatacttgct
    71161 ggacctatat ctgtataagc atcaccaggt aacccgaata tacctgaccc tattattgca
    71221 ttgattccta atagtacaat actccaaaaa cctaacttaa tgcctttttc cattgttatt
    71281 ccccccaaag ccaacttaat atatttatat tttttattta gatgcttctt taactattgc
    71341 cataaatatt tttttcatat tatcataatc tctagtcatc atttctggat gccattgtat
    71401 ccctattaca aactcacttc cttccttttc tatagcttca attaaaccgt ctttagatgt
    71461 agctgaaaca atatatcccg gtgctacttt gttgacaact aagtgatgaa aactattaac
    71521 taaaacttct ttttctccta atatttcata taattttgtc ccctccttta tctgtactgt
    71581 atgtgtaggt acattagata gatgttgctg attgtgttta atataagcac cttcaattaa
    71641 agataaatct tgatacaaac tacctccttc aattacattt ataatttgtt ctcctctaca
    71701 tatccctaaa actggttttt tcatatctaa agcatgtttt aataatttca tatcaaaact
    71761 atctctcttt ggtgatattg cccccaactt attatgaggt tcttctttcc atatgagtgg
    71821 atttacatct tgtcccccag atagtataag cgcatctata ttagatacct gctcctttat
    71881 aatctcatca tcatatacaa tcggtacaat atatggtata gctttacaca taactactga
    71941 ttgtatataa tcattattta cataagccct ttcatagcca ggaaacattc ctccttcatc
    72001 aattagtaaa ttacctgata ttcctattat tggatatttc tttttagcca atttcttcac
    72061 cccttaactt atttgtgaac aataaaaaat gctacttctc ttaaagagca agtagcatac
    72121 caagatttta tttatttgaa cattataatt tattttagaa atactttttt tgaatacgag
    72181 taatataaat aactttattt acttatattt tattttaatc ctgtttagtt tgactttttt
    72241 aaattgtttt aagtacaact aataggtaaa ataggcattt agattttcct ttttatcaac
    72301 ctattaaata ctgtttaata tattttttcc ccttctattt aattcacttc cctttctacc
    72361 agattcacat attatcaaat ccagctcttt taacatatta agtattcccc ttacctcacc
    72421 ttctgttata ttgtagccta atccatttat tgaattaaca ataccatttc tacctatatt
    72481 tttattaaga ttattagcat tttttaaaca ctccattact aactttactt tctctataga
    72541 tgttctatcc tttaatatgc ttatttcttt actaaaatct tcagttatat ttaataagtt
    72601 atgaggtaaa tcatttatta aaataacatc ctcagaactc ataatgttaa tatacatagc
    72661 agtatttttt aattctctta tattacctgg ccattcatat gcattaataa tgtcttgaac
    72721 atcttgacta attgctctct tccttttcat aaaatgcctt aacataactt ctatatcttc
    72781 ttttcgctct cttaaaggtg gtatatttat gggcaataca tttatcctat agtataaatc
    72841 tgctctaaat ctatctcctt ttatcatttc taataaattt ttatttgtag ccgcaattac
    72901 tctaacatct atatctatta cattttctcc tccaaccctc attacttgat tctcttgtaa
    72961 tactctaagt aatttgcttt gtaagtatat aggcatgtct cctatttcat ccaaaaatat
    73021 agttccattg ttagcctgtt caaataatcc ttttttacct ccttttaaag ctcctgtaaa
    73081 agcaccttct tcatatccaa aaagttcact ttcaagtaaa ttttctggca tagctgcaca
    73141 gtttattgct ataaatggct gactatgtct tggtgatgca ttatgaatag actgagccat
    73201 gagttctttt cccgttccac tttctcccgt tataagaatt gtataatcag attcagctat
    73261 tttcatacct aatttcttag ttctttccat cttcgttgaa actgttttta tatcatcaaa
    73321 agtatatcta gcaacttgtc ccttttctct aagcttcttt gataggtttt gctccaattt
    73381 tcttatgtaa gttatttctt gaatacaaaa ataataccca gtaacccttc caaaactctc
    73441 tatattatac ttatttacgt ttaagtactt attattaaat tttataactt catcatgtgc
    73501 cttactcaaa ctaaaaatct ttttaatatt ctcattctct aattcatcta tatttttccc
    73561 tataatatta ctttgaatat ctagtatatc ccctaaacta ttattgcaaa taattatgtt
    73621 tcccttatct gataccattg ccatacctaa gtttgataaa tttattatag aatttaattc
    73681 atctgctttt atagtaagtt ctttgtattt agtatttatt cctgaatata aactaattat
    73741 ttcatctgta tacttaatta gcctctcagt aatttcttta tcatccagtt tgagttttgc
    73801 tattatttga ataaacgttg aactatcaat atacctatgg cctaaatcaa taacttcttc
    73861 tatatatttt ggaactaaac ttgcctctcc tggtgttata gctatcttaa catttctata
    73921 ttcttcattg ggattgtatg gtataaaatt caaatggttt attcctatat tgtataaatt
    73981 agatattgtt tccaatacag tatgcttatt atcgtttact actaatacat ctattccttc
    74041 tggcaatgaa aataacttat atatatcctt ttgctttatg ctcctattta tagttattat
    74101 ctttgagaca tcttctacat atttttttat ttttaatact ctatcatcta tcattaccaa
    74161 tattatgtca tcttttatta attccttctc tgttatttta tttaaataat aattttttat
    74221 cattacttta tctttaaata tcatttctag atttttattt aagaaacatt ctaatttaga
    74281 caacccatca gttactactg ctattgtttt catttgatta ctccttttaa aatatactct
    74341 actcttttat aatatacatc taattttcac tttaatagca caaaaaattg tacatttagt
    74401 atactaacat attcctttat tagttttatg tccctaaata tcataattgc aatatctatc
    74461 atatttctta aacttctata aggcaaaaat tgtgccaaat taataatttt cttaatttta
    74521 ttctaaagtt cctcaatagt atttacagac ttagcactta tagcttataa gtctttatat
    74581 tattaatcta tttttatagg ttaattgtac aaatcatata tcacttttac ccattaaatg
    74641 cattataaaa aagatggaat aacgatttgt cactccacct tttttgtaat aaaaaattgt
    74701 atatataaac actatttact actcttctaa gtacaaacag tatctacata ctataacctt
    74761 tcaccattag attctattac ttgtttatac cagtcaaaac tctttttctt aatcctagac
    74821 aagtctccac ttccatcatc atacttatcc acgtatataa acccatatct cttggccatc
    74881 tcaccagtag atgcacttac taaatctata catccccatg gagtatatcc aaataaatca
    74941 acaccatctt ctacagcttc cttcatttgc tctatatgtg cttttaaata ctctatacga
    75001 tagtcatcat ttatcactcc attagattct tttttatcat aagctcctaa accattttca
    75061 actaccatca taggtattct atatctatca taaatttcat ttagtgcata tctaagccct
    75121 tcagggtcta tttgccatcc ccattcacta gacttaagat atggattttt cactccacct
    75181 aatatgttgc cacttgtatt atcttcttta gaatcactac ttacacatgt agacatataa
    75241 taactaaatg tataaaaatc tacacaacct tcttttaaaa tttctaaatc tcctttttcc
    75301 atttttattt caatattatt ttctccaaaa tatctattca tataagttgg atattcgcca
    75361 cgcacttgta catctccaca gaaataattc attactctac tatctctttg agttttaact
    75421 gcatcatctg gattacaagt ataaggatac attgttgcaa atatttgcat acatccaact
    75481 tgataatttg aatctatttc atgagctaac ttaacaacct tagcacttgc tacaaattga
    75541 tgatgtaacc cttgaaaacg aagttgaggt atatctactt ggtttataaa atctgtagtc
    75601 ccttcattta atattccttg tgataagtag cctcccatag gcattgtagc tgaatttatt
    75661 tcattaaatg tcagccaata ttttactttt cctttatatc ttttaaatat tgtttcacag
    75721 taattcatat acaagtctat tacatctctt gaaacccatc cattgtattt ctctgttatt
    75781 gcaaatggta tttcatagtg agatattgtt attaatggtt ctatattata ttttaaacat
    75841 tcatctatca cattttcata aaatttaagt cctgcttcat ttggttcttt ctccattcca
    75901 gttggaaata ttctagtcca tgctattgaa aatctaaata ccttaaatcc catttctgca
    75961 aataaagcta tatcttcttt gtatctgtga taaaaatcta ttgcttcatg acttggataa
    76021 aatgttcctt tttctataac tctcgttatt cttttactta ctttttgaga acctccagta
    76081 cacatatctg aacaagaagg acctttccca tctaaattcc atgctccttc acattgattt
    76141 gctgctgttg ctccacccca taaaaaatct tttttaaatg acatacctat atcctcctat
    76201 tataattctt caccatttga ttctattact tttttatacc aggcaaaact cttcttttta
    76261 ctgcgtttta aagttccatt tccatcatta tctttatcca catatataaa tccatagcgc
    76321 ttcttcattt ctccagtact tgcacttact aagtcaatac atccccatgg tgtgtacccc
    76381 cataaatcaa caccatctaa ctcaacagca tctatcatgg cttttatatg agcacgtaaa
    76441 taatcaattc tataatcatc atttatattt ccattttcat ctggattatc tactgctcct
    76501 agtccatttt caactataaa taatggtttt tgataacggt catataaaga gttcatagtt
    76561 attctaagcc ctaatgggtc tatttgccat ccccactcac ttgcatctag atatggattt
    76621 ttaagacttg caaaaacatt tccttctgtt aaaatattta cttttgggtc tgcacttgta
    76681 agtcttgatg agtaatatga gaacgaaata aaatctactg tgttctcttt aagtatcttt
    76741 ttatcatctt cttccatcac tatatttatt ccttttctct ccaattcttt taatgcatat
    76801 gttggatatt ctccacgaga ttgtacatct ataaaaaagt aattttccct atctttttct
    76861 atagatttcc atacatctag tgggttacaa gtattaggat aagtatttcc tgctgctaac
    76921 atacacccta ttttaaattc ttgatttatg ttatgtgcta gtttagtaac taacgcactc
    76981 gcaactaatt gatgatgtgc agcttggtat tttatttgtt cttcattttc tccctcttca
    77041 atatagagac ctgcacctat aaatggtaaa tgaagtatca tgtttatttc attaaatgtt
    77101 agccaatact ttaccttacc tttaaacctt gtaaaaataa cttcacagta ttttacatat
    77161 aagtctacta gcttacgatt tctccatgct ccatattttt ttaccaaata catgggaaca
    77221 tcaaaatgac agattgttac tactggttct attccatact ttaaacactc atcaaataaa
    77281 tcttcataga attttagtcc ctcttcattt ggaacatcct caactcctgt tggaaatatc
    77341 ctagtccatg ctattgacat acgatagcat ttaaatccca tctcagcaaa taattttata
    77401 tcttctttat aattgtgata catatctatt gcttcatgag ctgggtaata gtgttcatca
    77461 tcacattcaa acattttcat tttcccagcc aaaactggaa atctatcttt tccttgcggt
    77521 gtaacgtcaa cattagctag acctctacca tcttctttat atccaccttc acattgattt
    77581 gctgctgttg ctccacccca taaaaaatct tttctaagtg ccataattct acctccaata
    77641 atttatttat agtaacttta ttttaaaata aaaatacata tatataattc ttaattaata
    77701 gaactctctt ttacgctaaa acagttatca attcctgact attatttaca tgcttttgtg
    77761 tattttctac aatatccaca taatcagaat aattagtaac aactactggt gtttctaagc
    77821 aatatccttc ttttgaaata ctttctatgt caaaagttat taatgtctga ccttttttaa
    77881 tcttatcccc ttgattaaca aaagatttga aatatttacc ttccaactga atagtattta
    77941 accctatatg tatcaatagt tcacaaccat tatcagatat aattcctatt gcatgttttg
    78001 ttggaaataa agtcattaca gtcccatcaa atggtgccac tacttttcct tctttaggtg
    78061 ttattgctac accttttccc aatatacctg ttgaaaacgc tgcatcttgt atctgctcca
    78121 aagcctttac ttcacctttt attgggctat atactacttc tcttttgttt ttttctataa
    78181 cgccttgccc attatcatct ttagaaattt ctactatagc atcatctttc caaaaaaata
    78241 atgttaaaac aaatcctact acaatagcta ctattattgc tattatagtt gcataaacac
    78301 ctttcatatc tccagttgtt ggatttatat aattaggtat accaaatatt ccaagtccac
    78361 ccattacata actttttaca ttcattatcc ccattacagc tcctgccaca gcaccaccta
    78421 cacaactata tatgaatggt gtttttcttg gtaaagttat tccatatatt gcaggctctg
    78481 ttacaccata tatccctgaa ataactgcag gtatacacag ctcttttatc ttcttatctt
    78541 ttaatttaaa gtacattgct gctactactg ctgtttgtgc aaaagatggt acaaatgctc
    78601 ccactaatat tgtgtcaaac cccatagtca taaggtttga catagctatt ggtactaatc
    78661 cccaatgtag accaaatatt acaagcactt gccacaataa accagttaat gcaccacata
    78721 aaattggtga aaagttaaat aaagctaaaa atccatttcc aactatatta gaagcatagg
    78781 tagctatagg ccctataacc ataaatccca atggtaaaga aactaataaa actgccattg
    78841 gtacaaagaa attctttact acatctggta ttattttagc aaacactttc tccaacttag
    78901 ctgctaataa tactattaaa attactggta ctactgttga agtgtagttc attgctatta
    78961 ctggtaatcc taagaaagtt atatatactg gtgattcaaa tattgttcca gtaaatagat
    79021 tgtataaagg ttgacctgta gatgctagag tatctaattg aatacctgaa tagcataaaa
    79081 ctgcacctat aagcattcca ataaatggtt ttaatttgaa tttcttagca gctgtatatc
    79141 caagaattat tggcatatac tggaacattg catctccaat tgcatttaac ataatatatg
    79201 caccatcagt ttctccatac aaacccaatg ctgtaaatac tgcattaaat ccttttatca
    79261 taccagcagc acacagaact cctaatattg gttgaaaaac tcctgatatt atgtctataa
    79321 acttattaag taatcctttt ggcgcatctg aatctgaatt atctattgta tctcctccta
    79381 atccagccaa atcgcacaca acttcataaa catctggaac atgattacca ataactactt
    79441 ggtattgacc tgcacttttc attacagtaa ctataccatc catttttttt agcacatcat
    79501 catttgctat tgactcatct tttaatttaa aacgtagcct cgttatacag tgagataaac
    79561 tgctaatatt atcctttcct cctacattcg caatgatttc ttttgatagt tgttcatact
    79621 ttctcatttt ttctcctcca ttttcttttt gaaatatgaa ggtttggcca acttaatgtc
    79681 accacccaat atatataaac ctaattatta ggatttatat ctgacttaat acttttactt
    79741 accactcttt caacgtgaat agttaagtat aatttttcct catctgttaa atcgtagttg
    79801 tattttttat gtataaattc atccaacttt tctatgaatt tataagcatt tttatattta
    79861 acttttatta catttaataa atcatcttca ttattttcat gtaaattatt actaacaatt
    79921 cgttctgcaa aatactttaa gtgagtaata aatctatgat aataaactga atcttcatca
    79981 aatactattc tgtaatggta tttaaccata tttgaaattt cttgtattat ttgtgtaatc
    80041 tcatatatag tttttatact ttgatccatt tgtgcattaa ctatatgcag tgctataaat
    80101 ccagcttcat cttctgatag tctaatttca aatttttttt ctatataatc caatgcctct
    80161 aaccctattt taaattcact cttataaaat ctttttatat cccaaagtaa tacatttttt
    80221 acacttactc cttcacgagc tctttctatt gcagtataca tatggtctgt taaagaaata
    80281 taaatactat catttaatct tttccctagt ttttctttag catataaaat tatttcatct
    80341 gataattcca tatatcttat aggaatatct gctattagtt ctttaaattt atcagatata
    80401 tttgggtctg aaagtttgaa tatcttatca attttatcct ttgatatatg ctctcctgta
    80461 cgttttttat aagctaaacc tctccccata actactattt ccttatgatt ttcatcagtt
    80521 gtaataatta cattattatt gagtattttt tcaataatca ttgtgatgcc ccctttatta
    80581 gcattaagtt aaaataaatc ttttttaatt atttagaata tttaaaatgt aatttattac
    80641 ataaaaaaaa acctatttat tacacattaa atagactccc atgagtcctg agtaataaat
    80701 aggtttagct tgtatttaaa caatcactat ccgtttgtat tttattttaa ttattattta
    80761 ttatatgtta gcaaatttat tttttagtgt caactttttc tcaatatttt aattttaaat
    80821 aaattatata aattgaatct tcaaagtact atttttatca ataaacaaaa taaaaaaggt
    80881 attactttct ttaagtaata cccatttatt tttaatttaa gtggtttttc ttaatctcat
    80941 caagtagtcc atcttctaaa taaatttcta atgcacatcc taccattgcc tttactgctt
    81001 tgtgaagttt atcataagct tcctcagaat ttgcataatt tagaaattct ttttcatgaa
    81061 catataccat tggacttata tctaaggcta tttctgtata catagtaggg caaacttgac
    81121 ttacattacc tatatctgta gaacctactg gaccatcttt accttctaat atatctgtta
    81181 tacctgcctc aatcaaatta ttctttgtta tcttttgaag tactttgtta tttattatgt
    81241 tgtcaaaaga attttcaaag tatctataag aaagcttagc tcctgtcatt aactctgcac
    81301 cttttgcaca gtttataact tttttagtta cttcatctaa ataacttctt tcagcagctc
    81361 ttacgaaaaa cttacaggct gctttttctg gaactatatt tggagcctct cctccatttg
    81421 aaactatacc atgtattcta acatctgatt ttacatgttg tcttagtgca tttatcccag
    81481 caaaagtaag ttgtactgca tctagtgcat tgactcccat atgagggtga ctagctgcat
    81541 gtgctgatac cccttcaaaa ctaaactcta atgaatctat cgccaaagcc ttacagttta
    81601 tattattaaa agcttctata tgcatttgat aacttacatc aacatcatca aaagctcctg
    81661 ccttaactaa atcacatttt cctcctgttg tttcttcagc tggtgttcct attagtacaa
    81721 tttttccttt aaaattttct tttaacttac ttaatactat acaagctcct agtgtagatg
    81781 ctgcaatcca gttatgtcca caagcatgag ctggttcttt attttctcca tatccaggaa
    81841 gtgcatcata ctcagctaaa aatgctatgg taggtccatc attatctcct aattcagctc
    81901 taaaagcagt ctccatatta caatatggat aaactgtatc aaatccatat tccttcattt
    81961 tttctactaa gtattttgat gatatgtatt cttcttcccc taattcagga ttgttaaata
    82021 taaaattaca aacttcttca atttcttttc caagttcatt ctctatctca taagctctct
    82081 tctttatact ctctatcata atttacctcc tactagaatc ctagatataa tcctattgtc
    82141 aaaaatgcca ttacaagaat tgttaatact accattaaag gaattacgaa tctaacccac
    82201 tttgaccaag gaatattggc tactgctagt gctcccatta aaacacctga tgtaggtgtt
    82261 atcaagttag ttacacctat accaaattga taagctgtaa ctatcatttg tcttgataca
    82321 tctactaagt cgccaagtgg tgcaagtaca ggtattgtaa gtgatgcaag ccctgatgct
    82381 gatggtatta aaaatgctat taatccttct attaagaaag ttaaatttat aaatatagtt
    82441 tttggtaatc catttaataa atttgctgca gaatttaaaa ttgtatctat tataaatcca
    82501 ttttctgcta ttattacgat tccacgtgca aatgctatac acaatcctgc tgtaattaaa
    82561 tctcctgctc cacttataaa tgaattaact atctcatctt gtttaagccc tgatgctatt
    82621 cctgatatta tacctatagc tgtaaatatc attgcaattt cagttatgta ccattctagt
    82681 cttaaaactc catatatcat aatcgccata cctattgtga aaatggctat taccatggct
    82741 tctctttttg taaattcctt tatatttgta tcactattaa ccattaattc ttgatttagt
    82801 gatatatcgt gtactaaaga ttttttaggg tcttttttaa ctttattggc atacatcata
    82861 acaaatccta tagatatagc catatatatt ataaacataa caactctaaa ctctattcca
    82921 gaacctggta ctatttgtga taatgcttgt gctattccta cagagaaagg attcgtagta
    82981 gctgctccaa atccagctgt tgctcctata aatactgtgg ccactgctgt caatgaatca
    83041 tatcccatac tggtcataag tggaataaat atcatataaa aaggtagtgt ctcttcactc
    83101 attccaaacg tcgtcccacc tagtccaaat agaatcattg aaatcggtat tattaaaaat
    83161 tgaaacttct tcattttatt tacagtatga gctataacag cttctatagc tcctgtttta
    83221 ttaactatcc caaaagctcc tccaactatt aaaacaaatc caactacttc agctgcatct
    83281 ataaatccgt ttataggtgc tgtaaataca tcagtaattc cttgtggatt tgatggtgct
    83341 ttttcataag ttccagctac aacaactgac cttccgtcta tatctactct ttcaaaattt
    83401 ccacttggca ctatccaagt aagaattgcc attaacacta ttagcaaaaa tattattgta
    83461 agtgtctgtg gcatagtaaa ctttttcttt tttaaactgc tcatttttaa tctccccact
    83521 ttttaaatta aatattttat tattgcatcc ctttatccta ttttgtatag atgtaaaaaa
    83581 gctcaacatg gatacatgtt gagctaaatg tgctaaatac aacatacctg catcttccct
    83641 ttatcttgtt taagatagct ctccatcaaa attcgggata attttgatga cagtactgta
    83701 cctattaaat acagtcccag cactagcttc ggacactagc acttcggcac ttactccttt
    83761 tatattgcct cattggtttc caacctcttc aatattaatc ttagtaaatg caacctctac
    83821 ctcaatctgt ttgttagatg aggtaattct tattaatttt tattaattca aagtaattgt
    83881 agcataatat gtcgagattg taaatatttt cagtataata attcttactt tatgatttca
    83941 ttccattttt cacaaataat tttttctcca tataatttaa atactgtagt atattttaaa
    84001 tacacacaaa ctttccacaa atttttaatt attataatac ctttataata aaaaataaaa
    84061 gccatgtaaa cttatcaatt tacacagctt tatatacatt aatctactcc aagtacagct
    84121 ttaagctttg atgctattgt aataactcgt ggaccaaata taacttgaac tgagtttttc
    84181 tttttaacaa ctccacttgc acccaattca tttacccaga agccatcttc atagaatcca
    84241 tcaattgaat ttagctctac cctaagtcta gttgcacagt ttgtaacatt ttttatatta
    84301 ttacttcctc ctaaaccttc tattatagaa tgtacaagct ttgtatcttt atcatctact
    84361 tcctcttcta ctgcattgtt gtatgctgtt ttaccagcat ctacagattg tctttctcta
    84421 tattctttct tactataaag cttaacttct tctgaacttc ttcctggtgt ttttatatca
    84481 aacttcttga ttgcccatgt aaatattata taagtaacta taaaaaatat tggtatcaaa
    84541 aataataatg gtaacgcatc cactttttgt ggttgtaaca aattaggaaa catatttcta
    84601 aatgattctc ccattataga aacattaaac atttctgtaa atacatacgt caatcctgcc
    84661 agtggtacat atgctacaaa atataataat ggtgcaacaa ataggaatgt atactctatt
    84721 ggttccgtta cccctaccaa catggctgtt actattgctg gtatcaatat acttattgct
    84781 tttttcttat tagcattatc agccaactta tacatagcta aagctgctgc tggtaatatt
    84841 gcaaaatgta ttaataaacg acctgttgtg aagttacgag ttatataaga tagtgtatct
    84901 gggtctccca tttgagctaa tcttatatta ttaacaccct cgtaaattgc tccacctact
    84961 tccattgttc cacctactct tgtatattct atagggaatg caattaagtg atgtatacca
    85021 aatggtaata atgctttatc cattgctcca aaagtaaatg ttcctaataa tccactagaa
    85081 cctatccaat taccaagttt agataatgcc aaccctactg gtggccatat aaagtacatt
    85141 gctgtaccca atactattga tgctataaac atcataatca ttgaaaatct tggacctgag
    85201 aaaaaagata atgcactagg aagttctatg tcaacaaatt tgttatgtac tgcactagct
    85261 acaaatccag ctattatagc tccaaatata ctacaatcat atgaaaagat tcctaagaaa
    85321 gaaccatata aagaacttcg actatatgct tctgcctctc ctaatccaga tgccataaac
    85381 gcttctgctg taactgtatc tgaatttata ccatttgctg ctaacaatgt acttataact
    85441 gtgtgcattc ctataaataa aacaattcct cctaatgcac cccatccttt ttccttttta
    85501 gataatccaa aggctatacc tgtaacaaag aatattggta agtatctcat taccataaat
    85561 cctaaatcgt ttattacttt aaagaataca tttataaatg acccttcttt tattagtccg
    85621 ctaagcccta atgcagaaac gttttccata tttgcaaaag ctgaccctaa tcctataaat
    85681 actcctgcta caacaagtaa tataacaggt atcatcattg ctccagaaag tacttgtaat
    85741 ttatccttca tagtattatt tcctccattt ttattgaaat gccaggctat ataatgcata
    85801 tatatatact tctattgctt tgtataatgt atctatactt atattttcat ttgcctgatg
    85861 tgaatttgga ttatccccct ctattgtggg tccaaatgca actccatttt ttaacactct
    85921 tgcataagat gcagctcctt ttgtaaaaag ttcggcttct tttccaaaac cttgtttata
    85981 tgcatttgat aatttattta ttaattcact atctggtttt acatacagta attttaaatc
    86041 cttatatata tcaactatta aattttcttt ttttccaatt tcattaattc tattagttat
    86101 aaactcccaa cttataccct taggatatct aaagtctatt ttcatattca attcattttt
    86161 ctctaagaag atactcatta tacatattgt agaaactccc atatctacat cttctttata
    86221 catccctaat ttttttccat gattatcatc tgtaaagtat gaatttaaaa tatcccttat
    86281 tataacgcct ttatcattta gttttttaat tttctctaaa tcttttgcta aactaaatgc
    86341 acagttatat gacctgtgtg gatttctcga taaagccctt tctcctgtat atcttactaa
    86401 tactttacct tcatctaatt cttctatctc tgtataataa gctaatgatt ctactaaatc
    86461 tttcttatca ttagttttaa aaacagcctc aattttgtca catacaaatc catcttcttt
    86521 gtttgacttt atatcaacta aattgtgatt tctaaattta tctttatcta ttttctttct
    86581 tagattgaag tataaaatac ctttttctcc atttactatt gggaagtttc catctggaga
    86641 aaatgcaaat tttggctgtt cattgacact aaagtaatgc tccatacatt cccaagtcgt
    86701 ctcttcagct ccacccacta tcaatctaat ctttctcttc ggcttttcat taagttctct
    86761 taagaaaagt aatgcatata aaatccctat caaaggtcct ttgttgtcat taactcctct
    86821 accataaaga tagttatctt tttgacatac tttaaaaggt ttactcttcc aaagttcttt
    86881 attatatatt ggcaccacat ctatatgatt aagcacccct actacttctt ctccttctcc
    86941 atattctata tgaattgcat atccatcaaa gtcttttaca acaaaatctt tgtcttttgc
    87001 tatttgaata agcttatcga aggcatttct tatttctatc ccaaatggtt gatttatatc
    87061 tgttgtactt tcatctctaa ttgaaggtat ttcaactaga cttctaatat catttatgat
    87121 attttcttga ttggatttta aataatcaat aattagttct ttgtttacta tcatcttaat
    87181 tatttatcac ccctttatat taattttaca aagcatttca gttcatatct acattataaa
    87241 ttttgaatat tattttttca atatttcaaa tacttctcta agttaccata atgatacggt
    87301 aaacaatcaa cagattatga caaaatcata ctatacctat tactaatatt ttaacttatc
    87361 tattacgtct tttttaatgt aagtttattc caaaaaatac ataaaaaaag atgtagcctt
    87421 agctacatct tcttatatct attcaacttc cattattatg ctattaatat ctacatttcc
    87481 aggttctatc ctatctttta ctgttctctt aacagaatca gcatcatcca ttataactac
    87541 aggagttatt atatttaaat catttgacgt tataaaatct aaatctgctt ccattattaa
    87601 atctttagct tttaccttat ctcctgcctt taccttaaca tcaaacggct ttccttctag
    87661 tgacattgtc tctaaaccta catgtattaa tatatttgta ttatcattac tcttaatcat
    87721 tattgcatgc tttgtatcaa atacattgac tatttcacca tcaacaggag aatataactt
    87781 accttcactt ggtattattg ctactccatc tcccatcatc ttttgggcaa aaactgcatc
    87841 tggaacatct tctaagttca ctaaatttcc cttaaaaggg ctatatattt tctcaatctt
    87901 attttctttt ttcttaaata tattaaacat aacacactct ccacattata aaattttatg
    87961 ataatatttt tcttaaagct tttgctacac catcatttac attagtatca gttacaaaat
    88021 ctgccataga ttttacttca tctgtagcat ttcccatagc aataccaaga cctgcaaatt
    88081 taatcatgga tatatcattt tcattatcac ctatacaaat aacttctttg ctatctatac
    88141 ctaatatatc acaaaatttt ttaactgcaa taccttttga agtaccttta ctcataactt
    88201 caaagtttat ctttccagaa cttactactt ctaaatcttc ttgtttttta aattcttcct
    88261 ttgcttctct caaagaatct acattttctg agaaaagtat acattttaaa atttcattat
    88321 cagctttttc taataaagtt tcacaacttg cattttctat tatttcaatt ctgtcttctt
    88381 ctttattttt actatttatt aatctatatg gatgttcttc acctatttca ttgttggata
    88441 taactatttt acagccttta aaatgtttgt ttaaattata cttttcacct attgtataga
    88501 ttttctttag agcttctttg ctcaaaacct tcttatactc atatcccagt aatttaaaat
    88561 atgtcccatt agttgatata atatatatat catcccctaa aacacttgta aaatatttca
    88621 tagcattata aggtcttccc gtaactaagg ctaccttgat acccttttcc atgacttctt
    88681 ttagtgcttt aatattttct tctgatactt caaatccttt ccccatcaaa gtaccatcca
    88741 tatcagtaca aattaattta tatcgcattt gtatcacatc ctagtaagat ttttctaata
    88801 tttcaacaag gtcttctttc tttccaaaag gtaaaaatcc taaaactgga cagcttgtta
    88861 tttgttctaa ttgttccttt gttacattaa actcagacat ttttgtctta agtcccactc
    88921 tctttaaaaa actttctatt tcatttccta aagttttagc tgcttcatca tcttccactt
    88981 tttctaattc ttggtttagc attctcgcta ctttggcaaa tttctctata ttatccttat
    89041 agaacttttc tgcaaatttt gggaacacta tagccaaagc ctcaccatga ggaatatgtg
    89101 taactcctcc tattatttca cttagtggat gtggtgctgc tgctccagca tttgccagtg
    89161 aacttcctcc taatgtatct gctactgcta actttgttct gtattctata ttatttttat
    89221 cttccattac tttaggtaga tagttaatga ctaattccat agatttttca gacattatct
    89281 ctgtaaaatc attagcattt ggatttatat aactttcaaa tgcatgggta aaagcatcaa
    89341 atgctgttga tgcagtaatt ctctctggca gagttaacat aagctctggg tcaactatac
    89401 attcttttga gaaacaattt tgatgaaata ttgtattttt ctcgcttcct ctcgatatta
    89461 ctgctgcttg tgtaacttgg cttcctgttc cagaagtagt tgatacagct attaatggta
    89521 attctttttc acttacctta tcgtatattt taaatggatt tgtatatgta ctaaacatat
    89581 aatcccaatc tattttttct aaaccaaaag tcaatgctaa tacttttgca gtatctatac
    89641 ttgaacctcc tccaacagct aaaacaacgt ctacagattc ttttttagct aattcaaacc
    89701 cttcgtttat taattctaca gttgggtttg gctctactct ctgaacctcc catgactaaa
    89761 gtcacagggt tcctgcttca cagaattttg catactaaca tatgtcttac taattctcca
    89821 caggccatcc ccgtagttcc tacggttctt acataagtta tttattttga attgttatta
    89881 gtcttaatcc ttcttttaat atatttatac ttgcatttat atctctatcg tgagtttcat
    89941 tacaactagg acaaatccat tctcttatat ttaagtcctt cacttcctcg tttttatacc
    90001 cacatttatt gcatatttgt gaacttgcaa agaatttacc tacctttaca atttgtctac
    90061 catgccaatt agccttgtat tctaattgac gaataaactc tgaccatgat acatcagaaa
    90121 ttaagcgaga tagtttacga tttctaatca tattctttac ttgtaaatct tctatgcaaa
    90181 taatatcgtt ctcttttatt aatttagtag atagtttttg tagaaaatca tttctttgat
    90241 tagctatatg ttcttgaagt cttgcaactt ttaatcttgc tttatttcta tttaaactac
    90301 cgattgtttt tctcgataat tctctttgta atttagcaag tttgtttaat gacttcttaa
    90361 gatacttagg attttctata aattctccac aacttgagat acaaaattct ttaat
//
LOCUS       DAEPXW010000002        84022 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.002, whole genome shotgun sequence.
ACCESSION   DAEPXW010000002 DAEPXW010000000
VERSION     DAEPXW010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 84022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84022
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.002"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(97..870)
                     /locus_tag="KRM55_000072"
     CDS             complement(97..870)
                     /locus_tag="KRM55_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBH1592350.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(870..1256)
                     /locus_tag="KRM55_000073"
     CDS             complement(870..1256)
                     /locus_tag="KRM55_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1592351.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1281..1598)
                     /locus_tag="KRM55_000074"
     CDS             complement(1281..1598)
                     /locus_tag="KRM55_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBH1592352.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1610..1870)
                     /locus_tag="KRM55_000075"
     CDS             complement(1610..1870)
                     /locus_tag="KRM55_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBH1592353.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1870..2166)
                     /locus_tag="KRM55_000076"
     CDS             complement(1870..2166)
                     /locus_tag="KRM55_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1592354.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2235..4661)
                     /gene="gyrA"
                     /locus_tag="KRM55_000077"
     CDS             complement(2235..4661)
                     /gene="gyrA"
                     /locus_tag="KRM55_000077"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBH1592355.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4681..6582)
                     /gene="gyrB"
                     /locus_tag="KRM55_000078"
     CDS             complement(4681..6582)
                     /gene="gyrB"
                     /locus_tag="KRM55_000078"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBH1592356.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6583..7698)
                     /gene="recF"
                     /locus_tag="KRM55_000079"
     CDS             complement(6583..7698)
                     /gene="recF"
                     /locus_tag="KRM55_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBH1592357.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7716..7922)
                     /gene="yaaA"
                     /locus_tag="KRM55_000080"
     CDS             complement(7716..7922)
                     /gene="yaaA"
                     /locus_tag="KRM55_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBH1592358.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8059..9165)
                     /locus_tag="KRM55_000081"
     CDS             complement(8059..9165)
                     /locus_tag="KRM55_000081"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBH1592359.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYTYLLLPVRISSNI"
     gene            complement(9407..10729)
                     /gene="dnaA"
                     /locus_tag="KRM55_000082"
     CDS             complement(9407..10729)
                     /gene="dnaA"
                     /locus_tag="KRM55_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBH1592360.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11385..11522
                     /gene="rpmH"
                     /locus_tag="KRM55_000083"
     CDS             11385..11522
                     /gene="rpmH"
                     /locus_tag="KRM55_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBH1592361.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11600..11944
                     /gene="rnpA"
                     /locus_tag="KRM55_000084"
     CDS             11600..11944
                     /gene="rnpA"
                     /locus_tag="KRM55_000084"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBH1592362.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11976..12227
                     /gene="yidD"
                     /locus_tag="KRM55_000085"
     CDS             11976..12227
                     /gene="yidD"
                     /locus_tag="KRM55_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBH1592363.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12259..12966
                     /locus_tag="KRM55_000086"
     CDS             12259..12966
                     /locus_tag="KRM55_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH1592364.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12935..13564
                     /locus_tag="KRM55_000087"
     CDS             12935..13564
                     /locus_tag="KRM55_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBH1592365.1"
                     /translation="MRKSLKLIKSKSKEEAISKVIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13676..15055
                     /gene="mnmE"
                     /locus_tag="KRM55_000088"
     CDS             13676..15055
                     /gene="mnmE"
                     /locus_tag="KRM55_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBH1592366.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15150..17045
                     /gene="mnmG"
                     /locus_tag="KRM55_000089"
     CDS             15150..17045
                     /gene="mnmG"
                     /locus_tag="KRM55_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBH1592367.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTNSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVDKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGDDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRR
                     TRGGKGE"
     gene            17038..17757
                     /gene="rsmG"
                     /locus_tag="KRM55_000090"
     CDS             17038..17757
                     /gene="rsmG"
                     /locus_tag="KRM55_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBH1592368.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17920..18705
                     /gene="noc"
                     /locus_tag="KRM55_000091"
     CDS             17920..18705
                     /gene="noc"
                     /locus_tag="KRM55_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBH1592369.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18840..19613
                     /locus_tag="KRM55_000092"
     CDS             18840..19613
                     /locus_tag="KRM55_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBH1592370.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19615..20478
                     /locus_tag="KRM55_000093"
     CDS             19615..20478
                     /locus_tag="KRM55_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBH1592371.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20511..21653
                     /locus_tag="KRM55_000094"
     CDS             20511..21653
                     /locus_tag="KRM55_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH1592372.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(22078..22977)
                     /locus_tag="KRM55_000095"
     CDS             complement(22078..22977)
                     /locus_tag="KRM55_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1592373.1"
                     /translation="MSIYGYTIFETVLEQNSFIKAASILNLTPSAVSHAIAKLEIDVG
                     FQLFIRNRNGISLTREAEKILPHIRILLHSNEILEQEINRISRSESGIIRIGTFNSIT
                     INWIPEIMKSFRQEHPNIEIHILQGNYINILEWIETSIVDLAFISNTVLPPHIESIPL
                     HKDRIICVFPKGFVPCNPGYVTIEDIQNMSFVMPKKDYDQEVEKILREYHLNVYSQFH
                     IDTDSAIVAMVEAGFGIAILSELIYKSCVGNVDTYPFVPEHYRVISLAYPNSQYDSFA
                     VQKMKEHIVSYTKEKGFFNFKSF"
     gene            23247..24443
                     /locus_tag="KRM55_000096"
     CDS             23247..24443
                     /locus_tag="KRM55_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1592374.1"
                     /translation="MVKFAKRMENMKNSANIVRNLFNSMTDPEIISFGGGAPAIEALP
                     VDIVREISNEVLAKNKRGIEALQYSHPYGLKDLREAVAQKLLEPKGVHASPEDIMIVN
                     GGLETMNLICQVFIDPGDVILVESPTFVHCVEIFEMFQAKCIAVDMDEHGIIPEDIER
                     KIQKHHPKMVYVIPTFHNPTGRTLTTERRKILAGIGSKYDVLILEDDPYRDLRYSGEE
                     LPPIKAFDQTGHTILANSFSKIFSPGARLGYVLAEHAIIERLLDAKTATNSHTSAISQ
                     VLCAEFFNRGYFDEHLKNIRDIYRERRDVMIESIDKYLPKGTKRVFPDGGLFTWVELP
                     ENINTTELLKEAVEHKVAFVAGEGFFTEGGGKGRNCMRISFGNVPPEKIRIGMERLGQ
                     LIASKM"
     gene            24511..25257
                     /locus_tag="KRM55_000097"
     CDS             24511..25257
                     /locus_tag="KRM55_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBH1592375.1"
                     /translation="MTNKVPNLWNQLENLKKSYKWVDLSREVSPETPHWTGFPAMEVE
                     PFYLLDRGDGFNVNKYTLVTQYGTHVDAPIHFVADRKYLDEYTPMDMVLPLCVIDKSD
                     EVAKNSDYVVTVEDIQAWEKEYGNIPEGAFVAFRSDWSKRPDDSLDNYDSDGNKHFPG
                     WSIEALQYMVEKRNIAAIGHETCDTDAPILSNVSGYQAETYILGENRYQVEFLVNLSE
                     LPAIGAIIFVTFPRIHKASGFTARCFAICP"
     gene            25290..25793
                     /locus_tag="KRM55_000098"
     CDS             25290..25793
                     /locus_tag="KRM55_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBH1592376.1"
                     /translation="MSKKAMFVWCVGLGLLDGIYCILCSYLPHIQNYMWIGFISLPIY
                     FCGGAKLEEMPKYFCCAASGIFWGGLTLVVLDIGFISNIHLNMLVFVTIVVCIACFVH
                     LGVLTENVWKGLFSSCPMMFGGFAAIFSQGLAEWFWVLVTLTLGLIFGCIMASISTPI
                     TKWIDKN"
     gene            26041..26876
                     /gene="panB"
                     /locus_tag="KRM55_000099"
                     /pseudo
     CDS             26041..26876
                     /gene="panB"
                     /locus_tag="KRM55_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
     gene            complement(28394..28969)
                     /locus_tag="KRM55_000100"
     CDS             complement(28394..28969)
                     /locus_tag="KRM55_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBH1592377.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            29229..30521
                     /locus_tag="KRM55_000101"
     CDS             29229..30521
                     /locus_tag="KRM55_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1592378.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            30626..31228
                     /gene="yedF"
                     /locus_tag="KRM55_000102"
     CDS             30626..31228
                     /gene="yedF"
                     /locus_tag="KRM55_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBH1592379.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            31301..31564
                     /locus_tag="KRM55_000103"
     CDS             31301..31564
                     /locus_tag="KRM55_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBH1592380.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            31579..31764
                     /locus_tag="KRM55_000104"
     CDS             31579..31764
                     /locus_tag="KRM55_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBH1592381.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            31867..33063
                     /locus_tag="KRM55_000105"
     CDS             31867..33063
                     /locus_tag="KRM55_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1592382.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            33277..33555
                     /locus_tag="KRM55_000106"
     CDS             33277..33555
                     /locus_tag="KRM55_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBH1592383.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            33592..34026
                     /gene="ssb"
                     /locus_tag="KRM55_000107"
     CDS             33592..34026
                     /gene="ssb"
                     /locus_tag="KRM55_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1592384.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            34045..34272
                     /locus_tag="KRM55_000108"
     CDS             34045..34272
                     /locus_tag="KRM55_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBH1592385.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            34415..34735
                     /locus_tag="KRM55_000109"
     CDS             34415..34735
                     /locus_tag="KRM55_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH1592386.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            34743..35699
                     /locus_tag="KRM55_000110"
     CDS             34743..35699
                     /locus_tag="KRM55_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBH1592387.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILYLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            35710..37704
                     /locus_tag="KRM55_000111"
     CDS             35710..37704
                     /locus_tag="KRM55_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBH1592388.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            37705..38154
                     /locus_tag="KRM55_000112"
     CDS             37705..38154
                     /locus_tag="KRM55_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBH1592389.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            38173..39501
                     /gene="dnaB"
                     /locus_tag="KRM55_000113"
     CDS             38173..39501
                     /gene="dnaB"
                     /locus_tag="KRM55_000113"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBH1592390.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            39706..40014
                     /locus_tag="KRM55_000114"
     CDS             39706..40014
                     /locus_tag="KRM55_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592391.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            40096..41385
                     /locus_tag="KRM55_000115"
     CDS             40096..41385
                     /locus_tag="KRM55_000115"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBH1592392.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            41711..41786
                     /locus_tag="KRM55_000116"
     tRNA            41711..41786
                     /locus_tag="KRM55_000116"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41744..41746,aa:Lys,seq:ttt)
     gene            41793..41867
                     /locus_tag="KRM55_000117"
     tRNA            41793..41867
                     /locus_tag="KRM55_000117"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41826..41828,aa:Glu,seq:ttc)
     gene            41872..41947
                     /locus_tag="KRM55_000118"
     tRNA            41872..41947
                     /locus_tag="KRM55_000118"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41905..41907,aa:Val,seq:tac)
     gene            41981..42055
                     /locus_tag="KRM55_000119"
     tRNA            41981..42055
                     /locus_tag="KRM55_000119"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42013..42015,aa:Thr,seq:tgt)
     gene            complement(42438..43430)
                     /locus_tag="KRM55_000120"
     CDS             complement(42438..43430)
                     /locus_tag="KRM55_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1592393.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(43439..44497)
                     /locus_tag="KRM55_000121"
     CDS             complement(43439..44497)
                     /locus_tag="KRM55_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH1592394.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            44622..46085
                     /locus_tag="KRM55_000122"
     CDS             44622..46085
                     /locus_tag="KRM55_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBH1592395.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            46187..46984
                     /locus_tag="KRM55_000123"
     CDS             46187..46984
                     /locus_tag="KRM55_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1592396.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            46997..49099
                     /locus_tag="KRM55_000124"
     CDS             46997..49099
                     /locus_tag="KRM55_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBH1592397.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            49167..49646
                     /gene="rlmH"
                     /locus_tag="KRM55_000125"
     CDS             49167..49646
                     /gene="rlmH"
                     /locus_tag="KRM55_000125"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBH1592398.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            49795..50106
                     /locus_tag="KRM55_000126"
     CDS             49795..50106
                     /locus_tag="KRM55_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1592399.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            50154..50471
                     /locus_tag="KRM55_000127"
     CDS             50154..50471
                     /locus_tag="KRM55_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1592400.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            50684..51385
                     /locus_tag="KRM55_000128"
     CDS             50684..51385
                     /locus_tag="KRM55_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1592401.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            51609..52910
                     /locus_tag="KRM55_000129"
     CDS             51609..52910
                     /locus_tag="KRM55_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1592402.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            53047..54141
                     /locus_tag="KRM55_000130"
     CDS             53047..54141
                     /locus_tag="KRM55_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH1592403.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIILLDFIEPWSKFKLILEGE"
     gene            54143..55276
                     /locus_tag="KRM55_000131"
     CDS             54143..55276
                     /locus_tag="KRM55_000131"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBH1592404.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELRRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            55294..56403
                     /locus_tag="KRM55_000132"
     CDS             55294..56403
                     /locus_tag="KRM55_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBH1592405.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            56468..57208
                     /locus_tag="KRM55_000133"
     CDS             56468..57208
                     /locus_tag="KRM55_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBH1592406.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGILSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            57213..58205
                     /locus_tag="KRM55_000134"
     CDS             57213..58205
                     /locus_tag="KRM55_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBH1592407.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYITTGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(58393..59274)
                     /locus_tag="KRM55_000135"
     CDS             complement(58393..59274)
                     /locus_tag="KRM55_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1592408.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            59547..60935
                     /locus_tag="KRM55_000136"
     CDS             59547..60935
                     /locus_tag="KRM55_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592409.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            60963..61916
                     /locus_tag="KRM55_000137"
     CDS             60963..61916
                     /locus_tag="KRM55_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1592410.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            61976..62200
                     /locus_tag="KRM55_000138"
     CDS             61976..62200
                     /locus_tag="KRM55_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592411.1"
                     /translation="MNEKSSFKQIEIILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            62193..62705
                     /locus_tag="KRM55_000139"
     CDS             62193..62705
                     /locus_tag="KRM55_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBH1592412.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            62737..63591
                     /locus_tag="KRM55_000140"
     CDS             62737..63591
                     /locus_tag="KRM55_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBH1592413.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            64125..64919
                     /locus_tag="KRM55_000141"
     CDS             64125..64919
                     /locus_tag="KRM55_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1592414.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            65023..65829
                     /locus_tag="KRM55_000142"
     CDS             65023..65829
                     /locus_tag="KRM55_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1592415.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            65891..66412
                     /locus_tag="KRM55_000143"
     CDS             65891..66412
                     /locus_tag="KRM55_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1592416.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            66827..68914
                     /locus_tag="KRM55_000144"
     CDS             66827..68914
                     /locus_tag="KRM55_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1592417.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMDDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLVEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            68929..69216
                     /locus_tag="KRM55_000145"
     CDS             68929..69216
                     /locus_tag="KRM55_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1592418.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            69243..70514
                     /locus_tag="KRM55_000146"
     CDS             69243..70514
                     /locus_tag="KRM55_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBH1592419.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            70572..71171
                     /locus_tag="KRM55_000147"
     CDS             70572..71171
                     /locus_tag="KRM55_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1592420.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQEYLKWHPAGSLGKSIREGI"
     gene            71176..72081
                     /gene="dapA"
                     /locus_tag="KRM55_000148"
     CDS             71176..72081
                     /gene="dapA"
                     /locus_tag="KRM55_000148"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1592421.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKSQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            72187..72819
                     /locus_tag="KRM55_000149"
     CDS             72187..72819
                     /locus_tag="KRM55_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBH1592422.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGLNIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNVRKI"
     gene            73296..75803
                     /locus_tag="KRM55_000150"
     CDS             73296..75803
                     /locus_tag="KRM55_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1592423.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            76145..78307
                     /locus_tag="KRM55_000151"
     CDS             76145..78307
                     /locus_tag="KRM55_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBH1592424.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            78312..78929
                     /locus_tag="KRM55_000152"
     CDS             78312..78929
                     /locus_tag="KRM55_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1592425.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYKKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLDLSEQADRVIKL"
     gene            79118..79462
                     /locus_tag="KRM55_000153"
     CDS             79118..79462
                     /locus_tag="KRM55_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBH1592426.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            80032..80898
                     /locus_tag="KRM55_000154"
     CDS             80032..80898
                     /locus_tag="KRM55_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1592427.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPINK
                     ESGKPCINLQPDFKCSVHNSLIKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESMMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            81011..81415
                     /locus_tag="KRM55_000155"
     CDS             81011..81415
                     /locus_tag="KRM55_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBH1592428.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEVIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            81579..82028
                     /locus_tag="KRM55_000156"
     CDS             81579..82028
                     /locus_tag="KRM55_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1592429.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(82184..82561)
                     /locus_tag="KRM55_000157"
     CDS             complement(82184..82561)
                     /locus_tag="KRM55_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1592430.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            82823..83740
                     /locus_tag="KRM55_000158"
     CDS             82823..83740
                     /locus_tag="KRM55_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBH1592431.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
BASE COUNT        32054 a         9950 c        13951 g        28067 t
ORIGIN      
        1 tttcaatgtt cgtgtttatt tcttgttcct tttttcaagg acaagtaata ctataccatc
       61 tttaaaacag taggtcaata ctttttttat atttttttat aaattttttt catattcttt
      121 tttcagcttc tctactacct ttttctctag tctagaaaca gtcatctgtg atatccctag
      181 ttctttagct atactagatt gtgttttatc aaagaaaaat ctatctttaa aaattttaac
      241 ttctaattca tttaaagttt caataaactt attaataaaa tcttcatact ctatacttcc
      301 aaagttacct tcttcttttc caatcttatc aataagagtt atatctttat cctctgaatc
      361 atcattactt gatgaatcca aagacattgg ttgatatcca taagaagcct ccatagcctc
      421 taaaacatct tcttcactaa cgcctatata atcagctata tcttttacct ttggatgctt
      481 cttattttct tgttctaatt taatcttcgc atcacttatc tttttgctta attcctgtat
      541 tcttcttggg actctaagtg tccatacttt atctctaaaa tactttttta tttctcctac
      601 tatagttggt gttgcaaagc tggagaactc aaatcctttc tcaacatcat atctatcaat
      661 agcataaatt aatgccaatg aagcaacttg atatatatct tcaaaatcaa cacctttgtt
      721 tatatacttc ttagctaaca atcttgctaa atacagatgt ctttcaataa gaatatttct
      781 aatgtctaca tttttatttt tattatataa attaaatagc tcttttgtat ccatatttag
      841 gtaatgtgta gcattagcta catttttcat taaatatcaa ctcctaaata tttagtcatt
      901 tttatttttg tcccttgatt atgttctgat tcaatatcta catcatccat taaagtttta
      961 attataaaca atccaagacc actctctttt ggattctcta aatctggtgt acttattgag
     1021 ctaacatcat atccttttcc attatcttga atttctatat taattgcatt atctaaaata
     1081 ttaaatacta tattaaatac atcatcttta ctgtgtttta ttgcatttgt acatgcttca
     1141 gatactgcta cctttatatc ttctatatca tctattggaa aacccatctt attggcaatt
     1201 ccagatgctg ttaatcttat tatactaaca taatctggat ttgtagtaat ttccatcttt
     1261 atagtctcac aagccaaagt ttatccctcc actttaaata ttttatctag acctgttata
     1321 gtaaaaatct ttcttacgtt actcttagga tttactatgt atatctcttt ttcatttatt
     1381 tttaattttt ttaatacacc tatcatagct cctaagcctg ttgagtctat ataatctaaa
     1441 tctttaagat taatctttac atctaacata tttttttcta ttaaagcatg taaatgttcc
     1501 tttagtttat ctgctgtaga aacatcaagt tctccatcaa gacaaacatt ccaaaattta
     1561 ttttgtgaat ctaaatttga atcaatattc atagacatgt aaaaacctcc tatttccttt
     1621 taataatttt aaatatattt cctatactca atattttatt aattacataa actatatcat
     1681 ctattccctt tgatattgat gatgcatttt caacaatatc ttgtatatgt ctttcattat
     1741 aatctacaat cttatatgcc ttttcaacaa ccttatttat gctgtttaga gttttagcta
     1801 aataaattgc tactataaga gcagagcttc ctactaacac tgctccaatt tgccaccccc
     1861 atgcattcat tagttaacat ctccctcatc atcaaagctt ttacttatta ctatatcttc
     1921 ttctgaaatc tttatatctt cttcattatt atcatcatcc actaaattta ttattctctc
     1981 tttaacatca ttaaatgttt catgtagaac ttcttttgga ttttctttaa catcattaaa
     2041 cttctctttt gtttcttttc ttagttcaga acctttttta ggtgcaaaaa acataccaaa
     2101 tataaaccct aaaatagctc ctaataataa aaatccacct tttttacaac ttcttttatt
     2161 gcacataaca attactcctt tcaattttaa atttttatct aactacatta tacaaaaaga
     2221 ataggatatt tatcctattc ttcttcaata tttattttgg caatcgaaac tacattgact
     2281 tcatcattcg tcttcattaa tttaacacca cttgtaactc ttccaaacag tgatatttca
     2341 ttgactctta ttctaataag aactccatca gaatttataa tcattatctc atcatcttcg
     2401 ttgaccatat ctgcacctac aattgtacca gttttttcag atatattata agttttaatt
     2461 cctttaccag ctcttatttg acttctatac tcttctatat ttgttctctt tccaaaacca
     2521 ttcttactta caactaacac atctgtacct ttactgcaaa ggttcataga cacaacaaaa
     2581 tcttctttac ttaaagttat accttttaca cccattgctg ttctacccat atatcttata
     2641 tcattttcat caaatcttat agacatacct tctttagtta ctaaaagtac ttcttgtttt
     2701 ccatctgtaa gttctactcc aataagctca tcatcatctc ttaaacctat agcaataaga
     2761 ccagatttat ttatattttt gaactcttct ctcttagtct ttttaacaat accttttttc
     2821 gttgcaagta ataaatattc attttcatca ttaccatcaa taggtattag agtagcaatt
     2881 ttctcatctg ctgacaattg aagtaaattc actatagcag tacctttagc ctgtctctta
     2941 ccttctggta tttcatatgc atttaattta aatactctac ctttatttgt aaagaataat
     3001 agtctactat gagtagttgt agttaccaag tgccttacaa aatcttcttc tctagttgta
     3061 agtgctgaaa tacctcttcc accccttttt tgactcttat aagtatcaga tggaagcctt
     3121 tttatatatc caaagtgagt aagagttatt gctatttctt catcacttat aagatctctc
     3181 atatctattt cgccttcagc atgtcttatt tctgttcttc tctcatcaga gtaattttct
     3241 tttattattg taatttcatc ctttattaca tttaaaagta atctttcatc agctaaaatc
     3301 tcttttaatc tatttatctt cttgattaaa tcttcatatt cagcttctat cttatctctt
     3361 tctaaacctg taagtctttg aagtctcata tctaatatag cttgtgcttg gatttcagtt
     3421 aatttgaatt tttctattaa acctagctta gcttcttgcc cagtctttga agctcttatc
     3481 aagcttataa cagcatctat attatctaaa gcaatcttta atccttctaa aatatgtgct
     3541 cttgcttcag ctttatttag ttcaaattta gttcttcttg taacaacatc ttcttgatgt
     3601 ttaatataat gatataatat ttgtttaaga tttaaaactc ttggctgacc atctacaagt
     3661 gcaagcatta ttatactaaa agtatcttcc atttgagaat gtttatacaa attatttaat
     3721 actatattag cattagcatc cctctttaat tctataacaa ttctcatacc atttctatta
     3781 ctttcgtctc ttaggtctga tataccttct attctctttt ctttaactaa ctctgctatt
     3841 ctttcaacca gtttagcctt atttacttga taaggtattt ctgtaactat tatttgctgt
     3901 tttccttttg gtagctcttc tataaaagct ctagacctaa ctttaacttt tcctcttcca
     3961 gttctgtatg cttctgctat actttctttt cccattataa ttgcagctgt agggaaatct
     4021 ggtccttgaa caaattttat taaatcatct acactacact ctggattatc tatcaaatat
     4081 acagttgcat caattacttc tgctaaatta tgtggaggta ttgaagttgc cataccaaca
     4141 gctataccat ttgagccatt tactaataaa ttaggatatc tagctggcaa tactgaaggc
     4201 tcttttaacg actcatcaaa gtttggttta aagtctacag tttccttttc aatatctctc
     4261 agtagttcta atgataattt actcatttta gcttctgtat aacgcatagc agctggtgaa
     4321 tccccatcaa cagaaccaaa gttaccatga ccatctacta aaagtgctct agttgaaaaa
     4381 tcttgtgcca ttcttaccat agcataataa acagcagtat ctccatgagg atggtactta
     4441 cctaaaacgt ccccaacaat acgagctgac ttcctgtatg gtttatctgg agttaaattt
     4501 aactcactca ttgaatataa tattcttcta tgaactggct ttaaaccatc tctaacatca
     4561 ggaagagcac gtccagctat aacactcatt gaataatcaa tatacgattt tttcatttct
     4621 tccgctattt caatagggag tattttgtta ttttcttcca tgtatactaa tcccctctct
     4681 ctatatatct aagtttctaa caaatcttgc attttcttct ataaattctt ttcttggagc
     4741 aaccttatca cccataagca ttgaaaatac ttcatctgca attgcagcat cttctacagt
     4801 aacttgtaat aaagttcttg tctcaggatt catagttgtt tcccataatt gctctgcatt
     4861 catctctcca agacctttgt acctttgaag ttcaacacca tttcttccaa tttcatctaa
     4921 taagatattt aactctttat ctgagtaaac ataatgttcc ttcttttgct ttgtcacttt
     4981 atataaaggt ggctgtgctg cataaacata cccctcatct ataagaggtc tcatatatct
     5041 aaagaagaat gttaataata aagttcttat atgggctccg tctacatcag catcggtcat
     5101 aattataatt ttatgatacc tagccttatc tatatcaaaa tcttctccaa taccacaacc
     5161 ataagctgtt atcatatttt ttatttcatc tgaagatagt atcctatcta gtcttgattt
     5221 ctcaacatta agtattttcc ctcttaatgg aagtatagct tgactatttc tatctctacc
     5281 ttgtttagct gaacctcccg ctgaatcccc ttcgactaag aatatttcac ttttagatgg
     5341 atctttttct gcacaatctg caagttttcc aggtaaagat gtactttcta atacactttt
     5401 tctccttgtt aattctcttg ctttttttgc agcttctcta gctctttgtg ctcttaaagc
     5461 tttatcaact atgattcttg ctgttgatgg gttttcttct aggaaagacc ccagttcatc
     5521 aactgttaca ctatcaacta tacctctcat aaagctatta cctagctttg ttttagtttg
     5581 accttcaaat tgaggttctg gtaatttaac tgatactact gctgtaagac cttctcttat
     5641 gtcttcacca agtaggttaa catcattttc ctttaaaaat ttatttctct tagcataatc
     5701 atttacagtt ttagtaagag ctgctttaaa tccacttaaa tgagaaccac cttcgtgtgt
     5761 atttatattg tttgcaaaag aatatatgtt ctctgtataa ccatctgtat attgcatagc
     5821 tagttcaaca aaacaatcat caaccttttt atctatataa actatgtcat catgtatacc
     5881 agttctagat ttatttaaat acttaatgta ttctaccaaa ccacctgtat agtgaaattc
     5941 ttttcttttt tcttgtcctt ctcttttatc ttcaaatact atttttattc ctttattcaa
     6001 gaaagaaagt tctctaagcc tatactccaa tgtttcatat ttaaactcta tttcatcaaa
     6061 tattgtctca tctggcataa attgaatcat tgttccttta tcttgagatt ctccaactac
     6121 ttcaagctta gatgttggca atcctttctc atatgtctgc ttatatatct ttccgtttaa
     6181 ataaacctct gctaccatcc attttgacaa tgcattaact acagaaacac caactccatg
     6241 aagacctcca gatactttat atcctccgcc tccaaacttt cctcctgcat gaagattagt
     6301 taatactgtt tctaaagttg atttaccagt tttaggatgt atttcaacag gtatacctct
     6361 tccgttatct tttactaaaa cactgccatc ttcattaata gatacatata tgtctgaaca
     6421 atatccttgt aaagcctcat ctatactatt atctacaact tcataaacta agtgatgtaa
     6481 acctctaggg cttgtactac caatatacat acctggtctt tttctaacgg cttctaatcc
     6541 ctctaatact tgtatctgac ttgcaccgta ttcttgtttc atttaatttc ctccattctc
     6601 tatgctaata acatcgccat tttcaatatt aaatattgta acattttttt catcaaatat
     6661 ttttttatgt gaaacttcag cacttgttat aaacatttga acattgctta aattatttac
     6721 taaaagtttt tgtcttgctt catctaactc actaaaaaca tcatctaaaa ttaatactgg
     6781 atattcttca acttcatttt ttattaattc tatctctgat aactttaatg atattgaagc
     6841 agttctttgt tgaccttgtg aaccaaaaag tcttgcatct aaatcattta tgaatatatt
     6901 taagtcatct ttgtgtatac catatctggt agtcttagat tctatatcat taggtctatt
     6961 cgatgacaac ttggctaaaa atttattata tactgtatct atagtatctt catcagttat
     7021 atttatttga tttttatatc gaattgataa tctttcaact ccattagtca aattcatatg
     7081 catattttca gatatattag ctatcttttt tataaagtct ctacgcaaaa tataaatata
     7141 acttccatac tttgctaacg tatcatcata tacatctaat aaagcttcat caacatgtat
     7201 atttttaagc accctactcc tttgagaaag tgttttatta taattggtaa gatatttata
     7261 atatttaggt ataatctgac taatctcttt gtctataaat gcccttcttt ctttaggacc
     7321 ctctttaacc aaccttaaat cctcaggaga aaatataaca acatttaagt tgccaagtag
     7381 ttcttgtatc ttttgtaaag gaactttatt tattcttatc ccttttttat cttttccaat
     7441 aattagctct attagactat atttattata ttttgaaaaa cttcctccaa tatataagtt
     7501 ttcactatta aatctaacca tttctttatc tttgttagtc ctaaatgatt ttccaaaaga
     7561 aagcatataa atagattcta ctatatttgt ctttccttga ccatttttac caacaagtag
     7621 atttactttc ccattaaatt ccagatgcaa ctttttataa tttctaaaat taacaagttg
     7681 caaactttta agtttcacaa aaagttctcc tttttttaca atacttttat tttagttcct
     7741 tctatttcaa ctatatctcc tgattttatc ttttttcctc ttcttaattc tatttcatca
     7801 tttactgtca ctaaaccttc ttgaattaaa aattttgcat gacctcctgt tgatgcaatc
     7861 tctgctaatt taagaaattg atccaacttt atatattctg attctatagt tatttcagtc
     7921 ataatagttc ctccttgtca ctattttaaa caaattccta ttgatacact aaaagtatat
     7981 tataccataa atatgcttat aaaaggagtt gtctaagatt agaaaaattt tctacaaaag
     8041 acaactcctt catgtctgct atatatttga tgatattctt actggaagca gtaagtaagt
     8101 ataattaaca tcatctgttg gtttaattat acaaggattt acatttgtag taaattctat
     8161 aaatatttcc tcattatcta tatttttcaa accttcgata aaatatctag aattgaaagc
     8221 tatatctagg taatctccat ctaaatctat ttcaacttct tcatacacat ttcctttttc
     8281 tgtattagaa gtaattgcca ttactttatc tcttatagat aactttataa gattattttt
     8341 ttctgattga gacaataaag acgctctctc tatactattt aaaagttcct tagtatttaa
     8401 tttaactctg ctgttatgtt ctcttggcaa taatttttta taatcaataa aatctccttc
     8461 aagcaatctt gtaataattt ttgtatcatt aattataaaa atagcatttt tttcgttaaa
     8521 tccaacttta acattatcct ctccagaaag caaactattt acatctataa gtgtctttcc
     8581 aggaattatg acttttatat tttcagttaa actatcaacc gaacaacttt ttacagctaa
     8641 tctatatcca tcaattgcta ctaaatttaa gtttctatct acaatttcta aaagttctcc
     8701 cattaaaaca ggttttgttt ggtcctgtga gatagcaaat acagtttgtt taatcatatt
     8761 ttttaggatt tcttgaggta tgctatataa atcttcttca tttaattctg gtaatttagg
     8821 aaattctttt gctgcataac ctttaatttt aaatcttgaa tttacacaat ttatgtaaat
     8881 attattttct gaatcagttt ctatctcaac aaaggaatct ggtaattttc taattatatc
     8941 tccaaatagc cttgcatcta caacaacatc acctttttct atgatttctg cttgtacata
     9001 agtttctatt cctatttcag catcatatcc agtaagtttt aattgacctt cttctgtaga
     9061 tataagtata ccttttaata attctattgt tgtttttcca ttaatagctt tttgagcaat
     9121 tccaattcta tttgctagga ttttttgatt acaaattatt ttcaatgtgg ataacctcct
     9181 ctggcttttt atatataaaa ataagttaaa atcatagtag taatagtagt aggtgttgtt
     9241 gataatgtta ataagtatgt ataacattat aaatacaaag atattaacat gtgtataaga
     9301 tgttaatatc tttgttattt tagacttgat aatttgttaa taatttttgt tcaaaaaaag
     9361 tatgaacagg ttattcaaga gatataaaca tacaattgtg tataaattat cccttcaaat
     9421 ctgatataat tttgtctatt ttagtcttaa tttcttcact ttcttctata tccttagata
     9481 ctttgtcatg agcatgaatt actgttgtat ggtctctacc cccaaactct tcacctattt
     9541 taggaaggga taaatcagta agctcgcgcg ttaaatacat agctatctgt cttggataag
     9601 ctattgaacg tgttcttttt ttagaattaa aatcttccat ctttaaattg aatacagaag
     9661 atactttttc ttttattctg agaacattta tttcttcatt tttagaagtt gttataatat
     9721 cttttaaagc ttctgtagca agatcaaaag atattaccct attgctaaga gaagaataag
     9781 caaccactct agttaatgca ccttctagtt cccttatgtt tgacttaata ttttttgcta
     9841 tatatgacat aacctcattt ggcacatcta tacgttctag ttgagccttt tttctaagta
     9901 tagcaattct tgtctcaaag tcaggtgctt gaatatcagt tataagtccc atttcaaatc
     9961 tcgatcttag cctatcttct agtgtaggta tgtcttttgg cggtctatca ctagatataa
    10021 ttatttgttt gtttgcttca tgaagagtat tgaatgtatg gaaaaactct tcttgagttc
    10081 tttcttttcc tgctataaat tgaatatcgt cgattagtaa tacatctacg tttctatatt
    10141 tattcctaaa ttcttcgttt ttatcgtctt ttatagagtt tataagttca ttagtaaatt
    10201 tttctgaaga aacgtaaact acttttgagt cttttttttg actaacaata tgatgaccta
    10261 tagcatgcat taggtgagtc ttacctaatc caactcctcc atacaaaaaa agtgggttat
    10321 aagctttagc tggagattct gcaactgcaa cgcatgcagc atgtgcaaat ctattgctat
    10381 taccaataac gaatgtatca aatgtgtatt ttggatttag attggggtaa agaactctat
    10441 aatttaaatc tgtgctatca gaatttaaat cagcaacctc tttttcgctc aatacaaatt
    10501 taatattata tttttttaat gacagttgac taatagcatc ttcaattaaa tgtaaatatc
    10561 tattctctaa gatatcttta ttaaaatcac taggagccag taagattaaa tcattaagat
    10621 gtatttttaa tggtacgatg tttttaaaaa aggtattaaa acttactgaa gttaagtcac
    10681 cttttattaa ttgtagggtt ttgtcccata aagaaactat atccataata taaacctccg
    10741 aacagaataa ttaatatttt ccacaaagtt attaacagaa aagcaaaaat atatataaat
    10801 tttacagaat aactaaattt atggataatg gtgttgataa attaataata gtataaatta
    10861 ttaaaaaaat atgaaaagat ataaacaata tgtagataaa gttataaata acataaacat
    10921 acaataaatg gtgattataa ctagagtatt gtcagtaatc ttaaaagtta tacacaaaag
    10981 tatccacaag ctgtgaataa tttctaataa gttgataaca tttatgcaca ttatcaacaa
    11041 gtatatttat aatatcaaaa tatatgtcaa acttcaatga tttgtaacta atttatccac
    11101 aatattaact aattgttgat aaaaatataa acatgttaaa attactttat ttgtgtatat
    11161 aattgaaaaa aataatttag aataaaatta aatagatttt tactagtatt ttcaataaaa
    11221 aaaatacata atatatatat ggtagatttt gtgatataag cgtcccaaaa actcgttgac
    11281 aacagtagta aaagtattta taattatatg tgttatgttt actttgaggg taaagttatt
    11341 atttttataa acggaaaata aaatctgaaa ggcggtgcaa aataatgagt aaaagaactt
    11401 atcaaccaaa aaagagacaa agaagtaaag aacatggttt cagaaaaaga atgaagacgt
    11461 ctaacggaag aaacgtgtta aagagaagaa gagctaaagg aagaaataga ttaactcatt
    11521 aattacaaaa gggccgctgc aaaggtggcc tttttgtgta aataattaca attcatagct
    11581 gtgtttatgg aggttaacta tggactttaa taggactaaa gggttgaaaa aagactctga
    11641 ttttagaaaa gtatataaac acggcaaatc ttttgcaaac aaatatttag taatatatat
    11701 acttaaaaat aaatcagatt atagtagagt aggtatttct gtttcaaaaa aagtaggaaa
    11761 agctattact aggaatagag taagaagatt aataaaagaa gcctacagat taaatattga
    11821 tgaaaaaatt aagcctggat atgatatagt atttatagca agggtatcta gtaaggatgc
    11881 tacttttaaa gacatagaca agtctataaa aaatttagtt aaaagaacgg atatttctat
    11941 ttaattgtat gctataaata tggaggttaa tgactttgaa taaaataatt tatatattaa
    12001 aggaaataag taagtattta tcgaatttat gtatttattt agtgagattt tatcaaaagt
    12061 atatatctcc cttaaaggga cctacctgta gattttatcc aacttgctca caatattcaa
    12121 tagaggcgtt taagaaatat ggatttgtaa aaggtatgta tttaacgata agaagacttt
    12181 taaaatgtca tccttttcat ccaggaggtt acgaccctct aaaataaaag agagtaacta
    12241 ttaggaggta taaaaaaatt gaatataata ggaaatttct taggattgat tcttaaggta
    12301 atatttgaat ttgttaatca ttatggtatt tctataatac tttttacgat acttgtaaag
    12361 attattttat taccattaac aattaagcag actaagtcaa caaaggcaat gcaagatata
    12421 caacctcgta taaaagagat acaagaaaaa tataaaaata agccagaaaa acaaaatgaa
    12481 gaaattgtta agttatatgg agaagctaaa attaatccac tatctggttg tttaccttta
    12541 ttaatacagt ttcctatatt aataggatta tttagcgttt tgagagaacc agttgctcat
    12601 ggcgtttttg caaacaaagc tgcattttta gcagctgaca atgggttttt atggataaaa
    12661 agcttaacat caccagatta tgtattagca gtattttcag gagcaagtgc atatgtcatg
    12721 caaaaagtaa tgacaccaaa agatcagtta caaggctcta tgaaagtaat gacatatgta
    12781 atggcaggta tgtctttcta ttggggattt atattcccag caggacttac attgtactgg
    12841 acagtaagta acttattctc aatagctcaa tattacttaa taatgaatcc tttaaaagct
    12901 aaactggctg ctaactctaa ggaggaaaaa gttaatgaga aaaagcctaa aattaataaa
    12961 aagtaagagt aaagaggaag ctataagtaa agttatagca gagttgaatt taaaagcaga
    13021 ggatatagaa gtagaaatac ttgaaaatcc aagtaaaggg tttttaggtt ttataggtgc
    13081 taaagatggt acttatgaaa tttttgttat cgagagggaa gtagatgtag ctaaaaattt
    13141 tatagaggta atgttgaaaa atgcaaatgt tgatgccaaa gtcaatgtat ctcaaaaaga
    13201 taatttaatc atggttgata ttgaaggcaa agaagctgca agtttaattg gtagaagagg
    13261 ggaaacttta gattctattc aatttttgac tggattagct cttaataaaa taaataaaga
    13321 ttctcataca agagtacttg tagatataga aaattataga tcaaaacgag aagaatcttt
    13381 aataagatat gctaataaag ttgctagaga agtagcgaaa acaagaaaaa ctaaaaaatt
    13441 agattatatg aatccatatg agagaagaat aatacattca gctcttcaaa atgacaaata
    13501 tgtaattaca tatagtgaag gaaccgatcc atatagaaga ttagtaattg agtgtaaaag
    13561 ataaagtcaa cctcctaaac attagggggt tttatttttt aatattatta aatcattaat
    13621 gattggttaa atgtaaatct atatgtaaaa aattatgaat taagaggtga taaatttgtt
    13681 tatagatgat acaattgcag caatagctac agcacctgga gaaggtggta taggtatact
    13741 tagaataagt ggagaaaaag ctttgaaggt tgcagaagaa atctttaaat ctatgtctgg
    13801 aaagagtatt gaagaataca ataagagaac attaatatat ggaaatatag tggataatga
    13861 aaatataatt gatgaagttt tattggcata tatgaaagga ccaaattcct atacaggaga
    13921 agatgttata gaaattaatt gccatggtgg atttatttcg gtaaagaaga tattagaatt
    13981 aatactatca aaagatgtta gattagcaga ggctggtgag tttactaaaa gagcattctt
    14041 aaatggaaga atagatttat ctcaagcaga ggctgtaatt gatgttataa aagccaaaac
    14101 tgatatagct catgaagttg ctcaaaatca attagaaggt tctttatcaa agaagataag
    14161 agaattgaga gataaagtca ctgagatatt agctcatgta gaagttgcta tagattatcc
    14221 tgaggaagat attgagcata taacatatca aactcttaaa gaaaaaactg atgaacttaa
    14281 aaaagacatt aaaaaattat atgatacagc tgaaagtgga aaaatactta gagaaggctt
    14341 aaagacggta attgttggga aaccaaatgt aggtaaatct tcactactta attctatttt
    14401 aggagagaat agagcaatag ttactgatat accaggaact actagagatg ttatagaaga
    14461 gtttgtaaac ataaaaggta tacctttaaa aattgttgac acagcaggta taagagatac
    14521 tgatgatatt gttgaaaaaa taggtgttga aaagtctaaa gaatcattta ctagtgcaga
    14581 tttgatagta atggttttag atgcatctag aaagttgtca gaagaagata tagagatatt
    14641 agaaaaactt aaggataaac aaacaatagt gctgttaaat aagaatgatt tgaaacaaga
    14701 gattgaagaa gaaaaaatac ttaaatatgt agaaaataat agtataataa aaatatcagc
    14761 tttacaacaa gaaggaatag aagaattgca agataaaata gagtctatgg tatataaagg
    14821 tagtatcaaa aataattcta gtttagtagt aacaaattca agacataaag atgcacttag
    14881 taaagcatat aaatctgcaa cagatgcttt aattgctttg gaacaaagta tgccatttga
    14941 ctttgtagaa gtcgatttaa aaaatatatg ggactatctt ggatatatta atggtgatac
    15001 agtaacagag gatttactag ataatatatt ccataatttc tgtattggta agtaatgtac
    15061 aaaagtaaac ttgtttttat tatagagatt tttaaaaaat ttgaagtgtt tctcatgaaa
    15121 cattaatttt gaaaagaaag gaattataaa tgataaagtt tgaagcagga aaatatgatg
    15181 ttatagtagt cggagcagga catgctggat gtgaagctgc tttggctact gcaagaatgg
    15241 gatataaaac tttgataata acaatgtctt tggattccat agcattaatg ccttgtaatc
    15301 catcaattgg agggactggt aaaggtcaat tagttaaaga aatagatgcc ttaggcggtc
    15361 agatgggatt aaatatagac aagacatata tacaaagtag aatgttaaat actgccaaag
    15421 gtccagcggt acactcttta agagcacaag cagataaatt taaatatcat gaagaaatga
    15481 aaaagacatt agaagatgaa ccaaatcttg atatagctat ggatgaagtt gtagaaatac
    15541 ttcatgaagg aaatgttgta ataggagttg gaactaaact aggatgttca tttaaatcta
    15601 aagctgtaat attggccact ggagtttatc tgaactcaaa gatatatatg ggtgaagttg
    15661 cattttatga aggtcctaat gcattggggt atgcaaaata tcttacaaat agcttagttg
    15721 agcttggtct tagaatgaga agatttaaga cgggaactcc agcaagagtt catagagata
    15781 gtatagactt ctctgtaatg tctttacaag agggtgatga aaaagtaact ccattctcat
    15841 ttatgaatga aaatatagaa aaaaaacaag aaccttgtta tttaacaaga actacagaag
    15901 aaactcaaaa agttatactg gataatttaa aaaggtctgc tatgtatagt ggagtaatag
    15961 aaagtactgg tccaagatac tgtccttcta tagaagataa agtagtacga tttagtgata
    16021 aaacatcaca tcaattattt atagaaccag aagggttaaa tactaaagaa atgtatatac
    16081 aaggaatttc aactagttta ccttttgaag ttcaattaga tatgtacaaa actataaagg
    16141 gacttgaaaa ttgtaagata atgagacctg catatgctat tgaatatgat tgtgttgacc
    16201 caactcaact aaaaataagt ttggaaataa agggtgttga gaacttattt agtgcagggc
    16261 aatttaatgg aacttctgga tacgaggaag cagcagctca agggcttatg gctggtataa
    16321 atgcagttag aaagatagaa ggaaaagagc catttgtatt agaccgttca gaagcttata
    16381 taggtgtctt attagatgac cttgttacta aaggaactaa cgagccttac agaatgatga
    16441 catcaagagc agaatatcga ctatatttaa gacaagataa tgcagatatg agattaactc
    16501 aaaaaggtta tgatatagga ttagttaaaa aagatagata tgaaaggttt ctaaataaaa
    16561 aggctgctgt agataaagaa tttgaaagac taaaaaatga aagagttaca ccaaaagaag
    16621 taaatagttt gttagaagaa aaaggagcaa caccaataaa ggttggaata tctctatatg
    16681 aatttttaaa gagaccagag gttacttacg aattgcttga agaattaggg aaaggcgctg
    16741 gagatgatgt ttcaagagaa gttaaagaac agtgtgtaat aataactaaa tatgaaggtt
    16801 atatagagaa acaattgaaa caaatagacc aatttaaaaa acttgagaat aaaaagctgg
    16861 atgagaaaat aaattattca tctatagaag gtcttagatt agaggctaga cagaaactag
    16921 atgatataaa acctatttca atagggcaag catctcgtat atctggtgtt tctccagctg
    16981 atatatcagt tttacttata tacctagaac aaatcagaag aactagaggt ggcaaaggtg
    17041 aataatatag aacttctgaa aaacgggatt gaaggtttta atatagatac gaatgacagt
    17101 atgttagaaa aatttaaaat ctatagagag atattagttg actggaataa aaagatgaat
    17161 cttactggaa tagaagatga aaaagaagtg tatataaaac attttttaga ctctatttca
    17221 gctgtaaaga atggatatat aaaaaatggg atgtctataa tagatgttgg tacaggtgct
    17281 ggttttcctg gaataccatt gaaaatatgt ttagatagct tagaacttac tttattagat
    17341 tcgttaaata aaagaataaa ctttttagag gaagttagta gagtactaga gttagataat
    17401 attacattta tacatggaag agctgaagat tttggtaaaa atgaagacta tagggaaaaa
    17461 tatgatgttg ctacggcaag agctgttgct ggattaccga ttcttatgga attttgtgta
    17521 ccatttgtaa aagttggagg gtattttatt tgcttaaaag gtccgaatgc taatttagag
    17581 ctagaagaat cacaaaaggc tattgatgtt ttaggattgg agtatattga aaaaatagat
    17641 gtagagttac cagaggtaga tttaaatcat aatatattag tttttaaaaa agtgatggaa
    17701 acaccagtta agtaccctag aaaagctggt aaaccagcca aaaatcctat taagtaatga
    17761 aaaatttatt attggtaagc ttaattattt ctcaggaaat aattaagctt actgtaaaaa
    17821 aacaaaaata aaggaattat taaagtagat gcagaaataa atttgtatgt acatatagag
    17881 aacaaaaata atttatatct aaaataagag aggtatgtta tggaagataa aagagttatg
    17941 gagataccta tagaagatgt agttccaaat ccatatcaac caagaaaaat attttcacaa
    18001 gtttcattgg aggaattgag caattctata aaggtatatg gtataattca acctataaca
    18061 gttagagcaa aagatggcaa atatgaacta attgcaggag aaagaagatt aagagcagct
    18121 aaattagcag agcttaaaac cataccagca attataaata atatgaacga tgaatcttct
    18181 gctgttctag cgttattaga aaatttgcaa cgagaagact taaatttcat tgaagaagca
    18241 attggttatg aaaacttaat aaaagaacat gcttttactc aacagcaatt agcagaaaaa
    18301 ttgggcaaaa atcaatctac tgtagcaaat aagcttagaa tattaaagct tccaaacgat
    18361 ataaaaatga agctaataga gaataattta acagaaagac atgctagagc atttcttaaa
    18421 ctaccaagtg aagatttaat gcaaagtgtg ttagacaaag tcataaaaaa tgaattgact
    18481 gttaaaaaaa cagaaaaatt gatacaagat gtattagaag aaactaaagt tcaagaagag
    18541 cctgataaaa aacagaatat aaagggtgct atgagtataa gaatttacat aaatactata
    18601 aagcaggcct ttgatgctat atcaaataca ggaattgatg ctaagtataa tgaaatagat
    18661 aagggagatt atatggaagt tgttgtaaaa atccctaaaa aatagagatt actgcttacc
    18721 agtaatcttt ttttgtaata taagccttgt aatataaatt gatttataga cattatttat
    18781 acttaaaaaa cacctattca acatttaaaa ttaatttaat tcttaaaggg gggaacatca
    18841 tgggcaaagt tatagctgta ttcaatcaaa agggtggagt cgggaaaact acaacaaatg
    18901 taaatttaag tgctagctta ggaactttgg gaaagaaaat attagtatta gatttagacc
    18961 cacaaggaaa tacaactagt ggatatggta ttaataaaaa cgaagtagaa aatacaatct
    19021 atgaaattat gttagatggg ttacatatta aagaagcaat aataagtact gaatttgaga
    19081 atgtagatgt agttccatca gctactgaac tatcaggtgc agaaatagag cttacatcta
    19141 aaactaatag agagtatatt ttaaaaaatt ccataaaagc ggtaatagat gaatatgatt
    19201 atatattttt agattgtcca ccctcactgg ggatgcttac aataaattgt ttaactgctg
    19261 tagatagtgt tttaattcca atacaatgtg aatattatgc tttagaaggt gttagtcaat
    19321 taatggagac tatcaaatta gtaaaatcaa gattaaatgc tgatatagaa attcaaggtg
    19381 ttgttttaag tatgtttgat ggaagagcta atttatcaat acaagtagtt gaagaagtta
    19441 agaaatactt taaaggtagt gtatatacaa ctttaattcc aagaaatgta agacttgcag
    19501 aagctccaag tcatggaaaa cctgtaattt attatgataa aagatgtaga gggtctgtag
    19561 cttatttgga gctagcagaa gaatttatag atttagaaga ggaggaatgg tagtatggag
    19621 aataagtcta aaagaagtaa tagattaggt agaggtctta gtgcattgat accagaaatt
    19681 aaaggagaaa cttcagaaaa agaaatagtc aacatagata tagacaaaat atatccaaac
    19741 gaagttcaac ctagaaagca atttgatgaa gaaaagataa aagtattgtc tgattctata
    19801 aaaaattatg gtgttttaca gccaatagtg gttaaaatgg atgaaaataa taaatatatg
    19861 ataatagctg gagaaagaag atttagagca tcaaaacttg caaataaaaa tcaaatacct
    19921 gctataatta aagatataga tatgaaagat ataatggaga tagccttaat tgaaaactta
    19981 cagagggaag atttaaattc aatagaagag gctctagcat ataagagttt aatagagcat
    20041 tacaatgtaa ctcaggaaga aatatcagaa gctgttggga agagtagacc tcatataact
    20101 aatacactaa gacttttaaa tcttggacaa gatgttatag aaatgataga cagtggtaga
    20161 attacagcag gccatggtaa ggctttattg agaattgcag ataaagattt gcaacttcaa
    20221 atagcgaaaa aaatagaaga agaagaactt tctgtaagag aagtcgaaaa tatagctaaa
    20281 aaaatatctg aaaataaaca agaagaacct aaaaaatcta aacctaagga tgtatttatt
    20341 ttagatgttg aagataaact tagaaatata tttggaacaa aggtgaatat ttctaaagga
    20401 aagaaaaaag gtaaaataga gatagaatac tataatgatg atgatttaaa tagtattgta
    20461 tcaatgcttc ttgaatagaa caaaaatata aaacagagag gaagattgtt atgatttatt
    20521 tagataatgc tgcaactaca tatccaaaac cagaaagagt gtataatgct gttttagatt
    20581 gtatgaaaaa ttattgtgca aatccaggta gagcaggcca taaacttgct atgagagctg
    20641 ctagggagat atatgataca agagagaata tagctaagtt gttcaatgta agtaatccta
    20701 tgaatatagt atttacatct aatgcaacag attctttaaa tttagcgata aaaggtgtat
    20761 tacaagaagg agaccatgta ataacaacgt ctatggagca taattcagta ataagaccta
    20821 taaaagcatt ggaaaaaagg ggtattgaaa atactgtagt aaaatgcgat tatgagggat
    20881 ttttagatta tgaagattta gaaaaatcaa taaagaataa tactaaattg attgtaacaa
    20941 cacatgcgtc taatgtatgt ggaactttaa tagatataaa aaaagttgga gaaatagcta
    21001 aaaaacataa tatactattt ttagtagatg catcacaaac agcaggtgtt tatgatatag
    21061 acgtaaatga atgtaatata gatatgttgg caatgccagg tcataaatgc ttatttggac
    21121 ctcaaggaac aggtatatta tatgtaagag aagggttgaa cttaaatata ttaaaagaag
    21181 gtggaacagg tagtaaatca gaagaaatag ttcaaccaga gttattccca gataaatatg
    21241 aatcaggaac tcataatact ccaggtatag caggtcttaa ccaaggtata ctatttatat
    21301 ttgaaagagg aatcaacaat ataagacaac atgaagaaga attatgtcaa tatatgatag
    21361 acaaattaga ggaagtacca gatataaaga tatatggacc aaaggacagt aaaaaaagag
    21421 catcagtaat agctctaaat ataggagata tggattctgg agaggttact ttcttattag
    21481 atagtgatta taatatagcg actagatcag gaatacattg ttcaccacta gcacatacca
    21541 ctttaggtac tttaaaacaa ggtgcagtaa ggtttagtat aggatatttc aacacaaaag
    21601 atgagataga taaagcagtg gaagctttga aaaaaatttc aaaaaataaa tagcatgaga
    21661 tttaataata tagaaataaa aaatggggat gtttcaaaat aaaaatttga atagagtatt
    21721 gaaattttta tgtatattct ttaaataaaa acttcaatac tctattaatt aaattactaa
    21781 ttttgctaat tttcataaaa tctgttaaat tactcataaa gttatatatt ttcaaaggct
    21841 caagtcttgt atgaaattac ttgttttaat tttttatata actatgactt ttgcaatctt
    21901 tttagttgaa aagcgccttc aatcatacta aaataataat attacaatgc taaattattt
    21961 tatcctctat tataattata aatacaaacc ggtgtgactc atcttatgaa aaaagtattg
    22021 ttcagcgttg ataaaactga caattaagta ataaaaatat tatactaatt ttacttttta
    22081 aaaagactta aaattaaaaa aacccttttc ttttgtataa cttacaatat gttctttcat
    22141 tttttgaact gcaaaagaat catattgtga gttgggataa gctaaactaa ttacacggta
    22201 atgctctggt acaaatgggt atgtatcaac attgccaaca caacttttat aaattagttc
    22261 tgataaaata gcaattccaa accctgcttc taccatggca acaatagcac tatcagtatc
    22321 tatgtgaaat tgagagtaca cattaagatg atattcacga agaatttttt ctacttcctg
    22381 gtcataatct tttttaggca taacaaagga catattttgg atatcctcta ttgtaacata
    22441 cccaggatta caaggtacaa atccttttgg aaagacacaa atgatacggt ctttgtgaag
    22501 cggaatagat tcaatatgtg gaggaagtac tgtgttggat ataaaagcta aatccacaat
    22561 agaagtttca atccattcta ggatattaat atagttccct tgaagaatat gtatttcaat
    22621 attaggatgt tcctgccgaa atgatttcat aatctcaggg atccagttta ttgtaatact
    22681 attaaaagtt ccaatacgaa taataccact ttctgaacgt gaaatacgat taatttcttg
    22741 ttctaaaatt tcgttactat gtaataaaat acgaatatga ggtaaaattt tttcagcttc
    22801 tcttgttaaa ctaataccat ttctatttct aataaacaat tgaaaaccta catctatttc
    22861 taattttgca atcgcatgac ttacagctga cggagttaag tttaaaatac ttgctgcttt
    22921 tataaaacta ttttgctcta aaactgtttc aaaaatagta tatccataaa ttgacatatg
    22981 atttactcct ttcctttaga tgagtaaaaa ctcatctaaa acgataaaaa gattcgcttt
    23041 attttataat aataatctac tattattaaa ttataaatac aagtgatcat ttgcattttt
    23101 tactcaagat aataaaaata gtaccaccca aaatacaaga attaaaatat tatttctgtt
    23161 taaaagtgag cggaaacgga acctttgctc atctaatctc atataattac agacaaatat
    23221 caacttgata aaaaggagga actaatatgg taaaatttgc aaaaagaatg gaaaatatga
    23281 aaaattcagc aaatattgtt cgtaatcttt ttaattccat gacagatcct gaaattatat
    23341 cttttggcgg aggtgcacca gcaatagagg ctttgccagt tgacattgta agagaaattt
    23401 ctaatgaagt tttagcaaaa aacaaaagag ggattgaagc cttacagtac agtcacccat
    23461 atggtttaaa agatttacgt gaagcagttg ctcagaaatt attagaacca aagggagtac
    23521 atgcaagtcc agaggacatt atgattgtaa atggtggttt ggaaacaatg aatctgattt
    23581 gtcaggtatt cattgatcca ggagatgtca ttttagtaga atcaccaaca tttgtacatt
    23641 gtgttgaaat ttttgaaatg tttcaggcaa aatgcatagc agtagatatg gatgaacatg
    23701 gaatcattcc agaagatata gaaagaaaga ttcaaaaaca tcacccaaaa atggtttatg
    23761 taattcctac ttttcataat ccaactggca ggacattgac tacagaacga agaaaaatat
    23821 tggcaggtat tggtagtaag tatgatgttt tgattttaga agatgaccct tatcgtgatt
    23881 tgagatatag tggagaggag ttacctccta ttaaagcatt tgatcaaaca ggacatacta
    23941 ttttagcaaa tagtttttct aaaatctttt ctccaggagc aagacttggt tatgttttag
    24001 ctgaacatgc aatcattgaa cgattacttg atgcaaaaac agcaactaat tctcatacat
    24061 cagctatttc tcaagtattg tgtgcagagt ttttcaatcg tggttacttt gatgaacact
    24121 tgaagaatat tcgagatatt tatagagaac gcagagatgt gatgattgaa agcattgata
    24181 agtatttacc aaaaggtact aaaagggtat ttccagatgg tggtttattt acttgggtag
    24241 agctacctga aaatatcaat acaactgaat tattgaaaga agcggtagaa cataaagtag
    24301 cttttgtcgc aggagaagga ttctttacag aaggtggtgg aaaagggcga aattgtatga
    24361 gaattagctt tggcaatgta cctcctgaaa aaattagaat tggtatggaa aggcttggac
    24421 aactaatcgc ttccaaaatg taaataatta cttatataaa atacaacttt atattttaag
    24481 atttataata taaccaaagg aggaatactt atgacaaata aagtaccaaa cttatggaat
    24541 caattggaaa acttaaaaaa atcatataaa tgggtggatt tgagtcgtga agtaagtcct
    24601 gagacacctc attggacagg ctttcctgca atggaagtag aacctttcta cttattggat
    24661 agaggagatg gatttaatgt aaataaatat acactagtaa ctcaatatgg aacacatgta
    24721 gatgcaccaa ttcattttgt tgccgataga aagtatttgg atgaatatac gccaatggat
    24781 atggtacttc cactttgtgt cattgataaa agtgatgagg ttgctaaaaa ttcagattat
    24841 gtagtaactg ttgaagatat tcaagcatgg gaaaaagaat atggtaatat tccagagggt
    24901 gcatttgtgg catttcgttc agattggtca aaaagacctg atgattcttt agataattat
    24961 gattcagatg gtaataagca ttttccagga tggagtatag aagctctgca atatatggtt
    25021 gagaagagaa atattgctgc aattggacat gaaacttgtg atacagatgc accaatttta
    25081 tcaaatgtaa gtggatatca ggcagagaca tatattttag gagaaaatcg atatcaagtt
    25141 gaatttttag taaatttgtc tgagttacct gcgataggag ctattatttt tgtaacattc
    25201 ccaagaatac acaaagcatc tggttttact gcccgttgtt ttgcaatttg cccataaggt
    25261 tttaactgtt agaagggagg gggagacaga tgagtaaaaa agcgatgttt gtttggtgtg
    25321 ttggcttagg tctactagat ggcatctatt gtattctttg ttcctactta ccccatatac
    25381 aaaactatat gtggattggt tttatttctc ttccaattta cttttgtgga ggtgcaaaat
    25441 tagaagagat gccaaaatat ttttgttgtg cagcaagtgg tatattttgg ggtgggctaa
    25501 cattagttgt attagacata ggatttatat ccaatataca tttaaacatg cttgtgttcg
    25561 taacaattgt tgtatgcatt gcttgttttg tacatctagg tgtattgact gaaaatgtat
    25621 ggaaaggatt gttctcaagt tgcccaatga tgtttggtgg atttgcagca attttttctc
    25681 aaggattagc ggagtggttt tgggtacttg taacacttac actagggttg atttttggtt
    25741 gtatcatggc ttcaatttca acacctatca caaaatggat tgataagaat tgaaataaag
    25801 tagctattca ataattttta aaaagttaat ttatttatga aatataatgg tatattattt
    25861 caagatggtt taaaaggaaa agttttttaa tacttttcct tttaatttaa aatataaata
    25921 catttgccac ataagtgctt ctttaaaatc tagtattatc tttactagat ataggagtaa
    25981 gttgttttac caaattagtt ttatatgaag atatttacaa aattttagga ggaaaaaaca
    26041 atgaaaaata ctatacaaac ttttaagaat gctaaaagtg aaggaaaaaa actatctatg
    26101 cttactgctt acgattactc aatggcaaaa ataatggatg agtgtaatat aaatggtctt
    26161 ttaataggag attcattagg aatggttgta aaaggcgaag aaaatactct ctctgttact
    26221 atagatgaaa ttatatatca tacaaaagct gtaaaaaatg gggcaaaaaa tgccttaata
    26281 gtaagtgata tgccttttct atatcttacc atgtttctat agaagatgct gttaaaaatg
    26341 ctggtagact tgttaaagaa ggaggagctc atgctgtaaa attggagggt ggagcaaatg
    26401 ttataaagca aatagaaagc attgtgaatg ctcaaatacc tgtaatgggt catttaggac
    26461 taactcctca atctgtaaat tcatttggtg gatttaaggt tcaagggatt actagtgaag
    26521 cagcaaaaca acttattgaa gatgctaaat taatagaaaa agcgggggca ttttctattg
    26581 ttcttgaagg tgttcctgcg aaaatatctg agataataac taactctatt tcaattccta
    26641 caatagggat aggagcagga attaattgtg atggacaaat tttaatttac caagatatgt
    26701 taggtatatt tgaagatttc gtacctaagt ttgtgaagca atatgcaaat gtaggagata
    26761 taatgaaaga ttcaattaaa aattacatac tagaagttga aacaggggca tttccacaag
    26821 aaaaacatag tttttcaata aaagaatctg aattagaaaa attatacgaa gattaaggat
    26881 gttataagct gtcatatata acaatttatt attatattta gagatggatt gtccatcttt
    26941 tctggataaa aatttatcca gttttatgat tataataacc aattgtaaaa tatatctaaa
    27001 caatatatta tactatgtag atttttcaat gaaataacat cagatattta ctgaatattt
    27061 ttatttctta ttttttagag gaacttcttt taatttaaat ataaaaataa tgaatgtgtt
    27121 tatatagtaa ctgcatatat taatagttta aaaggacact attcattcgt agaaacttaa
    27181 attgatgatt ttattaaaaa atatgtagaa gatattgtag gtttatgtct tcatagaata
    27241 atgattatat tatatgaatg tgatttagca taaaattaga tatattaaag ttgagtgaga
    27301 agaatcttga acaaagttct tcttaccaac tttaatatat ttctattata caatctattt
    27361 tttatcatta ttgaaattgt ttacaacttg atttaactca attaatatac ttccaacttc
    27421 catatagaga attttactat aaacacaagt aatacaatag gaatgtaatt atcacttgat
    27481 ttttttattt tttaaatccc ataacaaaac attaagtgca actattggag ttaacaattg
    27541 ttgtagtata aaagctatta agttatctat atattatctt cctaaaaaag ttttcttaac
    27601 actttaatta ttattcaaaa actatttaaa caaagctata agagagttta agctatcact
    27661 ccaataagat ttattcttta ttttatacat ctaatatttc aaattcgtaa atttacttcc
    27721 aattatagaa ttatacttgt ttcgtattta ttcaatttat cttataaaag cttttgtttt
    27781 gtaaaaatat taattttata ttaaaacaag acttagaaac tatatacttc ttgaaaaaat
    27841 tctaatatag ataaatttaa atattataaa tgaggtattt ttttaaatga ggaagataat
    27901 ggtagataat taaaaatata ttattttatc atttgatata catttattta ttcaaaaact
    27961 ataaaagaac attaactttt ttagaagtag aatttacaac taaagattgt aatattgcta
    28021 ttgaatctaa gcattataaa aaacattgga tacaatttat tggtatagca ttttcaaaat
    28081 gtcaatatca cttgttatat tactgtaaat tgtatagatt atcttagcct tgaaagtatt
    28141 tgtgtatata tggtgactat gataattgac aatctagtaa ataagataaa gataacatta
    28201 gtaggataaa atattggtat ataaaagatc taaatagaac ctgaaaggtg ttgtttcaaa
    28261 attgattttt tataatcaaa tttttatttc tatttttatg tttttgtatg taaaaaagaa
    28321 aggaaggaga taattcaaat ttttattttg aaccatctcc ttctatatga taatttataa
    28381 ttgtttcaag aaattacttt aagtaatctc cttcttcaag aactatatga ccactttcgt
    28441 aattagaacc atcaacagta atttttattt gttcaacatt catatttttt atgtaagtac
    28501 gagcaactga atcaagcatt aaagtttctg catcactacc taagtttgac tttgtaaagt
    28561 cagagctaac atctaatata ccagttttta caccatcaat gtcttttgta gtaaatgaat
    28621 ttaattttgc agattctgga acaactttaa gtttttgaag ttcttcaaat aaagtgttct
    28681 catcaatttt atttaaatca actttatttt caattaaatc tgtcttatct acatcaaaag
    28741 agtaaatagt agctgattga gttttagttt cttcttttgg agtaggttta gctttgttat
    28801 taggaacctc tttttcagta ttgttttctt cttttggttg ctcaacattt gtattgctct
    28861 tagtttcttt tttagatgaa tcacttccat tttgagcatt agtacaacca actgcgaata
    28921 tagatataga taatatactt aacactaaca ttattttctt atttttcata aaaatttctc
    28981 ctctcttaaa aactattctt atatataatt atagtcgtta tgagcaaata tatgaataca
    29041 aaatagtaac aaatttaaaa aatgatttat ttaaattaat aaaactcaaa ataaactaaa
    29101 ttttagtcat ttttatggga aatcatttaa tgtacagtga aaatattgta aaataaaagt
    29161 agtgttttta aaataaatat aagttataat tatattataa aaaaatgtct tcaaaaggtg
    29221 ggaatagtat ggaaattttg agcttaggag aaaagattaa aaaattaaga aaagaaaaaa
    29281 acatgacatt aaaagaatta gctggagata ggataacagc agcacaaata agccatatag
    29341 agagggataa atctcatact agttatgaac tgttggaata tctaggcgat aagctagatg
    29401 taagtgtaga atacttatta gagaccaagg aaatgcaatc aaaaaagata actgataatt
    29461 taatactaca gagcgaaatt tatataaaag aaaatgaatt aaacaaggct gaggaccaaa
    29521 taaaagaagt tttagatata tgtaagagat acgatttaat ggagaactat ggcagatgta
    29581 attttttaat ggctaatatt aatttgaaaa aatctaatta taatgatgct atagaaaact
    29641 ttgaaaaggc attgtacttc tttataaaaa atagtgatag tgaaaatata cttaagtgtt
    29701 atttaaacat agggaaaata tatatgcagg aagactttta taaaggtgct ataagccact
    29761 ttaattttgc agaggaaatt ttgtcagaga ataaatttga ggatgttaac atacacaagg
    29821 aactatatag taagatggca tattgttaca taaaactaga taatccaaat atgtcattga
    29881 agtacataga aaagataaat gaaatagata atagaaatga tagaaaagaa gatgtcgata
    29941 ttttggtgtt aaaagcaaat aatatgcttg agattggaaa atatgaagaa tcaagagatt
    30001 actttaaaaa agcactaaaa atacttgaga gtgaggataa taaaactgga ttagcaaatg
    30061 tgtatttaac aatttgtgat gtttacagaa aaataggtga aacagataga gtacttgaat
    30121 attcacaaaa ggtatatgac ataaagaaaa atgatgaaga tgaatacatg atgtcaggat
    30181 tatttaagat aatagaagca tatatagata aagaagatta tgatttagct agaaaatatt
    30241 gtaagatagc cttagcttca tcaataaaaa ataaaaataa attcaatgaa tataaagcat
    30301 tgagattcta tgctaatatg tataaaaatc agaatgaagt aactcttgca attgaatatc
    30361 tgattaaatg cataaaaata gtatcagatt taggcaacaa tagaatattg gccaatttat
    30421 atatagactt aggtcaatta tattcaaata tatcaaaaga aaaagagtta gaatattatc
    30481 aaaaaggtgt atttatgtac aaaaatttag aaataatgta gggtaaataa acctataagg
    30541 gtatagaaac aatctataac aagcaagata atatctatga taaaatataa attgtatgaa
    30601 tatttttaag gagatgaatc agacaatgag tataaaaata gatgcgagag ggcttgcttg
    30661 tcctaaacca gttataaata caaaaagaga attggataac ctagaagaag gtgttgtagt
    30721 tacaatagtc gataatgaaa cagctaagga gaatatatta aaacttgcta aatctttaag
    30781 ttgtgaagca aatattgttg acgaaaaaga gaattttata tctatagaaa ttagaaaagg
    30841 taaaaatata ctagataaac aaaatgttgt agataataaa gaaagtgaat tagacaatac
    30901 atgtatattt atatcttcag ataagatggg acttggaaat gacgaattag gaaaagtgtt
    30961 aataaaagga tttatatata cattaacaga atctaaacct tatcctaagt atgtactttt
    31021 agttaatgga ggagtaaaat taagtgctga aaatgaagaa accatagaaa atctaaaaat
    31081 acttgagaat atgggtgtag aagttttatc ttgtggtact tgtttagatt attataattt
    31141 aaaagacaaa ttacaagtag gtacagttac aaatatgtat actatagttg agacattaaa
    31201 gaatgcatca aataccattt ctatataatg tatgtttgtt taataatata aaattaataa
    31261 taaagattaa ctcaaataga tagtcagaaa ggattaagta atgaatcaaa tgtatatagt
    31321 gtcatttaat tcgacacatc atgcgataag atcagaaaag ttatttggtg aaaatagtct
    31381 aaaagtaatg gctcttccaa caccaagaga aataacagca agttgtggaa tatcaattaa
    31441 attttctttt gaagatatgg aaaagataaa aactatttta gttgaaaata atgtagatat
    31501 aaaaggaatt tattgtataa gtaaattaga aaatggctca aaagaagtag agaagttaga
    31561 ttaggaggct aattatttat gccaatggat ttaaaaatag gtgatattgt tgaattaaaa
    31621 aagcaacatg catgtgggtg taaagagttt gaaatcataa gaacgggaat ggatataaag
    31681 ataaaatgta ctaaatgttc aaggctaata atgcttgata gagagacctt agaaaagaga
    31741 gtaaaaaagc taataaaaaa gtgataaaaa tttaacactt aaaaaatgtc aaataccgta
    31801 tattaatatc caaaattttg gtataataag aattgaagaa aacattttca tgggggtgct
    31861 ttaattatgg cagttaaata tgcaaaaaga atgcaaggat tacaaggatc agaaatacgt
    31921 gagcttttaa aacttactca acaaccacaa ataatatctt ttgctggtgg aatgccggct
    31981 ccagagttat ttccagttga ggaaatgaaa aaagtatcag ttgcagtgct tgaagaaaat
    32041 ggaagatcag ctatgcaata tactacaaca gaaggatatg aaccattaag agaaaaaata
    32101 gcagctagaa tgaatgataa aaacaaaact aatgtaaaca aagatgatat attagttaca
    32161 agtggttctc aacaaggtct agattttgca ggaaaagtat ttattgatga gggtgatgta
    32221 attttatgtg aaagtccatc ttacatagga gctataaacg catttaaatc ttatcaacct
    32281 aaattcatag atgttccaac agattctgat ggaatgataa tggaagaatt agaaaagata
    32341 ctagaaacaa ctgatagaat aaaaatgatt tatgtaatac ctgacttcca aaatccaaca
    32401 ggaagaactt ggccacttga aagacgtaaa aaattcatgg aaatagtaaa taaatttgaa
    32461 ataccagtaa tagaagataa tccatatgga gatttaagat ttgaaggaga gactttacca
    32521 tctttaaaat caatggatac aaaaggatta gtaatattct taggaacttt ctctaaaata
    32581 ttctgcccag gatacagatt aggatggact tgtgcttctc cagaaatttt atctaagttt
    32641 aactttgcaa aacaaggtgc agacttacaa gcatcaacta tatctcaaat ggaagtaagc
    32701 aaatttatgg atatgtatga cctagatgca catgttgaca aaataaaagc agtttatgtt
    32761 aaacgtagag atgtaatgct taagactatg gaagaagagt tcccagaagg attagtattt
    32821 actcatccag aaggtggatt atttacatgg gtagagcttc caagtaattt aaatgctaaa
    32881 gaattaatgc caaaatgttt agataagaat gttgcttatg ttgctggagg aggattcttc
    32941 cctaatggtg gtagagaaaa tactttcaga cttaactatt caaatatgcc agaagaaaaa
    33001 ataatagaag gtataaaaaa tatagcagct gtattaaaag aagctatggg tgtagaagct
    33061 taattaaaaa taataactta tatataatac aagggatggt tgttgccatc ccttgtttgt
    33121 ttgaaaagta tataattcac cttatactaa actttgtcca aaatttaaat tgacagaaat
    33181 aagaataaat gataaaatgt gtaggtatga gattttagtc tcatttctct gctctaagag
    33241 tgtagagccg ttaagtccaa agggaggtga attatagtga gaaattatga attagtttat
    33301 gtggtaaagc caaactctga tgaagaagta agagaggcta tactaaacaa agttaaggaa
    33361 gttgttgcaa ctgacggaga aatagttaaa gttgatactt ggggaactaa aaaattagct
    33421 tatccaatag ctaagtttac agaaggtttc tatgtattag ttaacttcaa atcagcagta
    33481 gacgttccta aagagataga cagaaactta aagataaatg aaaacgtaat aagacacatg
    33541 atagttgttg cttaataact ggttttatta taaaaaatag gtggtgtttt tatgaatcaa
    33601 gttgtattag tgggaaggtt gactagagac cctgaattaa gatacatccc aggtacagga
    33661 acaccagtgg catcctttac aatagccatt gatagagact atgtaaaaaa agatggatct
    33721 aaagaaactg attttatacc tgttgaagta atgggtaaat ctgctgaatt ttgtgctaac
    33781 tacataacta aaggtagatt agtagcactt caaggatcta taagagtaga caattatcag
    33841 acacaatcag gtgaaaagag aacttttaca aaagtaagta ctagatcagt acaagctttg
    33901 gatagtaaga ataaatcgga aaattcatat agagagagtg ctccagcttt tgagccaagc
    33961 tttgaacctc aaggtttaga cccacaaggt ttccaagcta tagatgatga cgatatacca
    34021 ttttaaaaag gagggaaaaa agtcatgatg aataaaaaaa gacgtaagaa aaaaagagtt
    34081 tgtcaatttt gtgctgacaa aaacgctaaa atagattaca aaagtactca aagattacaa
    34141 aagtatataa ctgaaagagg aaagatatta ccaagaagaa tatctggaac ttgtgctaag
    34201 catcaaagag aattaacagt tgctataaaa agagcgagaa atatagcact tttaccatat
    34261 acattagact aaaaaaatga gccttgtgct cattttttat tatatgtatt tatatatcta
    34321 aatgaggcga gctataaagc tcgttttttt gtttatatac ttaaatatat tattatttat
    34381 gatataatat tatatattaa ggagggttgt aaacgtgaaa atagataaag gttctgagat
    34441 aacgagaaac ataaagataa tagaatggat gaaaacagaa atattaatga gtgtaagtga
    34501 tttgtttaat ttattgttta aaggggtaaa accattagat gaagcaattc aagatacttt
    34561 agcaaatata ataatgataa catatctctt agcaaagaga ttaggaatta gttttagaga
    34621 tgtggattat aaagtcaagg aaaaaataaa aattggtata gatgaggacc atagcgttga
    34681 aagatggtat ggagatttat ctaatttaaa aaaacatatg gataataggg agtgatatta
    34741 aattgaataa taaaattaga ctatctaagg caatgtctat aatagtttta gctataataa
    34801 tcgctttagt aatagcctat attccaatgc taggaatatt tagtatgtta gcagctgttc
    34861 catatgtaat tataggtgct attactgata gaaagtattc tcttatatct attttggtta
    34921 cattttgtgt actgattcta tttgcagaca tttcttatgc attaaatata tgtataatgt
    34981 attctttacc aggtatagta ataggaaaga tgctaaagag aagctttgaa caagaggaca
    35041 gtaataaatt cgaaccgata tatggtggaa ccataatatt tgtactttca atgcttgtat
    35101 atttttttgt attaaagaca tttttaaatg tgaatctatt agatgaagtt tctaagatga
    35161 tatcagaaat tgtaaatatt caaaaaaata gtttttctgc aactgaactt aaagtgtttg
    35221 ataaaatgaa gccagatgag attgtaagtt attttacaaa tatgctacca atgatgttat
    35281 ttttacaagg gttgttatca gcgtttgtca catattattt gagtgtattt tttataaaaa
    35341 ggattacaaa gatgaatata agatttccta agtttgctga tttttattta ccgggaaatg
    35401 ctatactcac aactttctta ctttatttat tagtcttatt tattcaaatt attggttcaa
    35461 aattatatac agaattaata atgactaatt tacagctagt ttttaattta atgtttgtaa
    35521 ttcaaggtat agcagtttgc atttatttct taaagaaatg gataagacag ggaccaaata
    35581 aaattatgtt tttttcaggg ataattttat atttatttgg atttatggga atatcttttg
    35641 ttggtatggt agatagtata attgacttta gaaaggtaag aagctataaa tccacttagg
    35701 aggatagaaa tgagtaataa acaaaccttt aaattaaata tgccagaaat aaatttatat
    35761 ataattgtta ttggtatttc tagtataatt ttgctttatt acaacttgta tgtagggtgt
    35821 ttatttttct gtatttttgt atatatggtt tttcacaatt ggagaactac taatattaga
    35881 cgtcatgaat ggacagagta tattcaaaat ttatctttag atatagatga aacaactaaa
    35941 aaagccataa taaatcttcc aataccatta tgtattttag aatttgatgg aaatatatcc
    36001 tggtataatg gaaagtttta tgatatgatt ggtcaaaaag atttacttga taaaaatata
    36061 gaggatatag ttaaaaatct taatttaaga aaagtattaa atgaaaataa agagatgtac
    36121 acagaaataa actataaaga aaaagaatat acaataattt ataatgttat aaaaaatgat
    36181 caagaaaaaa atcctaaata tttgatgata ttatactgga tagacaagac tgaatattta
    36241 aaagtaaaac aaaattatga tgatgaaaaa aatgcaatga tgctaataca agtagatgga
    36301 tatgatgaag tattaaaaag tgcagcagaa gataagagag ctttaattaa tgttgaagta
    36361 gagaaaatac tttctgcttt agaattaaat tcaaatggtg cattgagaag aacttcaaaa
    36421 gacaaattct tcttggtaat gcataaaaaa gagttaaaaa aattggaagc tgagaagttt
    36481 tctattttag atacaataag acatattgat tatggaaata atcttcctgt tactataagt
    36541 ataggaattg gtatagatgg agatacatta aatgagaacc taaaacttgc tacgggtgct
    36601 ctcgatttag cacttggtag aggtggtgac caggctgttg taaaaacaaa agataaattt
    36661 gtgttttatg gaggaaaatc taaagctgta gaaaagaaaa ccaaagtaaa atccagatta
    36721 ataggtcatg ctttaagaga ggttatacaa caaagtgacc aagtttatat aatgggacat
    36781 aaatatcctg atatggatgc tatgggagca gcagttggtg tttatgatat atgtaaatcc
    36841 tgtaacaaaa ctgcaaacat agttttacaa tctgtaaatg aatctataga aatatttata
    36901 aataaaataa atgaaaataa ttactataaa aagttgttta ttggaaaaga ggaagctatt
    36961 gacaactgca ctaaaaatac attagttgta gtagttgata ctcatagacc aaattatact
    37021 gaatgtgaag aactgttaaa gctatcagag aaggtagtag ttatagacca tcatagaaga
    37081 ggtgtagagt ttataaatga tgcagtgctt ttattccatg agatatatgt atcctcaacg
    37141 tgtgaaatgg ttacagagtt agttcagtat atggatgaag atgtaacaat aaataaactt
    37201 acagctgaag ggcttttagc aggtataagt ctagatacta aaaactttgc attcaaaaca
    37261 ggtgttagaa cttttgaagc tgcttcttac cttagaaaag ttggagcaga tactatagag
    37321 gtaaagaaat tcttcaattc tgatgtaaaa gatttcataa taaaagctga aataattcaa
    37381 agtactaaaa taattaataa tagaatatgt ttagcatatt caagtactga gatagatagt
    37441 ataaatgtta taatagctca aactgctgat gagttattaa atatcaaaga agtagaagct
    37501 tcctttgtat taggtgaaaa agatgatact atatttataa gtgcgaggtc tttaggacaa
    37561 ataaatgtac atgtacttat ggaaaaatta ggaggcgggg gacacataga tatagctgga
    37621 gcacagttaa aaaatgtttc tctaaaagaa gcttataaga tggtaaataa aataatagag
    37681 gagtatttgg aggaggaaga atagatgaaa gttatattat taaaagacgt aaaaggaact
    37741 ggtaaaaagg gagaaatgaa agaagtaagt gatggatatg caagaaattt cttatttcct
    37801 aaaaagatgg ctgtgcaagc agatagtgta gcaataaaag aattaaatga aaagaataaa
    37861 tctaaagaaa taaaagcaca aaaagagtat gaagaagcag ttttattagg taagcaaatg
    37921 gaagaaatta atatagaaat atattcaaaa gcaggagaag gtggaagatt atttggttca
    37981 ataacttcta aagaaattgc tgagcaatta aagaaacaaa aagacataga tgtagataaa
    38041 agaaaaatat tattagatga accaataaga tctttaggtt caactttcgt agaaataaaa
    38101 atacatcaaa aagtaactac taaaataaga gtggatgtaa aagaaaaaca gtaataacta
    38161 gaggtgatta agatggaaga tatgacgaga attcctcctc atagtgtaga atcagaacaa
    38221 tcaatattgg gttctatact tctagataaa gatgctataa taacggttac agaaactata
    38281 aagcctgatg atttctataa agaggctcac aaaataatat atgaatgtat gataacttta
    38341 agtaataaag gtgagcctat agacttgata acattaacag aagaactaag aaaacaaggg
    38401 catcttaatg atattggagg aatcagttat attacaagtc tttctactat agtaccgacg
    38461 acttcaaatg taaaatacta tgctgatata gtaaaagaaa agtctgtact tagaaagctt
    38521 ataaaagctt ctaatgaaat aataaatcta ggatatagtg gagcaactaa gattgaagat
    38581 gttttagaac aagctgaaaa gagtatattt gatatatcac aggagaaaac tagtgatgat
    38641 tttaaatcta taaacttagt tttgatggat gcctatgata tgatagaaaa attatacact
    38701 aacaagagtg atgtcactgg tataactact ggttttaaag atttaaacaa aaaaataaat
    38761 ggtcttcaaa ggactgattt aatattaatt gcagctagac cagcaatggg taaaactgcc
    38821 ttttctttaa acttggttca aaatgcagcc ttaaaaggtg atgcctctgt agctgtattt
    38881 agtttagaga tgtctaagga acaattagta caacgtatgt tatcttcaca atctagtgta
    38941 gaattaaaaa aaataaagac tggaacactt aatgataatg attggcctag aattatagat
    39001 gctatggcag tattatcaga tgccaaaata cacatagatg atactcctgg tataaaaata
    39061 tcagaactaa ggtcaaagtg tagaaagtta aaaatagaaa aaggactaga tttagtgctt
    39121 attgattatc ttcaacttat ggaaggtgaa ggtaataatg aaagcagaca acaagagata
    39181 tctaagatat caaggtcact aaaaatatta gcaaaagaat taaactgtcc tgtagtagca
    39241 ctatctcagt tatcacgtgc accagaacaa agagcagacc atagacctat gttatctgat
    39301 ttaagagagt ctggagcaat agaacaggat gcagatatag ttatgttctt atacagggac
    39361 gaatattatc atgctgattc tgagagtaaa aatataggag aagtaataat agcaaaaaat
    39421 agacacggtg aaactggttc tgtggaactt gtttggcttg gtgaagttca aagatttggg
    39481 gataagttga gagacctata atctaacgaa tatccacaga acgtcctttc tttctacagg
    39541 aaaaatgtgg atacatgtca ctaaatatgt ccaaacattg aaatttagct aaaaaactat
    39601 ccacactatc cacagatggc ctgttgataa gtgtgaataa gtagataaag caagcttttg
    39661 gcttgcttta tctgtgtata aatattaatt attaggagga ataatatgga aaaaataagc
    39721 ttaaaatata tatatcccaa tataattaaa gtacttgatg aaataaactt atttagagta
    39781 attgacaata atttaagaga atctattgtt gtttatgcta ataatgtgga taatcagtat
    39841 catataaaca tgactaatac aaactttgga aatataatta acatatgtaa attagaaaaa
    39901 cttttagatg tggataaatt tatggaaaaa gttataaaat atgaaaaaga aataatagag
    39961 aaagaagagt tttcaaaaat agaagaatat atgttaaata ttggagaata ctaaaaaagt
    40021 tgaaaaaaat acgaatgttt gatagaataa gtaagtaaag tgttcgagag tatataaaat
    40081 atagaggtga attacatgaa aacagttgca attgttggtt ctcaatgggg agatgaaggt
    40141 aaaggtaaag ttatagatta tcttgctact caagcagatg tagtagtaag agggcaaggt
    40201 ggaaataatg caggacatac attagttgta gaaggtaaaa aatacgcatt acatctaatt
    40261 ccatctggag ttttaaatcc aaatacagtg aatataatcg gaaatggaat agtgtttgac
    40321 cctaaaggat ttttagaaga attggaaatg tttaaaacgg ataatataag tacagaaaat
    40381 ataaaaataa gtgatagagc acatgtcata ttcccatatc ataaagaact agatgcattg
    40441 tcagaagaag ccagaggcga tttaaagata ggtacaacaa aaaaaggtat tggaccttgt
    40501 tatatggata aaacagagag atctggtatt agaatatgtg acttaatgga taaagataaa
    40561 tttgctataa aattaaaagc tcaaatagat gctaaaaatg aaatagttaa aaatatatat
    40621 ggaaaagaag aattatttga ttttgaaact atatataacg aatatctagg atatgcagag
    40681 caaataagaa aatatgtggc agatacgtct gttattgtat atgatgcagt aagagcaggt
    40741 aaaaaagtat tgtttgaagg agcacaaggg actttattag atttagattt aggaacttat
    40801 ccatttgtta catcttctca tccaacatct ggtggatttg caattggtgc aggtataggg
    40861 ccaaatatga taaaagacgt tgttggtata gtaaaagcat atactacaag agttggagaa
    40921 ggaccgtttg ttacagagca aataaatgaa actggagata agataagaga acaaggacat
    40981 gaatttgggg taactactgg tagaccaaga agatgtgggt ggtttgatgc agttatagtt
    41041 aagtatgcag ctagagttaa tggattgact agtatttcat ttatgttact tgatgtatta
    41101 actggatttg ataagataaa agtttgtacg tcttataaaa tgggcgataa gataataacg
    41161 gatttcccag cttcattaga tgatttagca aaatgtgaac ctgtatatga agaattagat
    41221 ggatggaatg aagatataac tcaaatagat aactttgatg accttccaga aaatgcaaag
    41281 aaatatgtag caaaaataga agaactagtt ggagtaagtg tagatatggt ttctgttggt
    41341 ccaaatagag ctcaaactat aataagaaga aatatatttg cttaatattt tatcaattaa
    41401 ataatttaaa atagttgaag aagagtatct caagataatg tttatagtta ttagagatgc
    41461 tcttttatat ttgacttaca ttgatttttt attaagttaa agctacttat acatattcta
    41521 actgaaatta aagttgaatt tatgtagata catataggtt ttttaaaaag aattttgttg
    41581 aaaataaatg gctaaagatg attttaatta tattctaaaa aaagtaaaaa aaactattga
    41641 ctaaaaatta tatagacgct ataatataac ttgtgagtga aagaaacgac gaaaaaagtc
    41701 gaaaaaatgt ggtctattag ctcagtcggt agagcacctg acttttaatc agggtgtccc
    41761 gcgttcgagt cgcggataga tcaccaaaat atggctcgtt ggtcaagagg ttaagacacc
    41821 gccctttcac ggcggtaaca ggggttcaat tcccctacga gtcaccagta tgggactata
    41881 gctcagctgg gagagcacct gccttacaag cagggggtca caggttcgag ccctgttagt
    41941 cccaccaaat tttgaattag agataaatac tagattatat gctggtgtgg ctcaacggta
    42001 gagcagctga cttgtaatca gcaggttgta ggttcgattc ctatcaccag ctccacaaag
    42061 tacataaatt caaattaata taattttcta tgttacagga tacttttaag tatctttttt
    42121 taatttcatt tttattgtat taaaaatgaa attaaacata caacaaaatt ttgaattact
    42181 tgcaatgtga tagttttaaa tataaaattt agaatcattc tagcataata ttatgtaata
    42241 tagcaaattt aatttatagt atcaataaat atagactact aagaatgtaa atgatttgtt
    42301 agattaaggt acattagata tgtaaataga aaaataaaaa gtatgtttta atttatgtga
    42361 tataagtttt aaacagagaa gcaagtttgc tcttacctct ctatttaaaa ataaaaaaat
    42421 gttttttaag ggctatttta tttaaatctt tcccatctca aatcatctcc agtaaattct
    42481 aaaatcctaa acttatctaa tattctagag agagttcttt gagtgtaagt atttcctatt
    42541 tgagatggtg ttaagttggt tgaaataatg atttttttac cagcaacaag tcttgtattt
    42601 acaatattga agatttctcc actagtaaaa gaattattaa gttcagttcc aaggtcatct
    42661 attattaata aatcacaatc aaacaagttt ttataattat cttcacttat ttgattattt
    42721 gtgtctcttc taaatttata atcttcaaga atatctaaaa ttctaaaaga agtttgatag
    42781 attacaacat tgcctttatc taacaattcc tttgcaatac aattgcacat ataggtcttt
    42841 cctagtccag tagaaccata aaacagtaga ttttcactat tatccttctt aaaatcatga
    42901 acaaaatttt cgcagatact taaattattt agcatatttt ctctaggaga tatttcacca
    42961 tcagagcctt tcttaggaga aaatatattc aagttaaaat tcgaaaaatt ttcctgactt
    43021 aaaatcctat ctaaattaga cattttataa gcttcattta caatttcttg tttgaggcaa
    43081 gaacattttt ctccattagg taaaaatcct ttatctttac aagaaataca ttgaaacttt
    43141 atttccaagt aatcaagagg tatgttactt tcagctaaaa gtctttcttt ctttactttt
    43201 aaagattcta tattctcttt agtcttcttt acaatttcat ctttagactt aggatttaaa
    43261 agtactatct tagctaaact gagacctatt ttagaaattt catcatctat agattttatc
    43321 tcagggattc tattatatac ctcatttttt ctatgttcta ataagagttc attatcatct
    43381 cttctcttag catatttagc aagtattttt cttattttat cctcattcat ttaatcacct
    43441 acttaaactt ttctttttga ctttttttaa taatctcatc gagctcatca gaggtatact
    43501 gagtgaatgt ttcgttgaaa ttatgaaact tagttttttt gtaagtattg ttgttttgag
    43561 tagtattaat ctgcttctta ttaatattct ccttaactat acgttcttcc tctttttgct
    43621 ttaaatcatt taaatttttt atattttttt cattccaatt tttaattata ccatttatat
    43681 aagatatact tgggtttgaa atattcttag acttagaaca tgcatttatt atcaaatcta
    43741 tatccatatt aaatttatca aaccaggtgt ccataagttc tttttctgat tttgatggtt
    43801 gtcttgaaaa tcccaattca ttgaaaatcg ttttatataa aatatatcgt tcacttctta
    43861 ccaaaaagct ttcttcaaca tcttttggcg tatataaatt tgaatcatac caatttctaa
    43921 taatgccttc aatgtattta actggctttg atgtaccagt tttatctttg acgtattcat
    43981 atgcgcaaag tatcatatcg gggctcatat tgtatttatt cattatatcc ataatactca
    44041 tcttttcact tgggtcgaga tatcgcccaa ctattttatt tatagaatta aacatttttc
    44101 taatacttgg attttcagaa gtagatacaa ctttatctgt attagatttt atagatgaat
    44161 tattgcttaa tatattctca atatagaaat tttttaaatc taaaaattct attgaataat
    44221 taaaattatc atattcttca ttgtcatgta tttttataat cttcttttct tcccagaatt
    44281 tccaagcaga taacacatca gacaatggta tatttaggtt tttggctatt gaattattgt
    44341 cgaacttagg attagaagta atatcacatg cttgtctata tcctaaaaga taaactttta
    44401 cgtataaccc gtccgccatt ggcataaata tatctataaa gatattggga atagtgattt
    44461 cacctaaatc tatttcattg ctttctttaa aaaacatttt atcacctcag attaaattat
    44521 atcatttttt atattatatt tgtctgtaaa caaataaaag gtcacaagat tagcatgtaa
    44581 atattttcta aaagtattca ttttgaaaag gaggagatat tttggttata aaattcaacc
    44641 aaaaagtaag aagaacatta tcagtagcga ttctatttat ggtattaata ataggttgct
    44701 ttatagaaaa ggatgacagt ttagaaacat acaaagaaaa aactaattca aaaataaatc
    44761 agtataatat ggatgttata tttgatgatg agactaagag gttaatgtgc aatcagaatg
    44821 ttgactacat aaataataca aaatcaaaca tagataaaat atatttccat atatatccga
    44881 atgctttttc caagaaagat tttgctcctt ttgaaaaaag tgaaatgaca agggcttatc
    44941 ctaatggatt taacgaagga tatatagata taaagaatat attaaataat aatagtaaaa
    45001 tggagtataa aattaaagga gacaaaaatg acatattaga aatagaatta gggaaagagt
    45061 taaaaccaaa tgaaagaatg tcattagata taaaatataa cgtaaaaata ccaaattcaa
    45121 ttggaagatt tggatatgga gaaaatacta taaatgttac taattggttt cctatagctt
    45181 gtgtaaatga tgaaagggga tggaatttaa agagttatga aactattggc gacccatttt
    45241 atagtgagac tagcgatttt catgtgaaac tattgattcc aaataaatat aaaattgctc
    45301 atacaggaaa acttattgat gataaacatg ataataagaa aatgctatat gaaatagaag
    45361 ctgaaaacgt tagagatttt gcatttatac taagtagtaa atttgatgta aacaaagtag
    45421 attcaaaggg agtagctatc aatacatata atttaaataa aaagctttct aaaaaagcaa
    45481 ctgaagtggc aaaagattca ataaatatat ttagtgaatt atttggaaag tatccttaca
    45541 aagaattttc tgttgtagca agtgactttt ttataggggg gatggaatac cctatgcttg
    45601 ttatgataga ccaaagttta tataatgaaa aaaatgaatt tttactagaa tatgttattg
    45661 cccatgagac agcacatcaa tggtggtatt ctgctgttgg aaatgatgaa ataagtgaac
    45721 cctggttaga tgaagcactt actgaatatt ctacaatagt ttattttgaa caaaagtatg
    45781 gtaaagatat ggcaaacaag cttataaaaa ctatggagat acagacaaaa agttatttga
    45841 gtgaaaatat atttaagcca gcaaatgagt ataaaaattc tactgaatac agcttgaatg
    45901 tttatacaaa aggcgcaata gcatttaatg aaataagaaa agaagttgga gataaagtat
    45961 tctttgagac tttaaatgag tactataata aatataagca taaaaatgct aatggaagag
    46021 cttttgtgga actatggaat agtaaaggtg tagatataaa taagattata agtgaatgta
    46081 agtaaatagt gaatgtaagt aaattttgtg cagagtatta aattttattt aatactctgt
    46141 ttttttggta taatataatt tataaggcag aaaaagaggt gaaggaatgc taaagtattg
    46201 ttcagtaggg agtggtagta gtggtaattg ccactatata gggtataaaa atactaatat
    46261 actagtagat gcaggattaa gtggcaagag aataactaca ggtcttaaag acattggtgt
    46321 agatgcagat aaattaaaag gaatatttat aacacatgag catgttgacc atataaaagg
    46381 agcaggtata ttatcaagaa agtttgatat accagtattt gctaatataa aaacatggtg
    46441 ttctatgaag gacaaattag gtgacatcaa agataaaaat atgaaagtat ttgaaaatga
    46501 taaaacctac tcattaggtg atatcatagt aagacctttt tcaatagaac atgatgcgtc
    46561 tgacccagtt ggatataatt tttatacaga gagtgatgaa aaaatgtcta tagctactga
    46621 tataggatgt ataactcaaa atataaaaaa acatctatat aaatctaaat tagtagtatt
    46681 ggaatcaaat tatgacccta atatgcttat gatgggttca tatacatatg ctttaaagaa
    46741 aagagtaatg tcaagtactg gtcatttatc caatgaagat gcagctaatt tctgcgttga
    46801 acttattaat gaaggtacag aatctatatt attagcacat ttaagcaaag aaaataattt
    46861 tcctgagtta gcgtatgaga cttcaaaagg agtattagca tcaaatgata tagtagttgg
    46921 acaagatgta aaactagatg tactatcacg aaatgatgtt tctaatgttt atgagatgaa
    46981 gtagaggtga ataactttgc taaagagaaa ttttgaaaat gttgaggata ataaaatttt
    47041 atactctata aagcagggta tgattttagc gatacctgct attatgactg gttcaactgc
    47101 tcttgtaatt ttgaatcttc caataaaggc ttatcaagaa tatttatcag gcttgtttaa
    47161 tggagaggtt acaaatattc ttaactttat aaatgattct actttaggaa ttatttcatt
    47221 aataatatta ttaacaataa gctatagtta tggaaaaata tatgggagca agtatacagt
    47281 acttgttcct atagttgcaa tgtgctcttt tttagtattt tcacatggta atgagcttaa
    47341 ttcttatata gaaatattta aaacaaagtg gttatttaca tctataattg tttctatgac
    47401 atcttctgta ttgtttgtaa aacttacaga atcttttgtt acaagtgtaa agtttcatac
    47461 agaaggggct gatgcagact ttaatatggt agtttcggct atagttcctt tcataatagt
    47521 agtatttttg ttttctattt ttagagtggt aatgataagt ctaattggca gttcaaactt
    47581 tcaagatata ttttataatt tattttcaaa tgtttttaat aaaatgggaa caaaccttat
    47641 gagtgctctg ttgtttattt ttttaatgca ctttatgtgg ttttttggga ttcatggtag
    47701 taatgtatta gataccgtcg caaaaaattt atttgaaaat agtatggcaa ttaacataaa
    47761 tttagttaat aataatcaat taccaacaga aatttttact aagacctttt ttgatacaat
    47821 ggttttattg ggaggatgtg gctctttact atgtttagta attgcaattt ttcttagtga
    47881 aaaacgtata aatgtaagaa agttagctaa aattgcttca ataccagctc tttttaatat
    47941 caatgagatg ctagttttcg ggataccaat tgtttttaac tatattatgt ttgtaccttt
    48001 tgtaattact cctataatct taaccgttac aagttatgtg gctatgtcta caggtattgt
    48061 accatgtaca gtttcagctg tagaatggac ctcacctata tttttaagtg gatatatgtc
    48121 tacaggttca ataagaggta gtttgttgca agtatttaat ttatgtgttg gtgttatgat
    48181 ttatattccg tttataaaaa tgtcgcaaaa tagatataca tatatgttta aaaataatat
    48241 agaaaattta acaaacttat taaaaaggta tgaattaaca ggtgaacagc ctaatcttct
    48301 aaaccataat ggtaaaatag gttcaatttc aaaaatgttg gcatcagact tgaagtttgc
    48361 tatgaaaaga ggagaaatag agctttttta tcaaccacaa gtcaattata atggaaatgt
    48421 tgtgggagca gagggattac ttagatggaa acattcaata ggagggttca tttatccacc
    48481 actagttata attttggcta aagaagaagg gttcttagat gagcttggag agtatattat
    48541 taataaagca tgtattgatt taaagaagag tgaaaagcta ttgagaaatc ctgttaagtt
    48601 ctctgtaaat atatctccag accaacttga tgaccctaag ttaccagagc aaataaaaaa
    48661 tatcattagt agtaatgata taaatcctaa tatgttaggt atagaaataa cagagcaaat
    48721 tgcattatca ggttcacaaa taattattga acgtatcaat gcgatacata acttgggaat
    48781 aaagttaatt atggatgatt ttgggatggg gcatagctct cttatatatc ttcaaaataa
    48841 taactttgat atagttaaat tggatggttc attagttaaa gagatactta caaataaaag
    48901 aagtagtgaa attataatga ctattgtaaa tctttcaaaa aatttagatt ttgatatagt
    48961 tgttgagtat gttgaaaata tagaccaaag ggataagtta tatggtttag gatgtgaaat
    49021 atatcaagga tattattata gcaaagcaat accttttgaa gagtttgtag aatatgcaaa
    49081 tcaagaaaga gagatataat tttataagag cttgtaaatt ctagtaatgc atagatttgt
    49141 aataaaatta agtttaggag aaatatatga atataagtat agtagtagta ggtaaaatta
    49201 aagaaaaata tttaaaatta ggtattgatg agtttaagaa aaggctttct aagtattgta
    49261 agttagaaat tatagagttg gatgatgaaa aagctccaga gaatttgagt gttaaggaaa
    49321 tggaaattat aaaagacaaa gaaggaaaga aaattttagg gaagataaag cataatagtt
    49381 atgttatagc cttggctatt gatggtaagg gtttatcctc tgaagagctt gctaagacta
    49441 tgagtgattt agcagttaga ggtaatagta gtctctgttt tataatagga ggttctttag
    49501 ggctttctga tgaggtttta ggaagggctg attataggtt atccttttct aagatgactt
    49561 ttcctcatca gatgatgaga ttgatattgt tagaacagat ttatagggct tataggataa
    49621 ataatggaga accgtatcat aaataaatga tacggttttt gttaatttga cacttaataa
    49681 tattaaaata acaaaaaagt attgaaagta tattgcattt aaggtagaat taaataaaat
    49741 attataacat tataatgttt atatggttgt taataaaaat ttggaggaaa atatatgata
    49801 aaaataatgt tggcctgttc agcaggaatg tctacaagtt tattagttac taaaatggaa
    49861 agtgcagcta aagaaaatgg tatagagtcg caaatttggg caataccaga atcaactata
    49921 caaaatgaaa tagaaaaatg tgatgtatta ttactaggac cacaagttag atatgtatta
    49981 cctaaggctc aagaaattgc taagccatat aatataccag tagaagttat aaatatgatg
    50041 cactatggaa cagttaatgg agaagctgtt ttaaatagag cgatagaact taacaacact
    50101 aagtaatata aattataatg tatttttaat atataaattg ggagaatcaa aggatggatg
    50161 aaaagactat agaaatatct tttaatataa taggttatgc aggtgaaggt aaaggattag
    50221 cttttgaagc aataaaagag gctaagaatg gaaatataga aaaagcaaaa gaattattaa
    50281 aagagtctag ggaagttata aataaagcac atagatatca aacagaatta atacaaaacg
    50341 aagctagtgg aaacaggact gaaataagtg tcatacttat acatgcacag gaccacttaa
    50401 tgaatggcat gaattttcaa cagttagctg aggaaatcgt tgatttacat ttgaaattac
    50461 aagataaata aaaattaaag ataataaatt aagagagttc ttaaaagata cattatgtgt
    50521 agcacactaa ttgttagatt attgattcaa tatttagtga gtaatacatt aggattattt
    50581 tgaggactct ttttatattt agtttaaagt taataaatat ttattattaa taatataaga
    50641 ttatatgtta taatattata acatataatt taagaggtga atcatgttaa gaaatcaacc
    50701 attatatata caagttgtag atatattaaa gcaaaaaata ttaaataacg aatataaaat
    50761 tgatgaaaat attccaacag aaagggagtt agagcaagag tttggagtca gtaaaattac
    50821 tattagaaaa gctattgaga tattagaatc agaaggatat gtagagaaaa aaagtggaaa
    50881 agggacaaaa gtaataagta atagcctttt taataagcta tcaaaagcag agtctttttc
    50941 aagtatactt ttatctaaag gtcataagtt atctaaagag actatttcaa ttgaaaaaat
    51001 aataaatgat acaaattcac aagtatttag tatatttgga gaaaaatgta gcaagattac
    51061 tagaatgtat tatttagata gtaagccata tatatttttt actcattata ttccttttga
    51121 tgaaaatcta actgttgaaa gttttaataa tgaaagttct ttatatatgt acttatatag
    51181 gagaaatata aatataacta gatttgaaga tgaatttttt atagaagaat cagaactaga
    51241 ggtatcaaag gctttaaatc tagctaaaga catattatta ggaagaaaaa gaaagaccta
    51301 tgatgagaat gataatatag ttgagctatc atttgcaaga tataatacag aagtacaaaa
    51361 ctatgtaatt aaatacgaaa tataataaga atcctgagtt tattgaaatg ataatatgct
    51421 caggattttt gtttagttgt aaaaataaaa aatattataa cattataatg tttacaacca
    51481 aacattataa tgttataata tttttaataa acaagtgata ttatcaatta cataaaaatt
    51541 agtttatgtt atgaaatcgt tattgcatta taaataaagg ataatatcaa taatacaggg
    51601 ggataactat ggaaaaattc gcaagttttt tagagcgcaa gattatgcct gtagcagcga
    51661 agataagtaa tcagagacat atgagagctg taagagcagg tataatagca acattaccac
    51721 taacaatagt ggggtcattt ttcacaatat tattaaacat acctattgat gcttatatgg
    51781 attttatagc tccatttaaa gcaatattag atataccatt tagatatact gtaggatttt
    51841 tatctctata tgctactttt gggatagcat catcacttgc taaaagctac gatttagata
    51901 caacaggtgt tggtatgctt gcagttatgg catttttagt ttctacaata gttccaactc
    51961 aagtagttga accagtaggt ggagttatag aagctggtag atggatggat atggcaaaac
    52021 ttaattcgcc atcattattt ggagctatcg taacatcatt aattacagtt gaaatatatc
    52081 gttttatgaa ggaaaagaat attacaatta agatgccagc aggagttcca gtagaggttt
    52141 caaattcatt tactgcatta ttaccgacag cagtaatttt aatgttattc tgggtaataa
    52201 gacatattct aggatttgat ataagtgttg cactaagcgc tatgttatca cctttaaaag
    52261 gattcttatc aggaaatagt ttaggtggtg ggttactgac agtattccta ataactttat
    52321 tctgggtact tggaatacat ggtccagcta taatgggacc agtaataaga cctatatggg
    52381 acatgtctat agcagaaaat ataactgcat tcacagaagg agtatcagct catgcaatgc
    52441 caaacatatt tacagaacaa tttttacagt ggtatgtatg gataggggga gcaggggcta
    52501 ctcttgcatt agttgtaatg tttatgtttt ctaagtcaca atatctaaaa agtttaggta
    52561 gattaggatt tttaccaggg ttattcaaca taaatgaacc tataatattt ggagcaccaa
    52621 tagttatgaa tccaatacta gggataccat ttataattgg acctataata atgacaattc
    52681 tatcatatgt tcttactatt acaggggtta tacctatgat ggtagcaaga ttaccatttg
    52741 caatgccagc accaatagca gcagtaatga gtactaactg gagtatacta gcaggtatct
    52801 tagtattaat caactttgtg atatcatttg ctgtttatta tccattcttc aaagtttttg
    52861 aaaaacaaca attacaaaga gaacaagaag aaatgagtga aaatttataa aaatacatag
    52921 atatagaggt tttgtactat ataaaatata gaaaaagctt ataagttatt aagggtgaag
    52981 gtaggaggaa tgacctttgc ctttaatttt atatatttta aataatgtaa tttgaggagg
    53041 agaaagatgg aaagaagatt aggaatatca gtatatccag agcatagtaa catggaagat
    53101 gataaggcat atataaaaat ggcttcaaaa tacggattta aaagaatatt tatgtgcatg
    53161 ctttcaatta caagacctaa ggaagaagtt aaaaaacatt ttaaagagat tataacctat
    53221 gcaagagaat taggatttga agtaatcctt gatatagctc caaacatatt tgatatatta
    53281 caaatatctt atgatgattt aacatttttt agtgagttaa atgctagtgg aataaggctt
    53341 gactatggat atgatggaag taaagaagct atgatttctt tcaatccata tgatttaaaa
    53401 gtggaactaa atatgagtaa tgatgtagca tacttggata atataattac ttacaagcca
    53461 aatgtaaata atatatatgg ttgtcacaat ttttatcctc aaaggggtac aggcttgcca
    53521 tatgattttt ttgtaagatg ttcaaataga tttaaaaagt atggaataag aactgctgct
    53581 tttgttaatt caaaatacgc aacaataggg ccttggaata taaatgatgg gctgtgtacg
    53641 cttgaaatgc atagaaactt agatattgct acagcaacca agcacttatt cgcaacagga
    53701 ttgattgatg atgtaattgt agggaatgca tatgcaagtg aagatgaatt aaaaagaatg
    53761 tctgaagtaa ataaatatca agttgtattt aatgtagtaa ctgaagaaaa aacttctgaa
    53821 gtagaaaaga caataatggc aaatgagcaa cactttagaa gaggggatat aaccaaccaa
    53881 gtagcaaggt ctacagaagt aagaaaaaaa tatgctaaag aaaatttccc taagcatgat
    53941 aatacgacca tctttaaaag aggagatgta gtgattggta atgatgactt tggaaagtat
    54001 aaaggggaat tacagttgat acttcaagat tgtgcagatg aaagaaaaaa taaggtgggt
    54061 agaataaagg aagacgaaat aatactttta gactttattg aaccttggag taaatttaaa
    54121 cttattttag agggagagta aagtgaagat agacatatta ataaaatgtg gaaaaacagt
    54181 agataaaagt ataattgata tagctatatt agacgataaa ataatagaag taaaaaatca
    54241 gatagatgat tctaagtatc aggcaaatca aattataaac ctagatggag aaaaatttat
    54301 tagtgctggt tggatagata tacatacgca ctgctacgaa agactagacc tttataagga
    54361 ttatccagat gaggttggaa taaaaagcgg tgttactact gtagtagatg caggaacaac
    54421 aggagcttta gatataggta aattttatga agatactaaa aaatataaaa caaatgtata
    54481 tgctttaata aatattgcta agcagggaat aacatctcaa gatgaacttt caagtatgat
    54541 gaatattgat gaatatgaac ttagaagagc agttaaaaaa tacaaagatt ttgttgttgg
    54601 aatcaaagct agaatgagta aaagtgttgt aatttcaaat gatgttgaac ctttaaaagt
    54661 agctaaaaga ataaaaaatg aacttaatct acctatgatg gttcactttg ggagttctcc
    54721 tccaacgata gaggatatat ttgactatat ggaaaaagga gatatattaa cccatatata
    54781 taatggaaag ccaaatggaa tacttagagg caatgaggtt aaaaaagaaa tcatagaagc
    54841 tagagaaaga ggtataatcc ttgatgtagg tcatggaacc gaaagtttta gtatggatat
    54901 tgcaatgaaa tctaaggatg caggaatttt tccagacact ataagtacag atatatatat
    54961 taaaaataga ataaatggtc cagtgtataa tctatctaca acaatggaaa agtttatata
    55021 tatgggctat tcacttgaag atataataga taaagttact aaaaatgcag cagatgcaat
    55081 aagtttaaaa aataaaggtt taataaaaga aggatatgat gctgatttaa ctatatttga
    55141 tgtggttaat gaagaaaaag aacttcaaga ttctttgaat aagtcagtaa tcacaagtac
    55201 gtctataaag ccaagagcag tagtagtcaa tggagaatat ttaaatatag gtaagtctat
    55261 aggagagaat gagtagaagg gagaaactat tgtatgagta gtatatttga aaaatactct
    55321 gtaagacgtg ttataaatgc ttcaggcaaa atgactatac taggagtatc aacagtagat
    55381 aaggaagtta ttgaagcaat aggtgaaggg tgtaaaaatt tctttataat agaagaactt
    55441 ataaataaaa caggtgaata tatagcaaat ttattagggt gtgaaagtgc actaatagtt
    55501 tctagtgcat ctgctgggat tgcacagagt gtgggagcaa tgatagcaaa agatgatatg
    55561 agtctagttt acaatgtaaa taatcctaag aaacaagtta aaagggaaat aataattcca
    55621 aagggacata atgttgatta tggagttcca gtagaagtaa tgataagact tggaggagga
    55681 gaagttgttg aggccggtta tgctaatatg tgtaacaagg aacatataat aagagagata
    55741 aatgaaaata cagcagcaat tatgtatatt aaatctcatc attgtgttca aaagagtatg
    55801 ctaagtgtat tagatgcagt acaagttgct aaagaatata atttaccttt gatagtagat
    55861 gcagcagcag aagaagattt aaatgtatat tatgaattgg gagcagacct agtgatatac
    55921 agtggtgcta aggctataga gggtcctagc tcagggttag taataggtaa gaaaaaatac
    55981 atagataatg taaagcttca atcaaagggt ataggaagag ctatgaaaat aggaaaagaa
    56041 aatattgtag gtctaacatg tgcaattgag agatatataa gtaatgataa agtaacttta
    56101 aaagaaatgg aggataagct aaatccattt atagacaaga taaatactat aaagggagtg
    56161 agtgctagta taactaggga ttcagcaggt agagaaatac ttcgtggaga aattgacttt
    56221 aatgaagata taataaataa gtcaacacaa caaattataa atgaacttag aagtggagag
    56281 atagctatat acactagaga ctataaggct aatgaaggca agattgagat tgatataaga
    56341 agtgtaactg gaagtgattt agatactatt tataatagga taaaaaatat agtagaaagt
    56401 tagagtgtag agtaagtgac attataatga tttaataaat taaattttac caatggaggg
    56461 gataaatatg aattgtatac cacaatatta taaaaataga gtttgtttaa atgttcttgc
    56521 aggaagcata aaaaatgcta aagaagtata tgatgcttgt gacgggcatg tattgatagg
    56581 aatactatca aagaattata gcactgtaga agcagctatt gaagatatga aaaaatactc
    56641 aaaggaaata gataatgcaa tatctgtggg gcttggagct ggagacccaa atcagtcaaa
    56701 tatggtatct cagatttcta aagaacttca gccacaacat ataaatcaag tgtttacagg
    56761 tgtggctacg tctagagcat tgcttggtca aaatgatagt ataataaatg gattagtttc
    56821 tccaactggt aaaccaggat ttgtaaaaat atccacaggt ccattaagtt caaaagaaaa
    56881 agatggtata gttcctatag aaacagcaat agctatgatg aaagatatgg gaggaagctc
    56941 aattaagttt tttccaatgg gagggcttaa aacaaaggat gaatatatag aagttgcaaa
    57001 agcttgtgca aagcataatt tttatttaga accaacaggg ggtatagact tagataactt
    57061 caaagagata gttcaaattg cacttgatgc tggtgtagaa aaagttatac ctcatgttta
    57121 tacatcaata attgataaag aaacaggtga aacgaaagtg gaagatatag gagtacttta
    57181 taaaataatg aaagaattat tgggatagat ttatgaatat attagctttt ggtgaaataa
    57241 tgatgagact ttcagtacct gactacaagt tcttaacaca aaccaatgaa ctaaattata
    57301 taactacagg cacgggatta aatatattat ctggacttaa aaactttgga tacaatacct
    57361 atatgttgac aaagttgcct aataataatg taggtaaagc atcaagtgca aatataagaa
    57421 agcttggagt aaaagatgac tttatcacgt atggagggaa tcatatagga gtgtattttc
    57481 ttgaaaatgg gtatggagaa agaccttctg aagtgactta tttgaatagg ttaaatagtt
    57541 cattttgtga gagtaaatta caagattatg atattgataa atgtttagaa gaaatggata
    57601 tagtccatat ttgtggtatt gctatgcaac ttacagattc agttaaagag attgctttag
    57661 aactagctag aaaatcttat gaaaagggga taaaagtatt ctttgatttt aattttagac
    57721 aatcattaaa tccagaaagg acttatgatg atttagtaaa tgattataag aaaatactac
    57781 catattgtca tgggctgttt gctagttata gagatataaa taagatactt aatatagata
    57841 gtctaaatat aaaatctagt tcagaattga ttaaaaaaga gtatgatata gatattgtag
    57901 ctggaactat gagaagattt gatgatatga ataatagatt tataaaggga tatatatcaa
    57961 atgatgatgg ttattttgaa agtagggagt ataagctaga aatatatgac agggttggtg
    58021 ccggagatgg atatgtagca ggaattatat attcatattt ggaaaatatg aagagtgaag
    58081 atatagttga gtttggggtt gctagttcgg tgttagctca tacaacttat ggggataatt
    58141 ctttagtaag cacaggtcat gtacttagac tgatgaataa tgaaaaaata gatatattga
    58201 gataatacat ttgtatataa taaaattttt atctttttta gacacatttt tgacttgctt
    58261 atatttgtta aacagagtta tttttaatga ttataaatat taaattaaaa gttaaataat
    58321 aaaatagtag aaaatagcat taactataga aaaaatggtt aatgctattt ttatcgttaa
    58381 tattgattaa ttttatatta tagaaatgaa cttttctaat gctggatttg tatttttttt
    58441 attccataca actacaactt caattctatt ttctacttct tttataggta ctattgcaat
    58501 atcacgttct atcattgtat ctgtaacaca aaatgaaggt aaaatggata ttcccatgtt
    58561 agaagatacc aatgattcaa tagtattaag attatttgaa cgttgtacca cattaggtac
    58621 aaaccctgct tcacgatatc tattctgtat cattgacttt tgtccatact catcccctgt
    58681 ttcctttaca aaaataaatt tatcatgttg taattcaatt aaatcgatag aatcctcatt
    58741 gtaaagtgga tgaccaggag gtaaaagagc taccaaagaa tatctttcta cagttttata
    58801 ttcaaaatct tttaatggtt gattttctgg attaataaca aaagcgaggt ccatagaatt
    58861 attttttact aagtttaaaa gttcggttat ttcattagta caaatatcca tagatatatt
    58921 agggtatgta ttagaaaatt cttttaaata ttgttgaagt ttgttttttt catatcctat
    58981 taaggttcca atgctcaaag ttccaaaaaa accatgtgca aattgttgtg tttttgcaat
    59041 agcatcattg atatttttta ttatagtacg tgcctcagat aaaaaaactt ttccagctgg
    59101 tgttagttca acatgacgtt tacttcttgt aaatagagtt acatttattt gttcttctaa
    59161 agcttttatt tgctgtgtaa cagcagtttg agaaatataa aatttttctg ctgttttggt
    59221 aaaacttaga ttttctgcta cagatataaa atattctaat tgtttagtat tcaaataatc
    59281 acccctattt aaacttgatt gtttgtaaac cttatttatc tataattaaa gcttattata
    59341 gtataagaaa atttactttt aaagaatatt agaaaatatt tgtataaaaa tatatgtttt
    59401 aagtatatct ttacattaga ttttataaat ttattaataa gaataactta tatattccaa
    59461 tgaaaacgat attggattta agtaagtttg tctcataaaa tgaaagtata tcaattgata
    59521 atactttaaa taagaaggga gaaaaaatgg aagataaatt ttatgcaaaa ggcaacggaa
    59581 ataacggata tattaaaaat cttgaagttt gttcctttaa taacttagat ggaacttgtg
    59641 gaatgtttca aatggctctg tacaaaagag atgaaaaata ctatttatat ggatgctgtt
    59701 ttggaggaaa taaaaaaaat ggagtaatga ttagcgatat tacagaccct tataatccac
    59761 aatttataaa acattttcaa atgttagacc ctaaagagta tcctacaaca acaactccca
    59821 aaattcaaat agcagatgat ttaatgatag tagcaatgag ttgtggaagt ggaccaggag
    59881 cacttgttga ccaagctaaa ttagcaaata ttaagtgtga agcaggaatt agaatatata
    59941 gtttaaaaga agacccttta aatcctaagt ttttaggata ttgggattgt ggcttaaagc
    60001 atgtaatggg tgttcataga ttcatgtaca atggtggaag atatgtacat ttatcaagtg
    60061 attgtgttgg ctttgaaggt ctgatttata gggtcataga tataataaat cctactaatc
    60121 cagtggaaat aggtaaatgg tggagaccag accaatatgc agatggatat ccaaatagaa
    60181 cttttgatgc aggagcacct cattgcccag aatttatgga taaaggatgg cttcatggac
    60241 ctccatttgt aagagacgga aaagcatatt gtggttatgg aggagctggt ttagttgtat
    60301 tagatgttga agatttaaca agaccaagat gcttaggtga attgccattt atgcctgcat
    60361 tttctagtag acttgcaggt gcaagaactc atacagcatt accattgcca ggaagagatt
    60421 tagtcgttgt tcaaaatgag ggagaaagat tccagttctt taaaccagat aacattacag
    60481 atgttcaagc tatgaataat atacatatgg ttgatgttag tgacccaaca aaaccaacat
    60541 taattgctca atttccatat cctgaagttc caaaagattt cccttatcct aactttaatg
    60601 ttgcgggatt aggaaaacca gggccatttg gcccacataa tcttcatgaa ccaatggata
    60661 ataagccatg gttagagcaa agaggagata gagtatattg ctgttatttc catgcagggc
    60721 taagggttta tgatgtatca gacccatatt atatcaaaga gctagcatat tttataccac
    60781 caaatccaaa taaaacacca gaagaatctt atttcccagg attcccagga ccacgcttgg
    60841 cagtaacaga agatcttatc gttgatgata gaggctacat catcatagat gctttagatg
    60901 atggattcta tatattaaaa atgaaagaag attaaataaa tactaaagag ggagagttga
    60961 aaatgaaaat actaggtatt tcttttggaa caaaaaatgg aaataatgac acaatgtgta
    61021 aagttgcact taaaggtgcc aaagaagcag gggctgaagt agaatttatt caaatgtcat
    61081 ctattaacat taaacattgt actggatgtt gtgcgtgtgt taaaacttta ttatctggga
    61141 aaggtagtat gtgtgtatta aaagatgatt ttgaatggtt gcttgacaaa atgaaagatg
    61201 cagatggtat agtagtttca gaccctattt ttgaagaagg ggcatcagga ttattccata
    61261 ctataatgga ccgttttgga cccagagcag atagaggaaa taacattata ggaacaaaag
    61321 ttgcagaagc tataggagga aaaattccag attcaagaat gcttaatgat aaagtaatat
    61381 catttatggg aataggaggt tctgactggg gtacaagagt tcaatgtgaa catgctatgc
    61441 tagctctcat accaatgtgg aaagttatag ataatgcttg gttcccatgg gcaaaggaat
    61501 tagtaatgga tgatacaagg cttgttcaag ttcatcaaat tggtttaaat atagttgaag
    61561 cagcaaaaga ttttgaaaaa gcttcatatc aaggagaaga aggtgtatgt ccacattgcc
    61621 acaatagatt attctacctt gagccaggta ctaaaaaggc aatttgtgct ctatgtggta
    61681 tagttggaga gttagatact ataagtggaa aaactatatt tagttttcca gaagagcaat
    61741 taggtcatgc tcatgatact ttaccaggta agtttataca tggtgatgat attaagaaaa
    61801 tggaaggtca ttatgcagaa gttcgtaaaa cacaagaatt taaagaaaga aaaacatctt
    61861 ataattttat agagccatta actaaagaaa agcaagctgg agtttcatta ggataataat
    61921 taaaatacta agactctttt ttaaggtatg ttagatgtta taggaggctt attgtatgaa
    61981 tgaaaagtca agttttaaac aaattgaaat tattttagca gttatttttt tggtacttac
    62041 atattacaag gttagattaa ctccagcatt tattgttata tttataccac tatatttaag
    62101 ttattttgca gtatctatga ttgtaaatca aatagcaatt aagctattgg agataaggca
    62161 agctagggaa gctactaatt acaatatagg aaatggatag aaagaaaaaa gaaatattaa
    62221 cactgtctat ggggattgct ttactacctc ctttatgggc agtattagca ccttatatag
    62281 gaataaaaac tggagctgta gcactaatct gtgcaggatt atatgtaact aatggtaata
    62341 aacaaaaaga tggattaaaa ataatgtttg gtttttggtg tggagattta tgggcagtgt
    62401 tagccatttt aattatggga tatatgaatt tcaatcaaaa cctagaatta tttttaacac
    62461 ttagtatatt aggttttttt gcagttgtaa ttgcatcctt atttgaaaaa ataattttcc
    62521 taccatcatg gctttgtggt tgggctatag gtctaactat tatgacaggt gaaaatatta
    62581 ttaatttaca agatatttgt attcaaattg ctgtagctat ggcagtagga gtatggtacg
    62641 tgggtgcagg tgtagatttg tttacaatat atattttgag taaagatagg aaaaagggaa
    62701 attgaaagca tgtgaatata ctttgattat aggagaatgg ctatgggttt tgaatttaaa
    62761 ataatgagaa gtttaatata tgtaggactt gccaaggaag aatatagacc taagctaatg
    62821 gactggttat atcgtcacca tattccagat agtattagca cttttggacc atattgtact
    62881 aaatatgcct tttatcaagc atatcctaca ccaaatgaag gtgagcgttt tggtgcacgt
    62941 aagatgcaac taacagaaca ttattggctt gtagatgaac atatgcctga gatggcaaat
    63001 agaattatga cagaatatat gcctatggat gttctacgtt ggcaagggtg tataccagat
    63061 gtagaaaata aaagggttca tgaaaatgca gaaagtggag atgcaggacg tgcagtaggt
    63121 ggagataatg gatgtccacc atttatattt gcctttgttc caataaactg ggaagaagac
    63181 tttagaggaa aaggacgtac tgtacaagat ggaccaaact atcgttggca atttatgatt
    63241 aagtatccag atggtatctc taaagaagaa ggagaaaaat ggttctatga tgaggtagtg
    63301 ccatacttta caaactgttg ctatgttaat cgttttgtca gtagtaaaat aatgattaat
    63361 tatggagcaa ctgcttttga ccgtgtatca gaactatggt ttgaagggga agaagaatgg
    63421 tataaagctg tggttgaaga gacaaagtcg tttattaaaa aaccagaatg ggcacaagaa
    63481 gaggagttcc catatttaaa accacaattc aatatcgcat cagtattctt aggtgatata
    63541 gcaactatgg atgcatactc acagtatcgt ggatatatac caatgagata aaaattatag
    63601 tttgtgataa gtagaggagg catttactct tactggtaga agaagactta ttgtatcctt
    63661 aaaagtaggt gaatatatag ttttatattt aaatttatat aaaactaaga ctaataaata
    63721 tgaaacaata gaattagaat aatttgataa tatttgttaa aagagcattt agaatgtgtt
    63781 taaagattaa gatattcctt ttatggtagc agatagttga aataataaaa ctgttatcat
    63841 gaaaggaata tttttatgta taggaaattt ttaaaaataa aagttaaata tgtttaagaa
    63901 catcttaaag tgaaagaatc attgttagaa atatgtagac aatatagtct ttataacgta
    63961 tcatattaac aagtttacac ttggattatg aaataaaaag agtaattcca aaggttgtaa
    64021 atactatgct gactttgata cttcaaagtt taggtgattt tgtaattgtt aatagaaata
    64081 cgtttaatga gcataaagaa tttatctaat aataggagaa tataatgtat acaattggac
    64141 aagtatctaa atttttagga atatctagag atacactaaa attttatgag gacaaaggat
    64201 tagtaaatcc taagaaaaat gatgaaaatg gatatagaat atataatcag gttgatatct
    64261 atgatattgc aacaataaac ttttatagag aaattgatat agaaattaaa aagattcaag
    64321 aaataagaaa aagtaagagt ataaacaatt tagaactctt actagaagag aaggaacaaa
    64381 tcatactaaa agagatagaa tataaaaagc ttctcttaaa aaaggttcag ttagtcaaag
    64441 aagattgtga caaaataaaa acatattttg gaaaatacac aataaaagaa atgaagcctt
    64501 tggaagtaaa aggtaaaata aaacatgtta ctaactatga ggaatatgaa gccttaaaag
    64561 agaatacaaa caacttaaaa aaagcagtta cattaactga tttaagaaga gtaataaatt
    64621 ttaatgaaga aggtataata gaagaaaaat ttataattgt aagggaagta gatgactaca
    64681 acaaaatcat agaaggtgaa gttctatctc atcccaattg tatttatact attattgaag
    64741 atggcagatg gtcaactgga ggagaaaata ttgataataa agtggaagac agattaagag
    64801 aaatagcaat agaaaatgaa tgtgaattac ttggaatagt ctatgttaat atattgctta
    64861 ctacttatga agaagggatt gagcgtatat ttttagagat ttatgcacct ataaaataat
    64921 ataaaagcat tgacctggga cttactcata ggtttaaact catgatataa gcagttataa
    64981 cttatatagc aattaaatat taatttgaaa tgaggattac ttatgagaac agagaaatca
    65041 ttaaaaaggc ctatagccag ttttattatt ctaacaaata taattttttt accacttttt
    65101 ttattggtag tagtgactat aatgttaaaa cttccaacag tgatatctga cattgcgttg
    65161 tgtatatcag cgtggtcatc cacttttgca tttatgatat tatttaaaaa aatttatcca
    65221 ggtaagaaat ttttagtaca cgtaaaagat agatttagaa ataaacttaa attttcaaca
    65281 gtatctataa taattagtat acaagtccta atagctgtag tagttatatt tatattagca
    65341 tctaaaaatc atggaataat gcctaacttt acagtttcat catggggagc atttatatat
    65401 ttatttttaa aaaatttatt tgcaggatca ttaggtgagg aattaggttg gagaggattt
    65461 gttcaaaatc atcttcagaa aagacattct cctttaaaag catccataat agtaggtttt
    65521 tggtggggga tgtggcattt accaatatgg tttacaacag gattcaaagg acttgattta
    65581 ataaaatata ttatattttt tatgattgca attatatcaa tcagtattat aatgacaact
    65641 ttttataatc taaataaaac tttgataata cctattgtaa tacatcaact atttaatttt
    65701 ttaataggga taattaatgg agatttaata gagcttataa attactatgc aatgttatat
    65761 ttaatatttg caattgcatt aatagttata aatccaggaa atgtattata taaaaatatt
    65821 agagagtaat atatatcttt atggtaagat ataaagatat tattagaaga acatccaagg
    65881 aggaataaac atggttttac tgattgttga tgcacaaaag ttaataacaa acgagaggtt
    65941 atataaattt aatgaatttg tagtaaatgt agaaaattta attgatacag ctagaaaaaa
    66001 taatatagaa gtaatatatg tacgtcatga tgatggagtt gaaaatgaat tgactaaagg
    66061 taaaaatggc tttgaaatat acgaaaaatt taaaccatgt aatggagaaa aaatatttga
    66121 taaaaaagta aatagtgctt ttaaagaaac tggtctatta gaatacctaa caaataatgg
    66181 tgaaaaagat attattattg ctggtctcca aacagattat tgtattgatg ccactataaa
    66241 atgtggattt gaacatggat ttaatataat agttccagct tattcaaata caactgttga
    66301 caattttttt atgtcagcag aacaatcata taaatactac aatgaattta tatggaatga
    66361 aagatatgcg aagtgtattt cattagagga aacacttaga aaaatgaaat aaaaatagag
    66421 tatgaattgt atatgtacat aagttgattt cataaaaaag gatgttaaat tccaagttaa
    66481 aaattagatt aaatatatta tattatagat aaggcacatc aattttattt taaattaatg
    66541 tgctttttaa ttgtagtaat ttatttataa tcaatatgat ttttattatt taaatcaatt
    66601 tttcttgagt ttctttgtct aaagaaactt tttttattta taaaatctac agttatatta
    66661 tagtatctat tttagagaag tttaattttt gtatcaatct aaaacaaaag ttatacttaa
    66721 atgaaattga aaacgataaa attctcaaat aaaataagta ttgtggaggt gatgaaagaa
    66781 tccaatgata atatgaagac taatcttaat aagaaagtag gggttaatgg tagtggacaa
    66841 agaaattgta tcaattctcc agattttatt aaatagcaca ttgattacaa ctaatggatt
    66901 acaagaggag tctaattcat caaagagaca aattacttat agaataaata aaatcaatga
    66961 catgcttaaa gtaaaaaatg taccacttat atgtttaaga gctgataaag atattatcgt
    67021 tagaaaagaa acaaaaaaag caattaaaga aattttagaa aaaaactatt ctaagaatac
    67081 ttattatttt agtaagacag aaagactttt atatatgtat ttaatgcttt ttattaacat
    67141 ggatgatatt tcaattaatc attttataaa ttctataaaa gtaagtaggt ctactgtaaa
    67201 tcttgatttc aaggatttga taccagagct tgaaaagaag aacattaaag ttaagaacaa
    67261 tcgtataaat ggatattaca tagttggcaa tgagatggaa attaggagag tgcttattaa
    67321 aaatattata gaaactttgt ctaatgagaa aagttcaaga gtatttgata tttttattaa
    67381 agaatataat ttagatagtt ttgaagaggc taaaaaaatt atattaaagc taataaaaaa
    67441 atatgaaatt acttttgttg aagatagatt agtagaattt atatatatat ttatctttct
    67501 aaaggcaagg atgtattcaa ctagaatagt tactcaggaa aatgtagata ttcctaatat
    67561 ttcagttatg agttcaatga aggagtataa atttgctaag gaattattag aagtatatgg
    67621 gagtgaagat aagataaagc ctcacaatat aatgtatatt agtgcttgga ttttaggtat
    67681 atcagtagga aattatgaag aagatacaga agataaggat gtaatttcaa aaattgtaaa
    67741 taaaatgatg acaaagtttg gatatttaag cggagtttac tatataagcc aagaaaaaat
    67801 atttaaacaa ttatattctc attttagacc tgcctactat agacttttat ttaaattacc
    67861 tatttataat ccgatttgtg aaaaagtaaa agaagaatat aaattagttt atagaattgt
    67921 aagtaatgca atgaaagagt tttgcggatt atttggagaa gaaattcagg aagaagagtt
    67981 agcatatctt acaatgcact ttgcaacact tttttcaaat aaaaaagaat ttgatggttt
    68041 tagaaaaaga atagcattaa tagtttgttc aaatggcgtt ggtagttcag ctattttaca
    68101 tgcagaactt acaaacttat ttcctgactt acactttata ccaatgtcgg aatcagttgg
    68161 attagaaaat ataagtgaac ctgtagatat tgtatttact actaattata acgcagaggg
    68221 tttaaaaaca gatgtaccag taattaaagt aagccctgtt atgaccacaa aagaaaaata
    68281 taagattaca cgtgaagtgt atattcaatt aggtgatatt tttttaagac aacctaaaat
    68341 agatgaggtt atggatataa taaaaaaata tgcaaatgta acttctgaaa gtattctttc
    68401 aagtgagcta ttagcttatt ttacacagat agagaatttt acatctaagg aaggagaggg
    68461 gcctatgcta agtgagatta ctaatgaaac actagtaaaa ataaaggtaa aagctaagaa
    68521 ttgggaggaa gctattagac agtcagcttc tgtattagtt gaaaataaca aagtaactga
    68581 agggtatgta gatgctatga ttaactcagc aaaagcatct ggaccataca tagtaattac
    68641 aaaacatgtt gcacttccac atgctagacc agaagctggg tcaaaagaga ttgcaatagg
    68701 cattgctact ttagatagtc ctattgagtt tgggaataac gaaaacgacc ctgtaaaata
    68761 tgtattttgt ctaagtgcaa tagacaataa tagccattta cgtgctatgt ctgagctagt
    68821 tgaactattg gaagaagatg agttttttaa ggttttagat agtgctaaag aagctaaaga
    68881 aattattgat tttataaaaa cacacgaatt ataaaggagg atttaattat gtataaaatt
    68941 ttaatcgcat gtagagcagg agttggctca agtttaatgt taaaaataaa gactcaacaa
    69001 attattaagg aaaataactt tccaattgaa gtagaacatg gttcattgga ttcactaaat
    69061 ggattcaatg gagatgctgt agaaacatta attgatgttg ctgaagaatt aaaaaataaa
    69121 aatttgaagt ttgatataat tgggattcac aatattgttg accgtaatga aataaagaca
    69181 gcactagaaa aattccttgc ttcaaaagag ggataaattt aagatgataa ggaggaatat
    69241 ttatggagtt tattattagt ttgctgagta cacctgctgt tttgcttggc gtagttgcat
    69301 gtataggatt gattcttcaa aagaaatcag ctgttgaagt atttacaggc tcttcaaaaa
    69361 cacttatcgg ttttttgata tttggtattg gtgcctctgc tatgacagga gcacttcaaa
    69421 atttcaataa actgttccaa catggctttg gaattactgg tgttatagct tcaccagaag
    69481 cagctacagc acttgcacaa ggtacatatg gttttgcagt ttcatgtaca ttaattcttg
    69541 gattcatatt aaatttagta tttgcacgta ttacaaagtt taagaatatt ttctttacaa
    69601 caggtcatag tttgttcttt tcttgtgtat tagttttaat tatgaaagca catggatttg
    69661 ataatacaat cactatttta ataggtggaa ctatcttagg gtttatgtct gctgcactac
    69721 ctcaattctg tcaaccattt atgcgtgaat taacaggtgg cgacgaacaa gctattggtc
    69781 actttaacat gattggttat ggtttatcag gttatattgg gcgtttattt tcaaaacata
    69841 aagatgatac aacagagact atagaatttc ctaagtggtt atcaatattc agagacttct
    69901 taatgggtct atccatagtt atgttaatct tattttatat tgcaacatta aaagctggtc
    69961 aagcatttac tcaagaaatt gctggttcaa cacattggtt ggtttttccg cttatagagg
    70021 catttacatt tgtggcaggt atgtcaatat tgatgtcagg agttcgtatg ttcttagctg
    70081 aaataactgc agcatttgta atcatttcag aaaagtatat tccaggttca cgtcctgcgc
    70141 tagatgttcc aaccgtattt ccatatgcac caaatgcagt tattattggg tttatatcag
    70201 catatgctgc tggtctatta gcaattgcta ttatggcatc atttcctagt atatttcctg
    70261 tagtaattat tccagctgct cacatatgtt tcttctcagg aggtacagct gcaatatttg
    70321 gcaatacttc aggaggatgg agaggggcta ttgctgggtc atttgttgtg gggttattac
    70381 ttgcattttt accagttata ctatatccag tttatgggac tcttggtata gaaggagcaa
    70441 ctttccctaa tattgattac aacgtagttg gttcgatatt acataatatt ttacaattta
    70501 taaaacctat ttagactaaa ttatataaaa gtatagtcat agttactatg atttcaagga
    70561 ggatacatct tatggaaaat acattatctg aatttttaga taatatatct aatgaattgt
    70621 cagaatttat tgcctcaata gatgagacat ctataaataa agcatgcgaa ttaattcttg
    70681 aagctgaaaa aaatcacgga cgtgtacatg tgactggtat tggcaaacca ggacatgtat
    70741 cgggatatat ttcatcattg ctttcatcta ctggaacgtc agcatatata ttgcatggta
    70801 cagaagcagt acatgggtca agtggtcaag tagttgaagg agatgttgtt attgcaatat
    70861 caaatagtgg tgaaactcaa gagttaaaag caactcttaa gactctaaaa gtaaatggag
    70921 caaagataat tggtgtaagt ggtaatgaga gttcattttt aaaaaatatt tctgatatat
    70981 tcctgtttgc aggtgttaag caggaaggag attgtctcaa taaagctcct cgtgcttcaa
    71041 ttttagctga aacaataata ttacaatcat taagtgttgt attacaatat gctaaaggtc
    71101 ttaatacaca ggagtatttg aagtggcatc cagcaggaag tcttggaaag tctattagag
    71161 agggaatata attttatgaa atataaaggg attatatgtg caatgataac accatttgat
    71221 gaaaatcaaa atattaattc acaagcaaca tgtcaattaa ttgattattt gattgaaaag
    71281 ggaatttatg gattatttat tttgggcact aatggtgaat gtcatgtatt aacagatgat
    71341 gaaaaagttg aatttgcaaa gattgttatt aatcatacaa ataatcgtgt acctgttttt
    71401 gttggaacag ggggtaattc aactcgtgaa gttgtagatt tatctaagag aatggaagcg
    71461 attggagcaa gtgcattatc tattattaca ccatactttg ttacaccaac acaacaggaa
    71521 ttaatcttac attacaaaac tattgctaat tcagttaatt tacctattat aatgtataat
    71581 atgccaggta agactggaat taatattgaa ccagagtcag tacgtgaatt atcaaagata
    71641 aagaatattg ttggaattaa ggatagtagt ggtaaacttg acaacatgaa agcttatatt
    71701 gaagcaacga agaatgagaa ttttagtgtg ttttcaggct cagattcact tattctggat
    71761 agtctaaaag ctggtagcca aggagctgtt gcagcaacaa caaacttcct cacagagatt
    71821 ggtatctcta tctatgaaaa ctttatgaaa ggggatttgg aagaagctca aaaatctcaa
    71881 agtagtatag aagaacttcg acgtatactg aaacttggaa caattccatc tgttatgaag
    71941 aaaactattg tcttgaatgg aattaatgtt ggaactgcac gacttcctgt aactgaacca
    72001 actggggaag tacttgaaga aattaaacga gtagttgaaa attataggac aatacttaat
    72061 aaaagtagtg agaatagata atataaatag ggaaattaca ctggtatata attaatatat
    72121 atattataaa acatgactaa aattaatgaa taagtaaagt ggtttgatga gtatagaggt
    72181 gataatatga aaaagatgaa tataaccaaa agaatgtcag aatgtggggc tcttgcaatt
    72241 gtaagagaag aaaatcttaa ccgtgcatgt gaaattgctg aaggatgtat aaaaggtggt
    72301 ataacagtta tagaaatgag ttatacccta aataatgctg gagaaataat tcaagggctt
    72361 aataaaaagt atggtgaaat actttgtgtg ggagcaggaa cagttttgga tagtgaaaca
    72421 gctcgtcatg ctatattaca tggagcccaa tttattattg caccaaatta taatgaaggt
    72481 gtagcgaaga tttgcaatag atatcagatt ccttatgctc caggatgtac atcattgact
    72541 gaggcagtag acgcactaag tttaggagca acttttataa aagctttccc aatatcagat
    72601 ttctatggac ctaaactagt aaaggtattt aagacaccaa tacctgatat gccagtttta
    72661 gcaagtggag ggcttaatat tgaaaaccta catatatggt tagaaaatgg agttgatgta
    72721 tgtggatttg gtggtttatt aactaaaggt tctgttgaag atattgctaa aaatgctaaa
    72781 aagattcgtg aaatcattaa aaatgtaaga aaaatttaac atagggctgt atcatagtat
    72841 cttataatta ctatgataca gcctttttaa tattattcaa atttaaaaca gtttacattt
    72901 ctattatatt acatataatt tcagtaattt tatcttaatt tttctatctg gaaaaaaatg
    72961 atttaaaact taagttatga tataatttca ttaaaagaag gcgattttta gtaaatatga
    73021 gaaaataatg tgtttttagg ggaaaagtta aatacagatt taagtgaaca agaatcgata
    73081 attaagatat taaatggtga atagggcatc aaaaaaatta ctaaattaaa agttttagag
    73141 ggagaatctt agcaagtgtg tgtgaaaatt caatttcaaa caaaaataat tgtaaatgaa
    73201 atcaatttat acacgttgaa gattcacttt tatcattata ttaaaaagca gagtgaatta
    73261 aaagtgagtc taaagatagg aggataatta aaacaatgaa agaagacatt aggttacatc
    73321 gaatgtgtaa aaaagaacaa gcaacaaaga atgaagttat atcagaggat attctaaaat
    73381 ctatgagtat tggggtcagt aaacattttt tagatgattc atttacaata atatggggaa
    73441 atacatcatt ctatcaatta ttaggatata cagaagaaga atttttagtt aaattttcta
    73501 gtttaaaaga ttattatgaa cagaatcttt atcattttga atctatgaaa aatcattttt
    73561 tagaggctta tcatcatggc gaaaagagta tagaatatca aatttgcatt tcagcaaata
    73621 atggagaccc tgtttgggta ataatgactg gtatattaat tgaatcacaa gataatgaga
    73681 aatcaatggt ctatatattg tattcaaaaa ttaatgagtt aaaaataaag caagaagaac
    73741 tatctgatat ggaaaaagag agtacagaga attttaaatg gatgatgtca gagtatgctg
    73801 ggaatgttta tattagcgat atggatacat atgaattact atacttaaat aagcactcat
    73861 gcaatacttt acaggcatca gcaaatgaac ttattggaag aaaatgttat gaggtaattc
    73921 aaggtagaac ttcgccatgt ccgttttgta caaattcgta tttaaaaaaa gatgacatat
    73981 atgaatggga attttataat aaaaaactga aacgaacatt tataattaaa gaccgtatgt
    74041 tgaattggca agggcgaaga gttcgtattg aattatctta tgatatgtat agtgctgaat
    74101 ataaattagc aaaaaaagat caggaaagag aatcaatttt gaaaactatt ccagcaggaa
    74161 tggttagatt agatgcaaga gattatctta ctatactttg gtgtaatgat atatttttga
    74221 atatgattga atatacaaag gaacagtttg cagaggaact taataatcaa tgtggatatt
    74281 tattttctga agattataaa cgtagtaaga aactggcaca agatttgaag gagtctgggg
    74341 ataatgttgt atttgaagca aaaatatata cacgttcaag ggaagaacgt atatggactg
    74401 ttacattgtg ttatatcagt ggggaagaca gttgggatgg aataccatct ttttatagta
    74461 taggtattga cataacaaag gaaagaaaac agattgagaa attacagcat atatcagaga
    74521 aagatgcatt aacaggaatt tataatcgtg ctgagactga aaggcagatt aagaaatatt
    74581 ttgaaaaaaa tttaaatgtt atgggtgcac tgtttatgat tgatacagat aattttaaac
    74641 agattaatga tacagaaggg catatgattg gagatatagt acttactgag atggcatcag
    74701 gtatgaaaaa aataatgcgt gacagtgatg ttgttggaag aataggtgga gatgagttta
    74761 caatttttat gaagaatatt tcctcagtta aagatgcaga aaagaaagca gaagaactat
    74821 tgtatatgtt ccgtcatcta tttcagaaag aaaaaagttt tctaaaagta acttgtagca
    74881 taggaatagc tatatatcca aaggatggta ctacattcaa ggaaatatat gcaagagctg
    74941 ataaagccct gtatcaagca aaaaatatgg gaaaaaataa ttatgtaatc tacaaccaag
    75001 attattttaa agaattagaa gaatttgatt gttcttctct tggtacagtt attgattcag
    75061 aaaaacaata cgctgaatat cctgataatc ttacacgtta tatattccgt atgctttatc
    75121 agactgatga tatagaccag gcgattaata tgatacttga ggttgttggg aaacagtttg
    75181 atgtaagtcg tgtttatatt tttgaaaata cagaagatgg tagatatact tctaatactt
    75241 atgaatggtg taatgaagga atctcttctc aaatggctta tttgcaaaac agcaattatc
    75301 aagactatga ggattatgaa aagctttttg aggatgaatt agttttttat tgtcgagata
    75361 tccatacatt aagtcctaaa ctagaagaat tgttttctag tcaaggtatc cactctacac
    75421 ttcaatgtgc atataaagaa gatagagttt tcagtggatt tgttggattt gatgaatgca
    75481 caggactacg tctatggtca caagaggaaa taagtacatt atcattgatt tctcaaatta
    75541 tatcaatgtt tttacaacgt aaaaaaaata ataaacttaa tcaacagatt caacaatacc
    75601 agaatatttt agataatatt gaccagtgta tttgtgtgat taataaagaa aataattttt
    75661 tattatatgt aaataaaaaa tttaaaaata catattctaa attccaaatt ggacaacctt
    75721 attatcttga ttctatagat attcataaga tatccattat atggaataaa aaagaagcat
    75781 acctatgtac tagcacgatt taatggtaaa gtaaagttta tattggactt aaattaaatt
    75841 tcgttttaaa taagatatta ttttagttgc ttactgaaaa gactagaatc tatattaatg
    75901 aattatacta attttatacc actattaaaa tattgtttgc taaaaataaa aaatagcctt
    75961 aaaacagttg attataaaaa attaactgct ttaaggctat ttttatcttt gtgacgaaat
    76021 agacacttgc catttagaat gtgacaatat agtagttgtt tagaaaaggc acaaagcatt
    76081 atactttaac taaagtaaaa tgtattttgc ttttagaata aaaacaatta ggagggagct
    76141 ataattgaaa aagataatat atgtattatt tacaattgaa ctattaatag tatctttatt
    76201 aggtctaaat atagttaaag ataatgaaat taataatatt ttatataacg atacaacaag
    76261 tatatctgta atgtttaaag attataaaaa gttaaataaa aattatagta agtggattaa
    76321 agatattgca gatgaaaata atgtggctat atcaaagtat gtttttaata ataatgaaaa
    76381 attatctata tatacgactg atacaagttt gaataacaat ataaagttaa aatcaggaaa
    76441 atttcctaat actaattcaa atgaatttat tagtaatata aacactaata atagtaatca
    76501 agtaggtaaa ttctcaacta tgagtaaaga catatcaatt ttaattaggg attttggtaa
    76561 aataagtgaa gttggagaat caggaatctt atatatttca actcaaaatg aagatacaat
    76621 aaataaaata ttaagagaac taaatgtaga cagaagtatt tttgtagcaa gattacatga
    76681 tagatatgtt aactcaaatt tatacttaaa tccttcaata attagagatt taatactaat
    76741 tatcctttgt ttcttggcta caataataca ttattcaatt agtgtgagta gagaggcttc
    76801 tattttaaga ttaaatggat actctaagct agatataatt gctagagtta taaaaaatat
    76861 acttagaatt atgattttat catctgtcac agcattatta atatatataa tctatatttt
    76921 aaaattaaat ataggtgtta gagcatgctt atactttgct atgttttcga ttatatgtat
    76981 tttgataaat attttgatat ctatattaat agttggtttt aatagtagaa gttctaaata
    77041 tgtgctatct ctaaatggaa aaaaatctta tggttttgta aatataatgc atttcacatt
    77101 gaaaattgta tttgtatcat ttcttatatt atccataaat aactgtattt taaattataa
    77161 tatgctacaa actcagttag gaaatctatc tgagtgggat aaagcaaaaa atgtttataa
    77221 tcttactctt aaagatacag gcgaacaatc tttaggaaag gaagaagtaa ttaaaaatgc
    77281 caagattaaa ggtttctata aaaatttggt agaagaaaaa gatgctttct taatagattc
    77341 aactaatttt gaaaaacttg aagatggaag ttacatgtat gaaataaatt caaagggtaa
    77401 aaacccagaa gtaagtcaat atggtaaaaa tataaaaata aataaaaact atcttaaagt
    77461 taaccctatt tactcaaatg gcaaagaaat atttaatcta atcgattatg acgataagac
    77521 tataaattta ttagttccta aaaagttaca agtacatgaa aatgagatta aaaaagagtt
    77581 tagagaatta ttttattttg aaaaaataga agtagaaaat atgtacaata aagagttaaa
    77641 tagagagtta aataaaacaa agaagtccga tttaaatgtt aatataatat atgtagataa
    77701 taatcaaagc tattttactt ataactccct tgttatggat gacaatagga atctcattga
    77761 tgacccaata gcaatagttg acatagataa tattgatgat tctttttatc tttcttatat
    77821 atctagatgt gtatatttta attctaagaa attagatgcc cttgcagata taagtagcat
    77881 tattgaagct caaggtgtag aagcgcatat ccaaagttta catgctgttt ataatgagta
    77941 tggtttagaa ataaataaac tagaaaaata tttgaatagt gaaattttta ctataataat
    78001 aatagcaata tcaaacttaa tgattaccta caatatagta gctagctact atgaaagaaa
    78061 taaatataag ttatatatta aaaaaatatt tggttactca actacagcta gaagtatgtt
    78121 gttaatagtc tcattaatat taacaaacat tattccaata ggcattatat caacaagagt
    78181 agatttaagt aataatatta tcttatttgg acttctaata ttagttatag aagtaattgt
    78241 atctattgta ttagacaaga ttatctcaaa tagttcattt aataaaatta taaaaggaga
    78301 acattaaaaa gatgatttca ttaataaata tatctaaaaa atttaaagat aaatctataa
    78361 tagacaaatt taacctagaa atttctaagg gcgagtttgt agcgataaca ggaaatagtg
    78421 gttcaggtaa gacaacttta cttaatataa tgggattatt agaaaaacct aattctggtg
    78481 atattataat aaataatata aaaaatccaa atagtaaaca gataagaatt ttacaaaggg
    78541 atttttatgg ctatctattt caaaattatg ctttaattga gaatgaaaat gttgaaaata
    78601 acttgaaaat tgctttaaag tatcaaaaaa atatcaatca taatgaaaaa ataaattacg
    78661 cacttgagtc tgtaggtctt agaaaataca agaaaaaaaa gatatacgaa ttgagtggag
    78721 gagaacaaca aagggtagca ttagcaagag taatattaaa agaatgtgaa gtaatatttg
    78781 cagatgaacc tacaggtaat ttagataaaa aaaatagaga catagtattt gatatactta
    78841 aaagtctaaa taagaatggt aaaactatcg tatttgtaac tcatgattta gatttatcgg
    78901 agcaggcaga tagagttata aaattgtaat aatataaact ataataaata taagaaagag
    78961 attacagcta aattaagttt aataataata cgaatagaat ttaaacatta agtaaattag
    79021 tagtttgtaa atataagtat aatatgatat cataaaggct caaaagaaat tttatataat
    79081 aagaaatcta aaaataacaa atggaggaca tataaagatg gaaaatttac caaattgccc
    79141 gaaatgtaat tcagaatata cttatgaaga tggaactctt ttagtttgtc cagaatgctc
    79201 tcatgagtgg gcattaggat tgggagctga agaagattca aatattatca aagatgtaaa
    79261 tggaaatgta ttaaatgatg gagattctgt tacagtaatt agagacctta aagtaaaagg
    79321 aagttcatca tctataaaga ttggaacaaa agtgaaaaat atccgtttaa tccatgactc
    79381 atcagatgga catgatatag aatgtaagat agatggtttt ggagctatga agctaaagtc
    79441 ttctgttgtt aaaaaagcgt aatattataa ataagctgta gtgtttattg tttttcagta
    79501 cagtataaaa ccataagaat ctattaagta ataaaagttt gtttatttat ctttatattt
    79561 tcttatggtt ttattaaata taaattttat tgaacaccaa aatattctct cctctacaaa
    79621 taagccaatc ttatttaaac taatatactt tgtactattt atactgaaat tgtaaattta
    79681 aatgctatgt tatttaggtt tgtatagtta atttatatat ttctgatttt ataaattgta
    79741 tttattatta tatcttgatt ctaaaatcat taaaaatttc aacttctata aagatttaca
    79801 atttatcaaa tacattatga gtatataaac aatttattat tacagtgcta catttaaaat
    79861 aagtcttagt ataaaggtat tgttacaagt ataaagaaac ttatgtatgc tattggaata
    79921 aataatacct taaattataa ttaagaataa gaactgttaa ataagggact tgattatcat
    79981 ttagttatag ataatataat attaaaaata aagtttaaga ggagaaaaaa tatgatagat
    80041 atacataaaa atatatatga taataagtta tttgaggagc taaagattga ctgtaagaag
    80101 tgctttggac tttgctgtgt agctctttat ttttctgctt cagatggatt tcctatcaat
    80161 aaggaatcag gaaaaccctg tattaattta caaccagatt ttaaatgttc tgtacataat
    80221 agtcttatta agcgaggttt taaagggtgt actgcatatg attgttttgg ttcaggtcaa
    80281 aaagtagcac aagtaacata taaggggata gactggatgc aatcaccaga actaacaaat
    80341 caaatgtctg aagtgttttt aattatgaga caattacatg aaatgttatg gtatcttaaa
    80401 gaagcatctg tattaaatat atcagataca atcaaatcaa aaattgattt aataattgaa
    80461 gaaactgaaa agataactaa tatgggccca gaacagataa ttaatttgga tatcatatca
    80521 catagaacaa aggttaattt attattatca caagcgagtg agtctatgat gggaaaggtt
    80581 aaatcattta tcaagacttc tactcttaaa aacatgaaaa aattaagtaa aaatatagat
    80641 ttaataggag cagaccttag aaaaataaat ctaataggag cagatttaag aggtagattt
    80701 ctaatagcag caaatttaag aaatacagat ttgagtgggg caaatttaat aggagcagac
    80761 ttaagagatt gtgatattag aggtgctaat cttgaaaata gtatattttt aacacaatta
    80821 caagtaaata ctgcaaaagg agattctagt acgaagttac cagcttcact aatacgccct
    80881 aaatactggg aaaaataatt aaattaatac ataattttac aaaatatgaa cttttttgac
    80941 tttaattcat attatacatt agagattctt tacaagaatt tcttaatata atatagggag
    81001 agatataaaa atgagttatc aaaattataa atgtgaaaga gattatgtgt atgatgatta
    81061 taaatacaat aagtgcaaca agtgctataa tgattatgag gaaatgacac atgttcatga
    81121 atattcagaa agtgttaagt tagcagaaga atgtgaggat agacataacc accgtgcagc
    81181 aggggttact ggtgaagtta taccaataaa tggaggtaca aatcatgttc ataaaataaa
    81241 tgataatgta gatttccttg accatttcca taagatatgt gttacaacag ggccagcaat
    81301 tagaatacct ggaactgata aacacattca cttaatatgt ggagaaacta ctgttaatga
    81361 tggtcattgt cataaattcc tttttactac tcaaatagaa gcacctttag tataagctga
    81421 tgtgaattat tgtagtgaat ttgctagatt atagtataat atataataga taatatttaa
    81481 acttaatgag gactatgata tttaaccttc gtagtccttt ctaagttttg tataaaaaag
    81541 tgttatgcaa ttaaaagtga tatagggagg aaatttttat gaaatctgga ataattcttg
    81601 aaatgaaaca aataaattca acagaatatg acgaaatgtt gcaagtctgg gaatcatcag
    81661 taagagcaac gcatgatttt ttaacagaaa aagatattga atctttgata ccattagttg
    81721 agattggact taaagaagta gaaaatatag tttgtataaa agataatgat ataataaagg
    81781 gctttatagg aatagataaa gataaaattg agatgctctt tatagaagat aaatatagag
    81841 gaaatggtat tggtaaaaaa ttaataaaat atgctataga taaatacaat gtaaaatatg
    81901 ttgatgtaaa tgagcagaat aaaaaagctg taggatttta tattcactta ggatttaaag
    81961 tgtttgatag gtctgaaata gatggacaag ggaacccatt tccaatacta catatgaaat
    82021 taatttaaag ttatacttcc cacttattcg caaaaatatt tacttaaatt tttatacaaa
    82081 taaaagtcgt gacagtctta ggacacgact tttttactac actattaaat tgaaatttat
    82141 ctgttctata ttatgattat tagatgtagt ttttttattt taactatgta cttaaatacc
    82201 aagtataccc atacctatca agtacttcag cagcgccatc attttgatgt ggtggtgggt
    82261 gtggtaaaaa ttcttgtaca agtgtaccac cttcggcaag ttttacagat atttcttcta
    82321 tcgcttctcg agatggtaga acaacacaaa tcgccatgcc agaaattaca acaggcttgt
    82381 ctgtatccgc acccattata caaccttcgt attttgtgaa agtaacactt gcgtgcataa
    82441 taggattgtt tggattgctg tctaatcgcg caaatatagt ttttcctcct ccgaaagcct
    82501 cagcataaaa attaaatgct ttttcacaag taccattaaa tattaaatat ggagttagca
    82561 tgaccaatat atcctccttg atatagaata atttatagtt gcacctgata atctaaatta
    82621 tgatttagta aattgtatca tagggaaacc ttgaagtata taatttttta ttattatatt
    82681 atacaaattt attaatttaa aaaaatgtta tatgtacgga aggtttacag gataaaatat
    82741 aataaaaaga ttaaggtgac attataaaaa atgtatattg acattgacgc tacgtaattg
    82801 tatatacttt gtcttaaagg agatggtaaa tatgaatatt atagaaattc gctcagataa
    82861 aatatacaag aagataatgg atgcaccaat aaacaaaaaa gaagatatat acagatatga
    82921 attaatgaag ccttttgaat ttaagtggaa gtgtatgaat gttccaatag ttgctagaca
    82981 gaaaggtgga tatgatgtaa ttatagcaag tgaaatgtta ggggttttat cgcctaagga
    83041 tattgatgaa aagcaaaaaa agaatataaa tgtgttatct gctgataaaa tttggggcac
    83101 ttgcaaagaa accatagaaa actctataaa tgcttttata aaagaagggt atgatttaaa
    83161 cattaaggac tataaatatt caatattatt ggcgaatcca aatagtcctt atacaatatt
    83221 aagtgatgga tactggggtg atggtgggat tcctggatat atatttctat cattggttcc
    83281 taatgaatat actatcaata gattaccagt attaatagca catgaatgta atcacaatat
    83341 tagatttcag tttatagagt ggaataataa tataacatta gaagaaatga tgataaatga
    83401 aggtcttgca gaaaattttg caacatggat gtttggagag gaaatgttag gaccttgggt
    83461 cagtagaaca gatatcgaaa cattaaatac ttatataaag ccaataataa aaagtgcttt
    83521 aaaagaaact ggatttcaaa atataacatc ttatctttat ggtgatgata tagctaaaat
    83581 gcaaggatat tttccagtag ggttgcctta ttgtgcagga tatgcttgtg gatattatat
    83641 gattaagtat tatttagaaa agacaaataa atcaataatc gaagcgactt tattgcctta
    83701 tagtgagata atcgaagcag taaaagagtt ttgggaataa attttataaa ttgcataatt
    83761 tgaaataaat tatgcaatta ttttattttt aagaaaaaat aaattgacaa taatttataa
    83821 gaaatataca ataatatata taaagaaata tttcaatatt taaaagtttt aagatttcat
    83881 atctagagta gctaacatta catgttagtt tcttgttact tatctaatta ctttatattt
    83941 cgtagttata tataaaatta ctataaaaaa tgaaatatat taaacaatca actgaaaaat
    84001 gaaatgttaa taaaaaaaaa tt
//
LOCUS       DAEPXW010000003        77521 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.003, whole genome shotgun sequence.
ACCESSION   DAEPXW010000003 DAEPXW010000000
VERSION     DAEPXW010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 77521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77521
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.003"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..869
                     /gene="rsmA"
                     /locus_tag="KRM55_000159"
     CDS             <1..869
                     /gene="rsmA"
                     /locus_tag="KRM55_000159"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBH1592432.1"
                     /translation="DRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGARI
                     TRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTELVNQDIL
                     KVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRMN
                     AIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHNE
                     DIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFSV
                     LSNIINTKVSSK"
     gene            935..2182
                     /locus_tag="KRM55_000160"
     CDS             935..2182
                     /locus_tag="KRM55_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592433.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEDNEESDRDEDSEE
                     EYDEDEYEDYWEDDEDIEEGELKARTEVEDSGDEEIEEFNNYKEIENYNRVKVQEEYI
                     DIEYDEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQGESGNK
                     QTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLGYLNVL
                     NYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFLRYQAC
                     DNRTNSLGYWLCFIDSRQRNIVR"
     gene            2333..3448
                     /locus_tag="KRM55_000161"
     CDS             2333..3448
                     /locus_tag="KRM55_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1592434.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIIAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            3634..4530
                     /locus_tag="KRM55_000162"
     CDS             3634..4530
                     /locus_tag="KRM55_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1592435.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISIMIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            4600..5397
                     /locus_tag="KRM55_000163"
     CDS             4600..5397
                     /locus_tag="KRM55_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592436.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(5453..6805)
                     /locus_tag="KRM55_000164"
     CDS             complement(5453..6805)
                     /locus_tag="KRM55_000164"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBH1592437.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            7024..7905
                     /gene="purR"
                     /locus_tag="KRM55_000165"
     CDS             7024..7905
                     /gene="purR"
                     /locus_tag="KRM55_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBH1592438.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDEDY"
     gene            8058..8336
                     /gene="spoVG"
                     /locus_tag="KRM55_000166"
     CDS             8058..8336
                     /gene="spoVG"
                     /locus_tag="KRM55_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBH1592439.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            8549..9928
                     /gene="glmU"
                     /locus_tag="KRM55_000167"
     CDS             8549..9928
                     /gene="glmU"
                     /locus_tag="KRM55_000167"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBH1592440.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            10023..10973
                     /locus_tag="KRM55_000168"
     CDS             10023..10973
                     /locus_tag="KRM55_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBH1592441.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      11812..11897
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            12059..12580
                     /locus_tag="KRM55_000169"
     CDS             12059..12580
                     /locus_tag="KRM55_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1592442.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTTTDKAGLTILETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTDTEGVTLTEAQSAKLLSDIGKDKIYTGVTGDNFGDELTDTTKIDNKALY
                     IVLIDNTVMDSTK"
     gene            12732..14408
                     /locus_tag="KRM55_000170"
     CDS             12732..14408
                     /locus_tag="KRM55_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH1592443.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            14420..15628
                     /locus_tag="KRM55_000171"
     CDS             14420..15628
                     /locus_tag="KRM55_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH1592444.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            15643..17355
                     /locus_tag="KRM55_000172"
     CDS             15643..17355
                     /locus_tag="KRM55_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBH1592445.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            17348..18256
                     /gene="pilO"
                     /locus_tag="KRM55_000173"
     CDS             17348..18256
                     /gene="pilO"
                     /locus_tag="KRM55_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBH1592446.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            18283..18849
                     /locus_tag="KRM55_000174"
     CDS             18283..18849
                     /locus_tag="KRM55_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1592447.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            18886..19413
                     /locus_tag="KRM55_000175"
     CDS             18886..19413
                     /locus_tag="KRM55_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1592448.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            19434..20972
                     /locus_tag="KRM55_000176"
     CDS             19434..20972
                     /locus_tag="KRM55_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592449.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRDISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLEKLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            21072..22154
                     /locus_tag="KRM55_000177"
     CDS             21072..22154
                     /locus_tag="KRM55_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBH1592450.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGINPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            22135..22917
                     /locus_tag="KRM55_000178"
     CDS             22135..22917
                     /locus_tag="KRM55_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH1592451.1"
                     /translation="MDIIIVNLYVFMVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            23019..23669
                     /locus_tag="KRM55_000179"
     CDS             23019..23669
                     /locus_tag="KRM55_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH1592452.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNI
                     VQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            23683..24243
                     /locus_tag="KRM55_000180"
     CDS             23683..24243
                     /locus_tag="KRM55_000180"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBH1592453.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            24260..27646
                     /gene="mfd"
                     /locus_tag="KRM55_000181"
     CDS             24260..27646
                     /gene="mfd"
                     /locus_tag="KRM55_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBH1592454.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            27677..28672
                     /locus_tag="KRM55_000182"
     CDS             27677..28672
                     /locus_tag="KRM55_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1592455.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            28796..29335
                     /gene="spoVT"
                     /locus_tag="KRM55_000183"
     CDS             28796..29335
                     /gene="spoVT"
                     /locus_tag="KRM55_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBH1592456.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            29455..31068
                     /locus_tag="KRM55_000184"
     CDS             29455..31068
                     /locus_tag="KRM55_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH1592457.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            31175..32623
                     /gene="mazG"
                     /locus_tag="KRM55_000185"
     CDS             31175..32623
                     /gene="mazG"
                     /locus_tag="KRM55_000185"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBH1592458.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            32712..32990
                     /locus_tag="KRM55_000186"
     CDS             32712..32990
                     /locus_tag="KRM55_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBH1592459.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            33062..33304
                     /locus_tag="KRM55_000187"
     CDS             33062..33304
                     /locus_tag="KRM55_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBH1592460.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            33366..33620
                     /locus_tag="KRM55_000188"
     CDS             33366..33620
                     /locus_tag="KRM55_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBH1592461.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            33621..34154
                     /locus_tag="KRM55_000189"
     CDS             33621..34154
                     /locus_tag="KRM55_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592462.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            34160..34444
                     /locus_tag="KRM55_000190"
     CDS             34160..34444
                     /locus_tag="KRM55_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBH1592463.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            34557..35477
                     /locus_tag="KRM55_000191"
     CDS             34557..35477
                     /locus_tag="KRM55_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBH1592464.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            35567..37939
                     /gene="spoIIE"
                     /locus_tag="KRM55_000192"
     CDS             35567..37939
                     /gene="spoIIE"
                     /locus_tag="KRM55_000192"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBH1592465.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVESIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            38290..40182
                     /gene="pepF"
                     /locus_tag="KRM55_000193"
     CDS             38290..40182
                     /gene="pepF"
                     /locus_tag="KRM55_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH1592466.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            40296..41261
                     /gene="galU"
                     /locus_tag="KRM55_000194"
     CDS             40296..41261
                     /gene="galU"
                     /locus_tag="KRM55_000194"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH1592467.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            41761..43365
                     /gene="rho"
                     /locus_tag="KRM55_000195"
     CDS             41761..43365
                     /gene="rho"
                     /locus_tag="KRM55_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBH1592468.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            43518..43718
                     /gene="rpmE"
                     /locus_tag="KRM55_000196"
     CDS             43518..43718
                     /gene="rpmE"
                     /locus_tag="KRM55_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBH1592469.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            43863..44756
                     /locus_tag="KRM55_000197"
     CDS             43863..44756
                     /locus_tag="KRM55_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBH1592470.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            44774..45622
                     /gene="prmC"
                     /locus_tag="KRM55_000198"
     CDS             44774..45622
                     /gene="prmC"
                     /locus_tag="KRM55_000198"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBH1592471.1"
                     /translation="MTIKDIIIKYSDKLKDLSDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            45666..46730
                     /gene="prfA"
                     /locus_tag="KRM55_000199"
     CDS             45666..46730
                     /gene="prfA"
                     /locus_tag="KRM55_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBH1592472.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            46859..47539
                     /locus_tag="KRM55_000200"
     CDS             46859..47539
                     /locus_tag="KRM55_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBH1592473.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            47568..48608
                     /locus_tag="KRM55_000201"
     CDS             47568..48608
                     /locus_tag="KRM55_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBH1592474.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            48625..49074
                     /locus_tag="KRM55_000202"
     CDS             48625..49074
                     /locus_tag="KRM55_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBH1592475.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            49091..49543
                     /gene="rpiB"
                     /locus_tag="KRM55_000203"
     CDS             49091..49543
                     /gene="rpiB"
                     /locus_tag="KRM55_000203"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH1592476.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            49579..50208
                     /gene="upp"
                     /locus_tag="KRM55_000204"
     CDS             49579..50208
                     /gene="upp"
                     /locus_tag="KRM55_000204"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBH1592477.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            50503..51318
                     /locus_tag="KRM55_000205"
     CDS             50503..51318
                     /locus_tag="KRM55_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBH1592478.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            51544..51981
                     /locus_tag="KRM55_000206"
     CDS             51544..51981
                     /locus_tag="KRM55_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH1592479.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            52166..52393
                     /locus_tag="KRM55_000207"
     CDS             52166..52393
                     /locus_tag="KRM55_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBH1592480.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            52398..52784
                     /locus_tag="KRM55_000208"
     CDS             52398..52784
                     /locus_tag="KRM55_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBH1592481.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            52787..53491
                     /gene="atpB"
                     /locus_tag="KRM55_000209"
     CDS             52787..53491
                     /gene="atpB"
                     /locus_tag="KRM55_000209"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBH1592482.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            53560..53820
                     /gene="atpE"
                     /locus_tag="KRM55_000210"
     CDS             53560..53820
                     /gene="atpE"
                     /locus_tag="KRM55_000210"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBH1592483.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            53943..54440
                     /gene="atpF"
                     /locus_tag="KRM55_000211"
     CDS             53943..54440
                     /gene="atpF"
                     /locus_tag="KRM55_000211"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBH1592484.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            54437..54982
                     /locus_tag="KRM55_000212"
     CDS             54437..54982
                     /locus_tag="KRM55_000212"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBH1592485.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            54999..56501
                     /locus_tag="KRM55_000213"
     CDS             54999..56501
                     /locus_tag="KRM55_000213"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBH1592486.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            56529..57407
                     /gene="atpG"
                     /locus_tag="KRM55_000214"
     CDS             56529..57407
                     /gene="atpG"
                     /locus_tag="KRM55_000214"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBH1592487.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            57420..58814
                     /gene="atpD"
                     /locus_tag="KRM55_000215"
     CDS             57420..58814
                     /gene="atpD"
                     /locus_tag="KRM55_000215"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBH1592488.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            58817..59077
                     /gene="atpC"
                     /locus_tag="KRM55_000216"
     CDS             58817..59077
                     /gene="atpC"
                     /locus_tag="KRM55_000216"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBH1592489.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            59539..59919
                     /locus_tag="KRM55_000217"
     CDS             59539..59919
                     /locus_tag="KRM55_000217"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBH1592490.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRDEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            59934..60395
                     /locus_tag="KRM55_000218"
     CDS             59934..60395
                     /locus_tag="KRM55_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH1592491.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            60416..61006
                     /locus_tag="KRM55_000219"
     CDS             60416..61006
                     /locus_tag="KRM55_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592492.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            61021..62178
                     /gene="alr"
                     /locus_tag="KRM55_000220"
     CDS             61021..62178
                     /gene="alr"
                     /locus_tag="KRM55_000220"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH1592493.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            62211..62498
                     /locus_tag="KRM55_000221"
     CDS             62211..62498
                     /locus_tag="KRM55_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBH1592494.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            62467..62850
                     /locus_tag="KRM55_000222"
     CDS             62467..62850
                     /locus_tag="KRM55_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBH1592495.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            63021..63848
                     /locus_tag="KRM55_000223"
     CDS             63021..63848
                     /locus_tag="KRM55_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH1592496.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            63841..64782
                     /locus_tag="KRM55_000224"
     CDS             63841..64782
                     /locus_tag="KRM55_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH1592497.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVSVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            65205..66299
                     /locus_tag="KRM55_000225"
     CDS             65205..66299
                     /locus_tag="KRM55_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592498.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            66525..66941
                     /locus_tag="KRM55_000226"
     CDS             66525..66941
                     /locus_tag="KRM55_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592499.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKYV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(67123..67692)
                     /locus_tag="KRM55_000227"
     CDS             complement(67123..67692)
                     /locus_tag="KRM55_000227"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBH1592500.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            67846..69003
                     /locus_tag="KRM55_000228"
     CDS             67846..69003
                     /locus_tag="KRM55_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBH1592501.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            69607..70089
                     /locus_tag="KRM55_000229"
     CDS             69607..70089
                     /locus_tag="KRM55_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1592502.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIYINEF
                     "
     gene            complement(70662..71816)
                     /gene="nagA"
                     /locus_tag="KRM55_000230"
     CDS             complement(70662..71816)
                     /gene="nagA"
                     /locus_tag="KRM55_000230"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH1592503.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK"
     gene            complement(71899..72624)
                     /locus_tag="KRM55_000231"
     CDS             complement(71899..72624)
                     /locus_tag="KRM55_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1592504.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITTGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            72891..73820
                     /gene="pfkB"
                     /locus_tag="KRM55_000232"
     CDS             72891..73820
                     /gene="pfkB"
                     /locus_tag="KRM55_000232"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH1592505.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(73943..74860)
                     /locus_tag="KRM55_000233"
     CDS             complement(73943..74860)
                     /locus_tag="KRM55_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH1592506.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     ICSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            75331..76500
                     /locus_tag="KRM55_000234"
     CDS             75331..76500
                     /locus_tag="KRM55_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1592507.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPQGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            76549..77400
                     /locus_tag="KRM55_000235"
     CDS             76549..77400
                     /locus_tag="KRM55_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH1592508.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
BASE COUNT        30918 a         8411 c        14043 g        24149 t
ORIGIN      
        1 tggatagact atcttcacat aatgcaacaa aggaagtagt acaaaaatat aattttaaat
       61 tttcaaagtc tttaggtcaa aatttcttga tagatagtaa tataattgat aaaatcttat
      121 ctggagctag aatcacaaga ggagataata tcatagaagt aggacctggt ataggaactc
      181 ttactcgtga gatgggtaaa atagcagaaa aagtagtggc tatagaaatc gatagaaatt
      241 taattcctat attgaaagat accttgtcag atttagataa tacagagctt gtaaatcaag
      301 atatactaaa agtagacata caggaattag taaaagataa attaaatggt gggccagtta
      361 agcttgtagc aaatcttcca tattatataa ctactccaat agttatgaaa tttttagagg
      421 aagacatacc tgtaacagac atagtagtca tggttcaaaa agaagttgca gatagaatga
      481 atgctattcc gggtactaaa gattatgggg cattatctat agctgttcaa tactattgtg
      541 atacagagat tgtggcaaaa gctccaagac atatgtttat accacaacca aatgtagatt
      601 ccacagttat aggtctacat gtaagagata aaagaaaata tgatgttcat aatgaagaca
      661 tattttttaa aacagtaaaa gcatcctttg gacaaagaag aaaaactctt cttaattcgt
      721 tgggaggtct tggttttctt aataaagatg aaataagaga aatattaaaa gaagctaata
      781 tagacgaaaa aagaaggggt gaaactctta gtatagaaga gttttcagtt ctttcaaata
      841 taataaatac aaaagtatct tctaaataga aggtactttt tttaattttg ttaacatata
      901 ttgtttagag aaactgtgtt aaggggggat tgcagtgggt tctaaaagaa agtttaaaag
      961 agactatata atactagaag ctaaagacat aaactttaga tacaaagaac gagtactgcc
     1021 aaaagctttt gcaaaagttg aagtaaatga tgaaaaagca attattgcat tatatgtaga
     1081 aaatctaaaa tatgttaaag atgggtataa agcagtagca ataaaagatg accatggatt
     1141 aatagactta ggaaatataa ttttaaatga acaaggaaga ggtgaatttg ttttagattt
     1201 agaagattat gatgatgaga taaaaggtat tgcattattg tatgaaagaa atataccttt
     1261 aattggattt aagggaaata agcttgaaaa ttatgaggac atattatttc aagaagtaga
     1321 ggaagaagaa tatgaagaat atgaagagtt ggaagaagaa gacgaagaga tagaggataa
     1381 tgaggaaagt gatagagacg aagatagtga agaagaatat gatgaagatg agtatgaaga
     1441 ctattgggaa gatgatgaag atattgaaga aggagagtta aaagcaagaa cggaagtaga
     1501 agattctggt gatgaggaaa tagaagagtt caataattat aaggaaatag aaaattataa
     1561 tagggttaaa gtacaggaag aatatataga catagaatat gatgaggaag aagaggaaga
     1621 agaagttttt gaagtaaata gagaagaaga taggtttgtt tcctcaaaac ctactaaatc
     1681 aaagaaagtt caaaaagatc agaataatat tgaaaaaata aaaagagcta atggagtaag
     1741 tcaaggagag agtggaaata aacaaaccag tacattactt atgccaagac aaataaaaaa
     1801 aggtttgaaa ttatttaaag aagtaaaacc ttttgtaaca gattatatag ataagacaag
     1861 atggtggaaa atagagataa atcctacaac actgtgtgga tatacaatgc cttatttagg
     1921 atatttaaac gtattgaatt acactatgta tagtgatgca gttttacatt catataaata
     1981 cagacactat ttatttggag ttcagtatga tgaatataat aagagaaaac attatattta
     2041 tgctatccca ggaaatagaa atgaacagcc agacaatgga agcacaggat ttttaagata
     2101 tcaagcttgt gataatagaa caaatagttt aggatattgg ctatgtttta tagattctag
     2161 acaaagaaat atagttaggt aaaaataata aaaatgaaaa aatttagact caattcttat
     2221 tttactgaaa aaattaatga aatgtagtac aaaactttaa aaactattga taatatttaa
     2281 atattacact acaatatatc ttgaaatacc tattatatta tggaggaaaa ttatgataaa
     2341 cgagcaaaga attttaaatg agtttcttga attagtacag atagatagtt tatctttaaa
     2401 agaggggaat gttgctaaag tattagttaa aaaattagaa gaaataggtt gttcagtagt
     2461 aatagacaat gctggtgaaa aagcaaatgg agaaactggt aatataatag ctacattaaa
     2521 aggaaataaa gaaggaaaga aaatattatt tagttcacat atggatacag taactccagg
     2581 tataggggta aaacctatag tggatgaagc aaatggaata ataaaaagtg atggtactac
     2641 aatattaggt tctgatgata aagcaggtat agcagctata ttagaaggct taagatatat
     2701 aaatgaaaat aatatagaac atactgatat acaagttgta ttctctatat gtgaggaatg
     2761 tggattagtt ggagctaaaa atttagacta tggaaaaata gattctgaat atgcatttat
     2821 attagatagt ggtggttctc caggtgaaat aatagtaaaa gctcctgcac aagatgtaat
     2881 aaatgttaag atattaggaa agactgctca tgcaggtctt gaacctgaag ctggaataag
     2941 tgctataatg gtagctgcca gagcaataga aaatatgaat ttacttagaa tagacgaaga
     3001 aacaactgct aacataggaa ttataaacgg tggaacagct acaaatatag taacaggaga
     3061 agttaatata attgcagaag ccagaagtct aaaagaaaat aaattagatg ttcaaactaa
     3121 acacatggta gagacttttg aaaaagctgc aaaagatttt ggagctcaaa ttgagataga
     3181 tgtcaataga gcatatacac caatagatgt tagtgaggat tctgaaataa taaaacttgc
     3241 aaagaaggct ttttcaaact taggtataga aggtcatact gaatctacag gaggaggtag
     3301 tgatacaaat atattaagta agaatggtat cgaagctata actttaggaa ttggtatgaa
     3361 aaatgctcat acactaagtg aacatatagc tataaaagac ttatatgatt ctgctaaaat
     3421 ggtagtggag ataataaagg aagcataaat ttaaataata gtgtataata tatatatcgc
     3481 ctagcttaag ctaggtgatt tttcatttta tagaagattg ataatctcta ttgaaagcaa
     3541 agagtataca tttgcatata agagagtgtt taatttatgt tcaaatgtag gttcttaata
     3601 atatttagat tgtttcataa gggaggaata aatatggaaa caaggtatga agaagcaaat
     3661 aaaataacaa tacaatcaat actttggaat gtagtattaa caataattaa ggttatagct
     3721 ggtgttattg gtaattctag cgctatgatt gcggatggat tacattcagc atcagatatt
     3781 ataagttcta taggagtact aataggcaat tatgtatctt ctagacctgg agatagagag
     3841 cataattatg gtcatgagaa agcagagaca ttagtatcat ttgtgttatc aatattgctt
     3901 attttcgttt ctataacaat aggtatagag gcaattaaat ctttatttaa cttagatgca
     3961 ttaagtgttc catcaatatt accattagta gtatcagtta tttcaatcat gataaaagag
     4021 tatcaatata gaataacaat aaaagttgct aaaaagataa attcaccagc cctaaaagct
     4081 gatgcttggc atcataggtc agatgcttta tcttcagtag ctgcttttat aggtataggt
     4141 ggttctattt tagggtttaa accattagac ccaattgcgt cagttgtagt ggctatattt
     4201 gtagctaaag taggaattag tatacttata agttctgtta atgaattgat ggatgtttca
     4261 gttgatgaag aagagataaa agaattaaaa tttattgtag cagatacaga aggtgttaaa
     4321 aatcttggtg atataaagac tagaaaacat ggagctatgg catatgtaga tttgactata
     4381 tgtgtggatg aaaatttgac agttaagcaa ggtcatgata ttgctaccaa gcttgaaaaa
     4441 catataataa aacatatgga atttgtaaaa ggcataacag ttcacgttga accatgtact
     4501 aattgccaag gaaataagtg taataattaa ttaaaactta aaaaaaagtg taaaaagtta
     4561 tataattgtt ttatgattat aaactctagg ggtggttaaa tgagcaagaa aagaaaacta
     4621 aagaaaaaag ctgcaatatt aataggagta gttgttttct ttataatata ctttatatcc
     4681 tttagaatag gaataaatat ggaaaaggat aaaagtgaag tgccaaagaa ggtagaaaaa
     4741 gaagaagaag ataataggtc tttaaggact caaataaaag agaagaagaa ggtttatata
     4801 tcagataaaa atatagaaaa cataaaaatt gaagaagata tgtgggatga aataaagtta
     4861 tttttctcag attttaagaa agtaagaaat actacttctt cttacgaagc agtttatgaa
     4921 ggttattctg atgatggagt taaattttct actgacctta acttttttag agtatatact
     4981 gtaaataaag aagaatatta taaagtacca gttagttcta aggatgcttt taagaaactt
     5041 ttagatgaga gtatatatac ttcgtttgac cttttaagtc attataaaga ttggaaagag
     5101 gttactataa ctcatggaaa agaaattaaa aaagttcata gatggaaatt tgatgattta
     5161 gcacataaga tgatttcaaa gagagttgta ggaaaagttc aacctgagaa aagtaaggaa
     5221 agaagtgact ataattttac tataaatata aaaggtgata attttgatgt aaaagttgat
     5281 acaatgggaa aagattatgt aaaagttact tctaagaaaa atgtatctta ctatgaggtt
     5341 catacaagtt tatttgatta ccttaaaaat gagatatttg aaattggaaa gaaataagac
     5401 tttaagaagg ctatcaaatt agatatttga tagcctaaat tatttttata tattattttt
     5461 caaccaacaa gtctgcaacc ttataaattg gaccagcacc agcagttatt actaaatcat
     5521 tatccttaac attttcacgt aagtatttta ctatatcttc aaattctttt atatagatgg
     5581 catctacatt gttttgatat aatttctcaa ccaagtcctt agaatgtata tctcctgggt
     5641 ctttttccct agcagcatat atatctgtta tgataacttt atcagcagca tagaatgcct
     5701 ctgaaaattc acctaaaaga gattttgttc tagtataagt atgtggctgg aagatacacc
     5761 ataaagttga tttttttaat tttttggcag cagctaaagt tgcttttaac tcagttggat
     5821 gatgtgcata atcatctact actaaagcat tcttataata ccctttagtt tcaaatcttc
     5881 ttccgacacc tttataaatt tttatatttt ttcttatagt ctctaagtca ataccagaaa
     5941 caagagctgc cattatggca gaagaagcat tgtatatgtt atgaagacca tatacagaaa
     6001 gttcaaattc tcctaaatct cttccttcat attctattct aaatattcca tgaccactat
     6061 tgtcaaagtg aatatctttt attacagcat cattgtcaga atctctgccg tattttataa
     6121 tagtagcttt aacatcatac aatatatcat caatattttc atcatcgcca tttattatga
     6181 aatagccttc tgggggtaat aattttccaa atttgttaaa agaagccttg atttcatcta
     6241 ttccagagaa ataatcaaga tggtcttctt caacatttaa aactatagat atctttgggt
     6301 taaaattaag gaaactatct acatattcac atgcttcagt tataaagtgg ttggaattac
     6361 ctatcttaac attaccacct atcatactta agttaccacc aactagtata gttgggtcta
     6421 agtctgcata ttcaaagatt gtagataaca tagatgttgt agaagttttt ccatgtgttc
     6481 cagaaactgc tatagaattt ttatattccc tcatgatttg gcctaaaaaa gtcgctctgt
     6541 tcattaccaa tttatttttt tctttagcag ccacaagttc ttcattgtct ggatgaactg
     6601 ctgctgtata aacaaccata tttacatcat ctgatatatt atcttttttc tgaccaatat
     6661 aaatagttgc cccttggtcc ctaagtttgt ctaataggta tgattcgttt gaatccgaac
     6721 ctgaaacttg ataaccttta ttgatacata tttcagctaa tgcactcatg ctgataccgc
     6781 caattcctat aaagtgtata ttcataataa aaccaccttt ctttttaatt aagtcctaca
     6841 atatgaacta tttctgtggt ataataatat aatgttcaat attttataat taatatgcat
     6901 ataatattat atgtatttta tttttgaata taataaaaca taagtaatat tataccacaa
     6961 taagaattgt tatgcattag ttagtttaac gttatataaa ggtacttgta ggaggaaata
     7021 ataatgaaat ttaaaagaac agagagaatt ggagcaatag ttaaaatact gtctgataat
     7081 ccaaataaaa tatatacttt aagttatttt acaaatcaat ttaatgcagc aaaatcaaca
     7141 ataagtgaag atttattagt tgtaaaaaat gtatttgaga agctacattt aggtaaagtt
     7201 ataactattt caggagcagc aggaggagta aaatatatac ctaaaacttc tatagcagaa
     7261 aatgcagagt tcttaatgga attatgcgag agaatatgtg acaagtctag aatactatct
     7321 ggtggttttt tatacttgat tgacctaatt tacgacccta caatagctgc taagatagga
     7381 aagatattcg catcaaatat tgagtatgta gatgcagatt atgttgtgac aatggaaaca
     7441 aaaggtatac ctatggcact tatgactgca aaagctatga atttacctct agttataata
     7501 agaaaagata taaaggtatc agaaggtcct acacttagca tgacatatgt gagtggaaac
     7561 agttctaaag ttgaaagtat gagtttgcca agaaaagctc ttaaaccaga tagtaaagtt
     7621 ataattatag atgatttcat gaggggtgga ggtactataa aaggaatggt agaccttatg
     7681 aatgaatttg gtgcagaggt tataggtact ggagtattca tatctacaac gaatccttca
     7741 gaaaaaatgg taaaagatta tatttcattg attcaattgg atgttaatgg agataaaata
     7801 gtagtagaac caaacttaaa gacttttaaa gatgaatata gaaatgaaga tttagacgaa
     7861 gaagaagatt cagaatttga atttgagata gatgaagatt actaaaaaaa atatttagaa
     7921 aaatatgtaa aaataaaaag aggatatccc tagttgttca tagaattatt taaaaaacag
     7981 tttatattaa tttattccag cgataataat tttaatataa attaatttct gtcaaaatca
     8041 aagggggata ttttggtatg aagataactg acgtaagagt aagaaaatta acagaagaag
     8101 gtaagatgaa atgtatagtt tcaataactt tcgataattt gtttgtagtg catgatataa
     8161 aagttataga aggccataat gggctattta tagcaatgcc tagcagaaaa gtaggcgaag
     8221 gaaatttcag agatatagct catccaataa atgcagaaat gagacaagtt ttagaagatg
     8281 cagttttaca agcatatcat gaagcattag ttcaatggga agtagctgct gaataataat
     8341 aaatatataa aatggagaga gcccgaacat ttaggctctt tttaaatgta gaatttctat
     8401 taaaatatgt actttttagt aaaaaagtgc tatattatta gtgataatgt atatgttgta
     8461 tacaaattgt tagataaatg tattataatg tatattgatt aagagaataa tacgaataaa
     8521 attaaattag attgaatgga gtgtatcaat gaactttaaa gctataatcc ttgctgctgg
     8581 caaaggaaca agaatgaagt ctaaataccc aaaagttata cataaagtat gtggaaaaga
     8641 aatggttaac catattatag atgtttcaaa aaaatcaggg gtaaaagata ctgtcgtgat
     8701 tttaggacat gaagctgatg tagttaaaga aaagcttgca gaagaaatta taatagccat
     8761 gcaaacagaa caacttggga caggacatgc tgtaaagatg gctaaagaat atattaatga
     8821 tgaagataca atagttgtac tttgtggaga tactccactt ataaaagaag agacactaaa
     8881 gagactattt gaatatcata tagaaaataa atatcatgct acagttctta caacaagagt
     8941 tggaaatcca acaggttatg gtagaataat aagagataag aagggtgacc ttcttaaaat
     9001 agtggaacaa aaagatgcaa attcagaaga aaagatgata agtgagataa actctggaat
     9061 ttattgtttt aatggaaaga gtcttagaga agcactagat ttgctaaata ataacaattc
     9121 acaaggtgaa tattatttaa ctgatactgc taaaataatg agagataaag gattaaaagt
     9181 tggtgcattt gcaggttcaa ctattgaaga acttatgggc gttaattcaa gagtagaatt
     9241 atcaaaggca gaagaaatta tgagacgaag aataaatgaa tctcatatgg taaatggagt
     9301 aactataata gacactaact ctacctatat agaatctgat gttatgatag gcaatgatac
     9361 tataatatat ccaggtgtta tgttacaagg aaaaacaagg ataggttcag attgtataat
     9421 tggaatgaat tcatctataa caaattcaga aataggtgat ggtacagaaa taaaaaattc
     9481 aactataatt gatagtaagg ttggagaaaa ttctactgtt gggccatatg catacttaag
     9541 accaaagagt gacttaggaa ataatgtaaa aataggcgat tttgtagaag taaaaaatgc
     9601 tattatagaa gatggctcaa aagcatctca cctttcttat ataggagatg cacatgtcgg
     9661 taaaaatgta aatattggat gtggagtagt atttgtaaac tatgatggta aaaataaatt
     9721 taaatcaata gtaaaagaca atgcgtttat aggttcaaat tctaatttag ttgcaccagt
     9781 agttgtagaa gaaaaaggat atatagcaac aggttcaaca ataacacatg atgtcccaga
     9841 tggtgctttg gcaatagcaa gagaaagaca agttatcaaa gaaggatggg tagaaaaaaa
     9901 gaatcaaaaa gacgaccaaa gtaagtaatt atgtagttta ttattttggc taaaaaattt
     9961 agctcgaaat tattataaat tatattcatt agtattttaa aattttcagg agggttacat
    10021 aaatgaatac tagcggaagc gagattaaaa ttattgcagg taattcatcg aaagagttag
    10081 cacaaaaaat agctgactat ataggtgtat cagtactaga ttgtgaagta ggtacattta
    10141 gtgatggtga aatatgtgta aacatgaatg agacagtaag aggttgtgat gtgtttgtag
    10201 tgcaatctac taacagccca gtaaatgata acttaatgga gttattaatc ttaattgatg
    10261 cgttaaagag agcatcagca ggtagaataa cagcagttat tccttactat ggatatgcaa
    10321 gacaagacag aaaggctaag gcaagagatc caatcactgc taaattagtt gcaaatttaa
    10381 taactgctgc tggagcagat agagtattaa caatggattt acatgcagct caaatacaag
    10441 gatattttga tataccatta gaccacttac taggtggaac aatattagca aattatttta
    10501 atgaaaagaa aatagaagat ttagtagtag tatctcctga cttaggaagt gttactagat
    10561 caagaaaatt tgctaatact ttaaatggag aagttccaat agctataata gataaaagaa
    10621 gaccgaaagc taatgtatgc gaagttatga acttaatagg tgatgttaaa ggtaaaaatg
    10681 ttatactatt agacgatatg atagatacag caggaacaat agttaatgct gcaaatgcac
    10741 ttaaagagtt tggagcaaaa gatgtttatg cttgttgtac tcatggtgtg ttatcaggtc
    10801 cagctattga aagaattgct aattcagaaa taagtgagtt aatagttctt gatactatac
    10861 aacttcctga agagaaaaga atagataaga taaagataaa aacagtagct cctttatttg
    10921 gagatgctat aagaatgata ttctctaatg aatcagtaag taaattattc taatttattg
    10981 tatttatgag agttgtttaa aaggatataa accttttgag caactctttt ttgattttat
    11041 aattatggaa tgttattttt ttcttgttag aaaggtatat attattgtaa aaagagatta
    11101 tagtttaaaa ttatgtatat ttaagtaaaa taaacttaat aaagggcata ttattcaaaa
    11161 tattatgaat ataaaaaata ttacaaaaaa gtattgaaaa aattcagatt atgtagtatt
    11221 atgtaaatat aaataaagaa agaggtgttt ccaatgggaa ggttagaaga tgaaccccta
    11281 ataattaaat gattcagtca caatctaaag tgaatataaa aatctattga aagtttattt
    11341 ataagaattg aaaatagtat ctattctatc tttagtgttt gtgagagggt tctggattat
    11401 ataagattac tgtaaagagt aattttgcac aataagcata tctgtaaatg aagagtttcg
    11461 tttatataat gattgtggct gaatcataac tataatagat agaatgttta taatagatga
    11521 ttttataaaa tactatattg taatagcttt tagctttcaa ataaatatta gcaaaggatg
    11581 gaaatgacaa tgataaaact aaatgataat ttataaatat ctccttacga tatataataa
    11641 ttgtagggag atgtttcttt tttttgtaga gtataatttt tctagaaatt ctgtttcaat
    11701 atgtaaaaag ttggtatata taaatagtat aaacagtgtt gctaaaatat ggtagatatt
    11761 atataatata agtggatatg tatatacatt atgagttata taatttgaat ttaataaaat
    11821 agaaacgttg atttatgttc tgtaatgtgg gcaccttgga gcatattgag ttagtggtgc
    11881 aaccggctat gaaattgtat ttatttataa atactattat tttcatagct ttttttattt
    11941 aaaaaatggt tatatgttag aaataaattt ggttagtacg tttaaataat tttacttaga
    12001 tttttaacca gatatattgt aagtaagtat taattaaaaa atttaagggg gaataaaaat
    12061 gaagttaaaa aagaataaaa aaggttttac tttagtggaa ttattggtag taattgcaat
    12121 tataggtata ttagcagtag tggcagttcc agctttattt agtaatataa acaaggctaa
    12181 ggtagcaagt gttgagtctg attatagctc agttaagagt gcagcattat cttattattc
    12241 agatactaat aagataccag ttacaacaac tgataaagct ggtttaacta ttttagagac
    12301 ttatatggag tctttgcctg ataaagctga tataggtgga aaatataaat tgattaaagt
    12361 tggtaataaa ttggtattac agataggtac agatactgaa ggagttacat taacagaagc
    12421 acaatcagca aaattattga gtgatatagg taaagataaa atatatacag gtgttacagg
    12481 agataatttt ggagacgaat taacagatac tacaaaaata gataataaag ctctatatat
    12541 agtacttata gataatactg tgatggactc aacaaaataa ttaaaactat atttttataa
    12601 agaatattgt aaatttaatg aaaaatataa tataaaagac aggaagaaaa tcttcctgtt
    12661 tttttatact attttcttta atgttcaatt atgaatgatg atataattga gatagtaaag
    12721 gagtgaaacc tgtggctaaa aaagttagaa taggagacaa actggtcgaa aaaggatata
    12781 taacagaaga acagcttaaa tgggcactat cagaacaaaa aaacagtgga aaaagactag
    12841 gagaatttct agtacaagaa gggcttatag atagtaactt actaataagt gtattaaaag
    12901 aactcttgga tatagaaagt atatttttag aagggacaga aatagacact ttagctacaa
    12961 aaatggttcc agaaaatata tgcaaaagat atactgtatt tccatttaaa attgatggaa
    13021 ataaaatatg tctagccatg tcagacccac aagatagaga agcagttcaa gatgtaaggc
    13081 gtatgtctgg taaagacgta gagatattta tatcaagtac agaagatata aacaaagcaa
    13141 taggtcatgc ttatgcacat tcagaaataa ataaggcaat gactgagtac aacaaaaata
    13201 gaactggtgg agtaagagaa acagtaatac ttgaagaaga tgtaaatgct gctccaatag
    13261 tacgattagt aaataacata ctagaaaatg ctgttagaat ggaagcaagt gatatacata
    13321 tagaacaaag tgaaaattac atgcgtgtta ggtttaggat agatggaatg ttaagagaat
    13381 atatgaggat gaactcagca ccatataagg cagtaatcag ccgtatcaag ataatgtcag
    13441 atataaatat atctgaaaag agaataccac aggatggtag aatctattta aaagtagata
    13501 ataaacccat agattttagg gtttctacaa tgccaactaa cagggatgaa aagatagcta
    13561 tgagagttct tgataagagt aattttatgg ttagtaaaga agtactagga atagacgaac
    13621 atggctctaa gatatatgat gaattgataa acactcctta tggtcttata ttggttgttg
    13681 gccctactgg aagtggtaaa accactacat tgtattcaat gttaaatcaa ctaaatacag
    13741 aaaatagaaa tctattaaca atagaagacc ctatagagta tgaattacct ggtgtaaatc
    13801 aatctcaaat aaatgaaaag gcagggctta ctttcgccag cggacttaga gcttttatgc
    13861 gtcaagaccc agatataata atggttggag agataagaga tactgagaca gcagaaatag
    13921 caattagagc ttctcttaca ggacatttag ttttaagtac attacatgca aatacagcag
    13981 ttggagcaat ttcacgtctt ttagatatgg atgtggaaag ttttttaata acttcatctg
    14041 ttttaggtgt aatatctcaa agacttacac gaaaaatatg tgagcattgt aaggtttcat
    14101 atgaagcaga tattggagaa aaaaaggctc ttggtattga tgtaaatgaa tcagtaacta
    14161 tttatagagg aaaaggttgt gaaaggtgta ataatactgg atataaagga cgtctaggta
    14221 tatttgaaat gcttgaaatt actccagaaa taaaagagtt aatagattca tctgcaaatc
    14281 aaagagaaat tttaaagatg gctagaaaac aaggtatggt tagcttaaaa gaggatatag
    14341 ttaaaaaagt tttaaatgga aagacaacag tagaagaaat gattagaata attttgatga
    14401 ctgattaaag gatgatatta tgaaaagttt taaatacaca gtaataaaag aggacggaaa
    14461 aaagcaaact gatgtgattg aagccaacga ttttaatgaa gctagaaatc ttcttagaaa
    14521 gagaaatctt agagttattg aaatcaaaga aagcaaaaat aaaaatataa gattatctag
    14581 tagaaagaga aaaaaagact taggagctga ccagataagc cacttttgta gacagtttgc
    14641 tattatagta tcttctggta taaatagtat ttctggatta gaaacattag ctagaaggtc
    14701 aactaacatt acattaagag aagaaattaa tcgtatagtg gcagaaataa aagtaggttc
    14761 tactattgca gattcaatgc tttcatcaaa atcaaagttt ccaaagttac ttggtgctat
    14821 ggtagctaca ggtgaagcta caggtaaatt agatgaagta ttaaaaagta tggcttcatt
    14881 ttatgcaagt gaacacaggg ttaaacaaaa gcttagaaat gctgcaacat atccattaat
    14941 agttttgatt tcttcattta taatgatttt tatatttaca acatttatgg tgcctaagat
    15001 gattaattca attacaacag taggagcaac tcttccactt ataacaagaa ttgttatggg
    15061 gtttggtatg tttatgaaga agttttggat aatagtactt ttagttatta tattatttat
    15121 ctatcagttt aaaaaatatc taaaaacgtc agttggaagg gctcataaag atagagttat
    15181 aaataagata cctgttttag gaaaaggaat aaattgtatg gtagctacac gattttcaag
    15241 agcattgtat ctatttgtat caacaggata cccattagtt caagggcttg attatattat
    15301 agatagtgta aataacacca tggcagagaa gattttagca tcagctaaag atggaataac
    15361 aagaggagaa ggcttagcag aaaatttaga gagatatacg tattttgact ctgtgttggt
    15421 acagatgata gctatagggg agcagacagg ggaattagag aatataagta gacagatggc
    15481 agaattttat gagtatgaat ccgagattta tttaaatagg atggcctcaa tgatagagcc
    15541 tgttttaata attgcagttg gtattatagt tgcgatactg gttgtatcaa tattcatgcc
    15601 aatgcttagt atatatgatg ccatgtagga gggaaaggac aaatgaacaa ggtttatgta
    15661 tcatattatg gcgattctat ttccatagtt gagggcagat ataaacacga taaggataag
    15721 ttttatgtaa aaaattttaa tgtgttttca atagaggata ttgcacaaga tttttctaag
    15781 gaaaagtatg ctctattgag atacgcatta gaaaatgtta agttaaaatc aagacatgta
    15841 gttttttgtt taaatacaag agatgtaatt ttaaaacccc aaaaacttcc taatatggac
    15901 aaaaaggatt tagacggatt tatgaagcta gagatggacg aaatgatggc tttggagtca
    15961 gatgaatatg tattttcgta tgaagtatct agtgaaacac ctgataattc agatggcgat
    16021 gaatcaagtt taaatcttat tattggagct atacaaaagg aagaggtaaa tgcaattgta
    16081 gagataatgc atgaatttga tttagtatta gatagaatag atacattatc aacagcttac
    16141 ttaagaatgc ttaaaaattt agactacaat gatataatgg taaccaatat aagtgacaat
    16201 agcacaatta taaatatata taagaaagat actttattta ttagtgataa tatacctata
    16261 aagataactg ctaaagatat ggacatgcaa ttattaaatg tagtagaaga atcaaaaggt
    16321 cttatgaatt actattcgtc aagaaacttt ggtaaggtta cggatactat attaatatta
    16381 ggaaaaagat attccaataa attaatttat gaaactttta gctctgcatt ttcaagctat
    16441 gtttctcaag gccttactga gataatggat atatctgata tgataactgg agatatagat
    16501 gaagatgata taaattcaat tgtagagctt ttaggaagta tgatagaacc taaagggaaa
    16561 agagattttg aaaatataaa ctttttacca atggatatac ttagaaaaca gataaaagct
    16621 aaacaaatga aaaacatact gaaaattgct ccaatagtta ttttgattct tgctatacct
    16681 tatttatgtt taattttttc aaataattta gcaaataagg aacttgaaaa tgttaatggt
    16741 gaaataagaa atattgaatc tgcatattat cagattggaa atatagaaaa aatgatacag
    16801 agtaaaagcg aagaaataaa ggtatatgat atgttaattg ggaaaaaggt aaagtgggaa
    16861 aatttattgg atgatataga taaaaatact ccaagtaaag ttgaactaac aagtttatca
    16921 acaacttatc aaaatcttgg aactaataat aaagctgata attcaaaaag taataagact
    16981 acaacagata aatcaagtaa caatgaaaca aaatcaagta cgaaaagtga tagtaatgga
    17041 gataaaacag ataatgattt aaatgaagat aagactacaa atgtgtcaga agcattaact
    17101 ggaaatagtg agactaatag taataacaca gataaagatg ataaaactcc attgtatgat
    17161 aagataccaa atgttataaa tatagaagga aatgctaaag attcctctta tgtaggtcaa
    17221 tttttatata aattaaaggg attatactat ttcaaggatg ttaaattaca tagcataaaa
    17281 agtaatgcag aagattctaa ctatacattt agtatgacat tatacctgaa agaaggtgta
    17341 ttaactaatg aataaagata tatttaaaaa agatataaaa gatatattta aaatggaagt
    17401 tagtctaaaa gggattctta taaaggttat aattttatta gctattttat catatggtta
    17461 ttttggactt taccctcaat atcagaaata tattgctaca aaaaattctg taaaacaggc
    17521 tactgaaaaa ttaaatatat ataaagagaa aactgcactt atgccaaaat atgaaaaaca
    17581 acttgaagaa gttgaaagtg aattaaaaga aaaaagcaaa aatcttttat atgatatgca
    17641 agatggtctt tttttaatag gtttagataa aaaaatgaag gcttataata ttgacttaac
    17701 cagttatgac gttggaaatg ttaaagaata cgaacatttt tatggtatat caacaacaat
    17761 aagtgttaga ggtgattata gaaatgtcaa aaaattaatg gcttatttag aagaacaaaa
    17821 aaatgttact caaatactag attatacaat gacttcatat atagaaccag aaaaagaaga
    17881 ggaagaaaca acaaacaata aggatttaat taaaaatgtg aacataaata aagatacaaa
    17941 aatatactgg gtggaaggcg aaaataagtg gcatttatat aaggattgtc cattgataaa
    18001 agagggagag attctaaaaa atgacaaact tttagatagg tctactaatt atctatgtaa
    18061 tacttgtgta cttagagctg caacagaaaa agaagcaaaa aaagaagtcg tagctccaaa
    18121 ggcagaaggt gtagtagatg ctacatttaa atttataatg tacactaaag agaatactac
    18181 aatgatactt gatacagata atccatcttc atggagacca ggaaaatata atccatttaa
    18241 gtctagtgcg aaataaagct aagtaagctt taaagatagg tgatgagttt gtacaaaaat
    18301 aatgaaaaag gtcttacttt attagaagta ataatagctg tttttatact gacaatagtt
    18361 ttaagtattt cttataaagt gttcaatggt ataacatcag cagtaaaaaa gcaacagatt
    18421 attacagatg ctcaagtaaa tattaatcta attaataagt atctaaatag agatttggaa
    18481 aactgtaaag aactaactaa aactggttca ggtaataatt atgaatacaa tatagagatg
    18541 ccagataatg ttgtaaaata tgaagtttct atagaaacta aaaaaaatac agaggtatat
    18601 tctgtaacga gaatccaaaa caatacaatt gatacagaaa atgaagttag agaagagata
    18661 atctataatc aaccactagt tcaaaacaat aaagaaatga aggaaacacc atttaaaata
    18721 gaaaagcaaa ctggtaaatc tatttatact gtaagtatat actataatga atcagtgcaa
    18781 gaaagtcata aaaatagcaa tttaaataac aaaacttata catttgatgt tatgtcaaga
    18841 ataggataat aagaatttat taaaaaataa gtaggttgat aaaatatgag taaaaagaat
    18901 agtgaaagag gattttcctt aattgaagtg ttagtagcta tggctattat gggaattgta
    18961 ctatttgcat tttttaatat tatcaatact aataacaaag caaacactaa aaatgacaca
    19021 gatataactt ccttaaacta tgtccaaagt gaaatagaaa atctaagaga aaagataaaa
    19081 agtggagaat ttgattttga tagtttagat aaactagaag atggaactgt cgtatatgaa
    19141 aaattaatag ataaatcaaa aaaagttgta tatgataaag ttcttagtga aggtgatgtg
    19201 agcttatatg atactccata tgaaaagatt acaacaataa aagatgaaga tggtaattta
    19261 atcgacaaag gaaatattac aaataagata aagactattg tagaagataa aagtggtcag
    19321 atatataaaa tagctgtaac tgggaaaagc atgaatgact attcaagtaa aaaagaggtt
    19381 aaaattgtaa ctgaaatatt taaagataaa taattttact tgggggtgag attttgagga
    19441 agtggaataa atttaaaagt gaaagagggg cagctttagt tttagttttg gttgtagtag
    19501 cattgctttc tattgttgga ttgatatttt caaatcagat agctaataga ataaaatcta
    19561 caaagactac taatgaaggt atacaagcaa agtatttagc agagacatgt gtggaaaata
    19621 gtattgataa agcatatgaa aaattgtatg atgagcttga gaaaatggat aatgagttta
    19681 aaagtgaaaa tcaagaaaaa tccatatcta ggtcaaaatt aagagatata tcagatgaag
    19741 attttaataa tcaagatgag gaaaatattg aagcagaaag acttggatat atgaataata
    19801 taaatttcta tttaaataaa gcttcttcag acttggaaaa agctagtatg gaattgaaaa
    19861 agctatatga tttagatatg ttggactata gagacattga atatgtagat gcaaatatta
    19921 tttcacatag agattctatc ttagaaattt gcaagaatta tacttctgga gatattagta
    19981 aaataaatga atatattctg aaagaagata tagactcaac tacattgatt gaggcaaagt
    20041 tagtgaataa tgatattctt ttaaaaatgt ttttagaaga aaataaaatt gaaaatgaac
    20101 atttaaattc agccttttca catacttata aggcattaga taacatttct ttggcgatgc
    20161 aaaatatgat tgagtataga catacgtttc atatagatga gccaaaagta gaagtatcta
    20221 atgggattcc agattctcaa caatattatg aactaataca aaatcctata ataaatagta
    20281 tggagtatat ctggaatagt aaatgggata cattagaaaa actattggaa attttaccaa
    20341 atcaaactca aggatttaat tctttaagag ttcatttgag aaataatgta agaaaatttg
    20401 agaagttaag cgataatata tctagtggta aaaaaaatac agcaaaaaat ttcttaaagt
    20461 ataaagagtt attgtatgaa atatcagacc aatgtaatca actaaaaagt atgtcttatg
    20521 agaaaatacc tgttaaatat gataacatgg ctttgataac aacttttgac tatatacaaa
    20581 atgagctttt agcagagata aaatgcagat taaaagaatt aaaaccacaa gaaattgata
    20641 aaacagaagg tattactata aaaatacctt tttataaggc tgactacgac atgacaaaag
    20701 aaggatggcc taaattaaaa gaaaatggtt caggggcgga gttaagctta atggtaactg
    20761 gtgataaaga tggaataaaa gaagtagaag ttacagatgg taaaaaaaat attattggtt
    20821 taggtgttga agaaaattca aattcaaagt ataaggttga cgccattgta aactttaatc
    20881 taaatataga tacaaatgta gttggaaatt atgatataaa agataaaatt ttgattaatc
    20941 atgatataag ttcatacaaa aaagtaaact aaatataaga agcaacttag tataaataaa
    21001 taataaaata attttattat ttactactaa aaaaataagt aaactaatag aagatatgga
    21061 gagtaaatat tatgtatatt tatgatttat tagagcaagg tataagacta aacgcatcag
    21121 atatacacat aacagttgga ataaatcctg tagctagagt aaaaggtgga tttgtaaaac
    21181 taagtgaaca aatattgaca tcagaagtaa caatgcaaat ggcaaaagac atagcagggg
    21241 aatctatgtt taaagtaata gaagaacatg gagaagctga tttttcagct tctttaaaaa
    21301 caggagaaag atttagggta aatgcatata ggcaaaaagg aaattacgca atagcaataa
    21361 ggactataac agcagaaatt ccaacatttg aaaaattagg ccttccagag agtataaaat
    21421 cttttactga aaagcataaa ggattagttt tagttacagg tccaacagga agtggtaaaa
    21481 gtacaacact tgcaagtatg ataaatataa taaatgaaaa acaacaaaaa catataatta
    21541 cacttgaaga cccgatagaa tatgtacatc atcataaaca aagtttagta aatcaaagag
    21601 aagtaggaac tgatacagaa agttttcatt cagcccttag agctattttg cgtcaggacc
    21661 cagatgtaat actaatagga gagatgagag accctgaaac tgtttcaata gcattaacag
    21721 cagcagaaac aggtcattta gtattttcaa cactacatac agtgggggca gctaagacaa
    21781 ttgatagaat agtagacatg tttcaaccat cccaacagca acaaataaaa acacagttat
    21841 ctacagtttg tgaaggtgtg gtatcacagc agttacttcc tacagcagat gggaaaggca
    21901 gaatagcagc aattgaattg atgtttgcta ctccagcaat aaaaaacctg ataagggaag
    21961 gcaaaacata tcaaattcca aacatgatac aaactggagt taaagtaggt atgaaaacta
    22021 tggaccaaga tttaatggaa ctttataaaa atggaaagat tacaaaagat atggcactta
    22081 gtaggtgtac tgaccaagag tttatgacaa gaatgatagg tggagtaaac tacaatggat
    22141 attataatcg ttaatctata tgtatttatg gtgggtatag tgtttggaag tttctttaac
    22201 gtctgtattt ttaggattcc agaaggtata tctatttcta gacctccttc tcattgtatg
    22261 agttgtaata ctagactaaa gccaatagac ttaataccag tgttaagcta tttaatgagt
    22321 ggcagaaagt gtagatattg ttatgagaaa atttctagta gatatgctat agtggaatta
    22381 attacaggac ttttattttt aacagtattt atgttatatg gaatatctac atcaactatt
    22441 tattatttgg ttcttgtgtc tttactgatt ataattacat ttatagatat tgaccacttt
    22501 ataataccag ataaaatatt ggtttttgga gctatatttt ctatgatttt taacctttta
    22561 tttaaagaaa ttccagttaa ggattcaatt ctaggtgttt ttatttgtgg aggaagtgtc
    22621 tggattatag ttcttttgat tgaatttgta ataaaaaaag agtgtatggg tggaggagat
    22681 atcaaactat ttgcaatgct aggtttttac atgggtgtta aaaatggtct tttgacagcc
    22741 ttactaagcg tttatgtggg agcagtctat ggaatctgtg taataattat aagtagaata
    22801 aaaggaaagg aatataattc tgttatacca tatggacctt ttatatctat tggagcatta
    22861 ataacaatct tatgtggaaa gcaattactt gaactttatt tttctatggt tatatagatg
    22921 atagtcaagt taaataaagt tttaatttaa aaaaatgaat taaagtattt aataaggaca
    22981 atattattat taaccctatt actaaagtgc tacaaactat ggagtatata ataataattt
    23041 ccttattttt tgcacatttg ataaataaat ctctatgtgt tttttgtgat agagaaaaga
    23101 aaaatttata caatacgttt tttatttaca taataactgt agttttatct gtattaatat
    23161 atctaaaatt tgggattagt gtagaatgtg tacaatatat ggttttaatt ccatttttaa
    23221 taattatatc cattgtagat tactacacaa tatatgtata tgatataaca atagttagtg
    23281 gtataatagt tcaaggtata atttttttgg tctttttcaa tatagttcaa tttgattata
    23341 taaatcatat atttggacta ttgataggct ttattatacc ttatattatt gctaaactaa
    23401 caaaaggatt aggctatgga gatgtaggtc tctatagctt atgttgcttt gcattgggaa
    23461 ataattatgg gttttatgtg atagttttat catttatttt agcgtttttg ttttttatta
    23521 ttttatacat aactaaaata tttaaagatg tagatataag aaagcaaatt ccttttacac
    23581 cttttatttc cttgtcaaca attttaataa tatttacaga gtataatata tttaattttt
    23641 attataattt gttatacaaa tttatataac aggaggtaag aaatgtacgt agtagtaggg
    23701 ttaggtaatc caggaaagaa gtatgagaag actagacata acgttggatt tgatgttata
    23761 gatattcttg ctaaagaata caatattagt gttactaaaa taaagcataa agctttgatt
    23821 ggtgaaggga gagtaggtac tgaaaaagta ttattagtta aaccacaaac ttatatgaat
    23881 ttaagtggag aaacattaat agatatatat aaatattata aggttgattt aagtaatata
    23941 gtagtagtat atgatgatat agatttagaa gttggaaaga tacgtataag aaaaaaagga
    24001 agtggaggaa ctcataatgg catgaaatct ataactaagt gcctaggttc aaatgacttt
    24061 ccaagagtga gagtaggtgt atctaaacca gaagctggtc aagacttagc agactttgta
    24121 ctttctagat ttagaaaaga agaatctgat aacataaatg aagcattaga aaaagcggca
    24181 gatgctattg actcaataat aagagaaaat atagatatgt ctatgaacaa atataatgga
    24241 tagtgagagg gagatttaaa tgaatgatgt ttttttatat cctttgcaaa attcaaaaga
    24301 gtataaagat ataataaact gtataaaaaa tacaaaaggc tcattattgg ttaatggact
    24361 tttaccagta caaaaacctc atatatcgta ttctatattt aatgatttat cacgacaaat
    24421 gatttttata acaagtagtg atttagaagc aaagaaagta tacgaagatt taagttttta
    24481 tatggaagat aaagttgaat atttaggttt tcaagatatt tatttttatc acttggatgc
    24541 aaaggacaga aacgaagaag cgaagaaatt aaaagtattg ttaaaactag caaataaaga
    24601 aaaaatcatt ttagtaactt ctattgaggc agttttaaga aaatacatac caaaacaagt
    24661 tttgctcgat agtgtatctc attataaggt gggagatagc ttagacttag aaaagttaac
    24721 tgagaaatta gtttcattgg gatatgaaag agtttcaaaa atagaggggt ttggtcaatt
    24781 tagtataaga ggtggaatta ttgatgtatt ttcacttgaa tatacaaatc caattcgtat
    24841 ggaattattt gatgatgaga tagattccat acgaactttt gacgtatatt cacaaaaatc
    24901 aattgataaa ttgcaacaat tctctataac tccatctagg gaatttattt atcccgaaaa
    24961 aactacagat gcattagtta aattaaaaaa agaaacaact aaaaatactg atgaaggtac
    25021 atttcaaaat atagattata tatcaagtaa gacttatttt gaaggtgtag agaactatat
    25081 agattatatt tatccagaag aaaacaaaag tatatttact tatttagcag atgatgcaat
    25141 agtatttatt aatgatataa cgagacttaa agaaagatgc gaaaattata taaatgagtt
    25201 tagagaaaat tataaattaa atcttgaaag aggtctggct attaaaaacc aaggtaaatt
    25261 gttatatcac tatacagatt tagagtactt agtaaaagac aagtctgtgg tattaaactc
    25321 gttattgcca aagtctataa ataacttttc tataaaatct ataataaatt ttgaaagtag
    25381 agaagttcct acatttaatg gaaaggtaga tttgcttgta gaagaattaa atcggctgaa
    25441 atataatgga tacaaaataa ttttagcaac aaatacctta gaaagagcaa ataaattagg
    25501 aaaagattta ttggacaaag gcttagaaac gactatttct aaagatagag atattgaaat
    25561 taaatcttca caagttataa ttgtacctgc acacataaac agtggttttc agtataaatc
    25621 tataaagttt gttgttataa cagataacga aatgataggt gtttataaaa gagcgtctaa
    25681 gactagcaat aaaaaagtta aaaaaggaaa gaaaatagaa tcctttttag atttaagtgt
    25741 tggagactat gtagttcatg aaaatagtgg tgtaggtaga tacacaggga ttgaacaaat
    25801 tacagtcaat gctattaaaa aagattatat gaaaatagta tatcaaggtg gagataatct
    25861 atatgtgcca atagaccaga tggacaaagt acaaaaatat attggtgcag aagtagaaaa
    25921 agttaagtta aataagcttg gaacaaatga gtggacgaaa gcaaaagcaa aagttaaaaa
    25981 agaaattgaa gatatgacaa aagacttgat tgagctttat gcaaaacgtg aaaaaataca
    26041 agggtataag ttttcaaaag atacaccttg gcaggcagag tttgaatcgt tgtttccata
    26101 tcaagaaaca gaagaccaat taaaggctat agaagaaact aaaaaagata tggaatcaag
    26161 taaggtaatg gataggctag tatgtggaga tgttggttat ggaaaaacag aggtagctat
    26221 tagaagtatt tttaaagctt gtatggacca aaaacaagtt gctgtattgg ttccaacaac
    26281 aatattggcc caacaacatt ataatacatt caaagagagg tttgaaaatt atcctttgag
    26341 agtagaagtt ttaagtaggt ttaaaacacc aaaacaacaa aaacagatta ttgaagatgc
    26401 taaaaaagga ttagtagata ttttaattgg aacacataga ataatatcca aagatataaa
    26461 tttaccaaac ttaggtcttg tagtcattga tgaagaacaa agatttggag taaaacataa
    26521 agaagcttta aagaaaatta aatctacagt agatgtactt acactttcag caactcctat
    26581 accaagaaca ttacatatgt ctttaagtgg aataagagac atgagtgtta tagaagaacc
    26641 tccacaagaa agacatcctg taataacata tgttacagag agtaaggaaa gcgtaattca
    26701 agatgagata gagagagaat taagtagagg tggacaggta ttttttgtat acaatagagt
    26761 tgaacacatt gaagaaatgg caagtatgat tcaaaaactc gtaccagatg ctagagtggc
    26821 tgttgcacat ggaagaatga cttctaaatc attagaaaat ataatcctag gatttttaaa
    26881 taaagattat gatgtactag tctgtactac aataattgaa actggtatgg acatatcaaa
    26941 tgcaaataca atgattatat atgatgcaga taaaatggga ttggctcaac tttaccaatt
    27001 gagaggtagg gttggaagaa gttcaagaca aggatatgca tatcttttgt atgaaaaaga
    27061 taaaacttta agtgagatag cggagaagag attaaaagct atcagagaat ttacagagtt
    27121 tggttctggt tttaaaatag caatgagaga ccttgaaata agaggagcag gaaatatttt
    27181 aggttctcaa caacatggtc atatggcagt tataggttat gatttgtacg ttaaaatgct
    27241 taatgatgca attaaaaaag tcaaaggtga acctattgtg gaggaaattg atgttgaaat
    27301 agatttaagt gtaaatgcat acattccaga taattatatc aaagatgagt tgattaaaat
    27361 tgaaatgtat aagaaaatag cttctattga aaacaaagaa gacatgttgg atatacaaga
    27421 agaacttgag gatagattct ctgatatacc taaaccagtc cagacacttc ttacaatagc
    27481 ttatataaaa tcgttatgta agatattaaa aatagaaaag ataagacaat taaaagatga
    27541 aatattatta gttccaataa caaagtatag aactaaacag aaaataggtt ataatatagt
    27601 tacagaatta gaagaattat tagaaaagat gtgcaaggta aaataacttg taaatttaag
    27661 aagggatgtt ttaaatttga aaaaagtaat aacattggta atagctatga ttttggtagt
    27721 atctgtgact gcttgcagtt ctagtaaagg agaaactgtg gcaacagttg aaggtacaaa
    27781 gatatcatca gatgaattta aaaaaactat agctctttat aaagattcta tggaacaaac
    27841 ttatggaaaa gatatatggg ataaggaagt tgaaaagggt gtaaaataca aggacaagtt
    27901 taaagattta attcttgacc aacttataac tacagaagta atatattctc aagctaaaaa
    27961 agataactta cttcctaaaa aagaggatgt tgaaaaaagc tttaaagaat taaaagacgc
    28021 tatgggtaaa gatgaaaaat ataaagaaca acttaagaaa ttaggtatag atgatgagtt
    28081 tttaagagac caacaagaga aagatttagc aatgcaaaac tatcaaagta actttgctaa
    28141 aaagactaaa atatcagatg aagaaatgaa aaaatactat gatacacata aagatgaatt
    28201 taaaaaagat gaggtagaag cttctcatat tttattgaaa acagtagatg ataataacaa
    28261 gccactttca gataaggaaa aagctgaagc taagaaaaag gctgaagagg ctcttaaaga
    28321 agttaaatca ggtgaggatt ttgcaaaagt agcaaaaaaa tattcacaag atacttcagc
    28381 aagtgatggt ggtaaattag gattcttttc aaggggtcaa atggttgctg aatttgaaga
    28441 tgctgctttt tctatgaaaa agggtgaagt atctgattta gttgaaactc aatatggata
    28501 ccacataatt aaagtgacag acagaataaa tgagcaaaca tcatttgaag atgctaaaga
    28561 aactataaaa gaccaactgt tgaaaaataa atatcaagaa caaatagaaa aattaactaa
    28621 agaagctaag gtagaaaaag atgaaaaagt aataaataaa atcacaatct aagacttaaa
    28681 aaaagagtaa tatgcttaaa aaagctatat ctggataaga tatagctttt tttgtatatt
    28741 tttcttaaca atggtaaaaa taaacttaaa gtaatttatg gagggattaa aaaatatgaa
    28801 agcaacaggt atagttagaa gaatagatga tcttggaagg gtagttatcc caaaagagat
    28861 aagaaagaca ttaagaatta gagaaggaga ccctttagag atattcacag caaaagatgg
    28921 agaagtcata cttaaaaaat actctccaat aggtgaatta aatgaatttt cgcaagaata
    28981 tgctgaaaca ttagctgaag tactaggata tggagtgttg ataacagact tagattctat
    29041 aatagctgta tctaagcttc ctaaaaaaga ttataaagaa aaaagtataa gtgatgagtt
    29101 agaagcaata ataagtgaaa gaacagtaaa atattcaaaa gataaaaaca ttttaccatt
    29161 attcaaggaa gaccaaaaag aatatactag tcaagttatc atgcctataa ttagtgcatc
    29221 tggtgactgt ataggttcaa ttgtagttgt ttcaaaggat aaagatacaa ttgcagaaag
    29281 tgaagaaaaa tctttaaaaa ttgctgctaa ctttttagga aaacaagttc aataatttta
    29341 tcataaagac cttttacatg aaggtctttt gaagtttttg tgtaaaatat tgaatatagc
    29401 attaaaaata tggtatatta aagtttgtta tataaacagt atggaggtta tgttatgaac
    29461 aataacaaaa ataaagactc ctttctaaaa ggagccctta tacttgggct agcaggtgta
    29521 atcgtaaaaa taatgggtgg attttttagg attccccttg gaaacatgat tggttcagaa
    29581 ggaatgggat actatcaggc tgcttatcct gtgtatactc tatttttaac attagctact
    29641 gctggatttc caacagctgt ggcaaaattg gtttcggaaa aagttgcaat tggaaatttt
    29701 aaaggtgcaa ataagatatt taaggtatca catacagttt tattcattac cggtataata
    29761 tcattttgta tattattttt tggagccgac tacatagtaa caaacgtaat gaaaaatcca
    29821 ggtgcgttat actctatgaa agccattgct ccagcattac tatttgttcc tgcaatgtct
    29881 gcatatagag gatattttca agggagacaa gatatgacta agattgctgt gtctcaagtt
    29941 gcagagcaat tttttagagt tgtattaggt cttactttgg cctacttgct tatgaagagt
    30001 ctaggtcaga cttttggtgc agcaggtgct atatcagggg ctacaatagg ttcaatagca
    30061 tctatgcttt atttggtgtt tgcttatatg ctagggagaa aagagcgtag agcagagata
    30121 gatgcaagcc aaagatttaa agatgaaaga gtgtcttata tttttaaaaa gcttttaact
    30181 gttgccattc ctataacaat aggagcatca gtaatgccac ttgtaaatat gatagataat
    30241 gttattgtaa taagaagact tatggaagca ggatttacat acaaagtggc aaattcaatg
    30301 tttggtcaat taacaggtat ggcaatggcc acaataaatt taccagcagt cataacaact
    30361 gcaatgagta tgagcttagt tccagcaatt tctaaagcat atgcattagg aaataagtca
    30421 aaagctagaa aagatactaa gagtgcagtt aaggtaactt tacttatagt attgccttgt
    30481 gcgtttggta tggcttcttt agcaatacca ataatgggtc ttttatttcc acatgaacca
    30541 tcttctgtag gaactatttt gtttactctt actccatgtg tattattttt aggattaata
    30601 cagacattga ctggtataat tcagggaatg ggaaaaccaa tagtacctgt aattgcttta
    30661 tgtgttggta tgctatgtaa aattgtaata agttatactt taacaggtat accagatatt
    30721 aatgtactgg gttcagcatt tggtacagtt acagcatact ttgtggcagc catgattaac
    30781 ttactatatg ttaaaaaaca catgaatgta aacttttcta aaaaagaatt tataataaag
    30841 ccatttataa cagttatgac aatgtttata atggttaagt tgagttatgg tgctttagtt
    30901 ggattcttag gaaacagcat atctacaata attgcaatat gtgttggtgg aattgtatat
    30961 gtagtagtaa tacttggaat aggtggaatt aaaaaagaag agattctaac tatgccaaaa
    31021 ggtgataaat tatataaatt gttaaaaaaa gttaaactta taagataata taggaatata
    31081 tatgcaaata aaggaaatac tatacaaata gtaaatctcc ttatttgtat aataatataa
    31141 aaataaagtg aaatttgcta ataggagtga tgttatgggt aagataagta ttgtaggtct
    31201 tggaccagga gactattctc ttataagcca aggtgtgtta gaatctttaa taaatagccc
    31261 taaagttttt tttagaacag agaaacatcc aataattgat aaacttaaag aaactataca
    31321 atacacttct ttagactact tttatgaaaa agaggaaaat tttgataatg tttatttgaa
    31381 aatatctgaa tttatcatag aagaatcagc aaagggtgac ctagtgtatg ctgttcctgg
    31441 tcatccaaga gttgcagaga agactgtaag tataatagag agattagcca atgaaaagca
    31501 catagcagta gaaatattgc cttctatgag ctttgtagac gctatgttta actatttggc
    31561 tatagaccca tctgagggat ttaaactggt agatgctttt gaaatagaaa attcatatat
    31621 agacttggat acaagtatga taataactca ggtatatgat aaatttatag catctaatgt
    31681 aaagttaaaa cttatggaac attatgacta taatcaagaa gtatgtatag taaatggagc
    31741 tggtgtcaaa gatttagaaa gtaaaaagtt tataaagctt tgtgaattag acagaaatga
    31801 aaactttttt gactatttaa ctagcttata tatacccaaa agttctaaaa agatgtataa
    31861 tacagtacat gacttagaaa taatagttaa tacacttaga agtccatctg gatgtgaatg
    31921 ggataaaaaa caaacacatc aatcattaaa aaattctgtt atagaggaag catatgaact
    31981 ttgtaatgca attgataata atgatataga tgaaatggta gaagagttag gtgatgttct
    32041 tttacaggtt atattccatt gtcagatagg aaatgaggag ggctactttg atttaaaaga
    32101 agtagtaaat ggcatatgta aaaaattaat tcatagacat cctcatatat ttagtggtgc
    32161 aaaattagat atgtctaagt ttgagaaaac ttgggaagaa ttaaagaaag aagagaaagg
    32221 cgaaagtact ataacagatg gccttagaag gataccaaaa catttaccag ctcttatgaa
    32281 ggctagtaaa gttcaacata aagcagcact tgtcggcttt gattgggaca atgtagaaga
    32341 tgtatttaaa aaaattgaag aagaatatca ggaattactt gacgaacaca gggtcgggaa
    32401 tataaaatac ataaaggaag agctaggcga tttattattt tcgatagtaa atctagctag
    32461 atttttagac atagactcag gagaagcctt gaactgtact acagaaaaat tcataaatag
    32521 atttgacttt atagaaaaga gtgcaatgaa cttgaataaa aaattagaag acatgacact
    32581 tgaagagatg gatgagtttt ggaatcaggc taaaaaacaa taaaattgtg gaaggaaatt
    32641 tgtcaaaaat ctagaacttt tatcacaaag atagaagtct atattataaa catttttagg
    32701 aggtaaatat cgtgaataaa gctgaattag tatcaaagat ggcagaaaaa agtggattaa
    32761 caaagaagga agcagaagct gcgttaaacg catttatgag ttctgttcaa gatgcactag
    32821 taaataatga aaaagttcaa ttagttggat ttggaacatt tgagacaaga gaaagagctg
    32881 ctagacaagg aagaaatcca agagatccag agcaagttat agatatacca gcttctaaag
    32941 caccagtttt caaagctgga aaaggattaa aggatataat aaatggataa ttagaaatct
    33001 tgtgaaaaag tgtggataaa tttgccacac tttttctata gaaccaagga aggtgataat
    33061 tatgagatta gataaatttt taaaagtatc taggattata aaaagaagaa ctgttgctaa
    33121 agatgcatgt gataaaggga ttgtcactat aaatggaaaa gttgctaaat cttcttcaga
    33181 ggtgaatatt ggagatacat tagaaataca atttggagag aagaagatga agtttaagat
    33241 aaatgaagta aaagagcatg tattaaaaaa tgatgcaaaa gaaatgtacg aaattttaga
    33301 ataaaattaa tagtcctcta gtatattaat agtagtatta ttgaaatatt tactgggggg
    33361 atattatgga acagaacata actttgaaag atagatcaaa gctggttatt tcgggagtcg
    33421 agcacatata ctcttttaat gacaaaagag tagagctcaa aacttctgta ggcgagatgg
    33481 taattgaagg cgaaaaccta gatatgagca agctaagtat agacgaaaat ataattagca
    33541 tagatggaac tataaattct atggtatatg caaagcctaa aaagccacaa gagagtttct
    33601 tgaaaaaggt atttagatag atgatacctt ttactcaaga tgtaagcatt ttttatgcta
    33661 ctatttatgg tggaatactc ataggggtgt tgtttgattt ttatagaggg ctaagaggga
    33721 attttaaatt catcaattat tttgctataa tctttgatgt attgttttgg tttctagcta
    33781 cggttataat attcgtaaca ataaacctta cagaattttt tgatttaaga tattatcatt
    33841 ttgtggcttt gtttattggt tttattttat actataacac cataagtaaa attgttttat
    33901 caattatcaa taaaataatt cgttttgtga gaaattcttt taaaaaagtt acacactaca
    33961 tagtcagttt tttaaataat ttgtattacg ttataatcta ttcactacac ctactatttg
    34021 atattatatt ttatatacca aacatattta tagcaacaag aaaaagtata aaaagaaaat
    34081 caaataaaaa attaaagaac aagaaaaaat caaaacctaa gaagaaaaaa aataaaacta
    34141 aaaaaagggt gtaggaaaaa tgaacttaag aaaaaaattt tcaggacaga ttattgttat
    34201 cagtttattt ttaggaatat caatttttag tatgatgaca ggatttgtat ttgagtatac
    34261 aaaagctaag gaatataaaa aagaaatagc aagtctaaat aaacaattaa aaaagactga
    34321 aatacaaata aacagcttaa agaaagatga aaaatcatat gaaggagact tagaggatat
    34381 agcaagaaaa agattgaata tggtaaaacc aaatgaaaca gtttatgtag acataaatcg
    34441 ttgattaaaa cttgctaata agtttacaga tgtattgatt ttaaaattta agatttaata
    34501 aaaaagtcat tcagttaagg atggcttttt gtttttattg aggagggaat ttcataatga
    34561 aagtaggagc tatagatatt gggacaaact caatgagatt attgatagca gattatagag
    34621 atgggaattt tataaacaga aaaaaatttg ttaatacaac tagaattggt tatggtgtgg
    34681 atagtaaagg atatataaaa gaagatgcta tcaaaagaaa tataaaagca ttaaaagaat
    34741 tttctgataa gtgtaatgat gaaaagtgtg aaaaaattta ttgtatgggg acatctgctc
    34801 ttagagacag taaaaatgga gattactttg ttaaattagc taaagaagaa actggaatag
    34861 atgttgatat agttacggga atagaagaat caaatttggg ctttaagggt gttttagaag
    34921 gaatacaagg tgatgatact attattgtta tagatattgg aggaggttca acagaattta
    34981 ttgtaggtga ttcagaagga attaagttta ataaaagtga gaatgtaggt gctcttagga
    35041 tgacagagag gtttttgaag cacgatatta ttgaagatga agagtttgaa gctatgagtt
    35101 catttatata tgatgagatt gacaaaacgt taaatcatat aaaagacaga ggattaaaaa
    35161 ctcttatagg tataggaggt acgattacat cattatcagc aatgaatcaa gaattagaga
    35221 tttactctat ggaaaaaata cataatagta aaatacacaa aaaagaaata gaagaaattc
    35281 tacaaaaatt aataaagatg acattaagtg ataaaaagaa cttaaaaggg ctacaagaaa
    35341 aacgtgcgga tattataact gctggtgtaa aaatattgaa tataataatg gaaaaattag
    35401 aaatagaaga aataaccgta agtgaatacg ataatttgga aggcttaata tgtcaaaagt
    35461 caaaaaaaat gtattaatat tttttgattt ttaaaaccga ttatgacaaa aaaaattact
    35521 cctctttgtt acaattctta atataaacaa aagaggaggt ttttttatgc aaagaagtgt
    35581 agcagttgtg aagaataaga ctgtaaaacc aaatgtcata aaattaataa gcggatatat
    35641 tgattttact acggcggcat tcgctgtgat gggattttta cttagtaggt ctattatagt
    35701 agactctgta gctcctttag gaattgcctt ttttatatgt gcatcaaaga ttgataagta
    35761 caagatacct gtattcatat caacattatt aggaatattg ttatcatcta atgattttgg
    35821 aaatgtagca aaatatgctg tgtgccttac aatatttatg gctatgaata aaaaattaaa
    35881 attatcagat tcaattgcta aggttgcatt tataggtgca ataatactac ttccaatctc
    35941 catgggacaa gctttctttt caaataggta tgtatatggt cttcttatag caggagtaga
    36001 atcaataata atgtttatat ctatatatgt gttttcttat gggataggtt taatggccaa
    36061 tgtcaacaat aggatgtctg tacggacaga agaagccata tcaataagtt tactgctaac
    36121 ctttagcata atgggaatag gagatatatc tctgtttgga atatcaataa ggaccatttt
    36181 atcgaccgta ttgatattgc tgacctcaat agtaggtgga gctaccatgg gagcatctag
    36241 tggtgtaatt attggtgtag catccatttt aaataatatg acatcagctg tttatatggg
    36301 gatatattct ttttcaggat taataagtgg agcatttaat aaaataaata aatatttctg
    36361 tatactagga tatattctaa gttggacaat aatataccta tatacttctg gtattacttc
    36421 taatatgatg caattaagag atatactatt aggttgtttg atagtactag tattgccaga
    36481 gcgattattt aataagattg aaaaattaat aaaaagtaat gtggcttcaa atgaaatcgt
    36541 atacgattat attatgagaa gcaaaaacct aactaatagc agattgaaca gtatttataa
    36601 aacttatgat gaccttgcag atacatttga taagataaga gaaaaagaca aagtgctaga
    36661 ccaaagagac atagctaatg taatagatat gattcataat gatgaatgta aaagttgtag
    36721 tatgagaaga atgtgctggg agtcaagatt taatcataca tacactatga tatataacat
    36781 tcttgaaaaa attgaggaga aaggggagtt aagtctaaac gatataccta aaaattttag
    36841 aaaggaatgt atgaaaccag agtcaatagt gaaaatatca aatcactatt acaaaatgtt
    36901 tgtattagat tatgattgga gtgtgaagtt ttcagaaagt agaaagttaa tagcaaatca
    36961 gataagaagt atttcaaaat ccattaaatc cttatctcaa gatttagaag gcgacataat
    37021 gctagatata gaaaaggaaa aaaatatata tgaacagtta gaaagatatg atataacagt
    37081 tgataaagta agttacttaa caaaaagtaa cagtgagttt gaaatatcaa tagaaaagaa
    37141 aacttgccat gatggatgta tgtgtgaaga taaaattgta aatataattt cagacctagt
    37201 aggggaaaat atgtctgtta gaaaaatagg atgtcactgt ttaggaggta aatgcaaggc
    37261 aacattcgtt aaatctcaaa aatataaggc tgttacagaa gtttcagcaa tgtcaaggga
    37321 tgggcatatc ctttgtggag acaattacac atacatggag ataaatgatg gtaaatacat
    37381 gatggctata agtgatggta tgggaaaagg taaaaaagca tatgaagaat cttctgccac
    37441 tattgatata ctggaaaaaa tgatagatgc aaaaattaaa gatgagatag tcattgatac
    37501 tataaataat atgttgttgt taaagtcttc agaagagatg ttttcaactc tggatttggg
    37561 aattttagat ttaaaacgag gttgtttaga aactataaag atgggagcgt gttctactta
    37621 tataaaaaga gaggatggag aagttgactt aatatcgtca tcatcattac ctgtgggtat
    37681 attatcagat gtaaaaattg atagaaaaaa tgtaaaagtt aaggaaggag actatgttat
    37741 aatggtttct gatggaattg tagatgcagg aagaaataac aatttaggag acaattggtt
    37801 aatatacttc ttaaagaata tagagactac aaatccaaag gaaatttcaa atttaatatt
    37861 ggatagagca ttagagttac aagcgttaca aattgaagat gacatgactg ttttagttac
    37921 gaaaatatgt acaaaataag gtttacaaga ttatgtgtat aagatgtgga taacttgtgt
    37981 ataatatgtt aatagacttt tgaaaaaagt atagttatta acaaaaataa catataaatc
    38041 aacaaaattt gttgataagt atggcagaaa tgttaataaa atgtaaaaaa agaaaaaaca
    38101 aaagctatta tcaaaagaga ttcatgttga aataactaaa tttctaagta aagaaaacct
    38161 gtgaatatgt tgattattat gtggataact attaattcga tatttattta tatagtatga
    38221 ataattgaat aatatatcta aaaaaagcca tcctattatt aagtaaactt attgaaagga
    38281 tggcttttta tgaatagaaa attgtgcaaa gcaataatac ctttatttat ttctattttt
    38341 tgcatgttaa taataagtat aaaagctgac caaggatatc aaaagaataa tgacagagca
    38401 attactgtca tgaataataa tgatactgaa gatgatgctg aaaaaaaaca agaaatagac
    38461 tatgaaaaaa catgttggaa tttgcaatct ttgtttaaaa gtgatgacca atggaaaaaa
    38521 gaacttaaga gttttgataa agatactaaa gagttgaaaa attacatagg taaagtaaca
    38581 aaatcgccaa cacatttgtc ttttgcctta aacattaaag aaaaacttga tataagacta
    38641 aataaacttt ctgcctatgt aaaattaaaa caagatacta ataaaaattc gtataagtac
    38701 ttagatatga atgatagtat gagtaaatcc tatgggaatt atatggggat ttgttcagat
    38761 ttagagttag aaatactaaa attatcaaac aaagattaca agaaaattat ttcaaataaa
    38821 aatataaata ggaaatatgg tgcatattta agagatataa gaaggaataa agtacattat
    38881 ttggatgata aatcagaaga tattctaagc aaagtatctt caataagtag tcttccaagc
    38941 caagtgtatg aattatttag aaatatggat agaaaaacta atttgacacc agctcaatat
    39001 gcgagtgaat tagagtcatc agatagagaa aatagaaaaa aagcttatca agatgaactt
    39061 ataacttaca atgataatat aaatacaatt gcaggtttaa ttactggtca agttaaaaag
    39121 aatatttttt attctcagga aagaggttat gagtcttctt tagaaatgta cctggaatct
    39181 gataatgtag atgaaaaagt atacaataat ttgataagga ctgtaaatag taatatggac
    39241 agtctacaca aatatataga tttaagaaaa aaagtattaa aattagataa ggttcattca
    39301 tatgatatgt ttgtgcctat ggttaaggct gttgataata atattaatta tgaaaaggca
    39361 caaagtatag tatattcagc gttgtcacct ttaggaaaag aatacaatga tgtagtatat
    39421 aaagctttca atgaaaaatg gatagatgtt tattcacatg aaaataaagt aagtggtgga
    39481 tactgcttat ctgtttatga aaatcatcca tatatacttt taaattataa taattcatta
    39541 ggttcagttt cgactttatc acatgagctt ggacatgctg tatatgaata tttaagttct
    39601 aagaatcaga attattttaa ttcaaatccg tctatattta ctcacgaagt tgcatctaca
    39661 acgaatgaag cattacttta cgagatgctt ataaaagaag ctaaaggcaa tgatgaaaaa
    39721 gcttattata taacacagta tttagacttg ataaaagata ctctttatac acaaactatg
    39781 tatgctgaat ttgaaaaaac tatacacgag ttagtagaaa aaggaaaaag tgtaaacgca
    39841 ttagtattaa atgatgtttg gggacaactt cttaaaaaat attatggaca aagctatgaa
    39901 ttagaccaat tatctaaggt cggatgggct agaatcccac atttttataa tagtttctat
    39961 gtctataaat atgctacagg ttgtagtgca ggagtaagtt ttgcccaaga catcctaaag
    40021 aatggttcag ataactatat gagctttctt aaaaagggaa gttcagatta tccaataaac
    40081 ttgttaaaat caagtggcat aaatttaact aatacaaaac ccatagaaaa tacaatcaaa
    40141 aaatttgata gtttagtagc agaacttgaa aagctattat aaacattatt gtaatccaca
    40201 tggtaaatat atcgaattaa tgataaaata tactaaaagt ttaaagtcct atcaagatag
    40261 gactttttat ttattaatta gtgggagatg attctatgca agttaaagtt aaaaaggctg
    40321 taataccagc agcaggttta ggaactagat ttttgccagc tacaaaggca caaccaaaag
    40381 agatgttacc aatagttgat aagccaactc tacaatacat aatagaagaa gctgtggcct
    40441 caggaataga ggaaatacta ataataacag gtagaaataa aaaatctatt gaagaccact
    40501 ttgataaatc tgtagaattg gaacttgatt tagagaaaaa aggtaagaaa gaattgttgg
    40561 aggtagtaca aaacatatct aacatgatta acatacatta tataagacaa aaagagccaa
    40621 aagggttggg agatgcaatt tattgtgcga ggcattttat aggtgatgag ccgtttgcag
    40681 taatgttagg ggatgatatt gtagataatg atgtaccttg tctaaaacaa ctaacagatg
    40741 catatgagga atatagaact acaatattgg gtgttcaaaa ggtaaatcaa gaagatacta
    40801 ataaatatgg gataatagaa gcaaaaaata tagaaggtag agtttacaag gtaaaagaca
    40861 tggtagaaaa gccagagtca ggaaaagctc cttcaaatat tgctatttta ggtagatata
    40921 taataactcc tgaaatcttt gatattctta aggatttacc accaggtaaa ggtggagagg
    40981 tacaacttac agatgcttta aaaatattat ctaagaaaga agctatgtat gcatacaatt
    41041 ttgaaggcaa gagatatgat gttggggaca agctaggatt tttagaagct actgttgact
    41101 ttgctctaaa gaaagaagac cttaaggaag attttataaa atatttgaaa catgtatgta
    41161 gtgaatttga taaaaataac aatgtgttat acaataatac agatgaaaaa atagatttaa
    41221 ttgaagtcaa tgaagctaga gaacttgaaa ttcaaaaata attaatgaaa ggtgatgtat
    41281 ggtggcaaaa tcaagtcaga aaaaaattaa tagaataata gctgttggga ttgtgggaat
    41341 cctcgtaata acgagtataa cagctgtttt gagtatgatt gcaactatgt aataagataa
    41401 atgacagcag ttgatataca taaatataaa aaccatatat aacttgatgt agtcaaaaac
    41461 ttacaatatt ttagttatat atggttttta gaatttataa atgtaaaaaa aaatttttat
    41521 aatagttgca tattttaaag gaaaatatta ttataagata taaatatagt gataaattta
    41581 taaaaacgtg ctaagattgg acttgaaata cagtaatata gtaggtaata atgttttaaa
    41641 ttttatttat tgaccataat atataaataa tgatattatt agacttaact gtttaaataa
    41701 aacttttctt tttcatgcct tcaatttcca aaataagtat gtatataaat gaatatatag
    41761 atgaggagga tttttttgat tttagatgat aaagtattag aaggattagg tagtaagacc
    41821 ttagttgagc tacgagagat agctaaagaa ttaaaaataa aatcaattac tacatataag
    41881 aaaaatgagt taattgagat tataaattcc aaaagtaaaa atgaggaaaa agtaaacgaa
    41941 gagactaaag aaaaaaatga agatattaaa gaagacataa agaatagaaa agaaaatata
    42001 gagcgtgaaa gtatagaaaa agaagttgaa tataagagcc ctaccaaatc atacaacaag
    42061 aaagaaatag atacccaaaa tatttcccaa aaccaagaac atagaaatca aagaaatgac
    42121 tataataaga caacgagtgt aaatgatagc aataagtcat caaatatatc taatagaatg
    42181 gtcagaaata ataataaaaa ctattatatg cctaaacaag ttgatgaatc taagatagta
    42241 gatgaattta acacatcaaa agaggatgaa gtagtaggtg tacttgaaat tctgccagat
    42301 ggatttggtt ttttaagagg ttcaaattat ttgtctactg aaggagatgt ttacgtttca
    42361 ccatctcaaa taagaagatt taatatgaaa acaggagaca agattaaggg aataactaga
    42421 catccaaaaa gtggagagaa atttagagca cttttatatg ttcaaaaaat aaatgatgaa
    42481 aaccctgaca cagctataca aagaaatgcg tttgagacat taacaccaat atttccagaa
    42541 gaacgactta cactggaaac taatagaaat gaaatagcta caagaattat agatttaatt
    42601 tcacctatag gaaaaggaca aagaggattg atagtagcac ctccaaaagc tgggaaaaca
    42661 gttcttttaa aaagcgttgc aaatagcata gctaaaaatc atccaaatgt tgaacttata
    42721 gtactcctta tagatgaaag accagaggaa gttactgata tgaaagaatc tattgaagga
    42781 gacgttatat attccacttt tgaccaagta tcaagtcatc atgtcaaggt tgcagagatg
    42841 gtgttaaata gagctcaaag attagttgaa catggtaaag atgtagtaat tttactagat
    42901 agtataacta gattggcaag ggcatataac cttacaatat ctcctacagg tagaacttta
    42961 tctggaggta ttgaccctgg tgcacttcat ggacctaaaa agttctttgg tgcagcaagg
    43021 aatattagac agggtggttc tttgacaata ttaggaacag cattggttga aactggttct
    43081 aggatggatg atgtaatatt tgaggaattt aaaggtacag gaaatatgga gctacattta
    43141 gatagaaaat tagcagaaaa aagaatattc cctgcaatag atatttacaa gtctggtaca
    43201 agaagagatg atttattgct tgatgatgaa gaaaagactg ctctttggag attaagaaga
    43261 gaaatgagta ataattcagt aatggaaatt acagataaag tcattgaact tataaagaga
    43321 actaaggaca ataaagagtt tgtaaaatca ataaagaatt tgtaaaatca ataatacaaa
    43381 tgcaaatatg gattatataa actaatagaa aaatcacttg aatggcataa taagttgtgc
    43441 tataataatg tagttgataa tgtaaaaaga aagttaatat aattaatttt tttaaataaa
    43501 gagaagaggt gactataatg caaaaggaaa tacaaccaaa atacaatcca gttgaagtgc
    43561 gttgtgcttg tgggaacaca tttgttgctg gttcaactaa ggacgaaata aaagttgaaa
    43621 tatgttcaga gtgccatcca ttctatacag gaaaacaaaa gaacatagaa aaaggtggaa
    43681 gaatcgacaa attcaagaaa agattcaaaa tggactaatt tttataaaag tggagttgga
    43741 ggaagccaac tcctatttta ttacaaaaaa acattcatat tctactttaa attgtctttt
    43801 tgtattataa taataaatat gtaaaattga gtattctaaa tacaataaaa tgaggtgagt
    43861 ggatggcaaa acaagctgta ggtgggcaag ctgttattga aggtgtaatg atgcagtcaa
    43921 aagacaaaag agcggtagct gttagaaaaa gtgacggaga aatagcacta aaagaagata
    43981 gaataaaaag ttgggtaaga gataagaata tagataagat accttttgtt agaggttctt
    44041 ttgttatgat agatacaatg attcaaggca taaaaagctt aaacttttct tcagagtttt
    44101 ttatggaaga agctgaagag gataaatttg atttatttat aaagaaaatt tttaaagata
    44161 aggcaaatga tataattata atattttcat tggtcatagc aatgttactt tctgctggat
    44221 tattcatttt tatacctaca ttggtaggag gagctttttc taaagtaatg cctaatgatt
    44281 ttatgcttaa tttaatagaa ggaatcataa ggatagctat attatttgca tatatagtat
    44341 tgatttcacg aagtaaggat atagaaagag tctttcaata tcatggagca gaacataaat
    44401 ctatatattg ctatgaaaat gatttagaac ttacagtaga gaatgctaga aaatttaaaa
    44461 gattacatcc tagatgtggt acaaatttcc tatttatagt tatggctgta tcaataatat
    44521 tgtttgcatt ttttggttgg ccaaatccaa ttcttagaat atttatgaga attatatgtg
    44581 tgcctatagt agcaggttta tcttatgagg taattagagt tcttgggaaa tatgataatg
    44641 gatttactaa aattattgca tatccaggaa tgatgttgca atattttaca acaaaagagc
    44701 ctgatgatga gcaattagag gttgctttgg aagcattgaa agcagtagta gattagagaa
    44761 aaggatattt gttatgacga taaaagatat aattattaaa tattcagata aactaaaaga
    44821 tctaagtgat actccaagat tagatacaga gttattgtta caaaaaacat tgggtgttga
    44881 tagattatat attcacttaa atctgaataa agagctaact gaagaacaaa aaacaaaatt
    44941 tatgggtttt gcagaagaaa gattaaatgg aagaccaata gcatatatag ttgaaaatag
    45001 ggagtttatg ggattagatt tttttgttaa ggaaggcgta ttgattccaa gaccagatac
    45061 agaaacttta gtagaagaaa taattgaaat atgtagagaa aaaaaagatg taagtatatt
    45121 agatatagga actggttctg gagctattac aataagttta gcaaagtaca ttgaaaattc
    45181 taaaatcatg tcttttgata tatcagagac agcattagaa atagctaaaa aaaatgctat
    45241 tataaatgaa gttggtgaaa aaataaagta tattaattct gatttattta cagcaataag
    45301 tgatagtaac ataaaattcg atatcatagt ttcaaatcca ccatatatta aaaaacaaga
    45361 tatagaaact ctgcacaaac aagttaaaga ttatgaacca tataatgctc ttgaaggtgg
    45421 agaagatgga ttagactttt atagaagaat aacagaacaa ggtaagaaat atttaaataa
    45481 gtgtggaata ttagcatatg aagttggtca taatcaagct gaagatgtaa taaatattat
    45541 gaaaagtaat ggatataaaa aaatatacac aaagaaggat attcaaggca ttgatagagt
    45601 tgttataggt tacaatatat gatataatca acaattgata tgttacattt aatcgaggtg
    45661 aaagtatgtt aaaaaaatta gaggtattgg aagatacata taaagactta agtgaaaaaa
    45721 taggtgatcc ggatgtaata aatgatcaaa aagtttggca gaaatatata aaagaacatg
    45781 ctgacttgga acctattgtt atgaaataca gagagtataa aagcgtttta gatagtataa
    45841 aagaatcaaa agaaatttta caagaagagt cagatgaaga attaagagaa ttagctaaaa
    45901 tggagttagc tgagatggaa gaaaaagtag cacctctgga ggaagaaata aaaatactat
    45961 tattgcctaa agaccctaat gatgataaga acgttatagt tgaaattaga ggtggagctg
    46021 gaggagatga agcagctcta tttgctggtg atttatttag aatgtactca aggtatgctg
    46081 aaagaagaag atggaaaata gaattattga gtgcaagtga tactggagtt ggtggatata
    46141 aagaagtatc ttttatgata aaaggtaaag gtgcttattc aagattaaag tatgaatctg
    46201 gagttcatag agttcaaaga ataccatcaa ctgaatctgg tggaagaata cacacatcaa
    46261 cttctactgt tgcagtatta ccagaagttg aagatgtaga ggttgaaata aatccaaatg
    46321 atttaagaat agatgttttc cgttcttcag gtaatggagg acaaagtgtc aatactactg
    46381 actctgctgt tagggtaaca catataccta caggtgaagt agtatcttgt caagatggaa
    46441 aatcacaatt aaaaaataaa gagcaagctt taaaaatatt aaaagctaga ctttacgata
    46501 aagcattggc agaacaacac aaagatatag cagcagaaag aaaaagccaa gtcggaacag
    46561 gagacaggtc agaaagaata agaacatata atttccctca aggtagaata agtgaccata
    46621 gaataaattt aactttatat aagttagatg cattcttaga tggagatata gatgaaatga
    46681 tagatgcttt aattactgtt gaccaaacag aaaaaatgac tgcaatataa gtaatgtttt
    46741 aaagaagctg tttcttccta gaaattattt tctattttga aacagctatt ttgcatttta
    46801 ggtcatgtta tcatattcta ttgtatataa ttgttatata caagtatagg agggttatat
    46861 gatactaaaa gtaacaataa ttgggctttt ggcaggtgtt atagggacag gattaggagg
    46921 agtaatatca gccattttta aaagagaggt cgataaatat ctaagttttt ttatgggatt
    46981 atctggtgga ataatgttgg ctgtagtggt gtttgattta atgaaagaat ccatggacaa
    47041 aatggggata atcaatacag ttatatttac gtttgttgga gctctcataa ctatgtacat
    47101 aaaaacaaaa ttagatgtgt ctggaaatat ggcatctgga tatcttatat tcataagtat
    47161 attactacat aatttaccag aaggactagc cattggttct tcttttatgt caactgaaag
    47221 tttaggtatt acacttgcta tagttatagg tctacataat ataccagaag ggttagctat
    47281 ggcattaggc ttagtttgca ataaaatgaa actaagtaaa gttattttgt ttactgtaat
    47341 agctggatta cctatgggtc taggaagttt tttaggtgtt tattttggag gagtatttac
    47401 ttctcttata ggagtatttc ttgctacagc aggaggtact atgatgtatg ttgtattgga
    47461 agaaattttt ccacattcaa aaagtgtgta ttgtataatt ggtttcttgt taggtacaat
    47521 gattgtaaat tatatataaa attaaaatga aagcaggcat acaaaagatg aaaactatta
    47581 taagtaatat tgatataaat aatattgatt atgaggaaat aaaaatacaa gcaaaacttc
    47641 ttagagaagg taaaacggtt atttttccaa ctgagacagt atatgggttg ggtgcaaatg
    47701 cattagatga aaatgcagta aagaagattt atgaagctaa aggaagacct agtgataatc
    47761 cattgatagt ccatatatat gaaaaagaag aagtatatga cttagccaaa gatataagtg
    47821 ataaagctaa acttgttata gaaaagcttt ggccaggacc tataacaatt atattaaata
    47881 aaaaagatat aattccatac aaaactagtg gagggcttga tacagttgca ataaggatgc
    47941 cttctaatgt tattgccagg gcaataataa aagaagctgg tatacctatt gcagctcctt
    48001 ctgcaaatat ctcaggtcgc ccatctccaa caaaagcaaa acatgtatat gaagagatga
    48061 atggaagagt ggatggaata gttttaggag gagacagtaa ttttggattg gagtcaactg
    48121 tattggattt aacagaagag actcctatga tactgagacc aggaagtata actaaagaag
    48181 ttttagagga acttcttgga gaagtaaagc ttgacccatc attaagtaaa aaagaagata
    48241 atcaaaaagc taaagctcct ggaatgaaat ataaacatta ttctccaaat gcagatgtat
    48301 atataatatc tggaaaaaga gaaaatgtag caacaaagat taatgatatg ataaaatcta
    48361 atagagacaa aggtctaaag acaggtgtaa tgtgtattag tagaaaccga gagttttatg
    48421 atggagaagt aatcgattta ggaaactctc ttgaagaagt tgcaagtaat ctgtttgatg
    48481 ctcttataga aatggacaaa aagggtgttg atgtcatata ttcagaagag ttccccaaga
    48541 ctggagttgg acaagcaatt atgaatagac tactgaagtc agcaggatac aaagtgataa
    48601 aggcttaaga gggagttgta aaatatgaat atacttattg tgtgtacagg taatacttgt
    48661 agaagcccta tggctgaggc tatactaagg aaagcaatta aagaatctgg aagaagtatt
    48721 gaagaatatt ctatatcatc agcaggtata tctacagcaa atggaatggg tgcttctgaa
    48781 aattctatag aagtactaaa agaaatcggt atagacttat caaatcatag aagtaaagta
    48841 attactaaaa aattaattga tgaatcagat ataatactaa caatgactaa atctcataaa
    48901 gaaattttag tacaagcagt tccaaaatgc aaagaaaaag tgtatacttt taaagggttt
    48961 gcaaataaaa atgaggaaga tatatctgac ccatttggtg gaaatttgga tatttataga
    49021 agcactatga gagaaataat gtattctgtc aacgaaatag taaaaaaaat atgaaacgga
    49081 ggataaacaa atgaagatag gattaggctg tgaccatgga ggatataatt taaaaaaaga
    49141 aataataagc tatttagaaa gtaaaggtat agagtgtgta gattatggaa ctaataatgc
    49201 tacagattct gttgattatc ctgtttatgg agaaatagtt gcaaattcag ttataaataa
    49261 agaagtagat tatggaatat tatgttgtgg tacagggata ggaatatctt tagctgctaa
    49321 taaggttcct gggataagat gtgcagttgt atcagatgta ttttctgcaa aaatgtcaaa
    49381 agcacataat gatgcaaata tgttatcatt aggcgaaaga gttttaggaa aaggtctagc
    49441 acttgagata gttgaagcat ggattaatac ggattttgaa ggtgatagac atgctagaag
    49501 agtaaacatg attaaatcaa tagaagaaaa acataataaa taataaaaat tacagtttta
    49561 tcaggaggaa ttatcaaaat gagcaaagtg gtagagacaa accatccatt aatacaacat
    49621 aaattaactt taatgagaga taaaaatact ggttctaaag actttagaga gcttttaact
    49681 gaaattgcaa tgttaatggg gtatgaaata acaaaagata taccattaaa agatgtagaa
    49741 atagaaactc ctattcaaaa aacatcatct aaagtagttg caggtaaaaa attagcaata
    49801 attccaattt taagagcagg tcttggaatg gtagatggat tagtgagctt aatgccagca
    49861 gcaaaagttg gacatgtagg actatataga gacccagaaa cattaaaacc agttgaatat
    49921 tattgtaagc ttcctcaaga cataggagaa agagatataa tagtagttga ccctatgctt
    49981 gcaacagggg gttctgctgt agcagctata gatttactta agtctaaagg agctaaaagt
    50041 ataaaattag ctaatttagt agctgcacca gaaggtatag cagaagtgca aaaatatcat
    50101 gatgatgttg atatatatgt tgcatcagtt gacgaaagat taaatgaaca tggatatata
    50161 attcctggtc ttggtgatgc tggagataga ttgtttggaa ctaaataaaa ataaataact
    50221 ataaatattt attagggact ttcttatata gtgtatataa ttttatgtaa gaaggttctt
    50281 ttttatatat tttttctcaa aataggaatt attgaattga taaatttctc gaattgagaa
    50341 taaaaagttt ttaccaatta aaaaagattg cttattttac aaggttttat agaatagtag
    50401 tctattttaa tgtggcatgt tagttgctta cgattatagg tattaagtgt attagttaaa
    50461 ttgagaattg aatattaata atattattgg gagtggtaat acatgaagaa ttgtatagta
    50521 gtaagagggg ctggagattt agcaacagca gttattcata aattacacaa cagtggtttt
    50581 aaagtagttg cgttagaaat agaagagcca ttagctataa gaaggcaaat ttctttttgt
    50641 gaggctgttt atgaaaaaaa agtaactgtt gaaggtgtag aatgtatatt ttgcaatact
    50701 gaaaaagaaa tagaggaagt tttatctcaa cataaagtag ccttgattat agacccaaaa
    50761 ggagaaaaat tatctaaatt aaatccaatc gttttggttg atggaatact cgctaagaaa
    50821 aacttaggta caactaaaga tatggcacca cttacaatag ctttaggtcc tggattttgt
    50881 gcaggagaag atgtagatgt tgttatagag acaatgagag gtcataatct aggaagaata
    50941 ataactaatg gtagagcaga aaaaaataca ggagtaccag gagcaataaa aggtttttct
    51001 aaagagagag ttatgcattc acagtatgat ggcataatgg aaaatgtatg taagataggt
    51061 gatatagttg aaaagggaga cctactttgc tatattaata attatgaaaa aaaacatgaa
    51121 gttagagcaa caatatctgg agtccttaga ggtttattaa aggatggagc aaaggtaaac
    51181 aaaaatttaa aaatactaga catagaccct agaaaagaag aagttaagaa tgcttttaca
    51241 atatcagata aagctagatg tatagctgga ggggttttag aagccatact aaacaatggg
    51301 atttatcccc aaaattaatt tatattagat aaagctatta atattttatt aagatgatat
    51361 aataaattta atagattaaa gagagcatat gacgggtatt taaaatttaa atggtaaaaa
    51421 tgctcttttt ttattggaca ttcaattaac atgtgtatat aatataaaaa taagtattta
    51481 tttaggttga aatctaataa atatataata ccagtacata agcaaagagg agaaaagtaa
    51541 attatgagac catcatggga tgaatacttc atggaaattg cagaagtagt gaaaaagcgt
    51601 tcaacttgta ttagaagaca agtaggagct gtaattgtaa gagacaaaca aatattaaca
    51661 actggatata atggttctcc gagaaatctt gaacactgtg aaaatattgg atgtaagagg
    51721 caggaattaa atattccctc aggagaaagg catgaattat gcagagcatt acatgctgaa
    51781 caaaatgcga taatacaagc tgctcataat ggtattagtg tagatggggc aactttgtat
    51841 gttactacaa gaccttgtgt tttgtgtgca aaaatgtgca taaatgcagg tatattgaaa
    51901 attgtttatg aaggtgatta tccagatgat atgtctacag aattattaaa agaagcagga
    51961 atagaactca taaaatttta gtggataaaa tttatatgac aataaatgtc aaattatgac
    52021 actgaaatac aatggtatca aatgattaaa agaaagtatt tgaaaaatca tcagattagt
    52081 agtaagatat attttataat taaataaatt tatgagatag attaattaca tgttatttat
    52141 tttataataa tgagggatac tatttatgag taaaagaaat acacatacag aaattgcaaa
    52201 gttgtttagt ttaataagtc aaataggatt gatgattgta atatcaatat taggatgtac
    52261 tttcttagga aaatttttag atagtaaatt gaatactact ccagttctga caataatatt
    52321 tttattgttg ggtgttggag gtgcttttag tggtgtttat aaaactctaa tagtatatac
    52381 acgaaggaag tgatatattg gatataaaat tacttaacca ggtaaggtca gtaacaaaag
    52441 gtatagtaat atttgatgta gttttaattg tgctaatgtt gataacatca acattaagta
    52501 aaccagtatt attaggactt atatttggct ctataatagc tatgttaaat tttagattat
    52561 tggcgatatc actggaaaaa tcagtgacat ttcctgctgg gaaggcacaa gcttatgcat
    52621 cagcacaata tgctgttaga ttatttataa tggcagttgt tctaattgca tcagctacag
    52681 taccacattt aaatataatc ggaacagcat tgggattatt gagcacaaag tttgtcatat
    52741 tatcaaaaaa ctttataaat aaattaaaga ggaaggaggc ataagtatga atcaagcgca
    52801 ttattatctc ataggaaact ttaagattag tgaaacaata ctagtaagtt ggggaataat
    52861 ggccttttta gcgatagcat cttatttttt gactagaaac ttaaaaaaag ttccaactag
    52921 taaagttcaa atattcttag aatttgcagt aggtggtctt gctaaaatgg ttacagatgt
    52981 tatgggtaaa aatacagtaa aaagaatgcc atatatgata ccatacatag gaagcttgtt
    53041 tttatttttc gcatgttcaa atttaagccc attacttgga ttaaggtcac caacaaccga
    53101 cttagacaca actgctgcat gggcaatgat tacatttttt atgatttatt ttgcaggagt
    53161 taaatttaag gggttatcat actttaaaga attggctcaa ccacttgcca taatgttacc
    53221 aatcaatatt ataggtgagt tagctagacc aatatcatta agtttccgtc catttgggaa
    53281 tattttaggt ggaacaataa taatgggtct gttttatcaa cttttaggtt ttatatctag
    53341 tttaatacca ggattatcaa taccaattgg agaaatatta ataccagtcc cattacactt
    53401 gtactttgac ttatttgcag gattgttaca agcatatata tttataatgt taacaatggt
    53461 atttatatca agtgcaggag agttagatta agaaatcaac ttatattaag ataaaaataa
    53521 aataatttaa aaaattaaag ttttaaggag gaaataatta tggaaacagc aatagtagcg
    53581 gcagcatcag caataggagc agggatagca gttgcaacag gtataggtgc aggtataggt
    53641 caaggtatag cagcagctaa agctgcagaa gcagtaggaa accagccaga agctaaaggt
    53701 gatataacat caactttatt actaggagtt gctatagcag agtcttcagc aatatatggt
    53761 ttggttatat caataatact tctattcgta aatccattct ttaaatactt aggaatgtag
    53821 atttagtcct taaatatttt gagataggtt tataggtaaa tcatctcaaa cttataatca
    53881 tgagatgaac tttatcatct cgtgattata agtagttatg atttatggaa aggaggataa
    53941 ttatggaaaa agcactagta ggtataacgt gggaatttgt gttccaaatt gttaatactt
    54001 ttataatatt tttacttctg agaaagcttt tattcaagcc agtattaaat ataattgaat
    54061 caagagaaaa tgatattaaa agtgatttgg cagaaggcga aaaagcaaaa aatgaaggtt
    54121 tagctctgaa aaaagaatat gagtcaaaaa tcaattttgc caaagatgaa ggtcaagaaa
    54181 tcataaaaca agcaactata agagcagagc agaaatcaga tgatatagta aatactgcaa
    54241 agaaagatgc tcttgatata aaagaaaaag caaacaaaga tatagaacaa gaaagacaaa
    54301 aggttataaa tgaaatcaaa aatgatatat ctaacatagc actacttgca gcatctaaag
    54361 ttattgaaaa agatttagat aaatctaaac atgaagaatt gatagaaaac tttataaaag
    54421 aggtagggga agctaaatga taaatgtaat agcaaataga tatgccgaag ccctatttca
    54481 attaggagaa gaagaaaatt caactgatgt cttattcaaa gaactagaaa aagtagtaga
    54541 tatgatgact aaagttagta aagatttcta caaagtttta aaatcaccat tagtttcaaa
    54601 atcagaaaag aaaaacttgg tagaaattat ttttagtaaa gaagtaagtt ctaacataaa
    54661 aaacttttta aaagttttag tagataaaga tagaatatca tatttagaag atatcgaatt
    54721 agcttataaa gaattattaa ataagaaaaa caatgtaatt gatggagtag caataagtgc
    54781 tattccaatg agtgaaacag atattaaaga acttgaagtc aaactttcaa ataaatacaa
    54841 caaaaatgtt actatagaaa atgttgttga caagactata ctagggggag ttctagttag
    54901 aattggaaat gaacaaatag atggcactgt gaaaactcgt cttgataaga tgaaagaaaa
    54961 gctatctgaa gtaatatctt aagaatggcg gtgaacccat gaacttaaaa cctgaagaaa
    55021 taagttctat aattaaacag caaataaaaa attatgagaa taaagttgag ttgacagata
    55081 caggtagtgt tttaacagtt ggggatggta tagcgagtgt atatggatta gaaaaagcta
    55141 tgtctggtga gttgctagag ttcccaggtg aaatatatgg tatggcactt aacttggaag
    55201 aagaagtagt tggagctgtt atccttggag atgacagtga aataaaagaa ggcgatatag
    55261 ttaagagaac tggaagaata gttgaagttc cagttggaga agctttaata ggtagagttg
    55321 taaactcact aggtcagcca atagatggaa aaggacctat agcgtacaca aaaactagac
    55381 cagttgaatc tgaggcacct ggtataatag atagaaggtc tgtttatgaa ccattacaaa
    55441 caggaatcaa atcaatagat tcaatgatac caattggtag aggtcaaaga gagttaataa
    55501 taggtgacag acaaactggt aaaacatcta tagttattga cactatacta aatcaaaaag
    55561 gaaaagatgt tatctgtata tatgtagcaa ttggacaaaa acgttctact atagctcaat
    55621 tagttagctc tttagaaaaa ggtggagctt tggattatac aatagtagtt tcagcaacag
    55681 catctgaatc agcaccactt caatatatag caccatatgc tggagcagct atgggtgaag
    55741 aatttatgta caatgggaaa catgtactta tagtgtatga tgatttaagt aaacaagctg
    55801 ttgcatatag agaaatgtca ttgttactta gaagaccacc aggacgtgag gcatatcctg
    55861 gagatgtatt ctatttacat tcaagattac ttgaaagagc agctaagtta tctgatgaat
    55921 tgggtggagg ttcaatgact gccttgccta taatagaaac tcaagctggt gacgtttctg
    55981 catatatacc aacaaatgtt atatctataa cagatggtca aatatactta caaccagagt
    56041 tattctattc aggtgtaaga ccagcagttg accctggtat atcagtatca agggttggtg
    56101 gttctgcgca aattaaagca atgaaaaaag ttgcaggaac attaaaactt gcatattcac
    56161 aatatagaga acttgcagca ttctcacagt ttggttctga cttagatgaa gatactaaaa
    56221 agagacttgc tcaaggtgaa agaatcgttg agatattaaa acaaggtgag catcaaccaa
    56281 taaaagttga aaatcaagtt atgataatat atgctgttat aaataatcat ttagaggata
    56341 ttccgataga taatatagct agatttgaat cagaattgta tgcatttgta gataataatt
    56401 atccggaaat atcaagaaaa atattaggtg gagaagactt cactcatgat ttaacagatg
    56461 caataaatga atttaaagaa aagtttgttg ttgaagtata atccttttta aaaaaggagg
    56521 taaattaatt ggcaggagct ggaatcaaag caatcaaaac acgtatggga actgttgaaa
    56581 gtacaaagca aataactaaa gcaatggaat tagttgcatc ttctaagctt agaaaagcaa
    56641 aagaaaaggc tgaagattca agagaatatt ttaatacttt atacaataca gtaaaagata
    56701 ttgcccaaac aacacgtgga attagaaatg aatttttaaa agaaagagaa gtaaaaaata
    56761 aatgctatgt agtagtagct ggagacagag gacttgcagg tggatacaat tctaatgtat
    56821 taaaggaatc tgtctctcat atgaaaggta aaaaggaaac agtgattact gttggaaaga
    56881 aagcacatga atttttttct aaaagaaact acaatatagc aaaagatata aatagtgttg
    56941 aagcttgtgg atatgaagat gcgacagaaa tttcacaaac tattattgac ctgtataaaa
    57001 aaggtgaagt agatgaagtt tatattgctt atacaaaatt taaatctgct ttatcacaag
    57061 aagttgaaat tttgaaattg cttccattag tctttgaaaa agatacagac gaacaaggaa
    57121 tggcagtaaa agaagaaaaa caaaatagat caaaagtaca atatatacca tcagcagaag
    57181 cagttttaag ttatattgta cctcagttta tatcaggtac agtatatggt ggaattttgg
    57241 aatcttttgc atcagagcaa ggtgctagaa gaactgcaat ggaatcagcc acagacaatg
    57301 cgaatgaaat gctatctaat ttagagttaa gttataacag agcaagacag tcagctgtaa
    57361 ctcaagaaat aacagagata gttggtggag ttgaagctct aaaataggga ggttaggaaa
    57421 tggcaaatgt aggtaaagta gtacagattg taggagctgt actagatgtt aagtttgata
    57481 gtgaacaaag cctacctaac ttattaaatg cgttagtaat aaagttagga gataaagaaa
    57541 tagttgcaga agttgctcaa catataggtg atgatactgt aagatgtata gctatgagtg
    57601 caacagacgg acttgtaaga ggtatggaag ttgtagatac aggagggcca ataagtgttc
    57661 ctgttggaga tgaaacttta ggtagaatat tcaatgttct tggaaaacca gttgatggga
    57721 aaccagctcc aaaatctgca cctaaattac ctatacatag accagcaccg gcgtatgatg
    57781 aactagaaac tacagcagag atactagaaa ctggtattaa ggtagttgac ttactagctc
    57841 catatctaaa aggtggaaaa ataggtctat ttggaggagc aggagtagga aagacagttc
    57901 taatacaaga gcttataaac aatattgcta agcaacatgg tggtatttct gtattttcag
    57961 gagtaggaga aagaacaaga gaaggtaacg acctttatgg cgaaatgagt gagtctggag
    58021 ttataaataa aacagctcta gtatttggtc aaatgaatga accacctgga gcgagaatga
    58081 gagttgcttt aactggactt acaatggcag aacattttag agatgagcaa ggacaagacg
    58141 ttttactttt cgttgataat atattccgtt tcacacaagc tggttcagaa gtttcagcac
    58201 ttctaggacg tatgccatca gctgttggtt atcagccaac attagctact gaaatgggtg
    58261 cacttcaaga gagaataaca tcaactaaga aaggttcaat aacatctgtt caagcagtat
    58321 atgtaccagc agatgactta actgacccag caccagctac aacattctct cacttagatg
    58381 caaaaacagt tttatcaaga caaatatcat cactgggtat atatccagca gttgaccctc
    58441 ttgaatctac atcaaggatt cttgacccta gtatagtagg aaaagaacat tatgaagtag
    58501 ctagaggtgt acaatcaata cttcaaagat ataaagaact tcaagatata attgctatac
    58561 ttggtatgga tgaattatct gatgaagata agttaatagt tgcacgtgct agaaagatac
    58621 aaagattctt atctcaatca ttcacagttg ctgagcaatt tacaggaaat ccaggtcaat
    58681 atgttcctgt taaagagact gtaagaggat ttaaagaaat tcttgaaggg aaacatgatg
    58741 acttaccaga gtcagcattc ttatttgtag gaacaataga agacgctgtt agaaaagcga
    58801 agggaagtat gtagtcatgg ccagtgaatt ttcattgaaa gttgtaactc caagtaatac
    58861 tttttatgat ggagatgttg aaatgatagt agttagaact acaaaaggag acaaaggggt
    58921 gttgaaaggt catataccat ttgtttcagg tatacctgta ggaactttaa agataaaaaa
    58981 agagggaagt tttaaagagg cgaaaatagc agaaggattc attaatgtaa ctcaagataa
    59041 aactgtcata ttgacagaat ctgctgagtg gatttaataa attaatttag agtataaaaa
    59101 gtcattttga ccaaaaaaac ttttgggtaa aatggctttt ttgtgttttg gtgttaataa
    59161 aataacgata aaattgtaag tttttagtga taataaattc acaaaatgtt taaatttact
    59221 gccaaattat gttgtaatta ataagataaa gaagatttag atagctttta tgtaagtgaa
    59281 aaagtcttca tataagaaat acatataaaa tttttataaa atttaaaaaa tttgcttagt
    59341 tgtgtagtat aataaataat ataatagatt tgtatataat attcattaca aataatttta
    59401 aaagttacag ttttattata atgattatta aattaagata agtaacataa actaaataat
    59461 aatgtgtatt atcgatagta aatttataaa ttcattatta attattgaaa gaagtattat
    59521 aaattttctg gaggaacaat gaatatattt gatattggcg tagatataat tgaaattgat
    59581 agaataagaa aggctgtaga caaaaataat aggtttttgg agaagatatt tacagataga
    59641 gaaatagagt attttaattc taagaatttt aaagcagaaa gtatagcagg taatttcgca
    59701 gccaaggaag ctataagtaa atctataggt acaggaatta gagtgtttaa ttttaaagat
    59761 atagaagttc tcagagatga aatgggaaaa ccaatagtaa aaacttataa taatctagca
    59821 aaaatgtgca tagattataa tgttttagaa ataaaagttt caatatcaca ttcaaaagat
    59881 tatgctatag caaatgcgat aaccataatt aaggactaag gagtgattac attatgatgg
    59941 ataaaacagc aaaagaaata atgacaacag atgtaatagt agcaaaacaa gatgatagta
    60001 tagcagatgt agctaatatg ctaattgcag aaaaaatagg aggtctgcca gttgtagatt
    60061 cagagaatag agttgttgga ataatttctg aaacagatat tcttaaaaaa gaaaaatata
    60121 tagaagcacc tctctatata aatctattac aaggattgat tttcttagat gacttaaaaa
    60181 aagttgaaaa agatataaaa caagtagctg cttataaggt tggagaactt atgtctaaag
    60241 atataataaa ggttcatgaa gatgataagt ttgatgatgt agctaatgta atgattaaaa
    60301 aatcaataaa cagagttcct gtagtagatg atgataacaa acttaaaggt ataatttgta
    60361 gatatgatat aataaaagct ttatacaatg aataaactga agtaggaggt gtgatgtgag
    60421 aaaaaagtgg accatagtat gtattatgtt cttggcactg gttataattg taataggatg
    60481 ccaaaaacga cagtccacaa aagaagaagt atacaaagat tttcaaaagc agatttctga
    60541 tatgaattat tacagttgta aagctgaagt agaagtagtt ggaaataaaa gtccacacaa
    60601 ttatgtttta attcatactt ataaaaaaac cgataactat aaattagaag taatttcccc
    60661 aaaacattta aaagggaaaa gtatagaata tcaaggtgat aaaatattag ttaaaaatcc
    60721 aaagattagt gatgtagtgg agttacctaa tacaggaaaa aataatcaat atctttttgt
    60781 aggagacttt ataaaaaatt atcttcaaaa tgaggagatg aaagtaaagt tatcgaaagg
    60841 acatttggtt ttagagactt ttattcctgg ggataataaa tattttaaca agcaagtatt
    60901 atatgtaaat gctgacacaa aaaatcctga aaaaatggaa gtgttagata aagagggagt
    60961 gccaagattt acagtaaaat acaaagattt tgaatacaga aactaagggg gactaaagac
    61021 atgcaaaaaa taacagtgcc tacatgggca gagataaatc tagataactt aagatttaac
    61081 ttaaataata ttaaaaattt attagaagaa gatattaaga tttgtggagt aataaaagct
    61141 gatgcatatg gacatggtgc agtagaagtt gcaaaattgc tagaaaaaga aaaagtagat
    61201 tacttagcag tagcaagaac tgctgaagga attgaactta gacaaaatgg cataacactt
    61261 cctattttga acttgggata tactccagac gaagcctttg aagattctat aaaaaataaa
    61321 ataactatga cagtttattc tttagaaaca gcacaaaaga taaatgaaat tgcaaaatct
    61381 ttaggagaaa aagcctgtgt tcatgttaaa atagactcag ggatgactag aataggtttc
    61441 caacctaatg aggagtcagt acaggaaata atagaattaa ataaattaga atatatagat
    61501 ttagaaggta tgtttactca ttttgctaca gctgatgaag taagtaaaga gtacacttat
    61561 aaacaagcta ataattataa atttatgtct gataaattag atgaggctgg tgtaaaaata
    61621 gctataaaac atgtatcaaa cagtgcagct attatggatt gccctgattt aagattaaat
    61681 atggtaagag caggaataat attatatggt cattatccat ctgatgatgt atttaaagat
    61741 agattagaat taagaccagc catgaaatta aaatcaaaaa tcggacatat aaaacaagtt
    61801 gaaccaggtg taggaataag ttatggacta aaatacacaa ctacaggtaa agaaacaata
    61861 gctacagttc caataggata cgcagatgga tttactagaa tccaaaaaaa tccaaaggtt
    61921 cttattaagg gagaagtgtt tgatgtagtt ggtagaatat gtatggatca aataatggtt
    61981 agaattgaca aagatataga cataaaagtt ggagatgagg ttatactatt tggagaaggc
    62041 gaagttacag ctgagcgtat agctaaagac ttaggaacta taaactatga agtgttatgt
    62101 atgatatcaa gaagagttga ccgtgtttat atggaaaata atgagcttgt acaaataaac
    62161 agttatttgc taaaataaaa ccatgatatt ataatctggg aggcgatttt gtgtacgata
    62221 agagtaaaga aaaaatagaa gttactttac ctgactctct gatttctgaa gttgatagta
    62281 tagttcagat ggagaacagt aacagagaag attttgcaaa agctgctttt cagttctata
    62341 taactcagaa aaagaaaatt catattaaag aatctatgaa aacgggttat agagaaatgg
    62401 gtcaaattaa tctgtcacta gctgaattag gtatgacagt tgaagaagta tcttctgatg
    62461 ataaaaatga agggaagatt gcccaaggtg agtactaatt gtgaaataaa gcgtggtgat
    62521 ttatattacg ctgatttaag tccagttgtt ggttcagagc agggaggcgt tagacctgtt
    62581 ctgataatac aaaatgatgt aggtaataaa tatagtccta cagttatagt atcagctata
    62641 acatctcaga ttaataaagc caaattacct actcatgtag agataagttc caatgaatat
    62701 gggcttaata aagactcagt aattctttta gagcaaatta gaactatcga taaaaagaga
    62761 ctgagggaaa aaattggttg tctagatgaa aatatgatga taaaagtaga tgatggactt
    62821 caaataagtt taggattgtt tactttttaa agagggattt gtcttttatt agacaatccc
    62881 ttttttcttt taaatatctc ttaaggttta attttaatgt actatgttaa taaaattaaa
    62941 aataacgcaa aaaaatagca taaaagtgat ataataatat ggaattgata taaaattacg
    63001 aactcaaggg aggtaattgc atgagagacc ataaaggatt aaatgagatt gcgcgtatca
    63061 taagaagaga tatagtttca atgatacata gagccaaatc tggacatcca ggagggtcat
    63121 tatcagtagt tgaaatactt actgcgttat actttgatga aatgaatgtg gattcttcaa
    63181 atcctaaaat ggaggataga gatagatttg tattatcaaa aggacatgct gcaccagcat
    63241 tatatgctac attggctgaa aaaggctatt ttgataagga agaactgaat ggattaagga
    63301 agataggaag gatgttacaa ggtcatccag acatgaaagg cacgccaggt gtggaaatat
    63361 ctactggttc tttaggtcaa ggtttttcag ttgcatgtgg tatggctatg gcatcaaagt
    63421 tggataatgc tccgtggaat gtgtatactt tgcttggtga tggtgaggtt caagaaggaa
    63481 ttgtttggga agctgctatg agtgctgcac attataaact tgataattta attgcttttt
    63541 tagataataa tggacttcaa atagatggag atatagaaag cgtaatgagt ttaggttcaa
    63601 tagttgataa atttaaagct tttggttgga atgtaattga gatagatgga catgattttg
    63661 accaaatatt tgcggctctt gatatagcta aatcaacagt taaaaaacct acaatgatag
    63721 ttgcaaaaac tataaaaggc aaaggaatat cttttatgga aaatcaagca ggatggcatg
    63781 ggacagctcc aagtgatgag gagctagaaa aagccttgct tgaattagga ggtgctgaca
    63841 atgagtaaaa tggcgacgag agaagcatat ggtaaagcat tagtaaaatt aggtcaaata
    63901 aatgacaatg ttgtagtatt agatgcagat ttatcaaagt ctacaaaaac acatgatttt
    63961 tacaagtcat ttccagatag attttttaat atgggtatag ctgaacaaaa tttaataggc
    64021 gctgcttgtg gattatcaac tgctggtaaa ataccttttg caagtacttt tgctatgttt
    64081 gctacgggaa gggcttttga gattataaga aattcagttt gttatccaaa gctaaatgta
    64141 aaaatatgtg ctactcatgc aggtcttact gttggagagg atggagcatc tcatgaaagt
    64201 gtggaagata ttgctataat gagagctata ccaaatatga cagttcttgt tccagctgat
    64261 ggagttgaaa cagaaaaaat tatttttgaa atagctaagt ataatggacc tgtttatgtt
    64321 agattaggga gaagttcagt atcagtttta tttgatgaag attataaatt tgaaatagga
    64381 aaaggtacag tcttaagaga aggaaaggat gtatcaatta tagcttgtgg aattatggta
    64441 aatgaagctc tattagcaca agaaaagttg caagaagaag gtataagtgc tagagttata
    64501 aacatgtcct cgataaaacc tatagacaaa gatttaatat tagaatcagc aaaagaaacg
    64561 aatgctattg taactgtaga agaacatagc ataattgggg gattaggttc tgctgtaagt
    64621 gaggtagtag gagagtcttg tccaaccatt gtaaagaaag ttggaattaa agatacattt
    64681 ggagaatctg gtactccaaa tgaattgtta aaaaaatatg aattaacttg tgatgacata
    64741 ataaagactg ttaaagaagc tattattgca aaaagaatgt aagagatata aattattcat
    64801 gtttgttaat aatataatat atttaaaaga gaggtataaa gtgttatatt aatttatatc
    64861 tctctttttt ttatatgata tcaatatatc aaaaatgtaa taaaatattc aaatttttac
    64921 aaaaatagag aaaatattca aatatatatt gactattcag aaaaatatga ctaatatata
    64981 atttatagag aaactaattt tatatataat gactacttag ataaaagaat ctaaaaaaat
    65041 tatgagagga ggagtagggt ataaaatcag attataagtt ttaagttatt atactaaaaa
    65101 gctataaaac agttatcatg tattttatgt taaaggaaat tgtaggtagt ttatcgaatt
    65161 gtttaatcag aagaaaaaat ttcacatggg gaggtaactg agatatgtca gaaaaagtaa
    65221 atgttaaaac agtcatcagt ttcgcaggtg cgtatgtagc aacagtaatc ggttctggat
    65281 ttgcaacagg acaggaaata atgcaattct tctcttttta tggttttgca ggtattattg
    65341 gtgggataat ttcaatggta ttattctcat ggatgggtgc ttcagttatg tcaaaaggta
    65401 aagagcttca acttaaagaa cctatcaaaa tttatcgtgt ttattgtggt aagtatttag
    65461 gaatattctt tgaatggttt ggacctttat tcttatttgg tgttttcgta gtaatgattt
    65521 caggagcagg agcaacttta actgaatact atggattaaa tccatttgta ggtagagtag
    65581 gtatggcagt agtagcatta ttaactgttt cactaggtct tgataaatta tcaaagatac
    65641 taggtggaat agggcctata ataataatct ttacactttt agttggtggt ataagtttag
    65701 ctaaaaacat aggtaatata ggagaagctg cacaagttct tagcactgta aagatagcta
    65761 aaccagttcc aaatgcctat ctatctggtg taatatatac tacttataac acaattgttg
    65821 ttatggcatt cttaactgga ttaggagcaa gtgctgctaa caaaaaagaa gctatttgtg
    65881 gtggtatatt aggtggagta gcacttatgg ctgcagctat aatgatgcac ttagctattc
    65941 tttctgatat aggaaactta tattcaaaag caataccatc attattctta gcagataaga
    66001 tttcaccagt aattggagtt ttattctcaa taattcttat attaggtata tatacaacag
    66061 ctgtaccttt attatggtca gtaactaata gatttgtaga tgataaacat cctaagttta
    66121 aattaataac tttaatagca gctatattag gtcttatagg tggcttccta ccatttgata
    66181 agctggttgg tattttatat ccatatactg gatatatggg cgtcataata ctggtttgtg
    66241 ttctttatag acagattaca aaaacatctg gatatcaaga aggaatcagt gacaaataag
    66301 tattttttaa tattgtaaac tcaagagcta tatgaaaaca atgaaaatgt tttcatatag
    66361 ctctttttat tttttagctc gtttattatg aaatagaaaa aacatgtttt ttagttacat
    66421 tacatatatt tataattatg tataaatata tactaatcaa taatttagag tctaagataa
    66481 gtttataaat catatattta gaatatatgg gaggagtgat aagattgaat gtaaagttta
    66541 atattaaagg tataatttat ggagttatag ctcttgtatt cgttataggg ggatttatat
    66601 tcataccaag tatgtttgta gagaaatcta aacccataga ttatacagta ttacaaagaa
    66661 attcaatacc agaaaagata ttagatgtga tggataagta tacaaatgaa gaaagagcat
    66721 tagcggctaa aatcgataac aaaatataca ttatagtgac tagaggaaat aataaatatg
    66781 gtatagaaat ggacaaaata gaaagtgtgg ttgaggaagg aaagtatgtt ttgagagtca
    66841 agataaagta taaagataag gaagattctt ttccatacat agttgttgaa acaaatatga
    66901 gtgaacttcc agatagaata gaattaaatg cgacgaaata agaaggtatt ttataattaa
    66961 ataactgcat attgtacaat aaagtcatgg tttttattaa tgtaagtaaa ttgtgtatgg
    67021 ttcttattgt tgtaaaagcc atgacttaaa atgcttataa agtaagatat taacagtagt
    67081 atttattact acattaaatg gggtctggaa atacttaata ttctaactat ttggagtgat
    67141 aattctagtt tcagtaacta tgtagtctaa ttgtgcatca tgagtttctt ttggaataga
    67201 atcgaatatc tggaagtcaa atgctatgcc gatagttata gcatcttttc ttaagttttc
    67261 taaaaatcta tcataaaatc ctccaccata tcctaatcta tagcaatgta tatcatatgc
    67321 tacagctggt acaattacaa catctaaagc cttaatatca attgtaggtg atttttcgtt
    67381 aggttctctt attccatatg ctccaattct caatccctct tttaaatctg ttatttgagt
    67441 agggattaat gtatgatttt cttttattgt gatgggactt gatactattt tctttagaga
    67501 caaaagtttt ttgattaaat tatctgtttg aacttcattg ttaaaattta gataaagcat
    67561 tatattagtt gcatttctta tatcttccat ttgaagtaat ttttcagtga ttaaatttga
    67621 attactaagt acgaagtttg cactcttatt ttttcttgat tcaataactt tttttctaaa
    67681 ttcttttttc ataaaataat tcctccctta atatgttata atgtgtacag caattgtatt
    67741 taatataaat tttagtataa tttattgtaa taaagcaata tatttgggta aatgtaataa
    67801 aaataacagc tagtcatata ataataatag tttatgtaaa aggagatgta tcttgtgatt
    67861 tcaaagaaga aagctatttt tttaggggtg attttagtaa ttataacagc tatggttaca
    67921 tcagcatttc agttgacatt ggggaataaa gttgtaatat cgaaagaact ctatgaagac
    67981 tataaaaaat atgataagtt gttaggacta gaatctatta taaaacaaga tttttataaa
    68041 aaagtatcag atactgattt ggtaaatgga gcagcaaaag gtctatttct aggaacaaat
    68101 gataagtatt ctggttatta tactaaagat gaaatggaga atctaattaa tgatagtgaa
    68161 ggttcttatg ttggtgtagg tatgtatata ggggcatcaa aagatggtgg cttagtagta
    68221 gttcccatga aagattctcc agcagagaaa gccggtgtaa aatcagggga taaattagta
    68281 aaagtcaatg gaaaatctgt ctcatataaa aattcagatg aagctgttcg tatgatgaag
    68341 ggtaaaaaag gtaaaacagt tgaactgact atattaagag aagataaaca attgaacttt
    68401 aaagtaaaaa cagaccagat aattgagaag agtatagaaa gtaaagtaat tgataatgat
    68461 ttaggatata tagaaattac ccaatttata tcaagtacat atactgactt tgataaagct
    68521 ttaaaagaat taaaagcaaa aaatatcaag ggattagtaa tagaccttag aaataatcct
    68581 ggtggaatgc tagatatatg taaagaagtt gctgatgagt taattggtga aggaactata
    68641 gtatatacaa aagataataa gggaaatact gagtacttga aatctgataa agaaaaattg
    68701 ggacttccaa tagtagtgtt aactaatgga gaaagtgctt ctgctgctga aatattaaca
    68761 gctgcaatcg ttgataataa agaaggtatt tctgtaggga ctacaacttt tggtaaaggg
    68821 ttggtacaat cagttgtaag attgaaggat ggaacaggat acaagctaac tactgctcaa
    68881 tattttacac ctaatggaga ttatatcaat gaaaaaggta taaagcctac tattgaagaa
    68941 aaagatgaaa ataaacagtt agatgtagca actaagtggc ttagagaaca gattgataaa
    69001 taggatttaa tttttataaa cttatactat aaaataaaga acattataaa agagatgtct
    69061 caaaatgaac tttttagttc atgagggagt ctggaaatat ttatgtgtat tctttaaata
    69121 aaaatttatt ttttaagtga taattaaatt tttacagaca gggctatggt tttaaaaatc
    69181 atagccttat tttgatattt tttaaaaaca cattgcaacc cagttgttcc aaatattata
    69241 tcatttactt ttaaaatatc gcaaactgca tattatatat tcattataat ataatttatc
    69301 taactagaac ctcagtttac taattaaatt agatgcatag aataactttt ttaaacattg
    69361 aaaataaatt aaactctaaa cacatttaaa tataaattta tatatcattt tgacttggtt
    69421 aaacaatttc atacttatcg atataaaaat aggttataat ataaatgttc attatcttat
    69481 aacctatttt atataattta ttcctaaaac atgtgaatgt tttttatgat agtttgaaga
    69541 aattataaaa tcactttata attgaatatt atatataaat taatttaaat atagaaagga
    69601 aaatatatgt acaacaatat caaaaatatt ttaaaagaaa atcatataac gtttgaagaa
    69661 tatgaccatg aacctatttt atcatttgaa aaagctaaag aaataagaga aaaattacaa
    69721 tatactggag tagaaagtaa aagtttattt ataaaagata ggtctggaaa ttactatata
    69781 tttgtaacca cagaaggaaa aaaattagat ccaaaaacta taaaaaatgt tttaggtgga
    69841 aaagtatcta tatgttcaaa agaagaatta acacaaaaaa cacaatgttt gcctggatgt
    69901 gtatctcctt ttggatatga gaaaaatatc tctcttgtaa tagatcaaga tatatttaac
    69961 catgataaaa taatcttttc accagggata ccagaaaaga catttattat tacagctagt
    70021 ggatttaaaa aagtaataaa caatataaac aatacaactt ataaatatat atatattaat
    70081 gaattttaat cataattgta aattagagaa aataacatta gaaatcatgc ttaactatag
    70141 tgtaaataaa ttatatttaa cataaaatat ataaaatcaa caaaatgatt ttagtctatc
    70201 tattagatat tcttcgctct caatgcttaa aacttttaga tatatacaat aagtgctttc
    70261 atttgtaaaa atttctatag tattatcttg tttatttaca cctacaatat ctttaaaatt
    70321 gatatgattt ttagtatttt tacatttgaa aatatatctg ttatcaatca aaatctcatc
    70381 attagtaatt gaaatatagg gtttatctca tgctttatta aaaatttata tgtttgttca
    70441 agataaaaac ttacaaataa taatagaaaa gttactttaa atgtacatat tatcgaaaat
    70501 attatcacaa aaatacttat aatatatatt tgtttaaaat aacctctatc gcaatagttt
    70561 attaacgata tggaaataaa agtgttaaat cagattttgg agaaataact ttaaatattt
    70621 ccagactctt tttagacagc ctccataacc ttatattgaa cctatttatt aactttgtac
    70681 ttacagatac catttatata agtttcgtgt atattaaagt cattatctgt tactataaag
    70741 tctgcatcca taccttgata tatagagcca cagacattat caatattaca acttaaagca
    70801 gggacatatg tagccatttt tattgcatct tctaaagttg atatgttcca atcaactata
    70861 tttctcacag ccttgtccat agttaataca cttccagcta aactcccact atttaatctt
    70921 gcaacactat tttttacatt tacattaaac ttaccaagag tatattttcc atcctccata
    70981 gcaccagctc tcatacaatc tgtaattaaa gctatgttat tactagactt agcatccatc
    71041 attattttaa cagctattgg gcttacatga tgaccatcac aaattaattc agcataagta
    71101 tcttttagta ccatagcagc cccaaccatt ccaggttctc tatgatttaa aggactcatc
    71161 ccattatatg tatgtacaaa cactttagca cctgaattaa cgacttgttt aacttgctca
    71221 aatgtagctg aactatgacc aagagaaact gatatattat ttttagttgc atatcttgtt
    71281 aattctattg aacctttacg ttctggagca attgctattt ttcttattaa atttttcgat
    71341 tttttttgcc ataattttaa tatattgatg tcagggtctt taaaatattt ttcattttga
    71401 gcgcccttat atttttctgt aaaaaatgga ccttctaaat aaatcccttg tatttttgca
    71461 ccctcaactc gattgaagct attgcttata ttttctacag aatcacttag tgtatctaca
    71521 gaatcagtta aagttgtagg taggaaagat gttactccat attttaataa gccttttgaa
    71581 attgtgttta ttgcttcaaa tgtattgtcc atgacatctg cacctaaaag accgtgaatg
    71641 tgagtatcaa ctaagccagg agcaatatat ttacctgaaa aatctataac attatcagta
    71701 acattaggtc tttcttgttg aaattcaccg aatttgccat taattatact aaggtaacct
    71761 ttttctttga ttccatgttt cataaaaaat ttatctgcat aaataaaact tttcaaaata
    71821 acctccttat aattatacta tcattgtggc attgacgctt ataatatcat tctgttttct
    71881 tgaaagctat ttaacttact atcttacatg tcttactcta tatacaaatt tatcgcttct
    71941 agcgacactc aaagtaaatt caataactat attgtcatca ttatatgtgg tacgaagtaa
    72001 tttcagacaa ggtgaatctc ctggtacttc caataactta gcttccttat cagagattat
    72061 tccagctgaa aattcttcat cagcaacttt aataatctcg ccataatctt ctctaaatat
    72121 ttcatataaa ggtttttgtt cgattttttc ttttgtcaat cctataaatt ctttcatagg
    72181 aagatatgtt ctttcaagca tcataggaag gtcatcagca agtcttaaac gcattatttt
    72241 tatcattttt tcaccagtag ttatacctaa tttttcagag aaatactttg tactttctac
    72301 tacctcaaat gataatacct ttgtacctgg cttttttcct tgtgttctca tataatctgt
    72361 aaaactataa ctttccatta agttttgaga attttgactt agtgcagcaa caaaagttcc
    72421 ttttccatgt cttttgtata tatatcccat atgttccaac tcagccatag ctagtctaac
    72481 tgtggttcta cttactccat attcatcaca aatttttctt tcggaaagca ttctatcgtt
    72541 tggttccatc tcattttcaa tcttagttct taatatctca acaagctggt catatattgg
    72601 tcttttatca tttcttttta tcataaaaat atagtccttt ctaagtggtt attaccacaa
    72661 tttgattata gaatatagaa ttatttatgt caatgaataa agtttaatca aaattcaata
    72721 agtaaggcta ttaatttatt ataaaattat ggtacattga caaaacaagt aaaataattt
    72781 atattcaaat tggtaataac cactttggat atattatatg aggtattttt tattttacag
    72841 attaatttat tgtttagaaa agtaaaaatt aataatgagg agaatctagt atgattacag
    72901 taataacatt caacccatct atagatagaa tgtatagagt gaataatata aacataggtg
    72961 aggtgcaaag ggtagtaagt aagaatgcaa ctgctggagg taaaggatta aacgtagcta
    73021 aggtatgtaa aattttaaaa gaaaatcctt tagctatggg atttctaggc ggatttaatg
    73081 gagaatttat aaaaaatgaa cttagaaaac tagatataca aaataaattt acaaaaatag
    73141 agcaggaaac tagaaattgc ttaaacataa ttgaggacaa taaagttagt acagaatttt
    73201 tagaaaaagg accaatagta gaaaaaagcg atttagagag atttgaaaat gatatagagg
    73261 aagtactaaa aaatactaaa atactggtag cttctggtag ttattgtgag aatatgccga
    73321 tagattatta tgaaaagata ggaaatatat gtagagcaaa taatataaaa tttatattag
    73381 atacatcagg agaagcatta aaaatagctt taaaatcaaa accatattta ataaagccaa
    73441 atatagatga aataagacat ttattaggaa tgaatataga atcaagagag gaaattatct
    73501 tgtcaggaaa aaaacttatt gaaatgggtg cagagaatgt atgtatatct ttaggaaaag
    73561 atggtatggt gtatttaaac gaagataatg tatatgatgt aaaagtacca gttgtaaagt
    73621 gtataaatac tgtaggtagt ggagatagca cagtggctgg atttagtgta ggtattttaa
    73681 ggggttataa aatagaaaat ttacttaaat ttgcaaatgc ttgtggtata agtaatgctt
    73741 taaatatgga aactggattt gtagatttgg gagaaattga taaatatcaa gatttagttg
    73801 aagtaaaaaa gttaagttaa atacatttaa tgggaatata ataaatttaa tgttgttgta
    73861 atagatttta atataaaaga tatagtctta tataaaaata ggttagaaaa attcattttt
    73921 aacctatttt tataataaat atctatttta ctgaatttat aattttctct agtaatcttt
    73981 gagctttgat acactcttct ccattaatag ctggttttat attattttct atacaatcaa
    74041 taaaatgatt tgatatatcc tcaaaaccct tttgttttaa tatatttacc catgcaccac
    74101 tttgctttaa agttaggttt ccaccttctt ctatttccag tacattaaga ttcttaactc
    74161 tttgaatctt accctttgaa agaatttcaa cttgttctaa ctttgttcca gaatctctat
    74221 gcatagaggt gtttatagag aaatttttac ctttaagttt atgacttaca aatataagat
    74281 tcttattgtc tgttaaaaat aaatcctctc cactaatttc aacatcttca tttgctaacc
    74341 ataaagcagt gtcaataaca tgtatatagt catctataag agtactgtcg aatctaacat
    74401 ttcttaagga atttaatcca tgtttacata tattgataga tacaatttct gtagcattat
    74461 ttttaatttc tttgtacata ggacagaatc tacggttgaa tccaaccatt aaatttaagt
    74521 tttttttcgt acttaactcg ataagttctt ctccttgact tactgttgaa gcaagaggtt
    74581 tgtctacata tacatgaaca cctaaattta ataatatttt tataatttca tagtgtgttt
    74641 ctgtagagct atgtagaaaa atacaatcac attttttagc tagggactca atagaatcga
    74701 atggcatgat tctataatca ctacaaattt tttccctttt aactttattt ggagtaaaag
    74761 ctcctacaaa ctcaaatctc tcagacttag ttagtatagg taaatacgcc ttttgagcta
    74821 tggagccaag acctatcatt cccattttta tatttttcat aatactttct cctaaggttt
    74881 ttatatttac agaattgatt ataattcaga cacataaatt tgtaaacttt gtatcaaaaa
    74941 ataaatttaa agcttatata agtaaattag cgaaataaga aatattgata aagtaatttt
    75001 gtaggatatc tataaaattg attgatataa atattttatg tattgacaaa aaattcaaat
    75061 taatttatat ttggattagt ggtaattacc actttggtct gaacaagttt ttatcgtaaa
    75121 ataaaaatac taaagtatat agagtatgat tttattaaat ttttaaagat aaactataaa
    75181 attaattaaa atctatagcg tatattttat agtgagttta agtagtacta aaaaatctaa
    75241 gcaaaaaatt ataaaagagt atattttttt atagtttaaa gtggttataa cctcattacc
    75301 aaatgtaaat gttacaagta tgaaaggaga atgaaaatgt ttaaattaga agaacaaaaa
    75361 ctaaaagatt taggtgcaat aataacaact aatgaaataa aacaacagcc tgaattatgg
    75421 ttagagactt atgaaatata taaatctaac aaagaaaaat taagtagatt catagataca
    75481 ataagtaata atcatgggca gtttagagtt atatttacag gtgctggaac ttcagcttac
    75541 ataggaaatt caatacttcc ttaccttaag aataaaaatg acataagaaa atacatattt
    75601 gaagcaatac ctactacgga tatagtttca aatccatatg attacttaaa aaaagatata
    75661 ccaacattat taatttcatt tgcaagaagt ggaaatagtc ctgaaagttt ggctgcttta
    75721 aatttaggga ataagattgt agataatttt tatcatttag ctataacttg taatccgcaa
    75781 ggagaactag ctaagatgac taaaaacgac gaaaataatt acttgttatt aatgccatca
    75841 aaatcaaatg atgaaggctt tgctatgaca ggaagttttt cgtgtatgat gttatctgct
    75901 atgttaatat tcgatagttt agaagatgat gtagaaaagt catatataaa tgcaataatt
    75961 gaaatgggaa gaaatgttat agatagaaaa gatgaaatac atgagttaat aaataaagat
    76021 tttgatagag ttgtatattt aggttcagga ggattaggtg gtttgacaca agaagcacaa
    76081 ctaaaacttt tagaacttac agcaggaaaa atatctacag tgtatgattc tcctatgggg
    76141 tttagacacg gaccaaaatc atttattgat gaaaatacac ttgtatttga atttgtatct
    76201 aactgtttat atacaagaaa atatgattta gatgttttag aggaaataaa aagggataaa
    76261 attgctaaat tcacttgtgc agtgtcagta gaaaatgaaa ataacttctc aggaacaaag
    76321 tttgagttta aagaaaagta taataaatta ccagatgtgt atcttgcaat gccatacata
    76381 ttgtttgcac aaactatagc attgtttgta tcggtaaagg ttggaaataa gccagatact
    76441 ccatcagcta caggaacagt aaatcgagta gtaaaaggtg taacaatata tgaatattaa
    76501 aagataagat taaaatatta taactaaata atttgggagg gtatcaatgt ggcattagta
    76561 acaacaacat caatgcttaa aaaggcacaa gatgaagggt atgcagtagg agcatttaat
    76621 gtagaaaata tggaaatggt aattgctgtt atagaagctg ctgaggagtt aaattctcca
    76681 gtaatattac aaactactcc atctactgta aaatatgcag gtcttgatta ttatctagca
    76741 aatgcaaagg ttgctgcaga aagagtaaat atacctgtag caatgcatct ggaccatggt
    76801 tcaagttttg accttgcaat gaaagcttta agaagtggat atacatcaat aatgatagat
    76861 ggttctcatg aaagctttga aaataatata tctatatcta aatcagtagt aaaagcatgt
    76921 agtccttctc ttataccagt ggaagcagaa cttgggaaag ttggtggaaa agaagatgat
    76981 ttagatggcg ggaatagtaa tgattataca aatccaaaag aggcaaaaga gtttgtcgat
    77041 agaacaggaa tatcttcatt ggctattgct ataggtactg cacatggatt gtataagggt
    77101 gaacctaaaa tagatttaga taggttatca gaaattaaaa atgtagtttc aataccttta
    77161 gtattgcatg gaggttcagg aatacatgat gatattataa aagaagctat aaaaagaggt
    77221 attgcaaaag ttaactatgc aactgaatta agaattgcat atagtaaagg ggttaaaaaa
    77281 gttttagatg aagattctga ggttatagac cctaaaaagt atggattagc agggcttcaa
    77341 tcagtaaagg attttgtgaa agaaaagatt aaagtgtgtg ggtctgtaaa tagagtataa
    77401 aaataaaata tcctaaattt attttagata agtttaggat atttgttata tgaaaaattt
    77461 atattaatta tatgtaaatg gtgtattttt ttcatttaat tgatgaaaaa tatcagcttt
    77521 t
//
LOCUS       DAEPXW010000004        77295 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.004, whole genome shotgun sequence.
ACCESSION   DAEPXW010000004 DAEPXW010000000
VERSION     DAEPXW010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 77295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77295
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.004"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(501..2105)
                     /locus_tag="KRM55_000236"
     CDS             complement(501..2105)
                     /locus_tag="KRM55_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1592509.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENHIRPVMIHAQTVREDQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            2491..3417
                     /locus_tag="KRM55_000237"
     CDS             2491..3417
                     /locus_tag="KRM55_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH1592510.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(3537..4535)
                     /locus_tag="KRM55_000238"
     CDS             complement(3537..4535)
                     /locus_tag="KRM55_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBH1592511.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            4639..5076
                     /locus_tag="KRM55_000239"
     CDS             4639..5076
                     /locus_tag="KRM55_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1592512.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            5162..5749
                     /locus_tag="KRM55_000240"
     CDS             5162..5749
                     /locus_tag="KRM55_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH1592513.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFTGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(6049..6669)
                     /locus_tag="KRM55_000241"
     CDS             complement(6049..6669)
                     /locus_tag="KRM55_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HBH1592514.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEVDLTKEINDISIKLS"
     gene            complement(6677..7444)
                     /locus_tag="KRM55_000242"
     CDS             complement(6677..7444)
                     /locus_tag="KRM55_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HBH1592515.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGVIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(7485..8306)
                     /locus_tag="KRM55_000243"
     CDS             complement(7485..8306)
                     /locus_tag="KRM55_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592516.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            complement(8665..10575)
                     /gene="phnW"
                     /locus_tag="KRM55_000244"
     CDS             complement(8665..10575)
                     /gene="phnW"
                     /locus_tag="KRM55_000244"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBH1592517.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(10854..11639)
                     /locus_tag="KRM55_000245"
     CDS             complement(10854..11639)
                     /locus_tag="KRM55_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH1592518.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(11856..12086)
                     /gene="dltC"
                     /locus_tag="KRM55_000246"
     CDS             complement(11856..12086)
                     /gene="dltC"
                     /locus_tag="KRM55_000246"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBH1592519.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(12105..13253)
                     /gene="dltB"
                     /locus_tag="KRM55_000247"
     CDS             complement(12105..13253)
                     /gene="dltB"
                     /locus_tag="KRM55_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBH1592520.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(13253..14767)
                     /locus_tag="KRM55_000248"
     CDS             complement(13253..14767)
                     /locus_tag="KRM55_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBH1592521.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDEKDFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(14888..16078)
                     /gene="dltD"
                     /locus_tag="KRM55_000249"
     CDS             complement(14888..16078)
                     /gene="dltD"
                     /locus_tag="KRM55_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBH1592522.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(16366..17385)
                     /locus_tag="KRM55_000250"
     CDS             complement(16366..17385)
                     /locus_tag="KRM55_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH1592523.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQAITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(17561..18100)
                     /locus_tag="KRM55_000251"
     CDS             complement(17561..18100)
                     /locus_tag="KRM55_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBH1592524.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYRLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(18201..18881)
                     /locus_tag="KRM55_000252"
     CDS             complement(18201..18881)
                     /locus_tag="KRM55_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBH1592525.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(18910..20199)
                     /locus_tag="KRM55_000253"
     CDS             complement(18910..20199)
                     /locus_tag="KRM55_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH1592526.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            complement(20648..22249)
                     /locus_tag="KRM55_000254"
     CDS             complement(20648..22249)
                     /locus_tag="KRM55_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1592527.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     YDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(22360..23037)
                     /locus_tag="KRM55_000255"
     CDS             complement(22360..23037)
                     /locus_tag="KRM55_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592528.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(23050..23745)
                     /locus_tag="KRM55_000256"
     CDS             complement(23050..23745)
                     /locus_tag="KRM55_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH1592529.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(23797..24996)
                     /locus_tag="KRM55_000257"
     CDS             complement(23797..24996)
                     /locus_tag="KRM55_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBH1592530.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARNLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(25257..27302)
                     /locus_tag="KRM55_000258"
     CDS             complement(25257..27302)
                     /locus_tag="KRM55_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1592531.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(27713..28522)
                     /locus_tag="KRM55_000259"
     CDS             complement(27713..28522)
                     /locus_tag="KRM55_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1592532.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(28606..29139)
                     /locus_tag="KRM55_000260"
     CDS             complement(28606..29139)
                     /locus_tag="KRM55_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1592533.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(29289..30638)
                     /locus_tag="KRM55_000261"
     CDS             complement(29289..30638)
                     /locus_tag="KRM55_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH1592534.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGADLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(30650..32032)
                     /locus_tag="KRM55_000262"
     CDS             complement(30650..32032)
                     /locus_tag="KRM55_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH1592535.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNRDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            32276..33490
                     /locus_tag="KRM55_000263"
     CDS             32276..33490
                     /locus_tag="KRM55_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH1592536.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNNKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            33667..35580
                     /locus_tag="KRM55_000264"
     CDS             33667..35580
                     /locus_tag="KRM55_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1592537.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGIFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNALFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            35851..36825
                     /locus_tag="KRM55_000265"
     CDS             35851..36825
                     /locus_tag="KRM55_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH1592538.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            36846..37121
                     /locus_tag="KRM55_000266"
     CDS             36846..37121
                     /locus_tag="KRM55_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1592539.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            37134..38297
                     /locus_tag="KRM55_000267"
     CDS             37134..38297
                     /locus_tag="KRM55_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1592540.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            38634..40913
                     /locus_tag="KRM55_000268"
     CDS             38634..40913
                     /locus_tag="KRM55_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1592541.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSVVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMLRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRTLCNKYNIPTKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKTLEETNMDSFS"
     gene            complement(41008..42348)
                     /locus_tag="KRM55_000269"
     CDS             complement(41008..42348)
                     /locus_tag="KRM55_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1592542.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAENILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCILNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGININLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(42360..43142)
                     /locus_tag="KRM55_000270"
     CDS             complement(42360..43142)
                     /locus_tag="KRM55_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1592543.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(43157..44179)
                     /locus_tag="KRM55_000271"
     CDS             complement(43157..44179)
                     /locus_tag="KRM55_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH1592544.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(44185..45198)
                     /locus_tag="KRM55_000272"
     CDS             complement(44185..45198)
                     /locus_tag="KRM55_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH1592545.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(45326..46264)
                     /locus_tag="KRM55_000273"
     CDS             complement(45326..46264)
                     /locus_tag="KRM55_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1592546.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            46534..46998
                     /locus_tag="KRM55_000274"
     CDS             46534..46998
                     /locus_tag="KRM55_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592547.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILSGTKTMVIRGAAGRKIPHSRVF
                     ENELLYFMEKGTGKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITSLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(47110..47427)
                     /locus_tag="KRM55_000275"
     CDS             complement(47110..47427)
                     /locus_tag="KRM55_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1592548.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(47440..48171)
                     /gene="chbG"
                     /locus_tag="KRM55_000276"
     CDS             complement(47440..48171)
                     /gene="chbG"
                     /locus_tag="KRM55_000276"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBH1592549.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKSVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(48197..49507)
                     /locus_tag="KRM55_000277"
     CDS             complement(48197..49507)
                     /locus_tag="KRM55_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1592550.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(49584..50897)
                     /locus_tag="KRM55_000278"
     CDS             complement(49584..50897)
                     /locus_tag="KRM55_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1592551.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(50919..51230)
                     /locus_tag="KRM55_000279"
     CDS             complement(50919..51230)
                     /locus_tag="KRM55_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1592552.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(51429..52133)
                     /locus_tag="KRM55_000280"
     CDS             complement(51429..52133)
                     /locus_tag="KRM55_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1592553.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(52224..53585)
                     /locus_tag="KRM55_000281"
     CDS             complement(52224..53585)
                     /locus_tag="KRM55_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1592554.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVTAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLKLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAIYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGTLMISLFISLLKLGKLYK
                     ISE"
     gene            54084..55238
                     /locus_tag="KRM55_000282"
     CDS             54084..55238
                     /locus_tag="KRM55_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1592555.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWVDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(55320..57038)
                     /locus_tag="KRM55_000283"
     CDS             complement(55320..57038)
                     /locus_tag="KRM55_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH1592556.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(57043..58032)
                     /locus_tag="KRM55_000284"
     CDS             complement(57043..58032)
                     /locus_tag="KRM55_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1592557.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(58128..59177)
                     /locus_tag="KRM55_000285"
     CDS             complement(58128..59177)
                     /locus_tag="KRM55_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1592558.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(59454..60122)
                     /locus_tag="KRM55_000286"
     CDS             complement(59454..60122)
                     /locus_tag="KRM55_000286"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBH1592559.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(60128..61501)
                     /locus_tag="KRM55_000287"
     CDS             complement(60128..61501)
                     /locus_tag="KRM55_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBH1592560.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEKTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(61498..63276)
                     /locus_tag="KRM55_000288"
     CDS             complement(61498..63276)
                     /locus_tag="KRM55_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBH1592561.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(63393..63716)
                     /locus_tag="KRM55_000289"
     CDS             complement(63393..63716)
                     /locus_tag="KRM55_000289"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBH1592562.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(63703..64680)
                     /locus_tag="KRM55_000290"
     CDS             complement(63703..64680)
                     /locus_tag="KRM55_000290"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBH1592563.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(64695..65258)
                     /locus_tag="KRM55_000291"
     CDS             complement(64695..65258)
                     /locus_tag="KRM55_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBH1592564.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EKIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(65310..65801)
                     /locus_tag="KRM55_000292"
     CDS             complement(65310..65801)
                     /locus_tag="KRM55_000292"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBH1592565.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(65804..67729)
                     /locus_tag="KRM55_000293"
     CDS             complement(65804..67729)
                     /locus_tag="KRM55_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBH1592566.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVIFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(67731..68042)
                     /locus_tag="KRM55_000294"
     CDS             complement(67731..68042)
                     /locus_tag="KRM55_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592567.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(68672..68947)
                     /locus_tag="KRM55_000295"
     CDS             complement(68672..68947)
                     /locus_tag="KRM55_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBH1592568.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(69062..70471)
                     /locus_tag="KRM55_000296"
     CDS             complement(69062..70471)
                     /locus_tag="KRM55_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBH1592569.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKVSGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMVNLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(70842..71504)
                     /locus_tag="KRM55_000297"
     CDS             complement(70842..71504)
                     /locus_tag="KRM55_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592570.1"
                     /translation="MIDVSIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(71758..73977)
                     /locus_tag="KRM55_000298"
     CDS             complement(71758..73977)
                     /locus_tag="KRM55_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1592571.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLEQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFVAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LSEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIQMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRKHGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(74253..76907)
                     /gene="adhE"
                     /locus_tag="KRM55_000299"
                     /gene_synonym="adhC"
     CDS             complement(74253..76907)
                     /gene="adhE"
                     /locus_tag="KRM55_000299"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH1592572.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
BASE COUNT        25637 a        13460 c         8921 g        29277 t
ORIGIN      
        1 aacatagtcc tatatatcta ttatttggat agaattattt tttaaattag aattatttta
       61 atgaatgatt caagtaatag gtatgaaatt gaatctttta gaactgctta caaaaaatac
      121 tcaaagaaaa atagtaattt tctcagattc acaatatatt ttatatgaaa tgttataagg
      181 taatctattt aataaattta aatttgctat tatagattta gttccaaagt cttactgcaa
      241 agtaatatac atagtttttt aataaactaa taagttcaat taataactac ttaattgttt
      301 aatatagtac atagataact ttaataaatc gacagttatt taaaaaggta gaatcaataa
      361 aattatactt ataaatcttc aatacaataa ttaaaattta ataaaaatat aattgttgat
      421 ttaactgtaa tcttatttaa ttctacctaa cttattatat aaaactattt tttatagatt
      481 ataaaatatc taactttcat ctacttcaaa gaatacaata cttccccttc tcttatagtc
      541 tgcaatactt taatatcttt tattttcata gggtcgattg taagtgggtt ttcatctaat
      601 attatcaaat tagctaattt cccttcttta attgaacctt ttttatcttc ttcaaaatat
      661 tgatatgctg catttatagt aacacccttt aaagcatcta atgggcttat cttttcattt
      721 tctcctattt gtataccttt ttttgtaatt ctattgacag cacaccatac tgtttccagc
      781 atattaggtg ctattactgg tgtatcctga tgaagagtgt aaattaatcc cttttctata
      841 gttgttttaa gtgggctaat cttaaacgct ctatcttctc caaggttttt gatatgaata
      901 tcaccccaat aatatgtgtg agctacaaag tatgaaggta tcatatttat tactttcata
      961 tcatcaatct ggtcttctct tactgtttga gcatgtatca taactggtct tatatgattt
     1021 tcactacttt gctcttttaa gtttaaaact ttctcaaacg catctatcaa ctggtctgct
     1081 gctgcatctc cattacaatg agttaagagt tgcatctttt cttttagtga aatatctata
     1141 aacttttcta cttcttcatc tttgtatata ggatatccac aataaccatc atctgaattt
     1201 tcatatggtc tactcaacca tgctgtctta ccttgtggag aaccatctaa gaaaatctta
     1261 taacctccta ttttaaacct atttatatat ttttttataa actccctatt attatctgct
     1321 acagacttac tttttttcaa atttacatat cctacaacat ccatttttaa tttattttga
     1381 tttgccattg cttttaaaat gttaaattga ttttcttcca ttaaaccttc ttgagctgtt
     1441 gtaataccat agcttagata tatgttctgt gctttttcaa ttgaattaaa aatctcattt
     1501 gatgatggtt gttttatttt agatgctaca ttaaaaaatg cattttcttc taaatatcca
     1561 tttggttctt cactgccttc tactctacct atatgtccac cttctgggtc acgtgtttca
     1621 ttggtaacac caagctgttt taaccccaat gtatttgcga ctcccatatg accagaagca
     1681 tgtgaaatta gtattggatt ttctgaagat gcactatcga gtacactctt atctggatgc
     1741 ttattttctt ctaaaaaatt attatcatat gaaaatccaa ttatccagtc tccttttttt
     1801 atattattcg actctttgaa atcctgtatt ttttttacta tgtctttaaa actggttgca
     1861 tcttctaaag gaactagctt tagagtagta gcaaaagcta tcaagtgact atgtgaatct
     1921 ataaaagatg gcatcaatgt cttaccttgt aaatctataa tttctgtatc tttatttttc
     1981 aaagcaaata cttcttcttt tgttcctatc ttttttatta ttttgtcttt tataagaata
     2041 gcatctccac atattgaatc ttccattgtg atgatatttc cattgtaata aatttttgct
     2101 ttcataaaat tctccttacg ttgtctactt taataaattt ttttcattat tttctgctta
     2161 attatattat cttctttata aactttttct ttagagttta atcatataaa agttttattt
     2221 ttaattattg tttgccaaga agtaaatact attcattgta aataagacaa attaataggc
     2281 tttatactaa ttgaaaaaat attataagtt gctaaattta aatatctaaa ctcaattata
     2341 tctgtacaat tgtaattttt taaatcatga tgtattattt taaatataca gttacattat
     2401 tattcacaat ataagtatct tagttctcaa ataacatctc atgtaatcta ttcaatgcaa
     2461 aaaatttaaa tattttttag gagttttttt atgagcaagg aaaataaaaa tgtaagaatt
     2521 gctgttgtcc aggcgtcacc agtcataatg gatttagaaa aaactgttga aaaagcatta
     2581 ggattaatta aagaagctgg tagaaaaggg gcaaatatcg tagttttccc tgaagcattc
     2641 atacctgcat atccaagagg tctttcattt ggatttgttg ttggaagtag aacaatggaa
     2701 ggtagagaag attggaaaag atactatgat aattctgtac cagttcctag tgctacaaca
     2761 gatttattag gaaaagcagc acaagaagca ggagtatatc tatcaatggg tataacagaa
     2821 agagatggta atgatataaa ttgtaccctt tattgcacaa acttattttt ctctccagaa
     2881 ggtaaactaa ttggtaaaca cagaaaactt aaacctacag gaacagaaag atgtatttgg
     2941 ggagaaggag atggaagtac tcttacagta gttgatactc catatggaaa aatgggttcg
     3001 ttgatttgtt gggaaaatta tatgccatta gctagaacag ctctttatgc taagggtgta
     3061 aaactttaca tagcccctac cgcagattca agagaagagt ggcaagcaac tatgaagcat
     3121 attgctttag aaggaagatg ttttgtaatt ggatgcaatc aatatgttga aaaaaatatg
     3181 tatccaactg accttaacta ctataaggag ctagatgcag aaccagaaat tatgtgtcca
     3241 ggaggaagtt gtatagttga cccttttgga aaatatgtag caggtcctat tttcaataaa
     3301 gaagaaatgc taatagctga tttagaccta gaaaaaatag tacttagtag actagatttt
     3361 gattcagaag gtcactattc aagaccagat gtatttgaat taattgttca tgaataatct
     3421 ttttacacaa acatctacat aaatcttttt acataaaaaa atgagatact cataagtaaa
     3481 tttcaagtat ctcatttttg cttaaaacct ataatcctaa ttataaattt attcacctat
     3541 attttttcta aatcaactac tgttcttcca acatgttttc ctgccattat tgaatctata
     3601 ctatcattta actcttccaa tgatactaca tttaccatat catctaaatc atctaatttc
     3661 cattcatttg ataataaatc ccatattttt aatcttaagt tcattgggca atccacagaa
     3721 tctataccat ataaagtaat tccctttaat ataaatggat atactgaact tgtaaaatca
     3781 acccctcctg cattaccaca agttgttact gctccacaat aattagttgt ctttattgct
     3841 gttgctagag tatttcctcc tactgtatct attactccag cccatcttgg tctaagcaga
     3901 ggtcttcctg agttatcatc cacttctgac ctatgtataa catctttaac acctaagttt
     3961 agtaatactt ctttttgttc ttctaatttt cctgttgaaa ctacaactga ataacctaat
     4021 ttaatcaata ttttagttgc aattacagca actcctccag taccaccagt gactaataca
     4081 tctcccatat tcttgtctac agaatctata aatttataca cagataaagc tgctgtaaac
     4141 cctgctgtac cataatccat tgcttctttt agtgaaagat ttttaggaag tttaactacc
     4201 caactagaag gaactcttat gtattctgaa aaaccaccag aagtattcat tcccaagtca
     4261 taacctgtta ctaaaacttc ttctccaatt ttaaaatcat cacaactact agattctact
     4321 ataccagatg catcaattcc tggtgtatga ggatactttc tcgtaacacc cttattacca
     4381 tttgcagaaa gtgcatcctt gtaatttaga gaagaatatt ttacttttat tagaacttca
     4441 ccttctggca atgtatctac ttctctttca actatatttc ttctaaaatt tccttcttct
     4501 tctgtaatat atagtgattt aaatttttta ttcataaatt tcctcccaat acatttagtt
     4561 ttatgttaaa ctaattatag tttataaata gttttatgtc aaactaattt aaatagatta
     4621 aagattggag aataatttat ggaagataaa tatattgtac atttcataag taaaacaaag
     4681 gctagtatga ttaaattcat tgaaaataaa ctcagtaaaa atggtttagg tgagttaata
     4741 cctactcatg gaaatatttt aactgcactt tatgaaaata atggaatact tacaatgaaa
     4801 gaaattgcag ctaaaatagg aaaagataaa tccactgtta cagtgttggt taataaactt
     4861 ataaacctag gatatttaga aagacaaaaa tgtacaaatg acaaacgtat cacgtatata
     4921 aagcttacaa aaaaggcact gcttatagaa gatactttta atagcatctc aacacaagtt
     4981 aaagagacgg catatcataa tattacagaa aatgaaaaac aagaatttct tagaatttta
     5041 aaaaaaatta atgataattt taaaaatgct gactaaattg agcataatta tatctcctat
     5101 tggaataata aataaaaaga atcaaatatt gtaaaaattt attgtgatag agaggtagaa
     5161 tatgaattta aaagatagta aaactaaaga aaatttatta agagcttttg caggtgagag
     5221 tcaagctaga aatagataca atatttctgc atctgtagca aaaaaagaag gattatatat
     5281 aatagagtct ttatttaatt acactgctga ccaagaaaaa tcacatgcaa aacaattctt
     5341 ttctaaatta aaagaattta ctggtgaaaa tataagtata tcaggagcat accctgtaga
     5401 tttatatgac aagacagcac aacaccttaa agctgcacaa cataatgagc ttcaagagtg
     5461 ggatgatgta tataaaaact ttggaaaaac agcacgtgaa gaaggatttg aatctatagc
     5521 taagttattt gaaaatatag ctgaaataga aaaagttcat ggtgatagat ttggtagata
     5581 tgctactgat ttagaagaag gtactttatt cagaagaaat gaagatatac aatggatatg
     5641 tacacattgt ggccatatac atataggtaa agaagctcca aaagcttgtc ctgtatgtct
     5701 tcatccacaa ggatatttct tagattttaa aaactcatta tttgaataaa ttaaggcaat
     5761 aattctattt aaacaattta ctatatttat atcaagtatt tttataaata ctgtattatc
     5821 ttaataacaa taaaatgaac cattgatatt actataagta gaaaatgtag tttaaataca
     5881 atttatagta gttcatcatg gttcatttta ttgtttacta atccctataa cctacttaaa
     5941 tctatcttta acttttacac actcacataa aatctcatct ttaaactaaa tatttaaata
     6001 aagtgtattt taagtagatt attataatac attatataag ataatacact atgataactt
     6061 tatacttata tcatttattt cttttgtcaa gtcaacctca ataatcttaa ctacatcttt
     6121 ttcaaacttt acttttttat aatccagaca tcctactacg aatggaactc caaactttct
     6181 aaacaaataa atctttccac tttcattgta tattgatgta aaattttctt ctattatatt
     6241 tactatcaat tttaactctt caaaagttat tatagattta actaaaaact tctctattat
     6301 gctcaatata agcagttctt ttttacctat gctttgctct tttttatata aattttgaaa
     6361 tatttctttg gtataattac atataacttc tttacttaga ataaaatcaa tgtcaaattc
     6421 tttattaata tcctttttca taaacatatt tgcaatatca tcaagagaag tctcttcttt
     6481 catagacaat attaactcta ttctttctag tattttatct cttggaaaga aagtctcttg
     6541 acctgtaaaa gctgattttt ttataaacca ttcctctggt attatgtttt ttcttttcca
     6601 tctatataat tgaccataag atatattagt tttactcaat aaatctttct tagatattaa
     6661 ttcttccata acttttctag cccaccttta tactgttttt tacagtagaa ttatctgaaa
     6721 ctgataaatt atcactgtat tcaatatttc caacgtcaca attatctact agagatatgc
     6781 ttttacctcg tatatctttt attgatgcat cttctaattc aatagtatct ccctctatca
     6841 aattacattt aaactttcct gaaaaaatat taatgatttt aattaatgaa aaagcatctt
     6901 tgcttcttcc tatttttata ttagttgccc ctatctcttt acaataagaa cctcctcctg
     6961 aataaacata tatattttct ccatttaaaa gaccatcaca ttttattact ccatatacct
     7021 ttatatcttc acattctata tttgatttat ttctcatttc gccatagatt tttatatctt
     7081 gtgcatacat attttcattt acacttaatt gtcctcttat tgtaacatta ttacatttaa
     7141 gtttgccatc cactttctgt tgagcagtta taactaagtc atctatttct gcatctccct
     7201 ctatattaag ttgaccattc actcttacac gctctgcttt aagattgcct cttataatag
     7261 tttttccgtt aacaacaaaa ttttttatat tgatgtcacc ttcaaatttt gcatctccaa
     7321 ggacttttac ttcgttactt ttaacatttc cttttgattt agaacttccc acgattttta
     7381 tattttcata ctcaccacta cttataaagc cttctccaag tatttttata gacccttttt
     7441 ccatattatt acctcatttt aaattttatt tttaaaccta cttattactt atccttcttt
     7501 aattttattt tttcacttat attctttatt tcaccaacta ttgaatcttc atcaatctct
     7561 atactttcac tgtactccaa actttctaca taacatccct tgcctatttt aatatttttt
     7621 cctcttacaa ctttgacttc actattttct aagcttattt catctgcttc tataatattt
     7681 gcaaacaatt tactttctgt atactttcta attgataata gacctaaact tattaaattt
     7741 gaagacactt tttcaaagtt gatatgcttt ttttctagca tacgaaattt tttgcaataa
     7801 tctccatgcc ccttttttat atttatacta cttgctccaa cttcattaaa attagaagtt
     7861 ccatttaaac taatattaac ttcttcacaa ttcaaaaatc cattacactc caagattcca
     7921 cttaaattga tattttcaca atctatattc tcatttgctt ttaaatatcc ttctccatga
     7981 ataatatccg attttatact tccttctaca ttaataattc cactagtatc aatttcaaca
     8041 gaattaatat ttcctgtaca tctaagaagt cccgatatct caacttttga tgccagtatg
     8101 tttccttcta ctttacttaa accagatgta aaaaattcat tacattctgt tgtcccaaaa
     8161 acttttgctg aaccagaaga atcaaattta ctacatttta cacttccttc tattttgcct
     8221 gttcctgata tattaacatt atcaaaaatt ccacctttac attttccaac accatcaaat
     8281 cttagtgaac ttaattcttc attcataatg atatcctttc tttaccgtat tttatcttta
     8341 aacctaatat aacaaaacat tgttacgttg tcaagtatga taataatact taataaagca
     8401 actatcattt attttctata aataggcata aaaataatag ggaaatgctt tatttaaact
     8461 ataaatctaa tttcttagat tgtggtttaa ataaaatata tccctattac tcaatgttta
     8521 tatattcatt gtataaactt ctaaaatata agtctttaaa ttctactgtc aatacttttt
     8581 atacactgtt tgtgctatca tctcacacac ctaaaggagt aggctttgcg cactattctg
     8641 taacctacaa gacactatct tcttctatct attgataaat ttttctatta catcagctag
     8701 tctctccata tcagttggat agacttcacc tatgctacct attctaaatg tatctatatc
     8761 agtcaattta cctggataga taacaaatcc attatctttt aaataagtat aaaattccat
     8821 aaattcaaac tttgcatttt taggatataa gaaagttgtt attacaggtg attgagcatt
     8881 atcattcacc aaagtatcaa agcctaaaga ttttaatctt gaagctattg taaactgatt
     8941 ttctttatat ctagcatatc ttttttcaac agaaccttct tcttccaatt ctaataaagc
     9001 ttgataaaaa gctcttacaa catgtgtagg tgaagtaaat ctccatttac cattattttt
     9061 ctccatagtc tcccattgcg catacacatc aagagataat gatttagcta tacctttaca
     9121 tttagataat ttctctttat tagctattat aaaaccaaat ccaggtactc cttgtataca
     9181 tttgttagaa ctactaacta aaaaatctat attaaaatct tcaacatcaa tctcaattcc
     9241 cccaaaacta ctcatagcat caactatata aattttgtta tattcttttg caagtttccc
     9301 tacctcttgt ataggattta atctacctgt agtagtttca cagtgaacca ttgatatatg
     9361 tgttatatcc ttgttttctt ttaataaatt ttctactaca tttaaatcca ctgcttctat
     9421 atctttaaat gtgcagtcaa caaattgtat gttaagataa ttacatatat ctttcattct
     9481 ctttccatat gctccatttg caattacaag aagtttacca tcttttgaaa tagtacttcc
     9541 tattatagct tctactgaaa aagtcccact tccttgcatt aatacacttg tgtatttatc
     9601 tgtattttgg gttgctagag atactaatct tcttctaaca tcttgtacta ggttattata
     9661 ttcaacatcc caagtacacc aatcttttaa catagatgct cttactgatt tagtagtaga
     9721 tagtggtcct ggtgtaagta atatgtaatc attttctggt acaaaatctg atttaatagt
     9781 ttcattctct atttttatta gtatatcttc taactcagcc atagtttcta ttacaaaatg
     9841 tgcacctgcc tctttaaatt tctttgaaac tatactcatc ttagctttta attcttcctt
     9901 atccatgttc tctacttctt cttgtgtaag ccctaactca cttgaacctt ttattacagc
     9961 aacactccac attcctgcat ttacgccttc ttttacatca cttattgtat ctcctacttt
    10021 taccatagaa ctcataggag acacccctaa agcttcagca tttttatagc acatccaagg
    10081 atacggtctt ccttgagata cttctgatgg tgttacaaga aaatcgggtg agtatccctt
    10141 ctttgctgca tttggttcaa ctatgttcat catctctctt gtataacccg ttgtagaacc
    10201 tatttttaat ccattttttc tcaacttttc aatagtttca acaacatgag gaattggagt
    10261 cgtatactct tctaatgtct caaataacat tggctcaaat tcagcataaa gttcatttac
    10321 atcatcttca gttggcactt taccaaactt atctgaccaa atattcttta ttctatccat
    10381 ttcacacatt tctcttatat ggtctatttt taattttccc ataggttttc ttgcttcttc
    10441 cattgttaca tctatacctc ttcttttaaa tatctctata aatacattaa gaggtgcaaa
    10501 acatccataa tctactgttg ttccagccca atcgaatact actgctttta ttttttctcc
    10561 atatatcttt ttcatattta tagcctccat agattctttt tagaattttt gtgtttttaa
    10621 ttgtttttac ttttaaagta taactttcat atgttaatta tacatcatat ttaggttaaa
    10681 tatatattaa atttctgttt ttagttgtat ttagttgttt ttattttgta tcatattccc
    10741 ataaaatcct aagttacaat ctaaaattta ctttctaatc ttaatctatg aactgactat
    10801 attttatgaa tttagttgta ttgagcatag ttgtattata taaaactaag ggtttatttt
    10861 gcttctatcc atgttatatt tatctcattt aacttatcct tccattcatt cggaggttct
    10921 acatcacaaa taacaaaatc taattcctct aaatctgcta tcttatacat actagcaatt
    10981 cctattttag aactatcaca taatacaaaa ctttcctttg aattttttat atattctttt
    11041 gacaacaatg ccttattttg gtctatacta ctaattccaa aactatcaag tataccttca
    11101 ctagatataa aagctttatc tacgtataag tttttcatag tatctattga cattggacat
    11161 gctgtccttt ggtgttttaa atttactttt ccaccaataa atataacttc tccatcaaac
    11221 aaaccttgat tctcataaga aatcaatttt gatagaactg gataagagtt tgtaataatt
    11281 tttaaattgt ttacagatat tatataatct acaatctgca aattggtagt accttcatct
    11341 atgataattg actcattgtc atttacaaac ttagctgcat atttagcaat actttgcttt
    11401 ttatctaggt tagtattgtt tctctttata tgttctggtt caatcactcc ataatttatt
    11461 tttatagcac caccatatac cttttttaat ttattttcat tttctaattc ttccaaatat
    11521 cttcttattg tttctgatga tacttctaat ctttttacta attctttagt gtttaccttc
    11581 ccttttgaat ctaataattt aagtatttct ttttttctat ctatcgaatt taaagacatt
    11641 cattttcctc ctaaatataa tatatttttc tcctataata ttacaatgat acctaagatt
    11701 tatgaaatca tatttatgta ttaaattttt tacttaatta aagttatttt caaaagactt
    11761 tgtattatca ttaaaaaagt ccatcaaata ttagtatcag atggactttg taaaatttta
    11821 ttttataaat taatatttaa agtctaacta ctaatttatt ttcttgtctc caagaatttt
    11881 actaaattat ttacagtaga catatctttt ctctctaaat cagttggttg aagctctatc
    11941 cctaatctat tttcaatttc aagtaaaact tcaattatag ctaatgagtc taaaagttcc
    12001 gtctcaaata aattaaggtc taaatcttct cttatctcat cagtccctaa tacatcttca
    12061 aatatttcta taactgtttc ttgcataaat tttcctcctt aaaattaagc taaataacct
    12121 gagaatatca gcaatccaaa acacacaata tggaatgtaa tgaaaatctg cactctctcg
    12181 aaccatttat cttttttatg ttttttataa aatttagatt ttcgctgata tatatcagtt
    12241 aacacaagtg ccaatccttg gtatacacca taagcaacat aataccaagt tagaccatgc
    12301 caaaatccca ttgttatcat ggttatcatc tgagccacat gagcagcagt agtccttttc
    12361 ttaaatcttt tctttctcat tgatgacata acaaatctag aaaaaatata atctccaaac
    12421 catcttgaaa gacttatatg ccatcttgtc cagaactctt tcatatcttt actgataaat
    12481 ggcttgtcaa agtttatagg tacttgtatt ccaaatatgt accctgtacc tatagcaaat
    12541 aaactatatc ccgcaaaatc aaagaacagg tataaactat atgcgtacat ataacttaaa
    12601 atatttataa aactcatatc tttaggtatt cttgataccc aatatgtatt tatcaaaaat
    12661 gctataacaa acttataacc tactcccatg acaatatttt ttattcctgg cagtaagtat
    12721 tcttctatat actcttttct agagatttgt ttttccaagt cctgttcaaa tcttcttgac
    12781 ctatcaatag gtccagaact taaagttgga aaaaataaca taaaataaag catctttgaa
    12841 attttaactt cttttatagc tccatcataa atttcaataa ccatttgtat agttctgaaa
    12901 tttaagtatg atattccaat aaatccaatt attccaaaag aagtaactgg agatatttta
    12961 tttattatta ttgggagcat tgatgcaaac aagaatcccc aatatatgta tttattttta
    13021 gtttttcttc ttacatattc atatccttta actattatta cttcaagaat aataaatatt
    13081 accaagtact ttagttggac atcaattcct actattaaga atatcataaa caaacttgcc
    13141 aacataccat aatactttat attcttgccc attagaccta aaattactgc tggtattgat
    13201 gttaataata atatataaag ataaaaataa tctccatact gtgaaaaaat cattaaattt
    13261 cctccataag tttctttctg tctattttac cattgatatt tgttggaaac tcagagatta
    13321 ttgaaatatt tcttggaatc atatatgaag gtatatactt tccaagttcc ttttttatta
    13381 tcatcccatt tttaatatta cttaaatcat tcttttcatt taactcaaca atacctttta
    13441 agtaagcaat tttttcgtcc ttatacactg gtaaaactac tgcatttttt acattatgta
    13501 cttttctcaa attattttct atatcttcta tttcaattct aaatccattt aatttaatct
    13561 gaaaatcttt tcttccacaa taatatatat ttccatctaa aagatatccc atatctccag
    13621 ttttataagc tctccacttt acaccatcta tttcatcata gaaaaatact tcatcagtct
    13681 tttctttatt attgaagtaa cctttagaaa ctgatggtcc aattattata atttcaccct
    13741 tttcattttc tttaagctca tttccatctt catcaagtat ttttatttta caatttgaca
    13801 tagggtatcc aactggaaga cttttttcat catctatagc cttttgagtc atatcattta
    13861 cacttacacc aacagtagcc tcggttggtc catatccatt gataattctt gtgtttggaa
    13921 atctactcat aagttcttta gtaagatttt ttgaaagtgc ttctcctatg aatatcattg
    13981 actcaaggtt aggaagcatt ttactattaa actctttttc agttatacat actcctgcaa
    14041 aagaaggagt tgacacccat acagctatat ctgagatact aaattgtcta aatagttctt
    14101 tatagtctgc taatacatct tttgatattg aaaataatgt agctccatgg ataagaccag
    14161 ggtatattgt tgtaactgaa aggtcaaaag aatatgctgg ttggttcatt attacttttt
    14221 cacttccatc tatgtttaga tatgggctta tccaatctga aaagctatct aaattgtttg
    14281 aacttatttg aacccctttt ggctttcctg tacttcctga agtaaatagt atatatgcat
    14341 tttcatcatc ttttacccag ttttctttat ctaatgattt tccctgatat tcatttatta
    14401 tataatttaa tttatccata tcaattacat tgatatctcc aaaatctttt tcatcactaa
    14461 agttaaataa tacctttggt tttatctctt tagtgacttc aaaaactcta tcaattggaa
    14521 aactaatatc aagaggcaca tacgctctac ctgattttaa agctcctatc atacatgcca
    14581 ttatcatgtt ttctttattt ccataaatta ctataggagt atcttcttct ttgtatacat
    14641 cctttagaaa tactgatata gcatctgaat attcatttaa atctttataa gaaagtttat
    14701 ctccattaca cattagtgct gttctatctg tatttgaata tttttttatt ccttcaataa
    14761 ttttcatata agaatgctcc tttaaaatcc gttataaata aatggcaatt ctttaaatgg
    14821 agtaaatgtt agaactccta tcgccaatat tataaccata gttaaacaaa tactagttaa
    14881 caaatcttta ttgttcttta aatattttaa ataatctctc acagacatct acccatcctt
    14941 tcgtaccaag atgcattaca tcccttaaat aatacttatc tgacccttta tctttaaggt
    15001 ttagaacttc aaagcctttg ctttctgcta ttttttgtgc tttatcgtag tactgatttc
    15061 tttctttttc agaaatacca gtcaaattat agaatttatc catacttgga attaatacaa
    15121 caactggctt aatacctaag tcagtacata catttagcat cagtttataa ttttcaaact
    15181 ccttagatgt taataaattt acatctttgt ctcttccttt gtattgctct ataccatctt
    15241 taaaatgctc tttataatag tacttatcaa tatttagtgg atttttacca actctttttt
    15301 tagcatcttc aatggctttc tttctctcat atgaccaatt tattggtctt tttctttttg
    15361 ttgctctctt tttatctagc ttaattaatc gtttataaag aatacccttt tctttaagag
    15421 ctatacagta ctttcttcct tgaaaataag gctctaaaag caccttttca gctttttcag
    15481 gaaatgtctt aggctcatat agcttagcat ataatgcttc tgctttatac tcgtcacttc
    15541 cccataataa cttacttgat ttttttgcat attcaatctt attttgttta gatatttttg
    15601 gattatctaa aaatcgataa aattgtattg gtgaaaatct agactgataa tggtgacttg
    15661 tgactccgtc tttttccata aaccattgca tagaaattaa caagacaact ttcttattat
    15721 caatattagg attcatactt cctaatattg cagcatcttg taatgtctga gtataggctc
    15781 tcccaattgc aaacacctta tttttactcc tatttgtatt aaaatagtac tttggatgtt
    15841 gttttgttga attactaagt tctgatgacc ccaaaatcat aatatccttt tctcttaaaa
    15901 aatgattatt tgctgtaacc cctttatctt ttatatcact taaagtatca tccataattg
    15961 gaagtagatt tttctccctc aaaagttcat cagttttaga atcaagaaat ttgtctaacc
    16021 caaataaaaa tactacgcct attataaaag gtgtaataaa gtatatcaat tttctcatat
    16081 tttctctcct ctaaaaatat tcaaatttat gttattatta atcatattag ttttgatatg
    16141 tatattcaac tacaaaattg taataaaatc gtcaaaactt tttttgatac tgttacaaaa
    16201 ttgtaaaaaa aaagaaaaaa acgccaaaaa taaatttctt tttagcactt tttcatactt
    16261 ataatttgac attttaacac ttggctaagt atacacctta ccttaactta aaattaaatt
    16321 tatttaagaa tatatattat aaattcttat attttctaat ataaactata tactatcagc
    16381 tggataaaca atactacttt gtcttcttat ctcatccata atttccatta ctattattga
    16441 attttcatga gaatttatat ttgattctat tttattgtta tttataagac ttataaactc
    16501 tacaagttca taatacattc cttctatttc tctaggcttt tcctctgctt tttcttttgg
    16561 aatagatata tcttcttctc ttccatctct gtatttaata atagcttttt caaatagatt
    16621 aagcttttca attattatac ttccctcttc tccttgtatt tcagatggta tataagaatc
    16681 agctacttta gaatactgaa ttatcgcatc catatcatca tattgaaata cagctgaacc
    16741 ttctccatcc actccagttt gaagtatatg agaaactgcc tttacagttt ttggagcacc
    16801 aaataaattc accataggat gtatacaata cactcctata tccattaaag ctccatttga
    16861 caactctttt ttaaaggcat tttctataat tccattttta tatttatcat atcttgaaga
    16921 atactgacaa tagcttccaa aaaatcttct tattttccct attttatata agttttcttt
    16981 aactgcttta aagtttggaa cacatgtaat tctcatagct tccataagca atacattatt
    17041 atctttggct gtttttatca ttgatttgac ttcttttaaa ttagatgcta acgacttttc
    17101 acaaagcaca tgttttttgt gttttaaaca agtaatggct tgctttgaat gtaatgcatt
    17161 tggagaagct atatatacag catctatatc cttcgattta gccatttgtt ctaaatcatc
    17221 aaaaaaaata cttgctccat atagagttcc aaattctcta gctttttcta aatttctaga
    17281 atatacagca accaattcaa agtctttaac cctagatgca gctcttagaa atatatttgc
    17341 tatattgctt gtcccaacaa taccaaatct tattttaccc atcataaatc actccccatt
    17401 ttctacactt tattttaatt ttaataaaaa actttacaac ttatagatat attataaaat
    17461 aattttatca aataaaaaag aaagctaatt ttaaatgatt tcaccatttt aacatagctt
    17521 tcttttaact acaatctaaa ttcaacttat atttttaaag ttatctttct actatatctt
    17581 tatttcccct caaaaatttt atagtaagaa tttcatccac aaacaatgtt actaaaagta
    17641 tagttacaac aattggccaa taaggtatta taagtctata taagctatca actatataca
    17701 cttgaaaata tctaactcca ataaatgtca atatagtcca atatacagaa aactttagac
    17761 atactattcc tctactattg tacttataat ctgaataatc ccaatagacc ttattaaaat
    17821 atactttcat aagtattccc gtaatatatt ctactactgt cggcactact agacataata
    17881 aaagcaatgc aaatatatta ttggggtcaa taaatcttga gacctctatt ataatcgaca
    17941 ttgcaattgc atacattggt ttaaatggac catttaaaaa tccatcttct tgaaaatgcc
    18001 cttgtttata ataactatat aagttttcaa ttatccaacc tataaaacca tacaagaaaa
    18061 aattaaataa aaaatataat agagaaccta cattatccat gaatattcct cctagctgtt
    18121 tatacttatt ttttctcata ttcatggatt tattctaaat caaagaaatt atatttaatt
    18181 tatttaatta atactttata ttatagattg tgacattctt tagagtttaa actttttagg
    18241 tattctctaa cttccagtaa attttcaagt atcttatgtg attgtgattt aatttgctca
    18301 tctggctctt ttaaatctgg tacatttata catcttatac caccattgta tgcagcttca
    18361 actcccatag gcgaatcctc tatgacaata caattttggg gattaacatt tatcttttta
    18421 gctgctttta ggaatatctc agggtttggt ttagagttta caacatcatc tccacaaact
    18481 atagcatcaa agtaatcttt taaatttgcc ttagctaatc tctttactgc tctttctctc
    18541 tttgttgatg ttgcaacagc cattttgtat ccattttctt ttaaaaaaga gattagttca
    18601 ttgactccta atttgatagg agctcccttc ctctccataa attcaatcat gtttttagtt
    18661 ttttcgtcat ataaatctat tattggtaca gaactatcgt atatatctgt aagaccttct
    18721 attattcctt tacgatttct tcccataact gatgtataaa tttccttagt catagtatat
    18781 ccatactttt caaacgtctc catccaaaat tcaagagaaa ttctctctga gtcaaacaaa
    18841 actccatcca tgtcaaaaat aattccttct actttttgca tacaattcct ccaatatttt
    18901 ttgatataat tatattacac tttttatgat taattttaca accctcaatt tatccaattc
    18961 taatattgta aaattgtaat tttcaaaagt tacactttgg tttactttaa tatttgaacc
    19021 aagcatatag gatatccacc cacctatact gtcaaatcca tcatgctcta tatcaagtcc
    19081 aaaatactta ttaatatagt tgatagattc agttccatca actaagtaag aacctgctcc
    19141 tattttctta atatgagtct cttctttgtc aaattcatct tgaatttctc caactatctc
    19201 ttctagtata tcttctattg ttaccacacc agatgtacca ccatattcat ccacaactat
    19261 agcaagttga agtttttcct ttcttattct ctcaagagct ttatctatag ttaaattttc
    19321 agatatatat ataatatctc tcaatatttc ttctagttca attttatttt catttatttt
    19381 ttgattgtat aaatctctta tatgtacaaa acctaatata tcatctttat tttttctgca
    19441 tactggatat cttgtaacac cttcctcttt taaaatagct aatatctttt cttcagaatc
    19501 actttcatat atacatacca tatcagttct aggaaccatt atctctctaa ttttcttttc
    19561 ttcaaattca aaaatattat caactaatct ttgctctgat tcatctataa gtccactttt
    19621 ataactttct tctactaata gtcttatttc gtcacctgta tggggttcat caacctcatc
    19681 agcttgtgaa tatccaaatg gtttaagaaa taaatcagta cttaagttga aaaaatatat
    19741 tattggatat gttaacttat aaaatcctac taataaaaaa gatgtactca acattatttt
    19801 ttctgtatta taaagtgcta aagctttagg aaccaactct cctattacaa cctccatcat
    19861 tgttataatt aaaaaagaaa tggaaattga tatagtatat ataatacttt cactaagatt
    19921 aaatacactt actattggta aaattaactc tttaactgta gattctccca tccaacctaa
    19981 tgcaagtgaa caaagtgtta taccaagttg acatgcagaa agataggaat ttaagttgtc
    20041 ttttattatt ttacatcttt ttgcattatt attaccttca gttatcatgg tatcaatcct
    20101 agaactacga agttttacca tagcaaattc acaagctaca aaaaaagcat ttatcaaaac
    20161 aagcattact ataagtgtta cttttaataa ctcccgcata aagtattggt tcttataatg
    20221 taagaaatct ataagaactc aaagttcccc ccttatatta ataaatttaa tttataatat
    20281 atattctatc atatttatta atatatccta ctttattaca aataattttt ataaactaaa
    20341 taaccccttt taatatttat gactggctat ttgataaata ttaaaggggt tatttagtta
    20401 tcatttttta tttctaaaaa tcttttctca aatgatttag ttatctattt atccaatttt
    20461 ttacataatt taatgattaa aaatattaat tttttcacta taaagtacaa atattatctg
    20521 attattaaaa taaatattaa tactataaat aaaaacgaag catgattttt atttaaataa
    20581 atctcaaact tcgtctttac ttacttagat atttatttac tttctaaatc ctattatttt
    20641 taaaacctta tctttttaat acttcaccac atttattctc agtaatctct ccattttcca
    20701 atgcaatttt tccatttaca attacatatt caacaccatt ggctagtaat tgtggctttg
    20761 aaaaatcaat atcttctgac ctagaataac tatagttatc catgtcaata actgctatat
    20821 cagctatcaa cccttcttta agaatacctc tattttttat tttaaattgc ctagctggta
    20881 atgaagtaac tcttcttaca atctcttcca atctaacacc agactttctg tacatattga
    20941 agaaaattgg aaaagctcct cttctttgta gttcaaacca tgacatatcc ccacccacac
    21001 taaacaaaca atctgaacca accataacaa atggattatc aattatttta tcatcatgta
    21061 gtttatctgg gaaatcagct ctatacattc ctcctaaaca aaagataagt tcttcgtctc
    21121 catctaaaag taaatcgagt aataacttgt cctcatctat tcctttttgt gtagctattt
    21181 cacgtattga tttcttttcc atattaatat ctttagtgtt tagaagtatt atactccccc
    21241 tatctccaag tataaatgct tcttttaata taagtgttct tccctcttca tttctaagag
    21301 catccattac cccatctata cctaattcaa atagactaga tgatattgcc ataataaatt
    21361 gaattactct ttttttcttc atacaatgcc cagaacttct tggtactgtg tcaaccatta
    21421 tttcaacacc attataccta gcctttaata tctcatcaaa tgcttctatt tcaactggac
    21481 ttaagtgaga tacttgaacc ctagcaccac ttttttgccc aacctctatg gcttctttta
    21541 ctgcattata tcttcctatg taatctctaa tatgagatgt atatatacca tcatactctt
    21601 taatctgcct tgcaatatca acaagttcat caatatcagc atacttactt ggtatatatg
    21661 ccaatccagt agatattcca aaagcaccac ttttcattcc atcatttatt atatctgtaa
    21721 tttcattttt ttccttttct gtaggaggtc tatccttaga acctcccata acactccatc
    21781 ttatagtccc atgccccaac aagaatccca tattgacaga aataccactt ttagatataa
    21841 ggtcacaata ttctgtaaaa ttattccaac atttattttt atctataaga tacttttttt
    21901 cttcttcaag taatagacca tttttataca tatattcata cacattttca gaagaatatg
    21961 gtgttataga atgtccacaa ttaccattta tagttgttgt aactccttgt tttagaaact
    22021 tttcaaattt accatctagt attgctacta tttcttcatg aacatgaggg tcaataaatc
    22081 caggtgttat aacttttcca caacaatcaa tctctttatt tgtattgcta tttatcttag
    22141 aatctatttt tgctattaag ttgtctttaa ttgctatatc tccataaaaa ccaggattac
    22201 ctgtaccatc tattataaat ccatttttta agattaaatc atatatcaaa atattccctc
    22261 cttaaaaacc aatttttaaa taatcttaat gtaattttta tatttgaaaa tcaaattatt
    22321 aaatttcata tttgaaaatt cactattatt tcattgtaat tagtcactaa gcttatcttt
    22381 atacatagct cttgcaatta atatagtacc aaatacacat ataagaacta ctagagactg
    22441 tggtattata ccttgctttg ataatataat agtcaataca gatattacaa ttgctactag
    22501 acctaatttt ttatcttgta aaaatacttg tccaaaaact gacccaaata gagctggtaa
    22561 aattaagttt aatttttcta ctacttcagc tggaatttta gatagtacgc ttcctcctaa
    22621 aattacccct atagttagta tacttatatt cactaaaata gatacagcta ttcctattgt
    22681 agatattatc gagccttctt ctgtacctga ttcaacttct gctgcctttt gagctgctat
    22741 tgaacatggt agcctcatat tagatatatt accagaaaga aaactcatat aagttcctgg
    22801 tatacctaag attggtgaat aagaaactgg ttctattatg taatttggag cactcatact
    22861 gacaattgcc attgtacttg ctaataatgc tgatattgga ggcataatac caaatccaaa
    22921 gctcaaaatt attccaggaa ctaatgctgc tataataccc aaagatagtg ttagtcttcc
    22981 ataccttatc ataaaaggta aatattcttc attgtatata gattttactt tactcataaa
    23041 actcccccct tatattactg aagctattat cattccgcta aacattgata ttgtaagccc
    23101 ccactctctt aaccatttta tatttttctt cttttcaagc atacacagta ttaccattat
    23161 agccattcca cttatacatg caattgttcc attatcaaaa cgcaacaccc tatcagcatt
    23221 tagatatgca aatgaaccca acattgctcc tagagatatt attggtataa atgatttctt
    23281 gccactagat ataacattgg ttatcttatc tagtttatgt ccaaatagta atgtgaatat
    23341 tatccatcct aaagaaccta atatcatagt ccaaactgca tttgtaaatg caagttttgt
    23401 catttcagga gaacctaaag ttatacctaa tgcatctgtt ccaaatccgg ctgacattga
    23461 ttcaaaaatt acagaaccta taaatgataa tctcatccat gctataggcc cacccatagt
    23521 tactataagc gataccattc cagcaaatat agtcattgaa ggcccaatag ctgaaatagc
    23581 actactctta acagctgact ttatttgttt atctgttatt cccattgttt taccaacttt
    23641 gcaagatttt atagcaaata taagggattg taccactact attgatactg ctactgtact
    23701 cgctatccac aaaagtggat gattagctaa ttttaaataa tccatttata aaacctccct
    23761 ataaatcctc aaattttatt aatatttcta atatatctat ttccaaacct gttttagtac
    23821 tctaagtata tttccaccta gtaccttctc tatttcctca tcactatatc catgctttac
    23881 taaatatcta acaatgtttt ttgaagtttc tgttgggttc tcaagacctt ttacatattc
    23941 tactttggga tgttcttttg ttcctgttat tttttttata tcaaatttag cagctagtac
    24001 tgagtgtaat tttacatggt cgccatatac tgtatctggt ccaaaagcta catggtctat
    24061 tcctactaaa tttttaatat actcaaaatg ttccataaat gactctattg aatgttcttt
    24121 attcttctct gttattgtag tatgaggtgc tgcttctaca cctataaccc ctcctttttt
    24181 agcacatgct attaatactt catctggagt tagtctcttt gtgttccata aatttcttgc
    24241 cccaacatgg cttaatatta ttgggtcctt gctatattct attacatcaa gtgtagtttg
    24301 aactccaacg tgagagcaat ctattgccat tccaatttta ttcattcttt caacagcttt
    24361 tttcccaaaa tttgtaagac ctccatcttt ctcttctttt agtcctgaac ctaatgcatt
    24421 ggattcgctg tatgttatac ccattaacct tataccaaat ccatacagta tatctattct
    24481 atcaagttca ttttctattg gtgctgcacc ttctaatgtt ggtatcaatg ctactttacc
    24541 ttcactttta gctctgtata tatcttctac tttttcacac tttatgacaa aatcttgatg
    24601 agctaaatca cataatctca tgcctaaatc tattaatata tcatcccatt tccaccctga
    24661 atttgatgtt atcgtacata caccatccat taaattatca aatatagcat cataatatcc
    24721 tcttgataat gcttcataag cacatctttg tttaccttcc ctattatatt caaatatatc
    24781 tctttctagg tgttctggaa ataatactgg atgttcatgt aatgatataa atattttttc
    24841 atccactata cttttaacct tagcttcttg aatatcatct aattcaataa ggtattcttt
    24901 aactctttta tctcctttac acatctcaat agatgaaata tcttttcctt tttctaaata
    24961 actataggct tcatatcctt tgtaagctga cttcataaca acatcctcca agttctacaa
    25021 ttttttatat ttttcctatg tagcaattga tgtgccaaaa tataaatttt aattgtataa
    25081 taaatcttgc aaaaaataaa aacagtagta aggttgatat ttactactgt tttattaaaa
    25141 ataatcttct tagattattt attcaatatt tttgaattat cttaatctta aagataattt
    25201 tatttatttc tatccattat agggattttt ttagggtgtt ttgccttttt agtcccctat
    25261 atcactccct taatttttac atatgatata aagttctttc cttcatcagt tataaaacta
    25321 ccttgttttt ttactccaga taaaagtaaa ccatggctct ttaacttatc tattcttttt
    25381 ctaatttggt ctacacttaa aactatatct ttttctttta aaatctcttg cagtttattt
    25441 cttcctaata atatattttt attattccaa gtttctatac tggtcaatat acatatactt
    25501 tcctcaaaga aattagattg tttgaaatct aagataattg aatcgaaatt ttcattaact
    25561 aaagtattgt ttttttcaaa tctaaattgt tctggcaaat gctcgtaatc tactctatct
    25621 tcctcaacta tagtatcaat ataataaatt aaatttttaa gctctcttac atttcctggc
    25681 cattcataca atgttaaagc ttgcattgat tcctctgtaa aacatttgtt gctatttatt
    25741 tcatctaaaa aatacttact tataagaggt atatcttcct tacgttctct aagtctaggt
    25801 atctctatat gtaatacatt aatcctataa tacaaatctt ctctaaagga accttcttta
    25861 atttttttct ttaaatcttt atttgttgca gctataattc taacatctat tggtataatt
    25921 ttacttccgc ccattctcat aacttctttt tcctgtaata ctcttagcaa tctctgctgt
    25981 acatctaaag atatatcacc tatctcatct aaaaaaattg ttcctgtgtg tgctctttca
    26041 aatataccca tttttccacc ttttattgct cctgtaaaac ttccttcatc atagccaaaa
    26101 agttcacttt caataagtgt atctgacaaa gaagatagat taactgcaac aaatggcttg
    26161 ttttttctta gagattcatt atgtattgcc tgggcaaata tttcttttcc tgttccattt
    26221 tctccaagta tcaacacaga aaagtctgta gttgctattt ttcttgcaat attaattttt
    26281 tcttttatta ttttactctc acctacaaca ctctcaaatg tatactttga tacaaaacct
    26341 tttgactgaa gtttattttg aatcttgtcc tcaagcactt gaattgcact tatattttta
    26401 atgcttataa tactctttat tcgttcatta ttttcataaa catttacttt attaattatc
    26461 agttttttgt tatttaaatt tactacttca tcattaactt catcttcttg aaaaaatatt
    26521 tttttgacaa ccttatcact aaataagtcc ataaagttat tagatataat ttcattttgg
    26581 tctattccaa ctagattaga aaatactttg ttgcaatata taaattttcc taatttatca
    26641 acagaagcaa taccttcatc tataatctcc aaaaaactct tcatggtttt attcatagtt
    26701 gtataatacc tatatccact tactgtatct tcattgtatt tttccttaat aatatgtaat
    26761 ttatctatag atatatttag ttttgtaaag atttctataa ctgtatttat atcaattacc
    26821 ttatcaccta tgtcaattat ttgctttatg ttttgtggta tgctgtttct gcttcccgta
    26881 ataattccaa tctcacattt agacttatca caacctggat aatatggtat tagattaata
    26941 tgaattaatc ctagttttct aattatcttg gcagtttcat ctgctgactc tttataagca
    27001 tctataacca taacatcaga atcattttct atacttatta tctgatttat attttcaata
    27061 tttatagtac gatgtactat tacaataggt atatttttat caatattatt atgtatatat
    27121 tcctttatat cattgtctga acatactaca agctcatagc ttgacagttc aatatttatc
    27181 ctatttacat ataccaagtt atctatatta caaaattctc caaatatatt ttccaattgt
    27241 tttgatatat ctatatttat tttgtcatca gttgatacaa ataaaatatt atgttttttc
    27301 atagtcccac ctcctgttta acgagtatag aaagtaataa tttggtctat tgtagcactt
    27361 tttaaaaaag ttttaaatct taaaaatcaa attttgtacc atttactatt attttccata
    27421 ataaaataat gtaagctatc ttttttcaca tataatttaa tttctaaaac ggttagtttg
    27481 acattattgg aatataaaca aaaatttaat ataaattcgt taatatatta atacattttt
    27541 aagaatgaca aggaataaat tataacaaat tttaggaata tataataata gggtcttaga
    27601 acttagttac aagttctaaa accctatttg tttagtgtaa aaaacatcat aaaatttagc
    27661 ttaaatcttt tcacataata ttactctttt tctaagtgat aataaaatat atctattcct
    27721 ctaaaaactg taaaaattcc tgattaaata gtttaagctc atcatagaat atagcatgac
    27781 cactatactc aaaagtatat aaaattgaat cttctatttt ttcattcata aaaactgcaa
    27841 attcatacgg acatatttca tctaatttcc catgaaatat accagtaggc actcttacac
    27901 attttaaatc attaaataat tcttcatctc ttaaagatac agcagttcca atagtgccaa
    27961 tacctgatgc actaaaacca atatcattaa accatcttct aaagctttct ggtggatttg
    28021 atgcaaatac tttttcgcca aaatcggtta ccatttctgg tctatcagta catgcttgtg
    28081 ctatcaattt atttacatct tcacgtgtca taccatatgg aaattctgga ggtctttgta
    28141 caaatgatgg tgcagcagct gcagctaata ccaattttga cactccatat ccattaaata
    28201 aactcatata cctaagtacg attgctcctc ccattgaaaa accaacaagg gtaaagtctt
    28261 ttaatccaat agcatgtacc accttataaa tatcgtctgc taattggcta taagtatatc
    28321 ctcctgatgt tgcatcagat ttaccaaaac ctcttaaatc aattgaaact gttctatatc
    28381 cgagttttgg caatatattt gtttgatatt caaatatctt atgtcctaag ggccaaccat
    28441 gtataaaaag tacagttttt ttagcactcg gattcaaatc atatactgct atgtttatat
    28501 cattcacata tacataatac atatcaacag caactccctt caagaaaatg tatgatggtt
    28561 attttatata tatgaataaa atgatgaata attaaatttt caaatttatt tacaatactt
    28621 ctctattgcc ttttcaaata aacttacatg aagtttttca tctaggatta ttctatttaa
    28681 tatagctttt atataagggt cttcaataag acttatatct ttataataat tattaatagc
    28741 cacatgctcc aaatgcaaat ctagttttag tctgttacaa atagaatttc cataacatac
    28801 aaaaccacca ttccaatatg caccacaaga acttgtagaa cctctatata caggatttcc
    28861 acccaataat cttatagtct ttgctaatat ctccatatgt aacatttctg ttatagatat
    28921 atttatccac atttcactta actctctatg cgtttcatct aaatcaaaat tatggtatag
    28981 atattgattt acactcgtaa attcacttga tactccggca tagtcatcca tcaataattc
    29041 tgcatagtac ttatttggac ctaaaacttt tatctctgga tatggctcat cacttgaata
    29101 tccatttcgc ttgtgcatgt cataatgtgc atcactcata atatctcctc ctttaaattt
    29161 aatgtatgat attaattgta tgcatcacaa ctttttcata taacttagat aataaaatct
    29221 acttaaataa taaaaagcca tattaattaa aattaacatg accttttatc cacaaaatta
    29281 ctttttaatt attcatcttt tccagctact gatagctctt taataacaac tgaaggcgaa
    29341 cctatactac tcattggaaa ttctaaatct gctcctatag cttcaatatc ttttaacagg
    29401 tcaaaatagt ttcctgctac tgtaatttgc tctactggaa atactttttt tccttctttg
    29461 atataaaagc ctttggcagc taaagaaaag tctcctgtta ctgaatttgc acctgaatga
    29521 agtcctgcaa agctagtaac catcaaccct tcatctatat cctttataat ttcatctaaa
    29581 gatttatctc ctttctctat ataaaaatta gttggatata tgcttatagg tgatgaatat
    29641 gaagatttta ttccatttcc tgtagtcttt acacctgcct tattagccgt ttttaagtta
    29701 tgaagtaaag ttataagctt tccatttaaa acaacttctt ttttaaatgt agctactcct
    29761 tcatcatcaa aaggagtaga tgccatacca ttttctaaaa gtgggtcatc aactattgta
    29821 actataggag atgctatcat gtctccttct ctatttttca ataaagataa tcctttttga
    29881 gctgaatctg cattaaatat cccagaaaat gtgctaagca aagataccat agcttcatta
    29941 agcaatatag ttttatattt acctgatgga atactcttac cacctacttt agataaagca
    30001 ttatcaacac caagttttgc tatctcacaa ggttttattt cttcaataga atttgctata
    30061 ttatatccta ttccatcata tttttgtcca ttgtcttcta tgataggaac tacaaaccct
    30121 ataagcatat tagttttatt gcttaaatta agacctttag tattagatat accattactt
    30181 gatacagaat aagatatagt acatttagat aaatttacca ccttatctga ataagcttta
    30241 gtctctcttt ccatttctaa agctaaatca atcaacttat ctgcctctaa attttctagc
    30301 tctttagaat aagtctttac atcattatag tgcttatctc cttcatatat aaattgtaca
    30361 tcttcatttt caatagtgtt tactccatct tttacatttt ttatcaacat atcaacagct
    30421 ttatcatcta aaatttctgt ataagaataa cctatctttc catttacctt acctctaaaa
    30481 gataaaccaa aagatttatc aagattgtat ttctcaactt ctccttcata tatatttata
    30541 ctcaaatttt ctcctgtata ataatatatt tcacactctt caaaaccttc acttagagcc
    30601 tttttaaata atatatcttt aaaattttta agttccacaa ttatccctcc tatcttccac
    30661 ctacagtaat ttcttttacc cttatcatag gttggcctac attagttggt atacttcctg
    30721 atgatgagcc acacatcccc tgagcttgtt ttacgttatt cccaaccata tctatattca
    30781 taagtatatc gctacctttt ccaattaaac tagcacctct aactggctct tgtatttctc
    30841 cattttttat taagtaacct tctgaaactg caaaattaaa ctctcctgtt acaggattta
    30901 cagaaccacc acccattttt ttagcataaa gtccatctgg tattgacttt ataatatctt
    30961 ctggtctatc ctctccagca gcaatataag tgttagtcat ccttgaagtt ggtgcaaatt
    31021 tgtagttctg tctacgagaa cttcctgtag gattcattcc cattcgtcta ccattaagtt
    31081 tatctatcat ataagacttc aaaattccat tttcaatcag tatattcttt tgagttggat
    31141 ttccctcatc atctatattc atagaacccc agtagtttgg tattgtacca tcatctatag
    31201 ctgtaatctt tgtggaagca atctgttgac ctaatttatc tgcaaataca gagttcccct
    31261 ttgcaactga tgtagcttcc aaagaatgtc cacaagcttc atgaaatatt actccaccaa
    31321 atccattatc tattgctacc atcatattac ctgcaggaca atttttagca tgcaacatag
    31381 tatgagctac tctagctgat tcttttgcat aatattctgg gtctatttct tcaaatattt
    31441 caaacccttt acaacctcca ggaccttcaa atccagtttg attttcatta cccttagatg
    31501 caattgaact tatccctagt ctggttctta ttcttctatc ctcaacatat ataccttcag
    31561 tgtttgcaat taatattttt tggtctttat ccaaatagct aacacttact tgagatatat
    31621 cattactaaa ttcttttgca ctcttatatg caaccttcat aacacttact ttatctctat
    31681 ttcctattga atttggataa atttttatat tatgtatgtt atttatttta atactgtcat
    31741 ttaatattac actttttcca tcttccaatt tccctaaagc aacagcagct ttgtatgcta
    31801 catccaacag actatttaat gaattgtcac ttgtataagc atatatactt ttcaatcctt
    31861 taaatattct tattcctata ccataatttc ttccacctat tgcattttct actttattat
    31921 ctattaaact aatagaatta tttatagtgt cttcttcaaa aatctcagca aaatctcctc
    31981 cagtaattag acacttttct aataccttag aagctatatt ttttgaaagc ataaatttac
    32041 ctcctacttt aaatttttaa ttaactttta ttcaatcttt ttacttgtta acaaacatta
    32101 tatactatat tacttaaaat aaggtaatta tgaatatatt atacatatgt tttacactaa
    32161 aatgttatca cattttatct atacataccc atataactag ataattaaaa tgtataatat
    32221 tatttgctat agaaaataat acactcatac ataataaatt ttaggagtga agtatatgaa
    32281 tcaagaatat gtaaaaggaa atcctatttt tactaatatt aataaagttc caagacaatt
    32341 tccatacctt actgatgata ttgatactga tgttataatt gttggtggtg gcgtaactgg
    32401 atgtatttgt gcttactatc tagctaaaaa caatataaag tctgtcattc ttgaaaaagg
    32461 aaggattgca catggaagca ctagcgtgac aacttctcta ttacagtatg aattagatga
    32521 caatttgata gatttaacag aggttatgac tctaaaagat gctctaaaag catataacct
    32581 ttgtacttca gcacttgaag aattagatac atttatagag ctatatggaa ataagtgtga
    32641 ttatgccaaa agagatactc tactttatac tgccaacaaa cttgaagtta aggctatcaa
    32701 agaagaatat aacttaagaa aagaaaatgg atttgatgtt gaatatattg atgaatccac
    32761 aaaccctttt agctttgatt taaaatcagg attgatagca aagaatggag gacgagaatt
    32821 agacccatat aaatatagtc accatttgat tgatgtgagt ttaaaaaatg gtcttcaagt
    32881 atatgaaaat acagaagtaa aaaaagtaga tttatcaaat aataaggtta ctgctgaagt
    32941 atcgtatgga tacaaagttc atggtaaaaa attaattgta gctacagggt acaatacaag
    33001 tttatttaca aaaagaaatt ttgcaactaa gtcaaatacc tttaatatag caactaaacc
    33061 acttaaaaac atagcttctt ggaaaaacaa cattttaatt agagataact gtgacccata
    33121 taattatcta agaactacta aagacaatcg attaattata ggtggtgaag atgtaagttt
    33181 tgatgatata gaaaatgaaa ctttagccaa tgaaaagtac gatattttag aacaaagatt
    33241 gaaaagtatg tttaaggata taaaagacat tgaagttgaa tataaatatt gtggttgttt
    33301 tgcttcaact ttagataatt taggttttat tggtccagat aataaaaata acaatctatg
    33361 gtattgctta ggttatggag caaatggtat actctttgca atattaggag gtataatgtt
    33421 aagtgaatta tatcttggca aacaaaataa aaatatgaaa ttatttaaag tagatagatt
    33481 tgataaatag atattatata ttaaaagact gtaaaaagat gaaactttat aattctaaaa
    33541 gttaactttg atacagtctt ttataatgtt ccttttaaaa atactttatt tataattaaa
    33601 tataaagtaa aatgttaaaa tataactaat aaaatttagt cataagataa tatttaagtt
    33661 tatttgatga aatatggagg aattattatg aaggaaatac tcgttattgc tcccactaaa
    33721 ggaacctatg aaaaatcaat tcacatagtt aaaaaaaaca aatatacaaa tattgatgtt
    33781 gtatttggca atctaaaaga aggtatacct cttgctgaaa aaagtattaa tcatggtact
    33841 agaattatca taagccgagg tggaacttac aatatgttaa aagctactta caatatacct
    33901 atagttgaaa ttaaggtaga tgcttatgat attataaaaa gctacaaaga ggtaaaaaat
    33961 tccaacgaac catttggaat aattggattt aataatgtca tctacggttt cgatattata
    34021 gaagaaatat tgaataagaa aataactatg attgaaattg aaaaagaaga agaaatttat
    34081 gatgctatag aaaagtacag aaagaaaggt ataaacacat atataggaga taccactgtt
    34141 gcacatattg ttaagagact taattgtaag ggaatattaa tcgaatctag agaagaaaac
    34201 atacttagag ccattcaaca agcagagcaa atactcgaag caaccaagga tgaacaaaaa
    34261 agaagattac agatagaagc tatgacagat tttgtacatg atggaataat aacagttgat
    34321 aaaaatttta aaataacatt atttaataag agtgctgaaa aaatatttgg tataaaaaaa
    34381 gaaaatgcac tttatcataa tgttgtagat gttatcccaa acacagttct tccacaagta
    34441 gttgagacta tggaacctca aattggtgaa atacaaaata tagggagtac aaaaattatt
    34501 acaaatagag ttccaataat tgttgatggc cagattcaag gggctgtttc aacatttcaa
    34561 gatagcaagg agataagttc ttttgaacat acaataagaa ggagcttatt aagcaaaggt
    34621 ctatctgcta aatacacttt tgatgatata attcatgcta gtgaaaagac aaaagattgt
    34681 atagaacttg caaaaaaata tgcttgttat gatactccta tgattattac tggagaatct
    34741 ggagttggta aagaactatt ttgtcaaagt atacataact atagtaagcg taaaaatgca
    34801 ccttttgttg ctgtaaattg tgctgccata cctccatctc taatagagag tgagtttttt
    34861 ggttatgagg aaggttcatt tacaggtgct agaaaaaaag gtaaagcagg tatattcgaa
    34921 ctagcacatg aaggtacaat cttcctagat gaaataagtg aaatccctct tgaacttcaa
    34981 ggtcgattat tgagggtatt gcaggaaaaa caagttatga gaattggtgg tgataaagtt
    35041 attcctatag atgtaaaaat tatctgtgct tcaaataaag acttaaaaaa tatgatgcgc
    35101 aatgctttat ttagacaaga cctttatttt agaataaata tactaacatt atatcttcct
    35161 tcattaaaag aaagaaaaga agatattata aaattatcag aattttttat acataaatat
    35221 tcaagcaaat acaataaaac gcctttaatt atcactccaa atattaaaaa ggcacttctt
    35281 gaacgagaat atgaaggtaa tataagggaa ttggaaggta tgatggaaag ggctgttatt
    35341 gtggaatcat ttgactcgat tttattagaa aaggttagca atgaatatac aaataatata
    35401 gttgataaag ataatagtga ttttgaatgc agtaatttag atttaaaaac tttagaaaaa
    35461 aaatatatct ataaaattta taacgaaaat aatagaaata ctacaaaaac ctgtgaaatt
    35521 ctaaagataa ctcgctctac tctatggcgt aagttaaaag aaatagaaga tgatgtttaa
    35581 aaataataca tacctatata tatcaaaacg ttttatgttt aattttaata cataagacgt
    35641 ttatttgttt tcaataaaaa atacaattat atgataaaaa gaatctttgt aagtgaaatt
    35701 ctcgtcaatc atacttttaa ttataagtaa tctacagcat ttcaatcgat tattaaaaat
    35761 aatcatgata actaaagata caaactctat atattggcat agtaattgct tttataatac
    35821 ctatataaaa atgaaaggga gtgatactag atgcacatct taaaatcagt gaaaaagata
    35881 ccaggaggac ttatggtctg tcccttgtta ttgggagcac tatttaatac agtatgtcca
    35941 caagctcttg aaattggagg attcacaaca tccttattta aaactggtgc aatgagtata
    36001 cttgctctat tttgtctatg caatggagct caaatcaata tcagacaagc tggtaaacca
    36061 ttgactaaag gtatagtact tacagcaaca aaatttataa ttggtgcagt attaggtatt
    36121 attgttagta aatttattgg acctaaaggt ataattggta ttacacctct tgccatagtt
    36181 gctaccatga ctaattcaaa tggaggtcta tttgctgctc ttgcaggtga atatggagac
    36241 tccacagatg ttggagcaat atctatctta tctctaaatg atggtccttt ttttacaatg
    36301 cttgcttttg gagtaactgg acttgcaaat gtacctatag tagcactatt tgcagcactt
    36361 ataccaatac tacttggatt tatacttggt aaccttgatg aagatatacg agaatttctt
    36421 gcacctggta caacattatt aattcctttc ttcgctttcc ctttaggagc agcattaaac
    36481 tttaatcaaa ttataactgc tggactacct ggagttgtac ttggtttagg agttactata
    36541 ataacaggta tgggtgggta ctttgtaatg aaacttatac gtgcagaaca tccagcagta
    36601 ggtgcagcta caggtacaac agccggaaat gcagctggta ctcctgaagc tttagcagct
    36661 atagacccta ctctagctac aatagcagct gtttcaacag tacaggttgc tgctgctatt
    36721 attgttacag caatatgttg tccaatgtta gtttcctatc tagataaaag agaaaaaaag
    36781 aaaaaatcta tttttaaaac aaataaaaat attgaagtaa attaatactt aaggaggtaa
    36841 aattaatgaa tgcaattatt catgcaaatg aaaaagataa tctagttaca tgtgtcagac
    36901 ctttagttaa aggtgaaaaa gtttcaattg atggaaagtc ttacatagta aatgataata
    36961 tacctgtctt tcataagatg gctacagaag atgtaaaaaa aggtgatgtt gtatacaaat
    37021 acggtgaaat cataggaatt gcaacagttg acataaaaac tggtgactat gttcatgtac
    37081 ataacattga aagtacacgt ggtcgtggag ataaaaaata ggaggaagtt aaaatgaaat
    37141 taatgggtta tttaagagaa aatggtcagt ttggtattcg taatcatgtt ttaattattc
    37201 caacatctgt atgttcaagt gagacagcta caagaatagc atcacttgtg cctggagcaa
    37261 tagcaatccc tcatcaacat ggatgttgtc aaattggttc tgatatagag cttacagcaa
    37321 agacattaat aggatttgga aaaaatccta atgttgccgc agttttagta gttggtcttg
    37381 gatgtgatgg tattcaagca aaagaattag catctgaaat agctacaaca ggaaaaaagg
    37441 tagattacgt tgttatacaa gaatgtggtg gaacattaaa aacagtttct aagggagctg
    37501 aaatagtaag taaaatggct cgtgaagtat caaaagaagt aagagttgaa tttggtatga
    37561 gtgaaattac attagcactt gaatgtggtg gttctgaccc aacaagtgga atagcttcaa
    37621 acccttcaat aggcgttgca tcaaaccttc ttgtagatga aggtggaagt agcatactaa
    37681 gtgaaactac agaagtaatt ggtgcagaac atttgttggc tacccgtttt gaagatgaag
    37741 aaatgaaaga taagtttctt aaatttgtaa gtgatgtaga aaaaagagca attgctatgg
    37801 gagaagattt acgtagtggt caacctactc caggcaataa aactggtgga ctttcaacaa
    37861 ttgaagaaaa gtcacttggg tgtatgtata aggcaggcaa taagccattc aaaggtgctc
    37921 ttgaatatgc tgatattgta cctcctgata aaaaaggatt atattttatg gatactccag
    37981 gtcaagatat agattctatc actggtatgg tagcaggtgg tgcacaaatt gtaatctttt
    38041 caactggtag aggtactcca acaggaagcc ctatttcacc agttattaaa atcactggga
    38101 atagtgatac atacaacaaa atgccagaca atatcgatat aaatgcaggt agaattataa
    38161 cagatggtgc taaaatagca gatataggtc aagaaatatt taatgaaata atagaagtct
    38221 gtaatggtaa acataccaaa gctgaaagtc ttggtcatag agaatttggc atttacagaa
    38281 tttcatctac attttagatt gtaacaaaat atcttttata aatataatac ttatgtagat
    38341 acataagcta aaagttcttt ctaatactat aaaaattttc tatactgaaa aggaactgta
    38401 tcaaaattat tttgaaaaca gttctttttt taacctcttt tactcaaaat attataaaat
    38461 aagatttaaa caataaacgt atcttgatta atctctaaga agacataaat aaagctaaat
    38521 gtaaagtggg ataaataaaa tttaatatct ttgtatgaaa agatatttgg tataatatgt
    38581 ctgagagaat tcttatttgt aaacaaataa aggatggagg atgaaacaaa agaatgaact
    38641 ttgaaaacac aaaaaataaa aaaataatag ctactttact attgacactc cttttaatcg
    38701 tgtcattaac atgtgtcact tttattatga atctaaataa agtaacacat aatgaaacag
    38761 aacgatatct tgtagaagtt tcacaaggta tttccactac aattaatgtg aaatgtaaaa
    38821 gtatatttag gacactatat tctatgggag atacttattt tgagattaat gatagtgaaa
    38881 aagaagtcaa tagatactta tcaaaaaaat taaaattatt tgaatttgat tggttaggta
    38941 ttatagattc taatggaaat tttgtaagtg cccttaaaga tacaggtaat gttaaaggac
    39001 aagactttta tagaaaagcc cttcaaggca aagaaacaat tactcctgtt aaatcacaat
    39061 ctggtacata tggaatttta tattctgtac cactatacaa tggcgataaa attgttggag
    39121 ctgttgctgc ttggaatact attgatacta tgagaaattt attaagtgta gaaagctttc
    39181 atggtgaagg attttcccaa attatcgacc aagatggaaa ttttattgta agttcagcaa
    39241 acaaaaatgc tccaaaaaat gtggtaaatt tttttgacat gattaaacac caaggaaaac
    39301 aggttgataa aaataaactt gaagaaatga aaataaactt aaaaaagaac aaaactggtt
    39361 ctatgtatta tacattaaat gatggtattt ctaaggcaat gcattatctt ccattacaag
    39421 aagaaaactt atacctcctt tcagttgttc caacaaaaac agcaagtgca cagtttgatt
    39481 tacttctaaa aaaagcaatc ttcatcaata ttttaattgt tatactattt ttattgctta
    39541 ttatattgat tatgtttata aatcaaaaga acagggcaca acttataaaa atcgcctatg
    39601 tagactctgt aactaaaggt tacagtaaag cacgttttga tattgaagct aaaaaaatta
    39661 tacagtcatc ttcatcagaa agctattcat tggtatctat aaatattcag aaattcaaac
    39721 ttattaatga ttcttttggt agtgaagcag gagataaaac attaaagtac atacatgatg
    39781 tcattagtaa ttatctagaa ccaggagaat tgctttgtcg agtttctaat gaccagttta
    39841 atgtacttat taaaactatt cctcaaaaag aaattcttaa gtacatagaa aatatcacca
    39901 atgatattaa tagtttcaat aaaaatgaag aatgtaaata ttttatagct ctatctatag
    39961 gtgtatataa aattgatgac ccaaatctac ctttagtttc aattcaagac cgtgcaaatg
    40021 ttgcacgaaa aaataataaa ggaaacattg gaaatcatcc actttataca tgtgtttttt
    40081 atagtgattt agagcgttta aaaatgatta aagaaaaaga aatggaaaat agaatggagg
    40141 aagcattaaa taataacgaa tttatagtat atcttcagcc taaaatcagc ctcaaagata
    40201 atactattgt aggtgcagaa gcattagtaa gatggcaaga cccaaataaa ggtcttatac
    40261 caccagacga atttattcct ttctttgaaa aaaatggttt tattacaaaa ctcgaccact
    40321 atgtttttga aaaagtgtgt agtatgctaa gaaaatggat agataatgga gaaaccccaa
    40381 tacccgtttc agttaatttt tcacgtgcta atttaaataa catagacttt ttagaaaaat
    40441 acagaacgct ttgtaataaa tacaatattc ctactaaact tttagaaatt gaattaacgg
    40501 aaacacttgt atttgaaaat ctccaaaaac taattaacat aatagaccaa atccacgaag
    40561 aaggttttca atgttcacta gatgactttg gaagtggata ctcttcactc aatatgttaa
    40621 aagaaataaa agttgataca ttaaaacttg accgcgcttt ttttagctca cctaatgcag
    40681 ataatattgc tgaaaatcat gtaatagaat ctatagttaa tttggcaaaa aaattaaata
    40741 tgaatagtat atcagaaggt gttgaaacaa tcttgcaaat ggattatctt aaaaaaatta
    40801 attgtgatat gatacaggga tatgtttttt caaaacctct gcctcaagaa atatttgaga
    40861 aaatgacttt tggaaaaaca ctagaagaaa ccaatatgga tagtttcagt taaataagat
    40921 aaaaaacttg tctctataaa ataattttaa tcattttata aagacaagtc tttttatttt
    40981 ccaatttaat tttattttct aaatttctta tactcggctt gttttaaatt ccctttttaa
    41041 gaataataat acgattatca tagcaataaa atctgcaact ggctgtgcca accaaacacc
    41101 atctaaatta aattgaattg gaagcacaat gattaatggt ataaataaaa taaattgtct
    41161 taaaagagtt aaaaacattg aatgtttaac tttacttata cactgaaaat acacaggccc
    41221 tacaatagaa atccccatta taggcaatgt aattagattt atgtttatac ctcttactgc
    41281 tatatccatc aaatctgaat ctttattaaa tatacctaca aatacttctg ggaaaacttg
    41341 tactactaaa aatccaaatg acaatatgac aactgacact atgatagata atattaaagt
    41401 tttctttgca cgctcatatt gttttgcacc ataattgtat gatattatag tttgcatacc
    41461 ttgattcaat ccaaacacag gcatcataaa catcaataaa atagatgtaa gtgctgtcat
    41521 agctccaata gctaaatctc caccataaac ctttaaagaa ttgtttgtaa acatgtgagt
    41581 tatacttata gctacttcca tagcaaaagg tgtcattcct attgcaaata ccttctttac
    41641 tatatcttta ttcaatttta agttacattt ttttagtttt aaattggact tccctcttat
    41701 aaaataatgt attacccaaa agaatactac tatttgacag agtactgttg ctatagctgc
    41761 tccttttata cctaaattaa atacaaatat aaatataggg tccaatatca ggtttaatat
    41821 acatcctaca atcattgtcc ttgctgctaa ttttggatta ccttctgccc taattgcatt
    41881 attaagagaa aatgcaacta aattaaatat acttccaacc aatatgacac tcatatagtc
    41941 ttttgcataa aatattgaat ctttacttgc acccaaaata aaaagtatat cttctaagaa
    42001 aactaatcct aatatagtta taattaaaga gataattata gataatgtca aagcattacc
    42061 taatatattc tctgcttctt ctctatttct ttcccctaac tttatagaca atcttgtgct
    42121 agcacctact gataccaaca ttccaaaagc tattattaga gtaaatactg gcatagttac
    42181 accaagacct gcaatagcta tagagccaat accttccata gaaccaataa aagctctatc
    42241 tactacatta taaagtgaag ttaccatcat tgctattatt gcaggtatcg aatacctaaa
    42301 taataaaatc catatttttt catgtcttaa tgcttcttga ttctccatgt tgtcaccatt
    42361 tacaccatgt cataagttat acaaattggt ttatttgttc ttgggtccgt tgctatttct
    42421 gcatcaatat taaataattc ttttagatta tccttcgtca taacatcata tgcatcacct
    42481 tcacaaacta ttttaccttt cttaatacct atcatgtggt cagcaaatct tgctgcatta
    42541 ttaagttcat gtattaccat gacaatagtt cttccttgtt ttttatttag ttcatctaat
    42601 aattttagta tctctaattg atgtgccaaa tctaaatatg ttgtaggctc atccagtaat
    42661 aatatatcag tttcttgtgc caaagccata gctatccatg ccctttgtct ttgtcctcct
    42721 gataaatctt ccatatttct atccttaaat tctgcaattc cagtaacttc taaactccaa
    42781 tttacaatct ctctgtcttc tttactagaa ttaccaaatc cacttttatg aggaaatctt
    42841 ccataagaaa ttaattctga aacggtaaga ccactaggag cttgagggct ttgtggaagt
    42901 acagccatat cttttgctat ttctttagac ttctttttgt agatgtcctc tccatttata
    42961 tatattttcc cactattagg gctaataatt ctacctatag ttttaagtat tgtcgatttt
    43021 ccacaaccat tagcccctat tatggtagtt atttttcctt ttggtatatt taaatttaaa
    43081 ttttttataa tatctgtgtt tccatatgat acatttagat tcttagtatt tatacagttc
    43141 ataacaacac cctttcctaa tcatttacca acattaaata aataaagtac ggcactccta
    43201 ttatagaaac tactatacct actggtattt ctataggtgc tagaagattt cttgatatag
    43261 tatctgctat taaaagtaat aatgttccta tcaatgctga tactggtatt aatcttttat
    43321 gctttggtcc tattattttt ctacctatat gtggagctat taaacctaaa aatgaaatac
    43381 tacctgctac tgctgtcgat acaccagata aaattactgc atatattata agtcttcttc
    43441 tttgtttttc tacatctaca ccaagactta tagatacttc atcacccaaa tttaaaacat
    43501 ctatatattt agatttataa atagttatac ccataaaaat cactataaat ggaagcacag
    43561 ctattacata tttccaactg gttccccaaa tgcttcctga tgtccatgcc ataaccctat
    43621 taaattcttg tgttgtaaat ttcaattgga atatcgtcaa aattgaagta aaagctatgt
    43681 ttacacctat accaataagt agtaatcttg acgaatttat accacctttc catgcaagag
    43741 aatatataag aaatgctcca aataaagctc ctataagtgc aacaataggc attgtaaata
    43801 cagtcaagtt actcatacct tcatatacat taccattcat aaggtatata taaactacta
    43861 caaacaatgc agcacctgaa tttattccca aaattccaga atcagctaaa tcattttttg
    43921 taactccttg aagtattaca cctgctgttg ataatgcaga accaaccaaa agtgctatta
    43981 ctattcttgg taatcttaat ttaaatattg caatttcatg attacgctga ccctgcccta
    44041 aaaaagtctt tataacatcc attggttcta tagaaaatga gcccatattt aaactcaata
    44101 aaaaagtgat aaaaataagc accattaaaa ttgatataac aagtaatgtt ttagaattta
    44161 tttttataat atttttcata gtacctattt ctcccccttt ctaacaaggt atataaatat
    44221 tggcactcct ataagtgctg ttatagaacc tactggtgtc tcatatggag gatttatcat
    44281 cctacttaat atatctgtat atacaagcaa tacagctcct aatactaaag agctcggtat
    44341 tatatactta taatctgaac ctactattcc tttagctatt tgaggaacta taagacctat
    44401 aaaaataata ttaccagaca ctgacacaga tgctccagtc attaatatta caagtactat
    44461 acatataaat ctaacaaagt tagttttttg tcctaatcct attgccactt cttctccaag
    44521 acttaatata gttattcttg gagccataat aatagctaaa ataaatccaa taccaccagc
    44581 tacaaatagc aattttatac cttcccactt cactcctaca agccctcctg atatccagaa
    44641 acttaattgt tgagataggt taaaatacat agatattgct gatgccaaag aaattagcaa
    44701 tgtaccaaga gcgactcctg caagagctaa ttttacatta ttaactcttc ctcttgattt
    44761 agaacttata aaatatataa ataatccact tatacttgct ccaataaatg caaacatcat
    44821 tacactaaaa cttccatgta taagttgagg aagttttttt tgaagtacca gtgatatcga
    44881 aattgcgaat gtagctcctt gtgtaattcc tataacagat ggttcagcta taggatttct
    44941 cgttattcct tgcattattg ccccagaaac tgctaaaaac cctccaacaa gtgcagctgc
    45001 tattgccctt ggaagtctaa catcctttac tattctcata tttattccat cttccatttt
    45061 tatcaaacta tctataacag ttgatagatt catatctttt gccccaatag ttatggataa
    45121 tacaattcca aatacaagta caactatact tactaatatc aacaaataag ttatattttt
    45181 tttactcagc ttagtcaatt atcctacctc cttttccctt ttaatcgtca gtataatatc
    45241 atctattaag tattttaatt ttaagattta ttaaaaatag gtgtgaaaaa tgaatatcat
    45301 tatctcacac ctactaagtt aagaattact ttgttaattc atttttaact gattctaata
    45361 ataactcttt tccaattgga ttgtatgatt gactgaaaaa tggagcagca tcaagtattg
    45421 ttacattacc atcttttact gctcttattt gagcccagat agcactattt tctaaatctt
    45481 ttttatctgc ttctgtagca attacaacta tatggtctgc atctatatct gttaaacctt
    45541 ccatacttac cattggtagt gttattccat cctgttttgg catattctta ggtctagcta
    45601 atttcatatc atcattgatt agagtaccta ttccaccatc actaaatacc ataaattgac
    45661 ctgaacttgc caacactggt aaataagttt tttctccatt cttttctata acttccttac
    45721 ctaactttgt agctttttca tcatacttct gtagccaact tttagcttct tcttctttgt
    45781 caaataactt tgaaacatca gttaacttgc ttctccagtc atttgcataa tctttcatca
    45841 taactacagg agctatttct tttaattggt catatatttt ttcttgtctt tgactcatta
    45901 ttattaaatc aggatttact tctaatatag cttccatatc catagtatcc atcattgagt
    45961 gcccaactat ctttacacct ttaagctctt ctcttatgta acttggtaat ttatcagttt
    46021 catatgagtc tacatttgct gttgcaacag gcttataacc tgctaataat agttcttcac
    46081 tacttcctga tatatcaact atttttttag gatttgatgg tatcttaacc tctcctttaa
    46141 cagattgtac aactcttgtc tctgatttat ctttatcctc tgtattctta tctgaacatg
    46201 ctgtaacaag tactaatgta gttataatag atataaatat tgcaagtgat tttatttttt
    46261 tcatgattac ttctcctact tgtttattat acttatatga tattgattat cataagcaca
    46321 tatttattat agcatttttc tatttttagt caatattatt ttgtaaaagg ataaaaattc
    46381 ctaattaatc ttaattatat atagcttaga taaggttttc ttatattaaa cagtattttt
    46441 ttaaagaatt ggacacaaat acaatgactt ttcagttaaa caatgataaa atgcaattta
    46501 tagataatga atttagtagg gaggattcaa aacatggtac atttagtata ttgtgataat
    46561 gcaggaaaaa aaggagaaaa ggtcttagat aaaatcttat caggaacaaa aacaatggtt
    46621 attagaggtg ctgctggtag aaaaatacca catagtagag tatttgaaaa tgagttactt
    46681 tattttatgg aaaaaggaac tggaaaaata tctgcaaaag ccactgttaa aaaggtagaa
    46741 aactatgtta aattaacaga agatgaaatt tctaaaattt taaatgaaaa tcaaccaaaa
    46801 ttaaatttat ctgaaaagca aaaagttcgt tggcataaaa aatgtttatg cttagttgaa
    46861 tttgaaaatg ttgaagaaat aacatctctt gattttgacc atcaaggaaa tatggatgat
    46921 tggcttattg ttgaaaaaat tgaagatgta gttgttggta ctagtatacc ttacaattat
    46981 gagaagtcta aattttaaag tatcaataac ataatactat attgctaaac tctacttaaa
    47041 taaaaaaaga gtgcatttaa taattataaa aattattttt atacactctt ttttaataat
    47101 aattttaaat tacttacttt ctaatctttc atatacatct ataaattctt ctgctaattg
    47161 ttgaaaattc atagctgtca ttaaatggtc ttgtgcatga ataagtataa cacttatttc
    47221 agttttatta ccattagctt cattttgtat caattctgtt tggaatttat gagctttatg
    47281 aattgattct ttcgactttt caatacattc tctagcttta tctatattcc cgctctttgc
    47341 ttcttttatt gcttcaaatg ctagcccttt cgcatcacct gcaaatccaa ttattccaaa
    47401 agatatctct atcatcttct catccattta ttcgacctcc taaatatctc tatagcttga
    47461 tatgactaat ccattctttt ctaaaaattc tttgactttt ttagatgtaa gtatcttgtg
    47521 ctctttcgtt ctatcaatag cataagatgt agaatttaaa atataatcat ctaaaaaagc
    47581 tgggtgagac ataatatcca ctacatcata cttcattatt tcgtctatat tttttataaa
    47641 atattcttca cttacatttt ccttataaaa actatctatt aaaggaacta ctttagaata
    47701 ctctaaatta tattcaaatc cacctcttat cggaagatta tacttggtta caatcttctc
    47761 tattactgac tttaaactta ctaaagtatg gatatgatgg tgactatcta aatgagatat
    47821 atctattcca agccctttta ccctatctat ttgagcacaa agttctctat aaatctcatc
    47881 acaatccatt ttttcaataa tttcgtctgt aatcctccta ataaaaaaac cgtctttatc
    47941 aacaatagtt tttaagttag ataataatgg tctaccacaa cttaaagtca tatgaactcc
    48001 acaatttaaa gttttatttt ctttaagtaa gcctactcca tgttctaccc caggcatatt
    48061 tgccatcata gaagtagacc taactatacc attattatga gctgaaatta ttccatagtt
    48121 cacagcttca caatatccaa aatcatctgc atttattata attttagtca taccataacc
    48181 tactttctat agacaactat ctattaaatc taggaagata atctttatga gcttccaaca
    48241 tttcgtctaa tatagttttt gctaagtcat cagatggaat caatgggttt atacaaagtg
    48301 ccaaaagagc agattcataa tcgccatata cagctgcttt agctgccaat acttcaaatg
    48361 atttgatttg acttactaat ccatgcacag aatctggtaa atatcctata cttattggtt
    48421 ttgggccatt ttttgttatt acactactta cttctaccgc ttgttcatct ttaaaatctc
    48481 ttatagaacc cttatttaat gtattaacta cttggatatc ttttttgtca ttgtatatag
    48541 aacttattaa attacaagca gcatcactat agtaagcccc tcctcttttt tcaagttgag
    48601 gtggttttac atctaatttt tcatccttat ataattcaaa taattgttct tccaattctt
    48661 taactacttg acctctagct tttccctctt taaactctct caactcatcc tcaagcattt
    48721 ctttagtttt atagtagtat ctatgatatg gacaaggtat tgcacccaaa gattttacaa
    48781 attcagcatt aaaatcaatt gcctttatat tttgcatact tatatctgct ttgacaaatt
    48841 tatcaattgc ttcttttgta acatcttctc catctaaaga tacatttaga ccataaacca
    48901 tatgattaag acctgcaaaa tccatactta ttctgtcact ttctacatta aatagtttgg
    48961 caacatcatt ttttaaatga attggcacgt tgcatagacc tatatatctt ctaaaattag
    49021 tatatttgaa tacagcctct gttattattc ctgttggatt tgtaaaattc accatccatg
    49081 catttggaca taattcttcc acatctttta ttatatcaaa tataactggt attgtgcgaa
    49141 gggctttaaa taaacctcca gcaccattag tttcctgccc cataactcca tgagataaag
    49201 gaatagtttc atcttttatt ctcgcatcta aaagacctac tctaagttgt gttgtcacaa
    49261 agtctgcatc tcttagagct tctcttctat ctaaagtaag atttattttc atatctactc
    49321 cagctttttt taccatcctc ttagctagat ttccaactat ctctaatttt tcttttccag
    49381 cttctatatc tacaagccat aattccttta caggtaactc ttcatatcta tttataaaac
    49441 cctctacaag ctcaggagta taacttgaac ctcctccaat tgtaactatt tttagtccct
    49501 ttttcatctc attataccat ccttacctat aatttaatat actctacaaa accctataca
    49561 tttatttacc aaaataaaac tacctagttg ttaattttca atttattagc ttccattttt
    49621 tcagacgcta tgacaaatgg aatatatatt aatattgata atattaaatt aaatagtgct
    49681 aaagctccac cagtccagtc acctgtagcc attgctccac ctaatatagg aggtgttacc
    49741 caaggtattt taggtaaaat tactggtgct actaatccaa aatctattgc taagtatgat
    49801 acagcactac atattactgg tgcaagtaca aatggaatca taaatatagg atttaaaact
    49861 attggaagtc caaatatcaa tggttctcct atgttaaata ttgcaggtgg accacctaat
    49921 actatcatct ctttacgtct tcttccagct attaataaag ctactattaa tcccaatacc
    49981 attccagaac cacctaaata tacaaatgca tcaaagaatg cacctgcaag tacatggtat
    50041 ccttccgttg ctcctgcttg agccaaggca gcattttctc cacctaattt cataagtata
    50101 gtttctgtaa aaggaagtgc tatatttgca ccatgaagtc caacagtcca aagtatatga
    50161 attataaatg caataagcat tgtagaacct aaactatcag ctacatttga tagtggtgct
    50221 cctaaataag tatttaaaat atctgttaag aaacttccat tggaaagcat ttttataaat
    50281 attcctatta cagtaaatat cattatagtt aacattcctg gtattaactt tgcaaatgat
    50341 cttgaaactg ctggtggaac tccatctggc atttttatag ttaatttctt taccttagat
    50401 aatcttacaa atatctcagt tgataataat cctattaata tagaagagaa taaagctgct
    50461 gtacctaagt aggtttgttg tatcattccc catccttcaa ctactgtagt tcctccctca
    50521 ggaactattt taccaatttg tggagccatt ataaaaaaga tagataaagc tataagccca
    50581 gattgtaacc catcactctc ataagatttt gctagaaaat aagcaacacc tattactaag
    50641 aatactgcca ttgtacctat tgctccccac caaaggtcgc ctccaaatgt ggtccagttt
    50701 tctccaaata tacttgccat caaatttttg tatgcttcca atggtaagtt atttatcaat
    50761 gttcccaatg cacctaccat agttataggt atcattacta taaatgcatc tcttactgct
    50821 actaagtgcc tttgagctcc tattttagca gctacaggca ctatatattt atccataaat
    50881 gacatgaatt tttccatttt acaccctcca gtacaacttt attttgaact atttaactct
    50941 acagctctat ctaacacagc ttttccatta catcttccat aatccatcat atttataact
    51001 tctactggaa tattatatgg ttttgccatt tcagttgctt ttcctaatac atatctaact
    51061 tgaggcccta aaagtaagac atcacaattt tctatttcat tttttaagtt cacttctgat
    51121 atagcccata tttttgcttc tataccgttt tcctttgctg catcctccat ttttgtaact
    51181 aataaactag ttgacattcc tgctgaacaa gctaacatta tttttatcat tttttcccct
    51241 ccaaattaga ttcattaaat attttttaag tcataagttt ttaaactata catttaaaat
    51301 atgcttttct attaattttt tcttaatgta tatatcttat ttttaaatgt atatacattt
    51361 aattcttgat attattatat accaaatgta tatacatttc aagaaaactt tttcatttta
    51421 tttaaatttt attcgacaac agcattcaaa gttaatgtat atccatagtg atatgtgtgt
    51481 gagtactcaa aaatctcact attttgtaac ttacaaattt ggcttatata taaaagtggc
    51541 tctggttctt ctaattttag attatccata cactcttcat tcgatattac agcttgtact
    51601 tctctctctg acatggctat cttgtatcca cacacttctt caacaaaatt ataaagagaa
    51661 ttttcacaat gagtcttatt taaatttgga aataacttaa ctggcatata agtaatcata
    51721 tatgaaactc ttgcatcatt agctaatctt actcttttta tttcccaaac attttcttct
    51781 aaacttatat tcaacttact tgataaattt tcatctgcct gaactatttc aagagatacc
    51841 aatatattag atactttata gcctttactt tccatctctt tagtaaatcc acttacagac
    51901 gatatattat catatatatt atttgcaata actatactac ctacacctct ttgtctagtt
    51961 atatagcctt ctttaactag attattaagt gcagacctta cagtcattct cgttacatta
    52021 aattcttcac tcagctgttt ttcagaaggg attaaatccc cttctttcaa actgtctgaa
    52081 tttattaact ctctaacatg attttctata actttataaa ttggctcttt catttaattc
    52141 actccttatt aaatctttta tataataaga taattttata tacaaacaaa gaaaatgtct
    52201 atacatttaa gataatttaa attttattca gaaatcttgt acaactttcc gagttttaat
    52261 aaagatataa atagacttat cattaatgta ccttttaata tacttgataa ggttatactc
    52321 caccatacac catttagacc caacatttct ggtctagata taaagtaagc caatggtact
    52381 cttgcaccag tcagtatagt aattataata gaaggtatat aggttctccc taatcctttg
    52441 aaagctcctg ttgttattat ttctaaacac ataaaaaatt gagaatagcc taatatttta
    52501 agataaattg ctcctttttc tattgcctca ctttcatcta taaaaataga aaatatactc
    52561 tctcctgcaa atactaatac taaagtagtt attatcccaa gtacagaaga tacagttata
    52621 gctattttgc aacctttatt tattctagaa tacttcttgg caccataatt ttgtccaaca
    52681 aaactgccta atgcaactga tagtccttca gccgtcatcc aggaaattgc ctctatttgc
    52741 gagcctactt tttgtactgc aacagctaca ggtccccatg atgctactat tactcctaat
    52801 agcattgaga atactgtaaa cataccactt tgtattgcta taggtaatcc caatttatac
    52861 agaactttat aatatttagt ctctatttct ttaaatagtt ttaatttaaa atattcttct
    52921 ttacttttaa ctattatata tataaaacat gtagtaacta ctatctgagc aaatacagtt
    52981 gcaatagcag ctcctgcaac accaagtttt ggagcaaatc cccatccaaa aattaatata
    53041 gggtcaagta taatattagt tattaatcct actgtattaa tacgaaaagg agttttacta
    53101 tttccaagac cattgaaaat tgcagtaaat actggattaa taaaataaaa taccatacct
    53161 agagctacta ttatcaaata ctgtctagac atggttataa cctctaagtc tcctaatcta
    53221 aaaaaaccta tcaattgttt attaagtact attaaagaaa ttgtatatat tattgctagt
    53281 ataatattta tttctattgc tgacttcata tatgatttag tagtgcttat attatttgca
    53341 ccaatacttt gtgctacttt tatctctcca cctacttttg aaatcataat aaatgccatt
    53401 gcaagccatg ggaaaaaacc agctgttcca actgcagtta ctgctttact tccggcttta
    53461 ccaacccata tcatatctat catgttatac cccatttgta taaatgaagt ccccattatt
    53521 ggaagtgata gcttaagtaa tttttctgta attcttcctt ctgttaaatt cagtctgtct
    53581 ttcattttcc acctctttta tattaaattt atttgcttat ataactagat taatcatttt
    53641 atttgattga gttcacaatc cttcaattta tattatcata tctcaggatt gcatctcaac
    53701 catacttatg tttaagatac agtattttac ctatctatga taaaattaat acttatgaat
    53761 ataaatctag ccatttcatc aatacatatt ctaaccctta acttaacttc aattaagtat
    53821 acatatcgta accaattaga atattttata cggtatcttc cattaataaa caaccaatat
    53881 caatgattta tatataattt tatttataca taaaatagta tactataata ataaaaaaac
    53941 tatatttgaa tactttaagc atgtttacta attgtaattt ccacacaaac ttgataatat
    54001 atgaatatat tatggtgaaa tttatagata tatattaatt atggggagat tgtgggaggt
    54061 tcttttcaca agacatttaa gctatgaaaa taaataaaaa attcaataga gttgatatgc
    54121 aggtttcaat acttactgca attattgtaa taatatcttc ctcatgtgta tattttttta
    54181 attatacact aacttataag agcatgatat actctttaag tgagaggtca aaacatatct
    54241 atgaatatgt agaaagaaat attgataaaa atacctttac tgaaattaat tctaaagaag
    54301 accaatcaaa aaagtcttat aaaagttcta aaatcctttt agaatctgta aaaaatacta
    54361 ctggagtcat gtatctatat actgctaaaa aaacaaaaga tggatcacta gtatatgttg
    54421 ttgatggttt aaattcatct aggagtgatt ttagaaatgc tggtgatttg atagaaaaag
    54481 agatttgggt agaccttaac aaagcattag ataatcatat attgttacct aaaaagatta
    54541 aatcaacatc ttggggatac atatttatat cgtattttcc tattcacaat gatgttggta
    54601 aggttgttgg agtaatagga attgaatttg aagcaaaaca tcaatacaat acatttaaat
    54661 ttataagtat agttacacca ataatagcat tattaacttg tctaatatca gcattgattg
    54721 cagtgattct atttaaaaga atatctaatc ctacatatac tgattttgct aatacagatt
    54781 atttaacagg cctaaaaaat agaaatgctt ttgaaataga tatgaataac ttaaacaatt
    54841 caaatctaaa gaatctaata tctatcatat caatagattt agacggttta aaaaagatta
    54901 atgataaatt tggccatcag acaggagact tatatattaa gcaagcaagt aaaattatac
    54961 aatatgtaat aaataaaaaa tatatagttt atcgtattgg aggtgatgaa tacataatta
    55021 ttctaaaaaa tttatctcac aaagaaataa ataatattat aaataatatt aatttaaaaa
    55081 tagttgaaga aaactcaact aatgaattaa aattatcaat gtctattgga tatgctattt
    55141 ttgatgaaaa agtagatgtt tctttatttg atacatatcg tcgtgcagat tctcaaatgt
    55201 atgataacaa aaggaaaatt aataaacaat atcaataata aatttaaaaa gtctattctt
    55261 taaataataa atcacaagaa tagacttttt taaatttgtg tttttataag ataaattatt
    55321 taattaaagt ttgttctttt ttctaaacga ttctttataa attcatatat tactttcact
    55381 aatatatttg tgactaatat taacacagct agtgctgctg cctgtgcagt actcccctta
    55441 tcatctagtt gtacaattga tattgcagct acttttgaac ttgcagtata tataaaaact
    55501 aatgctgata ttgtcaccat ggagtttagg aaaaagtaca taaagttctc taaaactgct
    55561 ggcaaacaaa gtggtatagt tacgttctta agaattgatg cgctgtttat tcccattgat
    55621 ttagctacca tgtccaattc tttatctact ttcttaatag cagtagtagc tgttataaat
    55681 gctactgaaa agaaatgaac tatattacat ataaccatta taagtaatgt tccatataat
    55741 ccattaaaca aattcttaat atatattgta tccataaaat taaactctaa tttattaaaa
    55801 aataatacat aagctatacc taaaactaat cctggtaatg ccataggcaa tgtacttaaa
    55861 aaatacccaa atgattttaa atatggagct ttttctgttt tttcattcaa atatgcaaat
    55921 aagaaaacaa agctcgtccc tagaatagct gtcaatagtg acatttttat tgaatttata
    55981 aatggtttaa tcccatcaat actgtttttc atagaaaaat gttccagtgt cagtcttaaa
    56041 tcatatggcc aaactgatat taatgaagat aagattacag ttaacattac agctattata
    56101 ccaaatgcaa taattcctac aacccctcct aaaatactat ctcttaactt attagtttta
    56161 accttatatg gaattgactt tgaagttata taggaatttt gatttttttc aattttttta
    56221 gttactataa acgatattat tgcaggtatt aaaagtaata ttgatacagt tgctcccatt
    56281 ggcatattct gttgccctat aatttgctta tatacatcta ttgataatac attaaactct
    56341 cctcctatca cctttggagc tccaaaatct gtaaaacata atgtaaacga tacgaatgca
    56401 gaacttatta aagagtattt tatacttggt attgttatgc ttataaattc tcttatcttg
    56461 cttatcccca tagtattact agcttcatat agtctataat cggttgaact tagagatata
    56521 taaagtattt gaaatgattg aggaaataca tatataattt gtgccaatat tattcccact
    56581 gctccatata ttggaacatg cactccaagt aaattagtta ccaaaccttg atttccaaat
    56641 aaatatacta gacctattgc atgcatcatt gttggagcaa acataggaaa catagctaat
    56701 gatttaaaaa aacctttaaa tttaatcttt gttctagtta atgcatatgc atatactaat
    56761 gcaagtgtta gtgatattac agttgatata actgatacaa atactgtatt ttttagagaa
    56821 tttaatagag attcagaagc caagtattct tgaaagtttt gtaatcctac aaagactcca
    56881 tctttatcta aaaaagcctg tacaaataga tatattatag gtgctaataa aaatattact
    56941 aaagacataa ctaatactgt aagcatacat ttttttatat ctaaattcat ttttgattta
    57001 agacttatac ttttagaact tatagcatta ttattcatac acttatgctc ctttaacttt
    57061 tggatacttt aaatagtatt tttcgtctat acttattttt acaaggtcac cttctactaa
    57121 atttaaatta acccactctt ttatagaaac atcacttatt atgaaatttt catttaattt
    57181 atcttttatt tcaactctca ataaattccc tctaaactct atatttgata ttatcccttg
    57241 gtagttttct tttgtcgatt tctctatttg aacatattct ggtcttacag ttaatataga
    57301 atctccatta tcaaaacagt ttgtatctcc tataaattga gctgtaaata ggttttgagg
    57361 attttggtat atttcttctg gagtccctat ttgcattata tctcctccat ttagaatagc
    57421 tattttatct gccatagtta tagcttcttc ttggtcatgt gttaccatta ttgtcgttat
    57481 attaagttct ttttgtaatc ttttaatgtc cattctaagc ttgtgtctaa cctttgcatc
    57541 taatgcagac attggttcat ctaaaagtaa aaactttggt tcaagagcta atgctcttgc
    57601 tattgcaatc ctctgttgtt gcccacctga taatgcttta gggtatttat gagcttcatt
    57661 agtcaatcca actgtttcaa gtacttcctt aactttatta tctatttttt cttttgaaac
    57721 ttttctctct tttagtggaa aagctatatt gttataagca gtcatattcg gaaataatgc
    57781 atatgattga aatactatac caaaacctct ctttgatggc tctaaatttg taatatcttt
    57841 atcctggaga attatagttc cactatttac atcttcaaga cctgctatta ttctaagtaa
    57901 tgtagtttta ccacatccac taggtccgag taaacataga aattcccctt cttcaatatc
    57961 caaactaata ttatttaaaa cctttttttg gtcataactt ttaaacacat tatttatttt
    58021 taagtaactc atatcttatc tctccttata tagttatttt tttattttaa attttatatc
    58081 ctactttttc ttctaaaatt ctttcatcta aattattaat ttaaacttta cttactttca
    58141 gattttgaac cgtattttga ttcccaagtt ttaagtactg tacttctgtt tttggcagca
    58201 gagtttaaat caacttcttt tataagctgt tcaaatggtt gtttagaata accttttgga
    58261 actggattat ctgtctttat ggaagtaact gctacttcat gtgcatatct atccatagct
    58321 gaatcactta ttgcccaatc taaaaatagc tttgcttctt tttttatatt atctttttta
    58381 actaaggcat ttgcttctaa gtcccaacct gaaccttcct ttggaaatac aacctctata
    58441 ggttctccac tagataattg ttgtgtagct ctatatccaa gtgtaatacc tattggatac
    58501 tctccagagc cagctaactt cgcaggtttt gaacccgagt gtgtatatgt ggctatattt
    58561 ttatgtaatt tatccatgta attgtaagca tctttttcac ccatcatttg aataagccct
    58621 gatactgtaa gataccccgt tccagatgat gctggatttg gcattgttat aagtccttta
    58681 tattctggtt ttattaaatc ttcataactt tttggaatat ctatacctag tttcttaagt
    58741 tccttataat taactactat tgctgtctct gggacactca ttcctaccca agatacatca
    58801 tcttcagtat ctttaaattt tttatcaact ttatcataat ttttaggctt atatgcttca
    58861 agtgcaccat ctttttttag ctctatcatg ttcattgctg ataatcccca tataatatct
    58921 gcttgtggat tatctttttc tgctaatagt tttgaagcta ttacaccatg agaatccata
    58981 actatctcta catctatatt gggatactct tctctaaaac cttccatata ataagctatc
    59041 tgctcttcct ctagtgctgc atatattgta agtttattat ttccttttcc ttgagtagtt
    59101 tgtggtgttg ttgatatgca acttgtcata aatgtaatca ctacaatgca cagacaagta
    59161 aatataaatt ctttcatatc ttcccccttt gtgttttttc ctttttttat ttgtttttta
    59221 ttgtttttgc ttatgtttat ataatacacc taatttgtta atataaagtt aagtgtaaat
    59281 taacagttcg ttaattttta gaaatttttg ttaaatatat tatttttagt taaatacagt
    59341 ctgtttttaa acaatatatt aatttttata gtatctacat tttaatttaa acataaaaaa
    59401 taagtctaac ctctataaag tagaatgtta gacttatttt tataagtatt taattataca
    59461 accaaatcat tttttttctt ttcttcaagt gcttttttaa gcaccatatc cttaaccttc
    59521 ataagtctag tagtacttgc tctctcattt tcttcaagct tcatagctat atacttaata
    59581 gtctcaatgt aatttggtat cattacattt tcaagagcat taacacgtct acgtgtcttt
    59641 tctatctctt gtgcaagaag ctgtgcactt ttttcacttt ctgcaagtct taaaagtggt
    59701 tgcatagcat ctgagaaagc ttccatagca gaatctaatt cacctgatgt aaaagcaaga
    59761 ccataaggat aaatatcact ttgattgttt tcagttttaa agtcaaacac aggaacatca
    59821 acactcatta tatttctcgt agaaacatct actgaaactg attgctttgg catcataagt
    59881 gctgaaccca gatactcctg actcataact gctcttgcga ttataaagtt tttataagca
    59941 gtatcaagag cattttctgc ttcttcacgc aatcgcttat tttctcttac aatctcaaga
    60001 aattgtttca taagttcatc aagtttatct ttaagaagct tatgacctct tgtagcagtt
    60061 ttaaggagtt tcttaagtct agtcatttcc atacgtgttg gatttatatt taatctagcc
    60121 acagatatca ctccttaggc atatattttt caaaatattc atcacggata cgtttaagtt
    60181 cactttttgg taacatacta agaagcttcc atccgatttc taatgtcttc tcaatagttc
    60241 tatcagttct aaatccttgt gaaacatatt ctttctcaaa ttcatctgca aacttagcat
    60301 acattaaatc aatctcagaa agtgcagatt caccaagtat agccataagt tcttttgcat
    60361 ccttacctct tgaataagct gcaaaaagct ggttcattgt atctgcatgg tcttcacgag
    60421 tcttaccttt accaatacct ttatctttta gacgagaaag tgatggtaaa acatctatag
    60481 gaggctgtat atctttttta taaagttcac ggctaagtat aatttgccct tctgtaatgt
    60541 atcctgtaag gtcaggaatt ggatgtgtct tatcatcctc aggcattgta agtattggaa
    60601 tcatagttat agacccttca tgccctttca tttttcctgc tctttcatac atagtagcaa
    60661 ggtcagtata aagatatcct ggatatccac gacgtcctgg aacttctttt ttagctgctg
    60721 aaacttcacg caatgcctct gcatagtttg taatatccgt tattataaca agtacatgca
    60781 tatcttgctc gaaagcaagg tattctgctg ctgtaagtgc cattctaggt gtagatacac
    60841 gctctacagc tgggtcattt gcaaggttta caaacactac agaacggtcg attgcaccag
    60901 ttgctttaaa atcgcttata aaaaattcag catcttcaaa agttatacca actgcagcaa
    60961 atacaacggc gaacttagaa tcagttccac gtacttttgc ctgtcttgca atctgaactg
    61021 caagattggc atgtggcaaa ccagaccctg agaatatagg aagtttttgc cctctaacca
    61081 atgtattaag tccatctata gcagagactc cagtttgtat aaactcggcc ggataatcac
    61141 gtgctgctgg atttattgga gctccattta tatcaagtct tttatctggt ataatttctg
    61201 gacctccatc aataggtcta cccattccac taaaaacacg acctaatata tctggtgaaa
    61261 ctccaaagtc aagactcttt cctaaaaaac gaactttact ttcagcaagg tttatacctg
    61321 ttgagctttc gaaaagctga acaagtgcag tatctccatt tacctctaga actttgcaac
    61381 ggcgaatttc tccatttgaa agttcaattt ctccaagttc atcaaatttt acaccttcta
    61441 cgccgtttat taacataaga ggaccggcta cctcttgtat tgacttatat tcctttatca
    61501 tagttcttca gcccccctct ttttaataag gtctgcaagc tcgttgtcta tttcatcttc
    61561 aattgaatcg taagctgcat ctatatcgcc ttcttctaca tacttagcac gaccaatctt
    61621 ttcaagaact gaaagcttga taatatcgtt tatagtaaca ttttgcttga tagcatcttg
    61681 tgctgactta tagaatttta atataagtcc catcattcta tattgtttat gaagtgatgt
    61741 ataagtatca acttcatgga aagagttttg atgaaggaag tcttctctta tagaacgagt
    61801 aacctctagt atcaatctat ctccatctga aagtgaatca accccaacca attgaactat
    61861 ttcttgaagt tcagattcaa cttgtaaaag tttcatagct tgagctcttt gagctgagaa
    61921 attatcattt acatttttat ctgcccatac atcaactttt tcctgataga gtgaataact
    61981 agtcaaccag ttaattgctg ggaaatgacg tttatatgct aaagatgcat caagacccca
    62041 gaatactttt actatacgaa gagttgcttg gctgacaggt tctgatgtat caccaccagg
    62101 aggagaaact gcaccaattg ctgtaagtgt tccttctctt tcatccatac ctagacaatt
    62161 tacctttcct gctctctcat agaattgagc aagacgtgaa cctaagtatg caggataacc
    62221 ttcttcacca ggcatctcct ctaaacgacc actcatctct ctaagagcct cagcccatct
    62281 tgatgtagag tctgccataa gtgcaacact atatcccata tctctaaaat attcagctat
    62341 tgtaatacca gtgtatatag aagcttcacg tgcagcaacc ggcatatctg atgtatttgc
    62401 tataagcaca gttctttgca taagtgactc gcctgttctt gggtctttta attcaggaaa
    62461 ttcaagaaga acatctgtca tttcatttcc acgctcgcca cagcctatat atacaactat
    62521 atctgcatct gcccatttag caagctgatg ctgtgtaaca gtttttccac ttccaaaagg
    62581 tcccggtata gctgctaccc caccttttgt gattgggaaa aatgtatcta taactctttg
    62641 acctgtaaca agaagtgaat ctggtgtttt cttttctcta tatggtcttt cttttctaac
    62701 tggccatttt tgcatcatag ttacaggtat atcattacct ttttcatctg taataacaca
    62761 aactgtatct tcaacagtaa attcaccaga atatatttct tttatagtac ccttaactcc
    62821 ataaggaacc ataattttac attctactac tgctgtttct tgaacgccac caattatatc
    62881 tcctgctaca accttatcac caacagattt tttaggttta aattcccact tagttgttct
    62941 atcaagtgaa gatacttcaa cacctttagt tatattagta cctgaaatat catacatttt
    63001 ttcaagtgga cgttgaatac catcataaat agttgaaata agacctggtc caagttcaac
    63061 actcataggc attccaagag aaactacttc ttcccctggt cctagaccgg aagtttcctc
    63121 ataaacctgt atagaagctt tatctccatg catttctata atctcgccta taagatgttt
    63181 atctgaaact cttacgacgt caaacatatt cgcatctctc atgccctccg ctacaacaag
    63241 cggtcctgac acctttacaa ttgtgcctgt tttcatattc tctcacctgc aatcatatac
    63301 tttatcaaaa tttaaatatt ccctcctata ttttattagc acatatattt agcaccaata
    63361 aaatttgaga ttgtctttta ttcaactttc atctattctt taaataatat atctgcacct
    63421 atagcacgtt tactagattc tcttacttca ttcataccta atcccatact tcctccaata
    63481 cctggaataa ctataatggc aggaagttgg taatctttgt attttgctat tgattctttt
    63541 gcaagcaatg atgcctgttc tgtaatataa attatcgcat attcatcttc aaccaactta
    63601 tgtatacttt ttttaatttc gtcactatca taggctggga agatatctat tccaagagct
    63661 aaaaatccca tgatgctatc tttatctcca actactccta ccttatacat aagcatccct
    63721 tagcctttct tttatagtat ctgcgtctat attattaagc ttactagtca aaataattct
    63781 aattgttttt atctctgatt ctttagcata taaatatgca attagtggtt ctaatgtaag
    63841 aggcttaaat tttgctcctc taacatattc cataagatag tcatcacaaa gtttttcaaa
    63901 gacagtaaaa ccactatcca tgccattttt acagacatca gagtaagaag tagatttaaa
    63961 acatgatgct ggagtatctg aggaaaaagc ttctaagaat ttttccttat caagtgagcc
    64021 acctgaaaca aacacattca taaacatatc aaaatctttc ttcatatttt tgactcttat
    64081 aaaactcttt agatttgtta aatcacaaac tttcataaca taatctatta caaatttgtt
    64141 ttggctttct ttagcagttt ctttcatact ggtaaaggtt gctttatcta gaacaatatc
    64201 aaccatctgg ccattttgtg tcttattata aacatcaaat gcctctaata tagctgatga
    64261 cattatctta ggtaaatcac taaaactacg atttgctaaa gattctctaa gcttaataag
    64321 aggaattgta cctccatcaa ttaaatattt ctcaccatct acaccagaaa tttcttcttt
    64381 aatcagcact tttaaattgt gatagtcatt tttataaaga aatacatcaa caaatttttc
    64441 ttcaggagct agacttttaa gaatttcata tgtctttgat aattcttgag tcaaaatatt
    64501 ctcaaaatta tgtatattat tatttgatgt atcagcataa cctgcctcag ctataattct
    64561 taaagagtct tcagggcttt tggcttctgc catttgaata aacatttgtc tgttaagaag
    64621 ctgtttttca agcactctta ttcgtgcaac ggcataggga taagtttttt cttctgccat
    64681 tttttaatcc ctccttaatt aaacaaaatt tctgctgcaa tttgttcaat atattcatgc
    64741 tctactgcaa ttatggcttc aaatgaataa ttgtactcaa tgtcaccttt tttaactatg
    64801 aaacctccag taatatctct agtttcatca gacactttaa tgcctttttt tgatagcaca
    64861 tcttttaatg tttttttatc ttttttagat aatactatct ctgaatcatc tgtacaattt
    64921 gatttttcaa tcatgtttag tataatcttt tcatattcat tatctttaag atttaaaagt
    64981 ttgtttttag cttctaaaat tacctcttct aaaatctctt gtttttttga taatatttgc
    65041 tttttagcct ccatataagc tcctgatatt tccttagaag ccgctttttc tgcttctgcc
    65101 tctgcaagct ttgtatagga agccatttcc ttttcagctt tttcattagc tgaatttact
    65161 tttaaatctg cttcactttt agctttatcc aatatttctt gtgcttcttg tttggcatca
    65221 gctataattc tgtcaatcat tttttgttca ttacccatag gagtgcttcc tccttttcat
    65281 tttttttact tatgaattat aatttataat taaccaattg caattccatt gtaagctaag
    65341 aaagaaacaa gtagtcctaa aagagcatat gtttcaacta ttgctgcaaa tgttatagct
    65401 ttaccaagtt cttcaggtct ttttgcaact attccaactc ctgctgctgc tgctttacct
    65461 tgtgctatac ctgatactaa accaactaaa ccaattggaa gtcctgccat aagaagttgt
    65521 aaaccttgag ctgatgttgg tattgcatct ccaccaataa tccctgcttt tgataaaata
    65581 aggaaagcta tgataaatcc atacagacct tgtgtaccag gaagaagttg taaaactaga
    65641 agttgaccga atttactagg gtcttctgtt acaacacctg ctgcggcttg acctgctatt
    65701 gaagtacctt tagcagaacc catacctgca aataatgctg ctatagcagc tcctgatatt
    65761 gccaaaaatt gaccatttcc taacgcgttt aaaaattcca tatttacatc tcctttttat
    65821 taatgcttgt atattttgtt ttatacttaa acggaacaaa aggaactcct ccgccttcat
    65881 aaaacttatt gaaaaattct acatactgta acctacttgt atgaacatat gcacctagtg
    65941 catttataag aaggtttatt gtgtgtccta caacaccaat tacaactgca agtatcggac
    66001 cagctatagc tcctaaaagg ttgataactt gtgctataac tcctgttgtt aaacaaagcg
    66061 ccataattct tgtataagat aatatatcag caaaataact tgttatacca tagagacttg
    66121 aaaatccttt aaaaagctta acaggaatac ctttaaagct tcttccttga gtaagtacaa
    66181 gacctatagc acctataatt gctaaatatt ttcctacttc tgaaaataca cctatgtccc
    66241 ctgcaacaaa aggtattata agtagacata cacctgttat acacaaatac caaaaaccta
    66301 tgtcaaagat tgcatctatt acctttccac ttcttattaa tgtatatgct tttattccca
    66361 aacctacata tatatggata ataccgaaca gtaacgacat tcccataagt gtcataacat
    66421 cctctaaagg attaattaat gcttttatag gaattaaatc ccccaaaata cccccgaata
    66481 taagacccca tacagtagtt gaaactccac agataccaat aagtttaatt aaatttcctt
    66541 cacctttttg tatctttaat ttatatacaa caaatccaca aactactgca attattaacc
    66601 catatgcggc gtcacttagc atcattccaa agaatataac aaagaagaaa gttaaaattg
    66661 tatttgggtc aatatctttt gtacttggat agctgtacat gttagttaca ctttcaaaag
    66721 gtgttactaa tttattgttt tcaagcagaa ttgggaagcc ttcttcttta cttccttctt
    66781 cagtctgaac acaacaatca aacttttctg taatttcttt aattaattca tctgcccttt
    66841 tgcttggtaa ccaaccatta agacagaatg ttgtttttgt tttgacaagt ctctctataa
    66901 tctttttttg gtctctttct atagtgtaaa aatcatatag gttttcaagc atgtgtatac
    66961 tatctgcatg tcttttaatt tcctctgttt tgtccttaga aacgttttcc tgtctaatta
    67021 tcatttcatt gtatttcttg atagcttgta acggtgtacc ttcttcattt ggtaatgaaa
    67081 ccactgaaaa attaaattct tttaaaactt ctaaaacatc atcaaaagtt tcttttaaag
    67141 taattaaata aacatagttc attaacttgt cagaattgac aatcccaata acactttctg
    67201 gtatttcatc ttctaatttt actcttaaag catcaatgtt tgcgcttatg ggcacagttc
    67261 caagtatagt ttttgtatac ttagtttcca tattttcaat aggaatatca aagttcaccc
    67321 atggttctaa catactttta ttgttgttaa gtaagtttat gttagacctt attgtaccta
    67381 tctccttgtg caaattgttt aactccagag cttcagcata aacttgccct tctttttcac
    67441 tatcaatttt gttaaactct ctttttggtg caagtaggga ttttttttgt ttcactagtg
    67501 aagaaacaat attaattgct tggtttacat gagacatttt ctgctctagc attataactt
    67561 cagattcttc actatctttt acaagataat tttttaattc ctcctcctca gtaagaaagg
    67621 cactatcatc aatctgaaca aacccacggt tcataagtag ctttaaaatc tggctttttt
    67681 gagcttctaa gccaacaata gatattttgt tcatattaac tattgccata ttatctcact
    67741 acctttccaa taaccgcttc aatagcctta ctttttcttt cttcagcagt tttttcaatt
    67801 ttcagacatt cacttttagc attagctaag attttatcaa cctctgctct actgtcggtg
    67861 actgccttct caataagagt ttcttccata agctttgctt gtttttttac atcagcaaat
    67921 atgctttcac atttgtttac agcatcagct ctgatagact ctgcatcagt aacagctttt
    67981 actttgatac tgtctgctgt ctgctctgcc tcaacaatgc tttttattat ttcaaaagcc
    68041 atccaaatca cctctcttac ctttttacta tgtatataac caattagatt tttttattct
    68101 aattagatta ctacctcatt gttaaagtat aaacagcatt tttatataat aattaatatt
    68161 tttcaacgtt tatttcttaa taaaacatat tttagaatag tacttgccta gatttacatc
    68221 cttttttgac ttacttttag actatgacat gagtatggtt tttaaatacc attattttca
    68281 ataattataa tttaaagcga tatagtttgt caatagcgtt attttgtttt aaaattaacg
    68341 ttatgtcgac attttaaatt tttattttat tttttttata attttaattt aatttattac
    68401 atataaaagt tttttatatt ctttttcaac ctctaaccat tgaagtttat tgtttttttt
    68461 gaatttttag aaatatctcg cactatttta tctaactttt ataaatcatc aagctatatc
    68521 gatttttgtc accttatttt taatctaatt tttttatatc tagttagaaa taaatcaata
    68581 tttttaaaga ttgataaaac ttacacctag ttctaatagt tttattttaa ggcaatgtat
    68641 taatcttaag tagataatat cattagttac tctatatatt cgacaacatt ataaaaaaat
    68701 cctcgtacca atcactccaa tcttcaatag gatatgctgc tcctccattt acacttttca
    68761 gtagattgga tgtatattct tctcccatag aaaaaagttc ccctactgtc atatcataac
    68821 ctctagatgt aacaacctta caaaatgaat ccataacatc acgttgttct cttgttttta
    68881 taagttcctt tctaaattca tcatcattct tagcttcttc taaaatttta gttaattttt
    68941 cattcattat gtatttctcc ttttaagtag tctttctgta aacttcaata agctttatat
    69001 aaaaaggaag ccatcctaaa tagactaaga tgacttcgct taactgttag caacacattt
    69061 actagtataa aataattggt gtacctggtt ctatattttc atatattttc tttgccttag
    69121 aaaaaggtgt atttacacat ccatgtgaac ctgaagactt atatatactt ccaccaaaag
    69181 aatttctcca agtagcatca tgaatgccta tgttcccatt aaatggaagc caataactta
    69241 caggtgaact gtaaccttga ccagttaatg aaacatttct agccttataa ttaagaggat
    69301 atatacctga tggtgtagca aatcctctag ctaaatcacc tgttacaacg tctgttgata
    69361 caagcatttc tccattttta aagaaccaca tatgttggcc agaaagacta atctctacat
    69421 atgtatttcc aatatcatct ttattacgag atacagcttt ttgtatgtaa ataggttctc
    69481 ttgtaacatt tttaccagct tttacaacat caactaatgc ttcagcttct ttctttttat
    69541 ctatcaacca accataaatt ccacctgaaa ttgtaatatc tttacctgtg gcagttttaa
    69601 atggtcttga gtcaccaaaa gtactgtatt ttttacttaa acctcttgta tattctacca
    69661 tagcatcatt atcaaaagtt atgtcataat tcttttctga gtctactttt aaccatttat
    69721 taatttcaga accatctaaa gtttccttac ggtcactaaa atcatatgta acgactacac
    69781 caacatactt atctaatgtc ttaatagctt gtttcaactt ttctgaatcc tttgtgttgt
    69841 ttggtgcttc ataaacttta ctttcatcca gagaaataga agtattccca gaattaattg
    69901 agttttgtac taacttataa aaatcatctt ttttcacttt gtttccaagt acctctggta
    69961 ctataacata agcgttttta gtgctatcat acttaggata agcactctta ggttctacaa
    70021 catttttact atcaaagcaa gatagagcgt taaatctttt ttctaataaa tctttattat
    70081 atgaaagatt taccatatta ttatactctt tagacttaaa tattccacca atccatccaa
    70141 tagcgctctg actatctttt atcttttgaa ctttatcatc tggtgtaaat tttaaatcaa
    70201 tatcttttgc ttttatttgt tctttcttat tgtttctttc ctctaagttt aaagtatagg
    70261 aatttgtact agatgttaac aaatcattta cttgctcaac tgtttttcct gaaaccttta
    70321 cgccattaat agtcgttcca aagtaaaaat gatttctaaa aaagattgcc attcctatat
    70381 aagctacaaa caaaacacct actactatag ctatcttaaa ttttagattt ttttgtccac
    70441 tttcttgttt tacctctttt ccatcaatca taattaaatc cttccttaca ttgtaattac
    70501 ctatgtacct tattggtttt taaacaaaac catgtatgcc ttattttata tacccaaatt
    70561 actgtatcat tatttatatt tttaaatata tagttatttc cataaaacca ttttatcttt
    70621 tagataaaat gattattata aatcccccct ttcaaaatcc cttaaacaca atctctgcta
    70681 tattaatata ttaccatact tttaataatc gtgggactat ctatctattt ttgtaacact
    70741 aaactactct tttaaaaaag aaactaattt tgtgttagtt tctttatctt aacttatttt
    70801 tatattgaat tttagcttaa cataacgttg ttatatagat tctatttaat tattttagtt
    70861 tctatatctt ttccatctgc atattcttta agtaattcct tagcatatcc aaaatattct
    70921 tcaatatcag attcttgact aaaagaaaat atacaaatta atatttcatt tgcatcttct
    70981 gttatcattg ctctttcaga atcactagtt ggactcccaa atttacccac tgaatcagac
    71041 aatataggaa gattttctat atttattaat tctttcccaa tacccttata ctgttctcct
    71101 tcatctccta cagtaaaaca tactggtgaa tgtaatttgc ttacattata tgtacctact
    71161 ggatataatg attttattga tattaaattg tttatttcta ctatattatt tattgtataa
    71221 agacccttcc cttgaataat tcttctaacc aatgcttccg aagatgttct atatctactt
    71281 ggattttttc caagctcttt ataagcattt cttgcatctt taattttatc tagtttcgta
    71341 atgtcttcaa cttttagact ttgatttata gtatcacaaa actcatttat ttcattaatt
    71401 aatttttctg agcttttatt tactgctact tttgcttgaa tgcaacccag cttagcatta
    71461 ggccatcttt ccttaagttt gtcatcaata cttacatcta tcatacttaa acaactccta
    71521 tacactaaat ttttattaaa gtttttatca tctatacatt atagtactat tcttttgtta
    71581 ataacatgtt tattagcaaa ataaatttat ttttaatata atttttataa aatacaatta
    71641 ttttttgctt tatattagac aatacattga taaaataaaa aaacactaat tatttagcag
    71701 tgatttatta aaatcaagca ttcataatag tgctttatat aaaaatcaaa ttttgtttta
    71761 aagtaaatct aaaaaattct tagctggcat tggtcgtgca aaataaaatc cttgaactaa
    71821 atcacatcca aattgtttca ttaactcagc ttgttcttta ctctcaacac cttctataat
    71881 tacaactaaa tctagtgatt ttgctagaga cactattgat tttgctatat tgcgacttct
    71941 ctcatcatgt tcaatgccac caagaaaaga cttatctagt ttcaatatat caattggcat
    72001 atctcttaaa caactaatag aagaatatcc tgtgccaaag tcatccatag aaatagaaaa
    72061 tccatgcttc ctcaattcat ttaaaacatt ctttaaaata tttaactcat taatagccac
    72121 agtttctgtt atctctattt caatgaaatc tgaacttaga ttatacattt gtattgtttt
    72181 attgataaat tttacaatat ctggttgata caactcgact ctagataaat ttactgaaac
    72241 tggaactatc tttttacctt gctttttcca ttcagataaa tcattgcaaa ccctttcaaa
    72301 tacaaatctc ccaattttta aaatcaactt acttttctct gctattggaa taaatactgc
    72361 gggacttata aaaccatgtt ctggatgatt ccatcttatt agtgcttcac tccctatcat
    72421 ttctccagtt acaagtgaaa acttaggttg ataatacact tcaaattgat tttttaccaa
    72481 tgctattttt atatcatcta aaatcattga ttcttcacta agcttattcc taacatcttc
    72541 attataaata gcataattta tatttttacc tttagcaaca gacctagcca tatttgcttt
    72601 atttacagcc ttttgaatat ctacttcacc ttcttcaaca aaataaatac ccacacacag
    72661 agagatttca aagactatac tcaaattact ttcaatatta cttcgtatat tatcaagttt
    72721 tcttataatt ttatttcttc catttttata atcacagaaa attgcaaaat aatcacttga
    72781 aagtcgtgca tatacctcac cttctgttaa ttcttctttt aaagcttttg ctattgtaat
    72841 taataaattg tcaccaaatt catatccaaa agtatcatta atcatcttaa agttattaat
    72901 atcaaaatat actataatat aatttaaaga tggtttatct aaaagatact tactacactc
    72961 tctataaaat ttattttgat ttcctatata tgtaacttta tcttcataag ccaaacttaa
    73021 tatttctttt tcattagatt tttttatata aattatataa aaaataattg caacaaatat
    73081 taatacaata gataacactg catatacagc tctgttgatt atttgttttg aattactaaa
    73141 tacaacagtt tctggaattg aaaaaattaa attccagtct tttatatagt tattttcact
    73201 attcccatta tccatagtgg catatcctaa atatcttctt tcttccaaca tatttaatac
    73261 agttgcacct gttttatttt cttgcaattc tttttttaat ctatttactt cttgaatatc
    73321 attatcctgt tctaacaatt tataaatatt ttttgatagg ctatcccctt gtggatgaag
    73381 gataattgta ccatcatttt ttacaacata agatatacta ttattttcat aaaaagatat
    73441 attaataagt ttcatcagag tattgatatt gtaagtacaa tataaaactc caactacttt
    73501 atcattattt aataatggta ctgaaatagc aatcttcttt atagacttat ttacttcatc
    73561 aacatatgga cttgaaacat acttcttacc tttaattgag tttttgaaaa attctctatc
    73621 tttcactgaa aacttatcac ctttggtatt ttcagcatta ccatttatat caactattgc
    73681 catagtgtaa aatttttgat tttccatttc atctaaaaga tttttcattt tttcctcatt
    73741 aggtatatct ggatttgaag cataatagtt agaaaaaata tttaaaacat ctaaatcttt
    73801 ttcaatttgt ctttgtgcta gttgagagcc ttgtactgca acttctttta tatgtatttt
    73861 tgcctctgac ataagaagat gttttgtatc ttctatatag atatacccca ttgtcaaaaa
    73921 taatgatgtt aaaaaaagaa ttgtaattaa tgtaaaactt ttatttctcc ctgtcattcg
    73981 actcctcccc taattagtca atacttcata tagataatat atccttttta taccaattca
    74041 tcatttatat tgtatataac tattcttaaa tgttacacat aaaatcaaca taataaccat
    74101 aaaaacattc ttttattatt ataataacac tatttaattg aattttaaat taaagaataa
    74161 aaactatcca ttttctcaaa caaaaaaact cttatacaat aaaactttgt tttatgtata
    74221 agagttttta ttttatctat tttatagcaa acttatcttc cataatatga atttaaatac
    74281 atatctttta tttcattcat aagtggatat cttggatttg ctcctgtaca ttggtcatca
    74341 aatgcttgaa ttaccatttc atctattgaa tccataaact tagattcttc aactccaaac
    74401 tcttttatag atttaggaat accaacttta agttttaaat cttcaatagc taccaataaa
    74461 ctttggaatt tctcttcatc agaatttcct tttaatccta aaaatgaagc tatttcagca
    74521 tatctcttta atgcttctgg atatttatat tgagagaatg ctcccatttt ctttggtgca
    74581 tctgaagaat taaatttcat aacttctgtt atcaaaagag catttgcaac accatgtggt
    74641 acatggtgga aagcacctaa tttatgagcc atagagtgac aaacacccaa aaatgcattt
    74701 gcaaaagcca tacctgccat tgtagaagca tttgccattt tttctctagc ttctgggtct
    74761 tttgcaccat tatcatatgc acgtggaaga tattcaaata tactcttaat agcttgtaaa
    74821 gctaatccat ttgtataatc ggttgcaagc atagatacat atgcttctaa tgcatgagtt
    74881 aaagcatcta taccagaagc agatgttaag ctttttggca tattcatcat catatcagaa
    74941 tcaactatag ccatatttgg catcagttca taatctgcta atggatattt tactcctgta
    75001 tcttggtcag ttataacagc aaatggtgtt acttctgaac cagtacctgc tgatgttggt
    75061 atagctacaa aattagcttt ttcacccatt ttagggaatg tatataccct ttttcttata
    75121 tccataaatc tcatagctag gtcttggaaa tctacatctg gatgctcata caatgtccac
    75181 attatctttc ctgcatccat tgcacttcct ccacctatag atattattac atctggatta
    75241 aattctctca tagctttagc gcctatctta gcacattcca aagttgggtc tggttctact
    75301 tcaaagaatg tagtgtgctt aatattcatt tcatctaata aatcagtaac tgctttagta
    75361 tatccattat tataaaggaa tgtatctgtt acaataaaag ctctcttctt attcattaca
    75421 tctttaagtt cttttaatgc tactcctaaa caaccttttt tgaaataaac tttttctggt
    75481 gctctaaacc aaagcatatt ttctctcctc tcagctactg ttttaatatt aagtaaatgc
    75541 ttaactccta cattttcaga tactgaattt ccaccccaag acccacatcc taaagtaaga
    75601 gaaggagcta gtttaaaatt atataagtcc cctataccac cttgagaaga aggagtatta
    75661 attaaaattc tacaagtttt catggctgaa gtaaacttat caagtttttc tctttgattt
    75721 acatcatcaa tatataatga agatgtatgc ccaaatccac catcttctac taatttttct
    75781 gcttttctaa ctgcatcatc aaaatcactt gccttgtaca ttgcaagtac tggtgaaagt
    75841 ttctcatgag caaaagcttc ttctatttca actgattcta cttcacctat taaaacctta
    75901 gtatctactg ggacttcaaa gcctgcaagt tttgctatag tacaagctgt ttgcccaact
    75961 attttagaat ttaatcctcc atttactaaa attatatttc ttattttttc tgtttcatct
    76021 ttatctaata aataagcacc acgctcttta aattcttttt tgacttcatt gtatatattt
    76081 tctaatacta taaccgattg ttcagaagca catatcatac cattgtcaaa agtcttagat
    76141 acaagaattg agtttacagc agtttttata tctgcactat catcaattat tgctggagta
    76201 ttacctgcac caactccaat agctggtttt ccagatgaat acgctgattt aaccattcca
    76261 ggacctcctg tagcaagggt caaatccact tctttcataa cagttgtagt taattctaaa
    76321 gatggctcat ctatccatcc tattatacct tcaggagctc cagctaaaac agcagcctca
    76381 agaacaactt ttgcagcctc tatagtagaa ttttttgctc ttggatgtgg agagaaaatt
    76441 attccatttc tagtttttaa agctaaaagt gctttaaaga tagcagtaga agttggatta
    76501 gttgtaggta caactgctgc aataacacct attggctcag caattttagt cataccaaat
    76561 gcttcgtctt tctctataac accacaagtt ttagtttctt tatatgcatt atatatatac
    76621 tctgaggcat aatgattctt tataacctta tcttcagcaa ttcccatacc agtttctttt
    76681 tgtgccatta tagctagagg aactctttgc ttattagctg ccaaagatgc tgctaaaaaa
    76741 attttatcta cctgctcttg actatatgta gcaaatattt tttgagcttc tctgattttt
    76801 gctagttttt taactaagct ttcaacgtta tttacagtat ctaaaccaac tgacataact
    76861 tcattttctt ttttattttc tattattact tgttctttat gagccatttt aacaacctcc
    76921 tgagatagtt ttttatttat tatgttaatt tattaacatt atagcattta ctttttctat
    76981 tttcaagtta tttttttaac attttatttt ttatctaata taacaccatt tctactaata
    77041 atatctagct ttacaaatac ttaatttaac tagatatcac tttatttttt acgcaaatca
    77101 ctaatgaaat catctaaaaa cttaaggata acgttatttt tttaacgttt atatttttgt
    77161 attttttaca aataaaactt tataaaaaga atttttaata tgatactcta tcaagtttaa
    77221 aaataaaaat acttgaaaat aaaaataaaa acttaattaa caagttaaag taaatatagt
    77281 taaatgtaca aacat
//
LOCUS       DAEPXW010000005        72975 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.005, whole genome shotgun sequence.
ACCESSION   DAEPXW010000005 DAEPXW010000000
VERSION     DAEPXW010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72975
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.005"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            200..1396
                     /locus_tag="KRM55_000300"
     CDS             200..1396
                     /locus_tag="KRM55_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBH1592573.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1489..2013
                     /locus_tag="KRM55_000301"
     CDS             1489..2013
                     /locus_tag="KRM55_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBH1592574.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            2038..2214
                     /gene="rpmF"
                     /locus_tag="KRM55_000302"
     CDS             2038..2214
                     /gene="rpmF"
                     /locus_tag="KRM55_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBH1592575.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2421..2978
                     /gene="fapR"
                     /locus_tag="KRM55_000303"
     CDS             2421..2978
                     /gene="fapR"
                     /locus_tag="KRM55_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBH1592576.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2989..4011
                     /gene="plsX"
                     /locus_tag="KRM55_000304"
     CDS             2989..4011
                     /gene="plsX"
                     /locus_tag="KRM55_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBH1592577.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            4037..5023
                     /locus_tag="KRM55_000305"
     CDS             4037..5023
                     /locus_tag="KRM55_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBH1592578.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5132..6061
                     /gene="fabK"
                     /locus_tag="KRM55_000306"
     CDS             5132..6061
                     /gene="fabK"
                     /locus_tag="KRM55_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBH1592579.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            6077..7027
                     /gene="fabD"
                     /locus_tag="KRM55_000307"
     CDS             6077..7027
                     /gene="fabD"
                     /locus_tag="KRM55_000307"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBH1592580.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAILGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            7027..7776
                     /gene="fabG"
                     /locus_tag="KRM55_000308"
     CDS             7027..7776
                     /gene="fabG"
                     /locus_tag="KRM55_000308"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBH1592581.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7830..8054
                     /gene="acpP"
                     /locus_tag="KRM55_000309"
     CDS             7830..8054
                     /gene="acpP"
                     /locus_tag="KRM55_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH1592582.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            8083..9321
                     /gene="fabF"
                     /locus_tag="KRM55_000310"
     CDS             8083..9321
                     /gene="fabF"
                     /locus_tag="KRM55_000310"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBH1592583.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9547..11265
                     /locus_tag="KRM55_000311"
     CDS             9547..11265
                     /locus_tag="KRM55_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1592584.1"
                     /translation="MNFRLPKKRLPKKIIFICIVLISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11296..13296
                     /locus_tag="KRM55_000312"
     CDS             11296..13296
                     /locus_tag="KRM55_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1592585.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13647..13892
                     /locus_tag="KRM55_000313"
     CDS             13647..13892
                     /locus_tag="KRM55_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH1592586.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13927..14652
                     /locus_tag="KRM55_000314"
     CDS             13927..14652
                     /locus_tag="KRM55_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH1592587.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14674..15987
                     /locus_tag="KRM55_000315"
     CDS             14674..15987
                     /locus_tag="KRM55_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1592588.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            16193..16732
                     /locus_tag="KRM55_000316"
     CDS             16193..16732
                     /locus_tag="KRM55_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1592589.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16821..18806
                     /locus_tag="KRM55_000317"
     CDS             16821..18806
                     /locus_tag="KRM55_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HBH1592590.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGIKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            19030..19998
                     /gene="spoIIIAA"
                     /locus_tag="KRM55_000318"
     CDS             19030..19998
                     /gene="spoIIIAA"
                     /locus_tag="KRM55_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBH1592591.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19988..20509
                     /locus_tag="KRM55_000319"
     CDS             19988..20509
                     /locus_tag="KRM55_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBH1592592.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20526..20723
                     /gene="spoIIIAC"
                     /locus_tag="KRM55_000320"
     CDS             20526..20723
                     /gene="spoIIIAC"
                     /locus_tag="KRM55_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBH1592593.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20739..21125
                     /gene="spoIIIAD"
                     /locus_tag="KRM55_000321"
     CDS             20739..21125
                     /gene="spoIIIAD"
                     /locus_tag="KRM55_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBH1592594.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21210..22415
                     /gene="spoIIIAE"
                     /locus_tag="KRM55_000322"
     CDS             21210..22415
                     /gene="spoIIIAE"
                     /locus_tag="KRM55_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBH1592595.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22475..23092
                     /locus_tag="KRM55_000323"
     CDS             22475..23092
                     /locus_tag="KRM55_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBH1592596.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23104..23658
                     /locus_tag="KRM55_000324"
     CDS             23104..23658
                     /locus_tag="KRM55_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBH1592597.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23685..24374
                     /locus_tag="KRM55_000325"
     CDS             23685..24374
                     /locus_tag="KRM55_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBH1592598.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDESDSSKTEDSSNIDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24484..24846
                     /locus_tag="KRM55_000326"
     CDS             24484..24846
                     /locus_tag="KRM55_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH1592599.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24931..25437
                     /gene="nusB"
                     /locus_tag="KRM55_000327"
     CDS             24931..25437
                     /gene="nusB"
                     /locus_tag="KRM55_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBH1592600.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25421..26491
                     /locus_tag="KRM55_000328"
     CDS             25421..26491
                     /locus_tag="KRM55_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBH1592601.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGYNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSVKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26488..27693
                     /locus_tag="KRM55_000329"
     CDS             26488..27693
                     /locus_tag="KRM55_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBH1592602.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27695..27910
                     /gene="xseB"
                     /locus_tag="KRM55_000330"
     CDS             27695..27910
                     /gene="xseB"
                     /locus_tag="KRM55_000330"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBH1592603.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27913..28800
                     /locus_tag="KRM55_000331"
     CDS             27913..28800
                     /locus_tag="KRM55_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBH1592604.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28830..29267
                     /locus_tag="KRM55_000332"
     CDS             28830..29267
                     /locus_tag="KRM55_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBH1592605.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29301..31166
                     /locus_tag="KRM55_000333"
     CDS             29301..31166
                     /locus_tag="KRM55_000333"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBH1592606.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDEGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31299..32111
                     /locus_tag="KRM55_000334"
     CDS             31299..32111
                     /locus_tag="KRM55_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HBH1592607.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32131..33810
                     /gene="recN"
                     /locus_tag="KRM55_000335"
     CDS             32131..33810
                     /gene="recN"
                     /locus_tag="KRM55_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBH1592608.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            34024..34890
                     /locus_tag="KRM55_000336"
     CDS             34024..34890
                     /locus_tag="KRM55_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592609.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVTVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECVIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDGIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34983..35474)
                     /locus_tag="KRM55_000337"
     CDS             complement(34983..35474)
                     /locus_tag="KRM55_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1592610.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35535..35975)
                     /locus_tag="KRM55_000338"
     CDS             complement(35535..35975)
                     /locus_tag="KRM55_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1592611.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36136..37194
                     /locus_tag="KRM55_000339"
     CDS             36136..37194
                     /locus_tag="KRM55_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH1592612.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37336..38160
                     /gene="spo0A"
                     /locus_tag="KRM55_000340"
     CDS             37336..38160
                     /gene="spo0A"
                     /locus_tag="KRM55_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBH1592613.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38573..39694
                     /locus_tag="KRM55_000341"
     CDS             38573..39694
                     /locus_tag="KRM55_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592614.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39712..40587
                     /locus_tag="KRM55_000342"
     CDS             39712..40587
                     /locus_tag="KRM55_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBH1592615.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40611..41303
                     /locus_tag="KRM55_000343"
     CDS             40611..41303
                     /locus_tag="KRM55_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1592616.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41311..42135
                     /locus_tag="KRM55_000344"
     CDS             41311..42135
                     /locus_tag="KRM55_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH1592617.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42140..43207
                     /locus_tag="KRM55_000345"
     CDS             42140..43207
                     /locus_tag="KRM55_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBH1592618.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43209..43745
                     /locus_tag="KRM55_000346"
     CDS             43209..43745
                     /locus_tag="KRM55_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1592619.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43813..44418
                     /locus_tag="KRM55_000347"
     CDS             43813..44418
                     /locus_tag="KRM55_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBH1592620.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44430..45344
                     /locus_tag="KRM55_000348"
     CDS             44430..45344
                     /locus_tag="KRM55_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1592621.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45386..46558
                     /locus_tag="KRM55_000349"
     CDS             45386..46558
                     /locus_tag="KRM55_000349"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBH1592622.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46605..47417
                     /locus_tag="KRM55_000350"
     CDS             46605..47417
                     /locus_tag="KRM55_000350"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBH1592623.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47621..48946
                     /locus_tag="KRM55_000351"
     CDS             47621..48946
                     /locus_tag="KRM55_000351"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBH1592624.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49159..50238
                     /gene="mltG"
                     /locus_tag="KRM55_000352"
     CDS             49159..50238
                     /gene="mltG"
                     /locus_tag="KRM55_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBH1592625.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50410..51084
                     /locus_tag="KRM55_000353"
     CDS             50410..51084
                     /locus_tag="KRM55_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBH1592626.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            51071..52318
                     /locus_tag="KRM55_000354"
     CDS             51071..52318
                     /locus_tag="KRM55_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH1592627.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52390..54054
                     /locus_tag="KRM55_000355"
     CDS             52390..54054
                     /locus_tag="KRM55_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBH1592628.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54151..54792)
                     /gene="sigK"
                     /locus_tag="KRM55_000356"
     CDS             complement(54151..54792)
                     /gene="sigK"
                     /locus_tag="KRM55_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigK"
                     /protein_id="HBH1592629.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTP
                     REREIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            55359..55721
                     /locus_tag="KRM55_000357"
     CDS             55359..55721
                     /locus_tag="KRM55_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592630.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSKIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            55705..56421
                     /locus_tag="KRM55_000358"
     CDS             55705..56421
                     /locus_tag="KRM55_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592631.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEYEEELKQNIIE
                     NIKKNFDEKNLVQVYKYRGV"
     gene            56441..56860
                     /locus_tag="KRM55_000359"
     CDS             56441..56860
                     /locus_tag="KRM55_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592632.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            56850..57374
                     /locus_tag="KRM55_000360"
     CDS             56850..57374
                     /locus_tag="KRM55_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592633.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            57686..58243
                     /gene="efp"
                     /locus_tag="KRM55_000361"
     CDS             57686..58243
                     /gene="efp"
                     /locus_tag="KRM55_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBH1592634.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            58335..58790
                     /locus_tag="KRM55_000362"
     CDS             58335..58790
                     /locus_tag="KRM55_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1592635.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            58953..59663
                     /locus_tag="KRM55_000363"
     CDS             58953..59663
                     /locus_tag="KRM55_000363"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBH1592636.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            59717..60787
                     /locus_tag="KRM55_000364"
     CDS             59717..60787
                     /locus_tag="KRM55_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1592637.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            60815..64369
                     /gene="smc"
                     /locus_tag="KRM55_000365"
     CDS             60815..64369
                     /gene="smc"
                     /locus_tag="KRM55_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBH1592638.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            64396..65676
                     /gene="ftsY"
                     /locus_tag="KRM55_000366"
     CDS             64396..65676
                     /gene="ftsY"
                     /locus_tag="KRM55_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBH1592639.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMNSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            65779..66147
                     /locus_tag="KRM55_000367"
     CDS             65779..66147
                     /locus_tag="KRM55_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBH1592640.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            66144..67496
                     /gene="ffh"
                     /locus_tag="KRM55_000368"
     CDS             66144..67496
                     /gene="ffh"
                     /locus_tag="KRM55_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBH1592641.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            67534..67806
                     /gene="rpsP"
                     /locus_tag="KRM55_000369"
     CDS             67534..67806
                     /gene="rpsP"
                     /locus_tag="KRM55_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBH1592642.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            67871..68098
                     /locus_tag="KRM55_000370"
     CDS             67871..68098
                     /locus_tag="KRM55_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBH1592643.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            68206..68721
                     /gene="rimM"
                     /locus_tag="KRM55_000371"
     CDS             68206..68721
                     /gene="rimM"
                     /locus_tag="KRM55_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBH1592644.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            68730..69425
                     /gene="trmD"
                     /locus_tag="KRM55_000372"
     CDS             68730..69425
                     /gene="trmD"
                     /locus_tag="KRM55_000372"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBH1592645.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            69610..69960
                     /gene="rplS"
                     /locus_tag="KRM55_000373"
     CDS             69610..69960
                     /gene="rplS"
                     /locus_tag="KRM55_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBH1592646.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            70281..71177
                     /gene="ylqF"
                     /locus_tag="KRM55_000374"
     CDS             70281..71177
                     /gene="ylqF"
                     /locus_tag="KRM55_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBH1592647.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            71566..72858
                     /gene="brnQ"
                     /locus_tag="KRM55_000375"
     CDS             71566..72858
                     /gene="brnQ"
                     /locus_tag="KRM55_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH1592648.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT        29923 a         7247 c        13577 g        22228 t
ORIGIN      
        1 tactagaaat atgatataat ataaaaaaaa agtatatact tttatattaa aaggtgatat
       61 attatttatg aaaatcgttt aatgtataca ataatatatc tataacaaaa taataaaaga
      121 tagagtttta tttagacatt tattacaaat caaaatttat tacatattat ttataaaaaa
      181 atctaaggag gaaataataa tgaaaatatt agtattaaac tgtgggagtt cttcattaaa
      241 atatcaatta atagatatga ataatgaaga agttttatgt ataggattgg ttgaaagaat
      301 aggaatagaa ggttctatat taaaacatga aaaagcaggt agagatgata aatacgttgt
      361 tgaacaacca atgaaggacc acaaagatgc aatagcatta gttttagaag ctgttgctca
      421 tccagaattt ggtgcagtta aagaaatgaa agaaatagat gcagtaggac atagagttgt
      481 acatgctgga gaaaaatttg caacttcagt agtaataact ccagaagtag aagaagcttt
      541 aaaagaatgt atagatttag ctccacttca taatccagca aacataatgg gaatagatgc
      601 ttgtaaagct atacttccag atgtaccaat ggtaggtgta tttgatactg ctttccatca
      661 aacaatgcct aaatcttcat acttatatgg tttacctcat gagctatata ctaaatatgg
      721 ggtaagaaga tatggattcc acggaacttc tcataattat gtatctcaga gagcagcaga
      781 gatattagga aaagatataa aagatttaaa aatagtaact tgtcacttag gaaatggtgc
      841 ttctatagct gctgttgatg gtggaaaatg tgtagataca tctatgggat tcactccatt
      901 agaaggatta ataatgggaa ctagatgtgg agatatagac ccagctatat taccattctt
      961 aatgagaaaa gaaggtttag atgctgatgg attggataaa ttaatgaata aagaatctgg
     1021 agtatatgga atgactggaa tttctagtga cttcagagat atagaagatg cagctaaaaa
     1081 tggagacgaa agagctcaag ctacattaga agcgtatgtt aaaaaagtac aaaaatatat
     1141 aggcgcttat gctgctgaaa tgaatggatt ggatgttgta gtatttactg caggcgttgg
     1201 tgaaaatgga aaggctataa gagcagatat tgcttctaac atggagtttt taggaatgaa
     1261 attagataaa gaagctaatg atgttagagg aaaagaaaca gtaatatcta ctgctgattc
     1321 taaagtaaaa atgcttttaa taccaactaa tgaagaatta atgatagcta gagatacatt
     1381 aagattggta aaataattaa attaaaccta tgcctatcaa gtaaaaatac ttgacaaaca
     1441 aatgctagat ttgtataata aatttggtga tatgttgagg tgaacttaat gaaagttagc
     1501 atagaaaaaa taaatagaaa agaaactgac aaaatagact tgaatttttg tgaaaaaatt
     1561 gatactatta gttattgtga tgagatttac aaattagtat cacctgtaaa tttaaaaggg
     1621 aaagtgtcaa agactaataa aggtttgtat ctagatatag atgtcaattt tacaattgtt
     1681 gacaattgtt caagatgtct taaagaagta gaaataccac tagagtattc tatacaaggt
     1741 tttttagtaa aagaagaaga ttatgatgaa gatgagtttg aggaatttga tccttttata
     1801 ttcgatggtg aagaaatcga ccttattgat ataatagaac agacattaga ttttaatgta
     1861 cctcataaag ttctttgtag tgaaaactgt aaaggtcttt gtcaagtatg cggggcaaac
     1921 ttaaatgaag aagagtgttc ttgcagtgaa attacaaacg atgaggaata catagatcct
     1981 cgttttgcta aattaaaaga tttatttaat taaattttga ctaaggaggt ggcgtaaatg
     2041 gcagtaccaa agcgtaaaac gtctaaatca aacacaaaaa tgagaagagc agctaactca
     2101 aagatggaag caacaggatt tgtaagttgc ccacaatgtc atgagccaaa attaccacat
     2161 agagtgtgtc cagactgtgg atattataaa ggtaaagaag ttgtgtctaa gtaatagctt
     2221 ctaaaaagca tgtagagtat actctacatg ttttttttgt acatataaaa aaataagatg
     2281 atttactaga gaaaataagt ggattttatg catattaaaa aatagaaaaa taataatata
     2341 agtattgaaa atttttgtgt gttactatat actactatta gtagctggta ctaattacag
     2401 ctataaaatt tggagggaac atgaaaaaga aaagtaaagc ccaaagacaa aaagagctta
     2461 tagatatgct aaagacagat cctttttata ctgatgaaga attatcaagt ctgtttgatg
     2521 taagtataca gaccataaga ttagatagaa tgagtctaaa cataccagag ctaagagaaa
     2581 gagtcaaatc aatagcagaa actcagagtt caaaagtaaa gactttagga gtaaaggaaa
     2641 ttacaggaga aatcattgat ttatctgtag ggcgattagg tatatctatg ttagaagtta
     2701 cacaggacat gatttactct aagactaata ctttaaaaga tacgtatatt ttttctctag
     2761 cagattcatt ggcaatggct ataatagatg cacctaaggt tattatgaga gttgcaaatg
     2821 taaaaagttt taagttgata gaacaacaag ataggcttat agcaaaagca gaagtgtata
     2881 gaaatataga taaaaagcat tatgtaaaag ttgttatcaa caataaagcc caagagcaaa
     2941 tatttagagg aaagtttatc tttgaagaat tagattagga gggaaattat gaaaatagta
     3001 attgatggaa tgggtggaga taatgcacct aaatctaatg tagaaggcgc agtaaatgct
     3061 ataaaagaat atcaggttga tttaataatc acaggagata aagacttact tgaaaaggaa
     3121 ttttcaaatt atgaatttga tagaaataaa ttagagatag ttcatactac tgagattata
     3181 gaaaacgaag ataaaccagt aaaggctata agaagtaaaa aagattcatc tatggtagta
     3241 gcattaaatc ttgtaaaaga aggaaaggca gatgctataa tatcagctgg aaatacagga
     3301 gccttacttg ctggtggatt atttgttgtt ggtagaataa aaggaatcga tagaccttgc
     3361 ttatgttcag caataccaaa tgtaaagcga ggaatgacac ttatagcaga ctgtggcgca
     3421 aatgcagatt gtaaacctaa gaatctagtt gaatttgcag ctatgagtaa tatttattca
     3481 agaaaagttt taggtcttga aaatcctaag gtagcattag caaatgttgg actagaagaa
     3541 ggcaaaggca atgatttagt caaaaggtca tatgaagaaa ttaaaaaatt agatttaaat
     3601 tttataggga atgtagaagc tagagaagtt ataaatgcat acacagatat aatcatatgt
     3661 gatggattta caggtaatat attacttaaa tctgctgaag gtgtagcact ttcagttatg
     3721 agtcttataa aggaaacttt tatggccagt acaaaaagta aaataggagc attacttata
     3781 aaggatgatt taagaaaatt aaaaagtttt atagattatt ctgagtatgg gggagctcca
     3841 cttttaggtc taaatggagg agttataaaa gctcatggta gttctgatgc taaagctata
     3901 aaaaatgcta taaatcaagg aataaaattt tcaaagggaa aagtcgttga agatattaac
     3961 caatttataa gcaaatacaa tgaagaaaat aaaaataacg aagatgaata aactcgtttt
     4021 ggaggtttaa tatataatga atacaaaggc tggaatatta ggagtaggaa gttatttacc
     4081 tgagcaatca tatgataatt ttcacttcga aaaaataatg gatacatcag atgagtggat
     4141 aagtactaga actggtatta aggaaagaag atttgccaaa gagtctgaag caacttctga
     4201 cttagcatct aaagctgcct taaaagctat agaatgtgca aagttaaacg tagaggatat
     4261 agagctgatt atattagcta caattactcc tgatatgtct ttgccttcaa ctgcatgtat
     4321 agtacaagat gcaataggag cagtgaatgc tactgcattt gatatatcag cagcttgttc
     4381 tggatttgta tatggagtaa ctattgcaaa gcaatttgtg gaaacaggtt gctataaaaa
     4441 tgtgcttgta ataggagcag aaacttgttc taagttttta aattatgatg atagaacaac
     4501 agcagtattg tttggagatg gagctggagc agctgttatt ggccctgtaa atgagggtgg
     4561 aatactgtct acacatatgg gctctgatgg taaaggaaaa gattgtttaa aagtacctgc
     4621 tggaggttca agacttaagg caagtaaaga gactgtagaa gctaatctac atacaataga
     4681 aatggcaggt agtgatgtgt ttaaatttgc agttagaaag atggcagaaa cttctttaag
     4741 agctcttgaa aaagcaaatc taaatacaac tgatatagac tacttagtgc cacatcaagc
     4801 taatataaga atcatacaag cttcttctaa gagattagag cttgatatga aaaaagttta
     4861 tgtaaatata gacaaatatg gaaatatgtc tgctgcatct ataccagtag cattagatga
     4921 agcttataga gaaggtaaaa ttaaaaaggg tgataatgta gttttagttg gctttggtgg
     4981 aggtctaact tggggggctt cagttgtcaa gtggacttta tagtataaaa tatctaaaat
     5041 gatttaatta acaaaattaa acttatacac aaaataaagt tgattaataa taaaaagttt
     5101 acttttatga tttcaagtga aggagaattg tatgaataaa atttgcaaaa tattaaatat
     5161 aaaataccca gttatccaag ggggaatggc atgggtagct actgcatcat tagcaagtgc
     5221 tgtatctaat gcaggaggac ttggcataat agcagcagga aacgcaccaa aagaagctat
     5281 aaagaaagaa attgttgagt gtaaaaaatt aacagataaa ccttttggag taaatgtaat
     5341 gcttatgtcg ccatttgttg atgatataat tgatttgatt atagaagaaa aagttcaagt
     5401 tattactact ggtgctggaa atcctgcaaa gtatatggat agattaaagg aagctggaac
     5461 aaaggttatt cctgtagtac ctacaatagc tttggcacaa agaatggaaa agctaggagc
     5521 tacagcagta atagcagaag gtactgaagg tggaggacat ataggagaac ttactactat
     5581 ggtcttagtt ccacaagttg ctgatgctgt aaacatacct gtaatagctg ctggaggaat
     5641 tgtagatggt agaggaattg cagcatcatt tgcattaggt gccagtgcag ttcaagtagg
     5701 aactagattt atttgcagtg aagagtgttc tgtccattca aactataaaa acttagtact
     5761 aaaagcaaaa gatagagatg caattgtaac aggaagaagt actggtcatc cagtaagaac
     5821 attaaaaaat aaactatcaa aagaattttt aaagatggaa caaaatggag ctactcctga
     5881 agaactggat aaaaaaggta caggagcttt aagatttgca acagtagatg gagacataga
     5941 aaaaggttca tttatggcag gtcaaagtgc tgctatggta aaagaaataa caccttgtaa
     6001 ggaaattata gaggctatgg taaatcaagc aagagagatt atgccagcaa tagaactgta
     6061 aatcaggagg agcaagatgg gaaaagttgc actagtattc cctggtcaag gagctcaata
     6121 tgtaggtatg gccaaggatt tatatgaaaa taatactgtt gctaaaagtg taatagatga
     6181 ggctagtgat gccttaaata tggatttaaa aaaccttatg tttaatggaa atgaagaaga
     6241 actttctaaa actgaaaaca ctcaacctgc tatggttaca catagtgtag cagtattaaa
     6301 agcggtacaa gctcaaatag atttaaaata taatgcatgc ttaggattat ccttaggaga
     6361 gtatagtgcg ttggttgcag cagatgcaat tgactttaaa gatgctgtat gtttagttaa
     6421 aaaaagaggt aagtttatgc aggaaacagt tccagcaggt gttggagcta tggcagcaat
     6481 tttaggtttg gatagaaatg tacttgaaaa tgtggttaaa gatatacaag gaggtattgt
     6541 agaagtagca aattacaatt ctcctggaca aatagttata tctggtgaaa atgaaaagat
     6601 agaagaagca atggtaaaat gcaaagaagc aggagcaaaa agggcagtta aattaaatgt
     6661 aagtggacct tttcactcat caatgttaaa agaagctggt gtaaaattgg ccagtgaatt
     6721 agaaaaagtt aacataacta aacctaaagt tgatgtggtg gcaaatgtaa atgcagatta
     6781 ctataaaaac gaaggtaaag acctgcttat aaaacaagta agttcatctg ttctttggga
     6841 agattctata gaaagacttt taaatgatgg atatgatact tttatagaaa tgggacctgg
     6901 aaaaacttta aaagcattta ttaagaagat agcttccaat aaaaaagcaa atgtcaatat
     6961 ttataatata gatggtatag attctcttaa tgaatttgta caaaattata gaaatggaga
     7021 gatataatga taaatcttac aggacaagta gcagttgtta ctggtggctc taggggtata
     7081 ggaaaagaaa tagcaaaaaa actagcatct tttggagctg atgtagtaat caattatact
     7141 tctaaagaag atgaagcact aaaaactaaa aatgaaatag aaagtatggg ggtaaagtgt
     7201 acctctataa aatgtgatgt atctaaattt gatgaagtga atcaaatgat agattctgtt
     7261 gtaagcgaat ttggaaaaat tgatatattg gttaataatg caggcataac taaagatggt
     7321 ctgcttatga gaatgaaaga agaagatttt gatagagtta tagatataaa cttaaaaggt
     7381 gtctttaatt gtacaaaagc agttactaaa cctatgatga aaaagaagta tggaagaata
     7441 ataaatatga cttcagtagt tggaattatg ggtaatgcag ggcaaactaa ttattgtgca
     7501 tcaaaagcag gtgtaattgg atttacaaaa gcttctgcaa gagagttagc atcaagaaac
     7561 ataaatataa atgcagtagc acctggattt atagaaacag atatgactaa agtactaagt
     7621 gatgatgtaa aagaatcaac actagcaaac ataccaaaga aatcttatgg taaaccagaa
     7681 gatgtagcca atgccgtagc atttttagtt agtgacatgt caagttatat aacaggacaa
     7741 gtaataaatg tagatggtgg aatggtaatg caataataat ttaaaaagta gagaaatcta
     7801 ttaaaataaa aaattttagg aggtacacaa tgtttaataa agttgtagaa ataataatag
     7861 agcaattagg agtagaagat aaagaaataa ctatggaaac atcattaatg aaggatttag
     7921 aagcagattc attagatgca gtagaaataa taatggcact tgaagatgaa tttggtatag
     7981 aaataccaga tacagaagca gaaaacttca aatctatagg agatatagtt aagtatatag
     8041 aagctaataa atagtcgagc tttaaaaaag tggaggtatc cgatgaataa aagagtagta
     8101 ataacaggac ttggatgtgt tacgccgttg ggaacaggaa aagaagagtt ctggagtaat
     8161 ataaaatctg gagtatctgg tatagataaa ataactaatt ttgatgctag cacatatcaa
     8221 actcagatag caggagaagt taagaatttt catccagaag aatatataag taaaaaagaa
     8281 ttgaagagat tagataaatt tgctcaattt gcaatagtat ctgctaaatt agcagttgaa
     8341 gatgcaaatc ttgatttaga taaagttgat agagaacgtt ttggtgttat aataggttct
     8401 ggaataggtg gagttgaagc tatagaaact caacataaaa ttcttttgga aaaaggaaat
     8461 aaaagagtaa gttcactttt tgtacctatg atgataggaa atatggcagc tggtcaagtt
     8521 tcaatatttt taggagcaaa agggcctaac actaatgtat gtacagcttg tgcatcagga
     8581 actcattcaa taggtgatgc ttttaaggta attcaaagag gtgatgcaga catcatggta
     8641 gcagggggct ctgaagctgc tgtaacaggt cttgcttttg ctggattctg taacatgaag
     8701 gctatgtcaa ctagaaatga tgaccctaaa actgcatcaa ggccatttga taaagacaga
     8761 gatggttttg taatgggaga aggagcaggt attgttatct tagaagactt agaacatgct
     8821 ttagcaagag gcgctaaaat atatgcagaa gtagttggat atggtttaac tgctgatgca
     8881 taccatatga caactccagc tgaaaatgga gagggagcag ctaggtctat gaatatggct
     8941 ttgaaagatg gaaatgttcc attagaagaa gtagattata taaatgctca tggaacttca
     9001 acttattaca atgatttata tgaaactatg gctataaaaa ctgtatttgg agaaaaggca
     9061 tatgacttat gtgtgtcatc aacaaaatct atgactggtc acttattagg agcatcaggt
     9121 gctatagagg ctgttgtttg tgctatgagt atagaagata gttttgtgcc tccaactata
     9181 aacatacaag aagttggtga agatttagat ttagattatg ttccaaatca aggtaaagaa
     9241 aaaaatatta gatatgcact atcaaattct ttaggatttg gtgggcataa tgctacaata
     9301 gtactaaaaa aatatgtata aataaatatt aaatataaaa ctaaaaaaca agcacttgtt
     9361 ttaactgtat aaatttatat tagcttaaat ttaaagtctc ctaaattatt ttaggagact
     9421 tttttattaa gatttaagtc tagcatatgt tgtaaatcat tttgatatat tgtattatta
     9481 attattaaga ggttatttat atatgcaagt tttcattcta caatatacaa aaggaggact
     9541 aaaattttga attttagact accaaagaaa aggttaccca aaaagataat ttttatatgt
     9601 atagtactta ttagtattat tttgtttata aagtatgacc aaaatggatt gaaagaaaga
     9661 gaaattataa ataagggaaa atatatgtct gaaagccttg tggcagataa ggagtatgat
     9721 gaagcaaaaa aagtggttaa gacttctttt gaatctattc cagaaaaaaa atacaataaa
     9781 gtatataatg aagtttggga tatgttaaag actatttcat atgttccaga tggaacgaag
     9841 atagtcattg attctttaga aaagatgaga gaatcagatg tgaaattatc tgatgaatgt
     9901 agatttaata tagaaaaaag attagcatca gtgtatataa tggataataa ttattctaag
     9961 gcagtagatt taactgtaaa gtctataaag ttggctgaga aattggggaa taattatgaa
    10021 aaagcaagac tagatgttga tttggcgagc atatttttaa agataggtgg ctatgaaaca
    10081 ggagagaaat taataaagga ttcttttaaa atagatattg atgaaggtga aaaaaatgga
    10141 atggttagat tatatgctat tataaatcta gcagaaatat atgtagaaga gggcgaatat
    10201 gataaagcta ttgaaataag tagcaggata aaagattata aaaagtttgt aaatacggat
    10261 aattacaatg attttgatat aatggcctct ataatgcagt caaatgcgta tgtgggcaaa
    10321 aataatatac aaaaggcaaa gactttttta gaaaaagctg attatcttat aaaatcagat
    10381 agaacagttt atatattaga taaagatatg tactattata tggcaatggg aaacttagaa
    10441 tataaaagcg aaaattataa ttctgcaata gataattata aaaaaagttt agagatatct
    10501 actaaaagaa agttaaccca ggagaaaata aaaaatttaa ataagatatt aaatatatat
    10561 gaaaaacaag gaaatataga atctttaaat gagtatcaaa agatgttaat aaatgaatat
    10621 aaagagaaca aaagtataag agattcagag actagtttct atataattga taaagtatca
    10681 aacgaaagta agctatttga aaaaactaaa aaagaaataa aatattataa aatattattt
    10741 acagtaattt taattgctat attagggtct acttttttat acaaccgatt gaagtatttt
    10801 aaagcacaaa atttacatga tggtcttaca aatgtttata atagaaaaag ttttgatatt
    10861 atgtatgaaa agtacagaga gaaagatgat aattttgcac ttgtgatgat agatattgat
    10921 aatttcaagc tcataaatga taattatgga cataaatttg gtgacactgt tataaaggga
    10981 ataacaaata ccatttgtgt tatgttagaa caagatgata aagtctttag gtacggagga
    11041 gaagaatttt ctgtattaat aagaaataaa tctggtgatg aagtagcaga tataattgac
    11101 agtataaggg ttgcaattgc aaataaaaag tggaatgatg atgtgactgt gactataagt
    11161 gcaggtgtag ctcatgtttc agatagcaaa gatgtactag aagaagctga taaaaattta
    11221 tataaagcaa aacaacttgg tagaaataaa gtagtatata agtaattata tactatataa
    11281 ataagaggta taaatatgaa acaatcaata gctatagtaa ctgataaaat aactaaacta
    11341 tcatctttct tagaagaaaa tatacgtttg gttttaggta attatattga tataaaccac
    11401 tattatctgg aagttttaaa agagaatgat aaaatacaag gtgattttgt actagtaatg
    11461 aatgatgata gattaaacag tatgagaaag catttagtac aagatagtaa gattatagtg
    11521 ataaggagaa cacttaaaga aaatgaaata tatggattat tttcaatacc aaatggaact
    11581 gaagtattgg ttgtaaatga tacaaaagaa actaccttag aaacgataag cttattttac
    11641 aaaataggag taaaaaattt aaagtttact ccatatattg aaggaaaaat ttataaaaat
    11701 atagacatag ctataacacc tggagtaaag ggaaaagtac caagttatat aaataaagta
    11761 atcgaccttg gaaatagata tattgatata tctaccttta tagaaataat aaatggtctt
    11821 agaatagatg ttaaagaaat acgtaaaaat ttaatggcat attctgagag tttaataagt
    11881 ttagataatg gagttaaaga taattatagg caactgtttt taaaaataga agaacaagat
    11941 gttatattga atctatcaaa agatggaata atatttactt cagcagatgg tataataaac
    12001 acatttaata aagaagcttt aaaaatttta ggtataaatg aaaatccaca aggcaaaaac
    12061 atagaagata tcatttctga agatttaaat attttacttg aagacaaaga aataattgat
    12121 gaagtggtat ttacaaataa aaaatatata aatgtaaata aaaaaagtat tttttctatg
    12181 gggaataaag ctgggatata ttataactta caagaaataa cgtatataaa aaaattagaa
    12241 caaaatctta ctaataaatt aagagaacaa ggtcagatag caagatatac atttaaagat
    12301 ataaaaacta aaaataaaaa tatggtaaag tgtgtagaat tggctaaaaa aatatctaaa
    12361 tcagaccttt ctgtattaat aataggagaa agtggtactg gtaaagaatt attatcacaa
    12421 tcaattcata atgcttccaa tagaagtaat caaccgttta tagcagttaa ttgtgcagca
    12481 gttccagata gtctattaga aagtcaactg tttggatatg aaaaaggctc ttttacagga
    12541 gctttaagag aaggaaaaaa gggtctattt gaacttgcta ataatggaac tatatttctg
    12601 gatgaaattg gagatatgcc tccattgcta cagacaaagt tactaagggt attacaagaa
    12661 aagcaggtta tgcctatagg ttcccataat gttataaaca tagatgttag ggtcatagca
    12721 gcaacaaaca aaaacttact aaagatgatt agagaaggaa aatttagaga ggacctgtat
    12781 tatagactaa atgtattgcc aatagatgta ccatcattga ggaatagaaa agaagatata
    12841 ataacactta tgaatttctt tttgaaaaac aatataagac tttcgccaga agttataact
    12901 attttagaaa aatataattg gccaggaaat ataagagagt tacaaaatgt tgcttcttat
    12961 gtaagtctaa tgtgtgatag tatggttttt agagatgact taccaccata tataagggta
    13021 gaatgtgcta acaattatga agatggattt ggttatacaa gaaaagaatt tgaggaaata
    13081 ctgaggattc tatatgaaag aagagagtca tcctctggaa ttggaagagg gtttataatc
    13141 gaaaagctta tacaggaagg tattgagatt tctgaaagca aagttagaaa ggtgctatct
    13201 tatttaagtg aatgtggata catatcatct aaatctggta gaggaggaag tcaaataacc
    13261 tcagagggga taaaacttta taataatata aattaagcta agtatttgat attgaaatca
    13321 catattttga atttagatat ttaaataata ataaactttt atatttatag agattaattt
    13381 atattatgtc agaaagaata ttgtaattta taattaaata ttaataggtt tttaaaatag
    13441 gattagatag gtaataggtt aagttagaat aacccattac ctatttttat ttgtaagaaa
    13501 agtgtacata gaattagaag taaaaaatac aactaataaa actattgaaa atactagata
    13561 aataataaat aaaaataatt atagattttg gcatacatat tgctaattat agagataaga
    13621 cgacaaaata attgggaggt ttaatgatga aatacaaaac aacagggact tgtgctacag
    13681 aaattgaatt tgaagtaaaa gaaaataaag ttacaaatgt aaactttata ggtggatgtg
    13741 atggaaattt aaaagggcta aaagtattag ttgaaggcat gaatatagaa gatgtaatac
    13801 aaaagttaaa aggaatagag tgtaaaacaa agccaacatc ttgcccagac caactgtctc
    13861 tagcattgga aaattatatg aatataaagt aatacataaa acaatcgatt agttaggagt
    13921 ttaattatga aaccaataat agggatttta ggaaatttaa taataatgga aaatggtatg
    13981 tttccaggtc ttgaaaggtc atatgtaaat aatgattata taaatgcagt gctaaaaggt
    14041 ggcggtagtc cagtaataat tcctgtaaat acagataaag aagttataaa aaaacagatt
    14101 gaaatggttg atggagtctt aatatctggg ggatgggata tcaatcctca actgtatgga
    14161 gaagaaacaa gagaagaaac gacatttata tatccagaag tggatgaatt tgatttaatt
    14221 gcaataagta tagcattaga acttaaaaag cctatattag gtgtatgtag gggactacaa
    14281 attttaaatg taagtttagg aggaacttta tatcaagata ataatcttat agaaggaagt
    14341 tatataaaac atacacaatc ttctaaaaga catgtagcta ctcataaagt tgatgttaaa
    14401 gaaggaagta ttttagaggg aattttagga aaacaattac ttacaaatag ttatcatcat
    14461 caaagtgtca atcagcttgg aaaaggatta aaagccatag catactcaaa agatggtata
    14521 atagaagcta ttgagaaaga ggatgaaaat tttgtagtag gagtacagtg gcatccagaa
    14581 atgatggtag attactgtga taaaatggaa aaactattta aatattttat aaatatttgt
    14641 tcgaatttat aatatacctt ggggggattg aacatgaacg aaaagaacaa aatgggatta
    14701 ataagtatta tacttttagg tattaatgca gtagtaggag ctggagtttt tctattacca
    14761 ggagatgcaa tgaaatcatt tggtgtagca agtatatttg tatatatatt tgatatgttg
    14821 ttagttttat ctatggcatt ctgttttgct gaggttgcag gtaaattcaa taaaaatggt
    14881 gctgcctatg tatatacaaa agaagctttt ggagattttt gtggttttga agtaggtctt
    14941 atgaaatggg taataggatg tatttcttgg ggagctttaa tagtaggttt tcctacatca
    15001 ttatcagcag tatgggctcc agcaggtgaa ccacatatac aaaaaattat aattgtagct
    15061 atgatagttg ggcttacaat tataaactta ttaggtgtat ctctatcaaa aattgtacaa
    15121 aatgttataa ctgtaggtaa actaattcca ttaatactat ttataggaat aggtatattt
    15181 tttataaaag gagttaattt tacttcttca acaatggtac ctccaggagc tggagcaaca
    15241 gagtttggag cagcagcact tttaatgttt tattcattta caggatttga atctatagca
    15301 gttgcagcag aagatatgga aaatccacaa aaaaatatac caatagcaat tataagtgta
    15361 atagtaattg catcaataat atatatatta aatcaagttg tatgtgttgg tatactagga
    15421 gattcgttat ctagtacatc tacaccagtg gcagatgctg caagaatatg ctttggaaat
    15481 atgggagctg gattggttac ctttggaaca ttggtttctg ttggtggaat ttgtatgtgt
    15541 ggtgcttttg taaatccaag aagttgtgta gctttagctg atgataaaat gttaccgaga
    15601 atatttgcaa gaaaagataa aaaaggtaca ccatatgtag cgataatagc tactatgtta
    15661 atcactatac caatagctct atctggaagt tttgctgaat tagcagcaat aagtgcagtt
    15721 gctagattca tacaatacat accaacatct ttatccgtat tagtgtttag aaagaaaaga
    15781 ccagaattag taggtacttt taaaactcct tttggagcag tgattcctct aattgctgta
    15841 tgtgttggaa catggttgtt attccaagca tctatgcatc aattaattat gggattagga
    15901 gctttggcaa ttggagtacc attatacttt ataatgaagt cttataatag aaaagtctat
    15961 ggtgaaaatt taaagaaaat agtttaatta tgttataaca atttattgag ttaaaattag
    16021 acattggcag aaaattaaat acaaataagt atctacaagg ctatattaaa atattattaa
    16081 ttttttattt taatatagcc ttatattgtt atcaataaat gaaaaatatt gtaacaacag
    16141 aagaacaata gtattatgtt tatagacaaa aaacttatta ggaggtaaat ttatgccaac
    16201 aataacatta aaaaatggtg tagacgtact tattagagaa ggtgtaagag aagatgctca
    16261 aagcattata gatttttata atgaagtggg tggagaaact cattttctgt catttggaaa
    16321 ggatgaatat aaaatatctt tggaggaaca agaaaatgct atagaatcag caaaagcatc
    16381 tgataattct gttaaactga ttgcatttat agatggtgaa atagttggga ttgcaacgat
    16441 tgattctaat caaaaagcaa aaggaaagca tgttggagta ttaggaattg ttgtaaaaga
    16501 aaaatattgg ggaattggat tgggtaaaag gcttatgtta gaccttatag aatggtgtaa
    16561 atcaaatgga ataaccaaga agataactct tgtcactaat gaagaaaatt ataatgctat
    16621 aggattatac aaaaaagttg gatttgaagt agaaagcata ctaaagaaag aatgttatta
    16681 taatggtgtt tatactgatt taataggaat gtcactttta ttgggaatat aattagtgta
    16741 cattttatct cgaaaaaagt atattaagta tggtataatt aaaaaagaat ataacttaat
    16801 ataattttgg aggacgaatt atgaaaaatc tgtgtaaaat atcagatgat tatttaaaca
    16861 gcaagcttaa gtatttaaag ttattatcaa aacaatatcc aagtatatca aaagcaagta
    16921 cagaaataat aaatttagag gctatattaa atcttccaaa gggaacagag cattttataa
    16981 cagatgtaca tggtgaatat gaaccatttg tacatgtatt aaaaaatggt tctggtgtaa
    17041 taaagagaaa aatagaagaa ttgttttcaa atacaataag agacagcgaa aaaaaaatgt
    17101 tagcaactct tgtatattat cctgaacaaa agttagacct aataattaag caagaggaaa
    17161 atatagatga tttttataga ataaatattt atagacttat agaactttgt aaatatgctt
    17221 ctagcaaata tactaggtct aaagttagaa aactgttacc agaaaatttt aaatacataa
    17281 tagaagaact tttgcatgag catgttaaaa gtgaacataa agaagagtat tataaaagta
    17341 tagttgaaac aatagttgac ataggaatag ctaaggagtt tataattgct atttctacag
    17401 ttatacaaaa attggttgta gatagacttc atgtaatagg agatatttat gatagaggtc
    17461 caagaccaga tataattgtc gataagctta ttgaacatca ttgtgtagat attcaatggg
    17521 gaaatcatga tatattgtgg atgggtgcag cctcaggtga aaaaacttgt atagcaaatg
    17581 cactgaggat atcagctaga tatgcgaatt tagacattgt agaagacata tatggaataa
    17641 atctattgcc tttagccact tttgctatag aaatgtataa agatgaccct tgtaaagaat
    17701 ttattccaaa ggttaatgac caaagtgtaa caacaacaga aaagtcttta atggcaaaaa
    17761 tgcacaaagc aataagtata attcaattta agcttgaagg tgaggttatc agacgaagac
    17821 ctgaatttga aatggaacat agactcttgc ttaatatgat aaactatgat gaaggtacga
    17881 ttaatttaaa aggtaaaaca tataaattaa aagatactta tttacctaca atagacaaaa
    17941 aagacccata taaattaact atggaagaaa gaaatgttat tgataaatta gtatcttcat
    18001 ttagaggtag tgaaaaacta caaaaacatg tttcattttt gttttctaaa ggaagtatat
    18061 atttaaaggc taactcaaat ttactgattc atggatgtgt accgttaaat gaagatggaa
    18121 gctttatgtc tatgaatata atgggaaaag agtataaagg taaggctctt atggataaga
    18181 tggagtctct agcaagagaa ggatttttct ttaaagataa ggcagaagaa aaactgtatg
    18241 gcatggatat tatgtggtat ttatggactg ggaaatgttc atcattattt ggtaaagatg
    18301 atatgactac atttgaaaga tactttatag ctgaaaaaga gactcataaa gaaaataaga
    18361 acccatattt taaacttaga gaaaatgaga tggcttgtaa aagattattt gaagaatttg
    18421 atttagaact tgatgaatct catataataa atggtcatgt tcctgtggag agtaaaaatg
    18481 gagagagccc aataaaagct aatggtaaaa ttctcgttat agatggtggt ttttctaggg
    18541 cttaccaaaa aactactggt atagctggat acactttgat atacaattct agaactttgc
    18601 aattagtatc gcatgaacca tttaattctg ctgaagaagc cattgcaaat gaaagtgata
    18661 tcttatcgac aactgttgta gtagagcata aggcaaagag aaaaatggtg agagatactg
    18721 atgaaggaat aaagatacaa gaggaaatag aagatttaaa actactttta atggcttata
    18781 agaaagggct aataaaagaa atgtagatgt tatagaggca cttcatgatt gaagtgtctt
    18841 tttgttaata cttattaaat atattataaa gattaataat agtagtttat attatactta
    18901 ctaagtgaat ccaagataaa tgggttcact ttttttattt ataaacatta ttaaaaaaat
    18961 atagatgttt tggttatatt ccttgtcctt tataaataga attatataaa caaaggagga
    19021 ggacaagaga tgaataaact ttctgatgaa ataataaact ctctttctac aactataaga
    19081 gaaaaggtag aaaaagtctc aaacaataat ctgaacatag aagaaattag gttacgctca
    19141 caaaaaccat tgatactaaa tgcaaactct aaagattatt tttacaatca aaaaactatg
    19201 acacttgatt taaatcaaca aaactcatat gtagtaacaa gagaagatgt agagcaaact
    19261 tttcaaataa tatgtaaata ttcaatacat tcatttatgg atgacataaa aaaaggattc
    19321 ataactttga gaggaggtca tagagtaggg ttagttggaa aagcaatagt agaagatgga
    19381 caagtcaaaa atataaagca tatatcatct ttaaatataa gggtatcaag ggaaattatt
    19441 ggatgctcgg ataagatttt aagtcatatc ataaagggaa aaaatcagat taataatact
    19501 ttgataatat caccacctca atgtggaaaa acaactttaa taagagatat agtaagaaat
    19561 ttaagtaatg gtaatgaaga ttatggattt aaaggtttaa aagtggcttt agtagatgag
    19621 cgtaatgaga tagcaggagc ttatctaggt gttccacaaa tggatgtggg aataaggact
    19681 gatataatag aaacttgccc aaaagacttg ggtattacaa tgcttttaag gtctatgtca
    19741 ccaaatgtta ttgtgacaga tgaaattgga agtgaaaaag aaataaaggc attatacaca
    19801 gcattaaatg gaggtatagg attaataact actgtgcatg gagattcaat agaggatata
    19861 caaaatagaa aagaattaaa tagacttctg gataaagagt tatttaaaaa ggttataatt
    19921 ctttctgcaa aaagaggagc aggaacaatt gaaaaaattt atgatttaga agaaaagaga
    19981 tggtattttg caaattaaaa taattattat agctttcttg ataggaagta gttatttgat
    20041 aggtgaacaa atatacaaaa cttatactcg tagacataaa caattaaacg atttaataag
    20101 agttttagaa attttgagga tggatttatc ttttggactt tatacattag aagaaatctt
    20161 taataggata ggtggaaata aagagttttg tttttggaaa tttttctatc aaatatcaga
    20221 aggacttcac aatgaacaaa gtaaaacttt ggaaataata atatcagaaa atattgatgt
    20281 cttaagtaaa gaaacttatc taggcaataa agaaattgag gaactgaaaa atctaatact
    20341 tactttaggg aaaagcgata tagagtcaca acaaagaatg atagatttat ctatagaaaa
    20401 tttgaaaaaa caaacctatg agacaaagga agatataaac aaaaaaggcg tattgtataa
    20461 aaaattagtg acattcatag gtataggtat atgtattata ttgatttaat atggggaggt
    20521 ttattatgga aatatcattg atattaaagg ttgcaggtgt cggtattcta atatcagtat
    20581 tgaatatgat attggaaaaa acagatagaa aagattgggc aggtcttact acattagcag
    20641 gtgtaataat cgtattgggt atggtaataa cagaaataag tgacttgttt aatactgtaa
    20701 gaacaatgtt tcaactttac taaagaggag ggagtaattt ggaaataatg caattaatag
    20761 gaattgcaat catttcaact acactctgtt tagtaattaa aaaagataga ccagagatag
    20821 caaatttcat agctataata actggagtaa taatactatt gtcagttatg tttaagctaa
    20881 attttatagt agatagtata caagatttgg ctaacaaggc taacatcccg actatgtata
    20941 tatcattaat aataaaatta attgggatag catacttaat ggaatttgcg atacaacttt
    21001 gtaaagattg tggggaagga aacattgctt caaaactaga atttggaggt aaaataatag
    21061 ttatgtcaat gtctttccct atacttttgt ccattgtaga aatggtggtg aatataattc
    21121 catagatgtg tatcttggaa tgaatataag tatattagag agctttcgtt gtattgaggt
    21181 ttatagagtg aagagaggca tggttgctta tgaaaaaaag atttttacca atgattatag
    21241 gttttttatt tactttcttt tttgtaaata tctttgctat tatgatattt gctaatgaag
    21301 taccaagtag tgaagataaa gaatatggtg aaacaaaaaa tagcatagat aagtatatag
    21361 atggtcaatt agacaagcta gatataaatg agattcaaga ctatataaat aaagaaatag
    21421 ttattaatga tgttaattta aaatcatttg taaaagattt aattagtgga gaaaaaaata
    21481 tcttagattt attcaataaa gatggattga agatattgat gtttgatgaa tttaaagcaa
    21541 gtttaaaggt agtagcagta attttggtac tggctctgtt atcatctatt ttaaagagtc
    21601 tggaaaactc tttttcatca ggtgcagtaa gtcaaatagc aacatatata atatttatca
    21661 caatggtatc acttacactt attggtttta aagatgtatt acagatttgc tatgatgcaa
    21721 tagaccatac tgtaggtctt atgcaagtta taatgccaat attaataaca tttttacttt
    21781 taattggatt cccaataacg tcgactactt tgaatcctat cttcatagga ggagtaacat
    21841 ttataaatgt attttttaaa aattttctat ttgtatctat tactgttgca tttggaattt
    21901 taataataaa caatttatca aaaaatataa ggctaaagag atttttctcc tttgtaaaac
    21961 aaataaatta tgtttctatt ggagctatgt ttactgttta cttaggtctt gtatccatac
    22021 aaggactgta tgtaaccagt tttgataaat tcagtgtaaa gactgctaaa tttgctatag
    22081 gtaattttat tcctgttgta ggtggatttg tatctgactc tgtggatatt ttattatctt
    22141 catctcagct tataaaaaat atatttggag gaatagggct tatcttactt gttggaattt
    22201 gcttacttcc agtaataaaa attttatcag taatagtagt gtacaaatta gcagcaataa
    22261 ttgtagagcc tgttggagag gatggaatat ctaatttttt aaatgaagtg gcaaatttaa
    22321 tgataataat gctagcatca gtaattgcta taacagtaat gttctttgta actgtagcta
    22381 tcttgacctc gataagtgtc gtaagtcaag ggtaatttat atatcagtga aaaataatta
    22441 catttaatct aatgttttta gagaggagga tgctatgtta gagggcataa aggcatggat
    22501 agttagtgtt ttgataggag catttatagt aaatatagta gatatgattt taccaagttc
    22561 taagataaaa ccttatgtca acctagtttt aaactttatg tttgtattta ttgtaataac
    22621 tccagtagta ggattttttt caaaagatat gagtttagaa gatagaatat taaaatctat
    22681 gggaaactac aacaagcagt atgtagatag tacaaatgct ttggcaaaag agactggaaa
    22741 taatagtcta tccaagggat atgaggatgg gttaaaagaa gtacttaaat taaaacttga
    22801 tgaatatggt tatgatttag aagatataga gcttaatggg gcaaatataa ataatataaa
    22861 aataaaagaa aagaataata gtgcaaaaag taataacagt tccaatgaag aaaataaaaa
    22921 taatagtact aaaagagagg aagaaaacat aaactctaat gacaaagaaa attctaaaca
    22981 agtcttcaaa aaaggtacag agtatgggtt gaacctaaat gaagaaaaat taaaaaacga
    23041 cttaataaag gtgctggatg tttctataga agatatacaa attgataaat aggagttggg
    23101 agaatgttga aaaacttaaa tgacaaagat aagagaaagg tatattcact aataactata
    23161 gcaggaatat gtgtggtttc attagtatta ttatcttgtt ttcctagtag caaaagcgat
    23221 aaacaagttg gaaaaacaga gactaataaa aatgctgaaa agcaagtcac taaagaacaa
    23281 gaaaaagatg atttagagtc aaaattaaca gcaatactat ctaaaattga tggtgcagga
    23341 gacgttgatg taatggttac atttgaatca agtgaagaaa tacaacctgc ttttaattca
    23401 aataatacaa cagaaacaac agaggaaaaa gatgcacaag gtggagaaag aacagttacg
    23461 acttctagtg aaaataaaac aatgataact tcaaattcaa gtgaccctgt agttataaaa
    23521 actacagagc caaagataaa gggagtgata gtggtagcaa gtggagcaag tgacccaagt
    23581 gttaaagaga cactttatag tgcagtacaa acatcattac aagtagctgg tcatcaagta
    23641 gaaatatatt ctaaataaat acatataacc ggggggataa atgaatgaag tttaattata
    23701 agggaagagg atttgtaata ataactttaa ctgcaatgtt agtggtagta ggaacagtga
    23761 attatcaact aagtaagaaa tctttattag aaacatcaaa agagtttaag gcatatgaag
    23821 aagcacagtt gcaaaaaaat actgatgaga gtgatagtag taagacagag gattctagta
    23881 atatagataa acaagatggt aaggaaagtg ctgatattga tatagttgat agcaaagcta
    23941 gtaaagtaaa agaaaaggca actgagacaa gtaaggaaat aaaagctcaa ttatcatcag
    24001 agaaaaatat gaaaaaggca tcttatattt tagatatgaa aatgaataga gaaaaacaaa
    24061 gaaatgagtt agttcaagat ttaaatgaaa tgataaataa tccatctaca acagaagaat
    24121 ctagaaaaga agcttctaat atgaaattaa atatagttaa aattcaagaa aaagaacttc
    24181 aaatagaaaa ccttttgagt acaaaagggt atgaagaagc gttagtttat ataagcgata
    24241 acaaagttaa tgtagttgta aatgaagcta aattagaaaa gaaagatgca gcaaaaatat
    24301 ttgatttagt tgcagaacaa gccaatgtga agtatgaaaa tattaaactt acaaataata
    24361 atagtaataa gtaaagtata aacctcagaa ttaactgagg ttattttctt gcaaagtaga
    24421 cttgtatttg gtattattat acttataaaa atagttcctt aaaatcagga ggtaagtttt
    24481 aatatggaag ataataaatt tggacaagta aaaatatcta atgatgtaat agctacaata
    24541 gctggtttag cagcattaga agttgaaggc atagaaacta cagcaacatt aacagataag
    24601 ttgttaaaaa ataatggagt aaaaatacaa atcgaagaag aggatgttaa tttagatgta
    24661 atggttacga taaagtatgg aatgtcaata ccagatacag cttttaaagt tcaagaaaat
    24721 gtaaaaaata ctgttgagac aatgacagga ctgaaggttt ctcaagtaaa tatacacatt
    24781 caaggaatca gctttaagaa ggataaagtt gataaagaag aagcaaaagc aactaagaaa
    24841 aattaatatt agccctctga aaagtcagag ggttttttgc tggtaattga ttttatatgg
    24901 ataattaaac ttaaaggaga attttgattg atgaaaaaag atagggcaca aaagagtaca
    24961 acaagagaat atataatgaa acttatatac caaataaata ttaataaaga agattttgaa
    25021 actttagaag ataaagtaga taatttttta aaagataatt cagaacatat tataaataga
    25081 tataaagaac ttgcacttca atactcaaaa aatacaaatt taaagttaga agatactgaa
    25141 attgaagatg ttatagacaa aaaatatata aatacagtat gcaaagcatt gaaagaaaat
    25201 catgacaaaa tagatgagtt aataaataag catgctaaaa actggacagt agatagaatg
    25261 ccaaaggtag atgtttctat acttagattg tctgtgtgtg aaatacttta tttagacact
    25321 cctaataaag tatcaataaa tgaagcagta gaacttgcaa aaatatattg tgatgataag
    25381 tctcctaaat ttataaatgg tatattggga agtgttgttg atgaaattgg gaaataatat
    25441 aataattgga attgatacta gctgctatac tacttctata gcagctatct ctttagataa
    25501 gaaagttata ttcaatgaaa aaataatgtt agaagtaagg gataattcaa aaggtttaag
    25561 gcaaagtgaa gctgtatttc aacatatcaa taatttaggg attcttagtg ataggataaa
    25621 atcttttaaa gataagttta atgtagaagg agtttgctca tcaaaaaaac cgagacctgt
    25681 tgaaaactca tatatgcctg tattcaatgt aggtcataat tttggaaaat tattgtctag
    25741 tatatatggt tgtaggtttt atgagactac tcatcaagag aatcatattg aagcaagttt
    25801 attaaatagt aaattaaaaa ataataataa atttatttct gttcatatgt ctggtggtac
    25861 tacagagata cttttaacaa gcaaacaaga tagtcatcac aatgtatgtg atactaattt
    25921 aggtaaaatt gccaaaataa gtattaaaaa agatgataaa agtaagttat acaataattt
    25981 tggatataat atagatataa ttggaggaag taaagatatt agctttggtc aacttataga
    26041 tagagtagga attaagcttg gatataaatt tccttcagga aagtatttgg atgaaaatgc
    26101 tttaaattgt aatcttaaaa tagaaagtgg tctgaaaact tctgtaagag atgggtatat
    26161 gaatttatca ggattagaaa atcaggtaaa taagattata aatgataatg gatataatac
    26221 taatcaaaaa gaatatatat ctaaattggt attagattca gtagttagaa atatgtttaa
    26281 atctttagtg tatttatgtg aaacttataa tgtaaatgaa gtagtatttg ctggtggagt
    26341 ttctgcaagt aagtatattc ttagagaatt aagcgtgaag ttaagaaaaa agcatataga
    26401 agcttatttt acagaaccac aatattcaac tgataatgct gtcgggtgtg ctataatagg
    26461 attgaataac tttttaggag aaagagtatg aaactaagag ctttagatat aagtgaagca
    26521 aactcatata ttaaaagaat tttaataaac gacccaatac tttctaatct taaagttaaa
    26581 ggagaaattt ctaattttaa ggttcatagt agtgggaatg tatatttatc acttaaagat
    26641 gaaacatcaa agttaaactg tgtaattttt aaaagtaatt ttaatcgcaa tttaaaatta
    26701 gataatggtg taaaaattat agctaatgga tatatatcag tctatgaaag agatggtgcg
    26761 tatcaattat acattaatga aattgaaata gagggaatag gaaatttaca catagagttt
    26821 aatagattaa aggaaaaact taataaagaa ggattatttg accctaaata caagatacct
    26881 atacctaaaa tgccaaactc aattggcgtt ataacatctc caacaggtgc tgttataaga
    26941 gatataataa atgtaataaa aagaagatat ccgaaagtta atataaagct ttatccagta
    27001 acggttcaag gagataaatc agctgaagaa atctgtgaag caattagatt tttcaatcat
    27061 atgaagaatg ttgatacact tatagttggt agaggtgggg gttcgataga agaactttgg
    27121 tcttttaatg atgaaatggt agcaagagag gtttttaatt ctcaaattcc gataatatca
    27181 gcagttgggc atgaaacgga ttttactatt tgtgactttg tgtctgatat gagagcccca
    27241 acgccatcag cagcagctga gattgctact ccatcattgg atgatataaa ctataaactt
    27301 ggaaacataa aaagtaggat gagtaagtct cttacaaatc aaatagagct agaccaatat
    27361 aggttagaaa cagtatttaa taagataaat aactatttag attcgtacac aataaaagat
    27421 aaagttatac aattagacaa aatatatgat aaaataattt ttggaataga aaataattta
    27481 aaattagaag atgaaaaatt agtaaaaatt ggagcattac tccataattt aagtccatta
    27541 gctactatgg atagaggtta tagtataact caaaaaaatg gaaaagtaat aaatagtata
    27601 aaaggattaa aaataaagga tagtatagat atagtattaa aagatggaaa tttagaatgt
    27661 atgatagata aaattgaaaa taaagaggga tagtatgaat ttaacctacg aagaagctta
    27721 taaaagatta gaaagtattt taagtgaatt agaatctaaa aatgctagct tggatgaatc
    27781 tttaagccta tatgaagaag gtataagcct ttataaacat tgtaataagc ttttagatga
    27841 tgctaaattg aaaataagta aatttaatca attgggaata gaagaagact ttaaaataga
    27901 ggaggaataa aattggaatt taaacaatgt ctaaaagaaa aagcaagttt tgtagaaaaa
    27961 gtacttaaag aatatatgcc taaagaagaa gggtatcaaa aaactgttat tgaagctatg
    28021 aactatagct taagtgctgg aggtaaaaga ttaagaccaa tacttacatt ggaggcttgt
    28081 aaaatagttg gaggtaatga agatgaagct attccttttg ctattgcaat tgaaatgata
    28141 catacatatt cactaataca tgatgatttg ccagctcttg acaatgatga tttaagaaga
    28201 ggaagaccaa caaatcataa agtatatgga gaagctatgg ggattttagc aggagatgct
    28261 ttgttaaact atgcttttga agtaatgctt gcaggctcaa tcaataaaga aaatccagaa
    28321 aagtatctaa aagctataaa tgaaattgcc aaaggtgctg gtatatatgg aatgataggt
    28381 ggtcaagtag tagatgtaga aagcgaaaat aaacaaattg aaaaagaaaa attagattat
    28441 atacatatga ataaaactgc tgcaatgatg gtaggctgta tgagagcagg agctactata
    28501 ggtggagcaa attctgaaca aatggaagaa ataactaaat atgcaaaaaa tatcggatta
    28561 tcattccaga tagtagatga tatactagac atagtaggag atgaagctaa gttaggtaaa
    28621 aaggttggaa gtgatataga aaatcataag tcaacatacc catctctttt aggtttagat
    28681 aaatctaaag aaattgcaca taatttgatt gatgaagcaa agaaaagtat agaaaaatta
    28741 tctgatgatg tagatttttt aaagggattg gctgaatata taatagatag agaatactaa
    28801 aatatacagc taaaatcgag gagggaaaaa tggatttttt ttcggagatt tttaacaatg
    28861 gggctttggg aataagtctg attgcttgtt tcttagcaca atttataaaa atatttactg
    28921 gtaaggaaaa aagaattgag ttatcaagaa tacttatttc aggaggtatg cctagttccc
    28981 atagttcttt tgttacaagt ttagctacag tggtaggtat tgaaaaaggg tttaattcta
    29041 ctgattttgc tataattacc gtgcttgcct taattataat gtatgatgca gcaggtgtta
    29101 gacgggctgt tggtaaacaa gctactatat taaatcaaat ggtggcagat atacagcatg
    29161 gaaagcatat agagcagaag aaattaaaag aattaatagg tcatacacca ctagaagttt
    29221 ggtttggagc tttacttgga atagtaacag ctttaatatt gatgtaaatt gaaaatttac
    29281 agaataaagg tgaggataat atgtataaat atttagataa agtaaattct ccaaaggata
    29341 taaaaaatat gagtatagaa gaaatggatt tacttgcaaa ggatataaga aagttcttag
    29401 taaaatctgt ttcaaagaca ggaggacact tagcttctaa tctaggagtg gttgagttaa
    29461 cattagcact tcataaagta tttgatagcc ctaaagataa gattgtatgg gatgtagggc
    29521 atcaatctta tgttcataaa atagttactg gaagaaaaga ttgttttgta tctttgagac
    29581 agtttaatgg actaagtggt tttccaaagg agaatgaaag tcctcatgat atttttgata
    29641 caggacatag cagtacatct atttctatag ctacaggtat tgcctgtgct agggatataa
    29701 aaaaagaaaa ctatagtgtg atatctgtga taggagatgg ttctataaca ggaggtatgg
    29761 cacttgaagc tttaaatcaa ttaggatata tagataccaa tatgatagta atccttaatg
    29821 ataatgagat gtccatagat aaaaatgttg gaggaatgtc taaatatctg tcaagtatta
    29881 taagaaactc aacagttgag aaaatgacag atgaagttga taaaatttta aatgttacac
    29941 aaacaggtga aattttatct aagactgcac atagatttaa agataaacta atgtatagct
    30001 tttctcctca ggactgttca ttttttgatt cattaggtat aagatattat ggacctatag
    30061 atggccataa tactaaagaa ctaatagata tattgagaaa agctaaacac aaaaaagggc
    30121 ctgttctttt acatgtaatt acgaaaaaag gaaaagggta cagatttgca gaagaacaac
    30181 ctgataaata tcatggagta tcaaagtttg atataaagac aggtgttaca tctgcaaaag
    30241 ttaagtctat gtcaattagt gttggagaaa aacttgttga tatggctaat agtaatgaaa
    30301 atatagtagc aataacagct gcaatgccat ctggtacagg gctaaacctg tttgaaagtg
    30361 catatccaaa aagatattat gatgttggta tagctgaaca acatgcaaca ggatttgcag
    30421 caggtcttgc aaaaaatggt atgaaacctt actttgctgt gtactcatca tttttgcaaa
    30481 gggcatatga ccaagttatt catgatgtat gcataacaaa aaagccagtt acttttctta
    30541 tagatagagc tggattagtt ggaaatgatg gagaaactca tcatggtatg tttgatttaa
    30601 gttacttaaa ttctattcca aatattgtag taatggctcc aaaagacaca agagagatgg
    30661 agcttatgat ggatttgtca ttaaaattag attgtccact agcaattaga tacccaagag
    30721 gaagtagtta ttacctagat aagggagagt atggagagat tgtactgggt aaatatgagg
    30781 tattagatga gggtcaagat acagtcatac tttgtattgg aagtatggta aaacatgctt
    30841 tagaggctaa agaaatatta tcaagagaag gaataaatcc gacaatagtt aatgctagat
    30901 tcttaaagcc aattgatgaa ggtatgttaa aagcattatt aaaaaatcat aaaaatgtag
    30961 ttactataga ggataatatt gtaactggag gatttggaag tagaataaat aagtttatta
    31021 tagataatga atataacgta aatatactta atatagcaat accagaagaa tttgtaaaac
    31081 atggcaatat agatgaatta tatgactttg taggattatc gccaaaaagt attgctgata
    31141 agataaggaa attagttatt gagtaaaaat ctaatgtaga tattgtaaat taaaatttat
    31201 ataaaatata gaatttatca attagaataa atatcaagtg tgttacttca agctacttta
    31261 gttatcatta aagtagtttt taacagaaag gtaattgtat gaaaaaaaga atagatttat
    31321 tattagtaga acaagggtac tttgaaagta gagaaagagc caaaaaagca ataatggctg
    31381 gattggtttt tgttgataat caaaggtgtg ataaggctgg tacagaagta aaagaagatt
    31441 gtagtataga agtaaaagga aatccaatac catatgtcag tagaggtggt ttaaaacttg
    31501 aaaaagcaat gaaaaacttt gatttgacta ttgatggaaa ggtatgtatg gatatagggg
    31561 catccacagg tggttttaca gattgtatgc tcaaaaatgg agcaataaaa gtattttcta
    31621 tagatgttgg ttatggtcaa cttgcatgga aattgagaca agatgatagg gttgtgtgta
    31681 tggaaagaac caatataaga aatgtgacaa tagaagatac aaagcagttt gctgattttg
    31741 cgtcaattga tgtgtctttt atatcgttaa agttagtact tccaaaggca aaggagttag
    31801 tacgtcatga tggggaagtt gtcgctttaa ttaaacctca atttgaagca ggaagagaaa
    31861 aagtaggtaa aaaaggagta gttagagaaa aatctacaca tatagaagtt ataaaaatga
    31921 tttctgattt ctcagtcgaa aatggatttg agattttagg gttagatttt tctcctatta
    31981 aaggtcctga aggtaatata gaatatctaa ttcatttgag aaatggaaat gaaggatatg
    32041 aatttgatgg tgagacatac aataacaaaa tagtagaagt tgttgaagct tctcataatt
    32101 tagacaaata ggttaaaagg gggcttagat ttgatcctcg aattatatat gaaaaattgt
    32161 gccttagttg aagaactaag gttgaatatt gataaaaacc taaatatact tacaggtgaa
    32221 actggttcag gaaaatctat aataatagat gcacttggac tttgtttagg tgataaatat
    32281 gataggtctt ttttaagaaa aggaacagat aagggacttg ttgaggctgt atttttttca
    32341 gacaatagat atcttaaaaa aatattagaa gaaaatgata taagtatgga agatgataat
    32401 ttattggtaa taactaggtt gatatactca gatggtaaga gtactgctag agtaaatgga
    32461 aggactgtta aagtgtctct tcttaaagaa attgcatcta cacttataga tatacatggt
    32521 caacatcaaa atcaagcttt gtttaataaa gatactcatt taaaatttct agaccttttt
    32581 ggagaaaatg aattggaaga gtttaaaatt gcttataaaa atgtgtacca taagtatagt
    32641 gaagtaaaaa aagctttaaa ttgcttgaca gaaaataaag atgagatgca aattcaacga
    32701 gaaatagatt tattaagatt tcaaataaat gaaattgaag ctgcaaatct aaataagaat
    32761 gaatatgaag atttattaaa acaaagagaa gtttatagaa atagtgaaaa gatatataat
    32821 aatctaaatt cgagttatag caagttacat aatggtgagt ataatgttat tgacctaata
    32881 ggtcttgcat ctaaggaact taatgacata tctaaatatg acagtgtttt aagtgaatat
    32941 agtgatactg tagaaagaat catgtatgag ttacaagaca tatctggtga gataagaaat
    33001 tacaaagata atatagactt tgaaccttat gagctagagc agattgagct tagaatcgac
    33061 gagattaata acttaagaag aaaatatgga gacagtatag atgatatatt tgagtattat
    33121 ggaaaaatta aagatagatt agatgaaata ttaaacagag atgaaagagt tgaacagtta
    33181 agaagcaaac tgatgaatat agaagaagat ttaaaaataa aagccagtaa attgactaaa
    33241 gcaagaatag aagtagcaac tactttagaa aaaatacttc ttgatgaatt aaaaagctta
    33301 aatatgaaaa atgtaatgtt caaggttaat tttgaaaaag gtccatttac tttagatgga
    33361 gtagatgata ttgaatttat gatatctttt aacttaggag aagatattaa gcctatatat
    33421 aaagttgcat caggtggtga gatgtccaga tttatgttag cgtttaaaac catattggct
    33481 gatatagatg atattgatac attagtgttt gacgagatag atactggaat aagtgggata
    33541 gcagcacaga tagttggtga gaaattgagt gatatagcaa agaaaaaaca gataatatgt
    33601 ataactcatt tacctcaaat tgctgcaaat gcagacactc attattgtat agagaaagat
    33661 acttcaaata ataggacgtt taccaatgtt agtaagttaa atgaatctca acgaaaaaat
    33721 gaaattgcca gacttatagc aggtaacaat ataacagaaa aaactattga acatgcaagt
    33781 gaaattattg agttggctaa aaaatgttag tgaaaaacaa gcattttaat aggtgtaaag
    33841 aatttttata gaaatgcttt acatctattt tttatgatga aattatttta aaatatctag
    33901 tgcctatatt gaagaaaagt agatttaaaa atagaagaaa atttgtataa atttgtaact
    33961 ttgaaatttc taaatgctta agtataatat tatttattaa ggtagtagtg agggggacat
    34021 aaaatgaata aaaaagatac tatgcactta atttttacaa ttgtaatttt tattttatta
    34081 tggtatattg tggtaacggt aagtgagatt aataaaaata ttgaaagttg tagcaataaa
    34141 ttagattatt tgtcacaaga gattatgagt actaaatcgg atattagtaa tactataaat
    34201 gaagaaatgt caaaaagtta tataacaaag agtattgact taaaagtaaa aaaaatcgag
    34261 aaaaaagagt gtgttattga tgtagatgtt caattaagta aacttggaaa aaatggaaaa
    34321 gtatttttta tgtataaaga agatagtgat aaatggaatg aaactgagat gacaaaacat
    34381 ggagaattat catatgcatg tgaaataaag ataaatacag gaagtgaata tgactataaa
    34441 gtagttacaa gtggagctat atctgaaagt tctgatgtgc aaaaattgac taaatctgat
    34501 tatatgcctg aacaacccat atttaattct gggataagag ataatagaga atactttatt
    34561 gaaatagtag aaaatagtaa tcttttcaat catgagagtg aaaagtcaaa aaataaagtt
    34621 tatgataata ttagattaga aaaagtagat attattgtaa atgaaggaaa aaaagacact
    34681 atatacaaag ccaaattagc tgaaggctta gatgatggca aaactaataa ttcaaataga
    34741 aatcaagtga attatgaagt aagttttcct aaaagggata ttgatggcat aatttatatt
    34801 aaagctaaac ttacatacaa taatggagta gaatatacaa aggatataac tgaagatata
    34861 actatgggat tacaagattt agaaaaataa atacatattt aaataaatat tcaaatagat
    34921 ttgttcaata aaatagagta taaataaaac tgtagtagtt ttacttatac tctattaaaa
    34981 aattataatt ttaattccat atatctagcc ccttcaattg gattataagt ataaggttct
    35041 atatcataaa aaccaaactt ttcatataat ccttgtgcac ttttcatgct tggaagagta
    35101 tctaatctca tgtgtgtata tccaaatttt ttagcttctt caatgatttc ttccaatagt
    35161 atttttccta tttttaatcc tctaaattga tttcttacat ataatctttt taattcacat
    35221 attttacctt caagtttttt taaagcaaca caacctgcca aattttcatc aacaaatgct
    35281 aatatcaatg agcctgaagg ttttttatat tttcctggaa gtgtttttaa ttcattatta
    35341 aagtcttgaa aacataagtc tatatttaga gaatttgaat attcagtaaa tagaagtttt
    35401 acgttttcaa ggttttctaa atctttttct tcaacaaatt gtaaagttat attttgagcc
    35461 attttatccg ccattatata aacatgttta tataatgact tcacctcctt gatatatgta
    35521 tatttttctt aatatcaatt agattttaat accattactt tttcaccacc atagtcaagc
    35581 tctccattaa actcaaatcc aaaatcttta taaagcttaa tagccatttt attgtcttcg
    35641 aatatactaa gatatagttc atcacagtta tattcatttt taagatgatt tacaagaaaa
    35701 tctaatgatg cttttccata tcctttacct tgatattttg aatcaatcat aaatctatca
    35761 agccaaactc tatcatcttc taaacgacca tacatagcaa atcctattaa agaattttca
    35821 tcatatattc caacaggtac ccaagctgtt ataaatttag attcagcaat agaaagtgca
    35881 ttgctttcta tataatctaa ctgactttta tctacagaca aactaactaa atcatgccaa
    35941 ttatttatgt ctgcaattct tacatttaat ttcaagatat taccgccctt caaacttttt
    36001 gttacaatct aatactatca tattatgtat taaaaatcac ttattaagat tttaaataaa
    36061 ctttttaaat gaataaattc tcaggaaaaa ggaattataa atacataata atacagcata
    36121 ggagtagatg gatatatgaa caaaataaat aaaaatttca aaaatatttg gataatatta
    36181 ggagctgtat cgatttttac catggttata atttttaata aaaattgtaa tgttaataaa
    36241 gagactcaaa tagaagcttt tacaattaag aatcatgata aaaaatttgt atatcctatg
    36301 ggaaatataa ttggagtaaa agcaaataca gatggtgtat tggtcttagg atatgaggaa
    36361 gaggatgtag actatattgg aggcatacaa atcggtgata atatagtaaa aatagataat
    36421 aaaaggataa aaaatagtca agatgtatca gagattttga ataagattaa aaaaagtaaa
    36481 gttgaagtga cttttgagag aaaaaataag tataaaacag aagtaataga gactaaaaaa
    36541 gaaaatggca agtataaact tggattatgg gtaagagata aaatatctgg aattggaact
    36601 atgacttttt acgaccctag tatggaaaag ttcaaagcaa tcggtcatgc cataaaagat
    36661 tcggatacta atgaactatt aaagataaag caaggatata tatataagcc agaacaatta
    36721 aaaatagtaa aagctagtaa tgaaaaagta ggtaaaataa aaggagattt taatgacagc
    36781 aatttaatgg gtaatttctc aaataattca gagttaggca taagtggtaa tattacagaa
    36841 aaccataata aagagtttaa tgtagcaaat aaagaaaagc aattaataga agttggaaga
    36901 ccgcaagatg taaaaatagg agatgcagta attctttttg aggataaaaa caaaaatata
    36961 acaagctatg atataaaaat agaaagtata gtatatgata aaggaaatta tagagatatg
    37021 gtaataaaag tagtagatga caagttattg gaatacacag gaggtatcgt acaggggatg
    37081 agtggagctc caataataca aaataataaa attattggtg caataactca tgtttttaga
    37141 gataatccga aaaaaggata tggtattttt atagatgaaa tgataaaatt gtaggtgagg
    37201 cattaaaaaa ttttattatt ttatcaatta tctaggagga atataatttt ggagtgtcga
    37261 atatgcttta gagtagataa ttaggaagca attgtgtaaa aagtttagtt ttctgtaata
    37321 agaagatgtt ttttaatggg gggattttta gtggaaaaaa tcaaaatagt tttagcagat
    37381 gacaataagg atttttgtca ggtattaaaa gagtatttgt ctaatgaaga tgatatcgat
    37441 atattaggca tagctaagga tggaattgaa gcattagact tagtaaaaaa gacacaaccg
    37501 gacttattaa tactagatgt aataatgcca catctagatg gattaggtgt aattgaaaaa
    37561 ttgaatacta tggatatacc taaaatgcca aaaataatag tactatcagc agtaggtcaa
    37621 gataagataa ctcaaagcgc aataaatcta ggagcagatt actacatagt aaagccattt
    37681 gattttgttg tgtttataaa cagaattaga gagctagttt ctaatagagt tacacaagtt
    37741 gagccaaaac ctagaccagt tcaagagact caaatgacta gaagtgattt tgttaagaat
    37801 gtaggaaata tagagacaga aatcacaaat ataatacatg aaataggagt accagctcat
    37861 ataaaaggat atttatattt aagagaagca ataaaaatgg ttattgataa tgttgagctt
    37921 ttaggtgcag taacaaaaga gttatatcca agtatagcta aaaaattcaa tacaacacca
    37981 agtagagttg aaagagcaat aagacatgca atagaggttg catggagtag aggaaaagtt
    38041 gacacaataa atcaattatt tggatatacg gtacacaata ctaaaggaaa accaactaat
    38101 tcagaattta tagcaatgat tgctgataaa ttaagactag aacatagtat ggttaaataa
    38161 acaagacata aaaagtaagg ctttttaatt aaggcattgg ctataaatgc gtattacaag
    38221 cagcgaaacg gtataaccac tagggttata ccgtttcgct attttaataa atataaaaat
    38281 tttctttatt atttgcttac tatatcaata taataacttt attatactat ggatatagta
    38341 tgtgtcttta caagttgtaa actgacagtg gtttattttt taatataaat attgactttg
    38401 atgcaggtaa actttgtatt tttaagcgta ttatggaata tgttaaataa aaaaatgatg
    38461 aaatatagta ttgtaaatgc caaagatgca aaacaaactt aaaacattta ttttattgtt
    38521 aagtaatgct ataatataat gtgattttaa taatgatagt ggaggtttaa atatgagagt
    38581 cgaggcccct ataaaagtag atcgaaaaac caaaaaactt gctaaaagag ttgaaagtgg
    38641 ggaaatagca gttataaatc atatagacat agatgaagtt gctgcaaact ctttagtaga
    38701 agctaaaata aaacttgtca taaatgcggc tccttctata agtggtaggt atcccaataa
    38761 aggtccaggg atattaactg aaaataatat actaataatt gataatgttg gagaagagtt
    38821 atttgaagaa ttaaaagaag gagaaactat agaagttgta gatggaaaga tatatagaaa
    38881 aggaaaattt ttaggtgcag gagaagtttt agacaagtat gaggtttcac accaaataaa
    38941 ggctgcctat gagaatttag ctgtagaatt ggatagattt atagataata ctatagatta
    39001 tgctaaaaaa gaaaaaggat ttatacttgg agaagtagaa attccaaaag tgaaaactaa
    39061 ttatgctaat aaacatgtat tgatagttgt aagaggtcag gactacaaag aagatttaag
    39121 tactatgctt tcttatatag aagaggtaaa gccagtattg gttggtgttg atggaggagc
    39181 agacgcttta attgagtttg gatatactcc agatgtgatt gtaggtgata tggatagtgt
    39241 aagtgatgaa gctttaaaaa aggctagtga aatagtagta catgcttata cagatggaag
    39301 agcaccaggt cttaaaaggg ttgaggaatt aggcttagat gcagttgtat ttcctgcacc
    39361 aggaactagt gaagatatag ctatgcttat cgcttatgag tataaggctg agttaatagt
    39421 agcagttggt acacattcaa atatgattga ttttcttgaa aaaggaagaa aaggtatggc
    39481 aagtactttt ttagttagac taaaaatagg ttcaaagctt atagatgcta aaggcgttaa
    39541 tttgttatac agaagtaaat taaaaataaa gtacatatgg gcattaatag caacagcatt
    39601 atttcctgtg ttggtagttg catcattgtc accaggagtt caacagttca tacaactaat
    39661 gcaattaaag tttagagtat tattacagat gtaaatttta ggaggataaa tatgcatatt
    39721 aatatgaaat attatatagt cactataggg gctatattta tagctttggg tataggcatg
    39781 ttagtaggat ttaatttaaa taataatcaa caattaagtg aacaacaagc aaacataata
    39841 aatgatttgg atgataagtt tgatatctta aaagaaaaaa atgataaact tgacagtgac
    39901 ttagcaagtg taaatagaga ttatgaagag gcagttaatt ttataaataa aaatgtagat
    39961 aagattttag ctggttcgct gaatggtaaa agtataggaa taatatctgc taatgaaaat
    40021 gacgattata caaaaaatat agaagacata ataaataaat ctaatggaag cattgcattt
    40081 aatataatat taaaagaaaa cataacaaat ccagaaaagt taaaggaaat gtcaactaaa
    40141 ctaggtacag atgtaaaaaa tgcaaatgat gcagttaatt atataattga cactcttaaa
    40201 aaggaagatg caagtgacat tttaacatat cttcaagaac tagatgtaat aaagtttaat
    40261 tttattggag atacatatct aaaatatgat tccgttgtaa tagctggtgg aaatgatgca
    40321 aaagacagta caaaacagtt tgaaaaaata gaaaaatttg tagtttcaaa acttaaatca
    40381 gagaataaat atttagtaga agttcaaaat acaggagtta aaacttctta tgtagaacta
    40441 tattctaaaa acaaagttgc aactatagac aatattgatg aaggtatagg aagtatatct
    40501 ctagctattc ttctacaaca aggtaatata gttggtaatt ttggtagatt ggatactgca
    40561 acttcattgt tgccatctat taaatagaaa taattttaag gagagaaaaa atggattctt
    40621 atataagtat aataatacca gcttataatg aagaaagtag aataaaatat acattagaaa
    40681 gcatattgga cattaagcaa ataaatgaaa taatagttgt ggatgatggt tcaattgaca
    40741 atactgctaa ggttgtatct gagctagaaa atgaaaagat taaatttttt aagttagata
    40801 aaaatagagg taaaggatat gctttaaatt atggtatcaa attagcaatg aaaaatgcag
    40861 atattatagg ttttctggat ggagatttag gaagttctgc taaagaagtt gaaaaattaa
    40921 tagtacctat attaaatggt gaggcggatg ttacaatagc caagtttcct cctgcaaaga
    40981 gaaaaggagg tttgggattt gtaaaaggtt tagctaaaaa ttctgtgttt gagatgactg
    41041 gtgttgagtt agatgcaact ttatcaggtc aaagaatatt taaaagagaa gttttagaaa
    41101 agtttgatga aatacctttt ggatatggag tagaagttgg aatgaccatt gatatattaa
    41161 agtatggatt taaaattaaa gaagtattag taaatatgac tcataatgaa acaggaagaa
    41221 atttaaaagg ttttattcat agagggaaac agtattatca cataaaaaag gttttaggac
    41281 aaaaaaagaa agaatggagg taatatctta gtgaaagatt atatacttta taccatttta
    41341 ttattaactg gattatttgg aacctatgct gtaattccac tatttaaaaa tttattgata
    41401 aatggaaatg tacttagacc aaactataaa aaagatatga taccagtaag tatgggaatt
    41461 gtatttttgc ctatgattgt aatcaatgga ataatacttg ctttctttac tacagaattt
    41521 aaggatttag cgtatatatt tatgtttatg tttggtatga tatccatgtt ttttgcaggg
    41581 atactagatg atgtcattgg aaatagagat gtaagtggtt taaaggggca ttttaaaagt
    41641 ttatttaaag gaagtcttac aacaggaggt tttaaagctt tatttggtgg atttgtaggg
    41701 cttatagttt ctgttgctat atcaaaagac ataattgata taatagtaaa tacactaata
    41761 atagctctat caactaattt aatgaatctt ttggatttaa gaccaggaag ggcaataaaa
    41821 gcatatttat tcataatggt aattatattt ttaacattga caggatttgt tcaagttctt
    41881 ccattactta tagtaccaaa tgtacttgca tactttaatt atgatttaaa agcaagggct
    41941 atgatgggag atactggttc aaacgtcctt ggaatatcta ttggaatgct catttctttt
    42001 gggtatccat ttaacattag attaggatgg ttaatatttg tagttattat gcatatattc
    42061 actgagaaat actcattaac taagataata gaaaaaaata aactattaaa ttttatagat
    42121 aaattgggaa ggtagtatta tgataagcaa aagagtgggg attgttgaat caatagtaag
    42181 tcaaactgaa acactagatg atataagagt aaatataaat ggagaaatac aaagggcata
    42241 taattatccc aaaatatctg gaactataaa tataggtgac gaagtggttt taaatacaac
    42301 agcagtagaa ctgagcttag gtacaggtgg ataccatttt gtaataacta atttaaataa
    42361 tatagaatct actttaactg aaggtggaca tataatgaaa cttagatata cgcctcttca
    42421 aataaaagtg gattctgttg aggaacaaga aagtatttat catgataaat ttgcgaattt
    42481 taaaggatta gaaggtcttt ctgttgtagt agggactctt catagtatgt taactccatt
    42541 tgcagcttca tttaaaagaa ataatccaaa taaaaaatta gtgtatataa tgactgatgg
    42601 agcatctctt ccaatttatt taagtaaaaa tgtggatact ttaaaagaaa aaaaattaat
    42661 agatagtaca ataactatag gaaatgcgtt tggtggagat tatgaatgta taaatatata
    42721 tactgcatta attacagcaa aagaaatact aaaagcggat gcagtatttg tcagtatggg
    42781 acctggaatt gctgggacag gaacaaaata tggatttaca gggattgaac aaggctctat
    42841 tcttgatgct gtaaaaaaac ttgaaggaag agcaattgca attccaagaa ttagttttgc
    42901 tgacaaacga gaaagacatc aaggtatttc acatcatagt atgactgtat ttaaagaaat
    42961 tgtaaatgta aatgtagaca taccaataac tatatatgat gatgaaaaat tgaactttat
    43021 aaaagagcaa atcaatttaa atggtttaga caaaaagcat aatataattt atatagataa
    43081 taataaaacg aaagaggatt tagactattt taatctaaaa gtaaagagta tgggaagaaa
    43141 ttatgaacaa gatgaggcat ttttcaaagc tgcaagcaca gcagcatatt acttaatgga
    43201 ggtttaagat ggtattagaa gaaaaaacta ttagtagtga tagggtttat acaggtaaag
    43261 taattacttt aaaggttgat actgttgaaa ttccagggca aggatatcaa aaaagggagt
    43321 tagtagaagt tggtggagca gtaggaatag ttgcaatcac agatgataat aaagttgtgt
    43381 tagttaagca atttagaaaa cctatagaaa agccaatctt tgaaattcca gctggtaaac
    43441 tagaaaaaaa tgaaagtcca aaagaatgtg ctgaaagaga attaaaagaa gaaacagggt
    43501 atagtgcaaa aaatattaag ctaatacata aatttttcac ttcagcaggt ttttctaatg
    43561 agataatgtt tgtatattta gcaacaggtc ttactccagg agagaataat ttagatgcag
    43621 atgagttttt agatgtctat gaaattgagc ttgaagaagc atataacatg gtattaaaaa
    43681 atgacgttga agatgcaaaa acatctattg gattattatt agtaaaagat atgtttaaaa
    43741 attaatattt ataaaatgaa taaccctttg tcctaaagca tattatttta taaaggacaa
    43801 gggggaatta aattgagaag aacatataga aaaaatgatt ttagagaatt aaatagacaa
    43861 ataattatta taggattgtt gtttatgatg tctattgttg ttgggtctta cataaataaa
    43921 atattgccag gttctagtaa caatatatta aacaatataa atcctgctgt agagtattat
    43981 aatctaaata taagcataaa agatacagtg atacaaaatt taaaatcaga tgcaatcttt
    44041 atgggctcaa tagctctatt aagtctattt gtagtaacaa ttccagcagt gttggtagct
    44101 tttgtattaa aagggatgtc aattggttat acaataaata gttgtatatt ggcattaaaa
    44161 tttaaaagta taaaaatgat tttaataata ttatttaaaa atttgattat tattccatgt
    44221 gcaatcatat tagcattaat tagtttaagt tattttaaag aaatggttta tgaatttaaa
    44281 aagaaaaata gaaaaaatat gcaattttta attaagaggt atatactaaa tattataatt
    44341 ataatagcac tatcattggg gttgcaatta atattaaata ctgcaagtat tggtattatt
    44401 aagttcctag ctaaataaag gagtttataa tggatattat agagggatat atagattaca
    44461 taaaagataa aaaaaaatta tcagagaata cagtggcatc atactttatg gatataaaaa
    44521 aatatatgga atatataaat caaaaaagca ttaaactagt agatatagta gaaaatgata
    44581 ttataagtta cttaataaag ttggaaaaag ataatgtatc aatagctaca atagcgagga
    44641 tgatatcctc tataaaatct tttcatgatt atttattttt aaatcatata tgtacaaata
    44701 atcctgcaaa ggatataaaa aaacctaaaa taaaaaaaga aaatataaat atacttacag
    44761 aagaagaaat tgaaagacta ttaaattttc caaagttaac aacacctaaa ttgattaggg
    44821 acaaggctat ttttgaagta ttatatggta ctggtataaa agtatctgaa ttagtagaga
    44881 tgaatataga ggatattgac ctagatattg attatatata ttgtaattca tgttgtaaaa
    44941 atcaaagagt gataccactt tgtgatatta caaaacttta cttagaaaag tatctaaaag
    45001 aagcaagacc taaaatggct gtagaaggtg aaaaatcatt attcgtaagt tcattaggtc
    45061 aaaggtttac acgacaaggt ctttggaaag tcataaaaaa atattctaat ctagccaata
    45121 tagataaaaa tataaatcct acaatgctta gacattcatt tgctattcat ttgttaaatg
    45181 aaggtgctaa cattgctgtt gtaagtaaaa ttttaggaaa tgttaattta tctagtttgc
    45241 aagtatattt aaatcatata gataaaaacg tgagaagaga aataaaggag aaacatccta
    45301 gaaatgatgt tgatgtagaa ttacaaaaag cagaagctaa atagactata tagcaaattt
    45361 tataatttag aaggagcata tttatatgag cagagtaatt tggattgtaa ttgatagtgt
    45421 tgggatagga gcattgcctg atgctgaaaa atttggtgat agtaaggatg taagtaccct
    45481 tggaaatata tttaaggaat atccagatat tcagattcct aatatgagaa atttaggtat
    45541 aggaaacata gatggtatag atttttttga aagtataaaa gaaccaatag gttgttttgg
    45601 aaagtgtaag gaaatgtctc agggaaaaga tactactaca ggtcattggg aaatgactgg
    45661 tataatagtt gacaaaccat ttaagacatt tgaacatgga ttctctaagg agataataga
    45721 agagtttgag aaaaaaactg gaagaaaagt agtaggaaat aaaccagctt caggaactgt
    45781 aataatagat gagtatggag aacatcaaat aaaaactgga gatgtaatag tatatacatc
    45841 agctgatagt gtatttcaga ttgctgctaa tgaagaagta attcccctag aagaactcta
    45901 taatatgtgc aaaatcgcta gggaaataat gatgggggat aatgcagtag ctagagtaat
    45961 tgctagacca ttcataggta agaaaaaagg tgagtttgtg aggacttcaa atagaagaga
    46021 ttattcacta gacccatttg aaccaacagt tcttgataat ataaaagaat caggacttga
    46081 tgttttagca gttggaaaaa tagaagatat ttttaatgga aagggaatta cagatgctat
    46141 ccacactaaa agcaatatgg atggagtgga tgaaacttta aattatatga aacaagataa
    46201 taaaggtcta atatattcaa atctcgttga ttttgattct aaatatggtc ataggagaga
    46261 cccagaagga tataagaaag ctcttgaaga gtttgatagt agacttcctg aaataatggc
    46321 taatatgaga gaagatgata ttttaataat caatgcagac catggaaatg acccaacata
    46381 taaaggtaca gaccatacaa gagaatatat acctgttatg atttatggca ataagattaa
    46441 aaaaggtttt aatttaggag taaaagatac ttttgctgat attggagcaa ctgttgcaga
    46501 tatactaaat gtaaagttgc ctaaacatgg gtcaagcttt aaagaagatt tattttaaat
    46561 tataaaatga taaaaactta gcttaatagg atggagagat tggaatgttt gaaaagatag
    46621 cacaaagtag taaatttata aattctaaaa gtaatataaa acctaagatt ggtttgatat
    46681 taggttctgg actaggtgat ttagcaaatg atatagaaga ccctgtcaca attaaatata
    46741 gtgaaattcc aaacttccct gtatcaacag tagcaggaca tgctggacaa cttgtaattg
    46801 gaaaacttga aggaaaagaa gttattgcta tgcaaggtag atttcattac tatgaaggat
    46861 attctcagaa agaagctact tttccagtaa gggttatgaa agaattagga gtcgagattc
    46921 ttatagtaac taacgctgct ggaggcgtaa ataaagaatt taaagcagga gatttgatgc
    46981 ttataagaga ccatataaac tttagtggaa gtaatccatt agtaggaaaa aatgatgaca
    47041 gatttggtgc tagatttcca gatatgtcag atgcatattc ttctaaatat gtagatgtag
    47101 ttaaaaactg cgctaaagaa tgtaatatag atgtcaaaga aggcgtttat atgtttttta
    47161 gtggtccaaa ctatgaaaca ccagcagaag tgagaatggc acaaattttg ggagctgatg
    47221 ctgtaggtat gtctactgtt ccagaagtca tagtagcttc tcactctaat ataggagtta
    47281 ttggtatatc ttgtataaca aatatggctg ctggcatctt aaatcaacca ctaagtcatg
    47341 aggaagtaat agaaactact caaaaagtta aatcagaatt tatgaattta gttaaaacaa
    47401 cggttaaaaa tttataagtt aaagcttatt atagattttt tgaggaagtt tataataaaa
    47461 tagttaatgt ttaatttgaa aagaattaat aaaaagctgt cttgatatag aaagttattt
    47521 ctaataaagg acagtttttt tataatacta caacatttga aagtgtttta aagtttaata
    47581 tttatttaaa ttattatagg ttagaatgga gatttcaatt atgagaatgt atgatattat
    47641 aaaaaaaaag agagataacc tagagcttag taaaaaagag ataaactact ttatagaaaa
    47701 ctattcaaag ggagatatac ctgactatca agcttctgca ctattaatgt cgatttattt
    47761 aaataagatg aataaacagg aaactgtaca tcttacagaa gcaatgatga actctggaga
    47821 catgataaac ctatctgaga tagatggaat aaaggtagat aagcatagta ctggtggtgt
    47881 tggagataaa actaccatag ctcttatacc tttggttgct tcatgtggag caccagttgc
    47941 aaagatgtca ggtagaggtc ttggtcatac tggtggtact attgataaat tggagtctat
    48001 accaggtttt tcgacagaaa tggagataag taaatttatt gattctgtaa ataagtctaa
    48061 aatagcagtt tgtggtcaaa gtgcaaaggt agcaattgca gataagaaaa tatatgctct
    48121 tagagatgtt acagcaactg ttgataatat atcattgata tcatcaagtg taatgtctaa
    48181 aaagttagct tcaggagctg atgcaattgt gctagatgta aaaactggtg atggagcatt
    48241 tatgaagaca ttagaagagt cttttgagtt agctaaatct atggttgata taggtactgg
    48301 tatgaataga gatacaatag ggattgtaac agatatggat gaacctttag gttttgcagt
    48361 gggaaactct ttagaagtta tagaggcaat tgagacatta aaaggaaatg gacctaaaga
    48421 ccttgttgag ctatgcgaag tattaggagc atatatgttg gttttatcaa aggtagcaca
    48481 tgattttgaa gatggtgttg aaaaaataag agaatcaata aaatctggta ctgctataca
    48541 aaaactcaaa gagtttatag agaatcaagg tggtaataaa gatgtagtag atgattattc
    48601 tttattcaaa aaatcaaagt ataaatatcc agttaaatca actaaatcag gttatataag
    48661 taaaattaaa gctgaagatg ttggtgtatc ggctatgatt cttggagcag gtagagaaac
    48721 taaagatgat attttagatt tatcagcagg gataatttta gaaaagaaag taggagatta
    48781 tgtaaatgaa ggtgaagttt tagcttacat gtattataat gatgaacaaa agctttcatt
    48841 ggcaaaggga agatttattg attcctactc tattgtagat tcaaaaatag aaaaaaataa
    48901 attaatatat ggtattgtaa ctaaagaaga gattaaaaag ttttagaaaa ttttagaaaa
    48961 gtgattataa aaggcctaac atgtcaaaaa taatgttagg ttttttattt tttgataaac
    49021 tataaattat accaaaaata tatattttaa aacatttttt acaatataaa taagtttatt
    49081 ctacaagatg attgaaaatt aaagtatcta gttttataat agaaaatgga taaatataca
    49141 taaggagtag attatattat gaactttaaa gaaaatagat tgaaaatagc agtattaata
    49201 attgttattt tgattatctt agcaggtata tttgtgttta tacaaatagg tccttatgat
    49261 aaaaataaca aaaaagatgt aattatcgac gttccaagtg gagcatctgt tggaaaaata
    49321 tctgacatat tatatgaaaa taaattaata aagaatgaac tattatttaa acttttggta
    49381 aaggttagca ataaagctcc gtctataaaa tcaggaacat acttacttaa tcaatcgtat
    49441 tcaaacaatg atataataag tcttttagtt tcaggtaaaa tatatcagga tggtataaaa
    49501 gtgactattc cagagggagc tacatctaaa gaaattatag caatgttagt aagtaaaaat
    49561 ttaggagata aagctacttt tgaaaattta ataaaaaaac ctcaagaatt ttatgataaa
    49621 tttccatatt tgaaggaaga tggaataacc tctttagaag ggttcttgta tccagaaact
    49681 tattatttta attcaaagaa acaatcagaa gaagatattt taagcgaaat gttaaaagta
    49741 tttgacagta aatacacgga caagtttaaa aagaaacaaa aagaattaaa tatgactctt
    49801 caagaagtaa tggaaatggc atcaataatt gagaaagaag ctgttcttga caaagacaga
    49861 cctataatag caagtgtgtt ttataataga cttaaggtag gtatgcctct tcaatcagat
    49921 gctacaatac aatatatttt tgaagagaga aagaaaattg taacatatga tgatttaaaa
    49981 attgattcac catataatag ttataaaaat aagggattac ctcctacacc aatatcaaat
    50041 cctggtataa aatctattga agcagcatta tatccagaga aaacagacta tttatatttt
    50101 gtagctaaga ttgacggtgg aaataattat agtacaaact atcaagacca tttaaaatac
    50161 gttaaagaat ataaagaagc aagggataaa caatcaaaag atacaaaagc aacaaataaa
    50221 gaaaatacaa aaaaataaac catgattata aaaagtctaa cagggtaaga ataatgttgg
    50281 gcttttttat tgaaaattgt tattcttaga tttataataa agaaagtgta aatatatata
    50341 acaatatgaa tttaaaaaat aataaattaa tataaaactt gaatatttat tattttaggg
    50401 agtgttttta tgagtaatat agttaatgat ttggttgaag attatataag agtgacatta
    50461 aaagaaaaag aaggattttt aaaagattta gaaatttatg cagaggaaaa tagtgttcct
    50521 ataatacata aagaagtttc agatttatta aaagtcttgt taaaggttca aaaaccaaag
    50581 agaattttag aagtaggatg tgcaattggt tattcttcta ttttttttgc aactattata
    50641 ggaaaagatg cagatataat aactgttgag agaaatgaaa aaatgataga aaaagcaaaa
    50701 gaaaacataa aattagctgg atttgacaat aacataacta tactagaagg agatgcagaa
    50761 gaaaaactta gtcaagtcca aggtgaattt gaccttatat ttatagatgc agccaaaggt
    50821 caatataagc tattttttga tttagttata gataaattaa aagatggggg acttttagta
    50881 tctgataata ttttgtataa aggtatggtt gctcatgatg attttgttgt aagaagaaaa
    50941 aagactatag ttaaaagaat gagaaattat ttagattata tatgtaattg tgactattta
    51001 agcacatcat tggtaccaat aggtgatggt gtagcactaa gttataaaga aagtaaaaga
    51061 ggtgatgtag atggaattaa ataaagtaga acttttagct ccagcaggtg atttggagag
    51121 attgaaaata gctataacat atggagcaga tgccgtttat ataggtggag aaatttttgg
    51181 aatgaggtct gcagcgaaga attttagtaa ggaagatatg gcagagggag tagcttttgc
    51241 acatgaaaga ggcaagaaag tattcgtaac agtaaatata atacctcata atgaagattt
    51301 tctacaatta gaagactatt tgttggaact agaagaaata ggaatagatg cagttataat
    51361 agctgaccca ggagtgctta gtgtcattaa aaaagtaatt ccgaatatgg aaatacattt
    51421 aagtacacaa gcaaatacaa ccaattatct aagtgcaaac ttctggtacg agcatggaat
    51481 aaaaagagtt gtagtggcaa gagaattatc ttttgatgaa atatctgaga taagagcaaa
    51541 aacaccttta gatatggata tagaagcgtt tatgcatggt gctatgtgta tttcttattc
    51601 tggcagatgt ttaataagca actatatgac tggaagagat gcaaacaaag gttcttgtgc
    51661 tcaatcttgt agatggcaat atcatttggt ggaggaaaaa agacctggtg agtattttcc
    51721 aatatacgaa gatgaaaggg gtacattctt ctttaactca aaagatttat gtatgataga
    51781 gtatatacca gagttaatca aatctggtat aacaagttta aaaatagaag gtagaatgaa
    51841 gactgcatac tatgtagcta ctgttgtaag agcatacaga atggcaatag atgaatttta
    51901 cagagaccca gaaaactgga agttcaatcc aatgtggatg gaagaactaa aaaaaggtag
    51961 tcatagacat tttacatcag gtttttactt gaataaacca acaacagaag accaaaatta
    52021 tcaatcagca tcatatgtta gaaactatga ttttataggt atagttagag aaacagaaga
    52081 tgaagatggt cttattgttg ttgagcaaag aaataaaatg tgtgttggtg atgaaataga
    52141 agttatggga ccatataaag aaactatgtt tactaaaatt gaagaaatgt acaatgaaga
    52201 aggagaagct atagaatcag ctcctcatcc tagacaaata gtgaagttaa aactatcagt
    52261 aaaagttggt aaagattata tgcttagaaa agttatagaa gaaaaggttg aagaataata
    52321 aaaaattgat aaaaatagta ttagcccctt agaaattgtc aataatgaaa ttatctaagg
    52381 ggtgatttca tgtcaaaaaa gaagactcca tttttgaaaa aagtgggaaa gagaagctgg
    52441 tgtatattta ctataatttt aataatttat agtgttttaa tttataggct agttgatata
    52501 caagtattaa aaggtgataa atacaaacaa agtgttgaat cacaaagcgt tgagaaagtc
    52561 gagttaaata gtggaagagg aataatctat gatagaaaca acaagaagct tacagataca
    52621 agtaaatctc aggtattaat tgttgaaaaa gaaaaattaa ataataacta taaaattttg
    52681 gagcttatta agaaagctac taagatgaat gatttagata tatataaagc tgtacaagag
    52741 caattgacac gccctataat acagattcag actaaaaata tcgataagag tatgaaaaaa
    52801 gaacttgaga aaaatggaat aatggtagaa gaaaaaacta tgaggtacgc aaaagatggt
    52861 ttattatcac atacaatagg atatataaaa gaagatgata aatcaggtca atcaggaatt
    52921 gaaaagagta tggatagtgt acttagaaat tcaaatgaaa agtatataag tgcttttaaa
    52981 gctggagatg caggaaatga aaaatctcta aacatactaa agggaagtgt aaaaactgtt
    53041 gataataagg ataaagatag acatctaaaa actactattg attataacat tcaaaaaaaa
    53101 ttagaacaaa tactaaataa agaagaaaat cctacagcag caataatctc ggaagcatct
    53161 acaggtgaaa ttcttgcaat gtgctctaga cctaattttg accaaaatga catatcaaaa
    53221 agtttaaaag gaaaaaatgg agaatttgaa aatagagtta taaaagcgac atatccacca
    53281 gggtctgtat ttaagatggt agttttattt tctgcacttg aaaatggtgt tatagatgag
    53341 aactatactt acaactgtac aggtaagact aaagttggga atactaatga aatactgcga
    53401 tgtaataaaa gagatggtca tggtttccaa aacttaagac aagctttttc taattcatgc
    53461 aatcctgcat ttttagatat agctatgaaa cttggaaaag aaaagatact caaatctgct
    53521 gaaaaattac atttatttga aaaggttgat attggtcttg atgaagaaaa aattagagaa
    53581 gctccaaaaa acatatcaat aagaaattta gctataggtc aagaaaatat agaatttaca
    53641 ccacttcaaa taaatcaaat gactcaaata atagctaata atggaacatt caaaccacta
    53701 tacttatata aaagtcttgt ggacaataat atgaatacaa taaaaactta taagtcttca
    53761 aaaaaagaag aacttatttc tccctatgtg tgtacacaag ttaaagaata tatgaagtct
    53821 gtatctagga ttggtacagc taaagaccta aaagatattg aaggtggttg tggagttaaa
    53881 actggtacag ctcaaagtag tttaaataaa aaagctatag accacggatg gataacagga
    53941 ttttatcctg aagaaagacc taagtatgta ataactgtgt tagtagaagg aactcaaaaa
    54001 ggaaataaat ctgcaacacc tatatttaag gaaatatgtg aaagtataaa ataaattatg
    54061 tactataaaa tttaaggata tatcgtaact ttgattttag atagaaaatt ttgtctaatg
    54121 atgtacgata tatcctttta aaatatagta ttaactttct tgaacaagct ctttttctag
    54181 ttttttaaga gctttttttt cgattctaga tacatatgac cttgatatat cgagtttttg
    54241 tgcaatttct ctttgtgtct tatagccata aggagttaac ccatatctta actggacaat
    54301 ttctctttct ctaggagtaa gaattttgtt tagttgttcg taaagttttc caacttgaac
    54361 ttttagttca acttcatcaa gaacatagtt agcctctgta ccaagtatat ctaaaagact
    54421 tatttcatta ccttctttat ctgttccgat agggtcttgt agagatactt gagttttatt
    54481 ttttttgtta gatctaatat tcattaaaat ctcattttca atacatctag aagcatatgt
    54541 tgctaatcga gttcctttat ctatgttata agtttctata gctttaatta atcctattgt
    54601 acctatggat attaaatcat cctgatcttc cgttgaatta ttatatttct ttgctatata
    54661 agctactaat ctcatgtttc tttcaattaa tgtatctttt gcacttttat cgttttctat
    54721 tttaaattta gttaaatact caatctcttc ttcaggggtt aagggttttt caaaagattt
    54781 aagagctgcc aataggtcac ccccttttca acggtcactt taaattatat gaaggagact
    54841 tatccaagtt gactgttatc taataaaata atatgcatat ttttagaatt taaaacatat
    54901 atttgcaaac ttttgaatgg aatatgacat aaagagtggg aatttaaatt taagtttttg
    54961 ttgtatatat atgaaataag gcgaagaaat tattgattta taaagtataa attggaattg
    55021 aggtgtcaat aaatataaaa ggaaatagta tttatatatg ttttggtgtt gaagtaaaag
    55081 attaatgcaa agcattagag tctataaaaa tatgaatata ggaggtgtaa ttttacaata
    55141 cttaaaaaag taaatgtaat taattgtttg tataaagttg attacaagca aaagtatcag
    55201 tcatagttaa tactgttaag ggtgaaggtg gtgtgttaat ttatatatgt atgggaagaa
    55261 attttgatta caatgaaaaa acttacaaaa gatatttatg aaaaaactta tagttaaatg
    55321 tttatatata aaatattatt taggggttgt ttttattatt gaaaataaga aagagtggtt
    55381 ttatatcaat tgaatgtata ataagtattg ctatattata tgtggctgtt tatttagttt
    55441 ctacatcatt gtataattgt tatagtttta tcagtagaaa tatatctgac agagaaatgt
    55501 taagtacagc aaaaaaatat atagaagatg agaagtatag aatacaaaat agtaagtatg
    55561 agttaattga agataagata gaaaaaaatt acataaatgg atatgaaatt aacagtaaaa
    55621 tagagcaaat tttagattat tatcaatgct atgaaataaa tatagagata aaaaatgaat
    55681 ttaaaaaact gaggtttaat agctatgtta ctagaaaata aaggctctat attaataata
    55741 acattgataa tattttctat tataagtact gtgtgcatta tgtgtatagg tttaatttat
    55801 acacataata atatgtttga gttaggatac aaggacattc aactaaaaga aatttcttta
    55861 agtggaatag aaatatcagt aagtaatgta ctttcttgtg ttgaggaagc tattgatgta
    55921 tctaataatg aagacgaatt tagagaatat ttcttaggaa ataatatgat tgaatgtata
    55981 aaaaaaataa aagatacatc ttatagtagt ttagaagaac tttctttaaa agtagaaaat
    56041 aatactattt atgacagagg agattttttt gaatttgata tagaaagtaa tgttagagaa
    56101 aaagaatttt taaaagcaat aaaagtaaga gtgaaaatca aaaatccatg gataggaatt
    56161 gacattgaag attatatgga taaatctaat aacaataaaa ttgatgacaa aacattcaat
    56221 aattataaag catctgaaaa taatgaaatt ctaaatcaat ttaaaaatga aagtgaaaat
    56281 ataaggaatc aagaggttgg tggatttaca gaagaagatg aagaatatga agaagaactt
    56341 aaacaaaaca taattgaaaa tataaagaag aattttgatg aaaaaaacct agtacaggta
    56401 tataagtata ggggtgtata actttgaaaa aagaaggaat gtgactgtaa tagaattaat
    56461 agtatctatc agtataatac tcttgatagt tacattatct tttccaaaag ataatcttga
    56521 aaatcataaa ataaatttat ttgcacgtca actttgttca gatataaggt atgttaggcg
    56581 aattaatatg tttagcaact acaatacata tatatattat ataaatcaag gtaaacacga
    56641 aggttatgta ttgagaaaag atggtaaaaa cattaaatca ataatgctac ctaaaaatgc
    56701 aaaaatagct aggagtattg aaataataaa gtttaaatct gatgggtcgc ctcaaaaggc
    56761 gtctacaata gagatatata ataatagatt aagaaaaact ataacaataa cacctgtaag
    56821 tggaagagta cttctgaaag agggaaaata tgaaacataa atatggttac ttgcttttgg
    56881 aaagtgtcgt atcattgtct tcaatggtga taattatact agttttatat tctatatttt
    56941 tgtctacaat aaacttaaag ttaaaagtag aagataagat agaactacaa caacaaagtc
    57001 ttgaaatcat aaaatctatg gaaggaatta ttagcaattc tatgggaata atgaatgtat
    57061 ctaattatga agaaacattt aaaaagacaa catctataaa atgtagatat ttagatgaaa
    57121 ataataatga agaaggcata agtaataaag aaattatatt gaatgaaaga cgaaataagt
    57181 tatttgtaaa ttctttaaat ggcgaaagta gtcaagcagg tggttatgaa attggagatt
    57241 atgtagatga gatgtatgta tcaattacta ataatggtca atatgttaat attaaattga
    57301 aattatcaaa acgtagtcaa aaatatgaga ctgatttcaa aataaaagta tggaatttta
    57361 gtgaaagtat ataaaaatac ataaatttaa gagaaagaag tgacatcaat aagtcatata
    57421 aaatataatt attgagaact atataactaa ataatatcaa tatgtaaagt gtatagatta
    57481 agaatataga ggataataat aaaaatatag aataagtaat ttgccaaata cttgtttata
    57541 ttgtataact tatgatatta tgatattagt aaaaatttgt aatcctgact tgacagaatt
    57601 caagtaagag atataatttt aaaggcatag taatgtaaaa tttactaaaa aataagaaat
    57661 ttattttaat atggaggaac aaaaaatggt atcagcaggt gattttagaa aaggtgttac
    57721 atttgaaaaa gatggacaac catgtttagt agttgatttt caacacgtta agccaggtaa
    57781 aggagctgct ttcgttagaa ctaaatacaa aaacttaaaa acaggagcta taagagaaga
    57841 aagtttcaat ccaagtgaaa aattccctaa agctgttata gatacaagac aaatgcaata
    57901 tctatacaat gatggtgagt tatattattt tatggatcaa gaaaattttg aacaaatacc
    57961 attaaactat gagcaagttg aagatgcaat taagttctta aaagaaaatg aagttgctac
    58021 aataagattt taccaaggac aaccattcca agtggaagcg ccaaactttg cagagctaga
    58081 agttacagat acagagccag gtataaaagg tgatacagca agtaatgtaa ctaaagcagc
    58141 tacagttgaa actggagcag ttgttcaagt tccattattt ataaatactg gagataaagt
    58201 aaagatagat actagaacag gtgaatattt atcaagagta taaaaattta tgtatataaa
    58261 agcttatatg tcttaataat ataagatata tgagctttta gtttatatat aaaaaagaaa
    58321 gcgaggggtg ttacatgaaa catttatatg aagaagttgc atacttaaaa ggcctagcag
    58381 aaggactaga aataagtgct gaaagtaaag aagggaaaat gatacataaa atagttgatg
    58441 cattagaagt atttgcagat gctattgtaa cattggatga agaacaagaa gaacttcaag
    58501 attttgttga atctatagat gaagatttag cagatttaga agaagatatt gctgacatgg
    58561 aagaagatct ttatgaagaa gatgacgatg aggatgatga ggacttcagc tatatagaaa
    58621 tggaatgccc aaattgtgga gagttagtag aaatagacga agatttgtta tatgatgatg
    58681 aagtagatgt tgtttgtcct gattgtaagg ctgtgatatt atcatcagaa gatgattgtg
    58741 atgatgattg tacatgtggt ggttgttcaa gttgtgatga tagagagtaa aaattcataa
    58801 gaattaaaac tgcctatgat gcctatgaga tattttgctt cataggtagt tttattttta
    58861 tgaggaaggg tattatgtat tttggttttg caatacttgg acaaaaatag tacactagaa
    58921 tttatagaat aggattttgg agggatgtaa atatgaaaat aagtaaaaaa ttactagata
    58981 atatacaaag atttgaaaat gttataaatt ataaatttaa aaataaagaa tatatactag
    59041 aagctcttac tcatagttca tattctaatg aaaataaaaa atataatttt aacgaaagat
    59101 tggaattttt aggggattcg gttttaggca tagtgataag tgattattta tttaatgaag
    59161 aagctaatct gcccgaaggg gaactaacta aacttagagc aaatatagtt tgtgaagatt
    59221 cattaagtga agtagctaat gatataaatt taggtattca catgttatta ggtagaggag
    59281 aagaagcaac aggaggaaga cataggactt caatattagc agacgcattt gaagctgtaa
    59341 tagctgctat atatcttgat ggaggttttg aaagtgcaag acagtttata cttcatcata
    59401 tggaaaatat aatttatgat tcaagaaaag gaaatatatt tagagactac aaaacgcatc
    59461 ttcaagaggt gttacaaggg aatggagaaa ataatatctg gtacaggctt atagaagaaa
    59521 aaggaccaga ccataataaa agatttgtaa tggaagttgg aattaatgac gatgtacttg
    59581 gtataggaga aggcaagagt aaaaaagaag ctgaacagtt agctgctaaa atagctttaa
    59641 agaaaaaatt atgggaaaaa taaatataat atgtaaaaat ataaaaagaa atatttatat
    59701 tagaaggatg ttgtagatga aaaagagaat tatacctata tttgttcctc acaaaggatg
    59761 tcctcatgat tgcatatttt gtaatcaaaa aaaaataaca ggtgtgagta ctgatgttac
    59821 tagtgaagat gcaagaaata taattgagga atgtttagag actatagata aagatgcaga
    59881 tgtagaaata gcattttttg gtggtagctt tactgctata gatattgata tacaaaaaag
    59941 tttattatca gttgctaaag aatatgtaga aaaaggtctt gtaaaagata ttagaatgtc
    60001 tacaagacca gattgtattg atgaagatat attaagtatg ttaaaagaat ataagacaag
    60061 tataattgaa ctaggagtac aatccttaga tgaaaaagta ttattagata gtataagagg
    60121 tcatcaatct gaaattgtat acaagagttc aaagatgata aaaaatagtg gaatcaaact
    60181 tggattacag atgatgattg gtcttccagc tgacacagaa gaaaagtgta tatttacagc
    60241 aaaaaaattt gtagagctaa aaccagattg tgttagagtc tatccaactt tggtagtaaa
    60301 agatacaggt cttgaaaagt taatggaaca aaataaatat aatccattta ctcttgaaga
    60361 gagtgtaaat atagtaaaaa aagttcttgt actgttttat gttaataata tcaatgtaat
    60421 aagagttggg cttcaagcta ctgatgatat acaaattgga aaagctgttt tagcaggacc
    60481 atatcatcct gcatttagag agttggtaga agcagatatg ataaaagatt atttagaatt
    60541 tgttattttg caaaataaaa atataaagca aatgttggtc aaatctaata aaaagaatat
    60601 ttctaaaatc ataggaaata aaaaaacaaa tgttaaatat atggaagaaa aatttggtgt
    60661 gcttttaaaa acacaagaat cagatttaga tataaatcaa ttagaaattg tgttagatgg
    60721 gaaaagttta attagtgcta atatgagaga cattcataga aaattgtatg acatttatga
    60781 cctttagttt taataatgaa gggagagaaa agatttgtat ttaaaaagac tagagttaaa
    60841 gggatttaaa tcctttccag taaaaacaga tattattttt aaagaaggaa taacagccat
    60901 agtaggacca aatgggagtg gaaaaagtaa tatatctgat gctgtaagat gggtattagg
    60961 agaacagagt attaagagtc ttagaggtga taaactcgaa gatgtaatat ttgcaggtac
    61021 agatacaaaa aaacctatga attattgtga agtggctctt actattgata attctgaaaa
    61081 tcaattggaa ttagatttta cagaagtaac tataagaaga agggcttata gaaatggtga
    61141 aagtgaattt tttctaaata ataaaagttg tagattaaaa gatataaaag aagtcttttt
    61201 agatactggt attggaaaag atggttattc aatcatagaa caaggaaaag tagatgaaat
    61261 attaagtaat aatcctttaa gcagaagaaa agtttttgat gaagcttgtg gcatatcaaa
    61321 atatagatat aaaaaacagg aagcagaaag gaatttaagt aatacaaagg aaaatttaga
    61381 aagaatagat gatgtatata tagaaattga aaatcaatta aagcctcttt ttaatcaaca
    61441 gacaaaggca aaaaagtact tggaaataag tgaaaaatta aagacacttg aagtaaatag
    61501 ctttataaga gaaattgaag gaatagaaaa agaattaagt gaggttaatg aacatcgtaa
    61561 ggttattgaa aaggagctca atgaaaaaga agaacaaaaa aatgttgtag agaaaaagca
    61621 agaagatatt aataaagagg tagaggtatt acaagatgta attgaaaaat ctgtagatta
    61681 tataaattca attaaaggag ttatatcaaa aaaagaatcc caaataaatt taattaagga
    61741 aagaataaga aattttacga atgaaattag tagaaaaaat ttagaaataa atgatataaa
    61801 agagaagcta aatgaaaata agcaatacat aaaagaatta gaaagtaata aattatcagg
    61861 tagtgaagaa ctatctacct tgcaggaaaa tataaaagta ttggaaggaa gtaaagataa
    61921 acaaaaaatt aagttagaat ccctaaataa tgagatagaa ttattgaaag aaagtataat
    61981 tgatatatta aataagaaac aagagtttag taataagctg tctactttaa acgcaaataa
    62041 agaaaatatg aatatcagag atgaaaatat aaattcagag ataacagagt taaacaaaaa
    62101 tattgaaata aaatcatctg aattagatac tataaataaa gaatttaata tgcaaaatga
    62161 aaatttaaag aatgtaaata atagacataa agaattatca attaatttgc aggattcaat
    62221 tagtgaacac aataaactag aagatgaaat acagaaaagt aaatataatt taaatggata
    62281 taattcaaag ttaaatgtct atatagatat ggaaaatcat tatgaaggat ttaatagagg
    62341 agtaaaagaa gtactaaaaa ataaaaattt aaaaggagtt catggagcat taggacagat
    62401 tataaatgta cctgaaaagt atgagaaatc tatagaagca gctcttggtg cttatatgca
    62461 aaatataata actgataatg agtttagtgc taagtctgca ataaactatc taaaacagaa
    62521 taatttaggt agagtaacat ttcttccatt aaatataatt aaatcaaata aaataagtct
    62581 aggaaattta aaagcaaata ctaagttcat aggaatagca agtgatttaa ttacatttga
    62641 tgaaaagtat agaaatataa ttgaaaatat acttggaaga acaatactta taaataatat
    62701 agatgagggc ataaaatttg caaaagaaac tggtcatagg tttaaaatag taactttaga
    62761 tggtgaaatc ttaaatccag gaggttcttt gactggggga agtctaaaaa ctaatgggaa
    62821 tatactatcg agaaaaagat acattaatga atatacagaa aagataagta atatcaagaa
    62881 tgaaatttca catctagaat taaaaagaga atctttagac aaagatgtga aaaatataaa
    62941 aaatgaaatt gattcacatg aaagtaaaat aaaagattta gaaaaaagta taataataaa
    63001 aagtacaagt ataaagaatg ttgaatctga aattgaatcg ttaaaaggta gtattactaa
    63061 attagaaaat gagaagaatg atttaaattc taacctaaat tatacacttg aaaaaagtga
    63121 tgatgttaga aaagatatgg aagagttaga tgatttatac aataaaaata aagaaaaaat
    63181 tgatgcattg aatgaggaaa taaaaagata caatgattta tatgataaag aaaaatctga
    63241 atttgatgaa ttgaacttaa gtttagtgaa gaaaacagaa gtttacaata gtatagttag
    63301 agatataaaa agaatatctg gtgaaaattg tgagttagaa gaaaaaaata aacaattaga
    63361 agagtcatta aattatgaag aacatgaaat aattaaatta caagattcta tactcactga
    63421 agaaaaagaa aaagaaaatt taacaaaaca actaggggat agtaatagaa atcttgaaac
    63481 tagaaaaata gcaaaagatg atttaaaaaa tagttttgat gaaattaata aagaattaaa
    63541 aactatagat agacagcata tagaacttaa agaaagttta tttaaagttg gtggaagatt
    63601 agaaagatta aaaactagtc aagacacata tataaataag ttgtttgagc aatatgatat
    63661 gaccttagta caagcattgg aaattaaaga tgaagatttg gatatagata gaaaattctt
    63721 agaaagtcta aagagagaaa taagaagtct tggaaatata aatatagact ctataaagga
    63781 atatgaggaa ataaaagaaa gatacgattt ttatagcgaa caaaagcaag atttagaaga
    63841 gtctatggaa gagatagaaa aacttataca tactttagaa gaaaatatga aatctgaatt
    63901 tgaaattaag tttgaagaaa taagtaaaaa ttttaaatat gtatataaga gattatttgg
    63961 tggaggttgt ggagaattaa ctattttaga taaagaaaat ttattagaaa gtgatatact
    64021 aataacagct caacccccag gtaaaaaaat gaaaaattta aacctattat ctggtggaga
    64081 gaaagcttta acggcaataa gtatattatt tgctatattg attacaaagc caacaccatt
    64141 ttgtatatta gatgagattg aagcgccact tgatgacgca aatatattta gatttggaga
    64201 atttttgaag gatttatcta aagagactca atttatatca gtaactcata ggagaggaac
    64261 tatggaagct gctgattata tctacggagt tacaatgcaa gaaaaagcca tttcaaaagt
    64321 tattagttta aaattaaaag aagctcagga aataacagat attatataac ttagattgac
    64381 ataggaggaa taatagtgtt aaaaaaatta tttggttttg gaaaagacaa ggaaaaggaa
    64441 atagaaaaaa aagatgctga agaagaaata gaagttgaag acagtgttga taatttagaa
    64501 aacttggaag aaactatttt ttcaggactt gaagaagaag tgatagataa agtggaagat
    64561 gttgaagaaa aaaatgagga aagtgtcaat aatgaaggca ctgaagaaat cgaaaacttt
    64621 gaaaaaatag aagttgagat gaatagtaat ggaaaagaag tagaaaatat ttcaaataat
    64681 gattctcaag aagagataat cgaagaatta gaaaattatg atgaaattga gtctaaagag
    64741 atagaagata aagaagataa gaaagttaac ttgtttgaaa gactaaaaca aggattgaca
    64801 aaagcaaagc aaggaataac tgatagaata gatgaagttt taaaatcata tacaaagata
    64861 gatgaagaat tacttgaaga tttagaggaa attttaataa cagcagatgt tggtgtaaat
    64921 acaactatgg atataattga aagactaaga gataaaataa agcaaaaagg tattactgaa
    64981 ccaataaagg taagagaaga acttaaatct atagttgaag atattcttac aaatgaaaac
    65041 tctacactag atatagaacc agcaccatgt ataatattaa tggtgggtgt aaatggggtc
    65101 ggtaagacta ctacaatagg taaactagca aatagataca aaaaagatgg taaaaaagtt
    65161 ttattagcag cagcagatac atttagagca gcagcgacag agcaattaga aatttgggca
    65221 aatagaacca atgtagacat aataaaacat caagagggag cagaccctgg agctgtagta
    65281 tttgatgcta taaaagctgc aaaagctaga aaaacagatg tattaatatg tgatacagca
    65341 ggaagattac acaataaggc taatcttatg aatgaacttg gaaaagtatt taaaatagta
    65401 gatagagaat ttccagaagc aaaacgtgaa gtacttcttg tggtggatgc tacaacaggt
    65461 caaaatgcag ttgttcaagc aaagacattt aaagaagttg cagatataac aggtatagta
    65521 cttacaaaac ttgatggaac tgcaaaaggt ggagtagtcc ttgcggtaaa atcagaagta
    65581 gatgtacctg taaaacttat tggagttgga gaaagtgtag aagacctaca agatttcaat
    65641 gcaaaatcat tttcagatgc attatttggt aactaatgtt cttttaaaaa taatggttga
    65701 caagagtgtt gttatgatat aaaatacaat agtgtaaagt aaataacctt tacagtatac
    65761 tgctaggaag tgtaagatat gaatatagaa aaaatggtcg aaattggatt gttatttgaa
    65821 cagtataaag aattattaac tgacaagcag aaagaaatag ttgctctata ctatgaagaa
    65881 gattattctt taggtgaaat tagtgaaaat ctgaatgtat caagacaagg tgtttatgat
    65941 accttaaagc gttcagaaaa aatactaaga gattatgaag aaaagttaca cttagtatca
    66001 aagattcaag agcaggaaaa aaatattaag attataaaag ataaaattat tgacattaaa
    66061 gaagatttat tgcacaatag agattgtgct aatttaatcc ctaagctaga aaatatagaa
    66121 gatgtatgta gggagatgat aaaatgatat ttgaaggatt gtctgataaa ttacaagggg
    66181 catttagtaa gttaaaatct aaaggaaaac ttacagaagt agatgtaaaa aatgctatga
    66241 gagaagttaa acttgctctt cttgaggcag atgttaactt taaagtagtt aaagatttca
    66301 taaaaaaagt tcaagagaga tgtgttgggc aagaagttat gcaaagctta actccagctc
    66361 agcatgtaat caaaattgta aatgaagagc ttacaagttt aatgggagat gtacaaagta
    66421 aagtaatgat ttcctcaaag cctcctacaa ttttaatgat ggttggattg caaggtgcag
    66481 gtaagactac tacagcagga aaacttggag gatattttaa aaagcaaggt aaaaaacctc
    66541 tattagtagc ttgtgatatt tatagaccag cagctataaa gcaacttcaa gttgttggag
    66601 aaaaattgga tatacctgta ttcaatatgg gagataaaga aaatccagta aatattgcga
    66661 aagcaggttt aagccatgcg attaaaaatg ctaatgattt agttattata gatacagctg
    66721 gtagacttca tatagatgaa gtacttatgg atgagttaaa gtctattaaa tcagaagtta
    66781 agccacatga gatacttttg gttgtagatt ctatgacagg tcaagatgct gtaaatgttg
    66841 cagaaagctt caatgaggca cttggtgttg atggagtagt attaactaaa ttggatggag
    66901 atactagagg tggtgctgca ctttcaataa gagcagttac acaaaagcct ataaaattta
    66961 tggggatggg agaaaagcta gatgatatag aacctttcca cccagataga atggcatcaa
    67021 gaatattagg tatgggagat gtcttaagtt taatagaaaa agcacaagaa aatatagact
    67081 tagagaaagc taaagaatta gagcaaaaaa ttaaaaaaca agagcttgat tttgaagatt
    67141 tcttacaaca aatggaacaa atacaaaata tgggacctct tgacaagata cttggtatga
    67201 tacctggtat gggaaatgta aaagaccaac ttggagatgt agatttgaat ggcaaagaaa
    67261 tgaagagaac aaaagccata attcagtcaa tgactacata tgagagaaga aacccaggag
    67321 tattaaatgc ttcaagaaag aaaagaatag ctaaaggcag tggaactagt gtacaagatg
    67381 taaatagact cataaaacaa cttaatgaaa tgaaaaaaat gatgaagatg tttgctggtt
    67441 cacagaagag tatgaagaaa aggggcggct taggcggttt accttttttt aaataaaata
    67501 taaaaaagta aaaattattc ggaggtgact gtaatggcag ttaaaataag attaaaaaga
    67561 atgggagcta acaaaaaacc tttctacaga atagtagtag ctgattcaag agctccaaga
    67621 gatggaaaat ttatagaaga aataggatac tataatccaa tttctgaacc taaacaagta
    67681 agaataaatg atgaaaaagc tataaaatgg ttagctactg gtgctcagcc aacagaagta
    67741 gttaaaaaat tacttgtaaa aaacggagta atagaaaaat tcgaagcttc taaacaagca
    67801 aaataatttt ttcttggcaa ttagtttaag taagggctca ttgctaaggt tactttagga
    67861 gatgaaatat atgaaagagc tagttgtaga tatagctaag gctctagttg ataatcctga
    67921 ctcagttgtt gttgaggaat ttgaagataa tgatggtatc gtcttaaagc ttacagttgc
    67981 tcaagaggat atgggtaagg ttattgggaa gcagggaaga atagctaaag ctataagaac
    68041 tgtcgtaaga tctgttgcaa atagagaaaa tataaaagtt tctcttgaga tagtataaaa
    68101 taggaggatt aggtataatg cctagtcctt tttatataaa tgcgtagttt aagattttat
    68161 gatgatatga ccacataaga ttaaattttt taagaaggtg ataacatgaa agaaaaatta
    68221 actcatttta aggtaggtca aatagtaaat acacaaggtt taaaaggtga agtaagagtt
    68281 tatccactta ctgatgatat agagaggttt gatgaattaa aagatttcta tctgggaaaa
    68341 gatttaaata ataaattggc tgttgaaaaa gtaagataca aaggttctat ggttataatg
    68401 aagataaaag gcatagacag catagagaaa gcagaaaaac taaaaaataa atttatgtat
    68461 gtatctagag aagatagcag agagcttgaa gaaggcgaat tttttatagc agatatgatt
    68521 ggaatggaag ttttaactgt agatggaaaa tatgtaggaa tactagaaga tgttcttcaa
    68581 tactcagcaa atgatgtcta tgtagtaaaa ggtgaggaag ataaagaatt tatgatacca
    68641 gctataaaaa aatttgtacc tacaatagat attgatgaaa gaaaaatgat tatagaccct
    68701 attaagggaa tgatagatta ggtggtaata tgagatttca tataatgaca ctttttccag
    68761 aaatatttaa ttcgtacatg gatgaaagta taatgaagag agcagttgaa aaaggtataa
    68821 ttgaggttca tatatataat ataagggatt tttctaataa taaacataaa aaagtagatg
    68881 attatccatt tggaggagga gcggggatgg taatgactcc tcaacctata tatgacacat
    68941 ataagcatat aataacaact cataatataa ataacccaag tgtaatttat cttactccaa
    69001 aaggtaaggt atacaatcaa tctatggcaa agcagatgtc tttaaaagaa gatataatac
    69061 tactatgtgg tcattatgaa ggaatagatg agagaatcat tgatttaata gttactgatg
    69121 aaatttcaat tggagattat gtattaactg ggggagagct cccagcactt ataatgatag
    69181 attctatatc gagattaata ccaggtgtat taaaccaaga agaatcattt gaagaagaat
    69241 catttaaaga caacttattg gaatatcctc attacactag acctagagat tttgaaggat
    69301 taaaagtacc agaagtgctt ttatcaggga atcataagaa gatagatgag tggagaagag
    69361 aagaatctat aaggataacc aaagaaagac gatttgattt atataaaaag tctaatgaaa
    69421 aataaaaata taatgaaaaa ttaatatata tgtatacaat aaagtaccta taaatggaat
    69481 taaaaacata aaagtgcttg taataactat tgaagtatag tataatataa aatgttgaaa
    69541 atacgggcgt tcctctgttt acactggtcg ggtagttaag aacgtctatg atatctagga
    69601 ggaagaaaga tgaatgaaat gctaagagca attgagcaag aacaattaaa aaatgaagtt
    69661 cctaattttg gacctgggga cacagttaaa gtacacgtta gaattataga aggaaaaaga
    69721 gaaagaatac aagtattcga aggtgtagta ttaaagagac aaggtggagg agcaagagaa
    69781 actttcacag ttagaaaaat gtctttcaat gttggtgtag aaagaacttt cccagttcac
    69841 tctccaaaaa tagaaaaaat agaagttact agaaaaggta aagtaagaag agctaaacta
    69901 aactacttaa gaggtagagt aggtaaagct gctaagataa aagaagctag aaataaataa
    69961 ttaaaaactt tacttataaa tggggggctg atttatcagt cctctttcta ttttaatgaa
    70021 aattacagca aataattata ttagaaataa atagaaatat ttgttgaaaa tatacattat
    70081 ttatctatga atttatagct tttaaaatga aaaataaaat tggtaaatat tgcattatat
    70141 tttgtaacga tattaaaaat aagagaacag tattatgtaa agtatgacgt taaaaagatg
    70201 acaatattat agtttgttaa gatagatttt ttaagtggaa ttaggatata ataatataat
    70261 attaataagg agtgatacat gtgtcaaatg aatacgaaga gtatcttatg aatgacaatc
    70321 tacatataaa ctggtatcca ggtcatatga aaaaaactaa ggagttagta aaaaataact
    70381 taaaattgat tgatgtagta attgaacttt tggatgctag aatcccgttt agtagtaaaa
    70441 atccagacat agacaggctt gtaggagata agccaagagt tgtcgtactt aataagagtg
    70501 atatggcaga tagggataaa ttgaatcaat ggattgaata ctataagaaa attaatatca
    70561 aagctatacc agtagataca ataaaaggcg ttggtataaa taagataatc gaagaatgta
    70621 aaaatgtaac tagagaaaaa atgagttctt taaaagacaa agggagaaaa gaaagagcta
    70681 tacgaataat gatagttgga gttccaaacg ttggtaaatc gtctcttata aacaaattaa
    70741 caggtagaaa aagcactcaa actggagata agccaggagt aacgaaaggg aaacaatggg
    70801 ttagattaaa gggaaatctt gaacttttag atacacctgg aatactttgg cctaagtttg
    70861 aagaccaaga agttgcatta aatttagcat ttagtagagc tataaaggat gagattttag
    70921 atactgaaac tttggcttta agacttatag aaaaacttat gaaaatagaa cctgagaagt
    70981 tgaaagccag atataagtta gattgtctag gagaaactcc aattgaaact atggatatga
    71041 ttggccataa aagagggttt ataacaggta aaaaagaact agattataca cgcatagcca
    71101 caactgtatt aaatgaattt agagatggaa aaataggaaa tataacattg gaagttccag
    71161 aaaacgttaa aagatagatt ttaaaacaaa atcaaagatt taatgttaaa aatttaaaaa
    71221 agccttttag caaaggcttt tttatttttt tgaaatatag acaaatatct ccatataaaa
    71281 gtataaatta ggttagaaaa cctttaaaaa tattaattta agacaaatat acctaatatt
    71341 ttgaaaatta aaatgagtgt gattatttaa aattttagca tattgacttg cttgtttcgt
    71401 ataatatata ataagcacaa ataaatacaa tatattaaaa atttaattta tttaatttta
    71461 ttaatttaat aataagttct tattgtttaa ttcaacttac ttatgcaagc gtaaacaatc
    71521 gagacatttt attaatttaa taaggttaaa aagggggatt ttataatggg taagaccaag
    71581 gatgttatag tatttggatt tgcgttattt gcaatgttct ttggagcagg taacttaata
    71641 tttccacctt acttgggaat aattacaggt ccagaatggt taattgcctt cttaggattt
    71701 acgtttgctg atgctggatt ggcacttcta gcagtaatgg ctacagctaa attcgatgga
    71761 aacgtagttg aaatgtttaa aagatgtggt atgaagttag gaattcttat aggttgtgca
    71821 gatattttat gtataggacc attcttagct ataccaagaa caggtgcaac aacttatgaa
    71881 atgggtataa tgcctttgtt tggaacttca attccagtgt tattattctg tatacttttt
    71941 tttgcgattt catatgtact aacaataaga ccttctaagg tcgtagatat agttggacag
    72001 tttttaactc cagctcttct aatagcttta gcatttataa ttataaaagg tattatatca
    72061 cctcttggag atatagtaga taaacctatg atacctaatg tatttgcaga aggtataggt
    72121 caaggatatc agacaatgga tgcttttgca gcaatagcac ttgcatcagt gctaatagta
    72181 tctttaaatg ataaaggata ttctactatt agtgacaagt tgaaaatgat tggtaaggcg
    72241 ggtgttcttg cttgtggagg attagctcta gtttatggag gattatgttt ccttggggca
    72301 actgtatcaa caatgtatgg aacagatgca gtacaatcac aagtaatagt aaatataact
    72361 gaaggattgc ttggaaatgt tgggaaagcg attttagcag tagtagtatc attagcatgt
    72421 ttaactacat ctataggtct tacatctgcc acaggtcaat atttctctag acttacaaaa
    72481 ggtaaattga gttatgaaaa aatagtatta gctgtatctg tattcagtgc agtagtagca
    72541 tcttttggtg ttggaactat aataaagata gcatctccta tactaagtat agtttatcca
    72601 ccatcaattg ttttaataat tttagctttc ttcaatgaaa aaattaagaa tgataatgta
    72661 tacaaaggag cagtatatat gtcattgctt gtaagtatac taacagttat atctagttat
    72721 ggagtagctg ttccagtagt aaattcttta cctcttaatt cattaggatt taactgggtg
    72781 gtgccagtta taatagctgg aataattggt aattttatac catcaaagag tcaatctaat
    72841 acacttggaa caaactaagt tttgtttaat taaaatataa tcaattgtaa ataaatgagt
    72901 taactaaaag taaaaggagt tatttgtaca aataactcct tttattttta gattctatat
    72961 ttaattattt gtatt
//
LOCUS       DAEPXW010000006        65295 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.006, whole genome shotgun sequence.
ACCESSION   DAEPXW010000006 DAEPXW010000000
VERSION     DAEPXW010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 65295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65295
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.006"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(<1..583)
                     /locus_tag="KRM55_000376"
     CDS             complement(<1..583)
                     /locus_tag="KRM55_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1592649.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIIASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIM"
     gene            complement(580..1425)
                     /locus_tag="KRM55_000377"
     CDS             complement(580..1425)
                     /locus_tag="KRM55_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1592650.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            complement(1539..2129)
                     /locus_tag="KRM55_000378"
     CDS             complement(1539..2129)
                     /locus_tag="KRM55_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1592651.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            2418..2651
                     /locus_tag="KRM55_000379"
     CDS             2418..2651
                     /locus_tag="KRM55_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBH1592652.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            complement(2882..5269)
                     /locus_tag="KRM55_000380"
     CDS             complement(2882..5269)
                     /locus_tag="KRM55_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBH1592653.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKTNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(5461..6216)
                     /locus_tag="KRM55_000381"
     CDS             complement(5461..6216)
                     /locus_tag="KRM55_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBH1592654.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNNNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            complement(6241..7392)
                     /locus_tag="KRM55_000382"
     CDS             complement(6241..7392)
                     /locus_tag="KRM55_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH1592655.1"
                     /translation="MTNLPKQFDSFSEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            complement(7608..8348)
                     /locus_tag="KRM55_000383"
     CDS             complement(7608..8348)
                     /locus_tag="KRM55_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBH1592656.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            complement(8420..9409)
                     /locus_tag="KRM55_000384"
     CDS             complement(8420..9409)
                     /locus_tag="KRM55_000384"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBH1592657.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            9669..10922
                     /locus_tag="KRM55_000385"
     CDS             9669..10922
                     /locus_tag="KRM55_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBH1592658.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            11019..11243
                     /locus_tag="KRM55_000386"
     CDS             11019..11243
                     /locus_tag="KRM55_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1592659.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(11897..12382)
                     /locus_tag="KRM55_000387"
     CDS             complement(11897..12382)
                     /locus_tag="KRM55_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592660.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(12421..13779)
                     /locus_tag="KRM55_000388"
     CDS             complement(12421..13779)
                     /locus_tag="KRM55_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1592661.1"
                     /translation="MINLFSSDLFLKYSFFFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            complement(13781..14512)
                     /locus_tag="KRM55_000389"
     CDS             complement(13781..14512)
                     /locus_tag="KRM55_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1592662.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            complement(14790..16097)
                     /gene="grdB"
                     /locus_tag="KRM55_000390"
     CDS             complement(14790..16097)
                     /gene="grdB"
                     /locus_tag="KRM55_000390"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(15048..15050),aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH1592663.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            complement(16183..17469)
                     /locus_tag="KRM55_000391"
     CDS             complement(16183..17469)
                     /locus_tag="KRM55_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH1592664.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            complement(17748..19070)
                     /locus_tag="KRM55_000392"
     CDS             complement(17748..19070)
                     /locus_tag="KRM55_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH1592665.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNLEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSMSPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            complement(19070..21064)
                     /locus_tag="KRM55_000393"
     CDS             complement(19070..21064)
                     /locus_tag="KRM55_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1592666.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNTYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPFRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            complement(21151..22398)
                     /locus_tag="KRM55_000394"
     CDS             complement(21151..22398)
                     /locus_tag="KRM55_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1592667.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMIANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            22626..23171
                     /locus_tag="KRM55_000395"
     CDS             22626..23171
                     /locus_tag="KRM55_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1592668.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            23185..23871
                     /locus_tag="KRM55_000396"
     CDS             23185..23871
                     /locus_tag="KRM55_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBH1592669.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(23995..24615)
                     /locus_tag="KRM55_000397"
     CDS             complement(23995..24615)
                     /locus_tag="KRM55_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592670.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGIALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(24605..25627)
                     /locus_tag="KRM55_000398"
     CDS             complement(24605..25627)
                     /locus_tag="KRM55_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HBH1592671.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLDTLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            complement(25628..26266)
                     /locus_tag="KRM55_000399"
     CDS             complement(25628..26266)
                     /locus_tag="KRM55_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH1592672.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            complement(26384..27535)
                     /locus_tag="KRM55_000400"
     CDS             complement(26384..27535)
                     /locus_tag="KRM55_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1592673.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLESLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYADFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            27957..28769
                     /locus_tag="KRM55_000401"
     CDS             27957..28769
                     /locus_tag="KRM55_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBH1592674.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(28858..29049)
                     /locus_tag="KRM55_000402"
     CDS             complement(28858..29049)
                     /locus_tag="KRM55_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592675.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            29320..29559
                     /locus_tag="KRM55_000403"
     CDS             29320..29559
                     /locus_tag="KRM55_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1592676.1"
                     /translation="MNYNLIKVIFSLFKKKSGYTFTNFLNKVRVEKSKKYILKKNLSI
                     LDVAVLIGFNSQNYYSIIFKKFNNFTPIEYKNIYN"
     gene            29868..31487
                     /locus_tag="KRM55_000404"
     CDS             29868..31487
                     /locus_tag="KRM55_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH1592677.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            31861..32055
                     /locus_tag="KRM55_000405"
     CDS             31861..32055
                     /locus_tag="KRM55_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1592678.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(32614..32937)
                     /locus_tag="KRM55_000406"
     CDS             complement(32614..32937)
                     /locus_tag="KRM55_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592679.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     TDYII"
     gene            complement(32982..33236)
                     /locus_tag="KRM55_000407"
     CDS             complement(32982..33236)
                     /locus_tag="KRM55_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592680.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            33663..36707
                     /locus_tag="KRM55_000408"
     CDS             33663..36707
                     /locus_tag="KRM55_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1592681.1"
                     /translation="MKKMLKRLCTGFLALATVVTTLPTTPVHAESKQYWTESKERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFRNGYKTRIDASTRMSADQISDVA
                     LSIEYVKQYTDSHSGISNNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFSGARAFVKENKGRYECGGYIYSGEGQELGQFWAKLNIGNAKLKKATSNTSITDGNG
                     NYSIAGATYGVFSDKNCTKQLATLTTDENGNTDVVEVKAGTVYIKELSAPAGYKVDKT
                     IYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGSTHYITKFADAYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKAPNGYLLDGAYMQAGDKSEQIKDLYLTQITEDGDLAVLSGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNAVLVEGKLYKKNEVVKTIR
                     TDIEGIASTSADLLPYGNFRIVESEAPDGYLTDGAKPIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGENHIVVTDDNGQFSTSSEWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLNGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFVADDEEMKVEISYIFNASALGGKNLVTFEELYD
                     FSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKEVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKKENAELLINGKRVESDYTFTADSETMKVEVAFTLDATSL
                     DGKQLVTFEELYDLSNPDDPKKVTEHKDIEDKGQTITFKEKPKEPEKPETPPTPEKPN
                     RPSDSPKTGDNTNLYGLLALLLTSGAGLAGIFFYKRRKMKKS"
     gene            36942..37268
                     /locus_tag="KRM55_000409"
     CDS             36942..37268
                     /locus_tag="KRM55_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1592682.1"
                     /translation="MEMKYVVPDMVQSFGTLEFAGESEPVFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKKFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            37284..37667
                     /locus_tag="KRM55_000410"
     CDS             37284..37667
                     /locus_tag="KRM55_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1592683.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNVGSPQNHTPQGQPKK"
     gene            37754..38239
                     /locus_tag="KRM55_000411"
     CDS             37754..38239
                     /locus_tag="KRM55_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592684.1"
                     /translation="MIRAIIFAVFVVPIISLVLDKTQKATKKEKFTNTVFVSHAYQTV
                     CHICSLIMVGIAIALGLFMGFDNTVGHSVVFAIFVLLIEFCAWALKRHKVVIDGNNLR
                     ITPAVGRTREISFNDISRCTEKEQIGLKIFVGNKKICTVSCDCVGYKEFLEMLKEKNL
                     L"
     gene            38331..39722
                     /locus_tag="KRM55_000412"
     CDS             38331..39722
                     /locus_tag="KRM55_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1592685.1"
                     /translation="MQKIFNKGHRIRASDKHLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     RTDWEHFSLLENGLTLSPYNFITILIATGVCALVVFLYYHFCYDSFKKLLHRQKLARM
                     VLENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLKLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKQHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDMGTSVISEFYTPLVPKGHDFLQTIGRLAQERQ
                     VMPEQQGKEDVIE"
     gene            39817..40206
                     /locus_tag="KRM55_000413"
     CDS             39817..40206
                     /locus_tag="KRM55_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592686.1"
                     /translation="MLDCFLDYSVNPNLRFHSRIDKIIDDVIREKINIPHKFRMRLES
                     RHCVESRIIYFRFRVLDKACLQCNVFLKGLSEEMKEALSDERIDFAVIYEGIQGSQQD
                     TDTDDKDGFCGSQPQVPFLADGACPVR"
     gene            40356..41552
                     /locus_tag="KRM55_000414"
     CDS             40356..41552
                     /locus_tag="KRM55_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1592687.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LVDGGVMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNEWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEQQAKLTEKHKMIIKQQTTPA
                     KDLVES"
     gene            41565..41699
                     /locus_tag="KRM55_000415"
     CDS             41565..41699
                     /locus_tag="KRM55_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH1592688.1"
                     /translation="MWVLLKDFLLVSMGMGIGVVLMCILNVGKEADYEMKQLEESEDN
                     "
     gene            41700..41921
                     /locus_tag="KRM55_000416"
     CDS             41700..41921
                     /locus_tag="KRM55_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592689.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            41992..42618
                     /locus_tag="KRM55_000417"
     CDS             41992..42618
                     /locus_tag="KRM55_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1592690.1"
                     /translation="MKYIMLHGLGQSSESWSDTVKVFNDDFEVLCPNLSDWLFGKIPC
                     YDTLYRTLETYCEQFEEPLNICGLSLGGILAMQYAIEHPEKMNSLVLIGTQYEMPKYL
                     LKMQNLIFRIMPCSAFEKMGFQKTDFINLCKSMTELNFKHELKKISCSVLVVCGDKDK
                     INKKASLELQQQIENAEIAIIENAGHEVNTDNPTLLGQKLNVFFKQYV"
     gene            42707..43003
                     /locus_tag="KRM55_000418"
     CDS             42707..43003
                     /locus_tag="KRM55_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1592691.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEERQL
                     EDFSKYVFGISYQNLKDVMNQQKGREEQCRKQGYWWKREEQLTKKQYHTGSTCR"
     gene            42922..43425
                     /locus_tag="KRM55_000419"
     CDS             42922..43425
                     /locus_tag="KRM55_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1592692.1"
                     /translation="MQETRVLVETRGTTDEETISYWFDLPIDVAEFEEKLGIGAESGD
                     YCIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSSDMQEEYVSLLTVYDNLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            43443..43946
                     /locus_tag="KRM55_000420"
     CDS             43443..43946
                     /locus_tag="KRM55_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1592693.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIAIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIETSR
                     GMCEIPY"
     gene            44055..44453
                     /locus_tag="KRM55_000421"
     CDS             44055..44453
                     /locus_tag="KRM55_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1592694.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDIPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            44431..46881
                     /locus_tag="KRM55_000422"
     CDS             44431..46881
                     /locus_tag="KRM55_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1592695.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELVPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLKEVAYQKIDEQTEALVSMI
                     GNNQVDYRFFLGFKLMVKEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYAYQLPKKKLNKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGGETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKAERGNWRE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSDSRGLLHVIDELRREDTPISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVAKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            46881..49070
                     /locus_tag="KRM55_000423"
     CDS             46881..49070
                     /locus_tag="KRM55_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1592696.1"
                     /translation="MKERIKGAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTQNGFSSTGFYIGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQNMGRRIFRRP
                     YLFMRHRARRMERRLAGAVTAGGVAGAVAGSTISNRKPTRNTATKDSRGNTSTSSMGQ
                     RAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKRGMVQ
                     EQQSRQTGRLEKQEKHRQSIADKRMELQKAQEARQAQRKADGSATTGATRPHERPATA
                     SKPSAEKMQEVKRPATATTSKASEPVKTNVIKERPLSSGASDKKATQSAQPVHRQNVE
                     KVVSQETRQNYTKDRRTKVQQTQTVQKNQQTTEKTRNLVMKKGQKKK"
     gene            49067..50074
                     /locus_tag="KRM55_000424"
     CDS             49067..50074
                     /locus_tag="KRM55_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1592697.1"
                     /translation="MKLKHIAIIGTLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAREYGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYQYGNQFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKAGVSLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGILVSPTQMYHAGNPIGYADLNNSYWQQHLIGAGRVK
                     Q"
     gene            50092..50994
                     /locus_tag="KRM55_000425"
     CDS             50092..50994
                     /locus_tag="KRM55_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1592698.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEIIELRLQDTNGIENFVKNFAKSYYTWSNNKEAIEARTQAISG
                     YLTKELQDLNVDTIRTDIPTSSTVTDVIVWHIEQSGTDTFSATYEVDQQIKEGEQTSN
                     VKATYTVKVHVDADGDMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTVNDATAFLE
                     TFFKLYPTATEKELAYYVSGNVIEPIGRDYLYSELVNPIFTKDGDNVKVKVAVKFLDN
                     QTKATQVSQYELVLHKDSNWKIVG"
     gene            complement(51041..51598)
                     /locus_tag="KRM55_000426"
     CDS             complement(51041..51598)
                     /locus_tag="KRM55_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005946872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1592699.1"
                     /translation="MKTTKEAVIKATSDLADEKGLNNVSLKAVAQKLNIRTPSLYNHI
                     ESLDNLLLEVAHNGMRDMNERMMKIAVGKIGKEAIKLVSIEYLNYMIEHPGVYETIQW
                     AVWHGTEETATIFNNYLSLLTTLIQSCSLNKDKTLEILNMLTGIIHGYTTLQLGNAFS
                     ASDKVRFELAEAIDTLLVGIFQKYK"
     gene            51778..51861
                     /locus_tag="KRM55_000427"
     CDS             51778..51861
                     /locus_tag="KRM55_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBH1592700.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            51986..52723
                     /gene="erm(B)"
                     /locus_tag="KRM55_000428"
     CDS             51986..52723
                     /gene="erm(B)"
                     /locus_tag="KRM55_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBH1592701.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            52869..53153
                     /locus_tag="KRM55_000429"
     CDS             52869..53153
                     /locus_tag="KRM55_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBH1592702.1"
                     /translation="MPTKRSGPLVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFR
                     KKKLTKTNVKELLEGKETLVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            53305..53583
                     /locus_tag="KRM55_000430"
     CDS             53305..53583
                     /locus_tag="KRM55_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1592703.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETEQVTLELEMEEEKSNDFV"
     gene            53964..54854
                     /locus_tag="KRM55_000431"
                     /pseudo
     CDS             53964..54854
                     /locus_tag="KRM55_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
     gene            54925..55620
                     /locus_tag="KRM55_000432"
     CDS             54925..55620
                     /locus_tag="KRM55_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1592704.1"
                     /translation="MCTRFVYNGIDKIVGFNFDIDLSVWDHTVITEENRFYIGIKMPD
                     GLYHSFHGINKNGNVGTLLYVHGNENARYIESEDCITISELTEKFIKAEISFDKALDI
                     VKKKKIIYAPDATMQAMLSDKKGRVLIIEPGIGYRYEQENFSLITNYSILKPDITKPY
                     IVSGDTRYEVAKELLAGYDKDFSVNDAFKVLKSVSQKDLWATRVSFVYSTEKNKVYYV
                     LNNDFSNVFEFQF"
     gene            55666..55890
                     /locus_tag="KRM55_000433"
                     /pseudo
     CDS             55666..55890
                     /locus_tag="KRM55_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(55936..57228)
                     /locus_tag="KRM55_000434"
     CDS             complement(55936..57228)
                     /locus_tag="KRM55_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1592705.1"
                     /translation="MLNNLYRKLHILFASSVMLIITLVISFVVANTVHTEKINESTLF
                     QRLTTLLIYQVESASSDMDKALKTYEESYHIFSLITDTRGNTIYQSDFPFPTSADNLL
                     HDVEKQISTQPLSQIENSTTSQGGFLEIRGTHHDTYFVIPATIRTANDTVYHATFLYQ
                     TASLTDILQKTLPIYLLIWFLACIVVIVLTRYLLKKSFAPTERILQSQKDFVATASHE
                     LKSPLAVMISNTDMLLDNVSLNEQAKQAVQTIDFECMRLSRLVKDMLLLASSDAKTWT
                     LHKSTINVDTLLITLYETYEPVCMKQNLELKLHLSEESYPAMFTDKDRLFQILCVFMD
                     NAIQHSKNNSLIEIEVIATEKNIAFSVVDHGQGISDEDKQYIFDRFYSGDKSHTNKSN
                     FGLGLSIAKELTQMLNGIIIINDTAGGGATFTVKFPLK"
     gene            complement(57222..57908)
                     /locus_tag="KRM55_000435"
     CDS             complement(57222..57908)
                     /locus_tag="KRM55_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1592706.1"
                     /translation="MKILLLEDDLELCKNIKISLEKENYMVDCCNDGETAMLYALNTD
                     YAYDLAIVDRMLPIIDGLTIIKSMRKKGISIPILIITAMSTLDNRVEGLDGGADDYLV
                     KPFHIKELLARVRALTRRPANIQLSSKLEYGDLTFDKDSRTLSTPVNSLLLTSKETEL
                     TFVFMQNPETLFSREQLILKIWGSSSEVETGNVDSYISFLRKRLKELKSSCKITTVYG
                     AGYKLEKETC"
     gene            58102..58596
                     /locus_tag="KRM55_000436"
     CDS             58102..58596
                     /locus_tag="KRM55_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
                     /protein_id="HBH1592707.1"
                     /translation="MKKTNISKFVAVGLCICALTGCGASPDEKPDMSNPIVNSNTNEE
                     NANGSSENKENDILESANLIGSVLEFTDNGCSVSQAKEIEGGAGIKSEAPGLENKDNA
                     VSVTYNPDCEFVIATVNAQSGVTNVTTGSISDVKKQSEVYLYGEFADTLHFNATKVVI
                     ARWE"
     gene            58608..59831
                     /locus_tag="KRM55_000437"
     CDS             58608..59831
                     /locus_tag="KRM55_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1592708.1"
                     /translation="MKFYQLGFRYLQRKKGKTILLLIVLILVNSMILGTSMILRTTNE
                     SKQAMQEKTNSKIVAEITSKDSKITENEVNKIETLEDVSAINRIGRQDVFPASFAPVT
                     LNTSTNEENLKIALLSYDDLEKDSPFSEMQYRLASGDYIKREKKGAVINANLANQNEL
                     KVGDTIELSTENGTKVSVQIIGIFMSAGNAEKDQPSETTAVNRIENQIFIDNSTYKEL
                     FKEAEFEKICIYSKRPEKLDVLETSLQKIFGNDVALSTSDTLYQQMSAPLEQISKVAN
                     LMLVLTLVTGTVVVSLLLCMWMRTRQKEVAIFMSLGKTKSEIFLQTLLEAGSVFTLSV
                     LGATAIGKLFSGVLQNVITGSETVTENLKVVLQIQDIGMLFLLGGAVILVALCCSILP
                     ILRANPKDILAKMEG"
     gene            59835..61280
                     /locus_tag="KRM55_000438"
     CDS             59835..61280
                     /locus_tag="KRM55_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1592709.1"
                     /translation="MNFFGLARRSVFRKPVKSILLLLIVFAISTLLLAGVASKNASIE
                     VQDKTRQAIGAGFLLERNAEYRTKRVREYSEKIGNDKEGSFGGYHQEKEIINGVETWT
                     GWTTNEFESLDIKDIEKLAKAKGIADYNITTVTTPVNPVNFKRIEDKDVDQNADVGGV
                     SLIGNKDMKLDRNVLSGNLHIKEGRMITPEDKDMCVISEELAKQNNLKIGDKISFNDY
                     HDTENSKVSEAEIVGIYQVDQKMSPLMQGDTYRSENVIFTDLRFPEKAEGETSPLYER
                     AYFKVEDVEAYDEVKENLQKVDINWEQYDLIDNNGNSETMSSNFNDLAKVSEMMILVI
                     SVASFVILVLVFLFWLKNRVQEVGIFLSLGVPKFRIIGQIWSEAIMITVLSLMLSFAV
                     APAVSKVTANYLVSQQVQQMQEEEKNNEGKVSTEYVAPKQDVQSISVEVTPEMYLLDG
                     VSVLVLITASVLVSGIVILKRNPKDILSEMS"
     gene            61294..61929
                     /locus_tag="KRM55_000439"
     CDS             61294..61929
                     /locus_tag="KRM55_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1592710.1"
                     /translation="MLEVKNVSYAYKTKKDKTILNNVSATFEEGIFYTIIGPSGAGKT
                     TLLSLLAGLDTAVKGTVLCNGEDITKKGLNYHRKHNISLVFQNYNLIDYLTTVENVKL
                     GGSGNAEKLLEEVGIGKEYWQRNVLQLSGGQQQRVAIARALASDAHVLLADEPTGNLD
                     ETTADEIIALLKKTAHELGKCVVVVTHSKHLAEEADEILEIKNGAISFLSE"
     gene            62204..62644
                     /locus_tag="KRM55_000440"
     CDS             62204..62644
                     /locus_tag="KRM55_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592711.1"
                     /translation="MKPSELQEKTCHQFDCAIKTVIRHRAIDFYRAIRRSEKKEMPFA
                     EIMDDLLNSIGTEDTYSTDYVAVFEVCGEKVSIEDEQLARALKAIEERKRNIVLQYFF
                     IGDTDTYIGKMLDCSRANVTKCRIQALDKLKQLIEEEKEKCQKS"
     gene            62629..62862
                     /locus_tag="KRM55_000441"
     CDS             62629..62862
                     /locus_tag="KRM55_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1592712.1"
                     /translation="MPKELTPTFTVISKACDGDETAISKILEFYDPFINQCCMRPFYD
                     DNNNLRLAVDLEMKGFIKEAIIRKILNFDIKRF"
     gene            63176..63379
                     /locus_tag="KRM55_000442"
     CDS             63176..63379
                     /locus_tag="KRM55_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1592713.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENIDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            63458..64648
                     /locus_tag="KRM55_000443"
     CDS             63458..64648
                     /locus_tag="KRM55_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1592714.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYSWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLNDGIDTVGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSEKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFDFKLSDVLEDDTEQKVILTPEQEERLLAFMEKDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLKDSEMGYYIETPKTKNGKRELPLTE
                     RAYQAIQRILKNRGKAQPLIVGGYSNFLFLNREGLPKVAGNYEGMVRGLIKKYNKYHT
                     DKLPNITPHSFRHTYCTNMANRGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(64953..65234)
                     /locus_tag="KRM55_000444"
     CDS             complement(64953..65234)
                     /locus_tag="KRM55_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592715.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT        21859 a        10964 c        10433 g        22039 t
ORIGIN      
        1 tcattataaa atttttatct ccactaataa gagaaataca tatattaaaa gggtacaaat
       61 ttgcatatga ttttgtgtca agaagtacat tcagtattgg tggaataaag catataatct
      121 caataggaat acttaaaaca ataaactgat tcaaactaga tgctttactt gcaattatca
      181 atccaagcaa agaaaatata atagaagaaa aaaaggtacc tatagttgat attataatat
      241 tatctaaatt taatgtaata gcaataaaca tagctacaat actagatatt actcctaatg
      301 aaattacctt tgataaaata tactcagata cttttactgg agatacagct aaggaattta
      361 aaaccctttg acttttctca agaagtacaa tagctcccat aaaaaacaat cccattgctg
      421 ctgggtcaga ataaatcata attatagcta ttttttctct cataaaagtt ggaaatacat
      481 tgataataca aatatatata atacttaaaa aaagatataa aaaataaaaa ccatacttaa
      541 attgaaactt tatatctcct aaaataagat tttttagcct cattgtaaat tcctccctgt
      601 tatctcaata aaaatatcat ttaatgttgg ttcactacta tgtattgata aaagtttatt
      661 tttctcaata agcatattca aatttttatc attagcagta ttgttcagaa aacattcaga
      721 agttttttct ccattatcaa agtaagtata tctaacttta atagctcctt ttgacataat
      781 aagattatgt ggtgtatcta aagcagatat tttaccattt acaatgaacg ctactctgtc
      841 acaaagctct gttgcatcta acatgttatg agttgttaaa ataatagttt tacctttaga
      901 tttttctgat aaaattatat ctttcataac cttgctattt gatgggtcaa gaccacttgt
      961 tggttcatct aaaaataaaa tatctggatt atgtaataaa gcttttataa aatttaatcg
     1021 agatttcata ccttttgaat actcagatac ccttttattt gcttcatttt ctagtcctac
     1081 tgattttaat aactcatcaa tagatagtag ttttttagaa tatagagacc caaaatattt
     1141 taaattttct attgcagtca acttttcata taaactagga aattcaaaat caactcctat
     1201 attttcataa aatttatttg agtgtctttt actctctact ccatttacaa tgacacttcc
     1261 tccataatta gttatcattc caattagaat cttttgtaat gtagattttc ctgcacctga
     1321 tggtcctaaa aatcctagta tttccccttt tcctacttca aagttaatat tttgtaaaaa
     1381 atctctatct gtataactaa atgataaatc atcaacttta atcattcaat atcacccttt
     1441 caaatttttg actattttga ctatatggtc aataaaatat aatttttttg tttgttaata
     1501 atttttaata aaagttatta gcaaacaaaa tttaaattct attccataag ttgtataact
     1561 aatccgttta tcattaatct caaagcatct tcaaaacaat tacttccaac ctcgcgctta
     1621 tatagcatgg taagaaaaac tgctctaaat gctccactaa agctttctat gtctttattt
     1681 tttgcatttg gtatgcaaga tataatctct ccaatttcaa agtcatcatg tctaaagtgt
     1741 tcttcaatta tagaatctgg taactttctc accaatatct caaattctcc atttatcatg
     1801 agatttaaaa ttgaagtact atcaaccatc ctatagaatt tcataaatat atctgtcaat
     1861 tgttcacatg taatactttc atctactcta tttatctcat ataagatttc tttttgtata
     1921 gagtcatgta tatctcttaa tacctcaaaa aagagcaatt cttttgattg aaaaaataga
     1981 taaaaagttc cttttggtat ttttacccgt tttacaagct catcaacagt agtttttcta
     2041 ataccatatt gctccataca caatcttgct tcttctttaa gtctttttat tatatactct
     2101 ctttctttat cagaatatga tttaggcatc ttttccctcc agtttgacta aaataattta
     2161 tatagtcaat ataatacttt ttctatctaa tgtcaatagt attattagta tatttaaaaa
     2221 taagcttaaa aactttcgaa aattctgaat tttatatagc attttttatt atctagtgtt
     2281 ataattaaga tataaataat atattattct aattttcata tctatttgct tattttttaa
     2341 cttagtttct aatagaagta atcatattta tctttttaaa agtttcaact ttaataaaaa
     2401 ataaaggagt tgattttatg gctactacta caaaaaaccg tttttacgat tatgttcaag
     2461 aaaacttaaa taaatatgtt gaagtacatt cttactttag cagttgtcct ctatatggtg
     2521 aaattataga agcagatagc ttatcaatta cactttgctc aagatatata gatgaatcta
     2581 atccaacttt aaatgaaact tacacattat atttaccatt aagttcaata atatctatta
     2641 gaacactata aaaagttaat taaatatggg ttatttatat ataaaatgta agattttcta
     2701 tatttctata taaagtaacc cttttttatg tttttaaact tatactacat aaatttaaag
     2761 ctgaaaacaa aactttacaa tcattgatta tcttatttat caataattta aagtaattat
     2821 tttcagcttt tattaagata agttactaat acacactaat atatgttaat acttaagtac
     2881 tctatttagc actttttaat tttactaact ctttaaatgc atttttattt gctcctccac
     2941 caacttgagt tactttttct aaagtcttat ttttaagaac ttctttttgg ctatcagcta
     3001 atttatcacc aactaaaatt actggtgacc cagtttttgc tcctaaagga ccaactgcca
     3061 atccatctat taaatcattt tgattcttga ttccattttt aactacaaat gcatttttta
     3121 aagtatcttt tttataaaaa ttatctatta tctttgaatt agtttcgtct ctactactac
     3181 cagataatct agttggattt tttaacttac tttctagatt gtttgatagg gatgctgttc
     3241 ctccaataat ataagatttc tctatattta atgaatttag aaattcatca gctccttgca
     3301 attcgctctt ttcatttgca agtatgattg gtatgttatt ttctgctgct gcagcgccta
     3361 cactaattgc atcagctaat cctttcactc catttacaac tgctatttga gatacatttt
     3421 ttataccatt taacttttga gctaataata aacttgtctt gtatctatca cttcctgata
     3481 ttctctctat cgatatattt aagcttttta attgttgttc aatttcttta cttatagaat
     3541 tttctccacc tattaggtat actttcttag cacctaatct ctgtatctca gctttagttt
     3601 ttgaatttaa agcttctttt tgtgtcaata atattggtga atttatagca gatgtaaaag
     3661 gagttgctgc caatgcatct actattgaac tgccatttac taaaactaca ttttctgaag
     3721 aattgaaacc attttgacta actttgatag cagtttcata tctatcacta ccaattaaag
     3781 actcatttgg gatactctca ccagaagact tttctgtaac agcttttata gtaaaattac
     3841 acggatagaa gttactatct ctatttatat caaagaattt tccagtatta tctatgatat
     3901 aactttcacc taaattagct tttgctttaa atgtatcata tcctggtaca tttgactcag
     3961 aacctatagt tgactctcca tttttcccct ctatactgac tacaattgca ccctttcctt
     4021 ctggtatatc aaaagaatca attggaactg ttatgtatcc tgaatattgg gcagtacctt
     4081 cttttaattt tttcatattg ttttcttgag gtataccatt tactactgga gcataatata
     4141 cttcatactt agctcctata ctttcagtta agaacattac agattttaga gtttcatcgc
     4201 ctctattgaa atcaaataca tttgcagctg ttatcttttt tgaaattaaa ggtacaatac
     4261 ttgcatagtc atgttgatac atcttctcat catcatttgt ttttttacca cctttgattg
     4321 aaaaattatc tatatcagac ataagtgtct tgtcttcata agatatccag aaatatccac
     4381 cctcagaatt ataatctccc cagctatttt ttattaacca agcaccattt tttgatggtc
     4441 taatatttgc attaaaatta tctttagaat agttatcatc ccaacctaca attgaaatag
     4501 catgatttgt attaaaactt tttgttggac aataatatga attttggtca tcactttgat
     4561 atttaatatc ttcataataa ccagatgtta cagctccata ctgtaatata gcattttttg
     4621 tagaatttat gtcattgctt acacacacag catctgtcac attaaaaaca gtaggtgctg
     4681 tattcatatt agttggtttt tttgctcctt gtgctttaga tactctacca ttgtatggga
     4741 tatctttttc taatttagga cctgaccaag atgttaaata tcccatagct tcataattta
     4801 aagcaccatt catatcattt acagaccatc catattcacc atctgaagcc caccatctta
     4861 agtgttcttc tgataaatca tagtctccat aattatttaa ctttaagaaa ctttctaagg
     4921 ttgccattgc agcaaaatcc caacagattc ctaaatcctc ttgatttttt attgatgtca
     4981 taagacctaa ttttctaggg tcataagatg ttggagctgt tcttccttta ctttggattt
     5041 gagtaccttc caactgatat ggatttggta taatcccatt atatttttct gtacgtccat
     5101 ttttagcatc atttagatat tgtttatacg tctcactgta ttctgctttt tttatctgat
     5161 tcaatgtatt gctattgtca gctgatacag gaattgttga cattactaaa atagatatta
     5221 aaaacagcgc aacaaacctt gttacttttt ttgaagtaaa ttttttcacg ctttctcccc
     5281 cttattttga gctaattttt aaaattataa tgttatatat gactaaatat caagtattta
     5341 caaatataca atcatttaaa tcaattatac caaagttttc ctttataaat aaataaaata
     5401 aaataaaaaa ctgaatttat ttataataaa ttcagcttct cattttcttt ttatatgttt
     5461 ttatctaaat cctattacag cagctcctaa agctcctatt atttgagtat cttctgcaat
     5521 aaaaattttt ttacccagta tttcttctat catttttact agttctttac tttttgcaag
     5581 ccctccagta aatgcaactt catctattac ctcacctctt gctaacattg aggtggattt
     5641 atttgcaata gatttaagta tccctgctgc tacctctcca gtagaaatgt tttgagctag
     5701 aagacttaca atttcagact cagcaaaaac tgtacacata ctagatatat taactggttc
     5761 atatccttta gctaatgtat ctatactttc aatatcgctt cctaaaaggt tagaagtaat
     5821 ctctaaaaat cgaccagttc ctgcggcaca cttatcattc attataaagt taaatacatt
     5881 tccatctcta tctaaattta taactttact atcttgacca cctacatcta aaatagtcct
     5941 tatgttattg tttaaaaagt aaatacctct agtatgacaa gttatttctg ttactttctt
     6001 atcagcaaaa tccattactc cccttccata acctgtacct accacctttt ttatatcttt
     6061 tttgtcaatt tcactactta gcaactcata gacctgttta gatgtacttt tagggctcca
     6121 tccagttggt ataattattt tcttaataat tttttcacca tcaaatagca caccctttgt
     6181 tgccactgac cctgagtcaa ctcctatact aaacatagtt cctcctactt ttatttattc
     6241 ctacaacatc tctacaaacg cttcaaatct agttcttaat tgttcagtat ctgattttga
     6301 ataatcagtt tcaagagaca taaatggctt atttttttct tttgtaacaa attctcttat
     6361 tctataactt tctatattaa atgtatgaca tgcttgtaaa actacatcta ttacagcatc
     6421 tacattatat tcatctatta ttctatctaa taattcaata cgattgtcat tattcatcat
     6481 acaagaacaa cctatattta tatatttttg tgttaaagca tcatatacat cttctatttc
     6541 ttcatcaacc aataaatcgt ttgatctaat agctccacaa agttcatatg caacgactga
     6601 tgcccctgca tcttctaaag ttttaactat tttttcgctt attccaccaa taggagaacc
     6661 tgttatcaat attcttggct tatctttttg aacaggacat tcaccttttt catatctttc
     6721 tttcatatca tctataactt ttcttaaaga atgtttaagt tctgcacggt caaatttaaa
     6781 acctgcttga tataaaacat tatgtaactc caggcctgta agtgcagatg gttgtaattt
     6841 accaagtgca taaaactctt ttaaaagttc tctttcttca tttttatctt ttatagcagt
     6901 tcttatatct tcttcagtta tagttacacc taaagatttc tcaacctctt cttttaatct
     6961 tatcatttca tctttccaaa gtttataggc aaattctcct tttgaagtat ttggcaaatg
     7021 cattacatat gttggcttaa cttttgcaag ttcttcatac atttttttct taccatcaca
     7081 agtggtttct cctatcaaca aatcagaaaa atagaaataa ggacaggtat ctgttattgc
     7141 atgtccatag cttgatttaa ttaaaggaca aagatttctt ggaagcaccc tttctgcatc
     7201 aggtattggc tcttcactaa cgccgcatac acctactaca gttgctccag ctgccattgg
     7261 aatttcaact ggagtaaatg tacagaaaac tccaaccatc tttttcccac tttccttaag
     7321 ttcctttgca tttataaatc ctttttgtct agcttcactg aagctatcaa attgttttgg
     7381 caaatttgtc atgaaaatat tcctcccaat tacttctctt cataattcaa tctcttcgta
     7441 attcaatttg tatcttaagc aataaaaact aaatttttcc attaaaatac aaacctctac
     7501 attagattct atcatgcttt accttttatc cataattgtt tttatcaata caaaattaga
     7561 tacatataga tatattgtat aactaatttt ttatgttata atttttctta taacttaagc
     7621 tctcgaatcc tcaatctata agcagacaca gcagtttcac ataatttatc aattaatttt
     7681 ccattcacat aaaatcctac aaatgctcct attccaggca ttagttgtaa aaacttagct
     7741 aaatctaaat aatccctata ctcttgttga aatgttctcc aatcaaaatc attgatgtct
     7801 tctggtagac tatttacata ttcatcccag ttattcatca atttaaaagt tttgtttata
     7861 tgctgttgac tagaaaaagc caactgtaat atatttaata tataaatcct ttctctataa
     7921 tctttaacat catatccata tattgaagct acatcatata aaaatttcac tttaatacct
     7981 aaaagcaaag gaaaatcaga taaacctaag aggattcctc ctgcccctgt tcctgctcct
     8041 tcaatcattg ctgtggtctt gtaagtttta gctttttcta aaactaattt ttctctttct
     8101 tctaatgaca tatttctaag tggtggcttt gtagcatatt tatatccaaa cagtacggtt
     8161 tttgtcatta cttttataga agaagtaatt atttcatgat atttatctgg caatactcca
     8221 ttaaatttat tctgtatacc ctttgatgct ttgtcaaata tagaaggttt ctttaatata
     8281 tttttcttcc attcttcaag ttcttttttg actagtttaa tataaacaac atcttcataa
     8341 tctttcacat tttttctcct aatacaatgt atttttgtca atttaatagc ttaatttaaa
     8401 gtttaaatat ttttatctat taaattaaac tattcaaata ctctttagtt tctttatctg
     8461 caaaactagc ttctactgca tttctataaa ttattttata gtcttctaat cctagtttaa
     8521 aagtatcaaa tataacattt agttctgaac ttaaatttat atctgataca gttctattat
     8581 cagtatttat acttacatgt aaattatctt tataaaaagt ataaaatgga tgtgcttcat
     8641 aagaatctac tgtcttagtt tgtacattac tagttggaca taattcaagc aatatttttt
     8701 tatctttaac taaattatac gcctttttat ggtctttaat ttttacccca tgaccaatcc
     8761 tatccgcctt taaaatattt atagcatcca atacattttc tccacttgca gcttctcctg
     8821 catgtattgt aactttatat ccatattctc ttgctaattt aaaaacatct ttatattcct
     8881 tacaaaatcc ctctttctct ggaccacaca agtctactgc tacaacacct ttatttacaa
     8941 atgatttccc ttcttcaatt actaataatg cctcttttga ggtcattgtt ctcatacaac
     9001 ctaatattaa attgcctttt atatcataaa tactttcagc ttctctaatt ccttcaatta
     9061 taccctcaat tatattttta acactcatac ctttttgggt gtgaagtaat ggtgcaaatc
     9121 taatttcaat atattttaca ttttctctac ttgcatcttc caaaagttca aaagtaattc
     9181 tttttaaatt ttccttagat tgcattactt ttaagggtaa atcaaatttt tctaaatatt
     9241 catctagtga agtacaatta aaagaaacct ttgctaattt ttttatttca tccatattat
     9301 ttgaaggtaa atctattttc tctttaatag ctatatcaag catggtttct actctaacac
     9361 ttccatctaa gtggcaatgt aaatctatct taggtaaatt ttcaaacatt ttatcctcct
     9421 actgtactta taaataatac tatcaacaga tttttaagtc ttatttctat tatatcaata
     9481 tactacggtt tttaattcta aaaaagtcac atctcattaa aatattttaa tttaatttat
     9541 gattatctaa ttatatctac tgattctttt taatatacat ttattaatat acatttgata
     9601 ataaaatttc aatacataag aatttaagtt atataattaa aactttgaat tacaaaggag
     9661 gacttatttt gattacctta agttttgata tagtgcaaac cttgacacta tctatattct
     9721 tctttttaat tggtaattta ttgaagaata aagttaactt tttaaataat ttctgtatac
     9781 ctgcaccagt aataggaggt ctattatttt gttttctaaa tttatttttt aaatatttta
     9841 atatagcaga tatatctata agtggaaatt taatgccaaa ttttataacc ttctttttta
     9901 caactatagg actcgaaata agcataaatc ttataaagaa agggggtagt gtattattta
     9961 gatattggat tttgtgtgga gtattggcat tttgtcaaaa tatattagct attacaatat
    10021 caaagattat aaaacttgaa cctcttttag ggcttatgtg tggaaatgta tctatggaag
    10081 gtggtcatgg ttattctgct gcatttggac ttacaataga aaatctcggt atagaaggag
    10141 cagttggggt tggattatct gctgcaacaa taggacttat tatgggtggt atattgggat
    10201 gtcctgtagc taaatttcta ataaataaat ataaattaaa accatcatca aatatagact
    10261 tgtcgattcc tagatataat agaaatctaa agagatttgg aagtaaattt tttagaaata
    10321 agaataggat aaaaaataat aacttctccg aaacaataac accatctgta tttttggaac
    10381 aggttcttct catatttatt tgtataaata caggagaaat tataagtaga tgcttctata
    10441 taacgtttaa tatactatta ccctctgttg taacttgtat gttttcggct gttattttta
    10501 gaaatttaaa tgataagata aatatactag aattaaattt taaacttata gattttttaa
    10561 aagaactttc attgggaatt tttttaactt tatcacttat gaatatagat ttatttgaat
    10621 tatctacatt attacctcct attctcttaa tagtaacttt tcaagtaatc tttataatcc
    10681 tattttcaat atttatttgc tttagagtac ttggaaaaga ttttgattct gccatcataa
    10741 taagtggttt gattggacat ggaataggag ctactccgaa cgctttggca aatatgagtt
    10801 ctttgacaca aaaatatggt gattctccaa aagccttttt ggttgtacca ttagtaagtg
    10861 gttttttgct agatgctatt agtatcccat gtatactatt ttttataaac atactaactt
    10921 agtatgttta ttttttgtta tatattgaca atttgctctt tttgttatat attataaata
    10981 taaagtttga taatgatttt cattaggagg tgttaataat gactgtttac aacttaaaac
    11041 ttggacaaaa gggaattata gacaatatag ctggaaatga aaaacttatg aagagacttc
    11101 tagccttagg actaatagat ggcactgaag ttgaagtgaa aaagatagct cctcttaatg
    11161 accctatagt gattagattt agagggtttg acttagctat tagaaaatct gatgcaaaaa
    11221 atataaattt aaaaaataat taatatataa taaaaaagag attttaaatc tattttcagg
    11281 ccatcaacat tctatgtgtt gatggctttt taaattcaat catgttgtaa tacagataat
    11341 caacagttag ataatgtaca gtataaaaaa tttatattaa tttgtgtaga tatagttatg
    11401 ttattgactc atatttactt taatgggcag ttcaaacaaa cgatagaact gtataagcaa
    11461 gcatttaatg ctactgttaa aacattgatt gaagattcag gtcatttgct tattgttcat
    11521 aatgaaatag tcattcataa taagttctta attttaaacg attttggaaa caaaaatggt
    11581 gtttcaatat cagaagggta tcaaccaaca tataaaattc aaacggcttc ttgattttat
    11641 taaatcaaaa agccataagt caacaatcta aaaagagatt ttaaaatctc tttttttgtt
    11701 tatgtataga taaaattgaa taagtattta aacattatat actatgtaaa agttatcaat
    11761 atagacttgt aaataatagt tataaaacca catataaatg tgctaactgt aaataaatat
    11821 gtgggtcttt aaaataaagt gtgtattctt ctaaaaagtg gtgataatta aaatattaac
    11881 tatttttata aataaactat ataggtctat taaattttac ttttaagttt ttatcatctt
    11941 ggagaacacg ataagtatta tcccattgtt cgtctacatt gcttctttca aaaacatcat
    12001 ataattgttt tacattttca ttattagaag gttctttttt tctctctaat agattattat
    12061 ttacttctga aacattattt tcttctttat ttgttttttt tgctttattt ccttttaact
    12121 cttgaatttt attttcaatc tcttccattt ctttttttaa agcttctatt tttaatttgg
    12181 ctgtttcacc atcaatactt ttatcacttc ttactttctc tatttcatcc tgtaatgatt
    12241 ttttcttttg ttctaagcct tgtacctcac tttgacaact atctaaacca tttgtaattg
    12301 gtgcttgacc atttatattt ccaactttca ttttagtaac ctcctcattt ctatatatca
    12361 aactttctct attcaagtac ataatatagc ttacaaatac tattttcaat gaaattgttc
    12421 tcaaatacta gcgcaatgta atgaaataac tagcaataca tttatttgaa aatagtctga
    12481 tgtcttatct atacttatag ccccttgata ttttttagca atttctttta tatttaaaag
    12541 acctatacct gagccacttg tataattatt tattggatta tagctatttt ttatttctat
    12601 cataaaaaat ccaccctcta acttagtgga aagctttaaa tacctatttt gtttatctac
    12661 aactctacaa gctttaattg cattgtcaat agcattagca aacactatac ataggtcaaa
    12721 atcgttcatg ttagtgcttt ggggtataat tacttcacaa tctacctcta tgcctaattg
    12781 ttttgctata cttaatttat tgttgaaaag agcatcaata acaatattct gtgtattaca
    12841 agaaaatgat aggtcacttg ttactttttc aagcttattt aaataatctt gtgcttttaa
    12901 aatttggtct tttttcaaca atccattgac aatagctaaa tgattattaa aatcatgtct
    12961 aaaggatata gtttgtgata atcgtgattt cgcttcttca atatagtttt tttgagcatg
    13021 aatctgttga ttcataattg ccctctcctt gtcatcttcg agagcttgaa ttagtttctt
    13081 aaaggtaaat agagaaaaaa atacacatat agttccaatt atagaaaaaa gaaaagcttg
    13141 aatttcttca gttatagaag tatttaatag cagctttaca atcccaagac ttgtatctat
    13201 atttatattt gaactatatt caaatgattg cataaataat attataagca acaatggaat
    13261 catcaaaatt gctatatatt tatcaaagtt catgacctta atattaaact ttttagaact
    13321 ataccaatat ataaatccag ctattataat agtaattaaa gaagatagtc ccatatttat
    13381 atcaaattta taaatatctg tatttatatc actagtaaat atcaagtaat ttaatggagc
    13441 tgtaaatcca tatactaatt gttcaattaa atatactaac aaagttgata ctatagataa
    13501 aacagtagat tgttttatta tgtactttac aaataaaaaa gtcataagaa aaaatagaat
    13561 ctgtgaagaa aataaattat ataaattaaa atatgtattt ataatgatta aaaaaattga
    13621 aattatcgaa tataaaataa aacaccaaaa ttttgaatta acatttgtaa aactgattag
    13681 aaaatagtat tgcactatta ccattaaaat tctatataca ataaaagaga agaaaaaact
    13741 atactttaaa aataaatcgg aagaaaataa attaatcatc ttatatcctc ctatttttca
    13801 tgaactcaag cataactttt gaaaatattt gttgacgtag tctagaaaca ggtattctat
    13861 ctccactttc cataactgca ttaccatttt catatccata tacatattgt aaattgatta
    13921 tataactacg atgacaccta aaaaaatttg ttggtaaact tctctctaaa ttttcaatag
    13981 tctcataata atctacagtc tctttcttta aatgaacata aatctttctt tttataactt
    14041 cacaatataa aatatcagca agttttaatt tccaatatga ataacctttt tgtattgtga
    14101 tataattact ttcattatca tcaagttttg taactatttt atccaaagtt ttatatagtt
    14161 tctcattaga tagaggtttt atcagataat ttatagcatc tacttcaaaa gcatcaaata
    14221 caaattcatt taaaactgta acgaaaatta taaagcactc attaccatat gaccttaatt
    14281 ttctagctgc ctgcattccg ttaatctctt ccatctgtat atctaaaaat acaatattaa
    14341 acttttcatg attgcatagt aaatcttcta ctttattaaa aagctctata ttatataata
    14401 aattcttctg cttcatgtat aattctatat tttcctttaa atgatttagc atataggatt
    14461 catcatcaca aatggcaatt gaaatcaata tatacacctt ctttcttatc attattctaa
    14521 ttattatata aagttaattt tttctgttca attaatatga tctaatatgt tgaatatttg
    14581 ttccaaaatg taataatctc gcttttcata gtatatctaa tttgaatttg tgtatcaata
    14641 ttataataaa ctaatttatc acttttataa atttaattta aaaaaatgca aatttcgaat
    14701 ttacctaata aaaaaaagat atcgtaaaat aattttaaaa aattattttt tgatatcttt
    14761 ttttatttca gtgttgtgtt gtatttttat tattcaaata ctgtttgttc ttctatatct
    14821 tctgttagtg catttaaagc ttttaaaact atattctttc taattttttt actttcctct
    14881 tctcctaaca taggatttcc aagtggatat ggtatcccta ctgctggaac aattctatta
    14941 gctcctattg taagtgatat tggtactact gtacatatat gaacaactgc tataccagct
    15001 ctctcaatct cttttaccat cgttgctcca caacgagtac aagtacctca tgtagaagtt
    15061 aaaattacag catctacatc atcttctaac aattttttag aaaactcttc tccaaatctc
    15121 ttagaattgc caacactcgt tcctgttcct gtagtagtta taaaataatc tactaattct
    15181 ccaattacac cttctttttc aagctctcta actacatcta gtggtacaac taaatttgga
    15241 ttttcaagga catatgctct gtcatacccc ccatgtatag ttgtaaattc tttatttgac
    15301 atagaatcca tatctgttaa atcgtaaatt ccatatttag tagcacttga agattcaatt
    15361 ttgtctggat tatcaattgg aactatccct ccagaagtta ctagggcaag ttttatctta
    15421 gataaatctt taacaggttt cataggtgta actctatcaa attcaggcat tggatactca
    15481 gtttcaaagc tttccccttt catcttttta accaacatat caattgctct ttcagaccct
    15541 ctaagttcat ggaagaaatt ttttcttatt cctctcatta tatatccttc ctcttcagga
    15601 ggtcctattt cctcacctct aaccaattta agacctagtt ttgtcattat tggaactacc
    15661 tttctaagac ttgctgctga atttcctgta gacactatat gcaaatctaa tttaaacata
    15721 tctacacctg gattttcttt atacatgcct gtaattacag gaatatttaa ctcttcttca
    15781 actgccttac aaatagtccc acaagctact ccatatctac ctgcattaaa tgctgggcct
    15841 gcaataaata aatcagggct ttcttctttt atcattttta aaagttcttg agttgcactc
    15901 tcaatatttt caccaaaata cgtatctccg caaattacag ttgagattat ctctgcatca
    15961 tcattaaatt gactctgaaa tgctattcca ggtcctacta caccagccct tttttctggc
    16021 ggaatatctg ctttttcctc tccacctata ccagcaaaga aattgtttat ataatgaacc
    16081 actctgattt tactcatctc ttaatcctcc aaatcacttt atagttatta catcaattag
    16141 accaatgatt acatcaacag aactttatat tcaaatactt atttaataat atcttgctgt
    16201 caaatgatta tagccatttg ctatagttga tgctattata atttgtagct ctgcatccat
    16261 gcttccgtct tcatttaagc atcctttata cccacctatc atcatttcaa cataatctaa
    16321 agttcctata attttttcca ttgctgggaa atgaaccact agatttcctt gaccacaaga
    16381 aacaactgca tctgcttcct tagtagcgtc tgctatagat tgactcttgc catcttttcc
    16441 aggaaattca tccgttatca aaactacatt tgctccaact tcactacatt ttctacaatt
    16501 catcattagg tcagtatctg gattcccata accttcttct gtcactagaa ctccatcaac
    16561 tcctaaaaat tctattaatt tagctaccat atcagagctt ctctctttat cgactaagaa
    16621 tacgttctca ttagtcaaaa taactcctat aaagtttaaa tcttttccat gtcttttata
    16681 taagtcatgt ataactggat tatttaaatg atggaatgtt gtaaccttat cacatggtgc
    16741 tacacagttt ccagatatta tagctccatc cattatttca gttggataca taaatgtagg
    16801 cactatctgt ttagcatcca ccccatagta ataagtgtca tgtaaaagtc cttgtgattg
    16861 taacatgtga acatatgcta ctgttggcag gtctggatat tcttttactt gttttaataa
    16921 tggctttgtc tcatatacaa tgacttcatc tggctcaact tctcttcctg cctcacctac
    16981 atatgcacct atttttaatc ctgcaattct agctgcttct tcataatcat gagtatctat
    17041 accatccttt gcttttataa caatacatat attatttgtt tttgaaaaag gtgtatattt
    17101 agcagtagga ccactcatat caattacgcc ttcttgaaat ccaactatat ttccacaagt
    17161 tacaacacaa gctcctaaaa gtacatgggt tcttccactt cctacagtct tcactttatt
    17221 tataattcca ggaaatattt tgctttcatc tccaatttta actctaggct ctattacatc
    17281 tttaactgga gctattctta ttgattcgcc aggtcttgca agttcaacat ttacacttac
    17341 aatcctttca tcttctaata ctatcttttc tatttcttcg ctactaatat atagtactcc
    17401 atcttttact tctgtctttt ctccaaattc aacatttttt ataaatatat tccctagctc
    17461 tagcttcata tgaaaatccc ccttaatata tttaatcgca attaaaagta tttattacgt
    17521 ttattaatat ataaagcatt ttctatgcca attatttaaa atatatattc tatgtattaa
    17581 tgtcatagaa attttcattt ttaatttaca ccaatattga atttaccaat aattattgta
    17641 aatattaatt tttaaaatta taataaaaaa agataaacag attttttctg tttatctttt
    17701 aatacagttt gagaaatttt tttctcactt aatgagaagt ttttttctca cttaatatta
    17761 tactctgata ttttattggt taactgtctt ctactaatct ccaatttttt agctgtattt
    17821 gaaatattat ttccacacaa agataaaact ttttcaatat actcacattc aaactctttt
    17881 cttatttctc ttaaaggtct aatacttatt ttatcatcta tgtatacatt atttgatatt
    17941 aaatttaaat tgtcttttga taaattgcct tcttcactta aaactacaag tctatttatt
    18001 atatttttta attctcttat atttcctgga taattgtaat ttaataaaaa atcctttact
    18061 tccttatcaa tcgagtgtat ctttttatca tgttcaattt ggtacttatt taagaaaaat
    18121 tctataagag tagttaagtc ttctcttctc tttcttagcg gtggtatagt tattgttatt
    18181 gtacttattc tataaaaaaa atcttctctt atatttccat ttgatatttc cacttttggt
    18241 tctttattca tagcacaaat taacctaaag tcaactttaa tagatttatt acttcctatc
    18301 ctctctatag atttgtcctc aagtgtcctc aaaagtttta cctgaacatt tagaggtata
    18361 tctcctattt catccaaaaa tagagttcct ttattcgaaa gttcaaatct accttttcta
    18421 ctatctactg ctcctgtaaa agaacctttt tcatgaccaa acaactcaga ctccaataga
    18481 ttttctgaaa aagaacaaca atttacaggt acaaatatct cattctttct tggactcatg
    18541 ctatgtatat atctagctaa tatatctttt cctacaccag attcccccaa gattaatata
    18601 ttaacatctt tacaagcagc tttttttgct atttttatga tattattaaa atctctattt
    18661 ttagattcca aagtaaattc cagattattt ttttgtacag aaacagatat tttacttgcc
    18721 tttacctttt caacttcttc taataaattt tcaatgggat tactttttat aaaataagat
    18781 aaagctcctc ttttcatagc atcaactgca ttttcaatac ttccatatcc tgtaactaat
    18841 ataacctcta tatctctatt aatagattta attctatcta atagctgtac tccatccata
    18901 tttttcatca taacatcaga taaaaccaaa tcataatttt tatctttttt aattatattt
    18961 atagcttctt caccacttag tgctatatct acaagatagc ccttcttttg tagaattttt
    19021 ttcattacca ctccatattc tagctcatca tcaactaata gtattttcat tatatagtca
    19081 cctctttatt taatggaatt tttatatgaa aacaagttcc aacccccaat ttactttcaa
    19141 cacttatatc tccattattc tttttaatct cattataagt aatatataaa cctaaaccag
    19201 ttccctcacc aattggtttt gttgtataga agggattaaa tatgtccttt agggcatctt
    19261 cttttattcc ttcaccatta tctttaaaat ctataaataa acaatgattt ttttcataac
    19321 agtatataat aatttttcca tcttgatgta ttgcatctat tgaattagaa attaaattta
    19381 taaatacatg ttttaacgat tctccattta tatagcatat taaattatgt tcacagtcaa
    19441 tttttatttc aacattcttt aactgtaaca ttttatattg aagtttcact atattttcaa
    19501 taaaatttct tatatttata tgttctaaat tatcatctga tattcttgcg aaatttaaca
    19561 agttggttat tatattactt gccctatcta cattactttc tattgattta acacaatcat
    19621 ttacttcttc cattgtaacg ttatctttta agagatagca attatttctt attataccca
    19681 aaggatttct tatctcatgt gctaccccag aagctaattg ccctatagat atcattttgt
    19741 tttctctaag taatttcgcc tctactattt tatcattagt tatatcttta ataagaacta
    19801 ctatatactc agtattattt tttttatact ctacaggaaa agtgtttatc tttaaaattt
    19861 tattgtgtat ttctatttca ctagttttat tagtattttc agagaaggta ttttcaataa
    19921 caccttttat catgctaatc aaatctgcta tcttataact catttcaccc ataaagtcat
    19981 atagtacttt gttcgattct actatattgt tattttcatc tacaagcatt attatatctg
    20041 taatactatt aaaagttgcc tctaaagttt ttttattttc tattacctgt tctgttttcc
    20101 ttttgatttc tatctttaac aaatatgtat agctataaaa aacataaatt gatattaaaa
    20161 ttatacctat aaaaagataa atactaggca caattcctcg ctcatacaat atatcatcaa
    20221 cttcattata cgtagaatac cattttttct ttaaatcttt atacactcca tttttctgaa
    20281 gtttaaaaat gcctttattt aaaatactaa ccagctcttc atattgttta ggtacagcaa
    20341 gaactgcttt tttagtatat ataggattac ttaaaacact gtatttattt gaaagtccat
    20401 aattatttat atagtatcgc aatactggtt catcaccaac aactgcgtct acttttccag
    20461 acattaaatg gttgactcca gtctttatat ctggagtcaa caaaatgttt atatcttgaa
    20521 ttttttgctt taaaaaattt atagaataat caccttctgg aattgctact gttttcccct
    20581 ttaaatccat gtaactattt atatcttggg actttttatc tttcaatata tttgcactca
    20641 aagtgtatat tgggtcagta aatataaatt tatttgccct ttcttttgat ggaatcaagt
    20701 caaaaaactt tatactatca tctattgaat ttacgaaaga ttctttccac caattatttg
    20761 gtttaaaata aaaatctcta ccaatttgaa ttgacagaga atttattaaa tcaacaataa
    20821 ttcccttata ctgtccatct tccttacctt tatatctgaa aggaggtgaa ctttggtcag
    20881 agctgtaaat caaattcttg tgtttttcta accacttttt ttcttcttct gtaaatggaa
    20941 gtgacttctt aatatattca aatacattta gattatactc catatttaca taggtatttg
    21001 taagtgaaaa tactactaaa aatgaataaa taatccctat aataacaatc ttttttttat
    21061 tcactttaaa actccaatct tcttttttac tataataaat tcaatattta ataacaaaat
    21121 cctacttttt tcattaaata tttatattta ttataaaact aattgaatag atgttgaaat
    21181 tatagtcatt actattccta tcaatgcttc atatggaatt aacttaaatc tttcacctat
    21241 atccatgttt atactacctg cactagtatg aaatagtgag ccatgtggta attgctcgaa
    21301 tacactagac ccagcattta ctattgatgc acctgaaatc ggtgatagcc caccatttat
    21361 tatagcatca tgaaaagtag atgatgctat agtagcacca gctgttgatg atgctgttgc
    21421 taatgacata agtatacccg aaactggtgc caataaaaat tgtggcatat ttaaaaattg
    21481 taaagcacct attgtactct gttgtaattc agacatctgt ataattcctg cgatagtccc
    21541 tgttccaagt aataatatgc ataccccttg catcttagat aatccaaaag ctaaatattc
    21601 tcttgaattg ttcaagtttc ctgtgacaat tagagttacg attcctccta ttggaagggc
    21661 tatcataggg tctataacta taggagatac atttcctaaa aacaatagaa atatagctat
    21721 aattggacca cataatgatt taaataaact tggtaaatct tctctttgct ctaaaatttc
    21781 atatgattgt actttatttc ctttatttat taatatactt gctaaaataa ctgtaataac
    21841 aactccaata attgctggaa ttatatttgc aatcataaca ctagagagat tgacagaaaa
    21901 attatctgct actgctatag tatttggatt tggtgatatt atattacctg ctttaccccc
    21961 tcccaacata gctaatagta ttgacaattt agaataattt aatttcctac ctatatataa
    22021 tcctataggt gctacagtta ttatagatac atccaaattt acgcctactc cagcaagtac
    22081 catagttgaa atggcaatcg aaaataaagc cctcttttca ccaaatattt ttacaatctg
    22141 ttctgatatt ttatctactg cccctgtttt tattaaactt ccagctaata cacctgatgc
    22201 caaagctcta agaattgatg gtgatatatt catagctcca tttgccataa aatctacagt
    22261 ttgtgttata tttgctcctc caactaatcc tccaataaat gctcctaaca ttaaactata
    22321 tacagcttga aattttttta taattaaaat aattgctatt aataaaccaa atatagctcc
    22381 aaaagtcgtt atttgcataa tatcccctcc tatcataaat taactatctt ttgcttaatt
    22441 ttatttaaat atattttaag tattctgtat ccactttgtc aattatattt taatttattt
    22501 aattatattg aacatagttt tttcaaaacc taattctata tgttataata atttcatact
    22561 acataatcat tttacttgat tattttaagt taatattttt taaattaaaa agagaggata
    22621 tttatatgaa tgatttaaat ttaggggaaa aaatagctga agttcgaaaa aaacaaaact
    22681 taagtattcg agatttagca aaactagctg atgttacacc atcattattg agccaaatag
    22741 aacgaggtct tgctaatcca tctgtaaatt cattaaaatc tatagcctct tctctaaacg
    22801 ttcctttatt tacatttttt gtatctgaag tagataaaaa aaacttgata gtaagacatg
    22861 ataatagaaa aaaagttatt ttacctggaa gcaaagaagt tatatatgag attttaattc
    22921 cagactctag tggtaattta gaatttgcaa ttatggattt agctccaaac acttcttctt
    22981 gtgttgatag gattactcat aatggagatg aaattgcata tgttttggag ggagaagtta
    23041 aactttttat ggatgatgat gaatttactt tgtccaaagg agatagtgta aaagttcctt
    23101 taggaacaaa gcataaatgg caaaatgact caaatagtga aagtaaagta atttttgcag
    23161 tcatcttgta aaggagtaaa aaccatgaag acatataaat ttatattttt tgatgcagat
    23221 gatactttat ttgattttaa gaaaagtgaa tcacatgctt ttaaaaaact tctatctgag
    23281 tttgatttag aatttaattt tgagaattat atagagtcat atagaaatat aagtgataag
    23341 ctttggctcg accttgaaaa aaatattata actttgaatg aacttaaatt acttagattt
    23401 gaactttttg caaataaaat atctttggat gttgattctg aaactcttag caaaatgtac
    23461 ttaaattttt taggtgaatg tacattttta attccaggtg caatcgatat attacaatat
    23521 cttaaaaaaa agtatactat tgttataata acaaatggaa tttctgcagt tcaaaagaaa
    23581 agacttgaaa attcaaaaat aaaaggatat attgatggaa tggttgtatc tgaagagttg
    23641 aaaatatcaa aaccaaatcc tgaaatattt aaatacgctc tcaaaaagtt taattgtcat
    23701 gataaatctt ctgccttaat gattggggat agcttaacct ctgatgtctt aggtggaata
    23761 aattcaggaa tagatacttg ttggttaaat tccaataaca gtataaatta tactaatcat
    23821 ataccaactt atgaaataaa tacacttatt gaattaaaga aactactata gtttgtaagt
    23881 ctgttcaaat taaatagaat attactttgc aataattttt ttagtttata cataaaatga
    23941 ccaaaaaaat tattgcaatt catacacaaa acaaatctta gtcttgaaaa ttaactaaaa
    24001 gcattttcta ggacacttac tacatcttga ttctaaattt tcttcatccc ccattaaaat
    24061 aagcattgca acacttttta tgggggatag ttgatgataa tcattgattt ctatttctat
    24121 actattatat ttatttttta catagttata aatatccttt tgtctctcta cttcaaaatc
    24181 tttatctcct ggatatattt catgcgatat tttgagacta tcatactttc cttttaaata
    24241 catttttatt ttctcattaa tataatctaa acatactata cctattttat ccaatgctat
    24301 ccctgccatc atattgcaat tttccatata gtcattcatc ttaaaatcaa ttttatcccc
    24361 tattgtatat agtacagcaa atgctttttt acattcttta ggtgttttat taatatcaac
    24421 ttcacttata tatatcttga tatctaaaat atcatttata tttcttattt ctctttcaac
    24481 gattttacta attgtatctg gagcttttct atttccatac cccaaaaact ttagcacaat
    24541 attcttatct ataaaaatat catctaaatt tatatccttt aaaagatatt tatttttatt
    24601 actattataa ttcatcaata tcaatcctat ctaattcttt ataactaatt cttcctgcct
    24661 ttatagctgc ttgtaaattt tctactggag tggtatttaa gcagttacag ccaaaatcac
    24721 ataaaaagtt atcatatcct ctcatcttct ttaacaattt tagtgtctct cttctaatct
    24781 tatctggctt agaacgtcca agaagtttta ttgggtctaa attaccaatc aaaactatat
    24841 ctctaggaat cattggagca atttcttcat agtctaaaat ttggtctaaa cttactgcat
    24901 ctatattaca acttagcata ttatctaata attctctggt gtctccacat atatgcatac
    24961 ctttccaaca atcaagttca ttgtagattt tatttaaatt ttttactata aattcatcaa
    25021 atctatcttt acttagggtt actgatgttg gctctgctat tgaaatatat tttgctcctg
    25081 ctttatttgc agctacagca tatcttctta ccaattcagt tgtaaattcc aataattctt
    25141 ctacaaattt tttatcagtt attatacatc ttaaaagttg agtagctcca gctaattgac
    25201 ctgcaagtgt aaatggacct tgtatcgatt catatagtgg ttttttaata ctttttgata
    25261 taactgataa gctctctata ttgagtggca tacgtccact cgtataaggg tctggaacat
    25321 ctaattttct taatttatct ctgtcagtta tagtatgtgt caatacactt ggaaaatcat
    25381 aatctggtct taatgtatct aaacccagag tttcacaaaa tgtaatccca tcacagaatg
    25441 agtatataaa atctgattca aaatacttgt ccatagtctt tgctaattct aattgcaaat
    25501 ctacactatc atatacttca tatgcctttt tatttattaa gaacaatcca tttgtaccca
    25561 tatcaggcag aaaaaaacct ctatcttcac tatttatata ctgaagtaaa gtcatatctg
    25621 aaaacattta aacttcacct cctataagtt tatttattaa tttaactgct tttggagcat
    25681 ttgaactgta tccatctgct cctatttctt ctgcaaactc catacttaca ggtcctccac
    25741 caattattac ttttggtctt ttatctatct caatcatatt aagttcgtct ataaccgatt
    25801 tcatattttc cattgtagtt gtcatcattg aagataagcc tattatatct acattgtttt
    25861 ttatagcttc ttctattata tcttcacttt ttctatttac acctaagtca ataaccttat
    25921 atccagtggc ttctaccatt acttttacaa tattttttcc tatctcatga gtatctcctt
    25981 ctactacaga catcagaatt actccctttg attttttctt tacttttcca gttcccttca
    26041 aaagattaat acctttattt aatgcatctg tgcatactat aacttctgaa agatagtatt
    26101 ccttattctc aaacttatct aaagctccta tcataccttt gtttaaacca tattcataaa
    26161 tatcttccac atcaatattt ttatctatag caatttttac taaattctct atattatcta
    26221 cacccatatt taatatacat tctgctatat catcaagtat gtccatataa tactcatcct
    26281 ttctaattac ttacaaaatt gctttttcaa tatccaataa tttctcttat ttaacaagga
    26341 ctaactctag gtatcaatca attttattta atatcatcta aaactattga taatttaaat
    26401 ttgcagtcca tggaaaatct acaggaaatg cctttgtagc aaattcatat atatttttta
    26461 gatgtttaaa ttcattgtac tgttcctcat ttttttcaaa aaacagttta ttaagcttat
    26521 ccaaattttc tattacaagt tcttcttctt tgtatttaat aatatattta ttttcaactt
    26581 gtttaaattc catgtatttt agtaattcaa aatctgcata ttgactaaaa taacttctta
    26641 aactatcaca caacttagta aaatttatta ttttcatagt tccttgttga taatccaaag
    26701 attttgtccc attacatttc aactggtctt taagattttt cacatgtact ttataattta
    26761 aagattctaa tccaaattta tttgcaacat atttcaatat attttcaaca tttacagagt
    26821 ttaaccctat ttcagcaact tctcctacag tagaatcttc tttttttatt gttcttatta
    26881 tcaaatatcc tattatatta ttattttcct ttataaatac cttcttgtaa ccaattggtc
    26941 cccaggcaat agttgctgca tgcaatagtt tttgaaactc atctctcgtt cttataaatc
    27001 tagtactatt ttgattatat agttcaatca ttttatctaa atcattatct ttttcaaaat
    27061 tagtttcatc aaattcaact atttcatatg ctatttttac atcttcaggt tttattgtat
    27121 atttataaaa actctttacc aaactacaat ttcttctact gtatagactt cttgttcctg
    27181 atataattac aatatctaca ccatcataaa acattttttc ttctacttta tccaatatct
    27241 tagatgaata gcctctcttt tcataatctg gatgagtaca tactccacct atagctgcaa
    27301 ccttcaatct gtttccttga atagatacat cctgaattag atagtttaca tcagaaacca
    27361 ctttatcatc ttctgatatt ataatcatat tttctatatt atttttactt agtaaaagag
    27421 gaaattcttc catcatagtt ggtttatgat ttcttgatat tctaaataca tagtttatta
    27481 attctattac tttatcaaat tcttctaatt ttgcacttct tggtcttaat tccattcata
    27541 ttcctccaaa tattatttaa gatacttaaa actctattat ctataataaa acatttatta
    27601 ctacagttct aattatatct tttttcttta caatttttaa ttgttttttt tagcaaattt
    27661 ttataaaata taaacctaat ttatagttaa atttataaaa taacccgtta tgtataatat
    27721 attaaaatat tttctatata tttatatgac taagttctat aactaaattg aaataatcac
    27781 tttttcaaga atgttataat ttttttattg tattcttttt gctatagtct atgaataaat
    27841 caatagaaaa tcttctaagt tgcttttaaa taatgacttt atggttcaat tgtactaaaa
    27901 tagtatatgt aggttacaaa taatctaata aatattaaag tttggaggta atagatatgg
    27961 cagattgtaa ttcatgtcca tcaaagggaa attgtaatag tcaatcaaat tgttctattg
    28021 aaaataaccc taacaataaa tttggaaaaa taattggtgt tatgagtggg aagggtggag
    28081 ttggaaaatc aactgtaact gctttacttg ctaataagct aaacaaaatg ggatataagg
    28141 ttggtatatt agactcagat ataactggac caagtattcc tagacttatg ggtgtaaaaa
    28201 atgtaaaagc ttattctgat ggctcttata tttaccctgt agaaaactca aataacataa
    28261 aagtaatgtc tataaacctt atgatagatg atgaaaatga acctgttgtt tggagaggac
    28321 ctttacttgg aggggttgta aagcaatttt atactgatgt actttgggaa gaattagact
    28381 atttattaat agatatgcct cctggtactg gagatgttgc cttaacagtt atgcaatcta
    28441 tccctataag tggaatagtt atggtttcag tacctcaaga tttggtatct atgattgtat
    28501 caaaagctgt taatatggct aaaaaaatga acataaatgt ccttggagtt attgaaaata
    28561 tgagttatat ccaatgtcct gattgttcta aaaaaatcaa gttatttgaa ggagaatcta
    28621 ctgaaaagtt tttagatgat ttagacttag agcttttagg agaacttcct atgactaaag
    28681 aaattataga tattactcat aatggagtta cagaaattag tgatgattta gattcaatat
    28741 tgactaatgt tgttgaaaaa attaaataaa taaaaatttt ataattttat atttatcaaa
    28801 aaaagaggct tgtatttatt ttataatcat acaaataaat ataaacctct tttatgttta
    28861 tctatgtttt aaatacacaa aatattcttc tacttcatct ccatttttta cttttactaa
    28921 atattcatta taatgagcat tatatggctg tgtcattttg cattctatta cattttctat
    28981 gtcttctaat tctaaaagtt ctacatcctt taaaaatttt ctttctatga gttccattaa
    29041 tctttccata atatatcctc acttccccta taattaagat aaactatata tcctcttaat
    29101 gcagagttta tctgtttatt atattatatc caatatatta cagtttctaa catcattcat
    29161 aaattatttt aacaaataga gattgatttt ttaataaata tgccttgata aaatgaaaca
    29221 tagaccaact cttagtttta tgtaaagaaa acttaaagaa aactataaat tatattcaca
    29281 aaaattactc agaagatata acagtaagta atatatgtaa tgaattacaa cttaataaaa
    29341 gttatttttt ctttgtttaa gaaaaaaagt ggatatactt ttactaattt tttaaataaa
    29401 gttagagttg aaaaaagcaa aaagtatata ttaaaaaaaa acttgtctat tttagacgtt
    29461 gctgtactaa ttggattcaa tagtcaaaat tactatagta taatttttaa aaagtttaat
    29521 aactttacac caattgaata taaaaatatt tataactaaa aaatatcatt ctaaaaggat
    29581 gttatttttt tacatatttt ttacaattat agttaattct ttgttaaatt gattgtacat
    29641 aaaatactaa aaatctaagt tcaagtattt aaattgctat atatcataaa ttttctaaaa
    29701 ttaacaacaa cttaaaaatt taacattctc ttaacgtata cttaacaaaa cattaatatt
    29761 tttattgaca aaatttgtta ttctatatta tggaaacaat aaattttagt taataaagtt
    29821 tataattcag ataaaaaaat tattaatttc ttaagggagg aaatatcgtg aatatagtaa
    29881 ttagccttat cggtggactt ggactttttc tttacggaat gagtttaatg ggagaaggtt
    29941 tacaaaaatc agcaggagac aaattaaaaa aaattattga actcttaaca agtaatgttg
    30001 ttatgggtgt actggtgggt acagtcgtta caggtattat acaaagttca agtgctacta
    30061 ctgttatggt tgtaggattt gtaaatgcag gtataatgaa tctaagtcaa gctattggtg
    30121 taataatggg ggcaaatata ggtactacag ttactgctca attagtttca tttaatcttg
    30181 aaggaattgc accaattgct ttaggtatag gtattttatt ctatttattt acatcaaatc
    30241 aaaaaacaaa gcatttgtct gagatactta taggtttcgg tatattattt acaggaatgg
    30301 agtttatgaa agatgcagta gctccacttg ctgaatacaa agcattcact gatgcacttt
    30361 tatattttag taaaaatcct gtattaggta tattggcagg atttgccata actggtattg
    30421 ttcaaagttc aagtgcatct atgggtatgt taatagcact agcttctcaa ggaatacttc
    30481 ctctatcatc tgctttacct attctttatg gagataatat aggtacttgt gttacttcac
    30541 ttttatcaag tgttggtgca agtagaaatg ctcgacgtgc agctgtaatg catttaagtt
    30601 ttaatgtaat tggtacaata atatttatgc ttgttttaaa taaacctata tcagccatag
    30661 ttactcattt tgacccaact gatacagcta gacaaatagc aaatgcacat actttattta
    30721 atcttacaaa tgttataata ttattaccat tttctaaata catagttaaa ttagcaaata
    30781 gacttatacc tattaaagaa actgaatcag aaatagtaaa taatactaag tacttagatg
    30841 aaaggatgtt tagcactcca tctatagcac ttggtaatac tgtacaagaa gttgtaagaa
    30901 tgggtcataa agctacaaac tctttggaac attcaattgc aggattttta aataagagca
    30961 atgaagatat taataaagct tttgagtcag aaaaagttgt caataagtta cagaaagata
    31021 tattgaacta tttgttaaaa ctttctaaag aacctcttag agatgatgaa cgctttagaa
    31081 cagatttgct ttttaatact gtaaatgaca ttgaaagagt ctctgaccat gcagaaaata
    31141 tagctgaatt ggccatgagt gttaaggaaa tgaacattag tttttctgat agtgcgataa
    31201 gagaaatata cgaaatatac aataagacaa ttactaattt taaggatgcc ttaatagttt
    31261 tagatgttaa agattttgag ttagcaaata aagttttaga agttgaaaat gaagtaaatt
    31321 atttagaaaa aacttttaga aattcacata tgattagact aaataatgga agttgtacaa
    31381 ttgatgctgg tgtactttat cttgacttac ttactaatct agaaagaatt tctgaccact
    31441 caacaaatat agtaaaacaa gtactaaaac ttaaacaaaa aatatagtga ttatttttat
    31501 atataatctt aatcaatgag aagtaagaag ctatagataa tgcttatatc atttatggct
    31561 tcttattttt tatgtaatac tcaaattttt atagtattct cttattatta aacaatttct
    31621 gcctagaata ttccatatat atatgacttc tttcataaaa cttgaactgc ccataactaa
    31681 agtcacaagt atacataact attttttaat caattataac caatatttgt tttatttatc
    31741 ttcattttaa ttcttcattc aataatgtaa taagattatt ttttatttgg atactattat
    31801 atcatctaaa tatgttatta tatatttgga tattttcata ttaataggag ggattctaca
    31861 atgataaatt atatggtaga aattatatat agcgaaaaaa taagcgaagt agaaaacatg
    31921 ttgaaaattg aaaatataca atatgaattt acttctcgtg atggctttat attttttggt
    31981 ttttatgata tgacagacgc atatagattt gagactttat gttcagatga aaaaattcga
    32041 tttaaaagaa tataatagat aaaaaagtac atatttctaa actatttgtt tttcaaattt
    32101 aggttgtgtt ttaatgtagt gttgatatta taaacaattt taataataaa aaagtaggga
    32161 cattatatta atatgctcct actttttact catacttatt aatattattt atcaaaatta
    32221 ccctacaaac tggaatttat cattctttca taattttaaa ctatcatatt taaaatatat
    32281 aaaattctac atgatttttg tataaacata atatcaacca ttatccaatt taaaaatatt
    32341 ttttagtaat ttccatttca ttttctctta acatattaat taaactttta tatgtaaatg
    32401 gtgtatttac atattattta atatccaaca attatataaa gaaatgtgct ctttgcctta
    32461 taaagaatta taaagccaat tcgttttatt atattatttt tctttatacc ttaaaaactt
    32521 taccttcaaa ttcttattta tctatatatt ataaaaatgt tcttaacctc ttttacgaga
    32581 ttttcttgac atattatcag ttagataaaa taattaaata atataatcag taagtatgtt
    32641 ttttactctt ttaagtaaat ttccacctgc accccaatca atttttaaaa ttccaattgc
    32701 actgcctgtt gaagtagctt taataactgt ttttcctgtg gtattttcat aaactactat
    32761 taatcctgca tcactattat ttcttgcata atacttctca aaagttgtaa ttagtataaa
    32821 tttatcatct cctaaattat aagaatcact aaaaactaaa tctgcatcaa gattttcttt
    32881 tatcattttt tgtgcctcta agggtgtaat ttttacagta aatatttctg ttgccatttt
    32941 ttatctcctc ataagaattt attttagaca aaacataatc tctagtattt tctgatatat
    33001 ttatcaaaca atatccctat tcctcctaac agagctaata tagaaccaaa atttctatat
    33061 tgagaaatag attggtctag ataaatatta tattggtcag tatccatgat tccaccattt
    33121 tgttgaataa tatgctctgc actaaattca cctaaaccta tacaacagaa taatactact
    33181 actccaatta caaaagcaaa tatacatatt gttaatttaa aatccttatt ttccatagtt
    33241 atccctctca taagctaaat ttatttgatt atttttacta gattttatat tactcttatt
    33301 atacaataca acatatattt acatctattt ccaaaattgt aacctttata gttttatata
    33361 tttaaatttt ttaaacaaaa aacacaataa aaatctgatt atccgctaaa acacagtatc
    33421 tatcagcatt ttcaaggaaa caaacacatc aatttactac ttatttacta ctaacgaatg
    33481 agccttgata cgcaagtttt cctagatatg caaagatatg gtacaacaca tcagtattga
    33541 aacaagaaaa aattgaataa cttatagact atggaacgcc taacatgacg ttccttttct
    33601 atttccagcc gttcttattg gacggctatt ttattaccca aaatgaaagg agcattagat
    33661 ttatgaaaaa gatgttaaaa cgattgtgta ctggcttctt agctcttgca actgtcgtta
    33721 ctactttacc gacgacaccc gttcatgcag aaagcaagca atactggacg gagtcaaaag
    33781 agcgtgtcgg tatcgttgaa aaagtaatga atgacggttc gattggttct acttttaacg
    33841 agggacattt gaccgtcgag ggcgaggacg cttactgtat cgacattaac acagatttta
    33901 ggaatggcta caagaccaga attgacgcaa gcacccgtat gagtgccgac cagataagcg
    33961 acgttgcctt atctatcgaa tatgtgaaac agtacacaga cagccacagc ggaataagca
    34021 acaatcacgc ctacctttta agacagcttg ttgtctggca gagattgagc gtacatcttg
    34081 gctggcaatg cgacaacgtg agagcttctt atgatgaaat tccaaaggca acgcaggacg
    34141 aagttttctc tggtgcaaga gcctttgtca aagaaaataa aggacgttat gaatgtggcg
    34201 gttatatcta ctctggcgag gggcaggaat tggggcaatt ctgggcgaag ttaaatatcg
    34261 gaaatgcgaa acttaaaaag gctaccagta ataccagcat tacagacggt aacgggaatt
    34321 actctatcgc tggtgcaaca tacggtgtct tttctgataa gaactgcacg aaacagcttg
    34381 ccactcttac gactgatgaa aacggaaata cagatgttgt agaggtaaaa gcaggcacag
    34441 tctatatcaa ggaattatcc gcaccagcag gatataaagt agataaaact atatattcct
    34501 taaaggttga agctggaaaa acagcgactt tgaaagtatc tgatacacca aaagtaacgg
    34561 acacgttgat tgagcttttc aagattgata tggaaacaca gaaagacaat ccgcagggga
    34621 acgcttctct agcaggtgcg gaatttacat ggaagtatta tgcaggcttc tataataaag
    34681 acaatctccc tgccgaagct actcgtacat gggttacaaa gacaatcgct gaaacagaca
    34741 gcgacgggtc aacccactac atcacaaaat ttgcggacgc atacaaagta tctggcgata
    34801 gcttctatat gcaggacggt aaagcggttc ttccacttgg aacgctaacc gttgaagaaa
    34861 caaaagctcc aaacggatac ttgttagacg gtgcatatat gcaggctggc gataagtccg
    34921 aacagataaa agacttatac cttacacaga ttaccgagga cggcgacctt gccgtattat
    34981 ctggaagtaa ccagttttcc gtatcagata aggttatccg tggcggtgtg aaaattcaga
    35041 aacgagattt agaaacgggc gataccaaac cacaaggaag tgcaacttta aaagatactg
    35101 cctttgacat catttcctta aatgataatg cagtattggt tgagggcaag ctctataaga
    35161 aaaatgaagt ggtaaagaca attcgtaccg atattgaggg tatcgcttct acttctgctg
    35221 accttttacc ttatggaaac ttccgtatcg ttgagagcga agcaccagac ggatatttga
    35281 cagacggtgc aaaaccgatt gattttacaa tcacagaaaa tggaaaaatc gtggacttaa
    35341 ccgacgaagc ccattctatc tataatcaga ttaagcgtgg agatattgag ggtgtaaaaa
    35401 tcggtgcagg cacacacaag cgtcttgctg atgttccttt taggatcaca agcaagacaa
    35461 cgggcgaaaa tcatatagtt gtaactgatg ataacgggca gttttccact tcttctgaat
    35521 gggcttcgca taagcacaat accaacgcag gcaagaccag cgaggacggt gtgtggtttg
    35581 gaacttctga accagacgac agcaagggtg cattacctta tgatacctac atcattgaag
    35641 aaatgcgttg cgacagtaac aaaggctttg aacttatccc accttttgaa atcgtggtat
    35701 caagaaataa ccttgtgatt gatttaggaa cgttgactga tgaatacgaa aaagaaatct
    35761 ctatccatac cacagcgacc agcaaggacg gcgaaaaaac tatccttgca ggaaaagagg
    35821 taacaatcgt tgatactgtc aaattaaacg ggcttacaaa aggcacaaag tatcagttga
    35881 aaggttggca gatgttaaag gaagaaaacg ccgagcttat cattgacggg aaacgtgtag
    35941 aaaacgatta tacctttgtc gctgatgatg aagaaatgaa agtggaaatt tcctatatat
    36001 tcaatgcgtc tgctttaggt ggcaagaacc ttgttacctt tgaagaattg tatgatttca
    36061 gcaatccaga cgaacccgtg aaagttgcgg agcataaaga cattgaggac gacgggcaga
    36121 ccgtacttat cacagagcgt atcatcaaaa ttcatacgac tgctaccgat aaggacggca
    36181 acaaagagct tgaagctgga aaagaggtaa caatcattga taccgtaacc ttagagggct
    36241 tagaagtcgg tacacagtac aaactggtgg gctggcagat gttgaaaaaa gaaaatgccg
    36301 agcttcttat caatgggaaa cgtgtggaaa gtgattacac ttttactgct gacagcgaaa
    36361 ctatgaaagt ggaagttgcc tttacccttg acgctacttc ccttgacggc aaacagcttg
    36421 taacttttga agaattgtac gatttaagca atccagacga tccgaagaaa gttaccgagc
    36481 ataaggatat tgaggataag ggacagacga ttacctttaa ggaaaagcca aaagaaccag
    36541 agaaacccga aacaccaccg acaccagaaa agccaaacag accgagcgac agtcccaaaa
    36601 cgggcgataa cacaaacctt tacggactgc ttgcacttct tttgacctct ggtgctggac
    36661 tggcaggtat cttcttctac aaacgccgta aaatgaaaaa atcataaggc ggtaacggta
    36721 tgagaaaaga aaaatcacgc tctccgccga agttgtcaaa cggcagactt ccgcttattc
    36781 tggcttgtct gccaacaacc tgcaagaaca cggatagtca agggtgcgta agcattgatt
    36841 ttacccttta ctatctgtgg gattgctggt acttcccaaa ccgccagaat aagaaatcac
    36901 aatcaattta tcaaaaatag aaagaaacga ggtaaaacaa tatggaaatg aaatatgtcg
    36961 tgccagatat ggtacagtct tttggaactc ttgaatttgc aggcgaaagt gagccagtct
    37021 ttgaaagaga taaaaataac cgcagggtct tagcaagacg aagctataac ctttattctg
    37081 acgtacagaa aggcgaaaat gttgtggtag aaattcccgt gcaggctggc gaaaaaaagt
    37141 tcaagtatga acagaaagta aaacttgtca atccgaagtt atacggcaga ggttatgcaa
    37201 tcggggatat gggacatacc gattatgtgt tagttgctga tgatattgta gcagttgaag
    37261 aaaagtaaag gagtgaagaa tttatgagat tatcaaacgg gtttgttatt gacaaagaga
    37321 aaacatttgg agaattaaaa tttacagcgg tgcgtgatgt gttcttacag aatgaggacg
    37381 ggacaccgag tacccagctt aaaaagcgta tctatgattt gaagtgcagt ttgcatggtg
    37441 gaattatccc cgtgtctgta ccgccagaag taccgttaag agaatttccg tacaatgcag
    37501 ttgtggagct tgtcaatcca gtagccgata cggtatcaag aaagacctat acgggtgcag
    37561 atgtggactg gtatgtaaag gcagaggata ttgtattgaa gaataaaggc aatcaaaacg
    37621 taggcagtcc acagaaccat acaccgcagg gacagccgaa aaaataggct tgctgaatag
    37681 attttcgttg tagcggatat ataaaactgt tataatatgg gtatgaaaaa tttaattata
    37741 aggagtgctg tttatgataa gagctattat atttgctgta ttcgttgtcc ctattatatc
    37801 tctcgtatta gataagacac aaaaagcaac taaaaaagaa aaattcacaa atactgtttt
    37861 tgtatcacac gcctatcaaa cagtatgtca tatttgttca ttgataatgg taggaattgc
    37921 aatagcttta ggattgttca tgggatttga taatacggtg ggacactctg ttgtttttgc
    37981 tatttttgtt ctattgattg aattttgtgc gtgggcatta aaaagacata aggtagtaat
    38041 tgacggaaat aatttgcgta ttactcctgc tgttggaaga acaagagaaa tttcatttaa
    38101 tgatatttcc cgttgcacag aaaaagagca aataggattg aaaatatttg taggaaacaa
    38161 aaaaatttgt acagtttctt gcgactgtgt tggatataaa gaatttcttg aaatgttaaa
    38221 agagaaaaat ttactctaat acgtttcgcc caaataaaca gttatattat tttagcagtt
    38281 agtcttagga ttgactgctt ttttcatacc cagaaaggag tgattgattt atgcaaaaga
    38341 tttttaacaa aggacaccgt atcagagcca gcgacaagca ccttgtctac cacttttcca
    38401 taggaacgct tctgtttgta ttcgtggcgg ttctcctgct actgaatatc aaacagctca
    38461 tgcgtactga ttgggaacat ttcagcttgt tagagaacgg cttgacgctt tccccttaca
    38521 acttcataac tatactgata gcgactggtg tttgtgcatt ggtcgttttt ctgtattacc
    38581 acttctgtta cgatagtttc aagaagctcc tgcaccgtca aaagctggca agaatggtac
    38641 tggaaaataa gtggtatgaa gccgataccg tacaagacag cggttttttt actgacctgc
    38701 aaagcagatc aagggaaaaa atcgtctggt ttccaaagat ttattatcaa atggaaaagg
    38761 gactgcttca tatccgctgt gaaattacgc tgggaaaata tcaagaccag cttttacggt
    38821 tagaggataa attggaaagt ggcttatatt gtgagctgac cgacaagacc ctgcatgacg
    38881 gctatattga atataccctg ctttatgata tgatagcgaa ccgcattacc attgatgaag
    38941 tacgggcaga aaacggctgt ctgaaactga tgaaaaatct tgtctgggaa tatgacgcac
    39001 tccctcacgc tctgattgct ggtggaacgg gtggcggtaa aacttatttt ctgctgacgc
    39061 ttattgaagc cttactgcat accaacgctg tcctttacat cttagacccg aagaacgctg
    39121 accttgcaga cttagggaca gttatgggaa atgtgtatca caccaaagaa gaaatgattg
    39181 attgtgtcaa tgccttttat gagggaatgg tacagcgaag tgaggaaatg aagcaacacc
    39241 cgaactataa gacgggcgaa aactacgcct atctgggact gccaccctgc tttcttatct
    39301 ttgatgaata tgtggcattt tttgaaatgc tggggacaaa ggaaagcgtg ggcttgctta
    39361 gccagttaaa gaaaatcgtt atgttaggac gacaagcagg ttatttcctt atcgttgcct
    39421 gccagcgtcc agacgcaaag tatttctctg acggtatcag agataacttc aatttccgtg
    39481 tgggacttgg gcgtatcagc gaattaggtt acggtatgct gttcggttca gatgtgaaaa
    39541 agcagttttt ccagaagcgt atcaaggggc gtggctattg tgatatggga acaagcgtga
    39601 taagcgaatt ttacacgcct ttagtcccca aaggacatga ttttttacaa acaatcggca
    39661 ggcttgcaca agaaagacaa gtcatgccag aacaacaagg aaaggaagat gtgattgaat
    39721 aaggacacat taaatgttta tcacgcaccc acagagaaaa actacctctg tttgtgcttg
    39781 aatacagata tttttacaac ggattgcagg aaatatatgt tagattgttt tttagattat
    39841 tctgtcaatc caaatctgcg atttcattca aggatagata aaatcattga tgatgttatt
    39901 cgtgaaaaaa tcaacattcc tcataagttt agaatgaggt tggaaagtag acattgcgtt
    39961 gaaagcagga taatctattt tcgatttcga gttttagata aggcttgtct gcaatgtaat
    40021 gtatttctta aagggctgtc tgaagaaatg aaagaagcac tttcagatga aagaatagat
    40081 tttgcggtta tctatgaggg catacaaggt tcacagcagg acacagacac ggacgacaag
    40141 gacgggtttt gcggttctca accgcaagtt ccgttcttgg cggacggggc ttgtcccgtc
    40201 cgctgataaa acccctcggt atctaacaga ggggtacgtt tgcaaataga caatagacaa
    40261 aaaacatagg aaacataagg cttctggcat ggtttcctag caaaaatcgg ctgtgaagtc
    40321 gcctaaaaaa acttcacact ttacagattg ggggtatggt tctgaatgaa gaacaatgga
    40381 taaaagaatt acgggagaaa cggattgctt acggtatctc acaaggcagg ctggcggtgg
    40441 cttctggtat cacaagagaa tatctcaata agatagaaag cggaaaaatg aagccgtcaa
    40501 aggagctttt ggaaactctg cataaagaac tggcaaggtt caatccagaa gcaccgctta
    40561 ccatgctgtt tgattatgtg aaaattcgtt ttcccacgct ggatatacag catatcatca
    40621 aagacatatt aaaactgaat atcaactata tgctccatga agattatgga cattacagtt
    40681 atacggagca ttactcttta ggggacatct ttatctatac gtcggctgac gaagaaaaag
    40741 gtgtcctttt agagttaaag gggcgtggtt gcaggcagtt tgaaagttac ctgctggcac
    40801 agcaaagaag ctggtatgac tttctcatgg acgcactcgt agacggtggc gtgatgaagc
    40861 gtatcgacct tgctatcaac gaccatacgg gcattttgga tattccagag cttgcggaaa
    40921 aatgcagaaa acgggaatat atcggaaagt ccagaagtta taagttttac cagtcgggcg
    40981 agcttatcaa gcatagagag gacgacagag aatatatggg acgcaccctt tatcttggtt
    41041 cgctgaaatc agatgtgtat ttttgtatct atgaaaagga ctatgagcag tacgtcaagt
    41101 tagggacacc gcttgaagaa gccgacatta tcaaccgttt tgagatacgg cttagaaatg
    41161 aacgtgccta ttatgcagta cgagatttgc tgacctatta tgacgcagag cagaccgcct
    41221 tttctatcat caaccagtat gtacggtttg ttgatgaaga acccgacaag cgaaaaaatg
    41281 aatggaaact caatgaccgc tgggcttggt ttattggcga taacagacag agcttgaagc
    41341 tgacgacaaa gccagagcct tacaccttag accgcacatt gcgttgggta caaaggcagg
    41401 tagcaccaac cttgaaaatg ctgaaaaaga ttgataaagg aaacggtaca gactacatgg
    41461 aaacaatcga acagcaggca aagctcacag aaaagcataa aatgataatc aaacagcaga
    41521 cgacccctgc aaaagatttg gtggaaagtt aggagtgata aaaaatgtgg gtattattaa
    41581 aagatttcct gctggtatct atgggaatgg gtatcggcgt agtcttgatg tgtattttga
    41641 atgtcggcaa agaagctgac tatgaaatga aacaattaga agaaagtgag gacaattaaa
    41701 tgaatttcgg acaaaatttg tatcaatggt ttttatcaaa cgcacagagc ttagtgctta
    41761 tggcgattgt ggttatcggt atctacttag ggttcaagcg tgagttttca aaacttatcg
    41821 gcttcttggt agttgccttg attgctgtcg gtttggtatt caacgctggc ggtgtgaaag
    41881 atgtattgtt agagctgttc aataagatta tcggtgcata aaattttatt gtggtgctga
    41941 tatgcgaatg ttataatgtg gatatgaaac acagtatcta ggagtgatgg aatgaaatat
    42001 ataatgcttc acggtttggg acaatcttct gaaagttgga gtgataccgt aaaagtattc
    42061 aatgatgatt ttgaagtttt atgccctaat ttatcagatt ggctttttgg aaaaatacca
    42121 tgttatgata cattgtatcg gacattggaa acatactgtg aacagtttga agaaccgcta
    42181 aatatttgtg gactttcttt aggtggtatt cttgctatgc agtatgcgat agaacaccca
    42241 gaaaaaatga actcattagt gttaataggc acacaatatg aaatgccaaa gtatctgtta
    42301 aaaatgcaaa atctgatatt ccgtattatg ccttgttcag catttgaaaa aatgggtttt
    42361 cagaaaacag attttatcaa tctatgcaaa tctatgacag aacttaattt taaacatgaa
    42421 ctgaaaaaaa tatcatgttc ggtacttgtt gtctgtggcg ataaggataa gataaataaa
    42481 aaagcttctt tagaattgca acaacagata gaaaacgcag aaatagctat tattgaaaat
    42541 gcaggacatg aagtaaatac agataaccca acactactag ggcaaaagtt aaatgtattt
    42601 ttcaaacaat atgtctgata aacaatttca tatccataca cacaaagcag ttagtcttag
    42661 gattgactgc ttttttcata cctaaatttc agattggagt gatgaaatga acgatatttt
    42721 taaggatatg caggcaaaag tcggctgtga atacatttcc gacctgccct cttacaagcg
    42781 taaggtgtgg catgaaatga aacggctgaa ccctgccgac tatgaagaaa gacagttaga
    42841 agatttttct aaatatgtgt ttggtatctc ataccagaac ttaaaagatg tgatgaacca
    42901 acagaaagga cgtgaggaac aatgcaggaa acaagggtac tggtggaaac gagaggaaca
    42961 actgacgaag aaacaatatc atactggttc gacctgccga tagatgttgc cgagtttgaa
    43021 gaaaagttag gtatcggtgc agaaagtggg gattactgta ttatcgaaaa ggtgttgcct
    43081 tatgctgatg aagttcacga acatacaagc gtgtatcagc tcaacgaatt agattttatg
    43141 taccgccagc tttcaagtga tatgcaggaa gaatatgtat cacttctgac cgtatatgac
    43201 aatttagaag cactttatat ttgcaggaac gtgattacgg tttatcctga ctgcaaaagc
    43261 atgatagatg ttgcaaggca aaagctgatg aacgacccga catttaagca tttatccgag
    43321 gactgtcaag aatattactt tgactttgaa gcctatgctt ctcacttgca ggaacacggg
    43381 aaatttttag taacagaaca cggtatcttt gaactgccag agtaggaaat gaggtggtgg
    43441 ttatgattga tgatatggcg gtttacattg ctaatcttgg caaatacaat gagggatatt
    43501 tagtcggtgc ttggttcacg tttcccattg atgaggaaga tgtaaaagaa aaaatcggct
    43561 tgaatgaaca gtatgaggaa tacgcaatcc atgataccga caacttcccc attgcgattg
    43621 gcgagtatgt ttccattgaa gaactcaatg agatgtatga aatgatagag gaacttcccg
    43681 actatatcgt agagtgtctg gacgaattta tcagccacta cgggacgctg gaagaagtcg
    43741 tggaacacaa ggacgatatt tattattatc ccgactgtga aaccatgaca gacgttgcct
    43801 actactacat agacgaattg caggcacttg gcgacattcc acccagctta cagaactaca
    43861 ttgactatga agcctacggg cgagatttgg atatgggcgg ttgctttatt gaaacaagcc
    43921 gaggtatgtg cgagatacca tattaacgct ggaagatcag cgacaagcat tgttgctact
    43981 gacagcgtat ttctctttta agggacagtc tgaaaatggc tgtccttttc tattttgaaa
    44041 ggagctgaaa gaacttgaaa aagattaaaa gctacacggg tatctggaac gtggaaaaag
    44101 tcttatatgc aatcaatgac tttaacttac cctttcccgt tacttttaca cagattacat
    44161 ggtttgtgat tacggaattt atcatcattc tgtttgggga tattccccca ctttccatga
    44221 ttgagggagc atttctcaaa tactttggta ttcccgttgc tctcacttgg ttcatgtcgc
    44281 agaaaacctt tgacggaaag aagccgtaca gctttttgaa atcacagata acctatgccc
    44341 tgcgaccaaa aatcacttat gcaggaaaag ccgtaaaact gcataagcag atattaaatg
    44401 aaacaatcac ggcagtaagg agtgtgaact atgttcccga taaaatatat tgacaataac
    44461 cttgtctgga acaaggacaa tgaagtgttt gcctattatg agctggtacc atacaactat
    44521 tcttttctat ccgcagagca gaaatttatc gtgcatgaca gtttccgaca gctaatcgca
    44581 cagtcccgtg agggtaaaat tcatgcgttg cagattgcca cagaaagctc catacgaagt
    44641 atgcaggagc agtcaaagaa actggtaacg ggaaaattaa aggaagttgc ctaccagaaa
    44701 atagacgaac agaccgaagc gttagtatct atgattggga acaatcaagt ggactaccgc
    44761 ttttttcttg gctttaagct catggttaag gaagaacagc tcaatctgaa gaacatcaaa
    44821 aaatcggcgt ggctgacatt caaagagttt ctccatgaag taaaccatac gctgatgaat
    44881 gattttgttt ccatgccgaa tgatgaaatc aaccgttaca tgaaaatgga aaagttactg
    44941 gaaaataaaa tctcccgtcg ctttaaggtg cgtcgcttgg aaatcaatga ttttgggtat
    45001 ctcatggaac atctttacgg cagggacggt atcgcttatg aagattatgc gtaccagcta
    45061 ccaaaaaaaa aattgaacaa agaaacgctg ataaaatact acgaccttat ccgtccgaca
    45121 aggtgtgtga ttgaagaaag ccagcggtat ttacgcttgg aacatgagga caaggaaagt
    45181 tatgtgtcct attttaccgt caatgcgatt gtcggcgagc ttgattttcc gtcaagtgaa
    45241 atcttctatt tccagcaaca gcaattcaca ttccccgttg atacttctat gaatgtagaa
    45301 atcgtggaga accgaaaagc attaacaacc gtacgcaaca agaaaaagga attgaaagac
    45361 cttgacaatc acgcttatca agcaggaggt gaaaccagct caaatgtggt ggacgcttta
    45421 gacagcgtgg acgagctgga aacggactta gaccagacaa aagaaagtat gtataagtta
    45481 agctacgtta tacgggtgtc tgcacccgat cttgacgagc tgaaacgccg ttgtgatgaa
    45541 gtcaaagact tttacgacga cctcaatgta aagctggtac gtcctgctgg ggatatgctg
    45601 gggcttcatt ctgaattttt acctgccagc aagcgatata tcaatgacta tgtgcagtat
    45661 gtaaaatcag acttcttggc agggcttggc tttggagcga cccagcagtt aggggaaact
    45721 acgggtatct atatgggcta ttccgttgat acgggaagaa atgtgtacct gcaaccgtct
    45781 ttagcttcgc agggcgtaaa aggtacagtt accaacgctt tagcgtctgc ttttgtcggt
    45841 tcgcttggcg gtggaaagtc gttctgcaac aatcttctgg tgtattattc ggtgttgttt
    45901 ggcggtcaag cagtcatttt agaccccaaa gccgagcgtg gcaactggag agaaacactt
    45961 ccagaaatcg cccatgaaat caatatcgta aatcttacca gcgataaaga caatgcagga
    46021 cttcttgacc cattcgtgat tatgaagaat gtaaaagacg ctgaaagtct ggcaatcgac
    46081 atcttgacat tccttacggg tatttcctct agggacggcg aaaaattccc cgtgttacga
    46141 aaagcggttc gttccgttac ccagagcgac agtcggggct tgctccatgt aatagacgag
    46201 ctacgccgtg aagatacgcc catatcaaga aatatcgcag accatatcga cagcttcacg
    46261 gactacgact ttgcacatct gctgttttca gacggtacgg tggaaaatgc aatcagcctt
    46321 gataaccagc tcaatatcat tcaagtagcc gaccttgtac tgccagataa ggacacgacc
    46381 tttgaagaat acacgactat tgaattattg tcggtatcta tgctgattgt gattagtacc
    46441 tttgcccttg attttatcca ttcggacaga agtattttta agattgtcga tttggacgaa
    46501 gcgtgggcgt tcttaaatgt ggcacaagga gaaacgctct ctaacaagct ggttcgtgct
    46561 ggacgagcta tgcaggcagg tgtttatttc gttacacaat cttctgggga cgtggcaaag
    46621 gaaagtctga aaaacaatat cggcttaaaa ttcgctttcc gttctactga catcaacgag
    46681 ataaaacaga ccttagaatt tttcggtatc gacaaggacg atgaaaacaa ccagaaacgg
    46741 cttcgtgatt tggagaacgg acaatgctta ttgcaggact tatacgggcg tgtcggtgtg
    46801 gtacagatac acccagtttt tgaagaactg ctacacgcct ttgataccag accgcccgta
    46861 cagagaaatg aggtggagtg atgaaagaaa ggataaaagg tgcgttcaca aaaaggaaga
    46921 tacttcactt tctcaaaatg gctctgttcg tggtggcact ctcccttatc ctgctttcac
    46981 ttttggggac ggtggctcat gcgacggggc ttgtggacga taccataaac gcagaaaatc
    47041 tttactcaaa atatcccctt tccaactacc agcttgattt ttatgtggat aatagctggt
    47101 cgtggcttcc gtggaactgg ctggacggga ttggaaaatc ggtacagtac gggctttact
    47161 gtattaccaa ctttgtctgg acgataagcc tttatttaag caatgccacg ggctatgtgg
    47221 tgcaggaagc ctataaactt gatttcatta acgatatggc agacagtatc ggaaaaagca
    47281 tacagactct tgcaggcgta acacagaacg gcttttcttc tacgggcttc tatatcggtt
    47341 ttctgcttct cattatctta gtggtgggac tttatgttgc ctatacggga ctgataaaaa
    47401 gagaaaccag caaggcactt cacgccgtta tcaactttgt ggtggtattc gtgttgtctg
    47461 cttcatttat tgcctacgct cccgattaca tcaaaaagat aaatgagttt tcatcagaca
    47521 tcagtaccgc ttcacttgac ttgggaacaa aaatcatgct ccccaactct gacagcgagg
    47581 gcaaggacag cgtggacttg atacgggaca gcttattttc tattcaagtg gaacagccgt
    47641 ggttactctt acaattcggg aacagcaacg cagaggaaat cggaacagac cgtgtagaag
    47701 ctcttgtatc ggcaagtcca gaggacgagg acgggaaaac cagagaggaa gtcgtgaaaa
    47761 cagaaatcga ggacaacgac aacaacaatc tgacgatacc gcaggtggta aaccgtttag
    47821 gtatggtgtt tttcctcttg ttctttaact taggtatcac gatatttgta ttcttgctta
    47881 cgggcatgat gttatttagc cagatacttt ttattatctt tgcaatgttt ttacctatca
    47941 gctttttact ttccatgata ccgagctatg aaagcatggc gaagcaggca atcgtaaggg
    48001 tgtttaatac cataatgaca cgggcaggaa taacgctcat tgtaacggtg gcgttcagca
    48061 tttccagtat gttttataac atctccacgg actatccgtt ctttatggta gcgttcttgc
    48121 agatagtatg tttcgctggt atttatatga agctgggcga tttaatgagt atgttctctt
    48181 tgaacgctgg cgacagtcaa aacatgggac gcaggatatt ccgcagacca tatctgttta
    48241 tgcgacatag agctaggcgt atggaaagac ggcttgctgg tgcggttact gctggcggtg
    48301 ttgctggtgc ggtggcaggt agcacgattt caaacagaaa accgacaagg aacacagcca
    48361 caaaagacag tcggggcaat acatctactt ccagtatggg acagcgtgca ggctcaaagg
    48421 tgggtgctgt cttagatacg aaaaataaag tgaaagacaa ggcaaatgct gtcaaagaga
    48481 atatcaagga tatgccgaca cagaccgctt atgcggtgta ttccgcaaag gaaaaggcaa
    48541 agtccagcgt gtccgacttt aagcgtggca tggtgcagga acagcagtcc agacagacgg
    48601 gacgtttgga aaagcaggaa aagcatagac agagtatcgc tgacaagcgt atggagcttc
    48661 aaaaggcaca agaagcaagg caggcacagc gaaaggctga cggatcagcg acaacgggag
    48721 ctacccgtcc ccatgagcga ccagccacag cttcaaagcc gagtgcggaa aaaatgcagg
    48781 aagtcaaacg tcctgccaca gcgaccactt caaaagcaag tgagccagtc aagacaaatg
    48841 ttatcaaaga gcgtccgtta tcttctggtg cttctgataa gaaagcgacc cagtcggcac
    48901 agccagtaca taggcagaat gtagaaaaag tggtatcgca ggaaacacgc cagaattaca
    48961 caaaagaccg caggacaaag gttcagcaga cgcaaaccgt ccaaaagaac cagcagacaa
    49021 cagagaaaac tcgtaacctt gtgatgaaga aaggacagaa gaaaaaatga aactgaaaca
    49081 tatcgctatc attggcactc tgtttcctat cctcttttct ctggtgcttt tctttggtgt
    49141 cctcattagt gcagacagcg acgacgaaaa cagcaatttt tcttctggca ttacgggtat
    49201 gaacttatcc gcagaagtct tgaaacatca gcctatggtg gaaaagtacg ccagagaata
    49261 cggcatttct gagtatgtca atgtgttgct ggctatcatt caagtagaaa gtggcggtac
    49321 ggcagaagat gttatgcaga gttcggaaag tcttggttta ccgcctaatt ccttagatac
    49381 ggaaagctca atcaagcagg ggtgtaagta ttttgcgtcc ctgctttctt cctgcaaaaa
    49441 tcaaggtatc gacgatttga atgtagcgat acagtcttat aactatggcg gtggctatgt
    49501 gggatatgtg gcaggaaaag gaaagaaaca cacctttaat cttgcagaga gcttcgcccg
    49561 tgaaaaatcg ggtggaaaga aagtaaccta caccaacccg atagccgttg cgaagaacgg
    49621 gggctggcgg tatcagtatg gcaatcaatt ttacgtcgaa ttagtcaatc agtatttaac
    49681 tgttccgcag gtatcgggag aactggcaca aaaagtaatg aatgaagcat tgaagtatca
    49741 aggctggaag tatgtatatg gcggtagcaa tcctaacact tcctttgact gttcggggct
    49801 gacgcaatgg tgctatggaa aagctggtgt ttccttaccg agaacagcac aagcacagta
    49861 tgacgccacc caacatcttc cactctcgca ggcaaaggct ggggacttgg tatttttcca
    49921 ttctacctat aacgctggaa gttatgtaac acatgtcggt attcttgttt cgccgacgca
    49981 gatgtaccac gcaggaaatc cgataggata tgcagaccta aataatagtt actggcaaca
    50041 gcacttaatc ggtgcaggac gagtaaaaca atagaaagtg aggataacat tatgtttaag
    50101 aagaataaga aacagacaga aaatgtcaaa gaaaaaaagg tgcgtactgt caaggtaggc
    50161 acacataaga aaaccgtgat tgcgttgtgg gtggtgctta tcgcaagcgt gagctttggg
    50221 gtgtataaga attttacggc tatcgaccag cacacgaccc atgaaaaaga aatcattgaa
    50281 cttcgtttgc aggacaccaa cgggatagaa aatttcgtga agaactttgc gaagtcttat
    50341 tacacatgga gtaacaacaa agaagcgatt gaagcaagga cgcaggcaat cagcggttat
    50401 ctgacaaagg aattgcaaga cttgaatgtt gatacaatca gaacggatat accgaccagc
    50461 tccacagtta cagatgtgat tgtgtggcat atcgagcaat cgggaacgga cactttttct
    50521 gctacctacg aagtagatca gcagataaaa gagggagaac agacaagcaa tgtgaaagcg
    50581 acttatactg taaaagtcca tgtagacgct gacggggata tggtaatcat tcagaaccct
    50641 actcttgcac cagcaatcga aaaatcagac tatgagccta agacaccaga agcagacgca
    50701 agcgtggacg ctgatacggt aaatgacgct accgcatttc tggaaacatt ctttaagctc
    50761 tatccaacag ccacagaaaa agagcttgct tactatgtat ctggaaatgt gattgagcct
    50821 atcggcaggg actaccttta ttctgaactg gtaaacccta tctttacaaa ggacggggat
    50881 aatgtgaaag ttaaagtagc tgtaaaattc cttgataatc agacaaaggc gacacaagta
    50941 tcacagtatg agcttgtgct acataaggat agcaactgga agattgtagg ataaaagaaa
    51001 aaggcttgca gttctgtatt gatttgcaag cctaaatata ttatttatac ttctggaaaa
    51061 tcccgactaa taaagtatct atcgcttcag ctaattcaaa tctaacttta tctgaggcag
    51121 aaaaagcgtt tcctaattgc aaagttgtat aaccgtgaat tattccagta agcatattta
    51181 atatttcaag tgttttgtct ttgttaagac tgcacgattg gataagagta gttaataatg
    51241 aaagatagtt gttaaaaatg gttgctgttt cctctgttcc gtgccacaca gcccattgaa
    51301 ttgtttcata aactccgggg tgttcaatca tatagtttag gtattcgata gaaactaact
    51361 taattgcttc tttccctatt tttccaacgg caattttcat cattctttca ttcatgtcac
    51421 gcataccatt atgagcaact tctaaaagaa gattatctaa actttctatg tgattatata
    51481 aagatggtgt acgaatgttt aatttttgag caacagcttt taacgaaacg ttatttaatc
    51541 ctttttcatc tgctaagtct gatgttgctt ttattactgc ttctttagtg gttttcatag
    51601 ttatgcacct cattcaaaat atcatacaaa cacaattcta gctaattgaa ttagtgtagt
    51661 caataacaca attagaaaat tatgattatt tattgacttt cttaaaattt tgtgtataat
    51721 aggaattgaa gttaaattag atgctaaaaa tttgtaatta agaaggaggg attcgtcatg
    51781 ttggtattcc aaatgcgtaa tgtagataaa acatctactg ttttgaaaca gactaaaaac
    51841 agtgattacg cagataaata aatacgttag attaattcct accagtgact aatcttatga
    51901 ctttttaaac agataactaa aattacaaac aaatcgttta acttctgtat ttatttacag
    51961 atgtaatcac ttcaggagtg attacatgaa caaaaatata aaatattctc aaaacttttt
    52021 aacgagtgaa aaagtactca accaaataat aaaacaattg aatttaaaag aaaccgatac
    52081 cgtttacgaa attggaacag gtaaagggca tttaacgacg aaactggcta aaataagtaa
    52141 acaggtaacg tctattgaat tagacagtca tctattcaac ttatcgtcag aaaaattaaa
    52201 actgaacatt cgtgtcactt taattcacca agatattcta cagtttcaat tccctaacaa
    52261 acagaggtat aaaattgttg ggagtattcc ttaccattta agcacacaaa ttattaaaaa
    52321 agtggttttt gaaagccatg cgtctgacat ctatctgatt gttgaagaag gattctacaa
    52381 gcgtaccttg gatattcacc gaacactagg gttgctcttg cacactcaag tctcgattca
    52441 gcaattgctt aagctgccag cggaatgctt tcatcctaaa ccaaaagtaa acagtgtctt
    52501 aataaaactt acccgccata ccacagatgt tccagataaa tattggaagc tatatacgta
    52561 ctttgtttca aaatgggtca atcgagaata tcgtcaactg tttactaaaa atcagtttca
    52621 tcaagcaatg aaacacgcca aagtaaacaa tttaagtacc gttacttatg agcaagtatt
    52681 gtctattttt aatagttatc tattatttaa cgggaggaaa taattctatg agtcgctttt
    52741 ttaaatttgg aaagttacac gttactaaag ggaatggaga taaattatta gatatactac
    52801 tgacagcttc caagaagcta aagaggtccc tagcgcctac ggggaatttg tatcgataag
    52861 gggtacaaat tcccactaag cgctcgggac cccttgtagg aaaatgtcct aagtgtggca
    52921 acaatattgt attaaaaaaa tcgttttatg gttgttcaaa ttatcctgaa tgtaagttta
    52981 ctttagctga acattttaga aagaaaaaac taaccaaaac gaatgtaaaa gaattactgg
    53041 agggaaaaga aaccctggta aaaggaatca aaaacaaaga gaaaaagccc tacaatgccg
    53101 ttgtaaaaat tggggaaaag ggatatattg attttatctc tttttcaaaa taaacataaa
    53161 agccctttaa agagggcttt tatatattaa tcacaaatca cttatcacaa atcacaagtg
    53221 attaatcact tgtttattaa gatattaaaa gctataattt aaataaagcg tgaattttat
    53281 gacacaaaaa gaggggggag aaacttggaa ctagcattta gagaaagctt aaaaaagatg
    53341 agaggtacca aatcaaaaga aaaattctcc caagaattag aaatgagtag atcaaattat
    53401 tcacgaatag aatcaggaaa atcagatcca accataaaaa cactagaaca aattgcaaag
    53461 ttaactaact caacgctagt agtggattta atcccaaatg agccaacaga accagaacca
    53521 gaaacagaac aagtaacatt ggagttagaa atggaagaag aaaaaagcaa tgatttcgtg
    53581 tgaataatgc acgaaatcat tgcttatttt tttaaaaagc gatatactag atataacgaa
    53641 acaacgaact gaataaagaa tacaaaaaaa gagccacgac cagttaaagc ctgagaaact
    53701 ttaactgcga gccttaattg attaccacca atcaattaaa gaagtcgaga cccaaaattt
    53761 ggtaaagtat ttaattactt tattaatcag atacttaaat atttgtaaac ccattatatc
    53821 gggtttttga ggggatttca agtctttaag aagataccag gcaatcaatt aagaaaaact
    53881 tagttgattg ccttttttgt tgtgattcaa ctttgatcgt agcttctaac taattaattt
    53941 tcgtaagaaa ggagaacagc tgaatgaata tcccttttgt tgtagaaact gtgcttcatg
    54001 acggcttgtt aaagtacaaa tttaaaaata gtaaaattcg ctcaatcact accaagccag
    54061 gtaaaagtaa aggggctatt tttgcgtatc gctcaaaaaa aagcatgatt ggcggacgtg
    54121 gcgttgttct gacttccgaa gaagcgattc acgaaaatca agatacattt acgcattgga
    54181 caccaaacgt ttatcgttat ggtacgtatg cagacgaaaa ccgttcatac actaaaggac
    54241 attctgaaaa caatttaaga caaatcaata ccttctttat tgattttgat attcacacgg
    54301 aaaaagaaac tatttcagca agcgatattt taacaacagc tattgattta ggttttatgc
    54361 ctacgttaat tatcaaatct gataaaggtt atcaagcata ttttgtttta gaaacgccag
    54421 tctatgtgac ttcaaaatca gaatttaaat ctgtcaaagc agccaaaata atctcgcaaa
    54481 atatccgaga atattttgga aagtctttgc cagttgatct aacgtgcaat cattttggga
    54541 ttgctcgtat accaagaacg gacaatgtag aattttttga tcccaattac cgttattctt
    54601 tcaaagaatg gcaagattgg tctttcaaac aaacagataa taagggcttt actcgttcaa
    54661 gtctaacggt tttaagcggt acagaaggca aaaaacaagt agatgaaccc tggtttaatc
    54721 tcttattgca cgaaacgaaa ttttcaggag aaaagggttt agtagggcgc aatagcgtta
    54781 tgtttaccct ctctttagcc tactttagtt caggctattc aatcgaaacg tgcgaatata
    54841 atatgtttga gtttaaaaac attttaaaat actaattaga ttagttaaat gactatttga
    54901 aatagtattt tgaggagtga ttatatgtgt acaagatttg tttacaatgg tatagataaa
    54961 attgttggtt ttaattttga tattgacctt tctgtatggg atcatactgt aattaccgaa
    55021 gaaaatagat tttatattgg tattaaaatg cctgacggtc tgtatcattc atttcatggg
    55081 ataaataaaa atggtaatgt aggaacactt ctttatgttc atggtaatga aaatgcaagg
    55141 tatatagaaa gcgaggattg tattacaata tctgaattaa cagaaaaatt cattaaggca
    55201 gagatttctt ttgataaagc cttggacatt gttaaaaaga aaaaaattat ttatgcacca
    55261 gatgctacta tgcaagctat gctttctgat aaaaaaggac gagttttaat tattgaacct
    55321 ggaattgggt atagatatga acaagaaaat ttttcactta ttacaaatta ttctattcta
    55381 aaaccagata taacaaagcc gtacattgtt tctggggata caagatacga agtggctaaa
    55441 gagttattgg caggatatga taaagatttt tcagtaaatg acgcatttaa agtattaaaa
    55501 tctgtttctc aaaaagactt gtgggcaact agggtttcat ttgtatattc tacagaaaaa
    55561 aataaagttt attatgtctt gaacaatgat tttagtaatg tatttgaatt tcagttttaa
    55621 tactaatgaa tttataaatt tgcaattatg ataagaaagg ttattatgat aggactaaaa
    55681 aagcgagata taaaaaaagc gttgaaagct ggtgcaaaag ctggcggtgt atcattggct
    55741 gatgttcggg cagatattga agcgacgatt gatgaagcta tgaatagcac cgccccagaa
    55801 gtgtaggcaa atttcaaaaa atattttggt aataaacgcc ctaccccaga agaatatatt
    55861 tacaagatta ccaaaaagac aaagatttga aaaaaggctt gctccataca tagtgtatga
    55921 tctgcaagcc ttaatctatt tcagaggaaa tttaacagta aaagtagcac ctccaccagc
    55981 agtatcattg ataatgataa taccgttcag catttgagtt aattctttgg cgatacttag
    56041 tcccagtcca aaattcgatt tgttcgtatg ggacttgtcg ccactataaa atcggtcaaa
    56101 gatatactgc ttatcttcat cagaaatgcc ttgcccgtgg tctaccacag aaaaagcaat
    56161 atttttttcg gtggcgatta cttctatctc tattaaagaa ttattcttgg aatgttgaat
    56221 ggcattatcc ataaagacac acaagatttg aaataatcgg tctttgtcgg taaacatagc
    56281 aggataactt tcctcggata aatgcagttt tagttctaaa ttctgcttca tgcagacggg
    56341 ttcgtaggtt tcatataacg taatgagcaa ggtatctaca ttgattgtgc ttttatgcaa
    56401 tgtccatgtt ttagcgtcgg aagaagccaa aagcaacata tctttgacta aacgggataa
    56461 ccgcatacat tcaaaatcta tggtctgtac ggcttgcttt gcctgctcgt ttaaggaaac
    56521 attatcaaga agcatatccg tgttggaaat cataacagca agtggagatt ttaattcatg
    56581 ggacgctgtt gcaacaaaat ctttttggct ttgcagtatt cgttccgttg gagcaaacga
    56641 ctttttcagc agataacggg tcagcacgat aacaacgata caagccaaaa accagataag
    56701 aagatatata ggcaatgttt tttgtaaaat atccgtcaaa ctggctgtct gataaagaaa
    56761 ggttgcatga tacacggtat catttgctgt cctaattgta gcaggaataa caaaataagt
    56821 atcgtgatgt gttcctctta tttccagaaa accgccttgt gaagttgtgc tgttttctat
    56881 ttgtgataat ggttgtgtag aaatctgctt ttctacatca tgcaacagat tgtccgcaga
    56941 agttggaaat gggaaatcac tctgataaat ggtattcccc cttgtatcag taattaaaga
    57001 aaaaatatga taactctctt cgtaggtttt gagtgctttg tccatatccg aagaagcact
    57061 ttccacttga taaatcagca aggttgtcaa tctctgaaat aaggtgcttt cgttgatttt
    57121 ctctgtatga actgtgttcg caacgacaaa ggaaatcaca agggtaataa tcagcataac
    57181 agaacttgca aacagaatat gaagttttcg gtataagtta tttaacatgt ttctttctcc
    57241 agtttgtacc ctgcaccgta gaccgttgtt attttacagg aactttttaa ttcttttagg
    57301 cgttttcgca gaaaagaaat gtaactgtct acattgccag tttctacctc ggaagaactg
    57361 ccccagattt taaggattag ctgttcacgg gaaaatagtg tttctgggtt ctgcataaat
    57421 acaaaagtca actcggtttc ttttgaagtt aataaaagag aattgacggg tgtagataag
    57481 gttcggctgt ctttatcgaa agttaaatct ccatattcta atttggaaga taactggata
    57541 ttggcagggc gtcttgttaa tgcccgaact cttgcaagca attctttgat atgaaatggt
    57601 tttactaaat aatcatcagc accgccgtct aaaccctcaa cccgattgtc aagggtactc
    57661 atggcagtaa tgataaggat aggaatagaa attccttttt tacgcataga ttttatgatt
    57721 gtcaaaccgt caataatcgg taacatacgg tctacaatgg cgaggtcata agcatagtct
    57781 gtatttaagg catacagcat agcagtttcc ccgtcattgc aacaatcaac catatagttt
    57841 tctttttcca gcgaaatttt tatattttta cataactcta aatcatcttc cagaagaagt
    57901 attttcataa tgtatcaatc cttttctata tatcatcttg gacattagca gtccaagaag
    57961 ctttaattat agacagtata acagaaaagt ctgtaaaaat cctctaaaaa atgatgatga
    58021 ttttcttgct tttttacagg atttttagaa tggtttgctt ttacaatagt ggcatatcga
    58081 ataagaaagg tggaatacaa aatgaaaaaa acaaacatca gtaaatttgt agcagttgga
    58141 ttatgtatct gtgcattgac ggggtgtggt gcaagtccag atgagaagcc agatatgtct
    58201 aatcctattg tcaattctaa tacgaatgaa gaaaatgcaa atggctcttc agaaaataaa
    58261 gaaaacgaca tattagagtc tgctaatttg ataggaagtg ttttggaatt tacagacaat
    58321 ggttgttccg taagtcaagc aaaagaaatt gaggggggag cagggataaa atcagaagca
    58381 ccgggactgg aaaataaaga caatgctgtt tctgtaacct ataacccaga ttgtgaattt
    58441 gtcattgcca cagtaaatgc acagtctggt gttacaaatg taacaacggg ttctatatcc
    58501 gatgtaaaaa aacaatctga agtatatctt tatggagaat ttgcagacac acttcatttc
    58561 aatgcaacaa aggttgtcat agcccgttgg gaatagaggt gtgaagtatg aagttttatc
    58621 aacttggttt tcgctattta cagcgaaaaa aaggaaaaac cattcttttg ttgattgttt
    58681 tgatacttgt aaacagtatg attttaggta caagcatgat tttaaggact acaaatgagt
    58741 ccaaacaagc catgcaggaa aagacaaatt ctaagattgt agctgaaatt acaagtaagg
    58801 acagcaagat aacagagaat gaagtaaaca agattgaaac gctggaagat gtttcagcta
    58861 tcaaccgtat cggcaggcaa gatgtatttc cagctagttt tgctcccgtt acgctcaata
    58921 cttctacgaa tgaggaaaat ttgaaaatag cactgctttc ctatgatgat ttggaaaagg
    58981 acagcccttt ttcagaaatg cagtaccgct tagcttctgg cgattatatc aagcgtgaga
    59041 aaaagggtgc tgttatcaat gcgaaccttg caaatcaaaa tgagctaaaa gttggagata
    59101 cgattgaatt aagtacagaa aacggaacaa aagtatctgt tcagattatt ggaattttca
    59161 tgtccgcagg aaatgcggaa aaagaccagc cgtcagaaac taccgcagtc aatcgaatag
    59221 aaaatcaaat ctttattgac aacagtactt ataaagaatt gttcaaagaa gctgaatttg
    59281 aaaaaatctg catttactca aaaagaccag aaaaattaga tgtgctggaa accagcctgc
    59341 aaaaaatatt cggaaatgat gtagcactta gcacgtctga taccctttat caacagatgt
    59401 ctgctccatt agagcaaatc agtaaggtgg caaatcttat gctggtactt acattggtaa
    59461 ctggtactgt tgttgtttcc ctgctgttat gtatgtggat gcggacaagg caaaaagagg
    59521 tggcaatctt tatgagcctc ggcaagacaa aaagtgaaat tttcctgcaa actttattag
    59581 aagcaggcag tgtatttaca ctttcggttt taggagcaac agccattggt aaattgttct
    59641 cgggcgtttt gcaaaacgtc attaccggtt cagaaacagt aacagaaaat ctgaaagtgg
    59701 ttttgcagat acaagatatt ggaatgttgt tccttttagg cggtgcagtt attttggtgg
    59761 cattgtgctg ttccattctt ccgatattac gagcaaaccc aaaagatata ttagcaaaaa
    59821 tggagggata gtacatgaat ttttttggat tggcaaggcg ttctgtgttc agaaagcccg
    59881 taaaaagtat tctcttattg ttgattgttt ttgcaatcag taccttgctt cttgcaggtg
    59941 tggcgagcaa aaatgccagt attgaggtgc aggacaaaac cagacaagcc ataggtgcag
    60001 gctttctttt agaaagaaat gcagagtacc gaacaaagcg agttcgtgaa tactcagaaa
    60061 agattggtaa tgataaggaa ggtagttttg gtggctacca tcaggaaaaa gagattatca
    60121 atggtgtgga gacttggaca ggctggacaa caaatgaatt tgaaagctta gatataaaag
    60181 acattgagaa attggcaaaa gcaaaaggaa ttgctgatta caatattaca acagtaacaa
    60241 ctcccgtaaa ccctgtaaat ttcaaaagga ttgaagataa agatgtagac cagaatgcag
    60301 atgttggcgg tgtaagttta attggaaaca aagatatgaa actagacaga aatgttttat
    60361 ctggaaacct gcatatcaaa gagggacgaa tgataacccc agaggataaa gatatgtgtg
    60421 tcatttcaga ggaactggca aagcaaaata atctgaaaat cggcgataag atttctttta
    60481 atgattacca cgatactgaa aattcaaagg tatcagaagc tgagattgtt ggaatttatc
    60541 aagtggatca aaagatgtcc ccacttatgc agggagatac ttaccgttcg gaaaatgtaa
    60601 tatttacaga tttgagattt ccagaaaagg cagagggtga aacaagtcca ttatatgaaa
    60661 gagcctattt caaagtggaa gatgtggaag cttacgacga agtaaaagaa aatctgcaaa
    60721 aagtagacat caattgggag caatatgatt tgattgacaa taacggaaat tccgaaacca
    60781 tgtcctcaaa cttcaatgat ttagcaaaag taagcgaaat gatgatattg gtaatctctg
    60841 ttgcaagttt tgttatcctt gttttagtat ttctgttctg gctgaaaaat cgagtgcagg
    60901 aagtcggtat tttcttatct ctcggtgttc cgaaatttag aattatcgga caaatttgga
    60961 gcgaagcgat tatgattact gttctttccc ttatgttatc ctttgctgtc gctcctgctg
    61021 tttccaaagt aacggcaaat tatctggtat cacagcaggt tcagcaaatg caagaggaag
    61081 aaaagaataa tgagggaaaa gtatccacag aatacgttgc accaaagcag gacgtgcaga
    61141 gtatcagcgt agaggttaca ccagaaatgt atctgttgga cggtgtaagt gttcttgtgt
    61201 tgataacggc ttctgttctg gtatctggaa ttgtaatact aaagagaaac ccgaaagata
    61261 ttttatcgga aatgagttag gaggacgacg aaaatgttag aagtaaagaa tgtaagctat
    61321 gcttacaaaa caaaaaaaga taaaaccatt ttgaataatg tatctgctac tttcgaggag
    61381 ggtatctttt ataccattat cggtccgagt ggtgcaggaa aaacaacact cttatcgttg
    61441 ttagcaggct tagatacagc agtaaaaggg actgtccttt gcaatggcga ggatattaca
    61501 aaaaaagggc tgaattacca cagaaagcat aatatctcat tggtatttca aaattataat
    61561 ctgattgatt atttgacaac ggttgaaaat gtcaaattag gtggtagtgg aaatgctgaa
    61621 aaattattgg aagaagtcgg tattggaaaa gaatactggc agagaaatgt attgcaacta
    61681 tctggcggac agcaacagcg tgtagcgatt gcaagagcat tagccagcga cgctcatgta
    61741 cttttggcag atgaaccgac gggaaatctt gatgaaacta ccgctgatga aatcattgct
    61801 ttgctgaaaa agactgcaca tgaattagga aaatgtgttg ttgtggttac acacagtaag
    61861 catttggcag aagaagccga cgaaatctta gaaattaaaa acggtgcaat ttcttttctg
    61921 tctgaataaa caagaatagt gccgtaaagg agctgtcatt atggaatatt ttagatatac
    61981 ctcgacacaa tcaatttgac cctaacggca ttgttataag aactaaatac aatacagttt
    62041 caaaggctcg tacagactat atgttttgtg cgggcttttt tcatgccaga aaaaaatttt
    62101 ttaagttttt tttgattttg gttacgctgt accccacttt caacgcggta tatatgaaaa
    62161 ggggcagaca cctcttttcg actagcgaaa ggaggtgagg aaaataaaac cgtcagaact
    62221 acaagaaaaa acctgtcatc aattcgattg tgctattaaa acagttatac gtcatagagc
    62281 gattgacttc tatcgagcga tacgtcgttc agagaaaaaa gaaatgccat tcgccgaaat
    62341 tatggacgac ctcttaaatt ccataggcac agaagataca tattctacgg attatgttgc
    62401 agtatttgaa gtctgtggcg aaaaagtgtc aatcgaagat gaacaactgg ctcgtgcatt
    62461 gaaagctatt gaagaacgaa agcgtaatat cgttttacag tattttttca ttggggacac
    62521 ggacacttat attggaaaaa tgcttgactg ttccagagct aatgtaacaa aatgcagaat
    62581 acaagcactc gacaagctaa agcaactgat tgaggaggaa aaagagaaat gccaaaagag
    62641 ctgacaccga ctttcacggt tatttccaaa gcatgcgacg gcgacgaaac agctatttca
    62701 aaaatcttgg agttttacga cccatttatc aatcagtgct gtatgcgtcc gttttacgat
    62761 gataacaaca acttgcgtct tgcggtagat ttggaaatga aaggttttat caaagaagcg
    62821 attattcgta aaatcttaaa ctttgatatt aaacgcttct aattcatatc gggattgatt
    62881 atgcccgtct ggtctttgac aactgaataa agcagacaga tacgtttgtg agatagcaag
    62941 ccacggggac tgtacgccat gacctttcca aaagaaagcg agcgacccat gcagtgatcc
    63001 gagagcgacc gttggaaaag tcgctttgcc acgacctatc ctcacagaat aatgatacgt
    63061 ccgcatggtg cggttctgcc cacaggaatg ggaatggttg agataccaac ggagctttcc
    63121 aaagccgtct gcctgcttgt aaaaaatgac acacagtaaa gggggtgcat agattatgaa
    63181 caatactgat gtgcctatct gggaaaaata tactctgacg attgaagaag cgtctaaata
    63241 cttccgcatt ggcgaaaaga aattgcgtaa attagccgaa gaaaatattg acgctggctg
    63301 ggttatcgtg aacggtaatc gtattcagat taagcgaaaa caatttgaaa aaatcataga
    63361 tacattggac gaaatctaat gtcattgagc cgtagatatg gtataataag gtatagcgta
    63421 tcacggctca ttccatgacg gaaaggagct ttacactatg tctaatgtaa aacgaaaaga
    63481 cagtaaaaat cgcaatttgc gtaatggaga gagccagcga aaagacggaa gatacgttta
    63541 taaatatacc gatatatacg gaaagccaca atttatctat tcttggaaac ttgtaccgac
    63601 agacaagaca cctgctggaa agcgtgatga tatttcattg agggaaaaag aagcacagat
    63661 aaaaaaagac cttaacgacg gtatcgacac agtcggcggt aaaatgacag tctgccagct
    63721 ctacgacaag aagaacagcc aaagaaagaa catcaagagg gctactgaaa aaggacgaca
    63781 gtatcttatg aacgctctga aaaatgaccc attgggtatg agggcgattg atactgttaa
    63841 gcagtcggac gctaaagaat gggctatcag aatgagtgaa aaaggatatt cctataaaac
    63901 gattgataac tataagcgtt ccttgaaagc ttcattttac atggcgatac aagacgactg
    63961 tatcagaaag aacccatttg actttaagct aagtgatgtt ctggaagatg atacggagca
    64021 gaaagttatc cttacaccag agcaggaaga acgcctgctt gcctttatgg aaaaggacaa
    64081 gatttacagc aagtattatg atgaggttgt gcttctgctg gaaacgggac ttcgtatttc
    64141 tgaattttgc ggattgacga cgcatattga tatgcagaac agaatactca atatagacca
    64201 ccagctattg aaagatagcg aaatgggcta ctatattgaa acaccaaaga ccaaaaacgg
    64261 aaaacgggaa cttccattga cagaacgggc ttatcaagca atccaaagaa tactaaagaa
    64321 cagaggaaag gcacaaccgc tgattgtagg tggttacagc aatttcctat tcctaaatcg
    64381 tgagggcttg cctaaagttg caggaaacta tgagggcatg gtgcgaggac tgattaagaa
    64441 gtataacaag tatcacacgg acaagttacc gaacatcacg ccacattcat tcagacatac
    64501 ttattgtacg aatatggcaa acagaggaat gaacccaaac actctgcaat atctcatggg
    64561 acacgctaac ataaccatga cacttggcta ttatgcacac ggcacatttc aatctgcaaa
    64621 agcagaactg gaaaggctgg cttgttaata tcggagctta tatttactac tcatttacta
    64681 cttttggttg cattttcatg ctggtaaatg ccagcttatg caaggtatct tccgaaaaga
    64741 aaataccgat aaagccctaa aatacgggat atatcggcat ttaccaactt atgaaaagat
    64801 aatcagaaat ttagtaagtt tttataaaag aaaaatacac atctataaat tataaatgtg
    64861 tattctgtac cattactaat aatatattat acttttttac aaatttctaa ttatttataa
    64921 ctattcaaaa ataaaattca tataaaataa ttctattgta caattgaaac tttaataatg
    64981 tctccatttt ttctctccaa gtgaactact tctccagtta aatcatagtc aaatgcctta
    65041 actaatattt cagtaacttt tttaccatct actacatcat cttttccatt aaataaatcc
    65101 aaagcattat tctcaatcat tctctttgca aaatttacag gtaactttat atgtatttta
    65161 tcgcctgtat gtgataagac tcttattctt aaaaactttt ctaaattgtt tcttggtatt
    65221 tgttttgatg ccatgctatt aaatcactct cctttatttt ttatttaata ataaatttta
    65281 ttcttaaaaa tatct
//
LOCUS       DAEPXW010000007        63090 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.007, whole genome shotgun sequence.
ACCESSION   DAEPXW010000007 DAEPXW010000000
VERSION     DAEPXW010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 63090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63090
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.007"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            182..1057
                     /locus_tag="KRM55_000445"
     CDS             182..1057
                     /locus_tag="KRM55_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HBH1592716.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            1075..2565
                     /gene="cls"
                     /locus_tag="KRM55_000446"
     CDS             1075..2565
                     /gene="cls"
                     /locus_tag="KRM55_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH1592717.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            2758..3042
                     /locus_tag="KRM55_000447"
     CDS             2758..3042
                     /locus_tag="KRM55_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBH1592718.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            3075..4703
                     /gene="groL"
                     /locus_tag="KRM55_000448"
     CDS             3075..4703
                     /gene="groL"
                     /locus_tag="KRM55_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBH1592719.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            4965..5705
                     /gene="larB"
                     /locus_tag="KRM55_000449"
     CDS             4965..5705
                     /gene="larB"
                     /locus_tag="KRM55_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBH1592720.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            5789..6523
                     /gene="larC"
                     /locus_tag="KRM55_000450"
     CDS             5789..6523
                     /gene="larC"
                     /locus_tag="KRM55_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBH1592721.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            6553..6972
                     /locus_tag="KRM55_000451"
     CDS             6553..6972
                     /locus_tag="KRM55_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBH1592722.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      7032..7133
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            7354..8889
                     /gene="guaA"
                     /locus_tag="KRM55_000452"
     CDS             7354..8889
                     /gene="guaA"
                     /locus_tag="KRM55_000452"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBH1592723.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            9428..10858
                     /locus_tag="KRM55_000453"
     CDS             9428..10858
                     /locus_tag="KRM55_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1592724.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVSGSSMDSYFSARYKDID
                     NNTERYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVGKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(11006..11881)
                     /locus_tag="KRM55_000454"
     CDS             complement(11006..11881)
                     /locus_tag="KRM55_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1592725.1"
                     /translation="MINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQA
                     ETALFDRLPRGVCLTRCGISLLEEARSILTACRNLDKRISRLEECTPINIVSSITIAS
                     FLLPPILSRLKNSFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLG
                     SYKLCVACAPTFPLSKQALSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPVWE
                     SVNSFALIKAAEAGLGITILPENLLLDSLFHKKLRLIKLDGIDMENKMLAILHKDKNI
                     TQPLKIILDNISNVL"
     gene            12001..12564
                     /locus_tag="KRM55_000455"
     CDS             12001..12564
                     /locus_tag="KRM55_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1592726.1"
                     /translation="MNQSRKTYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKQFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCIAAIIPPLVILGLVSAF
                     YTTFISNAIVTAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSAMIPIAFFANFVM
                     SINVIFILSVCCFVCVMQAFYKKRENK"
     gene            12561..13127
                     /locus_tag="KRM55_000456"
     CDS             12561..13127
                     /locus_tag="KRM55_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1592727.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     TLLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(13256..13492)
                     /locus_tag="KRM55_000457"
     CDS             complement(13256..13492)
                     /locus_tag="KRM55_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592728.1"
                     /translation="MLECFIAEDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(13802..17230)
                     /gene="uvrA"
                     /locus_tag="KRM55_000458"
     CDS             complement(13802..17230)
                     /gene="uvrA"
                     /locus_tag="KRM55_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1592729.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTITIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSFENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEEIRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAKTPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            17549..19783
                     /locus_tag="KRM55_000459"
     CDS             17549..19783
                     /locus_tag="KRM55_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1592730.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLKGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSDKESMNEILNIDNFNGEGTIEIINSKGKLLFIGKNTELIKDLSHKYKDSADEP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            20039..22069
                     /locus_tag="KRM55_000460"
     CDS             20039..22069
                     /locus_tag="KRM55_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1592731.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDDQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            22066..22518
                     /locus_tag="KRM55_000461"
     CDS             22066..22518
                     /locus_tag="KRM55_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1592732.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            22520..23575
                     /locus_tag="KRM55_000462"
     CDS             22520..23575
                     /locus_tag="KRM55_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBH1592733.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     IGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            23642..23950
                     /locus_tag="KRM55_000463"
     CDS             23642..23950
                     /locus_tag="KRM55_000463"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBH1592734.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            24054..25319
                     /locus_tag="KRM55_000464"
     CDS             24054..25319
                     /locus_tag="KRM55_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBH1592735.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            25407..26123
                     /locus_tag="KRM55_000465"
     CDS             25407..26123
                     /locus_tag="KRM55_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1592736.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(26318..26611)
                     /locus_tag="KRM55_000466"
     CDS             complement(26318..26611)
                     /locus_tag="KRM55_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBH1592737.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIHQLTCSYKESQNVID"
     gene            complement(26617..26832)
                     /locus_tag="KRM55_000467"
     CDS             complement(26617..26832)
                     /locus_tag="KRM55_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592738.1"
                     /translation="MRILSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            complement(27377..27889)
                     /locus_tag="KRM55_000468"
     CDS             complement(27377..27889)
                     /locus_tag="KRM55_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1592739.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKELSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            28339..28815
                     /gene="purE"
                     /locus_tag="KRM55_000469"
     CDS             28339..28815
                     /gene="purE"
                     /locus_tag="KRM55_000469"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBH1592740.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            28821..29519
                     /locus_tag="KRM55_000470"
     CDS             28821..29519
                     /locus_tag="KRM55_000470"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH1592741.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            29531..30898
                     /gene="purF"
                     /locus_tag="KRM55_000471"
     CDS             29531..30898
                     /gene="purF"
                     /locus_tag="KRM55_000471"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBH1592742.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            30892..31968
                     /locus_tag="KRM55_000472"
     CDS             30892..31968
                     /locus_tag="KRM55_000472"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBH1592743.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            31962..32555
                     /locus_tag="KRM55_000473"
     CDS             31962..32555
                     /locus_tag="KRM55_000473"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBH1592744.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            32548..34080
                     /gene="purH"
                     /locus_tag="KRM55_000474"
     CDS             32548..34080
                     /gene="purH"
                     /locus_tag="KRM55_000474"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBH1592745.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAVVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            34091..35341
                     /gene="purD"
                     /locus_tag="KRM55_000475"
     CDS             34091..35341
                     /gene="purD"
                     /locus_tag="KRM55_000475"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBH1592746.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            35366..39172
                     /locus_tag="KRM55_000476"
     CDS             35366..39172
                     /locus_tag="KRM55_000476"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBH1592747.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLKTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKETSIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            39378..40250
                     /gene="rfbD"
                     /locus_tag="KRM55_000477"
     CDS             39378..40250
                     /gene="rfbD"
                     /locus_tag="KRM55_000477"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBH1592748.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            40359..41228
                     /gene="rfbA"
                     /locus_tag="KRM55_000478"
     CDS             40359..41228
                     /gene="rfbA"
                     /locus_tag="KRM55_000478"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBH1592749.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            41277..41834
                     /gene="rfbC"
                     /locus_tag="KRM55_000479"
     CDS             41277..41834
                     /gene="rfbC"
                     /locus_tag="KRM55_000479"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBH1592750.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            41872..42855
                     /gene="rfbB"
                     /locus_tag="KRM55_000480"
     CDS             41872..42855
                     /gene="rfbB"
                     /locus_tag="KRM55_000480"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBH1592751.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            42885..43553
                     /locus_tag="KRM55_000481"
     CDS             42885..43553
                     /locus_tag="KRM55_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH1592752.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            43562..43990
                     /locus_tag="KRM55_000482"
     CDS             43562..43990
                     /locus_tag="KRM55_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBH1592753.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            44014..44328
                     /locus_tag="KRM55_000483"
     CDS             44014..44328
                     /locus_tag="KRM55_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH1592754.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            44480..44755
                     /gene="flgM"
                     /locus_tag="KRM55_000484"
     CDS             44480..44755
                     /gene="flgM"
                     /locus_tag="KRM55_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBH1592755.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            44760..45176
                     /locus_tag="KRM55_000485"
     CDS             44760..45176
                     /locus_tag="KRM55_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBH1592756.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKKTTTYNSYGNIRK"
     gene            45194..46504
                     /gene="flgK"
                     /locus_tag="KRM55_000486"
     CDS             45194..46504
                     /gene="flgK"
                     /locus_tag="KRM55_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBH1592757.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            46523..47455
                     /gene="flgL"
                     /locus_tag="KRM55_000487"
     CDS             46523..47455
                     /gene="flgL"
                     /locus_tag="KRM55_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBH1592758.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            47471..47863
                     /locus_tag="KRM55_000488"
     CDS             47471..47863
                     /locus_tag="KRM55_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBH1592759.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            47857..48069
                     /gene="csrA"
                     /locus_tag="KRM55_000489"
     CDS             47857..48069
                     /gene="csrA"
                     /locus_tag="KRM55_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBH1592760.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            48091..48486
                     /gene="fliS"
                     /locus_tag="KRM55_000490"
     CDS             48091..48486
                     /gene="fliS"
                     /locus_tag="KRM55_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH1592761.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            48486..48842
                     /gene="fliS"
                     /locus_tag="KRM55_000491"
     CDS             48486..48842
                     /gene="fliS"
                     /locus_tag="KRM55_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH1592762.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQNAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            48863..50386
                     /gene="fliD"
                     /locus_tag="KRM55_000492"
     CDS             48863..50386
                     /gene="fliD"
                     /locus_tag="KRM55_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBH1592763.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSINSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKFANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKSKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRAFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            50389..50724
                     /gene="fliT"
                     /locus_tag="KRM55_000493"
     CDS             50389..50724
                     /gene="fliT"
                     /locus_tag="KRM55_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBH1592764.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYINISSKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            50826..51698
                     /locus_tag="KRM55_000494"
     CDS             50826..51698
                     /locus_tag="KRM55_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HBH1592765.1"
                     /translation="MRVNTNVSALVANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSLQSSNETN
                     TAEERQKVADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTTN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNVDGASGTDAAKQMVSSLDMALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            51791..53932
                     /locus_tag="KRM55_000495"
     CDS             51791..53932
                     /locus_tag="KRM55_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1592766.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TINISRKYTENVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLESAPGYLITSLVKTYLYLGKHKKCEKLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRQNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYFYIMYSYKYIRYIYSNLSDFELKKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILICELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMLENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            53956..55833
                     /locus_tag="KRM55_000496"
     CDS             53956..55833
                     /locus_tag="KRM55_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1592767.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKRQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSSINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIADIEKVKLDYKKDFFDYIILGDILEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMVNLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEIFCFIEGKKY
                     E"
     gene            55826..57940
                     /locus_tag="KRM55_000497"
     CDS             55826..57940
                     /locus_tag="KRM55_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH1592768.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVANINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASAILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAIDDSGGEVISLDLISDDYLKRAMALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYMESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIKRYNTSEFDRDKIKEKQSEIKHFVIDKHCIEIKNYIDKIYNEANHHKVKYNLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            57949..58944
                     /locus_tag="KRM55_000498"
     CDS             57949..58944
                     /locus_tag="KRM55_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HBH1592769.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNSIT
                     NKLEIYLREQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            59036..60268
                     /locus_tag="KRM55_000499"
     CDS             59036..60268
                     /locus_tag="KRM55_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBH1592770.1"
                     /translation="MKRLMILGSIKYFENIVISAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQRLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIELYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            60288..61232
                     /locus_tag="KRM55_000500"
     CDS             60288..61232
                     /locus_tag="KRM55_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HBH1592771.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            61326..61733
                     /locus_tag="KRM55_000501"
     CDS             61326..61733
                     /locus_tag="KRM55_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HBH1592772.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKVIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            61820..62911
                     /locus_tag="KRM55_000502"
     CDS             61820..62911
                     /locus_tag="KRM55_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBH1592773.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
BASE COUNT        24977 a         6665 c        11241 g        20207 t
ORIGIN      
        1 tagaaattca ttttttattt aaggtaaaaa tttaaagtaa aatattattt tacataataa
       61 taaccttata aattttgaaa ttacttatct ttgtgttaaa ataagtaaaa tgcacatatt
      121 agagctaagt ttttaagtaa ataaacaaag tgaaaatata aatattaagg agatttggta
      181 tatgaatgtt tatgaaaaag gtaatggagt tatactagaa ggagtaacag attttgaccc
      241 agtacatata tttgagtgtg gtcaatgttt tagatggcac aaacaagaag atggctcata
      301 cactggagtt gcaaagggga gaatattaaa tgtcaaaaaa gagaatgata aaatatattt
      361 aaataatact aatttaaagg agtttaacag catttggtat aattactttg atttaggaac
      421 tgattataca gaaataaaga ataagctaaa aaatatggat gaatatttaa ataaggctac
      481 tgaatttgga tggggaataa gaatattaag acaagatgga tgggaaatgc ttatatcatt
      541 tataatttcc tctaataata ggattcctat gatacaaaga gctatagaaa atttatcaag
      601 aaagtttggt aagtatatag gtgaatatga aggcaatgaa tactatgcat tcccaacacc
      661 agaagaacta aataaggcct cacaagagga aataagagca tgtcaaacag gttttagaga
      721 taagtacata aaaagtacta cacaggcagt tatagagaat aatgatgagg tatctgaata
      781 tacaaattta agtacagagg attgtagaaa agagctttta aaatttaatg gagtaggacc
      841 aaaagtatgt gattgtattg cattatttgg tatgcaaaaa tatgattctt ttccagttga
      901 tgtttgggtt aagagagtta tgcaagaatt ttatatagat gaagacatga gtttacctaa
      961 aatgagaacc tatggaatcg ataaatttaa agaaatgtct ggatttgctc aacagtactt
     1021 attttactat gcaagagaac tcggtatagg aaaataaatt aagggggaga aattatggga
     1081 gtaataggaa caatatttct gttctattta attatatcat atctagctgg agccataatt
     1141 tctgtgatta tattacttga aaatagagac cctgcaaaaa caatgtcttg gctattgatg
     1201 tttattatat ttccaggtgt aggtttaatg atatatgcta tttcaggtag aaatattaga
     1261 aaaagaaaat tatttaagac tcaaaaacta gctaataata taaaagaaaa gaaactattt
     1321 gatacattag aaaagataac agaaatagtt gaattagaaa aagaatctat aaaacaaaat
     1381 aagcttttaa gagatgaaga ggatggtagt tatagaaaaa gggtaataaa tatgttgtta
     1441 aagactggta tgtttccctt tactaaaaat aataaagtgg atgtatttgt agatggaaat
     1501 gaaaagttta aaagacttat agaagatata agagaagcta aagaccatat tcatttagag
     1561 tactttatca tcaaagatag tgaaataggt agggtgttaa aagaagaact tataaaaaag
     1621 gctaaagaag gcattaagat aagaatttta tatgatgatg taggatgctg gagattttgg
     1681 tttaatagaa aatttttccg agaaatgagg gaagtaggta tagaaattgc agcattttta
     1741 cctacaaaat ttcctataat aggagggaaa ttaaactata gaaatcacag aaaaattgtt
     1801 gttattgatg gaataattgg atatacaggt ggaataaata taggagatga atatttaggc
     1861 aaaaatgata agtttggata ttggagagat actcatatta ggattaaggg tatttctgta
     1921 tacatgcttc aaatgacatt tctgattgat tggtattata cgacaaaaga agtattagtg
     1981 actaaaaatt atttcccaag tgtagggaat gttggtgaaa gtatgataca agttgttgcg
     2041 agtggtccag acagtgactg ggaagatatt cattatgctt atttttctgc aatatgtcag
     2101 gctagaaaaa atgtttatat agaaactcca tattttattc cagatgaaag tctactaaaa
     2161 gctataaaga gtgctgctct tagtggagtt gatgtgagaa taatatttcc taaaattgca
     2221 gaccacaaga tagtaaatat agcatcttat tcatattttg aagaaatatt aagagcaggt
     2281 ggtaaagttt atttatataa taaaggattt atacattcta aagtcgtaat aatagatgat
     2341 aaaattgctt ctgcaggtac agctaatatg gatttaagaa gttttatgct taactttgag
     2401 gtaaatgcat ttatctatga tgaagaagtt attagggtaa tgacagatga tttctttgag
     2461 gatttaagtc actgtgaaga acttaatttg gaggtattta agaatagaaa tatcatacaa
     2521 aaaatcaaag aatctgtagc aagattattt tcaccaatat tataaaaaat tattaaaaaa
     2581 ggtattgaaa attatgtgtg attggtatat tataataatt gttagcactc tattatatag
     2641 agtgataata aataaaaagt atatatataa atctacatat ataagtagta ttaatttaaa
     2701 aataactaaa aacataggcg aactagtcta tacttaatat tttaggaggc gtgaataatg
     2761 aaaataagac cattagctga cagagtagta attaaaaaag tagaagcaga agaaaaaact
     2821 gcaagtggaa tagttttacc aggagcagct aaagagcaac ctcaaatagc tgaagttgta
     2881 gaagttggac caggtggaat agttgaaggg aaagaaataa aaatggaatt gacagtagga
     2941 gataaggtta tattccaaaa atattctgga acagaagtta agatagaagg acaagaatac
     3001 acaatactaa gacagagtga tgtattagct gttattgaat aaatatagaa taaatttatt
     3061 aggaggggtt taaaatggct aaagaaatta aattttcaga ggaaacaaga agagctttag
     3121 aagctggtgt aaataaatta gcagatacag taaaagtaac attaggacct aaaggaagaa
     3181 atgttatatt agataaaaaa tttggttctc cacttataac taatgatgga gtaactatag
     3241 caaaagagat agaactagaa gatagatttg aaaatatggg tgctcaatta gttaaagaag
     3301 tagcaactaa aactaatgat gtagctggag atggtactac aactgctaca gttttagcac
     3361 aagctataat aagagaaggt ttaaagaatg taacagcagg ggctaaccca atacttttaa
     3421 gaaaaggaat acaaaaagca gtaacagtag cagtagaaga attaaaaaat caatcaagaa
     3481 tagtagaaac acaagaggct atatctcaag ttgcttctat atctgctggt gatgaagaag
     3541 ttggaaaatt aatagcagaa gctatggaaa tagtaggtaa agatggagtt ataactgttg
     3601 aagagtctca aactatgaat actgaattag atgctgttga aggtatgcag tttgatagag
     3661 gatttgtttc tgcatatatg gttacagatg tagataaaat ggaagcagtt ttaaatgacc
     3721 catatatatt aattactgat aaaaaaatat ctaacataca agaattatta ccagttcttg
     3781 aacaaatagt tcaacaaggt aaaaagttat tgataatagc tgaagatgta gaaggtgaag
     3841 cattatctac attagtagta aataaattaa gaggaacatt tgatgtagta gcagttaaag
     3901 ctccaggctt tggagataga agaaaagaaa tgcttcaaga tatagcaata cttacaggtg
     3961 ctcaagtaat atcagaagaa ttaggttatg atttaaaaga agctgattta tctatgctag
     4021 gtagagcttc atctgttaag gtaactaaag aaagtactac aatagtagat ggttctggag
     4081 ataaaaaagc tatagaagat agagtaactc aaattaaaca tcaagtagag caaactactt
     4141 cagattttga tagagagaaa ttaatggaaa gattagctaa acttgctgga ggagtagctg
     4201 ttgtaaaagt tggagctgct acagaagtag agttaaaaga aagaaagtta agaatagaag
     4261 atgctcttaa tgcaactaga gcagctgtag aagaaggaat agtagctggt ggaggaactg
     4321 cttttgttag tgttatacca gcaataggaa cactaattga gagtttagaa ggagaagtta
     4381 aactaggtgc tcaaatagtt aaaaaagcgt tagaagagcc attaagacaa atagctataa
     4441 atgctggtct tgaaggtgct gtaattgtgc aaaatgttgt taattctgaa gcagaaactg
     4501 gatttgacgc attgaatgaa aaatatgtaa atatgataga agctggtata gttgacccaa
     4561 ctaaagttag tagaagtgct ttacaaaatg ctgcatcaat agcaagtact ttcttaacta
     4621 ctgaagctgc tgttgctgac cttcctgaaa aagaagatgc aggaatgcca ggaatgggtg
     4681 gcggaatgcc tggtatgatg taatttaaaa aatttaaaat ataaatttta atataaagaa
     4741 ctatttcgac ttagatttta aactctaagt tgaaatagtt cttttgtata tatctaattt
     4801 ttgtacatct ataaattcaa tacacatatt tagataatca gtatctagtt tgtaataata
     4861 ttttagagta gtattgttat tttttaggtt atgattttag atatatatta attaaggtat
     4921 aattgttgat agagaataaa tcaaatttaa aaggatgcga taatatggac ttaagaaaat
     4981 tgcttgaaga agttaaaaat gaaaatattg atatagattt tgcgttagaa aagttaaaag
     5041 atttacctta tgaagacctt ggatatgcaa atatagatca tcatagagaa ctaagaaatg
     5101 ggtatccgga agttatttat tgtgaaggta agagtgatga gcatatttta gggattattg
     5161 ataaaatgaa tcaaaaaagt tctaacatat tgggaacaag gtgcagaaaa gaaacttttc
     5221 tgaaaattaa agaaatctat aatcatgctg agtacgaaga ggcgtctaaa attcttaaga
     5281 ttcaaaatca tgatatagag aatataggaa aaggtaaaat tgtgattgct acagggggaa
     5341 cttctgatat accagtagca gacgaagctt atcatacagc taagttttta ggtaatgatg
     5401 ttgatagaat atatgatgtt ggagtggcag gtatacatag gcttttaaat aaaagacata
     5461 aaatagatag tgctagagta atagtagccg ttgcaggtat ggaaggtgct cttgcaagtg
     5521 taattggtgg actggttgat gttccagtaa tagctgttcc aacctctgtt ggatatggag
     5581 caaattttgg aggattagca gcattactag ctatgttaaa tagctgtgca tctggaatat
     5641 ctgttgtaaa tattgataat ggatttggag caggatattt agcatcaatg ataaataaac
     5701 tgtaaataca ttgatataaa ttaaacaaaa ctatataata aaatttaatt tctattatat
     5761 ttttactatt aaaattgagg agacatatat gagtgaaaaa atactttatt ttgatataat
     5821 aagcggtata tcaggggata tgacccttgc aagtttatta aatttaggtg tgcctaagga
     5881 aatttttttg gaggaaattc ataaactaag aatgagcgat gaatttaata taaacatcag
     5941 ctcgaaaact gaaaatggaa tagtaggtac aaaagtagaa gtaattacaa aagaaaaaca
     6001 tacacataga aatttagtgg atatatttga ggttatagat aaaagcactc taaacgaaaa
     6061 tgtaaaatct aaagcaaaaa aaatatttat ggtaattgga gaagcagaag caaaagttca
     6121 tggaactaca atagacaaga tacattttca tgaggtaggg gctatagatt caattgtaga
     6181 tatagtagga gcttctatat tagttgactt actttgtgta gataaagttt gtgctagtac
     6241 agtgtctgtt ggttcaggat ttgtaaaatg tgaacatgga attataccta tacctgcacc
     6301 tgcaactata gaaattttaa aaggtgtgcc aattaaatta aataatgtaa atggagaatg
     6361 tacaactcca acaggagctg caatcataaa agtcttgtgt gatgagtttg tagatgagct
     6421 tgaattttct ccaaagcaaa ttggatatgg tataggtcat aagaagtttg aagtaccaaa
     6481 tatactcaga actgtattag gtgaaaaaaa aaagaagaat taatttatga aattagtgca
     6541 aacattgatg atatgtcttc agaaatctat tcttatttgt atgaaaaaat attagatgag
     6601 aaagcattag atatttatac agagagcatt tatatgaaga agaatagacc agcaacaaaa
     6661 gtatcaattt tatgtaatga atcagattta gaaaaattta ttaaaatatt acttttagaa
     6721 actagtactt ttggagtgag atataatgca tataatagag aaattctaga gagaaaattt
     6781 gtaaaattag atacaaaata tggagtggtt acagtaaaac tagggtatta taaaggaaaa
     6841 ctagtcaagg ctactccaga atataatgaa tgtaaaacta tagcaaaaaa tgaagatatt
     6901 cccataaaaa aagtgtttgc tgatataaat tttagaataa aagaagaatt tagtgaaaac
     6961 ttattgacat aagtaataaa ttttgataaa ttaatattca gccttattaa ataaaagtaa
     7021 acagaaaaaa atatataaaa tataaactca ctcgtatatg ctcagaaata tggtctgaga
     7081 gtctctacca agataccgta aatatcttga ctatgagtga aattattata ccaaaagacc
     7141 tagttaagta aatgtgtagg ctgagttaaa ctccctatgt gttggctata agataaaggt
     7201 attttggaag cctgtatagt aatttcactt ttgctagaaa ttatggaagt tactatacag
     7261 gttttttgtg taaaaagatt taatataatt tagactgtat tgtgttaaaa taaatatata
     7321 aaaactatat tatacaagga gagatgtaaa tttatgaaac atgaattagt acttgtaata
     7381 gattttggag gacaatataa tcagttgata gctagaagag ttagagaaaa caacgtatat
     7441 tgtgaaatac ttccatgtac tgcaagcata gaaagaataa aagaaaaaaa tcctaaaggg
     7501 ataatattta caggcggtcc aaatagtgcg tatttagaag attctccaac aatatcaaaa
     7561 gaaatatttg aactaggagt accaatactt ggaatatgct atggtattca aataatgtct
     7621 catgtattgg gtggagttgt aagaaaaggt aataaacaag aaaaagaata tggaaaaaca
     7681 gctataactt atggaaaatc atcattattt gaaggaataa ctacaaatag tgtatggatg
     7741 agtcatacag atttaataga aaaagttcca gaaggattta ctatagttgc aaatactaat
     7801 gattgtccag tagcagctat ggaaaatgta gaacgaaacc tatatggagt tcaattccat
     7861 ccagaggtag aacactgttt ggaaggggac aagatactta caaacttctt atataatatt
     7921 tgtaaagtaa aaggtgactg gactacagat tcattcatag aagataaaat aaaagaatta
     7981 aaagaaaaaa taggtgataa aaaagcttta tgtgctttaa gtggaggagt tgattcttct
     8041 gttgctgcag ttcttattca taaagcaatt ggggacaact taacttgtat atttgttgac
     8101 catggtttac ttagaaaaaa tgaaggaaat gatgtagaaa gaatatttag agagaaattt
     8161 gatataaatt taataagagt taatgcagaa gatagattct tatctaaatt aaaaggagtt
     8221 tctgaaccag aagctaagag aaaaataata ggtgaagaat ttataagagt atttgaagaa
     8281 gaatcaaata aattaggaaa aatggatttc ttagtacaag gaacaatcta tccagatgtt
     8341 atagaaagtg gacatggaaa tgctgctact ataaagtctc atcataatgt tggtggaatc
     8401 ccagaagatg tagacttcca agaaattgta gaaccattaa gagagttatt taaggatgaa
     8461 gttagaaaaa taggattaga gcttggtata gaagaaggat taatatttag acatcctttc
     8521 ccaggaccag gtctaggaat aagagttata ggtgatgtaa ctaaagaaaa atgtgatata
     8581 ttaagagaag cggatgctgt ttatatggac gagcttagaa aagcaggttt atacagagaa
     8641 atatggcaag cttttgcaac attaccagat gttaagactg ttggagttat gggtgatgaa
     8701 agaacatatg cttatttagt tggtttaaga gcagttactt cttctgatgg aatgacttct
     8761 gactggtata agatgcctta tgatgtatta gaaagaattt ctaatagaat aataaatgaa
     8821 gttgatggag taaatagagt agtttatgat ataacttcta aacctcctgg aactattgaa
     8881 tgggaataaa atatagaatg ccaaaaatcc acataaatac aggatttgag gtctctctta
     8941 cttctatgtt atactggttt gatactatca atatttgcca gtatcttatg gattaataag
     9001 caaaaaacat cctgctgaat gataaattca gcggggtgtt tttattttgt tttagaactc
     9061 ctttgctctg aaactcgaag tatttaacac tgatgatgtt gttatctttt agttcctttt
     9121 gtgtcatgct ctgaaagaca aattgataca ataaaaaagt aatttcttaa tcattgatgg
     9181 agatatgtat ttatgttact cttgatggta atttgagtaa tattgttcat agctttttat
     9241 attcacttaa ttagaaaacc atttggtata atcataaata aacttgatga tataatagaa
     9301 aagatttata attattagaa gtatataaaa gtattttatg tctatgaaat gtatgtctat
     9361 aaaacatata gatgactttt gtatattaat gtatgaatat tgatattata gaagaattga
     9421 gttgtcaatg atactaaatc aaatatttat agaagctgga gggattatga gaaataaaat
     9481 aattatagga attacttttt cacttgtatt actaatgtct ggatgtgctt caaaacaaac
     9541 agcagaaata aacgtattag caactactga tttacatgga gttatacctt atgagttaac
     9601 ttcttatgta aaagaagaaa gaaaaaaaga taaaaatcta actttagtag atgcaggaga
     9661 tttttttgat agtggcgaag tatctggttc tagcatggat agttatttta gtgctaggta
     9721 taaggatatt gataataaca ctgagcgtta cattgagaca cctatttcaa aagatatgaa
     9781 agaggtaggt tatgatgttg cagttcttgg gaatcatgaa tttatatcca acaataaatt
     9841 ttatctagat aatatgatat ctgattttga gaaacaaaaa ataaatattt tatcggcaaa
     9901 tacgtataaa aaaaatggag atagttatac aaaaccatac ataataaaaa atattaatac
     9961 acctgaagga aacgtaaaac taggaatttt agggcttact ataaaagaag ttggtgagag
    10021 gaaacagtgg aaagatggaa aacttgttga ctctaagtct ttagaactaa aagaccaaga
    10081 gggttacaat ggtgaattgt atatgaatga tttagtagaa gatgctaaaa agtgggttgg
    10141 tataatggaa aaagagaagc ctgacattat agttgctgtg gcacatacag gtgagaaacc
    10201 taagaaacct aaaaacccag gaaatagaat acaagactta gctcaacaag ttgatggaat
    10261 tgatgctata gttgcaggtc ataatcatgt tcaaattgag caacatgatt ataaaaataa
    10321 atcaggagaa aatgttatag ttactgagcc aggaaagcat ggggaatgta tttctaagat
    10381 taattttaaa ttagaaaaaa acaatgataa atggaatata gttgacaaat ctagtaaatt
    10441 aattaaattt gaaaaaaatc aagaaagtga taaatttgga gaatttattt cttcaattaa
    10501 taaagtaggt aaagataaga aagaaataag attatcagaa gtaaagactc ctgaatggga
    10561 taaaatatat gtttttaaat ctggaacatc tgcagatgat atatataaaa cgataggata
    10621 taaatggaga aatatatcat ctccaaaggg tgatgacatg gtgcagattg ttgtaatgaa
    10681 taataataag cctgttagct atgtatatgg tgaagctgaa gttatgccaa ttaatataaa
    10741 atgtgatgaa tcagagtata aagataatgt tgtaactatt tatcctaata aaaatgataa
    10801 atttaaaatt gaaaaaggta aacaagaata tagtattaat ttaaaacata tacaatagaa
    10861 acttttatct tatttaagtt tagattgtac ttaaaataaa gtgtgtatta ttttaaaaat
    10921 tgatgataat taaaatcaca acattaagga atagtacaca ctttttatgc taaaaaatag
    10981 aatgttaaaa aattaaacct ttaaattaaa gtacattgct tatattatcc aatattatct
    11041 tcaaaggttg tgtaatattt ttatccttat gtaatattgc taacatttta ttttccatat
    11101 ctatcccatc taatttaatc aatcgcaatt ttttatgaaa aagtgaatct aataataaat
    11161 tttctggcaa aatggttata cctaaccctg cttctgcagc tttaataagt gcaaaagaat
    11221 taacactttc ccaaacagga taagcttttt ggtttgaaag agataataca ctgtccaaag
    11281 tatcgcgaat ggcacttcct tgctcacgta acaataacgg aaacgtgcat aactgtcgta
    11341 gagataaggc ttgtttagat aaaggaaaag ttggagcaca tgcaacacat aacttatagg
    11401 aacctaataa aattgtacgg aatgccccct gtggttctat accttcccaa aaacatatat
    11461 cagcttctcc actttttaaa atatccatag ctgaattagc actttcgaca cgtacattca
    11521 ctttaagaga tgggaatgaa ttttttagtc gacttaaaat tggtggaagt aaaaaagagg
    11581 caattgtaat gctagaaaca atgtttatag gtgtacattc ttctaaacga ctgattcttt
    11641 tgtctaaatt acgacaagca gttaagatac tacgtgcttc ttctaaaaga gaaatgccac
    11701 agcgagtaag acatacccct cgtggtagtc tgtcaaataa tgctgtttca gcttgttgtt
    11761 caagttcagc tatagcatga gatacagcag attgtgtgat atgtaatttt tttgcagcac
    11821 ctgtaaaagt gcctgtttgt tcaattgctt ctaaaatctc caaatatcgt atgtttatca
    11881 taataaatat cctcactaga catgaataaa attgattaat tccattaaat tctatcattt
    11941 tacagattac aaagcaacag gtatactgaa taatatgaag tgaaaagaag gaggaatatt
    12001 ttgaatcaaa gcagaaaaac atatttttgg cttttaatta ttaacttgtt tattagcaca
    12061 ttcacttttg gtggagggta tgtagttgta cctatgatta gacgttattt tgtaaatcaa
    12121 aagcaattct ttacagaaga tgatttgatg agcatggcag cagttgcaca atcaactcct
    12181 ggagctattg caattaattt atctgctttg gcaggttatc gagtagctgg tactttaggg
    12241 gttgtcatta gttgtatagc agctataata cctccactcg ttattcttgg attagtatca
    12301 gcattttaca ccacttttat atctaatgcc attgtaactg cagtattaaa aggaatgcaa
    12361 gctggtgttg ctgcactaat tgtggatttg attattgaca tgtgctctat gatattaaaa
    12421 caacgttctc tatttttatc agctatgata cctattgctt tctttgcaaa ctttgtgatg
    12481 agtataaatg taatttttat attatctgtt tgctgttttg tatgtgtaat gcaagctttc
    12541 tacaagaaga gggaaaataa atgaatacaa tttggaactt attttttata tttttaaaaa
    12601 taggattgtt tagtattggc ggtggttatg caatcatacc tttaatccaa gagaaagtag
    12661 taaatcaaac tggatggata agtgagaaaa tgtttacaga tattataact atttcacaaa
    12721 tgacaccagg gccactggct gttaatactt ctacttttgt tggacttcaa attggagggt
    12781 tttggggagc agttgcagcc actttaggtt gtgtattatg tggtgtagta atatctctat
    12841 ttttatataa tttttttcaa aagcatcaga actctactta tatatttgaa atattaaatg
    12901 gtctaaaatc agcttcatta ggtttaatta tctcagctgc ggctacaatt ataatccttg
    12961 cattatttgg gacgaataaa gtgtacttca attctatatt tgagatgcta aactggactg
    13021 cactaataat cttttttgtt acactactga tagtacgtaa gtggaaaatt aatcctattg
    13081 tgattataat aataagtggt atactgggaa tattttttta tttataagtt tttggtaagt
    13141 agaggatatc tattttttta tatcttaaat ccaaatagcc aataaagtaa ggctatttgg
    13201 atttttaata aattctgaaa agataatcag aaacccatat aacatttaaa ttatatcact
    13261 ggttttctac aaaccaatca taagcttctt ggcaaaattt ctcactatct atatagtaac
    13321 tattatgaac attattaatt tcaacaagtt tctttttaca ttttagtgaa ttataatagc
    13381 tatcaaaata ttgggtttta aaatatctat catgaagtgt tttaaagaca agagtaggta
    13441 tgttgactcc atcttttatc ttactatctt ctgcaataaa gcattctaac attgtattaa
    13501 ttatctttgt actatttttc caaatatgag gatttttctt ttcaaatatt ttataaaatt
    13561 cattatcata gacttcatta taacctttat acttaggtgg ttttactgtt atgtgaaaat
    13621 taggaagaaa cttaaagaaa aaatataata atttttatgt tctgttttat atattattca
    13681 tattttatca cagataatat actaaagtta atttttttat tgtacaacta ttataataat
    13741 tcttctataa tgtaagacat tctataattt tatatttaag ttcatgtgta tttaattgtt
    13801 tttatataaa atgtccagta atactatttg gatttatttt tatttcatca ggagttccag
    13861 aagcaacaat ttcccctcca tttattccac tgtctggacc tatatcgata atccaatcag
    13921 aagcacgtat aacctctgta ttgtgttcaa taattaaaag tgaatgctgt tcatttacaa
    13981 gttttctaaa agtaattaac aaattttcta tatctttaaa atgaagtcca gtagtaggct
    14041 catccaatat gtacagcatt cgttttttag tttttgtccc taattctttt gctaatttta
    14101 tcctttgaga ttctcctcca cttaatccta atgtattttg tccaagcttt agatatccaa
    14161 gtcccacttc atctaataag gagagttttc tatatatatc agagcaatcg ctaaaaaatg
    14221 tttttgcttc tgctacttcc atgtcaagta tatctgcaat tgtctttccc ttgtattgta
    14281 tagacagtat ttctttttga tatctcttac cttgacattc actacaagtt acccattggt
    14341 ctgccatata ttgcagaata atttttgttt tacctaatcc ttgacagttt gggcattgcc
    14401 cctttttgct attaaagcta aaatagcttt catccaataa tttttgtttt gcttgtggag
    14461 ttttagcaaa tagagaacga atttcatcaa aaatattgat atatgtagca ggtgtagaac
    14521 ggctagattt tccaataggt gtttggtcca ttaagataaa atcatcaata gcatcaaatc
    14581 cagtaaattc agtataattt ttatctggga tagatttttg tttcaatttt tcttctagag
    14641 caggaagtaa actgtgaaat acaagagagc tcttaccaga accactaaca cctgtaatag
    14701 agcacataca gtttaaggga atttctacat caatattttt taagttattt gcatggcatc
    14761 cttttaagct taaccattta cttggtataa ttttattttg tgaacttatt ttattgtatg
    14821 tgcttaaata tttacctgtt atagagtttg gattttttat aatttcttgg gttgtacctt
    14881 ctgcaataat gaacccccct tttgtaccag cacttgggcc tacatcaata atataatcag
    14941 cagacagtat tgtatcttta tcgtgttcca caactataac agtattaccc ttatctctta
    15001 tctcttctat cattttgatg attaaattat ggtctcttgg gtgtaaacca atagatggtt
    15061 catctaaaat gtaggttaag cctactaatt cacttcctag ctgacttgat aatcgtactc
    15121 tctgcagttc tcctccagat aaagttggag ctgttctatc tgttgatata tagctaagac
    15181 ctacctttaa tagataacta actcgaattt ttaattctgt taagatatca tttaccaaag
    15241 agagctcatt tttttgaagt tgatttggta attcacacaa ccaattccat aactgttcta
    15301 tcgtcatttt tgttagttca gggaagcgat aacctttgat tgtagtgaat ctagcctcaa
    15361 tgcacagcaa ttcgccacca catgtattgc aaggaatttt gttcatatat tgatgcaagg
    15421 tattattttc aaaactagat tctctaaaaa gtctttgaat gtggttgatt gctcctgaag
    15481 caggtcttct aatctttgat tctcgtccct ttgattcaaa gctaaattca tatatcttat
    15541 cgtctgtacc atataagatt gcatctataa aatctcttgg taattcattc caaggtatat
    15601 ctaggtctat atttttatct tttgctattg catataattc acctaccatc caattaccat
    15661 ttggcttttt ccccctcaat tttccaaaat agtaagtagc tccatctaat attgaaatag
    15721 ttgggtcttt tacaattaat tgaggattaa cttgataggt aaaacctaat ccattacaat
    15781 cgtgacaagc tccagtatgg gagttagcat tgaaggttga agtatttatc ttagaaaaaa
    15841 tagtttgaca atgtggacaa taattttttg tattattctt tttttctaat ggaattttgc
    15901 aatatggaca gtaacttttt ccgattgata caaataacat tcttaaataa tcccaaatgc
    15961 ttgtaagagt accaacagta gagcgaggat tttggcttcc ttttttctgt tcgatagtta
    16021 tagtaggggt taatccctga agtaaatcaa attccggttt ttgaagctgt tctgaaagtt
    16081 ttgctccatt acttagattt tcaaaataac gtctttttcc ttcttcataa atcgtatcga
    16141 aagctaaaga agattttcca ctaccactta cacctgtaat aacagttatt tgattttttg
    16201 gaattgtaac ctcaacatcc tttaaattgt tttgccttcc tccttttaaa tagatagagc
    16261 ttttattatg acaaagtgaa tttttaattg atttatttat tgattttgta aatttgaatt
    16321 tcttttctag ttcaagagga ttgcctaatt cttttatttc cgaaatacct aatattttta
    16381 actgagaaaa gattgatttc aaataatctt caggcaattt ttctattaac aaattaaggt
    16441 cttctatttt tatatttccg cttgataata tctctgccat ttcatctaat aaattttttt
    16501 ctgctcttgt taattgattg tattttttgg aacttaattc tgtccataaa tcccatggaa
    16561 gcaattctaa accaatcata ttattaaagt catgtagaag attacccttt acagaatgcc
    16621 aacctttcca atttttatta tatccaaagt catctggatg agcatgtcct tgccgacatc
    16681 ttatccaggc ttctgaacca gttaaaaaac catctgtttt tccgacatca tgagtgtcaa
    16741 aattaatttg aaaataattt ttttgtatgt catctatttg tgcatctatt cttatccatc
    16801 tctttgttag agtatcatag tattctacaa gccagtggtc ttcataagta agctcacttt
    16861 caaaataatt agcaaaacct gctctcattc tagcctcaaa acctcgatat cttaggagcg
    16921 atacaagaag taaagaataa tctctgcaca ttccaacaag cctttgtttt gggtttcttg
    16981 gaatagttag tgggttagaa tttatttcaa atattctttt taacatttga ggaattgtac
    17041 gaagcaattc ctcatcagat tgttgtttat taaaggatat accatataat tttccttggt
    17101 ctccatgaat tactaggctt tgaaccactt ttaataattc aattggagtc tttggtaaat
    17161 cttgatattt attttcaaat tttttaggat ttgtgatgat gctttgattt ttatagttat
    17221 ttattttcat ttatatttca cctctctaaa tggatgatat accctgacat ggtgtcatat
    17281 gcaaggacaa tttagatttt ttggccaaaa tttaaaaata aataaaaaat gatacagtga
    17341 taaattgtaa tacaaatata gtttcaaatt gcatataata taattattta ataaaaccat
    17401 tatctatgga atgttaatga aatgttaaga tagcattctt gaatattaag aaatagaata
    17461 ctataatata gtgtgaagga ttcttagtaa aaaaatttgt aagtgttaat atacattaaa
    17521 aaataggttt ataatttgga ggaaaaaaat gaaattatca aggtataaga aaaatagttt
    17581 agttctgtct ataattttat gttcacttat tatttcaatc cttgtaatta ctgtttttaa
    17641 taccgtaaaa ctacacaata tatctaataa acaatctaaa aactatttaa acgatgtatc
    17701 tacacagatt gtaatgaatg ttgattctaa aatcaaattt attttatccg acttaagaat
    17761 aatggcagat tttattaagc aatatgaagg tgatagtcga tatgagtatt tatctaaaag
    17821 aaagactagt tataagtatt atgatgttgg aataatagat ttaaaaggta aagctgagtt
    17881 tttaagtgga aaaaagtttg acttaaagaa tactgcttcc tataaaaaag gaattgaagg
    17941 taaagaatac tcagaagtaa tagagtcaat gggttttgtt ctttatagtg tacctatatt
    18001 taatgataat catgaagtat ctagtatttt aataggtgta tctgataaag aaagtatgaa
    18061 tgagattctt aatatagata actttaatgg agaaggaact attgaaatta ttaatagtaa
    18121 gggaaaactt cttttcatag gaaaaaatac tgagttaata aaagacctta gccataaata
    18181 taaggattct gcagatgaac cttgggcaca aaagatgctt aatgatttta aaaatgataa
    18241 atcagggaat attacaataa cctcatcaaa aggtgtacaa tgcttattga cttatcatcc
    18301 aattacaaga ggtttaaatg attggcattt tcttctcata gtacctgaag atgctgtact
    18361 tggtgaactt aataagttaa attcttttac aataacaatg acatttataa ttacatgtat
    18421 tattggaatt ataacattaa ttttatatat tataagaaga aaatatgtaa atcaaataga
    18481 aaatattgca tatttagata gtataacaaa tggcataaat tcaactaagt ttagtatgct
    18541 agtcaaacct ttaatttcag aatcacctga tagtacttat atgatgatag caatgaatat
    18601 aaaagatttt aagctaataa atgattgttt cggtagtgaa aagggaaata tgacactaaa
    18661 acatctttac aatattttgt ataaaaacat tgatgaaaat gaagaatttg tgtgccgtca
    18721 tgatgcagac cttttctatt tgcttattaa gaatagacca gtgttagaag ccctggagtt
    18781 attatataaa atagaagctg acacaaatta ttttaataaa aatagggaaa atccatactt
    18841 tttaagacta tcagtaggta tttacacaat tgaaaatcat aatgaagatt taattacaat
    18901 acaagaccat gcaaatacag caagaaaaag ctttaataaa actcatcaaa gtgatttttc
    18961 tttttatagt gatatagaaa gaaaacgatt aatatctgaa aaggaaattt caaatttaat
    19021 ggaaaaagcc cttgaaaata aagaattttt tatgtgctta caacctaaaa ttgatataaa
    19081 aagtggaaaa attagtggag cagagtctct tgtgcgttgg aaaaattcag aaaaaggcat
    19141 aatttatcca agtgatttta ttcctctttt cgaaaaaagt ggatttatat gtaagttaga
    19201 tttatatata ctagaagaaa catgcaaatt gatttctaag tggataaaag aaggtaaaga
    19261 agtgttgaga atttctgtta atgtatcacg tcaacatctg aatgataaat tgtttttaga
    19321 aaaatataag catatatgca ataaatacaa tgtaccaaca tgtctgatag atttagaact
    19381 taccgaatct attttcttag aaaatccaga agctatagat ataatagagg atattcattc
    19441 taatggattt aaatgttcta tagacgattt tggatttggg tactcatcat taggaatatt
    19501 aaaggatttt aaagttgata taattaagtt agaccgttca ttctttgtta gcaaaaataa
    19561 tatagaccgt ggtaaggtag ttattaagtc tattattgaa cttagcaaaa ggctaggtat
    19621 gaaagtaaca gctgaaggaa ttgaagaatt agaacaagtt gagtttctaa aaaatgtggg
    19681 atgtgattat attcaaggtt atgttttttc aaaaccatta ttaatttctg actttgaaaa
    19741 ttttgcatat gaaaataata aaattaaaaa tatccattat taaatgtaca agataaaaaa
    19801 tttaggcaag ttatataatt aaaaatataa cttgcctttt ttatttatat atttaataaa
    19861 aatatatttg cagattttgt aaaaataatt ttcaaatgtt gtaagttgtg gctaaagctt
    19921 tattgtatta ttctgaatat agaaagatag ttactgtctt agataaaaac tgaaacatac
    19981 ataataatat aaaatttgct atattaataa ctctaattat tttggaagga gggaaaatat
    20041 gataagtggg agaatgttac tcatcatgaa ttttctaaaa ggaaaaaata agacaagtta
    20101 caaggatatt agcaaacaac ttagtataga agaaagaaaa gttagatatg atataaataa
    20161 tttaaatatt gttttgcgtt cattaaacaa gtcagtaata caaaagatga ataaaggtgt
    20221 gttaattatt cctgatgact tccaagtagt atgtataaat aataacgaat atgtattttc
    20281 cttaactgag cgagtatcta ttatgaaaat tatatcaatg tttaaaatag ataatctaaa
    20341 cttagaaaaa ttaagtaaag aatttcaggt ttctagaagt tcaattaaaa atgaccttaa
    20401 tgttttgtca agtgaattag aaagaaacca aataactatt acttatgata aatcttttaa
    20461 aataagtgga gaagaagaca ttatatataa gcaaagattg aacatattaa aatcgtattc
    20521 ttatcttttt ggtaaggaaa aatctgattt aagtgtattt gagaagtatt tagtgaatgt
    20581 aattgaaaaa atattcaaag ggatttattt gattgatata tataattggt ctatgaattt
    20641 attattgcaa atgggatgga ctttaaatga tgaatctttt acatggtatg tgtcaaacat
    20701 tttccttttt acatggtata tacattcaga tgaaaaacat cctttagaat ctgcttcatt
    20761 aagtgagccg tgttttgaaa ataagtttga ccaagaattt gaaacaatta ttcaaaaaaa
    20821 gttgactaag gaacaaattt ttctgttaaa gagttttgta ttttttacaa ataaatatgc
    20881 aagtttaaac gaggatatgg atttgattag tacagaaatt atagttcaag acctaattta
    20941 caatatgtca gaaatattag agattagctt taaagaagat atgattcttt ataaaggatt
    21001 actcaatcat attgccccat tgatagagag aatcaagcag aatatacaga tttatgagga
    21061 attacttcat gtaataccag ataaatatca atatgtactt gaagctacta aggtttctat
    21121 tcaaaaaaac agagttttaa gtcaaataaa gaatgaaaat gaaacaatac ttttggcaat
    21181 acatttctta ggaagtatac atagaaatga gaggaataac tacaaaaata tattgttagt
    21241 ttgtggattt ggatatggtg taattgctat gttaaaggat agtttagtaa atgattacca
    21301 gataaatata gtagagagta ttccatcata taagttacaa gattataaag actgggaaag
    21361 tattgacttc attataacaa catcaaagat agtaatagac ttgcctaaaa caattattga
    21421 gataaatcca tttttacaag aagaggatta tttgaagttt gaagaaaaag ggataaaaag
    21481 aaagaacgtc ttaactaatt atatgtcaat aaaaaaaagg ttggactttt tagaagaaga
    21541 tgaccaaaaa agagtattaa gtattatatg tcaagaactt ggatacagtg atgagagaat
    21601 attatttaga caacttaatt taagtgattt aatagggatt gataccataa ggataattga
    21661 tggagatatg aaatgggaag atgctgtaaa atttagttca aacatacttg ctaattgtga
    21721 ttttgtatca gcacaatatg ctgagaatat tatagatatt ttaaaaaatg tgggttttta
    21781 tgctgtaaaa gataacgaat ttgctttact acatggcaat gatagttcat tagtcaaagt
    21841 aagttcgata agtttattaa tatgtaaaga agcagttagt tttggagata aaaaggttaa
    21901 aatcatattt tgcctagcaa gcagagataa aaaagagcaa attcctgcaa taattaatct
    21961 aactaaaatg gtttataaga ctaattttat tgctatgtta gaaagtgcaa agacaaaaga
    22021 agaagcagaa gttttaattc ataaatatga gaaggaggtc actgtatgaa taaattagtt
    22081 aatgtaaaat gttcatttaa aatacatgtt aattcaaaag aagaagccat tatatcgtta
    22141 gttgatgtag tgtcaaaaga aggatattta atagataaaa atcaattttt aaaagatgtt
    22201 ttaaagagag aagaaacatt gtcgacttat attggacatg gtataggtct tcctcatagt
    22261 caaagtgtag gtgttaaaaa ctcttgtatt acaataggaa agcttgatac tcctattgaa
    22321 tggacagaag aaggagaaaa agtggattta atatttttga tatcagtaac aaaagacaat
    22381 gaaaataatc ttcatttaaa gattttatca aaattagcac gtttattgat gcatgaaagt
    22441 tttagaaatc aaattagatg ttcagatgaa caaactgttt ataatcttat aaaagaaaaa
    22501 atagaggagg aagattaaaa tgagaatttt aaagtttttg caaaaacatc ttatgacagc
    22561 aacatcttat atgattccat ttgtggttgc aggaggaata ttatttgctt tatcagtaac
    22621 tttaagtgga caagctgctg ttcctgaaac aggctggttg gctaaactga atcaaattgg
    22681 agctgctggc ttggctttat tcattcctat attaggtgga tatatagcat ttagtatggc
    22741 agataaacca ggattagctc caggtatgat aggtgcatat ttagcaaaag aagtaaatgc
    22801 aggttttata ggtggtatca tagcaggatt tatagcagga tttgttgttt tacaattaaa
    22861 gaaaattaaa ttagctccta caatgagaac tttaggttct atatttattt atcctttgat
    22921 tggtacattg attacaggtg gtataattgt atttttaatt ggagaaccta tagcttcttt
    22981 tatgacatgg atgacaaact ggttaaatgg aatgtctggt gtttctaaaa ttcctttagg
    23041 tggaatctta ggaggaatga tagcctcaga tatgggtggt cctataaata aggttgctgc
    23101 tacttttgcc caaactcaag ttgacacact tccatattta atgggtggag ttggcgttgc
    23161 aatttgtata cctccaattg gtttaggatt agctacatta ttgtttccaa aaaaatttag
    23221 caaggaagaa agagattcag gtaaagcttc actattaatg ggatgtgttg gaattacaga
    23281 aggagctatt ccatttgcaa catcagatcc agttagagta ataccttgta ttatggctgg
    23341 gtcgattata ggaaatatta tggctttttt attaggatgt ttaaatcatg caccctgggg
    23401 aggcctgata gtattacctg tagttgacaa taggttgggg tatattgcat cagtattaac
    23461 tggagcagta gttgttgcag tattaatgaa attagtaaaa aaagacgtga aagaagatga
    23521 agaaattgaa gaagatttag atgaatcaat tgaattaata tttgaagaat tataaatata
    23581 aatggaagga atttgtataa aaaagtaaat ataaaactat aaatttaaag gagataagaa
    23641 tatgaaaatt gtagcagtaa catcttgtcc tagtggagta gcacatactt acatgtcggc
    23701 tgaatcactt gaattatcag ccaaaaaatt tggtatagaa ataaaggttg agactcaagg
    23761 aagctctgga atagataatg aattgtcact taaagatatt gatgaagcaa cttgtgtaat
    23821 attgactaat gatgttgaga ttagaaatat ggaacgtttt aagggaaaga aggtagtaag
    23881 aatgagtgta tctgagataa ttaaaaaatc tgatgcatta attaagaaaa taaaagatac
    23941 ttttcaataa aaattgattt attttacata taactcaaag atgtttttaa agaaattttt
    24001 attaaaagca tctttgaaaa tatcttaaaa atagaataaa aggagatata gtcatgaaaa
    24061 agttaccaat aaagactgtc gtacaaagat tactaaactt acaagaagag gggaaaagtg
    24121 caactctttt aggaattggt cctatgtcac caaacttgtt acaagcaagt tttgaactag
    24181 caaaagatga tgattttcct ttaatgttta tcgcaagtag aaatcaagta gatgcagatg
    24241 aactaggtgg cggttatgta aatggttgga atcaggaaac ttttacaaaa gatattaaga
    24301 aggttgccga caaagttgga tttgatggtt tatattattt atgtagagac catggtgggc
    24361 catggcaaag agataaagag agaaatgacc atttgcctgt tgatgaagca atggagttag
    24421 gaaaaaaatc ttatttagcg gacattgaag caggttttga cctattgatg attgacccta
    24481 caaaagaccc atttgaaatt ggaaaagtaa ttccactaga tgtagtacta gaaagaactg
    24541 tagaattaat tgagtattgt gaaaacgaga gaaaaagact taatctacca gacataggtt
    24601 atgaggttgg tacagaggaa accaatggag gtctgacttc aactgagacg tatgaaacat
    24661 ttataactag actaaaggtt gaactcgata atagaggttt gccaatgcca acatttatag
    24721 ttggtcaaac tggtacttta actagaaaga cagaacaagt aggaactttt aattttagaa
    24781 atgcttatga tttagctcaa atggctaaga aatatggagt tggtttaaaa gagcataatg
    24841 gcgattactt agatgatgta actttattag aacatatacc atctcaaatt attgctacaa
    24901 atgtagctcc tcaatatggt actgaagaaa ctagggcata tttaaaatta gcagaagttg
    24961 agtgtaaatt agaaaaagag ggcttagttg agaaaacttc taatatcaga catgttcttc
    25021 ttgttaatgc aattgaatgt ggacgttgga gaaaatgggt agtaggagaa caaaaaaatc
    25081 taactactga agagatattt aaggatgaag ttttatctaa tgaaatacta gatattgcag
    25141 gacattatac atttaataat gatgatgtta aaaaagaaat agaagtgctt tatgataatt
    25201 taagtaagaa taatattgat ggtcaaagat ttgttgtaga ccatattaaa cgtcctttgc
    25261 gtgattatgc agaatgctat aacttaaaag gtgttactac gaggatttta aataaataat
    25321 aggacttata gtggtgagta ttgttatact aggtatttgt agttataatt atacttacca
    25381 ctattaaatt taggaggact aatattttga ttaatttaat ttttgatgta gatgatactt
    25441 tatataatca attaacgcct ttttacactg catataataa agtgttttct tcaataaagg
    25501 atatttctat tgaagattta tatatgagta gtagaaagta tagtgatgag gtatttcata
    25561 tgactgaaaa tggagaaatg ccaatcaaag aaatgcatat ttataggata atgaaagctt
    25621 ttgaggagtt gggaaattct attacagaaa aagatgcaca aagttttcaa gatgagtata
    25681 tatatcaaca atcacaaatt acactaatac cagaagttga gaggatttta aatttttcta
    25741 aagaaagaaa tattaatcta ggaattataa ctaatggccc atcaaaccat caaagaatga
    25801 agttaaagca gttaaatatt gaaaactggg ttgataaaag taatattttt atttctagtg
    25861 aggttggatt ttctaagcca gatactaata tttttagagt agctgagaat gttatgaatt
    25921 tagatagaga aaatacatat tatgtgggtg attcttatag aaatgatgta ttaggtgcta
    25981 aaaaagctgg ttggaagagt atatggttga accatagagg acatgaggta gaagagttgt
    26041 tttataaacc tgattttgta attttggaac ataaggattt gatatcttta tttataaaaa
    26101 tatgtagtta taaaaatatg tagtaaaaaa atgttaataa tagaattgta taaaataatt
    26161 aataataact atataaaatt atatgcttag attgtgagca atctatttta tgttaaaaat
    26221 agattattta gaagaagggg aaatcttaaa aaaatttgaa tatccccttt ttattattta
    26281 attaaaatga aatagttaga aatatatttt atttagttta gtcaataaca ttttgggatt
    26341 ctttataact acatgttaac tggtgaatag gtttatcata tggtttaacc catcctttat
    26401 taatacttaa ttctgtaagt gctgtgtgac cttctaccat ttgagttaat gaagctgaat
    26461 atatagctct taattcaggt gtactacttg tcaatgcaga attaagatac atattggcag
    26521 atgctttagc agatgaaagc atacttaaca ttattacttt atcgtctata taagtattgt
    26581 tcttaattag attttctatc atatttctca tgttatctat acctcctcag aaattagtat
    26641 ttcattttca actataaatt gttgtatagc tttaattctt ccttctgttg ctaatatact
    26701 agattctgat tgtcttttta ggtcttcatc tgatattaac atatttattg ctctttgcat
    26761 aagtaatccg tcagactcca tttttataac tgctgctaaa gatatttttt cagtttctga
    26821 aagtattctc atttaatcat ctcctatatt gtaatttatg ctttaatagt atgtctttct
    26881 tttcaaggaa ataaccatta cactttttta cagtatttta tattctcttt atatcaaagc
    26941 ttagtcgact taatatatta atataatttt gtaggatatt tatcattaaa tatctataaa
    27001 ataaattatt tgaatattca taaagcaaaa tttatttgta tgtacttctt caagagtcaa
    27061 tatgagtttt ttcaaaaaat taatttttat gataatcatt aagggctata tttttcttaa
    27121 agttgtgatt atcattatta atttactaaa atactttaat gaaaaatagc taactttaat
    27181 tgtaggatat tcttaatata tttgaaataa ataaaaatat tgaaggatat aatattcaat
    27241 tgatatataa ataataaatg atagttaaat tttaccttag aggctaatta ggtgtttagt
    27301 caaagttaat gcctttagaa tacaaatgta ttctaaaggc atttttacta tgtattttca
    27361 tttatattac taaacattat ctatttttat atacatttct atgtatttta ttttcatcaa
    27421 atcggtctat aaactcattt ttttcttcac tatatccaat agatataagt gcataaggaa
    27481 ctaattttaa tggtaagtct aaagtttgtc taactttatt taccacttta tttttaggaa
    27541 atactcctgc ccaacaagca gctagacctt gattagtaac ttctaataat aaattttgtg
    27601 tgcaagcacc taaatcttgt atccatttac caggttttaa gaatttatct ctatttccaa
    27661 gcactactat acataatggt gcaaattcta tatgctttgc tctatgctgt gactttgaga
    27721 gctctttcag cagttcctta tcatctacta taataaattc ccaaggttga gcattttttg
    27781 atgaaggtgc ttgcatagct gattttagta tttcagttat tttatcttct tctatatttt
    27841 tatctatata tgttcttatt gaacgtctat tttttataac ttctaacata cagattctcc
    27901 tttaaataaa attatttcta tttatataat atcattactt taaattttag ctattactta
    27961 tataaaaaat aaactttgtg ttggttttat ctaagtaaaa gtaacattca gaactaaaaa
    28021 acaagactat aaatccaaag tattaattaa aaaagaagta ataaaaaata atatacaaga
    28081 tttaaaaaag agtattgggc ttaaaattta attagaaaac caattttgag ataatctgtt
    28141 ttttatttta acaaaaaaac ataaataaag ttcgatacgt agcgaatgaa aaaattacaa
    28201 gaaatatttt ttttaaaaaa tttcaaaaaa gagttgataa tatatgtata ttaatataaa
    28261 atttaaggtg tataattcgt ataataatac gaatgatttg tagtgtaaaa taacttataa
    28321 acggagaggg gaagtctaat gaaagtagca gtagttatgg gttcaaaatc agattatcca
    28381 aaattagaag aagggataaa actgcttgaa aaatatggaa tagaagttgt agcaagagca
    28441 ttatcagctc atagaacacc agaacaactt tcaatattcc taaaagaaat agaagatgat
    28501 actgatgtaa taatagcagc agcaggaaaa gcagcacact taccaggtgt aatagcttca
    28561 caaacattaa ttcctgtaat aggattacct attaaatcat caactatgga tggactagac
    28621 tcacttttat caatagttca aatgccaaaa ggaatcccag ttgcaacagt tacaatagac
    28681 ttaggtttaa acgcagcttt attggcatta caaataatga ctttaaaata cccaaaatta
    28741 aaagaggatt tgaaatcata tagagaagag atggcacaaa aggtgttaga agacgacaag
    28801 aatttaaggg ggtagcagaa atgttattat atgaaggaaa agcaaaacaa gtatattcta
    28861 cagataatga aaatgaatat gttgtttatt ataaagatga tgcaacagca tttaatggag
    28921 aaaaaaaagc agaaatatct tcaaaaggta tactaaataa taagatatca acaataatct
    28981 ttgaaatgtt aaaagaaaat aatataaata ctcactttat aaaaagttta tcagatagag
    29041 aaatgttagt taaaaaagta gagattttac cattagaagt aatagtaaga aatattgctg
    29101 ctggttctat ctgtaaaaga gttggtcttg aagaaggtgt agttttcgat gagccaattt
    29161 ttgaaataag ctacaaaaat gatgcttatg gtgacccaat gctaaatgat gattatgcag
    29221 tggcaatgaa gttagcaact agagaagagt taaaattctt aagagaagaa actttaaaaa
    29281 taaacgagtt actaaaagca tttttcttaa aattaaacct aaagttagtt gactttaaaa
    29341 tagaatttgg taaggattct gaaggaaata taatattggc agatgaagta tcaccagaca
    29401 cttgtagact ttgggatgta aatacaaatg aaaagttaga taaggacaga tttagaaaag
    29461 accttggaga ccttgtagaa ggttatacgg aagtactttc aagaatgaat aataaatagg
    29521 aggcaaatgt atgtgtggag ttttagggat ttactctaat aaagatgtaa ctaaagaact
    29581 atattattct ttatattcta tgcaacacag ggggcaagaa agctgtggtt tagctctttt
    29641 agatgatgga gaaattaagt acaaaaaaga tatgggatta gttggagatg tttttaagga
    29701 aaatgaatta tctaagttaa aaggaaatat agggattgga catgttagat attcaacagc
    29761 tggaggaagt catgtttcta actgtcaacc tttagttgga agttgtagaa aaagacaatt
    29821 agccatagct cataatggaa atctagttaa tgcaaattat ttaaaagata tgctagaaga
    29881 agatggatat atgttccaaa ctaattcaga tacagaagtg attttatata tacttgctag
    29941 atattacaaa ggggatatag tagaaagttt aaaagtgaca atggattata taaaaggtgc
    30001 atatgctctt gtaataatga gtcaagaaga attggttgca gttagagacc cacatggatt
    30061 cagacctctt gtacttggta aaaagggtga tgaatatata tttgcatcag aaaattgtgc
    30121 aatagatata cttggcggag aagttataag agatgtagag ccaggagaga taatagtagt
    30181 caaagatgga gaactaaaat catattttta ttcagaaaat tataaaccag ttaagaaaag
    30241 ttgtatattt gaacacatat actttgcaag aaatgatgca actatagaca atgtaaatgc
    30301 atatgaattt agaattaaat gtggtgagag attagctcag aatgaaactg taaaggcaga
    30361 tatggtagtt ccagttccag attcaggttg gccaggagct attggttatg caaatgctag
    30421 tggattaaaa ataagtgaag gcttagttaa aaatagatat gtaggaagaa catttataaa
    30481 acctacacaa gaagaaagag aaatagcagt aaaaataaaa ttaaatcctc tttcaacaat
    30541 aataaaagga aaatctataa ttttagtaga cgactcaatt gtaagaggaa ctacatctaa
    30601 acaattagta aaatctttaa gagaagcagg agcaaaagaa attcatctta gaataacttc
    30661 tcctccagta gcttactctt gttactatgg aatagatact ccaaatcgct ctaaattaat
    30721 tgcatcaagt aacaacgtag aagaaatgag agaatatatt ggatgtgata gtttaaaatt
    30781 cctagatata gaaggaatgt tagatgcaac agaacataaa tctactttct gtaaagcttg
    30841 ttttgatgga gaatacccag ttaagaaaat tgataaggag gaactacttt catgttaaca
    30901 tataaagaat caggtgtaga tatagatgaa ggaaatagag cagtagacct tataaaaggt
    30961 aaaataaaag gaacttatga tggaaatgta gttggagatt taggtaactt cagtggatta
    31021 tacagtttaa aagattttgt aggtatgaaa gaaccagttt tgcttgcatc tacagatggt
    31081 gttgggacta agttaaaaat agctcagatg atggacaagc atgatactgt tggaatagat
    31141 ttagttgcaa tgtgcgtgaa tgatttaatt tgtcaaggag caaaaccatt attcttcctt
    31201 gactatatag ctcttgggaa attagtgcct gagcatatcg aaaaaatagt tggtggaatt
    31261 gcagatggtt gtaaaatgtc tggttgtgca ctaattggtg gagaaactgc tgaaatgcct
    31321 ggaatgtatg gagaagatga ctatgattta gcaggatttt ctgtgggaat agcagacaaa
    31381 gaaaagattg tttctggaaa caatgttaaa tcaggagatg tattggttgg tatatcttca
    31441 agtggagtac acagcaatgg attttctttt ataagaaaga tatttttaga aacttacaat
    31501 tataaaatgg aacaatatgt tgaagaacta ggaatgacag ttggagaagc acttttaaca
    31561 ccaactaaaa tatatgttaa attagcttta gatgtattag ctaaacatga cataaaagct
    31621 atagctcaca taactggtgg agggcttata gaaaatataa caagagttat acctaaagga
    31681 ttaggactag atatcaataa aaaatcttgg gagaagcctc ctatatttaa aatgatagaa
    31741 ggttttaatg ctgttgatga gagagaactt cataagagtt ttaacatggg tattgggcta
    31801 gttttaatag tagataaaga aaatgctgat gatgttgtaa actttataaa taatagagaa
    31861 aatgacaatg ctgattatgt agataaaaaa tatagtgaat tattagaaga taaagcttat
    31921 ataattggtg aagtagtaga tagtcatgaa ggtgtagaat tatgctaaat ataggagttt
    31981 taatatctgg tggaggaaca aatttacaag cagttataga tggtactgag tctggagaaa
    32041 taaaaggtca ggttaaagta gttatctcaa gtaagcaagg tgcttatggg ctagagagag
    32101 ctaaaaatca taacataaaa gcaatttgtg aaactgatga agacaagata atagaaattc
    32161 ttaaggaaaa taaaatagat ttagtagttt tggctggtta tttaaaaata atcagcccaa
    32221 agctggttaa tgagtttaga aacaaaatga taaacataca tccatcatta attccttcat
    32281 tttgtggagc tggattctat ggagaaaaag ttcaccaagg tgttatagat tacggagcta
    32341 aagtaactgg tgctacagtt cattttgtag atgaaggtgc tgatactgga ccaatcataa
    32401 tgcaagatgt agttaaggta aatcaagatg atgatgcaaa gacacttgca aaaagagtgt
    32461 tagaagttga acataggatt ttaaaagaaa gtataagtct tttttgtgaa aataaattaa
    32521 aacttcaagg taggagagtg tttataaatg agtaagagag ctttaataag tgtaactgac
    32581 aagactggtg tagtggaatt tgctaaagag ttaaataaat tagattatga aattatatct
    32641 acaggaaata catttaaaac attaaaagaa aatggtgtta atgtaatgca agttgaagat
    32701 gttacaaatt ttccagaaat attagatgga agagtaaaaa cattaaatcc atatatacat
    32761 ggtggtatac tttataaaag agataaagaa tctcatgtag aaactgtaaa tgaacacaaa
    32821 atacattcaa tagatttagt agctgtaaat ctatatgatt ttgaaggaac tttaaaagct
    32881 ggaaaaagtc atgatgaaat aattgaaaat atagatattg gtggaccatc tatgatacgt
    32941 tctgctgcca aaaactataa ggatgtaata gtagtagtag atataaaaga ttatgattct
    33001 ataatagaaa aattaaaaac agatacaatg acattagaag acagaaaaaa attatcatat
    33061 aaagctttct caactacagg aagatatgat gcgttaatat ctagttattt tgcaggagaa
    33121 gttggagata cgtatcctga catattaaat ttaactttcc aaaaagaaca aactttaaga
    33181 tatggagaaa atccacatca aaatggtttc ttatattcac agtcaaatgc aaaaaatcca
    33241 atcttaaatt atgagcaatt aggcggtaaa gaactttctt ttaacaactt aaatgattta
    33301 catggatgtt tagaagtaat gagagaattt aaagatagtg aagaagtagt ttcagtagct
    33361 ataaaacatg ctaattcatg tggggtaggt ttaggaaaag atgcttttga agcatataca
    33421 aaatgttatg aagcggataa ggtttcaata tttggaggaa tagtaggaat aacttctact
    33481 atagataaag ctacagcaga gaaattaaat gaaatattct tagaaatagt agtagcatat
    33541 gattttgaac cagaagcttt agagatactt aaacaaaaga aaaatctaag aatattaaaa
    33601 ttagctaaaa tagaaaatag tttacaacca tatgaaatga aatatttaga tggaaaatta
    33661 ttgatacaag atagaaacaa tatattagca gaaaaaagtg aaaatgtaac aaaggaaaaa
    33721 ccaacagatg cacaacttaa ggacatggaa tttggtatga gagtagtaaa aaatatgaaa
    33781 tcaaatgcaa ttgcagtagt aaaaaatgga caaactctag ctttaggttg tggacaaaca
    33841 tcaagaattt gggcattaaa aaatgctctt gaaaataaca aagataaaga ttttacagga
    33901 gctgttttag cgtcagacgc atttttccca tttgatgatt gtgtaacatt agctcatgaa
    33961 tatggaatat cagcagtagt tcaaccaggt ggctctataa aagataaaga ttcaatagaa
    34021 gcttgtgaca agtatgatat ggttatggta tttacaggaa taagacactt caaacactaa
    34081 ggaggatatt atgaagatat tggttgtagg cggtggcgga agagagcatg ctatatgctg
    34141 gaaactaagc aaagaaaaaa atgtagaaaa aatttattgt gcaccaggta atgcaggaat
    34201 tgcaaacgta gcagaatgtg taaatatagg tgatactaat atagaagaac ttttaaaatt
    34261 tgccaaagaa aatgaaatag gtctgacaat agtaggacca gaagtaccac tagttatggg
    34321 aatagtagat gagtttgaaa aagaaggatt aagagtattt ggacctaata aaaaatgtgc
    34381 tcaacttgaa ggaagtaaag ctttttcaaa agaatttatg ataaaacata acatacctac
    34441 tgcaaaatat aaagaatata caaacttaga agaagctata tcagaaatag atagttttgg
    34501 atatccagta gtaataaaag cggacggatt agctgctgga aaaggtgttg taatacctga
    34561 aaatagagaa gatgctatag caactttaaa agaaatgatg tcagataaga agtttggagc
    34621 tgctggagat aaaatagtaa ttgaagagtt tttaaaagga atagaaactt caattctagc
    34681 atttgtagat aatgatacaa tagttcctat ggcaagtgca aaagaccata aaaaagtaaa
    34741 caactatgag caaggtccaa acactggggg aatgggaact ttttcaccta gtgaaatata
    34801 tacagaagaa ttagcaaata aagtaaaaga gacagtatta gaaaaaactt tagaaggctt
    34861 caaaaaagat ggacttaatt ttaaaggtat tttatttgtt ggtcttatga taactgaaga
    34921 tggagaaaaa gtacttgaat ataatgtaag atttggagac cctgagacac aatctgtttt
    34981 atttagatta gaaacagatt tacatgagat aatggaagct atactagata ataagttaaa
    35041 agatatagaa ataaactata gtgatgatga agctgtatgt gttatgctta catcaggagg
    35101 gtatccagac agttatgaaa aagggaaaat tataactggt cttgaaaact tggatgatga
    35161 tatagtagta ttccatagtg gcactaagat gtttgatggt aatttggtta ccaatggagg
    35221 aagagtaatt ggtataactg caaagtcaac tacagttaag gatgcagcag aaaaagttta
    35281 tgaaaacata aagaagataa actttgaagg aatgcactat agaacagaca taggaagata
    35341 atttttctaa aatggaggat aaggtatgtt gaatactgaa aataaagact caatggttag
    35401 aagagtatta gttgaaaaaa gagaaggttt tgaccttgag gctaaagctt taaaaaaaga
    35461 cttagtagaa agtttacaca tagataatat agaaaattta agaatattaa atagatatga
    35521 tgtagaagga atatcagaag aagtttatga aaatgcagca aagacaatat tctctgaacc
    35581 aaatttagat gtagtatatt atgaagaaat accaaaatta aatgatgaaa gagtatttgc
    35641 aatagaattt cttcctggtc aatacgacca aagaggtgat tgggcagctc aatgtgtaca
    35701 aattgtaaat caagggataa gacctgctat taatacagca aaagtttata tattatcagg
    35761 caaaataact gatgaagagt tttctaaaat aaaagattac tgtataaatc cagtagatag
    35821 tagagaagca tctttagaaa aaccagaaac gttaaaaatg gaaactgaaa taccaacaac
    35881 agttgaagta ttagatggat ttatagattt agatgaaaat ggattaaaaa catttgtaag
    35941 tgaaaaagga ttagcaatga ctttaggaga cttacaacac gttcaaaaat actttaaaga
    36001 tacagaaaag agaaatccaa ctataacaga aataaaagta ttagatactt attggtctga
    36061 tcattgtaga catactactt ttatgactga aatagaaaat gtaaagatag aagatggtaa
    36121 gtttaatgat atagtaaaag aagcgtatca aatgtatctt aactcaagag acaatgtata
    36181 tgtgaacaga cataaagata tatgtttaat ggatatagcc actgttgcag taaaagaatt
    36241 aaagaaaaat gggaaattaa atgacctaga tgaaagtgaa gaaataaatg catgtagtat
    36301 aaacgtagat gttgaagttg atggtaagat ggaaaaatat ctagtaatgt ttaaaaatga
    36361 aactcacaac catccaactg aaatagaacc atttggtgga gcagctactt gtttaggagg
    36421 agctataaga gacccattat caggaagaag ttatgtttat caagcaatgc gtgttacagg
    36481 aagtgctgac ccaagaacga ctttagaaga tactttacct ggaaaactta tgcaaagaaa
    36541 aataactaca gaagctgctc atggatatag ttcatatggt aaccaaatag gtcttacaac
    36601 tggacaagtt gcagaagtat atgatgaaaa ctttgttgca aagagaatgg aaataggtgc
    36661 agttatagca gcagcaccaa aagagaatgt agtaagagaa agacctgaag caggagatgt
    36721 aatcgttctt cttggaggaa aaacaggaag agatggctgt ggaggagcaa ctggttcatc
    36781 taaagaacat agtgaagagt caatcttaac ttgtagtgca gaagttcaaa aaggagatgc
    36841 tcctaacgaa agaaaaatac aaagattctt tagaaataaa gaagttgctc aaatgataaa
    36901 aagatgtaat gattttggag caggtggagt ttgtgttgct ataggagaga ttgctgatag
    36961 cttagatata aacttagact tagttcctaa aaaatatgat ggacttgatg gaactgagct
    37021 tgcaatttca gagtcacaag agcgtatggc agtagccata aaaaaagaaa ataaagataa
    37081 atttatacaa ttagcagtag aagaaaactt agaagctacg catgtagcta cagtaacaga
    37141 tacaggatat ttaagaatgt tctggaatgg aaaagcaatt gtagatataa atagagagtt
    37201 tttagataca aacggagtaa aacaaactac tgatgttcat gttactaaag tagatgaaga
    37261 aaatacattc tttagctcta atgaaatagt aaaagatgtt aagtgtgcaa gtatgaaaga
    37321 caagtttaca aaagtactat ctgaccttaa tgtttgttct caaaaaggat tagtagagat
    37381 gtttgataat acaattggtg gtaatacagt acttatgcca tttggaggaa agtatcaagc
    37441 gactccaaca caaggtatgg ttgctaagat accagtactt ggaggagaaa ctaatacttc
    37501 tacaataatg acttatggat acaatccaaa ggtaggaaaa tggagcccat tccatggtgc
    37561 cttgtatgca gtagtagaat ctgtgtgtaa attggttgct attggaggaa attatagtac
    37621 aacaagactt acattccaag agtattttga aaaacttggt aacaatccag aaaaatgggg
    37681 taaaccattc tcagcacttt taggagcatt ttatgcacaa agtaaatttg agatacctgc
    37741 tataggtgga aaagacagta tgtctggtac atttaaagat attgaagttc caccaacatt
    37801 agtttcattt gctgttgaca cagtagatgc gaagaaagta gtatctccag aatttaaaaa
    37861 agcagactca aaagtagtaa tgttatgtgt aaacaaggca gaaaatgatg ttgtagattt
    37921 tgaggaatta aagagaaact tagataaagt aagagaactt atacatggaa ataaagtttt
    37981 atcaacatat gcattaggat ttgcaggtgt aggtgaagca ataagtaaaa tggcttttgg
    38041 taataaaata ggatttaagt ttagtgaaga ggctgaaaaa gcatttacag atgataaatt
    38101 atttgaggct agttatggaa atatagtact tgaattagca aatgatgatt taagtatgtt
    38161 agaaggatac aattatgttg tgcttggaag tacagttaaa gaaactagta tatttatcaa
    38221 aggtgaagaa cttgcattag atgaattata taaagcacat tgtagtactt tagagcctat
    38281 attcccaact aaaacagaag aagtaaaatc aaagatagaa actataagtt atatatcaca
    38341 aggagaagct aaaaaatcat cattaagtat agctactcca agagtattta taccagcatt
    38401 ccctggaaca aactgtgaat atgactctgc aagagcattt gaaagagcag gagctaatgc
    38461 aagtataaga gtatttaaga atttaactta taaagacata gaagattcta tagatacaat
    38521 agtaaacgaa ataaaatctt ctcaaataat aatgttacca ggtggattta gtgctggtga
    38581 tgagccagat ggttctggta aatttatagc tactgtattt agaaatccta gagtgcaaga
    38641 agctataaat gaatttttaa ctcaaaaaga tggactaatg ttaggtatct gtaatggatt
    38701 ccaagtatta attaaattag ggttagttcc atatggagaa ataagagttc caagtgaaag
    38761 tgctccaaca cttacttaca ataatattgg tcgccatcaa gctaagattg ctagaactag
    38821 aatttcatct aataaatctc cttggttagc tcaaactaat gttggagata ttcataatat
    38881 agcaatttct catggagaag gtaagtttgt tgccagtgaa gatgttatga gagaattaat
    38941 tgctaatgga caagtagcaa ctcaatatgt tgactttaat aatgaagcta cttatgatat
    39001 tgagtttaat ccaaatggtt cattctatgc tgttgaaggt ataactagtg ctgatggtag
    39061 agtgtttggt aaaatgggac attctgaaag aattggtgag gaagtatata agaatattat
    39121 aggtgaaaaa gaccaaaaga tatttgaatc tggagttaaa tattttagat aaagctttga
    39181 tgtttaattg atagctagaa tatataattt agatatttag atttaaagag atgtaataat
    39241 atgatgataa tcatttaata ttacatctct tttttattta tctaagaaat aataagttca
    39301 acctaagtta aaatacaagc tgtgttataa ttaattatta agtaaaattg aatatttatt
    39361 ggagggcaac ataattaatg aaaatattaa taacagggtc taatggtcaa ttaggaaaag
    39421 aattggttaa ccaattagaa gcaatcaatc aaagtataaa ccaaccaaaa tatgttatat
    39481 tagctacaac aagaagtgat ttggacatat ccaatcagac taatgtagat aattttattt
    39541 tgcataataa acctgatgta gttgtaaact gtgcagcata tacaaaggtt gatgcatgtg
    39601 aagataatat cgaaattgca tacaaaataa atgctttagg agtgagaaat ctagcaatag
    39661 catcagaaaa agttaatgct aagcttattc acatatcaac tgactatgta ttcaatggtt
    39721 tttctaaata tccatataga gaagacaata aaactgaacc caattctgta tatggaaaaa
    39781 gtaaacttat gggagaaaaa tttgttgaac aattctcaca taagtacttt atattgagaa
    39841 cagcatggtt atatggtaat gggaataatt ttgtaaagac catgataaaa ctttctttag
    39901 aaaataaaga ggttaatgtg gttaatgacc agtttggaac tccaacaagt acagtagact
    39961 tagcaaaaat tataataaga atcatggaaa cagaacatta tggagtttat catgctacat
    40021 gtgaaggtga gtgtagttgg tatgattttg ccaaaaagat atttaaacta aaaaatatag
    40081 atataaaagt aaatccaatt aagagtaacg aatttaaatg taaggctcca agaccactat
    40141 attctgtatt ggataatttt atgttgaagt taattggttt aaattctttt agaaagtggg
    40201 aagaatccat tgaagaatat ttagaaagat atgatataaa tgaaaagtaa atgtattatt
    40261 ttgagaaaag aaaataagat attataaaaa atataaatat ttcttttatt tatccgataa
    40321 tcataatatg acaaaaacaa atttaaggat ggaaaaagat gaaaggaatt attttagcag
    40381 gagggtctgg tacaagacta tatcctataa caaaatgtat atcaaaacaa acacttccaa
    40441 tatacgataa accaatgata tattacccta tgtcggttct tatgttggca gggatacaag
    40501 atatattaat aatatctaca ccaagagata taaaagcatt tgaagaatta tttggagatg
    40561 gaagttcact agggcttaac ataacatatg caattcagga gaaagcaaat ggaattgcag
    40621 aagcgtttat aataggagaa gaatttatag gaaatgacag agtgtctctt gtattagggg
    40681 ataatatatt ttatggatat ggatttagtg aaaggttgga gaatgcagtt aaaagaaaag
    40741 gagcaactat atttgggtat catgtaagta atccaaattc gtttggagtt gtagaatttg
    40801 ataaggattt taatgtattg tcaatagaag aaaaacctac agttcctaaa tctaattatg
    40861 ctataccagg attatatttt tatgataatg atgttgtaga gatagcaaag ctagttgaac
    40921 cgtcagatag aggtgaatta gaaataacct ctataaacag tgaatatcta aaacgaggaa
    40981 aactaaaagt ggaacttcta ggaagaggta tggcttggct tgatactggt acacataaag
    41041 gtctattgga tgcttctaat tatgttgaag tggttcaaac aagacaggga ctgtatatag
    41101 catgtttaga agagattgca tatacaaaag gatatataag tagagaacaa ttaatgaaac
    41161 tagccaagcc actgataaaa actgaatatg gtcaatatct attaaaattg gctagtgaag
    41221 atatgtaata tggtagataa aatttattat aaattttatt aagggagttt attataatgg
    41281 gaaaaatcaa tgttataaag actaaaatag aaggattata tatagtcgaa ccaaatgtat
    41341 tttatgatga aagaggatat tttatggaaa gctataataa aaaggatttt atagagcagg
    41401 gtcttgatat gtgttttatt caagataatg agtctagctc aagaaaaggc gttttaagag
    41461 gaatgcattt tcaggttaaa tatcctcaag gaaaattagt cagagttaca gagggagaag
    41521 ttttcgatgt tgcagttgat ttaaggaaag attcacaaac atttgggaaa tgggaaggtg
    41581 taatattgtc tgataagaat aaaaaacaat tttatattcc agaagggttt gcacatggat
    41641 ttttagtttt atcagaaaaa gcagtattta gttacaaatg tacaaattat tattacccag
    41701 aatttgagaa tggctttata tggaatgaca agcaaatatc tattgagtgg cctttaaaag
    41761 gaattgaaga aatattttta tcagaaaagg acaaaaaaca aaaaagtttt aaagatattt
    41821 gtacaagacg ttaataaaaa tttattagaa ttaacattta ggagaaaaaa tatgaaaaaa
    41881 atactgataa ctggaggagc aggatttatt gggagtaatt ttatacatta tatgcttaac
    41941 aagtatgtag attattttat tgttaaccta gacttgttga cttatgctgg taatttagag
    42001 acattaatag aaatacaaga caattccaat tataaatttg ttaaaggaga tatttcaaat
    42061 agggagcagg tgtataagct atttgaagaa gaaaggtttg atatagttgt taactttgcc
    42121 gctgaatctc atgtagatag gtcagttgag aatcctgatt tatttattaa aacaaacatt
    42181 ataggaacac aagtactttt agatgcatct ataaaatatg gagttaaaag gtatcatcaa
    42241 atatctacag acgaagtgta tggtgattta ccaattgata gaaaggattt attctttaca
    42301 gaacaatctt ctatcaatcc aagttctcca tattcagctt ctaaagcatc agcagattta
    42361 ttggtaagtt cttattatag aacatatgga ttgttaacaa ctatatctag gtgttccaac
    42421 aattatgggc catatcattt tcctgaaaaa ttgattcctc ttatgatttt aaatgctttg
    42481 gaaaacaaac aattgccagt atatgggaat ggggaaaatg taagagattg gttacatgta
    42541 tatgaccatt gtactgctat agacttaata atacataaag gaaatatagg ggagatttac
    42601 aatataggag gtcataatga aagaagtaat ctagaagtag taaaaatgat attaaatctt
    42661 ttaggtaaat ctgaagagtt aatatcctat gtaaatgata gacctggtca tgatttaaga
    42721 tatgctattg atgcaactaa aatagagaat gagttaggtt ggaaggcaaa atatgacttt
    42781 gatttgggta taaaagaaac tgttaagtgg tatatagaaa atgaatcttg gtggaaagct
    42841 gttttatcag tataacttta aaatttagaa aggggcgttt tatattgaat gagataagtt
    42901 cactaattaa tatattagca ttgactcaat tatctggtag taatactaca aatcaatgta
    42961 attgtacata taataattca tctggatttg atatgattat gatgaccttg ttaaaagcat
    43021 tatcacaaaa taatcaacat acttctaata gctacaattt attgtctaat tctgagaatt
    43081 tatttaatga acttgataat gtagtaaata ataccactag tagatttata gatgttgata
    43141 caaaagataa aaatgtaaag ttgagaattg aaaatgctgt agatcaagca tcaaaaaaat
    43201 ataacgtaga ttcaaatctt ataaaagcaa taattaaagt tgaatcagat tttaatccaa
    43261 ataccgtttc ttctgctggt gctaagggtc ttatgcaact tatgccagaa aactgcagag
    43321 acttaggagt tacagaccct tttaatatag aacagaatat agatgctgga actagacata
    43381 ttaaggaata cattgatatg tttggaggga gcatagaaat gggattgatg gcatataatg
    43441 gtggtcctgg aagaatgaaa agtagaggag tagaatcaat ctctgacctg tataaaatgc
    43501 caaaagaaac acaaaattat attcctaagg ttatgaaata ttatagaggg taggctttat
    43561 tatgggaata aatatagata agctaaacat aagtccaagt ataaatatgg aggttaaaaa
    43621 actaaaagag agtaataaat tttctgacaa attaaactct ttaaaacaat cttcttcatt
    43681 ggaagatata aaacgaaatt tggaaagtgt aaaaaaggca ggagaaaggc ttgtacttac
    43741 tcaaaactat ggcgatatta gtatatataa aaatgcagta aaagaatacc taaaatctgt
    43801 tgtagataat atgtattcac ttgataaaaa tagtagcttt tgggagcatc agtattataa
    43861 gaatgtaaag attgttgata gtaaacttga ggatatgact agtaagttaa ttagtgaaga
    43921 aaaagaaaac atagatattg tttctactgt tgacatgata caaggcttat tgatagatat
    43981 gtatagataa ggttatacaa ggagaaaaat tttatgaata gcaaaaaaga ggatatatat
    44041 gaattgaatt ttgggcaatt aatagaagaa aaatctggtg ttatagaaga aaatcaaaat
    44101 gtttttaatg caaaagtaaa tgtagctgtt tctataggaa atacaacaga aacaataaaa
    44161 aatatattag atttaaaaga aggctctata ataaaattaa gtaagaatgt ggatgaaaaa
    44221 ttagatatat atgcaaacga tagattgttt gcttatggag aaagcattat tacaaatgag
    44281 aggttatctg taagattatc taaaatagaa gatccagatg taaattagca ttttaaatag
    44341 tatcccttta ggctattctg tatgagttta gctaagggga tatttttata aaaaatttaa
    44401 aatatgtgtg aattatataa atatttttat tttatgagcg ataactaaat tataagtatg
    44461 taattttgga ggtgaaacta tggatattaa aaatgtaagt tcaaacattg tagtgaataa
    44521 ttatttaaag aatacatctg gtataaaaaa agtggaagag gttaaaaaaa ttaataaaac
    44581 agacaagata gagttatcta aatttgcaaa ggaaatggca agtgtgtcaa atatgagtga
    44641 tgagaatatt agaaataaaa aagtcgatga aataaaaaat gcattagaaa atggaactta
    44701 caaaataaaa ccaaaagaaa ttgcgaaaaa aatgatagag gatatgcgag gataaagtca
    44761 tgattacaga cttaaaagtt ataatatatg aagaaaaaaa tataattagt aagatgatgg
    44821 aattattaaa agaacaattt gattatatag ttgaaaaaga cttagaaaat ttaaatatgt
    44881 taaatcctaa actagaagat attagcaggg agcttgcatc catagaaata aagagaagac
    44941 aactttttgg tgatgatatt tcaatgagtg aagttgttga aaatagtaat gatggatact
    45001 taaaagaaat atatacagac ttgaaacaca ttcttgcttt agctaaaaat caacaagaat
    45061 caaatgattc tctaataaag aaagaactta tttttacgaa aaaaatgatt aatttcataa
    45121 aaccagctga taagaaaact acaacttata attcttatgg aaatattaga aaataaatat
    45181 taggaggaga aatatggcag gattattttc cattttaaat acagctaatt caggaatgaa
    45241 tgcgcaccaa aaagcaatac agacaatttc tcataatata agtaatctag atacagacgg
    45301 ttattctagg caaaggaccg agtttgccac aaatagtcca atgtatatgc ctagtttgag
    45361 taattcaatt gcaagaggac aattagggac tggagtacat gtaacggatg taacaagagc
    45421 tagaaatagt ttttatgatt accaatttag ggcagaagct cataagtatg gtaagacagt
    45481 ttcaaaatat gattattaca atactataga aactatacta aatgaaccat cagactatgg
    45541 aatatctgca ggtatagatg atttttttaa aggatgggag tcattatcaa aggatataaa
    45601 tagtgacagt aaaaaaagtc tagtggtaga aaacgcatct aatttagcaa ctttaataag
    45661 tgaaagttat aagaagcttg ataagttaaa agaagatata gattctaata tagacactga
    45721 gataaaacaa ataaatgaca tgttaaaaag tcttgaagat ttaaataaat ctattgatat
    45781 tatatctggt tctggctcta caccaaatga tttacttgat gaaagagata gaattttaga
    45841 taacttgagt tttaaactag actttgaaaa tagtgatgtt aaaaatatgc ttgcagatgg
    45901 taaattagaa cttaatgaat taaaaaatcc agatggaact tggaaaacag gtatatcagg
    45961 gaccttacaa ggcttgtttg aaatgcatgg taagattgat acatataaaa gcgatttaaa
    46021 agatgtatct gatggattag ctaaacagat aaatgatgtt tataatacgt ctgcaggaat
    46081 aacagtaaca gattttttta taacttcaaa tgtagatggt gaagatatta taaagataaa
    46141 tccagctata aagagtaacc caaatgaatt aaagcttact gctgatgaag cttcaaaaat
    46201 tgctaagtta aaggatgaaa aaatagatat tggggtggct ggtggaaaag taagtacaat
    46261 aagtgaccac tataaagcct ttgcagaatc aatcggttta gattctcaaa aagtaaatca
    46321 agatgaagca aatcaacgta aaattataaa taatattgat aactcaagaa tgagtgtttc
    46381 aggtgtatct ttggatgaag aaatgacaga gcttataaaa atacaacgtt catatcaagc
    46441 tagtgcaaaa gttatgtcaa cagctgtgca actactggat gttgtaataa atggaataat
    46501 ttaatagaag ggggaattta taatgagagt cagtacaggt atgatgtcta gcagctatct
    46561 aaactcacta caagataatc tacaaagatt ggataaggtt aatagacaag ttaatacaac
    46621 aaaagaaata aacaagctat cagataatcc atataaagca ataaagatat taaactcaaa
    46681 aagtgaaata aagactatgg agacttatgt tgagaattgt aaagatacag ggaattggtt
    46741 agaaactact gatactgcat tagatcagct tggaaaatta ttatcagaca taaagaaaac
    46801 tttggtggca agtggtgatg gtgcatactc agatgatgaa ttaaagactc ttagtaatga
    46861 aactaatgaa aaaatgaaag aaattgcaaa tgctttaaat gcaacacatg aagggaagta
    46921 catattttca ggttcaaata cgggggtacc acctgttgaa tgtatagata atgctgatgg
    46981 ttcagtgagt ttaaagttta attctagtct aaatcttaat aaattaaatg actctttgag
    47041 tatggatata gctcaaggaa taagtgtaga ttataacgtt aaattgagta gccttggatt
    47101 tgacccaaca aaaactgacc catttgaaga gttaaataac atatcaaaaa aattagcaaa
    47161 tccagatgct gatgctataa aagagcttac aacaacttgt ttgggcgata tggaacaact
    47221 aatagaaaat acagtaaatg ttaggtctat atatgggaca aaagcaaata cagtagaggc
    47281 tatgaaggaa aaaaacgatg atagtttgat acagttaaag gatattttgt cacaaaatga
    47341 agaaatagat tatggtgaaa aacttgttca attaaaggca gcagagttaa cttatcaagc
    47401 ttcactacaa acaggaggaa agttatttaa tgtatctata ttagattaca tataataaaa
    47461 taacgcagat atgatgaagg ttacattaaa aaaaggtata ttaggttttg aaaatttaaa
    47521 agaatatgag cttttagata tagaagataa tgattattta aaagaattta attctactga
    47581 agaagaaggt ataggatttg ttgttgtatc tccatttgag attatcaatg aatatgaaat
    47641 agttttaaat caggaaacaa tagaaaaact agaagtgaaa tctccaaagg atgttgtatt
    47701 atttaatata attactcttg gtcagacatt tgaagaatca actgtgaaca tgaaagctcc
    47761 tatagtgata aatataaaaa ctaattttgg aatgcaaata attttacagg atgataaata
    47821 ttcaataagg catccattat tgagaggtga tagtggatgc tagtaatttc aagaaaaaaa
    47881 gatgaagcag tacttatagg agaaagcata gaagtaaaaa ttgtaggggt agatggaaac
    47941 aatgtgaaac tagctatatc ggcgcctaac aatataagta tattaagaaa agaaatatac
    48001 gaaaaagtaa agagtgagaa tataaaagct acaaataaaa atataaaaat tttaaagtca
    48061 ttaaaataat aagcttggag gaagtaatat atgtatggag aaaatcctta taattcttat
    48121 aaacaaaatg ctgtttttat ggcatcaaag gaacaattgt tacttatgct tgttgatgga
    48181 gcagtaaaat ataccaaaat agccagagca gctatcttag ataaaaatac acagaaagcg
    48241 catagagaac ttgtaagagt tcaggatata tttacagaac taatggttac attagaccaa
    48301 aatgcaggac aatgggcaaa ggatatgtac aaagtttatg attttgtaag atatgaactt
    48361 tcaagagcca atattagaaa agacatccag gtaatagata atgtgttacc tgtaatagaa
    48421 caaattaaag atacatggca tgaagctgat aaaaaaagta aagaagaaag aagtaggtac
    48481 aaataatgga attaaattta gctgaattag ataagttatc aaaagaggaa ttactattga
    48541 tgcttgtaga tggcacagta aaatatacca atatatccaa agaagctctt ttaaataacg
    48601 actatttgaa agcacataat gaacttgtaa gagttcaaaa tatatttaca gaactaatga
    48661 ctacattaga ccaaaatgca ggacaatggg caaaggatat gtataaagtt tatgaattta
    48721 taaaatctga attagcaata gctgatgaaa ataaagatat taaaataatt gatgatatat
    48781 tgccaatagt aaaacaaatt agagatacat ggcatgaagt ttacaatcaa ctaaaaatat
    48841 aattagatgg agggataaag gtatgtcaag tataagtcct ataagagtta caggtctttc
    48901 aggaaatttt gatatggaag gcataatcga agctagtatg attagagaca aggaaaaagt
    48961 tgataaagca aaacaagaac aacaaatcgt taaatggaag caagaaatat atagaaatgt
    49021 tatacaagaa tcaaaagatc tttatgataa atatctaagc ataaattctc ctaatagtat
    49081 agtaagtgaa aaagcatact cttctacaag aataaccagt tctgatgaaa gtattatagt
    49141 agcaaaaggt tcagctggtg cagaaaaaat aaattatcaa tttgcagttt ctcaaatggc
    49201 tgaaccagca aaatttacta ttaaattaaa ttcaagtgaa cctattgttc gacagttccc
    49261 tccaaatgcc agtggagcta gttctttaac tataggagat gtaaatatac caatatctga
    49321 acaagatact acaagtacta ttgtaagtaa gataaactcc ctttgcgcag ataatgatat
    49381 aaaggcttct tatagtgaga tgacaggtga attgattatt tcaagaaaac agactggttc
    49441 gtcatcagac attaatttaa gagtaattgg aaatgacaat ttagctcagc aaattgctaa
    49501 tgataatggt atcacattta taaatgatgc tggtggaaac aaatttgcaa atgtatatgg
    49561 aaagaatcta gaagctgatg taactgatga acatggaaga gtaactcata taagtaaaga
    49621 acaaaattca tttaatatag ataatattga ctataatgta aattcaaaag gaactgcaaa
    49681 gttgacttct gtaactgata ctgaagaagc tgttaaaaat atgcaagcat ttgtggatga
    49741 ttataataaa ctgatggaca aggtctatgg tttagttact actaaaaaat caaaagatta
    49801 tccacctctt acagatgccc aaaaagaaga tatgacaact gaagaaatag aaaaatggga
    49861 aaagaaagct aaagaaggta tacttagaaa tgatgatgag ttaagagctt ttgttgaaga
    49921 tattcagtct gcattttttg gagatggaaa aaatattatt gcattaagaa aactaggtat
    49981 caatgaaagc gaaaattaca ataaaaaagg tcaaatatca tttaatgcag atactttttc
    50041 aaaggctctt atagatgata gtgataaggt atacaaaaca ctagcaggtt attcttcgaa
    50101 ttatgatgat aagggaatgt ttgaaaagct aaaagatatt gtatatgaat attctggaag
    50161 ttcaacttct aaacttccta aaaaagcagg tatagaaaaa actgcttctg ctagtgaaaa
    50221 tgtatattca aaacaaattg cagagcaaga aagaaatata agcaggttag ttgaaaaaat
    50281 gaatgataaa gagaaaagac tttatgctaa atattcagcc ttagaatctt tgttgaatca
    50341 gtattcttcc caaatgaatt atttctcaca agcacagggt aattaattat ggataaatta
    50401 aaagaaaaat taaatttata taaagatata tctttacaaa ttataaattt gattgaaaag
    50461 gaagaatata taaatataag tagtaagtta ggtgaaagac aagagattat aaatagtgta
    50521 agtgaaattg atagaaatga ttttatacag ctttataata gaatggaatt aattgaaatt
    50581 gatagtagga taagagatat tttacaagga caattattag aagtaaaaaa agaattacat
    50641 gagtataagc ttactaaaca agtgaacaca atgtattata acttaaatag agaaaaagta
    50701 aatattttta ataaaaaagt ataaagttat gtaccatctt gtccgattat ataaatgaag
    50761 aattaataaa aaagattaaa agtagaaatg acaaggatgt caactatact aaggagggta
    50821 aaataatgag agttaataca aatgtaagtg ctttggtagc aaataaccaa atgggaagaa
    50881 acgtaaatgc acaaagtaag tctatggaga agctatcttc tggtgttaga attaagagag
    50941 ctgctgacga tgctgctggg cttgctatat ctgagaaaat gagagctcaa ataaaaggtt
    51001 tagaccaagc aggaagaaac gttcaagatg gtatatctgt tgtacaaaca gcagaaggtg
    51061 cattagaaga aactggtaac atactacaaa gaatgagaac tttatcatta caatcttcaa
    51121 atgaaactaa tactgctgaa gaaagacaaa aggtagctga tgagttatta caattaaaag
    51181 atgaagttga aagaatatca agctcaattg agtttaatgg taagaaatta cttgatggaa
    51241 gttctacaga aataagatta caagttggag caaactttgg aacaaatgtt gcaggaacaa
    51301 ctaacaacaa caatgaaata aaagttgctc tagtaaatac ttcaagtata atgagtaaag
    51361 caggtataac aagttctaca atagcaagct tgaatgtaga tggagcttct ggaacagatg
    51421 cagctaaaca aatggtgtct agcttagata tggctcttaa agaattaaat acatcaagag
    51481 caaaattagg ggcacaacaa aatagactag aatcaactca aaacaactta aataatacta
    51541 tagaaaatgt tacagcagct gaatcaagaa taagagatac agatgttgct tcagaaatgg
    51601 ttaacttatc taaaatgaat atattagttc aagcatcaca gtcaatgctt gctcaagcta
    51661 atcaacaacc acaaggagtt ttacaattat taggataaaa taattttgta tattggatat
    51721 agaagaaagg gtaaggcttt gctttactcc tttctttttt tacaaatata cttttgaaag
    51781 gaaaatttat atgttactta gtatagttat gattgttaaa aatgaagaaa aaatacttga
    51841 aaaaacttta aaatcattaa ccacattaag aaattctata gaaagtgaac ttataatagt
    51901 cgatacaggt tctacagatg atactataaa tatatctagg aaatacacgg aaaatgtgta
    51961 ctttcataat tggaataatg atttttctag tatgagaaat atatcaatat cttatgccaa
    52021 gggcgaatgg ttacttatat tagatgcaga tgaaatatta attgattctt caactattgt
    52081 aaaatttttc aaggacggtc ttgataaaaa atttaattct gcttcaatac aattaaaaaa
    52141 tctttactca tacgataaaa aattatatgg atattgttcg gtgcttagac tttttaaaaa
    52201 cgttgatttt agataccatg gtaaagtaca tgaacaacca atatacaaaa atcctatatt
    52261 taataatgtt gctgattttg aacattatgg atatttgttt gaagatgaag aaataagatt
    52321 aaataaggtg aaaagaaatg aaaaactatt atttcaagag ttaaaagaga atgataattc
    52381 tccatataca aactatcaat tggggaaaaa ttttattata ttaggaaaat atcaggaggc
    52441 tttatactat cttgagaaat cttatgaatt atattctaaa ctagaatcgg cacctggtta
    52501 cttgataaca agccttgtaa aaacatattt atatttagga aaacataaga agtgtgaaaa
    52561 attgtgctta aagtatatta agaaagacat gaataatatt gatatatatt attatattgc
    52621 acaagcacaa gtagatttag gaaagtatga aaatagtata gattcgtata agagatatat
    52681 ttacttgtta gataattatg aaataagtac acaagcaaat agtttatttt cagacactga
    52741 tactgtaggg cttagagatg aggctattat tacactgata aagatttatt ataagcttga
    52801 aaaatatgag tttgtaattt cagagtacaa taacattgaa gatgtggaaa agaaaaagaa
    52861 tgtgtacttt agcttattta tgtccctata taaattgaat agatttgaag atataaaaaa
    52921 ttattataaa gaagtttcaa attctaaaat tgaaaaaaat agtttttata gaaatataga
    52981 agaagttata aataatatta aagaggatga aaaagagtat gtatataaaa tcctttgtga
    53041 cattgagggt aattatggca ttttaaatca aataaggata aataaatgtg tatctataga
    53101 taaatgtaaa gaaatactca atgaagaaaa ggaaataatt tatgcatata ttataaaaat
    53161 agcttttgaa gagaagattg atttactaga tattttttat gaaatggaat atgtatggat
    53221 agagaaatat ctaaaatatc ttttagcatt agaaagaagt tttaatttag tactatataa
    53281 gtacataatt agtcgtcaaa atacatcaga tatggaaaag ataagagtat ataaagctat
    53341 atctaaagta gttttagaaa gtataagctt aagtgatgaa aaatataagg agatttttta
    53401 tttttatata atgtattctt ataagtatat aagatacata tatagcaatt taagtgattt
    53461 tgaattaaaa aaatttgttt gcaatgattt agataagttc actatagaat ttaagcatct
    53521 acttgacatt aaaaataaag taaataatgc taatgaaaaa ttagagtata tacatagtat
    53581 gaggaaatta ctaaatgagt atccttttta taataaaata ataaaaatac ttatatgtga
    53641 attagaagaa aatataaaag aaagtgaaga atttaaggat ttaaaagata gttttattat
    53701 tagtatagaa aatatgattg aaactggcaa aataaatgat gcgaaattat tggtagatga
    53761 ctattcaaaa acatttgtgg atgatataaa gattttaaat ataaagggaa ttttatacat
    53821 gcttgaaaat aagcttgata aagctgattt tatgttaaaa aaggcattat cattagatgt
    53881 agaaaatgaa gatactatat ataatataga atacttaaaa agcttaagat aagtcaaaaa
    53941 taggagaatt gaagaatgaa tataccaata gtggttaatg aaaaatctaa agatataata
    54001 aaagattggc aatatacgtg tacaaacgaa gatataaaat ttacaagcat aataatattg
    54061 acatataatc aaatagaata tactaaatta tgtattgaaa gtattaggaa atttacccca
    54121 aagaataaat atgaaataat aataattgac aataactctt ctgatggaac agttgagtgg
    54181 ttaaagagac aatctgatat aaaatctgtg tataataaca aaaacttagg atttccaaaa
    54241 ggatgcaatc aaggtattga attagctact ggtgaaaaca tattgttgtt aaataatgat
    54301 gtaatagtta ctccaaattg gctctataat ttgaataaag ctttatggtc tcaagataat
    54361 ataggtgctg taggacctat tacaaatgca tgttcatatt atcagcaaat tgatgttgat
    54421 tataagtcaa ttgaggacat gtttatattt gcacacaaaa taaataaatc tagtattaac
    54481 ctatggaaat atagattaaa gttagttgga ttttgcatgt taataaaaaa aactgttctg
    54541 gataatgtag gggttttaga tgaattattc acacctggaa attttgaaga tgatgattta
    54601 tcttttagga tgatagagtc aggatataag ttattattat gtcaggatac ttttatacac
    54661 cattttggaa gtgtgtcttt taaagaaaat cgtaataaat atacggatat aatgtatatt
    54721 aatagaagaa aatttgaaac taagtgggga tttaatccag aatatagtgg aatgataaga
    54781 acagatttga tttctaaaat agatgatagt ttggaggcaa atattaatgt tttagaaata
    54841 ggctgtggta taggggctac tcttttagaa ataaaaaata tatataaaaa tgcatcaata
    54901 tatggaatag aaattagtga gtcagcaggt aaacttgcaa agtatagtgc agatgtactt
    54961 atagcagata tagaaaaagt aaaattggat tataaaaaag atttttttga ttatataata
    55021 ttgggagata tacttgaaca tttgattgat ccttggaaga tagtcaatga attgaaacaa
    55081 tatctaaaga aggatggtta tctggtatct agtataccaa atattatgca tgtttctgtt
    55141 ttaagaaatc ttgtgttagg taattttaca tatgaagatt caggaatttt ggacaagact
    55201 cacttaaggt tttttacatt aaatgagata acaaaaatgt ttaatgatag taattacata
    55261 ataaatagta ttacagctac tagtatgcca ctttcggaaa ttgataatag cttcattgat
    55321 acaatatgta aggaaagctg taaagaaatg agacaacagt acgaatctta tcaatatata
    55381 gtaaaagcct ctaaaatcct agatactaaa agatattcta gtattagtat ggttaattta
    55441 aaatacgctt taatgagaat tgataatgaa ttagatgtag atagtaattt aagttatata
    55501 tttgataatt ataatataac tgaaccatgt tttgttgatg atattgaata tctaattgat
    55561 acatttgtga taaataaagc aactctatta aatagattag gagttgaggc atttaacaga
    55621 ggtctaggag attttagtat aaacatgttt atgacagtat tagagatgga tagagatgat
    55681 attgactcaa tatataatat aacaagtgta ttatgtgaat tagaagaatt tgatactgct
    55741 tataatttaa ttaaaaatag tagcgaaaaa gtacagagtg aaagtgatat acaagagata
    55801 ttttgtttta ttgaggggaa gaaatatgaa taatgataag atatgtttta taacctgtgt
    55861 aaatgatgaa aggctttatg aagaatgtct tgtatatata aatagcctag acattcctaa
    55921 aaactttagt atagaaacag tagctttaag aggagccgat tctattgcct ctgcttataa
    55981 taaagctatg agagaaacag attctaagta taaggtatac ttacatcaag atacttttat
    56041 aattaataaa aatttcatac atgatatttt agagatattt aaaaaaaata cagatgtcgg
    56101 aatgattggt gtagctggag taaaagatat gcctgtgaat ggaatttggt gggattctga
    56161 taaaaaagca gggaaagtat atgatagtca tacaggtaaa atggatattt atgaatttag
    56221 taactttgaa gaatgtttta atgaagttat ggctatagat ggattaatta tgattactca
    56281 atatgatgta ttttggagag aggataagtt tgatgggtgg catttttatg atttgtcaca
    56341 gagtatggaa tttagacaaa ataaatacaa agttattgta ccaaaacaaa ataagccttg
    56401 gtgtatgcat gattctggag tagcaaatat aaataatgga tatgatgaat ataggataaa
    56461 atttgtaaaa gagtacataa atcttgattt atatagagaa aatttttatg aatttgataa
    56521 gaagaaagca agtgccatac ttaagagtaa taagcatgta atggattgta tgaaagagga
    56581 gcttacagaa caattaagat taaagaatta caaggatgtt ttaggtattg tttctaaaat
    56641 tgctcatttt tctgttttta atcatactgg tttgtattct tgtgaagaat gtgagagagc
    56701 attgctagaa tgtgcaaata atttaccaga aatagaaaat acgaaattat ttacaaaaaa
    56761 agatttaaaa agaagaaaag tattacatgt tttaagtgaa ggatattcaa caggaggtca
    56821 tacaagacta gttaaaaatt ggattgaaat tgacaaagac tctgttcatt cagttgtaac
    56881 cacatggcaa tcagatacac tgccagactg gttattaaaa gcaatagatg atagtggtgg
    56941 cgaagttata tctttggatt taatttcaga tgattattta aaaagagcta tggctttgag
    57001 aaaaatagct tatgactggg ctgatatagt tattttatat gttcatatgt gggatacaat
    57061 acctgttgtt gcttttggag ttgatgggaa aatacctatt ttacatgtta atcactatga
    57121 tagtactttt tggttaggga caagtattgc agatattgtc attgatttta gcgaagctag
    57181 tcaattaatt acattagata aaagaggcat agataaatct gaaatattac caatgccatt
    57241 aaaagaaaaa gaagtatttt caaaatctga agttagaaaa cgatataatt tggaggatga
    57301 tgtgacaata atattgacta ttgctagtga aagaaaatac aatagtgtaa atgatattaa
    57361 ttactttaaa attgctaaaa cattgattga aaatacagat aatacaatta ttattgttgt
    57421 aggagttgat acagagaatc tttattggaa aactttaagt aacgttacag ataatagagt
    57481 tatatgtttt ggaacaacag caaatataga cgatttttac aagatttcgg atatatatat
    57541 ggagtctttc atggtaggaa gtcatacttc aaaactagat gcaattttat atgatttaat
    57601 tcctgttaag tttaaaaatg aagtttcacc aatttttaca aatatgtgga attttataga
    57661 taagtttgat tataagaata taaaagaggt tatagatatg ataaaaaggt acaatactag
    57721 tgaatttgac agggataaga taaaagaaaa acaatcggaa ataaaacatt ttgttataga
    57781 taaacactgt attgaaataa aaaactatat agacaaaata tataatgaag ctaatcatca
    57841 taaagttaag tataatttat ataaaaatga tgaaatcgag gactatcagc tttttgtagc
    57901 attatatggc tatatggtaa aaaataaaaa catgtcatag gtggtaaaat gaacaatatt
    57961 catatcaata aatttgaaaa aagctgtgaa aaaaactggg attattttgt agaaaataaa
    58021 tctataaatg gtacatttct gcaaactaga aatttcctta attatcatga ggagggaaaa
    58081 ttcactgacc actcattaat aatatgtaaa ggtgaagaaa tactagcagt cgtacctgca
    58141 tgtgaaactt atgaagatgg tgaaagaata tttttttctc atttagggag tacttttggt
    58201 ggtattataa taagaagtgg ttttaatgat attaggcatg taaattccat tacaaataag
    58261 ttagaaatat atttacggga acaaaatttc gataaagtat atttaaaaaa tacatcaaga
    58321 atattttgta aagaggatac ttcattacta gaatattttt tatttaagaa taattacatg
    58381 ttttatgatg aattaagtat gtttttagaa ttaagtaagt ataaagaaga tatattagcc
    58441 aattttaaat acagtaaaag aagagatttt aaatattctt tgaagaataa tcttaccttt
    58501 aaaagactgt atagtgatga agatatagtt tgttttttta atttactttc taattgttta
    58561 gatagtaaag gagctaaagt aatacattca gtagaagaac ttttggagtt taaaaataat
    58621 agattaaaag atattgtaga attttatgca gtatatattg atgacattat gatttgtggg
    58681 agcatggtat ttaactttca agaaagagtt tatcatactc aatatctagc atcaaattcg
    58741 acatataata aatattatcc aatgatattt ttatactata atctaataaa agatgcttta
    58801 gagagaaatt ttaagtatct ttcttttgga attagcactc taaatagagg caaatactta
    58861 gacgagggtt tagctacatt taaagaaggt tttggttcaa gtgcaatttg taacagaaca
    58921 tactataaaa atataaataa gtgagaatca tgttttatag agtttttaga gtatagtaaa
    58981 tatctagtac tctaatatta cataaaaata attagtttat aaagaaggtt tgtatatgaa
    59041 aagattaatg attttaggct caattaagta ttttgagaat attgttatat cagctaaaaa
    59101 agagggaata tatacaattg tttgtgataa tagaattgat actcctgcga aaaagatttg
    59161 tgatgaagca atagatgttg atgtatttga ttttgataaa ataaaaagta tagctataga
    59221 taaaaagata gatggaattt taactggatt tacagattct ttaatgaaac catatgttta
    59281 tattgcaaat gaactaaatt taccatgtgt gatttcttgc aatcaacttg aatctgtaac
    59341 taacaaggct attatgaaaa aatattttaa aaataatgca atacctacaa ctgattattg
    59401 tattattgaa agtctaaaag atttagaaaa aatacaaaga ttaaattttc cacttgtaat
    59461 aaaacctgtt gatggttatg gttcaagagg tgtatatttt gtatcaaata tagaagaatt
    59521 aatagaaaaa tttgaatatt ctaaggaagc ctcacaagat ggacaagtaa taattgagga
    59581 attttatgaa agtgaggaaa tacaagggct agcttgggtt cataatggag agtcacatgt
    59641 attttatatt ggagatagag agcttgtaaa catacataca ggaagagctg gaaaaccaga
    59701 tagattactt tatccatcaa agtattgttt tcaatatgag gaggaaataa aatctatata
    59761 tcaaaatata acacaggctt ttgatataaa aaatggacct ctttatgtac aaatgttagt
    59821 gggagcatat ggaataaagg tatctgaagt aatgccaaga ttacctggag gttgtgacta
    59881 tatggctatt tctcaaataa cagatttaga cataggaagt ttatttgcaa actttagtgt
    59941 gaataatgaa gtaaattttg atgaaataaa gaaatataat atgcatctat caaaatgtgt
    60001 atatgcatta ccaatataca taagacctgg gacaataaaa aagataaata atatagataa
    60061 aatagaaaac ttagattatg tcactcaatt tctattacta gtaaaagaag gagatacaat
    60121 agaattatat gaagatgaga gacaggattg tggaagagtt tatggaatag caaataatat
    60181 atttgatgca aatataaaaa agaaatgtat tcatgaaatg atagaaatac ttgatgaaaa
    60241 taatgaaaat atgatagaaa atttttaaat aagggagtat gatagatatg aagttaataa
    60301 ctcatgaaca aattatgtca ttaaacattt ctcagaaaca aggatatgag tggataaaag
    60361 aatccttctt aacaaaaaaa gattgtcaat taccaccaaa aataagcatg gtagaagaag
    60421 gacatgtatt ttacaatgta atgccatccc taaatcataa tcatatgatt ggtggaataa
    60481 aaatggttac aagattgcca gggagaaatc caagtttaaa ctcagagata tttctatata
    60541 atatggaaga tgctaaatta aaggctattt tggatggtaa ttatattaca gcttttagga
    60601 ctgctgctgt tgctgccttg gctatcgata catttgctaa aaaagatttt aatactattg
    60661 ctattatggg tttaggtgtc actgcttctg ctataatgaa tatgctttca tatactctta
    60721 aagataaaaa tataaatata aagttactta aatataaaga ccaagcagag tcgtttgtaa
    60781 aaaagtatga aaaaaatgaa caatttagtt ttgaaatatg tgatacacat gaagaactta
    60841 ttgtagattc agatgtagtt atttctactg tgacatatac agatgaatat ttatcagaat
    60901 ttaaatggtt taaaaaaggt gctttattat tacctgtaca tgttatggga tttggaaatg
    60961 ttgattatct atttgataaa gtatatttag atgattataa tcatttgaaa catctagaaa
    61021 atatagatag atataaatat tcttgtgaat tttatgatgt tttaagtaaa caagctaaag
    61081 gaagagaaaa tgatgatgag agaataatat cttacaatat aggtttgtca atacatgata
    61141 tattatttgc aaataaaatt tacgaattgt gtgaaacact aagctgtgaa gaaatagaat
    61201 taaaagaacc aaaagaaaaa tattggatat agtttatttc attcatattt acaatagttt
    61261 attgtaaata tgaatatgaa gtaatatatt gttagaaaat tagcatgaat aggatagata
    61321 aatttatgga taaatataat ttaattaggt tcgtatctat tggaaacgaa tatataggaa
    61381 atttagttgc attagaatca aataaagtaa taccttttga tataaagaga gtttattaca
    61441 tatatgatgt accaaacaat gtaaagagag gatttcatgc acacaaaaac ttggaacaag
    61501 tactagtttg cctaaatgga agtgtgaaga taaaatgtta tgatggtgta aaagagacta
    61561 tatttaattt acataaaaat gatgttggat tatatatagg aacgggagtg tggcatgaga
    61621 tgtttgattt tgatgaaaaa actgttttaa tttctatagc atctgaacat tataatgaag
    61681 aagattatat tagagactat aaagaatttt taaagtattt aaataatatg tagttattat
    61741 acaattagtg atgtattttc ttaattaaat aaatttaaga tagccacata gagaatagat
    61801 agattaggat gtgaatttat tgttggttaa atttaataat ttattaaaac agttccaaac
    61861 tcataaagaa gaatatgaac agaagattaa ggatgtaatg gaaagtggat attatatcct
    61921 tggaaatgaa gtaaagcatt ttgaagaaga atttgctaac tatgtaggta gcaaatattg
    61981 tgttggttta gccagtggtt tagatgcact gataattgct tttagagcat taggaataag
    62041 caaaggtgat gaagtaatcg tgcaatcaaa tacatatatt gctagtgtta tgggaatcag
    62101 tataaatgga gcaacaccag tatttgtaga accaaatgaa tattataata tagattcatc
    62161 taagatagaa gaaaagataa atagcaaaac aaaagctata ttagtagtgc atttatatgg
    62221 tcaagcaagt aatatgaaag atatacaaga attatgtgat aagtataact tgtatttaat
    62281 tgaagattgt gctcaatctc atggagctaa atatgatgga aaaatgacag gaacatttgg
    62341 tgatataggt tgttttagtt tttatccaag taaaaatttg ggtgcatttg gagatgcagg
    62401 agctatagta actagtaatg aggaaatagc tgataaagtg aaaattctta gaaactatgg
    62461 ctcagaaaag cgatattata ataaatttgt cggatataat tcaagattgg acgaaattca
    62521 ggcaggttta ttaagagtaa aacttaaata tctaaatgaa attgaaattg aaaaatcaaa
    62581 aatcgtagat agatatctta atgaaattaa taatcccaaa gtcatacttc caaagataga
    62641 aaataattgt actcatgtat ggcatttatt tgttttacaa gttgaaaaac gagatacatt
    62701 tatggaatac ttaaagaaaa atggtataga gtctataata cattatccga taccaccaca
    62761 tctatctgaa gcatatgctt atttgggata taaaaagggg agttttaata tagctgagaa
    62821 ctattcagat aaagttgtta gtataccttt atttatcggt atggaagatg aagaagttag
    62881 ttatataatt aaaattataa atgaatatta aactactcat aataatatca aaaataaatt
    62941 ttttatatat catttattta aatttcgtta attgacattt ttaaatattg atatattgta
    63001 caaataaaat tgaaatatat ggaaaaatat agaattaaga tgagatttgt cttatatttt
    63061 tataaattaa aaatattttc aaagagttta
//
LOCUS       DAEPXW010000008        61098 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.008, whole genome shotgun sequence.
ACCESSION   DAEPXW010000008 DAEPXW010000000
VERSION     DAEPXW010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61098
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.008"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            212..1540
                     /locus_tag="KRM55_000503"
     CDS             212..1540
                     /locus_tag="KRM55_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1592774.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2293..3126
                     /locus_tag="KRM55_000504"
     CDS             2293..3126
                     /locus_tag="KRM55_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH1592775.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3219..4151
                     /locus_tag="KRM55_000505"
     CDS             3219..4151
                     /locus_tag="KRM55_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1592776.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4203..4685
                     /locus_tag="KRM55_000506"
     CDS             4203..4685
                     /locus_tag="KRM55_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1592777.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            4697..5566
                     /locus_tag="KRM55_000507"
     CDS             4697..5566
                     /locus_tag="KRM55_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH1592778.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5609..6364
                     /locus_tag="KRM55_000508"
     CDS             5609..6364
                     /locus_tag="KRM55_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH1592779.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNTKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KEDNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6406..7227
                     /locus_tag="KRM55_000509"
     CDS             6406..7227
                     /locus_tag="KRM55_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HBH1592780.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7232..7993
                     /locus_tag="KRM55_000510"
     CDS             7232..7993
                     /locus_tag="KRM55_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBH1592781.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTVQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8154..8411
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8524..8763
                     /locus_tag="KRM55_000511"
     CDS             8524..8763
                     /locus_tag="KRM55_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH1592782.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9067..10062
                     /gene="ilvC"
                     /locus_tag="KRM55_000512"
     CDS             9067..10062
                     /gene="ilvC"
                     /locus_tag="KRM55_000512"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBH1592783.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VMIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            10115..11803
                     /gene="ilvB"
                     /locus_tag="KRM55_000513"
     CDS             10115..11803
                     /gene="ilvB"
                     /locus_tag="KRM55_000513"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBH1592784.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSIEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            complement(12164..13294)
                     /locus_tag="KRM55_000514"
     CDS             complement(12164..13294)
                     /locus_tag="KRM55_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1592785.1"
                     /translation="MKGGVRKRSNKWYYYFDLGIVEGKRKKVERVGGNTKKEAEKALR
                     EALNEYENSGIVFEESNISLSDYLDFWYKEYVLLNCKYNTQESYRINIEKHIKPKLGA
                     YKVKALTPAILQNFINKKYKEDYSQNTLQVLKAILHRSLKSAVHPYKHIRENPMQYVS
                     IPKTKSKTETNKVKTITLEEFNQILNIFPQDSFQRIVLLIGFHTGMRRGEIIALKWNN
                     IDLDNKTITVKHTLIKKPNGMFELGQPKTESSCRTIFTGDTLIKALKEHKLYQKKMKL
                     KYGEFYFDSDWVCTKENGQQVNTHTLDTIVRQIRVALNNDFHFHSLRHAHATLLLENG
                     ANIKDIQNRLGHSQLSTTMDTYSHVTDKMKNETVDIFEKITN"
     gene            complement(13535..14041)
                     /locus_tag="KRM55_000515"
     CDS             complement(13535..14041)
                     /locus_tag="KRM55_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBH1592786.1"
                     /translation="MNKLDALLDLANNEEIEIYYTDKIADDIKGLYINRQGLKIISLL
                     NSLKQNNAKLIEILAEELGHHFTSVGNYVSSKNSYKNKILIDKTENKALKWACEFLIT
                     EEEIIHVINSHATSVYEIAEELQVSINFLLKRLEFLSKKKSMLDLGNNRFLVLTNLPN
                     FYIYEDIF"
     gene            complement(14145..14567)
                     /locus_tag="KRM55_000516"
     CDS             complement(14145..14567)
                     /locus_tag="KRM55_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBH1592787.1"
                     /translation="MPKLYDYRVFISHAWKYGNDYDRLINLLNNANNFSYYNYSAPKE
                     KPLFPDGTPFSNSDIAKKITDKISPSQITIVISGMYVQYKDWIKYEIDESIRIGKPIL
                     GIRPYGNSNIPTYVSDNANKIVNWNTDSIVSAIRELVK"
     gene            14631..14852
                     /locus_tag="KRM55_000517"
     CDS             14631..14852
                     /locus_tag="KRM55_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012102221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592788.1"
                     /translation="MQVKKFRKKPVVIEAYQTDIEFIIQTLEGPLKASIGDWIITGVR
                     GEQYPCKPDIFEKTYEAVDDEVPLTSFIV"
     gene            complement(14865..15281)
                     /locus_tag="KRM55_000518"
     CDS             complement(14865..15281)
                     /locus_tag="KRM55_000518"
                     /inference="COORDINATES: protein motif:HMM:NF033634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBH1592789.1"
                     /translation="MSEEQYLENRVNKQINWYSSKSSNIKKKFFTIQVIEIIIAGIIT
                     ALSKFSFENEHIADIITILSIVVIIFSSLRNLFKWQDLWIKYRYTAELLKREKFLFLT
                     RTNIYINENAFNLFTERIEDILNRENENWTELNLNS"
     gene            complement(15290..15835)
                     /locus_tag="KRM55_000519"
     CDS             complement(15290..15835)
                     /locus_tag="KRM55_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1592790.1"
                     /translation="MFRLKELREEKGISLDRLSMDLNVNKSTLSRIENGLREPKQSFI
                     EDCSNYFDVSTDYLLGKTDIKNPNQVVKSLNPIFSKRLRELIKEKGVTLNILGKKLEI
                     STDLLSKYENNIISPKSDDIIKLAHYFDVTTDYLLGTTLVRNHIDTVAAHKANPHEDL
                     PEEAQEQLNDYIEFLMNKYKK"
     gene            16016..16231
                     /locus_tag="KRM55_000520"
     CDS             16016..16231
                     /locus_tag="KRM55_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1592791.1"
                     /translation="MYVNRLKGLMKENQHTQKFVADLLGLSLFGFRLKLNGKNEFKAN
                     EIKKLSELYGVSTDYFFSESVAKMAIK"
     gene            16262..17080
                     /locus_tag="KRM55_000521"
     CDS             16262..17080
                     /locus_tag="KRM55_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein/antirepressor Ant"
                     /protein_id="HBH1592792.1"
                     /translation="MKDLKIVKVNNKLTTDSRDIALMVEKEHKILLRDIRNYINQMEE
                     ANKNMSTDLYPSDYFIENTYFDDYKREKPCYAITKIGCDFIANKMTGIKGTAFTGIYT
                     KKFDEMEKYLKNEPQPKLPTTYKEALQHLIEQVEVNEKLQLEGKMKDQVIKELKPKAD
                     YTDMILKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQYQGKGYTH
                     SETIDITRSDGMTDVKMTTKWTQKGRLFLYDLLKVNNILPDIEKEYSYQTSMLG"
     gene            17129..17266
                     /locus_tag="KRM55_000522"
     CDS             17129..17266
                     /locus_tag="KRM55_000522"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592793.1"
                     /translation="MSNRKKYTLSITKELYNKCKEKANQRGMSVNEYILSVISRNLEN
                     V"
     gene            complement(17278..17445)
                     /locus_tag="KRM55_000523"
     CDS             complement(17278..17445)
                     /locus_tag="KRM55_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HBH1592794.1"
                     /translation="MPSKLPRYTLRIDNNLLEKIKYIAESEGRSANKEIEQLIKKHVE
                     NYEKINGKINV"
     gene            17568..17744
                     /locus_tag="KRM55_000524"
     CDS             17568..17744
                     /locus_tag="KRM55_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system HicB family antitoxin"
                     /protein_id="HBH1592795.1"
                     /translation="MTAKKRVTVRIPDELNEELHRQSQRKGLSKNAFIINILWKEFED
                     LQDLKNEQEVDKYE"
     gene            17737..18540
                     /locus_tag="KRM55_000525"
     CDS             17737..18540
                     /locus_tag="KRM55_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBH1592796.1"
                     /translation="MNNLTIIKQNNKYLVESREVAELIEKDHNQLLRSIRGYISVLEQ
                     SAKLHTDDFFIESTYKNENNQKYPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFDE
                     MEKSLRNEPQPKLPTTYKEALQHLIEQVEVNEKLQLEGKMKDQVIKELKPKADYTDMI
                     LKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQYQGKGYTHSETID
                     ITRSDGMTDVKMTTKWTQKGRLFLYDLLKTNNILPDIEKEYSYQTSMLG"
     gene            18588..18770
                     /locus_tag="KRM55_000526"
     CDS             18588..18770
                     /locus_tag="KRM55_000526"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592797.1"
                     /translation="MNEKDTKITEKDLHYITDYLLKESDIGKRLALLEEKTKPIKIDE
                     ISDYLSKRISDKTSLT"
     gene            complement(18728..18964)
                     /locus_tag="KRM55_000527"
     CDS             complement(18728..18964)
                     /locus_tag="KRM55_000527"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592798.1"
                     /translation="MNKDELNKICDEVYNRILKSEYSDETLLRNKISEFISLKEKSTS
                     EISNTELCMFFYFENIAFTKNYVKEVLSEILLDK"
     gene            19134..19526
                     /locus_tag="KRM55_000528"
     CDS             19134..19526
                     /locus_tag="KRM55_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1592799.1"
                     /translation="MDISESIAKQFSDSLKSLIEIEINKQETDRVKSQTVEQKVKVLE
                     PKDIVVLIKRGYPNYLITVEEARGILKLDTVFMRRLVSTGLIKSLARGDGRKISRYEV
                     DDFIERNQGKNLDELLKAAERGDEIVKP"
     gene            19513..19656
                     /locus_tag="KRM55_000529"
     CDS             19513..19656
                     /locus_tag="KRM55_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592800.1"
                     /translation="MLSLNTNKNNIVTLKKDGKVIADIVFKDIKTGKKISVGVLNKKV
                     LVK"
     gene            19823..20065
                     /locus_tag="KRM55_000530"
     CDS             19823..20065
                     /locus_tag="KRM55_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592801.1"
                     /translation="MEAARLIAIGQIKQAEKEICKLQGTKNNSSLMWWEAVKFASQNI
                     LEGLEHDIELEASIEFREAMMYQEELEKDRPIDVQI"
     gene            20144..20425
                     /locus_tag="KRM55_000531"
     CDS             20144..20425
                     /locus_tag="KRM55_000531"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592802.1"
                     /translation="MKTKNEIIKDLEDRLFLLRFTTVDEVDWDVKFGQISALEFCIDK
                     HRKGCTLQQFKENLEEYKLQGNYGDYIDGFVSVLERNIREMEGEIDGSE"
     gene            20412..21050
                     /locus_tag="KRM55_000532"
     CDS             20412..21050
                     /locus_tag="KRM55_000532"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBH1592803.1"
                     /translation="MEVNNIYIKLMDVRIKFNKLDIKKSGQNKFANFKYFELADFLPQ
                     ATELLQEAKLCPIVTFTNDYATLTLINGEKPTEEIIFTSPMRELQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITENDTFDATSGKEDYKRNDLTNSSIKASENGQIKISQNQIKRL
                     FSIGNTIGKDSDRVKSEVYYKFNKEVKDLSKQEYDQICVGYEKLQREKGIIK"
     gene            21069..21959
                     /locus_tag="KRM55_000533"
     CDS             21069..21959
                     /locus_tag="KRM55_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH1592804.1"
                     /translation="MDKVIIEKGNILSDGYGLMPRLVARDRWLTVGARMLYSYLSSFA
                     GINGTCFPTRDLICYELNISKDTFTKYKNELELSGYIKIHKNKSKQGKMQNNIYEIVF
                     DRTYIDECISRRGVKVNKKKKKPCPKNIDMEPCPTFPDTTQPDTENVDTNINSFNINS
                     FNSMYIDKPVDNYLKEFKKLYEENIGVVYPVTAEWLLEVSKEVDIRVFKRAIEICAER
                     MNMNLSYLKGILKKWKDANITTYEQLESYKLQHENKKSKKPNSVVSKNKFANFEQTFT
                     QYSNKELDEIIKKSQKAKFK"
     gene            21979..22398
                     /locus_tag="KRM55_000534"
     CDS             21979..22398
                     /locus_tag="KRM55_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1592805.1"
                     /translation="MNQVVLVGRLTRDPELKYIPGTGTAVASFTIAVDRNYINKEGKR
                     DTDFIPIEVIGKSAEYCANYITKGKLVALEGNIRVDNYQTQSGEKRTFTKVSTKSVQS
                     LESKSKSSNSYKESVQDGTIGLDPQGFEIIDDDELPF"
     gene            22428..22790
                     /locus_tag="KRM55_000535"
     CDS             22428..22790
                     /locus_tag="KRM55_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592806.1"
                     /translation="MFKVERYFSGSVVDNLIEDDLTCRNYLALYCCLLGITKNGKKIY
                     PKPEKMLAEFGVKKDRKIKKELPVRIRNVNTGEVKEFESMDGAACFLRLKYQAVYQAI
                     KKKTKTRSGWKVEYIKEE"
     gene            23203..23400
                     /locus_tag="KRM55_000536"
     CDS             23203..23400
                     /locus_tag="KRM55_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592807.1"
                     /translation="MNKFQKAVSQMVKQEEKENLWQGYENCRVGRSISSSIRRYVKGF
                     KKFGYSVHEVYEFINDINKYE"
     gene            23427..23843
                     /locus_tag="KRM55_000537"
     CDS             23427..23843
                     /locus_tag="KRM55_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015615683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBH1592808.1"
                     /translation="MSKYNNKKIVIDGIKFDSKDESEYYLYLKEKKENGEIKDFGLQQ
                     KFELQPKFKKDGKSYRAITYTVDFAIYKWNGEVVYIDVKGYSTQQGELRKKLFDYKYQ
                     DKKLIWIAKSKKYGVDGWIEYSELKKKRKENKKKVA"
     gene            23862..24362
                     /locus_tag="KRM55_000538"
     CDS             23862..24362
                     /locus_tag="KRM55_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592809.1"
                     /translation="MASKVKKEFFMATKKHLENYKQLHINIESLKLQIKNLKEFHLGD
                     FMQGLSYDSIPISKTNSISNQVENELINLEEKIIEKQIELYEMEALKYTIDVSISNLK
                     PIHKQIIRYRYIEGLEWSLIVDKVYLEERQLRERANQAISSISIALFGKKALIEQEPL
                     FKMLDL"
     gene            24772..24948
                     /locus_tag="KRM55_000539"
     CDS             24772..24948
                     /locus_tag="KRM55_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBH1592810.1"
                     /translation="MEKRILKVLLSKSGSGSLSPKISLPATWIKEMNITQEEREVEVY
                     FENNEIRIKKKDLD"
     gene            25374..25814
                     /locus_tag="KRM55_000540"
     CDS             25374..25814
                     /locus_tag="KRM55_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013725420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBH1592811.1"
                     /translation="MADLTEKQKRFCDYYIETGNATEAYKKAYKNNNQRTSESNGSRL
                     LSNDKVKNYIDERLKQIESKRIADAKEVMEYLTKILRNQEQEEVVIVSENGPEIIKKD
                     VSIKDRNKAAELLGKRYALWTEKVDLDGNVGVTIIDDVGNLNDG"
     gene            25804..27069
                     /locus_tag="KRM55_000541"
     CDS             25804..27069
                     /locus_tag="KRM55_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007780425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBH1592812.1"
                     /translation="MMDRKISEIINKNFYEFWKVSNSNKYLYHVLKGGRASAKSTHIA
                     FWLTMAMVKYPVNTVCFRKVGNTIMDSVYEQLKETIEIFGLTHLFQFKKSPMEIIFIP
                     RGNKFIFRGLDDPQKIKSIKSAKYPIAFAWFEEVAEIKTEDELSMVINSVLRGELPDK
                     LNYKIFLSYNPPKRKQSWVNKKFETHVLPKNTYVHHSIYLDNPHISKAFIEEANEIKI
                     RNEFKYRWEYLGEPIGSGVVPFSNLEFKTITNEEIFQFDNIRQGNDFGYATDPMAFVR
                     LHYDKKKRVIYFIDEIFGVKMSIRELASKIKSKGYDDFSVICDSAEPRSIAELREYGI
                     KALKAKKGPGSIEFGENWLDDLQAIVIDPNRTPNIAREFENIDYQTDKDGNVRAKLED
                     KDNHSIDATRYALELDMKTHGRERKYNSR"
     gene            27080..28564
                     /locus_tag="KRM55_000542"
     CDS             27080..28564
                     /locus_tag="KRM55_000542"
                     /inference="COORDINATES: protein motif:HMM:NF016988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH1592813.1"
                     /translation="MLDLIDIIQMELTGLYGQEVIREMGEIIRLYDKYEGTGQHWIEE
                     EQDYKQTRKKTNYIKKLIKEEARFLFGKTPIFTIKPENDLDKDKAEEINQCINKILKK
                     NLFSDKLIKAARDCFIGKRIAIKLHADKESKSLKIMFVPSLEFIYEPFDNQFDELKKI
                     VFFHQTNQEVEKDKQRIWKQKYEMVNGKCILSEGIYNGYGLCIEEIVSDTDLKLSGIP
                     CYVILNDGLLGDLKGESDIEEIFDNQMAYNKLASEDIDTLKKGMNRIIYGVDVEEESS
                     KHFKIKPGAYWDVETSQTADQKQAQINTIPTDFGYDTRIENSLNRIKSDMHEVLNIPL
                     INNQDLKGMMTSGKSMKALYWQLITRCEEKMKSWGPALEWLIQAMIEMIEVYNIVKIP
                     ILDKDSYEVIVENQYPLQEDEDSEKLLDIQQVNAQAMSRKTFIKKWNNSNDDIADEEL
                     QQISIERQILEESFNLEEETEAIDTEESDEVTNEKESKEVVDDE"
     gene            28564..29982
                     /locus_tag="KRM55_000543"
     CDS             28564..29982
                     /locus_tag="KRM55_000543"
                     /inference="COORDINATES: protein motif:HMM:NF015461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592814.1"
                     /translation="MANKFNKAMKNAERARDILSNRTTKKIRKLYKDIANEYAKKLNR
                     VNSNTLTEQYLRESIIYLNKEYDRLGKKLKKDIESEISKVIKTTTDEQLSFFNNICDN
                     YSVNLKPQFTDMFSKVHEDVLRQVISGSMYKDKLKLSDRIWSNIDKTKKDLDYIVSRG
                     LAEKRGSYDIAKDLEKYVNPKVKKDYDWSKVYPKSNKKIDFNAYRLASTYITHAYQKT
                     AKESCKKNPFVKGIKWMSSHHPRMCKVCADRNGKTYIPEELPLEHPLGKCTFEYDIPM
                     SMEDIGKELRSWIDGEENSKLDEWFDEYGLDFAGIEGKANKNKEPTEDEMLALYKYMG
                     GDAYKINEKLRRNIKLTEEDEWFINNLDRVLDKMPNYEGDVTRSLYFYNKESLKAFLI
                     EHEIGKTIQYSEFISTTKGKTYNPEGQVEIYIFNSKNGKNISMYNEKEEEVLYRRNSK
                     FEIIELEEMNGKYYILMEERNG"
     gene            29975..30151
                     /locus_tag="KRM55_000544"
     CDS             29975..30151
                     /locus_tag="KRM55_000544"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592815.1"
                     /translation="MDNKFEDDKYSEPFSHPRWKDVPWGETIGYRDIPEEERKKYKKI
                     LREHLKDIGVLKED"
     gene            30183..30422
                     /locus_tag="KRM55_000545"
     CDS             30183..30422
                     /locus_tag="KRM55_000545"
                     /inference="COORDINATES: protein motif:HMM:NF015461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592816.1"
                     /translation="MYKLGEIVTNYDYTSTTKGSTYNSEGQVQMYILNSQKGKDVSKY
                     NPKEQEVLYKRGSMFKVIEIERIKGTIHILLEEVY"
     gene            30423..30638
                     /locus_tag="KRM55_000546"
     CDS             30423..30638
                     /locus_tag="KRM55_000546"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592817.1"
                     /translation="MLTIEEFIKLPDEEKGDAYKELSPHDMFLWRTQYSPIGFEVIGH
                     EEISEEDRIKNKKKFREHLKKIGVMEE"
     gene            30668..30844
                     /locus_tag="KRM55_000547"
     CDS             30668..30844
                     /locus_tag="KRM55_000547"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592818.1"
                     /translation="MCNKFEDDKYLEPFSHPRWKDIPWGETIREVERTEEEQAQIRTK
                     FRKKLKEIGVIKED"
     gene            30980..31615
                     /locus_tag="KRM55_000548"
     CDS             30980..31615
                     /locus_tag="KRM55_000548"
                     /inference="COORDINATES: protein motif:HMM:NF018515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBH1592819.1"
                     /translation="MEELLKKLGYQDTDIKNIIEGMKKDKIYTSKEENIDERYNKLKE
                     QKLALEEQIKGANDTISDLKKNSKNSEDIEAKVKEWENKYNELDSTSRAKIKNMTIDY
                     AINSKLSGVNEKYRKLLCKEFDTSKMEVKDTGEIIGLDEQFKDISETYKEWFESSTPS
                     NTGSPGNFPRKSNVVNNPFIKETFNLTEQGRLLKENPDKAKEFAAQAGINL"
     gene            31633..32601
                     /locus_tag="KRM55_000549"
     CDS             31633..32601
                     /locus_tag="KRM55_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006774096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coat protein"
                     /protein_id="HBH1592820.1"
                     /translation="MAVTKLSDVIVPELFNPYVINKSMELSALYQSGIITNDASLNAL
                     ASQAAPVVNMPFFEDLSGESEQIIEDADLTPNKITSSQDAAAILRRAKMWAATDLSAA
                     MAGKDPMAAIASLVGSFWARDMQKELIAVLNGVFLAANMTTNKLDISAGTGNAAKWSP
                     SAFIDAQQLLGDAQGQLKAIAMHSATKSALKKQNLIETIRPDVGPDFEVYQDKLVIVD
                     DGCPVSKEGVYTSYLFGSGAIALGNGNPVGFVATEIDRDKKKGSGVDYLINRKTYILH
                     PRGIKFTNASVAKTEGPSRLELAKGENWTRVYEPKQIRIVEFKHKL"
     gene            32627..32881
                     /locus_tag="KRM55_000550"
     CDS             32627..32881
                     /locus_tag="KRM55_000550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592821.1"
                     /translation="MDLEILKNIKTELREEQSPFFSDDEITYYYNKNNQDFNKTMYEL
                     CILKAENDSITLPGGLSMPENKLYWLTLAKKFKTNGSRCL"
     gene            32878..33240
                     /locus_tag="KRM55_000551"
     CDS             32878..33240
                     /locus_tag="KRM55_000551"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592822.1"
                     /translation="MIAQKVKPKIIKAINKMPTEAIVKRVGVNEFGEPSDEENIVCNV
                     IGLYHEGSSSISQITKDKGIVIKDKEQYLMVVCDEDTVKIKQGDFMYLDNNKFIIQDL
                     GNQNRMNIYFDLKLGKVR"
     gene            33242..33676
                     /locus_tag="KRM55_000552"
     CDS             33242..33676
                     /locus_tag="KRM55_000552"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592823.1"
                     /translation="MSKGFKFDTSKLLNALVSREMKTKAALGAYADTSSQLLESTAKN
                     DRPWKDHTHDAKNRLHGSWEWQGDTIRIALSHGVDYGLYLEKGTGPHVIEARPGSYLF
                     WDGASHSVKKVNHPGSRPYPIIMPTIEKCAPSIIRGLDVILK"
     gene            33684..34028
                     /locus_tag="KRM55_000553"
     CDS             33684..34028
                     /locus_tag="KRM55_000553"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592824.1"
                     /translation="MFKKIYKHLKNKGFNVYSIGQHQGLCIEPFLVIFEKGPLQTTEK
                     NIIKDLFEIYVFYPIGQYSKVSEYKISVESVMDEIVGIKQAYEALPILIDDEKQAYFT
                     RLSYYENKQIRR"
     gene            34034..34840
                     /locus_tag="KRM55_000554"
     CDS             34034..34840
                     /locus_tag="KRM55_000554"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592825.1"
                     /translation="MAVQILNQYPLTDVVLVQIETVEQNPVTYTFDTSDEIGTEEIIS
                     EGEELTLKIKKKIIANRAAEDTSLGYDLTLKDNVFCPEILQIMQGGTIEKEEDGSFKR
                     YLAPEVGKTFSKKSFKTIIYSSVVGPGGDTGQFAKTTFPNCKGKSVPLNFKDGEYYSN
                     EYVINSRPNTGQSPYEVEIVEELPNGYEATKVFLDSASVSGATAGDKKITGLTAGKIY
                     KVTVNSNIKYTLADGTLTDTESDKAALTGTEIIGLTNGETYKVEEVSISI"
     gene            34899..35375
                     /locus_tag="KRM55_000555"
     CDS             34899..35375
                     /locus_tag="KRM55_000555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592826.1"
                     /translation="MNELKVTSLEELKKIKLTEVIEVGRFLDGTMLVAEVKQPDLMAL
                     AMAGKIPNSLMTASMSLVEEKESKDSTGEKVLKKMNDESNFSKEMFEMMDIVAKEVLV
                     NPTYAQIKKIGLELSIEQRLTLFNRIQGGTKSLENFHQESTDIEDSKSSDNIQQDA"
     gene            35368..35565
                     /locus_tag="KRM55_000556"
     CDS             35368..35565
                     /locus_tag="KRM55_000556"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592827.1"
                     /translation="MPSEILRIKDEYTSFCFDEACMFLVDAIKNDKKLKFENNEKKTI
                     DKNERKTFVQIALEKKKKVNR"
     gene            36115..36486
                     /locus_tag="KRM55_000557"
     CDS             36115..36486
                     /locus_tag="KRM55_000557"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592828.1"
                     /translation="MSLFGSKITKEEKEKNREETEKHYERLKNMTKEEKKEYEIQEFM
                     KKYQLENLDEKDLIVLKRIASDLFGNGLIKAGMALSFTDAKEQAKIGYLSALTEQNWM
                     IIRQLAQLNTNIEKLIEDKKE"
     gene            36566..42316
                     /locus_tag="KRM55_000558"
     CDS             36566..42316
                     /locus_tag="KRM55_000558"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBH1592829.1"
                     /translation="MSLELGTAVGYLDLDGGKFFKALADAAKQLSQFNSHTKSTGSAM
                     TAMGKQISDTASSLTQIGRQSALAASELNKIASTSSGPFSSLKNSIKQTENELKTARS
                     TIDAYAQGISKLTSEIDKSKQKYTEIGSKIERYEQQLERCNSMYGESSEQSQRYREAI
                     ERLKNSQTQLGNEIENGEDSLTDMRTAMNNAEAEANRLSDSLSSMPFDAIGGKMRDIG
                     QTLTSIVTTGLVAMGTAAVTAATSTEQAMSVVNSILQLNTEKVQGGKSEWDAYASTLK
                     EGANEIGMAYDEYANSAYNAISASVKQADVTEFLAQADKLATAGLTDLAKATDVLTTI
                     QNAYGMSQKDMAHVSDVLIQVQNKGKITVDELANSMGKIIPTAKSLNVSVEQLGAGYA
                     ILTAKGIAGAEATTYMNAMLNELGKSGSKADKILKKLTDKGFADLQKEGKSTADVLLI
                     LNDYAKKNSLSLSDLFGSAEGAKAANVLLGDAVNETTGEIIEGTKSADSFNQMLNDMK
                     NSTGLCDKAFEQLDNTTKTKLEDALNSAKNMLSDLGEVMMPVVAKVAEMATAFMKSVS
                     EMAKSNPNFARIIVSIGAVVAAIGPLLVVLGTMAITIPKAISAIGTAGKAFTFLSTSF
                     AIARKTITSTSAGASAGMIKMSKVMAGLMGPMGLVVAGIVALGVAFVALNKHMSQDSI
                     QVSERFGKNISDGTQKAVGAFMDLEEQTTTTLNQMLWSGETVSTEMKDTLISNFDSMS
                     SQITSKLNETKESSQATLQEMFASSTTLSDKEKEALIKNTDEAYSNKEKKVEESTARV
                     KEILTKASEENRSLTQSEADEINRIKTEMLNTAVNVMSESEAEQAAIMERMRANATNL
                     SAKQAADVVKNSIKQRDETVKSANEEYNERLKLAAQLRAEGGKENEELANKVIQEATK
                     QKDEAVKKAQEMHKEIVSEAQKQAEGQVEKIDWTTGEIKSRWEVLRDEIKKNIDTSQS
                     DFDTWCSNTDKGFADTWNKITQGVSNAWNGITESLSNAWNSIKEGCNNLWASISEGVS
                     NAWNSILEWTTTIWSNITSFLGELWESIKEMAINAWNGIVSSVTDAWNSITEFLSPVT
                     SFISEMVKMAWESIKETAITIWQSISDIIQSVWDFIKSIVGLGVEIVKALIRAAWQGI
                     KDITSSIWEGIKSVIQSVWDAIKPYVMGAVDAVKTVVTNAWNSIKDISSTIWNGIKTV
                     VTNAWNGIKSIASGVSNAVKSVVSSAWNGIKSITSSIWNGIKTAVSNAWNNIKSSATS
                     SVSNVKNTTTSGFNSLKSAVTTIWNNIKTAISNVWSNIKTAVSNGANAVKSVCSSVFG
                     TISNILTAPFKTAQKAISGILGGITNKINGIKDKVSGLFRSGPMIPQNSNDFIQKDML
                     PTPIMFRTSVAGFASSRGSILDSIGKLSNTMTKGMGSPSGMISQFGRAGENSAKAYLD
                     GLSNIEEGLTNTLRAVQAIIGNGNIKEAQEIKKFNKEVQKLQEEKAEEIAELDKEHKK
                     KQKERNEKENEEIKEAEAKKYKNKKEKLAALKKIKDKYNKESVKDQEEYREKLEKINK
                     KYNKKEKEDTEKHQEELQKLREEKIKAERDFNKKYNDIKEDYAEKVANLDKKYIEDQK
                     KLNEEYQKIYDSRVKSLMDYTDLFSSVTFEEIDNDELMENLEEQVDVLRKWDTDMADL
                     STKVGKDLYEELLAKGPQAHNEIEAINKMSKEQLEEYERLYQEKKKIAERRAKEDTED
                     EKYRIEKEIEELKKTYDAEYRKLGQEMQRSIEEQIESFKDKFGVVPAMFMETGKDSMQ
                     GMIDGIKSMQGALGKVLSDIVNSINKQLSNIGFKDVNIPTGGRKEVARFRNEIENLQS
                     IAYSDTLARGIASNNLLKDATVNINNNSKVDSEKSSDKKVELTLHIEKFINNTKQDIE
                     QLGSEIAFITNRKLKF"
     gene            42444..42593
                     /locus_tag="KRM55_000559"
     CDS             42444..42593
                     /locus_tag="KRM55_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592830.1"
                     /translation="MNNFLLNVIAGVIASLIFCLISKIFAKVKSHSVRKSGWEFDLKI
                     KFHKK"
     gene            42754..43509
                     /locus_tag="KRM55_000560"
     CDS             42754..43509
                     /locus_tag="KRM55_000560"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HBH1592831.1"
                     /translation="MALQYCVSENELVSFQYGEINSRDFGIVITDINELASPERRFER
                     IEIPGRNGSLILDEGCYSNFNLEIECYIDVDGKDINILASEIKMWLQTDFSYKNLIIS
                     TDPNYYREAVCINKLDLEEIIKDLGYFKITFECKPLKKQLVNNLITINESDSKLINTG
                     MASYPLIKVFGNGDITLEINNEVIELTEVQGHIYIDCELMNAYKIDIHTNDVVNENSR
                     MFGDFPTFKHGENIITYSGDVEKIEIEPRWVVL"
     gene            43511..46279
                     /locus_tag="KRM55_000561"
     CDS             43511..46279
                     /locus_tag="KRM55_000561"
                     /inference="COORDINATES: protein motif:HMM:TIGR01665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH1592832.1"
                     /translation="MLRLYKANETNFKNNGLGILKDAVETKVTEELNGLFELEFTYYV
                     GSFLFDEIDYNKIVMADASPRLKNQLFRIYYISKELDGKILIKAEHISYDLLNNFIEN
                     LELKNVTCEEALNQIFRSCTEENRFVGYSDITGNKDFSISCVSPHNAISDIQELFNNK
                     SKLKRDNFNISLLNNFGESNNVLLAYRKNIIGLTATYDTQEVITKIYPYATKKSGKNK
                     KITLPEKYIESKYINNYPTQRIVAVDFSDDDVKNEESLRNKCKDYFIENNVDLPKVTY
                     KVEFVDLSTTEDYKSYKMLETVNMDDEIIVRDYNLGINATARVVKTEYNPVLKKYNSV
                     EIGDLVNHFKDERIDDLEEKIDKVQNNVDNIVIESDNFPDTLPEPSNVTALGLWSMIQ
                     LDWTFDNKLYYNYEVYASQIKGFEPDTAGYTNRIYVGQASSLLHEVKPMQTWYYRVRA
                     GNTHDNYNEFSNEVSATTRKLSDAAEYFEEAAIGHAIIRDLDADKINVGKVKGQYIEA
                     KNLVVVDGNSQTTLNIDSFGNVHVGATTFTLKGKSLESIIGGEIDNITQLEIFNKLTN
                     NGLAKGLYMVGNELYLNASYIKTGTLEGQFINGRNLTVRDNDGYTTLQVDSNGKVNIR
                     ANELSIGDKNNYESVLTSDQKAVFDALTGNRNCGIYLSGSRLYINADYIDTGTILCDR
                     IGASSSNPFILLFEGNGAKCALDATAQFGVGIGKAMRMKYNDYSYIYVSDDVISGYLD
                     GEEVFEFGYQDEKSYINTGLNTQHINPQIDGWYNCGSNRKAWDYLVCNNLNQLARTAA
                     TSTRMMKSTFNEEISNNCIDFVKSSLVQSDVFTPYNLKSMKNNNIEHRLQVDIDSSLD
                     NPISKYIFKDVSDEAGEGVYAQDITSHLAVLQLSLQKTISNFENYKDITSKKIEELTK
                     RIEVLESR"
     gene            46286..48505
                     /locus_tag="KRM55_000562"
     CDS             46286..48505
                     /locus_tag="KRM55_000562"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592833.1"
                     /translation="MRDRIYIVDINTKMYQIARYKQNDNNVSYNMRIVQDSIDVDLTG
                     YTALAFFNLPSGRVTQKNCTIEDSTVYTELSHIELSEEGDVISEITLYKDDKVVTTFS
                     TIIKVEKSINRNAIEDEPSWDIIKDILNVLSYEEERQENENVRKSNEEIRISSENVRT
                     GNENIRIESENQRKDSEVERCESEEVRKTQEVIREANEETRKTSETTREANEEIRNTS
                     EITREANEEIRKTNEIVRESSEETRNTNEETREVHETVRESNEEIRKTSEEIRESNEN
                     TRKVSEEIRNGSEETRVANEVARQESETTREENEDLRKSNEETREENEEIRKSNENTR
                     KASEEVRNTSEETRNTNEEARKASEEIRKTSETTRNTNEEARKVSETTRETNEETRKA
                     NEIIRQNSETKREENEELRKSNEVTRELNESTRQTSIINMQKKVDDKVDEVDNKIVEV
                     NTAKTDMTTTVSNKITEFEKRFNELENLDTAGEILQSKETTDGQIKDTLKERLTYDFN
                     KLDLKIEQLIAGGINVAFNKSYDTSEWIEVDGGFELSVEHNLVTQKILVSSIDKLNRK
                     SLITSYKIMDDNNIILFNEVAIDIEVTVVNGGSTIELIKFTINDDIESLESAYSSIET
                     KRLLKDGLDKKANLEHTHDIYVEKVEGKELSTEDYTTEEKEKLSQLDTYKNKETKFNT
                     NGSITETLDNSIKYITKFNTNGSISKEKYINDILINTTITNFKNGMIEESVTNEGVI"
     gene            48505..50385
                     /locus_tag="KRM55_000563"
     CDS             48505..50385
                     /locus_tag="KRM55_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016040100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH1592834.1"
                     /translation="MSWAEVYKINSDIQGEPLNYLNYLQDLKLNGSESYLLYEGNHRI
                     WEELYLNSLYLFSDRGIREVVYTAFSETDIDNLFDKSTKLGEQLNAFYRTDIFSLGNA
                     DNVVKGMTVEHYNSLEEKFKAGYDRYVTREQEKSTIGAWFNSTFSLNSTDLESLTTID
                     EILADTEATNAILNNSNAIVALTMCKSSMDAVVASPNAMDLLGQYILKVTAEPAVIKA
                     ILENNVIREAIINSTEAMTHIATNHESVRMIFENLEATQLLLANQDTLDLVLANTNVI
                     RLVLTKILETHNSIFKLDINTLITNMTSMVNSTNIEYQDKIFPIVETMNTNFISIKDL
                     LSNNNLDKNNIIAIFQCIENNLSVITALSSDEVAFNSIKEIDLAIAKTAAKLAGIDNI
                     NINTSDALARSDKYMNAVASSQIAMNAVASSQIAMNAVASSQIAMNAVASSQIAVNTI
                     INNSGFLNIVISSSTAMSAIASSSTAMLSISKSPLALNKILKTEIGRTSLANSSYLQT
                     NYSNISTSTQNTTYFAKGSNAVIDSGSRNSNDTGGMVSSTTPNQCIFICLTIGSWSNG
                     TNTTGTISHLQTGSQVATRTTTTGPIHQGTGATAQYICVGGCKFTESSDSGAWGCMAY
                     AK"
     gene            50420..52753
                     /locus_tag="KRM55_000564"
     CDS             50420..52753
                     /locus_tag="KRM55_000564"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592835.1"
                     /translation="MLNEDVVKNINKLNNEQDNINLELSKKANKEDLEKLIQGGPNVS
                     VSKDISINNWILEENVYTVIVEHNLVTRKVLVSLIDKSTNNNVFCSYQILDDNSIKVF
                     NESNNELECIVVNGNSAINMISATIDDNRSTETTTYSSVKIEALLKVLENKIDDIENL
                     KEIDNIKCSTNTGEYTIENSKKGYLTNFNIEGKTLIDLWGKTSSDFSLWKATFVDGKI
                     NILTENDIRYSNFFTINYTSYKPDTIYTIIVDVDKNTLPSTSGIYIHSLGEENSVFIP
                     NLTNIAIPGGVIGKFKYTFTTISDLSDCNVVLRSVLDNDTLTSGYEVSLKITILEGDY
                     TDINIDYSNELLSVGQRDKIEFLSYQYSGINIFNKNADFKDNYILQYLNGEELISEAS
                     NHKYTLDYIEIEPDTEYTFYNCSRNICWYDINKSFIPAPLNERIIGDKDIFYVARSPK
                     NAKYLRVTIIKDLHDNGNKTIITKGNKYDKKTIPYTLRSLPNGVKDEIVYKNNKYYLI
                     KRCEEHTYTDIGNLNLSHVYDNTLQFMGTLTPQAVVDSLDIAYVLCNNLNGKSRNDFN
                     NNDIEGCSTTGSGDIAFKILKSKLTTQDGNGFNEWIKNNPITIIYQLAEPQEIELTSL
                     NLEQYNNQTRFICNFGIVIPDISFESTQNLGSHIEVIRNNIKNYNVRTDFPFSINFLN
                     GWQPYLGYASAVGNYCTNNNFVTINATINGGVTTAGTIIGKIPSKYAPRKNIIVIFQT
                     TDGKYYNGIIRTNGEIEIYYNDITYRSWLYLYVNYLI"
     gene            52768..53094
                     /locus_tag="KRM55_000565"
     CDS             52768..53094
                     /locus_tag="KRM55_000565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592836.1"
                     /translation="MDIEKKIEILIEYGFENDLNNIDNYFIADGKKIFTPVIKNGELI
                     KTGEQVYNEWSELQNNPPKSEPSIEEINADKITILIENQKQQDSLLVDNAYRIAMLEL
                     NTNNVL"
     gene            53120..53272
                     /locus_tag="KRM55_000566"
     CDS             53120..53272
                     /locus_tag="KRM55_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592837.1"
                     /translation="MYNILKRMIEQKNYETKEELQTKLDVFYALNRIKENEYTELTNM
                     INKEEV"
     gene            53336..53602
                     /locus_tag="KRM55_000567"
     CDS             53336..53602
                     /locus_tag="KRM55_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592838.1"
                     /translation="MEQLLTELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVEMGAMKTDVEEIKEDVTDIKVMLQKEGDK"
     gene            53602..54408
                     /locus_tag="KRM55_000568"
     CDS             53602..54408
                     /locus_tag="KRM55_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1592839.1"
                     /translation="MKVVIVPGHTLTGKGTGAVGYIDEGKENRVLTDLIVKWLKQGGA
                     IVYTGKVDKSNNYLAEQCEIANRQNVDLAVQIHFNANKTTLNPMGTETIYKTNNGKVY
                     AERVNKKLSTIFKNRGAKSDVRGLYWLSHTKAPAILIEVCFVDSKADTDYYIRHKDIV
                     AKLIAEGILNKIIDNKENGEGKIMYKHTIIYDGAVDKIPATVVGWGYNDGKILICDIK
                     DYIPGQTENLYVVGGGACEKIGSMTKENYTMIKGNDRFDTLYKALDFINK"
     gene            complement(54453..54629)
                     /locus_tag="KRM55_000569"
     CDS             complement(54453..54629)
                     /locus_tag="KRM55_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBH1592840.1"
                     /translation="MEQRELNISFHKSGNGYTTTRLSLPINWVKELGISQNERKVIVT
                     LEDGKIIIEKAENE"
     gene            complement(55326..55511)
                     /locus_tag="KRM55_000570"
     CDS             complement(55326..55511)
                     /locus_tag="KRM55_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBH1592841.1"
                     /translation="MILLEQRKLRVAFNKSGKGSFTPRLILPMSWIKEMNISPDERDV
                     LVTFEDGKIIIEKAENE"
     gene            56236..56913
                     /locus_tag="KRM55_000571"
     CDS             56236..56913
                     /locus_tag="KRM55_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1592842.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            57082..59118
                     /locus_tag="KRM55_000572"
     CDS             57082..59118
                     /locus_tag="KRM55_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBH1592843.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(59309..59875)
                     /locus_tag="KRM55_000573"
     CDS             complement(59309..59875)
                     /locus_tag="KRM55_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1592844.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKKD"
     gene            60163..61098
                     /locus_tag="KRM55_000574"
     CDS             60163..61098
                     /locus_tag="KRM55_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase"
                     /protein_id="HBH1592845.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRCSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
BASE COUNT        25156 a         6500 c        10793 g        18649 t
ORIGIN      
        1 atacatttac ttagaagtat tattatattt ggatttttgg tttttataat ttttttatat
       61 ttaaacataa ctaaaaataa aagattacta aagctaagta gagtttattt tattttaata
      121 aataataaag ctatttttct atatattggc ataatatatg cttatttaac tatgaaatta
      181 aaattaaata ggattaatga ggaggaaaaa aatgggaagt aatgaactaa aaaagactct
      241 tggcgtatca gcagcattat caactgttgt tggttccgtt ataggagcgg gcgtattttt
      301 taaaccacaa gcagtctata cattaactgg aggagctcca ggtcttggta tattggcatg
      361 gttaatagct ggaatcataa ctataacagc tggtcttaca gctgcagagg tatcagttgc
      421 gataccaaaa actggtggaa tgatggtata tataaaagaa atttatggag aaaaattagg
      481 ttttttaact ggatggatgc aaattgtatt attttatcca gggatgatgg cagcattagg
      541 tgttatattt ggagaacaag catcagcact aattggtagt ccatcacttt tacttccaat
      601 agcaattgga attatagtaa tagttgcagg gcttaatatg ttaggttcaa aaactggagg
      661 agtcatacaa actgtttcta caatttgtaa gttaatacca cttattttaa taatggttgt
      721 tggatttatt aaaggtggtg gaaataatcc aatacttaca cctatggttg gtgaaggatt
      781 aagcctgggt agtgtactag gtcaagtttt aattgctata ttatttgctt ttgatggatg
      841 gatgaatgtt ggtactttag ctggagaaat gaagaatcct ggaaaagacc ttccaaaagc
      901 tataataggt gggttgtcag ttgttatggc tgtttatttt ataataaatt tagcatatct
      961 ttgggtatta ccagctaatg aattagcaaa ttatgcttct cctgcatcag cagttgctga
     1021 agttatattt ggttcaatgg gtggaaaaat aatatctgta ggtatattaa tttcagtgtt
     1081 tggagcatta aatggatttt tactaactgg ttcaagggtg gcatatactt tagctacaga
     1141 taagacttta ccaaagtatg gtatattttc taaattaaat tctgctcaag ttccagcaaa
     1201 tgcaatagca ttagtatctg ttattgcatc tatatatgct ttgtcaggtc aatttaattt
     1261 attaactgac ttagctgtat ttgctacttg gatattctat gtattaactt ttataggggt
     1321 tatgaaactt agaaagactc atccaaatat accaagagag tataaagttc cattatatcc
     1381 tattgttcct ataatagcta tagcaagtgg tatatttgtt gtagttaatc aattgtgttt
     1441 tgcaggtatg aaaactacta tgatatctat aggaggtctt gtaataacag ctataggctt
     1501 accagtgtat gcttatatga ctagaggagt aaaaagataa accaagtagt ttacaaatgc
     1561 ttcataatta aaataaaaga gactgtctca aatagagata agtctctttt ttattgttaa
     1621 aatggtaaag atatgtttga ttttacaaaa aaagagcgtt ccatgaacta aaaagtttat
     1681 tttaaggtat tcattttatt tttagttttt tgattataaa attaaacatc taaaaaatta
     1741 tttattttaa aatactttat tttaaagtgt tttttatcaa actaagtggt atctgtacaa
     1801 caaatattat acatagcttt tatgaaaatt aaatctttct gttatatata atagaatatt
     1861 gtattatata gaaaatatta cctgattaat atagtgattt ataaatgaga ttagaaaatt
     1921 ttatttgata acaaaaatta gatagtatga atatataatg tatgtattaa aaatgtggca
     1981 aatagttgtt ttgctattta ttatttgttt aatatttcta atttataaaa aaaaaattat
     2041 aaattttaaa aattataaat gacattttaa ctagaattaa ttgtaaaaaa cactatataa
     2101 tactcaattt tcaacattct atacaattat acagaaatta tacagcataa taatcaccga
     2161 aataacaaat tttaaaaatt aagcaaaact ttttgtcgaa gttcaacgtc tatatatatg
     2221 tagtgtaaat ttttgggata aaatactaca aaaatataaa tgtaaaaata tagtaatatt
     2281 ggaggtcgaa cgatgagaaa taaaaagaaa aaaataaata gaaagaagtt gtatttgctt
     2341 ttaagtgcta ttgtagtgtg tctggctttt atagtagttg gtgttcgcgt cagctcttta
     2401 aatatgaagg aaaatgaaat tagtagaaat gcaaaactgt caagttctac tattacagat
     2461 atagtatcta atacatcaat agaagttagt aaagggccaa gtaaaagttc tggaaaaata
     2521 gcatacataa ctatagatga tggtccatct aaatttactg acgagatgat aaaaacttta
     2581 aataaataca atgttaaagc aacttttttt atgatagatg ggaatatgaa ggaatatcca
     2641 cagcaagtta aaaatataat taaaaatggg aacacagcag gttttcatag tgtatcacat
     2701 gatattcaca agctttatgt tactagtaca tcagcaaaag aggaatttga tacaaatgat
     2761 caaacttttt ataagataac tggtaaacat tcaaaagtaa taagaatacc ttatggaagc
     2821 aaaccatata caccacaagc ctcttatcag gctttagttg atgctggata taaaatttgg
     2881 gactgggact tagatacaga agactggaga tctaattctt ctcaaattgt acaaaatgta
     2941 aaaaatcata ttaagaatag aaaaggtgaa gataaagacc aacttgtagt tttaatgcat
     3001 gagaaaaaac agagtgcaga agctttagat tcagttttaa aattcttatc agatgaaggt
     3061 tatgaatttg cgccagtaga tcaaaaccaa ataccaaaaa attattggtt acgtaattta
     3121 gagtagttaa aatataagaa tattgattga tatttttaga aattgagaat aaaaatgagt
     3181 gaggtgtagg tatattgaat aaaaaacttt atataggaat ggtcggaata ttgtctttga
     3241 tgatggttgg ttgtaataaa agtttagcaa aagtaaatga tgtggaaatc acaaaagaac
     3301 agtacaaaaa aacaaaagca gttttatctg ctactaataa ttatataaat gggcagtctt
     3361 tagatgaatt agaaaaaact ttggataaaa aaggtagaaa taaattagaa aatgttataa
     3421 tatcgtttat ggtggataat gaacttttat atcaagaggc taaggataaa ggactaactc
     3481 caagtaaaag tgaagtagac tcaaaatatc aagaactaga agataagatg aatttgaata
     3541 caagctataa ggaaaaaatg gacaaagcag gtgttgataa agattattta aaacaagaaa
     3601 tatctagaga tttagcaata gataaaaata aaaaggcctt tgaagataga ataaacataa
     3661 gtgataatga tatggaagcc tactatacaa gtcataaaaa agattttaat gtagaagaag
     3721 taagtgcttc tcagatactt atatcgactt tagataaaaa taaaaaagaa gtaagcaaag
     3781 ataaaaaaga agctttgaag aagaaggcag ataatatatt gactaaaatc aaaaatggag
     3841 aaagttttga aagtttggct aaaaaatatt cggatgataa agcaactgga aaaaatggag
     3901 gacagctagg atattttaca aaggatgata aaaatgctga gtttacaaag gaagtgttca
     3961 aattaaagaa aaatgaagtt tcaaatgtgt ttgaaactag ttatggatat catatagtca
     4021 aagttactga taaaagagaa agacaaaaaa gttttaatga gtgtcagagt ttaataagag
     4081 aatctatttt aaatgaaaag tatattgagc atataaaaaa actgaatgaa gatgctaaaa
     4141 tagacagata gaatttctaa cagctcaatc ctagcctgta atcggaggga gattttacag
     4201 gaatgtttaa gagtttaaag agaacgaaag ttgagaaata cattatcgat aataaagact
     4261 ctttttatag aatagcatat agttatacga agaatgaaga agatgcctta gatgtggttc
     4321 aagaagccat gtataaggca ctatactcag tggaaaatat taaagaagta aattatataa
     4381 agacatggtt ttataaaatt ttagttagaa cgagtataga ttttattaga aaaaaccgta
     4441 aatataataa tatgacagat attgacctta tagatgagac tggagagtat gataaatata
     4501 ctgatttgga tttaagaaga gctttggaag aattacctat tgaatacaaa tctattataa
     4561 tattaagatt ttttgaagat ttaaagattg aagaagtagc aataatattg gatgaaaatg
     4621 tgaatactgt taaaactagg ttatatactg ctttaaaaaa actaaaatta aaaattgaag
     4681 agtagggata aaaagaatga caagcaaaga aaggttaaat aagttaaaag atgagtatca
     4741 taaaattcca atacccaaga aattagatac tataataaat catgaaaaaa tagaaaacat
     4801 atatcgagag aaaaataaaa aagtaaatag attaagattt aaagttgcaa tagcctttgc
     4861 atgtatattt acagtattag taaatataag tcctgtattt gcagacaatt tttctaagat
     4921 acctgtaatt ggagcaatag tagaagtaat aactataaaa aattatagtt taaaaagtga
     4981 aaattatgaa gctgagattg atattcctaa aatacgaggt ttaaaagata aaaacttaga
     5041 acaaagatta aacagtagtt ttatggaaga tggaaaaagg ctttatcatc aattccaaga
     5101 gagaatggag aagatacaat catcaaagaa taaaggatat aaatctttaa gtttgagtta
     5161 tagtgtaaaa aataattcta aaaaatttct atcaatagag atgacaaaaa atgagataga
     5221 ggcttcatca tatgtgagta aggtacatta tactattgat aaaaaaagac aaatagtttt
     5281 gactttgcca atgcttttta aagatgataa gtatataaaa gttataagtg ataatataaa
     5341 agaacaaatg agagaacaaa tgaaaaagga tagtacaaaa tcctatttta tagatcaaaa
     5401 aaaagatttg cctgttgaag attttaaaac aattaataag tatcaggatt tttattttaa
     5461 taaaaatgaa gaccttgtaa tttgttttga tgaatatgaa gtagcacctg gttatatggg
     5521 tgcagttgag tttgtaatac catataaagt aataaaagat ttgtaaattg aatagtagtt
     5581 tatatataaa tattttaaga aggacaatat gactacatat aaaaagctta aaaaatctat
     5641 atttaaaatt gctatatttt caatatgctt attagtttca ttagtagata caaaccctat
     5701 atttgcaggt agttccttta atgaaacttc aaatagtgat acgataaagg tgttaaatac
     5761 taagagtatc aactttaaac aagacaatta tgaagtgaat gtgagtattc ctaaaataaa
     5821 aggtttaaaa gataaaactt tagagaataa attaaacaat gagtttttgc aagatgggaa
     5881 aaaaatttac agtgaatttc aaaataaaat gaaaaaggaa gataataagg gtcatagata
     5941 cctaaatgta atccacaatg tcaaaaataa ttctaaggac tttttatcaa tagaaatgac
     6001 aaaagaagag atagaagctt cctcatctat aactaagaag cattacactg ttgataaaaa
     6061 tagaggaata ctattaaatt taccaatatt ttttaaagat agtagatata ttagagctat
     6121 aagtgataat ataaaagagc agatgagaaa tcaaattaag aaagatgata caaaatctta
     6181 ttttatagac caagataaag actcgccagt gaaagatttt gaatctataa ataagtatca
     6241 agatttttat tttaataaaa atggaaatct tgtgattagt tttgatgaat atgaagtagc
     6301 acctggttat atgggagcag tagaatttgt gataccaaat aaagtaataa aaagactaag
     6361 atagatatat agaagatttt tagatagact ggtaaggaga attatatgaa tatatatgaa
     6421 caagcaataa gattaataga aaataatgag gatttcgcat ttgctacaat aacgtctcat
     6481 tcaggttcaa caccacgtga aactggagca atgatgattg tgaaaaatga ttctactata
     6541 tttggctcag taggaggagg tagtgtagaa gcagaatgta taaaacatgc aattaatgtt
     6601 ataaaaaaca gagaatcaat gttgtataaa tttactctaa acaaatctga tgtggcaaaa
     6661 ctaggaatga tatgtggagg tactggagaa atacaaatag attttataga tagtaaatta
     6721 aaaagtaata tagaaaaatt taataagaga ctaaaggaaa atacaagtaa agcatatata
     6781 tttggtgcag gtcatatttc aagagatgtt gctgtgatac tatctctttt agaatttaga
     6841 acagtagtaa tagatgatag agaagaattt gctaatcatg aaaggtttcc agaatcagaa
     6901 gtagtagttt tagattcttt tgaaaacata ccagattttc caactgacga aaatagttat
     6961 ataattattt taacaagagg tcatctatat gattcaagtg ctttagaatg ggctcttaaa
     7021 agagaggctg gttatatagg tatgattgga agtagaacaa aaattggatt gacttacgaa
     7081 aaactcatga aaaaaggttt taagaaggaa gaattatcaa aagtacatgc accaataggc
     7141 ataaaattga atgctcaaac accagctgaa atagctgtat gtatagctgc tgaacttata
     7201 aattgtagag ctaataagga aaaataaact aatgaacaca gggagtaaag atattgatac
     7261 tttaaaggtt aattttagag ggattgaaat aaaagcagtt ttagtatata aaaatagaaa
     7321 aaatatttct ataaaaatag atccatttgg caaaataact gtaatgagtc ctcctaaaat
     7381 atccaaaaaa ataataaaag atataattat tgaaaaagga gactggatac ttaaaaagtc
     7441 agaaaaatgt aaaggaagag aggaagtata taaacaaaga atgtttataa ctggcgaaaa
     7501 atttctttat ttaggtgaag agtaccatct agttataaaa gaattgttga gagattctgt
     7561 caaaaaaagt aactgtagaa taactattaa cgaatatcaa atagttgttc agacaaatga
     7621 tacaagtaca gattttatta aaaaatcttt aaaatcttgg tataagatgg aaagtgaaag
     7681 aatagtatta gagagaatag attttcttaa attaaattgt gaaataatga agcaattagt
     7741 tccagcgagt gttaaggtaa aagaacaaaa taagagatgg ggaagttgta cagttcaaaa
     7801 aaatatttat ataaactcaa aaatatctat ggcaagatta gatgtaattg attatgtaat
     7861 aatacatgag tttagccatt tagtacatat gaatcactct aaaaaattct atgatttagt
     7921 aaaatccatt atgcccgatt ataaagataa agaaaattgg ctaaaaataa atggatataa
     7981 aataataatc tgaaaacgat tattcaaaaa tataggcgta aagtataaaa gaagtattat
     8041 tgtgaaaaaa ataaataatc tgaaaatttt aaaaaaagtc attgacattg taaatgatag
     8101 ggaatataat ctatattaac aacaaaacag aattaaaata taaaattaaa aaattaaaag
     8161 caatgacaga gacaacaata ctaatagtgt tatccacaga gaaccaatgt tgctgagaat
     8221 tggtgttaac agtagtataa tgatcactct ggagcttttg tactgaatat ttttagtaag
     8281 tacaaacgta tgtcaacgtt acatgactaa ggttaaggta attaattacc cgacctgaaa
     8341 aaagaggggt agatgtattt tttatatcta caaataaggt ggtaccgcgg aatataactt
     8401 tcgtccttat aagtaatatt tatattgctt ataaagatga aagttttttt attttaagcg
     8461 atataaataa atttaatcca tataaaatta ataaaaaaat aataaaaata aggagggatt
     8521 tttatggaaa atactgtata tgctaaatta aaccaaggaa tagattcttt tttaagagtg
     8581 gctatgactc taagaagaag agaggttgat atacaatcaa taagtatgac tgtagataat
     8641 atgaataatt caggtataaa attaatagta aatgaagaaa agacatcctt agattctgtc
     8701 ttaaaccata tgaaaaaact acatgatata agagagataa ctgttgaaag aatgagacat
     8761 taattaaata tattttataa agctaaagat aaatatgctt attttaaaat aaaaaactaa
     8821 agataaatat taaataagaa aaatcttaga ttaaaatata agtgtcattg aatttattag
     8881 tttatcacag ttaataaatt tattagtttg ttgtagctaa taaaaactga aaattctaaa
     8941 attataattg taagattata taaatttaga atttaaatct gttgaataat attaaaacaa
     9001 tgataatgag tatgaatttc taataaaaat aaatatcata aaaataagaa aaagtattgg
     9061 gaggaaatga aaatggcaag aatgtattat gaaaaagatg tggatttaga ggttttaaaa
     9121 aataaaaagg ttgcagtttt aggttatgga agtcaaggac atgcacatgc acaaaatctt
     9181 agagataacg gtgtacatgt aatgataggt ctttatgacg gaagtaaatc agcacaaaaa
     9241 gcaaaagaag atggatttga agttaagagt gtagcagaag ctacaaaaga aagtgatttg
     9301 acaatgatgt taatgcctga tgaaaaacaa aagaaagttt atgaagagag tgtaaaggat
     9361 aacttaaaag aaggtcagac attagctttt gctcatggat tcaatataca ttataatcaa
     9421 gtacaaccac cagaatttgt tgatgttgta atggtagctc ctaaaggacc tggtcactta
     9481 gttagaaatg tatttacaaa gggaagtgga gttcctgcac tatttgcagt atatcaagac
     9541 tacactaaaa aagctacaga gacagtttta gcatatgcaa aagggatagg agcaacaaga
     9601 gcaggtgttt tagaaactac ttttaaagaa gaaacagaaa cagatttatt tggagaacaa
     9661 tcagtacttt gtggtggaat aagtgaactt ataaaattgg gatataaaac gcttgtagat
     9721 gcaggttatc aaaaagaagt agcatatttt gaatgtttac atgaaatgaa actaatagtc
     9781 gaccttatat atgaaggtgg atttgaaaga atgagatata gtataagtga cacagcagaa
     9841 tatggagatt atgtatctgg taaaagggta ataactgatg ctgcaaaaca aggtatgcaa
     9901 aatgttttag aggatataca aaatggaaaa tttgcaaaag cgtggattaa agaaaatgaa
     9961 gaaggacgtg aaaacttcct aaaaactaga gaagaagaat ataatacaga aattgccgaa
    10021 gttggtagaa atctaagaag tatgatgtca ttcttaaaat aaatatatat taaatggatt
    10081 agtttgaggg aaagagtggt gtatagtagt gcgtatgaat ggagcaaagg taattttaga
    10141 atgtttaaag aaagagggaa ttgacacaat atttggatat cctggtggag ccgtgatacc
    10201 tctttatgat gctctatacg attattcaga tgattttaaa catataagga catcccatga
    10261 acaaggttta gttcatgctg cagatgggta cgcaagaagt actaatacag taggagtttg
    10321 ttttacaaca tctggtccag gagcaacaaa tgccataact ggaatagcaa cagcttttat
    10381 ggattcttca cctatggttg taatttcagg gcaggtgcca actagtttat taggaaaaga
    10441 ttcttttcaa gaaattgaca taactggagc aacattatct atgacaaaac ataattattt
    10501 agttagaaac actaaagaat tagttcctac aataaaagaa gcttttagag ttgcaaattc
    10561 agggagaaaa ggacctgtac ttgtagatgt tccaaaagat ttatttttag cagaaatgga
    10621 ttttagtggt gaggactatg atttatgtca aatagatgat tatatggatt ataagagtga
    10681 ttttgatcta gatgatgaaa ctaatattaa gcttttaaat gaagcaatag atatcataaa
    10741 agaatctaaa aagcctgtaa tatatgcagg tggaggtgtt aaatcttcag acagtgagga
    10801 aattcttgaa aaatttgcaa ctaagataga tacacccgta ctaaatacac ttatggggct
    10861 tggaaatata gatagaaaga atgaactatc tcttggaatg gttggaatgc atggaagtag
    10921 agaaagtaat ttagcacttt ctaattcaga tttagtaata gcgataggtg cgagatttag
    10981 tgatagagtg ataagtaaaa gttctgaatt tgctaaaaat gcaaaaataa tacacataga
    11041 catagaccca tctgaaataa gtaaaaatat agaatctaat gtatctttgg ttggagatgt
    11101 aaagctagtc cttagtttat taattgaaag ggttgaaagt aagaataata gcaattggaa
    11161 agaagagata aagagattta gaaagagtga gggtgtacaa acatatgaat ttcatccaca
    11221 aaatatactt aaaaaaataa atgaaaaata tgaaacatta aagaaaccca ctgtggtagt
    11281 aactgatgtc ggtcaacatc aaatgtgggc tgctaaatac tggaatttta aaggtaataa
    11341 aagttttata acatcagcag ggttaggaac tatgggattt ggtttaggtg cagctattgg
    11401 aactaaagtt ggtaatgtag ataaaaatgt agttttagtc actggtgatg gaagttttag
    11461 aatgaactgt aatgaactag ctacagttgc aaattataat gtacctatgc ttattttact
    11521 actcaataat agaacattag gaatggtaag gcaatggcaa aagttatttt ccaatcaaag
    11581 atactctcaa actgacatta atgaaaatgt ggattatgtt aaactcgtaa atgcatataa
    11641 tattgatgga tataaggtat ccagtataga agaattagga aaggcgctag atatgataga
    11701 ttttaataaa cctgtatttt tgcaatgtga tatagataag gattatgatg tttatcctat
    11761 tgtagcacct aatgatgcat tggaaaattt gatatgtaac taaaacttat actgaatatt
    11821 gataaaattt tttattaaat ttttattggt attcagtttt tgttgtttag agatagattg
    11881 gcatttttta ttttttcaaa taaatcaatg actatataat taagaactta ttaaatttta
    11941 attatacaat ttggaatagt attacaactt aagtaaatat taagttttat tcattagatt
    12001 tattattaat accttatatt agttatggtt gttatatact ctaaagcctt gaaattacat
    12061 gcgtatagct gactatataa atttgataat tttagctttt aaaatagata aattagattt
    12121 tgccacccat ttgccaccgt attatatttt tgggtggcaa actctaattt gtaatttttt
    12181 caaatatatc tacagtttca tttttcattt tatcagttac atgtgaatag gtatccattg
    12241 tagttgatag ttggctatga cccaaacggt tttgtatgtc tttaatgtta gcaccatttt
    12301 ctaataatag agtagcatgt gcatgtctta aagaatgaaa atggaagtca ttgtttaaag
    12361 ctactcgaat ttgtcttact atagtgtcta aagtgtgagt attcacttgt tgaccatttt
    12421 ctttggtaca tacccagtca ctatcaaagt aaaattctcc atattttaat ttcattttct
    12481 tttgatataa tttatgttct tttaatgcct ttattaaagt gtcacctgta aatatagttc
    12541 tgcaagagct ttctgttttt ggttgcccta attcaaacat tccatttggt tttttaatca
    12601 aagtatgctt tactgtgata gttttattat caaggtctat attattccat tttagtgcaa
    12661 taatttcacc tcttcgcata ccagtatgaa atccaattag taaaactata cgttgaaatg
    12721 aatcttgagg aaatatattt agtatttgat taaattcttc taatgtaata gttttaactt
    12781 tattagtttc tgttttagat ttagtttttg gtatgcttac atattgcata gggttttctc
    12841 gtatgtgttt gtaaggatgg actgctgatt ttaatgacct atgtaatatg gcttttaata
    12901 cttgtaatgt attttgagag taatcctctt tgtacttttt atttatgaag ttttgtagta
    12961 ttgcaggagt taaagctttt actttgtaag ctcctagttt tggctttata tgtttttcta
    13021 tgtttattcg gtagctttct tgagtgttgt atttacagtt aagtaagaca tattctttgt
    13081 accaaaaatc taagtagtct gataaactga tgttgctttc ttcaaatact atgccagagt
    13141 tttcatattc atttagtgct tctcttaagg ctttttcggc ttctttttta gtattgcctc
    13201 caactctttc tacttttttt ctttttcctt ctactatgcc taggtcaaag tagtaatacc
    13261 atttgttact tctttttctt actccacctt tcataatagt atccctccct tttagaatgt
    13321 atgtttgttt ggtgtttata taaaagagca ggttaactgc tctttatata cttttgttat
    13381 gtacaagatt atcttaattt tgtttatctg gatttcactt aattattttc ttaatattct
    13441 tacaattttt ttagctttta tgtgtagttt attataataa tattgaaata tatatttatt
    13501 aagtaaaaaa tctataaaag tagaataaat gagtttaaaa aatatcctca tatatgtaga
    13561 aatttggcaa attagttaat actaaaaatc tattatttcc taagtccaac atgcttttct
    13621 tttttgatag aaattctaat ctttttagta agaagttgat gctaacttgt aattcttcag
    13681 ctatttcgta tacacttgta gcgtgtgaat taataacatg tattatttct tcttctgtta
    13741 taagaaattc acatgcccat tttagtgctt tgttttcagt tttgtctatc aagattttat
    13801 ttttgtaact gttttttgaa gatacatagt ttccaacact ggtaaaatga tgtcctaatt
    13861 cttctgctaa gatttctatt agtttagcat tgttttgttt taatgaatta agtaatgata
    13921 taatctttag tccttgtctg tttatataca atccttttat gtcatctgct attttgtcag
    13981 tgtagtaaat ttctatctct tcattatttg ctaagtctaa aagtgcgtct agtttattca
    14041 ttgaaatccc cctaaaaaaa gaaagtatgt ttgatgtaga gctttaaagt aacccagtaa
    14101 agggttacta gttaatttaa taaatgcact ctccataaga atatttattt tacaagttct
    14161 ctaattgcag atactataga atctgtattc cagttaacaa ttttattagc attatcagaa
    14221 acataagtag gaatattaga atttccataa ggtcttattc ctaatattgg ctttccaatt
    14281 ctaattgatt catcaatttc gtattttatc caatctttat attgaacata cattccagat
    14341 ataacaattg ttatttgtga aggagatatt ttatctgtta tttttttagc tatatctgaa
    14401 ttgctaaaag gtgttccatc tggaaataaa ggtttttctt ttggtgcaga ataattataa
    14461 taactaaagt tattagcatt atttagtaag tttatcaatc tatcatagtc attaccatat
    14521 ttccaagcat gacttatgaa aactctataa tcatataatt taggcatagt atattatcct
    14581 ttcttttgtg atataatatt ttacaaaata atatttatgg aggtgctttt atgcaagtaa
    14641 aaaagtttag aaaaaagcca gttgttatag aagcttatca gacagatata gaatttatta
    14701 tacaaacatt agaaggtcct ttaaaagcat ctattggtga ctggattata actggtgtaa
    14761 gaggagaaca atatccttgt aagccagata tttttgaaaa aacatatgaa gctgtagatg
    14821 atgaagttcc tttaacatca tttattgtat agttttttat atcattaaga gttcaaattg
    14881 agttctgtcc aattttcatt ttctctattt agaatgtctt caattctttc tgtaaataaa
    14941 ttgaaggcat tttcatttat gtaaatatta gtcctagtta gaaataaaaa cttttctctt
    15001 tttaataatt ctgcagtata tctatattta atccacaagt cttgccattt aaataaattt
    15061 cttaaagatg aaaaaataat tactactata cttaaaatag ttattatatc tgctatatgt
    15121 tcattttcaa atgaaaattt cgataaagca gttattattc cagctataat tatttctata
    15181 acttgaatag taaaaaattt ttttttaata ttactacttt tagagctgta ccaatttatt
    15241 tgtttattca ctctattttc taaatattgt tcttctgaca tagttcctcc tatttcttat
    15301 atttattcat taaaaattca atataatcat taagctgttc ttgagcttct tcaggtaaat
    15361 cctcatgtgg atttgctttg tgtgcggcta cagtgtctat atgatttcta acaagtgttg
    15421 tacctaaaag ataatctgtt gtaacatcaa aataatgagc aagctttata atatcatcac
    15481 ttttaggtga aattatatta ttttcatatt tagataataa atcagtactt atttctaatt
    15541 ttttgcctaa tatatttaat gtgacacctt tttcctttat taattctctt aatctttttg
    15601 agaaaatagg atttaaagat tttactactt gattgggatt ttttatgtct gttttaccaa
    15661 gtaagtaatc tgttgataca tcaaaataat ttgaacagtc ttcaataaaa gattgttttg
    15721 gctctcttaa cccattttca atcctagata gagtggattt atttacattt aaatccatac
    15781 ttaatctatc taaagatatt cctttttctt ctctcagttc ttttaatcta aacatataaa
    15841 atcatccttt attgtagttt tcattatagc aacttttatt tacattatag caactttttt
    15901 tgttattaca attaaaattg ccaaaaaagc aacaaaaata ttgactttta acatttttgt
    15961 tgctattata taaacaagaa cttgcttata tagcaaaaag ttagagggtg aaaaaatgta
    16021 tgtcaataga ttgaaagggt taatgaaaga aaatcaacat acgcaaaaat ttgttgcaga
    16081 tttgttaggt cttagtttat ttggctttag gcttaaactt aatggtaaaa atgagttcaa
    16141 agcaaatgaa ataaaaaagt tgtctgaatt atatggagta tcaacagact attttttttc
    16201 agaatcagtt gctaaaatgg caataaaatg atgggtattt tatagagagg agtttgtaaa
    16261 tatgaaagat ttaaaaatag taaaagttaa taataaacta acaactgaca gtagagatat
    16321 agctctaatg gttgaaaaag aacacaagat tttactaagg gatataagaa attatataaa
    16381 ccaaatggaa gaagccaata aaaacatgag tacagatttg tacccatctg attattttat
    16441 tgaaaatact tatttcgatg attataaaag agagaaacca tgttatgcca taacgaagat
    16501 aggttgtgac ttcatagcaa ataaaatgac aggtataaaa ggtacggcat ttacaggaat
    16561 atatacaaaa aaatttgatg aaatggaaaa atatttaaaa aatgaaccac aacctaaact
    16621 accaactaca tacaaagaag cgttacaaca ccttatagag caggtagaag taaatgagaa
    16681 attgcaacta gaagggaaaa tgaaagacca agtaataaaa gaattaaaac caaaggcaga
    16741 ttatacagat atgatattaa aaaataaagg tcttgtcact ataactcaaa tagcaaaaga
    16801 ctatggaatg agtggaaaag aaatgaataa aatacttcat gaaagaggga ttcaatataa
    16861 acaaagtgga caatggcttt tatataaaca atatcaaggg aagggataca ctcattcaga
    16921 aacaatagac ataactagaa gtgatggaat gactgatgta aaaatgacaa ctaagtggac
    16981 tcaaaaggga agattgtttt tatatgactt attaaaagta aataacatat taccagatat
    17041 agaaaaagag tatagttatc aaacttcaat gttaggttag tactttgaaa aataaataca
    17101 gaatattcaa aaagaggtga tttaaaggtt gagtaataga aagaagtata ccttgagtat
    17161 tacgaaagaa ttatacaata aatgtaaaga aaaagctaat caaagaggta tgtcagtaaa
    17221 cgagtacata ttatcagtga ttagcagaaa tttagaaaat gtttaatttt tattagctta
    17281 aacattaatc ttaccattta ttttttcata attttcaaca tgttttttaa ttaattgttc
    17341 tatttcttta ttggcagaac gaccttcgct ttcagctata tacttgattt tttcaagtag
    17401 attattatct attctaagtg tgtatctagg taattttgat ggcataaata tagcaccctc
    17461 cttgagtctg aatgatgtca ctattatacc atgtaaattc tttcaaaaaa agtattgacg
    17521 caaaggtgac gcaatgttaa tataataaac aaggaggtgg ttcaaaagtg acggcaaaaa
    17581 agagagtgac tgttagaata ccagacgaat taaatgaaga gctacatagg caatcccaaa
    17641 gaaaaggatt aagtaaaaat gcttttataa taaatatctt atggaaagaa tttgaggatt
    17701 tgcaagactt aaaaaatgaa caggaggttg ataagtatga ataacttaac aattatcaag
    17761 caaaacaata aatatttagt tgagagtaga gaggtagcag aattaataga aaaagaccat
    17821 aaccaattat taagaagtat aagaggatat ataagtgtat tagagcagag tgcaaaattg
    17881 cacactgatg atttttttat tgaaagcact tataagaatg aaaataatca gaaatatcct
    17941 tgttatctat tgactaaaaa gggttgtgat atggtagcta ataaaatgac aggagaaaaa
    18001 ggaattatat ttactgctat ttatgtaact aagtttgatg aaatggaaaa gtctttaagg
    18061 aatgaaccac aacctaaatt accaactaca tataaagaag cgttacaaca tcttatagag
    18121 caagtagaag taaatgagaa attacaacta gaaggaaaaa tgaaagacca agtaataaaa
    18181 gaactaaaac caaaggcaga ttatacagat atgatattaa aaaataaagg tctagtcact
    18241 ataactcaaa tagcaaaaga ctatggaatg agtggaaaag aaatgaataa aatacttcat
    18301 gaaagaggga ttcaatataa acaaagtgga caatggcttt tatataaaca gtatcaaggc
    18361 aagggataca ctcattcaga aacaatagat ataactagaa gtgatggaat gactgatgta
    18421 aaaatgacaa ctaagtggac tcaaaaggga agattgtttt tatatgactt attgaaaaca
    18481 aataacatat taccagatat agaaaaagag tatagttatc aaacttcaat gttgggttag
    18541 tacttagaaa attagattca aaatatataa aagagaggtg tattttaatg aatgaaaagg
    18601 atacaaagat tacagaaaaa gatttacact atattactga ttatcttctg aaagagtctg
    18661 atatagggaa aagattggct ttgcttgaag aaaaaacaaa gccaataaaa atagatgaaa
    18721 taagtgatta tttatctaaa agaatttcag ataagacttc tttaacatag tttttagtaa
    18781 atgcaatatt ctcaaaataa aaaaacatac aaagctctgt attacttatt tcactagtag
    18841 atttttcttt tagagaaata aattcactaa ttttattcct aagaagtgtt tcatctgaat
    18901 attcactttt tagtattctg ttgtacactt cgtcacaaat tttatttaac tcgtccttat
    18961 tcatattttc accatccttt gcttatgtat tggaagtatg tgggaatact tcttgagtca
    19021 attataacat gaggtatgga gctgaaaata atatatatag gattttggta ataatgcgta
    19081 gatataaaat taattttata tatttcatta aaaagagggg agagaatttt cacatggata
    19141 tttctgaaag tatagcaaaa caatttagtg atagtttaaa aagtttaata gaaatagaga
    19201 taaataaaca agaaacagat agagttaaga gtcaaactgt tgaacaaaag gtaaaagtac
    19261 tagaacctaa agatatagtt gttttaataa aaagaggtta tccaaattac ttgataacag
    19321 tagaagaagc aagaggaatt ttaaaattag atacagtttt tatgcgtagg ttagtgagca
    19381 caggcttgat aaaatcactg gctagaggtg atggtagaaa aatttcaaga tatgaagttg
    19441 atgattttat tgaaagaaat caaggtaaaa atttggatga acttttaaaa gcagcagaga
    19501 ggggggatga aattgttaag ccttaatact aataagaata atatagtaac tcttaaaaaa
    19561 gatggaaaag ttatagcaga catagtattt aaagatatta aaactggtaa gaaaatatcg
    19621 gttggagtat taaataaaaa agtgctggtc aaataaccaa cacacaaaaa aataaaaaat
    19681 aaaatataac acaaacaaat tatagcacaa aaagaatgga tttagaatag gtaatataac
    19741 attctaaaag gtttaatgtg taataattgt agcaatttag aatgtagctt atatagatag
    19801 taataaattg ggagggattt aaatggaagc agctagacta atagcaatag gtcaaattaa
    19861 acaagcagaa aaagaaatat gtaaattaca aggtacaaaa aataatagta gtttaatgtg
    19921 gtgggaagcc gtaaaatttg ctagtcaaaa tatattagag ggtcttgaac atgacattga
    19981 gttagaagct tctattgagt ttagagaagc tatgatgtat caagaagaac ttgaaaaaga
    20041 tagaccaata gatgtccaga tataaaaaaa gagccttcgc acaggctcta agtgaaaata
    20101 agttacaaaa attataggta tattataaca taagggggaa taaatgaaaa caaaaaatga
    20161 aataattaag gatttagaag atagattatt tttattaaga tttacaacag tagatgaagt
    20221 agattgggat gtaaaatttg gacaaatatc agcattagaa ttttgtatag ataaacatag
    20281 aaaaggatgc actttgcaac aattcaaaga aaatttagaa gaatacaaat tacaagggaa
    20341 ctatggtgat tatatagatg gttttgtgtc agttttagaa agaaatatta gagaaatgga
    20401 gggagaaatt gatggaagtg aataatattt acataaaatt gatggatgta agaattaagt
    20461 ttaacaaatt agatataaaa aagagtggtc aaaacaagtt tgctaacttt aaatattttg
    20521 agttagcaga cttcttacct caagcaacag agctgttaca agaagctaaa ttatgcccta
    20581 tagtgacctt tacaaatgat tatgcaactc taacattgat taatggagag aaaccaacag
    20641 aagagataat atttacttct ccaatgagag aattacaatt aaaaggctct aatgagttac
    20701 aagcattagg aggaattgaa acatatcaga caaggtattt gtacattcag ttattaaaca
    20761 ttacagaaaa tgatactttt gatgctacta gtggaaaaga agattataaa agaaatgact
    20821 taacaaactc ctctattaaa gcaagtgaaa atggtcaaat aaaaataagt caaaatcaaa
    20881 taaaaagatt gttttcaata ggaaatacaa taggcaaaga ttcagataga gtaaaaagtg
    20941 aagtgtatta taagtttaat aaagaagtta aagatttaag taaacaggaa tatgaccaga
    21001 tatgtgttgg atatgagaaa ttgcaaagag aaaaagggat aattaagtag gtgaatctct
    21061 tgaataatat ggacaaagtt attatagaaa aaggaaatat attaagtgat gggtatggtc
    21121 ttatgccaag gttagtagca agagatagat ggttaactgt tggtgctaga atgctatatt
    21181 cttatttatc cagttttgca gggataaatg gaacttgctt tccaactaga gatttaattt
    21241 gttatgagtt gaatatatca aaagatacat ttacaaaata caaaaatgaa ttggaactta
    21301 gtggatatat aaagattcat aaaaataaat ctaaacaagg taaaatgcaa aataatatat
    21361 atgaaatagt atttgataga acttatatag atgaatgtat atctagaaga ggtgtaaaag
    21421 taaataaaaa gaagaaaaaa ccatgtccta aaaatataga catggaacca tgtcctactt
    21481 ttccggacac gactcagccg gacacggaaa atgtggacac taatattaat agttttaata
    21541 ttaatagttt taatagtatg tatatagata agcctgtgga taactattta aaagaattta
    21601 agaagctata tgaagaaaat ataggagtag tatatccagt cacagctgaa tggttattag
    21661 aagtatctaa ggaagtagat ataagagtat ttaaaagagc tatagagata tgtgctgaaa
    21721 gaatgaatat gaatttatca tacttaaaag gaatccttaa aaagtggaag gatgcaaata
    21781 taactacata tgaacaatta gagtcatata aattacaaca tgaaaataaa aagtcaaaaa
    21841 aacctaatag tgtagtaagc aaaaataagt ttgctaattt tgaacaaaca tttactcaat
    21901 acagtaacaa agaattagat gaaattataa agaaaagcca aaaggctaaa tttaaataat
    21961 attgatggag gtattaaaat gaatcaagtt gtattagttg gaagattaac tagagaccca
    22021 gaactcaaat acataccagg gacaggtaca gcagtagcat catttacaat agctgtagac
    22081 agaaattata taaataaaga aggaaaaaga gatactgact ttataccaat agaagtaata
    22141 ggtaaatctg ctgaatactg tgcaaattac ataacaaaag ggaagctagt agcattagaa
    22201 gggaatataa gagttgacaa ttatcaaact caatcaggtg aaaaaagaac atttacaaaa
    22261 gtcagtacaa aatcagtaca atcattagaa agcaagagta aatcgagtaa ttcatataaa
    22321 gagagtgtac aagatggaac cataggacta gaccctcaag gatttgaaat tatagatgat
    22381 gatgagttac cattttaatc tgaaaattta aatatgaggt gaaataaatg tttaaagtag
    22441 aaaggtattt tagtggctca gtagtggaca accttattga agatgacctt acatgtagaa
    22501 actacttagc attatattgt tgtttgttgg gaattacaaa aaatggaaaa aagatatatc
    22561 ctaagccaga aaaaatgtta gctgagtttg gagtaaagaa ggacagaaaa ataaaaaaag
    22621 agttaccagt aagaattaga aatgttaata caggggaagt aaaagaattt gagtctatgg
    22681 atggtgcagc ctgtttttta aggttaaaat atcaagcagt ttatcaagct attaaaaaga
    22741 aaactaaaac aagaagtggc tggaaagttg aatatattaa ggaggaataa tggaagtttc
    22801 aaggacagaa tatacaatta aaagggcaaa agagttatat gacaatggag aggatatatt
    22861 tattgctata gataaggcta gagaagaata tgaggagatg attaaaagtg aatatcttag
    22921 ctagtgtaat attagtaata ggaagtttta tagctggtag agtttatgag tatagattga
    22981 atctaaaaga gtgtgaaaat tgtaataaca aatatcctga aaaatgagaa agaagtggtt
    23041 ttatgaataa aagaataatt tgcaattggt gtggtaaatt attttacatc ccaaaacagt
    23101 ctaaaaaaat ttactgttgt aaaagatgtg agagaaaggc taatagaagt aatagagaac
    23161 agcaaaatta attttaaaca ataacactat gggggaatag caatgaataa gtttcaaaaa
    23221 gcagtttctc aaatggtaaa gcaagaggaa aaagagaatt tatggcaagg atatgaaaat
    23281 tgtagagtag gtagaagtat atcaagttcc ataagaagat atgtaaaagg gtttaaaaag
    23341 tttggatata gtgtacatga ggtttatgaa tttataaacg atattaataa gtatgagtaa
    23401 ctttaagtga taaaggaagt atttgattga gtaaatacaa taataagaaa attgtaatag
    23461 atggaattaa atttgatagt aaagatgagt cagagtatta tttatattta aaagaaaaaa
    23521 aggaaaatgg agaaataaaa gactttggac ttcaacaaaa gtttgaacta caacctaaat
    23581 ttaaaaaaga tgggaaaagc tatagagcta ttacatatac agttgatttt gccatataca
    23641 aatggaatgg tgaagtcgtt tatatagatg tgaaagggta tagtacacag cagggtgaac
    23701 ttagaaaaaa gctttttgac tataaatatc aggacaaaaa attgatatgg attgctaaaa
    23761 gcaaaaaata tggggtagat ggttggatag aatatagtga acttaagaaa aagagaaaag
    23821 aaaataagaa aaaggtagct taaataaata ggagtgatgt tatggcaagt aaagttaaaa
    23881 aggagttttt tatggcaact aaaaaacacc ttgagaacta caaacaacta catattaata
    23941 ttgaaagtct aaaacttcaa ataaaaaatc tcaaagagtt ccatttaggt gattttatgc
    24001 aaggtttaag ctatgacagc attcccataa gtaagactaa ttcaataagt aatcaagttg
    24061 aaaatgagtt aattaatctt gaagaaaaga taatagaaaa acagatagaa ctatatgaaa
    24121 tggaagcact aaaatataca atagatgtat ccataagcaa tttaaagcct atacataaac
    24181 aaattataag gtataggtat attgaaggct tagaatggag tttaatagtt gataaagtat
    24241 acttagaaga aagacaatta agagaaagag ctaatcaagc cattagttca atatcaatag
    24301 ccttgtttgg aaagaaagca ctaatagagc aagaaccatt atttaagatg ttagatttat
    24361 aggcagtgaa tagctgtcta ttttttttac taaaaaaagg aaaaaaggta ttgattatat
    24421 cggtacgaca tgatataata taaatataga aaggaggtga aagaagtggt caaaaaaata
    24481 aaagagttcg gcaaagttgt caaagccctt accgaacttg ctcttgaaat aggtacacta
    24541 atagccgtta taaaaatggt attagatagc ctataagact ttagaagggg agtcagcacc
    24601 ttcccttcta attaaataat aatacatgac cactcaaaat acaatgggaa aatataagga
    24661 attaattaca gaattaggga aattaagttt tggtatagtt aaattaattg gtgcaatagc
    24721 attattaata tttgctataa aatatttatt ttcctagagg gagagaaaga aatggaaaaa
    24781 agaatattga aagtactctt atcaaaaagt ggctctggtt cactaagtcc taaaataagt
    24841 ctacctgcaa catggattaa agaaatgaat ataacacaag aagagagaga agttgaagtt
    24901 tattttgaaa ataatgaaat taggattaaa aagaaagacc tagattaaat tctaggtctt
    24961 tttattgccg tttttctgcc gattttacaa tttaaaatgt gagataatag tattgtggaa
    25021 atgaatattt ctctctcaaa actaaatata tgtgggctag gtaaagggat tcacctagct
    25081 tatatgagca gactaggcag ggcatgagga tgctgtaagt tcaattctta ctatgttcaa
    25141 acttattaat acactatatg tagatatgct ggattaaaac ggaatttaat tcaaatgtct
    25201 aaaagagtgg ggcttggtaa cctcactcaa tttgcaagga ctggtgtgta atcttaggtt
    25261 cgattcctaa aacttgctcc cttaaatata atatgtatcc cctaagaata aggctttaga
    25321 ttaaatttaa agtcttattt ttttatttat aaagcaaata aagaggtggt ggtatggcag
    25381 atttgactga aaaacaaaaa aggttctgtg attattatat tgaaactggt aatgcaacag
    25441 aagcatacaa gaaagcatac aaaaataaca atcaaagaac atcagaaagt aatggaagta
    25501 gactgctgag taatgataag gttaaaaatt acattgatga aagattaaag caaattgaat
    25561 caaagaggat agcagatgca aaagaagtta tggagtattt aacaaagata ctaagaaatc
    25621 aagaacaaga agaagttgta atagtatcag aaaatggtcc tgaaataata aaaaaagatg
    25681 taagtataaa agatagaaat aaggcagctg aattattggg taaaaggtat gctttatgga
    25741 ctgaaaaagt tgatttagat ggaaatgttg gtgtaactat aattgatgat gtaggtaatt
    25801 taaatgatgg atagaaaaat atctgaaata ataaataaaa atttttatga attttggaaa
    25861 gtaagtaata gtaacaaata cctatatcat gtattaaaag gtggaagagc ttcagctaag
    25921 tcaacacata tagccttttg gttaactatg gctatggtta aatatccagt aaatactgtt
    25981 tgttttagga aagttggtaa tacaataatg gatagtgtat atgagcaatt gaaagaaact
    26041 atagaaatat ttggtttaac acatttattt cagtttaaaa aatccccaat ggaaattatt
    26101 tttattccaa gaggaaataa gtttatattt agagggcttg atgacccaca aaagataaaa
    26161 tctataaaat cagctaagta tccaatagct tttgcatggt ttgaagaggt tgcagaaata
    26221 aaaacagagg atgagttatc tatggtaatt aactcagtgt tacgtggaga attaccagac
    26281 aaattgaatt ataaaatatt cttatcatac aatcctccaa aaagaaaaca atcatgggtt
    26341 aataagaaat ttgaaacaca tgtattacct aaaaatacat atgttcatca tagtatttat
    26401 ttagataatc ctcatatatc aaaggctttc attgaagaag ctaatgaaat taaaataaga
    26461 aatgagttta aatatagatg ggagtactta ggagagccaa ttggttctgg agtagtccct
    26521 ttttctaatt tagagtttaa aacaatcaca aatgaagaaa tattccagtt tgacaacata
    26581 aggcaaggta atgactttgg atatgcaaca gaccctatgg catttgtaag actgcattat
    26641 gacaaaaaga aaagagttat atattttata gatgaaatat ttggggtgaa aatgtctata
    26701 agagaattag cttctaagat taaatcaaaa ggatatgatg actttagtgt tatttgtgac
    26761 agtgcagaac caagaagtat tgcagagctt agagaatatg gaataaaagc attgaaggct
    26821 aaaaaaggac ctggttcaat cgaatttgga gagaactggc tggatgattt acaagcaata
    26881 gtaatagacc caaacagaac tccaaatata gctagagaat ttgaaaatat agattatcaa
    26941 acagataagg atggaaatgt aagagctaag ttagaagata aagacaatca ttcaattgat
    27001 gcaacaaggt atgcattaga gttagatatg aaaacacatg gaagagaaag aaaatataac
    27061 agtagatagg gggtgtaaca tgttagattt gatagatata attcagatgg aacttacagg
    27121 attgtatggt caagaagtaa taagagaaat gggtgaaatt ataaggctat atgataagta
    27181 tgaaggtaca ggacaacatt ggatagaaga ggaacaagat tataaacaaa caaggaagaa
    27241 aacaaattat attaaaaagc tgattaaaga agaagctaga tttttatttg gtaagacacc
    27301 aatatttaca ataaaaccag agaatgattt agataaagat aaggcagaag aaataaacca
    27361 gtgtattaat aagattctaa agaaaaattt gttttcagat aaactaatta aagcggctag
    27421 agattgtttt attggtaaaa gaatagctat aaagctacat gcagataaag aaagtaagag
    27481 tttaaagata atgtttgtac caagtttaga gtttatatat gaaccatttg ataaccaatt
    27541 tgatgagctc aagaaaatcg tatttttcca tcaaacaaat caagaagttg aaaaagataa
    27601 acagagaatt tggaaacaaa aatatgaaat ggttaatggt aaatgtatat taagtgaagg
    27661 tatttataat ggttatgggt tatgtataga agaaatagtg agtgatacag atttaaaact
    27721 tagtggaata ccttgttatg taattcttaa tgatggtttg cttggtgatt taaagggtga
    27781 gagtgacata gaagagatat ttgataatca gatggcttat aataagctag cttctgagga
    27841 tatagatact cttaaaaaag gaatgaatcg tatcatatat ggtgttgatg ttgaagaaga
    27901 gtcaagtaag cattttaaaa taaaaccagg agcttattgg gatgtagaaa cttctcaaac
    27961 ggctgaccaa aaacaagcac agattaatac aattcctact gactttggat atgatactag
    28021 aatagaaaac tctcttaata gaattaaatc agatatgcat gaagtactaa atatacctct
    28081 tataaataat caggacctta aaggtatgat gacatcaggt aaatcaatga aagctttgta
    28141 ttggcaatta ataactagat gtgaggaaaa aatgaaatca tggggtccag ctcttgaatg
    28201 gttgatacaa gccatgatag agatgataga agtatataat atagtaaaaa tacctatatt
    28261 agacaaagat tcttatgaag taattgttga aaatcaatat ccattacaag aagatgagga
    28321 ttcagaaaaa ttacttgata ttcaacaagt aaatgctcaa gcaatgtcta ggaagacttt
    28381 cattaagaag tggaataata gtaatgatga tatagcagat gaagaactgc aacaaatatc
    28441 aattgaaaga caaatattag aagaaagttt taatttggaa gaggaaacag aagctataga
    28501 tacagaagaa tcagacgaag taactaatga aaaagaatca aaagaagtag ttgatgatga
    28561 ataatggcta ataagtttaa taaggctatg aagaatgctg aaagagctag agacatatta
    28621 tcaaatagaa ctactaaaaa gataagaaag ttatataaag atatagctaa tgaatatgca
    28681 aaaaaattaa atagagttaa ctctaacaca ttaactgaac aatatttaag agaaagtata
    28741 atttatttaa ataaagagta tgataggtta ggaaagaagc taaaaaaaga tattgaaagt
    28801 gaaatatcaa aagtaataaa aactactaca gatgaacaat taagtttttt caataacata
    28861 tgtgataact attcagttaa tttaaagcca caattcactg atatgtttag taaagttcat
    28921 gaagatgtac taaggcaagt tatatctggt agcatgtaca aagacaaact taaattaagt
    28981 gatagaattt ggagtaatat agataaaact aagaaggatt tagactacat tgtaagtaga
    29041 ggattagcag aaaaaagagg tagttatgat atagcaaaag atttagaaaa gtatgttaat
    29101 ccaaaggtta agaaagatta tgattggtca aaggtatacc ctaaaagtaa taaaaaaata
    29161 gattttaatg cctatagact ggcatctaca tatataactc atgcatatca aaagacagct
    29221 aaagaaagtt gtaagaagaa tccatttgtt aaagggatta aatggatgtc atcacatcat
    29281 cctaggatgt gtaaggtttg tgcagataga aatggaaaaa catatattcc agaagagtta
    29341 ccattagagc atcctttagg aaagtgtact tttgaatatg atattccaat gagtatggag
    29401 gacataggta aagagttaag aagctggata gatggagaag aaaactctaa gcttgatgaa
    29461 tggtttgatg aatatggatt agactttgca ggaatagaag gaaaagctaa taagaataaa
    29521 gaaccaactg aagatgaaat gttagcttta tataaatata tgggtggaga tgcctataaa
    29581 attaatgaga aattaagaag aaatattaaa ttgacagaag aagatgaatg gtttataaat
    29641 aacttagata gagttttaga taaaatgcca aattatgaag gggatgttac aaggtcatta
    29701 tatttttata ataaagaaag tttaaaagct tttttaattg aacatgaaat tggaaaaact
    29761 atacaatact cagaatttat ctcgactaca aaaggaaaaa cctacaatcc agagggtcaa
    29821 gtagaaatat atatattcaa ttctaagaat ggtaaaaata taagtatgta caatgaaaaa
    29881 gaagaagaag ttttgtatag aagaaattct aaatttgaaa taattgagtt agaagaaatg
    29941 aatggcaaat attatatatt aatggaggaa cgcaatggat aataaatttg aagatgataa
    30001 gtattcagaa ccatttagtc atccaagatg gaaagatgta ccatggggtg aaactatagg
    30061 atatagagac attccagaag aagaaagaaa aaaatataaa aaaatactta gagaacatct
    30121 aaaagatatt ggagtattaa aagaagatta aagacactta cttaaattaa agattcgtaa
    30181 gtatgtacaa gttgggggag atagttacta attatgacta tacttcaaca acaaaaggaa
    30241 gtacttataa ttctgagggt caagtgcaga tgtatatatt aaattcacaa aaaggaaaag
    30301 atgtaagtaa atataaccct aaagaacaag aagtattata taaacgaggt tcaatgttta
    30361 aagttattga aattgaaaga attaagggaa caattcatat tttattagag gaagtgtatt
    30421 aaatgctaac aatagaagaa tttataaagc tacctgatga agaaaaagga gatgcttata
    30481 aagaattatc tcctcatgat atgtttttat ggagaacaca atattcacca attggatttg
    30541 aagtgatagg tcatgaagaa atctcagaag aagataggat taagaacaaa aagaagttta
    30601 gagaacatct caagaaaata ggtgtaatgg aagagtaaat atttataata gtcagaggag
    30661 ctataaaatg tgtaataaat ttgaagatga taagtactta gaacctttca gccatccaag
    30721 atggaaagac attccgtggg gggagactat tagggaagta gagcgaactg aagaggaaca
    30781 agcacaaata agaacaaaat ttagaaagaa attaaaagaa attggagtaa taaaagaaga
    30841 ttaaggcact tactgaaatt aaaaattagt aggtgttttt ttattgcctt ttttagctat
    30901 atataggcgt aaaagaaaca aatagcaaac tatactagag aagcaaaact cgtataaaag
    30961 cgtagtgtag gagggaataa tggaagaatt attaaaaaaa ttgggatacc aggacacaga
    31021 cataaaaaat ataattgagg gtatgaaaaa agataaaatt tacacttcta aggaagaaaa
    31081 tatagatgaa agatacaata agttgaaaga acaaaaatta gccttagaag agcaaataaa
    31141 aggtgcaaat gatactatat cagatttgaa gaaaaatagt aaaaacagtg aagatataga
    31201 ggcaaaagtg aaagaatggg aaaataaata taatgaactt gatagtacga gtagagctaa
    31261 aataaagaat atgactatag actatgctat aaattctaaa ctatctggag taaatgaaaa
    31321 atataggaag ctactatgta aagaatttga taccagtaaa atggaagtaa aagatactgg
    31381 agaaattata ggattagatg aacaatttaa agacatatca gaaacatata aagaatggtt
    31441 tgaaagttct actccaagta atacaggttc tccagggaat ttcccaagaa aatcaaatgt
    31501 agtcaataat ccttttataa aagaaacatt caatttaaca gaacaaggaa gattattaaa
    31561 agaaaaccct gataaagcta aagaatttgc agctcaagca ggaataaatt tataaggaag
    31621 agagtgattt aaatggcagt aacaaaatta agtgatgtaa tagtaccaga attgtttaac
    31681 ccatatgtaa taaacaaaag catggagtta tcagctctat atcaaagtgg aataattaca
    31741 aatgatgcaa gcttaaatgc tttagcttct caagctgcac cagttgtaaa tatgcctttc
    31801 tttgaggatt taagtggaga atcagagcaa ataatagaag atgctgattt aacaccaaat
    31861 aaaattactt caagtcaaga tgcagcagct atattaagaa gagcaaaaat gtgggcagct
    31921 actgatttat cagcagctat ggcaggaaaa gacccaatgg cagcaatagc tagtttagtt
    31981 ggaagcttct gggctagaga tatgcaaaaa gaacttatag cagttttaaa tggtgtattt
    32041 ttagctgcaa atatgacaac aaataagtta gatatatcag caggaacagg aaatgcagca
    32101 aaatggtcac catcagcttt tatagatgca caacagttat taggagatgc acaaggtcag
    32161 ttaaaggcta tagcaatgca ttcagctaca aaatcagcac ttaaaaaaca aaatttaata
    32221 gaaactatta gaccagatgt aggtccagat tttgaagttt atcaagataa attagttata
    32281 gttgatgatg gttgtcctgt atctaaagaa ggagtttata cttcttatct atttggtagt
    32341 ggggcaatag ctttaggaaa tggtaatcca gtagggtttg ttgctacaga aatagataga
    32401 gataagaaaa aaggttctgg agtagattat ttaatcaata gaaaaacata tatactacat
    32461 ccaagaggta taaaatttac taatgcaagt gtagctaaaa cagaaggtcc ttcaagatta
    32521 gagttagcaa aaggtgaaaa ctggacaaga gtttatgagc ctaagcaaat aagaatagtt
    32581 gaatttaagc ataagttata aaatatagtt tttagtaggt gatagtatgg atttagaaat
    32641 cttaaaaaat ataaaaacag aacttagaga agaacaatca cctttttttt ctgatgatga
    32701 aattacttat tactacaata aaaacaatca agattttaat aaaactatgt atgaactatg
    32761 tatattaaaa gctgaaaatg atagtatcac tttacctgga ggcttaagca tgccagaaaa
    32821 taaactatat tggttaactc tagcaaaaaa gtttaaaaca aatggaagta gatgtctatg
    32881 atagctcaaa aggtaaaacc aaagataatc aaagctatca ataagatgcc aacagaagct
    32941 atagtaaaaa gagttggagt aaatgagttt ggagagcctt cagatgaaga aaatatagtt
    33001 tgtaatgtga taggtttata tcatgaagga agtagctcta taagtcaaat aacaaaggat
    33061 aaaggtattg ttataaaaga taaggagcag tatttaatgg ttgtttgtga tgaagataca
    33121 gtaaagataa agcaaggtga ttttatgtat ttagataata ataagtttat tatacaagac
    33181 cttggaaatc aaaacagaat gaatatttat tttgatttaa agttaggaaa ggtgagatag
    33241 tatgagtaaa ggatttaaat ttgatactag caagctgctt aatgctttag taagtagaga
    33301 aatgaaaact aaggctgcac taggagctta tgcagacact tcatctcaac tattagaaag
    33361 cactgccaaa aacgatagac catggaaaga ccatactcat gatgctaaaa ataggctaca
    33421 tggtagttgg gaatggcaag gagatactat aaggatagca cttagtcatg gagttgacta
    33481 tggattatac ttagaaaaag gtacaggtcc acatgttata gaagcaagac ctggaagtta
    33541 tttattttgg gatggagcat cacattctgt taaaaaagtt aatcatccag gaagtagacc
    33601 atatccaatt ataatgccaa ctatagaaaa atgtgcacca agtattataa gaggtcttga
    33661 tgtgatttta aagtaggtga agtatgttta aaaaaatata taaacattta aaaaataagg
    33721 gttttaatgt gtattctatt ggacaacatc aaggattatg catagaacct tttttagtta
    33781 tatttgaaaa aggtcctcta caaacaacag aaaaaaatat aataaaagat ttatttgaaa
    33841 tatatgtatt ttatccaatt ggacagtatt ctaaagtaag tgaatacaag ataagtgttg
    33901 aaagtgtcat ggatgaaata gtaggaataa aacaagctta tgaagcttta cctattctta
    33961 tagatgatga aaaacaagct tatttcacaa gattaagtta ttatgaaaac aaacaaatta
    34021 ggaggtaata aatatggcag tacaaatatt aaatcaatac ccacttacag atgttgtatt
    34081 agttcaaatt gaaacagttg aacaaaatcc ggttacatat acatttgata catctgatga
    34141 gatagggaca gaggaaatca tttctgaagg tgaagaatta actttaaaaa taaagaaaaa
    34201 aataatagca aatagagcag cagaagatac aagtttagga tatgatttga cattaaaaga
    34261 taatgtattt tgtcctgaaa tacttcaaat aatgcaaggt ggaacaatag aaaaagagga
    34321 agatggtagc tttaagagat atttagctcc agaagtaggg aagacttttt ctaagaaatc
    34381 ttttaaaaca ataatttata gttcagttgt tggaccagga ggagatactg ggcaatttgc
    34441 taagacgact ttcccaaatt gtaaaggaaa atctgttcca ctaaacttta aagatggaga
    34501 atattattca aatgaatatg ttataaatag tagacctaac acagggcaat ctccttatga
    34561 ggttgaaata gtagaggaat tacctaatgg ttatgaagct acaaaagtat ttttagacag
    34621 tgcatctgta tcaggagcaa cagctggaga taaaaagata acaggattaa cagcaggcaa
    34681 aatatataag gttacagtta atagcaatat aaaatatact ttagcagatg gaacattaac
    34741 agatactgag tctgataaag cagcattaac aggaacagag ataataggat taacaaatgg
    34801 agaaacatat aaggttgaag aagttagtat aagtatataa atagatagat taaagctcta
    34861 gtaattagct agagcttttt tagaaagggg acataaatat gaatgaactt aaagtaacaa
    34921 gtttagaaga attaaagaaa ataaaattga ctgaggtaat tgaggttgga agatttttag
    34981 atggaactat gttagttgca gaagtaaaac aacctgactt aatggctctt gcaatggctg
    35041 gtaagatacc aaacagccta atgacagcat caatgagttt agttgaagag aaggaaagta
    35101 aagatagtac aggagaaaaa gtactaaaga agatgaatga tgagtctaat ttctcaaaag
    35161 aaatgtttga aatgatggat atagtggcta aagaagtgct agttaaccct acatatgctc
    35221 aaattaaaaa aataggattg gaactttcta ttgaacaaag attaacattg tttaatcgta
    35281 ttcaaggagg tacaaagtca ctagaaaact ttcatcaaga gtccacagat attgaggatt
    35341 ctaaatcaag tgataatata caacaagatg cctagtgaga tattaagaat taaagatgaa
    35401 tatacttctt tttgtttcga tgaagcttgt atgtttttag tagatgctat aaaaaatgat
    35461 aaaaagctta aatttgaaaa taatgaaaag aaaactatag ataaaaatga gagaaaaact
    35521 tttgtccaaa tagcattaga gaaaaagaaa aaagttaata ggtaaaatat tctaaatgaa
    35581 tagagtgaat taatgttaat ttatgatata atgataatat agatattttg cagtgtctga
    35641 ttttttatat acattggatg taatcattga aattactgcg atataagcat attttgtgat
    35701 gtgcgaaaaa cactactggt tacttaatgc aattttaata tggttttata tgtgcaagaa
    35761 ctggaagtgc tcaatttatt ttggggtatt atattaacta tgtggtatgt aaagaaactt
    35821 acacgggaca atgtaggtca agttgcaagg tattatatta actatgtggt atgtaaagcc
    35881 aatctaaaaa acctgttttt atgctttccc accatgtatt atattaacta agtggtatgt
    35941 aaaggaaatt ataactaata ttttaagtaa tgtacagggg agtattatat taactaagtg
    36001 gtatgtaaaa attgttttaa attgattaag tacatctgtt gcatttatat tatattaatt
    36061 atgtattata caattaaatt aaaaaatata tttgagttag agagggagta ttttatgtcg
    36121 ttatttggaa gtaaaattac aaaagaagaa aaagagaaaa atcgagaaga aactgaaaag
    36181 cattatgaaa gacttaaaaa tatgacaaaa gaagaaaaaa aagagtatga aattcaagag
    36241 tttatgaaga aatatcaatt agaaaattta gatgaaaaag atttaatagt gttaaagaga
    36301 atagcaagtg atttgtttgg aaatggtctt attaaggcag gtatggcttt aagttttact
    36361 gatgcaaagg aacaagcaaa aataggatac cttagcgctt taacagaaca aaattggatg
    36421 ataattagac agttagctca gttgaatacc aatatagaaa aacttataga agataaaaaa
    36481 gaataaattg aaaatagcaa tacagacact tacttaaata gtaggtgttt ttttatgtgg
    36541 aattttgagg aagggaggga aaaatatgtc tttagaattg ggaacagcag taggttatct
    36601 agatttagat ggaggaaagt tttttaaagc tcttgctgat gcagctaaac aacttagtca
    36661 atttaattca cacactaagt ctactggtag tgctatgaca gcaatgggaa aacaaatttc
    36721 tgatacagca agttctttga cacaaatagg tagacaatca gcattagcag catcagaatt
    36781 aaataaaata gcatcaactt caagtggacc attttcatca ctaaaaaact ctataaaaca
    36841 gactgagaat gaactaaaaa cagcaagaag tacaattgat gcatatgcac aaggtatatc
    36901 taaacttaca agtgaaatag ataagtcaaa gcaaaagtac actgaaatag gaagtaaaat
    36961 agaaagatat gagcaacaat tagaacgttg taatagtatg tatggagaaa gttcagagca
    37021 gtcacaaaga tatagagaag ctattgaaag acttaaaaat tctcaaactc agttaggcaa
    37081 tgaaatcgaa aatggagaag attctttaac tgatatgaga acagctatga ataatgcaga
    37141 ggcagaagcc aatagattaa gtgatagttt aagtagtatg ccatttgatg ctattggtgg
    37201 caaaatgaga gatattgggc aaacactgac ttctatagtc acaactggac tagttgcaat
    37261 gggaacagca gcagtaacag cagcaacaag tactgaacaa gcaatgtcag ttgttaactc
    37321 tatactacaa cttaatacag aaaaggttca aggtggtaaa agtgaatggg atgcttatgc
    37381 aagtacatta aaagaaggtg ctaacgaaat tggaatggct tatgatgaat atgccaattc
    37441 tgcctataat gccatatctg caagtgtaaa acaagcagat gtaacagaat ttttagcaca
    37501 agcagataaa ctagcaacag caggtttaac agatttagca aaagctacag atgtgttgac
    37561 aactattcaa aatgcatatg gtatgtctca aaaggatatg gctcatgtaa gtgatgtact
    37621 tatacaggtt caaaataagg gtaagattac ggtggatgag ttagcaaatt ctatgggtaa
    37681 aataattcca actgcaaaaa gtttgaatgt atcagttgag caactaggag ctggatatgc
    37741 tatattaact gcaaaaggaa ttgctggcgc agaagccaca acgtatatga atgcgatgct
    37801 caatgaactt gggaaaagtg ggagtaaagc agataaaata cttaaaaaat taacagataa
    37861 aggatttgct gatttacaaa aagaaggtaa atcaacagca gatgttttat taatattaaa
    37921 tgattatgca aagaaaaata gcttatctct atcagaccta tttggttcag cagaaggtgc
    37981 aaaggcagct aatgttttac taggtgatgc agttaatgaa actacaggag aaataattga
    38041 aggtacaaag agtgctgatt catttaatca aatgcttaat gatatgaaaa attctactgg
    38101 actttgtgat aaagcgtttg agcaactgga taatactaca aagactaaac ttgaagatgc
    38161 actcaattca gcaaagaata tgttatctga cttaggtgaa gttatgatgc ctgtggttgc
    38221 taaagtggct gaaatggcaa ctgcttttat gaaaagtgtc agcgaaatgg caaagagtaa
    38281 tcctaatttt gctagaataa ttgtatcaat aggagctgta gtcgcagcaa taggaccttt
    38341 attagtagtc cttgggacaa tggcaatcac aatacctaag gccatttctg caatcggtac
    38401 agcaggaaaa gcatttacat ttctatctac aagttttgct attgcaagaa aaacaataac
    38461 gtctacaagt gcaggagcaa gtgcaggaat gataaaaatg tctaaagtaa tggcaggatt
    38521 aatgggcccc atgggtttag tagtagctgg gatagtagct ttaggagtgg cttttgtagc
    38581 tttgaataaa cacatgtcac aagactcaat tcaagtttca gaaaggtttg gaaagaatat
    38641 atcagatggg acacaaaaag cagttggagc ttttatggat ttagaagagc aaacaacaac
    38701 tactttaaat cagatgttgt ggtctggaga aactgtttca actgaaatga aggatacttt
    38761 aataagtaac tttgattcta tgtctagtca aataacctca aagttgaacg aaacgaaaga
    38821 aagtagtcag gctacattgc aggagatgtt tgctagctca actactttat cagataaaga
    38881 aaaagaagct ttaataaaaa atacagatga agcttatagt aacaaagaaa agaaagtaga
    38941 agaaagtaca gctagagtaa aagaaatttt aactaaagca agtgaagaaa atagaagtct
    39001 gacacaatct gaagcagatg aaataaatcg tattaaaaca gaaatgttaa atacagctgt
    39061 aaatgtcatg tctgaaagtg aagcagaaca agcagcgata atggaaagaa tgagagctaa
    39121 tgctacaaat ctctcagcaa aacaagcagc agatgttgtg aaaaattcta taaagcaaag
    39181 agatgaaact gtaaaatcag caaatgaaga gtacaatgag aggctcaagt tagcagctca
    39241 acttagagct gaaggtggaa aagaaaatga agaacttgca aataaagtaa ttcaagaagc
    39301 tacaaaacaa aaagatgaag cagtaaaaaa agcacaagaa atgcacaaag aaattgtttc
    39361 agaagctcaa aaacaagcag aaggtcaagt ggaaaaaatt gattggacga caggagaaat
    39421 aaaatcgaga tgggaagtat taagagatga aatcaagaag aatattgata catctcaaag
    39481 cgattttgac acttggtgta gtaatacaga caaaggattt gctgatacgt ggaacaaaat
    39541 aactcaagga gtttcaaatg cttggaatgg tataacagag agtttgtcaa atgcttggaa
    39601 tagtataaag gaaggttgta ataacctttg ggcaagtata tctgaaggtg ttagtaatgc
    39661 gtggaatagc attttagaat ggacaacaac tatatggagt aatataacaa gttttttagg
    39721 cgagttatgg gaaagtatta aagaaatggc tataaatgca tggaatggta ttgttagttc
    39781 agtaacagat gcatggaata gtataacaga attcttaagt ccagttacct cattcattag
    39841 cgaaatggta aaaatggcat gggaatcaat taaagaaaca gctataacta tttggcagtc
    39901 tatttctgat ataatacaaa gtgtttggga ttttataaag tcgattgtgg gtcttggcgt
    39961 ggaaatagta aaagcattaa taagagctgc gtggcaaggc ataaaagata taacttcatc
    40021 gatatgggaa ggcataaaaa gtgtaataca aagcgtttgg gatgcaataa aaccatatgt
    40081 aatgggtgca gtagatgctg taaaaacagt tgtaacaaat gcatggaata gcataaagga
    40141 tatatcaagt acaatttgga atggaattaa gacagttgta acaaacgcat ggaatggaat
    40201 aaaatcaatt gctagtggtg tgtcgaatgc ggtcaagtcg gtagtgtcaa gtgcatggaa
    40261 tggaataaaa agtataacat cttcgatatg gaatggaatc aaaacagcag tatcaaatgc
    40321 atggaataat attaaatcaa gtgctacaag ttcagtatca aatgtaaaaa atacaacaac
    40381 atcaggattt aattccttaa aatcggcggt tacaactata tggaataata taaaaacagc
    40441 aatatcaaat gtatggagta atataaaaac agcagtaagt aatggtgcta atgcagtaaa
    40501 gtcagtatgt tcaagtgtat ttggtacaat atctaatatt ttaacagctc catttaaaac
    40561 cgcacaaaaa gccataagtg gtatacttgg aggaattaca aacaaaataa atggaataaa
    40621 agataaagta agtggacttt ttagaagtgg tcctatgatt cctcaaaata gtaacgattt
    40681 tattcaaaaa gatatgttac caacaccaat tatgttcaga acatcagttg caggttttgc
    40741 atcaagtaga ggaagtatac tagattctat tggtaaactt tctaatacta tgacgaaagg
    40801 aatgggtagt ccatcaggaa tgatttcaca atttggcaga gcaggagaaa attcagcaaa
    40861 agcatactta gatggattgt caaacataga agaaggatta acaaatacac ttagagcagt
    40921 ccaagcaata ataggtaatg gaaacataaa agaagctcaa gaaattaaaa agtttaataa
    40981 ggaagttcaa aagctacaag aagaaaaagc tgaagaaata gcagaattag ataaagaaca
    41041 taagaagaaa caaaaagaaa gaaatgaaaa agaaaatgaa gaaataaaag aagcagaagc
    41101 aaagaaatat aagaacaaaa aagaaaaact agcagcatta aagaagatta aagataaata
    41161 taataaggaa tctgtaaaag accaagaaga atacagagaa aagttggaaa aaattaataa
    41221 aaagtataat aaaaaagaaa aagaggatac tgaaaagcat caagaagaac tacaaaaact
    41281 tagagaagaa aaaataaaag ctgaaagaga tttcaataaa aaatataatg atattaaaga
    41341 agattatgct gaaaaagtag caaacttaga taagaaatat attgaggacc aaaagaaact
    41401 caatgaagaa tatcaaaaga tatatgactc aagagtaaag tctttaatgg attatacaga
    41461 tttattttct tctgtaacat ttgaggaaat cgacaacgat gaattaatgg aaaacttaga
    41521 agagcaagtc gatgtactta gaaaatggga cactgatatg gcagatttat ctacaaaagt
    41581 aggtaaagat ttatatgagg aattattagc taaaggacca caagctcata atgagataga
    41641 agctatcaac aagatgtcaa aagagcaact agaagaatac gaaagattat atcaagaaaa
    41701 gaagaaaata gctgaaagaa gagccaaaga agatacagaa gatgaaaaat atagaataga
    41761 aaaagaaatt gaagaattga aaaaaactta tgatgcagag tatagaaaac taggtcaaga
    41821 aatgcaaaga agtatagagg aacaaattga aagttttaag gataaatttg gagtagtacc
    41881 agctatgttt atggaaacag gcaaagattc tatgcaaggt atgatagatg gtattaaatc
    41941 tatgcaagga gcattgggta aggttttaag tgacatagtt aattctataa ataaacaact
    42001 ttctaatata gggtttaaag atgtaaatat acctacagga ggaagaaaag aagtagcaag
    42061 gtttagaaat gaaatagaaa atttacaaag tatagcatat tcagatactc tggcaagagg
    42121 aatagcatca aataatttac tgaaggatgc aactgttaat ataaataata atagtaaagt
    42181 tgatagtgaa aaaagtagtg ataagaaagt tgagttaact ttacatatag aaaagtttat
    42241 aaataatact aaacaagata tagagcaatt aggttctgaa atagcattta ttacaaatag
    42301 aaaactaaag ttttaatgtg ataatatctt tttaatatcc aaattgtggt ataatacttt
    42361 tagcaagaag atgtaaccta taatctaaga gtggagttca tactgagata aaacctactt
    42421 tctaatgaaa ggaggtggta agtatgaaca actttttact taatgtaata gctggtgtta
    42481 ttgctagctt aatattttgc ttaataagta agatatttgc aaaagtaaaa agccactctg
    42541 tgcgaaagag tggctgggag tttgatttaa aaatcaaatt ccataaaaaa taattagctt
    42601 ttaattatga actccgctct actgacaata gattgtagtt cttcttgctt ttattatatc
    42661 acatcttagc aaaaatatgc aaagtaaata gaaggagatg tatcaaaaga aaaatttgag
    42721 tcatctcttt ttttatgtgt aggaggtgat aatttggctt tacaatactg tgtcagtgaa
    42781 aatgaattag tttcttttca atatggcgaa ataaatagta gagattttgg tattgtaatt
    42841 acagatatta atgaacttgc atcgccagaa cgtagatttg aaagaataga gataccagga
    42901 aggaatggga gtcttatttt agatgaaggt tgttatagta attttaatct tgaaatagaa
    42961 tgctatatag atgtagatgg taaagatatt aatatactag catctgaaat aaagatgtgg
    43021 ttacaaactg atttttcata taaaaatctt attataagta ctgacccaaa ctattataga
    43081 gaagcagttt gtattaacaa actagattta gaagaaatta taaaagattt aggatatttt
    43141 aagattacat ttgaatgtaa accacttaaa aaacaattag ttaataattt aattacaata
    43201 aatgaatcag attctaagct aataaacact ggaatggctt cgtatcctct tataaaagta
    43261 tttggaaatg gagatataac attagaaata aataatgagg tgatagaact tacagaagtt
    43321 caagggcata tatatattga ttgtgaactt atgaatgctt acaaaataga tattcataca
    43381 aatgatgtag ttaatgaaaa tagtaggatg tttggagatt ttccaacatt taaacatggt
    43441 gaaaatataa taacatactc tggagatgta gaaaaaatag agatagaacc tagatgggtg
    43501 gtgttataga ttgcttagat tatataaagc aaatgaaaca aattttaaaa ataatggttt
    43561 ggggattcta aaagatgcag ttgaaacaaa agttacagaa gaattaaatg gactatttga
    43621 gttagagttt acatattatg tgggctcttt tttatttgat gaaattgatt ataataaaat
    43681 agttatggct gatgcttctc caaggcttaa aaatcaatta tttaggattt actatatttc
    43741 taaggaactt gatggaaaaa tattaattaa agcagaacac attagttatg atttattaaa
    43801 taattttata gaaaatttag aacttaaaaa tgttacttgt gaagaagctc ttaatcaaat
    43861 atttaggtca tgtactgaag aaaatagatt tgtaggatat tcagatataa caggaaataa
    43921 agacttttca atctcttgtg taagcccaca taatgctata tctgacatac aagaattatt
    43981 taataataag tctaaactaa aaagagataa tttcaatata agtttattaa ataattttgg
    44041 agaaagtaac aatgtattac tagcatatag aaagaatata ataggtctaa cagctactta
    44101 tgatacacaa gaagttataa ctaagatata tccatatgca actaaaaaaa gtggtaaaaa
    44161 taaaaaaatt acactaccag aaaaatatat agaaagcaag tatataaaca attatccaac
    44221 tcaaagaatt gttgcagttg atttttcaga tgatgatgtt aagaatgaag aaagcttaag
    44281 gaataaatgt aaagactatt ttattgaaaa taatgttgat ttacctaaag ttacttacaa
    44341 agtagaattt gtagatttat caactacaga agattataaa agctataaga tgcttgaaac
    44401 tgtaaatatg gatgatgaga taatagttag agactataac ttaggtataa atgctactgc
    44461 aagggtagta aaaactgaat ataatccagt attaaagaaa tacaattcgg ttgaaattgg
    44521 tgacttagta aatcatttta aagacgaaag aatagatgat ttagaagaaa aaatagataa
    44581 ggttcaaaat aatgtagata atattgtaat tgaaagtgat aattttccgg atacacttcc
    44641 agagccttca aatgtcacag cattagggtt atggagtatg attcagttag attggacttt
    44701 tgataataag ttatattata actatgaagt atatgcatct caaataaaag gatttgaacc
    44761 agatactgca ggatatacaa ataggatata tgtgggtcaa gcaagttcat tacttcatga
    44821 agttaagcct atgcaaactt ggtattatag agtaagggca ggaaatacac atgataacta
    44881 taatgaattt tcaaatgaag ttagtgcaac aactagaaag ttaagtgatg cagctgaata
    44941 ttttgaagaa gcagctatag gtcatgcaat tataagagat ttagatgcag ataaaataaa
    45001 tgtaggaaaa gtaaaagggc agtatattga ggcaaagaat ttagttgtag ttgatggaaa
    45061 tagccagaca actttaaata tagatagttt tggaaatgtt catgtaggag caactacctt
    45121 tacattaaaa gggaagtcac tggaatctat tattggtgga gaaatagaca atataactca
    45181 acttgagata tttaataaac taactaacaa tggtcttgca aagggactct atatggttgg
    45241 gaatgaatta tatctaaatg ctagttatat aaaaactggt actttagaag gtcaatttat
    45301 aaatggtaga aatttaactg tcagagataa tgatggatat acaacgttac aagtagatag
    45361 taatggaaaa gtgaatataa gagctaatga gttatctata ggtgataaaa ataactatga
    45421 aagtgtttta actagtgacc aaaaagcagt atttgatgca ttaacaggga atcgaaattg
    45481 tggaatatat ttaagtggaa gtagattata tataaatgct gattatatag acacaggtac
    45541 tattttatgt gacagaatag gtgctagttc atcaaaccca ttcatattac tatttgaggg
    45601 gaatggtgca aaatgtgctt tagatgctac tgctcagttt ggagtaggta taggaaaagc
    45661 aatgcgtatg aaatataatg attattcata tatatatgtt tctgatgatg taattagtgg
    45721 ttatcttgat ggagaggaag tatttgaatt tggttatcaa gatgaaaaaa gttacattaa
    45781 tacaggtttg aatacacaac atataaatcc tcaaatagat ggttggtata attgtggttc
    45841 aaataggaaa gcttgggatt atttagtatg taataattta aatcaactag caagaacagc
    45901 agctacatct actcgaatga tgaagagtac atttaatgaa gaaatttcaa ataactgtat
    45961 agattttgtt aaaagtagct tagtacaatc tgatgtattc acaccatata atttaaaatc
    46021 tatgaaaaac aacaatattg aacatagact acaggttgat atagactcct ctttagataa
    46081 tcctatttct aagtacattt tcaaagatgt atcagatgaa gctggtgaag gtgtctatgc
    46141 acaagatata acatctcatt tagcagtatt acaattatct ttacaaaaaa ctatatcaaa
    46201 ttttgaaaat tataaagata taacaagtaa aaaaatagaa gaacttacaa aacgaataga
    46261 agtattagaa agcaggtgat ataacttgag agatagaatt tatattgtag atatcaacac
    46321 aaagatgtat caaatagcaa gatataagca aaatgataat aatgtatctt ataacatgag
    46381 aatagtacaa gactctatag atgttgattt aactggatat acagcattag cattttttaa
    46441 tttaccaagt ggaagagtta ctcagaaaaa ttgtactata gaagattcaa ctgtttatac
    46501 tgaattaagt catatagagc tttcagaaga aggagatgtt atttctgaga taactttata
    46561 taaagacgat aaggtagtta ctacgttttc tacaataata aaagttgaaa aaagtataaa
    46621 tagaaatgca atagaggatg agcctagctg ggatataata aaggacatat taaatgtatt
    46681 aagttatgaa gaagaaagac aagaaaatga aaatgtaaga aaatctaatg aagaaattag
    46741 aataagttct gaaaatgtta gaactggtaa tgagaatata aggattgaaa gcgaaaatca
    46801 gagaaaagat agtgaagttg aaagatgtga gagtgaagaa gtaagaaaaa cacaggaagt
    46861 tattagagaa gctaatgagg aaacaagaaa aacaagtgaa acaacaagag aagctaatga
    46921 ggaaataaga aacacaagtg aaataacaag agaagctaat gaagaaataa gaaaaacaaa
    46981 tgagatagtc agagagtcaa gtgaagaaac tagaaatact aatgaagaaa caagagaagt
    47041 ccatgagact gttagagaat caaatgagga aataagaaaa actagtgaag aaataagaga
    47101 atcaaatgaa aatactagaa aagtaagtga agagataaga aatggtagcg aagaaacaag
    47161 agttgctaat gaagtagcta gacaagaatc agaaactaca agagaagaaa acgaagacct
    47221 tagaaaaagt aatgaagaaa caagagaaga aaatgaagaa ataagaaaaa gtaatgaaaa
    47281 tactagaaaa gcaagtgaag aagtaagaaa cactagtgaa gaaacaagaa atactaatga
    47341 agaagctaga aaagcaagtg aagaaataag aaaaactagt gaaacaacca gaaataccaa
    47401 tgaggaagct agaaaagtta gtgaaacaac aagagaaaca aatgaagaaa caagaaaagc
    47461 aaatgaaata ataagacaaa attcagagac taaacgagaa gagaatgaag agcttagaaa
    47521 aagtaatgag gtaactagag aactaaatga gtcaactagg cagacatcta taattaatat
    47581 gcagaaaaaa gtagatgata aagtagatga ggttgataac aaaatagttg aagtaaatac
    47641 tgctaagaca gatatgacaa caactgttag caataaaata actgagtttg aaaaaaggtt
    47701 caatgaatta gaaaatttag atacagcagg agaaatatta caatcaaaag aaacaacaga
    47761 tggacagata aaagacactt taaaagagag attaacttat gattttaata aactagattt
    47821 aaaaatagag caacttattg ctggtggaat aaatgtagca tttaataaat catatgatac
    47881 atctgaatgg attgaagttg atggaggatt tgaactttca gtagagcata atcttgttac
    47941 tcaaaaaata ttagtctctt caatagataa acttaatagg aaaagtttga ttacatctta
    48001 taaaattatg gatgacaata atataatact gtttaatgaa gttgctatag acattgaagt
    48061 tacagtagtt aatggtggtt ctactattga acttataaaa tttactatta atgatgatat
    48121 agagtctctt gaaagtgctt attctagtat agagacaaaa agattattaa aagatggatt
    48181 agataaaaaa gctaatttag aacatactca tgatatatat gttgagaaag ttgaaggcaa
    48241 agaactctct acagaagatt atacaactga agaaaaagaa aaactttctc aattagatac
    48301 ttataaaaat aaagaaacaa aatttaatac aaatggttct ataacagaaa cattagataa
    48361 tagtatcaag tatattacaa agtttaatac aaatggctct atatcaaaag aaaagtatat
    48421 aaatgatata ttaataaata caacaataac taactttaaa aatggaatga tagaagaatc
    48481 tgttacaaat gaaggggtga tttagtgagt tgggcagagg tttataaaat aaatagtgat
    48541 attcaaggag aacctttaaa ttatttaaat tatttacaag atttgaaatt aaatggttct
    48601 gaaagttatc ttttatatga aggtaatcat aggatttggg aagagctgta cttaaatagt
    48661 ttatacttat tttctgatag aggaattaga gaagttgtgt atacagcttt ttcagaaaca
    48721 gacattgaca atctgtttga taaaagtact aagctggggg aacaattaaa tgccttttac
    48781 agaacagata tatttagttt ggggaatgct gataatgtag taaaaggaat gactgtagag
    48841 cattataatt cattagagga aaaatttaaa gcagggtatg atagatatgt tacaagagaa
    48901 caagaaaagt caactatagg agcatggttt aattctactt ttagtttaaa tagtactgat
    48961 ttagaaagtc ttacaactat agatgaaata ttagcagata cagaagctac taatgcgata
    49021 cttaataata gtaatgcaat agtagcttta actatgtgta aatcaagcat ggatgcagtt
    49081 gtcgcaagcc caaatgcaat ggatttatta ggtcaataca ttttaaaagt tacagcagag
    49141 ccagctgtta taaaagcgat tttagaaaat aatgtaatta gagaagctat aataaatagt
    49201 actgaagcaa tgactcatat agcaacaaat catgaatcag ttaggatgat atttgagaat
    49261 ttagaagcca cacagctact attagctaat caagatacat tagatttagt tttagcaaat
    49321 acaaatgtta ttagacttgt acttacaaag attttagaaa ctcataatag tatatttaag
    49381 ttagatataa atactttaat aacgaatatg actagtatgg ttaattcaac taacatagaa
    49441 taccaagata agatttttcc tatagttgaa actatgaata ctaattttat aagtataaaa
    49501 gatttattat caaataataa cttagacaaa aataatataa ttgctatatt tcaatgcata
    49561 gaaaataatt taagtgttat aacagcttta tcaagtgacg aagtagcttt caattctatc
    49621 aaggaaattg atttagctat agcaaaaacc gcagcgaagc tagcggggat agacaatata
    49681 aatatcaaca cttcggatgc gttagctaga agtgataaat acatgaatgc tgtggcaagc
    49741 tcacaaatag caatgaatgc tgtggcaagc tcacaaatag caatgaatgc tgtggcaagc
    49801 tcacaaatag caatgaatgc tgtggcaagc tcacaaatag cagtaaacac aataataaat
    49861 aattcgggat tcttaaatat agtaatctct agctcgacag ccatgtctgc catcgcaagt
    49921 agctcgacag ccatgttatc tatttctaaa agcccgcttg cgcttaataa aatacttaaa
    49981 actgaaattg gaagaactag tctagcaaat tcaagctact tacaaactaa ttatagtaat
    50041 attagcactt ctactcaaaa tactacatat tttgcaaaag gctctaatgc tgtaatagat
    50101 agtggtagta gaaattcaaa tgatacaggg ggcatggtaa gtagtacaac accaaatcaa
    50161 tgtatattta tatgtttaac aataggttca tggagtaatg gcactaatac aacaggaaca
    50221 ataagtcatt tacaaactgg ttcacaagtt gcaacaagaa caacaacaac aggacctatt
    50281 catcaaggaa caggagcaac tgcacaatat atatgtgtag gaggatgtaa gtttacagag
    50341 agttcagatt ctggagcgtg gggatgtatg gcttatgcta aatagtacaa aataactttt
    50401 attagaagaa ggtgattaat tgttaaatga agatgtagta aaaaatatta ataaattaaa
    50461 taatgagcag gataatatta acctagaact tagtaagaaa gcaaataaag aagatttaga
    50521 aaaattaatt cagggaggtc ctaatgtatc tgtatctaaa gatatatcaa taaataactg
    50581 gatattagaa gaaaatgtat acacagttat agttgagcat aaccttgtaa ctagaaaagt
    50641 gcttgtaagt ttaatagata aatctactaa taacaatgta ttttgctcat accaaatctt
    50701 agatgataat agtataaaag tttttaatga atcgaataat gaactagaat gtatagttgt
    50761 aaatggaaac tcagctatta acatgatttc agcaactatt gatgataata gaagtactga
    50821 aacaactact tattcatctg taaagataga agctttatta aaagttctag aaaataaaat
    50881 tgatgatata gaaaatctca aagaaattga caatataaaa tgtagtacta atacaggaga
    50941 atatacaata gaaaatagca aaaagggcta tttaactaat tttaatatag aaggaaagac
    51001 attaattgat ttatggggaa aaactagttc agatttttct ttatggaaag caacttttgt
    51061 agatggaaaa ataaatatac taacagaaaa tgatataaga tattctaatt tttttacaat
    51121 caattacact tcatataaac cagataccat atatacaatc atagttgatg ttgataaaaa
    51181 cactttaccg agtacaagtg gaatatatat tcatagttta ggcgaagaaa attcagtatt
    51241 tattcctaat ctgacaaata tagctatacc aggaggagta attggtaaat ttaaatatac
    51301 atttacaaca atatcagact taagtgattg taatgttgtt ttaaggagtg ttttagataa
    51361 cgatacactt acatctggtt atgaagtaag tttgaaaatt accatattag aaggagatta
    51421 tacagatatt aatatagatt actctaatga actattaagt gttgggcaaa gagataaaat
    51481 agaattttta agttatcaat atagtggaat taatatcttt aataagaatg ccgattttaa
    51541 agataattat attttacaat accttaatgg agaggaactt atttctgaag ctagtaatca
    51601 taaatatacc ctagactata tagaaataga accagataca gagtatactt tttataattg
    51661 tagtagaaat atttgttggt atgatataaa taaaagtttc ataccagcac cattaaatga
    51721 aagaataata ggagataaag atatttttta tgttgctaga agtcctaaaa atgcaaaata
    51781 tctaagagtt actataataa aagatttaca tgataatggg aataaaacaa ttataactaa
    51841 aggaaataaa tatgataaaa agacaattcc atatacatta agaagtttac caaatggagt
    51901 gaaagatgaa atagtttata aaaataataa atattactta ataaaaagat gtgaggaaca
    51961 tacttatact gatattggaa atcttaattt atcacatgta tatgataata ctctgcaatt
    52021 tatgggaaca ttaactcctc aagctgttgt agatagttta gacatagcat atgttttatg
    52081 taataattta aatgggaaaa gtagaaatga ttttaacaat aatgacatag agggatgctc
    52141 aactactggt agtggtgata tagcatttaa aatattaaaa agtaaactta ctacacaaga
    52201 tggaaatggg tttaatgaat ggataaaaaa taatccaata actatcatct accaacttgc
    52261 agaaccacaa gaaattgaat taacatcact aaatttagaa caatataata atcaaactag
    52321 atttatttgt aactttggta ttgtgatacc agacattagt tttgaaagta cacaaaattt
    52381 aggtagccat atagaagtta tcagaaataa tataaaaaat tacaatgtta gaactgattt
    52441 tccattttca ataaactttc ttaatggatg gcagccatat cttggatatg ctagtgctgt
    52501 tggaaactat tgcacaaata ataactttgt aacaattaat gcaactatta atggaggtgt
    52561 tacaacggca ggtactatca ttggaaagat accttcgaaa tatgcacctc gtaaaaacat
    52621 aatagtaata tttcaaacaa cagatggaaa gtattataac ggaatcattc gtacaaatgg
    52681 agaaattgag atatattata atgatataac ttatcgtagt tggctgtatt tatatgtaaa
    52741 ctatttaatt tagaaaggaa aaataagatg gatatagaaa agaaaataga aattttaata
    52801 gaatatggat ttgagaatga tttaaataat atagataatt actttattgc agatggtaaa
    52861 aaaatattta ctccagtgat aaaaaacgga gagttaatta aaacaggaga acaggtttat
    52921 aatgagtggt cagaattaca aaataatcca cctaaatcag agccaagtat agaagaaata
    52981 aatgcggata aaattacaat tttaatagaa aatcaaaagc aacaagatag tttattagta
    53041 gataatgctt atagaattgc tatgttagaa cttaacacaa ataacgtgtt ataaaactat
    53101 aaaaaacgga gggaacaaca tgtataatat tttaaaaaga atgattgagc aaaaaaatta
    53161 tgaaactaaa gaagaattgc agactaaatt ggatgtattc tatgcattaa atagaattaa
    53221 agaaaatgaa tacacagaat taacaaatat gataaacaaa gaagaagtat aaaaagaacc
    53281 tattatctaa aatataaagg ttcttttttt atatcaattt tagcaggagg tcatcatgga
    53341 acaattatta acagaattaa gtagtttagg agcaatagga atcttatgtg ctttactatt
    53401 caaaaatact atgcaggaga aaaaagaaga tagagatatg tataaaaaga cagtagaaaa
    53461 ctttattgaa ctatcaacac aacaacaaga aatcaataaa aatatacttg ttgaaatggg
    53521 agcaatgaaa actgatgtgg aggaaataaa ggaagatgta acagatataa aggtgatgct
    53581 acagaaagaa ggtgataaat gatgaaagta gtaatagtac caggacatac actaacagga
    53641 aaaggaacag gggcagttgg ttatatagat gaaggaaaag aaaacagagt tttaactgat
    53701 ttaattgtta aatggttgaa acaaggtgga gctattgtgt atactggaaa agtagataaa
    53761 tctaataact atttagcaga acaatgtgaa attgccaata ggcaaaatgt agacttagca
    53821 gtacaaatcc atttcaacgc aaataaaaca actctaaatc ctatgggtac agagacaata
    53881 tacaaaacta acaatggtaa ggtatatgct gaaagagtca acaaaaaact atcaacaata
    53941 tttaaaaata gaggtgcaaa atcggatgta agaggtcttt actggcttag tcatacaaaa
    54001 gctcctgcaa tattaataga agtgtgcttc gtagatagta aagcagatac agattattat
    54061 attaggcata aagacatagt tgctaaatta atagcagaag gtattttaaa taagataata
    54121 gataataaag agaatggtga gggaaaaatc atgtataaac atacaatcat ttatgatgga
    54181 gcggttgata aaatccctgc aactgttgtt ggctggggtt ataatgatgg aaaaatacta
    54241 atatgtgata taaaagatta tataccaggt cagacagaaa atttatatgt tgttggtggt
    54301 ggagcatgtg agaagatagg ttccatgact aaagaaaatt ataccatgat aaaaggtaat
    54361 gatagatttg acactcttta taaggcatta gattttataa acaagtaaat cgattaggag
    54421 gtagtaactg gaaatagtta ctacctcttt ttttattcat tttcagcttt ttcaataatt
    54481 atttttccat cttcaagtgt aactataact tttctttcat tttgagagat acctagttct
    54541 ttaacccaat taataggtaa agataatcta gtagtagtat agccatttcc acttttatga
    54601 aaacttatat ttaattctct ttgttccatt taattaccat ccttttttaa ttcttttgta
    54661 aagaaaacta atagtgagat acttattaat aatccaataa tattccatat atcaaaactt
    54721 tttattaaga gtattacatc aaacactata gttattaaaa caacagcaac acatattttg
    54781 taaaaatttc tattcatggc attttagaaa gtatgttata atattagaaa gaagtcacct
    54841 agaaggaact gcatttcctt ctaggcttaa ctcttatagt tctttaatta gtcttaaaac
    54901 tgtaagagct atatttagta ttaataatat aaaagagaga acttttttaa ttatattaaa
    54961 tttgttctct tttttatttt ttcttctttc taatctcccc actttctttg tcctcctttc
    55021 ttagtttttg ttttctcacc tccttgtcta taaatatatt ataacattac gggacgtata
    55081 atgcaatgct tttatttaca tttttcaata aatttataaa attcaaaaaa tgataattga
    55141 caacatatac tacaatatat tgattaattt tagttattat ttttgtttgt atattaaaat
    55201 ggagagggag aaaatcttta ataagatata tcttattact aaaaagcata tcatgaaaaa
    55261 gatattgata aatttaataa atagagtaga aggtagaaac tataaacaat cactaccttc
    55321 tttttttatt cattttcagc tttttcaata attatttttc catcttcaaa agtaacaaga
    55381 acatcccttt catcaggaga gatattcatc tctttaatcc atgacattgg aagtatcaat
    55441 ctgggtgtaa aagagccttt gccactttta ttgaatgcaa ctctaagttt tctttgttcc
    55501 aataatatca ttcctttcta ctattaataa atgccagcaa taataaagta aataccaaag
    55561 caataagagc tttaaaagta aaacttgtta ttatattaat aatatttaaa actatagtga
    55621 taccaagaat aatcatacaa attctataaa atttattatt catattaaat tagaaaatgt
    55681 gttataatat tagaaagaag ctacctagaa ggaaggtatt ttcctcctag gattgaaact
    55741 tataattctt taatcaatct tagtattgcg agtactagat taattaaaac taatgtgaaa
    55801 gagaaagcat ttttaatttt attaaatttg ttttctcttt tattttttct tctttctaat
    55861 ttccccactt tctttgtcct cccttctaag ttttttattt tcttacctcc tttctatatt
    55921 tatattatat catcacgtga cgtgaaagtc aataaatatt ccatattttt caataaaatt
    55981 atactgataa actatatttt ttacaaataa aaataaatgg tgacaaaacc aaacttgcca
    56041 ccattttgcc accgaaaata aataatagaa taaatttaaa ttaaacataa taaaacataa
    56101 acaacaaaac ttaccttaat aaaacattga aataccaaca cttgtaaaaa ataacaacaa
    56161 taaacaaata aaatagaata atattacaac ttaagtaaat aataattttg aataataatt
    56221 tacggaggta ttcatatgtt taaacacgat aaagcattat taaaagaagt aaaagtagaa
    56281 agaccaaatc ctcaatatgc tgttttaatg caagaacagt tgggtggtgc aaatggagag
    56341 ttaaaagcag ctatgcaata cttgtcccaa agttttagaa taaaagaccc tcaaataaaa
    56401 gatttatttc ttgatatagc agcagaagag cttagccata tggaaatggt agcacaaact
    56461 ataaatttat taaatggaca tgatgttgat tataatgcag ttaatacagg cgaaatagaa
    56521 acacatgtat taactggtct atcaccagtc ttaataaact catcaggagc tccttggact
    56581 gctaattacg ttacagttac aggggattta gtagctgact tactttcaaa tatagcttct
    56641 gaacaaagag ctaaggtagt ttatgagtac ttgtatagac aaatagatga taaatatgta
    56701 aaagaaacaa tagatttctt acttaataga gaagaagcac ataatgctct atttagagat
    56761 gctttaaata aagttaaaga tacaggttca aatagagatt ttggagttac agaagattct
    56821 aaattatatt tcgatttgtc tactccaggg ccaaatcacg atactaagat agatattaat
    56881 cctccttctt ttgaaaaacc tttaaaaaaa taatttgata ttttttattt tgttttagta
    56941 gttataaaaa ttatttacta gaagaattaa ttatatgaaa aattaaatat gtatagttaa
    57001 aaatgggtat acacttatta taagtgtata tctatttgtt tattgcaaaa catataataa
    57061 aataacaaat gaggtggtat tttggacagt aatagaaaac ctaataatct aataaatgaa
    57121 aaatctccat atcttttaca gcatgcttat aatcccataa actggtatag ttggaatgat
    57181 gaggctttta aaaaagcaaa agaagaggat aaaccaatat ttttaagtgt aggatattca
    57241 acatgtcatt ggtgccatgt tatggaaaaa gaatcttttg aagatgaaga agttgctgaa
    57301 ataatgaata gaaactttgt ggcaataaaa gtagataaag aggaaagacc tgatgtagat
    57361 agtgtgtata tgacagtttg ccaagctatg acaggtagtg gtggatggcc aatgaccata
    57421 ataatgacac cagataaaaa accttttttt gcgggaacat atttcccaaa atattcaagg
    57481 tataatagac ctggagttat agatttatta gagaatgtat ctgaaaagtg gaatacaagc
    57541 agagatatat taataaaatc tggagatgaa ataatagaag ctcttaagga tgattttggt
    57601 gtaaaaaata ctgagggtga tttatcaaaa gagatgttga gttcatcagt tagagtattt
    57661 aaggctattt atgatgaaaa gtatggtggt tttggtaatg ctcctaaatt tccaagtcct
    57721 cagaatctta tgtttttaat gaaatattat agtatagaaa aagacaaaga tgtgttaaaa
    57781 atggtggaaa aaactttaga tggaatgtat agaggaggct tgtttgatca tattggattt
    57841 gggttttcaa gatactctac tgataaaaag tggttggctc ctcattttga aaaaatgcta
    57901 tatgataatg ctatgcttac tatagctttt ttagatgcgt ataaaataac aaagaaagag
    57961 ttgtataaag aaattgctat aaaaactata gattatgtag ttagagagat gaaggataaa
    58021 gaaggtgggt tttattcagc acaggatgct gatagtgaag gtgaagaagg taaattttat
    58081 acatttaatc ctcttgagat aattgaagtt ttgggtgaag aagatggaac tttctttaat
    58141 aattattttg atataactag tagtggaaat tttgaaggca aaagtattcc taatcttata
    58201 aaaaataaag aatatgagag acataatgaa aagatagctg accttagtaa aaaggtattt
    58261 gaatatagaa aagaaagaac atctttgcat aaagatgaca agatacttac atcatggaat
    58321 gcattgatga tagttgcttt aacaaaggca tatagtactt taaaaaatga catatattta
    58381 gagtattcaa ataagtgtct taactttata aataataatc ttgtaaatga gtcaggtaga
    58441 ttattagcta gatatagaga tggaagttcc gactatttag catatttaga tgattatgct
    58501 tttttaatct gggcgtatat agagctttat gagtcaacat ttaatatgaa atatttagaa
    58561 aaggctttaa atttgaatga aagctgtatc aacctttttt gggattatga aaaaagtgga
    58621 ttttatatat atggtaaaga tagtgaaaat ttaatagcaa gaccaaaaga tttgtatgat
    58681 ggagctattc catcaggaaa ttctgttcaa ttatacaatc ttataagact tgcgaaaatt
    58741 actggagata atagacttga agaaatgtca tataaacaat taaaactgta tgtggataat
    58801 gtaaagagtt ctccaactgg ctacagcttt tatatgcttt cattgatgtt tgaactttat
    58861 tctactaagg aaattatatg tatttttaag gaagattctg atttaattgc atttaaagaa
    58921 ttgataagtg aaaattttat accaaatgca acttttttag caaagaaata caatgaagaa
    58981 aacactatta taggtttttt aaataactat atattgaagg atgataagac tagttattac
    59041 gtgtgtcaaa gtaatagttg tagtcaacca attaatgatt tacaaaaatt aaaagatatg
    59101 attttaggag tagaataatc ataatagcga aaaaggagat gctttaaaat aaaagtctaa
    59161 tcatctcctt tttttgtata aaaaacagaa aaagagttcc taagaacacc taatctatgt
    59221 aatgattgtt ttgttaaaaa ataaaaatga cattatagtt atataaaata ttgtactata
    59281 aaaaagtggt attatagatg cgatagtatt aatctttttt atttactcta tttcttcttt
    59341 ttgcaaattc ttcaagtgct tcagatttaa ttttatctat ttcttcatat tccataaaat
    59401 tagcatcttc ttcaaagcca tcttgttctt caccattaaa acgatacatt ttttttagta
    59461 aactccataa ggtctctaat tcatctttgg taaattcgtg aaatacatct gccataaagt
    59521 ttattccagt cctactacat gtcaccataa ccttttttcc taagtctgta actttaacat
    59581 taattgctct cttatcatga ggacttggaa ttacatcaac atatccattt ttttcaagat
    59641 tagcaactag tctatttata ttttgtttac ttgtacccat ttttcttgca atattattta
    59701 atgttgtttc ttcctctggt aaatgaagaa ttgataaaat agtcatatac tgtcttgaag
    59761 taagtatacc aaaatattta tctccttcta tttgtatttt gtttgtaagg gtaaaaagag
    59821 ttgcatatgt ttgattcatt aaaaagagct cttttagttc atttgaataa tccatgaaat
    59881 atatctcctt tatttttaga tgttgttttg tcgaaaacag aatatcatga attaattcta
    59941 atgtcaatat ggtgtcaaaa tatattaaag tattactttt ttatgtaact attaattaat
    60001 taaattattg tataatttta tgtaaaaact tctatgtacc aatgataact tctatgagga
    60061 attaataatt cttaaatttt ttagaaagat tttgacttga aaatacttgt aatataatat
    60121 ataaattaat atactgaata aaatcaatct ggagggataa ttatgaagtg tacaaacttt
    60181 actttcaaag gagaggaagg tttagatata tatacatata aatgggaaga tgaaaatata
    60241 aaaaaaccaa aggcagttat ccaaattgca catggaatgg ctgaaactgc acaaaggtat
    60301 gagacttttg ccaaggtact tactaaaaat ggttatatag tatatatcaa tgaccataga
    60361 ggtcatggaa aaactgcaaa gataatagaa aatgttggac atttagctga aaaagaagga
    60421 tttagatgtc ttgtagagga catgtatact ttaacaaata ttataaagaa agaaaatgaa
    60481 gatttgccaa tttatctatt tggacacagc atgggttcat ttgcaagtca aagatatata
    60541 atggattaca gtaataattt atctggtctt atactatgtg gttcaaatgg aaagcaagga
    60601 atcattctaa atcttgctca tctgataatc aatcgtgaga ttaaaaagta tggaagatgt
    60661 tctaaaagta ataaaataaa taatttgata tttggcggcg aaataataag aagaaatgaa
    60721 aagactaagt ttgactggtt aagtagagat aaagaacaag ttgaaaaata tataaatgac
    60781 ccattttgtg gagtagtgtg tagttgtggc tttttttatg atttagttca agggttaaaa
    60841 gaaattgagg ataaagaaaa cttaaaaaaa gtgccacttg atatacctat ttacataata
    60901 tctggagata aagaccccat aggaaaaaat ggtaaaggag tcttaagact aagggataga
    60961 tatataaaat taggagtaaa agatgtaact tgcaaacttt acaaagatgg aaggcatgaa
    61021 ttgttgaatg aaataaatag agaagaagtt tttgaggata taatttgttg gttaaataat
    61081 aaaatagaaa tattgtaa
//
LOCUS       DAEPXW010000009        58824 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.009, whole genome shotgun sequence.
ACCESSION   DAEPXW010000009 DAEPXW010000000
VERSION     DAEPXW010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58824
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.009"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            186..1262
                     /locus_tag="KRM55_000575"
     CDS             186..1262
                     /locus_tag="KRM55_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012343477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1592846.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVD"
     gene            complement(1365..2207)
                     /locus_tag="KRM55_000576"
     CDS             complement(1365..2207)
                     /locus_tag="KRM55_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH1592847.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2391..2963
                     /locus_tag="KRM55_000577"
     CDS             2391..2963
                     /locus_tag="KRM55_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1592848.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3126..3398)
                     /locus_tag="KRM55_000578"
     CDS             complement(3126..3398)
                     /locus_tag="KRM55_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592849.1"
                     /translation="MLRERFVVRNHHNPHISGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3512..4384)
                     /locus_tag="KRM55_000579"
     CDS             complement(3512..4384)
                     /locus_tag="KRM55_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1592850.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4680..7787)
                     /locus_tag="KRM55_000580"
     CDS             complement(4680..7787)
                     /locus_tag="KRM55_000580"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBH1592851.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7880..8112)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8287..8814)
                     /locus_tag="KRM55_000581"
     CDS             complement(8287..8814)
                     /locus_tag="KRM55_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBH1592852.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8849..9634)
                     /locus_tag="KRM55_000582"
     CDS             complement(8849..9634)
                     /locus_tag="KRM55_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBH1592853.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9644..9901)
                     /locus_tag="KRM55_000583"
     CDS             complement(9644..9901)
                     /locus_tag="KRM55_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBH1592854.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9920..10378)
                     /locus_tag="KRM55_000584"
     CDS             complement(9920..10378)
                     /locus_tag="KRM55_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBH1592855.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10418..11122)
                     /locus_tag="KRM55_000585"
     CDS             complement(10418..11122)
                     /locus_tag="KRM55_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBH1592856.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQTNREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11132..11767)
                     /locus_tag="KRM55_000586"
     CDS             complement(11132..11767)
                     /locus_tag="KRM55_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592857.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12148..13188
                     /locus_tag="KRM55_000587"
     CDS             12148..13188
                     /locus_tag="KRM55_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1592858.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13651..15006)
                     /locus_tag="KRM55_000588"
     CDS             complement(13651..15006)
                     /locus_tag="KRM55_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBH1592859.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15032..15301)
                     /locus_tag="KRM55_000589"
     CDS             complement(15032..15301)
                     /locus_tag="KRM55_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH1592860.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(15591..17531)
                     /locus_tag="KRM55_000590"
     CDS             complement(15591..17531)
                     /locus_tag="KRM55_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592861.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYNIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENDNSDEKQPNTPKDD
                     VESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVFGTNEH
                     SFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCILTPIMI
                     GSILIVNPDTRKSIIKFIKLKK"
     gene            complement(17714..19189)
                     /gene="spoIVA"
                     /locus_tag="KRM55_000591"
     CDS             complement(17714..19189)
                     /gene="spoIVA"
                     /locus_tag="KRM55_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBH1592862.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(19361..20656)
                     /locus_tag="KRM55_000592"
     CDS             complement(19361..20656)
                     /locus_tag="KRM55_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1592863.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSVINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPIASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMVYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENATKVS"
     gene            complement(20840..22249)
                     /locus_tag="KRM55_000593"
     CDS             complement(20840..22249)
                     /locus_tag="KRM55_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1592864.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(22301..23440)
                     /locus_tag="KRM55_000594"
     CDS             complement(22301..23440)
                     /locus_tag="KRM55_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1592865.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            23759..24409
                     /locus_tag="KRM55_000595"
     CDS             23759..24409
                     /locus_tag="KRM55_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1592866.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(24566..25585)
                     /locus_tag="KRM55_000596"
     CDS             complement(24566..25585)
                     /locus_tag="KRM55_000596"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH1592867.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(25616..26230)
                     /gene="plsY"
                     /locus_tag="KRM55_000597"
     CDS             complement(25616..26230)
                     /gene="plsY"
                     /locus_tag="KRM55_000597"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBH1592868.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(26265..27584)
                     /gene="der"
                     /locus_tag="KRM55_000598"
     CDS             complement(26265..27584)
                     /gene="der"
                     /locus_tag="KRM55_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBH1592869.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(27618..28946)
                     /locus_tag="KRM55_000599"
     CDS             complement(27618..28946)
                     /locus_tag="KRM55_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBH1592870.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPENILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(29184..29384)
                     /locus_tag="KRM55_000600"
     CDS             complement(29184..29384)
                     /locus_tag="KRM55_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592871.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(29386..30318)
                     /locus_tag="KRM55_000601"
     CDS             complement(29386..30318)
                     /locus_tag="KRM55_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH1592872.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKENESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(30363..31295)
                     /locus_tag="KRM55_000602"
     CDS             complement(30363..31295)
                     /locus_tag="KRM55_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH1592873.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(31350..32639)
                     /locus_tag="KRM55_000603"
     CDS             complement(31350..32639)
                     /locus_tag="KRM55_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1592874.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(32668..33360)
                     /locus_tag="KRM55_000604"
     CDS             complement(32668..33360)
                     /locus_tag="KRM55_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1592875.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(33375..34136)
                     /gene="pgeF"
                     /locus_tag="KRM55_000605"
     CDS             complement(33375..34136)
                     /gene="pgeF"
                     /locus_tag="KRM55_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBH1592876.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(34133..34594)
                     /gene="nrdR"
                     /locus_tag="KRM55_000606"
     CDS             complement(34133..34594)
                     /gene="nrdR"
                     /locus_tag="KRM55_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBH1592877.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(34616..34879)
                     /locus_tag="KRM55_000607"
     CDS             complement(34616..34879)
                     /locus_tag="KRM55_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH1592878.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(34983..35756)
                     /gene="sigG"
                     /locus_tag="KRM55_000608"
     CDS             complement(34983..35756)
                     /gene="sigG"
                     /locus_tag="KRM55_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBH1592879.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(35848..36570)
                     /gene="sigE"
                     /locus_tag="KRM55_000609"
     CDS             complement(35848..36570)
                     /gene="sigE"
                     /locus_tag="KRM55_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBH1592880.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(36595..37467)
                     /locus_tag="KRM55_000610"
     CDS             complement(36595..37467)
                     /locus_tag="KRM55_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBH1592881.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(37757..39031)
                     /locus_tag="KRM55_000611"
     CDS             complement(37757..39031)
                     /locus_tag="KRM55_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH1592882.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(39315..40472)
                     /gene="ftsZ"
                     /locus_tag="KRM55_000612"
     CDS             complement(39315..40472)
                     /gene="ftsZ"
                     /locus_tag="KRM55_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBH1592883.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(40662..41015)
                     /locus_tag="KRM55_000613"
     CDS             complement(40662..41015)
                     /locus_tag="KRM55_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBH1592884.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(41114..41788)
                     /locus_tag="KRM55_000614"
     CDS             complement(41114..41788)
                     /locus_tag="KRM55_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH1592885.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(41793..42491)
                     /locus_tag="KRM55_000615"
     CDS             complement(41793..42491)
                     /locus_tag="KRM55_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH1592886.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(42514..43254)
                     /locus_tag="KRM55_000616"
     CDS             complement(42514..43254)
                     /locus_tag="KRM55_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HBH1592887.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(43524..44750)
                     /gene="murG"
                     /locus_tag="KRM55_000617"
     CDS             complement(43524..44750)
                     /gene="murG"
                     /locus_tag="KRM55_000617"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH1592888.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(44768..45898)
                     /gene="spoVE"
                     /locus_tag="KRM55_000618"
     CDS             complement(44768..45898)
                     /gene="spoVE"
                     /locus_tag="KRM55_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBH1592889.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(45950..47305)
                     /locus_tag="KRM55_000619"
     CDS             complement(45950..47305)
                     /locus_tag="KRM55_000619"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBH1592890.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIKAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(47324..48292)
                     /locus_tag="KRM55_000620"
     CDS             complement(47324..48292)
                     /locus_tag="KRM55_000620"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBH1592891.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(48333..49706)
                     /locus_tag="KRM55_000621"
     CDS             complement(48333..49706)
                     /locus_tag="KRM55_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBH1592892.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(49873..51852)
                     /locus_tag="KRM55_000622"
     CDS             complement(49873..51852)
                     /locus_tag="KRM55_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBH1592893.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(51864..52211)
                     /locus_tag="KRM55_000623"
     CDS             complement(51864..52211)
                     /locus_tag="KRM55_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592894.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(52692..53627)
                     /gene="rsmH"
                     /locus_tag="KRM55_000624"
     CDS             complement(52692..53627)
                     /gene="rsmH"
                     /locus_tag="KRM55_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBH1592895.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEINPRSRSAKLRVAEKI"
     gene            complement(53657..54403)
                     /locus_tag="KRM55_000625"
     CDS             complement(53657..54403)
                     /locus_tag="KRM55_000625"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBH1592896.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(54797..56083)
                     /locus_tag="KRM55_000626"
     CDS             complement(54797..56083)
                     /locus_tag="KRM55_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH1592897.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KNSNNYKVDKLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDIIKDITFEEVEERLKDHFKEEYCVISIVEPK"
     gene            complement(56098..57363)
                     /locus_tag="KRM55_000627"
     CDS             complement(56098..57363)
                     /locus_tag="KRM55_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH1592898.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKVGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            57679..58776
                     /gene="ychF"
                     /locus_tag="KRM55_000628"
     CDS             57679..58776
                     /gene="ychF"
                     /locus_tag="KRM55_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBH1592899.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        18441 a        10657 c         6335 g        23391 t
ORIGIN      
        1 cttttataga attttcacaa taaaaagtca ttttacttcc gtatttaatg caaaagtaga
       61 aattaaactt aatataaaaa atatataaca aatttttttt atatttctag aagaaaagta
      121 tactcttttt tgtttaataa tgctaaaatt gatttgtatt gaattttgat taggaggaaa
      181 ttattatgaa agctcaaaga ttaaatgctg tacttgaaca aatgaaaaaa gatgatattt
      241 ctcaaatgtt agtaagtgac cctacttcta tattttatct tacaggagta ctaatccatc
      301 caggcgaaag actattagca ttatacttaa atttaaatgg caataataaa ttatttataa
      361 atgaattatt cccagtttca gaagatttag gtgttgaaat ggtttggttt aatgatactc
      421 aaaatccagt agaaataata actgaacata tagacaaaaa tgctactatg ggtgttgata
      481 aaaactggcc agctagattc ttattaaact taatagaatt aggtggagga agtaagtttg
      541 taaattcatc ttatataata gatactttaa gaatgtgtaa agatgaagaa gaaaaagagt
      601 taatgagaat agcttcaaaa ttaaatgaca aggctatgga acaacttaaa gctactgttt
      661 ctggtgaact tacagaaaaa caacttgttg gtaaattatc taaaatatat gaagacctag
      721 gtactgatgg attttcattt gaccctatta taggttttgg acctaatgga gctaatccac
      781 atggtgaacc tggaaatgca cttgtgaaac caggagatgc aataatctta gatataggtt
      841 gtataaaaga taactattgt gctgatatga caagaactgt attctataaa gaaatacctg
      901 aaaaaggtag agaaatattt gaaatagttc ttgaagctaa taagagagct gaagctattg
      961 taaaaccagg tgttagattc tgtgatatag atgctgctgc tcgtgactac ataactgaaa
     1021 agggatatgg acagtacttc actcatagaa ctggtcactc tataggactt gaagttcatg
     1081 ataaaggaga tgtatcttct ataaatacag atactgtaca accaggaatg atattctcta
     1141 tagagccagg tatatattta ccaggtgagt tcggagttag aatagaagat ttagtacttg
     1201 ttactgaaga tggttgtgag atattaaaca aacatgacaa agaaatatgt gtagttgatt
     1261 aattctaaaa tcaatttgat aaaattaaaa agccatataa aaatgtttta aacattttta
     1321 tatggcttta atttctcaat ctatgattta tttcaatcca ttatttatat tgcagttatt
     1381 aagattgcac cctttgaagt atatgtcccc atcactgaac caatttcaca gattacaaca
     1441 tctttgtatt ttacatcctt ttccataact tcccttacct tttgagcctt ttctgggcaa
     1501 ttagcatgtc ctataaataa aaccttttct tctttatctt taatttttga ctctactaaa
     1561 gtaatcagct ttttcaaact gtttccttca cctcttgcct tatctatagg agttacaacg
     1621 ccatctgcaa cttgtattat cgccttaaaa tttaaggtat ttataatttt tcctgctatt
     1681 ggatttattc taccaccctt aatagcattt tctaaagttt caagtgttcc aaaaaatgga
     1741 ggattatctt tatatttatt tattattgaa acaatctctt caatttcttt tccttctttt
     1801 attaatattg ctgcttttaa cactaattgt cctattccaa ttgacccact aagtgaatct
     1861 ataacctcaa ctttcttgtt atttccttcc ttttcaaaca tatcttttgc taaaagtgca
     1921 ctattataag tcccagataa tcctgaactt atattaatca ctaatacact ttcttcctga
     1981 caatggtatg cttctaaaaa tttatcagga gaaggacatg atgtttttgg tagtacttta
     2041 ctctcactca tttttctata gaaagtttca ttatctattt cctttccaga tatataactt
     2101 tcttctccaa aagatacatt taaaccaaca acttctatgt tgtatttttc tattatatca
     2161 tcaggtaagt cacatgcact gtccactatc aattttattt tatccatatt aacctcacta
     2221 taagatatta ttttatttat tcagtcggtc gtacgaccga tttaattatt attttatata
     2281 ttgaatgaaa aaaagtcaat agatatagat tctcgcttta ttgacaataa atatccataa
     2341 gcttataatg ttattaattt gttataaata tacatggaaa ggtaggtttt atgaaaacaa
     2401 ataatatgaa acaggctatt ttatcatctg caaccaattt aatagccaaa aatggagttc
     2461 aaaatactag ccttgctgat attgcaaaag atgtaaatat aagtaaaggt actttgtatt
     2521 atcactacgc atctaaagat gatattatat atgatattgc ggatactcat ttagaagtta
     2581 taactagtgc tatactaaac tgtgtaaaaa atgtcaaatc aaaaaattct caaatagaaa
     2641 tggttaactt aatcttagag aaaatatcta ctatagaaag tcgtggtagg gtacatatgt
     2701 atcttatttg tgaggcaatt acttcaaata atgatttaaa ggaaagaata agattaaaat
     2761 atattgaatg gagaactact cttaaatctg aaattgttga atcactagaa aaatataata
     2821 gtagcgaaaa tgaacaggat gctgaatcat tttctttttt actcatgtca atagttgatg
     2881 gtttagttgt ccaaagttta ttaaaaacag aaaaaatacc ttatgaaaat atagcttctt
     2941 ttttagttaa tcattggatt taaacttaat acttagataa ttaataaaag tgaactattt
     3001 aagttatcta ctttaacagt tcactttctt atttattctc aataattttt acttaaaaca
     3061 ttcaattttt atttaaacct tcatggaatc acaaaataaa aatctcttat aaatttaaaa
     3121 tgtttttatt tatgttcatg tgtatgccca tctgaatgtt catgaccatg tgtatgtgta
     3181 tgctcatggc tatgctcatg agtacctgaa aaaccatcat catgattatg gtcgtgacct
     3241 acaccattta catgctcatg ttcatgccca tgactgtgag aatgttgatg tgaatgttca
     3301 tggttatctc ctccacagca tccttctcct ccagtcccac aacacccact tatatgtgga
     3361 ttatgatgat ttcttactac aaatctctct cttaacataa ttcttatacc tcctagtata
     3421 ttattgagta cttcatgtac cccattaact acagtataca tctaactagg tataatctca
     3481 atacatatgg cattttttaa catatataat cttaaagaaa tttatcctta aaacctccac
     3541 cttttacttc ttcaacgtta ttgacagaaa taaaagcttc actatccata tcataaatta
     3601 aatctttaaa tttacctatt tcatttgcag atattatgca ataaatcatc tttttcttat
     3661 tttgtgtata tgcaccttct gcctccaaaa aagtgactcc tctacccatt ttattcatta
     3721 tcactttgga tatttcatca tatttatttg atattaaaag tatagatttt tttctatcaa
     3781 agcaatcttt tcctatatcc atagtaaaag aaattatata cattgtaatt aaagtgtaca
     3841 tcaccaattt agctccaaat aaaaaagctc ctgcacatac tacaaaaaaa ttaataaata
     3901 aaaatgtatt tttcataggt atatcatact ttcttttcat tatggctgct attatatcaa
     3961 gtcctccagc agtagctctt gctttaaaag ttaaccccat acctatacca gttaatgcac
     4021 caccataaat acactgtagc atagtatcat ctattgggaa atatttagca atatcttgtg
     4081 ttagccccag tgctagagaa aatagtaaca tattgacaaa acttattagc aaaaatttat
     4141 tatcaaaata ctttctagct ataataaata ttggtatgtt catcaagaaa cttgatattc
     4201 cctgatttat accaaataat ttgtataata taacacaaat tccagctact cctccactta
     4261 ataacttggc tggtgctaga tataaattta ttcctaaggt tgatagaatc atacccaata
     4321 taataagaca atattgtaaa aatatattat tatcaatact tagcttttta ctttcaccat
     4381 acatcaaaac gcaccccttt gcataataaa taaaccaccc tgcataacac acgataaatt
     4441 tacaaataaa tttatcagaa gtagtttcct aaaaatatta ttcatcctca cttaaacgtt
     4501 tattcattaa tattctatca catgacataa ataatttata tgatttatat agatttattt
     4561 attgtaaatt ttggaatatt aaaacatttt attgaataga taattatatt acataaaaaa
     4621 tccctataga aatctataaa ctaatttcta tagggatttt ggttaactaa ctattatttt
     4681 tattttttta taacttttat acctgtcata tggtcattta agttttgttc ctctaaagat
     4741 ttatcatcta ctctgtttat ttctaaagct aaagtttcag acttgatata ttcattaaaa
     4801 tggtcaacag ccttagcaat ttcatcatca ccacagtatt ctattactat attatctaat
     4861 acttcaaagt tattagattt tcttaattgc tgtactttag atataaattc tctagcataa
     4921 ccttcattaa ttaactcttc agttagctta gtatctagta taacaaaaag attgttttca
     4981 acagatacat taaatccttc cttagcagtt atacctatta atactaaatc cttattaaat
     5041 tcaaaagctt caccatctaa atcaactgtt aaagtctcac ctttttcaag tttattagca
     5101 gtttcatgag catttaattt acttaatgct ccaacgaata aattcatctt agaacctaat
     5161 aatggccctg cttccttaaa gtttggtttt aaactaaagt tcatatactc atctaaatcc
     5221 ttagcaaata ttacctcttt aacattaagc tcttctttta ttaaatcaac tacatcactt
     5281 attgtatctt caaacttacc atctactaac actttttgta atggttgacg aacttttatt
     5341 ctttctactt ctcttgaagc tctacctaaa gtaactaagt ttttagctaa atccattttt
     5401 tcttctaatt tagtatctac taactcttca ttacatttag gatattcagc taaatgaaca
     5461 gatacttctc ctgttaagtt tctatacatt tcttctgaca tatatggtgc aaatggagct
     5521 atagctctac aaagaccatg taacaattca taagttgtat tgtacactgc ttttttatct
     5581 tctgttaatt cagttgccca gaatcttctt cttgaacgtc ttatatacca gttagataaa
     5641 tcatcattta taaaatcttg tatcattctt aaagttttat ttaactcaaa tatagctaaa
     5701 ttttcttcta catctttcat taaattattg aacttagata atatccatct atcaagttct
     5761 ggtctatctt tatattctac aaaaaattca gttggattta tatcatctgt gtttgcatat
     5821 aaagtaaaga agttatatac attcttcata gtacctataa atttactttg gatttctttt
     5881 aatccatcca tatcaaattt agttggagtc catggtggag aaacatatag taaataccat
     5941 cttaatgcat ctgctccata ttggtcaaat aattccattg gatttactgt atttcctctt
     6001 gatttactca ttttcttacc atctttatca agtacaagat ctggaactaa aacactctta
     6061 tatggtgctt ttcctaatac aaatgttgat actgcaagta atgagtagaa ccaacctcta
     6121 gtctggtcta taccttctga tatatagtca gctgggaaca attggtcaaa gttttcctta
     6181 ttttcaaatg gatagtggtg ttgagcaaat ggcatagccc cactatcaaa ccaacagtct
     6241 ataacctctg ttactcttgt cattggtttt ccacattttt cacattttaa gtgtatatca
     6301 tctacatatg gtctatgaag ttcaactgtt tctggattta catcttctat agctttttca
     6361 gctaattcag ctcttgaacc aactgaatct gtatgaccac attcacatct ccatatagga
     6421 agtggagttc cccaatatct agttcttgat attgcccagt catttagatt ttctaaccag
     6481 tttccaaatc tcttctctcc tacaaaactt gggaaccatt ttacaccatt attattttct
     6541 attaatttat ctttaagttt agtcatctct atataccagc ttggttttgc atagtatact
     6601 aatggagttt gacatctcca gcagtgtgga taattatgaa ctactttttc tttgctatat
     6661 aatttatttt cagaagctag ccattttatt atttcaacat ctagcccatc ttccattaca
     6721 aatctacctt cccaaggagt agatgtaaat ttaccagttt catctactgg ttgaataact
     6781 ggtaaatcat atcttttacc tgtgttgtag tcatcttcac caaatgctgg tgctgtatga
     6841 actataccag ttccatcttc agtagttaca taatctccta ctgtaataaa aaatgctttt
     6901 ttgtcaactt ctacaaaagg cattaattgt tcatattcta aaccttctag gtctttacct
     6961 ttcatttctt ctaaaacttc ataatcttca cctagtactt tatcagctaa aggtttagat
     7021 acataatata cctcatcacc ttttttaact tttaaataat ctacatcagc atttactgtt
     7081 aatgaaacgt ttgatggtaa agtccatgga gttgttgtcc atgctaagaa gtattcatca
     7141 gcatcttttt tcttaaattt agctataact gtattagttt ttacttcttt atatccttgt
     7201 gcaacctcat gactagcaag accagttcca catcttgggc aataaggaag tattttatgt
     7261 ccttcatata tatatccttc tttgttgaat ttgtttagta tccaccatac agactctata
     7321 tagttattat ctaaagttat atatggatta tctaaatcaa cttcataagc cattctctca
     7381 gtcattattc tccattgttt ttcaaatgag aaaactgact ctctacattt ttggttaaat
     7441 tcagctattc catattcttc tatttgttgc ttgctagtaa gacctaactc tttctctact
     7501 tgtatttcaa ctggtaatcc atgtgtatcc caaccagctt ttctctttac ttgataacca
     7561 gacattgttt tatatctaca aactgaatct ttaagcgttc tagataaaac atggtgtact
     7621 ccaggatttc cattagctgt tggaggtcct tcatagaata cgaaacttgg gtcatctttc
     7681 cctttttcta aagttttttc aagtatattt atgtctttcc aataatcaaa aacttgtgct
     7741 tctgcttgtt ttacagaact gtctaccaat ggcttaaatt tcgccatgta aatcaccctt
     7801 tcctactaaa tattataatt ccaaaatttt ttattctttc acataaattt aaatactaaa
     7861 aaactcgccc cctttaaacc aaagggacga gttataaatc gcgttaccac cctaattcta
     7921 tatgtaaact aaatactagc tacatataac actctaatag tataacggta ctaaccggca
     7981 cagcttagta gaatttaatc gttcagcctg cagctcaaga gtgattttta tctttataaa
     8041 ttcattggtt ctcagcatac ccaattctct gtaaaattat ctaaagataa atgtctctat
     8101 caacgctttt aaaaatttat ctgtgtttat atgaaattct ataacaaata atttgaatag
     8161 tcaatatatt tttgaaaaat ataataattt ctatttttct tacattttta tcctattttt
     8221 aatctttgtt atagatttct caaactcaca caattattct acataaaaaa taaacaaatt
     8281 acaagcttat tctaaagttg tagcagcttc atcattacta taattataca ctgttgttcc
     8341 ttcaaatgca tttacacatt tttcatctac atcataaaaa atctcatcaa cacttcttat
     8401 ttcatcttct aacagtgatt taaatttatt tctaaatatc ttaaattctt tgactaaagc
     8461 atcatactct tttcttatct ctataacacg gttattagct tgttctataa tttgtctagc
     8521 ttttaaatca gcttcttcaa caattatctt agccttttta ttagccgcgc tacaagtgtc
     8581 ttctgctgca ctttgagcag ttattaaagt agcttttagt gtttcttcaa tattttcata
     8641 cttgtttact tggtcttgat ataaccctaa tttttcttta agagctgtat tttccctaca
     8701 tagagattca taatcttcct tgatgatatc taaaaattca tcaacctctt catctctata
     8761 ccctcttaaa ccttttttaa actctttatt ttctatctca attggagtta gcattacatt
     8821 tcctcccagc tataatttaa attagtcctt atacaattaa tcttgcttga acttttattt
     8881 ttcctttttt agtaatatct cctatttgtg ttaccttagc tcttcctttg cctctaatag
     8941 aaatcaaatc atcatttttt actattttag aagttgaagt tatcttttca taattgacat
     9001 ggactttttc tccatttatg tattttgcac tatcttgtct agatatattg taaataccac
     9061 ttatcacaca atctaaccta tctgaagata ctgtaaatga tacttcttta tattttgaag
     9121 aactattaac aatattttct ctggaaattt cctttacaat tacattattt cttgaaacct
     9181 tttctaagtt tacaattata aaatcgcaaa tatcactact tacaactact tgacaaaagc
     9241 tatcatgtat aattatatct ccaatttttt ctctttttat acctagaccc agtattgacc
     9301 ctaagtaatc tttatgagat atatttttaa atttgaaatt cccttctatt tgtaaaaatc
     9361 taagagtatc ttctatatct tcatattcca tgtaaaatgg ataaataaat acagtgcttc
     9421 tttcagcttg ttcataacct ccatccacac tgtattttat ttcatttgta gaatttaata
     9481 ttgctacagc atttttcact tcatatggat taagaaactc cgtagactta acatcatagt
     9541 tttttataca actattagcc ttgtctatca ctttaaacat tttatttttc aagtctatat
     9601 cctttatgtg atttgttagt tttaatttat ccatcctatc accttagaat ataaccaata
     9661 ctaattgtct taggaacatc aataatacta ttgcaattaa aggagaaaaa tctataggtc
     9721 catttgtata tttatacatt atagacctta ttggcccttc tattggctct gtaagatttt
     9781 ccaaaatatc aaaaatttta ctttgtcttc catttggaaa ccaagtcatc aagcttttta
     9841 taactatcat ccatgctatt atatctaaaa gataataaag tgcaattctt attgttccca
     9901 tatattaacc gcctttttac tatttatttt gccaagggaa gaatgcttta ctttctaatt
     9961 cttttttcat atttgcatct atatccacat tattaggagc tagtataaat attgatttag
    10021 aaaccttttg tatacttcca tctaagacat aaactgcccc attcataaag ttaaatatag
    10081 atttacgaac ttcagaatta gtcaatcctt ccaaattcac tataactgcc cttctttgtt
    10141 ttagatggtc tgctatagtt gcagcttcat cataaacctt aggttcaact attacaactt
    10201 tcatttggct agttgtatgt aaatttacaa ttttatttgc ttttgcagta ctaaagccac
    10261 tgttcatttc ttcttcttga actatatcgt ccatgccact ttcatattca tcttcaatgt
    10321 aatcttcttc ttcatcaact atccaattct taaatttaga tattattcca tttgacatta
    10381 ttaacttcct ccttaaaatt tattcaaatt tgagtaatta ttttttattg tagtttcttt
    10441 ctccaaagat tgatgttcca actctaacaa tggtagcccc ttcctctata gcaatttcat
    10501 aatcgtgact cattcccatt gacaaaacat ccatccctac attagggatg tttagttctt
    10561 ttatttgttt tgataaatct ttaagacctt taaatacacc tcttatctca tcttcatctt
    10621 ctataaaagg tgccattgtc attagaccct ttatttttat atttttatat ttttctgaca
    10681 cttctttgac aaagtctaca acttcttctc tatcaagtcc atgcttagac tcttctttag
    10741 atatattcac ttgtactaag caatctattt ctctgtttgt ttgttctgca cgtttttgaa
    10801 tttcttcgca taatgcaatt ctatctaaag agtgtatcat acaaacttta tcgattatgt
    10861 acttaacttt attggtttgc aaagttccta tcaggtgcca gtttaattta tcacctataa
    10921 tatcatactt tctagctaat tcttggggtt tattttcacc aacagaagtg attccttccc
    10981 tcattgcctc attaactaag tctacatcaa cagtctttgt gactgccaaa agggtaatct
    11041 ctttgctgtc tctatctact ttttttgcag ctttatcaat tttgtttctt atctcagaca
    11101 aattatcttt aatagaaccc attattatca cctactttat ccttatattt gtgtttatac
    11161 tgttaggtct taaaattatt ttgtcatata gattaacact tgtaactcca tttatgtcat
    11221 ttttataata atccacaaat acagaagatt cattctcata agttattcct tctaatatga
    11281 caaattttac actttgtgat tgttcatcaa ttacatatac accacgttta ttgtcttttg
    11341 tttttataga agttttaggt atttttaaac attccatctg attatatatt atatcaaatt
    11401 cttcgacact tgtatcctga tttgcaacaa tttggttact tatttttaat tttaccatta
    11461 ttttattatt attttcatat attttgtaaa cttttgcatc taatttttgc tcatgatatt
    11521 caattattac attttgattt ttttcaaagt tattagaatc ttctttgctg atgtatgtag
    11581 atagataatt actttggtca ttggcatctt tttctatagt tccttttaca tgaatctttg
    11641 catcaacttt ttcatttttt aacaccaacg tatctacatt tttgctaatt atcattacta
    11701 atatattaaa tactaaatat ataagaatac caagtatcac taatctggta tattttacct
    11761 ttttcaaaga ctctccccct ataaaattac tttcattata agtacttctt ctaaaaaatg
    11821 tttattcctt ttttataagc taatatttta cgttctaata attatttttt ccatattaaa
    11881 tttatttttt atcaatcttc ctatacaaga ctgcattatt tatatataat tgtattataa
    11941 agtataagtt taatttacat tttatacgtt aagcttactt tatatgtttt tatagttatt
    12001 tttattttta gatacaatat aaaaccaatt aagatttaaa ataacttttg ttatgttgac
    12061 atttatttag gtaatcattt acgaatcagg ataacgttat cataacaaaa gtttatgtcc
    12121 taaaaaaaat acaaggagga ttttcttatg tcagaaattt tattaggaac aggtttactt
    12181 ttattggttc tatgttgttt cacaattttt agttacaagg ccccatatgg tatgaaggct
    12241 atgggagctc tagcaaacgc tgcatgtgct actttcttag tagaggcatt caacctttct
    12301 ttacttggtg atgttttagg tatggaattt tttagaagtg ttggagctgc taatggtagt
    12361 cttggtggag ttgctgctgc tatacttgtg cctttagcct taggtgtatc tccagtttat
    12421 gcagttttaa taggattatc ttgtttagat ttttctatat tatctggatt cgttgctgga
    12481 tactttgttt ctttcttaat taagtttata gagaaaaaag tgccacctgg agtggattta
    12541 gtggttgtaa ttcttctatg tgcaccgcta tctcgtctta tagcatcaaa tgtagaccca
    12601 ttagttaata gtacactact acaaattgga caagttttga tagaagctac caacattagc
    12661 cctataataa tgggaattat actaggaggt ctaataacag tagttggaac gtctccactt
    12721 agttcaatgg ctcttacatc tataattggt cttactggtc ttcctatggc aataggagca
    12781 ttaggtgctt ttggttcagc ttttatgaac tcaacactat ttgcaaaatt gaaattaggt
    12841 tctaaaaaag atattatatc tgttgctatt gaaccattaa cccaatcaga cataatttca
    12901 gctaatccaa tacctatata ttctactaat ttctttggag gagccttttc tggtatcatt
    12961 gtagccttga tgggtcttgt aaacatgaca ccaggtacag ctacacctgt ggctggtttt
    13021 gctataatgt ttgcttataa tccagttcaa caagttctta taacagctgg tttatgtgct
    13081 ttattcaatg taattgcagg atttttaggt tcaaaaatat tcagtacctt taaagttctt
    13141 actgctggtg aaatacgtgg tactgatgta gaagaagaaa ttgcttaaaa aacaataaga
    13201 tttataaatt tatatctcaa gtagtagagt tttatattgt aggcaatttt attaattgca
    13261 aacgttttat tttttattta tgtttatgat tattatgtgt gttgaatatt tagataaatt
    13321 tttatttatt atttttattt agatttttgt ttagtttttt atttggttga tatattagga
    13381 ataaaaatta gtatagttta ttactagtta gatggcataa ctttttagat acataaaaaa
    13441 ttttatatta attagatatt attaaaataa aagcgataca tgaattttta aatgtccatg
    13501 tatcgcttta tttttgccat aatcttaata actgattttt aaagtttatt atcttaacaa
    13561 agttcattat cttatataat atttaaatgc ataggcttct ttaatttaac catctaaata
    13621 tttaattaaa cattattata tgtaatataa ctaattttta aatgaatgta taggagctgg
    13681 aatccttcct cctctttgag taaataattc agatgaattt gtatttatag gcattactgg
    13741 tgctcgtcct aaaagtcctc caaattctac catatcacct acatcacatc ctggggctgg
    13801 tataattcta acggctgtag tcttattatt aatcatacct attgctgcct catcagctat
    13861 catggctcca agcgtacctg ctgtagtatt tcctggcaca gctatcatat caagacctac
    13921 agaacaaata gcagtcattg cttcaagctt atctatactt aaagcacctt taataacagc
    13981 atcaatcata cctgcatctt cagatactgg tataaacgct ccactaagtc ctccaacatg
    14041 tgaacatgcc attactccac cttttttaac agcatcattt aaaagtgcta atgctgctgt
    14101 agtcccatga gtaccaacaa cttcaagacc catttcctct aatatatttg ctaccgaatc
    14161 accaatagca ggtgtaggag ctagtgataa gtctattatc ccaaatggaa catccaatct
    14221 actagaagct tcctttgcca caagttgtcc aactcttgta attttaaatg cagtcttttt
    14281 aactgtttct gaaacaacat caaaaggctc tccctttact ttctctaaag ctctcttaac
    14341 aacaccaggg ccacttacac caacatttat aattctatca gcctcaccaa caccatggaa
    14401 agctcctgcc ataaatggat tatcttctac tgcattacaa aatactacta attttgcaca
    14461 accaaaacct tttgcatctt ttgttaattc tgcagtttct tttatgattt ctcccatttc
    14521 tttcactgca tccatattta taccacatct tgtagaacct acatttactg aagcacatac
    14581 tttattagta cttgctagag cttttggaat tgacttaatt agtatcttat caccttttgt
    14641 atatcccttt tgaactaatg ctgagaatcc accaataaaa tctataccta aatcctctgc
    14701 agccttatcc aatgtctgtg caaactttac atagtcattt tcatctgttg cacctgcaat
    14761 aatggaaatt ggagttactg ataccctttt atttacaatt gggataccaa attcacgctc
    14821 tatatctttt ccaaccttca ccaaatcttt agcagaactc ataatcttat tgtatatttt
    14881 ttctctagct ttatctccat cagggtctat acaatctaat aaagaaatcc ccatagttat
    14941 agttcttata tccaactgtt cttcatctat catctttatt gtttcaagta tatttcctac
    15001 attcactatt atcacctccc cttactgtct actacagatt atgcattgaa ttaaatattt
    15061 cttctcgctg aatttttaca tccactgata atttcttacc tctttcaacc aagtcctcaa
    15121 ccgttttctc aaaagaattt aatgatttct ctaaatcaac tatcataatc atagtaaaat
    15181 aatcctgtaa tattttttgt gatatatcta ctatgttgat attttgcttg tataattcat
    15241 cactaattcc tgccactata cctggtttat cctttccaat tactgttaaa attgctttca
    15301 taataatatc ctcccttatt tttttataaa tcttatattt ttacaaattg aactatgtgt
    15361 taacatatat ttcatttatt tgttagtaaa ccacttttta tgtatatatt taatatattt
    15421 taatacctat acattcattt gtcaattttt tttcaatatt ctattatttt tatactattt
    15481 agaaaattca tatattatat atgttttctc aacaacaaat acagttttca taataatgaa
    15541 aggtattact tagcaatctc atgattttct aaataatacc tttctaaaaa ttattttttt
    15601 aattttatga atttaattat actttttcta gtatcaggat ttacaattaa tatagaacca
    15661 atcataattg gtgttagtat acaaaataaa aaaataatat ctttttttag attatattct
    15721 ttagattcta atttataatt attatttatt attccatcat aatcacttat atttgactta
    15781 tttttatttg tatcttgatt tttgttagaa atactttccc tataaggaaa agaatgttca
    15841 ttggtaccaa atactgattt tgagcttaaa tcataattat catcattttc tgtaattgaa
    15901 tttttattgt aaaatccttt ttctttatca gaattatttt ctttattacc gtctttaggt
    15961 atatcatgag gatttttatt ttcattgcta tcagtacttg attctacatc atctttagga
    16021 gtatttggtt gtttctcatc agaattatca ttttcattat tattgttttg attgttatta
    16081 ctatcattat tttcatttcc attattccca tcttgattgt tatcatcctc atctctatcc
    16141 gggtcgtctc tacctcctcc tccacggtca ccatcaatat catcattttc ccgttcatca
    16201 tctggtgtct cttggttgtc tccgcctccc attataaatc ctggtttaaa aactatattt
    16261 gaataccctt cttttaatcc tcctaccact tttactctaa aacaacgcaa cttaaaatct
    16321 tcaaaaaaaa gtatagcttg atctctaata tcctcctgtt cttcagatat ccaattgatt
    16381 ccatcgcttg aatattcaac aaaaacctta cttgcactat acggcatatc ataaaataaa
    16441 acagctacat atccattttt tgtattttga aattccagtt ccaaattgtc tattggtttt
    16501 ttctctataa cagatacatt caaaatagga actacatcat catttattat aattttttct
    16561 ttatttaaca tttctgtttt aaactttcct gttatattaa aattttctcc cttttccaac
    16621 ttttcataat aatcagtaaa atcccattct acatctatat caagtcgatt accactagat
    16681 gtttctaata ccatatattt gggaaatttt atattttcta ttttatcatc tttacttact
    16741 tttatttcat cactaaatac accaattccc ctatgacaac atttcacaat attatagcca
    16801 gaatcttcag ctatagaggg tataagctca ttataatcat caattatata aactttctta
    16861 ctttctgata taattgattg tgccaactta ttattatctc ttagtaaccc actttcattg
    16921 ttgctactat atgcttttat tgaagtttct tctatctcaa catcaccttt agaataaaca
    16981 cctatagcat gttctccatt cacttcaata tccttattta gtattctaat atcattttca
    17041 gtataaattc ctattgcatc ttttccattt gcctttattt tttcaacaga ttcgtaggat
    17101 gatttaatat gtaagtctcc tccttcttca acgtataagg ctgtcccatc agtagcaatt
    17161 atgttgttta taccaatact tatacttcca ccattttcta tatgtattac tccttctttt
    17221 cctccttcac ctattatatt caattcatta tcatcaataa taaatctccc atgatttttt
    17281 atcaatattt tatatttgtt ggtatctatt gtaaaattac tgtcataagg aatataaaat
    17341 ctaaactctt catctattac catatcacaa gaaagagtat aaactatttc ttctttatta
    17401 tttttatttt cttgaaccca cctttcaaaa tcttcaagac aattttcctc ttgtccaaaa
    17461 actttatgtg gaaaacttat aaaacacaaa actattatac tcataaaaat aaatatctca
    17521 tactttttca tcttacactc ctagaaattt ttagctttga aacaatcctg tcgaaacata
    17581 tacttcaccc actataattt ttccacaatt atcaattatt gtcaatttat ataagtatgt
    17641 ttattaattg ttataaataa aaagctactt actaaagcaa acagacgttt cactttaata
    17701 agtagctata tttttataac aaaatagtta taatattaga acttccttca tttacaattt
    17761 tttgtaaagt cttttgcatt ttaactctta tctcttctgg catagtatat aatttacttt
    17821 gtaattgctc ttttactaag tcatgtagtg acttaccaaa catatttgat tcccataaat
    17881 ctgctggttg ctcttcaaat acttccataa gatattttat catctcttca ccttgatttt
    17941 gatttccaac tattggagaa acctctgtag atatatctgc ttttataata tgaagtgatg
    18001 gtgcattggc ttttaacttg ataccatatt gttttccttg tttcattatt tctggttctt
    18061 ccagactaag ttcttctaag gaaggagcta ctactccata tccttttatc ttggcatcta
    18121 ttaaagcact ttctatttta tcatactcat ttttaacttt agatagtcta gttatcagac
    18181 taagcagttg ataatctcct tcaattttaa atccactttt ttcttcaagg acattataga
    18241 ataaatcttg ctttgtctgt aaatcaatat ttataacacc ttctcctagc tctacattat
    18301 caacacctgt atcttccaaa aactctaact cagaaaatcc ttgtataata ccttctatat
    18361 cccttatttt acctatatct ataatacttt gttttaatgt tgttattatg ctacttttta
    18421 tccaatgatt tctttcaaga ccttcaaccc attttggtaa gttgattctt atttctgtaa
    18481 gtggaaaatc atataataca gcttccataa cctcctctat atcttcttct tccatttcaa
    18541 ccacattcat tggaagaact ggaacttcat acttttcttc caattcactt ctaagcatac
    18601 tcgtttcctc actttttgga cttaacgtat ttaaaaccac tgcaaatggt tttttaagat
    18661 ttttcaattc ttgtataact ctctcttctg gttctacata gctttttcta tcaattccag
    18721 taactgaacc atctgtcaag acaactatcc ctattgtaga atggtctttt ataacttttt
    18781 tagttcctat ctctgctgcc ttttcaaatg tcatagcttc ttgtgaccaa ggagtggata
    18841 ctaatctttg ttttccacct tcctcatgcc ctaaagctcc ttcaactatg tatccaacac
    18901 aatctaccat tcttactttt aaagatactg tgtcttttat ttttatttct acaccatctg
    18961 ctggtacaaa ttttggttct actgtcatta tcgttttacc tgaaccactt tggggtatct
    19021 catctcttgt tctatccttt ttaaattcat tgtctatatt aggtataacc aacttttcca
    19081 taaattttct tataaaagtt gattttcctg ttcttacagg tccaactact ccaatatata
    19141 tatccccctg agtccttttg gatatatctt cgtatatgtt attattcata ttattcctcc
    19201 tatacatcta atcttattaa attatattta gagttaaggg ttaatattct taaaatagaa
    19261 aaataaagac cagcaatatt aatttaattt acatatagaa atttgtaaat ttcaatgtaa
    19321 attaaattaa tattgctggt ccaaatagta gtgtattata ttaactgact ttagtagcat
    19381 tttcatttga attattattc atctcaataa gttctttacg tctttctttt gtcatgttca
    19441 tccatataaa tgtaaacacc aatccaatta tggctactat agtaagaact atgaagtagt
    19501 acctatatcc agttacaccc ggaaatgcat ccaatatctt ccctgctgct aaaggacaaa
    19561 gtacttctgg aagatatcct aacgtagcaa ctattcctat agcagttcct gatattgata
    19621 atgaataatt accttcttca agtaacgaat agtgtaaacc ttgaattgca tacatagata
    19681 catatattgc aacacatcca atcaatagta tataaaccat agatgatttt gttggtgtaa
    19741 atattacacc taaaagacct gcaatcataa gtataaatcc ataagatata atctttgatg
    19801 aaccaacttt atctccaagt aatccagaag cagctgatgc tattggtcta caatactgag
    19861 ctaatattga gattgcagat gcaaacacca cagtagctcc aaatgcttca gttgaataag
    19921 gcgtaaaata ataaaatgac atattagctg aatatgaaca aaacattatt attgttatta
    19981 tccatgtatg aggcattttt attactgcaa aaaaggcttc tttatcaaat tttgctgata
    20041 cctctttttc attatccttt aatttgaaaa atactaatac tccaactatt acatttatta
    20101 ctgagtataa tactataata gctgtaagac cagatttatc acttactttt gatgaaatat
    20161 acccaaatag tatcaatact agagatagat gaattgcatt ggtaattcca cgaccacttt
    20221 ccataaatcc aaaagctttt ccttgttcat tttcagatgc taacattcta acagctttta
    20281 caagagctgg ccaaaaagta agtattgttg ttattcccca taaggcatgg attaaaaaca
    20341 caacaatata tggaggataa agtgttaata caagaccaga tattcctgta ataattaaag
    20401 aacctgaaag caattttctg gctgaaatac ggtctgctaa aaaaccacca aaaaggtatg
    20461 ataccattgc aagtagacca taaatgcttc ctaagcttcc catttgtgta tttgtaagat
    20521 taaatgcttg tgcaaaagta tcataataat aattctttaa atacggtaaa gcatatataa
    20581 atgctcctgc tacaaagagt attatcaaga ctttgaaatt tttccaaatg cttggtttat
    20641 ttacttcaac tgacatactt cctccttatg taaatacctg taaattttca tgataattaa
    20701 ttattgctta ttgtattgtt tattcaatat ttcggaatat ttattaatat attaggttaa
    20761 tctatcaata atttatggtg agttatgagc taaaagtaaa ctcttttagc tcaccataat
    20821 aattatattt ttatttatac taacgtccag agttattaga tatctttttt tcatagttct
    20881 tccatagcat taaacctgtt attataacaa aaagacctcc tcctatcatt tcaatctcat
    20941 agattatatt atcttttaaa gtctccataa ctggtgccgt tgagaaaagt atgccaacta
    21001 cagttactac aagtaccatt ctggcaatat tgatacaaac tgaatcactt tttgcaattg
    21061 aatatggtct ttcttcattt ggtcttgtct ttctaagtct aatataagat gtaaaaagca
    21121 agacatatgg aaataatgct gttaatgctg tcatagtaac aagaacattg tatatattat
    21181 ctactgatgg taataagttt gttcctacaa gaagtagact cactattata gcctgaacta
    21241 ttactgcatt tgatggtata ttgtatttat ttgtaacagt caattgctta ggaaatacac
    21301 cttctcttac atttccaaaa agcatcttta ctggacctgc tatataaagt attaatgctc
    21361 ctagtactga taaagttatt ccaaatgcta ctattcttat aaaccaactt cctataccta
    21421 aatcttgtgc aactttagct aatgcatcta gtatccctgt agatgctgca attttatctg
    21481 gaggaagtat cattgttatt gctactgaac ctaagatata gattcctcct attaaaacag
    21541 ccacagttaa tatagcttta ggaaagtttt tcttagcatt atccatttcg gttatgaaat
    21601 tagcagtcgt ttcagctcct gataatgcaa atattatagc agatatagaa actaatgaat
    21661 tggcatctat ttttggtatt atattttgga ttgtatatat cgatgctgat ggagcttttt
    21721 tgagaataac tacagacata aatgccatca ctataagtaa tatagcagga attgtagaac
    21781 ctaatgctcc tgtattcgta aaaaattttc caaatgccat cccacgagta cttactaagg
    21841 acaacagcca aaatattatg agtgaaagtg ctaaaataaa catcttattg tttgataaat
    21901 ctggatttcc aagcatatat gcaatattta tcgctaaaaa agtcaagaaa gaagaatacc
    21961 aaaatatctt tgatgtccaa tttagccatg acaccataaa tccccacttc tctccataag
    22021 cttgtttaac ccattctcca agtccaccat cttttggata tgttgcagcc aactctgcac
    22081 atataagtga tgcaggaaca aagaatataa aagcaaacaa taaccaaact ggtatagaac
    22141 caagacccaa tccaaaacta gaggcagtag atttagctat ccatctaatc ccaaatagtg
    22201 ctgatatatt cataaatact aaatcccaaa atccaatttt ctttttcact gtaattcctc
    22261 caatttcaaa tttattcaga ctcatacaca atgtattgac ttaaatatca agtataagtt
    22321 cttcaacact tcttggataa ttagttataa ttgtagcacc attcttacct actattgctg
    22381 tatctgagtg tctaaatcct ccaactccag gtatatatat ccctggctcc atagaaaata
    22441 ccattccttc ttctaatatt aattcattgt caaatcttaa atatggctct tcatgttctg
    22501 ataaacctaa accatgacca attctatgat ttgaatataa ctctagacca tactttgcaa
    22561 caacagctct tgctgcttca tccaccattc ttgctggtat accagctttt attgtatcta
    22621 atccagcttg ttgagcctct actgcaatct taaacacttc tttttgtctt tctgttggtt
    22681 tgcctataat aaaagttctt tcattttctg ctctatagtt ttcataccaa acctgtctac
    22741 tatgtattac tatatctcct ctttgaagta ttctagtatt ggaatctaaa tgaggttgtg
    22801 ctgttctatc aatccctgaa caagtccagt ttgcaaatcc tatatatgta tcaggataat
    22861 tttcagaaac atattttagt aaagcattat cccctgcaac gtcaaactcc aattcactca
    22921 tcccaactct aacattttct aaagaccctt ttattcctat atcagatagg taacctgcta
    22981 tcttcaaaaa ttctatttct tttgcatctt ttacatatct catttcaaat attttacttc
    23041 caacatcttt gatagcaaat gacttatcag ttatatactc tgaaaagctt gcagatacta
    23101 tatctttttc tattccaaca gttgttcctt tagggtattt atttaaaatt atatctaagt
    23161 aatgtttatg tgatattcca tgttctttca tttctggtat ttcataatac acatatacat
    23221 tatcaacttt tgcaacttct ttagcatgta attcttctaa tccaggtact attaattcta
    23281 ttttatcttg agttactact gttacaattg gtctagaata agttattgct ttaaatccac
    23341 taatataaaa ttgattgtct ggttcaaata ttaaagcaat ttcaatgctt ttttcattca
    23401 tgtactttct caatctttct agtctcatat tatttgacat aatgcacctc tttcttaata
    23461 ttcagataat ttattcaata caacaaggat gaatatatta ttttaaaatt cttaatattt
    23521 ttagtacttg tcgtatttgt atgtaaatta attttatttg tgattatttt atcataatca
    23581 tgattatttt gtcaatcatg attttatttt aaaaaatttt ttatattcta gtgattttaa
    23641 attatctaaa atataacgag tatacattgt attttgtaat attattcttg atttatggta
    23701 agtttaatga taaaatcacg attatataaa ctatattgat tatttgtagg tgaataaaat
    23761 gacaaataaa gaattacaaa agaaaaggat attgatgtat ttcatagaag ctgctcaaaa
    23821 tattatggaa aacgaaggta tagaaaatat tacacttcgt aaggttgcag atatggctgg
    23881 ctataatagt tcaactctat ataaatactt taaaaattta gaccatttaa tatcatttgc
    23941 atctataaaa tattttaaag attataactt gaatatttca agatgtatag aaaatgtcaa
    24001 tgatgaatat aagaaatata taattatgtg gaaattattt tgtaagcatt cttttgataa
    24061 tgctcaagct ttttaccagg tattttttaa cttgtctagt gatgaactta gctatataac
    24121 aaaacaatat tatgatatgt ttccagaaga tttaggtatt catgatagtg acatatcttt
    24181 aatgattaca ggagaaagta taaaggaaag aaataagata ctattaaaca atcttgtaga
    24241 tactggatat ataccagcta aagatttaga cataatcaat gatataatta tttcttttta
    24301 tcaaaatcta ttattcttaa aaaagaacac aggaaaaaat tctgatgatg atgaattaac
    24361 tatgaaaatg atttcttcta ttgaatacat aataaaacat gctaaataaa attaaaatat
    24421 ggctgtctca aaatagagat aagccttttt tattgttgaa ataataaaaa tatatttaat
    24481 ttcatataaa aaagagtgcc tcgtaaacta aaaagttcat tttgagacac ccctaaaata
    24541 aatttattat ttattataca atagtttata tatcatcacc taaaactact tcttccattt
    24601 catgcttttt acttctcatc attagttcta ttccaacttc tttaggattt gaacctttct
    24661 ttattacaga atatatagca ttagttatag gcatatctat atctaatttt tcagcaacat
    24721 catgtgctac ttcagtagca gttatgcctt ctacaaccat ctttacttct tttaaagtat
    24781 cttctaaact catcccttta cctatgagta taccagctct tctatttcta ctatgcatac
    24841 ttgtacaagt aactattaaa tctccaatac ctgaaagacc tgcaaaggta gacatattag
    24901 ctcccatagc aattccaagt ctgctcattt cactaatacc tcttgtcata agggcagctt
    24961 ttgcattatc accataccct aatccgtcac atatcccagc tccaaatgct ataatatttt
    25021 ttaatgctcc tccaagttct actccaacta tgtctggatt cgtataaact ctaagtttag
    25081 ggctcataaa taaatcttgt atcatctgtg ctatttttaa atctttagaa gcaactacta
    25141 cggtagtagg aatatccctt gctacttctt cagcatgaga tggcccagat agtattacat
    25201 atggattttg tggtaattct tcttcacaga cttgagataa tctaagccca gtcccttttt
    25261 caagaccttt agctacatta acaataactt gtccttcttt tataaatggt tttatttttt
    25321 ggcaagtact tcttacagcc tgtgatggaa ctgctaaaac tattacctta caatctttta
    25381 tagttttttc tatatcagta cttatagtta tattatttgg aaataatact cctggtaaat
    25441 agtctgtatt ttctttagtt ctgtttattt ttttagcttg ttcctctttt cgagtccaca
    25501 tgctcacatc attacctttt tttgcaagcc ctaaagctaa tgcacttccc cagcttccag
    25561 tacctaatac acatactttc tccatgttta acaccacctg agtataatat atttactatt
    25621 ctttcttttg accaattttt ctctctgtcc catttaataa tcgctttata tttgctctgt
    25681 gattatatat tactgatgca gttaagaaca gagctactat taaaccagct ttatttttta
    25741 ccataatcat aaatattggt gaacatccta ttcctacaac agaacccaat gaaacatact
    25801 ttgttatagc taccaccaat ataaatactg ctagacacat tagtgttatt actggattta
    25861 cagctagcat tgcccctagt gaagttgcaa cacctttgcc tcctctaaat cctaaaaccg
    25921 ctggccaatt atgacctgct acaacacata taactgccag atatccagct aaaagagtat
    25981 ctattccaac caatcttgct gcaaattctg atattaaaac agccattaca cctttaagaa
    26041 catcacctaa aaatgtcatt gctcctgctc tttttccaag tgtcctaagt acatttgtcg
    26101 aacctgcatt accagaacct tgagtcctta tatcaacccc agcaattcgc tttgcaacta
    26161 tgtatgaggt agatatattt cctaaaagat atgcaactac agcaataatt atataactaa
    26221 atatctccac tgaatttccc ccctttagtt atattttaag atatttattt tttatttttt
    26281 tgtctatact caaactttat ggaagttcct tcaaatccaa aattttctct tatcttattc
    26341 tcaaggtatc tttgatatga gaagtgagtt aaatccttat catttataaa caatgtaatt
    26401 ttaggaggtc taatgtcagt ttgagtccca tagtaaattt ttaatcttct acctttgtca
    26461 gatggtggtt gatttaacat tacagcttct ccaattactt cattcagtgc tgaagttgat
    26521 attctcttag aatgttcatt tgacacatat tcaactgtat ctagtatctt gttcattctt
    26581 tgattagttt ttgcagaaac aaatacgatt ggagcataca tcataaatgg aaatttttct
    26641 tttatatctt ttgtgtaatt actcatagtc ttattatctt tctctattaa atcccattta
    26701 ttgattacaa atatgcatcc ttttccttca tcatgtgcta tacctgcaac ctttgtatct
    26761 tgttctgtta caccttctaa ggcatctatt actatcaata ctacatctgc tctatctaca
    26821 gcactcatag ctcttattac actgtatttt tctattgtct catatatttt actttttctt
    26881 ctaagccctg ctgtatctat tagaagaaat ttctgtccat ttttttcaaa ataagtatca
    26941 attgcgtctc tagtagttcc tgcaattgga cttacaatta ctctttcttc tccaagtatc
    27001 ttattgagta tagaactttt tcctgcattt ggtttacctg ttatagctac tcttattata
    27061 tcttcttcat actctgtatc taatcctgct ggaaaatttt caactatctc atctaataaa
    27121 tctccaaatc ccatactatt ggctcctgaa actgcaaaag gcgttccaaa tcccaactca
    27181 taaaaatcgt atatattatc aaattgactt tgactatcaa tcttattaac cactaagatt
    27241 actggttttt ttgtctttct aagcaattgt gcaatttctt tatcagcagc tgttattcca
    27301 gctttaccat caactataaa aagtattaca tgtgacatgt ccattgcaag catggcttga
    27361 tttctcattt gagataatat tatatcttcg ctatcaggtt caattcctcc tgtatccact
    27421 aatgtaaaat atttatctaa ccattctact tcagcaaata ttctatctct tgtaactcca
    27481 ggtgtatttt caactattga tatccttttt cctgcaaatt tattaaatat tgtagactta
    27541 ccaacgtttg gtctcccaac tacagctaca actggcctac ttatactcat tttatttctc
    27601 cttccatctt ttgttttcta ttttaaaatt ttatccacaa aatcttttcc ttcattcaaa
    27661 caagggataa tttttattct cataagttct tctaattgat ttaattcaat attatctaag
    27721 aaaatttctt catctgcttt tagcatactt cttgttatat aaagagcttc tcctaattct
    27781 ttatcttcaa gttgttcttt taaatcctta gctgttaaaa gacctgatac agttattgtc
    27841 tctccaaaaa acttgttttt gatttcatat acatttactt gaagattttt aaacttgtcc
    27901 atcatagcat ctgccatact ctgtataaat tcatatgcag aatgaccagt agctattgat
    27961 actttcttct ctctttttag aatattctca ggcaatatat ttagatactc ttcaatctct
    28021 gtttttaact tacgtatcat acctacacca tcttcaaact gtaaaaaacc ttcatattct
    28081 tcatatccag gcaattcact attagatagt atataaaatt catctgataa aaatgcaaat
    28141 cgagtaccta atttttcaag atatttctgt tgtatttgat gtatttgctc tatagtttta
    28201 cttgcgctct tatcattaaa tatatttaat tctactagat tttctctatg ctttgtaatc
    28261 ccaactggaa ctatcgcaac actgtttaca tacggataaa gttgagctag ttcttttatt
    28321 gttctatcca attcctttcc atcatttata cctggacata aaacaatttg acagttcatt
    28381 tctatatgag catctgccaa tctcttcatt ataccatata atttccctgc aaatttattg
    28441 cttatcattt tttgtcttaa ctctggatta gttgtatgca cagatatatt tataggactt
    28501 attctatatt ttataatatt atttatatct tcttcactca tatttgtaag tgtgacaaaa
    28561 tttccttgta aaaaagataa tctcgaatca tcatctttaa aataaagagt ttctctcata
    28621 ccttctggca attggtctat aaaacaaaac atacacttat ttctacagct tttagcttgg
    28681 tcaattatcg gatttgtaaa ttcaacaccc aaatcttcat catagtcttt ttctatctcg
    28741 tatatgtaga cttcgccatc ttttttttgt atttctacat ctaaatattc atcacttagt
    28801 aagaatctat actctattat atcatgtatt ggctgttcat tcacagatat aagtaaatct
    28861 cctacctcta tacccatttc ttctgcaata ctatctttat aaaccttact tataatatta
    28921 tttacttttt ttacatttac ttccaatatt ttcaccactc ttttgtattc atcaatgctt
    28981 attataatgt attttaatat gcaatttatt tatttattat attttatgat agcattttta
    29041 agcatttcat gtcataataa cacattttaa ttctaatagt caatataagt aaatagctat
    29101 aaaatagatt agaacaaata atattcaaat ttaagtttct taaaaattta aatattattt
    29161 gttcttaaaa aaattttata aatttaatgt tttactatga ttaacgtccc attagtcata
    29221 tcatgaacca ttccacctac acactttgac atcaacaatg ccttattttg taagtctttc
    29281 tcatcatttg cataaaatat tggacaacct ccaccatttt tcatattctt atcaagtgta
    29341 actatagcta gggtatattc atttaaacct atatccattc ccatcttatg cacttccttt
    29401 ctttcctatt ttataatttt ttagtgataa gttttttcct ttagaacttg aaagtattgg
    29461 gcatgacttt acggcttcca ttactttttc tacattttta tctactggta aataagcaat
    29521 cattatactt tcattctctt tattccttct aggtaatggt acgaatgaag gttctccata
    29581 atctccatat aaacctaacc ttgaatatat attgtatact attgcttgtc tttgacctga
    29641 atcaaataat atccctgcat tagcataatc tttattttta ggaattattt gtattcctac
    29701 acctctatta atatatactt ctctatcact ttttagacct atatttgtta ttccctttaa
    29761 atctcctacc ttcaatatag actcatctac aaaactaatc tcagcaggca ttacatcagc
    29821 tatgtctcca atactttttc tagtaagaag tttttttaat ataaaggcta acactaatcc
    29881 acaaattgaa cttattacca aactcattcc ttcacttatt ttcgtttctg caagtattac
    29941 ataatacaat cctattgtta aaaaagatgt aactatacac atataatttc ttacttcata
    30001 ggttctagct atctcttcta tgaatgcagc tcctctcttt acaagttgaa cttcctctaa
    30061 gttttgcaat gtatttcttc tatttgctct cacttgtcta aattgctctg ctgctaggga
    30121 taaaaaagtt atagatgtat aagaacgatt tataagagct ggaaccaata atgctcctaa
    30181 tgaagaagcg acgaatgcta atataagttg agatagtaaa acatttggtt gcgttggata
    30241 ctgtttttgg tctaaattca acattataat tctagatgtt ataccaataa taacagcaac
    30301 aaaaaatact ctatccatta aatcactcct aaaatattta atttgaaatt ttacatgtaa
    30361 atctacaaag tctttctaga aaaatcactc tgctttcctt ttgatgtttc tatgataggt
    30421 gtacttttca ctacatctat catgacatct atatctttga gtattggcat atatggtata
    30481 accacagtac ttttttctaa attggtctta gatatagcaa caatatcaac ctcatctaca
    30541 tctctatcta tccccatatg aataaataga ttatgtatta tagcttgtct ttgccctata
    30601 tcatttacta ttccaaatgc acctaaatct cttggtataa cttctatagc cagacattca
    30661 tttctatact tttctcttgt actttctaga cctatgttag ttattattac accatttacc
    30721 attaaaatag gtccttcaaa acttattttt gcaggaacta tatctgctat atctgctata
    30781 ctgttccttc ttaaaaatct tctaaaaatc aaaccaacga tagctcctga cacaatagct
    30841 aagattgtgc aataaaaaaa gctaaggcca tactttcttg caaaaacgat ataaactatc
    30901 gaagatacca gtgcagaaaa aagacttata taacttctag attcatacgt agatgctatt
    30961 tcttcaacgt aagcgtctcc ttttggtact aattcttcat tatcgatatt ctttagtgtt
    31021 attctttctt gttctgcaag accttgaaac tgttgtattg ctactgcaaa aaatgtcaag
    31081 gctgcaaact ccttatctat aagtgcaggt aatgctatag cacctaacga agctgaaagc
    31141 ccagatataa ttatctgttc taaataatct tgtggtcttg atgggtattg tttgtctgta
    31201 actcttaaaa ctaatcctct acataatatt cctacaacta atgcaactat aaaagagtgt
    31261 ctaaataaat ttgcattcaa taaactttct tccattttct cagctccttc tcttatatag
    31321 tttgtgcaaa aaacaaaaaa aattcccttc tatttaagga aatttttttg taatattgta
    31381 actataaatt cgctaccaat gccaagttca ctttttactt ttatacatcc atttagtgat
    31441 ttgactatat gctttgttat agccaatcct aaacccgttc ctcctacatc cctacttctt
    31501 gctttatcta ccctataaaa tcgttcaaat atgcgttcta catcttcttt tggtatccct
    31561 acaccattgt ctataacttt aattacgatt ttttcttcat cttttaacac tacaacttgt
    31621 acaatcccat tatcttgggt atactttata gcattatcaa ctaggtttaa gaacacttgc
    31681 tttatatagt ctttattgga tagtatactt attgatttat catcacattt atataaaact
    31741 tctatatttt tttcactagc tgaatgttga gttatttcat atacctcttt aaatacatca
    31801 tatactacaa cattttccat aagaagagta tctttatttt ctacaaatga taacaacaat
    31861 atatcatcaa tcaacctttt taatctatct gattcgcttt ctattatttc taagaatcta
    31921 tttctagtat tcacatctat attttcattt gactttagtg tttcaacaaa cccacttata
    31981 gatgtaagtg gtgttttaag ttcatgactt acatttgcaa caaaatcact tctcatattt
    32041 tcaagtttaa cttttttagt aatatcttct atatttacta tcgaacctat tattacgttg
    32101 ttagtattct gaagataaac tgggtctact tttatcttat atacgatatc atctttagta
    32161 gtaatattag cagtttcatt atctttagaa ccaataaatt gaagtatttg ttttaatatt
    32221 tcttcttctt ttattacaac attaatatta tgaccttcaa ctaattgatt tggttcactc
    32281 tttatcattt cttttgcttc atcatttatc agaagtatat ttccatttac atctatagct
    32341 aaaattccat gagatatact ctttaatata gaccttaact gtaaatgttt atactgtact
    32401 tcttctaagg ttttatccat attctttatc atatgattaa aatttctagc taattcgcca
    32461 agttctcctt tggctgatat gttaagccta gcatgatatt cattattact tacttttttt
    32521 gagacatata taaactcttt taaatatttc cttaatgtta ttgtgtatct tacagctaat
    32581 ataacaatgg ctatggacaa cataacaata aaaaaatata tactatttaa atcttccaca
    32641 agataacact cctaaaatat aaccttttta atctattttg tatcctacac ctcttatagt
    32701 ctctatatat ttttccgatt tatcttcatc ttctattttt tttcttaaat atcttatatg
    32761 aacatctact gttctagttt ctccatagta ttcatacccc catattttat ccaaaagata
    32821 atttcttgaa agtacttttc ctttattttg aattaataat tttaacaatt caaattcctt
    32881 aagagttaac tctatctttt cagagccttt ggtaacttca tgttttgata aatctagttt
    32941 taaattacct gtagtaagta tattgttttc ttcacctaag ctagtcaaat tatatctcct
    33001 taaaacagaa ctaatcctag ctaacaactc ttttatacta aatggcttag ttatatagtc
    33061 atcagcacct atttcaagcc cttcaacctt gtcattttcc atatttttag cagtaagcat
    33121 tataacagga atatttttta agtccttatc acttcttatt tttctcaaaa cttctattcc
    33181 acttatattt ggtaacatcc aatctaaaag tattaaatct ggtttaattt ccttagcctt
    33241 tataaatccg tcaaatccat catatgaata actaacttcg taatttgaca cctccaaatt
    33301 gaattttaat agctcaacta tatgcatttc atcgtctata acaagcactt tagtattcat
    33361 taaaaagctc ctctctattt tatctgtagt accgttccta ttcgttctga tgccttatta
    33421 tgttttctat aagagtggaa tttatctgct ctacaactag tgcataaatt taaatttatt
    33481 atattttctt ttttaactcc actacatcta agcatatact cattaatttt ccataaatct
    33541 aaatagtaac ttccctcttt tattatatag aacttttcat cattatttgt aagaattgtg
    33601 ttaaattttt ctactaaatc ttcagacact tcataacaac atggtccaat tgatggccca
    33661 attatacata ctaaatcttc aggaactgtt ttatagcatt cagacattaa ttttattgtt
    33721 ttatgaccta tattactaaa agtccctctc caacctgcat gagccagtcc tatggcttta
    33781 tttttagcat ctataattga tataggtaca cagtctgctg taaacagtaa aagtggtact
    33841 ttttccaagt ttgttataag tgcatctcca tctcttcttt tccctatagt atctttattg
    33901 actatattaa ctatatctga atgtatttga gaattactag ttagattttc aaatgtcaaa
    33961 tcacattctt tacatacttt taacatatct tctctatttt ttgcatctat attcttacat
    34021 gttataacta gatttacaga atttaatttt tcatcaagtt cttcacaatt accacttaaa
    34081 ttaacatact ctttaatatc ttgtacattt tttatattta tataatcttt catcatttgt
    34141 ctcctttttc tatcagtata cttttaagtt catttacaaa agtatttata tctttaaatt
    34201 gtctatacac agaagcaaat cttacatagg caacctcatc taactctttc aatttatcca
    34261 ttaccatctc accgattttt ttggtttcaa tttcttctat aaaacattta tttatttcat
    34321 tttcaatatg tacaacaata ctttcaatct cgtcaataga aacaggtctt ttttcacatg
    34381 cttttagcaa tccatatttt atcttttctc tatcaaaata ttctctacta ttatcctttt
    34441 taatgaccat taaaggagtt gtttctattt tctcatacgt agtaaacctc tttttacatg
    34501 attcacactc acgtcttctt ctgatagatt ttaaatctgt atgtctagaa tctattacct
    34561 ttgattcttt ataattacaa taaggacatt gcatctatat tcctcctttg tttaactata
    34621 tctcaaactc atctaagctt aattctgaac ctatatttac tattattgta tcacaaccta
    34681 ttttaagtat atcattccaa aatataactt cttcatcccc tcctcttgaa aaaaaacttc
    34741 tacttccatc tccaaaaatg gtaaatgaga ctaccttacc ttcgtgaata tccatgtcta
    34801 tgtctattat aaaccccatc ctttttccat tttttacatt tataatttct ttttccatta
    34861 tatcagaaac tctaatcata ttgtactcac cctttcttta aaaataaata tgtatcgaag
    34921 taaaaaaaaa tgacctatat aggtcattta aattaaaata atgtttacag tccatggatt
    34981 acttatacat attttctcat attctttaaa gcattttttt caattcttga tacttgtgct
    35041 tgagatatac cgatttcatc agcaacttct atctgagttc ttcctttgta aaaccttaaa
    35101 tctaatacca acttttctct actatttaat ttcttaatag cttctttaag tgatatttct
    35161 tgcaaccaat tttcatcagt atctttttta tcttgaacct gatccataac gaatattgca
    35221 tctccattgt cttgatatac tgggtcaaac agagatattg ggtcttgtat ggcatcaagt
    35281 gccattacaa ctgattctac ttctaattct aattcctttg ctatttctga tactgtaggt
    35341 tctttagaat ttgttctaat taatctttct ctaacttgta gtgccttata tgctatatct
    35401 tttaatgacc tacttactct aattgggtta ttgtctctta gataccttct aatttctcct
    35461 ataatcatag gaacagcata agttgaaaac cttacatttt ggcttaaatc aaagttatct
    35521 atagctttta taagaccaat acaacctatt tgaaataaat cgtctatatt ttctcctctg
    35581 ttgttaaact tttttattac actcaagact aatcttaaat tccctcttac aaactgttgt
    35641 ctggcttctt catcaccatt ttttatttgt aataaaagtt ccttcatttg cttattttta
    35701 agaactggaa gttctgatgt attaacacca catatttcaa ccttattaac ttgcatatat
    35761 tttcagtcct ctctcaaaag tattcatcta ttgaaattat ttacatttcc aattttttta
    35821 tactttttaa gaagaattaa tttagcatta tacaaatttt ttcatttctt tttgcaacct
    35881 tgagattatt ttcttttcaa gtctagatat gtaggactgt gatattccaa gcattccagc
    35941 aacttctttt tgtgtttttt caataccttt atcaataaga ccaaatctta attccataat
    36001 ttgcttttct ctgtcactta atctgtcaag tgccataacc aacaaatctc tatctatttc
    36061 ttcttcaatt attttgtata tttcatcatt ttctgtaccc aatacatcag ataataaaag
    36121 ttcgtttcca tctaaatcta tatttaaagg ttcatcaaat gatacttctg ttttcttttt
    36181 attatttttt cttaagtaca ttaatatttc attttctata catctcgaag cataagttgc
    36241 caattttata tttttattca gtttaaaagt attaactgct tttatcaaac ctatagttcc
    36301 tattgaaatc aaatcttcta catctatacc tgtattttca aattttctcg atatgtagac
    36361 tactaatcta agatttcttt ctattaaaat tgactttaca ctttcatctg tttctagctt
    36421 ttgtaaaagc tccatttctt cttctggttt caatggagga ggaagtatat ttgcccctcc
    36481 catatagtat attccctttg gctttattat ttttaattta atacctaaca tagtaataaa
    36541 gcttattatt ctttctttca atcgtaacat tccttgtccc ccttaaattt tcacctaaaa
    36601 tccaggcaat atatttggat tcattattgc tccatattct ctatcattaa aatttgaaat
    36661 accaagtatt atatttccta tcttttgctc atctacttct atatagtcag cttttaagcc
    36721 tattattatg cttgtcttat tacttccagc atgtttataa ggtattattc taactctacc
    36781 tgaagtttta tcatctaaac ttcctataat ttcttgtgct ttcttcatat ctatatcttc
    36841 ataattaata tttaatagtt tttctggaat aaatccttct aacacactag acttaactat
    36901 tattacatca ctttgactta ttgggtcttt taacaaatta ccactatcta ctaaagcttt
    36961 acagcaaaaa cttttttcta gtaagtttat atttatagtc tttgtaagct ccttaatgta
    37021 cttaagcatt ttcaaatctt tataaatgta ttttaataat tcacaactca cataagtaca
    37081 tgcaattaag aaagatattt ttaagtgact tattcctgta aaataaatta taaaataagt
    37141 gcttccagaa ataaaaatgt ttactagata aaaaactaac gctacatgaa cataatcttt
    37201 tttgctctta cttctaaatg aaattaaagt tattatactc atgattatta ttttaaatgg
    37261 tacagtaaat agtatattca ttgatggata caaataagca acagaatagg cacctcctaa
    37321 actagccccc aataacttat tttttttagg attatatctt ttagtaagaa tagaagtaca
    37381 acttataata atataattta ttactaggtt ttctataaca tagtactcaa tatacaccat
    37441 gtatcccccc ttaaaacctt taaacatatt ataagatagt atgtacaaaa ttttatgtca
    37501 cttttgatgg tcgaatccaa aacaaattct atttaaaaag aacaatgata tatgtcttat
    37561 actttatgtc gtcaaaagat atttttttaa tgccaaacaa atagactttt ttgtagaatc
    37621 caatatatct aggtagaagt tattcgctct acttttggta tatttacaaa aaaagactac
    37681 ataatttaat aatatatcaa gtaaatcttt tacttatata aaatcaaatt atatagtctg
    37741 taaattcaaa tataaattat tgtgctagta atccatttgc atattttgca gattcattta
    37801 gtgcttgttc tggagttatg tctccagcta tcatcatttg aagttgtttc cataaatatt
    37861 catatatctc tactccatga ggtccaactg tcaatggtct atacatatgt ttatctcttg
    37921 tcaccatttc ttcaaatctt gggtctcctt ggtatttttc acctttagca actggagctc
    37981 taggtatttc tttgtggaaa gcttccattg attctttgct tagcatatac tcaagaagtt
    38041 taaatccaag ttctttattt ttacatgctg acattaatgt taaatcatct actgaagcaa
    38101 aacttccaac tgtcttatct tctaatgatg ttacatatcc ccagtttaaa tccgggaatg
    38161 atttatcaaa tgtacttgta gcagcagagg atagcattat agtaaatgca gcttttcctg
    38221 gtccaaatac actttcaatc atttcattac tatcttttga taaagcatct tctggaatat
    38281 actttttcat atcatttata aagtttgcag ctttcaagcc ttctgcatta ttaaatttaa
    38341 ctgattttaa atcatcatta tatatatctc caccagcttg ccataaatac ggataccagt
    38401 tccagtttaa gcttccaaat actttagaac cccaaccttg tgcaagaccc cactggtcga
    38461 tttttccatc tccatcagta tcttttgttg ctttttcaca gattctttta aaatcatccc
    38521 atgtttttgg aggtttttct cctaattttt ctagtatatc tttattgtag tacaatacgc
    38581 ctggattagc agcttctata ggtaaaccat aaataccacc catcattttt gcatcatcta
    38641 agtatagata attatctgaa gttcctgatt tttctaaata aggtgttaaa tcttctaccg
    38701 cacccatttc tataaattga ggaaacatct ctgcatacat gtatcctata tctggacctt
    38761 cacctgcact tattgctgtt gcatattttt ctgcgtagtt atcccatggt actatctgaa
    38821 attcaatttc acagttattt tctttttcaa atttttcaaa tatcggcttc catgcatctg
    38881 catcatggtc tgttaatggt gcagaccata caactaattt ttctttaccc tctttgcctt
    38941 tagaatcttc tttttttgaa catcctgcaa gaattgatac tgatagaatc cctaccataa
    39001 ctaaagaaag aacctttttt agtttaatca tgcttaatcc cctttcagac tttaatttgt
    39061 ctttttcctc aaatgtttac atttaattca gatttaatat taacaaataa gattactctt
    39121 gtctaatcat aaaaaactat actaactcct ataactatat tttttttcta tacctattag
    39181 atttaattca tactaaaaac ttacttttta aattttatca atatttaaaa atatttttaa
    39241 gtctagccac aaactaacta tctaaattga acaaaataaa aagaagtcta ttgacttctt
    39301 tataagctta catattatct tcttcttctt aggaatgtag gtatctccat gctctcatca
    39361 tcatcttctt caattatact tgccttttta ggaggctcta ttttttcctc agcaattact
    39421 tcttcttcaa tttcttttac agcttgtttt actgttgtat ttaatgaaga acgtatgctt
    39481 gatttaggtt tagtatctaa atctaaggca ccattttgta atccttcaaa tcctgtcgcg
    39541 attactgtaa tcattatttc atcacctaaa tcttctttta tagaagctcc aaatataaca
    39601 tttgcttctg ggtcacagga ttccataact aaagttgatg cctcattaac ttcaaataat
    39661 cctaagttag gaccacctgt aacattaaga agtactcctt tagctccttg tattgatgtt
    39721 tctagaagtg gagattgaat agcttgtctt gcagcatcaa ttgctctagt ttcaccacta
    39781 gcactaccta tacccatatg agcaagtccc ttgtctttca ttatagtagt aacatctgca
    39841 aagtccaagt ttattaaccc ttcaactgct ataaggtctg aaattgattg tataccttgt
    39901 tttaatacat catctgcaac tgcaaaagca tctaacattg atgtattttt ttgtactatc
    39961 tgtaaaagtc tatcatttgg tatcgttata agagtatcta cttttgattt aagttctgct
    40021 attccacctt cagcgttctt cattcttatc ttaccttcaa atgcaaaagg tttggtaact
    40081 acacctactg taagtatccc catttctttt gccaagcctg caaccactgg agcagctcct
    40141 gtaccagtac caccgcccat tccggctgtt acaaagacca tatcagctcc ttgaagtaac
    40201 tttactattt catctttact ctcctcagca gctcttttcc ctacctctgg atttgctcct
    40261 gctccaagtc ctctagttaa tttttctcct atttgaactt tatattcagc ttttgatgta
    40321 tataaagctt gtttatctgt atttactgat ataaattcaa cgccttttag ttgagcttct
    40381 accattctat tgacagcatt gtttccaccg ccacctacac ctattacttt aatttgtgca
    40441 cattcttcta attctacgtc aaagtttagc atcataaacc cccttctctc atgattcaaa
    40501 gttatcgtat gtattaatta tatcattttc ttcttttatt ttgttaacct ttaagtaaca
    40561 tattccacaa aaacgtaaat tttccttttt aaatttctta cttatattgt caaatattac
    40621 tctttaagta taaaataatt tacgtatata ttaaatgctc tttaattttt acgttttttg
    40681 ttcataatat tactaataat atatcgtcta attatagata agttattaaa caatctcata
    40741 ccaaaaacta atacagcaac atagtaaaga gaaactccta acttttctcc tatataagtc
    40801 aataatatag ccaatatagc attacctatg aaaccagtaa taaaaattac attatcatag
    40861 ttatcttcaa aattggattt tatcgctcca aaaatagaat ccattattgc aagaatagct
    40921 actgacatat atatggaata atccatagaa tatgtaaatg gaatatagta acctactact
    40981 acaccaaatg ctaatcctcc taaaacccat aacataaatc ttcacctctt tattttactt
    41041 tgaaacacaa ctacattaca atccttttta ttaatttttt ttactttttc tttatttttt
    41101 tgtatttttc gttttatttt gcaaataaat tcactttatt tccattattt tcctgaactt
    41161 ttatattaat tccatatata tccttaagag atttagcata tgattctgga gagtttatag
    41221 ctgcactcaa taaatctata tctcctatag cttttattat aaatggttgt ccatatgtag
    41281 tatcatttac tgtaatagtg gctcctgaac attttatctt acttgttgct agtactcttt
    41341 ctccatttat agaaattgct cttgctccag ccttttttaa atcatttaaa accctcaaaa
    41401 tatctatatc atgtataatc aaatcgtttg gattctgtcc gtcttttaac tctctctcac
    41461 tatccctcat agtaatagtt atgcctggcc ctgtaacagt tgaataacca cttaattctt
    41521 taacttcttc aagctctttt tgcataagtg tttggataga ttcatttcca ttcttttttg
    41581 cttctttata ttcattcaaa gtttttttgt tgtttttaag agtttctttt aaatttttta
    41641 tttctttttt tgtattttct acctcacttt caatactttc agtttgacct aatgttatgt
    41701 atactctatt tgggtctagt gattttatat aagttgatat gaaaacgcct aatatgaatg
    41761 ctcctaatat aactattttc tttttcatac tattatttcc cctctgcttt gtttatatca
    41821 ctatgaccat ttatttctat attgtcttct ttggtcactt ttactttggc attataatat
    41881 gtttctattt cccagacaat accatacttt atattaagtg ccgaagccaa tgtatcagaa
    41941 tcaccaattg cttttattat aattggttct tttatgacag tgtcattcat ataaagcttg
    42001 tcttctttta aatacatata tgtattagaa actattctct ggtcgtttat agatatggca
    42061 cttgcttgtg ctgaatttaa tttatttatc attgataata ataaatcata attatatagt
    42121 atactatcat ttttatcaga gtttcctaag tcttttgtag aatttatctc aatttttatg
    42181 cctgttcctt caacatctgt atatccagct aatgtttcat atttttctat ttctgactta
    42241 agtatgtctt gttctccttc attgtttttg cctctataag tctctatatc tttcttcaca
    42301 ctattaactt ctgattgtag attctctttt tcttttttta aagatttaag ttcttctgta
    42361 agttgctctc ctcttttaaa agttgtcatc cctctatttt ctatattaat aattttaagt
    42421 tgtaaactaa caagaacacc caatacaata cttcctatga ttatactttt atttataaat
    42481 ctttttttca atatatcact tccttacaat tgtctatcct tctggactat acactgccaa
    42541 ctttccataa ttaagattta tagtccctcc attagtattt ttattttgca ggtcaatcag
    42601 aattttactt accctagata tattataatc taagttatca tcattagaaa gtaagatttt
    42661 tatattactt cttgtaagca tttctatatt gctttctttt tttaagttta cataatttat
    42721 ttttctataa attccttctt cttttaaata atttaaagtt ttaaatacat tctccttagt
    42781 tttataattt ttaaatttta tagatttatt atcatcaatg ctataatcta catctactat
    42841 caagtctttt ttactttcat tagaacctct tagttcttcc aataaatttc cttttttatc
    42901 tatataacaa taattatctt catcttttaa tactgcaaat atttcttttt cttttaaact
    42961 tataattatc ttattgggaa gttttctttt tatttccaca ttttctatat atggattttt
    43021 tataagttta tttttcatat ctttaaaatt gtatgcaaaa atattttcat ttagatttac
    43081 atttagttct ttcattatat ttgatttggt caccctctta tttccaatta catctatttt
    43141 ctttacatca aataaatcac tttttacaat tatacatata caaaaagata acataagtat
    43201 aaaaactaaa actatcatga cattattcgt atttaacttt cttctttttt tcaaatataa
    43261 tcaacccctt tggttaataa atacaccttt agagcttgtt tttcctacaa aaaaattata
    43321 atatttaaag tcaaattttt gcattttatt acataacatc caaataaggt attaaatttt
    43381 ataaataaat caatatttca tcaaaataaa catagcatac tacatactat ttatatattt
    43441 aaatctgtat acatacaaat aaacccctaa tttataataa tttagaaaat ctaatatatt
    43501 ataaattagg ggtaaatatt tacttatctt ttctttattc ctattacctt agcttgacct
    43561 tctatacttg gagtcgtttc tttttttatt tcttttactt ccttaataac tttttctttt
    43621 tttgtttttt tagaagttga cttttgtgtt gaattgtata ctttcattat ctcatcatat
    43681 ataaggtcta tggcttcagg cttacctata gttttacttg catttgccat atcaaccaaa
    43741 agttctctat ctcctaaaag tttaaatact gctgtattta ggctctctgg agttagattt
    43801 ttttctaaaa tagcaattcc tgccccttgt ttttctatac tcttggcatt atactcttga
    43861 tgattttcag cagtataagc tttaggtatt attatagatg gctttccaag agccgttatc
    43921 tcagctaatg aaattgctcc tgcgctacct ataaccaaat cacttgctgc aagtgcattt
    43981 gccatatctt ctaagtaagg cacaactttt tggtatggtt taagatttat atcgctaata
    44041 cttcccataa attcatcata atagcttttg cctgtagcaa atataaaagc tatatcttca
    44101 tttaccatat tctttattac aagtctcatt gcatcattta tttttcttga acctccacta
    44161 ccaccatagc aaagtaccat tcttttttcg tcacttattg atagattctt tcttgcaata
    44221 ttttttcttg ataataaaat ttcttttcta actggatttc ctgtaaaaac taatttatct
    44281 tctgctgcct ctggaaatct tttatgcgaa tcttcaaaac ttgtaagtac ctttgtaact
    44341 gttttagata aaatcttatt agttacacca ggaaaagaat tttgctcatg tattatggct
    44401 ggtattttcc ccatagatgc attaaataaa acaggtccac taacatatcc accagttcct
    44461 ataactatat ctggtttaaa tttcttaaca atctttcttg attgctccaa acctttaaaa
    44521 agcttaaaaa ctctttttac attatcgaaa tctatttttc gcttaaaacc ttgaactgtt
    44581 acagtcttta attcaaatcc atacttagga actatttctg actctattcc cttttccgtc
    44641 ccaacaaaaa ttatctcagc gtctggatgc tcatctctta ttttgtttgc aatagctata
    44701 gctggataca cgtgccctcc agttccaccg cctgataata aaactttcat caaatcatca
    44761 tctcctgtta attaattttg acatgctttg agatgtttaa cactattcct acagctccca
    44821 taaagatggt gagtgaagtt cctccataac ttataaatgg tagtgctaca cctgtagctg
    44881 gcattgatga tgtcgcaact gctatattta aagctgcttg tattccaatt tgtgcaccta
    44941 tacctataac aaccatacaa gcaaatacat tagaagtctt caaagctatt cttacacatc
    45001 tgtagactaa aactacaaat agcataataa ctattataca accaatcaat cctaactctt
    45061 ctcctattat agcaaatata aagtcatttt gtggctctgg tatataaaaa tacttttgtt
    45121 tactctttcc taagcctaga ccaaacaatc cacctgaacc tagtgcatat agaccttgta
    45181 ttacctgata ccccttacca agagggtctt gaaaagggtc taaaaatgat gtaacacgac
    45241 taagtctata gggttcagca attactaatg cagcaaataa agcagcccca ctccctatca
    45301 tagcaaatac aattttcata tccattccag caacaaatat cattacaaaa gtaactagaa
    45361 ttacagtacc tgctgttgac aaatttggct gaagtattat caacgcaaaa aatatccctg
    45421 gaactacgag aagtggtaca acaccttttg tcaaagattt tattttatca taattttttt
    45481 caattaattt tgcagttaat attattgtag caaactttgc gatttctgca ggttgaaatg
    45541 ttaaagctcc tattcccaac catctttttg ctccgtttgc ttctatccct aaaggggtca
    45601 aaactaacaa taataatact actgctatag ctccaattgc tgtagcattt ttcttccaaa
    45661 aactataatc tattcttgat gtaataatca taactataaa tccaagtaca gcatatatta
    45721 cattcttttt tagaaaatag tacgcatcat tgtgtttaaa tgaagattgt ataaaacttg
    45781 cactaaacac cataactatt cctacaaata ctaaaagcat agtagtgtaa aacactactc
    45841 catcaaattc agtcttcatc cttatgtcaa tttgtttttt caaattttct ttaggcatcc
    45901 aactaatcta cctccattct tccatttaag taagtttaga ggtaagagat tattttaaat
    45961 tgtttacatt atctttgaag tcttttcctc ttacttcaaa actttcatac atatcccaac
    46021 ttgcacaagc tggtgaaaga agcactatat ctccactttt tgaaatttca taagaagtct
    46081 taactgcttc ttccatatct tttactatat gtatgtcatt aaatccttta tttttagcac
    46141 aattttctat atttgatgca gtttctccta ataagaccaa tgatttaaca tatgactttg
    46201 cagtttcaag aagttcatca aaattacttc ccttatccat cccccctgct atgagtatta
    46261 taggtctatc ataagactgt atagctttta tagtggaatc tggattagtt ccctttgaat
    46321 catttacata tattacattg tctaaatttc ttacaaactc ttgtctgtgt tccactcctt
    46381 taaatgtcat aagtacgtcc tttataactt ctaaatcaat tttgcagaca tatgctattg
    46441 ctatagctgc catacaattt tctaagttat gacctccagg taaacttaca tcatctttat
    46501 ttagaaattt gattttatca tctatatcta ttattatgtc attattttct aaatatactc
    46561 ctccatttac ttttttagtt cttgaaaagt aaattacttt ggcattgcat ttatcagcta
    46621 aagattttac tatctcatca tcatagttca atacacagaa atcctcaaca gtttggttca
    46681 taaatatatt tgcctttgct tttatgtatt tttccatagt atggtgtcta tttaaatggt
    46741 cctctgtaat atttaatatt gcgcttactt taggtctaaa ttcatctata ctctcaagct
    46801 gaaaactgct tagttcagtt actaacacag actcttcact tgaagtttct atagtatcta
    46861 ttacaggatt tcctatatta ccaactacat atgtatctcg ttttgctctt gaaaaaattt
    46921 ctcctaccaa actagttgta gttgtctttc catttgtacc tgtaatccct ataaaaattg
    46981 gattattcga tagtttaaaa gctaattcta cctcaccaat tatatacttg cctgaatttt
    47041 ttaatttcaa tatgaatggt aggtctagtg gtacacctgg agacactaca accatatcta
    47101 tatcatctac atcttctggg tgatgtccta atatgtattt tatgtcattt atagatttca
    47161 attcatcaag tatatttctc aatttatttt catcttttat atcatttacg attatacttg
    47221 cacccaattt atctaaatgt ttaattgtag atataccagt ttttgcaagt cctactaata
    47281 aaactttttt tccttttaag tccatttttc attcccccta gccctaaaat actgctatta
    47341 tacttatcca agctaaaaca actgttataa tccaaaaaat aaatacaact cttgtttctg
    47401 gccaaccaca ctgttcaaag tggtggtgta ttggagccat cttaaagaat ctctttcttg
    47461 ttgccttaaa atatccaact tgaatcaaaa ctgatagagc ctccgcaaaa taaattcctc
    47521 caattatagg tattataagc actgagttag ttagaactga aaatgctaca actgcacctc
    47581 ctaatgccat tgaacctgtg tcgcccataa acactctagc cggatatgaa ttaaatccta
    47641 agaaacctaa acatgctcca acagttgctg ctgctaaaac tgcgacttct gtatttccag
    47701 caatagaact tgcaaatagc ataaagaata cagaaactat taatgttact cctgatgcta
    47761 atccatctaa tccatcagtc aagtttacag catttactat tgctacgatt ataaacatca
    47821 ttattggtat atataatatt ccaacattta tcacaaaatc tgtaaatggt atcataagtt
    47881 gtgaagcact tgatgatgat gtatactgat aaaaagcaac ataaaaagat aatgcaactt
    47941 gaaggattat tttttgatat gcttttagtc caagtgatct ttttagcttt atttttataa
    48001 aatcatctaa aaagccaata aaaccaaaac ctgcaataca tataagacct actgccatat
    48061 catgactaac ttttactctt gtaagtccag ttattagaat tgcaacaatc attataattc
    48121 cacccatagt aggtgttccg tttttagcta gatgtgtttg gggtccatca tctctaactg
    48181 tctgaccaaa tttaaatttt ctaagcattg gtataaatat tggtcctatt ataattacta
    48241 ttaaaaacgc aatcaatgcg gtgtacgtaa gctctgttat tcctaacatc ataaaactcc
    48301 tctcccttgt caattaactc attagtttaa gcttatttat ttagatattc gactattttt
    48361 tctaatctca tgcctcttga gccttttact aaaatagtgt ctcctgtttt tactaattca
    48421 tttaacttgt taaacacatc ttctctattc tcaaagtgat atatattggc tgaattgaat
    48481 cctaattgtt ttgcttcttc tccaataaac actgaatttt cacctatagt tattataata
    48541 tcagtattat tcatagatga ttttccaact aatctatgac catactctga aatttcaccc
    48601 atttctagta tatctccaag tatcgctacc cttctacctt tatatcttcc aagtatcttt
    48661 aaagcagcat ccatagaatc tggactagca ttatatgaat cattaattat tgttaatttt
    48721 tcatttttta ttatgtctaa tctcattttt gtccctttaa aattttttaa accttttttt
    48781 atataatcta aagaaatatt tagacacaaa ccaactaata tagcagacat tgcattatat
    48841 atattatgtt ctcctattgt tggtataaat atttcctctt ttttcccatt tattacacat
    48901 ataaatgtta aactatcctc ttccatagta taactttcac aataaacatc attgttttta
    48961 ttaaagccaa atgtttttaa cttatataca tgttcttttt cttttaatgt agataaaaac
    49021 ttatcatctc catttacaat taaagtattt gtttcatcaa agtttgaagt aatctccatc
    49081 tttgctttca aaataccctc ttgtgaacct agtttttcta catgtgataa tcctatattc
    49141 gatatgactg caattttagg atttactata tccactaaat attttatttc attgaatcca
    49201 gacataccca tctctattac agcacactca tgttctttat ttagattaaa taaagtcaat
    49261 ggaactccaa aatgattatt taagtttttt tcatttttta gtatatttaa ctttgcagat
    49321 atggcagagt aaatcatatc tctagtagta gtttttccca cactacctgt aacacctata
    49381 aatggaatat caaatttttc tttatagtat tttgaaatat ctcctagagc caaagatgta
    49441 tcttttacct ctattaaatt tatatccgaa ctttctaatt ttattccatt actttcattt
    49501 tttataaaag ttttacatcc actatcatat gcagacttca taaatgtatg cccatctaaa
    49561 ttttctccaa ctatggctac aaatgcattt tgggcatttg cctccctgct atctataact
    49621 atatcactta cacagtcatt ataatctcca tatattaact tcccattagt tgcaagtact
    49681 aactctttta ttgttaagca ctccattatt aaactcctcc tttaaaacct tagctatatt
    49741 ctcttagcaa caaaaggcaa tgtataccgt tatatataca ttgcctacga taactcttaa
    49801 ctttataatt atatactata tttctgtttt tttgaagatg tttatgggta tatgttaatt
    49861 atctgttact ttttagtttt caaaatatag ggttatactt gagtcttcat taacttttac
    49921 tccaggtttt gggaatatat cctttacctt tgtatcttct ggaagttcta tatctgcatc
    49981 taagtctggt tttaacttcg catcctccaa tgcctttaca gcatctccta tttttagatt
    50041 tcttacatct ggcactttaa cttgcttctt ttcatactca gctttctctt cttctttata
    50101 tactggttta actcccaaat attttaaaga gtcattcatt atttctttca ctattggtcc
    50161 tgctgtagta ctaccaaatg cacttactcc tgttggttcg tcaacaatag caagaactac
    50221 tatttgcggg tcatcacaag gtgctattcc aacaaatgaa catatatatt ttcctggagc
    50281 atacttacca tctataactt tttgagctgt acctgtttta ccaccaagtc tataacctgg
    50341 tatatatgct atctttcctc caccttcagt tacaactgat tctgcaattt ctaacatttt
    50401 tttagatgtt tctttagata taacacttct tacttttttt ggttttactg tttcagttat
    50461 atttccttta ttgtcagtat aagattttac cactcttggt tgcattaaat ctccaccatt
    50521 agctattgat gatatagctg ttataagttg tattggagtt actgatatag attgaccaaa
    50581 tgatattgta gccaattcaa ctggtcctac atttttttcg ttatacagta ttcccttagc
    50641 ttctcctggt aaatctatac ctgtcttatc cataagacca aatgattcta tataatcata
    50701 catttttcca acacctaatc tgcttcctaa ctcaacaaat actgggttgc aagagttttg
    50761 tactgcttgt ttaaattctt gtgttccatg aggtctgtaa tgtctccaac atttaatctt
    50821 tcttcctcca acagttacac tacctgtaca tgtgaatttt tctccatctt taattactcc
    50881 ttcttcaaga gcactggaag atgtaataag cttaaatgta gaacctggtt catatgtatc
    50941 acttactgct ggatttctcc acatttgata atagcctttt attttatctt tatcattata
    51001 tttttcaagt tcttcttgat aatatggata tattggcgtt cttgagtcat tagggtcata
    51061 atctggtttt gatgctaaag caagtatatc acctgtttta gggttcatag ctattgcagt
    51121 aacctttttt gcattattta actcataagc tttctgtact gctttttcag tatagtgttg
    51181 aattacttca tctatagaca acacaagacc attaccttgt acaggctcat aatatttttc
    51241 cattccttgt ggtatttctc ttcctgaagc atcagtactt actataagtt ttccaggctt
    51301 tccttttaac tttttatcat attgcatttc tacaccagat atacctgttg catctgaaga
    51361 agtatgtcct aacacatatg gtgcaaaatt cccatatggg taatatcttt gattatcttc
    51421 tgccacccat attccactta atttagcatc tcttatttga cttgccttat catcatctat
    51481 ccatcttttt acttttacaa gagccatatt ttttttgctt attaaagcgt aaatatcttt
    51541 ataatcttca tccaaaatct cagctacctt ttcggctgct tcttttttat cttctacttc
    51601 cacaggttta caccaaacag tatacttagt tacacttact gctaactctt tcatatttct
    51661 atcatatata gttcctcttt tgggttctat tggtatatct cttgtttgtt gttctagtgc
    51721 ttttgtactc aaccaatttc ccttcataag ttgtagatac ccagtcctaa taacaaggca
    51781 aaaaaacaat gcacatgcta gaataagaac gagtaccagc cttttcttac ttatcctctt
    51841 tacttttctc aaatctattc cccctagtta tccacatcta tatactttat ttgtccatct
    51901 tttggatagt ccatattgag caattcctta gcctttagct caatttcttt tatcgatgtt
    51961 ttttcagttt cttttgcctt tagttcctct aatactatct ctttttttct taaatctttt
    52021 tgtaaataat agatatcgta cttcatttcc gagatttttg aataaccaca tagattcaat
    52081 attattactg aaaaagttgc aatcagtaaa atgcatttag ctcctatttt tttcttattt
    52141 ctctttttat aattattctt ttttttattt ttatattcat ttagattatg tattttataa
    52201 ttttttttca aattctcacc ccgatagtat atagtttaaa ttttcctcta tactatattt
    52261 gttattaatc atatttcttc ctctaaaatt tcatcgctaa attaatacac tattacacaa
    52321 tctaattgta tttttttcta tacacaacaa aaacctataa attcacttat acttttatat
    52381 gaatctatag gttagatatt aatttctatt tatttttatc acttctagta tttttagata
    52441 atttcttcca taaatataat atgtaactaa ctatctactc tctgattcct aagttctcca
    52501 ttatattact taataccatc tatatctata tttttatatc taaattttca ttttatatct
    52561 caataacaaa gaacatttct tatagtgtta attgtttttt aattgcttta ccagtgcaac
    52621 aaaatatata atacttttta attaattata ataatcttat atataagatt attctttagc
    52681 cttataacta cttatatttt ttctgctact cttagcttag cacttcttga acgtggattt
    52741 atttctattt cttcctcact aggtaatata ggttttctag ttattatttt cacctcagat
    52801 tctttatcac attggcatat aggtaaatgc tgtggacata tacaatctga tgctaaatgc
    52861 ttaaatgcat ttttcactat tctatcttct aatgaatgga atgttattat acatattctt
    52921 ccaccttcat tcattataga agaagcatca tttatcattt ttgtaattac tccaagttca
    52981 ttatttactt ctattcgtat tgcctgaaaa gttcttttag ctgggtgagg tccatctatt
    53041 ctagctttct tagggatagc ttttttaatt acatctacta attctcctgt agtttctatt
    53101 ggtttgtttg ctctttcttc aactataaat ttagctatac gcttagccca gttatcttct
    53161 ccataatctt ttattatctt agttaattca tcttctgtat aagtatttac aacatcatat
    53221 gcagaaaact cacacctaac atccattctc atatcaagtg gtgcatcttg catataagaa
    53281 aatcctctat cagcttcatc aagttgatga gatgaaactc ctaaatcagc taatacacca
    53341 tcaattttgt aaactcctat tttttctaat tcctctttta tattttcaaa attgctgtga
    53401 acaaacttca ctctactttc atattcactc aatctctctt ttgctgtgct tatagcattt
    53461 ttatcttggt caaaccctat aaataatccc ttatctgata atttttttac tatttcttta
    53521 gaatgtcctg ctcctcccat agtacagtca acatacacgc catctggctt tatatttaaa
    53581 ttctctatac actcatttaa aagaactgat acatgatgaa attccatagt tacctccctt
    53641 aaattcactt tttaaactat tcttcactaa tattattttt atttttcttt gataaataaa
    53701 catgtgcaat tatgccacca ataactccaa ttagacttat aacttgtgcc attctaagtg
    53761 gtcctaacat taaactatct gttcttaatc cctctataaa aaatcttcct attgaatata
    53821 aagttatata agtaactata acttgacctt catatttttt attttttcta aatagtaata
    53881 aaactataaa tattccaaaa tcccatatag actcatataa aaaagttgga tgtaccttta
    53941 ctccatcaac cattattccc caaggtaaat tggtagcacc tccatgtgct tctccattaa
    54001 taaaatttcc ccatcttcca atagcttgtg ctaaaggcat tccaagtata actgtatcag
    54061 ccatttttaa gaagttaata tttttaatct tagtgtatat ataaccagct aatattccac
    54121 caattaaccc tccatgtata gcaaggccac cacctctaaa attaaaaatt tgagacatat
    54181 tttgagcata gtaactccaa ttaaatacaa cataatagat tcttgcacag attagtccaa
    54241 ctggaattgc tattatagct atatttaata catcatcttc tttaattccc actctttttg
    54301 cttcttttat tgctattaaa gttcctaaaa tcattccaca tgccataagt attccatacc
    54361 acatgatgtc tatgccaaac agtgtaaatg ctactctatc cataacgtca cctctttgta
    54421 ttaattgaaa atatttccaa agcaatatgc tataattaca attaattgta attatactaa
    54481 attatgataa cacattaatg ttaattctac aaaaaatatt aaaatttatt ctacaactcc
    54541 ctacactata ttatatctaa ttactataaa attttttaaa ctgaatctct catgactaaa
    54601 gttacaagtg tacatagata ttttttaatc aaaaagattg atgcatatat acatcaacct
    54661 tttctatttc ttatctatag ctcttaaatt tttacctcaa tttatataaa tatattttat
    54721 aaatttgttt taccaaaata aacatttaaa aacataaact aatacttaat tagttattct
    54781 tattatgatt aagtttctat ttaggctcta caatagaaat aacacaatac tcttctttaa
    54841 aatgatcttt taatctttct tcaacttcct caaaagtaat atctttaata atatctaaat
    54901 aatccaatag atttatatcc ttaaaaacat aagatataaa actattacct ataaagttta
    54961 tagaatcaaa gcacttaata aatgacccta tttttttctt tttagttctc tcaaactctt
    55021 cttttgataa tccttctttt tttgattttt ctatataatc aagaattatt tcttttactt
    55081 ttttaggctc tttagaatct ccagctatta tgctaaaagc ataatccact tgagacgaaa
    55141 atccagctcc aaaattttca tttattaaac cttgcatata caaatcttca taaagcttac
    55201 ttcctttttt aaataacatc cctacaagta tatcagttac aatctcttta cgtaaaagtt
    55261 ctttcccttt taaaccaaca ttgctatctt taaaacctat gttgaacata ggcatagata
    55321 tagggaattt ttctataacc tctttttctt ttacactttc tggttcttct ggataaaatc
    55381 tttctatact cttagagagt ttgtctactt tgtaattgtt tgaattttta gttacatcta
    55441 taactttttc tacatctaag tcaccaacaa caaataaagc catatttcct ggattataga
    55501 aagtattata acatttatat agctcttcct tagttatctt atatatacta tcaacagtac
    55561 ctgctatatc aattctagca ggataattta catacattgc cttcaagcaa ttaaagtata
    55621 cattccaatc agggtcatca ttgtacattt ttatctcttg tgctattata cctttttcct
    55681 tttcaacatt ttcatctgta aaataaggtg tttgaacata gtcaattaga tgttctaaac
    55741 tctcataaaa attttcagta gcagaaaata agtaggctgt cattgtaaaa ttagtaaatg
    55801 catttgcatt tactcctaat tttgaaaatt tatcaaatgc atctcctcca tcaggttgct
    55861 caaacatctt atgctctaga aaatgtgcaa taccttcatt cactctaatt ttcttatctt
    55921 ctccaattgg tacaaattct aagtcatttg aaccataatt agtagccaaa atagcatact
    55981 ttttcataaa acccctttta ggcataaaat atacatctaa tccattttgc aatttctcat
    56041 aataaacttc ttctttcaat atatcattaa ctattttttc catagacatc tcctccatta
    56101 atttctcaag aagtatacag tatcaagctc tatatttttt atagcttcaa ctatatcttt
    56161 ttttgtaacc ttttctatac tagatattat atcttgtact tcagaatttg tctttgccat
    56221 agattgagag aaaacaaaat cagacatacc acctatatta tcagttatag atttcataga
    56281 attaactaaa gcaagtttac tgttttctaa ctcttcatca gatatatcac ctacttttac
    56341 actttctact tgttttttta tcaattctac agctttatca taatctttag tttctatacc
    56401 agatgatata aacatgatac ttttatactt ctctattgaa gagaatatat agtaacataa
    56461 actttctttt tctcttacat taacaaataa tttagagtgt ggaccaccac ctaagacatt
    56521 gctcccaact actaaagcat aatatttatc tatgtctgca taatccacat ttgctctata
    56581 acccataact aacttacctt gagttatttc catttgttca tctataactt ttacctcatc
    56641 cacatttttt ataaaatctg ctcttggtat atttataatt tcttctcttt caaattttag
    56701 atttttactt attatatcta caactttatc ttcatcaaaa ttaccttcta caactatatc
    56761 tataggtgat gttttaagta tgtttttata atgttcatat aactctcttg aagttatact
    56821 atctatttca tcttcataac caaattcact tacactatat ctctctcctt tacacatagc
    56881 ctcaatacat ttatcttgcg catattcctt tttatcattt attattgatt gtatcttttc
    56941 tcttaaattc tctttttcaa tatttaaata ttcttcttta aacccaccat ctacaacaag
    57001 cgtattattt attacttcat taaaaaattc tactacttct tcaaatatac tctcatctaa
    57061 atacttttca cttatgttaa ttactttaaa actcaatact tgacgttctc cacgttttac
    57121 agcatcagct cccatagatg aaccatataa atcatctaat ttattggata ttgctctagc
    57181 actaggatat ttagcgcttc cacttgctat tattgatggt attagagcat tttttgtagt
    57241 ttctttttca tccaatagtc tctgaacata taaacttata agattcgatt taaacttttc
    57301 tgtttttatc aaagtaagat taatattatt acctaaattt attatttttt tagtattaac
    57361 catatgtacc tcctattttt atttaaacat caattttaaa attgaaattt atttattttt
    57421 taattacata tactcacata taaaaacctt ctatttaatt atatcctttt tattattttc
    57481 taaaagcaat atttttattt aaattaaata caaatattat ttaaatcaat atgctttaaa
    57541 gtctagttta caagcttgat atatatgatg tataatcaat atgtatgtct ataattaaaa
    57601 caattttgca atcctataga ttgattgttt aaagttatat aaagaatata aaaaagaata
    57661 agagagagga cgattaatat gaaattaggt atagttggtt taccaaatgt aggtaaaagc
    57721 acactattta acgcaataac tcaagcaggt gcagaatctg caaattaccc tttttgtaca
    57781 atagacccaa atgtgggagt tgtatctgtt ccagatgaaa gattaaacaa actacaagaa
    57841 ttatataatt ctgaaaaaat agttcctact gctatagaat tttgtgatat agcaggttta
    57901 gttagaggag cttctaaagg agaaggttta ggaaataaat tcttatcaca tataagagaa
    57961 gttgatgcaa tagttcatgt tgttagatgt tttgaggatg aaaatgttgt acatgtagat
    58021 ggttctgtag acccacttcg tgatatagaa actataaact tagaattaat tttctcagat
    58081 atagagattc ttgaaagaag aattaataaa actcaaaaag ctgctaaggc tgataaaact
    58141 ttaggttctg aacttgattt attaaaatca ataatgtcta ctttagaaga aagtaagtgt
    58201 gtaagaacta tggaatttac agaagatgaa caaacattcg taaattcatt ggatttactt
    58261 acatctaagc ctgtaatata tgcttcaaat gtatcagaag atgatttagc tgataatgga
    58321 gaaaataata aatatgttca acaagttaaa gcatttgcag aaacagaaga tgccgaagtt
    58381 gttgtagtat gtgcacaaat agaagcagaa atttctgaac ttgattctgc tgaagaaaag
    58441 aaagagtttt tagaaacatt aggtcttgaa caatcagggc ttgataagct tataaaatct
    58501 tcttatgctt tacttggttt aatttcattc ttaactgctg gtccaaaaga agttagagca
    58561 tggactataa aagttggaag taaagctcct caggcaggag gaaaaataca ttctgatata
    58621 gaaagaggat ttatcagagc agaaacaata gcctttaatg atttggttga gcatggtact
    58681 atggctgctg ctaaagaaaa aggattggtt aaattagaag gtaaagaata catagttaaa
    58741 gatggagatg taatattatt tagatttaat gtttaaaatg attaatcgta tacactttga
    58801 ctattatata taataactaa aaaa
//
LOCUS       DAEPXW010000010        57278 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.010, whole genome shotgun sequence.
ACCESSION   DAEPXW010000010 DAEPXW010000000
VERSION     DAEPXW010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57278
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.010"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(154..2034)
                     /locus_tag="KRM55_000629"
     CDS             complement(154..2034)
                     /locus_tag="KRM55_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBH1592900.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPNNGNGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGTDRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNDKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(2244..8207)
                     /locus_tag="KRM55_000630"
     CDS             complement(2244..8207)
                     /locus_tag="KRM55_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HBH1592901.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMDDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDEQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDNNSTTSTYSRSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKILTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKIDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPEAEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIDTMNNADQTRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKSNIVRDK"
     regulatory      complement(8331..8416)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(8588..9991)
                     /locus_tag="KRM55_000631"
     CDS             complement(8588..9991)
                     /locus_tag="KRM55_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBH1592902.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILVNSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(10453..12348)
                     /locus_tag="KRM55_000632"
     CDS             complement(10453..12348)
                     /locus_tag="KRM55_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBH1592903.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKGGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            complement(12975..13118)
                     /gene="scfA"
                     /locus_tag="KRM55_000633"
     CDS             complement(12975..13118)
                     /gene="scfA"
                     /locus_tag="KRM55_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBH1592904.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(13184..13546)
                     /locus_tag="KRM55_000634"
     CDS             complement(13184..13546)
                     /locus_tag="KRM55_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBH1592905.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEIGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(13604..13897)
                     /gene="yajC"
                     /locus_tag="KRM55_000635"
     CDS             complement(13604..13897)
                     /gene="yajC"
                     /locus_tag="KRM55_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBH1592906.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(14031..15152)
                     /gene="tgt"
                     /locus_tag="KRM55_000636"
     CDS             complement(14031..15152)
                     /gene="tgt"
                     /locus_tag="KRM55_000636"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBH1592907.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(15231..15716)
                     /locus_tag="KRM55_000637"
     CDS             complement(15231..15716)
                     /locus_tag="KRM55_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592908.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(15728..16753)
                     /gene="queA"
                     /locus_tag="KRM55_000638"
     CDS             complement(15728..16753)
                     /gene="queA"
                     /locus_tag="KRM55_000638"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBH1592909.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEFLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(17071..18090)
                     /gene="ruvB"
                     /locus_tag="KRM55_000639"
     CDS             complement(17071..18090)
                     /gene="ruvB"
                     /locus_tag="KRM55_000639"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBH1592910.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(18197..18799)
                     /gene="ruvA"
                     /locus_tag="KRM55_000640"
     CDS             complement(18197..18799)
                     /gene="ruvA"
                     /locus_tag="KRM55_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBH1592911.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(18792..19301)
                     /gene="ruvC"
                     /locus_tag="KRM55_000641"
     CDS             complement(18792..19301)
                     /gene="ruvC"
                     /locus_tag="KRM55_000641"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBH1592912.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(19613..20242)
                     /locus_tag="KRM55_000642"
     CDS             complement(19613..20242)
                     /locus_tag="KRM55_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592913.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            20445..20768
                     /locus_tag="KRM55_000643"
     CDS             20445..20768
                     /locus_tag="KRM55_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH1592914.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            21036..21890
                     /locus_tag="KRM55_000644"
     CDS             21036..21890
                     /locus_tag="KRM55_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592915.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIESKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(22076..23512)
                     /locus_tag="KRM55_000645"
     CDS             complement(22076..23512)
                     /locus_tag="KRM55_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBH1592916.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTKGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKILGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIISMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(23583..24965)
                     /locus_tag="KRM55_000646"
     CDS             complement(23583..24965)
                     /locus_tag="KRM55_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1592917.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(25101..26006)
                     /gene="garR"
                     /locus_tag="KRM55_000647"
     CDS             complement(25101..26006)
                     /gene="garR"
                     /locus_tag="KRM55_000647"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBH1592918.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHDN"
     gene            26401..27072
                     /locus_tag="KRM55_000648"
     CDS             26401..27072
                     /locus_tag="KRM55_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1592919.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            27175..27723
                     /locus_tag="KRM55_000649"
     CDS             27175..27723
                     /locus_tag="KRM55_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592920.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            27981..28289
                     /locus_tag="KRM55_000650"
     CDS             27981..28289
                     /locus_tag="KRM55_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592921.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(28451..30241)
                     /locus_tag="KRM55_000651"
     CDS             complement(28451..30241)
                     /locus_tag="KRM55_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1592922.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(30241..31968)
                     /locus_tag="KRM55_000652"
     CDS             complement(30241..31968)
                     /locus_tag="KRM55_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1592923.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(32213..32479)
                     /locus_tag="KRM55_000653"
     CDS             complement(32213..32479)
                     /locus_tag="KRM55_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HBH1592924.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            32777..33889
                     /locus_tag="KRM55_000654"
     CDS             32777..33889
                     /locus_tag="KRM55_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH1592925.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKSYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(34254..34763)
                     /locus_tag="KRM55_000655"
     CDS             complement(34254..34763)
                     /locus_tag="KRM55_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH1592926.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(34765..35412)
                     /locus_tag="KRM55_000656"
     CDS             complement(34765..35412)
                     /locus_tag="KRM55_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592927.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(35426..36598)
                     /locus_tag="KRM55_000657"
     CDS             complement(35426..36598)
                     /locus_tag="KRM55_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1592928.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAE
                     RLKLEFEKEGLDCELVDVGDNGSTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            36866..38242
                     /locus_tag="KRM55_000658"
     CDS             36866..38242
                     /locus_tag="KRM55_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592929.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(38492..38851)
                     /locus_tag="KRM55_000659"
                     /pseudo
     CDS             complement(38492..38851)
                     /locus_tag="KRM55_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(39178..39708)
                     /locus_tag="KRM55_000660"
     CDS             complement(39178..39708)
                     /locus_tag="KRM55_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1592930.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(39796..40890)
                     /locus_tag="KRM55_000661"
     CDS             complement(39796..40890)
                     /locus_tag="KRM55_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBH1592931.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVIKYKKIVDEIHNSGAKVSAQLFCSDYDAN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            complement(40892..41338)
                     /locus_tag="KRM55_000662"
     CDS             complement(40892..41338)
                     /locus_tag="KRM55_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1592932.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            41644..42834
                     /locus_tag="KRM55_000663"
     CDS             41644..42834
                     /locus_tag="KRM55_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1592933.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKSLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            43004..43966
                     /locus_tag="KRM55_000664"
     CDS             43004..43966
                     /locus_tag="KRM55_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH1592934.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(44088..44750)
                     /gene="zmp1"
                     /locus_tag="KRM55_000665"
     CDS             complement(44088..44750)
                     /gene="zmp1"
                     /locus_tag="KRM55_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBH1592935.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(44850..44935)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(45121..48039)
                     /locus_tag="KRM55_000666"
                     /pseudo
     CDS             complement(45121..48039)
                     /locus_tag="KRM55_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
     regulatory      complement(48157..48242)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(48369..49547)
                     /locus_tag="KRM55_000667"
     CDS             complement(48369..49547)
                     /locus_tag="KRM55_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1592936.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDVVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     gene            49922..50107
                     /locus_tag="KRM55_000668"
     CDS             49922..50107
                     /locus_tag="KRM55_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH1592937.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            complement(50172..52946)
                     /locus_tag="KRM55_000669"
     CDS             complement(50172..52946)
                     /locus_tag="KRM55_000669"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH1592938.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(53118..54374)
                     /locus_tag="KRM55_000670"
     CDS             complement(53118..54374)
                     /locus_tag="KRM55_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH1592939.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRNKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(54446..55948)
                     /locus_tag="KRM55_000671"
     CDS             complement(54446..55948)
                     /locus_tag="KRM55_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH1592940.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTSAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            complement(56039..57228)
                     /locus_tag="KRM55_000672"
                     /pseudo
     CDS             complement(56039..57228)
                     /locus_tag="KRM55_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
BASE COUNT        18153 a         9958 c         6661 g        22506 t
ORIGIN      
        1 ctttatttaa aattaaactt aatatagctc aaattattat acattttaac ctcaatatta
       61 ttagattgtt aagataatga aaataaaata agaatgcatt taaatatata actttatatc
      121 taaatacatt cttattttct atttacttaa tatttatttt tcaattaaac tcttaatctt
      181 gtctattaca gatgaggcta ttcctccacc tacttcaaac aactttgatg aatttttacc
      241 ttttaatgac gattcttgtg atttatctaa cgtatttgta gcaagtataa ctggtgaatt
      301 gtttttagct gctaatggtc caactgctaa agcgtctata agtttgtctt gatttgcaac
      361 tacaactcca tctagcttag attgagagta gaatttatct attactttgg cattcgtctc
      421 ttgtctagtt tgacctgcca ccctattgtt tgatatatct ttgtttgcta tttttccaac
      481 ttgttcaata gccttgttag atattttttc tactccacca ataaaatata tatttgacac
      541 cttatttgat ttaataaatt gttcagcttc attatctaca ccatcttttt gtgtaagtac
      601 tattggagtt ttttctttac cagccagtga tgctattgat aatgaatcag cttctccatt
      661 tcctgctcct atatacaact tgcttacatt attcgtctta tctatttctt ttgctatatt
      721 aatagaagtt tgatatcttg tatctccacc tattctttgt actgatattt ttgaatttac
      781 agctttgata gcttcaacaa ctgaatttgg cattgagttg tttccaccta tcacaattac
      841 ttttgatgga tttagccttt tcaattcttc tacagttttt tgaggaagtt tatcatttga
      901 tgataaaaga atcggtgagt tttttacact agcaagtggt gtagctgtaa gcccatccac
      961 catactttta tcttctccat ttactattac aactgtatct gattttgtcc aaccactttg
     1021 agatattttg atagctgtct caaatctatc agtacctttt aattttttga ctgtgacatt
     1081 agatgtagaa tcacttgaat ttcctcctcc agagcttcca ccactagatg agccgcctga
     1141 attacttcct ccaccattat ttccaccatt gccattattt ggtggtaatt catccggttt
     1201 ggataattca ttttcaacta tgtattctaa actttttgga agtgtaactt caacatattt
     1261 gtttattgta gcttttcttc ccttagttgt tttttgtgct aatccaagtt ttaatattac
     1321 atttgaacca ctttcttgtg tttctttact aacaatagaa tagtttatcc taatattgtt
     1381 taataaatat tcaagtgctt cacttttctc taccttatac ttttcagggt cgtttttact
     1441 agaaccagtt ccaccaatcg gttttacttc actctcatta ataagggtaa atattaatcc
     1501 ttcatcagag cttatatttt cataatccac tgttttgttg ttatatgtta caatttttaa
     1561 agctggttta tcgtttgttc cttttcctaa aactttatag tcagcatttg agttactgcc
     1621 agattttttt acagatattc ttcctatatt caatctattt ccgtctagta agtcttcatt
     1681 tgatgtaacg tatatatcta atgtagttgt attacttgat ttgttgtatt ctgctctaca
     1741 agtagcattt gcatttccac tttttatctg agattttata ttatcagacc aagtaatctt
     1801 ttctttctgc tcattatcta ctacttcaac ctcaccttgt acttttatac tggcttgaaa
     1861 tgaatatact atgttttcta ctgagtccac agatatatct atagtattta ctttctcata
     1921 cgtttttgtt ccttgtaaaa ctggagctgc atatgcacat gtagcactac cagttacagc
     1981 tactgccata gttgatactg ctatagttct tataaaagat tttcttttac tcattaacac
     2041 ccgtccttat ctatcattaa ctaagtggat aaatttactt atccacctag cttttatatt
     2101 taatttataa attaccctaa acttatagtt acatttatat actttacttt taatatctac
     2161 tattttaaaa ctattctagt acctaatcat attagatata caatgttagt gttagtattt
     2221 tcacgttttt agagttccac ctactattta tctctaacaa tattactctt tactttattg
     2281 cttacagtta taaccttctt attactgata tcaatagaat ttcttgtagc ttttctagct
     2341 ttactattac tatcagtaag acttattgtc tttaactcat cataattctt agctcctaca
     2401 ggtacataca ttgtatcact tacaaatctt tgacctactg gagtatctcc ttgaaggtca
     2461 ttgtatctat atagttcagc cttaacctta tcacttaaag aatcaaagtt ttcttttggc
     2521 atatagtaaa cccatgtacc tttactgatt tcacctagtt cacctttttc tggaacttct
     2581 gcaaataaaa gtgcttctcc agatatagtc ttattgtttt tatctataag tagtggtaaa
     2641 ttaaatgctg gatttccact gtattcacct gtaataacta ttgaacccgc tggaatctta
     2701 cctgtttcat cttcacttgt gctagagtca tcactttgat atacataatc ttctgctaat
     2761 tttccaattc cattagtacg agtttggtct gcattattca ttgtgtcaat ttctatatta
     2821 tcacctggag gtcctattat atctaattct gcaacttcta tattagactt attatttgag
     2881 attagtttta catatctagc ttggtatgtc caaagtttac catctttatt aaatgtaact
     2941 ctagcttcat tatcttggtc ttttcctcca ccaactaaat cttgtccata ttcaaaagtt
     3001 ccttgactta catcttccca gttcttttta tcattactta cttgtatctt gtaattagtt
     3061 aaaggattgt atgttgtact agtattcttt ctaaagttaa ataatccttt taatgagaac
     3121 ttcctagctt ctgcctctgg ttttgtatat tttagtccta ctataggtaa tgtttctttc
     3181 atgtctacta ttatatatgg attttcttct acatttatat cagggtcttt ttgagggtct
     3241 ttgttccact ctgctttact tattatcttt cctttatatg tagtacttgc atcattatct
     3301 tttatattat caatttcagg attttgtaat ggtccatgtg agtcattttc agttctaaca
     3361 tcaccgtcag aaacagtatt tgttatgaat gaccatgctg atttatttat tttcccttca
     3421 tctgataatt ttacagtacc aacttcaaat tcttctgttg gatttaggtg ataatcatat
     3481 gcaactacct tatatgtaaa tgctctgtta ttaagaggag atatattatc agtaaattta
     3541 gtcttactat ttccttttgc atccacaaat ccaactgttc tgtattttac ctgtgttcca
     3601 ttttcaccat ctaaataatt tccatcactt cttattattt cgtatcctag tatcttatct
     3661 ttatccttat ctacatctag gtctatagat attttattag atttaactag agaaccactt
     3721 tgtattccat cagaaaaact agcacttact ttagtatctt ttgccatact agctatattt
     3781 tcatttaaaa tctttcttct agcttcgtca tttacatatt gtatctttct tgattctttt
     3841 tcgtagttct tactatccat tatactgttt aattctggtg taatttctac tccccatgcc
     3901 ttaaagtaat ctcttaaatc tttttcaaca acacttgatg ccattgctac tagcatttgg
     3961 tcttttggca aactattaat tgggtcacta cttgaaagtg ctctgtattt tcttgaaatc
     4021 tttgcataga atgtatcatt acttaaatca gcatctgagt tattctttaa cattgaaccc
     4081 gtaaaatcat catcataagc tagatgtaat tgccataaca ttccaagcct ttcaaataca
     4141 ttgcttggta tacctaagct atttgaagtt acatgctcat atatcttatc cattgttgaa
     4201 ccttcaagtc ttgaatgtgt cttatcatca aaggtctgag caagtaaagc aagtacattg
     4261 ttactagttt cgctatatgt catctttcca atatctgtaa catgtcctat ctcatgacct
     4321 attccccatc caaataagtt tcctcctgta gcttttccac tatcatctat ttggaaaggt
     4381 actccattca taagccctgg aactgaacca tattctactc ctacatgtaa tccagaagca
     4441 tacataaatg ctccaataaa cattctttgg tattttatgt tcatacgaga ttttggagcc
     4501 atatcatttt tagttaagtt aaattcatta tcatctacag ttccattacc atctaaatct
     4561 tgtgttttaa atactcctct ttctgagtaa actaaatcca ttatttgttc ccatgcaagc
     4621 atactattat ataatctatc tacttgtgta tttaaatcag catttccttt tgatatccct
     4681 tgatatactg ctgttgcagg aacatttaat gttactttat cactttcaat atctgtagtg
     4741 tttaacacac cagttttttc tgaatatcca tatgaattac caacatttgt tcctggataa
     4801 tatggttctc cttttacagc atctttatat ttagctaatt cttctatata tgcttttatc
     4861 tttttcttag attcagaaac tcccgcagga ctcttatcat ttattgttcc atttagatta
     4921 agatgtggta tcttagtagc tcctgctaca cgtactttta tatctcctcc acttggagta
     4981 tcttcagcgt atcttatgta taaacttcct ccacattcta tatctaaact atgaagtttg
     5041 cttaattgaa ttacattttt tccagtgtta agatttattt ctccactctt atatgcacca
     5101 gattctccat agtactgtgt atatatcaac ttaggagttt ttccactttt acttccaaca
     5161 tatactgtga tttcatctcc tgctctagca gctactccta atgcctgcca gtcattttgc
     5221 atacctaaat tattggaatt tacagtatac tgtccatttt tatctttata ttttcctaat
     5281 ttatttattt cttgatttac agtcgttaca tcagtaagtg tggctctatc attatataag
     5341 tcttgagcta attttaattc tctctcaata actgtcttat atggatgata ttctccacta
     5401 gctttatctg gagtatttaa tctatctttt aattcagtta ttttttcttg agttacatct
     5461 tcttttaatt caacttgtag gtcatccata aatagatttc ttacatcatc ttctatactg
     5521 tcatactcat aaaacttaag ttctgatata ttagacttat atgaatagga tgagcaaaca
     5581 cttacttgta tcttggtagc agttattggt tcttttaatc taaccattac atacttatta
     5641 ttatttacag ggtctatctt tgtttcaaaa ggaacatccc ccagattgtg taattgacca
     5701 ttttcatccc aatatcgtac ctcaaagtca tttattgtct tatcagaaac atcaaaacga
     5761 ggtgtagcca taaaagtatc catagtataa gatttatcaa aagttattat tggccctcta
     5821 ttcgttccct cagctgcatt atatgttggg aatgtccaat gtgttgtaaa gtccccatct
     5881 actacattga atttatcaaa tggattttta tcactatatt cacttttgtc atatcctgct
     5941 ggataagtaa catctacaat gtgatttgtt ggtattccaa atccaccatt ctctttagga
     6001 gtattaatta atctatagtt aggtgttgtt ggtgcatcca tgctttcagt tgtacctata
     6061 tatgttttag acattccact agttcccaag tggttagtag ctgtcattct aacttcatat
     6121 gttgtattat ccttaagacc ttctatcttt gaacttgtcc cacgaataag cttatcattg
     6181 tattttatcc aagacccatt agaacctttt tctttatagt acaagtcaaa atctttagct
     6241 tgtttatgat ttttccagct tacatcaaga gatttaaatt tacctttaac atttatacct
     6301 tctggtggtt ctggttttgt gtctggaaca acttgaaatt ctaatatact atctgggcta
     6361 aattgtatag gtttatagtt tgaatctaca ttttctggta ctccgtctaa gttttctggt
     6421 gttgcatctt tataaccact agaccaatct ccatttaaag attgtatgct aaccctatat
     6481 agtccatatg cttctatatc tctaacttct attgtatttt tactagtttg taatttttta
     6541 gtagataata cttttccctt actatcaatt ttgtctagta taagttcgta tgctgataca
     6601 tttacttcat tattccaata aaaagatact ttttcatttc caacagcagt gctagtcaat
     6661 attttattta ttttaggtat attcatctct ggctttggta tttctttata tacattgttt
     6721 aaaaattcaa cttttgatat ttctgcaaga tttctatcat ttgctgttgt agctgttatt
     6781 tttatagtta tcttttttac tgctacttgt ttaccaagat ttattactat atcactattt
     6841 tgaacatctg catatgtttc taatgctgac ctactatatg tagatgttgt agagttatta
     6901 tctttactga tattaccctc ttcttttgga gtatcttcat ctgaattagg tttatccatt
     6961 gatgaatttt ctttatcatt atttttatct tgattggtat tagagtttac ttcttgttta
     7021 tcgctatttt cctgttgttc atcattattt tcatctttat tatttgagtt attatcagtc
     7081 tggtttatat tttcatcttt attatttact tcttcttgat ttacttcttc ttgttcgtta
     7141 tttacttcct cttgttgctc ctcatctttt aagtttttca tatattcttt gttttcataa
     7201 ggaatctgtt gaacattacc atctttgtca gtaacctcaa ctattccttt tgctggagca
     7261 gtaccttctg gagcttttat attgatgact tccatattaa gtgcttctga taaagctata
     7321 tccattactg ctggtttttc ctcagatatt tcatcatttt ttgaagatat tgtaactcca
     7381 ttattttctc cactaaataa attttctaca ttaccattaa tatctacatc actatttcct
     7441 tttaattcaa ccttacttgt atctactata ggattggtag atactatact ttctaggctt
     7501 tttgcatctt cactttgtcc taaatttttc tgtacataat ctaagtcaac aatatctacc
     7561 tttccatctc tatttaaatc aaattctctt ttatttgaat ctatattctc taaaacctta
     7621 ttataatcac tcttatctac tttaccgtct ccatttacat catccattaa gaacaattca
     7681 taatttaaag gtttattttt attatctaca cttgctctat tgcttaataa gactctttgt
     7741 gaataacttg atatatcaat gtctttaatt tctttgttct taaatccagc tccagagact
     7801 tctacattgt attttccaac aggtaaatta ttaaatacaa tattataata tgatatattc
     7861 tcatctttat tttttatttc acttctactt gcagataatt tttttatagt atattctata
     7921 ttatctgttc caacatttac tgttcctgaa tctttttctc caagctttat tattccacta
     7981 ttgttactat catcttttaa tcgtaactgc atattagtca tactttctga ctcgctattt
     8041 tttattggca gtgaaaaatt taaatctact tcaagactcc cccttaactt ttctgtaact
     8101 gatttttcaa ctgcccttag cttcccctct aatataggtt ctgcaaaaac gtttagtggt
     8161 gcactacaca tagatactgc tagtacacaa gatattgcct ttttcatgaa ataacaatcc
     8221 tcccttaata aatatctaat ttttcatgaa tttaaatact ataagtttca gacaataaaa
     8281 aaagacactc aaagagaatc ttaattataa aataaaaaga ctttactctt tttagcaact
     8341 ggctgatatg gctttaaaag ctttaatccc tatagttttg cgtcattaga tttccctaat
     8401 tttgccattt aattttcact actttcttac ccattttata ctatatttaa actttttaat
     8461 acaatttttt tagattaaat tataaaaaaa taacatttat attaatttat taatataaat
     8521 gttattttcc attataattt aattatttat atagcttcct tacaagcata attttgtgta
     8581 tattttctta ttctttatat cttccataaa attcatgtgt agcatataga ttcttatctc
     8641 ctgttatagc tataccaaat cccattattt catacccttt atgcaacatg ttagttcctt
     8701 cttctggatt tgtcttccac tcattaaaaa taaagtttcc tatatcatct gcatctctat
     8761 ttgtatatac aggtttatct ggaattttat atttaattat attttcacct tgaactgcta
     8821 tatatccagg tttaatctca ctccaatcta agtatttcaa aaaagtagaa tatgaatttt
     8881 ttccatttat cgtatgagat aaagtcttct tatttgccat taaattagac caatcatttg
     8941 ctaaaccctc taatctgctt gctacagata acgctcttac tccattctct tttctatact
     9001 gctttgtaag agcatatact ttacccttta ttctctcttt aaatgctcta tcatttggat
     9061 tgtaatataa accttgttga tttggtgaag cttgatttat acattgcttg ataacattct
     9121 gatttatgcc tcctagtaca gtcaatttgt ctgcaccact taaaatactc ttgttactgc
     9181 cattttcaac taaaactaca ggagcatttt ttgctattgt agaggcagcc aaagcgtctg
     9241 ttaattgtaa gcctttactt agataaaatt ctttactatt tttataaaac tcttgtataa
     9301 ctatcttatt agtttcaaat ctatctgtgc cacccaatct aatagaattt gtgctcttaa
     9361 ctaattcgtc gctgattatt tcactagaac caagcgcata actctttaag cctgtcgtgt
     9421 caaatcccac actatttcca tctgtaagta ttataggtac tccatctcta gcagctactg
     9481 gtgatgcact tatcgcatct gcttctcctg taaatccatt ggctataatt actttatcta
     9541 ttggcttaat ttctttgatt ttttcagcta tttttatact tgtatcaaat ctattttcac
     9601 caaagattct ttgtacaacc ttctttttgg atagtaactg attctcaaca tttttactta
     9661 ttgttgattc tgagcctatt atatacacag tctttgcttt gtttaatctt tccatagttg
     9721 tgtttggaat ctggttttgt tttgtcatca aaataggcgc atttaaggct ccagctaaac
     9781 cacttgcact tagaccatct gctaagctat tatctgagtt gactagtatt gctgtattgt
     9841 agttttgctt atctgctatt tttgctgctg tctcgtatct gtcattccct tttatttgct
     9901 caactgatgt caacgcattt accataggag tatttaccat tactaaaaat agtgtaagtc
     9961 ctatagctaa tatcttttta ctattcttca tattattttc tacccccaat gtacttttca
    10021 tattttttat tagtactcat acttattttt aatcaaaagt tacaattttg ttaccatatt
    10081 ttatatatga taccatagtt atccatacaa ctcaaacaat atacctaaag tttttattct
    10141 ctataaattc aaaacattat aatttatttt atttaattaa gttataagtt caaaataatt
    10201 tatgttagta atatgtttaa tcattataag aagtatcttt ttataataat ttttgcaata
    10261 tgaatttctc aacattataa tcaaaaaata aaataaggta tctcaatcta attctaaatg
    10321 agacacctta tttttattat tttatcttgt tatttgtata ttttataata tctacactat
    10381 gtcttacata ttaacgcatt gtataatcat atattatcta aataaacttt taatattaat
    10441 tcctatatct tattagttct tagtaaataa gtttattttt tctgctattt tttcaatagc
    10501 gtttttagct attccttcac ctatttgtac taacttagta gcattcttaa gtcttaactc
    10561 aactacttct tcttgtgatt tagaaagttc ttctgtagtt aatactattg gagcctttga
    10621 actagctgca agtggtgctg ctgtaagtgc atcaactaat tgtccatttc cacctacata
    10681 accatctttt gctacatatg ctttagttgc acctgcatag tatttattga ttactttagc
    10741 attagtatct tttctatttt ctccagctaa tctttcaact ttattattta aatctatatc
    10801 aactaatttg tcttcaactt cttttgatac agaattttct ccacccacta tttctaattc
    10861 ttttcctttt aataattttt cagcatttgc atctaattcg ttacctgtaa ctattattgg
    10921 agcaccaaat tgagcagctc tagctgatat actcatagca tcagcttctc catttccacc
    10981 tactacaaaa gcagtcttaa atgtatcttt taattgtttt gctatttcta aagaagtttc
    11041 aaatctatct tctccagaaa ctctctcaac tttacttaca cctaatttag aaagtttttc
    11101 ttcagtttct tttgatactt tagattctcc acctactata tatattttct tagaagatag
    11161 attacttcca agtactctta atatttcagc ttctatttct gatggtagtg aatctttttt
    11221 agataataat attggtgcat ttttttgaga ggcaagtggt gctgatgcta atccatcaac
    11281 tatagcatct tctccaacta aaattatagc ttctgcttct ccatctttga atctctcttt
    11341 actaacttct actgctgttg taaatcttga atcaccagat aaaacttcta cttttaattc
    11401 ttttccacct tttacatcag ttaatacttt gtgtaagtct ctaactaact tatggttttt
    11461 acttgaaaca cttattgttt ctggcttttc atttgccttg cttaaaacta tatcaaagct
    11521 tgatttttct ggtttatctt tatcatcact atcttcttgt tcttgagtaa ggattgcttc
    11581 attttcaaat gttaaagcat atccattttt aactttatta actatttctc ttcctaatgt
    11641 agttaatcta attccgtcaa ataattcttc tgctgatatg tcttgtaaat ctgcgttttt
    11701 aactgttatc gtatgtaatt cttttgaatc tatgtcacta taactctttt cataaccttc
    11761 aaaagtacct tcttctgatg ttatcacttt tgagaaatct aaatgttggt ctcctacatt
    11821 taatgtaata acatttgctg aatcttttgc tctttttact tcaactgtat ttgtagattt
    11881 tatagttgct gttaacttgt tatcagaatc ttctgctaaa gttgcattgt aagcattaac
    11941 tgcatctact atttcttgag cagttttgta gttttcaatt ttatagtcaa ctacttttcc
    12001 acctaacact tgatgccctt tatcttgaat agtaactttt aaactttgcc cttctgttaa
    12061 agagtttatc ttattttgta attgagttgc attagttaag tttacattgt ctacttttat
    12121 atcgtaaact ctatcattta catttgctcc tgcttttgta tcttcaaact taacttctaa
    12181 tgcttttcta acctcttcga ttagtttagc agaatctttc gcacttactg tgtaattttt
    12241 atcaacattt tctgtcacag tattgtctgc gaatattggt gctgctgcac tcataactgt
    12301 agcacctgcc attactattg ccatacttct ctttttgttg cttaacatat ttatgtcctc
    12361 cgaatattat tttttatttt ttatattcgt atttcccaca cataaataat attatatata
    12421 atattatttt tcaatatatt ttatgtgttt acataattta ctaacacaaa cactaataat
    12481 atcttcttga accccttccc cctgcttagc tctctataat tatgctcaaa gatagaaatc
    12541 cctattttat agtgattttc tactaaacaa tcatatacta acaaaagtat tcaaactcca
    12601 tttttatata ctactatgca ctaatttttg ctttactctt attacttaaa tatatatcac
    12661 taaattaata tctatctcca tatattaaaa tatataacat attataaaaa tcatcataaa
    12721 ttagagttta aaattaaaaa ttattctaat acatgtaatt gataaaaaat aaaatataag
    12781 agtagctact ttaaaataaa tgttcttata tgattagata tttttgcata attaaacgat
    12841 aagaaatcaa atttaatttt acataaatag aatatatatt tttatataat aattgaaaat
    12901 aaaagaggat acctcataat gataaaagaa tcactttgag ataccctctt acaaacaact
    12961 aaatcaataa ttttctatct ttcacactct tgatttgcaa ctgtacaaga agttttacaa
    13021 gctgattgac aagaagtttg acactctcca catccacctt ttgcagcact ttgctttaaa
    13081 gtagcttgag ataaagtttt tacatgttta ttttccattt tcaacgcctc catttctaat
    13141 tgtttcctat tgattatatc ataaaactac tttaatataa actctattta aagttgacac
    13201 ccaatacgcc tccaatgcct cctgctgctg atattagcaa taacttataa atcatcccta
    13261 tttcaaatac aaacttttct tgtgctaaaa acacagtcaa aaaaatacat actatgtaca
    13321 aaagtcctac taaaagccca tacataagtc ctttttcttt catgtgtttt gaagtgtaaa
    13381 accctcctat agctgcagaa atagtagtta taaatgatga gaccatagtt atattatctc
    13441 caccaatatc tgtaaatgtc aaaaataagt tatacactaa taaaacagcc aaagttatta
    13501 tatatgcata tcctagacct ttaaaaatat aattagattt tcccataaaa aaacctcctc
    13561 tcaaattaat atatattcga gaaaaggctt ttaaattact aatttagtct tcttctattt
    13621 cttctttttt agatttaaca gttcctatag cccatttttc aaatggaact ttagttctat
    13681 ttggtcctaa ttctaatatt acaacatcat cttcaacttt agctacatta gctactattc
    13741 cacctattgt aatgaccttg tctcctacac ttaggctact tctcatttct tttaattgtt
    13801 tgtctttttt cttttgaggt ctaatcatta ggaaataaaa gattgcgatt actactaccc
    13861 atagacctat actcataatt atttgttgct gtggcattaa tttttcactc ctttgtaaat
    13921 tatactcttt tgtaaatcat aataaatgtt tatataacaa tttactttct ctatctttga
    13981 gtactattga atattatata ttaaaatgat tataattaat agtgcaaaac ctatatttca
    14041 tatccatatt ttgcaaaaaa ttcatttcta aaatcaagta atctatcttc cattatcgct
    14101 tgtcttattt gtttcattaa atttaataaa aagtgaagat tatgagtagt tattaatctt
    14161 gcacccagta tttcatttgc ttttataagg tgtcttatat aagctcttga atagttttta
    14221 caagcataac aatcacattc agggtcaagt ggagtaaagt cttcagcata agttgcattt
    14281 ctaactacta ctttaccttg gctagtcatt gcagttccat ttctagcgat acgagtaggt
    14341 aggacacaat caaacatgtc tactcctctt ataacacctt ctactaagtc atctggacta
    14401 ccaactccca ttaggtatct tggtttatcc tttggcataa gtggagttgt atgctctaac
    14461 acgtcataca taagtggttt tggttctcca acactaagtc caccaatagc atatcctggt
    14521 aaatcaatat tagttatttc ttttgctgat tgttccctta agtctttata catcccacct
    14581 tgtattatac caaataaagc ttgcttgtcg gtattattat gggcatcttt acatcttttt
    14641 aaccatcttg ttgttctttc taaagaattt tttacatatt ctctatctga tgggtatggt
    14701 gcacactcat caaatgccat cattatatct gaacccaatg cattttgtat ttccatagct
    14761 ttttctggag ttagaaaatg ttttgaacca tctaagtgtg acctaaattc tacaccttct
    14821 tcttttatct ttcttaaagg ccctagacta aatacctgga accctccact atctgtaagt
    14881 attggtttat cccaattcat aaacttatga agaccaccag ctctttttat aagttcatga
    14941 cctggtctca tatataaatg gtatgtgtta ctaagtatta tttgtgaacc aatctctttt
    15001 aattcttctg gtgtcataga ttttacagtt gcttgagttc caactggcat gaatattggt
    15061 gtttcaataa tcccatgtgg agtgtgtaat cttcctaacc ttgcaccact ctgcttacaa
    15121 gtctttatca attcgtatct tactgcgtac ataaagttct ccttaatcat atttatttct
    15181 cattatttct taagatatat ttgtaataag ctattcatat aatttattgt ctaaatagat
    15241 ttatcttcgt cttctttgtt ctgttgttcc ttaattgctt cttcatcatg aatactcatt
    15301 atattaagag cactcttgtc ttttgttact aaaaactttt ttatagcaaa tagtcctgct
    15361 atagctataa ctcctattaa aacatctatc ataccttcat ttttaggcag tagcaacatt
    15421 tttctagcta ttgcgtaaag taatgcctca ataaatgctc ctggtatatg aagagatagc
    15481 attactacaa gttcaacacc tattactaaa agtaatattt gtgctaaaaa atcattaagc
    15541 tgactgtatt gtactggatt ttgaaaatca actatatatg ctccccacat aagtcttaga
    15601 acatctatag ttcctaaaaa tactgctatt agaactacta ctgctaaaac acgttcaaat
    15661 ataaaagcaa tctttaatat agggttattc tttttttgtt tttgtaaact atgcatccat
    15721 tacctcccta ctttataatc atagcatctc caaaactgaa gaatctatat ctttctttta
    15781 ctgcctcatt atatgcattt aaaacattat cctttccaca aatagcactt actaacatta
    15841 ttagtgtaga ctctggtaag tgaaaattag taataagttt atctaaaact ttaaatttat
    15901 aacctggata tataaatatt tctgtccatc cactagtttc tttcatcttt ccatcctcat
    15961 tacaagctga ttctatagtt ctacaactag tagtaccaac acatattaca ttttttccat
    16021 tttcctttgc tctatttatt ttgtcagctg cttcttggct aaccatataa tattctgaat
    16081 gcatcttgtg atttaaaaca tcctctactt ttactggtct aaaagttcct aagccaacat
    16141 gtagagttac aaaggctata tctacacctt tttcttttat tttatttaac aattcttctg
    16201 taaaatgtaa tcctgctgta ggtgctgctg ctgaaccatt atgctttgaa taaacagtct
    16261 ggtatctttc tttttcatct agtctagcag tgatatatgg aggtagcggc atatttccaa
    16321 gttcatccaa tatttcttca aaaattccat cataatggaa ttttataatt cttgaacctt
    16381 catctgataa atctacaact tctccaatta gctttccatt tccaaaagaa aatttagtcc
    16441 ctacttttgc tctttttcct ggttttacta aagcctgcca agtatcttcc tctgttcttt
    16501 ttaataataa aaactctatt ttacctccag tttcaagctt ctctcctatt aatctagctg
    16561 gtataactct agtattattt aatactaagc aatctcctgg atttaaaaat tctattatat
    16621 ctctaaatac tttatgttca atattacctg tctctttatc taataccatc aatcttgagc
    16681 tagctctatc ttctatagga acttgagcta taagttcctg tggtaagtca aatttaaaat
    16741 cacttgtttt caatgttaaa cttcctctct taaaatttct ccagctacaa taatatcaaa
    16801 aaaacaactt attttccaca atattaccat aatctatcaa gaaattgcta tttttaacag
    16861 acaccatatc cacaatatat agatattttt ccacgatata catgtcttat ccacaatata
    16921 tagatacaat acacacaatt tttatcgtgt ttatccacag tatctacaga tataattacc
    16981 attttgtgga tatgtttgaa tttttagcca ttttagaaat attttaattt aatgactctt
    17041 ttattttata aatactcgta taatctattt ttatttttca ttaggatatg gaatttttaa
    17101 gtgttcatat gctaatggca tggctactct tcctctagga cctctattta taaatcctaa
    17161 ttgaagcaaa tatggctcat atacatcttc tattgtattt ctatcttctc cgatagaagc
    17221 tgccaatgta tctaaaccca ctggtcctcc tctaaatttt tctattatag tcataagaag
    17281 cttctcatct acaaaatcga gacccaaact atcgactcct aaaagttcca gagcatcttt
    17341 tgccacctta tcagttattt ttccatcagc tctaacttgt gcaaaatctc taactctttt
    17401 tagtaatcta tttgctatcc ttggagtccc tcttgaacgt tttgcaagtt ctaatgctcc
    17461 attagactgt atctctgcat ctaagatgct tgaagaccta agtactattt ttgaaagttc
    17521 atcaactgta taatagtcca atttacaaat aacaccaaat ctatctctaa gtggatttgt
    17581 aagcatacca gctcttgtag tagctccaat aagtgtaaat ttaggaaggt caagtcttat
    17641 gcttctagca gatggccctt tccctattat tatatctagg caaaaatcct ccattgctgg
    17701 atataaaact tcttcaacac ttctattgat tctatgaatc tcatctataa ataaaacatc
    17761 attttcattt aaattcgtaa gtatggctgc caaatctcca gctctttcta ttgcaggtcc
    17821 tgacgtaatt cttaaattta cccccatctc attggctatt atacttgcta gtgtagtttt
    17881 tccaagacct ggtggtccat ataaaagcac atggtctaac tgctcatttc tcgatttagc
    17941 tgcttctata aatatactaa gttgttcttt ggatttttct tgacccaaat aatcttctaa
    18001 agtttttggt cttaaactgt tttctatatc tatatcttcc atcttcattg tagaagttat
    18061 tatcctattt tcatcttcaa aaccttgcat ttatacccct cctctcgtac ttttgaaaat
    18121 ctactttata tattttcaaa tttacataaa ctccttaaat attgttttaa aatccaaata
    18181 ttataaaatc caaatactat ttcaaggatt tactcattat atatgtaagt gctttcttta
    18241 taatagcttc tgtattcata ccatcttttt tacatttttg aactgcctct tttgattccg
    18301 acaaagtata gcctaaagct acaagtgcat ctacagactc atcttgtgat atcaaggtag
    18361 gtttttgtga taataacgtt ggttcaaact ctatgttatt tttgtctacc ttatccttaa
    18421 gctctaagac gattctttct gctgtctttt taccaacacc aggagctttg gataattttc
    18481 caatgtcttc acttaaaata tatgctccta actgtgctgg tgatgcaaat gatagtattg
    18541 aaagcgccac tttaggtcct attttagata cagatgttag taattcaaac atcttaagtt
    18601 cttccctact tacaaaacca caaagactca tatcatcttc tcttacaatt aatttagtat
    18661 atatttttgt ggcttctccc acttgtaaat tcattattgt attggatgat acatttattt
    18721 tatatcctat cccattattt tcaacaacta tactgtctat ataaatttct tctactgtac
    18781 cttttatata actatacata cttaccacct atattcttta gagttttttc aagtttgttt
    18841 gaatgagcat ggcaaatagc cacagctaaa gcatctgcaa catcatctgg ttttggaact
    18901 ttttttagac ttaaaaatga agttaccatc tgttgaactt gtgccttatc tgctctccca
    18961 tatccaacta caccttgttt tacttgaagt ggagtgtatt catatacagg cttcccatta
    19021 tgagcacatg caagcatagt aacacctcta gcttgtgcaa ctgttatagc tgtttttaca
    19081 ttcttgttaa agaataattc ttccattcca acttcatcta tattgtaatt ctttactatt
    19141 gtatcaattc ctttatacac aagttccaat cttctcgata tattcatatg ggcaggtgtt
    19201 gtaactgctc cataatcgat tgctttaaac ttgctatttt tgtattcaat tataccatat
    19261 ccaactatgg ctatacctgg gtcaatcccc aatattatca ttttttaaaa ttccccctaa
    19321 aaataaaaga aataccaaaa tgtatttctc ataaaaactt atgttctaaa tcattatatc
    19381 ataaataata ttaacaaatc ataaaatgct ctatgtaaaa tataaaatca aataaaaaag
    19441 ttatatcaaa gcaagatttt acctcaatat aacttttata tttattacaa ataaattatt
    19501 gtatttttat aggaattaaa tgtgactaca attttaatac taatctattt aatattaaat
    19561 tatttattat taatttactt agtatttaac ttaaaataat attaatttac tattaacttg
    19621 caaagtcttc taatcttgaa taggcctctt cttcagtatc cataactaca ccttttttga
    19681 tttcatcttg aactgtttta ggaagtgaat ctactcttat ttttgttttt tctactaatg
    19741 ttttacttcc actatcatca tatttatata gtgctatatt tccattatca ttttcaatag
    19801 tatatttacc ttttatagta acatccattg cttgtacatc tttattatca ctatatttag
    19861 attctaccaa tatgatttca tttttatcca tactctttat ttttttagtt ggatattctt
    19921 ttttaaaata tgatactatt tctgacttcg tcttatctaa taatgactct gggactattc
    19981 ctgccattgt aagtgttctc ttatagttag tttcattttc gccttcactt tgaagccaaa
    20041 cttcacaatt tttatttaat ccaaaagctt cttttgactt ttcattcata ttcgcactag
    20101 tacttacaac ttcaccagtt tgaactccat tgtgttttaa tcttgtccct atataaactc
    20161 cgctacttaa tacaaatact ccaaccagta ttaaggcaga tattttccaa ggaaataatt
    20221 cttttttctt cttttcaaac attgattacg cctccttttt ctattatttt ctccaagctg
    20281 taagttttta tacaatttag gtaaatttta gaagaaaata tatttatatt tcaaattact
    20341 ctaagaatag atattttcta aaaggtagtt ttctcttaat ggttatattc ttgtaattat
    20401 atggacataa tttataataa ataatcgttt aggaggtaat aactttggaa agaataaact
    20461 gtaatgtaat taactgttca cataacaaca gccatatatg ttatgcagat aaaattttta
    20521 taaatggtga aaaagctcac aatgacagac atacttgttg tagttcattt ttagatgaat
    20581 ctatttatag taatttatct agcaacgtta ataatagaaa ttgtgaggaa ttagtttgta
    20641 ctgtaaaaaa ttgtaaatac aacaaagatg gtagcttatg tacacttgat aatatattgg
    20701 ttgctcctga aactgataga gtaaaccttt atattgaaac atgttgctct agtttcgaat
    20761 gtaaatagtc atagtataaa tataagggtg tcaaatgtaa ttaaactaac atagtgtaga
    20821 gtatctacaa ctattagttt gattatactt gacaccctta tttattttaa ataaaatttc
    20881 attattataa ccatgtttat aatgttctaa ctgtaattaa atttgataaa tttctataaa
    20941 ttggtataat caatatgtaa attgaattta gtaaattaat cataaaaata aaatatcgag
    21001 tatatagtgt tatactaact agaaatgagg tgcttatgag tacattttat attcaatttc
    21061 tttattttgt aatttatagc tttataggat ggtgttgtga aactacatat tgttcagttt
    21121 tacaaaaaca atttgtaaat agaggttttt taaatggtcc attttgccct atatatggat
    21181 ttggagcatt agcaatagtt gctaccttga ctccttttgt acacaatatt cctttgttat
    21241 ttttgtttag tataattata actagcataa tggagtattg tacgagcttt attttagaaa
    21301 aaatatttaa tatgacttgg tgggattatt ctaaacataa atttaatatt catggaagag
    21361 tttgtctgga aaactcactt atgtttggtg tattatcatt gattgtaatg cttatagtac
    21421 atcctattgt ggttgacttt attaactcta tctccaaaaa tgtgctattt atatttgcta
    21481 tatctataga aatttatttt gttttagatt tagttatcac agtccataca attttacaat
    21541 taaatggtaa gttaaaacaa atcaatctta taattaagga attaaaagat aagaaagaat
    21601 actacaaact tattacacaa gaaactatag aaagcaaact tgaatcttta gttgaaaata
    21661 gactggatac tttggaagat aggtttgaaa tacttaaaga aaaagaaaat tatcgctatg
    21721 ctaaaaatcg tattgatgag ctaaaaaata aacttaatac tttgctgtct aaccacaaat
    21781 tacttcatag acgtataatc aaagcattcc ccaacataag ctctaataag catacagata
    21841 ttttaaataa aatcaaagaa aatattaaat caattaaaaa agataaataa taaaataaac
    21901 acataagtta aataataaaa atactaatac ataagattaa ggtttagaat attttttgta
    21961 aaatactcta aaccctaatt aatatactat tatttttaat cttaatttat aattttagtt
    22021 tattttaatt ttaactcagt aaatttaagc gtttaaactt caatacacta atatactacc
    22081 ccatcaatat ctcaactgat tctctaagtg tgctaatctc tcccacattt ccagggaaaa
    22141 ttatatatgg catattagga aatttgcttt ctttgcctgt catccatact ggtataccag
    22201 gttttatctg tcccattact gtagcttttt ttactcttag tgctttagta ccaacatcac
    22261 tagaagtaat tccaccctta gctataataa aatttggtct tacattaagc atactaatta
    22321 tactggtaac tgcatctgat atttctacag aaatcataag ctgtttatct ttatcattcg
    22381 tatccaagtc aaaacgctct cgtctagtat aaacagcaac agttttacca ctgcttattt
    22441 tttcctctac aacttttata actcttttta cctcattttt taaaccattt tcctgaagaa
    22501 ctaaatgttg attaaattct ataaattcta tcggatattt acaattttta agttcttcta
    22561 actgttgggt agtcttattc acatgtgaac caacaagtat aattcctcca ttggtattac
    22621 cttttgatac taattcatcc ttagtaagca gttccttgtc actcactccg ccaagtattt
    22681 ttgttatggc agcagcgctt ctaaacataa attccttacc actatttact gctcgtataa
    22741 acgcaattgt aaataccttt acatctacat agtcggttgc atttacaata attttattga
    22801 atccttcagc ttttttaagt ttttctgtta tagcttcaat atttagctct ctaagttctt
    22861 ttgacgaaat atatatcata tcactagatt tgtactttcc ttttgtcttt tcttcacacc
    22921 actcacctat atcagatgat ttatatccaa aagatttatc ttttgcaaat tcagtcattc
    22981 ctgctggtac aagtatttct ccttctttaa cataatgtac attatctata gtaaacctac
    23041 caccttcttt aaaaaatggc attattattt caccctgaaa taacttcccc gataatctct
    23101 ctacttcgct ttttaataaa ttagtttcaa gaggataatg tcctctcata gtagaatcac
    23161 tacgacttat gattataaaa tccttattaa ctttctttga tacatccaca atattctttg
    23221 aaatttcttt atgtgctttt gtagtttgag caacagtaaa tccccttgaa ttggtaagta
    23281 taaaaaacat actatttttc tcattaaaac cttgttccat actatcctta tcccaatcag
    23341 tataaacaga aatatcatga actgtttgta cacctgttgg gtcatcatct aatacaacaa
    23401 tttttctatc taaatgctta agctcatctg caagaagttt atttaatcta tcctcatcta
    23461 cttgtttaaa agtattaagt atatctatgc taattggttt tacttctctc atttaaaacg
    23521 cccctttatg taatttgtat agtctaaatg taatttatat gatataaaca atagtttgtt
    23581 atttatagac ctggaagtgg tataattcca tttataacac taagcaataa aaccattata
    23641 aatgctacaa ctccagcaat ggttcctcca attgtccaag agtttaaagt atctttaact
    23701 gataatccac taaatcttga aagtacccag aatccagaat catttggaag ggagaaacca
    23761 actcctccag cacatatagc aagccctact aaaactggtg acattccagt tgccaaaatt
    23821 gtaggtccta aaattgatga tgttgttact aaggctacag tagcagaacc ttgagaaatt
    23881 ctaagcaagg cacttaataa gaatccaagt actacaactg atatactaag accagacata
    23941 gtatcaacta agaagttacc tataccactt gcatttataa cactgccaaa cgcaccacct
    24001 gaccctgtta tcaataatat tagccctgct gaatcagcag cttcaataac tacatctccc
    24061 ataggtttat ttatgtattt ctttaaaaat cctattgcca ccaatattcc aagaagtatt
    24121 gctatgtttt tatctcctat aaatgcaagt actccactca ttgtagaacc tttttctaag
    24181 aacatactaa atacatttga tataagtata agaagtattg ggaacaataa agaaaacata
    24241 gaaattccaa aacctggtac tttagaagaa tcatcatctt caatttttat gctatctttt
    24301 ccctgctcta aatttttttc tctatcattc tcatcaatag cataagctgg atatttttca
    24361 aaacgttttc cataaatcca tccacctata agagctgctg gaaaagcaac aattatagaa
    24421 taaagtataa aactacctac atttgcattt acatttgctg caactgccaa aggtcctggt
    24481 gtaggtatta caagtgcatg acctactata gtcccaactc ctaaggcaca tacaaaaacc
    24541 attagagatt tcttagttac tctcgaaaca tacttaatta taggcatcat tataacaaaa
    24601 gctgcatcca taaaaactgg aattgaaatt aaaaaacctg ctgtagttac tgctaaagca
    24661 ctgttttttt ctccagtctt agctaacaac ccctttgcaa tagattctgt tgctcttgat
    24721 tctgaaagaa tatttccaaa tattattcca agtccaatta caatacctat actacctaat
    24781 gtatttccaa atccagtcga tattgtggtt gatatttcat ttataggcat tctaaccata
    24841 aagcctgtaa ttatagatgt tatcagtaat gccaaaaacg gatttacttt aaatttaata
    24901 atcgatacaa gtaaaattcc tatagatata acaaatgcta tcaaaagtcc atatcctgta
    24961 atcataatct ttaccccttt atcattctac tttattattt atcaatttta tttttctttt
    25021 actatgataa cttaacctcg ctgtatttat ataatctaat cctaataata tgtatttaat
    25081 tatattgata tatttaaata ttaattatcg tgttttttta tttcaacacc tgccaacttt
    25141 tcaaaatact gtgctattcc actatggtca tcttccaaat gtccatgtac ttttaatgtc
    25201 tgcataattt ctaataattg acttgtcata ggtagtggta catctaaatt gtgtgctgtt
    25261 tgcattacat tcttaatatc tttcaaatta atagatattt ttccacctgg tttaaaatca
    25321 cgattcataa tcattggtat cttcgcatcc aatattgtac taccagctag gcctcctctt
    25381 attgccttat atactttttc tgggtctgca cctgcttttg ctgcaagtac aaatgcctca
    25441 gaaactgctg ctatcgtcaa attaactatt acttggtttg taagttttgt aacacttcca
    25501 ctaccattat ctccaattaa aatagatgag cttcccatta tattaaaaaa tggctctact
    25561 ttcttataaa tttcttcctt accaccagcc ataaaagcaa gtgtaccatc aatcgctttt
    25621 ggctcccctc cacttactgg tgagtctata aattctaagc ccatatcttt taatttattt
    25681 gcacacaata ttgattctgt aggagtaact gaactcatat cgactactat acttccttct
    25741 tttaaagttt ttgccaatcc atccatccca aacaatatat cctgcacaat agttccattt
    25801 ggaaggattg taaatacaat atcacattct tgccccattt ctaaaacact tgcgtatttt
    25861 gctccacatg atataagttc atccacagca gatttattaa tgtcatacac caaaagatta
    25921 catccatctt ttaataaatt ttttgccatt ggctttccca ttattcctaa tccaataaat
    25981 cccaatttca ttttataacc ctccatatct tcacactttt gaaaacgttt tttatgtttt
    26041 agagtatact acataccagt ataccggtca atataaaata taaaagtatt tattttaaca
    26101 ataaatagta atttttaaag tcatttatta tatttagtca tcctatataa gttttaatac
    26161 atactattgt tttcaaatat aatatactgc ttttacagtt ttgtatttta actaatttca
    26221 attagtttta attaatctgc ctttaatgtt aatcatactt cacacttcaa taatttttta
    26281 tattttttaa tcttatctgc aatttaaatt gcaaaagatt gaccttattt tcactatgtt
    26341 gtatgcttaa aattatataa gtttttgtat ttttatattg tttagggggt attattaagt
    26401 atggctacat ttaaaagatt acaagaacaa gcatatgact acttaaaaga attgatacta
    26461 tctggagaaa tgatagaaaa tgaaatatat tctgaaacaa aacttgctag tgaaataggt
    26521 atctctagaa cacctataag agatgctctt caaagactta gtcaagatgg atttatagat
    26581 ataattccaa gcaaaggatt tagaatccat caaattacag caaatgaaat tgtagagata
    26641 ttccaaatac gctctgcaat agaaggattt tgtacttttt taattacaag tcaatacaaa
    26701 gaagctagag cagtagaaac tataagtaaa ttaaaacatc ttttagataa acaaaaagat
    26761 attttattag gtgataaaaa tttaaactca tttgcagaat acgatacatt atttcacaca
    26821 actatagttt catatgctca aaatactgaa tttgacaaaa tgtttaacaa ttatatgtac
    26881 agaataaaaa aattagctct cgattcattg tcacatgaag gaaggcttga aacaacatta
    26941 aaagagcaca cagatatttt taataatatt gcaaatggat gtattgaaga tatttacaga
    27001 actactctca ttcatatgga aactcctaaa tacattaatt tagaagattt ttgtaacaat
    27061 aagttatttt agcattatac cttcatttat taaaaatata tctatctcaa attaatttcc
    27121 taatttataa aaaatattct ataattatat tgtaactaat acttattcta aggagtgatt
    27181 tttttgaacg aagatgttgt aactaatgaa actatcgaca aagattatgc tattgaagaa
    27241 gttcgtatgg catgcaaaca ttttggtgat ttatattttt atttttccaa agtgttattt
    27301 gaagagtttg gtgaagataa aactagcgaa atattaagaa aagttttatt tgaaaggtct
    27361 gaagaaagag ctattgctat gagagagaga gctcatgaaa atggagatga attaatcgca
    27421 gacaatatta ttagcacaac tgatgttcca tttctaggat gggttcctga atttgaagag
    27481 ttacattgcc cctatggagc ttcttggctt ttaagatttg aggaaaatcc ttggtttaaa
    27541 aaatttgctt ctctttactg tgatgttaca gatactactg tagctgaagt atttacagga
    27601 gatacttccc ataaaataac aaaaaacatt ctatggggag ataaaagttg tgaaagaata
    27661 tatttccatg atgacaaggt atctgaaggt aaatatactt atggaaataa aaactgtaaa
    27721 taatttaaat tttctatatt catatactat attttgtact ttttcatata aatattataa
    27781 ctagtctttt attttacttt tgtttaacct aaagataatt tacttttaat ctatatgaat
    27841 tatcatataa ataatcagaa agttatcttt ataaattata gttttagatt tataatttat
    27901 aaaatattta tgttctttgt aaaatttttt agaagcttct aatgttatgc tataaaacta
    27961 tcttgagaag ggctgattga atgtttaata aaatatatga aaagaaagaa tttatagttt
    28021 ttcaagttaa aaaaggttat gtagtttata atactagaaa gagttttgaa gaaggtcata
    28081 cacatttaaa gcattttgaa gcagcaaaga cagctattga tttagcaata aataaaaaga
    28141 ttcctagaag caaagatgga tattatctga ctagtttaat tcgcataagt gatgatggtt
    28201 attacattga taagttaagc gaattgttat atgttagaga acaaaaaggt aaaaaagaaa
    28261 agtactgtaa ttctggttat cagatgtaac aagactagtt gtgaattata agtaccaatc
    28321 ataaatacct ttagtcttaa aatcaaagag tatcagtaaa tctataaaaa aacaacttac
    28381 tgatactctt tttaattata tgattaatat ttgaatttga tacaaaattt tatacaaaag
    28441 tttatattat ctattctgat tctttgtctg caaattggct attataaagc ttctcataaa
    28501 atccaccctt ttccattaat tcatcatgat tcccctgctc tataatactt ccattattca
    28561 taactaaaat caagtcagca ttgcgaattg tagaaagtct atgtgctata acaaaactag
    28621 ttctaccatt cataagattt ctcattgctt tttgaagcat aagttccagc ctagtatcaa
    28681 cagaactcgt agcttcatca agtatcaata ttgaagggtc tgatataaaa gctctagcta
    28741 tggttaaaag ctgtttttcc cctagagata tattagatgc ttcttcattt aaaaacatat
    28801 tgtatccatc tggaagagtg gttataaagt gatgaacatt tgctactttt gctgcttgta
    28861 taatttcttc tttagtagcc ccaaatctac catattctat attttcaaaa atggttccat
    28921 taaataacca tgtatcttga agcaccatac caaacattga acgcaaatct ttacgtttca
    28981 tatctcttat atctactcca tcaattttaa tagcaccttt ctttacatca taaaacctca
    29041 tcaataagtt tattaatgtt gttttacctg ctccagtagg tccaacaata gctaccatct
    29101 gaccactttt tacttctgca tttaaatctt ctattaaagt tgaattttct ccatatccaa
    29161 aattaacatg ctcaaatgta acatttcctt ttacattttc tatcttaact ggattttcaa
    29221 catcaggtat ttcctcttct tcgtctaaaa tttcaaatac acgttctata gctgcaaaag
    29281 aagattgtat tactgtagat aactgagtca tttgtgaaag tggctgattt atctgccata
    29341 tataacgcac aaatgcttgt aaatttccta ctgttattcc tccacttact gcatatatag
    29401 aaccgacaac tgccacagct gcaattccaa agtaagttac taatgaaacc ataggattca
    29461 tcatacttga tataaattgt gccttaaatc cattttcaca aagttcttga tttacttttt
    29521 taaattcttt tatagaatct tcttctttac catatagttt tatttcatta aatccagtat
    29581 acatttcttg tacttttcca tttaattttc caagagcatt ttgttgcaat gaaaatctac
    29641 tttgagattt ttttactaca aatttagata caaaataact aattggaatt ataaaaagag
    29701 ctataagagc catatatata ttaattgtaa acatcattga aagtgccaaa attatgacta
    29761 agattgagtt tacaatttgc ataaaactct gttgcaatgc atttgatatt gtatctacat
    29821 catttgatat acgacttaat acatctccaa aactattact atcaaaataa ctaataggca
    29881 atcttcttat tttattttcg acttcatttc ttaaatctct cattgtgttt tgaatagcat
    29941 tcgtaagtag aaaacttgaa gtatacgtaa aaattgcatt ggcaaaatat atacatgcta
    30001 aaatcaccaa tatttttgtt acataatcaa aatttacgga agcccctggt actccttttg
    30061 cgatactaat tacatcttta gtcaattgtg ttattatcaa tccttcagtt ttaggtgcaa
    30121 gtgcattcat agtagctgct gaaattatac atataatagc tataataaag gaaaatttat
    30181 atttctttac aaatggaaga agtctaccaa ttgttttctt aaaaccttta gactttttca
    30241 ttattctaat tcctcctttt ttaactgaga tgttgcaatt tcatagtata tttcacagtt
    30301 ttttaataat tctttatgag ttcccattcc tacaacttgt ccttcattga gtactataat
    30361 cttatcagca tcaataatag aactaattct ctgggcaaca atcaatacaa ttgcatcttt
    30421 tgtttccttc ttcaatttag cacgaagtat tgcatcagtt ttaaagtcaa gtgcagaaaa
    30481 actgtcatca aaaatgtata tttcaggtct tcttataata gcccttgcaa tagaaagtct
    30541 ttgtttttga cctcctgata catttgctcc accttcacta atcaattcat caaactttct
    30601 aggttttttt gatataaact catatgcttg tgcaactttt gcggaatatt ctaattctga
    30661 ctctcctgcc ttatgtttcc caaatctaat attatttgct atgctaccag taaaaagcag
    30721 tgatttttga ggtatgaatc ctatcttttt tcttaaagct tttaaatcat attctcttat
    30781 atctactcca tttatcttaa tgctaccttc tgttacatca taaaatctag gtatcaagtt
    30841 aattagagta cttttcccac taccagtact tcctataaaa gcgactgttt cacctgtttt
    30901 tgcagtaaat gaaatatcct taagtacaga agcttctcca tctggatagg taaaagttac
    30961 attatcaaat tctatgatac ccttattttc agtatcctta attccatttt caggattttt
    31021 tatcaatggt tcttcattta atagttcttt tattctattt gcagatacct ctgctcttgg
    31081 atacataata aataccattg aaaaaagcat aattgaaaac atggcatgga aaagatattc
    31141 caaaaatgca accaactgtc caacttgaag ctctccaata tttatcttct cacttgaaat
    31201 ccaaaataca gccaaaacag ctatatttaa cagtaaaaag aatgctggtt gagtaattga
    31261 cataagctta aatagtttct tagaaacatt agcataatat gtatttgttt tttcaaatcg
    31321 ctctgtttca taatcatcat ttccaaaagc tctaattact cttattccag ttaaattttc
    31381 tctcgatata aggtttaatt tatctagtcc tttttgttgt tttgaagata ttgcctgaga
    31441 tacttttgct attattgcta ctccaataat tataaaaggt actgatatag ccaatactat
    31501 agaaagttcc acactggttc taattgtcat tattatactt ataatgaaca taactggagt
    31561 taataaggca gtccttagta gtatattaac aaattgttga atttgaaatg catcattcgt
    31621 tgttcttgta atcattgaag aaattccaaa tttattgtat tcagtatgtg aaaattcttg
    31681 tgatttctca aatatgtcat ttcttatatc tctggttaca cttgttgata ccttagcaga
    31741 acagtaaccc aacaatatac tacctacaac ccctataata gaaataataa caatcactat
    31801 tcccatttgt tttatgtaag ctatattctg atttgcaata ccattgtcaa ttattttagc
    31861 tattatagtt ggaatcccca actcgactaa tgcaaaacta aatatagcca gtatgtttaa
    31921 tactattaat aacttataat tctttaaata acttaaaatt aatttcatat ttttctcctt
    31981 tcttaatttt tgagatagtg taatcatgta ataatactaa atttataaat gcttaatttt
    32041 ataaaaaaag gagaaaagag ttaacgcact ctcttctcca gcatattctt tttaatacac
    32101 cctccgacaa gtcgcttata tgttaacata tttgacaagt aatgtcaatt catatagcca
    32161 aaagtctttt aaatgcttcg tttcataaca ttgtaacaaa ttggcatgta atttattttt
    32221 gttttttact gtattccaat tttacaagtt ctccaatatt actagctttc ttaaaattca
    32281 aattagtctt gtctatacca gacttaaata gtgaaatccc tctccccaat attattggca
    32341 atatatatat ataataatca tcaattaagt tatctttcat aaataatttt actatatcgc
    32401 ctccaccaac tatccaaata tcttttttat ccttctcttt tccaatttgc tcaattaatt
    32461 ttttaggttc taaattaatt tatagtgtga ttattctatg taaacatcac ttttttactc
    32521 attcaataat accctattaa taaatcctca aactaattta aataaacttt gcataaaatt
    32581 aaaaatatat tatataaata atttaaaact acactaactt attgaaaatt ctaattatta
    32641 caaataaata ttgctctctg ttaacgctag ttctataata taattataag ctattaatat
    32701 tataaagccg atattactaa tataataatt ataatactta tagttaattt acttttgttg
    32761 aaaggtggta aataacatga aaatttcaga agtcgctact ccaaattttt tgctagattt
    32821 agaccagtta gaaaagaata tagataaaat tcaacaaatt tgtacaaata ataataaaca
    32881 actttggcct atgcttaaga cacataaaag tacttacata gcgagacttc aaaaaaatgc
    32941 aggtgctagt ggttttctag ttggaacact tgatgaaggt gaagctctga taaaagcagg
    33001 ttttgaagat attatgttgg cttatcctta catgggagaa gtaaatataa atagaattgt
    33061 gactatggca tcaaaaataa atttaatctg tgctacagat aatatagaat gtgctaaggc
    33121 ttatagtgaa gctttttcta aatcaaaaat agagtgcaag ctacttatta ttgtagattg
    33181 tggcttacac cgttttgggg ttgaaccaga aaaagtggtt gaacttgcta ctgaaatttc
    33241 taagctagaa aacatcaaga ttgttggtat aagttcgcat ccaggtcaag tgtatggttg
    33301 tagttctcca gaaggtgttc cagatgtttg tgttcaagaa gattcttcta tggagaaatc
    33361 atacaaagct ctaactgata atggatttaa tatagaaatt gtcgcttctg gtagtactcc
    33421 aacagttgaa tctgaagctg cttctaaaac tataactgct gtaagacctg gaaactatgt
    33481 atactatgat gctatacaga taggtttagg ttgtgctact gaagatatgt gtgctcttac
    33541 tgttgtgtgc actgtaatct caaaaaatag cagtggatac tatttaattg attgtggaag
    33601 taagtgcctt ggacttgata aaggtgcaca tggaaatagt agtattgttg gttatggtag
    33661 ggtatgtgga catccagaac ttactattga ttcactttca gaagaagttg gaaaaattaa
    33721 agtaaatggt gaaactgata taaaaattgg tgatagaata agaattatac ctaatcattc
    33781 ttgttccact gcaaacttga caagtaattt attaggtttt agaggagata caatagaaaa
    33841 agtcatagaa gtagatattc gtgaaaattc aaaacaaatc atcctttaaa aacagattta
    33901 ttctgatatt aacatgaaag tatatttttc ttaaaattat tgttaataac taatgttaat
    33961 gttggataaa taaaaaacat aaattctaga aatataaatt taaaagaaga ggctgtctca
    34021 aaatagagat aagcctctct ttcattgttg aaattatgaa aatatacttg atttcataca
    34081 aaaagagtat ctcatgaact aaaaagttca ctttgagata ctctcttttt tttaattaat
    34141 atacacatta attactatct tagtttatta ctatatatca attactattc attaatcctt
    34201 gtatatatta attcttatat atcatttata gttaggttat aattttatgt tatttacatt
    34261 aatcccataa cagtgagtaa aactcttact attaacatcc ccactattgc atcaaatata
    34321 ggaactgcca acagtaacat tctatactta gtactggcat ttgctacaag cactattctg
    34381 gcataatgac caactagagt acccattaac atacatggca taattaatat ggttgcttgt
    34441 ggtgcagtga ttagaccttg tgcaaataag tttgcagctg tagctgctcc tgctgcctta
    34501 gcaaagaatg ctgctatcaa aactacaaca gattccccag gtagtccaaa aatacccatt
    34561 actggtccaa aaatatttcc taaaatatca actaaaccag ttaattgtaa aaactgcact
    34621 attacataac ccattatcat ggctggtaat atctgttcaa cacctatgta aaaacctttt
    34681 tttgctcccc ccataaatat ctcaacagca gttttcttag gtttactatt tacaattgca
    34741 tttccagtat tttgttgact catactacac agcctcctta gccttattct ttttatttct
    34801 tacacctatg attaatctaa ctagattagc accaagtatt ttacagaata tctctataag
    34861 gattattgga cctaatgcca ataatgctat tggtaaaagt ggagcttgag tatttattgt
    34921 gttcagtata acagctgaac cagcatattg atatgctaca aatatagttc tttcatcatc
    34981 tgttatttcc ccactttcaa ataattcttt cgtcattatt gaggctacat ctgaactagt
    35041 aaatgaagat acaaatgcta ttcctgctat tccaggtata ccaagcagag gtctaagtaa
    35101 tggattaaat atctttgatg ctgctttcat tcctcccata gattcaacta catctataag
    35161 acctacagca aaacagacag ttggaatcaa agtcagagca aataagaaac catcttttgc
    35221 tcccgttcct cctttaccca taaagtctac accatctgca atagtaccaa atgaacctgt
    35281 cagattagca aaatctaatg ctttaaggaa gccttgacta tctttaaaca ctcctgaaaa
    35341 taatactatc aatacaaata aagataaata ccctttccat gttaccttat tatctccagc
    35401 tgttacatcc atataaaatc cccctttata cctcaaattt atctaagttt aaaataactg
    35461 tagaaattaa tttcaccctc tcaaacatag aatctactac tgcatattct cttgatgtgt
    35521 ggttccattc tcctcttaca ccaaatgaac agattgtagg aacgtttgca atagttaaat
    35581 aacttgcatc tgaactacct ccaagtctct tagcatttaa ttctccaaat ccattttcct
    35641 ttgacacttc atttacaaat gtatgaaatc tcataacatc ttctgtagtt tcaaatggca
    35701 tcatttcact tataaaatta acttctgtag aagttccttc tatgtaagtt tctttacata
    35761 tctctctaac ttgttcttta acattctcca tttcttctac tttttcaaat ctaaggtcta
    35821 cttttatact acaatcttct ggaatagaat tttccactct tccaccctta atcacactta
    35881 cacttactgt agttccaaca tctaaattag tcaatttttg tatgcgtagt atcttattag
    35941 ccatttcttc tatagcattt cttccacctt caaaatcatt acctgcgtgt gtttctacac
    36001 cttttacatg tatattacat cctattcttc cttttctacc tacacacaaa ctattatcta
    36061 ctaatccagt ttccatatta aaagcacaaa gaccaccttt tgcttccctc aatataacat
    36121 ctgcacctgt tgaatcctta tgtcctatct cttcatctcc agaaaatact atttttattg
    36181 gtctttcttt gtatcctatt ttatttaatg ctttaataac atataaggaa attattatac
    36241 cacccttcat atctaaaaca cctgggccat atgcttttcc ttctattatt ttaaatggat
    36301 tctctccaaa tgtacctgtt tcaaagacag tatccatgtg acctgaaaaa attattggct
    36361 ttttatctat attagaacca agtgtaccta tcaatgtact accattatct ccaacatcta
    36421 ctaattcgca atctaaacct tctttttcaa attcaagctt taatctctca gctaacttgt
    36481 ttacactttc tttacaatgt gtatagcttt ccatattaac aatctctttc cataatgaaa
    36541 ctatttcttc tctattctca tcaacaaact tagaaatttc atttaaatat gtattcataa
    36601 tcttctcctt tattttcaaa taaaatgtat ttctttccta aaacctaagt ttattttagg
    36661 aaatcttaaa agactagtcc ttaattacaa aatagcacaa ttattcttgc cagtcaacat
    36721 atttttcagt cttttttata ttttctgatt tttctttcaa ttatcctttt gtaaaataaa
    36781 ttgacgcgtt ttatctacta ttataaaatg aggttataaa ttgattgatt agttacaata
    36841 ctctcgaaat tttaaaggag gttttatgaa atataaaatt ggttttttga caacatctta
    36901 ttttatgtca gataagttta aacaagctct taaagaatta aatgatactt gtgaaattac
    36961 atttattgag ctcaaagggg agaatccttt taataattta cctaatatat actatgagca
    37021 agtagataat tttgatggat ttgtatgcag tggtatagtt ccatatagtg aacttataat
    37081 aaatataaaa gacataaaag ttccattaaa ttttttaaag cttgatgaaa gagattttta
    37141 taaatactta ttcaaattat taaatagcca aaaagatatt gactttacaa aatcatttat
    37201 ggatttttta agagaggaca acaattatta tgatatatat tcattaatag actctaataa
    37261 atgtccatat acaattaaag attttaatat ccctcaacct gtatatgact ttaaaaaatt
    37321 aaatgataaa ttattggaaa tacatttaga cttattgcga gataataaga ttaacctttc
    37381 ttttactaga aattacatca ttagttgtga acttaataaa cttggatatg attgtattta
    37441 catggttcca tctacagaat caatcctgaa tacatttaaa tctctggtga atgaaataac
    37501 attacaaaac ttagacaaaa ataaatctgc aacttgtata gttacagtaa atagttcaga
    37561 gtacataaat gaagatttga tatttaaaaa tgatgagata caaaatcaaa tatataacac
    37621 tatattaaat tctctatcaa gacatggatt ttatggagtt caggtcaaaa aaaatgatat
    37681 gaaaatagag atacacacta ctaaagaaat gttaaacaat atgaccaata actatacaga
    37741 tttttttatt tcagaagatt taaaagaaat taaatatagc ttaaatatag gttggggcat
    37801 tggaaataca aatattcatg cagagcaaaa tgctcgtcaa gctaatggta aatctgcttc
    37861 tttgaatgga aactgtactt ttatagtaaa tgatactaat gatacaatag gtcctttata
    37921 ttcaaataaa aattctaata atattgaaga tagctcaata gccaataaag ttgcttcttt
    37981 tatacctcta tctaatacaa atgtatctaa aatcatgtgt atgattaatg atagaaattc
    38041 aaataatgtg tcagcagaaa tattagcaga ctatatgaac ataactctta gaagtgctaa
    38101 tagaatattg agtatcttat ataaagcagg aattgcaact attgtaaata caaaactcga
    38161 taatcaaaga ggaaggccaa aaaaaatata taaagttgat ttcttatctt ttctaaataa
    38221 gatgcagaaa ttaaattctt aatatttaat tttttaataa aagcaatgta ttttctctaa
    38281 ttttaaagaa tcaaaatgtt taaattttat tagaatatac aactttttac tttaaaatac
    38341 ctaaaccttt tatcagtgaa ataaaccata atatatcgta acttattaga aaaacaaaat
    38401 aatttcatat acaaataata aaatagccac tacaatccat aatttgcagt ggctactttt
    38461 tacactatca cttattactt atttttaaaa attaattgta ttttttaaat aatttataca
    38521 cacctattat cagtaaagca ataaatacaa gtatatctat aaaaataatt attgtaacat
    38581 gtctggcaat attgtaaata aaaagtatag agaatatttc tatagacaac gctacaaaac
    38641 acataaaatt cgttaaataa tctgcaatag tatcactata aaaagcatgt atttgtaacc
    38701 atctccatat aaatggacgt aaaaggattc tgaatacaac acaaatgaca gggtaggcat
    38761 aaataaattt tttatctaca taattagcta caccattatt ccattggata ggaatttgag
    38821 gtggcaactt tggaaatact gttatcgcaa tttaaacact acctctctat tctattaatt
    38881 tataactata atatagtctt aaatattttc actctataaa attgtatatt tagtatatct
    38941 taaaatcaaa ctaattatct tttataagtt ttcatacaat aatatctcct ttcaataata
    39001 tatctttttt tatatttaaa actatcttat tttctataaa ataatgtata aacaaggttt
    39061 acagtcaagt atttttatta tttttttgat ttcataaaaa aagcatagca aattatttgc
    39121 tatacttttt tactaaatta tttattctat atcttatatg aacttattgt ttaactacta
    39181 cacaatacta gctttaatca tcatattttt tgcaaacata ctggcttcat atatttcttg
    39241 ttcatctgga tgactttgag attcctcatg gttatttaat tgttggcgaa tatgttcgtt
    39301 gtcaggagaa agttttaaca tctctttata ttttgctttc aatccttctg ctatcttacc
    39361 ttgacatatg aatgaaccta gtatttcatt atcttttggg ataattgatt ctatcttttc
    39421 tattatacta gctccataac ttcctttttt acttgctccc attgttccaa atagtgctat
    39481 ctttttattg tgaatatttt caagcacttg ttttgaattt ttatcacaaa ttcccttgtc
    39541 cacccaatag cctaagaata ctatatcata attttcatag tcaatactat aatcaactaa
    39601 ttcatttaca tctttaatgt ctttttcttc ttgaatttca tcatatatag tataagcaat
    39661 ctttttagta tttccagtta aacttgaata taaaactaaa cttttcatga tgtctcctcc
    39721 tctttatcta aatacttatc taaatcacca aaaatatatt aaccttaaca aattatttat
    39781 ttttataaag atattctaat ctagtataca tccaaactga gagcgtgttt gtaaagcatc
    39841 tgcacacttc ttattacaat aacagcactt tttaatctca tctactcttc catcttttac
    39901 tttctgtaac caattactat ctgctagtaa ttgtcttgac atagaaacca tatctactct
    39961 attatttgaa ataatactct ctataaaatc tgggctagac aattttccaa ccccacatac
    40021 tggaagattt gtgtgtttct ttacctcatc agctaaatat aaaaaacagc cttcatcttt
    40081 aaagtaagga tgattattgg ttggtatagt atcttctaat tttgaatgat ttgcaagtgt
    40141 tacatgaaaa ctgtttacac ctagggattc aaatttttta acaaaatact caacttccga
    40201 aagtaaaact cctgcatttc cataatgagg attttcttgt cttattgcaa atttatagtc
    40261 tattggaatg tccttaactt catctcggat actactaatt atttcgcttg caaatctact
    40321 tctattatca cacgttccac catattcatc atttctatta ttaaatatac ttgatgaaaa
    40381 acttcctaca agcctatcac catgaatttg aatcatatca aaacctgctt tttttgcatt
    40441 caatgctgtt actttaaaca aatttataat atttttaatt tcttctttgg gcatatttgt
    40501 tatgtaatct tttactccat cattcattat tttttttatc tcatcatgtg aagtaattcc
    40561 catattcata gtatctttaa ttaaattagc atcataatct gaacaaaata gttgtgctga
    40621 tacctttgca ccagaattgt gtatttcatc tacaattttc ttgtatttaa tgactccatc
    40681 ttcatccgat aggcttatag ctaccttatg aaaactaggt ctaatagata catctcctag
    40741 agtaatcaga gctactcctg acttagcaat atcagaaaac tttttaattt tttcttccaa
    40801 tttaagaccc atgcttgtag gtgcaaaaga tactctattt tttaattcca aatttccaat
    40861 tttaattggt tttaataaat tacaatacat cctattcttc ctccacagct gtttttatat
    40921 cctttaccac atgtaaattc tttaccagtt ctttatattc tgtatccgag aactcttttt
    40981 ttatgtggtt atcccacttt gaaaatatgt tttttatatc ccctaatact tcctcaccct
    41041 tatctgttac tctcaactga aaagctctac tatcattagg gttttggatt ttttctatgt
    41101 atccatcttg ttctaaccta gatatagttc ttgttgtatg agctttatca acttcaaatt
    41161 ctgtagaaac atcattcaaa gaacaattcc tatttttatt aatataaatt aaatagaaat
    41221 atagaccatt cgtaagttta tatggtttta aacatttttc acaataaagt ttaaagtttt
    41281 tttgcaagtt acaaataata tatgacaaac tttcatactg taaattttta aaatccatct
    41341 taaatttccc ttctataatt ataatatgtt tgactatatc aactatatta tattaaacaa
    41401 ttaatatagt caagaatatt ttattctcta aatctatgtt ttattaattc tttaaaaaac
    41461 tattatataa aataatcatg ataaaattag aaattggaat ttttaatatg cactgtacat
    41521 aaatatattt tatataaaag tttatatttt taaacaagta atttttcgaa aattgtctaa
    41581 attcagtaaa aatatggtaa tatatacata agcaatataa atctataaaa aggagtgtta
    41641 catatgatat ctaataaaat gcaaacttta gttgcaaata gttctgttat aagagctatg
    41701 tttgaagaag gaaagaaact ttctgatatt tatggtgagg aaaatgtttt tgattttagt
    41761 ataggaaatc caagtgttga acctccagag actattaaag cagttataaa tgatatttta
    41821 aatgaagaat ctccaaattt agttcatgga tatatgaaca actcaggata tgaggatgta
    41881 agagatgcta ttgctgaaca cataaataaa aaagatggat taaatcttac aagagaaaat
    41941 ttaattatga cttgtggtgc tgctggtggt ctaaatatta ttttaaaaac tcttttaaat
    42001 cctggtgatg aagttattgc ttttgcaccg tattttggtg agtataaaaa ttatacagaa
    42061 aactatgatg gaaaattaat agaagttcct acaaatatag agacttttga gccagattta
    42121 gatgctctaa aaaatgctat tactccaaaa acaagagctt taataataaa cactccaaat
    42181 aatcctactg gtgtcatata ttctgaagaa ttattaaaaa gtcttggaga attattggat
    42241 tcaaaacaaa aagaatttaa tacaagcata tacctaattt ctgatgagcc atatagagaa
    42301 ataatttatg atggtgccaa agttccttgt gtactaaaat actatagaaa ttcatttata
    42361 ggatactctt atagtaaatc attatctcta cctggtgaac gtataggata tattgttgct
    42421 aatgggcaaa tggatgattt tgatgatgtt atgtcttcat taaatgttgc aaatagaata
    42481 cttggatttg taaatgctcc ttctcttttt caaagggtta ttgcaagaag tttagatgca
    42541 gaagttgatg taaatattta taaaaagaat tttgaccttc tatataatag tttaatcgat
    42601 atgggatatt cttgtgttaa acctaatggt acattctatt tgttcccaaa agctccaatt
    42661 gaagatgata aaaaattctg caatgatgca aaacaattta atttattatt agtaccaggt
    42721 tcttcttttg gttgtccagg tcattttaga gtatcatatt gtgtatctta tgataaagtt
    42781 aaaagttctt taccagcatt tgaaaaatta gccaaattat ataatttaaa ataactaaat
    42841 caaagtaatt caaataatta actaccttag tatagaatac ttacattcta tattaaggta
    42901 gtttataatt ttatgtacta tattttatac ataccatatt attccaatat gcttgaatat
    42961 tcttatctat agtactaata taaattacaa ggaggtgttt gacttgaaaa aaggttatgt
    43021 ttatataata ctgactacct tattttttag ttcaatggaa attagtctaa aaactgtcac
    43081 taatgacttt aatcccttac aaataacttt atcaagattt tttgttggcg gtttagtctt
    43141 actacctttt gctgtaaaaa gattaagagc tcttagtctt tctattacaa aatcagactt
    43201 aaaatacttt gcatttttag gttttatgtg tgtagtagta agtatgtcat tgtatcaact
    43261 tgctgttcta aacacaaagg catctgtagt tgctgttttg ttcagttgta atccagtctt
    43321 tgtaatgctt ttagcttact taattttgaa ggaaaaaata tataggcaca atgtaatttc
    43381 acttatatta gaagttcttg gaattatagt tataataaat ccattgcata caaaactaac
    43441 tcttagtgga atattcttaa cattatcttc tgctattatt ttttcaatgt atactgtatt
    43501 tggtaaaaga aaaaccttaa aatttggtgg aatagttgta acctgcttta gctttatatt
    43561 tggtagtttg gaaatgttga tattggtttt actcactaaa attaatttta tcgcagatat
    43621 attaaataaa aataagcttc atgtatttgc aaatatccct atttttagtg gatatacctt
    43681 acacaatatg cccattatga tttatgtatt cgtatttgtt acaggtgttg gttatgcgct
    43741 ttactttatg gcaatggaag ctacatctac tagtcttaca tctttagtat tcttctttaa
    43801 accagtaata tctccaatac tagcattatt aatacttaaa gaaattatcc ctataaacat
    43861 ggttatagga attttattga tagtaattgg ttcaataatt tctattatac ctacgataat
    43921 tactcaaatg cataataaac acgttgaagc cttgtataag gagtagtaat tgataatcta
    43981 tcatagttat acataagaca aaatttatta gatttaaacg caatataaaa gagatgctat
    44041 tataatagca tctctttatt tatatttatt ttaaatttat taaaactcta tttagctaaa
    44101 ttttgcaaaa agctataagt ttgtggacaa gctgatttta acttactatt tgtatcttga
    44161 tttaaatagt aatatgcaaa tgattctgca aaaaattctt ctggatatac acctaagtag
    44221 tttacattac ctaaagaacg accttcttta gcaaatattt gtttgaattg tgctgattta
    44281 gatatatcat ttaatactat atggtctatt gcatgtgctg tttcatgtaa ttctaaattt
    44341 attgcatcat gccctttacc tttgttacta aatcctattc taagagctac tgtacttcca
    44401 cctaaacctg gaacatcatc ccaagttttt ccagtacctt cccatccctt aggaactaca
    44461 ccttttaaat aagcatattc tttttcatct gttaactttc cacttaataa ttttattttt
    44521 aagttatttt gctttaatgc atttaaatac tttccatcta tattagctaa tctattcacc
    44581 atagcattag cttcgttttt atcgtaattt ccagttggaa aaactactat ttgactaagt
    44641 gtgtctttat tttgttgtat agtagtacta tctgcatgtg cacttactgg aactgaactt
    44701 attaagaata ttgatattat agctattaat aattttttac ttggtctcat attattccct
    44761 cctttgagtt aggccgggag taataaattt caaaataaaa aagataccca agagtatctt
    44821 tgtatataca aaaagaaatt tttactcttt tcggcaactg gctggcatgg tttactaaac
    44881 tttagcccct atagctttgc gtgactaggt ttccctagtt ttgcctcatt taattttata
    44941 tctatattat agcttatatc tttttaattg tctatatccc tttggaactt ttttctaaaa
    45001 agttattatt tttttacata aatcttcaaa aaaaaatatc ttctaacaat attttcatta
    45061 ttaaatattg ttttagaaga tattttttaa tataacttat attttttata atgttagggt
    45121 ctaatttgta tttttatttc ttcttaatac gataagtcct acaatagctc ctataactaa
    45181 aagtatttct ccaataattg tagtactatc ccctgttttt ggtggtactg gtggatttac
    45241 caaagtatca tctttaactt tattattttt ttcttctgac actgatggct ttactacttc
    45301 tggtattgga ataatctgtt taacaggagt ttctatcatc tcttctgatg gtggtactgg
    45361 aggattcaat acctctggta ttggcggatt tattatatct tctgatggtg gtactggtgg
    45421 atttataact atagtatcct ctgtatcaga tgaacttgat ggtttccttg gtttatctgt
    45481 gcttggtggt actggtggat ttactattgg ttcatctgta tttggtggtg ctggtggatt
    45541 tactggtgga ttttcttgtc ttatgttttc tatatttcca atatccacta ttctaccaat
    45601 atctttatta ccaatttcaa ccttaatttt atccttcagt ttttcatatc cacttggagc
    45661 cattatctcc actaaataat atgttcctgg tttttttaca ctagattgaa ttataccatc
    45721 ttcatcacta actaaatcct taactactat atttccaaat gcatcttcta aattgaactt
    45781 agcacctgaa agtacatttt tatctaaagc atccactttt ttagcttcaa aagcataacc
    45841 ttgcttagta gtctctactc ctggaggact tgaaccatta atctgagcca cattttgtat
    45901 agtctcccca acttttacat ttgtgaagtc tgcatcaaat gtaacccaac tttgcacagg
    45961 ttccccttct tttatctgtt taaattcgta tttatttact aatcttattg tattttttcc
    46021 atctccagct tcttttttaa gttcaagatt atcagaatat tttatattag atatttctag
    46081 agctgagttt acttcatcta aaagatttac ttgtcctgca tcataaaccc cataagttga
    46141 catattgatt ttgtatttaa caatctggtt atcactacta tttaaaactt ttttatcaac
    46201 ttcttttttt gcgcttatta atccagaatt tttcttaaag tttatctcat catttttatc
    46261 aatttcacta ttatttgcat caagaacagc tctatttata tagctatctt caatactaat
    46321 tacttttaat gtataagcta taaaaaactt tgattccact tcttctttac tgagattaat
    46381 tgtaaatcca gttataactt tatctacttg cccactttca tttctttttt cttctacttt
    46441 atatgaaata ttattggcaa ttttttcttt actccaagga gtccagctcc cattcattgg
    46501 aatttctaca actctaaaat catgcccagc ttctcctgaa gtagttaatc tcatgccttc
    46561 tggtatatta tctgttataa caacattact tattggtgat ttatcatcat ttattgaaat
    46621 ctgatagttt attacttgac caacttgagt aatatttgtt gctcctgaat gtcctttagt
    46681 aagaagataa tcatctcctc tatcaaatat acttacagta gcatcatctt cttgtatctt
    46741 cttaccatca gattcaatcc tagctacatt cttatattta ttaccatgtt ttgcattttt
    46801 gtcactgatt ctagccttat acttaacagt atacgattta tctatatttc caaaattaac
    46861 tgaaatagaa tttttactct gttcaatatt aaaatcacta acttcttttc catcacttgt
    46921 tactacactt acagaaccat ttatcaatgt caatccttca ggaagctcat catacaaaat
    46981 aatatctttt aactcttcct gcttttcatt tacttgtata ctgtaattta tatctttatt
    47041 tttaactggc ataaatacag tagttgattt ttttccttca acaagctttt taagtgttcc
    47101 tttagcatct ggaacatccg ttttatctcc aggttttatt tctacatcta tatctccact
    47161 tccactttct atttttccag tagtttcaat atgtattttt gcattagtat cttcatcaac
    47221 ctttttaaca tatgcttcca aacctatttt accttgcatt acactttggc cattaggtaa
    47281 ttctctaaat gtaagtgtat actctccatt actttctgtt ttatcaaagc attcacttgt
    47341 ataatctaaa ttaactttat tgaatacatc tggcacctta aaagttattg aatctcctgc
    47401 ttgtattcct tttgatgttg gagtataagt taaattaaat gatatttttt tcattgattc
    47461 cgtttctatt gtattgttat taatttttac aacaaatcca tagtcttcat tttcttcatt
    47521 aagttcttct tctaaaactt tcaataaatt ttcatcttct aatagattat cttcctctgg
    47581 agttttttct gtatttttat tgtctagtgg tttttcatct tctaaagctt gttctgactt
    47641 tttattatct gttgacttat cttcttctgg tatctgctct ggctttttat tatctattgg
    47701 cttttctcct tctggagttt gctctggctt tttattatct gttgacttat cttcttctgg
    47761 ggtctgttct ggttttttat tatctgttgg tttttcttcc tctggggtct gttctggttt
    47821 tttattatct gttgccttat ctttctctgg agtctgttct ggctttttat tgtcgctttc
    47881 cttctcctct ccagttgatg aattagttga accactttga atctgactat tctctcctaa
    47941 ttctgaagca taagatacag ttggatatat tgtagacact accatactta aaatcataat
    48001 taaactaatt aataatgcct ttctatttca tttcttcatg taaatctcac ccctttaggt
    48061 tacctataat ttataatcta atcttccatt aatatcgtat ataaagtaat ttttactaaa
    48121 aaattataca aaaaaagcta tgaaaataaa taaatttata ttcatagccg gttgcaccac
    48181 tgactcagta tatccataag gtgcccaata atagaatata cttcaacatc tctataatat
    48241 ttcataaaaa caattaaaat tgctttattt atattaaaaa tacaattata tacttctatt
    48301 atattatgcc tctatactat tgtctatcct ttttacattt tttaccttat gatgagatta
    48361 attaataatt aaataaaatc cttatctaca acaattacac aattatattc aggatttatc
    48421 tccttaacta attttgttat atcttctttt aagtcatctt ctgacatgtt tttggaaaat
    48481 tcggaaggat taactactac atcaaatatt aaattcttct tgcttccttt tccaactatt
    48541 ctaaaatcat gcatagattt tacaagacta tttttcttaa gtatttcttc aagttctttt
    48601 ttggctgaca taacttcttt atcttcaaga catattgggt ccatgtgaat tactagatat
    48661 atatctaatt tttcagatat ttctctctct gcagtatcta taatttcatg tatttccatt
    48721 atatctatat tggatggaat ttctgcatgt atagatgcaa tacatctacc aactccatag
    48781 ttatgaataa ttaaatcatg tgtacctatt atatatttat aagataacaa tagctctata
    48841 atagaattta ccatttcttc atccggtgct tctcctaaaa gaggatttat agtatctttt
    48901 acaagagaga aaccagcata aagtatcact aatgatacta cgataccaac atatccatct
    48961 atgggaaaat tagtaaatct agctacaata aatgatataa ctacacaact tgaagtaaat
    49021 acatctccta aagcatcaag tgaaactgct tttaaggctg aagaatcaat tttatttccc
    49081 ataaatttat taaaacgact caaccagatt ttaatcatta tagatgcaat taaaagtata
    49141 agtggtatta cttcaaattt tacaggaatt ggatttacta tcctttctat agacgacttt
    49201 acaaattgaa gtccaaccaa catcaccata aatgctacta ttaatgctga taaatactct
    49261 attcttccat gaccaaaagg gtgttcttta tcagctggct tacttgctaa tttaaaacct
    49321 atcatagtta ttgctgaaga tgccatatca gaaagattat taaatgcatc agccattata
    49381 gctatactag atgtgagcat tcctatgaat acctttatca caaataaaag taaattggat
    49441 aatataccta ctacaccagc tacataacca tacttatttc taacatctgt attttgaacg
    49501 ttttcgctat ctctgataaa tgttttgact aagattttgg aaaacatgaa acttacctcc
    49561 ctgcccttta ttttattaac aaattttata atctatatct ttatttatga taacataatt
    49621 tatatataaa attcttaaaa atcactctac ttcagtaaaa tattattcta tatatctatt
    49681 tagatacgaa ttttatattt agtaaagttt ttatggctta gtgtctgttt aatagattct
    49741 atataagttt ttacaaagat tatttattat gataatatca tttttcccaa gtattactta
    49801 gaatatgatt tttttgtttt gtctgtacat attttaaatt tatactatat ttatctatat
    49861 tttataacct tatgatacac tataactata agattttaaa tggaaaggaa tgaaataaat
    49921 catgtttttt atcagtgata tttacacaaa atcacctatt aaatttgata ctcctttgca
    49981 aaaagaggca tacaaaatat tacaaaaatt agatattgac tttgaatgtg ttgacacaga
    50041 tgaagcaatt acaatggaag attgtgttca gattaataaa aaattaaata tgaaaatggt
    50101 aatataaaac aacattaaac aaacaaaaac cgcaaagtta caatatatag tactttgcgg
    50161 tttcataaga attaattttt actattaaag ttcatagttc tactattttt cattgttcta
    50221 agaattagct ttacaaattc atttgacaat aggatagtgg atgcaaatag tattatcttt
    50281 atccacatat caaagtccaa agaaacagaa ttaaagaaac tctggaacac ttgtgtaaat
    50341 attatttgaa ttatccctgt aactactatt atttgcaatg ccagtttatt tttaaagaaa
    50401 tttggtattg tactatttaa accaaactct ctacaattta atgcattaaa aagggcactg
    50461 aatgcaaata aagaaaatat aacagtacct tgttcttctg atgtagctcc caatatatta
    50521 aaagctgatt gagtaaatac aattgtaatt ataagaatag catttataat aatatttaca
    50581 aacatagacc tagctattat tccagaatgt ctatttattg gttttctttt caatacataa
    50641 tctctaacag gttctaatcc taatgctagg gctggaggac catccattat tatatttacc
    50701 cataataatt gtattgtagt aaatggcata tccttaccag taagttgaga tattatagca
    50761 attataaatg ctactatatt tacagtaagc tgaaactgta taaatctttg aaagttctca
    50821 tatatacctc ttccccattt tattccctct actatagtac taaagctatc atcagtcaat
    50881 attatatctg ctgcattttt agatacttct gttcctgaaa tacccattgc aattccaaca
    50941 tctgcttgac taagtgctgg ggcatcattt ataccatcac ctgttacagc tacaacttcg
    51001 ccactttttt gaagtgctga aactattctc atttttgtat ctggtttact tcttgcaaca
    51061 atagatattc ctttgatttc ttctctcaat tctttatctg tcaatacatc tatatatgtt
    51121 gcttcaactg cctttttccc atcatttaat aatcctaatt catttccaat agctgttgct
    51181 gtatttatat tatctcctgt aagcattttt acatctacgc ctgcattaaa tgctttatca
    51241 atggaatctt tgaccccttc tctcaatggg tccactattc ctacaaatcc actaaaaact
    51301 aaattatctt ccttcatata acttcttgaa tttcctatta aattcaattc accttctgaa
    51361 gtcattgcaa cttctgtttt agaattactc atttttttat aagcaaatcc taatgttctc
    51421 atagatttaa tttgtaactt cttaatctca tctaaaatac ttttttctac ttttggagtt
    51481 attggaacaa tattttttcc ttgttgtaca taagaacatt tttttaataa tacttctgga
    51541 gcaccttttg aaagtaatat atctgaatcc tcttgacgaa ttaatgttga catcttcttt
    51601 tcttctgaac taaatggtat ttgtgatatc aaatacgttt gttttctcat ttcattatag
    51661 ttcttatcat tatgatataa aagtaatgca cactctgttg cgcttcctat atatttaaat
    51721 gaattatctt ctttttctat atctgcagtt gaatttacta tacagttttg ttcaaaatag
    51781 ctattacttt gatactctcc tccacttata tatttaccat caacatatgc tacctctacc
    51841 atcattttgt tttgtgttaa agtccctgtt ttatcggaac atattacaga aacagaacct
    51901 atagtttcac aggcttcttt ctttgttact aatgcattta tctttgccat cttttgcatt
    51961 gttatagcta aggtaatatt tatcatagtt ggcaaacctt ctggaacagt tgcaactatt
    52021 aatgcaatac aaaccatata tgcattttta gcaggttcta atgattgtaa gaaagataat
    52081 acactgcttg tatctaaaat taacatacct tttctctgca tctgtataat cataaacata
    52141 cacaataaag tagctattat gcctgatatt cccgctattt tagcacccaa cttccctaat
    52201 ttaatttgaa gtggagtttg ctggtcttca tttgataaat tctgtgctat cttacccatc
    52261 tctgtcttat caccagtatg agtgacaacc attatgcccc taccatatgc tacaagagtc
    52321 cctccaaata ccatattgac ttgctttgca ggtattgcat cctgttcgat tatttctgtt
    52381 ttagaataaa ctacttccat atctaataca gcatcagcat tcttagctac atcatcagat
    52441 tctcctgtta gcatatcttc tctaagtttc aaatttatag actgtataag tcttccatct
    52501 gctggtatca tatccccagt ttctatatat acaatatctc ctggtactaa atcatttttt
    52561 gatattttaa ttatcttccc atttctaagc acctttactt ctatattttc tgttaatttt
    52621 gacagggcat gagctgcttt tttagatttt ccttcagtta ttatgcctat agaaattcca
    52681 ataaaaatag cccctaaaat acctaatgcg tcatgtaatt ctcccacaaa agaacttatt
    52741 actgctgctc ctatgagaat taatatcata ggttctgtca aactttctcc caactcgtcc
    52801 caaaatgttc taccttcttt tatagtaaat tcatttaatc catatctaag cttcctttct
    52861 tctacctcat tatcatcaag tccaatttct ggatttgttt ttaagtattt taatacttct
    52921 ttggtaggtt tattataata cctcataact ttatccccct tgttaattat ctataaggaa
    52981 ttatatgctt atgatagctt gtatattact tttcaaaaaa aataaggtgt tgattaatca
    53041 acaccttata gtggttatat attattaaat tttatgttac aggctttata aattgtgagc
    53101 tatacaaatc aaaatattta atcttcaaaa tacccttctg gatataatgg aaacttagat
    53161 ataagttctt gtgcctctgc tttacattca tctaatactt ctttattatc aatattttct
    53221 gctaccttat tcattatccc tgctatctgt ataacttctt tttctttcag acctctttga
    53281 gatattgatg taagacctat acgaacacca ctagttacaa atggtgattg tgggtcgtca
    53341 ggtataacat ttttattaac tgttattcct acatattcaa gagctttttc aaattgtttt
    53401 cctgtaagat tcttatttct taagtcaacc attactatat gattatcagt acctccactt
    53461 acaatactaa aaccatgtga aatcagttca gaagctagag tctgagcatt tactacaact
    53521 tgctccatta tctttttaaa tttatctgta cttaaatata atagtgaaaa ggcttttgct
    53581 gcaactgtat taagatgtat agaccctaat gttcctggaa aaacaccttt atcgagtttc
    53641 tttgcatgtt ctgctttaca aagtacaata ccacttcttg gtccacagaa agtctttgtc
    53701 gtagatgaag aaacaaaatc tgcataaggt acaggactag gtattacttt cgctgcgact
    53761 aatcctgcaa catgtgccat atctaccata aagtaagctc ctacttcttt tgcaaccttt
    53821 gatattcttt cataatctat taatcttgga tatgaacttg cccctgcaat tataagtttt
    53881 ggtctacatt cttttgcctt tgcttcaaga gcatcataat ctatacgtcc agtatttggg
    53941 tctaccccat aaaattcata tttataaatg tcatgtaaaa aattaactgc gctaccatgt
    54001 gtcaagtgtc caccttggtc aagacgcata cttaaaacag tgtcatttgg ttttaatatt
    54061 gatgaatata cacaatagtt agctgtagaa cctgaatacg gttgtacgtt tacatgttct
    54121 gctccaaata cttcttttgc acgttttatt gctagggttt caagtttatc tgcttcttca
    54181 gaacctgctt gaaaacgagc ccctggatag ccttcttctg ttttatttgt aaatacacat
    54241 ccacttaatt caagtacttc tgttggtgct gtactttcag aagctatcat ctcaatattg
    54301 tgttcttgtc taaccaactc atcagctaca atcttgtata actctgggtc tgaaattttt
    54361 gttgttttta acataataat cctcctctta attaaagaat atattttatt agtttaatct
    54421 tcattgataa atttattata atggtctata aaacgtaaga tattcctcca ccaggtccta
    54481 atggtatgcc aatacccatg aatagtaaca atattattat ttctattaat gtaaatacca
    54541 ctgagtatgg aatcatattc gatatgacag tacctatacc tatatcttta tcatatcttc
    54601 tggcaaaggc caatataact ggaaaatacg gaaaaagtgg acttattgga tttgttgaag
    54661 catctccaat acgataagct atttgagtta atgctggatt aaagtctagt agcataaaca
    54721 tgggaacaaa tataggtgct aaaatcgccc attttgcaga agcacttcct acaaataaat
    54781 tgataaatcc agatagcaat ataaatccta ttatcaatcc atagctaggt attcccgact
    54841 ctgctagtaa ttttgctcct gttattgata aaattgttcc taagttacta agattaaata
    54901 aattaataaa ctgggatgct ataaatgcta ggactatata tccacccata tcactcatac
    54961 tactacccat catagatact aaatctttgt cactttttat cttcttactt acttttccat
    55021 acactaatcc tggagttaaa aatataatag tgattatagg aactatacct ttcattaaag
    55081 gtgcattact agatagtata gaaccagtct ctggatcttt cataaatgca ttgtcaccta
    55141 tacataaggc aactatcact actactacaa ctaacaatga taataaagcg tattttatac
    55201 ccttattttc aagttcactc aattcctgta tatccttatc atttgttgaa tcattatatt
    55261 ttgtaaaacg aggagctata aatttttcag ttacaaatgc tcctgcagaa gttaaaacta
    55321 tcgctgatat aaaagcaaaa taaagattca ttgctggatt gccttggtaa gatgggtcca
    55381 tcatttgagc tgctggtatt gtaaatccag ctaacaatac atctgtagta ctaagcataa
    55441 catttgctgc aaatccccct gcaacacctg caaaagctgc aaacatacct acaagaggat
    55501 gtcttccaat tcctaaaaac acaagtgctg caagtggtgg taatattata aatcctacat
    55561 ctgctgctgt atgtgataac atacctgcaa atacgattgc tacagttaca agtttttgtg
    55621 gaactttact tatacccttt ttcattaaca cttccataaa tccagatttc tcagcaacac
    55681 ctgctccaag cattgtaacc agtactaatc ctaaaggagc aaatgactgg aagtttgtaa
    55741 ctatgctacc taaatatgat tgaatctgct ctttctctag tagatttact acctttacaa
    55801 cttcttttgt agaaggatgt atttcttcta ctcctaaatt agatataact gctgacaata
    55861 ttacaacaat tatacatagt aataaaaata tggttactgg gtctggaagt ttatttcctg
    55921 ctctctctac aacatttagt gccctcatca ataatccact atctttgttt ttttcctgtg
    55981 aattaatttt cctcaaacta ataccccctc ataaacttta tctccagaat gctttatctt
    56041 aaattttatt ttttaattta tccatataat ttataacaga ctgacatagt acatttgtac
    56101 ctaccaatat agaattttta tcagctttaa atttaggatt atgccactga tatatacaat
    56161 cttgttcttt gttgcctacc cctaaccagt aaaaaaatcc tggggctttt tccatgaata
    56221 tagaaaaatc ttctcctcct gtagaaggta ttggatcaac tatagcatct tctgaataca
    56281 aatcacacac agacttacaa gctattgcgt acatctcttt actatttata acagctggta
    56341 aatcaaataa ataatctagc tttgcagttg cttgatatcc acgagctatc tcacaaacta
    56401 tattttctaa attttctgat atttttttcg tacttcatta ctaaagcttc tacatgtgcc
    56461 tgtcatatct accttttctg aaattacatt atttgcagtc cctccattta tagtacctat
    56521 tgatataaca gctgattcta atggacttat gtttctgctt actatggttt gaatacccat
    56581 tataattgca cttgatgcta ctatagggtc tattgttctg tttggtatac ctccgtgacc
    56641 tccaaatcca tttacttcta tcttaatagt gtctactgct gccattaacc cacctaactt
    56701 aacacctatt tttccacaag gtatatctgg atgattatga agtccaaata tagcatcaac
    56761 ttttggattt tccattactc ctcgttccac tagcatcttc gcacctttat tgacttcttc
    56821 ggctggttga aatataaact ttacatttcc atgaagacta tctctaatat gagacaatac
    56881 atatgcacat cctacaaggc aagacgtgtg tatatcatgc ccacatgcat gcattatacc
    56941 atcatatctg gatttatact taatatcaac ctcttcatat attggcaatg catcaatatc
    57001 tcctcttagt gctactgtgg gaccatcata cttccctttt aataatccaa caactcctgt
    57061 ttccattcct aaatctaata tttctatgtc taaacttact aataaatctt ttatagcttt
    57121 tgtagtccta aattctttaa aacttaattc ggggtgcata tgaatatctg taaaaaaatc
    57181 taaaatatct tctttatact tttctgagat taaaataagt tcatgcatac taacacctct
    57241 ccaaaatttt atttttttat tttttataat ttaactac
//
LOCUS       DAEPXW010000011        56934 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.011, whole genome shotgun sequence.
ACCESSION   DAEPXW010000011 DAEPXW010000000
VERSION     DAEPXW010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56934
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.011"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..166
                     /locus_tag="KRM55_000673"
     rRNA            <1..166
                     /locus_tag="KRM55_000673"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            294..410
                     /gene="rrf"
                     /locus_tag="KRM55_000674"
     rRNA            294..410
                     /gene="rrf"
                     /locus_tag="KRM55_000674"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            418..492
                     /locus_tag="KRM55_000675"
     tRNA            418..492
                     /locus_tag="KRM55_000675"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Asn,seq:gtt)
     gene            498..583
                     /locus_tag="KRM55_000676"
     tRNA            498..583
                     /locus_tag="KRM55_000676"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:532..534,aa:Leu,seq:taa)
     gene            599..674
                     /locus_tag="KRM55_000677"
     tRNA            599..674
                     /locus_tag="KRM55_000677"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:632..634,aa:Met,seq:cat)
     gene            682..756
                     /locus_tag="KRM55_000678"
     tRNA            682..756
                     /locus_tag="KRM55_000678"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:715..717,aa:Glu,seq:ttc)
     gene            771..844
                     /locus_tag="KRM55_000679"
     tRNA            771..844
                     /locus_tag="KRM55_000679"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:803..805,aa:Gly,seq:tcc)
     gene            850..925
                     /locus_tag="KRM55_000680"
     tRNA            850..925
                     /locus_tag="KRM55_000680"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:883..885,aa:Val,seq:tac)
     gene            931..1007
                     /locus_tag="KRM55_000681"
     tRNA            931..1007
                     /locus_tag="KRM55_000681"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:965..967,aa:Asp,seq:gtc)
     gene            1018..1092
                     /locus_tag="KRM55_000682"
     tRNA            1018..1092
                     /locus_tag="KRM55_000682"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1050..1052,aa:Gly,seq:gcc)
     gene            1102..1175
                     /locus_tag="KRM55_000683"
     tRNA            1102..1175
                     /locus_tag="KRM55_000683"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1136..1138,aa:Arg,seq:tct)
     gene            2159..2998
                     /locus_tag="KRM55_000684"
     CDS             2159..2998
                     /locus_tag="KRM55_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBH1592941.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            2995..4176
                     /locus_tag="KRM55_000685"
     CDS             2995..4176
                     /locus_tag="KRM55_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592942.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4480..5382
                     /gene="ptb"
                     /locus_tag="KRM55_000686"
     CDS             4480..5382
                     /gene="ptb"
                     /locus_tag="KRM55_000686"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBH1592943.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            5404..6483
                     /gene="buk"
                     /locus_tag="KRM55_000687"
     CDS             5404..6483
                     /gene="buk"
                     /locus_tag="KRM55_000687"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH1592944.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6473..7150
                     /locus_tag="KRM55_000688"
     CDS             6473..7150
                     /locus_tag="KRM55_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1592945.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            7193..7408
                     /locus_tag="KRM55_000689"
     CDS             7193..7408
                     /locus_tag="KRM55_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1592946.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7437..8516
                     /locus_tag="KRM55_000690"
     CDS             7437..8516
                     /locus_tag="KRM55_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH1592947.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8516..9268
                     /locus_tag="KRM55_000691"
     CDS             8516..9268
                     /locus_tag="KRM55_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH1592948.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            9269..9826
                     /locus_tag="KRM55_000692"
     CDS             9269..9826
                     /locus_tag="KRM55_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH1592949.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            9996..11342
                     /locus_tag="KRM55_000693"
     CDS             9996..11342
                     /locus_tag="KRM55_000693"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBH1592950.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11609..13441
                     /gene="glmS"
                     /locus_tag="KRM55_000694"
     CDS             11609..13441
                     /gene="glmS"
                     /locus_tag="KRM55_000694"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBH1592951.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            13893..15188
                     /locus_tag="KRM55_000695"
     CDS             13893..15188
                     /locus_tag="KRM55_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBH1592952.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYLDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            15665..16402
                     /locus_tag="KRM55_000696"
     CDS             15665..16402
                     /locus_tag="KRM55_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBH1592953.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            16423..17676
                     /gene="murA"
                     /locus_tag="KRM55_000697"
     CDS             16423..17676
                     /gene="murA"
                     /locus_tag="KRM55_000697"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBH1592954.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            17763..18827
                     /gene="spoIID"
                     /locus_tag="KRM55_000698"
     CDS             17763..18827
                     /gene="spoIID"
                     /locus_tag="KRM55_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBH1592955.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            18893..19561
                     /locus_tag="KRM55_000699"
     CDS             18893..19561
                     /locus_tag="KRM55_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBH1592956.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            19659..19919
                     /gene="spoIIID"
                     /locus_tag="KRM55_000700"
     CDS             19659..19919
                     /gene="spoIIID"
                     /locus_tag="KRM55_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBH1592957.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            20116..21135
                     /locus_tag="KRM55_000701"
     CDS             20116..21135
                     /locus_tag="KRM55_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH1592958.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDFVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            21151..21579
                     /gene="fabZ"
                     /locus_tag="KRM55_000702"
     CDS             21151..21579
                     /gene="fabZ"
                     /locus_tag="KRM55_000702"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBH1592959.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(21690..22199)
                     /gene="yyaC"
                     /locus_tag="KRM55_000703"
     CDS             complement(21690..22199)
                     /gene="yyaC"
                     /locus_tag="KRM55_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBH1592960.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      22388..22491
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            22628..23821
                     /locus_tag="KRM55_000704"
     CDS             22628..23821
                     /locus_tag="KRM55_000704"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBH1592961.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            24138..25235
                     /locus_tag="KRM55_000705"
     CDS             24138..25235
                     /locus_tag="KRM55_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592962.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPVIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            25499..27718
                     /locus_tag="KRM55_000706"
     CDS             25499..27718
                     /locus_tag="KRM55_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBH1592963.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEILKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            27721..28503
                     /locus_tag="KRM55_000707"
     CDS             27721..28503
                     /locus_tag="KRM55_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBH1592964.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            28835..30748
                     /locus_tag="KRM55_000708"
     CDS             28835..30748
                     /locus_tag="KRM55_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1592965.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIQGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            30889..31197
                     /locus_tag="KRM55_000709"
     CDS             30889..31197
                     /locus_tag="KRM55_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1592966.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            31221..31547
                     /locus_tag="KRM55_000710"
     CDS             31221..31547
                     /locus_tag="KRM55_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1592967.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            31586..32920
                     /gene="celB"
                     /locus_tag="KRM55_000711"
     CDS             31586..32920
                     /gene="celB"
                     /locus_tag="KRM55_000711"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBH1592968.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            32931..33449
                     /locus_tag="KRM55_000712"
     CDS             32931..33449
                     /locus_tag="KRM55_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBH1592969.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLTDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            33545..34504
                     /locus_tag="KRM55_000713"
     CDS             33545..34504
                     /locus_tag="KRM55_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBH1592970.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCVATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            34553..35605
                     /locus_tag="KRM55_000714"
     CDS             34553..35605
                     /locus_tag="KRM55_000714"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBH1592971.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            35608..36282
                     /locus_tag="KRM55_000715"
     CDS             35608..36282
                     /locus_tag="KRM55_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBH1592972.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVHNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            36835..37386
                     /gene="raiA"
                     /locus_tag="KRM55_000716"
     CDS             36835..37386
                     /gene="raiA"
                     /locus_tag="KRM55_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH1592973.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            37518..40193
                     /gene="secA"
                     /locus_tag="KRM55_000717"
     CDS             37518..40193
                     /gene="secA"
                     /locus_tag="KRM55_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH1592974.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            40208..41315
                     /gene="prfB"
                     /locus_tag="KRM55_000718"
     CDS             join(40208..40282,40284..41315)
                     /gene="prfB"
                     /locus_tag="KRM55_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBH1592975.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            41459..43600
                     /locus_tag="KRM55_000719"
     CDS             41459..43600
                     /locus_tag="KRM55_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBH1592976.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            43748..44914
                     /locus_tag="KRM55_000720"
     CDS             43748..44914
                     /locus_tag="KRM55_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1592977.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      44974..45091
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            45216..45821
                     /locus_tag="KRM55_000721"
     CDS             45216..45821
                     /locus_tag="KRM55_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1592978.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            46150..47190
                     /locus_tag="KRM55_000722"
     CDS             46150..47190
                     /locus_tag="KRM55_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH1592979.1"
                     /translation="MNLSKKIKKLFLDDKGYYFNSNWKDIHIGIYNTKLGDSLKYITN
                     EYIENLERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            47329..47781
                     /gene="tsaE"
                     /locus_tag="KRM55_000723"
     CDS             47329..47781
                     /gene="tsaE"
                     /locus_tag="KRM55_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBH1592980.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            47781..48497
                     /gene="tsaB"
                     /locus_tag="KRM55_000724"
     CDS             47781..48497
                     /gene="tsaB"
                     /locus_tag="KRM55_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBH1592981.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVDFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPTNNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            48487..48963
                     /gene="rimI"
                     /locus_tag="KRM55_000725"
     CDS             48487..48963
                     /gene="rimI"
                     /locus_tag="KRM55_000725"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBH1592982.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            48969..49985
                     /gene="tsaD"
                     /locus_tag="KRM55_000726"
     CDS             48969..49985
                     /gene="tsaD"
                     /locus_tag="KRM55_000726"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBH1592983.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDNANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            50282..52990
                     /gene="hpdB"
                     /locus_tag="KRM55_000727"
     CDS             50282..52990
                     /gene="hpdB"
                     /locus_tag="KRM55_000727"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBH1592984.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            52994..53251
                     /gene="hpdC"
                     /locus_tag="KRM55_000728"
     CDS             52994..53251
                     /gene="hpdC"
                     /locus_tag="KRM55_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBH1592985.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            53244..54194
                     /gene="hpdA"
                     /locus_tag="KRM55_000729"
     CDS             53244..54194
                     /gene="hpdA"
                     /locus_tag="KRM55_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBH1592986.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSVENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            54510..55472
                     /locus_tag="KRM55_000730"
     CDS             54510..55472
                     /locus_tag="KRM55_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1592987.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(55571..56551)
                     /locus_tag="KRM55_000731"
     CDS             complement(55571..56551)
                     /locus_tag="KRM55_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1592988.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        22785 a         6158 c        10763 g        17228 t
ORIGIN      
        1 cggaatggat aagcgctgaa agcatctaag cgcgaagcca acttcaagat aagatttccc
       61 accgcaaggg taagacccca gaaagactat ctggttgata ggtcgaaggt gtaagtgcag
      121 caatgtattt agcttatcga tactaatagg tcgaggactt gaccaatatt tatttgatgt
      181 tcattcatta agatatatgt gtagttttta gagtgctaac tctaaagaaa ctagtattgc
      241 taggttctat aaacttatta aaaacttaat agaaatatta agcataaaga ttatgtggtt
      301 acaatagcag agaggataca cctgttccca ttccgaacac agaagttaag ctctctagcg
      361 ctgatggtac ttggtgggaa actgcctggg agagtaggac gtagccacgt taaatgttcc
      421 aaggtagctc aacggtggag caaccggctg ttaaccggta ggctgtgggt tcgagcccca
      481 cccttggagc caaaaaagcc gaagtggcgg aactggcaga cgcacaggac ttaaaatcct
      541 gcgggactta cctctcgtac cggttcgatt ccggtcttcg gcacttataa aacaatatcg
      601 cggggtggag cagttggcag ctcgtcgggc tcataacccg aaggtcgtag gttcaagtcc
      661 tgcctccgca accattaaaa cggctcgttg gtcaagaggt taagacaccg ccctttcacg
      721 gcggtaacag gggttcaatt cccctacgag tcaccaattc aattaaatat gcgggtgtag
      781 ctcaatggta gagttctggc cttccaagcc agctgtgagg gttcgatccc cttcacccgc
      841 tccaaaaatg ggaccatagc tcagctggga gagcacctgc cttacaagca gggggtcaca
      901 ggttcgagcc ctgttggtcc caccattcgc ggcctggtag ttcagttggt tagaatgcca
      961 gcctgtcacg ctggaggtcg agggttcgag ccccttccag gtcgccaaat taaataagcg
     1021 ggaatagttc agtggtagag cgcaaccttg ccaaggttga agtcgcgagt tcgaatctcg
     1081 tttcccgctc cataataact tgggtgcata gctcagctgg atagagcaac gcccttctaa
     1141 ggcgtgtgtc cggggttcga atccctgtgc gctcattaag aaaagtttac tataaattat
     1201 agtaaacttt tatattgttt aaaaagacac aggaaacatg tatattacct gtgtcttttt
     1261 atttataaac tttaaactat gtaaaaatta cagtatattc taatagagtt acagtatatt
     1321 cattaatatt gtaaacatac ggagggtaat gtataatagt ctacaagatg tttatgaagg
     1381 catcagttaa atataataaa tataactaat tagtaagagt tatatacatt atattgtata
     1441 ctttatggta tttatatatt gaaataactt atgaagttat ttataaagag attcatgagc
     1501 atatttttgt ctaaacaata agtataagaa attataaaaa attagagact atagtgaatt
     1561 tacaatttaa tgtaatattt ataagttata ctaaataaat tattatactg tgaaatggat
     1621 atataacttt aggtattgtg tattattttc actgtaggag attatatcta gttatacata
     1681 ataagtttta atgatagttt atagtaagat attaaaataa atttatctaa tctagatatg
     1741 aaataagtta ttactttaat ataaaaatga atctaatgga ataatattga tgataagtaa
     1801 tatttagatt ttgtatttgt ttatagttaa taagtggatt atagaattta taataattaa
     1861 tatatattaa acaaagatat attaagatat tttagaacac aaaactgcat taaggcgcga
     1921 gtactatttt gtattcgcgc cttgatggtt tgagttattt gagtaaaaac taactttaat
     1981 aagaaatctg tatttattaa gttgatattt ttaatgtgtt tagagattat ttaacaatct
     2041 ccaaatataa aactagaatt atttacataa aagttaaata gtttgtatag agttagattt
     2101 atatagtata atacttagtg taaataatta agaagttatc aaacaggagg ataaaactgt
     2161 gttagatata aattcttttt taaatggatt ttttaatata atattaagaa tgagtatata
     2221 tgatttaatt gacatatcta tagtagcgta tattttttac aaaatattta tgtttataaa
     2281 agatacaaga gcagaacaag tgtttaaagg tataatattt cttttattag caactcaact
     2341 tagtaacacc tttaaattgc ataccgttta ttggatatct cttaaagctt tagattatgg
     2401 agttatagct gctcttataa tttttcaacc agaatttaga gcaggacttg aacatatagg
     2461 aagagcaaag tttaatttat ttggaaagaa tgtaaatact tctgaagaaa ctctcaatag
     2521 aaatatagaa gaaattgtag aagctttata ttcactttct agacaaaaaa taggagctct
     2581 tatcataatg gagagagaaa ctagaataag tgatataata aatacaggaa ctattattga
     2641 tgctgaaatt tctaggcaac tattaataaa tatatttata ccaaatacac cattacacga
     2701 tggagctgtt gtaattagag attctaaggt aaaagcagct gcatgttttt tgccattgac
     2761 agaaagtaag gatttaagta aagatttggg tactagacat agagcaggaa taggggtaag
     2821 tgaggtgtct gactgtataa ctttgattgt atcagaggaa acaggtggcg tatcaattgc
     2881 taaagcaggt aagttatata gagatatttc tagagaaaga atgatgaata tattacgtag
     2941 taatttaaaa acaaatacag aaacaagaag ttttttcaaa ggtggtatat ttaaatgata
     3001 aatagactaa aaaataatac caaaataaaa ataatatcat ttttaagtgc aattgcatta
     3061 tggatgtatg ttatggctgt agttgaccct gaagaaacta aagggtttga agatatacct
     3121 gtatctataa gtaatatgag tgatttaaag gataaaaatc ttgttatata tccagacgaa
     3181 aaattaacag cagatgtata tataaaaggt agtttatcaa aggtacaaag tgttaaaaaa
     3241 gaagatatac atgtatatgg aaccattgaa gacccaatac aaggacagaa ggaagtatat
     3301 ttaaaagcaa atattcctca aggtgttact ctagaattta agcatgatgt tttagtagta
     3361 aatcttgaaa aaaacataaa agaaaaaaga gatataaagg tagaagtaag tggaaattca
     3421 aaaagaaata taaataaaat tgaacttagt aaggaatttg tcgatgtatc aggtccaaga
     3481 actctagtta aagaagtcaa aagtgtaaga gctaatctag atgttggtaa tgagacagat
     3541 gatttttcta aaaaattgca attaatacca ttaaatagtg atggaactaa ggttgaagga
     3601 gtaacattaa gttcatcctt tgtgactgca aagatagaac tattgaagga aaaaattgtc
     3661 ccaataagag taagtctaaa tgataataaa gataatgatg tactgaaaaa ctataaatta
     3721 agtaaggaac aagttacaat aaaaggaaag aaagaagata tagacaaaat aagttatatt
     3781 aagacaaaac ctattgactt agctgatttg gctaatggtg aagaaaaaga agttagctta
     3841 gaaattccag agggtataac tcttgaggat agctctataa caattaaatt aaatgataca
     3901 aaacaattga gtgcagaatt tttatataat gcgggagata ttgaattaag aaatatccca
     3961 acaaatatgg ataatccaaa tgtaatttct gatgtagata taaaagttgt tgtagagtca
     4021 acggaggatt tgagtaagtt aaataaaaaa gatatttcat tatatattga tttatcacaa
     4081 ggccctgagg aagatagtaa atataaaata aaatatgaaa caacatatca atttaaaaaa
     4141 ataaatatag aacctaatat tgttgaagtg gaatgaacaa atatttcgaa tatttagttg
     4201 ttacaagatg cgacaaaaaa acctataaaa ttaagtttgt taattttatg tttttgttgc
     4261 atcttgttta ttttagttat attataaaat aaggacaatg agatatttgt taaatctaaa
     4321 aagcgctaga tatatgaaaa aagactgata aatagattta aataaatatt ttgaattaaa
     4381 tatttcaatt atctctagga aaacgttgct gaacgagtta taatttaatt gagatataaa
     4441 aagttctatt tcaaaaaatt caagatgagg tggaaatgca tgagaagttt tgaagaagta
     4501 attaagtttg caaaagaaag aggacctaaa actatatcag tagcatgttg ccaagataaa
     4561 gaagttttaa tggcagttga aatggctaga aaagaaaaaa tagcaaatgc cattttagta
     4621 ggagatatag aaaagactaa agaaattgca aaaagcatag acatggatat cgaaaattat
     4681 gaactgatag atataaaaga tttagcagaa gcatctctaa aatctgttga attagtttca
     4741 caaggaaaag ccgacatggt aatgaaaggc ttagtagaca catcaataat actaaaagca
     4801 gttttaaata aagaagtagg tcttagaact ggaaatgtat taagtcacgt agcagtattt
     4861 gatgtagagg gatatgatag attatttttc gtaactgacg cagctatgaa cttagctcct
     4921 gatacaaata ctaaaaagca aatcatagaa aatgcttgca cagtagcaca ttcattagat
     4981 ataagtgaac caaaagttgc tgcaatatgc gcaaaagaaa aagtaaatcc aaaaatgaaa
     5041 gatacagttg aagctaaaga actagaagaa atgtatgaaa gaggagaaat caaaggttgt
     5101 atggttggtg gaccttttgc aattgataat gcagtatctt tagaagcagc taaacataaa
     5161 ggtataaatc atcctgtagc aggaagagct gatatattat tagccccaga tattgaaggt
     5221 ggtaacatat tatataaagc tttggtattc ttctcaaaat caaaaaatgc aggagttata
     5281 gttggggcta aagcaccaat aatattaact tctagagcag acagtgaaga aactaaacta
     5341 aactcaatag ctttaggtgt tttaatggca gcaaaggcat aattttaagg gggaaatagg
     5401 caaatgagca aaatatttaa aatcttaaca ataaatcctg gttcgacatc aactaaaata
     5461 gctgtatttg ataatgagga tttagtattt gaaaaaactt taagacattc ttcagaagaa
     5521 ataggaaaat atgagaaggt gtctgaccaa tttgaatttc gtaaacaagt aatagaagaa
     5581 gctctaaaag aaggtggagt aaaaacatct gaattagatg ctgtagtagg tagaggagga
     5641 cttcttaaac ctataaaagg tggtacttat tcagtaagtg ctgctatgat tgaagattta
     5701 aaagtgggag ttttaggaga acacgcttca aacctaggtg gaataatagc aaaacaaata
     5761 ggtgaagaag taaatgttcc ttcatacata gtagaccctg ttgttgtaga tgaattagaa
     5821 gatgttgcta gaatttctgg tatgcctgaa ataagtagag caagtgtagt acatgcttta
     5881 aatcaaaagg caatagcaag aagatatgct agagaaataa acaagaaata tgaagatata
     5941 aatcttatag ttgcacacat gggtggagga gtttctgttg gagctcataa aaatggtaaa
     6001 atagtagatg ttgcaaacgc attagatgga gaaggacctt tctctccaga aagaagtggt
     6061 ggactaccag taggtgcatt agtaaaaatg tgctttagtg gaaaatatac tcaagatgaa
     6121 attaaaaaga aaataaaagg taatggcgga ttagttgcat acttaaacac taatgatgct
     6181 agagaagttg aagaaagaat tgaagctggt gatgaaaaag ctaaattagt atatgaagct
     6241 atggcatatc aaatctctaa agaaatagga gctagtgctg cagttcttaa gggagatgta
     6301 aaagcaatat tattaactgg tggaatcgca tattcaaaaa tgtttacaga aatgattgca
     6361 gatagagtta aatttatagc agatgtaaaa gtttatccag gtgaagatga aatgattgca
     6421 ttagctcaag gtggacttag agttttaact ggtgaagaag aggctcaagt ttatgataac
     6481 taatgataaa agaataagaa tcataactgg tcactatgga agtggtaaaa gtgaatttgc
     6541 gatgaactat gttgttaagt taagagatat ggtttctggc aaagttgcta tagccgattt
     6601 agatgtggta aatgtatact ttagaactag agaaaagaaa gagttaatga aatccttagg
     6661 tatacaacca atagatagct caattaatgc tccaacatta gatttaccag cagtatcagc
     6721 agaggtaatg tctcctatgg tagaccattc atacaattct gttatagatt taggtggaga
     6781 taatgtaggt gctagggtta taggaagatt tagtcatttg ttaaaagaag gcgattatga
     6841 tatgcttttt gtaataaatg caaataggga gaaaactcaa acttctgaag aagttatcca
     6901 atatataaaa gaaatagaaa aatcttctaa attaaaggta acaggtctaa ttaataatac
     6961 tcatcttatt aggtttacta ctattgatga tgttttaaga ggtcagaaag ttgcaaaaga
     7021 agtttctgaa aaatgtaata taccgataag atatgttgca tgtttagaaa atcttgttga
     7081 acagttacca aaagatttag aaggagaaat ttttcctata aaattatata tgagagaaga
     7141 ctggatgtag tttgagctca aatatataga aagtttaagg aggcttaggt aaatggctaa
     7201 aggaaaagta tcttttaatc aagaacgttg taaaggttgt ggattgtgtg ttgaagcatg
     7261 tccagtaaaa atcatacaat tagactcaaa tgtaataaac aaaaaagggt ataacccagc
     7321 aactgttttt gaaatggaaa aatgcatagg atgtgcaagt tgtgcaacta tgtgtccaga
     7381 tgtagttata acagtagaaa gagattaatt taattaatat ttaaggggga attttaatgg
     7441 ctaagatact tatgaaaggt aacgaagcat ttggaaaagc agctatagaa gctggttgca
     7501 aatatttctt cggttaccca ataactccac aaagtgaatt accagaatat ttatcaagag
     7561 agttacctaa aataggtgga gcgttcgttc aagctgaatc agaagtttct gcgataaaca
     7621 tggtttatgg tggagcaggt gcaggagcaa gagttatgac ttcttcatct tcaccaggag
     7681 ttgctttaaa gcaagaaggt ataacatatg cagtaggagc agaagttcct tgtgttgtac
     7741 ttaatgtaat gagaggtggt ccaggacttg gaagtataca accttcacaa gctgactact
     7801 ttatgtctac aagaggtgga ggaaatggag actacagaac tccagtattc gcaccagcta
     7861 cagttcaaga agctgttgat atgataatgg aagcttttga cgttgcagat tattacagat
     7921 caccagttat ggtagttgca gatggtatga taggtcaaat gatggagcca gttgaattta
     7981 gagctcctga gaagaaaaga gaattgcctc ctaaagattg ggcaactgtt ggaactaaag
     8041 gaaaaagaaa acctaatgta ataaactctc tatacttaga gccagaagta ctagaagacc
     8101 attgttggca tttacaagaa aaatttgatg caatggaaaa gaatgaagta caatacgaaa
     8161 tgtacaaaac agaagatgct gaatttgtat ttgcagctta tggaactact tcaagagtag
     8221 taaaaagcgc aattgatata ttaagagaag aaggaataaa agcaggtctt ataagaccta
     8281 aagtattatg gccattccca ttcgaagcat tcaaccaaat tcctaatgct agaaacatat
     8341 tgactgttga aatgagtatg ggacaaatgg tggaagatgt taaaatggca gtagaaggta
     8401 aattaccagt ttacttccat ggaagaccag gaggaatgac tccaacacca gcagaaatag
     8461 ttgaaaaagc taaaaaaatt attgccggag aattggttgc aggaggtgct agataatggc
     8521 tgttgtattt aagaaaactg aaggattaca agatactcaa actcactact gtccaggatg
     8581 tacacatggt ataatccata gattagttgg tgaagtatta gaagaactag gagtattagg
     8641 tgatgctgta ggtgttgttc cagttggatg ttcagtttta ggatataaat attttaactg
     8701 tgacactcaa gaagctgctc atggtagagc gccagctgct gctacaggaa taaaaagagt
     8761 tcatcctgaa aatacagtat tcacttatca aggtgatgga gacttagctt caattggtac
     8821 tgctgaaata gttcatgcag ctgctagagg agaaaaaata actactatat ttgtaaacaa
     8881 tacaacttat ggtatgactg gtggacaaat ggctccaact acattagttg gacaaagagc
     8941 tactactgct caatcaggaa gaaatgctga aactcaaggt tatccaataa gagtaagtga
     9001 aatgttagct acattaacag gagctgtatt tgtagaaaga gtagcagttg atactccagc
     9061 tcatgttaga caagctaaaa aagctataaa gaaagcattc caagttcaac aagcaggatt
     9121 aggatttgga atagtagaag tattatctac ttgtcctaca aactggggac tagctccaaa
     9181 tgatgcttta caatggttaa gagacaacat gataccatac tatccattag gaaatttcaa
     9241 aaatgttgaa gttgaggagg tgaagtaaat gtctacagct agagtaatat gtgcaggctt
     9301 cggaggccaa ggtgttatgt ctatgggaca attacttact tatgcaggaa tgctagaagg
     9361 aaaagaagtt tcttggttac catcttatgg accagaaatg cgtggaggta cagcaaactg
     9421 tgcagtaact gtatctaatg agccagttgg ttctccactt ataacagatg atgcaactgc
     9481 agctatatta ttaaatatac cagcatttga aaaattcaaa gatgatgtta ttcctggtgg
     9541 aaaaataata gtaaatagtt ctttaataaa agaaaaagtt gatagaacag atgtagatgt
     9601 ttattatata ccagcaaatg aattagcagc tgaattagga aatgataaag ttgctaacat
     9661 gataatgtta ggcgcttact taaaagtatc tgatactgta gatatagaat ctgtactaga
     9721 agcattcaaa aaagttttcg gacctagaaa agaaaaattc gttccattaa acagagaagc
     9781 tttacaaaaa ggtatggatg ctacatgttc taaagcaact aactaataaa gaaaaagatg
     9841 tcaaaaaaaa gacaatagaa ttatttctat tgtctttttt gctgataagt attaaaatat
     9901 ttttatgact gaaattaagc ctataatgat attttatgaa ctataaaaat ataatacaaa
     9961 ttacaagctt ttcaattatg aaaggagaat ctttagtgag aaagtatttt ggaacagatg
    10021 gagttagagg agtagcaaat acagaactaa catgtgattt agcatataaa cttggtagag
    10081 ctggtggatt tgtcttagct caaggagacc acagagtaaa agtagtagta ggtaaggata
    10141 ctagaatatc aggtgatatg ttggaagcat ctttaatagc aggacttatg tctgttggat
    10201 gtgatgttat tactgttgga ataataccaa cacctgcagt ggcatattta actagaaaat
    10261 atggtgctga ttgtggtgtg gttatatctg catctcacaa tcctgttgaa tataatggaa
    10321 tcaaattctt taataagaat ggatataaat tagatgatga aattgaattg aaaatagaag
    10381 aatatataga cgatatagac aaaattgatt gtcttccaat tggtgaaaat gtaggaagaa
    10441 aattacatga acattgtgca caaagagact atgtagacta cctaaaatca ataataagca
    10501 ctgactttaa gggattaaaa gtagttttgg actgtgctaa tggtgcgtca tataaagtgg
    10561 caccaatagt gtttgatgaa ctaggagcaa gtgtaatttc aataaatagt tcaccagatg
    10621 gaaataatat aaactataaa tgtggctcta cacatccaga acaacttcaa agggctgttt
    10681 tggaacataa tgctgactta ggtcttgcat atgatggaga tgctgataga ttaattgcag
    10741 taaatgaaaa gggtcaaatt gttgatggag accatataat gatattgagt gccttaaatt
    10801 taaagaaaaa taataaattg gcacaagata ctttggtagt tacagttatg agtaatatag
    10861 ggttgacaat agctgctaag gaaaatggaa taaatttatc tactacagca gttggagaca
    10921 gatatgtttt agaagatatg gttaaaaatg gatataatct tggtggagag caatctggac
    10981 atatgatatt tttagattac aacactactg gagatggagt gcttagttct ctaatacttg
    11041 caaatataat cttgcaagaa aagaaacctt tatcagaaat tgcatcaata atgagccaat
    11101 acccacaagt attagtaaat gcaacaataa aaaatgaaaa taagaacaaa tatatggaat
    11161 atccagaaat aaaaactgag atagaaagaa tagaatctat tttagacgga aatggtagag
    11221 ttttgataag accatcagga actgagccat tagttagagt tatgttagag ggtaaagagg
    11281 aaggtcaaat aaaagaatta gcaacaaact tagctaatct tatacaagaa aaattatcgt
    11341 aatttaaagg gtattctcag atataaatac tgaggacacc tttctaagcg ccagaactta
    11401 gttatagaca taattattga gtaatatagg aactaagttg acgaggtcag agttaatcga
    11461 attgtcggcg gatgctctgc ggtgtgttta ccatcgaaag acttctttaa ataataggag
    11521 caatcctatg gacaaaggga agccaaagta aacttatatg acctaactct taaaatatat
    11581 aaataatatt tttaggagga cacaaataat gtgtggaata gttggatatt taggaagtag
    11641 aaaggcagca gaagttatag tagaagggct ttctaagcta gagtacagag gttatgactc
    11701 agcaggagta gcagttaata gttctaatga aaaagaactt aatattagaa agtttaaagg
    11761 tagactttct gtacttgcag aagacttaga aaagaatcct attgatggaa atttaggtat
    11821 agggcatacg agatgggcaa ctcatggaga accatctgat gtaaactcac atcctcattt
    11881 taatcaagcc aaaacaatag cagttgttca taatgggata atagaaaact atatggaaat
    11941 aaaagaagaa ttaatttctg aaggtgttaa gtttgaatct caaacagata cagaggtaat
    12001 agcacattta gtagataaat actatgaggg taatttatta gatgctgtat acaaaactat
    12061 atcaaaatta agaggagctt atgcattagg tgttatatgt aaagaacatg gaaatgaatt
    12121 agttgcagta agaaaagata gtcctcttgt agttggtgtt ggtgaaggtg aaaactttat
    12181 agcatcagat atacctgcat tattaaaata tactagagat gtttatttct tagaaaatgg
    12241 agaagtagtt catctaaaag acgaaaatgt aaccgtttat gactctaata gaaatcttgt
    12301 tgaaaaagaa gtatttcatg taacttggga tgtagaagct gcgtctaaag gtggatatga
    12361 ctactttatg tcaaaagaaa ttcatgagca accaacagga gtaagagaaa ctttagaaag
    12421 aagacttgat gataatggaa atataattct agacagtata aatatttcta aagaagactt
    12481 agaaaaaata aataaagttt atatagtggc ttgtggaaca gcatataatg ctggattact
    12541 tggtaagtat gccatagaaa aatttgtaaa tataccagta ataactgata tagcatcaga
    12601 atttagatat agcgacccat ttgtagatga aaattcatta gtaatattag ttagtcaatc
    12661 tggtgagaca gcagatactc tagcagtatt aagagattca aaggctaaag gagcaagaat
    12721 actttcaata actaacgttg taggttcatc tatagcaaga gaatcagatg atgtattcta
    12781 tacttgggca ggacctgaag tagcagttgc atcaactaag gcatatacta ctcaaataac
    12841 ttctttatac atgatagctt tagactttgc tatcaaaaaa ggaacaataa ctagagaatt
    12901 ttatgatagt atgatttcta agatgaaaga aataccatca aaaatacaag aaatactaga
    12961 caatgaagaa tatataaaag aagttgctaa aacagttgtt agttctgaac atgcattcta
    13021 tttaggaaga ggtatagact atagcttagc aatggaaggt tcattgaaat taaaagagat
    13081 ttcatatata catgcagaag cttttgcagc aggagagcta aagcatggaa caatagcttt
    13141 aatagaaaaa ggaactcctg taattgccat agctactcaa gaaaagttat ttgaaaaaat
    13201 ggtttctaat atggaagaag taagagcaag aggagcttat gtagtagcaa tagctcaaag
    13261 ccataataag gatgttgaga aagctgctga taaaataatc tatataccaa attcagatga
    13321 tattttatca ccaatattag cagttgtacc aatgcaatta cttgcttatc atgtctctgt
    13381 actaagagga tgcgatgtag ataagccaag aaatctagct aaatcagtaa cagttgaata
    13441 aaaacagatt aaaaattaaa tagataatat ttattgaaaa gaactcatcc tgttatttgt
    13501 attttatagg atgagttttt tagataaata ttaaatttgt tttgtttttg ctataataaa
    13561 ttttataaaa agattgatat taaatcatct gtaaaatgat aaatatatag accataccag
    13621 gtatagggaa cgataaatat agttcatata aaatatagtg agtacttaat aaacatatag
    13681 tcaatatcag ataaaaaaaa taatagctta tgagaaaaat taaaatacaa ggtattagta
    13741 accttgtgat aagataaagt gagtagttta aaataagaat ataaggaact atttataaaa
    13801 gaatataatg aagctaatag agtataagaa aattacttta ttttagtaaa ataatttcaa
    13861 ataaaaattt ttttaaattg ggagtataaa ttatgacaaa tgattttaaa aaagaaaaga
    13921 aagaagatta ttttgttaat cttaaggcaa tatctactga agttttacaa gaaaaagtgc
    13981 aagataacgc ttgggttata gttgatactc gcttaaatga tgcttataat ggctggaagt
    14041 tagatggagt aaaaagaggt ggacatataa aaggagcagt agatttttct gctaattggt
    14101 taagtgtata cttagataga aaagatgaag tgttagaaca agcattgaaa actaaaagaa
    14161 ttgatttaga taaaaatata gtattgtatg atgcaaatgg aaaagatgct ttggttgtag
    14221 cagattattt atctaaaaaa ggatataaat atctatataa atatgatatt aaacaatggg
    14281 cagacgacga aaatcttcca atggaaagat ataaaaatta tcaaatgata gttcctgctt
    14341 ttataataaa agatatatta gatggaaaaa ttcctgagac atttgaagat tcaaagaata
    14401 taaaaatgat tgaagcgagt tggggagaag aatcgtatac aaaagggcat atacctacaa
    14461 gtgttcatgt aaatactgat attatagaac ctcctccaac atggatgctt gataatgatg
    14521 ataacttaac taagtttgct ttagactatg gattaacaaa ggatgatact gtaatagttt
    14581 caagtagtac acctatggca tcttatagac tagctgttat attgagatat ataggagtaa
    14641 aagatgtaag agttttgaat ggtggaacaa actcatggtt atcagcagga tatgaattag
    14701 aatttattag taatccaaaa cattcatgta ctaattttgg agcagatata ccagttaact
    14761 cacaattagt tgttactaca tctgaattaa gacaaaaact aaaagaaaaa aataagttta
    14821 tactagtaga taaccgtact tgggatgaac atataggaaa agtatctgga tatacatatt
    14881 atgataaaaa agggcgtata ccaggagctt tatatggaca ttcaggtagt gatagtgttt
    14941 cactagaaga atatcgtaat attgataata caatgagaaa taaatatgag attttagaaa
    15001 tgtgggacaa ggaaaatata gatgtgaata aacagcttat atttatgtgt ggaagtggat
    15061 ggcgtgctgc tgaagtatta acatatgcaa atgtcatagg agtggaaaat acctcccttt
    15121 atagtgatgg atggatgggc tggagtcttg ataattcaaa tttaattgaa gtgggagaac
    15181 acaaataaag tttttgaaag tacaatagag ttgtttaaaa caaaggtgtt tttgatttat
    15241 taggaagagt gtgtaaattg tgtattggga agtggactta ggtatgttca tttggagcta
    15301 tggaaactga taaaaaagta ttatctgttt attttgctgg taaaatatga atagattata
    15361 gattatagat tatagattat agattataga ttatagatta tagattatag atttaagtat
    15421 agactaagta atttatatta cagaagagaa tatataagaa ttaatgcaag atgtatttga
    15481 tacatataag aaattggcaa gtccaggaga aggatagaga aaattgagat tgaagagttt
    15541 gaaagagatt attagatgaa aaatacaaaa atgtataaaa atacatattg agaaagtata
    15601 tctctcttaa atttgttaat aattctatta tacagaaaaa catatttaag ggggattttt
    15661 tactatgaaa aaagtaaaat tagctataag cttttttata ttaatgatta taggaatgac
    15721 aatatcttat gcagatacaa gtataaatac tagatacaat agattaagta aagctcttga
    15781 aatatcagaa gcaaatttta aattttataa tgttaaaatt aattctgtta taaatcataa
    15841 tttatcaaat aaagaatttc ataatatttt tatagaaata attaacaatc taaagttgga
    15901 taaaaaagga ataaattgga atcaaaaagg gtctggcgat aaaatacaat tatgtgctac
    15961 tataaaaggt agcgataaag aaatttctat aaaaggaata aataaaaata acaaagaaag
    16021 ttacatagta gttgacatat tggataacaa agtatataaa cataaagagg ttatttatag
    16081 taacgtagaa aatgtgttaa ataaatattc atctcaagta gatgtgtctg cttgtattgt
    16141 tggagaatac acaaaaaggt tacaaaacaa caaatatgat gatattttac aaaaaatatt
    16201 atataatatg agtgctaagc aaatagatga agttaaagac gtaaactttt tatctataac
    16261 agcatatagt aaagtattaa atgattatga attagaatat ttaggggaaa aaattaattt
    16321 aaatatagga attaaatata atgaggatga cggaaaaaca ctcatatata ttgccacacc
    16381 aattataaaa ttagattatt aattatgagg agatcaaaaa atatggctaa gataatagta
    16441 aaaaagagta atccacttaa aggtagtgtt aaaatagatg gtgcaaaaaa tgcagtttta
    16501 ccaataatag cagcgacttt attagcaaac ggaaaatcaa cattaaatgg agtaccaaat
    16561 ttaagagatg ttcatgttat atcagattta ttaagacatg taggagcaga agttgaatat
    16621 aaagaaaata cacttactgt tgatgcaagc aatataaaaa cttgtgaagc tccatatgag
    16681 cttgtaagaa agatgagagc ttcttttttg gttatgggac cattgcttgc tagatttaat
    16741 agtacgaaaa tttctatgcc aggaggatgt gctataggaa caagacctat agatttacat
    16801 ttaaaaggat ttaaagcctt aggtgcaaag atagaaatgg accatggttt tgttgaagca
    16861 gcaacagaaa agttagtagg aaataaatta tatttagatt tcccatctgt tggagcaact
    16921 gaaaacataa tgatggcagc ttctttagca gaagggacta caataataga gaatgcagca
    16981 gaagagccag aaatagtaga tttagcaaac ttcttgaacg aaatgggagc agatgttaaa
    17041 ggtgcaggta ctaatactat aaaaataaaa ggtgttaaag agttaaaagg agcagaacat
    17101 aatgtaattc cagacagaat agaagcagca acttatatgg ttgcagcagc tatgacaaaa
    17161 ggtgatataa ctgttgaaaa tgttttaatg gagcatttaa aaccagttgt agctaaatta
    17221 agagaagctg gttgtgaaat aacagaaatg gacaattctg taagagttgt aggtccaaaa
    17281 gtattaaaac caatagatat aaaaacttta ccacatccag gatttcctac agatgttcaa
    17341 gcacaattta tggctatgct tactgtagcc aatggaactg gtgtagttat agaaactgtt
    17401 tttgaaaaca gatttatgca tgttgctgaa tttaatagaa tgggtgctaa tataaaaata
    17461 gatggaagaa gtgcggttgt taatggtgta gatgagctac acggtgcagc agtaaacgct
    17521 actgatttaa gagcaggggc agctcttatt ttatgcggtc ttatagcaga aggagaaact
    17581 caaataggag aaatatacca tatccaaaga ggttatgttg atatagataa gaagataaca
    17641 gcactaggtg gtcaaatcga aatagtagaa gattaataat tggtttatag aagaaagtta
    17701 taaattaata gggttgttca tatacttaaa tacaaggttt taaaagctaa ggaggagagt
    17761 atatgaagaa cccattggtt gttttgttag gatttgtgac ttgctctgtg ttagttccat
    17821 cacttataac tttagtttct tataaaaatg tagaattaac tgaaaaacca gagagcccag
    17881 tatctataaa caaaactatt aaaaaaagtg atattgaaga caaaggtaat aaagaagaaa
    17941 aaaatacagt gaactatgaa actgtaaata aaaaagcacc aattatcaat gtatataatc
    18001 atataacagg gaaaaccgaa aagatggaca tggagaacta tttatgtgga gtactagctg
    18061 gtgagatgtc ttcagagttt gatatagaag ctttaaaagc tcaatctgta gcagctagaa
    18121 catatgtagt atataaacag gaacatggta aatctagtaa acataaaaat gcagtagtat
    18181 gtactgatta taaacattgt caagaatata agagttatga tactcttaaa aaattaaatg
    18241 gtgaagaatg gattaagaat aaatattcca aaatccaaga agcagttaga ggaactaaag
    18301 gtcaaataat aacttataat gataaggcga tacttcctct ttatttttct acatcttcag
    18361 gaaaaacaga aaatagtgaa gaagtatttt ctgcaaaata tccttattta aagtctgtgg
    18421 aaagtcctta tgataagtat tcccctaaat ttgcgtcaac acttaaaata agtaacacag
    18481 attttgttaa aagtcttaga agggcatata gcactattgt gatagatgtg aataatttaa
    18541 gtaaacaagt ttcaataact aaaagaagtg atgccggaac tgtagaaaaa ataaaattag
    18601 gaaataaaga attgactgga aaagacatta gaactgtttt taaattgaac tctgcaaact
    18661 ttgacataaa atttggagaa ggatacatag atttcgtggt aaaaggatat ggtcatggtg
    18721 ttggtatgag ccagtgggga gcagaaggaa tggcagaaga gggctataaa tattatgata
    18781 tattatcaca ttactacaca gatacaaaaa taaaagatat atactaataa ttgtataaaa
    18841 tgccaaaaac acgtcaataa tccaaatgta gaaatatatt tggaggtgca aaatgaagaa
    18901 aaagctgtta gaaaaagatg gtttttattt atctttgttt gtatgtgttt gtttattagc
    18961 agtaggtgga gtttggttta caaataataa tgtagataaa ttggcttcta ataaaggaat
    19021 tatggaaaat gctaataaag atagtgaaga ggaaatacat ttaattgaaa aagacaagaa
    19081 agatgctatc cctactgcaa cggattcaaa acaaaactta gaaaaagcta agtcaaaaga
    19141 ggaaaataaa tcgagtacaa caaaattaaa ttacattgga gataaagtaa taagaggata
    19201 ttcagaaaaa gagcctagtt attctaaaac acttgatgtt tgggaaactc ataaaggtgt
    19261 agatattagt tgtactaaag gcaaagaagt aaaatctcta ttaaacggaa tagtagtaga
    19321 tgtatttgat gatgaagaat atggacaatc agtcaaaata aaaagtgaca ataacattgt
    19381 agtagtatat tcaaatctag ataaaaatgt tagtgttaag aaagaacaga aggtaacaga
    19441 aggacaatct ctaggtactg taggtagtac ttctcaaata gaaagtgaag aaggtataca
    19501 tgtgcattta gaggcgtata gtggagaaaa atctatagac ccaatgagtc taattaagta
    19561 atagtataac aagtttaatc atatttggtt aagcttgtta tattttttgg tgtttttaca
    19621 tatatatcat taaagctatt atgtgagggg ggtaatcttt gagatctcat atagaggaaa
    19681 gggccatagt ggtagcaaaa tatatacttg aaaaaaacac tacagtaaga caaaccgcca
    19741 agacatttgg agtaagtaaa agtacaattc ataaggatgt tacagaaaga ttgaaggaaa
    19801 taaatccatc ccttgccaaa gaagttaaaa atgtgctgga caaaaataaa tcagagagac
    19861 atattagagg gggattagca acgaaattaa aatatgagaa ggaacataaa aaaatgtagg
    19921 ttaaaaacct acttttttta ttgaattaaa ttataaaaag aaatatatta agtaattata
    19981 aatagcaaaa taataatact ctcaaaagat ttattttctc ttgattaaag cgagattttt
    20041 gtatatgctt tattatagga gtattaaaat atgcttataa tataatctaa tattataaat
    20101 aaaggagttg aaaaaatggc tggagctgat ataggcatag atttaggtac tgcaaatgtg
    20161 cttgtttatg ttagtggtaa gggaatcgtt ttagaagaac catctgttgt ggcgatagac
    20221 aaaagaacag attttgtttt agctgtggga gaagaagcta aaaagatgat agggagaaca
    20281 ccaggtaata tagtcgctat aagaccttta agagatggtg taatttcaga ttatgatgta
    20341 actgagaaga tgttaaaatc ttttatagat aagatagttg ataaaaaggg atttggaaga
    20401 ttttttatgc caagaattat ggtatgtgta ccaacaggtg tcacagaagt ggaaaaaaga
    20461 gcagtagaag atgctacgag acaagctgga gctagagaag tatatatcat agaagaacca
    20521 atagcagctg ccataggagc tggtgtagac atatcacagc ctaatggtaa tatgattata
    20581 gatattggtg gaggtactgt agatatagct gtaatatctc taggaggagc tgttgtaagt
    20641 gaatctataa aggttggtgg agatagattt gatgatgcta tagttaaata tatgaaaaaa
    20701 caacacaatc ttcttatagg agaaagaaca gcagagaaaa tcaagtttga aataggttct
    20761 gcatttaaga gagaagaaga aaaatatatg aagataacag gaagaaattt aattacagga
    20821 cttcctagtt ctataactat aaattcaaca gaaatgttgg aagcacttag agaatgtgtt
    20881 gagcaaatag tagttgctac tcatgctgtt ttggaaaaaa cgcctcctga gttagcagca
    20941 gatataggag atgtcggtat aataatgact ggaggaggtt cattattata tggattagat
    21001 aaaataatag aacagaggac aggaataact gttacaatag cagatgaacc attatcttgt
    21061 gttgcaaaag gtacaggaat agctttaggt tcaatagact tacttgaaac tggtgggtct
    21121 ttcaaaagaa aataattagg agagtttaga atgttaaata tagatgaaat aaaaaaatta
    21181 ataccacata gatatccatt tttattagta gacaagatta cagagctaga agttgggaaa
    21241 agagctgttg gtataaagaa tgtaacagtt aatgagccat ttttccaagg tcactttcca
    21301 gaatatcctt tgatgccagg agtactaata gtagaagctc tagcacaagt atgtggagtg
    21361 gcaatgatgt ctgtagagga aaacaaagga aaactaggtg tatttgcagg tatagataaa
    21421 gttagaatca agagagaagt aagaccagga gatacattaa ctatggaagt tgaaatgaca
    21481 actcttagaa aaaatatagc taaggcagat gctaaggcat atgtaggtga agaacttgtc
    21541 tgtaaaggtg aattaatgtt tgctttagta gaaaaataaa aacttgaaat ataaaagtaa
    21601 aaaggtagat aatttggagt atttaatcag atactctaaa atatctacct ttttatataa
    21661 agaattttat catttagttt atatttagat taggtggata ctaataaagc caaggctatt
    21721 gtttcagcta aatctaatat aaagctaagg cgtatattat taaatgaaag tttattattt
    21781 tcatcaattt tatctacaat tcctactata gaataatttc ctatttgagg tagtttttta
    21841 ccaacacctt ttccgggcag gataggtcct tctctaatct gtatattacc tatgttactc
    21901 tgcgacccca agcaagcatc tatagccaag aagttacctt gtatatgtgt attttttata
    21961 gtatctaaag actcatatat atttaaggcg tgaatagggt tatctagtgt accgtaaacg
    22021 gggtatttaa agttactgtt cttaagtatt gttccaacta aagggcctaa agtatcacct
    22081 atagccctgt ctgttcctat gcaaacaaca atcgtatttt cattaattat agtttttaga
    22141 actgaactta gcatctgtat aacatcatca tcgctgtagt ttactttagc taaatacaat
    22201 aggaacaccc ccttcaaaaa aatatatgaa taaaaagcat taaaaagacc taactttaaa
    22261 tttcagatag atagaaaatt ttatttgtct tacaaaaaaa ggaatagaaa aaatatgact
    22321 aaaaatattg acaaaatttt aaaaaaatag taagctagta aagtaaaaca aaacttaaat
    22381 cttgattacc ttatcaagag aggctgaggg ataggccctg tgaagcccag caaccaccca
    22441 aatgggaaaa ggtgctaatt cctacaagac aaaagtcttg aaagatgagg tcagttaatt
    22501 agtatgtaat tacgattatt aacctcttct tataaaggag aggttttttt attttgagta
    22561 aatttctaaa attaaaaata aggtaaaacc tataataaaa attaagaata aataaggggg
    22621 aataaaaatg gcaagacatt tatttacgtc agaatcagtt acagaaggac atcctgataa
    22681 gatatgtgac caaatatcag attcaatatt agatgcatta ttagaaaaag acccacaatc
    22741 tagagtagct tgtgaaacta cagttactac tggtttagtt ttagtagcag gagaaataag
    22801 tacatctgct tatgtagaca ttcctaaatt agtaagagaa acagtaagag aaattggata
    22861 tacaagagca aaatatggat ttgattgtga tacttgcgca gttataactt ctattgatga
    22921 acaatctgga gatatagcta tgggagttga tgaaggtcta gaaagtaaga ctggagaaga
    22981 gatagaagaa gaaatagaaa aagttggagc tggagaccaa ggtataatgt ttggatttgc
    23041 atgtaatgag actccagaat taatgccact tccgatatct ttggcacata aattatcaag
    23101 aagacttaca gaagttagaa aaacaggttt agttgattat ttaagaccag atggaaaaac
    23161 tcaagttact gttgaatatg aaggaagtaa agctgtaaga gtacatacag ttcttatatc
    23221 agctcaacat tgtgaaacag tatcaaatga taaaataaga gaagatttaa ttaatcatgt
    23281 tattaaggaa gttataccag cagaattact tgatgaagag actaaaattt atataaatcc
    23341 aacaggaaga ttcgttatag gaggaccaca aggagataca ggtcttacag gaagaaaaat
    23401 aataatagat acttatggtg gatattctag acatggtgga ggagctttct caggaaaaga
    23461 ccctacaaaa gttgatagat ctgctgctta tgcagctaga tatgttgcaa aaaatattgt
    23521 tgcggctggt cttgcagaca aatgtgagat agaacttgca tatgctatag gtatagctag
    23581 accattatct atatttatag atacttttgg gacaggcaag gtttcagaag aaaaacttgt
    23641 tgaattagta aataaacact ttgatttaag accgggagcg ataataagag acttagattt
    23701 aagaaagcct ctttataaaa aggttgctgc ttatggtcac tttggtagaa ctgatataga
    23761 tttaccttgg gaaagaactg acaaggttga gcagttaaga aaagatgctt taggtgaata
    23821 atttttaact aaaaagctgt tagaatgtaa ttttatgatt actttctaac agctttttta
    23881 ttatgagtta aatattttta ataaatgtta atttatcatc atataatgaa taaacagtat
    23941 ttaatctggt caatacattt tatataatac tctactaaat ttatacatat tatgggatat
    24001 atgttaaaga atggttaaga atgtgttaac taatgttaaa taattaaaaa tatattgaaa
    24061 tatcacaata atgagtctaa tataatctta ataaacttac actttaaaaa taattttaat
    24121 tgggggggga gtagtgtatg tcaggcaaag taaatattaa aacggttata agttttgctg
    24181 gagcttatgt tgctactgta ataggttctg gatttgcaac tggtcaagaa atactgcaat
    24241 tttttacgtt ttatggatat gcgggtatta taggtggaat aatctctatg gtactatttt
    24301 catggtttgg agcagaagtt atagataagg gaagagaatt gaaacttaag gagccaataa
    24361 aaatttatca agtatattgt ggaaaatatc ttggaacatt ttttgaatgg tttggtccat
    24421 tgtttttatt tggaacatta gtaataatga ttgcaggagc aggagctaca ttatcagagt
    24481 actatggatt aaatccatat gtaggtagga ttggtatggc aatcgtttcc ctaataactg
    24541 tttcattagg tttgacaagg ctttctaaaa tactaggtaa tataggacct ataataataa
    24601 tatttacact tttagtagga gcaattagtt tatttagcaa tattgatgct ttatcaaatg
    24661 ctggaaatat ggttgatagt ttaaatatta aaactgctac atcaaatgga tatttctcgg
    24721 gagtacttta tacttgttac aatgtaataa tagtaataac attcttgaca ggaatgggag
    24781 cttctgcagt aaataagaaa gatgctgtat ggggtggtat agtaggtgga gtagcactta
    24841 tggcagcagc tataatgatg aatttggcat tactttcaga cataggaaat atatacacaa
    24901 aagagatacc agcactttac ttagctgata agatatctcc agtaataggt attttattct
    24961 cagtagtact tttactagga atatacacta cagctgtacc attgttatgg tcagtaacaa
    25021 accgatttgt agaagatgac caccctaagt ttaaaattat aacaatagtg gtaagtatat
    25081 tagcttgtat aggaggttta ctgccatttg ataagttagt aggtacacta tatccatata
    25141 caggttacat gggaatttta attttactat gtatgcttta tagaagaatt actaaaactg
    25201 aggggtacaa ggagaataaa tctgaaataa gttagtactg taatatactt atgaaattta
    25261 atttatactc taaatataga gtaattaaaa taaaatagct atttaaatat ggtacctgta
    25321 tttcatggta ccatatttta tggatgcaga ttttttttgt ttctgataaa atgtataata
    25381 gttggaaatt acgttaagta taaaaatata aaacttttct acgattatca tggttttaat
    25441 atataaaatt atactaacat ttaaatggag cgattattag tatttttagg agataaaaat
    25501 ggaaaaatta gaaggaatga taagtgaaat agtctttaaa aacgaagaca atggttatac
    25561 aatagctcac ctggtaaatg aaaatgatga aattgtggtt gtaggatgta tgcctacttt
    25621 ggcaattgga gaaagcatag aagttgaagg aaagtgggta aatcataaga tttatgggac
    25681 tcaatttgaa gtgaatagtt ttatgccagt aacaccatca tccttagaag gaatttatgt
    25741 ttacttatct tctggaatga tacatggtat tggtgaaaaa atggcaaaaa gaataattga
    25801 taagtttggt gtagatacgt tagaggtgat acaaaattca ccagaaaaac tacaagaagt
    25861 agaaggtata gggagtaaaa aagtaaaaca aatagtaaaa agttatgaag aagacagaga
    25921 attgagaaat ataataatac agctatctcc ttttggaata acaccaaatt actgcctaaa
    25981 aatatataaa aaatataaaa gcagtgcaat agaagttata aataaaaacc cataccaact
    26041 tgctgaagat ataagaggaa ttggatttaa agtagctgat agtatagcaa gtaaaattgg
    26101 tatagataaa aactctaaag atagaatttg tcagggaatc ttatacactt taaataaatc
    26161 tttaagtaat gggcatacat atttaccaga gcatgttcta atacaagatt cggaaaaatt
    26221 gttggagcta aatggagaaa tactaaaaga gtgtgtaatg atgctagttt ataatcaaaa
    26281 aatacatata gagaaagtaa acaatgaaaa tcttatatac cttatgccat actatttagc
    26341 tgaaaatgga gtatgtagtc aaatagtaaa attatcacag tatgaatttg aagacttaaa
    26401 aatagatata gataacgaga ttaatgtttt agaagaagat aagaaaatta agttagcaga
    26461 aaaacaaatt ttagcagtca aagaatctgt taatagtgga gtattaatta taactggtgg
    26521 accaggaact ggtaaaacaa ctaccattaa tgctatcata gatatatttg aaaataatgg
    26581 taaaagtgtg actttggcag ctccaacggg aagagcagca aagagaatga gtgaaacttc
    26641 taataaagaa gcaaaaacta tacataggtt gctagaaatg ggattttcaa cagatgatga
    26701 tttaactttt tttaaggatg aagaagaccc aataaattca gatgtaataa ttgttgatga
    26761 ggtatcaatg gtagacatta tcttaatgta caatttactt agagctataa agttaggaac
    26821 aagagtaatt ttagttggag atagtgacca attaccttct gtaggtgctg gaaatgtact
    26881 taaggatatg attaattcta atattataaa tgtagttaaa ttaaatgaaa tatttagaca
    26941 agcgcaagaa agtatgataa ttgtaaatgc ccataagata aacaatggag aaccacttta
    27001 tctaaataca aaaggtaaag atttcttttt tataagaaaa tcaactaatg aagaaatttt
    27061 aaatgaaata ataggattgg ttaatgaaag attacctaaa ttttataaag ttgataaatt
    27121 aaaagatata caagttttat cttcaatgag aaaaggtgaa ttgggagtta ctaatctcaa
    27181 tatagagtta cagaagtatc ttaacaaaaa agaaaaattt aaagttgaag aaagtttttc
    27241 taaaagatta tttagagttg gcgataaggt aatgcaagta aaaaataatt atacaaaaaa
    27301 atgggaaaca gaagaccaaa aagaaagtgg agaaggtatc tataatggag atataggata
    27361 tgtttatcac atagataaag ataagaaaac tatttatata ttatttgacc agactaaaat
    27421 tgtatcatac ctatatgatg aattagatga aattgaccat agtttttgta caacaataca
    27481 taaaagccag ggaagtgaat ttccagttgt agtattgcca atagcgtggg ctcctcctat
    27541 gttacttagc cgtaatttat tatatacagc agtaacaaga gcaaaaaaat tagttgtatt
    27601 agttggagat gtgaaatatc ttgaatatat gataaaaaat aatagagtta atcaaaggta
    27661 ttcaaattta ggatataagc taaataaatt taaacaagaa gggttgttga tagaataaat
    27721 atgaaaatat gcaatgataa ttttattaag aattttaaaa atatgattaa taaatgtttg
    27781 gattttatat atcctgagaa tataagttgc ataatttgtg ataaatccat aaagaaaaca
    27841 aatacttatt caatatgtaa aagttgtttt aaagaaatga attttataca agatggttgc
    27901 atgaagtgtg gaaaaccaat aatacgtcat tcaattgaaa aagaatttat tgaagagtgt
    27961 agttattgtt ttaataaaga cttttatttt gataaatcaa tatcttgtat tgaatacaat
    28021 gatgtgacaa aaaagatggt gttagggctg aagtataacc aaaaaacctt tatggctaag
    28081 tatatagctc aaataatgaa agaaaaatta tatttagaaa acataaaatt tgattatata
    28141 ttatttgttc cacttcataa aaaaaggcta aataaaagag gttttaatca ggcacaaaaa
    28201 atagcattta atttaagtaa aatagtaaat attccattat tagattgcat aagtagaaaa
    28261 aaatatacaa gaatgctata taaattgaat aagaaagaac gaaaagaaga attaaaaaat
    28321 gtatttgttg ttaaagaaaa tgttaaatta ataaataata aaaatatact tttaatagat
    28381 gatatattta ctactggtct aacaacaaac gaaatttcta aacttttaaa gttatcaggt
    28441 gctaataagg tttttgtatt gactctactt acaaaagcaa atgataatta tattatggaa
    28501 taatcttata tattgacaat tttagtttaa aatattaaaa tgaataagtg atatttaggt
    28561 ctgtggttga aagtccaagc cagtcgcagg caaagggatc cacgtaagtt aacactaaaa
    28621 attgggttaa tgatcatggt gcggcttaga agtaagacct accgataata aaatcgagag
    28681 agagtagtag tgcggcgaac ccaagcgaac cctccagtag gcgagtgtgg ggtcaaaaac
    28741 caggtcagct aaatatcata ttaaaagaga gctagcatac ctttatgtat agctcttttt
    28801 tatatataat aaatttaggt tgagtcataa agaggtgata tgtttgaata aaagacaaga
    28861 aaatttatta acaacattgc tattaaaaga agagtttata aatgttaata agattgccaa
    28921 tgattttgag tgttcagaaa ggacaataag aaatgattgc aaatatattg atgaatggtt
    28981 atctactttt tgtaatgctt atatcaaaag aaaacctaat attgggatta aatttagtgg
    29041 agatggaaca gacaaaatac tggtaaatca gaagttgcga ggtgaagtta aaagagtaaa
    29101 tagtgagctt cataagcaag ttgagatatt aaatttacta ctttgtaata ataaaaaagt
    29161 tactttaaat gatttatcta ataagttgta cataaataaa aatattgtca gagaagaaat
    29221 aagtaaatta tcagtagcat taaataatta taatttaaat atctcgacta aaaaaggcag
    29281 tggtatatat attcaagggg atgagaaaga cataagaata atgttagtat cattcttatt
    29341 taaatatata gataaataca gattaaacat agatgaaata gagtacttcc atatagtaga
    29401 tataataatt gtaaaaaaca taatgcttac tatagaggag gacatggata taagacttac
    29461 agatatatca ttcaaacaat tgatgctatt tttgcttata aatataatac gaataaggct
    29521 gggaaattct ttaaaagtat caaatactaa gaaagagctt aagctaaaaa tgcttatatt
    29581 ggatatagaa gatgaattga aatctaattt atccatagta ttaaattatg aagaaaaatt
    29641 gtttatagaa tctttaatat tgggtatgaa caaacaaata aatagtaata atattaagaa
    29701 atctttatat ctaaatgaag aattagcaag ttatacaaaa aaaattataa atttagtatc
    29761 agaagaatca ggaataaatt ttaataatga tatattactt tatgaacaat taatatgtca
    29821 tttgaatgtt acaatgcatc aaatgaaaag caatgtttac ttagaaaatc cacttttaga
    29881 taacataaaa actaaatttt gttttttatt tacagtaata tcaagttcaa tagaaattga
    29941 attaaaagga aaacaaataa cggaagatga aattggttat cttacacttc actttcaaac
    30001 ctctctagaa agaaaataca gcaaaaggga atcaaataaa aaggcaagta ttgtatgtcc
    30061 atttagtttt ggagtaagta tgctattaaa agtaaagata gaaaagagat ttgataatat
    30121 aaaaattatt gaaacattaa gagaggaaga tttaaaaaga gataacttca ataagactat
    30181 agattttata attgcatttc aagagtatga aaatatccaa aaaccaattt ttataacaac
    30241 accattattt actgatgagg atgagaataa acttaaagag ttcacaaaca aaataaaaga
    30301 aaaagacact tcatataaac ttatgaacag attaatgatg tctgattatt taataagaga
    30361 gttagaacat gatgatattt atgaagctat aacatattta actaatttat taattgaaaa
    30421 acattatgca gaaaaagagt atttacaatc tattataaca agagaaaagt catatccaac
    30481 caatgttgga aaaggaatat tattccctca tggagacatg aaatatataa aacaatctgt
    30541 tttatgtttt gcaaggttaa aaacaccaat aaaaattaga aatggaaagg atataaagat
    30601 tatacttttg ttagcatata aaaaagatga tgatagaaaa gtatttagag aattatttaa
    30661 agaaatatct aatttaacag aggatgaaaa tatgctagat attctaagta aatgtgacat
    30721 tgaaaaggta aaagatattc ttatataaaa ttcatagtga actatggata agcacaaaat
    30781 tttccatgtg atggaaaaag ttgtgcatgt ttttttgttt ttataagata ttatatgttt
    30841 gtaaggtata aataatctaa aagtagagaa gcaacttagg aggaaaaaat ggaagaaata
    30901 gttttaaaga ttataattca tgctggaaat gcaaaatcta tgctttatga agcacttgac
    30961 tatgcaaagg aaaacgattt taaaaaagca gatgaattaa ttgaaaatgc aaatgaagaa
    31021 attttaaaag cacataaagt acaaactgaa cttatacaaa aggaagctgg gggagataaa
    31081 tcagatatat ctattttatt gattcactct caagaccatt taatgacttg tatgagtgag
    31141 agaaacctta taaaagaaat gattatgtta agaaaagaaa ttcaaaaatt aaaataaaaa
    31201 aattaagggg gatttaaaaa atgaaaagaa aagtatattt attttgtagc tttggtatgt
    31261 caacaagttt acttgcagat aaaatgcaga aggtagcaga tgaacacaat ttaccaatag
    31321 aagtagaggc atttccgata gcagaaattg acaaaatagt tgaagaaaaa aatccagatt
    31381 gtatattatt aggaccacaa gttaaataca tgctaaagga gttaaaacca aagtttgaag
    31441 ctcaaggaaa acttatagat ataatcaatg aagttgatta tggaactatg aatggggaaa
    31501 aagtattaaa gcttgctata aagctaataa aatctaaaca agcgtagaat tatagtaaaa
    31561 aataatagga aatgagggtg gatagatgaa tagattggaa agaatactta tgccattggc
    31621 tgaaaaaata ggtaaaaata aattattaat tgcaattaga gatggttttt tagtatcatc
    31681 accattatta ataataggtt cattattttt attagtagca aattttccta taaaaggatg
    31741 gaatgaattt gtaggtcaaa tttttggtcc agattgggct gtaaaattgc aacaaccaac
    31801 tgtagcaaca tttgaagtaa tgactctact tgcagtttta gggattggat attcttatgc
    31861 aaagcaaata gatgtagacc caatagcatc agcagcagtt gcaatagttg ccttttttat
    31921 aataacacca tttgtaatac catatacacc agaaggaaca gaatcagttt acatggtaac
    31981 aggtatacca ctaggttgga tgggttctaa gggaatgttt gtaggtatga taacagcaat
    32041 aacctctgta aaattatttg ctgcagttgt aaaaaaagga tggacattga aaatgccaga
    32101 tggagttcct ccaactgtat caaaatcatt tgcagcatta ataccaagtg caatagttat
    32161 ggtagttttc tttttagtta agatagcttt tgaagctaca ccatatggaa gtatacatga
    32221 atttatattt aagtttttac aaatgccatt attaaaatta ggaaatagtt taggtgctat
    32281 ggcaatcgct tatatattct tacatttatt ctggttcttt ggaataaatg gaagtagtgt
    32341 tgttggggct gtgtataatc caatattaaa aattctatca gctgaaaact tagctgcttt
    32401 tcaagctggt tcaaaaatac caaacataat aacaggtcaa ttccaagata tgtttgcgac
    32461 atttggtgga gcaggtagta cactatcatt agtcatagct atgttattaa tatgtaaaag
    32521 taaacgtata aagtcaatgg gaaaactatc aattttacca ggaatatttg gtataaatga
    32581 gccattgata tttggtctac caataatgct taacccaata ctattgatac catttgcaat
    32641 agttccaaca ataaatataa taatagctta cttctgtatg tcagcaggat tagtgcctct
    32701 tacaaatgga gttcagttac cgtggacaac tccaattata ttctctggtt ttttaacaac
    32761 aggatggcaa ggtgcagtct tacaattagt acttcttata ctaggaatat ttatgtatat
    32821 accatttata aaaatgctag ataagcaata cttgagagaa gaaaatgaaa ctgttgaaga
    32881 ggaagatgat gatatatctt ttgatgattt agtattatag gaggaagatt atgaagaaaa
    32941 tagttatgat attggaccaa atacaagctg gagctggagg aaaagagaaa agtaatatac
    33001 ctcctgctgg aaaatcaagc ccattaggac caggtgtaat gatggagcaa tttttaaatg
    33061 aatctaaggt aatagctacc ttattttgtg gggatgaatt ttttgtaaat aatcaagaag
    33121 aagtaacgag taagatgata gctatggtaa aaaaattaaa ccctgatgta gtaatctgtg
    33181 gaccaagctt taattacgaa aacttttcta agatgtcagc aatactgtct aaaaatataa
    33241 atgataaaac agatatacca gcttttgcag ctatgtcaga agaaaatata gatgtgataa
    33301 acgaatataa aaatgacata tgtatagtta agactccaaa aaaaggtgga attggtctta
    33361 ctgattcgtt aaataacata tgtaaattgg caaaagcaat agcaaataaa gaagatataa
    33421 ctttgatgaa agaagaattt tgttattaat aagagtatta attattagca agtttaaata
    33481 ttatactatt tataataagc atacattagt aaaatctata taatttaagg aggggaattt
    33541 taacatgtgg ggaatgatag cgacatggag aatggcccta gaaggaataa ctgaggcatc
    33601 agaacattta gaaaaaggca tggaagcagg tgatgctgta gagcttgctg taagaagggt
    33661 tgaagactat ccattctata aatcggttgg atatggtgga cttccaaatg aaaattgtga
    33721 ggtagaactt gacgctgcat ttatggatgg taacacatta gatattggcg cagttgctgg
    33781 tataagagat tattctaatc ctgtcagcat agctaggaag ttaagttatg agaaggtaaa
    33841 taatttttta gttggaatag gtgctgaaga ttatgctcat aaaaatggat ttgaaagaaa
    33901 aaatatgttg actgatagag cgaagttaca ttataaaaag agaaaaaaag agactttaga
    33961 caaaggatta agcccatatg ctggtcatga tactgttggt atgatatctt tagacaaaac
    34021 tggaaaaatg tgtgtagcta catcaacaag tggattgttt atgaagaaaa gaggtagaat
    34081 aggagattct gcactatctg gttcaggatt ctatgttgat agtagtatag gaggagctac
    34141 agctactggt ttgggagaag atttaatgaa gggatgtata tcttatgaga tagttagact
    34201 tatgaaagaa gggaagcatc cacaagaagc atgtgatatt gcagtaaatg aacttgataa
    34261 acagcttatc aaaagaaggg gaaaagctgg tgatttatca ttagttgcca tgaataataa
    34321 aggtgaatgg ggagtagcta caaatatagc tgattttact ttttcagtag taactaaaga
    34381 agaatctcct actgtatata tttcaaatag agtagatgga aagactatac ataaggttat
    34441 atcaaatgag tggatggaag catatgaggc tagaataaaa gcaccaatag aagtaagtga
    34501 gtaaagtagt ggttacataa ttaaaataga gttttataat aaggagattt ttatgaatat
    34561 cataagtaat aaaatagatg agttaaaaga agatttatta agtgatatta tagatattgt
    34621 aaaaatacct agtgtcaaag gggagtcaga aaatggcttc ccttttggcg aaaaagtagg
    34681 ggaggcactt aataaagcat tagaaatatc agaaaaattg ggatttaagg ttagaaactt
    34741 ggataattat attggttatg cagagcatgg agatagtgat gattatgttt gtgtaattgg
    34801 acatgtagat gttgtacatg aaggagatgg ttggaagcat cagccttata agggagaaga
    34861 aactaatgga agaatttatg gacgaggagt actagacaat aaaggaccta taatgtctgc
    34921 cttatatgga ttatatgcta ttaaagaatt aaacttaaaa ttagataaga gagttagaat
    34981 aatatttggt acaaatgaag aaagtggatt tgaagatata ccatattatt tagaaaaaga
    35041 aaaagcacct attatgggat ttacaccaga ttgtaagtat cctgttgtat atggtgaaaa
    35101 aggcatggca aagattagaa taaaaagtaa aatcaattat gaagaagatg tatacctagg
    35161 ttttatagaa aatatgtctg aaaatgtgct tgttacatat aaagagctga atatagaaaa
    35221 tagtgatact atattagata taaaggtaaa atacgatttt agttataaat tgaaagatgt
    35281 attagatgaa ataaaagcta gttttccaaa tagtatcgat atagaggtaa tttctaattt
    35341 taatcctgta tattttgata aagagagtaa tcttgttaaa aagcttcagc tagcttatga
    35401 aagggttaca tcattagatg gaactcccgt aacaactaat ggaggtacgt atgcaaaagt
    35461 aatgccaaat atagttccgt ttggaccttc atttccagga caaaaaggaa tagctcataa
    35521 tcctgatgaa tacatggata tagaagatat aatattaaat gcaaagatat ttgcaaatgc
    35581 aatatatgaa ttagcaaagg agtagttatg ttagaaataa taggaatgtc agtagaagac
    35641 gctaaaatta tagaagattg tggtgcagat agaatagagt tagttagtgc tttaactgaa
    35701 ggtggattga caccaagttt tggtcttata gaaagtgttg ttaacagtgt aaagatacct
    35761 gtgaacgtaa tgataagaca tcatgcgaaa agttttgtat acagtaaaga agatataagt
    35821 ataatgcaaa aagatataag tgtggttaaa gagattggtg ctaatggagt tgtatttggt
    35881 gtattggata aaaacaacaa tatagatgag aaaaatctaa atgttttatt gaaatgttgt
    35941 gataatcttg atgttacatt tcatagagcc atagatgaat caaatacaat agatagtgtt
    36001 aaaattttga aggattatga taaaattacg aatatattaa catcaggtgg gaaaggaagt
    36061 atagttcata acatacaaat gataaaaaat atgatgctta gttctaatca cataaaaatt
    36121 cttttaggtg gaggtcttaa ttttaataat atagaaaaga taaaggaatt aactaaggca
    36181 agtaattttc attttggtac agcgattaga ataaataaca gtccttttga agatatagat
    36241 agacaaaagc ttaaacaact cgtaaatata atttcaagat agtatatgaa tataaaatac
    36301 ttagtttaaa taaagagagt aagttaatta taatttgggt atatgaatgt taataggtat
    36361 taaatatgaa attattgttg agtatgcttt ataactttta agtagtttta aatataaata
    36421 atgaaagaaa agatagatta tggaggtttt agagggttta tatttattaa aaaattataa
    36481 aggtatattg gcatataata cacataattt cctaaaatta ccatcttatg acatgaattc
    36541 acatattaat aaacaattaa tggagatttt tgtggataga aataggagta aaaatagctt
    36601 taaataaaca aaaacaagag ttattaacag ttttatccac attatccaca ggtgtttgta
    36661 ataatattaa tccacataag tatcaatgta actaaaaatg ataaataatt ctatcaattg
    36721 aatagaaaaa atcataaaag taaataataa aaagaggatt atgagagttc gtgtagaata
    36781 tattattaaa gtataaattt tcttatactg gcataattga agggagatgt atttatgaac
    36841 ataattatat ctggaaaaca aatcgaatta actgatgcaa taaaaaataa aatcgaaact
    36901 aaactaagta agttagataa ttacattcat ccagacactg atgtaaaagt tacagtaagt
    36961 gcgagaaaag caagacaaaa aatagaagta acaatagcta ctgtaaatgg tcctataatt
    37021 agagcagaag atatgcagga aaatttatac acagctatag atgttgtata tgataaatta
    37081 agtaaacaat taaaaaaata taaaaagaga ttacaagata aacataaaga caacaagagt
    37141 ataagattcc aagatgcaga gataaatcta gctgatgaac aagaggatta tggggatgaa
    37201 aatcaagaat tagtaattca aagacgtaag aaatttagtg ttaagccaat gagtgaagaa
    37261 gaagctgtat tacagatgga attaatagga catgattttt atatgttcaa gaacatagat
    37321 tcagatgaaa tagcagtagt ttataagcgt aataatggtg gatatggtat aatagaacat
    37381 gaataaagca atttagattt aatcatatta gctatcgata aataaattat cgatagcttt
    37441 ttaaattaat attaaaagta tagtttttat ggtaaaatga ataatagtac aataaagaac
    37501 gaggagagat gtaaaatatg agctttatgg ataatttatt caacatggca gataaaaaag
    37561 aattaaaaaa gttcaataaa actgttgata taatagattc attagaacct aaatttgaat
    37621 ctatggcaga ctcggaactt aaaaatatga caaatatatt taaagaaaga ttagcaaatg
    37681 gtgaaagtat agatgatata cttccagaag cttttgcagt agttagagaa gtttctaaga
    37741 gagtgttagg acttagacac tacagagttc aaatgattgg aggtatagta ctacatcaag
    37801 gaagaatagc agaaatgaaa acaggtgaag gtaaaacttt ggttgcaact gctcctgttt
    37861 atttgaatgc gcttactgga aaaggtgtac atgttgtaac agtaaatgat taccttgcaa
    37921 aacgtgatag agaccaaatg gcaaaaatct atgagttttt aggaatgagt gtaggcgtta
    37981 ttatacatgg tcaaaatcca aaagttagaa aagaacaata tgattgtgat ataacttatg
    38041 gtacaaataa tgaatatgga tttgactatc taaaggacaa tatggtaata cacaaagagc
    38101 aaagagttca aagaggatta aattatgcta tagtggatga ggttgactct atactaatag
    38161 atgaggctag aacaccactt atcatatctg gacctggaga caaatcaact cacttatatt
    38221 cagatgcaaa cacatttgtt ttaaccttaa aaccagatga ttatgaatta gaagaaaaag
    38281 ataaggctgt atctctaaca gcatcgggta tacaaaaagc agaagtgtat tttaatgttg
    38341 ataatataac agatatatct catacagaat tataccatca tataaatcaa gctttaagag
    38401 cacatgtaat aatgaagaaa gatgttgatt atgttgctaa agatggagaa atagtaatag
    38461 tagatgagtt cacaggtaga cttatgtttg gtagaagata ttcagaaggt ttacatcaag
    38521 caatagaggc taaagaaggt cttaaaatac aaagagaatc taaaacacta gctactgtaa
    38581 cattccaaaa ttactttaga atgtacaaaa aactttctgg tatgactggt acagcaaaaa
    38641 cagaagaaga agagtttaaa gcaatctaca aaatggatgt tttccaagta cctactaata
    38701 agcttatgat aagggaagac ttaccagatt gtgtatacaa aagtgaaata ggtaaattta
    38761 atgctgtagc acaagaaata attgaaaggc acaaagtcaa tcaaccaata cttgtaggta
    38821 cagtatcaat agaaaaatca gaattattat cacaaatact aaagaaaaag ggcataaagc
    38881 acgaggtatt aaatgctaag catcatgata aagaggcaga aataatagca caagctggta
    38941 gacttggagc tgttacaata gctactaata tggctggtcg tggtacagat atagttctag
    39001 gtggaaatcc agacttttta actaagagag aaatgagaag aaatggattt aaagaagaaa
    39061 tagtaaatag agtagatact ccaatagaag gtatacctgt aaaaggtaat gaaattctat
    39121 ttgaagctag agaagagtat gaaaaactat ttgaaaagtt taagcaacaa acacaagaag
    39181 aacaaaaaca agttgtagaa gcaggtggac ttgctataat aggtacagaa agacacgaat
    39241 ctcgaagaat agataaccag ttgagaggtc gtgctggacg tcaaggtgac ccaggtagtt
    39301 caagattcta tataggtctt gatgatgacc ttatgagatt gtttggtagt gatagaatat
    39361 ctggtattgt agataaaata ggtcttgaag aagatatgcc gatagaacat agaatattat
    39421 ctaagtctat tgaaggagca caaaagaaag tcgaaggtaa aaactttgga ataagaaagc
    39481 atgtacttca atatgatgat gttatgaata aacaaagaga aataatatat gcagagagaa
    39541 aacgtgtatt agaaggtgaa gatttacaag aacaaataca atcaatgact cattctataa
    39601 tagaagaagc agttactctt tatacacaag ataaaggatt tgatgaagaa ggattcaaag
    39661 aacatatgta taatctgttc ttgccaaaag gtagcataga aataccagaa atagaaaaac
    39721 ttaatccagt tgaaataaca gaaaaagttt atgaaatagc tatgaagata tatacttcaa
    39781 aagaagaaca agttggctat gagagaatga gagaagttga gagagtaatc ttacttcaag
    39841 ctgttgataa ccattggata gaccatatag atgctatgga ccaattacgc caaggtattg
    39901 gtcttcgtgc tgtaggtcag caagacccag ttattgctta taaaatggaa ggttttgata
    39961 tgtttgatga aatgaataaa catatcaaag aagatactgt aagatattta tttaatataa
    40021 caatagaaac tccagtggaa agaaaagcag ttgtagatgt tgaaaatcta tcttctccat
    40081 cagatggaac acttccaaca agtaaaactg ttaaaaaaga tgaaaaggtt ggaagaaatg
    40141 acttatgccc ttgtggaagt ggtaaaaaat ataaaaactg ttgtggaaga taatctcgga
    40201 ggattaaatg ttaaagttac aagagtatag acatagtatg gagcagatgg cttcaaattt
    40261 agaagaattg agggtttctc tttgacatag cttcattgat gaaaaatata caaattaatg
    40321 aagaaaagat gaatcaacaa gacttttgga atgataatga agtcgctcaa agagtacttc
    40381 aagaaaataa atctttaaaa gagacattag aagaatatga aagcttaaaa agcttattag
    40441 aagatataga agtattaatt gaaataggtt tagaagaaga tgatgattct gtagaaagag
    40501 atatagaaaa gtccatagaa tcaatggaag aaaaattatc tgaaatgaaa ataaagactc
    40561 ttctaaatgg agagtatgat aaaaataatg ctatattatc tataaatgct ggtactggtg
    40621 gcttagatgc tcaagattgg gctcaaatgc ttttgagaat gtatataaga tggtcagaaa
    40681 gtaagggtta taaagttaag cttttagata taatatcaga ccctgaagca gggataaaga
    40741 cagctacaat tcttgtagaa ggaacaaatg cttatgggta tttaaagagt gaaaaaggag
    40801 ttcatagatt agtgagaata tctccatttg acccatcagg aaaaagacat acttcatttg
    40861 catctataga tgtaacacca gagttagatg aaaatataga agtagaaatt aatccatcag
    40921 atttaaagat agacacatat agagcttctg gagctggagg gcaacatgta aatacgactg
    40981 attcagcagt tagaataaca catatcccta ctggtgtagt agttcagtgc caaaatgaaa
    41041 ggtctcagca tctaaataag gacagagcta tgagactttt aatggcaaaa ttgatagaat
    41101 taaaagagtt agaacaaaag gaaaaaatag aagatataca aggcaaatac tcacaaataa
    41161 cttggggtag tcaaattagg tcatatgttt ttcaaccata taaattggtt aaggaccata
    41221 gaacaaatgc tgagtttgga aatgtagata gtgtaatgaa tggaaatata gacttgttta
    41281 ttaatgaata cttaaaaatg aataaaatag tttaataaat atgcactgta attaagatat
    41341 atgtataaga aggttagtgc ttaatatgca cttacagcac ttaggctgag gacgataacc
    41401 ctcagccttc gttctgtttt gttatactta tgaaaaacta acattaggag tgaataaatt
    41461 ggatataaat caaatcttaa aaaaagagtt taatcttaga gatgaacaaa taaataatac
    41521 attaaaactt attgatgaag gaaatacaat accatttata gctagatata gaaaagaaat
    41581 gactggcgaa atgagtgatg ttacactaag agaattttat gaaaaattaa tgtatttgag
    41641 aaatcttcaa agtagaaaag atgatgtagt tagactaata gatgaacaag ggaaattaac
    41701 agatgaaata acacaaaata tagaaaaagc aaaaacatta caagaagtag aagatatata
    41761 tgctccatat aaacaaaaga aaagaactag agcaacaata gcaaaagaaa aaggattaga
    41821 aaatttagca ttgtcaatac tagagaataa tttagataat atagaaatag aggcaaagaa
    41881 ttatcttgat gaagagaaag aagttctttc tattgaagat gctctaaaag gtgctagaga
    41941 tataattgca gaactagtct cagatgatgc taagattaga aagtatataa gagaattagc
    42001 tttaagagaa ggtatgatag ttagcaaaag tgctactgat gagaaatcgg tttatgatat
    42061 gtattatgat tatagcgaag cagtaaaaag tatggctcca catagagttt tggcaataaa
    42121 cagaggagaa aaagaaagct tcctaaaggt taagttggaa ataaataatg ataaagtttt
    42181 aaattacata ataaacgaat atgtaaatga taaaaatttc aaaaataaag aagaaatcgt
    42241 aagttcaata gaagattctt ataaaagatt aattttccca tcaatagaaa gagaaataag
    42301 aaatcattta acagaaatag ctcaagaaag agctataagt gtatttggaa agaatgttaa
    42361 aagtttattg cttcaaccac cagttaaaga caaagtagtt atgggatttg accctgcatt
    42421 tagaactgga tgtaaaatag ctgtagtaga taaaaatggt aaactactag attatacaac
    42481 agtatatcca acagaccctc aaaatgatgt agagggagca aagaaagttt taaaaggatt
    42541 gattgaaaaa tacgatatag atataatttc aattggaaat ggtactgcat ctagagaatc
    42601 agaaactttt gtatcagaaa tgataaaaga aatagatagc gaagtgcagt atgtgatagt
    42661 tagtgaagca ggagcatctg tttattcagc atctgaactt gcaaatgagg aacatccaga
    42721 tataaatgta tcaataagag gagctatatc tatagctaga agattacaag acccattagc
    42781 agagcttgta aaaatagacc ctaaaagtat tggtgttggt caatatcagc atgatttaaa
    42841 caaaaagaga ttagaagaag tactagatgg agttgttgaa gattctgtaa atagtgttgg
    42901 agtagattta aatactgcat catactccct actagaacat gttgcaggaa taagtaaagc
    42961 tatagcaaaa aatataatag catatagaga agaaaatgga gattttacgt caagagcaca
    43021 attgaaaaaa gtaaaaagac taggacctca agcatttact caatgtgctg gatttatgag
    43081 aatcttagag ggtaaaaatc cactagataa tacaggtgtg catcctgaaa gttatgatat
    43141 atgtaaaaaa atgattgaga taattggata ttctttagat gatgtaaaga ataagaatat
    43201 aggtgaaata gatgaaaaaa taaaagaaat tggcttgagg gaattaagtg aaaaactgga
    43261 agtaggacaa gttacattaa aagatattat agctgaaatc aaaaaaccag gaagagaccc
    43321 aagagaagaa ggtataaaac ctatacttag aactgatgtc ttaaaaattg aagatataca
    43381 agagggtatg actttaaaag gtacaataag aaatgttgta gactttggtg catttgtaga
    43441 tattggaata aaaaatgacg gattagttca taaatcagaa atgagtaata gttttgtgaa
    43501 agaccctatg agtattgtta cagtaggtga tatagtagat gtaaaagtca ttggaattga
    43561 cttaaacaaa aaaagagttg ccttatcaat gaaaaaatag ataagtttat gtatggttat
    43621 agtacttaga ttctatattt gtaaatgaga ttactcgagt gtataaatgt taaaaatttg
    43681 taaaagtata tagtaagaaa atatattaaa ataagaacga tagtcttgaa aatcaggagg
    43741 aaaatgaatg atttttataa aaaatggtaa aataaatacc ataacaaatg ggataattca
    43801 tggagatata cttatagatg aaggaaaaat aatagaaatt ggagaagatt tgatagctcc
    43861 tttagatgta gaggtaatag atgctagtaa taaacttgtg tttcctggat ttatagatgc
    43921 tcatactcac ttaggcttat gggaagatgg tatagggttt gaaggagcag atggaaatga
    43981 agagactgac ccaataacac cacaattaaa tcctatagat ggaattaatc caatggatag
    44041 aacttttaaa gaagcttttg aaggtggaat aacttctgtt tgtacaaccc ctggaagtgc
    44101 aaatgttatg ggtggtcaat gtatagctat aaagacatgt ggaaaaagaa ttgataaaat
    44161 ggtaataaaa aatccagttg catctaaaat tgcttttgga gaaaatccaa agagctgtta
    44221 tggtcaggat gataaatctc ctcaaactag aatggctata gctgctttac ttagagaaaa
    44281 cctaaaaaaa gcagaagaat atttagagga tattgatatg tatgagagtc atgatgatga
    44341 agactgtgaa aaacctgaat atgatataaa aatggaaagt ttaataccag ttttaagaag
    44401 agaaattcct tttaaggcac atgctcatag agcagatgat atgtttacag caataagaat
    44461 tgcaaaagaa tttaatttaa agcttacatt agaccattgt acagaaggtc atcttattgt
    44521 agatgaatta gtggaagaag ggtttcctgt aatagtaggg ccatctttgt cagaaaggtc
    44581 taaatttgag cttagaaatt tgacatttaa tacagcagga atactttcaa atgcaggtct
    44641 tgatgtatgt ataatgacag accatccagt aataccagtt caatatcttc caatatgtgc
    44701 aggtattgca gtaaaacatg gtatgaaaga agaaaaagca atagaatcaa ttacaataaa
    44761 tccagctaag actttaggaa tagaagatag agtaggctct atagaagttg gtaaagatgc
    44821 agacctagta atttgggata attctccact agagattcaa agtaatgtac tttacactat
    44881 aataaatggc aaagtagtgt atgagaaaaa ataacttgac aattattaaa aaattaacta
    44941 atataagagt gtaaggaaaa ttaaaaaatc aaagaagatc ttcggggcag ggtgaaattc
    45001 cctaccggcg gtatagcccg cgaactactt aggtggttga tttggtgaga ttccaaagcc
    45061 gacagtaaag tctggatgag agaagatatt tatggaagat aaataagttt attttagttt
    45121 gtttaaacta tatccataaa aactcgaaga tagggtcttc gagttttttg tttttcctaa
    45181 aaaatataaa catattgatt agggggaaaa taattatgca aaacacagca aaaagaggca
    45241 atatgatttc aacaagaact ttagtagtaa tgtcaatttt atctgcaata tcttatttat
    45301 taatgtttat tcaagcacca ataccaggta tatttccaga tttcttaaaa attgacttat
    45361 cagatattcc agcaatattc ggaggaatgt ctctaggacc attagttgga tttggaatag
    45421 ttgtagtaaa aaatgtgtta caagcaataa cagcaacaac aactggagga ataggagaat
    45481 ttgcgaatat attaattggt ggttcttatg taatgatact ttgttattca tataagagaa
    45541 gtggagattt aaaaggtgta ctgattggtt ttgtattagg aacaatatct atgactataa
    45601 ttggttcatt agtaaattat tttgtaatgt tgccacttta tggtcaactt atgggactag
    45661 atgctataat aggtttaggt tcagctataa atcctcaagt tcatgattta ttcacttttg
    45721 taatttggat gatagctcca tttaatgtgc tgaaggctgt tataatatct ttagtaacat
    45781 tgccacttta taaaaaaatg ggaaatataa taaagaaata attagacaag aaaatataaa
    45841 attaaatgta ttgaatagcc ataatttatt tataacttca gtcctatatt gtgattgata
    45901 tattaaatat attatggctt tattaattta tcaaaaaatg tatataaaat aagaaatatt
    45961 tagacaaatt taaattttaa aataaaggaa gaattaaaac gattaactat taaaatatga
    46021 aaaaggtatc tacaatatac agagcgaatt tataataaac aaaaaataaa gttattatta
    46081 aaaaactata aagattagta atcaaatttt taataataac taatttaata atgatgggag
    46141 tgtatattca tgaacttatc taaaaagata aaaaaattat ttttagatga taaagggtat
    46201 tattttaata gtaattggaa agatattcat attggtattt ataatacaaa attaggagat
    46261 tctttaaagt atatcactaa tgaatatatt gaaaatctgg aaagggtaaa atatgactat
    46321 cgtgaattaa aaaatataga aaatcaaact gatggtatgt gtattttagc aataaggcag
    46381 aattacaagg cattagagta tgtaaaaaat caaaccgaag aattatgttt agaagcaata
    46441 aagtataatt ataaagcact tgaatatgta aaagagcaaa cagaatactt gtgtcttgaa
    46501 gctataaaaa aagattgtaa tgcacttaag tatgtacgaa ataaaacaga agggcttatt
    46561 ataaaagcaa taagtcattc ttccaatata gatgttgtaa gtatactaaa ggctttagag
    46621 actcaaacaa gaaggatatg tttagaagca attaaaaaag atggcaggtg tcttgcatac
    46681 gttagagaac agagtgaaga attatgtata gaggccatta agcaaaatta taaagcatta
    46741 aaatatgtaa aaaatcaaac ggaaaaaatg tgtatagaat ccgtaagaca aaatggtatg
    46801 gcattacaat atgtaaataa acaaactgat aaaatatgta tagaagctgt caaacaagat
    46861 ggaagaagtc tacaatttgt caacaataag acagaagaaa tatgtataaa tgctataaga
    46921 tatttaaata aaaaatataa tattaaagat gtactaagtt acatagataa gtatacagaa
    46981 gatatatgta tagagattgt aagacaaaat ggaaaaatgc ttatgtatat aaaaaatcaa
    47041 acagaaaaaa tgtgtattga agcagtaaaa gagaactata agtctcttaa gtatgtaaaa
    47101 gagcaatctg agagaatatg taaagaagca ttgaagcaaa accataaagc aaaagagtat
    47161 gtaaaaattg ctattgatga ttgtatataa ggtgtagata cagccatcaa tagtgaaaga
    47221 taaaaaaaga taaagacaag tactttataa taatctaggc ttatactata attaattaag
    47281 cagtgatata aattcacatg acgattatat caaaatggag atgaattgat ggcaaaaata
    47341 tatttagaaa atgaaaataa aactagagaa ataggatata aattaggtaa acttttaaaa
    47401 gaaggcagtg ttatctgttt agtaggagat ttaggagctg gtaaaactac aatgacacaa
    47461 agcttggcag attcattagg gatagaagat tatataacaa gtcctacttt tactataata
    47521 aatgaatatg aaggaaaaat acctttgtat cattttgatg tttatagaat aggtagtagt
    47581 gacgaaatgt atgatattgg ttatgatgaa tatgtaaatt caaatggaat ctgtataata
    47641 gaatgggcta atctaataga agatatactt ccaaaagaat atttgaatat agaattgaga
    47701 tataaagatg aaggaagaga aatgatatta actccaaaag gagagtttta taaagagata
    47761 gttgaggagt tgattaaata atgaaaatac taggtatgga tacgtcttct atggcagcaa
    47821 gtgtagcagt tgttgaagat gataacttaa tatgtgagtt tacagtaaac aacaaaaaaa
    47881 ctcattcaca aaagcttatg ccaatgatag aaaatatgtt gagtatgagt gatttaagta
    47941 taaaagatat ggatttatta gctgtatgta taggtccagg ttcgtttaca ggacttagaa
    48001 taggtatggc tacagtaaaa gctatggccc atgtaaataa tataccaata atagcagtaa
    48061 attctttgga atctctagca aataacataa atttctgtga tagaaagata tgttgtatat
    48121 tagatgcgca gaaaaatcaa gtttattcag ctaaatacaa gtttgaaaat ggagagatga
    48181 tagaattaga tggtgttgat gttgtagatt ttgatgcttt agtagatgaa attgtatcaa
    48241 ctaatgaaga atttataata gttggagaag ctgtatacaa atataaagac aagttagaga
    48301 atataaaaaa tataaaaata ccttcaccaa ctaataatgt atctaacgca ggaagcttat
    48361 gctctttagc attaaataaa tataataaaa atatagatgt acatacttgt tatacgataa
    48421 atcctatgta tatcagaaaa tctcaagctg aagtacaata tgatgaaaaa atgaagaggc
    48481 taaataatgg aagataatac aaaactaata gtagatgata taaaaataga agaaatgact
    48541 acagaagata tagatgaagt ttttgaagta gaaaaaaatt gttttgaaga ttattggtca
    48601 aaagagtctt ttagaaaaga gttgtctaat gaagtagcaa ggtatatagt agctaagtta
    48661 aatggaaaaa ttgtcggata tgtgggaatt tggcttatac ttgatgaagg gcatataaat
    48721 aatgtggctg ttcatagtga ctatagaggg aaaaaaatag gggacaagtt gataaaaggc
    48781 atagttgatt tatgtaaaga taataatatt gcatctatga cattagaagt tagagcatca
    48841 aataaaatag cacaaaattt atatagaaaa tatggattta aaatgggtgg aataagaaaa
    48901 gaatactaca gtgataataa agaagatgca attataatgt ggaaccaatt aaaagaggtg
    48961 tagagtttat gagtgatata ataacattag ctatagagag tagttgtgac gaaacagctg
    49021 catcagtttt aaaaaatggt agagaagtac tttcaaacat aatctctact caaatcgaga
    49081 cacataaaaa atttggtggt gtagttccag aagtggcctc aagaaaacat gtggaaaata
    49141 ttgatatagt tgttcaagaa gctttagaca acgcaaatat aggttttaat gatatagacc
    49201 atatcgcagt tacatatgga cctgggctag taggtgcttt attggttggt ctatcttatg
    49261 ctaaagcact tgcatatact ttgaatattc cacttgtagg agtaaatcat atagaagggc
    49321 atctaagtgc aaactatata gagcataagg atttaaaacc tccttttata acattaatag
    49381 tatctggagg tcatactcac ttggttgaag taaaagatta tggcaagtat gaaattttag
    49441 gaaaaacaag agatgatgca tctggagaag catttgataa gatttcaaga gctatgaatt
    49501 taggctatcc aggaggtcct attattgata atctggccaa gaatggaaat aaacatgcta
    49561 tagaatttcc aagagcctat ttagaagaag atagctatga ttttagtttt agtggattaa
    49621 aatcttctgt attaaattat ctaaatggaa aaagaatgaa aaatgaagaa atagtagttg
    49681 aagatgtagc agcatctttc caagaggctg tagtagaggt tttatctact aaagcactaa
    49741 aagcagtaaa agacaaagga tacaatatca taactctttc tggtggggtt gcttctaatt
    49801 cggggcttag agctaaaata acagagcttg ctaaagacaa tggtattact gttaagtatc
    49861 ctcctctaat tttatgcaca gataatgcag ctatgatagg gtgtgcagga tattataatt
    49921 ttataaacgg gaaaacgcat gatatgagtt taaatgcagt tccaaattta aagataaatc
    49981 agtagagtta gatgaatttg taaatataaa agtattgttt caaaaaagta agtagaagtg
    50041 aaattaaata taataaaaat aaatatagta tatattaaaa cttgaagtaa aactatttat
    50101 aatctttata ttccaatgaa ttgcaacaaa ttttaggata tacagattgt ctttggctta
    50161 gatttgcttc aagtttaatt ttttctatag aaagattatt ttaaaaagtg ggtaatatac
    50221 cctttttttt cattcttaaa aagttttata ctaattatag aaagattaag gaggggaaga
    50281 aatgagtcaa agtaaagaag acaaaataag aagtattttg gaagcaaaaa atattaaatc
    50341 aaattttcaa aataaagaaa atttaagtga atttaatgaa aaaaaagcaa gtaaaagagc
    50401 agaagactta ttagatgtat attataatac attatctact gctgatatgg aatttccata
    50461 ttggtataat agagaatata gaaaatcaga tggtgatata ccagtagtta gaagagctaa
    50521 agctcttaaa gctgcttttt cacatatgac accaaatata atacctggtg agaaaatagt
    50581 aatgcaaaag acacgccatt atagaggttc ttttccaatg ccatgggtaa gtgaaagttt
    50641 ctttgttgct caaggagaac aaatgagaga agaggcaaag aaattagcca gtaacacagc
    50701 tgatgaactt acaaaatttg ggtctggtgg aggaaatgtt actgaaagtt ttggaaatgt
    50761 cgtttcaata gctggtaaat tcggaatgag aaaagaagaa gtacctgtac ttgtaaaaat
    50821 ggcaaaggaa tgggttggaa agtctgttga agatttaggt tttcactatg aaaaaatgat
    50881 gccagattat gatttaaaag aaaacctaat gagtacactt atatgcatgt ttgattcagg
    50941 gtatacactt cctcaaggta gagaagttat aaattatttt tatcctttaa attatggatt
    51001 agatggaatt atagaaatgg caaaagaatg taaaaaggca gttgcaggaa atgcatctgg
    51061 agatgggctt attggtatgg accgtctata tttttatgag gctgttattc aagttattga
    51121 aggattacaa acttggattt taaattatgc aaaacatgca aaatatttag aaagtataga
    51181 gacagattta gaagctaaaa aagaatactc agatttagtg gagatattag aacatattgc
    51241 acataaacaa cctcgtacat ttagggaagc tcttcagttg acttatacaa ttcatatagc
    51301 atcagtaaat gaggatgcta tatctggtat gtctatagga cgttttggtc aaattttata
    51361 tccttggtat gaacaagata tagaaaaagg actaattaca aaagaagagg ttatcgaatt
    51421 attagagctt tatagaataa aaatcacttg tattgactgt tttgcttcag cgggcgtaaa
    51481 tggaggagta ctatcaggca atacatttaa tactttatct ataggtggat taaaagaaga
    51541 tggttctaca ggagctaatg aactagaaga gttattatta gaagcaagta tgagatgtag
    51601 aactcctcaa cctagtttaa ctatgctata tgatgaaaag cttccagaag atttcttaat
    51661 gaaagctgct gaatgtacaa agcttggttc tggttatcca gcatgggtaa acaactcaaa
    51721 tggaacaaca tttatgatga aacaatttgc tgatgaaggt atgactgttg aagaagcaag
    51781 agcatttgca ttaggtggat gtttggaaac gtctccaggg tgttggaaac agttaacttt
    51841 aaacggaaaa acatactcta ttgcaggtgg agcaggtcaa tctgctggct ctggagttca
    51901 ctttatagct aatccaaaaa ttttagaact tgttcttatg aatggtaaag actatcgtat
    51961 gaatatacaa gtatttgagc ctcataataa gccattagat acttatgaag aagtcataga
    52021 agtatttaaa gattattata aacaagcaat aaatgtttta gaaagagcaa ataacattga
    52081 gttagatata tggagaaaat ttgatacttc tataataaat tcactactaa agccagactg
    52141 tttagacaaa ggtcaacata taggaaatat gggatatcgt tataatgcaa cattaaacgt
    52201 agaaacttgt ggtactgtta ctatggtcaa ttcatttgca gcacttaaga aacttgtata
    52261 tgatgacaaa gcatttacaa tagaggaaat gaaggatgcc atattaaata attttggatt
    52321 taaagatgca ttagaagtag gaaattattc tatggcagac caagtaaaag tagataagac
    52381 tggtaaatat gatgctattt ataaggcctg tcttgatgca cctaaatatg gaaataatga
    52441 tttgtatgca gataatattc ttaaaaacta tgaggtatgg ttatcaaaag tatgtgaaga
    52501 agcacaatct ttatatgcta agaagatgta cccttgccaa atatctgttt ctacacatgg
    52561 gccacaggga gctgctacct tggctactcc agatggtaga ctaagtggaa caacatattc
    52621 agatggttca gtctctgcat atgcaggaac agataaaaat ggagtatatg cattatttga
    52681 atctgcaact atttgggacc aagcagtagt tcaaaattct cagatgaatt taaaacttca
    52741 tccaactact ataaaaggac aacaaggaac taaaaaatta ttagatttaa caagaagtta
    52801 tttaagaaaa ggtgggttcc atattcaata taatgttgta gattcagaaa cattaaaaga
    52861 tgcacaaaaa aatcctgaca attatcgtca attaatggta cgtgttgctg ggtttactca
    52921 atattggtgt gaattaggta aaccaataca agatgaagta attgctagaa cagagtatga
    52981 aggggtgtaa aatatgagaa agcatagtga ttgtatgaat ttttgtgcag tagatgcaac
    53041 caaaggaatt tgtagattat caaaacaaat gattaattta gatgatgcag catgtccaga
    53101 gataaaagta atgccaaaat gtaaaaattg taaaaatttt gttgaagcta atgatgaagg
    53161 tataggcaaa tgtgttggcc tagagaaaga agactgggta tattcaacat tgaatgcaat
    53221 tacttgtgaa ggacatgtgt ttaatgagta gtcaaaagca attagaaggc atgatttttg
    53281 atgtacaaag cttttcagtt catgatggtc caggttgtag aacaactgta tttttaaatg
    53341 gatgtccact gagttgtaaa tggtgtgcaa atccagaaag ttggactgta agaccacata
    53401 tgatgtttag tgaattatct tgtcaatatg aaaatggatg tactgtatgt catggtaagt
    53461 gtaaaaatgg tgcattgagc tttaatcttg ataataagcc agttatagat tggaacatct
    53521 gtaaggactg tgaaagtttt gaatgcgtca actcatgtta ttataatgcg tttaaattat
    53581 gtgcaaaacc ttacactgta gatgaacttg tgcaggtaat taaacgtgat tctaacaatt
    53641 ggagaagtaa tggaggagta acatttagtg gaggtgagcc actacttcag catgaatttt
    53701 tacatgaagt attattaaag tgtcatgagg taaatataca cactgccatt gaaacgagtg
    53761 catgtgtatc aaatgaagtt tttaataaaa tatttaacga tattgatttt gcatttattg
    53821 atataaagca tatggataga gaaaaacaca aagaacaaac aggtgtgtat aatgatttaa
    53881 tattagaaaa tatatcaaac cttgcaaatt ctgattggaa tggaagatta gtacttagag
    53941 taccagttat ctctgggttt aatgatagtg ttgaaaatat aagtgatatt atatctttta
    54001 tgcacaaaaa taatttggta gaaattaatc tattaccatt tcacagatta ggagaatcaa
    54061 aatggattca attaggcaag gaatatgagt attctgataa gggtgatgtt gatgaaggtc
    54121 atcttgaaga attacaagat atatttttgg ataatggtat agcttgttat gttggtcatg
    54181 agacagcttt ctaaaattaa atacaagttt taattaaaaa aaggatgtta cactaaaagc
    54241 tagagttaca tcctttttta tgtggttttt atgtagaaat aattaagtaa agttttatat
    54301 gttttatata ttgtttatat tgctttatgt ccataaatat tgctttaaat atactttata
    54361 tattttttat agtttaaatt acagttagag aatatattac gtttacttca ttgaagcaga
    54421 agttttgtgg taaaatacta ctatgaaaaa atttaataga atatatttta gaaacaacta
    54481 aaaataatag ttaggaggaa gacatctata tgaacaaatc atggagcaac ttgattatta
    54541 agaataaaga caaaaaagta cgttcagggt ggattattat agctgttatg gctacctttt
    54601 acatacttca gtattattta agcatgatac ttgtggaaat aataagaaaa atcctggttg
    54661 ctacaggtga cattaattta aaaacaaact atttttcaga atatgctaat tggttaaatg
    54721 atgttgggtt acagattgta tttcaaattc taacagattc acttatgatt attattccta
    54781 taattgtatg gagatttatt atgaaaaatc ctattagtga aatggggtta cattcttata
    54841 gaattaagaa aaaagaagga tatgtaggaa tgttattagg aatatttaat tgtacagtaa
    54901 tctttattat aacaataaca attggtggtg gtcatgttac ttcatgggta ccaaaaattt
    54961 cacctttgac agtttcttgg atacttgtct ttattttagt tgcttttgca gaagaaattt
    55021 taaatcgtgg tttttttatg gcagttttac gaagatgtaa aaatatttat tttataatga
    55081 ttgttccatc tgttattttt gggttgattc atatatggaa tcctgatgtt acttttttgt
    55141 ctgtaattaa tattataatt attgggattc ttttttcata tatgtttata aagtcgtcga
    55201 atatatggat gtgtataggt tatcatttta catggaatgt atttcagggg attatatatg
    55261 gtatgcctgt aagtggactt caggttccag ggattataac tacacaaatc actcatggta
    55321 atctattaaa tggagggatg tttggtattg aaggtggaat tttgactact tttgttaatc
    55381 tacttagctt tatatttgta tggtattact atagagattc taagtatgat tttgttagtg
    55441 ataaagtaaa tgtgaccaat atcaagaatt agttgattat aataaatttt aataatatct
    55501 tctaagctta aagtattctg taggattgtt ggaaatttgc aaaaatataa aaataacttg
    55561 gatattctat ttactccaag ttatttttat attcttttgt aaatagaaat ggaacataaa
    55621 aaattaaaac aaccatagat actattagta tatcatggta agtgatagtt gattctttag
    55681 aatttgtgat aagaaaagca ctattattta aaacatgaat tatagcacaa aaccagatat
    55741 tcttagtttt tatataaaga tatcctaaaa atattgaaat tccaactata tgtattgaac
    55801 gtaatattat tcctaatatt ggcgcttcag gtgtatataa tgtaaatatt agtggtaagt
    55861 gccacaagct ccaacacata cctaatatta taactcctaa ctttttacca aatttatcaa
    55921 aaaaaatatt ctgtaaaaaa cctctccagg catattcttc actaaaaaaa atataaatag
    55981 tagttaatga tgttattgga gtaaatataa attttatgat accactataa ttaggttgag
    56041 ccccttgtag tattagtata aatgatgttg gaacaattac agaaatcata aagtaaataa
    56101 ttaataaaga acctagttta atatttttta caggatataa atttttttta tttgatgaat
    56161 atattataat tgataagcta cttataaaag ttaatattag gtttataatt ataaattcat
    56221 tattatttat tagatttaat aacttaagaa caattaataa tgaataaata agaaaaaata
    56281 atatgattag tgaataaaat tcatacatat cattatttaa tccttcagta taaaactttg
    56341 caatagcaac tgaagataga ggtaatatca tcatgaatga tgcaaagttt tctggatcaa
    56401 taaatttatt ataatataac agtaaaccta atgaataagt taaaccaaag tttataaaga
    56461 aaaagataat aatttgtatt ttttttcttt ttatttcatt tttaataaat actgggttta
    56521 gaatatttat ccatattaat tttaagttca ttaatttaat actcctttac aatatagatt
    56581 cttaactaaa ttaaaatatt ttattgaata ttataaattc atgacagtca atattattga
    56641 aaagtaactt ataaaattat atataaataa taaaattaat tttactatct acccatatat
    56701 ttagttatat tgcaggcaga atgtggttta acataaccaa aaggacaata aaaaatattt
    56761 ttctatattt ttattatctt tttgtaaaag atttattatt tattgcatta aattaatagg
    56821 cagtagaggc atagttgata aaattaatga agaaattaaa cttatgaata taactttatt
    56881 attgagtttt aatattacat ttattattct ctttgatttt aatattttat attt
//
LOCUS       DAEPXW010000012        54910 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.012, whole genome shotgun sequence.
ACCESSION   DAEPXW010000012 DAEPXW010000000
VERSION     DAEPXW010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54910
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.012"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            150..824
                     /locus_tag="KRM55_000732"
     CDS             150..824
                     /locus_tag="KRM55_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1592989.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            812..1972
                     /locus_tag="KRM55_000733"
     CDS             812..1972
                     /locus_tag="KRM55_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1592990.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKNQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            2189..2716
                     /locus_tag="KRM55_000734"
     CDS             2189..2716
                     /locus_tag="KRM55_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBH1592991.1"
                     /translation="MKSFANNITFSRIVFALLMLSFTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFSVTILVTVGKNIALPMYLWWCIIAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            3002..3670
                     /locus_tag="KRM55_000735"
     CDS             3002..3670
                     /locus_tag="KRM55_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1592992.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKGYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            3673..6141
                     /locus_tag="KRM55_000736"
     CDS             3673..6141
                     /locus_tag="KRM55_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1592993.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYTLSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSLISALPSAIYASHVSPKIAMAGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITNSILEDFK
                     NGSICFIKNPIAISTPGVKTRYTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNRSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLTC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(6381..7805)
                     /locus_tag="KRM55_000737"
     CDS             complement(6381..7805)
                     /locus_tag="KRM55_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1592994.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(7824..8516)
                     /locus_tag="KRM55_000738"
     CDS             complement(7824..8516)
                     /locus_tag="KRM55_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1592995.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(8568..9347)
                     /locus_tag="KRM55_000739"
     CDS             complement(8568..9347)
                     /locus_tag="KRM55_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH1592996.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            complement(9344..10114)
                     /locus_tag="KRM55_000740"
     CDS             complement(9344..10114)
                     /locus_tag="KRM55_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH1592997.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(10111..10815)
                     /locus_tag="KRM55_000741"
     CDS             complement(10111..10815)
                     /locus_tag="KRM55_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH1592998.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(11051..11563)
                     /locus_tag="KRM55_000742"
     CDS             complement(11051..11563)
                     /locus_tag="KRM55_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1592999.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMDFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            11889..12146
                     /locus_tag="KRM55_000743"
     CDS             11889..12146
                     /locus_tag="KRM55_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593000.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            12289..12915
                     /locus_tag="KRM55_000744"
     CDS             12289..12915
                     /locus_tag="KRM55_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593001.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIEVSSINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(13161..13940)
                     /locus_tag="KRM55_000745"
     CDS             complement(13161..13940)
                     /locus_tag="KRM55_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH1593002.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(14008..14469)
                     /locus_tag="KRM55_000746"
     CDS             complement(14008..14469)
                     /locus_tag="KRM55_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1593003.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(14445..15122)
                     /locus_tag="KRM55_000747"
     CDS             complement(14445..15122)
                     /locus_tag="KRM55_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1593004.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            15355..15741
                     /locus_tag="KRM55_000748"
     CDS             15355..15741
                     /locus_tag="KRM55_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1593005.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            15744..17543
                     /locus_tag="KRM55_000749"
     CDS             15744..17543
                     /locus_tag="KRM55_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBH1593006.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLVSWIIGILIMIAITIHCNIKIKNMKKSIQILRDDEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(17898..19772)
                     /locus_tag="KRM55_000750"
     CDS             complement(17898..19772)
                     /locus_tag="KRM55_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1593007.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(19777..21441)
                     /locus_tag="KRM55_000751"
     CDS             complement(19777..21441)
                     /locus_tag="KRM55_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBH1593008.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDESYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(21455..22276)
                     /locus_tag="KRM55_000752"
     CDS             complement(21455..22276)
                     /locus_tag="KRM55_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1593009.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(22375..23139)
                     /locus_tag="KRM55_000753"
     CDS             complement(22375..23139)
                     /locus_tag="KRM55_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1593010.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(23136..23885)
                     /locus_tag="KRM55_000754"
     CDS             complement(23136..23885)
                     /locus_tag="KRM55_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1593011.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(24389..24994)
                     /locus_tag="KRM55_000755"
     CDS             complement(24389..24994)
                     /locus_tag="KRM55_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1593012.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            25173..25811
                     /locus_tag="KRM55_000756"
     CDS             25173..25811
                     /locus_tag="KRM55_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1593013.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            25943..26605
                     /locus_tag="KRM55_000757"
     CDS             25943..26605
                     /locus_tag="KRM55_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593014.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            26605..27786
                     /locus_tag="KRM55_000758"
     CDS             26605..27786
                     /locus_tag="KRM55_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1593015.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(27967..30627)
                     /locus_tag="KRM55_000759"
     CDS             complement(27967..30627)
                     /locus_tag="KRM55_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593016.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(30624..31307)
                     /locus_tag="KRM55_000760"
     CDS             complement(30624..31307)
                     /locus_tag="KRM55_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593017.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(31651..32604)
                     /gene="blaCDD"
                     /locus_tag="KRM55_000761"
     CDS             complement(31651..32604)
                     /gene="blaCDD"
                     /locus_tag="KRM55_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH1593018.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(33145..35259)
                     /locus_tag="KRM55_000762"
     CDS             complement(33145..35259)
                     /locus_tag="KRM55_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HBH1593019.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLENVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMVEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTCELTQLIDM"
     gene            complement(35343..36179)
                     /locus_tag="KRM55_000763"
     CDS             complement(35343..36179)
                     /locus_tag="KRM55_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593020.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            complement(36774..37136)
                     /locus_tag="KRM55_000764"
     CDS             complement(36774..37136)
                     /locus_tag="KRM55_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1593021.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(37370..37834)
                     /locus_tag="KRM55_000765"
     CDS             complement(37370..37834)
                     /locus_tag="KRM55_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1593022.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLVKLDVEVGFPVATYIDGKNEILQKIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(38263..39684)
                     /gene="nhaC"
                     /locus_tag="KRM55_000766"
     CDS             complement(38263..39684)
                     /gene="nhaC"
                     /locus_tag="KRM55_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH1593023.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(39714..40778)
                     /locus_tag="KRM55_000767"
     CDS             complement(39714..40778)
                     /locus_tag="KRM55_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBH1593024.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(40763..42172)
                     /locus_tag="KRM55_000768"
     CDS             complement(40763..42172)
                     /locus_tag="KRM55_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBH1593025.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIKYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(42172..44376)
                     /locus_tag="KRM55_000769"
     CDS             complement(42172..44376)
                     /locus_tag="KRM55_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH1593026.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(44370..44744)
                     /locus_tag="KRM55_000770"
     CDS             complement(44370..44744)
                     /locus_tag="KRM55_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBH1593027.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(44822..46252)
                     /locus_tag="KRM55_000771"
     CDS             complement(44822..46252)
                     /locus_tag="KRM55_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBH1593028.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(46245..46553)
                     /locus_tag="KRM55_000772"
     CDS             complement(46245..46553)
                     /locus_tag="KRM55_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBH1593029.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(46674..47741)
                     /locus_tag="KRM55_000773"
     CDS             complement(46674..47741)
                     /locus_tag="KRM55_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBH1593030.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKINFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(47997..49370)
                     /locus_tag="KRM55_000774"
     CDS             complement(47997..49370)
                     /locus_tag="KRM55_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1593031.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILANSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIEKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            complement(49913..51871)
                     /locus_tag="KRM55_000775"
     CDS             complement(49913..51871)
                     /locus_tag="KRM55_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2075 domain-containing protein"
                     /protein_id="HBH1593032.1"
                     /translation="MKRAYYSSSVNEFIVKDIFTIFGEITCNDQFAADDLQKNTWKKE
                     IGILKRELSTFKDGHLLFEYTIPRIGSRIDNVLIYKGIVFLLEFKVDEDTYPRHAIEQ
                     VTDYALDLNCFHKESHDKLLVPILICTKAPQKDQRIRMMKENILETYCCNEFNIGKYI
                     KKICTTYNRSLFNSDTWINSLYMPTPTIIEAAQALYMGHNVEDISRNDASAKNLNQTT
                     KAINKIIDYSKTHNRKSICFITGVPGAGKTLAGLNIAIERQKVDENEHAVFLSGNGPL
                     VDVLQEALARDDVTRNGIRKSEAIRKAKEFIQIIHHFRDEAISVDTPPIERVTIFDEA
                     QRAWDEPNLTNFMKIKKGVLDFNMSEPEFLISILNRHIGWATIVCLIGGGQEINKGES
                     DGISGWFESLRNNYSDWDVYISNKIIDEEYSKGNSFDELTEGVNYRIIDDLHLSVSLR
                     SFRSENVSTFVKAVLDVDKVAAKELYNQFKKDYPICVTRDLELAKKWVRDKSKGSQRY
                     GMTASSGAKRLRKYGVWVQNKIDATNWFLNGKDDVRASYFLEETATEFDIQGLELDWT
                     IVCWDGNLRFKNNHFEYYNFNGTKWQNINKEDNILYLKNAYRVLLTRARQGFIIFVPI
                     GDESDITMQPNFYNGVYEYLKEIGIEEL"
     gene            complement(52064..53254)
                     /locus_tag="KRM55_000776"
     CDS             complement(52064..53254)
                     /locus_tag="KRM55_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HBH1593033.1"
                     /translation="MDKNKYKIETLMNHVGENLDGDYGAVNPPIYQSSIFARSTYEDI
                     EAYFEGSKDGYLYSRTKNPTNDILEAKLSALANAEASITFGSGMGAISSAILHFVKNG
                     DHIIASNNLYNPTMNFITKELKEKGNIENTIVEGDRIEDFENAIKQNTTLIYLECPST
                     AVFKMQDIKAIVALAKTHNIKTVIDNTWATPLYQRCIEMGIDLEVHSLSKYLNGHSDV
                     VGGCIIGSKKDIEEIRGSELALYGAKLAPFEAFLVIRGLRSLHARLSVHTKNAKEVVE
                     FLDNHSAVTKVYHPLSKYFNQKELAKKQLLNYTALLSFEIDAKDVNDVKKFVNKLDLF
                     KIGVSWGGHESLVFAPNIAILNEMTLEQAKALNVSPYTIRISLGLENSEDLINDLNDA
                     LSIL"
     gene            complement(53354..54820)
                     /locus_tag="KRM55_000777"
     CDS             complement(53354..54820)
                     /locus_tag="KRM55_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBH1593034.1"
                     /translation="MKREVTIQKQAISIVLFMAVLFCGLLLPMINNKPEYSLPIESIM
                     FISASIISLFIVVTTNKTWEEVFESGLDGVKGALPGLIILLVIGPLIAGFIMSGLMPM
                     LVYYGVKLINPRFVYATALILSALFSSFTGTSWGSAATIGVVMMGVGNAIGANNAIIA
                     GAIVGGAYFGDKMSPLSDTTNIAAIASKVNLYDHVASMLWTTGPATIIALVIYIACGF
                     IFPATNTNLNSPEITRLLADLSGMFNFNIILFIPLLIVLVGSAMKKPAIPVMTIAAFL
                     SLAFAVIFQGFSLADILIGLNSGFSLDMVTWHEYAKPIEGQAYILGFFQKGGFWELGK
                     LLPISTSILFVVGVLGSIDAMPATVNVIFGWVKSRTAIICSSLLTGIAMIAMTANGIA
                     CSFVTAGIFGDKYDENNIDRRVLSRTTEDTGTLLEVLFPWTPAAIFFTQTLGVNVGEY
                     ALWSIVNWGTPIIAVILAVTGIGTYKNSKDKKQSNKVS"
BASE COUNT        18515 a         9326 c         6514 g        20555 t
ORIGIN      
        1 taatttcatc cttgatttat ttaatatata aaaatatact aactttaatg attaagtttt
       61 gaaatataac taaaaatttg ataatttatt gagattttta tactaaaata tacatactat
      121 acaaacttaa tttagaaggg agcattctta tgaacaataa aatactcgtc gtagatgatg
      181 aggaaggtat aataacactc ttaaaagatt actttgaaat gaatggttat gaggtttaca
      241 ctgctcaaag tggaaaagac gcattaaaaa aaatatccaa aaatccagat atcattctac
      301 ttgatataaa catgcctgaa atagatggaa ttgaagtttg taatagaatt agagattatg
      361 tatcatgccc tattctattt cttacagcta gaattgaaaa cactgacaag ataaatggtt
      421 ttcgtgctgg tgctgatgat tatattgtaa aaccttttga tttagacgaa cttggagcta
      481 gagtatctgc ccatttaaga cgtgaacaaa ggaagtcaaa tcaaactaaa attaaatttt
      541 ataatgattt aacaatagat tacgaaaaaa ggttaatttg tatatataat aatcagattt
      601 cactttcaaa aaaggaattt gatatagtag agcttctctc tatgaatcct ggacaagtat
      661 ttgataaaga aaaaatatat gatagagtct ggggatacaa tagcaatgga aatagtgatg
      721 ttataatgga acacattaga aaaatacgaa tcaaactatc aaaacatact cttgaaaatt
      781 atatagaaac agtctgggga gttggttata aatggataaa ataaataata tgtcattaaa
      841 aaaagctttc tttgttctta ctttatcttc actaattata gcatcagtac ttactacttt
      901 cgcatacatt ttacttaata atctatataa ttctatacaa gataagtatt taaaaacacc
      961 tataaataca ggtattataa ccatagttca aaacaatgtg aaccaattta gtgattatga
     1021 taaaacatta cttaatataa tcaacatact ccagcttgta cttccactta tattttttat
     1081 aggactttta ttattagctg atataatttt ttacaaggta aaattaaaaa cacccataga
     1141 aatactcaat aaaggtgcaa tggaaatatc caacaacaat ttagactttt gcttagaata
     1201 taataataat gatgaattag gtaatctatg taatgctttt gaaaaaatga ggtctgaact
     1261 aaataaaaac aacataaaga tgtggactat gattaatgat agaaaacaac ttaatgctgc
     1321 tttttctcat gatttaagaa atcccctaac agttctaaaa ggttactcaa actatttaac
     1381 aaaatacata ccaacaggta agcttagtga tgagaagatt ttatcaacca cacaacttat
     1441 gtctgagcat attaacagaa ttgaatacta tgtagaaaat atgagtaatg ctcaacgatt
     1501 agaagattta gttgtttcaa aatctatgtc gaatataaac aagtttatag aaaacttaga
     1561 tgaaaatata tctatcattg ctaaacaaga aggaaaatct tttacactta aaaatcaaat
     1621 aaataatata aatctatttt ttgatgaaaa tatcattctt agagtcgtcg aaaatataat
     1681 atcgaatgct tttagatatg ctagaaataa tgtatccata cttatatatc ttgaacaaga
     1741 actccttacc tttgtaattg aagatgatgg tataggattt agtaaggaat ctctaaaatt
     1801 agctttaaga cctttctata gagataagac tttaaatgac agcaatgcac actttggtat
     1861 gggtctttat atctcaaaaa tattatgtga aaaacatggt ggctctattt ctattgaaaa
     1921 taattctact aacagtgcta aaattactgc taaattctca acaagaaatt aaaatgattt
     1981 tgtaagcttt cactgctatt atataaaatt tgttagttta gaatttataa aatgtatttc
     2041 aatttataac caatatatat actattttgt agaaattgta agagttgctt caattataat
     2101 attttggcaa aaggcatttg aaacaataat agaaatatat atttaaatat gtagaatagt
     2161 atgaaattag aattttggag gtgattatat taaaagtttt gctaataata ttacattctc
     2221 tcgtattgtg tttgcattgc taatgcttag ttttacattc tgttcactgc ctttctggat
     2281 atgttatttt tggtgtggaa ttagtgatat acttgatggt cttattgccc gaaagttgag
     2341 acaacaaagt ggaataggtg caaagttaga tagtattgct gatttcattt tttcggttac
     2401 aattttggtt actgtcggaa aaaatattgc tcttcccatg tatctatggt ggtgtattat
     2461 tgcaatagca ttgttacggt tgattagtta cagtattggt ttttttaagt atcgcacatt
     2521 ttcatcgctt catactttga tgaataaaat cactggaatt tctatctttg cgtttccatt
     2581 actctatatt tgctttggtc ttgatgttgc aggaattatg atatgtatcg tggcttttct
     2641 ttcttctttt gaagaaatag caattatgat aaaatcaaaa gaattaaatc gtgatataaa
     2701 aagtatattt atgtgaaaac ttagaatttg tgacaaaaat aatttatata ataatgagga
     2761 agtaaaacgt aaaaaattat ccacaagttt atgtgtaaaa tagttttaaa gcaatagagt
     2821 tgtattgtaa agcctttagt gcataaatta cattttaaat taaaaatgat actgaaactg
     2881 cttatcagca ctgcgaatta tccgcaaata gtgaagactt tttagattta agctaaaagt
     2941 tgggaaaaaa ttgagtttta aaacttacac tcttcttata tagaaaagga gagtgttttt
     3001 tatgattata aaagcaaaac aattatcaaa aatatatggt tctaataaca ataaagttat
     3061 cgcacttaat aatgtaaatt tagaaataaa ctcaggtgaa tttgtttctg taattggacc
     3121 ttctggaagt ggaaaaagca cacttttaca tattttaagt ggattagata atcctacctc
     3181 tggacaagtg ttacttgatg ataaagatat atataaacac actgaaaaag aactatctgc
     3241 acttagaaga aaatcctttg gattcgtctt tcaacaattt aatcttttac ctgttcttac
     3301 agcatctgaa aatatttcaa tgcctgtact tctagataaa aaacaacctg ataaaggcta
     3361 tttaaatgaa atttcatcat tacttggaat tgcagataga ctcaatcatc ttccccatga
     3421 actttcaggc ggtcagcaac aaagagttgc aattgctaga gcacttattg caaaaccaga
     3481 tataatattt gctgatgagc ctacaggaaa cttggacagt aaaagtggca gtgaagttat
     3541 gaatcttctt ataaaaactt caaaacagtt tggaaagact ttagtggtaa ttactcatga
     3601 tgatagaatt gcaaaacttg ctgatagaaa aatttcaatt attgatggtg ttcttatgga
     3661 ggtgaaatag aaatgaagaa ttacctttca ctttcaataa aagaattaaa aagccagaaa
     3721 cttatgacta cattcatcat tatagcaata gtactatcaa ctattatgac aactgtggtt
     3781 ggacagtcaa ttggtatcct acaaaattta agaattgaac aagcccgttc ttttaatggt
     3841 gatagacatg tatcctttca ccaactcact aaaaatcaag ttgatgacat aaagaaagat
     3901 gatagagttt atcaagctgg tacttcaata actattggca gtagtaaaat aaaggattct
     3961 ggtatctctg tacttgtaaa agagtatgat aaaacaggac tttctaacta cccaaaatta
     4021 atgaaattaa aatctggaca tttgcctaaa gataaaaacg aaatagcctt agatgaaaac
     4081 acactaaagc ttatgggtat aaaaccaaga ctaggagtga ctatacctat gaatttagat
     4141 atttcacttt taaatgatac cataccacca tataattaca cagctaactt taaattgagt
     4201 ggcattttag aggatgatta tacaggatat gtaagtggta tagtaaatgg tattgtaggt
     4261 aaaggtacat cagaaaatct attacctaag agatatactt tatcctcttt ggattttaaa
     4321 ataaaacagc aagaaaagtt tcaagaaata gtaaatcaat tagctaaaaa aataaatctt
     4381 tctcacaatt caattcaata taattggatt tacttaaatg ctcttaagat acagtttgaa
     4441 aaagatgaaa atagttctaa tagtgatggt atatctatga ttatattggt atctttattt
     4501 gttgccttat tggttttact ggcttctgga cttgtaatct ataatatttt aaaaatctct
     4561 gttacaaaga aaattaaaga gtatggatgt ttaagagcaa taggagctga accaaaccag
     4621 atatataaga tagttatttt acaaatctta attttatgta ctgttgccat acctattgga
     4681 gctgtaattg gaattatatc ttcgaaaggc ataactggaa tggtcactaa tatcttaaat
     4741 ccagatatac ttctagcaaa tgataataaa gaaattactg agcttataca taaaaataca
     4801 acagcatata tgttcccatt agtattaagc actaatgtat ctttgatttt ttcacttatt
     4861 tcagcattac catcagcaat atatgcttca catgtctctc ccaaaattgc tatggctggt
     4921 agtactacca aaatcaaaag aaaaattaaa agagaaaaaa caataaaaaa ctttgaaaga
     4981 catctagcat ggctaaactt aaaaagaaat aaaggaagaa ctataataac tatactatca
     5041 ttatttatga gtataacagt attcgttgca ctgagtgagt tctctaatgt attagatgta
     5101 tctaggtcag taagtaattt aaaagaagga gatttttcct taacaaatga aatatctggt
     5161 tttgataaat caacactaga taaaatagct aaaatgaaaa acgtcaatcg cacttccttt
     5221 ataaagtact ctgaatacaa acagggtgaa atagatacag atataaattt tgaaaatagt
     5281 ggtgagatgt taaaaatcat tggaattgat gagcaaactt taaaagactt aatgccttct
     5341 attacaaatt ctatactaga agactttaaa aatggttcta tctgttttat aaaaaatccg
     5401 attgctattt ctacaccagg tgtaaaaact agatatacaa atttaaaacc taaagatagt
     5461 atcacaatca acaaaaaaca actagatata tatagtacag tagataaaat gttcttttta
     5521 caaggcaatg gctggataaa tggtgttgat gttattgtat atgattctgt ttataacact
     5581 ttgacaaata aaaacaagtt caaccagata aatatttatg ctaaagataa atcaaaatta
     5641 gaacaaataa gattgtctat tgaacagatt tgtgaaaata atcctggctc tcattggata
     5701 tcatatattg aatcagataa acaacttaaa gagagtttta aacaaataga atttctagca
     5761 tgggcagtta tattatttgt gggattgatt ggtactttaa acatcattaa cacaactcat
     5821 acaaatataa atactaggac taatgagatt ggagttaaaa gagctattgg tatgagtaat
     5881 aggagcttat ataaaatgtt tttatgggaa ggtgtttatt atggaatttt tgctgctata
     5941 tttggttcaa ttgctgggta tgccagtgct attattataa acatggcaac tatagaaaag
     6001 cttgatttca ctaatatacc aattacttca attttacaag ctactattat ttctgtactt
     6061 acatgtatta tagctactct tattccgtta agaaaagtta aaaagatgaa tataattgac
     6121 tgtatagata tcaatttata actattttac agataataat ataaattaaa ttatcaatga
     6181 ctgtctctat tttctttcaa atctaactaa taaatctttt taactataat ataagcttta
     6241 aaaaaggcct gtctcaaaat agagataagc cttttttcat tgtcgaaata atgaaaatat
     6301 atttaacttc acaaaaaaag agtgcctcac gaattaaaaa tttcgctttg agacactctc
     6361 ctttaattta aaatatatag ttaaatgcta tgccaaaatt tcacacatgc tccacctgat
     6421 tttgaatttt ctattttaac agaacctcca agctgttcca ctaattgttt gacaatgtaa
     6481 agcccaagac cagaatgtcc accttttgtc tgcctagctt catctcctcg ataaaattta
     6541 tcaagagcct tttttaaatc tttagagcta aaccctctac cagaatcaca aatctcataa
     6601 gaaatacaat ttttttcatc ctttacagta atactaatat taccacctga tggagtgtat
     6661 tgcagactgt tggatatgat attatcaaaa attcgtgtca acctatccac gtcgatttga
     6721 attggggatt gtatattccc ctgcattttc aatataagtt caacttcctt ttgatgagcc
     6781 tgtaattcat agtcttgcac cttttgcctc aaaaattcag gtaaatttat aggaacaaga
     6841 tttaattgta tatttgactt ttctaagtca gacgtatatt gcatcttttg gacaagagca
     6901 gcactttttt ctgtattttc tcttatcact gtaagatacc tatgaagttt ttcattgtca
     6961 tctgtattat taccaataag tgcatctgta tatcccaaaa taatagaaag aggagatttt
     7021 aaatcatgtg ctagagcttc caccatttca acacgttcct gctccatctt ccactgtgca
     7081 gataaagagc cttttaattc gtctttcatt tcagaaaatg cactacaaag tttaccgagt
     7141 tcattatctg aataatagtc gatttcaaaa tcaaggtcct tttcttttat cttcttggac
     7201 gcatcaatca atagatgtaa tggttgattg atattcttta caaagcgctt agaaagccat
     7261 ctagtaaaac ccacgatata tagaaatgga gaaaacaaag ccattataat aactgcaaat
     7321 acaaatctcc ctctaatatt tgcaaaggtg attttcactt ggtagaatag aataacagca
     7381 ccctcaatct ttccattatc ccctttgatt ggaacagtat ggatataacc acctttacga
     7441 acagttttat tgataaaatt attaaataat tcttcttttg ttttaaatag ttttttgggg
     7501 ttagtaccat ataaaatatt gccattatta tccacaactt gatatagcat atcatcccca
     7561 cgaatcgttc tttttaaacc ttcttcattc gattgtgata acaaagctat gtttttttca
     7621 ttgatgtatt tttcaattct aggaacttgt cgctcataat agtttggtgg atagatatcc
     7681 ttatttaagg aatgaatata caaatagaga gcaaatacat aagtaatcac tgtggcaact
     7741 atactggcta ttataataaa aataaaagta tgtctaaatt gggtaataag ggattgattt
     7801 ttcatttaat aacctctctc tctttacatt ttattccact tatacccaat accccaaact
     7861 gtggaaatat attctttttc tggtgtcaca gcagaaaact tagctcgtat tttttttact
     7921 cgttcaacaa cagttgagga atcaccttca gaatcacacc cccatacttt ttcatagatt
     7981 tgttctcttg agaaaacttg tcctgcatgg agtgctagta attcaacaat atcatactct
     8041 atttttgtta aatcaatatt cttaccatca attttaattg cacgttcctt catatataag
     8101 cataacttcc caaaatacaa agtagatctc ttgttctctt cattgatata ctgtgaacgc
     8161 ttttccctac gcagattagc ttcaatcctt gccataagtt cacgcagtcc aaatggcttt
     8221 gttacataat catcccctcc aaaggtcaac cctttgattt tgtcggtttc tgattgcttt
     8281 gcacttaaaa atataattgg gcataaaaca tcatctctaa ttgcctgaca tacctcaaat
     8341 ccattcattt taggcatcat aatatccagt ataataaggt caggctcctg ttttgataac
     8401 tctatacctg cctgaccatc ataagctatc aacacttcat gtccttttgc cttcaattca
     8461 tcctcaagta gcattactag gtccatttca tcatcaataa tcaatatttt actcaatata
     8521 acaccacctt tctcttatgg gaaggtcagt attaaaacaa tattcgtcta ctcataactt
     8581 ttccttccct cccacatttt aaaccaaata acgcctccta tcaagaatat aatcaaacct
     8641 attgctacta ctataagctc tatactagct gtttgcatca ctttagagta aaatgcctca
     8701 gttgaaatag ttccagcttc tttaataaaa taaattcctg gaagcatacc tagttttact
     8761 ggccatgtcc atggaacaaa tgcccatact ttttcaccaa cgctagttaa tccaagtatt
     8821 gctgccatca aaattccacc aatactaata ccaatagatg cacccatacc ccatgcaaaa
     8881 ctcacccaaa gatgaatagc taatagtgga agtgtcccaa tcaccacaag tcctgctgct
     8941 gacaggaata accatattgt tgctccagat ggcactgcaa tactcattcc tatgcaaagt
     9001 atcaacgtag caataaatgt gcatatagtt aggcaaaaca gaagaaaaag aaattttccc
     9061 agatataatc tgacacgaga aatacctaca cataaaaaac cattaaaatt tccagcaagc
     9121 tcttcctcct gcactataaa tcctgctaaa atacctactc caataggaat gatgaataca
     9181 gtccatactg taaaaaatcc ttcaaaagca aattcttgtg tacttccaga tttagttgtg
     9241 agataaaaaa ccacacataa tgaaaaaata ataggcatac aaagagtaag ccactggaca
     9301 gctgtcctct ttgctcgaag ccattctgat gataatagtt ttatcatttg tcatccctcc
     9361 tattgaacca agctgcagta agtgctgtta atactataaa cacaaccaaa gaaacaacaa
     9421 tcccaatagg aatcactgaa gtattcaaaa gtgggtctcc agcttctaat atagtaccgt
     9481 taggatgtat gttgatgatt gggcatacca ttctaactgc ccaactccaa ggtactgcaa
     9541 tccaaaatgg ttttgtcgca gcaagaacac caaatatcat acctaaagct ccaactccca
     9601 tacttaggaa catacctttc catgtagcta gccatagctg aagtggaagt atagcaagag
     9661 aaacaaccca gcatacaata cttgccccta taatctgtcc aaaaggaact ggaccagctt
     9721 tcaatattaa accagttata attgttacga ctattaaaac tagcgttgaa ataaaactgt
     9781 agactgccat agctataact ttattaatcc aaagtgtcat aggagacaca ttgtgtgtac
     9841 gtaaagcacg ataatttcca gctttttttt cctggaaagc taccaaagta gcgaacaatg
     9901 caaatccaat aggcagaaat aaaaatgacc accagttaaa aattaatgct aaaagatttt
     9961 gccacgccca agaagttgtt tgagataatg gattttgcat gagtgttgat tgcattataa
    10021 atgcatatgc tgcaaaagac actgggaaaa aaacaataag tttacccata aatgttcttt
    10081 tatactttaa aagttctgat tgtaaagcat tcatctgttt tgtcctcctt taagaataac
    10141 atctgtaaaa aattcttcta gattttcatt agggtcaggc attccttgaa ataatagtcg
    10201 tcctccattt ataattccta tattatctac aacttgagca acctctgata gaatatggct
    10261 agaaagaatt acagttatac cttttttggg aaaagaagca atcaattcac gcaattcttg
    10321 aatgccaaag gggtcaagac cattggttgg ttcatctagt attaacaact ctgggtcact
    10381 caaaagtgca atagctattc ctaacctttg tttcataccc atagaaaatt gtgaagctct
    10441 ctttttacct gtatttttca aatttactat ttccaacact tcataaattt tatctttagg
    10501 tattcccaat atttttgtat gtactaacaa attttcctct gctgtaaggt ttccatacaa
    10561 tgcaggggat tctattaaag aacctatttt tgcaagagat tctcgtttcc aaggctttct
    10621 atcaaaaata atacgaccat ttgttgggcg aagaagacca acaagcattt taagtgttgt
    10681 ggactttcct gctccatttg gtcctaaaag tccatatata ctatttcgtt caatttgtag
    10741 agaaacattg ttaactgcca tttgttctcc atatcttttt gataagtttt ttgtttcaag
    10801 aattaaatct ttcatattaa tttctccctt cttgtaatac cttaaatctg ttactaagag
    10861 aatactaaca tgaaaaaata acaattctat aacacctact aattttaata aaatttaaaa
    10921 taaaaaatag agttaccaat tttattttgg caactctatt taagtttatg ttttacagtt
    10981 atattagatt taaacttagt ttcattatca cactaacttc aaatttactc tataatcttt
    11041 aaatcaaaca ctaatctatt aatttatatt tctttagaca tctaatatag tttgctacta
    11101 aataataatt atttatatca tatttatcta atcctttaaa agaagttatt tcatcattaa
    11161 gctcatcact accttctaca aaaacacaac ctgtttcaaa gtccatacct acaataatct
    11221 tacagccact ataaatttcc tcttgagtat cgtacaattt ttttgcattt ccttcatttg
    11281 gaattgtaaa tacaataggt tttaattctt tatcactgga aatcttttgt gaaaaaggct
    11341 tgtttaactt aatattattg ataactacat gtttaaattc ctctgaagtt tcttctacta
    11401 ttacatattt tcgctttaaa aactctatta tttctaaaac agacttagaa tttactttta
    11461 aaatactttt atatttttca tataaagatt tccactgttc aattttttcc tgtggtactt
    11521 cttggatatg tgtacttatt ttttcttgag atattttttt caattaaact ctcctttcaa
    11581 tacttaaata tccttataaa tctcacatga ctaaagttac aaggttccta cttaatagaa
    11641 ttttgcatac ttaaatatgt cttattaatt ctctacagga tatctccgta gttcctacga
    11701 ttcttacata agttacttat tttaaattgt tattagttat attctaaaaa ttatttattt
    11761 tatcactaat ataatactct taaaaacttt acaaatcaat ttaaatttgc taccttttat
    11821 ttataacaac ttatagtaca tttctcctat gcttttcaat atattacttt taaaaggagg
    11881 ttttcattat gattttaaat agagctgagc ttttccgagg atattcttta aatagattta
    11941 acgagatatg caatatatta tcagtaaata aaattaaata taagtataaa gtgaaaaata
    12001 atgcttactc taaaaaacct ttttttaatg aaataacact tggcaattta ggtcaaaagg
    12061 aagatttctc ttatgagtac ttaatttatg ttcataaaga cgattatgaa caggcagagt
    12121 ctctaataaa ttctaagttg cgatagatta tttataaaac atgacattct gttgtcatgt
    12181 tttatatgtt attatacttt caaatatgct actatatttt caaaattgtg tgctttaaaa
    12241 ctagcttttt atagtaattt aaagcttaaa actaaggaga ctcgttatat gaaaataaat
    12301 ataaaatcaa agttaagtga atttattaaa cagaacaatc tttttgatga cagcagaata
    12361 atatcctacc ttcctaatat aacaatagaa acagacaaaa taaaaactat aatgattaat
    12421 gaggttgtcc caactaacac caatgacgat ttttatagtg tagataaaga tgctgattat
    12481 ttaaaaacta ctattccttt atttgacagt gcaggaatag aagtatctag cataaatgat
    12541 atcctagata tgggtatcta tataactaat gcagtaaaac ttcctaaatc agaatataca
    12601 ataactcgtg atacaattaa attacatatg cctattttag aagaagaaat taaattattt
    12661 aaaaacctag aggtagtaat gttaatggga gatgttgcaa aaaaatcttt taatatgatt
    12721 actaaaaagc atataaaaaa gaatgtcatc ccttccattt caacatataa acttcgtaat
    12781 aatgaacttt attatgataa tttaagagta tttccatcat atattatgac tggtggaaac
    12841 atactgattg aaaaatcaaa atttgaaatg gcatcagaag atataaaaaa aatgttcgag
    12901 attataaacg gttgatatta caaaataata aaaactaata taaaataaaa gtgcattaaa
    12961 aacttctatt tatgaggcac ttttatttta tattagtgta actatatact attaacataa
    13021 tttattattt atattgttct ttttaatctc tattccattt agtctaggta acattactct
    13081 ttacaagatt actttatatt tcttttatat ctctaacgtt tttatttaat aaaacaatta
    13141 ttaatacaag tcaaatatat ctatttatct aaaaatatat cttttacagt aatatctgga
    13201 tggtgatact tcttcctatt cgttaaaaaa gattttttta cattaatagc ctcttttgga
    13261 caccagtgaa aacaagctag gcatctttca cactcattac cccactttgg ctttttatca
    13321 actatactta tattctctac aggacaaacc cttttacatg tcccacatcc attacattta
    13381 ttttctgcaa aaaatttagt agttgcaatt tgcatattct tacctactaa acgaagtaca
    13441 acactatcta tatgtgactt taaattgttt tttccttcta tatttccaat ctccaagtta
    13501 ttgatacatt ttgcaatctc agctacccta ttagtctgat ttttcaatct ttcttcttca
    13561 acatctggag gtgttatcaa agcatttcca ggcatattga ttaaaaaacc agcagataat
    13621 tttttccccc tttttttaag taacttatct atagtaaata aactatgtcc agctacccca
    13681 ttacaagtgg caatggcata tatatgagta ttaatattaa aatttaattt ctctacaaaa
    13741 gactttacta tatcaggaac atcagcaaaa taaacaggaa aaacaattac caatatatct
    13801 tcatttatgt ctatattatt ttcttttcta tgtatagcta agggtataac ttctttactt
    13861 ccatttaacg tttcttttaa aatatttgaa actactagcg aatttcctgt tccagaaaaa
    13921 taataaatct tactattcat tcttatccct ctttctatat ttctacatca tcaatagtta
    13981 aaaagtctct taaaatagga tttatattta ctttccaatt ctatccaaaa tatcagtaaa
    14041 caaaggcaat tcttcatcag agatagattt aaatgtctct gttgcatata tacttgcaat
    14101 ttcatttaat ggttcttcta attctctacc taaatctgtt aggaatattt gaaacttacg
    14161 tctatcttta acatctactt tacggacaat taatccctta tttttcataa catctaagat
    14221 tcttgtcgta ttagatttat ccttacatga tttttcacat aaatctatct gagaaattcc
    14281 atcttgctcc catagaaacc ttaataacgc ataatggtca gttgttatat catatccatt
    14341 ttgtttaaac atctttttta aatcatcttt tacttttaac gaagtactta ctaacttagt
    14401 tgtagcttca tatagtttct caaaatcttt cattttacct ccatttaaat aatcccttgc
    14461 tcctcccatc tatcaattat tcccttatat tgctcaatat ctttaaaagc cattggcttt
    14521 aaaacagcat ttatagcaat aaaattatag atttgagaaa gcacaggtgg atttttcttt
    14581 tcctctatgc aataaataaa ttttttagat accttttgta tctttgattc tactttttca
    14641 gttataggat tttgattaaa tccagttttt atagataaac taccacaaac ataacctccc
    14701 gaatctaaga ccatggattt tataaaagaa attgcttttg aaccacgtgc attttcatat
    14761 gtagtaactg ctatacatgg cttacgatac aataatcttt caagcatcat atgtgctcta
    14821 tctgtaaaca ccttgaaaag tccagttaca ctacttccat aagttgggct accaaatata
    14881 acaccatcac tcttagtaat tatatcatga atatactcta ctttatcatt ttgattgata
    14941 cacttgccca ttttataaca atttaaacaa ccaatacaat atgatggatt gacctcactt
    15001 aaatcaaaat aattaatttt tacatctggt attaatcttt ctatatcttt atacaagtaa
    15061 gtcaaaactt ttgatgtagc tccatttttt ctagggcttc catttataac tgtaattatc
    15121 atttctatat ctccttttta gttgttatat caacaataag tatatcaact atatttttag
    15181 ctgtcaatat aaaccattta tttaaagcta tacttacaca gcttaaataa aagttttatt
    15241 taactacatg tgcttattta atcaactata aatgaattat ttttaataat tgacaaacta
    15301 aattaatgat aatatacttt atgtattaca aatgtaagta gaaggaggta tagtatgaaa
    15361 aagttaccac atatttcaga agcagaatat caagttatga aaattatttg gaaatatgct
    15421 cctatcagca ctactgaagt aattgaaaag ttggtagaaa caagtacatg gagtcctaaa
    15481 acaattcaaa caatgttatt gagattagtt aaaaaaggag ctttaacata tgaaaaaaat
    15541 agcagagtat tcgtttatac tccacttgtt aaagaagaag aatacgtagc tacagaaagt
    15601 agttcttttt taaatcgttt ttataatggt actcttaatt ctatggtact aaacttttta
    15661 gaaaatgata aactatctga agatgatatt gaggaactga gagaaatctt aaataaaagg
    15721 acgactaagg gggataaata aatatgtatg ccccattctt tatacgattt ttactcagta
    15781 cattaacctt atcaatatta attgttgtaa ttttacttgc caaaaaagta tttaaaaaac
    15841 atatttctgc aaagtaccaa tacaatattg gatttatatt gcttataatg ttaataattc
    15901 catttgtccc tcttaaatat attaatcttg gaaatgtatt taactattta tatactttta
    15961 atcaacttgg aagcagtact aataggactt ctatgataaa aaatagtcca aattctataa
    16021 ttaataactc aaatgcatta aacgattttt cagtatccct aaaccaagtt aattttgata
    16081 gtttaaatat tttattacta gtatcatgga taattggaat tttaatcatg atagctatta
    16141 ctattcattg caacattaaa ataaaaaata tgaaaaaatc aatacaaatt ttaagagatg
    16201 atgagatagt atttatattt gaaaagtgta aaaaagatat tggtataaat aaggatttta
    16261 tactatgcaa atcacctatt ataaatacac ctattacatt tggatacttt aaaccacaca
    16321 ttatattacc agataagtct atatctaaat tatctttaaa agatataaaa tatatcttac
    16381 ttcatgaatt acaacatttt aaaaataaag atatactgat aaattatata atgtgctttc
    16441 ttcaaatatt atattggttt aatcctcttg tatggtatgc atttaaagaa atgcgtatag
    16501 accgtgaaat tgcatgtgat atttcagttt taaaaaagct tgataaagat agtcatatag
    16561 aatatggaca aactctaata aactttgtgg ataatatttc aagaccatca aatcttacac
    16621 ttacatcaga tattggtggg tcaaaaaaac aaataaaaaa gcgactattg aagataatgg
    16681 attttcataa tgaatcaaat acgttaaaat tcaaaagcat tttaattttt acattgatag
    16741 ctttaattgt atttggaaat attcccaaac tatctattat ggcagatatc aacgaaaaat
    16801 atagacctac aaatgaacaa actgtgtacg aggacttaag tcagtatttt aaaggttttg
    16861 atggaagttt tgttatgtat gatttaaaat ccaagcaata tcatatttac aataaagaaa
    16921 aaagtaaaac aagaatttct ccaaattcta cttataagat ttatagtgcc ttattgggat
    16981 tggaaaatgg gataataaca agaaataatt cacatatccc ttgggatgga aagcatcatt
    17041 ctaatagttc ttggaatgaa gaccaagact tattttctgc tatggaaaac tccgtaaact
    17101 ggtactttca gactctagat aaaaaaacag gtctaaaaaa catacaaact tatcttaggc
    17161 aaattggata tggcaattat gatgtttcag gtggtatctc aaacttttgg ctagaatctt
    17221 cattaaaaat atcacctatt gaacaggtag aattacttga aagtttttat acaaataagt
    17281 ttaaatttga agataaaaat atagaaacag taaaagattc attgttaata tcaaaaaagg
    17341 atggggtatc actttttggt aaaacaggca ctgccaatat aaatggaaaa gatgtaaatg
    17401 gttggtttat aggttatgtg gaaaaaaatg aaaatactta tttctttgct acaaatattc
    17461 aaagcaaaga ttattctaat ggtagttcag catctaagat aacattatcc atattaaatg
    17521 acaaaaaaat ctataatcct taatatattt actgtacatt ctaaaaaatt cacataattt
    17581 tcatattaat tatcaattaa attcatatac aaggcttatt atataaacat agaagatagt
    17641 aaaactagct taaaaacata atataatacc ctatacaaat agtggcaact ctccctcaca
    17701 tcctcaattg ttgccactat ttaatttttt gtatgaagtt aaatatattt tcatcatttc
    17761 aacaatttgg gtgcaataca atctctattt tgaaacaacc tctttaattg ttttagagtt
    17821 tatgaattat ttctgatact ttaaaaagat tgaattactc ttgataatct tcttttgtag
    17881 tcattacata tcacctacta ctcaacacat attctttgac ctatttttac atccttgttt
    17941 atatccaaaa tatttacctt cttaccatct ggaaacaata ccattgtcaa agtagacttt
    18001 cctaattcgt gtattctctt taaatcaaca ttaacaagaa catctccctg tttaaccata
    18061 tctccttgtt taacagcaac atcaaagcca tctccattta atgcaactgt atcaattcca
    18121 acatgaatta atacttctcc attagttcct ttaatcccaa atgcatgtcc acttgaaaat
    18181 actgtttcta atttacctga aataggagaa acaatttttc catctataat atcaatagca
    18241 aaaccatcac ctaacatttt tttagaaaat gtttcatctg gtacattttc taatgcaaca
    18301 attttcccct tagctggaga cacaaagttt tcattatttt cattaaacac taattcttcg
    18361 tcttcatctt catttatagc ttctttaggc actccaaata aacatgttac aataaagcag
    18421 aatgcaacca caaatattga tactaataag tatgtgatta aattatatcc atcatagata
    18481 tacattaaat aagaaggtaa aactgctaat ccatatgaat tagattgaat atgtaaaatt
    18541 gataatattg ctgctcctaa acctgaagat gcacacataa taatcaaagg ctttaaatta
    18601 tatcgaagct gaatcccaaa taaaacaggc tcacttatac caaaaagttg agatagcatt
    18661 gctccaaccg cagtttgttt aacttgatta tttttagatt ttttcataaa tgctagacat
    18721 gttccaatat tcgcaaatcc atacattgca caaagagtaa taagggcatt aaatcctgta
    18781 tttgctaata gtgatgtttc aatcattaca taagtatgat gtaagccagt aataacagct
    18841 aatggatatg taaatccaat aataaatcct ccaattccta aaggcaaatc aatcaataag
    18901 ctgatgatat caaccatttt taattctatt gtatgcatta tagggcctac acctaacaaa
    18961 ataactaaca ttgttattag cataacaaaa aatggtgtga aaataaggtc taatacatta
    19021 ggcatatgtt tacggaacca tttttcaaga ttagctccaa taaatgctgt aacaatagct
    19081 gttaaaacac ttccttgaca acctacaata ggaataaatc caaatgccat aattgcttca
    19141 atttcatttg atgggtcagc aacagaatat gcattaggaa gtattgggga aactaacata
    19201 agtccaataa caagtccaat aacaggtgtt cctccaaata ctttaaatgc tgaccataca
    19261 ataattgctg gtaaaaaagc aaatgctgtt tctgtaagaa ccgaaacaag tgtctgaata
    19321 tacaatggaa tatttgcaga agacattcca aataatccaa gtacattatc attaaacaaa
    19381 caacccttta atcccaagaa taatcctgtt gctgcaataa ctggaataat aggaacaaat
    19441 atatctgcta gagttctcat aactttctta aatccagttt cattattttt aactaattca
    19501 tcttgttctt tttttgataa agtttttaat cccatttttt caacttctgc ataaacttta
    19561 ttaactattc ctgttcctaa aataatttga tactgtccag aagtaaagaa aaccccttta
    19621 acctcatcaa ctttttcaac tttcttatca ttaataattt ctctatcttt aaccatcact
    19681 cttaatcttg tggcacaatg tgtaatagaa ataatattat cttcaccaat aattttaata
    19741 agctcatttg ctattttatt atatttattc atttttctac ctcactttca ataatactgc
    19801 atgaaatggt ttcaaacgca ctgttttatt taatagattt atatcatcta aattttggaa
    19861 tacaatatca tatttttctt ctactcttat ttctacaggt ttatcagaaa aattataata
    19921 acaatcaata actaccaaat ctaattgcct tctatacgca ataatatcat cactttctat
    19981 atcaataggt tctattgaac cataaatcaa acaatcagaa tactcactat cttgtctcaa
    20041 ctttatcatc tttttataaa attctaaaat actctctgaa ttgttaatct gactctgtgc
    20101 attaatatct ttataatttt caataacctt taaccatggt gttgtatctg aaaaacctgc
    20161 attttcttta tctgcccatg gaaatggcgt tcttgcatta tctcggcttc ttaaattcac
    20221 aaattctaac gcttcttctt ctgagtaact ttcatctatt gaacgatagt attggtcaat
    20281 gctagataaa tcattaaaat catttatggt atctctttta aaatttgtca ttcctaattc
    20341 ctgtccctga taaataaatg gggttcctct taaaaagaaa tacattgctc ccaacatttt
    20401 tactgcatca tcattccttt cgtattgcaa aagatacttt gttgtagctc ttggttggtc
    20461 atgattttca ataaaattag ctgcccatcc atgttcctga acatacattt gactatctaa
    20521 aatgcatttt cttaaatctg gaattgtcca tgaaattctt ttaaaccact cactaccaga
    20581 agcaacatct aagtcagcat gtttaaagtc aaagaccatt gaaaagaaac catcttctcc
    20641 aataaaatca cctagttggt catagctaat acctgctgct tcagcaacag tcatacaatc
    20701 atatttttta aacgtatttt cttttaattc ataaagcatt ttttctattc caggctgatt
    20761 tctaactgtt tttgtacatt taacaagacc atcaacacca tcactttcta aactttgaaa
    20821 acttaaattc tttttgataa atgtaatagc atcaactcta aatcctgcca ctcccatttg
    20881 agaccaggta ttaatcattt ggtaaagttc acttcttaat attggatttt cccaattaag
    20941 gtcaggttgt tttttaccaa aagaatgaaa ataatattcg tctctattct ctaccttttc
    21001 ccaaacactt ccaccaaaaa cagacctcca gttatttggt aaatcgtttc cttttttaaa
    21061 aatataataa tcatgataag gactttctgg attttttaat gcttcttgaa accaaggatg
    21121 ttcatcactt gtatgattaa gaactaaatc taatataatt ttgattcctc tatctttact
    21181 ttctttaatt aactctttta aatcttccat acttccaaat tcacttgcaa tatccaaata
    21241 atcactaata tcatacccat tatcgtccat aggtgattta aaaattggac ataaccacaa
    21301 tgatgtaata cctaaatctt ttaaataatc taaacgagaa ataattccct gtaaatctcc
    21361 aattccatca ttattactat cttgaaagct tcttggataa atttgataaa cgatttcttt
    21421 ttgccaccat ttcttttcca taaattactc ctttttatat gatatttctt ctttttaatt
    21481 ctttataaat tccattatcg aatatgtcct cacatataga tgtcgctata tctttaagtt
    21541 gttgatgact atttttcatt gcaattgtaa cgtctgatgc ttgaaacatg acaatgtcat
    21601 tttgaccatc accaaaacat atggtttctt tttgagttac tcctaatctt tcttgtaatc
    21661 tcttaattgc tttgccctta tgaaaatctt tttgaataat ttcataatac tgactagaaa
    21721 tatctctctg tgctaattcc attttatctt gtagtatatc tttcacttcg tcaaatacct
    21781 tttcatttga ccataaacaa attttatgta tatcttgtga cttatactct tcaatgttat
    21841 tttcatatgt tattttttct tggatatgtt gtttatttat acaagaatta gttcctttta
    21901 actgattcat tgtttcaaat atttctttgg ctttttgatt catgaaaact ttttcctgac
    21961 tctcaatcga aaaagcaact tctctctttt ttaataaaca aacaacttcc tttatcaatc
    22021 tttgattaaa agattgatta taaagtaatt caccatgata ttgaatgtaa ttacctcctc
    22081 ctgcaatata tccatcaact cctaatgata aaacatcatc ttgtattgta cccatacttc
    22141 ttccagtaca aataacaaca ctgcaatgat tcttttgaca taaacgtata gcatgctttg
    22201 cagattctgg gattccatat acctcatctc taagcgtacc atctatatca agtattaata
    22261 atttgtacaa tttcatcttc ctttcttact atcaaaatca taatagcatt caaaaaaaaa
    22321 gatatcaata ttttgatatc ttttaaaaaa tatgttcatt tttagcacaa attttcattt
    22381 tcggggaata tgttcacttt ctaaatacat cttgtattta atataaagca gttcaattaa
    22441 aataaaataa ggtgttgtta catcgtagtc cagttgttta tctacagaaa tagatataga
    22501 ttgaatatac aggttttcat cacataatct tgctaaagga ttacttatca tttttgtaat
    22561 agaaaccata taaattcctt tcattctcat ttctttagca aaatcaataa ttgtagatgc
    22621 atctccattc aatgaaataa agaaaatcat atcatctgtt tttataaaat gattaagtgc
    22681 ctgaatcata tcataaccat aaacatcata tataattttc cctgttggta agaaaatcct
    22741 tttcatctct ttagcaactc tttcctgaga ataaccttct ccaaagacga ttatacgatt
    22801 tgcctttttc attctttcaa acataatcga acaatccttc ttctctatat catctatcac
    22861 cttattataa caatccatta attggtgttt actttgattt ttatattcta cttctgtttc
    22921 atttaagcgt ataataactc ttaattcact atatccaggt aattgtagtt tttgagcaaa
    22981 acgagaaagt gcacttgtag atatatggta tttgtctgca aattcatcta tagaaagttt
    23041 aatacaatct tctttatgat taagaataca ctcacagata tacttatcat ttgctgtaaa
    23101 tgaattataa tatttattga aaagtccttc aattttcatt cttttctcct tctatactct
    23161 atgtaattca tatgaagcaa atctaataga gcataaaatg ctcctacgac ttcataagat
    23221 atagcttgta atgtatcaag tttttgcgtt tcaacataca gattatactc acaaagtgtt
    23281 gcaattgtat tattatcaag cctagttaaa gaaatcgtat gtatatgatt gttgataaat
    23341 tttgcaattt caattcctgc ttttgtttct ccagacaaag aaatgataat aaataaatca
    23401 tttttttgaa atgattctct cataaattca atttcaccta tatcaaataa gtcaataaca
    23461 catttaccta ctgaaagaaa tattctcttt atttcttgag ctaaactttt ctgttcatta
    23521 cctgtcccat aaatataaat tgtttctgca tcatatatta ttttacaaat atcttgaaat
    23581 gatatttttt gtaattcatt cattaatagt cgataattct cgcaaacatc atgaaaatta
    23641 ttatcattat taacaaattc tagttgatta tttttaagta aatactttaa atcagagaat
    23701 gaatctaatc caatttttct acaaagcctt aataaagtag ctctagaaac attacattca
    23761 tttgcaattt tttcacacga aaaattacgg tattctcttt gacaaatcaa tatttgttta
    23821 ataataattt tatcattttc atttaaatta tcataatttt ggttaactaa cgattctaat
    23881 ctcatttttt ccactcccta aatattattt taatatacat tagttgcttt ttctagggaa
    23941 gagttttaaa taataaggat aaaataatca tttgatttta tttttattaa aataaaaata
    24001 acctgctaaa agcaggcacc aaaaagtact tatcctttcg aacatgtact ttagatattg
    24061 ctttcttcgg aagcttcatc tcttcatact ctaaaatata gttttttcta actcaaaagt
    24121 attttccatg gtagaaatta ctttaattca tctgccattt actttttatc ttatttaata
    24181 attactatta cttgaatatt tacttcttta agtaaatttc atagttaaca aagctaaaac
    24241 tattattata gatgttaaaa tacaaaattg taagtattgt tataaatatg cttacagcta
    24301 caaatataca tgatatatta aaaagaagct gtaaattatt atcatacata caagcaacta
    24361 tgcctctatt aatccatgtt aatttttatt atttaataca aggagttcca tgagacatac
    24421 atatccattc atattttaaa ttatccaatt ctcttataga tttcaccatc tttttataat
    24481 cccaattcca tggattagga taaggaacta tatttccatt cttatttttg actaaatcac
    24541 ctgcaaataa tacagcttca aaaatcatgc agacatgccc tggagtatga ccaggagtat
    24601 ggataatttt tatattccca atctgcatat tctctccata aggttcaaca tccttaatga
    24661 gccttctgga aattgccttt ccaataaact tcttaaaccc aggtctatcc ttctctccta
    24721 taataaaagg tatatcctct acatgagccc atacttttgc tcctgttttt tctttcaata
    24781 atttaatatt agatatatgg tcaacatcat gatgagttaa taaaatatgc ttaatatctg
    24841 taagtttaat gccaagtgtt tttaattctt taattatatt tttccccata aaaggaagac
    24901 ctgtgtctat aagaataatt tctttatcaa acacaataaa acaatttgag ccacgagtac
    24961 tatctaacat taatacattt tcttttatct tcataaataa attcccctta tttggtattt
    25021 tacctatata attaattaat aaagttataa atagttataa tacttgatat taattttatt
    25081 ttttattaaa gtatactata ggtatacaag tattatattt acataagtat accatcagta
    25141 tactttttta tcaatagaaa ggaataattt atatgtcaga attatcaaaa agagataaag
    25201 aaaaaataca aagagaaaat gagattattg ataaggcaga aaaattattt tgtcttaatg
    25261 gatttgataa tacaactatg aatgaattag caaaagaagt tgaatatact aaacgcacca
    25321 tatacaagta cttttcatgt aaagaagatt tattctttgc tgttgtctta agaggatata
    25381 aaagactttg ggataatgtt aaaatagaaa gtgcaaaagg caaaacaggg tttgaaaaaa
    25441 taaaactttc atactttgct tttcataaat tttactctgt agaaccttct ctattatgcc
    25501 ttatgggaat gattggtatt gtaaactctg aaaaatcgga tactgatatg ctgtttaaag
    25561 aaaagttttt ttcttttaat aaatttatgt ttgatgaaat acaaggaatg tttgaaattg
    25621 gaaaaaatga tagaagtatt aggcatgata ttgaaatacc tactcttatg tattcatcaa
    25681 tatttacact tacaggattt tttaatttac tatctgtaac aggaaaatca tacctgaaca
    25741 actttaatat agatgaggaa aaatttattg aaacaactct tgctctttta atagattcaa
    25801 ttaaagcata aacctaagtt tataaattaa agtttatata cttaaatgat aattttttct
    25861 atctctaata taaaaaatat taaacataaa actaataact tagttaatgg aataactaaa
    25921 ttactgaaag gattaaaagt aaatggctaa aatacttctt ttagaagatg atgatacaat
    25981 tacatttgga ataaaaactt cccttgaaaa gaaaaatcac actgtatgtt gttataatac
    26041 gattgctgaa gctaaaaaaa attttgataa aactattgat ttaattctgc ttgatttaaa
    26101 tctacctgat ggtattggat acgagttttg ccaatatgtt aaaagtatag aagatactcc
    26161 agtgatattt ttgacagtcc gtgatgatga aaaagacatt atacgtggat tagatatggg
    26221 tgcagatgac tatgtggtta aaccgttttt gctctcagta cttcagtcca gaattaatgc
    26281 agttcttaga agaactcatt caaatactaa caatactatt acatgtgaaa atataagctt
    26341 gaataaggtt gaagtcaaag catatttaga taatgttgaa gtacctttga cagcaggaga
    26401 atataaactt cttctaagtc ttatggaaaa taaaaataga gctatgactc gtacaaagtt
    26461 actagaaatg ctctgggatg tagatggtaa tttcgtaaat gataacactc ttactgttac
    26521 aataaaacgt cttagagaaa aattaaaaaa tccaccttgt ataaaaacgt taagaggcat
    26581 aggatataga atggaggaca gctagtgaaa actccaagaa atatcaacag tacagttgtt
    26641 tttataatat tctgcttaat tgtaactttt ttattgagtg taattctaac aactataact
    26701 tcttttaatg aatacaatgt actgtctaag gctcttggtg catcatatga gtacaatcct
    26761 aagtctacag aaagtatact aaaatcactg aaaaattcta gtgataagga ttttaaaaca
    26821 ggaaatgaaa ttttatcaaa acatggatat tctaaaagta cattttggag taaaaacttt
    26881 ttttattttc tagtgatatc gtttggtata atttcaacaa tggctacagt tatatatata
    26941 atcaaacata gaacaaataa gcaaaaactg agtagaataa acaatcttac tcaatactta
    27001 gaagaagtga atttaggaaa agagtctgta cttttacgat gtgaagatga attttctcac
    27061 cttgaagatg agatatataa aacagttggg gaacttcgtt gttcaaaaga atttgcttta
    27121 aaagaaagac aaactctttc agataatctt gcagatattg ctcatcaact taagactcca
    27181 attacttcta tgtcacttat ggcacaatta ctttcagaaa attgtccaga tgaagaaata
    27241 gattatatta acagacttac aaatcaaatc tcaagacttg agagactagt ttcatcttta
    27301 cttacattat caaaattgga tgcaagtact ttaatatttg aaagcaaact tatagatgta
    27361 cattctcttc ttacttatgc aattgagcct atagaaggtt ctttaagaga aaaacatcag
    27421 acatttacta tcgaggcttc tccttcggta gaatttgaaa tcgatattaa ttggacttta
    27481 gaagctcttt taaatattct taaaaattgt agtgagcata tagaagatgg tggatatata
    27541 gttgcttatt atagtcaaaa tcctctatat gttgagatta tcatagaaga taatggtaag
    27601 gggtttgctc aggaagaact tccatatatt tttaatagat tttatcgtgg taaaaatgct
    27661 agtaaggaca gtattggtat agggcttgct ctatcaaagt ctattataga acgtcaaaat
    27721 ggtactctac atgcagaaaa ttgccataat ggtggtgcaa gattcataat taaattttac
    27781 acataaaatg ctggattata ggtaaaatac ctataatcca gctatatcta tattctatgt
    27841 tatctattgt tttagtaata tacttctatt tacatttaag gttttattaa acaaacaact
    27901 taactatccc tatacttgta agtagtctta aatcgaaacc tttaaataag ttcaaataga
    27961 ttttgtttat attgtttcat tttttataga ttctactata ttttcattct tcaactgctt
    28021 gtatcctgtc atatatgatg ctattacaat aaaaagtatc aatatagtaa aacctattat
    28081 tgtagatata ggtgcaaatg gtaaatactc tataaaatat atttcattta tacgtagaaa
    28141 agcatacact attcctattt gcacaggaat actaagtagt aatggtgtaa ttcctaagaa
    28201 taaaccttcc aaaataagca tcttttttat gccttctgga gataatccaa cagaacgcaa
    28261 catagcaaac tcttgtcgtc tacttctaat atttcctgac actgtagcaa gtacatttga
    28321 taatccaatc atagccaata aacctgtaat aaagcctact attaaattca tggtctttat
    28381 tccactagcc ttttgttttt cactttctaa aacatcctca atactataat ctcctgaacc
    28441 atagtcttta ttataaatgg actctaattt ttctcttact ctaggaatgt cctcacgatt
    28501 atttacttta aatactccta tcagcctatt tgaacgtaac ctacttactt catcataatt
    28561 tttagatatt tcctgtacca tagacattgg aactatttgc attaatgtat actttgaact
    28621 agtatctact attttaggaa gtgtgcttgt aatagctccc actttcatgt tgtaagtata
    28681 atccccttta tcttcgtcat atactttttc atttaattta atgttatctc ctattgaaag
    28741 atttaaataa tctatatata ctttatttct acgtgtacta cgattaatat cttcctcctt
    28801 attatataca attgaggttg gattttttgt attataaaat aactttgggt ctacagaaat
    28861 ttgcctacaa tattctgtaa aactcttatc atcaagccca attatatttg aaattatacg
    28921 aaacttgcca tcacgttcta taggagagta ttttttagat gaaactatac ttttaaatcc
    28981 tccatttttc gcaagttctt ttgatgcatc tttttcagtc agccaagtgg aagcagacat
    29041 tttttgataa tatagtgaac tttttacacc ttctgtatta tctaattttt caatgaaagc
    29101 agactctata ggttcactat tttccaaata aactgctata tctctttggt ccttataatt
    29161 atcacttcca taaacagctt ttgctccttc ttgatttgca attatatgca aaaaacatgt
    29221 aagtaataaa aaagataatg ttaaagatat tgttgcagta cgataagatt ttttacgagc
    29281 acgtagtgcg tttgatgcaa gttctccttc tattccaaat atctttccta atgaatattt
    29341 atgcgacttt ttgattttaa cactatctcc ttgtcgtatt gcttctatag gagatatctt
    29401 tgatactttt cgtgctggta taagtgcaga aatccagact gttactattg taagtaaaac
    29461 tgctggcaga aaagcaggaa taccataagt aaataccact tctggaacat cagtatgata
    29521 attaactgaa ttaacataaa ctataagcct attacacaat aaccatccta aaaataaacc
    29581 tattggtaat ggtataattg tcagtaaaaa gccttcaaac actacagacc ttttaatttg
    29641 ttttggtgat gcaccaacac tagataatat ccctaactga gtaagtctag catttgcaga
    29701 cagtgaaaac gcgttgtaaa tcaccattac aaacacggct actgtaaaaa ttgctattgt
    29761 aagatacata ataggagttg aaaattttga tatactactc atagatgctt tctgttctgg
    29821 tgaaaagact aacatcttta aaagataatt actattgtat ttaagattgt attttccata
    29881 ttcattagtc ttccatccca atgatttagc aagttttgga agttccttat acgtgtctct
    29941 tatattttta aatcgcaagt acacagttat actatcatta ggttttatac ttgttttatc
    30001 aagatatcca agagctgtat atgcaggtat tactgatgaa gtagaaacat ctacctttcc
    30061 tactattgtc aatgtagcct ctgaaatttt tttaaaactt tcccctttcg attttggggc
    30121 tatgggttca agaggctttc catttaagat tctatatcct attgggagag taattttatc
    30181 accaattttt acacttggat tattctcaaa atattgtttt gataatgcaa tttcattagc
    30241 attatttggt cgacgaccct ctattatagt atccttttct ggcatagaat tccaatactc
    30301 tgatgtagca tttctataaa ttatataatc tcttttctca tcattaattt tgcctacata
    30361 ccattgtcct tttaccatta catcatcaac tgaagaaaaa ttttcaatta atggtaagtc
    30421 acttccataa gtatagtcaa acaattcacc atgccagtta ccttctttct caattgaaag
    30481 tcttataaaa tctgtccaca tggtatacaa cagtccacac aaagaagaca tcatggttgt
    30541 agtaagtaat atagctaaca ttatagctat actactacgt ttattgcgtc gtacaaagtc
    30601 taaggtgtat tcttgaagaa tattcatttc ttcaccacct tttcagagac aatcactcca
    30661 tcttccatag ttacaatacg atttgcctct agtgctattt tctcatcatg agtaataaga
    30721 agtattgtct gattaaatcg tttatttgat aagtttaaca agtctacaat ttcttctgaa
    30781 ttttttctat caagattacc agttggctca tctgctaata aaatagctgg tctatagatt
    30841 aaacttctag ctatagatac cctttgttgt tgtccacctg aaagttgact tggaagatgg
    30901 tttaatctat cagataatcc caatatagat acaatctcag agaatctatc ctcatccacc
    30961 tttcttttat caagtaacat gggtaataat atattttttc taacatcaag ggtaggtata
    31021 agattataaa attgataaat aagacctact tttctacgtc taaaaactgc aagagcttct
    31081 tcctttaaac ttgatatttc tgtatcttca acataaatct ttccagatgt aggtctatct
    31141 actcccccaa gcagatgtaa caatgtagat ttgccagaac cagatgctcc tacaatggat
    31201 acaaaatcac ctttttgaac tgataaattt acattattaa gggctgtcac tctggtttga
    31261 tttgaaccat atatttttgt gagattttca cattttaata tttccatata caatcatctc
    31321 ctttatggtt aaattttagc aacctaaaat gacattatag tgacatgaat acaaatataa
    31381 attactatta aaaatattgt ttagtttttg cacattattt aaaattataa tataaaacaa
    31441 aaactatgca atatatttta tttatacttt taatatatta catagtcttt aaaaggtatt
    31501 aactttaaat ctataggtat tcaatttaat aatcaatagc aagtatttta tgtactaaag
    31561 gagttttgct ctatatagac tcaatttagt aaaattattt aataaatatt acagactata
    31621 ggtaaataat atttacaaat aaaattaagt ttattccctt acactataat atttcttaat
    31681 tatattaatt gcaatttcct ttacctttgg ccctgtaatt tctttattgg aatcatctga
    31741 tttaatagca aaataatagg tgtcaccttc acgctctagc ataccaacaa accatgcatc
    31801 cacacgttta tttttttcat caaatcctgt tccagttttt ccatatacat ttatgttttt
    31861 atcatttata tctattttca taatatctct taaaatatta atatgctctt ttttaaagtt
    31921 tgtatctccc tcaaatattt ttgccattgt ttgcacttgt tcttttggag atatttgtaa
    31981 tgaagattct aaccaaaatc catttaaatg tccctttcca ttttttaaat cgccttccca
    32041 ttcgctaata tcgcaattcc catactttaa atcatctaaa atgttttgga cagatttagc
    32101 atcaacttta tctatcaatt ttttgtaata ccaaacacaa gactccttaa atgcctcttc
    32161 taaactaaga tttttattcc aatttttatt tggatactct gtaccatcat atcccataac
    32221 tgattctttt gagtttatta cccctttttc taaaccaatt aaagttgaaa ctattttaaa
    32281 agtagaacat ggtgaccttc ttgtttcaat taattctttg ttatatatat tatattcttt
    32341 atttttagta ttataaaaaa tagctcctcc actaatacct tcaaaacaat cactatagtc
    32401 aaccatatta attttttctt ttttgttttt atcattgttt tcaattttgg atttatttaa
    32461 ttcagactta tttaattcag attttatata attcttatca gttttttgat ttatatcgtt
    32521 atgttttttc cctacataat acattaccat aactacacca accaataaga tagctatcca
    32581 aataaaattc ttttttcttt tcataattta tatcatctcc catatttaaa tttataacct
    32641 actattaaaa tagtagacat tatttgtaat atactccaat ctaggttcta cttataagaa
    32701 acaagactaa atgaatagct gtatctctta tattttcttc acctagtaca attatgttga
    32761 ttaaacctat tgcgaagata attaggtaac tattaataac atcctgtcct ccttttaatt
    32821 tgtgatataa taattgattc cacatttaaa acttactatt gtaatattta aatattacaa
    32881 tagtaagttt taaatgtcaa gttagtttag gaaagttatt ttaattgtat aattgttatt
    32941 acatttataa aatatggcat gtttaaaatt attttgctat tgggaggatt aagataagca
    33001 gtattataaa agctataaat tataaaattt aatatataat ttatagcttt tacttttaca
    33061 aatattgttt ttattgattt attaatgaat tttattgaca ggttatattt atataagtaa
    33121 acacttacat aataagtata taatctacat atctataagt tgagtcaatt cacaagtata
    33181 tgtcaactta agtttatgca tagctcgtgt acaggcaata tataacaaac tgcggtcata
    33241 atcactataa tatgttttat tatttactga aggtacaata acttcatcaa actctaaacc
    33301 ttttgacatt ttaatagaag ttatggatac tccttttgta aagctagaac tttcagaaga
    33361 tattaagtga acactatatt cttctcttaa cgcatcatat acagctttag cgtcattatc
    33421 tgtctttaat ataataccaa gagtcgcatt atcactcttt ttaaattctt caatttctat
    33481 ttttatctta tttatttcat cttgctcgtt attacatttt aataaagctg gttcttcacc
    33541 atgtcgttca ataggctcta atgaagatat gtcttgaatc tttttggcga aattaataat
    33601 ctcaaaagta gaacggtaac tcttgttcaa cataactaat tccccatcat tatatagctg
    33661 tttcatatca tctagtgtat gagtatgatt aggattaacc aattgtccaa aatctccaag
    33721 aatagtcttt ttacacttaa aaagtaagtt tattacagca tattgaatag gtgtataatc
    33781 ctgcatttca tcaataacaa tatgccttat aatcttatct tcttgtatac cttcatatgc
    33841 agcatgaata tatataaatg ggtatacatc tgaccattca agtgttttct tttctaccat
    33901 cacaaacatg tttgatatat tcatttgttt aaagaaatcc ttatatagtg taagagtatt
    33961 ttttattgtc aacattccat tcaaactttt aagtatactt tttacctttg gtaaatcttc
    34021 ttccataata ttatctgatt caaatttata atgaatgtct tcagctacat tctctaatct
    34081 cttcttaact ggatatctgt tatatgcctc aaatctactc tgtatccagt cacttttagc
    34141 tgtaaaactt ccaaaagtgt agtcttttgg aataaaaatc ttatttggca tttgttttat
    34201 ataatcatca ataagtttta caaaatcaag tgtagattta aaacgcactc tttcagacca
    34261 tttagcatca tttatttcta atgggtcttt ctcactttca aaattaataa ctctatctaa
    34321 ttgtacctct gctatatttt caaaacttaa ttcacataat ggttcttctc caagctcagg
    34381 aaggacattg gaaatatagt ctccaaagac tttattaggt gataggataa ttacattatt
    34441 tgctgatatt ttatctttaa atcgataaag aagaaaagca attctgtgta atgctataga
    34501 tgttttccca gaaccagcta ccccttgaat aatcagtgta tcagctttat catttctaat
    34561 aatttgattt tgttcctttt gtattgttga aatgattgac ttcatttttt catctgaagt
    34621 gtgactaagt tctttttgaa gaatatcatc ttgtatatta atggaacttt ctagtgcata
    34681 ttctaatttt ccatttttaa ttttaaattg tcgttttctt gttatttctc catccaccca
    34741 tcctattgga gcatcatatc cagcttttcc gatttcataa tcataaaaca tactggcaat
    34801 tggagaacgc cagtcaagta ttataagctc atcttcataa tcaaatgcaa atctaccaat
    34861 ataatactta gattcatcat ccatatcttt cagcctaaaa tctattctag caaagtatgg
    34921 agaatctttg attttattaa tcttatctcg aacttttacc ataaaagccc catagttatc
    34981 tatttgtttt agtccttgtt cattttgaaa catttcatgt gggtctattt caccacgatt
    35041 ttttaccata tacattttag cgtccatata atccttatca agcttgtcaa caagattttc
    35101 agctttctta aaagcattgt ctagcttgtt atttatctct attagatgtg caatctcatc
    35161 tggaaaaaaa gttaataact ctgcatcata ttcacacata ttatgtttag aattagatgc
    35221 aataatatcg caatttacta cttgtttatt ttcagacatt taaatcctcc tttgttaatt
    35281 aagtacttac actgaatcat tatacttaat tgtgttttgg agtttttaat cattcttgct
    35341 atttaactta aaggaagaat aaatttttga gtaggatatc caaattccac aagcaactct
    35401 gcttctgcaa agcccaactt ctttatcata tctctatgtc ctgtatcagc tttgtcaccc
    35461 tctcgaaagg tagtaattga aatatctgta tctatcaaga aatcttcaat aactttcttc
    35521 aaaaacactt gtgcaatgtc tgaattacga tactgtggat gtattccaaa aaaatcaata
    35581 cttctagttt ctctattaaa caccatattt gcaatagcga cattattaag ttttaatatt
    35641 aaagctcttt cttctaaaat atactgttct aattgatata tatattcttc ctcttgcaaa
    35701 tttggaaatc catctatgac taatctcact aaattcatcc ataatggtat gtcagacata
    35761 cttgcaagtt taatttcttt ttccaactct agtacattct ttgaaaatag gttatctttt
    35821 ttcaaaacaa atcttagctg caaaggataa aattcttgtt ctttcctata tttatttgga
    35881 gattttttat acatagcttt aaatatagaa gtgaatgcct gttgactttc atatccagct
    35941 atcaatgcaa tttcaataat tggtttcttt gaaaatacca ataattttgc tgcttctgtc
    36001 aactttctcc gctttatgta atcatgcatt gttagaccaa cagaagttgt gaaagttcta
    36061 tgcaggtgat attttgagta atgaacagca ttagcaacta tatctaaatc cagcttttct
    36121 gataaatgct cctctatata gtcaatagca gttatgacat taattacttt gtaagacatt
    36181 gcagcttccc tccttttatc catgcaacat tatatcaatt attacttagt tatatttaat
    36241 gaatcttgct attttataaa caaatttgtt gtttaagttt tcaattcata aatttaatat
    36301 attacttttt actttctgat taaagactct aatcctttaa ttttcaataa tttttcattt
    36361 agtaaatcta aaaagttatt tattattttc ttcttattag attcctttta gattccttaa
    36421 ttaaatgata aatatttata ttatacgact aaaaacagct ttttacaatt atttaatatg
    36481 attacaaact taccctatct taaagtttaa tggggtcctg ttatgaatct ttttatttta
    36541 atttaagctc ttcatcagtt tgttttatat attgatgtat ttgatttcat acaaaaaaga
    36601 gtgcttcatg aactaaaaag ttcattttta aacactctct tttatgtaaa taaatttcta
    36661 ttctattttg aaatattata atttgactta taatctgtta ataccaaaaa taataaattg
    36721 tacgtctaag aatagattct aattagttgc tcagtagtaa aatctgtttt taactaatcc
    36781 tgctttgtat gttgaacata ttctataatt gtaccatctg gatgtctcaa tgtcatatta
    36841 tatcctgtag gaactttttt cttatctctt actacaactg ctccattatc caatagataa
    36901 cttctccatt catcaacaga atcaaccata aaagtagatt ttgtttctat aaatggttta
    36961 agagcatcat cagaaccaga taatagtaaa acatttccta tttgcgctaa ttccaaccca
    37021 acttctttat aggaaaaacg caaagaacat ttttctttta aaagattctc ataaaaaggt
    37081 atggcttttt ctatatcttg aatataaaaa cgtgttaata tatcatatat tttcatattt
    37141 tccccctata tatctatata atattacctc taaattatac cactctacaa attatataac
    37201 aataaattaa gcatagcctt ttgagcatct taagtagacc ttaacaatat attggggtta
    37261 cattagaata cataaattaa atcaccttga tattatttag gataaaattt atgtagtagc
    37321 agtaaatgtt cttctaatta tcaactaaca aacgataatc tttaactttc tatataatgg
    37381 gtaacatcat tttcgtaaga tattcactag ctggacgatt gatatcattt aaatactggt
    37441 aatatatatc gccatgaagt ttatatccat tgctatttgc ccatgaaaat aagtcttcta
    37501 aagtagggtc ttgtaattca taaggtccta aatcaattgc agttattatt ttctgtgcag
    37561 gaacaatctt ttgtagaatc tcatttttcc catctatata agtggctaca ggaaacccta
    37621 cttcaacatc caattttact aaatccatgt tatgaaaaca tacaatcggt gctcctgaag
    37681 ataaaattcc tctctcctcc agatatttag aaattttttc aaaactttgt tttgaaaact
    37741 ctgaaaattc taccataaag tcaattgttt ttcgtattgc caaaaaacag tactcagatt
    37801 gttcagctat tgttatattg gatattctag tcattttatt cctccattac tttattttca
    37861 tttctaatct ttttatacca aattatacga aaattcactg tgtaactaat tatttcatat
    37921 gaatataaaa cataacctcc ttccatttct tatatcgaaa gtatagcaaa aataatctca
    37981 tcattcttgt cacacagtgc tcttataatc agaacatact taaaagactt gcctaatttt
    38041 taggcaagtc taaaagaaat ctttttctat aaaaaattta tacaaacaat taaaatatca
    38101 aaatatagac taatataaaa ctataaattt actaatctga acctcccatg gctaaagtca
    38161 caagattact gatttataga atttcgcaca ctaaaatatg tcttactaat tccccacagg
    38221 ctacccccct agttcctacg ttcttacata agttatctat tatcaaacat caaaatttaa
    38281 acaagtttca ggttcatctt ctattcttgc tattttaaac ttacatgcaa ttaatactaa
    38341 agatactatt ggatttataa tatttaataa agcgtatgga ccatatgtta gtgcagatac
    38401 acctaatgtt gctgttatat acgccccgca tgtattccat ggtactaatg gagaagttaa
    38461 agttccacta tcttctaaag ctctcgacaa catcttagga tgtatacctc tctttttata
    38521 ttccttatta tacattcttc ctggtataac tatagataga tattgttcac ctgctattat
    38581 attggtaatt gtacaagtta ccatagtaca taatactgtt ccaaatacac cctttgctaa
    38641 tcttagtaaa gaagatgcta ctacttcaag catacctgtt ttttctaaaa tacctccaag
    38701 agataaagcg catattgtta aggatacagt ggacatcata ttcataatcc cacctttaga
    38761 taataaagca tctacctcct gtatttgtgt tgacgaaaca tatccatttt gtgctgcatc
    38821 taatatcgta ttcatagatt ctccttgaaa aactactgca aacaatactc ccaatacagc
    38881 acctactata agccctggta tagcaggaac tttaaataca accaatccaa ttactattgc
    38941 tggagctaat aataatactg gtgataaagt attaaatgta gaatctaatg tagacctaat
    39001 taattctatt tgttttatat ctagtgcttg acctgaatac ttcattccaa ttacaccata
    39061 aattactaaa caaattaata atgatggtat agtcgaatat agcatatatt ttatatgtgt
    39121 aaacaaatct gttcctgcca ttgctggagc taagttagtc gtttcagata aaggtgatag
    39181 tttatctcca aagtaagctc cagatattat agaacctacg attaatccaa ttggcatacc
    39241 taaactttga ccaattccta aaagagctac tcctactgta cccattgtgc tccaagatga
    39301 acctgtcgca agagatacta ttgcacagac taatgttgat gctactaaaa aaatatttgg
    39361 tgataaaatt tttagtcccc agtaaatcat acatggaact actccactta ctatccaagt
    39421 tcctataagt acgcctatta taattatgat taagattgct tgcattgcca tctttatact
    39481 attaaacata cttaattcta actctttcca tttaaatcca agtctatata cagccacaag
    39541 tcctgctact gctgctgctc ctattagtgg tacatgaggt gatgaaccat acactaatac
    39601 tcctagactt aaaaataata tcaaacaagt aattggtatc attgcatcaa acagacttgc
    39661 ttttctacat tctcgctctt tcataaaata gtttcctcct aattatttaa acactacact
    39721 ataatttttt ttgaaacata tttgctcgta ctagatgaca tgataccccc ataagttaat
    39781 aaaaattcta aattgtcacc taatttataa tcatattttg tgttacttac atctagtatc
    39841 atgtggtctg aacttgcccc taatattttt atatcagtgt ctattggaat taaagagtca
    39901 atatttatat cttgtttacc tatagctatg attgcccttt ttaagattcc cttatcttca
    39961 taaacaggtt tatttctaaa ggcatcaact cctatttctc caataggaac tgatggtttt
    40021 tctttacatt caactacttg gcatattaat ttaaatgcat cttgatatgt tccatttata
    40081 ttttcaccgt atgccgtttc tctaccaagt agaatggact cgcctattct caaattagta
    40141 ataccttctg gcatattatt atttatcaac agatgaatag aacttgaatt acctccagat
    40201 actatttcta gatttattcc aaatttttct tccattcttt ttgctatact taccagtctg
    40261 cctatatttt ccctagatgg tataatagct ccataacagg ttaagtttgt agctatacca
    40321 attatttcaa tattttttaa tcttactatc tctcttacat tattaaaaaa gtcttcttca
    40381 taaaagtatc cttctcgtaa atcgcctaag tcaaacataa gaactatctt atgaataata
    40441 tttttacttt cacataattc atttaatttc tttattgttc ctaattctga gttaaaacta
    40501 atatcgcaat aattgataac ttcttctaat tcacttaaca ttgggattct aatcaatatc
    40561 ttaggtagat ttatatcttg taaatttttt aagttttgta ttcttgaatc tgctatatgg
    40621 tctattcctt cactacatat ttcttctact atttcttttt gtgcacaaaa tgatttagta
    40681 acaaaagata tcttaatatt tctttcatga cacatctgcg aaattaattt tgcattatgc
    40741 tttaactttt ctatatctat ttctaaccta ggatacataa tctttcctcc tcaaaattca
    40801 aactttttaa caggagctta agagatgctt cttcatattt tttagataaa acacccatag
    40861 atgccataat atagtcatta tctattaata tctttgtttt ttcctttgga aatagtaatt
    40921 cattattttt attgtatttg agcatattat ctaatatttc aattctacta gggagcctag
    40981 taagtgctcc ccctgtacca actatatatc ttacttctgt taaatctttc ccttctgcaa
    41041 ttttgacttt tccagttgtt ccatagatat ttcttatttt tcctgaatgt cttagcatag
    41101 ctttaacaac agcttctttt gtcaatcttt caacaaataa tatttcttct tttgattttg
    41161 gtattggagg ataattctct attactgcat caatatctat agatagttca ctttgtaagt
    41221 tttctttacc tataacttct actatattct tcatatttac atatacacct aaatccccct
    41281 caacacttct ctttgcagta ggttcaggat taaccaaaat tttattaata tagtcacttc
    41341 catctgtaac agaatgtaca tcagtagttg ctccacctac atccagagtt aataaatctc
    41401 caatattttt atataaaagt ttagaagctt ccattacagc tcctggagtt ggagtaatat
    41461 tttcattaac catttcttta atgtatttca ttcctggtgc tgtagttatg tgttcttcaa
    41521 atacactttg aatgattctt cttgtaggtt ctatattcaa taaatctatt ttagggtata
    41581 cattttcagt tatataaagc ttataattag tatcttcaaa tattaacctt atttcctctt
    41641 gattttcaac attaccagca tatataactg gtatgcctag attcatagaa gctatcattt
    41701 ctgcattata aatagctgta tctctttctc cataatcgac tccaccagct attaaaatta
    41761 tgtttgggtt tatttctttt attttattta aatcagttct tttaattcta cctgatgtta
    41821 tttgacgaat aacagctcca gcccctaaag ctgcttcttt agctgctttt actgtcatat
    41881 catagactaa tccatgaaca gtcattttta atccaccagc tgcactagaa gttgcaaaca
    41941 tatcattata ctttatatca tctacagata atttattagc taaatcttta atagcacctg
    42001 ataagccatt tcttacatcg ccaccttcaa acactgttgt tggagcttga ccttgaccca
    42061 aaaatatagg attgttagta ttaatatcgt ggaaagcgtt taccactgta gtagtacttc
    42121 caatttcagc taccaacaca tctattttta aagaaacctt gctattttcc attatttatt
    42181 actcatttct cttctttttt caactaagaa agtggctaca tgtatgcctt tgctgtttct
    42241 tccaaatcca gcatctatgc cttgttcaac agctatttca ggtgttactt gtgttcctcc
    42301 acacgcaatc attactttat ctcttatacc tttttctaca caataatcgt gtaatttttt
    42361 catgttttta tagtgaatat catcatgact tattattgta gatgcaagta ttgcatctgc
    42421 attcagttca atcgctgcat ctaccaattt ttctacaggt acagaagtcc ctagatagtg
    42481 gcattctatg ccatattttt caatacctcc atgttttata tctattattt ctcttaaacc
    42541 aactgaatgt tcatcttctc caaccgtagc tgaaactatt ttcataggtt tttcttctat
    42601 atctgctctt atttcttcat cagttagtac cttaggttct tctggtatta ctaaattgtt
    42661 taaatctata tcaaacggaa ctcttccttt cacttctatt ctagtccctt cagattcatg
    42721 cataacttct ctacttatga cctcaatttc ttgtaagttc atttttttga caaattccaa
    42781 agctgcaaac tctgctgttc ttttatcagt aggaagcatc attgttatca ttacaattcc
    42841 atctgcacac cattccattt caggcttaat tttagttcca tttctgtact catatgattc
    42901 ttttagtcta ttttctacat tatcaaaatc gtcaagctca tcaatatata ttattttgtc
    42961 tggattttca aatgtacatc catctattaa cattgatgga ttatctatag cattttcatc
    43021 atattgagct acattattgt atccaaagtg agcagttaca ggtgctaaat aatcttcttc
    43081 tctttcataa acagtacctt caccaactcc accttttatt tttctagata ttccatcacc
    43141 atttctttct ggataatttc cagaatcaac aaaaaatcct tgttccacag attcaaaata
    43201 tccaccaact tcagatattt cttccatata taatacagct ctttctttaa gttctcttgc
    43261 tttgtctctt aattcaccga catctttaag ttctatcata tccataagcc catccatacc
    43321 aactaaagct tgctttgctg tatcacatgc ttctatattg tatatatgcc aaggtacatt
    43381 tctaccttca tcaggtgtta tagttgattg tatgtcagct ctagttaata ctgatgttaa
    43441 taagtttaat acatgagtaa ctgttgcttc tctagttgat gattccatat atttagtatt
    43501 catttgagct ctcatcttat aatcactaaa taactctcta agtgcaaccg cgtaaggtaa
    43561 gtctattttt aaacatggtg ctggaggtgc tgttggtgga actgttgata agcatatatt
    43621 acttttatct atacctattt tttctgagaa tatagagttt aaagcgtgtt gaaccataag
    43681 ttcaggcatt accttccatg cttctctagc agtagcatta gcattatgtg ctccatcaat
    43741 ttgagctata ttggcaaaag ccattatttt ctttgcctca caagcatcta caaaagacct
    43801 taccatgttt atattcctat acagaacatt atattgtggg tcttgatgtg ctccattgac
    43861 tccttcctca gcaaacatta ctgctacttc aggaccagca acaccactta catatgaatg
    43921 gtaattaata ggtctaccaa cttcttcttc tataaaatca agagccttcc tttgagctct
    43981 tacttgtttt cttgttattg gaactccacc tataccttgt ggagttcctt ctataagccc
    44041 atcaaaatgt gattgtccag cagttctgat aaccattaga tggtcagctc catgatgagc
    44101 tgccattctc attcttctta tatcatcctc aaatctacca gaagctattt cagtagtaat
    44161 aactggactt ggttgagggt ctatattatt gaaatactta gatgatggta gccctacact
    44221 cttctttaaa ggttttgtac agtctttata tttaaaaggt cccatttcaa gattttccaa
    44281 gtgttctctc caaacccaac ctcttcgttt tggtttatat ttatccaaat cttttaatat
    44341 atagtctata tccaattttt tattttcctt taacatgatt ctaccccttc tctaaataaa
    44401 catgtaactt catcccaata ttcaccctta actaataaca aacctgcttc tctaaccgtt
    44461 atatttttag atttagccaa tttataaact acatgccctg ctcctttacc tataagacct
    44521 ctttccataa ccccttctaa aataggtttt acttcaagag aagaaaatcc cattctcaac
    44581 aagacagacc tttctattga tggtgttgta ttctttttac caagttctat cattggttct
    44641 actatctggg tagctaaact ccaaaacctt tcttttaact catcatcact cagttcttga
    44701 agatgttttc ttctaacttc aaaatcatcc tctctttttt tcatgaacat tcctccattc
    44761 gtattgattt aatcgaattt tctgaatttt tattttatat taaattaaaa aacaataatt
    44821 actataaatt atttaataca tcaacaacaa aatctcttga actttttact tcttccatta
    44881 aaaattctat atctcgatta cttagcttat caatattatc aatgtgatta ttagatatac
    44941 aattttttat aaatgacttt cttattttat tcatatcaat atcaacacat ttcaataatt
    45001 ctggtctttc tggtaatatt aagtttactc ctgcaatttc ttctcttgga tttccaaatt
    45061 ttatatctat tccattttct cttgcaaagg taagttgtgg acatatatgt ttacctgcac
    45121 ccgtatattc tgtttcttgt accactatag ctttatcctc atctagctct tgagctaaag
    45181 agaatgctgc tgctaaagat gtatttcctg ctggacctct ttctatacct tctagctgtg
    45241 ccaataattc agttgtataa aaaacttctc cttgttttac taatacatat ctatccatat
    45301 atctaagtgg tctagctgca gacctaggta catctgacct atcaggccat gtacagtatg
    45361 gtatcccaaa acctgtatgt cctgttgtaa atgatttttt attaaattga ttatcactag
    45421 ccatgtgtaa tccttttaaa tctacacttg ctcctactac tttagtatta atagaaccag
    45481 cttttatcaa tcctcttgca gttccagtaa gattaccacc acctgcattt gtacaaacaa
    45541 ctatatcagg gtctttttta tacttttctc taaattggat agctaactca taacctaaag
    45601 tttctacacc tgcaattcca aatggtgaat ataatgatgc gttaaaatag cctgtttctt
    45661 ctaataaaac taagaacgta taaaataact ctggtccaac agttaactga acaacttctg
    45721 ctccatatgc ctcacatttt cgcgcttttt ctatgatttc aggttgacct acaccattag
    45781 aatcataaca ttcttgaact attatacatt ttaatccctg cattgccgct tgtgatgcta
    45841 cagctgcacc atagttacca ctagtagctg ctattacacc tttatatccc atttgtttgg
    45901 catgatatac tgcagtagct gctcttcttg ctttaaaact accagatgca ttcattgctt
    45961 catcttttac aaatattcta gctcctttac cttctttagc acattttcta gctaatttag
    46021 tcaaattttt aagctctatt aaaggagtat ttccaacagc atactgtgat tgaattgctt
    46081 caatatcttg taatgtatat cctgtttcac tcatcatttt ctcataatca aaccctattc
    46141 cctcttgttc aaaagaagaa taatccaatc cgattgcatt tttcattatt tcgttatttc
    46201 ttcccataac agcttgataa ctcatatctt tcattgatgt tgaattattc attatataca
    46261 cctccaaata atatttcttt agcttggatt cctatttgga gtaactctgg tatacattta
    46321 ccataatcat gagtataata tggatttatt ttaagtaaat taccttttac aagtctgcct
    46381 gtaattgttt taacttctac taagtcgcct atagaagcat cactttgtat aaaaccttta
    46441 acccacattt ctaaggatac tttcttagta tcctctggaa cttgtggagc tctttcttct
    46501 ggagtcaata ctatattgtg tataataacc caatcattaa ttttagcatc cattttttca
    46561 tccccttatt aattgactat tgccttacta attaatttac tgttatttta aattaaacat
    46621 tattttacca attagctaac tgttatctta ctaattagct agttgctatc ttactaatta
    46681 gcctttgatt cttcttccaa ttcaacttct atctgatttc ttatatctcc cattattgct
    46741 ctaggtactg gtatatccaa catagtttta agacctggtc tagcatttat tattaatgga
    46801 atagagttta ctatcattgc ataagtacct actcctccag gtatttcagg atttatttgt
    46861 aaatcaatgt ttggtatacc ttttattgat acatagtctc ctgttttaat accttctgct
    46921 tctggtatta tctgttgtgg atgctccatt tcaattaaaa cttctccatt tacatatcca
    46981 tatccacatt gtctacaacc agcaacattt ccagccaatg cctctccgta cttagatttt
    47041 ctatctactg tagtcattat tggctctttt gtttgttcta tcttatctaa tttccaacct
    47101 aatccatcag ctatcatatt tattgattct acaaaaccta catgacctgc tatagtctta
    47161 tcttctacac cttttataaa ttcttccctt gttactccaa caccttgttc caccataaca
    47221 gactttccaa atggagataa atcatttact ctcttagctt ttatactagt aacttcttca
    47281 caagtacctg aaagtgccaa tactagtaaa tctaatacaa atcctggatt tattcctgtt
    47341 ccaagtatac ttactccatt ttcctttgca acttcatcca tttttttagc taaatctgca
    47401 tcatcagctt gtggatatgc catttgttct gctgttgata taacatttat ttttctattt
    47461 aataagaaat ttattttatc aaaagccttt ttagtaaatg aatcagttgc taacaaaaca
    47521 acatctacac ttttttctct aaaaacttct tcataatttt tattgataat aacttctggt
    47581 ctttctcctc tttcaattcc taaaacatca tacatacttt tccctgaagt acttctacta
    47641 caaacagata ctatttctat accttctttc tttagaatca tattagccat acctattccc
    47701 atagctccaa atccccatat tcctactctt acttttctca tatatacacc ctcctaaaaa
    47761 tttatatatt ctcaataatt agttaaagca taaatcgtgc caactttaaa attaaagtaa
    47821 atatttattg gaacgttgaa actataatta ttttattatg tattttcata aataaaaaat
    47881 aatatttctt atgagaaata aaaaaaagag caaaatattt tgctctttta taataatttt
    47941 gctcctctat tttgcttttt tattttactt tgattttgtt tttttatctt gcttatttat
    48001 aatattttga tattatattt ttttatttta tactgtaaat tttgcctatt catacctaaa
    48061 attgatgcag ctttagttat attgtaagat gccttttcta atgattcata tatatacttt
    48121 tcttctatct cactgataat cttactaagt gttttgtcct ccaaatcgtt taaagaataa
    48181 ttgttactct ctttattctc tttaagattg taatagtcgt ttagattaat catacttgtt
    48241 tctatttgta cctcatcttc catcatactc atagtacaat aaattatgtt ttctagctct
    48301 cttatgttac cttgccaatc gtaatttttt aaaattttaa tagcttcatc tgaaattcct
    48361 accacttttt tatttaactt tttattatac tttgaaataa attttttgca caatagaggt
    48421 atgtcctctt ttctatctct aagaggagga atttttatat gaattatgtt aagcctataa
    48481 tataaatctt ttcgcatttt atgctcgttt aaaattacct ttggactttc atttgtcgtt
    48541 gcaataattc ttacatctat aggtatatcc ttagttcctc caacccttct tacataacct
    48601 tcttgtaaaa cccttaatag tttagcctgt aacataatag gcatggaatt tatctcatcc
    48661 aataacaatg tccctttgtt agcttgttca aataagcctg gcctatctat tgctcctgta
    48721 aatcctccct tgctagttcc aaaaaggata ccttcgaata gtgattccgg caaagctgca
    48781 caattttgtg ctataaatgg atagtttctc ctattacttc cataatgaat ggactggcta
    48841 aataactctt tacccgttcc agtttcaccg tatataaata ctgaagcatc agacttgcaa
    48901 gctttcttag atttttctat tgcttcttta atcaaattac tttcccctaa aatatcatca
    48961 aattcataac cctttttttg tctactacta actttattga ctaaattttt tttataattt
    49021 ctatttagta aattttctat cgttgtcata ttctttgata tttcaagtgc ccctacaaac
    49081 tcgcctttaa tatcaattgg tattgtagta ttaattgctg ttatctcttt tccattttta
    49141 tccagatatt tttgaatatt gtctttgata acttcccttt tttccaaaac ttctaatagt
    49201 gtactcctgt ttattttcat tttgttgact atatcaaaaa atgaattggc taaaatatcg
    49261 tgtctgttca ttttttccat tttttgtaca gaattattgt agattatagt tttcccgtct
    49321 ttattaacaa aatgtacccc ttcatcaata ttttccaata tttcattcat tattttaaaa
    49381 aatatctctt ggttcaacta tatcacccca gtacctaaat atataaaaac ccaaaaaatt
    49441 aataaaatgt tgctattgta tttatcttat catatattta tgatattttt tatgtacatt
    49501 atattaatat atttttaagt atatttaaaa ttttatttat atatctttca ttatggttat
    49561 atacaatatt tgaattgtca ttaaatatgc caatagtttt atatattatt gattttatta
    49621 aaaaaagaga tatacaaact aataagttgt aatctctttt aaactctaaa ttagaattac
    49681 tctaatatat aacttacaat ataatccaat gtcctgttta tagtaaaaac cacatttaaa
    49741 ttttagattg gatgaaaatt attaagatta tttataaact caaattgcta ctctcctttt
    49801 tcttattatc ttttgaatgt attctttagt taaaaagttt tactttctca tatattataa
    49861 aggaaaataa ttttttacaa ataatccact taatagcatc cttactttaa acctaaagtt
    49921 cctctattcc aatttctttt aagtattcat acacaccatt ataaaaattt ggttgcattg
    49981 taatatcact ctcatcacct attggaacaa atataataaa gccttgcctt gcccttgtaa
    50041 gaagaactct atatgcattt tttaagtata gtatattatc ttctttattg atgttctgcc
    50101 atttagttcc attgaagtta tagtattcaa aatggttatt cttaaatctt aagttcccat
    50161 cccaacagac aattgtccag tctaactcta aaccttggat atcaaactct gttgcagttt
    50221 cttctaaaaa atatgaagct cgtacatcat ccttaccatt aagaaaccag tttgtagcat
    50281 caattttatt ttgtacccac actccatact ttcgaagccg tttagctcca gaacttgcag
    50341 tcattccata acgctgtgaa cctttcgatt tatctctcac ccacttttta gctaattcca
    50401 aatccctagt aacacatata gggtaatctt ttttaaattg attatataat tcctttgcag
    50461 caactttatc tacatctaaa acagctttaa caaaggttga tacattttca cttctaaaag
    50521 aacgtaacga tacagataag tgcaaatcat caattattct ataattaaca ccttctgtta
    50581 actcatcaaa agaattacct ttagaatatt cttcatcaat aattttattt gatatgtaaa
    50641 catcccaatc agaataatta tttcttagtg attcaaacca acctgatatt ccatctgact
    50701 cacctttatt tatctcttga cctccaccaa tcaaacaaac aatagtcgcc catcctatat
    50761 gacgatttaa aatactaata agaaattcag gctctgacat attaaagtct aatacacctt
    50821 tttttatttt cataaagtta gtcaaattag gttcatccca cgcacgttgt gcttcatcaa
    50881 aaattgtgac tctttcaata ggtggtgtat caacagatat agcttcatct ctaaaatgat
    50941 gaattatctg aataaattct ttcgcttttc gaatcgcttc agattttcgt attccatttc
    51001 tggttacatc atcacgagct agtgcttctt gtaaaacatc aactaatgga ccatttccag
    51061 aaaggaagac tgcatgttca ttttcatcta ctttttgtcg ctcaatggca atattaaggc
    51121 cagcaagtgt tttaccggct cctggaactc ctgtgataaa acatattgat tttctgttat
    51181 gagtcttact atagtctata attttattta tagctttagt tgtttgattt aaatttttag
    51241 cacttgcatc atttcttgaa atatcttcaa cattatggcc catatataaa gcttgtgcag
    51301 cttcaataat tgttggagtt ggcatgtata acgagtttat ccaagtgtct gaattaaata
    51361 aacttctatt atatgtagta caaatcttct ttatgtattt tcctatatta aactcattac
    51421 aacaataagt ttctaaaata ttttccttca tcattcttat tctttggtct ttttgagggg
    51481 cttttgtaca aataagtatt ggtactaaaa gtttatcatg actttctttg tgaaaacaat
    51541 taaggtcaag ggcatagtct gtaacttgtt caattgcatg cctaggataa gtgtcttcat
    51601 caactttaaa ttcaaggaga aaaacaatgc ccttgtaaat taacacattg tcaattctac
    51661 tgcctattcg tggtattgta tactcaaata ataagtgtcc atctttgaaa gttgagagct
    51721 ctctttttaa tattccaatt tcctttttcc atgtattctt ttgtaagtca tcagccgcaa
    51781 attgatcatt acacgttatc tcaccaaata tagtaaaaat atctttgact ataaattcat
    51841 ttacactact tgaataatat gctcttttca tacatcttcc ccctttatat ctaatattca
    51901 ttttatagcc tacatctatc ctacagtcta aaacttgact cctatacttt ataaatacac
    51961 tacatagata tgtttatgta tggtactttg ataataattt ttctttgcta agtacattat
    52021 aaactattta gttaatatgt tttttccata tatgcttatt atattataaa atggatagcg
    52081 catcatttaa atcattgatt aaatcttcac tattttcaag acctaaactt attctaattg
    52141 tgtatggtga cacatttaat gctttggctt gttctaaagt catttcattt aatatagcta
    52201 tatttggagc aaatactaaa ctttcatggc ctccccaact cactcctatt ttaaataaat
    52261 ctaatttatt tacaaatttt ttaacatcat ttacatcctt tgcgtctatt tcaaaactta
    52321 ataacgcagt ataattaagc aactgtttct ttgctagttc tttttgatta aaatatttag
    52381 ataatggatg atatacctta gtaactgctg aatgattatc taaaaattca actacttcct
    52441 tagcattttt ggtatgtact gataatctag cgtgtaaact tctcaaacct cttataacta
    52501 aaaatgcttc aaatggtgct aattttgcac catataaagc taattcactc cctcttattt
    52561 cttctatatc ttttttactt ccaataatac atccacctac cacatctgaa tgtccattta
    52621 aatatttaga taaagaatga acttctaaat caattcccat ctcaatacat ctttgatata
    52681 atggtgtagc ccaagtatta tctattactg tttttatatt gtgtgttttt gctagtgcta
    52741 caattgcctt tatatcttgc attttaaata ctgctgttga tggacactct aggtatatta
    52801 aagttgtatt ttgttttata gcattttcaa aatcttctat tctatcacct tcaactattg
    52861 tattttctat atttcctttc tccttcaatt ccttcgttat aaagttcatt gtaggattgt
    52921 ataaattatt tgaagctatt atatggtcac cattttttac aaaatgaagt atagcacttg
    52981 atatagcacc cattcctgaa ccaaaggtta tacttgcttc agcattagct aatgcagata
    53041 actttgcttc taaaatatca ttagtaggat ttttagttct tgaataaaga tatccatctt
    53101 ttgaaccttc aaaatatgct tctatatctt catatgtact tcttgcgaat attgatgatt
    53161 gatatatagg tgggtttaca gctccataat cgccatccaa attttctcct acatgattca
    53221 ttaatgtctc tatcttatat ttatttttat ccatgttcta aatctcctta tgaaatattt
    53281 ttatatatga aaaatacatt taacatagct tattttttat aagctatgtt aggtaataaa
    53341 gttaaaatat tcattatgat actttattag attgtttttt atcctttgaa tttttatatg
    53401 tacctatccc tgtaactgct aagattactg ctataattgg agttccccag ttcactatag
    53461 accaaagtgc gtattctcca acattaactc ctagtgtctg agtgaaaaat attgctgctg
    53521 gtgtccaagg aaataaaact tctaacaatg tacctgtatc ttctgtagtt cttgatagta
    53581 ccctacgatc tatattattc tcatcatatt tatctccaaa tatacctgct gttacaaaac
    53641 tacatgctat accatttgca gtcattgcta tcattgctat tcctgttaat aatgaagaac
    53701 atattatagc cgttctagac ttaacccacc caaatatcac atttaccgtt gctggcatag
    53761 catcaatact tccaagtact ccaacaacaa ataatataga tgttgatatt ggcaataatt
    53821 tacctaattc ccagaagcca cctttttgga aaaaacctaa tatataagct tgtccttcta
    53881 taggttttgc atattcatgc caagttacca tatctagtga gaatccactg ttaagtccta
    53941 taagaatatc tgccaaagaa aaaccttgaa agattactgc aaatgcaagt gataaaaatg
    54001 ctgctattgt cattactggt attgcaggtt ttttcattgc tgaacctact aatactatta
    54061 aaagaggtat aaataaaatt atattgaaat tgaacattcc tgataaatct gccaataatc
    54121 tagttatttc tggactattt aaatttgtat ttgttgctgg gaatataaac ccacaagcaa
    54181 tatatataac taaagctatt atagttgctg gacctgttgt ccataacata gatgcaacat
    54241 ggtcatataa attaactttt gacgctattg cagctatatt tgttgtatct gataggggtg
    54301 acattttatc accaaagtaa gctccaccta ctatagcacc tgctataata gcattgtttg
    54361 ctcctattgc attacctacc cccatcatta caactcctat agttgctgct gatccccagg
    54421 aagttcctgt aaatgaagaa aacaatgctg acaatattaa tgctgtagca tatacaaatc
    54481 ttggatttat caatttaact ccataatata ctaacatagg cattaatcca ctcataataa
    54541 atcctgcaat aagtggacct attactaata atattattaa tcctggtaaa gctcctttta
    54601 caccatctaa tccactttca aatacttctt cccacgtttt atttgttgta accactataa
    54661 atagcgatat tattgatgct gaaataaaca ttattgactc tattggcaaa ctatattccg
    54721 gcttattgtt aatcattgga agtaatagcc cacaaaataa aactgccata aacaaaacta
    54781 tagatatagc ctgcttttga attgtaactt ctctcttcat ttattatttc ctcccacttt
    54841 tatttactca ttaattcaat ttttaataac gttttccctt atctaacaat aaaatttact
    54901 atcttatatt
//
LOCUS       DAEPXW010000013        53087 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.013, whole genome shotgun sequence.
ACCESSION   DAEPXW010000013 DAEPXW010000000
VERSION     DAEPXW010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53087
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.013"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            134..1300
                     /locus_tag="KRM55_000778"
     CDS             134..1300
                     /locus_tag="KRM55_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBH1593035.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            1322..2968
                     /locus_tag="KRM55_000779"
     CDS             1322..2968
                     /locus_tag="KRM55_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBH1593036.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMRWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            3065..4438
                     /locus_tag="KRM55_000780"
     CDS             3065..4438
                     /locus_tag="KRM55_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1593037.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWAKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGSINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQDYIG
                     VIFSSAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            4883..5836
                     /locus_tag="KRM55_000781"
     CDS             4883..5836
                     /locus_tag="KRM55_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBH1593038.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            5874..6836
                     /locus_tag="KRM55_000782"
     CDS             5874..6836
                     /locus_tag="KRM55_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBH1593039.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            6861..7847
                     /locus_tag="KRM55_000783"
     CDS             6861..7847
                     /locus_tag="KRM55_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBH1593040.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            7860..8906
                     /locus_tag="KRM55_000784"
     CDS             7860..8906
                     /locus_tag="KRM55_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBH1593041.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTGKETIVSTNTSKSSE
                     KKELKIENENSRMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            9073..10803
                     /gene="lpdA"
                     /locus_tag="KRM55_000785"
     CDS             9073..10803
                     /gene="lpdA"
                     /locus_tag="KRM55_000785"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH1593042.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            11220..14168
                     /locus_tag="KRM55_000786"
     CDS             11220..14168
                     /locus_tag="KRM55_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1593043.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPVEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            14146..14610
                     /locus_tag="KRM55_000787"
     CDS             14146..14610
                     /locus_tag="KRM55_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1593044.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            14723..15025
                     /locus_tag="KRM55_000788"
     CDS             14723..15025
                     /locus_tag="KRM55_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1593045.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            15087..16451
                     /locus_tag="KRM55_000789"
     CDS             15087..16451
                     /locus_tag="KRM55_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH1593046.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            16486..16959
                     /locus_tag="KRM55_000790"
     CDS             16486..16959
                     /locus_tag="KRM55_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593047.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YVKINDGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            17131..17781
                     /locus_tag="KRM55_000791"
     CDS             17131..17781
                     /locus_tag="KRM55_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH1593048.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREGINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            17955..18887
                     /locus_tag="KRM55_000792"
     CDS             17955..18887
                     /locus_tag="KRM55_000792"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH1593049.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYYDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKNRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            19161..19874
                     /gene="ispD"
                     /locus_tag="KRM55_000793"
     CDS             19161..19874
                     /gene="ispD"
                     /locus_tag="KRM55_000793"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBH1593050.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            19871..20356
                     /locus_tag="KRM55_000794"
     CDS             19871..20356
                     /locus_tag="KRM55_000794"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBH1593051.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    20451..20659
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20723..22438
                     /locus_tag="KRM55_000795"
     CDS             20723..22438
                     /locus_tag="KRM55_000795"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH1593052.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            22560..24005
                     /locus_tag="KRM55_000796"
     CDS             22560..24005
                     /locus_tag="KRM55_000796"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH1593053.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            24443..25924
                     /locus_tag="KRM55_000797"
     CDS             24443..25924
                     /locus_tag="KRM55_000797"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBH1593054.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            26145..26300
                     /locus_tag="KRM55_000798"
     CDS             26145..26300
                     /locus_tag="KRM55_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593055.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            26445..27842
                     /locus_tag="KRM55_000799"
     CDS             26445..27842
                     /locus_tag="KRM55_000799"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBH1593056.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            27827..28240
                     /locus_tag="KRM55_000800"
     CDS             27827..28240
                     /locus_tag="KRM55_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBH1593057.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            28346..29104
                     /locus_tag="KRM55_000801"
     CDS             28346..29104
                     /locus_tag="KRM55_000801"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBH1593058.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLKEVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            29117..29854
                     /gene="rlmB"
                     /locus_tag="KRM55_000802"
     CDS             29117..29854
                     /gene="rlmB"
                     /locus_tag="KRM55_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBH1593059.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            29857..30384
                     /locus_tag="KRM55_000803"
     CDS             29857..30384
                     /locus_tag="KRM55_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBH1593060.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            30449..31096
                     /gene="sigH"
                     /locus_tag="KRM55_000804"
     CDS             30449..31096
                     /gene="sigH"
                     /locus_tag="KRM55_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBH1593061.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            31170..32363
                     /gene="tuf"
                     /locus_tag="KRM55_000805"
     CDS             31170..32363
                     /gene="tuf"
                     /locus_tag="KRM55_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH1593062.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTDKPFLMPVE
                     DVFSITGRGTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLDQAQAGD
                     NIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFDGYRPQF
                     YFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGVV
                     ATIIE"
     gene            32735..33046
                     /gene="rpsJ"
                     /locus_tag="KRM55_000806"
     CDS             32735..33046
                     /gene="rpsJ"
                     /locus_tag="KRM55_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBH1593063.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            33138..33767
                     /gene="rplC"
                     /locus_tag="KRM55_000807"
     CDS             33138..33767
                     /gene="rplC"
                     /locus_tag="KRM55_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBH1593064.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            33797..34420
                     /gene="rplD"
                     /locus_tag="KRM55_000808"
     CDS             33797..34420
                     /gene="rplD"
                     /locus_tag="KRM55_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBH1593065.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            34420..34710
                     /gene="rplW"
                     /locus_tag="KRM55_000809"
     CDS             34420..34710
                     /gene="rplW"
                     /locus_tag="KRM55_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBH1593066.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            34740..35570
                     /gene="rplB"
                     /locus_tag="KRM55_000810"
     CDS             34740..35570
                     /gene="rplB"
                     /locus_tag="KRM55_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBH1593067.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            35605..35886
                     /gene="rpsS"
                     /locus_tag="KRM55_000811"
     CDS             35605..35886
                     /gene="rpsS"
                     /locus_tag="KRM55_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBH1593068.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            35918..36253
                     /gene="rplV"
                     /locus_tag="KRM55_000812"
     CDS             35918..36253
                     /gene="rplV"
                     /locus_tag="KRM55_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBH1593069.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            36276..37091
                     /gene="rpsC"
                     /locus_tag="KRM55_000813"
     CDS             36276..37091
                     /gene="rpsC"
                     /locus_tag="KRM55_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBH1593070.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            37127..37558
                     /gene="rplP"
                     /locus_tag="KRM55_000814"
     CDS             37127..37558
                     /gene="rplP"
                     /locus_tag="KRM55_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBH1593071.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            37560..37763
                     /gene="rpmC"
                     /locus_tag="KRM55_000815"
     CDS             37560..37763
                     /gene="rpmC"
                     /locus_tag="KRM55_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBH1593072.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            37787..38041
                     /gene="rpsQ"
                     /locus_tag="KRM55_000816"
     CDS             37787..38041
                     /gene="rpsQ"
                     /locus_tag="KRM55_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBH1593073.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            38067..38435
                     /gene="rplN"
                     /locus_tag="KRM55_000817"
     CDS             38067..38435
                     /gene="rplN"
                     /locus_tag="KRM55_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBH1593074.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            38459..38764
                     /gene="rplX"
                     /locus_tag="KRM55_000818"
     CDS             38459..38764
                     /gene="rplX"
                     /locus_tag="KRM55_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBH1593075.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            38794..39336
                     /gene="rplE"
                     /locus_tag="KRM55_000819"
     CDS             38794..39336
                     /gene="rplE"
                     /locus_tag="KRM55_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBH1593076.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            39354..39539
                     /locus_tag="KRM55_000820"
     CDS             39354..39539
                     /locus_tag="KRM55_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBH1593077.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            39572..39970
                     /gene="rpsH"
                     /locus_tag="KRM55_000821"
     CDS             39572..39970
                     /gene="rpsH"
                     /locus_tag="KRM55_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBH1593078.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            40001..40543
                     /gene="rplF"
                     /locus_tag="KRM55_000822"
     CDS             40001..40543
                     /gene="rplF"
                     /locus_tag="KRM55_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBH1593079.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            40579..40947
                     /gene="rplR"
                     /locus_tag="KRM55_000823"
     CDS             40579..40947
                     /gene="rplR"
                     /locus_tag="KRM55_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBH1593080.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            40968..41477
                     /gene="rpsE"
                     /locus_tag="KRM55_000824"
     CDS             40968..41477
                     /gene="rpsE"
                     /locus_tag="KRM55_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBH1593081.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            41492..41677
                     /gene="rpmD"
                     /locus_tag="KRM55_000825"
     CDS             41492..41677
                     /gene="rpmD"
                     /locus_tag="KRM55_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBH1593082.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            41710..42153
                     /gene="rplO"
                     /locus_tag="KRM55_000826"
     CDS             41710..42153
                     /gene="rplO"
                     /locus_tag="KRM55_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBH1593083.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            42197..43465
                     /gene="secY"
                     /locus_tag="KRM55_000827"
     CDS             42197..43465
                     /gene="secY"
                     /locus_tag="KRM55_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBH1593084.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            43482..44132
                     /locus_tag="KRM55_000828"
     CDS             43482..44132
                     /locus_tag="KRM55_000828"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBH1593085.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            44133..44879
                     /gene="map"
                     /locus_tag="KRM55_000829"
     CDS             44133..44879
                     /gene="map"
                     /locus_tag="KRM55_000829"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBH1593086.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            44901..45170
                     /locus_tag="KRM55_000830"
     CDS             44901..45170
                     /locus_tag="KRM55_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBH1593087.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            45208..45426
                     /gene="infA"
                     /locus_tag="KRM55_000831"
     CDS             45208..45426
                     /gene="infA"
                     /locus_tag="KRM55_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBH1593088.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            45462..45575
                     /gene="rpmJ"
                     /locus_tag="KRM55_000832"
     CDS             45462..45575
                     /gene="rpmJ"
                     /locus_tag="KRM55_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBH1593089.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            45728..46099
                     /gene="rpsM"
                     /locus_tag="KRM55_000833"
     CDS             45728..46099
                     /gene="rpsM"
                     /locus_tag="KRM55_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBH1593090.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            46135..46533
                     /gene="rpsK"
                     /locus_tag="KRM55_000834"
     CDS             46135..46533
                     /gene="rpsK"
                     /locus_tag="KRM55_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBH1593091.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            46565..47188
                     /gene="rpsD"
                     /locus_tag="KRM55_000835"
     CDS             46565..47188
                     /gene="rpsD"
                     /locus_tag="KRM55_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBH1593092.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            47266..48213
                     /locus_tag="KRM55_000836"
     CDS             47266..48213
                     /locus_tag="KRM55_000836"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBH1593093.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            48234..48575
                     /gene="rplQ"
                     /locus_tag="KRM55_000837"
     CDS             48234..48575
                     /gene="rplQ"
                     /locus_tag="KRM55_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBH1593094.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            48695..49528
                     /locus_tag="KRM55_000838"
     CDS             48695..49528
                     /locus_tag="KRM55_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH1593095.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            49516..50382
                     /locus_tag="KRM55_000839"
     CDS             49516..50382
                     /locus_tag="KRM55_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH1593096.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            50376..51179
                     /locus_tag="KRM55_000840"
     CDS             50376..51179
                     /locus_tag="KRM55_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBH1593097.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            51211..51942
                     /gene="truA"
                     /locus_tag="KRM55_000841"
     CDS             51211..51942
                     /gene="truA"
                     /locus_tag="KRM55_000841"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH1593098.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            52062..52493
                     /gene="rplM"
                     /locus_tag="KRM55_000842"
     CDS             52062..52493
                     /gene="rplM"
                     /locus_tag="KRM55_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBH1593099.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            52522..52914
                     /gene="rpsI"
                     /locus_tag="KRM55_000843"
     CDS             52522..52914
                     /gene="rpsI"
                     /locus_tag="KRM55_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBH1593100.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
BASE COUNT        21469 a         5856 c        10553 g        15209 t
ORIGIN      
        1 tagataataa acatacttaa gaaaacggat aaaatcaaat ataataactg tatattaaaa
       61 taacttaaaa aaattatttt attataagtg caaaatatac ctatttaaat aagataagag
      121 gggaggattt tatgtgtata taaaaggtgt aaatttagga ggttggttag ttttagaaaa
      181 atggatgacc tcaagtttat ttgaaggcac agaagctgaa gatgaatact atttaccaag
      241 acagctttca agagaggcat atgaatctag aattaagact catcgtagtg aatacatcac
      301 agagagagat tttgcaacga ttaaatctat gggatttaat tcagttcgta taccagtacc
      361 atactttatt tttggagatt gtgaaccatt cataggatgt gttaaagaac ttgataaagc
      421 atttgcttgg gcagataagt atgggcttag tatattgata gacttacata cagttccagg
      481 aagccaaaat ggatttgata atggaggaat atcaggtata tgtagctggt cacaaaatcc
      541 agaatatgta gcgtttacat taaatgtatt agaaagactt gcaaaacgtt atgggatgag
      601 gcatgaattg tatggaatcc aaattttaaa tgagcctata acagaaagaa tgtggaacat
      661 aatgaatgtt ccaaatcggt ttaaggctgt agataaggag atggcaaggg ggagtaaacc
      721 taattcatta gagtttttac gtgattttta tataaaagca tataaggtaa tgcgtcctta
      781 tatgagagag gaaaacgtta tagtgtttca tgatgcattt gaattaaaag catggaaaga
      841 ctttatgaga gaggaagaat ttaaaaatgt tgttctagat acacaccaat atttgatgtt
      901 agctgaagca gatggatgtg aacaaagtat tgatagctat ctcaaatata ttagagaaaa
      961 ttatgctaaa gatattttac aaatgcaaaa atattttcct gttatatgtg gggagtggag
     1021 cttatttaat tcatatgctt gtggtataga tacaaatgga ggtcaatcac ctctaaatgg
     1081 gattgaatca aatatagata aattatcaaa agacgataaa agagaattat ataggaagat
     1141 agcaaaagca cagcttgacg catggagaaa tggaagtggt cactactatt ggaattataa
     1201 gttattacta gatacagtta atgaagaagg ttggatagga tgggatagtt gggacctagg
     1261 caaatgtgta gctcaagaat ggtatcctat agaatattaa actaaaattg gaggaaaaga
     1321 tatgattaaa aaccctatac ttccaggttt taatccagat ccttgtattt gtagaaaggg
     1381 agatgattat tatcttgtag tttcatcttt tgaatggttt ccaggtatac ctgtttatca
     1441 ctctaaagac ttaaaaaatt gggagttata tactcatatt ttgacagatg aaacaaaaat
     1501 agatttgaag aagcttcctt catctaaagg aatttgggca ccttgtttga cttattgtga
     1561 agaagaagat ttattttaca tagtttatgg aattatgaac tctatgaatg caagatattt
     1621 tgatgttgat aattatttaa ttacatcaaa agatataaag ggagagtgga gtgaaccagt
     1681 atatctacac tcatcaggtt ttgatgcgtc tatttttcat gatgatgatg gtaaaaagtg
     1741 gattgcatca ttagactggg agactagaga aggatatgaa aaacctggtg ttatatgttt
     1801 agtggaatac tgtacaaaaa agaaagaaat agtaggatat ccaaagagaa tatggtcagg
     1861 gggaactgat agaggttgta ttgaagcacc acatataaca aagcgtggag attactatta
     1921 tataatgtgt gcagaaggtg gaactggata tggtcatagt gtaactatgg gaagggctaa
     1981 aaatatatgg ggaccttatg aaaaagattc aatgaatcca attgtaactt caattccagg
     2041 cgatttttat gaaagacatg accctgacca tctaaagcct aaatactata acccagaatc
     2101 aaaacttcaa aaatctggtc atggaagcta tatagaaaca acatcaggtg aagtatattt
     2161 agttcatcta acatctagac catttgtacc agagttaagg tgtactttag gtagagaaac
     2221 agctattcaa aaaatgagat ggacaaagga taattggctt cgaatggaag atgaaagtaa
     2281 tttggcaaaa gaatacgtat cagaaagtaa actagaagaa catttagttt catctatacc
     2341 aagttttgat gactttgatt caaatgaatt aggtttacag tactatgctc ctaggatttc
     2401 accattatca tttgcagatg ttaagtctag accaggatat gtaaggatta gaggacaaga
     2461 atcaagaaca tcattaaata aagtaagcat attggcaaga aaattaactt cagtatatgc
     2521 aagaataacc actaagatgg agttttaccc agaggtacat cagcatagtg cgggtttgat
     2581 aatgtattat gataatatga attatataaa tttaagaaag tattatagtg aaacattggg
     2641 tcaaagtgca ctatcaataa tacatcttga aaatggagag aagacggaat ttttaaatac
     2701 taggatacca ataaaagata taccaatata tcttcgtctg tatatacaag gtcgtaagtc
     2761 atattttgaa tggagttatg atgaaaaaaa ctaccagaga ataggaaagg tatttgatac
     2821 aactaagttt tcagatgagt actgtaaata tggagaattt acaggtacgt ttatagggtt
     2881 aacttgtgca gatcgtgtaa agcataaaca ctatgctgat tttgattttt ttgaatatat
     2941 agtagatgaa tcaaaagatg tcgattaata aaatcattac taaaattttc agagcaaagg
     3001 taaatcttat gctctgaaat aagaaacatt agaaggcaaa tcttacaaaa aggagtatgg
     3061 tattatgaat acagaagtta atgttaaagc aactactatt agatatgaaa agatttcatt
     3121 ttttgaaaga atttcttatg gttgtgggga tttggggtgc aatatcatat actcagctat
     3181 gtcagcattt ttgctgtttt attatactaa ttatgcagat gttagtgcag cagctgtagg
     3241 tagtattatg cttgtatcta ggatactgga tgggtttagt gacttaacaa tgggaattat
     3301 agtggataga actaaatcca aatacggtaa ggctaggcct tggattttga gaatggcgat
     3361 tccttttgct atagcagcag tattattatt ttctgttcca tcaaatcttg gtatcacttc
     3421 taaattaatt tatattttta ttacatataa cttagtttct actgttattt atacagcaat
     3481 caatgtaccc tatgcaactc taaattcact tataactcaa aaccagtatg aaagaggagt
     3541 attaagtata tttagaatga tattagccac ttgtggtacc ttactaataa atggacttac
     3601 actacctcta gttgaatact ttggaaataa tttatcagca tgggctaaaa cattctttgt
     3661 atttggaata gcatctataa tggtattttt tataacattt actggaacca aggaaagagt
     3721 aaaagcagtt aagcaagata ggaatgaagt aataccattt aaaataggta ttaaatcttt
     3781 atttagaaat aagtactgga tacaaataac attatgttta gtttgcatat ttattgtatt
     3841 tgcgataaat ggtggttcat ccgtatatta tgcaaagttt attttgggag atgaaaaatt
     3901 atttggttct ataaatatgg tttcaaatat atcccaaatt atagctatgt ttatggttgc
     3961 tccttttata aaaaaatttg gaaaaagaaa tgtattaata gtaggttcaa taatattaat
     4021 atcgtcaaat gttatgttta taatagttgg acaagactat ataggagtaa tattttcaag
     4081 tgctataaag ggaataggaa gtgctggaat agcatcaaca atgtttgcta ttgtttcaga
     4141 tactattgaa tatggagaat ggaagactgg atatagaact gaggggctta taaatagtgc
     4201 atctagtttt gggtttaaag tgggaaatgg attaggttca gcaatattag gtgcagtatt
     4261 atcaattggt ggttatgtag gaacatcagc tactcaaagt gatttagcta tagtatcaat
     4321 aaaagtatgt tttatatacc tacctatatt tataacaata ttacaaatta tcataatgtc
     4381 tttttataag cttgataaag aatatagtac tatacttaat gaattaaata ctaaataatg
     4441 aaaaagtttc ttataaagtc ttaagtttaa ttaaggtcta ttgtaaatgt tccctataaa
     4501 aactattata tatttatgat tattgaagaa tttttagaga agcgaataat aaaaatataa
     4561 gaagacttta aatgatgaaa tggttggttt tttagaaatg atttaataag ttattgttat
     4621 ttaaagcatt ataagtggac aattaatttt taatttatgg agatgatatt taacaattag
     4681 aagtaatata taatatgcac taagaagcaa tttttcaact atttatgaag gtggtggtac
     4741 aagaaaagta tcaccttttt tttgttatac aaaaaaacag ttgacttttt atatgaaccc
     4801 cttctataat gttactgaaa ttaagtaaaa tgattgaaca aatgtaaaga taattgaaaa
     4861 gcttgatttt ggaggaaagc aaatgaaaaa aattggagac ttaagattaa tgatgaagtg
     4921 ttgttcactt tattacgaag ataatttgaa tcaacaggaa atagcaaatc aattgggaat
     4981 atcaagacca acaatatcaa gaatattaaa agaagctttt gaacaaggaa tagtaaaaat
     5041 acagatagtt gatgttttga aaaatgatta ccaaaaaata gagagaagtt tggagagaaa
     5101 atataaatta aaagaagtaa tagtagtaga tgataaacag gatgcactaa cacaaaaaca
     5161 agaactagca agagctgtat ctgaatattt aactagagta gtaaaggaaa atgatataat
     5221 aggtgtttca ataggaacaa cactaaaaga aataccaaga tatgtggaaa aaagtaactg
     5281 taaaaatgtt acatttatac ctctattagg agggattgga gacaatgaaa tagatattca
     5341 tgcaaatcaa atagccgtaa gtttagcgag ggcttttgga ggtgatttta aattattaca
     5401 tgctccagct gttatgtctg acttgtctac aaaagagaaa ctttgcaaag acgaaaaaat
     5461 taaagaagtg ctagatttaa tagataaaac aactatagca attgtgggta taggaaatcc
     5521 tatgagttta aactcaacaa taatggcttc tggatacatg aatgaagcag atatagaaga
     5581 tttaaaaaaa tacaactcaa taggtgcaat ttgtttacaa gcctttgata aagaaggaaa
     5641 aacttctata cttgaattta atcaaagagt attaggagtg aaactggaag atttaaaaaa
     5701 gataaaaaga acaataggtg tcgcttcagg agatgaaaaa atagaggcaa taaaggcatc
     5761 attaaaagcg aaatttataa atagtttagc aattaatcac agtttagcac ttaaattatt
     5821 agaagattgt gactaataga aagatagata aaagttaaca ggagggaatg tatatgtcaa
     5881 tatcaaaaga aacattgctt gaaatgtata agagaatgaa tcaggctaga aaatttgaag
     5941 agaaagttag ttggtttttt gcaagaggta tggttcatgg aacaactcac ttatctgtag
     6001 gtcaagaagc gtcaagtgtg gcggctgtaa tggctttaga aaaaggagat ttagtatcat
     6061 taactcatag aggacatagt caatttatag gaatgggaat agacctaaat aaaatgatgg
     6121 ctgaacttat gggtaaagaa actggatttt gtaagggaaa aggaggctca atgcatatag
     6181 cagatattga gtcaggtaac ttaggagcaa atggagttgt aggtggaggt cttacaatag
     6241 ctccaggagc tgcacttaca caacagtata aaaaaacagg caaaatagtt ttatgtagtt
     6301 ttggtgatgg agcatcaaat gaaggtactt ttcatgaagg aataaattta tcttcaatat
     6361 ggaaattgcc aataatattt tactgtgaga ataatttata cggtatgtca acaagcataa
     6421 aacgtcatat gaatatagaa agtattgcca ctagagcagc ttcttatgga atagaaggaa
     6481 tatcaataga tggatataac ccaatagaag tatacgaaac agtacaaaaa gctgctgaga
     6541 agtgtagaag aggagaagga cctgtattaa ttgaaagtag aacttataga tggttaggtc
     6601 attcaaaatc agatgcaaat gtatatagaa caaaagaaga aatagaatca tggaaagcaa
     6661 aagaccctat tgaattttta aaaaattatc ttatagaaaa taatctatct aatgaagatg
     6721 aattagataa gattcaagaa tttgcaaagc aatcaataga agatgcagta gagtttgctc
     6781 aaaatagccc aaatccaaaa atagagtctt tattagagga tgtatatgca gactaagaat
     6841 ggtaaaggag gaaaataaaa atgagtacaa gggaattaac atatgcacaa gcaataaagg
     6901 aagcaatgtc agaagaaatg agaagagatg aaaatgtaat atttatggga gaagatatag
     6961 gaatatatgg aggagcattt ggtgtatcag ttggtatgat agatgaattt ggaccagaaa
     7021 gagtaaggga tactcctata tcagaagcag ctatagcagg agcggcagca ggtgcagcag
     7081 caactggctt aagacctatt atggaagtaa tgtttatgga ctttgtaaca atttctatgg
     7141 atgcaattgt aaatcaagcg gcaaaaatga gatatatgtt tggaggaaaa gcacaagttc
     7201 caatggttgt tagatgccca ggaggttctg gaactggttc agcagagcaa cattcacaaa
     7261 gtttagaagc ttggttttgt catgtaccag gagtaaaagt agttgcacct tctacaccag
     7321 cagatgctaa gggattgttg aaagcagcta taagagataa taatccagtc atatttgttg
     7381 agaataaatt gttatacaga aaaaaaggtt ttgtgccaga agatgattat gtaattgaaa
     7441 ttggaaaggc agatattaaa agagagggta ctgatgttac agtaattact tatggaagaa
     7501 tgttacaaag tgttgaagaa gcagcagaga ctctatcaaa agaaaatata aatgttgaaa
     7561 ttatagattt aagaacttta tatccattag ataaagagac tatagtaaag agtgtatgta
     7621 aaactgggag agttttaatt tgccatgaag cagctaagac tggtgggcta ggtggagaaa
     7681 tatcagccct gataacagaa agtgaatcat ttgattattt agatgctcca gtaaaaagaa
     7741 tttgtggaaa agatgtgcca ataccatata atccagagtt agaaaaagca gttgtcccaa
     7801 gagttgatga aatagaagaa gcaataaaat ctttaattgt tagataagga gggatagata
     7861 tggtggcaaa taaaataaaa gccacaccag cagctagaag tcaggcaaga aaagacaata
     7921 taaaattaga taggctgatt ggaagtggag aaaatggaag gattcattta gtagatgtgt
     7981 taaattattt aaaagataat aaagcaaata ctactccttt agctagaaga atagcagaag
     8041 atttaaatat agatttagaa actattgtag gtactggata taatggaaag ataagaaagt
     8101 gtgatgtgga aaaattaact ggaaaagaaa ctattgtatc aactaataca tctaaatcta
     8161 gtgagaaaaa agagctgaaa attgaaaatg aaaattcaag aatgtttaac acagtagaag
     8221 gaatatttga aaagccaaat ccaatgagag ctactgtagc aaaacgaatg tcagaaagtt
     8281 attttagtgc tcctgtattt acattcaata tagaagtaga tgctacagaa ttgaaggtac
     8341 ttagagcaaa gttaatcgac acagtaaaag aatcaactgg agtaaaatta actatgacag
     8401 atttaatagt aatggcagta tctaaaatac ttccaaatca tcaagcctta aattcagcat
     8461 ggacagatga gggtatattt agatataaag atgtaaatat agctattgca gttggtttag
     8521 atgaaggctt atatgttccg gtagtaaaaa atgcaaacaa aaagtcttta aaagaaatag
     8581 caaaagaaag caaagaactt gcggaaaaag taaagacagg gaaacttatg ccagcagacc
     8641 aagaaggtaa tacatttaca ataagtaatg ttggaatgta tggtataact acatttacac
     8701 ctataataaa tatgccttca agtgcaatct taggggtagg tgctacacaa gataagtttg
     8761 ttccagtaaa tggagaggct aaaataaaac ctataatgaa cttatcatta acatcagacc
     8821 atagagtaat agatggaaca gtagctgcaa aattcttaaa agatttaaaa gaattgttgg
     8881 aaaatccttt atcaatgctt gtataggttt tgatattttg ttactgatat aaatagtttg
     8941 aatagattat attattataa ttgtttcagt aaatttaaag cttttatata ttaagaatta
     9001 tttttaacag taactatatg tgaatatgat ttgcttaatt aaaatataag aaaataaata
     9061 ggaggagagc ctatgtcagt agaagtaata atgccaaaag caggagtagc catggaagaa
     9121 ggtactatag tatcttggct aaagcaagaa ggcgaagaag taaagattgg agaacctata
     9181 ctagaaataa caacagataa agttaatatg gagatagagt cagaaggaga aggtacactt
     9241 gctgtaatca tacataaaga ggaaggtgaa gtattaccag tatttacagt aataggtgta
     9301 atagcagaaa aaggggaaaa tcaagaggaa gtaaaagcta aatatttatc tggaaatgtt
     9361 tcaaaagaag atatagttga agagaatcaa aatatagaat ttaaagaaga aaaaataaac
     9421 aaaaaagagt gtaatcatga ttatgatgta gtggtaatag gaggaggacc tgggggatat
     9481 ttatcagcat taaaagcagc tcttttaggt ggaagagttg ctttagttga agaaaatata
     9541 ctaggaggta cttgcttaaa tagaggttgt atccctacaa agacttatat aaaaacagca
     9601 gaaatattag aagaaattga ccaattatca aagagaggtg taaaagtaac tgtagataaa
     9661 gaacaggaca ttaagaaggc cataaaatat aaaaatagag tagttaaaaa acttacagct
     9721 ggtgttggcg gattattaaa aagtagagat gtagatgtgt ttaatcttaa agctagtgtt
     9781 aaagaagagc ataaagtaat tttatcagat ggaaaagttt tagatacaga aaatataata
     9841 attgctacag gttccaaagt aaggatatta cctataaaag gaatagaatc aaatttaata
     9901 ataactagta cagaagcatt agatttggaa acagtgccag aagaattagt aataattggt
     9961 ggtggagtga ttggttgtga atttgcagag atattcaatt caagaggttc taaagtaact
    10021 atagtagaaa tggaagatag agtaatccca agaatggata aagagttaag cgaatcttta
    10081 aaatattctc ttagtaaaaa aggtataaat gtattaacta aaaagaaagt ttctgaattt
    10141 aaagaagaag gaaataacat attagtgtgc attgaaggtg aagagccaat aaaagcagat
    10201 ttatgtctat atgctatagg aagagaagct aatctttctg gcatagagga cttagatatt
    10261 aaaatagata aaggttcaat agttgtaaat agtaaaatgg aaacaagtat accaagcata
    10321 tatgcagtag gtgatgttac tggaggtgta atgttagctc atgctgcttt taaaatggga
    10381 gaggtagcag cttcaaatgc tctaggtgtg aataaagaag ttgacttagg tgcattacct
    10441 agttgtgttt atacaattcc agaagtagca tcagttggta ttacagaaga ggatgctaga
    10501 aaaaaatata atgtaaaagt tggtaagttt aattttgctg gaaatggaag agctttagct
    10561 tctggtcaag aacaaggata tgtgaaggta gtagcagatg ctaaatatgg agaaatttta
    10621 ggtatacata tgtttggatg tggtgtagca gaacttataa atcatgcagc atcatttaaa
    10681 gcgttagaga tacctactga tgaagcaagt gagttgatat ttggtcatcc atgtacttca
    10741 gaagctttaa tggaagcttt ggcagatgta aatggagaat gtttacactt acctaaaaaa
    10801 taaatctaaa cataaattat taatttaagt ctattattaa tattaattta tatcataaaa
    10861 ttttaaaaca cttacttagc catacccctt attatgcaaa taatttattt gcataataag
    10921 gggtattttt tatggaaaaa tatagaatat agaatccttg tagtttttgt tgtacaaaaa
    10981 agatagtaat ataaaataac attatcattt tagaatgatt tcaattgtaa ttaggaaaag
    11041 tgattttttt gtttttaaaa aaagtattat ttgtaaaata taaaaaaaat ttcttaatat
    11101 ttgaataaaa gaatagctta atttaaatgt tattacttta taaaaaaata ataagtacaa
    11161 aaaaaacaat atatggcata taagttgcta tataaataat aaggagggaa caattataaa
    11221 tgaggcaaag aataaaaaac ttaattgaaa atgaagataa gaaaaatcct ttaacagatg
    11281 aagcgatttc aagtaggtta aatattcgaa gagaagatgt tacctttttg agaaatgagt
    11341 taaaaataga agattcaaga caaagaagaa aagttgtttt aattaaagct ataaaagata
    11401 ttttaaaaga agaaaaaact ataaataaaa atgatataac aagaagatta aacagcattg
    11461 ggtttacagt atcaagattt acagtcatac aatacttaaa agagattcaa gattctggtg
    11521 acctaaaact tgataaagag agtgatgata aaaaagaaga aataatcaat aatagagaaa
    11581 ataaagatat agcatttgat aaactcatag gtagtagtgg tagcttaagt acaattataa
    11641 aactagccaa agcagcaatt ctttatccac ctcatggtct tcatactatt attatggggc
    11701 caactggtgt tggaaagagt gagttagcag agtgtatgta taaatttgca gtagaatcat
    11761 ccagattccc taagaatgca ccatttatag tttttaatgc agcagattat tcagagaatc
    11821 cacagctttt gctatcacag ttatttggac acgttaaagg tgcttttaca ggagctgatg
    11881 agaacaaaga aggattagta tcaaaggcag atggaggaat attgtttata gatgaaatac
    11941 atagattacc tcatgaaggt caagaaatac tatttcaact gattgataaa ggtatggtca
    12001 gaaagttagg agaaacaaga ctaacacata aaatagatgt aatgattatt tcagcaactt
    12061 ctgagccaat agattctcat ttacttaata catttaaaag acgtatacct gtaacaattg
    12121 aaataccaga attagttgca agaccattaa atgagaggtt tgacattata aataatttct
    12181 tcttaataga agctcaaaga atgggagcaa acatacatat aaagtcagat gtattaaaag
    12241 ctcttatgct ttacgattgt ataggtaatg taggtcaact tagaagtgat attcaagtag
    12301 cttgtgctag gggactatta aaccaactta caaacaaact aaaagaagta aatataagca
    12361 tatcagatgt acctggatat gtaaaacaag gtcttataaa aatcagaaat tgtagaggga
    12421 aaatagaaaa ttatgtagat ggggatttaa ttatagactc aaatcttcaa ggtgagatag
    12481 aaaagaaaaa tgaagatata tatacttttc cagatgaaat atacaaactt actgaaagaa
    12541 gacatattga tttattggaa caaggtttag attttgatgt tataaataga atcattggag
    12601 gagaattaga aagttgcatt caaaaataca taaaacaagt taaaaaagtt tctattagta
    12661 acaatcttcc agatataagt ccaattgttg gaaaatatat cgtagagcta acttatgaag
    12721 taatcaaaat agcatcacaa tacctcagtt cactagaacc gaatctacat ttatgtttag
    12781 cagttcacct aaaagcagct tttgagagat taaaagaagg aaaagtaata tcaaatgctc
    12841 atttgaaaga aataatagga aattatccag tagaatattc tgtagcagaa aaggtagctc
    12901 aatatttaaa ggaaagatat aacataaact taccaaaaga agaaataggt ataatagcaa
    12961 tatattttaa aatgagtagt agaagagata tgtctgaaca aaaaaagata ggcgtacttc
    13021 ttatggctca cggaagagta gcatcttctg tatgtgaggt tacaaataaa ctattaggaa
    13081 ttaatcacgc aaggtattta gatatgccat ttgagaagaa gccggaagaa atgattgaag
    13141 aagctactac aataataaaa gatattgatg aaggtagagg tgtgattata ttagtagata
    13201 tgggttcact ttcatatttt ggagatatta tttctggaaa gactggaatt aatataagga
    13261 caatatctag atttgataca ttgctttcta tagaggttat acgaagagca gttttaccag
    13321 atttaacaat agacgagata gttgatgaag ttaaaggtat agagccacaa gtaaaagaaa
    13381 aggttagtaa atgtaacaat acaaaagtag attttagaaa acctataatt ttaacattat
    13441 gtattactgg attaggggga gcttgtaaga taaaaaaaat cttagaggaa aatattaaaa
    13501 gtataactga aaaggttgat atagaaccta taggtatgat tgaatatcca agtcttgatt
    13561 tagagataaa acaaataagc aatgataaaa atgtaatcgc catagttgga acaattgacc
    13621 ctcagatagc aaatatccct ttttttagtc tagtagacat aaatgataaa gcaaagttaa
    13681 atcaaataaa taacctaatt gatacaaatc aaattggtga aacaaataaa aaatatgaat
    13741 tatcagattt aatacataaa gaagatatat ttgtggattt acaggttaaa tcaaaagaag
    13801 aagttctaaa atatatgagt aaaaaactta gagagaaagg ttatgtgaca aaaaatttct
    13861 ataaaaaagt agtggaaaga gataacttat ttccaactga attatcagat gaaatagcaa
    13921 tacctcacac agatggaata gatgtaatta ggccagctat aagtatagcc atcttaaaga
    13981 agcctattgt gtggagtaaa agtaaagtaa aaataatact tttattagct gtagaccaaa
    14041 agtgttttaa tccattaagc actctactct catttataga aacagatgaa tttaagaaga
    14101 taaaaaacat taaagataga gattttatta gggagatgat attagatgga gtcaatgaaa
    14161 ataattagta gcaatttaat ttttaaaaat attgaagtgt ctaacaatga agatgcatta
    14221 aagtttttgg gacaacgttt gtttgacgaa cagtatgtaa aagaaagcta catacaagct
    14281 gttgtagcaa gagaaaaaaa gtatgctaca gggttaccaa cagaaatata cggagtggca
    14341 ataccacata cagatatagt acatgtaaat gagccaggaa tagcaattgg aatactgaat
    14401 aaacctgtaa aatttataat gatgggtaca gacgatactg aaattgatgt aaaagttgta
    14461 tttatgttag cagtgaaaga gccacaagaa caattgcaac tattagaaaa acttatgact
    14521 atatttcaag ataagaatat actaaataat attgttgact taagtgaaga aagtgtgagt
    14581 gatttattaa actctaaatt gaaaaattaa acatgtaaag tatattaaaa atgtaaaatt
    14641 aaacatgcaa agtatgttaa aaaatataaa aagattatta aagatttcta actatagata
    14701 tctttaaaat aaaataattt caatgggggt gactaatgtg gctaaaaaga tattagttgc
    14761 atgtggaaca ggagtatgta cttcaacaat tgctataaac aaattaaaga aagcacttca
    14821 agacattggt aaattggata tggttaatat tacacaatgt aaagtagtag aagttgcatc
    14881 aaaagcacct gattatgatt taataatttg tactacacaa gtatctagta gtataaaaac
    14941 accagtgata aatggcttac cttttttaac tggtgtcgga atggataaat taatcaatga
    15001 tgtattagaa gagttagaat tataattaaa aaaattaagg aacatggtct ctaaaatcat
    15061 aagttttaga gacttaaaat taaataatgg agggtcttta tatggagata ttaaatttca
    15121 ttgttggtct aggtgcacaa gtaatgatgc caataataat atgtattttt ggtttgatat
    15181 taggtacaaa actaggaaaa tctttaagag ctggtttaac tgtgggagtt gggtttatag
    15241 gtcttaacac tattatagct ttgctaacag ataatttagg tccagctaca caacaaatgg
    15301 ttaagaattt agggctaagt ttatcaataa tagatgtagg atggccagca gcatcagcta
    15361 tagcttttgc atcaacagta ggggctttaa ttattccaat aggtcttgtg gtaaatatag
    15421 ttatgctaat tactaatact actcaaactg ttgatgtaga catatgggat tactggcatt
    15481 ttgcttttac aggagcttta gtggcagggg ctactcaaag tgtaatgtgg ggagtatttg
    15541 cagcagtagc aaatatggta attgtattgg taatggcaga tttaactgct ccaggtatag
    15601 aggaatattt aggtatgcca ggtatatctc ttcctcatgg atttacacag gcatttgttc
    15661 caattgctat agtagtaaat aaattattag acctaatacc aggcataaat aagattgaga
    15721 taaatgctga tacattgcag aaaaaatttg gattatttgg agaaccttta ataatggggt
    15781 ctgtaatagg tgtaataatt ggtattgctg cgaaatatga tataaaagga atattacaat
    15841 taggtgtaac tatgggagct gtattaatat taattccaaa gatggcagca ttattaatgg
    15901 aaggattatt accagtatca gaagctgcac aggaatttat tgagaagaga tttaaaaaca
    15961 gaggcaagat ttatataggc ttagattcag cagtaggaat aggtcatcct gttacattat
    16021 cagttgcact agtgttggtt cctttgacta tacttatagc agctatattg ccaggaaata
    16081 aagttttacc atttgcagat ttagcagtaa ttccatttgc acttgtatta atcgtaccaa
    16141 ttacaaaggg aaatgtgttt agaacattaa taataggaat aattataatt acttctggat
    16201 tattaatcgc aactaactta gctccattat ttacccaaat ggctttaaat gctagtttta
    16261 aaatgcctga aggagcaact atgatttcaa gtatttgtga tggtgcgaat ccattaagtt
    16321 gggtatttgt aaaagttatg aactataaag ttattggagg agtagttttt ggagttatag
    16381 ctttaggaat ggctatttac aataggaata gaataataaa tgaaaataaa aagctatcta
    16441 tagaagaata aggctaaaac aattttatta aggagtgtat aggttatgaa aaaatataaa
    16501 tatgattcta aaagatactt actcagtgtt acaataccag gattttttat gattttaata
    16561 ttgatttatg cactgtttaa taactataca aattttaatt tgaatatata tagtttgtta
    16621 ataattgtct gtacttatgg tatattcaat acttttatat catcaagtaa tcctaaaaaa
    16681 attattattg atagcaaatg tatacatttt acctcattta tgactacaca taagtatgaa
    16741 attaaagata tagaaaagat aagaataaga gaattttata ataaaaaaat ttatgtaaaa
    16801 attaatgatg gaaacctttt taaaggtagg tattggataa gaacaaatat gtttaataat
    16861 agtatagcat tatatagcta tttcattgag ttggaagagt gcttatatcc agattcacta
    16921 aaatttagaa ataaaaaatt tgagaataag aacatataaa aataaaaaat tgaattgaag
    16981 cctagcttaa tcttttttga taagatataa gtttgaactt tatactaaat ttttagaatt
    17041 ttcaatcaag acaataacat aatagctaag caattagaac acaattaaga tgtataaggc
    17101 atgtatatga tgaatgggag gatttaatta atgttattag agaaattaag aaaagaagta
    17161 ttacaagcat ctttagacct tttaaactat aatttagtga cattaacagg aggaaatgta
    17221 agtgggagag atgaacaaac tggctatata gcaatcaccc caagtggaat ggattataga
    17281 aatcttacac caagtgatat tgttatagta gatgtagatg gaaatattat agatggaaaa
    17341 tggaaagcat cagtggattt atcagaccac ttgtatatat ataagcatag agaaggcata
    17401 aatagtataa ttcatacaca ttctacatac tcaagttgtt ttgctatttt aaatgaacct
    17461 atagaatgtg caagtacaac tcttgcaaat gaagtagggg gttcagtacc agttgcaaaa
    17521 ttttcaccac caacatctaa aaagatggga aaatgtgtta ttgaagcaat tggtgacaaa
    17581 agagcatgtc ttttagcaaa tcatggcgta attgcagttg gtccatctgt aggacatgct
    17641 cttacagccg ctgtaatgtt agaagattca gcaaaagtat attacttagc aaaatcaatt
    17701 ggcacaccag tgctactgcc tgatgaagaa attcaaagag cgagagatgt attttttaat
    17761 gtctatggtc aggataaata aattagataa aattttaaaa gtaatatgaa aatatagata
    17821 ttcaatgata ttaaggagat ttataatgat ataataagtt taatagttaa gaagtaaaat
    17881 atgaaatgta atagtatata aattcattta agactaaaaa gaataagata aaataaaaag
    17941 gagtctgtat ttctatgtat tacttattaa acaaaagcac aaatccttac tttaatttgg
    18001 cattagaaga atatctattt ttaaatgata aatataatga tgatattata atcatatgga
    18061 gaaatgaaga atccattttt ataggtaaaa atcaaaatcc atatcaggaa gtatattatg
    18121 atgttattga aaagggagaa attcctattt taagaagaat atctggagga ggaactgttt
    18181 atcatgactt aggtaatatc aatatgtcat tcatacaaaa aaataggcaa cttcatgaga
    18241 tagatttttt ggagcacact aagtttatgc aaaagatgct ttcaacctta ggactagatg
    18301 tatctataac tgaaagaaaa gatttatttt taaatgggaa aaaaatttca ggttctgcac
    18361 agtctataaa aagaaaaaat tctctttatc atggaactct tctttacgat tcagatttaa
    18421 ataaattaac taaatattta aattcaaata aagcaactga atcaaatgca actaaatctg
    18481 tttcaagtaa agttacaaat attaagtttt tactcgaaaa agatataaat tactttttag
    18541 attattgtgt tgaatattta aaatctaata taaagaatat aaaagaactt gaattggatg
    18601 aagaagatat taaaagtgta tacaatatag gagaagataa atataaaaag atagagtgga
    18661 catatggtaa aacgccgaaa tttcaagtag tgctaccatt taataatgaa agtaaaataa
    18721 atatacatgt taacagatgg aaagtatcaa aattttttat ttcttatgat gataatgtaa
    18781 ttaatatgga caagttgtta gatttgaatt tctttaaaga agaaataaaa gagagtattt
    18841 tagaaaatta tccacattac atagatttaa tcaatttaat attttaatat aaaacctcta
    18901 atttgataaa attgtcttat atcaaactag aggtttttaa tattcttgca tattaacaac
    18961 cattacaaaa ttgtaaaatt aaaaacaaca ctattgaaaa atcaatatat attgtaataa
    19021 atatatgtgt ttttcattag caaatagaca ttaactattt atacaactga aaatttaata
    19081 tataattaat cagatggtta aaataaaaat attaaaagtt ttaataaatg atggttaaaa
    19141 ataaaatacg aggtgatacc atgtatagtg ttataattgt tgcagcggga agcggaagga
    19201 gaatgaactt agatataaac aaacagttca taaaattaag agaaaaagaa attattgctc
    19261 atacaattca agttttttat gaaaatataa atatagatga aatagtggta tgtataaaaa
    19321 aagaagaaga agattttttt aaagaaaata taataaataa gtataacttt aaaaatataa
    19381 aaatagcata tggcggaaaa gaaagacagg actcaatata taatggttta aaaaaattag
    19441 atgaaaattg tgatatagta cttatccatg atggagcaag accatttgtc gaccatagaa
    19501 taatcaatga atctataaag gtagctaaag aaaaaaaggc tgtggttgta ggtgttccag
    19561 taagtgatac tataaagata gtgtcagatg gaacagtaca agaaactcca gaaagaaatt
    19621 tgctgtgggc agcacaaacc cctcaaacct ttgaatataa tctcataata gatgcttatg
    19681 aacaagcata taagaacaat tattatggta ctgatgattc aatgttggta gaaaatatag
    19741 gtcaaagtgt cactatggta atgggttctt atgaaaacat aaaaataact agtccagaag
    19801 atttaaatat agcagaacaa atattaaata tggaaaaaag agatgaagtt aacagtagaa
    19861 ggagaattat atgagaatag gattaggata tgatgtacac aaattaacag aggatagaaa
    19921 acttataatc ggtggtgtag agataccaca cgataaaggt ttgttgggtc attctgatgc
    19981 tgatgtattg atacatgcaa taatggattc tattttaggt gctctagcat taggagatat
    20041 agggaagcat ttcccagata cagatgaaga atataaggga gcagatagta tgaaattatt
    20101 agaacatgtg tataatctaa taacaagtaa aggatataaa attggtaata tagacagtac
    20161 tataattgct caaagcccta agatggctcc atatattgag agtatgagaa gtaatatatc
    20221 aaaagtttta aacacagaca ttgataatat aaacataaag gcaacaacag aagaaggtct
    20281 tggttttaca ggagcaaaac agggaatagc ttcacaaagt atttgtttat tattgttgac
    20341 aagtcagaat aattaatata ttattagtaa taagtttaat ggatatcaag taataggcct
    20401 atatagaata tctataatgt atgaatttaa gtgaaattaa tataaatata aaattagcta
    20461 tgataaagaa atagtaaaat gatgaaatct tcacagagag aaaacggtgg tgagagtttt
    20521 caagaggaag tctttgaacc tgtcttttag cttaaaggta taaaaatctt tacggtagga
    20581 accgttatat tcccaaaaga gagctattca tatagctaac tagagtggta ccgcggaaat
    20641 taaacctttc gtctctatac ttgtatagag atgagaggtt ttttatattt tcaggaagtt
    20701 aatattcagg aggaatctat taatgaaaat gtcaaaaatg tttatgccga cattaaaaga
    20761 aatcccagca gatgctgaga ttacaagcca tcaattaatg gttaggtcag gcatgataaa
    20821 aaaaatgact tcaggtgttt ataaccaatt accaatgggg ttaagagtgt tcaaaaaaat
    20881 tgaacaaata attagagaag aattaaataa aaaagattgt caagaaatac tttgtgcagc
    20941 cttacttcct tctgaattat ggaaagagtc tggaaggtgg actgctatgg gtgaagaaat
    21001 gtttagacta aaagacagaa cagaaagaga gtactgtctt gggccaacac atgaagaagc
    21061 attcactgat ataataagac aagaaattac ttcatataaa caattgccac taaacttgta
    21121 ccaaatacaa gtaaaatata gagacgagag aagaccaaga tttggtgtta tgagaactaa
    21181 gacttttaca atgaaggatg cctatagttt tgatgtagat gataaaggtt tagataagtc
    21241 atatcaagat atgtttgatg catatgtaag tatatttgat agatgtggat tggagaatag
    21301 ccctgtacag gcagattcag gagctatagg aggttctaca tcagccgaat ttatggttaa
    21361 gtcagaagtt ggtgaagatg aagttgtatt ttgtagtgga tgtgattatg cagccaatgt
    21421 agaaagagca gaatcttgta atctagcatc acaaaaagaa gaaatgaaag aattagaaga
    21481 ggttcataca ccaggagcag ctacaataaa agagttagaa gaatttttaa aaacttctcc
    21541 agataagttt gctaaaactt tagtatatga ggcagatgga aaaacagttg tagtcgttgt
    21601 aagaggagat agagaagtta atgaaatcaa agtatctaat gccataggtt ctgttataga
    21661 atttgctctt gctacagatg atgtagtgag aaaagtaact aatgcagaag taggatttgc
    21721 aggtccaata ggtataaatg ctgactatgt atttatagat aaagaaattg ttgaacaaag
    21781 aaacatagtt gttggggcta ataaaactga gtaccatata aaaaatgcta actatggaag
    21841 agattttgaa ggaatagttg gagattttag aaatgttcaa gaaggcgaca agtgtatagt
    21901 atgtggtaag ccacttgaaa tagctagagg tgttgaagta ggacatatat ttaaactagg
    21961 aactaagtac tcagaatcta tgaatgcaaa cttcatagac aaagatggaa aatcaaagcc
    22021 tatagtaatg ggatgttatg gaataggtgt tgaaagaaca gcagcagcta taattgaaca
    22081 acataatgat gagaaaggta taatatggcc tttgtcagta gctccatacc atgttgtgat
    22141 agttccagca aatatgaaaa atgaagaaca aatatcaata gctgaaaata tatataatga
    22201 tttgcaagct atgggtgtag aagttttatt agatgacaga gatgaaagaa taggtgtcaa
    22261 attcaatgat tcagaattaa taggaatacc tatgaggatt acagtaggta aaaatattaa
    22321 tgaaggtaaa gtagaattta aacttagaca taaagaagat aaagagataa ttgacataga
    22381 agaaataaat gaaaaagtaa aggcagagtt tatcaggaat aatgttaggt taggataata
    22441 acttaaataa gatattgtat agataatcaa agttgtactt tatagacacc attttatcta
    22501 tatataagga tataaaatgg tgttttttta taaaacaaat aaatgaggag gtaattgaaa
    22561 tggcaaaaaa tgaaaaacaa tttgttgaag aaataacaaa gatggaagat gattttccac
    22621 aatggtacac agatgtaata actaagactg acttagttga ttatgcacca gtaaaaggtt
    22681 ttatggttgt aaagccatat ggatatgcat tatgggaaaa gatgcaagaa tttatggata
    22741 aaaaatttaa agaaactgga cataaaaact gttattttcc attattaata ccagagagtt
    22801 tattaaacaa agaagcagaa cacgttgaag gttttgctcc agaagttgca tgggtaacac
    22861 atggaggaaa taaaaaatta gaagaaagat tatgtgtaag acctacttca gagactataa
    22921 tatgtacaat gtatgcgaaa tggttaaaat catatagaga attaccatat ctttataatc
    22981 aatggtgctc agttgttaga tgggaaaaat caactagacc tttcttaaga acatctgagt
    23041 ttttatggca agaaggtcat acattacatg aaacagcaga agaagcacaa gaagaaacaa
    23101 tacaacaatt agaagtatat aaagcgctat gtgaagaatt acttgcaatg ccagttgtag
    23161 ctggtcaaaa aagtgaaagt gagaaatttg caggtggtga aagaacatat actatagaag
    23221 ctatgatgca tgatggtaaa gcattacaat caggtacaag tcacttccta ggtcaacact
    23281 ttactaaggc ttttgatatt acttttgcag atagggaagg aaatttagct aatccatacc
    23341 atacatcttg gggagcatct acaagactta taggtggact tataatgact catagtgata
    23401 acagaggttt agtattacca ccaagagtag ctccaattca agttgttata gttcctatag
    23461 ctgctaaaaa aggaaatgta atggagactg ttgataaaat atatgctgat ttaaaagcta
    23521 agggagtagc tgtagaagtt gatgatagag ataactatac aactggatgg aaatttaatg
    23581 agtgggaaat gaaaggtgtt ccagtaagag ttgaaattgg accaaaagat atagaaaata
    23641 atcaagctat ggtatttaga agagatactt tagaaaagga ttctatgcct ttagaaggat
    23701 tagctgatgc tatatgtgat ttatttgatg ttatacacaa tgatatgttt gaaaaagcaa
    23761 gaaaacatag agaagacaat acatctatag ttgaaaatat ggatgagttt agaaaagctt
    23821 tagaagaaaa gccaggattc ataaagacta tgtggtgtgg agatgcagaa tgtgaagcta
    23881 agattaagga agaaacagga gcaactataa gatgcttacc ttttgaacaa gaaaacttag
    23941 gtcacaagtg tgtgtactgt ggaaaagaag cagatagtat ggtagtaatg gcaaaagctt
    24001 actaaaatac atttaaataa aaactggggt agaaagtatt taatacttta tcccagtttt
    24061 ttgtttttta tgagtaataa aatgtatttg taactatgtc ataagataag tcatagatac
    24121 ttatattaaa aagaatataa tagagaacta tttttaataa ttacatatta atgaaagcaa
    24181 aatattttgt tatatagatt ttcaataaag caaacaataa atataaatga atattaataa
    24241 ggagtgcttt taatttttag aaaataaatg acttaaaaga aagatttatg aaattaaaac
    24301 taggattttc tgatataata aacatgtgta tttttaaata aaaaggatat tattattaga
    24361 tttgattaaa aataaacttg caaaacaatg tactagttta atattatagt tatattgaat
    24421 aaaatatcag gaggaagtaa aaatgaatgt aagagtaagg tttgcaccaa gtccaacagg
    24481 atttgtacat ataggtagtt tgagaactgc tttatataac tatttatttg caaaaaaaat
    24541 gggcggagaa tatatattaa gagtggaaga tacagaccaa agtagattag tagaaggtgc
    24601 tatagagaat atgcttaatg ctatgaaatg ggctggggtc aaccatagtg aaggtgttat
    24661 attagatgat agtggaaaag tagtacaaaa aggagaatat ggtccatata ttcaatctca
    24721 aagattagat atataccaag aatatataaa gcaactttta gatagtggaa aagcttatta
    24781 ctgtttctgt acaaaagaaa gactggatga agtaagagat gctcaaagag cagcaggaga
    24841 aacagctaaa tatgatggtc attgtaagaa tctttctaaa gaagaagtag aagcgaatat
    24901 aaaagcagga ataccatatg ttataagatt aagattgcca gagaatcata caattaagtt
    24961 tacagactta gttagaggag atatggaatt taatactaat gacttagatg accaagtatt
    25021 aatgaaaaca gatggatttc caacttatca ttttgcagta gttgttgatg actatttgat
    25081 gaaaattaca catgttataa gaggagaaga atgggtatca tctactccaa aacatgttta
    25141 tttatatgaa gcttttggat gggaagcacc tgtatttgtg catttaccaa atatacttaa
    25201 taaagaaaag aaaaaattaa gtaaaagaca aggtgatgta gctgttgaag actttaagaa
    25261 aaaaggatat ttaccagagg gattagtaaa ctatgtagca ttagttggtt ggtctcctga
    25321 agataatcaa gaattgttta caatggagga attagaaaaa gccttctctg tagaaagagt
    25381 ctctaaaagt ggtggagtat ttgatactga aaaattaaat tgggttaatc agcattatat
    25441 aaaagatggt gatgatgctt atctaacaga cttagcaata ccatttttaa tagaagatgg
    25501 atttataaca gaagaagaag ctactaataa atatgatttc ttaaagagta tgatatcagt
    25561 acttaaagag aaattacaat atgtaaaaga agttactgaa catgcaagta tattttttgg
    25621 agataaaata gaggtagaaa ctgaagaggg aagagagttc ttaagattag aacatatacc
    25681 tactttaata gatgctttga gagaaaaaat agaaaaaaca gaggtattaa atgctgagtt
    25741 tgttcaagct atgcttaaag aaatacaaaa agagtacaaa ataaaaggga aaaatttatt
    25801 tatgggctca agaataattt tgacagggca aatgcatggt ccagatttac caaaagtaat
    25861 ggaagtttta ggaaaagaaa cttgcttaaa tagaatagct tatgtaaaaa ataatatatt
    25921 atagtcataa aagtccgcta atttagaagc ggactttttt tgtgttagta tttggtgaaa
    25981 atatctgctt aagaaaatga aggtatttaa ggtaataaat ttaatatata aaaagcaaag
    26041 caaaaatata aataaaatat gaataataaa ctaataaaat attaagcata gaagaaggga
    26101 atctattatt ttagtttgat ttaattatta agggggtaat tactatgtat agtaatattg
    26161 atgatgttaa aaaggaatta aaggagctat gcttagaata tgttacaatt ttagaaaaat
    26221 taaaagatga aaaaatgatt acagaagaaa cttttgaaaa gtgctcttct caaaaaaaaa
    26281 tatttttaga agaacaatag aggatggtaa tagtattatt attatgtagt ttgaaagata
    26341 gtacgaaaaa tgatagtaat actattattt attgcaattt tcaactataa tataatatat
    26401 aatgttaaga agataattta taaaaataca gtgaggtgat gagtgtgaaa gtttataata
    26461 cattgactag aacaaaagaa gaatttgttc cattagaaga aggaaaggta aaaatgtatg
    26521 tgtgtggtcc aacagtttat aactatatac acataggtaa tgcaagacca tttataatat
    26581 ttgatactct aagaaggtat ttagagtata gaggatatga tgtaacttat gtacaaaact
    26641 ttacagatgt tgatgataag attataaata gaagtcatga ggagggaata tctcctgaag
    26701 aagttgcggc taagtatata aaagaatatt ttgtagactg tgatgggcta ggaataaaaa
    26761 gagctactgt tcatcctcag gttacagata atatacaaca gattatagag tttataaaag
    26821 agttggaaga taagggatat gcatatgcag taaatggtga tgtatatttt gatacaaata
    26881 agtttgaagg ttatggaaaa ctttcaggtc aaaaacaaga agatttagag gcaggggcta
    26941 gaattgaggt taatgaccaa aaaagacatc ctatggactt tgttctttgg aaggcaaaaa
    27001 aagaaggtga gccaggatgg gatagccctt ggggagaagg tagaccagga tggcatatag
    27061 aatgttctgt tatgtctaag agatatttag gtgaaacaat tgatatacat gcaggtgggc
    27121 aagatttaac attcccacat catgaaaatg aaatagctca aagtgaagct agaagtggaa
    27181 aaacattctc aaaatactgg atgcataatg gatatataaa tataaatgat gaaaagatga
    27241 gtaaatcaaa aggtaatttc tttacagtaa gagatatatc aaaattatat gatttagaga
    27301 tagtaagatt tttcatgtta tcagcacatt atagaaatcc agtaaacttt agtgatgaga
    27361 tgttaaatca agctaaagca ggtcttgaaa gactatataa tactaaagaa aaattagaat
    27421 ttacgctaag taatttagtg gaatctcctt taacagaaaa agaagtagag cttgttaaag
    27481 aattagatga ctttagacaa aaattcatag atgctatgga tgatgatgtt aatacagcag
    27541 acgcagtaag tgtaatattt gaattagcta agttaataaa ttctaatgta gatgaaaatt
    27601 cttctttgga gtttgctaaa aaatgcttag atgaatttaa tgaacttaca ggagtattaa
    27661 atattgtaaa taagaaaaag gatactgtat tagataaaga cattgaagaa ttgatacaaa
    27721 aaagaactga tgcaaagaaa aataaagagt ttcaattagc tgatgatatt agacaacaat
    27781 tactagatat gggaattgta ttagaagaca caagacaagg tgttaagtgg aaaaggatat
    27841 aaaaatggaa aaaactgaat tagttactat gtcaccatta gttttagcat acttaggtga
    27901 tacagtgtat gagacatata taagagaata tttaattaga cagaatacac aaagaaaagt
    27961 taatgatttg cataaactag ctataaagta tgtaaaagct aaagctcagg caactataat
    28021 tcatgaaatt gaaattgagt taactgaaga agagagtaaa atttataaaa ggggaagaaa
    28081 tcaaaagtca aatacttctc ctaagaatgc agatattata gactacaaac atgcaactgg
    28141 gtttgaggca ttagtgggat atttgtattt aaataatgaa atagagagac ttcaatatat
    28201 tatcaataaa ggaatcaaaa ttattgaaag agatatgtaa atattaaaga gtgttgtctt
    28261 aataataagt aataaggcaa cacttttttt ataactaatg tataataaat atatagaaat
    28321 tagtaatgag aaaggataaa aagttatgaa agtaaaatta atatcacata cacctgaacc
    28381 agaaaaagta atagctatgg cagctaagct atgttattca ccagttggga cagacgaaat
    28441 agaaaaagac ttaacagatg aaagtataga gaaattttta aatatgttat taagtatagg
    28501 tcatgggtca atattagaac atgcttcatt tacattttca atagaaggta tttcaagggc
    28561 ttgttcacat caaattgtta gacatcgtat agctagtttt tcacaacaaa gtcaaagata
    28621 tgttaaatta gaacaatttg agtacataat tcctccagaa atagaaaaaa tagaaaaagc
    28681 aaaagagtta tttatagact ccatgaaaaa agaccaagag aattatgata agttagttga
    28741 aatattgttt gaaaatcatt ataatgacct aataaaaaac ggtaaaaatg agaaaacagc
    28801 taaaagacaa gctgaaaaga aagcaataga agatgctaga tacgtatttc caaatgcatg
    28861 tgaaacaaaa atggtattta ctataaatgc tagaagtttg tttaatttct ttgaacatag
    28921 atgctgtgaa agagcacagt gggaaataag aaatttggct gtggagatgt taaaagaggt
    28981 taaaaaggtt gctcctatat tatttaaaaa aactggtcca agttgtgtaa atggaagttg
    29041 tccagaagga actatgactt gtggagatat agttcaagtt agagaaaaat ttaaggcctt
    29101 gtaggaggtg aataatttgg cgagtataga aggaagaaat ccggtaatag aagcaataaa
    29161 aagcgacaga gaaatagata aaatattaat tgcaaattca gctaaagaag gttcaattaa
    29221 gaaaataata ggaatggcta aagataagaa tataattatt cagtatgttg ataaacataa
    29281 gctagatgaa gtaagtacaa gtcattcaca tcaaggtgta atagcttatg caagtgagta
    29341 taagtattat gaattagatg agctaataga tttagcaaag aataaagatg aagacccatt
    29401 tttcattata ttagatgaga taacagaccc acataatttg ggttcaataa taaggacagc
    29461 agatgcagta ggagcacatg gagttatcat tccaaaaaga aggtctgtac acataactcc
    29521 tgtagttgcc aaagcatctg ctggagcagt agaatatatg ccagtttgca aggtaaccaa
    29581 tatagttaat acaataaaaa gactcaaaga agaagggctg tggattgctg cagctgatat
    29641 ggatggagaa actttttata aacaaaatct tactggtcct cttggtgtag taattggaag
    29701 tgaaggtttt ggaatatcta gattggttaa acaaaactgt gactttatag taaaaatgcc
    29761 aatgataggt aatgttacat ctttaaatgc atctgtagca ggtggaatac ttttatatga
    29821 gatattcaga caaagactgg ataaaagtaa ataggcatga aaaaaaatat aaatcattac
    29881 ttaataatag atggctacaa tattataaat gcgtgggaca atttgaaaga actggctaaa
    29941 gaggacttag aagattctcg agaaaagctt attgatgaca ttatagaatt ttctgagttt
    30001 atgggttata agactataat agtttttgat gcttataatg ttaaaaattc tcgagaaaaa
    30061 gttgaaaaaa gaaaacacat aacaatagtt tatacaagag aacaccaaac agcagatagt
    30121 tatatagaga aatttataac ttctttatca aagtatgatg atgtaaaagt agccactaat
    30181 gactatgcag aacagcaaat gattttagga aaaggtgcta ctagaatgtc tgcaagagaa
    30241 ttaaagttag agttagatcg ttccaagaat aaaatgaagg aaaaaaatat cggtttgagg
    30301 aaaaaaattc agcgaaattg gttggaggaa aggttagata aagaaacatt gtcgaaactt
    30361 gagaacattc gtagaaagcg ttgaaattac taggttcttt agactataat atacctataa
    30421 atttgtttta tatatggggg agatttacat gttggtagca aaagaaaaaa gttatgagtt
    30481 agtggacaat tgtcagcagg atgagtataa cattgtatta agagcaagtg aaggggataa
    30541 aatagcacta gagtacatta ttactaaata cagaaatttt gtaaaggcaa aagcaaagtc
    30601 atatttttta attggagcag ataaagaaga tataatacaa gaaggaatga taggccttta
    30661 taaggcagtt agagattttg atggaagtaa gaccaattca tttaaatgtt ttgcggagat
    30721 atgtataaca agacaaataa taactgctat aaaaactgca acaagacaaa aacatatacc
    30781 tttaaattca tatgtttctt tgaataaacc aatatatgat gaagagtcag acagaacact
    30841 tttagatatt atagctacaa gtatagtaac agatccagaa gagcttataa ttagtaaaga
    30901 agagttaaaa aatatagaat caaaaatgaa cgaattgtta agtgacttgg aattagaagt
    30961 actagaatta tatttaaatg gaaagtcata ccagtttata gcggacaagc ttaaaagaga
    31021 tgtaaagtca atagataacg ctttacaaag ggttaagaga aaattagaaa aacatcttga
    31081 aaacagaaat gattaatagt aaaatactta ccataagctt attgtgagca aaattaattt
    31141 atatcgaaag ataagggagg aaattcaaaa tggctaaagc taaatacgaa agaacaaaac
    31201 ctcatgttaa tatagggaca ataggacacg tagaccacgg taaaactaca ttaacagcag
    31261 caataacaaa aacattatat gacagatatc aattaggaga agcagtagat ttcgcaaaca
    31321 tagataaagc tccagaagaa agagaaagag gaatcacaat atcaacagca cacgttgagt
    31381 atgaaacacc aaatagacac tatgcacacg ttgactgccc aggacatgct gactacgtta
    31441 agaacatgat aacaggagca gcacaaatgg acggagcaat attagtttgt tcagcaacag
    31501 atggaccaat gccacaaaca agagagcata tactattatc aagacaagtt ggagtaccat
    31561 atatagtagt attcttaaac aaatgtgaca tggtagatga tgaagagtta ttagagttag
    31621 tagagatgga agtaagagat ttattaacag aatatgattt cccaggagat gacactccaa
    31681 tagtaagagg ttcagcatta atggcattag aagatccaaa gagtgagtgg ggagataaga
    31741 tagtagaatt attcgagcaa atagatgagt atataccagc tccagagaga gatacagata
    31801 aaccattctt aatgccagta gaggatgtat tctcaatcac aggaagagga acagttgcaa
    31861 caggaagagt ggaaagagga gtactaaaag tacaagacga agtagaatta gtaggattaa
    31921 cagaagcacc aagaaaagta gtagtaacag gagtagagat gttcagaaaa ttattagacc
    31981 aagcacaagc aggggataat ataggagcat tattaagagg agtacaaaga aacgagatag
    32041 aaagaggaca agtactagca aagactggat cagtaaaggc acacacaaag tttacagcag
    32101 aagtatatgt acttaaaaaa gaagaaggtg gaagacatac accattcttt gatggatata
    32161 gaccacaatt ctatttcaga acaacagacg taacaggagc ttgtaagtta ccagaaggaa
    32221 tagagatggt aatgcctgga gataacgtaa caatggaagt agacttaata aactcaatag
    32281 ttgtagaaga gggattaaga ttctcaataa gagaaggtgg aagaacagta gcttcaggag
    32341 ttgttgctac aataatagag taatccttta ctaaactaat ggatttaata taaaaaaaga
    32401 ggggggtaac tcctctcttt tttgtttttt gttgacaagt agcgctaaag catatatact
    32461 aaactagtgc cttgagacag attaacaatc aagtttaagg ttatgatgtt gtaatagaaa
    32521 ataaaattga aaaaaacaga aaaaaaactt gaaaaaatgt aacagatgat ataaaatata
    32581 atagtgtgct tgagagatta agaaaataat aattaaatcc tagtgaaata cgaactgata
    32641 tcgatttaaa agttacaaca cacccggagc agtgtatcgg tattggttgt acgcaacttg
    32701 aaaattaaac acgtgataaa ggagggaaaa caaaatggct aagaatgaaa aaataagaat
    32761 aagattaaaa tcatatgatc acaaattatt agatttttca gcaggtaaaa tagttgaaac
    32821 tgctaaaaag gctggatcac aagtttcagg acctgtgcct ctaccaacag aaaaacaagt
    32881 tgtaactata ttaagagctg tacataagta caaagactct agagaacaat ttgaaataag
    32941 aactcataaa agactaatcg acatagctaa tccaacacct aagacagttg actcattaat
    33001 gagattagac ttaccagcag gtgtagatat agaaataaaa ttataaaaac ccctaagata
    33061 ttatcctata gatgattatc ttagaatgat tactctaaaa gatgtaatcc gctgtaagaa
    33121 ttataggagg tgctaatatg aaaggaatat taggcaaaaa agttggtatg actcaaatat
    33181 tcactgataa aggtgtagtt atacctgtaa cagctgttga agcagggcct atggtcgtta
    33241 ctcaaataaa aacagttgat aaagatggat acaatgctat acaaataggt tttgaagatg
    33301 ctaaagaaaa agctttaaac aaacctaaaa aaggacattt agctgctgct aatgttttaa
    33361 agaaacattt aaaagaattt agagtagatt ctgtagaagg atacacagta ggacaagaaa
    33421 taaaagctga tgtatttgaa gcaggtgcaa aaatagatgt tactggaata agtaaaggta
    33481 agggattcca aggtccaata aaaagacatg gacaaagtag aggtcctgaa actcacggtt
    33541 ctagatacca cagaagacca ggttcaatgg gagcttgttc ttacccaggt agagtattta
    33601 aaaacaaaaa attagctgga catatgggaa gcgtaaaggt aacagttcaa aacttagagg
    33661 ttgttaaagt agatgctgac aagaacctta tattagttaa aggagctata ccaggagcta
    33721 aaggttcagt agtaactata aaagaagcta taaaggtttc taaataatga ctaacctaga
    33781 gaaaggagga ataacaatgc caaaattaaa tgtactaaat gttagtggac aaaacgttgg
    33841 agaaatagaa ttatcagatt ctatatttgg cgtagaagtt aatggacatg ttttatacga
    33901 agttgtaaaa aatcaattag caaataagag acaaggaact caatctgcta aaactagagc
    33961 agaagttaga ggtggcggaa gaaaaccttg gaaacaaaaa ggaacaggta gagcaagaca
    34021 aggttctaca agatctgtac aatgggtagg tggaggagtt gcttttgcac ctaaaccaag
    34081 aagctacaaa tatacattac ctaagaaggt aagaagatta gctatgaaga gtgctttatc
    34141 ttcaaaagtt caaaatagtg aagttatagt attagatgca ttaaacatgg atgctcctaa
    34201 gactaaagaa tttgctcaaa tattaaacaa tataaatgct gctaaaaaag ctttagtagt
    34261 tatagctgac aaaaacgata acgtaataaa atcagctaga aatatagaag gtgttcaaac
    34321 tgcattagtt aatactatga atgtatatga tatattaaaa tacgattcat ttataataac
    34381 tacagatgct gttaaaaaag tggaggaggt gtacgcataa tgactaatcc acatgatgta
    34441 ataataagac cagttgtaac tgagcacagt atggctgaaa tgggtgaaaa aaaatacact
    34501 tttgttgtgg ctaaagatgc gaacaaaact gaaataaaaa aagcagtaga aaaagtattc
    34561 ggagttagtg ttgataaagt aaatacttta aactacgatg gaaaagttaa aagaatgggt
    34621 agaactcaag gaagaacatc aagctttaag aaagcagtag ttaaattaac tgctgatagt
    34681 aaagaaatag aattcttcca aggaatgtag tattataaca aacgaaggag ggaaaacaga
    34741 tggctataaa aaagtttaga ccaacttctc ctgccttaag acaaatgaca gttttagttt
    34801 ctgatgaaat aacatgtaat caaccagaaa aatctctttt agttaactta aagaaaaatg
    34861 ctggtagaaa cgtacatggt agaataactg ttcgtcatag aggtggagga caaaaaagaa
    34921 aatatagaat aatagatttt aaaagagata aagatggtat acctgctaag gttgctacta
    34981 tagaatatga tccaaacaga actgcaaata tcgcattatt aaactatgct gatggagaaa
    35041 aaagatatat attagctcca gttggaatta atgttggaga tactatatta tcaggattag
    35101 gtgctgatat aaaaccagga aactgtttag cattaaaaga tatgccagtt ggtactatca
    35161 ttcataatat agaattaaag ccaggaaaag gagctcaatt agttagatct gctggagttt
    35221 ctgcacaatt aatggctaaa gaaggaaaaa atgctttatt aagattacca tcaggtgaga
    35281 tgagattagt aagcataaac tgtaaagcta ctataggtca agttggaaat atagagcatg
    35341 gtaacgtagt tatcggtaaa gcaggtagaa aaagacatat gggaataaga cctactgtaa
    35401 gaggttctgt aatgaaccct aatgaccatc cacacggtgg aggggaaggt agatctccaa
    35461 taggtagacc atctcctgtt actccatggg gtaaaccagc tcttggatac aaaactagaa
    35521 agaaaaataa agcttcaaat aaactaatag tatcaagaag aactaagtag taaatttatt
    35581 tttgctcgga aaggaggaat ataaatgtca agatcaacta aaaaagggcc ttttgtccat
    35641 gcaagacttt taaagaagat agaagctatg aatgctagtg gaaataaaga agttataaaa
    35701 acttggtcaa gatcttcaac tgtatttcca caaatggtag aaaacactat agctgttcat
    35761 gatggaagaa aacatgttcc agtatatata acagaagata tggttggaca taaattaggt
    35821 gagttcgttc ctactagaac tttcaaagga cataaggatg acgaaaaatc taataagaga
    35881 aaataattaa attatgacta agaaaggagg aataacaatg gaagcaaaag ctactgctaa
    35941 atacgtacgt gtatcaccaa gaaaagcagg ccaaatatgt gaccttgtta gaggaaagaa
    36001 tgttgatgaa gcattagcaa tattaaagtt tactccaaga ggagcagctt caataatagc
    36061 taaggttgta aaatcagcta aagctaacgc agaaaacaat cacgaaatgg atactgaaaa
    36121 attatatata gcatcaatag ttgctaatca aggaccaaca atgaagagat tcatgcctag
    36181 agctatgggt cgtgcaacta caataagaaa aagaacttct catatagagg ttgttgttaa
    36241 agaaaaaaaa taattaatag ataggaggga aagtaatggg tcaaaaggtt aatccacacg
    36301 gcttaagggt cggtgttata aaagattggg actcaagatg gttcgctact gataaaaaag
    36361 agttcggaaa cttattatta gaagaccata atatacgtaa attcttaaag aaaagattat
    36421 actcagctgg agttgctaag atagaaatag aaagatcagc taacaaaata aaaatggact
    36481 tacacgttgc taagcctggt gtagttatag gaagagctgg tgcaggaatc gaagcattaa
    36541 aagctgaatt agaaaaaatg acaaagaaaa ctataatagt taatatagta gaagtaagaa
    36601 gtacagataa aaatgctcaa ttagtagctg aaaatatagc tttagctata gagagaaggg
    36661 ttgctttcag aagagcaatg aaacaagcta tacaaagagc aatgaaatct ggtgctaaag
    36721 ggataaaagt ttctgcttca ggaagattag gtggagctga aatggctaga actgaaggtt
    36781 atagtgaagg aaatgtgcca ctacaaactt taagagcaga tatagattat ggtttcgctg
    36841 aagctgatac aacttatgga aaaatcggta taaaagtttg gatatgtaat ggtgaagttt
    36901 taccaactag agacggtgta aatccaagag aagaaagcag aaagagcgat agaagagaca
    36961 acaagagaga taatagaaga aacgatagaa gaggaaatga cagaagagga aatgataaca
    37021 gaggaaacta cagaggacaa agacctcaag gtggatcaag acctcaaaga actgaaaaca
    37081 aaggaaatta ataatagtta ggttcaagga aggaggaaaa atactcatgt taatgccaaa
    37141 aagagtaaag cgtcgtagag ttcatagagg aagcatggct gggcaagctc ataagggtaa
    37201 taaagttact tatggtgagt ttggattagt agcattagaa gcttcttgga taacttctaa
    37261 tcaaatagaa gctgccagaa tcgcgatgac tagatatata aaaagagggg gaaaggtttg
    37321 gataaaaata ttccctcata aaccagtaac aagaaaacca gcagagactc gtatgggtgc
    37381 agggaaaggt tctccagaat attgggtagc tgtagttaag ccaggaagag ttatgtttga
    37441 attagcaggt gtttctgaag ataaagcaag agaagctatg agacttgctg cacataaatt
    37501 accaatcaaa tgtaaatttg ttaaaaaaga agatttagaa gtaaagggtg gtgaatagga
    37561 tgaaagctaa agaattaaga gatttaacaa gcgaagagct aatgaacaaa ttaaacgact
    37621 tcaaaagtga attatttagc ttaagattcc aattagctac tggtcaatta gaaaatacag
    37681 ctagaataaa gtttgttaag aaggatatag caaaagttaa aactgttctt gctgaaagaa
    37741 agttatacga aactagagct taatttggaa aggaggcttt ttaaacatgg aaagaggaag
    37801 aagaaaagtt agaataggcc gtgttgttag tgataagatg gataaaacaa tagtagtagc
    37861 tgttgaagaa ttcgtacgtc atccactata taataaacgt gttaagagaa ctaagaaatt
    37921 caaggctcat gatgaaaaga atatatgtaa catcggagat agagttaaaa taatggaaac
    37981 tagaccatta tctaaagata agagattcag actagttgaa gttgttgaga aagttaagta
    38041 gtttttgaag aaggagggat tacgatatga tacaacaaga atcacgtcta agagttgctg
    38101 ataactcagg agctaaagaa cttttatgta tacgtgttct aggcggaagt aaaagaagat
    38161 atggtaacat aggcgacgtt atagttgcta ctgttaaaag tgcaacacct ggtggagttg
    38221 taaaaaaagg taaggttgtt aaagctgtta tagtaagaag caaacaaggc gtaagacgta
    38281 atgacggaag ctatatatct tttgatgaaa atgctgctgt tataataaag gacgataaaa
    38341 ctccagtagg aactcgtata ttcgggcctg ttgctagaga gttaagagac aatgaattca
    38401 tgaaaatagt ttctcttgct ccagaagtac tataattaag gaggtgcaat aggacatgat
    38461 gcgtgttaaa aaaggtgaca ctgttgtagt tatagcaggt aaagataaag gtaaaaaagg
    38521 ttcagtttta aaggtatatc ctaaaactag caaagtgtta gttgaaggtg taaatgtaat
    38581 aactaaacat caaaaaccaa gtgctatgaa ccaacaaggt ggaataataa ataaagaagc
    38641 cccaatacac atatctaatg taatgccatt tgatcctgaa acaggaaaag gcgttagagt
    38701 aagatatgaa gtaaaagatg ggaacaaagt aagagtatca gcaaagagcg gaaaagaatt
    38761 ataataaata ttgcttgaaa ggagggacct taaatggctt ctagattaca agaaaaatac
    38821 atgaaagaag ttgctcctgc tttaatggag aaatttggat acaaaaacgt aatggagata
    38881 cctaagttaa ataaaatagt tattaacatg ggtataggtg acgctagaga aaatccaaaa
    38941 ggattagaaa aaggcgttga agaattagaa atgatatcag gacaaaagcc tgttataact
    39001 aaagctagaa aatctgttgc taacttcaaa ttaagagaag gaatgccaat aggaacaaaa
    39061 gttacattaa gagctgacaa aatgttctac ttcatggaca aattagtttc agtttcttta
    39121 ccaagagtta gagactttag aggagttaac cctaatgctt ttgatggtag aggaaattat
    39181 gctttaggag ttaaagaaca attaatattc cctgaaatag aatatgataa aatagataaa
    39241 gtaagaggaa tggatataat atttgttact acagcaaaaa ctgacgaaga agctcgtgaa
    39301 ttattaaaat tattaggaat gccattttct aagtaagcaa aggagggatt cccgtggcta
    39361 gaaaagcgat ggttgttaag caacaaagaa agcaaaagta cgctactaga gaatacacta
    39421 gatgtactat atgcggaaga ccgcattcag ttttgaaaaa atttggtata tgccgtatat
    39481 gctttagaga attagcttat aaaggtcaaa tacctggtgt tagaaaagca agctggtaga
    39541 agcttgatta gaatggaagg agggcaacaa aatgacaatg acagatccaa ttgcagatat
    39601 gcttactcgt ataagaaatg ctaatgttgt taagcatgaa actgtagatg ttccagcttc
    39661 taatatgaag aaagaattag ctagaatctt attagaagaa ggtttcataa gaggttatga
    39721 tgttatagaa gatggaaaac aaggtatcat aagaatacaa ttaaagtacg gacaagaagg
    39781 cgaaagagtt ataacaggtc ttaagaaaat atctaagcct ggaatgagag tttacgctgc
    39841 taaccatgag ataccaaaag tattaaacgg attaggaata tcagttatat ctacttcaaa
    39901 aggaatatta actgacaagc aagctagaaa agaaaatgtt ggtggagaag taatctgcta
    39961 cgtttggtaa ttaatatgaa caatgtaagg aggtgcgacc atgtcaagaa taggtgttaa
    40021 gccaataata ataccagcag gtgttgaagt tactatagct gaaggaaatt tagttacagt
    40081 aaaaggtcca aaaggaactt taactaaaca attaagtgct gagttaaaca taaaaaaaga
    40141 agaaaataca ataatggttg aaagaccaac tgataataaa aaacatagat ctttacacgg
    40201 actaactaga actttattag ataatatggt tgtaggtgta aatactggtt tcgaaaagaa
    40261 attagaatta aaaggtgttg gatatagagc tcaaaaacaa ggaaagaaat tagttatgaa
    40321 cttaggtttc tctcatccag ttgagatgga agatccagaa ggaataactg ttgaagctcc
    40381 aaaccaaaca gagttaatag taaaaggtat agacaagcaa ttagtaggga attatgctgc
    40441 taagataaga gcttggagaa agccagagcc atacaaaggt aaaggtataa aatacgttga
    40501 tgaagtaatc agacgtaaag aaggaaaaac tggtaaaaaa taataccaaa acttaaacgc
    40561 tagaaaggag tgagctaggt gttaaaaaag gctgataaaa atgctaatag acttcaaaga
    40621 cataagagag ttcgtagaaa aataagcggt acttctcaaa gaccaagatt atgtgtattt
    40681 agaagtgcta acaatatata tgctcaaata atagatgaca caaaaagagt aactctagtt
    40741 gctgcatctt ctttagaagc agaagttaag agtgctgtca atcatacagg aaacaaggaa
    40801 gcagctaaga aagttggaga attagttgct aaaaaagctg ttgaaaaagg aatcactgaa
    40861 gttgtatttg acagaggtgg atacttatat catggaagaa ttcaagaatt agctgaaggt
    40921 gctagagaag ctggtcttaa gttctaatac gaaggaggga aaaatacatg ctacgtcgta
    40981 agccgataga tgcaggacaa cttgacttac aagaaaaagt tgttgaagta agacgtgtta
    41041 ctaaggttgt aaaaggtggt agaaatttca gatttgcagc attagtagtt gttggagatg
    41101 aaaacggaca cgttggtata ggtgctggga aagcaatgga agtaccagac gctataaaaa
    41161 aagcagttga agatgctaag aaaaatctaa tagtagtgcc aatagttggg actacaattc
    41221 ctcacgaagt acgcggacac tttggtgctg gaaatatatt aataatgcct gctgtagaag
    41281 gtacaggagt aatagctggg ggacctgcta gagccgtact tgagctagct ggactaaaag
    41341 acgttagagc taaatcttta gggtctaaca atccaagaaa tatggtaaat gctacaatag
    41401 aaggacttaa ttctctaaaa acagttgaag atatagctaa acttagaggt aaaaaagttg
    41461 aagaacttct agggtaagga ggtagtgtaa aatggctaaa ttacaaataa agttagttag
    41521 aagtgttata ggaactactc ctaaccaaaa aaagaatgtt gaagcgttag gattaagaaa
    41581 aagagaacaa gttgttgtaa aagaagacaa tgctcaaaca agaggtatga taaataaagt
    41641 aagtcactta ttagaagtaa ctgaaatagc tgaataattt ttataaagta gtgcaaggag
    41701 gtgcaatcca tgaagttaca tgagttaaaa cctgctgaag gtgcagtaag agctaagaga
    41761 agattaggta gaggtactgc aactggacaa ggtaaaactg caggacgtgg acaaaaaggt
    41821 caatggtctc gttctggtgg tggagtaaga gtaggatttg aaggtggaca aatgccacta
    41881 gctagaagac ttcctaagag aggtttcaat aacatattta agaaagttta cacagaagtt
    41941 aatgttgaag ttttaaacag atttgaaaat ggaacagaaa taactgcaga attattaaaa
    42001 tctactaaaa ctataagcaa aataggtaaa gacggaatta aaatcttagg tgaaggtaat
    42061 ttagagaaag ctttaactgt taaagctgct aaatttacag cttcagctca agaaaaaata
    42121 gaaaaagctg gtggaaaagc agagttagta taataacctg ctaatctcct agccagtaca
    42181 ggcggggtga attagcgtgc tgtcaaaatt aaaacaagct tggaagatta aagcagtaag
    42241 aaaaaaagta atgtatacac ttatgatgat cgtgatattc agaataggta ctactatacc
    42301 agttccaggc atagacacta gtattataca aaagatggta ggcggcaata gtctactttc
    42361 tctgtataat atgtttactg gtggagcatt tagtaacttt tcactatttg ctttaggtat
    42421 aagtccatat atcactgcat caatcataat acaacttcta acagtaggtt ttgaaagttt
    42481 agcagaactt caaaaatctg gtgaagaagg aaagaaaaaa atcaataagt acactaaata
    42541 tacagcacta gctctagcag ttgtacaagc tttgggaatt acattaggaa ttgtaagaag
    42601 tgctttaata tcaaatagtg tgttttttat cacaactgtt gtaataacat tagtttcagc
    42661 aagtatgtta gtaatgtgga ttggggacaa aattactgaa aaaggaatcg gtaatggtag
    42721 ttcagtaata atatttgcag gtataatatc aagaatacct acagatgtta ttaaaatatc
    42781 gcaacaagtt aaatctggcg aagttgcacc ttgggttata gtgattctag ctgtagttat
    42841 attacttaca gtaacaggag ttacatttat acaagaagca actagaaaga tacctgtaca
    42901 atatgctaaa agagttgttg gaagaaaaat gtatggagga caaagttctc atataccaat
    42961 gaaagttaac cagtcaggag ttatgcctat aatttttgct agttcacttt tagctttccc
    43021 tcaaacaata gctatgttta tgggtccaaa tgctcaggct tttgttcaaa aatacttaag
    43081 tatggcaaca gaacaaggat tttggacata tagatcaatt gagattctac ttataatttt
    43141 cttctcatat ttttatacaa ctgtatcatt taatacagaa gacatatcta aaaatatgaa
    43201 aaataatggt ggatttatac caggtataag accaggtgag cctactatgg attatttaaa
    43261 tagaatttta actagattaa ctttagctgg agctactttc ttagcaataa ttgctatggt
    43321 gccagctctt acaacacatt atatgaaagt aaatatgagt ctagctggga cttcattgct
    43381 aatcgttgtt ggagttgctt tggagcttaa gagacagtta gagtcaaact tagttatgag
    43441 aagctatcaa ggtttcttaa aataaaatgg agatggataa tatgagaata atattacttg
    43501 gacctccagg tgctggtaaa ggtactcagg cggcaggaat agtagaaaaa tacaatatac
    43561 ctcatatatc aacaggagat atattcagaa agaatataaa agagggaaca gaacttggaa
    43621 aaaaagctaa agaatacatg gaccaaggtt tattagtacc agatgagtta actgtaggtt
    43681 tagttactga tagaatatct caagaagatt gtaaaaatgg atttatgtta gatggatttc
    43741 caagaaatgt agcacaagga gaacatttag atatcttctt aaaaaatgct ggtatatcac
    43801 tagataaagt tgtcaatatt gaagttgata agagtatatt agtgtctaga gcagttggta
    43861 gaagaatatg taagtcttgt ggagctactt accatgttga gtttaatcct cctaaagtag
    43921 aaggtgtatg tgatgtatgc caaggagaat tatatcaaag agctgatgat aatgaagaaa
    43981 ctgtatctaa gagaatacaa gtttatttag atgaaactaa gcctttagta gattattata
    44041 gcaaacaagg tataatagca gatataaaag gtgatcaagc aatagataaa gtatttgaag
    44101 atattgtcgc agccttagga agtggaaaat aaatgattat cttgaaatca aaaaaagaaa
    44161 tagaactttt aagagaagca ggtaaaatag ttgctgacac tcatgaagtt ttaagaaaag
    44221 ctatttctcc gggaatatct actttagaat tagataaaat agctgaagag aatataagaa
    44281 aatacaatgc agaaccttct tttaaaggat atggaggttt tccaggaagt atatgtgctt
    44341 ctatcaatag agaggtagta catggtattc caggagaaac tatattacaa gaaggtgaca
    44401 ttgtaagttt ggatatagga gcctattata aaggatatca tggtgattct gcgaaaactc
    44461 acggagtagg catgatatct gaagaagata ggaaattgat agaagtaact agagaaagct
    44521 tctatgaagg aataaaattt gctaaattag gatatagact ttcagatatc tcacacgcag
    44581 tacaaacaca cgttgagaaa catggtttct cggtagttag agatttagtg ggtcatggag
    44641 ttggagcaaa tcttcatgaa gacccacaag tacctaatta tggactccca ggaaaaggac
    44701 caagacttag agaaggaatg gttattgcta tagagccaat ggttaatgca ggtcgttatc
    44761 atgtaaagac tctatcagat gggtggacga ctgttacaat agatggaaaa aaatcagctc
    44821 attatgagca tacgatagca attactgaac atgaaccttt gatattgaca aagttgtaat
    44881 ttaaaaagta ggtgaaaaaa gtgctatcag ataatttaag tataggtcaa gttgttaaag
    44941 tttcattagg acgagataaa ggaaatttat tctttgtagt caaaataatt aataatgaat
    45001 atgtattaat agctgatgga aaaaagagaa aacttgacaa acctaagtta aagaaagtga
    45061 agcacttaaa aaaatataat tttattaatg atgaagttag aaaaagagta gtatctggac
    45121 aagagattac agattctttt ttaagagctg aacttactaa gttaaattag ataatttaac
    45181 ttattgaaat ggagggctgg ttagttaatg gccaaaaaag atgttataga attagaaggt
    45241 acagtttcag aagctttacc taatgctatg ttcaaagtta aactagaaaa tggacatgag
    45301 atattatgcc acatttctgg aaagctaaga atgaacttca taagaattct tgaaggtgac
    45361 aaggtgaatg ttgaactttc tccatatgac cttacaagag gaagaattac ttggcgtaag
    45421 aagtagacta tattaatatt tagtctaagg agggattaat aatgaaggtt agaccatcag
    45481 taaaaccaat atgtgaaaaa tgtaaagtaa taaaaagaaa aggaaaagta atggttatct
    45541 gtgaaaatcc aaagcataag caaaagcaag gataagaaat tattactagc attttgttaa
    45601 attttatagt ataatactat attgtgatgt taacaaaaga acgttaaaat cgttgaacaa
    45661 tctggcgtag gattggcata tgatgtgaag ttttaaacac taaaaactat gtgtaggagg
    45721 tgcgatcatg gcaagaatag ctggggtaga tttacctaga gaaaaaagag cggagatagg
    45781 cttaacttat atatatggta taggtaaagc aactgctaac gaaatattag ctaaggctga
    45841 gataaatcca gatactagaa taaaagattt atcagaagat caagttaatg agttaagaaa
    45901 agttatagat gacgatttct tagttgaagg tgacttaaga agagaaattg ctttaaacat
    45961 aaagagatta agagatataa aatgttatag aggaataaga cacgctaaag gtcttccatt
    46021 aagaggacaa agaactaaga ctaatgctag aactagaaaa ggtcctagaa aaacagtatc
    46081 tcgtaaaaag aaaaaataaa taaataataa ctagatgaag gagggaaaag gaaaatggct
    46141 aaaccaaaaa agaaagttac acgtattaga agaagagaac gtaaaaatat agaacgtggt
    46201 catgctcata tacaatcaac tttcaataat acaataataa ctttaactga cgttcacgga
    46261 aatgctatat cttgggcaag ttctggacaa ttaggattca aaggatcaag aaaatcaact
    46321 ccatttgcat ctcaaatggc tgctgaaaca gctgcaaaag ctgcgatgga acacggacta
    46381 aaaagtgttg aggtattcgt aaaggggcca ggttcaggaa gagaagctgc aataagagct
    46441 ttacaagcaa ctggactaga agtaactatg ataaaagacg ttactccaat cccacataac
    46501 ggatgcagac caccaaagag aagaagagtg taattaataa gagtacaata ggaggtgtag
    46561 ataaatggca agatatacag gtgcatcatg tagacaatgc cgtagagagg gaatgaaatt
    46621 attccttaaa ggtgatagat gttatacaga caaatgtgct atagtaaaaa gaaactatgc
    46681 tccaggtcaa catggccaag gaagaaagaa agtttctaac tatggattac aattaagaga
    46741 aaaacaaaaa gttaaaagaa tatatggagt tttagagact caatttagaa atttatatga
    46801 acgtgctgaa aatatgcctg gtaaagcagg tgagaactta ttaagtttat tagagagaag
    46861 attagataat gtagtttaca gaatgggact agcatcttct agaaaagaag ctagacaatt
    46921 agtgactcat ggtcatttca ctttaaatgg aaataaagta gacatacctt cattaatagt
    46981 taaggttgga gatgttatag aagttaaaga gaaatcaaga tcttctgcaa aattcaaaaa
    47041 tttagtagaa gttaactcaa gaatagctcc taagtggtta gaagctaatg tagaaggaat
    47101 gacagcaaaa gtagttggtg ttccaacaag agaagatata gatcttgaga tagcagagca
    47161 cttaatcata gaactttact ctaaataata agcacacttt taaaaattat tttaaaattt
    47221 tgtttaccct cagtggatta ctgaatttta aggagggttt tgtccatgat agaaatagaa
    47281 aagccaaaag tagatatagt tgagcttagc gaagactata gatatggtaa gtttgttata
    47341 gagcctctag aaagaggata tggaataact ataggtaacg cattaagaag aatattatta
    47401 tcatcattac caggtgtagc agtgaatgct ataaaaatag atggagttct tcatgaattt
    47461 tcaacaatac ctggtgttaa agaagatgtt actgagataa tattaacttt aaaagagctt
    47521 tcagcaacta tagatggtga aggaagtaga acacttaaaa tagaagctca aggaccatgc
    47581 tctatcacag gtgcagatat aatctgtcct ccagatgttg aaatattaag taaagattta
    47641 gcaatagcta cattagatga taatgctaaa cttaatatgg agatatttgt agataaaggt
    47701 agaggttatg tttctgctga agaaaataaa acagagaatg ttccaatagg tgttttacct
    47761 gtggattcaa tatatactcc tgttgagaag gttagttatc atgtggaaaa cacaagagtt
    47821 ggtcaaaaaa cagattatga taaattagta ctagaagttt ggactaatgg tagtataaat
    47881 cctcaagagg gaatatcatt agctgcaaag gtattagttg agcatttaaa cttatttata
    47941 gacttaactg aacatgtaag tagtgttgaa atcatggtag aaaaagaaga agatcaaaaa
    48001 gaaaaagttc ttgaaatgac tatagaagaa ttagatttat cagttagatc atataactgt
    48061 ttaaagagag cgggaattaa tacagttgaa gaattagcta ataaatctga ggatgatatg
    48121 atgaaggtta gaaacctagg taagaagtca ttagaagagg taatacaaaa actagaagaa
    48181 cttggattgg gattaaaacc aagtgaagaa tagcgagcaa aggagggata agaatggcta
    48241 agtaccgtaa attaggacgt gaaacagctc acagaaacct tatgttaaga aacttagtaa
    48301 cttgcttact aagaagtgga agaatagaaa ctacagtgac tagagcaaaa gaaactcgta
    48361 gaatggctga aaagatgata actcttgcta agagaggaga tcttcatgct agaagacaag
    48421 ttttagctta tgttatggat gaaacagtag ttaataactt attcacagat ttagctccaa
    48481 aatatgctga gagaaatggt ggatacacta gaataataaa aatagggcca agaaaaggcg
    48541 atgctgctga aatggctttt atagaattag tatagtaagg aaaggattag gcttgatggc
    48601 ttaatctttt ttttattttt ttgactaagg tatgatataa taatgtgtaa aatgattttt
    48661 ataagttatt gcttactaaa aggagtatga gttaatggat aatatagtaa aggtaaataa
    48721 tatttcgttt gagtatatta cagatgaagc aaaacttaaa gcaatagata atttaagcct
    48781 agatgttaaa aaaggagaat ttgttgcgat aataggacat aatggttctg gtaagtctac
    48841 tttatctaaa aacttaaatg ctattcttat gcctactgaa ggaaatattc ttattgatga
    48901 tatggatact aaagaagaag aaagattatg ggatataaga caaactgcag gcatggtatt
    48961 tcaaaatcca gataatcaaa tagttgctac tatagtagaa gaagatgttg catttggacc
    49021 tgagaactta ggtatagaac caaaagaaat aagacgaatt gtagaggagt ctttaaaaag
    49081 tgtaggtatg tatgatttaa gagatagaca gcctcatttg ttatcaggag gtcaaaagca
    49141 aagagttgca atagcaggaa ttattgctat gaggcctaaa tgtataatat ttgatgaagc
    49201 aacagcaatg ttagatccat ctggaagaaa agaagttatg aaaacaataa aaagacttaa
    49261 taaggaagaa aatataactg ttatacatat aacgcacttt atggaagaag cagtagaagc
    49321 tgatagagtt gtagttatgg aaaaaggaaa gaaaatctta gagggaactc ctagagaagt
    49381 attcagtaaa ataaagatgt taaaggaaat cggtttagat gtaccttgta tgacagagtt
    49441 atctagttta ttaatagaag aaggtataaa tattagtagt gatatattaa ctgtggatga
    49501 gatggtgatg gaattatgtc aattatagta aagaatttaa cacatatata taatgaaggg
    49561 atgccttttg caagtaaggc acttgatgat gtttcttttg agattaaaga tagagatttt
    49621 gttggtctta taggtcatac aggctcagga aaatctacat taatacaaca tttaaatgga
    49681 ttactaaagc cttcctcagg agaaatattt ataaatgatt ttaatataac agataaaaac
    49741 ttgaatttaa ctgagattag aaaaagagta ggggttgtat ttcaatatcc agaataccaa
    49801 ttgtttgaag aaacgattga taaagatata gcttttggac cctctaattt aggcttagag
    49861 gagtctgaga tacataacag ggtaaaagca tcaatggaag ctgtaggact tgattatgag
    49921 ggatttaaag acaaatctcc ttttgaatta tctgggggac aaaagcgtag agtagcaatt
    49981 gctggagtta tagccatgaa cccagaagtt ctcatattgg atgaaccaac tgctggtctt
    50041 gaccctggtg gaagagatga aatttttaac ttaataaaag acttacatga aaaaaagaat
    50101 atgactataa tactatcatc acatagtatg gatgatatgg caaagttagc aaaaacttta
    50161 attgttatga atcatggtag cgtagaattt atgggaactc ctagagaagt atttaaatca
    50221 aatgctagta aattaaaaga tataggatta gatattccac aagttttaga gcttgcattg
    50281 aaattgagag aaaaaggctt tgacatcagt gaggatatat tgactttaga agaagcaaaa
    50341 caggaaatat taaaagttgt gagaggacga ggattatgtt aaaagatata actatagggc
    50401 aatactaccc aacaagttct gctattcata aattagatcc aaggataaag cttgtagcga
    50461 caattgtatt tatggtatct atatttgtag taaataaatt ttggccttat atagtagttt
    50521 tattatgttt attagctatg ataaaattgg ctaatatacc agtcaaatat attgttaagg
    50581 gtgttaaacc tcttaaatgg attattttgt ttacatttct tataaatatt tttttcttac
    50641 caggtgatga aatatggtca tttggatttt tagctattac aaaacagggt ctaagacaag
    50701 caatttttat ggcaataaga ttaatatttt tagtagttgg tacatcattg cttactttaa
    50761 caacttcacc aatagaatta actgatggaa tagagagatt gttgaatcca tttaagaaaa
    50821 ttggtttgcc agttcatgaa cttgcaatga tgatgacaat tgctttacgt tttattccta
    50881 cattgttaga tgagacagac aaaataatga aggctcagat gtctagaggt gcagattttg
    50941 aaagtaagaa tcttataaat agagcaaaga atttagtacc acttttggta cctttatttg
    51001 taagtgcatt tagaagagct gatgaattgg ctatggccat ggaggccaga tgttacagag
    51061 gtggacataa taggactaag atgagagagt ctgttatatc aagaagggat tatatggcat
    51121 gtgtatttca ggttgtttat ctgggagcaa ttatagctac tagatttata gcaatttaat
    51181 taataagtta tagatataat gaggtaaagt atgagaaata taaaaattaa aatacaatac
    51241 aatggtaaga attattgtgg atggcaaaag caacctgatt ctttagggat acaaggtaca
    51301 attgaaaggg ctatatatga tataacaaaa gaagaaacca gtcttatagg gtctggtaga
    51361 actgattcag gagttcatgc tattggtcag attgcaaatt ttaaaattaa ttcaggtata
    51421 agtatagaaa gtataccaat ggcactaaat gccaagttgc caaaagacat atcagttata
    51481 gaagcatgtg aagtaaatga tgattttcac tccagataca gtgcaaaagg taaaacatat
    51541 aaatatttag tatataatag caagtttaga aatccaatac ttagtgagat atcatatcaa
    51601 gtaaaatatg aacttgattt tgataaaatg tgttcagaag caaaaagttt attaggaaca
    51661 catgatttta aaggttttat gagttctggt tcatctgtaa aagatacagt tagaacgata
    51721 tatgatattg atataagtaa aaaagatgac ttgattactt ttgagattag tggtaatggt
    51781 tttttatata acatggtgag gattattgtt ggaacacttg ttgatatggg tcgtggcaga
    51841 attaacgaac catttttaga tataatacaa tcaaaaacta ggtcaagatg tggacataca
    51901 gctccagcac aaggattatt tctcaaaaaa gttcattatt aacttgacac accaggctac
    51961 atgtattaaa atatatgaga atgtgttaat aagtccactt gccccggact tgacataaac
    52021 ggtaaaaaaa ttttatgaaa agtagttaag gagggacagt tatgaaaagt tatatagcta
    52081 agccagctga tgtacaaaga aaatggtact tagttgatgc tgaaggaaaa acattaggtc
    52141 gtttagcaac agaaattgcg acagtattga gaggtaaaca taaaccaaca tttactcctc
    52201 acgttgatgg tggagatttt gttgttgtag taaatgcaga aaaaatagtt ttaagtggta
    52261 agaaattaga tcaaaaatat tacagatacc atactggtta tgtaggtgga ttaaaagaaa
    52321 tatcttacag agatatgatg gataagaaac cagaagaagt tatatcacat gctgtaagcg
    52381 gtatgttacc taaaaataaa ttaagaagca gaatgatgac tagattaaga gtatttgcag
    52441 gtgctgagca cactcatgca gctcaaaatc cagaagtttt aaactttaaa taagattaat
    52501 aggtgaaagg aggagtttat aatggctaac gttcaatatt atggaactgg aagaagaaaa
    52561 agttctgttg ctagagtaag actagttgca ggtgaaggaa atatattagt aaatggaaga
    52621 gcattagaaa attattttaa ttatgagaca ttaataagag atgttaaaca accattagtt
    52681 ttaactggta atgaaaataa atatgatgtt atagtaaaag ttgaaggtgg aggattcact
    52741 ggacaagctg gagctataag acatggaata tctagagctt tattaaaagc tgatttagat
    52801 ttaagacctg ctttaaagaa agaaggtttc ttaactagag atgcaagaat gaaggaaaga
    52861 aagaaatacg gattaaaagc agcaagaaga gctccacaat tctcaaaaag ataattactt
    52921 atttttttgg aaaagcaaaa tcctttattt actgttattc agaaagtatt ggtattttaa
    52981 aaatgttggg ttaagttaat tattgatata taataaaata ataagatatc ttattaggat
    53041 gtttttcatt aagaagaaca tcctttttat tttgactatt taataaa
//
LOCUS       DAEPXW010000014        53033 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.014, whole genome shotgun sequence.
ACCESSION   DAEPXW010000014 DAEPXW010000000
VERSION     DAEPXW010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53033
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.014"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            145..954
                     /locus_tag="KRM55_000844"
     CDS             145..954
                     /locus_tag="KRM55_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1593101.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            1099..1338
                     /locus_tag="KRM55_000845"
     CDS             1099..1338
                     /locus_tag="KRM55_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593102.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1525..1701)
                     /locus_tag="KRM55_000846"
     CDS             complement(1525..1701)
                     /locus_tag="KRM55_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593103.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1755..1851)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2206..2880)
                     /locus_tag="KRM55_000847"
     CDS             complement(2206..2880)
                     /locus_tag="KRM55_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH1593104.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(3100..3654)
                     /locus_tag="KRM55_000848"
     CDS             complement(3100..3654)
                     /locus_tag="KRM55_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1593105.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            complement(3732..4097)
                     /locus_tag="KRM55_000849"
     CDS             complement(3732..4097)
                     /locus_tag="KRM55_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593106.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4562..5347
                     /locus_tag="KRM55_000850"
     CDS             4562..5347
                     /locus_tag="KRM55_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1593107.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5444..6268)
                     /gene="pdaA"
                     /locus_tag="KRM55_000851"
     CDS             complement(5444..6268)
                     /gene="pdaA"
                     /locus_tag="KRM55_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH1593108.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEAEFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            6489..9608
                     /locus_tag="KRM55_000852"
     CDS             6489..9608
                     /locus_tag="KRM55_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH1593109.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     NFGNCNEYNNVSNYNLRWELNLQIYEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDLGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            9626..10225
                     /locus_tag="KRM55_000853"
     CDS             9626..10225
                     /locus_tag="KRM55_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBH1593110.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(10452..12581)
                     /locus_tag="KRM55_000854"
     CDS             complement(10452..12581)
                     /locus_tag="KRM55_000854"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBH1593111.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCNEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            12847..13095
                     /locus_tag="KRM55_000855"
     CDS             12847..13095
                     /locus_tag="KRM55_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593112.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            13261..14652
                     /locus_tag="KRM55_000856"
     CDS             13261..14652
                     /locus_tag="KRM55_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBH1593113.1"
                     /translation="MNFRDLFEKAIDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLVQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            14763..16232
                     /locus_tag="KRM55_000857"
     CDS             14763..16232
                     /locus_tag="KRM55_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH1593114.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLIVVINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            16297..16890
                     /locus_tag="KRM55_000858"
     CDS             16297..16890
                     /locus_tag="KRM55_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBH1593115.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            17072..18418
                     /locus_tag="KRM55_000859"
     CDS             17072..18418
                     /locus_tag="KRM55_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1593116.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            18600..18971
                     /locus_tag="KRM55_000860"
     CDS             18600..18971
                     /locus_tag="KRM55_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBH1593117.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            18964..19653
                     /locus_tag="KRM55_000861"
     CDS             18964..19653
                     /locus_tag="KRM55_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBH1593118.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            20173..21039
                     /locus_tag="KRM55_000862"
     CDS             20173..21039
                     /locus_tag="KRM55_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1593119.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            21281..22090
                     /locus_tag="KRM55_000863"
     CDS             21281..22090
                     /locus_tag="KRM55_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593120.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            22234..23298
                     /locus_tag="KRM55_000864"
     CDS             22234..23298
                     /locus_tag="KRM55_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH1593121.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFE
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            23326..24045
                     /locus_tag="KRM55_000865"
     CDS             23326..24045
                     /locus_tag="KRM55_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1593122.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            24069..24653
                     /locus_tag="KRM55_000866"
     CDS             24069..24653
                     /locus_tag="KRM55_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBH1593123.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            24655..26004
                     /gene="pabB"
                     /locus_tag="KRM55_000867"
     CDS             24655..26004
                     /gene="pabB"
                     /locus_tag="KRM55_000867"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBH1593124.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            25994..26737
                     /locus_tag="KRM55_000868"
     CDS             25994..26737
                     /locus_tag="KRM55_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HBH1593125.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            26771..27472
                     /locus_tag="KRM55_000869"
     CDS             26771..27472
                     /locus_tag="KRM55_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593126.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVVIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            27498..28070
                     /gene="folE"
                     /locus_tag="KRM55_000870"
     CDS             27498..28070
                     /gene="folE"
                     /locus_tag="KRM55_000870"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBH1593127.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            28134..28925
                     /gene="folP"
                     /locus_tag="KRM55_000871"
     CDS             28134..28925
                     /gene="folP"
                     /locus_tag="KRM55_000871"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH1593128.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            28936..29301
                     /gene="folB"
                     /locus_tag="KRM55_000872"
     CDS             28936..29301
                     /gene="folB"
                     /locus_tag="KRM55_000872"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBH1593129.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            29294..29800
                     /gene="folK"
                     /locus_tag="KRM55_000873"
     CDS             29294..29800
                     /gene="folK"
                     /locus_tag="KRM55_000873"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBH1593130.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEKLIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            29781..30566
                     /gene="aroF"
                     /locus_tag="KRM55_000874"
     CDS             29781..30566
                     /gene="aroF"
                     /locus_tag="KRM55_000874"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH1593131.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            30821..32611
                     /locus_tag="KRM55_000875"
     CDS             30821..32611
                     /locus_tag="KRM55_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBH1593132.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            32629..33795
                     /gene="rpoD"
                     /locus_tag="KRM55_000876"
     CDS             32629..33795
                     /gene="rpoD"
                     /locus_tag="KRM55_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBH1593133.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            33960..34649
                     /locus_tag="KRM55_000877"
     CDS             33960..34649
                     /locus_tag="KRM55_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1593134.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            34663..35760
                     /locus_tag="KRM55_000878"
     CDS             34663..35760
                     /locus_tag="KRM55_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH1593135.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            35823..36395
                     /locus_tag="KRM55_000879"
     CDS             35823..36395
                     /locus_tag="KRM55_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1593136.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(36455..36922)
                     /locus_tag="KRM55_000880"
     CDS             complement(36455..36922)
                     /locus_tag="KRM55_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH1593137.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(37308..37784)
                     /locus_tag="KRM55_000881"
     CDS             complement(37308..37784)
                     /locus_tag="KRM55_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH1593138.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(37904..38995)
                     /locus_tag="KRM55_000882"
     CDS             complement(37904..38995)
                     /locus_tag="KRM55_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBH1593139.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLIYESILYIHT
                     HKKAKKLKSEIYSKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     IIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(38988..39377)
                     /locus_tag="KRM55_000883"
     CDS             complement(38988..39377)
                     /locus_tag="KRM55_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1593140.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            39569..40015
                     /locus_tag="KRM55_000884"
     CDS             39569..40015
                     /locus_tag="KRM55_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593141.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            40279..41004
                     /locus_tag="KRM55_000885"
     CDS             40279..41004
                     /locus_tag="KRM55_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593142.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            40991..42235
                     /locus_tag="KRM55_000886"
     CDS             40991..42235
                     /locus_tag="KRM55_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1593143.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSGKYPNLESDIVDIITQGKSMENIDYGQKILSKYNYDKSIKINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFTSIYNDLSDMTKYVYYSSEGKPFDIKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            42315..42992
                     /locus_tag="KRM55_000887"
     CDS             42315..42992
                     /locus_tag="KRM55_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593144.1"
                     /translation="MEILRVENITKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            42993..45554
                     /locus_tag="KRM55_000888"
     CDS             42993..45554
                     /locus_tag="KRM55_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593145.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRRNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIKKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLFTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNEVIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAAIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            45588..46391
                     /locus_tag="KRM55_000889"
     CDS             45588..46391
                     /locus_tag="KRM55_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593146.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            46403..47533
                     /locus_tag="KRM55_000890"
     CDS             46403..47533
                     /locus_tag="KRM55_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1593147.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            47537..48946
                     /locus_tag="KRM55_000891"
     CDS             47537..48946
                     /locus_tag="KRM55_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593148.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYIIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKAEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            49157..49666
                     /locus_tag="KRM55_000892"
     CDS             49157..49666
                     /locus_tag="KRM55_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH1593149.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            51581..52936
                     /locus_tag="KRM55_000893"
     CDS             51581..52936
                     /locus_tag="KRM55_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH1593150.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT        21440 a         5305 c         8942 g        17346 t
ORIGIN      
        1 atattttaat aattaattat taggatgttt attttcctat ccttgtttta aagatttttt
       61 tagtatattc taatactata gtattataga gtaataatgt tgatttaaaa taaaaataag
      121 atttcggagg agtttattat ataaatgaaa gattactata aaataggaga gatatctaaa
      181 atatatggaa taggtagaga ttcattaatg tattatgaag aaataggcat tctaagacca
      241 gttagagata taaatggata tagaatgtat aatatatcag atatatggaa attaaattta
      301 ataaaagaat ttagaagctt gaactttcca atgaagaaaa taaaagaata cctagatgac
      361 agaagtatag agtctacgaa aaatatttta aatgaagaac tcgatttaat tgataaaaaa
      421 atagctgaat ttataagcca taaggaaaat attataaaaa gattgagttc gattgaaagt
      481 gtaattcaaa atacaaaaat agatgagata gaggttgtat atatagaaaa aagaaaagct
      541 ttagaattaa atgctgatat aaagagggat gaagacttcg attttttaat tcaaaaactt
      601 cagaaagaat atgaagatag atttaatata cttggaaata acaatattgg ttctgccttt
      661 tctactgaag caattaataa aggtatattt aatgagttta aatctgtatt ttgttttctg
      721 gaaagtaatg agaaagtata taatatagtt tttgatgaag gatattatgt aactttaaat
      781 tatactggga gtaattctaa taataagatg tatatggaga aggtgtttaa atttatagaa
      841 gaaaacaatt ataagataat tgctgaccct atagaaatct acaagataga tatacatgag
      901 actggaattg tagaggagtt tgtaacggaa attcaagttc ctataactaa atagctatat
      961 ttcaatggat tagatggtaa atagaatgaa aaaatgttga tttgccaccg atttgtcact
     1021 gtgttataaa atcggtagca aattatattt taaattataa gatagcatga aaaaataatt
     1081 gtttaggggg ttataaatgt gaaatgttct aattgtggaa gtgtaaatat tgaaaaggga
     1141 attttaacaa ctggtggcat atatgctgaa actattggat taaaatatag aggagatgga
     1201 aaattagata aagttataaa taaaactttt ccagtacaat ctactatata ttcagattta
     1261 tgtttagatt gtggagaaat agttagaacc tatataaagg ataatactga taggaattgg
     1321 tgtaaagata agaaatagaa taatttttga agtatattaa tatttgaagt tgaattttat
     1381 taaagataca agtgaaaaag tataaatggg aagaaattgt tgtatggaag aaactttgca
     1441 tataggggag attagttttt taatataata acatttttaa atgtagataa aactaaaaag
     1501 ggttctctag aaaacaattt ctatttaatt atacttactt accaatacca tcacttgatg
     1561 taaacaagat tctactacat tttctccgta ctctagtata aaatcatcta gctgtgtatc
     1621 tataaaatca caataatcat ataaactact aatataagca gttaacatgt gtgtacattt
     1681 atccatttca tctctaaaca tatatattac tatcccccta aaaaactttc ataaaacaaa
     1741 aagaacaata tctttttggc aactggctga cataactcat agtttatttt ataagcgtta
     1801 gtccctatag ctttgcgtca ctaaatttct ctagttttgc cgatttagtt ttattctaca
     1861 actaaaataa tacactagga taagttattg ttcaacatac ttgtcagaaa attgaaatat
     1921 ttaacaatat cttaacaata tgaaatctat ttttcactca agaaacaaac tatatgtata
     1981 gaatgtttaa taaaaattat atttagtttt gtattgaagt ttttatatta aaaagtttag
     2041 ttcacaagag ttacttggct agataataga tgaacaaaaa tatcttgaaa aaatatatat
     2101 gaatggcaaa aaacaaggga tgaattttat atagactcat cccttaatta tttatatatt
     2161 gaccttgatt aaatatatta ttatttttaa gcttcaattt ttatattata tttctaaagt
     2221 ttctataaga ggattatcgc taaataattt taataaattt gtttttttat atcctttagg
     2281 taacttagta tatataacta cttctaacca atccccatca aggcgtttaa tattcatgtt
     2341 tataatttca atattagatt ttttaaattt accttcaata tattctatgg aatcagtgct
     2401 gttagaaatt ttaagagaaa cttgctctgc tgtagggagt ttcatccatt tcctatctct
     2461 atgaagtgtt atctgtacaa taacaataat gatacttgaa acaataccaa ctaagtataa
     2521 tccagagcca atggcaagac ctgtaccggc tgtggcccat ataccagcag ctgtagtaag
     2581 accacttact gattgatttc taataaatat taatccagca cctaaaaaac ctataccact
     2641 gacaacttgt gctgcaacgc gggctgggtc tagaccaata cctggagtac ccactatatc
     2701 attaaatcca tacttggaaa caatgattat aagtgctgaa gctaatgcca ctataaaatg
     2761 agtgcgtatt ccagcttctt ttagtctatt ctttctctca tatccaatta aagccccaca
     2821 gaaaccagca gtaatgattc ttgctatata ttcaaattga atcaatatat gatggttcat
     2881 ttatctagca cccccttcta tataatatta tatatactat aatactacat tttttatgtg
     2941 aatatagtaa agtttaaaat ttatataata gttatatatg aatataaaat gtataaacgt
     3001 atattatgta tataaaaatg atagaaagca tctaatttta aatgattaaa gagcaagctt
     3061 aaataaatca aacttgctct tttaacatag tgtatgtttt tatttgtgat agttagataa
     3121 aaatttatct gtgtttttta catctgcaaa actgttctgt agtgatgcca tgaatacttg
     3181 atgtacagta tttgcattaa tttctatatt attccaagat aaattcttcg ttgtacatgc
     3241 atcgcttatt agagttatgt cgtatcgaag tttctttgct gttcttacac ttgtatcaat
     3301 acacatatgg ctcatcattc cacagattac tagattagta atattttttt tctcaaggat
     3361 actttgcaaa tctgtttcaa agaaactatc tggtgtgtgt ttaattataa tttcttcatt
     3421 atctagtgga aaaacaattt tatttatttc tgaaccatga gtattaggaa gaaaaaaaga
     3481 agctgtttta tctgttgata tatgctgtat atgaataact ggtaaattgt tttttctaaa
     3541 aaacagtagt atttttttag cattttcagc agtttcttct gattgaaata attcacattt
     3601 tccattttta aaataatcat tttgaatatc aatcaatatt aaagctatag acatgattat
     3661 acctcctatt tatttttatt ataatactat tgtaaaaaat gtaaattact tactttttgg
     3721 tatgtatagg attacttatt gtagcaaatt cctttattat ctagaatttc ttgttgacca
     3781 tgttcaagca tatattcgat tcctatttct tgcattattt ccactgcttt taacattttt
     3841 ttaccacgat tagtaagaaa atattcaaca tgtaatggat atccagcaga acttatttta
     3901 tcaataatcc caaaatcacg taactctttt aattgttgaa tcaacatttt ttgatttatt
     3961 ccataaatat tatgttgcaa ttcagaaaat gttttattag attgtcttaa ttcaaatata
     4021 aggatagttt tccattttcc tttgattatg tcatgtacaa tttcaagagg acatgtatat
     4081 tcagctctta ttttcatagc atatcacccc cagtaaaatg ataataaatt atatcacttg
     4141 tcttgtgata tgacaaatat atatgaactg tatataaatt ttatgtttta ttaagttcta
     4201 aatttcttct attgtagttc atatttagta cataaataat tagtaagata taagtaaata
     4261 aatatataac atgactatag aaatttaact ttaaaataac ttatgataat ttagaggagg
     4321 aatatatatg aatatatcaa gaaaagctat gaaaataata gaattagcac aaaaaattgc
     4381 aaataagaga ggtatttcag tagaagaagc ttggagtgaa gcagtaacag aatataaaaa
     4441 taaatacgaa catattgcat agatatttaa aaatttagaa tatttggtag aatataatga
     4501 ttttaaatga tactataaat tataaggtat atcattatta acatagaagg aggatatctg
     4561 cttgattgta aaaatagata atactttaga aaaagaattt tggcaatatg tatcacatga
     4621 agaaagttta aatttattca taattggata cgttgagaat tatggattta gctctcaata
     4681 tcaagatata tggtctcagg tagaagatgg aaatataacc tctataatat taaaaaataa
     4741 gtcaacactt ataatttata gttttaaaaa taattttaat ataggagaaa tgaagaatca
     4801 tataaaagat ttagatgtag aaagcataag tggaaaaaaa tgtgtaatag atagactaat
     4861 aagtaaatac aaagattttt atgaaaaact agataataaa ttttgtgtat taaaagaaat
     4921 aaaagaaata gatttttcca acatgaagga gtataaaata gaaaatgctc aggaaaaaga
     4981 tattgatgaa ataggaaaac ttttaaatag gtcagactat aaagtaagta aaaattacat
     5041 agaagaaaga aaagttcatt taaaagaggg aaatgtaaga gcatatttta ttagaaatga
     5101 tgatactatg attagcactg tgtcaactgg tatggaaact agttttttgg caatggtggt
     5161 ctctgtaagt acagataaaa gatatagggg aaaaggactt gcaagttata tggtttacaa
     5221 tttgagtaaa gaattgttgt tagaaggaaa agttccatgt cttttttata ataatgatgt
     5281 agcaggtaaa atatatcata atataggata caaagagata aatgaatgga caattctttt
     5341 taaatagcta taaaaaataa aaaactctat cgagaattaa agtatttata aataactata
     5401 tttttactat aattcatgat agagtttttt aaaatttatg atactatttt ttattattta
     5461 aataatcaag tgttttaagt ttataacctt ctttttccca atgtgtaaga acctcatcta
     5521 atatctcagt atttgttgat gaatttggat gcagtaaaac tattgcacca ggatgagttc
     5581 ttgaataaat tttgtttttg gcaaattcat gagtaggttg tttcttttca taccaatcta
     5641 cataagcaaa actccaaaat attgatttat atcctaaatc ttgtgtatat tttaaagatt
     5701 gttcgctaaa tttacccatt ggaggtctaa aatacttagg catttctttt ccagtaacat
     5761 ctttgtatgc tttttctaca cttgtaattt cttctttgaa tttttcaaaa tctgtaatac
     5821 ctgccattga tggatggctt tttgaatgat tacaaactaa atgtccttct ttttccatac
     5881 gctttattaa ctctggattg ctttttatat aactttcaac tacgaaaaat tgagctttag
     5941 cattgtgttt tttaagcgta tctaataatt ttggagtgtt tccactttca tatccagcat
     6001 caaatgatag atatataact ttttcattgg gatttcctac ataataagct ccgtattttt
     6061 taaaaaattc agcttctttt ataggtgatg gctgtttacc atcctcccta gggttaaaat
     6121 accaatcata ttcatgtgtg tcgagtgttg gactagaaat ttgagttttt gttttatcta
     6181 atgatttaaa atttatacta gcaattccaa aaagtattag agcaaatgct cctatcataa
     6241 tgtatttttt taggctatct tttttcacaa tttcacctct tatttaaaat ttaaagtata
     6301 tttcttataa tatagtttga atatttatag ttaaaaatat tcacatatac aaataataaa
     6361 tgaaagaagt ttactgtaag atataaagtt gatattaatt atcttaaata aagtgtatat
     6421 aaatgataaa atataaagag aaatgattgt aaataagtta ggctggttta acttgaaggg
     6481 atataaaaat ggataatata ataagtgtat tgaatgatgt tgttttttta gatatagaag
     6541 ttagtggatt agattgttta aattcagaaa ttttagaagt tggagctgtc aaggttaaag
     6601 attggaaaat atatacctat gaatcattaa taaaaaacaa atttgaggta cctatagaag
     6661 tattctcagt atgtaaaaat ttagataaaa atgatttaga aatagctaat gaaatagaac
     6721 tggtggaaga tagacttgta aattttgtag aagatagttt cattatatgt catgatttaa
     6781 gtctgaaaaa aaagtttttt gagtatcata tgccaaagtt aaaaaacaaa tttattgatt
     6841 taattgaatt agcagttatt ttagaaccat atcataaaga ttatagctta gaatacttaa
     6901 aaaatacttt aacaaattgt aattctaaag tggaaaatag agctttatca gatgctattg
     6961 atataataaa tattgtaaat tgccttttag taaaatttaa taactatgaa aaaactactt
     7021 tggagccatt gagttttaaa ataaattcat atcttaaaaa atttaatctt ccaacatggg
     7081 aatggagcaa atttttagaa gaggcaaatt atgatttatc aaataatata aatataaaaa
     7141 aagaatataa tatatttgac tcaaaagaag aaaagaagaa ggaaagagaa accttaaaaa
     7201 ttttaaatga agaagaaaaa aattatgaag aattattaaa atacaaaact atttgggaga
     7261 ataaagaagg atttacatat gaatatagac ctggtcaata tgagcttact aaaacaataa
     7321 gagagttgtt tagaaatagc gaagatgaag aaaaaattgc atgtatagag gcaccaactg
     7381 gtataggtaa aagtgtagga tatttattgc ctgcaatatt agaggctaga attaataaaa
     7441 aaagattatt aatttctact gacacaaagg aattgcagat acaattaata aataaagata
     7501 ttccaaatgt gttagattct ttgggtctaa atggaaaagt aagttatgga tatataaagg
     7561 gaaaaaataa ctatatttgt atagatagac tggaagcata tatagatgat tatgagtctc
     7621 aaaaccctac taaaggagaa attttatctt taatattttt gaagagatta gttgaaggtg
     7681 gcaagtatgg agatatagaa gaaataaatt atttagtgtt tgacaacttc aaggaaataa
     7741 gtactcactt aagaaatgta agttgtgacc caaatatgtg cagacctaaa aaatgcaaaa
     7801 aagattgttt atataaaaac agaatagaag aattaaaaga agaacatata acagtagtaa
     7861 atcattcact attagctaaa tggccgtata aggatgaaaa acctttagaa aatataatag
     7921 tagatgaagc acataatttg actgaaaaag gatatgattt cttttcaagt attataaatt
     7981 caaagtcttt aaggtactta ttacaagaaa tttatcctta cgagtttatt caaaatagta
     8041 gctttatata taaaaaatat agtagaaata tgagaaaaat aaaggctttt gataaatttt
     8101 ataatgtatt aaaaattgga agagaagata aacaaaaaat tgctagaagc ataaatctca
     8161 ttattgaaga gatagattca atattaaatt ttggtaattg taatgaatat aataatgtaa
     8221 gtaattataa tttaagatgg gaactgaatt tgcaaatata tgaaattgtg ggaaaactaa
     8281 aaaaggatgg tatagatact gaaataagtt atagagccta tagtgaaaag ataaagttga
     8341 gttgtgagaa aataataaaa aatttagttt caataataat aataatttat aggaatattg
     8401 atgatgatag tatagataaa gaagcagata tatataaatt tggaaaggca aagacaagag
     8461 atttagagga tataaagatt atatttgaaa tctttttaga gtatgatgaa aaggatgatt
     8521 atgcaaggat agttgaaatt gataagaatt ataatgactt tgaatttcga gtagtgccat
     8581 taaaaatagc agatttattt gaagaaaata ttttatctca attagaaaaa ggaatatttt
     8641 tatcagcaac tttgagttta tctgaaagta tgtcttattt taaaaataca ttaggaatag
     8701 acagagttaa gaatgtggaa aagattatag aaccaatttt tgattataaa aatagagtct
     8761 ctgtagttgg attttctgat atttgtgagt acagaaattc tgaatttcca aatgagatga
     8821 gtaaaattat atctaatata tcaaagatta cagaaggtca tacattagct ctttttaata
     8881 gtaaagatag acaagaaaaa acttatgaaa tattgaaaaa atacttacat agttttaact
     8941 tagaaattta tgctgataaa aagggcatta gacaccttaa tgatttaaat agaaaatgtg
     9001 tagtacttgg ctcaaaagga tgttttgaag gcgtagacat tccaggggat ggtttggttt
     9061 gtgtaacttt agacaagctt ccgaatctaa atccaaaaga ccctttgtat tttactataa
     9121 tgaagaagta tggtatagac tactatacta taaattatcc tcaaatgacc ataaaggtaa
     9181 agcaagctat ggggagaatt ttaagaagca aatatgacta tggatgtttt gtgatttttg
     9241 atttaggaac taatataagt gttttaaaga gattagagaa agatttacac gattgtaaaa
     9301 tttcaaaggt taatagcaat gagttttata cttatataag gcgacattta aataaatcta
     9361 gaagtttaat actaaaatct gttatatttg atactataaa agcgttgaat gttgatgcta
     9421 aaatggataa caatgatgtt gataaggata ttataaaaaa agatataaat gaaaatataa
     9481 gacaaagagc tgtaaaagga gaagtgtacc atattgatat tataaaaaaa gatatgaaag
     9541 taaaatattt tgatagaaac tatcttataa atttagatat atttatgaga gaagaagata
     9601 aaaattaaga gtgggagtga tatatttggc aaaacaaaag ttttatgctg tgaaaaaagg
     9661 taaaaatata ggtgtatata atacatggga tgagtgcaaa aaacaagtaa atggattctc
     9721 aggagctgaa tataagagtt tttctacttt tcaagaagct aaagaatata ttgatgggtc
     9781 agaaaaattg agttttcaag aagataagga gtttatagaa gcatatgtag atggaagtta
     9841 tgaacattca gtaaaaatgt atggttcggg tgttgtgatt ttaaaaaata atgaagttat
     9901 aaaaacttat agtgaaaaag gaaaagagaa aactttagta agtatgagaa atgtagctgg
     9961 agagatagag gcttctaaaa ttgcaatgca gtactgtatt gacaataatg ttcaaaactt
    10021 gattttatac tttgactatg aagggattga aaagtggtgt actggagttt ggaaaacaaa
    10081 taaagaagga actatagcat ataaaaattt ctatgacagt attaagaata agcttaatgt
    10141 aaaatttaca aaggttaaag ctcattctgg aaataagtat aatgaggaag ctgataaatt
    10201 agctaaaaaa gctattggtg tataataaaa aaatatttat acataattac atggtataag
    10261 agtatatcta aattcctact ttataattaa acaacttata attaaataaa ttttgattaa
    10321 aaaagcagat tgtattatga aaaaataagt atctaattta taaacaatta ataatagtat
    10381 taattagata caacttattt aatataataa aatctgcttt ttatataact ataaaatttt
    10441 actacattct attagaattg cccataaata ccttcaagtt cttcttttaa tacttcaggg
    10501 tcatttatac caatagacat ggttctagcc agtatatttg cttggtcata agttgatgtc
    10561 catgagaata caccacctag acaatttcta agaacatatt gagtttttaa gaatattgat
    10621 aaagcatcat catatgacat tgcaaaatct ccatccttaa ctaaatacgg aacttgagca
    10681 gtattatcaa atctatattc atatccattt ttatttatat aatcccttct aagctcatca
    10741 taagttcttg ttatagtagc acctaatctt ccataaaatg gtataccgag aaggattttt
    10801 tcagaaggca ttccagcatt ctcaagattt cttaccattg catcaacact atatcctggc
    10861 aaagataagt ctgaatcaaa aagatttgct tgatgttttc taccatttgg gcctgtttca
    10921 cctgctgtaa aatcataact cataagatta aaataatcta ttataggagc tattttatct
    10981 atttcagcac ttgaatttat atatcctcta tctcctgttc cagctacact aagccattta
    11041 tcatctccta taacatctct tatggcagtt agtaagagtg taaagttttc tctatcttga
    11101 ggtcttgatg ttattccaga tgcactactt ccaggatatt cccagtctat atctattcca
    11161 tctaaagcat attcatttat catctgattg acctgtcttg caaaattata tctagatgta
    11221 ggtgttaatg ctgcatcaga gaatccttca gctccccaac ctccaatagc tacaattact
    11281 tttaagctag gtttttcacc tttaagagca agtaattgat ttaaaaatct aggataagga
    11341 ataaacaaat ttccagactg gtctatctca gcaaaagcaa atataactgc atctaatagt
    11401 tgagcatcta cattagttgg atttccaaga acatattctg ctacaattgg atttatatct
    11461 ggacagtttg cattttcaac tattggattg tatgggtctg ttatttgtgg tctaactaat
    11521 tttttagaat cttttaaagt tttcatagct atttttttag tatttttttc gctagtataa
    11581 tcgtagtttt tataattatg tttatagaaa tcttcataac tactatcttc tttgttatag
    11641 ctagaattta ttttgtcaca agattcatct ttatcatagt taaaattcat ttcattacaa
    11701 gacttatctt taaacttatc ttgtttggag ttgtgaacct tgttagtatt tttagtatgt
    11761 tttttctcat ggttgcaatc atctttaata tcagtcttgt gttcttgttt acagtcaaga
    11821 gctttgttca ggtagtcatg atgttcatgt tcacagttac attcattttc aatgttttta
    11881 gtatgttctt ttttccagct acaagtatta tcaattttct tgctcacttc ttcatcatta
    11941 taattatctg gtacaaaaca taagtaccag tccatacatg aatatttctt attacaactg
    12001 ttaactctat tttttaattc cttatagttt ttaggataag gtaaaatcac tggcattcca
    12061 ggaaaccagt ttgcaggagt aactatatta tctctatcac tagtctgaag tgcatctact
    12121 attctaagta tttctggaat atttcttcct gtagttagtg gataataaag aatcgttctt
    12181 agaatttgat tattatctat aataaataca gagcgaacag ttgatgtatc actcattggt
    12241 tttgatatca tgccgtataa cttggcaatt ctcatatctc tatcttctat aataggaaat
    12301 ggaatttcta cacctgtaag taaagaaata ttatacatcc aagctaaatg tgaactgtta
    12361 ctatcaacac ttagaccaat tagttctgta tttctttttt taaattcgtc ataatattta
    12421 gcaaaacata aaaattctgt agtacaaact ggtgtaaaat caccaggatg tgaaaataaa
    12481 acaatccaat tacccttata gtcagagagt ctaataggac catttgttgt attggcttta
    12541 aaatcaggag cctttgaccc taaacttggc aaatttggca tgtaaatcac ccctcaataa
    12601 attatcattt attttattct attaattaat acatattagt gttactattt tattaaaagt
    12661 taagtaatcc ttatgtcaaa aaaagatatt tattaaaaag atttaatatt ttcctaatat
    12721 aaatgacaat agtaattgct atttttttac taatttggta tagtaatgga taaggggtag
    12781 tgtcaatttt agtgattata cgaggtgagt ggattgaaaa aaattctaag aattttagtt
    12841 atctccatga tgatatgttt tgcaatgact tttgcattag tgttaataaa ttcagttatg
    12901 ggagtacata taggattgga ttattacttt ttgatgggaa gtgtgcttac agtttgttta
    12961 acaattggaa ttgttttatg caatgctaga aaaatatttg atagcaaagc tatacacaag
    13021 acaagaacga aaactgtcag taataataaa aaacaaaaga gtcattctag ggatataaaa
    13081 agaaagatat cataatttat gtaaaggaaa tatttatgta taaaataatg attgataggt
    13141 aaaataaaaa cacgatttaa cttgtgtttt tatttttttt caagaattat gatataataa
    13201 ccaataagaa atttagttta ccataaaata taaagattat taaatggaga gggaactata
    13261 atgaatttta gagatttatt tgagaaggct atagatttta ttgatgaaaa aaggaaatct
    13321 atagttgcga tttcattatc aacattaggt gtaattgctt tgataatagt atttttctta
    13381 agtagtaacg agtttagtgt aggaaatgaa gctaatgagt tgttaaagat tatagagaaa
    13441 agacagtatt ctatagctgt tgattactac acaagtatag aaaaaaagtt ttctgattca
    13501 aaaatggaaa ggtttaataa gtctgtttct aaaaaaataa ataaattgct attaaatagt
    13561 ggtgataaat atttagatgg agacataagt caagaaagtt ttattggatt aataaatacc
    13621 gtgaaagaat taaacaaaat aagtatagat gtggatgact tattagttca agctgataga
    13681 gttagagaaa tgtataaaga agaaaatact acttatgata ttgccattaa ctacataagt
    13741 actgtttcaa tattaaatgg tatgggtagt aacctagatg tatacaaaca gaatatagaa
    13801 acaatcaaag agtctagaga tgtttatgac tcagcagtaa aagaccaaaa agcatataag
    13861 tattatgaag ctattgaaaa gtataataaa gtattaaaag aagatgaaaa gtattacagt
    13921 atggctcaaa atgggaaaga acaatgtatt gaagaaatgt atgattacta tataagtaga
    13981 gctgaagagg caaatacttc tggagattat gaaagagcat tacaatatat tgagtattta
    14041 aaagacgatt attcagatga tgaaaaggta cagagtttag aaaaaaaata taaaaagaat
    14101 ttatcattgt atactttaac atctgatgac attataaatg taatagctaa aaaaagtggc
    14161 aaagacaagg caaatctatc tataaattca cttccacaaa tgataaaaaa taataaatac
    14221 tattatgctg aagtatatga gtatgataaa ttaataaatg aagttttggt aagtgcaaaa
    14281 actaaagatt tatattcata taaagatggt aaaaaagatt acaaagtaga ttatggtgat
    14341 ggatacttta gaatattaga agatggaagt tatcaatttg gtattacaaa agataaagct
    14401 aagtttgtgt taactaatac tctcgatgaa aaagaaaata agtataaaaa gattgagata
    14461 ttagatatag agaaagcaga tagatatgta aaaagtaaaa agagtttaga agaattgttt
    14521 ggaaaatata aaaatattta ttattatgct gtagtaaata aaggcttatt tagaggcaaa
    14581 gaagtttatg ctattaatat ttacaatgaa aaaatatatg ccatatcaga aaatggacta
    14641 aatgaatatt aataatatta aattaatata taattaaaaa gtttttgggg ttttaaggcg
    14701 cattatgtag taatataata atagggatat ataaataatt ttattgtaag gagaagtatg
    14761 ggatgagtaa tgtgaacaaa aagctagtta tagctattgg agctgtagca ttagtagtaa
    14821 taatttttat aggcataatg tgcatgcaat ttaaagggga gaaaatagca aaaaacacat
    14881 atgttaatgg agtaaatatt ggaaaattaa ctaaatcaca agcaaaacag gaattagcta
    14941 aaaaatacaa attagagaat gttgatttta attacaatga taaaagttgg aaagtaaaga
    15001 gcaaagattt aaatttatct actgacctgg ataaaacagt agaaaacgca tataatttaa
    15061 atagaaagag tgctttcttt ggcaatctat caaaaactat ttcagcaaat tttggcaaaa
    15121 aaagcaactt aatagttgtg ataaattatg ataaaaataa attaaaagca gaaatggaaa
    15181 agatagctaa agaaatagat gtagatgtaa aagatgctac acttgatata agtggtgaaa
    15241 aagtcaaggt tataccagat tctgatggtc ttaaaatgga tatttctaag agtatggaga
    15301 attttgataa tcaaactaaa aaaggtaact ataaaaatga gttagtagta aaagctactc
    15361 cagcaaaagt aaaaaaagag caacttgcta atatagatac aaatttaggt acgtattcaa
    15421 caacatttaa aacttctcaa ataaatagaa gtataaacat aaaattagca acagataata
    15481 taagtaatgt attacttatg ccaggagaaa ctttctcatt taataaacat acagggaaaa
    15541 gaagtaagga aaatggatat aaaagtgcac ctgtaataat ggaaggtgag atggaagaag
    15601 attatggtgg aggagtttgt caagtttcat ctacgttata caattctgtg ttatacgcag
    15661 gtttagaaat tgttaatgta aaaaatcata ctataccatc aagttatgtt ccaaaaggaa
    15721 gagatgcaac tgttgcagat agtggaatag atttcttatt taaaaataat ctaaagcatc
    15781 cagtttacat aaaaaattac gtttcaggaa atcaaattgt ttgcaatata tatggaagtg
    15841 cagaagataa acaaaatata acaatatcaa caaaattaga tggcgtttca caaactacaa
    15901 tgaaaagagt taatgaccct acaatgccta aaggtaaaga aaaagtagac aaaagtggaa
    15961 gaaatgcata ttctgtatca acatatagaa catttaatga tgcaaatggt aaaaaaatta
    16021 aaactgaaaa aatagctaat tcatattatc ctaagaagga aggtattata ttagttggga
    16081 ctatggaacc aaaaccagag gaaaaaccaa atacagacga aaataagaat aatcaaaata
    16141 caaacaatca aaatccaaat aatcaacaaa aaccagaaac accaccaact gataataagc
    16201 ctaatgagac acaaccacaa ccgcaagctt aaagttctca agaataggat ttatgtagag
    16261 taataaaaaa tataaatcta aataggaggg attactttga atttaaataa tataacgaat
    16321 tacgttcaaa gtatttgcga gaatatttct aatgtcttgg atgtagatgt tactttagtt
    16381 acaaaagatt taactaggat agcaggtaca ggaatattca gaggtaaaat aggagagaca
    16441 atatcagaga agtcagtgta ctctcttgtt ttaaaagatg gaaaatccta tgttataaat
    16501 aaagaaatag aagagaactg taataaatgt gcaaatagag aaaattgtaa agagttagct
    16561 gatatatgta ctcccgttaa aatgggagag catatacttg gaatcttggg tatagctgcg
    16621 tttaatgaag aacaaaaaga aaagatactt tcaaaagata aggagttaac tgcttttgta
    16681 aggagtatgt ctgatttaat atcttttaaa ctagatgaac tttataaaca agaagttaag
    16741 actatagatg accttgagag ggaagctata gaaaatgcca taaagaaata tggaagtaat
    16801 acagaaggta tgaaaaaagt agctgaggca ttaaatatag gtatagctac actctataga
    16861 aaagtaaaaa aattcaacat taaaagttaa tagtattgaa aaagaggtaa cctttttatg
    16921 aaaagaagag gattaccttt tttattatga gaatggtgga aaaatatgta tagttttgac
    16981 ttgacatatt aaatatgtta tcttaaatat atattttaga gtggaggtga gtattatttt
    17041 agttaaagat ataaaacaag acatagaaag catgcctaga aaaattttag atatatcttt
    17101 gatagaagat aataaaagtg atttgacttt ttttaatata gaagaagaag acggtgatga
    17161 aacattaaaa gcattaaaac agagttatgt gactacaaat tataaagaag aaactctatt
    17221 aaacttgcaa ggagctttaa attcaaagtc agatacaacg tctaaggagt taaaattaga
    17281 atcatataaa agatataaca atgcattgga tttagcatat aaaaattata taactagtgc
    17341 cattaatatg gttaataaag ctctggagat aaatcctaaa gacattgata tactaaatct
    17401 tagaggtctt ttaaaattat taaaatgtga ttttgctaaa tcatttgaga gtttttatac
    17461 tgctttatgt tatgagaata atcatatatc tagaaaatat gtaaatctaa tttcatctga
    17521 agattttaaa acttttttag gaagatacaa tcattctata agatttataa atgaagaatt
    17581 aaattatgag tcaatacata ttttagagaa cataattgaa gaagaacctg aactaataga
    17641 gccatatgta attttatctt tgttatatga taaactaggt aatgtaaaaa agagagaagg
    17701 atatttagac aaacttaaag agctagataa agataatcct gtatttgaaa aaaatgaaga
    17761 agaaaaagaa gatacaagta aaaaggaaga aataaaaaaa gtaaaaagaa agaaaagtat
    17821 tttgccatat attatagttg gctgtgtttt aataggtatg gggatatatt tgattcaaag
    17881 caaaaagaga atagaaaact tgaataacca aataagtagt aaagaggaaa agttaagtga
    17941 aactgataaa aagttaggag aaacgagtaa aaaattagaa aaaacgaata aggaattaaa
    18001 tgaggttaaa aataaagaac cagaaagaga gataactgta gctgatgagg aagatttata
    18061 ttatcaagct ctaaatttaa agaaaaacaa agaatatgaa aaagccatag ataattttaa
    18121 aagtgtagtt tcttctggta aaactaaaaa atatatttct gagtcaatat atcaattagc
    18181 aataacaaat aaattattag gaaataagga tgaagctata aaatattaca aaaaatatat
    18241 aaatacttat actaaaaatg accagtatta tgatgattca tattacgagt tgggtatgct
    18301 ttattatgat aatggcgatt taaaaaatgc acaacagact ttttatagtt tgagaagtga
    18361 agttccagac agtatgtata acaattcaaa aataaaagaa attttaagtg aaaaataggt
    18421 ttatatagtt aagttttttg aaacaaccaa gtatgtattt tattaaatta aaataaaaat
    18481 aaatttaaaa agagattgtg tcaaattata actttctatt ttaaagaaag atatttgctt
    18541 gttgataaaa ctacaaatat atgatttgaa gcaatctctt taatttttgg aggtggaaaa
    18601 tgaaagtttt caatcaatta gtaataattt tatctatctg ggtaatagga gagtatataa
    18661 gttcctttat acaaggaatt atacttattc ctgggagtat agttggtatg ctattattat
    18721 ttctactact acaatttaaa gttttagact tgagtagtat agaaaatgta agtggatttt
    18781 tcctcgataa tatggctata ttttttattc cagcaggtgt atcacttata aagtcattag
    18841 acctaataag ggaaaatgta ttagtgcttt tattagtcat atgtttaagt acactaatag
    18901 taatgtatac tactggaatt attgtggaga aaatgataaa aaagaaggaa gaaggacaaa
    18961 aaaatgtata atgtattaca gacaccagta tttggtataa tagtaacaat agtttttttc
    19021 aatttaggaa gatacattca acgaaaaaca agtaatccta tatgtaaccc tttattaatt
    19081 gcaatcgtag gaataatatt gtttttaagc atatctaaaa tcccttatga gaattacaag
    19141 ataggagctg atagtctaaa tttcttttta ggtcctgtca cagtagtact tgcagttcca
    19201 ctttataaac aatttgaatt atttaaaaag catatgtttg agattattgt aggaataggt
    19261 tgtggtatag tgatttcttt tgtatctgta ttgataattg gcaaaatagc taattcagat
    19321 gtaagtataa taaattcact aattccaaaa tctataacaa caccaatggg aatatcttta
    19381 gcaaattctt taaatggtat agaatcaata acagttgtag ccataatttt tacaggtatt
    19441 tttggtggta tggttgcttc tacagtattc aaactgggga atataaatca tccagttgct
    19501 aaaggaattg ctcttggaac atctgcacat gctttaggaa ctacaaaggc ttttgaactt
    19561 ggagaaatag aaggagctat gagtggtgtt tctattggag tttctggtac aattacagta
    19621 atactaattc caattataat gaattttata taaaaaataa aattaagatg agtaccttga
    19681 atacttaaaa caaaataaaa taaaaaaaat ttaaaataaa aactgaacga aaaaaatgca
    19741 aataatgaaa taaaaaaatc atgtactgaa attataaaaa gaaaaatttc atttaggaat
    19801 taattataaa gagacaatta ctaaacttga atttgctaaa ataaaataaa ttactgcgaa
    19861 aatagatatt tagaaaaaaa tactataaat ttactatatt gcaagttaaa taataagcag
    19921 tatcatatta tgctagaaaa agtttcattt aaggcataaa tgagatgatt tgaacgtttt
    19981 taaagattag aatataaaag attgcactag acatatatga aaaagataat ataatagatg
    20041 atgtaataga tgacagttca agaaattata aaaaaaattt atttgaaata ttatctatta
    20101 catcaggaat aatatatgta agagtaagct tttaaaattc taaagattta gaaagattga
    20161 agggagaaag aaatgagtga agttaagaat accctacaaa aacatccagt tttaagatat
    20221 tcaacaatgc tatttgggat gttgatgaca tctataggaa taaatgggtt cttaagacca
    20281 gcacatctac ttagtggagg tgctacaggt atagcaacat ctataaacta tttgacaaat
    20341 ataaatgtag gtttattaac atttttaatc aatattccaa tatttatctt agggttcata
    20401 taccttgaaa aagagttttg tatttcaagt ttggtaaata tgattgtatt ttcattatta
    20461 ttaggagcaa ctcaggaaat aagtaatatt atacctatac atgatatatt gcttcaaagt
    20521 gtatatggtg gtatattatc tggtttagga gtcggagttg tatttagaac taggtcttct
    20581 caaggtggta cagatataat agctgcaata ctaaaaatta agaagaatat agaaatgaaa
    20641 gacactgctt tagcaataaa tggcttgata gtacttacag gaagtttttt atttgggttg
    20701 gatttagcat tatacactct tataggtcta tttctaaatg cgtattcaat gagttttatt
    20761 aaagatgcaa tgaattacca aaaatctgtt atggtaatgt caaatgaagt cgatttaata
    20821 gcagaagata taatgaagag tttagttaga ggtgtaactt ttttagatgc agaaggtgca
    20881 tacactcatc aaaaaaagaa gattatatat acaatagttt catcaaatga gataccaaag
    20941 ataaaagata tagctttgaa gtatgataaa aaggccttta tatctgtaaa tgatgttaca
    21001 gaagtaaagg gaagagggtt taaagcaaaa gatttataga aaattttaca agctgggagt
    21061 ttataatgta aatttgtata ttatatctct cagcttattt aaatttagta tacgaaaata
    21121 aaggttttat taatgatttg tgtatcactt taaaagatat cattttaaaa ttaaaattga
    21181 aaaaattact taatatgtag aaaacatgac cactattagg atataataaa tttaatagat
    21241 ttagtaaaat atctaggaat aacgttggag gaatggcatt atgaatttat ctaaagaata
    21301 tgttaatttg tatgataatt atttgaaata tataaatgaa gtaaacaaag agattagaag
    21361 tataaagaac atgaagaaac gtgttttaaa aaggggcgat tttgctccag aaaatgaagt
    21421 attagaattg gaaggaaaaa caatacgtga tatagatgat gtcgatacaa aaaaaccaaa
    21481 aaataaaatc tataaatttt caaatgggga tgtatatgta gggaaattct tagagggaaa
    21541 aatggagggg aaaggctcat atactttttt tgtagatgaa ggaacagtta tggagtacat
    21601 aggagaattt aaagaagata aaaaaaatgg aaaaggaaac tttatatttt caaatggaaa
    21661 tgaatatata ggttattttg aggaagatat gatgagcggt attggaaata tgttatatag
    21721 tagtaaagat gaatatattg gaacttggaa aaacggaaaa aaagatggaa aaggtattta
    21781 taagtggagt gatggatgta tatatgcagg tgaatttaaa ggtggaaaga tggaagggta
    21841 cggtatttgc tataatagta aaggggaagt actttatgaa ggagaatgga agaataattt
    21901 gattcatggt aagggaactt atatatggga aaaaggtaaa aagtatatag gtgaatttat
    21961 gcatggtaaa aaacatgggc aaggaacttt ttatctaaat aatgaattgg tttatgaagg
    22021 gacttggaaa tttgataagc catctatatt tgatagaaca ttagatgaaa tattttcctt
    22081 gagactgtag ctttatctaa ttagtagata aagctttttt ctaatactta ctgtaaatag
    22141 gtatgaatga tattgattag tatacactat caatattaac ttaataaatg caatattaaa
    22201 aaattttgat tgattttaag aaggagagat atattgaaga gattaattgc tttagtgtta
    22261 gtagtactta ttgttttatt ttatagtcct gaattattaa aagaaggata tgatttaaaa
    22321 gaaaagtttt ttcaaagtga aatatggaat gaatttttag acaaaataaa tataaatgat
    22381 aattctaaga aagataaaaa agaaaaaagt caaaatttac aatcaaataa tactgaaggg
    22441 gagaacttag gagagtcaga tataaagaat tttgaaaaaa taagcttagg agataattta
    22501 agctatgttt tatcaagtat tggtaaacct ggtagaattg atattagtga atatggtttt
    22561 gattggtatg tatataatca atatggaaaa gaatttgcaa tggttggact tgaaaatgat
    22621 gaagtagtag cactttatag taattctatt aattcatgtg aaaatcaaga tataaaacta
    22681 aatcaagata gacaaacagt gagaactaag attacaccat taaaatataa gagaaaagga
    22741 aataccagat atataataaa ctcagaaaat caatatgata taataagtaa ggaaggtaag
    22801 tatattacaa ttttctacga tattcatgaa gaaaatagag tttgttcata cttaataatt
    22861 gataaaagca ctgaagatga gtttgaaaat ttatatccag atgatagcga agaacttaaa
    22921 aaatgttttg aacttgaagt tatagacctt gtaaatagtg ttagaaatca aagagggtta
    22981 aactcattga gatacagtga acaggcaact ttgagttcaa gaaaacatag tgaagatatg
    23041 agagataata atttttttga ccatgtaaat aagaagaatg aaactccatt tgacagaatg
    23101 aaaagagaag gtatagtata tacttcagct ggagaaaaca tagcagcagg acagattaat
    23161 gcaatatatg cgcatgaagc ttggatgaac tctgaaggac atagaaaaaa tattttgggg
    23221 aactataata atattggagt tggagtaata tttggaggaa gctataaaac atattacact
    23281 caaaattttt ataaataact aaaatatttg aaaggaagtt aaaaaatgac atcatggaaa
    23341 aaaaagacag tatataagtg cttaatagca gtagtcttgt tttgtggaat agtgttaata
    23401 tctaatttta gtaaagtttc tgctttgatg atggatacta atggaaatgt tttgattaaa
    23461 catggttcaa gggaaaaaaa gctaatagca attacctttg atgatggtcc tcatcctaaa
    23521 gaaactagtc aagttttaga tgtattaaag aaatacaatg taaaagctac tttttttata
    23581 gctggaaaac atgcaaaatg gtataaagaa ccattagtaa gagcaagtaa agaaggtcac
    23641 gagataggaa atcatacttt caatcatcct gatataagta atttaagttc tagtcagata
    23701 gaagaggaga ttgttaagtg tgaagacatt ttgaaagaag taactggaaa aaaaccgaca
    23761 ttatttagac caccatttgg aagttataga gaaaaagaat taatagaaat tgcaaaaaag
    23821 catgactata aagttgtttt atggacaggt gtagatgtga aagattggaa aaatccagga
    23881 gctaatagca ttgcagataa aataattaat aaagtacaaa atggagatat aatacttttg
    23941 catgattatg caactaatga tacagttgaa gctttagata tgtttattcc aaaaatgatt
    24001 gaaaaaggtt ttaaatttgt aacagtttct gagttgataa aataattttt aggggggaga
    24061 tttacagtat gattcttatg atagacaatt atgattcttt tgtatacaac ctagtccaat
    24121 atatagaaga attaggagaa acagttgtag taaaaagaaa taatgaaatc aaaataagtg
    24181 acattgaaga actaaatcca gaggtaattg tgttatctcc aggaccgtgt tctccaaaag
    24241 aagctggtat ttgcatagat attgttgagc attttaaggg gaaaaaacct atactaggaa
    24301 tttgtttagg tcaccaaact attggacatg tttttggagg agatattata aaagcacaac
    24361 agcctgtgca tggaaaagta tatagtatca accatactaa taaaggagtt tttaggggac
    24421 ttaaaaatcc tttaaatgtt actaggtatc attcactaat agttgactcc aatacagttc
    24481 caaaagaatt agaaattaca gcaattactg ataaagggga aataatgggg attaggcata
    24541 agaaatattt aatagaagga gtacagtttc atccagaagc tattttgtca gagtatggtc
    24601 atgaaatgct taaaaatttt ataacagaag ctagagaaag ggtacatatg taatatgata
    24661 agagagataa atactaaatt aaattctttt gagatattta ctatttttag aaatgaacat
    24721 gacagtttta tattagacag tgctatggat aaagaaaaat tgggaagata ttcttttata
    24781 agtagccaac catttaaggt attaaagtat aaagatactg atgaaaatcc tttagaagtt
    24841 ttaaaagaag aactacataa gtatagggtt gtaaatgata ctaatcttcc atttgtagga
    24901 ggtgctgtgg gatatttatc ttatgattta ggtaattaca tagagaattt acctagaact
    24961 gctgtagatg atattgagat gcctgatatg tattttggat tttataatca tgtaatagtt
    25021 atagaccatc ttgtgcaaaa aacttatata gctactccaa acatagatat cgaattagaa
    25081 gaaaagataa tagatgatat agaacaaaga atattaaaag aagagaaaaa aggtatagat
    25141 agcatatgtt atgaagaaaa agaagtaaca cctataagac ttaaatctaa ttttacaaag
    25201 gaagaattta aaaatgcagt tcaaagtgtt agagagtaca taagacaagg agatatatat
    25261 caagctaatt taacacaaag gttcagtgga gaaacagaac ttacaagctt tgaattgtat
    25321 agggacttaa gaagatttag cccagcacca tttggggcat tcttaaactt tgaagatgca
    25381 catatattat caaattctcc agaaagattt ataagatgtg ttaataagag aatagaaact
    25441 agaccaataa aaggtactcg tccaagaggg aaagataaag aagaagattt aagacttcaa
    25501 caagaactta gaaatagtga aaaagataga gctgaactac ttatgatagt agatttagaa
    25561 agaaatgata ttgggagaat atctaaaact ggaagtgtta aagttccaga gctatttgta
    25621 attgaaccat atgcaaatgt aaatcactta gtttccacag ttgtaggtga gttaaaagat
    25681 gataaagatg ctactgatgt aataaaagca acttttccag gggggtctat aacaggagca
    25741 cctaagatta gagcaatgga aattatagac gaattagagc caacgcaaag aaatgtatat
    25801 actggttcaa taggttatat aggttttaat ggtgatatgg attttaatat agcaattaga
    25861 acaataatca aaaatgacaa aaaagtctac tttcaagttg gaggaggaat gacttgggat
    25921 tctgacccag atgaagaata tcaagaaaca cttgataaag ctaaatccat aatgaaggct
    25981 ttgaggggat attatgaaga ataatgtagg ttttgatagt agtttaagta aatttggaat
    26041 tggtttgttt gaaactatta gagttaaaaa tggaatagca gtagatttag atatccatat
    26101 agaaagaatg ctaagctcaa taaattgttt ggatttagat ataaactata aaaaagattt
    26161 cttgataaat gaaattgtta catatataaa aaaagaaaat gtcattaata aagcacttag
    26221 aattactgtt tttgatgaag gttataatat atctattagg gatattccat ataatcaaga
    26281 gacgtatgag aaggggttta aattagctat atctccaata gttaggggga atagtttaat
    26341 tcatagacat aagactacta attattttga aaacatatat accaaaaata tcgcaaataa
    26401 gactggttat aatgatggta tatttttaaa ttcagaaggt gtaatattag aatgttctat
    26461 gagcaatatt ttctttataa aaggagaaag agtgtacact cctagtgata gattaccgat
    26521 attaaatgga ataataaaaa aaaggattat agagatttgt gacgaattac atatagagtt
    26581 gatagaaaat gaaattaata tatcagaaat tagtagtttt gattttgttt ttgtcacaaa
    26641 tagtcttatg ggcgctataa aggttacaga aattgacaaa ataaaattta ataaagaaaa
    26701 tgttgttttt gataaaatag tgaagttatt agaataaatt aaaatattaa caatttgttg
    26761 gagacaaaag atgataggtt gtatttatga agtatacaat gaagagatga ctaaaataat
    26821 agaaaaccaa aacactttgg ctgtatattt agtgggttct agtaaagatg tagattttac
    26881 tctttatgat gtagtgataa acgatattga tgtgttcgtt tttgtaaaag aaggggaaaa
    26941 acaagagaga atactgttta aaaaaaaggg aatagaattt gatgtaaatt acttttcaaa
    27001 agatggtgta aaaaaattat tatcaaatag ggaatatttc tttgtgaaag aaatgaaaga
    27061 tgctaaagta ctgtttgata gggagaatat atcacatatt ataaaagata taagtagaga
    27121 tatttactta gaaggaccta gtaaaatgtc attagaggaa aagtctttta taaagcaaga
    27181 tattggagca aaaatatcga atttaaaaaa taaagaaaaa tttgatgttt ttgaatatca
    27241 ttttttgacg aatttatatt taaaagatat aataattggg tactttaata taaatgataa
    27301 atgggtacca aaagacaaaa aattgctaaa agttttaaaa aaagaaaata atgagctttt
    27361 tgaactagtg tcaaaagtaa gtgaaaatta tgactatcaa agacttttag atgtttataa
    27421 ttatattttt aaagaaattg agacaaaaga ggttataaaa ctaatcttct agtcacaaat
    27481 caatgggggg agtttaaatg aataaagttg ataaagaaaa gatacaacat gcagtaagag
    27541 aaatactaga ggcaattggg gaagacccag atagagaagg tctaatcgaa actccaaata
    27601 gagttgctag gatgtatgaa gagatattct ctggtcttag tgaagaacca agagaccatt
    27661 taaaagttct ttttgcagat gaaaaacatg aagagttagt attggtaaaa gatattccat
    27721 tttattcatg ttgtgagcat catctagttc ctttctttgg aaaagctcat attgcttatt
    27781 taccaaaagg aggaagactt acagggcttt ctaaacttgc tagagtaata gatacattgg
    27841 caaaaagacc acaattacaa gaaagaatca ctaaaaatgc tgcagatata ataatggaag
    27901 aattacaacc ttatggtgtc ttagtagtag tagaagctga acatatgtgc atgacaatga
    27961 gaggcgtaaa aaaaccaggt tcaaaaactg ttacatcagc agtgagagga atatttgaaa
    28021 aggacattgc gtctagagcc gaggctatga gtttgattac tatgaagtag caatttatta
    28081 tagatataat catttattga gataaaattt aatttaaggg agtgtcatta attgtgtttg
    28141 attatggtaa aagaacttat ataatgggaa tattaaatgt aactccagat agtttttctg
    28201 atggaggaga ttttaataac ttggacatag caatacaaca tgcaaaagat atggttgacc
    28261 aaggtgcaga tataatagac ctaggaggag agtctacacg cccaggtcat agctatgtag
    28321 actcagacga agagctaaga agagtaatcc ctgtaataaa aaaacttaaa caggaattgg
    28381 atataccaat atcaatagac acttataagg cagatgttgc agaagaagca ttaaaattag
    28441 gtgtcactat ggtaaatgat gtttggggtc ttagaaaaga taaaaatatg gcttctgtaa
    28501 taggaaaata tgatgcagaa gtgtgtataa tgcataatca agatgggaca aactatgaca
    28561 aagatataat ggagtcaata aaagactttt ttaaggtaag tatagaaatg gcaatgagtt
    28621 gtggtgtaaa aaaagaaaaa atagtacttg acccaggtgt aggatttggc aaggattttg
    28681 aacaaaatat tgaagtattg agaagattaa atgaattaaa agatttaggg tatcctattt
    28741 tgcttgggac atccagaaaa tcagtaatag gaaaagtact tccagttgag cctaaaaaaa
    28801 gattagaagg tacaatagct actactgttc ttggtataag agatggcgta gatatagtta
    28861 gagtacatga tgtttatgaa aatttaatgg cagctagaat gactgatgca atatatagaa
    28921 agtaggtata atataatgga taaaatatta cttagtaatc taggattcta tggatatcat
    28981 ggtgttctta aagaagaaaa ttttctaggt cagaaattct ttgtcgacat ggaactttat
    29041 attgattcaa gagaagcagg tcttagtgac gatataaata aatctgtaag ctatgccgag
    29101 gtttacaatg ttgttaaaga tattactgaa aataaacaat ttaatctttt ggaggcttta
    29161 gcggaaaata ttgctgaaga agtcttgaat aaatttatac ttataaatgg agttatggtc
    29221 agagttagaa agcctgaggc tcctgtaaat ggtatttatg actattttgg tgttgagata
    29281 aggagaacaa gagatgaata aggcttattt gggaataggt actaacatgg gtgatagatt
    29341 tgataattta tcaagagcat gtgaactttt gaaaaatagt gattctatat ataaagtaaa
    29401 agaatcaagc ttatacgaaa caaaaccatg gggatataca gaacaagcag attttctaaa
    29461 tatgtgtgta gaaatagaaa cagagtttga accttatgag ttgttagaat attgtcaaga
    29521 aatagagaga gaactacaca gagagagaat agttcattgg ggaccaagaa ctatagatgt
    29581 agacgtacta ttttttaatg atgtagtttc cactgatgaa agactaacaa tacctcatcc
    29641 aaggattcaa gatagagctt tcgttttgat accacttatg gatttaaatg aaaaacttat
    29701 aataaatgaa aaaacaataa aagaacattt aaacctccta tctgctgaag aaagagaaga
    29761 agtaaaggag cttgtaggtt atgaaagaaa acctatttaa taataattca aagatagaga
    29821 taaatacaaa taacaaaaag ataactgtaa aaaaagataa acttataata gctggaccat
    29881 gcgcaataga gagttatgag caacttttgg agactgctaa atttgtaaaa agtcagggag
    29941 caaacatttt aagaggtgga gcatacaagc caagaacatc gccaaattca tttcaaggat
    30001 taaaaaaaga aggtcttgaa atattaaaag cggttaaaga cgaagttggt atggctgtta
    30061 ttacagaact tatggatgta agagatatgg acgaactgta tagtataagt gatataattc
    30121 aaattgggtc aagaaatatg caaaacttta ctcttttaag tgaagtggga aaacaaaata
    30181 aacctgttat gttaaaaaga ggaatagcat ccacaattac tgaatggata ggtgcttctg
    30241 aatatatagc aatagaagga aatagtaata ttataatgtg tgagagaggt ataagaacgt
    30301 ataatgatta tactagaaat acattagatt tagctgcggt acccattatt caaaaggaaa
    30361 caggtcttcc tgttgtggta gacccaagcc atgccactgg agttagatat ttggtaaaac
    30421 ctatgtcact ggcatctttt gcatgtggag cagatggaat aatggtagaa gtacatcctg
    30481 acccagaaaa tgctttgtca gatggtgctc aatctctttg ctttaatgaa tttgaagatt
    30541 taatgaaatc aattaataat tattaaaaga ggcaagagcc tcttttttat tcgtaatcgt
    30601 tgctaaggta aatttataag ttataatttg atagttagat tatttaatat aaataaagat
    30661 ttaatattga tagaattaat ataaaaaata aaaatttttt gattaataag aaggatatca
    30721 ataaaaaaag tcgaattgtg tatattgagt gattgacaaa tttagaatat agtgtagaat
    30781 agaaatgtta acacaaaaaa ttacaccaga aggtgataat atgaatgata taaaagacat
    30841 tattgaagaa ataaaagcta gatgcgatat agcaagtata atatctgaat atatgaatat
    30901 aaaacaatct ggagctaatt acaaaggatt atgtccattt catggcgaaa agacaccttc
    30961 tttttatata aatacatcaa aacagattta taagtgtttt ggttgtggtg aaggtggaga
    31021 cgtaataaat tttgtcatga aaatggaaaa tttggatttt atggatgctg taaaaatttt
    31081 agcaaataaa tgcggtatag aaattaacac taacatgaat gaagaaacta ggattaaaat
    31141 agaaaaatct aagaaatttc aagatattca tacggaagca gctagatttt atctttcaaa
    31201 cttattggga agcaaaaatc ttgggtatga atatttaaga ataagaggac tagatgataa
    31261 aattattaag aaatttggtt taggattttc tttggattca tggaattcac ttatgaatac
    31321 tctaatcagt aaaggatata aaaaacaaga cttattggag tgcggtctaa ttgcaaaaaa
    31381 tagagatgga actaattgct atgataaatt tagaaataga gttatgtttc ctatattcga
    31441 ttatagagga aatataatag gatttggggg aagagtatta gacgattctt tgccaaaata
    31501 cttaaattct ccagacacgt taatttttaa taaaaaacag aacttatacg gattaaattt
    31561 tgctagaaaa aatttagaaa gtaaaactat agtcttagtt gaaggatata tggatttaat
    31621 ttcgctttat cagtatggta taaaaaatgt agtagcaacc cttggaacag ccttgactga
    31681 acaacaaggt attttaataa agagatatgc ggacactgct attatatctt atgattctga
    31741 tgaagcagga ataaaagcga ctttaagagc tatagatata cttactaaat taggtatcaa
    31801 tgtaaaagtg ttagacttaa aagatgctaa agacccagat gaatttgtaa gaaaatacgg
    31861 acttagtgat tataaaaaag ctatggatgt ttctactcac tacataaaat ataaaataga
    31921 tcatcttaaa aaagaattta acattcaaaa agatgaagaa cgagtgaagt tcgcaaaaga
    31981 agcttctaaa attataaaac aattgacaag tcctgttgaa attgattttt atacaaagta
    32041 tttaagcaat caaatagata ttaatgtcga gtctataaag agagaagttt atggtaaaaa
    32101 ttacaataag ccatataata acaaaaatca aaagaaaata gaagaaaaag taattgaaaa
    32161 agtggaagtc agacaagacg gaaaacaatt agttgaagaa actctaataa aaataatgtt
    32221 agaagacaaa aaaattagag aaatagcgtt acttaaagta gaagaaagtg attttttatt
    32281 gaaagaaagt aaagaaattt taaattacat gattaaaaat caagaattgg acaaaataac
    32341 tattgacaaa ttgaaaagtt taaacatatc cgaagaatac ttaaaagaat taaattcaat
    32401 ttctttgaat agtataaact tagagaacac aaaagaaata gaaggaataa taacaaatat
    32461 cagaaaaaac tcattagaag agcaaattaa tagcttgttg agagaacaac aagaattaga
    32521 aaataataat gatatgaaag aggtagatgg tagagttatg gaaattgctt taaaaatagt
    32581 tgagataaat aaaattttaa agagcttgta gagaaaggag gtttgagtgt ggaaaataaa
    32641 tcgaataaaa aagagttaaa aaaggttact gctaagacat taatagaaaa aggaaaaaag
    32701 caaggttctc tgacacttgc agagataatg gaagcttttt cggagactga acttgataag
    32761 gatcaagtag aaaatcttta tgagacttta ggaaatttgg gaatagaaat aacagaaaca
    32821 aaaaactata aagctgatat agatttttcg gttgctgatg acgatttaag tataggccac
    32881 ttagatgaag atgcagaggc aatttcacat gatgactctt ctgcaataga aatagaaact
    32941 gtggatttat ctttaccaaa agggataagt atagatgacc ctgtaagaat gtacttaaaa
    33001 gaaataggaa aaattcctct acttaaacca catgaagaag tagaatttgc tagaaggatg
    33061 cacgaaggtg atgagatagc aaaacaaagg ttagttgaag caaacttaag actagttgta
    33121 agtatagcaa aaagatatgt aggaagaggt atgcttttct tggatttaat acaagaggga
    33181 aatttaggtc ttataaaagc agtcgaaaaa tttgactata caaaaggata taagtttagt
    33241 acttatgcaa catggtggat aagacaagct ataacacgtg ctattgcaga ccaagctaga
    33301 actataagaa taccagttca tatggtagag actataaata agctaataag agtatcaaga
    33361 caactacttc aagaacttgg aagagatcca aaaccagaag aaattgcaaa agaaatggaa
    33421 atgacagaag ataaagtaag agaaataatg aaaatagctc aagaccctgt gtctttagaa
    33481 acaccaatag gagaagaaga agatagccat ttaggtgact ttattccaga tgatgatgct
    33541 ccagccccag cagaggcagc agcatattct ttattaaaag aacaaataga agatgtactt
    33601 ggttcattaa atgatagaga acaaaaagta ttaaagctta gatttggtct tgaggatggt
    33661 agagccagaa ctcttgagga agttggaaaa gagtttgatg taactagaga gagaataaga
    33721 cagatagaag caaaagcact aagaaaacta agacatccaa gtagatcaaa aaaacttaga
    33781 gattatttag actaaaaaga tacatcattg atgtttttgt gataaatgcc atgagataag
    33841 tgatatctca tggctatttt gtagtaaaga tttaatttta tttttgtagt tatttcagtc
    33901 taatatctat aacttggatt aaatcctata aataaaggga attgaaagga gaattatatt
    33961 tgaaattaac agatagatta ttgaaaatag catcattagt gtcagatggt aaaaaaatag
    34021 ctgatatagg gacggatcac ggatacatac cagtatattt gttaaaagag ggaaaagtac
    34081 catttgcagt gttagcggat gttaataaag gacctcttga caatgcacat aaagaagtca
    34141 tacagaacaa tcttttagat aaagttgatt tacgattggg ttctggtata gagatacttg
    34201 aaatagggga agtagaagaa gtgataattg ctggtatggg tggaatcttg ataagtgagc
    34261 ttctcgaagc taaaaaagaa gtagcacata atgtagaaaa attaatatta cagccaatgc
    34321 aagcacaaga agaacttaga tattaccttt taaacaacgg atatgaaatt ttagaagaag
    34381 ttttagtgag agaagatttt agaatatatg agataattgt tgccaaatat acaggtaaaa
    34441 atactataat agaagatgag atatattatg aggttggaat aaagctttta gaaaacaaag
    34501 attctctttt taatgatttt atagaaaaaa agataaagac atatagttct atagttaata
    34561 aattagaagg gaaaaatggg gaagctatag ataagaagag aaaggaaagc gaagttgcaa
    34621 taaaaaaact tgaaaattta ataaaataaa taggaggtat atatgctatt aaagagtcta
    34681 actagaaaaa ttgaaaaaaa gtatcctcta aacttagcag aggattggga taatgtaggt
    34741 cttatagttg gagattttga tatggatgta aaaaaggtat tggtatcttt agaagctaat
    34801 gaagatgtta ttgatgaagc tatatccaaa aatatagatt taattgtgac acatcatcct
    34861 tttatatttg ggaaaattaa taaaattaat agtggagatt taaaaggcag acttatccaa
    34921 aaacttatta aaaatgatat atcactttat tctatgcata cgaattttga tatagcattt
    34981 gatggtctaa atgactattt tatggaaatt atggaatttg gtaattcaaa ggttttagat
    35041 ataactaaaa gcgaaaattt gtataaatta gcagtatacg ttccacataa ctattcagat
    35101 gaacttagaa aggttttaag taattcagga gcaggtcata tagggaatta tagtgattgt
    35161 acgttttcaa tagaaggtga aggacaattt aagccattag aaggctctaa tccgtttctt
    35221 ggaagtgtaa atgatataga aactgtaaat gaagttaaaa ttgaaactgt agtaccacag
    35281 aagcttttag gtggggtaat aagttctatg ttagatgcac atccttatga agaagttgca
    35341 tatgatttgt acaagttaga aaataaaggt gagatatttg gactaggtag aataagtaaa
    35401 cttgataaaa gtatgacatt agaaagtctt tcaaggaaaa taaaagagaa attaaatatg
    35461 aaacacataa gagtagttgg aaaccttagt acagacataa cgaaagtagc cgttgtaaca
    35521 ggagctggtt cagaatttgt aaaaaaagct aagagacaag gtgcagaagt actaattacg
    35581 ggtgatgtaa agtatcatga ggcacaagat gcacttgata ttggaatgtg tatagtggat
    35641 tgtggtcatt ttgatacaga agatatattc aaaaatgtta tgaagagatt tttagatgaa
    35701 tttagtgaaa ttgaagtaat aaagagtaat gtatatttga atccatttag tactatttag
    35761 cagtgtttga taataaaaat actatataaa aaataaattt gagtttaatt agggggataa
    35821 tgatgaaagt agcagtaatt tttcatagtg tttgtgggag tacatattta ttagctagag
    35881 aatataaaga agcgcttgaa gaaatgaata tcgaggtaga tatatttaga gtaagtgacg
    35941 aagttgcaaa aacacttcct caatattatt tgataaattc caaagaatac aaagacgaat
    36001 ttgaaagtat aaatgtaatt aaatctggaa aagaaatatt agattatgat gctatattta
    36061 tgggttcacc aacatattat ggaaatgtat ctggaccaat gaagatgttt atggatagtt
    36121 tttctgatat ttgggtaggt gctcctttga gtggtaaaat atttggttgt tttgctacag
    36181 caggttcaca acatggagga ggagaattag ctttgcaagc tatgaatata tttgcccaac
    36241 atatgggaat gactcttttg tcagttccat gttcagtaag aggaggttat ccagcgtatg
    36301 gaatacttca tatagcagga gataattctg atataagacc aaatgatgat gccaagatag
    36361 gtataagaga ttacctaaaa agacttaaca tataagaata tcatataaaa atacctaaaa
    36421 gcgactgtat atacttttag gtatttttac ttaattataa acgtgaagct ttaccagaaa
    36481 tatggtcaat ttctatttta acaacagttg ttaagttcat atccttctct atgtacttca
    36541 tgccttcttc aaagaatcct ttagaatatt tttttattat ttctacaaga gcatttttct
    36601 tttcttcatt ttctacagtg caagcttttc caaaaactat agcactagaa taagtagtac
    36661 taaatttatc tggaataaca ctttcattag caactactaa aaaagaaact ttgttgtttt
    36721 tcgatatatt atctaactta tgcccatttc ttgcacaatg aaagtaaata gaatcattaa
    36781 agtatacata atttacagca actccataag gataaccatt ttcagatata gtggaaaaag
    36841 taccaaattc accatttttt aatacttcaa cagtatcttc ttttgtcatt tctctttttt
    36901 tcaatctcat ttctttaaac ataatatcat cctttctaat tttgatgctt aaattaaatt
    36961 ttagaacatt tataaagatt atgctatgtt ttttacaaat tttaagaaaa aaatatagtt
    37021 taagataaaa ggtagtgaaa gagaagctat ttggaggttt atttatgata ttattgttag
    37081 agtagtacaa ataatactaa taaatttaat agctggtttc ttgttattta aggtagtaag
    37141 catgtctata agaaggggaa gttatcgagg gtagaagttg ttgtttataa tgatattata
    37201 aagaaaatat tattatataa aataataaat agtaaagagg tatcaagttg aatataatac
    37261 ttaatacctc ttcaaaatta agttataaaa gtgttgtggg aattgtccta tacatggtaa
    37321 ggagataata aagaatgtat ctttaaagtc tcaactaaac agcaaaattt atccaacaaa
    37381 catacaataa atgcttcttt gtatctaggt ggcttaacag taagtggcca catgtgtttt
    37441 aaaattatgt ccgtttcttt ttcatttatt tgaaaaaata aagttgcatt ttttaatgct
    37501 tctctagggt gagtaaatcc atgtaatcct tttctatcac ctttgtaatg ccaatcataa
    37561 agaaaaaagt cgtgtagtaa agctcctcta ataacacttt gaatatcaac acttaagtgc
    37621 aattttttac ataatagata actataatat gctactgaca aactatgttc aagacatgaa
    37681 acattgccat gatgaggaaa tgttctcata agttgaactt tttcagaaga aagtatctca
    37741 gaagcacatt cattaaaata tttgatttca gcttttgaca acattatgaa aatctccatt
    37801 cttagtaata tataaatact atacttcaac gataatatga aatatttctt atcctacaaa
    37861 atataatacc caataataca agtaagatac cttttatggt attttaaagt aagagagatt
    37921 ttattaggct aaacaatgaa aaaattaaaa gtaaagctat agcaatatat agtatttttc
    37981 caagaggatt gccaaaattt atagtccatc caataccaaa ccttttatta accattaatg
    38041 atgggtcatt tggattatta tacatgatgc ctgctatcca atacttctca tcttcttctg
    38101 gagaataaga tgagttgaat tttaaatttg gggaattaat atatgttgct attaaataaa
    38161 ttataattaa aagcgttgta atattcatag cagttgatag ttttgttttt attgataaaa
    38221 gagtagtaaa aaactgtgtt gtcattataa tcatcaatat taaaaacaaa taaccaattt
    38281 tatttaaata tttaatgttt tcaactctac tttcttcaat tctatttgta tctatcttaa
    38341 tccttgactt tatggatcca atggaagtta tatataataa aaccattaaa caaaagtcag
    38401 taccgattaa tttaaataca ttaagaaatg atttatctat aaaaacatca ggagacccat
    38461 ttatgttcca atgagtggca attgagtctg gcaattgatt ataattaaat gctataaaaa
    38521 tactcattcc caaagtaaat agtatcggta ttaaatagat tattttaaat ttttttatta
    38581 ttttattttt cttatttata aaatccatat ctactattaa ttttgaatct atatctatat
    38641 gacctaattt agaataaatt tctgatttaa gcttcttagc ttttttatgt gtatgaatat
    38701 atagtatact ttcatatatt aaaaaaccta taataccaat aaaataggaa agttccaatt
    38761 tattaaatgt aaagaccaga ataaaaacta atataaagtc tataataaaa cctaaagata
    38821 atagtttttt aaattcttta tctaacttta taaagtaatt ataattttta tgctcttggt
    38881 ctatagaaac tccatagatg tgttttttac ctacaaaata gggcataaaa taaaatgtag
    38941 catacatcaa aattagaact ggaaatattg taaatagaca ttcaatctta ctcataatat
    39001 ttcacctcat acttgtcaaa taaacttgaa cttagtgaca aaaattcttc tttactaata
    39061 cctgataaat aagattttgc caccaataat tccaagtcaa gtttattttt ttgacgagtt
    39121 gtattatcta ttttcattgg tagttgagct acaatagcac cttttcttct atcaatattt
    39181 aagaatccct cttcttttaa ttcattgtag gatttgttca ctgtatgtaa atttacacca
    39241 atattttcag ccatacttct tacagatgga agtgattcat ttattttcaa ttctcctgaa
    39301 gctatagcct tagttatttc ttctttaatt tgtacataaa tagatttatc actattaaaa
    39361 tctaaattta aaaccataaa aaacctccat tatgctttat aaatgaaaac gattgttata
    39421 tacatagtat aacataaaaa ataataacaa acacaaaata taagtttata ttttgtaaaa
    39481 attgtaattt aaaaaataac ataattttta ttaaaataat acagatacta tttatagata
    39541 gaaataaaaa ttagaaagga gaaaaaatat gttaacatat ttaatgaaaa gacaaatgca
    39601 taaaaaagat gatggaatga gtaaaccaat gatgattaca ggagctgtaa ttacaggtgt
    39661 aggagcatat gctgtatata aaatggtaaa aagccataaa tctaattctc aaatggtcaa
    39721 tacaaattat tatggaaata gcgattatga tgattataaa tatgacgaat ttgattatga
    39781 ctgtgattgt agagacacaa aacaagatta tgaatatgaa gaattaaaaa aaaaagtaaa
    39841 agaatttaat tcaagaagaa taaattgtga aaattgtcca catgtttctc aagaagaaat
    39901 gatgcaatat gtaaatagtg ttaaagatgt aaaggaagag attgatttac atgaagatgc
    39961 taaaaaagat aatatttaca aagaagatga atacaaaaaa tatgaagaag aataagtaat
    40021 attttgtata actgaacaaa tagtaatgtc aaattattta atatctagtt ttaatatgta
    40081 agttgtaact taacttgaaa gaatcagtat cattctttag atagttaagt aacaacttac
    40141 attttatttt tataaatttt aatagttctt tgtgactatt ttgtaatttt agaaatattt
    40201 tagtatccag ggtaattgtg tataataaaa cttgtataga tagatagtat gaaattaagc
    40261 agatagttta aaattaaaat gaaaagaaag gaaatagtta tgttaaagtt gttgatagtt
    40321 gaagatgata gtactatatc ttttggaata aagtatgctt tagaacaaga aggatttagt
    40381 atagatatat caaaggattt atctagtgga aaagaaatga tttcttctaa tgaatatagc
    40441 atgatactgt tggatgttac attgccagat ggaactggtt atgagctttg tcaatatata
    40501 agaggattct ctcaggttcc tataatattc ttgactgctt gtgatgaaga agtaaatatt
    40561 gtaatgggtc tcgatatagg tggagatgat tatataacaa aaccttttag aattagagaa
    40621 ttaatatcca gaataaaagc tgttttaaga agaaaaggta atacttcaga agaaaataag
    40681 aaaatactta aatttggaga tttaagtata tatacattag aagctagagt atataaaaat
    40741 gataaagaaa tatttctgac atcagttgaa tataaacttc ttttaattct tatacagaat
    40801 aaaaatactg ttttaagtag aactcaaata ttggaaaaac tttgggatgt aacttatgat
    40861 tttgtaaacg acaatactct aactgtttat ataaaaaggc ttagagaaaa aataggtgat
    40921 gatttatgtg aaccaatcta catagaaact gtaaggggga ttggttataa atggatagga
    40981 agtgaaaata gtgtttctat ataatccaga agtgaagaag tttttaagta agtatgttac
    41041 tttgatgttt attgttatca taatatctat tggatttagt ataatcaacg tatctttaac
    41101 taaagagatg gttgtaagaa ataatcaagc tataataggg actttatcgg gtaagtatcc
    41161 aaacttagaa agtgatatag tagatataat aactcaaggg aagtctatgg agaacataga
    41221 ttatggtcag aaaatattaa gtaagtataa ttatgataaa tctattaaga taaactctga
    41281 gcctattatt tctaaattag ttttagagac tatcaaaata aatataatat tagtatgtat
    41341 aatatttatt ttgatatttg tgttggttgt tagatatttt acgtcaattt acaatgattt
    41401 atcagatatg actaagtatg tttactatag ttcagagggt aagccatttg atataaaaaa
    41461 caagaatcaa gaagggcaga taggtcttct aaaaactgaa ctcttaaaga tgacgacaat
    41521 tcttaatgaa aaggttgaac ttttaaaaag agaaaagata tttttaaaca atacaatttc
    41581 cgatatatca catcaattaa aaactcctat gacttcttta ataatgttga atgatttatt
    41641 atataatgat gtaccatacg aagtaaaaat cgatttttta aataagataa aaaatcaatt
    41701 aaatagaatg gattggttga ttaaaagcat gcttaaatta tcaaaggtag aagcaaaagt
    41761 gataaatttt aaaaaagata aggtaaaatt tagtgaactc atacatagag caatgctatc
    41821 tatgaaaata cctatggaga ttaaaaatca aaaactgact atagagggaa atgataatgt
    41881 atcttatatt ggtgatattg attggtccgt ggaagcatta gtgaatataa tcaaaaattg
    41941 tgtagaacat actcctgaat ttggaaatat aattataacc tataaagaaa atccattatt
    42001 ttctgaacta ataataaaag atgagggtga aggtatagat aaaaaagata taccacatgt
    42061 atttaaacga ttctatagag gaagaagtag ttcaaaagaa gatagtgtag gaataggtct
    42121 tgcaatgtca aaatctataa tagaaagcca aaatggcgat atatatgtaa acagcgaaaa
    42181 aggtaagggt acagaatttc atataatatt tcataaaatg tatgatagtg actaatctgt
    42241 aatatttaat tcactttata gtaatagcca aaacctaata tatgaagtat agaatataaa
    42301 tattggaggt agttatggaa attttaagag tagaaaatat aactaaaagt tatggtaaaa
    42361 atgaaacaaa agttgatgct ataaaaaatg taagtttatc agttgaaaaa ggaacgttta
    42421 tagcaataac aggtccaagt ggaagtggta aaagtacctt attacattta ttaggaggag
    42481 ttgacagacc aactagtggt aaggtttata taaatgatgt tgatatctat aatttaaaaa
    42541 ctaaggattt ggcgatattt agaagaagaa atataggtct tatatatcaa ttttacaact
    42601 taattccagt cttaaatgtg aaggaaaata tattgcttcc agcagagctt gacaatagag
    42661 atattgatag agaatatttt gatgatttaa tgaaaacatt aggtctaatt gatagagaaa
    42721 agcaccttcc aaaccaatta tcaggaggtc aacaacagag gacctctata ggacgtgcat
    42781 taattaatag accttctata atattagcag atgagccaac aggtaattta gatagtaaaa
    42841 attcaaagga aatattagaa ttgttaaaat tgtcagtaaa aaaatacaac cagacactaa
    42901 taatgataac tcatgacaaa aatatggcac ttcaagctga tagaattata agcatagaag
    42961 atggaatcat aaaaagtgat gaggtgatgt agatgaattt atatacatca ctaactatta
    43021 gatacttaaa acaaaataaa agaagaacca ttgtaaccat aatcggtata atactttcaa
    43081 cagctttaat ttgtggtata ggaaatatat ttgaaagttt tatggattat caaatgagag
    43141 aaactataaa gaatgatgga agtttccatg ttacatttta tgatgtaaat agaagaaatg
    43201 tggaatatgt aacgaaatca gctgaaatag aaaaacatgc atttaccaaa caacttggat
    43261 attctaaatt agaaaatagt gaaaatgcta tattaagtat aaagcaatat gataaaaatg
    43321 caataaacgg atataaagtt tctataaaag aaggtagatt tccagctaag gaaggagaaa
    43381 ttgttttaag tgaaagtatt attaatctta tagatgataa gttaaaaata ggagataaga
    43441 taactttaaa agtaggggat atgtttgact caagcaagaa aaagattgat agtatgacat
    43501 ttcatgaagg tgattatata gcaaatgaaa aagatagaac ttttaaagtt gttggtataa
    43561 ttaaaaaacc tgggtttgaa cgttataatg gaattgcaac agctatagcc tactttaatc
    43621 ctatgaataa ttacaatgat acaattaatg tatcagtagc agtaagaaat cctaaagatg
    43681 tgtataagat aagtaataaa ataagtaaaa atatatattc aaataaagat aaagaagcag
    43741 tttctgatat gataaaatac aatgaacatt tattgaggtt acaaggtgct agtaagtatt
    43801 caaatataaa tagctctata aagtctataa ttatagcagt aactatttta gtaatcatat
    43861 gtacaattgc tacagtgtac aattccttta gtatttctat aaatgaacga aaaaaacagt
    43921 ttgggatatt aaattctata ggtgctacat ctagtcaaat taaaagatta gtttttatag
    43981 aaggtattat aattagttta attggtatac caataggact aatatctgga acagtagcta
    44041 tagacttatt gtttaaaatt ataaataagt attttactga atcggttgtt actaagatga
    44101 gtttgcagat agtgtataat ccaataataa ttattgttag tataataata gttttgttta
    44161 caatctttat atcaattcta ctacctgcaa tatcggcttc taatatttct ccccttaatg
    44221 tgattaaaaa tactggagag tataaagtgg gcaaaatcaa aagctcaaga cttattaaaa
    44281 tgatttttaa aactgaagga gtacttgcat ataaaaatat taggagaaat agaaaaaaat
    44341 ttataataac tcttttttct ttaatggtaa gtataataat atttatatct tttagtggct
    44401 ttacattact tttactaaga ggtgaagaaa ttagaaattc tcaaagaaaa tatgatttgt
    44461 atttaactgc aaagaacaca gctaggtctg tagaggatac tataagtgaa ctagaagata
    44521 ttgatgggat aaaaaacttt gaattggcaa caggacaata tgtgtctata agagtaagtg
    44581 aaaataaaat aaataaatcc aaggaagatt taatcaggaa atattatcaa aaatataaga
    44641 ttggagatag ttatgaatat gatttcagta ataatgaagt aatttttcca ggagattttg
    44701 cagtaaaaaa caaaataaat aacttagtac agggctcttt taataaagag agagcaattg
    44761 aagaaaatgg tgttatatta gttagaaaaa gtgcatttga agaaaatggg aagaaaggtg
    44821 tagtagaact taccaactat aaagtaggag atacagtaaa ttgtgaatat cttgatgaaa
    44881 atgccttaag taaaaaagta aaggtcaaga ttcttgctat aactgatgaa gaacgtctag
    44941 gtcttggtta tcaaaatatg gggttacaat ttataactta tgatgaagtt gctaaaaatt
    45001 taaatttaaa attaagtaaa agccttatat ttattgattc aggaggaagc attaagacta
    45061 agaaggaaat agaagctttg gcaaataaaa ataattttaa cttttatgat gaaagtgcaa
    45121 gcaatgaaag tgaaaaacaa gatttaaagg ttattaaaat atttgtatat ggttttatag
    45181 tagtgatatc tttagtgagt gttacaaata ttctaaatac agtaagtaca agtataaatc
    45241 taagaaaaag agaacttgca gcaatacaat ctataggggt tactcctaaa ggatttagga
    45301 aaatgatata tttagaaagt tttatatatg gtatactgtc attgttgttt ggaataccaa
    45361 ttagtattgg tataattcta attatgaata aacttatttc aggtgtaatt gaattttctc
    45421 cgattatacc gtggacagcc atagttatct gtatagtaag tgtttttata ataactttta
    45481 tagcagggta tataccaatg agtaaattaa ataaagaaaa tataatagat aatataagaa
    45541 gagaaagtat atagatataa aaataattat agaaggaaag gcacattatg gaaaaattga
    45601 gagttattga aatgataaaa aataatccca atattatagc tacaatagat aatccaactg
    45661 atgaaatgaa attgttagct attaaagaaa atgggcttgt actagaatat ataaataatc
    45721 caaccagaga gatgcaagaa ctagcaatag ataataatat tagagcaatt aaatttatag
    45781 ataatccaac agaagatatg atgataaaag cagtaaatga gggatggagt atactggatt
    45841 atatcaaaaa cccaactgat aaagttattg aaatggctat aaatcaagca ggatgggcaa
    45901 ttaaatatgc taaaaatcca agtgaagaat tacaactgtt agcagtaaga aaaaattatg
    45961 attcgataaa gtttataaaa caaccttatg aaagtgtaca agaggaggca gtgagaataa
    46021 gttatgatgc cttgagatat atagattcac ctagttataa tgcagaactt atagctataa
    46081 aaaataatga agcagctatt agctttataa ctgatttaga taaaaataaa atgttggaat
    46141 ttttaaaagt gaatatttta gtgattaagt acattctgaa aaaagtatct aaagatgaat
    46201 tagagagtgt attaaaagaa gtattatcca aagaagatgt tgaggaaaag tatattagag
    46261 attttttgaa ttgtagtgtt atagatagaa atagcgaaag tataccaata gataaaatta
    46321 tgtttattta taaatatgga agtaagacag caaaaaaaat agctgtagat gagaaattaa
    46381 agattatgta ggagagagaa aaatgaattt tatagacaca ttaaaaagcg ttgacttaat
    46441 attatccact ggagaagtac ctttaatagt aggtgaaagt ggaataggaa aaacagcttt
    46501 agcaaataag cttgccaaag aaaatgattg gagtttaatt gttattgatg gaaacttact
    46561 taaagagggt gaaataggtg gtcttccaac tatagaatct tatgtaggag ttaattctaa
    46621 tggatataag actgaaaaga aaacaacagt gtatgctgtt cataacaaat taagagaaat
    46681 tgatgaagag atatctaaaa gtaagacagt tcttttattt atagatgaga taaatcgttg
    46741 tgagcataca gtacagcaag aacttatgaa tttaatttta aatagagaaa ttaatggata
    46801 taaactgcat gatgatgtaa agattttagc agcaatgaat ccatcaagta aatatggttc
    46861 agattttgat tatcaagtgg tagatatgga tgcagcccaa gaaaataggt ttgtttggtt
    46921 aaatatggag agtgaccata cacaatggat aaaatgggca atagatgagg gtattgaaag
    46981 aaaagttatc gagtttattt ccacttttcc agaatatctg cataaaataa atgaagatga
    47041 tgtaagagcc actcctagaa gttatgagag agtatctaaa atttataaag tttataaaga
    47101 aaaaaataat tctattccta gagcagtatt tttaaatgtt gtaaagggta atgtaggtaa
    47161 agttattgca gaagaattta taagttttat tgaatcaaac tctgaaccat taatatccta
    47221 tgaagatgtt tttttaggag aatctattga tgagtctatt gtagaaagag taaaaaatga
    47281 gagtcataca agactttatc tatcagctat gaacattcta aaagacttag aattaaatat
    47341 taagaatgat aaatatgaat caaaccacta tattaataga tttattgaat ttttaaaaat
    47401 gtatcctgta gatttaatga taggtattat gaaggatatt agaaacagtt atattgaagt
    47461 atataaaaaa gctatagaaa atgaagagtt tgtaaaatca tattttgaat cttatagttt
    47521 aataagggga taatgtatgg aaaattattt tgataaacaa gcaaaagagc tttataataa
    47581 agcaagtgaa attataaata ctcattctat gctaaaggca aatcgtgcta atgagaaatt
    47641 tgatatagat ataccacaag attttaagta tgagtttttt agtcttgtag ataaagtgaa
    47701 tttaagtctt atggaagaag aagataattt ttatggatat tttttgtttc agatgtcaag
    47761 agaaataaga tttgatataa gtagtcctac aggtgtgaat tttaagggag ctaaatatat
    47821 tatatatttt aatccaataa tctttttaac gcttgacata aagcaaatgg agactacaat
    47881 taaacatgaa attcatcata tattatctat gcatttgatg agagcaaagg agttaaaagg
    47941 aaagtatagt acattagcaa ttaatatggc aatggatata gtagtaaata aatttctaaa
    48001 caatttacca ccatatgcaa ctaccttaga gtgggtaaat ttaaagtatt ccttaaaact
    48061 tgaaccatat gaaccttttg aatattatgt agaaaagatt cagactgaat tagatttgat
    48121 ggaagtggat gaagatggtg aggaagatga tagtgataaa tatggagata tagaaattga
    48181 ttatagcccc gaaagaactc atgatatatg ggatgaatcc aatgagatag atgaaaatac
    48241 ccttagagaa tttactgaaa aatttattaa cagttctcaa aaaggtaaag ttcctgctta
    48301 tttagaaagt atgatatcat cacttaaaaa tagtaagggt gaattgccat ggaatttata
    48361 tcttaataga ataatgggaa cagttgaaaa taataaaaag aagactataa caagaagaaa
    48421 tagaagacaa ccaaatcgtt tagatttgag gggagaactt agaagtcata aggcagaaat
    48481 agcagttgca cttgatgtaa gtggaagtat tagtgatgaa gagtttaaac aagctattaa
    48541 agaagttctt agtatagtga aaaactataa tcatgaaatt acaattatag aatgtgataa
    48601 tgaaattaga cgtgtatata aagtgagaac tgaaaaagat ataaaagata gaattaggat
    48661 aggtggaggt actagatttt ctccagtctt tgagtatgct aataataaaa agattaattt
    48721 gttagtctac tttactgatg gtaaaggtga aaataaacta caagtaatac ctagagggta
    48781 taaaatttta tgggttattt ctggaagagg agataaaatt tcattaaaag aaccttatgg
    48841 agcagttaaa aaacttacta aggttaaaac aaatgatgaa atattagaaa taaatgatgt
    48901 aagaaatgat gggtactcaa tgaatagcca agcaccaatt ttataggtat tcacaggaga
    48961 taagctttat taatttattt tgatatgctt gttataaaaa tctaaaaaat acattaatca
    49021 atggttaatg tattttttaa ttttaataat ataagtttta cttacattta agtcttaaaa
    49081 tgtgttaaaa tataatatat agcagatagt tttggcaagg tggatttagt tgtcaaaact
    49141 atttttttta ttaaggatgg tgatgttttt gtttaagatt gatgattata taatgtatgg
    49201 tatgacagga gtctgcaaag tcatggatat aacaaatgaa cgatttacaa atggaataaa
    49261 aaaagagtat tatgtattga gtcctattta ttctaataat acagtaataa aaattcctgt
    49321 agataatgaa aaagtaccaa tgagaaagtt gctttctaaa attaatgtgc tttcattaat
    49381 aaatgatatt cctaatatgg atacatcatg gatagataat gaaaaattaa gaagtgagca
    49441 atttaaaaaa atactcagag gtggtaaatg tgaagagtta ataaaattag taagaagtat
    49501 agataataac agagagtatg taaaatctat tggtaaaaaa acacatcaag cagatgataa
    49561 tataatgaaa gaagctgaaa ggttattaaa tgaagaattt gcaactattt tagatatttc
    49621 tcctaatgaa gttagttcat atatttcaag tcatatacct caataaagtg ttttagtatc
    49681 ctttatttaa tctattttaa gtattattta tgtatgctgg ttttggtaaa ataaaatata
    49741 taattaaatt atataaaaaa taataatgat tgtattgaag aattacagaa tagtgcggag
    49801 agcccactcc tttaggtgtg agatggatat tacttaaaga tttaaattgt tattgtagat
    49861 gtttttgtac tttttaatat aaagcaagat taataagtgt attgtaagct ttaagtgaaa
    49921 ttgatactat aatgagttac ttagatttta aaatatataa tattataaaa aatcctttta
    49981 ggttttgaat gaataagatg gatactatgt tgaatagaat ccatcttatt taagttttat
    50041 ttatgttgtt tatttgtaag cattattttt gtacatgaaa acacagtgta aaaatatgct
    50101 tagaattatg aagttttatt aaaaacatat tcgacaaaat aagactaaaa atattcttaa
    50161 acttataact aagataaata ttgtatattt atagtgtagc ctgaaaaatt gtggatgtac
    50221 gaaatttatt tagtatttta ttgaaacaaa gtagaagaag tactatagtt tatttttgaa
    50281 tagattgtta ttttttagtg aaaaagttat taggttaata cataaatata atagtttata
    50341 aatagtttaa gcatgttaaa aaagtagtta ttagagatat atagttacat tgcttataag
    50401 atacttaaaa tgatagcatt cacttatatt tagaaaatta agataaaaat catttttata
    50461 tagtaaagca tacctaaatt tagaaaataa ttgaatttat aaaattaatt aaatacataa
    50521 aaaagtattc aatcaactta acaaattttt ttaaatttaa tttaaatttt ttattctatt
    50581 aattattaat attattttca aatcaatgca gttataagaa gtgtataatt tgattattat
    50641 atactgcata caaaaatata tttgagcaaa taagtaaagt aataaaaaaa tcaagatttc
    50701 atatctaaaa acaattctga acattaattt aatttatatt ttcataggaa atattttata
    50761 taatatactt gataaatata atttgaattt ttctaattat ttactgtcga ttaatagatt
    50821 tttttcttgc atataagtgc atatttatgg tacgatttac atggtgaaat aaaaaagggg
    50881 aggtgaaaaa taaatattcg tgaaaaagtt ttcagtttga ggtattttat gaataatata
    50941 ttttgaggta ttttataaat aatatattat acataaagag tataacctca ataaatagta
    51001 tcaaagcgaa tatatgggta attactttaa aataacagtt tttatgttta gattcacagt
    51061 gtttattata aactaatgtg taagaaatag ggctaatctg tgaatagata gtagtttatt
    51121 tatttaagtt gagaattggt tgggtgaagt aatatataaa tttaaaaagt aaataaaaac
    51181 attatttgaa caaaatatat gttgctttat tcgagactcc tttaaaaaag cactaaaatg
    51241 taattacaga agttgctaca aaagggggat tttagtttgt aaaatactat cacgtaaaaa
    51301 ataagaattg catatggcga aggttttttc atggtattag atgagaatat attaatttat
    51361 aactatatct gaaaatagtg aatttatata atttaaattt atgattaaga agtgtattaa
    51421 ttttattcca tgagaatatg tactctacaa ataaatgcgc aattatctta ataataatta
    51481 caaattgttt tacaaaataa taatattata tctttcataa aagaaagaat ttggacaaaa
    51541 cgtaaaaaat aaaaatacaa ttaagaaagg atttaaaatt atgagctcaa cagtaaaaaa
    51601 gaagggtaaa tttcctatgg gattttatat ctgctcaaca actttctcat ttgaaagagc
    51661 agcatattat gcttcaaagt acttaatata tatattcctt acaacagcta tagttcatgg
    51721 tggtcttgga atagataaag gacaagctgc tataatgcaa gccaaccttg ttgcattcac
    51781 ataccttgca cctataattg ggggatatat atcagataga tggataggag ctagatatac
    51841 tatacctata ggtatgctta tcatgggggt aggatactat cttggttcta ttgcaactac
    51901 agtttctatg gtaaatgcaa tgataatctt agtttcgatt ggtactgcat tctttaaagg
    51961 taacgtatct gcggtaaatg gacagctttt tgatagtcaa gaagaacttg atacagcatt
    52021 ttcagtacaa tattcttttg ttaatatagg ttcttttatt ggtactatag cagttggtat
    52081 tctttacctt aaaacatttg caaaaaatgg tgtacttgga ttttctcaat gtttctttat
    52141 agcagctgta ctttgtgtaa taggtgcaat atggttcata tatggatgga gattccttgg
    52201 gaatgcagga aagagacctt ttaaagaagg tgtagttgct gaaaaaattg aagaaaaaga
    52261 taagtctcct cttacaagca tggataagaa gagaatttgg gctattatac ttatatcatt
    52321 cttctctgta attttctggg tattctggta tctaacttat cttgcagttt atgattatgg
    52381 tgcagcattt gtaaacatga atgttggagg atttgatgtt cctcttgctt ggtttgactc
    52441 attaaattca cttgtatgta tagtattagg accagttctt ggagcattat ggtttaaact
    52501 tgctagtaga ccacaaggag atatgagttt atttaaaaag acaggtcttg gattaatatt
    52561 cttaggtctt gcattcttaa tgcttgttgg tgcagaattt tcaagagggg ttggagctcc
    52621 tgaaactgct aaagctagta tactatggat aatcatgttt ggtattcttt taagtcttgg
    52681 tgaaatgtta ttctcaccac ttggtaactc ttttgtaagt aagtatgcac ctaagaagct
    52741 tctaggtgtt cttatgggag tatggacatt tgctactttt atagctggta aaggatacgg
    52801 atatatatat gcatttactc ttaaatttga tatgattaaa gtatatacta taattccagt
    52861 aatactattt gttgcagcga tattattatt cttatctgat aagacattaa gtagacttgt
    52921 tgaggacgat aaataatcag taagcaatta ttatgtttta taggttaatc tactgtaatt
    52981 atgttgtatt agattgattt ataactaatt aataataaaa ataaaatttt act
//
LOCUS       DAEPXW010000015        51381 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.015, whole genome shotgun sequence.
ACCESSION   DAEPXW010000015 DAEPXW010000000
VERSION     DAEPXW010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51381
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.015"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(73..1233)
                     /locus_tag="KRM55_000894"
     CDS             complement(73..1233)
                     /locus_tag="KRM55_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HBH1593151.1"
                     /translation="MKLNKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGSVSAVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSISDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            complement(1404..1607)
                     /locus_tag="KRM55_000895"
     CDS             complement(1404..1607)
                     /locus_tag="KRM55_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBH1593152.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            complement(1694..2728)
                     /locus_tag="KRM55_000896"
     CDS             complement(1694..2728)
                     /locus_tag="KRM55_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBH1593153.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            complement(3250..4611)
                     /gene="rlmD"
                     /locus_tag="KRM55_000897"
     CDS             complement(3250..4611)
                     /gene="rlmD"
                     /locus_tag="KRM55_000897"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH1593154.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVKEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            complement(4638..5360)
                     /locus_tag="KRM55_000898"
     CDS             complement(4638..5360)
                     /locus_tag="KRM55_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH1593155.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(5360..5689)
                     /locus_tag="KRM55_000899"
     CDS             complement(5360..5689)
                     /locus_tag="KRM55_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBH1593156.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESIDLAFTVFEKEKY
                     YENGEHF"
     gene            6019..6945
                     /gene="fba"
                     /locus_tag="KRM55_000900"
     CDS             6019..6945
                     /gene="fba"
                     /locus_tag="KRM55_000900"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBH1593157.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(7080..8711)
                     /locus_tag="KRM55_000901"
     CDS             complement(7080..8711)
                     /locus_tag="KRM55_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1593158.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(9194..10231)
                     /locus_tag="KRM55_000902"
     CDS             complement(9194..10231)
                     /locus_tag="KRM55_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH1593159.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(10250..11035)
                     /locus_tag="KRM55_000903"
     CDS             complement(10250..11035)
                     /locus_tag="KRM55_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1593160.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(11068..12201)
                     /locus_tag="KRM55_000904"
     CDS             complement(11068..12201)
                     /locus_tag="KRM55_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH1593161.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(12249..13376)
                     /gene="hadC"
                     /locus_tag="KRM55_000905"
     CDS             complement(12249..13376)
                     /gene="hadC"
                     /locus_tag="KRM55_000905"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBH1593162.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(13376..14602)
                     /gene="hadB"
                     /locus_tag="KRM55_000906"
     CDS             complement(13376..14602)
                     /gene="hadB"
                     /locus_tag="KRM55_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBH1593163.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(14617..15417)
                     /gene="hadI"
                     /locus_tag="KRM55_000907"
     CDS             complement(14617..15417)
                     /gene="hadI"
                     /locus_tag="KRM55_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBH1593164.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(15456..16655)
                     /gene="hadA"
                     /locus_tag="KRM55_000908"
     CDS             complement(15456..16655)
                     /gene="hadA"
                     /locus_tag="KRM55_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBH1593165.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            17332..18330
                     /locus_tag="KRM55_000909"
     CDS             17332..18330
                     /locus_tag="KRM55_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBH1593166.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            18692..19219
                     /locus_tag="KRM55_000910"
     CDS             18692..19219
                     /locus_tag="KRM55_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBH1593167.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            19246..19842
                     /locus_tag="KRM55_000911"
     CDS             19246..19842
                     /locus_tag="KRM55_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBH1593168.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(19907..21490)
                     /gene="asnB"
                     /locus_tag="KRM55_000912"
     CDS             complement(19907..21490)
                     /gene="asnB"
                     /locus_tag="KRM55_000912"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH1593169.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(21555..21692)
                     /locus_tag="KRM55_000913"
     CDS             complement(21555..21692)
                     /locus_tag="KRM55_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593170.1"
                     /translation="MKNKKFNVITLIILDNHIYAINKEQISTNSKRIYFEKSRFFSDY
                     K"
     gene            complement(22056..22892)
                     /locus_tag="KRM55_000914"
     CDS             complement(22056..22892)
                     /locus_tag="KRM55_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1593171.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(22916..24382)
                     /locus_tag="KRM55_000915"
     CDS             complement(22916..24382)
                     /locus_tag="KRM55_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH1593172.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIESNSIDFK"
     gene            complement(24385..26247)
                     /locus_tag="KRM55_000916"
     CDS             complement(24385..26247)
                     /locus_tag="KRM55_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1593173.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGKRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(26494..27357)
                     /locus_tag="KRM55_000917"
     CDS             complement(26494..27357)
                     /locus_tag="KRM55_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH1593174.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLSFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(27412..28344)
                     /locus_tag="KRM55_000918"
     CDS             complement(27412..28344)
                     /locus_tag="KRM55_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBH1593175.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(28430..28981)
                     /locus_tag="KRM55_000919"
     CDS             complement(28430..28981)
                     /locus_tag="KRM55_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1593176.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(29210..29701)
                     /locus_tag="KRM55_000920"
     CDS             complement(29210..29701)
                     /locus_tag="KRM55_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593177.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(29729..30289)
                     /locus_tag="KRM55_000921"
     CDS             complement(29729..30289)
                     /locus_tag="KRM55_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH1593178.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(30441..31598)
                     /locus_tag="KRM55_000922"
     CDS             complement(30441..31598)
                     /locus_tag="KRM55_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1593179.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(31635..32576)
                     /locus_tag="KRM55_000923"
     CDS             complement(31635..32576)
                     /locus_tag="KRM55_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593180.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLISTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(32663..33355)
                     /locus_tag="KRM55_000924"
     CDS             complement(32663..33355)
                     /locus_tag="KRM55_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1593181.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(33463..34275)
                     /locus_tag="KRM55_000925"
     CDS             complement(33463..34275)
                     /locus_tag="KRM55_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBH1593182.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(34326..35237)
                     /locus_tag="KRM55_000926"
     CDS             complement(34326..35237)
                     /locus_tag="KRM55_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1593183.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQITSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(35296..36027)
                     /locus_tag="KRM55_000927"
     CDS             complement(35296..36027)
                     /locus_tag="KRM55_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBH1593184.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            36116..36367
                     /locus_tag="KRM55_000928"
     CDS             36116..36367
                     /locus_tag="KRM55_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593185.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            36600..37019
                     /locus_tag="KRM55_000929"
     CDS             36600..37019
                     /locus_tag="KRM55_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593186.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVPDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            37044..42101
                     /locus_tag="KRM55_000930"
     CDS             37044..42101
                     /locus_tag="KRM55_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBH1593187.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSNLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(42287..43024)
                     /locus_tag="KRM55_000931"
     CDS             complement(42287..43024)
                     /locus_tag="KRM55_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593188.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(43043..43978)
                     /locus_tag="KRM55_000932"
     CDS             complement(43043..43978)
                     /locus_tag="KRM55_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1593189.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            44186..46762
                     /locus_tag="KRM55_000933"
     CDS             44186..46762
                     /locus_tag="KRM55_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1593190.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGADHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YTNKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            46774..47445
                     /locus_tag="KRM55_000934"
     CDS             46774..47445
                     /locus_tag="KRM55_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593191.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            47472..47813
                     /locus_tag="KRM55_000935"
     CDS             47472..47813
                     /locus_tag="KRM55_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593192.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENEDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(48173..50815)
                     /gene="adhE"
                     /locus_tag="KRM55_000936"
                     /gene_synonym="adhC"
     CDS             complement(48173..50815)
                     /gene="adhE"
                     /locus_tag="KRM55_000936"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH1593193.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        17114 a         8684 c         6141 g        19442 t
ORIGIN      
        1 aaatttatat ttcttcaata aaaaagacaa tcttaattaa ttgtcttttt taatatatat
       61 ttggctaata cattatttta cacaaacatt acaagggtct attttacctt gtgacttagc
      121 ttgttttaat gttactttat ttattgtttt acttcttttt agtgtagaac aattttttgt
      181 tagatgatat gattttccat taggagttac atatactgta cttttatcag ttaatccagg
      241 attattagag ctaggctcat tacttggttt gttcgtatta tttgaattag tatcttttac
      301 aatgcctgta tttgaatccc caacattatt agttatattt aaacattgtt ttataacaac
      361 atcatcaata tttccaatag cagttatttt acttgcattt tttaatatac tcttattact
      421 tccatttcca actaacacta taggtgtttt ttgtgcaatt gtagaaccaa ctaaagaata
      481 aactaaatca gtcccacttg ctatgtaaaa ttcttttgag ccattataaa atttatttat
      541 tatttgttta tttgtatcgt atctatctac tccacctatt cttgttgctt tagtttcatt
      601 tattaactta tcactaatac tgacttttcc accaattgca taagtttcta atccatctgt
      661 agcaaaactt gtagtgtttc catcagttaa tactattgga gatttatctc taactgctat
      721 agaagcaaca ctcatagcat ctggttcacc tttaaaagca ttagttaata ttactttttt
      781 aacagcactt acacttccta tttcttttgc aactttatga cttgtatcta ttctatcagt
      841 tccacttatt ctatttatgc ttattttttt atcacttaat attttctgaa ctgatgctcc
      901 tatcgaattt tttcctccga ttagatatac ttcttttacc ttttctaatc tttttaatgt
      961 ttctgaaggg attgtatctt tcttagttaa caatattggg gcatttttag ctcctgacaa
     1021 tccacttgct gacaatccat cagataatcc attttcagaa ttaataagta ttgcaatatc
     1081 ataattttgt ttatctgcta ttaaacctgc tgtttcatac ttatttgtac cttttattga
     1141 attaatagaa ctaagagcgt ttgatgttgg acaactagca atcaataatg aaacagacat
     1201 ccctattgcc aatagtgttt tgtttaattt cataatgaaa tcctcctata aattttataa
     1261 tattacttaa atattataat tctacataaa agaatatttt cctttatgaa attagtttat
     1321 atttcaaaat tttgtcactt tttaaatcta tatactaaaa aatagactat ttgtaacagt
     1381 ctatttctta gtatatcaaa tatttattta ggtttacgtt tctttgtact agtttttgta
     1441 tatgatattc cagttccagg tatactcaat gtagctgatt ttcttccttt tgaattaact
     1501 gacactctag cacctttaac accagcactt atacctacac tcttcttacc taaatttaat
     1561 ttgagtcctc ctcctagatt tatgcttttc ctaaagttaa atcccataga tataaccttc
     1621 ccttctatat tttaaatatt tatacttaaa attatatttg ttatacactt gccatcattg
     1681 gtatatctag catctatatc tttttacgtt ttttcttctt atatactact ccagcaacta
     1741 cagctgctgt tccagctcca accccataag tagcatttct acttttctct tcctctcttt
     1801 tttctaaacc ttcatcatat acacctttta acttagtttc aatagacttc atttcatctg
     1861 gtatactaaa atcttcttca ttgtaacctt gattatatac actttctttt gctttaggta
     1921 acttaacctt accattatca tatccttctt taaaccaatt agcatattta acattaccta
     1981 tagttgatgt gtcaaatctt tctcctttga tagcactctc aaatccttga gtagtgtaat
     2041 cattttttaa ttgttcttgt atttcgtcat aagcattatt ataagcatct ataaattcag
     2101 aatctatgtt ttcttcaaat gtcatttttt ccttatcttt attgctatcc tctatccctt
     2161 tagctttata ttcttctatc tttttagtct tatattcatt gtatccagtt gaatatccgg
     2221 tatcataagc attttttaaa acttcttttt catatgtatt attagattta gcacctgtaa
     2281 gccctaaatt atatccagtc tctttagcca ccttttcttc ctcttctaat ttagccttac
     2341 ctttttcata tccttctgag tactttgatt catatgtatc actataatct ccactataat
     2401 ttgatgaact ataatttcct ttatacccat cttcataccc ttgattatat cctttttctc
     2461 caacagacct cttttgcttt tcttcattat taaccgaagt tgttgttcca gaactgcttc
     2521 ctcctccagt ataaggacaa ccaccattat tatgtaaatg agctggataa ccaccacaat
     2581 gatagtgata acttcctaat ccagatttat ttttattatc acgatgacct cctgatgaat
     2641 cagttcttcc tgaatgagca tacgaaaagc tccccacact aatcatagtt atactcattg
     2701 caacagctat taactttttc ttaaacataa tctatttccc cctaaaatat tctatgattt
     2761 tattatatca gtcaatatat tatgtttaaa ccgttaaaat tcgacaatgt aaatatttga
     2821 tgaattgtat ttgtaaataa atcttttagc atatcttgaa tatctgtagt tgtgttgaca
     2881 tcatattctt caataagttt tttaatattt cgtttttgtt aaacataaaa agcgtgcact
     2941 ttcctttgta tagtgatatt tgatatttta attatcacta ctttagaaga atacacactt
     3001 tattttaaaa accctgatac tatgttatta gaaaatggta ctaatataaa agatatccag
     3061 catatactcg gacatgctaa aacttcaaca actatggata catatttaca tgtaactaac
     3121 aacatgagaa accagacggt aaatattttt gaaatcattg tagaataaat ttgccaccca
     3181 aaaataatta tggtggcaaa taggtggcaa atctactttt aagacacaat ataaaagtct
     3241 gaaaccctgt tattctctaa taagtttaac tacagtctca caatgtggcg tatttgggaa
     3301 catatccata cacttaacca tcttaatctc ataaccatac cccttaaaat caaccaaatc
     3361 aacaaccaaa gacttaggat tacaagaaat ataaacaatc tccttagcac caaatccaca
     3421 aatatcccta atagcatcct tatgaatgcc tggtctagga gggtcaacaa taatcaaatc
     3481 aggcttgtcc tttaaatcct taacaacctt agccacatcc ccagcaataa actcacaatt
     3541 agtaagtcca ttcaacttag cattctcatt agcagcaaca acagcttcct taactatctc
     3601 aataccatac actttcttag cagcaccagc cataacctgt ccaatagacc cagtaccact
     3661 atacaagtca aatacaactt tatcattgta atctccaata aaatccctag caatactata
     3721 aagaacctct gctcccttag tattggtttg gaaaaacgaa aatggtgaaa tcttaaactt
     3781 aagacctaaa atttcttctt gtatataatc tcttccatac aatactctta actcatcaca
     3841 ttggactgca tctgctaaac catcattaat agtatgaagt acacctacta actcagcttt
     3901 taaatcaatc cctaaaagca tatctttaaa ctcatacata tcaaaatctt cttgagaaga
     3961 agttactata ttaaccataa tctcattagt atgaatccct tttctaacta caagatgtct
     4021 caaatatcct ttgtgattca ttgttctata ataaggaagc tttttttcat tgaaaaactc
     4081 tacactagaa actaatatct ttgagaagtc ttcatcaacc aacatacact cctcaacagt
     4141 ttgtatatct atatgctttc cttttttatg aagacctaat gtcaaaggtc cattttttac
     4201 ttcatctcca aaagtatatt ccatcttatt tctataatat ttgttttctg gacttccttc
     4261 tatccctaaa aactgaaatc caaataaatc ttgctttaaa aataaatcca taacttgttt
     4321 ttcttttatt tctaattgtt tttcatatgg cacagacaat agtgtacatc ctccacactc
     4381 tctaaagtgc ttgcaagttt cttcagtttc aagtggtgag ttctctaata attctatcat
     4441 cttaacttca gctttcttac ttctaacttt tttaactcca gctctcacct tttgaccact
     4501 tattccaccc ttcatatgga taactctatc tccaacttgg cttaaagatg taccaccaaa
     4561 ttccatttta tctacttcaa attctataac atcttttttc ttcacagaca ttcctccaat
     4621 ttactatagt atctttatta tctttcttca atcaatttta cttcttcatc tgttaactct
     4681 ctatactcac ctaactctaa actttcatcc aattttaaat tgcccataga caatcttttt
     4741 aagtatacta cttttttgcc tacgctttca aacattcttt ttacttggtg aaacttacct
     4801 tcatgtattg taagctctat ttctgattca tcatcacttt ttaatatatt taactgtgat
     4861 ggcatagttt tatatccgtc atcaagcact acaccttcta aaaaagcttc tacatcttct
     4921 tcagtaacta ctccatcaat ttttgcataa taagtcttag gcacatgctt cttaggagat
     4981 aaaactctat gagaaagctt tccatcatta gttaaaacta ataatccctc tgtgtcttta
     5041 tctaaccttc caacaggaaa tggttcaaaa gctaagtatg ataaatcaat taaatctaat
     5101 actgttgggt catatttatc tgtagttgct gatatatatc catcaggttt attcatcatc
     5161 aaatatatat attctctata tataacttct tctccattaa ataatatctc atcattttca
     5221 gtgtctactt gagttcctgg atttgaaact tcacttccat ttactactac agacccttgt
     5281 ttacaatact tctttatttc acttctactt ccataaccta aatttgaaag aattttatct
     5341 atacgttgct ttttagccat taaaaatgct ctccattctc ataatatttt tctttttcaa
     5401 atactgtaaa tgctaaatct atactttcta catctaaatt atttcttata ctatcagtta
     5461 ttattcttgc tactatatct tgtacttctt gtcctctatc aaaccaagct acttcaacaa
     5521 aaggatatac atctgctatt ttaccatctc ttattgcaac tgactttata cattctattt
     5581 caaagtagtc tcttggacat tttacagctt caactaaatc atttatcatt ttttcactta
     5641 ttttacatat atcattttca ttaattcctc ttatttttat ctgtggcata gtttatctcc
     5701 tttattttaa atttttagtg aattatcatc cacttaattc ctttcgataa cgtttgaagt
     5761 ggtaacttct tggtcaaggc aactattgtt atcagtatct ccaaactaat aaggtagttc
     5821 ctacccttat agttagcatt atatagctag ttttcctaaa ttgtttatat tctttattat
     5881 tttatttaat cctattgtct tctatttaac attatacttg taatttatag ttattacaat
     5941 ttactatata ctttttttga tttaacgtta taatataagt gatgggtaaa ttttaaaagt
     6001 taataggagg agtttaaaat ggcattaatt actacaaaag aaatgtttaa aaaagcttac
     6061 gaaggtggat ttgctatagg tgcatttaac ataagtgact tagaacaatt acaaggtgtt
     6121 ttaaaagctg ctaaagctaa aaattcttat gttatgatac aagcttctat gtcagctgtt
     6181 aaatatgctg gacctcatac attagttgaa atggttaagg ctgcttctga tgaaataggt
     6241 gtagatgtag ctcttcactt agaccatggt ccaaatatgg atgctattaa aacttgtatt
     6301 gatgctggtt tctcttcagt tatgatagat ggttctcatt ttgactttga agaaaatgtt
     6361 agaataacta aagaagctgt tgaatatgca cactctaaag gtgttgttgt tgaagcagaa
     6421 cttggtgttc tagctggaac agaagatgat gttacttctg atgttcacaa gtatactcaa
     6481 ccagctgagg cagttgagtt cgttgaaaga acaggtgttg attcattagc aatagctatt
     6541 ggaacttctc atggtgcttt caaattcaaa ggagaagcta aattaagatt cgatatacta
     6601 gaagaaatcc aaagcaaatt accaggtttc ccaatagttc ttcatggtgc atctgctgtt
     6661 gaccaaaacg ctgttgctac atgtaatgaa tttggtggaa atatagctgg tgctaaaggt
     6721 gtacctgtag atatgttaag aaaagcatct tctatggctg tttgtaaaat aaacatggat
     6781 actgacttaa gactagctat gactgctgct atcagaaaat tcttagctga aaatccaaaa
     6841 gaatttgacc caagaaaata cattggtgct ggtagagatg ctatacaagc tgtagttgaa
     6901 agcaagatag atgatgtttt aggttctgct aactctataa actaatataa cttttaaata
     6961 tttataaaag aaaagagatg acttaaagta attaaattta tttttaagcc atctctttta
     7021 agttgtataa attatgtatc ttataatatt ttaattatat tgtcttttta aactgacagc
     7081 taaacgtgaa tatgtccact ctttatcttt ctatggatgg tagaaggata tatacctata
     7141 acttcagcag cctttgttat tgaaccatac ttatttatag ccttacttat cattatttgg
     7201 tccactattt tatatgcatc attaagattc ataattccat ttaccactat tggtgataaa
     7261 tcatctgttt cattatcaat catatctaaa tttatcagca tgttaaattc atcttctcca
     7321 attacatttt tagctgataa tactacaaat ctttcaatga tgttttttaa ttctcttatg
     7381 tttcctggcc aagaatattc ttctaataac tcaataactt taggcgaaac ttctacttct
     7441 ctattgtact tttcattgta aagttttaag aaataattta ctaatggtac tatatcctct
     7501 tttctttctc taagaggagg tatttttact ggaataacac ttaatctata gtacaaatct
     7561 tgtctaaatt taaggttatt tctaaggtct tcatgagaaa tattagtagc acttatatat
     7621 ctaacatcta tttttatagg cttactacca cctattctag taatagtatt ttcttgtata
     7681 accctaagta attttttttg catctgcatt ggtaactcac ctatctcatc caagaaaata
     7741 gttccaccat tcgcctcttc aaaaagtccc tttttacctt ttttcttagc tccagtaaaa
     7801 gaaccttctt catatccaaa aaactctgac tctaataatt catttggtat agctccacag
     7861 tttatagcta taaaaggttt gtctctcctt gaactatact tatatattgt tcttgctatt
     7921 atttcttttc ctacacctga ttctccattt ataaatatag aagaatctga ggctgcagct
     7981 ctcttaacaa ctttttttat attgtccata atcttacttt gacttatata ctctgtgtct
     8041 tctgatatat cactatattt tatctgagat tcaagcttaa taacccttga aatatctctc
     8101 cctgttagta ctcctcctgt aagctttccc ttagaatccc atcttggaac tgccgtatat
     8161 gcaataagct tcccatctgg gtaaacgata tttctataaa tctttttctt cactttaagc
     8221 atgtttaata ttattggttc ttcaactaat ccttgtctca caaggtctgt tatatttcta
     8281 ccaagtacct cagttctttt aaaaggtaat atctcatcac tgacagtgtt catcttttca
     8341 attaccccat ctttgttaaa cacaacaaca acttcatcta tatgctctat tatatcttca
     8401 attactttat cagatattag agacttctca aataaataaa ctatattatt ttcattatta
     8461 ttatctttca tattgtatat atgtgcagtc atccttaact ctctgaaagc tattttcttt
     8521 ttactatctg tcagtatttc tgttttgtca aaatttgaat ctaattcatt tatatttcta
     8581 ggctttttta tatctagaaa actaaaaata ctatctatta gatgattaca gtatattatt
     8641 tcgcctgatt ctttacataa aatggctgga ttttctacat gttctataag ccctattaaa
     8701 ttattatcca ttaatattcg cacctttcat taagtaattt attgaactac atacaaaatt
     8761 tattgtttgc ttacaataaa taccatcagc acatataatc aactccttat aatattcgtc
     8821 ttttcaagta gtttatttca ttaaaacgta actaagatat aattttaatg attatagttt
     8881 gttaaaaatt tcattttgct tttaattgta ttttatcaca tatttagtaa ttatttgtct
     8941 atttaataca atttaattaa atttaagatt tatttaaaaa aacaaagata atccttacag
     9001 aatataactc acaatttgta agcaatatac atataaggat tatccagatt atcttgtatt
     9061 ataaaatttt attcaaacag actttttaat aactgacaaa tacacactag caataactta
     9121 tcaaagggtt aataattatg ttactaacta ataagactta ttcaatcagt aatatttata
     9181 tagtttgtat ctattaagct tttatagctt ctaataaatc atcaacgcta tctaattttt
     9241 ctataagcat tggaactatt tcatgtaagt ctccaactac tccatagtca gcgatttcta
     9301 aaattggagc tgctgggttt ttgtttatag caattatgaa atctgatgat tgcatacctg
     9361 ctaaatgttg tattgctcct gatataccac aagctatata taggtttggt ttaacagtag
     9421 ttcctgtttg acctacttgg tgagaatggt ctatccatcc agcatcaaca gccgcacgag
     9481 aagaaccaac tactccacct aatttgtcag ctaatttctt aagcatttca aatccttctg
     9541 gtccacctaa tcctagacca cctgatacta taacatttgc atctgtaaga gatactaaat
     9601 ctttcttagt tttaactgtt tctaaaacag tagttcttat atcatcttga gttattttgt
     9661 agtctaatgc tataacttca ccagttcttg tttcgtcttt ttcagcttta tccataacac
     9721 caggtctaac tgtagacatt tgaggtctat ggtttggaca aatgattgta gccattatgt
     9781 ttccaccaaa tgctggacga gtttgtttta ttttcttatc ttctgggtct atttctaact
     9841 tagtacagtc agctgttaat ccagttccaa ctcttgaagc tattctaggt gctaagtctc
     9901 tacctatatg agttgctccg aaaagcatta tttctggttt tatttcatct attgcatctt
     9961 ttattacttt tgtatatgca tcagttgtat atttttctaa aagagcatca tctgcaacat
    10021 aaactttgtc agctccaaaa gtgattaatt ctttagctaa tccatcaaca tcttttccta
    10081 ataatattgc acaaagttct gcatctactt ctttagctaa ttttcttcct tctcctaata
    10141 attctataac tactggagct atttttcctt ctctttgttc tgcaaatatc catacgtttt
    10201 tataagaact taaatctttt atatcattca tagtttgtac tcctccaact tatataatgt
    10261 gcttttgttt tagaccgatt attattttac tagctatttc atcagcttta ccttctaaga
    10321 tttctccttt tcctcttggt tcaggagtaa atgatctaaa tactttagtt ggtgatgctt
    10381 ttaaaccaac ttcttcttta tttacatcta aatcatcaat tgtccaaact tttacatcat
    10441 gtttatatgc ttttactatt ttatcaacag acatgtatct aggtgtattt aactctttta
    10501 ctgctgttaa aagtacaggt gtacttactt ttattaattc gtatccatct tctaattgtc
    10561 tttgaactat tatatctttt ccttctattt tgaaatcttg tacatatgta acttgaggaa
    10621 tgtctaattt ctctgcaatt tgtggtccaa cttgtgcagt atctccatct attgcttgtc
    10681 ttcctgcaaa tattatgtca tagtcaccta ctttagatat tcccgctgca atagtatttg
    10741 atgtagccca agtatcagct cctccaaatg ctctatcact taataatatt gcatcatcag
    10801 cacccatagc taaacactct cttagcataa agtctgcttg aggaggtccc attgttataa
    10861 ctgttatagt tacatcatca tgctcatctt taatttttaa agcttcctct aatgcatttg
    10921 catcatctgg gtttaatata cttggaactc catctcttat aagagtacct gtttctttat
    10981 ttattcttac ttcgttagta tctggaactt gttttacgca aactaatatt ttcaaagtct
    11041 atacctccaa tttcattaga ttatttatta ttttaatacg tttgatgaaa ttaccatttt
    11101 ttgaacttct gatgttcctt cgtatattga tacgattcta gcatctctgt acattctttc
    11161 gatttcataa tcttttataa atccatatcc accgtgaagt tgtaatgctt tataagcaac
    11221 ttcatttgca atttctgatg catagtattt agccatagca gattcttgag caactctcat
    11281 tcctgcatct ctcttttgtg ctgcatcata aactaatcct ctagctgcac aaacttttgt
    11341 ttccatgtca gctatagtaa attgagtatt ttggaattta gctataggct taccaaattg
    11401 aactctttgt tttgtatatt taacagcttc atctaaagca ccttgagcta ttcctagagc
    11461 taaggcagca acacctattc taccaacttc tagagtaccc attgctatct taaatccttg
    11521 accttctttt ccaagtaagt tttcttttgg aactttaacg ttttcaaata ttaagtcaga
    11581 agtttcagtt cctcttatac ccatcttatc ttcatgagct cctgttgaga aaccatccca
    11641 tttactttct actataaacg ctgatgttcc tctaagtcct ttacttctat ctgtaactgc
    11701 tattactata gctacatcac agaatggtcc attagttatg aaagtttttc taccatttaa
    11761 tatatagtgg tctccaacta attctgctgt tgtttgttgt ccacctgcat cagaaccagc
    11821 tcctggctca gttaaaccaa atgctcctat taattcacct gttgctatac cttttaagta
    11881 tttttgtttt tgctcttcag taccattgta aagtattggt aatgaagcaa gagaagaacc
    11941 agctgtaaca aaagtagctg ttgaagcaca tcttctagct atttcttcca ttactatagc
    12001 gtaagaaaca tatcctgctc ccccaccacc atattcttct gggatattac tgcttataaa
    12061 ttttgcatca gctaattttt tgattaattc cttaggcatt acacctgttt tatccatttc
    12121 tgctggtaaa gtatctaatt ctttactaac aaaatctctt actgcttttc ttaaaagttc
    12181 ttgttctttg ttatataaca tagcttcctc caattttcat attttatagt aaatttattt
    12241 taatgaactt acgctaaact catcatctca gcaaaagttt gaatacgagt tctggcttgt
    12301 tcattattct gagtttgttg gtcgatttca acatataaag taggtattcc actatcttct
    12361 atatcttttc taactaaagg ataatcgtat tcttctgggt cacagaattt catcatacag
    12421 aagataacac catctatatc tttcttttta acttcatcta ctataagtga cccacgtttt
    12481 ttcttagggt cataagctaa tgaacatcct tctatgtttg accattgtct tgctaatctt
    12541 tctaacgcat catcacctgc tggtacatct gttctgaatt gtcttgtttc ttgtgctaag
    12601 tcgtcagcta caactgatat attgttgtct tctaaaatgt ctaatatatc tttagaatca
    12661 gctaatatac ctgttaataa aactttcttt ccagaacaga cttcttctgg catagcattt
    12721 aattttgcta ttaaatcttt cactagctca gtatgttctt cttttctcat aaagaaccca
    12781 ctcttaatta ctaagcttct tattgatggt tttatagtat tagaatgttt ataagctact
    12841 tcaacaaagt ctctcatagt ttttctatgt tcattgtaaa cttctatact ttcatgaatt
    12901 tttgcttctt ctatttcata tccacaaatt tcttcaagtt ctctttttac gcctttgtac
    12961 tcactgatta agtattttac accagcttca agttttctat tttgtgggtg tactaatgat
    13021 atatatttta tatgaggtac tgctgatttc cagttttgtc ctaaacaaat tagtgtatca
    13081 cacatacctg gtataataac tccagataat tcatcataag caccttttaa tccatattct
    13141 aaacatgatt gcattattga acatgcaaat gcagggaaat attgtttagc taaatctaat
    13201 tctgtttgcc ctccccatat accaactgga agcattccag ctgcatgtat aatttcttct
    13261 gggcaataaa ctgggaaaca acctatagct tttttaccag tttcactttt atattttttt
    13321 acagccgcat ttggattttc aactacttct ttcattttag ataaaatagc ttccattata
    13381 tctcacctct attaagtttt tttctttctt ccattacttc aactaaacct tgaattcttg
    13441 tttcaaattg agcattagtg aaagctctag ggtctgcttg gtcaccatca aatccagcat
    13501 atggtaatcc agtttcttca gctgctcttc tttgcatttc atattgtatt aaactcataa
    13561 gtttacagct tctgttcata tgatagaatg ctccatcaca tttaccctct actaaagaat
    13621 caactctata ttttgtcata cggtctaggt ttacattgtt aaacatagta ctatatgcta
    13681 ctgccattcc atctaaatca ttaacttcat attgtaatgc ccaagcatgt gggtaaacac
    13741 tacctgtcat gttaactcca aatttagcta atgttttcat cttgtatcct atatatggcc
    13801 aacaaggtat accttccatc attattctgt atttttcttc ccctctgaaa gaagatttac
    13861 cagttttcat gttgtcctct aattcttcta taagtaactt aaatgcttct gtagtttctt
    13921 ttttacctct agcacaaact attacagcca tgtaagtaaa taagtcaaat ccattcattg
    13981 gagaaggaga agaatctgct ggtaaactca tagaatactt ccatagtctt ccgttttcag
    14041 ctgatatttt cattacttct tcaaacttct tagggtcaaa tttctttcct gatataattt
    14101 ctagttgttt tatagcttct tcaaattgag ctttaatata atctattctt gattgagtaa
    14161 cttcgtcttc attattgaaa gttgtatcaa tcattattaa aggtatatct aattctcttg
    14221 aaatattttc ataccatttt ataacttggt tacatatatt gttacagcaa agtaggaaat
    14281 ctggagctgg catatccaaa gcttcacatc caccattttc taaaagacca aaatttgttc
    14341 ttgcatatgc acataggtca atagaatatc ctttagattc agctatttca cataattcta
    14401 aagaaccttt tttagctgct actccagctg cttggttttc tggatataat acgtttaagt
    14461 caaatacttc tgctaactct tgaggaaata ctgatgttga ccaacctaca ggtcttcctt
    14521 cttctttagc tttaaatgca tttgcatatt gttcagctaa taaatcatta attactactc
    14581 tagcttcttt tttttcagac attttcatcc ctctttttat atatttttca cttctttttg
    14641 tgattctttt gcttcatcaa aagcatataa cgctgctcct aaagcaccag ttaattgagg
    14701 tatatcaggt acaataattt ctgtgttgat ttctcttgcc atagctctta caataccact
    14761 atttctagca actccaccaa ccataactac atttctttgt actcctattc tttttactag
    14821 gctagaaact ctctttgcta ctgaagtatg aatacctgcc actatatctt caatttttgc
    14881 attttcagat aaatgtgata taacctcaga ctctgcaaat actgtacatg tactgcttat
    14941 tgatacttca ttttgagaat tcatagatat acttccgagt tcagatacat caacctctat
    15001 tatttttgcc attacatcta aaaatcttcc tgtacctgca gcacatttgt cattcataag
    15061 aaagtttaat agtcttccat tattatctaa ttttaatacc tttgcatctt gaccacctat
    15121 gtcaataatg gttcttgtct ctggaattat gaaatttacc cctctagcat gacagcttaa
    15181 ttcacttatt tgcttatcag catctgaata gttcattctt ccatatcctg taactacaac
    15241 ttttttaata tcttctcttg caagacctgt cttgccatat aatttttcta aaactcttga
    15301 tggtccagta gtcccagtac cagaggatat tgtttcagaa gctacaatat cttccccatt
    15361 ctttaagatt actccctttg atgcagttga acctatatct aatcccattg tgtacatctt
    15421 tagcattctc cttttaaaaa atctagaatt actaattaat atcttacaac tttactatct
    15481 ttaaagttat ttattttctc ttcatcgtag cctaaagatt ttaatacttc tacagtatgt
    15541 tgacctactt ttggtgctgg tgtatattct ttaattcctt catttctaaa cataactgga
    15601 gtattaacta agacacctgt atttccgcta tcgtatgttt tcttaaataa gaagtcattt
    15661 gcccaagctt gttcgtcatc taataaatct tcacagcttt gaattttttc aaatggtaag
    15721 tctgcttctt ctaataaagc tgaccactcg tctaatgttt tttctaacat agcttctcca
    15781 actatcttaa ctaaatcttc aacatgatta accattgaat ctatgttatt atatctatca
    15841 tcttctaata tatattctct atttataacc ttacagaatt tgcctaacca cttgttgtat
    15901 tgtattaaag ctaattgaat ccatcttcca tctttacatt tatatgtagt cattaatggg
    15961 ctgtttggat tttctcttga taaaggcatt tcatttccgt attgtgctgt tgttatcatt
    16021 gttcccattc catatatagc tgtatggaaa agacttactg ttactctctc acctttacca
    16081 gtttgagctt ttttatgtaa tgctgctaaa cttcctgctg ctagtgctag acctgcatag
    16141 tggtcaccaa atcctgctgc tgtatttgct ggagatgttc ctttttccat aacagattgg
    16201 ctaactcctc ctcttgcgaa gtatgcagta tagtcaaatc ctggtttatc ttttaaaggt
    16261 cctttttcac catatcctaa tatttgagag aatattaatc ctggatactt atcttttatt
    16321 tggtcataag ctatacccat tttttctaat gcttgaactc taacattagt tacaaatatg
    16381 tctgcttctg ataataattt atgtaatatt tctactcctt cttttgattt tacattaata
    16441 cttacaccct ttttatttcc attttctaat tcaaacatag ggttttcatc atctgatgct
    16501 ggagatttaa atgttccacc cataactctt attccatcac cttctatagg ttcaatctta
    16561 ataacctctg caccccagtc acctaacatt tttgcacaac atggtgctgc gatgaaactt
    16621 gaaagttcta ctactttaac tccttctaaa agcataacgt tttcctcctt aatagtatca
    16681 attataaaat ttcgattaaa tcactcataa aatacttttt tctgatatta actgtctgat
    16741 gtcaaagttc ctaatcttat ctaaaataac ttaaaaatta ttaaaattat tttttattgt
    16801 tttattgtct tacacctata ttgttaagca tttatcgtgc caactttata tttaatcaaa
    16861 atatcgcttg atttgaatgt tttttaacaa tatgcaattg aataatcttt ttcataccgt
    16921 ggcatcttgc cactatccat tgcattttgc tattctttct atgcttataa aagttttttt
    16981 tatatatttt tttatgaaaa agcttgacat ttcaaaaaaa gttttcattg ctaaactcaa
    17041 aaacacatgt tatcattgta attaatcagc aagttagtta actaatttca aacttagata
    17101 attttttaat aatatttaat ctaaaaaata acaatttctt tgataaattt tagagtaatt
    17161 attacattaa ataaaaaatt actaaatatc aaaataacac agggaaaaca atttcaaaac
    17221 taaattttta accttaaaaa ttttgtataa aaaatataac cttatatgct acatattatt
    17281 tctaaatgaa aaattaccat aataatttaa taattacagg agggtattga tatgaaaata
    17341 ctagtatttg gagcacgcga ttatgaagaa ccagtaataa aaaaatggtc tgaagaacat
    17401 aaggatgttc aagtggatat ttatcctgaa aacatgactg aagaaaatgt agttaaagct
    17461 aaagggtatg atggtatatc tatacaacaa actaactata tagataatcc ttatatttat
    17521 gaaactttaa aagatgctgg ggttaaagtt atagcttcaa gaactgcagg ggttgacatg
    17581 atacattttg atttagttaa tgaaaatgga cttatcgtta caaacgttcc ttcttattca
    17641 cctaatgcaa tagctgaatt agctgttact caagctatga accttttaag aaagactcct
    17701 ctagtaaaga aaaaagtctg tgaaggtgat taccgttgga tagctgaact tcttggaaca
    17761 gaagttagat ctattacagt tggtgttata ggtacaggaa aaataggtgc tacttctgca
    17821 aaattattca aaggcctagg agctaatgta attgcatttg accaatatcc aaatagtgat
    17881 ttaaatgata tattaactta caaagattct ttagaagacc ttctaaaaga agctgacctt
    17941 ataacattac atactccttt acttgaagga acaaaacata tgataaataa agatactcta
    18001 gctataatga aggatggagc ttacatagta aatactggcc gtggtggttt aattaataca
    18061 ggggatttaa tagaagcact agagtcagga aaaattagag ctgctgccct tgatacattt
    18121 gaaactgaag gattgttctt aaacaaaaaa atgaatcctg gagaattaac tgacccagaa
    18181 ataaataaac ttctttctat ggaacaagtt atattcactc atcaccttgg tttcttcact
    18241 agtacagcga ttgaaaatat agtttattct agtttaagta gtgctgtaga agttataaaa
    18301 acaggaactg ctactaatag agtaaattag tattttataa atatattttt tcattaatta
    18361 gctattatct aacaaaatag cctttaattt cccaaatata agagagtcag ctcagtatat
    18421 attgagtaga ctctcttata ttatttttta tattaaactt gtactcttct tattcatacc
    18481 aaattaaatt tatattaact tattctaact actcctactc tatacatttt acctattttt
    18541 acttttctaa ttatatacat ttgaatgggt acaatctgta ttttacaaaa aaaacaccta
    18601 acaaactatg aaaattgtat gattaatatt aatatattta taagaaaaca taacaattat
    18661 gttagctctg gatttttagg gagggagtat attggaaaaa atgaataaag ttacttctaa
    18721 aaaaactacc tatattgtta cttcagcatt atttgcatcc ataatatgcc tgacaatagc
    18781 atatatatta catattccag ttggtggaaa caatggatat gttcatatag gagatgcttt
    18841 tatttatcta gctgcaacta ttttgccaac aaactatgct atagctgctt ctgcaattgg
    18901 tgctggtcta gctgatttat ctacaggtgc tgctatctgg gtaataccaa ctataatcat
    18961 aaaaccaata cttgtattat ttttcacttc taaaagtgac aagataataa ataagagaaa
    19021 tatagttgct tcggttgtag caggtatagt aggattagtt ttatacatgt ttgctgaagg
    19081 tataattatt ggaagtttta caagtgcatt tgtaatgagc ttacttggct tattacagcc
    19141 aataggaagt tttattgttt ttataatctt aggtatggca cttgataaac ttgattttaa
    19201 aaaacgttat tttaattaag aatttaaatt tatggaggga aaattatgaa tatcttatat
    19261 acaattgaaa atagtatcta tgtaaatata actaatacat gtccatgtag ttgtgttttt
    19321 tgtataagaa acgaaaaaga tgaagttgca aatagtggta gtttatggtt ggagcatgag
    19381 ccaagtgtag atgaagtaaa agaagccttc aataaataca atttagacga ctatgatgaa
    19441 atcgtatttt gtggatatgg cgaaccatta atgagaataa atgaattgat agaggtagca
    19501 aagtttataa aagaaaaaag tagcataaag ataagaataa atacaaatgg tctaagtgat
    19561 ttaatacata acaaaaaaac agctattctg ttaaaaaatg ttatagatgc agtatcaata
    19621 agtcttaatg ccccaaataa agaagcttat aatagagtta ctcaaccaaa gtttggagaa
    19681 aaatcatttg attatatgtt agattttgca agagattgca aaaaatatat aaaagaagta
    19741 gctttttcag tagtagatga aatatctcca gaagaaatag aagaatctaa acaactggca
    19801 aaaaaacttg atataccatt aagggttaga cataagaatt agcaagtaaa attataaaac
    19861 attaagaatc acctgaatgg tctttcaggt gattcttcct cttgtattaa cattttacaa
    19921 aatagatttc ataccacact aggaatgtgt aaatcatcca aatctttctc caattatcag
    19981 agtttccact aatgtagtca ttaaaaatct cattaatctc atctatgtta aagaatttat
    20041 ctgctatctc actattgaat ttatctcgga tatccttatt atattggtca tcagccatcc
    20101 atatacgaat tggcacaata aatcctaatt tatttctaaa agcaatctct tctggtaatg
    20161 tttttgatgc agctgtacga aaggcaattt tattctcttt tcctttcact ttatattctg
    20221 atggtattct ggatgcaata tcaaatattc ttgtatctgt aagaggcatt ctgacttcca
    20281 atcctactgc agtactcatt ttatctatat taaaataaat atctccttcc aaccatattt
    20341 gaatatctac atttgacatg ttagtaagtg tatctagttc ttctgtttct tcataaattc
    20401 cttttaccac ttcaatagga agcacatcag gattgtattt cttaagaatt tttcttttct
    20461 caccctcatt cataatgttt gtatttccaa tataaaatgt cttcaaattc tctccataac
    20521 actctgcctt atggtatata ttatatccac caaaaaactc atctgctcct tctccagagt
    20581 aacagatatt tgtgttttca gctgctgcct tgcatccaat agcaaaaacg atagcagatg
    20641 catctccagt tggttgctcc atatggtaca ttacataagg tactgacgca aaatactctt
    20701 caggtgtaat tatatatctc gaatttttac acccaagaat attagctgtc tgttgtgcta
    20761 attttgattc atcaaaacgc tcttcctcat aaccacatga acctgttttt tctatatctg
    20821 acattgccaa tatataagat gaatcaacac ctcctgatag gaataactct gcagtttcat
    20881 tctctgattt tacctctggc ataattttct gaagtgttgt atgaatttca tccgtccatt
    20941 cctcaataga cttgctgtgg tcaggatgaa attcaggttt ccaataacga ccaatacata
    21001 ctgttttatt ctgatagaca aggtaatgtc ctggcataag cttctttact ccacggaaga
    21061 atgtattttc acctgctaca tatgtgaaag acatataaat ctgtaacatg tcttcattta
    21121 actctttcac aaatcctggt tgctccataa tcttacgaat agatgaacca tagagaagct
    21181 tcccattttc agtctcataa taatagaaag gttttacccc aaactggtct cttaggcaga
    21241 agagtttctt ttccacagta tcccataatg caaaagcaaa cattccatgc atgtgatttg
    21301 ccatatcata tccccatgtc ttatatgctt ccactaaaat tgctcgttca cgctcatctc
    21361 tacataatga agaatcgatt ccaagttctt cacaaagaac tttccagttt cgaatatgcc
    21421 cattgtattc tagaattttt atcatatatg tgtcttttcg tgttaaatac ttttcttcta
    21481 aatttatcat atgtgtatcc tttcgtatta aaacatttaa cttctaaatt tattaaatgt
    21541 ttatatatat ttattcactt ataatcactg aaaaatcgac ttttttcaaa gtaaattctt
    21601 tttgaattag tactaatctg ctctttatta atggcataaa tatgattatc aagtattatc
    21661 agtgttataa cattgaattt tttattcttc ataaatattg ccccctttat attaccaact
    21721 aaatataata tatcttatgt tacttacata ttctttaaga aattctgaag attttataaa
    21781 gttttttgta ttataattaa ttaaaaataa aattctagtt ataaaacata ttttccatta
    21841 aacaaaaaaa tagttaaaat aaattcataa ccacataaac ttattttaac tatttgtata
    21901 ttttaattat aaatattaac ttaaattttt aacaggatac actcataaaa taaacataat
    21961 gaacaacaaa ataatatgtc tcagtttctt tatatacttt accttctttc aattttctac
    22021 catgtagacg tataagataa tattagtaat tcactctatt gcttaactcg tgcgatatgg
    22081 acaaccaaga aagctatttc ctcatttgtt aacttttttc catatttctt ttctaaaaaa
    22141 tctctaactt ttaatgcaat taacatttct tttggatttg accttttcat ttgattaaat
    22201 aataaatcat caccactgct taacatacta tctgaaaaaa atctttccac aaaaaatttt
    22261 atatgtgtta taaatctcat ataatgcata ctctttttat ctaaggttct attcaaagaa
    22321 aaaacaaaaa tattaattat ttctccaatt actttggcat acttaatcgt atcatatgaa
    22381 tttccatctg aagccatagc atttgcaaaa tggaaagcaa tgttagctgc ttcttcctct
    22441 ggtaattgaa tgcccaatct ctcctctacc atataaattg caaccattcc aaccttaaac
    22501 tcatttggat aataattttt tatttcccaa aatactcgat ttgtaatttt tattccttta
    22561 cgcatccttt caattgcaaa gttaaaatgg tctgctaata ttaagtataa gtttttatta
    22621 aaagatgagt tcaataactt ttctgcctct actattattt cctgtgttat ctttaaaatg
    22681 tcgacaggaa tatcatccat taattctaaa aattgttttg attttgtatt ttcaacaggg
    22741 acaaacattt gattatcatt ggaaccacaa atatattctc ctgttttttt accatatcca
    22801 attcctttcc ctagcaaaat aaattcatta tcctttgtgt catgaactaa aacaacgctc
    22861 gagttcaaaa ctttctttat tatgtagttc attttatttg ctcaccttct attggtcatt
    22921 taaaatctat actattactt tcaattacct ttttatacca ataaaaacta tctttcttat
    22981 atcgattata tgtccccttt ccataatcat cagcatccac ataaatatat ccataacgtt
    23041 ttgacatttg tttcgttgat tcactgacca aatcaataca accccatgaa gtgtatcccc
    23101 aaagttcaac accatcttca ataatcgcat ctaacataca tttaaagtgt tcttttaaat
    23161 aattaattct atattggtca tgaacttttt tatcttcagt taaaatatct ttagctccca
    23221 atccattttc aactataaat aaaggctttc tgtatctatc atataattca atcaaagata
    23281 tacgtagacc tattgaatca atttgccaac cccattcact catttctaaa taaggatttt
    23341 ttacagctaa taacgtattc ccaggtgtaa tatctaatcc agttgtatca gctgcctcac
    23401 aagaagacat atagtaagag aatgaaataa aatctactgg atactttttc ataatttcat
    23461 catcatgttc ttcttttact atttgaatgt tattattttt aaaatacgac agtaaatata
    23521 ctggatactc accaaaaacc tgcgtatcac tatatgcata aatacttctc attttttgtt
    23581 gagttgccaa aacatcttct ggtctacatg tgtatggata atacgttaat tttgttaaca
    23641 tacaccctac ttttgaattt ggaataattt catgacaaat ttttgttgca agggcactag
    23701 ctacaaattg atgatgcata gcttgaaaaa taacttcctc aaagttttta tccttaaaac
    23761 ggtctcgaac taaaccacca gtagtgtacg gatgacgaat catagaatca acttcattaa
    23821 atgtaagcca atatttcact ttgtttttat atctttcaca gatagtttct acatacctaa
    23881 caaacatatt gataacttgt cgtgaatacc atccatcata gtttaaaacg atatttaatg
    23941 gtggttcata atgtgacata gtaacaagtg gttcaattcc ataacttatc aactcatcaa
    24001 atacatcatc ataaaactgt aaaccttctt catttggctc tttatcatct ccatttggaa
    24061 aaatacgaga ccaagcaata ctcattcgat atgtcttaaa tcccatttct gccattagag
    24121 caatatcttc tttatagtga tgataaaaat cactaccatg acgttttgga taatttactt
    24181 catcttcagg atgtgctaat ccttcttcta tatcttttgt tgtgatttca ttattagatt
    24241 tataatcttt cacatctgca tcaaagtgtg cctttgctac atctgataca gaccaccctt
    24301 tcccacctaa attccaacca ccttcaaatt gattagcagc tgtagctcct ccccaaagaa
    24361 atccttctgg aaactttctc atatttatat tcctcccttt acatcaaaca agatacttcc
    24421 tttttttaca ttgccataag actggtttaa cactttataa gcataatctg ctccattatt
    24481 gtttacaatc ataacagttg aatctaaatt agcatgtgag attttgtcta aatcaaattg
    24541 aattaataaa tctccttctt ttacattatc gcctgtctta acaaatgttt taaatccatc
    24601 tccattcata cttacagtat ttattccaat atgaatcaaa atctcagccc cattttttgt
    24661 tcttaaacca attgcatgtt ttgtttcaaa taacatcaca acttctgaat cacaaggtgc
    24721 gtataaattt ccattggtcg gtataattgc aactccatct cccaaagtct tacttgcaaa
    24781 tagttcatca ttaaccttac ttaaatctat tacttttcct tctactggag ttactaagat
    24841 atttacttct ttttcttctt ctagctcttc ttcaacaaca tctccaattg atgactctac
    24901 tgtatttgta tcttccttcc aaataatcag tgtaataata aacgagccta atattgcaat
    24961 aacaaaacca atacttgcaa aaatcaaatt gtttccattg tttgggtcaa taaacatact
    25021 catactggca agccctggtc caacaattac aaatcctttt actgcaaata atcctaaaaa
    25081 tgtaccagaa attgcacttg agaatacaac acctaacatt gctcttttat gttgtaaagt
    25141 aataccatat aaagctggct ctgtaattcc catcaaggca gaaattcctg cagataatgc
    25201 tgtttgtttt aatgtttcat cttttgttcg caaggctact gcaaaacaag caccactttc
    25261 agaaatattg tgggctaatg aagatgtcat atataaagct tcataaccca actttccaat
    25321 tgtattaatt gaataaggta ttagtgcttt gtgcattcct gttgcaacca taaatggaag
    25381 aaaagcagca agtaatccta caactaagaa tcccattttg ttatataaga ataaaataat
    25441 ggttgtaaaa attgtaccaa cgttatatcc taaaggacct aaaatagtta gagtaattgg
    25501 aacagtaatt gccaaagaca tcataggaac aaagaaagtt cgaattggtt ttggtgaata
    25561 cttgttaaaa attttctcca ttgttgccaa gaaagacaca cataagatag ctgggaaaac
    25621 ctgtgcatta taggcaatgt ttggaattgt aaatccaaat agttcgacac cttcacttaa
    25681 agcagttgtt gttgctggaa gcaataagta tcctacagcg gcaatagcta ctaaacgatt
    25741 acatttcaat acattggcag tagttacagc taccataaga ggtaggaaat agaatgttgc
    25801 atctgaaata gcaactaata atgtatatat agtagaatct gattttaaaa tattaaacat
    25861 tgctaataac atcaacagtg attttaaaat accagctcct gcaatagcaa aaatcagtgg
    25921 ttgaaaaata ttaataataa attctataaa tctttttcct aagtttattt tttcttcagt
    25981 ttttacagta ctatcatttg tatctaaagg gcaaactttt aaaatttcat catacacatc
    26041 aacaacacta ttcccaatga caacttgaaa ttgtgcccca ttaactatac tcataacacc
    26101 ttgtactttt tttaaagcat cctgattgac tttacttcta tcaatcaact taaagcgtag
    26161 tctagttgaa cagtgttcta aagctaaaat attttttgaa ccaccaactt gttcaataat
    26221 gtcaatggca gtttttttat aattcatctt gtaatctcct tctccataat tttttatgaa
    26281 tggccattca agatgcaaaa aaggcagaac ctatataaac accttgaaaa atcaaagcaa
    26341 tatattcgat cctgcctgca ttaccagtaa catgtcttct atttatacta ttttgtatta
    26401 ttatattaac atttgcctaa aagaattgtc aatacttttt taaattttct gatactaact
    26461 aatagcacct ttataattca ttttttatgt caattaaagt aacagtagcc acccaccaat
    26521 tagtatcaaa attgaacctg gtattttttc ttttatattt tctttgaata taaaatgagc
    26581 aagtattaaa gttattatca tagatacttg agaaaatggc tctgctatac taagttctag
    26641 attatttaaa gcaattaata atgctaaata agaatatcca ttaatagcac cacttaaaat
    26701 tgaaagcccc tttttattag taaaaatctc acaaattatt ttttgtttct ttttaaatga
    26761 taaaaagata aataaattta aacctacgaa aaaatacagt atagttgaat ataatatagg
    26821 agatacttgt acaaaaaaag ccttatccaa tactcttcct actgactgca aaaatatgta
    26881 taaaaacatt aatctacatg gtaaattgtt aaaaattaca gaaacattct ttaaaaaaga
    26941 gcttactttt tttaatataa acactccacc aatcataatt atgattcctg caacttttgc
    27001 taaacttaaa ccttcaccta aaaatataac tgataaaagc agtaaaaaca atgaatttaa
    27061 actatttatt ggagtaacaa gtgaaacttc cccagttgct aaagacgtta catacgctac
    27121 tgaaccaatt gaatagacta aactacttat ataacatggt attaaaaacg accaatcact
    27181 aactctatcc attatgctaa atggaagtaa acatactccc cctataaaga aaaatagaaa
    27241 tgatgaagct atatttttat aaatatctcc ttcttcatca cctaataatc ttacaactac
    27301 tctttcaaaa gctaatagca ctactctaat taataatgca aaataagata atatcatttt
    27361 tgacctcgct taaaaattaa tccgacttat tgttatatta actgtataag actaccatat
    27421 aggtaagtct tttggatttt ttaatatttt atgtttaaat acaggtacat taagtttttc
    27481 acctagttta cggcattgct ctttataggt accttttaat ttatcatgaa aaactataca
    27541 atcaattcct ccttcaatac tatttataca cttttctagt ttctcaaatc cagattcatc
    27601 atcatacatt ccacttacaa tccattgatt tggcaataca tgtccaattg atatgttata
    27661 ttctttattt tttataatat ctgagaaaga tttctcaaaa tgtacccctc caacacataa
    27721 caaagtcttc aaaggttcat cacaatcaaa tactctaatt aatgattttg ccaatacctg
    27781 tattgctata ctattattaa aactatcact actacttcct atctcaatat ccaacatagg
    27841 tacagaatat tctgtaatta atttagattc ttcaccatat gttgttccag accagtgagt
    27901 tgcttctgtt aatgtagtaa attcatcaag tagattttca ttttttatat cctcaatagc
    27961 attgattaga tttttaaagt atcttggatt tgaatttcca aattctcctg ttggaacatc
    28021 tccaattgta tgagctgtta ggatatgttc tggagcattt tctccctcat gccaatttac
    28081 aactcctgca aaatcataat ctctaaaatg tctatttaaa attggaagat aatatttata
    28141 attatgactt attacatctt ttgtttttac aaaatgaaat aagttattgt ttttatcctt
    28201 aaactctaat acaaaattat catcaataac aatatcagtt tgatttaaat ccattatttc
    28261 ttcacaacat tttatcacat tactggctac tgggtctttc tttaaatcac tgcaaaagaa
    28321 aaaaactgct tttttattat tcatccataa atcacactcc tataacttaa atataatata
    28381 tcttcatacc taaaatcatc taaatatcac tctaattcca ttaaattatt tatatataat
    28441 atactaccat actcatttta gctatacctt tgcctgagtt tctatatata tgtgatacat
    28501 cagctttaaa tcttatagaa tttccactag atacaatgta atcttctcca tttattttaa
    28561 tggttacttc gccactaaaa acagttataa actcttgtgt tcctggaagt tcagcatttg
    28621 aatctaaatt tccaccttct tctatttcaa tcataaatat ctcaaatctt cttttggagt
    28681 caaatggaaa tattggataa cttatatact ttccattatc ttcaataaaa tggtctatat
    28741 cacttttttg aatcaattct atgtcacttt cctgcctctc catcaatgat gtaaatgaga
    28801 tttttagccc attagttatt ttcttcaaag tagatatagt aggatttacc tcacactttt
    28861 caatttgaga tagcatactc ttacttacac cactaagttg tgcaatcttg tctaaactaa
    28921 gatgtttttc tttccttatc ttttttaaat tttcagcaat tatttcattt aaactttgca
    28981 taaatacccc ctaatacata ctaatataag ataaattatt ttgattatta aataaactta
    29041 gtaatttaat agaaactttt tatccattat aatgtacatt atgtttaata tacattactt
    29101 tttttagaat gtaaatagtt ttctgaaatt ttgtgaaaat gaataaataa aaaactagta
    29161 acctatattt ttacaaggtt actagctttt attataataa tctttcattt taactataaa
    29221 acttagatgc acctataagc tgtctcttag aaacaatctt agctaggttt gctaatgaag
    29281 aaatttttat atctttaaaa gaaactaaaa atacaaactt aaaatctgta aattcttgat
    29341 ttatattgta tatatcaaaa taacatctca aattatcaaa taagtaatta tcctgtaagt
    29401 ctgcttctat ctcatcagta gcatctttta aatacgctct tacatcttca aataaaacac
    29461 tgaaataaga ctcatctatt tcttcaccta actcttccaa tatttcttct atatctaaat
    29521 catccatatc aaaagaattt cctgtcaact ggcaatcaaa taccaatata ttttcttgat
    29581 ttatagtatt tgatatatct tgtacatatt cgaagtctgg acgtaattct aaaatgtctt
    29641 ttatttcact gctctttaca tggatttttc cttttctatt ttcaattttt aaatctatca
    29701 tatgctcccc ctttcaatct acaaatcttt aaataccttg ttttataatc ttttcaatat
    29761 ctatccaatt actaactcta actatatttt gatgtttaac atctttatta tagttagtat
    29821 ccagaagtat tactttaaca ccatcatcag ctagttgcac tgagtttaaa ggattatctt
    29881 ctataaatat gtcacaactc agttctcttg ccttttcaac tttataatca cttcctaata
    29941 agtaaacatc tatatctgaa aatccttgtc tcgatagcca atttttagtt acatcagtta
    30001 aacactcatg tctagccgtt acaaaagata aattatgtcc tttagataat gtgctaatta
    30061 cctctgtagc accctctaca atctttgctt catcatatga gtgtatatac ttattattaa
    30121 actccgcata cacatctctt attcccgaac catacaattc ttcccaatta tgtgttatac
    30181 actctgcttc agttatattt ttattaaaga tatcatttag gtatggaaga aaatgataag
    30241 ggcttgttat tgttccatct atatcaatac atatattcaa tttgttcatt tttacctcca
    30301 tgtaacattt attgatttga ttaatcaaat attatagcac agctttaatt ataaatcaaa
    30361 actctggata tgactatacc tatataatac caaaaagctt gcatatttaa gcaagctttt
    30421 cgtaaatttt acatttttaa ctaatatata agtttttcta aggttggttc cactccaaat
    30481 tgtgatttca gttctttata ttcttttaat gctttgtcat tattcgtttt agtttttatc
    30541 gctcttatca ttaaattttt tggtgtatca agtggagata tgtattctac tacagaagta
    30601 tcatatccat tgccctccaa taacaatgtt cttaaaccat cagttattaa atctgcaaat
    30661 ctagctttaa atacaccatg ttttaatatt ggttccatag cttcatatct atattgccct
    30721 aataactcct tatgacaaca tggtactact actatagctt cagattttgc tctaattcct
    30781 agacctattg ccatatctgt agctgtatca caagcatgta gacttattac aaggtcaaca
    30841 tccctattag gtgtataatt agtcaaatcc tcttttataa atgacatatt tttataaccc
    30901 aagtttttag ccatattttt tgatgcttct ataactacat ctgaataatc tattcctata
    30961 aaataacagt ttttcttcaa tacttctttt atataaaaat ttaagacaaa gcttaagtaa
    31021 gattttccac aagcacaatc caagatagtt atacagtctt tatcctttat ttcttttaaa
    31081 atactatcta tcaattcaac aaaatggtct atctgattgt attttcttat tttatcattt
    31141 tttatcttac catcttttgt aagtactcca atttctttta aaagtgcatt tgcttgtcct
    31201 acttttacat aataatctct gttttttatt tgagatgccg taaattcatc tattttaggt
    31261 acttcttcct tattatctaa atattttaca tttaccttct tattgtctcc ttcaattaca
    31321 acaatagttc ctcgctcaac atatttaaat actaatccat cataattttc tgcctcttta
    31381 gaaatattct taagcaactc attaaacgta tataaatctg attttccttt aaaattaaat
    31441 ttatatttat tatcttcctc tattgcaatt cctttaaact cttttcttcc agatttaaaa
    31501 atcacctcta actcaataaa aaaatcccta ttatcaaggt ttctttgagt aatccccata
    31561 aaaaacatat ttagttttcc tatactctgt ttattcatca taatctccct tttaacttat
    31621 atctttaaat cttattaatt aatattattt gtttctgaat tatttatttc ttcttttaaa
    31681 tcgttcaatc tatttttaaa actttctatc tgcttatctg ataaatcaag atattctgtt
    31741 atcttcccta tatatttagg gcttttagta cttattaatt tcaaagcact ttccatagat
    31801 ttttctctaa gctcatatgc tttctttacg tcatctctag cattactcaa tgtttctgta
    31861 tacttctcct tagaaagttc tggaatctgc atattttcat attcttttac aacttcttta
    31921 cacttgtttc tggcatttgt aacatctttt tttatactag ataatttagt tatatttttt
    31981 gctatatcct tagtgtaagg tatacattct ctcattggaa ctaaagctgc tctttctata
    32041 ttataaattt ctttcttaaa aattcctata ctttccatat ctattttttt tatatcttca
    32101 ctattttttt ctttacttgt atatttatta ttttcttttg tattatcttc ttgtttttct
    32161 gatttattat tcactgaaac attactatca gaattattct tttcttttat atcattactt
    32221 ccttcttcat tactttcttt attttgtata tttctatctt gtttgttgtt taaattttta
    32281 ttatttgata tttcttcatt ctttttatta tcctgtttta aatcagtact ttctttttcc
    32341 ttaaaatttg atacatactt ttcatcatat gtctcatcag aaatataatt gtgataatac
    32401 atagactctt ttattttatt aagtccactc atataaatat tacttatcat tattgttgta
    32461 gctaatacca cataaatact actgtagata caagacctct taaaattctt gtaatttctg
    32521 aatatcacta ctaaaggaat aagatataaa aatataaaaa ctaatatcca cctcataagt
    32581 cgtgtctcct ttctcaaaac cgaaatccct caaatattta tttttaatca tgtatcttat
    32641 agtatttacc aatttatgtt ttttaatcgt gaacttttat taaattaaat tctgtatagt
    32701 cacaagatgc taatgtatat tctactccat ttcgaatccc cttcaatccc attttaaaag
    32761 attctttacc atgcaagtga ccataaatca ccttttcaac attatattct tcaaataact
    32821 ttgtaaataa agattcttcc aatttatcat tcgtaggagg ataatgagta atcacaatta
    32881 tttttgagtg accactttta cgagcagatt ctaatgatag tctaagtcta tgctcttctc
    32941 ttttataaac tttttcatca gtctcatcaa atttgacatc attaggacat atccagcccc
    33001 tacctccaca aattgcataa tctttatatt cataaaaatt tgtctgaata aaacgcatgt
    33061 cttcatatag cttatttaaa cttgtaacgg ttgtccacca gtaatcatga tttcctttta
    33121 taagtatttt ctgacctgga agtttgctta ttatatctaa atctttttta gcttccgata
    33181 aattaattcc ccaagatgta tctcctagta ctaagaccat atcttcttcc ttaacaactt
    33241 ctttccaatt atctataatt ttcttttcat gaccatccca attacttcca aagatattca
    33301 ttggcttatt gactgatgtt gaaaaatgta aatcacctat agcatacaaa ctcataatat
    33361 cattcctttc ttaattacac taaataggct gtctcttttt agaaattatt ttccattaag
    33421 aggcagcccc attaatattt agcaaatttt ctacaagtag ttttactgaa ctactttatc
    33481 atctacctta gtatccttat attgctctaa taatatatct atttcttgtt ttaattccaa
    33541 aatttcagtt atatttttat ctgtttcagt tctatcaagt tttctttggt actgcatagc
    33601 tttatgtgta tcacccaagt catataactc ttgtattcta tttagagtat ctctaatagc
    33661 tatagacttc atttggtaca tagcctgagc tttcattatg tcctctctta tttcactcat
    33721 ttcttggtct aaaagaaagg cagcatcaga tgctcttcta agcctttcag caagagtctc
    33781 aggtatgtaa tggtcatatt tatattttaa tgaatgttct attgtagccc agaaattcat
    33841 tgcaagagtt cttatttgta tttcacatat aatttccttt gaacccgcaa tggagtttat
    33901 agggtatttt attataacat gatagcttct ataaccacta tctttgtaat ttgtaatata
    33961 atctttttct cctattatag tcatatcatt tcttactttt atcaaatcaa ctatagcata
    34021 tatatcctca acaaactggc acattattct tataccagca atatcatcaa tttcagtttc
    34081 tatatctttt gcatttatcc tttttaactt agatattatg gaagatattt tttttgttct
    34141 acctgtgaca aactctatgg gagaatattc accttttgct aaatattctt ttcttatatt
    34201 tttaaatttt attttcaatt cctctactgc atgttcataa ggtgctagta tctcattcca
    34261 tttttcgtat tccatattgc tcacccttta tttgtttttt atgaccttct ttattttatc
    34321 ataatttatt ttgtttttgt atagtaaagc aattctccat tttccaatat ataccctatt
    34381 tcttctaaat caactaagta acttatgaca gatactaacg aagatttaaa aaaatgatac
    34441 tctttataat tattgcttaa attattgtta tttataatgt tttttaataa aatttctaaa
    34501 gatttcggtt ctacaagcaa ctctcttatt tgatataaat atttttttaa agcattcaaa
    34561 tgtttttcta ttaatttata agaatcttct ttcgatataa cttgcttgcc atgccctaaa
    34621 actaagtact caaaatctat attttttaat ttttctaatg aagttatttg ttcttgtata
    34681 tcatatagaa acaagaaatc gtattttgat aaaatttcat ctcctatcaa taaatcgcca
    34741 acaaaaatca cattatcctt cgtcaaaaca gctatactac caggtgtatg accctgaaat
    34801 tcaattatat caaacatttc attgtttaat tcaatttttc cagcttctat agatttatct
    34861 atttttatat catccaacat tttatttttt aagatattat ccataaatac attgctcttt
    34921 cccccaacaa tatactttga aaacaattct ggattttcta tatataattt atcgtattca
    34981 gatgacatta tacacacatc tttataatat tctttaaatt gattacaagc tccatagtgg
    35041 tcatcatgac catgagtatt tataatatat ctaacctgta tattattttc atctaatact
    35101 ttatttactc tcctaggtct tgaaccacat aaccctgggt ctatcataag tgctgtgtta
    35161 tcttcaaata catatattcc tgtattcgtg ccacctttta taaaaaaggt atttcctttt
    35221 acttttgtaa gattcacctt cttcacctca ttttgacaat atttatgata caatttatta
    35281 cttactaata taaaactata caagaacaat cctttttatt ctatctatag ttctttttct
    35341 tattttgtat tctttagata tccttatttt cacattatat gctaaatttc tataaagtaa
    35401 tgactctata aaatattcaa ctatacctct atccctaaag tctatatcta tatttccact
    35461 tgaataaata tttgagtcta atatcataag ctcatcaaaa aagcttaatc tcttagattt
    35521 acttaaataa tctttatttg gaataaatct atcacaataa tctatcctgt aatttactac
    35581 ttcatcattt atttcaaatc catattgctt tttcattaac tctctatagt tattattttt
    35641 ctcaataaca ttatctaaat ttttattata atcctctttt ttccaatgtc caaacatcct
    35701 acaatttaat ggtctaactt catatattaa acatctatta ttagtatctt taaatggaca
    35761 tgggttcttt cttgtatact cctcaaaata ataatctaat attttactta tacagctttt
    35821 ttttaaatca actctatctt caagataaca aaatatattc aaaaactcaa ttaaatttat
    35881 acctactgac tccatacaac aatttccaca tccagaacaa tttcctactg gcaaggactt
    35941 atatacatca tttagtttgt caaagagctt atttttaatg gaataatcta tacaatttaa
    36001 aatatcttta ttttttatac tagtcattat tattactcct tgttataatt attaagttaa
    36061 tacaaacaat tattataaca tattttttaa atttaatcgc atatggaggt attttatgaa
    36121 tagatataca aaaataatta atatgatggg aagttattac acaaaagact ttgaaaaaga
    36181 aaaaaagaat gtaataaaag ttagagaagt taaagaagat acagttagaa aatttttctt
    36241 acaaggtgac tgtgaagttc ttgtagtatt tgaagacact gggaaagaaa tacttattga
    36301 tgacttttct cctgaagaag atatcaaaaa atatttagga gcaaaattta taaataaaaa
    36361 aagatagtta tcaaaaataa ttctaaaatt aaaatttaat aaatgtacag ttataattct
    36421 atataattat agttaaaagt tatcttttat tgctttttta gactttaaga tagctttttt
    36481 tctatttttt gtaaaataat tccataattc acattaataa ttcacaaaat gatataatat
    36541 aacaaataga taaattttaa atttctaaat acataattaa tattttgcga ggtgatttta
    36601 tgcaaattta ttttagagtt aaggctgttg gcaaacgcaa acctatgcta gaacttaccc
    36661 cttttgatgt acctgacaac atcaattgcc taaaagaagc tatctctgaa attgtatcta
    36721 aaaatgttct tgaatataat gagaaaatcc cagaaaaatc aataataaac ttcttaacta
    36781 atgaagaaat tgaatctcaa gctgatattg gaaaagttgg atttggctct atttacaatg
    36841 agaataaaca atctgtagaa aaggcaatag aagtagcgtt acaggcattt gaagatggaa
    36901 tctacaaagt gcttataaat gaagatgtta ttgaaaaact cgattcctct ataaatctga
    36961 aaagtggaga tatatttact tttataagac ttaccttgct tgctggaaga atgttttaaa
    37021 ataaataatt tggaggtaca taaatgttag aacgtactag agtagaaaaa aatcctaaaa
    37081 taattgaaaa ttttaaaaat aattttacta aatcttcttc aaaacagtac tacgacttag
    37141 caaagtctct ttgggactgc atagaaaata gttcatacta ttatagagaa cctgaagaca
    37201 aattcttaaa tatgataaag aaatactaca attgccacta ctacgaaatt aaaaatatgg
    37261 acgagctcct ttctggacct ttaaaaaatg cattagaatt aatatttact tctgaacaag
    37321 tagaagaact ttgccaatta attaaaagaa agatggatta tacatattca ggaggatatt
    37381 atcgtaaagg gtatcgctca aataaacttg tggattattt tagaggtatt ataaggttta
    37441 tttcaaacta tgttgattta atttattatg atttttcagt tatagattat cttactcttc
    37501 caaataaggt cttgtactat gactctataa tgagtgataa aatagcacta gaaatagaca
    37561 aaggaaatca aaaagtaata agtgctttag aagaagtaat atttggagaa aatcaaactg
    37621 ctctacttac aagacaaatg ataattggta tcatgaagag tcatagtgat aaatgctatg
    37681 aaatgctttc taaacttctt ttggcagcca aacaacaaga aggacttaga cagcaaattg
    37741 tagagagttt agatgagggt acaatttctg catcaatata catgttaaaa actattttgg
    37801 acaacaattt agagcgattt agttctgtta taagagcctt ggatacatgg acaggacttg
    37861 gtttttcaga ccaaaaacct ggaataatac gtaaatgttt agaactttca tataaatcat
    37921 tgactgatga aaagttccgt atagaatcaa ttaatagcaa tgataatctt gaaatttatt
    37981 ttgccttgtg ggctactgca acttacaaca tatatgactc ttactctctt attgaaaact
    38041 tactttcttg tcaggaaaaa tataaaaaac ttgtagctct ttacttttta tcgcatacag
    38101 aaagtacata ttttaaacat tctatagcat ctaaaaacat taagggtgat gatttagaga
    38161 tactagcatg ggtaattaca aatttctatg tagaaggttc tgttggctac tactatagtt
    38221 ggcaaaacag agaaactaat tttgacttgt caaacactcc tattgacaaa gactttgatg
    38281 ctagaaaaga acaatttgaa agtttaaaac atactttaga aattttaaat tcaaagacaa
    38341 aatcattttc aggaagtgta tttccatgga cttggattga aatttcttct catgaaatac
    38401 ttaaatgtat gatgacttta acagcatacg atatgaatgc tcaatttata gatgtgctta
    38461 tggaaaattg tcatcttatg agttcagatt taagagcttc acttatagtc aattttgtaa
    38521 atgaaccaaa gacagataga caacgtgaat ttttattgga atgtttaagt gataagagtg
    38581 tttccaatag agaaacggta ttgagtctac ttagaaagct tgagctaaca gatgtagaat
    38641 tagataagat aaccaatcta ttgtctttaa agacaagctc tattagacaa acagtaataa
    38701 aaattttact tgaacaagat gattcaaatt tggaaaatat tgcttcttca ctgataaaat
    38761 cttcaaattc tcaaaaatgc cttggaggtc ttgaaattgt aaacttatta aaagacaata
    38821 ctgctagaca agaactatat aataagctta ttttacttat agaggatatt gataaatcta
    38881 aaaagaatac atctcaagtt caaatactaa ttgataattt gttaggtaaa gcaaaaaatg
    38941 attactgcaa agaaaatggt tttggaatat ataaccctga aaacaaagtt caaattccag
    39001 aacaatttga ttttaaagat gattctaata gctcatcaaa gcttaataaa attatctcaa
    39061 atataagttt atctactcgt gaggattctg tttctgtagc aacaaaaaaa gaagcaaaaa
    39121 aaattctcga tacggatata aataaaataa taaaagttta tgaaaaattt gatgaactta
    39181 ttactgaaaa tgcagattat gaatatgaag ttgaaagatg gtcaggtaat gtagacaaag
    39241 tacttttagg ttattctact tataacttga ctcctattaa atataaagtt tctaatgata
    39301 ctcttgataa ttatccatta gcagagcttt ggagagaaac tagtaaaaaa cttgacttag
    39361 attacaaatt aatacttgat atcttatttt atagtataag tacatgtgga tataatgaaa
    39421 cagaaaaaag ttggttttca tctatatatt caaatgtcct tgactctaaa aaacaaaata
    39481 aaatatatac aaaacttgaa aaacttaaat ttaatggact tacaagaaaa cttttaagag
    39541 ttttactaaa tgagtttgac cataaagaaa tatttaacta ttgtttagaa atatactata
    39601 aacttagaaa cttattgact atagaacaat gtaaaaaaca aagagttgaa tttactaaaa
    39661 actattacag acaaaatgaa tactgccctg ctttaaatgc ccctatttta aactattggc
    39721 ttgataaagc acattcgttt atttatgatg atatttcttt tactaagttt ttctacacta
    39781 cgttttcaaa ttatcagttg ctagaatata agtttccttt ctatactagc ataaatgtgt
    39841 ttgctcgtgc acatgaatta ggattaatga ctgaagagca agttaataga gaaatgataa
    39901 gtggatacaa cgcatcaaat ataataagaa cattgacaaa tcctagatgg gctggcgaca
    39961 cattagaaaa gtacccttgg cttaaagata atttaaaaac tgttacaaac cgaattatag
    40021 aaattgaatc acgtagaggt gatatgccaa cagaagtgtc taatctagct aataatatac
    40081 aatactttga aggtataaat tattttgtaa atattttggt cgctcttggt aaagaaactt
    40141 tccagagagg atattcatat ggtagcaatt attcaaaaaa agatgtttta agttctctac
    40201 ttaaaaattg ctatcctact aaagaagatg attcaaaaaa attaaaaagt ttacttaaaa
    40261 ataccgacat tactgagtta agattgatag aatctgctat gtatgcccct caatgggtaa
    40321 acataattga aaaatattta aactggaagg gtctgaaaag tacaatttgg tacttccatg
    40381 cacatataaa tgaaggcttc tctgcacaaa aagaatcaga ggttgctcta ttctccccta
    40441 tttcaccacg tagtttcatt gatggtgcat ttgatgtaga ttggttttta gattcatata
    40501 aaactattgg ggaagaaaga ttcaatatac tttacaagtc agctaaatat ataactagtg
    40561 gtggtaactc tcatagacgt gcacaactct atgctgatgc tacacttggt aagcttgata
    40621 aagacatgtt gatgaaagaa attgaaacaa atagaaatca agataaattg agaagtttct
    40681 ctttacttcc tatgaaaaaa ggagacctaa aagaagcaac tttccgttat gaatttattc
    40741 aaaagtttgc taaagaaagc aagcaatttg gtgcacaacg tcgtgaaagt gaatcaaaag
    40801 cttgtactat agcgctagaa aatctagcta gaagtgctgg atttggagat gtaaatcgta
    40861 tgatgtgggc tcttgagact gaaaaactaa atgaagttgc tcatctattt aaaccaaaag
    40921 atattgatgg tacttcaatt tggatagatg ttgatgaaaa cggaaaagca tctactaaag
    40981 ttcaaaaagg caacaagtct ttaaagagta taccaaaagc tattgctaaa catccatatg
    41041 tacttgaact taaatctgtc caaaaagatt taaagagtca gtattctcgt gcaaaacaga
    41101 gtttagaaca agctatgaaa aatgaaatag tatttacagt taaagaaatt gccaatatct
    41161 ataaaaatcc agttatctgc cctttgatta aaaatctagt atgggtatgt gatgataata
    41221 ttggatatgt ttataatgat aagtctaagt tctttatttg caatatagaa ggtgaaactt
    41281 ataagttgac ggcaaaaaat aaattaaaac ttgcacatcc agttcatttg tttgaatctg
    41341 gtaagtggag tgagttccaa catgatttat ttagtaagca aattgttcaa ccatttaagc
    41401 aagtattccg tgagtattat agaataaaca gtgatgaatt atctgaaaaa actatatctc
    41461 gcagatatgc tggtcaccaa attcagccaa agaaaactgt agcacttctt agaaatcagc
    41521 tttggactgt cgattatgaa gagggattac agaaagtatt ttataaagaa aatatagtgg
    41581 caaagatgtt tgcacttgca gattggtttt caccagcaga tatagagcct cctactattg
    41641 aaacagtaga attttttgat agaaaaactt ataaaagttt agaattagct tctatacctc
    41701 caattctatt ctcagaagtt atgcgtgata tagaccttgt tgtaagtgtc gctcatgctg
    41761 gtggtgttga ccctgaaact agccattcta ctgtagagat gcgtatagca attgctaaag
    41821 aacttttatt attattaaaa attaacaatg tcaattttga aggctctcat gctcttatag
    41881 caggtaattt aggtgagtat tctgtgcata tgggttctgg tattgtacat aaaaaaggga
    41941 tgggtgcttt gaatatactt cctatacatt ctcaaagtag aggtaagata ttccttccat
    42001 tcgctgatga agaccctaaa actgctgaga ttatgtctaa gatactatta cttgctgaag
    42061 atagtaagat taaagaccct agtatcttaa gtaatttata agtataaaaa ctatccctaa
    42121 aatatattgg actttcttaa aaaaaattag aaagtccaat atatactata ctgtaattta
    42181 tatagattaa atcataatta caaataattt ttatataaac ttctcttata cattatcttt
    42241 atggtactta ttatatcaca caaaaagtat ttttcttcta tcttcactag aatcttttaa
    42301 ccctataaaa tctatataaa aaatcttttt ctagagattt gtttaatatg gcattttctt
    42361 gaaaatttat aaaccttatc tctaatgaag atttatttat aggtataacc ttatgtataa
    42421 atcttagatt tactatgtat tgtctatggg tcataaagaa attaggaggt aggcgttttt
    42481 ttaaatcatc aaagttctca taaaacttta ttatatcttc atctttagtg tgtagattaa
    42541 ttgctcttga atttttctca aacataacta tatcatcaaa attaatcata tgtatctgct
    42601 tccttatttt atatacaaaa agggtgtctt ctataaaatt attattagca atcttatggg
    42661 agttaatatg gtctattgct atgttaattg aatcaagtat tttttctttt ttaaatggtt
    42721 taactacaaa atctatagga tgcactttaa agctttcaag actataatca gcgaaacccg
    42781 tcacaaatac tatatgtata tccttatcta tagaaagaat ttcttcagca gaatcaatcc
    42841 catttttata tggcatatca atgtcaataa tcaataaatc tattttctca ttttttataa
    42901 attcaattgc ctctatacca tccttaactt ttttaacata atctacatat ccagactctt
    42961 tagctatatt tgctatatca tctcttacaa tcttatcatc atcacaaatc aaaactttta
    43021 tcatagactt ttctcctcct aactaataat attttgggat taagattaca aattcagtta
    43081 aaaaatcatc actatttaca agtatactat aatcatactt atctaatata tttttaacta
    43141 aatgtagccc atatccccta tcttgtcctt ctttagtact aaatccattc caaaatatac
    43201 tttcaacatt atgtatttta ggaccattat tttttatagc tataatatac tgaaattcat
    43261 cttcatatgc atgtaatctt atatacttct tttctttttt tatagtagac aaagactcta
    43321 ttgcattatc tattatgttt aatagtactg aactcatatc attaggttca atctctaaat
    43381 tatccataaa atcttgaatg tagacatcaa aagatatatc cttttcaaga cattcctcgt
    43441 attttaatga agctatagca tctaaataag atacttttcc ataccttgaa ttttttgatt
    43501 taaagctatt tgatatattc attatatatt ctttggcatc ttcatctagc ccagtattta
    43561 atagagaata cactacttgc aaatgtttca aatagtcatg tttttgactt cttaatttga
    43621 taattatatt atccttatga tttattttac tatctagttt ttgtaattta tattcctgtt
    43681 cattattatt atttatcaat cttataactt taaagcctgt ataaaaactt aaaataatta
    43741 aaaccaaaaa aagtataata tttaatactc cttcaagtaa aaaactatat cctaacctta
    43801 attgtatata tttagtgccc tccataaata aaatcaatgc aaaacacgat ataaaaaatg
    43861 ttaatatgcc tctttttaat atgtctaatt ctttgtaaaa tttatactta ttcattataa
    43921 gattgctaaa tataaacaaa gttagtatta ctataggaaa tacaaaattg ttatccatga
    43981 ttcccctccc ctctacaatt tatataggga ttatatcatt ttaaaaaaat tatgtaaaaa
    44041 gttaaaattt acatatatat taattaaact tgtaaaaata cagatgaatt tgtacaatta
    44101 actacttaaa acttgaaaat acttactttg ctatatattt tagataaata tataattgat
    44161 ttagttaaga aaggaagtgg taaatatgaa agataatttg aaaatagtac taaggtatat
    44221 aaaaagttat aaagctaggt ctttagcaat tgttgtgagt ataattcttg ctacatcact
    44281 cgttgttggt attggtactc tctcaagaag tgctcagcaa gcagatgtag atagattgaa
    44341 aagagagctt ggagctgacc atgtatactt taaaaatata aagaaaaatc aattaaagtc
    44401 cataaaatct agcaaagata ttaaaaatct gggtataaca tcttactatg cgtctacaga
    44461 tgttaatgaa aaattaccta taaacatact atatacaaat aaaaattatt tgactagtca
    44521 ttctaaactt ataaaaggtc gatttccaaa agctagcaat gaggtggtag tcgagaaatg
    44581 gattttaaat agtatgggct taaaaccaga gataaatcaa aaccttactt ttaaattata
    44641 tcaaaaagaa aatccagaaa cttttaaagt tgttggaatc cttgaagata gatttataga
    44701 gaaaaaaaag ggacaatgtg aaattttttc taatctcaat gaatcagaac tgaatgattt
    44761 tacaacttat attgaattta atgaaggcag tgatataaat acaaacatag acaatataat
    44821 aaaaaatgct atgttagatg agaaaagtat aggaagaaac tcaatgctta tagaatctac
    44881 tatgaaaaac ggtactttag ataattcaag taaatacgtt gcaattgcta tgagtctatt
    44941 tgctggtatt gtaatatata gtatctatgt tatatcaata taccaaagag tacaggaata
    45001 tggcgtctta agagctattg gttccaccaa ctttaggatt ttcaaactta tgctttatga
    45061 acttttcata cttgctctaa tagcaatgcc tataggtata tgtataggta tgggaggtgc
    45121 acaaatattt aataggtctg taggaaatat tcaatttgaa ggaaatataa atgttacacc
    45181 ttttgttatt ccagataaaa taattctctt atcaattgca tgtacaatac taataatact
    45241 aattataagt ttctttacat acttaaaaat aagaagaatt tctcctattg atgctatcag
    45301 aaaaactttt ggagctgata aaaatgtaac caaagttaat tatttaatat caaaattaac
    45361 tttaaatatg tcagtaacaa aatctatatc tgcgaaaaac atctttagaa ataaaaaggg
    45421 gttcattata attgtattat ctatgagtat aggaggtata atcgtcataa aagacaatta
    45481 taaatattct tttttagatg tgcaaaacaa atctactcaa gaacaaacat atatgaatgc
    45541 agattttatt ctatcaaatg tttatctcaa tgaaattggt aacaatactt cttttaaaga
    45601 tataaaaggg tttaatgata atcagataga taaaataaaa aatatagatg gaattgacaa
    45661 agtcaaaact gctagtatct taaacacaag aatagaggta aataaaataa atagattaga
    45721 ttactacgaa gctataaatt caactcctta ttataagcta aatcctctgt tcataaaaaa
    45781 taagactact ggcaaatata cactaaagca aaagctaaaa ggttataatg atgagatgat
    45841 aaagtcatta gaaaaatact tagtaagtgg aaatataaac ttgaaaaaaa tgaaaaaaga
    45901 aaatttagct attgtatatg taccagaaat ttctaaaaca cagaaataca caaagacttt
    45961 tactcctggt gaagggacac cagctgtaga tataaaagta ggtgatacta taaaagtcaa
    46021 atatccaaag ggtgggatgg atacaggtct ttatgaaagt ctaaaagata attatgaata
    46081 cttagaatat gaatttaaag ttggagctat tataagttat ccttttgcag ataatggtat
    46141 gtactctgga gatgatggtg tagatgtaat aacgagtagc gaatacctaa aaaaattaac
    46201 tggtgtagat aagtataact tagtttatgc agaccttaat gaaaatgcaa acaagaaaaa
    46261 aataaataac cttttaggta aaattggaag tgaagttcct ggaactacaa cagtagatat
    46321 gatggtagaa aaagaaaatt ctgataagat gacatctaga actatgattt atagttatgg
    46381 tatagtagca ataatgttca taatcagtgt acttaacata ataaacaaca taagttataa
    46441 cttaacttca agaactagtg aatttggaat gttaagagct attggtatct ctgagagagg
    46501 ctttaaaaat atgatacttt atgaaggaat attatatggt gtactctcaa gtataattac
    46561 tatcgtgtca ggaattataa tacaatttaa aatgtattat atgcagggct ttgtatcata
    46621 tggattggga ttttcaatag attacaaaat atatatacta gttgttgtag caaatataat
    46681 tgtaggtatt ctagctacat atattccatc aagaaagata aataaaatta gtatagttga
    46741 agctataaac attacagaat aggaggaata attatgccta tattggaaac tattaactta
    46801 ggtaagattt atggaaaaaa ggaaacatct gtacatgcac taaagaatgc aaatttaaaa
    46861 ataaataaag gcgaatttgt tgctataatt ggaccaagtg gaagtgggaa aagtacattt
    46921 ctacatttag taggtggtct tgaaagacca agtaatggta ctataaaggt agatggtaaa
    46981 gatatatgtt gtctttcaga taaagaatta gcaagatata gaagacaaaa ggtaggattt
    47041 gtctttcaac agtataactt aattcctgta ttaaatgtaa aggaaaatat agaattacca
    47101 ctaaagttag acaataaaaa aatagataaa gaatatattg atgaccttat aaatttattg
    47161 ggtcttaatg aaaggaaaaa tcatcttccc aaccaattat ctggtggtca acagcaaaga
    47221 gttgctattg cacgtgcttt atctgcaaaa ccaagtataa tcctagcaga tgaaccaaca
    47281 ggaaatttgg acagtaaaac tacagaagaa gtcatggatt tactaaaaag ttctataaaa
    47341 aaatataacc aaacacttat aataataaca cataatgaaa atattgctag aaaagcagat
    47401 agaattatat ctataataga tggagagctt aaattaacac tctaaaacta tttatagaaa
    47461 agaggattta aatgttattg attttaggta atttaaattt aaacttggat tttgactaca
    47521 gaataataag agaagaaaat gaagatgtag atatatttat agatattaat tatcgtagct
    47581 tagatataga tactgatggt tctaacttat ttaattctag aatacaattt ccatttgtaa
    47641 gagcattgat tctaaggcta aataagaaca atcaatgtat gacaattcat ttgttaagag
    47701 atatagattt attctctgct tttgccaact ttgaagtgga ttatactgac tctataataa
    47761 atataaaaaa tcaaaatgag aaagtaattt taaataaatc tatcaaaaaa tagtaagggg
    47821 gccttaatag gccccaattt ttttcttttc taaacttatt atatcatgat aaataaatta
    47881 gtcaatagaa ttttctgaat atttttataa ttttttcata aagtttttta tatattatgc
    47941 tttaaaatta tatgtaataa aaaaattttc cgactaattt taaagttaat tgattaaata
    48001 cacatattcg aaattaccat taaattactg actttttatc atttccattt agaatttaag
    48061 ttataatcta ttatttatag ttacttctac gtgtctctaa taaaactcta tttatattca
    48121 aatctaataa tttatataca aacccaatag aacctatgtt gcacaataga tattatttac
    48181 cataataaac ttttagatat atctctttta attcactcat caatgggtat ctaggattag
    48241 cacctgtaca ttggtcatca aaagcttgtt caaccatagc atccaatctt tctaagaatt
    48301 tagattcttc tactccagcc tcttttatag tcttaggaag acctactttt gcctttagtt
    48361 catctattgc ttttataaga ttatctactt tttcttggtc tgtacttcct ttaatacctg
    48421 caaaagaagc aaattcagca tatctttgta tgcaatcagg atatctgtat tgtgagaatg
    48481 cacccatttt atttggagct tctgcacaat tgaacttgat tacttcattt attaataatg
    48541 catttgcaac accgtgttga acatggtgga atgcacctaa tttatgtgct aaagagtgac
    48601 atattcctaa gaaggcattt gcaaaagaca ttcctgccat agtagatgcc attgccattt
    48661 tttctcttgc ttctttatca ttctttccat ttttatatgc acgaggtaaa tattcaaata
    48721 ttattttacc tgcttgtagt gctagaccgt cagctggttc agttcttaac atagatacat
    48781 atgcttctaa tgcatgtgtt aaagcatcaa cacctgatgc tgctgttaat cttggtggca
    48841 tctccatcat catatcagca tcaattatag ccatgtttgg cattaattca taatctgcta
    48901 atgggtactt tacacctgaa tcttggtcag ttataactgc aaatggagtt acttctgaac
    48961 cagttcctgc tgaagttggg atagcagcaa aatacgcttt ttcacccatc ttaggaaata
    49021 catatactct ttttcttata tccataaatc tcatagctaa gtcttggaaa tctacttctg
    49081 gatgctcata cattacccac attatcttac cagcatccat tgcacttcct ccacctacag
    49141 ctattattaa atctggttgg aaatcagcca tagctttagc tccttctctt gcacaagcta
    49201 atgttgggtc tggagctaca tcaaagaatg tagtatgctt aattcccatc tcatctaata
    49261 aatcagttaa tttcttagta tatccattat tatataggaa agaatctgtt actataaatg
    49321 ctttcttttt atccataaca tccttaaatt ctcttgctgc tacacctaaa catccttttt
    49381 tgaaataaac cttttctggt gctctgaacc aaagcatatt ctctctcctt tcagctactg
    49441 tcttgatatt aagcaaatgt tttactccaa cgttttcaga tactgagttt ccaccccaag
    49501 aaccacaacc aagagtaaga gacggtgcca atttaaagtt atataaatca cctataccac
    49561 cttgtgatga tggagtatta actaatactc tacaagtctt catagcattt acaaactttt
    49621 ctactctctc tggatgattt atagagtctg catataatga agatgtatga ccatagcctc
    49681 catctgcaac taatttttct gctttagcaa ctgcatcttc aaaactttta gacttgtaca
    49741 ttgcaagtac aggagaaagt ttttcatgtg caaaaggttc atttaattca acagattcta
    49801 cttcaccaat tattattcta gctgtttttg gaacttctac atccgccatt ttggctatta
    49861 catgtgctgg ttgtccaact attctggcat ttaatgaacc atcaattatt actacttttc
    49921 ctactttttc agtttcttct ttatttagga aatgtgctcc acgatattta aattcttttt
    49981 taacttcttc atatattttt tctggtacta ttacagcttg ctcggaagca catatcatac
    50041 cattatcgaa tgattttgat actaagattg aacttacagc catttttata tctgcactct
    50101 catctattat tgcaggtaca tttccaggcc caactccgac agctggttta cctgaagagt
    50161 atgcagattt aaccattcca ggtccaccag tagctaatat aaggtctgcc tctgccatga
    50221 caacattagt taattcaatc gaaggaacat ctacccaacc tataagtcct tttggtgctc
    50281 ctgccttaac tgctgcatca tgtacaactc tagctgcttc tatagtacag tttttagctc
    50341 ttggatgagg agagaaaatt ataccatttc tagtttttag tgctattagg gatttgaata
    50401 ttgcagttga tgtaggatta gttgttggta taactgctga taaaacacct actggctcag
    50461 caattcttgt aaaaccaaat gcttcatctt tttctatgac accacaagtt ttagtatctt
    50521 tataagcatt atagatatat tctgaggcaa aatggttttt tataacctta tcttcaacaa
    50581 tacccatacc agtctcttcc actgccattt ttgctagagg tattctttgt tgattagctg
    50641 cagttgaagc agctaagaaa atcttatcta cctgttcttg cgtaaatgtt gcaaattctt
    50701 tttgtgccaa tctaatttct tctaatctca ttcttaatgt ttcaacactg ttgacaattt
    50761 caggactaca tacttcaaca tttgattttt ctactacctt ttcttttttc tccatactaa
    50821 aaacctccct aaaataatta tgcatctcta atttttataa atcttaaatg catcatctat
    50881 atttttaact tatacttaaa ataattttat agatttcatc tctatacctt agattttatt
    50941 tattttactc tcttaggtca agaagttttt ttctgaatat tttgtcaatt tattttttaa
    51001 caaatatatt atttttttta cttttactaa aattttttat ctaaatgaga tatatttcat
    51061 ttgaataatt tacttcgact aaataaaata ctaaaatgat aatttatatc tttcattttt
    51121 tttacttatt aaattttata tgttatttgc atgttatttg tataagtagt aaataaaatt
    51181 tttgtcgtat ttttataaaa taacacttat ttttgacttg tatgcaattt ttctttttat
    51241 aacaactgta tagttttaaa aaatatataa actaaaatta ttctaatctc tataagttat
    51301 ttttaagtca atatgtaata attatgcttt tcatatagat aaataatttt tatattaaga
    51361 ccgttaattt tttaatgata a
//
LOCUS       DAEPXW010000016        50619 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.016, whole genome shotgun sequence.
ACCESSION   DAEPXW010000016 DAEPXW010000000
VERSION     DAEPXW010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50619
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.016"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(187..2157)
                     /gene="ftsH"
                     /locus_tag="KRM55_000937"
     CDS             complement(187..2157)
                     /gene="ftsH"
                     /locus_tag="KRM55_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH1593194.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(2191..3579)
                     /gene="tilS"
                     /locus_tag="KRM55_000938"
     CDS             complement(2191..3579)
                     /gene="tilS"
                     /locus_tag="KRM55_000938"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBH1593195.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(3762..4190)
                     /locus_tag="KRM55_000939"
     CDS             complement(3762..4190)
                     /locus_tag="KRM55_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBH1593196.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEENIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(4207..5013)
                     /locus_tag="KRM55_000940"
     CDS             complement(4207..5013)
                     /locus_tag="KRM55_000940"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBH1593197.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDNIQKVEIQKY"
     gene            complement(5215..5700)
                     /locus_tag="KRM55_000941"
     CDS             complement(5215..5700)
                     /locus_tag="KRM55_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBH1593198.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(5751..6410)
                     /gene="spoIIR"
                     /locus_tag="KRM55_000942"
     CDS             complement(5751..6410)
                     /gene="spoIIR"
                     /locus_tag="KRM55_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBH1593199.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(6555..7235)
                     /locus_tag="KRM55_000943"
     CDS             complement(6555..7235)
                     /locus_tag="KRM55_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1593200.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(7219..8109)
                     /locus_tag="KRM55_000944"
     CDS             complement(7219..8109)
                     /locus_tag="KRM55_000944"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBH1593201.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(8227..9777)
                     /locus_tag="KRM55_000945"
     CDS             complement(8227..9777)
                     /locus_tag="KRM55_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBH1593202.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(9871..10137)
                     /locus_tag="KRM55_000946"
     CDS             complement(9871..10137)
                     /locus_tag="KRM55_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBH1593203.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(10285..11145)
                     /gene="yabG"
                     /locus_tag="KRM55_000947"
     CDS             complement(10285..11145)
                     /gene="yabG"
                     /locus_tag="KRM55_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBH1593204.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(11229..12167)
                     /locus_tag="KRM55_000948"
     CDS             complement(11229..12167)
                     /locus_tag="KRM55_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBH1593205.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(12277..12438)
                     /locus_tag="KRM55_000949"
     CDS             complement(12277..12438)
                     /locus_tag="KRM55_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593206.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(12448..12945)
                     /locus_tag="KRM55_000950"
     CDS             complement(12448..12945)
                     /locus_tag="KRM55_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH1593207.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPSDQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(13060..13770)
                     /locus_tag="KRM55_000951"
     CDS             complement(13060..13770)
                     /locus_tag="KRM55_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBH1593208.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(13946..14476)
                     /locus_tag="KRM55_000952"
     CDS             complement(13946..14476)
                     /locus_tag="KRM55_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593209.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(14493..14723)
                     /locus_tag="KRM55_000953"
     CDS             complement(14493..14723)
                     /locus_tag="KRM55_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593210.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(14738..16132)
                     /locus_tag="KRM55_000954"
     CDS             complement(14738..16132)
                     /locus_tag="KRM55_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH1593211.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(16258..17511)
                     /locus_tag="KRM55_000955"
     CDS             complement(16258..17511)
                     /locus_tag="KRM55_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1593212.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(17562..18716)
                     /locus_tag="KRM55_000956"
     CDS             complement(17562..18716)
                     /locus_tag="KRM55_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1593213.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIKKLK"
     gene            complement(19276..19845)
                     /locus_tag="KRM55_000957"
     CDS             complement(19276..19845)
                     /locus_tag="KRM55_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1593214.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            20048..20275
                     /locus_tag="KRM55_000958"
     CDS             20048..20275
                     /locus_tag="KRM55_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1593215.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(20494..21237)
                     /locus_tag="KRM55_000959"
     CDS             complement(20494..21237)
                     /locus_tag="KRM55_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH1593216.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            21405..22277
                     /locus_tag="KRM55_000960"
     CDS             21405..22277
                     /locus_tag="KRM55_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1593217.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            22277..22942
                     /locus_tag="KRM55_000961"
     CDS             22277..22942
                     /locus_tag="KRM55_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH1593218.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            22963..23820
                     /locus_tag="KRM55_000962"
     CDS             22963..23820
                     /locus_tag="KRM55_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1593219.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(23976..26522)
                     /locus_tag="KRM55_000963"
     CDS             complement(23976..26522)
                     /locus_tag="KRM55_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1593220.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLKLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVTKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(26522..27208)
                     /locus_tag="KRM55_000964"
     CDS             complement(26522..27208)
                     /locus_tag="KRM55_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593221.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(27291..28280)
                     /locus_tag="KRM55_000965"
     CDS             complement(27291..28280)
                     /locus_tag="KRM55_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1593222.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(28267..28953)
                     /locus_tag="KRM55_000966"
     CDS             complement(28267..28953)
                     /locus_tag="KRM55_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593223.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(29453..32659)
                     /gene="carB"
                     /locus_tag="KRM55_000967"
     CDS             complement(29453..32659)
                     /gene="carB"
                     /locus_tag="KRM55_000967"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH1593224.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(32852..33901)
                     /gene="carA"
                     /locus_tag="KRM55_000968"
     CDS             complement(32852..33901)
                     /gene="carA"
                     /locus_tag="KRM55_000968"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH1593225.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(34158..37364)
                     /gene="carB"
                     /locus_tag="KRM55_000969"
     CDS             complement(34158..37364)
                     /gene="carB"
                     /locus_tag="KRM55_000969"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH1593226.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(37417..38460)
                     /gene="carA"
                     /locus_tag="KRM55_000970"
     CDS             complement(37417..38460)
                     /gene="carA"
                     /locus_tag="KRM55_000970"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH1593227.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(38486..39202)
                     /gene="pyrF"
                     /locus_tag="KRM55_000971"
     CDS             complement(38486..39202)
                     /gene="pyrF"
                     /locus_tag="KRM55_000971"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBH1593228.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(39578..40213)
                     /locus_tag="KRM55_000972"
     CDS             complement(39578..40213)
                     /locus_tag="KRM55_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBH1593229.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(40237..41151)
                     /locus_tag="KRM55_000973"
     CDS             complement(40237..41151)
                     /locus_tag="KRM55_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593230.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            41752..42981
                     /locus_tag="KRM55_000974"
     CDS             41752..42981
                     /locus_tag="KRM55_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1593231.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(43186..45567)
                     /locus_tag="KRM55_000975"
     CDS             complement(43186..45567)
                     /locus_tag="KRM55_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBH1593232.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(45539..46264)
                     /locus_tag="KRM55_000976"
     CDS             complement(45539..46264)
                     /locus_tag="KRM55_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBH1593233.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(46254..46709)
                     /locus_tag="KRM55_000977"
     CDS             complement(46254..46709)
                     /locus_tag="KRM55_000977"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBH1593234.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(46991..48172)
                     /locus_tag="KRM55_000978"
     CDS             complement(46991..48172)
                     /locus_tag="KRM55_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1593235.1"
                     /translation="MKNKSLLNHMFRPILDIIISCALTSMLILTSMYIIKSLYFNSGI
                     SVINQLVYQLRDLRSLIGESLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(48162..48854)
                     /locus_tag="KRM55_000979"
     CDS             complement(48162..48854)
                     /locus_tag="KRM55_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593236.1"
                     /translation="MNNTILVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(48988..49704)
                     /locus_tag="KRM55_000980"
     CDS             complement(48988..49704)
                     /locus_tag="KRM55_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1593237.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDNDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            49829..50563
                     /locus_tag="KRM55_000981"
     CDS             49829..50563
                     /locus_tag="KRM55_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH1593238.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
BASE COUNT        15974 a         9252 c         5684 g        19709 t
ORIGIN      
        1 ttttatattg atgatttata taattttaca ttttatttaa ataattttaa aataataaaa
       61 aaactgaaag tatcaattaa attaatacat gcaaatataa tttgcttatt aatttaatat
      121 tatactttca gttttagtat ttaatccaca tcagataata atcttaaaat gaccaaggtc
      181 ttaaaactat ttatctttat cagatttatc ttctaaattt ttatttatat caataacatt
      241 gtttctttct tcttcatctt tttctaattt tatagttaat tgttcttcaa cttctttaga
      301 agaattttcc tctgtaactg cattttcaat ttcattcaga ggtaactctt tattaaatgc
      361 ttttacaaat tgttctgcat ctaaagtttc atatataagt aaagcttgtg ctacatactc
      421 taatctatcc atattttctt gtaatatact tcttgtctta tcatatgcac catcaactat
      481 acgctttgtt tcttggtcta tctcaaaagc aacttcttca gaataatttc tcttacttga
      541 aaaactatta cctaggaata cttcatcatc actgtcaaat gacattggac caagtttaga
      601 actcattcca tactttgtta ccatacttct tgcagtagct gtaactcttt ctaagtcatt
      661 tgaagcacct gtagatacat ccttaagtac tagctcttct gctactctac caccaagtaa
      721 aactacaata ttttctttca tttcattttt tgtagcatag aacttatctt caacaggaag
      781 ttgcattgta aaccctccag ctcttcctct tggaactatt gtaacttgat gaacaggact
      841 tacttcttca agtacatggg cacaaactgc atgccctcct tcatggtatg ctgtaagtct
      901 tctttctttc tcacttatta ctttcgattt tttagccaca cctgctataa cctttgttat
      961 agcttcttct atagtttcca tcttaatttt cttttctctt tttctagctg ttaatattgc
     1021 agcctcattc attaagttct ctatatcagc aggagtaaat cctggtgttc ttctagccaa
     1081 gacatccatt tttacatcat cacttaatgg tttatttctt gagtgaactt taaatatagc
     1141 ctctctacct tttacatctg gtgtaccaac aacaacttgt ctgtcaaatc ttcctggtct
     1201 aagtaaagct gggtcaagta tatctggtct atttgtagct gccatgatta ttataccttg
     1261 atttacccca aatccatcca tttcaactag aagttgatta agagtttgct ctctttcatc
     1321 atgacctcca ccaagacctg cacctctttt tctaccaact gcatcaattt catctatgaa
     1381 tatgatagct ggagcacttt tcttagcctg ttcaaataaa tctcttactc ttgaagcacc
     1441 aaccccaaca aacatctcaa cgaaatcaga accacttata ctgaaaaagg gaactcctgc
     1501 ttctcctgca actgctcttg atagatatgt tttaccagtt ccaggaggtc ctaccataag
     1561 cattcctttt ggtattcttg cacccaattc aatatatttc ttaggattct ttaagaaatc
     1621 tactacctcc tgcaaatctt ctttttcctc atctagtcca gctacatctt taaatgtaac
     1681 tctagttttt tcatcatctt tatgaacctt agcttttgat ttgccaaaac tcataacctt
     1741 tccgcctcca ccttgagact gattcataaa cacgaaccaa ataatcacca tgaagaatat
     1801 taacagtaat gtaggcaaca tttcgacaaa ccaaggtgta gatggcttag cttcaccacc
     1861 aaaagttagt ttcccagcct tagcttggtc taacacctca tctgcaagtt tatttcccat
     1921 cacttctgtt ggaacatatg acttaaactt tgtatttgta tcttttatag taccttctac
     1981 agaagtttga tttacaaagt ataatcttga tatattctca tctgttaatt ctctatatac
     2041 ttcagagaat tttaaatctt ttattttttc tgtaggctta cctgagaatt gaactatacc
     2101 tactataatt ataaaaacaa gtagataaaa acctgcccct tttagcaact tattcaatat
     2161 agaagccctc ctttcataca ttgctttgcc ctataatttg ttaaaattaa tttttaatac
     2221 ttcttttgtg ttttcatcaa ttttataatt ttcactgatt ttataatctc caacacatat
     2281 tattccttca ctatctgtga ttataggaat tttacatctt tcttctcttg ggatttttaa
     2341 atctatgaat aaatctttca cttttttact tcccatagca agctttatct tatcaccttg
     2401 ccttctgctt cttattacta tacccccttt taccttatta aaatcaaacc ctttagatga
     2461 attgtctaat ttcatactct tatacctatc tatgctcatt acttgggtct caataatttg
     2521 ttttaattct tttattttaa taaacccatt actaggtaca ttgtaataaa attcaatttc
     2581 ctcattaaca atttcctcat tcgttaatat tatactgtct ttttttctat aaacaaatat
     2641 atttcttgga agagttaaca ttttatttac ttttgaatta tcttctaaag acattatatc
     2701 ctctatatgt ctttggtcaa caaaattagt atctcctagt atatgtttta tggaatttct
     2761 aagaactcta actttgatag catcatgtaa gcaaacaaaa tcgtctaaat ttatctctac
     2821 aaagcctttt tcttttatat tcgaaacttc tctaaattta gcttctgcct ctttctcaat
     2881 ataatcgtta tcacttttta aactattgct catcctcact atagattcta ttacatttga
     2941 attaaaatta tccttcatat atggtaaaag gtctaacctt atcttatttc tagtgtatat
     3001 attttctaaa tttgttttat ctatcctcgg atttaaatta taagcttcac aatactcctc
     3061 tatctcattt ctttccacgt ctaatatggg tctaattatg caattatctc taatataatc
     3121 aattcccttt aaacctttta aacctgttcc tctcatgata cgcatcataa cagtttcggc
     3181 ttggtcattg agattatgac ctattgctat tttattggct ttaatcttat ccttaatttc
     3241 ataaaacatt tcatatctta gcttccttgc tccttcttct aatgataatc cctcattttc
     3301 acaatatttt ggtacattaa tagactttac aaagaatata attcccatat cctcacaaag
     3361 tttagataca tataatgcat ctttttgagc ttctatccct cttatttgat ggtttaaatg
     3421 tgctgcatat atttctatat taaaatcttt ttttaatcta tttagtacat gcaataaaca
     3481 aactgaatca ggtcctccag aaagacctaa aactatttta tcgccttttt gtattaaatt
     3541 atgtttattt atagtactta gtaccttatc aaatatcata tttatccctc ttacacttag
     3601 ttttattcac ttttaagtat actttctata aaaaaacgct aaacccttgt atcaatttta
     3661 agaaattaaa gtttaatata aatataataa taccaaataa attaaataaa aggtagtttt
     3721 ttcactacct ttataaaatt tctggaaaat agccatagtt attatttagt acctatgtat
     3781 atatctattt tattcctacc taaaaataaa tcttgtacct ttatattata gtctattttc
     3841 aattttatgt gttccccttc ttgtatattt atatctaatt ctcttgtatc aatatcaatt
     3901 aataaagtac cttgtggggt cacatacttt gtagtactac tttctccaca tttaaacagc
     3961 attgttgagt taatagcacc aaactttttg atactaactt gatttttaag tatctttata
     4021 gtattagtta tttctatatt ttcttctttt tccttgtaaa taacatatat tccatcattt
     4081 ttataaaaaa ttttaccaaa ggcagtcatc tctatggtgt ccatatttcc tttttcatca
     4141 tattgtctag tatttatact tatttttaca ctcaacgatt tttcctccat agattcttca
     4201 tataaactag tatttttgta tttctacttt ttgaatatta tcaatttttt tctttaagaa
     4261 ctctcttgct atatctgaaa atttttcagg tatatctgat acataatatt gataagttcc
     4321 atgaatttct gtattgttta taatattttg cacctctaaa atctttttta aatcctttgc
     4381 agtctcttta gctggattaa caagttttat atgctctcca acttcttcac ctattgttct
     4441 ctttaaaata ggataatgag tacatcctag cactaaagaa tctatatttt tttctttcaa
     4501 ttcttgtaaa tatatctttg ctgtcaattt agccacttct gtatttgccc atccttcttc
     4561 aacaataggt acaaataaag gacatgcttt attaacaatt tctatactct catctatttt
     4621 agatatttcc aagttgtatg cttttgaact tatagttcct tcagttccta ttattcctac
     4681 aattttgttt tttgtagaac ttacagctgt tctagctcct gcttctataa ctccaattat
     4741 cggtatatca tatttttctt gagcttcttt taagcttctt gcagtagcag tgttacatgc
     4801 tataactata gcttttacac cttttgtttt taaaaagttt atagcttgaa aagtatattt
     4861 aattatagtt tctttggatc ttgaaccata tggtattctg gcagtatctc caaagtatat
     4921 tatatcctca tttggtaata tcttcattat ctcttttaga actgttaatc cacctaatcc
     4981 cgaatcaaaa actcctattg gtttattgtt catctttata caacacctac tttacatttt
     5041 tgtgtttaac aacaacttat ttatcgctaa aatttatatt tatattcata attaatatat
     5101 tattacctaa atgattatta tagtttattt tacacaaaaa ataaaggagc tatcttaaat
     5161 tagaaaataa tttctacaaa aagacaactc ctttcactac ttaaaaattt aaatttattt
     5221 tgcaaacaca tgatttccta ttctcatata aggattcaat ctatttatcc atttgcaagt
     5281 ggctatttct ggattccaaa aatatactgc tttattagtt gggtcagttc cataaagagc
     5341 ttcctgagct gctttacgtg ctgagtctgt tggtgccatc tttattgaac catcaagcac
     5401 aactgagaaa gcattttttt gatatatgac ttcttctatt gtgtctggaa atctagggtc
     5461 caatactcta tttattacta cagctgctac agcaacctgt ccctcatagc tttctcctct
     5521 agcttctcct gcaaccaact tagataataa catcaaatca ttatcagata aatttattac
     5581 ttctttcttt gctatatttt tttcttgttt gtttactttc ttaatatttt ctgttggttc
     5641 atatgcaaat acctctttaa taggcataaa tataaaagtc aaagctaata gtgtagccat
     5701 cagtttactc cacctgtcca tgattaaaac cactccttac attcttattt ttaaaatttt
     5761 ttctctaaat ccttgactac ttcaagtact ttaaacttaa tttttactct acttgttttt
     5821 tttggtgtat cttgttttat taacttatat tctttatcag ttaaaacttc cttcaactta
     5881 tcatctgtag atttatctat cactccatta gattcatcaa caaaacatag tggagggaac
     5941 ataacacacc accagttttt tccttcacct ttcccaataa taatctttaa tgctttatat
     6001 tcaccagctg gaagaactat attagaatat tgtttagtag ggaaattgct atattgtata
     6061 cctaccttta cactgtaatt atatccattt ttaagaataa tatttttact tatttcttcc
     6121 agactactat attccttttt tataatagct tcactttctt ttatactttt tgaattttga
     6181 agctttggct gtaaatattt tattacttca tctctaactt ttagtttaag ttcttggtct
     6241 tcatctgtat tgctgtttgc tataacatga aatcttatta atttatcttt ataatctttt
     6301 gatatattgt ctactttttt tacctcacca tttattacta ttgtcattat tgatatgact
     6361 gatataagac ttaatattaa tagtcctaat ctaatcttaa tttttctcat tgaaaattcc
     6421 ccctcaagat aaatttatat catcaattat gtccaattaa atttaattta ttcataatat
     6481 tttttaatac taataaaaaa agctatctta aaatgattac aatcatttta aaatagcttt
     6541 ttaaacctta tattttataa gtctttacta atcatagcct tatctatcat aaactgctct
     6601 gctttttcta tatgctctgt agcatacttc ttggatagct cactatcacc tttaattata
     6661 gcatcaagta agtatttatg ctcttcaaca atattatgtg atgtatcata agcagacata
     6721 taggtaactc taaatctata tacttgttcc cacaatgagt ttattaattg gattaatttt
     6781 ttattattag ttgctttaaa tatacattca tgaaattcta catcaagttt taataacgca
     6841 tctacatcgg attccaaagt gcttttttta aattcttctg atatatcttt aagcttttta
     6901 atatcttcat cactaattct ttcagcggca agatatgctg ctaagccttc taggcttgct
     6961 cttacttcta atacatccat aatatccttt aatgacatat ttgccacata cgcacctttt
     7021 ctaggcaaca taacgactaa accttctaat tcaagctttc ttattgcctc tctcactgga
     7081 gtcctactta ctcctaattg ttctgctagt tgcacttcca ttagcctttg accaggcttt
     7141 aattttcctt ctaagattgc ttctcttaaa ttctcaaaga ctacatctct taatggcttg
     7201 taattatcca agttcagttt agttaaattc tccacaaatt tcaacccctt tttgactgct
     7261 attaacaaca tacacctgtt tatatttttt taataattct ttttttccaa ttagagcatc
     7321 ttctttattt ttaaatagcc caaaaactgt aggaccactt ccactcatca tagaacctaa
     7381 agcattattt ttcatcatta cttgttttat atcacttatt tctttgtgtt tacctatagt
     7441 aacattttca agaatattta ccatgctttc tgatacagct tttatatctt cagattttaa
     7501 acactctatc aaatatttat tatttggtct ttttttaata ttattcaaat ctaatccttg
     7561 ataaacttct ttagtagaaa cgaataagtc tggtttgcat atcaatatat ttgtatcaca
     7621 tggtaaacct ttgatgtttg ttagcttttc tccaatacct tgagctaagg caggtcttcc
     7681 tgatatacaa aaaggaacat ctgcgcccaa attaagtcct atttctttta attcatcttc
     7741 agataatcta agttcccata ggtgatttaa acctactaat actgcggctg cattagaact
     7801 tcctccagcc atccctgctg ctacaggaat atttttttct atgaatattt ctacaccttt
     7861 ttttatataa aatttatttt taagtatttt ggcagcttta taaacaatat tatcttcatc
     7921 taaaggaata tctaaactag tgctttttac ctttatttca tcttcgtcta attcttttat
     7981 ctttactata tcgtataaat ctatcgtttg cattatcatt tcaacaaaat gataaccgtc
     8041 ttgccttttt cccaagacat caatggataa atttattttt gctctactct ttagtcttat
     8101 aaaatccatt ctatcctcct tgtttaaaga ataatgcatc actaacaata atattatact
     8161 acaaaaaata aaataatagg gtattataat accctattat acttaattac tttaaatttt
     8221 ttaatattaa tctactaata cgactttttt ttctaaaata agacacttac caggcttaat
     8281 tggttcatca agttttatat cattaagttc tgcaatttca ttttctgttg tattgtattt
     8341 ttttgctata ttccagaaag tatctccttc tttgcatata tatacgatta tgctaggagc
     8401 tttagataaa tcatatacac cttggtcttc tcccttgata ataaaatttt ctgctttctt
     8461 atctaatgct tcagtaaatc tcttaatttt gataatcaag tctatctggt ccctattcaa
     8521 gtcaacttcg actttatcaa tacatgctgt attaaacaca gatgctgtat cagttagatt
     8581 atccatttct atatcatgtt caaatggaat ttcctcacta attttataaa ccaattttaa
     8641 accttcaact gggacaaata aaatttcaac ttttatgatt ccttgtataa tgcttttatt
     8701 tccttcaata taactatttt ctatagacat ggttggacaa acgcttacaa tatcttttat
     8761 ttgtatatca tcattatcat ttcttatgcc ttctctaacc ataaatgttt cttcactacg
     8821 tcttaaagtc ttatttaatt gaataggttt gtggtcaaat tttattatct tttgaggcga
     8881 atatgcatct tgtaatactt ctcttgtaac ttcatctgta acttttacct tacaacaagc
     8941 catacaatct atttctaaaa gacctgtgtt gctttcacta ttttgcttga aaatatgatt
     9001 aaaatctgac atagacaaca atacttcttc agtcatacca tcactaactc cagggacttc
     9061 tacaaattga gtaaactcaa tacctactct atccaactct acaagttcac cctcatatgt
     9121 acaagctaac ggatttattt ctaatactcc accaataata actttattgt cagtcactct
     9181 actttctttt actttaacac atggatttaa acttattata gattgaattt cctctgtgtt
     9241 tattgttata gtatctctta tagaactttc tgctttttct attccaacta tatcttgaaa
     9301 acaaatttcc tttctgtgct tttgtatgcc ttccacttgc gccacatctt ttacaatgtc
     9361 taacctttgc ttttcaaaca aacttcccct tatattcata agagctccta ctttaatctt
     9421 tctctcattc attatagtac aatccatatg ctctacttct gaaaataaca tgtattccat
     9481 atcttgaata acattgtctt tttctattac ttcgtttata tctacttttc cgtctacatt
     9541 agaaatagta tttttatcat ctgcaatata gattacatta taattaaaac tacctctgca
     9601 aagtatcttc ccatctgcca tttcaatttt tttaagtgat atgtatcctt ctgtttttac
     9661 aatttcatat acatctaatt ttttgtctgg tacaactgcc tccgcttcaa tgaatgtttg
     9721 aaattttcca aagtctattc tattgtcaac tttaattaca tctttaatta attccatagt
     9781 ctacctcctt aagtattata aaaatatcac actatattta tatttaagga gcaaaaaaaa
     9841 aattacacct atttttaaat aggtataatt ttaacttatt tgtaatttat cttgatctct
     9901 aaaaacttgc aactttacat tagatgttaa taaatctgag taactataag atactctagg
     9961 atatccatta ctttcatcat ctaactttat aacaaacacg cttggataaa ctttttctag
    10021 tataccctct tttgtaataa tctgctttct tcctttatta gctttcaaca atattttctt
    10081 tcctatatgt ctctctaagc ttactcttat cttatctaga gtttgaacag tagccacaat
    10141 atcaccttct ttaacgttta tatgtttaca taatatcaca tataaacatt tttgtcaaat
    10201 gtttaaacta attattttat atattttttg caaaaatgtc aatactattt ttgaagatat
    10261 acagtataat tatgttaatt tttgctaatg taatattgtt tttggcattg cccatctaaa
    10321 ttttcctctt gtttcagaac caccaattcc cttaacacct gtaatagtct gctctataac
    10381 ctcatcaata ggaactacta catcaattct tgaacaagca attttctcca ctataaaaac
    10441 agggtctaat gcatgtatca ttattcttcc aggtgaactt gcatagtttg ctcctgcact
    10501 tattattttt tcataatttg attggcatgc tcctgcgaat atgacaagat tatccaaatt
    10561 tggttgccat ttacgtgctt cttttactgt tttaacaaaa tttgaagagt ttctatagtt
    10621 actcatatct tctatatctc ctctttttat tgtcattgca tcatgacctg ttattactag
    10681 tatatccgga ttatattttt ctagtagtgc tcttacttct ttatactgat tttgctctga
    10741 aacagctaca cctactgcag gtattccaag ttgagcatat acatccaagc aaatttttaa
    10801 atattcttta tctccatcta tctgtagtac ttttccaggc attccatatg tgttaggatt
    10861 taattgaagt tttggaactg ctctagtcat tcttttttgt ctttctttag cttttcttac
    10921 tgacttatat aataaatttt ctacattttt atctattaat atatctttta tatcaggtgc
    10981 ttttactaat tctaggtcat caatataagc atctgctatt actctaaatg caattccctt
    11041 tagtatagct attttctcat tattttcatc tacaccaaaa gagactattt taaatactat
    11101 atctttgtta tgtgactttc tagctacaat gtctcctacc ttcatagtta aacctccaat
    11161 aaatttttat cttagtttat actatgttcg atataaaact ttgtttccta atgtcaaaaa
    11221 aacatttctt ataatacttc ttttatcact cttaaagcat ttttatagta tatcttttct
    11281 atatcatctt cactaaaccc ttcttttttt agaggttcat acagtttacc catctgagat
    11341 atatcttcaa tctcaacttt tgaatctatt ccatcaaaat ctgaccctag ggatacaaca
    11401 tctatccctc caacatttac aatatgtttt atgtgtctaa ccatatcttc aagtttactt
    11461 tcacttttat cacttaaaaa taagtggaag aagtttatac ctgtaactcc acctttattt
    11521 gctaatactt taatcatatc atcagttaaa tttctagaat gattcatcat tgctcttgaa
    11581 ttagaatgtg tagcaattat tggtttagaa gaaatctttg caatttcata aaatccacca
    11641 tctgaaatat gagaaacatc aaccaacatt cccaattcat tcatcttatg taccacttct
    11701 cttccaaaat cagtaagccc tttttctcta tattctactt tattatgagg aaagctcaat
    11761 tcattcacat gattccaact tattgtcatc attctaaccc ctaagtcgta aaatttcttt
    11821 aaattttcta atttaccttc aagtactgca ccttcctcaa tagataaaag agctgtaagt
    11881 ttaccttctg attggttttt cataatttct tcatagttag tagctaaagc tatttcatca
    11941 ctattttttt tcatttcctc atgaaattta tttgccatac tcatgcaata atcaaaagga
    12001 tgttttactt cttcagtatc aacaaaaaga gcaaatgttt gagctaatga atcccccttt
    12061 ttcaatctgt ctatatcaac agaatattta ttagacttaa gttcacttgt ttctacattt
    12121 tccattaatt ttgctatagt atcacaatgt aaatcaataa atttcatatt tataccccct
    12181 gtatatttta tatttatatc taaaaataga aatagttgtc cttatagaca actattgaca
    12241 actatttttt aatattcttt ttaatattac ttaatcttat tcttctttta agttaggtat
    12301 tactttttta acttcttcaa tttgatgcca tgttttatct atattatttt cactaatata
    12361 tttttttaaa tcagttaaag atgtaaaatc tttaactgat aaattgtcat catcatctgc
    12421 aaatcttaaa ataaacatga gactccctta ctttccacaa catttcttat atttttttcc
    12481 gcttccacat gggcatgaat catttcttcc tatttttgct tctttaacta ttgttttaga
    12541 cttcttataa gcctttatta tttcttttct ttggtctgat ggtagtatat cttcccaacc
    12601 ttgtaaatta tatagccaat gagcctcaac agttaccata ttgttatata atttttccca
    12661 atctattttt atagaaactt ctttatcagc ttctacttct tctaaaacta tatcttcttt
    12721 taagctttca cttattccat ctatgaatcc catgaaaaat tcattagtag ttccaaattt
    12781 ttcagccaat tcacttactt taccttcaac aacatccatt ttattattta atatttcatt
    12841 gtatattcca gcttcaactt tcaaatattc ttcccagaat tttacttctg cttcttgact
    12901 ttcatgatta tcacttaaat ttctccattc agtatataaa ctcatacttt ttcctcctaa
    12961 gtatacctat atttttatag tttttatagt ataaaatctt ttagttagat tggaagtttc
    13021 ttctttttga ttataccata ttctatttaa agttaactct tatattatat cataattaaa
    13081 caattctttt aatactttta tagcatactc ttggtttata aaataagggc ttgtcgcaat
    13141 tgttattact ttggcttttt taattaagtt ttttatcttg taaaatttga gttcaaatgg
    13201 tatatagtcc atatcacttg aaaatatatc caaatctatg tcaagaacaa actctgattc
    13261 tacttctaaa tcaaatccat atagactatc tattattatt aattctgaaa atatgttata
    13321 ttttaaagca ggttttataa aacttcccac atttaaaact tcatttgtat atctaaatac
    13381 atcttttaga ttatttacat ctacatcata gttctcaggt tctctagtat ccttatgttg
    13441 gtctacatgc actaacttgc atccttttgt aaactcaccc tttaacaaag attttgccca
    13501 aaaataaaat gcatggttat gattgtcaaa cacatatatc tttttatttc ccaggacata
    13561 ttcgaccata ttctccaatc cttttgcttt tatttcctta ttttcatcta cttcattaaa
    13621 tactacctca ttgcctaacc ttacatcatt taatgtacca tttattagtt ttggaacgta
    13681 tatgctctta ttttctcttt tatcatatga aaatacatta tttcctactg gtttttctat
    13741 ataaaatcca ctatattcat aattttccat aaaactttat ttcctccatt gttatataaa
    13801 tatataagtt ataattttaa aaattaaaat gcacttattg taaatcatat catctattat
    13861 agaaaacatc ttatataact aaatataata tcttctctca atatgtatta tacaataagt
    13921 gcaaaatata tttatataaa atatactaca ttcctataac aaaaccatca gcttcaattg
    13981 gaaggtaact aactcttcta ttcaactcca cctttccaaa aaatactacc caatatggtc
    14041 taaaaatact ttcaatttta actatttcaa tctctgggat tcctcccata aacctatgag
    14101 ttaatctcat agccatttta tttgcctttg cttttactct tcgttcgtcc ttatcactat
    14161 actgcacaat attacaatcc acatttttta caacttcata tgtaggaaaa tcttgtacta
    14221 tactaccaga acctgtagaa ccattcacta aaatttttaa ttcatttata tcattagaat
    14281 atctcctatt cttgaaaatg gatttcgttt tgtgaatttt aagtgtgata attttaaact
    14341 ctatataatg aagtctaact tcatgagcat atttgttctt taatattagc ttactaaata
    14401 aagaattttt tccactttta gctatctcta tagcttcttc ttttgtaatt cttataggta
    14461 acgctcttat atccataaaa tcattctctt tcttattttt ttcttgtcat ttttaaaact
    14521 ctatatatat aatcaaaaaa tattacaatt acaactgcca taactccata tggaattatt
    14581 tttccaacta taatatcatt tctagtcaat ataccataaa atataaatcc tgttattaaa
    14641 aagtacaata atactagaaa accgtctatt ccaagccatt ttatttctaa atcttttttt
    14701 accttagaca ctaatttaga catagcagtt tctcctttta tagattattt tgtgtattta
    14761 aattttcacc tattctatta ccaatcatcc atgcaataaa tgaaaaaggt atagctatca
    14821 caagaggctc taactcaaag ctctgaactg gaaatatttt aaaataacca aaagtcactc
    14881 caccaacaat cattcctaaa ataccaccca tagatgttct tcttccattt ccaagaagcc
    14941 cacctactat aggtacaaat gccgaaccca tccaaatact tcctacaaat atacatgcat
    15001 catatacatt ttcaaatcta aatgctacgc taagccccat aactgctgct aaacatacac
    15061 ctattctagt aaactttact aattgtttct gagataactc tttttttgta attcttccat
    15121 atatatcatt tgctaatgta gccccagctg ctagataata gctatccaat gttgatatta
    15181 tagaacctaa aattcctatt ataaatatta ctcttattcc ttgtggtaat gtatctaaaa
    15241 ctaaagttat atatccagca gctggagcca tttctggata agtagctctt actataagtc
    15301 ctgtcatagt taacaccatg tcaaaacata tccatagtga aaaacaggtt aataaggctc
    15361 ttcttccaac cttaggagaa tctgctgctg aaaatctttg ataaaaagtt gggtctgaat
    15421 aagctccaaa agaatataca attaacatca atgctttcat agctgacata ccttttgtag
    15481 ggtgcataag ctgtggtgca tctttgagtg cttctgtaag accttgaaac cctcctattt
    15541 gttcaaattg acctggcata accatagtta aaccaaatac catacaaaaa aacaatacca
    15601 tatctgtaat ggcaactccc ataagcccac caagtactgt aagtacaacg actactccta
    15661 ccattattaa tcctattaat tctttatcta ttttccatgc tacgttacct atagttccca
    15721 tagcagttat ttctccaagt tgtgcacaat atataaacat caaaattgcc ccaattatag
    15781 caacatgctt gccataaaaa ctttccagta aatcaggaac tgttatattg gttcttatat
    15841 gaatccttgg accaacccac aatgctaaag gcattctccc aatatgtgca gctattgacc
    15901 aaactgccca tgcagatatt ccatatatag ccgcatactc tacactacct actgtaccaa
    15961 ctcctccata ccatgatgca accaaagttc ctactattaa ggaccatggt aaacttcgat
    16021 ttcctaggta ataactttcc atatctttta catttctaga aaaataataa cctattccta
    16081 ataatataaa tgcaaatata actataatcc cattttccca aaatgttaac atatctaatc
    16141 tccacattct tatattttaa tttttaactt taatatctaa atatgaacaa ctctacccat
    16201 ttccataaaa ataggtagag ttatataata attataagta tttaagtaat cttgttatta
    16261 agcaatttta ttgtttaaac ctttattttc tcttttattt attttattta aagcataagt
    16321 agcaaatatc cctataactg cacatactac agataaaata aatatatatg tatatcctgt
    16381 ttgtccatat ttatctaacc aattacctgc aatagtgtaa taaaacgcat ctggagaaaa
    16441 tcctataaat gaagcaaatc caactactgc tcctgtagtt tctaaagata tattagactc
    16501 tgaaacagat gcaaagtata tacctctaaa tccaaataaa attacactta gtattatcat
    16561 gtttattaca gctatccata taaatcctgt actcttagga ataaccaagt aagcagctgt
    16621 acttactgtc attaatataa atcctacaaa cattactctt atagatgaac caactttatc
    16681 tgttataaca ccagcaactg gagatgctcc catttttata acataagttc ttattattga
    16741 taaagcagaa actagagtca ttggcattac ataaacttct gataagtatg gacttaaata
    16801 agttaaactt gagaatacta aataagttga aaatattata agaccaatta accaagcctt
    16861 tggcattgta actactttta acaatgactt aatacttaat ccttcatctg atgctccact
    16921 atcttttttc tcttctacta agaaaaatag aagtatacca catattatag atgctgcaga
    16981 atataaccat actacatatt tgaatcctac tgttatttca gcaaatttac caaagaaata
    17041 aagacctata aaagaaatta atgtacctga tacacctgat aacccttcat aaaaaccaaa
    17101 tattcttcct tgctctgact cacttccttg cattctaaca accttaacag aggctgagaa
    17161 gaaggttaat attgtcgtaa atccccataa tacaaatatt aaaagtatca tactatatga
    17221 tgggaatgta gagaaataaa atccaagtat tcctgaagca attaaagaaa aagttattaa
    17281 ttttctaact gagaatctat ctgcaaacca tcctcctata aaataagata ccattcctac
    17341 taatccatat aaactcaata agttccctat ttgtgtatga cttaatgcta aagcttgttg
    17401 cattgggtca taaaatgatg atttcatata tggtaaacta tacatagctg ttgttccaaa
    17461 tgccaatatg aatattatca aaaatctttt aacattattt ttgctttcca ttgattctct
    17521 ctccttaaaa ttttattgtt tataatctca ttcatgtaat tttattttaa tttttttatt
    17581 gcttgtttaa agtcatttat tatatcattt gaagattcta atcctacagc tattcttatt
    17641 agattttccc cattcatttg aactaatgta tgctcttccc ctaagcttgt tgctattgtt
    17701 gcaagctcta aagaattcat taatcttcta ctagcttggt ctcttgtcaa tccattgata
    17761 ccatccttaa gtttaaatga aactacacct ccacctaaac cattcatttg agttttacaa
    17821 agctcatatt gaggatgaga ttttaatgct ggatacttta ccaattccac attctcttct
    17881 tcctctaaaa actctgctac tgctaatcca ttttcacaat gctttttcat cctcatatct
    17941 aacgttttca taccccttaa aatcatccat gcactcattg gtggtaaaga tgctcctgta
    18001 aaacaacata aacttggcca tctaactaaa tctattaatt cttttgaacc tgctactgct
    18061 ccccctaaag tatccccatg tccatttata aacttagtaa gactatgtat tactaaatct
    18121 gcacctaaat ctattggtct ttgtacaatt ggtgtcccaa aagtactatc aactatagct
    18181 aagcttttat tttcatgagc aatttctgct attgttttta tatctactaa gtctaatgat
    18241 ggatttaaag gactttctat ataaactatt ttagtatttg gtctcattgc ttcttttaca
    18301 ttttgtggat ttactgcatc tacaaatgta acttcaactc caaatttaga taacaactca
    18361 gacatgaata atttagtgtg tgaaaatatt ccatctgaac taactatatg gtcaccactt
    18421 tttaccaatg ctaatatagt agatgttatt gcccccatcc ctgatgtact agatatggca
    18481 ctttctgcat tttcaagcat agccaactta gcttctaact ctgtaagagt aggattacac
    18541 tctcttgtat acacatatcc ccatgtcata cacaactctt caaaatgctc tactgtcttt
    18601 gcagcaaatg ttgctgtttg acatattggt gtagccaatg cacctgttgt tgggtctgca
    18661 ctatgtcccc aatgtattat ttttgtctct aaatcttgat taatattgtt actcattttg
    18721 atttcctccc attttgactt atttatacaa cgttttccct gccaaatttc atcaatttag
    18781 cttagtctta atacattttt tcaagtatac ttttttattt gttataattt ctaaaaatat
    18841 gacacttatt ttgttttttt acagttctaa ttataaactc tatagtaact atagagtcaa
    18901 tatgtttttg atattttttt tacaatgttt aaaatagtca gtacaaaaat aggtatatct
    18961 tagaataact aaagtcatcc taagatatac ctatttttat atcacaatat aaataattac
    19021 atataagcat tagttttttt atcataaata gatttttcaa gatttatcat cttttcataa
    19081 atatattata gttaaatatt ttaatattac ctaacatcta caataaaata tactcttaaa
    19141 ataaaattat ataattaaaa atactctata aaagctaaaa agtttttcta ttcgctacat
    19201 ctaaaaataa ttagatagag gtataaatgt atttagttta tttatacctc tagtctttta
    19261 taaattatat ctctactaaa ttgatttttt agcacgaata agtgtgctct tggagatacc
    19321 agtcatcttc acaacctctc tatatggctt agaatttaat aaccccaatg catattgtat
    19381 ctgttgattg ctgtatttct ttggcctacc atctttaaag tcctttttct ttttagcaaa
    19441 ttcttttcct aattgagtac gttctattat catatttctc tcaagttctg caactgcaag
    19501 taatgtagtc aaaaagaatt tacccattga agtattttct aaaaggccta tatttaaaat
    19561 atgaacactt acttctttag caaataaacc ttctattagt tgtattcctt ctgatgtact
    19621 tctagctagt ctatccagct tagttgcaac aagtaagtct ccctttttta gagatgatat
    19681 aattttttca aatttaggcc tgtttgtagt agtgcctgta taagtttcct ttattatttt
    19741 agcatcatta tatttattca aaatttcttg ctgttgctga tacaaactgt tgttgtctgt
    19801 ttgatttttt gtacttacac ggcaatatcc atatataata atcatcactt cctaacataa
    19861 agattttgta cagaagttac ccagaagctt gtttttactt atctttatcc attttactaa
    19921 aacgattttt gggtgtcaat actgttaact tttgacacca taataattcc tttataattt
    19981 gtttgactat gtcaaaaatt accaatataa tgaaattaat gagtttatac aaattggagg
    20041 aaataatatg aatagtctgt taaaagaagc aatagatgaa ttaaaaaaca tccattgcgg
    20101 ggaagttttt ttattaaaag aattgttcaa aggctatgaa tggaacaggt tggagatgaa
    20161 tatcagattg aaattaggaa aacttttttt gtatgaagtg gtaactaatc ccaatttaaa
    20221 tgtagaggtc atcaataaaa actctgctta tcagcaaatg tataaaaaaa aatagtgact
    20281 taaatgtata taatagtata atcttcttat tgattcaaaa gttaaaactt ttaatacaaa
    20341 acaatcattc tattttaaca tttatcaata tgtctaaatt tatataatta acacatacga
    20401 atagtattgt ttaaatcaca ttatttaaga tagataaatc ttaaccctac tccagcataa
    20461 atactaaaat agggcttaga attatctata tttttatccc ataaaatgct tagctcttcc
    20521 tcttgattga acatatatat ctggggaaat acaatagaag cgtaaattta taaaatttcc
    20581 aaagtcagaa aacttcagtt caaacttagg tataccaaaa ctttcaggtg ctatttcgtc
    20641 aacgccaaaa tagatgataa ttccattatc tgtaagataa aatgcttggt cttcaggtat
    20701 aactaactca acattagaat aatacatttc tctattttca tttatttgag atttaatgta
    20761 atcagtaatt atattaatat aatcaactcc atctctaaaa atgtcattaa gtaaaagttc
    20821 ttttccagtt gtcaaatcta tattgtaatt attcaatgta ttgtatttag gcccatagtt
    20881 attagcaaac cccataaggt ttaatatcat actcagtaca taatttttat taaaagtaac
    20941 tgcgtaactg gtagataccc aatagctttg ttttggaagt gaattttgag aagctgcgtt
    21001 attatattct cgttcttctt cctgtaagcc atttttaaaa ttatttacag tcattcttac
    21061 agcattgttt atgttattta aaataactgg gtttacatac gtggattgat ttctaatatt
    21121 gtatataaca ggatacttta catcatatga aaaatactta cttctttcaa aatcttcatt
    21181 aaattgtaca tataatatat tatatgtaca ggtatttgta gattgataat tttccattaa
    21241 aatcctcccc cttttataaa aaaatcagat acaatataat atgcttaaaa cagtaataat
    21301 gttaatggta aatgtaaaga atagaaagta tctaaaacag caaaaaatga ctaattttgt
    21361 ggtataatac ataggattga gagttatttt ataggaggaa aaatatgtta ttattagcag
    21421 ataaatggaa agattatgaa cttatagata tgggaaatgg agaaaaatta gaacgttggg
    21481 gaagttatgt acttagaaga ccagacccac aggttgtatg gccaatggaa tctgaatggg
    21541 ctttatggaa aaaccctcat ggacattatc acagaagcaa taaaggtgga ggtcaatggg
    21601 aacacaaaaa aagatatcca gaacaatgga ctataaatta taaaaactta aagtttcaca
    21661 ttaaaccaac tggctttaaa catactggat tattcccaga gcaagcagct aactgggatt
    21721 ggatgataga gaaaataaag aaagctaaca gacctataaa agtgttgaat ctttttgcat
    21781 atacaggtgg agctactgta gcatgtgcat ctgctggtgc agaagtatgt catgttgatg
    21841 ctgcaaaagg tatggttaat tgggcaaaag aaaatataga attatcaggt cttaaaaatc
    21901 aaacagtaag atttatagtg gatgatgttg taaagtttgt tgaaagagaa ataagaagag
    21961 gtaaaaaata tgatgcaata ataatggacc ctccttctta tggaagaggt cctaaaggag
    22021 aagtatggca aatagaagaa aagttataca gttttgtaga tttatgtatg ggagttttat
    22081 cagataaccc tttatttttc ttaattaatt cttatacaac aggattttct ccaatagttc
    22141 ttgaaaatgt attgtctaca acaataggta aaaagacaaa tacaggagat atatacggtg
    22201 gggaattagg aataccagct tccagagatg gtaagatact tccttgtggt atatttggaa
    22261 gatgggagaa aaaataatga taaaagtcat atatgaagat aaccatttat tagttgtaga
    22321 aaaaccagtt aacatattgt ctcaaggaga taatactaat gataaagata tggtaaatct
    22381 tttaaaagac tatattaaaa aaaagtataa caaacctgga aatgtatata ttggtttaat
    22441 acatagattg gatagaccag taggtggagt tatggtgttt gcaaaaacat caaaagcagc
    22501 atctagattg tctgagcagg taagaagtaa gactttcaaa aaaacttatc tagctgttgt
    22561 tcatggcaag ataaaatcta actcagatat actaaaagat tttttatata aaaataaaaa
    22621 aactaatatg gtaactgtag tgaaaaaaag ccataaagat gccaaagaag ctgaacttaa
    22681 ctataatgta ttagatttta aagaaaatct aagtttagtt caagttaatt taaagactgg
    22741 tcgttctcat caaataagag ttcaatttgc aagcagaaaa catccattat acggagacca
    22801 aagatatggc aaagaaataa ataagattgg acaacaaata tctctttggt ccaataagat
    22861 agaaatttgc catcctacta caaaagaaaa aatggaattt acatgtcatc cacctgacaa
    22921 atatccatgg aatatatttt aaatctcaaa tgaggtgatt atatgagtaa aaaattttca
    22981 ataggagaaa tgtctaaact tcataaaata agcatacaga cactaaggta ctatgaccaa
    23041 atagatttat ttaaacctgt tcatgttgac caagaaagca attacagata ttactcaatt
    23101 gaccaatttt cacaattaga tattataaaa tatttaaaat atttaggtat gcctttaaaa
    23161 gaaattaagt caaagcttga tgaaaataat gaagaaattc taaaattact aacaaataaa
    23221 attaatatag tggatgaaaa aattaaagaa ttagagctta taaagaaggt actaagcaca
    23281 aagaaagaaa ctatggaaaa aggtatgaaa gtagatgaag ttggtaaaat agtgagaaaa
    23341 catattccac gaagaagtat cttatctata gagtatgaag aaggattaag tagtgaagaa
    23401 actatggaac tttccagaag acaaatagca aatatattag aagataatat atctgtgttc
    23461 tatggtggag taagtggact tgtatctata gataaatttt taaaagaaga taaagttatt
    23521 tatgacaata gttttgttac tgttgaaaga gacttatttg atataaaatc acaaaaacat
    23581 ataacagaaa tttcatctgg tgattttatt tgtatgacat ataaagggcc ttacaaagaa
    23641 aattataccg cttttaagaa actggttgat tatgttgaat ataaaagaat acctattgaa
    23701 aattatatat atgaaatacc tataatagac cctctgtcta caaacaacga agaggaactt
    23761 ctaacagaaa ttcaaataca agttaaaaag agagaaattg acttaagatg tctagtgtag
    23821 taatctagtt tacttacaca tcttaatata gttgtctatt atcaacatat gatttttcta
    23881 gatagtgatt cctaacagtg agattttcaa aaaataggag gaaatatggc taatgctaat
    23941 tccctcctat ttttaattaa tccatatcat tttaattaag ccatgtcatc acgaagtgca
    24001 tcaataatat tttctttttt tatcttatta atagtataca acattgtaat aaatactata
    24061 aataaaacac taaatatact aattccaata ctaaaccatg gaatcacaaa atcaatatca
    24121 tctgtaacca ttactttatg aattagccat gaagaaatta ctgctatagg aagtccaaag
    24181 aacaatgctc tcatgccata aaaggcacac tcaaaattca tcatcttttg gaaatcatgc
    24241 tcagacattc ctacagagcg aagcatggca agttctctac gacgtaactt aatattagtt
    24301 gaaattgtat taaacacatt ggcaatcgaa atcagagaaa tcataattat gaaagtataa
    24361 gcaaaaacat tggcaataaa aatgtaatta cggttctcat ccatcattcc atacatattg
    24421 tacagattgt actcattcgt aactccctca ctctcaataa tttgctccat ttctgcaact
    24481 gactgagtag gatttttcga ttgaaagctt aaactttcaa ttcctgtaga aacaccagga
    24541 atctcaaact tatctttggc tgaataagga gccaatactc tgaagcttgc tttcttcaca
    24601 tctgaacttc tgattcctgg aggagaatca ggtggcacta ctttgacaaa tgaaatattc
    24661 acattttgtc tctcaggtat ctccaacttg ccattagttt caggagtgag gctaacattc
    24721 atagaagaac tgttgaaaat atcaataata ttattatcct ttgttaccat agaaacagca
    24781 atcagttttg cattttgtcc agtatattct tctgctggta atccaagact tttaataata
    24841 ttcagataag ttctatcatc aagaaattgc atatctactg gtaattcaag catttcactc
    24901 atagaatgtg aaccctcata gttcaaataa tcgtctgtaa gctcacttac tttggtaaca
    24961 catgaatagg tcataagttt ctgatacaaa ccttcgtaaa caccatttgc agtttttagc
    25021 ttatcgtaaa gcttcaacat ttcgttgtct ttcatacctt gtgtagaaaa aataatatcc
    25081 tggtcagtaa cctctgacct ctgatttgac atctgtttta ggtctgctac taaagcactt
    25141 gtagatataa atagaactat gcttaaaaca agcgacaata caatacttcg ataacgtttc
    25201 ttgtttcttt taaagttttt catagcaaga actccctcaa gaccataaac tcgctgtgtt
    25261 agttttgatg tcttcacaga tttagattca atttttacct catttgtctg acgaatacac
    25321 tccatcactg gtgtgttggc agcctttctt gctggtatgt aagcagaaat taagattgta
    25381 accatactta ccactgctgc aacgatgatt gcagggatag acaatgttaa tttcaacgga
    25441 acgtttacat agagaatatt tgcaaagttt ttagctatga cagaaatcac aagtccaata
    25501 ctgactatac cgattgcaac accaattggt ataccaatcg caccaatgca aattccttca
    25561 aatagcaccg aatttcgtaa ctgttttgct gtagctccaa cagatgaaag tattccaaat
    25621 tgatgtgttc gctcgttcaa tgacatgtta aatgaattat atattagaaa aattgagcct
    25681 agcatgatta tggcaagcac aatgccacca accgagtaca aaaacatatt gaacaaattg
    25741 ttatcagaaa cacctatgaa gcgcaacaca ttgtcattga aaatggaagc atggtcttta
    25801 gtgctacttg tgtaagagcg aatctgatgt ggatttttca atgtgacaaa aaggctaaga
    25861 ctgtcagtct tgacttgttt atcttctttg gttatcaagg tatatcctgg tgcagaagat
    25921 tcttcaaata cgggctttct acagataccc acaactgtat aagttttctt atcctgtggc
    25981 acaaaaactt cactcccagc agtgtatggg tcactctgac caagcttttc attttcactc
    26041 attcgtttcc ctacatccaa agaaatagta tcacctactg caaatttgac accaccatct
    26101 gtcgcaactt tacttgaaac aagaatctct ctactatttt caggtaatct tccagaaatt
    26161 aaagttatag gcaaagtatc aaaagcttct ttgctaaatc cagcaataaa aagatatggt
    26221 ttatctggat ttctgttacc ttcaagtgtt gcatagccaa tattttcaaa tgttgcagta
    26281 tttgcaactt catcattgac tctttgttcc tgtacaaaag aagaatccac atccaaaaac
    26341 tggacatgcc aatcaccata ttttataata gctccatttg tcatatagtt catcaaagaa
    26401 actccaaagg tagtaactgc tgtaatcata gcagctgaca gaacaactcc tataattgtt
    26461 acaagagttc gagtgcgatt ctttttcaat ccttgcagag caactttgtt aaaaatgttc
    26521 attaacgatt caccttcctc tcatcacgca ctacttttcc atctgaaata cagataattc
    26581 tatctgcctg taaagcaata ttttcatcat gtgtgacaat aatgagagtt tggtgatatt
    26641 tactatggct ctctttcagt aactggataa tctcttgtcc atttttactg tctaagctac
    26701 ctgtaggctc atcagcaagc ataactgctg gtgcattcat caatgcacga ccaatggcaa
    26761 cacgttgctg ttggccacca gaaagttgat ttggtaaatg tgtttttcgt tcttttaaac
    26821 caagtaattc taacaagtca tttaaccgtt cttgattgac cttacgctta tccataagta
    26881 taggcaatgt gatattttcc actacattta atgtgggtat cagattgtga aactgataaa
    26941 tcaatccaac ttgtcgccta cgaaaaatag caagtttttc attactttgg ccatatacat
    27001 cttgcccctc cagatatatc tttccacttg ttggtacgtc tactcctgca atggaatgta
    27061 gtagtgtaga tttaccagaa ccagaagaac caatgattgc agtaaactcc cctttttcaa
    27121 tagtaagtga gacatggtca agtgcagtaa ccttattttc attcttacca taaaccttac
    27181 ataaatcttc aatctttaaa aacgccatta tataagtctc ctttcatatt ttataaatat
    27241 atcatagaac tttcaactta catttaagtg acatttaaat gagagattcg tcactttgga
    27301 aaacgaataa caaatattgc accaccttgt gggtgatttt gtgcagtaat tgttcctcct
    27361 tgtctcataa taatcgtctt acaaagtgcc aatcctattc cataaccagc tgtgcttgaa
    27421 tttttcccac gataaaatct gttaaataga catggtaagt cttctttttt aaagcctgct
    27481 ccgttgtcat gaatagtaag ttgagtaaac aaaaagttgt cctcacaaat gatatcaatt
    27541 tttccattat cacccacact ctccatgcag tttttaaata tattttgaat tgcttctgaa
    27601 agccaattta aatcacccaa aatccttact ccttttggta tatcaatatg taaagtgata
    27661 ttgtgcagtt ccatgggaat caaaagttga tgaagtgcag aactaatcaa attattcaca
    27721 tcaatttgtt ctttttgaaa gactacaata cctgcatcta aacgtgataa ttttaaaagg
    27781 gaagtaatca gccagtccat tcgtataagt aattcctctg tttctcgtat caactctttt
    27841 ctctcatctt catcagaagt attctctaac agtgacaaaa taagagttac tgatgtaaga
    27901 ggagtgcgaa gctggtgggc tatgtcagct agtgagtcag caaggtgttc tttttctttt
    27961 ttcagtgcgt aattttgctc tctaatacgt aacgtcattt tagttatttc actttgtaga
    28021 atagaaagct caccctcatc tgattcagca atatacagat ggttagcatt atgaagcaca
    28081 agattaattt gttctgaaat ctgtgcaata cttttgtatc gatttttagt aaacacaaaa
    28141 aatgctattc caaaggtagt ggcagaaaca atagaaagta ttccagtcat aatactgatt
    28201 gcaaatccca gggctacagt gagaatagta attaataaga ataaaatagc aaattttcga
    28261 aactctctat ttcgaaacat aacttccccc caatctatac cctgtcccac gaacagtcaa
    28321 aattatttgt ggacttgaag ggtcatcttc tatcttctct cgcaagcgtt tgatgtacac
    28381 agtcaatgtg ttgtcattaa caaactcacc tgccgcatcc cacaattcat caagtaatct
    28441 taccctcgta ataatacttt taggattact aataaacacc aataacaaac ggtattctaa
    28501 agctgaaaga aaaacctcat tgccattctt tttcacaaca ccggttgctg tatctacata
    28561 aagcccacaa atttcaaaag ttgacccaaa acgcccactt tttcgtagtg ctgttctaat
    28621 tcgcgcaatc agttcacgtg gacgaaaagg tttagtaata taatcatctg cacccatatt
    28681 cagtccagta acaacacttg attcatcacc ggaagctgtc aaaaagataa caggaatgtc
    28741 ttgcttttct ttgatttctg tgcaaatcgt aaacccattt ccatcaggta aagaaatatc
    28801 aataagtgcc aaatcaaatt tattcttagc aatctctaca agtgcttcac ttcttgtgga
    28861 tacatgggtt actataaatc cttctgaatt aagcaaaaga ataagatttt tggcaattgc
    28921 tttatcatcc tcaactaaaa atatccgttt catttacttt catcctcctt tattttatta
    28981 gttttatata ttccagcaga gcaatagtac actactattt tacttatcat tacacaattt
    29041 tcagtagttt cttttgttct tatataatcc atgcataata cctccattga tttattatat
    29101 ttcttataac ataaatacac aagataagac aaaaaacata atgtaagtgc aagtttttta
    29161 actcactaac ttataaacat acactcctac taacactact ttcttgatga cacatcttac
    29221 aagcttatat tcatacatca atgaaaaatt aaatttatcc atttattaaa ataaaaggca
    29281 atagcttcta tagctaatgc cctttatctt aaaatgattt aaatactata caatttttat
    29341 aaatggctat aaataaactc gtatagaata taaaatttat ctacagtctt ttgttataca
    29401 aaatttataa cctcttatag aacaaattta ccactttgca aacttatcac ttttactcag
    29461 ctatattata aacttttaat ttatctttgt ttaaatgttt cttcttaact tctactaaag
    29521 cttttagcgt atccaaagat gtcattattt cagtagaaaa ttcaatggct gttcttctca
    29581 tcttaaatcc atctcttgta gagtcatttc ctttagttgg tgtatttatt actatatcaa
    29641 cttgtttatt tcttatagca tctaatatgt ttggtctagg ttcttcaatt ctatttacta
    29701 tatcagcctc tattccattt tctcttaaac tcttcgctgt tccttctgta gcaacaaaag
    29761 tatatcctaa ttctttcata tcttttgcta tctctataaa ctcatcttta tcatgattat
    29821 ttacagtagc aagtactact cctctttcat cagacatatg tctacctgct gccaagaacc
    29881 ctttatataa ggcttcttct aaattttctc ctacacctag gacttctcct gtagacttca
    29941 tttcaggtcc tagacttact tcaactttag ataatttaga cattgagaat actggtactt
    30001 ttactgatac taattttggc tctttgtaaa ctcctgtacc atatcctaaa tcctttaatt
    30061 tagctcctaa catacactta gtagccaagt caactattgg tactccactt actttactta
    30121 tatatggaac tgttctacta gctctagggt taacctcaat tatatataat tcattttgaa
    30181 attctataaa ctgtatatta accataccaa gcacattaag gtctaaagct atttttttag
    30241 tgtattctac tatcttttct tttatttcat cagatatatt ttgacttgga tacattgttg
    30301 tactatctcc agagtgaact ccagctcttt ctaaatgctc cattatacca ggtatcaata
    30361 tatcttcttt atcacatata gcatctactt ctatttctct accagttaga tatttatcta
    30421 taagtactgg atttttatgg tctctatcaa atgcatcatc caaatactga attagttttt
    30481 cttcgttata agttatttcc ataccttgac caccaagtac ataagatggt ctaactaata
    30541 ctggataacc taactcctta gcaatttcaa caccttcatt agttgtccat acaccttttc
    30601 cttttggtct atttatatct agtctctcta gtaaatcatc aaatttttct ctatcttctg
    30661 ctgcatctat atctctaaag tctgttccca gtataggtat atttttttca tgtaaaaact
    30721 tagccaattt tatagctgtt tgtccaccaa actgtagtat tacaccttct ggtttttctt
    30781 tttctattat atttaaaact tcttcttctg ttaatggttc aaaatacaac ttatcagatg
    30841 tatcaaaatc cgtacttaca gtttcagggt tattgtttac aattatagtt tctattccca
    30901 tttttcttaa agattttaca cagtgaactg aacaatagtc aaattctatt ccttgaccta
    30961 ttcttattgg accagaaccc aatactacaa cttttctctt atcactaact actacctcat
    31021 catattgttc ataagttgaa tagtaataag gtgatagagc ttcaaattct cctccacatg
    31081 tatcaaccat tttataaact ggttgtatat tatataaact tctcaattca tataattttt
    31141 ctgggcttat cttcattaag tcagatatac ctttatcaga aaatcccttt ttctttaatt
    31201 catgtaaata ttctttatct aagtcttcta tttttagaac ttttaacttt tcttcttgtt
    31261 ctactatcca tttaaattta tttataaacc acttatcaac accagttatt tctgatatca
    31321 tttctacttt atagcctctt cttatcattt cagctaagtc aaatagtctc tcatcatcag
    31381 gtactactac tctagccttt aattcttcta atgttctacc ttctgatgga gcatgaacca
    31441 atgaatattt tcctgtttca agtgatctta tacctttaag aatagcagcc tcaaagttac
    31501 ttcctatact catgatttca ccagttgcca tcatcttagt tcctaatttt ctattggcat
    31561 gtctaaattt atcaaatggc cactttggta tttttactac cacataatct aatgttggct
    31621 caaaacaagc ataagttttt ttagttactg cattttctat ctcatccaaa gtataaccta
    31681 aagctatctt agctgctact tttgctattg ggtatcctgt agcttttgat gctagggctg
    31741 atgacctact aactcttggg tttatttcta ttatcgcata ttctaaacta tgtgggttta
    31801 aagctatttg aacgttacat ccaccttgaa cctctattgc atttattatg tctattgatg
    31861 cctttctaag tagttgatac tcttcatcac ttagagtttg acttggagca acaactatac
    31921 tgtctcccgt atgaactcca actgggtcta cattttccat attacataca gttatacagt
    31981 ttccatttcc atctctcatt acttcatatt ctatttcttt ccaacctttt atactctttt
    32041 caagaagaac ttgtccaaca ggacttagct gtagtccatg tgaaagtatt tctcttaatt
    32101 cttcctcagt atcagctata cctccaccag ttccacctag cgtatatgct ggtcttacaa
    32161 ctactggata tcctatctta ttggcaaact caagacctgc ttctaaattt gtaactatat
    32221 cactaactat tactggttga tttatttctt tcattacttc tctaaataaa tctctatctt
    32281 cgcccttttt tatagattct atagatgttc ctataacttt tacattatat ttatctaata
    32341 taccagcatc atgtaattct acagctaagt ttaatcctgt ctgaccaccc atacctgcaa
    32401 gtaaactgtc tggtctttct ttttctatta ttttttctat aaattctatt gttaatggtt
    32461 ctatatatat tttatctgca atttctttat cagtcattat agtagctggg ttactattta
    32521 ctaatacaac ttcaattccc tcttctttta atgcttggca ggcctgtgtt cctgaatagt
    32581 caaactctgc agcttgacct attattattg gccctgaccc taatactaaa gttttcttta
    32641 tactatctaa tttaggcata actctttctc cttatctaaa caattttcac agttcttatc
    32701 ttcatcatct atacaatcaa ctttaattac tttattttat cttaagttca aatttactca
    32761 tcaatacatc tatttaatac atctatgtta attaaaccaa actttttgat ttaagttatt
    32821 cttgtttttt agttagctat tctaatgttg tttattttac taattctaaa aatttatcaa
    32881 aaatatagtc attatctttt ggtcctgggc aagcttcagg atggtattga acactgtata
    32941 catctagctt ctcatgtcgc attccttcaa cagtattatc atttaaattt atatgtgtca
    33001 ctttcatttg ttcaggaact tctgaaacat aataaccatg attttgagaa gttataaata
    33061 cttttccttc ttctaaatct ttaactggat gatttccacc tctatgccca aatttaagtt
    33121 tagcagtttt tcctccaaga gctaaagcta aaagttgatg tcctaagcat attccaacta
    33181 taggtttttt accaataaga gcttttatat tttctataac atcttctaag tcttctgggt
    33241 ctccaggtcc atttgacaag aatattaagt cagggtttat actcaataca tcttctggag
    33301 atgttgtagc tggaaatatt gttatatcac atccacgagc tataaatgat cttaatatat
    33361 ttctttttac tccaaaatcc ataacagcca cttttggacc atttcctttt atatgctcta
    33421 cttcttttct tgtaacagtt ctaactgctt ctgtatttga aaacttatcc aatttatgtt
    33481 taacatcttc taatttactg tcttctaatg taattatacc tttcattgtt ccattatttc
    33541 taagtatctt agtcaaagct cttgtatcta ttccttcaag tccgataact ttattttgct
    33601 ttaaatattg gtctatatca atttcacatc taaaattact tggagaatca cttttctccc
    33661 ttactatgaa tccctttact tgaacttttt cagactctgc tgatgataaa tttataccat
    33721 aatttcctac aagaggataa gtcatagtaa ctatttgacc atagtaagaa gggtctgtta
    33781 aaacttcacc atatcctatc atcgaagtat taaatactac ttctcctaca ctttcttcta
    33841 aatatccaaa tgcctttcct ataaaaactg ttccatcttc taatattaac cttgctttca
    33901 tactacagta cctcctataa ttctctttag acaaactaaa gaacattaac taaatataag
    33961 cttttaaata tctatatcta tttttcactt ttacattcta gttttatact tatttacatt
    34021 tattttttat ctttttctat tatactacaa atttcttaaa aaaaagaagt tatctcaaaa
    34081 gtaaaaactc ctagaaaaaa taacctcttt tttttattta ataattaaat tcttaaacta
    34141 tacaatcaac ttaatttcta ttcagctata ttgtaaactt ttaactcatc tttatttaaa
    34201 tgtttcttct taacttctac taaagctttt agtgtatcca aagatgtcat tatttcagta
    34261 gaaaattcaa tagctgttct tcttatctta aatccatctc ttgtagagtc atttccttta
    34321 gttggtgtat ttattactat atcaacttgt ttatttctta tagcatctaa tatgtttggt
    34381 ctagattctt ctactctatt tactatatca gcctctattc cattttctct taagctatta
    34441 gctgttcctt ctgtagcaac aaaagtatat cctaattctt tcatatcttt tgctatctct
    34501 ataaactcat ctttatcatg attatttaca gtagcaagta ctactcctct ttcatcagac
    34561 atatgtctac ctgctgccaa gaacccttta tataaggctt cttctaaatt ttctcctaca
    34621 cctagaactt ctcctgtaga cttcatttca ggtcctagac ttacttcaac tttagataat
    34681 ttagacattg agaatactgg tacttttact gatactaatt ttggctcttt gtaaactcct
    34741 gtaccatatc ctaaatcctt taatttagcc cctaacatac acttagtagc caagtcaact
    34801 attggtactc cacttacttt acttatatac ggaactgttc tactagctct agggttaacc
    34861 tcaattatat ataattcatt ttgaaattct ataaactgta tattaaccat accaagcaca
    34921 ttaaggtcta aagctatttt tttagtgtat tctactatct tttcttttat ttcatcagat
    34981 atattttgac ttggatacat tgttgtacta tctccagagt gaactccagc tctttctaaa
    35041 tgttccatta taccaggtat caatatatct tccttatcac atatagcatc tacttctatt
    35101 tctctaccag ttagatattt atctataagt actggatttt tatggtctct atcaaatgca
    35161 tcttgtaggt attgagataa tttttcttcg ttataagtta tttccatacc ttgaccacca
    35221 agtacataag atggtctaac taatactgga taacctaact cattagcaac ttcaatacct
    35281 tcgttaagtg accatacacc ctttcctttt ggtctattta tatctagtct ctctagtaaa
    35341 tcatcaaatt tttctctatc ttctgctgca tctatatcat caaaatcagt tcccaatata
    35401 ggtatatttt tttcatgtaa aaatttagcc aattttatag ctgtttgtcc accaaactgt
    35461 agtattacac cttctggctt ttctttttct attatactta aaacttcttc ttctgttaat
    35521 ggttcaaaat acagcttatc tgatgtatca aagtctgtac ttacagtttc agggttattg
    35581 tttatgatta tagtttctat gtccattttt cttaaagatt ttacacagtg aactgaacaa
    35641 tagtcaaatt ctataccttg acctattctt attggaccag aacctaatac tatcaccttt
    35701 ttcttatcac taacaactac ctcatcatat tgctcataag ttgaataata gtaaggagat
    35761 atagcatcta tctcacctgc acaagtatca accattttat atgctggttt tatattgtat
    35821 agacttctca attcatataa tttttctgga cttatcttca ttaggtcaga tataccttta
    35881 tcagagaatc cctttttctt taattcaaga agatagtctt tagttaaatc ttcaattttc
    35941 ataactttta atttttcttc ttgctctact atccatttaa atttatttat aaaccattta
    36001 tctatacctg taatttgttc tatcatttct actttatagc ctcttcttat catttcagct
    36061 aaatcaaata gtctctcatc atcaggtact acaactcttt tctttaattc ctcaatgctt
    36121 ctctcctcag atggtgtgtg aactaatgaa tattttcctg tttcaagtga tcttatccct
    36181 ttaagaatag cagcctcaaa gttacttcct atactcataa tttcaccagt tgccatcatc
    36241 ttagttccta attttctatt tgctttttta aatttatcaa aaggccattt tggtattttt
    36301 gccaccacat aatctatagt tggttcaaaa caagcataag tttttttagt tactgcattt
    36361 tctatctcat ctaaagtata acctaaagct atttttgacg aaactttagc tattggatat
    36421 cctgtagctt ttgatgctaa agctgatgac ctactaactc ttggatttat ctctataact
    36481 gcatattcaa aactatgtgg attaagtgca aattgaacgt tacaaccacc ttgaacttct
    36541 actgcattta atatatctaa agatgctttt ttaagcattg cacattcttt gttacttaaa
    36601 gtttgagttg gagcaacaac tatactgtct cctgtatgaa ctccgactgg gtctatattt
    36661 tccatgttac atacaactat acaatttccc tttgaatctc ttattacctc atattctatt
    36721 tctttccaac cttttatact cttttcaatt aatacttgtc caacaggact taattgtaga
    36781 ccatgtgaaa gtatttctct taattcttcc tcattatcag ctataccccc accagttcca
    36841 cctagtgtgt atgctggtct tacaactact ggataaccaa ttgtaagtgc ataatcaaga
    36901 cctgcttgta aatctgtaac tatatcacta actattacag gctgatttat ttctttcatt
    36961 acttctctaa atatatctct atcttcacct tttttgatag attctactga agtacctatt
    37021 atctttactc catatttatc tagtatgcct ttttcataaa gttcaactgc taggtttagc
    37081 cctgtttgtc cacccatacc tgcaagtaaa ctgtctggtc tttctttttc tattattttt
    37141 tctataaatt ctattgttaa tggttctata tatattttat ctgccacttc tttatcagtc
    37201 attatagtgg ctggattact atttattaat acaacttcaa ttccttcctc tttcaaagac
    37261 tggcaagctt gtgttcctga atagtcaaac tctgcagctt gacctattat tattggtcct
    37321 gaccctaata ctaaagtttt ctttatacta tctaatttag gcataaattt ttctccttat
    37381 ctaaatggtt tttactatct gtaaataata ctaaatctat attaatgcta agaatttatt
    37441 aaatatacaa tctaaatctt cttttgttgt gtattctgga atgtattgaa cactatatat
    37501 tggtaattcc ttatgtctca ttccttctat agtattgtca tttaaattta tgtgagttac
    37561 ttctgtattt tctggcattt ctgaaacatt atatccatga ttttgagaag ttataaatac
    37621 ctttccagtt tctaaacatt taactgggtg attacctcct ctatgtccaa atacaagctt
    37681 tgaagtcttt cctcctaatg ccaatgctaa aatttgatgt cctaaaccta ttcctgtcaa
    37741 tggctttttg cctattaatt tttttatatt ttcaactata tcatttatat cctctggatt
    37801 tcctgggcca ttagataata agattaagtc aggatttata tttaaaattt cttctactgt
    37861 agtcattgct ggtactatag ttatatcaca gttacaagcc ttaagagact ctagtacact
    37921 atttttaaca ccaaagtcta taactacaac tttagctcca gtacctttta tattttcaat
    37981 ttcttttctt gtaacatttt ttactgaatc tttgttacaa tgctcttcta atttagactg
    38041 aacatcttgt aatgatacat tttctaaagt tataattcct ctcttagttc cattgtttct
    38101 aataatttta gttaatgctc ttgtatctat tccttcaagt cctattacct tattttgctt
    38161 tagatatgtg tctatatcca tttcacatct aaaattattt gggttatcac ttttttctct
    38221 tacaataagt ccttttactt gcaccttatt tgattcaaca tcttctaaat ttattccata
    38281 gtttcctata agtggataag tcatagtaac tatttgtcca taataagttg catctgtcaa
    38341 tagttctcca tacccagcca ttgaagtatt aaatacaact tctccaatag cttcctttag
    38401 atatccaaat gcttttcctt caaatactgt tccatcttct aaaattaatt tccccttcat
    38461 gtaagctacc tcccaaatat tttatctaag cattttctat ttctcttaca atattaatag
    38521 ctgattctct tggattttct gcttttgtta taggtcttcc aacaactaaa taatgagcac
    38581 ctttttttat tgcatctgat ggagttacaa ctcttttttg gtctccaacc tctgctgatt
    38641 taggtcttat tcctgggcaa actgttataa aatcagttcc acatgcttct actattttat
    38701 ctacttcttg cgctgaacaa acaaccccat ctattcctga ttcttttgcc agtttagctc
    38761 tctttatagc taactcttct gttgtcatat tacatcctat gtcctgtaaa tcttggttgc
    38821 ttaatgaagt taaaactgtt actccaacta ctaatggctt ttctatattt aatctttctg
    38881 cttcttccct agcaattagt gcacattgtc tcattccttc catatctgat acatgtattg
    38941 tcattaacca aacattatct ctcactgcag ctttcactgc acttttcata gtatttggta
    39001 tatcatggaa tttaaggtct aaaaatattt ttttcccttt ttctttaaga taatctattg
    39061 ttttaccttt tgtggcaacg tattgctcta gccctacctt aaatatgtct acactatctt
    39121 ctaatctgtc tattagttct ttagctttat caaattcgtc agtatcaatt gcaactatca
    39181 atttttcttt accatttatc atttttacat ctccttttta ataaagccta aataatcata
    39241 aaaaaatcct cacaccaaaa gaggcataag gattttatct atacataact ctattcatta
    39301 gctatgagat atctttccca gtctctctgg actagtttaa aagactttat tatatttaaa
    39361 tttttatttt atactcatca aaaacctcta gaagatttac tagaggttat atactaacat
    39421 tatctataac cctttagtct ctctggacta ctttaaggaa tttagctgta atatttttct
    39481 ttatttatat aattttatgt atctatagga taatttaaag ttttatcttt tttataatta
    39541 aaccactaat tgctttttat gtcaataagt ctttgaatta ttcttcatct ttatcaaaca
    39601 attttttctc aaaatatgat tctgcattat atattgcagc aactggatta tgcccagtta
    39661 ctctatcttt gacaactaaa gttgttatag gagcttccat atatttcatg gctaaagtat
    39721 cgtgaccaac acataatcca agaattacat taaggtcaac cttagcttca tttaaaaata
    39781 aagcttgtcc tattggattg cacattacct catctgaaca ctttgatatt gtttgagatg
    39841 cttctagtcc aattgtactc ttaggcattg ccccattttt acatataaca gaaaatactt
    39901 caaacccatg atgttcaaat attttttgca ctgtttgcat ttctcttttt agtccaatac
    39961 aaaatgctat gccaatcttt ttataaccac actttttagc aaactctata atctctttta
    40021 gtctagtata ttgacaatac ccctctgctt caactaatcc agcattataa gctatttttc
    40081 tattctcttc ttcttcataa agttgctttg ctttttgttg tagttcaatt tctctagttg
    40141 gacatatctt cattaattta tccatatttc cattagaaca gcctctaaga ttacattttc
    40201 cacacttata catatccaat atccccttcc aaaattttat tcatcttgcg attcttcttt
    40261 ttctagagtt acattttctt cttgggtttc ttcttctggt ttcacatgct cgactacagt
    40321 tataaaatat gattttccta ttttattcct tataggaagt ttttcatatg aaacatctat
    40381 tttatttttt atacaagcta tatcaaaatg tcttaaggct acacctaagc taaccttatt
    40441 catatcttca cagtgtttct taggtctctt ttcaaataaa tgaagacctc gttcatcctt
    40501 atggaaatac cacggttgag aattttttac agatggagct cttcttgtca attctaagat
    40561 atctttccac tttctattcc tatttatctt atttatcata tcttttactg gctttctatc
    40621 aggtctagca tatctcgtcc taaacaactc ttcatttttt gctggatatc caaatgctat
    40681 tattatataa ggattttcta ttttgttttc atcatcttct tctgttttta ttccagctag
    40741 ataatctaaa tcatcttcct catcttcttc aaaattctta ttcccaatat ctacaaattc
    40801 caagatatct tctctcttta agtttccttc caaccagcaa gtagctattc ccaatgttgt
    40861 aaggcgcaaa actacacctt ctgtagcaaa tcctatattc tgtaaatagt cctcaccttt
    40921 gtctgatgta actactatat aatgaggtgc ctttacttta cattccttac ccatcaaaaa
    40981 atgtattata tgacctctat caacaacatg tgctttaata tttaaatctt catttaagta
    41041 ttctaaattt ttacaacttc tttttatttc ttccatcaat ggctttttta tctttttact
    41101 ggaaaaattt cttacagatt ttctataaaa aatggcttca taaagctcca tttatgccct
    41161 cctaactgaa atcttctgac gtataaactc tataaattta tataaatact ttatattttt
    41221 tatagtttta tttccttttt cctcctgccc tattttgaaa ttcataagaa tatctactct
    41281 agtttaatat agcattcaaa aggcttaaat tctaccttat caatgtctat acattagcat
    41341 aattttttta tttgattttc tatgctaatt taaataacaa cactagctat taacttttta
    41401 attaagcttt gccagaaaaa ttttttttca tttataaata tctatctcat tattatatta
    41461 taagtttttt tcggtattct tgtatagctt ttcactaaaa aagtattttt atttctactt
    41521 taatattatt atcaacaaaa aacatactgc ttaaataagt ttgttatcct cataatctgt
    41581 tttaattaaa atattttttt tatttctcaa tctataaagt ataaatattt tgaatatgac
    41641 ccaaaatcta agtaaagtta taatatttta taagttgttc aatattaaaa acataagtaa
    41701 tgttataata ctttataagt tattcaatat taaaaatata ggaggataaa tatgaattta
    41761 aatagaaatt tagaaaaata cgctgaatta gcaataaaag ttggagttaa catacagcca
    41821 ggtcaaattc tacttataaa gtcaccaata gaatgtgctg attttgcaag aaatgcactt
    41881 aaagaagcat ataaatgtgg tgctaaaaat gtttatatag agtggtctga tgaagaaagt
    41941 actcttatta aatacttata tgctccagat gaagcatttc atgagttccc caaatggaca
    42001 gcagaacaat atgtagatat agcaaaagaa ggtggggcat ttttatcagt ctatgcccaa
    42061 aatccagatt tattaaaaga tgttgaccct gaaagagttg caaattttca gaaggcatct
    42121 ggaaaagctt taaaagaatg gcgttcttac actctaactg ataaatgtaa atggagtata
    42181 gtctctgtgc caacaaaaga ttgggcaaaa aaagtgtttc caaatttatc agaagataaa
    42241 gcaatagaaa aactgtggga tgctatattt aaatgttcaa gagtagatgg tcaggaccct
    42301 ataaaagcat gggaagaaca taatgaaaat cttaaatcta aaatggactt tctaaataaa
    42361 aataacttta aaactttaaa atataaatcc tcaaaaactg atttgactct agacttgcca
    42421 aagggtcatg tttggctaag tggagcatcc aaagacccta atggaataag ttttaatccg
    42481 aatattccaa ctgaagagat ttttggaatg ccacataagt ttaaagtaaa tggaactgtt
    42541 tatagtacaa aacctcttgt ttatggtgga aacataattg acaatttctt cttaacattt
    42601 aaagatggta aaataataga tttctctgct gaaaagggac tagatacact agaaaaactt
    42661 attgaaacgg atgaaggctc tcattattta ggagaagtcg ctcttgttcc atacaactca
    42721 ccaatatcca atacggatat aattttttat aatactctat atgatgaaaa tgcttcttgc
    42781 cactttgcaa ttggttctgc ttataagact tgtctggaag gtggaaataa tttaaaagat
    42841 gaagaattag atgaacatgg tgtaaatgac agtttaacac atgtagattt tatgattggt
    42901 tctgctgata tggatattat tggtgagact tatgatggaa agcaaataca gatttttaaa
    42961 aatggtaatt gggcttttta acatatgatt ttaactaaaa agggctgatg gaagttatac
    43021 cagacttccc agcccttttt aatgttgatg ataaatattt tttatattaa ttaatctcat
    43081 tattatagat taattcctat tgttttaaac ataagtatct aaaacttata tttatattat
    43141 atataaaata tcctatttag taaaaccttt attttaattt atatgctaaa aatttaactt
    43201 tgctatttca acagcagact ttgcatcctt tgaataataa tcagcaccca tttcttcagc
    43261 gtattcttct gtcaaaactg cacctcctac aaataccttt gcatttatct cattatctct
    43321 cagtgcctga attgtatctt tcatactttg aacagtcgta gtcataagtg cacttaatcc
    43381 tactaatttt atatttctct ttttagcaac ttccactact tcttcaatag ggacatcttt
    43441 acctaaatct ataacttcat atccataatt ttctagcatt atttttacta tatttttccc
    43501 aatatcatgg atatcacctt ttactgtagc aactattatt tttcctttgg atacattatt
    43561 gctactttta cttaataaag tttcctttat tgtatttaat gaaactttta ccgtttctgc
    43621 tgattgaatc aattgtggta aaaatatatc tccactatca tatctttttc ctactttatc
    43681 aagagcagga attaaaatct catctaatat ataattttca tccttctctt ttaaaagatt
    43741 cagtgttaca ttttttgctt catcttttaa tcctctttca actaaaatat ccaagggcaa
    43801 atctttatca atctttgtag atgaatccga tttttttgaa ttatttatat tgctatattg
    43861 atttatatag tttatacatc ctttatctgt gttatttaat attttaaaag aattgatagc
    43921 ttccatcata ctatattcat ttggatttat aattgctaaa tcaagccctg cccctaaagc
    43981 taatgttaga aaagaagcat taagtgcttt cctatttgga agaccaaatg aaatatttga
    44041 aacacctaat atagttttta ctcctagtgt ctttaccatt gttatagctt ttatagtttc
    44101 tattgcttct tcttgttgtg ctgaaacagt taatgataaa cagtctataa atatatcttt
    44161 tggttttatc ccataagaaa ctgctctatt aactatcctt tttgctattt caaatctttc
    44221 ttcagccttt ttaggtatcc ccttttcatc aagtgtaagt ccaaccacac atgaaccata
    44281 ctttttaact attggtaata tactttctaa agactcctct ttgccattta cagagtttac
    44341 tattgttcta ccattataat atctaagtcc ttgctctaag gcctctacat tggaagaatc
    44401 aacttgtaaa ggtgtatcta ctactgcttg aatctctctt attaattttg gcattagttt
    44461 tttttcatca atctctggaa gaccaacatt tactccaagt atttgtgctc cagcatttac
    44521 ttgttctaaa cctaaattta tagcataatc aacattttca ttttttaatg cttcttgtag
    44581 agattttcta cctgtgggat tcaatctttc tccaacaact gtaggcgatt gtacttccac
    44641 aaattttgat ggtgaacaga ctacacattt atcaattttc tcgatacatc cctttgtaac
    44701 agaatttata ttctcagata tttcttttat aaaacttgga ttcgtaccac aacatccacc
    44761 tattatagta gcaccaactt caacgaactt tttaacccct tcaaaaaatt cttttgcatc
    44821 aacatcatat atagcctctc catcaactat atttggaaga cctgcatttg cttgaaccat
    44881 aacagggact gtagctcttg atgctatttt ttcaactatt ggtaaaagtt gtttaggtcc
    44941 taatgaacaa ttaactccta ttgcatctac acctagacct tctatagtag ccaccataca
    45001 ttctggcata catccagtaa aacttcttcc accttcatca aatgtcatag tacagaaaat
    45061 aggtaaatca gagttttctt ttgctgctaa tacagctact ttagcttcat ataaatccat
    45121 catagtctct attactatta catcaactcc agatttaacg ccttgtagta cttgtctttt
    45181 aaatatttca tatgctttat caaaacttaa agtacccata ggctctagca tttctcctat
    45241 aggaccaata tctaaagcta catatcttgg tttagtatta tctacatttt ctatagcttt
    45301 tctagccacc aaaacagcat tgtcaatcac ttcttctaca gtatacttac tatctaattt
    45361 tagttcatta catccaaaag tatttgtaag aattacattc gaacctgcct ctaagtatgc
    45421 tgtatgtatt tctataagtt tatctggatt ttgaagacca aatacttctg gattttcacc
    45481 taactttaac cctttttgtt gaagcattgt tcccattgca ccatcaaata ttaatatatt
    45541 atttttcaga tattgtctta tttccacaag agttcgctcc ttttctatat gtacagtttc
    45601 tatagttttt acaattttca cacgactttt ctttcttaga tttatttatt cttgtattag
    45661 aaatacctat aatagccact actgactttc tcggtatcat aattccatta gaagtaattg
    45721 ttagacctat ttgtttttga gcattcaaaa cgtttaatat atctatattt ttttctattg
    45781 gtaaatctcc atatcctggg ctatatcgca tagttataaa tttatcttgc tttaaaaaaa
    45841 ccttttctaa attattttga acaatgtcac acacttcttc tattgctgtt gttccacatg
    45901 aatcaattat tagtcctttt gttaaatttg aataagagtg tcgtcttatt tctttttcta
    45961 tatctatccc tatagtagct gccataatta cacactcatt acattctttt aaaagttcat
    46021 atacatcttt actctctaat gttaaatttg ttccctctaa ttctacaaca ttatctttat
    46081 ttattttaat aggataaatc ctagataaat atctaggatt tattttattt ttagttatag
    46141 ctacacattc atcaatagta tatttaaggt ctttatctat ctcttgacct ctgtattgta
    46201 aatatcttaa aacttcactt tgatttatgc ttatatcttc tcttccaatt aaattattct
    46261 ccatatatat ttaaagaaaa tcctttatct aaaacatctt ttgcatattc ctttgcccca
    46321 aataaagata agtctctgta gtttccacat tctatagctg tagctgctgg cattttatct
    46381 gattcaagaa ctttttttaa tgcttcttct aaaccaatct taactgtttt ggcatctaca
    46441 tctccccata gtattaaata aaatcctgtt ctacatccca ttggagataa gtctattaca
    46501 ccatctaatg tatctcttaa ataagtagct aaaagatgct ctaaaccgtg catagcagca
    46561 gttccaaaac tttctacatt tggctgtaaa aatctcaagt caaatttagt tactttatct
    46621 ccctttactc catcaagtac actacacttt cttacaaaag gagcttttac ttttgtatgg
    46681 tctagcttaa aactttctac tttttccatt atttaatcct ccattatact ttaaaatttg
    46741 ttacattaat tctaaaaaaa actcttccta tctattattg ataagaagag tatattattt
    46801 caagtcatct catcgttgtt agcaggacca cctgataaaa ggttggtata ggatcactga
    46861 gctaactctc tcccctaact cttgataagt atcttattaa actgacttaa attatatatt
    46921 acttttttat ttttgtaaac actttattgt tataatattt atatcacata atcgtacttt
    46981 tattttataa ctaagctgat tgtattattg gcagttgtac ttcaaacaca gtttgatatt
    47041 tatcgcttga aacagtaatt tctccatcat gtaaatttac aatatttttt gtaatcgcaa
    47101 gacccaatcc agaacctcca acatttctat ttctcgattt ttcaactcta taaaatctat
    47161 caaatatatt tggtaaatct aacactggaa ttggttcccc ataatttatc acttttacaa
    47221 ccgccatatc ttcctttttc tctgtgacta tatctacata atgcccatct tttccatatt
    47281 tcacagcatt agttataaga ttttcaaatg ctcttaccaa tttatttgga tcagctttta
    47341 caattaattt ttcttcatta aaattaattc tactaaccat aaattcttgt ttaaaataaa
    47401 tttcaaattg agatactact tgacttaata actctactaa atttatttct attttgttta
    47461 attttattgt attattttgc attttagtca attcaaacaa atcatttata agaacattta
    47521 aatttttcga tttttcatat gcaatatcaa cataatacat catctgaact tcatctttat
    47581 acttaccttc ttctatcact cctaaataac ccattatgga tgtcaaaggt gtccttaagt
    47641 catgtgacac atttgttatt aaatctgttt ttgtctgctg agcttgtctc tcttcaatag
    47701 ttatatttct aagttgatgg actatattat tgattttatg tgctagttca tcaatatcat
    47761 ccttttcttt atcctttaat atatctaagt catactcaat atctatactt ttttctaagt
    47821 taccttcatc cattaaattt acagcacttt taatgatttc taatttttga ttttttctat
    47881 tagtctttct tataaaatct acaatttgct tatttctctt gtacgatatc atggaataaa
    47941 ttgctaatga tgtgattgta aataaaaatg gataaaataa actctctcct ataagacttc
    48001 tgagatctct taactgatat acaagttgat taattacaga tatcccacta ttgaaatata
    48061 atgattttat tatatacata cttgttaaaa taagcattga agttaaagca cagcttatta
    48121 taatatctaa tatgggtcga aacatatgat ttaataaact tttatttttc aattttatat
    48181 ccaactcccc atacagtatg aattattttt tctccatctg tatatttttc aattttatct
    48241 cttattctgc tcatatgaac cattacagta ttattagatt ggtaatattt ctctttccat
    48301 accttttcaa atatttcttc tgtactatat actctgcctt tattatttgc tagtaaatat
    48361 aatatatcaa attctcttga tgtcaaaatt atttcatttc cagccactgt tacactatgt
    48421 ttttccttat ctataattac tactccaacc tttatgacat ctttatcttc attattagca
    48481 ccactaaaat aatatgctct tctaatcagc gacttcactc tcacagtaag ttcaagtggg
    48541 ttaaatggtt ttgtcaaata gtcatctgca ccagtcatta tcccttgtat tttatccatg
    48601 tcttctgatt ttgcacttaa cataagtatt ggtatattca aactttctct aacttttcta
    48661 caaacttcta tcccatccat tttaggcatc attatatcca atatcattaa atgaatattt
    48721 tcctttttta aaatatctag agcctctttt ccatcttcag ctttaattac attatatcca
    48781 ctatttaaaa gatatatctc tataaggtct cttatttcct tttcatcatc cacaacaaga
    48841 attgtattat tcatttttac acatcctaac ttaatctttg tatatagctt tattcatata
    48901 aaattatact atattttagt tagtgtaatc tataaattta ttaatttcta aatttccaat
    48961 ataatacaaa ttatttacac atttatatta tttattttgt aaatattctt ctaaagttaa
    49021 tccttttgaa taaatttcct cggcagcatc cttaccaaca tatctaatat gccatggttc
    49081 atatgctgta cctgttatat cttctttacc ttcaggatat cttattataa atccaaactt
    49141 gtgagcattt tctgccaacc atttagcttc ttttgtactt ccaacaaacc atctttctgg
    49201 atttgttaaa tcaatacaaa gtccagtttg gtgctcactg taaccaggct ttgctacata
    49261 tgcatctgcc ttttctcgtc cctgagattt tacccttctt gtataagtat ccagttgagt
    49321 atcataagat ctgtatgctg aagaccctaa aaactgtatt ccttctgaat tagcttgctt
    49381 aactaaatct tcaactgcct ttgcaggttc tcctgccatt tgtttttctt cctctgttgc
    49441 ttcttcaaca aaaggtatgt ttaccttagt aatattttca ggagtatagt ttttgctaat
    49501 tccatttgtc ttgtttacca ataatatatt tgatatacta tttgagtgat ttttattttg
    49561 agaatttgcc tcaacatctt gttctgaatc atgttgagca gctactattg gatcgttatc
    49621 tttcttaagt aatctatctt tagatataaa tacacttata aatactacta aaataatggc
    49681 tcctattaat ttaaattttt tcataattaa atcttctcct ttttgttatg tttgctataa
    49741 tgttaatttt agagtataag acttaagtat tttataagta aatcttaaat aaatcttaaa
    49801 tttaatattt ttaaaggatg gtgataaaat gtctatacaa aaacttctaa gtaaagctcg
    49861 taaggctata caagattttg atatgataca agaaaatgat aaaattgcgg ttggactttc
    49921 tggtggaaaa gatagtttaa ctttacttca tatacttaaa agttatcaaa gattttctcc
    49981 acaaaacttt gaattgatag ccataacatt aaatactgga ggtgttgata attctccact
    50041 agataaattg tgtaaagaaa taaatgttcc tttttatgaa tttcaaactg acataaaaga
    50101 aattgtattt gatataagac aagaaaagaa tccttgtgca ttatgtgcta atttaagaag
    50161 aggtgctttg aacgataatg ctaaaaaact tggatgtaat aaagtagctc ttggtcatca
    50221 taaagatgat gcaattgaga catttttaat gtctatgttt tatgagggta gagtaaattg
    50281 tttttcccca aagacatacc tagacagaca ggatttaaca gttataagac ctatggttta
    50341 catagaagag tatatgacta agaaaatttc aaaagattct aactatccta ttatcacaaa
    50401 tccctgccct gcaaatggtc atactaggag agagtacata aaaaatctta ttgctaattt
    50461 aaataaagag atgcctgatt ttaaaagaaa tgtatttggt gctttaaata attctgagaa
    50521 attgtttata tgggataaag agaagataaa aaattttaaa taataattaa aatttttaaa
    50581 taaaaaagca agattgtatt aattgtaaat aatctttat
//
LOCUS       DAEPXW010000017        49699 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.017, whole genome shotgun sequence.
ACCESSION   DAEPXW010000017 DAEPXW010000000
VERSION     DAEPXW010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49699
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.017"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(13..609)
                     /locus_tag="KRM55_000982"
     CDS             complement(13..609)
                     /locus_tag="KRM55_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBH1593239.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAM
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(649..1452)
                     /locus_tag="KRM55_000983"
     CDS             complement(649..1452)
                     /locus_tag="KRM55_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBH1593240.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(1488..1928)
                     /locus_tag="KRM55_000984"
     CDS             complement(1488..1928)
                     /locus_tag="KRM55_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBH1593241.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(1941..4043)
                     /locus_tag="KRM55_000985"
     CDS             complement(1941..4043)
                     /locus_tag="KRM55_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBH1593242.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(4304..6007)
                     /locus_tag="KRM55_000986"
     CDS             complement(4304..6007)
                     /locus_tag="KRM55_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBH1593243.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(6033..6992)
                     /locus_tag="KRM55_000987"
     CDS             complement(6033..6992)
                     /locus_tag="KRM55_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1593244.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(7128..7646)
                     /locus_tag="KRM55_000988"
     CDS             complement(7128..7646)
                     /locus_tag="KRM55_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBH1593245.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFRVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(7689..8174)
                     /locus_tag="KRM55_000989"
     CDS             complement(7689..8174)
                     /locus_tag="KRM55_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBH1593246.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(8171..8788)
                     /locus_tag="KRM55_000990"
     CDS             complement(8171..8788)
                     /locus_tag="KRM55_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBH1593247.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(8853..9215)
                     /locus_tag="KRM55_000991"
     CDS             complement(8853..9215)
                     /locus_tag="KRM55_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH1593248.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(9959..10456)
                     /locus_tag="KRM55_000992"
     CDS             complement(9959..10456)
                     /locus_tag="KRM55_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH1593249.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            complement(10631..11542)
                     /locus_tag="KRM55_000993"
     CDS             complement(10631..11542)
                     /locus_tag="KRM55_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH1593250.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            12493..13344
                     /locus_tag="KRM55_000994"
     CDS             12493..13344
                     /locus_tag="KRM55_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH1593251.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            13348..13818
                     /locus_tag="KRM55_000995"
     CDS             13348..13818
                     /locus_tag="KRM55_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593252.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            13831..15141
                     /locus_tag="KRM55_000996"
     CDS             13831..15141
                     /locus_tag="KRM55_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1593253.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            15353..16099
                     /locus_tag="KRM55_000997"
     CDS             15353..16099
                     /locus_tag="KRM55_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1593254.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFAENKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            16461..18002
                     /locus_tag="KRM55_000998"
     CDS             16461..18002
                     /locus_tag="KRM55_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH1593255.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            18037..19143
                     /locus_tag="KRM55_000999"
     CDS             18037..19143
                     /locus_tag="KRM55_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1593256.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(19474..20760)
                     /locus_tag="KRM55_001000"
     CDS             complement(19474..20760)
                     /locus_tag="KRM55_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1593257.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(20883..23981)
                     /locus_tag="KRM55_001001"
     CDS             complement(20883..23981)
                     /locus_tag="KRM55_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1593258.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISIMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            24706..24858
                     /locus_tag="KRM55_001002"
     CDS             24706..24858
                     /locus_tag="KRM55_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593259.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHSSAFSGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(25150..25854)
                     /locus_tag="KRM55_001003"
     CDS             complement(25150..25854)
                     /locus_tag="KRM55_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593260.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(25845..27452)
                     /locus_tag="KRM55_001004"
     CDS             complement(25845..27452)
                     /locus_tag="KRM55_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBH1593261.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(27706..28884)
                     /locus_tag="KRM55_001005"
     CDS             complement(27706..28884)
                     /locus_tag="KRM55_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593262.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(29110..29604)
                     /locus_tag="KRM55_001006"
     CDS             complement(29110..29604)
                     /locus_tag="KRM55_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1593263.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(29605..30366)
                     /locus_tag="KRM55_001007"
     CDS             complement(29605..30366)
                     /locus_tag="KRM55_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1593264.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            31088..33922
                     /locus_tag="KRM55_001008"
     CDS             31088..33922
                     /locus_tag="KRM55_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1593265.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            33965..35209
                     /locus_tag="KRM55_001009"
     CDS             33965..35209
                     /locus_tag="KRM55_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1593266.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(35624..37366)
                     /locus_tag="KRM55_001010"
     CDS             complement(35624..37366)
                     /locus_tag="KRM55_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593267.1"
                     /translation="MKKTINNNLFRILNIIVYKNKTKLIVSFIMVFIIAGVNIVIPQL
                     IRCIIDDGIGNKNIFLLINLILIYIFIRILSATFDVILSYLYTSIKNKVTINLKVKLL
                     NHISKLSGRYYSSKKTGNILSIMESDIFMIENFGAEIIFDIIVNVFTAIISLIFLINL
                     QFDLFLVVLFLQLILTFSQNKMTKLISKKISEIRSDSGSLSNLIQEYVSNIMDIVILN
                     SKKNFFNKYLKRERDLIKKDLNLNIIMSSNIAISQILTGLITILIYGIGGYKIINNKM
                     TMGELIAFQQYTGMLIGPCIAIVRANTRIAQSKVSINRVFSVIDEKIDIKVDNNGYRI
                     DNSEIKKIDFKNVSFRYGEDLNLVLNDINLQFEKGEVTGIVGGSGCGKSTITNLIYRL
                     WDINEGDILIDGVNIKDINLKSLRNNIDIVTQDQFVFDDTIKNNIVLNNKISDKELDE
                     ILEVTCLDDFIKNLDKGLDEVVGEKGVKISGGQKQRISIARALVSNKKVLILDEATSA
                     LDNISQKEILNNLKEYIQDKIVIIIAHRLSTIKSADNIYVLDKGRVIESGNDAELLHK
                     DGLYNKLVETADFA"
     gene            complement(37350..38024)
                     /locus_tag="KRM55_001011"
     CDS             complement(37350..38024)
                     /locus_tag="KRM55_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593268.1"
                     /translation="MKILKVKDLKKIYGKYENEVRALDGIDLDIEPHKFTAIVGASGS
                     GKSTLLHCVAGLDKPTLGNVYLDDVDLYTLNDDKLSEIRRQEFGFIFQSYNLIPVINV
                     YDNIVLPVLLDGKKEDKEYVMRLINKLGIEKQIKKYPNELSGGQQQRVAIARALANRP
                     SVIFADEPTGNLDSKTTNEVMNMLEWCVKEYKQTLVMITHNDNIAKTADRIITIKDGK
                     IDEKNY"
     gene            complement(38061..39050)
                     /locus_tag="KRM55_001012"
     CDS             complement(38061..39050)
                     /locus_tag="KRM55_001012"
                     /inference="COORDINATES: protein motif:HMM:NF012311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH1593269.1"
                     /translation="MTKVRIAVLDTGLDVNDDDINGNYVYDSNFQLKDLGGKEINDIN
                     GHGTFVSKTILNISKNTQIYPINIFNDSGKTSSLNLLSTLSKLTMSDIQIINISAASI
                     NSMYEKELEKVCNILNSQGRFIICSKHNKYEDKESIPTIFESVIGVVGNENIYKNNQY
                     IYEPENKIQMYANSKDNFIKFKDKVTHFGKNSKACAVATGIVANILKNNPYIKFNELE
                     EILIQKSKSKEDLKIENLNTPSYKSNLIRLDIARKIINVINRNFSKIKIDFEFVSEYS
                     LFNNFTCIGNYNAYNFLTILNKEFNISIDYKEVYLYQLENLDMAVDLIYENLI"
     gene            complement(39098..40342)
                     /locus_tag="KRM55_001013"
     CDS             complement(39098..40342)
                     /locus_tag="KRM55_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1593270.1"
                     /translation="MNSSNKYFLDCICEKIINNNQVILSNKVNGRWVKIPIECYEVLK
                     YSVDNALQLGNLYDVFQENEDKKYYERVIDKLEYIGLLSDSILSEFRLERINKISFSP
                     TNRCNLSCDYCCVDSKIDNNDYLDTSQVRKVIDNIVKLNPRILTITGGEPLMRNDFLE
                     LLDYIKEKFKGKIILSTNATLIKEKQIDDIINGLYAIEISLDGYDELSCSEVRGKGVF
                     CKVLNVIRLIKLKKFENVGLSMVVGKNNEKDIEKFNKLNEDLGTTPIIRNFMNIGRGN
                     ENYSKYLNDKLDIDYICKDDYVDESSLCSNMCKAGVNQISIDHKGDVYPCPNLEYKDL
                     KIFNILEFNENILERILNREMDIFNIFDKLKPVNIESCKECKVNLFCTTCPSKIYTLK
                     NNKKMFDANCKKMKNILEPILW"
     gene            complement(40384..42930)
                     /locus_tag="KRM55_001014"
     CDS             complement(40384..42930)
                     /locus_tag="KRM55_001014"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593271.1"
                     /translation="MINIKLAVSYLKRQKGKTLSLILSIGIAVMLVFSLSVINESQGQ
                     SDINHAYKNSGDYHAFYEDINSDIVKELNGEEDIKEFNDVLKFGEIISKDNGASLNLC
                     SYNKDFLDSTRYKLVKGREPRTSNELVIEQKVLDKMELDVKLNQTIDFQIVNEHINKN
                     NENSIYSKDKQFKIVGILSKSDEYYENLNKYKVRAFTYSNNGKDIVPYELITHMGTLK
                     LNTKDLDSQKVVNLGRKYKLTSNQFYPNTEVSMSMYMKNISKKTTYSIKQSLLPLLCA
                     TLVIYNMFNIIILDMTKQIGLLRAVGASKRNIRQVFFIQSIVVLSVGIVIGLLGGIVF
                     SYLGLMIVYDKSAELTINTNSIIESIIMSIIAVILASVVPIYKAGNLSIIDAIKKTDK
                     LNYIPRLLLLKSHKKVVGIINEIAFKNIFRNKVTSIIIIITISLCGVLFIGRLTSTKF
                     IYGKESDSANITSKSYGNFDIYLGYSPINANYTFSKYDNSLLNEIKAIEDVTDVEPNI
                     YLKGYLRNADLEEDYLDELKRTEINNNNESTVLIRGYNKELLNNIDKYIDKGENVYSY
                     TDRDYKNVLLVNNFYSRIKLSNNTQIIKSPKIGDLIDIKIPVYKDGEYKYINTKVRIA
                     GIMKNSYISEQDGESQSGGIQIIFNEKDLKELTGISDYNKVFVKIKKETDKKVIKEIN
                     NIIEKSGFSDIEGRYVRNHFGDHYNKSSYKLAMICVFGVLLISSINIIFIVRSNIIVR
                     LSEICTFRAIGMSKKNVKRMLIKENMIYGVLSMIVAGIISSFNYYKIVSETNKLNQQV
                     YGINNSIKFEIPIYEILIFGSISVFVCVIAVYFSNKMINKLSIVSGIKEN"
     gene            complement(43138..43299)
                     /locus_tag="KRM55_001015"
     CDS             complement(43138..43299)
                     /locus_tag="KRM55_001015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593272.1"
                     /translation="MIHIKKIEEKIELQDVEVQADPCKWYYDKHGIISQIDCMVDCAG
                     STPKGTVAY"
     gene            complement(43355..44371)
                     /locus_tag="KRM55_001016"
     CDS             complement(43355..44371)
                     /locus_tag="KRM55_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1593273.1"
                     /translation="MKFTIFVTEDCNLRCTYCYEGNDKKKENMSYETADKTIDFICNK
                     ELESNSDYTTIVLHGGEPFINFDLIKYIHRDLVDRLSDKKILFDITTNGTIINDEIIE
                     FIAKNVKNISISIDGKKNIHDINRIDANGVGTYEKVMENGKRLIDKGIYVRARMTYNS
                     NTVKYLYESVYDIAKQGFKNIAPISDFMDKNWDNSHIKILNEQISKIMNIKKDYPDID
                     ISILDKQFINKKKGDCFGGINSYAIDTRGDVYPCTVCVGDKDILLGNIYDGLDDKKIK
                     NLIKIYISKNEECDGCTRLDYCMSTRCKLINKKVTGKFQSAVPIYCGLERVYVETTKK
                     LCSL"
     gene            complement(44368..45666)
                     /locus_tag="KRM55_001017"
     CDS             complement(44368..45666)
                     /locus_tag="KRM55_001017"
                     /inference="COORDINATES: protein
                     motif:HMM:NF015983.1,HMM:TIGR04085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1593274.1"
                     /translation="MIDSEEMIFNVEDLIIYRKNQLVIIYNKKFRKYIKLSEEIYKYF
                     LLGQENKIKIYDFVNYFDDESDKKYIINLIDIMNKNQIFKSNNLNFDMLSNGVAIYFC
                     LTNRCNLFCKHCCVESSSNKKDLLSTYDLKNIVDIISVLNTPHIIITGGEPLIREDFF
                     EIIKYIKQKLPDTKLILSTNGTLIDEHNVDFIITNFEKIDISIDGVDENTCSETRGKG
                     VFNKVISSVNLLKDNGFSNIKLSMVFGQKNSHLNKQFKDLNKKLGTEFVERYFIPTGR
                     GLENKESYLIEDTVLPITIPYILDNELKMCKDKKNKKMGCCACNAGNSQIFINYDGDV
                     YPCPSLIKDDYKMGNIFDNEFVKVIKENKTRDLKSLIKLESIYPYNFEKCKDCDVNIF
                     CWHCPAILDSVKDNELELDRWCSMMKHNLNTAVWGDEKVN"
     gene            complement(46132..47451)
                     /locus_tag="KRM55_001018"
     CDS             complement(46132..47451)
                     /locus_tag="KRM55_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1593275.1"
                     /translation="MLNINVFWIFLPIFSTTIEWIVLKFLLNEFSELRKNRLTLNSSI
                     VIAIMIITMLNTIEFNINIKLFICIFITYVLYKINYVVDKWKSVFISLLYWMLLIGFD
                     SIGLSIVMTLNSIKNMNDLLEDNLLKLELIMISKSLLIVLIPLLKFIRLKTKINKRDC
                     IYLSIPLIANIIGVIVIFEFIFKDKIIDSKESLIILTISTVFLLSNLSLVSIIGRIIK
                     DNSLKIEYEITKKRMNMQYKYYLNLQEYQLKIRKLYHDMNNHIICIQNVYGKNEFADK
                     YIKDINKQIKECNTIFNTQNMILDVILSDKKSICDMNNIYFLVDINFLECNFIEMPDI
                     CSIFSNIIDNAIEACIKIKDTSIQKKIKLRGTVINRLFVIKCENTKINEVVLKNNKVI
                     TSKKDSFLHGIGISSVKSSVEKYNGNVEIYSDKNKFTITIYIPLTRN"
     gene            complement(47445..47573)
                     /locus_tag="KRM55_001019"
     CDS             complement(47445..47573)
                     /locus_tag="KRM55_001019"
                     /inference="COORDINATES: protein motif:HMM:NF016296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593276.1"
                     /translation="MEYIQFICKNTVVINGKDIPVSKYRMANLKKKLTYVLGDVLC"
     gene            complement(47712..48422)
                     /locus_tag="KRM55_001020"
     CDS             complement(47712..48422)
                     /locus_tag="KRM55_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593277.1"
                     /translation="MYRIVICEDDITQIAFLRECILKSLEGISSQIELFEFNSGEELL
                     ETNLEGIDIFFLDIKMLQLTGMDVAKIIRETNDTSEIIFITSIVDYIQEGYKVRAYRY
                     LLKPIDFGDLNESILSCISDIIKKRENFMLIENKGIINKILINSIMYIEVRKKVLTIH
                     TKNDTYYTKNSMDKIELELEKYNFFRCHKSYLINLEYIQFICKNTVVINDEDVPVSKY
                     RMADLKKKLTYVLGDVLC"
     gene            complement(49513..>49699)
                     /locus_tag="KRM55_001021"
     CDS             complement(49513..>49699)
                     /locus_tag="KRM55_001021"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593278.1"
                     /translation="KDGTIVPPDTETKVTLVFTVTHTSSGKTADTGEIEVTVPARTTT
                     VSSLLGRIAVNIFNFNK"
BASE COUNT        16905 a         8103 c         5311 g        19380 t
ORIGIN      
        1 atttataaaa aattaatctt tttgttttaa aatattaata tgtcttatca aacagtttga
       61 aatttcacca agaggtaatt gtaacataac agaacctcta tcaaaagcta ccattggcat
      121 tccatatact atacaagaat tttcatcctg tccaattgta aatgaaccat tttctttcat
      181 ttttaaaagt ccacttgctc catcataacc catacctgta agtattattc ctattgaatt
      241 tttacctgct acttctgcta ctgaatcaaa caaaacgtct actgatggac agtgaccact
      301 tattctttct cctttttcac aagttacata atatccttgt ttatccgtac acaatttcat
      361 ctggtaaccc ccaggtgcaa ttaacacatt tccttgttct actctatcat tattcttagc
      421 ttctcttaca ttcataatac actgtttgtc aagccgttgt gcatacatat aagtaaacat
      481 agctggcata tgttgaacta caacaatccc tggtgttgat tttggtaggt cttttataat
      541 ttcaagtatt gcctctgtac cacctacaga tgcgcctata gcaataacca tattattaaa
      601 acgttccaca ttaccgcctc caaaaaatca tatatcaaaa ataccttttt atcgtttata
      661 tatagcaggt tttacatatt tgtatttagt actacttctg ttgattactt ctgcatgtcc
      721 tacaaacaaa aaactatctt ttttggtagc attataaaat ttatttataa gttcttctct
      781 tgtttttaaa tcaaaataaa tcataacatt tctacaaaaa atcaaatcaa aatgttgata
      841 tgagaaatca ttcattaaat taaacggctt aaaaattaca ctttttctaa tcttatcaca
      901 aattttaaat gtaccatcct tgttgtctat aaaatacttc ttcttccata actcaggaac
      961 attgttaaca tttgattcta tgtatatacc tcttttagct ttttcaagtg agttagttga
     1021 aatatctgtg gctatgattt taatgttcca caactcttta ttatatccaa aataatcatc
     1081 caaagtcata gctattgaat acgcttcttc tccactagaa catcctgcac tccatatatt
     1141 tatgtttctt attttattat tttcttccca aaaaggaagt atactattct gtataaactc
     1201 aaaatgttga ggttctctca taaaaaatgt gtggttagta ctcaatctat ttattaggtt
     1261 tatagcttca tttcctgtct tatctttaaa taatagattc atatattgac taaaagaact
     1321 aagttttttc tctatcattg tattgtataa gcgaccttca attaacgctc tttttttact
     1381 taaatcaata ccatattctt tttttacatg gtttacaaga actataaatt cttcatctgt
     1441 gagttttatc atgcaaaaac ttcctcctgc taatttatca gaactaacta tatgctatta
     1501 atcaaaaact ttcgaatatc taaaattaat atagaattat cttcaacttt cgcaatctct
     1561 tttatatctt tattaatatt agtgttgtta gaattagtcg tctctagtaa atttagattt
     1621 tctatatgaa taacatcaac aactttatct acaataattc caacttgata ctcatcaacc
     1681 tttgtaatta ttatacaagt tctctcatta taatcagctt taggaagatt gtactttata
     1741 tgcatattaa taactggtat tattcttcct ctcaaattaa taactccact tatatatgtt
     1801 ggaagacatg gtacatacgt tattgattga aatcttatgg tttcaatcac attttctaat
     1861 tctattccat aaataacatc attgacataa aatgttaata cttgtttaat aatttcatct
     1921 ttagccatac tttaaatccc ctaatatatt tctataatgc tatctgcatc tataattaaa
     1981 cttatacttc catccccaag tattgtacat cccgataaac ccttattttt tatattaaat
     2041 cggttaaaat aaactggaaa tggtttcaca acaacttgct gattacctat tatttcatca
     2101 acaaaaatac atactgcttt atgctcattt tcaataatta tcatattccc attcatcaga
     2161 ttggttactt ttgtttgaat attatatatt ttatgtaacc ttataatggg aatacatgct
     2221 ccatatattg taattaactc tgtcttattt ccttctgtaa ttatttgatt taagtctgta
     2281 agtttaaatg ttcttcttat ggatgatatt ggtaaagtaa atagtgaatc tccaacttta
     2341 aacttcatac cctctactat agaaagagtt aatggtattt ttatagtaaa ggttgtccct
     2401 tcatcctgtt tactttttac ttcaattgaa cctccaactt tttcaatact tttacgaaca
     2461 atgtccatac ctactcctct tccagaaaat tcagttatag attcttttgt agaaaaacct
     2521 ggagtcataa tcaaagaatt gacctcgtca tcagtatact cattactttg atgtttaaga
     2581 agaccttgtt ccttagcttt tgccaaaatc ttatctctca taatgcctct accatcatct
     2641 gaaatactta tcacagcttc tccgcctaga ttttcagcag ataaaactat ctttcccact
     2701 tcttctttac ctttcgctat acgctcctca ataggctcta ttgcatggtc catagcattt
     2761 cttataaggt gcataaaagg ttctgctaaa ttatcaatta cactcttatc tacctctgtc
     2821 tctgctccta tagttattaa ctctacattt ttatctaatt ttttattcat atctcgtaca
     2881 attctatgca ttttttgaaa tacaccagca atttgaatca tacgcataga cattactata
     2941 tcttgcaatt catctgtaag cttgtgtaat tgtcttgttg ccttattgaa attatctata
     3001 tcaacacctg tagaatttac gctatttaca accattgatt ccataattac aatttctcca
     3061 actatatttt gaagtaagtc caatttttct aaatttacac tcataatact ctgcttactt
     3121 attggtaaat gttcattttc ttcacttaga ctatcttttt ccatatcagt tttttcattt
     3181 aaaacatctt cttgtatctc atcttctgta tagttatttt gataactttt acttacttta
     3241 ttattatctt ttaatttatt ttctactgca tcattgtttg atgtactttt catttctatt
     3301 tcttttttac taatatttat gtattctttt acatagagat tatcttctat agttttataa
     3361 actattgcct tatcctcttt agctacaaat tgtatataaa acccataact tttaatatac
     3421 tctgtagact ctgcatttgt ttctacatct tttggataaa aatctataaa ttcacagtaa
     3481 tctctaagtt caaatacaag catgaaagct ctcacatttt ccatcatgca accttgttca
     3541 aagattattt ttactacatc agagtcttct ttgtattcaa aatttgaatc gattacttct
     3601 ttttcgtctt tactttctaa atttgcatta tcctttgatt tcatagaact tgataattcc
     3661 aaagtactca catactcttc aattccttca ataaaattag agtaatcaga agatatacaa
     3721 cctcttgatt gtaactcatc tatatctctt cttataaaat ctaatgattg aaagactaaa
     3781 tcaaataata ggtcattgtc taaaacttct attttacctt cacgtatagc ataaaacaag
     3841 tcttctacac tatgtgctaa agcagatata ttgtctaacc ccatcataga tgctgaacct
     3901 tttatcgtat gcattattct aaaagtttca ttaatgttgt tatgagtaaa tactttctct
     3961 ttttctattt gaatcataat ttcatctaat tgttcgagta ataaacttgt ctcaaatata
     4021 aacatatcta acatttgtct catactcggt tcaatataat tcacatttat cacctacgac
     4081 ctacaaataa ttttctatta tatatgcatc tcataattta aatccttgat gattctctta
     4141 tctcactata tgtacctcat aatttaaata cacaattatt ctcttacttc aatatatata
     4201 catctcataa tttaaatcct tgattattct cttatttcaa tatatataca tctcataatt
     4261 taaatacatg ataattctct tacttcaata ttcacctcat aatttaaacc catgatgatt
     4321 ctcttacttc actttccttt agatgaaatt tttctactaa ttcttttaaa atttgagcct
     4381 gagcagacat ctcttctgag gctgctgcac tttcctctgc tgttgctgag ttcatttgga
     4441 ctactatgga aatttgctct attccagata aaatctgtgt aattgctact tcttgactat
     4501 gtacagccga agaaatacca ttaatataat tagtagtttt ttctacacca tttactacca
     4561 agtccaatgc atttgcagtc tctttagcaa ttctgacacc attttctact gttttaatag
     4621 cttcttctat gagaatagct gtattttgag ctgcttttgc acttttacca gccaaagacc
     4681 taacttcatc tgctacaact gcaaatcctc taccatattg acctgctctt gctgcttcaa
     4741 cagctgcatt taatgcaaga atattagttt ggaatgctat ctcatctatt gttttgatta
     4801 tttttgatat ttcactcgat ttttcactta tttcacccat tgatgtcatc atatcatcca
     4861 tacatctact tccaaaacca acttgtgatg cagattggtc agatacctca catgcaagac
     4921 tagcactatc tgcacacttc ttaattccat ctgatatctc attaatcgtg gaagctaatt
     4981 cttctactga actagcttgt tcagtagcac cctgtgaaag agcttgtgca cctgctgcaa
     5041 cttgttctga agcacttgca acttgctctg ctgataaatt tatttcagaa aaatcaccat
     5101 taaaagagtt tattatactt tctaaagata ttttaattga tttaaaatca cctataaatt
     5161 cttggtctat ctctactctt aaatctcctt ttgcaatact agttaatgta ctgtctataa
     5221 ggtctatgta atttaaaagc atactttgca tctttttgac agaactcact aatagcccta
     5281 tttcagattt actttcttca acgtctatac ttgttcttaa gtccccagat gcaattcttg
     5341 aaaagtgttt ttctacttta ttaataggaa tcactatttt taattttatt actgtatatt
     5401 ctattattgt caatattatt aaaagggaaa gtataaatat tgttcttaat attagacttt
     5461 gtaattcttt ttttacttct acaattttgg aatttgaacg ggtaactata tcctcttgaa
     5521 attcatttat taaagaatcc attttctctt gggagtttat atagtcacta ccaaaaatta
     5581 tactttgagc tttactctta tcattacttt cgactgcctt tattgcactt tgttctgttg
     5641 gtactaaaga atctgatatt tcttttgctt ctaagatttt atttgactcg ctctttgtaa
     5701 gaccaatttt ttctaatttg tttaaagctg attctcttgt ttttccgtat aattcttttt
     5761 cataaatatc tttattcttt ttttctcctg taaatacata tcttcttaat acatcactta
     5821 tctctctagt tgtatctttt atatactgac tttgagtcct caaattattc atatcattaa
     5881 tacttttttc tactttttca aatgctttat aagatgaaat agaagaaaaa atccctgcta
     5941 gaacagccaa tactataata atcagcaata caattgctaa tttagaaagc tttacttctc
     6001 ttttcatatc tgtactcctt cataaagtaa gtttatatct tttttaatcc tttcattgta
     6061 ctcactacgc tacaatcttt tcctaagttt ttaccctcat acattgcttt atctgctaag
     6121 gatatgtttt cttctaatga tatatttgag tttacttcta ctactcctaa tgtaatagtg
     6181 cactttattt tatgttcttt atagttgaaa tcaaactcct ttatctcttt acggattctt
     6241 tctgaaagta tcttagcacc ttctattgga gtatttgtga gcattatcaa aaactcttct
     6301 ccaccccatc ttgatacagt atcaatttgt ctacaattct tttttattat acttgatatt
     6361 actgttaaca cgaaatcccc tgcttcatgc ccataagtat cattgataac cttaaagtca
     6421 tcaatatcac caaggataag ggatattgat gtttcactat atttattaat tcttctttgc
     6481 tccataagct gattaattat atgtcgccta ttgtaaagac ctgtaagata atctcttaca
     6541 acgagtctat tcaatttttc aagagaagat tccagttcat tatttatctt ttttaattta
     6601 tcttgagatt tctttacttc aagatgagct ataacacgag cttttaattc tgtcatacta
     6661 aaaggtttca ccatatagtc aattgctcct acaccaaatc cttttactat gtctgtatct
     6721 gtattttttg aagttataaa aattataggt atatctgctg tacgagcatt agattttact
     6781 tccttacaaa actcaaaacc agagttatct ggtaaaatta tatcaagcaa aataatgtct
     6841 ggtataaatt cttcaataaa ttcttttgcc tctattgcat taaatgcttt tttaacctta
     6901 aaattatctt ttgtaagtgt tttatctatt aagtcacaca tcagaacact atcatcaacg
     6961 actaaaattg ttccctgttg cttatttttc atatacaaac ctctcttaaa cataatatat
     7021 tcaaatttta atgatttaaa atttttatac ttaataatta taccactata ttcttaaatg
     7081 ttctcatcac aatcttttta taataacact ccaactacat ccctatatta catgatagtg
     7141 caatcaaacc cattgattaa ttcatctatt aaaacttcat ctttatctgt caaaagtttc
     7201 tctaaatcta gtaaagtaat tattttacct tctaattctc caactccact tacaaaataa
     7261 tccgaatatt ctatagtaac tcttggtgga ggtgatattt tgcttttttc taagcttact
     7321 atatcatcaa ctctatcaac cacaaatcca actaccaagt cctttatttc agttactact
     7381 atatacatgc aatttgtagt cattaattca tcttttttaa gtctcaaacg catatctatt
     7441 atcggaatga tttttcctct tagatttatt atgcctttag aatatgtagg tagttctgga
     7501 ataaatataa tttcttgatt tccagtaatt tctattacct tttcaagttc aaccccaaaa
     7561 tcttgctcat ctactctaaa ctttagatac ttaattcctt catcaattag tccataatct
     7621 aaatatgggt catctggaaa tctcatttaa tacctccctc ctaaaataca ctttctatga
     7681 aatatatatt ataatttctt cttaccttta tttattgaat ctacaagtaa ttcacccgtc
     7741 tcagtgtaaa aacgtattgt tctaccataa ttcatacctg tgtcctcagc taatattgga
     7801 atatttaatc ctaaaagagt tttttttact gcctcaacat tcctatgtcc tatacttgca
     7861 attactgaat tgctacttcc taaaaacatc tgagcacctc cagcaatttt tgcttttata
     7921 tatattctat ttgcacctat attctccata gatttaatga gctcatttat tcctgtgtca
     7981 gcaaatttac acttattttc aatgttaata gcatctttac tatatggcaa cataacgtgt
     8041 aacattccac caattccagc tactttatct atcaaacata ctcctacaca agaaccaagt
     8101 gcataagtaa ctaaaacatt tggtctatag gctatcttca tatctgcaat gttcactact
     8161 atctctctat tcatacttct aatcccaacc tcacgagtat ttctctaagt gagctcattt
     8221 ctggaatcat caaaatgtga ctagtaaaat aattatcact cattttaaat ttattttcta
     8281 taaataagac tttgtcacca acatctgaaa atcttatcat aggtacattt agaacagctc
     8341 caaccatatc aatacatata tctggaattg aaacacttat agtcatgttt aacatagatg
     8401 caatagcatt tacatatgaa cttgccataa tatttcctat ttccttaatt gctgaaattt
     8461 caattgcctc aatctcatct aaaaaagctt cttctttatt aaaaagagaa cttagcataa
     8521 gttgagttat tgattcatcc aacaaaaaca taaacattcc attgatatca cctttcatat
     8581 cgagtaaaat acatactact ttgttttctg gaccaccaag caaatttgtc gcttcattat
     8641 attcaagtat cttgaccata ggtattaata cttctacatt gctatttatc atggatgcaa
     8701 gtgcagtaat tgcattccca gagcctatat taccaatttc tctaagagca tctatatgaa
     8761 catcatcaag ttctaaataa tttataatat aaacccctcc ctttattatt gcatttattt
     8821 gcttttcatt gtatcagtgt atatttacac ttttatttta aagcattatc tacaacttta
     8881 actaatgttt ctgttttgaa gggcttcact ataaaatcta acgctccaag ttttatggct
     8941 tctacaatca tattctcttg tcctattgca gagcacatta caaccttagc acttgaatcc
     9001 aactttttta tttctcttag cacctctaaa ccatcttttt ttggcattgt aatatcaagc
     9061 aacatcaaat caggcttttc atatttaaat atattacacg cttcttctcc atcatttgct
     9121 tctattaaat tattatagcc acttttactc agagcttctt taattatcat tctcataaaa
     9181 atagcatcat ctactatcaa aattttattt tccataaaac taactcctcc atatgtacaa
     9241 caataaacgc ttttatcttc agttattgtc tatactatct gactattttt cgctacacaa
     9301 taaatacatt tcattgataa ataaaagtaa ttatttatgc catattatac ttaattctct
     9361 taacataatt tgtcaacaaa aaaacttata tatctattgt aatatatgtt tggcgttttg
     9421 acgagttatt aaaaatataa ttgtataaaa cataaaaagt tatcaaaagt aattaaatta
     9481 taataaaaca actttatacc ttttttatgt ttgtataaaa aaaattttca gattcattaa
     9541 aatcatttct gtagattcat ataggatttg actttctcaa tatctaatag atagttgttt
     9601 atttacttaa ttatatttct ctatatgtat tatcgattaa attagattta gctttataca
     9661 ttatttttta tatttttcaa attgtatacc cataaatcca gaagtattct aatgtgttta
     9721 taatactttt tttcatattt taaactaaat aacaaatcat tatatttaca agtatcattt
     9781 atcaataaac aatattaaat gaagaatatg tctgaagatt caaagtgata ctgatactat
     9841 taattactaa aaaagcagta aatcttttac agatttactg cttatagtta taaataataa
     9901 aactatctat aataaatgta ctatactcaa tacttcattc aatatagtaa taacaaatct
     9961 actttattcc tatataaata tgaacttctt gtttctttgt atcaaaagta ttacattgat
    10021 actcttcaaa atcacttata taagtcctat caaaatccat ttgccaaaac tcaaaccaaa
    10081 aatctcctac ttctttttga cctcctacta taacaaactt tgcatactta cctgctggta
    10141 taactttact aataatactt tctccaacag tattattagt gtttaattct tctaaattct
    10201 tctctttatc agaattacta tttacttcac aacatgcaac aaagctatac ggacttgtaa
    10261 aatcaccctg gtaatctgta tatagaccta ttgtcttgtc attcttttta ccctttatag
    10321 cattatatat ccctttgccc ataaattttt tccacaattc acctatatca tttaccgctt
    10381 gtccatcttt atttgtagtc tccttcgata ttcctataac tattttctca tttatctcta
    10441 ctatttcata attcatactt tatacctcac tttgttttta ttaatctatt ttattttgaa
    10501 ctaattcaat tataatttat aatatacgac acctttatgt catattttta atataattaa
    10561 actcagtgag atattatata ctaaatgcaa gatattatat atttaataaa atctttaatc
    10621 tagcattata ttataatgaa taaattttag acaactccct tagtctagtt attacattat
    10681 ccctaacatc tttaggttca agtacttcaa cattgtcacc aaacgataaa atatatccat
    10741 aaatccattc accaatagga aattctgtaa ttacatcata tgtatcatct tcatttttag
    10801 ttattaaatc cttattaaaa tcatcaaata ctctaaaaag catcttttct ttaaacctca
    10861 atttcaacgt tatagtattt tccttaatta ctttagaatc attcaagcat acttcttcta
    10921 ttatctttct tgaaaacact tcatccttta tagataaatt ccttatccta ctaattctaa
    10981 atatcctaaa atcatctttt agtttacaaa atccatacaa gtaccaagtc ttactcttat
    11041 acataagctt cagtggttcg acagttctgt ttgtctggct tgacaaacta tttacataat
    11101 taaaatttat agtattacgc cttaaaatag cttcttttat ttttgtaaat ttatcatctt
    11161 cattaaaatt acttccccat tcagtaaagt ctatttcaat ccagtttgaa aaattctgct
    11221 ctccaaatat tgagccaatt ttatttacta ctgaatttat ttctggatac ttagtcgcct
    11281 gtaatgtttt cagtgccact attaaactct ctttatcttt ttttgacaat atggccttgt
    11341 ctatagaata ttcttctatt aaagatatcc ctcctccttt gcctttcgtc atatatactg
    11401 gtactcccga catagacaga gtttctatat ctctatatat ggttcttgta gaaacttcaa
    11461 acctatctgc caactcttta gctgttacta attttttatt taatagaatt actattattt
    11521 ctgttaatct atttattttc attcattacc acctactaaa attattaaat ttatttaatc
    11581 taaattaatc atactaattt ttaaataaat aaaatcttag aatcttatct aaattattct
    11641 tacatgattt tatttacttt ctattatctt tctcactttg gatattatca tcttaattta
    11701 tttattacta tatcaattta cttattatca tctcatttgt tatcgtctta cttaatttac
    11761 ttattgctat atcaattcca cttattatca tctgatttaa cttacttatt gctatatcaa
    11821 ttcacttatt atctcatttg ttatcatctt acttaactta cttatttcta tatcaattca
    11881 cttattatcg tcttactcaa tttacttatt gctatgtcaa ttcacttatt atcatctcat
    11941 ttgttatcat cttacttaat ttacttattt ctatatcaat tcacttatta tcatcttaat
    12001 tcatttgctt attatcattt actttattca atttctatat caaaattagt atttgtactt
    12061 aatacttaaa attaatttaa agtctttaca tattatttat tttctattgt aatattcatt
    12121 tccatacttt actaagctac ttccactcat ttattttaaa atttcaattt actatttctc
    12181 aactctatat tattattttt caattttata ttactaattt taaagctttt tagctattat
    12241 tcctacaata tttaaacaaa tttttcataa taaagctata ttacaatata ttcaaaatat
    12301 gtaatatttt agatattttt cgttgacaat gttaaatttt tgttttatcc ttaattaagg
    12361 acatgttatt gacatttctg aaacttattt gaaatagttt tttcatttta tttaggaaaa
    12421 cgtattatac ttaagaaaac gtattttctc atttcagata agtaaaatat ttattctttt
    12481 gaggaggaaa tcatggaaat taataaaaaa cattttattc aagtattttt aacttgctta
    12541 atcttggtag taatatgtga atttataggg caaagaacta tagctattgg aaaagcctct
    12601 atagtactgt tccctatgct ttatgcagtt ataattggac ttataataac accagattta
    12661 ttaggtaaaa aaattaaagc acttaaaaaa gtggttggag aaaaagaaat aaatattgct
    12721 ggtgaagttg ttggaattgc actagtaatg cttggtataa aatatggtac tacagttgga
    12781 ccaaacattg acaaaataat tcaagctgga ccagcgttta tcgctcaaga atttggtcat
    12841 atacttgcac caatcgttgc attacctctt gcattaatgt ttggaatgaa aagagaagct
    12901 gttggagcta ctgcaagtat aagtcgtgaa ccttctttag gagttatatc agaaaaatat
    12961 gggataaact caccagaagg tagtggtgta cttggtacat atttaatggg aacagttctt
    13021 ggtactatat actttagtgt actaggttca atatctattt atagtggtct tcacccatat
    13081 gctttgggaa tggcctgtgg tgttggtagt ggaagtatga tgacagcagc tgctggttca
    13141 ttatctacca tggtaccacc tgaaatggca gatacaatac ttgcctatgc tgcaacaagc
    13201 aatatgatgt ctagtataac aggaattata ttcttagttt ttgtatcctt accatttact
    13261 aattttatgt ataagatttt agaaccaaaa ttttcgagaa ataaaaaaac taaagaaatt
    13321 aaatctacag aaggagagtg ctaataaatg tttgctaatt taaatttaaa gaaaagttca
    13381 tatcaattat tggttatgtc tgttattgga gttataattc ttataggaca aagaattagc
    13441 gttggtacat ctatagttac agctcttcct ggtatggtga tgctaatatt agctgctatg
    13501 gcagctatga ttataaaaga tttatttcct aaatcaatct ttccagcttt tggatttgca
    13561 actataatcg gccttttact tagtatgcca tatagtccaa catctgaagt attcttaact
    13621 aacactaata atattaactt tatggctata actactccac tactagcttt tgcaggaatt
    13681 tctgttggaa acaaaataga agctttaaaa gaaatgtcat ggaaaatagt tataatttca
    13741 cttattgtat ttacaactat attctttgca tgtgcgagta tagctcatat agttttaagt
    13801 attcaaggta aaatatagga ggaatttatt atgaataaag aacaattaaa atctctagta
    13861 ataaaaacta tagatgaaaa tagagaaaaa atattaaaaa taggtcaagg aatatacaaa
    13921 aatccagaat atggatataa agaatttaaa actacagaag ctgtttcaaa cttttttgaa
    13981 caagaattaa atttatctgt agaaaaaaat atagcagtta caggatgcaa agcagatgca
    14041 aattctagca agaaaggtcc tcatatatct atacttggag aattggatgg tatatcatgt
    14101 aaagaacata aagatgctaa tgaaataggt gcttctcata cttgtggaca taatattcaa
    14161 atagctggaa tgttaggtgc tgctgttggt ttagtaaaaa gtggcgtttt agaacattta
    14221 gatggtaaag tatcttttat ggctactcct gctgaagagt ttattgagtt ggaatacaga
    14281 gagcaattaa aaaaagaagg aaaaataact tattttggtg gaaaacaaga attaataaaa
    14341 agaggttatt ttgatgatat agacatatct atgatgtttc atgcttctga tttaggagaa
    14401 gataaggctc tagttggtcc tgagagtaat ggatttgttg gaaaaaaggt taaatttata
    14461 ggtaaagaat ctcatgctgg ttctgctcca catgatggaa taaatgcttt aaatgcagca
    14521 atgcttgcta taaacaacgt gaatgcactt agagaaactt ttaaagagtc tgaaagagtt
    14581 agattccacc ctatcatcac aaaaggtgga gatatagtaa atgttgttcc tgctgatgtt
    14641 catatggaat catatgttag agctagaact ataaatggta tgattgatgc taatgaaaga
    14701 ataaataagg ctttgatggc tggtggaatg gcagttggag ctgatgttga gataactgaa
    14761 attcctggat atcttccaat attacgatac aaaagtcttg ataatttatt taaaaacaat
    14821 cttgaagatt taggtctaaa aggaaaagtt attgatggtg gagattttac aggctctttt
    14881 gattttggag atgtgtctca tataatgcct actcttcacc ctatgattgg tggtgtaaaa
    14941 ggagctcttc atacaagaga ttttgaaata gttgatgaag atttagctta cataattcct
    15001 gctaaagcaa tggcacttac agttgtagac cttctttttg ataatgctaa ggatgctaaa
    15061 gatatattag atacctttac tccagttatg actaaagaag aatatctaac attcttagaa
    15121 aaacacgata aaactttata agtctatttt tataataggg tggtatctac tgtaaaagtt
    15181 ataccactct ttgtttttgt aacagtatac ttcttttctt ttagttttta gattaaacta
    15241 agatatatta tcctccttaa aacttttaga gctacgttga aatatcagta gaactatgct
    15301 atattctttc taattaatat aaatttctat tctaattcaa ggtggtgaaa aaatgtttaa
    15361 tgcaggaaat cgaattataa atacatggtt gtaccctatt caagatggct ttgtcttgat
    15421 tgatactgga tatgaaaatg gttttaaaca tttcaaaaaa cgaatttcta aattcaacat
    15481 aaaaatcaaa gatattcgat acatatttct aactcatgct catgatgacc atgttggttt
    15541 tctaaatcag attctagacg aatctcctaa tacaaagatt gttatgcatg ataaagcttt
    15601 agaaattcta tataaaggtc aaaactcttt tattggtggt tgtaccagcc gtactgcctt
    15661 tctcttttgc caaattatga aactatttgg aaaaggtgag catagttttt ctccacttaa
    15721 acaagaattt gaaaaaaggt gtattcttgt gtctgacaag aatcgtaaag aaattgaaaa
    15781 agaactaaat ggaaaaatta tagatacacc aggacatact gctgattcaa tttcactact
    15841 aattgatgat ggtgttttat tttgtggaga ttctgcaatg aatggatttc caagtactca
    15901 caaaattacc atatttgcag aaaacaaact agaatttatt caatcttgga aaacaatcat
    15961 caatacaaaa cctaaaatga tttatcctgg acatggaaaa ccatttgaat acagtaaatt
    16021 agaacaaaat ctaatctatg taaataaaat aaatttatat cctctacata attcaaaaga
    16081 tattcacaga tttttgtaga aaatacaaag taaatttatt tgattaatta aaaaatctaa
    16141 cactttacta cgctacttat tttaataact taatcttcca ctagcttttc ataaaatttt
    16201 gttttaaaat taattttaaa gtgcatatgt tatttaaata cattagataa aattcgtcat
    16261 taatctactt aaagcatatt taactaacac cactcaacca gaaaattcag aaaactgcat
    16321 tgacacagga aaaagtttat tttatacttt ttttaggaca tattgtggac acgtcttaaa
    16381 tcgacaaaca gaatttaaat tgtaagatta accacaatac ttatttttta attatatttt
    16441 taaacattag ggaggatatt atgaatgata acgtagttaa gaagaaaaac ttttttgaca
    16501 ggacattaaa cagaatagaa actgttggta ataaactacc agacccagtt acaatatttt
    16561 tagggttatg tgtactttta cttatactat ctagtctagt tggttctatg ggtatatcag
    16621 tagttcatcc tggtactgga gaaactataa ccgctgtaaa tttattgact gtagaacagc
    16681 ttcaaattct tttaggaaac atagtcagca atttccaagg gtttgctcct ttgggtctag
    16741 ttctagtaac tatgataggt gctggtgtat gtgacaaaac aggacttatg acagcaacaa
    16801 tcaaagcatc agtaagcaag attcctgaaa caagagtaac tcttgttgta atgactatag
    16861 gtatgcttgc caatatagct tcagatgcag gtacaatatt atttccacca ttagctgcac
    16921 ttgtatatct tggtgttggt agacatccac ttataggttt attttctgga tatgcagcag
    16981 tctgtctagg atttgccgca aacattatga taagtgtcaa tgatatactt gctgcaagtt
    17041 ttacagttcc agcagctcaa atgattgatt ctggatttca agccaatgca acaatgaact
    17101 tattttttat gatagcatca acttttgttc taatactttt ggcaacatgg gtaacagaaa
    17161 aaattgtagc tcctagattt ggtaaatatg aaggaaatgc agaactagat gttgatggaa
    17221 gtcttagtga tgtagaaaag aaagggctta aaaaagctgg tataagtata ttaatatatg
    17281 tggctattat agtagctctt agtgtaatcg gtaaaaaacc attcttagct gacccagaaa
    17341 caggagattt actatcaaac aatgctcctc ttatgaaagg tatggtacct ataatagcac
    17401 tagcattttt catacctggt gttgtatacg gaaaaactat aggtaaaata aagaaggata
    17461 aggatgtagt ctctataatg gctagtgcaa tgagtgatat gggtggatat ataatactag
    17521 catttgctgc ttcacaattt ttgcaattat tcacaaatag taatttaggt ctgatactag
    17581 ctgtaaaggg cggagaattt ttaaaatcag caggaataaa tggaccttta ttgttgatag
    17641 gatttattat attatcatgt tttataaatt tatttatagg tagtgcatct gcaaagtggg
    17701 ctattcttgc acctatattt gtaccaatgt ttatgatggt tggatacaat ccagcactta
    17761 ctcagatggc ttatcgtata ggtgattgta taacaaatcc acttagccca ttatttccgt
    17821 acttccctat tatactagca ttcacaagaa aatacgataa agatgctggt atgggtactg
    17881 taattgctaa tatgatacca tactctatat cattcttaat agtgtggact atactattaa
    17941 tattgtttat ggtatttaat attccactag gacctggaat acttccttca tatagcatgt
    18001 aatttattta aatctttcta aaaggagaaa taatttatgt tagataaaaa tagacttata
    18061 aataatttta tggatatggt tagaattgat agcccatcta atcaagaatt agaaatgtct
    18121 aagtggttgg taaactactt aaaagaaaga aatatagacg ccattataga tgatgcaggt
    18181 gaaaaatatg gtggtaatac aggtaatgtc attgcctata taaaaggtga agaaggaagt
    18241 agaccacttt gtttatgtgc acacatggac caagttcaac cttgtttagg tgtaaaacca
    18301 atactagatg gtaatgtagt tagaagtgat ggaactacta cacttggtgc agatgataaa
    18361 gctggaatag ctgctatact tgaagcttta gaacatgtta ttacagaaaa aataccacat
    18421 agagatattt atctttgttt tacaatctgt gaggaagctg gtatgcatgg tgtcaaaaac
    18481 tttaatcctg acaacttgcc ttgtaaagat atggtgattt tagattctgg tggagctatt
    18541 ggttcgatag catacaaagc tcctgctcaa caatctataa aaatctcttt tcatggaaag
    18601 aaagcacatg ctggtataga acctgaaaaa gggttaaatg ctatattagt agcctctcat
    18661 gcaataagca acatgcacat aggcagaata gattcattga ctacttcaaa tataggtaaa
    18721 atagaaggtg gtggagctac aaacatagta actgataagg ttacattgac tgctgaaatt
    18781 aggtctcata tacctgaaac tttagagtat gagcttaatc atatggaaaa atgttgtaag
    18841 gacgctgcat ctaaatttaa tactacttat acttttgaac ataatatgtc ttaccctagt
    18901 tttgaactta gtagagatag tcacgttttc aagttaagtg aagaagcaat aagacaagtt
    18961 ggtgttgttc caaatccaat ggtaattggt ggtggaagtg acgcaaatat attagctaat
    19021 cttggatata attgtgctat attaagtcta ggtatgtatg atgtacacac agttaatgaa
    19081 tatgtaaata tagacgaatt atatgatact gccaaaatag tttatcatat gattaaatta
    19141 taaatatcat aatataactc tttaaattat aaaaataaaa acctatgtat cttcaacttt
    19201 ataagttata tattaaagtt gttttacata ggttttagta ttttatataa taatttgttt
    19261 taacattttt cataataagc ttcaatattt tgcataataa tttgttctag catttttaat
    19321 aacaagcttt agtattttat attaataatt tattctagta ttttacataa tcatttgttc
    19381 taattttttt cataataagc tttaatactt tatatagtaa tttgttgtag aattttatac
    19441 aatataatga tttatacagt tttataaaat atcttaaaac agtatttcag taatattttt
    19501 tggtcttcct ccaccaatac tagtctcttt tgcacatatt cgacctaaac ctgcatttac
    19561 tattttattt aatatacgtc ttgcacttct ttcacttaca tttagatact ctgctaactc
    19621 ttttgaatca taaatcttac tttttctatt ctcatttata gcaataattt ttgcaactga
    19681 ctcacaactc atcccagtct ttttagatat ttcgattacc ttttcatcag atagcatcaa
    19741 agaataattt aattcatttt cggaagctaa aggtcctctt atgttttcat cttcatctac
    19801 caaatatata ccaatttctt ttgaatctat ggagtgtctt aatgctttat gtgcattatt
    19861 ttcagcctga tacgcagtta ctccagtgcc aattcctata ctaagagaaa agcccatgtc
    19921 ttttatctct ctctttagat tgaatagctt atcataatta tactcattat cagctacccc
    19981 tttatgaaca aatacaacat aatcatttct tccaagtaaa aataaggaac cttgaatgct
    20041 tcttacatag tttactacaa gcttatccat atctgatttt tttatcatgt cagaataata
    20101 gttatctatc ttctctttat aatctattaa actcaatatt tcaacagcaa tttgagaaaa
    20161 tcttgcctta cttagagcat attcactctt taccttgtca taactttctt tgattaattg
    20221 tatagtagct tgtaaacgaa atacaggata gcctctttct tttaattcat tatatactgc
    20281 accaaaacca gttaacatta tatccgtctt attttcttca aataatttta tatgccattc
    20341 tacaagttca gactctccca cttccaaaga aaatggatta caaaatacac tcgttgcttt
    20401 aatatcaaat tctttaagtg catcttccac aacatatcta tcaactacat ctatactgaa
    20461 tttatctaat tttatatttg cactttttat tgcccaaaat gccttcatta tactcgtccc
    20521 acttctcggt acaaatgaat gtggcttact tatctcatac ttagatttta taaattcata
    20581 aactgcacat cctgtaaata taatagcatc acattcgtct tcacatttag aaataacttc
    20641 tattgtatct actacttttt ctcttacata tattttagtc tttaaatcac tgtctatctg
    20701 ttttaaatca tcctttatct taaacccaga gtctgaagga cctataatac ccactatcat
    20761 aaacttcgct cctaatccat aaatattata ctttttaaaa attatatcct cactattttc
    20821 tacttctatt taattatttt gaactactcc atcctacgtg catttagaat ggaataatta
    20881 gcttattttt gataaagtaa cttctcaaaa tcagcacttg gaataggctt acaataataa
    20941 taaccttgaa ttaccacaca atctaaactc actaaaaatt cagcttgttc ttttgtctct
    21001 acaccttctg ccactacatc catatctaaa tcttttgcca tggctatagt gtgctttaaa
    21061 actatttttt ctctgtctgt gattccttcc tcattaaaga aaccacaatc tatctttaat
    21121 gtatcaatat taatattttt taacatattt aatgaagaat atgctgaacc aaagtcatcc
    21181 atatttaaaa caataccatc cattctaagg tcggctatta tcttagtaaa taattttata
    21241 tttttaataa ataaactttc tgtaagctct aattctaaaa aagattttgg tatactatat
    21301 ttatttatta aacttaaaac aatttcttta aaatgtggat tatgcaaatg taatcttgat
    21361 acatttacag agataggaac tggctcttca cctaaatcta tccattttct aatcaaagaa
    21421 catacttgtt cccatacata catatctaat ctgataataa acccattctt ctcaaatagt
    21481 gaaataaatt taattggagg tattatacct ttttctggat gaacccatct aaccaatgct
    21541 tctgcaccaa caattttatt tgcattaaga ttatacttag gttgtaaata tacatggaat
    21601 tgcccatttt caagtgcgta ttccatttcc ctttccatct gtttttcttc aagtgcatca
    21661 tttcttatag tatcatcata aaatatatag ttattgatac tttgtttctt tacttttttg
    21721 tgagcatatc ctgccatttc acacgcattt gtaattggaa tatgattatc caaaattcta
    21781 taaaccccaa aacatggtac taacatatat tcaaattttt ttctatttaa gctattttta
    21841 atcttataaa ttaccttatg aatatctcta tcagagtaac tctcataaaa aatgcaaaat
    21901 acatctgcat acatacgaca acatatacca ttagaaccaa tgtttttttg aatcaactct
    21961 gcaacatata ttaaagcttt atctcctcct ctaactccat aaatgtcatt aattaccttg
    22021 aacttatcta tatccatcat tataattgca taacgcttgt caggatatct tttaagcatt
    22081 atacttattt gttcacaaaa actttcataa ttgtatagtc ctgttaatgt atctttttgg
    22141 tttttatgta gttgcataag ataatctata ttttttatag caactaaaat atgtgtttgt
    22201 ttctcaccta acttattttt actactaatc tttaacatat aaattaatgc ccaatagtac
    22261 tttttatcta ttcctaaacg tctatactca aaatttagtt ctaaatcgtc ttgcttgcta
    22321 ttattaagac tatcaagaga ttttagaagg tggttatcat taaataatat tatatcatca
    22381 ggatgaatta aatgtttttt tatgtatgaa aaagtttttt caagattttc ctttatagga
    22441 aaactaaaaa tattgctctc tgattgataa attggagtaa ttaaattcgt atcaatgcaa
    22501 atagataaaa ttatatcata tgtattataa gctaattttt cataagcttt agaataccct
    22561 tttatcatta aatcatcaaa ataaacctta tcaactaact ctttatgttt aaataaaata
    22621 ttattcgtcg aatcagctaa gtcactaatt actttcattt cattatttct aagtttgttc
    22681 ttattataat acctcttctt atcttggtac attctctcat cagcaacttt aattagctta
    22741 tgtatatcaa tattatcgtc actccaaata ctgcccactg ctacactata tatcatctca
    22801 tccttaaatt cttcacttaa ccaactcact aattcttcaa atagttgttt tgatatatct
    22861 tcacataata caacaaactc atctcctcca atacggtaaa cattataaga atgaaagtat
    22921 ttttttatta ttacacatgc tgacacaata gcagaatcgc cattagcatg tccaaagtta
    22981 tcattaatat cttttaaccc atttatatct acaaatacaa ctcctatgga tttaactttt
    23041 cctttttgaa aattatctat atacttaata tatttatttc tattatatgc accagtcaag
    23101 aagtcatagt agctcatata atttaattta ttttctactt ttcttttttt catctcagtt
    23161 aataaaaaat aagataggga tgtcaaaaga gaggtatctc caacagcttt atgtggatta
    23221 tcaactccaa taaaccctac tactttatca tcttgtttta gtgaagatgt cattaaactt
    23281 tcaatttttt gaggttttaa aatttcatat tctattggct gttcttcttt tatattttct
    23341 atatcatcaa ttattacaaa acctttttgt tcgaataata aaaaccaatt ctttaattca
    23401 ttaatatcaa gatttgttag tgcctgtttt tgttcatcaa caccttcatt gcaccattca
    23461 tatgtattag ttactttttt tctatcttct gatacttcaa aaacatatgc tctatcagct
    23521 ttatgaaatt taccaatatt ggttaataca agatttacag catcagaaaa attagattct
    23581 gttataagat gtttaataca tccaactaat aactccttta tctctaattt ttctgctatt
    23641 gacttactta tatcttcctt ttctgtaata tcaagagcta tttctaatcg tgcatgtttg
    23701 ccctcccatt taattaactt gtcctttaat ataaaatgtc tatttgttcg agtattcgta
    23761 ttttcccata tgtaatattc atcttctttt aaaatagagt ttgtacaaaa ttcgcaggga
    23821 gaatctttcc cctgtaatgc tttataacat tttaaatggg atatatcatt aagtcccatt
    23881 gcctttttcc caatttcatt aatatataaa agttcatatg tatctaaaga agaaacatat
    23941 acaatttcat ccaactcatc tattaaattt attacatcca tttatatata tctcctttta
    24001 ttcattttcc agattgaatt tttaaagctt ttaaaatttt gctatatatt tggcaatgat
    24061 attatacttc tttatgtttt aaaatagtac cttaatgagg ttctattttt tagtaaatag
    24121 aattattatt gtgtcaatcg tacaatagag ttttgtaata cttaatttaa tatatttata
    24181 attaactatc ttattatgta tttacaatta attctcatat aaatgacaaa tctccacctc
    24241 aattaagtat tccaatcata tatgaggata atacttcatt catttaaaaa tataaaacta
    24301 ttatatatta aaatttcttc aataataaat tatttagatt gttactttga tatattatat
    24361 aatatcacaa aggctgatat aaaaagacaa aaagggcaat ttttttatat caaaaaaaat
    24421 gttaaattga tattatccat atataaattg atattatcca tatagatgct atatttaaca
    24481 attctactta cttcccttac acttattagc atatagttat taagagtttg ttgcaaaaca
    24541 acacttagca cactttaaaa agtgtggtct aataagtaat caacgaagaa gacataataa
    24601 agcataaaat atgatatact tttccacgtc atcaaaattg aggattttat tattaatata
    24661 tgataaaata tgcttaataa attaaatttt aatgggagaa tagttatgaa aatatttagt
    24721 ttcttgttgt ttgtagtggg aatatgtttt tgtattgctg gatttatggg gcattcctca
    24781 gctttttctg gtgcaacatt gagttttttt gcaactacaa tgatagctgt aagacaagtc
    24841 aaaactaaga aaaaatgaaa taggcaaatc ctaactttac aagttaatat tacataagta
    24901 attagtctaa aattggatac tttttctatt acagaaatac atcatccact ttgtattttc
    24961 ttaaaaaaat aaaatagcta tgtaaattca agattagata gattaactct ctatccattt
    25021 cattgtaaaa tatacatagc tatttgtatt cgatttaaaa tacttagatt ttcttacata
    25081 acaaataatt tctatctgat tattactcat attcatttag taatcactca gcaactaatc
    25141 atttagtatc tattcatccg ccatacggta acctacccca acctcagtca aaatatattc
    25201 tggctgagca ggattctttt caattttcct tcttatactt gccataaaaa ctctaagcga
    25261 ctgattttca ctttcatagt aatttcccca aactttatct attataaact tatgggttaa
    25321 gactcttcct gaatacttag acatcaactc aataatctta tattcgattg gagttaaatg
    25381 tatttcttca ccattaattg acacaatatg attttcataa tctatcttta ggtttttaac
    25441 ttcaaaagac tttggagcat cattatttat attatcctgt tgagctttat ttctaagagc
    25501 cacacgtact ctagccaaaa gctctgttac actaaaaggt ttagttaaat aatcgtctgc
    25561 tcctccatct aaagcttcca ccttatccct ctcatgctct ctcgctgaaa caacaattat
    25621 tttattagtc tttgcacatg ccctaactcg tcctattacc tcaatcccat caatatctgg
    25681 taatcctaaa tccaaaatta tcaaatctgg gtcaagagaa tgtataagtg atatagctgt
    25741 tcctccatta tctgtctcta cacacctata attttgagtt tcaagagata cttttataaa
    25801 tttacaaatt ggcttatcat cttctacaat tagaactaat ggctttattt ccacttgtct
    25861 ttcccctcct catcatacat aggtatgcta aatctaaatg tagctcctcc agaaggatta
    25921 ttaaaggcga caatttctcc accatgagct tctactatag atttacatat ctccaatcca
    25981 agaccaatac ctcttctttc aagatttcta gacttattct tagtataaaa cctattaaaa
    26041 atattcccga tatcttcatt tggtattcct tttccattat ctgcaacttc aaatagtact
    26101 tgatttgact ctttttttac agttagttct atcttagaat ttttaggtgt atgccttata
    26161 gcattatcaa ttagatttac taacacttgt tctattaata atacatccac atgaacgatt
    26221 attatctcat ctggaatatt tgtttttatg tctctactat tggcaaactt tttgactctt
    26281 aatatagatt cagctattat ttcatcaaca acctctggtc gtttttcaat atccaatttt
    26341 ccttcatcta ttctggtcat actaagtata ttctcaacag aatgagttag ccaactcgta
    26401 tcttcatata tatttttcaa taattctact ctagtttctt tatctatcac atcatcattt
    26461 tcaagtattg ttgaagatga acctaatata cttgtaagtg gagttcttaa atcatgagaa
    26521 attgacctaa gcaagtttcc tcttaatctc tctctctctg cctcaagatt tgctttttta
    26581 tttttctcaa ataaattttc tctatcaatt gccaacgcaa cctgtgttga aactgcttct
    26641 aatagtatct tttcattttc tgtaataata tctatcttaa aacacgcaac acctataaca
    26701 ccaagaacat ttgattcttg accttttata gggaaataat atgcactgct gtttttacaa
    26761 tattttgtcc caattccaac tgggttacct gtcctaaaag cttcttttat agcttccttt
    26821 tctaatactg aatggaatat attctcactt ccatcattgt tacaaatata aatacttggc
    26881 ttacctagat tattattctc atctgcaata gtcactatta cagttctatt taatatattt
    26941 actaaattag acccacaaaa ttcaataatt tgatttttat tttttgcttt aagcaacgtt
    27001 ttgttattct catagagcaa tcttatcatt ttttctctct tatgagaaag tctcacttct
    27061 ctttttatcc tagaagttaa agtacttgtt ataattgctg ccattagcat aatacaaaag
    27121 gtcataggat aatcttttct ataagctaaa aaagtatata atggatgcgt aaagaaaaaa
    27181 ttaaatgata gcactcctat tactgaagaa agtattccaa aaaaatatcc ataggttata
    27241 cttgtagcaa atagtacacc taatatgtat actagtataa tattagattc attaaaacct
    27301 accttttcaa aaactactga tattccagta gcaattgtca taaccaatat agtttttatg
    27361 aagtccttaa taattatctt tttactgaga tagccatctt catcataatc atactctttt
    27421 aagtcttcat gttgtagtcg ttcctttttc atttactaca attcctcctt attgttactg
    27481 tttaaattgg ctctatttta tataatacaa ttttatcata ataaattcaa tcaatacatt
    27541 taattaatgt acttaaatta ctaaaaggtg ctgtcttaaa atgaaaataa atctctattt
    27601 caaaacagca cctatatatt taaattacta atttagtttt tacatactta aatcaatagt
    27661 tttattcaat ttcataaatt ataatacttc aattataaaa catttctatc caacaagcat
    27721 aaatataaag tgggcacata tacctgcaca taaaccacct atagtatgcg aaagtatcgc
    27781 tttaccagcc aatggtcttg catctaaagc atccatcata cctatgtgtg tacttaaata
    27841 tccactccaa cacataccca ttgctgtgaa tactgctata tcattaggag ttatagcgcc
    27901 tgattttata aactctggta ctaaagatat tgctgctcca acagctccta atgcagttac
    27961 agggaatgct attgcctctg gtgatgtgaa tccaaataat ggttctatta tgaagctaat
    28021 cttatcacca atagcaggta ataattttat accttcatat gcagctcctg tgtaaacagc
    28081 ttgacctgta gcagggtctg tagatggtcc aaaagttaat aacataacta atgtacaaac
    28141 tactaaaact cctggtatta tagccatacc catttcaaca cctaacttac caccttcaag
    28201 tatagcatcc aatgttcttt ggaatacatt accatctctt atttctctaa actcttcaag
    28261 ttttgcacct ttatcattta tttgcttttc agtatcattt ttagggtcat aattataata
    28321 ctttttagta aaagtcaaca taattctaac actaataata ctacctatta ttgccgcaac
    28381 attacctatt atagctggta gtacatattc tttaccttga gctatcataa aagttgttac
    28441 aataagtccc ataccaaagg ctgttcctaa attacataaa gcaggtactt gatacttctt
    28501 aaaatattgt gtaaatgttt tgtctttagc aaatggtata atagctggat tatcagataa
    28561 atatgttgca actactcctg ctatactagc accaggtaag ccccatatag gtctcataag
    28621 acccttaaat atcttattaa ctaaagatat tactccaaac tctgaaagca atgcactaag
    28681 tgcacctgca agaactgcca tagccattat taaaaatact gtgtctaata aaagcgcatg
    28741 tgctgtactc attattactt taaacatcat tcctgcaccc atgatgcttc ctacatatcc
    28801 aaatcctacc gccaatagta caataaatac gaaggtttcc atacttactg ccttgactct
    28861 tctcttatcc gacagctttt ccatcttgaa atcttccccc ttttaatttt aaattaaggt
    28921 tcctaacatt ggtacaaatt ttttggtaca aactgagttc taaaacttac actcgtaatg
    28981 caagttgtca gttttttgaa ataaaaaaaa attacgttta tagaataaga atatcctctt
    29041 taatttggat actcttattc tattttatgt tattatatta tcatcctttt gtttaaaagt
    29101 caattttttc tatttttgtt gtttaatttt atttatactc tttttatatt tttcattttc
    29161 ttttatcttt gtaagtactc catataagtt gacttttcta aatacagtag ttataaatac
    29221 caatcctaat gcaattgaac ttgcacacga taatgtactc accccatatt ctacagcttt
    29281 tatataatta ttggtcaaaa cagaatacat agtattatat attccataac caggtactaa
    29341 tattattaaa cagcaaacac ttaatgtagt tgctggagtc atataaattc ttgcacataa
    29401 ctcacaatat atcgcaaaac aaactgtagc tataaaaaaa cataagtttt ctgttactcc
    29461 catatttaaa agaaatttat acgaaaacca agctatactt ccacctattc ctgctagtat
    29521 taagtttttt cctttcatat taaatagcac tccaaagctt aaggcagtaa aaaaagctgc
    29581 tattacttct ataaacaaat gcacttatat cccccctaac ttgaagtaca atccaagtac
    29641 caagaacatt cctactgcta tagatacacc tacaaaaaat acttctgcta attttgcaag
    29701 accagaaatc aactgtccat ctaacaaatc tcttaatgca ttagtcaaag caagccctgg
    29761 aactaagagc attattgctc ctgctattaa atggtctaac gtctttatga atccgagctt
    29821 taaaattaaa attgaacaag aagctataat aactgctcca attgcattta caaaaaagtc
    29881 attaagggaa gatttactta aatacataat aacaaactta gtcagaatcc caacagtaaa
    29941 tgcagctata aattcttcca catttcctcc aaataatatc gaaaaagttg ctgctgcaat
    30001 acctgcaaaa aatattgtta ttaaatctga gtaatagtta tcttcactta tttcatctaa
    30061 aattttctca cataattcaa tatctaaatt atttatactt attgctcttg ataatgagtt
    30121 aacttcatga accaagttta ggtctactct tcttgagctt attcttttaa ttgctgaatg
    30181 taatttccca tctacaaata cagatgccat tacagctgtt ggagttgcaa atacatctac
    30241 gtggtctatt ccaaaagatt gacatattct agctatcgtt tcttcaactc tataggtttc
    30301 tcctccactt tgcaacatag ctttacctgc atttgaggaa aagtttaaaa ttctatctat
    30361 atccacaaaa catatctccc attcttttat agtattattc atattttaat acaagatatt
    30421 atttatttaa actattttaa ataattcata tccaatattt acattttatg aaaaaacttg
    30481 ttttttatgc ttgtcaaaat caaattttaa gcttgtttac accataaaat ggctgaatta
    30541 atatttgaca aacactttca accatttata taaccttcta aattgtataa ctttttacta
    30601 caaataaaat tatatctctt ttaattcttt ctcttgagta tttagcttat agcaacttca
    30661 tattcatata tgtacaatat aaaacattat ttttatgata caaaatataa tttgtaaatg
    30721 tatatatgta ttaactgtgt atatataaat tattcttaac cttatcagtt ttttcatata
    30781 tcttcatcta tactgaccat atattaatta cattgaccat atattaataa atgatattac
    30841 atagacttaa gtatattaaa aaacttaaat ttagttattt aacaacataa tactctaatt
    30901 taatctataa aaatccatac ctaatataat gcaactctta ttttaacacc atctattaca
    30961 caaaacaaca tattaaaaag taaaatacaa aatatccact ataaacctta ttttaatact
    31021 gaatatatat tataatatat ttaatgtagc ttaaatatag tttaaacata aagaaaggaa
    31081 acggtatatg ctaagaaaag ataaagttct attatctcta cataaattat gtgaaaatat
    31141 gactttaaaa gaccttcaat cagataaaac aggattcact acaatagaaa ttgctaacca
    31201 ttcatctctt gatagaagta ataccagtaa agaattaaat aacctataca atgaaaaaaa
    31261 agttctgaaa atatctggta agccaatttt atttctacat gctagtatta tagaaaattt
    31321 aattggccgt actttgaaca gtgatgaatt ttctataaat aattgtaatg agctacttaa
    31381 atcaagtaaa aatgactcag aagatatttt ttcaacatta cttggacatg attctagtct
    31441 taaactacct atagaaaaag ctaaatctgc tatactctat cctccaaaag gtcttaatac
    31501 attactaata ggacctactg gtgttggaaa aagtacattt gctgaaacaa tgtacaaata
    31561 tgctgtagaa agtaaaatct tttcttctga aagcaaattc gtagtattta actgtgctga
    31621 atatgcagaa aatgctaact tattattaag taatttattt ggttatgtca aaggttcttt
    31681 tactggtgct aataaggata aattcggcat agttgcacag gctgatggag gcatattatt
    31741 cttagatgaa atacacagat taccaccaga aggtcaagag atgctttttc ttttgatgga
    31801 caaaggcata tacagacgat taggagaatc tgacattgtg cataaagcta atgtctttat
    31861 tgtgtgtgcc acaacagaag atatacattc ttctctgctt gggacttttt taagaagaat
    31921 ccctgttaca atcaacctac ctgctttaca ggataggtct ttaaaagaaa gattatctct
    31981 tattaaatac ttctttatta tagaatcaaa atacaccaat gcaactataa aagttcacaa
    32041 agatgtaatt aaatcattac tcctttatga ttgttttggt aatataggtc agcttaaatc
    32101 tgacatacaa cttatgagtg caagagcctt cttaaattac aaaactggac ttaaggataa
    32161 tatagaaata gatctatccc ttgttcctga ttacatctat attggtcttt taaaattgaa
    32221 tgaaaatcgt agtaatctaa ataaattatc agaacttgat tatatgcttt tttatgaatt
    32281 taatggtaat aacttagaag ttgaatatac aaaagaacta tctaaataca atatagatac
    32341 atcaaacaat ggatttaaat actctacaga gattccttat ctggaaaatg atataaggag
    32401 tatgtttata aattacatgg aaaagtactc tacaaaatta ctttcgatat cttcagtaac
    32461 tcattctgat tatacaagta atgagatttt taaagtaatc aatccaaaga tttactatgc
    32521 tgttgaacat tctttaaaag aggctgaaaa aatatcgaga aacaaataca caaaacaaac
    32581 ttatattgct ctttcaatgc atataagtgc acttatagaa aatataaatc aagacacata
    32641 taatcctaag tacaatttat ataatgataa aattttctta gataaagatt taaatatagc
    32701 taaaatagtt ttaagtataa ttgaaaatga cttacaaaca tctttaccta aagatgaagt
    32761 aaaatttata tccatgtttc taaatagcat gtatcttgaa ccaaacaatc aatctgaaag
    32821 tataggagtc ataatacttg ctcatggaaa ttcaacagca agcagtatgt gtgatgtagc
    32881 aaattcattg cttggtacaa accattgtaa tgcaattgac atgcctcttg atgtaaaagt
    32941 aagtaccata cttgataaaa ctatagagtt ggtaaaagaa tgtgacgaag gtaagggtgt
    33001 acttctttta acagatatgg gctctcttat agcttttgga gaacttattt cagaaaaaac
    33061 aaaaatcaaa actcgctcaa ttgaaatggt atctactcca atagttttag aagcagtaag
    33121 aaaaagtaca ctaccagaaa tgactttgga tgaattagct aattccttaa gctctttaaa
    33181 tccatatatt ggacgagcag caatcgattc aacagaaata aactatcctg aaaagtcaag
    33241 agagtatgta ataataacta cttgtataac aggatatggt tcagctatga aagtagcaga
    33301 ctttataaat tcttcactta aaaatattag taaatacaat attaatttag ttcctcataa
    33361 tatagaaagt tttaaaatgt ataagaataa atttagtaat actaaaattc tggcagttgt
    33421 tggaagtgta gattttaatg tagccaacac cccttttata cacatagagg aactactaaa
    33481 tggatatggc ctagatatgc taaacaaaat aatagaaggt acattcaatg ccaatagtat
    33541 tacaaatata aaagaaacaa atctatcata caacagttta ataataaact ttatgaccca
    33601 aaacttagag cttttggact ctgttaaatt attcaactat gtcaattctt ccttatttac
    33661 aataatagaa ttaatagatg aaaacttaaa gagcaaattt aagctaggat atatactaca
    33721 ttgctctttt atgatagaaa gatgttttaa aaatacaact tttccatata ataacattac
    33781 tgaattaatt agtaaaaatc atgaactata tagtttaata cgtgaagcct ttaagccaac
    33841 agaagcttat tttaatattt tgataccaga cgaagaaatt gcttatataa tagacatgat
    33901 taatgagtat ctaaataaat aaaatttata gcacttattt tgtgcatatt aattaatata
    33961 tgaaatggag gacgagattt tgaaaggaaa aataaaacag ttaacaatac ttgcattaat
    34021 ttttatattt ataactcctg tatttgcatt tgcagatact ccaccagtac caaattcttc
    34081 aagagcagca ctacttatag accaggaaac taaaagaata ttatttgaaa aaaacattga
    34141 tgaaaaaatg ccattagcga gtttaagtaa aatgatgacc tttttattgg caatagaagc
    34201 agttgataaa aatcaagtta aagagactga tatggtgaaa atagacaagt ctacagcttc
    34261 agtaggaggt tctacttgta aacttaaaga tggtgatgaa atatctctag gagagcttat
    34321 gcagggtcta atgctagtat ctggaaatga tgctgctata gccatagcta aacatattgg
    34381 taaaactgaa aagaattttg taaatatgat gaacaaaaaa gcagaagaaa taggaatgat
    34441 tgatacgtat tattttaatc caaatgggct tcctatatat actgacccag aacataaaga
    34501 acctcctatt gaaaatatgt caactgctca cgatatagtt acacttggaa agtatatgta
    34561 cgaccattat gaaaatcaag ttacaagaat aaccactatg caagtatata atgatactaa
    34621 aaaggatttt acacattata acacaaatcc tctgcttgtt tcagtacctg gtgttgatgg
    34681 aataaagaca ggatatacag ataatgctgg atattgcctt gcattttcta tgatggtacc
    34741 taaagatgct aaaaacgaaa gaaatcatag attgataggt gttgtacttg gtgatggtaa
    34801 caagaaaaat agaatttctt cttccgctac tttattgaaa tatggtaaag ataatttcca
    34861 ttctaaaaag atagcacata agggtgatat tatagagact ccttgtgttg atggtattga
    34921 tgattttaag ataacagtta aggttgataa agatttgtat ggtgttgttt cagataacga
    34981 aaatatcaat cctaaggtag tgtttaaaaa tatgaattat cctatccata agggagatat
    35041 tgttggtgtt gcaaagtatt ataatgactc tggtaaattt gttggaagtg ttgatgtaaa
    35101 aagtgaaagt aatataggat gtattccttt gaaggataag attaagatta aggttgctaa
    35161 gataaataaa aaacttgaga ttaaaaattc tgtttgtttt aaagcatagt aaagcatatt
    35221 attaaaaggg tatgttaaat ttataaagac tccactttgt ggagtctttt tgttttttac
    35281 aaaaaattaa aatagtggca acaattgagg atgtgaggga gagttgccac tattttgtat
    35341 agggtattat attatgtttt taagctagtt ttactatctt ctatgtttat ataataactc
    35401 ttgtgtgtga atttaattga taattaatat gaaaattatg tgaagttttg atttatttgt
    35461 aatatattct actactatta taatttttct actggatata ctaatcattt gtttaacatt
    35521 atctgagatt gatttgcaaa cttttatata actaaattag ttatataact tatagattcc
    35581 attaaatacc ctaataatca tatatgtaca tacaaagtca tgcttatgca aaatctgcag
    35641 tttcaactaa cttattatat aaaccatctt tatgtagaag ttcagcatca tttccagatt
    35701 ctattactct acctttatct aatacatata tattatcagc actcttaatt gttgaaagtc
    35761 tatgagctat tataataact atcttatctt gtatgtactc tttcaagttg ttcaatatct
    35821 ctttttgtga aatattatct agagctgaag ttgcttcgtc cagaataagt acctttttat
    35881 tacttactaa agctctagct attgatatac gttgtttttg acctcctgat attttgacac
    35941 ctttttctcc tactacttcg tccaatccct tatctagatt ttttataaaa tcatctaaac
    36001 aagtaacttc taatatctca tctaattctt tatcacttat tttattattt aatactatat
    36061 tattttttat tgtgtcatca aatacaaatt gatcttgagt tactatatca atattatttc
    36121 ttagtgattt taaattaata tcctttatat taacaccatc tattaatata tcaccttcat
    36181 ttatatccca aagtcggtat attagatttg ttattgttga tttgccacat ccacttccac
    36241 caacaattcc tgttacttcc cctttctcaa attgtaaatt tatatcattt aaaacaaggt
    36301 ttaaatcctc accatatcta aaagatacat ttttaaaatc tattttctta atttcactgt
    36361 tatctattct atatccatta ttatcaactt taatatctat cttttcatct attactgaaa
    36421 atactctatt gatagacact tttgattgtg ctattctagt attcgccctt actatagcta
    36481 tacatggtcc aattaacatt cctgtatatt gttgaaatgc tattaactcc cccatcgtca
    36541 tcttattatt tattatttta tatcccccaa ttccatatat taatattgtt atcaatcctg
    36601 ttagtatttg agatattgct atattactac tcataatgat gttcaaattc aaatcttttt
    36661 ttatcaaatc tctctctctc tttaaatact tattaaagaa attctttttt gaatttaata
    36721 taacaatatc cataatatta gatacgtact cttgaatcaa atttgataaa ctgcctgaat
    36781 cacttcttat ttcagaaatt ttcttagata taagttttgt cattttattt tgagaaaatg
    36841 ttaatatcaa ctgtaaaaat aaaactacta aaaataaatc aaactgcaaa ttaattaaga
    36901 aaattaacga tattatagct gtaaacacat ttacaataat atcaaatata atctctgctc
    36961 caaagttttc tatcataaat atatcacttt ccataatgga taaaatatta cctgttttct
    37021 tacttgaata atatctacca gaaagttttg atatatggtt aagcaacttt acttttagat
    37081 ttatagtaac tttatttttt attgaagtat ataaatatga taatataaca tcaaatgtag
    37141 ctgataatat ccttataaaa atatatatca atattaaatt tataagcaga aaaatatttt
    37201 tatttcctat tccatcatct attatacatc taattagttg aggtattaca atatttacgc
    37261 cagcaattat aaaaaccatt ataaatgata ctatcaactt agtcttattc ttatatacta
    37321 ttatatttag tattctaaat aaattattat taatagtttt tttcatctat ttttccatct
    37381 tttatagtta taattctatc agctgtcttt gcaatattat cattatgagt tatcataact
    37441 agtgtttgtt tgtactcttt aacacaccat tcaagcatat tcataacttc atttgtagtc
    37501 ttactatcta agttgccagt aggttcatct gcaaatatta ctgacggtct attggctaaa
    37561 gctctagcta ttgcaactct ttgttgttga cctcctgata gttcattcgg atatttcttt
    37621 atttgttttt caatccccaa cttattaatt aatctcataa catattcttt atcttctttt
    37681 ttcccatcaa gcaacacagg aagtactata ttatcatata catttataac tggtattaaa
    37741 ttgtaacttt gaaatatgaa gccaaattcc tgtcttctta tttcagacag cttatcatca
    37801 tttaatgtat ataaatctac atcatctaag tacacattcc ctaaagttgg cttgtctaag
    37861 cctgcaacac agtgaagtag tgtactttta ccagaaccac ttgcacctac aatagctgta
    37921 aatttatgtg gctctatatc taaatcaata ccatcaagag ctctaacttc attctcatat
    37981 tttccatata ttttttttaa atcttttacc ttaagtattt tcataacgta tctccattcc
    38041 catttaaaaa acatatattt ttaaattaaa ttttcgtaaa taagatctac tgccatatct
    38101 aaattctcta attgatataa gtatacttct ttgtagtcaa tactaatatt aaactcttta
    38161 tttaaaatag ttaaaaaatt atatgcatta taatttccaa tacatgtaaa attgttaaat
    38221 aaagaatatt cacttacaaa ttcaaagtct atttttattt tagaaaagtt tctatttatc
    38281 acatttatta ttttccttgc tatatccaat cttatcaaat tagatttata acttggagtg
    38341 ttcaagtttt ctatttttaa atcttcttta cttttgcttt tttgaataag tatttcttcc
    38401 aattcattaa acttaatata tggattgttt tttaatatat ttgcaacaat gccagttgcc
    38461 actgcacaag ccttactatt tttaccaaaa tgagttactt tatctttaaa tttaataaaa
    38521 ttatcttttg aatttgcata catttgaatc ttattttctg gttcgtatat atattgatta
    38581 tttttatata tattttcatt acctactaca ccaataacac tttcaaatat agtaggaata
    38641 ctttctttat cttcatattt attatgtttt gaacaaataa taaatctacc ttgactattt
    38701 aaaatattac aaaccttttc taattctttt tcatacatac tattaataga tgcagctgaa
    38761 atgtttatta tctgtatatc cgacatagtc aacttgctca gtgtactaag aagatttaaa
    38821 gaacttgttt ttccagaatc attaaatata ttaataggat aaatttgggt atttttactt
    38881 atatttaata tggttttcga tacaaaagtt ccatgtccat ttatgtcatt tatttccttc
    38941 ccccccaaat ctttcaattg aaaatttgaa tcataaacat aatttccatt aatatcatca
    39001 tcatttacat ctaatcctgt gtctaagact gctattctta ctttagtcaa ttaataatca
    39061 cctctaaaat aaattacctt gaatataaaa ctaatcctta ccataatata ggttccaaga
    39121 tgtttttcat ttttttacaa tttgcatcaa acattttttt gttatttttt aaagtatata
    39181 ttttcgatgg acaagttgta caaaataaat ttactttaca ttctttacaa ctctcaatat
    39241 ttactggttt taatttatca aatatattaa atatatccat ttctctatta agaatcctct
    39301 ctaatatgtt ttcattaaat tctaatatat tgaatatctt taaatcctta tactctaagt
    39361 ttggacacgg atatacatct cctttatgat ctatacttat ctgattaaca cctgctttac
    39421 acatatttga acataaacta ctttcatcca cataatcatc tttgcaaatg taatcaatat
    39481 caagtttatc attaagatat ttgctatagt tctcattacc tctaccaata ttcataaaat
    39541 ttcttattat aggcgttgta cctaaatctt catttaattt attgaatttc tctatgtctt
    39601 tctcattatt ctttcctacc accatagaca aacctacgtt ctcgaatttt tttagtttta
    39661 taagtctaat cacatttaat actttacaga atactccttt acctcttact tcactacaac
    39721 ttaattcatc ataaccatct aaactaattt ctattgcata taaaccatta attatatcat
    39781 caatctgttt ttctttaatt aaagttgcat ttgtagacag aattatttta cctttaaatt
    39841 tttcttttat ataatccaac agctctaaga aatcatttct catcaatggc tctccacctg
    39901 taatggttaa tatccttgga tttaatttaa ctatattatc tattactttt cttacttgag
    39961 atgtatctaa ataatcgtta ttatctattt tagaatctac acagcaataa tcacaactta
    40021 gattacatct attagttgga gaaaatgaaa ttttgtttat tctctctagt ctaaattcac
    40081 ttagaataga atcacttaga agtcctatat actctaactt atctataact cgttcataat
    40141 attttttatc ttcattttct tggaatacat catacaaatt accaagttgt aatgcattat
    40201 ctactgaata ctttagaact tcataacatt ctattggaat tttaacccat cttccattta
    40261 ctttattact aagaataact tgattattat ttattatttt ttcacatata caatctaaaa
    40321 aatatttgtt tgagctattc atttatttta tttccttcct atatatttaa attagaaatt
    40381 tcattaattt tcttttatac cacttactat actaagttta tttatcattt tattagaaaa
    40441 ataaactgca atgacacaaa caaaaacaga tatagatcca aatattagaa tttcatatat
    40501 tggaatttca aatttaatag agttatttat accatatacc tgttgattaa gtttgttagt
    40561 ttcagaaact attttataat aattgaaact agatataatt ccagctacaa tcatacttaa
    40621 taccccatat atcatatttt cttttattaa cattcttttt acattttttt tggacatccc
    40681 tattgctcta aatgtacata tctcactcaa cctcacaatt atatttgatc taactataaa
    40741 aataatgttt atagatgata ttaataaaac tccaaataca caaatcattg ctaatttata
    40801 tgaggattta ttataatggt ctccaaaatg attacgtaca tatcttccct ctatatctga
    40861 aaatccactt ttttctatta tattatttat ttcttttatt acttttttat ctgtttcttt
    40921 ttttatcttc acaaaaactt tattataatc acttatccct gttaattctt ttaaatcctt
    40981 ttcattaaat ataatttgaa ttccacctga ttgagattct ccatcttgct ctgatatata
    41041 gctatttttc attattccag cgattcttac ttttgtattt atatatttat actctccatc
    41101 tttatataca ggaattttta tatctattaa gtctcctatt ttaggtgatt ttataatctg
    41161 agtattattt gacaatttaa ttctagaata aaaattattt accaataaaa catttttata
    41221 atccctgtct gtataactat aaacattttc gcctttatct atatatttat ctatattatt
    41281 taatagctct ttattgtaac ctcgaattaa aactgtagac tcattattat tatttatttc
    41341 agttcttttt agctcatcta aataatcttc ttctaagtca gcatttctta gatatccttt
    41401 taaataaata ttgggttcaa catctgttac atcttcaata gcttttattt catttaataa
    41461 agaattatca tatttagaaa atgtataatt tgcatttatt ggtgaatatc ccaaataaat
    41521 atcaaaattg ccatatgatt tacttgttat attagctgaa tctgactctt ttccatatat
    41581 gaattttgta gaagttagtc tgcctataaa taaaacccca catagtgata tcgtaattat
    41641 tattattatt gatgtaacct tattcctaaa tatattttta aaagctatct catttataat
    41701 tccaacaact tttttatgtg attttaacaa caaaagccta ggaatataat ttaacttatc
    41761 tgtctttttt atagcatcaa ttatagataa atttccagct ttatatattg gtactacaga
    41821 ggctaatata actgctataa ttgacatgat gatagattca attatagagt ttgtatttat
    41881 agttaattct gcacttttat catatactat catgagacct aagtaagaaa aaactatacc
    41941 tccaagtaaa ccaattacta tacctacaga taaaactaca atactctgaa taaaaaatac
    42001 ctgtctaata tttctcttgc tagctccaac agctctaagt aaaccaattt gcttggtcat
    42061 atctagtatt attatgttaa acatattgta tattactaat gttgcacata ataaagggag
    42121 taagctttgc tttattgaat aagttgtttt ttttgaaata tttttcatat acatagacat
    42181 acttacttct gtatttggat aaaattgatt acttgttaac ttatattttc tccctagatt
    42241 cactactttt tgagaatcta aatcttttgt attcaatttt aatgtaccca tatgagttat
    42301 taattcatat ggaacaatat ctttgccatt gtttgaatat gtaaaagctc ttaccttata
    42361 tttatttaaa ttttcatagt attcatcaga tttacttaaa ataccaacta ttttaaattg
    42421 cttatcttta ctataaatag aattttcatt atttttattt atatgctcat taacaatctg
    42481 aaaatcaata gtttgattta atttgacatc taattccatt ttgtctaaaa ctttttgttc
    42541 tattactaat tcattagaag ttctaggctc tctaccttta actaacttat atctagtaga
    42601 atctaaaaaa tctttattgt aagagcataa atttagagat gctccattat ctttacttat
    42661 aatttctcca aatttaagta catcattgaa ttcttttata tcttcttcac cattaagttc
    42721 ttttactata tcactattta tatcttcata aaaagcatga taatctcccg agtttttgta
    42781 tgcatgattt atatctgatt gtccttgaga ttcattaata acacttaatg aaaaaactag
    42841 cataacagca atccctatac taagtattaa tgataaagtt tttccttttt gtctctttaa
    42901 atatgacacc gcaagtttaa tatttatcat aatcagaatc ctccttattc atatttacaa
    42961 gaaaaactct ataacctaaa atagtaggtt atagagcact attcattaaa tactaactaa
    43021 ctcgttgtgc tagttaaatt taattattaa aaatactaga gttgagaaaa tcacatttca
    43081 tttgtaaaaa actacatcta gtactttcaa catatttaat agactgatta gtatttttta
    43141 ataagctact gttccttttg gagttgatcc tgcacaatcc accatacagt ctatttgtga
    43201 aattattcca tgcttatcat aataccattt acatggatct gcttgcacct caacatcttg
    43261 aagttctatt ttttcttcga ttttttttat atgtatcata atacatatcc ccctttactt
    43321 ttgttttata tttattataa ctagttaaac tagattataa actacatagt ttttttgttg
    43381 tttccacata aactctttct aatccacaat aaattggtac tgcactttgg aatttacctg
    43441 ttaccttttt attgataagt ttacatctgg ttgacataca ataatcaagt ctagtacatc
    43501 catcacactc ttcattctta gatatataaa tttttataag gttcttaatt tttttatcat
    43561 ctaatccatc atatatattt cctagtaaaa tatctttatc tcctacacat actgtacatg
    43621 gatatacatc tcctctagta tctattgcat aactatttat ccctccaaaa caatctcctt
    43681 ttttcttatt tataaattgt ttatctaaaa tagatatatc tatatcagga taatcctttt
    43741 taatattcat aattttacta atttgttcat ttaatatttt aatatgagaa ttatcccaat
    43801 ttttatccat aaaatctgaa attggtgcga tatttttaaa cccttgtttt gctatatcat
    43861 atacactctc ataaagatac ttaacagtat ttgagttata tgtcattctt gccctaacat
    43921 atataccttt atctataagt ctttttccat tttccattac tttttcataa gtacctactc
    43981 cattagcatc tattctattt atatcatgta tattcttttt tccatcaata cttatcgata
    44041 tgttttttac attctttgct ataaactcta ttatttcatc atttataata gttccatttg
    44101 tagttatatc aaataatatc tttttgtcac tcaatctatc tactaaatcc ctatgtatat
    44161 atttaatcaa atcaaaattt ataaatggtt ctcctccatg taaaacaatt gttgtataat
    44221 cactattact ttctaattct ttattacaaa taaaatctat tgttttatca gcagtttcat
    44281 aactcatatt ttcttttttt ttatcattac cttcataaca atatgtacat ctcaaattgc
    44341 agtcttcagt tacaaatata gtaaatttca attaactttt tcatctcccc atacagctgt
    44401 atttaaattg tgtttcatca tactacacca tctatccaat tccaattcat tatccttaac
    44461 tgaatctaat atcgctgggc aatgccaaca aaaaatattt acatcacaat ctttacattt
    44521 ttcaaagtta tatggataaa tactttctaa tttaatcaaa gactttagat ctcttgtttt
    44581 attttctttt ataactttta caaattcatt gtcaaatata tttcccattt tatagtcatc
    44641 ctttatcagt gaaggacaag gatatacatc tccatcataa tttataaata tttgagagtt
    44701 tcctgcatta catgcacaac atcccatttt tttatttttt ttatctttac acatttttaa
    44761 ttcattatct aaaatatacg gaattgtaat tggaagaact gtatcttcaa ttaaatagct
    44821 ttctttattt tctaggcctc ttcctgttgg aataaaatat ctttcaacaa attctgttcc
    44881 aagcttttta tttaaatctt taaattgttt atttaaatga gaattttttt gtccaaatac
    44941 catagacagc tttatattac tgaatccatt gtcttttagc agattaacag agcttattac
    45001 tttattaaat acaccttttc ctcgtgtttc actacaagta ttttcatcta ctccatcaat
    45061 actaatatct attttttcaa aattagttat aataaaatca acattatgtt catctattaa
    45121 agttccattt gtggataata ttaatttggt atcaggtaat ttttgtttta tatatttaat
    45181 tatttcaaaa aaatcttctc ttatcaatgg ttctccacca gttataatta tatgaggagt
    45241 atttaaaact gatattatat ctacgatatt ttttaaatca tatgtactaa gtaaatcttt
    45301 cttattagaa gaagattcaa cacaacaatg tttacaaaat aaattgcatc tatttgtcaa
    45361 acaaaaataa attgcaacac cattgcttaa catatcaaag tttaaattgt tacttttaaa
    45421 aatttgattt ttgttcataa tatctataag attaataata tattttttgt cactttcatc
    45481 atcaaaataa tttacaaaat cataaatttt tattttattt tcttgtccta aaagaaaata
    45541 cttatatatt tcttcagaca atttaatata ttttctaaat ttcttattat aaataattac
    45601 tagttgattt tttctataaa taattaaatc ttctacatta aaaatcattt cttcagaatc
    45661 tatcacaact aagtcctcct caaattagta aaatattttt ctttaatatt tattactaat
    45721 atcaacttta ctatctaatt agttatttaa ttgttgtttt tatgttccta gttataaagt
    45781 ttatcaaatt tacattttat ttttttatac tatatagaac ttttggtcaa taatgttacc
    45841 atactaaggt cgcatttgca gataaaaata actctatttt tctaaattta tttaagatat
    45901 atcatgcaaa taatataact ataaaaccta tcaacatttt aaattcaaac aaatataaat
    45961 cacatttttt gttctattat tttattgagt actaaaaagg atgttatctt attagcatag
    46021 cattcaacca tttttatcac ctccaaatat cctatgtctt aaagatagca tcttctattt
    46081 tatctttcaa tactactgct ccaactgggc aatttagagc cccaactaga attagttcct
    46141 agttaatggt atataaatag taattgtaaa cttgttttta tctgagtata tttccacatt
    46201 tccattatat ttttctactg aactttttac actacttatt cctattccat gtaaaaagga
    46261 atctttctta cttgtaataa ccttattatt ttttaataca acttcattta tctttgtatt
    46321 ttcacatttt attacaaata acctatttat aacagttcct cttaatttaa tctttttttg
    46381 tatacttgtg tccttaatct taatacaagc ttctattgca ttatctatta tatttgaaaa
    46441 tatactacat atatctggca tctctataaa attacattct aaaaaattaa tatctactag
    46501 aaaatatata ttattcatat cacaaataga ttttttatca cttaaaataa catctagaat
    46561 catattctga gtattaaata tagtattaca ttcttttatt tgcttattta tatctttaat
    46621 atacttatct gcaaactcat ttttcccata aacattctga atacaaatga tatgattatt
    46681 catatcatga tatagttttc ttattttcaa ctgatattcc tgtaaattta aataatattt
    46741 atattgcata ttcattcttt tttttgtaat ttcatattct atctttaaac tattatcttt
    46801 tattattctt cctattatgc ttactaatga aagatttgat agtaaaaata cagttgatat
    46861 tgtaagtatt attaaactct ctttagaatc gataatctta tctttaaaaa taaattcaaa
    46921 tattactatt acaccaataa tgtttgctat taatggaata gataaatata tacaatccct
    46981 cttgtttatt tttgttttta atctgataaa cttaagcaat ggtattaata ctattagtaa
    47041 tgatttagat atcattatta actctaactt caacaaatta tcctctaata aatcattcat
    47101 attttttata gaattaagtg tcattactat acttaatcca atactatcaa atccaattaa
    47161 taacatccaa tatagcaaac ttataaatac acttttccat ttatccacta cataatttat
    47221 tttatacaat acatatgtaa taaatataca tataaataat ttaatattta tattaaactc
    47281 aattgtattc aacatagtaa ttatcataat agcaattact atgctactat ttagggttaa
    47341 tctattcttt cttaactcac taaattcatt taataaaaat tttaatacaa tccattctat
    47401 cgtcgtagaa aatataggta aaaaaatcca aaatacattt atatttaaca taatacatct
    47461 cccaatacat atgttaattt tttctttaaa ttagccattc tatatttact aactggtata
    47521 tctttaccat taataactac agtattttta catataaatt gaatatactc caaattaatt
    47581 aaatagctct tgtaacattt ttaaaaattt attctttctt aaatcactga attcatttga
    47641 taaaaatttt aatacaattc attctatcgc cgtagaaaat ataggtaaaa aaatccaaaa
    47701 tacatttata tctaacataa tacatctccc aatacatatg ttaatttttt ctttaaatca
    47761 gccattctat atttactaac tggtacatct tcatcattaa taaccacagt atttttacat
    47821 ataaattgaa tatactccaa attaattaaa tagctcttat gacatctaaa aaaattatat
    47881 ttttctagct ctaattctat tttatccata ctatttttag tataataagt atcattttta
    47941 gtatgtatag tcaaaacctt tttcctaacc tctatataca taatactatt aattaaaatt
    48001 ttattgatta tacctttatt ttctatcagc ataaaatttt ctcttttttt tataatatcc
    48061 gatatacaac tcaaaatact ttcatttaaa tctccaaaat ctataggctt taataaatat
    48121 ctataagccc ttaccttata gccttcctgt atgtaatcaa ctattgaagt tataaatatt
    48181 atttcagaag tatcattagt ttctctaatt attttagcca catccatgcc tgttagttga
    48241 agcattttaa tatctaaaaa aaatatatca ataccttcta aatttgtttc caataattct
    48301 tctcctgaat taaactcaaa tagttcaatt tgactagaaa taccctctaa ggactttaat
    48361 atacactctc ttaaaaaagc tatttgtgta atatcatcct cacagataac tattctatac
    48421 ataaacaccc ctccttagac attagatctg aaaacaaata aaatatcaat ttataaataa
    48481 ttatttagtt atacaactaa catggtcatc aaatactatt attcacttaa aaaatcaccc
    48541 cctattttta gtatgttaac aacaaaataa gaagatatct tagattttta aaaacaatta
    48601 atacttaatg tagttttgta tactatttat aggtaatttt ttatatcatt ttaaacatta
    48661 aaattattga tgtttaagaa ctattatatt gatagtaata tataattaat gatatcaaaa
    48721 atttttaatt agacttctct cttattcaag atttttctat ataaaatcta agaataaata
    48781 gaaaactaac atctaacctt ttatttttta ttttcgatct atttacttga attttaacat
    48841 aaatctatct tttagtatat attaatcatg ctgaatttgt gatgacatgt atacaaaata
    48901 tcgtttagta ttttctaata aaaaatatta ctgaaattaa aaatctacaa tagcatttaa
    48961 caagtaaaaa catgtttaca caaatatata atttaaggtc tttaaaatag agtatgtatt
    49021 attctaaaaa ttagttatag ttatcacata aaaatagaaa agaattttca aaagatttaa
    49081 agaacatata tacttcaatt gcagaagatg taatgttaag tgaactagca ttcttcgagg
    49141 aaaaatagac tcaaaaaatt agaaaataga atcaggtttt agatgattta agtatttatt
    49201 ttcaaaaaag aaatttgatt ctaagttaat aaagaaatat ttaaaaaaat caaaaaattt
    49261 tcttaaataa gtaataggtt ttgtaaaaat ggaaaaatat caaaataaga ctatgatttt
    49321 taaaactata gccttatcaa taaattttta tttaaagaac acacataaat atttttaaac
    49381 ctaatttatg tgaagtttta tgtatttttt atataagtag tattctaatc ttactcatct
    49441 aatataccaa aaagactgta agtaagttca cttttatgca aacttaccca caatctcttt
    49501 tacacattaa ttctatttat taaaattaaa aatatttact gctattctac ccaataaaga
    49561 tgatactgtt gttgttctgg ctggtactgt tacttctatt tctcctgtat ctgctgtttt
    49621 accacttgat gtgtgtgtca ctgtaaatac taatgttact tttgtttctg tatctggtgg
    49681 cactattgtt ccatctttc
//
LOCUS       DAEPXW010000018        49382 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.018, whole genome shotgun sequence.
ACCESSION   DAEPXW010000018 DAEPXW010000000
VERSION     DAEPXW010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49382
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.018"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            263..2275
                     /locus_tag="KRM55_001022"
     CDS             263..2275
                     /locus_tag="KRM55_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1593279.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DLINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLIITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            complement(2611..3801)
                     /locus_tag="KRM55_001023"
     CDS             complement(2611..3801)
                     /locus_tag="KRM55_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1593280.1"
                     /translation="MSKVKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPAGKRDDISLREKEKQIKKDLDDGIDTVGGKMTVCQLYEKKNNQRKNIKRN
                     TKIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFNFKLSDVLEDDTEAKVILTPEQEEKLLAFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISTPKTKNGKRELPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     RLAS"
     gene            complement(3879..4082)
                     /locus_tag="KRM55_001024"
     CDS             complement(3879..4082)
                     /locus_tag="KRM55_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1593281.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRRLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(4455..4709)
                     /locus_tag="KRM55_001025"
     CDS             complement(4455..4709)
                     /locus_tag="KRM55_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1593282.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLVFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            complement(4712..5131)
                     /locus_tag="KRM55_001026"
     CDS             complement(4712..5131)
                     /locus_tag="KRM55_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1593283.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            complement(5398..5628)
                     /locus_tag="KRM55_001027"
     CDS             complement(5398..5628)
                     /locus_tag="KRM55_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593284.1"
                     /translation="MIGLKRRNMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            complement(5652..5843)
                     /locus_tag="KRM55_001028"
     CDS             complement(5652..5843)
                     /locus_tag="KRM55_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBH1593285.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCIRKIDLIFEKED"
     gene            complement(6007..6723)
                     /locus_tag="KRM55_001029"
     CDS             complement(6007..6723)
                     /locus_tag="KRM55_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1593286.1"
                     /translation="MEYIRSKKYFTPDLQTKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFVYITVPGMKKDCHEKLPEELL
                     LSWTPEELDYIHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            complement(6757..6843)
                     /locus_tag="KRM55_001030"
                     /pseudo
     CDS             complement(6757..6843)
                     /locus_tag="KRM55_001030"
                     /inference="COORDINATES: protein motif:HMM:NF025568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6845..7471)
                     /locus_tag="KRM55_001031"
     CDS             complement(6845..7471)
                     /locus_tag="KRM55_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1593287.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKDYQVPESTIEVTPNAYRNTTIGSLITFTLAQYDFW
                     VTDEFASNFRKMLILEQYRNLKMNVLYQKCLVNGPISYIEDIFNEMIKKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKSQLTTHVNQFVKKYITIEKVK"
     gene            complement(7761..7901)
                     /locus_tag="KRM55_001032"
     CDS             complement(7761..7901)
                     /locus_tag="KRM55_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593288.1"
                     /translation="MEQYWWIIIVVVLIVVGLLKIVIMKKYNQRRNSNNRSKDSEDDK
                     MY"
     gene            complement(7953..8864)
                     /locus_tag="KRM55_001033"
     CDS             complement(7953..8864)
                     /locus_tag="KRM55_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1593289.1"
                     /translation="MEKGRLLQNKNMNKAIQVSKITLIINLSLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVVSTIVVMVGIKISEKQPDREHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVPSGIALTAAVLSIVIKEWMYWFTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALNIFKESINKMVDHS
                     CDNATETRIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELLYSA"
     gene            complement(8876..9574)
                     /locus_tag="KRM55_001034"
     CDS             complement(8876..9574)
                     /locus_tag="KRM55_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593290.1"
                     /translation="MKKILSSTIQIFKQIKSDPMMFAACFSPFIMGTLIKFGIPFLER
                     ITKFSLQAYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPTPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            complement(9571..10254)
                     /locus_tag="KRM55_001035"
     CDS             complement(9571..10254)
                     /locus_tag="KRM55_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593291.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALPEHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKISEYILSKTVALIAISTV
                     IALILGVVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIVCFV
                     PPIVGLFVKLPYLFRFFPFTACMNLITGKSVLLSFDMVLVIATLIILYIVARHTVEHM
                     WKSLGGVKL"
     gene            complement(10251..11096)
                     /locus_tag="KRM55_001036"
     CDS             complement(10251..11096)
                     /locus_tag="KRM55_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593292.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KVLTGLNTRYKGSVKVAGTEIREHTNQFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     EKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNSRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIQYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            complement(11200..11781)
                     /locus_tag="KRM55_001037"
     CDS             complement(11200..11781)
                     /locus_tag="KRM55_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1593293.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFALHGLKKVTVDDLAAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTIKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEDLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMIQNLLVNGIIQQVVAE"
     gene            complement(11859..12716)
                     /locus_tag="KRM55_001038"
     CDS             complement(11859..12716)
                     /locus_tag="KRM55_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1593294.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIETFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPTWSHRFMGLIQWGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVASLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPQKELLALELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            complement(12929..13540)
                     /locus_tag="KRM55_001039"
                     /pseudo
     CDS             complement(12929..13540)
                     /locus_tag="KRM55_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(13491..14231)
                     /locus_tag="KRM55_001040"
                     /pseudo
     CDS             complement(13491..14231)
                     /locus_tag="KRM55_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
     gene            complement(14699..15133)
                     /locus_tag="KRM55_001041"
     CDS             complement(14699..15133)
                     /locus_tag="KRM55_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH1593295.1"
                     /translation="MINIKDINYVPNISEISVYIENSAFDELYQHMNNEYKAVCKIEY
                     SKDVWARGWNVKFKKSGKSLCVVYPKKNYFTVLVVVGNKEKEDVENLLPRLSEYVQEI
                     YRNTREGNGQRWLMIDLKSKNNVYQDVLRLIEIRYAIKCVKP"
     gene            complement(15193..16122)
                     /locus_tag="KRM55_001042"
     CDS             complement(15193..16122)
                     /locus_tag="KRM55_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1593296.1"
                     /translation="MYAYENIEMSLNYIEQHLSEKIETEKLAEIACLSTFYYQRLFKR
                     LVKKSVQEYIKLRRLAMVIAELNNSEERILDIALKYGFSDHANFTRAFKEVYHITPDE
                     YRKNVPMLNTFDKPELSSRYIMIDENVPLIVGNIVLEIQRKTLRTKETYFGFEKTVNI
                     AEQIPAGESTGIDVPGQLWREFHAKKLQTENAIFNNDIELGVSHLASPDKGTFLYFAG
                     GMVSSTDVCSKNMVQHTLPAGEYIVCKIEAESFEELVTTALNQANKYLFETWLPNHKL
                     VTKPFMAEKYYKGNAEISYMEIWVIPVETVNAK"
     gene            complement(16389..16940)
                     /locus_tag="KRM55_001043"
     CDS             complement(16389..16940)
                     /locus_tag="KRM55_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1593297.1"
                     /translation="MSLQDYIFEKPVIETEHLILRTMNKNDIDDLKEWISDISLYEYW
                     GKRPSKSEKNPELLFNKPEKATKSFHWGIVHKQDSKVIGELWIYLIENDRMAKVAFRL
                     SKQYQGNGLMSEVLKGVIEFCFSKTELQKIWTDVHILNHASYKTLEKVGFQREGHIRE
                     GKMVNTYCDYYLYGILKSDYIIS"
     gene            complement(16954..17430)
                     /locus_tag="KRM55_001044"
     CDS             complement(16954..17430)
                     /locus_tag="KRM55_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1593298.1"
                     /translation="MTTYKVNSIGTIYNNEKGAFIQLEAPYILALKELDGFSHINVLW
                     WFSNFDNADFRSVLETDQPYKKAPEKMGIFATRSPVRPNPIALSAVEIINIDYMSGLI
                     QIAYIDANDKTPILDIKPYTPSLDRVENPQVPDWCSHWPHSLEESASFAWENEFNF"
     gene            complement(17511..18326)
                     /locus_tag="KRM55_001045"
     CDS             complement(17511..18326)
                     /locus_tag="KRM55_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH1593299.1"
                     /translation="MFKIGEFSKLTQVSTRMLRYYDETGLLKPAKVDSLTGYRMYSAE
                     QISTLNRIIYLRDSGFNVAEIALALDCSNDTIIEQLDKKSIEIMDNIQKEQEKLKKIE
                     IAKKELLHGKSELYFNITIKEIPSYCVLSLRKEIPNYYYEGELWKELSAFAKENKINI
                     SDETFSIYHNEEYKEKDVDVELCAIVNKIGKATGDFKFRFTEAVSMMACTMVYGDFSN
                     ISYAYRSFAKWLQENSQYKMKGSSRQIVHRGPWNEKNPENYLTEIQIPLENLL"
     gene            complement(18429..19331)
                     /locus_tag="KRM55_001046"
     CDS             complement(18429..19331)
                     /locus_tag="KRM55_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1593300.1"
                     /translation="MFKKNKKPTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDMHTVHETETIQLRLTDTNGIENFVKNFAKSYYTWNNSKEAIEARTQAISD
                     YLTKELQDLNVDTIRTDIPTSSAVTDVIVWSIEQLGTDTFSATYEVDQQIKEGEQATA
                     VKATYIVKVHVDADGDMVIVQNPTLAPAVEKSDYEPKTPETDASVDADTVNDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLEPIGRDYLYSELVNPVFTKDGDNVKVKVAVKFLDN
                     QTKATQVSQYELVLHKDSNWKIVG"
     gene            complement(19347..20354)
                     /locus_tag="KRM55_001047"
     CDS             complement(19347..20354)
                     /locus_tag="KRM55_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1593301.1"
                     /translation="MKLKHIAIIGSLFPILFSVVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGINDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     SEALKYQGWKYVYGGSNPNTSFDCSGLTQWCFGKAGISLPRTAQTQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYADLNSSYWKQHLIGAGRVK
                     Q"
     gene            complement(20351..22534)
                     /locus_tag="KRM55_001048"
     CDS             complement(20351..22534)
                     /locus_tag="KRM55_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009757268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1593302.1"
                     /translation="MKERIQSAFTKKKMFRFLKITLFAVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWAWLPWNWLDGIGKSVQYGLYCITNFVWMI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGQSIQTLAGVTSSGFSTSGFYVGFLLLIIL
                     VVGIYVAYTGLIKRETSKALHAVINFVVVFILSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIENNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNANDSQSMGRRIFRRP
                     YLYMAHRARRMERRLAGAVTAGGVAGAVAGSTVSNARTTRNNSAKENRGNTSSSMGQR
                     AGSKLGAVLDTKNKVKDKANAMKEMVKDMPTQTAYAVHSAKEKAKTSVSDFKRGMVQE
                     QQSRQSGRLEKQEQHKKTIADKRMELQKAQEARQARKTDGSATTGATRPHERPATASK
                     LSVEKTHEVKRPAITSTSKAGEPVKTNSVKERPLSSGASDGKTPQSAQPVHRKNVEKV
                     VSQETRQNYKAERTTKAQTFEQAKHTTEHTEKNRNLVTKKGQKKK"
     gene            complement(22534..24984)
                     /locus_tag="KRM55_001049"
     CDS             complement(22534..24984)
                     /locus_tag="KRM55_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1593303.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKRLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNLKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLTEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVVEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVIRVSADDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSETRGLLHVIDELRCEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPIQRNEVE"
     gene            complement(24971..25360)
                     /locus_tag="KRM55_001050"
     CDS             complement(24971..25360)
                     /locus_tag="KRM55_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1593304.1"
                     /translation="MKKIRSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPAFLTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLQKEIFNETITAVRSVNYVPD"
     gene            complement(25469..25972)
                     /locus_tag="KRM55_001051"
     CDS             complement(25469..25972)
                     /locus_tag="KRM55_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1593305.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIEIGEYVSIEELNEMYEMIEELPDYIVDCLDEFIGHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYFYIDELQALGDIPPNLQNYIDYEAFGRDLDMGGYFIETSR
                     GMCEIPY"
     gene            complement(25990..26493)
                     /locus_tag="KRM55_001052"
     CDS             complement(25990..26493)
                     /locus_tag="KRM55_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1593306.1"
                     /translation="MQETRVLVETSGTTGEETTSYWFDLPIEVAEFEEKLGVGAESGE
                     YRIIEKVLPFADEVHEHTTVYQLNELDYMYRQLSSDIQEEYTALHTVFENLEALYICR
                     NVITIYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAFSLHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(26412..26708)
                     /locus_tag="KRM55_001053"
     CDS             complement(26412..26708)
                     /locus_tag="KRM55_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1593307.1"
                     /translation="MNDIFRDIQAKVGCENISDLPSYKRKVWHEMKQLNLADYEEKQL
                     EDFSNYVFGMSCQTLKDVMKQQKGREEQCRKQGCWWKRAEQLAKKQRHTGSTCR"
     gene            complement(26791..27432)
                     /locus_tag="KRM55_001054"
     CDS             complement(26791..27432)
                     /locus_tag="KRM55_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HBH1593308.1"
                     /translation="MEYKYTKIDLEKWNRGKLFQSYIDDMRIVMSLTVDIDVTNLIKF
                     SKSHDLKFYPAMIWVVSKVVNEHDEFKYSWDNKGNLIKWDYISPSYTEFHKEDENFTK
                     TVTDFSDSIFEFHARFMLDREKHKMERAFVANQPLNFFDVSCLPWVKYNHFDVHVFDE
                     GKFLAPVITWGKYELERERYIMPLTMNIHHAVADGFHLSRFFNEVQELINSIS"
     gene            complement(27638..27859)
                     /locus_tag="KRM55_001055"
     CDS             complement(27638..27859)
                     /locus_tag="KRM55_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593309.1"
                     /translation="MNFGQNLYTWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(27860..27994)
                     /locus_tag="KRM55_001056"
     CDS             complement(27860..27994)
                     /locus_tag="KRM55_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH1593310.1"
                     /translation="MWELLKDFLLVSFGMGIGVVLMCILTVGKEADYEMKKLKESEDN
                     "
     gene            complement(28002..29201)
                     /locus_tag="KRM55_001057"
     CDS             complement(28002..29201)
                     /locus_tag="KRM55_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1593311.1"
                     /translation="MNETDFLTALKEKRCAYSVSQTRLAIMANISREHLSRIEAGKVT
                     LTEDMKHTLLEAVEKFNPDNPMFLLFDYVRIRFPTMDIKHIIKNILKLNIDYMLHEDY
                     GHYKYTEHYHIGDVFVYVSQDEEKGVLLELKGKGCRQFESYLLAQERSWYDFFTDALV
                     EGGVMKRLDLAINDRTGLLDIPELIRKCENEECISKFRSFKSYGSGELVKHNETDKYG
                     MGHTLYIGSFSSEVYFCCYEKNYEQYAKLGIPIEEVPIKNRFEIRLKNERAYYAVVEL
                     LTHYDAELTAFSIINQYIRFADKEPDKRKSDWKTNVRWAWFIGEGRSPIKLTTKPEPY
                     TLERTLNWLQRQVAPTLKMLKQIDKDNQTEYLETIEKQAKLTVRHYQIIKQQTATVEE
                     MVAKTKE"
     gene            complement(29403..30797)
                     /locus_tag="KRM55_001058"
     CDS             complement(29403..30797)
                     /locus_tag="KRM55_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1593312.1"
                     /translation="MKMILNKGHRIRASDKNLVYHFSIGTLLFVFIAVILLLNMKQLM
                     RTDWEHFSLLDNGLTLSTYNFITLLIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIIWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTMLYDMIANRITIDEVKAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            complement(30914..31399)
                     /locus_tag="KRM55_001059"
     CDS             complement(30914..31399)
                     /locus_tag="KRM55_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593313.1"
                     /translation="MAKEKGSFKEFLSAIAPEHQAFVEKLNTKLIEQGCDLVIKEAKS
                     GYTASYQLEKKTVMNWVFRKTGVFARIYGDNAGKYEDIIASLPADMQKKMTTSRDCKR
                     LIDPNACSDTCVKGFVYALNGDTHKKCRNDGMLFVLTNETAEHIAGLVCAEVNVRKSA
                     L"
     gene            complement(31497..31880)
                     /locus_tag="KRM55_001060"
     CDS             complement(31497..31880)
                     /locus_tag="KRM55_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1593314.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRAENDDGSTSEEITRRT
                     YDLKCSVQERMIQVSIPADIPVKDYPYNAEVELVNPVADTVANASYRGVNVDWYIKAD
                     DIILKNKGGQVGNPQNHAPQGQPKK"
     gene            complement(31895..32221)
                     /locus_tag="KRM55_001061"
     CDS             complement(31895..32221)
                     /locus_tag="KRM55_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1593315.1"
                     /translation="MELKYVVPNMAQTFGNLEFAGENKIEQQRINGRFTPVSRSYNLY
                     SDVQRADDIIVTIPAKAGEKHFKPEQRVKLINPKITADGKAVKGRGFTNYILTADDML
                     PAEESK"
     gene            complement(32457..35501)
                     /locus_tag="KRM55_001062"
     CDS             complement(32457..35501)
                     /locus_tag="KRM55_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1593316.1"
                     /translation="MKKILKRLCMGVLAFATVVTALPTTLVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSIEYVKQYTASHNGISNNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSNNTSITNGNG
                     NYSIAGATYGVFSDKDCTKQIATLTTDDSGNTEVAEVKATTVYIKELSAPLGYKVDTT
                     VYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKSNPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTTAETDSNGTTHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKSPTGYLLDGAYMQANGSEEQIKALYLTQITEDGDLAVLTGSNQFSVSDE
                     VIRGGVKIQKRDLETKDTKPQGSATLKDTAFDIISLNDNAVLVEGKIYKKNEVVKTIH
                     TDIEGIASTSADLLPYGNFRIVEKQAPNGYLTDGAKTIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSSKWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGMELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEITIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAEIIIDGKRVESDYTFVADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LEGLEVGTKYKLVGWQMLKEENAELLINGKRVESDYTFIADSETMKVEVTFTFDATSL
                     DGKQLVTFEELYDLSNPNEPKKVTEHKDIEDEGQTITFKEKPEVPEKPETPTTPEKPS
                     RPTDSPKTGDNTNVMAFLVMLLTSAGGLAGTYLYKRRKMKKS"
     gene            36002..37222
                     /locus_tag="KRM55_001063"
     CDS             36002..37222
                     /locus_tag="KRM55_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1593317.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHISDENYPAVINEKELVDTVISSTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEKKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            37259..38608
                     /locus_tag="KRM55_001064"
     CDS             37259..38608
                     /locus_tag="KRM55_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1593318.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            38722..39284
                     /locus_tag="KRM55_001065"
                     /pseudo
     CDS             38722..39284
                     /locus_tag="KRM55_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(39392..41725)
                     /locus_tag="KRM55_001066"
     CDS             complement(39392..41725)
                     /locus_tag="KRM55_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1593319.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSSLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEAAHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(41722..42405)
                     /locus_tag="KRM55_001067"
     CDS             complement(41722..42405)
                     /locus_tag="KRM55_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593320.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            complement(42476..43717)
                     /locus_tag="KRM55_001068"
     CDS             complement(42476..43717)
                     /locus_tag="KRM55_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1593321.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            complement(43728..44414)
                     /locus_tag="KRM55_001069"
     CDS             complement(43728..44414)
                     /locus_tag="KRM55_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593322.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKILLTVR
                     RMGYKWNVIK"
     gene            complement(44652..44996)
                     /locus_tag="KRM55_001070"
     CDS             complement(44652..44996)
                     /locus_tag="KRM55_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593323.1"
                     /translation="MYCLSVVLAIYGIYVFINCTEYIYTMLSTKHLTVKGNEYTIINY
                     YMSNFSQYIIFAILLASMGFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGNIENSILKK"
     gene            complement(45327..47834)
                     /locus_tag="KRM55_001071"
     CDS             complement(45327..47834)
                     /locus_tag="KRM55_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593324.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQIMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSIIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            complement(47843..48505)
                     /locus_tag="KRM55_001072"
     CDS             complement(47843..48505)
                     /locus_tag="KRM55_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593325.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
BASE COUNT        14994 a         9500 c         7600 g        17288 t
ORIGIN      
        1 ttattaaaat aaattttttt gggtgtatat tataatttaa tcgaatagaa atgaaaaata
       61 tacatacagt ttaagtttta agcaacaatt agggggattt ggtgacaaga tttttaatta
      121 taagaaagaa agtgtcttaa tgcaactttt ataaagtcat tatagacact ttctttttta
      181 tttgataaat ttaaattatc aaaattatat tgctttatac aactattttg ttggaaacta
      241 tttattatat aaggagaaat aaatgaaaaa atcagtagct ctggtaaatg atagtagaaa
      301 agatttaata gactttttag aaaataattt gaaattagtt tttggagatt ctataaatat
      361 taatagatac ttcataaatg aaataaatga taatgatctt ataaatgatg atgtaatatt
      421 agtaatgtca gtagaaagat tagacaaaat tataaataat atactagata agaaaaaagt
      481 gattgtggta agaagaactt ttagggaaga taaaatttat aatctactat ctttaccaca
      541 gggtacaaac gttctaatcg taaatgattc tgatgaaact actctagaaa ctataagttt
      601 attttataaa attggagtga ctaatattag accaattcca tatatgaatg ataataacta
      661 taaaaatata aaaatagcta taactccagg agttccagaa aaagtaccta gctttatctc
      721 agatatattt gatttaggtc acagatatat agatatctct acatttatag aaataataaa
      781 tttattacaa attgattcaa aggaaataca atctaatcta gttaaatact cagaagaaat
      841 aataagttta gatactggta taaaagataa atataaggaa ttatttttaa aaatagaaga
      901 attagataca atcttgaatt tatcaaaaga tggtatatta tttacttcaa aagatggtga
      961 aataaataca tataatagta aagtaaaaga tattttagac ataaatgagg atatatatgg
     1021 aaaatacatt gaggatatat ttgtagatag tttaaaagtt ttattgagtg agaaagagat
     1081 actagataaa gttgtcgtat tcaataagaa atatataaat gtaaataaaa aaaacatata
     1141 caatagagat gaaaaaatgg gcacatatta tagtttacaa gaaataacat acataaaaaa
     1201 attagaacaa aatctcacta aaaaattaag agaaaaagga caaatagcaa aatatacatt
     1261 taaggatata aaaacaaata gtcctaaaat gtttgaatgt atagatttag ctaagaaggt
     1321 ttctaaatct gacttaagca tacttatcag aggtgaaagt ggaactggta aagaactcat
     1381 agctcagtct atacataaca actcaaatag aaaaaatcaa ccctttatag cagtaaattg
     1441 tgcagccgtt cctgaaaatt tattagaaag ccagctattc ggatatgaca agggaacttt
     1501 tactggaggt ctaaaagatg gaaaacaagg attatttgaa cttgctaata atggaacaat
     1561 attcttagat gaaataggcg atatgccttt agaattacaa acaaaactac ttagagttct
     1621 tcaagaaaag cagataatgc ctgttgggtc tcacaatgta attaatatag atgttagaat
     1681 catatctgct acaaataaga atttagaaca aatgattgat aatagccaat ttagagagga
     1741 tttatattat cgattaaata caattccaat aaatatacct cctctaagag aaagaaaaga
     1801 agacatatta attattatgg aagatttaat taataagaaa ttaataatca caccagaagc
     1861 aaaaaaactt atacaaaact atatgtggaa aggtaatata agagaactcc aaaatgttac
     1921 atcctattta aacattatgt gtgaagatat tgtattagag aaagatttac ctccaaactt
     1981 aaggtcttca gataacaaaa atacatcatt aaaactaaaa tatagtaaga atgatatatt
     2041 gaatatatta gagatactaa ttttaaataa ggaatcagat gttggtattg gtagaggatt
     2101 aattttaaaa gcactactcg ataagaacct tcaaattaca gaaggaaaaa ttaaaaaaat
     2161 atttgaatat ctaaaaaaag aagaacttat aatttgtagt tcaggaagat atggaagtaa
     2221 aataactcaa aaaggagaag atttttacaa taaattaaaa tataaaggtc tataaaatta
     2281 taatttatca aacaaagaaa tctattcagg attaaagtac tccttcaata ggttttttta
     2341 tttttcaagt accctaaaat tataatttat tttgtacata aataatagga attaatagga
     2401 ataggataat ttttttattt cctatttttt aaattaaaaa cttactaaat ttctgattat
     2461 cttttcataa gttggtaaat gccgatatat cccatatttt cgggctttat tggcattttc
     2521 cttttggaag atacctcgca taagatggca tttaccagca tgaaaatgca accaaaagta
     2581 gtaaataagt agtaagatac attttcgata ttaagaagcc agcctttcta attcagcctt
     2641 tgcagactgg aaagtaccgt gagcataata ccctaatgtc atggttatgt ttgcgtgccc
     2701 catgatgtat tgcagggtgt tagggttcat tcccttattt gccatgttcg tacagtaagt
     2761 atgtctgaat gaatggggcg tgatgtttgg caacttgtcc ttatgcgtct tgttgtactt
     2821 cttaatcagc ccacgcacca tactttcata atttcctgcc acctttggca atccctcacg
     2881 gttcaagaac aagaagttgc tgtaaccgtc aacaacaagc ggttgtgctt ttcctcggtt
     2941 ctttaaaatt cgttcaagtg cctgatatgc tctttctgtc aatggaagct cacgcttccc
     3001 gttttttgtc ttaggtgtgg aaatatagta acccacctct gtatcacgca atagctggtg
     3061 gtctatgtta atcacacggt taagcatatc aatgtgtgtt gtcagtccgc ataattcaga
     3121 gatacgaagt cccgtttcca gcagaagaat aacttcatca cgatacttgc tgtagacatt
     3181 atctgtttcc ataaaggcaa ggagtttttc ttcctgctct ggtgttagga taacctttgc
     3241 ttccgtatca tcttccagaa catcactcaa cttgaaattg aaaggatttt ttctgataca
     3301 gtcgtcttgt atcgccatat agaatgaagc ctttaaggaa cgcttatagt tatctatcgt
     3361 tttgtaggaa taacctttgt cattcattct gatagcccat tctttagcgt cggactgctt
     3421 gaccgtatca atcgccctca tacccaatgg gtcattttcc agtgcgttca taagatactg
     3481 tcgtcctatt tttgtgtttc tcttgatgtt ctttctttga ttgttcttct tttcgtaaag
     3541 ctggcagact gtcattttac cacccactgt gtcgataccg tcgtcaaggt ctttttttat
     3601 ctgcttttct ttttccctca acgatatatc atcacgtttt ccagcaggtg ttttgtctgt
     3661 gggtacaagt ttccaagcat atacaaactg tggcttcccg aatatatcgg tatatttata
     3721 aacgtatctt ccgtcttttc tctggctctc tccaagacgc aaattgcgtc ctttactgtc
     3781 ttgtcttttc acttttgaca tggtgtaaag ctcctttccg tcatggaatg agccgtgata
     3841 cgctactaat attataccat atctacggct ctaagacatc agatttcgtc cagtgtatca
     3901 ataatttttt caaactgttt tcgttttatc tgaatacggt ttccattgac gataacccag
     3961 ccagagtcca gattttcctc ggcaagccta cgcaacttct tttccccgat acgaaaatat
     4021 cgggacgctt cttctatact aagggtatat ttttcccaga taggcacatc agtattgttc
     4081 atgttgcaac actcctttct gtatgtctta tcataagcag acagacggct tcggaaagct
     4141 ccgttagtat ctcaactatt cccattcttg tgggcagaac cgcaccatgc ggacgtatca
     4201 ttattctgtg atagcaggtc atggcaaagc gaccattcca caagttgctc tcggatcact
     4261 gcgtgggtcg ctcactttct tgtcggaaag gtcatggcgt acagtccccg tggctcgctg
     4321 tatcacaaac gtatctgtct gctttattca gttgtcaaag aacaatcggc gaaagccgta
     4381 ggcttccatg tataaaagca ggagcagggc aggaaagagg gggatttaac caatcacgcc
     4441 ctgctggtat ctgcttattc ttcttcggtt tctatatcta tatcaatctc aaagtctaaa
     4501 atcattttga ttaaggcttc tcgaatacgt ccctttaatt ccatatcaac aacaatataa
     4561 acattgccgt attcatcata taaaggacgt aaacaacact ttgatatgta cgggtcatag
     4621 aataccagta atttctcaat cgcagtttca tccccgtcca tagctgatga aatcaaataa
     4681 taagacgggt gcttgtactt tttcttcatt tctatttctt ctcctttagt atctctttca
     4741 tagtttctag ggcacggtgt ctgtgtttga acacagcccc tctggtataa ttcataatat
     4801 ctgcaatctc tgtatcactc atttccaaga agtaatacat caatacattg ttacgttttt
     4861 tttcgggtag ctgtttgaga gcttctgcaa gttcatcatc aaggacttta atatctatgc
     4921 cacacacatt aaaaattgtg tagtttgttt cgtagtcgtc ccatgttgcc agactttcta
     4981 ccgtaatgtc tggtaattcg ctaaaagata tttccttgtt ttttcttcgt tttaattctt
     5041 tacggtagtt ccagataata cctttgacaa cttttttcag cttacattca aactgacact
     5101 gaattgtttt ttggaagtca gacggtttca taatctcacc tcctttccag ctatgaattg
     5161 aaaagtgttt atccctcttt ccgcaccata tctgtacagc aaggtgtgat ttgcttccaa
     5221 aaaaatgaaa ataattaaaa aaacttttcg ggtattaaaa aagcccgcac aaaatataaa
     5281 ttttgtacga gctactggta tagcgtattt aattgtaaat agtatgctgt taaattgggc
     5341 ttgaatatac tgaattgtac ataaagcgtt tcatacggca agcccccttt acaacattta
     5401 aaccttaacc tttgtctttt tggtaatcgt ataaatatat tcctctggtg ttgggcgctt
     5461 atttccaaag tatcgtttaa aatttgcctg cacgtctggg tctgtacttt ccatagtttt
     5521 gtctatggta tcttgtagca tagccctaaa ttcagataca gaaacacctt gagctttagc
     5581 accaactttc ataatataat tcatatttcg tcttttaagt cctatcatta gaaccaactc
     5641 cctaaaataa gttaatcttc tttttcaaaa attaaatcta tctttcgtat acagcctttt
     5701 gcgtcaattt ctgtgggtac aaaccctgcg tagtgatacc ccgtttttgc gtaactgtca
     5761 ataatttctt tgtgtttatc agtacaaagg aatacaactc ctttcgcatt atagttaatt
     5821 tctacatact catatttttt catttttcaa aactcctttc aaatacaaat ttatctttgg
     5881 atttattgac ttttacaaac tggaattatt cttctatttt caaatcatta ccctcaaaaa
     5941 taaaattatt gatgtcaatc ggtaaacata ttagaacgca aattatagtg tttggttcta
     6001 aagaatttat tttttttgta gaattatagc aataaaattc agataatctc caccgccagc
     6061 ttctattgcc ttacggtcat ttattgcata ttcattattt tgctttatcc aatccgacca
     6121 aacttccgaa ttactttcca tttcatatat tgaaattaaa tctgcctttt tacaatgact
     6181 aattatgtta gaccaatatg ttatatcatg tatataatca agttcttctg gtgtccatga
     6241 taacaataac tcttctggaa gtttctcatg gcaatctttc ttcatgccag gaactgtgat
     6301 ataaacaaac ccacctttct taacaaatgg aagcaatttt tcatctaaat atatagggtc
     6361 acgtccaaaa taattatatg aatctgtact tactacagca tcaaaaaact ctttctcaaa
     6421 tttaagttca ttggcgtcag cttttacaga tttaatttgt gcagaagata atcccatttt
     6481 tttgaaaaat tcttcatttt cttttggctc actccataag tcaactgcaa aaacaacaaa
     6541 tccatattct tttgcaagaa atacagaagt taaaccttgt ccacttccaa ggtcacagac
     6601 atagctgcca gacgggattt tatgattttg taatagttcc tcttgtaatt ttataggatt
     6661 cggtcccata atttttgtct gtaagtcggg tgtaaaatat tttttactgc gaatatattc
     6721 cattttctca tctccattat tgtaatattt taatagttaa tatttgtgac ttataacaat
     6781 attcattttg agttcctctg ctgaaattaa aaagttatgt ttgcattcag gacagaataa
     6841 aggattattt tactttttca attgtaatat atttcttgac aaattgatta acatgtgtgg
     6901 ttaattgaga ttttaaatcc caacaatttt caactgcgtc tgctacactt atcaatagaa
     6961 ataatggcgc ataatattca atagcaagct gttttgtatc acactcttga agaacacctt
     7021 ttttaatcat ttcattaaat atatcttcta tataactgat aggaccattt acaagacatt
     7081 tttgataaag cacattcatt tttaaatttc tatattgctc tagtattaac attttgcgaa
     7141 aattagacgc aaattcatca gtcacccaaa aatcgtattg tgcaagagta aatgttatta
     7201 gacttccaat agttgtattt ctgtatgcat taggggttac ctctattgtg ctttctggta
     7261 cttgataatc cttagctcgc ttattatcaa tttgatacat acgttctacg atacagtcaa
     7321 aaatatcttg cttattttta taatgtttat ataatgctcc ttttgtcatt cccaaggctt
     7381 ccgcaatcat actaacagaa acagcctcat aaccattcac tgcaaataag tgtagtgcaa
     7441 tttttaatat attttctttt gtgtcagaca tttacaacct ccttctttag taaacgaacg
     7501 tttacttctt taaaccatta tagtaaacgt tcgtttactt gtcaagtagt ataaaatgta
     7561 gtgtgccttt ggttcatagg ttgatttctc aattgctggt gttttgtgcc ttgcaccata
     7621 tttcctacat acatttctct atgcaaaaga ctgttgattg taaagaattg tactcaaagc
     7681 tttccttaac gttagccccc ttaaagcact ttctagtatc taaaaacatc attctacaac
     7741 ataacagatt tcaataaacc ttaatacatc ttgtcgtcct cgctatcttt tgaacgattg
     7801 ttagaatttc tcctttggtt atacttcttc ataattacaa ttttaagtaa gccaacgaca
     7861 atcaaaacca caacaatgat aatccaccag tattgttcca taacctactt cccccctttc
     7921 cctttcaata gtcttaaatc atcttccctg tcctatgcag aatagagaag ttcattcgta
     7981 ttaacatgta ccatacaatg tttacattgt ggaaagttgt tttcaatcgt ttgatggact
     8041 ccctcagcaa ttctatgagc gtcataaaga gctaaattac catcagctaa tatttcaata
     8101 tctacataca ttttcgctcc aaacatgcgg gtttttaatt catcaatacc atcaacccct
     8161 tgctgctgaa gcacaacttc cctaatcctt gtttcagtag cattgtcaca actatggtct
     8221 accattttgt taatgctttc tttgaaaatg ttcaaagcag cttttaagat acaaccgcaa
     8281 atcacaacgc ttgcaatagg atcgagaata gcatagccta aacgcgctcc taaaatgcca
     8341 attaaggaac caaccgacga gagtgcatca gagcggtggt gccatgcgtc agccataagt
     8401 gcgtcagaat ttgtatgctt tgcagcactt cttgtaaacc agtacatcca ctcttttata
     8461 acaatagata agactgctgc cgtaagtgcg attccactag ggacagaaag cgtattgtac
     8521 tgtcctgaaa agattttctt gatacctgaa tatcctattc cagcacccgt tatagccaat
     8581 gcaacagaga gaataatgga agccacacat tccatacgtt catgcccata aggatgttct
     8641 ctatcaggct gtttttctga tattttaatt ccaaccatca caacgattgt gcttactaca
     8701 tcagaagccg aatgtacagc gtccgacagc atggcacttg actttcctat atatccggca
     8761 gcaaatttaa gtagcgataa actcagattg atgattagtg taattttgga aacctgaata
     8821 gccttattca tatttttgtt ttgcagaagt ctaccttttt ccataatatg cctccttatc
     8881 ctgccagctt ccgaaacaga cgttttgtaa ggaagtagta ccagactaaa gctaccacca
     8941 atcctataga gaaataaaga accgcctcat tctgcatggc tttcgctacc caaaatgatg
     9001 gaaggaagcc aaccgcgaac tggtagtaac tatcaatgaa aaagggggtt ggtattccga
     9061 gcaatgtaag tgcagctagt tttgtaactg ccataccctc taatttattg cttgataatg
     9121 tgataatcat aagtgaaaca ataattgcct gtactgagcc gagaagcgcc aaacatattg
     9181 tcattccaat ggacaacttt tctaatgaaa aaagtaacag tacaataaaa gcgatgaccg
     9241 ccgaaataat tgagggtact cccaaccttg taaagagata ccccgactta ccaagagggg
     9301 taatcgaaaa gtaccgtgac actttatcgt cgatttcctc caatgtaatc attgcaaatg
     9361 caaagcagag caatacagga gccatgatag aaagtaataa atcaaaaatc ggataatacg
     9421 cttgtaaaga aaacttcgtt attctttcaa gaaatggaat accaaactta attaaagtcc
     9481 ccataataaa aggggagaag caagccgcaa acatcatagg gtcacttttg atttgcttaa
     9541 atatctgtat ggtgctggat aatatctttt tcatagcttt acacctccca aacttttcca
     9601 catatgctca actgtatgtc gagcaactat gtagaggata atcaacgtag caattacaag
     9661 taccatatca aacgatagta aaacgctttt tccagttata aggttcatgc aagctgtgaa
     9721 tggaaaaaag cggaacagat atggtaactt cacaaacaga ccaacaatag gtggtacaaa
     9781 gcaaacaatt tctatcggca taatcacaat gagaaattgg ttcaagtttg aaatttttgt
     9841 agctgcaata attccaagca tagtaaagat tgctgaggtc aaagccgtac caactgcgat
     9901 acccagtaaa tgattgctgc cggaaactac ccctaatatc aatgcgatta ccgtagaaat
     9961 agcaatcaac gcaactgttt ttgaaagtat atattccgat atttttacag gggataccac
    10021 catagcattt aatacctttt gacttttttc caaaagaaca atcgctccca tgaaaaacaa
    10081 tcccattgct gctgggtcag agtagatcat aatagaagca atatccgttt tccaatgttc
    10141 cggcaaagcg gcaatcccgc acacatataa aactgttaat ataaagtaga taaaatagaa
    10201 accatatttc cattggaaat gtatatcacc acaaattaaa cgtcccaatc tcattgaagt
    10261 gtcctccctg taatatcaac aaaaatatca tttaatgtag gctcactact atgaatagaa
    10321 agcaaacggt tttcggaaat taaacttttt aacaacttat cttctgtggt tctatcaagc
    10381 agacattctc cggttttctc gcctttatca tagtaggtat attgtatttt ggcagctccc
    10441 cttgacataa tcaaattatg cgggctatcc aatgcactga cttttccggc aacgataaag
    10501 gctacttggt cacatagctc tgttgcgtca aacatattgt gagtagtaat gataatcgtt
    10561 tttccgcgtt tcttttccgc aagaataata tctttcatta aacgactatt tgtagggtca
    10621 agaccgcttg taggttcatc aaggaataat atatcagggt catggactaa cgctttaatg
    10681 aaattcaagc gagaacgcat acctttggaa aagtcagcaa cttttttgtc cccgtcattt
    10741 tccaagccta ccatatgcaa taattcatca atagaccgag gttgcttttc atatagagaa
    10801 gcaaaatagg cgagattttg tcgtgctgtg aatttctcgt agcaggttga aaattcaaag
    10861 tctaccccaa tattttcata aaactgattt gtatgctccc ttatttctgt acctgcaact
    10921 tttacgctgc ctttatatct tgtattaagc ccagttaaaa ctttttgaat agttgatttt
    10981 ccagcaccag agggtcctaa aaaaccaaaa atttctcctc tcccaacatg gaaacttaca
    11041 ttctccacaa acggtttgtc agtatagcta aaatacagtt tttttacatc aatcattatt
    11101 cattcctcct ttaactttat gacgtttata gatatatagt catataaact gtaaaaaatt
    11161 tgtttggcta cctgcctgtc aaataaccaa acaaaattgt tactctgcta ctacttgctg
    11221 aataatacca ttcactaaaa gattttgtat catattcagt tcttcgtcct ctttgaattg
    11281 ttccaaacag gataaaacag aatacaggga ttttataata accgtatgcg gaaccaaaaa
    11341 tacaacacct aaatcttcca atatctccaa tatacgaata tcactgtaca tatgattttc
    11401 aaaaatatct gacgatattt ttctttgcag atagtccatt aaagataaat caatctgtga
    11461 aagaataggc gaagtaatca cccccgttaa acttagcatg ataacgtcct ttgctaaatc
    11521 tctatggttc ttatactttt tctttttaat ggttgtttct atacttgtaa ataactcttt
    11581 ttgtaagcga aaattgattt caacatatag atgttcttta ctgggataaa aagcatagaa
    11641 agaacctttt gatatgttta cagcagctgc taaatcatca actgttactt tttttaagcc
    11701 gtgtaatgca aacagctttt ctccctctat caaaagttta ctgtttatga tttctttttc
    11761 ttgttccgta aatcgtggca aactcataac ctccttatga ctaaaatatt tatatcgtca
    11821 tgaaaagtat aacatttact gattatataa tcaatatgct atccaagata tttatgcaag
    11881 gtagcttcca atgcgtttat tgtagtgtcc gtgtcctcat taaaaatcat gtgacgatta
    11941 agctctaaag caagtaattc cttttgcggt acatgaatta aatcaaatac tttgttggta
    12001 taatcaaagc taaaaagcgg gtcgcctttg gcagtaatta aaataacagg acattgtata
    12061 gccccattct ccaggcacga taagtcagca ttaaataagc tggcgacaaa tcttaaagga
    12121 taatagggta aaagcatagg gtcatttaag caatcttgtt ttgcctgttc actataaaat
    12181 actctgtcat agtctaaata agcgtctcct ggaaccttgt agttaggcag caattttcca
    12241 cctacacgaa agccccactg tatcagcccc ataaaacggt gcgaccatgt gggatatttt
    12301 gttaagctca tagtttcttt taatgtagtc agcatgatat tatgtggaaa aacggctttt
    12361 aaccttgtgt ccctacctgc cgccattgca gctaaaatcc cgccttgact ggaacccatg
    12421 acagctatgt tttcaccgaa agtttctatt ccgtaagttg ttgcgtcata tacattatgc
    12481 agcaaatctt ccattgtata attttttttg attttagggc tttttccgtg tgaaagatag
    12541 tgaatgccta ttatattaaa tcctctttca ctcaaaccac atagaaaatt ctcatacatg
    12601 agagggtgtg acatagtacc cggcaaaaaa acaatggtag gactacttct ttctgtatac
    12661 cagatagaaa gtgttatcgg aacattattt gaagaaatac caacttcttt atacatacta
    12721 cacacctcct atatgactaa tttggtttta tagtcatatt ataacttatt gcaagcagaa
    12781 agtcaatatc cataaatata tgatttaaga taaatttgtc aagaaagatt taattgctta
    12841 aaatacaatg aaatagcttg tcagtgcagt acatttgcta cagaaaaggc agactatatc
    12901 cgaaaataga tcctgccaac aaaatgtctt acataataat tttccagtta ctatccttat
    12961 gtagaataag ctcatactgc aatacctgcg tcgcctttgt ctgattatca aggaatttta
    13021 cagctacctt gactttcata ttatccccgt cctttgtaag tactgggttt accaattctg
    13081 aataaaggta gtccctgccg ataggttcaa gcacatttcc aaatacataa taggcaagct
    13141 cttttgctgt ggctgtcggg tacagcttaa agaatgtttc cagaaatgcg gtagcgtcat
    13201 tcacggtatc agcgtctaca cttgcgtctg cttctggtgt ctttggctca tagtccgatt
    13261 tttcgattgc tggtgcaagg gtagggttct gaataattac catatccctg tcagcgtcta
    13321 catggacttt taccgtatag gttgccttga ctgttgttgt ctgttctccc tcttttatct
    13381 gctgatctac ttcgtaggta gcagaaaaag tgtccgttcc cgactgttcg atattccaca
    13441 caattacatc tgtaactgtg gggctagtca gtatatcggt tctaatagta tcaacattca
    13501 agtcctgcaa tttctttgtt agataaccgc tgattgcctg catggtacat ctgattattt
    13561 cccacataga taccgacgtg cgttacatac gaaccagcgt tataggttga atggaaaaag
    13621 accaactccc cagcttttgc ctgcgataaa gggatatgct gggttgcgtc atactgtgtt
    13681 tgtgccgttc tcggtaagta gataccagct tttccatagc accattgcac aagtccgcta
    13741 caatcaaagg aagtgttggg attgcttccc ccaaacacat atttccaccc ttgatacttc
    13801 aacgcttcat tcattacctt ttgtgccagt tcccccgaca cctgcggaac agttaaatac
    13861 tgattgacta attccacata aaacatattt ccatagccat accgccagcc cccgttcttt
    13921 gcaacggcta tcgggttggc gtaggttact ttctttccac ccgatttctc acgggcgaag
    13981 ctctctgcaa gattaaaagt gtgctttttc ccttttcctg ccacatagcc cacataaccc
    14041 ccgccatagt tgtaagattg tatcgctaca ttcaaatcgt cgataccttg atttttacag
    14101 gaagaaagca gggacgcaaa atacttacac ccctgcttga ttgagctttc cgtgtctaag
    14161 gaattaggcg gtagtcccag actttctgaa ctctgcatga catcttctgc cgtaccacca
    14221 ctttctactt gagtggcatc tgcaaatatc acagaagtaa aactatcggg tggaaaacat
    14281 acactttttt cttaataaga taactcttaa aaagttgaat tgtggataac tcaaatataa
    14341 gaaaagccca gacgagagtc cgggactttg tctacagcct gaggtacctt atttttaagg
    14401 tacccttatc gttttatttt tataatatac tctctgacga atccaaattc ctattaaatg
    14461 aaaaaagccc gcacaaaaca tatagtttgt acgagccttt aaagctgtat tgcattcaat
    14521 ttttagtaaa gctttattag attgtatttg attgtgtgga attgtactta aatctttcca
    14581 taacgcaagc cccctaaagt actttcttaa gtatctaaaa atctcatttc ccataattat
    14641 ataggttact tgtctcaacg ataatacctt gagattacgt atgtgaaaaa tatttttatt
    14701 acggttttac acattttatg gcataacgaa tttcaataag ccttaataca tcttgatata
    14761 cattattttt agattttaag tctatcataa gccacctttg tccatttccc tctctagtgt
    14821 tacgataaat ttcctgtaca tattcagaaa gcctaggtaa caagttttca acatcttctt
    14881 tctctttatt acctacaacc accaatacag taaagtagtt cttcttcgga tagacaacac
    14941 acaatgattt cccagatttt ttaaacttta cgttccaacc tcgtgcccag acatctttac
    15001 tgtattcgat tttgcaaact gctttatatt cattgttcat atgctgatac aactcatcaa
    15061 atgcagagtt ttcaatataa acgcttattt cactaatatt aggtacataa tttatatctt
    15121 ttatgtttat cacaacggac tatgccctcc tttataagct ttctatttcc tttttattac
    15181 gtcagataat tcctatttag catttactgt ttccacagga attacccata tttccatata
    15241 actaatctct gcatttcctt tgtaatattt ttctgccatg aatggctttg taaccaattt
    15301 atgatttgga agccaagttt caaacagata cttatttgct tgatttaaag cagtggtaac
    15361 aagttcttca aaagattctg cctcaatttt gcatacaata tactcacctg ctggtaatgt
    15421 atgttgtacc atatttttag aacatacatc tgttgatgaa accatacctc ctgcaaagta
    15481 aaggaatgtt cctttatctg gacttgctaa gtgagataca ccaagttcaa tatcattgtt
    15541 aaaaatagca ttttcggttt gcagtttctt tgcatggaat tcgcgccata gctgacctgg
    15601 aacatcaatt cctgtacttt ctccagcagg aatttgttca gcaatattta ctgttttttc
    15661 aaaaccaaaa tatgtttcct ttgttcttaa tgtttttctt tgaatttcca aaacaatatt
    15721 tcctacaatc aatgggacat tttcatcaat catgatataa cgtgaagaaa gttctggctt
    15781 gtcaaatgta tttaacatag gaacattctt tctgtattca tcgggagtaa tatggtaaac
    15841 ttctttaaat gctcttgtga agttagcatg gtctgaaaat ccatatttta aagctatgtc
    15901 taatattctt tcctctgaat tattcaattc tgctattacc attgctaaac gacgaagttt
    15961 gatatactct tgaactgatt tcttaactaa ccttttaaac aagcgttggt aataaaatgt
    16021 agaaagacag gcaatttccg ccagtttctc tgtttcgatt ttctcactta aatgttgttc
    16081 aatatagttt aatgacattt caatattttc atatgcgtac atatcagtac ctccttgtat
    16141 aatttataat caaagtatac atgaaaattt tttgtatagc ttgtcgcaca atgccattat
    16201 cttataagaa atcaaaagat ataaaaaacc aattttgtct atatggtaac ttttattcct
    16261 ttggtacttt ttaatgagcc atatctaata aattcatcac atatctttta attcttttcg
    16321 tatcatagac ctttggaact gtattgtcca ttgcttcgtc aatcgttgct tcaatattag
    16381 ccataacatc aactaatgat atagtcagat ttcaaaatcc catatagata atagtcgcaa
    16441 taggtattta ccattttccc ctcacgaata tgtccttccc tttgaaaacc cactttttct
    16501 aatgttttat aagaagcatg atttaaaata tgcacatctg tccatatttt ttgtaattct
    16561 gtttttgaaa aacaaaattc aattacgcct ttcaacactt cactcattag tccattacct
    16621 tgatattgct tagaaagtct gaaagccact tttgccattc tatcattttc aataaggtat
    16681 atccacagtt cgccaatcac tttgctatct tgtttatgga caattcccca atgaaaactt
    16741 ttagtagctt tctctggctt attaaaaagt aattctggat ttttttcgct ttttgaagga
    16801 cgtttccccc aatactcgta taaagaaata tcactaatcc attctttcaa atcatctatg
    16861 tcatttttat tcattgttct taaaataaga tgttctgttt caattactgg tttttcaaaa
    16921 atgtaatcct gcaaactcat ggttcatcac tccttaaaaa ttaaattcgt tttcccatgc
    16981 aaaagaagca gattcttcta agctgtgagg ccaatgacta caccaatctg gaacttgcgg
    17041 attttccact ctatccaaac tcggcgtgta tggtttaata tccaagatag gcgttttgtc
    17101 attagcgtca atataagcaa tttgtatcag cccactcata taatcaatat tgataatttc
    17161 tactgctgat aaagcaatcg gatttgggcg taccggcgac cttgttgcaa aaatccccat
    17221 tttctctgga gcttttttat aaggttggtc tgtttccaat acgcttctaa aatccgcatt
    17281 gtcaaaattg ctgaaccacc acaaaacatt gatatgactg aatccgtcta attcctttaa
    17341 tgctagaata tatggcgctt ctagttgaat gaaagcacct ttttcattgt tgtagatagt
    17401 acctattgaa tttactttat aagttgtcat tatattttcc tccgttttct tcttgataaa
    17461 taaacgataa accttaacac catgttaaag tcaaggcaga ttatcatttt ttacaagaga
    17521 ttttctaaag gaatttggat ttctgttaga tagttctctg gatttttctc gttccacggt
    17581 ccacgatgaa ctatttgacg gcttgaacct ttcatcttat attgactgtt ttcttgaagc
    17641 cattttgcaa atgaacgata agcataagaa atattagaaa aatctccata taccatagta
    17701 caagccatca tagaaactgc ttcggtaaaa cgaaacttaa aatctcctgt agcttttcct
    17761 attttattta caatggcaca taattctaca tcaacatctt tttctttata ttcttcattg
    17821 tgatatattg agaatgtttc atcagaaata tttattttat tttctttagc aaaagcagag
    17881 agttctttcc agagttcgcc ctcataataa taatttggta tttcttttct taaagataaa
    17941 acgcaataac tcggtatctc ttttatggtt atgttaaaat acaattcact tttgccatgc
    18001 aacaattctt ttttagcaat ctcaattttc tttagttttt cttgttcttt ttgtatatta
    18061 tccataattt caatagactt tttatcaagc tgttctataa tggtatcatt actgcaatcg
    18121 agggctaatg caatttcagc gacattgaaa ccactatcac gtaaatatat aattctattt
    18181 aaagttgaga tttgttctgc tgaatacata cgatatccag ttaatgaatc aactttagca
    18241 ggttttaata aacctgtttc atcataataa cgcaacatac gagtagaaac ttgtgtcaat
    18301 tttgaaaact caccaatttt gaacatttta tccctccatt catgtaccta attataatta
    18361 ttgttaattt atacttcaat ataaaaaggg cttgcatagc ataattatga tacaagccca
    18421 tttccatgtt atcctacaat tttccagtta ctatccttat gtaacacaag ctcatactgc
    18481 gatacctgcg tcgcctttgt ctgattatca aggaacttca cagcaacctt gactttcaca
    18541 ttgtccccgt cctttgtaaa tactggattt accaattcag aatacaggta gtccctgccg
    18601 ataggttcaa gcacatttcc cgatacatag taggcaagtt ctttttctgt ggctgtcgga
    18661 tataacttaa agaatgtttc caaaaatgcg gttgcgtcat tgacagtatc agcgtccacg
    18721 cttgcgtctg tttctggtgt ctttggctca tagtccgatt tttcaactgc tggtgcaagg
    18781 gtagggttct gcacaattac catatccccg tctgcgtcta catggacttt tacaatataa
    18841 gttgctttga ctgctgttgc ctgttctccc tcttttatct gctgatctac ttcgtaggta
    18901 gcagaaaaag tgtccgttcc caactgctcg atactccata caattacatc agtaacggca
    18961 gagctggtcg gtatgtcggt tctaatggta tcaacattca agtcctgcaa ttcctttgtc
    19021 agataatcgc tgattgcctg cgtccttgct tcaatcgctt ctttgctgtt attccatgtg
    19081 taataggact tcgcaaagtt cttcacgaaa ttttcaatcc cgttggtatc agtaagtctt
    19141 aattgtatgg tttctgtttc atgtacggtg tgcatatcaa tagcggtaaa attcttatac
    19201 acgccaaaac tcacgcttgc gataagcacc acccacaatg caatcacagt tttcttatgt
    19261 gtacccactt tcacggtacg cactttcttt tctttgacat tttctgtcgg tttcttattc
    19321 ttcttaaaca tattttcaag tcctttctat tgttttactc gtcctgcacc aattaagtgc
    19381 tgtttccagt aactactatt taagtctgca tatcctatcg ggtcgcctgc atggtacatc
    19441 tgattatttc ctacatatat tcccacatgg gtaacatacg aaccagcatt ataggttgaa
    19501 tggaaaaata ccaaatcccc agcctttgcc tgcgaaagtg gaagatgttg ggttgcgtca
    19561 tattgcgtct gtgccgttct cggtaaagag ataccagctt ttccaaagca ccattgtgtt
    19621 agtcccgaac aatcaaagga agtgttggga ttgctaccgc catatacata tttccagcct
    19681 tgatatttca atgcttcact cattaccttt tgtgctagtt ctcccgatac ctgcggaaca
    19741 gttaaatact gattgactaa ttccacatag aacatatttc catagccata ccgccagccc
    19801 ccattcttcg caacggctat cgggttggtg taggttactt tctttccacc cgatttttca
    19861 cgggcgaagc tctctgcaag gttaaaggta tgtttctttc cttttcctgc cacatatccc
    19921 acatagccac cgccatagtt gtaggactgt atcgccacat tcaagtcgtt tattccttga
    19981 tttttgcagg aagaaagcag ggacgcaaaa tacttacacc cctgcttgat tgaactttct
    20041 gtatctaaag agttgggcgg taaacccaga ctttcgctgg actgcatgac atcttctgcc
    20101 gtaccgccac tttctacttg aatgatagcc agtagcacat tgacatactc ggagataccg
    20161 ttttctctgg cgtatttttc caccataggc tgatgtttca agacttctgc ggataagttc
    20221 atgcccgtaa tgcccgaaga aaagttgctg ttctcgtcat cgctgtcagc actaatcaac
    20281 accccaaaga acagcaccac agaaaagagg ataggaaaca gactgccaat gatagcgata
    20341 tgtttcaatt tcattttttc ttctgtcctt tctttgttac aaggttacgg ttcttttcag
    20401 tatgttccgt tgtatgcttt gcttgttcaa aggtctgtgc ttttgtggta cgttctgctt
    20461 tgtaattctg gcgtgtttcc tgcgatacca ctttttctac atttttccta tgtactggct
    20521 gtgccgattg tggagttttt ccgtcagaag ctcccgaaga taaaggacgt tctttcacac
    20581 tatttgtttt gactggctcg cctgctttgg aagttgaagt tatagcagga cgtttgactt
    20641 catgcgtttt ctctacactc agctttgaag ctgtggctgg tcgttcatgg ggacgggtag
    20701 ctcccgttgt cgctgatccg tccgtctttc gtgcctgcct tgcttcttgt gccttttgaa
    20761 gttccatacg tttgtcagcg atagttttct tatgctgttc ctgcttttcc aaacgtcccg
    20821 actgtctgga ttgttgttcc tgcaccatgc cacgcttgaa gtccgatacg cttgtttttg
    20881 ctttttcctt tgcagaatga acggcataag cggtctgtgt cggcatatcc ttgaccattt
    20941 ctttcatggc gttcgccttg tctttcactt tattcttcgt atctaagact gcacccagct
    21001 ttgagcctgc acgctgtccc atgctggaag atgtattccc tcggttttct tttgctgaat
    21061 tattccttgt tgtccttgca ttagaaaccg tactgccagc caccgcacca gcaacaccgc
    21121 cagcggtaac agcaccagca agccgtcttt ccatacgcct agccctatgt gccatataga
    21181 gatacggtct gcggaaaatt cttcgtccca tgctttgact gtcgttagcg ttcaaagaga
    21241 acatactcat taagtcgccc agcttcatgt agataccagc gaaacatact atctgcaaga
    21301 acgccaccat aaagaacggg tagtctgtgg aaatgttata aaacatactg gaaatactga
    21361 acgccaccgt tacaatgagc gtaattcctg cccttgtcat tatggtatta aataccctca
    21421 cgattgcctg cttcgccatg ctttcatagc tcggtatcat ggatagtaaa aagctgatag
    21481 gcagaaacat ggcaaagatg ataaaaagta tctggctgaa caacatcata cccgtaagca
    21541 agaatacaaa tatcgtgata cccaagttga agaacaagag gaagaacacc atacctaaac
    21601 ggtttacgac ttgcggtatt gtcagattat tattgtcgtt gttttcgatt tctgttttca
    21661 caacttcctc tctggtcttt ccgtcctcgt cctctgggct tgccgataca agagcttcta
    21721 cacggtctgt tccgatttcc tctgcgttgc tgttcccaaa ctgtaagagt agccacggct
    21781 gttccacttg aatagagaat aggctgtccc ttatcaagtc cacgctgtcc ttgccctcgc
    21841 tgtcagagtt tgggagcatg atttttgttc ccaagtccaa agaagcggta ctaatatcgc
    21901 ttgaaaactc atttatcttc ttgatgtaat cgggtgcata ggcaataaat gaagccgata
    21961 aaatgaacac cacaacaaag ttgataacgg cgtgaagtgc cttgctggtt tctcgtttaa
    22021 tcagtcccgt atatgctaca taaattccca ccaccaagat aatgagaagc aggaaaccaa
    22081 catagaagcc agaagttgaa aaaccgcttg aggtaacgcc tgccaaggtc tgtatgctct
    22141 gtccgatact gtctgccata tcattgatga agtccagctt ataggcttcc tgcactacat
    22201 aacctgtggc attgcttaaa taaaggctta tcatccagac aaaattagtg atacagtaaa
    22261 gcccatactg tactgatttt ccgataccgt ccagccagtt ccacggcaac caagcccagc
    22321 tattatccac ataaaaatca agctggtaat tcgacagagg atattttgaa taaagatttt
    22381 ctgcgtttat cgtatcgtct acaagccccg ttgcatgagc caccgtccca agtagtgaaa
    22441 gcaggataag ggaaagtgcc acggcaaaca gcgttatttt aagaaagcgg aacatcttct
    22501 tttttgtgaa cgcactctgt atcctttctt tcatcactcc acctcatttc tctgtatggg
    22561 cggtctggta tcaaaggcgt gtagcagttc ttcaaagact gggtgtatct gtaccacacc
    22621 gacacgtccg tataagtcct gcaataaaca ttgtccgttc tccaaatcac gaagcctttt
    22681 ctggttgttt tcgtcctctt tgtcgatacc gaaaaattct aaggtctgtt taatctcgtt
    22741 gatgtcagta gaacggaaag cgaattttaa gccgatattg tttttcagac tttcctttga
    22801 cacgtcccca gaagattgcg taacgaaata aacgcctgcc tgcatagctc gtccagcacg
    22861 aaccagcttg ttagataaag tttcgccttg tgccacattc aagaacgccc acgcttcgtc
    22921 aaggtctacg attttgaaga tagagcggtc gctgtggata aaatctaagg caaaggtact
    22981 aatcacaatc agcatggaaa ccgatagtaa ttcaatggtc gtgtattcct caaaagtcgt
    23041 gtctttatct ggcagtacaa ggtcggctac ttgaatgata ttgagctggt tatccaaact
    23101 gatagcattt tcaaccgttc cgtctgaaaa cagaagatgt gcaaagtcat agtccgtaaa
    23161 gctgtcgata tggtctgcga tattgcgtga gattgcggta tcttcacagc gtaactcgtc
    23221 tatcacatga agcaagcccc ttgtttcact ctgggtaaca gaacgcaccg ccttacgaag
    23281 tacggggaat ttttcgccgt ccctagagga aataccagtt aaaaaggtta gtatgtcgat
    23341 tgccagactt tcagcgtctt tcacattctt cataatcaca aacgggtcaa gaagccctgc
    23401 gttgtccttg tcgcttgtta ggtttacgat attgatttca tgggcgattt ctggaagtgt
    23461 ttctttccag tttccacgct ctgattttgg gtctaagata accgcttgac cgccaaacaa
    23521 aacagaatag tacacaagca ggttattaca gaatgacttc ccaccgccaa gcgaaccaac
    23581 aaaagcagaa gcaagggcat ttgtaactgt accttttacg ccttgactgg caagggacgg
    23641 ttgcagatat acatttcttc ccgtatcaac ggaatagccc atatagatac ccgtgttttc
    23701 ccctaactgc tgtgtcgcac caaaaccaag cccagctaag aagtctgatt ttacatactg
    23761 cacataatca ttgatatatc gcttgctggc tggtagaaat tcagaatgaa gccccagcat
    23821 atccccagca ggacgtacta acttcacatt caaatcgtca taaaaatctt tgacttcatc
    23881 acaacggcgt ttcagttcgt ccaaatcatc agcagacaca cggataacat aagagagctt
    23941 atacatactt tcttttgtct ggtctaaatc ggtttccagc tcgtccacgc tgtctaaagc
    24001 gtctactaca tttgagctgg tttcacttcc agcttgataa gcgtgattat caaggtcttt
    24061 cagttccttt ttcttgttgc ggacggtcgt taatgctttt cggttttcca cgatttctac
    24121 attcatgctc gtatcaacgg gaaaggtaaa ttgctgttgc tggaaataga agatttcact
    24181 agacggaaaa tcaagctcgc ctacaatcgc attgacggta aaataggata cataactttc
    24241 cttgtcctca tgttccaatc gtaaatatcg ctggctttcc tcaaccacac accttgtcgg
    24301 gcggataagg tcgtagtatt ttatcagcgt ttcctttttc aatttcttct ttggtagctg
    24361 atactcataa tcttcatagg cgataccgtc cctgccgtaa agatgttccg tgagatagcc
    24421 aaagtcattg atttccagac ggcgaacctt gaaacgcctt gatattttat tttccagtaa
    24481 cttttccatt ttcatgtaac ggttgatttc atcattcggc atggaaacaa agtcgttcat
    24541 tagcgtgtgg ttcacttcat ggagaaattc tttgaacgtc agccacgccg atttttttag
    24601 gttcttcaga ttgagctgtt cttccgtaac catgagcttg aagccaagaa aaaagcggta
    24661 gtctacttga ttgtccccaa tcattgatac taacgcttcg gtctgttcgt ctatcttctg
    24721 gtaagcgact tcctttaatt ttccagttac caatcttttt gactgttcct gcatacttcg
    24781 gattgagctt tccgtggcaa tctgcagcgc atggatttta ccctcacggg actgtgcaat
    24841 tagctgtcga aagctgtcat gcacgataaa tttctgctct gcggataaga aagaatagtt
    24901 gtacggtatc agctcatagt aggcgaatac ctcattgtcc ttgttccaga caaggttatt
    24961 atcaatatat ttaatcggga acatagttca cactccttac tgccgtgatt gtttcgttga
    25021 atatttcctt ttgcagtttt acggcttttc ctgcataagt gattttaggt cgcaacgcat
    25081 aggttatctg tgacttcaaa aagctgtacg gcttctttcc gtcaaaagtt ttctgtgaca
    25141 tgaaccaagt gaggaaagca ggaataccga agtattttaa aaatgctccc tcaatcatgg
    25201 aaagtggggg catatcccca aacagaatga tgataaattc cgtaatcaca aaccatgtaa
    25261 tctgtgtaaa ggtaacggga aagggcaagt taaagtcatt gattgcatat aagacttttt
    25321 ctacattcca gatacccgtg tagcttctaa tctttttcaa gttctttcaa ctcctttcaa
    25381 aatggaaaag gacagccata tttcagactg tcccttaaag aaaaatacgc cgtcagtagc
    25441 aacaatgctt gtcgctgatc ttccagcgtt aatatggtat ctcgcacata cctcggcttg
    25501 tttcaatgaa gtaaccgccc atatccaaat ctcgcccaaa tgcttcatag tcaatgtagt
    25561 tctgcaagtt agggggaatg tccccaagtg cctgcaattc gtctatgtaa aaataggcaa
    25621 catctgtcat ggtttcacaa tcgggataat agtaaatatc gtccttgtgt tccacgactt
    25681 cttccagcgt cccgtaatga ccaataaatt cgtccagaca atccacgata tagtcgggaa
    25741 gttcctctat catttcatac atctcattga gttcttcaat ggaaacatac tccccaatct
    25801 caatagggaa gttatcggta tcatggattg cgtattcttc atactgttca ttcaagccga
    25861 ttttttcttt tacatcttcc tcgtcaatag ggaaagtgaa ccaagcaccg actaaatagc
    25921 cctcattgta cttgccaaga ttagcgatat aaaccgccat atcatcaatc ataagcacca
    25981 cctcatttct tactctggca attcaaagat accgtgttcc gttactaaaa atttcccgtg
    26041 ttcctgcaag tgtaaagaaa aggcttcaaa gtcaaaatag tattcttgac agtcctcgga
    26101 taaatgtttg aatgtcgggt cattcatcag tttttgtctt gccacatcaa tcatgctttt
    26161 acagtcggga taaatagtaa tcacgttcct gcaaatataa agtgcttcta aattttcaaa
    26221 cacggtatga agtgccgtat attcttcctg tatatcactt gaaagctggc ggtacatata
    26281 atctaattcg ttgagctggt aaacggttgt atgctcatgg acttcatcag caaagggcag
    26341 taccttttca ataatacggt actccccact ttccgcaccg acacctaact tttcttcaaa
    26401 ctctgcaacc tctatcggca ggtcgaacca gtatgacgtt gtttcttcgc cagttgttcc
    26461 gctcgtttcc accagcaccc ttgtttcctg cattgttctt cacgtccttt ctgttgtttc
    26521 atcacatctt ttaaggtctg gcatgacata ccaaacacat agttagaaaa atcttctaac
    26581 tgtttttctt catagtcggc aaggttcagt tgcttcattt catgccacac tttacgcttg
    26641 taagagggta ggtctgaaat gttttcacag ccaacctttg cctgtatatc tctaaaaata
    26701 tcgttcatta catcactcca atctgaattt tgagtataga aaaagcagtc aatcctaaga
    26761 ctaactgctt tgtgtatatc tgatattaga ttatgaaatt gagtttatca attcttgtac
    26821 ttcattaaaa aatctggata aatgaaaacc atctgcaacg gcatgatgta tattcattgt
    26881 aagaggcatt atatatcttt ctcgctctaa ttcatattta ccccaagtaa tgactggtgc
    26941 aagaaatttt ccttcgtcaa aaacatgaac atcaaaatga ttgtatttta cccacggcaa
    27001 acaagataca tcaaaaaagt tcaaaggttg atttgctacg aatgcacgtt ccattttatg
    27061 tttctctcta tctaacataa atcgtgcgtg aaattcaaat atgctatcag aaaaatctgt
    27121 aaccgttttt gtgaaattct catcttcttt atgaaattca gtataggacg gggaaatata
    27181 gtcccattta attagattac ctttattatc ccaactatat ttaaactcat catgttcatt
    27241 aacgaccttt gaaacaaccc atatcatagc tggataaaat ttcaaatcat ggctctttga
    27301 aaatttaatt agatttgtta catcaatatc tacggttaag ctcataacga tacgcatatc
    27361 atcaatgtaa ctttgaaaca atttacctct attccatttt tctaaatcaa tttttgtata
    27421 tttatattcc atgtccattc tcctttacat tttgaaattt agtaaaatgc aaggctctct
    27481 ggataacatt tcactccatg caagtctatt ccattaagcc ttgtatggag ataatacaat
    27541 acacaatttc ataatatccc tccttatcca ataaacctta gtttattgtt ttcatactca
    27601 gattatacca ttctcatatc agcactacaa taaaatttta cgcaccgata atcttattga
    27661 acagctctaa cagtacatct ttcacaccgc cagcattgaa caccaagccg acagcaatca
    27721 aggcaactac caagaagccg ataagttttg aaaactcacg cttgaaccct aagtagatac
    27781 cgataactac aatcgccata agcactaagc tctgggcgtt acttaaaaac catgtgtata
    27841 aattttgtcc gaaattcatt taattgtcct cactttcttt taatttcttc atttcatagt
    27901 cagcttcttt gccgacagtc aaaatacaca tcaagactac gccgataccc attccaaatg
    27961 ataccagcag gaagtctttc aataattccc acattttttc atcactcctt tgttttggca
    28021 accatttctt caactgtggc tgtctgttgc ttgattatct ggtagtgtcg cacggtcagc
    28081 tttgcctgct tttcaatcgt ttccagatac tccgtttgat tgtccttgtc tatctgcttc
    28141 aacatcttca aggtcggtgc aacctgcctt tgtagccagt tgagtgtacg ctccagcgtg
    28201 taaggttctg gctttgttgt cagttttatg ggcgagcgac cctcgccaat gaaccaagcc
    28261 cagcgtacat tggttttcca gtcgcttttt cgcttgtctg gttctttatc agcgaagcgg
    28321 atatattggt tgataataga aaatgctgtc agttctgcgt cataatgtgt cagcagttcc
    28381 acaacagcat aataggcacg ttcatttttc aaacgtatct caaatctatt ttttatgggg
    28441 acttcttcaa tcggtatgcc gagtttggcg tactgttcgt aattcttttc ataacagcag
    28501 aagtacactt cacttgaaaa tgagccgata tacagcgtgt gtcccatacc gtatttatcc
    28561 gtttcattat gctttaccaa ttcgccagaa ccatagcttt tgaaagaacg gaatttagaa
    28621 atacattcct cattctcaca ttttcgtatc agctctggaa tgtcaagtaa gcccgttcgg
    28681 tcattgattg ccaaatcaag acgcttcatc acaccgccct caaccaatgc gtccgtgaag
    28741 aagtcatacc agcttcgttc ttgtgccagc agatagcttt caaactggcg acagcctttg
    28801 cctttcagtt ccagcaggac acctttttct tcgtcctgcg atacatacac aaacacatct
    28861 ccgatatggt aatgctcggt gtatttgtaa tgtccgtaat cttcgtgaag catatagtcg
    28921 atattgagct ttaatatatt cttgatgata tgctttatat ccattgtggg aaaacggata
    28981 cgcacataat caaacagcag gaacatggga ttgtcgggat tgaatttttc caccgcttct
    29041 aaaagcgtat gtttcatgtc ctcagtcagc gttacctttc ctgcttcgat acggctcaaa
    29101 tgttcacggc tgatatttgc catgattgca agccttgtct gcgatacgct gtatgcacag
    29161 cgtttctctt tcaaggcggt taaaaaatca gtttcattca gttgtcatac ccccaatcgt
    29221 gataattttg tgatattgtg ataatttcaa ggttttatca caaaaggcga aatgtacgaa
    29281 aaaccctcat tccatgcggt cttgcaaggg tttttgtgga agtttccgcc gtaattgtgc
    29341 ccctctgtta gataatgagg ggcttgtatc tgctggcgtg gctaacgcca caccagcaac
    29401 ggctagtccg tgccgtcgcc tttcgcttcg cacgtcgccg tcccgtcctg ccttgcgtat
    29461 gcaagtgagc ctatggtctg caaaaaatca tgtccttttg gaactaaggg tgtgtaaaat
    29521 tcacttatga cgcttgttcc cacatcacaa tagccacgtc ccttgatacg cttctggaaa
    29581 aactgctttt tcacatcaga accgaacagc ataccgtaac ctaattcgct gatacgcccc
    29641 aagccaacac ggaaattaaa attatctctg ataccgtccg agaaatattt tgcgtctgga
    29701 cgctggcagg caacaataag gaaatatcct gcttgtcgtc ctaacatgac gattttcttt
    29761 agctggctaa gtaggctcac actttctttt gtccccagca tttcaaaaaa cgccacatat
    29821 tcatcaaaga taagaaagca gggcggtaaa ccaagatagg catagttttc gcccgtttta
    29881 tagtctgggt gtcgcttcat ttcttcgctt ctttgtacca tgccctcata aaaggcattg
    29941 acacaatcaa tcatttcttc tttggtgtga tacacatttc ccatgaccgt acctaaatct
    30001 gcaaggtcag cgttcttcgg gtctaatatg taaagaacag cgttcgtatg taacagagct
    30061 tcaataagcg tcagcagaaa atacgtttta ccgccaccag tcccaccagc aatcagagcg
    30121 tgagggagtg cgtcatattc ccatacaaga tttttcatca gcctaagaca gccgttttct
    30181 gctttcactt catcaatggt aatgcggttc gctatcatgt cataaagcat ggtgtattcg
    30241 atataaccgt catgtaacgt cttgtcggtc agctcacaat acaagccact ttccaattta
    30301 tcctctaacc gtaagagctg gtcttgatat tttcctaatg taatttcaca gcggatatga
    30361 agcagtcctt tttccatttg ataataaatc tttggaaacc agatgatttt ttcccttgat
    30421 ctgctttgca ggtcagtaaa aaaaccgctg tcttgtacgg tgtctgcttc ataccacttg
    30481 ttttccagta tcattcgtgc cagcttttga cggtgcagga gcttcttgaa actgtcataa
    30541 cagaagcggt aatacagaaa agcgaccaat gcacaaacac cagtcgctat cagtagggtt
    30601 atgaagttgt aagtggaaag cgtcaaaccg ttgtctaata agctgaaatg ctcccaatcg
    30661 gtacgcatga gctgtttcat attcagtagc aggataaccg caatgaatac aaacagaagc
    30721 gtccctatgg aaaagtggta gacaaggttc ttgtcgctgg ctctgatacg gtgtcctttg
    30781 tttaaaatca ttttcataaa tcaatcactc ctttctgggt acgaaaaaag cagtcaatcc
    30841 taagactaac tgctttgtgt gtatggatat gaagttgtca aactgggatt tattgttctt
    30901 aacttttctg tcgttataaa gctgacttac gcacattaac ctctgcacag accagcccag
    30961 ctatatgctc cgctgtttca tttgtcagta caaagagcat tccgtcatta cggcattttt
    31021 tatgtgtgtc gccattcaag gcataaacaa aacctttcac acaggtatca ctacaggcat
    31081 tagggtcaat cagtctcttg cagtcacgag aagtagtcat tttcttttgc atatcagcag
    31141 gaagcgaagc gattatatcc tcatactttc cagcgttgtc tccgtaaatc cgtgcaaaaa
    31201 cacctgtctt gcgaaacacc caattcatta ctgttttctt ctctagttgg tatgaagcgg
    31261 tgtaaccgct ttttgcttcc tttattacaa ggtcacagcc ctgctcaata agtttggtat
    31321 taagtttctc gacaaacgct tggtgttctg gcgcgattgc cgatagaaat tctttgaatg
    31381 aacctttttc ttttgccatt atctttttcc tccacaaatt tcaatttatc cgtttcttca
    31441 tacacatatt ataacagttg cttatatccg ctacaatgaa aatctagttt gccagcttat
    31501 ttctttggtt gcccctgcgg tgcatggttc tgtggattgc ctacttgacc gcctttattc
    31561 ttcaagataa tatcgtcagc cttgatatac cagtccacat tgacacctcg atagctggcg
    31621 tttgctaccg tatcggctac gggattgaca agctctacct ctgcattata tggatagtct
    31681 ttgacgggaa tatcagcagg aattgatact tgtatcatgc gttcctgcac actacatttc
    31741 aaatcatagg ttcttcgtgt gatttcttca cttgttgaac cgtcgtcatt ttctgctcgc
    31801 acctcatgtc tgagggcaga gaacttcaat acaccgaaag ttttttcctt gtctaataca
    31861 ataccgtttg ctaatctcat aatcatttcc ccccttactt gctttcctcg gctggcaaca
    31921 tatcatcagc cgttaagata tagtttgtga accctcgtcc tttgaccgct ttaccgtctg
    31981 cggtaatctt tggattgata agttttactc gctgttctgg tttgaaatgc ttttcgcctg
    32041 ctttcgctgg aatggttacg ataatatcat cagccctttg tacgtcagag tacaagttgt
    32101 agcttcttga tacgggcgta aagcgtccgt taatgcgttg ctgttcaatc ttgttttcgc
    32161 cagcaaattc caagtttcca aaagtctgtg ccatgttcgg cactacatat tttaattcca
    32221 tagtgtttta cctcgtttct ttcttctttt ttaagtttgt tgattgtact ttcttattct
    32281 ggcaattagg gaaataccag caatccccca gatagtaaag ggtaaatcaa tgcttcgcac
    32341 ccttgactat ccgtgtgctt gtaggttgtt ggcagacaag ccagaataag taaacgtctg
    32401 ccgtttgaca gcttcggcgg agagcgtgat ttttcttttc tcataccgtt accgccttat
    32461 gatttcttca ttttacggcg tttgtaaaga tatgttccag ccagtccacc agcagatgta
    32521 agcaacatta ccagaaatgc catgacattt gtgttgtcgc ccgttttagg actgtctgtt
    32581 ggtctgctcg gtttttctgg tgttgttggc gtttcgggtt tctctgggac ttctggtttt
    32641 tccttaaaag taatcgtctg tccctcgtcc tcaatgtcct tatgctcagt aacttttttc
    32701 ggctcgtttg gattgcttaa atcatacaat tcttcaaaag ttacaagctg tttgccgtca
    32761 agagaagtag cgtcaaaggt aaaggtaact tccactttca tagtttcgct gtcagcgata
    32821 aacgtataat cactttccac acgttttcca ttgataagaa gctctgcatt ttcttctttc
    32881 aacatctgcc agcccacaag tttatacttt gtaccaactt ccaagccctc taaggttaca
    32941 gtatcaatga ttgttacgtc ttttcctgct tcaagctctt tgttaccgtc cttatcggta
    33001 gcagttgtat gtattttgat gatacgttct gtaataagta ccgtctgccc gtcgtcctca
    33061 atatctttat gctccgcaac tttcacgggt tcgtctggat tgcttaagtc gtataattcc
    33121 tcgaatgtta ccagattttt accgccaagc tcggacgcat tgaatgtata agaaatttcc
    33181 actttcattt cttcatcatc agcaacaaag gtataatcgc tttctacacg tttcccgtca
    33241 atgataatct cggcgttttc ttcctttaac atctgccagc cttttaactg atacttagtg
    33301 ccttttgtaa gtccgtctaa tttgacagta tcaacgattg ttacctcttt tcctgcaagg
    33361 attgtctttt cgccgtcttt gctggttgct gtggtatgga tagtgatttc cttttcgtat
    33421 tcatcagtca aagtccctaa atcaatcaca agattatttc ttgataccac gatttcaaat
    33481 ggtgggataa gttccatgcc tttgttgctg tcagagcgta attcttcaat aatgtaagta
    33541 tcgtaaggca acgcaccttt gctgtcgtct ggttcagaag ttccaaacca tacaccgtcc
    33601 tcgcttgttt tgccagcgtt ggtattgtgc ttgtgcgaag cccattttga agaagtggag
    33661 aattgcccat tatcgtcagt taccacaaca tgactttcgc ccgttgtctt gcttgtgatc
    33721 ctaaagggaa catcagcaag acgcttgtgt gtgcctgcac cgattttcac gccctcaata
    33781 tcgccacgct taatctgatt gtagatagag tgggcttcgt ctgttaagtc cacgattttt
    33841 ccgttttctg tgattgtaaa atcaatcgtc ttcgcaccgt ctgtcaagta accgtttgga
    33901 gcttgtttct caacgatacg gaaattcccg taaggcaaaa ggtcagcaga agtagaagcg
    33961 ataccctcaa tatccgtatg gattgttttt acaacttcgt ttttcttgta tatcttgccc
    34021 tcaaccaata ccgcattatc atttaaggaa atgatgtcaa aggcagtatc tttcaaagtg
    34081 gcacttcctt gtggtttggt atctttggtt tctaaatctc gtttctgaat tttgacaccg
    34141 ccacgaatga cttcatctga tacggaaaac tggttacttc cagttaatac ggcaaggtcg
    34201 ccgtcctcgg taatctgcgt aaggtataag gcttttatct gttcttcact accattcgcc
    34261 tgcatatatg caccgtctaa taagtagccc gttggcgatt tcgtttcttc gaccgttagt
    34321 gtaccaagag gtaaaaccgc ttttccgtcc tgcatataga agctatcgcc agataccttg
    34381 tatgcgtctg ctaattttgt gatgtaatgg gttgtcccgt tactgtctgt ttcagcggtt
    34441 gtctttgtaa cccatgtacg agtagcttcg gcaggaagat tgtctttatt gtagaagcct
    34501 gcataatatt tccatgtaaa ctccgccccc tctaaagaag cgttcccttg tgggttgctt
    34561 ttctgtgttt ccatgtcaat tttaaaaagc tcaatcaaag tatcggtaac ttttggcgta
    34621 tcagatactt tcaaagtcgc tgtctttcca gcttcgactt ttaaggaata caccgtagta
    34681 tcaactttat accccaatgg tgcagataat tctttgatat atacggtagt agctttgact
    34741 tctgcaacct ctgtatttcc gctgtcgtca gtcgtaaggg tagcaatctg tttggtgcaa
    34801 tccttatcgg aaaagacacc gtaagtcgca ccagcgatag agtaatttcc gttaccgtta
    34861 gtaatgctgg tattattaga agtcttttga agtttggcat ttccgacatt taacttcgcc
    34921 cagaattgcc ctaattcctg cccctcgcca gagtagatat aaccgccgca ttcatagcgt
    34981 cctttgtttt ctttcacaaa ggcttttgca ccagcaaaca cttcatcttg tgttgccttt
    35041 ggtatttcat cataagaagc tcgcacgtta tcacattgcc agcctaagtg aacactcaat
    35101 ctttgccaga caacaagctg tcttaaaagg taggcgtgat tattgcttat cccattgtgg
    35161 ctggcggtgt attgcttcac atattcgata gataaagcaa catcacttat ctggtcggca
    35221 ctcatacggg agcttgcgtc agctctggtc ttatagccgt tcttaaaatc tgtgttaatg
    35281 tcaatacagt aagcgtcctc gccttcaacg gtcaaatgcc cctcgttaaa ggtagaacca
    35341 atcgaaccgt cattcattac cttttcaacg ataccaacac gttcttcact ttccgtccag
    35401 tattgcttac tttctgcatg aacaagtgta gtcggtaaag cagtaacgac agtcgcaaag
    35461 gcaagtacgc ccatacacaa tcgtttcaat atctttttca taattctaaa tgctcctttc
    35521 attttgggta ataaaatagc cgttcaataa gaacggctgg aaatagaaaa ggaacgtcat
    35581 tttaggcgtt ccatagtcta tgaaatattc aatttttttc ttgcttcaat actgatgtgc
    35641 cgtaccatat ctttgcatat ctaggaaaac tagcgtatca aggctcattc attggtagta
    35701 aattagtagt aaattgatgt gtttgttttc ttgaaaatgc tgatagatac tgtgttttag
    35761 cggataatca actttttagt atgttttttt atataaacta gcatataaaa tatattttct
    35821 tcaaaataat attttttact gaaaattgaa actatgcaat cattttttat actatacata
    35881 tagataaatg attatattta ttcaatattc ttataaaaaa caaagttctc catcgaaaat
    35941 tatggcataa taattgctta ttatattaat aaaacaataa aaagcaattg gaggaataaa
    36001 aatgcaacag gctttgaaat taaaatatca aaccaaagaa ttaggaaaag attttgtaat
    36061 agaaagttgt aattctataa aaccatggct tataaacata agaagagaat tacataaaat
    36121 tccagaatta gctcttgaag aaaatcttac taaacagaag gtaatttctt atttaaaaga
    36181 aatcggaatt gattatatgg aatttacaaa acacaatgga attatggcat atattttaaa
    36241 agaaagtgca gataaaacga tttgtataag agcagatatg gatgctcttc ctattgaaga
    36301 agaaaacaac ataccttata aatcaataca ttctggaaaa atgcatgctt gtggtcacga
    36361 tgcacataca accatgctac ttggagcatg taaagtttta cattcaataa aagataaact
    36421 taatgtaaat gtaaaattct tatttcaacc agcagaagaa ggttttggag gagcaaaatt
    36481 tttagttgag gatgggtgtt tagaaaaccc caaggccgat tatatattcg gacttcatgt
    36541 tatgccacat atagaaacag gccttatcga aacaaaatat gatacattaa atgctagtgt
    36601 agacactata aaaataagta tcaaaggtaa aagagctcat ggtgcatatc ctgaaaacgg
    36661 tattgatgca atagttacag cttcacaaat tgttacatca ttacaaacta taataagtag
    36721 aaacttagaa ccaaataatg ctgctgtttt gactataggt aaaatatatg gtggtgatgc
    36781 acacaatgta atatgtgaag atgtaaaatt agaaggcact ttaagaacct taaatagcaa
    36841 aacaagaaac tttatgattg ataaaatagc taaaattgtt ggagatactg catctgcatt
    36901 tggttgtgtt gggactttac atataagtga tgaaaactat cctgctgtta taaatgaaaa
    36961 agaattagta gatacagtta tatcaagtac taaagaatta cttggagagg aaaaatttat
    37021 attgagacca aacccgtctt taggtggtga agacttttct ttttatacag aacattgtaa
    37081 aggagcattc ttccatttag gatgtaaaaa tgagaaaaag ggcttaattt cacctcttca
    37141 tacctctagc tttaatatag atgaagattg tttaccaata ggtgttatga tgcatgtaat
    37201 gaatactttg tattttaatt agtacagtaa ttaataaaag aataggagat aaattaatat
    37261 ggaaaaagct aagaaattag gtctatttag tatgatatta ttagggatta atagcataat
    37321 aggttcaggt atattcttac taccaggtaa agtttataat ctagcaggtc aaaacagtat
    37381 gtttatatac atttttgcta cactcttagt tctatcaata cttttatgtt ttgcagaagt
    37441 tggaagcatg tttgataaga atggaggagc atatctatac tccaaaaaag cttttggaga
    37501 ttttatagga tttgaagttg gtacaatgtc ttgggttatt agaattatat catggtctac
    37561 tctagcagta ggatttgcaa cagctttagg ttcattttgg ccagaatctg ccactgaata
    37621 caaaggttat atagctgcaa tactcgtaac actactttca ataaatagct tatttggaat
    37681 taaaagcaca aagataatga ataatgtaat aactatagct aaattagtac cattaatagt
    37741 ttttataata gttggaatat tctttataaa atttgtaaat attgttcctt caggaaatgt
    37801 agttaactct agtatgggtc cagccattat attagtattt tacgcattta ccggctttga
    37861 atcatttatt gtggcaagtg gagaaatgga aaatcctaaa aaaaatcttc cagtcgcatt
    37921 aataaccaca atatttatat gtgcaataat ttatatatta attcaaattg tctgtatggg
    37981 tatacttgga gatagactat ttgaaaacag tattccaatt gcagatgctt caagtgtatt
    38041 tttaggcaat tatggtaaag ttttcatatc tgtagcaaca ttaatatcta tatttggtat
    38101 aaatataggt tcatcaatag taactcctaa atgtggttct tctctagcag aagaaggttc
    38161 tcttcctgca tttataggaa aaacaaataa atatggtgct ccatatgtag caataataat
    38221 atctttaatt tgttgtatac cacttgtgct aactggaagt tttgaacaac ttgcagtaat
    38281 gagtgtaatt gcaagatttg ctcagtacat accaacttgt ttatcagtaa tagttttaag
    38341 aaaaagaaca gatgttaagg cctcttttaa gattccattt ggtcctgtta taccaatggt
    38401 agctatttta ggtagcttat ggttgttaca acaagcttgg gcagaagata tttcaaaacc
    38461 tataactcaa aatagagttt taataggatt aggggcaatg ttgttaatag ctcctctata
    38521 tatatttatg aaaaaaaata aggaaatcga gcataaaaat aaatcagaag attctaaatt
    38581 atatatttcg agagaaaaaa ttcaataata ttttacaaac tatttaaaaa ttatttttct
    38641 aatactatag aaataattag aaatggagat gttacgtatc taaaagtagt tgataacacg
    38701 gatattggta cttttataga tatgggactt acaaaagaca tactagttcc ttttaaagct
    38761 aagacttatc cattgtttag agatgaaaaa tatttattct atatatactt ggataaaagc
    38821 ggaagaatag ctgctactac agacatagat tcatatttag aaacagacca tacttacaat
    38881 gtaggagatg ttgtaaatgg agttgtatat ggattccaaa ccaacaactc tgctatgata
    38941 tgtgttgaca ataaatatgc tggtgtaatc cttcataatg aatactttac agaattaaaa
    39001 gctggggatg ttcttgaaaa tttacatgtt ataaaaatat acgatgatgg taaattagga
    39061 ctttctccta gaggaaacag aaaagatgaa cttgatacct tagaaaataa gattttaagc
    39121 tatttagaag gttcagatgg atatatgaga ttcaatgata aatctgatcc taaagatatt
    39181 tctatcttat ttaattcaag taagaaaatt ttaaacgtgc tcttggagta cttatgaaga
    39241 aagacttaat ttatcaagat gaagatggaa cttatctaaa gtaaattata taacacaaaa
    39301 atcgaagtaa attatgaaag atattttcta tttcatattt acttcgattt tttatttaaa
    39361 ttactacctc tatttaaatt actacttata tttattgtgc atttactacc tctattatgt
    39421 ctaattcaca aatcttttta atgggttttc ttactgcaag caaagttatt attatcatag
    39481 ttactacaat gataaacagt aaatcaaaag gtatttgcca gtctatatgg aattttaatg
    39541 ttactaagga tacaaatata tatctatgta atattaatcc aagtacactc cccaataaac
    39601 agccacttac agcatatgta cttgattcta ctattaccat ttttcttaat tgcttattgg
    39661 acatgcctat tgcacgcata ataccatagt aatttattct acttgtaacg cttatattca
    39721 tactgtttat gatattaaac atacttataa tcgcaattat aaatacaaac ccatatacaa
    39781 aaactgccat agtgtaaaat gaatttttag cctctaagtt accttgtcgc ttatctcgaa
    39841 cctctaaatt atcatctaga acatttctta tattttggat taaatcttca ggagcatctt
    39901 catcaacttg agtatcaatt attatatagt cttttatatc tgttatacta gtaaaagtat
    39961 tttcagatgt tataatattt ccaatatatt tgtctttaac atcaaatgaa attgaagaaa
    40021 gtatacctgc tacctctatc tctttcttag aatttccatt tttaatatat atcttatctc
    40081 caatattaaa cccatgacct tcttctacca atccgatatt ttctgactct aatttatctt
    40141 cattgatttc cccttttact agatactttt tggcccagtc aaattgattt ttttcataag
    40201 aaattagctg agatgttgcc tccttattat tgtatgtagc ctctacatcc gtcatcattc
    40261 tactgtatac tttttttatt cctttgatat tacttatttc attaatatcg tctttagtaa
    40321 gaacagactt aaagtcagcg tcaacaatag atatatgagc agcttctggt tttataggtt
    40381 taagtgcctg atacataaag tctataaata cactaaaacc taaaaacaat acaatactaa
    40441 tagcaaatga agaagtcata agtataaaag atttttttct tgaaaaggca tgatttattc
    40501 ccatagaaac atcaatttta gaacttcctg cgttagcaat tttacttgct tttccactag
    40561 ttaaaatttc tttgaacatt agattaccac gtatagcact tagtggagac accccagaag
    40621 ctttttttgc tggaacaata gctgataata ttactgttaa aaatcctact attattccaa
    40681 acacaatacc aataaagcta acctttaaaa ttggcatcga accaaataac tctgtattca
    40741 catatttgag aaatatagag gatataatgg ttacaataca tcctaataac aatcctagtg
    40801 gaatagcctt tacacttaga attaaacttt ctaaaacaac aaattttttg acttggagtt
    40861 ttgatgctcc caagcaacgt aatagtccaa aaaactttat tctctctatt acacccatat
    40921 taaagctatt atatatcatg ataatacttg ctattaacac aagtataaaa agtcctcctg
    40981 ctgttaagta aagtggttta gaataatcag agtcaccttg acctataata gaaagtaatt
    41041 tttcattttt accgatttgt ttatcactta aattgaaggt attcttaata tcagaagtag
    41101 cttttctaat attaaccttg tctttaaatg taatataata ataatcatat gtttctgatt
    41161 ttttgatagc ttgtgtacct aatattgaaa gcattaatcc atgcttatct gaggctctta
    41221 agcttgataa tgatgaatat tcacctacta tcttataatt tttatttcta ccatctgcta
    41281 attttatttt gataaaatct cctactttta gattaaagct tttaactgca tctacatcta
    41341 ttaaagtctc attctccaca acaggataac gaccttttat tatttctaga cctaattgtt
    41401 ttgctaaatc ttcatctaaa ccttgtatca aaatctcctt tgatttaaac tctccattat
    41461 caatgacttg tcctctacca tagtgagcta tatctactct actacttatt tctgatatag
    41521 cttcttcatt aagattttta agtactatgt gccaatttcc atcatctttt ataaattgta
    41581 ctttttgaca ttgtatagcc atgtctgcta gtccaaaaat agcagtaact aaacatactg
    41641 caatgacaat acataaaatt gtagttctat tttttttctt atgtaccttt gcatattgtg
    41701 gtactagttc taaatagctt ctcattctct attcacccct aggtctttaa gcattccatc
    41761 agaaacctgt agtatcctat ctgctgtaga agctatattt gtattatgag ttatcataat
    41821 aatagtttgg ttatattttt ctgctgtcac ttttaaaagt gaaattacat cactgctatt
    41881 tttactgtca agatttcctg ttggctcatc tgccaatata attgatggct ttgtaatcaa
    41941 tgctcttcca attgcaaccc tttgttgctg accaccagat aattgatttg gaagatgact
    42001 ttttctatct ttaagaccta aaattgtcaa tacttcatct agataaatag tgtctggttt
    42061 tttgtaatct agtagtaaag gaaatattat attttgttcc acagttaatt cgggtataag
    42121 attatatgat tgaaagataa aacctatatt acgacgtcga aaaatagtct gtttttcttc
    42181 tttcattgaa catatttctt taccatcaac aaatattttt cctgaggttg gagtatcaag
    42241 acctcctaaa agatttaata atgtactctt acctgagcca gattctccaa ctacagtaac
    42301 aaactctccc tttgaaactg taaatgatac atcttttaat gcctctactt ttgtatatcc
    42361 atttccatat gttttacata aattattaac cacaagaata tccatttgct ctatctcctt
    42421 tctgatgatt aatataagaa taattcatac accttactgt aagatgtatc ctatcttaca
    42481 tattagtaag ctttaaaaaa cttagagtaa atgtacttcc ttgtaaaaaa ttactttcta
    42541 cagttatggt tccattgtgc tgttctatga tagatttaac tagtggcaac cctaatccaa
    42601 ggccttgatt actttttgaa aacttactcc tataaaatct tttaaatata tgatgtatat
    42661 cttcaatatg aattccattt ccggtatcac tcactgaaat aatagttgtt ataggtgttt
    42721 caacccattc tatcattatt ttatcgttct cttttgtatt atctaatgca ttttttataa
    42781 ggttgcttaa agcttctgat atccattcat aatcgcaaaa caagtttgta ttttctagac
    42841 ctcttataga gatactcttt ccttcttttt ctgctctagt ttcaaaacta tataaaattt
    42901 tagtaatcaa cttttttacg ttaacactag ctttgttaag aattattgtc tttgaatcta
    42961 tctttgtaat ctttaacaag ttttgtatca atgattctat acgctctaat tcattttgac
    43021 tcttctgcac aaaattctca acaatttcac tattatgact ctcttcctgc aatatttgat
    43081 tatacatcat caatgctgta agtggagttt ttagttgatg tgatatatct gaaattgtat
    43141 ttttaagaaa ttctttattc tgcttttctt tcaatatatg tgtgtttaga gatgttgaca
    43201 tagcatctat tgaaccaaat aactttgata aactaccttc ttcataagta tttaaccgta
    43261 catttatatt tccattcata aatgaatcaa ttttataact agcttcttct atcttgttct
    43321 gttgcctaaa aaaatacaca tacaatataa aaataatcat agtaaagaac acaaataaat
    43381 acaaaaacat agtttttata tatttacctt gaaacaattt cacacttggc ataaaactat
    43441 catctgtacc aaagtcatat ctagctgtat ttaagatttc ttttcctttt aaagtatatt
    43501 tatcttcatt agtagtaaat actgctggta tttttgattt atcaacaccc atactattta
    43561 agtatccagc tatattataa tcatgttcta acagtgcact tttataatca ttagttatat
    43621 ttataactac tatttgacct actactataa acatcaataa aacggatata atcaccaaaa
    43681 aaaatatttt tatgtcttta ttagaaaata ccttcatatt aacaccctca ctttataaca
    43741 ttccatttgt aacccattct tctaactgtt aatagaattt ttggattttc aggattatct
    43801 tcaatcttat ttcttaacct tcttacatat actgacagag tattatcatc tacaaaacta
    43861 ccatttccat cccataactt atccaatata ttttttcttg taagtacaat atttttattt
    43921 ttcataagta agcataataa tttatattct gctgtagtaa gctcaagctc aatttcattt
    43981 ttaaaaacac gattttcaag taatttaaca gtaatattat ttgattttag ttcagttaca
    44041 ttttcacttg taaaattata acgtctaagt aaagctttta ttcttgaaat taactcattt
    44101 aatttaaaag gttttgttat gtaatcatct ccacccatat caagtcccat cactacattt
    44161 acttcttcat cagaagcagt taaaaatatg attggtacat tagaagcttc tcttaccctt
    44221 ttacaaatat caaaaccatc accatcaggt aaggatacat ccaaaagcag taaatcataa
    44281 tttttttctt tataaatttg caatgcttct tctactgttc ttgctacatc aacactaaat
    44341 ccattctttt gtatagaata ttctaatcca tatatcaaac ttaaatcatc ttcaaccaac
    44401 aatatactac tcatctcaat cacttccatt tttttatttt ttactttata tatattatat
    44461 acctaactta ttatattttt actcttttaa aaatacaata ccttgaaatc aatgatttaa
    44521 atattttaaa attattttta tatgatttta tatagttaat ttaatacttt gaaatcttaa
    44581 taataaaaaa agcttaaaat acactaagta ttctaagctt tattcaatca cattttatat
    44641 atttatatta tttatttttt taaaatacta ttttcaatat tgcctctatt aaacatttca
    44701 ttatcattat ctaaagagat atcacttata tttctaacag ttgttgaata gttaccacta
    44761 agttctatct cactgaaatg catatgcact atcttttgta ttacaaatcc cattgatgca
    44821 agtaaaatag caaatattat atactgacta aagttactca tataataatt tataatggta
    44881 tattcatttc ctttgactgt taaatgtttt gtagatagca tagtatatat atattcagta
    44941 caatttataa atacatatat accataaata gccaacacta cagataaaca atacattgtg
    45001 attgaaatct ttgatatttt tttaaactta ctatctttac aacacttaat atttgttatt
    45061 tatcataaac aaggttattg tattatcaat aatttttagg ttacacttat tattagtctt
    45121 gtgttaaaac gacagtagac ttaagagtag agttttatta agccaatatt tatatttgct
    45181 atacattgta cccctattac atcatacata taacttggat aacttatttt atttttattt
    45241 ctaaattatt taaaatcaat atctacacca ttatcgataa ttgcaattaa attcatataa
    45301 aacctcttta atttataggc tgttcactat aaagtcttta tttcttccat aaaattttca
    45361 ttttgaattt tattcaatgt ttttagtgta gttatcatga ttatagatac taaaataaat
    45421 actattagta taatagcccc tataaatttc caatttatta aattgatact ttcaaaaggt
    45481 tttattatta tacttcttac aattaaaata ggtattatag atatacaaaa gcttactata
    45541 atatatatat aactttccaa tttaacaatt ttatttattt catgttttga tattcctatt
    45601 cctctaaata gtgcaaattc cctacttctg ctattaatac tagtaactat agtattgcaa
    45661 caattaaata aagataatat aactataatt ccagttacta ataccataat tagtgttttt
    45721 tgattatcaa ttttttcata ttcagctgtt tcagctttgt atggaattaa aattccttta
    45781 tttgtttttt ctgttatttt gtttaactca ctttcaacat atttatcatt ggctagttta
    45841 ctcgtccata tgtcaaatct ttcataagat gatattcctg taaacttatt aaattgattt
    45901 gttgatatta ctccgccaaa ttcagctccc acttgtgagg ttactggtaa tgtagttata
    45961 attccacata ctataaattc ttgagatatt gttttggtaa aattatttgt ttttgaatct
    46021 ataatatcaa agtatacttt tattctatct ccttttttta tattaagcga atcactggat
    46081 ttctttgtta tatacagata tggttgttta ctaaatttat ctatattttc ctttccattt
    46141 atcaagaaat cctctagtat atctgtatct tctattccta aaaattcaaa agaattatta
    46201 tataccttaa ttccatcttt tacttctgat ctagcttcaa tattatcttt attttttttc
    46261 caataatcag agttcttatt tatactttta tcatcaattt ttatattaaa ccacttatgc
    46321 ctatatgagt ttacttttgt tacaccatca attgccttta tctcttgtag tacattttta
    46381 tcataacctt tattatttga acgtatagta cttatatcaa tattatgtaa taaataatct
    46441 ccttgtatcc aatattttaa tacaccatca cttaaaaagt tactagtaga ctttgtgtat
    46501 attgttgcca ttaagaaaaa tataattacc attgatgcta tagataaatt tgtacgtttc
    46561 ttatttcttt gtatattttt tgatgctatg ttaccatagt ctttgaaaag ttttatcata
    46621 aatttattta taaaggaatt ttgttttata tccacttttt cattatttct tcttatacaa
    46681 atcattggat cagttttaac tgataacata agaggttttg aaactgatat tattatagtt
    46741 cctaaactta ataatataga aattatgtat gtgtttatat agttctggtt ttttatagaa
    46801 tttatatagt tgacattgta tattactcct ataacatact cccttgataa actagctatt
    46861 atcccaccta aaattagacc tatagaaata cttataatag agtatataga tacttctaaa
    46921 atcattattt taaaaatatc atttggatta aaccctaaag ccctaaatat cccaaaatcc
    46981 tttattctat ttgatactaa tatataaaaa atattataaa ttaataatat agttgctagt
    47041 gctagtacta tattaactat tatataaggt atttttaaat tcatactatc agatatagct
    47101 attaataatt cattattaaa ataaatgtta ttctcattca aatttccatt tttaataagt
    47161 ttttgtgatt gtctctgtat atttttttcc tttttaaaag taaacataat ttgatcatat
    47221 ttatttttag taggaatatt cttgatagca caatcgttac ttataaggcc aattgatgtt
    47281 ccttgagctt ttaaaatagg attactattt aagataccag ttattttaaa ttctttttcc
    47341 ccagtatata aatcttcttg atctatccct tgtcttctat aatctaatgt tatccttttt
    47401 cctatagggt tttttatctt tttttgttta atataccatg aatctatagc gatttcattt
    47461 tcagctactg gtaatttacc tttttctagt gtgtaaatat catttagttc ttcagcaact
    47521 ttatcctgag atagaatttg tagtgtttga cctttaccaa tatcactaat tcctaaaagc
    47581 attgattttc caactttatc tatacttgtg ttattttcta tatattttat ttcttcgtct
    47641 tttggattga tatattgtgc atgttttaat gtaaattcat ttttagcttg atttatcatt
    47701 aagtttgtcg catcttcact tattatattc ataattaaaa acaacgctgt tgaaattaca
    47761 atacttacaa ttattaataa tgtatttttc ttatttccca ttatatattt ttttacaata
    47821 taattaagtt tcataaatct acctactctc ttataaatcc atcttctatt tctataactc
    47881 tatcagcata ttttgttata tctatattat gtgttatcat tattattgtc tgattatatt
    47941 ttttttgaga ttcttttaat aaacttaata catctgactc tgtctttgtg tctaaatttc
    48001 cagtaggttc atcagcaaat acaattgatg gtttatttac aagagccctt gctattgcta
    48061 ctctttgttg ttgcccacct gataattgat ttggcaaata cattcttcta tcttttattc
    48121 ctagtaactc catcaattca ttaatataag cttcatcttt attttttata tttatagttg
    48181 gtagttttat attttcttca acagttaaaa ctggaatcaa attatatgat tgaaatatta
    48241 atcccaactt ttctttacgt aatgcagatc ttttcttttc atcaagagat gatatattta
    48301 tattatcaat aatcacatca ccatttgttg gagtttcaag tcctgccatt atgtgtagta
    48361 aagtactttt cccacttcca cttttaccta ctatcacaac aaattctcca ctatttattt
    48421 ttagatttat ttgacttaac gctttcacct ctgtttccga tttaccatat attttattta
    48481 ggttttttat ctctaaaata ctcataattt actccttgtc ttacatgtta tttacactta
    48541 taaattcgat ttttgctatg gattttgcaa tctctatcta tacttattga tatgtagcaa
    48601 cagaaactat ttttataatt ttcaaaaaat tcttccgcct attcactcca tatagtgcct
    48661 ttagttatca taccatatct tataattgaa ttttatttct tatatctctt ttaccaacct
    48721 ttttatttag gaaaagttct tcaccatgaa attgtacagt atatacctat ttctttgatt
    48781 atataattaa gctttttatt tagtaaccta ttttctacat cctaacttat atttcctgtt
    48841 tcctcatttt catatttata acaatagtta caatctaaat tactactttt agttacccag
    48901 actttacttt acatgctttg cctctaaact gctgatgtta atatcttctt aattttttca
    48961 cacctatctt caaatataaa atctttatct aaaagattat tgtattcagc tagacataac
    49021 caacaaaatg atttcattaa atattcttta cattcattat tacataactt taagttgaaa
    49081 aactcattat atccaaaatt cgttgatacc catattatta atataactta caatgtcttt
    49141 ttgaatatct aaaaaaatac ttttataact tattttatat atcatacact atattattgc
    49201 tttcataatc tataaaggtt tcatatgata caaacttcta agatgggatt tttggtcttt
    49261 aataacgatt ataataatat ttatttatat ttctgattta aacattattt tacttgaaat
    49321 gtttattaaa taaatgaatt aaaactaaac tttcattata tttttaattt attcaattaa
    49381 at
//
LOCUS       DAEPXW010000019        47238 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.019, whole genome shotgun sequence.
ACCESSION   DAEPXW010000019 DAEPXW010000000
VERSION     DAEPXW010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47238
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.019"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            134..880
                     /locus_tag="KRM55_001073"
     CDS             134..880
                     /locus_tag="KRM55_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBH1593326.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            941..1615
                     /locus_tag="KRM55_001074"
     CDS             941..1615
                     /locus_tag="KRM55_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH1593327.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKAEELADWISEYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLKCMMSCPWSL
                     RYANQK"
     gene            1983..3329
                     /locus_tag="KRM55_001075"
     CDS             1983..3329
                     /locus_tag="KRM55_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH1593328.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNIIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIIALTGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDIIVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEKAYSIFYGDILESCNIVLMNRNIDTLESDSLNEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            3356..4756
                     /locus_tag="KRM55_001076"
     CDS             3356..4756
                     /locus_tag="KRM55_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH1593329.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENRAI
                     ITAKSVRHCIKNICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAVICEDKQ
                     GEPGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNEDNWEDFKEDKH
                     KVYLIEALKTKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSNDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            4966..6402
                     /locus_tag="KRM55_001077"
     CDS             4966..6402
                     /locus_tag="KRM55_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH1593330.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIEATYGEKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            6746..7690
                     /locus_tag="KRM55_001078"
     CDS             6746..7690
                     /locus_tag="KRM55_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBH1593331.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLRDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEIFKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEGNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            7859..8791
                     /locus_tag="KRM55_001079"
     CDS             7859..8791
                     /locus_tag="KRM55_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBH1593332.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIVLLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIICLSKSETTSKAK"
     gene            8896..9363
                     /locus_tag="KRM55_001080"
     CDS             8896..9363
                     /locus_tag="KRM55_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBH1593333.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(9607..10461)
                     /locus_tag="KRM55_001081"
     CDS             complement(9607..10461)
                     /locus_tag="KRM55_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBH1593334.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            10627..12591
                     /locus_tag="KRM55_001082"
     CDS             10627..12591
                     /locus_tag="KRM55_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1593335.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAINHITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            12591..13052
                     /locus_tag="KRM55_001083"
     CDS             12591..13052
                     /locus_tag="KRM55_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1593336.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNVDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            13055..13375
                     /locus_tag="KRM55_001084"
     CDS             13055..13375
                     /locus_tag="KRM55_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH1593337.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            13391..14491
                     /locus_tag="KRM55_001085"
     CDS             13391..14491
                     /locus_tag="KRM55_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH1593338.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            14611..17211
                     /locus_tag="KRM55_001086"
     CDS             14611..17211
                     /locus_tag="KRM55_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBH1593339.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKSRENVLEETPAGNIFIEEPGYYILKVR
                     INIQLPALGYKVVSFESSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRKNGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKKLEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
     gene            17680..18015
                     /locus_tag="KRM55_001087"
     CDS             17680..18015
                     /locus_tag="KRM55_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593340.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            18152..19429
                     /locus_tag="KRM55_001088"
     CDS             18152..19429
                     /locus_tag="KRM55_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBH1593341.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIRSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            19550..20938
                     /locus_tag="KRM55_001089"
     CDS             19550..20938
                     /locus_tag="KRM55_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1593342.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            21309..22022
                     /locus_tag="KRM55_001090"
     CDS             21309..22022
                     /locus_tag="KRM55_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBH1593343.1"
                     /translation="MNKISKRGFDDGDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            22140..23009
                     /locus_tag="KRM55_001091"
     CDS             22140..23009
                     /locus_tag="KRM55_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1593344.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(23164..24309)
                     /locus_tag="KRM55_001092"
     CDS             complement(23164..24309)
                     /locus_tag="KRM55_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH1593345.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(24642..25418)
                     /locus_tag="KRM55_001093"
     CDS             complement(24642..25418)
                     /locus_tag="KRM55_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH1593346.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            26000..26974
                     /locus_tag="KRM55_001094"
     CDS             26000..26974
                     /locus_tag="KRM55_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH1593347.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            27072..27377
                     /locus_tag="KRM55_001095"
     CDS             27072..27377
                     /locus_tag="KRM55_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1593348.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAQGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            27532..28692
                     /locus_tag="KRM55_001096"
     CDS             27532..28692
                     /locus_tag="KRM55_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1593349.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            28742..29644
                     /locus_tag="KRM55_001097"
     CDS             28742..29644
                     /locus_tag="KRM55_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH1593350.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            29724..30617
                     /locus_tag="KRM55_001098"
     CDS             29724..30617
                     /locus_tag="KRM55_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBH1593351.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     gene            31323..31796
                     /locus_tag="KRM55_001099"
                     /pseudo
     CDS             31323..31796
                     /locus_tag="KRM55_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014521021.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            31786..32631
                     /locus_tag="KRM55_001100"
     CDS             31786..32631
                     /locus_tag="KRM55_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003485307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593352.1"
                     /translation="MYSKIAIKNVRKSFKDYSIYFLTLTLVICIFYSFNSMESQKALM
                     EMSTSKKPDLEMFKNMISYISVFVSAILCTLILYINNLLIKKRNKKLGIYMTLGMGKI
                     EMSKILVFETIIVGIVSLVSGLILGLLVSQGLLILLLKLFEFNMSEYSFVISIPAIIK
                     TIVYFGIIFLLVMIFNIYLISKYKMIDLLIVERKTEDIKFKNPFVYMITFVSCFIFLF
                     TVYNTTNHIIINLIDDKQLNSKSKGVEINEFTYQDWQQFCDIKYYGKKGLISMTLKEY
                     IEKYN"
     gene            32886..33653
                     /locus_tag="KRM55_001101"
     CDS             32886..33653
                     /locus_tag="KRM55_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014521021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593353.1"
                     /translation="MKNILSVEKIEKYYGNKDNITKAIDNISFKVDEGEFVGIMGPSG
                     SGKTTLLNCISTIDNVTIGKIIINNNDITRLKSKNLDKFRQNELGFIFQDFNLLDTLT
                     AYENIALALTIKGEKPSKIDSKIRDVATYLEIEKVIDKYPYQMSGGQKQRVASARAIV
                     TNPSLILADEPTGALDSKSARLLLERFESLNQDLKATILMVTHDAFTASYAHRILFIK
                     DGKIFTELVRGADSRKEFFNRIIEVTTLIGGDDNDVF"
     gene            33643..35637
                     /locus_tag="KRM55_001102"
     CDS             33643..35637
                     /locus_tag="KRM55_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003400181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593354.1"
                     /translation="MYSKIAIKNVRKSFKDYSIYFLTLTLAICIFYSFNSIESQKALM
                     EMNASTKSHVEMLKNMISYMSVFVSVILCSLILYANNFLVKKRNKELGIYMTLGMEKV
                     KISKILVFETIIVGIVSLVSGLILGLLVSQGLSILLLKLFEFNMSEYNFVISISSIIK
                     TIVYFGIMFLLVMIFNTYIISKYKIIDLLTIGRKTEDIKFKSPFVYTITFILCIISLI
                     IAYSMVLKVGLNPKNPKFIMSIVLGVIGTILFFYSLAGFALYIVKKNKNIYFKGLNIF
                     VVKQINSKINTNFISISIICLMLFLTIGILSTGFGFKSALNAGLKGATPFDASATMIV
                     HEKCKVKNIKESFEKVGIKFNKGDKVAYYDEYINGNKLSDVMQGQYSGRVDFEVAYIK
                     SSQYNEIRKLRGEKSITLSKDEVLITSNATEVVPSIEEYMKNNKIIKIDNKAYNIKNK
                     KVIKDNLRTDFTETNALTVVVNDKLCDSMEISSSIVNINFASDNNEKSQENFDKRLKS
                     KYSSTSFYEVGTVSGGSRNAMYNDNNGMTSTILFVGIYLGIVFLISSMAVLALQQLSE
                     ASDSIDRYVSLKKLGASKNSISKTIFTQTLMYFSIPVGLALVHSVVGIQVANNFISRL
                     NKPDIGASSLMTVGILMLVYAVYFYTTYQGYKNIVIKKLN"
     gene            35714..36385
                     /locus_tag="KRM55_001103"
     CDS             35714..36385
                     /locus_tag="KRM55_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005210744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593355.1"
                     /translation="MEKIIIVEDEEVIRDELKSFLERYGYEVMAPTEFDNIVEFILSE
                     KPNLVLLDINLPIYDGYYICRVLRKESNIPIIIVTSRNTDMDELMSMNLGADDFVTKP
                     YKTQILLARIVALLKRSGLNSNVNNTLIFKGIELNLFNATLRYKDKEIELTKNEFKIL
                     SYLVENQGSIVSRDSFMEYLWHTNWFVDDRTLTVNITRLRKKLDEIGIENLIETRRGL
                     GYIIS"
     gene            36382..37389
                     /locus_tag="KRM55_001104"
     CDS             36382..37389
                     /locus_tag="KRM55_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003358391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1593356.1"
                     /translation="MRLREYIGDKVVFLGTNLIIFLIASGIMLYSKINVVLIFMLFCI
                     WFLPLFTYMLIDYLQYKKYFNSIDNILDALDKKYLLPEVIDDVNFVTGEKINDILKVI
                     SRNMHENIKYYNDNQEEYKEYIETWVHEIKTPIASSKLIIENNSNEITKKIDTQLDKV
                     ENFVEQVLYYSKIDNVNKDYIIKKLNLEEVVNEVIKRNYRDFINKNIKLELGEINKTV
                     YSDSKWVEFILNQIVVNSIKYIKSKDGLIKISAKRVENSIVLTIEDNGVGIEERDINK
                     VFEKGFTGENGRVFGKSTGIGLYLCKKLCNKLGLGLILESKVNVGTVIKVSFPIDYNL
                     F"
     gene            37554..37949
                     /gene="tnpA"
                     /locus_tag="KRM55_001105"
     CDS             37554..37949
                     /gene="tnpA"
                     /locus_tag="KRM55_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBH1593357.1"
                     /translation="MKLDSNNHSVFLLHYHLVMCIKYRRKVIDDSISDRLKDIFVDIA
                     PNYGVVLIEWNHYVDHVHLLFKAKPNTEISKLLNAYKSASSRRIKNEFPSIRKYLWKE
                     YFWSKSYCLVTTGGATLEDLEQYIENQEE"
     gene            38543..39673
                     /locus_tag="KRM55_001106"
     CDS             38543..39673
                     /locus_tag="KRM55_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1593358.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            39745..40770
                     /locus_tag="KRM55_001107"
     CDS             39745..40770
                     /locus_tag="KRM55_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH1593359.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KLIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            40773..41969
                     /locus_tag="KRM55_001108"
     CDS             40773..41969
                     /locus_tag="KRM55_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593360.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDNKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(42097..42822)
                     /locus_tag="KRM55_001109"
     CDS             complement(42097..42822)
                     /locus_tag="KRM55_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1593361.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEYATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSVDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            43300..45399
                     /gene="nrdE"
                     /locus_tag="KRM55_001110"
     CDS             43300..45399
                     /gene="nrdE"
                     /locus_tag="KRM55_001110"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBH1593362.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGNKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            45412..46383
                     /gene="nrdF"
                     /locus_tag="KRM55_001111"
     CDS             45412..46383
                     /gene="nrdF"
                     /locus_tag="KRM55_001111"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBH1593363.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            46459..47085
                     /locus_tag="KRM55_001112"
     CDS             46459..47085
                     /locus_tag="KRM55_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1593364.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLWDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT        18735 a         4909 c         8065 g        15529 t
ORIGIN      
        1 tttttatatt ttgtaatttc aaattaataa ataattagat ttgataaaca aaaaataaaa
       61 atgttgatta tattaataaa ctttaatata atatatttat gaaaaatgta aactgtgaaa
      121 tggaggtagt aacatgaaaa ttgaaaatct ttctattgat gatattaaac gaggctatat
      181 atttaatgat gatttaaatt gttatagttg cattaaatgt acaaaaacat atgaggtagg
      241 agaaatatat aaaataggta atagattctt tgaagcttca aaagctattg aacttcatat
      301 ggaattagaa catagtgatt atttagagca attgcttaat agtgattcaa aatacaacac
      361 attgactgaa aatcaaaaac aattatttca attatttatt agtgatttac cagataagga
      421 gatagcaaaa caggttggag tatccacatc tactatacgc catcaaaaat ttattttcag
      481 agaaaaagca aaacaggcta agctctattt agcactatat gaatctgtat ttgaagataa
      541 atctaataaa agtagtacta taataccaat ccatgaacat gctcgaatgg tagatgaaag
      601 atatgtagta actgaagaag agagaaaaca cattttggat acatcatttg aaagtatgaa
      661 tcctttaaaa ttaaaagtat tttcttcaaa agaaaagaaa aaggtcgtaa ttttatctaa
      721 gattttggaa caatttgaac gtgggaagaa atattcagaa aaggaagtta atcagatttt
      781 agaatctata tatgatgatt ttgcaacaat tagaagatat ctaattgagt atggttttat
      841 gagtagaaat aaagaatgta caaaatattg gttaacataa ttaaaataat aaattttact
      901 aatgtgtaat gttattttta tctaggggga ggagtcaaat atgaatgatg aattaaaatc
      961 tattttatac aataaaggtg tggacattgt tcgctttgtt gatatatctg aatttccaat
     1021 aaatcaaacg caaggttttt ctaaagcaat tttattttgt atagggttat caaaaaaatt
     1081 tattacagat atatacaata acttacctac agatagtgat gagtttttag aaaaagagga
     1141 gaaagcagaa gaattagctg actggatttc agaatatatt caaaataaag gatatagagc
     1201 gtattctcaa tcggagaaaa acaatctaga acatggatat tttgaaaaag cctatattaa
     1261 tccagaaatg caatcaggga ttagtccttt accacataag acaatagcaa atattagtgg
     1321 cattggattt atgggaaaaa ataatttgtt tgtaacagag gaatacggat gtgcttttag
     1381 catgtgtaca gtacttacag atgctccaat ttctgttgaa agatatcctt tgattgattc
     1441 aaaatgtatg gattgtaatg tttgtgtaga aaactgccct gcaaaagcta tacatggaaa
     1501 tgagtggact ttgccaggaa aaagagagtc tattattgat gtttcaaagt gtttttgtgt
     1561 attgaagtgt atgatgagtt gcccatggtc attaagatat gcaaatcaaa aataatttta
     1621 ctagagaagg tattaaattg aatattataa aatttttaaa atgtaagatt atataagatt
     1681 tttcaaaata aaaatttgta tagaacactc agaaatgagt gtttttttat tggaattaaa
     1741 ttatattgat acaaagttta actattttaa tcattatata aaatttgtat taaaaaatta
     1801 agaataactt ggtaatagtg aaaatataat gagattataa ttgatttata atataactat
     1861 aatgatgttg taaaatgaaa attgtcattt caaaattccc aaaaagagta aaagtcactt
     1921 cggttatagt caaaaaattt tttcagtgaa aagaatttag atttaaaagg gaggaattaa
     1981 tcatggaaat tgaaactaaa actccggatt ggattaatgt actagaatta aacagtaaaa
     2041 tagatattac tgggaaatat gatgtaagta atattataca agatattgtc tctgataagt
     2101 cactagaagg ttccattata tattttccaa aaggtaatta tttatttgag aaaggtatta
     2161 aaattagtca acaaataaca cttcaaggag attcttatta tggaggagat aatcaagtat
     2221 caaatttaga taaaaaacaa tcaatcatag gaacaaccaa ttttataact cgaggagttt
     2281 ctaatatgag tattattgca ttgacaggaa caagtcaatg tatcaaaaat attaattttt
     2341 attatgatag tcatgatata gagaaaatac cgcctaaaaa tgtatctgct attacagaat
     2401 atggagaaac acaaggacta tctcattttg aacacctgtt tatttctgga ttttcaggga
     2461 tagggattga aattccatac tattcaactg gcaatgatat aattgttagt tcatgtggtc
     2521 ttggtatgag gcttggagag aagtcaatgc tttctagtag caagatttac gaatgtaaaa
     2581 atggaatgga gattactact ggtgttagct taaataatgt gagaatagaa gaaataaaag
     2641 aaataggtat taataataaa ggatttggtt ttaacctgat tatgaatctt atggtcgacc
     2701 aatgtggata ttgtggattt atgtttgaaa aaatgtgcta tagccagata actgccagaa
     2761 ttactagatg cggtcagtat tataaaagtg ttgattataa tgcttatgag aatatggaag
     2821 atagaaaaga aaaagcttat tccatttttt atggagatat tttagaaagt tgcaatattg
     2881 tattgatgaa tagaaatatt gataccttag aaagtgattc acttaatgaa cataagatat
     2941 atgtaatcaa ggcaaatgaa acaaacaatg taatgctaac atgttatgct gaagcagata
     3001 actttataca atgtgcaaag ggcaacttgc tgttagaaaa tggtgaaaat acttataaat
     3061 tttataatgg tgagatttgt tctgtaggag gtgttcaaat ttctgatata gatgaaaaag
     3121 atttaatcaa aataatagag aacactttgt atatagatga taaaggtaag tatttaatgg
     3181 ttcctagatt aaaaaagaat actgtaatat attcagtact agattctaca gaagaaataa
     3241 ataaattaca tggtggaata tgggaacaga ttgatgtaaa agtattagct ggggaatcca
     3301 tgtactatta taaaaagata aaagattaaa ttatcaaact aggaggtagt gattaatgga
     3361 agagtctata ataattaaag atataagtgg ctggattaat gtacttgatt atggaatttg
     3421 taatgatgaa acaaaagatg taagttttaa gttgcaagag attatggatg ctgtaccaga
     3481 agattctatt atatattttc caaaaggaaa atacttattt gaaagtggtg ttaagattaa
     3541 gaaacgatta accttatgtg gagattctta tattttagcg aatgttccta aaaatactgc
     3601 tggagtaaca cagtttactt ttaaaggaaa gaaaaatcct aaaagtgaaa atagagcaat
     3661 cataacagca aaaagtgtaa gacactgtat taagaacatt tgcttttatt cagatagttg
     3721 tgatagagat atgacatcta atcatgaacc tccaacagat ggaaaaccta gatttcatca
     3781 taatgtaatt ataaattata gaaatatatc tgctgttata tgtgaagata aacagggaga
     3841 accaggtcat tatgaaaatc tatcttttag tggtttttct ggaattgcac ttgatatgcc
     3901 taataattct acagcaaatg atattacaat ttttacatcc ggacttggaa ttagtacagg
     3961 ggaaaattca acaattgcta acagtaaggt ttggggctgt gttgatggaa tgataatttc
     4021 tactggaact tttataaatg gtatgagggt agaagaaata aaaaaagttg gaattaaaaa
     4081 tattggtaga ggtttaaatt ttattacaaa tatcacaatt gaccaatgtg gatattgtgg
     4141 agtttggttt gattctatat ccaatgttca gatatcagga aatatcacaa ggtgtgggca
     4201 gtactattat gatgtaagct atgataatta tttaatgttg gataatagag ttaaagaagc
     4261 atattcttta ttctatggta atttattgga gtcaagtaat atagttttat caaataccaa
     4321 tgaagataat tgggaagatt tcaaagaaga taagcataag gtgtatctta tagaagcact
     4381 taaaaccaag aatgtactat taacatgcaa tatagatgct actgactgga ttgttaagtc
     4441 agaaaaagga aatttaacgt acaataatat gcgacaaact gttatatttt acgatggaaa
     4501 actaagtagt atcaatggaa ttggtatatc tgatgaagat tatggggata aagtcaagat
     4561 aaaaaaagga aatatatata taaatagtaa tgataaggat attaagatgc ataaaccaga
     4621 ggtaggtgac attatgtcaa caattattaa agataaaagt attctttctg ctcattatgg
     4681 gggaacctgg gagaaaattg gtgaaaaaat agagtttgga ataactgtac actattataa
     4741 attgatagag aaataagtaa atacgtagta tttgaataga tgtattttat tggagagcta
     4801 ggactatagt tttaatataa atggtttggt aatagcatgg attgaataat ataaaaataa
     4861 tataaaaaat taatttgatt atgtaaattt ctatgaagta gtaaaactgt gactttagtc
     4921 ataggaggtt caaactaagt aaaagggaaa ggaatatata atattatgga aggaagaact
     4981 gggattaaag atggaagatg gattaatgta gtagaaagag gtattaaaaa tgatggttcg
     5041 tacaacatag gtcctgcttt gcaggatatt attgatgaaa tagaaacaga tttttgtgtc
     5101 ttatattttc caaaaggtaa atacctattt acaagtggtg ttaaaattaa taaagaaatt
     5161 gtattgcaag gtgattctaa ttcatctaca ggtactacac aatttataac tcgtggagta
     5221 gaaaatatga gtattattac attgacaggg aagaaacaat gtattaaaaa tataaatttc
     5281 tattctgata gttgtgagat acaggtaaat aaagaaccac cgacaaaagg taatcctaaa
     5341 tatcattatg agatgattat taataagaat gaaaagaatg ttgagatgaa taatgtatca
     5401 gcaatcctgt atgataacag taagaatatg attaaaggtc taggtcatta tgaaaatatt
     5461 tatataagtg gtttttcggg tacaggaatt aggataccat attactcaat tgtaaatgat
     5521 attacagttt catcttgtgg gctgggtatt gatacaggaa tagacacaat tatttctaat
     5581 agtagaatat ctaagtgtca aaatggaatg aggattagaa ctggaactag tataaataat
     5641 gtaaggattg aaaaaataca gaaagttggt cttataagta gtcaagttaa ggggtatgag
     5701 gggtatggaa gttataaaat taataatatt acgattgacc aatgtgggta ttgtggcttt
     5761 tcatttgatt caatgaaaga tagttatttt tctggtatta taagaaggtg tggtcagtat
     5821 tattataata cagattatga cacatattta agtattaaag atagagtaga agaagcatat
     5881 tctttatttt atggaaatta ttttacagaa tgtaatattg atttagttag tgataataag
     5941 gataactggg atgatggctt agaatataaa cataaagttt atgtatttaa aacccttcaa
     6001 ataccaaaat taacattgag atgcaatata gatgcctatg attatatcgt taaatcggta
     6061 catggaggag gtaatttaat gttaaaaaat aactttaaca attatatatt tattgattca
     6121 tctaatccag aagttattaa tggaattaat tttaattatc aaaagaatgg aaacttgtta
     6181 aggttaaata atggtaaatt aagttataaa aatggaaagg aagaaacagc tatattcaga
     6241 cctaattatg gtcttattgt agcatcaaca gattcagaat gtgaacaaat agaggctacc
     6301 tatggagaaa aatgggagaa gcttggttct gaagtaattg gagaagaaac ggtatattat
     6361 tataaacatc atgaaccaga taaaacaaac caaatacaat aaaatttgta ttatataatg
     6421 atataaagtt ttaatatata gtgtttacct ttaatgtaat attggtatat ttgtatagta
     6481 ttaaatttgt taaaaagtaa aattgtaggg tgcttgaaaa tagcaccttt tttagtttca
     6541 ttataaaatt agttttgaaa gtttaggaat aatgtatatt tatttttaaa gaattataac
     6601 cttattaagg atattttaaa tgctagaaat gaatcagtaa atcatactgg aattatctta
     6661 aatgttttga ttaaattaag tatttagagc tataattata ttaaaaatat attagaacat
     6721 aattatatta ctatggaggt taaatatgat agtaagtgtg agtagaagaa ctgatatacc
     6781 tgctttctat agtaagtggt tttttaacag acttgaagaa ggttttgttt atgtaattaa
     6841 tccaatgaat ccaaaacagg ttagtaagat agagttaaat ccacatactg ttgattgttt
     6901 tgtattttgg acaaaggatg taactccaat gttatatgat ttaaataaat taagagacta
     6961 taaatattat tttcactata ctataacatc atatggaaaa gaagtagaga catgtatttt
     7021 agataaaaga aaggtaatag attcatttaa ggaattgtct agaaaaatag gcaaagaaag
     7081 agtaatttta agatacgacc cgattttctt aagtgaaaag tacacagtag attatcatat
     7141 caaagcattt gcgagtttat gtaatcagct tgatggattt acagaaaaat gtataataag
     7201 ttttatcgat ttgtacaaga aaacaaaatt taatactaaa gcattacata taaagccaat
     7261 agaaattaca gaaatagaaa cattatcaaa agagattttt aagattgctc ataagcatgg
     7321 gataacactt gaaatgtgtt ctgaagaata taatttaagt aaatttggga ttggaaaaag
     7381 taagtgtatt gatgatagat taatatcaaa aattatagga tgtgaagtag aggtaaaaaa
     7441 agatagtaca caaagagata tttgtggatg tgttaaaagt gtcgatatag gacaatacaa
     7501 tacttgcaga cattattgtc tgtattgtta tgctaacttt aattatgcaa aagtagaaga
     7561 aaactgtagg ctttataaag aaggtaataa attactcata gatactttaa gagatgatgc
     7621 aaaaataagc attagagata tgaagactat taaagtagat aagaataaac aaattagtat
     7681 atttgattaa aataaatata ctaattacct taatatatta agaatataga tacttttgat
     7741 aacaaaatta aacttaatag atattttcta tataagaaag atggtcataa tatgtcaatt
     7801 tgaccatatt tttgatataa ttaaaacaca aataatttag taacaaagga ggcagaactt
     7861 gaatttatta aaaaaatatc ctatacctat tgcaagttta attttgtcaa tctttacttt
     7921 aggtaactta ttacaatctt atagtgaatc attacgtaat gtaattggat ttataggatt
     7981 tattttgtat gcaatttata tagtcaaaat agtattactt agaaagggtg ttaaagagca
     8041 attagagaac cctttaatat caagtacatt tccaactata acaatggcaa caatgatatt
     8101 tgctacatat ataaaaccat tatctttaga attaagtatt atgatttgga gcataggaat
     8161 tgtgggtcat cttgtgttaa tagtcttatt tagtaagaag ttcttagtta aattctcaat
     8221 aaaaacggta tttccatctt ggtatatagt atatgttggg atagttgcag ctagtgttac
     8281 ggcaccagca tttaatcaac ttttgattgg caaaattgct ttttggatag gatttgtatc
     8341 ttatatagtt cttataccag taattttaaa gagagtatgg ataatcaagg aaatgcctga
     8401 accatcttta ccaagtatag ctatattagc tgcaccaggg tcactattat tgtctggata
     8461 tattaattct ttttcagata aaaataatgt agtattatac ttgttattca tattatcaat
     8521 tgtattttat attatagttt tgggatattt accgaaatta ttaaggttgc ctttttatcc
     8581 gagttttgct gcatttacat tccctatggc aataagtgca atgggtatga aactaatgaa
     8641 tggttattta actaaatcag gtcattttat aagttggatt tcatatgctt ctaagttaga
     8701 agagataatt gctacagtga ttattttata tgttttagtt ttgtttatta tatgtcttag
     8761 taaatctgaa actacatcta aagctaaata agaattatta aatatgtgta tttaatagga
     8821 atattgatat aaatatatga agataagata aaccatagaa acttaattta gcttaatttt
     8881 attggaggaa aacaaatgaa aacaaaagaa gaatatttaa aagaagttag aaacatatca
     8941 gaagaatatt ttagaaaagg agagtttttt tgctctgaag cagttctcca gacaataaat
     9001 gatgctttag gccaaccttt aagtccagag ataactaagt tagcatcagg atttccaata
     9061 ggacttggaa aggcacaatg tctttgtgga gcaatatctg ggggagagat ggctttaggt
     9121 atagtatatg gaagagttca tggtgaagct atgaatccaa agatgtttga gcatgctaaa
     9181 ggtttgcatg attatattaa aaaagagtat ggtgcaacat gttgtagagc tattacaaag
     9241 aaatgggatg gtgataactt tatgtctccc gaaagaaaag agcactgtat taaaataaca
     9301 ggtcaagtta cagagtgggt tgcagataag cttatagaag atgaaaaact taatatcaaa
     9361 tagtgtaata ttagttggtg aatttataaa gttaaattta cttatagtat aagatacttg
     9421 atattctcgt attgatagaa aaatttatag catatgtatt taatgaaata tacttatatt
     9481 tagagtgtgg tttaatttca taaatacata tgctattatt ttaagtatat aagcaaattt
     9541 atttaaataa atagaaacag ttaatttata tgtacaaaac tatatatgat tagtgtaaat
     9601 aaatacctat tttataatac tcaacataaa gacaccagac atgattagta ttataccaat
     9661 aaaaatagca agccattctt ttttgttctt cttttcttta aaaaatataa tccctcctaa
     9721 agtggctact atcacacaac tctgagagat agaaaaactt attgtaactc ccaatgtatt
     9781 agtcgttatg aacataccta aatttgctat tgaccacaat ataccagtaa ttaaattgaa
     9841 taaaacattt tccctatata caatctcttt agaaaaatac ttgacaataa tagatgaagt
     9901 tatcaacata ccaacagatt gaggtaatat aattctgtat ccttcaatta aaaatatttg
     9961 attagttaca acatataatg ataaaaatag agatgataat aatacaactc caacacattt
    10021 taacatattt ttatctgtag attttttagt ttgataattt gtgagaagta taccaagtat
    10081 tatacataat attgataaag aaccaatcag taacatttta gaactggtcc attcattaaa
    10141 caagattaca gctaataatg tcgtaaaagt taattgtgaa ccatttgaaa ttggcattac
    10201 tttagataca ctagcaattt gaattgcttt aaactgcatt aattgtccca aactccagaa
    10261 tatgccagaa atcatactta tacaaaatga aaaaaatgta atttcaggat gtataaccag
    10321 agttattata gtggaaaata taaacgcact tatggatgta cctaaaagct gttcatgagg
    10381 agaacttttc tttagatttg caactatggg catcaatccc catcccatta caggaagtaa
    10441 agcaataatt attgtcagca ttaaactatt tcctttcata ttaaatttag acagctttta
    10501 atttatcatc taaaattaaa gtgttcaata cataaaaatt accgtattta atcaggaaat
    10561 attagtagtt ttttagaaaa acattttcca ttaaaataaa gacaaaggga aggagtaaaa
    10621 ttgaaaatgt taactgatat gattcaaaat cgtgaaatta aaataataaa gtttttatta
    10681 aaagaaggtc atacaactgt aaaagcaata gcagatgatt tagatgtttc agaaaaaaca
    10741 gtttcaaaat ctcttaaaga agtagaagca gtgcttaaaa agataggtct ttctttaata
    10801 agaaaaccta agataggtgt ttatattgat ggagatttaa aaaaaatact tccttaccta
    10861 gataataaag gaagtcaaat tcctacaacc agagaggaga gagttatcta tatatattca
    10921 gtacttttaa agagtaatga ttatattact atacaacaac tttctgatga actatatata
    10981 agtcgtggaa ctattgaaag ggatttagca gaagttgaaa aactgctaaa aaacgaaggg
    11041 atttccatat ataagaaacc tagtaaggga ataaagttaa atataagtga aagagataaa
    11101 agacaactta ctgctaagtt tatacataaa ttttggagta gaaactggta tattaagcaa
    11161 gagcaagaaa gcttttatca agcatttgaa aagatacagg cagatgtaaa tggtattttt
    11221 tcggaagatg atttatcaat aattattgat attcttagga atttcagcag agaaagaaaa
    11281 tttgagttct ctgattatga atttcagtca ttagttattc atttggcaat agctgtagag
    11341 agaattagaa aaggcgaata tatagaagaa agtttgtata ttggtaatat agaaaataat
    11401 caaatgtcaa ataccaatta tttagcaaaa caattagaag aaaaattttc aatattatta
    11461 ccaaaatctg aaattggata tataaattta catttagtag cgtctgacca acatagagat
    11521 actaatgaac taaaaaatac ttcaactaat ccttgtgaaa caagtacaaa taatatatca
    11581 aatcttcggg aaattataaa aaatacattg tatgagacag cttatgacaa ggatttaatt
    11641 gatggattga cttcacatgt acattcatca ataaatagac tgaaatatgg acttagtatt
    11701 aaaaatccat atgtaaatac aatcaaacaa aacttttctt tatcatttga gcaagcttta
    11761 gatttaaaga aagtaattga atttatatat gatattagga taaatgatga tgaatgtgct
    11821 tatatagcat tacattttga agcttttaga gaaagaatga aagaacttcc acaaaatatt
    11881 agagtaattc tagtatgcag tacaggatta ggttcatcta ggttattgtc tgcaagaata
    11941 aaaaaatact ttccaatgat aaagattgaa aaagtacttt ccgtacaaga attagtatcc
    12001 agtaaaattg atgcagattt agtaataagt actatttatt tagagttaga aacaattcca
    12061 accatagtag ttagtcctat tttaaatgaa agtgatataa gaaccttgga aagaaatata
    12121 caaaatgttt caagttgtac ttctaagaag tataaatctt tcagaaactt aatctttgaa
    12181 gaaaatatat tgttaaatat tgaagcttca aattatgaag atgcaattaa tcatataaca
    12241 gataacctaa taaaaaaagg ttttgcaaaa gaaggtatag ctaaaagtgc aattgagaga
    12301 gaaaatttat cttacacgtc tttccagtca atagctacac ctcatgctaa tcctagttat
    12361 attaaaaaat ctaatatatc tgttgcaacg ttaaaaaatc ctattacatg gggaaatgaa
    12421 aaggtggaag ttattttctt tatttcatta gaaaatgaca aaaacctaga gcttgatgaa
    12481 atatatgaag ttttttatga ctttattgac aataaaaaaa atataaatga catattaagt
    12541 gcaacttcca caaaggaagt gtacgatttg ctagtggagg agagtatata gtgaaaatat
    12601 cagatgtatt gaaaaaagag caaattgttt ttaatcttga tacaaataca aaggaagaaa
    12661 caataaaaaa attaagtagt atatttgttg aaaatgggat tgtggacaat gaagaagaat
    12721 atgttaagtc tgttttggaa agagaagaac attcaactac aggtattggt aatggtattg
    12781 ctattcctca tggaaaaagt aatgctgtca aaaaatcttc tataatattt gcaaagacta
    12841 agcataagat tgagtgggat gctttagatg aaaaaccagt agatagtatt ttcttattgg
    12901 ctataagcaa tgttgataag gatagcaatc atcttgtact attatctaaa ttagcaacta
    12961 aacttatgga tgatgacaat gtagatgcac taaaattagc caattcagaa caagaaataa
    13021 tcaatatatt tagtgaagaa ggagagatgt agaaatgaaa agaaaaatta tagcagttac
    13081 agcatgtgca acaggagttg cacatacata tatggcagct caagcattaa agaaagcttc
    13141 aaaaaagatg ggtcacctta taaaagttga aacacaagga gctacaggaa tcgataatga
    13201 gttaactaca aaggatgcac aaattgcaga agtagtaata tttgcagtag atactaaagt
    13261 cagaaatgct gaacgttttg agggaaaaga aatactagaa gtaccagtta atgcacctat
    13321 aaaggatgca gagaaagtaa taaatgatgc actaaagtta attgacacta aataaatgga
    13381 gggaaatata atgttgaaaa agatagtctc tgagttaaaa aagcatgtct taactggaat
    13441 ctcatatatg attccattag taattgcagg tgctatgata atggcgatat ctcgtgtagg
    13501 tggttctttc tataatatac cagatatatg ggatgctaaa tatgcagaaa gtgctagtag
    13561 tattgttaga ttattacatg atttagatgg gtttggaggt actgcattag gattaatgtt
    13621 tcctgtaatt gctgcattta taggattttc tatagctgat aaattagcta ttgtaccagg
    13681 tcttgttgga ggtatgattg ctaaagatat aggtgcagga tttttaggag ctttggcagt
    13741 tggtcttata gcaggatata catgtttgtt tattaaaaat catgttaaat taccaaaatc
    13801 agcagcttca atagtaccaa tatttatagt accagtattt gggacattaa tcactgttgt
    13861 attaatcaat tatgtgatag gtataccttt tgccacatta aatactggat tagaaaattg
    13921 gttaaatgga ttatctggta caaatcagat attaatggca gctattatag gggctatgat
    13981 ggcagttgac ttaggtggac cagttaataa agcagcttta acaacatcac ttgcattatt
    14041 aacaagtgga atttatgcgc ctaacactgc tgcaatggta ggaatagtta taccaccact
    14101 aggattggga cttgctacta tactagcaaa acaaaaatat aataaacagt tacgtgaagc
    14161 tgggaaatca tctcttataa tgggtttaat tggagtaagt gaaggagcaa ttccttttgc
    14221 agtagaatct ccattaaaag taataccttc atgtgtaatt ggaacagcaa ttgcttcagc
    14281 tatggcagtt ggtttaggtt cagtaaatgc aactccaatt agtggatttt atggatggtt
    14341 tacagtagag aattggccaa tgtatgtgtt atcaatagca gttggaacag taattgtagc
    14401 tggattagtt atagtattgc gtggaaatcc agtgattgag gatgatgaat ttgaagatga
    14461 tgattttgat gaagcagagt gggaatctta aaatttaata actatttaag acgtgttata
    14521 agctatattc aatatgaatc ttatactaaa taaagtgtta aatattcagt ttagacttaa
    14581 atataaaaga taaagaacag aggagaataa atgataaaag cacatattgt taatcataca
    14641 cactgggata gagaatggta ttttacttct ggagatgcat tagtacttag tgaacaacta
    14701 tttacagatg taattgatga attagaacgt aatccagatg taagttttgt acttgatgga
    14761 caactttcta ttttggatga ttatgtacaa ttacacaaag aaaaaataga aatcattaaa
    14821 aagttaataa aagaagatag actacatatt ggaccatggt ttactcaaac tgatgcattc
    14881 tttgctagag gagagtctat tttaagaaac ttaatgattg gaatttttga aagtaaaaag
    14941 tatggtaagt atatgaaaat tgggtatttg ccagatacat ttggatttaa tgcacagatg
    15001 cctatactat taaagcatgt aggtcttgat aatatattct tttggagagg tatacatctt
    15061 ggtaaacagg ttcaatcacc atattttaag tggaaaagct taaatggaga aagttatata
    15121 tatgcagtaa atatgccaca tggatatgga actggtatgc ttttagagcc ttcattaaag
    15181 tatgttaatg gacgcttaga cccagctatt gattttatta aatcatatac tgatgtagat
    15241 gaggtgttaa taccttctgg gaatgaccag ttaaatataa taggtgattt caaaaataaa
    15301 attaaagcga ttaatgatat cggaaagtat tcatatataa cgagttcata tcaagagttt
    15361 ttaaaatata taaagtccat agaatcacta gaaagctata gaggtgaatt tagagaacct
    15421 gtattagcaa gaatacataa atcaattggt tctagtagaa tggatataaa attagcatgt
    15481 gataaactag aaaacaagct gattaaaaga atagagccat tattagtaat tgctaaaaag
    15541 agtaaaattg aaataagcaa tcagttactt ataaatacat ggaaaaaact tttggaagga
    15601 caagcacacg atagtttagc tggatgtgta actgatactg taacagatga tattcttcac
    15661 cgtataagag aagcaaatga aatatgtgac agtattgaaa atactattgt aaaaaagatt
    15721 tcagaagggc ttaaattatc taaaaatgat attttagtat tcaatacaga agctaagcgt
    15781 tttaatggat ataaagagat acaagttgta agtgatagta aaaatattta ttttaaagat
    15841 aatttagatg ctactataat tgaagaaact tatgtaaaat cgagagaaaa tgtattagaa
    15901 gaaacacctg ctggtaatat atttattgaa gaaccaggat attatatatt aaaagtaaga
    15961 ataaatatac agcttcctgc acttggttat aaagttgtta gttttgaatc aagtgataaa
    16021 gaaatggtgt cacttgataa atctaatgac acttttatat ctaatgataa ttataagata
    16081 atatatgaag atggaagctt aaatttacaa cttaaagatg gaacttacat atcaaacttt
    16141 ttaacattaa aagatagtgg taatgcaggt gatacctatg acttttctcc actaaaaaat
    16201 gatgaggata taaaactttc gtttgataaa gtgtatacag aaaaagcttt aggatatgaa
    16261 aaaatggtag ttaaaggtac tactttacta ccacttacat tagaagatag aaaaaacaaa
    16321 tatcttaatg ggaaattaaa tgtaaaagta agtattgtct tatccaaaga aaatccattg
    16381 atggatgtaa aactttgtgt tgataacacg atatataatc atagactacg tgttcatata
    16441 aaaactgata taaaagataa taaaaacata gcatcattgc catttggata tataacaaga
    16501 aaaaatggag ttttagacaa ctgggaagat atttacagtg aaatgcctat agatttagaa
    16561 cctttggaaa gtaatattac gcttacaaac caaaatagaa gttgtactgt atttactaga
    16621 ggaataaaag agtatcaaca tattgaagat gaaattgcat tgaccttact tgctactaca
    16681 gatgaactag gaaagcctga tttattatat agaccaggac gtgcttctgg tgatacaact
    16741 aaaaaaggtc atataagaat taaaacagat aaagctcaaa tgcttaagaa attagaattt
    16801 tcatttgcaa tatatatgga ttctaaatca tttgatgaat tggaaattgc gaatttaacc
    16861 cacaattatc taagggaatg tgtaaattat caattacagg attacaattt ctttttatat
    16921 cgtatagata ataagattca aaaatcaatt gtcaataaaa ctgtaagtag agaattagaa
    16981 ataatatctt taccagaaaa ctatcttata tcagcatgtt atccttctta ttacagtaaa
    17041 gataaattta taataagagt ggaaaatcca agtagtaata gaatgatatt ggatgagcaa
    17101 atatttaaaa atagaaatgg gaaaattgta aatgcaatag aagatgtaga agaggaacag
    17161 gtatatgaaa tagcaccttt tgacgttatt tcaatactat tggatttata agtgtaaaag
    17221 taagtttatt gtttaaagtc tgacagatat taatctgcca gactttttaa tttgtataaa
    17281 tttgggtaaa tattaatgaa tggttttagt atttaagtat gaatttagta tttaatatag
    17341 aatttattga agtagaataa ttagtttaac aggataagca gtttaaataa agaattatta
    17401 tattagagtg attttatata taatttaaaa taataaaatt ttaataaaat gagttaaaga
    17461 ttgtatatta atagagttga tgtagttaca aaaaagttac caattgttat gtatttacaa
    17521 aactgatata ttaattacat aaaatctaaa atagtttgta ataggagtat atataataaa
    17581 aattttaatt aaataaagct aggtatattt ataatattaa taaatatatt gctataaaag
    17641 tttgtttaat aaattaaata aagaaaagag gagaataaaa tgtacaacat agatgatatg
    17701 atatataatt gtccagtaga agctttatca aatattttag gtaaaaaatg ggtggctata
    17761 attatatgga aaatacaaga agataaaaaa cgatttggag agctacaaag agctatacca
    17821 gactgtagta agaaaatgtt agttcaacaa ctagattttt taattgaaca ggggattata
    17881 gtcaaccaaa aaaagttggt taataatgtt gtagagtcaa catatttttt aagtgaatca
    17941 ggattacgat tgcttcctgt catggaaaaa atgattatgt ggagcaataa aaatttaaat
    18001 tgtgataaat actaaaattt actctgtaag taatgaaaat ttaattaagc tatgagtaga
    18061 aaaatgtatt aaaattacat aattttttag ttagatttta atttagaaat gggattgtaa
    18121 tattggaaat aaaataagga ggaattttaa tttgcaaaat gtaaatttat ttttagtatt
    18181 tatagaaggt atagtatcat tcttttcacc atgtatactg ccaattttgc ctatttattt
    18241 gagtatattg tcaaatagta gtgtagaaaa tttaaaagaa ggaaagacga gttttatagg
    18301 aagttcttta tttaaaaata ctatattttt tgctcttgga atctcaacaa cattctttat
    18361 attgggttca tcagtaaaag tattgagtat gttttttaat gaaaataaag atttaataat
    18421 gtttattggt gggattataa ttattatcat gggattattt tacatgggaa taattaaatc
    18481 ttcaatattg aatagagaaa aaagatttaa tgttaagttt aaagaaatga aagcaataac
    18541 agcttttata ttaggtttta cgtttagttt tggatggaca ccttgtattg gtccaatatt
    18601 ggcatctgta ttagtcatgg tttcaagttc aagtaatcat cttagtgcca atcttttaat
    18661 agcagtatat actattggtt ttattttgcc attcataatt acagctatgt tttacagtaa
    18721 actatttaaa actatagata agataagatc taacatggaa attattaaaa aaataggtgg
    18781 gattatactt atagtatcag gaatattaat gatggtaaat ggatttggaa gtataagcaa
    18841 acactttaat acgtcacaaa atagtaaaat tgaaagcaag caagaagaaa ataagcgaga
    18901 aaattctact gataaagaag aaaattctga tggtaatgat agtcaaaaag actctaataa
    18961 tgacaataat gataaagggt ctaatgatga agatagaata aagtctattg attttacttt
    19021 aacagaccag tatggtaaaa cacataaatt aagtgattat gaaggcaaag ttgtattctt
    19081 aaatttctgg gctacatggt gtcctccatg caaagaagaa atgccttata tagaacaact
    19141 gtataaagac tataataaaa ataatgatga tgtagtaatt ttaggagtag cttcacctaa
    19201 tttaggtaga gaaggttcaa gggaacatgt agttaacttc ttaaaagacc aaggttatac
    19261 attccctgtt gtacttgatg aagatggagc attagcatat caatatggaa ttaatgcttt
    19321 tccaactaca tttataattg acaaggaagg atatgtaact cagtatattc caggagctat
    19381 ggataaggca actatggcat catttattga aaatcagaga aataaataaa agtatttaag
    19441 tataagttta taaatcaatt taaggttaca aaaaagtgcc taattgtacc acctaaataa
    19501 tcttgttata gtaaaagtat aaacaataca agaaagggtt gaattttata tgaaaaaaac
    19561 atttgatgct ataataatag gatttggaaa aggtggaaaa acattagcag gggatttggc
    19621 aaacagggga ttaaaagtag ctttaataga aaagtcaaac aagatgtatg gtggaacatg
    19681 tgtaaatgtg gcatgtatac caacaaaaag cttagaaaat tcagcaaaca gcgtaaaaac
    19741 aaagaatata aattcttggg atgaagtaca agctgaatat gagaaagcta tagataaaaa
    19801 agaaacttta attacaaaac tcagagaagc taactataat aaattaaatt caaatgagaa
    19861 tgtaactata ttcacaggaa tgggaacttt cattgatgaa aaaacagttc aagtcaaaac
    19921 tgaaaatgaa atttatgagt tagtagcaga taatatattt attaatactg gttcaagacc
    19981 atttatacct aatattaagg gaattgaaaa taagaatata gtatatgata gtgagtctct
    20041 tatgaatcta agaactttac ctaaaaaaat gacaattata ggagctggat ttataggttt
    20101 agaatttgct ggtatttata gttcatttgg agcagaagtt acaatattaa actctaataa
    20161 tggcatttta ccaaatgaag atgttgagga ttcagaagaa ataataaaat tacttgcaaa
    20221 gagaaatgta aaaattgtta ataatgcaaa tataaaagag attaaagaag tttctgaatt
    20281 agcaatagta gaatatgaag tagatggtaa atctaaagaa ttaacaagta atatgatact
    20341 tgtagctaca ggaagaaaag caaacactga agggctaggg ctagaaaatg caggtataga
    20401 attaaatgaa agaggattta ttaaagtctc agaaactctt aagactaata aagagcatat
    20461 atgggctata ggagatataa atggaggtcc acaatttact tatatttcat tggatgatta
    20521 tcgcatagtt attaatcagt tatttggaga taagactaga acaactaatg atagaaagaa
    20581 tatcccaaat tctatattta taagtccagc attttcaaga gttggtctta atgttaagca
    20641 agctaaagaa aagggatatg aagtattagt ggcaaagatg ccagtagaag caattccaag
    20701 agctaaacag attggcaagg cagatgggtt tataaaaata gtgatagata aaaaatccaa
    20761 taagatactt ggagctagta tgatatgtga aaattcaagt gagattatcc atcttattca
    20821 attagctgta gatttagaag tagagtatac atatttaaga gaccgtgttt atgcacatcc
    20881 aactatgaca gaagctctta atgatattct atctcctaat atgataaaag aagtataaca
    20941 taagtttaat atataaacct aaaattatca ttataagtag attttagaaa gaggctatct
    21001 caaaaaatag agataagtct cttttttact gtttaaatga taaaaatata tttgatttta
    21061 taaaagaaga ttatcttatg aactaaaaag tttattttaa aacactacct atttatgtta
    21121 taaacttata aatataatat agaatctatt attctgtatt attaagtggg gttaagcgtt
    21181 ataattaatt ataaatattg aataatctaa atggataaga taatggtatt aaaaattatc
    21241 ttaaaaggtg aaataatctg tatttaatgt agtacagtta tatctttaaa gcaaggtggt
    21301 gaaatgatat aaataagata tctaaaagag ggtttgatga tggtgataaa agatggtttt
    21361 caagtaaaga attaacaaga cttataaagg ctaaagaaga aatagaatgg ttattaaata
    21421 gggattacaa aatagaccca gtcgttactt ttgttggtga tagatatcag ttttctataa
    21481 gacaaagaga tgcattaaaa agggcagtct gtactgatga aaaaaatatt ataagacaat
    21541 caaaaaggct ttctctagat aaaatcaaag aagataccgt aaatatagat ggctttaatt
    21601 tgataatatc catagaggta gcattatctg gtggtactct agtaatagga agtgatggca
    21661 atataagaga tttagcaggt cttaggggaa cctataagat tatagataaa acagaagaag
    21721 ctttgaatct gataggtaaa ttttttaata aatacaatgc acagaatctt aaattttatt
    21781 tagatgctcc agtttctaat tcaggaaatt taaagtatag gatattagag catgccaaaa
    21841 cttggggaat tgaaactgaa gtagaattag taaaaaatgc agatgttgta ttggaaaaat
    21901 tagatagagt agttagtagt gatgcagtca tagttgacaa gtgtataagt tattttaatg
    21961 tggctagagg tataattgaa gagtatatta aagaatgtaa tatcataaat ttaaataaat
    22021 agataaatat agatgagaat atataagtat atgtagcaat attattagta atacaagtaa
    22081 agtttgaaaa taggagaacg aatacatatc gaatttcata aaatgttgta aaaagacata
    22141 tgagaggatg gatatgtgtg aaattaacta aactaaatat taaaaaatat agagcaccta
    22201 tatataaata tgctttagca aatgtaaatt tgaggtctgc taaatctacc aattcaagta
    22261 tcataacagt aatacctcag ggagctaaaa tggaagtatt ggatgaggaa gatgactgga
    22321 ttaaggtgat gtacaattct caagaaggat atgtgtataa ggatttggta tcagtaagcg
    22381 aatatgcttg gagtaactta aacttaagag aagataaatc tacaacttcc aatataatta
    22441 cagtaattcc tgaaaaatct agggttgaag tccttcaagt agatggagat tggagtaagg
    22501 ttgtatatga tgataaaata ggatatgttt ttaattattt tttatcaatt gatgggaata
    22561 aaccaaatga attagattat aagtattttt atactgacat gattaaattt gttaacgaaa
    22621 ataatattaa aagtactagc gattatctaa ttgtaacaga ccttagaaat aaatatactt
    22681 atatttttaa gaaagataat ggaggctggg gacaacttta caagtggcaa tgtaccatag
    22741 gtaagcctga gactccaact ataacaggta tattttatat aagtggaaga aaaccttctt
    22801 ttggaacgga tgagtattca gttaagtatg ctactagaat taaaggtgga tattactatc
    22861 attctgtact atatgattca acaggaagtt atataataga tggcagactt ggtgaagctc
    22921 ttagtcatgg atgtataaga ttaagtacgg aaaatgcaaa gtggatatat gataatatac
    22981 cagatacaac aacagttata attcattaag aaaaattttg agttttttat tgggataatg
    23041 attcttaaat taataggatt atatattaac ttctcataaa gagtactatt taaaaagtgt
    23101 aataagagag tgctattaac aaaacaaaga tattttgagg cactctctta taaatataca
    23161 taattaagat attttcataa acaattctat aatcttatct ttatcaaaga aaacaggatt
    23221 agcaccagca caagcatctt tcatagagtt ttctgcaagc aattcaaaat taggattatc
    23281 aacacctaca tcttttaaag attttgggat tccaacctct tcagaaagag cttttatctt
    23341 atctattaca aagtcaacac actctttatc tgatttatta tttacatcca ttccaataac
    23401 ttcagctatt ggtcggaatt tggcaggggc tgatttagca ttttcctcct caactattgg
    23461 aagtagcatg gcattacata ctccatgagg taaatcatat aaacctccta attgatgagc
    23521 catagcatgt acatttccaa gacctgcatt actaaaggca attccattta aaaaacaagc
    23581 ataacacatt tgttctctag cttctatgtc attaccattt ttaacagctc ttggaaggta
    23641 tttaaatatc tgctttatag catataaggc agttgaatct gtaacatcat aagcaccatt
    23701 agctactaca gcttctatag catgagttag tgcatccata ccagttgctg ctgttaaatt
    23761 agatggtttg ctaatcatta attctgggtc atttactgtc attgtagcta gtgaattggt
    23821 atcaaccatt atcatcttta catgtctgtc ttcatcagtt ataacatagt ttattgtaac
    23881 ttcagcagat gtaccagcag tagtagttat agctatgata ggaagacatt ttttagaagt
    23941 tttgttgata ccttcatagt ctctaatatc tcctccatta gtggctaata tagagatagc
    24001 tttaccacag tcttgtggag aaccacctcc tatagttata acgaagtcgc aattttctga
    24061 tttcaatatt ttaagtcctt tattcacatt agttacagtt ggattttgtt taacttcatc
    24121 ataaacaaca aagtctatat ctatctgaga taaaatatct gttacttttt ttacagtacc
    24181 atttgaaact agaaatttat cactaacaat aaatgctttt ttagttccta atgatttaat
    24241 tgaatcttta gcttcattaa gacatccttt cccaagtaaa tttattggtg gtacataata
    24301 aatgctcata actaaaatct ccttttattt tcattgattt ttatgtaaaa atatatatct
    24361 aacaattttc actaatttac tcataatata tcgtatctta gattgagata gggttgttgg
    24421 ttcttatata agaacttaat tcgtaattac gattatgatt agaatttaac atagtatttt
    24481 tatcatgtca ataaaaatat aaaaaatatt ataaaaaaaa caaagttact gtagttaaat
    24541 cagcaacttt gtttttatag tataaatcaa ataaatacat tagtttaaaa caaaattttt
    24601 aattattatg ttttgatatc ttccatatac agaatattaa tctaatttat tacaatgtct
    24661 tcattacgtt cttccatcat tgattgaata tttttctgag catttaagag taattttttt
    24721 atcagttcta ttttttcgtc attagctcta aataaaggca gtgttacact aacagcagct
    24781 cttatacatc cattttttct tattggtacg gcaagacatt ttaggtgttc cattgattcc
    24841 tcacactctg aagctatttg tgttctttga acttcaagaa gctggtcgta taaaacatca
    24901 aaatctgtaa ttgatttttc tgtaaaacct tttagaccat ctggatataa gcttattagt
    24961 ttttccttgt caaaatcaca taaaagagct tttccaagac ctgtacaatt agcaggtatt
    25021 ttttttccaa cataagaaat aagtctaatt ggttctggag aatctacttt tccaatataa
    25081 agaacttcat tattgtcaag tataccaagc tgacaagttt cagaacagga attaactata
    25141 ttagtcattt cgtcaattat atagttaaaa atagttcttt tttcaaaaaa tgaagaccct
    25201 aatgtgtaag aacgtatccc tatagaatat ttggatgtgt ttttatcaat agtaatgtat
    25261 tttctagcat taagtgtatg aactatagga aagatgctac tttttggagc attgataaca
    25321 tctgctattt ctgtaagagt atatccattt tcggattctg ctaatgcttc taaaatatct
    25381 aatatcctag ctgttgggcg atgattatct gaagtcataa atttccccct ctttttatta
    25441 atttaaagta ttagaatatg ttgattttag cacactatac gatattttac aatgtagaaa
    25501 ataaatatgt aaatttatat ataaataagc tcttgattta gatacagata gatatttttt
    25561 tagactgtac attaaggaat aactaatttc caaaatatac ctaaagaaag taagtgatat
    25621 ttagttatat aatttaagta aatatatgaa atagttattt ttatatgtaa atatgaaaat
    25681 attatgaact tatattttat ctatttttta cactgtataa aaactttata gttttgaata
    25741 ctatataatt ttaaatacgc tgtatttttg catataagga agtcatttga taatatacaa
    25801 ggtattatca gaaagtttga aaaaattttg acaaaaattt atttttttta ttgactcata
    25861 aataggaaaa tgctatcatt aattcaaaga ttcgtaatta aaaacttagt tcttaaatac
    25921 gaaccgaaac ggccgttaga attaaagcta aaaacttaat aagagtaatt aaatatcatg
    25981 ttttaggagg attaacttta tgataatgga ttttattaaa aaaattcctg caggtatgat
    26041 gatagtgcca atgtttatag cagctttcat taataccttt tgcccagata ttgtacaaat
    26101 aggttcgttt acgacagcag tattttcaag tgttgggtct gcaactataa ttggggttca
    26161 actggtatgc ttgggaactc agcttcaatt tagagaaatg ccaaaagttt taaagagagg
    26221 tggtatactt cttggttcta aatttgctat aggtgctttg ataggtatac ttataggaaa
    26281 gctatttgga atggatggtg tccttggtct gacaacattg gctgttataa gtgcagttac
    26341 aaatagtaat ggtagtatat atctttcatt gatgacttca tatggagatg aaacagattg
    26401 tgcaactatg agtttactta ctttaaatga tggaccattt tttacattaa tagctcttgg
    26461 gacttcaggt cttgcaaatg taccattgtt gtcattattg gctgcaatag tgccaatact
    26521 tgttggtatg ataataggaa attttgacaa aaaaatgaaa gagtttttag agccagggtg
    26581 taatttactc gtaccttttg tagggtttgc acttggtagt agcataaatc ttgcaagtat
    26641 actaaaagga ggtttatcag gagtattact tggattaata tctgtatttg taggaggtat
    26701 atttatagta ttctgtgata aatttatagg aaaacgtcca ggatatgcag gatgggctgt
    26761 agctacaact gctggaaatg caattgctgt acctgctgct gttgcattag ttgacccatc
    26821 atggcaacca tatgttgcaa cagctacaac acaagtggca gccgcagtag ttgtcactgc
    26881 aatattagta cctcttataa ctagttggtg ggctaagaag tatggatgtc ctaagttccc
    26941 aaaacaaaat gaggatggta caataacagc ttaatttata ttacagtgag ttgttggtaa
    27001 aataataaat tctttaatta gattttagga tattaataaa attatattat ttataaagga
    27061 gagcaagaat aatgataaat gcagtgataa ttgatgaaaa agataatgtt gcagtagcta
    27121 ttgaagcaat agctaaaggt agtgaaatta gttttaaatt aaaagacaaa acagtaaaaa
    27181 cgattacagc actagatgat ataactattt atcataaatt ggctataaaa gatatggccc
    27241 aaggtgataa agttactaaa tatggtgaac atataggaga agcaaatcag gaaataaaaa
    27301 gtggtcaaca tgtacatatt cataatgtta gaagtgttag agaggatttg gataaacaag
    27361 ttatgactaa tatataaaat aattttatag agttataaaa gttgtattca ttgcttttag
    27421 tgtcaaatag tttttaaata ggtttttagc tgtttgatta gtgagtgtaa taaaaattat
    27481 aatatataaa aattatagaa agtatataga ctattttagg aggaaatcag tatgaaattt
    27541 tatggatata aaagaccaga tggaagagtt ggtataagaa accacatatt aatattgcct
    27601 acgagtgtgt gtgcatcaga tacaactaga ataatagcat cacaagttca aggggcagtt
    27661 acctttaata atcagaatgg atgttcacaa gtacattcag accaacaatt aactatggat
    27721 gttatggctg gttatgcagc aaatccaaat gtatatggtg taatagttgt atctttggga
    27781 tgcgaaaatt gccaaaatga tttggtagtt gatgcaataa aagagagaac aaataagcca
    27841 ataaaaactc ttgtaataca agaagaacat ggaactttaa aaactataga aaaagctgtt
    27901 cgttatgcta gagaaatggc acaagaagct tctttgctta gaaaagaaga atttccaata
    27961 tctgaactta tactaggaac tgaatgtggt gggtctgacc caacaagtgg attagcagca
    28021 aatccattaa taggtgaatt aagtgataaa cttgtcgatt taggagcaac atcaatttta
    28081 agtgaaacta ctgaatttat aggtgcagag catatactag ctaggagagc agtaaatgaa
    28141 gaagtaaaag aaaaaatatt acatatagta catagatatg aaaattcatt aaaattggtt
    28201 ggagaagaag ttagagaagg taatccatct cctggaaata tagctggtgg tttaacaagt
    28261 ttagaagaaa aatcacttgg ttgtatacat aaaggtggtc atagacaaat aagtgaagta
    28321 tatgattatg ccaaacaaat tgataagaaa ggtcttgtta taatggatac ccctggaaat
    28381 gatgcttcat ctgttgctgg tatggtagca ggaggagcac aaatagtggt atttagtaca
    28441 ggaagaggaa caccatcagg aaatccaata gcaccagtaa taaaaataac tggaaataaa
    28501 ataacttttg caaatatgga agataatatg gattttgatg ctagtccagt tatctatggt
    28561 ccacaaacaa tggaagaatt aacagatgat ttgttaaata tggttgtaga tgtagcaaat
    28621 ggaaaacaat caaaagcaga gtcccttgga tatactgaaa tggcaatagc tagagtatgc
    28681 aactatgtat aatctttaag taagaaaata aatacataga attttaataa agggtgagat
    28741 tatgaagttt gtaagtttta ctgaaggaga aaatgaatgt aaaagaactg gagttttttc
    28801 taaagatgaa ttatttatta tagatgttaa ctctttaaat ctcagtagaa attttaagga
    28861 tttaaatgaa ttaattcaaa atgtatctag tgaagatatt attaagttga aaactattat
    28921 aaatgaaagt acattctata attatgatgt ttttaaaaga gagagatgta cggtacatgt
    28981 tcctatagaa aaaccaatac atgatatctt atgtgtggga gtgaactata aagaccatct
    29041 tgaagaaact caaactcact ttgatgatag ttttgaagaa ccacaaaaaa cggtttattt
    29101 tacaaaacgt gtgacaaagg caataggtcc agaagatgag atagatggtc attttgagat
    29161 aaataatcaa ctagactatg aagttgaact tggagtagta ataggtaaaa caggtgttaa
    29221 tattagaaaa gaagaggtag aagattatat ctttggttac actgttataa atgatatttc
    29281 tgctagaaag ttgcaaaaag aacatgttca atggtttaga ggaaaaggat tagatacatt
    29341 tacctcttta ggtccatgta ttttacataa aagtgcagtt ccttttccca taaaacttaa
    29401 agtatgtagt agggtaaatg gtgaagaaag acaaagttct aatacaggat tattcatatc
    29461 agacgtttca gacatagttt cagaactttc aaaaggtatg actttagagg ctggagacat
    29521 tatagctact ggaacacctt ctggagtagg gatgggattt tcacctcctc gatatatgag
    29581 tagtggagat gtagttgaat gtgagattga gagtattgga attttaaaaa attacattaa
    29641 gtaaatgttt taatataatt aatattaaag ctaaatctga tgtattaatg aacatattaa
    29701 aataaatttt aggagtttaa attatgaaag cagaattttt gacaccagtt gttacaatat
    29761 ttgatgaaga aggaaattta gataaagaag gtaataaaaa agtgtatgac catcttatag
    29821 atggaggtgt agatggacta gtcataatgg gaagtactgg agagttcttt aatatgtcta
    29881 tggatatgca aaaagaactt atagatttag taactagtca tgtaaataag agagtaaaag
    29941 tgtttatagg tacaagtcgt atgtgtataa atgaatctat agaactttca aactatgcac
    30001 ataatagtgg agcagatggt gttatgataa taagccctta ttatttctct cttgatgatg
    30061 atagtattga gttattttat agtgaaatag ctaagaatac agaggctgaa atatatttgt
    30121 acaattatcc agatagaact ggttatgatt taagtccaga acttacatta agacttgcaa
    30181 gaaaacataa aaacatagtt ggatataagg atacagtaac tttgatggga cataccagag
    30241 atttaataaa tactatgaaa atagagttcc cagaatttaa ggtttatagt ggttatgatg
    30301 aaaactttat acataatcta atgtctgggg gagcaggttg tatagggggg ttatcaaatt
    30361 taattccaga agtttgctcc aaatgggctg aagcttacaa taatagagat atggagaagg
    30421 ttatagaaat tcaaaaatat attaataaag caatggattt ttacttaata accaatccat
    30481 ttataccagc aatgaaaaaa gctatgaata tcagagggtt acaaataagt gattatatga
    30541 ctgctccatt tgtaaaacca aatgaaaaac aagtatgtga aattaaaaaa ttgatgaatg
    30601 aattaaatat atgttaactt actaagtaag atatatgagc aaaaaaagag tgtttaaact
    30661 gatttttata atcattttaa acactctttt tatatatgtt aaatcaactt tgaaaagtgg
    30721 tcaacaataa attacaatta tgttaataaa aattaaataa tactaagata gcagattagt
    30781 ttaaaagtta gcacaaatat taaagcaata gcctttatct attaaaaata atcttggagt
    30841 tttacaaaca tttttagata agtataagtt aacaataaga gccacatata aactactaca
    30901 aatcatgtaa taattaatct aataaatgat aaacacttag acttcaagct taaaagtata
    30961 aagataaatg aatttacata tcaagattgg caataatttt gtgatacaaa gcactatagt
    31021 aagaatgatt taataccaat gattttgaaa gaacatatag aaaaatacaa ttagaataaa
    31081 ataaatttta gagggaaggc attgccttcc attttttgtg tttttctaga attgggtaaa
    31141 ttttacgatt ctagtaaagc acaaaagaaa atctgttggt cttgaacatt ttatattagt
    31201 aattataggt agcaatatac aattactaca aaagtgaaat attaatgaaa tgtaaatcaa
    31261 tttaaaaaaa ttaaattaaa aattacaata gatatataag aaatttaaag gagaaataag
    31321 gcatgaaaaa tgtattaagt gttgaaaaat ggaaaagtat tatgaaaaca aagataatat
    31381 tacaaaagca atagataata atgatattac aagattaaaa ttcaaaaact tagataaatt
    31441 tagacaaaat gaattaggat ttatattcca aaattttaat cttttatata ctttaatagc
    31501 ttatgaaaat atagcattga cattaacaat taaagggaaa acaatataaa tttgattcaa
    31561 aagcatcaag attattactt gagagttttg aaagtttaaa tcaagattta aaaacaacaa
    31621 ttttaatgct aactaatgat gcttttatag ctagttatac tcatagaaac ttatttataa
    31681 aatacagaaa aatatttata gagttagcaa gacgaactga ttcaataaaa gagtctttta
    31741 atagaataat tgaagaaata gctataatca gaggagatga taacaatgta ttctaaaata
    31801 gcgattaaaa atgttagaaa aagctttaag gattatagta tatatttttt aactttaaca
    31861 ttagtaattt gtattttcta tagttttaac tctatggaat ctcaaaaagc tttaatggaa
    31921 atgagtactt caaaaaagcc tgatttagaa atgtttaaga atatgatttc atatatatct
    31981 gtgttcgtat cagctatttt atgtacttta attctttata ttaataactt attaatcaaa
    32041 aaaagaaata agaaacttgg aatttatatg actttaggaa tgggaaaaat tgaaatgtcg
    32101 aaaatattag tttttgaaac tataatagtt ggaatagtct ctttggtaag tgggctaata
    32161 cttggattat tagtatctca agggttatta atactattat taaagttatt tgaatttaat
    32221 atgagtgaat atagctttgt aatatcaata ccagcaatta ttaaaactat tgtctatttt
    32281 ggaataatat ttttacttgt aatgatattt aatatctatt taatttctaa atacaaaatg
    32341 atagatttat taattgtgga aagaaaaaca gaggatataa aatttaaaaa tccatttgta
    32401 tatatgatta catttgtatc atgctttatt ttcttattta ctgtatataa cactacaaat
    32461 catatcataa ttaatctaat agatgataaa caattaaact ccaagtctaa aggtgtagaa
    32521 ataaatgaat ttacatatca agattggcaa caattttgtg atataaagta ttatggaaag
    32581 aaaggtttaa tatcaatgac tttaaaagaa tatatagaaa aatacaatta gaataaaata
    32641 aattttagag ggaaggcatt gccctctata tttttgtgtt ttctagaatt gagtaaattt
    32701 tgttactcta gcaaagtata aaagaaagaa tgctggtctt gagtatttta tattagtaat
    32761 tattagggaa taatatataa ttactacaaa aatgaaacat taatgaaatg taaatcaatt
    32821 taaaaaaatt aaataaaaaa ttacaataga gatataagaa aattaattta aaggagaaat
    32881 agaacatgaa gaatatatta agtgttgaaa aaatagaaaa atattatgga aacaaagata
    32941 atattacaaa agcaatagat aatataagct ttaaagttga tgaaggagaa tttgttggga
    33001 taatgggtcc aagtggtagt gggaagacaa cacttcttaa ctgtatatca acaatagaca
    33061 atgtaacaat aggtaaaata ataataaata ataatgatat tacaagatta aaatctaaaa
    33121 acttagataa gttcagacaa aatgaattag gatttatatt ccaagatttt aatcttttag
    33181 atactttaac agcttatgaa aatatagcat tggcattaac aattaaagga gaaaaaccat
    33241 ctaaaattga ttcaaaaata agagatgtag ctacatactt agaaatagaa aaagtgatag
    33301 ataaatatcc ttatcaaatg tcaggaggac aaaagcaaag agtagcatca gctagagcaa
    33361 tagttactaa tccatcattg attttggcag atgaacctac aggagcactt gactcaaaat
    33421 cagcaagatt attacttgag aggtttgaaa gtctaaatca agacttaaaa gcaacaattt
    33481 taatggtaac tcatgatgct tttacagcta gttatgccca tagaatccta tttataaaag
    33541 acggaaaaat atttacagaa ttagtaagag gagctgattc aagaaaagag ttttttaata
    33601 gaataattga agtaacaact ctaataggag gagatgataa cgatgtattc taaaatagca
    33661 attaaaaatg ttagaaaaag ctttaaggat tatagcatat attttttgac tttaacatta
    33721 gcaatttgta ttttctatag ttttaactct atagaatctc aaaaagcttt aatggaaatg
    33781 aatgcttcaa caaaatctca tgtagaaatg cttaagaata tgatttcata catgtctgta
    33841 tttgtatcag ttattttatg cagtttaatt ctttatgcta ataacttctt agtcaaaaaa
    33901 aggaataagg aacttggaat ttatatgact ttagggatgg aaaaagttaa aatatcgaaa
    33961 atattagttt ttgaaactat aatagttgga atagtttctt tagtaagtgg actaatactt
    34021 gggttattag tatctcaagg gttatcaata ttattattaa agttatttga atttaatatg
    34081 agtgaataca attttgtaat atcgatatca tcaattatta aaactattgt ctattttgga
    34141 ataatgtttt tacttgtgat gatattcaat acttatataa tttctaaata taaaataata
    34201 gatttattaa caataggaag aaaaacagag gatataaaat ttaaaagtcc atttgtatat
    34261 acaattacat ttatattatg cattatttcc ttaattattg catatagcat ggttttaaaa
    34321 gttggattaa atcctaaaaa tcctaagttt attatgtcaa tagtattagg tgtaattgga
    34381 actatattat tcttctatag tttagcaggc tttgcattat atattgttaa gaagaataag
    34441 aacatttact ttaagggatt aaacatattt gtagtaaagc aaataaatag taagattaat
    34501 acaaacttta tatcaatatc tattatttgt ttaatgttat ttttaacaat aggaatacta
    34561 tcaacagggt ttggttttaa atcagcttta aatgcaggac taaaaggtgc aactccattt
    34621 gatgcaagtg caaccatgat tgtacatgaa aaatgtaaag tgaagaatat aaaagaatct
    34681 tttgaaaagg ttggaattaa gtttaataaa ggtgataaag ttgcttacta tgatgaatat
    34741 ataaatggta ataaactttc agatgttatg caaggacaat attctggtag agtggacttt
    34801 gaagtagcat atataaaatc ttcacagtat aatgaaataa gaaagttacg aggtgaaaag
    34861 tcaataactt tatcaaaaga tgaagtatta ataacatcta atgctacaga ggtagtacct
    34921 tcgatagaag aatacatgaa aaataataaa attataaaaa tagataataa agcatataat
    34981 ataaaaaata aaaaagtaat aaaagataat ttaagaactg attttacaga aacaaatgct
    35041 cttactgtag ttgtaaatga caaattgtgt gatagcatgg agatatcttc aagtatagta
    35101 aatataaact tcgcttcaga taataatgaa aagtcacaag aaaattttga taaaaggcta
    35161 aaatcaaagt atagttctac aagtttttat gaagttggaa ctgtatcagg tggatcaaga
    35221 aatgctatgt ataatgataa taatggtatg acttctacaa tactatttgt tggaatctat
    35281 ttaggaatag tatttttaat aagtagtatg gcagtccttg cacttcagca attaagtgag
    35341 gctagtgata gtatagatag atatgtatcc ttaaaaaaac taggagcaag taaaaatagt
    35401 ataagtaaaa ctatatttac acaaactcta atgtacttta gcatacctgt tggactagct
    35461 ttagttcact cagtagtagg aatacaagtg gctaataatt ttatatcaag gcttaataag
    35521 ccagatatag gagcttcatc acttatgaca gtaggaattt taatgttagt atatgcagtg
    35581 tatttttata caacttatca agggtataaa aatatagtta taaaaaagct taattaatac
    35641 aactaactaa aatctgttta cagtaaaaat catactgtaa atagattttt tgaaaataaa
    35701 gggtgaaaaa ttaatggaaa aaataattat agtggaagat gaagaagtaa tcagagatga
    35761 attaaaaagc tttttagaga ggtatggata tgaagttatg gctcctactg aatttgataa
    35821 tatagtagag tttatattaa gtgaaaaacc taatttagta ttacttgata taaacttgcc
    35881 aatatatgat ggatattata tatgtagagt attacgtaaa gaatcgaata taccaataat
    35941 aattgtaaca agtagaaaca ctgatatgga tgaactaatg agcatgaatt taggagcaga
    36001 tgattttgtg acaaagccat ataaaacaca aatactttta gcaaggattg ttgcattgtt
    36061 aaaaagaagt ggattaaatt cgaatgtaaa taatacttta atatttaagg gtattgaatt
    36121 aaatttattt aatgcaacac tcagatataa agataaagaa atagagttaa ctaaaaatga
    36181 atttaaaata ctatcttatt tagtggagaa tcaaggttca atagtatcta gagattcatt
    36241 tatggagtat ctatggcaca caaattggtt tgtagacgat agaactctta ctgtcaatat
    36301 aacaaggcta cgtaaaaagc tagatgaaat aggcatagaa aatttgatag agacaagacg
    36361 tggtttaggg tatataatat catgagatta agagagtata taggtgataa agttgttttt
    36421 ctaggtacta atttaattat atttttaatt gcatcaggta tcatgcttta tagtaaaata
    36481 aatgtcgttt taatatttat gttattttgt atatggtttt taccattatt tacttatatg
    36541 ttaattgatt atttacaata taagaagtac tttaattcta tagataatat tttagatgct
    36601 ttagataaaa aatatttgtt gccagaagtt attgatgatg taaattttgt aactggagaa
    36661 aaaataaatg atattttaaa agtaataagt agaaacatgc acgaaaatat taaatattat
    36721 aatgataatc aagaagaata taaagaatat attgaaactt gggttcatga aataaaaacg
    36781 cctatagcat ctagtaaact tattatagaa aataatagta atgagattac taaaaagata
    36841 gatactcaac tagataaagt tgaaaatttt gtggaacaag tattatatta ttcaaaaatt
    36901 gataatgtaa ataaagatta tataataaaa aagctaaacc ttgaagaagt tgtaaatgaa
    36961 gttatcaaaa gaaactatag agactttata aacaaaaata taaaattaga acttggtgaa
    37021 attaataaga ctgtatatag tgactcgaaa tgggttgagt ttatattaaa tcaaattgtg
    37081 gtaaattcta taaaatatat aaagtcaaaa gatggtttaa taaaaataag tgcaaaaagg
    37141 gtagaaaact caatagtgtt aactatagaa gataatggag taggtataga agagagagat
    37201 attaataagg tatttgaaaa agggtttaca ggagagaatg gaagagtatt tggaaaaagt
    37261 actggaatag gattatatct atgtaaaaag ttatgtaata agttaggttt aggtttaata
    37321 ttagaatcaa aagtaaatgt tggtacagtc ataaaggtat cattccctat agattacaat
    37381 ttattttagt gtatagttat aaaaactgac aatttttagt tgtcagtttt ttgtatttat
    37441 ttaagaaagt taagaatgta agcataattg ataggttctt ttttttactt gattttcata
    37501 aaaacgtatt atatcattaa tttagtagta aaagctgaag ggaagtaatt ataatgaaat
    37561 tagatagtaa taatcattca gtcttcttat tgcattatca tttagttatg tgtataaaat
    37621 atagaagaaa agtaatagat gattctatat ctgatagact aaaagatata tttgtagata
    37681 ttgcaccaaa ttatggggtg gtgttgatag aatggaatca ttatgttgac catgttcact
    37741 tattattcaa agcaaagcct aatacagaaa tttccaagtt attaaatgcc tataaatctg
    37801 catcaagcag aaggataaag aatgagtttc caagtatccg caaatactta tggaaagaat
    37861 acttttggag taaaagttat tgtttagtaa caactggtgg tgcaacattg gaagatttgg
    37921 aacaatacat agaaaatcaa gaagaatagt gataatatgt taagagctta taagtacagg
    37981 tttatacaaa cagtgaataa aaggaatatt ttcctaagaa ttttggatgt aacggactta
    38041 tctatcaaag aaaattaact atcatagcta tactactaac caaaatagtt tgtcaacacg
    38101 ttactcaaaa gatattgtgc atatagaaat gggtatataa aactgcttaa attaaaatca
    38161 atgattagga taaaacaaca taggcaattt gatagagttg tactgtatct aaagcatcat
    38221 caaataaatg ttatatttct attagtttgc caacgtagtg actcagatgc taatcgtaag
    38281 tgttgggaac tatcctatta gcttggagat actaataaca atagctattt tgacaaagaa
    38341 gatgccactt caaacgttgt cgtaggtagt taagtgtata agtagttaat tgcatgtgaa
    38401 atcaaaattc actataattt tattaaaaag ttatacttgt taaagatggt ttaatataac
    38461 tttaataaga tatactttaa aaggtatatc ttattaaagt tttttagcca ctcataaaaa
    38521 ataagatatt ggagtgaaag agatgaaatt taaatcaaat gttttaaagc agtttttttt
    38581 aattgctatg gtaattttta tggtaggagg tcttataggg tgtagtaaaa gtgacaaaga
    38641 gaataaacaa gctagtactg gtaagaaatt agaattaaaa tatgctagtg gatttagtgt
    38701 tgaagattta gaagatggaa ttaaaaaagt aactgatgga gataatcgag aactgatttt
    38761 aatcccaaag aagattaaaa ttcctgaaaa atataaaaat gctaatatag ttagaacgcc
    38821 tgtggacaat gtattaatag catctacaac acaggcttgt tctctgagaa caatagatga
    38881 actggatagt ataaaagccg taacaacaga agagcagtac tggactatta aagaaattaa
    38941 agatttaatg aaagatggaa aaatacatta cgttggttca aatttagcac cagattatga
    39001 aaaaatagta gacttaaatc ctgacttaac tatagtgagt agtggtttat cagaggctga
    39061 tacaaaattt attgacaaat taaaagaatt agggcttaat tatgttgtag acaatgagta
    39121 taaagagcaa aatccatttg gaagaatgga gtggacaagt ttaatagctg cattttatga
    39181 taaagaagat atggctacta gtgaactaaa taaaactgta caaaaggtag aagaagtaag
    39241 taaaaaaata aaaaacaaag ctaaacctaa agttgtatgg gcatctgtat atgaaggaag
    39301 tgcttatata gctcctaaag attcatatgt ggataatatg ataaaaatgg ctggtggaat
    39361 aaatgcatgt gcttcaatag attcaaatga agggcgagta agtattgaac aattgcatga
    39421 agttgcaaaa gatgcagata tatttgtata ttcatcaagt tcagattatg caccaaattt
    39481 agattctata aaatctagtg cacctgtatt ggctgatttg gatgttgtaa aaaacggaaa
    39541 cctatgggtg tttgctccag attattatca atcagtagat aagacggacg aattaatagt
    39601 agatttagtt gagatgttcc acccaggtac tacaggtgaa aaaatcaaac attatataaa
    39661 ttatgataaa tagtacagag aggacacaaa aagataggtt ttatagattt tagttaatat
    39721 agctttgcta agaggagtat acaaatggat tttatcaata aaatgagaat aaggaataca
    39781 acaatattta tagtattaat tataagtatg atacttactt ttttagtgtg tgtagcattt
    39841 ggctctgtaa aaattgaatt taaagaagta atagatgttg tattaagagg tatggataat
    39901 acagaacatt ataaaataat atacaatata agaatcccta gagtacttgc aaccatggta
    39961 ggtggagcat gcctagcagt atcaggtatt ttattacaga tattttttaa aaacccaata
    40021 gttgaaccgt atatattagg agtatcttca ggttctactt tatcagtagc tctcatgatt
    40081 ttgggaggat acacattggg atttgagagt gtaaattcaa tgagtatatt tgtagcagct
    40141 tttataggag ctttaattgt aatgtctata gtcattttat ttgcaaataa ggtaaagaat
    40201 ataacaactc ttttaataat aggaattatg accggatatg tatgtagtgg tataacaaat
    40261 gtgttacaat catttgcaaa tagtgataaa ttaaaagaat ttactatgtg gtctatggga
    40321 agtttttctg gatttacatg ggaaaaggta gaaatactta taatagttgg tatattaggt
    40381 cttttgatga ctgtattcat aataaaacct ttaaatgctt ttttattagg agaagagtat
    40441 gcaaaaagta ttggcataaa tataagattt tttagagttt tgatagtatt tatatctagt
    40501 atattagcag caatagtatc agcatttgca ggacctatag ggtttattgg acttgcagtg
    40561 ccacaaattt caaaattgat atttaaaaca tcagataata gagttttgat accagtagta
    40621 atatttttag gcagtatagt tacagctctt tgtgatttaa tatcaagagt aattttatca
    40681 ccagtagaat taccaataag tacgataaca tctttattag gagctccaat tgtagtaatg
    40741 ttattggtga aaaggaagga tagggcttag acatgttgaa aactaataat ttaagtgtag
    40801 gatacaataa caaagttgtt ataagtaata taaatgtaga agtaaaaaat ggagaaatac
    40861 tatgtctttt gggaagtaat ggagctggaa aaactaccct attaaggtcc ttatctaaac
    40921 ttatatcacc aataaaaggt gaaatatatt tgaatggtgt aaacataaat tgtatatcaa
    40981 gaaaagcatt atcaaaaaaa atggctttag tacttacaaa tagattatta ggtgatttaa
    41041 tgactgtaca agatatagtc aatataggaa ggtatccata tacaggattt tttgggagtc
    41101 tatctaagaa agatttaata atggtagatg aagcattgga gtctgtagat gccttacatt
    41161 taaagaaaag atattttgat gaactaagtg atggagaaaa acaaaaggtg ttggttgcaa
    41221 gggctcttgt tcaagaacca gaaataatta tattagatga gcctacaact cacttggata
    41281 taaaacatag attggaactc ataaacatac tgaaaaaatt aagtaaagaa aagtcaatat
    41341 cagtaatact ttcattgcat gaaatagaca tagcattaaa aagttgtgat aaagttgctc
    41401 ttataaaaaa taataaagtc atagcttatg gtcagcctga agatgtagta gatgaggata
    41461 ttataaattc gctttatgaa ttggatgata aaaactttaa tagtctttta ggttcagtag
    41521 aaattagtaa taaatctaaa aatgaagttt ttataattgg tggtgggggt aaagcaacac
    41581 caatttatag agcttttact aaaaaaggta taggtctgta ttctggaata atacatgaaa
    41641 atgatattga ttatgaaatt ggtagaacta tggggataaa gatgtttaca gaaaatccat
    41701 ttgagcctat aagtgatgag agtttcgatt tggctattag aaatttaaat gattccaaga
    41761 ttataataga tacaggattt agtgtaggag agacaaataa gaggaatata gatattataa
    41821 aagaggcttt aaaattggat aaaaaagttt attcttttag aaatagagat gagagtaaga
    41881 agtattatga cagtttggat aataagatag aacatataga taaagtttct caaataatca
    41941 atagtgcaga tataaataat ttattataat ttatgaaata aaatgtactt atgtgttata
    42001 gaaaaaagag tatagattat aatttttttg aaattataat ctatactctt ttgttatttt
    42061 gtttatgtat ttatatattt ataaaacttt agcattttat agataaccaa tagcttcctc
    42121 tctagttaaa aaaaagtgaa tccctgtagt cgattctttc catctatttt cattaaaatc
    42181 ttcagctaca atcgtttctc ctactctata tataaaattt tcatcagcat atgcacgagc
    42241 acttttaaaa gattctttac catctacact agtaattgac agtacttttg ccttatcaca
    42301 tctacaagca tttgatgtag cagacactct ttttgcgtcg ctgggtatta ataattgtac
    42361 cattctaaaa ttaaaacatt ttttatagcc tataaatgct cctgtttcag gacaatacaa
    42421 tttaaaaaaa cgagtacttt catctgatat tactccattt aaagtagcat attctaaatt
    42481 ggaattttct aaattagctc ctctaatatc tgagttagat aagtcacaaa atctaaaact
    42541 tgcaccactt aagtctgcat tttttaatat agaatttttt aatgaacaat ccgaaagata
    42601 agaattatta aaaatagagt tttctaaatc tgctttttct aaatttaaat tgataaggtc
    42661 agaccacgaa aagtcaatat tacttaagca gtatcctctt aagtccatat tttctaatct
    42721 taattctttt aaatctgcct tttctccagc attattgttt ttaagccata aataatgttt
    42781 ctcaagtgtt ttttctaatt cttgtttaga aatagttttc attaaaatca ccttcataaa
    42841 tttattttta tatatgtagt agcaaaatag tcatatattt aattatataa caataaataa
    42901 aaaacttcta aataatatat aaaatatcat cttaaaagta cttttttcaa tatatcagaa
    42961 tatattttta agctatttag agataattaa aatttttaaa caggacataa taagcttgta
    43021 ttgttttata tttgagttga taaaaatttc tttaaataaa aataatgtca attataaagt
    43081 aataaaagtt tagatataaa aaaatttgtg tatatactat atgtagtata taatagataa
    43141 agcactgact atatgtagtg cttttgtttt tgaaaaatac ttattgcatt tctataatta
    43201 tagattaatt ttgggatttc aactgataag taccaaaaga aataataagc aaattaagtg
    43261 aaattatggc acaagattat gttaaaagga cggtaaataa tgaattggat agagcttaac
    43321 aatcaagtga taattaaaaa tgaacaaggc aagtaccaat tggaaaagga taaggaagcc
    43381 ttaagtagtt acatagaaga atttatacag ccaaagttga gaaaatttaa taacctagaa
    43441 gaaagattga agtatttaat agatgaaggt tattattcaa aagaagtaat aaatcagtat
    43501 agcatagatg ttattaaaaa tatatatgat atgattgata aacataagtt tgaatttcaa
    43561 tcatatatga gtgcaaataa gttttatcaa aattatgcat taaagagcaa tgatggaaag
    43621 gaaatattag aaacatataa tgataaagtg ttaattgtag ctttgacact aggaaatggc
    43681 aataaagatt tagctttaaa cttggcagat aaaatagtaa aacaagaatt tcaaccagct
    43741 acacctactt ttttaaatgc tggaagaaaa agggctggag aaatggtatc atgtttttta
    43801 ctatctgtag aagatagtac agaaggtata tcgtatgcta tatcttcatc aaatcactta
    43861 tcaaagattg gtggaggagt tgcactaaat ttatctaaac ttagagcatc tggcgaatct
    43921 atcaaagata tagaaggtgc agctggaggt gttgttggag tagctaaaat gttagaacaa
    43981 tcatttagtt actttaatca aatgggagct agacaaggtt ctggtgcggt gtaccttact
    44041 gtattccatc ctgattttga attgttgatg gatactaaaa agataaatgc agatgaaaaa
    44101 ataagacttg ctacattatc attaggagct ataataccag ataaatttat ggagttggca
    44161 gaaaaaaatg aagtagcata tgcattttat cctcatactg tgtataagaa atatggagtt
    44221 tctcttgatg agatagaaat ggatgagtgg tatgataaat tggttaatga tagtgatata
    44281 agaaaaaaag aaataaatcc taggcagatg ttgacaaaaa tagcacagat gcaacaagaa
    44341 agtggatatc catatgtagt gtacatagat acagctaata gagaacatac attaaaagat
    44401 gttggaatta ttaaaatgtc taacttatgt tgtgagatat ttcaatatca aacaccttca
    44461 gaaatagagg ggtatggagg aaaaaatgaa tggggacaag atataagttg taacctaggt
    44521 tctttaaaca tagctaatgt aatggataat aaaactatag aaagtacagt tgaaacagca
    44581 ataagagcac tgtcatttgt agcagatagc acagatataa aaccagtgcc aacggtaagc
    44641 aatagtaaca gcaagtctca ttctatagga ttaggagcta tgaatttaca tggatactta
    44701 gtaagagaaa atattttata tacttcagat gatgctatag atttttctaa tgtatttttt
    44761 gcaatggtta gatactattc aattaaagct tctatgaaaa tagccataga aagaaatcaa
    44821 acttttgaag gatttgataa atcagaatat gttaagggaa gaaatagcaa ggttttatca
    44881 aaatactatg aacaatctta tctacctaag tcagaaaagg taagagcatt atttgaaggg
    44941 atttatatac caacaaaaga agactggaca aaattattgg atgaagtaaa agaaaaaggg
    45001 atatataatg catatttaat ggcagtagca ccaactcaaa gcattagtta tgttcaaaat
    45061 gctacatcaa gtataatgcc aattactgag ccagtagaag taagaacata tggagactct
    45121 actacaatat atccaatgcc atttttaaca aatgataata tgttgtatta tcaatcagca
    45181 tacaggatgg atatgagaaa ggtcatagat ttagtggcaa cagttcaaaa ccatgttgac
    45241 caaggtatat caacaacact gtttgttaca gatgaaaaga caactagaga tatagctaga
    45301 cattacatat atgcctataa aaaaggtttg aaaagtttat attacacaag aacaaagatg
    45361 acaagagata ctcatgagtg tctagtgtgt tcagtatagg gagagaaata tatgacattt
    45421 aatttacata aaatacataa tgcagttaac tggaatagag aagaagatgg atttacacaa
    45481 gctttttggg aacaaaatgt aaaacaattt tggcttcctg aagaaatatc tgtttctaaa
    45541 gacataaagg tatggaatga actaagtaat aaagaaaagg aattatataa aaaagtattg
    45601 ggtggtttaa cattactgga tacaaaacag gggaataatg gaataccatc tatgatgagt
    45661 ttaacagaaa acctacaaag aaaagctgtc ttgtctttta tggggactat ggaagaaata
    45721 catgcaaaaa gttattcttc tatatttatg actctacttt ctaatttaga aatagatgaa
    45781 ttatttgaat ggatagaaac agaaccaaca ttacaaagaa aggctgattt agttttagct
    45841 caatacgaaa atactacaaa tcaagaggga ttatacctat caatggttac aagtgtattt
    45901 ttagagagtt tcttgtttta ttcaggattc ttttatccat tgtatctatc tggtcaagga
    45961 aagatggtag ctagtggaga aataatatcg cttattctta gagatgagtc tttacatggt
    46021 aagtatatag gattgctagc acaagaaata tacgattcat ttgataaaat ggataaggag
    46081 atgttagaag agaagatgta ttctatactt tatagcctta tggagaatga gatagagtat
    46141 acaaatgtta tatacagaga aagtgggctt gaaaaagagg ttgtgaactt tttaaaatac
    46201 aatgcgaata gagctttaga aaatctaggg tttgagaagc tatatactgt agatgctata
    46261 aatccaattg tattaaatgg tcttagcact gaaaccaaaa cacatgattt tttttcaact
    46321 aagggtaatg gataccaaaa aggagtgtat gaggaattag aggatgaaga ttttataata
    46381 taatttataa ttatgacaca ctgttgtcac ttttagcgtg ataatatcaa tgtataaaat
    46441 atatatggag gtatttttat gaaatatgaa tggagaaaaa gagataaaga gttatattta
    46501 cctaaaaaga atcctgtaat agttgaaata ccagaacaga aatttatcat gttaaaaggg
    46561 agtggagacc caaattctaa agaatttact gaagcaatag gagtacttta ttctttggca
    46621 tatgcaataa aaaccatgcc taaaaaagga attgtgccag aagggtattt tgactatacg
    46681 gtttttcctt tagaaggtat atgggataag ggagaaaaaa gtaaaggctt agatgtactt
    46741 attaaagaag atttaattta cactataatg atacgtcagc cagattttgt tacacaagac
    46801 ctgtgggata aagctactga tatagtaaag aagaaaaaac ctcataatct tcttgaaaaa
    46861 gttagatttg ggtctattaa tgaagggcta tgtgttcaaa tgcttcatat aggttcatat
    46921 gataatgaac cagaaagctt tgacattatg aacgaatttt gcaaaaaaaa taaacttata
    46981 agaaaatctt acacacatcg tgaaatttat ataagtgatg ctagaaaagt atcgcctgaa
    47041 tcattgaaga cggttttacg ttttgaagta gaaagggaag tataaatatt ttgaataatt
    47101 tataagagtt ataaaaagtg aagtctgttg agacttcatt ttttgatgca attttaaaat
    47161 taaatttgat gtttcataat attttaaaaa ctttctactt ttattagtgt gaataactgt
    47221 tgctattaaa taataata
//
LOCUS       DAEPXW010000020        47055 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.020, whole genome shotgun sequence.
ACCESSION   DAEPXW010000020 DAEPXW010000000
VERSION     DAEPXW010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47055
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.020"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(214..462)
                     /locus_tag="KRM55_001113"
     CDS             complement(214..462)
                     /locus_tag="KRM55_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1593365.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(493..954)
                     /locus_tag="KRM55_001114"
     CDS             complement(493..954)
                     /locus_tag="KRM55_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH1593366.1"
                     /translation="MKFGGVLLIVKDINKSKKFFEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQV"
     gene            complement(992..1825)
                     /locus_tag="KRM55_001115"
     CDS             complement(992..1825)
                     /locus_tag="KRM55_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593367.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(2099..2785)
                     /locus_tag="KRM55_001116"
     CDS             complement(2099..2785)
                     /locus_tag="KRM55_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593368.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(2800..5277)
                     /locus_tag="KRM55_001117"
     CDS             complement(2800..5277)
                     /locus_tag="KRM55_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1593369.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTTTISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSDK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(5496..6899)
                     /locus_tag="KRM55_001118"
     CDS             complement(5496..6899)
                     /locus_tag="KRM55_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1593370.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLKKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIIFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHVTLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            7392..8252
                     /locus_tag="KRM55_001119"
     CDS             7392..8252
                     /locus_tag="KRM55_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1593371.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(8491..9048)
                     /locus_tag="KRM55_001120"
     CDS             complement(8491..9048)
                     /locus_tag="KRM55_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1593372.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(9238..10125)
                     /locus_tag="KRM55_001121"
     CDS             complement(9238..10125)
                     /locus_tag="KRM55_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1593373.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            10244..11443
                     /locus_tag="KRM55_001122"
     CDS             10244..11443
                     /locus_tag="KRM55_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBH1593374.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(11637..14192)
                     /locus_tag="KRM55_001123"
     CDS             complement(11637..14192)
                     /locus_tag="KRM55_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1593375.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKN
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(14189..14875)
                     /locus_tag="KRM55_001124"
     CDS             complement(14189..14875)
                     /locus_tag="KRM55_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593376.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            complement(14952..15860)
                     /locus_tag="KRM55_001125"
     CDS             complement(14952..15860)
                     /locus_tag="KRM55_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1593377.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(15862..16533)
                     /locus_tag="KRM55_001126"
     CDS             complement(15862..16533)
                     /locus_tag="KRM55_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593378.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLISYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            16795..17859
                     /locus_tag="KRM55_001127"
     CDS             16795..17859
                     /locus_tag="KRM55_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBH1593379.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            18017..18703
                     /locus_tag="KRM55_001128"
     CDS             18017..18703
                     /locus_tag="KRM55_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593380.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     KFDLIILDINLPDKSGFELCNEIKGNYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            18693..19724
                     /locus_tag="KRM55_001129"
     CDS             18693..19724
                     /locus_tag="KRM55_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1593381.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLMTDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVLFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANFKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIRVATECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            19806..20471
                     /locus_tag="KRM55_001130"
     CDS             19806..20471
                     /locus_tag="KRM55_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593382.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKNFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            20484..22901
                     /locus_tag="KRM55_001131"
     CDS             20484..22901
                     /locus_tag="KRM55_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593383.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGII
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(23082..23873)
                     /locus_tag="KRM55_001132"
     CDS             complement(23082..23873)
                     /locus_tag="KRM55_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1593384.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(23906..24493)
                     /locus_tag="KRM55_001133"
     CDS             complement(23906..24493)
                     /locus_tag="KRM55_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1593385.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYSNSKSVSPYLLLPLSYIEFAQEETHLFKL
                     LFINDLDLMMEEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(24670..26061)
                     /locus_tag="KRM55_001134"
     CDS             complement(24670..26061)
                     /locus_tag="KRM55_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HBH1593386.1"
                     /translation="MERLARREQAHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(26251..27549)
                     /locus_tag="KRM55_001135"
     CDS             complement(26251..27549)
                     /locus_tag="KRM55_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBH1593387.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYESCLEALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(27908..28783)
                     /locus_tag="KRM55_001136"
     CDS             complement(27908..28783)
                     /locus_tag="KRM55_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBH1593388.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(28976..29662)
                     /locus_tag="KRM55_001137"
     CDS             complement(28976..29662)
                     /locus_tag="KRM55_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBH1593389.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(29711..30244)
                     /locus_tag="KRM55_001138"
     CDS             complement(29711..30244)
                     /locus_tag="KRM55_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH1593390.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDEITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(30288..30920)
                     /locus_tag="KRM55_001139"
     CDS             complement(30288..30920)
                     /locus_tag="KRM55_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBH1593391.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(31010..32089)
                     /locus_tag="KRM55_001140"
     CDS             complement(31010..32089)
                     /locus_tag="KRM55_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBH1593392.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(32222..33568)
                     /gene="pepV"
                     /locus_tag="KRM55_001141"
     CDS             complement(32222..33568)
                     /gene="pepV"
                     /locus_tag="KRM55_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBH1593393.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(33637..34917)
                     /locus_tag="KRM55_001142"
     CDS             complement(33637..34917)
                     /locus_tag="KRM55_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBH1593394.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(35044..35304)
                     /gene="hfq"
                     /locus_tag="KRM55_001143"
     CDS             complement(35044..35304)
                     /gene="hfq"
                     /locus_tag="KRM55_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBH1593395.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(35418..36353)
                     /gene="miaA"
                     /locus_tag="KRM55_001144"
     CDS             complement(35418..36353)
                     /gene="miaA"
                     /locus_tag="KRM55_001144"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBH1593396.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEKEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINKKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(36391..38358)
                     /gene="mutL"
                     /locus_tag="KRM55_001145"
     CDS             complement(36391..38358)
                     /gene="mutL"
                     /locus_tag="KRM55_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBH1593397.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(38369..41212)
                     /gene="mutS"
                     /locus_tag="KRM55_001146"
     CDS             complement(38369..41212)
                     /gene="mutS"
                     /locus_tag="KRM55_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBH1593398.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(41373..42107)
                     /locus_tag="KRM55_001147"
     CDS             complement(41373..42107)
                     /locus_tag="KRM55_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593399.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(42076..43089)
                     /locus_tag="KRM55_001148"
     CDS             complement(42076..43089)
                     /locus_tag="KRM55_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1593400.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(43111..43881)
                     /locus_tag="KRM55_001149"
     CDS             complement(43111..43881)
                     /locus_tag="KRM55_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593401.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(43856..44146)
                     /locus_tag="KRM55_001150"
     CDS             complement(43856..44146)
                     /locus_tag="KRM55_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBH1593402.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(44277..44376)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      44996..45085
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            45138..45314
                     /locus_tag="KRM55_001151"
     CDS             45138..45314
                     /locus_tag="KRM55_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593403.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(45429..45785)
                     /locus_tag="KRM55_001152"
     CDS             complement(45429..45785)
                     /locus_tag="KRM55_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593404.1"
                     /translation="MDIDNNFEEFSNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPAIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            46094..46953
                     /locus_tag="KRM55_001153"
                     /pseudo
     CDS             46094..46953
                     /locus_tag="KRM55_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435256.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
BASE COUNT        16114 a         7300 c         5399 g        18242 t
ORIGIN      
        1 aacacatttg ataatgtcca attcatatat gcaaaattta tatactttaa aatatctaag
       61 aaattattca ataaaaaaat actatttttt aaaaattatc attattgata aagctctact
      121 atttatattt tttagtgtgt tcatgtataa taagtaaaag cacaacggta tatactgttg
      181 tgcttttttg taattaataa acaatatttt ggtctataac aatgaaaaat ggctactttc
      241 cataattgat ttcatctgac ataagcaaaa agggtgtcca gctgggtcaa tcataactct
      301 ccagtcatca gtaaattgct cctctgcgat tgtagctcca caatgaattg catattgaac
      361 tgcttcttct aaatcattaa cagcgaaatc catatgagcc atttgctgtt gagattcagg
      421 tttttctggt tctattatgc cccaagcctt tgttttttgc aatataaaga aaaaattata
      481 tattttaata ttttatactt gttgaaattg tgtaataaat tcaactggat acatagtgcg
      541 ttttgaaatt tcttctaaag ctaaaccttg ttttaaaagc ctctttatga cgctttccat
      601 actttctgaa atttctataa tatttttatc aaaatcataa aacctaaaag ttctttgacc
      661 ccatgggtat tcttttatat aatgcaaaaa ttcaatattt cctattctat ttatcttact
      721 ttcccattgt ttgatgtcat taacctcaaa atacaactga aagttatttg attgttgata
      781 tattggtaaa tcatatccaa ttatagcttt ataattactt tgtaatccaa atccattttc
      841 aaatgataca tgttctccta aatctaatgt gattttttgc tccataacat cttcaaaaaa
      901 cttttttgat ttatttatgt ctttgacaat tagcaatact cctccaaatt tcattttatc
      961 actatccttt ctttgttata agtattataa cttaaaattt tgcaatttca ctgtaaaaat
     1021 cagacatatt agctcggtat ttttgaggag ttattccaca gacaatttta aaatctttaa
     1081 taaaatgtgg tatatcatag aatcctaatt cattacatat agacatcaat gaagttttat
     1141 tattgtttag aagttttata gatttattaa tacgtaccaa acgagaaaat gacttcatac
     1201 tcaaccctag atactgatta aagagtctgt ttaaatgcct agaactataa aatacttttt
     1261 tagaaatttc ttgtgaagat atatttccag agttttgaat aatcaactga attgccaaaa
     1321 taaactcata tgagtattca attttaatat tagaaatcaa taattcttcc aactttaaaa
     1381 tcaatttatc tatagataaa gattcattaa atattttttt aatttctaaa tctaatgaag
     1441 tattaattat agaaaatgga acaactttat caataagttc actttgctgt atacctataa
     1501 gcgggaaaaa accagcaggt tgaaattcta taattagtat aacatcacat ctattagcaa
     1561 tatttcctac tgtttttggt ttagtagttg gaccaaataa tagactatgt aaccctgtgg
     1621 catcataaaa aaacaccaaa gttacacttc catgaggaat aatcgtgtaa ttatcagaaa
     1681 ttattgtttg atttggaaac gatatagtaa aattcgatat ccaatttctt aattgtatac
     1741 aaggcaagag ataaacaaaa ttgtcttcac aaactataag tgacctattt ttatttataa
     1801 aatgaatact ttcttttttt aacatatatt atatcctgtc ctatcgtgaa tatttattaa
     1861 agtaagaaga atccatatta tctctatata tcattaactg cttttaataa tagagatagt
     1921 atgaatactc attagatatt taataaacaa ataaaattaa aataatcaat aaaaaatata
     1981 gtacttttat ctgttatttt aatattatag cacatttata gtatttaact tatatccgct
     2041 ttacatatgt ctaatttata taattaaaaa tgcttatctc aaatacaata attactcctt
     2101 atacaattaa accatctgaa actgtaatag tacgactact acttttggct gcttctggtg
     2161 agtgagttac cataattata gtttgtccat tgtctctgtt tattttattc agtaaatcta
     2221 ttatttctat ccctgtttta ctatctaaat ttccagtagg ctcatcagca aataaaatct
     2281 ctggttttcc aattaaagct cgagctatag caacacgttg ttgctgacca ccagataact
     2341 ctcgtggtgt atgtttacgt ctatcagtta aaccaactat atctaagatt tcatctaatt
     2401 gatttttata atcttttaaa tttttaccat ctaataacaa aggaagcatt atattttcct
     2461 ccacatttaa atttggtatt aagttataaa attgaaatac gaatcctata tttctacgac
     2521 gtattatgct cattttctca tcattaaagt gtgatatatc agctccattc atatacactt
     2581 ttccgctcgt tggagtatct aaaccaccta aaatatataa aagagtactt ttaccagaac
     2641 cagattgacc catgatagaa acaaattcac ctttcattac ttgtaaagat acctctttta
     2701 acactcgagt tgttgtattt ccaattttat attctttgat aatatttttt gcttctacag
     2761 ctaaactatt atgtgtaatt ttcatattaa cctccataat tattcaaact taatttcttc
     2821 tatcagtttc attttcttcc cttttataat aggcactatc gaacctatta aagttactat
     2881 aattcccaat aacccaacaa taataaatgt tttaaaatct aaatctggtt tcattgaaat
     2941 ttttggtcct gcaactataa agatagtttg aatctcaagt atagatatca caataccaat
     3001 aacagctcca agtaaacctg aagtaaaccc ttcaatcaat gttactttta tattttgttt
     3061 atcacttagt cctatagatt tatacatagc tatagaacgt cttttttgaa tataattaat
     3121 cagtagatta ttaataatac ctactgtagc aagaagaaaa atgaaatagg tcatcttatt
     3181 cataggagac aaaaaactac ttatagtatt taaagaatca ttattaaatt cttcaactgt
     3241 acgactccaa ttatatgtat ctccaaataa atatcttatc tgaatcataa cagcatctgg
     3301 attgactgct gtatatacta aaaaaccata attagtttta tcaaaatcat taactgcata
     3361 atgtgatggt ataacagctt ctacatcatt tgcacgggat ttaaaactac ctactatttt
     3421 ataagaaaaa tcatacttat cattagatag agttattgta tctcctatag ataagcctac
     3481 tttttttaga gtatcttcat tcaaaataac agaacgttta tcattaaaag cttctattac
     3541 ttgttttttt atctcaaaat ttgtataatt gattccaaac atagagttat atagttttat
     3601 attatctgta ccctctagtc ttgataatgt tacaccatta ccagaaatct cattattcat
     3661 aacataaaga ggtaatattt ttttaattcc atccatatgt ctaacatctt caataaactc
     3721 ttcattcatc tttccatctg caaaaccttg taattctgcg tcacgaaaca catctgttat
     3781 ataagtttta acaaagttac caacaacact tattgcaata actgcagaaa tacttataaa
     3841 tagtaaagtg atattctgta ttatattttt gttatttttc atatttctag cagctaattt
     3901 accctcattc cctaaaatat ttttataaac aaactcaaaa actatagaca tgatatcagt
     3961 aataagagga atcaacacaa tagtagctac aattaatcct agtaatgaaa atccaccagc
     4021 tagatacaat gtattttcag gggatattct tggaagtaaa atagataaaa taaacattat
     4081 acttcctata aaaagtatag aacgatttga aacattcttt tcttctactg ttcctagtac
     4141 aatatttttt atcggcaaat ggctagcttt tttaacaggt atatatgcac taaatgaaga
     4201 aacgattatt gctactataa cagatataat cactccaatg ggtgatatta ctactggaat
     4261 tgatattcct tgctcgagag aatttcctaa cccatgaagc attaaattta aaacaactac
     4321 accaatagga atagcaatta atcctcctat acttccgtat aatatacttt caagcatcaa
     4381 tatacgagtt acagtttttt cattggcacc aatacttcta aatgttccaa taaaaggaag
     4441 acgttctaat gtaataacct tataactgct gtatattata aatatactaa gggttaatgc
     4501 aaaaaaactt attaaaaaga aaggcattgt cttttgtcta gcatctgaaa ttatcttagt
     4561 ttcatttata gtatttgata ccatatattt ttcagtagaa agttcttcgg ataatttatt
     4621 tactagattt tctgtaattt cttcttctga ctctataaga actcttgtat atccactgcc
     4681 tttatttata atttttgata gagtctcttt gggtagcagt gcatttacac ctcttgtgtt
     4741 cctcaaaaat actgtatcat aagatgcaat atcactaact tgaaaagtat aagactttcc
     4801 ataaatctgc aaagtaatag aatcaccttt ttttatttta tattttgatg taaagcgatt
     4861 tggaagaata attttatcac cagaaaaatc agtaatacta tcgccatttt ctaatcgtgg
     4921 cttgttgatt ttatttagtt gacttaagtc tgctgatata agactaaatt cttcatagta
     4981 tcccccttta ttataaatag cagagctttc caatacacca acctttgatt ttatagcatt
     5041 taaatcaggt atgtcttcta aattggttaa tatatctgga tttttacttt ggacagatat
     5101 agtcgttgta ccatacatac cttttgccat ttttctttgt gcactttcat aagataatcc
     5161 aattgagaat gaaacaaaaa gtaaaactgt tgataaaact atggacaata acataactgc
     5221 tgttctaatt tttcgttctt taatatttgt gaaaatatac tttaatataa ttttcaaatt
     5281 tacaccttct ttccttatct aagatatttc aatctaatat ttttatactt taatctaaat
     5341 taaatctcta atagactcct ccatactttt atcattctat ttataatatt tttaatcaaa
     5401 tcacccctta aataaaaaag attgataaac tactatataa atataataat ctatcaacct
     5461 taatatattt tttatttaac cttaattaac cttaattaaa taggaaaggt gatataaaat
     5521 gagctaccta atccaggtat actttcaaca gatatattcc ctccatgaac ttcaataatt
     5581 tgcttcgtta ttgctagtcc taaaccagtt ccttctattt tttgttttgt attgcttcct
     5641 ctataataac gattaaacaa atttgatgct tcttctcttg acatcccttt tccattatca
     5701 gatataatga tttcaattct ttcatttaat gttacatgta cacaaacttt agtattttta
     5761 tctccatatg taaaagcatt gacaataaga ttactaaaag ctcgttttaa tagtgtacaa
     5821 tcaaaatcaa agttaatatt atctatatta ctcttaaatt caactatatt tgattcatat
     5881 tctggataat ttaaaatatc aatggataat tctttcaaga atcttactaa atcataatta
     5941 tttttattta aagggattat tccatttttt aattgatagg ttaattttaa atcgtttata
     6001 agtgtatttg tatattctat attctttaac atgattgaag catatttata tactttttca
     6061 ggtgaataat tagtactact atctgtaaga agctctgcat acccttttat tggtgaaagt
     6121 ggagttttta aatcatgagt tatatttgaa atccactctt ctctcataat atcagtttta
     6181 ttttgtatct catcacttct atgaatttct tcatttaaaa tatttaaact attatatata
     6241 tcagcaaaaa cacctttaat attaactgga agatagcttc gttttgaaat atcgctaaca
     6301 gcagatgtaa tatttgatat gcactttgtt acccagtaac cataagcaat tccagaaacc
     6361 aaaattatta aaaatataat ccctatgatt gaaaatataa ttgacttacc acctataaat
     6421 ttacctccat caaaaaacat attcacttta gatatattta atggaaaata tataatataa
     6481 atatagtcat ttttattatt tttaattgta ttaaagtata cagttccatt acttgaatta
     6541 ttttggttag ctaatgctaa taattcagaa ttagaataat aatctttatg ctcttttggt
     6601 tctaaaaacc cataaactct atttccacta gaatctaaaa tttgcaacca caattgattt
     6661 tctcgaagtt tttttaatcc agactgtttt acttgtggct tattatctat aaatacgatt
     6721 tgttcattaa agttttctgt aaattttttc ggccagtcac tacgaataaa ttccccattt
     6781 ggtttctgaa tagtaataag tgataagaaa atacctatta ctgtcaggat taagcaaata
     6841 aaaatcatga aaaaaataat gtatgaatga aatactgttt tataactagg tttatgcatt
     6901 taatcaactc ttttcttaaa cttttatttt gattgttgct tatataaaat agacaataat
     6961 tattgatatg taaaaattta tttaaaaata caactatcta cataaattat atttatataa
     7021 ttatatgtta tcaagctgtc tgttgtattt aataaatcat tttgataaca tataaaagta
     7081 agataaattt ttccattaaa taccttataa ttatacacaa aatctctata tacgttaaac
     7141 agtatagaga aaattttcat agaaccatct ttatagggga tactttataa aagaataaaa
     7201 aaattataat atataaaaac ttcataggag tgtaacaaca tcagtaaaaa tatgaaaaca
     7261 ctatataaaa attcaaaaat attaagaata atgaaatact tgaaattgct tatatcaaga
     7321 aattttatat aatataaact ggtcaaatat gttataatat taaattgtga caagttcatg
     7381 gaggtgttta tatgaaaaaa caaaagtcgc caattttact tgaaatgctt ggactatttt
     7441 ttggttgtat atcaatgagt attggtataa atatgttttt aaaaccacat acaattgctc
     7501 ctggaggact tagtggtcta tcattagtac taaacaaggt tacaggactt ccagtatcag
     7561 ctatcatgtt aattataggt gtcccattag taatacttgc ttttagaatt atgggtacaa
     7621 aaaattcatt aaaaacttta tttggaacag ttgtattttc agctatagtt caattaacag
     7681 acccattatc aaaactaaga tttactaatg acttattatt gtcttctatt gcaggaggaa
     7741 tcctagttgg tataggttta ggaataatgt ttaaatcaga tgcttctact ggaggaacag
     7801 acttaattgc actcatactt agtaagaaat tcccaggaat aaaagctaca aaattcatgt
     7861 catgcctaga tggaatggtt gttatatctt ctggtatagt aaatcgtagt ttagaaactg
     7921 ctctttactc tggtatagca ctttgtgtat taataaaaat agcagatatg ataatggaag
     7981 gatttgacca ttcaaaagca ttttttatta tctctgatga gcctgaaagt ttaagacaag
     8041 ctataactga agaacttgat agaggtctta ctattcttga tggtaaaggt ggatatacta
     8101 gagaaaataa agaagttcta ttagtcgtag tttctaaaaa acaagaactt tatctaaaga
     8161 gattagttaa aagaactgac cctactgcat ttgttattgt tacagatgta catgaggttc
     8221 ttggagaagg atttaaaaat ttagagaact aataaaaatt aatattttaa gtatatatac
     8281 tattttaatt aaaatacgat ttattcaaaa agagtgtctc ataaactttt tagttcatga
     8341 gacattcttt tttgtataaa atcaaatgca ttttcagtat tttaacaata aaaacaggat
     8401 tatctatatt ttgaggcaac cactttattg aaattttatt tagaaaacaa tcattactaa
     8461 ataaccagca tagatattaa atgattatat ctattgtttt ttcaattcat attgataaca
     8521 aggaacattt tttacagtat ttccagtatg aatttttttg atatactttc ctgtacattt
     8581 aaatcctaat aaatctaatg attttgtaga attttggttt tcttcatagg ttattgcaat
     8641 tattttattt aagtttagtt ctctaaatcc atactgtatt actctttttg ttatctcagt
     8701 agcaaaatca tgtccccaat agcttggatt tatacatata cctatttctg cttctaatgc
     8761 tttaggattt atattattaa accccatatt tccaataact ttattgtctc ttttatatac
     8821 tatagcaaag tggccaattt tccctttttt atatggattt agaaaaaatg attttataaa
     8881 ctttcttgta tcttctaaag atttatgctc actaaatggt aaatgtttta ctactatttt
     8941 atttttataa cagtcaaaaa aatcttcaac atcatctaat gatgcaggtc ttagtataca
     9001 acttctagtt tctaaggttt tcatttgagg atattcagaa tcagacattt ctaatccccc
     9061 tttatacatt aatctaaata tactgttcat atttaaaata cgatattaat tatataaatg
     9121 ttctcaaatt aaccttattt ttatttttaa taaaaactaa ttactatatg aatctttcaa
     9181 atttacgaat ttatctctat ttttatatta aattacttgt gaaatatgta ttctaaatta
     9241 tatattatta gatatcatgc ttaaaaattc tttggttgct aaggataaag atatatcttt
     9301 taaatggcag taacctatat ttctcttagg tattggctct tttatatcta atttaaacaa
     9361 tttctcattt tccaaataat ctatgctaaa ttcttctata acacaagaca ctccaagatt
     9421 tatatacgca aattctaaaa gtaattcatg agaacccaat tctatatccg ggtttagttt
     9481 tatacctttt gataaaaaat attcatttac ataaagtctt gaatttgctt tattttctag
     9541 cattattaaa ggcaatgtgt ttaattcttc caatgatatt ttcctacctt tgtattctat
     9601 gtaatcattt gcacatacaa atatatcatg tatttcaata cactcaacaa tatttagtgt
     9661 atcatcttct attggcatgt ttataattgc tatatctata ttcccatctt tgagtaaaga
     9721 tataagttct ctactcgttc tatttattgt agatacatgt atatgtggat acttcttatg
     9781 aaaaatttct aaatatttta acaagaaaaa acgtgcagct gtatctccta ctcctatttt
     9841 cagagaaccg tattctaatt ttttaaattt atttattcta tcttctcctg atgatattaa
     9901 ctttaatgca gtagtgacat gttcacttag aattttcccc tctggagtta attttactcc
     9961 cttattgttt ctataaaata ataaagtatc taattgttct tctaattgct ttattgactg
    10021 gcttacagct ggctgtgaca taaacaattc cttagcagca agagaaaagc tcttattatt
    10081 tacaactgca ttaaaaacct tataaagttc aagttttata ttcatatata attactcctt
    10141 atgtcaaata ttagtattat ttattttact tataattata tttgaattat aatatacatg
    10201 gtactaatat gacaatatta attctttagg aggattttag ataatggata gattagttgg
    10261 aactgtttca agaggggtta gagcacctat tataagacaa ggagatgact tagttaaaat
    10321 agttgttgat tctgttttaa atgcgtcaaa aagtgaaaac tttgaagtta gggacaaaga
    10381 tgtaattgcc gttacagaag ctgttgtagc tagagcacag ggaaattatg ctcacgttga
    10441 caatattgca aaagatgtaa aagataaatt tggagatgat actgttgggg ttatattccc
    10501 aattttaagt agaaatcgtt ttgctatatg tttaaaagga attgcaaaag gatgtagaaa
    10561 agtcgtatta atgttaagct acccttctga tgaagttgga aatcacttaa taagtattga
    10621 tgaacttgat gataagggaa taaatccttg gtcagatgtt ttaacagaag aaaaatacag
    10681 agaactattt ggatataaca agcatacatt tactggtgta gattatgttg attattataa
    10741 gaatttaatc aaggattgtg gtgcagaggt agaaatagta tttgcaaaca atccaaaaac
    10801 tattcttaac tatacaacaa gtattttaac ttgtgatata catacaagac aaagaacaaa
    10861 gagaatttta agacaaaatg gagctaaaaa agtatattca cttgatgata taatgacagc
    10921 aagtgtagat ggtagtggtt acaatgacca gtatggactt ttaggttcaa acaaagctac
    10981 agaagaaaca gtaaaattat tccctataaa ttgtgatgaa gttgtaaaca aaatccaagg
    11041 taatataaaa gaaataacag ggaaagatgt agaagtaatg gtttatggag atggagcttt
    11101 taaagaccct gtaggtaaaa tatgggaatt agctgaccca gtagtatctc ctgcttatac
    11161 aaaagggcta gagggaactc caaacgaagt aaaattaaaa tacttagcag ataatgattt
    11221 tgctgactta tctggtgatg agttaaaaga agcaatttca aaatacatag ttgaaaaaga
    11281 taataaatct gatgatttaa caggaaacat ggtttctcaa ggtactactc caagaagatt
    11341 aacagacctt ataggttctt tagcagattt aacatctgga agtggagata agggtactcc
    11401 tattatttac atacaaggat atttcgataa ctatacaaaa tagtatgttt taataagatt
    11461 taaatttttt ggattatata tattaacatg aaaatttatt aaaacctctt aatagatatg
    11521 acttttcaag agttatatct attaagaggt ttatttaatg ttcacagata agatatattt
    11581 aaataattta aacaagattg tcagaaagtt atataatctt aaaaatttat ataactctaa
    11641 ttcttattta tttctgaaat aatatcactc ttcaaaattt gtcttactgg aataattaca
    11701 gcaactatac taatagtgat atttaaaata atcataccta tgtatagagg tgtatttatt
    11761 ttaagaattg gatttatata taaatataca cgttttacca taaaataaat cataaattgt
    11821 ccaataacac ttccaattac cattataata cttgcataga atccatataa aaaaccttct
    11881 cttatcatca taagtaaaaa cttattatcc gtaataccca tagctcttaa aattccaaac
    11941 tcatgtcttc ttgaaaaaat taagtagctt actgtattga ttatatggaa caaacttatt
    12001 gcaagaagta caaatacaat accatatata aataagagtt tttgatttaa gtaggtatta
    12061 tttttttcaa tagcaatggt ataatctgtt acgatacatc tttttacatc acttacaaca
    12121 ctttttatgt tctcagacaa ttcctcactg ttactatctt ctgtcttttt tatacttact
    12181 gaattataat tttcgatatc aaagttattt ttcatttgcc cattcgtcat aactatatcc
    12241 ataccataat caccaatgaa atatatgtta tttgccatca cacgttttac agtagcagca
    12301 actacaaatt cttttgttgt ataatcattc ttattttctt ctttaaattt aacaatttca
    12361 tctgttggtt tcattgtctt tggcacttta acttttattg tatctcctgg atttatatca
    12421 actgcatcat acatcccagt tccatccata ggtagtctaa ctataacctt attattttta
    12481 accatatcat gggtattaat ctccccatct ataatataag aatttaatcc ttctaacata
    12541 ccattgttat aaccataaat atttgttttt aaaagatagc caccttcatt ttgctttgta
    12601 caaataccat caaaaaaagt ctttatcctg taatcttttt caagaggttt aaagaaattt
    12661 ttccaaaata gttgttcttc tttaatttgc atagctccaa ataaatatct tactggatag
    12721 acttttgata ttccctcaac attgtttaat cttgaaattt tatcttttgg tatacctaca
    12781 tcaaaatctg ttgtttgcat agttatttgg tagtcagaat ttaaaccatc atcagctttc
    12841 attgtaagtt cattattatt tttagtaagc tgtatagagt aactagaaca tagaaatata
    12901 attccaccaa gtgataatga aaacaaaatt ccaataaaca ttcccttttt ttgagtcatg
    12961 tatttatgag ataatacttt tgtcatgtta gagtgtttta cactttctaa tattctattt
    13021 ttcttattag taatcttaaa gtttttcata gattctatac tagaatattt attcaactga
    13081 tgtacaacac gtacagcaat taaaattaac aacaataaga taaataaaaa gcctaaataa
    13141 atagattttt cacttataaa aaatgctcct ggaacaatat cactactcaa aaatatatgt
    13201 ggaaattgtt catatattgt agacgctact ccaataccta agaagcaacc tataggaaat
    13261 ccaacaataa aaagtaaaaa taactctaaa aatagtagaa ataaaagttg tttattatta
    13321 gcgcctaata cttctaaaac cccatattgt gatattctct gaagtattga aacatggaaa
    13381 atactatata ctgctgctgc accaaacact ccaacaagca atataattgc atttgtattt
    13441 agttctaaat tttttaagaa ctcaaatata ttatattttt ctatattttt tggtggtttt
    13501 actccaaatt caactgaaag aggccagttt atataagttt tttcttttga tatgttgaat
    13561 tttttcataa atttataatt ttgcttttta atatttttat tttcatcata ttttacataa
    13621 actatataag aatccttttc tttaggctga aaataatcgt ttacaaatcc ctccagagca
    13681 gtttctgggt ttgaaagact tgataaaata ccacataact tatagatttt accatctaaa
    13741 ttgatttctg ttccaatttc tttgtttaca tttaaattgt ttagagaata tgtgtcaagt
    13801 actatctctc catctttact aggaagagtt ccttttaata attttctacc tgtcatgtct
    13861 aaatatgaag aatcagcatt taaaaattct ataataaaag gttcatctat ctgattttta
    13921 ggttttgtaa cgccaagtct atctacagtg tattcctttg attttttatt ttttttaatt
    13981 ttattaagtt gttccttatc tactttatag aaataatgat aatctccact atcttccctt
    14041 atcttttcaa ttctactttt gtctgcacta tgaactaaag aaccaattcc cgtcaataat
    14101 gctactgata gtactatact taaaactata gatatagatt gttttttata atgctttata
    14161 tattgaattg aaaattttac tagagacatc atagtacttc accaccagta ttcaccacaa
    14221 ctccatcttc aatatggata attgagtcgc atacttgtgc tatattttca ttgtgtgtta
    14281 ccataagtat cgtttgatgg aattttgcac tactttcttt taataaacat actacttcca
    14341 ttgtagtttt actatcgaga tttcctgttg gttcatctgc taatataagc gcaggtttat
    14401 ttgccaaagc tctagcaatt gctaccctct gttgttgacc accagatagt tcgcttggaa
    14461 attttaaacg cttatcccaa attcccaatg tcttcatcag catttcaata tattcatggt
    14521 ctatatggtt tcctttatct aatgtaacag gaagagctat attatcataa gtgtttaata
    14581 cgggcattaa actgtagttt tgaaatataa atcctatatt tcttcttcta aatactgtca
    14641 aatctttttt tcctatttta gatatgttct ttcctttaat tattacatca cctgaggttg
    14701 gattatctaa tccacctata atatttaaca atgtgctttt tccagaacca gaagttccaa
    14761 ctatagcagt aaatgtatct cgttcaattt ctatacttac tccatttaag gcttttactt
    14821 tagtctcacc ttttccatag tgttttacta aattattcgt cactaatata ctcatttaat
    14881 ttctcctttc aatacagata tatgttctat aaaatattgt aagtgacgat aattacactc
    14941 atcctacaaa attagtttaa actcttacaa ttctgtaaga agatactaaa acaacatcca
    15001 cttcctagtt tagattctac tataatgttt ccattttctt tttctaaaat taatcttgta
    15061 agatatagac caatccctgt gccattttgg ttttccacat ttttacttct gtaaaatctt
    15121 ttaaaaatat catttagttc tctactatca atacctattc cctcatcttt aatagtaatc
    15181 ttcgtatata gttccatttt tattacagaa atagtaatcg tgctatctga tggtgagtat
    15241 tttattgcat tttctaaaac atttacaatt gcttctatgg tccacttttt attatgaact
    15301 aactttatgt ctgaaaatgg ttcgagattt atccttatat ttttagcttc tgctttatta
    15361 aagatagtac tgatactttg aataagagta tctttaatta gtagttcttc tacttcaaat
    15421 tctataactc catcctctaa tttagtcatt ttaaataagg attgtaacag ccagtcaatc
    15481 ttaaaagttt catttttcat cttttgtaaa aactccttct tctgtaatgt ggaaatattt
    15541 atattctcca gaagttcaca ataaatggtt atatttgaaa gtggagtttt taattgatgt
    15601 gacatatttg atattaaacc tttaatcgct tctttttctg actttgactg ttctacctct
    15661 atttctatca tatccttaat tttttttact tggtgagaaa tttttgacgc tcttgtatcc
    15721 tttgtatctg gataagtaac ttctttacct tccaatattt gatttaacat caaatttaat
    15781 tcatcatatc tttttcgatt tattttagta gatactataa atataacaac tgtacatatt
    15841 ataaaggcta atataaacat attattctac ctcattccat aaataaccca ttccataagc
    15901 tgtttttata tattttggat tagatgggtc atcctctact tttactctaa gtcttcttat
    15961 atttacagat acaatattat catcaacata attttcttcg ctgtcccaaa tatggtgtaa
    16021 aatttgttcc tttaataata tttgaccttt attttcaatt agataactta taagcttata
    16081 ttctacagag ctaagttcca aacattcttt atttttatat acttttagta acttttggtc
    16141 caattttatt ccattggaat atattacttt attattcgat ttttttctta ttgctacttt
    16201 gactcttgcc tttaatacag ataaagaaaa tggttttgta atataatcat caagccctat
    16261 ttctaatcct tttacttcat caatttctga gtctcttgca gtaagcatta taattggtat
    16321 atctgacttt tcccttatta tttgacatac atcaaatcca tctccatctg gaagattgca
    16381 gtctaagatt ataaaatcta tatttttact attaaatata tttaatcctt cttgttttgt
    16441 ataagcctta aatacattaa atccatcatt ctcaaatgca taaaaaagac cttcatttaa
    16501 gtttatatca tcttcaataa ttaataagtt caattttact ctcctttaga ttttttagat
    16561 aaataattat tttcttgcat tatcatacta aaaatatttt aattttattt atttcactaa
    16621 aaagattgta tttaaatttg ttttcaaaat aaaaacatca taatcaagca tatagttata
    16681 tatttcccaa tttaattacg cttaaattga aaatataact ttattcttat ataattaaat
    16741 tatacaacaa taaagttata ttttttaaat atatttttac tagggggaat agaattgaaa
    16801 agggttgatg agagaaatac tatgtttgca agagcaaatt acaaaaaaga tagtactgct
    16861 tataatgact attataagaa aaatcctgac aaaaaagaaa ttgatgatag tataagaaat
    16921 agaccaaatt tatgtagtga aggaacaatg acttacaatg agttaaactc tccaatggca
    16981 agtagtgcat tcgatttttt atctgatatc aaatctttat gcgaaggaaa agtttctgat
    17041 actaaagtag atgtagatgc aaagtcaatg acaaaaaaaa ttaagggtct tgcaaagcag
    17101 tatggagctt ctgtagttgg tataactaaa ttaaaagact atcatattta tacaaatagg
    17161 ggtagacatg aagaaaatta cggtgaagaa attaatctaa ctcataagta tgcaattgta
    17221 tttggatgtg agatggataa agaaatgata aatagagctc caatgatatg tgaagttata
    17281 gaaacatcaa agtgctatgt ggatgcatct atcgtcggca tgattttaag ttactatata
    17341 agaaatttag gatatgatgc tagaaatcat atggatgcta attatttggt aatgcctgtt
    17401 tttatagctc gtgatgctgg tttaggagat ataggaagaa atgctatact tacgaataaa
    17461 gattatggct ctagacttag attaggtgtt gttactacag atattcctct tttagaagat
    17521 gaatatgttg attttggact agaagatttt tgtaaggtct gtaaaaaatg ctcttttaac
    17581 tgcccttctc attcgctttc taatgatatt aaaattggtg atgatggaaa atataattgg
    17641 gtaattgaac atgagacatg ctatattaaa tggagatatt taggtacaga ttgtggtatg
    17701 tgtatatctg cttgcccatt tagccaaaat ctcgaaacta taaagaatac tacttcattt
    17761 aagggtaata atgagcttat tcaaaaagct ttagatgagt atacttcaaa atttggtaaa
    17821 agaatattta tacctggaaa tccatcttgg ttgaaataat tttatttaat aaagaatctg
    17881 tactagaatt tatcatagga caggttcttt attaaatata taaattttta aatacttttt
    17941 ctcgtttata acaattcagc aatgttttta gtctataatt gacattataa aatattaaac
    18001 taaaaggagt aactgtatgg aaaaaatatt agtagtagaa gatgattcta tattaaataa
    18061 aactctatca tataacctaa ttgaagatgg atatataatt acttcaaaat ttacagctaa
    18121 atctgcactg aagtctattt ttgaatgtaa atttgattta ataattttgg atattaattt
    18181 accagataaa agtgggtttg aattatgtaa tgaaataaag ggaaattaca atataccaat
    18241 aattttttta actgctaatg atatggaatg tgatatgatt aaaggctatg aacttggagc
    18301 tttggattat ataacaaaac catttaatat caatatattt aaacaaaaaa ttaaagcttt
    18361 tttaaatcat cttacaataa aaacaaaaca agattactat agggatggat atcttgaaat
    18421 taacttttct gagttatctg ccaatataaa tggaaatcaa attatattta caccattaga
    18481 atatcgtact ttaaaactgc ttactgaaaa tcctaaaagt attttaacaa ggaaagtact
    18541 tttagaaaaa ctctgggata tagatgctaa ctttgtagat gaacatactt taacatctgt
    18601 tataagtagg attagaagca aaattgaaaa agacaatctt aagtatatca aaacggtata
    18661 tggtatggga tatatgtggt taggtgaaag aaatgaattt taaaaagttt tcttttagtt
    18721 ctatttattt aataattgct gttggtataa tttttacagc tattttattt agtatctcaa
    18781 tttatctaat gactgatgat ttaaaactaa ttgctctatt attaatatat acaatagtac
    18841 tttgtggatt tatagcatta ataatatttt tacttcataa aaaaatagtt ttattttgtt
    18901 ctaaaatatg tcacacttta gatagtatga tgaatagtga agataatatt gaaattgaat
    18961 tagaagaaga aactatttta tcacgtatca atcacagatt aattagaatg tatgaagtta
    19021 ttcaagaaaa tcgcaatagt attgctatag agaaagctga tttacaagaa ctagtttctg
    19081 atatatctca tcaaattaaa actcctattg caaattttaa aatgattaat actactctac
    19141 taaatcaaac atttaaaaca gaaattcaaa aggatttttt aatggatatg gaaaaccaat
    19201 tagataaatt agatttttta atgcaatcta tggtaaaaac ctccagacta gagacaggta
    19261 taatcacact atctaaaaag aaaaattcaa tttatgaaac aattgctaca gcacttagtg
    19321 gaattttgtt tgatgctgaa aaaaagaata ttgaagttac agttgattgt gacccaaatt
    19381 tatatataat tcatgacaag aaatggactt ctgaagctat ttttaatata ttagataatg
    19441 ctgtaaaata cacaaattct aatggtaaga tacgtgtagc tacagaatgt tgggttatgt
    19501 atacaaaaat agatattatt gataatggaa aaggaatatc agaaagtcac caagcagaaa
    19561 tctttaaaag attttatcgt gaagaagatg tccatgacat agaaggtatt ggaataggtc
    19621 tctatctttc aagaaaaatt atatctcttc aaggtggcta tattaaagtt acatcagata
    19681 ttggaaaagg gtcgactttt tctattttct tacctaataa ataaattttt aaatatttca
    19741 tttgtaatga ttctgcaaca ttttggtttt atactgtatt tacaagatgt taaggaggta
    19801 ttattatgag tattttacaa gtaattaatt taaagaaata ttatggacaa agttcaaaca
    19861 ttacaaaagc tcttgatggt gtaactctat ctattgaaaa aggcgaattt atttctattg
    19921 taggtacatc tggtagtggc aaatccacat tattaaatat gatgggagga ttagataatc
    19981 ctacatctgg aaaggttatt ataaagggta aggaattatc tactatgact gatgaacagc
    20041 ttacaatctt tagacgcaga aatataggtt ttatatttca aaattataat cttgttcctt
    20101 tacttaatgt atatgaaaat attatcttac caataggatt ggatggagag accatagata
    20161 agaattttat aaatgaaatt ataaatatgc tttctcttga agaaaaatta tatgatatgc
    20221 caagtaatct ttctggtggt caacagcaac gtgttgctat agctagagca cttgtaacaa
    20281 aaccagctat tatactagct gatgaaccaa caggtaacct tgatagtaga actagttcag
    20341 atgtactgag tttacttaaa gtgacaagta aaaaattcaa ccaaacaatt gtaatgatta
    20401 cacacaataa tgaaattgca caactaactg atagaattat tcgtattgaa gatggaaaaa
    20461 ttgttaacta ggaggtgtag tatatgttta gaaataataa tcgcacattt ataagaaaaa
    20521 tagctttaaa tgatttaaaa attaataaac ttaaaacata tctttcaggt atcattataa
    20581 tgatttctac atgtttatta ttaacagtga ccttagtttc atataatgcc tctgtagatt
    20641 tagttaatgc atctccatat catgctatat ataaatctgt agatgaaaaa gcaaaaaata
    20701 tactatataa agataaaaac tttagtggcg taggaactta caaattaatt ggaagtaata
    20761 aaaagacaga ttgtattatg tcgattgttt atgcagatga tacagcaatt aaacttatga
    20821 attttcaacc attgaaaggc aaactaccta caaataaaaa tgaaattgct atttcagaaa
    20881 aatatttaca ggaatttggt ttagataaag atattggaga tagcattaaa ttaaattatt
    20941 atgatgatat tacgaataaa gaagttcaat gtgattttat tattgttgga tttctagaaa
    21001 attattatca agataatgcc aagcaatact atacagtcgt ttcaaatgat tattttaaga
    21061 atatagcttc tacaccttta caaaataaaa gtaatacttt tgacgagtca agacctgata
    21121 ctgtagatgt attagttaaa ctatcagaag aaaatacaga gaaagattca gcttcaatta
    21181 agacacagtt aaagaaaatt ggtttatctt taggtattaa gaaatataat atatacttaa
    21241 atgataacta tattgaatca aatttaattg atggtgagca gattattaca gttttagtag
    21301 ttggaatagt tgttcttttt tctagcgttt ttgttatata tagtattttt tatatttcag
    21361 ttgttaattc ggttcagatg tatgctaagt tgaaatcgtt aggtatgact tcttttcagt
    21421 taaaaaagat tatttctcta caaggaaata ttttgtcaat tatttttatt ccattaggga
    21481 ttatagcttc ttgtataatt gcttacataa ttcaaccatt agcatggcaa atgatagctg
    21541 atttatttat aattttaatt ttatcactgg taatgttttt aactgttaga atttctttat
    21601 ttaaaccagc tagaattatt tctaaaatat ctgctattga agccatgcaa tatacagaaa
    21661 ctaaatttag aaaaaaagca aaaaatttta gttatataaa tataaaaaat ctagcattaa
    21721 agaatatcga gtcaaataga aagaaaaatt tgattgcatt aatatcgcta agcattagtg
    21781 gagttttatt tatttcaatc gctaatcttg ctaattcaat agatttcaaa aaacaactat
    21841 ctcaacaatt tgtctataac gaagattata taattagcat taagagtgat aacttatatg
    21901 agcatattac agaaatccaa caaaataatc cactaacaga ttctcttaag aatgaaatta
    21961 aatctattca tggagtaaaa aaattaattg aatccaaatc aattaaaagt aatattatag
    22021 aaccttacat caaagataga gacgaaaaac aatttattac tctaattaaa ggtattacgc
    22081 ctgaactttc aaaatcactt gaagaatata ttgtcagtgg aaaaatagac tatacacatt
    22141 tagattcaga tagtttaatt ataaataaat atagaacaaa atattatgga ttaaatttaa
    22201 aagttggaga tacagttaca tttaatatct ttagtggaaa tgatattatt aaaaagaaaa
    22261 tgaaaattat aggaatcatt gacaattcca atacaggagg tatgtttttt gcttcagaca
    22321 aaactttaga atctctaaca ccatataata caaatttaga tttttctatt ttaatagata
    22381 aaaagcattc taaagaagtt gaagaaaagt tgttaagtat aattcagaaa aattcaaatt
    22441 taatgcttta ttcatatgaa gatgattata gaatgattac tagagcattt caatatataa
    22501 ttatagcttc atacattttt gttggtttaa tttcttgctt tggtatacta aatatgacca
    22561 ataccctaat aaacagcgtt ttaattagaa aaaaagagtt tgcattactt caagccgttg
    22621 gaatgacaag aaagcaactg cgaaatatgc tttatagaga aggtctaaac ataagtatca
    22681 aagctatatg tacttcaagt atactaggtt attttggttc aaatctactt tgcactttta
    22741 taaaagatgt aattagatta gactttatta attttaaatt ttctatattt actattttaa
    22801 ttttttcatt cgtattaatt ggtatacaag ttttagtgac tgaattactt gtaagaaata
    22861 tagaaaaaaa atcacttaca gaacgcttac gttctcagta agaatgtata taaaaaatag
    22921 ccatttttta tacaagtttt aacataattt tttaaaagct aaaaggatag aaaattttga
    22981 ctttacataa ttttctatcc ctatacttgt ttttatttta tacagataca cttccttata
    23041 tctccgagca acatcaccag agacataaac aagcatattc cttattttct aaatatgtca
    23101 attgcatgac ttgtaacccc tactaaatct tcacgttcac aagtagcaag gtgatatttt
    23161 aaatataatg caaatgcatc atcatccata gagtctactg cttcacgcat atataaagcc
    23221 aaaccatctg atgcgacata atgcagtcta gttacattaa atgcagacat caaatcatca
    23281 atgttttctt tacgtacaag ctcaaacaaa tcctttggtt cagacttagc agcaaatgtc
    23341 tgtggatcaa tcaaaccttt ttcaatatat tcagatacat taatatttcc tctatggaac
    23401 ccctcgtcaa tgagacagcc atcagatata acatatgcag caaaaaccac accaccaggt
    23461 tttgttacac gaattgcctc atgtaaagct tgttgtttat cttctttgtt ataaagatga
    23521 tatagtggtc ctaacagtaa cgtaatatca tatttattat ctgggaaaac agataaatcc
    23581 atagcattac cctgagtaat gcttatattt tcatttgatt gagtattttt atggaaaacc
    23641 tctatattat gttcgactaa ttccactgcg tcaacatcat atccctgacg tgccagtgtg
    23701 tgagaataac gaccagttgc agcgccaatt tcaagcacac aatcacctga ttttatgtac
    23761 ttatcaatgt aatgcatagt agtgagaaat tccaccattc catgttttaa tgcaagtcga
    23821 ctatcttcat cataagtatt ataaaagtca attaagtatt gttttgtttc cataatttca
    23881 cctcttctat attagttaat aaacatcaaa tagacaaatt ccaatctggt ttttcttgtc
    23941 ttataaaagc tgttaatata tttttcaaca ttttttcagc actatatcta tctaatgtta
    24001 atttttttgt tgctgttaag acagctatgc catgagtata aagaaataaa tctaaaaata
    24061 ttacttttgc acattccaac tctattccaa tgctttccga aaaaagtctt gccttttttt
    24121 cattgtcaat ttctttataa aaatcatttg cctcttccat catcaaatct aaatcattta
    24181 taaataacaa cttaaataaa tgagtttctt cttgagcaaa ttcaatgtat gaaagcggaa
    24241 gcagtaaata aggacttaca cttttagaat tactataatt aacaacatac tgattatagt
    24301 attcatatgc aaaagcaaga aattcatttt ttaattcatt catgttttcg taacaagtaa
    24361 aaattggtcg agtggaacac tgtaatttac ttgcaatact cctcgcattt acagcttcaa
    24421 atcccacttc tcttgtaata tccaagactg tattcaaaat catttctttt gttatcttta
    24481 ctttaggtgg catatatgtt cacctctcca ttaaattttt ataaaacaca tatgttatat
    24541 aactatagta acatatcaag aaattatgtc aagaaaaaac tttgcatttt tttgcaattc
    24601 ctaaaactta taaataaaac atgagttgca attaatctat taatagataa cagcaactca
    24661 gattttcctt taaatactct tctttttgtc taatatttca tatacacaat cttctattga
    24721 attaatatct ttttcttttc tttttttaga atcaattaaa atgaaataca gtataaaacc
    24781 tacagcaagt ccccatgttc cgcctttagc agcaattaca cctcccataa gtccaatcaa
    24841 tcccttctca acacctgtat tacatagctc cattgatagc tttgtacata aatatccttg
    24901 aactaaaagt gttactgaca atgctaatgg tataagaggt gtagcaatct gcgcaattgg
    24961 ataaaaacag ataaaaattg ctgaaaccca tactaatgta cccatgccac taaaaacaga
    25021 ctgcatggct tcctttccaa ccttgtacct ttgagcaaca cttcctgtaa gtgtcgcagc
    25081 taatggaccg cacattggta tatatggaga aaagattgcc ataaaaatat ttcttatccc
    25141 acttataaca ttagacctat ttgaattgaa atctatatat tcatcttttc tattttcact
    25201 ttcagaaagt actaagtttt cacctgttat aaaatcacca aaggcaatta tgtatatcat
    25261 aaaagccatt ggtatccctt gtataaataa cattacactt ggaaaaccta ttccaaaagg
    25321 agatactgta tttatcagat ttttaaaatc tactatgtaa actaaattgt caaaactaaa
    25381 tctaggaatt tctatttctt tactaaatat acctactatt aaactcacta aaatagctga
    25441 tactacacca tattctccta aatgaaataa aaacttattc ttaactttta gagtatcaaa
    25501 tctttcagaa aacattacaa aacaagcaac caaaattcct actgttatag atataggata
    25561 agaatcaaat ctccctttag gattaaactc tgatattata gtcgatatac cgacacccat
    25621 tagtattcca cctttaatag aatttggtat cttactaact aactttccag ctacaccagt
    25681 tatacccatt aaaataaata ttattcctaa atctatttgt aaagctgtta atgcttgtat
    25741 tctttcaatg cccatgctga actttaacaa atatgcagtt gtaagagtta tagaagctgt
    25801 aatccagcca ggtacaactg ggtctcccat aaaaacatgc aaacagtata atattgagtt
    25861 aatgatagcc atactccatg ccacttcata gggtaatccc aaaatttgtg tactaaggcc
    25921 aattgtgcct aaacttgtca tacttgatat tataccttga atagcttctg gtttctcaaa
    25981 tctgtaatgt ataaatggaa ttcttatctt aaacattcca aattttatat gagcttgttc
    26041 ccttctagcg agtctttcca taacttcact ccacctttca ataactctta taagtttaca
    26101 actttataat tgtttataaa ttatcaatgt cattaaaatt agtatataac atgcaaatta
    26161 tataaacaat aaattaaatc tataaaattg atagattttg tgcatatata gaaagaccgc
    26221 ttcattttta gttacttaaa tcacttaata ttagttattt aaatcacttg ataaaggttt
    26281 tttataaaat tcaatagttc tattccatga ttcaaactgt ccttttgaat ttccttctac
    26341 agttccacct gaagaaaaaa tccctccact catactcata cataaagtct cctttagagg
    26401 cataatatat ggaattggta acggatgacc catattattg tatgttaata attctacgtt
    26461 atatggataa ttattttctt caaagatttc taatgcctct aaacaagatt cataactatt
    26521 ccatatgtta tcttcttttc cagcaatcat aagtatatct gctttggaat tttctatttt
    26581 tattctagcc tcttttctat tctctgctct tttaagactt ttcttataag tactattaaa
    26641 tccaaatgga ataccttttg atatattttt tttctgttct tcaaaaaata tatcattgtc
    26701 tactttgata tatggaaatg gctctccttt atatgaccat gatgaagtat catttccact
    26761 catcaatcca ttaagagctt ggaaacaata aatgtgaggt tgtgatacta caaccttttt
    26821 aatttgttca tatcttgaag caagtaaaaa ggccaattct ccaccctttg atgtcccatg
    26881 tacaaatatt tctttagtac tggtaatttc attttcacta atccactcaa atactttttc
    26941 aaaatattct aatggaacct cttctaattt atctggtaac ccttctaaag caaagtatgc
    27001 aactgttagt acattgaatc ctctagatgc aagtggagct gctaaaaggt ctagagcgtc
    27061 taaattccca tcagaaccac ctagcattaa aattgtttta ttattagaat tttgtttata
    27121 aaataatttt cctataaact catcagatat gtattttgtg gtaatatctt ctgatttaaa
    27181 tattcttttt aattcaactt cttttctttc aatagaagtt tcaaatatca tattcataat
    27241 tattggttta tcaatagata tattttctgc aaaattttta ccttcagttt tagatttttc
    27301 cagcgaataa attaacccca tacaattatc agccttataa gtaccttcta taggttcaac
    27361 taaatctaaa tctacttctc ctttttcatt tgaacaaaac actccataag atgaaaattc
    27421 ttctcccttg caccatggaa attccatttt cacacttatt ttaagtttag tatttggaat
    27481 taagtctgaa accataatct taagtctttc atccacaaat gattctacat tgtatacatt
    27541 tactttcata atctatttct ccttataata attatttatg ttttatataa aacagcttta
    27601 tctaatgcaa cataaataaa tttttaaatt aagacaccat attgactatt tcattttatc
    27661 aacatattcc atttttgtca acatattgtc ttttttagta atttaaaatt atgtagtcta
    27721 tatgaaatcc agttgatttt tggctaatta aagataggaa tgctattagg tttaaaatat
    27781 atctattcaa aataaaaaac cactcatttt aagaatggtt tttaatataa actatttgtt
    27841 attaataagg atattttttt atttaaattt atataatcga acatctaata tttaatgttt
    27901 aataaaatta tgcatttgca aaagtatata tggcattaac tcttgctaca tataaattct
    27961 catcactaca tccaatatat ctagcatatt tttcaatctt ttcttttgca ttttcaacat
    28021 cattttcatc gctctccatt aactcattta tataaatatc cattaatgac gctttatatt
    28081 ctcttatatc atagcctaaa aattcagtca atctctcaat ttccttacta aaatctccat
    28141 cttcttttac caaaaattcg tatacatctt ccctatatgg atttaaagtt attatttgtt
    28201 ttactacttt gcattcgtca gccttcccaa taaaaccatc tttataatta ttaaataagg
    28261 cattagattt ttttatagat tcttcatcaa tataagaatg taccgcagtt atacgatttt
    28321 ctataagggc atctacaaca gcataatgaa ttttaaaaca atcattgtat aaataattgc
    28381 tcattttctt tattgtcgat tctatttcta agaagctagc gtgaccattt tttttatttt
    28441 tatttggtat aataaaagtt ttattcaaat tattaaaaag tctcttaaaa tctaaatatt
    28501 tttcacaata aacactttta aaggtatcga tatctatagt tataattcca aaacttacta
    28561 tagtctcaat tcctttctta aaagactctt ctatatattt ttctcctaaa cttaaacctc
    28621 tatcagatat ttgctttaga ttttgaaaac tatttaaaca atctctctca aagtttttag
    28681 atatttccaa agcatataat ttaaagattt tccttatctt attataatta ttttttgtat
    28741 catcaaatct gataatagct ccatttacat caaaagtaat cattgagttt taacctcccc
    28801 attagtttca tcaataaaat aaatttaata taaactttat aatcataata ttaaacttat
    28861 ttatactata attattaatt tgatgataaa agctattttc cttctaaata aaaaatttgt
    28921 ctaaagtttc taaaaaattt agacaaatct taggttatta ctctttaaat tatttttaaa
    28981 ttattccaaa tacgccaaat aatattggta taaatatagc tggtaacaaa ttggctactt
    29041 ttatattcgt taatttaagt acatttagac caagtcctat aattaataaa cttccagctg
    29101 ctgtcatttc tgtgactaca ggatcactta aaaatccatt taaaaatgat gctcccacac
    29161 atataatacc ttcatacaaa aatacagata ttgcagaaaa cattacacct atacctaaag
    29221 aagcagtaaa tataattgaa gctattccat ctataacaga ttttacaaat aaagtatcat
    29281 gacttcctgt aagaccactt tctaatgaac caactactgc catggctcct atacagaata
    29341 ataaactaga tgatataaag ccctctgcta tagaatcttt tttatttcct ttagaaaatt
    29401 tactttgtaa aaaagcaccc aacttattta cccatttgtc aatatctatt aattctccta
    29461 tcagagcacc tacagctacg gatattattg tcactaatgt gttttttcct tctagtgctc
    29521 ctgatatacc aatgtacaat acacataaag caattccatt cattatagta tcgcttactc
    29581 tttgaggtaa tcctcctttt attataagac ctactataca tccacctgca attgctagac
    29641 tatttgctat tactccaaac attttttctc ccctcgatta gctaattgaa atttatccta
    29701 ttattaaaac ctaaacatct atactttgta ttggatattt taaatattcc aaaaattctt
    29761 caaaaccttt tctagatata tttacagttt tagtatttat gttaggatga aaatttaagt
    29821 aatcttcttt aattacatct ttatctatgt aaagctcaac ttttctttct gtatcattta
    29881 ttaatgaaaa aggatttaca cttccaggaa gaagtttaag tacattgtat agtctttcag
    29941 gtgaagcaaa cgataatcta gaacttccta tcttatcttt aagtgagttt aaatcaactt
    30001 gtttttctcc tttaactaca ataagataat acttatttcc tttggcattt cttaaaaata
    30061 aatttttaca ttgacacccc tttgttattt catctaaaat gactaattgc tctgctgtat
    30121 atacagcttc atgctctact acatcatatt caacatttaa tttatccaaa atatcatata
    30181 ttttagtttc attcatgcta gattcatttt catcttgttc ttttttatta tttaaatcac
    30241 tcatactttt ctccttaaac acttcatcat aatatcattg tgaggtatta ttctactata
    30301 gctattgctc ttactggagc tccatcagca tcattatact taaatggtgc tgctataaat
    30361 agaaattttt ctggaacatt ttctaaattt gtaagatttt ctatgattat ttttcctttt
    30421 tcaaataaaa tatgatgcac ttcaaatact gatgtgtcat atctatccac tgatagcata
    30481 tctattccta tgccttttat attagtatta gctatatagt ttgcagcttc ttttgttaat
    30541 gtaggataac ctacatagta ctgcttttta tcccaaaatt ttgaccaacc tgatttaaat
    30601 attataaaat cactattttt tatttcatct tcatattttt ttagatattc taattctata
    30661 ttctcatttc ccttttcaag ttccaataca taagctttcc caacaaaatt ttctatatcc
    30721 aacttatcta gggtctcacc tttagtatac atatgtcttg gtgaatccat atgagttcca
    30781 ttgtgagaaa atacactaat taatgtttct tgataaccat tttcttcaat aatagctact
    30841 ttcttgatat ctggtctatt aggctctgca tatacaggca tgtcattatg tgtcacatga
    30901 gttaaatcaa aaaccttcat ttttatatac cccctatgtt tttattttct attatatacc
    30961 taaattcatt ttatttctat cagattttat tccattatat accatactac tatatatttt
    31021 ttataaacct caagggattt accgaaaaat cttggaaaga attatcagta aatataacat
    31081 cttcacccaa aaaacgttta taccttcctt cttctttctt taaagtaatt ctctgttttt
    31141 gtgaatggtt attaaaaacc attatcttaa gaggaggttt ttttctatta gtctgcactc
    31201 tttttaacat gtattttatg tgcatatcag cttcaggaaa tgaatatcca caaaatatta
    31261 aaaggtcagt atctcttaaa gttttttctg tttcattcca aacattactt aaaaatatgt
    31321 ttgacatatt cttaaaatat gttggtggca ctataatagg ttctgttaac tcaccacact
    31381 ctaaacattt tgtctctgaa ctattttcaa taagcttcat gacaccacct tcatgtggtg
    31441 taagagttac actattacaa atggggcaat aaagccaatt caatgaccca tgtatcttat
    31501 ataatttgat taatggttct tttggttttc tccaatttaa ctcctcttta aaatttgtaa
    31561 actccacacc ataatcaagc ataattggca aatcattctt atctcttaat ccagtaactg
    31621 tattgtctat atgtatatca taatttgcac taataaaagt agtatcaaga agcaaatcat
    31681 tttccaaaag attttcaact aaaagtttat gatatttatt atctgttcta ggtgtattat
    31741 gaattgcttc agccattagc agtattaaat attgtcttaa aaaacgtata ctatcacttc
    31801 tgttatttag attttctagt ccaaaatttc taaatgcttc ttttctttgt tctgctaagt
    31861 ctaaaagacc taaaacttct tcaaaggtag gaaaatttgc attatctata ttatctttta
    31921 ctatatcaat attgaacatc tgtttaaaga aaatatacaa ttctctattc attttggtat
    31981 tataatttgt gggatttagt tttttaaaat attcgctaaa aagttcattt tgaataggta
    32041 gattctctgc tgctgaagct cctgctccta aaaatattgc tattttcata tagttcctcc
    32101 taatataaat attactccta tttttatatc cattaaatat ccatatcatt tattttatga
    32161 tacaacaata aagctgtctt ttactagaaa aaatcctatt acaagacagc cttatattat
    32221 attaaatctt taataattcg taaatagaaa gagcatatat ttgagtagct tttataatat
    32281 cctctactat taagtattca ttagcttggt gttctgtttc tggttttcct ggaaaaatag
    32341 ctccaaatgc aacacaatta tctaaagctc ttgcgtatgt tgctcctcca gatgaaagtg
    32401 gtgttccatc aagaccagtt tcttcttcat atacttttct aagtgtctta acaagaagag
    32461 tatcttctgg aacatagatt gaatccaaga aatcatattc ttcataattt aaattgtatt
    32521 tatctgtcat tttctttaac tcttttacaa aatcatcctt tttgtatgtt actggaatcc
    32581 ttacatctat tcctgcaaat tctttttcgt tatcaatagt tactctacct atatttactg
    32641 ttagtttacc tgatacatca tccttgcaat taggaattat attgtttcca ttagcatctt
    32701 caccaataac ttctgctaaa aacttaatta tattagaatc tatacctata ttattaagag
    32761 ctatacaaag tctagccact gcatttatac cagtatcact tgctgctgaa tggacacttt
    32821 ttccaattat acagatttta ttaccctcaa cagtatactc aaaatttaat ttatcaagtt
    32881 ctttttttaa tttatcagag tattttccaa tatagattgc tttacctgga actgcattta
    32941 aagcctttcc aactgacaac tctatatcac ttttgctatc acaagtcaaa tgaacttgta
    33001 aaagaccttt ctctgcattt gttattggga atctagaatc tggagtaaat ccatagtttg
    33061 gtatttcttc attattttct ttatatttat ttatacatct ccaaagattt tcttcatcag
    33121 ccccaaaaat gaatcttatc ctcttattaa agtctacatt taaatccata agagctttca
    33181 ctgcataaat tgctgatatt gtaggtcctt tatcatcttg tgttcctctt ccatacaatt
    33241 taccatcttc taaaacagct tcaaatggag ggtaattcca gctttctaaa tcaccttctg
    33301 gaaccacatc aacgtgacca agtataccta tcattttttc accttgtcct atttctgcat
    33361 atccataata tccatctttg tatactgtct taaatcctaa agatttacat aagtctaata
    33421 tacctcttaa agctttatct acattttcac caaatggaca attttcagtt gcttcagata
    33481 taacactagg tatttttaca ctttcttgta ttgaagaaat catttcatct tgtagagaat
    33541 ttactttttc tttaatttgc tctttcatat tatcaccctt caattttcat cataatatac
    33601 taataaatat tttgaccttt taaaaaaaaa atatgcttat tttttcagtt tttttataaa
    33661 ttcaatcgct tttaaagtcc ccatttttga atggtcaaat gtaagtccac cttgaaaata
    33721 aacattataa ggaggtctta ttggagcatc tgcacttaat tctatagaag aaccttgtat
    33781 aaatgctcct gctgccatta tgacttcact ttcgtatcca ggcatgtccc aaggaacagg
    33841 ttttacataa gaatcgactg gtgcagcttc ttgtatacct tcacaaaaac ttattacttc
    33901 atcagcatta ttaagtctaa tacattgaat aatatcactt cttaagtcat catattttgg
    33961 taatacatca tatcctaatt tttcaaaagc tcttgagcaa aagatagctc ccattacagc
    34021 ctgagatact atataaggcg ccaagaaaaa accctgaagt acatttctag ttgttccaaa
    34081 agtaagacca cattcttttc ctattccagg agaagtcatt ctataagata taagctcaat
    34141 caaatctttt ctaccagcta tatatccacc tgtcaatgca agcccaccac caggattttt
    34201 tattaaagag ccagccataa catctgctcc aacatcagta ggctctttgg tatctaaaaa
    34261 ctcaccataa caattatcaa ccattactat agcttctggt ttaacagact ttattacttc
    34321 tatagcttct tttatatcac taattgaaag tgattttctc caagaatatc cttttgacct
    34381 ttgtatcata acgagtttag ttctatcatt tattttgttt ttaattcctt ctaaatctaa
    34441 gtttccatcc tctaaaaaat ctacatcatc atatgtaaca ccatactctt tcaatgaacc
    34501 tttttcttct cttatgccta taactccctc taaagtatca tatggtctac cagtaacaga
    34561 taaaatttca tctcctggtc taactatacc ttgtatacat aaagtaagtg catgtgtacc
    34621 atttacaatt attggtctta caagagcatc ttctgtatta aatactttag aataaatttc
    34681 ctctattttt tcacgaccaa tatcattata tccatatcct gtagtccagt taaagtgcat
    34741 atcacttagt ttagattctt gcatagcttt taaaacttta tattgattat attctcttat
    34801 ttcttttatt tcttcaaact tatcttttat ttcttccatt atttcttgcg atagtttaaa
    34861 agtatcatca tctattccat agtagtcttt taataattct tttgtctcat taagcatttt
    34921 atcacctgtc tctttattat tttatttaaa catgtaaagg agactatttt actaaaacaa
    34981 ataaattata gtttataagt tagtataagt ctcctctcaa tcatcttaaa ttaaattaat
    35041 tatctatctg ttgttattat tattgttgtt ttggttttga tttgttagat taatatactt
    35101 tccaggttgt atagttgata cagcatgttt ataaatcatg ttttgttgtc tattatcccc
    35161 ttctattaat attatataac tatcaaaccc ctttacaagc cctttaactt gcactccatt
    35221 aactaaatat atagtaacag gtatcctttc tttccttgca ttatttaaaa acaaatcttg
    35281 taaatttaaa actgtatttt tcattagatt tgtaccctcc caagattaaa ttgaacttct
    35341 aaaatattcc taccttatat tctatataag ttatgacaaa ttttcaatat taagttgtat
    35401 acttaaaaat ttatatatta ttttatagaa tctttaatat ataagattat ttcatttttt
    35461 aattcgtcta tattttcata ttggtctaaa tcaaaccatt ttgctgtttt atatctttta
    35521 aaccatgtta tctgacgttt tgcatacctt ctagaatctc ttttaattat ttcaatagct
    35581 tcttcgtatg tatattctcc atccagatac tttaatatct ctttataacc tataccttgc
    35641 attgatatca tatctttttt aaatcccata cttaaaagtt tttttacctc ttcaaccaat
    35701 ccatttttaa tcataatatc aactctcata tttattcttt gatacaaatg ttctctatct
    35761 ctatttagaa ctattattat tggttgatat tcttcattaa attttaaatc acttgaaaaa
    35821 tcattcattt tcttaccact tagacaaact tcaagagctc ttatgaccct tttagtattg
    35881 tttttatgga ttctattagc agattcttca tcaagttctt ttaacttatt atgcatgtaa
    35941 tctattccct tttcagcaag ttgtttttga agttcttctc ttaattcatt attggcatca
    36001 gattgtgcaa aatccatatt atatattaaa gagtttaaat aaagtcctgt gcctccagtt
    36061 actaaaacac atttttcctt tttatttatt tcatgtatat atttttttgc tctttgttga
    36121 aactctgaaa ctgaaaatgg atagtcaggc ttaacttcat ctataaggta atgcttcact
    36181 ccttgcatct ctttctctgt aacttttgca cttccaatat ccatatattc atatatttgc
    36241 atagaatcag ctgaaattat ctctgcattc atatcttttg ctaattttat tgacaaatct
    36301 gtttttccaa cagcagttgg acctgtaagt attataagtg gtattttttt cataacattc
    36361 ctttccatat attttaaata tccaaatatt ttacataatt cttttaaaca ttttttctat
    36421 ttctgtctta gatatttcga ccattatagg tcttccatga ggacatgtaa atggattctc
    36481 acacttttct agctgttcca ataaactttt tatttcaata tcgtatattt tatcatttgc
    36541 ttttatagca gacctacatg ccatagatgc aaatctctct ccttttaaat cataattact
    36601 tgtaatttct tctatattat caattatttg aagtataaat ttctcagttt caggtactcc
    36661 aaatatagta ggaacacatc ttaccattat atgattattg ccaaaaattt ctagctcaaa
    36721 accaaatttc ataaataact ccaagttatt ttcaatttga agcatatcta catttgatac
    36781 ttcaataacc actgggtcta aaagtatttg catatttata tcttgtctat agaacttctc
    36841 catatatctt tcatatagta ttctttcatg tgcagcatgt tggtccaaca aatacataga
    36901 atcatctttg ctcaaaatta tataagtatt aaatacaact ccaattacag aatatccgta
    36961 taaagaaaac ttgcgttttg aactacacaa gtattcttct tcactgtcct taatactatc
    37021 tcctaagtaa taatttcctt catttttaat tccatcaact tgaaactctt cttgtatatt
    37081 atcatttgca ctatcttcac ttagataatt aatgtttttt acatcatctt ctacacttgc
    37141 atttaggact tcacttactg attgaaattc atttattggt ttttcacttg ataaagtaac
    37201 aacttcaatg acttcatcct tacctttagt aatattacta tttttaggag tagattctaa
    37261 taaatcatta tttcttaatt tataatctgt acttttttct ctactgttaa tagcgattct
    37321 aggttgtgtt tttttatcac tataagtagc atattttcca ataagatttg agtgtattaa
    37381 tttaaccttt aaaaaatctc taagttctat atacacttct tgttcttttt caaatttaat
    37441 ttcaagttta ttggggtgta tatttacatc tatacatgat gggtctactt ctatatttaa
    37501 gaagcacact gcatgtttac ctattggaat tatagactta taactttctg ttattgcatc
    37561 tatgattatt ttacttttta caaatctttt atttatatag atatgttgta agtttttatt
    37621 tgaacggtat atattgttat tacctatata tccattcatt ttaaaatgat tgcacttaaa
    37681 ctctacatct attatatttt ccgttatttc ttttccatat atacttctaa tagtgtttac
    37741 aagttttcca tcccctggag tatttagcat ctgtttattg ttatttgtat atttaaattg
    37801 aatgtttgga ttacctattg caagtttatt tatcaaatca cttatattta tagtttctgc
    37861 atgagtagat tttaaaaatt tctgtcttgc tggtgtatta aagaaaatat cttttataat
    37921 gatggtagtt ccattagtag aacctattgg ttctttcgat attatttttc caccttcaac
    37981 atatatttta gttcctatta tttcatcttt agttttagtc gtcatttcta attttgatac
    38041 agctgaaata gatgccaatg cttctcctct aaaaccaaga gagtataaat catacaaatc
    38101 atcaattttt ttaattttac tagtagcatg tctcaaaaat gatttttcaa cttcacttga
    38161 aggtattcct attccattat ctgtaatctt aattagactt tttcctccat caattatatc
    38221 tatggaaatt ttatttgcac ctgcatcaat ggagttttca ataagttctt ttactacaga
    38281 agaaggtctt tctacaactt cacctgctgc tatcttattt atagtcaaat catctaggat
    38341 gttaattata tttttcattt ttacacctct aagattttat ttcttttgct tttctttgaa
    38401 gattataaag agagtttata gcatctaatg gagtcatatt taaaatatcc agatttaaaa
    38461 tttcttctga tagtatatct ctatttacac tatcaaaaga gatttgagtt aaggctactt
    38521 cttttacaga atcttcttga ttaattttct ctttatcatc attttgcttc attaaagcaa
    38581 cttcatcatt taatgcttta aatttagaat ttaatttatc ataatccttt tttatatgtt
    38641 tgtagtcttt tactataagt tcatgttcta tttttagaga ttcatattta ttcttaaaat
    38701 tactttgatt taccttaact aattcttcgt ccaaattact attaattata ttattgtttt
    38761 ctttatctcc atttattgca acactgttgt aaacatgatt tttttccaag tctttaagta
    38821 tatattttgc tctttctatg acttcgtctg gtaatttagc taatttagca acatatattc
    38881 cataactctt gtctgctcct tgaggaatta tttttcttaa aaatattatt ccttccccat
    38941 cttctttgac tgctattgaa taatttttaa cctctttaaa ctcttcttct aaatcagtaa
    39001 gttcatgata atgtgttgca aataatgtct tacatctaat atttttttga atatattcca
    39061 ctattgacca tgctaaactt ataccatcat aggtactagt tccacgacct atttcatcta
    39121 atataactaa acttctctct gttgcatttt ttaatataag ggatacttcg ttcatctcta
    39181 ccataaaagt agattgacct tgagataaat cgtcactagc tccaactctt gtaaatattc
    39241 tatctaatat tggaatatca gcagactctg ctggtacaaa tgagcctata tgtgccataa
    39301 gagctattat agcagtttgt ctcatatatg ttgatttacc tgacatatta ggaccagtta
    39361 ttatgttaat aatgttttct ccacgattta aataagtatc atttggaacg aaattttcct
    39421 ctcctactat attttcgaca acaggatgtc taccatttct tatatcaagt ttattatttt
    39481 catttattgc tggttttaca tagttattta tatgtgcaac tgttgcaagg gacacaaaaa
    39541 catctatatt agctatagtc ttagccactt tttgtattct atctatgttt ttatatattg
    39601 tatctcttat ctctacaaat atctcgtatt ctaaagattt aatcttttcc tctgcatgta
    39661 gtatcttttc ttctatttcc tttaattctg gagttatata tctttctgca ttactaagtg
    39721 tttgctttct tatatatgtc tcatctagct ttgcttgttt aaagttggct tttgttattt
    39781 ctatataata cccaaaaact ttattaaatc ctatttttaa tgatttaact cctgtttttt
    39841 ctctttccct gttttctatt tcctttacaa gaaaggctcc attcttagaa atctctctta
    39901 gttccttaag ttcatcacta aaatctgatt taattatgtt tccatctttt atggttatcg
    39961 taggttcttc tagaatagct tcatctatta aattgtatat atcatctaat ttatccattt
    40021 ctgaaacata ctcttttagg atttttgcat ttgataaatt tatagtatct tttaaattag
    40081 gtaacttttc tatcgaattt tttaagtgaa ttaactcttt tggtgttact ctctcaaatg
    40141 ctatctttcc acatattctt tctatatcgt atatattttt aagtatatca tttaggtctt
    40201 ctcttaatat aaagtcatct tttatttctt ctattacatc taatctattt tcaattttag
    40261 atttatttat caaaggttct tctacatatt ttcttaaaag tctacctccc attgctgtag
    40321 aagttttatc aagtacgtgt aataatgaac cttttttctt atttcctctt atagtttgag
    40381 taagttctaa attagttcta gtaaacatat ctagaaccat atattctgat gaattgtata
    40441 tatttatatt attaatgtta gatgttattt gtttttgagt attgtatata taattcagaa
    40501 gaattgataa gcttgacttt attagacctt tatcatcaaa ctttagtttt tgtagataaa
    40561 catctggaaa atattctttt aatatattta tatccaaata gttatcacta aaactttcat
    40621 ttatgtatat attacttaca gtagctatat ctctaagctt ttctataaag tctaaatcat
    40681 ttataattat ttcagttgga tggatttttg caatttcttc aattacctta tcttcattta
    40741 aacatgttgc attagtttct cctgtactta tatcaacata agttagacct atattagtac
    40801 catccttata caaagataat aaataattat tctttttatt ttcaagtaaa tttccatcta
    40861 aaactgtacc aggagtgatg acccttataa cctctcttct aacaattcct tttgctgtag
    40921 atgggtcttc catttgttca cctattgcta ctttatatcc attttcaact aattttgata
    40981 tatatgaatt ggctgagtgg aaaggaacac cacacatagg agcacgttct tctaaaccac
    41041 aagcttttcc tgtcaatgct atttcaagag cttttgaagc tactaatgca tcttcaaaaa
    41101 acatttcata aaaatctcca agtctaaaaa acagtataca gtctttatat ctatttttta
    41161 cttcaagata ctgtttcatc ataggagtta atttattcat atctatttgc attatcaaac
    41221 ctccttcttt tctaattaaa tattatatca tagtagatga ttattattaa cacaatatat
    41281 aaaattttga catataacta aaaacaatcc aaaatgtata ctcacatttt ggattgctaa
    41341 gtttaatgct tattaaataa aaatattttt ttttacaata aagatattat ttctttttta
    41401 agtttaatga tattttcaag gttatcttca tttaactttc tactatctat aacaaattct
    41461 ttctttacta ttgatggttt ttttgaaata acataaattc tgtttgatag cattatagct
    41521 tcgtcaatat catgagttat aagaagtatt gttgaattta cttttttctt aacatctaaa
    41581 agccattttt gcatggatgt tttagttaat gaatcaagtg ccccaaaagg ctcatctaaa
    41641 agcattatgt cattagaatt tataaaagtt ctcaagaagt tagccctctg tctcattcct
    41701 ccagaaagtt ctgaaggata tttatcttca tatccgctta atccaaacac ctcaaaataa
    41761 ggttttacca ttgacctagc tttactcttt ttttcttttt ttaaaattag tggtagtgac
    41821 acattatcta ttatagtttt atatggcaag agtaaatctt tttgatacat ataactatac
    41881 ttaccattta tattcacttt gccactatca taatctgtaa gtttagttat aatattaaaa
    41941 atagtacttt ttccacatcc acttggccct aatatagaaa caaactcacc ttcataaaca
    42001 tcaatactta tatcttttaa aacttcaata tctttataag tttttgatac attttctata
    42061 gatactttta cttttttatt gtggtaaaaa ttcatttgtg taagcatcac ttgccttcat
    42121 atccttatct attaatttat attcttttaa gaatgatgta tagttgttcc atacactatc
    42181 tttcatttct ccccatcgtg gtgcatcatc tttgtacttg cttgctaaat attcttgact
    42241 ctttaaagct agtttttcat ctacttcagg tgcatgtttt actaaaattt ttgctgattc
    42301 ttctggattt tttattgcat attcataacc ttttgttgta gcttttaaga attttttagc
    42361 aagctctgga ttatctttaa gcacagtttc attagaaatt ataagtggtg tataataatc
    42421 caatctctca tctaaatctt ttactgggat aaagtttaag tcatatccaa ttaaatcagc
    42481 tttaactgca tcccaacctt caaatatcca tgcaaaatct acagttttca tagctgcaaa
    42541 gaaatcatct tgaccagtat taactatctt taacttatta aaatcagctc catttttctt
    42601 cataactgct ttaaaaacag cttcttctga tggagagccc caaccaccat aagtttttcc
    42661 ttcaaaatct ttagctgttg ttatattctt ttcttttggt gatgcaaacc cagaagtatt
    42721 atgttgtata acagttgcta cagcttttat tggaagtgga tcttcactag tctttgcata
    42781 agtaacttgt tcttgatagc ttataccaaa gtcagctttt cctgttgcta ctaaagtttc
    42841 tgctccactt tcaggtggtt gtactatttc aacatccaaa ccttcttctt tatagtaacc
    42901 cttatcaagt gctacaaata atccagtatg atttgtattt ggtgtccaat caagcaccat
    42961 agttactttt ttagaagaag tatctttatc attgtttttg tctttattgt tatttgaaga
    43021 acatccagtt attgttgcca atgtaaaaac acttactaaa cctaatattc ctaacttttt
    43081 aaaattcata attgcctccc tcaaatacct ttaatctatt aatctatgtc ttataacaac
    43141 tttttttaca gcctgtacaa ttcctacaaa cattaaacta aatataacta ctaatatagt
    43201 agatgcaaat actttatcaa gtgcatatgc actttttgac ctaagcatat aaacaccaag
    43261 tcctttcgtt ccacctagcc attctgcaac agttgctgcc attacagcat acgttgcaga
    43321 tattttaagt ccagaaaaaa atttatccat tgccatagga aatttaaggt gaatgaatgt
    43381 attaacttta tttgagtcca tagtcttaaa taaatttaaa taatctttat caatattctc
    43441 aatgccatct acaaaactta ttaatatagg aaaaaaacaa gtaagcatta ccatcaatac
    43501 ttttggcatt gttccaaatc caaaccatat cataaagagt ggtgctataa ttattgtagg
    43561 tatcatctgt gtaaccaaca taataggata aagacatttt tttattattg atacaaaatc
    43621 catcaatatt ccaattacca atgatattat aattgcgact ataaaaccaa gtattgcttc
    43681 tcctatagta accacagcat gcatggataa attttgataa tctttaaaaa acacattaat
    43741 tatatctact ggtgtgggta gtatatactg aggaacttct aaaactccta ccatagattg
    43801 ccaaagaata agtataaaca aaaatgttgc tattggatat atactatctt tgactttatc
    43861 tatgatttct aagtttttca tctatagtca gacctccagc tttttcatct actctagcta
    43921 ctgttatgac tctttcacat ccaagattaa aagggatttt atgtaccttt tttaataatt
    43981 caaaaacttc atcaaaatca ccttcaacag tagtgctcat tgctcctatt tcacatttaa
    44041 gaccactttt ttcaatttca gcaatacaag catctactac tttatacatc tcttcttcac
    44101 ctttgtaagg tcttagtggc attactgcta tgtctgcgat taccatttaa atcactcctt
    44161 taaaaataat taatacctac taggtatatt ttgtttttta ttaaaaaatt ttattactaa
    44221 aaagatatta tatttaaata aaagaaaagt cttatccaaa ataggataag acttattttt
    44281 atcttaactg gtctccctac actggcatta tccaaacagg ttcaaagggt cgagataaaa
    44341 tctcctctca gcacattagc tccccgaaat atattatatc ttttctactt gattatacta
    44401 cacttatcat attttaacaa attttttatt tatattagat attttatccg ttcaaaaata
    44461 tctaatataa attgtacatt attacaccaa ataaattatc ttaaaatggt aatttatcaa
    44521 catcttccaa aactagatta actgaatttt ctagttttta ttttgctatt tcaagcatat
    44581 ttggatgtat atcaattcca tacaaatatt gttctaaatt tctgttttca ctcatctaat
    44641 ttgcaatcgt tacagattac agattagaaa cagtttttag actctactta tctttatcta
    44701 caaaaaatct ttcaataaat tcagtaataa tattcagtaa tctaaaaata aacctctatc
    44761 tagattttta agatacaagc cttttaataa gtatcttttg tgataatata aaaattactc
    44821 gtcattatca tcaaaatcct cagcaaccaa cattttatat aagaatcaaa ctctataata
    44881 taattatttt atccaattta tttttgagaa ataaaatatt tttttaattt ttaaattttt
    44941 taatatgcac cttgaaaaaa gaaacgtttt cctatattat ggtaatagta gaataaaact
    45001 aaataggcaa aactagagaa atttagtgac gcaaagctat agggactaag acttatgaaa
    45061 tgagttatgt cagccagttg ccaaagagat attttctttt tgtttttatg aatgtttttt
    45121 agggggatat atgatatatg tttatggata aaatggatag atgtacacat atactaactg
    45181 catatatatg cagttcacgc gattactgca attttataga tacacaatta aatgatttta
    45241 tactagaata tggagagaat gtggtagaat cttgtttgca tcaagtgatg gtattggtaa
    45301 gcagatataa ttaaagaaat tttattttct agaaaaccct ttttagtttt atctacgttt
    45361 tataattcat taaagaacta attaaaataa gcttcattat atatttttca taaagtaaac
    45421 agttgagttt atctcatata ctgtttaccc caattacata attctaataa tatagattcc
    45481 aatgatttac cacgtttagt agacaaatat tcaacttttg gaggaatagc cggataagaa
    45541 atcctcttaa taagtccatc tctttcaaga tactttaatt cttgtgacag tatcttatga
    45601 cttatatgaa caacttcttt ttttaattga ctgtaacgta ttggctcttg ttttaaaata
    45661 tgccataaaa taattgccct ccatttactt cctatcacag tcatggtaaa accaattgaa
    45721 caattaaaat ctttttgtct ttcttcaata tttgaaaatt cttcaaaatt attatctata
    45781 tccatctcaa tcctttcttt caaaatagta agtatctaac taaaaagtgc attcttgttt
    45841 agcgtactaa ttcgtaatat aatcttgatt gtagtataga gccttacata atactacttt
    45901 tttagatgta tatgtttaaa ttttaatata gacatatgtt attttattaa ttttatttaa
    45961 acagataata ataaataata atttatctca agttttctat gtagataaac taatctaatg
    46021 tttagaaagg attatataat atgaataaaa aatttcgtct ttatcaagtt gactcattac
    46081 aaaagaaaaa tttataggta atccagctgg tgtaattaca aatgctgatg gcttatctga
    46141 atcacaaatg caaaaaatag caagagaatt aaataattca gaaactgctt ttattttcaa
    46201 taacttggct aaaaatcatc aagaaaatta tgatttacat atcagatttt ttacaccaac
    46261 taatgaggtt cctatatgtg gtcatgctac tattgctgcc cattatgtta gagcagtaga
    46321 aaaccaattc aataacaaaa cagtatttca aaaaactggt gctggaatat taccagttga
    46381 tgttataaaa aaagataatg attatgaaat aattatgaca caaggaaaaa ttgaagtatc
    46441 tccaccatta caacaaacct atcaaaaaag attacttaat gcatttggta ttttaaagga
    46501 agatattcgt acagattgtc ctattgccat atcatctaca ggacattcaa aagttatgat
    46561 tggaataaag gaattatcaa cattaaatag tttatctcca aatttatatg aattatcgaa
    46621 aataagtcaa gaaataaaat gtaatggata ttatattttt acattacata ataaagaaac
    46681 tctacaagtt catggaagaa tgtttgctcc tgcaattggt atttcagaag accctgttac
    46741 aggaaatgct aatggaccct taggtgtgta ccttgtacat tataaagtaa tacctacacc
    46801 caacacagag tttatatttg aagcagttca aggagaagca ataaaacgca aaggcaagat
    46861 gttagtaaaa gtaattattt tagataataa gcagttgaag taaaaataat tggaaaagct
    46921 gtaattgcat tctcaacaaa catagaaatc taattataga ttccttctaa gtaaattttt
    46981 gaacttttta atactaattt aataacaaac taatttatat acaatcaaat taattttttt
    47041 attatttgtt aatat
//
LOCUS       DAEPXW010000021        46891 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.021, whole genome shotgun sequence.
ACCESSION   DAEPXW010000021 DAEPXW010000000
VERSION     DAEPXW010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46891
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.021"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            44..622
                     /locus_tag="KRM55_001154"
     CDS             44..622
                     /locus_tag="KRM55_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH1593405.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            738..1649
                     /locus_tag="KRM55_001155"
     CDS             738..1649
                     /locus_tag="KRM55_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH1593406.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            2256..4175
                     /gene="cooS"
                     /locus_tag="KRM55_001156"
     CDS             2256..4175
                     /gene="cooS"
                     /locus_tag="KRM55_001156"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH1593407.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKSGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            4485..5264
                     /locus_tag="KRM55_001157"
     CDS             4485..5264
                     /locus_tag="KRM55_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1593408.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            5513..7189
                     /locus_tag="KRM55_001158"
     CDS             5513..7189
                     /locus_tag="KRM55_001158"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBH1593409.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            7294..7926
                     /locus_tag="KRM55_001159"
     CDS             7294..7926
                     /locus_tag="KRM55_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBH1593410.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            8018..8890
                     /locus_tag="KRM55_001160"
     CDS             8018..8890
                     /locus_tag="KRM55_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBH1593411.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            8927..9601
                     /locus_tag="KRM55_001161"
     CDS             8927..9601
                     /locus_tag="KRM55_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBH1593412.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            9637..10518
                     /locus_tag="KRM55_001162"
     CDS             9637..10518
                     /locus_tag="KRM55_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBH1593413.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            10562..11947
                     /gene="lpdA"
                     /locus_tag="KRM55_001163"
     CDS             10562..11947
                     /gene="lpdA"
                     /locus_tag="KRM55_001163"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH1593414.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            12003..12773
                     /locus_tag="KRM55_001164"
     CDS             12003..12773
                     /locus_tag="KRM55_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1593415.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            12793..13737
                     /locus_tag="KRM55_001165"
     CDS             12793..13737
                     /locus_tag="KRM55_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBH1593416.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            13768..15135
                     /locus_tag="KRM55_001166"
     CDS             13768..15135
                     /locus_tag="KRM55_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBH1593417.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            15185..15991
                     /locus_tag="KRM55_001167"
     CDS             15185..15991
                     /locus_tag="KRM55_001167"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH1593418.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            16048..18174
                     /gene="cdhC"
                     /locus_tag="KRM55_001168"
     CDS             16048..18174
                     /gene="cdhC"
                     /locus_tag="KRM55_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBH1593419.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            18261..18638
                     /gene="gcvH"
                     /locus_tag="KRM55_001169"
     CDS             18261..18638
                     /gene="gcvH"
                     /locus_tag="KRM55_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBH1593420.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            18750..20678
                     /locus_tag="KRM55_001170"
     CDS             18750..20678
                     /locus_tag="KRM55_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBH1593421.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            20703..21575
                     /locus_tag="KRM55_001171"
     CDS             20703..21575
                     /locus_tag="KRM55_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1593422.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            21572..22510
                     /locus_tag="KRM55_001172"
     CDS             21572..22510
                     /locus_tag="KRM55_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1593423.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSAGVNKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIS
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            22557..23372
                     /locus_tag="KRM55_001173"
     CDS             22557..23372
                     /locus_tag="KRM55_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBH1593424.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            23523..23714
                     /locus_tag="KRM55_001174"
     CDS             23523..23714
                     /locus_tag="KRM55_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBH1593425.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            23733..24149
                     /locus_tag="KRM55_001175"
     CDS             23733..24149
                     /locus_tag="KRM55_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBH1593426.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            24165..24515
                     /locus_tag="KRM55_001176"
     CDS             24165..24515
                     /locus_tag="KRM55_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBH1593427.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            25061..25840
                     /gene="hisJ"
                     /locus_tag="KRM55_001177"
     CDS             25061..25840
                     /gene="hisJ"
                     /locus_tag="KRM55_001177"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBH1593428.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGEELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNKILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLDLVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(26153..27034)
                     /locus_tag="KRM55_001178"
     CDS             complement(26153..27034)
                     /locus_tag="KRM55_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBH1593429.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKISEG
                     EIELPDPIIMENDKLMK"
     gene            27587..28099
                     /locus_tag="KRM55_001179"
     CDS             27587..28099
                     /locus_tag="KRM55_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593430.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KMDFQEEYGKEDKFNITLNDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            complement(28924..30021)
                     /locus_tag="KRM55_001180"
     CDS             complement(28924..30021)
                     /locus_tag="KRM55_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH1593431.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            30314..31840
                     /gene="glpK"
                     /locus_tag="KRM55_001181"
     CDS             30314..31840
                     /gene="glpK"
                     /locus_tag="KRM55_001181"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH1593432.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            31881..32996
                     /locus_tag="KRM55_001182"
     CDS             31881..32996
                     /locus_tag="KRM55_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH1593433.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(33277..34041)
                     /locus_tag="KRM55_001183"
     CDS             complement(33277..34041)
                     /locus_tag="KRM55_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH1593434.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            34300..34390
                     /locus_tag="KRM55_001184"
     tRNA            34300..34390
                     /locus_tag="KRM55_001184"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34334..34336,aa:Ser,seq:gct)
     gene            34478..35266
                     /locus_tag="KRM55_001185"
     CDS             34478..35266
                     /locus_tag="KRM55_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBH1593435.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEISE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            35287..36027
                     /locus_tag="KRM55_001186"
     CDS             35287..36027
                     /locus_tag="KRM55_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH1593436.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVESGSNDLDTLQNAKFKKVGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            36203..36577
                     /locus_tag="KRM55_001187"
     CDS             36203..36577
                     /locus_tag="KRM55_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593437.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKVNKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            36669..38129
                     /locus_tag="KRM55_001188"
     CDS             36669..38129
                     /locus_tag="KRM55_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBH1593438.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            38182..41211
                     /locus_tag="KRM55_001189"
     CDS             38182..41211
                     /locus_tag="KRM55_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1593439.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIGMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            41288..43354
                     /locus_tag="KRM55_001190"
     CDS             41288..43354
                     /locus_tag="KRM55_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH1593440.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    43779..43989
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            44215..45030
                     /locus_tag="KRM55_001191"
     CDS             44215..45030
                     /locus_tag="KRM55_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1593441.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            45058..45735
                     /locus_tag="KRM55_001192"
     CDS             45058..45735
                     /locus_tag="KRM55_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH1593442.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            45794..46516
                     /locus_tag="KRM55_001193"
     CDS             45794..46516
                     /locus_tag="KRM55_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH1593443.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT        18335 a         5137 c         8954 g        14465 t
ORIGIN      
        1 aatgtacaaa taaattaaag cacatattga aaggatgtat aaaatgaata tcaatgaatt
       61 tttaacacat atcaatcaaa gaaaacctgt ttctagtaaa tcagaaatac atgaatttat
      121 ggttaagttg agtaatgaag caatgaaaat cacaagtaag ttaaattctt cttatcatga
      181 accagaagaa gtccgtagtt tattttctga gttaattgga aaaaaggtag atgaatcatt
      241 ttttatgttt ccaccatttt atacagattg tggaaaaaac atcacaatag gaaaaaatgt
      301 ttttataaat agcagttgcc attttcaaga ccaggggggg attgagattg gagataatac
      361 gcaaattggg cataatgtgg tattggctac acttaaccat ggtattgcac cagagaaacg
      421 tggtacaact tatccttctc caatcacaat aggaaaaaat gtatggattg gtgctaatgt
      481 aactgtagtt ccaggagtta ctattggaga taatgcaatt atcgctgctg gagcagttgt
      541 aacaaaaaat gttgcagaaa atactattgt aggtggtgtt cctgcaaagc ttttaagagt
      601 tattgatgaa atcccagaat aaaatattaa actgtctttt agttatataa attctttata
      661 acataaaaaa taaattgaga aaaggtatag caaatatggt attatttagt taaatatata
      721 taagggaggg gttacttttg ataaaaaaat tagatgatat tttagaacaa cttaagggag
      781 gagagaaaat tgtactctct gtagcagcag ctcatgataa agaagtttta atggcaataa
      841 aggatgctgt agaaagaaat ataattactc ctatattggt tggaaatgaa ggcaaaataa
      901 gagaaatatc aaaagaaata ggatttgatt taagtggtat caaaatagtg gataaggatg
      961 atatcaaaga gtgtgcagaa atagcagtta aattagtatc aagtaaagaa gccgactttg
     1021 taatgaaagg attattagat acatctgtca tattaaaaga agtgttaaat aaagactatg
     1081 gtcttagaac tgatagttta ttaagtcatg ttatggtata tgagttagaa aaataccata
     1141 aattacttat aactacagat ggaggtatga atatagctcc tgattatgaa caaaaggcaa
     1201 agatattaaa aaattctata aaagctgcaa aagctttagg aatggaaact gtaaaagttg
     1261 catgtttggc agctaaagag aaagtaaatc ctaagatgca agcaactgta gatgcagata
     1321 tgttagcaaa agcttgtaaa gaaggagaat ttggtgaaaa tgtaattgta gaaggtcctc
     1381 tggcttttga tttagctgtt tcaaaagaag ctagtgagat aaaagggttt aaaagtgaag
     1441 tatctggaga tgtagatatc atattggttc caacaataga ggttggtaat ggaataggga
     1501 aagcctttac atatatggca gactctaaat cagcaggtat aattatgggt gcaaaagctc
     1561 ctatagtttt agtgtcaaga gctgattcac atgaatctaa attatattct attgcatatg
     1621 gggctattgt agctaaaaat atgaaatagg ataaatcgct tgaaataaat gaattaaagt
     1681 agaaaaaata gtcaaaatgt ctaaattaat gctgtattaa aaaagtttta tataaaaaat
     1741 aattatagct tcaaatgaat atatacaaat gttcaatttg aagctataat taatattaaa
     1801 gtaggaaaaa taaaaaaatt caaaaaaatt agtccaaaaa atgctattct aagaagtttt
     1861 tactaattaa gtttagggag taaaaatctg taataagtcc aaacagtagt gaaagataat
     1921 aaatacacaa acaatctgca ataatataaa aatgactaga aaaatttcaa atttgattta
     1981 aaaaaatcaa aacataattt aattaaactg aagtatcaaa aaagtaggtt tagatattaa
     2041 caaatagcca aaaacaagcg ataaaatcaa cttaaattaa gtgtagaaaa taaaattttt
     2101 atgtattatc taattttgtt aaaaaaatat ttaaatctaa agcaaagcac tgaaaattag
     2161 tatataatca acttagaaag catttatttt attattttat gacatgaagt cagtcacctg
     2221 ggggatttta aaaatcaaaa aaaggggata ggaatatgga tgaaaaaatg ttaacaattg
     2281 atttaaacag ccagaagatg atagctaaag ctagagaaga aggcgtagaa acaatgtatg
     2341 atagaaaaga aggctttaag gcacaatgtg gttttggtct tcaaggtgtt tgctgtagaa
     2401 tatgtggaat gggaccatgt agaataagcc ctaagactcc aagggggtta tgtggagcag
     2461 atgagcatac tatagtaggt agaaactttg caagaatggt tgctggtggg acagctgccc
     2521 attcagacca tgctagagat atagcacata cattagcatt agctgatcca aatggaaact
     2581 ataaaataag agacgaagct aagttaatta ctttagctaa agaatgggat gtagagacag
     2641 aaggtagaga tatctatgat gtagcacatg aagtggcaga aattgcatta atggaatttg
     2701 gaaaaccttt tgggacatta agatttataa aaaatgcacc agaaccaaga caaaaaatat
     2761 ggaaagaata cgctatagag ccaagagcta tagatagaga aattgcaaca ataatgcact
     2821 ctactcatat aggatgtact ggtgatatag atagtttaat acacatgagt cttagaactt
     2881 ctatggctga tggttggggt ggttctatga taggtactcg tctaagcgat atcttatttg
     2941 gaactccagt gccaagaaga acagaggcga atttagcagt attagaagaa aataaagtta
     3001 acataatatt acatggacat gagccagcat tatcagaaat gatagtttta gcatcagaag
     3061 agccagactt agtagcttta gctaaagaag ttggtgctga tggaataaac ttagcaggta
     3121 tgtgttgtac aggtaatgag attacaatga gacatggtgt aaaaatagca ggagacttcc
     3181 atcaacaaga acttgcaata ataactggag cagttgaagc tgtaatagtt gacgttcaat
     3241 gtatattccc tgcattagct agagttgcag attgttacca tactaaattt gtaacaactt
     3301 ctccaaaagc taagataaca ggttcaactt atattgaatt tagagaagaa caagcacttg
     3361 atgatgctaa agcaatagtt aaagaagcta ttttaaactt taaaaataga gataaatcaa
     3421 aagtacttat acctgaatta aaatcaggcg caacagttgg gtatagtgta gaagcagtag
     3481 taaatcaatt agacagagtt gtaaactctc atatagaccc agcaggaaca gttaagccat
     3541 taacagactg tttaaaatct ggagtattaa gaggagcagc tggtgtagtt ggatgtaaca
     3601 atgctaaagg agtttcaaat gaggctcacg taacaataat gaaagaatta atcaaaaacg
     3661 acataatagt agttactaca ggttgtggag cttcagcagc agctaagttt ggtttaatgg
     3721 aatctgatgc ggctgaaaaa tatgcaggta aaggtcttgc aactgtctgt aaattagtag
     3781 gaatcccacc agtactacat atgggttctt gtgttgatat aagtcgtata ctagatttag
     3841 ttggagcagc agctaattac ttagatatgg atatgtgtga ccttccagtt gtaggtatag
     3901 ctccagagtg gatgtcagaa aaagcagttg ctataggatg ctatgttgta gcttctggta
     3961 tagacactta tttaggaata atgcctccaa tagctggttc ttcaagagca gtggatatat
     4021 taactagtga attaaaagat aaagttggag ctacatttac tgtaaataca aatccaaaag
     4081 agttagcagc tacaataata gaagatatag agaaaaaacg tgttcacttt gaagcattag
     4141 ttgaagaaaa gatggcagaa aaggctgaag cttaaaaaat agtgaagtta tagaataaac
     4201 gtttttataa gaagtttctg gttgaataaa gttgaataaa gtcaaatatt aaagtaaaga
     4261 acatcaaaat ataatgaata tactgaataa ataaaatata aacaatatta aagaataata
     4321 aaactataca tgctgctttg aaaagctagt agggtaaatt taattggttc ctgtaaggac
     4381 tagctgtagt ttatttttag tgtataaaaa tatagagtat aaaaaatatt taactgtaaa
     4441 attaactact aaaaagcaaa tagtaataaa aggtggtagg gattatgaag atagcaataa
     4501 caggtaaagg tggagtaggt aaaacgactt tttcttcaat gctctctagg atgtttgctg
     4561 aagacggata cagagttgtt gctgttgatg ccgaccctga tgctaattta gctttagcac
     4621 taggttttcc aaaagaagta tatgaatcaa tagtacctat atcagaaatg aaaaaattag
     4681 tttcagatag aacagctgct tctgtaggtt catttggaaa aatgtttaag atgaatccta
     4741 aagtagacga tatccctgaa aatttctgta aagaatacaa tggagtaaga ttacttacat
     4801 tgggaaccgt agattctggt ggtactggat gtgtatgtcc agagcatgtt cttttgaaga
     4861 gactctgctc acatttaata ctacaaaata aagatgtagt ggttatggat atggaagcgg
     4921 gaattgaaca cttaggaaga ggaacagccc aaggtgtaga tgcttttata gtagttgtag
     4981 aaccaggaga gagaagtcta cagacttata gaaaagttaa gaaacttgga catgatatag
     5041 gtgtaaataa agtatttgta gtaggaaata aaattagaaa taaggaagat gaagaattta
     5101 taatccaaaa cttagaagat ggagaatctt taggatttat ttattataac caagatgtta
     5161 ttgattctga tagagctaat caatctccat atgattctag tgaaacaacg aaagaacaga
     5221 ttaaagcaat aaaagataaa ttaatgtcac ttaaggataa ataaaataga tagaaatttt
     5281 gatttgggat tttaagttgg ttaaaggtta gacataggca atagataggt aataagtaag
     5341 taattagata aataactagc tattaagttt gaatatttta atagcttagt agctagtttt
     5401 taagtaattt tacatgtata attatcttat aaaatataat ttttacatat taatacaatt
     5461 tttacaaaaa ttatatttta aatctattta ggttgtggga ggagattcag ttatgggatt
     5521 taaatctgac attgaaatag ctcaagaagc taagcctcaa gatattagag aggttgcaaa
     5581 aaaattagga ctaggtgaag atgatgtaga actttatggt aaatacaaag caaaagttga
     5641 ctacaatcta ctaaaaagag agactggtaa aaaagctaag ttaatactaa ctacagctat
     5701 aaacccaact ccagcaggtg aaggaaaaac tactactact ataggtgttg ctgatgcatt
     5761 tgctaaacta gacaaaaatg tattagttgc tttaagagaa ccatctctag gaccagtatt
     5821 tggtgttaaa ggtggagcag ctggtggagg atatgcacaa gttgttccta tggaagatat
     5881 aaacttacac ttcacaggag attttcacgc tataggagct gctaacaatc ttttagctgc
     5941 tatgcttgat aaccatattc accaaggaaa tgcacttaga atagacccta agaaaataac
     6001 ttggagaaga tgtgtagaca tgaacgatag acaacttaga aatatcgttg atggtatggg
     6061 taaaaaaggt gatggagcag ttagacaaga tggattcgat ataactgttg cttctgaaat
     6121 aatggcagcg ttctgtttgg caagtgatat atctgattta aaagaaagat taggaaacat
     6181 aatagttgga tacagctacg aaggtgaacc tgtaacagct agacaattaa aagctaatgg
     6241 tgctatggct gcattattaa aagatgcttt aaaaccaaac ctagttcaaa ctcttgaagg
     6301 aacaccatca tttgtacacg gtggaccatt cgcaaatata gctcatggat gtaactctgt
     6361 tatagctaca agaatggcta tgcactttgc agattatgta ataactgagg ctggtttcgg
     6421 tgctgacctt ggagcagaaa aattcttaga tataaaatgt agaatggcaa acttaaaacc
     6481 agatgctgtt ataatagttg ctactgtaag agcattaaaa tacaatggtg gagttgctaa
     6541 agcagactta aataacgaaa acctagaagc tcttgaaaaa ggacttccaa acttattaaa
     6601 acatgttgaa aacataactc aagtatatgg attaccagca gttgttgcaa tcaacagatt
     6661 cccacttgat actgaagctg aacttaaact tgttgaagac aagtgtaagg aattaggtgt
     6721 taatgttgct ctttctgaag tatgggcaaa aggtggagaa ggtggaattg cagtagctaa
     6781 agaagtttta agattattgg atgaagaaga aaataacttt agattctgct atgaagatga
     6841 tttatctata aaagacaaga taaatgctat agctactaag atttatggag cagatggtgt
     6901 agattatact cctgaagctg ataaggaaat agctaactta gaaaaacttg gatttactaa
     6961 agttccagta tgtatggcta agactcaata ttctttaact gatgaccaaa ctaaattagg
     7021 tagaccaaca ggatttagaa taactgtaag acaagcaaca atttcagcag gagctggatt
     7081 tatagttgca cttactggag aaataatgaa gatgccagga ttaccaaaag ttccagcagc
     7141 agaaaaaata gatgttgatg aaaatggagt aatagctgga ttattctaag gaaattaatt
     7201 tataaataaa gagtaggaga tatcttaaaa tagttcgtaa aatatctcga acaatttgag
     7261 atattttcct acatcctttc aaggaggatt atcatgaaaa tagcagataa aacttgtgtt
     7321 gattttgtag aagtactatc ttccaaagaa gcagtaccag gtggtggggg agctgctgca
     7381 ctagtaggtg caataggtat ggctttaggt agtatggtat gtaaccttac aatagggaag
     7441 aagaagtatg ctgagtatga agaaagtgta aaagagatat taagtaaggc aggaaagtta
     7501 gaaaaagatt tattaaaaat gatagatgat gatgcagaat gtttcttacc attatcaaaa
     7561 gcttacgggc ttcctaaaga aacagaagaa gaaaaaagaa taaaagcaga aacaatggaa
     7621 aaggcattaa aagttgcttg tgaagtacca ttaaacatag taagagtttg ctatgaagct
     7681 attaagttac atgaagattt agttgataaa ggttcaagac ttgctataag tgatgttggt
     7741 gtaggagttc agtgtttaag agctgctata cttggtggac aattaaatgt agttataaat
     7801 ataaattcta tacaagataa agaatatgtt aataaggtaa aaacagaagt agataagtta
     7861 gttgaagatg gtgtaaaaat ttgtgatgaa gtttatgcca aagttgaaaa agctcttgga
     7921 aaataatttt taaatgacga aagtagatac tatgttatta atatgtggta tatagaataa
     7981 attaatttaa gtttgcttgt aggggagttg tgaatgtatg gaaggaatgt caactaaagg
     8041 acaaattata aaaggaaaac ctgtagctga taagattagt gaagaattaa taaaagaagt
     8101 cgatttacta attaaagaag gtataaatcc taaactaaca atagttagag ttggggcaag
     8161 aagtgatgat ttatcttatg aaagaggagc actaaagaga tgtcaaaaca taggtataac
     8221 aacagaagtg ttagagttag ctgaggatat aacacaagag gaatatattg atgtattaaa
     8281 gagagttaat gatgacaaaa atgttaatgg tatattatgt tttagacctc ttccaaaaca
     8341 cttaaatgaa gaagttataa aatatgttat tgcaccggaa aaagacgtag attgttttag
     8401 tccaataaac tctgctaagg taatggaagg ggataaaagt ggatttccac catgtacacc
     8461 tacagcagta gttgagatat taaaacacta taatgttgat ttaaaaggaa gtaaggtaac
     8521 agttcttgga agatcaatgg tagttggaaa gccagtatca atgcttttat taagtgaaca
     8581 cgcaactgtt acaatatgtc attcaaaaac taaaaatcta tcaggtgtag cagcagaggc
     8641 agacgtgcta atagcagcta ttggtagagc taagatggtt gatgaaagtt ttgttaaaga
     8701 tggagcggta gttatagacg ttggtataaa tgttgatgaa gaaggaaatt tatgtggaga
     8761 tgttgataca aatgcagttt tagacaaagt atcaatgata actccagttc cagcgggggt
     8821 tggttcagtt acaacatcta tacttgcaaa acatgtagtt aaggcttgta aattacaaaa
     8881 caataaatag atatatatat gtggaaggtt taggggggaa gtagatatga taatttctga
     8941 aaataaacca ttagaagaag tgctagggta cttaaaagat tttgacaagc tggttttagt
     9001 tggttgtaat caatgtgcag caacttgtaa aagtggtggg gaagaagaag ttttaaaaat
     9061 gaaggaaact cttgaaggtg aaggcaaaaa aatcttagga tatgtaatgc ttgaccctgc
     9121 ttgtaacctt ttaaagtcta aaaaggattt aaaggctcta aaagaagaga ctaaggaagc
     9181 tgatgcagtt ttatctttag catgtggaga tggtacacag acaatagtta agaatttaaa
     9241 agataagcca gtttatccag ccaacaatac tttgtttata ggggaagtac aaagagttgg
     9301 agaatatgaa gaagcctgta aggcttgtgg agactgtgaa cttggttgga caggtgggat
     9361 atgtccagta actatgtgtg ctaaaggtct tatgaatggg gcttgtggtg gagctaaaaa
     9421 tggtaagtgt gaagtaaact cagagaatga ttgtgcttgg ataaagatat atgaaagact
     9481 agaagctata ggacaattag ataacttagc agaaataaga ccaccaaaag actattctaa
     9541 gcaaaataat ccaagaagtt taagtgcaaa gaaaaagaaa gaagcagcag caaattcata
     9601 aaagtttttt ttagaaggtt aaaaggggga ttagagatga gcttattaag agaaacatta
     9661 gaaagtggaa aatttgcagt tactactgaa atggctcctc caaaagggac tgacctttca
     9721 catttaatag aatgtgcaaa gccgttagtt ggaagagttc atgcagcaaa tgtaacagac
     9781 tttcaatcgg cagttatgag agcaacttct cttgctacat gtaaattatt aaaagatgct
     9841 ggattagagc cagttattca aataacaggg agagatagaa atagaatagc tatacaagga
     9901 gaaatgttgt cagcaggtgt atttgggata aacaatctgt tggcactaac aggagaccat
     9961 actagcgtag gagaccatcc acaagctaag ggagtgtttg atttagattc tgtggggata
    10021 cttcaaactg ctgagacttt aatggcaggt acggacatgg ctggtaataa gttaaaaggt
    10081 tctccagatt tttatctagg agcatcagta actccagaat attctccaat agaagttcaa
    10141 ttattaaaaa tgaaaaagaa aataaaagca ggggctaaat ttttccaaac acaagcactt
    10201 tatgacataa atacaatgag aaagtttaga gaattaacaa gggatatgga ttgcaaggta
    10261 ttagcaggaa tagtaccttt aaaatcacca ggaatggcta aatttatgac tgcaaatgta
    10321 ccaggaatat ttgttccaga tgaacaaatc gaaagattaa gagcagctgg aaaagaaaac
    10381 tgggtaagtg aaggaataaa aatggcaggg gaacttatca aacaattaaa agaagaagat
    10441 ttatgtgatg gtgttcatat aatggcaatt ggggcagaag agaatatacc tgctatactg
    10501 gatgccgcag gtttatagta ttgcaagatt gtagattata ttaggtttgg gggaattaaa
    10561 gatgaagata gtagtagtag gtggtggacc aggaggatat gtagcagcta taaaagcttc
    10621 tatgcttggt gcagatgtaa cagttgttga aaaaagaaga gttggaggaa cttgcttaaa
    10681 tgcaggatgt ataccaacta aagcacttct tgcttcttca ggagtattga atactgtaaa
    10741 agaagcaaag gattttggta tagaaataga tggtacagtt aagccaaact tcactgccat
    10801 aatggaaaga aaaaataaag ttgtaaacca attaataagt ggtatagagt tcttatttga
    10861 aaaaagagga gtaaacttag ttaatggttt tggaaaatta attgataaaa acactataga
    10921 agtaactaaa gatgatggaa cagtagaaac tataaaagca gataagataa tactagcaaa
    10981 tggttctgtt ccagttgtac caagaatgtt cccatatgat ggaaaagttg taataactag
    11041 tgatgaagtt cttggacttg aagagatacc tgagtctatg ttaatagtag gtggtggagt
    11101 tataggatgt gagatagggc agttctttag agccttagga acagaagtaa ctatagttga
    11161 gatggttgac caaatactat taaatgaaga caaagatgta gctaaacaac tacttagaca
    11221 atttaagaaa gataaaatta aggttattac aggtattgga gtacaaactt gtgaagtagt
    11281 tgatggtaag gctgttgcaa ctctttctaa tggaaaggtt atagaagcac aatatgcatt
    11341 agtatgtgtt ggtagaagac ctaaccttga caattctgga gtagaagata taggaattga
    11401 aatggaaaga ggaaaagtag tagttaatga acatcttgaa actaatgtag aaggtatata
    11461 cgcaataggc gatataatag atactccttt cctagcacat gttgcttcta aagaaggtat
    11521 cgtagcagtt gaaaatgctt taggtaagac taaggtagta gattatagag caattccaag
    11581 atgtgtttat actgaacctg aagttgctgg tgttggtaag actgagaagc aacttgaagc
    11641 tgaaggtgta gaatacaatg taggtcaatt tgattttaga gggcttggaa aagcacaagc
    11701 tataggacat ttccaaggat ttgtaaaagt tatagctgac aaagaaactg ataagataat
    11761 aggtgcagca gtagtaggac ctcatgctac agatttattg acagagttgt cacttgctgt
    11821 tcatctagga ttaacagtag aacaagtagg ggatgcaata catccacatc cgagtttatc
    11881 tgaagggcta atggaagcac ttcatgatgt acatggagaa tgtgttcatt ctgtacctaa
    11941 attataatag acagacagag tacataaggc tctgtggcta gatttaaggg ggaagtctta
    12001 aaatgggata caatatagct gttgcaggaa aaggtggaac tggtaaaaca agtctcacag
    12061 ggcttttgat tgattatttg gttaaggaca aaaagggacc agtattagtt gtagatgctg
    12121 atgccaatgc taacataaat gaagtattag gtatcgaagt tgaagcaaca ataggagaaa
    12181 taagagaaga agtaaatcaa agagaaaagt taggcaatgc attccctggt ggtatgacaa
    12241 aggcacaata tcttcaattt agattaaatt ctataattga agaaggcgaa ggatatgact
    12301 tattagtaat gggtaggtca gaaggtgaag gatgttactg ttttgtaaat gggatactta
    12361 gagaacaagt aaacaaaata tctggtcatt acaaatactt agtcatggac aacgaagctg
    12421 gtatggaaca tctaagtaga aaagtcacta gacatgttga tacactttta ttggttagtg
    12481 attgctcaag acgtagcata caagctgttg ctagaataag agatttagct gaggaactaa
    12541 agttaagtgt tggaagaata cttttgattg taaataaagt tccaaatggg gttatgaatg
    12601 atggtgttaa agaagaaatt gaaaagcata acctagagct aatcggtgtt gtacctatgg
    12661 atgaattgat atatgaatat gattctacag gtattccttt agttaattta cctgaagatt
    12721 caaaatctaa agtggctatg aaagaaattt ttgctaaatt agaattaaaa taggcttaag
    12781 ggggaaaaaa atatggcatt taaaatgtct actcaaaaat attctggaaa aatatcagaa
    12841 gttgaagtag gaatagggga aaaagcaatt aaattaggtg gggaaaatgt attacctttt
    12901 tatagttttg atggagaagt aggtaattct ccaaaaatag ggatacaaat atcagacgtt
    12961 tatcctgaaa gctggactga ttcatataag gaattataca aagatgtagc taattgtcca
    13021 gtagagtggg ctaaatatgt tgaagctaat acacaagcag attttatttg tttaaaattt
    13081 gatggttctg acccaaatgg attagataag tcagttgatg aatgtgctga tgtagctaag
    13141 gcagtaattg aagcaataaa attaccttta gttgtagctg gttcaggaaa tcatgaaaaa
    13201 gatggtaaat tatttgaaaa attagctcaa acattggatg gacataactg cttatttatg
    13261 tcagcagtag aagataacta caaaggagta ggagcatcag ctggtatggc ttatgcacat
    13321 aaagtaggag ctgaatcttc tgttgatata aacctagcta aacaattaaa cgtattgtta
    13381 actcaactag gcgttaaagg tgaaaatata gttatgaatg ttggatgttc agcagttggt
    13441 tatggatatg agtacgttgc atctactatg gatagaatta gacttgcagc atttggtcaa
    13501 aatgataaga cattacaaat gcctatcata acaccagtag cttttgaagt aggtcatgtt
    13561 aaagaagcta tagctccaat agaagatgag ccagattggg gttgtccaga agaaagaact
    13621 atagcaatgg aagtttcaac tgcagcaagt gttttagtag gtggttcaaa cgcagttata
    13681 cttcgtcatc caaaatcaat agaaactata aaagaattgg ttaacgcatt agcttaatta
    13741 aattgttaag gttaggggga aaaaataatg gcattaaaag ctttagatat atttaaatta
    13801 acaccaaaga aaaactgtaa ggattgtgga ttcccaactt gtatggcttt ctctatgaag
    13861 gttgcttcag gagctgtaga agtaggtaaa tgcccacata tgtctgatga cgctatagca
    13921 aaattatcag aggctactgc acctttaatg aaagctttaa aagttggtgc tggtgcatct
    13981 gagtatgaac taggtggaga aacagtatta tttagacatg aaaaaacatt agtaagtaga
    14041 aatagatatg cagtttcatt ctgtacttgt atgagtgatg aagcagtaga tgctaaaata
    14101 gctaacatga aaaaagttga ctatgtaaga attggtgaac aaatgaaagt tgaaatggct
    14161 gttttagagt attgtggaga taaagatgcg tatttaaaat taatagataa aataaaaggc
    14221 agtggattag aagtagctta tattttagct tgtgatgatg cacaagtagt taaagaagct
    14281 gttgaagtat taaaagatgc tagaccaatg gtatatggag caactaaaga gaactacaaa
    14341 gatatgatag aagtagttaa aggagcaagt ttaccattag gtgtaaaagc tggtagctta
    14401 gaagaattat atgaaacagt tgaattaatt caagctgctg gatataaaga attagtatta
    14461 gatgtaacag gagaaaacat aaaagatact tacactaatg ctatacaagt tagaagaaca
    14521 gctttaaaag agcaagatag aacatttgga tatccttcaa tagtatttgc aaatagatta
    14581 tctaattcaa accctatgat ggaagttgct ttatcatcaa tattcactat aaaatacggt
    14641 tctataatag taatagatga tattagttat gctaaggcat taccattatt tgcactaaga
    14701 caaaacatat acactgaccc acaaagacca atgagagttg aaccaaagat ttatccaatc
    14761 aacaacccag atgaaaattc tccagtatta gttactgttg actttgcatt aacttacttc
    14821 atagttgctg gtgatataga aagatcaaaa gttccagtat ggttagtaat accagatgca
    14881 ggtggatatt cagttcttac atcttgggct gctggtaaat ttggtggaaa ctcaatctct
    14941 gctttcatta aagaaagtaa ggtagaagaa gtaactaatt gtaaagacct tatcattcca
    15001 ggaaaagttg cagtacttaa aggtgatata gaagataact taccaggatg gaatgtagtt
    15061 ataggaccag aggaatctat ggaattacct aagttcttaa aaggatacca agaaaaagca
    15121 tgccaaacaa actaataaaa tattaactaa ctattaatat taaatttaaa gggggacatt
    15181 ataaatggaa aaatttatga ttataggtga gagaatacat tgtatatcac cttcaataag
    15241 aaaagcatta gcagaaagag acccagctcc aatcttaaaa agagcaaaag agcaattaga
    15301 agcaggagca cactatatag attttaatat aggacctgcc gaaagagatg gcgaagaaat
    15361 aatgacatgg ggaatcaaat tacttcaatc tgagttcaac aatgttccta tagcattaga
    15421 tacagctaat aaaaaagcta tcgaagctgg acttaaagtt tatgatagaa ctaatgcaaa
    15481 accaataata aactctgctg atgctggctc aagatttgat ttaatagata tagcagctga
    15541 atacgaagca atggttatag gtttatgtgc aaaagaaggt atcccaagag ataatgatga
    15601 gcgtatggct tactgccaag aaatattaga aaaaggctta atgttaggaa tggagccaac
    15661 tgatatacta tttgacccat tatgcttagt tataaaaggt atgcaagaaa aacaagtaga
    15721 agttttagaa gctataaaaa tgatgactga gatgggactt ttaactacag gaggattatc
    15781 taacgtatct aatggatgtc ctaagcatgt tagacctgtt ttagatagtg cattcttagc
    15841 aatggcaatg gctaatggat ttagttcagc tataatgaat ccatgtgacc cagaattaat
    15901 gaaaactgta aaatcttgtg acataatcaa cggggcatct ttatatgcag actctttctt
    15961 agagttaaat gaaggtggat ttgctttcta gggtttttag ggtatagtta ataaaaaata
    16021 ggtgtaaata ttaaaggggg aaatagaatg aatctatata atataatctt tacagggtca
    16081 gaacaagctt taggtgcggc tcaagctatg ttagctgaag ctatagaaaa gaatggaaaa
    16141 gagcataaag ttgctttccc tgatacagca tattcattac cttgtatata tgctgcaaca
    16201 ggacaaaaga tgaacacttt aggggactta gaaggtgctt tagaagtagt aaaatcttta
    16261 ataaatagaa ctcatttact agaacatgct tttaatgctg gtttagctac agctttagca
    16321 gcagaagtaa ttgaagcatt aaaatattca actatggatg ctccatatag tgagccatgt
    16381 gcaggtcata taactgaccc tataatcaga tcacttggtg taccattagt tacaggagat
    16441 atacctggtg ttgcagttgt tcttggtgag tgtccagatg cagaatcagc agcaaaagtt
    16501 ataaaagatt accaatctaa aggtttacta actttcttag ttggtaaagt tatagaccaa
    16561 gctatagaag ctggagtaaa aatgggtctt gagctaagag ttatacctct aggatatgat
    16621 gtaacttctg ttatacacgt tgtatctgtt gcagtaagag cagcattaat attcggtgga
    16681 ttaactcctg gtgatttaaa cggattatta gagtacacag ctaatagagt tcctgcattt
    16741 gttaatgcat ttggaccatt aagtgaatta gttgtatctg caggtgctgg agcaatagct
    16801 ttaggattcc cagttataac tgaccaaaca gttcttgaag ttccaatgaa cctattaact
    16861 caaaaagatt acgataagat agtagctact tcattagaag ctagaggaat aaaaataaaa
    16921 gttactgaaa tacctatccc agtttcattt gcagcagcat ttgaaggtga gagaattaga
    16981 aagagcgata tgtttgctga gtttggtgga aacagaactg aagcttggga gcttgttgtt
    17041 aagaaagaag caacagaagt tgaagaccat aagatagaaa taataggacc aaatatagat
    17101 gaagttgatg cagatggtgt attaagatta ccacttgctg taatagttaa aatagctggt
    17161 aaaaatatgc aagaagattt cgagccagtt cttgaaagac gtttccacta cttcttaaac
    17221 tatatagaag gtgtaatgca cgttggacaa agagatatgg cttgggtaag aatctctaaa
    17281 gatgcatttg ataaaggatt tagacttgag catataggag aagttttata tgctaagatg
    17341 ttagatgaat ttgaatcagt agttgataag tgtgaaataa ctataattac agatgctgaa
    17401 aaagtttctg aattaaaagg tgaagcaata gctaagtaca atgctagaga tgaaagatta
    17461 gcttcattag ttgatgaaag tgttgacact ttctattctt gtaacttatg tcaatcattt
    17521 gcaccagctc acgtttgtgt tgttactcct gaaagacttg gtctttgtgg agcagttagc
    17581 tggttagatg ctaaggctac taaagaacta gacccaacag gtccttgtca accaatagaa
    17641 aaaggcgagt gcttagatga tagaacaggt gtatggaatt cagtaaatga aactgtaaac
    17701 caaatatctc aaggtgcagt tgaatctgtt acattatatt ctatactaga agacccaatg
    17761 acttcttgtg gatgcttcga atgtatctgt ggtataatgc cagaagcaaa tggatttgtt
    17821 gtagttaaca gagaatttgc aagtgttact ccagttggta tgactttcgg agaacttgct
    17881 tctatgacag gtggaggagt tcaaactcca ggatttatgg gacacggaag acatttcata
    17941 tcttctaaaa aattcgctta tgcagaaggt ggaccagaaa gaatagtttg gatgccaaaa
    18001 gaattaaaag attatgtagc tgataaatta aatgctacag ttaaagaaat gactggaata
    18061 gaaaacttct gtgatatggt ttgtgatgaa actatagctg acgattctga aggagtatta
    18121 gctttcttag aagaaaaagg tcatccagca ttagctatgg aaagtgtaat gtaattgatg
    18181 gaaaatttaa aataatatga tataatatta atatgattta agtaatttaa tcaataatat
    18241 aatattgggg gtctatcgaa atgaaattat taccagaatt aaaatactct aaagatcatg
    18301 agtgggtaaa agtaattgat ggagatgttg tatatatagg tataacagac tatgctcaag
    18361 atcaattagg agaaatattg tttgttgaaa caccagaagt agaagatact gtaactaagg
    18421 gagtagattt tggagtagtt gagtcttcta aagtagcttc tgatttaata tctcctgtta
    18481 atggtgaggt attggaagtt aatgaaaaat tagaagatga gccagaatgt ataaatgaag
    18541 acccatatga aaactggata ttaaaagtaa aactagctga tgtggctgaa cttgatacgt
    18601 tattaagtga taaagaatac gaggctggat tagaataatt aaagattaag atattattat
    18661 aattggggaa agtatagtag aatttgagtg cacgcaaatt tagctatact ttccttttat
    18721 catatataga acaaattggg agggataaca tgataaaagt aagttttaca ccaaacaata
    18781 aagaggttta ttgtaatgag ggggatatat tactagaggt tgcaagaaat gcagatatat
    18841 tcatagatgc tccttgtaat ggaaacgtgt cttgtgggaa gtgtaaagta aaattattga
    18901 atggaaaagt tgatacagaa aaaacaagac atataacaga tgatgagtgg gagcaaggtt
    18961 atatactagc ttgttgtaca aaggtaatat cagatataga aattgaagtt ccttctaaag
    19021 tatcatcttc tatgcatggt atgaagatag aaggtagtaa taaaaaagag gatagggaaa
    19081 tttttgaaag agctaaaaaa ataattgaag aacataacct tcaatttaaa acaaatataa
    19141 aaaagaaata catagaaatg gaagaaccaa atttagatga taatataagt gatgtagata
    19201 gattggaaag atatgttaga aataacctag gatataatga aatagatttt agattggata
    19261 tacttagaaa aatgccaact gtatttagaa agagtgattt taaggttaca ataacatatg
    19321 ttcaaaaaca aaagaaactt acaatcataa atatagaaca aggaaataaa gaaaattcct
    19381 tatacggagt tgcaatagat attggtacaa cttcagtagt tgtttgttta gtagacctat
    19441 actcaaaaga ggtagtagat aaagcatctt ctggaaatgc acagataaaa tatggagcag
    19501 atgttataaa tagaattata tattcaacta agaaaaatgg attagagaca cttcataaag
    19561 ctatagttga ggaaactata aatccactat taaaaacaat atatgaaaga aatggaatag
    19621 ataaggaaga tgtagttaca ttagtggctg ccgggaatac aactatgaca agtttattct
    19681 tgggtgtgta tacagacttc ttaagacaag aaccttacat accaccattt ttaaaatctc
    19741 caaaacttat gggtgaaaat gttggtcttt ttgtaaatga cagtgcatat gtgtacttag
    19801 ctccatctgt tgcaagttat gtaggaggag atataacagc aggtgtatta tcagcaggga
    19861 tatggtcaag tgaagaaaat gttttattta tagatttagg aactaatgga gagattgtat
    19921 ttggaaataa agattatatg atgagctgtg catgttcagc aggacctgct tttgaaggtg
    19981 gagggataag ctgtggaatg agagcatcag caggagcaat agagaaagta attattgata
    20041 aagaaacttt agagccaaca ttaaagatta ttgatgaatg tgcaccagtt ggtatatgtg
    20101 gttctggtat aattgattta atctgtcaaa tgattaccaa aggtgtaata gatagaagag
    20161 gtaaaatata cagggattta gataataaga gagttagatt taatgagcat gagataggag
    20221 agtatgtatt agcatttaaa gaagaatttg atttagaaaa tgatatagta gtcaatgaag
    20281 ttgatataga taatttcata agagctaaag gagctatata ttcaggcgca tacactcttg
    20341 tagatagttt aggtatggat tttagtatat tagatagggt ttatatagca ggtggtatag
    20401 gaaacaacct agacatagaa aactcaataa ttatagggtt acttcctgat attgatagag
    20461 aaaaatttac ttatataggg aatagttcac ttgttggttc ttacttagct cttataagta
    20521 aagatgcaaa aaataaactt gaagaaatag gtaatcaaat aacttatgtt gaacttagtg
    20581 tatatccaag ttatatggat gaatttattt ctgcatgttt cttaccacat acgaatatag
    20641 agcagttccc aacagcaaag aaattactag aagagtaaaa tgtacttaag aaggaataaa
    20701 ctatgaataa gaatctatct gaaaaaatga aaatagcatt tgatattaaa ttaaagaatt
    20761 ttggaaataa aatagagttt gcttatccta accagacact agctcttagt actacaagca
    20821 atcaatgtag tttgaaatgt gcccattgca acggtcacta cttaaacaat atggtgccaa
    20881 tagaagaata tgaggaaaaa gtacaatcaa ggaatataac tagctttcta ttgagtggcg
    20941 gttgtagtta tgagggagat gtccctataa atactcatat taataccatt aaaaacttaa
    21001 aagagcaagg atatagattg aatgctcatt taggtcttat ggataaagat agcattgtag
    21061 agttgtgtaa gtatttagat atagtttctt ttgatttagt gtttgatgat gagacaataa
    21121 gagaagttta taagatgaaa aagagtaaag aagattatat tgaagtctat aatacaatac
    21181 aagaacatac agaagtagca ccacatatat gtattggttt aaaaggagga caaataaagg
    21241 gtgaatatga aattatagaa tacctacaaa aaaatcctcc taataagctt acatttatag
    21301 tccttattcc aacaaaaggg actgagtatg aaaatgtaga acctcctgag ttagaagggg
    21361 tagcagatat tttatgtgaa gctagaatta atttaccaga tactgaaatt aatctaggtt
    21421 gtatgagacc aagaggagtg tatagaaaag agctagacca attatctata atgtgtggag
    21481 tcaatagaat agtattacca tcaaggtctg caaagaataa ggctatagaa atgaatatga
    21541 caataaatga gtgtaaggag tgttgcgttt tatgattaga ctatcagttg ggacagcaat
    21601 agaacttggg atattaaaca aaaaaagcga tatacctcct accacagcat atataatgat
    21661 tggagaaaaa tgcataaata aatgcagttt ttgttctcaa tcaatagaaa gtagtactag
    21721 aaaagataaa ttatcaagag taatttggcc agagttttca aaagaagaaa tattagatgc
    21781 tttaaaagct tataaaggaa aaaatataaa gagaatatgt attcaatcaa tggcaagtga
    21841 agaagcacat aactctgttt tagactttat aaactatata agtggtaaga tagacatgcc
    21901 aatttcacta tctgcaaaat tagaaaatga tgaacagata aagaagtttt tttcagcagg
    21961 agtaaataaa ataggaatag caatagatgc agcaaataaa gaactatatg aaaaaataaa
    22021 aggaaataac tatgatgaaa agttaaaatt tataactgaa atgtcaaaat catatcccaa
    22081 taaaataagt acacatataa tagttggtat gggtgaaagt catgaagata tatacaattt
    22141 atatacttat ttaaaggaaa atgatgtaac gattagttta tttgcattta ctccagttag
    22201 aggaactaaa atggaaaaga taagtcaacc aagcatagaa agttatagaa gggtacagtt
    22261 aatgtcttat atgataaata aaggttatcc aaaagagtat tttaagttta aaaatggata
    22321 cttaaatagt ataaagcttg acaatgatat tttaaaagac ataaacaaag gctatccttt
    22381 tgaaataaga ggttgtaagg attgtaatag accatactat aatgaaagac caggaagtac
    22441 tatatacaac tattcaagac ctttaaatca aagtgagata gatttagcaa taagagaaat
    22501 aaatctatag aggatttcta ggatatattt atactaaaaa tgggggcgta ataatcatga
    22561 atcagtggag agttatacat aataaatcat atgaaggagc aatgaatatg gcaattgacg
    22621 aagctatatt tactgcatat aagaaaggac ataataagcc aactcttaga ttttatacat
    22681 gggaaccagc ttgtttgagt ataggatatt ttcagaaatt ggaagatgag atagatttag
    22741 ataagtgtag atgtatgaat atagactata ctagaagaat tacaggtgga agagctgtat
    22801 tacatgataa tgagctaacc tatagtataa ttataggaga agataatcct ttaatcgata
    22861 agagcatcaa cctatcttat agatatataa gtgaaggtct agttaaagga ttgaatctaa
    22921 gtggtataga aacagataat ttaaatagag gcgagagaat aagtagggaa aatttatcag
    22981 ctgcatgttt taatgcacat gcatcatatg aagttactat taataataag aaggtaattg
    23041 gaagtgctca aagcagaaaa gatggtgttt tattacaaca tggttcaata atactggatt
    23101 ttgatgtaga aaaattgttt aaattaataa aaactaagac gccagaattg aaagaaagag
    23161 ctatgaaatt tacagctaaa aaagcaagtg gaatagaaaa tgaaattggc agaaaaatag
    23221 acatagatat tctacagaaa aacatagtaa agggattagc tgaacaattt aatgttgagt
    23281 ttgtggaggg cgatttgact gattatgaga agcaattagt taaagaacta tatgaaaaat
    23341 acaagaatga agagtataat aaaaagcgtt aactttaatt gactttacat aaattaaagt
    23401 gatatactta aggtataata atatacaaaa actgaaatca tgaaggtttc tttggtgtat
    23461 tgaaatacct aagggaatct ttttttgatt tttaataaaa atcatattag gaggagattt
    23521 atatgtgtga atcatcagct ttcatttgta aaagtaataa tgagttagaa aaggttatgg
    23581 aaaatgtggt taatatagac ccttgtgatg gaaagattta tttaacggat ttattaggag
    23641 agcaaaagat aatagatggg ataattaaag aaataagatt gatggaccat aagatcataa
    23701 tacaagaaaa ttaattaata ggggaatttc atatgataat agcagtgata gatggaatgg
    23761 gtggaggtat tggagcccag atagtttctt ctttgagaga agagttacct acatatgtag
    23821 aaatttatgc actagggact aattctatag caactagttc tatgatgaaa gctcatgcta
    23881 ataaaggagc tacaggggaa aatgctatag tagtatcagc taaaaaagca aatataatag
    23941 ttgcacctat ttctgtaata atacctaatt ctatgatggg agaagttact tgtaatataa
    24001 gtgaagctat tgcagacagt gaggcactta agatactttt acctattatg ccagaaaatg
    24061 tggagttagt tggattagaa ggtaaaccat tagcactact tgtaaaagat tctgtaaacc
    24121 ttataaaaaa agagtttaat ataaaataac agggggaata actaatgatt tttgataaag
    24181 agattgtaag atatcatcat ggacatcatg accatgacca ctgccacgaa catactcatg
    24241 gagatatatg tcatgaacat ccacatgacc atgctcacga ccacgaccac gaacatagtc
    24301 atgaggaatc atcagagtct aaggatgaaa aaactttaaa aatactttta gtacattgga
    24361 taaatcacaa tgaaactcat gaagaaggat ttagagagtg ggttgaaaag gctagagcta
    24421 ttggaaaaga agaaacagca aagagtattg aaaaggctat agagtatatg gaagaagcta
    24481 ataaaatgtt gttagaggct aaaaaacata tgtaaatata attaatcgct tatacgtttg
    24541 atataagcga tttttatatt ttgtgatgct taattattaa aaattttatc taaggggttg
    24601 tctaaagatg gatataagcc tccctttcat tgttgaaatg ataaaaatat atctaatttc
    24661 atgcaaaaaa gagtatatca tgaactaaaa agtttatttt gaggtatttt ctgtaatata
    24721 ctttaatgag taaattttat tacaaggttg gattatttaa tgttagataa ttatatattc
    24781 tttaaatact gcaaaagcct catcaagcaa tttgagttat ttgatgctaa gtaattatat
    24841 attgagtatt actatttaaa gatagtatta atgttaagtt aaaaaataat attaatgtta
    24901 agttgaaaat agtactaatg ataagatact taaaaggcag tttaaaatta ctctaatatt
    24961 agatataata aaaattagca tgattaaaaa tattattttg aagttaaaaa atttatgcat
    25021 ttatattaga ttttttcttt aaaaaaggag tgaattattt atgaaagatg gtcatataca
    25081 ttcaccttat tgtcctcatg gaagtaagga tgattttgaa aaatatgtac aaagagcaat
    25141 ggatgttgga ataacagaaa tgacatttac agaacatttt ccgtatgcaa atggatttag
    25201 agaccctgct cctgaaaatg atagttgtat gagtattgaa gatttaccaa agtattttaa
    25261 tgatgtcaag aagttgaaag aaaagtatga gggtaaaatc aagataaatg ttgggtcgga
    25321 agtggatttt atagaaggat acgaagaagg gataaaggag aatttaaata aatatggaga
    25381 agaattagag gattctcttt tatcagtaca tataattaag attgatgatg attattattg
    25441 tgtagattac agtgtagagg agtttcaaaa tttaatcgac aaattaggaa gtattgaagc
    25501 tgtttataat aagtattatg aaacattgat aaaagctgta aattcagatt taggtataca
    25561 taaaccaaaa agaataggtc atttaaattt agttagaaag tttaatcagg tatttccata
    25621 cgattataaa ggaaataaaa ttcttgaaga gttaataaag ttaattaaag aaaaaggtta
    25681 tgaacttgat tataatgttt ctggaaatag aaaagagtac tgcaaagagc cttatataga
    25741 tggatactta ttagacttgg taaaaaaata cgatattcca ttagttttag gttctgattc
    25801 tcactgtgca gaggaaataa ataaatacga tattatttag atatattcac acaaaagact
    25861 gtagataagt ttgtataaaa taaatttatg tacagtcttt tgtaaattta tatgattgaa
    25921 aatagtaata gaacttaaac aaaataataa taagttctaa gtaaaataac aatagaatct
    25981 aaataaaata ataataaaat tcaatagaat aataggactt agaattaatc tatcttattt
    26041 atataaacat tcttatataa gattgtagat aagcttgtat ttacacaaat ctatagacct
    26101 tctctattat attgacttag taattataaa tactattttg cgtttaaagt tattatttca
    26161 taagtttatc gttttccatt attatagggt caggtaattc aatttcacct tctgagatct
    26221 tcaatctatt aaacatataa ttttttacat cttctttatt tttaaattta gtaacttgat
    26281 aaggtgatgt aacaccatat ttttctaaaa atagaatgcc atttttagtt ttaatacata
    26341 tgcctgtatg acctataaat acatttttag tttctggata acgaagaaat ccatttataa
    26401 tagatatatt tttattattt ttaaaagata tttttctttt tttccattca ttttttattt
    26461 gttctgcaat tttgattgta tcatctgtat ctttagctgg tattgcagaa aagaagttga
    26521 taaatttttc tacatctttg gtgctaaatt tagcatcttt attattcatt atagtgtcca
    26581 agtcgacatt caaatcaata gagtctccag taaatttctt atttgaattt ataaaatctt
    26641 taaaaagtct aaaagcagtt attctacaat ttacatccat ataatcaggg aattttttca
    26701 cccaattatc ttgcaatttt tctaggttat atggaacttg ttttgcattg attgaagaat
    26761 atccagattt agatatattt atattatttt gaagtatttt aacttgcaat ttattataat
    26821 tgttgactgc tttaataaat gtatctatgt ctttttcatt aattttattt tcttttagga
    26881 tttcctttac actattttga gtttttttat ctatcatatt agaatatatc aatttgttat
    26941 tattatattt aatatttgaa tatgcaaata tcgtaagtat acttgatagt actaagacaa
    27001 cagacaatat cattattatt aatctttttt tcatatttag ttctcctttt taaatttatt
    27061 gtgtcgacat atttatagta tatagtacct ttaaatttac cttcaatatg tttttaatta
    27121 caaaactgtt gtaaaaaata taactttatt taaaactttt ttttaatatg taaatatata
    27181 tactaatagg gggtacttat ttttagaata ttaagtaaaa tgattttgat atactctcta
    27241 tattttgtat gttaaaagta aataaattat tgttaaagaa ggtaaagact tttaaatttc
    27301 ttatcatagg attttaagta aataagaagg attggagtaa ttaaaaattt ttattttgca
    27361 aaaataagta tttatttata tggataaatt agattttaaa tctataaata tagataaaat
    27421 ctaattattt aacttcaact attcctcaaa aaagcaactt ttaaggaata gttgaagcaa
    27481 aaagtttggt tacataatag taattttagt tacaagaatg aaactgtaaa acttaggatt
    27541 ttctttatat aatttcattg agaacattta atttaggagg taagatatga aagtaaaaaa
    27601 atttaaaagt ggtatagtaa tggcattaac agtaatggca attggagcat cattgacaaa
    27661 tgtatcagct atggaattaa acaagagtaa agagtttgaa actaaataca atgaaatgaa
    27721 gatggatttt caagaggaat atggaaaaga agacaaattt aatataacat tgaatgatga
    27781 atttacaaaa gaagaagtaa atggagctaa agggattata aagacaacta ataaaatgaa
    27841 taatgaggtt gtagtattaa attattttga tgaaatgaaa tctggaattg aatttgagtt
    27901 gaagccaaaa gcagaaaaaa atgcaatttt gagagatgaa tttcaacaag gttatggaaa
    27961 ggaagataaa ttcaaagttg tgctagatga tgaatttaca aaagaagagg taaatggagc
    28021 taagggcatt ataaagacta cagataaaga gacaggtgag gttatcgtat ataattactt
    28081 tgatgagctt gaaaaataat gcttaaagat tactttgatt gaatgaaaag gtaattgtgt
    28141 tgagaatatt aaatgactga ataaaaacag ttgtatcaaa acaaacaata atagaatgta
    28201 agaatgattg tgtcgaaaat ataaaatgac tgaataaaaa acgattgcgt caaaaataaa
    28261 caataataga atgtaagaat aattatgtcg aaaatataaa atgactgaat aaaaacagtt
    28321 gtatcaaaac aaacaataat agaatgtaaa aatgattgtg tcgaaagtat taaatgactg
    28381 aataaaaaac gattgcgtca aaaataaaca ataatagaat gtaagaataa ttgtgtcaag
    28441 aatattaaat gactgaataa aaacagttgt atcaaaaaca aacaataata gaatgtaaga
    28501 atgattgtgt tgaaaatatt aaatgactga ataaaaaact attgtgtcaa aaacaaaaaa
    28561 taattaagtg taagaatgat tgtatcaaga atataaaatg attcaacaaa aaacgattgc
    28621 gtcaaaaata aacaataata gaatgtaaga atgattgtat caagaatata aaatgattta
    28681 acaaaaaacg attgtgttaa aaataaaaaa caattaaatg taagaataat tatgtcaaaa
    28741 atataaaata aattaaaaga aaaagattat actgaaggaa aaagatttga aataggggtg
    28801 aactttacat attatagttc acccttatac aaaaatataa aatataattt attataggaa
    28861 aatttaaaaa aatcagtcta tttaatttat actgatatat tgtagggttt tacaaacaaa
    28921 ctgttatata acttttttta tctccaattt tgattttaag atatctaaga atttataaca
    28981 atcttctgga tatatttctc ccatatttgc tacttggaat atgttagcgt ctaggaattt
    29041 gccttttcct ggatagacaa catagccact ttccctttct agccctaata taaactcatt
    29101 tacattgatt tctttaggta gaaatacaga tgttactgta ttagacatat acttatctgg
    29161 aagtaaaaat gttagaccca attcttccat gccattcctt aaaatagcag aacattcttt
    29221 gtatctttct attttactgt catcttccaa aaattcagtt aaagcttcat taagggcaaa
    29281 tattaaagta acattaggtg tatttggtgt ttgagaagat gatttagcaa ctttatagtg
    29341 tttataaaga ttaagataca cattcttaca ttgattttct ttaatatttt gtaaaatact
    29401 ctctttagca caaaggtatg cagaacctgg aaatgctcca agagctttgc caccaacacc
    29461 tgttattata tctatattaa actcttccac atcaatatat tcacctgctg aggcacttat
    29521 tgcatctaca aaaaatattt tgttatactt cttagcaagt tttcctagtt cagggactgg
    29581 atttatcatt cctgaactag tttcatggaa caccatagca attactttta tatcagaatt
    29641 ttcaattatg tatttttcta aaatgtctag gtccgggtat tctgcccatt caaaattagg
    29701 tttatatgtt tttacattat aagtagataa tatttcttct agcctttctc caaaaacacc
    29761 attactaact agcagaactg catcttcttt gtcaaagata gaagatagta cacattcatt
    29821 tacagatgtt ccagagccag atacaattaa tgagtagtaa ttagaagttg cattatatag
    29881 tttattgatt ttttgttgtg tatctttgaa taaatccata aactcatttc ctctatggca
    29941 tatatcatag tgaagaagtg aatttctgac tttatctgta accattactg gtccaggact
    30001 gaatagatat gtttttttca ttgtaaagcc tccttaaaaa gttaaattta aatttttgaa
    30061 tgactgatta tgtgtaaata ttaaaatgtt atgtgttatt ttaactagat tatagaataa
    30121 aataataaat attgcaataa catttcaata aaaatacttt tttaatcact ataattaaaa
    30181 ataacaaaaa atattgtaat gaatattgca taaatccaca tgatgatata aaatataaat
    30241 aacttgaata gattatatat tcaaaaaata aaaaagaatt tattaattct gaaaataaag
    30301 ggggacattt aaagtgaaat atgtattagc aattgaccaa ggaacaacag gaacaagagc
    30361 agtattgata aacgaaaaat cagagtttgt ttttagcgat tatatggaac atactcaaat
    30421 atatccacaa tctggatatg ttgaacatga ccctatagaa atttggaata atacaaaaac
    30481 tgtgagtaat aatgtattac aacaggcttt tgaaaatgga atcaatgaaa gtgatataaa
    30541 aggaattggt atagataatc aaggtgaaac agtaatgtta tgggataaaa atacaggtaa
    30601 accactttac aatgctattg tgtggcagtg caggagaact tatgattatg tggaaaattt
    30661 aaagaatata ccaggtttag aaaataagat aatagataag actgggttaa ttatagaccc
    30721 atatttctca ggtacaaaaa ttaaatgggt aatagataat gtaaaaggtg taaaagaaaa
    30781 aattaaaaat ggagaagtac ttgcaggaac attagatagt tggttaatat ggaaaatgac
    30841 aggaggaaaa tcttttttaa ctgatgtatc tacagcagca agaacaatgc tttttaatat
    30901 aagagatatg gattgggata gagagttgct tgacattata ggagtaccta gaagtatttt
    30961 agcagatata atgcctacga gtggtgattt tggaactaca gataaggagg cattttgtgg
    31021 ggtttctata aaaattactg cttcaatggt agaccaacca gcagctttat ttggcaatgg
    31081 atgttttgaa ccaggaatgg ttaaaaatac ttatggtaca ggatgtttcc tatatatgaa
    31141 tataggtgag gaactaaata tagcaggtaa tggtattttg acaactgttg cttggaaaat
    31201 aggagataaa gttacatatg cttatgatgg tggagtgtat atagcaggtg ctgcaataca
    31261 atggcttaga gatggcattg gagttataaa aaattattca gaaactgatg acatggcaaa
    31321 ttccatatca agtactggag gtgtatattt tgtaccagca tttgcaggta tagcagcacc
    31381 ttattgggac caatatgcta gaggtacaat ggttggaata acaggaagta ctaaaaaaga
    31441 gcatatagta agagcgactc ttgagtctgt tgcacttcaa gtcaaagatg ttgttgattc
    31501 tatgaactta gcctcaggga aaaaaataaa aatgttgaga gtagatggtg gaattactaa
    31561 aaataacttt acaatgcaat ttcaatccga catattaggt ataccaattg aaattgcaga
    31621 aaatcctgag acgacagtac ttggagtagg atatatggca ggtctttctt gtggtgtctg
    31681 gaacagtatt gatgaaatta gaagtgaatt tacaataagc aaaaaatata ttccaaatat
    31741 gactactcaa aaaagagaag aaatattact tggatggaac caagcagtaa aaagagctat
    31801 gaattgggaa aacgatacca aaaaggtgtg tgctaattaa gttacaatag agtattttac
    31861 atgtatagga ggaattaaaa atgccctttg ataaaattat attatacata atggctgtgg
    31921 gagtgctttt aggagcgtta gatagaataa ttggaaataa atttggactt ggtgagcagt
    31981 ttgaagaagg gtttaattca atgggtccat tggctttagg aatggttggt atagtttgtt
    32041 tagctccagt aatttcagat gtactaggtc ctataataat accaatcttc aatctctgtg
    32101 gagctgaccc atctatgttt gcaactattt tagcgaatga tatgggaggg tatccattgg
    32161 ctatggaact tgcacacaat aaagaggcag gaatgcttgc aggattggtt gtgtcatcca
    32221 tgcttggatg tacattagta ttttcaattc cagtagggct aggtcttata gaatatgaag
    32281 acagaccatt ctttgcaaaa gggttactga taggcttgat aacaatacct tttggaggta
    32341 ttataggagg attaatagca ggatttaact tatcaatggt aattataaat atgataccag
    32401 tgataatatt ggcagtaata ttggcagtag gtttaaaatt taattctacg cttatgataa
    32461 atgggtcatt agtttttgga aaatttatat ctatattgat aacgataggt ttgggagcag
    32521 cagcatttca agaaataaca ggtatagtac ttataaaagg catgacacct ataagagaag
    32581 gtattcaagt aattggaagt attgcaatcg tgttattagg tacttttcca atattacatt
    32641 tattagttaa agttcttaat aaaccactta caatagtggg tggaaaatta ggtatggatg
    32701 ccactagtgc agcaggatta gtttttactt tagccaatag tattccagta tataaaatga
    32761 tgaaagatat gagtccaaag gggaaagtag taaatactgc ttggctggtt tgtgctacag
    32821 cagctttggg ggaccattta ggatttacag caggagtagt tccagagatg attacacctg
    32881 ttgtaattgg aaaattggtt ggaggagtat tggcaattgc acttgctata cttatgacaa
    32941 aagatttaac cttggaagaa gaacaaagta ttaaaatgaa gaaagatgca gtgtagaata
    33001 aacaatactt aagtcaaatt taaattattt taaagtagga gtttaaataa ctaaaaataa
    33061 attaaaaaga cagacaatta aaaaataatc gaataactaa aacttataaa ttaaataaaa
    33121 tggcaatcaa ataactaaaa atgataagct aactgaaagt agttacataa ttaaaatata
    33181 aagtatagtt tagacataaa tggagctaaa taaataatta tttggctcct taattttaat
    33241 ttattacatc aaggaactaa aaatcaatca tataagctaa ttatcagcta tgactaaagg
    33301 tattcctttt tgagaaaact ctattattat attatggtct atactagcag aggtaataat
    33361 agtatctata tgttctatag gagctactga tgcaaatgaa tttataccaa acttaggagg
    33421 ttcgacaact actatagatt ttctagacct ttcaatcatt ttttttctaa caagtgcttc
    33481 ttctaagtga tagtcagaga ttccattttc aagagtgata cctccagcgc ctaaaatagc
    33541 tttatcaaca ttaaattgtt caatagctga cagtgtaagc ggaccagaaa aagaaccttc
    33601 agtttctcta agatagcccc caagcacata tacttttata ttagtattca taagttcgtt
    33661 tgcaactaaa attgagttgg ttattacagt tagattcttt ttatctttca aattttttga
    33721 aacttcaagt acagtagttc cagtatccat aaaaatagta tcatttgtat ttataaactc
    33781 actacattta atagcaatct gttttttatc gtttgagttt attttttttc ttttaacata
    33841 gttaagttct acgctacttg ctataactgg tatagcacca ccataaactc tttttaaaag
    33901 accgatactc tccatatggg ctaaatctct tcgtgcagtt tctattgata tgtcaaacat
    33961 ttgaactatg tcatttattt taattatatt atctgatttg agaatactta aaatcttctc
    34021 atatctttcc tgtggtaaca taaaatatcc tccttggact agtattattt tagttttggc
    34081 ataacttaca attaagtcag agtttaggta tatttgttaa tgtatgtata tttatcaaat
    34141 aatattataa gtgttatgca agataatttt accatattta aaacttacat ttaagcaaaa
    34201 aagtaaaaat agatgtttaa taattcaaaa taactcaaat tttataaaac aattgactaa
    34261 aatatgattt tattatataa tttattagta tagagatatg gagaagtact caagtggctc
    34321 aagaggatcc cctgctaagg gattaggctg ggtaaccggt gcgagggttc gaatccctcc
    34381 ttctccgcca attattaaag gctattttta ttaaagatag tctttttata atgtcataaa
    34441 tgattagata tgtataacta aagaaaggag ggaatagatg acaactttaa tttttttcat
    34501 agtggggata gcatctttgg tagttgcttt tgttattgat gggggacatg ttggagcatt
    34561 atttgtattt tcatcagcac ttgttgtgtt tggtggaact ataggagctg ttggagcttc
    34621 gactccattc cctgtgttta aaaagtctat aaagataatg ttattagctt ttaaaaataa
    34681 aaagcctaat aacatagaaa atataatcta tttcaaagaa attgcaacaa aggctaggaa
    34741 agaggggctt cttagtattg acaaagaaat aagtgagaat gatgaattag acccttttat
    34801 tagaaaaggg cttgaactta tggtagatgg agtggatgca gttactataa gaaatatatt
    34861 ggaatcacag atacagataa catcaaaacg acataaagaa ggaatagcaa tttttgattc
    34921 agcaggtgga tatgcaccta cactggggat aataggtaca gttatgggat tagtacatat
    34981 tttaggtaat ctttcaagta atccagatgc attaggacct caaatttctg ttgcattttt
    35041 ggctactttg tatggtgttg gttctgccaa tttaatatgg ttaccaatag catcaaaact
    35101 taaggctata aatcaacagg aaataagtga aagacttttg gtgatagaag caatattatc
    35161 catacttgaa ggtgataatt ctaatttaat gacagaaaaa ttaaaaatat ttttaaattc
    35221 aaaagaacta attgaacttg aagaaattgg tggtagagct gaataatata aaaggatgga
    35281 atgtttatgt tgtatgatga agatgaaaaa gaagaaaaca atgagcgatg gcttttaact
    35341 tattcagacc tcataacatt acttatgatt ttctttgtaa taatgtattc tatgagtaat
    35401 gttgatgcgg agaaatataa acaattatct caatctctaa attctgcttt tggtggttct
    35461 tctggagtta ttgaaggtgg taatagcaag atagaaccag tagttgaatc aggaagtaat
    35521 gatttagata ctttacaaaa tgctaagttt aaaaaagttg gtgaagaaat ccagaagtat
    35581 ttaaacgaaa atggtatggc taattcagta tcattaagag ttcaagatag aggattagta
    35641 ataagcctta aagatacaat actatttgat acagggaaag cgattgtgaa ggataattct
    35701 agagataaga ttattcaaat aggtaagatg ttaaatgaaa tgaatagtta catgagagta
    35761 gaaggtcata cagacaatat gtctataaaa aattcagagt ttaagtcaaa ttgggattta
    35821 tcagttatga gagcaaccaa tgttgttcaa cttcttattg acaatgcagg tatagcacca
    35881 gataaattat ctgctgtagg atatggtgag tttagaccaa tagcagaaaa ttcatctgaa
    35941 gaaggtaggt caaaaaatag aagagttgat atagttttag ttgatagtaa atatgataat
    36001 gtagaaaatg tttcaaagga taaatagtta aattagctgt ctcaatacag aattaattct
    36061 aaaggagatg gcttttttat gcgaaaatca aaaatagata catagtaagt tacctttttg
    36121 taggaatata tggtatctta aatatataat atttaaataa tgtataagct caattaaaaa
    36181 atttatagag gatggaaaat aaatgggaaa taaaaataaa aatactaaat ataaagataa
    36241 aacaagagaa aggtataata aaaaagttga gaatttaaat aaagaaaaat taaataaagt
    36301 taataagcaa tctaagaagg tagataagat tgatgatatt attaataaat ctagtattgt
    36361 attatgtgta cttctagtag tgttttcatt gctttactta tttaaactgg ttcaacttaa
    36421 tataataatg atacttttag taattacagt agctattcaa caaggattgg tgtcatttgg
    36481 tgcatttaga aataaaaatt atgtaaaagc tttattttct atatttgtaa tagtatgttt
    36541 cttaattgct tttaaatatg ttgtaaatcc tgtttaaata tatcaataaa cgttctataa
    36601 ttaatataaa tagtgaagtt acagttttaa tgctattata aattttataa tttgaaggag
    36661 tagattttat gaataggtgt aagtttgcaa aattaattat cacatcaatg attgttttat
    36721 tacttacagg atgtagttta aagaaggaag ataattataa gttagaccca gaaaatccga
    36781 catcaataca aatttggcat tattataatg gacagcagaa aatggctttt gataagcttg
    36841 ttaaggaatt taatgacact gtaggtgctg aaaaaggaat tattgttgaa gcattcagtc
    36901 aaggtaatgt agttgattta tcagagaaag ttttagattc tgcaaataaa aaagttggtt
    36961 ctgaagatgt accaaatata tttgcagcat actcagatac tgcatatgaa atggataaat
    37021 tagggttact agtagatatg gataagtaca taagtaaaga agaattaaat gaatacatag
    37081 acgaatatgt agaagaaggc agaataaatt ctaaggatga gtttaaactt ttcccaattg
    37141 caaaatcaac tgaaattttg atgttaaata aaactgattg ggataaattt gcaaaagcta
    37201 caaattcaaa tataaatgat ataaaaacaa ttgaaggatt agtagagaca tcaaaaaaat
    37261 attatgaatg gacagatagt ttaacgaaag agcctaatga tggtaaagca ttttttggaa
    37321 gagatgcttt agcaaattat attattatag gaagtaaaca actaggagta gaaatttttt
    37381 ctgttaaaga tggtaaagtt acactaaata ttgatgaaaa agttatgaaa aaactatggg
    37441 ataatttcta tgtaccatat ataaatggat attttgcttc ttatggtaag tttcgttctg
    37501 atgatgcaaa aacaggtgat atattagctc ttgtaggttc tagttcagga gcagcatact
    37561 ttccagatag agtaatgcta aatgataatg agagttataa tattgaaaca tctgtttttc
    37621 aagcaccacg ttttaaagga gaaggaaaat atgctgtaca acaaggtgca ggaatggctg
    37681 taacaaaatc tactaaagaa gaagaatatg catcagtaga atttttaaaa tggtttacag
    37741 ataaagaacc taatataaaa ttctctattg cttctggata cttaccagta aagaaaaaaa
    37801 cgaatgattt ggatgttata aaagaagtta tgaagaaaga taatttgagt ttatctgata
    37861 aagttgaagg ttcaatagcc tcatctattg aacagattaa cagttgtaat ttatatacta
    37921 ataaagcatt tgatggtgga actaaagcta gacaaatact tgaatattca atgcttgata
    37981 aagctaaaga agattcaaat aaaataaatg aattagtaaa aagtggaact tctaagaagg
    38041 atgcagtagc acaatttaat aatgataaaa attttaaaac ttggtttgaa agttttaagg
    38101 ctgagcttga aaatgctata aaaaaataga tgaattggca gttagtgtgt tgacgagcac
    38161 aaaggtatag gtggaatggg tatggaaaac aatctaagaa aaaacaattc aataatgaaa
    38221 aagatgatat ttcccctaat tattgttatg ctaattcaaa caagtttatt ttgtgccaca
    38281 attttatggg gaggaactat taagaaatta aatgataatt cgtttgacat cttaaatgaa
    38341 agagtaatta atcgtaaaaa ttatatacaa aatgaaatgt tacaaagatg gtcaaataca
    38401 agtgaaacgg aagctacaat taattcctct gtaaaaaaag tattaaatga aaaaaatgcc
    38461 ttaattgagg atgtaggcaa caatgaagaa attaacaaag atattataaa aagcatatca
    38521 aatgatttaa tatatctttt gagaaaaaat tctgttacag gagcttttat aatcctaagt
    38581 gacaaaaata ttaacgataa gtcaatagat agtaaaggtg aaataagtag gacaggattg
    38641 tatataaggg atttagaccc taagtttaat ccaaatgata attctgattt gttaattgag
    38701 agaggttcat cagatatagc aagaagtttt ggaatatcta tggacagtta ttgggaacct
    38761 aagttttcat ttaaaagtga aaatgagcaa gatggagatg atttttttta taaaccattt
    38821 agagctgcaa ttgataatcc aaatgtatca agttctaatt taggatactg gggaagtaag
    38881 tttttattga caaatgcagg tgataggctt atgacatata cagttcccct tatttatgaa
    38941 gatggaactg tatatggagt acttggaata gatttaagtg taaattattt aagagaatta
    39001 cttccatact cagagataaa tggaaataaa aagggtaatt atattttagg tgtagataga
    39061 aataatgata tggcctttga aaatgtaatt tcaaatggat actcattaaa agaaaaattt
    39121 tgggatggtt tacattctaa tttagagcag aaggaatcgt ataaaaatat atataagatt
    39181 aaaaataaag ataatgaatg tggtaatggc aacatttatg ctagtgtaca atacttggat
    39241 ttatataact ccaatactcc atttgaaaat gaacgttggg ctcttttggg tattattgaa
    39301 gaaaaaagtc ttttgtcatt ttcaaaaagg gtagagaaat tagttataat atctatagca
    39361 atttctttat taataggtct aataggtatt tacattgcat caagattatt tacaaaacca
    39421 attgttcttt tagccaacaa agttagaaac agtaatccat caaaaccagt aaatcttgat
    39481 aagataaata tatctgaaat agatgaatta tcttcagcta tagagttgct cagtgcaaat
    39541 gttgcagatt cttcgtcaaa attatcacag attattggaa tggtagatat gccaattggg
    39601 gcttttgagt tatacaaaaa cgcagagaat gttttttgta caaaagaatt ttttagcgtg
    39661 tttactactg aaatcaaatt tgaagaatat ggatatatgg aaaaaaataa gttcctgaaa
    39721 aaattaaggg gactagataa atatttgcaa gaaagttatg aaacagaaaa tacatatata
    39781 tataagtttg aatctaaaga taaaaaactt aagtggataa gaatgaatat ctttgaagat
    39841 gagctaaagg ttcttggtgt tgttgttgat gtaacaaaag aatttattga gaaaaggaag
    39901 atagaatatg aaagagattt tgatatttta acgaatcttt taaataggag agcttttcat
    39961 tcacagatac aagaaaaatt taagaataaa gatgaactta agatagcagc atttattatg
    40021 tgggatttag ataatctaaa atatattaat gatacatatg gacatgatgc tggtgatgaa
    40081 tatattaggt gtgctgcaga catacttaag aagtttatat catggaatgg tatagtatct
    40141 agactttcag gtgatgagtt ttatgtattt atatatggat atgaaagcaa agatagtata
    40201 agagatatta ttaattctgt taagaaacag atgaataata ccttattaaa acttcatgat
    40261 ggaacagaat ttaaaataag ggcatcagca ggaatttcct ggtaccctga tgattcaacc
    40321 aactatgatg aattaatgag atacgcagat tttgctatgt atcaaattaa aaatacaatc
    40381 aagggtgaag ttagtgaatt tgatattaat atatataata aggattcatt cttattgagt
    40441 aatagagaag aattaaacaa gttaattgat ggtcaattag ttgagtatgc atttcagcct
    40501 attgtagatt gtaaaggtaa agtttttgca tatgaagcac ttatgagacc taaaataaaa
    40561 acttttagtt caccaataga tgtcattaga ttagctcgtt cacagtctaa attatatcaa
    40621 attgagcgta ttacatggtt taaagcactt aaatcattta aaaaatacaa agaaaaattt
    40681 ggcgattgca aactgttctt aaattctatt cctaataata atttgtcaaa agtagatttt
    40741 gaggaaattg aagatttata tggtgaatat ttaaatagag tagtactaga aataacagag
    40801 aatgataaga ttaatgaaga ttttattgag aaaaagaaag catatataga ccattggaat
    40861 atagaaattg ctttagatga ctttgggaca ggttacaacg gagatgctgt actattatat
    40921 ataatgccag actatgtaaa gattgatatg tctattgtaa gaggtattga taaagatgaa
    40981 aacagacaga aaatattaaa aaatcttatc tcatattcta acgaaagaaa tattaaagtg
    41041 atagcagaag gtgtagaaac aaaaggtgaa atggaaacac taattaatct tggagtagat
    41101 tatatgcaag gctactatat tagtaaacca tcatttatac ctgaagatat aagcgacaaa
    41161 attaaaaaag aactcaagat atgtcatgaa aataggaatg atgtggttta atagaggaaa
    41221 aattaaattt atttttatga acttttagtt tataattaaa aagaaaataa tataattata
    41281 aatcaaggtg gtggagctaa taatcacaac aaatatagat ataagaaagt taaatgaaaa
    41341 tcaattagaa gcagttgagc atatagatgg gccttgcatg atacttgcag ggcctggttc
    41401 aggtaagacc agagtaatta catatagaat agccaatatg gttgtaaaca aaaacatagc
    41461 accaacaaga atcttggcaa taagttttac caaggcatct tcaatagaaa tgaaaaatag
    41521 agctttgaat ttaagtgatg acataagact taataaggta acctatggta cttttcactc
    41581 tgtatttttt aaaattctaa gatactttga aagatacaac ttagacagta tatttgatga
    41641 aaagtcaaag cgaatgacaa tcaaggcaat cctaaaaagt ttaaatatag agaatgctga
    41701 tgatgatgag aatataggac aagttataaa tgaaatttcc tatgtaaaaa atgaacttat
    41761 ggataaaaat gaatttaatt cagaagtatt aacaaaagat gagtttttaa aagtatacaa
    41821 cttatacgaa gaacaaaaat ctaaagttaa taaaatagat tttgatgata tgcttataag
    41881 aacttattat ttacttttga acaataagtc tgcactagaa atggttagaa atgtgtataa
    41941 atatatattg atagatgaat ttcaagatat aaataaagta cagtttgaag ttttaaagtt
    42001 aatttgtagc ccattaaaca atatatttgc agttggagat gaagaccaaa gtatatatgg
    42061 atttagaggt gctagaccag attttttgct tgaatttgaa caatacttta ataatactaa
    42121 aaaaataata ttagatataa attacaggtc taaaagtgag atagttcata ctgcaaatag
    42181 acttattgac aaaaataaaa atagatatga aaaaatcatt aagtgtagtc agggggatgg
    42241 aggaagtgtt acctatattt ctccgcatga ttcagaggaa gaagccttat atattgccag
    42301 ggaaataatt gacgaaatac aaaaagatta tgtagagtat tcagattttg cagtaattta
    42361 tagaactaat atacagtcaa gagcattagt agatgtattt atggatatga ggattccatt
    42421 tgtagtaaaa gactcagtaa ttacaatata tgaccattgg gcaagtcaag atatactagc
    42481 ctatttaaga ataggtatta atccaaaatc aaataaagat tggttgagaa ttataaacaa
    42541 gccttttaga tatatatcca aagacagtat aaatatggtt aaggatgaaa aagactttat
    42601 aacagcatta ataaataagt gtaatcttca tcctaaacaa gttaaaacaa taaatgattt
    42661 ggaaatagat ttaagttatt taaatacttt aaatcctaaa aatgcaatat cttatattag
    42721 aactagtctt gattatgata gatatgtttt agattattgt agcaacagaa agataaagac
    42781 taatggactt gtagagatat taaatgaact tgagagttca gcaactaatt ttaatactgt
    42841 tacagagttt ttagagcata ttgatagagt aaagactgag ttaacggaaa ataacaagaa
    42901 taagcagact gagggtgtca tatttacaac tatgcatagt gcaaaaggat tagagtttag
    42961 aaatgtttat attataggtg taaatgaagg aacaatacct catgaaaaat catatgatat
    43021 ttgtaaggaa gagaaaaaag aagaacaatt agaagaagaa agaagactta tgtatgttgc
    43081 tattacaaga gctgaagaaa agttatgtat aagctctact ttaaataagt atggtaagaa
    43141 agttgataaa tcattattta ttaatgatat aaaatctcca acgaaaaaag aaattgacag
    43201 tattggtgta ggggataagg tataccataa aaaatttcat gaaggagaaa taattaaaaa
    43261 agatggaatt atgtttacaa taaagtttaa agatagagag cgaatcttgg atttgaaaac
    43321 ttgtttattg aagaatataa tttatactat ttaatttaga atctaaattt agatataaat
    43381 ataatgtatt atttattatg tgcaagacaa atagatatgt gtaaaatgta ttatttaact
    43441 tattagaaaa agaaataagg gtttaatata ttatttatag ttgtttagaa aaagcaacaa
    43501 tgtggaaaat attatttagt attattaaag aaaagcaaca atgtgaaaga tattatttag
    43561 tattgtttaa gaaaaagcaa caatgtgaaa gatattattt agtattattt aagaaatagc
    43621 taaaaatatg aaatatacta tttataatta cacaaataat atcaataaat ataaacagta
    43681 gtatttagat aatttacaag taaaaattat taaaaaaata aaaaacttat tgacaaaaat
    43741 attataagga agtacaattg tattaacaat ttaaggaaac aaatccaatg atagagaaag
    43801 tagcatatat ggatttacag cgagttaggg gttggtgtaa gcctagcaat gaagtctatg
    43861 tgaagagagc tctggaggag attatcagaa actttagtat gataattggt ttacccgcct
    43921 taagggattg agaggataag tacttactta tcaaaaagag tggtaacgcg gatataattc
    43981 gtctcttagc tgtaaagcta agggactttt ttgattttaa aataaaaata tccatacagc
    44041 ttaaaagcta acagtcacaa attttgaaag taatataagt atttatcaat aagagtggta
    44101 acgcggtaaa gtcgtctctt agtcattaaa gactgagaga ctttttttgt aactcgaaac
    44161 atttaagtat taaaatctga gggaaattat aattaaaaga gaggggtagt taaaatgaaa
    44221 gtatttaaaa aattattaag tttaggatta gtattaggat tgacattatc gctagtagga
    44281 tgtagtggtg gaggagaaaa aacaaagtta gaacaaataa aagacaatgg aaaattagtt
    44341 gttggtacta gtgcagaatt tcctccattt gaatttcata aggtagtaga tggaaaagat
    44401 tcaataaaag gattcgatat aatgttggct gaagaatttg caaaagagct tggtgtaaag
    44461 gttgaaatta aggatatgtc atttgatgga ttaataggtg ctttaaatgc agaccaagtt
    44521 gatattgttc ttgcaggtat gtctccaaca ccagagagag aaaagagtgt tgatttctca
    44581 gaattatatt atttaagtag aaatgcagtt atagttaaag atgcagatat agacaaagta
    44641 aaaactgaag atgatttaaa gaaacttaga gttggagttc aagcaggaag tatccaagaa
    44701 gaatatgtag ttaacacttt aaaaatgaca actacaaaat ctttgaaagc aatacctgat
    44761 ttaattacag aattaaaaaa tggaaacata gatgcagttg ttactaatga agcagtttct
    44821 ttaataaatg ttaaaaaata tgatggaata aaaatggcaa atactgaagt tgggaaagat
    44881 gtaacagaag gtatggcagc agcaatcaaa aaatctgaca ataacaaaga ttttatagaa
    44941 ttattaaaca aaaagataaa agaattacaa gatggcaaga agatagaaga atttttaaat
    45001 gaagcatcta ctgaagctgc ttcaaattag taagaaagtt atgtgggaga tgaaattatg
    45061 agtttagatt ttagtttttt aagtagattt gggacttctt ttttggaagg aacaggtgtg
    45121 acagtatcaa tttctcttgt ggcattatgc tttggattta taataggtat aattatctgt
    45181 atggcaaaaa tatcaaagag caaagtatta agagcaatat catcaatcta tattgaggtt
    45241 ttaagaggga caccattatt agtacagata tatatagtat ggtttggttt acctcaatta
    45301 ggaataagat tccctatgtt gtttggtata ccaagtgaat ttatagctag tgcatttgca
    45361 ttatcagtaa actctggtgc atacgtggca gagatactta gatcaggtat acaatcagtt
    45421 gataatggac aaatggaagc aagtagatca ttaggattaa attattggtc aactatgaga
    45481 tatataataa tacctcaagc tataaaaaat atattacctt cattagcaaa tgagtttatt
    45541 acacttgtaa aagaatcttc aataatatct gtaataggag ttgttgagat aatgcgtact
    45601 gctgatatag taaaaaatgc agcatttaga gcattagagc cattaatagt agcagcagca
    45661 atttactttg ttataacatt tactctatca agattagttg gattattaga aaagaaacta
    45721 tctgtgtcta actagatgag agcatgttta gcatttaggg aaaacataga atagtaaaaa
    45781 ggaaagtgat aatatgatta caataaaaaa tttaagtaaa tcttttggag atttaaatgt
    45841 attaaaaaat atagacttag aaatcgctaa aggcgaaata atggttatag taggtccaag
    45901 tggttctggt aaaagtacac ttcttagatg tatgaattta ctagaaatac ctacaggtgg
    45961 agaaataata tttgaaggaa aaaatttggt cgataaaaaa actaatattg atgaggttag
    46021 acaaaatata ggtatggtgt ttcagaactt taatttattc ccacataaga ctattttaga
    46081 taatataaca ttagcaccaa ttaaattaaa aaagatgact aaggaagaag cagaaaaaaa
    46141 agcagaaatt ttgttgagta gagttggtct tttagataaa aaagattcat atccatcaca
    46201 attatctgga ggacaaaagc aaagaatagc aatagctaga gcacttgcta tggaaccaga
    46261 tatgatgttg tttgatgagc caacatctgc tcttgaccca gaaatggtaa acgaagtttt
    46321 ggatgttata aaagaacttg ctaaagaagg tatgacaatg gcaattgtaa ctcatgagat
    46381 gggatttgct aaggaagttg cagatagagt tatttttata gatggaggaa gtatacttga
    46441 agataatact ccagaagaag ttttcggaaa tccaaaacat gaaagaacaa aagcattttt
    46501 agcaaaagtg ctataatata taaaaaggat gttattgata ttagaaattc aatacatcct
    46561 tttttagtga tggttaatat taattttaaa attaaagtta tattaatatt aactttattt
    46621 ttacgatttt ttgcagaaaa aaaaagagct cggggtaagc tctttttttc caccgaatta
    46681 atttccgtta ctaatccgat ttttaataaa tataaaatat atccttatga aagggtattg
    46741 ggaatagata tattaactaa ctagggttac cagggggata accttaattt attataacaa
    46801 aatgcgacac aaaaatcaat attttttttg aaataaatta taaaagttat ttttataaca
    46861 agtaagctta taaatttaac ttttatagta a
//
LOCUS       DAEPXW010000022        46504 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.022, whole genome shotgun sequence.
ACCESSION   DAEPXW010000022 DAEPXW010000000
VERSION     DAEPXW010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.022"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            58..819
                     /locus_tag="KRM55_001194"
     CDS             58..819
                     /locus_tag="KRM55_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1593444.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(1079..3007)
                     /locus_tag="KRM55_001195"
     CDS             complement(1079..3007)
                     /locus_tag="KRM55_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1593445.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVYNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            3241..3693
                     /locus_tag="KRM55_001196"
     CDS             3241..3693
                     /locus_tag="KRM55_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1593446.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            3696..4004
                     /locus_tag="KRM55_001197"
     CDS             3696..4004
                     /locus_tag="KRM55_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH1593447.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            4118..5224
                     /locus_tag="KRM55_001198"
     CDS             4118..5224
                     /locus_tag="KRM55_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH1593448.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            5299..7977
                     /gene="mngB"
                     /locus_tag="KRM55_001199"
     CDS             5299..7977
                     /gene="mngB"
                     /locus_tag="KRM55_001199"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH1593449.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDKYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGINSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDLYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(8294..10627)
                     /locus_tag="KRM55_001200"
     CDS             complement(8294..10627)
                     /locus_tag="KRM55_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1593450.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGGA
                     KNPFEQESFVGSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITGIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAEMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(10602..11318)
                     /locus_tag="KRM55_001201"
     CDS             complement(10602..11318)
                     /locus_tag="KRM55_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593451.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            complement(11732..12388)
                     /locus_tag="KRM55_001202"
     CDS             complement(11732..12388)
                     /locus_tag="KRM55_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1593452.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(12443..13072)
                     /locus_tag="KRM55_001203"
     CDS             complement(12443..13072)
                     /locus_tag="KRM55_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1593453.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(13203..13844)
                     /locus_tag="KRM55_001204"
     CDS             complement(13203..13844)
                     /locus_tag="KRM55_001204"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBH1593454.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(13853..14524)
                     /locus_tag="KRM55_001205"
     CDS             complement(13853..14524)
                     /locus_tag="KRM55_001205"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH1593455.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(14529..15413)
                     /gene="rsgA"
                     /locus_tag="KRM55_001206"
     CDS             complement(14529..15413)
                     /gene="rsgA"
                     /locus_tag="KRM55_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH1593456.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDENEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(15511..16248)
                     /locus_tag="KRM55_001207"
     CDS             complement(15511..16248)
                     /locus_tag="KRM55_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH1593457.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(16356..18371)
                     /gene="pknB"
                     /locus_tag="KRM55_001208"
     CDS             complement(16356..18371)
                     /gene="pknB"
                     /locus_tag="KRM55_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBH1593458.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(18388..19140)
                     /locus_tag="KRM55_001209"
     CDS             complement(18388..19140)
                     /locus_tag="KRM55_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBH1593459.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(19160..20191)
                     /gene="rlmN"
                     /locus_tag="KRM55_001210"
     CDS             complement(19160..20191)
                     /gene="rlmN"
                     /locus_tag="KRM55_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBH1593460.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(20199..21524)
                     /gene="rsmB"
                     /locus_tag="KRM55_001211"
     CDS             complement(20199..21524)
                     /gene="rsmB"
                     /locus_tag="KRM55_001211"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBH1593461.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(21586..22287)
                     /locus_tag="KRM55_001212"
     CDS             complement(21586..22287)
                     /locus_tag="KRM55_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBH1593462.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(22356..23108)
                     /locus_tag="KRM55_001213"
     CDS             complement(22356..23108)
                     /locus_tag="KRM55_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBH1593463.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(23118..24047)
                     /locus_tag="KRM55_001214"
     CDS             complement(23118..24047)
                     /locus_tag="KRM55_001214"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBH1593464.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKKFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(24062..24502)
                     /gene="def"
                     /locus_tag="KRM55_001215"
     CDS             complement(24062..24502)
                     /gene="def"
                     /locus_tag="KRM55_001215"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH1593465.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(24520..27045)
                     /gene="priA"
                     /locus_tag="KRM55_001216"
     CDS             complement(24520..27045)
                     /gene="priA"
                     /locus_tag="KRM55_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBH1593466.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYRKPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(27284..28483)
                     /gene="coaBC"
                     /locus_tag="KRM55_001217"
     CDS             complement(27284..28483)
                     /gene="coaBC"
                     /locus_tag="KRM55_001217"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBH1593467.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(28488..28754)
                     /locus_tag="KRM55_001218"
     CDS             complement(28488..28754)
                     /locus_tag="KRM55_001218"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBH1593468.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(28757..29374)
                     /gene="gmk"
                     /locus_tag="KRM55_001219"
     CDS             complement(28757..29374)
                     /gene="gmk"
                     /locus_tag="KRM55_001219"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBH1593469.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLKELKNRIVGRGTETETEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(29404..30285)
                     /locus_tag="KRM55_001220"
     CDS             complement(29404..30285)
                     /locus_tag="KRM55_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBH1593470.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRIPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(30289..31119)
                     /locus_tag="KRM55_001221"
     CDS             complement(30289..31119)
                     /locus_tag="KRM55_001221"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBH1593471.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDREIKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(31406..32440)
                     /gene="ltaE"
                     /locus_tag="KRM55_001222"
     CDS             complement(31406..32440)
                     /gene="ltaE"
                     /locus_tag="KRM55_001222"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBH1593472.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            32736..34511
                     /locus_tag="KRM55_001223"
     CDS             32736..34511
                     /locus_tag="KRM55_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBH1593473.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSRFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(34726..36378)
                     /locus_tag="KRM55_001224"
     CDS             complement(34726..36378)
                     /locus_tag="KRM55_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1593474.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKAPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     MQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(36677..37888)
                     /locus_tag="KRM55_001225"
     CDS             complement(36677..37888)
                     /locus_tag="KRM55_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBH1593475.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(38172..38705)
                     /gene="pyrR"
                     /locus_tag="KRM55_001226"
     CDS             complement(38172..38705)
                     /gene="pyrR"
                     /locus_tag="KRM55_001226"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBH1593476.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(39065..40012)
                     /locus_tag="KRM55_001227"
     CDS             complement(39065..40012)
                     /locus_tag="KRM55_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH1593477.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(39981..40427)
                     /gene="lspA"
                     /locus_tag="KRM55_001228"
     CDS             complement(39981..40427)
                     /gene="lspA"
                     /locus_tag="KRM55_001228"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBH1593478.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(40737..41516)
                     /locus_tag="KRM55_001229"
     CDS             complement(40737..41516)
                     /locus_tag="KRM55_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1593479.1"
                     /translation="MKKIIWGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(41571..42053)
                     /locus_tag="KRM55_001230"
     CDS             complement(41571..42053)
                     /locus_tag="KRM55_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH1593480.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(42319..43740)
                     /locus_tag="KRM55_001231"
     CDS             complement(42319..43740)
                     /locus_tag="KRM55_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH1593481.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGINDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(43886..44656)
                     /locus_tag="KRM55_001232"
     CDS             complement(43886..44656)
                     /locus_tag="KRM55_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593482.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELSNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(44661..45863)
                     /locus_tag="KRM55_001233"
     CDS             complement(44661..45863)
                     /locus_tag="KRM55_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1593483.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT        15509 a         7974 c         5009 g        18012 t
ORIGIN      
        1 tgtattgaca tttacgttgc gtaaaagtgt atatttaatt tataggaggt actacttatg
       61 gaatatacag ttcaaaaatt aagtaaacta gctggtataa gtactaggac acttagatat
      121 tatgatgaaa taggtcttct taagccactt aaaataaatt cttcaggtta tcgtatatat
      181 ggtcaaaatg aagttaataa acttcaacaa atactttttt atagagaatt aggaattaac
      241 ttagaaaata taaaaaacat tataaattca ccaaacttcg atagtttaag tgcgttaaaa
      301 gaacaccata ataaattact agccaaaaga aagcaaattg atttactaat agaaaatgta
      361 actaaaacta tagctctgaa ggagggaaaa tacactatga cagatataga aaaatttgaa
      421 ggttttaaag aaaagatgat tgatgaaaat gaaaaaaatt atggaactga aattagagag
      481 aaatatggta aagatattat agatacatca aataaaaaac ttaaaaatat gtctaagcaa
      541 gattatgaaa attggcaaaa cctaaatatc gaaataatta gtaaacttaa aaaagctttt
      601 aaaactggtg atgcctctag tgaactggct caggaagttg caaaattaca tcataaatgg
      661 ttgagttaca cttggaacac atactctaaa gaagctcatt cctctctagc acagatgtat
      721 gtatatgatg aacgttttac atcatattat gatagagaac aacctggatt agctaagttt
      781 ttaagggatg ctatagtaat atatacaaga gataaataat ataaaataat aaaggtggtg
      841 tctcaaaatg aactttttag ttcatgagac actctttttt gtatgaaatc aaatatattt
      901 ttatcatttt atcaatgaaa aacaggtttc tctctctatt ttgagacaga atctttattg
      961 tataataatt ataatcaata caaaataata acaaattata taaaacttac ttatactatt
     1021 tatgctaaaa acaaaaaata ttttattaaa gtttttaaaa cttatgtaat ataaaaatct
     1081 atactataga cttgattatg gaaagaaaat tatcaaaatc attacaatta gatatactat
     1141 ctctaatatc attgtcatga attatcttta aaaggatatc ataaatggag tttattttta
     1201 tataatcatc tttatttata gccaacatca tgattaattt aacagtagaa tcttcactcc
     1261 aatatattgg ttcattcaat atggaaatac aaatcttagt tcttatagag cttaattcca
     1321 taggatgagg tatagctaaa aaatcatcta tattggtaga agataaactt tctctgtaaa
     1381 atacagattc agcaaatgat ggaaatacaa tttcactttg agttaatttg ttgcacatca
     1441 actttataag ctcatcttta tctttgattt taggattaac aataaataaa tttttatcaa
     1501 agaaattgtc caaaagatta ctataaatat gggaattatt agtgattgac ttagatatat
     1561 tctctatatc tttttttaat agttttaaat ccactaatac aataggaata ctatcatgat
     1621 ttaaaggaat tgtcgatatt attatatcta catctgacaa ttcactagct aaaaattgat
     1681 taaatgatag acattgaagt atatttattt tatcatgaaa aactttgttt aattgaacct
     1741 ctaataacct acttgaacca taccctgaac cacatactaa tactacgttt ttacacttaa
     1801 tattactttg aaaaaatctc tctattccag cacctatatg cagggataca tatccaattt
     1861 catcttctgt taaagagtaa atactatttt taaaaacttt ttctatagca tttaaagtta
     1921 tttcaaatgc taaaggataa ttactcttta ttgtatttat aaggggattc accttattta
     1981 aattataaga tttagaattg agaattgatt taaagtgcag tactaaatca tcaaataata
     2041 cactatcatt tctaaggtca aaagtatatt gattgttgat tacttctaaa atttcttcaa
     2101 catactctat aattttagta tctaccctat tgtaaacgtt atccaaaaga gaacttttag
     2161 ttataaaatg attatataga taaactctgt ctgcctttga aataattata gtatatttac
     2221 tctcaatata attaaatata ttttcaacag ttgtattcga ttgaaaatct gttaaaacaa
     2281 catctaaaac attatctaag cagtaaccat caagtattct acttacagta atagctaaat
     2341 ggataataaa gttttttaga ttaaaatcta ggaaattgat attaaattta ttaatttcac
     2401 ttaacactac cctttgaagc tctattaaat ctacattatt aaataattct atttctctat
     2461 ctgtaattcc aattatatag ttttcaaaat tcctatttat catattatta gaaatacatc
     2521 ttcgaatatc tatttcctta ccttcaactt taactccata atatggctta gaaactaata
     2581 ttaaattata ctttgacaaa ataggcttta ttctttttat gtcatttagt attgtaaatt
     2641 tactcacata caagctatta gctaaatctt ctagttttat atatgtattg ttatagagaa
     2701 tatattttaa aatatattga tttctttcta taggagaatc tggtatttca cttgaatcca
     2761 taatatcatc agatattaat gctagatact gttggtataa tgctaaatta agaatatcta
     2821 tataatatcc ttctcctttt tttattttaa taatagcacc atttttctct aaagttccat
     2881 ttatagaagt aatatcattt cttatagttc tctcactcac ttttaaatga ttacttaaag
     2941 ttttacaagt aattttatca tcactttcat ttaataattt aaacaacgtg agcaatctct
     3001 tgtgcataaa tatcccccct tatagaattt cttctaaatt atactattta cactcatata
     3061 atacaattac tctaataaaa ttgtattata ataatttatt tccacttcta tatggaaatt
     3121 agttattatc ataatataaa tttccatgtc gaagtggaaa ttagttatat ttaatttaat
     3181 taggataatg attacaatat aaatataagt taagacatta tgaatggagt ggaaaaatat
     3241 atggtactac aagaaaaata tatatttata gataaagact taaaaagcaa agaagaagta
     3301 ttaaatttta ttgcagatag tgcttatata ctaggtatta caactaataa agaggctctt
     3361 ttaaaagacc ttctaaaaag agaaaatgaa tttccaacag gaataaaaga tggatttgcg
     3421 atacctcata caaaaagtgt aaatgtaaag gaagcttcca tactctatat taaaacaact
     3481 aacgagttag agtggaaaac tttagatgat agtaaggtta gatatgtatt tagtttgtta
     3541 gccccacata aaaatgaagg aaatatacat ttgaaaactc tatctaaatt agccacatgt
     3601 ttaatggagg atgattttac aagtgaagtt aaaaatgcta gtgatgcaag tcatttagta
     3661 aaatatataa ctaataaaat gaaggaggaa taattatgaa aatagtagca ataacatcat
     3721 gtatagcagg attagcacac acacctatgg cagcaaaagc tttagaacaa gctgcatcaa
     3781 aaatgggtca tgaaatcaaa gtagaacaac aaggtgctat gggacgagta aatactataa
     3841 caaaagaaga agcacaagat gcggacttta tacttatagc atctgaccaa actatatctg
     3901 gaatggaaag atttgatggt aaaaaagtga taaaagtcaa aataggtata gcgttaaaaa
     3961 aaccagaagc tgtcttaaca aagtgtatag aagctatttc ttaataaaaa aatctcactc
     4021 taatatagaa tgagaaaaat caaaaattaa aaaattgtct aatataatta taacatatta
     4081 tcaaaaaata taacaaactt atataggagg attaaaaatg agtaaaaaaa ataaatctct
     4141 tttaagtgaa cttaagggac acttaatgac aggtatctca tatatgttgc cacttgtaat
     4201 aggctcatct ttagttgtag ctatcccaaa gcttacagct ttagcaatgg gtataacaag
     4261 tttagatgct tataaaaatg tatctggttt ttatcatatt ctttacttaa tggaacaagt
     4321 tggttggact ggcataggtc tattaaatac ggtattagca ggatttatag cattttcaat
     4381 aggtgagaaa ccagctatgg gtgcaggttt tattggtggg ctcatagcaa gtaatactaa
     4441 tgcaggattc ttaggagcag taatagcagg tttctttgct gggtatgttt gtaagttttt
     4501 aaagaaaaaa attaaaatat ctgggtcagc atcaggaatg atgccactta taataatgcc
     4561 acttataaca gttggattaa ctggtttttt aatgagtgtt gtattagcag gacctttagg
     4621 aaacataaat acttcattaa atgcttgggt agctgaaatg tgtcaaaatg gaacaaattc
     4681 ggtggtattg gctttaattt taggcgcaat gataggattc gatttaggtg gaccagtaaa
     4741 taaagcagct tggatggcag gaaatgcatt attgttagag ggaatctatc taccagcgat
     4801 attggtaaac tgcgcaatag ttatacctcc actaggatat ggtttagcta cattcataag
     4861 aaaatcaaaa ttttccaatg cattagctga aacaggaaaa ggcaatatag ttatgggtat
     4921 aattggaata acagaaggtg caattccttt cactttaaca aatccattaa aattagttcc
     4981 tgttaatatg ataggatgcg ctttgggtgt aggattatca gctttgttag gtgtacatgc
     5041 tataatgcct ccagttggtg gattatatgg atttatatca ataggttctg gatgggctta
     5101 cttagtaggt gcaatatttg gagctttagt aatagcaata ttatcaacaa ctttagtaga
     5161 cttcaatgaa gatgaaacta cggaaaatac agaatttgat gaaatagagt tagatataat
     5221 gtaaattaaa aacttaattt tagataattg agaattgagt gtactctcaa ttctcaatta
     5281 aattttggga ggatttttat gaaaaagaca aaagtacatg tagttccaca cagtcattgg
     5341 gatagagaat ggtattttac aacatcaagg tcaaaaatat atttaatgaa agattttcaa
     5401 gatatattag acatattgga agaaaaagaa gactttaaat actttactat ggatgcacaa
     5461 gcttctctct tagatgatta tttaaaatgg agacctcagg ataaatatag aataagagat
     5521 ttagttcaaa gaagaagatt agttattgga ccttggtata ctcaaacaga ccaattggtt
     5581 atatcaggag aatctataat tagaaacctt tactatggaa tagatagatg caatgaattt
     5641 ggtgaaccta tgagggttgg atatgtacca gattcttttg ggcaatcagc tcaaatgcca
     5701 caaatataca gaggttttgg aataaatagt tcattatttt ggcgtggagt ttctgatgat
     5761 atggtagata caacagagtt tatatggaaa ggttctgatg gttcaaaagt attagcagtt
     5821 caaataccat ttggttatta ctatggaggt aatataccag aagatgattc tgatttaaaa
     5881 gaatatttaa aagatataat tggaaaactt aaggttaaag cttctactaa taacgtatat
     5941 tttccaaatg gatttgacca agcaccaata agaaaaaacc ttcctgatat attaaaaaaa
     6001 gctaatgaaa tagataatga aaatgaatac gaaataagtg atatagaaaa ctatatagat
     6061 tcagtaagaa atgaaagaaa tgaatttaca gagcttaaag gtgaattttt aaatgctaaa
     6121 catatgagaa tacacaaatc catattctcc tcaaggtcag accttaaaat aatgaataac
     6181 aaattagaaa attatattac aaatgtactt gaaccattat taacattaag ttattcactt
     6241 ggaaatgaat accctcacct agttataaaa gatatatgga aacttatgtt tgaaaatgca
     6301 gctcatgaca gcataggttc ttgtaatagt gacacaacaa atgaggatgt atacacaaga
     6361 tacaaacaag ccagagattt gagtataaat ttattagatt tgcatatgag acttataagt
     6421 actcaaatca aaaataataa tgaagaaata acattaacag tattcaatgg attcccagaa
     6481 gtcagaaatg aagttgtaga atttgatact tatattccag gtcaagattt tgtgataaag
     6541 aataaaaatg gaaaaattct taattatata ataaaagaaa aagaagatat tacaaattat
     6601 atattaactc aaacaataag attaaaccca agtaaaaaaa tatatatacc caaaactgta
     6661 tatagagcaa aaattgcact ttcagtaaaa gatataccac caatgggata tactcaacta
     6721 gtttttgaat tggatactaa aaataaatgt gaaatagaaa caagtaattg caaggaaata
     6781 gaaaacaaat actacaaaat aacagccaat aaaaatggtt cattagaaat attagataaa
     6841 gaatctaata agacttataa aaaccaagct gtaattgaag acaatggaga tgatggagat
     6901 tcatacaact attctcctcc aagaaaagat ctttatgttt catctttaga ttctgtatct
     6961 tcagtagaag tgctaaaatc aaacattcaa gaagaaatga tacttaaata ttcattgacc
     7021 ataccaactt cactggaaga aagggctata ggtaaagttt ctgtgaaaat gccagtaaca
     7081 atgaaaatca ccttagaacc taaagaacaa ataattaagt ttaatgttaa tataaaaaat
     7141 aaccaagcac tatctcatag agtaagagtt ttatttaata cagaaatagc atctaagttt
     7201 tctatagcag atcaacaatt tggaataata caaagaccaa cagtattaga aaaagacctt
     7261 gcattgtgga aaagagacaa ttactcatgg caagaaaaac ctataactat cgaaccaatg
     7321 caaagttttg ttactttaga ggatggacaa agaggaatag cattaataac tggttgtgta
     7381 agagaatatc aaatagttgg tgataattta gatacaatag cattaacact attcaggtca
     7441 tttggatata tgggaagaga aaatttactt tatagaccag gaagagcttc tggagaaaaa
     7501 ataatagcaa caccagatgc acaattactt aaagagttaa actttgactt tggtctttac
     7561 atatataaca ataaatttga tgaagcaaat gtagctaata cagctaagag attcttaaca
     7621 cctatacaaa tatatgaata tgctgatttt ttaaatggta gacttatatt tgcattcaat
     7681 gacgaaaaac aaatatatga aaatgaattt agtttgatga atgtaaataa ttcaaatttc
     7741 acagtaagtg caataaagaa agaagaaaaa ggagatggaa ttgtagttag aatcttcaat
     7801 ggtatgaaaa atgaggatgc taagggaagt cttaacatca ataaaaatgt caatgatgct
     7861 tatagtgcaa tgctcgacga aatctatgat aatactagca agcttaaagt aaatactaaa
     7921 actgtagagg taaattcttt atcacattgt aaagtacaaa caatagtaat taaataatat
     7981 aaaatagctt atacaagatt tcaaaataaa ttgctagtac tatgttaata gtaaagccag
     8041 atattatgct atttataagc tctgtaacac taaataacat tttgtaaaat aaaaaggtga
     8101 accttgtata ttaggattca ccttttttaa ataaatcaac attctgtttt aaaataacat
     8161 ttataagctg ttttgaaata atgcttacaa attattttaa aacaatacct ataaattttt
     8221 atttaaagaa tacacataaa tatttccaga ttcttttatt ctatagactt tataattatt
     8281 aaagaagtct aatctaattt ttgttaaaag taattgtaac tttgaataaa tcaccatcca
     8341 cacttatatt catcttacca ccctgtaatt ctataaaact ttttgctatc gctaaaccaa
     8401 gaccagaacc ttctgtgtta cgtgatttat ctcctcttac aaatctctcc attatatcat
     8461 ctacactaaa atcaatctca gatgcagaca tatttttaag cataatattt actttattat
     8521 ctgtttctaa aatatcaata tacactcttg aatttggcat tgcatatttg cttatattta
     8581 ttataagatt ttcaaatact ctaaatgtac gctgactatc taatggtaat attatttttt
     8641 cattagaaaa gttattcttt actattagag atgaatctgc aagtttgtca tctaattcta
     8701 aaagtgtctg cttcattaga gatacaatat ccacatttac tatattcaaa taaacatctc
     8761 cactatttgc cttgcttact tcaaacaaat cttctattag atgttgcaat ctttgtgact
     8821 ttctgtctaa tgtatcaata tacaacttac gattttcatc tgttatactt tcatctttta
     8881 ataaatctat ataagtgatt atagatgtta gaggtgtttt taagtcatgt gatacatttg
     8941 atataagctc tgttttcatc ttttgactct taacctcttc gtcaacagct tttttaaatc
     9001 cagtttgaat atttcctaat tcgtctttta taggattaaa aaatcctaaa tctttttcca
     9061 tatttacatc taagtttcca tctgaaattt tctttgtaac atctaaaagt tgattatatt
     9121 catatattgt ctttttagag taatctgaca gtatcttaaa taatactact gaatatatta
     9181 atgcgagtat tattccaaag aaccacatac tacacattat aactataatc aataaattta
     9241 ttcccaaaat tgtaactata gttttatttg gcttttcttt tagatttatt gttctaattt
     9301 gattaataac tgtttttcct gcttttttta gccatacaaa aaacattcct gtcacagtat
     9361 gttttgtaaa atactctctt attccaacat ttaaaatatg ttttaaaagt attataaata
     9421 caaatattat tgagaatatt acaaaccaat aagttaaatt cattaaactt accaatatac
     9481 tagccatttc agcacttatg tcattgttta taaggtactc tacataattc ccactcaagg
     9541 tattacttat tataacagta ggatataaat ctacaagccc ctgtataata gcaagagcaa
     9601 taaagagtat ctctaacggt attcttgata atgtatcaaa tcctagcaac tctttagatt
     9661 ttctatatgg gaatgctaaa gctacaataa caactatagc taatataatt tttaaaatca
     9721 ttccagaaat cttataataa gaattatttt ctacattgct tatatatgaa attataccat
     9781 catcaaaata agtatttcca taaccatact ctacactatc acctttactt attactttag
     9841 gtacagcata tactaatgtt atatttttta ttggagataa cttatatgaa attgaatttc
     9901 ctcctaaact tgtatccatt aaatcttctc ttgctttaga taacaacatt tgattaataa
     9961 ctttttgatt tactccataa gaatccacaa tatttacttt tccatcttta tcaaaattca
    10021 ttacaacgta gaatctatag ttttctttta tacctgtaat ctgcttttgt ctttcctcat
    10081 cattcatttc tgtatttttt gactgatttt catcagaatt ttcttttgaa gcatcattct
    10141 ttgttgtatc aagtactcct aattctttat tatcattaaa aaattcaaaa ttgctttctt
    10201 tatcaactaa atagtacttt aaattctttc ctgacgcttt aatgaaatgc tcccaatttt
    10261 caaagttttc attaaaatct gcattaatac tatcatctgt atagtaagtt tctgaaccat
    10321 cataagtatc tttttcttta cttacatttt ttatatagtt catagtttct tcattgataa
    10381 atagctttga tggttgtatc atcttacctt cttgttcttc cttcatatta tgatataaaa
    10441 cataacttcc tttatatata ctacctacaa agctttcctg ttcaaatgga ttctttgctc
    10501 cacctttagc acctgcttgt atagtagaat attgactaat catacctaat gatgctgata
    10561 acataagtat aaaaactata atagtaacta tatatttatc tttaaatttt ttcaattttg
    10621 tatccaacac cccacaccac ctttaaatat ttaggatttt ttgggtcaat ctctatcttt
    10681 tcccttatat tcctcacatg taccataact gtatctgtat ttacagcatt ctcattccaa
    10741 actctttcat atatttcatc agcagaaaaa actcttcctg catttctcat aagtaaactt
    10801 agtattttaa attctatagg agttgttttt atatactttc catcaatact aacttctttt
    10861 gtattttcat ttaattctaa tccgcctatt gcaaacacac tatcgtcact ttctaccttt
    10921 tgctctttat ttccaaccat gtttagatac ttagtgtacc ttctaagttg tgaattaact
    10981 ctagccaata gttctaatgg cttaaaaggt tttgttacat aatcgtctgc tcctatatta
    11041 agccccatta ttttgtcaac ttcctctgat tttgcagata gcattattac tggaaaatta
    11101 tagttttctc taagcttcat tgtaagtgtt ataccatcca ttttaggcat cattatatca
    11161 actatagcta aatgtatttc ttggttttct ataaccttaa gaccttctaa tccattgtat
    11221 cccttaaaaa cattatatcc ttgatttaat agatatattt ctatagcatc tgctatctcc
    11281 ttttcatctt ctaccaccaa aatattatat gaattcattc taatctcctt tatattaatt
    11341 tataaatttt ctttacatat atgattatac aatatgatag aagtttttcc atttatatat
    11401 atatttatat cttttgttct ggttatttgt atttaatgtc catcttagaa acctccttct
    11461 agtttaaatt taatattttt tcattttgtt ttatatactt aatattaaac ttaaaaactt
    11521 aagatattac atatactttt ctaaagattt tctaaagatt taaatatatt taaaattaat
    11581 atacaaaaaa agtagttctt attgtattaa ttaaatcaat gatttgaaat ataaaattaa
    11641 tatcaataaa acctactttt taatttttta aatatttatt tttaatttat tttgttttta
    11701 atttacttcg attttaaaat gtccttgact tttattttat aaatgtacat atttcttcta
    11761 ctggtttttt agatggactc ttcaaattgt cctctggcac tccaagagct aacattgcac
    11821 ctaaaaaata ctctcccttt tcaaaaccag tttctgcttc taaaacagct tctatctcat
    11881 ctgctgcata gttttgactt gtcaaccaac aagaaccata tccaagttca attgctgata
    11941 gtgtaaagtt ttcaattgca gcacctagac tctgcatacc tggatttctt ataaataatt
    12001 tatctatagt ctccttaggt gcatctataa gctctaattc ataatatcct gatggattat
    12061 atacctttgt aaaaactaat actaaaactg gagcttttaa gtaaaatagt gtaaaatttt
    12121 taacaaattt tctaaatcta ttagccttat ccactgatac tttatccatt tctacaagta
    12181 tttcttgttg ctttttagtt atcacatctg ctatcttttc cattaaatca cggcgtttta
    12241 taacaacaaa atgccagttt tgaatattct tgcctgatgg tgctgcacct gctgctttta
    12301 tcatttttaa aatatcttca tctgatacat cttgattttt aaactttctt acactttgtc
    12361 ttttaaaaat agtatcttgt aattccattt ttaaatcccc ccataacttt tttattattt
    12421 taatataatt tttaaactca tcttatttta atatatcatg ttctaacaaa tctttaaatg
    12481 aatctataaa ataatcatat acatctacat tcccaaaccc atatttggca tatataaaag
    12541 gtatacctac aaacttagca ctatttgcat caccttgcgt atcaccaaca tagattggat
    12601 ttattaattt atttctttca attataagtt tattattttc tcctttatgc aaaccagtat
    12661 taccaggaca ttcaaaatct ataaaatact gttctagttt atgtgctttt aaaaaagatt
    12721 ctatatatcc agcttgacaa ttacttacta taaataattt atatttttta gatagtaatt
    12781 taagagtatc ttctatatca tcaaataatt tagctccatt ttcagataaa tagtcacatt
    12841 ctttcaaaga acattcattc aataaattca ttctttcttc ttcacttaaa tttggaaata
    12901 aacgatttgc tatttcctca aaagaaagcc ccataagact tctaaataaa tcttttgtga
    12961 cacttaattc tatttcctta tgctcactta aaacatcctg ccagactttg catacttctt
    13021 cagttgaatc ccacaatgtt ccatctaaat caaaaataat actatctacc acaaaaaatc
    13081 ccccttatgt caaagtttat tatatattta taattatata ctaaaaagca gatacaatca
    13141 taaatatatt ttacttgatt gtatctgctc tacaatataa aaccaattgt caaaatcaaa
    13201 ttttataaat ttctaactac aagtacacag ccttgctcta ctttaatctt acaagaatta
    13261 ctcaacataa catttgatat tccaataggt acagagtatt tcatataata attatcgaga
    13321 gggtattcta agccagtaag tgttacaccc ttagcatcac catttatagc tattacagaa
    13381 atagtgtccc ctgggtttcc atacaatgaa atttcctcat tttcaactat atacatctct
    13441 tctttatcag aaagtatcct agaatatata ccatcttctt ttaaataata taatagcttt
    13501 atatttgcaa gagtgtggtc aatccttccc cctaaagcac caaaaaaatc aatatgattt
    13561 gctttaagtg tcttagctaa aaaaagacaa agctctgtat cagtctcatc ttttttagat
    13621 ggaaattttt caaatttaac acctttattt ttatagaagt ttatcttttc ttcttctact
    13681 gaatctaaat ctcctaatat ataatctggc attatttcca ttttataagt gtgatttgcc
    13741 cctccatctg cacatattat gcagtcataa cattccttaa ttataatatc tcttgtaact
    13801 tcgtaatctt caatttcgcc atttaaaaca atacagattt tcattattaa atttaaacta
    13861 attcttcaag agaagcattc tttctaaata aattaactgt ttcttgaatg tcatcacttc
    13921 caaatattgc agaacctgct actattacat tagctcctgc ttgtacaact tcggctacgt
    13981 ttttagggct tataccacca tcaacttcta tatcaatgtt taatccttga ctatctataa
    14041 tagcttttaa ctctttaatc ttatctaaaa cacaaggaat aaatgattgt cctccaaatc
    14101 cagggttaac agacattaat aataccatat ctaaatcagg tagtacatgt ttaatcgtat
    14161 ctactggtgt agctggatta agtactacac cagcttttat tccatgtgat tttatatttt
    14221 gtatagttct atgtagatga acacaagcct cctggtgaac agttattata tcacatcctg
    14281 cttttacaaa ttcttcaata tactggtctg gattttctat cataagatga gcatcaaata
    14341 ccatatttat attttctttc tttaaacttt tgactacaag tggtcctaat gtaatgtttg
    14401 gtacaaagtg tccatccatt acatcgatat gaagatattc acatcctgca ctttctactt
    14461 ttcttacatc ttctaataat tttgcaaaat ctgctgataa tattgatggt gctaatttaa
    14521 tcatgtttct aatacctcct actattattt tgtcttattt catgtagcag ctgtatataa
    14581 ctatcatatc tttctttaga tatttctcca tttgtaacag cttcttttat agcacaatta
    14641 ggttcatttt catgaataca ctttgaacca aacttacaat cattaaattt atcaaattct
    14701 ataaaataat ctttaagttc aacttcctct atatcttcaa gggcaaggga actaaaacct
    14761 ggtgtatctg caaccattcc accaaattct aattttaaaa gttcagcgtg acgagtagta
    14821 tgttttcccc tttttatttt atcacttaca actcctgttt gaagtttaaa attttcatct
    14881 atttcattta ataagcttga ttttccaact ccagatggtc ctgcaaacac tactacattt
    14941 tcttttaatt cttcttttac tttatctata tttaacttag taatattgct tacaggaatg
    15001 actttatagc cactaagttc atatatattt ttaacagttt ctaatgtatc attatcatct
    15061 aaatctgctt ttgtaaggat tattacagtt tctaaatttt ctttttctgc caaaactata
    15121 aatctatcta aaagagataa gtttggttta ggatttttta ttgcgaatac tattaatgct
    15181 ttatctacat ttgcaatagg aggtcttata agttctgtat ctctactgtc gatttcttct
    15241 aagataccct ttttttcatt ttcatcaaca atgcttattt tgactctatc accaaccaaa
    15301 ggtgttattt tctgctttct aaatatccct ctagccttac attcataaat accattataa
    15361 gtatctacat aataaaatcc actaatcccc tttataattt ttccttctag catcaaatgc
    15421 ctccctttat aaaatttata taaacacata ctgtttatga gtagtatatc gtgttattct
    15481 ttcctatttt tatataatac cacatttttt ttaaataaca aatcctccgt ttggactaat
    15541 tacctgacca gtgataaaat ttgatttgtc tgatgccaag aaaatagcac aatttgctat
    15601 atcttctgga gttcctagcc tcattagagg ggtttcttcc acaagagcgt ctatatcttc
    15661 ctcattatat ccagataaca tgtcagtatt aatgacacct ggagctatgc tatttactct
    15721 aatatttgat ggtcctactt ctttagctaa tgcctttgtc atacctatta tgcctgcttt
    15781 tgttatagaa taatgcactt cacaagacgc acctgatata ccccagattg aagatatatt
    15841 aattatattt cctttttttt ctgatatcat gtattttaaa gcaacttgtg aacaataaaa
    15901 gcttcctttt aaattaatat tcatcatatt atcccaatct tcatcagtta tatctgtaaa
    15961 caacttatct tgacttacac cagcattgtt tacaagtaca tccaatcctc caaattcttt
    16021 tatacaataa tctaccatat cctctacatc ttctctattt gaaatatcag ccttaaaaag
    16081 ttttacagaa aaattttttt catttaatat agtgtacaac tctttagctt cattttctga
    16141 cttattaaaa tttactaata cattgtaacc ttcttttgca aaagctttag acatagcttt
    16201 accaatccct ctagctcctc ctgtaattaa aactgttttc ttcttcataa atacttttct
    16261 ccttatatta taaccaattc agtattttat acaaaacaaa ctgcccttta aagaaaatat
    16321 tttctataaa aggacagctc ttattttatt aatatttatt ctgttttacc aatgtttgcg
    16381 ccagttcctg atgaagttcc tccattatct cctgagtttg agcctcctga actatctcca
    16441 ttgtctcctg agtttgaacc tcctgaactt cctccattgt ctcctgagtt tgagcctcct
    16501 gaacttcctc cattatctcc tgagtttgag cctcctgagt ttccaccact atttcctgag
    16561 tttgaacctc ctgagttact tccattattg cctgagtttc caccactatt tcctgaattt
    16621 gagcctcctg aatttccacc actgtttcct gagtttgaac caggttctgt tggtgtatta
    16681 ttctctggtg ttgttggttt tttatctggt actgttggag tctgtgtatt tgatttttct
    16741 gaacctttgc ttacatatag gtttacctca tcaccttcct gagctcttga tgagccagca
    16801 cccggactct gacttaaaac tgtaccttct ttatatattg agctgtattc atacttaaca
    16861 gttcccactt ttaagttatt ttcttcaata agttgttttg cattactcaa agtaagtccc
    16921 actacattag gaacagatgc ctgacttgaa cctttactta cgacaacatt tatagtatca
    16981 ccctttttga catttgtact tccaccttca ggtgtctgtg atattataca attttcatca
    17041 acttcactat tatactcttc actttttaca ctcaggtata atccttcttt ttcaacagca
    17101 ctttgagctt cttctaatgt catatttaca agattaggaa cagtcaaaga tttattgcca
    17161 aaccctccag caaataaaaa cttatatgct aagaatactt gagcacacaa tatcagtatc
    17221 aaaacagccg caattacttt taatcttctt ctagattttg ggctttcctg ttttttcttc
    17281 tttttcttag ttctcttact tggagtactc ttaggtctct gattcttttt agctctcatt
    17341 atctcttcct cttcttcatc ttcatcatca tcttcttcat aaaaatcatc atagtaatct
    17401 tcatcatcat ccaaatcagc tacttcaaca ggcttaacca ctttttcagg agctggtttt
    17461 gcaagtgttg gatttacaac tttattaatt tctttttcat caattttctt agttgcaaaa
    17521 tcatcatatt cttttataaa atctaaatca atattttttt ctatatactc tatatcttct
    17581 atcaattctt cagcagtttg atatctatct gcactagatt tttctgtaag cttttttatt
    17641 gtagttctta cactttgagg aatcctaact ttttcttctg atgtaaagtc tatatcatca
    17701 ttaatgtgtt gaagtgctat agaaattgga ctatctcccc taaatggaac ttttcctatc
    17761 aacatttcat ataaaactat acctagagaa tacaggtcag cattattagt tacaaattta
    17821 cctttagctt gctctggtga aaaataatgc actgaaccta ttatactacc aatattagtc
    17881 attgttgaat ttgaaacagc tttggctata ccaaaatcag ccacttttac tactcttcct
    17941 tcatttgata tgagaatatt atgaggtttt atatctctat gtataatccc ctttttgtgc
    18001 gctgcactaa gtgccatagc tatttgtttt gttatatcta atgcagtata ttcatctaat
    18061 ataccttcat cttgtataat ctcttttaga ttcttcccat ctacaaactc cattacaatg
    18121 tagtgaactt ttccatcttc accaacatca taaacattta ctatatttgg atgtgaaaga
    18181 cttgctactg cttctgcctc tcttttaaac tttgttagaa attcatcatc atctacaaat
    18241 tcaggtctaa gtactttaag tgcaacagtc ctgtttaata atctgtcttt agcctcatat
    18301 acaaaggcca ttcctccatc accaatcttc ctgatgattt catatcgatt tcctaaaatt
    18361 gtatctccca caatatcacc gtcctaatta tacttttatc actataaccg aaacattatc
    18421 tttaccagaa acatcattgg ccatacttat caattcttca cttatattac tagttctctc
    18481 atattcataa tctaatatta aatctcttat atcttcatca tcaataaacc cagttaatcc
    18541 atctgtcgca agaagtatta tatcactttt tttgatttct ttcttaaaaa tatctacaac
    18601 aaccatatca tctgttccaa ttgctctagt tattctattc ctctgtggat gtcttcttgc
    18661 ctcttcttct gtaatgacat gggccatcat aagttcttca accacggaat ggtctatagt
    18721 tattttatca aatttttcat ctgttaacaa ataacatctg ctatctccaa catttgccac
    18781 atataagaca ttattataca ctatagccgt aactaatgta gttcccattc cttcaaattc
    18841 tatatcttcc atagattttt tgtgcacaat tgagtttaca ttattataag cctgttttaa
    18901 tatatcatct atatagtcta tttttacatt atcatgttgt aataagtttt cctttagaaa
    18961 atcaattata ttttctactg ctaatttact ggcgacttca ccttttttat gtccacccat
    19021 tccatcagct atggcaaata ttcctattgg accatgttct gtatctataa cttctccctc
    19081 acaatagtct tcattgtttt ttcttatttt tcctatatgg gaggcacaac tataaaccat
    19141 acgacttcct ccttacaaat tacttgtatt ttcttctcaa ttgcccacaa gctccactaa
    19201 tatcagaacc catagacatc ctaactgtgg caggtatatt gttcttctcc aaactatccc
    19261 taaatttata aataaatgct ttatctggtt tttcgtattc tctttcttca actttattta
    19321 ttggaattaa atttacatga catagcatac cttttaggag cttagctaat gcctttgctt
    19381 ctttttctga gtcatttacc ccttttataa gagaatattc aaatgtaacc cttctatttg
    19441 tcttttttat ataatatcta catgcattca atatttcttc aatagaataa gcatttgcta
    19501 caggcataat ttttcttcgt tcttcatcat atggtgaatg aagtgataaa gctaaattta
    19561 tagctatttc taagtctgcc aactcataca ttttaggtac tattccacaa gttgaaagag
    19621 ttatatgtct ataccctata ttaagaccat ttttttcgtt aattattttt aaaaattgtt
    19681 ttgtattttc aaagttatca agtggctcac cactccccat caatacaaga tttgataccc
    19741 tcttaccagt atcttcttga attttaataa cttggtctaa aatttcccat ggctctaagt
    19801 ttctaattaa tccatccatt gtagatgcac aaaaattaca tcccatccta caacctactt
    19861 ggttagaaac acagacagta actctactat cataatccat catcacagtt tctattatat
    19921 ttccatcatc taataaaaac aaatattttt ttgtattatc taccttagat tctaacttta
    19981 attctatatc tatatgccct atacatgaaa cctcttctaa tttatttctc aaactttttg
    20041 gtatattgtt catatcatca aaagtttttg cacccttata tatccaagag aatatttgac
    20101 ttcctctaaa gggcttttca tctatagttt tcataaattc tttaagttca tcttcagtaa
    20161 aattttttaa tactatcttt ttcttttcca ttctctcact accttattct ctttaatttt
    20221 gctatgaaaa aaccatctat accatgaata ttaggatata tctttaaata tcctttatct
    20281 tgattatcta agtctacatt tactgtatca attggaacaa attcaaagtt gtgattttct
    20341 tcaacaaaag aagtaactat atttatattc tccacatctt gaattgtaca tgtactatat
    20401 actaaagttc caccaacttt gacatattta gatgcatttt ctaaaatttt cttttgtata
    20461 gaagtgatgt cttttaactc ttcttctttc ttatacttaa tttctggttt acgtcttatt
    20521 ataccaaaac cagagcaagg aacatctgct aaaacataat caaatttact tatactattt
    20581 tcatcaatct cagaagcatc aaatctttct acaaacacat ttttaagccc caatctattt
    20641 acagtagagt ttataagctt tagtttatgc tcaaaaatat ctctagctac tacttgacca
    20701 gtattgttca ttaaagtagc taagtgagta gatttccctc caggagcact acatacatcc
    20761 aaaacaaatg aaccttcttt tggattaatt actttcccta ctatcataga acttatatct
    20821 tgaattgtaa ataaaccagc cttaaataat tcattttttt ctatattttt cattttttcg
    20881 actttaatag cttcttctac cataggaact tttaaacata caatacccat ttcacttaat
    20941 ttttcaataa gttcttctct acttatttta agtgtattcg ttcttatata gatactaggc
    21001 ttttcattat ttgcttccaa caaatcttca gcaaattctt gtccaaattt atctatccag
    21061 ttttttataa tccaagagtt ataggaatac tttatagata agtattttac actatcttcc
    21121 tcagttatgt ccattatagt ctctttagct cttatttcat ttctaagaat agcatttatg
    21181 aaaccagaag attttttatc atatttctta gataatttta cagtttcatt aactgctgca
    21241 taatctgata tactatctaa aaataaaatc tgatatgttc ccattcttaa aaagatttta
    21301 acataagttg acattttttt tacctttatt tttgaaagtt tattgattat ataatctaaa
    21361 taatatttat tttctattac tccataaatt aactctgttg caagtcctct atccatatca
    21421 cttatttcta aatttttaaa atgcttattt attgcaatat ttgaataatt gtcatttttt
    21481 tctatatcac ataatacttt aaatccaact tctcttgcat ccatataaat ttctcccttt
    21541 tattaaacat aaaaaagggt tgtttctaaa caacccactt tacttttagt catttcttct
    21601 ttgagctatt agtaacaatc taagtaattg aagtattgaa accaatgctg ctgcaacata
    21661 tgttaaagct gctgctgaaa gtactcttct actttgtctt gactcacttt catctataat
    21721 ccctaaattc ccaagttgaa cgattgctct acttgaagca ttaaattcta caggcaatgt
    21781 tattatttgg aataacactg aagccgaaaa caatagtata ccaattttta aaaatggacc
    21841 agccataata aatcctaaaa atattaaaaa ccaagatata cttgaagcaa aattcactac
    21901 tggtactaaa ctacttctta tttgaagagg tgcataacct ttagcatgtt gtatggcatg
    21961 accacactca tgtgcagcta ctgcaacaga agttatagat gttccataat atacatcttc
    22021 tgacaacctt acagcctttc ttcttgggtc ataatggtca cttagatgcc ctctaaccat
    22081 ttctatcttt acatcataca aaccatttga atcaagtact cttcttgctg tttgctctcc
    22141 agtatatcct cgacgtgtat ttactcttaa atacttattt gttgttgaac tcactttaaa
    22201 ttgtgcatat atagtaagta atatagctgg aattaataca accattgttg ggtcaaatcc
    22261 ccaaaaaccg ccatatacag ggtacataaa taacactctc ctaaaatata tttttattat
    22321 acatcctctt aatattcact taacttaaaa acagtttaat tacaaactaa tatatttttt
    22381 cctgttaaaa agcctatagc tttttcaata tccatcatgt ctacattagt atttacacaa
    22441 ggtccattag gtcttttgtt aaatacacct aaaacaggaa tttttttaat atcttgtatt
    22501 ccagatgtca aatctctttc acatgcaaca gctacaacag ctttaggttt agtgtccatt
    22561 ataatttttc tagctagggt tcctcctgta gctacaaata tttttacatt agttttttcc
    22621 tttagcttaa ttaattctcc tatgttgcat cttccacatt ctttacaatt atctatatca
    22681 ttagtaactt ttaatttaca actattctct tgaatacaat gaggtattaa aattattata
    22741 tcctctggat taaaattata tttattactg tatatatatt cattatttaa ctttatatat
    22801 attcttctaa tatcactttt tgacatacca aatgatgatg caatgaaaga tataatagga
    22861 aataatccac tgacaatatt aaaatttatt ttcattatat ttgagttaac atactttcct
    22921 ttaattactc tataagtaac tgctgttgaa catagtatta taagtattag tgatattatt
    22981 ataatattta tcatcaagga gaatatttga gttaaactta ttataaaaaa attaacaact
    23041 cctatcaaaa ttcctaatat taaaatcaaa atcccaacac ttgttaaata cttctttata
    23101 tctgtcatac ttttcaccta acccaatact aaaccagttt ctatagtatt cccttttata
    23161 tattcaccaa ccaacattct ctttttattc ggcatctgaa tttcttcaat taaaagtaca
    23221 ttatctatag tacttacttt tatcccatct ttgcttacat caattattgt acctacatct
    23281 tttgtgcttt tttcatctaa cactttagtt ttccaaactt tcattatgac atcattatag
    23341 gtagtataag cacttggcca tggatttact cctctaacta aattgtgtat ttctctggca
    23401 ctttttgaaa aatctatgtt acctaatgat ttattcatta ttggcgcata ggaaaattct
    23461 tcatgatttt gtacttctct tggagcattt ccttcttcaa ttaatcttaa tgtttctttt
    23521 aaagtttctg ctcctatatt catcatttta tcatgaagtt ctcctgctgt tatattttca
    23581 tcaagattta cttctgtctt tagtatcata tctccagtat ctaatccttc atccatatac
    23641 atagttgtaa caccagtctt ttcttcacca tttattatta cccaatttat aggtgccgca
    23701 cctctatatt ttggaagtaa agaaacatga acatttatac atccaagttt aggaatctct
    23761 aatatttctt ttggaagtat ctgtccaaaa gctacaacta ctattacatc tggatttaaa
    23821 gatttaattt tatctataaa ttttttatct ctagccttta ctggttgata tacaggtata
    23881 ttattttcaa ttgccagttc ttttactggg ctcataccta gttttttacc tcttcctttt
    23941 ggtttatctg gttgagttac aacacccaat atttcatact tctcatctat tattttttgt
    24001 aaacatggaa ctgctatatc aggagttccc ataaatacta ttttcatcaa atcaactcct
    24061 actacttttc tattttgtca acaaataaaa ttccatctaa gtggtctatc tcatgacaaa
    24121 atgctctagc taaaagttct tctccctcta actctattgt ttcaccattt ctatttaaag
    24181 ctctgacctt tacataattt ggtcttctaa catttcccgc ttctccaaca acacttaaac
    24241 atccttcctc atctatttgc tccccagatg tttctattat ttcaggattt ataagttcta
    24301 taagctcttc tccaatatct attactacta ctctttttaa tattccaact tgaggtgcag
    24361 ccagtccaac accatctgca tcatacatag tttctgccat atcatctaat aattgtatta
    24421 tcttttcatc aattttttca accttttttg atttttttct taatactggt tctcctattt
    24481 gaactatttg tcttaaagcc attataattc ctcctaaatt tataatacac tgtttggatt
    24541 aatatctata gatacattga tattcttatc aaatatcaaa tctcgttttg ttatacatat
    24601 atattttatt atacccttta agagattaat ttcaatattt tcatctttaa agagtatttg
    24661 ccatctataa ttttgattta tttttgatat tgaacatgga tttggaccta atataaatcc
    24721 taaatcattt ataccccttt tttctaataa ataaatcaat gatgcatgca tattttttat
    24781 attttttatc actaatcttt catcttcacc actaacaact acacttaaca tattattaaa
    24841 aggagaatat ccaaatgctt ttcttatttt tatctcatct tcataaaaac cctcataatc
    24901 atattcaata gcatgcttaa tggcatagtg ttcagtgtca taagtctgaa gtactacttt
    24961 tccctcttta tcagctctcc ctgctcttcc agagacttga gttatcaatt gaaatgtagt
    25021 ttcaaaactt ttaaagtctg gaaaatttaa tatcatgtct gcagacaaaa tacctactaa
    25081 agttacattc tcaaaatcca gccctttact taacatctgt gttccaataa gtacatctgc
    25141 ttctttatct ttaaatttat ttagtatctc atctaaagca cctttttttg aagttgtatc
    25201 tttatccatt ctcaaagttt ttatatctgg aaaaatatat tttaattcct cttcaatttt
    25261 ttgagttcca actccaaatg gcttaacata agtactttta cattcaggac actcttttgg
    25321 aatttctttc tcatatccac aatagtggca tcttccagta ttgcttttct tatgataggt
    25381 taaagatata tcacaatttt cacattgaaa cacatatcca cactttctac aagatacaaa
    25441 atttgcataa cctcttctgt ttaaaaatag tattacttga ttattttctt caatcgcata
    25501 acgtatttct ttttgtaatt tcaaactaaa tatacttcta tttcctttat ctaactcatc
    25561 tttcatgtct acaacttcaa tgtttggaag aggcttatca tttgctctac tttttatatt
    25621 tataagtttg tattctccag attttgccct ataatactct tcaattgagg gcgttgctga
    25681 acctaaaata agagttatat tattttttaa tgccataaat ctagcaactt ctatagcatt
    25741 aaattttgga ttcttctcag acttatatga tgactcatga cattcatcaa ttattattaa
    25801 gcctaaggaa ttaaaaggtg caaataaagc tgacctagct ccaattaaca ctcttacttt
    25861 acctgctttg acagctttgt aaacatcatg tttttctcct tcagatagtt tactgtggaa
    25921 cactccaact aaatctccaa acctactctt tagcctatct attgtttgag gagttaatgc
    25981 tatctcaggt actaagaata tactgtctaa gccttgattt agagcaaatt ctattatttc
    26041 catgtaaact tcagtttttc cacttccagt tactccatga attaagtatg gttttttatc
    26101 atctacaaac atattcgact ttatctcatc aactgcttct tgttgctcat tgtttaattt
    26161 tatacttttt agtacggatt tgtaaatact ttttggcttt ctataataat ccttaaattc
    26221 tagggttatt agctttttct tacttagaga atttatactt tgttttgaag catttaataa
    26281 atccaataaa tcatttatct ctacattttc attattttta agaaaactta atatctcttt
    26341 ttgtttactt cccacattta ttttattttg ctctatataa tcgtcaatct tatcactttc
    26401 taaactcaaa gatatataac atactttctt ttcatttttg tgatttttat attcccaaca
    26461 taattttata attccatttt tattcattgt gtacaaagaa ctatttaagt ttggtatata
    26521 ttttaactta tcaaccttaa ttttaccttt actatcaatc actttctcta ctatttctct
    26581 atttttatca cttaaagttg atattttttc cttcaattca atatcattta atccacttaa
    26641 actttcacct aataggacta ctttataatt atttaatttg tatccctttg gatatatcaa
    26701 atttatacat tctatataag tacacaaata tctatttttc atccaataaa ccaactctaa
    26761 atcttctttt ctaaatatcg gattttcatc taatatatca ataatttctt ttatttttat
    26821 tttttcatct aagctatctg taaattgaaa tacaaaggct tctgttggtt tattaccttt
    26881 tccaaatggt actaatattc tgtgcccaat ttttattaca tcagataaaa atacaggaat
    26941 ttgatatgta aataaattat ctgtatatat agtattactt ctaactatta cctttgcata
    27001 ttttttcatt ataaaacctc tacttaaatt taatatattg ttcatatttt aatatacttt
    27061 acaagatatt aaaatttcag aatttataaa caatttcaag ttattaatat taactttatt
    27121 ttaataatta actattaatt atattttata ctttatgaca aaataaatgc tgaaaactac
    27181 aatttaactg acatttgcga gtttttactc gctaaaatta aattgcagct ttcagccact
    27241 ttagctgtga taaaatacac aaatatcata tttaaaaaag gtcttatttc tcaagcaacg
    27301 ctttaacttt atctaaaata acattggcta cttcttcttt tttcatctta ggatactcag
    27361 taatatttcc ctctacatct attattttta caatattagt atcagctcta aaaccagcac
    27421 cttctttagt taaatcattt gccacaataa aatctaaatt tttctttttt atttttcctt
    27481 tggcatgttc tataaggtca ttagtttcag ctgcaaatcc aattagtatc ttatcttctt
    27541 ttatttttcc tatttcataa gcaatgtcat aatttctact tagttctatt gataaatcat
    27601 cattcttctt tttaattttt ttgtcagaat aagtttttgg tttataatct gcaactgctg
    27661 cactttgaat tactatttta ttttcactta aatttgatac tactgcttca tacaaatctt
    27721 gtgctgactc tatttgaaca aattttttaa gattttgtgg aatagaaaga tttgtaggac
    27781 ctgatattaa tgttacatca gcacctctag ctatagcttc tcttgctata gaatatccca
    27841 ttttaccaga agacctatta gttaaatatc ttactgggtc tatactctct acagttggac
    27901 cagctgtaac tatcatactt tgacctttta aatcttgctc tttagtaaga ttagtcaaaa
    27961 cttcctctac tattatatct ggattagcta gtttacctgt tccaatatct ccacatgcaa
    28021 gccttccact ttccggttca ataaatttat atccaaagct ctttaaagtt tgtatatttt
    28081 tttgaacaat tggattttca tacatattag tattcatagc tggtgctata agaacctgtg
    28141 cttttgttgc cataacagta gttgtcaaca tatcgtcagc tataccattt gcaatcttgc
    28201 ctataacatt tgcacttgct ggcactatta agaataaatc tgcttttttt gctaatgata
    28261 tatgttcaac ttcccaagtt tttggttctt caaacatatc ttctactaca taattttgac
    28321 tcagcgattg aaatgtaagt ggtttaacaa attctgttgc tgattttgtc attataacat
    28381 ggatatttgc atttagtttt tttaacttac ttacaacatc acaagcctta tatgcagcta
    28441 taccgccact tatgccaatt acaacagttt tatcttttag catgacctta ctcctcttct
    28501 gaaatttgtt ggtgttgctc agcatgatgt ctagcttctt ctatctctat ttcctcttct
    28561 gtcaataatc tatatgttat ttttccactt gcaacttctt tagttgctac acatacaggc
    28621 ttttccttag ttttatttga aacatatggt tcttctccat caattaattt tcttgctctc
    28681 tttgaaacag tccctactaa atagtatctg ttgtctattt tttctagtac ctcattgata
    28741 gatggtttta acataattat aattcctcct taaatttctc tattataata tttttatatc
    28801 tgctaacttt attcttttca gatgatatta taccttctat ttctttagca gatgttttta
    28861 catcttcatt aaatataaaa taatcataat ccttaatcat tttaatttct tcatatgcac
    28921 agctaaatct cttctctatt tcagtttctg tttctgtacc tcttccaaca attctatttt
    28981 ttaattcttt aagtgatggt ggtagtacaa atataaatac tccctctggg caaacttctt
    29041 ttatttgttt tgctccttgc atttcaatct ccagtaatac atcttgtcct ttttctaaac
    29101 attccattat tgccgctttt ggagttccat aaaaattatc ataaatttga gcatactcca
    29161 aaaactcacc tttttctatc atctcttcaa acttttcctt acttatgaag aaataattta
    29221 ctccatcaac ttctccagtt ctgggttttc ttgtagtagc tgatacagaa agttttattg
    29281 tatcattttc tttaagtagt tctttgcaaa tagtaccttt tcctgcacct gatggtcctg
    29341 atacaactag caataatcct ttttttacaa acatttaagc attccccttc taatattgta
    29401 ttcttactct atattttgta tttgttctct tattttttcc aattcgcttt ttacttctac
    29461 tactaaatta gttatattta tatcagatga cttcgaacct atagtgttag tttctctatt
    29521 catctcttgt attaagaaat ctatttttct acctatagag tcgtctttaa atatagtatt
    29581 tttaagttgc cctatatgac ttttaaatct aactatttct tctgttatac tgcttttatc
    29641 tgcatatatt gcaacttctt gtgctaatct attctcatct attatacttg ggtcatccag
    29701 taattcactt attctcaaat tcaatttttc tctataatct tctacaacac tacttgaata
    29761 tttttcaatc tcttctatat gattttttaa taaatcacat ctcatggcaa tatcttcagc
    29821 taatttttta ccttcttcac ttctcatttc tcttaatttg attaatgcat cttcaactgc
    29881 ttgattcaac attgaccaca ataaatcttc atcttcttcc ttttcttcta ttttcacaat
    29941 atcaggaaac tttgcaacat tcataacgct aatatcatct ataatatcaa atttattttt
    30001 tatttctttt agtatgtcta tatactgaga tgctaatccc tcatcaaaat ttaagtttac
    30061 atcttctttg cctaataagt caaactttat gtataaatct actcttcctc tttttacata
    30121 attttttact aaatttctaa ctttatcctc taaaaatgaa atttttcttg gaatacgtat
    30181 gtttatatct gaatacttat gatttatcgt tttacactct actaaaaagt aataattatc
    30241 atccttgtat tctcctcttc caaaaccagt catacttata gccattaatt aaacctccaa
    30301 aataccttca catattttta ctgctggacc tgtcatataa gagaaatctc ctacatctat
    30361 tttaactgtt ccaccttgag acgttacatt tacactactt tctaccatat ttagtaaatt
    30421 gcacactatt gctgatgcag tcataccagt accacaacct aaagtatatc cacaacctct
    30481 ttcccaagta taaacatgta tattatactt atcttctacc tttacaaaat ttacattcgt
    30541 tttttcagga aatattttat tattttcaat ctcttttcca tatttacaaa catcatctac
    30601 atctaattca tctactataa ctactgtatg aggaaccccc atcaacatag aagtaacttt
    30661 aatctcccta tctaaaacct ttatactttc ttgcacaaaa cgttctttat ttgtaagtac
    30721 aggaacgtct ttagctataa aacttccttt tcccatattg actcttatag agtttatttc
    30781 tctattggta agatttattt ttatatcttt tataccatct aatgtatcta ctgtaaaact
    30841 ttctttttta actatacaat tatcataaac aaatttacaa aaacatctaa ggccatttcc
    30901 acacatagct gctcttgaac catcagaatt ataatatacc atttctacat ctgcaacttt
    30961 tgaatctttc acaactaaca atccatccgc tcctacagaa aatcttctat ggcatacttt
    31021 ttttgctaaa gcagtataat cagatggatt tatctggtcg aatcttccat ctattgctat
    31081 aaaatcattt cctattccat gtagtttcca aaatttcata agtatcgctc cttcgtaaat
    31141 taacgcttaa actattataa cataaaaaaa ttcccataaa cttataattt atgggaaaag
    31201 ttttgtaatg acaactataa tttgaggatg tgagggagag ttgccattac aattagggta
    31261 attatattat gtttttaagc tagttctttc tatgtttata tattaatatt tctatatgaa
    31321 ttttatgtat gttttattta aactgtctat gaatttttta attaaacatc tggtaactag
    31381 ctataatcct tctagtagat atctattaac atacacctat taattcttta agtgttttta
    31441 aaacatagtc taaatcttcc ttagtaatat ctacatgagt tacaaatcta tattcaccat
    31501 tttccatttt attaattttt atatttcttt caaaaaattc ttttattaaa acatcctctt
    31561 ttataatatc ttcactcatc ttaaaaaata ccatacttat atctggatta acattgttta
    31621 cttcaatgcc atcaatttta tttaattcac aagctaaata ttttgcattt tcatggtctt
    31681 cattcaatct taaagtcatt ttttcaatgg caattatacc agctgctgca actataccta
    31741 cttgtctcat tcccccaccc ataacttttt gctttcttct agcttttgct ataaattctt
    31801 tatttccagc aagtatagaa cccattggtg cagctaaacc ttttgacaca cagaacataa
    31861 cactatcaca acactttgct atttctttag cttctacacc caaagttaat gctgcgttaa
    31921 ataatcttgc tccatctaaa tgtactggta agttatgttt ctcagctatt tttttaattt
    31981 ctcttaaatt atcaagactc acaactgttc cacctgaata tgcattttct acacatataa
    32041 gccctgtctg tggttcatgt atgtcatctc ttctaattgc cttttcaaca agttcaggat
    32101 ttagagctcc actttcgtct tcatctatag ttctaagctg aactccagct attacagcag
    32161 gtgccccaac ctcatgagtc acaatgtgat aacctttacc aataattatt tcttgccctc
    32221 ttaggcaatg agtaaataga gctaattgat tcccaaaagt tccacttgga aggaaaatag
    32281 catcttcttt tccaacttta gctgctgcta attcttcaag tttatttaca gtagggtcat
    32341 ctctaaagat tgaatctcca acaggagcct ttgccatagc ttctctcatt tcgtcagtag
    32401 gcatagtaac agtatcactt cttaaatcga taaatctcat tttttcaacc ttctttcata
    32461 tttatatatt atagaacctt aaaattgatt ttttctgtaa agttcatata ctttcatagc
    32521 ttatactcta cacaataatt atactatatt tactttatat ttaatctact ttaaattatt
    32581 aattttaaaa ataaagtttc ctctctaata aatataaata atcatacaat ttaaatatta
    32641 atctctattg tttaaattcc ctctagtcac aaagcgtata ttatgtgtat aattaattta
    32701 ctgactcatt ttggtcaaag aaaggggtgc tataaatggc attagatgga ttagttatac
    32761 attcaatagt cgatgaatta tcatcaaaac ttacaggtgg aaaaatagat aagatacatc
    32821 aacctgaaga tgatgaggta atttttaata taagaaataa taaagaaaat tttagattgg
    32881 ttttaagtgc aagtgcctca aatcctagag tttatcttac aagtaattat caaaaagaaa
    32941 accctctaaa agcgcctatg ttttgtatgt tacttagaaa atacatacaa ggtggaaata
    33001 tagtagaaat ttctcaaata ggttttgaaa gaataataaa aataagcgtt gaatctttag
    33061 atgaattaaa agaaaagaca gttaaaaata ttatgattga aattatggga agacatagca
    33121 acataataat aactcatggt gaagaaaata aaattataga ttctataaaa agagtccctt
    33181 ttagcataag tagagttcgt caagttttac ctggtcatga ttattcatta ccaccagaac
    33241 aaaacaaact caaccctctt gatgatatat ctaaggattt gtttattaaa aacctagagg
    33301 aattggaagg acctatcttt aagtctatat attctagatt tctaggtata agccctatta
    33361 tagctaaaga aatttgctac agagcaggtg taaatcaaaa tgctatcata aaggatatat
    33421 ctgatgaaca atttgattct ttacacaaag tattttgtaa tttattcaat gatataaatt
    33481 ctaacaaata ctctccttgc attattatag ataaaaaggt ggataaggta gttgatttca
    33541 gttgtataaa ccttacatta tttagcgatt tatcatatat aaataaggat agtatgtctc
    33601 gtattctgga agatttctat agaactaaag atattaaaga tagaattaat caacgttcat
    33661 ctgatttaaa gaagagtata tctgttaagc ttgatagact ttataataaa cttaaaaaac
    33721 aagaagaaga attatcagaa tccgaaaatg cagatattta taagataaaa ggagaattga
    33781 ttacttcata tatttatatg gtagaaaaag gtatggaaag tattgaagtt gctaacttct
    33841 atgatgaaaa ttgtaatgat gtaacaatag aattaaataa aaacttgaca ccatctgaaa
    33901 atgctcaaaa atactttaaa aagtataaca aaatgaaaca tgctaaagtc gagatatctc
    33961 atcaaatttc cttaaataag gaagaaatag attacttaga aaacataatt ttaagtattg
    34021 aaaactgtga aaatttagct gaattacaag atataaaaga agaacttgct aaggttggat
    34081 acatcaagac tcaaaagaaa aacagtaaaa aggatactat cccatctaca aaacctcatg
    34141 aatttgtgtc ttctgatgga tttaaaatat tggttggtaa aaacaataag caaaatgact
    34201 atcttacact aagacttgct gataatgatg acttatggat gcatacaaag aatattcctg
    34261 gttctcatgt aataataaag tgtgctggta aggaagtccc tgataatact gtatttgaag
    34321 gagctatgct agcagcattc tttagtaagt caaaactttc ttctcaggtg cctgtagact
    34381 atactaagag aaaaaatgtg aaaaaaccta gtggttctaa accaggtatg gttatttatg
    34441 aaactaacag tactatttat gttactcctg aagaagaaac agtagccaag cttaaggtta
    34501 aatctgaata aattctgcac taaatacaaa ataaatgtta gacaactaca cattatcatt
    34561 ctaaataaaa atagtggcct tcttataaag tacaataata aggccacttt ctaattagct
    34621 tacttttaat tttctaacaa aatacttttc tgttttaata actatactta tattcccaac
    34681 aaatattttc agtcttctta tatagatgta attaaaaagt taacactaaa agctattttt
    34741 taatttattg atttgtttta gtaattcatt atattctgat tcatacaatt ctttttttag
    34801 attatctttt tctatagata acatagatat aacagttgta agtctatttt ctaatactag
    34861 aagattttct tttttgattt ggttttctct actaggagtt tttttatttc tgctaattgt
    34921 atattcgtca taattacaat caaactccct tattttagca tcttttatct ctataatata
    34981 gttacaaata tgtgatacaa atactctatc atgagacact ataagcatag ttttatcagt
    35041 atttatcagt gccttttcca gtgcttccat agattttata tctaagtaat ttgttggttc
    35101 atcaaatact aaaaaattat tatcttccaa tattatttta catagtgcta tttttacctt
    35161 ttctccacca ctaagtactt ttactttttt gtagacatca tcacctttaa acccaaatag
    35221 gcttaagttt atccttataa aagattcatc aaatgaacta ttaactttag tattgtatag
    35281 aacactcttt tcctcatcta ataaactttg attttggtca aaataaccta cttttacctt
    35341 gttatttatt tttatattgt catttttatc agccaatatt tcttttatca gagtactttt
    35401 tccacaccca ttatcaccta ataatgctat ctttttacct ctttttatct taaaggaaac
    35461 attatctaac aggagcttat tttctaactt tagagtcata tcttttacct ctactagatt
    35521 tttgctaatt atctccatac catcttgcat cttaatgttc atttctttag aaactttagg
    35581 tttattcttt acctcaagtt tatcaattct gctttttata gccttcacat ttgagtccaa
    35641 ctttttctta ttagtctgac cacccatttt gtgcaaccta gcttctgaat tacccattct
    35701 ttttggtgct tttcttatgc catcacttaa agctttttta tataaaagag ctttttcaag
    35761 cctttttttc tctttaacat attcttgata ctcaaaatca gctcttttta cttcttcatc
    35821 tttttgcatt aaataatcag tgtaattgcc tttgtaagct tttagttttc catcttctag
    35881 ttctaatata gttgtacata actcatccag aaaacgtcta tcatgagata ttaataataa
    35941 tgctccctca tgccttttaa acatatcttc caaaacccca atgctttttt tatctaagtt
    36001 tgaagttggc tcatcagcta ttatgatatt tttcttatta ctcagcgcat ctgctatttt
    36061 taacttaacc ttttcccctc ctgataagtg ttcttcaaat ttatctggag catttaaaag
    36121 actcttctcc ttactatgac tacatgtttc aatattattt tcactctgac ttatataaga
    36181 atagctttct gtaaggtaag tatatccttc atcaatttct atttctccca atattgcttt
    36241 taataatgtt gtttttcctt gaccatttga accaactaga cctattttgt cattttctaa
    36301 tatttcaagt ttatctatat ccaaaattaa tttatctgca taatatttct ttaaattctc
    36361 tacttttact aacaacataa aaaatccctc cttaacacac ttaaatataa ggagagattc
    36421 tataaatagg cataacaaat aaacgtatag actataatct actctcctta atttaagcat
    36481 tgcaaataaa gccaccaaaa taggcttttc aaaaattaca atactttaaa ttataaaaaa
    36541 tagattatat tctcattgtc ctagttacct tgccctttct ttcatttatt tttaatcatt
    36601 atatcaacat taattacaaa tgtctataga aaattaacta attttagtta ttcaatatac
    36661 aacttattct ttaaatttat tcttcttcaa ctttaaagtc ctgattattt aaaattctgt
    36721 ttaatacaat tccaacaatt gcagctaaac taagaccagt tatctttact gtacttgtta
    36781 tagggattcc aacagaaata cctttattag ataaatatgt tgttccaaga cctattaata
    36841 atataactgc tatgattaat atatttattt tactttctac acaagaactg tcccttatag
    36901 tttttaatcc tacataagtt atcatcgaaa atagcattat actaattcca cccataactg
    36961 aacctggtat actttgaaga aatccaccaa acttgcctac acatgcaagc aatatagcaa
    37021 atattgctgt acgtctaagt attgaagggt catagttttt agttatagca agtactgctg
    37081 tattttctcc ataagttgta ttggctggtc ctcctaaaca ccctgcaact atagtcgcaa
    37141 atccatcccc aagtaatgtt ctatttaatc cgggattttc tataaagttt ttacctacta
    37201 cagcaccatt agtagtcata tctcctatat gttccataaa tacagctaat acaactggag
    37261 atataatcac aattgctcct aaactgaact taggaactgt aaagttaggt attgcaaata
    37321 aacttgcttc tgtaatagta gttatatcta ctaatcttaa tatcaaacag attatatacc
    37381 cagaaaaaac tgctattaat attcctaatt gttttataaa tcctctacca aacttattag
    37441 ttaaaattgc tattgctaaa gttataaatg ctatcacaaa attggctgaa gccatactaa
    37501 aagctgttgg caataaattt aatcctataa ctactatcat agctcctgta acttgtgcag
    37561 gaaaatataa tttaatttta tttacaccaa ctacttttac tataatcgac attataatat
    37621 aaattaatcc tgctactatt ataccacctt gagcatatgc taaatctcca ccatacgcct
    37681 ctttagctgc tagtataact ggtataaacg caaaacttga acctaaaaag gcaggtactt
    37741 ttccttctgt acaaaaatga aatatcaatg taccaacacc agcacagaaa attgcaactg
    37801 acggattaaa acctgtcaaa atgggaacta atactgtcgc tccaaacatg gctaatagat
    37861 gttgtaaaga cattatcgtt tttttcataa aaacctccaa aattattata tataaataaa
    37921 tcctctgttt aattaatatc ttttaattaa ttatcattcc ctagattcta ttttttaacc
    37981 tctatatact tattatataa tttatcatta ttttacattt tacgacatca aaaactcaaa
    38041 taaaagagaa taaaaactac attaagactc acatccataa aattataata tttattttgt
    38101 gcaatctatg taagctttat cctcctccct gactattcaa tgctaagctt ttatataata
    38161 cttaaaaata attattcttt gattgtaact gaatcttctc catcaatttc taataaactg
    38221 acagatataa tttcatgtct agaagtaggt acattttttc ctacataatc tgctcttata
    38281 ggcaactctc tatgccctct gtccactagc actgctaatt gtattgattt aggtcttcct
    38341 atatctataa tagcatctag tgaagctctc acagttcttc cagtgtataa aacatcatca
    38401 actaaaacta ctgtcttatc atttacatta aaatctaaat aagttccttt aactacaggt
    38461 tcaacatgaa ttttttccaa atcatctcta tacaaagtta tatcaatatc tcctgtatct
    38521 acttttgttc cttctatttg ttctattttc ttagaaattc tatttgcaat tggcacacct
    38581 ctagtcttta ttccaactaa aactagattt tctacacctt tatttctttc aattatttca
    38641 tgacttattc tagtaattgc tcttgctatt gccttttcat ccattaattg agctttttct
    38701 accatatcat aattattgtc aaagatataa tatatctatt tgacaaatct actcctttct
    38761 tttaattttt tataaattta tttttattta aaatttcaat ttaaacaaca aaaaaacttc
    38821 tcatcacaag acaagaagct cttatataaa aaatatacag tgcaatttag caattgtctt
    38881 acgatatctc tgtatcgttt aaagataatt ttttaatcta tcaaatcaaa ttatatattt
    38941 atatttcaaa tttttcaagc ttttttaaac aaaatacttt aatataagat attttattta
    39001 aatttcacta aatttattta cttatataaa aacaaaaaat gatttataag tattatacaa
    39061 atggttattt tatcttttta ataacttcct taaaatactc aggtaattct gaattaaatt
    39121 cgatatattc cttagtagta ggatgtataa atcccaactt cttagcgtgc aaagtttgtc
    39181 cttttaattt aaatttagtt tcttttggac catatacata atcacctaaa agtgggtgat
    39241 ttatagacaa agcatgaact cttatttgat gagttctacc agtttcaagc ctagctctca
    39301 tatgtgtaaa cttatcaaat ctttctacaa cttcaaagtg agtgattgca ttttttccat
    39361 cttttactac agccattttt aatctatcct taggatttct ccctataggt ttatcaacag
    39421 ttattttatc ttctttaacc acaccatagc atataaattc atactcccta gttatagtat
    39481 gttcctttaa ctgttctgct agaaaattat gtgcataatt gttcttagct atcataagaa
    39541 gaccagaagt atctttgtct attctatgaa ctataccagg tctaataact ccatttattg
    39601 atgacaactt atctttacaa tgatataaaa tcccgtttac taacgtattt tcatagtttc
    39661 caggagcagg atggacaacc atatcctgag gtttatttat tattaagaca tcatcatctt
    39721 catatacaat atctattgga atatcttgag gtaaaacttc taatacttta ggttctggta
    39781 tctctataac aatattatct tcctctttaa ccagatatct agctttttct actttattat
    39841 taacctttac ttttccatct tttataattt tttgtatata acttcttgac atatcaccta
    39901 attgttctgc tagataaata tcaagtctaa cttcttcttc ctcttcaagt actaaaaact
    39961 cttttacttc atccattata tcacctactt ttactttcaa aaaataaaac atatatacat
    40021 aaaaacacag ttcctacaac tacaaataca tcagctatat tgaatacata ttcccatata
    40081 attctaaagt cgaagtaatc tactacaaaa cctaatcgta ctctatcaat tagatttccc
    40141 aatgcaccag atataattaa tataattccc aaccttccaa atatatgtac tttccttgta
    40201 ttaagatagt atagtccaaa tactgttgca agtaatgcaa caattataaa tatccattga
    40261 ttattttgta ataatccaaa tgctgcacct ctattttcga cataagttaa atgaaataca
    40321 ttatttatta ttggtattgt tgatacatcc accaaattat tcaataccca tattttagac
    40381 agttggtcta aacctatgag tagaattatt attaatatat atagcaatga tttttccccc
    40441 tataaattat ttaaaaacca attttatttg aagcacacta ttattattat acaaaaaaaa
    40501 tgctctaaag agcaacttta ttaaaattgt attttcttaa taaagctaga acaaaattta
    40561 aaatagtact acttttttta tattgtagat ttctacatat ttaaaatcat atcattatgt
    40621 ataaaaaatt taaaaatacc atactaatca atattttttg tgtattttat agattaaaga
    40681 ttaatgatgt ctgtaattta aacttacaat caccactaat cttcaaacaa atatttttac
    40741 ttttgcactt gcttattttt atctaaatgt tgtataagtt cagatactgt tacgaattta
    40801 tatcctctct cttttaattt aggaattact acttctaaag cttgtatagt ttgtgattta
    40861 tcatttcttt tagtgttata atcatgtaaa agtattatat taccattttg gacctttgta
    40921 aggatagtat ttataattgc atctactcca gggttagacc aatctctagg gtctaagttt
    40981 gaccaaagaa ttatattcat gcctttagaa actataatat cacagacact tttactcatg
    41041 gctctatatg gaggtctaaa tatctttggt tctactccta ttacactttt tataatattt
    41101 tgcgtatctg ttatttcttt ttcaacacta ctataactat tttttgcaac atttatatgt
    41161 gtaaatgtat gattccctat ttcatgcccc tcatcatatt gtctttttaa taattctttg
    41221 ttatattcta ctttttctcc aactacaaaa aaagttgctt ttacatcatt tttctttaat
    41281 atatcaagta cttgtggtgt aaaatcctca tctggaccat catcaaaagt caatgctaaa
    41341 attttttcat cctcatttcc tttttttatt attacatctt cataatcgtc ttttatattg
    41401 tcatttaaac tatatgcttc ttttgaacta tcttgattat gtgtattatg attatatgta
    41461 tatacaccta ctatagataa taaacatata catatacccc atattatttt cttcatgtca
    41521 ttacctcttt tctaattcat tctagcaata tattttataa tgtcagtttt ttaatctctc
    41581 aatattccat ttttatttaa atcagttaaa tttgttaggt cttctgaata aaagttagaa
    41641 tcttctacat cagggttttg cattgcatca cctaataaat tattttcttt ctttgcacaa
    41701 tcattacata aacttgtatc tggcaatata tccaatcttt ctaaatctat ttgattatga
    41761 cataaatcac aaatcccata tgttccattc tctattttag ataatgctaa gtctatttga
    41821 tacaatcttc cctcttcatg atttattaga ctgttttgca tattttgcat atataaatct
    41881 gttcccatgt ctcctatatg attatcataa ctagataatt ctcctgatga atacttttca
    41941 cttgtatgtt tagttgtatc tccaaataga gtattatctt tcatatcctc tactaaatta
    42001 gttaaatttt ctctttcttt caataattta tctttatatt ttttagtatc catttttaac
    42061 acctctaatt ttaatattta catcataaaa atagtatgtg gaaaagtaaa ttaaacatac
    42121 aataaaaata agatttgatt cgaaaaatgg aatgtctcaa aatgaaattt ttagttcatt
    42181 taaccctctt ttttatatga aatcaaatat atttttatcc tttcagcaat aaaaaagaga
    42241 cttatctcta ttttgagata gtctcttctt tgaacataat ttaaatataa ttttttaatt
    42301 tttatagtta ttattttact aacttgccaa tttatgatta ttttgttctt taatatgttt
    42361 tgctttttta aagaataaaa gaccaagaat tattgctaca ataacaccta ttccattaga
    42421 tatattaact ggtagtctaa atccttcttt tgcttgcatt atataactaa atgttactac
    42481 agtcataaaa agtgctggta atgtagttat ataatggttt ttatttgctt tgactaaata
    42541 tgcagaacca gtccacaaca ttatcattgc aagtgtttga tttgcccaag agaaatatct
    42601 ccaaattata ttaaaatcta taaatgtaag agcaacacca actgcgaata atggtaaagc
    42661 tattaaaaat ctatttttga ctgcatcttg attataattc attgcatctg ctattgtcag
    42721 tctagcactt ctaaatgctg tatctccaga agttatagga catgccacaa ctccaagtat
    42781 agctaaagct cctccaatag gccccattaa tccaacagat actgtattta ctactgttgc
    42841 tgctccacca tcattaaata tcacattaag ttgaggtatg ccatggaaat atgacatggc
    42901 tgctgctgcc caaactaaag ctattatacc ttctgcaacc attgacccat aaaatactgg
    42961 tcttgcctca ctctctttct caacacatct cgccataagt ggtgattgag ttgcatgaaa
    43021 acctgatatt gctccacatg ctattgttat aaataagtat gggaataaag gtgttccatt
    43081 tggattcata ttttgtaaat ttatatttgg tatgttatac ccctttatta ttaatcctcc
    43141 agctacacct actgccataa ttaataatgc tgctccaaat aaaggatata ttttaccaat
    43201 caatttatct attggtaaaa cagtagccat aatataataa agtattatca ctccaaccca
    43261 tatttgtgcg tttacacctg tcaatgtctt taataatcct gctggacctg ttacaaatac
    43321 aactccaacc aatactaaaa gaataacact aaatattctc attgctattt ttgcaccatt
    43381 tcctagataa aggcctacca actctgatgc agatgtacct ttgtttttca ttgatagata
    43441 tcctgaagca aaatcgtgta ctccaccagc aaagattgtt ccaaacacaa tccataaaaa
    43501 tgctgatggt ccaaataatg ccccttgtat agctccaaat ataggaccta accctgctat
    43561 atttagaaac tgaattaaaa agattctctt ccatttcatt ggcacataat ctactccatc
    43621 cctacaagct atagctggag tttgattttt gtcattgatt ccaaaaacct tttctacaaa
    43681 agtaccatag acaaaataac ctactataag tactactatt gaacctaaaa agcttaccat
    43741 aaattcatcc ccttagtttt tatataattg ctttataaat ttttatgagt ttaagaaaac
    43801 tatttccagt tcaaatagta atactttttt atgctaatat aaatattaat tacattaagt
    43861 gcatatttaa gtacatgaaa tgactttata tatgcattaa cagcctaaat tcttttactt
    43921 tgcttctact tacagttact tcatagtcac tattttttaa ttttaatatg tatgtattat
    43981 taaaccatgg tataatttct tttactttgg ttaagtttac gatataagac ctatgtgttc
    44041 taaaaaatgt tttatcattt ataagatttt cgacttctga tatgccttct tttaatataa
    44101 acttttcttt ctcagtatat ataaatgtct gcctttcatt agcttcacag taatatatat
    44161 catcaatatc tattacaact aatttatcac ctttccaaag gctaatttta tgtgttattt
    44221 cttctatctc ctgatttact gcttccttct tatatttgta taaattacta tttacattag
    44281 atagttcaat atcactcatc tcactttttt ctaatttatt cagcatagaa ataattctct
    44341 cttcagaata tggtttcaat atataatcaa atacatccaa agaaaaagca tctactgcat
    44401 aactttcata tgctgttata aaaacaattt taggtcttga tttaaactga tttagtgttt
    44461 ttgcaagtag cattccatca agatgaggta tatttatatc taaaaaaatt acatctattt
    44521 tattttcctg aataaagtct aacacctcta taccattggt aaattcactt actacctcta
    44581 ttccactttt attttcaata aaatatctca attcctttct tgctggaaat tcatcttcca
    44641 ctattatagc tctcatactt ctactccttt acataaaata ctatcaaagt cccattatct
    44701 attcttctta tattaagccc tcttccatac atcagtttaa gccttaaatg tacattataa
    44761 agcccaatct tattttctgg catattatct tgatatacat tatttataat ttcctcactt
    44821 atacctatac cattatcctc tattgatatt ctcacagtat tttctaatga atacggtaac
    44881 ttttttatgg atattttcac tacaccagct ctaccacttt ctaaaatacc atgtattatt
    44941 gcattttcca ctaatggttg tataatcaaa cttggaatct ttatatttac atcttctata
    45001 tcataagata cagttagtaa ttctccaaac ctagcttttt ctatctctac aaaagattta
    45061 acttgttcaa tctctttatt tatatcaatt aagttatcac tatattcaag attatatctt
    45121 agataagttg ataaatttat tattaactct ctagccttat ctggactaaa tcttataaat
    45181 gaagctattg tgtttagtga attaaacaaa aaatgcggat taatttgtct ttgaagtgct
    45241 tttatttctg ctttatttct cgcttctata tcttttttat ctttctcaat cccctctact
    45301 atagatataa caaatcctat tccaatctgc ccaactatta aaggtaaata tattccaccg
    45361 attatttgaa ttgctaaaga atgtggatat gatattaagt atataagtaa tatagtaaaa
    45421 ctttcagaaa tcatgcctac caatattcca tacattactc tatgttgttt tggtatcctc
    45481 ttatatagaa atcctgataa tacacctgct agtatacttg ataaaagaca tggaacagat
    45541 gttatccccc caatatccat aaaatatcta tgaatccctg aaaaaactcc tgctgtaata
    45601 cctaccattg gaccaaataa aatgccacct gatactatag atattattct agtgtttact
    45661 attgacccca tataatttat accactataa gttccaaata tggctaaaaa agtaaaaact
    45721 aatgctatac agaccaagtc attaaaacta tattcttcct tttgaaatat ctgcttaaat
    45781 atttttaact ttgttattag aagaaacaat actacaataa ggcttgtctt ttctattaat
    45841 gcgattaaaa ttgatgtttt cataatcccc ctttaaaaaa taaattttta cacactctaa
    45901 atttattatg gttgttataa attacatatt tgaagtaatc ctatcacaaa actttccaca
    45961 tttaatcttt taattaaata agaaatagtt gtacttctat taacaactaa tactagctag
    46021 cataagcttg taataacttg tagttattat taactttaca attctagtat ttaattttat
    46081 actttagaaa tctcttttct tagaaataat actttcgaat atcatataat acaatattat
    46141 gtagattctt actcatacaa catatttctt taaaaatttt atactattct ttgttcaaat
    46201 atctcatttg atttaattgt gttaaacaca cattatcatc tctctgttat atatttatta
    46261 tatagccgta tatcgataaa gtaaataaat cccatattta aaataatatg tttgacaata
    46321 aattattata atgtatattt accataataa tttgtcaacc ttgaaagtta cttctataat
    46381 tattgttaaa taattcttct aaaaaaaata cctataaatt ttattttctg aaatacatag
    46441 ttataactat ttttatcacg tataagaata aaaattccag aaaattttta ttatctaagt
    46501 taat
//
LOCUS       DAEPXW010000023        46161 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.023, whole genome shotgun sequence.
ACCESSION   DAEPXW010000023 DAEPXW010000000
VERSION     DAEPXW010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46161
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.023"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            103..1974
                     /locus_tag="KRM55_001234"
     CDS             103..1974
                     /locus_tag="KRM55_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HBH1593484.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRDLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYVGIGDEKVDLTANPVDSTGTNLDPSAEVFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNIVANGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKATELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNIERLAGDDRHTTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            2081..2788
                     /locus_tag="KRM55_001235"
     CDS             2081..2788
                     /locus_tag="KRM55_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH1593485.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEAKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDDLAINKIQYVHAP"
     gene            2821..4653
                     /locus_tag="KRM55_001236"
     CDS             2821..4653
                     /locus_tag="KRM55_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH1593486.1"
                     /translation="MKISKKIVSLLTMTFLTVTLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWKKSENAVLVNDNSIADALSATPFAKAKDAPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENINFERISGNSRYDTSLKLAEKLDREKSISKIVVV
                     NGDKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKGIEKSYVIGGTYSISN
                     SVERSLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTKNKNDLIDSLAVGV
                     LASKNGSPILLAGNKLDSSQKDVLNTKIIDKVTQIGGLGNEDVVDNIIDIQEKTKYTV
                     ETIEEFYVAMKKADANDVIIFETKKDDSINDSFEVKTTKAITVEFDGIFKKTITIDMP
                     NGDVNNFGEISDDIRINNIRKNTLINEGSIQGIDIYSKNGCKIENKSDGDIWLITIVS
                     EARGVYIVNDGDISKISNSCSDVIIKNSGKINLVTGTEEPAISGKKPITNDTEYDDER
                     AHGLSVKTEACSTPQKNYIIVTISSKPKNSNYAIYYRVVGDKPSAMYVGEKINPRDWY
                     SVSKSDDSFIEKAKNGSYIEVVEINSSNNRVSRWGRSSSTDDGL"
     gene            complement(4697..5098)
                     /locus_tag="KRM55_001237"
     CDS             complement(4697..5098)
                     /locus_tag="KRM55_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBH1593487.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIEIKFLFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDIIVKAFTNIVVIVLNYFFSKMIIFKNKK"
     gene            5326..7737
                     /locus_tag="KRM55_001238"
     CDS             5326..7737
                     /locus_tag="KRM55_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HBH1593488.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMDLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWDLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDLK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            8034..9611
                     /locus_tag="KRM55_001239"
     CDS             8034..9611
                     /locus_tag="KRM55_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBH1593489.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTTSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
     gene            9745..11052
                     /locus_tag="KRM55_001240"
     CDS             9745..11052
                     /locus_tag="KRM55_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBH1593490.1"
                     /translation="MGIGIKCNKKINKSIDKTRIKKNNLNSNSNSNSNSNSNSNSNSN
                     SNSNSNSNSNKISNNAVDSKLMNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRH
                     AVWHGVTLADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILFGFF
                     LNYLGNPDLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTFIIV
                     GYYILAKPYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGC
                     VLLKEDIGEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLS
                     IFYFICDIKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEW
                     TTYELITPWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            11306..13330
                     /locus_tag="KRM55_001241"
     CDS             11306..13330
                     /locus_tag="KRM55_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1593491.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            13550..14236
                     /locus_tag="KRM55_001242"
     CDS             13550..14236
                     /locus_tag="KRM55_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBH1593492.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            14331..15386
                     /locus_tag="KRM55_001243"
     CDS             14331..15386
                     /locus_tag="KRM55_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBH1593493.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            15501..17057
                     /gene="murJ"
                     /locus_tag="KRM55_001244"
     CDS             15501..17057
                     /gene="murJ"
                     /locus_tag="KRM55_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH1593494.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            17103..18809
                     /locus_tag="KRM55_001245"
     CDS             17103..18809
                     /locus_tag="KRM55_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH1593495.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            18831..19904
                     /locus_tag="KRM55_001246"
     CDS             18831..19904
                     /locus_tag="KRM55_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBH1593496.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            19916..20638
                     /locus_tag="KRM55_001247"
     CDS             19916..20638
                     /locus_tag="KRM55_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1593497.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVFTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            20654..21811
                     /locus_tag="KRM55_001248"
     CDS             20654..21811
                     /locus_tag="KRM55_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBH1593498.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            21814..22653
                     /locus_tag="KRM55_001249"
     CDS             21814..22653
                     /locus_tag="KRM55_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1593499.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            22668..23843
                     /locus_tag="KRM55_001250"
     CDS             22668..23843
                     /locus_tag="KRM55_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBH1593500.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            23872..24621
                     /locus_tag="KRM55_001251"
     CDS             23872..24621
                     /locus_tag="KRM55_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1593501.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            24643..25551
                     /locus_tag="KRM55_001252"
     CDS             24643..25551
                     /locus_tag="KRM55_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1593502.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            25599..26351
                     /locus_tag="KRM55_001253"
     CDS             25599..26351
                     /locus_tag="KRM55_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1593503.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            26305..27672
                     /locus_tag="KRM55_001254"
     CDS             26305..27672
                     /locus_tag="KRM55_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBH1593504.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            27678..28769
                     /locus_tag="KRM55_001255"
     CDS             27678..28769
                     /locus_tag="KRM55_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1593505.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            28853..30766
                     /locus_tag="KRM55_001256"
     CDS             28853..30766
                     /locus_tag="KRM55_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH1593506.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            30965..31672
                     /locus_tag="KRM55_001257"
     CDS             30965..31672
                     /locus_tag="KRM55_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1593507.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYAKRLITATRVLQ"
     gene            31974..34085
                     /locus_tag="KRM55_001258"
     CDS             31974..34085
                     /locus_tag="KRM55_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBH1593508.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(34283..35248)
                     /locus_tag="KRM55_001259"
     CDS             complement(34283..35248)
                     /locus_tag="KRM55_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH1593509.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(35533..36489)
                     /locus_tag="KRM55_001260"
     CDS             complement(35533..36489)
                     /locus_tag="KRM55_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH1593510.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            36857..37645
                     /locus_tag="KRM55_001261"
     CDS             36857..37645
                     /locus_tag="KRM55_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1593511.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(37768..38238)
                     /locus_tag="KRM55_001262"
     CDS             complement(37768..38238)
                     /locus_tag="KRM55_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBH1593512.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            38377..39021
                     /gene="uppS"
                     /locus_tag="KRM55_001263"
     CDS             38377..39021
                     /gene="uppS"
                     /locus_tag="KRM55_001263"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBH1593513.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            39064..39969
                     /locus_tag="KRM55_001264"
     CDS             39064..39969
                     /locus_tag="KRM55_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1593514.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            40284..41831
                     /locus_tag="KRM55_001265"
     CDS             40284..41831
                     /locus_tag="KRM55_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1593515.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            41834..42232
                     /locus_tag="KRM55_001266"
     CDS             41834..42232
                     /locus_tag="KRM55_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH1593516.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            42272..44005
                     /locus_tag="KRM55_001267"
     CDS             42272..44005
                     /locus_tag="KRM55_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBH1593517.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            44237..45448
                     /locus_tag="KRM55_001268"
     CDS             44237..45448
                     /locus_tag="KRM55_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH1593518.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            45641..45901
                     /locus_tag="KRM55_001269"
     CDS             45641..45901
                     /locus_tag="KRM55_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBH1593519.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
BASE COUNT        18646 a         4940 c         8146 g        14429 t
ORIGIN      
        1 attacaataa gtctcattta ttgaaataat atcaaatata tattataatt ggtaaataag
       61 gaaaaaataa taaaaatttg aattttttag ggggaaaata ccatgaataa aaaaaatctt
      121 tctgtaatta tggctgctgc aatgataagt acatcagtag ctccagtttt tgctgcagaa
      181 actacacagg taaaaaaaga aacaataact aagaaagaag ctacagaact agtttcgaaa
      241 gttagagatt taatgtctca aaagtataca ggaggttctc aagttgggca accaatatat
      301 gaaataaaag ttggtgagac tttatcaaaa ttaaaaataa taactaatat agatgaatta
      361 gagaaattag taaatgcttt gggagaaaat aaagaactta ttgtaactat aacagataaa
      421 gggcatataa caaatagtgc aaatgaagta gttgcagaag caactgaaaa atatgaaaat
      481 tcagcagacc tttccgctga agctaactct ataacagaaa aagctaaaac tgaaaccaat
      541 ggaatttata aagttgcaga tgtaaaagct tcatatgata gtgctaaaga taagttagtt
      601 ataactttaa gagataaaac agaaacagta acttctaaaa ctatatatgt aggtattggt
      661 gatgaaaaag ttgatttaac agcaaatcca gttgattcaa ctggaacaaa tttagaccct
      721 tctgcagaag tatttagagt aaataaaatc gataaactag gtgtagcagg agctaaaaat
      781 attgatgatg tccaattggc cgaaataact ataaaaaata gtgacctaaa tacagtttca
      841 ccacaagatt tatatgatgg atatagatta actgttaaag gtaatatagt agcaaatggt
      901 acatcaaagt caattagtga tatttcagca aaagattcag aaacaggaaa atataaattt
      961 actattaagt atactgatgc atctggaaaa gcaacagagc ttactgtaga aagtaccaat
     1021 gaaaaagatt taaaagatgc caaagctgca ttagaaggta attcaaaggt taaattgata
     1081 gctggagatg atagatatgc aactgcagtg gctatagcaa aacaaacaaa atatactgac
     1141 aatatagtta tagttaattc aaataaacta gttgatggat tagcagctac accacttgct
     1201 caatctaaaa aagcacctat attattagca tctgataatg aaataccaaa agtaacttta
     1261 gattatataa aagatataat taagaaaagt ccatcagcta aaatatatat agtaggtgga
     1321 gaatcagcag tatcaaatac agctaaaaag caattagaat cagtaactaa gaatattgaa
     1381 agactagctg gagatgatag acatacgact tctgtagcag tagcaaaagc tatgggttct
     1441 tttaaagatg catttgtagt aggtgcaaaa ggggaggctg atgctatgag tatagctgct
     1501 aaagctgctg aacttaaggc tcctataata gtaaatggct ggaatgatct ttcagcagac
     1561 gctatcaaat tgatggatgg aaaagagatt ggtatagttg gtggctctaa caatgtatct
     1621 agccaaattg aaaatcaact tgccgatatt gataaagata gaaaagttca aagagttgaa
     1681 ggagaaacaa gacacgatac taatgctaaa gttatagaaa catattatgg caaattagat
     1741 aaactatata tagcaaaaga tggatatgga aataatggta tgctagtaga tgcattagca
     1801 gcaggacctc tagcagcagg taaaggtcca atacttctag ctaaaactga tataacagac
     1861 tcacaaaaga atgcacttag taaaaaatta aatcttggtg cagaagtaac tcaaataggt
     1921 aatggagttg aattgacagt aatacaaaag atagctaaaa tactaggttg gtaacaattt
     1981 atactgtgga gaagattcct taattaatac aggaatcttt ttctataatt atgctattta
     2041 ttgtaaatta taacatttta taaagtagga ggacgtacta gtggtagatg caactttatt
     2101 ttttacacca catcaagatg atgaaacctt aagtatggga agtgctataa ttgaacatgt
     2161 tgaaaaaagt gatacacatg tcatattatg cacagatggt agtaaatcta taataagaaa
     2221 agttttggat gatggagggt catgttctta tcatattaaa gatgtccata agtactcttt
     2281 atcagaaagt gaattttcaa aagatagaga tgaagaattt aaggatagtt gtgaagcaat
     2341 gggtgtaaaa gaaagtaata tacatataga agataataga gcccatgatg gtgagctaag
     2401 taaggaaaag gcaagggaaa taatacttaa gtacttagaa gaatatccag atgcaaaagt
     2461 aaaaactgtt actccattta aagctagtgg aatacatgaa gaccatagag cattaggaga
     2521 agctgcatta gagttatata gagaaggcaa aataaaagat ttaagatttt atgtagaacc
     2581 atatgactat aaggatttta aaaaagttaa tccgaatgta gaagtatgga aggtattacc
     2641 tagtcaagag gcgaaattat taagtgcaat gaatgcatat aagaaatgga atcctgagag
     2701 tggacactat gctatagggt accattcagt aaaatctcat tttgatgatc tagctataaa
     2761 taaaatacag tatgtacatg ctccataaaa tattataaaa gaattaggag gtaagaatta
     2821 atgaaaatat caaaaaagat agtgtctttg ttaactatga catttttaac tgttacatta
     2881 tatggaaata catctaatgc atctacaaaa gatacattaa cgggttctgg aagatgggaa
     2941 acagcaataa aaataagtca agcaggatgg aaaaagtctg aaaacgctgt gttagtaaat
     3001 gataattcaa tagcagatgc tttatcagct actccatttg caaaggcaaa agatgcacca
     3061 atattattaa ctcaaagtaa taaattggat agtagaacaa aagcagaatt aaaaagactt
     3121 ggtgtgaaaa atgtatattt aataggtggt tcaattgcat taagttcaga gattgaaaag
     3181 cagttgaatg cagaaaatat aaattttgaa agaatatccg gaaatagtag atatgatact
     3241 tctttaaaat tagctgaaaa gctagatagg gaaaaatcta tatctaaaat agtagtagta
     3301 aatggagaca agggtcttgc tgatgcagtg agtgttggag ctatagctgc tcaagaaaac
     3361 atgccaataa tactttctga ttcagagaat ggaactgaag tagctgataa ttttatagat
     3421 agtaaaggta tagaaaaatc gtatgtaata ggtggtacat attctatttc taattctgta
     3481 gaaagaagtt tgccaaatgc aacaagaata gcaggtagta gtagaagtga aacaaatgca
     3541 aaaattatag aagaatttta caaagatact gatataaaaa atatttatgt aacaaaagat
     3601 ggtacaaaga ataagaatga tttaatagat tctttagcag tgggtgtatt agcttctaaa
     3661 aatggctctc caatactttt agcaggaaac aagctagata gttctcaaaa agatgtatta
     3721 aatactaaaa ttatagataa agttactcaa attggtggat tgggtaatga agatgttgta
     3781 gataatataa tagatataca agaaaaaaca aagtatactg ttgaaactat agaagaattt
     3841 tatgttgcga tgaaaaaagc tgatgctaat gatgttataa tatttgaaac taaaaaagat
     3901 gatagtataa atgattcttt tgaagtgaaa acaactaaag caataactgt agaatttgat
     3961 ggtatattta aaaagacaat aactatagat atgcctaatg gagatgtgaa taactttggt
     4021 gaaatatctg atgatataag aataaataat ataagaaaaa atactttaat taatgaagga
     4081 agtatacaag gtattgatat ttattctaaa aatggttgta aaatagaaaa taaaagcgat
     4141 ggagatattt ggcttataac aatagtatca gaagctagag gtgtgtatat agtgaatgat
     4201 ggagatatat caaaaatttc aaatagttgt tcagatgtca taataaaaaa ctcaggaaag
     4261 attaatttag tgactggtac tgaagaacct gcgattagtg gaaaaaaacc aataactaat
     4321 gatactgaat atgatgatga aagagcgcat ggattatctg ttaaaacaga ggcatgttcc
     4381 acacctcaaa aaaattatat aatagtaaca atatcatcta agcctaaaaa ttcaaattac
     4441 gctatttatt atagagtagt cggggataaa ccttcagcta tgtatgtagg ggaaaaaatt
     4501 aatcctagag attggtattc tgtatcaaaa tcagatgatt catttattga aaaagctaag
     4561 aatggatcat atatagaagt tgttgaaata aattcttcaa ataatagagt ctctagatgg
     4621 ggaagatcaa gctcaactga tgatggactt taaagtgtaa atatgatttt aaaagtagat
     4681 tactatttct agtagtctac tttttatttt taaaaattat cattttacta aaaaaataat
     4741 ttaaaactat aacaactata ttagtaaatg cttttacaat gatatcattt acaaaaagta
     4801 aatcaatcat tacatacata attaacattt caacgacacc agaaagtagc ctaaaactaa
     4861 caaaagacaa aaattcctta aataagaact ttatttcaat tcttttactt tcaaacacaa
     4921 aaaacttatt agtaacataa gcaaataaaa cagcaagtat ccatgccaaa gcatttgcaa
     4981 ccataaaatt aaataaaata actctagtaa aaaataaata cgaaactata tttacaagag
     5041 tagtaaatgc tccaaaaaat aaatataata ttgtctctct atgttttttt aaaatcaaat
     5101 ataatcctcc taagctaatt taatataaat atacttaaag atactaacaa acattagtat
     5161 agcacatcta ttaataaatc aatatatctt aaaatattat aaaaaataaa actataatat
     5221 tctataatta atatgtactc ataatccata ttttatcaaa ataaaatatg accttaattt
     5281 agaaatctga tataataaaa attaaataca tataaggggg taaacatgag aaagtataaa
     5341 tcaaaaaaat tgtcaaagct actagcattg ttgacagttt gctttttaat agtgtcaaca
     5401 atacctgtct cagcagaaaa ccataaaact ctagatggag tagaaactgc agagtattct
     5461 gaaagctatc ttcaatacct agaagatgtc aaaaatggag acacagcaaa atataatgga
     5521 gtaatacctt ttccacatga aatggaaggt acaacacttc gaaataaggg tagaagtagt
     5581 cttccatcag catataaatc aagtgtagca tacaacccaa tggatcttgg tcttactaca
     5641 ccagcaaaaa atcaaggaag tcttaataca tgctggtctt tttcaggtat gtcaacttta
     5701 gaagcatatc ttaaattaaa aggatatgga acgtatgact tatcagaaga acatttaaga
     5761 tggtgggcaa ctggtggaaa atatggatgg gacttagatg atatgtcagg tagttcaaat
     5821 gtaacagcca taggatatct gacagcatgg gcaggtccta agttagaaaa ggacatacca
     5881 tataatctta aatctgaggc acaaggcgca actaaacctt caaatatgga tactgcacct
     5941 actcaattta atgtaacaga tgttgttcgt cttaataaag ataaggaaac tgtaaagaat
     6001 gctataatgc aatatggttc agtgacatca ggttatgcac attattcaac atattttaat
     6061 aaagatgaaa cagcatataa ctgtacaaat aagagagctc cattaaatca cgctgtagcg
     6121 atagtaggat gggatgataa ttattcaaaa gataactttg catctgatgt aaaaccagaa
     6181 tcaaatggag catggttagt aaaaagtagt tggggagagt ttaattctat gaaaggattc
     6241 ttctggattt cttatgaaga taaaactcta ctaacagata cagataacta tgcaatgaaa
     6301 tcagtatcaa aaccagatag tgataaaaaa atgtaccaac ttgaatatgc tggtcttagc
     6361 aagataatgt caaataaagt aacagcagca aatgtatttg attttagcag agattctgaa
     6421 aaacttgact ctgttatgtt tgaaacagac tctgtaggag caaaatatga agtatattat
     6481 gcaccagtag taaatggagt tcctcaaaac aattcaatga caaaacttgc aagtggaaca
     6541 gtatcatatt ctggatacat aaatgtacct actaattctt acagcttacc aaaaggtaaa
     6601 ggagcaatag tagtagttat agacaacaca gcaaatccta atagagaaaa atcaacttta
     6661 gcatatgaaa ctgatataga tggatactat ctgtatgagg ctaaagcaaa cttaggtgaa
     6721 agctacatac ttcaaaacaa taagtttgag gatataaata catatagtga attttctcct
     6781 tgtaactttg ttataaaagc tataacaaaa acatcttctg gacaagctac ttcaggagaa
     6841 tctttaactg gagcagatag atatgaaaca gcagttaaag ttagtcaaaa aggatggact
     6901 tcttcacaaa atgcagtatt agtaaatgga gacgcaatag tagatgcttt aacagctaca
     6961 ccatttacag cagcaatcga ctctccaatt cttttaacag gaaaagataa cttagattta
     7021 aaaactaagg cagagttaca aagattagga actaaaaaag tttatctaat aggtggagaa
     7081 aattctttaa gcaagaatgt acaaactcaa cttagtaata tgggtatatc agtagaaaga
     7141 atttcaggta gtgatagata caagactagt atatctctag ctcaaaagtt aaatagtata
     7201 aaatctgttt cacaagttgc agtggcaaat ggtgtaaatg gacttgcaga tgcaataagt
     7261 gttggtgcag cagctgctga taacaatatg ccaataatac ttactaatga aaaaagtgag
     7321 ttgcaaggtg ctgatgagtt tttaaattca tcaaaaataa ctaagtctta tataattggt
     7381 ggaacagcta ctttatcatc aaatttagaa agtaagcttt caaatccaac aagacttgca
     7441 ggaagtaata gaaatgaaac taatgctaag ataatagata aattctaccc tagttcagat
     7501 ttgaaatatg cttttgttgt taaagatggt tcaaagagtc aaggagactt gatagatgga
     7561 ttagcagtag gagcattagg tgctaaaact gattcgccag tagttctagt tggaaataag
     7621 ttagatgaaa gtcaaaaaaa tgtacttaag tctaagaaaa tagaaactcc tattagagtt
     7681 ggtggaaatg gaaatgagag tgcttttaat gaactaaata ctcttttagg aaaatagtga
     7741 atggaaagat agtaaggata tacattttat tattaaaaaa tgttcaatag aagtttataa
     7801 atataaaata acaaaaaggg gtgtctcaaa atgaactttt tagttcatga ggcactcttt
     7861 tttgttgttt tatattttta tcatttaaat aatgaaaaat aggattgtct atatttttag
     7921 atagttttct tattattgat gaaaaatgta ataattttaa actgtaaaat agtgtaaagt
     7981 tattttataa tataaatata gtaagatttt aaacaaaata agggggaata ataatgaaag
     8041 caccaaaaac tattttaaca atactgacaa tagcgcttac tttaagtagc atttctataa
     8101 taccatcata tgcacttaca gaggaaaaat taataggtaa tggtagatat gaaactgctg
     8161 taaagataag tcaaaaggca tacagttcta gttctaatgt agtgttagtt aatgacaatt
     8221 cattagctga tgcactttca gccacaccat ttgcaaaggc taaaggagca ccaatacttt
     8281 tgacagaaag tgataagcta gatgatagga ctgaaaaaga gataaaacgt ctaggagcta
     8341 aagatattta tttgatagga ggtactgctg tacttaataa agatatagag aacaagttaa
     8401 aaggtaatgg acttaatgta gaaagaatta atggtaagga tagatatgaa acttcactga
     8461 ttttggctaa taagcttaag gatataaaag atattaagga agttgctgta gtaaatggtg
     8521 aaaaaggatt aagtgatgct gttagcgttg gagcaccagc agctcaaaat aagatgccta
     8581 taattttgtc tagccctaag gacggagtag aagcatttga taaatttata agagatgaga
     8641 aagttataaa agcatatgta attggaggta caacttcagt ttcaagagct gtagaaaaga
     8701 gtcttcctaa tgcagaaaga gtgagtggga aagatagaaa tgagactaat gctaaggtca
     8761 tagaaaagtt ttatactgat acaaatttaa gtaatttata tgtaactaag gatggtagta
     8821 aaaatgagaa tcaactaata gactcgttag ctgtcggagt attggctgca aaaaatgagt
     8881 ctcctgttgt tttggttggt aataaattaa acacaaaaca aagagatata cttagtacta
     8941 aaaaattaaa tactataaca caggtaggtg gaaatggaaa tgaagaagct tttgatgaaa
     9001 ttaaaagtct acaagaaaaa actgtgtttg aagcaaaaac tgttgaggaa ttaactgata
     9061 tgataaatat agcaagtcct aatgatatta taaactttaa accaaaagag aatactgtaa
     9121 atgaagcttt tagaatggta acaaataaac caataactgt gaatataaag ggtgattgtt
     9181 caaagactct tacagtagat atgcctaatg gtgaagtgaa taactatgct actttggtaa
     9241 atgttatagt tagaaatatt ggagaaggtg gatttaataa ccatgataca atcactatat
     9301 tgtcagttcg tgacaaaaat ggtagagtta tagaaaatac tagaaattca gatatagata
     9361 cgttgatgat attagcttct gctaatgata caaaattgat taatgatgga tatataggaa
     9421 aacttataga taattcatct aatagtgata taactaataa tggtactata gataaaaaag
     9481 ttaatcaggt tgaagattta gaggctaaag tagattcaat tgaaaaagct atagattcta
     9541 taagtcaaaa agtcaataaa atacaagata tactagataa gcttggattt ctaaagaaat
     9601 ttcttagcta agaatatgta tatttaagtg aagtgtgtgt tgtaattgtt ctaaatttat
     9661 gtagttaaac aggtttatat acaaatagat ttatagataa atatgtagtt tagtatatat
     9721 ttgaataagc tttggggagg taacatgggg attggaatta aatgtaacaa aaaaataaat
     9781 aaaagtattg acaaaactag aataaagaaa aataatctaa atagcaatag caatagcaat
     9841 agcaatagca atagcaatag caatagcaat agcaatagca atagcaatag caatagcaat
     9901 agcaataaaa tttcaaataa tgctgtagat tctaaactta tgaatagtag gattaaatca
     9961 atagatataa taagagggct atcaatagcc ctcatgatag tctgcaataa tcctgggact
    10021 tggatgagaa tgtatcctca attaagacat gctgtatggc atggtgtaac acttgcagat
    10081 tttgcatttc ctttttttgt tatatcttta ggtgttacaa ttccaatatc aataaatagt
    10141 aaactaaaaa ataataaatc cacactgagt ataatactta gtatattcaa gagaagtatc
    10201 ttattgatat tatttggatt tttcttaaat tacctaggaa atcctgattt agatactgta
    10261 agaatacttg gagtacttca acgtatggga ttagtctatt ttgtgactag tttagtatat
    10321 ttactactaa aaaaattaaa tgttggaagt actgctacaa taattacttt tctatgtata
    10381 tctacattta taatagttgg gtactacata ttagcaaaac cttatggatt tgagctagaa
    10441 ggttctcttg cacagttagt ggatttacat ttcttcaaag gacatttgta caagccggaa
    10501 tttgaaccag atggtttttt aactagtata gtagcaattt cttcaggtat gttgggatgc
    10561 actatgggat gtgtactttt aaaagaagac ataggagaat ataaaaaatt ctttaaaata
    10621 ctggttatga gcataatcct gctaataggt gcttttatct ttaatcagta ttttccattt
    10681 aataaaagat tatggtctag ctcatttgta cttttaatgg ctggcagtta tggtatatta
    10741 ctgtcaatat tttattttat atgcgacatc aaaaataaaa gtaaaatatt taccccaata
    10801 atagcacttg gaagtagccc tatttttaca tatatgtgcc ttgaaatatt gagtcatgtt
    10861 ttttggaatg ttccaaaact tacgaacaaa gtcgattatc caactacctt ggtagagtgg
    10921 actacatatg aacttataac accttgggca ggtacaactt gggattctct tatattttct
    10981 ttattgtatg tcctattctg ggttatagta atgtctataa tgtacaagaa aaaaatattt
    11041 attaaaattt agtgcaatat ttttagatga taaagtcttt gatttgttca aatatacgga
    11101 aactatcaaa tataatcaaa atttctcctc gataaaattt aaaaaccatg ccataaaaga
    11161 ttacaaaaag tttacaattt gtaatttttt gtgctataat gaaaaaagat ttacataata
    11221 ttgaatttat gtaatataaa acaagcttaa gatgtattaa aaaagattta aagagttaaa
    11281 gaaccaaaaa attagggggg atatgatgaa aaaaacaaca aaattattgg caacaggaat
    11341 gttgtctgta gcaatggtgg caccaaacgt agctttagcg gctgaaaata ctactgcaaa
    11401 tacagaatct aattcagata ttaatataaa tttacaaaga aaaagtgtag tgttaggaag
    11461 taaatctaat gcaagtgtaa aatttaaaga aaaattaaat gctgattcaa taacattaaa
    11521 ttttatgtgt tatgatatgc cacttgaagc tactttaaat tacaatgaaa agacagattc
    11581 atatgaaggt gtaataaact ataacaaaga cccagaatac ttaaatgtat gggaacttca
    11641 aagcataaaa ataaatggta aagatgaaca gaaagtttta aacaaagaag acttagagtc
    11701 tatgggatta aatcttaagg attatgatgt tacacaagag tttataataa gtgatgcaaa
    11761 ttcaacaaaa gcagtaaatg aatatatgag aaaaacttct gcaccagtaa aaaaacttgc
    11821 tggagctact agatttgaaa ctgctgttga gataagtaaa cagggttgga aagatgggtc
    11881 tagtaaggtt gtaatagtta atggagaatt agcagcagat ggaattacag ctactccact
    11941 tgcatctaca tatgacgcac caatattact tgcaaataaa gatgatatac cagaaagtac
    12001 aaaagcagag ttaaaacgtc taaatccaag tgatgtaata attataggtg atgatggttc
    12061 agtttcacaa aaggcagtgt ctcaaattaa atctgctgta aatgtaaatg tgactcgtat
    12121 tggtggagtt gatagacatg aaacatcttt acttatagca aaagaaatag ataagtatca
    12181 tgatgttaat aaaatataca tagcaaatgg atatgctggt gaatatgatg ctcttaatat
    12241 ttcatcaaaa gctggtgaag accaacaacc tataatatta gctaataaag attctgtacc
    12301 acaaggtaca tataattggt tatcttcaca aggtttagaa gaagcttatt acataggtgg
    12361 tagtcaaagt ttatcatcaa aaattataga ccaaatatct aaaatagcaa aaaatggtac
    12421 ttcaaaaaat agagtttctg gagcagatag acatgaaaca aatgcaaatg taattaagac
    12481 tttctatcca gataaagagt tgagtgcaat gttagttgca aaatctgaca taatagttga
    12541 ttcaataaca gcaggacctt tagcagctaa attaaaagct ccaatactta taactccaaa
    12601 aacttatgtt tctgcatacc atagtacaaa cttatcagaa aaaacagcag aaacagtata
    12661 tcaaattggt gatggaatga aagatagtgt tataaattct atagcatcta gtttatcaaa
    12721 acacaatgca ccaacagaac cagataattc aggttcagca gcaggaaaaa ctgtagtgat
    12781 agacccaggt catgggggtt ctgattcagg ggcaacaagt ggattaaatg gtggagcaca
    12841 agaaaagaaa tatactctta atacagcatt agcaactact gaatatttac gttcaaaagg
    12901 tataaatgtt gttatgacta gagatacaga taaaacaatg gctttaggag aaagaacagc
    12961 attatcaaat actataaagc cagatttatt tacaagtata cattacaatg cgtctaatgg
    13021 agctggtaat ggtgtggaaa tttattacaa agtaaaagat aaaaatggtg gaacaactaa
    13081 gactgcagca tcaaatatct taaaaagaat actagaaaaa tttaacatga aaaatagagg
    13141 aatcaagaca agaacacttg ataatggaaa agattaccta tatgtgttaa gaaataacaa
    13201 ttatccagca atacttgttg aatgtgcatt tattgacaat aagagcgata tggataagtt
    13261 aaatactgca gaaaaagtaa aaacaatggg aactcaaatt ggaataggaa tagaagatac
    13321 agtaaaataa aatagaaaat attaaagcaa aacatatcat ctcctgttat aatgtaaaat
    13381 ataacaagag atgatatatt tttgtaaaga atcaaattgt ttacaatgat gtttcttgta
    13441 ttgataatct gctcattatt gagtataata tagaaataag tcaaaaataa gatagaaata
    13501 agttgaaatt aagaattaaa aaaattttta ttccaatatg gaggtaacta tgtctggata
    13561 tactaatgat gagtgtgaaa tacctaaaat taaaagctat ccaggggcag ataaagaaat
    13621 tgcaagtgag attgactata gcatagtaaa aggaacagtt ttattcgact tgtaccaaag
    13681 aattatggat ttagttttat ctataatagg acttgtgata ggtttacctt taatagcaat
    13741 atttggaatt cttattaaaa tagaggacaa aggaccaata acttataagc aagaaagact
    13801 aggaaaatgc gggagaagat tctatatata taaattgaga tctatgagaa cagacgcaga
    13861 aaaatttggc gcacaatggg ctgaaaaaga tgatcctaga ataactaagg ttggaaagtt
    13921 tattaggaaa actagaattg atgagattcc acagctgttt aatatattaa agggggacat
    13981 gggcttaata ggtcctagac cagagagacc gaactttact gttcaattta atgaggaaat
    14041 acctggattt atcaacaggc tcgctataaa acctgggctt acaggttggg cacaagtaaa
    14101 tggtggatac gaaatcactc ctgaagaaaa acttaaagaa gatatttact atataaaaaa
    14161 taggagtata ttacttgact ttaagatact ctttaaaact gttaaagtag tattgacagg
    14221 agacggagct agataatttt aaaatattag attactaatc aatgaaaaag ctctttaaaa
    14281 agagcttttt tattgtcaaa aaatacaaaa aagaaaagga atgagaactt atgattaaaa
    14341 aaatttctac tatattatcg ttagttttgt taatctctat ttctagtacg ataggagtat
    14401 ttgcagatgc aaatcccaaa agagagttga tagaagggag tataccagag atttcgacag
    14461 aattaaataa aagagcattt aaggattcta aagaagtaat tcttgtaaat gaagagtcaa
    14521 ttgtagatag tataagtgca acacctttag catatgcaaa aaatgctcca atagttgtaa
    14581 ctaagagtaa aaatcttggt agagtaacaa gaaattatct aaaagaacta ggtccagaga
    14641 aggttacgat agtaggtggt ttaaaggcag tatctaaaga tgctgaacgt aatatagaaa
    14701 aaatgggaat gaaagtagaa agaataagag ggaaagacag atatgataca tctttaaaga
    14761 tagctagaga aatgtataga acagtaggat ttgatgaagc atttttactt agctcaacaa
    14821 caggattaga gaacgccata tctgtatatt cttatgccgc taaaagtgga atgccaataa
    14881 tatgggctaa agatgaaggg tttgaggaac aaattgattt cttaaaaggc aaaaatctta
    14941 aaaaaatata tgcattaggt gattcaaaag agtttattgc agagattgat tctaacttaa
    15001 aaaatataga aggaataaag caaataaata agtcaagtac aaatgttgat ttaataaaga
    15061 agttttatga tgaaaaagat ataaagaaaa tctatactgc tagattagac tttggtagta
    15121 gatctgatgt aaacgaatat atttctttgg gagtagtatc agcaaaagaa aatatgccaa
    15181 tactgatttg tagtgataac ttaagtcgtg cacaagataa attcttgaaa gatagcaata
    15241 taaatgatgt agttgaagtt gggtatacag taggtgatta tagtctattt aagagcatat
    15301 ttaatctaac attcttatct tgtatagtat taatactatt attactattg attacattta
    15361 gggcacttag atatgagtcg aaatagtttt tgatttataa ggaagctttt cataggttaa
    15421 atttacttaa ttagaataat gtttataagc agttttaaaa gttctacttt tagagtttaa
    15481 attagataag gagaaagaag atgtcaaaaa cagctaaagc agcattgtgg attatggcag
    15541 ccactatgtt ttcaaaagta ttaggtttcc ttagagaact tgtacttgca aatttctatg
    15601 gaacaggtat gtatgcagac gtatttgtat taacattaaa tatacctggt ttaatcatag
    15661 cagtcatagg ctctgcagtt gctacaactt atatacctat gtactttgag acaaagaaaa
    15721 gactcggaga tgaaggtgcc ttaaaattta ctaataatgt tttaaatata tgctatataa
    15781 tggctatagt aatagctatt attgggcttt tatttacaga gcaatttgtt acagtatttg
    15841 cagcaggatt tagaaacgac cctgctaagt tccaagcagc aatattattt actaaaataa
    15901 tgatttcagg agttttattc ctgagtggaa gtaagatatt tagttcattt ttacaggtga
    15961 atgacagttt tgtaattcct gggcttatag gaatcccata taatattata ataatagcag
    16021 caatagcact aagtgcaggt aaaaatgtat ggatactgcc agcaggagca ttattggcta
    16081 tggcgagtca gctattgttt caactgccat ttgcgtttaa gaagtcctac aagtataagc
    16141 catatataaa tttaaaggat gagtctataa aagagttagt caacctagta ttgcctatgt
    16201 tggtaggagt agctgttgga cagttaaata tatttgttga ccgattattg gcaaccactt
    16261 tgggtgatgg aaagttgtct gctcttaact atgcaaatag gctaaatgag tttgttatgg
    16321 cattatttgt tacatctata ataacagtta tatatcctaa actagcaaaa atgtctggta
    16381 aagataataa agaaggattt ataagcacta ttgtaaaatc ttcaaattgt attatattgg
    16441 tggtgcttcc tatatctata ggagctatta tattagcaga gcctcttgtt agaatattat
    16501 tccaaagggg taaatttgat gcgttatcaa cagaccttac atctatagcg cttagattat
    16561 attcactagg tttattggct tgtggagtaa gagatgtctt atatagggca ttttactctc
    16621 tttcagatac aaaaacgcca atgataaatg gaagtatagc tttaataata aatatagttc
    16681 ttaatttaat attgataaga ccattgggtc atgcaggtat tgctatatca actagtacat
    16741 caaacataat tacagttata ttattattta tatctcttaa aaagaaaaat ggatattttg
    16801 gaggggataa aattataaag actggtctaa aaagtttggt agcatctggt gtgatggcag
    16861 tagctacttt attgatatat aataatctat atgcatttat gggttcagga acaattaaag
    16921 aaattatatc agttggagct ggagtattag gtggagcttc tgtatatact gtattgatag
    16981 ttttatttaa ggtagaagag atggatttag cttttgaatt tttaagaaaa ggaaaacaaa
    17041 aactacttag aagatagata attaccttga aattttaaat tagagtcaga aaggatgaaa
    17101 atatggatta taagaataat tatgagatgt ggttaaattc tccttatttt gatgaacaaa
    17161 cgaaaaatga gctattaagt ataaaagatg atgaaaaaga aatacaagat agattttata
    17221 aaaatttaga gtttggaaca ggtggtttaa gaggtataat aggagcggga actaatagaa
    17281 tcaatattta tactgttaga cgtgcgacac tgggcgtttt aaattatatc atgaaaactc
    17341 aaggagaaga aggtaagcaa aagggaatag ttatagcaca tgatagtaga tacatgtcta
    17401 gggagttttg tatagaagta gcaaagactt taagtgctta tggtgtaaag gcttatattt
    17461 ttgaagaatt aaagcctaca ccagaacttt cttttgctgt tagatattta aagtgtgcta
    17521 tgggaatagt aataacagca agtcataatc ctaaagaata caatggatat aaagtatatg
    17581 actcagatgg tggtcaaatc tgtatagata tggcaaatga tataatagca gaagttaata
    17641 agattgatga ttacagtact attaaaagta tagattttga agaagcttta tctaaaaatt
    17701 taataactat attagataat gaagtagatg atgagtttat aaaagctgtt aagaaacaag
    17761 ttttaagaca aaatataata gatgaatacg ggaaaaaatt aaaaataata tatacaccta
    17821 ttcatggtac aggaaataag ccagtaagaa aagtcttaaa tgaatgtggt tttgaaaatg
    17881 taatggtagt taaggagcaa gaattgccag attctaattt ttcaacagta aagtatccta
    17941 atcctgaaga aaagtcagtg tttaatatag ctattgaaat ggcaaagaat aatggcactg
    18001 atttgataat aggaacagac cctgattgtg atagagtagg tatcgttgta aaagattcaa
    18061 gtggtgaata tgtagtctta aatggaaatc aagtcggttc acttttagtt agatatatat
    18121 tagagagttt agttgaagaa aataaacttc ctaaaaacaa tcctacaata ataaaaacta
    18181 tagttacatc agaactaggt gcaaaaatag caaaagctta taatgtagat tgtttaaata
    18241 ctttaacagg atttaaattt ataggagaaa aaataaaagc gtttgaagaa agcaatgata
    18301 gaagttttat aatgggatat gaggaaagct atggttactt aattggaact catgctagag
    18361 ataaagatgg tgttgtatct tcacttatga tatgtgaaat ggcagcatac tattcttcaa
    18421 aaggtatgaa cttgtatgaa gctttgatag atacatataa taaatttgga tactacaaag
    18481 aggacttaaa gtcagtaact ttaaaaggca tagatggaat aaaaaaaata aaagagatga
    18541 tgctttactt tagaagtgtt aaaatagata atgtggctga tgtaaaagta gataaaattt
    18601 tagactataa agatggtgtt gatgatttac ctaagtcaga tgtacttaaa tttttacttg
    18661 aagatggttc ttggatagct ataagacctt caggtacaga acctaaaatt aaattttact
    18721 ttggagcaaa ttcagacaat caagaagatg tagaatttaa gttgaacaat ttaatatctt
    18781 atatattaaa tgtagtggat tctatataaa aagctaaggg gagataaata atgaaagtat
    18841 acaatgtcat aatggctgga ggaggaggaa ctcgtttctg gccacttagt agacaagaag
    18901 tacctaaaca gcttataaat ttaagtggag aagatgcttt aataaacgaa actataaaca
    18961 gaatagattc tctagcaaaa aaagatgatt tatttatagt aaccaatgag aagcaattgg
    19021 aagctttaaa ggatatagta aaagataaat gtttggatag taatatattg ccagagccat
    19081 gtgccagaaa tacagcagca gctataggct ttgcagcatt taacataatg aaaaaatatg
    19141 gtgatggtgt tatgtgtgta tatccagctg accattatat aaaagatgaa aaagaattta
    19201 aatctatttt ggaaaaagct atctatatag cagaaaataa tgataaacta gtaactattg
    19261 ggataactcc tacatttcca tcaacaggat atggatacat aaattttaat agagaaaata
    19321 ctatagaaga tgttgcatat gaggtagtgg agtttgtaga aaaaccaaac tatgaaattg
    19381 ctaaagaata tgtaaactct aaaaagtatg tatggaatag tggaatgttc gtatggaagg
    19441 tatctaaaat actagaagat tttaagagat acttgccaaa agtatatgaa aaattagaag
    19501 atataagtaa atacttagga acaaaagaag aaatggaaaa aataaaagaa atatacccaa
    19561 ctatacaatc aatctctata gattatggta ttatggaaag aagtaatgat gttatagtag
    19621 ttcctggtga ttttggatgg aatgatgttg gttcttggga ttctctaggt gcaatatatc
    19681 caactgatga tgaaggtaat atcaaaagag gtgaaaatat tactatagat actaaaaatt
    19741 caattatata ttcagatgac aaattaatat cgacaatagg tattagtgat ttgatagtag
    19801 tatctacaaa tgatgcagtt atggtttgta gaaaagataa agctcaagat gtcaaaaaaa
    19861 tagtagagca gttaaaagaa gaagatagac aagaatatat gtaggaggtg ttcatttgat
    19921 tcctaaaaaa atacattatg tatggtttgg tggtccaaaa ggaaatatag aaaatatatg
    19981 tataaattct tggaaagaaa agcttccaga atatgagata gtagagtgga atgaaaaaaa
    20041 ctttgatata gagaaagaaa taaaaggaaa taagtttttg gaagaatgtt ataaaagaaa
    20101 actttgggca ttcatatctg attatacaag aataaaagta ctctatgaac aaggtggagt
    20161 ttatatggat acagatatgc aaatattaaa ggatataact cctcttttag aaaataatag
    20221 gctaatctgt gggtatgaag atgatagaga gtatataaat ggtgctataa taggtgtaga
    20281 aaaaggacat ccttttttaa aagacttatt ggagtattat gaaaaagaag tatttacttc
    20341 ttcattgttt acaataccaa agataatgac tcatcttatg gaaaagaatt ataagaagat
    20401 tgacccaaat aattatgaag aaggaatacg tgtttacgac aaagaatatt tttatccttt
    20461 tggatttaaa gaagacttta caccagaatg tataacagaa aacacttttg ggatacattg
    20521 gtggggaaaa agttgggcta aaaagagaaa ttatttctta gaaagcaaac acttaacagg
    20581 tgtaaataag atatggaagt gttgtaaaat atttgcaagt aatactttac gaagctaaaa
    20641 gggagaaagt aaaatgaaga ctttaaatga tgatagaaat attatgatta gaaaatatct
    20701 ttatatattt gttttgttta tcatattact tagaaagtat atgatatcat ttattgaccc
    20761 aaatatggat atagggatga ttaaatcagc gttattttat tcttcaatag gaatactaat
    20821 gctacttttt ttatttgata agagaaaaag tataacagaa atggtactag ttggagtttg
    20881 tgtcttactt tatttattaa atagggaagg agctatatta ttaatcgttt tattagctgt
    20941 atcagctaag caaatagatg ataaatttat agttaaaaat tatttaataa tatcggcatg
    21001 ttttttaatg gtagctatat tattatttaa tctatttcct tcattaatat ttaatcagga
    21061 agtccactat agatatatag aaaaaataga tatgcttgtt acaagaatgg attttggact
    21121 tggtaatcca aatagtgtat tttatcatat ggttactata tatgcagcat atatattctt
    21181 aagatataaa gattataata aatgggatag aataatttta tttggttctg cattttttgt
    21241 ttatcaaacc acatatagta gaactggatt tttcactata ttagcaggat taatatttgt
    21301 agaaataata agatggatag atataaaaaa aataaaagga ctaccaatgc tcctaaagac
    21361 attaccaata atacttactt tatttagtgt aattattggt acagtatttg ataaaagcac
    21421 tttattaaat aggttattag caagtagacc taagttctgg catgtatact tggctgaaaa
    21481 ggggaacttt ctaaaacctt ttggaaattc atatagtcct gctataaaag caactaatcc
    21541 attagatagt tcttatgtat atataattag tgtactagga gtagttgctt gtatattatt
    21601 tatgtatttg atgtataaag gaatagaaag ctttatagaa aaagataaaa aagcatattt
    21661 agtagcttta tttatatttt tactatactc ttttgcagaa aatttattat tagaagcttc
    21721 atttagtttt gcagtagtat tactaataaa agaagtgata ttaaatgata aaagggaaat
    21781 agatttgtgg aagatgaaaa gtaggaggta gtaatgttaa tatcattaat aatgccaaca
    21841 ttaaatagat atgatgatat atacttactt atggacagct tagaaaatca aacttacaaa
    21901 aactttgaac ttatagtagt agaccaaaat gataatagca aagttaaaga aatagttgat
    21961 aaatacattg ataagttaga tataaagtat ataaaaagct ctaaaaaagg attgagttat
    22021 aacagaaatg taggcataga caatgctgta gggcaaatta taggtttccc tgatgatgat
    22081 tgtgtctacg aaaatgatac attagaaaaa gttataaatt tctttaataa aaataaagat
    22141 tataaaatat acagttgcaa aactatggat tcaaataaag ttgatgcatt taagaaaatg
    22201 tatgatggaa cttgtgatat cacaagttcc aacgttttgg atactataac atccataact
    22261 ttttttattg attttgaagg taaagactat acaagatttg atgagaaatt gggtgttggt
    22321 ggagagtttg gtgctggtga agagatagat tatgttttaa acttattgag tttaggtttt
    22381 aaaggaaaat actttggaaa tgatataatt taccatcctg caaaaaaaca ttctaaatct
    22441 aaagaaaagt atcaaaaaga ttataactat ggaagaggct ttggagcgct ttgcaaaaag
    22501 gaaatagtct atagaaaaaa ttataagttt gcaaaagtta tggtatcaaa acttgtaaga
    22561 aatataggag gtcttatatt gagttccaat agagattatc atagtgccac tataaaagga
    22621 agaattaatg gatttagaca gtacaagtta taatgaggat ggtgtttatg gacaaggtta
    22681 aatttttaat aaatatgctt ttggcttttt ttatatatcc atttaataag cataagttta
    22741 atggtagaga tatctggctt ataggtggac attcagggga tatatacaat gataattcaa
    22801 agttttttta tgagtatatg ctaaaagaac ataatgatgt agaaacttat tgggtagtaa
    22861 ataaagacag taaagtattt gataaaattc caggcaaaaa attaataaga ggaagtgtag
    22921 aaaactatct gtattattac aattcaaaag ctatagtatt ttcacatgca ccatcagcag
    22981 atatagcacc atacaatttt gctgtacctg ttcttaatta ttttcataaa aaaacgataa
    23041 aagtgttttt aaatcatggg actataagtt ttaaaaaaag aaaacctatg aacaaaaagt
    23101 tcaaaaatat tatagataac ctatataaaa gctataatat agttacagca agttctgaat
    23161 ttgaaagaaa tgttatggta aatgattggg gaatgttaga tgactcagtt tatataattg
    23221 gaaatgcaag atatgacaat ttaccaacaa atgaagttgc acaaactcga gatatattat
    23281 atactcctac atggagagat tggataaaat ttagttcagg aaaatttacg gatacagatt
    23341 attttaaaaa tataatgaat tttttaaatg atgacaaatt aaataaaata ttagatgaga
    23401 aagatataaa tgtaaaaatt tatatgcatc atcttatgca tgagtttata gatgatataa
    23461 aagaaaatat aacaggaaaa cgaattgtgt ttttagataa aggggtaact ctagcaaatg
    23521 aaatcagaaa atcagctgca aatataactg attattcaag tgtagccata gactttttgt
    23581 atatgaatag acctatcttg ttttaccaat tcgatttgga tgaatatatg gaaaaagttg
    23641 attcatatat agatttaaaa agtgaaatgt ttgggtcttt ggcttataat aatgatgaag
    23701 ccgtgaataa acttattgat attattgaaa ataattttga ggttatggat aaccaaaaaa
    23761 atgaaagaaa taagtttttc agatataatg ataataagaa ctgcaagagg atatatgatt
    23821 gtgtattaag taaaattaaa taaatatttt ataaatgatg aggaaggtaa tatgaagaag
    23881 aatttagtat ctataattac tcccatgtat aattctgaaa aatttattga agcaaccata
    23941 aaatcagtat taaaccaaac ttatcaagaa tgggaaatgt taattattga tgattgctca
    24001 acagataata gtcctaatat agtcaaatct tatatgcaac aggatagtag aataaaatgt
    24061 ataaagactg agactaataa gggtgtctct aatgctagaa atttagcact aagtaaggca
    24121 acaggacaat ttatagcttt tttagatagt gatgaccaat ggaatagtag taagttagaa
    24181 aaacaagtaa attttatgtt agaaaatgac tatgtaattt catttacttc atatgaactg
    24241 atggatgaaa atgataaaaa attaaacaaa gtaataaaag ttccacctaa tgtagattat
    24301 agaagattat taaaaggaaa tatcttagga tgtcttactg ttgtgattga taagtctaaa
    24361 ttggattttg aaataagaat gagtggtgta agacatgaag attatgtttt atggttatcg
    24421 atattgaaaa aagggcatat tgctcatgga ataaatgaag ttctagcatt atatagaaaa
    24481 tctagcaatt ccctaagtgg taataaaata aaagctgcta tgtggacttg gaatatatat
    24541 agaaatatag aaaaaatacc tttatacaaa gctatatact actttattaa ttatggaata
    24601 aacggaatca aaaaaagtta gacagagagg aagatttaat taatgtataa atataaattt
    24661 actgtattta ctccgacgta taacagagct catttacttg aaaatttgta caatgattta
    24721 aaagctcaaa cttatgattt caatgatttt gaatggttga ttgttgatga tggaagtagc
    24781 gacagtacta aagagttagt tgaaaaattt atatcagaaa ataaattaaa tataagatat
    24841 atatacaaag aaaatggagg aaaacatact gcaataaatc taggtgtaaa aaatgcagat
    24901 ggagagctat ttttcattgt agatagtgat gatggtttaa ttaaagattc tcttgaaatt
    24961 gctaatgatg agtgggattc tttagagaat aaagaaggat ttagtggagt tgttggactt
    25021 tgtgtatatc caagtggaga tttgataggg acagaaatgc ctgaagataa gaaaatatgt
    25081 cactttgcag acctatattt taagtatggc gttaagggag ataaaagcat agtatttgta
    25141 actgatgagc ttataaaatt tccttttcca gaaagaaaag aagtgagatt tttaccagaa
    25201 agtgtagtat ggaatgaaat gtctaaatac tataaagtta tatgtgtaaa taaacctatg
    25261 ataataagag attatttgga tgatggtttg actaagaata tattaagtaa aaatgcatta
    25321 agaggtagag cattagagtt tttatattta ataaatcaaa atacatatcc attaagtaga
    25381 tatccatata tgtggataaa aaattacata aatttagcca gatactcatt gttgtctgat
    25441 agtcattatt ttggtgaatt aagaaaagta tctgataaat tgttgtattt agcattattc
    25501 ccattaggat attacaaata tattggacaa agaaaattag tatctaagta aacttgttgg
    25561 tatagtactg ctagttgcta tataaggaga gtaaaaatat gaatgagcct ttagtatcga
    25621 taattactcc tgtttataat tcagaagagt ttttatcaga gacgataaag tcaatccaaa
    25681 atcaaactta taaaaattgg cagcttttat tagtggatga ttgttctaag gacaattcaa
    25741 gtgaaattat aaaaagtttt cgaaaagaag atgctagaat aaaatatata aagcttgaaa
    25801 aaaattctgg agctgcagta tctagaaatg ttggtattaa gaatgcggaa ggtcgattta
    25861 ttgcatttgt agatagtgat gatttatggg atagtagaaa attagagatt cagatagaat
    25921 atatgttaaa agaaaatgta ggtttttctt ttacatctta tagatatatg agacaagatg
    25981 ggtcaaaaac gaataaggtt gcaagagctc ctaagaaaat tgactatgaa ggattactta
    26041 gaaatactat aataggatgt tctacagtgg tcattgataa ggagattgta ggagagttca
    26101 gcatgccttt ggtaagaaga ggacaagata ctgcaacctg gttacagtta cttaaaaagg
    26161 aaaaatatgc atatgggatt caagaagatt tagtgaatta cagattagtt ggaaattcta
    26221 tatcaagtaa caagataaaa gcattaaaac gaacttggaa tacttataga aatgttgaaa
    26281 atttaagttt accaaaaagt ctatatgtat tttgtttcta tgtttttaat gccattaaaa
    26341 aaagagtata agttttatat acttggaggt aaaaaaatga aaatagctat agctgggacg
    26401 ggatatgtag gtttggttac aggtgtttgt ctagcagagg taggcaatga aaatgtagtc
    26461 tgtgttgatg tagatgaaca aaaagttaaa tcaatgaaac ttggaatagc acctatatat
    26521 gaagaaggcc tagaagaact tatggttaaa aattacaaca gaggaagaat agattacact
    26581 acagactata aaaaagctta tgaagatgta gatgtaatat taatagctgt aggtacacct
    26641 gagagaagtg atggctcagc caacctagat tatataaagg cagttgcaaa gcaaatagct
    26701 gaaactgtga caaaagatac tctagtagta ataaaatcta cagttccaat tggtacaaat
    26761 gaagagatag aagattatat aaatagaaac ctaaaaaatg atgtaaaagt agagcttgca
    26821 tctaatccag agtttttatc acaaggaaca gcagtaaaag atactctaca tgcttcaaga
    26881 atcgttatag gtgtagaaag tgaatgggct agagaaatat tagaggaaat ctataagcct
    26941 tttaatcaac ctataatagt tacaaataga aatagtgctg agatgataaa atacgcatca
    27001 aataacttct tagctcttaa aatatcattt atgaatgata ttgcaaatct ttgtgaaata
    27061 gcaggagcta acatagaaga tgtagcttta ggaatgagtt atgatgatag aataggaagt
    27121 aagtttttaa aggcgggaat aggatatggt ggttcttgct ttccaaaaga cacaaaagct
    27181 cttcactggt tatctgaaca taatggttat gaattaaaaa cagtaaaagc tgcaatagaa
    27241 gttaatgaaa gtcaaaaact taaattagtt agaaaggcat ctaagttagt agagagcttt
    27301 caagatatga aggttgctgt tttaggtttg acttttaaac cagatactga tgatataaga
    27361 gaagcaccat ctataccaaa tataaaatat ttgctcgaaa gaggggcaag agttactgta
    27421 tacgacccaa ttggtgtaaa taatactaag aaaatatttg gtgactctat actttatgct
    27481 gattctgtag atgatgcgat agaagatgca gagatatgtt ttataatgac agaatggaaa
    27541 gatgtattaa attatgatat acataagtat aaggaaaaga tgaaaaatcc tttagtcctt
    27601 gatggaagaa attgttataa aattaaagat atggaagagt taggaattga gtattattcg
    27661 ataggaaggt aaatattatg aagactgttt gttatttagc tgatgggtca aatcctcata
    27721 ctttaaaatg gtgtagtttt tttaaaaata aaggatatga cattcatgta atttctttaa
    27781 atggaggtca catggaagga ataaaaattt ataattttgg ttctaatgta gaagaactaa
    27841 aaaatgaaaa tatttctaaa aaaacgggat acttaggttc aataaagcag ataaagaagc
    27901 tagtaaatga aataaagcca gatatattgc atgcacagta tgcaagtagt tatggattta
    27961 taggaagtct acttgggtat catccatata ttatttctgt ttggggtact gatatttatg
    28021 atttccctaa taatggtttt atacaaaaac aaattataaa gcataacttt agaaaagcag
    28081 actatatctt ttcaaatagt agagatatgg ctaaagaggc taataaatat acagctaaac
    28141 atgtagatgt aacctttttt ggagtagata tggataggtt taagcctatg gaagtagaaa
    28201 aagaagacgc ttttgtaata ggaattataa agagtttaga aaaaaaatat ggaatagaat
    28261 atttaataca agcatttaag atgcttaaag atgaatataa agataagaaa ataattctta
    28321 aaataggtgg ctctggaagt cagatggaca acctaataaa tttagctaaa gaattgggta
    28381 tagaaaatga tgttcagttt ttaggaagaa tatctccaga aaatgtaagc aagactttta
    28441 attcttttga tgtaactgta tttccttctt taagagaggg atttggagtg gcagctatag
    28501 aatcagaagc atgtgaagta cctgttatag ttacaaatgt aggaggacat ccagaatctg
    28561 tatgggaaaa tgaaactggc ttaattgtag aaccaaaaca accagaagaa ataaaaaatg
    28621 ctataataaa actaatggaa aatgatgaac ttagacttaa tatgggtaag aaagggcgtc
    28681 aatttgttag agaaaattat gaggttaatt taaactttaa tgatatagaa aaaatttatg
    28741 attctatatt tgataaatat aaaaaataaa atgaaaaaat acagcaaaag atagatgttg
    28801 ttggctatgc ttaggtgcgt agcttttgct gtttaaagga gggcttctag ttatgcgaga
    28861 aagtatagat ttagagaaag aaagcttttt taataggctt tttaaaaaat ataaatttag
    28921 acatttaaca ctattaattc tagatatttg tagcgtacta gtagcgtttc gaatgtcttt
    28981 aagcttgaca ggtaatttaa atgcatttac cactaatgat ataataattt cagtgtgtat
    29041 atatatagta cttcatatag tatcatttag attgtttaag tgctacaaca cattatggag
    29101 atatgcagga gaagaagaaa ttatatctat ttttgtggca actttagctt atttaattcc
    29161 gatttatata ataaataaat tattagggtt tgattatcct ataatgtttt atgtattaaa
    29221 tacaatattt attataatgt ttacaagtgg cgcaagaata gcctatagag ctataagaat
    29281 agtcatgaac aagacatatt ctagaggaaa ggtttcaaat atccttataa ttggtgcagg
    29341 agatgcagga gaaatggtta tacaggaact aaaaagaaat ccagaactta agaaagtagc
    29401 agtggctata attgatgatg ataaaaataa aattggaaga ataatccata atgtgaaaat
    29461 tgtaggaaca acttcagata taaaagatgt ggtagaaaag tacaatgtag atgagataat
    29521 cttttcaata gcaaacatag agaaacgtag aaaaaaagag attattgata tatgtaaaaa
    29581 cactaactgt aaaataaaga caataccagg aatttacgaa attatagatg gaaaagttga
    29641 tataaagcag attagagaag tagagataga agacttgttg ggtagagagc ctataaaaac
    29701 aaatttaaga gagataagta attacattga gggaaaagta atcctaataa ctggaggagg
    29761 aggctcaatt ggttcagagc tttgtagaca gattgcagga tttaatccta aagagcttat
    29821 tatagttgat aattatgaaa ataatgctta ctcaatacaa caagaattac ttagaaaata
    29881 taaaaataaa ttagatttaa agacagtaat agcatcaata agagaagaaa aaagaatgga
    29941 tgaaatattt aataaatata aaccagaagt ggtatttcat gcagcagcac ataaacatgt
    30001 tcctcttatg gaatctagcc ctggcgaagc tataaagaat aatatatttg gaactttaaa
    30061 catagctggc ttgtcttcaa aatatagagc taagaaattt gtccttatat ctacagataa
    30121 ggctgtaaac cctactaaca taatgggagc tactaaaaga gctgctgaaa tgattataca
    30181 gactatgaat gctgaaagcc agactgaatt tgttgctgtt agatttggaa atgtgcttgg
    30241 tagtaatggt agtgtaattc cactttttaa gaagcaaatt gaagatggcg gaccagtgac
    30301 agttactcat ccagatatta ttagatattt tatgacaata ccagaagcag taggcttagt
    30361 catacaagct ggtgctatgg ctaaaggtgg agaaatattt gtgcttgata tgggagaacc
    30421 tgtaagaata ttggatttag caaaaaactt aattaaattc agtggatttg agccagatgt
    30481 tgatataaaa attgaatttt ctggtcttag accaggagaa aagttatatg aagaactact
    30541 tatgtcagaa gaaggtctgt tggatacaga gcataaaaag atttttattg gtagaccaat
    30601 agatgttgat agagaaaaaa taacaaaata cttaaaactt ttaagagaaa ttactaacaa
    30661 tgaagaggtt gaaaaaatag atggtattat gagggaatta gtgccaactt atattaaacc
    30721 agaagatgct aatatcaaag aaattgcaac aactagagaa aagtagaata tatttctaat
    30781 ttgtaaccag ggggagcaaa aagaaacaaa tatatactaa aaagaaacaa aagattacaa
    30841 aaagattaca aaaagattac aaaaaaggtt gcaatttatt ttgatgtaag atagaatgtt
    30901 aattaggaat tggaaacgaa ggaacaaaat gttaaatttt cgaaaggatt aggtatttga
    30961 gattatgatg aatattaaaa ataaaaaaca tatattgaaa aaatttatag ctatggtgtt
    31021 aatagcagga gttgtcacag tagaagcagg agcaataacg gctagtgcag cagagccaac
    31081 taattcacct atgagtgcaa cagtagacca gtgtgatttt ttaaatgtaa gaagtggagc
    31141 tagtgcaaat gatgcagtag taggaaagat aaacacagga gacaaagttg aagttttaga
    31201 attacattca aatggatgga ttaaaataaa aagtgttgac aatgttacag gatgggtaaa
    31261 tggagattat ttaactattc aaggtggaaa tgtagatgca aaggtacaaa atgttttaaa
    31321 cttagcattt aagcaacaag gtaagccata taaatgggga gcaactggac caaattcttt
    31381 tgattgttct gggttcactt catatgtcta taaaaatgga gcaggagtta atttaccaag
    31441 agtatcaaga tcacaagcaa cagtaggaaa gaaagtatca agagcagaat taaaaccagg
    31501 agatttagtt ttctttggtt caggtggttc aataaatcac gttggattgt atgtaggaga
    31561 ttctaaattc atacattcac cacaaacagg agatgtagta aaagttacta gcatggctcc
    31621 aggaactaat tatgcaaaaa gacttataac tgctacacgt gttttacaat aataatagat
    31681 attgatttac ataggattga atattaacat taaatatata attacattta atgttttaca
    31741 tagagattta agagtttagt aatattaaaa tagtgatgaa cgttataaaa acagcaaaga
    31801 agataaattt ctttgctgtt ttttttataa taaattattt catattataa tcaaatatca
    31861 aatataaatt ttaactatat tattcaatat ttgacagata atatgaattt tagatatact
    31921 taataagaag tatattgtag aaaaaataaa tttaaaaaat taagggggat gaaatgaaaa
    31981 aaataagtat attagtatta tcattgataa tgacacttac tatgtgtagt gtaagttcat
    32041 ttgctgattc atcaaatgat aaggaaatga gagctgcttg gatatctaca gtttataatt
    32101 tagactggcc taagactaag aataatgaag ccaagcaaaa aaaggaatac acagatttat
    32161 tggacaaatt aaaaagtgta ggaataaata cagcagtggt tcaagtaaga ccaaaatcag
    32221 atgctttata taaatcaaat ataaacccat ggtctgaata tcttaccggt acacaaggta
    32281 aagaccctgg atatgaccca ttaccatttt taatagaaga agcacataaa agaggaatgg
    32341 aatttcatgc atggtttaat ccatatagaa taactatggc agatgagagc atagataaat
    32401 tgccagcaaa ccatccagca aagaaaaatc caagctgggt agttaaacat ggaaataagt
    32461 attactacga cccaggttta ccagaagtta gaaagtacat agtggatagt atagcagaag
    32521 tagttcaaaa ttacgatata gatggagttc attttgatga ttacttctat ccaggagtaa
    32581 gtttcaatga tactgcaaca taccaaaaat atggaaaagg acaaaataag gataattgga
    32641 gaagagaaaa tgtaaatact ctacttagag atgtaaaagc gtctataaag agtataaagc
    32701 ctaatgttgt atttggtgta agcccagcag gtatatggag aaataagagt agtgacccaa
    32761 caggttcaga tacatcaggt aatgaaagtt atgtaggtac atatgcagat acaagagcat
    32821 ggataaaaca aggattgatt gactatgtag ttccacaact ttactggcca attggtctta
    32881 aagcagcaga ttattctaaa ttagtggcat ggtgggctaa tgaagtaaaa ggaacaaatg
    32941 tagacttata cataggacaa ggtatatata agcaaggtca atcgagttat ggtggacaaa
    33001 atatagcaaa agaaatagta caacaagtaa cattaaatag aaagtatagt gaaataaaag
    33061 gtagtatgta tttctcagct aaagatatag caaatagtac ttctatacaa aaggatttaa
    33121 agagtttata ttctagtagt gaagaaccag ttactccacc atctaatgtt aaagtggaga
    33181 aattaagagg cgacgaaaga tatgacacag cagtagcaat aagtaaaaaa ggttgggcta
    33241 caaattcaga tacagtagta ttagtaaatg ggtactctat agttgatggt ataacatcaa
    33301 caccacttgc tacatcaaat gatgctccta tactattggt aaataaggat aatataccta
    33361 catccactaa gaatgagtta aaaagactta atccaagtaa agttatttta attggaggaa
    33421 ataactctat tggagataaa gttgagagtg agataaaaga tacattgtca aatgtatcaa
    33481 taaatagagt tggtggttca gatagatata gtacatcttt aatgatagca aaagaattag
    33541 taaaaactaa tccagtagaa aaactatata taacaagtgg tacaggtgaa gcagattctc
    33601 tttctatagc ttcaaaagca ggagaagaaa agcaaccaat agtattagta tcaaaagata
    33661 atgtaagtga tgaagtttac aattggatat cagatttaaa agtaaaagat gcttatttta
    33721 taggtggtaa tctaagtata tctgattcag taataaataa gctggataag gtcattacaa
    33781 atgatgtatc taaaaataga atagctggag aaaatagaga agaaacaaat ggaaaagtaa
    33841 tacaaaaatt ctatccaaat gctgaatatt catcaatgtt tgtaagtaaa agtaatcaat
    33901 tggtagatgc attaacatca ggtcctttag cagctaaatt aaaatcacca gtagttatgc
    33961 ttggaaatag tgtaacatct gctcagaaaa ctgctttaga gcctaagaaa actactctag
    34021 tatacgaagc tggagatggt ataaatcaaa acacattaaa cactttctta aacttagtta
    34081 agtaataaaa aagttaattt aaaatacaga gtattttata aatgtagatt aaaatgaaaa
    34141 ttatcatgat aaattagaaa ataaaaaaga actatatgca ttttgtaatc aagtgtacac
    34201 agcaacttga aaataattat gcgatatagt tcttttttag taattaatct tatacttttt
    34261 aataaacttt atattgaatt ttttattgtt taaactctat gtcattaaat ataaaatcgt
    34321 gtaatatgtc taaagtatct gggtcaaatc taagaaccca tccagctttt ccatatatac
    34381 cacctgtact atgaatttca tcatcaatag gaaattcaaa ttgcttaata tttaagtcgc
    34441 ccatttttaa aacttgagct cctaaagaaa gtattgcatt aggcttcatg ttagttttaa
    34501 catatggaag aactgcatct aataaacctg gatatttagt aacaggtaaa gtttccgttt
    34561 tcttgattat agcttgtata atctgtctct gtctgccatc tctagcaaag gctgtatcgt
    34621 tgtgtctgat acgtgcaaaa gatagtgctt gatatccatt tagagtctgt tttccagagt
    34681 ttctaatgta ttgtatgcta cctttatcat cacttttatt ccatttataa gtttcaggaa
    34741 taaatttatt tagttctcgt atttctcctt tttcaacagt aacctcaacg ccaccaatag
    34801 catcaattat atacataaat gattcgaaat taacacaagc ataattttga atatcaatat
    34861 taaaattctc ttcaattgtt tgtattaata aatcagcttg tccataagca taagcatgag
    34921 taagtttttg tttaccatga ccagggatgt ctacatagct atcacgagct aatgatgtaa
    34981 gtttgatatc attgtgtttg ttatcaatag taagtatcat catagcatct gaccttgaag
    35041 aatcttcatt tggtctagca tctgttccca taagtagtat gttaattatc ccatcttcat
    35101 ttttatggtc attgttatcc aataaatcac tacttatgct cgagtcatga atagcagata
    35161 atttataata aaaatatcca tagacactta tagggaatat tactaccaag aaagccagta
    35221 gtataacaaa tttctttaat tttgacaaaa gtaccccttc tttcttcttt ttcctgtata
    35281 ttttttaata gcatacactt aattatatta aagtattgag atatattcaa tacttgtttc
    35341 agttacaaaa aaaagacaat gatataattt ataagaaaat ttatcgacct atatatatag
    35401 ttaaaagtat atataatata ttttttaaaa gtaatttata ttttaaaata aaaacacacc
    35461 ccataaatac aaagcaattt gcatttaaga ggtatgtatt tatcatcaaa ttattggttt
    35521 gttttggaac ttctaatctt caaccataat atctttaaat atgaaatcat gcattgcatc
    35581 tagttcatat tcctcaaaag gtattacata gcctgcatta cctatttttc taccattttc
    35641 agtagaaaga ggaaactcca tagatttcaa atttaaattt cctatactta aaagttcttt
    35701 tcctaaagat attatttcat taggattcat attagttttt acatacggaa gtattgtgtt
    35761 aactagatta ggatatttag tgactggtaa atccttaaca ccatttatta aactctgtat
    35821 aacacttctt tgtcttctat ctctttcatc tgtgctatca ttttttctta tacgagaaaa
    35881 tgcaagtgtc tgatatccat ttaatttttg ctcaccagaa tttcttatat atttaagaga
    35941 acctttattg tcatttttat tccatttata agtttcagga ataaatttat ttaattctct
    36001 tatttcactc ttatcaacag taacagtaac tccacctaaa gcatcaacta tatccataaa
    36061 agagaaaaag tcaactacgg cgtagttttg tatatcaagt tggaagtttt cttctatagt
    36121 ttctattaat aagttagctt gtccatatac gtaggcatgt gttaattttt gttctccacg
    36181 tcctggtata ttaacataag tatctctatt taatgaagtt agcttaagac ttttattttt
    36241 attatcaata gtaagtatca tcatggcatc agaacgagaa acttcttctc ctggtcttgc
    36301 atctgtacct aacaataata tgtttgtgat attttcttcg tttttatagt cattactact
    36361 aagcgcctct gtatttatac tatcatcttg tatagttttt aatttagtaa aaacatatcc
    36421 atatatacta acaggaaatg ctataactaa aagggctaga aatataacga actttttgag
    36481 tcctgacaat aatatcccct actttctaaa ttttttaatt acacatagtt aattatatta
    36541 aaaatttgtt acataagcaa taaaaaacac aataaattag cataagtttg tcataatata
    36601 attattttta tagcatttta tagaagaaag tgtgtagtta ttattgattt tattggaata
    36661 taattgtatg aagacttaaa tttttataaa ctgatgtgta tattgaaaaa aatattttcc
    36721 tgaatgtagt tatagcatct tatgaaaggt gcaaattgta atttaaaatt tttagtgtat
    36781 aataagaatt gaaaattcaa accgataaaa attaataaaa aataattata aattaataat
    36841 ttgggggagg aaatgtatga taaaattaat agcaacagat ttagatggaa ctttgttaga
    36901 tgaaaagagc gaaataaatc cagagtttta taaagtattt aaaaaattaa gagagagagg
    36961 gataatgttt tctgctgcta gtggcaggca gtatcaaaat cttataaaaa aatttgaaga
    37021 tataaaagat gatatgatgt ttatatcaga aaatggaaca ctagtagtat ataaaggaaa
    37081 agaaatatta tcaaatcctt taaataaaga attagtaaat gaaatcatag agacaacaag
    37141 aagtataaaa gggaaaaaaa ttgtaatgag tgggaaaaaa tacgcttata tagaaagcaa
    37201 agatgaagcg tttatacaag aggtcagtac ttattatgca aagtttaaaa ttgtagaaga
    37261 tttgacgaaa gtagagggag acatattgaa gatagctgta tttgacttca aaggtgcaga
    37321 acataataat aatatctact ttgaaaagtt ttctgataga gctcaagtat gtatttctgg
    37381 agtggagtgg cttgatttaa ctgcaaaagg tgcaaataaa gggagtgcca taaaaaaagt
    37441 acaaaaaatg ttagatataa aatatgaaga aactatggta tttggtgacc agttaaatga
    37501 tgtggaaatg atgaaaagtg cctatcatag ttatgccatg gaaaatgcaa atgaacattt
    37561 gaaacaaatt gctagattta gagcaaaaag aaatactgaa aatggcgttg tagataagat
    37621 aaaagaggtt ataaaaattg gatagtcata tgtatagatg aaaaagatta ttttgaagaa
    37681 atcaaaaaaa tatcaatgta attttgataa ataagtttat ttatgcgaaa attacattga
    37741 tatttaataa acatcaataa tagatattta tttttttatg atattcagta ttttgttttc
    37801 tatttgagtt gcattttcag cagaaattaa ataaacatat ctacctgcct tctcaattat
    37861 agtattattt gctatttcag aattgatttt ttctccatgt ccttctccaa aaggtgcttg
    37921 tatcatatct tttttataat tttctagagt tttatagatt ttatctacct cgtcagtttt
    37981 tataacgata atatcttcta gagataattt ttcagaagaa ttaattacaa aaccttgaat
    38041 tatgtcttcc tctacatcat taaaatagtt aaaatccttt gcatcaaaga tttttgattc
    38101 ctttataagt aaatcagaag attttaatgc tttttttatt tttgatgtag aaacgttttt
    38161 gtaatcacca cttgaagaac aactaaccat tcctaatgat aagattatcg aaaaaaacaa
    38221 tattaaaatt tttttcatga taaacctcca agttttttaa actctgtctt aaattagttt
    38281 actacataat tatataaaaa taaatgtatt taatgttaca gttttgatta ataatgtaat
    38341 attttgataa taatacctat tgagaggtga ttagaaatga gaataccaaa acatgtagga
    38401 attataccgg atggaaatag aaggtgggca agtcaaaatg gtatgacaaa agataaagga
    38461 tatgaaagtg gaatagaccc tggactagag tcttatagat tatgtagaga tttaggctgt
    38521 gaagaggtga ctttttatgg atttacaact gataatacaa gacgtccatc agtgcagaca
    38581 aaagctttta caaaagcatg tattgatgct gcaaatatat taatagatga aggtgctgct
    38641 ttattagttg taggaaatac aaaatcgcca atgtttccag aagaattatt accatatact
    38701 aatagaatta aagccaaaga aggtcaaata aaagcaaatc ttctggtaaa ttatggttgg
    38761 tattgggact taaataatat atcaggagta gaaaatgtaa ataaaaataa tatacaggat
    38821 tacatacagt catttgatgt atccagacta gacttgataa tcagatgggg tggaagaagg
    38881 agattaagtg gtttccttcc tgtacaatca atttatgcag atttttatgt tatagataat
    38941 tattggccag attttaagag tgacgatata aaggacgcat ttagttggta tgatacacaa
    39001 gatgtcactt taggtggata attaaaaata ttctgattta aggttgtaga gtgttttaaa
    39061 ttattgaaaa aaaaacttct tgatggtaaa ataacactaa taatatgtaa aagtgtaaaa
    39121 atttatacca agaagggtga agaaatgtca aaaggcaata ataacaataa ttcaagaaac
    39181 aaatctaaaa agaccagtca tctgaataga aaaaagcgaa aattaaataa gaaaaagtta
    39241 gcagtgttga tttgctttac agttttattt ttatttattg catttaaggc tactcaaggt
    39301 gtagtagctt tggtaaaaag tatggataaa agtaataaaa ctagtcaaca acaaaatgtt
    39361 aactcagaac aatttgacct tggtaatgaa gaggaaaata aaaagaaaaa atatactgta
    39421 tttatagacc caggtcatgg aggcaatgat aaaggaactg aaagcaagac cagtaataga
    39481 tatgaaaaag acctaaatct acaaattgca aaaaaattag caaataaatt atctaaacaa
    39541 aaggatattc aagtagtagt atccagaact gatgatacat atatatcatt aaaggataga
    39601 gctatcttag caaataatag ttctgctgat gtgcttgttt ctattcattt aaatgcagag
    39661 aaaaatggta atacagcaac aggtatagaa acttggtata ggaataaagc tacagatggt
    39721 tcaaaagaac ttgcacagac agtacaaagt actatagtat cctatgttaa agttagagat
    39781 aggggaatag ttgaaaataa ctttgaagta cttagagaat caaatatgcc tgctatatta
    39841 atagagtgtg gttttttaac aacaccttca gaggaacaaa aaataataaa tgaaaaatat
    39901 caagaccaac ttgcggaagg aattgttcaa ggtgtacttt catacctaga ttctaaaggg
    39961 aataagtaag ttaactttac tttaatgtga ggataaattt aaaagtttaa ctgtgtaaat
    40021 tgtattaact ttatttcgta atgttggaaa tattgtttga atttagaaac tatgaaatta
    40081 gaaattattt tatctatatc taatttcata gttttttttg caaaaaattt atagttataa
    40141 aattttaaaa aataaattta gtataatgta atgtagttat ttatatgtga ttttaacttg
    40201 cattgatttg ctatcaattg tgctttataa ttagtatata taaagtttaa ctgtaagata
    40261 atttaaaaaa taggggaatt tatatgaata aaaatagcat gacaagaatt tacagtttaa
    40321 ataaaataat ttttattata attggaattt taggaatagt tttactcaca agacatattg
    40381 aggtagatat taaagtttta attttaattt tattaacctt gtttagtata aatgtattta
    40441 tttcatatct taaaattaag ttgtatgagg ataaaattaa tttaggattg ataaataatt
    40501 cagacaagtt tataaatatt actaaagatg agaacttcct aaaacatgtt caaaattata
    40561 ttatcagtaa tgaaaaagaa aactgtgtaa tggcttgttt tgatttatgt agactcaaac
    40621 ttataaatga tatatatggt tatgagctag gggatgaagt gttaaataat attttaagta
    40681 acttaaaaaa ttattttgga aaagaagcta tttatggaaa gttaaaaagt gatgtttttg
    40741 tattaataat aaagcttgaa aatagggaac agaagattcc ttatttagta aatcttatta
    40801 agaataaaat tgtgatacta agtcagattg acagttttaa aatggatata aatattgagg
    40861 cttctattgg aatttataaa tttaacaata atgaaattga tataaaaaaa gctatagata
    40921 atgctgatat ggcaaggctt aaatcaaaag gattaaagca catagagtat gtagaatttg
    40981 ataatgctat ggaagaagaa atacaatcaa ttatgaaaat agagagagat ttattcttgg
    41041 ctattaaaaa taaagagttt gtaattcact atcaacctaa agttgattca agtacaggta
    41101 acattatagg ttcagaggca ttgataagat ggttgcaccc atcattaggc atggttggac
    41161 caaataagtt tatacctata gctgaaaaaa atggtctgat aaacaatatt ggtagatggc
    41221 taattcaaga agtttttatt accattaaca agtggatttc agaaggtata aatgtcttac
    41281 cagtctcaat aaatctttct agagtagaac tatataaaaa tgatttagtt gattttttta
    41341 aactgatgtt taatacatat aatattccaa aagaacttat agaattagaa attacagaaa
    41401 cgacagcact aagagatgta aaatttataa gtgaaaggct ttatgagatt aaatctttag
    41461 gtatgaatat atcattagat gattttggag taggtaattc aaattttatc aatcttaagg
    41521 ggataccact agatattata aaaattgata ggtcacttat attggatata gttacaaata
    41581 caaaaacaaa gtttatggtg aaagcaattg ttaacctttc acatgattta aacgtaactg
    41641 ttatatgtga aggggtagag gatatgcatc aggtcaaagt cttaagtgaa ctgggatgta
    41701 atttcataca aggttatgta ttttttaaac ctttggatga gatgaattat aaaaaacttc
    41761 ttactgacgg aagttatata aatctgaaag atactctttt agataaatgc atgacagttg
    41821 aggaggagta aggatgattt cagaagatgt agattattca ataagaatca taagagctat
    41881 atttaataat ggagaagata aaccaataga tgctaaaatg atattaaaaa gtgaagatat
    41941 accaatacta acactataca gactgcttag aaagctttgt gcaaacaata ttcttacttt
    42001 taacaaagaa gatggcaaga catacatgtt aaatgtgtca ttggatacaa taagtctaag
    42061 aactattgta gaagtaattg atggaaaaat atatataaat aaatgtacga gatatgtatc
    42121 taattgcagt aattgcttaa aaggttgtaa agtaaatcgt gaattgctag aaatagaaaa
    42181 agaaatttat aaacttttat cgagaaaatc tataagacaa atactagaat aaaaaatttt
    42241 cagctatgat aataattgga ggttttcggt tatggatgat atatctcaag ataattttct
    42301 actgtctaaa gagtatgaga atagcttaga tgtagatact aaaaaagcaa gtggaatata
    42361 ttatactcct aaaataattg tagattatat tgtaaaaaaa actttaaaaa atcacgatat
    42421 aattaaaaat ccatatccac gaatacttga tatttcctgt gggtgtggaa attttctttt
    42481 agaagtatat gatattttat atgacttatt tgaggaaaat atatatgaat tgaaaaagaa
    42541 gtatgatgaa aattattgga ctgttgataa catacaccgt catatattaa actattgtat
    42601 atatggtgct gatattgatg aaaaagctat aagtatatta aaagatagct taacaaataa
    42661 aaaggtagta aatgatttag atgaatctga tataaagatt aatctatttt gttgtgatag
    42721 tcttaaaaag aaatggcgat ataagtttga ttacatagtg ggtaatccac cctatattgg
    42781 tcataaaaaa cttgaaaaga aatataaaaa atttctccta gaaaaatata gtgaagttta
    42841 taaggataaa gctgacttat atttttgttt ttataaaaag attatagata ttttaaagca
    42901 aggagggatt ggcagtgtta taactccaag atatttttta gaaagtctat caggtaaaga
    42961 tttaagagaa tatattaaat caaatgtcaa tgttcaagaa atagtggatt ttttaggtgc
    43021 aaatatattt aaaaatatag gggtatctag ttgtattcta acttttgata agaaaaaaac
    43081 aaaagagaca tatatagatg tatttaaaat caaaaatgag gatatatgta taaataaatt
    43141 tgaaacattg gaagaacttc taaagagtag caaatttgaa cattttaata taaatcagag
    43201 attgctatct gacgaatgga tacttgtaaa taaagatgat gaaacttttt ataataagat
    43261 acaagaaaaa tgtaaatata gcttggaaga tatagcaata agttttcaag gaataattac
    43321 agggtgtgat aaagcgttta ttttaagtaa agatgatgta aagttgaacc ttgtagatga
    43381 taaattttta aaatgttgga taaaaagtaa gaatataaat aaatatatag tagataaaag
    43441 tgaatatagg ctaatatact caaatgatat agataatgag aatacaaata aaaggatact
    43501 agatgaaatt atagggctat ataaaacaaa attagaaaac agaagagaat gtaaaagtgg
    43561 aataaggaaa tggtatgaac ttcaatgggg tagagaaaag cttttctttg aaagaaaaaa
    43621 gataatgtat ccttataaat caaatgaaaa tagatttgct atagattatg ataacaattt
    43681 ttcaagtgca gatgtatatt ctttttttat aaaagaagag tatttagata aattttcata
    43741 tgaatatcta gttggaattt taaattccag tgtttatgat aaatacttta aaataactgc
    43801 taaaaaaatg agtaaaaata tatatgatta ctatcctaat aaggttatga agataaggat
    43861 ttttagggat aataattatg aagagataga gaatttatca aagcaaataa tatcaatttt
    43921 attaaataag tctatagata aaggaaaagt agaaaaattg cagataaaaa tggataactt
    43981 gataatggat tctttaggta tataagcagt tgtaagtatt aaaaaattat aatcttttaa
    44041 ttgtttattt aaatttagaa ataaaaagtt agccatataa aaaatattaa aaatatatac
    44101 ttttcaatat ttttttgata aaataagaat gaatttgtgc aattttattt ttctccaata
    44161 actaaaaata gttttttgaa ttaatatttg cttaagaata aaaatcagaa acgtttttga
    44221 tatagtaggt gataatatga aaggattagt tttagaaggt ggaggaacaa aaggagccta
    44281 ccaaataggt gcatataaag ctttaagaga gcttggtata gagtttcaag gagtaactgg
    44341 cacatcaatt ggtgctttaa atggagcata tataattcaa aatgatattg aagtaatgga
    44401 agatatttgg ttaaattatg actatactca ttttatgaat attgatagag aaacctatga
    44461 gaggtttaaa aatgtagatt tcactactaa aaatctcaat gcagtgtttg agcttataaa
    44521 taaagctaga aaaaatgaag gtatagatat aagcccatta agacaattaa tggagacaac
    44581 attaaatgaa gacataataa ggaaatcaaa aaaagacttt ggacttgtta cggtctggtg
    44641 ggataaaaaa attaatccat atccattgta tatcgaagat atacctaaag gaagattgat
    44701 tgattattta attgctagtt ccagtttgcc tatttttcaa acgaacatga tggatgataa
    44761 gttgtatctt gatggaatgt tttgtgataa catgccaata ggactcttgg aagacaaagg
    44821 ttatgaagat gttgttgtaa ttaggttgat tgatgatttt attgggaaaa tgaatctaaa
    44881 tcgacatcaa aatataaata taaaaactat aataccatca gaatatctag gaggttctct
    44941 taataaagat agagataatg tagaaaaaaa catccgacta ggttacttag atactatgaa
    45001 agcatatgaa agatgcactg gaattaagta ttattttgat gtagagtata aatataatga
    45061 agaatattgt tttgataaat ttagaagtat gagcaatgaa acaatacaat atatctgtaa
    45121 tttattgaat ataaaaagag atgcttcact tagaaccgtt atggaaagtg taataccaaa
    45181 gcttggtgag gtgcttggat tgccaaagga tttttcatat aaagatttgt tttactgtat
    45241 atatgaaaag aaacttgaag aaaataatat aaacaggata aaattatatg attttaacaa
    45301 ggttatagat gttgtaaata caaatattga ttctaataga aatttagctt ctaattttga
    45361 agttagacct aaaattagta ttaaaaagaa caaaaacaca aaattattga caaattgtat
    45421 tataaaagac ataaaaaatc aaagttaaat aaaaaacaaa aaaaaatttg taattatact
    45481 cgaaaaaagt gtatattagt agtataatat ttttgtagca ctagtgggaa caaaaaatga
    45541 ccataggaca aaaaagtacc acttagtacc attaaagtaa aaaacaggaa aacaatttta
    45601 aaaaatataa aatgtaaagt ttataggagg atttaaaaaa atggaaaaag tagttagtat
    45661 caaaaatgca agtggattac atgctagacc agcaggaatg tttgttaaga aggcagctga
    45721 atttaaatca acagtagagg ttgtagcaaa agacaaaact gtaaatgcaa aatcaataat
    45781 gggaataatg agtttaggtt tagctcaagg agaagaatta aagttagttg taaatggaga
    45841 agatgaagaa gtagctttag ctgcaatggt tgaattagtt gaaagtggat ttggagaata
    45901 gatataataa ttttttaaaa atttgatatt tagaatctaa tattacttaa agtaaagtaa
    45961 cagagaagta ttaaacatat acagaccaac atttgtagat atttaatttc tttgttactt
    46021 tcatgtttat ttaatcagaa gattaagact attgttaatt gggtataaaa atataaatat
    46081 tttagaaaat gaaataagat atttttaatc ataaattcag agtaaaaata cagtaacaaa
    46141 tagtttataa aattttataa a
//
LOCUS       DAEPXW010000024        46141 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.024, whole genome shotgun sequence.
ACCESSION   DAEPXW010000024 DAEPXW010000000
VERSION     DAEPXW010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46141
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.024"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            124..507
                     /locus_tag="KRM55_001270"
     CDS             124..507
                     /locus_tag="KRM55_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1593520.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            509..859
                     /locus_tag="KRM55_001271"
     CDS             509..859
                     /locus_tag="KRM55_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593521.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(960..1418)
                     /locus_tag="KRM55_001272"
     CDS             complement(960..1418)
                     /locus_tag="KRM55_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593522.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYAPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(1463..2251)
                     /locus_tag="KRM55_001273"
     CDS             complement(1463..2251)
                     /locus_tag="KRM55_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1593523.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGNVVINGADRYETVKLALQEIDKL"
     gene            complement(2390..2827)
                     /locus_tag="KRM55_001274"
     CDS             complement(2390..2827)
                     /locus_tag="KRM55_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH1593524.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            3649..4158
                     /locus_tag="KRM55_001275"
     CDS             3649..4158
                     /locus_tag="KRM55_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1593525.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            4563..5099
                     /locus_tag="KRM55_001276"
     CDS             4563..5099
                     /locus_tag="KRM55_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBH1593526.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFLGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKR"
     gene            complement(5539..6339)
                     /locus_tag="KRM55_001277"
     CDS             complement(5539..6339)
                     /locus_tag="KRM55_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593527.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(6534..8132)
                     /locus_tag="KRM55_001278"
     CDS             complement(6534..8132)
                     /locus_tag="KRM55_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1593528.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTDSTASDYIVSQIESLNNEIS
                     ILKDKINTLESGNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            8460..8636
                     /locus_tag="KRM55_001279"
     CDS             8460..8636
                     /locus_tag="KRM55_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593529.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            8810..9940
                     /locus_tag="KRM55_001280"
     CDS             8810..9940
                     /locus_tag="KRM55_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH1593530.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            10181..10531
                     /locus_tag="KRM55_001281"
     CDS             10181..10531
                     /locus_tag="KRM55_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH1593531.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            10539..10988
                     /locus_tag="KRM55_001282"
     CDS             10539..10988
                     /locus_tag="KRM55_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HBH1593532.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            11090..11665
                     /locus_tag="KRM55_001283"
     CDS             11090..11665
                     /locus_tag="KRM55_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH1593533.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            11658..13067
                     /locus_tag="KRM55_001284"
     CDS             11658..13067
                     /locus_tag="KRM55_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HBH1593534.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            13251..14684
                     /gene="eutA"
                     /locus_tag="KRM55_001285"
     CDS             13251..14684
                     /gene="eutA"
                     /locus_tag="KRM55_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBH1593535.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQIGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYAVLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            14702..16066
                     /locus_tag="KRM55_001286"
     CDS             14702..16066
                     /locus_tag="KRM55_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HBH1593536.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            16079..16960
                     /gene="eutC"
                     /locus_tag="KRM55_001287"
     CDS             16079..16960
                     /gene="eutC"
                     /locus_tag="KRM55_001287"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HBH1593537.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            16980..17633
                     /gene="eutL"
                     /locus_tag="KRM55_001288"
     CDS             16980..17633
                     /gene="eutL"
                     /locus_tag="KRM55_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBH1593538.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            17644..18345
                     /locus_tag="KRM55_001289"
     CDS             17644..18345
                     /locus_tag="KRM55_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH1593539.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKELKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVNDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EEIINLVKKLSRRDR"
     gene            18348..19817
                     /locus_tag="KRM55_001290"
     CDS             18348..19817
                     /locus_tag="KRM55_001290"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBH1593540.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKAAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            19913..20200
                     /gene="eutM"
                     /locus_tag="KRM55_001291"
     CDS             19913..20200
                     /gene="eutM"
                     /locus_tag="KRM55_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HBH1593541.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            20327..21088
                     /locus_tag="KRM55_001292"
     CDS             20327..21088
                     /locus_tag="KRM55_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HBH1593542.1"
                     /translation="MGVLTENEVKRKIGKSKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            21101..21730
                     /locus_tag="KRM55_001293"
     CDS             21101..21730
                     /locus_tag="KRM55_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH1593543.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            21772..22497
                     /locus_tag="KRM55_001294"
     CDS             21772..22497
                     /locus_tag="KRM55_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HBH1593544.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            22510..22782
                     /locus_tag="KRM55_001295"
     CDS             22510..22782
                     /locus_tag="KRM55_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBH1593545.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            22775..23326
                     /locus_tag="KRM55_001296"
     CDS             22775..23326
                     /locus_tag="KRM55_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH1593546.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMVKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            23338..24429
                     /gene="eutH"
                     /locus_tag="KRM55_001297"
     CDS             23338..24429
                     /gene="eutH"
                     /locus_tag="KRM55_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH1593547.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLIGGITAVLLAMVIANKTLKKENV"
     gene            24431..24904
                     /locus_tag="KRM55_001298"
     CDS             24431..24904
                     /locus_tag="KRM55_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HBH1593548.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(25024..25125)
                     /locus_tag="KRM55_001299"
                     /pseudo
     CDS             complement(25024..25125)
                     /locus_tag="KRM55_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            25420..25941
                     /locus_tag="KRM55_001300"
     CDS             25420..25941
                     /locus_tag="KRM55_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1593549.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            26320..27495
                     /locus_tag="KRM55_001301"
     CDS             26320..27495
                     /locus_tag="KRM55_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1593550.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            27529..29067
                     /locus_tag="KRM55_001302"
     CDS             27529..29067
                     /locus_tag="KRM55_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH1593551.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGEYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISESTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            29099..30301
                     /locus_tag="KRM55_001303"
     CDS             29099..30301
                     /locus_tag="KRM55_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1593552.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(30468..31067)
                     /locus_tag="KRM55_001304"
     CDS             complement(30468..31067)
                     /locus_tag="KRM55_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1593553.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            31237..32595
                     /locus_tag="KRM55_001305"
     CDS             31237..32595
                     /locus_tag="KRM55_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593554.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            32588..33220
                     /locus_tag="KRM55_001306"
     CDS             32588..33220
                     /locus_tag="KRM55_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH1593555.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            33549..34706
                     /locus_tag="KRM55_001307"
     CDS             33549..34706
                     /locus_tag="KRM55_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1593556.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(34853..35488)
                     /gene="lexA"
                     /locus_tag="KRM55_001308"
     CDS             complement(34853..35488)
                     /gene="lexA"
                     /locus_tag="KRM55_001308"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBH1593557.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(35592..36719)
                     /locus_tag="KRM55_001309"
     CDS             complement(35592..36719)
                     /locus_tag="KRM55_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1593558.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(37040..37885)
                     /locus_tag="KRM55_001310"
     CDS             complement(37040..37885)
                     /locus_tag="KRM55_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593559.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(37915..38286)
                     /locus_tag="KRM55_001311"
     CDS             complement(37915..38286)
                     /locus_tag="KRM55_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH1593560.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(38439..38699)
                     /locus_tag="KRM55_001312"
     CDS             complement(38439..38699)
                     /locus_tag="KRM55_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBH1593561.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(38888..39832)
                     /locus_tag="KRM55_001313"
     CDS             complement(38888..39832)
                     /locus_tag="KRM55_001313"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBH1593562.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(39853..40707)
                     /locus_tag="KRM55_001314"
     CDS             complement(39853..40707)
                     /locus_tag="KRM55_001314"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBH1593563.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(40722..42083)
                     /gene="accC"
                     /locus_tag="KRM55_001315"
     CDS             complement(40722..42083)
                     /gene="accC"
                     /locus_tag="KRM55_001315"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBH1593564.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     LNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(42099..42551)
                     /gene="accB"
                     /locus_tag="KRM55_001316"
     CDS             complement(42099..42551)
                     /gene="accB"
                     /locus_tag="KRM55_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBH1593565.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(42821..43267)
                     /locus_tag="KRM55_001317"
     CDS             complement(42821..43267)
                     /locus_tag="KRM55_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593566.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            43542..43820
                     /locus_tag="KRM55_001318"
     CDS             43542..43820
                     /locus_tag="KRM55_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593567.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(43949..44695)
                     /locus_tag="KRM55_001319"
     CDS             complement(43949..44695)
                     /locus_tag="KRM55_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593568.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(44824..45468)
                     /gene="trmB"
                     /locus_tag="KRM55_001320"
     CDS             complement(44824..45468)
                     /gene="trmB"
                     /locus_tag="KRM55_001320"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBH1593569.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(45606..45926)
                     /locus_tag="KRM55_001321"
     CDS             complement(45606..45926)
                     /locus_tag="KRM55_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBH1593570.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
BASE COUNT        17434 a         6150 c         7044 g        15513 t
ORIGIN      
        1 aatgaatagg aagtaattaa aaagaatttt tattgatttt taaaaattta gttagaaact
       61 atatcattat ggtaaaaaat gtattataat gtttagaaat attataataa ggagcgatta
      121 aacatgaatc tatcgaagaa aatagaagat aaaagaaaag ctaaacagag agctgaaaaa
      181 gttaagaaag ctaaaattgc tacagctggt gtggtattag gagctgttac tggtgcagtg
      241 agtggagtac ttttggctcc taaatctgga aaagaaacaa gagaggatat aaaagatgct
      301 tcacaacaaa ttgctgaaaa gataaatatg aaaactgtag atgtaaaagg caaagtatct
      361 gagaagctag aggataaaaa aggaaacttt atagaatcaa agaaaaaaat aaaaaaatat
      421 atagataaca aaaagagtgt tgaaaattct agtgaggaag ataaaataat agatatagtt
      481 gaaccagtta gtgttactga ggaataatat ggacaataca ataacgatta acataagtat
      541 aatatatgta ttattagcta tacttgcttg tattgcttta gtttatttaa ttattgtact
      601 tgttaaacta cataagattt taaataatgt tggaactatg ttaaatgaaa atactcaaaa
      661 tataaataca actttaaata atcttcctaa tgttgtagaa acttttggag aagtaggaga
      721 aaatatgaaa gatgtaacag aagtagttac tgaagttaca gcagattttc ttgttactaa
      781 agacagtgtc aaatcaaata tggatgttat agttgatata ttgactataa ttaaaaacat
      841 ttttctagat aaaaaataat aagttaatat aaaataagcc tataagatat aatttaaacg
      901 accttaaaat agcatttata aggtcgtttt ttattagctt gatttgacac tatgtgtttt
      961 taataattgg taatattcct ctttatcatt tgaacatata tatctatgct tgttgtttca
     1021 attacatcca taagaacatc tttacattca agctcaaaat cttccattcc ttctaaatat
     1081 tcatcatctt catcaaaaaa gatataagaa ttatatagcc attcttcaaa tttttcttca
     1141 agtatatccc aatacgaact ccaaaataat ccacaacctg atatataaga tgctctactt
     1201 tgatttatat aaacctcatt tagaagcttt tgtaatctac tgctataaag aaaatctgct
     1261 cttccactgc ttgatattaa ttcatttaaa tcttctattg acattaattc aactttacca
     1321 cttttatcat aaggagcata attttcatca acccatttat gtggtttgtt ttctctgcat
     1381 actgttgcta tcaactctac aacttttgtt cttatcattt ttttatccta acttatttat
     1441 tttttataaa ataatcatga ttttataatt tatctatttc ttgtaatgct aatttaacag
     1501 tttcatatct atcagcacca tttattacta cattaccttt tacaagttta ttagcttctc
     1561 cacctacaac ataaaccttt ttacctaaac cttgcttata actagacgcc tcaattatta
     1621 aagaatcttt caattgccaa tgtaaaatct gagcagccac tttatcagca tcacctgtat
     1681 aaacgattac attttcatac actttatttt cccctccccc ttgagaattt gatatagatt
     1741 tgtttagtat accttctgct atcaatttag caactttatc tttattatta acataataat
     1801 ctgtatctgc tttactatct acaaaacata cttctattaa tattgctggt gcaatagtat
     1861 gattaagcca ataaagacct ctaacatcag actttgcacc cctatctttg aatactgtag
     1921 ctaacctagt attcactctt tctgcatagg ttttgccatt attagtctta tatattgttt
     1981 ctgtccctac tggagttgaa gttgtagcat ttgaattaaa atgaatctga acagccaaat
     2041 cagtttcctg tttatttgct atagcacatt ggtctgctaa atgattactt gattcatcaa
     2101 ctcttcctgt ataaacagta gctccaccta ttttaagcca tttaacaatt aagtcattca
     2161 gtattcttgt ttctttgctt tcgtttatat acccaacagc tcctgtacct tttccaatta
     2221 aagtgtgccc tggtattatt actactttca aactaacatc tcctttacaa ttaaatttaa
     2281 cttctattta atatatgcat aacctagaat tttgtttctt tttatatctt atacttttat
     2341 tataacccat tttgtaaaaa tatagaatat taagtaaata atgttaaaat tataattttg
     2401 tatataagac attacttgat tgcaataatt ttatagcata ttcatctatt ctatatccag
     2461 ttctataata tatatgttta attccagctt gaattatagc cttagtacaa tttaagcaag
     2521 gaaagtgagt tacataaata gagcaatctt taactgaaat accttctttt gcacaataat
     2581 aaagggcatt ttgttcagcg tgaatggttc taatacaatg tccatctctc atttcatgac
     2641 caacttcact acaatgctta tctccagaaa tactaccatt atatccagta gacactattc
     2701 tgttttctga attgacaatt atagctccta cataagctct atcacaagtt cctctttcag
     2761 ctactgtttc gcacagtctc ataaaatatt cttgccatga gcatctattt tcaagttttt
     2821 tattcaaatc atatacctcc aaaatttata tctaatatat aagatttata ccttaaaaat
     2881 agtattaaaa acaaatttat acgataaata aaatttatta atactgtttt tagtctaaat
     2941 tatttcattt taaattaaag ttacaaggaa tctaaaatta tatatatctt tcttcgtaat
     3001 atgaatgtta caatataaaa aactgtctca ataaaataga gacagtttta cagtcaaagt
     3061 ttataataca agttcatatt tttctttaaa ttcttttaca gcttcgggcc atgccttttg
     3121 ttctgtaata cctttttctt tagctatttt aattgcaatc tctcttatca ttgcagcgcc
     3181 ttctaatatt cccattttta atctcccttc aaatatcttt ttgtatagaa tataaatagt
     3241 gctaagattt attacatgct gcatatacaa tatctataca acacataact tgtaaattcc
     3301 ttttattttc atacgtcttt aaccgacata taattatatt caataagttt taaaattatg
     3361 aactcaatta taattatttt tattttttta gaatctaaac actaaaaatt gtaggtaaat
     3421 ttgtcttatg cctttataaa tatttctaca gttttaatta ctggacatat ctatttttat
     3481 tataaaaagc gattaaaaat ggagaatatc ctcataaaaa ctgtatataa gcaaaacggt
     3541 taaaggaaaa agaagaaatt taattgaatg ttaaaatgcg ttgcttgaag caatgggcag
     3601 ttttgcctat aatatcggta acaactgaaa gaaaggtggt tagccctaat gttaagcgaa
     3661 aacattaaaa caatcaggaa gtcaaaagga ctttcacaac aagaacttgc tataaaactg
     3721 aatgtagtgc gacaaacaat atctaaatgg gaacaaggac tgtcggttcc cgattctgat
     3781 atgttgattt ccatatcaga ggtgcttgaa acgcccgtaa gcactttact tggagaaact
     3841 attgttgagt cggaagttga taacttaaaa gtgatttctg aaaaattaga gattataaac
     3901 ttgcaacttg cacaaagaaa aaacatgaga agaaaaatgt ttcattggtt atttatttta
     3961 ttatgtgcag tcatattaat agtttttgtg gtcttaggga gactaaatag tccttacttg
     4021 gattggaatt ataccgaccc tgaaaccgct gtttttggag tagcttttca tgcttttgag
     4081 tggctatttg tcagattagt accgattgtc cttataggag caattattgg aatctttttg
     4141 acacgtaaga aaatatgaag taactctgct ttttataata cagcaagcgt tccttaaaag
     4201 cgtcattcta catggcaatc gaggacgact atgtaaggaa gaaccttttg gatttccaac
     4261 taagcgaagt tattgaggac gacagtaggc ccaaaaccgc attaagtaaa gtacaggaag
     4321 caagactgct ggacttatac tctcatgcgt aagatgcagg aaatgcgagg tctggtagca
     4381 tgatttacaa cgatttgtac aacgactacg agtagaaata tatggagata agtattatct
     4441 acgaaatcag aaaagaaatg acttgataat ttactcatgt tataattatt gatgtgaaat
     4501 taataaatcg aaattccttt tttggattta acaatactga gtaaggaaaa agtgaatgac
     4561 ttttgcaagg aggtgttaat atcaggcaag taaagtcttt tgtttttcca gttatatcct
     4621 taatattctt agaccaaatt agcaaagttc ttataggatt attcttaatg gactttgaaa
     4681 ttgatataat tgggaaattt ttaagattca atcctgttca aaatacaaat ctctcttatg
     4741 ggggaaactt tattggtatt ctatctaatt tatgggtatt ggtattgttt aacattttag
     4801 ttatattagt tattatatct ggatatgctt tttataaatc aaaaaatgaa caaacaagct
     4861 attcagtaaa agtaattatg tcttgtggac ttgctggtac aatatgtagc ttgatagata
     4921 aattattttt gggaggaagt ttagattttt tgcagatacc aagctttttt attttcgact
     4981 taaaagactg ctaccttact gttgcagaaa taatatttgt tgttatagga attttgcata
     5041 atagagaaat atcaatgaaa gaatacatat atttttgcta tcgtcagttt aaaagataaa
     5101 tttagaagat aaatttaagt ttcaaggtaa acttatttaa tcacagcaaa tagttggctt
     5161 acttaagctt ttgggctaaa ctgtgagcac taattaagtc tctgctatct aacaaacgga
     5221 gcacaaaaat aaaaataaaa attaaatatt aaatataaag cacagttaat tttgattaaa
     5281 aagttgactg tcttttcttt tgtagaaatt taagcatagg taataaagaa atgactgcat
     5341 ttaagcatta tgtatataat tggaggcaat aaaaagccag caaagcccat aaaatagagc
     5401 tgtgctagca acatgatgag ttataagaag ataatcaaaa acttacgctt tattttaatt
     5461 taaaaaaatg attactgtaa agaaatcatt ttttattata atcactgata catcaaatat
     5521 tctaaataaa atttttattt atctggaatt gtatattttt tctataatat taactacagc
     5581 gtacattgcc caagcacaga tagccaatac aaatactccc atcattacta aatctaattt
     5641 aaatacttga gaaccatata ctatcaagta gcctattcca tatcttgaaa ctaaaaattc
     5701 tccaactatt acacctaccc atgccatacc aatattaatt ttagttaaat ttattaaatt
     5761 tcctgtgttt gcaggtaata tgagtttaaa taatatttga gatttagtag ctccaaagct
     5821 ttttaacatc ttaatttttt cttcatctat attcataaaa taattataag ctgaaagtat
     5881 agtaacaaca acagaaatcg ttacagctgt tacgacgatt ccttctattc cagcacctac
     5941 ccaaactata attataggag ctaaagcagt cttaggaaga gcatttaaaa ctaccaaaaa
     6001 tgggtctaat atttttgata atttttctga ccaccaaaga gcaattgcta ccaaaatacc
     6061 taatacagta cctataacaa gaccaagaac agtttcatat acagatattc caatatgttt
     6121 aaataattga ccactaaatg catattgaat aaataaattg taaatatcac ttggtttgct
     6181 aaatagaaat gtatttataa catttaagtc agctaaaagt tcccagatta caataaaacc
     6241 aattaaaatt aatagctggt agaataatac atttcttttt tctcttttta cacctttaac
     6301 atagtttata tatccttcag atcttttatt aagcctcatg tgtatctagc tccttccata
     6361 atatgtcgaa atacttttga aaatcaggaa ctttacgtgt tttgagaggc gtttttgttc
     6421 catccatgtt aagttcaata tcgtaaatat tttttatggt agctggtctt ttagatagta
     6481 ttgcaacctt atctgatatg cttattgctt ctgctatagc taaaaaagtg caactaattg
     6541 cttaaagaaa cagaattatc cacttcagca cccatataaa caatattaag atttcctaaa
     6601 ctgctatccc aaacgatact attaataata gtagataata acaatctctt atcatctaaa
     6661 ctggcattat caacttcatc attaaatctc ttcaaattac taacaataat atcaatatta
     6721 atactgtcac tactaatatt gatgttacca gattccaaag tattaatctt atcctttaaa
     6781 atactaatct cattatttag gctctcaatc tgggaaacta tataatcaga agcagtacta
     6841 tcagtatttt ttgcaagctc tataactaaa tttttaataa gtctttcctt atctaaaatt
     6901 tgatttttaa gtaaattagt ctcagattta aaaatattaa aaacattatc agtcttaatg
     6961 ttattactat tgaatgcact tataatagac tcttctttac aattcttaat tttatctata
     7021 actaaacttt caactaatgg accattaaga tttttacagt tgcaactatc agacccaagt
     7081 gtttttttag taccacaaat ataataatac tttaaatcct tgtcagtttt tttgccttta
     7141 taggtaattc tcatattaga accacattta ccacatttta taagaccaga taaaagagca
     7201 gtttttccag ttgatatcct tggagtttta tcacgatttt tatctaattg attttgtact
     7261 tcaagccata tttcaggttc tatgactcca tggtgttttg caattgctgc tattgagtta
     7321 gatgtatttt tagcataagt aaggattcca cattttctat ctggagtacc tacaacatcc
     7381 ataccactat ttttaaggta atctaaaatt tcatcattag cttttacata tgctggattt
     7441 ctaagtattc tagataaaga actagggtca aatttaccac cacgaggacc ccttattcca
     7501 ttattataga catatttata taacttagat aaggacctaa gttctaaata tttattgtat
     7561 attagcttta caatctccat ttgttcatca tttacttgaa gcttatacat acttctttct
     7621 tttagatttt catctaagaa tgtgattttt tcactgttga atccatgagg tgtattgcct
     7681 ccaagccatc taccactacg ggctaattca tacatattgt cttttatacg ttctgctatt
     7741 gtttctcttt ctaattgagc aaatacactt gatataaaca tcatagctct tcccattgga
     7801 gttgaagtat caaattgttc tttgatagat ataaatgata tgtttagttc atttaatttt
     7861 tctattaaag tagagaagtc agatacattt ctcgatatcc tatctaatct ataacaaact
     7921 aggtaactaa atttcttatc tttggcatcc tgcatcattt tcttaaattg tggtctatct
     7981 atattgctac cactaaatcc ctcatcttca tatatcaaaa aatcttttac accaatagac
     8041 tttgcataat caatacataa ttgtatttga ttttctatag aatcaccttt tccagtaaat
     8101 cttgattttc ttgaataaat tgcagctttc aaaattaaaa cctcctataa gttaggatat
     8161 atatttgaaa ctatttatct acaacctttt aagtaaactt attagaatga atttattaat
     8221 taggtaaatt tatataattc tactttttat aatatatgac tatttatttt atttctttac
     8281 tattcaagtt ctaaatcaat aataaatttt gatatttaat tgtatcagga caaatctcta
     8341 atttcataga ttattaatat aaaatcatag gttagtgtga aaaagttgaa atttaaatat
     8401 tttaaaagat aatttttttg aactaatagg tataacaaaa atttataggg ggattgcata
     8461 tggaaatcaa tgttatagaa attttcccta aagataaagc taaacttaat aaaatagaaa
     8521 tggataaagc tagttggttt gtaaatataa taagtaaaaa atatcctaaa gaagctttaa
     8581 atgaagcatt tagtacttta gaaaaagaat taaatataag taaagctaat acataagctt
     8641 tgattattga ttttatatac tattggtttt atacgctatg acttgacatt atattaatca
     8701 aatagtatat ttttaaatat agcacaatga agtgttaaaa gagcaatgga gctccataga
     8761 taaagtctat ggagcttttt tgcgtattta acttaaggag gataggactt tgaataactt
     8821 tgagattaaa actagaataa aatttggaga aggttcacta aaagctttgc aagaattaaa
     8881 aaacaaaaat gtactaataa taacagaccc ttttatggtg aaatcaaaaa caatagataa
     8941 aataacatct aatttaataa actcaacata tcaagttttt gaagaaatag taccagaccc
     9001 accaatagaa gtagtagtag caggaataga agcatttaaa tctataaatc cagacgtaat
     9061 aatagcatta ggtggtggtt ctgcaataga tgcagcaaaa tctataatgg acttttctaa
     9121 aaaaatatta aaaattaacg aagtagagtt tatagcaata ccaacaacaa gtggaacagg
     9181 ttcagaagta acatcatttg ctgtaataac agatagtcaa aaaaaatgta agtatccatt
     9241 agtgagtgat gatttacttc cagatatggc aatactagac ccagaacttg taaaaactgt
     9301 accaaatttt ataacagcag atacagggat ggatgtattg acacatgcta tagaagctta
     9361 cgtatctaca aattctaatg acttttcaga tgcactagct gaaaaagcta taaagttagt
     9421 atttaaatac ttaataaaag catataaaga tggaaatgac atagaagcta gagaaaaaat
     9481 gcacaatgca tcttgtttag caggtatggc atttaaccaa gcatcacttg gcataaatca
     9541 ttctattgca catgtattag gtggaaaatt ccatatacca catggaagaa caaactctat
     9601 attacttcct catgtaatag aatataattc atcaatagta ggatatacta acacaactta
     9661 ctctgctaca gctaaaaaat atgcacaaat agcagaatta gtaggacttg ggagtgctaa
     9721 tataagaata tctgttagaa atttagtaaa tgaaataaag aaactacaaa aagaaatgaa
     9781 tatgccaact aaattgacac aatgcaaatt aagtttagaa gatataacta atgaagaaag
     9841 agaaatagca aaacttgcta taaaagatac ttgtacatta actaatccta aggtaccaac
     9901 tgaagatgat ataataaaca tattaaagaa cattaaataa ctacatttta ttacatgtaa
     9961 atataatatt atacaaatag ggaaaatgtt tttaaaaata taaattatat attgacaaat
    10021 ataaaacata aaactataat gaaagtatca caaaggcgtg atactttagt agaaagcaat
    10081 ggagcttctt aggaatatta atattattct tatggagctc cttttatttt aatcaaatag
    10141 ctttttaata aactatattc aaagaaagca gggaataaat ttgactgaag aatctaagca
    10201 aagagttatt caagaatatg ttcctggaaa acaggttaca ttagcacata tcatagctaa
    10261 ccctaatgaa gacatatata agaagttagg attagtactt gataaaaaag atgcaatagg
    10321 aatacttaca ataacaccaa gtgaagcgtc aataatagca gcagatgttg ctacaaaggc
    10381 ttcaaatgta tctttaggtt ttatagatag atttagtggt tcagtagtaa tatcaggtga
    10441 tgtaagttct gtagaatcag cgttaaatga tgttttagaa gtcttaggaa atatgttaaa
    10501 cttctcatct acaaaaatca caaggacata ataatacaat gaagaatata atatttatgg
    10561 gaaagacagg tagtggtaaa actaccttat gtcaaaaact agaccagtta gaattaaagt
    10621 ataaaaaaac tcaatcagtg gaactttata ataatgcaat agacactcct ggtgagtata
    10681 tggaaaatag aaacctatat aatgccttaa taacaacatc agcagatgct aaaattatag
    10741 caatagtgta tgatgccaca caagaagaaa attatatagc accaggtttt gccagtatgt
    10801 tttgcaaaga cgtaatagga attataacta aaataaataa agctactgaa aacgaagtca
    10861 atatagctta tgaaagacta tcactagcag gagcaagtca aatctttaaa atagacacag
    10921 ttgataatat tggacttgaa aaattattta aatatctaga aaaatataaa aatatagatg
    10981 aagtttaagg ggaaatattt ttttattcaa aaatattatt aaagtatgat aaaataaaaa
    11041 aatgtataaa ctattttaag aagatttaat ctttaagcga ggtaggaaca tggggaaaaa
    11101 aatactattg gttgatgatg aaccactgtt aaggatggat acaaaagata tattagaaag
    11161 tcatggctat gaaataatag gcgaagcaag tgatggattt gaagctgttg aaatgtgtaa
    11221 aaaacacaaa cctgatttag ttataatgga tatagagatg ccaatacttg atggtataaa
    11281 ggcaggcaaa ataatatgta aagaaaatct agctggtgga gtacttttat taacttcatt
    11341 tgaagataaa gaatacgtag aaaaggctaa aagtataggt gcttatggat atttagtaaa
    11401 aacagcaagt gaaaaatcac ttatcccaac catagaaatg tgtttaaata aggtaaatga
    11461 atttgaaaaa atgaaaaaag atttagaaaa agtaaattct aaattgaatg aaagaaaatt
    11521 agtagaaaga gcaaaaggta tacttataag agagtttaag atttctgagg atgaagcata
    11581 cactagaata agaaaattaa gtatggataa aagaactacc atgatggaaa ttgccaaaat
    11641 gattataata ggatacgatg actaatacga taaaaaaaat atcaactgca caaacatact
    11701 taaataataa cgaaattgaa aaaattatag aagtatcaaa atccttagat ttaatggctt
    11761 ctttttatga agctgatgtt tttatagatg tactaagtaa atttgatgat gaagcaattg
    11821 ttgtggcaca tggtagacct aaagaaaagt caatgtactg tgaaaatgtt ataggtaaaa
    11881 aggctttaat tgaaaatgaa ccaggagtta taaagtgctt aaaaacagga gaaagagtaa
    11941 gagatattaa agctttaaca caggaatata aactggtcaa acaaaatatt cagccaataa
    12001 cactagatga caaagtttta gcagtactaa tagttgaaaa agatataagt agtgaagtta
    12061 agaatgagtt taatgctagt gaagacgaag aaaataaaaa tttacatcag tttataaaac
    12121 ttataggaaa taatgacttt ttagttgata atttaaattc agccatatta atatttgata
    12181 aaaatggaaa attaaaaatt aaaaatcgta ttgcaactga gatatacaaa aatcttgggt
    12241 ttggatatga tatacaagat atgcattaca atgatttaga tatagaaacc aacacctttg
    12301 aaaatatatt aatggatgaa aattatgatg agacaaatga agtttcaata ggtaatatgt
    12361 tttttaaaat aaagaccata tacatcaaag atgatgaatt taaggtttgc aaaatagtac
    12421 aagatataag tgatttaaag agaaaagaag aagaattagt tttgaaaaca gtggctataa
    12481 gagaagctca tcatagagta aaaaataatc ttcatacagt aatatctata ataaaaaaac
    12541 aaagtagatt atctcaaaat gatgaagtaa agcagtgttt agataacata ataaataggg
    12601 tatttgcaat actttcgact cattatttac tatctaaaga agttgataat aatatatcta
    12661 tacgagaagg tatcaattta ttagtgtcaa atattcaagg tggctattta tttagtaagg
    12721 atatagatat acgtataact ggtgaagatt ttaaaattag tggagaaaaa gcaacagcaa
    12781 tacttttggt tataaatgaa atactacaaa attgttatga ccatgcattt tcggatagag
    12841 aacatggtac tatacaaata ttaataaata aagataacga ctatagaaat attgctatta
    12901 tagatgatgg aattggattt gatagtaata atataaataa aaatagctta gggacatata
    12961 taatagatag ttatataaca cagatgttaa aaggaaatat agagagaaaa agtagtgaga
    13021 atggtacaga agtattaatt actataccta cacaaattaa tatttaaata ataactcatc
    13081 tacaaagtag tagttttaat tgagcaaaga ggcttaaggt tattaataga ttaagttaat
    13141 tgaatgtatt tataaaaatt ataagtatat attcaattta acaggtattt attataactt
    13201 taagcctctt tgcttgttta agacatactt aaattttagg aggtgagaaa atgagagaag
    13261 agttattaag tgttggtatt gacattggaa caagtactac tcagttaatt ttttctaaat
    13321 taatagtaga aaatactgaa tcaaattttt cggtacctag aataagtata gtagacaaag
    13381 aaattattta taaaagcaaa gtttatttca cccctcttat ttcaaataat gaaataaatg
    13441 gtcaacaaat aaaagatata gttgaaaatg aatataaaaa agcaaatata tctaaagaag
    13501 atatacatac aggagcagta ataataactg gtgaaacagc tagaaaagaa aatgcaaatg
    13561 atgtacttca tactttgagt ggatttgctg gggacttcgt tgttgcaaca gcaggacctg
    13621 atttagaaag tataatatca ggaaaaggag ctggagctca tatttattca aaagaacatt
    13681 caactacaat tgtaaatata gacataggtg ggggaactag taacatagcc tcatttaaaa
    13741 ggggagaagt aaccgatact ggttgtttgg atataggtgg aaggcttgta aagatagata
    13801 aaataagtaa aaaaataact tatatatcac ctaaaataga taaaatcata aaagataata
    13861 atttaaatct tcaaataggc acaatggcta ctgtagaaaa tacaaagcca atagtggata
    13921 taatggttga cttattaatg gaaagcatag gattaaagaa acagacacct ttgtttgatt
    13981 ttataataac caataaatca ataagtatag atgaaaatat taaaaatgtt tcattctctg
    14041 gtggagtagc tgattatatt tactatgatg gagaaataaa agattatttt gaatatggtg
    14101 acttgggaat tttacttggg caagcaataa aaaattgtga ataccttaaa aaagtaaatg
    14161 tagttaaatc tatggaaaca ataagagcca cagtggttgg agcaggttct catactactg
    14221 aagtaagtgg aagtacaata acttacacta gcgaaaagtt tccacttaag aacttgccag
    14281 ttttaaaatt atcaattgat gaagaaacag gtacttcaaa acaaatcagt gaagctataa
    14341 aaaataaact taattggttt aaactagaaa atgatttaca gaaagttgct atagccatga
    14401 taggaaagaa aaatccaacc tttttagata tacaagagta tgctaaaggg tttgtagatg
    14461 gaatgcaaca aatcatagaa aatgatttac cttttatagt aattgttgaa aatgatatgg
    14521 caaaagtgtt aggtcaagca atatatgcag tattaaatta tgaaaaagaa attgtttgta
    14581 tagacagtgt caaggttgaa aatggagact atatcgacat tggaaaacct atagttgagg
    14641 gtaaagtttt acctgtggta ataaaaacat tagtttttaa ttaatagaag gaggtaagta
    14701 aatgatttta aatacaaaat tatttggacg tacttatcag tttaaaggct tatatgatgt
    14761 aatggctaaa gctaatgaag aaaaatcagg agataaatta gcaggtcttg cagcagaatc
    14821 agctgaagaa agaatagcag caaaagttgt tttatcacac ataaaattgg aggatataag
    14881 aaataatcct gcagtggcat atgaagaaga tgaagtaaca agaataatac aagatgctgt
    14941 aaatgaaaaa gtttatgaag aaataaaaaa ttggacagtc tctgaactta gagaatggct
    15001 attggattca aatactacaa gtcttgatat aagaagaata tcaagaggat taacttctga
    15061 aatgatagca gcagttgcaa aattaatgtc aaatatggac ttagtttatg cagctaaaaa
    15121 gataaaggtt actgctcact gtaatacaac tataggagaa caaggaacat tatcagcaag
    15181 acttcaacct aatcatccaa cagacgaccc agatggaata cttgcatcac ttcttgaagg
    15241 tttaactttt ggtataggag atgcagtact tggattaaat ccagttgatg actctgttga
    15301 gagtgttact aaagtattaa aaagatttga agaagtaaaa caaaaatatc aaataccaac
    15361 tcaaacatgt gtattggcac acgttactac acaaatggaa gcaataagaa atggtgctcc
    15421 tgcagattta atattccaat ctatagcagg ttctgaaaaa ggaaatgaag catttggatt
    15481 taatggcgac actatagaag aagctagaca gttagcttta aaacacggta cagctacagg
    15541 acctaacgtt atgtattttg aaactggaca aggttcagaa ttatcttcag aagcacatca
    15601 tggaatagac caagttacta tggaagctag atgctatgga tttgctaaaa agtatgaacc
    15661 attcttagta aatacagttg ttgggtttat aggacctgag tacttatatg atgctagaga
    15721 agttgtaaga gcaggacttg aagaccactt tatgggtaaa ctacatggtt taccaatggg
    15781 tgttgatgtt tgttacacta accatatgaa ggctgaccaa aatgatatgg aaaacttagc
    15841 catactatta acaacagcag gatgtacgta ttttatggga atacctcatg gagatgatgt
    15901 tatgcttaac tatcaaacaa caggatacca tgaaacagca tcacttagag aaatgtttgg
    15961 actaacagca ataaaagaat ttgatgcttg gatggaaaag atgggattct ctaaagatgg
    16021 taagttaaca gagttggcgg gagacgcatc tgtattatta ggataggagg tatttaatat
    16081 gaatgagaag gatttaaaag cattggtaga acaattagtt ggacaaatgg ttggagaatt
    16141 agatactaat gttgtgtctg agactgttaa aaaggcaact gaagttgtag tagacaacaa
    16201 tgcttgtata gatgatataa cagaagttga tataagaaag caattactag taaaaaatcc
    16261 taaggatgca gaagcttatt tagatatgaa agcaaaaaca cctgcaagat taggtatagg
    16321 aagagctggt actagatata aaacagaaac agttttaaga tttagagcag accatgctgc
    16381 tgcacaagat gctgtattct cttatgtaga tgaagaattt ataaaagaaa ataatatgtt
    16441 tgcagtggaa actttatgta aagataaaga tgaatactta acaagaccag atttgggaag
    16501 aaaattttct ccagaaacta taaataatat aaaatctaaa tttggtacaa atcaaaaggt
    16561 tttaatatta gttggagatg ggcttagctc agctgcaata gaggcaaatt taaaagactg
    16621 tgtgccagct ataaaacagg gtctaaaaat gtatggtata gattcaagtg aaattttatt
    16681 tgttaaacat tgtagagttg gtgctatgga ccacttaggt gaagaattag gttgtgaagt
    16741 tatatgtatg ttggttggag aaagaccagg attagttact gctgaatcaa tgtcagcata
    16801 tatagcttat aagccatata taggaatggc agaagcaaaa agaacagtta tatcaaacat
    16861 tcacaaaggt ggaacaactg cagttgaagc aggtgctcat atagctgaac ttataaaaac
    16921 tatgttagat aaaaaagctt caggaataga ccttaaataa agtcgaggga gtgtagaata
    16981 tgaaaaatga tgtaattcgt cctaatatac taggaattaa aataatttca aatataagtc
    17041 cagaaatggc acaaaaacta gaattaaaat cacatcacaa aagcttaggt ttaataactg
    17101 cagactgtga tgatgttacg tatacagctc ttgatgaagc aactaaagct tcagaagttg
    17161 atgttgtata tgcaaaatca atgtatgcag gtgctgcaaa tgcttcaaca aaacttgcag
    17221 gtgaagtatt aggaataata gcaggtccaa gcccagcaga agtaagaagt ggtctaaatg
    17281 cagtagttga ttttctagag tatggagcaa cttttataag tgcaaatgat gatgattcaa
    17341 tagcatacta tgctcactgc gtatcaagaa caggtacata cctttcagag gtagcaggaa
    17401 taagagaagg tgaagcatta gcttatttag tagcaccacc ccttgaagca atgtatgcac
    17461 tagatgcagc aatgaaagct gcagatgtta agatgtgtga attatttgca cctccaactg
    17521 aaacaaactt tggtggagca ttacttacag gttctcaatc ggcttgtaaa gcagcatgtg
    17581 atgcatttgc agaagcagta aaatcagttg cagacaatcc aacaggattt taaggatagt
    17641 tagatggatg ctataggctt aatagaagta ataggatatg ttgctgcaat agaagcttct
    17701 gatgcttgtt taaaatctgc aaatgttaat attgtaagag ttgataaggt tggggcaggt
    17761 attgttactt taacaatatg tggagatgtc ggtgctgtaa aagctgcttt agaagcaggt
    17821 gaaatagcag cttccagagt tggtacatta agaacatcac atattatacc gagaatccat
    17881 aatgaagtaa caaatgcttt attcaaaact aaagaactta aagtctgtga agtttcagaa
    17941 gataaagaaa aaaactttga gattacattg gaaatagctg ataatgtatc gaaaaattta
    18001 tcagaaaaag aaaatgtaat tttagatgtc aatgaaaaca gtggagatac tgaaaattta
    18061 tatagtgata tagataaaac aaacaaaaaa attgaaacag ttaatgatag tttaacagaa
    18121 gctaatgagg aaaaaataga aaacactaat gataaagaag tattggaaca agttaaaata
    18181 gaaaattccg attttgatag agatgaccta tcaaagaaca gtgtaaaaaa acttaaagct
    18241 atggctaaga aattagattc ttcaataact tataaagact taaatgttct taaaaaagaa
    18301 gaaataataa acttagttaa aaagcttagc agaagggata gatagttatg acacttttag
    18361 ataaagattt agtatctata caagaagtaa gaactcttgt aagaagatct aaagcggctc
    18421 aagagaaact ttctaaaatg agtcaagagc aaatagataa aatagtaaaa gctgttgtag
    18481 atgcagcatt taataatgct actaaattgg ctaaaatggc aaatgaagaa actggatttg
    18541 gaaaatggga agataaagta attaaaaata cttttgcatc tatgggagtt tatgaaactt
    18601 taaagaacac aaaaactatt ggaataattg gtgaagataa agaagccaat acgatagata
    18661 tagctacacc agttggagtt gttgcaggtc ttataccttc aacaaaccca acatcaacag
    18721 taatatacaa aactataata tctctaaaag caggaaatac tatagttttc tctccacatc
    18781 caaatgcaaa aaactgcata cttgaaacag ttaatataat aagtgaggct gctataaagg
    18841 ctggagctcc agaggattca atattatgta taactaatcc aagtatagtt ggaaccaatg
    18901 aattgatgaa acataaagat acaaacttaa tactagcaac tggaggagaa gcaatggtta
    18961 gagctgctta ctcttcagga acaccagcta ttggagttgg accaggaaat ggaccagcat
    19021 ttatagataa atcagcaaat gttaaattag caatcaaaag aataatagat tctaaaactt
    19081 ttgataatgg tgttatatgt gcatcagaac aatctatagt aatagaaaaa tctatggaag
    19141 aaactgtttt aaaagagctt aaaaatcaag gtgcatatgt tttaaatgaa gaggaaagtg
    19201 aaagattagc aaaattcata ttaagagcta atggtactat gaatccacaa atagttggta
    19261 aaagtgttga ggtaatagca aatttagcag acttaacaaa tgtacctaaa aatacaaaag
    19321 ttctagttgc aagagaaaat aaagttggtc acaatgtagc ctattcaaga gaaaaactta
    19381 caccaatact agcgttctat gttgaagaaa atgtagaagc tattatgaac agatgtagag
    19441 aaatattgtt aaatgaaggt gcaggtcata cattctcaat gcatgtaaat gatgaagaat
    19501 tggtaaaaag atttgccctt aatatgccag tatcaagaat acttgtgaat actccttcag
    19561 cacttggagg aataggtgca tcaacaaacc ttgtaccagc actaacactt ggttgtggtg
    19621 caataggtgg aagttcaact tcaaacaata taggaccact tgatttaata aatgttaaaa
    19681 gagtagctta tggaatcaaa gaaatagaag aacttggaag agataaatct caagttgaaa
    19741 aatcaatgtt tgactcaatg gataaagaag aattaataaa tcttcttgtt caaaaactag
    19801 tcaaagaact agcataacta aaataaacaa tgaaacttat ggctatcgct ataaatttct
    19861 aaaaatataa actataaaaa actataaaat taaatttttg gaggataaga ttatggcaag
    19921 tgcaaacgca ttaggaatga tagaaactaa aggattagta ggagcaatag aagcagcaga
    19981 tgcaatggtt aaagctgcaa atgtacaatt agtaggaaaa gagcaagtag gtggaggatt
    20041 agttactgta atggtaagag gagatgttgg agctgttaaa gctgctacag atgcaggagc
    20101 tgcagctgcc gagagagttg gagaactaat atcagttcat gttataccaa gaccacactt
    20161 tgaagtagat gctatattac caaaggtatc agctgagtaa tataagaata attataaaat
    20221 ttaaattttg attgaaaaag aggctatctc aaaaatgagt cttactaata aactcaatgt
    20281 attttgaggt agtctttttt atacatctaa taggagatgt gataaaatgg gtgttttaac
    20341 agaaaacgaa gtaaaaagaa aaattggaaa aagcaaaaat aatataactg aattttatat
    20401 agaaaaaggt caaataataa ctccttctgc aaaatcttat ttagctgaga gaagtattga
    20461 gcttaaatat gttgataaac tttcagatgt aaacaatgaa cctaaagaag ttgtaaaaga
    20521 agtagttaaa gagaaaaaat ataaatatac tactgtattt ggcgccaaat tggatgaaaa
    20581 accagaacat atgactcaat taaatggaaa tcttttagtt tttaaagacc ataaaagaat
    20641 aatattgaga ggaaaaatag attctcttga atcagaaata ctaaaggtac agatactttg
    20701 tcaaaaacta gatatgccaa agcttgttaa ggaattgcaa gaagtattag actttgtaag
    20761 aaatataatg agatgtgaag ttttagatga aaagctaggg gactttaaac ttttaggatt
    20821 aactcctcaa gaacttagag aacaatctca ctatcctaaa aaatactttg gtataggaca
    20881 tgagttccca agttatgaaa tgggagaagt agtagtagct ataaatagta taagaagtaa
    20941 tacacgagag gttgaacttg cagcctatga agcatttaag ggtgagtatg gaaatgttca
    21001 cagagaagat ttaataaagg cacttaatag attatcgtca gtattttgga taatgatata
    21061 taaggttaga actaataagt ataagtagtt ggaggacata atggagaatc tattaaatga
    21121 aatagtggaa gaagtaataa ctagagttaa aaaagaagca tttatagaag ttgaagcatc
    21181 aggaagacac gttcacttaa gtagagaaga tgtcgataaa ttatttggag aaggatatac
    21241 tcttacaaaa ctaaaagacc tatctcaacc aggtcaatat gcatgtaagg aaagagttac
    21301 aataactggt cctaaaggaa gtataaaaaa tgtagttgta cttggaccat gtagaaatga
    21361 aactcaggta gaaatatctt taacagatgg ttcaactctt ggactaaaag ctcctataaa
    21421 acaaagtgga gacttagaag gtactttaag tattaaaata tcaacacaat atggtgaagt
    21481 tgaacttgat aaggggctaa tggttgctaa aagacatata cacatgactc ctaaagatgc
    21541 tgaaaaattc aatgtatgtg ataaagagat agttgaagct aaggtgatgg gtcaaagacc
    21601 tttaacattt gatgatgtag taataagagt gagtgacagt tttaaaactt atatgcatat
    21661 agactatgat gaagccaatg catgtggtta ttcaaaagga actgttgcta aaataataaa
    21721 gaaagcataa atttaaccta ctatataaat tacctctagg gaggatttaa tatgaattat
    21781 gataaccttg tagatttaat aacggaagaa atctataaaa aaataaatag taatgaaata
    21841 aaaatatcta ataaacctaa agctgtgatt gtatttgaac aagataacaa taaatttaac
    21901 ttattaaaag atgaatttga aatagtagaa tttgataaaa gtataaggga atgtgaaata
    21961 gtgatagttt caagactttg tatgaggggg ctatcgaata tagcacttgg aaattcaaca
    22021 agtgatgaag aaagatttat actaaaaatg attatgaagg gcaaaaaagt atatgtccta
    22081 gatgaaggaa ttgaatacaa aaaatataag gatactgcac caaaagcatt atataagaaa
    22141 tttatgtcat ttgaagatga aatatgtaaa tttggtgtag aaattataaa agacttaaat
    22201 gttataacta aaaataagtt aaatataaag aaagaactag aaagtactag aggttctaaa
    22261 aaagaagata caaaagtttt agataaagat gttttaaatt taaccagtgt agaaagtgta
    22321 aaaatagata atgaatttag tttggattta aggaataaaa aacttatatc ggaagctgac
    22381 ttaagaaaac caactataaa tggagttaaa aacatattag ttaataaaaa aagtataata
    22441 acaccattag ctgtagattt tatgagaata caccatctca aactaaagaa actgtaagga
    22501 ggtaatttta tggatatagg aaaagttgta ggtaatgttt gggctacaag aaaagatgaa
    22561 aaattatgtg gccaaaaact tttagttgta aaaattttaa aaactaaaga cacatacaag
    22621 gaaggcttca tggttgcagc cgataatgca ggagcaggaa atggagactt agttcttata
    22681 tccaaaggtt cctcagctag agagtcgatt gaaaaatctc atgttccagt agatgcaact
    22741 atagttggag tagtcgattc gtttgaggtg tttgatgaat aaaagtatag gagccataga
    22801 gtttaaaagc attgctaaag gtatagaagt atccaatgaa atggtaaaga aatcttcagt
    22861 tgatgtattg tacttaaaaa gcatttgccc aggtaaattt ctaataatag taggtggaga
    22921 aacttcttat ataaatgaat gtgtagatta tggaataaaa cttggagaag gatatattgt
    22981 agataacttc gtaataaatg caatttcaca agaaatatta gatggattta aaaataagta
    23041 tcaaaagcta gatagtatag tctctatagg cgttgttgaa agtagtaaag tatgcgctgg
    23101 aataaaaatg cttgataaga ctttaaaatc tggcgactta gtattagtaa aacttcaatt
    23161 atcttttgct ataggtggca aattagtata tatagtagca ggagatttaa gtagtttaga
    23221 atatgcatta aaagaaagtg aaaatgtagt aagagaaaaa gaagtaatat ataagactgt
    23281 aataccatca gtagacagtc aaataataaa aagtctaata aaataatggg gggaattatg
    23341 agtataaacg aaattataat ctatgtaatg gtagtcttca tggtacttgg agctatagat
    23401 aaatgtatag gtaacaaatt tggtcttgga gaacaatttg aagaaggtat aatggcaatg
    23461 gggtcacttg cagttgcaat ggttggtgtt atatgtttag ctccagttct tgctgatgta
    23521 ttaagaccaa ttgtagtacc agtatttaat atacttggag ctgacccagc tatgtttgct
    23581 ggaagtttat tagctaatga tatgggtggt gcgccacttg cacttgaact tgcgaaagac
    23641 cctaatgctg ggttatttgg tggattaata gtaggggcta tgatgggacc tacaatagta
    23701 tttataatac cagttgcgct tggaataatt gaaaaagaag accaaaaatt cttagcaaca
    23761 ggaatacttg caggtataat aacaatacct attggagcat tcgttggtgg attagttgca
    23821 ggattcgagg taatgatggt tcttagaaac ttagtgccaa taataatatt tgcagtagtt
    23881 atagcacttg gattattaaa attcgaaaat gctatgataa aaggattcac atactttgga
    23941 aaaggtgtag taatagttat aactttagga cttgctgctg ccatagttga agctttaaca
    24001 ggaatagttg taatacctgg aatgaaacca atcagtgaag gtatagaaat agttggagat
    24061 atagcaatag ttttagcagg agcattccca ttagtgtttg ttataacaaa ggtatttaat
    24121 aaaccattaa tggctttagg aaaagttctt ggaatgaatg atgtatcagc agcaggcctt
    24181 gttgcaagtt tagctaactg tataccaatg tttggtatga tgaaagatat ggacaataga
    24241 ggaaaaataa taaatgtagc attctctgta tcagcagcat tcgtatttgg agaccactta
    24301 ggatttacgg caggatttaa ttctaatatg ataacaccaa tgatagttgc taaattaatt
    24361 ggtggtataa cagcagtatt gttagctatg gttatcgcaa ataagacact aaagaaggag
    24421 aatgtataag atggatatat caaatataga taaaaattta attgaaacat tagtaagaca
    24481 aataatagaa gaaaaaataa gtggaactaa agacacagta gattttgtta gaaataaaga
    24541 cattagtgga ataacttcta taaagttacc aactgtaaaa gttagtgaat ctgatagatt
    24601 agatacagga aatccaagtg atgtagttta cacaaaagat ttatttacat tagaggaaag
    24661 cccaagatta ggttgtggta tgatggaaat gaaagaaaca acttttgatt ggactctaaa
    24721 ctatgatgaa atagattatg taatagatgg aactttagat ataataatag atggaagaaa
    24781 ggtttctgct tcttcaggtg aattaatatt cataccaaaa ggaagtaaga tacaattttc
    24841 tgtacctgat tatgctagat ttatatatgt aacatatccg gcagattggg catctcaaaa
    24901 ttaataaaaa tcaagttaag ttaataataa tcaaataaat aatttaaaat acaaactctt
    24961 aaataagcac acatatttaa aaaagctatg aattaaaatt catagctttt tttataaata
    25021 atgttatatt ttagacgtat tttttctata tttactggga gacatattat attttttatt
    25081 aaataatcta ataaaatgct ctacatttgg ataaccaata ctattttact gataatcttt
    25141 tccttatcac taatcttaca ttttaaaata ttatttttac tcgtaatatt atcataagaa
    25201 tttgtttctt atttaaaact aattagaatt ataaagttta ttgccatgtt attaataaaa
    25261 taaatccagt taaatcgagt gctagttaaa gtaataagaa acttttacaa tggtttcctt
    25321 tatcgattga aataaaagtt aatatggtat aatatctaaa gagagaatct tatcaattag
    25381 aatatgcata gaaacaagtg gcttaaaagg agacgttata tggaagagat agtaaagaag
    25441 gaacaagcaa gtatgaatga tatttttttg tatcttaaag ctaaatcaaa ctcattatat
    25501 aaatttgtaa tattatataa tgagtttatc aataaaccta aagattatgg aactggggaa
    25561 cttataaaca tggttgaagt acatatgcta acagcgattg aagaaaatcc aggaataagt
    25621 ccaactcagt tagctaaaat atggaacaga actaaaggtg caatatctca aactatatct
    25681 aaattggaga aaaagggtta tataactaaa gaaaagaaag aaggaaatgc aaaaactata
    25741 ttactatatc caaccacatc aggagtagag ttaagtaagg cacataaact atatgacacc
    25801 atagatgtta caagaacatt tgaatactta atcaaggagt gtacattaga ggagatagat
    25861 agtttttata aagtaattga tttgtttatt aatttattag aagaatctcc gcaggaaaat
    25921 aatgattctg aaaaagtgta gctgagattg aagttgaata aagagaaata gatattatag
    25981 aagtagtact taagtacaca ttatataaaa atataatagg tataggatta aaaagtttag
    26041 tggtttaaag tttaaccact aaactttttt aatgtctata atctactatt atttaattta
    26101 ctaaaaataa aaaaactcat tatattaaga taaaaataga aaaataacta gaaaaatact
    26161 ataatatatc agcttaatac agaaaaaagt taaaagattt gagaaaaata aaaatgaaaa
    26221 cgttttatat tgacatagag aaaaagtagt gataccattt aaatatagtt tagtagctaa
    26281 actatattta aattataata actattttag ggggatgtta tgaatttaaa acaattaagt
    26341 gaaaaatacg aagaatatgt aattcaaatg agaagagaat ttcataagta tccagaatta
    26401 tcttttaaag aaataagaac aacccaaaga ataagggaag aattacaaaa aataggggtc
    26461 ccttttgtat ctattgaacc aaatatagta atagctacta tacaaggcaa aaatgaaggt
    26521 aagacaattg caattagagg agatatagat gcgcttccaa tgcaagaaga ttcagatgtt
    26581 gaatacaaat cagaatatga tggaataatg cattcttgtg gacatgatgc tcatggagct
    26641 atgttactag gacttgcaca tatgctaaat gatataagaa aagatttaaa aggtagagta
    26701 ttattagttt ttcaagcagc tgaagaagtt ggtggtggac acaaggagat aatacagtac
    26761 tttaaggaaa atggaggacc agatagatta atagctactc atgtttggtc cgatattgaa
    26821 gctggtaaaa tttctgttga accaggacct cgtatggctg gtgggtctgg ttggagaata
    26881 gacataacag gtagaggagg tcatggttct agaccagatc aaagcataga tcctataaag
    26941 ccagcttgtg atatagtttt aaaagtatct tctataccag ttaatcatat aagtgtacta
    27001 gaacaatgtg ttgtacatgc atgtgcaata catggaggaa ctacaatagg aaatgttatt
    27061 ccaaacaatg cagaggtaat aggtggatat agatatttta ctgaagaatc aggcaaaaaa
    27121 gtgtttgaca ttataaagca aatgagtaat ggtgttggac aagtttatgg agtggatgtg
    27181 aaggttactc atactggagg cataggacct gttatcaatg atgaagaagc agttaagatg
    27241 gctaaagaaa tagtttctaa tatagatgga ttggagttag attcttatga gccaatatgt
    27301 gcatcagatt gttatggtga aatattaaaa gagtattctg gcttttattg ttatctaggg
    27361 gtaggtaaca aagaaaaagg aataatatat gcacaacatc atcctaagta caatatagat
    27421 gaagatacat taaagttagg ttgcgaattt atggctaaat atgcagttga atttttaaat
    27481 aaaaataata actaaaataa atcgaatttt ataaatgggg ggatgaaaat gcaaggtgca
    27541 ttaaaggaaa ataagaaaaa aagtggtgga ggatttttag gatggattga aaaagttggg
    27601 aataaaatgc cacatcctct agcattattt acatatatta cattgatagt agtagcatta
    27661 tctgcaatag caagcttttt aggtttttca gcaacaagtc ctgctacagg aaagttaata
    27721 aaagttatga acttaataag tgcaaaaggt ttagtactat ttatgcaaga gtttgttaag
    27781 aacttccaaa acttccctgt gcttggagta gttttagtta tggcagttgc cacaggagtt
    27841 tgtgaaaaga caggattttt ttcaactgcc ataaaaatga gtttatcaaa agttaagggg
    27901 aatgcggttg tatttataat agcttttata ggagtatttg ctaatcaagc tggtgatgct
    27961 gcttttgtat tagtaccaac tcttgcagga gcaatatttt atggattaaa tagaaatcca
    28021 ttagctggta tattctgtgg atttgcatca gttggtggtg gatttgcaac agctgtaatt
    28081 cctgggggat gggacgttac gctaacgcca ataactgtat cagctgctca aactattcaa
    28141 cctgcatttg atatgacatt attagctagt tattatgcac tatttgtatc tgcgtttata
    28201 gtagctacag tatcaacaat agtaacggtt aaatttatag aacctaaatt aggtgagtat
    28261 actggtaaac cagaaggtat agatgataat caaggttttg aggtcacaaa agaacaagca
    28321 aaagcagcaa agttagcagg ttttacagtt ttagcttatg tagcgttatt aattgctttg
    28381 tgtataccag ctaatagttt tttaagaagt ccagaaggtt ctttaatatt tggagcacca
    28441 cttatgtctt gcttacagtt ttttatagta atactattct tcttgccagg gattgtgtat
    28501 ggaatgaggg ttggtaaaat caagactgta aaagacttaa atgatatatt atgtcaatca
    28561 atggcagcaa tggcaccgtt tatcgtactt gcaatagtta taggtcaatt cttaacgcta
    28621 ttctcagtgt ctaatttagc acaggtacta gctataaaag gtggagcatt actcaactca
    28681 ttgccactac caccacaagc tataatactg ctattcttag tactagtagc gtttataaat
    28741 atatttgtta taagcgaaag tacaaaatgg atgatatttg gaccagtatt tgttccaatg
    28801 ttaatgcaat taaacataca tccagcattt actcagtttg tatatagatt aggagattct
    28861 gtaaccaatc atttatcacc attaaatgca ttctttataa tacttttagc aacagtccaa
    28921 aaatacgata aaaatgcagg tatgggaact atattctcag ctatgatacc ttacactata
    28981 ggttactttg tagtacttgc agttttagta gtagtttgga tgacaatagg tataccagta
    29041 ggaataggtg gacaagtttg gttataaaac atatttaata attttgggag gaaagaaaat
    29101 ggaaacaact gaaataagat acaattttga tgaagtaata gatagaagtg gaacaaactg
    29161 tcttaaatat gatcttaaga gtcaatttat gccagaatct ccagaagatg cactaccact
    29221 atgggtagca gatatggatt ttgcatgtgc ccctgagata attaatgcaa tgcatgaaag
    29281 aatagacaga aaaatatttg gatatagctc tcaacaaact gatgattatt atgaagctgt
    29341 atgtggatgg tttaagagaa gatttgattg gaaaatagaa aaagagaata tattctttag
    29401 cccaggggtt gtgcctgcgt taggattttt cacacaaata ttaacacaaa agggtgatgg
    29461 tatcataata gaaaagcctg tatactatcc ttttgaagat aaaataacta acaatgaaag
    29521 aaaagtagtt aatagtcctt taaagtttga agatggtcat tattctatgg attatgatgg
    29581 atttgaagaa ttagctaaag atgaaaataa taaggtgttt atattatgta gtcctcataa
    29641 tccagttggt agagtatgga aaaaagaaga gcttagaaaa atagtagaca tatgtaagaa
    29701 atatgatttg tggataatat ctgatgaaat acattgtgat attattcgta aaggtgaaaa
    29761 gcatatacca ttagaagtag catgtcctga ttataaagat agaataataa cttgtacagc
    29821 tccaagtaag agttttaact tagctggtat gcaattatca aatatagtaa tcaataataa
    29881 ggaattacaa gaaaaatgga tgcttgaaac agattctaaa ttagctatat tcctacctaa
    29941 tccattcgca atagttgcta ctaaagttgc ttataatgat tgtgaagatt ggatgaatca
    30001 agtaaatgag tatatagatg gtaatattaa atatgtagaa gattttgtta atgagtatat
    30061 gcctaaagta aagataataa aatctcaagg aacttactta gtttggttag actttagagg
    30121 gtatggatta gatgcaaaac agcttgaata tgtaatgctt aacaaggcga aggtattgct
    30181 agatgaagga tacatattcg gagaagaagg agcaggattt gaaagaataa atgttgcttc
    30241 acctagaaca attatagaag agtgtatgaa tagaataaaa tgtgcatttg aaggattata
    30301 atagtaatat ctaaataata tatttgtgta ttttaaaaaa agactatgct aaaaaaatat
    30361 ttcaaagcat agtcttttaa agttttatga tgagtttaaa aaatttcaaa acgttactat
    30421 tcacttatat gtttatatta gaaataattc cacaatatac tcattttcta aagttgcact
    30481 tttatacacc ttgcttcacc aatatcatgt gtaaccaaaa tagtagactt attctcattc
    30541 ttaataatac tataaacatc atcacaaact aataatctag tctgataatc aagagctgaa
    30601 aaaggttcat ctaaaagtag aatatctgga tttacagaaa gtgttctaat aagcgcaact
    30661 ctttgtctca tacctccaga taattctttt ggatacatac ttctaaaatc ccataatcca
    30721 taagtcttta aaaggctttc aactctatct aaagattttt tatctttttt gccttgaatt
    30781 tccaatccaa tagttatatt atccattata tttctccatt caagcaaatt atctttttga
    30841 aacatatatc caatatttcc agtaatcttt atatcaccac tagtcggttt taaaagatta
    30901 gtaagaatat ttaatattgt agatttacca cttccagaag gaccaagcaa agttaatatt
    30961 tctccttctt tcaagttaaa attgacatcc tttaatactt caagctcgcc ttccttagtg
    31021 tagaagttca tatttatatt tttaacttct actatgttgt cattcattat gccaccccct
    31081 ataactttta gctcgtatat attatgttat taacaatatg acctatttgt accatttttc
    31141 ataaatataa tataaatatt ttgtttattt acgtattttc ttagtaactt gtacgtataa
    31201 attatagata aataaattat aaggtagggg ataaatttga gtaacataat aacgaattta
    31261 atagagtcaa tatttactaa tccaataact atattgtttt tacttgcaat aactgtgtat
    31321 tctgttttta aaataataga aaataacaga gtatattcat ttgtaagttc aaaattagac
    31381 gaaatcaata gagactataa gacaagtgag ttttataaaa aggtaaggga tgactactat
    31441 acatatagta aagaaaatcc ttatgcagac gtaaatataa cttcatttat agaggaagtt
    31501 gtatctgatt taaagcataa taatttgcca ttgttagaaa aaattagaag tataaaaaat
    31561 tcatcttcaa taagtatatt acttggggtt ttaggtacgt ttgttggtct ttctacaatg
    31621 cttttatgtg ttgatactaa agacattata aattcacttc cttcaactat tagtagtatg
    31681 caaactgcat ttacaactag tatatttgga gttgtatttt ctctaattat aggttacttt
    31741 actaagataa aagattgtga acatgttttg atacaaataa tgttaaaatc tgaaaattta
    31801 ctaacatctg aaataactca ttttaagtca gaaagaatgg atttaaaagt agaagaggta
    31861 aaaaatacaa taaaacaaat aagtaagtct atagaagcta ttgaaaaatt tgataaaata
    31921 tctaaagatt taaatgactt taatgatgaa tttatcagtg gtatagaagc tttaaaaagc
    31981 cttttagaag gttctcaaag ttctattaag acatttgacc agagcgtaag aaaattagat
    32041 aaacagttta atattttaaa tataaaattt gtaaagcttt ttgataaata tgataatcaa
    32101 gataatataa ataaagagat tttatttgat ataaaagaat cttcaaaaaa tatatacaat
    32161 gccactgaaa gccaattcaa aattagagat tatataaaaa atataaatgc aggatttgct
    32221 ctatatgaaa gaagtgctca agatttatta actaaattaa tgacccatga aaataaaata
    32281 tctcaaaatc aaaaaatcct tttagatgaa aagtttacct tagatgactc aataaaaaat
    32341 ctctcaagta ttattgaaaa cttttctaat gacctacaag ttaaactgga tatgatgttt
    32401 gaaaattctt tagatattca agataagtta gatgttatgt ttaataactc ttttatgaat
    32461 gatgaagttc ctcttgatag tgaagaatta tttaaggatg atgttaataa tgtatttaat
    32521 ccttttagtg aagaaattta tgagatagag gataaagaaa taaaggtcat aggtgaggat
    32581 gagttaaatg aataataaat atagaagaac tgttaacaga gaatttgaaa agagtagctt
    32641 ttggccaaca tttacagatt tattatctac tgtattgatg gttgtaattc ttatcttatt
    32701 tagctcagaa agtatttcag gttctgttga acaagattta gctaagaatg tcaatgcttc
    32761 tgttgaagaa acttttaaaa aaagtggaat acctgtgaag gtagataaat ctaatgggca
    32821 agtaactttt ggtgaaaaaa ccatgtttga tgtagatagt gatgttttaa aaccagaggc
    32881 taaagaaatg ctaaaaatgt ttgttccaaa gtacatagag actatttata aagattatgg
    32941 tgactatata tccaaaatag ttatagaagg tcatacagat gatgtgggaa gttatatata
    33001 caacttagat ttatcgcaaa gaagagcata tagcgttgct aaatttatag tgggagatga
    33061 aataggtgac tataaataca aagataaagt gactaagcat attattgcaa taggaaggtc
    33121 aaaagctgaa ctcatcaaaa atggtgacaa tagcgtgaat agagatgcat ctagaagagt
    33181 agaactaaaa tacgaaataa atattaatca aaataaataa ttaaattttt ataaaaaaaa
    33241 agaaggcagt tggtgtgagc tttaagcctt ctttaaggaa aaagtttatt tatttttgtt
    33301 gatacttaac atattatagt ttttagaagc agtttgcaat atattaaacg taaatggtcg
    33361 tttaaaatgc ataactggat actactgatg taaaatattt cattttatat aatataaaaa
    33421 ttatacagtg tcaattttct atattattgt actataatct attatttaaa atattatgta
    33481 aaaaaatatc ataaaaacgc atatcatgtt ataattacta gagtattatg aatatggagg
    33541 cgtagtttgt gatagaaata agtataaaaa ataaaaaaaa ttctaaaatt aaaactttga
    33601 tacttttatt gatagtatct atatcgattt atttaactgg ttgtactaca tcagataatg
    33661 gaaataatca atcaaataat aatgattctt tgtctagtag tatatcaagt gataagaatg
    33721 taaaaattca ttttattgac actggaaata gtgatgcaat attgattcaa gatggtaaaa
    33781 cttttacatt gatagatggg ggagataatg atgatgaggg attaatggta gattacctaa
    33841 acaatcaagg tgtaaaagat attaaatatc ttatagctac ccattctcat gcagaccatt
    33901 taggtggact tgattctgtt gtcaaaaact ttaatataga aaatgttttt gtatcgaatg
    33961 gttcagcaga aacaaagagt tatagggact ttataaatgc tttagcaaat aagggtttat
    34021 ccccaagtgt accgcttgaa aataataagt tctatttaga agattcttat tttgaagttc
    34081 taaatacaaa tgggggagat actactaatg aacaatctct agtccttgta tatactaatg
    34141 ggaatgataa agttttattt acaggtgatg ctgaagaagg taccgaaaaa gaaatactac
    34201 ctaagcttga gaaagtagac cttttaaaag tagctcatca tggttctcgt agtagttcat
    34261 ctcaagagtt tttagataaa gtaaatcctg aatatgcggt tcttttagta ggcaagggta
    34321 attcatatgg tcatccacat caggagacaa tgaataaatt aaaaaaaatg ggagtaaaag
    34381 tgcatagaag tgatgagtgt tcagatataa tatttgaatc aacaggtgat ggagtattta
    34441 caagttgtaa agatggaagt tataataaag gcgttagaga agatggaaac tctggaaaat
    34501 caaacagtaa tacaagtaaa aatgattctt ttaaaaataa acaaaataca tccaattcag
    34561 aagaaatagt gtactttact ccaaaaggta agagttatca ctctacaaaa aattgtagtg
    34621 ggctttcaag aagtaaaaaa atattatcag gcacaattgc agaaagtaag aaaaatgacc
    34681 catgtgatat atgttatgga aaataacaaa aaaacaacca atttatctat aaagcttctg
    34741 aactttaaat catttaaaaa ataaaataaa tgcataaaaa aataagctat aatcaataga
    34801 taacacattt tatctatacg aatagcttat ttttttaagt attttttaat agctatttaa
    34861 taactctaaa tacaccagtt acaataccta caatttcaac ttctgagtca ttgagcataa
    34921 ttggttccat aaaatcattt tctggctgaa gtcttattaa atttccttct ttaaaaaacc
    34981 tcttaactgt agcagattca ccatttataa gtgcaactac tatctgagaa tttaaggctg
    35041 tatttttttt gtctactaca acgtaatctt catctaaaat tcctgcatta atcatacttt
    35101 cgccttttac tcttaataca aaattgttac tgccctttac taaactggca gggaatggaa
    35161 tgtattcctc tatgttttgt tgagctaaaa tgggttctcc agctgttatt tgacctacta
    35221 aaggaagctc tattatttct tgattagctc cagaaacatc atttacttta ctacgttcta
    35281 aaacttcaat agctcttggt ttagtagggt cctttcttat gtatcccagt ttttcaagtt
    35341 tatttagatg agagtgcaca gttgaagtag atcttaaccc tacagcagta catatttctc
    35401 ttacagcagg tggataacct tttaatatga tttgagactt tataaattcc aatatcaaga
    35461 cttgcttttc agttagatct aaatacataa catcactcat ttccaaacat attttgtttt
    35521 tatttccata cactttatat ttttaattat aacataatcc atttatatct gcaaacattt
    35581 gttcctgatt tttaatcgtc ctcaatccat tcaaaattct tgactatatc acgttttaca
    35641 tttttcttat gagctgcata aagctgagta gttgtgacat tatcatggtc aagtaagttt
    35701 tgaacatcat atatagaaaa tcctgtttgg attagagaag ttgcagccgt tgctcttaat
    35761 ttatggggac tatatccatt gtctctagta gtatcaagtg gaatagatgt atattttttt
    35821 accagtgttc ttatagcctt tgctgtaatt ctcttatttt gaagagacaa aaataaagca
    35881 tctttttctt catcatttaa tagttcatct cttgttcttt cgttttgcaa ataatctttt
    35941 attacatgtt cacaagtatg atttataggc attaaaactt ctttcccacg ttttctatat
    36001 attttaaatt cacctcttga aaaattaaaa gaggagatat tgagttctct aagctcattt
    36061 aatctaagcc cgtatgtaac aaataatgct agtatagctt tgtcacgtaa tttagttttt
    36121 ctccaatata ccttttcttt ctctgtaagc ccttcacctg tttctactga ttcaagcatc
    36181 ttagcaactt catctatctc aaggcgctta atagcatctg gctgaggttt aggaagtttt
    36241 attggattga atccatcagt tatattatta tctatctgag agtttctgta taagaattta
    36301 aatagagtag agatggatga tttttttctt gctaaagctc tattgttatt ttcaaaaatc
    36361 aatgtgtttt tttctgtatt tttgtaatat ctactgcaat aatcacctaa gaataaattt
    36421 atatctcttg attttattgt attaaaatca tcttctgtaa tatcttttac acaatctgca
    36481 tttgttaatt ctttggtttc aatcaaatat gaacaaaaaa aattaatatc ttctaaataa
    36541 gcaagtcgtg tagaaactgc aacagaacct tttaaatata taaaataatc cttcataaat
    36601 acaggaagtt tattttccaa aagtagacat ttttctatga gttcattttc tttgataaca
    36661 atattatcag gtttatctga tttattatgt acttttataa ttttcttatc attattcaaa
    36721 attaaacctc ctaaaactaa aatataaatc ttttatatta ttttttgata tttataccaa
    36781 gtgagtataa atatttaatt taatcatttt ttacattttt aagagattag cagtgcttta
    36841 gatgaaatca tcactaacta ttccctaaat ccacatttaa agactagttg aatttaagta
    36901 ctctttttta tttctcaata tatttataga aatattttaa aatatattga gaaatttttt
    36961 atgctctact aaaatctttt ttatataata tttttatatg tttctaacga aaccaaatat
    37021 tagtaaaata tgtatttatt taactaaagt ttttaaatgg gctgactaag cttaaaatat
    37081 aggatattat gagagttact attgaaaaaa taaaccctat tgccataaag aaacttataa
    37141 atatgttata cttaactatt aaactggata tattcaagtt atcaaatcca aataagtatg
    37201 taattgaact tattacaaaa ataactataa ctataaagct cagaccattt aagctatttt
    37261 ttaaatcagc actactaagt gacatatgtg tagatataga atacattaaa aacataaata
    37321 taaaatactt caatgaatat acactaggtg ttaacaacat tattcttata aaattggaaa
    37381 tatcacctaa aataatgtgt ataaacccat ttatatttaa attattaatc atacttacat
    37441 ataactttaa atctatattt tgagtcactt tcatataact atctggcagt aatatcttaa
    37501 aaattaaaat aatcattatt gttccaccta taataggtgc aattcctata aagaaatttc
    37561 ctatactttg ataaagatta tcttttttat agctatgact tacatatcct agtataccat
    37621 catttttact ttctattggt ctgaaaaact taactgaatt tattttatgc atgaaaatta
    37681 aacacattat caaatgactc aattcatgaa caaacgttcc tatagctcca gttacaataa
    37741 ttccagtttt tccaaaagat gaaaatataa atttattatt tagattttct gtaatgctaa
    37801 aaatcaatcc aaatacaata aatattccta tgaaacaaaa aatatttatt acacttattt
    37861 ttaaaatttc gattatataa atcataagtt aagtcctcat gtaaaagtat ttaactactc
    37921 tacttcatat ccattacagc ttaaaatttt acaagcattt tctatatctt tttcttttac
    37981 taagatatag tctgtatcat aagtagaaat tgcaaatatg cttattttgt tgtctgctaa
    38041 caaactactt aacttagata aaattcctac aagtgaaaag tctaaaggac ctagtatctt
    38101 aagtattctc cactcctttt ctgacttgac atcagaagga atattattat ttaaacatac
    38161 aacacttaat tcatcatcag ttctagttat agagtaaaac ttctctgtat ctatccatgt
    38221 tggtatttta ctgtcattat ttaatctaca tactgcatac tcttctacca ataattttaa
    38281 tttcataatg tatatttcct ccaatcttat ttgtttactt aagattatac attaaaagtt
    38341 acataaaata aaacatataa agtaaaaaag gttcactata gtgtcctatt tctatagcca
    38401 acctttaaaa cttaattaaa ttctaataaa gagatatatt atctaggttc aattataagt
    38461 ttaatggctg ttttcttatc accttcgatt tctatatcag taaatgcggg aatgcaaact
    38521 aaatccattc cactaggtgc aacaaaacct cttgctattg caattgattt tatcgcttga
    38581 tttagagctc cagctcctat agcttgtatt tctgcaacgc ctcgttctct tagtactcca
    38641 gccaaggctc cagctacaga attaggatta gattttgatg aaacttttag tacctccatt
    38701 tcaacatctc cttgttaatt tgttaaagta tccattacct aaagtactaa atcataattg
    38761 ccatttacta attacaatca tcatttaaag tatactttta taaaaatata cttctataat
    38821 cgttttaaga aaacctttat tttttttaac cattttatta tgaaaaaact acaaatttct
    38881 ttatattcta taagcatttt ccaatatttc taaatttttt atatctttga gctataattt
    38941 cctctttatc catatctttg taatgattta atctttctaa aatataagct tttatttctt
    39001 ttgaaacagc ttctacatct ttttgtgctc ctccaagagg ttcttttata atcttatcta
    39061 ttatttttaa atcatataaa tcattacttg taagcttcat aacatcacaa gcttctttag
    39121 ctttagatga atctttaaat agaatactag aaagtccttc tggagaaatt acagaataaa
    39181 ctgaatgttc taacatacat acatcatttc ctactccgat acctaaagct cctccactac
    39241 caccttcacc aattacaaaa gtgattactg gaacagaaag tttactcatt tcaagtaagt
    39301 ttcttgcaat agcttctcct tgtcctcttt cttctgcttc tagaccacaa aaagctcctg
    39361 atgtatcaat aaacgttatt ataggtctat taaatttttc agcttgtttc ataagtctta
    39421 atgcttttct gtatccttct ggatgaggca ttccaaaatt tctttttata ttttcttttg
    39481 tatctcttcc tttttggtgt ccaactatag taacattaaa ctttcctatc tgaccaattc
    39541 ctccaaccat agaagggtca tctttaaaaa gcctatctcc atgaagttct aaaaaattag
    39601 aacaaatatg ttctatgtat tccaatgtcg taggtctctt tatatctcta cttaatgtta
    39661 ccttttcata tgctgataga tgtgaaaaag catcttcctt aagcttttcc aatttctcat
    39721 taagtgaatt tattttatca cttaaatcta tattatttgc cttagaaata gttattaatt
    39781 gtttaatatc attttctaag acttttattt tttcactatt attttcaatc aaaacagttc
    39841 ctcctttatg ccctatttct tgtgcatagc aagaatttga tataatactt ccttcatttt
    39901 tcttctatct actatcatgt caataaaacc tttttcaagt aaaaactcag aagtttgaaa
    39961 tccttcagga agtttttgat ttattgtttg ctctattact cttggacctg caaaacctat
    40021 caacgtattt ggctcagaaa ttataatatc accaagcata gcaaaactag cagttactcc
    40081 tccagtagta gggtcagtta gaactgatat atatggcaat gatttttctt caagcttaga
    40141 aagtgcttga gaagtctttg ccatctgcat aagagatacc ataccttctt gcattctagc
    40201 tcctcctgaa gcagaacaaa taattatagg taaattattt tcagcagcat actctattga
    40261 ataagttatt ttttccccaa caatagaacc catacttccc atcataaaat caggattcat
    40321 tacacaaata actgttttaa ttccatttat tcttccataa cctgtgacaa cagcttctga
    40381 ctcttttgtt ttttccttat aagagtctac tttttctttg tatttaggaa aatttagtgg
    40441 attttgaaat tctacatcag aattaaactc cataaaagtt cctttatcaa tcaataaatt
    40501 tattcttttt cttgctctta agccataatg tcttgaacat tttggacata caaatgaatt
    40561 ttcttctatg tcctttctaa atacatgact atcacaacct ttgcaatagg tccaaaattt
    40621 atcatctaca ctattctttt taaagttgtc atctaaagaa atcgtaacat acttagattc
    40681 ttttgatgat aaaaattttt ttatcataat ctatttactc cttataatgt agcaaattct
    40741 ttcttcataa agacatcttc tataaatttg gtatgatgag tatcttctct aaactcctca
    40801 cttgttacaa gtgccttttg aaattctaca tttgtattaa taccttctac aataatttcg
    40861 tctagagctc tatatattct acttatacat tcttctctag tttcagccca acatattaac
    40921 ttacctatca tagaatcata taaaggtggt atagtatatc ctgcatatac aaaagtatca
    40981 aatctaacac caaaacctcc aggtaaattt aatgattcta tcttacctgg tgatggagca
    41041 aaattctttg atgaatcttc tgcatttatt ctacattcaa tagcatgacc tctaaaagta
    41101 atatcttctt gtttaaaagg aattttatcc ccattagcta tagatatttg aagttttata
    41161 aggtcaagat ttgttaccat ctctgtaact ggatgttcaa cttgtattct tgtattcatc
    41221 tctataaaat aaaagttttt atctttgtca actataaact caatagtacc tgcaccgata
    41281 taacctactc cttttactat atctactgca attttatgaa gtttttgtct ttcttcatct
    41341 gaaaggtatg gactcaaaga ttcttctatt actttttgat ttcgcctttg catagaacaa
    41401 tctctatcac ctaaatgtat tgcatttaaa tgtttatctc caaatacttg tacttctata
    41461 tgtctaggat tttctataaa cttttccata tataaatcac tattagaaaa tgctgctaga
    41521 gcttctgaac ttgccatatc aaaatttgaa aaaagttctt cttcttttct aacgattctc
    41581 ataccttttc caccgcctcc acttgaggct tttatcataa caggatatcc aatttctctt
    41641 gcaacttcta aagcttcttc cttagttttc aaaacagatt ctgaaccagg aacaacaggg
    41701 atattcaatt ccatcatagt ttctcttgct ctagatttat ctcccatcaa aatcatttgt
    41761 tctcttgttg gacctataaa aataatatta ttatcttcac attgctttgc aaattcagga
    41821 ttctctgata aaaatccaaa gcctggatga atagcatcac actttaattt aagagcaaga
    41881 tagattatat tttctatatt attataactc ttacttatat tatttggtcc tatacaaata
    41941 gattcatcag ctatatatct atgaaaacaa tctttatcta tttcagaata gatagcaaca
    42001 gtttttatac ctagttcttt acatgttctg atgattctaa ctgctatatc gcctctattt
    42061 gcaactagta ttttttttat caacttaaat acctcctact acaatggttt tatcttaaat
    42121 aaaggttgat tatattctac tagttcttca ttactaacta atacttcaat tatttcacct
    42181 ttaatttcac ttgttatctc attcataagc ttcattgctt ctaatataca taaagtgtcg
    42241 ccttcttcaa ctacatcgcc aactttaaca aagctatctg catctggact tggagaatca
    42301 tagaatgttc ccatcaaagg agctactact actgatagat tctcattaga tgtgacaggt
    42361 gtatcgttta caactggctt ttctaaagaa agatccacta ctgattcttg ttgtacactt
    42421 aaaacaggtg aacttgtaga ttgagctttt ttagatactt ctaatcttaa atcgctactt
    42481 tcaagtttta catattctaa gttagttgag tctatggcct ttaataattc cttaatttca
    42541 ttgatgttca ttttgttacc cccttgtatt attacctggt gctaatatta tatcacaaaa
    42601 aacaaattta taaaagaaaa agtgctgact agagaatcaa cacatcaata tatcttttaa
    42661 ttttaaatta acaaccagta acttatattt gttttaattt tccattatta atataaatta
    42721 taagtataaa atgaataaaa ttcaatattt tttgcaaaat acaagagaat acaaattaat
    42781 acctcgggaa tttttaagac aaataccaat attatgcaat ttagacttcg ctttctttca
    42841 aattagtatc attttcttta tttttacata ggatgtactt taatttagct atcaaaacat
    42901 tgctatatag gttaaaagtt attagaattg caggaattat aaagtaaact ctagcaccta
    42961 taaaaccaaa aactactgta ataagtatta atcttttatt taaagtaaaa aaaggtatat
    43021 taaaaatact tttgtcggat gtttctggag tataagaata tataactcca aaaatcaaag
    43081 taagcataca aagtggaagt agtgtataac ttgaaattat tcccagaaat cctatacttt
    43141 caaaatattt gctagcacta tttgtataaa caaacatgta tccatttaaa tatgcgcata
    43201 tacatgatat aatgccaaaa gttcccccta aggattgagt gtaccaatta aaaaatttag
    43261 attccatata cctcacctcc taaaactgta tatataatga tatgcattta aatagtaaaa
    43321 tatatcttta tatgtttctg aataaaattt tgttaatttc attaatttat gtttaagaaa
    43381 tttgaagtat agtgtagtat atattaatgt agatgaagtt ttatagtact tatttcatag
    43441 tgcttaatca agttatctta ttatggattc aaaagttgtt tgtagggttt tatattttgt
    43501 tgagctgaaa aatttattat aaatgaaggg atgttttcgc tttggtagat acattagaat
    43561 ttggtcttaa aattttattt tttatattat caataatttg gatgggtaaa ataatgattt
    43621 taagaactga taagcaaata gtaatcaatc ctttgcttat tggtatatct gcagtccttg
    43681 tgatgttgca tacctcacag agtaacattg aattttttgg attagatgtc caatatataa
    43741 gaatagtttt gtatataata tattcactga taattttaat aggaatatgg gctactaaca
    43801 gaagaaatgg aattttttag ataatctatt tctataaaat ttaaaggttg ctagtaacaa
    43861 agcactaata ttagcgttct gttactaaca acctttattt tgattataca cttaaattga
    43921 aaatagaatg attgaataag ttgacagatt attttacatt gacagtaatt agaacttctt
    43981 gagatgtatt taaatcattt ttgtcgctta gtataacttt taccactgct tgacctgttt
    44041 tattaccttt aattatcata tcttcacatg aaagtacact cttatcactt acagatacaa
    44101 taaaatttaa atcttttgga aggttatcag taacttccca gtatttataa taactatcaa
    44161 ttttcttcgt aattattttt ctcaaatcaa tactttcacc ttttgctata tcaacattat
    44221 gatatttaga gtccagttta tactgattat cttttgtatc aataaaattt aaatcgcaat
    44281 ttacatccac accattatga gaaagagaat ttactacatc gtcatcaatc aaataattat
    44341 tggcaagatt tattgaatcc atatctttta gacttaaagc ttccttagga acctctttta
    44401 tattattatt ccaaaaaata aaattgtcta cattttcaag atatgatatt ccttttaaat
    44461 ttgaaatact ctcaccagtt gcataaaatt ctccatctaa agcctttata ttgcttatag
    44521 tcatctcatc tggatttata tatcttttta caactgctct taaatttgca tcaggaaaaa
    44581 tatctttaag ttgattttcg ctcaaaacct tatcatttga atttattgga cttaaagctg
    44641 ctgcagaaat aataaatggt attaaattag ctaaattcat agtaccctcc cacataaatt
    44701 ttttattata ataatttaat ttctatgaga gggttctgtt tccttgttat atatacctac
    44761 tttcgtacac tttattaata taaattaaaa taaatttcta ctattaaact tataaacata
    44821 ttactagtta cgttttttag cttcacatct aaatattcgc ataccttgtg acataaattt
    44881 gtcttcatac tctgttgtaa cattattttc atactcacta tttcctaaat caagagaaat
    44941 attctttaat agccaattat ttgcagcaat ttcatttaaa ctaaactcga ataatttttc
    45001 attatctgtt ttaaagtgaa tttcgccatc atcttccaaa accctattgt acatttctaa
    45061 aaatccagaa tgagtgagtc ttcttttact ccatctattt ttaggccatg ggtcacagaa
    45121 atttatataa attctcgata attctttagc ttcaaagtaa tccaaaatat tgcttacatc
    45181 tccccataaa aatagtatat tattcaaatt agaagcatct gctttttcaa cagcctttaa
    45241 aagaacttct tccttaagtt ccatagcaat ataatttatg tcagggttct gcttagctaa
    45301 agttgttata aacttacctt ttccagtccc aaattcaaca tgtattggat tatcatttct
    45361 aaactttaaa ttccacttgc cttttaattt gtctatatca tctcttaaaa catattttgt
    45421 ataacttaaa agcttttcat ctgcaccttt ttttcgtctt cttctcacaa taattctcct
    45481 tacatataaa aaattagtaa aatacatttt tattatacat tatctcacca aaaaataaaa
    45541 agaactctct taaaatagaa atttatttct ataaagagag ttctaaactt actaaaaact
    45601 taatcttagt ggcaccctga acaaccagag catcctcctc caccttgatc tttcatattt
    45661 tcaggaataa ctctaaatcc aaatcctgta tcttctatta ttatatctcc atactgacta
    45721 tattcatcag agctcattac aaattgtaac tctccaactt cataagttaa gtcatcttct
    45781 tttttctcat ctaaagctaa tccaaaagaa ggacctccac aaccaacacc tgcaaagtat
    45841 actcttatat tattaggttt atcttgattg tcttttaaga tactttttaa agtatcaata
    45901 gctgtttctg gtaaagtaat tttcatcaaa tcattccctt tcaaatattt tattaaaaca
    45961 atatctatta tatacccata caaggtacat aatcaattag tttttgcata ttttactaaa
    46021 acttctacct aatattacct aaggctttaa aatattttat ataatatttt attaccttaa
    46081 ataaataccc tatcataaac ttagtaaaca aataaaatta ttattctaaa aaatataata
    46141 a
//
LOCUS       DAEPXW010000025        45749 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.025, whole genome shotgun sequence.
ACCESSION   DAEPXW010000025 DAEPXW010000000
VERSION     DAEPXW010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45749
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.025"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            96..428
                     /locus_tag="KRM55_001322"
     CDS             96..428
                     /locus_tag="KRM55_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBH1593571.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            590..775
                     /locus_tag="KRM55_001323"
     CDS             590..775
                     /locus_tag="KRM55_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593572.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            802..1887
                     /locus_tag="KRM55_001324"
     CDS             802..1887
                     /locus_tag="KRM55_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH1593573.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            1880..2338
                     /locus_tag="KRM55_001325"
     CDS             1880..2338
                     /locus_tag="KRM55_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593574.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            2373..3464
                     /locus_tag="KRM55_001326"
     CDS             2373..3464
                     /locus_tag="KRM55_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1593575.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            3469..3693
                     /locus_tag="KRM55_001327"
     CDS             3469..3693
                     /locus_tag="KRM55_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593576.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            3703..4266
                     /locus_tag="KRM55_001328"
     CDS             3703..4266
                     /locus_tag="KRM55_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593577.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            4227..4856
                     /locus_tag="KRM55_001329"
     CDS             4227..4856
                     /locus_tag="KRM55_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593578.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            4896..5033
                     /locus_tag="KRM55_001330"
     CDS             4896..5033
                     /locus_tag="KRM55_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1593579.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            5033..5785
                     /locus_tag="KRM55_001331"
     CDS             5033..5785
                     /locus_tag="KRM55_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593580.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            5798..6283
                     /locus_tag="KRM55_001332"
     CDS             5798..6283
                     /locus_tag="KRM55_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593581.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            6290..6439
                     /locus_tag="KRM55_001333"
     CDS             6290..6439
                     /locus_tag="KRM55_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593582.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(6576..7397)
                     /gene="yidA"
                     /locus_tag="KRM55_001334"
     CDS             complement(6576..7397)
                     /gene="yidA"
                     /locus_tag="KRM55_001334"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBH1593583.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            7890..9584
                     /locus_tag="KRM55_001335"
     CDS             7890..9584
                     /locus_tag="KRM55_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBH1593584.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGFCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      9916..10026
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            10130..10501
                     /locus_tag="KRM55_001336"
     CDS             10130..10501
                     /locus_tag="KRM55_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBH1593585.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            10597..11544
                     /gene="trxB"
                     /locus_tag="KRM55_001337"
     CDS             10597..11544
                     /gene="trxB"
                     /locus_tag="KRM55_001337"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH1593586.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            11629..11946
                     /locus_tag="KRM55_001338"
     CDS             11629..11946
                     /locus_tag="KRM55_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBH1593587.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            12215..13501
                     /locus_tag="KRM55_001339"
     CDS             12215..13501
                     /locus_tag="KRM55_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH1593588.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            13613..14086
                     /locus_tag="KRM55_001340"
     CDS             13613..14086
                     /locus_tag="KRM55_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:13745..13747,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBH1593589.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            14118..15428
                     /gene="grdB"
                     /locus_tag="KRM55_001341"
     CDS             14118..15428
                     /gene="grdB"
                     /locus_tag="KRM55_001341"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:15165..15167,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH1593590.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            15684..17216
                     /locus_tag="KRM55_001342"
     CDS             15684..17216
                     /locus_tag="KRM55_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBH1593591.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            17227..18372
                     /locus_tag="KRM55_001343"
     CDS             17227..18372
                     /locus_tag="KRM55_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBH1593592.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            18682..19761
                     /locus_tag="KRM55_001344"
     CDS             18682..19761
                     /locus_tag="KRM55_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1593593.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            19874..20473
                     /locus_tag="KRM55_001345"
     CDS             19874..20473
                     /locus_tag="KRM55_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593594.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(20659..21531)
                     /locus_tag="KRM55_001346"
     CDS             complement(20659..21531)
                     /locus_tag="KRM55_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1593595.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            21948..23351
                     /locus_tag="KRM55_001347"
     CDS             21948..23351
                     /locus_tag="KRM55_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593596.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            23378..24922
                     /locus_tag="KRM55_001348"
     CDS             23378..24922
                     /locus_tag="KRM55_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH1593597.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            24953..26344
                     /locus_tag="KRM55_001349"
     CDS             24953..26344
                     /locus_tag="KRM55_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBH1593598.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            26537..28033
                     /gene="abfD"
                     /locus_tag="KRM55_001350"
     CDS             26537..28033
                     /gene="abfD"
                     /locus_tag="KRM55_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBH1593599.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            28168..28443
                     /locus_tag="KRM55_001351"
     CDS             28168..28443
                     /locus_tag="KRM55_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593600.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            28467..29774
                     /locus_tag="KRM55_001352"
     CDS             28467..29774
                     /locus_tag="KRM55_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH1593601.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVREHLAVEFEKRFKEKY"
     gene            29794..30912
                     /locus_tag="KRM55_001353"
     CDS             29794..30912
                     /locus_tag="KRM55_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH1593602.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVLPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            31199..32119
                     /locus_tag="KRM55_001354"
     CDS             31199..32119
                     /locus_tag="KRM55_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBH1593603.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFIPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGNKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            32234..33391
                     /locus_tag="KRM55_001355"
     CDS             32234..33391
                     /locus_tag="KRM55_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH1593604.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKIGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(33476..34975)
                     /locus_tag="KRM55_001356"
     CDS             complement(33476..34975)
                     /locus_tag="KRM55_001356"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBH1593605.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            35571..36995
                     /locus_tag="KRM55_001357"
     CDS             35571..36995
                     /locus_tag="KRM55_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBH1593606.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPNDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDALFKRLESK"
     gene            37030..39159
                     /locus_tag="KRM55_001358"
     CDS             37030..39159
                     /locus_tag="KRM55_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH1593607.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLIDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPAGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            39189..39611
                     /locus_tag="KRM55_001359"
     CDS             39189..39611
                     /locus_tag="KRM55_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1593608.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            39630..40781
                     /locus_tag="KRM55_001360"
     CDS             39630..40781
                     /locus_tag="KRM55_001360"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1593609.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEDILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      40887..40988
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            41171..41743
                     /locus_tag="KRM55_001361"
     CDS             41171..41743
                     /locus_tag="KRM55_001361"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBH1593610.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            41807..42457
                     /gene="fsa"
                     /locus_tag="KRM55_001362"
     CDS             41807..42457
                     /gene="fsa"
                     /locus_tag="KRM55_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH1593611.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            42609..45533
                     /locus_tag="KRM55_001363"
     CDS             42609..45533
                     /locus_tag="KRM55_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1593612.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        18017 a         5004 c         8487 g        14241 t
ORIGIN      
        1 gttaatatct attttacaga taaataagaa taaacttata atataattgt atctgtaaaa
       61 ttttgtaaaa tataaaaagt atagggggaa taaaaatgaa agtagcttat atttttagta
      121 gtactaatac acataaaatt ctagacaaaa tgataatacc acaacttgaa caaggaactc
      181 atggagtaga cgttctaggg atgtttttct ttatggataa taccttattt ttatctaaag
      241 gtaatcctgt aggcgagaga ctaagtaaat tacatgaaaa aactgatatg ataataatgg
      301 cttgtgacca atgtgctata gaaagaggta tagagaataa tttggttgat ggagctacaa
      361 ttggatgttt cccaaaccta tatgcttgtt taggcagtgc aggtgtggac caagttataa
      421 cgttataaat tagtatagga tacaatccat agaaaaattt attttctgtg gattatttta
      481 agtaaaagat aaattgttta aagtagggga ttaacaaatg tctaaaattt tagttgaatt
      541 tataaacact tgaccatctt gtgatgaaca tggagtgttt ataaaaaaaa tgtcagaaaa
      601 gtatgctgat aaattggaaa taaaattata tcaagcaggg aaagattttt cgtatataaa
      661 aaaatatggg attataacaa aaggaacttt aataataaat cagaaaaaga aatatgatag
      721 attaaataaa gatacaattg aaagggcaat agtagaagct ataaacaata attaaaagtt
      781 taaaaattag gagtatcaaa aatgaatata ttagaaattg ttttaaatgg agttaaagat
      841 actatagtag cttctatagt tacactgaat ggagcatcag gatggcttat gataagtttt
      901 atattggcag gtgtacttca caatgtttta actccaagaa ggtttcaaaa acaacttgga
      961 aataagaaat tttcttcttt aattaaaagt actatctcag gaatgttttt accaatatgt
     1021 agttgtggag taataccact tggaataagt atgtattatt caggagcata tttaggacca
     1081 gtacttgctt ttatgacatc aactccaata ataaatccaa tagctgtagt tctttgtcta
     1141 ggtcttttag gtcctaaagt tacaatcatt tatctaatag ctggtttttt agtaccattt
     1201 ttagtaggat ttttaggaaa ttgttttgga aaagaagaat tatcacttca taatgattca
     1261 gaggaagaag taatagaatt agaagaagaa aaaagaagtt ttatgggaaa tatgattgat
     1321 ggtcttaaat ggtcttttgg tgaattagcc cttactatta gtaaatatgt agtaatgggt
     1381 atggtttttg caggatttat aacaactatt tttccaaata gtataattca aaaatattta
     1441 ggaaatccag gtttgctatc tcttggaagt atagcaatac ttgcatgtgt tatgtatgta
     1501 tgtgctgtag gacatatacc gtttatagca gcccttgttg caagtggagc atctcctggt
     1561 atagcgataa catttctaat agctggagca gctacaaatc taccagaact tataagtatg
     1621 tttaaactta ttggaaaaag aactgttatt atatattctg taactttgac actgtcttca
     1681 ataataattg gatatataac aaatttactt ttagtgaata ataactcagt aaatttagat
     1741 gcaacaaatt cttcaataca gttggcaaat aaactaatgt taaacatacc tgatagtttt
     1801 gagtatgtat gtactatttt aattatttta tttgcattta aatcaataat accaaagatg
     1861 aaagaggtca taggaaatca tgcttaaaaa gatagttata atatcctgta tagtagttgt
     1921 gttaatcatt ttatcaaaaa tagttgatga taacatcaaa gaagatgctt ctattccaaa
     1981 tgtgaataaa gaaacattag aatattttag aaaaaattat aaagaagaca taataacttg
     2041 tgctgaagaa gacttaaata atgatggaaa aaaagattta gtagttatat ataaaaaaag
     2101 caataattca aatgaaatgg tagtcgtagt ttctgataaa aatagccact atataacaaa
     2161 gccaatacca gcacctatag agaatcaaac tataaccttt aaaaatattg atgataaagc
     2221 accaatagaa gtaattgtat cagggtctaa aaatggtaat gtaggatatg ctatttacag
     2281 agtagagggt aaaaaatttg ttgatttatt tggcgaagat atggacaaat gttgctaaaa
     2341 ataaaaataa tacataaagg tgggaaattt atatgaaatt atctaagaag attcaagcat
     2401 taatcttatt tggtgtaatg ggtacatcta tattaacagg atgtagtagt aaaccaaaag
     2461 aaaaagaaga agcaaaaact ggaaaagatg attatacaat aacagtaggt tattataatt
     2521 gtgaccatat gactgcggga ccagtagcag aatcggcagg aatatataaa gatttaggtc
     2581 ttaatgtaaa aactgttgga aatggtaaag ttcctgaagc tatggcagca ggaaaaatgg
     2641 atgcaggtta cataggaact aaggggttag ttggagcaat acctaagggt tcaccaataa
     2701 caatagcagc taacaaccat actggtggtt ctgaatattt aatagtttca aaagatataa
     2761 aagaacctaa agatttaata ggtaaaaaaa ttgcaacaga tatgagtgat ttcttatgga
     2821 caagtgatta tggtccagaa acaggtctac caactgaccc atcaaaatat gaagttgtaa
     2881 atatggattc agacaaagat aaatatttag ctcttaaaac tgggaaaatt caagctttta
     2941 catcttgtga cccttggggt tctgtagctg aaaatgacgg tgcaggaaaa ataatagcat
     3001 ctactcaata taaagaaaaa gctaatggca aagaatataa ctgttgttca ttctcattaa
     3061 acaaaaactt tataaaagaa catccagatt tagcaaaaaa attggttcta gcacatacaa
     3121 aagcaataga atatatatat acaaatccag ctgaagcagc taaaatattt gcaaaatatt
     3181 ataatgtaga agaagaagtt gcacttagaa ctatctataa gaagactgtt ggagaaggta
     3241 gaactcttac ttggaaagtt acaggtgaag aatataaaaa taatttacaa atgtataaag
     3301 atttaaaggc tttagatgat atacctaaat atgaagatac gattgataca agcttattgg
     3361 actcttgtgg agctgatgat tttgacaaat ttataaaaga aaaagttaac ccagagtttc
     3421 ctgaaggtat gagttatgaa gactggaaag caaaggtatt ataaataaat ggagaatatg
     3481 aaaaatataa taatactttt tatcattatt ttgggaagta tatttataat attttttaat
     3541 tttgaagata aagaagaaat aaaaggaaaa ttaagaatag gggtatctga tgatacctct
     3601 ggttttgtaa taaattatat ggtaaataga gactactttg aaaatataaa agtaagtgat
     3661 ataatggata tttttacaat taatgattgc tgagcaagta caatgcagtg ggctctgagt
     3721 tcagaggaaa tagatatagc aatcatatgt aaagatgctg caaaacaata tgtaaatgta
     3781 aatagtggat ttgaaattgt tggtactgta gttcaaaatt ctgatatatt tctattaagt
     3841 gataataatc ctgaaaagat aggagtcatt caaaatagag attaccagtc agaattggtt
     3901 aaaaaatact acaagaatgt ggaagtagct cccttattag ggactgcact agcatatgga
     3961 ttagaaagta atttagtaga tggtgttgta atagattgca taaagtcaat tgggttagag
     4021 ggcaaaagaa aatctacaac taaattagga gattatgata cctatgtatt agttgtaagt
     4081 aaagagttta aaaaaagtaa agcatatagt gattttataa cactttacaa taaaagtgtt
     4141 gatgctttaa agaataaagc tacatttaag aaagcattaa aagagtacag gaatataaga
     4201 aatatagata tggaggaaat aagcaattgg aaattaaaat ttctaaagat aaaagcgata
     4261 gattaactaa gaaaaaaact gatggtagta tggatatttt atataaaata atactattag
     4321 ttattatatt tttagtctgg cattttgcag caaaagatat agggagttct ttgttacttc
     4381 caatgccagt agatgtaata aaaggtttct ttttctgtgt gacagatgca gagacagtca
     4441 ctaatctttt tataacattg cagagagtac ttaaaggttt tatgtatgca ttattgtttg
     4501 ggcttccaat aggatttatt atgggatttt ctaaaacttt tgaaagggtt ttatctccag
     4561 tagtagattc tgtaaggcaa gttccaataa tggcatgggt tcctcttact atagtatggt
     4621 ttggtatagg agatggtcca acaatatttt taatagcttt ttcaggggtt ttccctataa
     4681 ttttaaatac tattcaagga gtaagagcaa tatcaaagga ttattataat gcagctagaa
     4741 gtatgggagc atcgccaatt gtgatattta caaatgtaat tgttcccgca tctcttccag
     4801 atatactaac tggttcaagg attgctataa gtacaggatg gatgtctgtt atctgagccg
     4861 agtttatagc tacgagtgcc ggtctcggtt actcaatggt acaagctcaa acattaatgc
     4921 atacagatgt attaattggg cttatgatat ttgcagcttt aataggattt ataatagata
     4981 gggtattaaa gtttataaat aaaatccttt gtagatggag gtttgcagat taatgaagtt
     5041 aagtgtaaga gatataaata agacatttgt aaataataga gtacatacaa aggttttaga
     5101 agatataagt atggatatag atgatggaca atttgtctgt cttttaggac catcaggttg
     5161 tggaaaaaca actttactta ctataatagg tgggtttcaa aaatcagaac gtggagatgt
     5221 ttttataaat gataaaagag ttaaaaaacc gggcatagat agagctttta tatttcaaaa
     5281 ttatgcttta tttccttgga aaactataag aggtaatgtt ctatttccta tgaaacagca
     5341 gaaaatacca aaagaaaaaa gagaagaaat gctagaagaa cttttggtta tgtcagactt
     5401 gaaaggaaaa gaaaaactgt ttccgcatca attatctgga ggaatgaaac aaagagtggc
     5461 catgataaga gctttagcat gtaatccaga ggtattacta atggatgaac cattaggagc
     5521 tgtagatttt caaatgagac aaaatttaca ggaagagcta gaacgaatat ggataaagaa
     5581 gaaaataact gcattaatgg taactcatga tgttgatgaa gctgtatata tgagtgatag
     5641 agttatagta atgtcgagag ataaaggaag aattattgat gatataaata tagatattcc
     5701 aagacctaga attagaggaa gccaaaaata tgaagagtac aaaaacaaat taactgatac
     5761 tttatcaaag tgttatgaag tttaaagagg agtagacatg agtcaaatag aaaaatacaa
     5821 tagtttggat aatacacaac agaaaataag aatctctatt atggatatga taatagataa
     5881 aggttctagt gttacacttc aagaagtgac tgaatatgta agtaaaaagt tgaatataga
     5941 aaaagaatat atagaaagga cactacaata ttttatttat aaaaatataa tggttgttga
     6001 tgggaatagt ataaatttta tatatcctgt atcagcattg ccaacaaatc ataaagtaac
     6061 tttgagagat aatagaagtt tcagtgcaat gtgtgctata gatgctatag gaacctcttg
     6121 cacattcaac caagatataa aaataaactc tatttgtagt gctacaggta aggaaataga
     6181 agtaattata aaaaatgaaa agattgagta tgtgaataat ccaaacttaa gagtgcttca
     6241 tataaatctt gataagcatc taaattgggc tgctagttgc tgaaatataa tgaatttctt
     6301 ctggacgaag agtgattttg atgcttggac aaacgaagca ggattatctg atgatgaaga
     6361 tatatattgt ttagatatta atgaggcaat agtagaatca tataaaatat ttaaactcaa
     6421 acaaaaggta ctatcataga tatacatata tgaaaaacta aaaatgacct ttagataaaa
     6481 atgataggta atatccatac tatataaatt agtatagagt agggatgtga aaagtattta
     6541 aatctaaagg tatattttta gtttttttta gatgattaga tagccttatt aagtatatat
     6601 ttatttataa cctttgcaac tccattttca ttattagtat cagtaacata atctgcaatt
     6661 tcctttatac tattacgtgc attccccata gccacaccaa gacctgcata ctttatcata
     6721 tgttggtcat tttcttcatc gccaacagca atagcatttt ctataggtat atttagattc
     6781 gtacataatg ttttaagagc agttccttta ttagtagttt tacctaaaaa ttctagataa
     6841 aaaggagcag accttactat agtatattta ttgaataaat ttttaggtag ttgctgtatg
     6901 atttcttcca atctttctgg ttcatcaact atcataattt tacagatttt aatagattca
     6961 tcaattttat ctttttgtat atatttgact tctatattat ttaatttcgc ttcatgaagt
     7021 gtatatttgc caggcgtttc atttggtgta attaaatttg tcattgtatt tatgtgtatt
     7081 ttagtcttat attttttaca aacgttatta tatataaaat caaaatcatc taaactcatt
     7141 tctacatcat gtatgatttt ctcactttta acttcttgaa taattgctcc attaaagcat
     7201 ataacataat caccttcatc tgttaaattt agttgattta gaagttcttt tacaccagga
     7261 agaggtctgc ctgttgttat aactactttt gccccagccc tttttgcctc ctgaatggac
     7321 tcaaagactt caggagtaat ccttttttgt gtatttaata ttgttccatc aatgtctagt
     7381 gcgattaatt tgtacatatc aacctccaat aaattatata ctcaaatttc ctgtgaaaac
     7441 gttgacacag ctagtgttga acaaagtttc agtgggaaat atggtttgtt ttgtatacta
     7501 ttatatcaag agataagtaa tttagaaagt ttaataatat taattttttg ataaaaatat
     7561 tacttatgtg agatgagaat gtaaaaactt tgtaatcaat aattccaaaa ttcttaatta
     7621 caaataatgg tatcgtttgc attgttaata taaataaatg tatattatat agttagaagt
     7681 ttgaataaat agactgatgg taatttgtta tattagttag ttttgtgtta taaaatattg
     7741 taattccatt aatcatatgt tattattcaa catgattata atataaagaa tatttgatat
     7801 atataataat ttataaaaga gtattacata gtacatgtaa atctatattt ataaatacaa
     7861 taaagtaagg ttgtaaagga gtgctttaaa tgaagttttc agagtttaag tatgaaagac
     7921 ccaattataa tagtatgaaa aaagagtttt tgagttgtgt agaagatata aataattctc
     7981 gtaattataa agagcaacaa aaaaatatac ataagattaa tttattaaga aataaaatag
     8041 aaacgttgtc aaatatagct tcgataagat atagtacaga cacatttaat aaattctaca
     8101 aagaagaaaa aaattattgg gatgaatata tgcctttgta tgaagaatta aattcatatt
     8161 tttataatgc cattgtaaat tcaaaattta aatatgattt gataaaagag tttggagagc
     8221 aatttttcac aatagtagag tattctttaa aaagtttttc caaagaaata ataagtgaat
     8281 tgcaggaaga aaataaattg tgttcagagt atactagact tttagcttca gctgagataa
     8341 tgtttgatgg gaaaataaga aatttatctg gtatggggaa attcatgtat tctaagaata
     8401 gaaaaacaag agaattagca aacaaagcat attataattt ctttgaagaa aatgaaacta
     8461 aatttgatga tatatttgat aaattggtta aacttagaga taagatgtct aaaaaattag
     8521 gttttgaaga ttttgtagag cttgggtatg ttagaatgat gagaagtgac tacagagaat
     8581 atatgataaa aaatgttaga aaacaagtac taaaatatgt tgttccaatg gcaaatgagc
     8641 tttatgaaaa acaagctaaa agaattggtc tagaatattt aagttacata gatgaaggcg
     8701 tggaattttt aacaggaaat gcaagtttaa agggagattc aagatacata attcaaaatg
     8761 gtaaaaggat gtattctgaa ctgtcaaaag aaacaaatga attttttgat tttatgttag
     8821 aaaatgaact tatggattta gaaacgaaga aaggaaaagg agctggaggg ttttgtactt
     8881 atataccaga ttataagtca ccattcattt tttctaattt taatcaaact gctgatgata
     8941 tagatgtatt aacacatgag gcaggacatg catttcagtt gtatatgtct agatggattg
     9001 atatgccaga aattaatttt ccaacgcttg atagttgtga aatccattca atgagtatgg
     9061 aatttataac atggccgtgg atggatttat tttttaaaga agatacagat aagtacaaat
     9121 tcactcactt atcatcttca attaaattta taccttatgg agtaattgtt gatgaatttc
     9181 aacactatat ttacaaaaat cctaatgtag ataagtcaaa acgaaaagaa atctggagat
     9241 ttttagagaa aaaatactta cctcatagaa aatatggtga taattctttt ttagagagag
     9301 gttgttggtg gtttaaacaa ggacatatat ttaaaaatcc gttttattat atagattatg
     9361 tattagctca aatttgtgcg ttacaatttt ggaaaaaaat gattcaagat agagatgcag
     9421 gatggaaaga ttatataaat atctgtaaag ttggaggaac aaaatcattt ttagatattg
     9481 tgagtatggg aaatttgtat tctccatttg atgatggctg tattgagtct attataggtg
     9541 atgttaaatc ttggtttgat gaaataaatg acagcaaatt ataaaaaatt atgagaattt
     9601 tattgtataa aagtgaaaaa ttaaaaaata tataaaaagt gattatttgt tgtgaaaata
     9661 gtcttgtttt taactaaatt gataaaataa actaaaaaag atttgtactt aaaaaaaaaa
     9721 gaaaatacaa gaaatatgca atatcaacat ttggaaaaaa aagtaaaaat gtatacaaaa
     9781 tacatataaa aaaactattg caaattttat agaatgttta tatacttaag tcaacagaga
     9841 tagaaaaaag ctatttatag aaaacaaagg ataaattgct taattttaaa ttttctgaaa
     9901 aaaataataa tccggatgaa gagtatggga gactgcttta taaaaagcga ccgaagggac
     9961 aagtttaatc ttacttaccc aaaagattag atgaaattct caggtaaagg tgactgtact
    10021 tggacggggc tctgaaaatg attttaacag ggaagacaaa ttgggagatt tgtttttcct
    10081 gttttttatt tatcaagtaa taaataaaag tttgaaagag agtaaaaaaa tgataataat
    10141 tacgaataat ccaaaagtaa aagaagaagt tcaaggcaga gaagttttgt ttaaagacac
    10201 aacttatatt ggaatcttag aagcaagtag agatttgata catgaaggtt atgaactttt
    10261 atctcatcca ctctatggga gtgtaaagcc aaatgaaaca ccttacagga ctgttatact
    10321 aaagaaagga aatcgtttgg atataaactc tttaacctta attgaagaag caatcatcac
    10381 tgcaagtaaa tttcagaata ataaaaagac tccaaaatgg acagaaagtg ttcaagatga
    10441 ttttagagta attgattatg atatatttta taatacaata caaagaatgc agtatgaata
    10501 aaaaaaattg ttaaaaagtt attaaaacag cctaaatatt aaatctaatt taatattaaa
    10561 taaaatgaga aatttaattg gggaggataa gtcaaaatgg aaaatgtgta tgacttagta
    10621 ataattggtt caggaccagc agggcttgca gcaggtcttt atggagcaag agcaaagtta
    10681 aaaactctaa tcctagaaaa agacaagact ggtggacaaa ttgtaataac acatgaaatt
    10741 gcaaattatc cagggtcagt tccaaatgca acaggaccaa gtttaatagc tagaatggtt
    10801 gaacagtgta aagagtttgg agcagaaatg ctaagagaca acattgttga tactgagcta
    10861 gatggagata taaaagtttt aaaaggggaa aaggcagaat atagagcaaa agcagtaata
    10921 ataggaacag gagcaacacc aagaaagatt ggttgtcctg gagaaaaaga acttactggt
    10981 aaaggggttt catattgtgc aacttgtgat gcagatttct ttgaagattt tgaagtattt
    11041 gttgtaggtg gaggagacag tgcattagaa gaagcaatgt atttaactaa atttgctaga
    11101 aaagtaacaa ttgtacatag aagacaagga tttagatgtg ctaagagtgt tgaagaaaaa
    11161 gcaaaagcta atccaaagat agagttttta ttagatacag taattgaaga aatcaaaggt
    11221 gatggaatat tagaatcagt tgtatttaaa aataaagtta ctggagaaac tcatgaatac
    11281 tttgcagatg aagaagatgg aacaatggga gtatttgtgt tcgttggatt agatgctcaa
    11341 actgatttat tcaaaggtaa agttgatatg gatgaaaaag gttacataat aactgatgaa
    11401 gatatgagaa ctaacatacc aggcgtattt gcagcaggag attgtagatc taagactcta
    11461 agacaggttg taactgcaac taatgatgga gcaattgcat ctatagtagc tgagaaatac
    11521 attgatgaaa aatttgggaa ctagaatctg taaattaaga aatagtgtct gtaaatttaa
    11581 tgaataatat ttaaaattaa aataaaaatt tcaaggggga ataagaaaat gttagattta
    11641 gataaggcta catttgaaga agaagtttta aatgcagaag gttttgtatt tgttgatttt
    11701 tggagtgaag gttgtgagcc ttgtaaagct ttaatgccag atgttcataa attagctgag
    11761 acttatgggg ataaaataaa attctgtaag atggatacaa caaaagctag aagattagct
    11821 ataaaacaaa aagtattagg tcttccaact atggctatat acaaagatgg agaaaaagta
    11881 gacgaagtta ctaaggatga tgctacagtt cctaatatag aaaacatgat taaaaaatat
    11941 ctttaatatg ttgataaatt attaacatta aaagaaaaaa tctattttta tctgaagata
    12001 agaagaaaaa ggtttttatg tccaactttg ttaaaaaaat aattttaaat aaaataattt
    12061 ttttacaata aatatttttt agtaataaaa taaagattta aggcataaaa acacaataat
    12121 atatctttaa aaaaataaga taaattgtaa aatgatataa ttttgagaaa aactcaaatg
    12181 catatacaca aattaaataa caggaggtgc aagtatgcgt cttgaattag ggaaaatctt
    12241 tataaaagat attcaatttg gtgatgtaac agaagtaaaa gatggagtat tattcatcaa
    12301 taagcaagag atgctacaag aaattggtgg agatgagcat attaaatcta tagatataga
    12361 attagctcgt ccaggtgaaa gcgtaagaat aacacctgta aaagatgtta ttgagccaag
    12421 agtaaaagtt gaaggtaatg ggggaatctt ccctggtatc atgtctaaag ttgacactgt
    12481 aggagaagga aaaactcatg ctttaaaagg tgtagctgtt gtaactactg gaaaaatagt
    12541 aggtttccaa gaaggtataa tagacatgac tggagaagga gctaagtaca ctccattttc
    12601 taaattaaat aatgtagtag taatagctga acctattgat ggtttaaaac aatacgctca
    12661 tgaaaaagct gttagaatga taggattcaa agcagcaatg tacttaggag aagtagcaag
    12721 aaatcttact ccagatgaag tttcagtata tgaaactaaa cctcttcttg aatcaataaa
    12781 agaatatcca gagcttccaa aagtaggata tgtttacatg cttcagactc aaggtttatt
    12841 acatgatact tatgtatatg gagtagatgc aaaacaaata gtaccaactt tattatatcc
    12901 aacagaatta atggacggag caattgtaag tggtaactgt gtttctgcat gtgacaaaaa
    12961 cccaagttat gttcatataa acaatggggt tgttgaagac ttatatgcaa gacatggtaa
    13021 agatataaac tttgtaggtg taattataac taatgaaaat gtttatctag cagataaaga
    13081 aagatcttca aactggactt ctaaattatg taaatattta ggattagatg cagttatagt
    13141 ttcacaagaa ggttttggaa atcctgatac tgaccttata atgaactgta agaagataga
    13201 aatgcaaggt gttaaaacag ttatagttac agatgaatat gctggacgtg atggaggttc
    13261 tcaatcactt gcagatgcag atgtaagagc tgatgctgtt gtaacaggtg gaaatgccaa
    13321 ccaagttgta gttcttccta agttagataa agttattgga catttagaag tagtagatgt
    13381 aatagctggt ggttctgatg gaagtttaag agctgatgga actattgaag ttgaaatcca
    13441 agctataaca ggtgcaacta atgaaacagg atttggtcat ttaactgcta aaggatatta
    13501 agaagtattt tattaaacga ttgagtaatg ttaataaaac atattataga taattataat
    13561 aagtgttata gatatataaa aatatattag aaatataata aggaggatta ttatgagttt
    13621 acttagtaat aaaaaggttc ttataatagg tgaccgtgat ggtataccag gacctgcgat
    13681 agaagaatgt gtaaaaacag tagaaggagc agaggttgtt ttctcatcta cagaatgctt
    13741 tgtctgaaca gctgctgggg ctatggactt agaaaatcaa aacagagtta aagatgctgc
    13801 tgataaattc ggagctgaaa atgttgtgat tttactaggt gctgctgaag ccgaagctgc
    13861 aggtcttgca gccgaaacag taactgctgg agatccaact ttcgctggac cacttgctgg
    13921 agttgcctta ggattaagtg tttaccacgt tgttgaggaa ccaataaaat cattatttga
    13981 tgaaagtgta tatgaagacc aaataagtat gatggaaatg gttttagaag ttgaagaaat
    14041 agaagaagaa atgtctggta taagagaaga attttgtaaa ttttaatgcc taaaagcaaa
    14101 aggggtgaaa ctaagagatg ggaaaactaa aagcagtaca ttatattaat cagttctttg
    14161 ctggtatagg tggagaagaa aaagctgata ctaagccaca tgtggcagaa actttacctc
    14221 caataagttt acaacttgat aaattattag gtgaagatat tgaaatagtt ggaacagtag
    14281 tttgtggaga tagctatttc aatgagaata tagatagtgc aagtgaagaa gttttatcaa
    14341 tggtaaaagg ttttgaacca caacttttca tagctggtcc tgcatttaat gctggtagat
    14401 atggggttgc tgctggaaca ataactaaag ttgtaaaaga tgctttgaat ataccagctt
    14461 taacaggtat gtatgttgaa aatccaggag cagatatgtt caaaaaggat gtttatgtag
    14521 tagaaacttc tgattctgca gcaggtatga gaaaggcact tcctaagata gctaaacttg
    14581 cagtaaaact tgctaatgga gaagaaattg gaactcctaa agatgaagga tacatagcta
    14641 gaggaataag agttaactac ttccatgaag acagaggttc taagagagct gttgacatgt
    14701 tagttaagaa aataaaaggt gaaccatttg aaactgaata cccaatgcca aactttgata
    14761 gagttgaccc aagtaaagct gtaaaagatt tatcaaaatg taaaatagct ttagttactt
    14821 ctggtggtat agttccaaaa ggaaatccag atagaataga gtcttcttca gcttctaaat
    14881 atggaactta ttctatagca ggagttatgg atttaacaga agagacttat gaaactgcac
    14941 atggtggata tgacccagtg tatgcaaatt tagatgcaga tagagtatta cctgttgatg
    15001 ttcttagaga tttagaaaaa gaaggtgtaa ttggaaaatt acatgagact ttctatacaa
    15061 ctgtaggtaa tggtacatct gttgcaaact ctaaaaaata tgcttctgaa attggagcag
    15121 cattagtggc tgatggtgta gatgcagtaa tattaacttc tacatgaggt acttgtactc
    15181 gttgcggtgc aacgatggta aaagaaatag aaaaaactgg acttccagta gttcatatgt
    15241 gtacagtagt acctatttca ttaacagtag gggctaatag aatagttcca actatagcaa
    15301 tacctcatcc acttggaaat ccagcgcttg accctacaga agaaaaagcc ctaagaagag
    15361 gccttgtaga aaaagcatta aatgctttaa ctacagaagt agatggtcaa acagtatttg
    15421 aaaaataaaa ataacacaca catatattat atagataaaa atataaacac acactaaaaa
    15481 taaaaaataa ctatacacaa aaaaataata tagatttcat gaatggataa attggagtta
    15541 ttcattcatg aaatcttaaa aaatgccaaa atacataaac aataatagaa tcaaatatac
    15601 aataaaatac aatgattaga gcttttaata agtttaataa gattaaaaaa taagtgttca
    15661 taaaatttat ggaggtgcac aaaatgactt atccagtttt aaaaggggca ggctatgtac
    15721 ttattcatac tccagatatg atagtgcaaa atggaagtac ttgtacagtt gaaagagcaa
    15781 caaatccaga ttcagaattt ttaaaagaag taagtaatca tataagaagt tatgaagatg
    15841 tagttaacta catgccaaat caagtttata taggaaatag aagaccagaa gaattaagag
    15901 atttaccaat gccatggtgt gaacaaaaga ttgagggaac tagaaatggt aagtttggag
    15961 aaataatgcc tcaagatgag ttcatagctt taatgcaaat aagtgatgca tttgatttag
    16021 taaaattatc acaagaattt attgatgaag taaagccaaa aatcgaaaat aactaccctg
    16081 aaattgcacc atttgtaggt aaattaaagg gtgatgatat agaagaaggt aaagaattag
    16141 tagcaacaca catagctgaa ggattatacc atgatggaaa atttgttggt tatgtaaaaa
    16201 gagcacatga tgtagatgtt aacttaaatg cccatacaat gtttgaaaat ctagtagtaa
    16261 aagcatctgg agttttatct gctattcaaa tgctaagaca tagcaaaata gaccctgctg
    16321 aaatagatta tgttattgag tgttcagaag aagcttgtgg agatataaac caaagaggtg
    16381 gaggaaactt tgctaaatca atagctgaga tagcaggact tcaaaatgca actggttctg
    16441 acacaagagg attttgtgca gcaccaactc atgcattaat tcaagcagca gctttagtaa
    16501 aagctggtat acataaaaat gtaatggtag tagcaggtgg agcaagtgct aaacttggaa
    16561 tgaatgctaa agaccatgtt aaaaaaggtc ttcctgtact tgaagatgtt gttggaggat
    16621 ttgcagtact tgtatctgaa aatgatggtg taaatccagt tataagaact gatttaacag
    16681 gtaagcatac tgttggaact ggttcttcac cacaagcagt tatgacagca cttataactt
    16741 caggtcttga tagagctaat ttaaaaataa cagatgttga tgtgtattca gttgaaatgc
    16801 aaaacccaga tataactaag ccagcaggag caggagatgt tccagaagca aactacaaaa
    16861 tgataggggc acttgctgtt aaacgtggag acttagaaaa gaaagaattg aaagattttg
    16921 tttctaacaa aggattacca ggatgggcac caactcaagg acatatacca tcaggagctc
    16981 cttatatagg atttttaata gatgatttaa ctacaggaaa tagaaataga gctatgatag
    17041 ttggaaaagg tagtttattc ttaggaagaa tgactaactt atttgatgga gtatctttta
    17101 tagctgaaag aaatacaggt gttactgaag agacttcagg aatatctaag gatgaaatta
    17161 agaagataat agctgaatct atgaaaaaac tagcattaga tatgttagaa gaataggggt
    17221 gaggatatgt caaaaaaagt aatcgcagat gtattcttag aagtagctaa tgcaatagaa
    17281 agcggcgaat ttggcaaaaa agtaaaaatt ggtgttacta cacttggaag tgaacatggt
    17341 gtagaaaaca tggttaatgg tgcacaatta gcaaaatcta atttatttga tattgtgctt
    17401 attggaccaa aagtggaaac tgaccttgaa gtagttgaag ttaatgatga aaaagaaatg
    17461 catgcaaaaa tggaagaatt attagattca ggatatattg atgcttgtgt tactatgcat
    17521 tataattttc caataggtgt atctacagta ggtagagtaa taactccagc aaaaggaaaa
    17581 gaaatgatac ttgcaacaac aacaggaaca agtgctacta atagaataga ggcaatggta
    17641 agaaatgcca tttatggtat tgctacagct aaatcaatgg gtaacaaatg cccaaaagtt
    17701 ggaatactta atgttgatgg agcaagacaa gttgagaagt gcttaaaaga attaaaagat
    17761 aatggatatg acatggagtt tgcggattca attagagcag atggtggatg tgtaatgaga
    17821 ggtaatgatt tacttgtagg tgcacctgat gttatggtta ctgatacatt atctggaaat
    17881 atatttatga aagtattttc ttcatatact acaggtggag attatgaagc tcaaggcttt
    17941 ggatacggac ctggagttgg agaggactat gatagaaagg tacttatagt atcaagagca
    18001 tcaggttctc cggtagtagc aaatgcttta aaatacgctt atgatgttgt aaagggagat
    18061 ataagtaatg ttgcaagaaa tgaatttgca aaggttaaaa aagcaaaatt tgatgacatt
    18121 atatcctctc ttactaaaaa agaagttaaa gctgaaaaag tagaagttaa aatgccagat
    18181 aaagaaattg ttactcgtca aatagctggt gttgatataa tggatttaga agatgcagta
    18241 tctgagttat ggaaaaacgg aatctatgct gaaagtggta tgggttgtac aggtccaata
    18301 gttttagtaa atgaagctaa aggagactta gcagttgaaa ctttagttaa agctggatat
    18361 actgcaaaat aagtacattt tttatatgta aataagaaca tatagttata attttattga
    18421 ttataattat atgttctttt tattttatat cttgtcaata tttatatatt aacacaatcc
    18481 atttatttga ttctctagct aatttattat atttattcag ttaaaattaa gctttctaac
    18541 taaataaaaa ctaatgaagt attaaaatga aattgataaa atatgaaaaa attttaggaa
    18601 taaagtatct gttagataaa aataagatta attagtgata taatataatt aagataaaat
    18661 ttattatttg gaggcaaaat catgagcaga gtaaaaaatg tagtagaatt gttggaaact
    18721 aaaggtgttg atgcactata tctaacaaag aaaactaatg taaactatat aagtggtttt
    18781 cctgatgaag aagcatatgc agtgatttgc aaagatggaa actttttagt tactgatagt
    18841 agatatatgg agcttgcaga aaaggtttgc aaagattttg aaattataaa ttggcataat
    18901 tttgatagaa gtgtggcaaa ggcagttaaa agtgtatgtg ataaagtggg tataaagaaa
    18961 cttgggtttg aaagaactaa tatagtgttt gataaatatg aagaacttaa aaatctgatt
    19021 gagaaggata atggagaatt aatacctaca gaaaatattg tagagacttt gagatatgta
    19081 aaagacaaag atgaaatcaa aaatacaaga aaagcttgtg aaatagcgga taaggcatta
    19141 gaagaattga ttccacatat aaaagctgga gttagcgaaa ttgaactggc tacaaagtta
    19201 gagtacttta tgaaaatgaa cggagcacaa aatatagggt ttgaaactat actgatatca
    19261 ggagcaaaga cttcattgct tcatggtaag cctagtgata agattataga aaaaggtgat
    19321 tttgtactta tagactatgg cgctatgtat aatggctata tatctgatac aactagaact
    19381 tttatagttg gaggagcttc tgaaaagcaa ttagaaatat ataatttagt taaggaagct
    19441 caaaatgtag gggttgagaa catgaaagct ggtgtacatg cgacaattcc agatgctgag
    19501 ataagaaaag ttgtcaaaaa atatgaagac tattactatc aaggtatagg acatggagtc
    19561 ggtagagatg ttcatgaaga acctttcatt ggtaattatg gtgataaaat catagaagag
    19621 ggatgtataa taacaatgga accaggtatt tatttccctg gatggggtgg agttagaata
    19681 gaagatactg ttttgattac taaaaatggt ccagaaagac ttactaaatt ccctaaagat
    19741 ttgatgattt tagacaaata atttaattta tatatatttt tttacataaa atataacata
    19801 atctcactat taagctctat ttacatatta tagtaaagag ggcttaattt tattgtgaga
    19861 ggtgatagta tatatgtata aaaaacataa atttataaaa aatataaaaa aagcctggta
    19921 taaaatcaaa ttaattgata gatgccttat aattgtaatg gcaatattaa tgtttcaatc
    19981 tatatataat ttatttgtta atgaagtaaa ttcacaagat actacaacta ttgatgtagt
    20041 agtaagaacc acttcagcag ctatatttgg gtatttttta agtgctaatt ttataaagag
    20101 acctttaagg aagtatacaa atactgatgt atcttcaaat ctttttatag ataataattt
    20161 atccccaaaa ggtcaagagt ctaatcaaaa taatataatg aatgtcaaaa ataccattgg
    20221 atttacttca gaagctgata attatgaaaa gaaaatacct attaataata atgaaggttt
    20281 tgaagaagga gaaactagtg aattgcaaat tattatagct actgtaattt gtatagtagc
    20341 attaacagta ctttttgttg taagaaattt tacaactaca acatcagctt ctttaggtac
    20401 tatttcacag atgagagatt ttgtctcagg atgcgtgggt tttttgctag gttgtccaag
    20461 taaacctgat taaaaaagta ttatcaataa aaggtatttt aaaaagtatc agtataataa
    20521 tatttagatt taaatgtata caattataat tctaaacatt ctatattgta tttttatact
    20581 gatactctaa actatactat ttattaaaat attttaacat tgtatttaaa caaaatatta
    20641 tatctgtata atataaattt agtttatatg aatagatgcc atatactcaa taaaaagttt
    20701 catactatga gatatgtatt gatttcttct ccaaagaacc ccaatattcg cagtaattgc
    20761 acgttctaat ggtattgaac agagattttc tgtattttga aatatttctt tatacaatat
    20821 tgttgaagcc aagtcatttt ctagtaaata acgtatggta gaaagttgat ttgagtgtaa
    20881 aattatattt ggcttagctt tttcaagtct ttttgtaata atcttatagt gataagaacc
    20941 ttcagataag attacaaaag gtacattttt taacatataa ttcgatataa tgggatgttt
    21001 tgccaattca tttttgggat ttgtaactaa gtataattct gttttataga ttgtctttga
    21061 atctatatca tcataaatat cactgtcaat tataccaata caaaaatcaa gtgtagattc
    21121 ttcaatcatt ttagctccaa caaatgttgg aacttcaaaa attttaagct ctatatctgg
    21181 ataaattaca ttaaatctag gaagtatttt tgaaagcaaa aacgtaccta aaactgtagg
    21241 aatacctatt ttgagagaag cttttctctt ttttcctaaa tcaagtgcgt cacattgaaa
    21301 atcctcaaat tgttttataa aatgttttga cttgtctaaa aaaatttttc cttcaggcgt
    21361 taactctatt ttattaccta ttctgtaaaa aagttcaaag ccaagttctt tttctaattc
    21421 tttaattgct aatgttatgg atggttgaga aatatgaata ctttccgcag ccttagtcat
    21481 gtttttatat ttacagacag tttgaaaata gtataaatag tttatattca tttggtatta
    21541 gttcctttca tttacatatt agtgacaagt atataattaa caatagcata agttttgtat
    21601 attgttgtaa aaaaatagaa tagttttaaa ctatcatagc ataagttttt gatattttca
    21661 atctattaag aatagtgcta ttattaaatt aacaaaagag aatagctggt atggtttaga
    21721 gtaaatcaat ctatattaca gttatatcaa cgaatatcaa aaaattatct attagaaaat
    21781 aaaaattatt tttacaatta aattgttaat taaatcataa agaaaaaagt gatattaaca
    21841 agataaaatt tttttaatca gaaatgttaa tttaataaca aaatagagta ttggggagaa
    21901 aggagaaata tattttttaa taatatttgt taatttaata acgaaaaatg aaagggagtg
    21961 atttagtgaa gtttgaattg atggattttt taatgaatcc ttttgtcctt atgtttgctg
    22021 cagtaattac aggaatttta tttggaaaaa ttaaatttgg gaagtttaat tttggggtat
    22081 caggagcatt atttacagga ttatttattg gatggcttgc atatagcttg gggaatctaa
    22141 taatagcaaa aggggaaaca gcagcaggat ataaggcagc aactgtaatg atgggtaatg
    22201 gaattatttc ttctgacttc tttgatttct ttttaataat atttgttgca gcagttggtc
    22261 tattggcagc aaaagatatg aaagctgtat taaagaagta tggagcaaga tttgtaattt
    22321 taggagttct tataactttt ataggtggct ctatgactta tgcaatgact ttactatcaa
    22381 gtgataaagg aagtagtgct tatgaagttt ctggcgttta cacaggagca ttaacaagtt
    22441 cgcctggatt agctgctgct ttagaaacag ctggtaaaca tgcagaagat gtatcaaaag
    22501 aatttgaaaa agcttcaata aaagataaaa aagaaatttt aaaagtagtc gacccagaag
    22561 gcaaattgga tgtgaataca actacatcac tgactcaaga gcaaatagat aagtatattg
    22621 catatgctga agctggtgtt ggtataggtc atgcagtcgc atatcctttt ggagttttaa
    22681 tagtaatctt aggtgtaaat ttccttccaa aattatttag gatggaccta aaagaagaaa
    22741 gaagaaaata tgagaaggaa atgaaggaag caagagatag tgtttctggt aaaacgatac
    22801 cagaagttcc atttaatata ataacatttt tcttgacatg tttagctgga tacttagttg
    22861 gaggaataca tgtatttatg ggaccactag ggtacttcac actaggcgca acaggaggtt
    22921 cactaattgt atctctagtt cttggatata taggtaagat aggggtagta aatttcagaa
    22981 tggaagaaaa ggttttaaat attttaaaac aaatagggct agtatttttc ttagcaatag
    23041 ttggattaag atatggtgga aaagtagttg attcaattat gacatctggt atgcacctag
    23101 ccttagtagc aatagcagta ggtgttacag ctatgatgat aggattctta gttggcaaat
    23161 acgtatttaa attaaattgg attttattat ctggagctgt ctgtggtggt atgacatcaa
    23221 caccaggtct tggagctgct gttgatgctc ttgatagtga tgacccagca gcaggttatg
    23281 gtgctacgta tccatttgca ttattaacta aagttatatt ggttatagtt ttacacaaac
    23341 ttccaatgta aataagattt tatatggggg gatatttatg aataatgaag gagcatttga
    23401 agaattaagt ggaagattaa gaaataaaga attgtgtgat ttaataatga atgcagatga
    23461 agctgctaaa attatagagg atggcatggt tattggagtt agtggattta caccttcagg
    23521 ctatccaaaa gcagtaccat tagcagtttc agaaagagct aaaagtggag aaaagataaa
    23581 attaaccgta tattcaggag catctttagg tccagaagtt gatggagcat ggtcagaagc
    23641 aggtataatt gaaagaagac ttccttatca aactaattca atacttagaa ataatattaa
    23701 taaaggtgtt gttgattata tagatatgca cctaagtcat tctactcaat ttttaaatta
    23761 tggaactata cctaaagtag atgtagctat agtagaagca cttgcaataa ctgaagaagg
    23821 aaatattata ccaactagtg ggataggtaa ttctccatct tttataaaaa gtgcagataa
    23881 agtaatagta gagataaatc ttgcaaaacc aatggaaatg gaaggtatgg cagatatata
    23941 tattacggaa aatccaccaa atagaaaacc aatagaaata aatcatccta aggatagaat
    24001 tggaacaaca tatatacctt gtggtttgga taaaattgca ggagtagtaa ttaccaatat
    24061 gcaagataag acccgtccat tgggagttgt agatgaagct tcgaaaaaaa tatcaaataa
    24121 tattattgct tttttaagag aagaagtaaa ggcaggcaga ttatcaaaga atttacttcc
    24181 tcttcaatct ggtgtaggaa gtgtagcaaa tgcagtatta tatggattat gtgaatctga
    24241 atttgaaaat ttaacttgtt atacagaggt tgtacaggac tctatgttgg atttaataag
    24301 aatgggtaaa gttacaatgg catctactac atctgtaagt ccatctccag aaggattaat
    24361 aaaatttgaa aaagatattg atttttttaa ggataagatt atattaagac ctcaagaaat
    24421 tagtaacaat ccagaaatag ccagaagaat tggtgtaatt gcaatgaaca ctgcaattga
    24481 agttgatatt tatggaaatg taaattctac tcacataatg gggtcaaaga tgatgaatgg
    24541 aattggtggt tctggtgatt ttgctagaaa tggagcaata actatattta gtactgagtc
    24601 aattgcaaaa aatggtgata tatcatcaat agtacctatg gtatctcacg tagaccacac
    24661 tgaacatgat gtaatggtaa ttgtaacaga acaaggatat gctgatttaa gaggtcttgc
    24721 acctagagaa agagctataa aaataataga aaattgtgcc catccagatt ataaagaaca
    24781 acttagggat tatttaaata gagcttgtaa aagtggagca aaacaaacac ctcacatatt
    24841 ggacgaagct ttatcatggc atagtaaatt tatgagtaca ggtacaatga aaaaggctga
    24901 aacttttaaa agtgcattat aaaatattta ataaattgga ggtagatttt aaatggaaaa
    24961 agcagtggaa aactttgaag atttaagtaa ggaatacatt aatggttata ttgagagagc
    25021 aagaaaagct caaagagagt ttgaatgtta tactcaagaa caagtagata aaatagtaaa
    25081 aatagttgga aaagtagtgt attataatgc tgaatattta gctaaacttg ctgtagaaga
    25141 gactggaatg ggagtatatg aagataaggt agctaaaaat aaaagcaaag caaaagttat
    25201 atataacaat ttaaaagata aaaaatcagt tggtataatt gatatagata gagaaactgg
    25261 aataacaaag gtagctaaac cagttggagt agtagcggca ataactcctt gtacaaatcc
    25321 aatcgttaca cctatgagca atgcaatgtt tgcacttaag ggaagaaatg caattattat
    25381 cacacctcat cataaagcaa ttggatgtag tacaaaaact gtagagatga ttaatgaaga
    25441 attagaaaaa ataggagctc cagaaaattt aatacaaata cttgaccaac aatcaagaga
    25501 aaatacaaga aatttaattt catcagcaga tgtagtaatt gccactggag gaatgggaat
    25561 ggtaaaagct gcgtactcaa gtggaaaacc agcacttggt gtaggggcag gaaatgttca
    25621 atgtatcata gatagagatg tagacattaa agaagcagta cctaaaatca tagcaggaag
    25681 aatttttgat aatggtatca tttgttcagg tgaacagtca gtaatagtag cagaagaaat
    25741 gtttgataaa ataatggatg aatttaaaaa taataaaggt tttatagtta gagataaagt
    25801 acaaaaagaa gctttcagaa atgctatgtt tgtaaataaa tctatgaata aagatgcagt
    25861 aggtcaatca gttcatacaa ttgcaaaaat tgcaggtgtt gagataccag aagatacaaa
    25921 aataatagta atagaagctg atggaccagg agaagaggat attattgcaa aagaaaaaat
    25981 gtgtccagtt atatctgcat acaagtataa aagttttgaa gaaggtgtag ctattgcaaa
    26041 agcaaattta aatgtagaag gaaaaggaca tagtgtatct atacattcaa atacagttaa
    26101 aaatatagaa tatgcaggag aaaatataga agtatcaaga tttgttatta atcaatgttg
    26161 tgctactagt gctggaggaa gtttctttaa tggtcttgca cctactaata ctctaggttg
    26221 tggttcttgg ggaaataaca gcatctctga aaatcttgat tataagcatc taattaatat
    26281 ttctagaatt gcttattata tgccagaaaa tgaagtccct acagatgaag aactttgggg
    26341 ataaaattta gacaaaaaat attcattcta aattaaagta ggaatatatt ttaatttaga
    26401 atgaatttaa gacataaatt aaatttaaat tagtttattg gactaaattt aaaatattaa
    26461 gagacatata gaagaaggaa gtattataat ttaaaataaa taaaaaaatc tataaaagag
    26521 aaggagtggt tttattatgg cattaatgac aggagctcaa tatattgaaa gtttgagaaa
    26581 attaaatact aaggtttata tgtttggtga agaggttaag aattgggttg accatcctat
    26641 gattagacca tctataaatt gtgtagcagc aacttatgac ttagctcatg acccagaata
    26701 tgcagattta atgacagtta cttcaaatat cacaggtgaa aaaataaata gatttggtca
    26761 tcttcatcaa agtgttgatg atttgataaa aaaagtaaaa atgcaaagac tatgtggtca
    26821 aaaaacagct tcttgtttcc aaagatgtgt tggtatggat gcgtttaatg cagtgtattc
    26881 aacaacattt gagtgtgata aagcccatgg aactaattat catgataatt ttgtaaaata
    26941 cttaacttat atacaagaaa acgatttagt agttgatgga gctatgactg accctaaggg
    27001 agatagaagt ctatcaccta gtgctcaacc tgacccagat atgttccttc atatagtaga
    27061 aagaagagaa gatgggataa ttgtaagagg agcaaaggca catcaaactg gttcaataaa
    27121 ttcacatgag caccttataa tgcctactat aagtatgact gaagcagata aagactacgc
    27181 tgtatcattt gcagttcctt cagatgctga aggagtgttt atgatttatg gaagacaatc
    27241 ttgtgacact agaaaattag aagaaggtgc agatgttgat ttaggaaata aggagtttgg
    27301 aggtcaagaa gctttagtag tatttgataa tgtatttgtt ccaaatgata gaattttctt
    27361 atgtggagaa tgggatttct ctggtatgtt agtagagaga tttgcaggat accatagaca
    27421 aagttatggt ggatgtaaag taggagtagg tgatgtaata ataggagcag cagctttagc
    27481 agctgattat aatggagcaa acaaagcttc acatataaaa gataaactaa tagaaatgac
    27541 tcaccttaat gaaagcttat attgctgtgg tatagcatgt tcatcagaag gtcacaaaac
    27601 agaagctgga aactatcaaa tagatttact tcttgcaaat gtgtgtaaac aaaatgtaac
    27661 tagatttcct tatgaaatag taagacttgc agaagatata gctggagggc ttatggttac
    27721 tatgccttca gaaaaagact ttaaatcaga ccttaaagtt ggaacaagtg gaatgactat
    27781 tggcgaagta tgtaacaagt attttaaagc ttcttcagtg gcttcaacag aagaaagaat
    27841 gagaatatta agattcttag aaaatatatg ccttggttca tctgctgttg gttatagaac
    27901 tgagtcaatg catggggcag gttcaccaca agctcaaaga ataatgattt caagacaagg
    27961 aaacataaat caaaagaaag aattagctaa gaaaattgcg ggaataaaaa aagaggaagc
    28021 tttaaattta taaaaagttg atatataaag ggaaattata tattaatgtg tgttaattaa
    28081 tgaaaaaata tgtagtataa gagatagtta taaaattatg gtggttttta gctaagtaaa
    28141 gaaattttta ataaggagaa tttacacatg acctgtggag ttagattttg tgggggctgt
    28201 aaccctagat acgaaagagg gaaggctctt acaataatca aagagcactt caatggtagg
    28261 gtagatttta gtatagcaca agagaacgtc gagtatgatt tgttacttat aattggagga
    28321 tgcgcaactc tatgcgcatc ctatcaacaa tataaagtga aaaatgaatg tgttaagatg
    28381 tgggatttta gccatataga aagagttata aatgtgattg aatcagcaat ttgtgaaact
    28441 taaaaaagct aaatgggggg atttcattga gttggcaaga attgtatcaa agtaaattat
    28501 gtagtgctac agaagctgta aaacagatta aaaacggtga tactgtagta tttgcacatt
    28561 gtgtaggtga acctcctgca ctagtagaag ctatgattga aaatgctgaa caatataaag
    28621 atgttgagat taaacatatg gtaagcttgg gtagtggtgg atatactgct aagggaatgg
    28681 aagctcattt tagagtaaat ccaatgtttg taagtggaaa tgtaagaaag gcaattgaaa
    28741 atggagatgg tgattttaca cctgcattct tccatgaagt accaaagttg cttagagaaa
    28801 aaagattaaa atgtgatgtt gttttagcac aggtaactcc accagatgaa catgggtatt
    28861 gtagcttagg aacatcagtt gattatactt atgaagccat taaaactgct agaacagtaa
    28921 ttgttcaagt gaatgaccag tttcctagaa cctatggtga ggtagtccat gtatcagagt
    28981 ttgactatat agtggaaaaa tcacaacctt tatttgaact acaacctgca aagattggag
    29041 aagtagaaga agcaattggt aaaaattgtg cttcattaat tgaagatggc tctactttac
    29101 agctagggat tggtgggata ccagatgcag ttatgttatt tttaactgat aaaaaggatt
    29161 tagggattca ttcagaaatg atttcagatg ggactttggc cctttatgaa aaaggtgtta
    29221 taaatggtaa atataaaaat tttgataaag aaaaaatgac agttaccttc ttaatgggta
    29281 ctaaaaaatt atatgacttt gcaaataata accctgcagt agaggtaaaa ccagtagact
    29341 atgtgaatca tccagcaatt ataatgaaac aacataagat ggtttctata aattctgcta
    29401 tacaagttga tttaatggga caggtagttg cagaggctat gggacttaga caatttagtg
    29461 gtgttggagg tcaagttgac tttatacgtg gagtgtctat gggtgaagat ggaaaggcaa
    29521 ttatagctat gccttcaata actacaaaaa aagatggtac agtaatttca aaaatcgtat
    29581 ctattgtgga tgaaggtgca cctataacga catcaagaaa tgatgttgac tatattgtaa
    29641 cagaatacgg tatagcagaa ttaaaaggaa aatctcttag agaaagagca agaaatttaa
    29701 taaatatagc tcatccaagt gtaagagaac atctagcagt agaatttgaa aagagattta
    29761 aggagaaata ttaataatag aggggtgtta ataatggaag cacttagagt agttccaaag
    29821 atattttact ttgatacatt taaagaattt aatgaagaat ttaaaatagg aaaaaatgat
    29881 ttagtaatta ctaatgagtt tatatatgag ccatatatga aacctcttgg aatagataca
    29941 aatttaattt ttcaagaaaa gtttggaaca ggtgaaccat ctgatgaaat gatagactcc
    30001 atgacaaagg aaatgaagaa atacaatttt gatagaatta ttgcatttgg aggaggaaca
    30061 atagttgata tatgtaagat attagcactt gatgttccag aaaagtctat tgatttattt
    30121 gaaggagaag tattacctaa aaaagtaaaa gagttagtag tagttcctac aacatgtggt
    30181 acaggtagtg aagtaacaaa tgtagctatt gcagagttaa aatctaaaca tactaaaaag
    30241 gggcttgcag tagaagaaac atatgcagac tatgcagtgt taattccaga gacagtaaaa
    30301 gggttacctt acaaattctt tgttacaagt tcggtagatg ctcttataca tgctattgag
    30361 tcttatcttt ctccaaaagc aagtccattt acagagatgt attctctaca agcaataaaa
    30421 atgattatgg atgggtataa gaagatagtt gataaaggag aagaagagag atttaatcat
    30481 cttagagact ttgtacttgc atcaaattat gcaggaattg cttttggaaa tgctggttgt
    30541 gcagcagttc atgcactatc ttattcaata ggtggagctt tccatgttgc acatggtgaa
    30601 gcaaattatc agttctttac tgaagtattt aagatgtatt ctagaaaaaa acctaatgga
    30661 aaaattataa aatgtacaaa aattttagca gatgcccttg aatgtgaccc taactgtgat
    30721 gtttatggag aattagaaaa gtttttaaat aaattaatag ctaaaaaagc tttgagagaa
    30781 tatggaatgg tggaaagtca gatagatgaa tttacagata gtacaatagc aaatcaacaa
    30841 cgactacttg ctaataatta tgtagagctt agtagagagg aaataagaga gatatttgca
    30901 aatctttatt aatacaattt tttatttata tgtatagtca acataaataa tgctaattat
    30961 atttatgtac aaataaaaat aagggaactt aaattttaat taaagttaag ttctcttatt
    31021 tttatatgga gttaaatata agtatatttt taatttaaaa tatgcttata tttaagtcta
    31081 ttactttatt tgaaacaatt tgtagaattt caaattcctt gacagtaata agtaagtaat
    31141 tgtataatca aactgcaata tattaataat attagtgaaa atgaaaggat tataaaatat
    31201 gtataaatca gaaaattttt caaaaaaatc tgtattaata aattcatttt taagtaaatt
    31261 tttaaaaata attggatggg gtttggtaag cttatttaca ttatcagcct tagtactttc
    31321 aactatttcc attataattg gatgggctgt aatacttcct attcaagtat gtgcagtatt
    31381 tttacttata ggaggagttt gtatttttaa aggtaagaga ttaggagacc aaatttctcg
    31441 ttataaaaaa tattgtacaa ttataaacaa tagaaatatt attccagtag aacttattgc
    31501 agaaaacaca tctaaatcat taaattttat aataaaagat gtacaaaaga tgatagacaa
    31561 aaactacttt ataaatactt atattgataa aagaaataat cagattgtgt taacaaatga
    31621 agattttatt ccaccaagat atgaagatgt agcatatgaa gtcaaagaag aagaaaagac
    31681 tgatgaatcc aatgaagttg atacaattat aaataaagga atgaattatc taacacaaat
    31741 aaaagaagct aataaaaata ttaaatcaga atcaatgggc aataaaattg tacaagtaga
    31801 agatgttaca agtaaaatat ttgatgttgt aaaacatgac ccatcaaaac ttactcaaat
    31861 acaaaaattt atggattatt atcttccaac cactttaaaa ctattaaatt catatcatac
    31921 attggaagaa caaggaattg atagagaaaa tataacaaca actatggaaa gtattgaaaa
    31981 tacaatgaat acgattgtag tagcttttga aaatcaattg gactatttgt ttgaagatga
    32041 agccattgat atttctacag atattactgt tttagagaat atgttagtcc aagaaggatt
    32101 aacgagtggt aaattttaac ttcaatagaa aaaatattct gttattttta aacaattaat
    32161 tagtcataaa gtataaaatg tgtattatat aagttaatca gtactttatg aaggaagagg
    32221 agagaaagat acaatgaata atttagatga tataccagtt atgccaactt tgacacttga
    32281 cccatttgga gaagaatcaa acactaatga tatagataat tctgacttat taatgaaaaa
    32341 ggatgaaaaa gacccagaag aagaaaaact gtctgaatct gaacgcaaga tggtaaagga
    32401 atttgcggaa aaaatagata ttacaaatac aaatatgatt ttgcaatatg gagctggagc
    32461 tcaaaaaaag gtagcaagtt tttctgaaac agctttaaag agtgtaaaaa caagagattt
    32521 aggagaagtt ggagatatgc ttacaaatct agttactgat ttaaaagcat tttcagcaga
    32581 tgaaaaagaa caaagtggtt ttttaggaat ttttaaaaag gcaaataata aaatttcaaa
    32641 tttaaaaact aagtatgata gtgcagaggt aaatgtggat aaagtaagta aagagcttca
    32701 aaagcatcag gttaaaatat tgaaagatat agcaatgctt gataagatgt atgaattgaa
    32761 cttagcttac tcaaaagagc ttactatgta tattatagca ggaaaacaaa aattaaagga
    32821 tatgaaagaa tatgagatgc caaagttgag agaaaaagct cgtttatctg gttcaacaga
    32881 agatgctcaa tctgtaaatg atatggtttc actttgtgac agatttgaaa agaagattca
    32941 tgacttagaa ttaactagaa tggtatcgct tcaaatggct cctcagataa gattggttca
    33001 aaatagtaat aatctgatgg cagaaaagat tcaatcaact atagtaaata ccattccatt
    33061 atggaaaaat caaatagtgc ttgctcttgg aatttctcac ttaaatcaag ctatgaaagc
    33121 acagcgtgaa gttagtaata tgacaaatga gcttttatta aagaatgcag aaactttgaa
    33181 gataggaaca atagaaacag caaaagaatc agaaagagga attgtagata tagacacaat
    33241 taagaaaact aatcaatctc taatatctac tattgatgag gtagttaaaa tacaacatga
    33301 tggtagaata aagagacaag aagcagaagt tgaattatca aaaatagaaa atgaacttaa
    33361 aagtaaactt cttgaattta cagttaaata aaaattatac taatataaaa agagactgtc
    33421 tcaaaataga gataagtctc tttttcattg tttaaatgat taaagtatat ttatattata
    33481 aatttctatt atcttttaac ataacatcat gagctccacc ttcaactata ctagtagaag
    33541 atacaagtgt aagtttagca tttttttgaa gttcaggaat gctaagtgct ccacagttac
    33601 acatagtaga acgaacttta cttaaagaaa gagttacatt gtctttcaaa gaaccagcat
    33661 aaggcacata agagtcaaca ccttcttcaa aagaaagttt cttatctcca ccaaggtcat
    33721 atctttgcca gtttctagca cgagcagaac cttctcccca atactctttc atataactac
    33781 catttatatt aactttgtta gttggactct catcaaaacg agagaagtat ctaccaagca
    33841 ttataaaatc tgcacccata gctaaagcta aagttatatg atggtcataa acgataccac
    33901 catcagagca aattggaata taaatacctg ttttttcaaa gtattcgtct ctagcttgag
    33961 caacttcaat tatagaagta gcttgtccac gtcctatacc tttttgttca cgagttatac
    34021 atatagaacc accaccaata ccaactttaa cgaagtcagc accagcttca gctaggtaaa
    34081 ggaatccttc gcggtcaact acatttccag ctcctacctt aactgtatca ccatattttt
    34141 cacgaatgaa atcaagtgtt attttttgcc actcagaaaa accttctgaa gaatctatac
    34201 ataaaacatc agcaccagct tcaactaaag caggaacacg ttcagcaaag tctctagtat
    34261 taataccagc tccaactaca tatctcttag aagaatctaa aagttcaagt ggattttctt
    34321 tatgagaaga gtaatcttta cggaatacca tatacataag attaccatta tcatcaagta
    34381 caggaagaga attaagtttg tggtcccata taatattgtt tgcttccttt aaagtaacat
    34441 ctttgttagc ataaactata gatgacatag gagtcataaa ttcactaact ttagtatcta
    34501 aatccatacg acttatacga taatcacgac ttgcaacaat acccaataat ttaccagttg
    34561 aagttccatc ttcagtaaca gctactgtag aatgtccagt tttttctttt aagtcaagta
    34621 tgtcttttaa tgtgttatca ggtttaatat ttgaatcact tacaacaaaa ccagctttgt
    34681 gggatttaac acgtgctacc atagcagctt cattttcaat agtttgagaa ccgtatataa
    34741 atgaaatacc accttcttta gcaagtgcaa tagccatttt gtcatcagaa acagattgca
    34801 taatagcaga agtcaaaggt atattcatat aaatatctgc ttcctcgccc tttttaaatt
    34861 tagtaacagg tgtttttaaa cttacattag caggtataca atcagtagaa gagaaacctg
    34921 gtacaagaag gtattcactg aaagtatgtg atggtgtatc aaaataaaac gccatttttt
    34981 aatcactcct tatattttta tactttttat aattgatagt attaattata acttattctt
    35041 taattttatt aaagtatttt gtcaaatatt gagatttttg aaaaatttaa actattttaa
    35101 ttaaatttgt ttaatatata ttgccctata gggtaaagtt gtatattaaa taatgtttag
    35161 tgtttaatag tagctaattt aaaattaatc tttagtgatt catataatta catttgtata
    35221 gtttacattg ataatattac tagagagtgc ataaacctca aaaatacaga taaattaaat
    35281 ctatattagt atatccaaaa gtacatttaa taaatttatt taactgaatt attattttca
    35341 tttctattaa atttaaatat tttataaaaa tagtattatt tacaaaatca tatactccaa
    35401 aatactacat aaataaaatt aaacaaaaac taaaatgaca aatgtcatta tctaaagtga
    35461 catagaaacg gtttcttaaa gttgttacta taaaatataa actctataat aaaagtataa
    35521 caaaagggaa tcatatcgat atagaatata attcaagagg aggtaaaatt atgagtagtt
    35581 ctaatcaatc gacaataaag acatctatac agcgagtagg gaaattttta agtggtatgg
    35641 taatgccaaa tataggagct tttatagcat ggggtcttat aacagcatta tttataccaa
    35701 caggatggat gcctaatgaa aaattgagta ctataggtga cccaatgata aaataccttt
    35761 taccactatt gatagcttat actggtggta aagcaatagc aggacaaaga ggtggcgtaa
    35821 taggtgcagc agcagctatg ggagtaattg ttggtgcaga tataccaatg tttatcggag
    35881 caatgataat gggaccattt gcaggatggg taattaagaa gtttgataaa tttgtagatg
    35941 gaaagatacc aacaggattt gaaatgttag taaataactt ttcaataggt ataataggta
    36001 tgcttcttgc aatactagga ttttatgcaa ttggaccagc aatagtagca gggacagctc
    36061 ttatagaatc tggagttcaa tttatagtta gcaaaagttt attgcctcta gtttcagtat
    36121 ttatagaacc tggaaaagta ttattcttaa acaatgcaat aaatcatggt atattagggc
    36181 ctataggtat agctgaggca aaagaagcag gtaaatctat aatgttctta ctagaaagta
    36241 accctggacc aggtttagga gttctattag catattggat gtttagtaga ggaagtgtaa
    36301 aacaatcagc accaggagct gtaataatac atttctttgg tggtatccat gaaatttact
    36361 tcccatatat tttaatgaat ccagttttaa tattggctac aatggcaggt ggagcagcag
    36421 gaatattgac tttttcaata ttaggagctg ggcttgtagc agcaccatca ccaggaagta
    36481 tatttgcact tatggcacta gctccaaagg gaggattact tccagtatta gcaggagttg
    36541 cagtggcaac agttgtatca ttcttagtgg cagcaccatt tgttaagaga gcttcagcaa
    36601 atcaaagtga agaagacagt acttctttag aagaagctaa agcaaaaatg agtgatatga
    36661 aatctgcaag taagaactct gagaaaaata ttgaggaaaa acagcttgaa gtaaatgaga
    36721 ttaagaagat tgtatttgca tgtgatgcag gaatgggttc gagtgcaatg ggagcttcca
    36781 gatttaaaaa tagaataaaa aacttagact taaatataga aattacaaat tcatctgttg
    36841 ataatcttcc aaatgataca caaatagtag taactcacaa tacattagtt gaaagagttg
    36901 ctaagaataa ttcaagtgtt gagatagttt caataaacaa ttttttaaat gacccaaatt
    36961 tagatgcatt atttaaaaga ttagaatcta aataaaaata aaaagtacca ctaattagga
    37021 gtggataatt tgaaaaaaaa gaagattaca tctaggcaaa aaaagataat actaatgata
    37081 gtagaaaatt caaagaaaaa cattccaata actatttctg agattgcagg gactttagag
    37141 ttaagttcaa gaactgtact tagagatatg tctggaattg aaaaatggtt tgatgaaaat
    37201 gattttaact ttgtaaaaaa accaggagtg ggattgattt tagaggaaaa tatagaaaat
    37261 caaaacttta taattgagtt gttagaagaa gaaaaaatag aaaaagaata cagcaaagaa
    37321 gaaagaaatt taattatatt atcaaagcta ctagtttcta acgagccagt aaaatcctat
    37381 tattttgcaa aaatattaaa ggtatctgaa ggggtactga ataatgattt tgccttagca
    37441 agtaaatggt tggaaagatt tgatattgag cttgttagaa aaccagggct tggtgtctat
    37501 ttaaaaggtc aagaaaaaag ctttagagag gcatatgtaa atcttatata cgattcattc
    37561 aatgaaaaag aaatactaga tatggtcaga aatataagtg aaaatataca aacagataaa
    37621 gcaatagaaa ttttaagtga aaatagactt ttaaatttaa tagacaggtg cataataaga
    37681 aaagttgaag ctacattaac aaagaagctt tcagatttag atgtaaattt agctgatagt
    37741 gcatatatag ggcttgtagt tcatatttca ttagccttac agaggataaa aaatggtgaa
    37801 aatataacta tggataaaga gtttctaaaa gaattatcta taacagaaga gtttaaatta
    37861 gctaaagaaa tcgtaaaagg tatggaaaca gattttaaca tggatatacc agtagatgag
    37921 gttggatata taactatgca tataagaggt gcaaagcaaa ggtcatcttc aaaccataag
    37981 gctttaaact tagatgatat agaaataatg gaaattacaa ataagatgat agatttggcg
    38041 gaagatgaat ttaaaataag tttaaaaaat gacgagaggt tatttaaaga cctagcaaat
    38101 cacttagggc cttctataaa tagattgaat atgggattag aaataagaaa tcctctttta
    38161 gatgaaataa aaagcaagta ttcatatgcc tatgatggag ttgaaaagat ttctagaatt
    38221 ataaaagata aactaaatat aaattcaata cctgaatcag aaataggata tattgcaatg
    38281 cactttgcat cagccataga aaaaaatctt atgatgaata ctaatataaa tattgttgtg
    38341 gcatgtcccg ctggaatagg tacttcaaga ttcttatcaa ctaagattga aaataaattt
    38401 cctaatttaa atatacttga aaccatatca gctataaaca tagatgaaga gtatttaaag
    38461 gaaaaagatg ttgatttaat agtgtctaca gttgagttaa atacaagttt aaattatata
    38521 tgtgtaggtc catttatgag tttagatgat gaacagataa tcaaggaaaa aataaaatct
    38581 atagctcaaa ataaattaat caatttaaat gcgaaaaatg atactaagag taagaataaa
    38641 gtatatgaac agataacaga aagtatgaat ataggaaaag atattcttca atttttagag
    38701 gaaattagat ttgaaaaatt tgaaagtaaa gatttaagtg agcttattga agactcatca
    38761 aaaatatttg caaaatctag tgaagatata atctctataa aagaatcgtt aaaagaaaga
    38821 ttaaaaattt caattccata tatagaagaa tcaaaaattc tattgttaca ttgtatgagt
    38881 gaaagaatag atattatgaa gttatcaata ataaaactag agaatagaat cgtgctagat
    38941 tcaaatgaag aaatcgacaa tgtagttttt atgttacttc ctaaaaattc accaagttat
    39001 caaagacaaa taatgagtga aataagtggt tcattaatag acaatataat ttttactaat
    39061 aagataaata aattctctat agaagagatg gcattagagg taaaagatat agtttttaat
    39121 ttttatacaa acagattaaa agcatttata gataaataaa attaatatta aaaaggaagg
    39181 ttgatactat gagtaaagta ttgaatgaga ataatatatt tttagggtta gatagtgttt
    39241 caaaggaaga agctataact ttagcaggaa gaaaattagt tgaaaatgga tatgtaaaag
    39301 aagaatatat accagcaatg ttagaaagag aaaaagtaat gactacatat atgggaatgg
    39361 gagttgctat tccacatggt gtaaatgaag caaaaaaaga aatattatct tctggaatag
    39421 ttatattaca attccctaat ggtatagatt ttgatggaga aaaagcatat ttattaatag
    39481 gaatagctgg tgttggagat gaacatttag aaatactatc taatatagca gtagttttag
    39541 atgatgactt aacagaaaga ctaaaaaatt caaatgacaa acaagctttt atggaagctt
    39601 ttgccaacta atcttaggag ggatttaaaa tgaaaaaggc aattcagttt ggagcaggaa
    39661 atattggaag aggttttatt ggaggcttgt tagttaagtc gggttatcat gtagtatttg
    39721 ctgatgtaaa tgaggatata ttaaactcaa taaacaaaga taaaaagtat actatacaca
    39781 taagagatgt agaatgtata gatgaagtaa ttgataatat aagtgcggtt tcatctataa
    39841 aagaagaaat aatagatgag attgtacagg ctgaaataat aactacagca gttggacctt
    39901 tagttttgac taaaatagct tctacaattg caaaaggtat aaaagctaga aaagaaaagg
    39961 gattaacaag taatctaaat ataatagcat gtgaaaatgc aatatacgca agttcttctt
    40021 taaaagaaga ggtacttaag tatttaaata aggaagaagt agaatattta gagatgtatg
    40081 ttggttttcc aaactgttca gttgatagaa tagttcctcc tggtaaaaac gaaaatcctc
    40141 ttgatgtaac agttgaaaat ttttatgagt ggaatgttga aaaacaagga tttaaagggg
    40201 aaataccaac tatagttgga atgaatttag ctgataatct tatggcttat atagaacgta
    40261 aattgtttac actgaataca ggtcatgcta taacagctta tataggatat ttaaaaggat
    40321 ataagactat agaagagagt ataaaagata aatttatctg tgatatagtc aaaagtgcaa
    40381 tggtagaaag tggagaagga ttgattaaaa aatacaattt tgactcagaa gtgcactata
    40441 aatatattga taaaatttta aatagattta aaaatccata tcttaatgat gatgtattaa
    40501 gagtcggaag ggaaccatta agaaaactaa gtgataaaga tagattgatt aaacctttaa
    40561 tgacagcaaa atcatatgga ttatcagttg ataatttgat tcttggaata ggtgcagcgc
    40621 ttcattataa taatagtgaa gatactcaaa gtgtagaatt acaagagttg ataaagtcta
    40681 ttggagtaaa aaaagccgtt gctaaaatag ctaatataag caatgacgaa gaacttttaa
    40741 ataatatcga aaaaagttat atatttatga aaaatttata aatttacttg aaaaaaagta
    40801 gttctgataa agtaactata atatattatt ctacacagtt tgaattattt gttgaataat
    40861 agagaattat aatatataat taaaaggaat aaattaatat atttacctgt atatgtttga
    40921 taatatggtt caaatgtttc tactaagcta ccattaatag cttgactaca ggagtgaaga
    40981 agatatagtt tatacttatt ttaaattata tattaagtta attactttga attttaagct
    41041 cctgtctatg atatagacag gagctttttt agtattttaa tataaaatac ttacaagaat
    41101 agatagcaaa attagaacaa atataatttt tttattaata taattttaga aagggctagg
    41161 tggaagttca atgaaggctt tacaagaaaa gatattgaga gaaggcagtg tttcaggaaa
    41221 tgatatacta aaagttgata gttttttaaa ccatcaaatt gatgtagctt ttttaaatga
    41281 aataggaaga gaatttaaag agagatttaa aggagaaaag gtggataaga tatttacaat
    41341 agaggcttca ggaatagcta tagcatcaat tgtttcacag tattttgata atgcacctgt
    41401 agtatttgca aaaaaatcag aatctaaaaa tttggataaa gatgtatatg aaactaatgt
    41461 atattcattt actaaggcaa gagagtattc agttaaagtt tctaaaaagt acataaacaa
    41521 aggcgaaaat atattgatag tggatgattt tttggcaaat ggaagagctg ctcttggact
    41581 taaagattta attgagcaag cagaagctaa cttagttgga gtaggaattg tcattgaaaa
    41641 aggatttcaa gctggaggag cacttttaaa ggctaatgat gtaagattag agtctttggc
    41701 agtagttgaa tctatagata atggaactgt aaaatttagg taatttatga tatcatatac
    41761 ttgtgtttag cacatatttt aactatgtaa ttatggagga ttttttatga gattttttat
    41821 agacacagcc aatattgaag aaataaaaga agcaaatgat ttaggtgtaa tctgtggtgt
    41881 aactactaat ccgtctctaa tagctaaaga aggtagagat tttatagagg tagttaaaga
    41941 aataagtgaa atagtagatg gaccaataag tgcagaagta ataagtttag aacataaagg
    42001 tatgatagag gaagcagaaa aattatctaa gatacataaa aatatagtta taaagatacc
    42061 tatgacagca gaaggtctaa aagcggtgaa agtactatca agtaaaggta taaagactaa
    42121 tgtaacgctt atattctctg ctggacaagc tcttttagct gctagagctg gagctacata
    42181 tgtaagtcct tttgttggta gattggatga tatatcacaa aatggtcttg atttaattga
    42241 agaaatcgtt gatatattta gtgtaaatag tattgaggct caaataatag ttgctagtgt
    42301 tagaaatcca atacatgttt tacaagctgc tagaatggga gcagatatag caacagttcc
    42361 tcttaaagtt ataaaccaaa tgattaagca tcctttgaca gacaaaggaa tagatagctt
    42421 tatgaaggat tgggaaggtg cttctttaaa attataatta taaactacgc tttataagta
    42481 tattaaagag gttattatgg aaattctaag taataaggct aggctatttt gcctagtctt
    42541 attttggtgt ataatatatt gaaacatatt attgaaatag attaattttt taagtgagga
    42601 ggcgaaaaat ggataaaata ttaagagaga tacaaagaga agataaaaaa aatccatata
    42661 ctgaccaaga acttgctgaa atgttaaatg tagctaggtc tgaagtgata tcagttagga
    42721 aaaaaaataa tattttagat tcgagagaaa gaagaaaaaa aatattaata aaagatatat
    42781 caaaaattgt aagtgaaaat cctcaaatgt ctgaaagaaa aataactgaa atattaatag
    42841 aaaatggata taatatatcg agaagtgcag tttcaaaatt attaaaagag gaaaatttaa
    42901 atcagtcaaa gattgggatt aaggataaag acccagcatc atcaggaaag tatgtgaagg
    42961 tgagtaaagt tgtagaagaa gatggatttg aagaattgat aggtataaag ggaagtttga
    43021 aagaaaaggt aaatttagct aagtcagcaa taatgtatcc tcctaatggc cttcatacta
    43081 taatatatgg agaaacagga gtaggtaaaa gtgaattagc tacatgtatg tataaatatg
    43141 ctataaaaaa caacattaaa gaagagaaca gcccatttat agtgtttaac tgtgcagact
    43201 atgcagaaaa tcctaatcta ttgatagctc aactctttgg ggtagtaaaa ggtgcatata
    43261 caggagcaga tgcaaataga gaaggtcttg tagaacaagc taataatgga atattgtttt
    43321 tagatgaaat tcatagattg cctgctgctg ggcaagaaat cttattttca ttaatagata
    43381 gaggagaatt tagaaggtta ggagaaagta gttctaatag aaaggcaaat gttctcataa
    43441 taagtgctac aacagaaaat ccagattcta atttacttca aacatttaga agacgtatac
    43501 caatggtaat aaatttacct aatatgagtg aaagaccaaa atctgaaaga tatgaaataa
    43561 taataaagtt ttttgaaaga gaagcaaagc gagtaaacaa gaattttata ataactaaag
    43621 aagttatgtg tgcacttatg aattataagt gtactggaaa tataggtcag ttaaagagtg
    43681 atatacaagt aacttgtgct agagctttta gtaaatcgat attttctagt gataaagtaa
    43741 ttatagattt agatagttta agggattata taaaaagtgg atattatgat tgtaattgta
    43801 aaaatgaaaa gtattctgag ttttcagttg aggatatata tatagatatt agtgaattgg
    43861 tgagtggaaa aaatagaatt ttatctgata atgagataag cgagatatat aattatgcag
    43921 aaaaagagct taaggttttg gaaagtaagt gcttttcaga agaagagtta aaaaatgcat
    43981 ttatagaaaa gttagataag aagtttaatg ctattaaaaa caataaaaat ttatctgata
    44041 gaagaagtcg aatagactgg ggaggacaat taaaagagtc tacactggag ataatggata
    44101 aggtaattgt atttattaag gagcagttta agcatgtaaa tcaagggctg tacttggctc
    44161 tagcaattca tattgagcat gctataggta ggataaaaga tggaaaaact ataataaatc
    44221 cgagtttaga taaaataaaa gcatcaatgc caatggaata tgagttgtca agatatataa
    44281 tgggtatagt agaagatttg acacaagtaa catttccaga agatgagctt ggatatttgg
    44341 cttattatat aaataaattt tgttataatg aggaaagtat aaaagataaa gttaaagtag
    44401 taatagttac gcatggtaaa gttggaattg aaatgtctaa agttgtaaat catattttag
    44461 gtatagaatg tacactaggt atagaaatag cacttacaga ttcaccatca gaggggatag
    44521 agcatgtatt agaagagctt caaaagatag aagctagaaa aggtattcta gttctaattg
    44581 atatgggttc tttggtaatt cttggtgatg aggttgaaaa aaggcttgga attagatgta
    44641 aaactgtaaa tagagtagat acattattgg caatggaagc aggaaaactt gcaaccattg
    44701 aagggaaaag tttagatggt ataatagctg atttaaagaa aaataagaat tatgctatga
    44761 taaatacaaa taaatttagt tacagaaaaa acgagtatgg aaagaaaaat gtaatcatta
    44821 ctttatgttt gagtggtgta ggtacagctt taaatttaaa agagcatata gaaaaacaaa
    44881 ttaaggaata tgacacttta attgaagtaa agccagttgc ttttttaaat aataatttag
    44941 aagaagagtt aaatgatatt gaagctgaat ataatattat tgctatctgt ggaactattg
    45001 atatagatta taaaaacgtg ccttttattt cttataatga ggtacttggt aaaaatggta
    45061 ttaataaagt attagagcat ttaaatagta aacaaccagc tttaaatatt gaaaaccagt
    45121 tgaataattt aatacatgaa gatttgattt tatacaattt tgaaggaatt tcaaaggagt
    45181 atataattga tactcttgtt tcaaaacttg aagaaggtgg atatgtcgac tcaaagtata
    45241 tattaagtgt atataaaaga gaagcaatgg gaagtgttgt aatggcctct aaggtagccg
    45301 tgccacatgg acttccagaa aacgttataa agcctgcaat agcaattgcg aggttgaata
    45361 aacctatagt atgggacaat aaatttatgg tggatttggt ggtactactg gcacttaaag
    45421 aaaataataa gaaagaaata cgaagcttat tttcaaagat taatgaccag catactttag
    45481 aagttttatt aaatactgaa gataaaaatg aaataaaaga acttttaagc taattgttag
    45541 taccgagaag aaagacaaaa aaatttgctt tagtagtata aaatttaaaa ctactcaatt
    45601 gctaagtagt taattactct atataaggct agttctatga aatttattta tatgatttta
    45661 tagaattagc ttttttcttg gtaaataaaa tatatgaatt tatttatgta aaaagtaaat
    45721 tttattggac aattctataa aaatttttc
//
LOCUS       DAEPXW010000026        45605 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.026, whole genome shotgun sequence.
ACCESSION   DAEPXW010000026 DAEPXW010000000
VERSION     DAEPXW010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45605
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.026"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            93..731
                     /locus_tag="KRM55_001364"
     CDS             93..731
                     /locus_tag="KRM55_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593613.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(1220..2980)
                     /locus_tag="KRM55_001365"
     CDS             complement(1220..2980)
                     /locus_tag="KRM55_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1593614.1"
                     /translation="MQEVEVIKAKNVLARQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVFTKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCIGYDYHPEDKTITVNQEEAEIVRYIFNRYVDGAGGS
                     VIGQELESLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGGTLTRRNWHSGSKYSKVIWQCVTATKKGKKFCKHSKGIPETAIEEAFVESYRLLC
                     DDNKDVLEEFLQRMDDTLSSSVVSKQLAKAEKEIDALEKKKSKLVDMRLEEIIDKETY
                     ESKYADLVSKQEQLVEERQKLQETSDNEKDIKKRLKEFKKTLEQNEVLDKFDRYVFES
                     IVEKVIVGGLDENGNVDPAQLTFVYKTGLKNSVDGAKFKTQRKNARGRHRTNELCSHD
                     SNEVDKMCSDSSNDTCGNCS"
     gene            complement(3043..3186)
                     /locus_tag="KRM55_001366"
     CDS             complement(3043..3186)
                     /locus_tag="KRM55_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1593615.1"
                     /translation="MNNIIRYSMQIAMLKQLLARKLISEKEYTLVKQRLMKDYKVLSD
                     ITA"
     gene            complement(3505..3744)
                     /locus_tag="KRM55_001367"
     CDS             complement(3505..3744)
                     /locus_tag="KRM55_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1593616.1"
                     /translation="MMKSTKKCPSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVLDMELKGRIRAALIKVILGFEVKVK"
     gene            complement(3749..4165)
                     /locus_tag="KRM55_001368"
     CDS             complement(3749..4165)
                     /locus_tag="KRM55_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1593617.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGAMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            complement(4162..4461)
                     /locus_tag="KRM55_001369"
     CDS             complement(4162..4461)
                     /locus_tag="KRM55_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1593618.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEHNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFAVGYQIPPFMVSVSAKRGRSLFALATFAGKGVRL"
     gene            complement(5512..5679)
                     /locus_tag="KRM55_001370"
     CDS             complement(5512..5679)
                     /locus_tag="KRM55_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593619.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            complement(5692..8457)
                     /gene="mgtA"
                     /locus_tag="KRM55_001371"
     CDS             complement(5692..8457)
                     /gene="mgtA"
                     /locus_tag="KRM55_001371"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH1593620.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNRRIQFAATNPIKEVLKKLHT
                     TLRGLEVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKARV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            complement(8623..8934)
                     /locus_tag="KRM55_001372"
     CDS             complement(8623..8934)
                     /locus_tag="KRM55_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH1593621.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            complement(9181..9858)
                     /locus_tag="KRM55_001373"
     CDS             complement(9181..9858)
                     /locus_tag="KRM55_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH1593622.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            complement(9996..10499)
                     /locus_tag="KRM55_001374"
     CDS             complement(9996..10499)
                     /locus_tag="KRM55_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1593623.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            complement(10515..13178)
                     /gene="mgtA"
                     /locus_tag="KRM55_001375"
     CDS             complement(10515..13178)
                     /gene="mgtA"
                     /locus_tag="KRM55_001375"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH1593624.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGVIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGIYTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLNSVAKYFYKKKYQELI"
     gene            complement(13271..13480)
                     /locus_tag="KRM55_001376"
     CDS             complement(13271..13480)
                     /locus_tag="KRM55_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593625.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRERYEKMLAVSICAPNLEGM
                     VENFDKDLSRPNETDLIELKNAISK"
     gene            13430..13765
                     /locus_tag="KRM55_001377"
     CDS             13430..13765
                     /locus_tag="KRM55_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593626.1"
                     /translation="MTHMSADKLLLGFHLDHVSNLNELLRKVAHNNICIMSDRMTKVA
                     VWKPSVKTIQLVCMEYLNYIIDHSVIYEKIQCANWNGTEETNSIFNNSPSPLITLIYS
                     CDLQQNKTT"
     gene            complement(13964..14866)
                     /locus_tag="KRM55_001378"
     CDS             complement(13964..14866)
                     /locus_tag="KRM55_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1593627.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIDARTQAISG
                     YLTKELQDLNMDTIRTDIPTSSAITDVIVWSIEQSGTDTFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDAGGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKESNWKIIG"
     gene            complement(14883..15890)
                     /locus_tag="KRM55_001379"
     CDS             complement(14883..15890)
                     /locus_tag="KRM55_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1593628.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPSS
                     LDTESSIKQGCKYFASLLSSCKNQDIDDLNVAIQSYNYGGGYVGYVAGNGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVFGGSSPTTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYTDLSSSYWQQHLIGAGRVK
                     Q"
     gene            complement(15887..18091)
                     /locus_tag="KRM55_001380"
     CDS             complement(15887..18091)
                     /locus_tag="KRM55_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1593629.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFSSTGFYVGFLLLIIL
                     VVGMYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVQQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQHKKSIAVKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTVSKTGAEKMQEVKRPATTPTTKASEPVKTSGVKERPLSSSTPDGKATQSTYR
                     QNVEKVTVSKETRQNYTKDRRTKVQQTQTVQKNQQTTEKIRNLVTKKGQKKK"
     gene            complement(18091..20541)
                     /locus_tag="KRM55_001381"
     CDS             complement(18091..20541)
                     /locus_tag="KRM55_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1593630.1"
                     /translation="MFLIKYIDNNLVWNKDNEVFAYYEMIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNVIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPVGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSVYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(20519..20917)
                     /locus_tag="KRM55_001382"
     CDS             complement(20519..20917)
                     /locus_tag="KRM55_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1593631.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(21035..21538)
                     /locus_tag="KRM55_001383"
     CDS             complement(21035..21538)
                     /locus_tag="KRM55_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1593632.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            complement(21556..22059)
                     /locus_tag="KRM55_001384"
     CDS             complement(21556..22059)
                     /locus_tag="KRM55_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1593633.1"
                     /translation="MQETRVLVETGRTNGEETTSYWFDLPIDVAEFEEKLGVGAESQD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSADMQEEYVELLTVFENLEALYICR
                     NVITVYHDCKSMIDVARQKLMNDPTFKHLSEDCQAYYFDFEAYASHLLENKRYLVTEN
                     SIFELPE"
     gene            complement(21978..22274)
                     /locus_tag="KRM55_001385"
     CDS             complement(21978..22274)
                     /locus_tag="KRM55_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1593634.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     EDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGYWWKREEQMAKKQHHTGLTYR"
     gene            complement(22373..23146)
                     /locus_tag="KRM55_001386"
     CDS             complement(22373..23146)
                     /locus_tag="KRM55_001386"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593635.1"
                     /translation="MKGIKVLMISDEMRVDILHAVFINKNFIKDEENCNYEKYLLELV
                     NKSIYFREKSNFAEYVPPKSENHGECDCNSPNYQMDFKLLESTTRLHASKELTGQIQK
                     FCDGVIGKCPPRRPNTQMTVTRLFASLRDYDCESLHSCLTEKYEYGTIEFDIQTYVKL
                     LTFKKNLFFFFPYKFSFNTCYNFKYALDSIRIALEKDFRESNFFREKYYAEYDTFLAY
                     IYEDNLIISKFEQDGKLQMIDCIYLFKSQTYSKLYEYTW"
     gene            complement(23206..23427)
                     /locus_tag="KRM55_001387"
     CDS             complement(23206..23427)
                     /locus_tag="KRM55_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593636.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(23428..23562)
                     /locus_tag="KRM55_001388"
     CDS             complement(23428..23562)
                     /locus_tag="KRM55_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH1593637.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILSIGKEADYEMKQLEESEDN
                     "
     gene            complement(23575..24771)
                     /locus_tag="KRM55_001389"
     CDS             complement(23575..24771)
                     /locus_tag="KRM55_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1593638.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LIDGGIMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKYYQSGELIKHREDDR
                     EYMGSTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFIDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQAILSEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(24956..26350)
                     /locus_tag="KRM55_001390"
     CDS             complement(24956..26350)
                     /locus_tag="KRM55_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1593639.1"
                     /translation="MRMILNKGHRIRASDKNLVYRFSMGTLLFVFVAVILLLNTKQLM
                     RTDWEHFSLLDNGFTLSLYNFITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSVFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEQMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGFLAQARQ
                     DGTATCEAKGDGSD"
     gene            complement(26444..26881)
                     /locus_tag="KRM55_001391"
     CDS             complement(26444..26881)
                     /locus_tag="KRM55_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593640.1"
                     /translation="MCEECYSDENRITPLLNPLDCLENHTQYICGTCGRCICIEHDPN
                     RGLQRWNFPFKSLEIAKLYLRTADYTTKSSCGIYEIENSKGRVSYKIFAGNEDLHLFL
                     KKNKDKKCKQMTPVFNVGEYKEYPHTEVRKLTSDEIKQYMSER"
     gene            complement(26983..27366)
                     /locus_tag="KRM55_001392"
     CDS             complement(26983..27366)
                     /locus_tag="KRM55_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1593641.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNTGTSQNHTPQGQPKK"
     gene            complement(27382..27708)
                     /locus_tag="KRM55_001393"
     CDS             complement(27382..27708)
                     /locus_tag="KRM55_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1593642.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRKVIARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDVGHTDYVLVADDI
                     VAVEEK"
     gene            complement(27834..30878)
                     /locus_tag="KRM55_001394"
     CDS             complement(27834..30878)
                     /locus_tag="KRM55_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1593643.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPSTAVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASTRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDKNGNTDVVEVKAGTVYIRELSAPAGYKVDTT
                     VYSLKVEAGKTATLNVSDTPKVTDTLIELFKIDMETQKDNPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLSVEETKAPNGYLLDGAYMQAGDKSEQIKGLYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETSDTKPQGSATLKDTAFDVISLNDNSVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGKFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSAEWTSHK
                     HNTNAGKTSEDGVWFGTSEADDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDSEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFIADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKEIEAGKDVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKAEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDEGQTITFNEKPEVPEKLETPQTPEKPN
                     RPSDSPKTGDSTNVMAFLVMLLTSAGGLAGTYLYKRRTMKKS"
     gene            complement(31121..32485)
                     /gene="rlmD"
                     /locus_tag="KRM55_001395"
     CDS             complement(31121..32485)
                     /gene="rlmD"
                     /locus_tag="KRM55_001395"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH1593644.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHIETCVLLQ
                     RRTM"
     gene            complement(32660..34420)
                     /gene="pyk"
                     /locus_tag="KRM55_001396"
     CDS             complement(32660..34420)
                     /gene="pyk"
                     /locus_tag="KRM55_001396"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBH1593645.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(34472..35431)
                     /gene="pfkA"
                     /locus_tag="KRM55_001397"
     CDS             complement(34472..35431)
                     /gene="pfkA"
                     /locus_tag="KRM55_001397"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH1593646.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(35640..39209)
                     /locus_tag="KRM55_001398"
     CDS             complement(35640..39209)
                     /locus_tag="KRM55_001398"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBH1593647.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(39366..40313)
                     /gene="whiA"
                     /locus_tag="KRM55_001399"
     CDS             complement(39366..40313)
                     /gene="whiA"
                     /locus_tag="KRM55_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBH1593648.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(40330..40755)
                     /locus_tag="KRM55_001400"
     CDS             complement(40330..40755)
                     /locus_tag="KRM55_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1593649.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(40824..41930)
                     /locus_tag="KRM55_001401"
     CDS             complement(40824..41930)
                     /locus_tag="KRM55_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBH1593650.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(41942..42799)
                     /gene="rapZ"
                     /locus_tag="KRM55_001402"
     CDS             complement(41942..42799)
                     /gene="rapZ"
                     /locus_tag="KRM55_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBH1593651.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(42830..43543)
                     /locus_tag="KRM55_001403"
     CDS             complement(42830..43543)
                     /locus_tag="KRM55_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH1593652.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(43547..44461)
                     /gene="murB"
                     /locus_tag="KRM55_001404"
     CDS             complement(43547..44461)
                     /gene="murB"
                     /locus_tag="KRM55_001404"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBH1593653.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(44734..45504)
                     /locus_tag="KRM55_001405"
     CDS             complement(44734..45504)
                     /locus_tag="KRM55_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH1593654.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
BASE COUNT        13218 a         9848 c         6995 g        15544 t
ORIGIN      
        1 ttttataact tttaatttta aaagaggaga atgtatataa gagtattcaa tgtactagaa
       61 aaaatcaaaa gaaatattag aagaaatgga tattgagtaa tcaaagaaaa gattttgata
      121 ttacaaatga tatgtttcaa gaaagcattc ctatcacaac aaaaattatt cttgaagaca
      181 tgccttcaaa tgatgaatta aatcatgttt tttcaaaagg ttgtgaacga aaaatgaaaa
      241 agagaaaaat tgtattaatc acactactat taataggtgt tttgttatta ggaagtatcc
      301 tatataatct ttttttagga aaaacagcta atatttcaat gctaaaggaa tcttggaatt
      361 ttgatatacc aatacctaac aaagaaattg aagtatttga tactcaagat agtattaatg
      421 gagatggaca aagttatttt attcaaggat tttctgaaaa aaatttcaaa aaagttttta
      481 atttaaaagg tggtatagtt gtaagcaaag ataatattaa tgaaatagaa aaatatattg
      541 ataaatttaa aagagattct gttaacatta ataaaagtaa taaaaataaa attgaagaag
      601 attttaaaaa atataagtta gaagttaaaa aagatgataa gtatatatat aagagaaatt
      661 atgagaacta cgtagtttta attataaaaa aagatgaaca aaaattatac agtttaatat
      721 ggaatcagta ggtacatatg tattattaag aattataaat aataaaaata aattttagtc
      781 aatatacaaa aaccttttaa attgtctgga aatcacctct tcatttgtta taaaaacata
      841 caacaaatga agaggtgatt ttatggtttt aaaaaaaata attataagtg gatatgtgct
      901 ttcacatgtt tatcaacatt tgtaatgcct atatttgcta atgaattata aaaatattaa
      961 ataatattca actatagatt atgtaaatta ctctatgaaa aaaatgagtt gtataaaatc
     1021 tggctactgt agattgacta tttcttttaa aattacaatt ataataagtt ttatagaatt
     1081 aaaaataaaa ctttagagat ttttgataac attgtagact aaatttgcca ccgaaatcgc
     1141 tttacagtgg caaatcggtg gcaaatacaa tatattatta gtatataatc tatataaaca
     1201 ttactattgt ttgattatct tagctacagt ttccacatgt gtcgttacta ctatcggaac
     1261 acattttatc aacctcgttg ctgtcatgtg aacacaattc attagtccta tgccgtcctc
     1321 ttgcattttt cctttgtgtt ttaaatttag caccatctac gctattcttc aagcctgttt
     1381 tataaacaaa ggtcaactgt gcagggtcaa catttccgtt ttcatcaagt ccacctacaa
     1441 ttactttttc aacaatgctt tcaaacacat agcggtcaaa tttatcaaga acctcattct
     1501 gttccagagt tttcttaaac tctttcaaac gtttttttat gtctttctca ttatcagaag
     1561 tttcttgtaa cttttgtctt tcttcaacaa gctgttcttg tttacttact aaatcagcat
     1621 atttactttc gtaggtttcc ttatcaataa tttcttccag acgcatatcc acaagtttac
     1681 tttttttctt ctctaatgcg tctatctcct tttccgcttt tgcaagttgt tttgacacca
     1741 cactactact aagagtatcg tccattctct gcaaaaattc ttccagaaca tctttattat
     1801 catcacataa taaacgataa ctttctacaa atgcttcttc aatagctgtt tctggaatac
     1861 ctttgctatg tttacaaaat ttctttcctt tcttcgtagc cgttacacat tgccatataa
     1921 ccttgctgta ttttgagcca ctgtgccaat tacgtcttgt taaagtacca ccacaaaagc
     1981 cacattctag catacagcta aatgcgtatt tcctgctata cttctcacgc ttaccgctgc
     2041 ctaccgttgt tcggttctta tttctccgat taagaatttc ctgtgctttt tcaaaaactt
     2101 cttcactaat aatcggctca tggtgatctt tcatataaaa tttatcttct tcacccatgt
     2161 tttcaaggcg acgtttggaa atcggatcaa cagtaaaagt tttgcctaag agtatatcac
     2221 ccttgtattt ctcattctta ataattccaa taaccgtaga tggtgcccat gtggaactcc
     2281 catacttcgt tttataacct agactttcaa gctcctgtcc aataacagaa ccaccagcac
     2341 catcaacata acggttgaaa atatatctga caatctctgc ttcttcttga tttacagtta
     2401 ttgtcttatc ctctgggtga taatcatatc caatacaacc ttgaaaacct accagctcgc
     2461 cgcgcttcat tttcattttc aacccttttt ttacattggc tgaaatgttc tcgacttcct
     2521 gctgtgcaac agaactaaga acaacaagca ataactctcc atccattgta agtgtattga
     2581 ttttttcatc ttcaaaataa acggcgatat ttctctcttt tagcatacga acatatttca
     2641 atgtgtctaa agtatttctg gcaaatcttg atatggattt tgtaaatacc atgtcaattt
     2701 caccattcat acagtcattt atcatacgct gaaaatcttc tcgttttgtt acttgtgtcc
     2761 ccgtaattgc ttcatcagca taaatgtcag ctaacaccca ttccttgttt ttcttaatca
     2821 tgtcagtata atactgaact tgtgatttat aactgtttaa ctgatcttcg ctatctgtac
     2881 ttacacggca atatgcagct acacgcaaac gctcaatggc ttttccacgg gcttgtcttg
     2941 ccaaaacatt ttttgctttt attacttcaa cttcctgcat agtacacctc cttattttgt
     3001 gttcctttca tattgttatt gtactacttt aaaaaacaca attcaagcag ttatgtcaga
     3061 aagcacctta tagtctttca tcagcctttg ttttacaaga gtgtattctt tttcagaaat
     3121 cagtttacgg gcaagcagtt gttttaacat agcaatttgc atactatacc taattatatt
     3181 attcattaaa accctccttg cttttttatt tatggaagta atcagacggc ttcggcagct
     3241 ccactggact ttcaccattc ccattctgat gggtgaaccg tgtcatacgg gtgtatcatt
     3301 attcagatat acgagtcatg gcagcaacct ttccaaagat cgcttgcggt tcactggcat
     3361 aatcgctcgc tgctttcccc atttcagtgg tcgtggcgtt ccagtccgct ggctcgtcgt
     3421 atatcaaacg tatctgatta ctgtattcac ttgtcaaaga acggaaaaga gttaaaatga
     3481 ggtggtagat actctctgtt atatttactt cactttgact tcaaacccta agattacttt
     3541 aatcaacgct gcccgtatcc tgcctttcag ttccatatca agcacgatat acatattccc
     3601 gtgttcgtca tagaacgggc gtaggctggc ttttgatatg taagcgtcat aatggttcaa
     3661 aatcttttca attgccacct cgttaccgtc agctgcagaa ctgatggtcg agaatgatgg
     3721 acactttttt gtagacttca tcatgttttt attcctcctc gtacatatcc ttaataagct
     3781 ttaatgtgtg cagcctgttt ctacatacgg aaaatcgttc catttccata acctctgcaa
     3841 tttcagcgtc ggtcatttca agaaagtagg acataagcag aatgttacgt cggctttctg
     3901 ttaattcttt gatagcttca cataagcgtt catcatagat atggacttct gaaccaaata
     3961 catcaaatga cgtaaactca acgcaatatt cgtccatggc accgatctgg tttaactcca
     4021 tttcagataa atcacagaac ggcgtttcac gtcttgcacg tctgccaagc tctcggtcat
     4081 agttctttac agttcgtcct acaaccttgc gagctagaca atcaaattga agtctgatag
     4141 cgccctcgaa agaagatggt ttcataatct cacccccttt ccagcgaaag ttgctaaagc
     4201 gaaaagactt ctacctcttt tcgcactaac actcaccatg aaaggtggga tttgataccc
     4261 aaccgcaaaa attttttgaa aaagttttat gcagtaaaaa agcacaaggg caatacagac
     4321 gtactgatct tgtgctaaac aaattattcc tgttatatgc tgtaaaaaac cacatatagg
     4381 agcattatgt tccgtagaat ttaaatgttt ttttaatgaa ctaccgatgg tcgaaagttg
     4441 ttgaatatgt aagtgtttca tacggctacc cctagagccg ataaaacaag accatccagt
     4501 aatttgtcca acgttaggca aaaataaaac ggcggctata taaccgtcgt cttattcaaa
     4561 agttcaaaaa gaactaaact aaaccctcta aagcagtatg tatttataat cagtcttgca
     4621 aaataacaaa gtagaattga aatataaggt agcaatcctt gtgcatctaa taaacttata
     4681 ggggttacag cagaccacgg aataatattt tgtatacttt cagatcaata tagtccaaca
     4741 aaaccaattc ccgatattta gtaactaaaa agtaaactag agtagaaaac atttctttgc
     4801 aaaacacaaa taataagtaa tggactcatt gacaatagat tgagaaatcc agttttttag
     4861 acttagatag attatctcac ttgtaaatga tttaagttct ttgacttcat atatagcggt
     4921 ataatctgtc aacgtgatca ttacaaacca taatgcctat ataacatact ttctaagcaa
     4981 aaactttatt ctattagttg gggaatacaa aatatttatc attgtgcgtt caacatattc
     5041 tttttgtata aaaatgtaat tacaaaacac cactcaatat aagatagata ataatttgaa
     5101 taggaattat caatctacgt aaccattcat tacctgtcat tgttgttaca atagatttgg
     5161 gattctgttt ccattacata atttttttat ccttctttca gatatctcct cattttatcg
     5221 aagcttcttc tacagacata cattccataa taaaatctac ctttgaatat tatttcacga
     5281 tttcgttata gacgcgtaaa caaacaataa aaaacgaaat ttcttttaag taccataatt
     5341 tttatatcga aattacaatt atccacttat atacagcatt tataggtaat tcaatgataa
     5401 aaaaacacat actttactac taaattgcca caattgaatg cgccttgata tgatagggag
     5461 attccacaat aaaaaactgt gcatctccct tgattcattc atactgatat cttatttata
     5521 agactctttt gtgtcttttt ttggtttcat ggaccaaaat actacattca ttacaataac
     5581 aatcagcaac acaactgcca tagccaccca aaagccgata ttaagaccaa gccattcggt
     5641 agttccaaaa agggtcatcc aaagttcttt ccagttcatc attccacctc cttaaagcag
     5701 ttctccgaaa tgacggacat aggctttttt taaacttgtt gccaaagtca tatacagcag
     5761 aatacatgga atcagataag caaagtatgc tgcaggcaat gcaacaaatc caagcatagt
     5821 tccaaacaca gtaaacggaa taatggtcag aactataatt ccagtcattg ttagcaaagt
     5881 caccggagct gatgcacgac tctgaacaaa aggtagcttt ggagtacgaa tcatgtgaat
     5941 gactaatgtc tggctccaca tagattccac gaaccaccct gcttggaaca tcccgatata
     6001 ctgtgcctga agcattgcca gttctgcacc gctgaaatga gcaggcaaat cattaaataa
     6061 tacaccattc gatacgaaca atggacaaaa tacaaagtac ataaaaatat aggttgtaaa
     6121 atcaaagata gaactggttg gtccaatcca gatcataaaa cttccaacac tggaagcgtc
     6181 ccatttacga ggtttggtaa taaactcctc atccacatta tcccaaggaa ttgcagtaca
     6241 ggataaatca taaattaagt ttagaaatat aagatgaaca ctcatcattg gtaagaaagg
     6301 tagcaaagca gatgcagcaa gcactgagaa catattgccg aagttggatg aagcagtcat
     6361 tttaatgtac ttgatcatgt tggcatatgt ctttcgtccc tcaataatac cctgttccaa
     6421 aaccatcaga tctttttcca atagaataat gtcagcagat tcttttgcca cgtccacggc
     6481 ggtatccacc gaaataccaa tatcggcggc tttcatagct gcagcatcat taataccgtc
     6541 acccatgaaa ccgaccgtat gaccattttc acggagaaca gaaaccacac gggctttctg
     6601 atcaggggtt agctttgcaa atacatctgt agactctgcc actcttgcaa gctctgcatc
     6661 gcccatttgt tccaaatcag aaccgagaag catattgcga acctctaatc ccacctgctt
     6721 gcagatagtt cgagtcactt tgtcgttgtc acctgtcaaa attttggtta taacaccatg
     6781 gtctttcaga gctttaatag catccgcagt agattctttt ggaggatcaa ggaatgccag
     6841 atatccaatc agtaccatat cacactcatc tttaacacca aatgcgccga ttggggaagg
     6901 attactcttc tgtgcaatag ctagtacgcg gaatccctta tcgttaagat tgtccactgt
     6961 ctccagaatt ctgtaacgaa cgtcatcagt cagaggctgc actcctccat tacactctgc
     7021 aaacgcacaa atagagagca tttcttccac agcacctttt gttaccatct gggtcttacc
     7081 cttattatcc tgtaccactg tagtcagacg acgacgtgtg aagtcaaaag gaatctcatc
     7141 tactttcaca tagttttcag acaggtcaat gagacgcgaa tctgcggctt cctcttcctc
     7201 cgtcttatgg ataattgcca aatccatcag gtttttatag ccagtctgga agtaactatt
     7261 gaggtaagcg tgacgcagta ctcgcgtatc gtcctcgcca tttacattca gatggtattc
     7321 cagcacaacc ttatcctggg tcagcgtgcc agtcttgtca gtacagagaa tatcaatagc
     7381 accgaagttc tgaatggaat tgaggttttt aacgattgtc tgcttcttgc tcatggaaac
     7441 agcgcctttc gcaagacagg ttgttacaat catcggcaac atttctggtg tcaaaccaac
     7501 agcaatagaa acgccgaata agaaggccgc caaccaatcg cccttggtga taccattgac
     7561 aaagaacacc agcggaacca taatgagcat aaaacgaatc aatacccaag aaacggcatt
     7621 gacacccttg gtaaagcttg tttcaaccgc ttctccagca actgcggacg ccatagagcc
     7681 aaacagagta tgatcgccaa cacaaacaac aacagctgtt gcgctaccag aaattacatt
     7741 actccccata aaagcaatgt ttgtgtaatc agtcacgctt tctttctgag cacttacatt
     7801 gggtgttttt tcaataggtt cactctcacc agtaagactt gcctgactga caaacaaatc
     7861 cttcgcatcc aaaatacgaa catccgccgg aatcatatct ccagcagaaa gatgcacaat
     7921 atctcccacc accaaatcat ccataggaag ttcttttttt tcatagtttc tacgagtaac
     7981 tgtacaagtg gtcgtaatca tggctaacaa tttctctgct gcatttccgc ttctggattc
     8041 ctgtacaaaa cgaagcgtac cggaaatgaa taccattgtt aaaatgatta caacagtcag
     8101 ggaatcaaag tcctctggca cactgccaaa cagagaaaaa tacggaaaaa tcatatctgt
     8161 aattgtggat actaaagcca gacaaaataa aatggcggta aatggattga taaatgcgcc
     8221 aaccagtcgt tttgccagag atttcttttt ttcatgagtg actttattgg taccatattt
     8281 agcacgactt acggatactt catctacttc taagccacga agtgtggtat gaagtttttt
     8341 taaaacttct ttaataggat tggttgccgc aaattgaatg cggcggttct gttcgtcacg
     8401 gatgactgct ttttctacag tctgacgaat agccatacga ttttcttttt tgttcattgg
     8461 tcttacctcc ttgaattttc ataggggcaa ggaatattat atgagcgaca cggaatctcc
     8521 aaattctcat ataatattct ctgccttcgt ggactgacat cagagtccat gtctttcacc
     8581 tcacaatctt aaaaaaatat ctatgtgaaa cctcaatgtg gattattggt tgcgatagcg
     8641 gacacttttt tcgatatacc agacatcaaa gccggcaaca atcagccatg cgattattgc
     8701 aaatacaaac cagtggtttg aaaatcccgg caaaaatcct ttcattaaga atataatccc
     8761 atttaacgca atcatttctc caacattacg acaaagcggg acaatattaa ttttatcttt
     8821 ctcctcctgc ggcatatttt tccacaggga aagatgacga tatccttttc caaaggccaa
     8881 ccaaaagcct gcaagagtaa ataaaattcc aaaaaagata catgtaaaat ccatcgtttg
     8941 ttcctccttt caatgcttaa acctgtttct tagttttgtc agcttcagaa gtttaatgaa
     9001 gagcacaata atagtaacag caagaataaa ccagatcaca atactcacct gataccatat
     9061 cttaaagatt accattcttt gttcaaagaa attccaaccc aaatagctac ataagattgt
     9121 aaatacaggg tagaaagcaa aaagaattgc tcgtttcaaa tcttcgattt ctctcctcac
     9181 tcacaacacc tcccaaccag cactaatcac ttccggaatt accaatacct gcccaacgat
     9241 tccttctaaa atattgtttt tggattttcc gacagaacag tattctgcga caatctcaac
     9301 cttgtcacca accacatcac cgctttccag attgttcaaa aagagcgtct tacaggaatt
     9361 gctgttaatc agcaataagc gtatatcctg ctctgccttt tcctgacatg taaccgaaat
     9421 acgatactgc ttttcagatt catcactgga agtaattggg tgaaactttc ttgcaaaggg
     9481 acgtagaatc aggttggaac caattaaaat agtagcggcg gtgatcgcca ttgcatacat
     9541 tcccgtactt gcaagaattc caatcgctgc agtacaccat aaggtggcag cggtattcat
     9601 tccacgtact gtccctctgt ccttgaaaat aacaccactg cataaaaaac caacaccgga
     9661 tataatactg cttccgacac ggaatacctg atccgaaccg tagagcatag gaaacaaggt
     9721 aaagaaactt gtacccatgc agattaacac attgatacga atacctgcag gatgaccagt
     9781 caattgccgt tctaatccaa taagaaatcc aagtgttaag gagagggcaa ttctcaaaat
     9841 aaaatctgtg taaaacatat gaaacacctc cctttaacta ctaacagtat ataaaaaatc
     9901 caaatacaat cctatggcta aagtcttgcg attttcttgc gatttggtaa gaaaatagac
     9961 ggactgaaac cgaaaatggt cttagtccgt ctttgtcata tctgatcatt aaatttgtat
    10021 ccaatacccc agatggtcaa aatatatgtg ggacaatccg gagcaggttc aatctttttt
    10081 cgcaacttcc ggataaaagc cataatgttg ctgttatcca gaatataatc ttcctcccat
    10141 acggcacgat aaatctgttc ctttgtaaaa acttcacctt tgttctggac aagaaagtac
    10201 aaaatatcaa attcctttgg agtcaggttg acttcagaac cttttatcag tacttttctg
    10261 cctcttggat aaatttccag atcccctgcc aggattctat ctgacagagt acccactggc
    10321 caatcgcttt cttctgatgc tcctaacaat aacgaagata cctctccacg aatcatctcc
    10381 tgaataccag aaagtaaatc cttcgcacaa tcactgtccg gtggatctct tagtagtttt
    10441 tctaatagcc agatttcaag agccgaatcc atcggaatat aactaatatt ctttttcatc
    10501 atgaatgcct cctcttaaat caactcttga tattttttct tataaaaata tttggctact
    10561 gaattcagca gcatatagag agataccacc agcagtaaaa atacgaaata ccaaagaggt
    10621 aatttcgtca gtccaaacaa cgacgcaccg ccgacaaatg taagggaagt aaaagcaata
    10681 atccccacta gagttataga aatgaccggt gcagatgccc tgctctggaa aaaaggaatc
    10741 ttggaagttc gcagaaaatg taaaatcaaa acctgtgtcc acatagattc caaaaaccat
    10801 ccagtctgaa acagtgctac atactgaagt tgcagggaag gatctgtaag ctgcagatag
    10861 gttgcccctc cacatagcat cggacatagg aaataataca aaaataggaa ggtgacaata
    10921 tcaaacagag aactgatcgg tccgaaagac agcataaact gtctcagtgt tttgccggac
    10981 cagtctcttg gggacagcat ctcttcctca tctacattgt cccaaggaag cacaatacac
    11041 aacgtatcat acagcagatt caaaagcaga atctgaattg aagtcatagg caggaacggt
    11101 aaaaaggcac tggcacaaat gatggaaaaa atatttccaa agttagagct agcggtgatt
    11161 ttaatatatt tcagcatatt ggtaaaagtt tttcgcccct ccattacacc ttgctccaaa
    11221 acattcaagt ccttttgcag caaaaccaca tcggcagcat cttttgctgc gtccactgcc
    11281 gtatctacag agattcccac atttgcttca ttcagtgccg gaatgtcgtt gactccatca
    11341 ccaagaaatc ccacggaatg accattatcc tgcatagcag agacaagacg caccttatgt
    11401 cccggagtaa gctctgcaaa aacatgagta tgttccacag cctttttaag ttcacagtct
    11461 gtcatttcat ccagttgagt accagttaag atacgctctg tataaatacc cacccggcgg
    11521 caaacagaca cagcaatcgc tgcctggtcc cctgtcagaa tcttagggat aacttttaat
    11581 cttttgagtg cagttacaga ctcctttgct gtctgctttg gtgcatcaaa gaaggataga
    11641 tagccaacta gagtcatgcc ccattcgtca tcaggagtta ttttcttttg cgctcccaca
    11701 ttttttcgtg ccaccgcaat gaccttcatt ccgtcctgta acatttcacc tactacagaa
    11761 gatacactct gtctcgcatc ctgccccatg gggagaagtt ttccacgata ttctacatgg
    11821 ttgcagcgtg agaatatatg ttcaatatca cctttcataa taagctgact attcccattg
    11881 ctatcctgta caagtgtact gacaaactta cgagcatagt caaagggaat ttcatcagct
    11941 ttttggaatt ttgtcagaag atttgcgtaa tgggcttccc gccctggcat ggtattgcag
    12001 gcaagaatgg cattatcaat ggtattgcag acaccagaat gatagcagct attcagataa
    12061 gcaagatcaa gaacctctgc attttcattt ccaaaaatat ccatataata ttccagcagg
    12121 atgctttcat tggtaagtgt tcctgtttta tccatacaaa gcacatccat gctaccaaag
    12181 ctctgcatgg cattaatatc cttgataatg gtctgctttt tgctcatagc aagacttcct
    12241 ttggcaaggc aggctgtaat aaccatagga agcatttccg gcatcagacc tacagcaact
    12301 gacagggcga aagcaaaaga ttccatccat tttccatcag taatccccag taatataaat
    12361 acaatgggaa ctaatatcgc cataaaacgt atcatcaccc aggcgatgga atcggctcct
    12421 tttttaaagg aatttttatc atcagaatcc ggtttggtaa atcctccata cagggtatct
    12481 ttgcctactg ccagtacaat gccttcccct tttccactga tgactgtggt tgccataaaa
    12541 gcgaggtttt caagctgagt cagtgtatcc tgctctccgt aactgagttt tcggcagctc
    12601 ttttcaatga tggcgctctc gccagtaatc gcagcctgag agataaagag atccgtaatc
    12661 ttcgtcaatc tgatatccgc cggaacacga tcacctgcag agaatagtac aatatcccct
    12721 accactaatt cttcgccagg aatctctatt aactttccat cacgcctcac tgtgacgctt
    12781 tcatgaacta ggcgatcaag ctgagcagca gcgctctttg ctcgcagctc ctgaatcaga
    12841 cgaattacgc cactaattac gatcatggaa aagatgataa tggcggtagt agcatttctc
    12901 gcaaaattgg atgctacgaa aacatccgta acaagagaaa caatgcccag aacaaaaaga
    12961 atcacatgaa acgggttaat aaatgcccgt ctcaaccgtt gcatcgtcgt atcatttttc
    13021 cgcccattga agctgttcgc tccgtatttc tcccgcattg aaccgatttg ctcaatggat
    13081 aaaccatccg gagatgagcc aatgtctcga taaatttctg atgttctaca gtatgcgtat
    13141 tttttgatac gactatcaaa tagtgttgct tttgacacga aacatcccct cctttataag
    13201 tataagtaat aacattttaa cacagtgttc tgaaaatgct atatttatat tcttgctttt
    13261 ttcttgcaat ttactttgat atggcatttt tcagctcgat caaatccgtc tcgttagggc
    13321 gagataaatc cttatcaaag ttttcaacca ttccttctaa atttggagca cagatggata
    13381 cggcaagcat tttctcatag cgctctcgca cataaatagg catttcccct tgacacatat
    13441 gagtgctgac aaacttcttc ttggttttca ccttgaccat gtatcaaatt taaatgaact
    13501 acttagaaaa gttgctcata ataatatttg tattatgagt gatagaatga caaaagtggc
    13561 agtatggaaa ccgagtgtaa aaacaataca attagtttgt atggaatatc tgaactacat
    13621 aattgaccac tctgtaattt atgaaaaaat acaatgcgca aattggaacg ggacagaaga
    13681 aaccaatagt atttttaata attccccttc accattgatt actcttatct attcttgcga
    13741 tttacaacaa aataaaacaa cataaatttt aaatacgttg actggcataa ttcatatgta
    13801 tagtaagtct acaattaaga tgcgcttttt ctaatccaaa tatattaaga aaaaaatttt
    13861 gcgaagccat taatactttg tttaagatgt ctttcataaa tataaagaat aatgctctta
    13921 acaaaagcgt gcaaattcct aaagaaatgc acgctttcaa taattatcct ataatcttcc
    13981 aattgctctc cttatgtagc actaattcaa actgcgatac ctgtgttgcc tttgtctgat
    14041 tatcaatgaa tttcacggca accttgactt tcacattgtc cccatcaacc gtaaagatag
    14101 ggtttaccaa ttcagaatag aggtagtccc tgccgataga ctcaagcaca tttccagaca
    14161 catagtaagc aagctccttt tctgtggctg ttgggtatag cttaaagaaa gtttccagaa
    14221 atgcagtagc gtcatttatg gtatccgcgt ctacacttgc gtctgcttct ggtgtctttg
    14281 gttcatagtc tgatttctcg attgctggtg caagggtagg gttctgaata attaccatat
    14341 tcccgccagc gtccacatga acttttacgg tataggttgc cttaaccgct gttgtctgtt
    14401 ccccctcttt tatctgctga tctacttcgt aggtagcgga aaaagtgtcc gttccagact
    14461 gttcaatgct ccatacaatc acatctgtaa tggcagagct ggtcggtata tccgttctaa
    14521 tggtatccat attcaagtcc tgcaattcct ttgtcagata accgctgatt gcctgcgtcc
    14581 ttgcgtcaat cgcttctttg ctgttactcc atgtgtaata ggactttgca aaattcttca
    14641 cgaaattttc tatcccgttg gtgtcctgca agcgaagctc aatcacttct ttttcatggg
    14701 tcgtgtgctg gtcaatagcg gtaaaattct tatatactcc aaagctcacg cttgcaataa
    14761 gcaccaccca caatgcaatc acggttttct tatgtgtgcc taccttgaca gtacgtacct
    14821 ttttttcttt gacattttct gtctgtttct tattcttctt aaacatattt ttcaagtcct
    14881 ttctattgtt ttactcgtcc tgcaccgatt aagtgctgtt gccagtaact actacttagg
    14941 tctgtatatc ctatcgggtc gcctgcatgg tacatctgat tatttcccac atagataccg
    15001 acgtgggtta catacgaacc agcgttatag gtggaatgga aaaataccaa atcgccagcc
    15061 tttgcctgcg agagtggaag atgttgggta gcgtcatact gggcttgtgc cgttctcggt
    15121 aaggagatac cagcttttcc atagcaccat tgcgtcagtc ccgaacagtc aaaggaagtg
    15181 gttggagaag aaccaccaaa cacatatttc cacccttgat atttcaacgc ttcattcatt
    15241 accttttgtg ccagctctcc cgatacctgc ggaacagtta aatactgatt gactaattcc
    15301 acatagaaca tatttccata gccataccgc cagcctccgt tcttcgcaac ggctatcggg
    15361 ttggtatagg ttactttttt tccacccgat ttctcacggg cgaagctctc tgcaagatta
    15421 aaagtgtgtt tctttccgtt tcctgccaca tagcccacat agccaccgcc atagttatag
    15481 gactgtatcg ctacattcaa atcgtcgata tcttgatttt tgcaggaaga aagcagggac
    15541 gcaaaatact tacacccctg cttgattgag ctttccgtat ctaaggaact aggcggtaaa
    15601 ccaagacttt ctgaactctg cataacatct tctgccgtac cgccactttc tacttgaatg
    15661 atagccagta gtacattgac gtactcggag ataccgtttt ctctggcgta tttttctacc
    15721 ataggctgat gtttcaaaac ttctgcggat aagttcatac ccgtaatgcc agaagaaaag
    15781 ttgctgtttt cgtcgtcgct gtccgcacta atcagcaccc caaagaaaag caccagagaa
    15841 aagagaatag gaaacagact tccaatgata gcgatatgtt tcagtttcat tttttcttct
    15901 gtcctttctt cgttacaaga ttacggattt tctctgtggt ctgctggttc ttctggacag
    15961 tctgggtctg ctgaaccttt gtcctacggt ctttggtgta attctggcgt gtttcctttg
    16021 acacggtaac tttttctaca ttctgcctat atgtcgattg ggtcgctttc ccgtcaggag
    16081 tactagaaga tagcggacgt tctttgacac cgcttgtctt aactggttcg cttgctttcg
    16141 tagtcggagt tgtggcaggg cgtttgactt cctgcatttt ttccgcaccc gtctttgaaa
    16201 cggttgaagc tgtggctggt cgctcatggg gacgggtagc tcccgttgtc gctgatccgt
    16261 cagcctttcg ctgtgcctgc cttgcttctt gtgccttttg aagctccata cgcttgacag
    16321 cgatactttt cttatgctgt tcctgctttt ccaagcgtcc cgtctgtctg gactgctgtt
    16381 cctgcaccat accacgcttg aaatcagaca cgctggactt tgccttttcc tttgcggaat
    16441 acaccgcata agcggtctgt gtgggcatat ccttgatatt ctctttgaca gcgtttgcct
    16501 tgtctttcac tttatttttc gtatctaaga cagcacccac ctttgagcct gcacgctgtc
    16561 ccatactgga agtggtattg ccccgatttt ctttagaagc cgtatttttt ctttcggctc
    16621 tcttgccagc aacggcactt ccagctaccg caccagccac accacccgaa ataccgccag
    16681 cacttacagc ccttgcaata cggtgttcca tacgcctagc ccgatgtcgc atgaacagat
    16741 acggtctgcg gaatatcctg cgtcccatgc tttgactgtc gccagcgttg agagaaaaca
    16801 tactcattaa gtcgcccagc ttcatataga taccagcgaa acatactatc tgcaagaacg
    16861 ccaccatgaa aaacggatag tccgtggata tgttataaaa catactggaa atgctaaacg
    16921 caaccgttac aatgagcgtt attcctgccc gtgtcattat ggtattaaat accctcacga
    16981 ttgcctgctt tgccatgctt tcatagctcg gtatcatgga aagtagaaag ctgataggta
    17041 aaaacatagc gaagataata aaaagtatct ggctgaacaa catcataccc gtaagcaaga
    17101 atacaaatat cgtaatacca agattaaaga acaagaggaa gaacaccata cctaaacggt
    17161 ttaccacctg cggtatcgtc agattgttgt tgtcgttgtc ctcgatttct gttttcacga
    17221 cttcttctct ggtctttccg tcctcgtcct ctggacttgc cgatacgaga gcttcgacac
    17281 ggtctgtccc gatttcctct gcgttgctgt ttccaaactg taagagtagc cacggctgtt
    17341 gtacttgaat agaaaatagg ctgtcccgta tcaagtctac gctgtccttg ccctcgctgt
    17401 cagagttggg gagcatgatt tttgttccca aatcaagcga agcggtactg atgtctgatg
    17461 aaaattcatt tatcttcttg atgtagtcgg gagcgtaggc aataaacgaa gcggacagca
    17521 cgaacaccac cacaaagttg ataacagcgt gaagtgcctt gctggtttcc cgttttatca
    17581 gtcccgtata ggcaacatac attcccacca ctaagataat aagaagcagg aaaccaacat
    17641 agaagcccgt agaagaaaag ccgttctcgg taacgcctgc aagggtctgt atgctttttc
    17701 cgatactgtc tgccatatcg ttaataaaat caagtttata ggcttcctgc accacatagc
    17761 cagttgcatt gcttaaataa aggcttatcg tccagacaaa gttggtaatg cagtaaagcc
    17821 cgtactgtac cgattttccg ataccgtcca gccagttcca cggaagccac gaccagctat
    17881 tatcgacgaa aaaatcaagc tggtagttgg aaagcggata ttttgaatat agattttctg
    17941 cgtttatggt atcgtccaca agccccgtcg catgagccac cgtccccaga agtgaaagca
    18001 ggataaggga aagtgccacc acgaacagag ccattttgag aaagtgaagt atcttccttt
    18061 ttgtgaacgc actctgtatc ctttctttca tcactccacc tcatttctct gtacgggcgg
    18121 tctagtatca aaggcgtgta gtaattcttc aaagactggg tgtatctgca ccacaccgac
    18181 acgcccgtat aagtcctgca ataaacattg tccgttctcc aaatcacgca agcgtttctg
    18241 gttgttttcg tcgtccttgt cgataccgaa aaattctaag gtctgcttta tctcgttgat
    18301 gtcagtagaa cgaaatgcaa acttcaaacc gatattgttt ttcagacttt cctttgacac
    18361 gtcatagaca gactgggtaa cgaaataaac gcctgcctgc atagctcgtc cagcacgaac
    18421 cagcttattt gatagggttt cgccttgtgc cacatttaag aacgcccacg cttcgtccaa
    18481 atctacaatc ttaaaaatgc ttctgtccga atggataaaa tcaagggcaa aggtactaat
    18541 cacaatcagc atagacaccg acaataattc aatggtcgtg tattcctcaa aagtggtatc
    18601 tttatctggc agtacaaggt ctgctacttg aatgatattg agctggttat caaggcttat
    18661 agcattttct accgtcccgt ctgaaaacag caggtgtgca aagtcgtagt ccgtgaagct
    18721 gtcgatatgg tctgcgatat tgcgtgagat agcggtatct tcttttctca attcctcaat
    18781 aacgtgtaac agtcctctat tttcactctg ggtaacagaa cgcaccgctt ttcgtaacac
    18841 ggggaatttt tcgccgtccc tagaggaaat acccgtaagg aatgttaaga tgtcgattgc
    18901 cagactttca gcgtctttca cattcttcat aatcacaaat gggtcaagaa gtcctgcatt
    18961 gtccttgtcg ctggtaaggt ttacgatatt gatttcatgg gctatctctg ggagcgtttc
    19021 tttccagttg ccacgctcac ttttagggtc taacagaagt gcttgaccgc caaacagcac
    19081 cgcataatat acaagtagat tgttgcagaa tgactttcca ccgccaagac ttcccacaaa
    19141 agcagaagca agggcattag taactgtgcc ttttactccc tgcgaagcta aagacggttg
    19201 caggtacaca tttcttcccg tatcaacgga atagcccata tagatacccg tgttttcccc
    19261 taactgctgg gtcgcaccaa aaccaagccc agccaagaag tctgacttta catactgcac
    19321 atagtcattg atatatcgct tgctggcagg taaaaattca gaatgaagtc ccaacatatc
    19381 gccaacagga cgcaccagtt ttacattgag gtcgtcgtaa aagtccttga cttcatcaca
    19441 acggcgtttc agctcgtcaa gatcgggtgc agacacccgt atgacgtagc ttaacttata
    19501 catactttct ttgctctggt ctaaatcggt ttccagctcg tccacgctgt ctaaagcgtc
    19561 caccacattt gagctggttt cacttcctgc ttgataggcg tgattatcca aatctttcaa
    19621 ttcctttttc ttgttgcgga ctgtcgttaa tgccttacgg ttctccacga tttctacatt
    19681 catagaagta tcaacgggga atgtgaattg ctgttgctgg aaatagaaga tttcagagga
    19741 cggaaaatcc aactccccga caattacatt gacggtaaaa taggacacat agctttcctt
    19801 gtcctcatgt tccaatcgta aataccgctg gctttcctca atcacacacc ttgtcggacg
    19861 gataaggtcg tagtatttta tcagcgtttc tttcttcaat ttcttctttg gtagctggta
    19921 ctcataatct tcataggcga taccgtccct gccgtaaaga tgttccatga gatacccaaa
    19981 atcatggatt tccaagcgac gcaccttaaa gcgacgggag attttatttt ccagtaactt
    20041 ttccattttc atgtaacggt tgatttcatc attcggcatg gaaacaaaat cattcatcag
    20101 cgtgtggttc acttcatgaa gaaattcctt gaacgtcagc catgccgatt ttttgatgtt
    20161 cttcagattg agctgttctt ccgtaaccat gagcttaaag ccaagaaaaa agcggtagtc
    20221 cacttgattg tccccaatca ttgatactaa cgcttcggtc tgttcgtcta ttttttggac
    20281 tgccacctca cgaagtttgc ctgttaccag tttctttgac tgctcctgca tacttctaat
    20341 ggagctttct gtggcaatct gcaacgcatg aatttttccc tcacgggact gtgcgattag
    20401 ctgtcgaaaa ctgtcatgca cgataaattt ctgctctgcg gatagaaaag aatagttgta
    20461 cggtatcatc tcatagtagg cgaacacctc attgtccttg ttccagacaa ggttattgtc
    20521 aatatatttt atcaggaaca tagttcacac tccttactgc cgtgattgtt tcattcaata
    20581 tctgcttatg cagttttacg gcttttcctg cataagtgat tttaggtcgc aaggcatagg
    20641 ttatctgtga tttcaaaaag ctgtacggct tctttccgtc aaaggttttc tgcgacataa
    20701 accaagtgag agcaacggga ataccgaagt atttgagaaa tgctccctca atcatggaaa
    20761 gtgggggcat atccccaaac agaatgatga taaattccgt aatcacaaac catgtaatct
    20821 gtgtaaaggt aacgggaaag ggtaagttaa agtcattgat tgcatataag actttttcca
    20881 cgttccagat acccgtgtag cttttaatct ttttcaagtt ctttcagccc ctttcgtaag
    20941 ttcttcaaag agaaaaggac agccattttc agactgtccc ttaaagagaa atacgctgtc
    21001 agtagcaaca atgcttgttg ctgatcttcc agcgttaata tggtatctca cagatacctc
    21061 ggcttgtttc aatgaatcga ccacccatat ccaaatctcg cccgtaggct tcatagtcaa
    21121 tatagttctg taagttagct ggaatgtccc caagtgcgtt caattcgtct atgtagtagt
    21181 aggcaacatc tgtcatggtt tcacaatcgg gataaaaata aatatcgtcc ttatgttcca
    21241 cgacttcttc cagcgtccca tagtggctga taaattcgtc cagacactct acgatatagt
    21301 cgggaagttc ctctatcatt tcatacattt cattgagttc ttcaatggaa acatattccc
    21361 ctatgtcgat aggaaagttg tcggtatcat ggacagcgta ttcttcgtac tgttcattca
    21421 agccgatttt ttcttttaca tcttcctcgt caatagggaa agtgaaccac gcaccgacta
    21481 aatatccctc attgtatctg ccaagattag caatataaac cgccatatca tcaatcataa
    21541 gcaccacctc atttcctatt ctggcagttc aaagatactg ttttccgtta caagatagcg
    21601 tttgttttca agtaagtgag aagcgtaggc ttcaaaatcg aaatagtatg cttgacagtc
    21661 ctcggataaa tgtttgaatg tcgggtcgtt catcagcttt tgccttgcaa catctatcat
    21721 gcttttacag tcgtgataaa cggtaatcac gttcctgcaa atataaagtg cttctaagtt
    21781 ctcaaacacg gtaagaagtt ctacatattc ttcctgcata tcggctgata gctggcggta
    21841 cataaaatct aattcgttaa gctggtacac gctggtgtgt tcgtggactt catcagcata
    21901 aggcaacacc ttttcgataa tgcggtaatc ttgactttct gcaccgacac ctaacttttc
    21961 ttcaaactct gcaacatcta tcggtaagtc aaaccagtat gatgttgttt cttcgccatt
    22021 tgttcttccc gtttccacca gtacccttgt ttcctgcatt gttcctcacg tcctttctgt
    22081 tgtttcatca catcttttaa ggtctggtat gacataccaa acacatattt agaaaaatct
    22141 tccaactgtt tttcttcata gtcggcaggg ttcagccgtt tcatttcatg ccacacctta
    22201 cgcttgtaag agggcaggtc ggaaatgtat tcacagccga cttttgcctg catatcttta
    22261 aaaatatcgt tcatttcatc actccaatct gaaatttagg taagaaaaaa gcagtcaatc
    22321 ctaagactaa ctgctttgtg tgtaagtatg aatttgttta agtgtaactg atttaccatg
    22381 tgtactcgta aagtttactg tatgtttgac ttttaaataa atatatacaa tcaatcattt
    22441 gtaacttgcc gtcttgttca aatttactta ttatcagatt atcttcatag atatatgcta
    22501 agaaagtatc atactctgca tagtattttt ctctaaaaaa atttgactct ctaaaatctt
    22561 tttctaaagc aattcttata ctgtctaaag catatttaaa gttataacaa gtattaaaac
    22621 taaacttgta tggaaaaaag aaaaataagt ttttcttgaa agtaagcaat ttcacatagg
    22681 tttgtatatc aaattcaatc gttccatact catatttctc tgtaagacaa gaatgtaaac
    22741 tttcacaatc ataatcccgc aacgaagcaa ataacctagt tacagtcatt tgtgtatttg
    22801 gtcttctcgg tggacactta ccaattacac catcacagaa tttctgtatt tgaccagtaa
    22861 gttcttttga agcatgaagt cttgttgtgc tttcaagtaa tttaaagtcc atttgataat
    22921 taggtgagtt acaatcacat tctccatgat tttcagattt aggtggtaca tattctgcaa
    22981 aatttgattt ttctctaaaa tatattgatt tattaactaa ttccaacaag tatttttcat
    23041 aattacaatt ttcttcatct ttaataaaat ttttgtttat gaatactgca tgtaaaatat
    23101 ccactctcat ttcatctgaa atcataagca cttttattcc tttcaaaaaa taatttatcg
    23161 tacccacatt ataacattct catattacag caacaataaa attcgttatg ctccaataat
    23221 cttattgaac agctctaaca gtacatcttt cacaccgcca gcgttgaata ctaagccgac
    23281 agcaataagg gcaactacca agaagccaat aagttttgaa aactcacgct tgaaccctaa
    23341 gtagataccg ataaccacaa tcgccataag cactaagctc tgtgcatttg ataaaaacca
    23401 ttgatacaaa ttttgtccga aattcattta attgtcctcg ctttcttcta attgtttcat
    23461 ttcatagtca gcttctttgc cgatactcaa aatacacatc aagactacgc cgatacccat
    23521 tcccatagat accagcagga agtcttttac taattcccac attttttatc actcctaact
    23581 ttccaccaaa tcttttgcag gggtcgtctg ctgtttgatt atcatttcat gcttttcact
    23641 caagattgcc tgcttttcaa tcgtttccat gtagtctgta ccgtttccct tatcaatctt
    23701 tttcagcatt ttcaaggtcg gtgctacctg tctttgtacc caacgcaatg tgcggtctaa
    23761 ggtgtaaggt tctggttttg tcgtcagttt cagactttgc cgattatcgc caataaacca
    23821 agcccagcgg tcattgagtt tccagtcatt tttccgcttg tctggttctt catcaataaa
    23881 ccgcacatac tggttgatga tagaaaaagc ggtctgctct gcgtcatagt aggtcagcaa
    23941 atctcgtact gcatagtaag cacgttcatt tctaagccgt atctcaaaac ggttgataat
    24001 gtcggcttct tccagaggtg tacctaattt gacatactgc tcatagtcct tttcatagat
    24061 acagaaatac acatctgatt tcagcgaacc aagataaagg gtactcccca tatattctct
    24121 gtcgtcctct ctgtgcttga taagctcgcc cgactggtaa tacttatagc ttctggactt
    24181 tccgatatat tcccgtttcc tgcatttctc cgcaagctct ggaatatcca aaatgcccgt
    24241 atggtcgttg atagcaaggt cgatacgctt cataatgcct ccgtctatga gtgcgtccat
    24301 aagaaagtca taccagcttc tttgctgtgc cagcaggtaa ctttcaaact gcctgcaacc
    24361 ccgacccttt aactctaaaa ggacaccttt ttcttcgtca gccgacgtat agataaagat
    24421 gtcccctaat gaataatgct ccgtataact gtaatgtccg taatcttcat ggagcatata
    24481 attgatattc agttttaata tgtctttgat gatgtgctgt atatccagcg tgggaaaacg
    24541 aattttcaca taatcaaaca gcatggtaag cggtgcttct ggattgaacc ttgccagttc
    24601 tttatgcaaa gtttccagaa gttcttttga cggcttcatt tttccgcttt ctatcttgtt
    24661 tagatattcc cttgtgatac cagaagctac cgccagcctg ccttgtgaga taccgtaagc
    24721 aatccgcttc tcccgtaatt cttttatcca ttgttcttca ttcagaacca tacccccaat
    24781 ctgtcaagtg tgaagttttt taaggcgact tcacagccga tttttactag aaaaccatgc
    24841 cagaagcctt atgtttccta tgtttttttg tctattgtct atttgcaaac gtacccctct
    24901 gttagatacc gaggggtttt acctgctggc gtggcttacg ccacaccagc aacggctagt
    24961 ccgagccgtc gcctttcgct tcgcacgtcg ccgtcccgtc ctgccttgct tgtgcaagaa
    25021 aaccgattgt ctgcaaaaaa tcatgtcctt tcgggactaa aggcgtgtaa aattcactta
    25081 tgacgcttgt tcccacatca caatagccac gccctttgat acgcttttgg aaaaactgct
    25141 ttttcacatc tgaaccaaac agcataccgt aacctaactc gctgatacgc cccaatccca
    25201 cacggaaatt gaagttatct ctgataccgt ccgagaaata ttttgcgtct ggacgctggc
    25261 aggcaacgat aaggaaataa cctgcttgtc gtcctaacat gacgattttc tttaactggc
    25321 taagtaagcc cacactttct tttgtcccca gcatttcaaa aaacgccaca tattcatcaa
    25381 agataagaaa gcagggtggc agtcccagat aggcgtaatt ttcgcccgtc ttatagttcg
    25441 ggtggcgttt catttgctcg cttcgctgta ccatgccctc ataaaaagca ttgacacagt
    25501 ctatcatttc ttctttggtg tgatacacgt ttcccatgac tgttcccaag tctgctaagt
    25561 ccgcattttt cgggtctaag atgtaaagga cagcgttggt atgcagtagg gcttcaatga
    25621 gcgtcagaag aaaatatgtt ttaccgccac cagtcccacc agcaatcaga gcgtgaggga
    25681 gtgcgtcata ttcccagaca agatttttca tcagtctaag acagccgttc tctgcccgta
    25741 cttcatcaat ggtaatgcgg ttcgctatca tatcataaag cagggtatat tcgatatagc
    25801 cgtcatgcag ggtcttgtcg gtcagctcac aatacaagcc actttccaat ttatcctcta
    25861 accgtaaaag ctggtcttga tatttcccca gcgtaatttc acagcggata tgaagcagtc
    25921 ccttttccat ttgataataa atctttggaa accagacgat tttttccctt gatctgcttt
    25981 gcaggtcagt aaaaaaaacg ctgtcttgta cggtatcagc ttcataccac ttgttttcca
    26041 gtatcattcg tgccagcttt tgacggtgca gtagcttttt gaaactgtcg taacagaagc
    26101 ggtaatacag aaaagcgacc aatgcacaaa caccagtcgc tatcagtatg gttatgaagt
    26161 tgtaaaggga aagcgtaaag ccattgtcta ataagctgaa atgttcccag tcggtacgca
    26221 tgagctgttt tgtatttaat agcaggataa ccgctacgaa cacaaacagg agtgtcccca
    26281 ttgaaaagcg atagacaagg ttcttatcgc tggctctgat acggtgtcct ttgtttaaaa
    26341 tcattctcat aaatcaatca ctcctttctg ggtatgaaaa aagcagtcaa tcgtatagac
    26401 taactgcttt gtgtgcatgg atatgaagtt gtcaaactgg aatttaacgt tcactcatat
    26461 attgttttat ttcatcagaa gtcaattttc gtacttctgt atgtggatat tctttatact
    26521 ctccaacatt aaacacaggt gtcatttgtt tgcatttctt gtctttattc tttttcaaga
    26581 atagatgtaa atcctcattc ccggcgaata ttttataaga tactctgcct ttactgttct
    26641 ctatctcata aataccacat gaacttttcg ttgtataatc ggctgttcgt aaataaagtt
    26701 ttgcaatttc caatgactta aaaggaaaat tccatctttg taatcctctg tttgggtcat
    26761 gttcaataca aatgcaacgt ccacaagttc cacaaatata ttgagtgtgg ttttctaagc
    26821 agtccaaggg atttagtaat ggtgttattc tattttcatc agagtaacat tcttcacaca
    26881 tttttctttt cgctccttat caaattctaa tttgtcgctt tcttcatacc catattataa
    26941 cagttccgta tatcctctac aacgaaaatc tattcagcaa gtctattttt tcggttgtcc
    27001 ctgcggtgta tggttctgtg aagtgcctgt gttctgattg cctttattct tcagtacaat
    27061 atcttctgcc tttacatacc agtccacatc tgcacccgta taggtttttc gtgataccgt
    27121 atcggctacg ggattgacaa gctccacgac tgcattgtaa ggaaattccc ttaacggtac
    27181 ttctggcggt acggacacgg ggataattcc accatgcaga ctgcacttca aatcatagat
    27241 acgcttttta agctgggtac tcggtgtccc gtcttcattt tgcaagaaca catcacgcac
    27301 cgctgtaaat tttaattctc caaatgtttt ctctttgtca atgacaaatc catttgataa
    27361 tctcataaat tcttcactcc tttacttttc ttcaactgct acaatatcat cagctactaa
    27421 tacataatcg gtatgtccca catccccgat tgcgtaccct ctgccgtata acttcggatt
    27481 gacaagtttt actttctgtt catacttgaa atgcttttcg ccagcctgca cgggaatttc
    27541 caccacaaca ttttcgcctt tctgtacgtc agaataaagg ttatagcttc gtctggctat
    27601 gaccttgcgg ttgtttttat ccctttcaaa gataggctcg ctttcgcctg caaattcaag
    27661 agttccaaaa gactgtgcca tatctggcac gacatatttc atttccatat tgttttacct
    27721 cgtttctttc tatatttgat aagtttatga ttgtaatttt ttattctggc ttgtctgccg
    27781 tttgacagtt tcggcggaga acgtgatttt tctttcatca taccgttacc gccttatgat
    27841 tttttcattg tacggcgttt gtaaagatat gttccagcca gtccaccagc agatgtaagc
    27901 aacatcacaa gaaatgccat gacatttgta ctgtcgcccg ttttaggact gtcgctaggt
    27961 ctgtttggct tttctggtgt ctgcggtgtt tcgagtttct ctgggacttc tggtttttca
    28021 ttaaaagtaa tcgtctgtcc ctcgtcctca atatccttat gctcggtaac tttcttcggc
    28081 tcgtctggat tgcttaaatc atacaattct tcaaaagtta caagctgttt gccgtcaagg
    28141 gaagtagcgt caaaggtaaa ggcaacttcc gctttcatag tttcgctgtc agcggtaaag
    28201 gtgtaatcac tttccacacg tttcccattg ataagaagtt ctgcattttc ttctttcaac
    28261 atctgccagc ctacaagttt gtactgtgta ccgacttcca agccctctaa ggttacggta
    28321 tcaatgattg taacgtcttt tccagcttca atctctttgt tgccgtcttt gtcggtagca
    28381 gtcgtatgta tcttgatgat acgttctgta atcaatacag tttgtccgtc gtcctcaatg
    28441 tctttgtgtt ccgcaacttt cacgggttcg tctggattgc ttaaatcgta taattcctcg
    28501 aatgttacca gatttttacc gccaagctcg gacgcattga atgtataaga aatttccact
    28561 ttcatttctt catcatcagc gataaaagta tagtcatttt ccacacgttt tccgtcaatg
    28621 ataagctctg cattttcttc ctttaacatc tgccagcctt tgagctgata ttttgtacct
    28681 tttgtaagcc cgtctaattt gacagtatcg acgattgtta cctcttttcc tgcaaggata
    28741 gtcttttcgc tgtctttgct ggtcgctgtg gtatggatag agatttcttt ttcgtattca
    28801 tcagtcaaag tccctaaatc aatcacaagg ttatttcttg ataccacgat ttcaaaaggt
    28861 gggataagtt caaagccttt gttactatcg caacgcattt cttcaatgat gtaagtatca
    28921 taaggcaatg cacctttgct gtcgtctgct tcagaagttc caaaccacac accgtcctcg
    28981 ctggtcttgc ctgcgttagt attgtgctta tgagaagtcc attcagcaga agtggagaat
    29041 tgcccattat catcagtaac tacaacatga ctttctcccg tcgtcttgct tgtgatccta
    29101 aagggaacat cagcaagacg cttgtgtgtg cctgcaccga ttttcactcc ctcaatatcc
    29161 ccacgcttaa tctgattgta gatagagtgg gcttcgtcgg ttaagtccac gatttttcca
    29221 ttctctgtga ttgcaaagtc aatcggcttc gcaccgtctg tcaagtaacc gtcgggagct
    29281 tcactctcaa cgatacggaa tttcccataa ggtaaaaggt cagcagaagt agaagccaca
    29341 ccctcaatat ctgtacgaat tgtctttacc acttcatttt tcttatatag cttgccctca
    29401 accaaaacag aattgtcatt taaggaaatg acgtcaaaag cagtatcttt caaagtggca
    29461 cttccttgtg gtttggtatc gctcgtttct aaatctcttt tctgaatttt cacaccgcca
    29521 cggataacct tgtctgatac ggaaaactgg ttacttcccg tcaatacagc aaggtcgccg
    29581 tcctctgtaa tttgtgtaag gtataagcct tttatctgtt cagacttatc gccagcctgc
    29641 atatatgcac cgtccagcaa gtagccgttt ggagcttttg tttcctcaac agatagtgtt
    29701 cctaaaggaa gaaccgcttt gccgtcctgc atatagaagc tgtcgccaga taccttgtaa
    29761 gcgtccgcta attttgtgat gtagtgagtt gtcccgtcac tgtctgtttc agcgattgtc
    29821 tttgtaaccc atgtacgagt agcttcggca gggagattgt ctttgttata gaagccagca
    29881 taatacttcc atgtaaactc tgctccctct aaagaagcgt ttccctgcgg attgtctttc
    29941 tgcgtttcca tgtcaatctt gaaaagctca atcaaggtgt ccgttacttt tggtgtatct
    30001 gatacgttca aggtcgctgt ctttccagct tcaactttta aggaatacac ggttgtatca
    30061 actttatatc ctgctggtgc ggataattcc ctaatataga ctgtacctgc ttttacctct
    30121 acaacatctg tatttccgtt tttatcagtc gtaagggtgg caagctgttt cgtgcagtcc
    30181 ttatcagaaa agacaccata ggtcgcacca gcgattgagt aattcccgtt accgtctgta
    30241 atgctggtat tactggaagt cttttgcagt tttgcatttc cgacatttaa cttcgcccag
    30301 aattgtccca attcctgccc ctcgccagag tagatataac cgccacattc atagcgtcct
    30361 ttattttctt tcacaaaggc tttagcacca gcgaaaactt cgtcctgagt tgcttttggt
    30421 atttcatcat aagaagctcg cacgttgtcg cattgccagc caagatgtac gctcaatctc
    30481 tgccagacaa cacattgttc caacagatag acttgcttgt agttcaattc cttgtgtgct
    30541 tcgccatact gtttgacata ctctaaggat aacgccacat ctgaaatctg gtcggcactc
    30601 atacgggtgc ttgcgtcagc tctggtcttg tagccattct taaaatctgt attgatgtct
    30661 atacagtaag cgtcctcgcc ctcaacagtc aaatgtccct cgttaaaggt agaaccaatc
    30721 gaaccgtcat tcattacttt ttctacgata ccgacacgtt cctctgattc cgtccagtat
    30781 tgcttgcttt ctgcatggac ggcggtactc ggtaaagcag taacgacagt cgcaaaggca
    30841 agtactcccg tacacaatcg tttcaatatc tttttcataa ttctaaatgc tcctttcatt
    30901 ttgggtaaaa aaatagacgc tcaatattga acgtcttaca ttgaaaaggg atacttttta
    30961 caagtacccc tcaaatctaa tatttaattg tttgtgttcc cacactctat atcaacaact
    31021 actgaaacat tgatatagtt ttttatctct ttatttctga ttttatcgcc ctcgctcgta
    31081 aagactatat gcttaaaaaa gtgcctaaaa ttaaggattt ctacatagtt cgtctttgta
    31141 gcaacacaca agtctctata tgtgtagaat gagggaacat atctacaggt tgtgcctcaa
    31201 cacatttaaa tccgtgaaca tttagataat ctaaatccct tgctaaagta gaaggattac
    31261 aagaaacata gacaattctt tctggattca ttgaaacaat agtctctaat accttttcgt
    31321 cacatccctt tctaggtggg tctacaacga ctacattggc agtcttaccc tctctataca
    31381 tcttaggtac aatttcctct gcctttccaa cataaaattc agcattatgt atattgttta
    31441 atttagcatt tatcttagca tcttttatgg catcatctat aatttctatt ccataaacct
    31501 ttttagcctt ttgtgccaaa aataaagata ttgtacctat cccacagtaa atatcaaaaa
    31561 cagtatcagt atcatttaaa tttgcatatt caagagcctt atcatacaat actttagttt
    31621 ggacagggtt tacttggaaa aatgataatg gtgaaatctc aaacactaag tctcctatat
    31681 aatcgtttat ttttccatct ccatatataa ctatattttc tcttcctaga atagcattcg
    31741 tatctttttg atttacattt acaaccaaag tcttaaatcc aggtatattt tccttaagca
    31801 ctgaagctaa ttctttaaga tatggaagtt tgtttccatt tgctactaat acaaccatta
    31861 cttctttagt tgtaaaacct atttttgtta ctaaatgcct aatcaacccc gtgtgagtct
    31921 tttcatcata tatgcttacc ttataggccc ttatatatgt ttttattatt ttaacaattt
    31981 tatcatttat ctcatgttgt attacgcatt tttctgtcga tattacatca tgagtcttct
    32041 ttttatagaa gccaataatt ggaataccat tattcttttg tattggaaat tgtgctttat
    32101 ttctatatct atatggatta tccattccta tagtgtcatg aacttctaca tcctctaact
    32161 tacctattct cgaaagtact tgtttaactt catttgtttt catttcaagt tgtttattat
    32221 aatctaagtc ttgtatctga caccctccac aatccctaag attgtcacta cacactcttt
    32281 tcaccctgaa tggagacttt tctattatct caacaatatc tcccacagca taatttttct
    32341 ttactttatt aatcctaact ttaactttat catgtattaa tccgccctct acaaaaactg
    32401 taataccatt gtactttcct actcctactc cgccttgacc aatgtctact atatctacaa
    32461 tatacatctc gtttttcgaa agcataaatc accctccaat caatctatta tatttaaatc
    32521 tttacaaact tttttcttta aatttatatt aaaatattgc tattaattaa actatatttt
    32581 ttactaagct acaatatttt attttaccaa aaaaaaagga gcttataaag ccccttagta
    32641 aataaattta ttatttttct tataaaactc tagttgaacc tctatatacc acgcctcttg
    32701 atgcatccac agttacaact tctccatctt ttactagatt tgttatatca gctgcagaca
    32761 caataactgg tatatctaaa tttataccta caatagctgt atgtgatgtc attccaccat
    32821 tctcagttac tacagctcct gctttttcta tataattgtt catttcagca tcagtagcag
    32881 tagaaacaag tatgtcgcct tcattaaagt ctacacaagc atttccattc tttattatac
    32941 gaactttacc ttctactgtt tgagtaccta cacctatacc ttgcacgatt tcttcgctta
    33001 ttacatgaac ctttattaaa ttagtagttc cacttactcc tactggtact ccagcagtta
    33061 taactactaa ttccccatta tctatataat cagcttgtct agctgcctca attgcctttt
    33121 ctataacttc atctgtattt cctgcaacag aagacttaac tggatatact ccccatgtaa
    33181 gagctaattt attcatagtc ttttcattat ttgtagtagc tattattgga gattttggtc
    33241 tgaatttaga taccattcta gcagtatatc ctgaagaagt agatgttatt atagctgatg
    33301 catttaaatc tactgctgtt gtacaagttg catggcttat tgcatctgtt acagtaacat
    33361 tgttagtacc attttccttt agtaatctat cataatctaa agtctcttct gttctttttg
    33421 ctattgtagc catcattttt actgcctcta caggatattt tccagcagca gtttctccag
    33481 ataacattat cgcatctgtt ccatcatata tagcattggc aacgtctgta acttctgctc
    33541 ttgttggtct tggatttctt atcatagaat caagcatttg agtggcagta acaactggct
    33601 ttgctaattc attacatttt tttatcatca ttttttgaac tattggcatc tcttcagttg
    33661 gtatctcaac acctaagtca cctctagcca ccattatacc atcagaaact tttaatattt
    33721 catctaggtt ctctacacct tcttggtttt ctattttaga tattatttgt atatcagttg
    33781 cattattgtt ctctaatact tctcttattg ctagtacatc agatgccttt cttacaaaag
    33841 aagcagctat ataatctatt ccttgactta ttccaaactc tatatcactt atatctttag
    33901 gagttattgc tggtaaattt atcttaacac caggtacatt tactccttta tgatttttaa
    33961 ctattcctga attttcaaca acacaaacta tatcttctcc atttatttct tttactctta
    34021 agccaactaa accatcatct attagtatag aatctcctga tttaacgtct tcagcaagac
    34081 ctttatagct tactgtacac atttctttag tccccataat atctttcata gttatagtga
    34141 acttttgccc ttcttctaaa aatacctctg ggtcttcaaa gttacctgtt ctaatttctg
    34201 gacctttagt atctaataat atagcaactg gcttatttaa tttttctcta actttctttg
    34261 ccatatcaat tctttcttta tgttcttcat gcgaaccgtg agaaaagtta aatctacaca
    34321 catttagacc attttgcata agttgagtta aaacttcctc actttgtgat gctggaccta
    34381 gtgtacaaac aatttttgtc ttctttacat tatttaacat atttgctcct cctgagatat
    34441 tattccacag atttattttt aatactaaaa cttatataga taatattttt gccatctcat
    34501 aagcttcttt atcaaatact ttcttttgag ctaaagcttc acttatttct aaatcaatta
    34561 ttttgttttc ttttattcct acaactctag ctgattttcc atctaataat aattctactg
    34621 ctcttactcc aagtctactt gctagtattc tatcagatac agttgggctt cctcctcttt
    34681 ggacatgccc caatacagtg actcttaaat ctgctcctga ctctttttta agttcctttt
    34741 ctaaatcact agcacttccg actccttctg ctaaaacgat tatactatgt ctcttacctc
    34801 ttttttgagt agtctttaat cttagagcaa cttcatctac tgtaatttct acttctggta
    34861 ctattatagt ttccgctcct cctgcaagac ctgcatataa ggctaaatct ccacagtgtc
    34921 ttcccataac ttctactatg ttaactcttt catgagatga tgatgtatct cttatcttac
    34981 ctatagcatc tataatagta ttcattgcag tatcaaatcc tatagtataa tctgtatatg
    35041 ctaaatcgtt atctatagtt cctggtatgc ctatagctgg gaatcctaag tcactaagtt
    35101 tttgggctcc tgcaaatgaa ccatctccac caattacaac taagcaatca attttatact
    35161 ttttaagaat ttttactgct tttaatctac cttcttctgt tttaaattct tcacatctgg
    35221 aagattttaa tatagttcct cccctgtgta taatatctcc aacagaagat aagttcattt
    35281 cagttaaatc ttcttctagt aatcccttat atcctctatt gattccatat actttgcatc
    35341 cataatatat tgctgatctt acaaccgctc taatcgcagc attcattcct ggagcatctc
    35401 ctccacttgt tagtaatcct atagttttca ttttttacct ccttggattt tatgtcaatt
    35461 ttttattata atcattgtta ttgtattcta atggactttt tttgtcccta tatcactttt
    35521 taatcccatc aagactaaaa aaattaaatg tccttaaatg tccattttgt gatattatat
    35581 cacaaaacgg acaatatttt tcatattatt ataatatatt tagattttta tataaaaaat
    35641 caagctttta cttttatgtt atctttagga agtaactctt ctaagttatt tataaattca
    35701 tcacatatac aagtcaatgc cccggtcatt ttatatgctt tacgtttacc atttatattt
    35761 tcatccatag ggtataagta tatactgtca ttacctggat attgtttggc tatttctaca
    35821 atattattag ttgtatcagt atcagacata ctatctattt tcaaatacaa ttttttacca
    35881 ctttctggct taatattttc tacatttcta gttcttcctg aattgtagtt tctatctgca
    35941 aagtcagtat catcatttat atcttttatc tctctagcta taagttttgc attttcgcct
    36001 tcttttatac ttaatgttcc ttttacatat attatattat cttcattcaa aatgacatta
    36061 tacttttgta ataattgagg aaaaactatt atttctatag caccatacaa atcttctaat
    36121 tcaataaatg ccataatttc atttcgtttt gttgttttaa tagttttagt tacaatcatt
    36181 ccacccatta taacatctgt ttcattcatt tgtaggtatg actcttcttc ctcttttaat
    36241 gaatttaatt ttccattatc catagatgtt ttttcttgta gttctttttc aaattgtgat
    36301 aaaggatgtc cacttacata cattcccaag acttcttttt caaggttaag tctctctctt
    36361 tcttcgtact cttgcctttt aggcaaactg tatatttgtt gaaaatcact atcttcctca
    36421 ctatctccaa aagcatcaaa taaagaaatt tgaccttgaa catttttctt tctatccata
    36481 gatacacttt ctaataaact ttcataacca gccatcagac tagctctatt ttcacttata
    36541 ttatcaaaag ctccacattt tattagactt tctattactc tcttatttgt atctttttgg
    36601 tctaatcttt tgactaaatc tactaaatct acaaataatc cattagattc tctttcagcg
    36661 attatattgt ttattatatt tacgccaaca ttttttacgg ctgctagacc aaatcttata
    36721 ttgtcgcctt caactgaaaa ctttgaaaaa cttttgttta tatctggagg taatacatct
    36781 atttctagtg ctttacattc tcttatatac tcaactacct tatcagtatt tcccattaca
    36841 ctggttatca atgctgccat aaattcaact ggataatatg tttttagata agctgtctca
    36901 tatgctaaaa ccccatatgc agctgcatgt gatttattaa atgcatatct agcgaagtct
    36961 atcatatcat caaatatttt attagctatt tcctcttcta caccatttct gatacaccct
    37021 gcaatttcta tattaccatc ttcatcaaat ttaccatgaa taaaatattg tctttcttct
    37081 tccatcacgt ccatcttttt cttactcatg gctcttctaa ctaggtcact tcgtccgtaa
    37141 ctataaccac ctaaatctct aacgacctgc ataacctgct cttgatatac caaacaacca
    37201 tatgtaactt ccattatagg ctttaatttt tcatgtagat atgttacatc ttttgggttg
    37261 cttttatttt ttatatatgc aggtatagaa tccattggac ctggtctaaa tagggatatt
    37321 cccgctacaa tatcttcaaa attgtctggt tttagctgtt tcataaaact tctcatgcca
    37381 gcactctcca attgaaacac ccctagtgta tttcctgatg aaagcatttc atatactttc
    37441 gggtcgtcat aatccatctt tgaaaagtct attttttctg tgtaattttt tataactcta
    37501 tttttttcta ttaaatcaag agtatctctt ataactgtaa gagttcttag cccaagaaaa
    37561 tccatcttta aaagcccaag ttcttcaagt gttgtcatag taaactgtgt tgtgattgca
    37621 tcttgatgtt tgtacaaagg tacatattca tctacgggat tttttgatat aacaactcct
    37681 gctgcatgag tagaagcatg tcttagcatt ccctctatct gttttgatat atttattatt
    37741 tcttttgttt ccgggtcttg gtcatacaat tctttaagat taggatttgt atctagggcc
    37801 ttatctattg tcattcctaa agcaaatggt atttccttgg ctaccttgtc aactttattg
    37861 tagcctatat ccaataccct tccaacatct cttattgcag cttttgcacc cattgttcca
    37921 aaagttatta tctgggctac atggtcatca ccatattttc tctttacata atctataact
    37981 tcttctcttc tctcataaca aaaatctata tctatatctg gcatggatat acgttctgga
    38041 tttaaaaaac gctcaaataa tagagagtac tttattgggt ctatatcagt tattttaagt
    38101 gtatatgcta ctatcgaacc agccgcacta cctctacctg gtcctactat aatattattt
    38161 tctttagaaa aatttataaa atcccaaaca attaaaaaat actctacata acccattttt
    38221 tcaattacat ctaattcata atttaatctc tctagtatct cattactagg attatcatat
    38281 ctctctttta atccattaaa acacaactcc cttaaataag tttctggtgt atatccttct
    38341 ggaacatcat acttaggaag atgtatagta ttaaaatcaa actccacatt acacatatca
    38401 gctattttca cagtattgtc aatagcctct aatgcatatg gaaataattc ttccatttct
    38461 tctcttgatt ttaaataaaa ctcatcacta ccaaatctca ttctatttgg gtcatttaat
    38521 gtttttccca tttgaataca cataagtaca tcatgtattt tcgaatcttc tttatttaca
    38581 tagtgaacat cattagtagc aactagtggt ataccagtct cttttgataa ttttactaaa
    38641 ccagagttta cttctttttg ctcaggtaaa ttgtgatctt gaatctccaa aaagaaattt
    38701 tcttctccaa atatgtctct gtagtcaaga gcaaattgtt ttgctttttc ataatttcta
    38761 ttcattaaag cacgtgctac atctcctgca aggcatgcag aaagtgctat aatccctttg
    38821 ttatgttttt taagttcttc catgtcaact ctaggcttat agtaaaaacc ttctacgtat
    38881 gaagttgaaa ctatttttat taaattttta tatccttcca tattcttagc taacagaact
    38941 aaatgtcctt gatatttgtc atagtttggg tctttatctc tcaatccacg tgcagctgta
    39001 tagacttcac accctataat tggctttatt ccttctttta tagctgtttt gtagaaatct
    39061 ataacaccaa acatacaacc atggtcagtt atagctattg agctcatgtt tagttcctta
    39121 gcccttttta taagtttttt caccctcgaa aacccatcaa gtaaactata ctcagtatgt
    39181 acatgaagat gagcaaaatc tttgttcatt aaatcacctc ctgctttata attttaattt
    39241 taccacaaat atatgtccta aaacaaaaac agagactttt atctcaaaat aggaattaac
    39301 ttcaacgtat accattatat gttataaatt aatgcttatt ctgagattgt cccctcaatt
    39361 tattgctatg attttttttt caaatctgtt gcaatttctt ctatttttct aagtctatga
    39421 ttgactccag attttcctat tggtggttct aacatctctc caagttcttt gagagtcata
    39481 tcctcatact cgattctaat cttagctatc tcttgtaaat tttctggcaa actgctaatt
    39541 cctatagtct cttgtatgag cttaatattt tctacttgtc ttactgctgc atttactgtt
    39601 ttagaaaggt tagctgtctc acaatttact atcctgttta cattatttct catttctttt
    39661 actattttag tattttgaag acttaaaaga gcgtggtgtc ctcctataat actcaacaaa
    39721 tctgatattt gttcactctc tttgatataa acaacgtgat tattttttct agccacaatt
    39781 ttactattaa aacctaaaga gtttataagt tcttttagag aatctgcaaa ctcctcatta
    39841 ttagttacaa attccatatg atagttcttt tctgggtcgc ttatagaacc tccaccaaga
    39901 aaagctcctc ttatgaaagc tctcttacat ccttcatgct taattaagtt ctctgaaatt
    39961 ttgtttatag taaaaaatcc ttctttatct tcaagtatac ctaacttttt taataacatt
    40021 tctgaaccca tttcgcttgt taccattaat acataactgt tatttctctt tagcatttga
    40081 ttcttattta ctgagattgt agtattgata ttaaaattct tttttaataa tttaaatact
    40141 ttacgggcta ttgaatttaa ctctgttgtt atctttagat ttagcttctt atatccaaca
    40201 atttgtatac ttccccctga tttaactaga gctgacaatt cagctatatt acaacattca
    40261 ttcccagata taactcttgc tagttcattt ttggtttcag ttgaaaaaga catatctatc
    40321 acctattaac taatttttct ttaacctttt ttttatttct tgtaaggcaa cctttattat
    40381 ctccttttca tcatcatacc tagctaagtc tactactcta tctaggtgga taaatttagc
    40441 atcaataaag ccttcctctt tttgtggaat agtatccata ttctttgctt gcatcaaata
    40501 ccaaaaaact gttttatgaa ctgctctatt ttcatcccag ttttctttga atgtatagtg
    40561 tatttcacct aaatatttca atatatctgc ttttactcca gtttcttcac ttacttcacg
    40621 taatgctgcc tcttggttat tttccccttc ttctactttt cccttgggta acacccaatc
    40681 tccattgaac ttccttagta aaagaatcgt attgccaaac aggactacac caccagcact
    40741 aacctcttct ctcatcgatg ttcactcctt aaaactaaca taatgataag gatttctaca
    40801 caatttttta aaatcctttt ttactaactt ttgttgtaat tatgatttag ggctaactca
    40861 ataactatgt tagatatata ctttgcatca tgtcttatat aattattttt tatttcaatt
    40921 aaattcttct ctacagtttt tatacccatc tcttttaatt tatctttttg ctttttatct
    40981 aacaagactt gctctgctcc atcttgttta tataagtcaa gcatttcttc tggcaatatc
    41041 tcattatttg cgattacata atctattaaa ttctcatcag tgtgttttac tatagcatta
    41101 acatgctcta atacattgta cccttctgtc tcacctggtt gagtcattat atttgctata
    41161 tatacttttg gagctacaga cgatttaata gcgtctacaa tcccctctac aagtaaattt
    41221 ggtattatac ttgtatataa acttccagga cccataatta taatgtcagc atcataaata
    41281 gatgcaataa catcctttaa tggttttaca tcttttggat ttaaaaaaat tttatcaata
    41341 gagctttttt gaatttttga ctcttcaggt atactagatt ctccatttat tatattgcca
    41401 ttttctaatt tggcaactaa atttacatct tccaaagtta ctggtaaaac tcttcctgtt
    41461 atagcaaaaa tttcacttaa tttatataca gctttttcaa agtttccata caacccattc
    41521 atagcagcca aaaacaaatt tccaaaactc tgacctttta aaagcccttc tgtaaaccta
    41581 tattgcataa cttcattcat tgttggctct atatttgcaa gtgctaataa acagtttctt
    41641 atgtctcctg gtgggagcat tcctaagtct tctctcaata cacctgaacc tccaccatca
    41701 tcagcaacag ttacaattgc agttatattt tgcgtagtgt gtttaagacc tcttaaaaat
    41761 accgattgac cagtacctcc acctatcaca accacatttg gttctctatt ttcaacaata
    41821 gacctttgaa atagttttac tttttcattt tttgcttttt tatatataaa taacgataca
    41881 attaatgcaa tccaacctaa aattcctaca ataataagta atttagccat gtttgcctcc
    41941 attatcgcaa catagagtct ctatgtttct ttacaactct atatccctta ttagataaat
    42001 cctccgctat aagatttgtt atagtaactg acctatgtct tccacctgtg catccaacac
    42061 caattactag atgttgtttt ccttcctcta tatattgagg tactaaaaaa tgaatcatat
    42121 ctaaaagttt cacataaaat tcttcactga ttttagaatt cataacataa tctctaactt
    42181 ctttatcatc accagtttta gctcttaact cttcaacata atagggattt ggaagaaatc
    42241 ttacatcaaa tactaaatct gcatcagcaa gtataccatg tttaaatcca aaagatacta
    42301 cagaaatagt taggtttgga ttatcttcac cagaagaata tattttcttt atttcttcct
    42361 taaggtcttt aggtttcatg ttagttgtat caattataca tgtagataac tcctttaaag
    42421 gttccattat ctttctttcc atttttatac cttctggaat ctgcatatct tttgccaatg
    42481 gatgatttct tcttgtcatt ttatatctct ttagcaatac atcatcatta caatccaaat
    42541 ataccatttc atattcataa ttttcttttt ctaaataatt taagctttca tgaagcgctt
    42601 caaaaaactt tctccctctt atatctatcc ctagagcaac tttatcaata cttgaatttg
    42661 gttgataaca taattctgca aatttagtta tcaaagcagg aggtagatta tctacacaat
    42721 aaaatcccat atcctctaaa gctctcattg tctcactttt tccagatcct gaaagacctg
    42781 taactataac aaatttcatt gctaactcct cccttttatc ttatgtttat tatattataa
    42841 tgttttctac taacgatata tccagattag agtcagatat agtcttcata gctagttcaa
    42901 aatcaccaac tctttctgga caatgtgcat ctgagcctat tataaattta ttttctagcc
    42961 cttttatttt atttaattga tttacattca aaaaagaatg gctactattt atctcaagtc
    43021 tagtatttgt cttttttgct gtctttgcta cttcttctat atacacatcg cctttatctc
    43081 ctggatgagt aattataaaa atatcattat tacttatcgc atttattaca gcttttgtat
    43141 tatattcttt tgctttttca gttttaaaaa tatagttatt acaatgattt aataagcttc
    43201 ttaatgatgt tggagtagaa ccaaaatgat atccagccat aatataatca aaatctctaa
    43261 taaatttatc atccatatct atatttcctt tatcatctaa tatgttacac tccataccta
    43321 aaagtatatt tatatcagtg tacttatcat ttaaataatc tacttcttct ctcattttga
    43381 gaatatcttt tttctttaca ccatatgcaa tatgtttata actatggtca gatattccta
    43441 ttgtttttat tcctttagaa atggctacct ttacattatc ctcaatagtc cctttgccat
    43501 gactatataa tgtatgtgta tgataatcag ccagtatttt catttgttaa tcctctccaa
    43561 gtattttgac ttcttcttcc aacataaccc caaacttggc atatacagca ctttttataa
    43621 catatattaa atccaaaata tctttagcac ttgcttctcc ttgattgact acaaatccac
    43681 aatgcttctc agatacttgt gctcctctta aagtaagacc tctcaatcca gtttcttcta
    43741 ttaatttacc tgcaaaatat cctgttggtc tcttaaatgt acttcctgca ctagcaaaat
    43801 ttaatggctg tttagttatt cttctcgtcg ctaaatcatc cattaaactt tttatttcat
    43861 cataatttcc ttcttgtaat tctaattctg ctgataaagc tatatatccg tttttcgata
    43921 ttatactttt tctataccca aattccatct gttcatttga taattcaaat atattgcctt
    43981 ccatatccat cagtcttact gacttcacta tatccttcat ttcaccacca tatgctccag
    44041 cattcatggc taatgctcct cccaatgtgc caggtattcc tgatgcaaac tcaaaccctt
    44101 ttaattcttg cttttggaga gctttcccta aaactgataa taaagctcct gactgagcag
    44161 tcatcctagt atcatttatc tcataagaat tgaaattatc agctaattct attaccactc
    44221 ctcttattcc accatcttta attaaaatgt ttgaaccatt tccaattatt aaatacggaa
    44281 tagactcttt ttttaccaac ttaagtacat tttttaattg ttcttcagtt ctaggtctaa
    44341 ctaatatatc tgctggtcct cctaccctaa atgaaatatg ttttttcata ggttcatcga
    44401 cttttatatc ctctttactt aatatattta ataaatttat atatatatct tgattattca
    44461 ttgtatttcc tcccaaatta tactgaactt tagctgtcat tattatttaa attacattaa
    44521 tatatagtat taactatatt caataatata tgattttgct tatcatatgg attttatatt
    44581 ttaagcttct taattacaaa ctatattcaa taaatatata ataaagtaaa aaaaaaaaaa
    44641 taacaacata taaaagaata taaataattt aaaaaaagca tcaatatcac tgatatcaat
    44701 gctttaaaag gcaatttaat tcgtattatt tatctaacta tttttgacat agcaaagata
    44761 ataaatccct ccaactacta tggaacctcc aacgatattt ccaagtgtta caaataccaa
    44821 attagttata aattgaacca tagttatatt tgctcctaat gccattccca ttggtataaa
    44881 aaacatgttt gcaacactat gttggaatcc acataataca aatagcatta ttactgtcca
    44941 acatgaagcc aattttgaca ttatatcttg agatgctgta gccatccata cagctaaaac
    45001 gactagaata ttacaaagta ttgcttttaa aaacattgat gctatagttg aattaacctt
    45061 agcttctgcc acagctatag cttttgtagc tgcatctcct gtcaatgtag aagaataaaa
    45121 cacaagtgca actagcaaaa ttgaacctac taaatttgca aaataaacca gtccccagtt
    45181 tcttaacatt tttcctaatg ttattttttt gtccataagt gcaatagcca ttaaagtgtt
    45241 tccagtgaat aattctgctc ctgccactac tacaagcata agacctactg gaaagaccat
    45301 agcacttaaa aagctagcta cccctgggtc tatcttgcca aaagtttgac taactatcat
    45361 actccccaat gccccaaaac ctataaatgc tcctccaaat aaacctaata gaattgcatt
    45421 ttgtgtcgaa atatttgctt ttttaatgcc tgcacttata gttgcttgtg cagtttcccc
    45481 aggtgtcaag aatcctttac tcataaatcc ttccccctta aaaattatac tttcccttgt
    45541 ctttttatgg caataattat ataataacaa tatgatatat aataaatttt attaacataa
    45601 aaaat
//
LOCUS       DAEPXW010000027        42066 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.028, whole genome shotgun sequence.
ACCESSION   DAEPXW010000027 DAEPXW010000000
VERSION     DAEPXW010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42066
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.028"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            98..2287
                     /locus_tag="KRM55_001406"
     CDS             98..2287
                     /locus_tag="KRM55_001406"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBH1593655.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            2355..3122
                     /locus_tag="KRM55_001407"
     CDS             2355..3122
                     /locus_tag="KRM55_001407"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBH1593656.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            3180..4196
                     /locus_tag="KRM55_001408"
     CDS             3180..4196
                     /locus_tag="KRM55_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH1593657.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            4262..4510
                     /locus_tag="KRM55_001409"
     CDS             4262..4510
                     /locus_tag="KRM55_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593658.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(4686..5183)
                     /locus_tag="KRM55_001410"
     CDS             complement(4686..5183)
                     /locus_tag="KRM55_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH1593659.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(5427..6491)
                     /locus_tag="KRM55_001411"
     CDS             complement(5427..6491)
                     /locus_tag="KRM55_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593660.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAINLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            complement(6494..7591)
                     /locus_tag="KRM55_001412"
     CDS             complement(6494..7591)
                     /locus_tag="KRM55_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593661.1"
                     /translation="MKLYMSVKTMLKGLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(7605..8540)
                     /locus_tag="KRM55_001413"
     CDS             complement(7605..8540)
                     /locus_tag="KRM55_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593662.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLILEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSIIDKNDSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(8669..9316)
                     /locus_tag="KRM55_001414"
     CDS             complement(8669..9316)
                     /locus_tag="KRM55_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593663.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(9309..10472)
                     /locus_tag="KRM55_001415"
     CDS             complement(9309..10472)
                     /locus_tag="KRM55_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1593664.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            10656..11000
                     /locus_tag="KRM55_001416"
     CDS             10656..11000
                     /locus_tag="KRM55_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBH1593665.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVASYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            11031..12632
                     /locus_tag="KRM55_001417"
     CDS             11031..12632
                     /locus_tag="KRM55_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBH1593666.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     RKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            12651..13751
                     /gene="dprA"
                     /locus_tag="KRM55_001418"
     CDS             12651..13751
                     /gene="dprA"
                     /locus_tag="KRM55_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBH1593667.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            13784..15871
                     /gene="topA"
                     /locus_tag="KRM55_001419"
     CDS             13784..15871
                     /gene="topA"
                     /locus_tag="KRM55_001419"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBH1593668.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            16036..16821
                     /gene="codY"
                     /locus_tag="KRM55_001420"
     CDS             16036..16821
                     /gene="codY"
                     /locus_tag="KRM55_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBH1593669.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            16928..18193
                     /locus_tag="KRM55_001421"
     CDS             16928..18193
                     /locus_tag="KRM55_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBH1593670.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDVEKGL
                     KRAVEVLNEDSYMDIECNNDAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            18224..18994
                     /locus_tag="KRM55_001422"
     CDS             18224..18994
                     /locus_tag="KRM55_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1593671.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            19103..19549
                     /locus_tag="KRM55_001423"
     CDS             19103..19549
                     /locus_tag="KRM55_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH1593672.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            19567..20760
                     /gene="nifS"
                     /locus_tag="KRM55_001424"
     CDS             19567..20760
                     /gene="nifS"
                     /locus_tag="KRM55_001424"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBH1593673.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGIAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            20814..21254
                     /gene="nifU"
                     /locus_tag="KRM55_001425"
     CDS             20814..21254
                     /gene="nifU"
                     /locus_tag="KRM55_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBH1593674.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            21543..22622
                     /gene="mnmA"
                     /locus_tag="KRM55_001426"
     CDS             21543..22622
                     /gene="mnmA"
                     /locus_tag="KRM55_001426"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBH1593675.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    22765..23003
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            23071..25710
                     /gene="alaS"
                     /locus_tag="KRM55_001427"
     CDS             23071..25710
                     /gene="alaS"
                     /locus_tag="KRM55_001427"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBH1593676.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEGITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            25735..25992
                     /locus_tag="KRM55_001428"
     CDS             25735..25992
                     /locus_tag="KRM55_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBH1593677.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            26002..28173
                     /locus_tag="KRM55_001429"
     CDS             26002..28173
                     /locus_tag="KRM55_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593678.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            28379..28804
                     /gene="ruvX"
                     /locus_tag="KRM55_001430"
     CDS             28379..28804
                     /gene="ruvX"
                     /locus_tag="KRM55_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBH1593679.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            28882..29169
                     /locus_tag="KRM55_001431"
     CDS             28882..29169
                     /locus_tag="KRM55_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBH1593680.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            29451..29909
                     /locus_tag="KRM55_001432"
     CDS             29451..29909
                     /locus_tag="KRM55_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH1593681.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(30026..30763)
                     /locus_tag="KRM55_001433"
     CDS             complement(30026..30763)
                     /locus_tag="KRM55_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH1593682.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            30980..32656
                     /locus_tag="KRM55_001434"
     CDS             30980..32656
                     /locus_tag="KRM55_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBH1593683.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            32862..33062
                     /locus_tag="KRM55_001435"
     CDS             32862..33062
                     /locus_tag="KRM55_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBH1593684.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            33116..34279
                     /locus_tag="KRM55_001436"
     CDS             33116..34279
                     /locus_tag="KRM55_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1593685.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGTVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(34490..34912)
                     /locus_tag="KRM55_001437"
     CDS             complement(34490..34912)
                     /locus_tag="KRM55_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBH1593686.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(34933..35769)
                     /locus_tag="KRM55_001438"
     CDS             complement(34933..35769)
                     /locus_tag="KRM55_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1593687.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIILDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            36067..36663
                     /locus_tag="KRM55_001439"
     CDS             36067..36663
                     /locus_tag="KRM55_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBH1593688.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
     gene            36693..37412
                     /locus_tag="KRM55_001440"
     CDS             36693..37412
                     /locus_tag="KRM55_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBH1593689.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            37414..37953
                     /gene="scpB"
                     /locus_tag="KRM55_001441"
     CDS             37414..37953
                     /gene="scpB"
                     /locus_tag="KRM55_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBH1593690.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            38115..38744
                     /locus_tag="KRM55_001442"
     CDS             38115..38744
                     /locus_tag="KRM55_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBH1593691.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            38698..39126
                     /gene="ytfJ"
                     /locus_tag="KRM55_001443"
     CDS             38698..39126
                     /gene="ytfJ"
                     /locus_tag="KRM55_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBH1593692.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            39374..39814
                     /locus_tag="KRM55_001444"
     CDS             39374..39814
                     /locus_tag="KRM55_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1593693.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            39830..41281
                     /locus_tag="KRM55_001445"
     CDS             39830..41281
                     /locus_tag="KRM55_001445"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBH1593694.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKIKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(41372..42040)
                     /locus_tag="KRM55_001446"
     CDS             complement(41372..42040)
                     /locus_tag="KRM55_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBH1593695.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
BASE COUNT        16871 a         4459 c         7263 g        13473 t
ORIGIN      
        1 ataattaata tgaaaatata caaatatata aaaagtttgt ttagagttat agttaatgtg
       61 tgtattaatt taatactaat ttattggagg tttaaaaatg aagtacataa taaaaagaga
      121 tggtacaaaa gaacttttta gtaaaagtaa gattgaagat gctgtctata aagctagtat
      181 aaatagtgaa ggtggcgtag atagagagtt ggcatatgat atatcaagaa aaatagctaa
      241 tgactataat tctatggaaa aatgcttatc cgtagaagaa atacaagata tagttgaagt
      301 actacttatg gaatcaaata gaaaagatat agcaaaacac tacatattat atagagaaag
      361 acgctctgaa ataaggacta aagcttggga gtttgatgaa ttacaaaaat caatatggaa
      421 gaacaagtat agacataatg gtgagagttt tgatgaatgg ataaagagaa tttcaaataa
      481 tagttcaaga atatcaaaac taataagaca aaaaagattt ctatttgctg gaagaatttt
      541 agcaaataga ggattacaga aagagggaaa aaaagtaaca tattctaatt gttatgtaat
      601 agaaccacca aaagatagca tagaagatat atttgatact gcaaaaaaac ttgctagaac
      661 ttttagttat ggtggaggag ttggaattga tatttcaaag ctaagaccaa aaggagcgaa
      721 agttaacaat gctgcaaaac atacgactgg agcagtctct tttatggaac tttacagtat
      781 gacaactggc ttaattggtc aaagagggag aagaggagct cttatgattt ctatggatgt
      841 aaatcatcca gagatagaag actttataga tataaaaaca gatttggaga aggttactaa
      901 agcaaatatt tctgtaagag taacagatga atttatgcaa gctgtaagag aaaaaaagtt
      961 atataattgt acttttgaag ttgaaactac tggagaaaaa atagttaaga tagtaaatgc
     1021 ttatgattta tttaataaat ttgtgaaaaa taactgggat tatgcagaac caggtatatt
     1081 gttttgggat aaaataaaaa catataattt tatgagtgaa gataagaact tttgcttttc
     1141 aggagtaaat ccttgtgcag aagaaccact tccaagtgga ggaagttgtc tacttggctc
     1201 aataaacttg tcagagttta taatacaacc atttggtgaa catgctactt ttgatattaa
     1261 taaactaaaa tcttgcgtta gagaagctgt agtagcttta aatgatgtct tagatgaggg
     1321 attgaacttg catccattac aagaacaaag agatagtgta cataagtata gacagatagg
     1381 tttaggtgta atgggtatag ctgatatgct tataaaaatg ggaataagat atggttctga
     1441 tgaatcttta gaactatgtg atttaattgg taagactatg ttaaatgaag ctgtgaagca
     1501 atcagcatta attgctaaag aatatggaac atttagtgag tataaatatg aaaatatttc
     1561 taaatctaag ttttttatag aaaatctaaa tgaagacact aaggaaatgg ttaaaaagta
     1621 tgggcttaga aattcacaac ttttaaccat acctcctaca ggttctatat ctacaatgat
     1681 aggtatcagt ggtggaatag aacctatatt taatctttca tatataagaa aaactgaaag
     1741 cttgcatgat gaggatgtgt attataaagt atatactcca attgttaaag agtatatgga
     1801 caagaaaggt attacagatg aagaatgttt accagatttt tttgttactg ctatgaatat
     1861 aggatatgaa gaaagaataa acatgcaaaa agtatggcaa aagtatattg atgcttctat
     1921 atcatctaca ataaatatac cttttgaaac tacagttgaa gatgttttca atatatatat
     1981 taaggcatgg gaggctggtc ttaaaggagt aacaatattt agagatggat gtaaaaggag
     2041 tggaatttta ataaatgaaa aaaaggaaga aaataataaa gaagataaaa aagaaaatag
     2101 taaaaaagaa tattataaaa ataataaaaa agaaaaagat aataaagatg aaaaagccaa
     2161 agaaataata aataaaaatt ttgaagaaga tgaaaaattt gtgtgccctg agtgtggaag
     2221 tgaaggaatt gcacatacag gtggatgtag tatatgttta aaatgtggct atagtggatg
     2281 caattaaact ctaattaaaa aattttaata tattaaaaaa ttaaattttt aaaaacgaaa
     2341 gatgagggaa tggtatgcag gataaaagtg tgagggagat taaagaaata atagagactt
     2401 tagaagtaga aaaatatatg gaatatatag agctgttaag agttgatgaa agaaaatctg
     2461 tacaaggtct agctataaaa ctagcaaaaa agctggataa tattagaaaa gaagaagaaa
     2521 gattggaaac tataaatata tttgagaacg aaggctatga taaaggttat ttatatattg
     2581 gaggaattga tgaggcggga agagggccac ttgctggacc tgttgtagct tctgttgtag
     2641 tatttaaaaa agataccaaa atagaaggtg taaatgactc taagaaactg agtgaggcaa
     2701 aaagagatga actttttgaa gtaataaaag aagaagcact agattatgga ataggtatag
     2761 taaacaatga agaaatagat gaatttaata tattaaatgc tacatatatg gcaatgaaaa
     2821 aggctataaa ttgtttaaaa aaagcaccag attatttatt agttgatgca gcaacaatac
     2881 caggtattga catatctcaa aatccaattg tgaaaggaga ttcaaaatct atatcaatag
     2941 cagcagcaag tatacttgct aaagttacta gggatagtat aatgtaccaa tatgatagag
     3001 tatacccaga atatgggttt aaatctcaca aaggatatgg aactaaagaa cactatgaag
     3061 ctattgaaaa atatggcata actcctatcc acagaaaaag ttttttgaaa aatatactgt
     3121 aaatataata tgatataatg tatataatat aaattactat agttaatggg ggattaaaga
     3181 tggaatataa tgaattatta aaaagtgcta gagaaaattt aaatggaagt tgtaaagttt
     3241 gtaaggtttg taatggggtt gcttgtgcag gtgaagtgcc tggcatggga ggtaaaggaa
     3301 gtggttcttc ttttatagaa aatagcaaga gtttagaaaa agtaaaagta aatatgagag
     3361 taatacatga tgtatcaaat cctgatacat ctatagagat gtttggaaag aaaatgagtg
     3421 cacctatatt tgcagctcca gtaacaggaa ctactttaaa tatgggtgga aaaattaatg
     3481 aaagagatta catagaacca gtagttgcag gatgtgctaa tagtggtatt tatgcaatgg
     3541 ttggtgatac ggcagtagat gcttttttaa tggaaaattt agatgtagtc aaaaagtata
     3601 atggagctgg aattgtattt attaaacctt gggataatga aaatattata aaaaagataa
     3661 gattagctga agaagctggt gcatttgcag ttggagttga tatagatgcc tgtggtctag
     3721 taactttatc attacatgga aaaccagtac ttcctaaaaa tgttaaacaa ataaaggagt
     3781 tagtaaagtc tactaaacta ccatttatat tgaaaggtat aatgactgtt gaagatgctt
     3841 taatggcagt agaagcaggt gtggatgcaa tagtcgtatc aaatcatgga ggaagagtgc
     3901 ttgactgtac accaggagca tgtgaagttt taccaaaaat tgctgatgct gttaaaggta
     3961 aagttacaat acttgcagat ggtggagtga gaactggttt agacgtacta aaaatgatag
     4021 gtttaggtgc agatgcagta ttaataggaa gaccttttgt gactgcttct tttggtggtg
     4081 caactgatgg tgtagaaact tatgtaaata aacttcaatc agagctaagt agttctatga
     4141 tattaactgg atgtcaaact ataaaagata ttgatggaaa agttatatac aaataaaatt
     4201 ttatacaaaa aagaggaaaa atcattttaa tgtagaataa ttgtacaaag ggggaattta
     4261 tatgagtaga aaagcttatg aagaagcctt agtagaatta gaaaaattta ttgatgaaag
     4321 aaaagaaata attaaaagtg cggaggactg tattgataag tacatagttg acagaacgct
     4381 accttttgat tacaaagata aatgtgtgga atggcaacaa gagttacttg atattgcaga
     4441 ggcacaagtt ttagaagcaa atgaattaag tgtattatta caagagaaaa aagaacttga
     4501 agaagattaa attttattag ctaagagtaa atcagtaata tgatttactc ttagtttttt
     4561 ttatttgaat aaaatacatc tatctaattg agataacttt attaatatta gattaggcag
     4621 tttaaaataa gctaaagtag catggatgat tagtataaaa aataaaacca gtttaaaaaa
     4681 ctggtttaat ttgtattctt tgaatttaat atatgttttt tcatttcctc taataccatt
     4741 gtataggatt tacattgagc agcagctaat tctgataaag caaatttttg agctttattt
     4801 aaaaactcct tatctgtgct acacaattgt tttgaactgt cttgtatcat aagcattttg
     4861 attaatttta caatttcaaa aacatctcct gaatgaaatt tatcttggta cagtttaagt
     4921 ctttcttttc tatcaaaaat ccatacacca tctgttttat taatagattg gataaaatta
     4981 tcaacatcat ttccatccat aactggacgt atgccaattc tatctgcatt tagaactgga
     5041 atcgaaattt taaggttact attaaaaatg acacttaatt catagtattt ttgcatctca
     5101 tgatttattt tctttgttac aatatcattt acagagcagg ctccctcttt tggatacatt
     5161 acactttcac caattttata catatgctag ttatacctcc aaattgaatt ttagatattg
     5221 caacttaggt acaatgcttt aattatctaa tgattaatat tataacataa ataacttgac
     5281 aagtcaaaaa tattaatata taatataaag tttagacttg gtgatgtgtg aaactaaaga
     5341 gaaaaatata agataaaata atttaatatg ttgaaatatt cttttacaat tatataaaaa
     5401 tagatactaa ttatatttaa taattattag tttttagcaa aatctcttag tttaagactt
     5461 cctgcagtta caaatataat tccaattaat attagagcta ttatatttat taaaatacta
     5521 ccattgtttt taatagcatc tatagtccaa taaaatggtg tgaactttga aagattagtc
     5581 ataaaggata atttatccat tgatggtatt agactagaga tagatatagc tagacctatt
     5641 aaagaataaa atgtagatat aagacttata gaactttcat ttttaaatac tctagctacc
     5701 caaaatacaa atccagtgga aacaaaacta tttgctagta caatcatcaa tacattcaga
     5761 ctcaaattaa agtcttctat aattgaaaaa cataatagag caaaagtgta tacaattgat
     5821 tgaataaaaa atagtcctaa aaatatactg aaaattattt ttatatcttt attatctgta
     5881 gagataagtc tttttagcac atttgatttt tttaatgtaa ataaatcaga agcaagatgt
     5941 gccgcattaa tatacataaa atagcatatc aagaagacta ctaaaaatga acctttattc
     6001 ttatctggtt tgttatcaat tatatttgtc tttgtcaatt tatcatctat atttttatcc
     6061 actttcaatt ttaacgattt agtaataaaa gattctattt gtgattctgc ccaaagacta
     6121 ccaccaccat tttcaatttt aaagcattta actacaggtc gttgtaattt atctatacta
     6181 tttgaaaaat ttttatctaa aacgaataca gcagaaacct tattattttt taatagattg
     6241 atagccttat cttgttcatt taatctaaat gaattttctt ttaatttaga actatttatt
     6301 aacttatgtt catactttcc tgaagagtca gatacaattg ctactggaga aaagtacatt
     6361 gattgatttc ctgagttgtt gataaaaaaa ttaagtgaaa aaattagtat aataggaagc
     6421 ataaccatat taattaaaag agtatgattt tttagatatc tttttatatt tgcaatagtt
     6481 aatctaatca ttattaaacc tccctccatt tatatttttc ctttacaata gcaagtgcaa
     6541 ttaatattgt agagataatt aaacatgtga aaattaaatc tcctattgaa tctatggttt
     6601 taaatgtttc ataattacta aacaattctc ctattaaata ggtaggagat aaacttgtaa
     6661 gcttagtaaa tgtatcactt atcatactga agatacctcc aaaaattgtc tgtaaaaaga
     6721 gtaatgcata aactattgct gtaccgtatt ttttgctaaa aaagctggtt acaaaggtag
     6781 atattgaagt cataaaataa gatgataaag cacaaagtag gagcaatatg gcaaaattac
     6841 ctttaaatgt tattccaagt attctaaaga ataaaacata taataataag aatataaatg
     6901 aataaatcca taaacctaca aagtcataaa ttaagaactg tactctagtt ataggcatag
     6961 aataaagtct ttttgaaagt ccctttgatt cacttatata atttgataaa atattgttca
     7021 ttataaaaat tattacaaga aatcctagtg aaactaaagc aaagtattca taagagctct
     7081 gtttaacatt gttatttatt atagaagtat caatagaatt tttattaaat aatttagaaa
     7141 aatcttctga acttattttc tgagaattat ttaaataaaa tttttcatgg taagtatcta
     7201 atatatcttg aagcaatatt gcaatatcat cacgagttcc aagtttttct atgtttagag
     7261 tatttgattt ttcatttaat aaactactct catagccttt aggtatagta agctttaatt
     7321 ctgccttaga atcatctttt ttaactgtta atatataaga taaatcattt ttcaaatact
     7381 ttgtcaaatc atttgataat cttgtgttat ctttgtcata tataacaatg ggggtagatt
     7441 ctgtttttat agggttttga aacatgcttt ctgtaaccat cccaagaaac caagataaaa
     7501 tcagaggcaa agctaaaaaa tatattaaat taagtataaa ggagcttttt aaacccttta
     7561 gcatagtttt tacactcatg tataatttca taaaatcacc tccattagtc ccttaaattt
     7621 ttgcctgtta gatttaaaaa tacatcttct agactaggtt cttcataaga aattttcatt
     7681 atttttgaat cgtttttgtc aattatagag agtatatctg taagttgtaa ttttttatct
     7741 atatccaatt ctaataatga attattttct aaaacagata taacaccttt agtatttttt
     7801 aaatcaaaga taagttgagc atttatattt tttatttcca gaattaattt tgtatttgta
     7861 gatactagtg attttaaata atcattatct ccaaaagcaa tttctttacc ttcatccata
     7921 ataaaaattt tagaacaaag gtgttcaact tcttccatat aatgggaagt atatattaca
     7981 gtagtttcat gttttttaga tatatctttt ataaaattga aaatatgatt tcttgattgg
     8041 gggtctacac ctacagttgg ttcatccaat attaatattt taggatgatt taagagtgct
     8101 attccaatat ttaatctcct ttgcatacca ccagataatt ttttgacctt tttctttttg
     8161 acttcagtaa gacctgtaac ttctaatgct tcaatgattc tttctttaag tagttttccc
     8221 tttaaaccgt agaaagctcc aaagtactct aagttatcaa aaggagtaag agtttctata
     8281 attgctaatt cttgtggaac taaccctatt atagactttg cttttatata atcttttgat
     8341 aaatctaaac cattgatttg aatactacca ctatttggta acataagatt tgtaattata
     8401 tttataagtg tagatttacc tgcaccattt gggccaataa gtccgaatat ctcacctttt
     8461 ttaacagaaa agctgatgtt atcaagtact aatttatcat taaatctttt tgttatatta
     8521 tttactctga ctatatccat agtaatccct ccaaaataat tttgtataag ttaaaaagct
     8581 ataatattat aataaagaat tgtgaattat aattctatta ctataagtca ctaaaaaaag
     8641 tgacttaagt cactttatat ttttagattt attctattac aattttattt ttgaaagcaa
     8701 agattgctag ttgagttctg tcacgaagtt ctagtttagc taaaatatta gttatgttat
     8761 tctttattgt accttcagat aagaatagtt cttgacttat ttctttatta ttaagtccat
     8821 ttgcaattag tctaattata gatatttctt tttctgttaa attgtacatg tcataaagat
     8881 gctcttgttt aaccgttttt tcagaggtca tgattttttc agctacactt ttatcaagca
     8941 caatattgcc aaaaaatgaa gaacgaatcc cttcatgcaa tacttcatca gagctatctt
     9001 ttaaaaggta tcctgaagca ccaaacttca tagcatcttt tatatattca tcatcattaa
     9061 aagttgttaa aattaataat gttatagaat tattatattc ctttataagc cttgtaccta
     9121 gaaccccatc acatactttc attcgtatat ccataagaac tatgtctaca tcattcattt
     9181 tacaaaattc taaagcttca tatccattag aagcatctcc tacaatttct aaatcattat
     9241 aagatgataa tataatttta agaccttttc taattaattt ttcgtcatct actataagaa
     9301 ctttaatttt attcaaaaaa atcaccccct gaaaatttag gaaaagaagc tctaattgtg
     9361 aaaccattat tagaattatc aaattcaact ttaccattta attcatatat tctctcgttg
     9421 atactattaa gtccatttcc tttttttata ttgccacatc ctataccatt atcactaata
     9481 gtaattataa gatttgaagt attgaatgta ataaaaattc tgatttcagt tgcctttccg
     9541 tgcctagatg agttggaaag ggattcctgt atgagtctat ataaagctat agattgattt
     9601 ctggataagt tccaagtatt ttttgaaata gttaatttaa cattaatatt tgtaagctta
     9661 ataaagcttt taactaattc tttgatttta aataaacttt ggtaattttc atattcaaca
     9721 ggttttaact cagatatagc ccttcttaca tcttgaaaac tttcagttac aaattctcta
     9781 agttcatgta ctaagtcata aattagaggt ttgtctttta agagtttttc tatagcattt
     9841 aattgtatta ttgttgtaga aagagaatgt cctacactat catgtatttc tcttgatatt
     9901 cgatttcttt cttttaaaat tgctaattct tctatagaac ttgcataagt ttccaaatca
     9961 gcattaactt tttttaattc atctttagaa attctaagct tatcataaag attttgactg
    10021 tataattttg ataaattctc attttctata tatatagaaa gtacagttat aattagcaat
    10081 atagagcttg actccagtgc caaatatata tttttatcta aactaataat aagagaagat
    10141 attataacaa aagagaacaa tatgtactta tatttttcct ttattaaaaa tgatatatct
    10201 aatattaaag gaacaaagta aatcgaatta aaagtttttg tataattaca aagtataaaa
    10261 attaatataa gttctaaaaa gtaagaaata agtataaatt tattctcatt tgataaagaa
    10321 aaaaatctaa cttgattatt tattataatt agaaataata ttatcatagt tatgaccgga
    10381 tacaatgtat tttcaacatt tttcaaatag cttacaacta atataaataa agataaatat
    10441 cgtataaaag caactaattt ttctctgttc attaaaggca ctcctccaaa aaaataaact
    10501 tttcctatga aaactagaat aatatcataa aagaataaag tcaatagaag tatttattaa
    10561 tattgatgga aataaaatca atccaaaaac ttgaatagta aaattgtata ctgaccataa
    10621 tttaaaagtg aaaatttaat gtattggagt gaataatgaa taataaagaa aaaggtgatt
    10681 ttggagaaaa agtagcagtt aattatttgc tatcaaaagg agcaaagata ctagaaaaaa
    10741 attacagatt aaagataggg gaaatagata taatagcaaa aatggaagat gaaattatat
    10801 ttgtggaggt gaaatcaagg tctaacataa agtttggcta cccttgtgaa tctgtaagct
    10861 tcaaaaaaag aaaaaagata attggagttg caagttatta tattataaaa aataacttaa
    10921 ataacactcc cataagattt gatgttatag aggtatattt attagaaaaa agaataaatc
    10981 acataatgaa tgctttttaa aaaagataat gtttttggaa agggttaaat atgttaagta
    11041 ttattaattc aagcaactta gtaggaatcg acagcttttt agttaaggtt gaagtagatg
    11101 taagcaatgg aatacctagt tttaatattg ttggtcttcc aggcaaagaa attaaagaag
    11161 caagagaaag agtaaagtca gcaattctta atagtggata taaatttcca agcacgagaa
    11221 tagttgtaaa tttatcacca gcagatataa aaaaagaagg agctttttta gatttatcta
    11281 taagtatagg ccttttaaga gagttaataa aaaaagatga aaattacata agagaaagta
    11341 tgtttatagg agaattatca ttagatggga aaataagaaa agtaagaggt atattgccca
    11401 taattatggg tgcaaaaact cagaacataa aacgtatttt tataccaatt gagaacataa
    11461 aagaaagtct atttgtagat gaaattgata taattcctat taaaagttta aaagaatgtg
    11521 tcgatttttt aaacgaagag ataaaagtcg ataaagtaag gataatgtct tttttggatg
    11581 ataagtcaag aaaagagaac gaagaattag aaaaagataa tagttatata gattgcaaat
    11641 atactaagat taataatgaa gaaagtaaat atgatgaaga ctttaaagat gtaaaaggaa
    11701 attattttgt aaagaggagt gcagaaattg ctgctgctgg aaatcataat atgtttatga
    11761 ttggacctcc aggctcagga aaaactatga ttgcaaaaag agtaaggaca attttaccag
    11821 atataagtgt agaagaaatg atagaagtaa gtaaggtcta tagtatattg ggtatgataa
    11881 atgaaactaa aggaataatt gataaaagac cttttagagc acctcatcat acaactacaa
    11941 agcaatcttt aattggagga ggaatggatg caagacctgg agaaattgct ttagcacata
    12001 gaggtatctt atttttagat gagatagccg aatttgatag aaaaatactt gagactttaa
    12061 gacaacctat agaagatgga tatgtaaata tatccagagt aaagtacagt gcaaaatatc
    12121 cttgtagagt actgttagtt gcagctatga atccatgtcc atgtggttat tatatgtcag
    12181 agacagagtg tagatgtaga agtaacgaaa ttgatagata cataaataaa atatcaggtc
    12241 cattgttaga taggtttgat atttttgtag aagttaattc tataaaatat tcagatttta
    12301 attctttaaa acaagaagaa agctctcaaa aaataaagag aagagtagaa aatgctagaa
    12361 aaatacagat aaatagattt aggaaggata atataaaaaa taatagtgaa attaaagctt
    12421 acaatttatt taaatattgt aaactggaaa aagaagcttc aaaaacggct gagatgatat
    12481 ttaataaata caacctaagc agtagaagtt atacaaaact tttaaaaatg gcaagaacaa
    12541 tagcagattt agaagaaaga gatttgataa attcacagtg tattatagaa gctttttcat
    12601 ttagaaaggc ttattatagt tattttaaat agttttttga ggtggatttt atggaaaaaa
    12661 gagatactta tttatggtta aaatcaattg gtggaataac aacaaaaaca attgaaataa
    12721 tagaaaatga aatagtaaat attgaagata tatttgattt ttctgaaaaa gaaatatata
    12781 atttaaaaaa tataagcttg aatattagaa aaaatatagt aaaatataga ggtcacgctt
    12841 atttagaaaa tataaaagaa ctactttaca aaaaagcgat taaatatatt tgtaaatatg
    12901 ataaagaata tcctgaaaat ttaaagaata tatacaacgc tccaaagtta ttattctaca
    12961 aaggtgacat aggtttagtt aataataatt ttaatatagc tatagtaggt tcaaggaaac
    13021 ctacagccta tggaattaat tgtgcaaaaa caataagttg tcaactatcc caatatggag
    13081 ttaatatagt aagtggatta gctataggaa tagatgcata ctcgcacata ggttgtatga
    13141 gtggaaaatc taaaactata gcagtacttg gttcaggagt agacaatcct cttccaaaac
    13201 aaaatttaca tttatcaaat aaaatattag aaaatggggg attattatta tcagagtata
    13261 atattaactc gacagtagcc ccgtaccatt tttctaatag aaatagaatt atcagtggtt
    13321 taagtgatgg agtagttgtt gtagaagcag caataaaaag tggtgcacta atcacagtag
    13381 attttgctct tgaacatgga aaaaatgttt ttgcaatacc tggtaatata aattctcaaa
    13441 tgagtagagg ttgtcataaa attataaaag aaggtgcaaa attaattgaa aatatagatg
    13501 atattttaaa tgaatataac atatttaata ttattgataa aaaaataaat caaaaatatg
    13561 ataatataag tctaaatgcc aagtctaagc aaataattga agctataaaa agagaaggaa
    13621 acttgcatat agatagtatt tgtgattata ctggtataga aataaagtat gtaaattcaa
    13681 taatcaatga attagtacta aatgagttag tagtagaaat gaataataaa acgtacagtt
    13741 taaatgtata aattaagatt aggtagtggg ggtgtatggt tttatggcca aaacattagt
    13801 catcgtagaa tcgcctgcaa aagctaaaac tatagaaaaa tttttaggga aaagtcatta
    13861 cacagttaaa gcatcagttg gtcatgtcag agatttacct aaaagtaaat taggtgtaga
    13921 tatagaaaat aattttgaac ctcaatatat aaatataaga ggaaaaggcg atgtaataaa
    13981 agaattaaaa aaagaagcta aaaaatctaa acaagtatat ctagcaactg accctgatag
    14041 agaaggtgaa gctatatcat ggcatttagc tcatatacta aatttagatg aatctgagga
    14101 ttgtagaata gagtttaatg agataactaa ggatgcaatt aaaaaagcaa ttaaacatcc
    14161 tagaaatatt gatataaatt tggttgatgc acaacaggca agaagagtgc tagacagact
    14221 tttaggttat caaataagtc ctatattatg gcaaaaggtt agaaaaggtc ttagtgcagg
    14281 tagagtgcaa tctgttacaa caaagttaat ttgtgacaga gaaaaagaaa taaaggcatt
    14341 tattccaaaa gaatattgga caatagatgt tgaggctaag acagtaaaag acaaagatat
    14401 aactttgaaa ttttatggta aaaatgatga aaaaattgaa ttagaaaatg aagaagctgt
    14461 aaatgaaata ctaaaagaaa tggaaggtaa agatttaaag gttgagaaga tagaatctaa
    14521 atcaagacgt aaatcagctc caaaaccatt tacaacaagt atgcttcaac aagaaggagc
    14581 aaataagtta ttttttacta ctaaaaaaac aatgatgata gcacaagaat tatatgaagg
    14641 tatcgacata gaaggtgaag gtactgttgg tcttatatca tatataagaa ctgactctaa
    14701 aagaatatct gatgaagcaa aagaaaaagc taagggctat atcgtaaaca atttaggaga
    14761 aaactactat aaaaacactg gtgataaaaa agaaaaaaag gatactaaaa aggttcaaga
    14821 tgcccatgag gcaataagac caacctcagt tgatagaact cctgagagta taaaagcctc
    14881 attgagcaaa gaccagtaca agttatacaa tttaatttgg agaaggtttg tagctagtca
    14941 aatggaagat tcagtgtttg atatactaaa tgtagaatgt aaaataggcg atattgtatt
    15001 taaggcaact ggttcaaaaa tgaaatttga tggttatacc aaggtatata atttttcaga
    15061 aagagaagac aaaattttac caagtataga aaaaggagat atattaaata tagaaaatat
    15121 attgccagac caacatttta cacaaccacc agcaagatat acagaagcta gtttagtaaa
    15181 aacactagaa gaactaggta taggtagacc aagtacgtat gctccaacaa tagctactat
    15241 actgaataga gagtatgttg aaaagcaagg aacaagtcta tgtccaacag aacttggaat
    15301 aatagttact gatattttgg aaaataattt ccataaattt atagatgtag attttactgc
    15361 tgatatggaa agtaaacttg atgttataga agaaggcaat acagattgga aaaagattgt
    15421 atcagaatca tatgcaccac ttaaagaggc tattgaagaa gctcttgaaa atatagaaaa
    15481 agtaaatatg gatgaagaaa ctgatgagat ttgcgagaac tgtggttcta atatggttat
    15541 caaatatggt agatttggaa agtttatggc ttgtaaaaac tatcccgatt gtaaaacaac
    15601 tagaccaatt atgaataaaa ttggtgttaa atgtccaaaa tgtgaagaag gagatattat
    15661 acttagaaaa tctaaaagag gtaaagcttt ttatgggtgt tctaattatc caaactgtga
    15721 ctttgtagct tggaataagc caacaggaga gttttgtgag aagtgtggtt catatatggt
    15781 tgaaaaagtg actaaatctg aaacaaaaac agtgtgttct aataaagaat gtaataaaga
    15841 gacaaaagag cataatgacg gaaaagagtg aaaattgaaa aaaatcacat aattctcttg
    15901 aaaaaggttc caatctatga taatctttca agtgtaaaca actaatagaa aaataaattt
    15961 tcattaaatg tgaaaataat attagaaaat ataaaaggtt attaaaaggc ctaaatttca
    16021 tgaggagatg attaaatggc aagtgaagtg ttacaaaaaa caaggaaaat aaataaaaca
    16081 ttacaaacaa gtggtggaag cagtgtctct tttgatttac tggccggagc attgggcgac
    16141 gttttaagtt ctaatgttta tgtagtaagt gcaaaaggta aagtactagg tcttcattta
    16201 aatgatgttc aagacagttc agttatagaa gatgagtata ctaagcaaaa gaaattttca
    16261 gatgaatata ctcaaaatgt gttaaaaatt gatgaaacat tagaaaattt aaatggtgag
    16321 aagatattag aaatctttcc tgaagaacat ggaagattac aaaaatatac tacagtagtt
    16381 ccaatattag gaagcggtca aagattagga acattggtac tttcaagata ttcaaattca
    16441 ttcaatgatg atgatttagt aatagctgaa tacagtgcaa ctgttgttgg tcttgaaata
    16501 ttaagagcaa taggtgaaga attagaagaa gaaatgagaa agaaagctgt agttcaaatg
    16561 gcaataggca ctctgtccta ctccgagctt gaagcagttg aacatatttt tgctgaattg
    16621 gatggaaaag aaggtctact tgtagcaagt aagatagctg atagagttgg tataactagg
    16681 tctgtaatag taaatgcact tagaaaattt gagagtgcag gtgtgataga atcaagatca
    16741 ttaggtatga aaggtactca tataagaata cttaatgaca aacttacaga tgaattaaaa
    16801 aaattaaaaa acaatcaata atctatattt tataggttta gattagaaaa ggtatctatt
    16861 tgaaatagat acctttttta gacgaattat taaggtaatg ataagtatat taaaaaggag
    16921 tgagaaaatg cctttagcag ataaaataag accaaaaaca atgaatgatg taataggtca
    16981 aagtcatata ataggtaatg gaaaaatatt gtctaagata ttacaatcta attttttacc
    17041 aaatatgata ttttttggtc ctcctggtgt tggtaaaact acagtagcgg aaataatagc
    17101 agaaagaagc aataaaagct tctataaaat aaatgctact aattcatctt tagaagatat
    17161 aaaaaaggtg atatcagagc ttggaagtat aaataatgta aatggagtcc tattatatat
    17221 agatgaaata caaagtttta ataaaaaaca gcaacaatca atattagaat ttatggaaaa
    17281 tgggagtata actttgattg ctagcactac agaaaatcca tatcattatg tatataaagc
    17341 tcttttaagt aggtctactg tatttgaatt taaaccttta gaaaaacttg atgtagaaaa
    17401 aggactgaaa agagctgttg aagtattaaa tgaagatagc tatatggata ttgagtgtaa
    17461 taatgatgct attgaagata tagcaattct ttctgatgga gatatgagaa gagccttaaa
    17521 tattttggaa gtggtagtct attcaactaa accaaataag gataatataa cttatataga
    17581 ttcagatgta ataagggcat ctacatttaa taaaattata aactatgaca aaaatggtga
    17641 tagtcattat gatattttaa gtgcatttca aaaatctata agaggaagtg acccacaggc
    17701 atctatacac tatctagcaa gacttataaa aggtggggat ttgataagta tatgtaggag
    17761 acttttagta atagctagtg aagatatagg tttagcttat ccaaatgcta ttgtaattgt
    17821 aaaggcatgt gtagactcag ctatgcaact tggatttcca gaagcgaaaa taccattagc
    17881 agaagctact attcttttgg ctacatctcc aaagtctaat tctgcatgta tagcaataat
    17941 gaaagctatg gatgaactgg ataaagagtt tgttaaggat ataccaaata gtataaagga
    18001 tgctcactat tctggttcta aagaaatagg taggggttgt ggatacaaat atcctcataa
    18061 ttttaaaaat cattatgtaa agcaacagta tttaccagat agcataaaag atagtattta
    18121 ttacatacca caagaaaata aaactgagaa aaatataaaa aaatatttag aatatctaaa
    18181 tagtgatttt tagactgaac tttatgtatc gggggtagat attatgatta taaaacttaa
    18241 ctcaacttat cacagtagag ttatgaaata cttaaaaaaa gaacctgagt acaatttgtt
    18301 tataataggg gatattgaaa gatatggata tggaaataat tttttaaata tatgggcaga
    18361 tgtgggtgaa catggtgaaa taaaggcaat attacttaaa tattttgaat ttatgatgtt
    18421 ttattctgat ggagagtatg atgttgaagg tttttataat ctacttcgta atactaatta
    18481 cgaagaaata tctgggaaaa tatgtgctgt agatgcttta gcaaagagat taggacttaa
    18541 taatttaaag gtagttgatt tttgcaaact tcaaactaaa aagtttttga tagataataa
    18601 ttgtaatgca aaggttaaga gaattaggct tggaaatcta aaaaagacag tgaaacttta
    18661 tgacttaata gatgaatttc acagtacaac tttagagaat ttaaaaaatg gactaaggac
    18721 aggtagagga tattgtatag agattaacaa acaggtggtg tcaatggcaa agagtacttc
    18781 agaaaatagg actcatgcaa tgataattgg agtaggaaca catcctaaat atagagctaa
    18841 aggacttgct acaaaatgcc taattaaact atgttcagag ttactgagag aaaacaaaat
    18901 tccttgtttg ttttatgata atgaagaggc tggaaagata tataaaaaac taggatttga
    18961 aaacattgga aaatggggaa tttattcaaa ataaaaaatt aaaattaatc ttgacaaaat
    19021 tagtagggta taataaaatt atcttgaaag taattcctac taaaacagta tgaattagat
    19081 ttctatatag aggtgataat atatgaagtt gtctactaaa ggtagatatg gactaaaagc
    19141 aatgtttgaa ttagcattaa atcaagacaa tggaccagta tcattaaaat ttattgctaa
    19201 gaagcaaaaa atatcagatc agtacttaga acaaatattt tcatctttaa aaaaatcggg
    19261 tctagtaaaa agtgtgagag gtgctcaagg aggttatttg ctttcaaaga atgctgaaga
    19321 cataacagta ggagatatac ttgtagtatt agaaggacca gttgcattat ctgactgtgt
    19381 actagatgaa gatgtatgtg aaaactcaaa catgtgtgta acaaaaatag tttgggaaaa
    19441 gatgaaaaag ggtatagaag atgttataga ttcaattact cttaaagata tgataaatga
    19501 ctataacaaa aataaattag aaaatgatat aacaaatatt aaaaaataga tttggagatg
    19561 aatgtaatgg aaaaaagaag attgtatatg gattattctg caacaacacc tattaaaaaa
    19621 gaagtattgg atgcaatgat gccataccta acagattatt ttggtaatgc atctagtttt
    19681 cacacattcg gaagagaagc aaaagatgct ttggataaag caagagaaca agtagcagcc
    19741 cttataaatg ctgaacctag tgaaatatat tttacagcag gtggttcaga aagtgataac
    19801 tggacactag agggtatagc ttatgctaat aaaaacaaag gtaatcatat aataacttca
    19861 aaaatagaac accatgcaat acttcataca tgtgaatact tagcaaaaca tcatggattt
    19921 gaaataactt atttagatgt tgatagcgaa ggaaaagtag acttaaagca actagaagat
    19981 tcaataaaag atactactat acttataagt ataatgtttg caaataatga aataggaact
    20041 atacagccta ttaaagaaat atccgaaata gctaaaaaac ataagatatt attccacact
    20101 gatgcagtac aagctacagg taatattcca gtagatgtta aagaattagg aatagatttg
    20161 atgagtatgt cttcacataa aatatatgga ccaaaaggtg taggagcttt atacataaga
    20221 aaaggtgtaa gacttcataa ctttgtccat ggtggagcac aagaaaaaag caaaagagct
    20281 ggtacagaaa atatacctgc aatagttgga tatggaaaag cagcagaatt agctaaggaa
    20341 aatatgcaaa atcatgtaga aactttaact cgtcttagaa ataagttaat agatggtgtg
    20401 ttagaaagaa taccttacac aagagtaaat ggtagcttag aaaatagatt gccaggaaat
    20461 gcaaactttg cattccaatt tatagaaggt gaaggaatac ttttattatt agatatgtta
    20521 ggaattgctg gttcaagtgg ttctgcatgt acttctggtt cattagaccc ttcacatgta
    20581 cttcttgcaa taggtttacc acatgaaata gcacatggtt cattaagact tacagttgga
    20641 gattttacaa cagatgatga tatagattat atactagaga acttaccaaa agtaatagaa
    20701 agacttagaa gcatgtcacc actttatgat gatgcgaaga aacaaggttt agtaaaatag
    20761 acataaagat aaagcataaa aaatagacat aaattgagta ggaggaaaag ataatgcaat
    20821 atagtgataa agttatggaa cattttatga atccaagaaa tatgggagaa attgataatg
    20881 caagtggtgt aggtgaagtt ggaaacccta catgtggaga tataatgaag atatttttag
    20941 acatagatgg agatgtaata aaggatgtta agtttaaaac atttggctgt ggttcagcta
    21001 tagcaagttc ttctatggca actgaaatga taaaaggaaa aactataaaa gatgcattag
    21061 aacttacaaa taaagctgtt gcagaagctt tggatggttt accaccagta aagatgcatt
    21121 gttcagtttt agctgaacaa gctgtaaaag cagctcttat agattatgct caaaagaaca
    21181 atatccatat accagaattg gatggatatg ttatagatga tgctcatgac catgatgttg
    21241 aagaagaaga ataaaaataa gtgattgtgt tatgagaagt ttacaatgat taaaaagaag
    21301 tactaatgat ataattagga cataaaaaat agctgttttt aaaatggcta ttttttattg
    21361 cctaaattaa gtattttaac ttgatttaga ggttaattag ttaacaaaat aatccataag
    21421 attcaaataa taaagatgat tattttttta gaaaatagaa caagctatat tttaaataag
    21481 tacaatactt gctctatatg gtataataat aagtaatgca aaagatgagg tgaaatttgt
    21541 ttatgaataa aaaagtaatg ataggtatga gtggaggagt tgatagctct gtagctgcat
    21601 atcttttaaa acaacaagga tatgatgtca ttggtgttac tatgaagttg tggcaagatg
    21661 atgatgttgt tgaaattgaa ggtggttgtt gctctttatc tgctgttgaa gatgctagaa
    21721 gggtagcaaa taaaataggt ataccatttt atgttttaaa ttttagagaa gtgtttaaag
    21781 aaaaagtaat agattatttt atagatgaat atttggaagg aaaaactcct aatccctgta
    21841 tagcttgtaa taaacatata aaatttgatg atttttataa gaaggctaga caaataggtt
    21901 gtgattatgt agctacaggt cactatgcaa agatagaaaa ggatgaaagt acaggaagat
    21961 atttgctaaa aaaatctgtt acagataaaa aagaccaaac ttatgcactt tataatctta
    22021 cacaagagca actagagcat actttattgc caataggtga ctatgaaaaa gatagagtaa
    22081 gagaaattgc taaggaaatg ggtatggcag tacacaataa gcctgatagt caagaaattt
    22141 gttttgttaa agataatgac tatgcaaatt atgtaaaaaa acattctaaa aagcgtattg
    22201 aagaaggttt ttttgtagat actaaaggca atatacttgg aaaacataag ggtatattat
    22261 attatactat aggccaaaga aaagggcttg gaattacttt tggaaaacca atgtttgtaa
    22321 tagacataaa tccaataaat aataccatag ttcttggaga caatgaagat ttatttaaaa
    22381 aagaacttat tgctaaagat gttaacttta tatcaataga tacgttagaa gaacccttaa
    22441 gagttcaagc caaaataaga tattcagcaa aaccatcacc agctactatt catagagtag
    22501 gagaagatac tattaaaata gtttttgatg aagctcaaag agctattact aaaggtcaat
    22561 ctgtagtaat gtatgatgga gatattgtag taggtggagg tataatcgag aaaagtttat
    22621 aaaaacatct aaaaaattaa aaaaataaac aataaagtat attaagagta agtaaagttt
    22681 ataaaataaa tttattgtat atgaaaatat agtattgatt aattttgtaa aatttagtaa
    22741 tataattagt atattaatta aaaaacaaat acagtgataa ggaatagtaa aatatttgat
    22801 gtcttacaga gagagggaaa tgctggaagc ccttagaata tgatatttga agcagccttt
    22861 tagtagcaat cttgaacaat ttatctttta taaagaagat ttaagtagag attgacggta
    22921 gttacgttat agctaaggtt ttccgaagat atcatacttt gtatgataat tagggtggta
    22981 ccgcgattgt cctcgcccct ataaatttat ttatagggac gaggtttttt atttaaacga
    23041 aaaaataaaa tttattagga ggaacatgat atggaaaaga tgggattaaa tgaaataaga
    23101 agtaagtttt tagaattttt tgagtcaaaa ggtcattatg tagcaaatag ttattcttta
    23161 gtaccaaaca atgataagag tttgttactt ataaactcag gtatggcacc tttgaaaaac
    23221 tacttttcag gtgtagaagt acctccaagt gtgagaatgt gtacatctca aaaatgtata
    23281 agaacaggag atatagaaaa tgtaggtata actgcaagac atgctacatt ctttgaaatg
    23341 atgggtaatt tctcatttgg agattacttt aaaagagagt caatcaaatg gggatgggaa
    23401 tttgttacag aatggctaaa tataccagaa gataagatat gggtgactgt atatgaagaa
    23461 gatgatgatt cttatgatat atgggcaaaa gaaatgaatt tcccagaaga aagaatggtt
    23521 agacttggaa aagatgataa tttctgggaa ataggtacag gtccttgtgg tccttgttca
    23581 gaaatatatt ttgatagagg agaagaatat ggatgtgaca atccagactg taaaccaggc
    23641 tgtgattgtg ataggtattt agaattttgg aaccatgtat ttactcaatt tgatagagat
    23701 gaagaaggaa attatagtct attagaaaac aagaatatag atacaggtat gggtcttgaa
    23761 agaatgggat gtattatgca aggcgtagac actatctttg aagttgatac aattaaatct
    23821 atactagaag cagttgagaa gttaacagga gtaaaatatg gagagaatcc aaaaaatgat
    23881 atatcaataa gaataataac tgaccacata agagctgtaa cattcttagt tagtgatgga
    23941 gtgcttccat caaatgaagg aagaggatat gttcttagaa gactccttag acgtgctgct
    24001 cgtcatggta agttattagg agtaaaagaa ttatttttac agaaactaat agatgaagtt
    24061 ataaaagtaa atgataaagc atatccagtt ttagttgaaa aagaaagtta tattaaaaaa
    24121 gtagttggaa tagaagaaga aaaattcaat gaaactatag accaaggaac agaaatattg
    24181 aactcttata tagaagtatt aaaaaatgaa ggaaagactg tcctaagtgg tcaagaagct
    24241 tttaaactat atgatactta tggcttccct atagacttaa ctaaagaaat attagaagaa
    24301 gaacatctat ctgtagatga agaagctttt aatgaagaaa tggaaaagca aaaagaaaga
    24361 gctagaaatg ctagaggaaa tatggatgga gaaagttgga aggaagaccc tctatcaaaa
    24421 ttagaatcta cagttgacag tacatttaat gggtatagtg aaatttatgg tgaaggaact
    24481 attgaagcta tagttaaaga tgatgagcta gttcaaagtg cagaagaagg cgataaggta
    24541 tctatagtac tagataacac tactttctat cctgaaggtg gaggacaagt tggagattgt
    24601 ggattgataa ctaatgaaaa cttagtttta gaagtattaa atactaaaaa aggtgctaat
    24661 aatagtataa aacatatagg tataataaaa tcaggaagaa taagtaatgg ggacaaagta
    24721 aagacactcg tagatagaga aactagaatg tcagctgcaa gaaatcacag tgctacacat
    24781 ttacttcata aggcattaag agaagtatta ggagaacatg ttaatcaagc tggttcttta
    24841 gtaactccag aaagacttag atttgatatt actcactttg aagcgatatc aaatgaagaa
    24901 ttaaaagtaa tagaagaaaa agtaaataat gttattttat catctttaga cataaaatgt
    24961 gatattatga atataaagga agctaaagaa aaaggagcta cagcactatt tggtgaaaaa
    25021 tatggtgatg aggtaagagt agtttctatg ggagattatt ctacagaact ttgtggagga
    25081 actcacttga caaatacttc tcaagtagga atgttcaaaa tattatctga aggtggagta
    25141 gcagcaggtg taagaagaat agaaggaata acaggaaaag ctgtttatga atacctaaaa
    25201 gaaagagatg gaattatctc tgaagtttgt gtaaacttaa aatctaaaga agataattta
    25261 attcaaagaa taagttcttt attagaagaa aataaaaact tatctaaaga attgcatgat
    25321 atgaaagcta agatgagttt acaatcagtt gattctattt ttgattctaa agttgaagta
    25381 aatggagtta atttgataac taataaattt gaaggtatgg atatggatac actaagagaa
    25441 acagcagata atctaagaga taagcttggt tctggtgtag tagtacttgc aaatgtagta
    25501 gatgataaag ttaactttgt agttactgcc actaaagatg tattagataa gggaatacat
    25561 tcaggtaata ttgttagaga agttgcaaaa atagctggag gaaaaggtgg aggaagacct
    25621 aatatggcac aagcaggagc tagtgatgta tctaaggttg accaagcttt aagctatgca
    25681 agtgaggtta ttaagacaca agttaaataa cattcactca aggaggtttt tagtttggaa
    25741 aaagatttag actacactat gaaatttgaa ggaataccag aagataggat gagtgtagga
    25801 gatactattg attttgtata taaagcatta gttgaaaaag gatataaccc tataaatcaa
    25861 attatagggt atctcctttc tggtgattct agctatataa ctagtcataa aaatgcaaga
    25921 gctataatta aaaaatttga aagagatgag atacttgaag aagtaatcac gcactatctg
    25981 aatagaaagt aggtcaaata aatgagaaaa aagattatgt cgttgtttgc aatagtcatt
    26041 atgatttttg tatcaactgc tagctatggt tttgctgaag aaaaaggcaa ggtcatattt
    26101 attgatatga ataggaccaa tcttggaagt atgatgaata ttccaatctt gaaaaatgag
    26161 atagaaaaga gaggctatgt agctctcatg aatataagag gggatcaagg tactgatgat
    26221 agaaggtctt atgcaagtat gggtgcagga acaagagcta gtgtaactac tgaagactat
    26281 atcaattttc aaaaagtaga ccaagatact gctaaagctt ttgaagtcgc aacaggtcaa
    26341 aaagctaaag aaataaatga tttaggcatt aatagatcta taaatgaaaa tcttgagtat
    26401 ggagaatatg gagcaaattt agggtcatta ggaaaaactt tatcagaaaa tggtttaaag
    26461 acatctgtaa ttggaaatgc tgatataatt gaaaataatc aattagttaa aaacagaaac
    26521 ttatgtttag tagctatgga ccaatatgga aggattgatt caggtaatat tgataatatt
    26581 aataagaaag attctaaaat gccatttgga atatctacag attatgataa attactagat
    26641 gaaactaaaa aatcctataa aaatagtgat gctatatttg tagaacttgg agatacatat
    26701 agattagata tgtatagatt aaatctaaat gataatactt atgatacaat gaagaaaaat
    26761 attgtaaaaa atataaataa atatcttgaa caagtatttt ctatggttgg agaaaatgac
    26821 actgtttata tagcaagtgc atttccaagt gacctagatt ataagaataa gagaagactt
    26881 tctccaataa taaaatttag tggagaaggg aaaggtctac tggaatctgc cacaacaaga
    26941 aaggctggaa ttgttgccaa tttagatgtt ggagtagata tactaggtac atttggtctt
    27001 gaaaataaag agatggtagg tagaagttat actttagtaa ataaagagga caatattagc
    27061 tatctaaaat cactttatga aaggatagtg tctatatctt caataaggtc aactattata
    27121 aatggctttg taggcgtaat atctgcttct tgggtaattg ccatgtttgc gattttcttt
    27181 agaaattata tgccacataa agagcgtgta ttcaaagtac ttaaggagtt tataaaatta
    27241 ggcataataa tgccactatc atttatgtta gctcctttga tgaattttaa aactccaatt
    27301 tcaatatctt tgggaatatt tgcgactacg ctaatattat acttgttagg tagaaaatta
    27361 tttaaggaca atgatataaa gcacatggga ttttttgcaa cacttactat tttagtcata
    27421 gttatagatt ctgtatttgg aacatactta atgcaaaata acataatgag ttatgatgct
    27481 gtcataggag ctaggtacta tggtgtagga aatgaatatg aaggtgtaac tatagcaagt
    27541 gcagtatttg gcttagcagt attattacat tataagaagg tatctaaatt acttgttgta
    27601 attttttcat taataatact tataactagt gcatatcctt caatgggtgc aaatgttggt
    27661 ggagctatat cagaatgtgt agcatatttg ttgtttataa tgcttatata tgacattaaa
    27721 atagatttta agaaagctgt attattagct gtttcagctg tagttgtcgt ttttgcattt
    27781 gcagctttag atatactttc aggtagtgaa tctcatttag gtatgtttgt acagagaatt
    27841 ttcctaaatg gaccaggaga gatattacaa acatttggaa gaaaaattca aatgaatatg
    27901 caactagcac agacaagtgt atgggtaaat attttacttg taggaattgg agtaattgca
    27961 gtgcttatat ttaaaccatc tagacacttt agaaagataa tgaataattt tccaatcttg
    28021 tttaaagggt ttattgcatc tatggttggt tgtataatta ctcttttagt taatgattct
    28081 ggaatagttg ctgcatctac agcatctata tatatactta taccactaat aataataagt
    28141 ataaatatga taatatttga aaaaaataac taaaaaaatt tttactgttc atataggatt
    28201 taaataaaaa atgcaatatg attattaatg taaactggat gcttacataa aaaatcatat
    28261 tgcaattttt atgattgatt atgtaaaatt atatgaagca gtaagcctgt gaccttagtt
    28321 atgataggtt cagaatatgt atttaatcta tagaatataa atagataaag gaggaactat
    28381 gttagatgga agaataatgg gtcttgatgt tggtgataaa actattggag ttgctgtgag
    28441 tgatttgatg ggattaactg cacaaggtgt aaaaacaata aaaagagttg gcaagaaaaa
    28501 agatattgaa gagctaaaag caataataaa agaaaaacaa gtaaataaaa ttgtatcagg
    28561 attaccaaaa aatatgaatg gaactttagg tccacaagga gaaaaagtaa tcaagttttg
    28621 tgaattggta aaagcagaaa caggtattga tgtagagttt tgggatgaga ggctttctac
    28681 agtagcggca gagaggtctt tattagaagc agatgttagt agacaaaaaa gaaaaaaggt
    28741 tatagatatg ttggcagcag taataatttt gcaaggatat ttagatttta aaataaattc
    28801 ataaaagaac tataaaattg aatacttatg atatataata taaataataa aaataaaaat
    28861 aaatttgagg tgaatgacat tatggaagaa aatataataa atttaataga cgaaaatggc
    28921 gttgaaagcc aatttgaaat aatattaaca ttagaagcag aaggaaaaga gtatgcaata
    28981 ttaatgcctt tagatgatga agaagctgaa gaagctttaa tctttagaat tgatgaggat
    29041 gaagaaggtg aaatcttaat acctttggaa agtgatgaag agtatgaaac tgttgtagct
    29101 gtgtatactg ctataatgga agaagaaggt ttaaattacg acgaagatga atcaaatgga
    29161 cttaactaga taagtaatta agtttgtata taaaaatcag atatttatta tatttgcttt
    29221 aattaaacct tattaattgt aaaagcattt atagtatata tctgtttttt tgttttttat
    29281 taaaaatacc aaaaaattta tgaattttgg tgaataatat atcttttatg ggtatatatt
    29341 tatattatga gaataaatta aatttattta aatgtcttga caaaaaatga attatcaatt
    29401 acaatattat ttaataaaga ttatcaattg aaaatagtaa gggtgatgtt atggcaaata
    29461 caatggattt attaaaagac aagttaaaag aaactggttt taagattacg ccacaaagaa
    29521 gagcaatagt tgaaatattg cttaaacatg accattcaca tctaagtagt gaggaaatct
    29581 atgatttagt tagggttgac tgtcctgaaa taggcttagc tactgtatat agaacaatgc
    29641 agctattgga tgaaatagga ttaatatcaa aactaaactt agacgatgga tgtataagat
    29701 atgagattag tctacataaa gaagactgtc ataatcatca tcatcttatt tgtaaaaatt
    29761 gtggaaagat aatggaagct aaagaagacc ttttagacaa tatagaaaaa gagatacaat
    29821 cattgtacaa atttaaaata cttgatcatg atgttaaatt ttatggacta tgtgacgagt
    29881 gtaatggagt aagcgattca gaagaataaa cttctattgc ttaatgtcga tggaagaata
    29941 gtatagaact tttatattct atgctattct tccatttttt attataaacc atctataaaa
    30001 tgcaaatata cagttttcaa gatgcttata gttttaatat tgaaaatata attaatccta
    30061 taagtacaaa aatgaatgat ttttctatga aattactaaa tggtcctcca acagttaaaa
    30121 aacctaaaga aattttcttt tcgcttagcg gataaaaaat tggtattcct tgctttgtaa
    30181 ataaatctcc taaaaacata tgacttgcat aaccaatcgt accataaaaa gataaattat
    30241 taatattagt gattaattct atctgtttta gtaaaaaata tactattata gttgcaaata
    30301 tgctatgaga aaaacttctg tgctttaacc agggaaaaat tgacaacatt agacaaaaaa
    30361 ttgtaaaata tatttcaact tctatgatgt ataagcatat agctaatagt ataaatatta
    30421 atgatagaaa aacttttctt agaaatgtgt gggttagttt tgcttcaata attataattg
    30481 caacaaatgt aattattgcg cttaaataaa aattatcatt tatatttatt gaaataaaga
    30541 aaataataat attaacagca tatataaaaa ttctatatat gtatttggat acattgtttt
    30601 ttagaatgaa atttgagacc atagaattag atttatccaa atcgggtagt acagcaaaag
    30661 tagctgaaac taaaatatca actaaagata taggaatttt aaatattaaa gatgtttgga
    30721 tagctgttaa gattcctatt gcacaatgag ttttaccacg cataaatcct cctaaattat
    30781 ccgatattaa atcatataat atttagagga tatcaaaata aaataggttt gtcaaaataa
    30841 tacgttaaat gtattttaaa tatagcttaa aatatgatac gaattatggt acaataagaa
    30901 taactggtag cgagtgcgtg atttgatatt atttatgatt gtagaacgtg ttaaaaaatt
    30961 aaatagacag aaggagatga tgcaattgtt caaaaagaac accaacaaga taaaggtaat
    31021 ggccttgggt ggacttaacg aagttggaaa aaatatgact gttgttgagt ataaagatga
    31081 aataattgtt atagatgctg gacttagttt tccagaggat gaaatgttag gagtagatat
    31141 agttatacca gatataactt atttagtaaa aaatagggat aaaataaagg gtatatttat
    31201 tacacatgga catgaagacc atataggagc tcttccatat atattaaaga aaataaatgt
    31261 acctgtatat ggggcaagac ttagtatagg tcttatacaa gtaaaactta aagaacataa
    31321 aatgaataat gttaagttaa atgttatagg tcctagacaa gttataaagc ttgataatat
    31381 ggaagtagag tttttgaaaa ataaccatag tataccagat gcttactcta ttgcaataca
    31441 cacagaccaa ggtataatat accacacagg agattttaag attgacttga ctcctattga
    31501 tggagatgtt atggatatgc atagaatctg tgagttgagc aaaaaaggag ttcttttaat
    31561 gctggcagat agtactaatg cagaaaaacc aggatttact atgtctgaaa agactgttgg
    31621 ggtaggtctt gacgaattat ttgcaaaagg aaatggcaga agaattatag ttgctacctt
    31681 tgcatccaac atacacagat tacaacaaat aataaatact gctgaaaagt ttaatagaaa
    31741 agttgctata tcaggtcgct caatggtcaa tgtagttgga gttgcaaaag aattaggata
    31801 cctagatatt tctgatgaca tgcttataga tttaaatgat atatgtaagt atgaagatag
    31861 tgaattagtg ataataacaa ctggttcaca aggtgaacct atgtcagctc ttgctagaat
    31921 ggctttttca gagcacaaaa aagtagaaat aaagagtggc gatttagtta taatatctgc
    31981 tcatccaata ccaggaaatg aaaaattaat atcaagagta atcaatttct tatttgaaaa
    32041 aggagcagaa gtagtataca gtgatatagc tgatatacac gtttctggac atgcctgtca
    32101 agaagaatta aaacttatac atgcattagt tagaccaaag ttttttatgc cagctcatgg
    32161 tgaatataga atgttaaaaa gacatgctga aatagctgaa cagcttggta tggataaaga
    32221 aaatattttt gtcatgcaaa caggagatgt tttagaatta gataaaaatt ctgctaaggt
    32281 agcaaaccgt atacaaacag gaaacatatt agttgatggt ctaggagtag gcgatgtagg
    32341 taatatagtt ttaagggata gaaagcattt atcagaagat ggtcttatga tagttgtagt
    32401 tactatttcc aaggatgagg gtaaggtctt agcaggtcca gatataattt ccagaggatt
    32461 cgtatatgta agagagtcag aagatttaat ggatggagca aaggatataa ttaagaatgt
    32521 tctaaatgaa tgtgaagaga aaaatattaa agaatgggct tatttaaaga ataatattaa
    32581 agaaaaccta aaagaatatt tatatcaaaa aactaaacga aatccaatga tacttcctat
    32641 cataatggaa gtataatata aaaaaactat aaatttgaaa attagacctc ttgtaatttt
    32701 taaagtaata tcaaaaatcc aattgatatt actttaaaaa ttacaagagg tctttttaat
    32761 actcattaaa aaaaaaaaaa tattacataa aataccaatt ataacaatct tttattagta
    32821 aaaactactt atatataaat tttactgata ggaggattct tatggatgat gtttcaagac
    32881 aaaatgctat aaaagcttta aaacaaacaa aaatggaaat agcaggagag tatggaatga
    32941 attatgaaga tgcttttgaa ataatagaaa atgcgtctaa taaaggtgtt ttagaaggtt
    33001 actttaaaaa gcttgaaaag aaaaaaaatt taggtcaagg tatatctagg catttagaat
    33061 aaaaaaagtt aaatgtgaga aaataagttt aaataaactt taagaggtga catcgatgaa
    33121 aaaattagct agtactgctt tggctatatt aattgcgctt actcctttaa gcttttcttt
    33181 tgcaaataat aaggaaaatg ctgatgccaa ccaactaaat atatcttcaa aatcagcaat
    33241 tttgatggat gttggtagtg gacaaatttt atatgaaaag gatgctcata aaaagcttcc
    33301 tcctgctagt gtaactaagg taatgactat gctacttata gtagaagctt tggattcagg
    33361 caagattaag cttgatgatg aagttcaagt aagtgaaact gcatctagta tgggtggtag
    33421 tcaaatattc ctagagccag gagaaactca aaaggttgat acattattaa aaggtatagc
    33481 tgttgcttct gcaaatgatg cttgtgttgc tatggctgaa cacttagctg gaactgttga
    33541 aggatttgtt gatagaatga atgctaaagc aaaagagtta aatatgaatg atactcattt
    33601 tgcaaataca aatggacttc cagttgcaaa ccactataca tctgctcatg atatagcttt
    33661 aatgtctaga gaactattaa aacacgaaat gataagtaaa tacttaacta catggatgga
    33721 taaggttgta gtagggaaga aacaagttac agtaggtctt gcaaatacta ataaacttat
    33781 aaagcattat caaggagcaa ctggtgttaa aactggtttt actcaagaag caaaatactg
    33841 tttatcagca tctgcaaaga gaggtaatac tcatctagtt gctgcaactt taggagcaga
    33901 gacttctcca gaaagattta atgatgcctc tagcctttta aactatggat ttgctaatta
    33961 tgaaagtgtt aagttatgta gtaaaggtga taatatagca acacttacat tggataaggc
    34021 tgatgaaaac aaagttaaat tggttgctaa agaagattta aatgctctta ttaaaaaagg
    34081 aagctctaaa gaatttgaga agaaaattga aatagtaaaa aatcctaaga tgccaattaa
    34141 aaagggaact gttttaggaa aaataaagat atgtaaagat aaaaaagtaa taggcgaagt
    34201 ggaattgata aatactaagg atataaataa ggcaagctat ctacaaatgc ttcaaagaat
    34261 aattgataat atgatataaa taattatcag atgaaatata attataatac acaaagatat
    34321 gattataata cacataaaaa atacccttat gtaattattt gccatagggg tatttttatt
    34381 tactatatag aagtatttta taatcttatg atttttatag aaatatagaa aagtttatgt
    34441 atcttaaaat atcatttgat ttaatatcat atatagggtt gtttaacaat tatctaagta
    34501 aaggcatact accagtaagt ttattcactt tctttttatt cccataaatt gctatcccaa
    34561 aatactgtaa ctcatcttct ggaacactag caatcttttg tgtaaattct tcataaagat
    34621 tgcaactttg tgctacatct gaaaaatcta caacagttaa atcgttaaat tccaaagtat
    34681 ataatttttt acgtaaatct tttattattt ctttgtttcc ttttaaaata ggtacaggaa
    34741 tgtcaataat tcctaagtgg ctattacctg ttttgtcaat tacatctggc ccaacagttt
    34801 ctggggcatg ttttcctagt gtaattccca ttatagctgc tgtattggat ataattccca
    34861 ttggtaaatt ttcgtctatt accatgacac attttgaatt tttattttcc atttttattt
    34921 ctccttttta ccttatttaa agttgtttga atcatcattt ataaatatat tttgatactg
    34981 ctttggtgta agaccaataa aattcttaaa aaagtttgta aagtgacttt ggtctacaaa
    35041 tcctgtttgt atcgcagcat ctataggttc tacgcctttt tctaaaagct ttttagcttt
    35101 gtttacccgt atattttcta ggtatctata tggtgtaata ccttttaatt tcgtaaaatt
    35161 acgaagtaga gagtacttat tcatacctgc tatagtgctt aattcgtcaa gtattatatg
    35221 ttcagcataa ttattttcta gataatcaca tactgcttga atttctatat ttgtattttc
    35281 caagttagat tgcaaatttg gctctgtatg ttcttcaatt aattgttcaa ttaggaagaa
    35341 aaaaagctct tcctttttaa aatccaattc ttcttccatg attatatagt gtaattcttg
    35401 tagtagaggt actaactcac tgcgaaatat aacaggttga ttaaattttg gtaaataatt
    35461 tttacctgta atttcaaaga cggttttttt cattatttct ggcttaatat taatacatct
    35521 gtaatcaagt actttatcat ctatttgttc acaagtatga ctatcaaaag ggttaaaaag
    35581 tagcaaatct ccagtacttg tggtatactc tttattttta caagataaat atctttgacc
    35641 tttttctata aaaccaatta cataatgttc atgaaaatgg tttgggaatt tttgcattat
    35701 gcctttaaat ctatatgctt caatttttaa ttccctatca aagcatactg tgcgttcttc
    35761 ttgtctcact taggtaacct cctttcatgt tatacaaagt gtaacacata tttttttata
    35821 cttcttgtat aatattgact aagagacaat aatgtcaatt catgtcaata taatattaca
    35881 cttacagtag gtgtaattat tatattttca caatgaatat gatataataa taaaagttat
    35941 aaaataaaaa gcaaatttta attttatgcc tagaagttaa aattattata atgtaaaata
    36001 attttgatta taagctattt aattgttata ataatattaa aaatttaatt taggagatgt
    36061 acattaatgt taagtatgaa tataggagaa atagtagcaa gtttagttgg tatagctatg
    36121 gcaatatcaa tacatgagtt tggccatgct tattcagctc acttattggg agatgataca
    36181 gctaaagctt atggtagaat gacattaaat cctgtaagac atgttgaccc aataggtctt
    36241 ttggctatgt ttatccttaa gatagggtgg gcaaagccag taccagtaaa tccaaataac
    36301 tttaaaaact ataagatagg aaacctgata gtttcacttg caggcgtttt ttgtaatgtt
    36361 ttgactgcta tactgtgtgt aattatcaat aagtatgtgc atatgtatgc tataaataca
    36421 atagctgaat atgtgttttt atatagtatt ggatttgcag cttttaactt acttccgata
    36481 cctccacttg atggatgggg agttatatct acatttgtac catataaatg gaatgaatat
    36541 ttgtataaat ttgaaagtat gagttatata attttattaa ttgctttatt tactggtatg
    36601 tatagaataa tattaacacc aatatatgca gtgttgctaa aaatagtata tttatttgtt
    36661 taatataata aacagattaa agagggattg atatgaagta taatatacaa ttacaagtct
    36721 atgagggacc attagattta ctttatgatt taataacaaa gcataaaata gatataaagg
    36781 atatatccat aatagatata actaagcagt atctaaatta tttgaaaatg ctagataaaa
    36841 tggatttaga gataactagt gaatttataa ctatggcatc aaaactttta gagataaagt
    36901 ctaaatatct gctttataag caaaaagatg aagaagaaga cccaagaata gaacttatgg
    36961 aaaagttaga agaatataga aagtttaagg tagcatcaca agatataaaa gaaaatataa
    37021 cttatgttaa tgagagattt tatagaaata aagaagagat aattattgat gacaatgtgg
    37081 atttagaaga tatatcaatt gaagcaataa aaaatatact tccatacata tttaaagtta
    37141 aaacatcaca gatagaaaat gctaatgatg agaaactaga taaaatagta aggaagaaaa
    37201 taatatctgt agaagaaaaa atattatata taagagatat tataaaagag aagattgaag
    37261 ttacttttac aaatattata aaatcatatg aaaatgatga aataatagct acttttttat
    37321 ctatattaga gcttataaaa gaaaaagaaa tagtcgtagt acaagatata ttttttgatg
    37381 atattctaat aagaaaaagt tcggagtgtt aaaatgaaaa gagaagatat aaagtatatt
    37441 atagaatctg ttatgtttgc atatggtgag ccaataagta taaaagaatt aaactatata
    37501 ataaataaag aactttcatc aaaagaaata gagattatgt taaatttact tattgaggag
    37561 tacagagaac aaaatagagg tattcaaata atcaagttag agaataagta ccaaatgtgt
    37621 acaaataaag actatgcaga atatataaag aagattattg aaccaaagaa aaagaaaagt
    37681 ttgagccaag ctacattaga aactcttact ataattgcct acaaacaacc aataacaaag
    37741 gtagaaatag aggatataag aggagtaaaa tgtgataagg tattacaaac tttgtttgaa
    37801 aatgaactta taagagaagc tggtagattg aataagatag ggaaaccaat aatttataaa
    37861 acaacagatg aatttttaaa gttgttgaat atagaaagtc ttgaagaatt gccacctata
    37921 gaaaattatc aagaagtggc aacaaatgaa taaaaatata aaatcacaat aatttagtat
    37981 gtaattttaa attttaaaag atttaaaatg ctctaagttg ttgtgttttt ttgtataaat
    38041 ataaaattat aattctctta aaataaatat ggataattaa gtataaatag taattttttg
    38101 atgataatat aaacatggag cttaatgaat tatttaattt taagtattta ataatagctg
    38161 taatttttat tataagtgta actatgttga ttttaatatc tcatataaac atcttaataa
    38221 tagctgatat aaaaaacaaa gatatttgtt taaagcttaa tataaaatac atgtttaatt
    38281 taataaatat aaatagacaa ctttatccag ctgaaaatag taaaaataat gataaaaaag
    38341 aggggatgaa gaataatata gattcaagta tattattagc tgatgacctt ttgagcattt
    38401 atagattatt aaaaaagata aaaatacatg aactttattc aaatattaat tttggaactg
    38461 gaaatattgg cttaacatct tctgtatatg tattgataaa tactttgtat ggaaatttat
    38521 ttaatatgat tgatgcagaa aaaatgtatt taaatgtaaa tccagatttt acaaaagatt
    38581 atgttttagg aaatataagg atacatataa ggccaagaat aaaagcttta tttaatatta
    38641 taataatgat taataaaatt atgaataaaa ataaaggaaa taaggaaggt gatagtaatg
    38701 agagcaacag gttcgataca gagtcttatg gaaacaactc ttgaaacaat taaaggttct
    38761 atagatgcaa atactattat aggagaccct ataaaaacag atactacagt ggttgtacct
    38821 atatcaaagg ttacaattgg ctttggtata ggaggaggag aatactcaaa aggatatgat
    38881 gataaagata gggaaattga attaaaaaat gaaaaatcag atacgaattt tgctggaggt
    38941 agcgcagggg ctatatctgt acaaccagta gcatttgtag tagttgaaag tggagagact
    39001 agaataatga gtttagacag taatatcaat ctagtggata atatattatc tataactcct
    39061 agagtattgg agaaaattca aaatatatca caaagtaata agaatcaaga taaaaacaat
    39121 atgtaagaat aaaatatttt taaatatgta tatagtttta ggtaaagtag tggggttagt
    39181 ataaatccca ctattttgtt gtgtacttta aacatttata tctaataaga ttttagttta
    39241 aaacaattta aatagataat aaagttgata tatagtataa ttataaaaag aaaagaagta
    39301 ttatattata gatatataaa cgcatttgag atataagagg gagttataaa tcattagttt
    39361 tgaggtgaat gttatgagcg ataaagaatt atctattttg ttgttagaaa gtatgaataa
    39421 ttttcataat ttaataaaga ttattaataa cgaaagatat aaaaaagata aggttcttac
    39481 agaaagacag ttctttgcct tagtaaaaat aagaaaacat gataaaatag agcttaaaaa
    39541 tctaagtaga gatttgcatg tatctacttc tagtctgtgt atactactta ataaattggt
    39601 tgagcaagag tatgtatata gggaagaaga tagtagagat agacgaaata ctttttatgg
    39661 aataactaaa aatggagaaa agatattgga taatgaaata ctaaagtttg tatctataat
    39721 aagtgataaa atggattgcc tagatataga taataaagat aaattattta cttctttgga
    39781 agagtctaaa aatataatag aacaattatt ttaaaaagga gaatttatta tgaatataaa
    39841 gtattctaaa gaaatattaa aaagtttaga aaatgctata acagtagtag ctctatttga
    39901 gggagaagat gtttctacga catttgataa aataaatatg ataagcagaa attttaattc
    39961 taaagaaaat agtatagata ctgtaacatt gattgaaaat aacaatttgg taaatgtttg
    40021 tcttgttggt tttggtaaga gagagttatt gaatagagaa aaaattagaa tcataggtgg
    40081 taatttgtgt aaaaaattaa aaaatatatt gaaaaatgaa gcatataaga gtagtgatgt
    40141 taatgtactg aatcttaatt taaatagtga tgaaataggt tcttttgtag aagggatatt
    40201 acttggaaat tataagtttg ataagtataa gacaaaaatt aaggattttg aaagaaaaga
    40261 agttgatact ataactatat ttactgaaaa agaagttgag tgtcaaatag aaaaggctaa
    40321 aatattagct aattcaacta taatagctag aaatctagtt aatgaaccat caaacgtaat
    40381 atatccaaaa acattagcag tagaaacagt taaacttggt gcagagtttg ggtttaatgt
    40441 tgatgtttat gaagaagaaa aaataaaggc attgggaatg gatgcttttt tcgctgtttc
    40501 aagaggctca attaataaac caagattcat agtaatgaga tactttggag ataaagaaag
    40561 tacagatata ttaggtttag taggtaaagg attgacttat gatactggtg gatattcttt
    40621 aaaatcaaat gcttctatgc tagatatgaa gacagatatg gctggtgctg cgagtgttat
    40681 aggtgctatg tgtgctatat ctcaaagtaa attaaagaaa aatgttatag cagtagtggc
    40741 tgcatgtgag aatgctttat caggaggttc atacaaacct ggagatataa ttagttctat
    40801 ggcaaagaaa actattgaag ttttaaatac ggatgcagaa ggtagactta cattagctga
    40861 tgcaatatac tacattataa acaatgaaaa agtaacaaag gtggttgatg tagctacatt
    40921 aactggtgct gctttaacat tgttaggtaa tgttgcaact cctatagtaa caaataatga
    40981 tgatttttat tgtgaattag aaaaagctgc cactttatca ggggaaaggg tatggaagat
    41041 gccaatttat gatgaattta aagatatgat aaaaggagaa gaagcagacc ttaaaaacac
    41101 tggtggtaaa aatgctggat gtataacagc aggagctttt attggtgaat ttgttgggaa
    41161 tactccttgg atacatatgg atatagcggg gacaagtaca tcatcaaaat caattggata
    41221 caaagcaaag ggggctacag gagaacctgt tagaacattg tactatttgg cagaaatcta
    41281 aaaaacaatt ataaaatata atttataaag ccacgtggat atttttgtaa tttaagatta
    41341 tctatgtggc tttatttttt atttaaataa attatttact ctttttcttt ttttcaagta
    41401 taaaagtatc tctattaaat aaaagagcag gtatgtacat aatactagta acaaaaataa
    41461 acgtaaaaat agcagttgtg ctatgactta aaaaaccata atagtaccta gagttggtga
    41521 atgtgtttag taaaaatatg aatgaaaaat aaataaaaca tatagctaag ttatctctaa
    41581 gtgcatatct gttaactcta aattttctaa catcaaccat atatatatct gcataaatta
    41641 tcaagcactt agagaagata aagataaaat atattaagct aggaaattca tagcccaagt
    41701 ttttagaaaa aatgagttct ccaactgaac aaactaaact ccaagaaaaa aatatattaa
    41761 aaagatgata ctgcttaaaa attagtatgg ctatacacag atatatacaa atataattga
    41821 ttccaattgg taaagagttt agagtactat aattacctga agaaataagt aataattgct
    41881 ctagagccat aattattaca agtaatgtac aaattatctt ctcaactgta tagctataag
    41941 gtaaaatatt tttggttagt tttggacaat agtataaaaa taatccaaat ataaagagac
    42001 ttacaaattg ttcactagaa aaaagaaaaa ttttaaacat ataacattct ctcctataat
    42061 aaattt
//
LOCUS       DAEPXW010000028        42016 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.029, whole genome shotgun sequence.
ACCESSION   DAEPXW010000028 DAEPXW010000000
VERSION     DAEPXW010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42016
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.029"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            302..1846
                     /locus_tag="KRM55_001447"
     CDS             302..1846
                     /locus_tag="KRM55_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1593696.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFEFI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDEGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
     gene            2022..2390
                     /locus_tag="KRM55_001448"
     CDS             2022..2390
                     /locus_tag="KRM55_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1593697.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            2392..3117
                     /locus_tag="KRM55_001449"
     CDS             2392..3117
                     /locus_tag="KRM55_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593698.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            3111..3875
                     /locus_tag="KRM55_001450"
     CDS             3111..3875
                     /locus_tag="KRM55_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593699.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            4097..5347
                     /locus_tag="KRM55_001451"
     CDS             4097..5347
                     /locus_tag="KRM55_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1593700.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNVVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            5538..6422
                     /locus_tag="KRM55_001452"
     CDS             5538..6422
                     /locus_tag="KRM55_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH1593701.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            6784..7401
                     /locus_tag="KRM55_001453"
     CDS             6784..7401
                     /locus_tag="KRM55_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH1593702.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTTDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIIKPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            7509..10040
                     /locus_tag="KRM55_001454"
     CDS             7509..10040
                     /locus_tag="KRM55_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1593703.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIRE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            10474..11175
                     /locus_tag="KRM55_001455"
     CDS             10474..11175
                     /locus_tag="KRM55_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH1593704.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            11225..12298
                     /locus_tag="KRM55_001456"
     CDS             11225..12298
                     /locus_tag="KRM55_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1593705.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIV"
     gene            12568..13668
                     /gene="vanG"
                     /locus_tag="KRM55_001457"
     CDS             12568..13668
                     /gene="vanG"
                     /locus_tag="KRM55_001457"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH1593706.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPILHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            13665..14471
                     /locus_tag="KRM55_001458"
     CDS             13665..14471
                     /locus_tag="KRM55_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1593707.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            14489..16627
                     /gene="vanT"
                     /locus_tag="KRM55_001459"
     CDS             14489..16627
                     /gene="vanT"
                     /locus_tag="KRM55_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH1593708.1"
                     /translation="MMRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            16941..17561
                     /locus_tag="KRM55_001460"
     CDS             16941..17561
                     /locus_tag="KRM55_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH1593709.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(17727..18263)
                     /locus_tag="KRM55_001461"
     CDS             complement(17727..18263)
                     /locus_tag="KRM55_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH1593710.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(18376..19050)
                     /locus_tag="KRM55_001462"
     CDS             complement(18376..19050)
                     /locus_tag="KRM55_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH1593711.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            19253..21127
                     /gene="asnB"
                     /locus_tag="KRM55_001463"
     CDS             19253..21127
                     /gene="asnB"
                     /locus_tag="KRM55_001463"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH1593712.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(21219..22655)
                     /locus_tag="KRM55_001464"
     CDS             complement(21219..22655)
                     /locus_tag="KRM55_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH1593713.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVNRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            22984..23562
                     /locus_tag="KRM55_001465"
     CDS             22984..23562
                     /locus_tag="KRM55_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1593714.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            23601..24179
                     /locus_tag="KRM55_001466"
     CDS             23601..24179
                     /locus_tag="KRM55_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1593715.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            24265..24894
                     /locus_tag="KRM55_001467"
     CDS             24265..24894
                     /locus_tag="KRM55_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1593716.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            24884..27643
                     /locus_tag="KRM55_001468"
     CDS             24884..27643
                     /locus_tag="KRM55_001468"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH1593717.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            27730..29292
                     /locus_tag="KRM55_001469"
     CDS             27730..29292
                     /locus_tag="KRM55_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBH1593718.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAIDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            29293..30429
                     /locus_tag="KRM55_001470"
     CDS             29293..30429
                     /locus_tag="KRM55_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH1593719.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            30493..31569
                     /locus_tag="KRM55_001471"
     CDS             30493..31569
                     /locus_tag="KRM55_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBH1593720.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            31547..32785
                     /locus_tag="KRM55_001472"
     CDS             31547..32785
                     /locus_tag="KRM55_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBH1593721.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            32839..33927
                     /locus_tag="KRM55_001473"
     CDS             32839..33927
                     /locus_tag="KRM55_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBH1593722.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            33955..34746
                     /locus_tag="KRM55_001474"
     CDS             33955..34746
                     /locus_tag="KRM55_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBH1593723.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(34861..35415)
                     /locus_tag="KRM55_001475"
     CDS             complement(34861..35415)
                     /locus_tag="KRM55_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1593724.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            35611..36813
                     /locus_tag="KRM55_001476"
     CDS             35611..36813
                     /locus_tag="KRM55_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBH1593725.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            36889..37869
                     /locus_tag="KRM55_001477"
     CDS             36889..37869
                     /locus_tag="KRM55_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBH1593726.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLISVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            38116..39069
                     /locus_tag="KRM55_001478"
     CDS             38116..39069
                     /locus_tag="KRM55_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1593727.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRESIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            39059..40015
                     /locus_tag="KRM55_001479"
     CDS             39059..40015
                     /locus_tag="KRM55_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1593728.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFVIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            40012..40767
                     /locus_tag="KRM55_001480"
     CDS             40012..40767
                     /locus_tag="KRM55_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1593729.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVKKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            40859..41824
                     /locus_tag="KRM55_001481"
     CDS             40859..41824
                     /locus_tag="KRM55_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1593730.1"
                     /translation="MNKKAAIVATVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT        16363 a         4328 c         7234 g        14091 t
ORIGIN      
        1 gaaaagaaaa tattaaaatt ataatataaa aataaaattt ttcagacaat ttaaacaaaa
       61 ataatcacct tttaataaat aattatatgc caaaataatc caatttattt tctattatac
      121 ctatatgaaa tatataaatc aatagttaag acaatgaata tactacattc tataattata
      181 gtagcagaaa attttacaaa attaaagtag atataaacta tccattttac aagaaatgga
      241 aacttttgag atgtacttat ttgctaataa aatagaggtg ttttaatggg aggaaatttt
      301 tatgaggaat ttacaaaaaa aattgatgtt ttttttattt atttgtataa ttttacaaat
      361 tacatacaca acaccagtct attctttatg caaactctat aaaaacaact ccataaataa
      421 ctttgagttt attgtgtcta ataatcagct tattagcaaa catgcaatac aaataatact
      481 tattatggct ataatatgtg taatacttat attctatata atatatgata aattaaattt
      541 taaaattaaa ttgcaaagga tagcatatac agataatctt acaggagcaa atactataga
      601 taaatttgta attgatgcta acaaaatact atgtaaaaat actcaagtaa agtatgcttt
      661 attatatata gatattgata aatttaaata tataaatgat ttatttggat atgaagttgg
      721 gaatgaaatt ttgcgtaatt taacaaagat tattaagagt aatatatttg aagaggaaat
      781 gtttgcaaga atatctgcgg ataattttat tataattatg aaatatatag aagaagaaga
      841 tataacaaag aggttaaaaa ctatatttga agaattagac ttgtttaata ataatcaaga
      901 agaaaaatat aagttagttt taagttgtgg aatctatttt atacttccag aagatagaga
      961 tatcaactca atcatagata gggctaatat acctcataaa atggcaaagg gaggacataa
     1021 aagttcatat gcattttatg ataataagat tcatgaccaa gagataaaag aaaaagagat
     1081 ggaaaataca atgttttcaa gtctagaaaa taaagaattt attatatact tacaacctaa
     1141 gatagaactt aatacaggag agatacaagg ttcagaagca cttgttaggt ggaaacgtcc
     1201 tgataaaggg ctaatacctc caaatgaatt tatcccattt tttgaaagaa acggttttgt
     1261 tataaattta gatttatatg tgcttgaaga agtatgtata taccttagaa aatggattga
     1321 tgaaggaata aatccagtta ctgtttcagt taatgtttca aggatacatt tatattgcaa
     1381 taattttata gaaacataca aaaatataat tgataaatac aatatacctg caaagtatat
     1441 agaacttgaa ttaacggaga gtatcatatt tgataatttt gatattttaa ttgatataat
     1501 gaataattta aaaaaaatag gatttttaat atctatggat gattttggtt cagggtactc
     1561 atcattaaat atgttaaaag aaattcctat ggatatctta aaacttgacc aaaaatttat
     1621 tatggaaact tataatagta aaagaagcaa aataattgtt actaaagtaa tagaaatggc
     1681 aaaagagttg ggtatgaaag tcatatcaga aggagttgag acagaagaac agtttaaact
     1741 tttaaaagaa gtaaagtgtg atatggcaca aggatatttg tttggaaagc caatgccaat
     1801 tgaagaattt gaacatttaa ttgtatctaa cttggtaaga gggtaattaa tctgtaatat
     1861 aaagaattta ataaattgtg ttaaaaatgg actctaatgt agtgttcatt ttttttgtaa
     1921 aattttttat acttttacta aaaagtaatt gacatatact ttgtattatt atattattgt
     1981 attaacaact taatacaata atataataag gaggcatgaa catggaatgg gaacttgata
     2041 ataacaaacc tatatatata caattagtag aacatttaaa gttaaaaata atttcagggg
     2101 aaattaaaat aggatctaaa ttagaaacag tgagagcact agcagaagat gcggaagtta
     2161 atccaaatac aatgcaaaag gctctaacag aacttgaaag acaaggttta gtttatagtc
     2221 agagaactaa aggaagattt gtaacagatg ataaggaaaa aataaaagct atgaaagagg
     2281 aaatagctaa tgtggagata aatacattaa aagtaacctt agaaaagctt ggatatgata
     2341 gagatgaaat gctaaaactt attacagaaa atctgaaagg agaattataa aatggataaa
     2401 aatataagca atgtttctca agatggaata gttgaattta aaggtgtaaa caagagttat
     2461 ggaactaaga atgttttaaa aaatattgat ttaaatatac caaagggaaa aatagtcgga
     2521 ctgttaggac ctaatggaag tggtaaaagt acaatgatta agctaatgaa tggattatta
     2581 cagcctgata atggtgaaat tatgataaat ggaatgaaac catccataga tactaaaaaa
     2641 atagtttcat atttaccaga aagaacttat ttaaatgatt ggatgaaggt atcagattta
     2701 cttaagtttt tctatgattt ttatagtgat tttgatgtta gaagagcaaa tgagatgatt
     2761 aaaagcttag atattgatgt aaatgaaaag ctaaagacaa tgtctaaagg aactaaagaa
     2821 aaagttcaac ttattttagt aatgtcaaga aatgcgagca tatatatatt ggatgaacct
     2881 ataggtggtg ttgacccagc tgcaaggtca tatatactta agactatatt aaaaaattat
     2941 tctgaagata gtactttact gattgctacc cacttaataa gtgaaataga aaacatatgt
     3001 gatgagataa tattcatatc aaaaggagaa atagtgttac aaggagacgt tgaagcaata
     3061 agagaagaaa aaggaaaatc tatagatgca ttatttaggg aggaatttaa atgttaggta
     3121 aattattaaa atatgagtta aaagcaagtg gaagaatatt tataccgtta tatatagcca
     3181 tattgatagt agctgtattt aatggaatat ttatgaatac aaatatactt caggtacagg
     3241 gaataggaat actagtatta acaagtcttt ttatggcatt aggagtttta actattgtag
     3301 ttacaattca aaggtttaga aaaaatcttt tgggggatga aggttattta atgtttactc
     3361 ttcctgttag cactagttca cttatattat ctaaatgtat aacagcactt atatacgctg
     3421 tacttagttt tatagttgca gtattcactt ttggagttct tatgcttttt ggtacttctg
     3481 gaattttact acctgaaatt ttagatttgt ttaacactag ttttaaatgg atttctgaaa
     3541 actttttaga tattttatta ttagtagtag taatgtttat ttcgtattca tcatttattt
     3601 tgttattata tacatcaatc tcaatgggac aattgccaaa attcaataaa catagaaaca
     3661 tagtggcatt tgcttctttt atagctataa atatagtaat atcaattgtt ggagatgcag
     3721 ttggaagcat cttaccaaat gaagatacaa atatggtata tcatctttat cagagtccta
     3781 gttttatgct tgcaatactt ggtagtcttg tagttgcaat agcgttattt ttcgctacaa
     3841 aatttatatt agataaaaaa ttaaatttag aataaatgtt tttatatgga gctatctttt
     3901 gagtaatgtt aaaagatagc tcttattatt tatgtagtta attcatgtat ataatatgaa
     3961 tagtgtttta tttctagtta aatatataca tatgttgtat aatgatattg cgtgtaaaaa
     4021 tttgtaagaa taactataca ctttatataa gttatatcaa gaaaatttaa aaatatatgg
     4081 atttgaggga gaagatatga aaagttatac aaaggctaag tggagtgttt ggggtataat
     4141 tacattttca tttgttttag tattattttt aaggatgtca actgctgttg tttcagacaa
     4201 tttagcaaat gagttaggtt ttaattctat acaaatttca aatatagcat ccttttgcct
     4261 atatgcatat gcatttatgc aaatacctgc aggaattttg attgataaat atggagcaag
     4321 aaaaattagc agtcttggaa taataatggc aagtttaggg tcaattttat ttggtttgat
     4381 tcaaagtata gaattagcat atatttctcg tgtaattgta ggggcaggaa catcagtaat
     4441 attactttgt attttaaaaa ttcaagggag atggtttaat aagtcagaat ttgcttctgc
     4501 aacagctaaa ttttcatttg taggaaattt aggtggagtt cttgctactt ttccacttgt
     4561 gtttttgtct gaacttgttg gttggagaaa ttcattttta ttaatcggta taattggtgt
     4621 tgtaattgga tgttttatgt atattattgt tagagataca ccaaaagagt atggattcaa
     4681 tgtagatact gaaccctatg aaaagtcaga gaaggttaat gttgttgatg gtattaagtc
     4741 tgttataaag aacaaatcaa catggtataa ttcaatgata atgttctctt ttgttggtct
     4801 tacaagtgca tttataagct tgtggggagt aagatacata atggacgttt atggtgtgag
     4861 taagagtttt tctgcgttta tagtatcatt ttttacatat ggatttatat ttggttcaat
     4921 aattatggat tttgtatttg ctaaaataag gtctagcaaa tttaatataa taaaatttgg
     4981 ggcaatgata gatttgttta tatggattgt aattgtagtt gtataccagg taaaaccacc
     5041 aattatagtt ttaccaatat cattctttat tatgggatgt atagttatgt cacatctaca
     5101 ggtttttaat gatgccaagt ataaaaataa agaaatttat tctggactgg caactagtgt
     5161 tattaatact tttgaattta taggaagtgg aattattaat ttgattatag ctatctcttt
     5221 acaagtaaat tcatataata tagttgatgg atataaaaaa ggttttgtag tatttatagt
     5281 actaagtatt ataactatag tatcatctca tataggggta aaaaatgatg attttaaggc
     5341 tatatagtgt tttattaata gtttaattta gtattatatt ttgcatatat ataacaaata
     5401 gtttgcattt tcctaatatg tataattgga atataaatct tgtttactat gtacaaatgg
     5461 tattgtatta tattaaatag aaaataagaa ctttaaacta taatattggt tctaaaatat
     5521 aaggtaagga gttttttatg gatacgacga aaatagatga tataagcaag ttagatttaa
     5581 ataatttaga tattaataag atggatatgg gaggtataat ggaaagtcta ttagaatggg
     5641 ctactacaag cggagtaaaa cttataatag gcatacttat actttctatt ggatttaaaa
     5701 taataaaaaa atttgtaaac catgttatgt tattacttag taaaagagat attgatttaa
     5761 ctttaagaaa gtttttaaag tctcttcttt tgagtgtact taaagttgcc gttataatca
     5821 ttgttctgga atattgggga atgagtttgt ccagttttgc tgctgtgata gcatcagcag
     5881 gggtagcaat aggtttggct ttacaaggta gtctatcaaa ttttgctgga ggatttatta
     5941 tactattgat tagacctttt aaagtaggag attacgtaga agcagcaggc catggaggaa
     6001 cggttgaaca aataggactt ttttatacac aattggttac tccagataat aaacagatac
     6061 ttatacctaa tggttctgta tcaaatgata gtctaataaa ctattcagca aagaatacta
     6121 gacgagttga tttgactttt agtgtagggt atgaagatga tatactacat gttagaagag
     6181 tacttaaaga tattgttaat aatcataaat taataataaa tgaaccagaa ccatttatag
     6241 gagtagtaga acatggagat aatgctatta aatttgcaac tagagtttgg tgcaagacag
     6301 aagattattg gacaatttat cttgatttac tagaagaggt taaagttagg tttgacgaag
     6361 aaggaattac gattccatat cctaaaatgg atttaacggt aaaagaatta aacaaaattt
     6421 aattttttaa tatagtgttt aaatttaaga atatcatata gatatactta taaggtttgt
     6481 aaaaaattaa taagtactgt tattttgtaa gtaaaaatat aaaaaaatgg gagtgtctca
     6541 aaatgaactt tttagttcat gaggcactct ttttgtacga aataaaatat atttttatta
     6601 tttcaacaat gaaaaagatg cttgtttcta ttttgagaca gtataatttt tatgtaactt
     6661 taattttagt aaatataaag ttttaaaatt gataaaatag gaggaatttt taatataaaa
     6721 gggtaaataa agggtttaga gggcataata tagaataaat taatatattt aaggagggtt
     6781 tttatgtgta aaaaaacgta tttattagtg gtaagtatgc ttatagcggg tttattaact
     6841 gcatgtagtg ggagtccaac tacggattca ggacaagcac aagataatac aaaaaaggag
     6901 gcaaatgcat caaataacgc tttaaaagat gaaaaaaata atgaaaattt aatggaacaa
     6961 gattttaaag tgccatacac agatgcaata aacatattta aagataaata taaggatgct
     7021 gatatagtag atttaagtct tgagagagat ttaaataaat ttgtttatac tgtggaaggt
     7081 gtagatgata ataatgaata taagatgaaa attgatgcta atacaaaaga tgtattagaa
     7141 gataaaacag aaaagttgga ttcagaagat ttaaatggag ttgctagaaa agaaaaatta
     7201 gatttaaatg acataattaa acctcaacaa gctatggaaa ttgcattaaa agaacaaaat
     7261 ggaatggtta aagaatggag tttagacaaa gatttagatg ttacttttta taaaataaga
     7321 atagataaag ataaaaatga atatgacata aaagtagatt ctaaaaaggg aactgtattg
     7381 aaggtagaaa aagaagatta gaagatttaa actatcttta aaataatttc ttttttgaat
     7441 aaattttgtt taaaatataa caagcagggt ataaagagac taaataacta ttttaggagg
     7501 agtacggtat gtcattgaaa tcactaaaaa taaaagaaaa tttatattgg gtaggttcac
     7561 ttgaccctga tttaagagta tttgacataa ttatgtatac accttatgga actacttata
     7621 attcatatgt attaaaagga acagaaaaaa cagttttatt tgagacagtt aaagataagc
     7681 attttgacaa ttatattgaa agattaaatg atttaaatat agattttgaa aaaatagact
     7741 atattgtagt aagtcatact gaaccagacc atgcaggaag tgttgaaaag cttttggatt
     7801 tagctaaaaa tgcaaaagta gtagcttcag aaacagcaat taaatatctt aaggaaatcg
     7861 taaacaaaga ctttgaatat gttgcagtta cagatggaga tacattatca attggggaca
     7921 aaactttaga atttttctct gtacctatgc ttcattggcc agataccata tacacatata
     7981 taagagagga taaaactctt gtaacatgtg attcatttgg tagtcactat agtaatgata
     8041 agatagtaaa tacacttgat gaaaatgaag aaaaggatta cttggatgct ttaagatact
     8101 attatgattg tataatgggt ccatttaaac catctatggt aactgctata gaaaagataa
     8161 aagatttaga tatagatact gtatgtccag gtcatggtcc agtattaact gaaaatccta
     8221 gaaaaattat agacctttat tacaactgga gtgtaaatga acaaataaag ttagaaaaag
     8281 aagttacaat ttgttatgtt tctgcacatg gatatacaaa aattatggca gaagctataa
     8341 aagcatatat tgaaaaaaat agcaactata aagtaaattt atttgatgta atagagcata
     8401 agcaagaaga tattttggca aaaatagcag tatcacaagg tgtattattt ggaacaccaa
     8461 caatattagg agatgcgtta aagcctatat gggatatatt aatatcgtta aacccagttc
     8521 ttcatggtgg aaaagttgct tcagtatttg gttcatatgg atggagtgga gaaggtatag
     8581 aaaatgctat ggagagaata agtcagctta gaatgacagc agtaaaacct tttgctgtta
     8641 actttaaacc atcaaatgaa gagattgata aattacattc ttatacaggt aaattcctag
     8701 ataagttaaa ttctactttt ggaagtaaaa agaaaactaa gaaatttaaa tgtgtaattt
     8761 gtaatgaagt ttttgaaggt gatagtgctc ctagtgtatg ccctgtatgt ggagctaagg
     8821 aagaccaatt tatagaagtt gaagaagatg aagttacttt tagaaaagat actgatgaat
     8881 atttcgtaat agtaggaaat ggagcagctg gtttttatgc agcagatgct ataagaaaaa
     8941 gaaataaaac ttgtaagata actatgattt ctaatgaaga tgagttgact tactatagac
     9001 ctgcactttc tgatggtata aatgaagaac ttggttcaga tttctacatg gaagataaag
     9061 attggtatga taaaaataat atagtagtaa tattaggaac gaatgtagat aaattagatg
     9121 aagtgaataa aactattata gtgaatgatg gagctattaa atttgataag cttgtaatag
     9181 ctacaggaag tagaaacttt ataccaccaa ttaagggtca tgatttagaa aatgtgttta
     9241 ctcttagaaa tataaaagat ttatatagtg taaaagaagc actagaaaaa tctaagaaag
     9301 ttgtagtgat tggtggcggt ttattgggac ttgaagctgc atgggaattt agactaaaag
     9361 gattagaagt agtagtagtt gaagccatgg atagcatact atcaaaacaa cttgataaag
     9421 aaggcagtaa aatattagaa caatgtgtaa gagatacagg aatagatgta agattgggtg
     9481 tagcagttga tggtattgaa ggtgatggaa aagctcaaaa agttgtattt aaagatggag
     9541 atagtgtcga ctgtgatatg gtagtatttt caattggtgt aagagcaaac actcaaatgg
     9601 ttcaggatac atctgtaaaa attgacagag gtattgttgt agataagaca ttacagacaa
     9661 atgttaaaga tatatatgct tgtggagatg ttgcacaagt gggaaatatt agtttagcaa
     9721 tatggccatc ttcagtagaa atgggaaaaa tagcaggggc aaatgcaagt ggagataatt
     9781 tgacatttga aagtgaagta tatccagttt cattagatgc aatgaatgta aaagtattta
     9841 gtattggtaa tatacaaaat tttgataaag aaatttcatc aaaagatgaa ggtcaaagaa
     9901 tatataaaaa attatttatg aaagatggtt cattagttgg agctatactt ataaatgatt
     9961 taagctgtac tgttaaattg ataagattaa tatctgaaaa aggtgatttt gaggatatta
    10021 tgaaggctga tatactataa tttaaataca ttaaaataaa aaggagttgt ctcaaaattg
    10081 atttttttct aatcaaattt taaattcaac tccttttttg aatttttata taaaataaca
    10141 tggaaatttt agtaatgtct gtggttacat acataggttt aattgttttt tatatggatt
    10201 gtctctggta taataaattg aattgtgttt gactgataga tatttttatt gaaagttaat
    10261 acctgttatg cgataataag gacgtgttag gggagttttt ataataacaa ttaatctcag
    10321 tttttgtgtt ccaatagtag catcaacaca ttctgatgta gtagttcttt tcttataaaa
    10381 attagttaca aatatgcttg taattatttg atatgtaaat ttaccaatat tataaatgat
    10441 gacctcgata ataaggagag tgaaaaataa tctatgaacg aaaatatttt gattgtggat
    10501 gatgaaaaag aaatagcaga tttaattgaa gtatatttaa aaaatgaagg ttttacagta
    10561 tacaagtttt atacaggtaa ggaagctcta gaatgtattg aatctaaaaa tttggatatg
    10621 gctattttag atattatgct tcctgatatt gatggatttc atatttgcca gaaaattcga
    10681 gaaaaatact attatcctat cattatgtta acagctaaaa ttgaagatat agacaagata
    10741 atgggtttaa ccataggtgc tgatgattat ataacaaagc catttaaccc tttggaagtt
    10801 gttgcaagag taaagacaca attaagaaga tatatgcgat ataataattc ttatgaacaa
    10861 cagtcgataa ttgttaatga gtatgatatt aaaggattga ttatcaataa agaaacacat
    10921 aaatgtagtt tatttgggaa agaagtagca ttaacaccga ttgaattttc tattctttgg
    10981 tatttatgtg aacatcaagg aaaagtggtt ccttctgaag aattgtttga agctgtatgg
    11041 ggagaaaaat atcttgataa taataacaca gttatggctc atatagggcg attacgtgaa
    11101 aaaattcatg aaccttctaa aaacccgaaa tttataaaaa ctgtatgggg agtaggttat
    11161 acaattgaaa agtaaaaata ttaaagtcaa tcctgacttt actcaagtga gaaataaaat
    11221 ttttatgaga acagctttaa tggcatttat agccattatt ttcatatgga ttttatattc
    11281 ttttatattg tatggtaagt tttctatctg gatagtatca ttctttgaaa atgcttttcg
    11341 tatggaatat aaagctgcat tgaatttata tcagcagatt ttccgtaata gcatggagct
    11401 cttcatgata ctagctatgg tgattgtgtt ttttataata ttccgtgttt atttaaattg
    11461 gtttacaaaa tattttagtg aaataaatca aggtattgac tctcttatca aagaagatgt
    11521 tggagaagtg gctttatctc cagagttatt ggcaatagaa aagaaaataa actcaattaa
    11581 acatatactt gaacaacgta aatttgagac acaaatggca gaacaacgta agaatgaact
    11641 tattgtttat cttgcacatg atttaaaaac accacttaca tcagttatag ggtatctgac
    11701 actacttcga gatgaaagtc agatttctga agaactgcga aaaaaatatt tatctatttc
    11761 gttggataag gcagagcgtc ttgaagattt aattaatgaa ttctttgaaa ttacaaggtt
    11821 taatttatca aatatatcac ttgaatacag tacagtaagc ttaactcgta tgcttgaaca
    11881 actaacatat gagtttaaac ctactttgat gagtaagaat ttaaaatata cactgaatgt
    11941 tacaccaaat atgatgataa ggtgtgatgt taataaaatg caacgtgtat ttgataactt
    12001 attacgaaat gctgtttatt atagttttga agatactact attgaaataa cagctgtaca
    12061 ggaggatgat tatataaagc ttaaatttat gaatcatagc aatacgattc cagaggaaaa
    12121 acttgagcgt atttttgaac aattttacag gttggataca tctcgtaatt caaacagtgg
    12181 tagagctggg ttgggacttg ctatagctaa agaaatagtg gagcttcata acgggacaat
    12241 aacagctcat agcgagaaca atataattac ctttaaggtt attattccga ttgtatgaaa
    12301 tttgtaagaa tttaagtata aaaaaatagg aaattcttta ggataaataa ataaagagca
    12361 ctcttgttat tgatataatt actgtatcaa aacaagagtg cttttatttt gatacagtaa
    12421 ttatatcaat agaaaaatgt gaaaatatat tatgtggaac agatgcaatt gtaagtgaag
    12481 gttgattgga tttgaaatag aaaaagtatt ttaacatgtt tctgtagatt gtataaaaat
    12541 aaataaatca acaaaggaga atcaaagatg aataataaaa aaattgcagt tatatttggt
    12601 ggaaactcaa cagaatatga tgtatcatta caatcagctt ttgcagtact tgagaatttg
    12661 aatacggaaa aatatgatat tataccaatt ggaattacaa gggagggtaa ttggtatcat
    12721 tatattggag attataataa tatccagaat aacacttggt ttgaaaggga tactgatata
    12781 attccagtta ttgtttcgca gaaccgtgtc aaaaatggta ttattgaatt tttaattcct
    12841 gatgctgttt ctcagaatca tattccaaat agtgctattg aatcatgtga aaatgatatt
    12901 aaatacacta aacttgattt tgtatttcct atattgcatg gaaaaaatgg agaagatgga
    12961 acagtgcagg ggttatttga attggcaggt atacaggtta ttggatgtgg tactctttct
    13021 tcagcattat gtatggacaa agacaaatca cataaacttg ttcattcaga aggtattaaa
    13081 gtaccaaaat caatattact aaaatactca gataaattta atgtggctga actgtcaaaa
    13141 gacttaactt atccattatt tataaaacct gtgcgtgcag gttcatcatt tggtattagt
    13201 aaaatttata aaaaagaaga gttacaagta gcagtagact tggcttttga acatgataat
    13261 gaagtaataa ttgaggaaaa tattgatggt tttgaggtag ggtgtgcagt tttaggaaac
    13321 gatgacttac ttgttggaag agtagatgaa atagaattgt caaaaggatt ttttgattat
    13381 acagaaaaat atacattgaa aagttcaaaa attcatatgc cagctagaat tgatttggat
    13441 tgtgagaaaa gaatacaaga gacagcaaaa attatttata gaactcttgg atgttctgga
    13501 tttgctagag tggatatgtt tttaactcca tctggtgaaa ttatttttaa tgaagtcaat
    13561 acaattcctg gctttacttc tcatagtcgt tatccaaata tgatgaaagg tattggattg
    13621 tcttttgaag aaatattgga caagataatt gaggtgtaca taaaatgatg aataatattt
    13681 tattagataa aaataaagaa gataaaatga caaatactat cttattgact aaagataaag
    13741 tttatgatgg gaatctaatt ctagtaaatg cttttttacc agttaaaaca tctgaagata
    13801 tagatttaat tcctgtagat acaaggtttc caagtattct tatgaaacgt gaagctacaa
    13861 acattttaca aaatatttta aaaagtatat gtggaataaa tgaaatagta cctgtaagtg
    13921 gatatcgtac tgcagaagaa caacaagata tatattcaag ttctctgcgt gacaatggaa
    13981 aagactttac taaaaagttt gtagcacttc caaatcacag tgaacatcag acagggcttg
    14041 ctattgattt agggttaaag aaagaagtta tagattttat ctgccctgaa tttccttata
    14101 atggtatttg taatgagttt cgtaaggcag cactacatta tggttttata gagcgttatc
    14161 agtgtaaaaa agaagaaata acaggaatat ctcaagaacc atggcatttt cgttatgtgg
    14221 gatatccgca ttctgagatt atcaataaaa tgaatctcgc tcttgaagaa tatatagaat
    14281 atattaagag attttcgtat acaaattgtt taaaaataga agataaagaa aaaattatag
    14341 aaatctttta tgtgcctatt catactaaag aagaagtgag aatctctata cctgaacaat
    14401 gtgtatatca aatatcgggt aacaataagg atggttttat tgtgacattt tggagaaata
    14461 gaaaggacta agaaatggag gaacaagaat gatgaggaat aaatcttatg cagggcttga
    14521 ttattttagg attatagctg cattacttat aattgcaatt catacatctc cattattatc
    14581 atatagtaaa atggctgact ttgtgttaac tagtataatt gctcgtattg ctgtgccatt
    14641 cttttttatg ctatcaggct tttttctaat ttcaacatat aattataatt gtaataaact
    14701 gaaatctttt ctaaaaaatg tattatttat ttacgggata gctattgtaa tttatattcc
    14761 cttaaatatt tacactggat atttttccat gaataattta gtgcccaata ttattaagga
    14821 cattgtattt gatgggactt tatatcattt atggtatctt cctgcatcaa ttattggtgc
    14881 aagtattgca tactttcttg taaaaaaact aggtttaaag tactcactag taatcactat
    14941 tgttatttat gtaattggta tgtttggtga tagttattat ggttttttag aaaaaatacc
    15001 actattaaag aatttatatg ggtatatttt tgaagtatca gattatacac gaaatggtat
    15061 attttttgca cctgtatttt tcatacttgg tggaataata tctaataaat ctaattatat
    15121 gtcaactaaa aatagcttga ttggatttct tatatcattc ttacttatgt tatgtgaggg
    15181 aatgttttta cataaactag gggtacagcg tcatgatagc atgtatatta tgttattgcc
    15241 atgtatgtat ttcttattta cagccttaac atttttgaaa ggttctcgag ctaggttatt
    15301 gcgaacatca tcattaatta tttatattat acatcctatg atgattgttg ttattcgtat
    15361 gttttctaaa atattcggaa tacaaactgt cttggttgac aatagcctta ttcattatat
    15421 agtggtaagt atagcatctt ttatagcttc tataattatt atattgattc ttaaacctct
    15481 aaaaaaagac ttgaaaggag aacataaggt aaataccaat agagcttgga ttgaaattga
    15541 tttaaataat ttggaacata atgtaaagat gatacaaaaa gctatgccag aagattgtga
    15601 attgatggca gttgtaaaag ctaatgccta tggtcatagt gcttttgaag tagcgacttg
    15661 tgcaaaccaa ataggtgtaa aagcatttgc agtagcaaca atagatgagg ggattgattt
    15721 acgtcgatat ggaatactag gagaaatatt gattcttgga tatactaacc caataagggc
    15781 aaaggaactt cataaataca atcttacaca gagtgttatt gaccttaatc atgctatctc
    15841 tttaaacaaa cagaaataca acataaaatc acacattaaa attgatacag gtatgcacag
    15901 actgggtttt gatgttaatg atgtgaggtc aattttaaag gcatttaaat taaaatactt
    15961 agatatatgt ggcatattta cacacttgtg tgtttcagat agtctgaaag atgaagatgt
    16021 agactttaca aataaacaaa ttgaatgttt ttataagtta attgattttc tgttaaaaaa
    16081 aggtataaaa attcctaaag tacatattca aagtagttat ggttttttta attatcccaa
    16141 tcttaagtgt aattatgtaa gaattggaat tgcattatac gggatattaa gttctccaaa
    16201 tgatacgact aaattgcaac ttgatttacg acctgtttta tccttaaaat cacaagtaat
    16261 tcttattaga aaaatacaaa aagatgatag ttttggatat ggaagagtct ttattgcaag
    16321 cagagatagc gtaattgcta tattatctat tggctatgcc gatggtatac ctagaaattt
    16381 atcctgtgga aaaagttacg taataataaa tggttgtaga gcagcaatag tgggtcgaat
    16441 ttgcatggac caacttgctg ttgatattac agatatacct aatgtagaag ttggtaatac
    16501 ggcaataata ataggaagag ataatttatc tgaattatct gcttctgaag ttgcaaataa
    16561 ctcatgtagt atatcgaatg aattattgag cagagtagga agaaggttaa atgttataaa
    16621 gaagtaactc aattaaatag taatatttgt tgtactgtgt aatttatttt actctgacta
    16681 gacattttta gtaatattat gtctaatata tattttttat aacttacatg acaatttaag
    16741 ttataaaaag gtgatgtttc agatttttat tttgaaacat cacctttttt gttataatat
    16801 ataataaaat aattatacct taactgtaaa cttatataga ttatttactt tttaatatta
    16861 gattcatttt ttgagattgg tatataataa acatatagag tatataataa tagttaaagt
    16921 taaaaaaggg gaaaagcaat atgcagtata tacaagaact acttgatttg actcaaaatt
    16981 attgggtgtt agccacaata atcggcttat taagtgcatt tatagaaagc tttataccag
    17041 ccttaccact tgttgctata gttacagcaa atgctgcaat acaaggatta tttattggat
    17101 gtttgttatc atggattggc tcaggacttg ggacaacttc attattctta ttaataagca
    17161 gatttaatga tagtaagctt tttaataagt tgagaaatag taaaactgaa aaagcaataa
    17221 gttggatgga taaacaggga tttaagttat tatttatagc gtatgcctgt ccatttatgc
    17281 ccggttgttt agttactatc gcatcagctt ttggtaaaaa agatttaaaa gattttgtgc
    17341 cagcaatgtt ggcaggaaaa tttgtaatgt ttatagttat aagttacgtg gcaagtgata
    17401 tagaaggttt tataacaagt cctttaaaga tagcatcatt tatattattg gtgtttttgt
    17461 catggaagat tggaaataga gtaaataaaa atcttgaaaa tcataattat gatttccatc
    17521 ataaaaaaca tcacaatgat aaagatgata aaatgattta gcttgtacga aataaaacgt
    17581 atcttaaaat gatttagtac taaattattt taagatacgt tttatttttt gtattaaggt
    17641 acaaaatttt tagttctttt gtaaactaaa atatataaaa cttatttata cttagttcaa
    17701 aatattgtta tttatttttt ctacaactat aataaaatat aaaattgata tccaatcaaa
    17761 aaaataacta tgaaatttaa tagcttagat atgaattttt ctgtttttga gttagttttt
    17821 ataggtagta aagaaatgtt tatggtaatg ggataaaaca attcaatacc ttctttagta
    17881 ataaggtcaa gacacaagtg agatagatat cctattataa acccactgga caaacatgag
    17941 aaaactatat tattgttagt gaagattgtc agagatttaa aaaaactata aataagtaat
    18001 aaggcaatta gactgtgagt aaaccctcta tgtctaaacc tacttccaaa taatttgtat
    18061 attaacataa attttttact tatgtaagaa cctctcatat ctatatctgg aaataaagaa
    18121 cctaaatatg caaaataaat ataaattata attaatacta ttttatatgc aatatcgtat
    18181 ttaactaggt atagattgtt tataaagggg agtatcaaaa gtgcgaatat ataacctccc
    18241 ctttcatgtg tttcttttat catataaaaa tcctcctgaa tcgtcactat aaacattata
    18301 ttggtaaatt tagactatct tttattatat tatatagcaa acataagttt ttttcaaaag
    18361 gattttaata tttaattaat cttgagattt taaatttttg taattttcta aagcaccatt
    18421 ccaatttact acattaaacc agttgtcaat gtattcattt cttctatttt gatattttaa
    18481 atagtaagca tgctcccaaa catcaagtcc tattatagga gttaggtttt tacttacagg
    18541 gctatcctga tttggagtag tcataataga taatttgcca tctttagtag ctacaagcca
    18601 agcccaacca gaaccaaaga catctaaagc agatttttgg aactcttgct taaatttttc
    18661 aaaagaacca aagtctctat caatagcttc ttttaaagat tcagaaggta tggttttttc
    18721 tggcgtcatt atatcaaaaa agaatttatg attataagct ccacctgcat tatttcttac
    18781 agttgtagca atatctttag gtaaagaatc taaattttgc aataattcac ataaagaata
    18841 attataaagc tcaggatatt tttcaagagc agcatttaat ttatcaacat aagcttgata
    18901 atgcttatca tgatgcagtt tcattgtttc tttatctata taaggttcaa gtgcatcata
    18961 tgcataaggt aatggtttaa ccttaaattt gttattttca ggtgtaaaag caaatgaagt
    19021 tatgcactgt gagattataa ataaagacat aataactggt attaatattt ttttcttcat
    19081 aaaaatcacc tcctaatata gtatttctag aaataaaaaa aatatgaaat attaacagat
    19141 aatttataag aatttaatag caatttcatt ttaaattgaa taagttttaa agccaaagac
    19201 aaaactatga aatatagaat aagactaaag gacagaaagg aattttgatt atatggacgg
    19261 caatatttca atttattata aaggtgatat atctaaaaaa gaagatatta aatttaaaat
    19321 aaaagaatct gtaaataata caagactttc tagtagaata gagtataagg atgaggaaaa
    19381 aacttttgat tttgaaagat ttaatgtaat tgatgctatt tatggaaata aaccatttga
    19441 aaaagatgga aaagttattg tttttaatgg aaatatatat aactatcatg aaataaaaga
    19501 agaattaatt aaaaaaggac acaattttac tacaaatgat gatattgaag tcttattggc
    19561 atcttatata gaatttggta agaattgtgt acataagatt aaaggaatgt tcaactttat
    19621 aatctatgat agagaaaatg aaagtatatt tggagcaaga gatttatttg ggataaaacc
    19681 actttattat ataaataagg aaaatgcaat aattttttcc tcagagtata agtttttact
    19741 tgaatatatg aaaaatttaa atataaatga aagaagctta caaagttatt tttcatttca
    19801 atatgtactt cctgaagata ctatgataca aggaataagg ctgataccag caggtcacta
    19861 ttttagggta gaaaatggta tactatcttt aaagagatat aataaacttg agtttagaag
    19921 tagtacaaaa tttttttata ctaaaaatca cttaggcaat agagatgtga acgaggatga
    19981 tataagaaat atagtagtag attcaatagt aactcatatg gaagaggaga aagaaattgg
    20041 aacatttttg tctggtggaa tagattcatc tattataact actgtggctt cacaaattaa
    20101 tccaaatata aaatcttttt ctgcaggctt tagtgtcaaa ggatatagtg aattagaagt
    20161 agcaaagaaa acagctgata agttaggtat agaaaatatc cagattaata taacacaaga
    20221 tgaatatata aaatcattac cgaatgtaat ttattctttg gatgacccta tagcagaccc
    20281 ttcagaagta ggtctttatt tcttaattaa agaggcaggt aaacatgtta aagtagcatt
    20341 gtctggagaa ggagcagatg aattatttgg aggatataat atatataaag agtatagtac
    20401 tatgaaatca gttgtcaatt cacctactta tattaaaagt atattaggaa gagtttcaga
    20461 acttatgcca aacataaaag gaagaaatta tctttataga gctacaacac cattagaaaa
    20521 aagatatata ggaaatgcaa aagtttttga aaacagcgaa gtaaaaagat tcttttttaa
    20581 gtataaggaa aagaatatat atgaatacct gttgtctaat ttgtatagag atgcacaaaa
    20641 aaataattac gattatataa gtaaaatgca acatatagat gtgaatacat ggcttcaagg
    20701 cgatatactt caaaaaatta gcaaactttc tacagctgag caggttgaac ttagagtacc
    20761 atttttatat aaagatgtat ttgatgtagc aaaaaattta agaatggagc aaaaaataaa
    20821 taagaataat acaaaagttt tacttagaga ggcgtttaga gaaatagtcc cagaacatgt
    20881 tgttcaaagg aaaaaattag gatttccaac tccaataaga gtttggttaa aagattctct
    20941 aggggatatt gtaaaggaaa ctatttataa ttcaaatgta gatgaattta tagataaaaa
    21001 atatgcaata aaacttttag atacgcatct taaaggtcat agagataatt cgagaaaaat
    21061 atggactata tttacatttt gtctatggca tcaattattt attgagcata aaaatgtcga
    21121 gtattaatac tgttttcaat attaatcaga gggcaaaagc atgcaatgtt ttcaccctcc
    21181 tgattattat ggaataggat aagtagaatt ttgattgatt agtttactat ctcaataaaa
    21241 ttattggcaa atattttgac aagactactt tcaacagcta aatttaagtt ttgtccatca
    21301 tcatatccag cggaaatcaa tcctagcaag tttccaaaca tatccaaaag agctcctcct
    21361 gaactaccac tagagattgg agctgtaaat tgtatcattt gaaccgtttc aaaatcacga
    21421 aaagctgaga taattccatc tgaaactgta ttaaaaagac ctaaagggct tccaattgca
    21481 actatttttt gacctctcac aggtttttta ctgactttaa caggtattgg cttgcatttt
    21541 ctattaacct ttatcacagc taaatcataa tctgaatggt attttataat ttggtaagat
    21601 gtataaactt tatcatcatt ttcaaatcta actaaaaatg aatacccatc attgactaca
    21661 tgaagattcg taagtatata accttcatta tttattacta ctccagaacc gctcttaaac
    21721 ggtttatttt cgttattgca cacaacaatc ataacaacag aagctgataa ctttgcaagg
    21781 tcttcataag aaagttctac ttcctcatct tgtacaattt ttttagatgt tagatttgtg
    21841 ttattaagtg tatttttaga gttaggttta ttcgtagtag gagaagtctt attggtattt
    21901 tcactgtaat ttatatttgt aatatgcctt tcaaaaggta tttctaatat atttggagtc
    21961 ttcctagaaa gttcaaatag agtagaaaat tttgaacatt caggatataa atcaagaata
    22021 tctttatttg gatttatata taaaatatca cacccaagtt gtgataaaaa atataagaaa
    22081 aaaagttctt gccttttaat atttccaaag tatactatct ttggtgaaat agtagtcttc
    22141 accttgttat aaaataattt aggtagaaaa tagtctatcc aacacaaaag tttaactgca
    22201 aagtttttga tgatagagga tgtacaattt ggcatacttg tggaaaataa atctaaagta
    22261 tttttaaatg caatcttttt agtccaattt aaagtgtcat tttctatttt acatggaaag
    22321 tcgatattat ataaatccca actgttaaac ttagaactat cataaatatt aaaaatttta
    22381 agcatcttat ctgtttgttc tttgtcaaaa tttattttta gattgtttaa tctaatatag
    22441 ggaattgtag gattattaaa aaaataagta tctatatttt taattttttc tatgtattta
    22501 tcaattgaat catcaacacc tatatatctt gtaaagtaga cttctttaat atatgaagaa
    22561 ctcttatttt tataggtagt atcagatata aattcaatta gaggttcagt agactttttt
    22621 attgaaatct ttaatggttt aatagtacaa atcatatttt ttctcctata ataagatgat
    22681 ataatctatt ataaaacaac ttaaaacaat atagtacaat aattttgtag tttcaaaata
    22741 aaatatgtac ttgtttatat aaatgatata taattacata ttaaacatag cttttatgca
    22801 tttaataaag tatgtaaaat ctatgtaaaa agtaagaaat ataaacattt ttttaattat
    22861 attttaaaaa tatcaagcaa gttttcttca caaatgaata aaaaatgtta taatatgatt
    22921 aaagaaaaag ataaataatt agcaagattt gtttagctaa aattaacaag ggagcgataa
    22981 attatgggta taacattatc aaaaggccaa aaggttgatt taactaaagg aaatccaggt
    23041 cttaaaaata ttttagtagg tttaggatgg gatactaaca agtatgatgg tggatttgac
    23101 tttgatttag atacagcagc atttttaaca ggagcaagtg gaagtgttac taatgatgga
    23161 gattttgtat tttacaacaa tttaaaacat acatctggag cagttgagca tctaggagat
    23221 aacagaactg gcgaaggtga tggagatgat gaacaaatag ttgttgattt atctaagatt
    23281 cctggagaaa taagcaagat ttcttttact gttacaattc atgatgcaac agaaagaaga
    23341 caaaattttg gacaagtaag taattcttat ataagaatag tagataaaga cacaaatgaa
    23401 gagttaataa agtatgaatt aggagaagat tttagtatag aaacagctat agtagtagct
    23461 gaaatatata agcacaatgg agaatggaag tttaatgcac taggttctgg ctttgaaggt
    23521 ggtcttgctg cattatgtgg aaactttgga ataaacttat aatttcaact ataacaataa
    23581 actaaagggg gatattttcc atggctatag tattaaaaaa aggacaaaaa atcgatttaa
    23641 ctaagggaaa tccaggtctt aaaaatataa aacttggact aggatgggat acaaattcat
    23701 ttgatagtgg ctatgattat gatttagatg taagtgtttt catggttgga gaatctcaaa
    23761 gagttgaaaa agatgaagat tttatattct acaataactt aaaacatcca tctggagcag
    23821 ttgaacactt aggtgataat agaactggtg aaggtgatgg agatgatgag gaaatattag
    23881 tgaatttaga gacaatgcca aagcatatac aaaagatagc tgtaacagtt acaatatatg
    23941 aggctgctga aagaagacaa aattttggac aagtaagcaa ctcatatata agagtattaa
    24001 attctgaaaa tgatgaagaa atattaagat atgacttagg tgaagaattt agtatagaaa
    24061 ctgcaattac agtatgtgag atatataagt ataatggaga atggaagttt agtgcagttg
    24121 gagcaggatt tgaaggtggc ttagaagcac tttgtagaaa ctatggctta aatgtttaat
    24181 ttaagcaata taatatatta aatataaata acctatacaa ataatgtata ggttatatta
    24241 tataaaattt tgtggaggtt tagtatgtcg attaatttat caaaaggtga taaaatagat
    24301 ttaaaaaaat ctaacccagg actgagtaac atacttgtag gtctaggatg ggaccctgtg
    24361 caacaatctg gaggaggttt ttttaaatcg ttatttggtg gaggacaagc tgatatagat
    24421 tgtgatgcat ctgtatttat gcttaatcaa gaaggtaaat taagtggaat aaaagattta
    24481 atttattttg gaaatctaaa aagtgcctgt aaatcagttt tgcatacagg agacaatcta
    24541 actggtgagg gtacaggtga tgatgaacaa atcctagtta atttggataa agttccatca
    24601 aatattcata aattattgtt tgtagtaaat atatacaatt gtgtagatag aaaacaacac
    24661 tttggaatga tagaaaatgc ctatataaga gttgaagacc aaggtaataa gaaagagata
    24721 gcaaaataca atctatctga taattattct gaaaaaacta ctcttatagt aggagctata
    24781 tatagaaaag atggaagttg gcaatttaaa gcaattggtg aaggaacaaa agatgcgggt
    24841 cttaaagaag taatgcaaaa tttagacagg attgagtgtg catatggaat ttaataatga
    24901 tatcaaatat tataatgtag ataaagaaga agttacaaaa gacttatctg ttaatcctga
    24961 aaaaggttta tcagaatcag aagtcaagac tagaagagaa aaatatggtt tgaatgaatt
    25021 tactccaaaa gaagagggta gtttttggga tgatttaaag gaaagtttaa gtgaaccaat
    25081 gatagttatc ttgattattg cagcagtagt aagtgcagta attggggaaa ctcatgatgc
    25141 aatagggatt gtaggtgcta tagcaatagg tatagcaata ggtatgatta cagaaggtcg
    25201 ttctaagaaa gcagcagagg ctctttctaa gttgactgaa aacatagaag taaaagtatt
    25261 gagagatggg gaagtacatc aaatttctaa gagtgaattg gtaccaggtg atatagtata
    25321 tattgaaact ggtgacatgg tacctgctga tggtagactt atagaaagta taaaccttaa
    25381 aattagagaa gatatgttaa caggagaatc tgatgacgta tctaaaaagt gtgatgtagt
    25441 agtttctatg gaagagatag aatctaaagg agcagtagta gtacaggagc caatacctgc
    25501 aaaacagata aatatggtgt ttggtggtac acttgtagct tatggtagag gagctctagt
    25561 tgtaacttca attggagata atagtgaaat gggtaaaatt gctcaaaact tatcagaaac
    25621 agatgagcaa actccacttc agataaaact tggaaattta ggtggtttga tagccaaagt
    25681 ttctagtgca gtagcaggat tactatttat atttatggtt ttccaaatga taagtaagaa
    25741 tgtattaaat gtagatatgt ctggaatatt accgttttta gaatcaatag acccagttaa
    25801 aacagcattt acagtatgtg ttgcgttgat agttgcagca gtgccagaag gtcttccaac
    25861 tatgataaat atgacacttg caataacaat gcaaaaaatg gctaaaataa atgcattggt
    25921 tactaaaaaa gaagcttgtg aaacgatagg ttctgtttct gtaatatgtt cagataaaac
    25981 tggtacatta actgaaaata gaatgactgt agaagttgca tatgttgatg gcagatatat
    26041 tgaaagttca gaagaggaaa taaatagtta ttttgaagaa aactgtatga taaactctac
    26101 agctgatgta gagcacaatg atggtgatat taagtattta ggaagtgcta ctgaatgtgc
    26161 attgctttta tattacaaaa acgtagatta tagacaagtt agaaaaaatt ctaatatagt
    26221 agctcaaaat ccttttactt cagattcaaa gagaatgact tctgttatag gtcaagataa
    26281 tcaccatgta ctattatcaa aaggagcacc agaagtctta cttgaattat gttcacatat
    26341 tcaaagagga aaagacatag ttccattaac tgaaaatata aaacatgaga ttttagaaga
    26401 aataaagaaa ttgcaaataa aatcaatgag aactttaggg tttgcatata aagaaatctc
    26461 acaagctgaa gaagaagcag cagtaactgc tgaaagtgat gctatgaatg taagtgcaat
    26521 ggaaaataat ttagtattta gtggttttgt tggtataaga gacccactta gaaaagatgt
    26581 tatagagtct gtaaatacag caaataaagc tggtgtttct gtaaaaatgc ttacaggaga
    26641 taatataaat acagcaagag ctataggtga agagttaggc ctattaaaaa ataatatgag
    26701 agtggttgaa gcttcatata tagatacttt agatgatgaa gaattaaaac aagagataca
    26761 aagtatttca atcgtggcaa gaagtaaacc agatagtaaa atgagaatag tttcagctct
    26821 gcaaaagagc ggagatgttg ttgcagtaac aggtgatggt ataaatgatg ctccagcact
    26881 ttcaaaagca gatgttggta tagcaatggg tatatctggt acagaggtat ctaaaaacgc
    26941 ggcagacata attttaactg atgatagttt tagtaccatt gtaaaaggta ttaaatgggg
    27001 tagaggaatt tatgataact tccaaagatt cgttcaattc caattaactg taaatgtaat
    27061 tgcattttta gtggctataa tatctcaagt tatgggacaa gagatgccat ttactacaat
    27121 acaattatta tgggtaaaca tcattatgga tggaccacca gcactagcat taggtttaga
    27181 gccagttagg gaccatgtgt taaatagaaa acctgttgat agaaaagcca atataatttc
    27241 taagtcaatg gtgtatacaa tagtattaaa tgcattttat ataacagcaa tactaatgtt
    27301 acaatctaca tttaatttct taggagttga tgaagcgcat aagggaacag taatgtttgc
    27361 gttatttgct tttagtgcac tgtttaatgc atttaactgt agagagttta atgcagatag
    27421 tatcttccct aattttacac ataacaaatt agcactacaa ataatagtgt tgacaggaat
    27481 tgcacaagta atatttactc agctattcca agatttcttt aactctgtag caatggattt
    27541 tatgacatgg gtaaaagttt tatgtgtagc agcaagtgta attgtggtta atgaagttgt
    27601 aaaatgtata ataagactgg taaaaccaaa aaagactgct taaaacaaat tttttagaag
    27661 aaaacagact gactcaaaat atgaattttg ggtcagttct gaataaacat ttaaattggg
    27721 aggatagtta tgggtgactc aaaggtattt gaaaaaatat tctccagcca atcagataga
    27781 ggaaattaca ctccttcaaa gggatatcta agttatttta tttcgtatat tggtttagaa
    27841 gatgaagttt tgtacaatct cgagatattt aagacaaaac aaaatattga tagcaaaaaa
    27901 gatattgctt tatttactga tgttatagca aatcctagtg attttgatat tataaattat
    27961 tttaaaagtg gacttcaaaa atatagaact agcatggaag atgtagatat aaatattttg
    28021 ggatttgaag agattgatta taaaataaag caagcaatag atagagtgtt aaaagaagaa
    28081 gaaaaagaat ttactaatga tagagttaaa caaaatttta tagtgaaaat aatggcatgg
    28141 ataaaaattt atatcggtgc tttagatata aataaaaatg aagctccaaa agtaatattt
    28201 tatggagata taaaaaaaca tgaagtttat ttactcttaa tattatactt ggcaggtttt
    28261 gatgttttat atcttaatcc aaattcaaag agtaatatag atattttaaa atcagaaaga
    28321 tacaatatag agtttgaaga agccaacata atagaagaaa aaatttcttt tgaagaaagg
    28381 gttattttag gggaaaaaat agataaaagt tctgtaaaaa aagcttttac tgttggggca
    28441 gaagcatcaa agcgtataag tgaggaattg ttaaatgatg caggatttat aaaaccttgg
    28501 caactccaag atagaaaaat aaaaaatcta cttctaagtt caactgttga tgaaatatca
    28561 atatactgga atcaaccact taaattaaga ccaggattta agtttaatga tgctattgta
    28621 gaagctccaa attttctttc taagattaat ggaatatata acgataagaa tgaatatatt
    28681 aagtttttag atttattaag agattcggaa agttcaacat ttattgaatt taatggagat
    28741 gtagatagat tttcaaaagc ttttacaaga gaagctttta gtttatcctt tttattggat
    28801 tcaaaaggtg caatagataa aaactctgtt ttaaataata aagattattc catatcaaca
    28861 ctagcattga atcaacaaat tatgatttta gagaaagtgg aagagttgtt agaaggaagt
    28921 atgtttttga atggtttaag tggagaagac aagataaaag gtctatttac agtacttcac
    28981 atggataaga aatttgttca tatgatgaac aatttcgatt actcacttat aaacccaaaa
    29041 ttgattatat acatgtacaa gagtattgta tttgataaag aaatagtttt tcttatgctt
    29101 ttacttagta agattggatt tgatattatc atattatgtc caggaggaga aaacaatata
    29161 gagaatgtta taaataacca attgattgat gtacacagat tggataaaat ggtatatgac
    29221 cttaaattaa attcgcttga aaatgatata cctttactta aaaaaatttt tggaaagagg
    29281 agacgatttt agatggggat aaatataaat agtttttcaa aagataagaa ctctgtagag
    29341 gttactgaga atttgcctac agcagttcaa gaagaaaact tcgatataat ggaatataca
    29401 aataataaaa aaaatgaact gagaaagtct aaggaagttg aggcattgac atcccttata
    29461 gaagtagaaa atccagatac gattttacag tttggtagga aagcatctga aggagtagca
    29521 agagtttctg atagcctttt aaatacaata aaattaaata gaaatgaaga aaattctaaa
    29581 atgctggttc atttaactaa aataatggac aagtttgatt tagacgattt tcaagaaact
    29641 aaggaaccaa atttcgttca aaaacttttc aaaaaagcta ataatgccat tgaaatgatg
    29701 tttcaaaagt atgaaacatt gggaggagaa gttgagaaaa ttcaaattga gcttgagcaa
    29761 tacgaaagag atatagcact ttctaataag cagataggtg ctatgttaaa tgaaaacttt
    29821 gagttttaca atgaacttca aaaatatatt gttgctggag aaatggcaat agaagaaatg
    29881 gataatgaaa tactaccttt ctttaaacaa aaatcagaga ctagtggaga ccaaatggat
    29941 gttgtcaatt atcaagaact attaaaagtt tatgatatgt taaatcaaag agtctatgat
    30001 ttaaggatag cagaaaatat agctatccaa acaataccta tgcttagagg tatgcaacat
    30061 aataattatg gtttaattag aaaaataaat agtgcatttg tcgtaacttt accagtattt
    30121 aaacaatgtt tatctcaagc tatattactt aaaaagcaag aattacaagc aaaatctcta
    30181 aaagcacttg atgacaaaac taatgaatta ttgcttagaa atgcacaaaa tgtaagtact
    30241 caaagtgcac aaatagctag aatggctgga acaagttctg ttcaaataga aacattggaa
    30301 aaaatgtaca atactatcaa atctggtata gatgaaacta tgagaataga agaaaacaat
    30361 agagctttaa ttaaggataa tacaaagaga ttggaagaat taaatacgac tataatttat
    30421 aataagtagt attatattaa gggctaattt gtataaagtt ggccctttct atgtatatga
    30481 ggaggctaga cattgaaata tttcgattat atctgcaaag atgatttgga gagaattttt
    30541 ttgaaggagc cagaagattt tagtgctaag actgaaaaag atgtgttgaa atatgcactg
    30601 ggcgcttttt tatacgttcc agctactcaa tataatatga tttataagag cattataggg
    30661 gatgttaagg gagttagacc attagctatt tgtttagaag atgctgttgg agtaaatgga
    30721 gagttagagg ctatagagaa tcttagatta attttaaaaa atattagcaa tgaaagtata
    30781 actaataaag atggaatacc actaattttt gtaagaataa aagatgtgga gcaactgttg
    30841 agaattaaag agattataat taaaaatagt cattttataa caggaatatt aattcctaaa
    30901 gcaaattcgg agttaattga aaattgtata gaagctttag attctatgaa tcttcaagat
    30961 atgtatgtta ttccgatagt agagacaaaa gaatttatat ataatgaaaa aaaagaactt
    31021 agttttacta atttgtacaa tgctatttta agacataagt caagaatatt aagcattaga
    31081 gtaggcataa ctgatatatt agggatgtat ggtataagga gagataaaaa cttttctata
    31141 tataataatt tgatttgttc ttcatttata ttagatataa tcacatatct tcaaagacca
    31201 gagttagata tacctataag tggtggagta tcagaatttt ttgatatgac gaataaagat
    31261 ataagaaata agtatataga agaaatatta ttggataaat atcatggatt aattggaaag
    31321 accgtaattc atccaatgca aattcaaatt gtacaagcgc tatctacagt atcatatgaa
    31381 gattttactg atgctttgga tatactggat agtacagaca gtaagtatgg tgtgagcaag
    31441 ggtgtattag gagagagaat gaatgaaaca aatccacatt ttttatgggc taaaaaaaca
    31501 ttgattctat ctaaaatata tggtgtatta aataaaggag tagactatga agaattgctt
    31561 aaattttaat tgtgagattg acattattga taatccattg aatttagaac taaatgattt
    31621 tttagacgta ggaataagaa ataatagcaa aagacgtttt ttgtttatct caaagaaact
    31681 cggtaaacat ttagcatgta agccaagtga gatggataat ttgggaaaat taatggctac
    31741 aatttataat gaaaaaaata aggaagaatc aaatggtact gttatagctt ttgctgaaac
    31801 tggtacagct gttgggcata gtttttttga ttacttatgt ggagattatg aatttattca
    31861 tactactaga gagcagtttg acgagttaga aaatctggaa tttttagagg aacattccca
    31921 tgcaacagac cagaatttat actttggtat gcttaacaac tttaaatttg gagatgagat
    31981 aatattggtt gatgatgaga ttaccacagc caatacatgc atgaatataa ttaggaaaat
    32041 tcaaagcatt tatcctaaaa agaaatacac tatatgctca atactcaatt gggtaagtga
    32101 tgaaaattta agtaaagtta ctcgtttaga aagagagcta gattgtaaga tagattttgt
    32161 atacttattt aaaggaaact ttaaatttta tatagatgaa gatattattt caaattacaa
    32221 cgataattat agtattacta aattagagac tatttcaagt gataaagtaa atttagtagt
    32281 aaatcatatt tatgttgatt tagaagatta tattggaaat aagaaatatg taaaatatac
    32341 aggaagattt ggaattaata gaagagaaca atttagatta aaagaaatcg ttaagagaga
    32401 aagtaaaaaa ataactatgg ccagtaaaga atctttaaaa aatgaaaaag aaaagattct
    32461 atttttaggt actgaagaat ttatgtatat acctatgctg tttgcaaaag aaaaagaaaa
    32521 tcaatatgat atatactatc attcaacaac aagaagtcca attattaata ttgataagaa
    32581 taattatcct attaaaagta aatttatgct aaagagtttt tataatatag atattcaaaa
    32641 ttatatttac aatatagata aacataattt ttctaagtgt tatttatttg tagagctgaa
    32701 taaaagtgaa aattcttatc tagaatttat tgatataatt aaaaaaacaa gtataaaaga
    32761 attaactata gtatgttgta gctaaagtgt tttaacagga taaaatatat cacgatttta
    32821 agataggagt tgagtcatat gagagatttt agcacgtatt ctaaagatga tgttattttt
    32881 ttattaaaag atatatcaaa tttaattgaa gaagaaggaa ataaagaaag agaattaaaa
    32941 atacaaaatg gtagacatta ttcagaaatg ataccaatag agtatgaagt tagtgaagat
    33001 tatctgaatt tatatcatga gaaactaaga gaaaataaag ataagcttgc attttctata
    33061 ggagttatgt gtgaaaaaat aattaaaaaa aatggaaatg atgtagtact agtttcactt
    33121 gctagagcag gaacacctat tggtattttg gcaaaaagat atataagaag caagtataat
    33181 gtaagtttac ctcactatac aatctctata ataagagata agggaataga tatgaatgca
    33241 attgaatata tagtaaagaa tcatccaagt tcaaaaattc aatttttaga tggatggact
    33301 ggtaagggaa ctatatcaaa agaacttgaa aaagcatgtg atgaacttaa tgttaaattt
    33361 aaaaaacatt ttgactcaac acttgctgta ttagctgacc ctgctggata ttcaggactt
    33421 tatggaatta gagaagattt cttaatacca agtgcatgtt taaattcaac cgtttctggt
    33481 ttagtaagta gaactgtact aagagaggat ttaattggta aaaatgactt tcatggagct
    33541 aagttttata gacatttaaa agataaagat gaatctatga actatatcga aactatagaa
    33601 gaatgtttta aaaatcaatt taagaatata tctgatgaag ttgaaaactg ggaaagtgac
    33661 attataacaa gagatggata ctttgatgtt ttaaatataa aagaaaagta taacataaca
    33721 gatattaact ttatcaaacc aggtgtaggg gaaacgacaa gggttttact tagaagagtt
    33781 ccgtataaga ttcttgttaa agacttaaat gataaatctt tagaccatat attcatatta
    33841 gctaaggaga aaaatgttga agttgaacaa atggatttaa aagcctataa atgttgtgga
    33901 ataataaaaa atatgaaaga tatttaggaa atatattaga caggagaata ttgaatgatt
    33961 gttttttcag atttagacag gagtatcatt tactccaata aatttttaaa tgctgatagt
    34021 aaatatgcta atatagaaat ttatagggaa aaagaaatat cttatatatc tttagatact
    34081 ataaatttaa taaagcaaat acaatattat ggtatgttta tacctacaac tactagaaca
    34141 gtggagcaat ttaagcgtat agaatttaat aaatatggga tttattttcc ttggagtata
    34201 acttcaaatg gaggagttat acttaaagat aatgaaatat tgaaatcatg gagtgaaaaa
    34261 atagataaac taaaatctga ttatgagccc attgaaagta tgattcataa atttaaagac
    34321 tatttgaatg tagatggaat aactaatttt aaagttgcag aagatacatt tttttatata
    34381 gttgttgatt tatcaagatt taatttggat tcaatcaaag aatatacaaa tatattggaa
    34441 tcaaaaaatt ggaagtttta tgtgagtggc agaaaaatat attttatacc aaaagaaatt
    34501 tcaaaagaaa atgctataaa atacttgact aaagaattag gaatagaata tttttatgca
    34561 gttggagatt ctattatgga ctatggtatg cttaatatct caaataaatc ctatgtattg
    34621 aagcatggtg atataaataa aaatgaaata gaaaattcat ttatatcaag ttctttcaat
    34681 ggaatgagtg gaactgaaga gatactatct aacattttag acgagaactg cctacttaac
    34741 atataatgac tgatatataa ataataaact agaaaaatct gaaataaatt atagtaaagt
    34801 ttatcatact aatttatttc agatttttat caatttatat ttaagtaaga actcaacatg
    34861 ttaaaatgaa ggtggagtca ttgcccagac tgagatacat acctcatcat cataattttc
    34921 atacacatgt ggtatagtac tgttaaaata aaaactatct ccttcctcca atagatattc
    34981 cttatttcca agtgttatct tcattttacc ttttattata tagccacatt cttctccttc
    35041 gtgtgtcaca aattcactgt ttttttgtgt atgaccatct agcgtaacaa gtataaattc
    35101 tatttttttc ccagataaat taggaacaag aagttcataa aattttgtag aatcattagt
    35161 tactattttt tttcgattat ttttctttac tactatatca gagtcttctc ttccaatctc
    35221 ttcaaaaaaa taacctatat ttatatcaag agcttttgat attttccaca ttgctacaat
    35281 agatggaaca accatattac gctcaatttg acttattaag cctgtactta aatctgaatt
    35341 ttttgctaaa gtagagatac ttatattttt agattttcta agagatctaa ttttgcttcc
    35401 aacatctata ttcattagat acaaaccccc tcagacatga ttataacata taatttataa
    35461 agattaataa aataaaaaaa aagttttaca atacaagtat tttttatgct atattgaatt
    35521 ttctgaaaag atgcattata atagtattaa tattcaatat attgaatatt gataacgata
    35581 ttttaattta atgaaatgga ggtaattaag atgaagagtt ttgtaagtcc tgataatatt
    35641 tgggtattat gggcagttgt aactggatgg gcagcattta gtatttattt ggaacaaaag
    35701 tacaattggg catcaaaagt gtcgggagca ataatagctc ttgtaggagc aatgttatta
    35761 tcaaatctaa atattatacc agtagagtct gttgtatatg accaagtatg gggatatgtt
    35821 gttcctttag ccatagcttt attgttatat caatgtaaca ttaaaaagat atggaaagaa
    35881 agtggaagat tgctcattat atttcttgta ggttctgtag gaactgtact tggagctatg
    35941 attggatttt tagcattaaa aaatgtagta ccagatttaa atattgttgc agctatgatg
    36001 acaggttctt atataggtgg aaatgtaaac tttgctgcta tgtcaggggc gtttgatgcg
    36061 ccaggagaat tagtatcagc aacagttgta gcagataatc ttttaatggc attatatttc
    36121 tttgtcttaa tagctatacc atcaattgga ttttttagaa aacattttaa acatccacat
    36181 gtagatgaaa tggaaagtat aggtataact gaaggagaaa cagtagcagc aaattattgg
    36241 ggaagaaaag aaatatcttt aaaagatata gcaatagcca ttggtagcgc ttttataatt
    36301 gttgcagtat ctgtagaact atcaacttgg tttaaagcta taataccatt atcaaatcct
    36361 tttttagcaa tgttaaatac tttatttgga aatcaatatc taataataac tactttgact
    36421 atgttgtttg ccacatttat gcctaatttc tttggtgata taaaaggagc acaggaattg
    36481 ggtacatttt taatatatat attctttgtt gtagtaggtg ttcctgcttc aataacatta
    36541 ataattcaaa aatcaccatt actactttta tactgcggaa taatggtact aataaacatg
    36601 ctagttacat ttatagttgc aaaaatattt aagtttagtt tagaagaagc tattcttgca
    36661 tctaatgcaa atattggtgg tcctacaaca gcagcagcta tggcaatatc aaaaggatgg
    36721 tctaagctag tagggccaat acttatagtt ggaacatttg gatacatagt cggtaattat
    36781 tttggtcttt tagtaggaaa tattttgata taattttacg tgaaaaaaag ttgtttttta
    36841 gaaagatttt tatttattag aaagattttt atttaattgg aggttgttat gattttcgat
    36901 ggacattcag atacttgggc agatgtaaca ataagaaggc ttaacgggga aaaagatgta
    36961 tttagaagaa tccatcttga taattttaaa agagcaaata tagaaggagc tatttttgta
    37021 atatggatag acccaccata tgataaagag cctgaaaaaa gagttaaaca aattataagc
    37081 tctataaaag atgaaattga agatatgaaa gatgttgtaa acatagtaaa aaaatattca
    37141 gatatagata aaggtataag tgaaaacaaa ataaatattt taattggtct tgaaggatta
    37201 agccatattg gaagaaatat agatttacta gattattttt ataaagaagt tggtgcaaga
    37261 catgcatcat taacttggaa tgaacagaat gaacttgcta caggatgttt aggggatgaa
    37321 aatcgtggtt taactgaaat aggtaaaaaa gcagtcaata aaatggaaaa attgggcatg
    37381 atagtagatg tgtcacattt aaatgaaaaa tcattttggg atttaatatc tgttgcaagt
    37441 aagccagtta tagcttctca ttctaatgct aggagtttat gtgatgctaa aagaaatctt
    37501 acagataatc aattaaaaga aatttcaaat acaggtggat tagttggaat aaatagtttt
    37561 agaggattta ctaatagtaa tcctaagaag caagatttaa tacatttggt tgaccatata
    37621 gactatatgg taaatcttat aggtatagaa catgtatctt ttggttttga ttttagtgat
    37681 tacttaggga aagagactat aggttctttt actggaaatg ctagtgtgcc aagtgtagat
    37741 ggtcttgaaa gcacacatac agcacagaac atagtagtag agcttgaaaa tagaggttat
    37801 aaaaagaaag atatagagtt aatctctagt ggtaattttt ataggctctt taaagatata
    37861 ctaaaataat ataataaaga acttaaattt ataaaatagt atatttatac aataatatct
    37921 acatatttaa attggcgttc ataatttatt aaattaaatt ttaatgttac tagaagtttc
    37981 aattctagta acatttttta tgttaaaaac agatatagat atgtattgac aatgataatt
    38041 attattgata aactataaaa gtgaaaatga taataatttt cattttaatt aataaaagat
    38101 ttttaaggag ggagaatgaa gaaaaggtat ttagtcatag gaataataat tttgtcttat
    38161 ttttctttat ttataggagc tgaagatata aatataatgc atatatttgc caaaaatcag
    38221 cataaactta tgatatttat catgagtaga ataccaagat taataagtat attgattgct
    38281 ggtgtaggaa tgagcatagc aggtcttata atgcaacaga taagtaagaa taaatttgta
    38341 tcacctacaa caggtgctac aatagatgca gcacaatttg ggatagtaat atgtatgctt
    38401 ttagtaccaa ctgcctctat ttttacaaag acaataatag catttgtatt ttctcttgta
    38461 gggactttta cgtttatgaa aataataggg aagttacaat ttaaaaatat aatctttgta
    38521 ccattagtag gtataatgtt tggaaatata ataggttcta tgacggattt tatcgcgtat
    38581 aaatacgatt tgagtcaaaa tgttagttct tggatgcaag gtgacttttc tatgatactt
    38641 aaaggaaatt atgagatatt atatatcaca atacccctta taatattagc atatatttat
    38701 gcaaataaat ttactgttgt tggtatgggt atggattttg cgacaaactt aggtcttagt
    38761 tacaaaagaa ttgtcaatat aggtttgata atagtagcac ttgttacagt atgtgtagtc
    38821 gttacagctg gtaatatccc ttttataggt ctaatagttc ccaatatcgt atccttgtat
    38881 atgggtgata atataagaga aagtatatgg tatactggtt tacttggagc aatatttgta
    38941 cttatatgtg atatttttgg aagaattatt atttatccat atgaaatatc tatagggctt
    39001 acagttggag ttataggaag tatactattc ctttatttaa tattaaggag gaacgtaaat
    39061 gaagcttagt ctcaatcaaa aaatttactt tgtaagtata ttactattca tatcaatagc
    39121 actttttgta atttatggaa tagacatgaa tcacttagaa tatgcattat cacaaagaat
    39181 accaaaaata tttgctatgg tattaggtgg aggatgtata gcatttacta ctgtagtgtt
    39241 tcaaacaatt acaaacaatc aaatattaac accaagtgta ctaggtttag attcattgta
    39301 tgtaatgatt caaactataa tagtattcat atttggttca agcagtagtc tgattataaa
    39361 tgaaaattat aattttatta ttaatgtagc tatgatgatt ggagcttcat tgttattata
    39421 taagacatta tttgaaaaaa ataaaaataa tattttcttt ttaatcctag taggaatgat
    39481 atttggaacc ttatttaaaa gtgcaacaac atttattcag gtaatgatag acccgaatga
    39541 atttttagct ttacaaacca gtataatggc aagtttaaac aatataaaca ctaatgtatt
    39601 gttaatagca tttataataa ttattgccat aatacctttt atatatgatg aaataaagta
    39661 tttagatgta ttgtcgttag gtaaagaaca agcaattaat ttaggtgtag attttgataa
    39721 agcagttaaa aaaatgataa tattaatagc aattttagtc tcaatatcaa cagcacttat
    39781 tggacctatg acatttttag gacttttact tgctaatata acaagagaaa tttttaaaac
    39841 atataagcat acatacttga tttcgggttc tatgttgata gggatgatta cattgataat
    39901 aggtcaattt tttatacaac atgtatttaa gtttgataca actttaagtg tagtaataaa
    39961 ttttatagga ggaatttact ttattcaatt actattaaag ggggcaaata gatgatagag
    40021 ataaaaaata tatttaaaag atataagaat aaaaatgttg tagatgatgt ctcttttagt
    40081 atagaaaagg gaaagataac atcttttata ggaccaaatg gagctggaaa aagtacagta
    40141 ctatcaatag ttacaagact tataggaggt gatggtggag aagtaataat agaaggaaaa
    40201 agcttgacta attatagcaa taaagaatta gcaaaaaaaa tagctattct taaacaatct
    40261 aacaatataa ctttaaagct tacaataaga gaattagttg gatttggaag atttccatat
    40321 agtgaaggta atctaactaa agaggatgaa aattatattg atgaagcaat agaatatatg
    40381 aagttgactg atatacaaca taagtattta gatgaattga gtggaggtca aagacaaaga
    40441 gcttatatag caatggtaat agctcaagat acagagtaca tattacttga tgaaccactg
    40501 aacaatttgg atatgaacca ttccgtacag atgatgaagg tacttagagg tctttgtgat
    40561 gagttagata agactatagt attagtaatg catgatataa attttgcatc atgttattca
    40621 gataatatag ttgcattaaa aaatggaaaa gttaaaaaag taggtcgtac agatgagata
    40681 gtaaatgaaa aagttttaga agatatttat gagatgaatt ttaacattaa gaatataaat
    40741 ggaaatcgaa tctgtattta tttttaaaat attgtatatg gaaataaact tgctatatga
    40801 ttttttataa agtttttaaa ttaaaataaa gattaatagg agagaggaaa atattgatat
    40861 gaataaaaaa gcagcaatag tagcaacagt agctattata ggattagtga cagtgtttgc
    40921 attaggtgga agtaaaaaga atgaatcaaa aacatcagaa aattcaaata atactatgaa
    40981 gataactcat aacttgggag aaacagatgt aaaattaaat cctaaaaaag tagtagtatt
    41041 tgattattcg gctttagata caatggatgc attaggtgta gctgagaatt tagtaggact
    41101 tccaaaagcg agtttaccag catccttaga aaaatataag gatgacaagt atgcagattt
    41161 aggaggctta aaagaaccag atttagaagg tataaagtcg gcaaatccag atttaattat
    41221 aataaatgga agacaagaag atttttatga gcaattgtca aaaatagcac caacaataag
    41281 tacaagtaaa gatgataaga agtacttaga atctgttaaa aataatatag acaaaatagc
    41341 aaaaatattt ggagtagaag aaaaagcaaa tcaagaattt agtaaaattg aaaagaaaat
    41401 agaaactttg aataaaaaag taacagataa aaatttaaat gctttaacta taatggtaaa
    41461 tgaaggtaat ttaagtgtat ttggtgaaga atcaagattt agtatattat acaatagttt
    41521 tggatttgaa aataaagata aaaatataaa agaatcaagt catggacaaa atattacttt
    41581 tgaatatata gctaaacaaa atccagaagt tatgttcgtt atagatagag gaatagctac
    41641 tggcagtgat gtaaaagaaa gctcaactgc aaaatctgtt ttgaacaatg atataataaa
    41701 atctatggat gcatataaga atgataatat aatatattta gattcaccaa catggtatgt
    41761 aaatgatggt ggtctaacat ctttaaataa aatgatagat gatgcttcaa aagcggtaaa
    41821 ttaataatcc gatataatca aaatgtattt tttataaaat gattatcaaa taaactagga
    41881 gtttttaaga actcctagtt tattttttgc ataaaaaaga tatagtttaa acaataatat
    41941 tatctataat aagataaatc tattcaaaat ctaataaaat atgaagttat actagacaaa
    42001 aagaataact cttaaa
//
LOCUS       DAEPXW010000029        40782 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.030, whole genome shotgun sequence.
ACCESSION   DAEPXW010000029 DAEPXW010000000
VERSION     DAEPXW010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40782
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.030"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            172..831
                     /gene="cprR"
                     /locus_tag="KRM55_001482"
     CDS             172..831
                     /gene="cprR"
                     /locus_tag="KRM55_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBH1593731.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1042..2100
                     /locus_tag="KRM55_001483"
     CDS             1042..2100
                     /locus_tag="KRM55_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH1593732.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2351..4495
                     /locus_tag="KRM55_001484"
     CDS             2351..4495
                     /locus_tag="KRM55_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2765..2767,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HBH1593733.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4544..5377
                     /gene="fdhD"
                     /locus_tag="KRM55_001485"
     CDS             4544..5377
                     /gene="fdhD"
                     /locus_tag="KRM55_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBH1593734.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCTPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5346..5561
                     /locus_tag="KRM55_001486"
     CDS             5346..5561
                     /locus_tag="KRM55_001486"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593735.1"
                     /translation="MQIHRELSKSENEYMCTKKEKQRYSKCEICGVLIDDTDKVYNNT
                     YNLCKKCKRNISAEKIVKYINIYDESK"
     gene            5619..6170
                     /locus_tag="KRM55_001487"
     CDS             5619..6170
                     /locus_tag="KRM55_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1593736.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6195..7571
                     /locus_tag="KRM55_001488"
     CDS             6195..7571
                     /locus_tag="KRM55_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH1593737.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7571..8086
                     /locus_tag="KRM55_001489"
     CDS             7571..8086
                     /locus_tag="KRM55_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1593738.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8164..9447)
                     /locus_tag="KRM55_001490"
     CDS             complement(8164..9447)
                     /locus_tag="KRM55_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBH1593739.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9635..10057
                     /locus_tag="KRM55_001491"
     CDS             9635..10057
                     /locus_tag="KRM55_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBH1593740.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10159..11097
                     /locus_tag="KRM55_001492"
     CDS             10159..11097
                     /locus_tag="KRM55_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBH1593741.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11283..13307
                     /gene="ligA"
                     /locus_tag="KRM55_001493"
     CDS             11283..13307
                     /gene="ligA"
                     /locus_tag="KRM55_001493"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBH1593742.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKEMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13467..14816
                     /gene="rph"
                     /locus_tag="KRM55_001494"
     CDS             13467..14816
                     /gene="rph"
                     /locus_tag="KRM55_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBH1593743.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKIIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14816..15286
                     /locus_tag="KRM55_001495"
     CDS             14816..15286
                     /locus_tag="KRM55_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1593744.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            15480..16766
                     /locus_tag="KRM55_001496"
     CDS             15480..16766
                     /locus_tag="KRM55_001496"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBH1593745.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16916..17500
                     /gene="clpP"
                     /locus_tag="KRM55_001497"
     CDS             16916..17500
                     /gene="clpP"
                     /locus_tag="KRM55_001497"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH1593746.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17519..18769
                     /gene="clpX"
                     /locus_tag="KRM55_001498"
     CDS             17519..18769
                     /gene="clpX"
                     /locus_tag="KRM55_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBH1593747.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18840..19367)
                     /locus_tag="KRM55_001499"
     CDS             complement(18840..19367)
                     /locus_tag="KRM55_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1593748.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19355..19867)
                     /locus_tag="KRM55_001500"
     CDS             complement(19355..19867)
                     /locus_tag="KRM55_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1593749.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            20047..22410
                     /gene="lon"
                     /locus_tag="KRM55_001501"
     CDS             20047..22410
                     /gene="lon"
                     /locus_tag="KRM55_001501"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBH1593750.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLIEHMDEVLEQALLKSGENNEN"
     gene            22400..23011
                     /locus_tag="KRM55_001502"
     CDS             22400..23011
                     /locus_tag="KRM55_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBH1593751.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23276..24646)
                     /locus_tag="KRM55_001503"
     CDS             complement(23276..24646)
                     /locus_tag="KRM55_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1593752.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24821..24936)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25224..26303
                     /locus_tag="KRM55_001504"
     CDS             25224..26303
                     /locus_tag="KRM55_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1593753.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26694..27374
                     /locus_tag="KRM55_001505"
     CDS             26694..27374
                     /locus_tag="KRM55_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH1593754.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27367..28746
                     /locus_tag="KRM55_001506"
     CDS             27367..28746
                     /locus_tag="KRM55_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH1593755.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28917..30002
                     /locus_tag="KRM55_001507"
     CDS             28917..30002
                     /locus_tag="KRM55_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH1593756.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            30056..30415
                     /locus_tag="KRM55_001508"
     CDS             30056..30415
                     /locus_tag="KRM55_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBH1593757.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30468..31340
                     /locus_tag="KRM55_001509"
     CDS             30468..31340
                     /locus_tag="KRM55_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBH1593758.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYISNIGMII"
     gene            31341..31784
                     /locus_tag="KRM55_001510"
     CDS             31341..31784
                     /locus_tag="KRM55_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593759.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSRHTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEIEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31799..32383
                     /locus_tag="KRM55_001511"
     CDS             31799..32383
                     /locus_tag="KRM55_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593760.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANLLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32636..33673
                     /locus_tag="KRM55_001512"
     CDS             32636..33673
                     /locus_tag="KRM55_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH1593761.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33754..34119
                     /locus_tag="KRM55_001513"
     CDS             33754..34119
                     /locus_tag="KRM55_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593762.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34124..34441
                     /locus_tag="KRM55_001514"
     CDS             34124..34441
                     /locus_tag="KRM55_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593763.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34489..36093
                     /locus_tag="KRM55_001515"
     CDS             34489..36093
                     /locus_tag="KRM55_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593764.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36217..37845
                     /locus_tag="KRM55_001516"
     CDS             36217..37845
                     /locus_tag="KRM55_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH1593765.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38110..39459
                     /locus_tag="KRM55_001517"
     CDS             38110..39459
                     /locus_tag="KRM55_001517"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBH1593766.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39615..40694
                     /locus_tag="KRM55_001518"
     CDS             39615..40694
                     /locus_tag="KRM55_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH1593767.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
BASE COUNT        16756 a         4308 c         7346 g        12372 t
ORIGIN      
        1 atataaagtt tttgaaatat aaagtttttg tatctaaaat attttatttg taaaatagta
       61 attaattatt gtaagctata atatgagagt attatggtta atgtgaattt taaagatatt
      121 attaaatata taaattagaa tgctattaga tggataaatg gaggagttat tatgtctaag
      181 atattagtag tagatgatga gttagatatg ttaaagttga ttgaaaatgt gttgaaaaga
      241 gatggacatg aagtaaaggt aattagtgat gtagaaaagg ctatgaacat ggattttaat
      301 tattttaatc taataatatt agatgttatg atgcctaaga tggatggttt tgaagtatgt
      361 aaaactataa gaaataaggt tgattgtcca atactgtttt tgacagcaaa aaatatggaa
      421 agtgatatta tgtacggtct tggtataggt gcagatgact atataaccaa accttttggt
      481 gtaggagaat taagggctag gataactgct catttaaggc gagaaagtag agaaaaaaag
      541 aatttattaa ctatctcaaa tgttcaattt aactttttag gcaaagaagt ttcaattgat
      601 ggtaaaaaaa ttaattttac taaaagtgaa tatctaatat gtgaatttct agcaaaaaat
      661 aagggacaag tattttcaaa agaaagaata tatgagtcgg tatatggttt tgatggagaa
      721 agtgatataa gtactatcac agagcatata aaaaatatac gaagcaaatt aaaacaatat
      781 gatatttata caatagaaac tgtatggggg atagggtata aatgggtgta ataagtataa
      841 gtgttgttta gtgaaaatat tatatatatc tacaaaatgt ttgtaaaata ttaatctata
      901 tattaaaatt taatttatag attaatattt tttgtaaatg acaaaattgt aaggtatttt
      961 gttataaaat attaagattc atagtgtata ctaataatat agtatttagt ataaatcttg
     1021 agcaaaggat ggttatttct aatggataga ctaaagaata ttagaaagag tttactacag
     1081 tatacatttt tatttttgtt aataggtata acaatttacc tagtgtttaa aacattggat
     1141 attaaaatgc tatcaaatgt tatggttatg gtagataaga agtttttatt cataggtgct
     1201 ttggcaataa tgtgtcacat aatgcttgaa ggagtagtaa tgaagataat tatagaaagc
     1261 actcacaaag ttaatattag atttattggt tttaagctag ccattatggg attttattat
     1321 aatttaataa ctccttttgc ttcaggaagc caaccagtac agatatatgt acttaaaaaa
     1381 tgtaaaatgc cacttagtaa ggcaagtgca gttgttacca ataagtctat tatcttccaa
     1441 atagtagtta ctttttattg tacaatactt gttttaatga attttgctat gttagaaaaa
     1501 caaatgaaaa tgattatgcc tctagtgttt ctagggatag ccattaattc atttgtctta
     1561 attatgataa tattagttat tttaaatcct aaaaaaataa aatattttat gagaattact
     1621 ataaagcatt tatcaaaaat taagttttta aaatttttag ataataagat tgaatccata
     1681 gaaagtttta tagatgatta tagtaaagca ataaattttt ttgcaaagaa taaaaaggta
     1741 ttaatttcaa ctataatagt aacttttatt caattaagtg cttactttag tgtttcattt
     1801 tggatatata aagcatttaa tttacaaggt tatagctata tttatatact gacattacaa
     1861 gcatttttat atatggcaat atctccaata ccaacacctg ggaatgtagg agctaatgaa
     1921 ttagcctttt tcactatatt caaatcagta ttccctcaac ctttgatggg atatgcagta
     1981 tttttatatg gtggatttat gtactatttg attctgattg gaagtggaat atttactgta
     2041 attactcact atagaatgaa aaatagaatt ggcagaaata ttgttttaag tgaaaactaa
     2101 ataagtttaa agaatatata ttgagtatat taaaaaatat gtcataagaa ctagaatatt
     2161 ttaattaaat ggttgaaata taaagattat tatgacatat tttttttgaa atttaagagg
     2221 aattgtgaga aaattgttga atttaataga tagtattgca aaatatttat gattttgcat
     2281 attataaaaa cactcattat ctttaagata aattttactt atcaggggat aaatctaagg
     2341 ggggaattgt atggagaaaa aaattttaac agtttgtcca tactgtggag ctggatgcca
     2401 attatatcta gtagtaaaag ataataagat attaagagct gaaccggcta atggtagaac
     2461 aaatcaagaa agtttgtgtt taaaaggtcg ttatggatgg gattttctaa atgaccctaa
     2521 aattctaaca cctaggctaa aaaagccaat gataagaaaa caaggtgtac tagaagaggt
     2581 tgaatgggat gaggctataa actatacagc ttcaagacta aatgaaatta aagaaaaata
     2641 tggacctgat tctattatgg gaacaggttc tgcaagagga cctggtaatg aagcaaacta
     2701 tataatgcaa aaatttatga gagctacaat aggaactaat aatgttgacc attgtgctcg
     2761 tgtctgacat gcaccatctg tagccggtct ggcttactca ttaggtagtg gtgcaatgtc
     2821 taattctata ccagagatag aaaatgcaga tgttttattt atatttggat ataatggagc
     2881 agattcacat ccaatagtgg caaatagaat agtaaaagct aaaaaaaatg gtgctaaatt
     2941 aattgttact gaccctagag taactgaatc tgcaagaatt gctgatatac atctacctat
     3001 aaaaggtgga acaaacatgg ttttagtaaa tgcttttgga aatgtattaa tagaagaagg
     3061 tctttacaat aaagaatttg ttcaaaatca tacacaagga tttgatgagt ataaagaaat
     3121 tgttaaacca tatacagcta aatatgctga aaagattaca ggaatcccag aagagcttat
     3181 aagaaaagct atgagagaat atgcaaaagg taaaaaagct atgatacttt atggaatggg
     3241 tgtctgtcaa tttggtcaag ctgttgatgt agttaaggga cttgcatcaa ttgctctact
     3301 tacaggtaat tttggtagag aaagcgttgg aataggacct gtacgtggac aaaataatgt
     3361 tcaaggagct tgtgatatgg gagctcttcc taatgtatat cctggctatc aaaatgtaac
     3421 tgatgataag ataagagaaa agtttgaaaa agcttggggg gtaaaattat ctcctaataa
     3481 tggttatagt ttaactcaag ttccaaattt agtactaaaa gagaaaaagc ttaaagctta
     3541 ttatatattt ggagaagacc cagtgcaaag tgacccagat gcatcagaag ttagagaagc
     3601 attagatgaa ttggaatttg tcattgttca agatatattt atgaataaga cagcacttca
     3661 cgctgatgtt atacttccag ctacttcttg gggagaacat gagggagtat atacatgtgc
     3721 agatagagga ttccaattga tgagaaaagc tatagagcca caaggagatg taaaaccaga
     3781 ctggcaaatt ataagcgaaa tttctacagc aatgggatat cctatgaatt ataaaaatac
     3841 taaggaaata tgggacgaac ttagacaatt atgtccaagt ttcttaggtg ctacttatga
     3901 aaagatagaa actcaaggat gcgttcaatg gccttgtaag agtgaaagta tggaagataa
     3961 aggaactatg tatctgtatg aaggtcaaaa gttttctact cctaatggta aaggtaattt
     4021 gttcgctgct gaatggagac cccctatgga agttgaagat gatgaatacc catttagttt
     4081 atgtactgta agagaagttg gacactattc agtaagaaca atgactggta attgtagaac
     4141 acttagttca ttagaagatg aaccaggacg tgttcaaata aattctaatg atgctgaaaa
     4201 attaggaatt gaagatgatg aattagttag aattagttca agaagaggaa gtgtaataac
     4261 aagagcaaca gttactgata gagttaagga aggtgcaaca tatatgactt atcagtggtg
     4321 ggttggagct tgcaatgaac ttacaatagc aaatttagac cctatatcta aaacaccaga
     4381 gtataaatat tgtgctgtta aacttgaaaa acttgaagac caagaattag cagaaaaatg
     4441 tgtaagagaa gagtatcaaa gtttgaaaga caaaatgaca gctacaaata tctaatgatt
     4501 tattagattt aagatttata aaaggcagaa aggctaatat tttatgaaca atatatactc
     4561 aaaaactaaa ttacaagaaa atagtaagga taaagttttt gaaaatagtt atagtctagt
     4621 ggactacaaa tatttaaatt cttttaatgt agaagtaagc aaaataaatg aacatgaagt
     4681 atcaatagat aatgaagaaa taattgcaga atatccactt agttttattt taaatgataa
     4741 atatgtaaat acatttttat gtaccccata taatttagag gaacttatag taggattctt
     4801 gaaaacaaaa ggatacatag aaaacaaaaa aagcttatta aaatttgaga taaatgagag
     4861 tgaacgtttt gcaaaagtaa ctattcaaga gaaacaaaaa aatcaagatg agcaaattat
     4921 atttttaaat tcactagact atataacatg tactcctgta aagagcaata taaaaataaa
     4981 ttatgatacg atttacagta taatggataa aaatttaaat tcatcagaat tatttaaaaa
     5041 tactggtggg gtacatagcg tatctgtatt taattttgat aaaaaaatag tcacttgtga
     5101 agatgtagca aggcataatg caatggataa ggctattgga ttttgtgttt taaatgacat
     5161 aacattaaaa gataaaattg tggctgtaag tggaagaata tcattggaaa tgatattaaa
     5221 agcagctatg actcaaattc ctattgtagt atcaaaatca gcaccgacta atttatcaat
     5281 agagctttct aaaaaattaa atataacgct tattggattt gtaagaggaa gacggatgaa
     5341 tatttatgca aatccacaga gagttatcaa aaagtgagaa tgaatatatg tgtactaaaa
     5401 aagaaaagca aagatattca aagtgtgaaa tctgtggagt attaattgat gatactgata
     5461 aggtgtataa taacacatac aatttgtgca aaaaatgtaa acgaaatata agtgctgaga
     5521 aaatagtgaa atatataaat atatatgatg aaagtaagta gacatatgat gaaaataact
     5581 agagggttgg aaatatacaa attgaaaggt gggataatat gaaaaataaa ataggctctt
     5641 ttgtaatagc agacccaaac aaatgtacag gttgtagagc ttgtgaagta gcttgtttta
     5701 caatgcataa tcagcataat aatgtgggtt atacagttgg aacagttgat atacctgtta
     5761 tacctagact ttacttagta aaaggtgaca atttctgtat gccaatacag tgtagacatt
     5821 gtgaagatgc tccttgttta aactcatgtc cacaaaaagc tatagttaaa gaaaacaata
     5881 ttatgtctgt aaatgaagaa aagtgtatag gatgtaaaac ttgtctgcta gcatgtcctt
     5941 ttggagctat agacttactt ccacaatatg aagatggtaa agaagtagaa caagtaattt
     6001 tagatgaaaa taagaagata gcttataaat gtgacttatg taaagacaat gaaaaaatag
     6061 cttgtataag tgcatgtcct caggaagcat taaaacttgt tactccaata gatgacaaaa
     6121 aagctaagaa tagacaagct gcacttagtt tattgttaac aaataaataa aggatacagg
     6181 ggtaggtgac gtttatgata ataaatatag ataaggattt atgtactgga tgtagagaat
     6241 gttcaaaggt ctgtccagta aatgctattg aaggtgaaga gggaaagcca caagagataa
     6301 atttagatag atgtgttatg tgcggtcaat gtgttcaaac ttgtaaatct tatgcctcag
     6361 ttatagatga aggatttgag tttttacaag agaaaaaaca agaaagagag ataccagagt
     6421 ctataaatga acctatattt gcagcataca atgtatgtga tatagataag gtgaagaaag
     6481 ctttaagtga cccaaatgta ttcactatgg tccaatgtgc accagcagtt agagttgctt
     6541 taggagaaga ttttggatat tatttaggat acttaggtgc tgggaaaatg gcagcagcac
     6601 ttagagcttt aaattttgat agagtctacg atactaattt tgcagcagat ttaactataa
     6661 tggaagaagg tagtgaatta attaaaagag tgacagaagg tggaactctt ccaatgttta
     6721 catcttgttg tccagcttgg gtaaaattca tggaaaaaaa ttatcctaaa ttaactaatc
     6781 atttatcttc ttgtaaatca cctcagcaga tgggtggtgc aatatttaaa acttatggtg
     6841 cagagataaa taatgtagat gcatcaaaga tatttagtgt ttctataatg ccatgtacat
     6901 gtaaaaaata tgaatgtgat agagaagaaa tggattctag tggatataga gatgtagatg
     6961 tagtattaac tactagagaa ctagcttatt taataaaaga catgggaatt gattttaaaa
     7021 atttaagaga agaaaaattt gatagtcctt taggtagtta tagtggagct ggaactatct
     7081 ttggtgttac tggtggggtt atggaagctg ctataagaac aggatatgag cttataactg
     7141 gagaaagtat tcctgatgta gaagtaaaac aagtaagagg agaaaatggt tttagaaagt
     7201 caactattaa aataggagac ttagacttaa gagttggagt agtaagtgga ttaaaaaatg
     7261 taataccagt gcttgaagac ttggaaaaag gaaaattaga tgtagatttt attgaagtta
     7321 tgacttgtcc tgttgggtgt gtaagtggtg gaggtcaacc aaaaatttta ctagaagaat
     7381 ataaggaatt ggcttatgaa aatagaacaa aagcaacata cgtgcatgat gaacacttag
     7441 caattagaaa atctcatgag aatcctgata ttaaaaaact gtatgatgaa tatctggtag
     7501 aaccattagg agaaaaatct catcatctat tacacactac atattgtata ggaaaggaag
     7561 tggctaagtg atgaactatt ttgttatagc agaccctgat aaatgcatag gatgtagaac
     7621 ttgtatgata ggatgtgtag ttgcacattc agatgaagat attttttacc aaaatccaga
     7681 tgaaataaat tttaatccaa aactttctgt cataaagaca aaagaagtaa gtgctccaat
     7741 acagtgtaga cattgtgaag atgctccttg tgcaaaggca tgtccaaatg gtggtatagt
     7801 tagggttggt aacacaataa aaataaatga agaaaattgt ataggatgta agacttgtat
     7861 gttagcatgt cctataggtg caatagacat agttacatta aaagatgtag atgaaggaaa
     7921 gctttgcttt agagaaagaa tgacagcaaa taagtgtgat ttttgtatag aatcgccaga
     7981 agggcctgca tgtgtaaatg tttgtccaac taaggcattt actatagtta aggatgagga
     8041 tatagatagt aaagttaaaa ataagagaaa attagctata ttgtaatata aaaaagatgg
     8101 agttttattt atgattaaaa gctccatctt ttttattata atatttatat atctaaaaat
     8161 caattattgc attagtttat ctaatctttc tttattcaat tttttcattc ctatagaagt
     8221 tataataagt aaagtatagg caattataac tgataaaatt ataatagacc aagaaaatct
     8281 gtatccaaaa ttatcaacta acaatccaaa taatgttgaa cctaatgcaa atcccactgc
     8341 aaaaattaat tgtacgattc catatatgct accaaactcc ttttgaccaa agaaagagcc
     8401 agttaaataa gcaggaccaa tcatataagc aaatacagaa agacctttca aaatggcaaa
     8461 tacaaatgca aaagtagaag atttatctac caatagtaat gataaagttg ctataagaac
     8521 caatacaaaa gatataataa gtggctttgt ttgaccgaat ttatcaaaca ataatcctcc
     8581 aaataaatta ccaatgagag caaataaggc aaatgtggag cctactgttc ctattagaat
     8641 aggatttaga taatttctaa gataagttgg atattgtacg gataatgatg aaacatatat
     8701 accaacaaat ataaatccaa tagtcataat ccaaaaatat ttaatttttt tagcttcttt
     8761 taatgtataa ccccatactg aaggagaaat tgtatcagat gctttctctt ttttaccttt
     8821 agattttacc ttttcattaa tatctttagg catcctgagt atgaataata ttacaggtat
     8881 accaactatt aatgctataa ttccaaatat tagataagaa cgactgtatc cttgagttgc
     8941 taataagcga actgcaagtg gttgtagaaa tatactacca atagaaccac cagcaaaagc
     9001 aaagcccaaa gcttttcctt tgctttcttc atcaaaccaa gcacttatta aaacaggtat
     9061 tcctatagca gatataattg tagcgccaat ttgaacaata catgatacag tgtaaaattg
     9121 ccatagttca gtacatatag aaaaagtagc aaaagcaata ctagaaatta tacaacctaa
     9181 taaatatagt atcttaatat tgactttaga aaataataca cctataaaag gtgatgcaat
     9241 tgctgaggca atagtaccaa tagtgaatat tagagaaaaa gaagctaaac taaagccttc
     9301 tccttctaca acataactta taaattgagg ctgtatactt gctacaatac taaatggaac
     9361 agcttgtatc aacatacaac caagtactat aacccaagca tttgaaaagt ttttaatgct
     9421 aaatttattg tttagtaatg tattcatggt atctctcctt taggttatga tttgtagata
     9481 ttaatctaat tattctaatt ttatatatta gttttggata gcctaactat ttaaatataa
     9541 tttgggtatt aatataaaaa ttaactataa aaattgatta ttttaaatgt atggggtaaa
     9601 ttaaagtata taaataaatg aaaggatgga taaaatgtca tttgaaaaaa taaataataa
     9661 taacctagat aaaatacaca acaggaagtg tattatgctt gtaaacttta ataaaaaaga
     9721 attatcatta attaaaaacg taagtaactt tgctggaata agagaccata tcatcttaag
     9781 tgataaaaat ggagagaata taataagaga cattttagat ggaaatatat caaatgaatg
     9841 tgaaaatggg attaagagta agtctgtaat atttaataac actccaagca cacaagtaaa
     9901 tgcattttta gaagggctaa aaaaagtgag aataaataga ccttttacag ctatggtaac
     9961 agagacatct attgattgga cattgaataa tttaatagaa aatttagttc aagaacgtaa
    10021 tgctatgtct ttaggaaaaa caattgaaca taagtaaatt taagatatct tatagtaatt
    10081 ttaactaatg tacattgagt atcatattat attttagaat ataaaatttt aaatgtgggt
    10141 agatggagga gatttgagat gaaagtttta tttacaataa attatggaaa agaaaaattt
    10201 gataaaataa gagaattagg ctatgatgtc atacattact ctgaagatag tattgaaaat
    10261 aatgaggatg taaatacagc agatgtacta gttacataca atccatttga gagattagat
    10321 atttctaaga tgaaaaattt acaatatata cagacaacta gtgtaggtat agaccaactt
    10381 ccaaaagaag aggtattgaa gagaaatatt aagatagcta ataatagagg cggatatagt
    10441 gtacctattg gtgaaagtat tgtattgtat attttagaaa tatataaaaa tagtgcaaaa
    10501 ttttttaaac aacaacaaaa taaagaatgg aagatggatt tttctgtatc agaattgtat
    10561 ggacaaagag ttggattttt aggaacaggt actatatctt cagaagcagc aaaaagatta
    10621 aaagcttttg gtgtagaaat atggggtgtc aatactgatg gaagtagtaa aaaatacttt
    10681 gataagtgtt ttgctactga ggatatgaat attgtatttg aagaatgtga tatagtagtt
    10741 gtagcaatgc cttctacaaa aagtacagat ggaatagtaa acaaagatat gtttaaactt
    10801 atgaaagatg gttctgtatt tataaatgta ggtagaggaa atacagttaa tcagaaagat
    10861 ttagaagaat gtgtagagaa atttagaggg gtagcattag acgtatttga aagtgaacct
    10921 ttaaacaagg acaataagtt gtgggagtgc gaaaatgtca tagtaactcc tcataattct
    10981 tgggtgtcag ataaaaacaa agagagaaca tttaatatgg tttataataa tttgaaacac
    11041 tatataatgg agaataaacc tgtagataat gttgtagaca tatcaagagg ctattaaaaa
    11101 taaaaaattt tgataaaaat aaaaactctt attagtcgta ttaaagatac taataagagt
    11161 tttttttgta ataaatttaa agcccaaaaa gtgatatact aaaaaatata taaataggag
    11221 ataattaatt atagggaaat ttcaaaataa tttaatttta aaaatatgaa gaggtgcaaa
    11281 aagtgagcgt aaaagatgaa attaataaac ttatagagac aataaactac cataatgaaa
    11341 ggtattataa tcaagatagc ccagaaatat cagattatga atacgataag ttaatgaagg
    11401 agttaatttc tttagaagaa gaacatccag aactaaagag aattgattct ccaacaaata
    11461 gggtaggagg taagccatta gataagttca atcaaattgt acataaaact cctatgttga
    11521 gtttatcaaa tgctttttca gagcaagatt tgagagattt tgataagaga gttcaagaat
    11581 atgtgggaga aaatgttgaa tatgttgttg aatttaaaat agatggtctt tctgtaggtc
    11641 taacttataa caatggagag tttgaaaaag gagcaactag aggagatgga gttgtaggag
    11701 aagatatttc tcaaaattta atgacagtaa aaagcatacc tcttaagata aatgataaaa
    11761 aagaactaat agttagagga gaagtatata tatcaaaaga taattttaga aaagtaaatg
    11821 aacaacaaga agaacaagaa cagccattat ttgctaatcc aaggaatctt gcagctggtt
    11881 cattgagaca attagaccca aaactaacag caaagagacc attagatata tttgtattta
    11941 atatggaaaa tatagaagaa tacgatttag aaagtcacag tgaatcacta gagtacttag
    12001 aaaaactagg attttcagta agtcagagtt ataaagtttg taaaagtata gatgaagtta
    12061 ttgagcatat tgaatactgg acagataaca ggggtaattt agactacgaa atagatggta
    12121 tggtaataaa agtaaacaat ataaaacaaa gagacgaaat gggatataca gccaaaagtc
    12181 ctagatgggc aattgcatat aaattcccag cagaaaagaa gaaaactaaa atagtagata
    12241 taatagtaga agttgggaga actggtacaa taacaccttc agcaattctt gaaccagtca
    12301 gacttgcagg tactactgta agtagagcta cacttcacaa tgaagattat ataagagaaa
    12361 aagatataaa aataaatgat acagtattag ttcaaaaagc aggggacata atacctcaag
    12421 ttttagaagt tataaaagaa gaacgtactg gagatgaaat agattttaaa atgccagaaa
    12481 agtgtccagt ttgttcagag ccaacaataa gattagaagg agaagctgct gtaaaatgta
    12541 tcaatatgtc ttgcccagcc caaataagaa ggggaattat acactttgtg tcaagggatg
    12601 caatgaatat agatggatta ggagaatcta taattacact gctattaaat gaaaaaatta
    12661 ttcaagatgt atctgattta tattatataa aaaaggaaga tgtagtcgac ctagagagaa
    12721 tgggcgaaaa atctgctgac aatttaataa attcaattga aaaatcaaaa gaaaatgatt
    12781 tatggagact tataaatgga ttaggtatta aatttatagg agttaaagca gctaagatac
    12841 ttgcatataa ctttaaggat ttagatgaag taatttctgc aactagtgag caactagaag
    12901 aattagagga atttggaagt ataatggcaa acagcgttgt cgagtttttt aaggaagaca
    12961 aaaatatgaa cgttataaac aagttaaaaa atgtaggagt aaatacaaaa tcattggata
    13021 atacaggtga aaaagtagaa aaaatatttg aagggatgaa aatcgtattg actggtacac
    13081 ttcctacatt aaaaagaaat gatgcaaaag aaatgataga aaaaagaggt ggaaaagcta
    13141 catctagtgt tagtaaatcg acaacatttg ttttggcagg tgaagaagct ggttctaaac
    13201 ttactaaagc aaatgattta ggaattaaag ttatagatga agagagattt ttagaattat
    13261 taaagttatc atcgaaagat gaagtaaaag ctgtattaga gagttaaaaa gtcgcttaat
    13321 ttagtagaaa actactataa ttaatgatag aatagttcag taagctaata agattacgaa
    13381 aaatgacaat aattaatatt tgacaaaatt aaaaattata aaaataaatt tataaaaaat
    13441 aaaaaatatg agaaaggata taaaaaatga ccagaagtta tgatagaagt aatgaacaga
    13501 taagacctgt aaagataact agagattata caaagtatgc agaaggttct gttcttatag
    13561 aaatgggaga gacaaaggtt atatgcactg catcagtgga agaaaaagtt cctccttttt
    13621 taagaaatag tggtactgga tggataaatg ctgaatattc tatgctacca agagcaacac
    13681 aacaaagaaa gataagagat gcatctaggg gaaaaattga tggaagaaca caagaaatac
    13741 agaggttaat aggaagagca ataaggtctg ttgtagactt gaataaatta ggagaaagaa
    13801 ctatttgggt agattgtgat gtgattcagg cagatggtgg aactagaact gcatctataa
    13861 caggggcatt tgtagcagtt gcagaagcaa tatataaatt atataaagca aagataataa
    13921 aagagatgcc aataacaaat tttgtgtctg caattagtgt tggtattgta aatggaatac
    13981 acatgctaga tttatgttat gaagaagatt ctaaagcaca ggtagatatg aatataataa
    14041 tgactgataa gtgtgagttt gtagaagtac aggggacagg agaagagaaa cctttttcga
    14101 gagcagattt aaatttattg ttagagttag gtgaaaaagg gaataaagaa ttaataaggc
    14161 ttcaaagaga agctttaggt gaaatatcag atgagatatt gggtatggat tatggtaatg
    14221 aagtagtgat tgctactaat aatgctcata agctagaaga aataggtgaa atcttaaaag
    14281 attttgaata taaagtgtac tctttaaaag atgttgattt agcaggtata gagatagtag
    14341 aagatggaaa aacatttgag cataatgcgt tgataaaagc tagaacaata gcaaaaaaga
    14401 ctaaacttat agcaatatca gatgattctg gcttagaagt agatgcttta ggcaaaaaac
    14461 ctggtgttta ttcagctaga tatgcaggag aacatgcaac agatgaagaa aatagaaaaa
    14521 aactgttaaa agctatgcaa aatgtaccaa tgagcaaaag aaatgcaaga ttcgtctctg
    14581 caatagcagt agtttttcct gatggaaaag aatttgtagt aagaggaatt tgtgaaggaa
    14641 tgataggatt tgaagaaaaa ggtaaaaatg gttttggata tgatagctta tttatagtaa
    14701 aaggatatga taagactttt ggtgaaatac ctagtgttat aaaaaattca atcagtcata
    14761 gagcaaacgc actaaaactt atgaaacaag agtttataaa aagggtagtg aagtaatgaa
    14821 aataggcata gtaagcgaca cacatatgat gattaaaaat atggaaaaaa caataccata
    14881 tttgaaagaa tgtgacctaa taattcatgc aggagataac tttactgatt caagatatat
    14941 tcatagcatg actaatgtag gtattattgc agttaaaggt aattgtgact ttgatgctgt
    15001 tgaggaagaa gttgtctttg aagtggcaaa taaaaccata ttcttatgcc atggagataa
    15061 gtatggtgta aaatatggaa ctaatatgtt agaaaaaaag gcaactgaag ttgatgctga
    15121 tatagttata tttggccata cccatacccc atttagagaa attaaagatg gtgtacttta
    15181 cataaatcct ggaagcactt cacttccaag aggagtatcg tataaaagtt ttgtcattat
    15241 ggatatagaa gaagatgaca taaaaattga agaaatacgc atataaaggt gtatttatct
    15301 aaaaaaatgg caaaaaacgc tcaaaaaatt aaattttatc aaataagtac aacgatatta
    15361 atggaacact tgtaaataaa aaaacttatg tgatataatt aagtggttga attataaata
    15421 gaatgaatta taataccgtt atcgggtatt acataaatat cactaggagg attagaagga
    15481 tgaaagcaga actaattaaa aaagagggta ataaagttac tttaaaaata acagtagata
    15541 acaataaatt tgaagcagca gtaaataagg cttataataa aagcagaaat aaatacaata
    15601 tacctggatt tagaaaaggt aaagctccaa gaattgttat agagactcaa tatggaaaag
    15661 gtatattcta caatgatgct atagaaatat tattcccaga agtttatcca gaagctatca
    15721 aggaattaga catagaccca atagacaatc cagatttaga tatagaagaa ataagtaaag
    15781 acaatgggtt ggttatggtt cttaatgtag aagttaaacc agagtttgaa ttaggaaact
    15841 acaagggtat agaaatagct aaggttgaga atactgtaag tgacgaaaat gttgatgcta
    15901 aactacaaga aatggttgaa aaaaatgcca gattagtaag tgtagaagac aaagctttag
    15961 aagatggaga tacagctata atagacttcg aaggttttga aaatggtgta gcttttgatg
    16021 gtggtaaagg tgaaaattat aacttagtta taggttcaaa cacatttata ccaggatttg
    16081 aagaacaatt agtaggtaaa aaagctggtg aagaagtaga agttaatgtt actttcccag
    16141 aagaatatca ctcacaagat ttagctggaa aaccagttgt atttaatgta aaaataaatg
    16201 atgtaaaagt aaaagaatta tctgcacttg atgatgaatt tgctaaagat actagtgaat
    16261 ttgattcttt agatgaatta aaagcagatg taagagctaa gttagaagaa gaagctaaaa
    16321 atagagcaga tgcagaaact agaaattcag tagtagaaaa agttgctgaa aatacagaaa
    16381 tagaaatacc agaagttatg atacaacatc aaatagataa tatgttaaat gaacttaact
    16441 accaattaca atatcaagga tttggattac aacaattact agagatgact ggtagaacta
    16501 tggaagaatt aagagaagag agaaaagaag atgctaaaaa attagttaag tcttctttag
    16561 tattagaagc aataactaaa gctgaaggaa ttgaagcaac agaagaagaa tttaaggctg
    16621 agttagaaaa aatggcttct gcttacaata tggaagtaga aaaaatagaa gcttctttaa
    16681 gagatgctga caaagaagat ataaaaggtc aaataaaaat aagaaaaaca atagatttat
    16741 tagttgataa tgcaacaata gcttaataaa ataaacgcta actaatatag ttgacgttat
    16801 gaaatgttta gtatataatg atgtgcaaat ataatttagt taaatgcgta taataattta
    16861 cagtagctta aaaaaagcta ctgtaaatta tatagaataa agggggtatg aaaccatggc
    16921 attagtacct gtagttgttg aacaaacagg aagaggagaa agatcttatg atattttttc
    16981 tagactatta aaagacagaa taatcttctt aggagatcaa gttaacgatg ccacagcagg
    17041 gcttatagta gcacagctat tatttttaga agctgaagac ccagacaaag atatacattt
    17101 atatataaat tctccaggag gaagtataac ttctggaatg gctatatatg atactatgca
    17161 atacatcaaa ccagatgtaa gtactatatg tataggtatg gctgcttcta tgggagcatt
    17221 cttgttggca gcaggagcaa aaggaaaaag actagcacta ccaaatagtg aaataatgat
    17281 acatcaacca ttaggtggag ctcaaggtca agcaacagat atagaaattc atgcaaagag
    17341 aattttaaaa ataaaagaaa ctttaaatga gatattatct gaaagaactg gtcagccatt
    17401 agaaaaaatt aaaatggata ctgaacgtga taacttcatg agtgcactag aagccaaaga
    17461 atatggttta atagatgaag tatttacaaa gagaccgtag atagagagag gtgttaatat
    17521 gtctaaatat gaagaaaaac gacaattaaa gtgttcattc tgcggtaaaa atcaagatca
    17581 agtaagaaga ttaattgcag gtccaaatgt atatatttgt gacgagtgtg ttgaactttg
    17641 tgacgaaatt attcaagaag agatagaaga tactatagat gaggatacta catctttacc
    17701 aaaaccaaag gaaatgatgg agattctaaa tgattatgta ataggtcaag aaaaagctaa
    17761 aaaagcttta tcagttgcgg tttataatca ttataagaga atatacagta aaaaatctag
    17821 tagtaaggat atagaaattc aaaagagtaa tatactttta ttaggaccta caggttctgg
    17881 aaagacatta cttgctcaaa ctctagcaag aactctaaat gtaccttttg caatggcaga
    17941 tgctacatca ttgactgaag ctggatatgt tggagaagac gttgaaaata tacttttaaa
    18001 acttattcaa gctgctgatt ttgatataga aaaagctgaa agaggtataa tatatataga
    18061 tgagatagat aagattgcaa gaaaatctga aaacccatct ataactagag atgttagtgg
    18121 tgaaggtgtt caacaagcac ttctaaaaat attagaaggt actgttgcaa atgttccacc
    18181 acaaggagga agaaaacatc ctcatcaaga atttttaaag atagatacta ctaatgtatt
    18241 atttatatta ggtggagctt ttgatggatt agagaagata attcaaaaac gtggtggaga
    18301 taaaacacta ggttttggag ctaaaataga aagtaaaaaa gaattagatt tagggaagct
    18361 atatgaaaaa gtacttccag aggatttatt aaaatatggt ataataccag agtttatagg
    18421 aagaatacca gttttagcta ctttagagtt gttggatgaa gatgcattaa tgcagatatt
    18481 acaggaacct aaaaatgctc tagtaaaaca gtataaaaag ttattggagt tagatgatgt
    18541 tgagctagaa tttgaagaag gtgctcttcg tgcaatcgct aaaaaggcca tagaaagaaa
    18601 tacaggagct agaggactta gaagtatagt tgaaagcgta atgatggaaa ctatgtttga
    18661 agtaccatct agagataata taaagaaggt tatagtaaca gagaaatctg tgaacgaaga
    18721 ctcagtaaat cctatcatag tacttaagga tcaagaggaa agtgcataag atgatgaaaa
    18781 ggagctttaa aagctccttt ttttatgtta atatgctaaa tataaaatag gtatcattat
    18841 tataaaaatg tgagtaatat acctagaata ccaaagacga atacaattgc aatggaacca
    18901 atttttcctt tatataaaag ataaaatgat gctataaatg caattattcc atataaatcc
    18961 caattaactt ctttggcaga tgaaaaagct gctgataata tgaatcctag agtaattggt
    19021 ctaagaactg tcaataagtt ttctaccttt ttattatttt taaatttaga aaataacttt
    19081 gatataatag ttagacctat taatgcaaaa attgtaacac caatagttgc agctagagaa
    19141 ccaaagaagc cagcagtctt aaatcctaca aatgtagcac tatttattgc tacaggacct
    19201 ggtgtagatt gtgatatagc aagtaaatcc aaaaactctt gattagttat aaagtgatat
    19261 ttagatataa attcttgctg gataaatggt agcatggcat aaccgccacc aaaactaaat
    19321 gcccctattt taaggaatat taagaagagt agtattattt ctgacataga ctatatacac
    19381 ctcctccaat tattaaataa atagggctta tattgaatac accaacagat aaaactgcta
    19441 taattaatag tagtatgtta gttttagact ttggtagttt cttgaacatg ctcgtaaaag
    19501 aatacaatat aagagctatt acaacaggcg caactccttt aaaaaatcca tctaaaattt
    19561 tagatgatga atttttaaag tatagatacg ataagactaa gactatacaa aatgatggta
    19621 aagcagagcc taaggtacat ataagaactc ctggtatacc ataaagttta tatcctaata
    19681 atacagatat attaactgcc agtactccag gataactttg agctatggat aaataatcaa
    19741 taaattcttc ctgctctaaa agtttttgtt tgtttacaag ttcatcttgt ataagaggaa
    19801 ccatagcgta tccaccacca aatgtaaacg caccaatttt taaaaaggtt aaaaacaatt
    19861 tcaacataat agaaacctcc aaaagataaa taacatctaa gtatactaat attaatatta
    19921 tatcataata aaaagataat atagtatgat agtattctaa gaatttatca ttaatgttga
    19981 aaattaactt gttcaaatat ataatattaa aagcaaagca attagactag aaaaggagta
    20041 atgttgatgg aacaaaatta tactaaaata gatcatgaat taccattaat tcctctaaga
    20101 ggattagcta tatttccata tatgatatta aattttgata taggtagaga gatatctctt
    20161 aaagctttag accaagctat gatggatgaa gaacttatat ttttaacttc tcagaaagaa
    20221 gcagaggtag atgagccagg agaagaggat ttttatcatg tgggaacaat ctgtaaagtt
    20281 aagcaaatga taaaattacc aggagataca gttcgtgttt tggttgaagg tgtatcaagg
    20341 ggtagagtaa agaaaataga acaagaagat gggtatttca gagcagtaat agaagaaata
    20401 gtatttgata gtgataattt ggatagtgaa acagaagttg aaattgaagc atttgtaaga
    20461 aatgtatttg atgcctttga agagtatata aatattggaa atagggtatc accagaaata
    20521 ttaatatctt tagctgatat agaagatgta gatagattta tagatacgat agctgcaaac
    20581 atatatctaa aatcaagcca aaaacaagaa atattagaag aatttgatat tagaaaaaga
    20641 cttgaactta tttattctat attattagag gaaatagata tattaaaaat agaaaagaaa
    20701 ataactttaa gagtaaaaaa acagatgaat aaggttcaaa aagaatatta tcttagagaa
    20761 caattaaaag ctatacagaa agaattaggt gaagaagaag atataaactc tgaagcagat
    20821 gagtatagag aaaagcttaa aaaaataaaa gcacctaaga caactaaaga gaaaatagaa
    20881 aaagagatag ataaattttc aaaaatatct tctatgtctc ctgatgtatc tgtaagtaga
    20941 aactatttag atactatatt ctcattgcca tggaataaag agacaaaaga taaattagat
    21001 ataactaagg caaaagatat attagatgaa gaccattatg gattagaaaa agtgaaggag
    21061 agaatactag agtatctagc tataagaact cttgctaagt cacttaaagg tcctataata
    21121 tgtctagttg gtcctccagg aacaggaaag acatctatag taaaatcaat cgccagagca
    21181 ttaaatagaa aatttgtaag aatatctttg ggtggagtta gagatgaagc agaaataaga
    21241 ggtcatagaa gaacttatgt aggttcaatt ccaggaagaa taattaatgg ggtaaaagaa
    21301 gcccaaacaa aaaatcctgt attcttattt gatgagatag ataagatggc agcagattat
    21361 aaaggtgacc cagcttcagc aatgctagaa gtattagacc cagagcaaaa taaggatttt
    21421 gtggaccatt acttagaaat accttttgat ttatcaaaaa tactatttgt tacaacagca
    21481 aatagtctag gtaatatacc aagaccatta ttagatagaa tggaagtaat agaagtatct
    21541 ggatatatag aagaagaaaa attaaatata gcaaaaaaat acctacttcc aaaacagatt
    21601 aaagaacatg ctttaaaaga aaactttata aaaatagatg atgaaacttt aagaagcata
    21661 atcaaccatt atacaagaga agctggtgta agaacactag aaagaactat tggtaagatt
    21721 tgtagaaagg ttgccaaaaa atacgttgaa gacccaactc ttgaagaggt tgttataaat
    21781 aagtctgacc tagagacata tcttggaaaa gacatgttta agtatcaact tgcagaagtt
    21841 aaccctcaaa taggattagt aaatggtctt gcgtggacag aagttggtgg agttacactt
    21901 gaagtagaag taaacgtact taaaggtaaa ggcgaaattg tattaactgg aaaattagga
    21961 gatgttatga aggaatctgc gaagacaggt atctcttata taaggtcaat agtggacaag
    22021 tttgatatag accctgaatt ttataagacg aatgatattc atatacacat tccagaaggt
    22081 gctgttccaa aagatggacc atcagctggt ataactatgg ctcttgcagt aatctcagca
    22141 cttactaaaa gacctgtgcc tggaaatata gcaatgacag gagagataac tttaagaggt
    22201 agagtcttag cagtaggagg agttaaagaa aagttattag cagctcatag agctggtata
    22261 acaaaagtat taattcctaa agaatgtgaa gctgatttag atgaaatacc agaaaatgta
    22321 aaagaaaaaa tggagtttgt acttatagaa catatggatg aagtattaga acaagcttta
    22381 ttaaagagtg gtgaaaataa tgaaaattag aagttcagag ataactatga gtgctgtgaa
    22441 taaatcacag tatccagcag aaggaatccc agagatagca ttggctggta ggtcaaatgt
    22501 tggaaaatca tcaataataa atacattgct taacagaaga aactttgcta gaaccagtca
    22561 aacaccagga aaaactagaa ctataaattt ttatctaata aataatgaat tttattttgt
    22621 agaccttcca ggctatggat atgcaaagat agctaagtct gaaaaagaaa agtggggagg
    22681 tataatggaa cgatatctag aaagtagaca agagttatgt tctatattcc tacttgtaga
    22741 tattagacat gagcctacag cagatgataa gcttatgtat gaatggataa agcactttgg
    22801 atataactgt gtagttattg caactaaggc agataaaata tctagaggac aatatcaaaa
    22861 acacataagt ataataagaa aaaaattgca aatggaaagt agtgaaaaag taattcctgt
    22921 ttcttcacta aaaaagactg gtgttgaaga attatgggaa gagattgtaa atcaatacaa
    22981 tcaacatgga tatgaaataa cagtagatta aatttaaaat gttaaatatt gacataagat
    23041 ttatttgaat aataaatgta ataatagtta gttttaatta tattaatatt aaagcaaaat
    23101 ataggatgcc ttaaaatagt tttaatgaac tttttttggc atccttattg tttataaaca
    23161 ataaatatca gtaattttgc taaatactaa taaattttag taaggtatgg gaaaattagt
    23221 ataaattagt tcaactaaaa aattattgac ttatgtagtc agcaataaat agcatttaag
    23281 aaatagattt atctgttttt ctcataaaga aaacagttag tataagccct ataaaacata
    23341 ctgatgctgc aatccaataa gactgattgc tagctataac ataggctgat gtgtgacttt
    23401 taaacttttg attgtatgta agactttgtg caaaaaaact actaaaaaat gctgttccaa
    23461 gagcaaatga taaattacga atagttgcaa gaaaactgcc tccgtatccc tgtttttgag
    23521 gaggaacatc tgctaaaata ctactattgt ttggtgaact aaatgctcct agcccaagtc
    23581 caaaaataac taaacataca attaaaagat acaatggaga atctgctttt aaaagtgcca
    23641 ttccaactag tgagatggtc ataaatgaaa aagatgctgt tagaatgttt tttgcaccgt
    23701 gtttatcaga aagtgaacct gcaataggtg ctataagtac cataataagt ggatgtacag
    23761 tcattacata accagccatc ataggagata aattttttaa ttgttctaaa taaaatggaa
    23821 gtagaaaaga tactgccatt tgaggaaaat aacaagctac tccaatgata ttgcctacag
    23881 taaagtttct atttttaaat agaggtaggt caataaagct ttgttcaaat tttacttctc
    23941 ttaatgccaa caataagaag attataagtg ctgttatacc taaatacaat cttgtattac
    24001 ccttctcatt cattgcaagt aatataagcg tagtgcaaga tgcgaaaagt agaagacctg
    24061 gaatatcaaa gctcttgttt tgttcatcca aaacaggttt aggcagaaat ttaatgccaa
    24121 gaaagactgc tataatacca ataggtatat tgataataaa aatagaaggc catccaaaat
    24181 gttctaaaat tatacctcca attacaggac cactcatatt tcctatacca actacagctc
    24241 cagtgattcc tatagctttt cctttttcat ttgctggaaa tgcattggaa actataccaa
    24301 gcccagtagc cattaaaata cttgctccaa ctgcctgaaa gattcttgaa gaaattaatg
    24361 ttgataaatt gtttgacata ctacacagaa aagaacctat tgtaaatata aaaaatccta
    24421 atgtgtatag acgatttgaa cctactttat cgccaagttt tccgaaaaat aacatagtag
    24481 ctgttacaac aagcatataa gctgttacaa cccactgaat ttgtgacatg ttaattttaa
    24541 agtcagcagc aattgtagga tttgcgatat ttagtatact tccatcaaga gtagacataa
    24601 atacaccaat acagatgata atcaatacta tccatttttg tttcatgata acactccaat
    24661 cttaatagat tttataagta cgatataatt gtaaaataaa caacaaaaaa agcacctgta
    24721 tattaggtac cttgaatgtg tctaatttca tgaataaata cggtagttga aggatttgta
    24781 tagattactc atgtaaaatt acataaaggt actcatatac tattttcttc taccatccag
    24841 attttactgt tggctttgga atatgaccaa attatgccat aaggctcgcg ggcttttacc
    24901 gccgataggg aatttcaccc gtttatgaag aaaaacagat gtattttgta atattatttt
    24961 aacataaaat tataatggaa acaattggat ttaagtaata tccagctgta ttacaataca
    25021 aatatttcaa tatggacact taaattgtat ttatagatag aataaggcac agtatgagaa
    25081 tctataataa ttagataaaa ttaacctgtt attagtatta gatggcaagt tttaaatttg
    25141 tcaaaatcag aaagctgtaa taaaattctt ataatatgaa tatcttaatt aagagatatt
    25201 gtaaattatg aggaggcgct aatatggaag gaaaggtaaa gaaggcattc ccgggtggaa
    25261 atacatcaca aggctcatat tctttttttg actatataat tcctgaaaat gtaaaaagag
    25321 ttttttgttt aaagggtgga cctggagtag gaaaatcctc acttatgaaa aaaatttata
    25381 aagagttttt gcatagagga tatgatattg atttatatca ttgtccttct gacccaagtt
    25441 cgttggatgg tttagttata aagaaattag gcgtggtact tatggatgca actgccccac
    25501 atactatgga cccaaagcta cctggagctt tggatgagat aattaattta ggtgattact
    25561 ggaatacaga agaattagaa aagaataaac aagaaatatc agtttatgat aaagatatta
    25621 gtaattcatt taaaagagca tttaagtttt taaaatcagc agaaccaatc tttagagaca
    25681 tagaagaaaa atattctgat tgtatggatt atggcaaagt aaatttggtc acagaagaat
    25741 ttataaaaag gctatttgat ggagttaaaa gcacaggaaa tctaaaaaga gaaaagcatt
    25801 tatttggttc agctataact cctgtagggt gtttagatta tacagaaaac attttaaaag
    25861 atgtaaagaa agtctattat ttagatggag aaataggaac tgggaaaact acattattaa
    25921 acaaagtata taagaaagct attgaaaaag gtttaaatgt agaagtttat cattatccac
    25981 ttattccaga gaaaattgaa actgtactat taactgattt agatataggc ataactataa
    26041 gtacgacttt taaagaagaa gatacaattg atttaaatca gtttttaaat agagaaaaac
    26101 tacttaaata tgaagaagat attaaatttg atgaaaaagt tttagatgat ttaatttgtt
    26161 gggcagtact aaatcttaag agagccaagt ctaaacatga tattatagaa agttactata
    26221 gtcctaatat gagatttgat gaagtaggga aattaagaga taaattaatt aaaagaattt
    26281 taaaatatga ggaaaactta taaacgtata tgtttaaaat taacgttagt aataatataa
    26341 tttttagtaa attggtgtag ctttgaggct atgccatttt actttttttg ctaaaaaatg
    26401 atattaataa tctccaaagt cattatttgt ttttcataat tattatttcc tttcctaatt
    26461 tatgtttttt tataatatca aaacaatgtt tattgaaagt ttatataatt ttaagaacat
    26521 ctaaaaatgc atacttgata ttggtaaatt agtgatagga gttcaatgta tgatattata
    26581 tactaaagat gaattttaat atataacttt gatataataa gcatatgtaa atgtttaata
    26641 tttaattaaa gaaaattatc atataaaaat aaatttgtaa ggagcaatac agtatgaaaa
    26701 aacaatatgt gtttataata ctagcaagta ctattttagg tatacttgtt ggaaccatat
    26761 ttagagatta tagcaatgaa gaaacagttt atacaagcaa agacaagtca ataagaaaag
    26821 aaataaaaat gacaagaaaa tctataaaag aattaaccaa agagaaagac aagttagata
    26881 aagaaattaa ttcaatgaaa caaaatcaaa aaaattctga agaaatatca gaaatagaaa
    26941 cacttagaga tagtctatca tattcagatg taaagggtag tgggataata ttaagtatag
    27001 atgctataga tgaaaaaaca gggaatatag ctaatagtat agactataat aagattcttg
    27061 taaaagttat aaatgaatta aaagtaaacg gaggaaaata catagaaata aatggtcaaa
    27121 gaattaatca atattcagaa gttgtacttg caggaagcca tataaatata aatggagttc
    27181 ctgtagcaca accatatgaa ataaagtgca ttggagataa ggagaaacta tctaattatg
    27241 tagataaagg tagtaaatat ttagatagca tacaaaccaa ttatccaatg aaaataagca
    27301 taaaaactga agaaaatatc tctatgaaaa aaatgaatat acctaataaa ttaaagtata
    27361 taaagggtga ttaagattat attagaggaa agcagtttgc caatgttaat accagaaaaa
    27421 cttgcaaaaa aatataatgt atttccagtt gagtttcaag atgataattt agttgtagaa
    27481 atagaagatg aggatattta tgctctacag gacttgagat tagctacagg taaagaaatt
    27541 atattgaaga aggagaaaaa agaacttata agtgaaaaga ttgaaaaata ttataatagc
    27601 tttgaacttg atgaggatta tgcaaaaaaa ttatttgaaa atcttttaga aaaagctata
    27661 aaagaaaacg caagtgatat acatatagaa ccatttaaag aacatttaat agtgagaatg
    27721 agggtagatg gagaactaaa ggaagtatca aagtttttag ttgatgtcta tccatcattg
    27781 tctacggtta taaaattaaa ggcatcaatg gatataacag aaaaaaggct tcctcaggat
    27841 ggtagggtgg atataaagtt aggtggaaat ttaattgaca ttagagtttc atcaatacca
    27901 actgtctatg gtgaaaaaat agttttgagg atacttaata gagatacttt tttaaaagac
    27961 aaattagaac ttggtttttc agaggaagct ataaaatcta taaatcgtat aataaataaa
    28021 agagcaggaa tattattagt gacaggtcct acaggtagtg gaaagactac aacagtatat
    28081 tccttattaa atgatttaaa aggaataaat aaaaatatta tgactataga aaatcctgta
    28141 gagtataaga tggatggcat aagtcagatt caagtaaatt caaaagtagg gttgagcttt
    28201 gatgtaggtc ttagagcgat attaagacaa gacccagata taataatggt cggagaaata
    28261 agagatgcag aaacagctaa gatagcagta agagcagcta taacaggtca tttagttata
    28321 agtactttac atactaatga tgcagtatct tccatagcta gattactaga aatgcaaata
    28381 ccaccatatc ttttaaatgc ctctcttata ggtgttatat ctcaaaagtt ggttagaaaa
    28441 gtctgcaatc attgtagcca tgagattatg ataaaagata attttagtgg agatgtaaat
    28501 actaaggtag ctgtagggtg tgaaaaatgt aatgataaag gatactttgg aagaacagca
    28561 atttatgaaa tcttagaaat taatgatgat ataaagacat gtataagaaa tatggaggat
    28621 tctagtacta ttaaagatgt ggcacaaaat aatggaatga taacatttga agatagttgt
    28681 aaaagactaa taaatgaaaa aataacgaca ttagaagagt gtttagtagt aaatgaaatg
    28741 atttaactga attgtatagt taaacttcgt ttggtcagtt gtctttattt aatctatttt
    28801 aattaagatg tttgagtata aattatattt aagtgaaata aaattaaatg cattaaatta
    28861 gaaaatatta agtttattta attgtaatta atataatttg gaaggtatta tagtacatga
    28921 gattatctaa aaatatattt tataatttag aaaagtttta tttagtatta aatagaatca
    28981 gtgataaaga aattagagta atttgcaaag agataggcat attgctggaa tctggatgtg
    29041 aaattacaaa aatatttgaa atcattgaga gtcagtcaag taaaaaagta aagaatttgc
    29101 ttagtatagt atcaaatcat attcaaaaag gtaactcaat agcagaatca tttcaaataa
    29161 caggtatatt ttctaaattc tttataagta tgataaaagc aggagaaact agtggaaact
    29221 tagatataat aatgagtgat ttatctaatt attatgataa agaatacaaa ttaaaaatga
    29281 aaataataac tatttcaata tatccaataa tacttataat attatctatc ttatcaatgt
    29341 tgtttatatt cgtatttgta atacctaatt ttcaggtggt ttttaccaac aatggaattg
    29401 aaccaccttt aataactaga gttttaatgg gaatatctac agtggttaca aataacttag
    29461 cttatataat atttagtttt atattgtttt caataggaag catttatttc tttataacaa
    29521 atgataatat aaaaaaattg attaattcgt taaaattcaa aatacctttt ataaaaaaaa
    29581 ttaatcagtt agtagctaca acaagatttt caagggcatt gtccgtttta attagcagtg
    29641 gaatacaaat tgtggaagct atagacatgt cagctagtgt tatagacaac gaatttattt
    29701 atgaaaggtt aaagatttcc aataattata taaaaaaagg aaatagcata ggtaaatctt
    29761 tgaatttagc aaatattttt ccaaaattat ttatttcaat ggcaaataca ggagaagaaa
    29821 gtgggaaact agataaaagt ctaaatgtaa taaataaatt ttatgaaaat gaattaaata
    29881 acaaaataga gcaaataatg aaatttatag aacctatgct aattgtattt atgggattaa
    29941 ttattggtac ttttatttta gcaatggttg ttcctatgtt tgatgcaatt actaattttt
    30001 agagagaaaa ataaatttta ttagatgaaa cttttgaaaa ggagagaata tttaattgat
    30061 aaatttgata aataaaaaac gaaaaggatt tacacttgtt gaaatgattg tagtagtaac
    30121 tattttaggc gttatatcta gtatagcatt agttaagtat agtaaggttc aagaaagtgc
    30181 caaattaaat gcagactata cgaatgctgc taatatagta accgcagcta gcatggcaat
    30241 taatgatgat gaaaagacaa tagactctct aagtgtagag acattgaagg aaaagggata
    30301 cctaaatact gttccagttc ctcagagtac atcaggtaaa ttcgaacttg tcataaatga
    30361 tagcggaaca gatataagcg taaatataaa ttctaagcaa ttttatccaa aataatattt
    30421 tatattgatt gctgtaagtt ttaaaattat ttttatttaa gaaggagatg gctataatta
    30481 aaaaaattct aaacttagaa ataaatgatg attatataag gcttgtattt ttaagaaaaa
    30541 gtcataaaaa agtttttata gataaatcaa ttataaaaga gattaacttt gatataaaaa
    30601 atgatagtaa ttcgattgag aagattaaat atatagaaga tgtagttaga tttgtaaaag
    30661 aggagattgg taaatcaaaa atattatata aaaatttata ctttaacatt caaattcagg
    30721 atatagtcat tagaaatgtt gaagttctaa atactaagaa aaaaagagac atattaagca
    30781 tgattgaatt tgaaataaca caatacattc caataaacat aaataactat tcaataaaat
    30841 ataaagttat aaattctaaa aatgataaat tgaatataca agtaattctt ttcccaaaga
    30901 gtattattca attaattaag aacatttcag aaaatctaaa tatgaatcca aagactataa
    30961 atataaattt tgatatatta caaaagctta taaacttaaa tttaatagag aatttttcag
    31021 aagaaggggt atttatagaa tgtaaaaaaa gtcagttaat tataaatata acaaaagata
    31081 aaaaaataag agaaacatac ttgctatcaa aagagggaaa atcatatgag ttcataaaaa
    31141 gattattaag ggattttaag tatgtttatt actatggtat agaaaattgt tttattgaag
    31201 aatactttaa atatacagat aaatctattg aagtaaatcc attaagatta aaagataaag
    31261 taaaagtaga aaataatttt gatgcagatt tagaagacaa taggataaat tatataagta
    31321 atataggaat gattatttaa gtgaaagtgg ataaaacgat aaattttctt aatggattta
    31381 aaaaaactaa accatgtaat aaaatctata aaataataat agtcttaatt ttaacgtgta
    31441 ttttatttaa atcatttatg tatgtgaaat ctataaatga acttgaagat tatataagtc
    31501 aaaataagct agtggataaa tcaagacaca ctttaccaac aacagataaa actagagaga
    31561 aattttctaa aataaaactt aatgaaataa aaaaaatata tgaaacaatt ggaataaata
    31621 gtattactaa aatatcgata gataaaaata agctagagat tgaaggtgtg tgtagtgatt
    31681 tagatgtttt aaacaatcta aggaaaataa agtacataaa atattattac atagacagta
    31741 ttgtaagaga tggagaatat tatagattta gaataaaaag ttagatgggt gattattttt
    31801 gagattaaat aatagagaaa aaaatctact taaaatattg ttaatattag ttattatatt
    31861 ggcaagtgat atagcagtaa gttatttgga agaaaactta actagtttga agaatgaaaa
    31921 gcaaaatata ataaataaaa taaataatca agataattat caaataaagg ataataagca
    31981 tatagatgat aaatatatag aaagtgttga atcaaataaa aatgaagaat taaaaaataa
    32041 ttttaataac tcatttttag ataaaaaaac aaataaagat atagtgttat tagtagaaaa
    32101 tgaactgaga gatattgtga atgtagaata tattaatcaa gaaagtagtt tagataatca
    32161 caataaaaaa caagttaatt tagaaataaa agttaatgga gaacttgcaa atttgttgaa
    32221 acttgaaggt gtaatgaaga agttaagact aaataataaa cttgaaaaga tagaaattaa
    32281 caaattaaaa gtcaataatt ttgatgttca aaatattcca aatgaatata aacaagaaaa
    32341 agacaatatt gttgaatgta aaatgacagt tagagtcata taacaaaaaa gaatagataa
    32401 agtaaaaaac tattatcaat taataaaatt ttatagagga attagtttta cgataattca
    32461 tttctacaag agggattgtt gatgatttta tcgaaatcct aattaaagtt aatatattgt
    32521 accaaaatat aagtgaattt aatagaatat ttacttatac tatagattga ttaataaaaa
    32581 aatggtataa taacaaattg tactttaatt taataataag ggagtggaag tcatattgtt
    32641 agggagaaat gagctatgcc cttgtggaag tggcaaaaaa tacaagaaat gttgtttaaa
    32701 taaagatatt gtttcagaaa gagcatgcag aaaaactgaa ctttcacaaa aacaatatac
    32761 agatttatat tcaaagttat atgattattc aagacaggat aagtttaaag aagaatgtga
    32821 aaaagctaaa gaaatgtttt atataatgca aaatgatagt gtaaatgaaa aatttgaaag
    32881 attttttaat acttatttaa tacaagacca cataatggaa aataaaaagg ttatgacagt
    32941 tggttttctt gaagaaaatg gtgcaaacct aagtcaatca gaagtatcaa tattaaaaag
    33001 tatgtttgaa tcatacgtaa gtatttatga ggtaaaagaa gtttctgctg gaaaaatagt
    33061 attaaaggac tgtttaagtg gaaatgaact ttgtacagaa gatgtaaaac ttctgagaag
    33121 ttttaaaatc ggaagttgta tgatagctag aatagttgat attgaaggaa ctaacatatt
    33181 gatagatata actataagta tatcaaatga ggttaaagat ataattttaa aggatattat
    33241 gaatctattc aatcaatatc aagatgtata caaagatatg aagtcgttct taatttatca
    33301 tacacatata ctatacaagt atatacaaca gcttttagac ccaagtatag ctgaatattt
    33361 aaagagagaa agagataaaa acgatacaaa agttaattca gaaaatgaat tagctgaaga
    33421 agaatgtaaa gttttagata ctcttaaaga aaatgtagaa aaagaaaata tagatgcatg
    33481 tatagagttt tggaatgaat ataagaaaaa tcatgaaaat ataaaaggag ctgaaaatgg
    33541 ttgggcagct gctgttgaat actatgttaa aaaagaagca ggacaaccta taactcaagt
    33601 tcaaatatca aagaaatacg atataagctc tagtacacta ggaaagagat acaaggattt
    33661 aaaaatatct taattaatta taaaaagctt taagtcatag ataaagaatc tatagtataa
    33721 tatatgtata atgtttagaa agaggtatta ataatgagtc ttagtttagg aaatgcaatt
    33781 gctgtatcaa cgaactttat aaaatctaac ccagctgtac ctgtgtacaa cggagaagaa
    33841 atatatgcag ttatttatca tatagaaata ggatataata atggtgtatc acctgatacc
    33901 aaacaatata taataataga ctataaagag tttgatttat ctatggataa aaaaaatgaa
    33961 ctaataaata ttgctaaaga gtactgtaaa tctaaaggta ttgtagaaaa cgaaaacctt
    34021 gaaataaacc ttttagacaa tgaagaagca gagaacttct tagaaaaggt gtttaataat
    34081 atgaaggtta taagaggcct tataactaaa aaaggataaa taaatggact atataggaat
    34141 agaaaatata acaccttatg aaaatacata tgaatttagt gtatatgaat atgatgatga
    34201 aatcacctta ggtagtgaaa agttatatgt atgtgaatta agggttgtat tgattaaagt
    34261 taattctctg tatgttgaaa gattgcataa atcagttgaa gcaatggtct tagtaaaaaa
    34321 cttgaaaaaa gatttagata aaacacttgt tgtaaacaaa ataaagaatt ttgtgctaga
    34381 tgagatttgg gtagaaaatc tagtaaaaga gaatatagaa gttatatttg tagaaagcta
    34441 ggaataaccc tagctttttt atattacaat ctaagagagg aaaacaatat gttaagagta
    34501 tctaatgtaa aacttggaat tgataaagat atatctttat taaaagatgt tatacttaag
    34561 aagctaaaaa taaaagaaaa aaacttagtc aaatatagta tatataaaga atctatagat
    34621 gctagaaaaa aaggaaaaat ggaatttgtt tattctgtag atgtagaagt taaagatgaa
    34681 aataaaatac ttaactcaaa aataaaagat gtaacaaaaa taaaggaaat cagatacgta
    34741 aatgtacctg tgggtgataa aaaattaaag aataatcctt tggtaattgg tagtggacca
    34801 gctggtttgt ttgcaggtct gcttttagct caaatgggtt atgaaccaat catacttgaa
    34861 agaggtcttg atgtagacag tagaaccaaa gatataagtg atttttggac aactagaaaa
    34921 ttaaaaaata attcaaacgt tcaatttgga gaaggtggag caggaacttt ttcggatggt
    34981 aaacttacaa ctagaataaa agatatacga tgtagaaaag tattagaaga gttagttcag
    35041 tttggagcac cagatgaaat attatactca cataagccac atgttggaac agatatatta
    35101 aaaaatgtag ttaaaaatat aagaaatgaa ataataagtt taggtggtca agttagattt
    35161 aattcaaaag taacagatat agttgtatca aatgattcta tacaatctgt aataataaat
    35221 gatactgaaa aaatagatac agatacaatt atattagctg ttggacatag tgcaagagat
    35281 acttatgaaa tgttgtattc aagaggtata aaaatagttc aaaaaccttt tgcaatagga
    35341 gctagagttg aacatccaca agatttaata aataaagcac agtacaagga tttttataat
    35401 catcctaggt taggagctgc agattataga cttatagagc atgtttcaaa tggaagaaca
    35461 gcatatactt tttgtatgtg tccaggaggt agtgtcatag catctgcatc aaatgatttt
    35521 gaaatagtta caaatggtat gagtgaacat gcaagagata aaataaatgc aaatagtgca
    35581 tttttagtaa atgtaacgcc agaagatttt aagagtgata atccactagc aggtgttcat
    35641 ttccagcaga agtatgaaaa attagctttt gaattaggtg gaaaaaatta taatgcacca
    35701 gttcagcttg ttggagattt tataaacaat aagacttctt tgaatttagg aagtgttgag
    35761 ccatcatata gaccaggata tacacttaca aatttaagtg aatgtttgcc tagcttcgta
    35821 acagagacta tgagagaagc gtttatatct cttgataaaa aattgaatgg gtttgcaatg
    35881 tatgatgctg ttttgacggg agtagaaact aggtcatcat caccaataag aatagtaaga
    35941 gatgaaaata ctttagaatc agtgagtatt aagaatctat atccatgtgg tgaaggtgct
    36001 ggatatgcag gtggtatagt tacagcagca gttgatggta taaaatgtgc agaaaaaata
    36061 atacaaaaat acaccaataa tacaaaaatt taacataaac ttaatgattt tttaatattt
    36121 aacatgaatt taacattatc actcctataa tttgataaaa tacaataggt tataaaattt
    36181 ttagatacag taatctcttt acaaggagga aataatttga acattataat aagtctaatg
    36241 ggtggattag gtctgttctt atatggtatg aaccttatgg gagaaggtct tcaaaaatct
    36301 gctgggacaa agctaaaaaa gataataaaa ctacttacta gtaacctatt tatgggagtt
    36361 ttggtaggta caggagttac agcagtaata caaagttcaa gtgctactac tgtaatggtt
    36421 gttggtttcg taaatgcagg aataatgact ttaaaacagg caataggagt tataatgggt
    36481 gctaatatag ggactactgt tacagcccaa ttggtatctt tcgacttaac tggtatggcc
    36541 ccagtagcat taggtgtagg tattatactt tatttatttg gaaataagcc tagaataaaa
    36601 aatatagccg aaatacttat aggttttggt atattattta caggtatgga ttttatgaag
    36661 atggcagtgg agccactaag agactatcaa ggatttactg acttacttgt tacatttggt
    36721 agatatccac tacttggatt attattggga tttgggatta cagcaataat acaaagttca
    36781 agtgcatcta tgggtatgtt ggttgcactg gcagcagaag gtctagtgcc attatcagca
    36841 gcactgccaa ttctttatgg ccaaaatatt ggtacatgtg taacttcact gttatcaagt
    36901 attggtgcta acaaaaatgc acgaagagca gctatgatgc atctaatctt caatgtttta
    36961 ggaacggtga tattcttaat attcttgaat aaaccagtag taagcatggt tacaagttgg
    37021 gacccaagca atgttgcaag acaaatagct aatacacata cattgtttaa tataatatct
    37081 gtattgatac ttttaccatt tacaaatctt attataaaac tagctataaa gcttgttcct
    37141 gatagagcag gtgatataga tgaagatgaa actaaaacta ttaaatatat agatgataga
    37201 atgatagaaa ctccttctat agctcttgca aatacgataa aagaagcact tcgtatgggt
    37261 gagaaggcga aggaaagcct aaatgcatct atggaagctt tagtagaaca ttcaactgaa
    37321 aaaatagata agacatatag gcgagagaga ttaatcaatg atttacagaa agctatttta
    37381 aattatttac ttaaactttc aaaagcacct ttagatgatg attcaagaga agttgtggat
    37441 actttgttta atacagtcaa tgatatagaa agaattggtg accacgctaa aaatatagct
    37501 gaattatcgc aagttgcaat agattcaaat atttctttct cagaagaagg acaatctgaa
    37561 cttgatgtta tgtataatag agttgtttca gcatatactt atgcattaga atcaatgaga
    37621 actgataatg ttgatttagc ttgtaaggtt ataaaaattg aagaacaagt tgatataatg
    37681 gagaaatctt gtagagctaa tcacatgtat agattgaaca ataatctatg tagtatagaa
    37741 aatggagtta tttatttaga cgtaataagt aatttagaga gaatatctga ccatgctgtc
    37801 aatatagcac aacaagttat agcaaagaga ttaggaaatg attaaaaata attaatttaa
    37861 aataatataa aatttaaaat agaggataaa taaaagagaa actttaaatg atacgtttag
    37921 agtttctttt tttgtaaatt tatttgacta aaatttttaa atttatacat agttatagcg
    37981 tttagaagaa tcgatttcct gataataaat gatgagatat gtatgatttt gtggcaaact
    38041 tttaaaaaaa acacctatat tttgtgttat aatctcttta aaacgaatat gctgaaaaga
    38101 gggatttaaa tgggaaaaat aaattttgat tatagtaaag ctacagagtt tttttgtcaa
    38161 aacgaaatag atgtcatgca accatatgta gatgttgcgc acgacatgtt acataataaa
    38221 actggtttag gaaatacttt tttaggatgg atagaccttc ctaaaaatta tgataaagaa
    38281 gagtttgaca gaataaaaaa atctgctgat aagataaaat cagactcaga tgttcttttg
    38341 gtaataggta taggaggctc ttatttaggt tcgagagctg ctatagatat ggtaagtcat
    38401 tcttttagga atggacttaa aaaagagcaa agaaaggctc cagaagtata ttttgtaggg
    38461 cataatataa gctcaacata tattatggat ttattagata taattgaagg aaaggatatt
    38521 tctgtaaatg taatatctaa atcaggaact actacagaac cagctctggc ttttagaata
    38581 tttaaagatt acttagagaa aaagtatggt aaggaagaag caagaaagag aatttatgca
    38641 acaacagatg caagtaaagg tgcacttaga cagttagcta cagaagaagg atatgagact
    38701 tttgtaatac cagatgatgt aggtggtcgt ttttctgtat tgacagcagt tgggttactt
    38761 cctattgctg ctgctggact tgatattgat gctatgatga aaggcgcaaa tgatgctaga
    38821 gaagcatttc aaaatcctga cttaaaaagt aatgatagtt atagatatgc tgttgctaga
    38881 acaattttac atagaaaagg aaaagatgta gagttattag tgaactatga acctcaacta
    38941 cattatgtaa gtgagtggtg gaaacagctt tatggagaaa gtgaaggaaa agaaaataaa
    39001 ggtttattcc ctgcttctgt agatttctca acagatttac attctatggg tcagtacata
    39061 caagatggaa aaaggctttt atttgagaca gtacttaatg ttgaaaactg taagagaaat
    39121 ataactataa gttcagagga agtagactta gatggtttaa actatttagc aggtaagact
    39181 gtagattttg taaatcataa agcttttgaa ggaactctat tggctcatac agatggaaaa
    39241 gtacctaatt tagtaataaa tatacctcaa ctagatgagt ataattttgg atatttagtt
    39301 tatttctttg agaaggcttg tggaataagt ggatatttat tgggagttaa tccatttgac
    39361 caaccaggag tagaagctta caagaaaaat atgtttgctt tactaggcaa accaggttat
    39421 gaaaaagaaa aggaagagct agaaaaaaga cttaaataat tttaaatagt taaggtttaa
    39481 ttaagattaa aataatataa tgaaatcatc aaaaaggagt ttactcaaaa tagatgattt
    39541 catttttttt atgaaaaatt gggaaaaata tattttgata atttatatta tattaagata
    39601 gggagtggta tgagatgtca agaagaaaga aagggataag tttagtaata ttagttgcta
    39661 taataagttc aatacttagt agttttctaa caataatttt agttaaggac aatttagtaa
    39721 gtaaatctac aggaagttct acgccgatag ttgtaaatga tgatggtaag agtcaaaata
    39781 tttatcaagc agttgcagaa aaagctacgc catctgttgt aggtattaca acaactagtg
    39841 ttgatactag taatatgttt gcaataccaa ctgaaacaca aggtgtagga actggaatca
    39901 tagttgattc aaatggatat atacttacta attctcatgt tatatcagat ggtcaagcta
    39961 caagtgtaaa tgtattattc aatgatggtt caacaacttc aggtaaagta gtatggtttg
    40021 accaacaact tgatttagct atagttaagg ttgataaaac tggactaaca ccagcagaat
    40081 ttgctgatag tgacaaagta aaagttggag atatatcaat agcaataggt aatcctcttg
    40141 gattagattt tcaaaaaaca gttactcaag ggataataag tggattagat agaactatac
    40201 aaacagaaaa aactaatatg actggtttat tacaaactga tgcaagtata aatgcaggaa
    40261 atagtggagg accattgtta aatcaaaaag gtcaagtaat tggtataaac acagcaaaag
    40321 cttctcaagc agaaggatta ggatttgcaa taccaatcaa tacagctaag agtatagttg
    40381 aagaagtaat caaaaatgga aaatatgaaa aagtaacttt aggcataaaa ggtacagatg
    40441 tatcaaatta tgaagcagca acaggtacaa aattaagtac tgataaaggt gtttatgttg
    40501 cagaagtaat atctggttca tcagcagaaa aagctggagt aaaggtaggg gatattataa
    40561 ctaaagtagg agatacagat ataacaggta tgaatgattt aaataaaaag ttgtatactt
    40621 tctcaaaagg tgctagtaca aaaataacag taaatagagg tggaaaagca gtaacaataa
    40681 atgtgaattt ctaaatatga ccagaaagat agagactaca tggtaaagtg tagtctctat
    40741 ttttatttaa tttttatagt atatacatct aaattaatta aa
//
LOCUS       DAEPXW010000030        40069 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.031, whole genome shotgun sequence.
ACCESSION   DAEPXW010000030 DAEPXW010000000
VERSION     DAEPXW010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40069
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.031"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(<1..1388)
                     /locus_tag="KRM55_001519"
     CDS             complement(<1..1388)
                     /locus_tag="KRM55_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH1593768.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKI"
     gene            complement(1399..2619)
                     /locus_tag="KRM55_001520"
     CDS             complement(1399..2619)
                     /locus_tag="KRM55_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBH1593769.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(2633..3421)
                     /locus_tag="KRM55_001521"
     CDS             complement(2633..3421)
                     /locus_tag="KRM55_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1593770.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEEKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEIAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPNPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(3438..4712)
                     /gene="larA"
                     /locus_tag="KRM55_001522"
     CDS             complement(3438..4712)
                     /gene="larA"
                     /locus_tag="KRM55_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBH1593771.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(4830..5543)
                     /locus_tag="KRM55_001523"
     CDS             complement(4830..5543)
                     /locus_tag="KRM55_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH1593772.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            5668..6927
                     /locus_tag="KRM55_001524"
     CDS             5668..6927
                     /locus_tag="KRM55_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBH1593773.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            7207..7773
                     /locus_tag="KRM55_001525"
     CDS             7207..7773
                     /locus_tag="KRM55_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1593774.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(7974..9179)
                     /locus_tag="KRM55_001526"
     CDS             complement(7974..9179)
                     /locus_tag="KRM55_001526"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH1593775.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SVKKLLKID"
     regulatory      complement(9282..9388)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(9480..9848)
                     /locus_tag="KRM55_001527"
     CDS             complement(9480..9848)
                     /locus_tag="KRM55_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBH1593776.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(9900..11177)
                     /gene="obgE"
                     /locus_tag="KRM55_001528"
     CDS             complement(9900..11177)
                     /gene="obgE"
                     /locus_tag="KRM55_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBH1593777.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(11288..11578)
                     /gene="rpmA"
                     /locus_tag="KRM55_001529"
     CDS             complement(11288..11578)
                     /gene="rpmA"
                     /locus_tag="KRM55_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBH1593778.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(11592..11909)
                     /locus_tag="KRM55_001530"
     CDS             complement(11592..11909)
                     /locus_tag="KRM55_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBH1593779.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(11924..12235)
                     /gene="rplU"
                     /locus_tag="KRM55_001531"
     CDS             complement(11924..12235)
                     /gene="rplU"
                     /locus_tag="KRM55_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBH1593780.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(12336..13757)
                     /locus_tag="KRM55_001532"
     CDS             complement(12336..13757)
                     /locus_tag="KRM55_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBH1593781.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(13775..14476)
                     /locus_tag="KRM55_001533"
     CDS             complement(13775..14476)
                     /locus_tag="KRM55_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBH1593782.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPEGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(14478..16322)
                     /locus_tag="KRM55_001534"
     CDS             complement(14478..16322)
                     /locus_tag="KRM55_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBH1593783.1"
                     /translation="MNKIDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILGRLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            16641..17834
                     /locus_tag="KRM55_001535"
     CDS             16641..17834
                     /locus_tag="KRM55_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBH1593784.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEKDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(18046..19128)
                     /locus_tag="KRM55_001536"
     CDS             complement(18046..19128)
                     /locus_tag="KRM55_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1593785.1"
                     /translation="MKKIRKLATKLLIATMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEAVKAQNPTPTVKNPTPAKPSAPV
                     GPGNQTMIADQEGAILNEVYGNNMKPQNKMYEGVPCSSIDSSINTIKFTSSNSNLDPS
                     KHTVYVIGFKKTQYGMVALAPESKPVSYPFEYDKPFSLDFTGKNRSAAELSKYCKKNN
                     IIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(19692..20483)
                     /locus_tag="KRM55_001537"
     CDS             complement(19692..20483)
                     /locus_tag="KRM55_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593786.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(20487..20816)
                     /locus_tag="KRM55_001538"
     CDS             complement(20487..20816)
                     /locus_tag="KRM55_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593787.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(21301..21714)
                     /locus_tag="KRM55_001539"
     CDS             complement(21301..21714)
                     /locus_tag="KRM55_001539"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBH1593788.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(21755..22885)
                     /gene="rodA"
                     /locus_tag="KRM55_001540"
     CDS             complement(21755..22885)
                     /gene="rodA"
                     /locus_tag="KRM55_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBH1593789.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(22970..23254)
                     /gene="minE"
                     /locus_tag="KRM55_001541"
     CDS             complement(22970..23254)
                     /gene="minE"
                     /locus_tag="KRM55_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBH1593790.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(23272..24069)
                     /gene="minD"
                     /locus_tag="KRM55_001542"
     CDS             complement(23272..24069)
                     /gene="minD"
                     /locus_tag="KRM55_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBH1593791.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(24093..24776)
                     /locus_tag="KRM55_001543"
     CDS             complement(24093..24776)
                     /locus_tag="KRM55_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBH1593792.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(24874..27852)
                     /locus_tag="KRM55_001544"
     CDS             complement(24874..27852)
                     /locus_tag="KRM55_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBH1593793.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(27864..28352)
                     /gene="mreD"
                     /locus_tag="KRM55_001545"
     CDS             complement(27864..28352)
                     /gene="mreD"
                     /locus_tag="KRM55_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBH1593794.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAVIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(28367..29260)
                     /gene="mreC"
                     /locus_tag="KRM55_001546"
     CDS             complement(28367..29260)
                     /gene="mreC"
                     /locus_tag="KRM55_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBH1593795.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(29270..30280)
                     /locus_tag="KRM55_001547"
     CDS             complement(29270..30280)
                     /locus_tag="KRM55_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH1593796.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(30401..31060)
                     /gene="radC"
                     /locus_tag="KRM55_001548"
     CDS             complement(30401..31060)
                     /gene="radC"
                     /locus_tag="KRM55_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBH1593797.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(31105..31689)
                     /gene="maf"
                     /locus_tag="KRM55_001549"
     CDS             complement(31105..31689)
                     /gene="maf"
                     /locus_tag="KRM55_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBH1593798.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(31909..32880)
                     /locus_tag="KRM55_001550"
     CDS             complement(31909..32880)
                     /locus_tag="KRM55_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBH1593799.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(32896..33471)
                     /gene="rsxA"
                     /locus_tag="KRM55_001551"
     CDS             complement(32896..33471)
                     /gene="rsxA"
                     /locus_tag="KRM55_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBH1593800.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(33486..34079)
                     /locus_tag="KRM55_001552"
     CDS             complement(33486..34079)
                     /locus_tag="KRM55_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBH1593801.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(34092..34661)
                     /locus_tag="KRM55_001553"
     CDS             complement(34092..34661)
                     /locus_tag="KRM55_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBH1593802.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(34661..35638)
                     /locus_tag="KRM55_001554"
     CDS             complement(34661..35638)
                     /locus_tag="KRM55_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBH1593803.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(35661..36998)
                     /gene="rsxC"
                     /locus_tag="KRM55_001555"
     CDS             complement(35661..36998)
                     /gene="rsxC"
                     /locus_tag="KRM55_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBH1593804.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(37214..38158)
                     /locus_tag="KRM55_001556"
     CDS             complement(37214..38158)
                     /locus_tag="KRM55_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593805.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(38269..39543)
                     /locus_tag="KRM55_001557"
     CDS             complement(38269..39543)
                     /locus_tag="KRM55_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1593806.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNSTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(39675..40046)
                     /locus_tag="KRM55_001558"
     CDS             complement(39675..40046)
                     /locus_tag="KRM55_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1593807.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
BASE COUNT        12336 a         7650 c         4525 g        15558 t
ORIGIN      
        1 tatattttcc ctggatttaa aatattttta gggtcaaaag ctaactttat atttttaatt
       61 aacatcatat aagcatctga atttgattca tgtaagtact cttttttagc atatcctatg
      121 ccatgttcac cagaaacttg accactaagt tctctagatt ttttatacat atagtcaaaa
      181 gtttctttta atcttatttt ccatgtatta tcatccatac catcttttaa aatatatatg
      241 tgtagatttc catctcctgc atgaccaaaa ctttttattc ttatttttaa tttgtcttga
      301 agctcgtgag tgtatcttat aaactctgct atcttatctc ttggaacaac gacatcacat
      361 tcatccattt gtgtcgtaga tgcctttata gcttctaaaa atgcacctct ggctgaccat
      421 atagaatcgt ttctttcttg tgtatctgat ataaatacat ctaatgcacc attttctaaa
      481 cataaattag ctactttttc atattctttt tctatatctt cagtgctatt tccatcaaat
      541 gtaagtaaaa gataagcatc tgatgtatta tctggaaact ttttacctaa aaattcttct
      601 gctgccaata ttacatctct ttccataaat tctatagccg ttggtattga ttttgatttt
      661 attattttag gaacagtttc tattgccatt gataaatctg gaaatggtat aagcaaactt
      721 atacttttct ttggtaaagg aagcaatttt aatatagctt tagtaactat tcctaaagta
      781 ccttctgagc ccactaataa atcctttata ctatatccag aactattttt aaccaccttt
      841 ccacctacat ttataatttc tccatttggt agtacaactt caagtcctct tacataatcc
      901 cttgtaacgc catattttac tgctctcata ccacctgcat tagtgtttat attacctgca
      961 attgtagcac ttttttcacc tgggtcaggt gggtaaaata aatctctatc ttgaacatat
     1021 tgacctattg tcatcaataa aacacctggt tctactgtca atgttaaatt ttcataatca
     1081 acttcaagta ttttattcat tttacataga ttaatcatta ttccaccatt tatggcaaca
     1141 gcagcaccta caagaccagt accttgacct cttggtgtga ctggtatatt atttttatat
     1201 gcgtatttca ttattttaga tacttgttca gtttcaagta catttactaa aacttcaggg
     1261 tacttctcaa tccctccaag ttcatcatgt gaaaaatctt catttatatc acttccaact
     1321 aatacatttt cttctccaca agtatctatt aaaaaatcta tatctttttt atcgattaat
     1381 ttatacattt ctatccccct atttagctgc tgatgccata tatttttgat tattatcttt
     1441 gttattttct attttttcaa tcaatttagg aataatatca taaatatcac ctattaaagc
     1501 taaatgtgct acatcaagta taggcgcttt atcatcttta tttattgcta ctatatagtc
     1561 agcaccctgc atccctgcaa caaattgaac agctccagat acaccacaag ttattatcaa
     1621 tttaggtttt acagttctac cactaagacc tatttgtttt ttagcatcta tccaacctgc
     1681 ttctattaca ggtcttgttc ctgccacttg agcgtttaac ttatcagcta atttatatat
     1741 catctccata tcttcttgtt tttttattgc tctacttgcc acaactatca cttcagcttc
     1801 ttccagacca acttctttat ttttttcttt tacactcagt accttaattt tagattttag
     1861 ttcttttttt tctactttac ataaagttat ctttcctgta gtattctcta ttttttctgg
     1921 tgctgaaaat attttatatc ttacagtggc aaattgtggt ctattattag gtgtgtttat
     1981 atgagccatt atatttccac caaatgctgg tcttatttgg tctaaatcag tatttgattg
     2041 aatatcaagt attgtacaat ctgctgtaag acctgttcta aatctagcgg caagtcttgg
     2101 agctaatgac ctacctaatg tagttccacc aactaatact atcgttggtt ttattttatc
     2161 tataaagttt tctattgctt ttgaatatgg ttctatccta aaatctttaa attcatcttc
     2221 atcatataca aatacttcat ccaccccata agaaatcaaa ttactgcact tatcttttat
     2281 gtcttttcct acaaatacac aatacacagg ttgttttatt tttgatgcca tctcacgagc
     2341 tttacctata agctcgtacg ttacaggatg tatatttcca ttatgatgtt caacatatac
     2401 tgcaattccc ctccattcat ctttattaat ttgtacttta ctactctcta taaattcaaa
     2461 tgcgcctttt ggtccacttt tgacacacaa cttgcacatc ttacagccag cacttatttc
     2521 tactatacct gacttttctt ctatagcccc aaaaggacat atttctaaaa ttctctttaa
     2581 gtcagttatt ttatcttgat ttacaactat ctttgacatt tattactccc ccttacacca
     2641 actttaattc ctctaattta tttacaagtg caaaacttag ttcatctgca tttcctctta
     2701 caatattttt atctgtattt ggatttggag gaaatattct tacaacttga gtaggagaac
     2761 cattaagtcc atagttattt tcatctttat cttcaaagtc atctaagcta tatacaggta
     2821 tttctctatc tttagtatta agttttaatt taaatgaagg tagtcttggt tgaaaaatgt
     2881 ctttttctac agttattaaa catggatatt caatctcaca tacttgtaaa tcatttggca
     2941 tatctatttc aacaactata ctttcatctt taacttcaat taattttgta acgttagtaa
     3001 catgaggtat atctaaaaat tcagctattt caggtcccac ctgtgctgta tcaccatcag
     3061 tagtttgttt tccacaaatt attaggtcta cctttcccat cttcttaata ccttgtgata
     3121 tggtatagga agtagccaat acatctgctc ctccaaatct cctatcactt attaatgctc
     3181 cttcatcagc tcccatcata aaactttctt caattacctt ctttgcctga ggaggaccca
     3241 tgctaagtac ttttagattc gctttcttct cttcctttat tctaagagct gtttctaaag
     3301 catataggtc atagggattc atttttgaat ctactccatc tctttttagt actcctgtag
     3361 tttcatcaac ttctactgaa gtcgttccag gaacttgttt aatacatgtc aaaatttcca
     3421 taaagtacac tcctttttta tttaactata actgatactc catcaggtat aactactact
     3481 ttgctctcct taccaactat actattcgcc atttctaaag cttctttaaa gttaaatgca
     3541 tgtttcatat gcattttttt tatcatttca ggattacact tatctgttac cattatcaca
     3601 gtatatttag ataatattct cgctagtatc tgaaattccc attggtctgg aatcgtatct
     3661 actctatcga cacttctaat tttatctaaa agttgttttg gagaatctgc atttgctaca
     3721 ttttcataaa aagattgacc tccatgacca tcattacatg ctgaaatcat tattattact
     3781 ccaccatctt tacaagtagc ttcagctgct gtcattcctt taacagattg ataaatattt
     3841 tggtctagtg gatatccacc atttgtagtt acaacaatat cagattttat agaatttact
     3901 tttgataact ctgttacaaa tctacatcct ttagtatgtg ctttttcgac atcaccagca
     3961 aaggaagcaa ttattttttt atctttatct attacaacat tcaatatgaa tgctaatttt
     4021 gcaactttag ctgcatatac catatcctca tgaataggat tattattcaa ttttccagtt
     4081 cttgaattat cactatctat gaagtcacta cagtgattgt acattatagt ctttgcagat
     4141 gcgattcctg gaagtacgct ttttctgcca cctgaaaaac ctgcaaagaa atgaggttct
     4201 ataaaacctt ctgctatcaa aagttctgcc tcatatgcta gtttgtttat atataaatct
     4261 ccacctgaag gcaatatccc tactttacac atagatttat catcagtaga tatatgcata
     4321 actatatctt cattatctac tatttcttct cccattttat aaattagctc ttcccttgta
     4381 cttggcctat gaaatccagt tgccactata atcttcacat caatttctgg attaacattc
     4441 ctaatccttc ttaatataat tggcatagtt attctacttg gtacaggtct tgtatggtca
     4501 cttgtaatta tgactacatt ctttttcccc ttaaccagtt cttccagaga attagagcct
     4561 ataggattat tcatagattc ttcaactatc tcttcttgag tcttatgttc tatataatta
     4621 tccgattttg actccaaaac accgagaaaa cgttcatcag gtatttctaa aatcattcct
     4681 tgttttgaat acggtacttt taactttacc atttttaatc tcccattata ataaactata
     4741 aaattggtat gtggtcatac cagttttaca tttatatgat agtaccatta tctaccattt
     4801 gcaagaataa tttattttat aacaaacttt taattttcat tttttctata atttttactt
     4861 ataaaatcca tatgttcctt tgctttctca catgcaagtt ctacatcatt ttctacaact
     4921 gcattgtata tagcttcatg ctgtttaagc aatatatttt cattaaaagg ttctgcgatt
     4981 attttttctc ttgcatcttc tataaatcca tcaaataatt ttgatgctgt cataaaaaga
     5041 ctttgaatta aataattttt actcaatgtt gctagtttac tgtgaaattt ttggtctaat
     5101 aacaccagta ctcgattatt atctttttta ttagtttcta ccctcatttc atctattata
     5161 tgtttcaatt ctataacttc agaagaagtt attctctttg aagcaagttt tgcaatctca
     5221 atttctagga ttattctaag ctctaatata tcttcaagtg taccattatt aagtttaaaa
     5281 atcatagata aaggttctat taaagttttt tctatatttg tacatataaa atttccttca
     5341 ccctgtctgc tttctatcac tcccatagtc tctaataccc taatagcttc ccttatggaa
     5401 gttctactca cattcatttg ttcagacagt tctctttctg atagtaattt atcccccttt
     5461 tttaactctc catttagtat tttatattgt atttgctcaa ttacttgttc ataaactttt
     5521 ttactagcta tactattaaa cattttttcc tccaatatga taatcgttgt tgtaatatat
     5581 atctattata tatcttaagc cattacattc atatattttt attactttta atataatatc
     5641 ttataactca aatttacagg tgatattatg aaaaaaaata aaattattgc tttttttgct
     5701 ccatctatca tagttggagt tctagtttta gggattatcc tatacccaaa tgaagctata
     5761 aaatctgcaa gagaaggctt ttctatatgg tctaatgttt tagttccatc actactacca
     5821 tttataattg gagcaaactt aattgttgat ttaaaaatag tggatattat agggtttatc
     5881 atcaatccca taactagatt tgtatttaat gtttcaggaa agagcgcttt agcttttgct
     5941 atatctacag tatctggtta tccagtagga gtaagtttag cttctgaatt taggagtaat
     6001 ggacaaattt ctaagtatga agcacaaaga cttgtgtctt tttgttctac atcaggacct
     6061 ttattcataa taggttcggt tggtacaggt atgttccaaa attcaaactt aggttattta
     6121 atgattctct gccattatct aggaactata ttggttggtc ttttctttag aaattatggt
     6181 aatgaaaacc ttccaaagac aaaattggat ttaaaaacaa atataaaaaa tgtaatcaac
     6241 attagaaatt caagtgggaa tggttttttt gttttatttg gaaatgctgt atttaatgga
     6301 gtaaatacat tacttacagt tggtggattt gtaattgttt tttcagtagt atttaaaata
     6361 ctatctcttt ttaatgtaat ctcattaata gcatcagtta tatatttgcc tctttcattt
     6421 ttaggtgtta gtaaagaact ctgtcaagca tttgtaagtg gtctatttga aattactata
     6481 ggatgcaata aagtatctag tataacaagt tctccagaaa ttttaagagc atctttagct
     6541 agttttttga taggatttag tggattatcc atcctagctc aatgttgtac atttctatca
     6601 aaaacggaca tagatttaaa attatacata ctaagtaaat ttgcgcatgg agttttagct
     6661 gctatcttta tatttatact ttatccaatt gcaaactctg ctgtgttggt ttctagcttt
     6721 gctgatacat acaacgttat atataataat ttaatctggt tttattatct tagctattat
     6781 gatacaattc ttcaaattgt agtaataatt tatctaatct cagccgtatt tattgcaaaa
     6841 aaacatatga aaactttatc tacaaatggg aaactaatgc gatataaaaa tacttttttc
     6901 actaagaaat tttcacgaaa aaaataaaac taaaaataaa actaataaaa cttaactaaa
     6961 tacttccatt tttttattat atttgtcata attttaataa cctttttaat tagtttaaca
     7021 gcatagttat ttcatcacaa tttaataatt ttattagaaa tatttttcaa aaaattctcc
     7081 ttaatcacat atatcacact tgtataagtt tactgggaaa tttttccatt atataatatt
     7141 tcatttatat tatataataa ataccgacct aaacttacca aatcaaacta agaggagtgg
     7201 ttgaaaatgg caacaagacc tatagaaata gacgaatata aaaagataat ggaactatta
     7261 catactggct ttacttatag tgaaaatggc gttgaaaaaa gatttagaaa aaatcctaaa
     7321 gttgcattgg cactaatgtt agaagctaat ttaggtctaa gaatatcaga tattttaaga
     7381 ttaaagatag gtaattttaa aggtaatatg ttggaaataa atgaaaaaaa gacgggcaaa
     7441 ttacagtata gaccagttaa taaaaatata attgagtcca taaatgaaca tgcaagaaag
     7501 tataatctta aatcaaatga ctacttagta aatataaaga caaaggctat tcaaaaacag
     7561 ttgaggataa tttgtaaaca cttaaatctg tataatataa gtacacatag ctttagaaag
     7621 ctctatgcta ctactcaatt tgaaaaaagt aacaataatt tagagttggt taaagaactt
     7681 ttaaatcaca gctctgtagc cactacacag cgatatataa gggtaactca gcaagctatt
     7741 aatgaagcta gtgaaaattt ctttattggt taattataac gtatacattt ttctattatc
     7801 ttattaattc accagatatt aaaaaagagt gtctcaaaat gaacttttta gttcatgaga
     7861 cactcttttt ttataaaatc aaatatattt ttattatttc aacactggaa aaaaggctta
     7921 tctctctatt ttgagacacc ctattaaatt ttcataattc ttgcataaac atattaatct
     7981 atcttcaata attttttaac tgattcactg taattatttc tttttacaat ttccaaaact
     8041 ctatcaatct catgttctga ctttgcactt acaaaaatcg ccaattcttc atcatctata
     8101 atatcataac tatctacata tttatctaaa cattctaaaa ttccatcttt attattatac
     8161 ccaccaaatc taactactgc actacactca tcttctataa gtccacttaa atccaatttc
     8221 ccttttgaaa aagactttat atttgaactt ctattatcta ttatatctat aatatctgca
     8281 taaacagcac ttcctgttgc acctcttcca gctcccttac ctacaaaaga aagttcacct
     8341 actgaatcac ctactaaaat aactacgttg aactcattat ctatctttga aagcatatta
     8401 ttattgtcca ctaatgctgg tctaacaaat ccacttactt ctcctgattc atacttactt
     8461 ctagcaacca attttatctt acaatttaat ttttttgcat attctatatc tttttcatct
     8521 attgaagtta ttccttctaa taataaatct ttccaatata ctatttttcc ataagataaa
     8581 gtagacaata tagataactt tctagcacta tcatatccta aaacatctgc atctggatta
     8641 acttctgcaa atcccaactc ttgtgcctgt tttaaagcga catcatacgg taaattttca
     8701 tcatacatct ttgataatat aaaattacaa gtcccattta aaatagcgtt tatgctcttt
     8761 atattgttgc cttccagtga ttctatcaat ggttttaaaa ctggaatacc acctgccaca
     8821 gatgcttcaa acttgatgct aacattattt aagttagcta attctataag gtcactacct
     8881 ttttcagcca gtaaatcttt attagctgtc actacatgta tttttttatt taacgctctt
     8941 gttacataat caaaagctgg atttaatcct ccaattactt caactagtat atcaatatcc
     9001 ttgtcaaata tatcttctat atcagtagtt atcttatcaa aatacttctt atacttgtgt
     9061 ttttctttat ttttaactaa aattccaaca acttctatat ctctttttga agtattattt
     9121 tctattaaat caattaatcc acttcctact gttccatacc ctaatattgc tatcttcact
     9181 gtaacatacc cccatcattt tgattatatt aaattattta tatatataaa tataccaata
     9241 aaaaaagctt gagtataaac tcaagccata tgacgggttt atactcatct ttcagcataa
     9301 atgctgcagg atttagcacc aatgtataat taaatatact ggttgccggg cttcacaggg
     9361 ccagtccctc tgccactctt gataagattg ctaatttaaa tttatgttta atagtataat
     9421 acaatttctt ccaattgtca ctattttttt aacttatttc cctaaaagga tataaactat
     9481 tatctaacag ctcttttagt tggtttaccc ttttttgtaa cattattatt tttagtcttt
     9541 gctttcgcct gttcatgtcc tggaaaaagt attttaggct cttcaatatt cctcttgtaa
     9601 atagtaaatt taaaaccaat agcctgcaca aattcagctc ttaaagcttc acatactgca
     9661 ttagcagttt ctttagtatc aagacctgca ttttctaata tagtaacttt tactaattct
     9721 ctagttctta acataccatc taattgctct aagaaactct ctgtaacacc ttctttacca
     9781 atttgtgtag taggctttaa agtatttgcc aaagatctta aatacgccct ttgttttcct
     9841 tttaacatat tctcacctct ataattctat acttaaatta tctataatct atatttaaat
     9901 taattgtaaa actcaaattc taattcataa attttaacca catctccatc ttctattccc
     9961 atttctctaa gcctatcaaa aacaccttga ctctccatag ctttttggaa atattgaagg
    10021 gattccatat catcaaaatt tacagaatac attattcttc taagtgcttt acctgtaact
    10081 acatacacac catcttcaat atctatactt aactcttctt cagtaccaat atcaagttct
    10141 ggtctataca tttcttcttc tgaaactagc tccacatctt ctacttcttt tagcatttta
    10201 gaaacatagg ctattacttc atctatgcct tgacgagttg ctgctgacat tttaaatact
    10261 gtatatcctc tgccttctaa ttcactctta aacttctcaa acttactctc atcttctaat
    10321 atatcaaatt tatttgcaac tacaacttgt ggtctctttg aaagcttttc attgtacaat
    10381 ttaagctcat catttatctt gtcaaaatct tcaatagggt ctcttccctc taatccagat
    10441 atatctacaa tatgtatcaa tacctttgtt ctctcaacat gtcttaagaa ctcatgacct
    10501 aatcctatgc cttcagaagc accctctata attccaggta tatctgcaag tacaaaacta
    10561 tctccaaact tagtttgaac aacacctaga tttggtgtaa gtgttgtaaa atgatagttt
    10621 gcaattttgg gtttagcttt agttacaact gatagaaatg ttgatttacc tacatttgga
    10681 aatcctaaaa gaccaacatc tgctatcatt ttaagttcaa gagttatcca tctttcttct
    10741 ccatctgtac cagattttgc aaaagctgga gcttgtctta ctgcatttgc aaagtgttgg
    10801 ttacctttac cacctatacc accttttgca actatagctg tatctccttc tttttttaaa
    10861 tctgctaata caagacctgt agcctcatct cttattactg tacctgctgg tacttttaat
    10921 actaaatttt ctccattttt accagctctt tttcctttgc ttccgtcgcc accattttga
    10981 gcttgatatt ttttctggta cttaaagtcc attagagttc taagccccaa atcaacttca
    11041 aatatgatgc ttgctccacg accaccatct ccaccgtctg gaccaccagc tggaacgtat
    11101 ttttctcttc taaatgctac cgaaccattt ccaccatttc cagccttaac aaatattctt
    11161 gccttatcta taaacaaatt cttcacctac ttaattaaaa acttttaatt agcattacca
    11221 aaaataccat tataaattca tcagtattat aagaaaaagg agtgcctcaa cactcctttt
    11281 atgtatatta ctcagctatt gctactggat atatactaac tttttttctc ttcttgtctt
    11341 ttctttcgaa tttaacagta ccatcaacta atgcaaataa agtatcatca ctaccttttc
    11401 caacattagt tcctggatgt attttagttc ctctttgtct aactattata cttccagcag
    11461 ttactaattg accatcgaat ctcttaacac ctaatctttt agatatagaa tctctaccat
    11521 ttttagaaga acctacccct tttttagatg ctaataattg taaattcatg tttaacatat
    11581 ggagtcaccc cctacttttt taaaattttt atattttttg ggtattcccg tttaatttct
    11641 ttaaccgcta attgaaagtg atttagtaat aattgtgcgt cttttacatg tgtatctttg
    11701 actatacact ctatatgacc ttcttctcct actacttttt caaattcaat cttttgtaat
    11761 ttgtctaaag aatttataac tgcaatagca ttagatgtaa ctgcagcaca tactatatca
    11821 tagcctattt cagcaaaatc agcatgtccc tttaaacaaa aaccttgcaa caagaaatca
    11881 tcattataat aatatttaac ttttatcata acttaaccaa taactaagcg tttatttttt
    11941 ctacaactat cttagtgtat gattgacgat gtccttgttt tcttctgtaa tctttttttg
    12001 ctttatactt gaaaactata actttcttag ctttaccttg ttcaacaact ttagcttgaa
    12061 cagatgctcc ttctactact ggagaaccta attttaattc tccatcttta gagcaagcta
    12121 atacttcgtt taaagtaaca acatcacctg cgttagcttc taatttttca acgaataata
    12181 catcaccttc agaaacttta tattgctttc caccagtctt tactatagcg tacattaaat
    12241 acacctcctc ggcctcaaac tcgccagtac aaggtacttc atttgaagat ttaaaccttt
    12301 actgtgcggc attacaatta ttaattataa aatatttaca ttttattgtc aactatttta
    12361 tcgaaaataa cattggtttt attgtgcttt aatgtactat ttgcgtttaa agaaatcttt
    12421 atattatatt tttcaccaat tttatcaatt atatccatat aatattcttt tatttgttca
    12481 aaaataaaat cattaaattc taccattatg tttttgtaaa cagtatgttc acttattctc
    12541 ataatttctt tttcaatact atctagtata taatgtacag attttattgt ttgttcacca
    12601 tcacaacatg gacaagacat taaataatac ttatcaatgg attctttttc tctacgccta
    12661 gcaacttcta ctaaaccaag ttttgtcata cctaatactt cagcttttct tttatcttta
    12721 ttaaattctt cttctaggat gtgtaaaatc tccttttgat gcttcttttt atgcatatca
    12781 ataaaatcga ttattattat cccagctatg tctctaattc taagctgtct tacaatttct
    12841 tttgcagctt caagattagt tttataaacg gtttcatcaa gtttaccagt tccaataaac
    12901 ttacccgtat ttacatctat aaccgtaaga gcttctgttt tttcaattat taaataacct
    12961 ccactcttta accatacttt tttatttaat aatttttcta ttttagattc tattctgtat
    13021 aaatcaaata catctctatt ttcctcaaga cacagtttat caacataagt cttatctata
    13081 cctcttaaaa tagacttaag ttcagagtac ttatcataac tattggtaat tatagattca
    13141 atatcatcat tcacattatc ttttacatat ttagttgcaa aatctaaaga cttatataat
    13201 aatttcggac ctataccaag tttatattct tttaaaatgt tttcatactt taatttcaac
    13261 tcttctatat ctttctttat ttcatcatga gtgcaacctt gagcctcagt ccttattatt
    13321 aatcctagat tttccttatt tactgcctta gtaatttttt ttaatctaaa tcgttctttt
    13381 tcatcagtaa ttttatttga tattgtagtt ctatcattgg aaggtatata gacaatatac
    13441 cttccagaaa tactaatctc agtgtttaat tttgcgcctt tagttcctat ttcttcttta
    13501 tttatctgaa ccaaaatatc ctgaccagat tttatagtac ttcccttttt taattgtaaa
    13561 taagcaagtt tcttaaatcc aatatctaca aaacaagctt ctattcctgg tataactttt
    13621 tttacgattc cacgatatat attggataca gtcttcttat ttaaattgtc ttcaacaaaa
    13681 agttctgtta atctttcatc ttcaagtact gctgttttct gggaccctat tagggactca
    13741 ataactatct ttttcacaac ttcacctctc gagcttacat aggagtcact aattccccat
    13801 cttctaatac atataaatct cttctcaata tatcaacatc taatgggtca atatcaagtt
    13861 caaacatctc taatatcttt ggtataagta tattagtatt taaattagtt tttgagcctg
    13921 tagctatagt agcagtaaga gtaatatgtt catcttctaa atttaaaaca tcaaaggttc
    13981 ttatcatagg tcttatatct acttcaacca tcttaccttt tttattcttt tttgttatga
    14041 ttatttcttt attattcata aagtcaatta cttttctttt tacaaactct ttcgtcatag
    14101 gtcttttcaa atctatatta aacaaatatt ctccatagtc tatcacagaa gaaagagaag
    14161 gtgtttgtct atcaatttct tttgctttga taaaatctat cccctctgga agttgaattg
    14221 atactttatt taaaaattcc tctactgata aatcatcttc ttctatttca atatctacat
    14281 actcaccttg actttctgtc cctaaagcca aagcattgcc ataactcatt ttagggtgag
    14341 gattaaatcc ttgagaatgt gataagttta tttcagctct tctaaacgct ctttgtaaca
    14401 atctctgaag gtcaagatgt gatatatata tcatgtcgcc ttccttttta aattttactc
    14461 ttattatctt actcatatta gcaaagcccc cttcctatat catgtatatt tattccacaa
    14521 ccattgcagt tatgtctaca atcagaagtg attttttctt ttttagcatt ttcgtcttct
    14581 ctaattaaga attttttact aatacctaca tctatatggt cccaaggaaa tacctcttca
    14641 tagtttctat ttctatgtgc ataaaaatct atagaaagat tattcttttc catagcttct
    14701 ttccatatat ctaaattaaa atgttctgcc catccatcaa atttagcacc tagtctaaat
    14761 gcatcatata taacttttcc tattcttcta tcgcctctag ctactactgc ttccatcaaa
    14821 ctagtctttg aatcatgata attgtatttt atattgttat ttcttaattt atttactaaa
    14881 tgtctctgct tattaataac ttcttctgta gtatcttgac catgccattg gaaaggtgta
    14941 aatggctttg gtacaaatgt agaagtactc actgtaacac taaaacttct ctttagcttt
    15001 cctccattta cttttctata aatatcaata actttataag ctaatttagc tataccatct
    15061 aaatcttcat aagtctcagt tggtaaacca atcataaaat acaacttaac actattccac
    15121 cccatctcaa aagctctttc tgttgcattt tccaaatctt cttctgtaac acctttattt
    15181 ataacatctc taagtctttg agttcctgct tctggagcaa aagtaagtcc agattttctt
    15241 acttgttgta ttttatcagc aatttccatt gaaaaattat ctaatctaag ggatggaagc
    15301 gaaatcccaa tattattaga tgcatattca tctaccaaat aatcagtcaa ctctgataac
    15361 ttactataat cactcgtact aagtgatgat aatgatattt catcatatcc agtattctta
    15421 actaatctac ctaatatttc tttaagtctt ttaacactct tttctcttat tggtctgtat
    15481 atcatacctg cttgacagaa tctacatcct ctagtacatc ctctaaataa ttctagtact
    15541 attctatcat gaacagtatc tatataaggt actattagtt tttctggata atctacagtc
    15601 tcaacatctt ttattatcct tttagtagga tttttagtaa tcccttctct attaggagtt
    15661 acactttgaa ctgtaccatc ttcattgtac ttgacatcat aaaaacttgg tatgtatact
    15721 ccttctatgc tagatatttt atataaaaaa tcttctctag tcgttttatt tttcttccat
    15781 tctttatact catttactac ttctaaatta acctcttcac cttcacctaa tattactaca
    15841 tctacaaaat ctgctaatgg ttcggaatta taagcacaag gaccaccaac cattataaat
    15901 gggtcttcca aagttctttc ttcttttaat attggtatat tggctaaatc taatatattt
    15961 aagatattag tgtatgaaag ttcatattga agtgtaaaag tgacaaaatc aaagtttgtt
    16021 ataggctctc ttgactctaa tgcaaataat ggtatacttt tttctctcat tatattttcc
    16081 atgtcaactg caggagaata cactctctca caaaatacat cttcatcctt attgattaca
    16141 tcatataata tatgactccc taagtgactc ataccaactt catataaatc tggaaagcaa
    16201 tgtgcatatc ttatcaattc actattacta gtatctttat gaattgaatt tatttcattt
    16261 ccaagatatc tagcaggctt ttctactttt tttaagattt ttttcaagtc tattttattc
    16321 atttattaaa attcctccaa acaagctctt tatttttatt cttatttata agtaatatta
    16381 tacacgataa aatattttct atcaaaaata taactaaaat attgaattta aaatacatat
    16441 tattcacaaa atagaatagc taaaaatatt taagaatatt ttccattaaa tttttattga
    16501 aatacaattt ttttacaaag tatgatatat tataaacata aaactattgt tttacatgac
    16561 ttatcatgac atcttttgtt tcattcacct caaaatgggg tatgttactt atataatgat
    16621 aaattttagg agggttaaaa atgagtaaag tttttgaagt aaaaaaagat atctacttta
    16681 ctggcgtagt agatgaaggt ttaaaagtat tcgacataat aatggaaact gagtttggga
    16741 caacttacaa ctcttattta atcaaggacg aaaaaacggt tttatttgac actgtaaagg
    16801 caaattttaa agatgagttt ttaagtaatt tatcagaggt tactgatata gctaaaattg
    16861 actatgttgt aattcatcac acagaaccag accatgcagg tagtttaaaa tacttattag
    16921 atataaatcc taatatagaa gtttattgta ctaaagctgc taaactatac ttagatggtc
    16981 aaataaatag accttttaac tgtcatgtaa taaaagatgg tgaaatttta aatatcggta
    17041 aaagaaatct tagatttata actgctccat tcttacattg ggttgataca atgtttactt
    17101 acattgagaa ggacaagact cttttaactt gtgatgcatt tggttgtcat tttgcaagtg
    17161 ttgatgcaga ggtagtgaat agtgaagatt atctaaaatc agctaaacac tactatgatt
    17221 gtatagttaa gccatttgct aaacatgttt taagtgctgt agataaggtg gtaggactaa
    17281 acatagaatt tgatactata ttgacttctc atggtccaat gcttactaaa gacccaatgg
    17341 ctgctgttaa aagatatgtt gagtggtcta cagaagctgt taatacaact aatcaaaatc
    17401 aagtttctat attctactta tcagcttata gtaatacttt agagatggct aaaaagataa
    17461 aagaaggact tgataaagaa ggtgcaaagg ctgaattata tgatttagaa gatatgacat
    17521 taacagaaat gcacgataca ttagtagtat caaaagtaat attactaggt tctccaacta
    17581 taaacaaaac tatggttaaa cctatgtggg atttattctc tgttatagac ccaatggcta
    17641 accaaggcaa gatagcagga gtatttggtt catttggttg gagtggtgaa ggtataacta
    17701 tggctgagac tttacttaaa tctatgtcat tcaaaatgcc tgtagaatct cttaagaaaa
    17761 aattcttccc tagtgaagag acattaaaag agtgtatggc atttggtgca gaatttgcaa
    17821 agttagttaa atagccatta gtcacacata atattattta aaataaatga ttttatattt
    17881 aaaaataaat taaaatggag ttgtctcaaa attaattttt ctaatctaat tttaagttca
    17941 actccttttt tattttccaa aatgactgat ataatgataa atgcaccctt tgtgcgaggg
    18001 tgcattattt ataatctgtt ctatttgtac actagtatat ttgtattaat tcacatatct
    18061 agcgtatgct accattcctc ttccagaatt agatgccgtt tcaccaattt ccactttaat
    18121 aattatatta ttttttttac agtattttga taattctgct gcagaacggt tcttcccagt
    18181 aaaatctaaa gaaaatggct tatcatattc aaaaggataa ctaacaggtt tactctctgg
    18241 tgctaatgca accataccat attgtgtttt cttaaatcct attacataaa ctgtatgctt
    18301 tgatgggtct aaatttgaat tactacttgt aaacttaatt gtatttattg atgagtcgat
    18361 tgaactacat ggaactccct catacatttt gttttgtggc ttcatattat ttccataaac
    18421 ttcattaagt attgcccctt cttggtctgc tatcatagtt tgattcccag gtccaactgg
    18481 cgcagaaggc ttagctggcg tagggttctt aacagttggc gttggattct gtgcctttac
    18541 tgcttcacca acagctggat atgctttctt gtcaaatggt aatgggtgag taagactctt
    18601 gtatatgatg tctgctcctg ctgatttgtt ggcatcaata tctacatgat acaaacgtcc
    18661 atcctcaaaa cgaataagat tccactgatg gtcatttgtt gtactatgta cataataaca
    18721 ttcaattccc atagcatcac ataaagcttt caagctccta cacattccag aacaagcacc
    18781 ttttttagta accaatgtat aagcagtatt ggctccctct gctgcgttcc agttaacata
    18841 tgttgtgttg tttttaatgt gattataagc aaccctaatc ttagcatctg tggtcatgtt
    18901 ctttgtaatt ttcttgttca taaagtctgc tgttgcttgt gctaccgaat taagttgagc
    18961 ttgtgataac tttggaccat atatactgtt ggttccagct acataacttt tcggtgtctt
    19021 tgcagtaaca tctttagctg tcataccata aactgttaca ctcatacatg aggttaaaac
    19081 catcgttgca atcaatagtt tagtagctaa tttcctgatt tttttcatat tagcattctc
    19141 ctttataata tattttactt tcaatttcct accattaatt aagttcattt tagatttaaa
    19201 atatggatta tcaacatgta tgcatagcaa ttcacgtggt catagaatat ttagatttct
    19261 tggaaaatct gttctatatt tcctatatag ttcgtataca atccaactca caaacctgca
    19321 tttttgatat catcacaata aaatgataat aattaatata ttcaaaaatg ttggtctgta
    19381 acaggtatgt caattttcca attattggta atggcgagag tgaggagaat tgtcaataat
    19441 acatttaaaa ttaaaattgt atacacttca tacattctcc cctaacaaca ttatacagat
    19501 tataatttgt atattcaata cattttttgg aaagtataat tatatcaaaa tatgtgatta
    19561 tgtatagata caatccacta tggagaaata taaaagaaaa gagtataaca aacaataaaa
    19621 aataagatga ttcaaatttt attttgaaac atcttattta ctctacaaat taagattatt
    19681 tggtgaatta tttaattatt attttttatt aaagaaattt taaatcttaa tataaaatac
    19741 gctattatac ataataatcc aaatgcaaat gctactggaa ttaacatctc cgattcaaaa
    19801 taaaagaaat attctaagaa aatatctgga tttactatat tcccattctt gtctaaaaaa
    19861 tcttttccat tatatcctaa atgctgtata aaattactta tgttattata atctgcttcc
    19921 ctctcatata ccatattagc attcaatcca gaagaactta aattagtgtt tccatctttc
    19981 atatctatta catatagtct aagagctttg actttactat acttatcttt atcaagtatt
    20041 ttttcaagtt ctaacttata ttcaccaatc tttgtcatat catgtctttc tgccaattgc
    20101 tttatttctc catcaagttc ttttcctaaa ttatacatat tatgttgtaa actattattg
    20161 taataccaca taaatccaga aattaaaaat gcaattatac ttatgtaacc taatactttt
    20221 ttaaacccca ttacaattga tttatgccta tccaatgata aagatagttc ttttattata
    20281 ttacataatt catactgcat ttcatcacca tcatcaaatc tttcaattgc ttttttacat
    20341 gcttcttctt catctaatcc ttctaattta aattcatttg cagattctat aagatggcat
    20401 ctcatttcct gttttaattc tatagtactt ttattgtcac attttttata tagtttatct
    20461 aaatattcat ctattagttt cataaattaa tccacctctc ccaaaaattg attcataacc
    20521 tttttaataa atctccattc ttgtttcttt atttctaaaa aatctttacc ttcattagtt
    20581 aaattataat attttcttct tccacctgaa ctttgttcat tgctataata agatttaatt
    20641 aaatttttag attccattct tttaagtgca agatacattg ttccttcttt taattcaaac
    20701 tcacttcttt ctcttacttg ctttgcaatt tcatatccat aacaatcttt cttttctaat
    20761 atagaaacaa ttaatatatc gatataacct tttaacactt ctttatttaa ctgcattatg
    20821 taccaccgcc ttttcaccta ctactctata atgtatagta cttatattta ctataataat
    20881 acatagtact ctataataca aggtttatat tctacaatag acttaaaaat aataaatagc
    20941 tgtatattaa tatttaatct ataaatacta atatacagct atttatcaaa ttttaaaaat
    21001 aaatttttgt tttattaatg ttgtcataac aacatttact tggttgaaat agtattacct
    21061 ataagtttaa atatatataa taatagactt gattctattt catattatta aaatagagta
    21121 atagtttaaa ttctactact ctatctataa tctatttcct aattatttaa tctcaaattt
    21181 agctcttcat catttaaatc tttcataaga tttctacagg tactagattt attccaacag
    21241 aaaaactagg gcattaaaca cttatatatc tgtttcttta gactgtaata ttaatatttt
    21301 ttaaatacgt tgacttttgc tttttctaac ttctctccat gatagttctc ctctatcaag
    21361 agcttttata aatatttctg ctgaagctag atttgtagct attggaacat gataaacatc
    21421 acaaagtctt attaacgctt gtatatctgt ttcatgagcc tgagatgtca atgggtctct
    21481 taaaaaaata actaaatcta tttcttgtgt tactattaaa gaacctattt gctggtctcc
    21541 acctaaagga ccagatgcta atctatttat atttaattca gtttcatcca ttattctttt
    21601 tcctgtagtt ccagttgcat atagtccata cttttttaaa attgattcat aacctataca
    21661 aaatccgacc atagtgtttt tcatttggtc atgtgctact aatgctatat tcatatatct
    21721 aatctcctca atttatgttt agatgtattt aaatttagaa atttattttc tttcttctca
    21781 tacacacatt tagtactaat cctaagtttg ctaaagatgt caataacgaa cttcctccat
    21841 aacttacaaa aggtaatgtt actccagtta ctggtattaa cgcaaccgtc atacctatat
    21901 tttggattat ctggtaacca aacattccca taacaccaac cactatgagg gttccataaa
    21961 aatcttttgc atctcttgca attgctaaaa gccttaatag gaatatcata aataagatta
    22021 tcaacactgc cattcctatt acaccaagtt cttcacctac aacagcaaat ataaaatcac
    22081 tatcttgtac aggtaaaaaa tcttcttgat tttgacttcc attgtaaagt cctttaccag
    22141 ttacgcctcc agaaccaatt gcaatcagag attgcataac ttgatagttt ccttttagag
    22201 ttacatcttc tggatttaga aaagcttcta ttcttacctt ttgatggtct gccatcatta
    22261 aatacatcag tggcattgac actaatagta tgattattcc tctttttatc aactttgaac
    22321 taagacctgc tgtgaacagc attgcaaata tcatacaaca aaatacaatt cctgttccca
    22381 agtctggttg tgcaatcaat aatccgataa atggaagaga ataaactaca acaggcataa
    22441 cttcctttaa cgtatttaat ttatcctttt tggattcaag tatctttgca taacttagta
    22501 caaatgttaa tttgactatt tcagatgtct gcaagtcaag tggtcctaag ttaatccacg
    22561 acctagctcc accttttact gtcccaattc caggtaataa aactatggct aacaaaataa
    22621 gacttattat ataaagcgct ttataatacc tgcctagaag gttatagtca aaaaataata
    22681 tgactataat cattcctata ccaagtacaa aagctaatcc ttgtttaatc aattgattat
    22741 atgaacctgt tgaattagca tgtgttgcac tactaagtat aacaagccca aaaataaaga
    22801 tagctaatac tgtaactata agtttccagt ctaactgttt tatcaactta attgtcgact
    22861 tataattaat attgattttt ttcaaagaat caccgtcttt ctatctttaa acatataatt
    22921 aaataaaagg ggcatatacc aataaggata tccccctttt aagcactaat tacatacatc
    22981 tatcttttat attctttagt ggtatattag caactaatgc agatacaggt ttgtcatcat
    23041 gctcacctct gcatttagac atttttattt caagaccatc atcttctatt tctgcataat
    23101 tagctattac tttcaaaatg tctgttttta tcatctctaa aagttgtggt gaacaatcta
    23161 ctctatcatg aactaaaact agctttaacc tctctttagc aacagattta ctagttttag
    23221 cctcgttaga aaaaactcta aataaatcta acacagatgt atcctccttt gctacttagc
    23281 catgctaaac atttttttaa gtctaccaaa gaatccatct tcaacttcaa gatcaagtag
    23341 aggaacttct tcatttagta tcctttttgc gatatttttg tatgcttgac cagcaagtga
    23401 cttagaatca agtatagctg gctctccttt atttgttgat ataattatgc tttcatcatc
    23461 aggaacaaga cctaacaaat ctattgctaa tatttctatt atatcttgtt tatccatcat
    23521 gtctccacgc ttaaccatat catttctaat tctatttata actaatctta tctcttttat
    23581 ttcatttgct tctaatagac ctattattct atcagcatct cttactgctg atatttctgg
    23641 attagtaact acaatagctc tatctgcccc agctactgca tttttaaagc cttgctcaat
    23701 acctgctgga caatctatta ttatatactc gaaagattct tttagtttct cacacaggtc
    23761 aatcatctgc tcaactgaga cagcattttt atctctagtt tgtgctgctg gtaataaata
    23821 tagattatca aatcttttgt cttttattag agcttgctta agcctacaag ttccttcaac
    23881 tacatctact atgtcataaa ctattcgatt ttcaagaccc attactacat ctaagtttct
    23941 aagtccaata tctgcatcca caactactgt ttttttattt tctaggctta gcgcagttcc
    24001 taagtttgct gcggtagtag tttttccaac cccaccttta ccagatgtta taactataac
    24061 ttcgctcata atactacccc ctatttttct ttctatttgt ctaactttga caaatagctt
    24121 tcgattacaa ttcttccatt acttacaaag gctatttctg ggctaatttc tgattcactt
    24181 tcataatttt cttcatcatc tggagcttct gcaatattat ctgctatttg taatatttta
    24241 ggattaagat ttccagcaac aacatatgca aattcattgc cttctgcacc tgcatgtaca
    24301 aaaccttcta ttttacccat tacaaaaaca ttacctcctg ctacaacctt agcaccagca
    24361 tttatatctc ccataacaac tgtatttgat tttgaaagga cttttgaacc aggtttcata
    24421 tcattcaata taactacatc accttcaaat tcaatatttt caccagatct tagggtattg
    24481 acatattttg ttggaaaatt actattttct tcaatttttt gatcttcaac aaattccaca
    24541 tcaaatctag aagtaattcc ttctttaagt tctagaatct ccatgtcagt taaacaatca
    24601 ctattaattt tactaatttt agccccatta aaaaagccaa catatgcttc caatttgttt
    24661 attatttttt cctgtatttc ctcaaatgga gcttctcttt ttatatttac tattatccct
    24721 cttttattac ccttgaactc tactagttct tgactacaaa tttctcttaa agacataaca
    24781 acctccagag tgatatatca tttatattct tcaaatacgc tttaaaccct tttatttttt
    24841 ctatataaag ctaaagttta tacatagatt gagctatcta ttaatttgtg actcgaaatt
    24901 tatattttcg tcagaagaat tgttaacatc attcgtcttg ttgtcatttt tactattagt
    24961 tggctctaat cccatataag ttccaataac ttctctagtt ggtaaaagtg agaatacact
    25021 tgaatcacct tgaggaatta cacatacaac agctatttct gggtcatctg ctggagcaaa
    25081 agcaacagtc cacgtaaaag aaccataatc ttgtttaaat ctatctattt ggtcatctgt
    25141 tatttttgga tttaattctt ttatagcttt tcttagatat gaagaattca ccttatcagt
    25201 gtcctctaat ctaactttta ctccatcttc taattcttcc tctaatttct ttctttcttc
    25261 gtctttcaaa tctttatttt ctaatttctt ttttatttcc ttttccttag ctaatgaaag
    25321 ctctttttct ttttctgctt tcatcttatc agctagttta atcgcatcat ttaggttgac
    25381 attataagat gacatatgac tttttaaata ttcatactcg ttatctgtag gtattttccc
    25441 acttttctca gctgtaccag tttttgctgc tacatctatt ggaaaatcag caaaagcact
    25501 cttcgctgta ccttgtcttg caaccaattt catacctttt gttaattctt ttaagttatc
    25561 tggattttta aaaggtattt tttcgacttt cttctggtca ttaattttaa ctgatgaata
    25621 atcacttgaa acagctctat caactacaga taattctact aaattacctc catttgctat
    25681 agcagctaca tatcttgata tttgagctgg tgtataagca ttttcacctt gacctatagc
    25741 taagttaaat gtatctgcag tactccattt tgcaaagtta aaataactaa atactgctaa
    25801 atctgctact tcttcaattc tatcttcttt aacatccaat ttttttagcc tattcattgt
    25861 ttcaactcta ccaggagttt tcttttctgc tgcccagctt acaatctcat tgattctttt
    25921 ctcatattct ttaggatttt tttctctagt tatatcaaca aaatcatttg ccatttctct
    25981 ttctaaattt gactttagaa gagcttgtgt tgatttcaat ttatcttctg tgctaggaac
    26041 tttacctgct ctttcttcta cttcatcttg aagccctgta ttttggtcaa gcccaaataa
    26101 ttttgcatac tcaagtattt tatttgcatt catatctata ccaatgcttt ttccatctgg
    26161 ccatgtttta cctgtaccaa ttgttgccat atatatatta caagactctt gtattgcttt
    26221 atataagttt gtcataccat ggtttcctct accatggttc catacatagt caccaaaaga
    26281 ttttttacct aacattataa ccccagggtc atttatagta aagtttggat ccagaccatt
    26341 ttctaacgct gccattgaag ttaccatctt aaatgaagaa cctggctgaa attccccttg
    26401 tgtaaccaag tttaaaagtg gacttcctgc tagtaagtca tttggatttt ttggttgaag
    26461 tgctttataa tcctctgtag aaataccttt tgcaaattta tttgggtcat aattaggata
    26521 acttgatgaa gctaatactt ctccattttt aacatcaata gctataagag ctgctgactg
    26581 tgcttttcct gcatatgcac taattggttt gtccccaaat ttacttttaa aagtacctcc
    26641 tttagaagca acttcgatta tctgttttaa tgcattgtct gaaacttctt gtaaatcttt
    26701 atctagtgta agatacacag tatctcctga tttaggtttt ttagattcaa tttctttact
    26761 gattctaccc aatgcatcaa ctttaaccat tttataacca tcagttcctc ttaatctact
    26821 ttcattactc ttttctactc ctgcaagacc taccatatct ccagtttcat aacctttttg
    26881 aaggtatgat tctatttgag tggatggcat ttttcctaca tatcctaaca tatgagaagc
    26941 taatgaccca ttaggataat atcttactgg ttctactgct attgaaacac caacaaggtc
    27001 catagcactt tcttcaattt gagcaatcgt agtttctcct acatccttag caatagttac
    27061 tggattatat tgagaatatc cttttgattt tatcaaatcc cttacgacca ttatttttct
    27121 tgcatcttca tcactcaaac ttttatcaat ttctaatgca tcactatttc ttactttttc
    27181 aaacgcttct ttggcactca gtttagtttc ttttatctta taactagcca accaatctct
    27241 cttatctctt tctgctgtga acatccattt actaactaaa ataggtggat aatatccatt
    27301 ttcatttagt tttgcctgta atcttgtcgc atccaatctt ttatcttctt gagataatat
    27361 tccagctgat ataagtttgt ccaccaagta ataaaaactt tccttagcat tataatcatt
    27421 tggaatacca ttttctgatt tatattccct aatatctctg tcatatgtat aatagtactt
    27481 tccattttct acatatatag gaaactcatc tacatattct tcaccatttc tctccagcaa
    27541 atttataagt tttaatgata tttcatttgc tcttgaatgc ttatttgcat ctttcttatt
    27601 aatatcgtta cctgaaactt gaacagtaaa taagttttta tttcctgcca acagtcttcc
    27661 atatctatct tttatttctc ctcttggagc ttctattgcc aactttttat atgttttatt
    27721 ctcagctaac tcattgtaat attcatattt aaatgtagtc atatagatta tttttactaa
    27781 aatagctaaa aatatcacgc ccatgactat cttaattatt tttagtctat caacttgttt
    27841 attttcttcc atgaaatcac caactaatct tctttaagtt ttaaaactgc tcttttagat
    27901 aagcgatata ttactaaacc aattaaacta ttcactattg gtgctactag tagacctttt
    27961 acaaaaagtg ttgatatgtt gtagctttga taaattatac tagatgtacc tatattgaca
    28021 attgaatcaa ttaaactgcc tataaaaatt aaaacgaaag taataatata actaccttta
    28081 tatagctgat ctctcatgta tccaattgca tatgcaataa taaacaaaat taatgcattt
    28141 acaccaaaaa ttccaccaac ggttatgtct ttaataagcc ctattattac tgctataatc
    28201 ccaccttcta attcatctaa ataaagagag attatggtta catatataag aactaaatta
    28261 aagcttatgc caaaaatatc tatataattt gttatactat tttctatagt cataagcaca
    28321 atccccaaca gacaaagtaa aacttttttc attgttttta tcccctttat cctatatttc
    28381 ttggttctat gactacaacg tcatttatat tcttaaaatc aacataaggt tttacaacta
    28441 catattttaa tgacttatct ttatcatcaa ccactttttc aacttcgcca attggtatac
    28501 catctgggaa gaatccaaga cctgatgttg ttattatatc tccttgaatt acattatatg
    28561 atgagtcaaa catatatcct tgcaaatatc ctttactatt ataactatct ttattatcta
    28621 aagtagtatt ttgagtaatt gtacctttag cattggcatc ctttgctagt ttaaagctta
    28681 cagatgcctt agaatccaat agtgaaattg ccttactata attgttggaa acctcataaa
    28741 ctatgccaac taatccacta ccattcataa ctatactttc tttttttaca cctgaatttt
    28801 ttcctgcacc tatgacaaaa ctctcatacc agtttccatc atttttacca acaacacttg
    28861 ctgaaatact tgtcgcctta tactcttctt gtacaaagtt cagtgtcttt tttaactctt
    28921 ctagcgattc tgttttatct agtttggcat ttaaagctat catatttttt ttaagttttt
    28981 cattttcttc ttctaatttt tttacctttt tagaattatc tttaaaattt gctacatctt
    29041 taaaaccatt tttgataaaa gaaaatccat catttattcc cttacctaca cttgtaatag
    29101 catctgaagc tactcctaaa tttactggac taccactaga aaatttacca attgatatac
    29161 ccacaattcc aattaaagtg atagcaacta cgcccgttgc tatcacttta acattaatcc
    29221 tttttttctc atttttgttc ttgtcaaatc tcaaggccat caccaacttc taattcttag
    29281 tattcatcat taatactttt tcaaagattt cttggtcttc aacagattta cctgttccaa
    29341 gtgcaacaca atcaagaggt gtttctgcta tttgtacaga cataccagtt tcctgtgtaa
    29401 taagcttatc aagacctcta agcaaagcgc ctcctcctgt tagcattatt ccgttttcca
    29461 ttatatctga ggctaattct ggtggagttc tttctagtgt agattttatt gcatctacta
    29521 ttgaacttac aggttctttt aatgcttctc taacttctgt agagcatatt tctattgttt
    29581 taggtaatcc tgagattaaa tctctacctc ttatttgcat atttatttct tcatcatctt
    29641 taaatgtaga acctatgtta atttttacat tttcagcagt tctttcacct atcataagat
    29701 tatattcttt ttttacataa gccactatag actcgtcaaa ttcgtctcca cctattctta
    29761 tagatttagc agtaacgatt cctcctaaag atattacagc tatttctgaa gtacctccac
    29821 caatatcaac taccatatta ccttctggtt cttcaacttt taatccagcc cctatagccg
    29881 ctgccattgg ctcttctata aggaatgcat ctttagctcc tgcttgtctt gcagcctctt
    29941 ctatagctct cttttctact tctgtaactc caaaaggaac acatatagct attcttggac
    30001 ttacaacacc ttttttatca gccgcttttt gtataaaata gctaatcatt gattgagtta
    30061 tgtcaaaatc agctattact ccatctttca taggtcttat agctactata tttcctggtg
    30121 ttctacctat catttttttg gcttcttcac ctactgctaa tacctcttta ctatcatctc
    30181 ttattgcgac aactgatggt tctctaacaa caataccttg tccttttatg taaactaatg
    30241 tatttgcagt ccctaaatct attcccatat cctttgtcat cttattaaaa ctaaaaaaac
    30301 cttttttttc tttctttttt tccttagcca tgattttact ccttcctact attaagaatc
    30361 atgtttaaaa cattctccta ttattttatc acatataaag tcaaattatc atattttctt
    30421 taaagctaaa gtataatcca tctccaataa ttatatggtc tattatttct attccaatta
    30481 tttctccaca tttaataagt cttgatgtga tatttttatc ttctcttgat ggttctacac
    30541 ttcctgaagg gtgattatgc atcactatta tcttacttgc acttcttctt atagcttctt
    30601 taaaaacctc tcttggatgg actaatgacg agcttaaagt ccctatagat acatctacat
    30661 cagatattat ctcatttttt gtgtttaaaa gaaccgcttt aaaaacctct ttttttaaat
    30721 accttaggct atccatataa tacctctgta tatcccaagg attccttatt ttatacttta
    30781 taggtttaaa actagctact ctagagccta gttctaaagc tgctttaatt tgggttgatt
    30841 ttgataaccc aattccatct atattacaca gctcctctat tgtcatatct tctaaatgtc
    30901 taataccctg aatatctcta tttattatat agttggctaa ttcaatagca tttttattct
    30961 tgttgccagt tcttaaaagt atagccaaca actcagcatt tgataagctt tttacgcctt
    31021 tggcaagcat cttttctctg ggtctttcct ctggtgccat ttcttttacc ttaatggttg
    31081 aattaaatga ctttttcaga taaatcacac tccataaaaa agatttatac taaaatattt
    31141 ttttaatagg tcgcctaacc ttgaaattgg aagaccaact atattaaaat aatctcctct
    31201 aatttcttca actaacaaag ctccataacc ctgtatacca taggctcctg ctttgtcaaa
    31261 tgactcatta gttttcagat aatcctcaat atcctgctct gataacgttt taaatttcac
    31321 attgctgatt acatagtcaa ttaccttttt atcttcgcac aagtttatta agctaatacc
    31381 tgttatgact tgatgctctc ttccagatag tctttttaac atatctcttg cacaagactc
    31441 atcttttggt tttcctaaaa tagcattgtc taaaacaaca actgtatcag ctccaataac
    31501 aacatcttca ttatgttcag atgctacaga catacttttt tcaaaagcta atctcataac
    31561 taaatgtttt ggtgtttcac cttccaatat aatctcatca atttcatttt taattatatc
    31621 aaatcttaca ttcgtattct ctagaatttc tttccttctt ggagaggctg atgccaagat
    31681 tatattcatt tattcacctc atttgtacgt aatttgtacc tatttagtct atcactatat
    31741 tgtaaaaaat tcaacagaaa tgtcgaacct tttttgttac actattgtta tatttattac
    31801 cattagaata aatatacata aaatagaggt atggaaatta ttccatacct ctgttttatg
    31861 tactcattag agatatggaa attattccat atccttattt tgtccatatt acaaaatttt
    31921 aatagctttc tttggacatt tttccataca taaatggcat cctacacatt tatctgcatc
    31981 taccttatgt ttttctttta attctccctc tattgcatca aacttacatt gttttttgca
    32041 cactgtacat ccaacacaaa gttcttggtc aatagtaact ttctttttct tagttatgtc
    32101 acctgatatt acttttgtag ggcattttgc tacacattgc atacacccta cacacttatt
    32161 agggtctatc ttagctattt tgtcttcaaa tattattgca tcaaatttac aagcttttac
    32221 acacattcca cagccaatac atccagcagt acatttttcc ttaacagctt taccaaactc
    32281 tttgctatta cactctacaa ctacttcttg actttctggt tttgtgatta ttataccctt
    32341 aggacaaact tctttacatt ttccacaatt tacacacttt tcttcatcta ttactgctat
    32401 tccatcaact atagaaatag catcaaattt acaagcatct ttacatgttc caagacctaa
    32461 acatccaaat ttacacatct tagcacctga gtttaaaaca tttgctgctc tacaatctga
    32521 tattccttca tactcatatt tatcttttgc acttgaacaa gttcctttac aaataacttt
    32581 tgctacttgt ttctcacctg cttcagcact tattcccatt atttctccaa cttttgcacc
    32641 aacatctgct ccacctacag ggcaaccatt aactggtgca ttgccttcaa ctatcgcatt
    32701 tgcaagacct ccacaacctg gaaatccaca acctccacag ttggctcctg gaagtactcc
    32761 tagtatagct tccactctct cgtctacttc tacagcaaac tttttagatg caaaatctag
    32821 tactatcccg aagattaagc ccataattcc taaaactaat acagctgtaa gtatcaccat
    32881 tttcacccct cttttttata gctttataag tcctgtaaat cctaagaaag ctattgacat
    32941 taaacctgct gatataagcg ttatagggaa acctttaaat gcttctggta tatcagctaa
    33001 ttctagtctt tctcttatac ctgcgaatat tactattgct aaggtaaatc cagctccggc
    33061 tccaaatccg tttattattg tttctactaa attataactt ttttgaacat taactagagc
    33121 tataccaaga actgcacagt ttgtagttat aagaggtaaa taaactccta atgcttgata
    33181 taaagatgga ctcatctttt gaattaccat ttcaacgaac tgaactatag aagctataac
    33241 caatataaaa gctattgttt gtaagaatcc agttccagtt tttactaata aaatctgtat
    33301 aaaataagtt ataattgaag ctagagttaa aacgaacgta actgcaactc ccatccctac
    33361 tgctgtatca accttcttag aaactcccaa gaaaggacat atacccaaga attgagatgt
    33421 tataacgtta ttaacaagaa cgatacttaa aaataaaagt attaaattca tttattacac
    33481 ctccactatg cttttttact tcttaattta ttaaatcctg caaataagaa tcctaatgtt
    33541 aagaatgcac ctggtggtaa tataaatatt aatactggtt ggaaagatgc tccaaataat
    33601 gtcattccaa ataaactacc atttccaagt aattctctta ctgcacctat tattgtaagt
    33661 gcaacagtaa atccaagacc ttgacctaca ccatcaacta ttgaaggcat agctcctgtt
    33721 ttgaaagcaa aactttctgc acgagctaat attaaacagt taacaactat taatggtata
    33781 tatataccaa gagccttatc aagagcagga acatatgctt ttaaaagcat acctactatt
    33841 gtaacaaatg tagctataac tactataaat ataggtattc ttatcttatc tggtgtaatt
    33901 tttcttatta aagatataac taaatttgca catattaaaa ctgctgctgt tgaaagaccc
    33961 ataccaattc catttattgc tgaagttgta acggctagtg ttggacacat acctataact
    34021 tgaacaaatg ttgggttctc atctattagc ccatttttaa atactttagc taaattcata
    34081 attaaccctc cttatttatt aagagcacta ttgaaaacat ctatagcagc atttactcct
    34141 gtagtaactg ctgtagatgt aatagttgca cctgatattg ctaatatttg attatctgct
    34201 gttgtacttc cttttgctac ttcaagaggc tcagcagttt ttcctttgta ttgaccctta
    34261 aatgcatcat ccttagcttt tgctccaaga cctgctgttt ctgacatatt accaatgtca
    34321 acacctgtaa cttgaccttc agatgatata cctaccataa cttcaatttc tccaccatat
    34381 ccacttggtt tagcttttaa agtatatcca accacttcag aaccatctaa accttcatac
    34441 acttcagcta taagaccatc tccaaggcct ttgtaagtat cttccttcat ttctttaaat
    34501 tcttttgctt ctggaaggac tgcttttcta agttcattat ttgcttgtat atttctttgt
    34561 tctattactg gagctgtaac ctgattagta gctccaagag ctaatgcagc tattgcactt
    34621 atagcaagta aagtaccacc taatctcacc atactgttca ttatttagcc acctccccaa
    34681 atactctatt tctaacaaac ttatctataa gtggagcaag acagttcact aatagtattg
    34741 agtaagatac accttctgga tatccaccat acattcttat aacagttgtt ataagaccag
    34801 ctaatacagc gtatattatt tgaccttttt tagtcatagg cgaagttgta taatccgtaa
    34861 gcatgaagaa tccacctaac ataagtcctc cagcaaacag ttgatatatt gcgaaagtta
    34921 tattaaatcc acctaaaagg aatgttaata taaatacagt tgctatgtaa aatactggta
    34981 taacataatt tattatgcct ttatacatta ggtatactcc acctaataat aataatattg
    35041 ctgatgtctc acctatacat ccaccaatat tccctatcat catgtcagca agactaattc
    35101 cattgctaga aagatctgcc agtcctgctg ctccattttt caaaaagctt aatggagttg
    35161 ctgtagtaac tgcatctaaa tttttaccta tccagttaac acctggttga gtccaagcag
    35221 tcattgctac tgggaatgat gctaataaaa atgctcttgc agcaagtgct ggattgacaa
    35281 agttacatcc aattccacca aataccattt taactactaa tattgcaaat attcctccta
    35341 ctagacacat ccaccaagga agtgatgctg gtacgttaaa tgctaataat aatcctgtta
    35401 caacagctga aaaatctcct atagtacttt tttgcttcgt aaatttttga tataaaaatt
    35461 cagtacctac tgtaccaagt atacaaaaaa acatagcact caaagcatta agtctaaaga
    35521 agtatactcc tgctactgct gctggaagga gtgctataat aacttgtttc attatatatg
    35581 aagtatcttc attacttctc acatgaggag aagatgatac tatcaactta ttttccatcg
    35641 tttttccccc ttaactttct ttatttctga gcagcttgct ttcttctctt tgctcctatt
    35701 tctctctttg ctgatcttat agattgaagt aatggtcttc ttgctggaca aataaatgag
    35761 caagacccac attctataca atccattgct ctatgatatt cagctgtgtc atagtcatct
    35821 tttaaagaat atgcacttat gaaaagtggt tgtaagaatg atggacatac atctgtacat
    35881 cttccacatc ttaaacagtt ttgaatatct ggagtacgtg attcttcctc atccaaacat
    35941 aaaattcctg aagaaccttt gttagtcgct atttcagtag tatattgagc tattcccatc
    36001 ataggtccac ccattataac cttaccaatc ttcttatctt ctttaaatcc accacattgt
    36061 tctattattt ctgaaactaa tgttccaact tttgttatta ggttctttgg ctctttgatg
    36121 caactacctg ttattgtagt gattctttca accaaaggca tacctgtttt aatagactta
    36181 gctatctgtg ctgctgtggc aacgttgtca acaactgcac ctgctgctat tggtaatcca
    36241 ccagatggaa cttctttgcc tgtacacgca taaataagtt gtttctctgc tccttgtgga
    36301 tatttcactt gaaggccaac aacttcgatt tcgctatagt ctttagctac attttgaatt
    36361 gcttctatag catctggttt attcgtttca attcctataa atcctttttt gacatctaat
    36421 accttcatta atgctcttaa accaaacaca acatcttctg gattttcaac cattaatctg
    36481 tggtctgcag ttaagtatgg ttcacattct gcaccattta atataactac ttctgccttg
    36541 ctatctggtg gaggagatac ttttacatgg ttagggaatg tagctccacc catacctact
    36601 attcctgcct cttttatgat acctactata tcttctttgc tcaaatcctc taactgacct
    36661 tttggttgaa cactctcatg taattcttcc ttaaagtcat tttcgataac tacacattga
    36721 gctgaacctc ctggtacttc atgttgttca atagcaataa ctttacctga tactgaagaa
    36781 tgaacgttac atgaaacaaa accttgttgt tcacctattt tttgcccaaa ctttacttca
    36841 tcaccaactt caacaatagg tttagctggt gcccctatat gttgctgaag aggaatgtaa
    36901 actatctttg gagcttgagc tttttcaagt gcctttgtgt tagagtactc ttttctatat
    36961 ggaggatgta tccctccctt aaaagttaag agtttcattg ttttaccccc ttatctataa
    37021 aaaaacattt tttctgcctt ctataagtat actatatata ttaaaaaatc ttaacaattg
    37081 ttaaaaaaat atccgtattt ttataattta ttttataaat caatacctct atattaagtc
    37141 aaaccgagga aaaggattgc ttaattaaac aatccttttc atatagcttt ctaaagtcca
    37201 aattttctgt attttatttt atagaattta taaacataga gtactcctgc atggatgata
    37261 aaagcagact tttacttaca ctatattttt cttcatttgc tgcttttgaa gctgtatcaa
    37321 ttttttcatt cacattcttt acatactcta ttaaattatc tttaaataaa cgcatttcag
    37381 aatagtcaat cttttcggct tcttttgata tattttgtga tattgccttt ctatttgtca
    37441 aaatagtatt atatttttcc atatctacat tattttcagc attcgaccaa aaacttgatt
    37501 cttctttaaa gtttgttatt aatttattta attctttaga tatactctct atataagcgt
    37561 agttactggt atactctaaa gacaacatag gtgcatctaa gtgtgataaa aatgcatctg
    37621 gaaacacctt tcttacactg cttatctgct ttctaacatc attttcatca aaagaggaat
    37681 aggtctgtat tttttttact ccatccttct ccataactga aaaaggtatg tcattattaa
    37741 ctaatgatgt ctgtattttt ttcaaatcat cattattatc tattgcagca acttgaatag
    37801 tgtacatatc ccagccttct atagtagcta acttgacttc ttctggctct ttagtgttat
    37861 ttaccgcttt ttctggatta gtttcttgtt tatcatctga attggtttgt gatttagatt
    37921 ttttcccttt ttttattgaa tttaattcat cagatatatc tttataagtt atatctgatg
    37981 aattatttag aaatggtatt ttagccgata catactccaa tatcttacta tcttttattt
    38041 ttgtataaga ataatagcca attagacaca agcaagcaat cgttataaca tatttacgta
    38101 aatcaatctt atgtctatta ttattaaatc ctctgtatat cgtttttctt ctattcatta
    38161 gtttgtccct cccaaaatta tattattaat aaagtatatt tttaagagtc acaatttatg
    38221 aatataaata attatttctt ctaatttttt aataagaaat tgtacttact aaacaaatct
    38281 tcttgcacca agtaatactt tagaccaata tgaactagtt aaattatcca ctttaacctt
    38341 attaggatta gtctgagtac cactacaatg gataaattta ctatttccta catatatacc
    38401 tacatgatta gttgttccat caccatcagt gtcaaaataa actaaatctc ctggtgcata
    38461 atttcccata gaaattgcac ttccaaaatt agcctgttct ctagaaactc taggaataga
    38521 aacgcctaca gaatgtttaa aaacatactg tgtaaatcca gaacagtcaa atttatcagg
    38581 tcctgaagct ccccattgat atggtattcc aataagagta tatgcaaaat ctacgattgt
    38641 tgaacctttt gctgtagatt tatctgaatt tccagtaaat gatggctttg agttactatt
    38701 agattgagaa ttttggttag atgatgaatt tggtttttct tttgtatcct cattagtctc
    38761 agaaatataa ctggcactca cccatccaat tgttccactc gataacttta ccttatacca
    38821 accattactt ttagctttta attcaacaac atctccacca tttaattttc ctattataga
    38881 atagcttgtc ccaggaccac ttcttacatt taaactcaca gcagatgtta ccttaccatt
    38941 cttgccttca attgattctt cgctagatgg ttttttatca gaattattag tactatttga
    39001 attactagaa ttattcgttc caacatcctc tgatgtttta gagatatatt ggctactagc
    39061 ccatccagta actccatttg atagttttat tttataccat ccattgcttt gttctagtaa
    39121 ctttactaca tctccattat ttgctttacc aactaatgaa tagttagtac ctgcaccact
    39181 tcttacattc agtctagaac tcacatttac tttaccattt ccactaatag ttgtcccact
    39241 tgaagttgaa ttattttgac ttgatgtacc ttcagacgaa ccacttgttg atatgtattt
    39301 tgcacttccc catccaacaa cagaactcga tacccttact ttataccatc cattagactt
    39361 ttctaaaatc tctacagttt ttcccttgta taattttgct accttatcgc aatcagaact
    39421 tggtccactt cttatattca aggcacttgc tgttacagtt cccttttcaa gagcacttgc
    39481 atttatggag ctaacagata ctgctactgc cccaattcct aaagctgcta tagctttttt
    39541 cactactatc actcccccca acaaattttt atagtcataa attcataaca ttattatcca
    39601 tttttagtcc ctacaattta atgataactt attttcttat taattgtaaa gaaattataa
    39661 acatatcctt aaaattagtg atttttagga agtatttcaa tccaataatt atctgggtcc
    39721 gctataaaat aaattcccat actttcattt tcaaaacata tgcaatctaa atctttatga
    39781 agtttttttg cctcatcaaa ctcctcaact tctaaagcca gatgaaattc attgtctcct
    39841 aaattatatg gtctatccca atctctaagc caagttaatt ctaatgtatg actagtaatg
    39901 ccatctccta aataaactaa tataaaactt ccatcttctg cttccttgcg ctttacctct
    39961 ttaagcccta aagctttttt ataaaaatct aaactttttt ctaagttagt aacattgaaa
    40021 ttgttatgac aaaaattaaa cttcattttg aaatcactct ccaattttt
//
LOCUS       DAEPXW010000031        39749 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.032, whole genome shotgun sequence.
ACCESSION   DAEPXW010000031 DAEPXW010000000
VERSION     DAEPXW010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39749
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.032"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(26..2050)
                     /locus_tag="KRM55_001559"
     CDS             complement(26..2050)
                     /locus_tag="KRM55_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1593808.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            2440..3108
                     /locus_tag="KRM55_001560"
     CDS             2440..3108
                     /locus_tag="KRM55_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593809.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            3110..3595
                     /locus_tag="KRM55_001561"
     CDS             3110..3595
                     /locus_tag="KRM55_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH1593810.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            3656..4777
                     /locus_tag="KRM55_001562"
     CDS             3656..4777
                     /locus_tag="KRM55_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBH1593811.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTVVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            5058..6248
                     /locus_tag="KRM55_001563"
     CDS             5058..6248
                     /locus_tag="KRM55_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1593812.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEISRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    6382..6637
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6696..7697
                     /locus_tag="KRM55_001564"
     CDS             6696..7697
                     /locus_tag="KRM55_001564"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBH1593813.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            7801..8190
                     /locus_tag="KRM55_001565"
     CDS             7801..8190
                     /locus_tag="KRM55_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBH1593814.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            8351..9559
                     /locus_tag="KRM55_001566"
     CDS             8351..9559
                     /locus_tag="KRM55_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBH1593815.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(9645..10721)
                     /locus_tag="KRM55_001567"
     CDS             complement(9645..10721)
                     /locus_tag="KRM55_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1593816.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVKEILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRICILKPNENKLLISSLKAIFK"
     gene            10950..11477
                     /gene="hpt"
                     /locus_tag="KRM55_001568"
     CDS             10950..11477
                     /gene="hpt"
                     /locus_tag="KRM55_001568"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH1593817.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            11566..12498
                     /locus_tag="KRM55_001569"
     CDS             11566..12498
                     /locus_tag="KRM55_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBH1593818.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFSVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            12560..13786
                     /locus_tag="KRM55_001570"
     CDS             12560..13786
                     /locus_tag="KRM55_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1593819.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            13870..14091
                     /locus_tag="KRM55_001571"
     CDS             13870..14091
                     /locus_tag="KRM55_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH1593820.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            14280..14450
                     /locus_tag="KRM55_001572"
     CDS             14280..14450
                     /locus_tag="KRM55_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593821.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(14543..15004)
                     /locus_tag="KRM55_001573"
     CDS             complement(14543..15004)
                     /locus_tag="KRM55_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593822.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            15187..15654
                     /locus_tag="KRM55_001574"
     CDS             15187..15654
                     /locus_tag="KRM55_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593823.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            15697..17460
                     /locus_tag="KRM55_001575"
     CDS             15697..17460
                     /locus_tag="KRM55_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBH1593824.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            17468..18076
                     /locus_tag="KRM55_001576"
     CDS             17468..18076
                     /locus_tag="KRM55_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1593825.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            18148..18717
                     /locus_tag="KRM55_001577"
     CDS             18148..18717
                     /locus_tag="KRM55_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH1593826.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            19235..22774
                     /gene="nifJ"
                     /locus_tag="KRM55_001578"
     CDS             19235..22774
                     /gene="nifJ"
                     /locus_tag="KRM55_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBH1593827.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(23166..24062)
                     /locus_tag="KRM55_001579"
     CDS             complement(23166..24062)
                     /locus_tag="KRM55_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBH1593828.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PGNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPEDNNNSDSTNKPD
                     DNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKKSQDMIDNNYF
                     SHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGHRKNIMNPNFS
                     KIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(24558..25892)
                     /locus_tag="KRM55_001580"
     CDS             complement(24558..25892)
                     /locus_tag="KRM55_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1593829.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            complement(25954..26730)
                     /locus_tag="KRM55_001581"
     CDS             complement(25954..26730)
                     /locus_tag="KRM55_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH1593830.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            complement(26835..27500)
                     /locus_tag="KRM55_001582"
     CDS             complement(26835..27500)
                     /locus_tag="KRM55_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBH1593831.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            complement(27500..28156)
                     /locus_tag="KRM55_001583"
     CDS             complement(27500..28156)
                     /locus_tag="KRM55_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBH1593832.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIIEGGNL
                     "
     gene            complement(28165..29343)
                     /locus_tag="KRM55_001584"
     CDS             complement(28165..29343)
                     /locus_tag="KRM55_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH1593833.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTITVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQSKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            29698..30600
                     /locus_tag="KRM55_001585"
     CDS             29698..30600
                     /locus_tag="KRM55_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1593834.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            complement(30816..31628)
                     /locus_tag="KRM55_001586"
     CDS             complement(30816..31628)
                     /locus_tag="KRM55_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593835.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(31631..32590)
                     /locus_tag="KRM55_001587"
     CDS             complement(31631..32590)
                     /locus_tag="KRM55_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593836.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            complement(32696..34255)
                     /locus_tag="KRM55_001588"
     CDS             complement(32696..34255)
                     /locus_tag="KRM55_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1593837.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            34474..35451
                     /locus_tag="KRM55_001589"
     CDS             34474..35451
                     /locus_tag="KRM55_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593838.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            35452..36423
                     /locus_tag="KRM55_001590"
     CDS             35452..36423
                     /locus_tag="KRM55_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBH1593839.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKKIKSVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            36575..38617
                     /locus_tag="KRM55_001591"
     CDS             36575..38617
                     /locus_tag="KRM55_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBH1593840.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNIMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVIKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATILLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            38878..39720
                     /locus_tag="KRM55_001592"
     CDS             38878..39720
                     /locus_tag="KRM55_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1593841.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
BASE COUNT        14713 a         4919 c         6450 g        13667 t
ORIGIN      
        1 aaagtaaaga tgaattacta taggtttaaa ttatattatt ttctattatt tttatgcctt
       61 tctcagttat tgatgagcct tttcttccct tactagaaat taagtatcca ttgcgtgtca
      121 aatattctag catatttctt acttcgtatt ctgtgacatt atattccata aatttcatta
      181 actttgtcct ccccattggt ttcatgtgca atgattttag gatagaaatg catatgtttt
      241 tgtcatattg gtttaaatca ttgaatatgg acatattact tgacatatga ttattattta
      301 attttgaaga tatgttttga ggtaaatcat ttattgtaag ataattggaa cccatgtaag
      361 ccatatattc aacacaattt ctcagttctc taatattccc catccaagtg tatgaattta
      421 aagcttctaa aagactctta tcgagtttta tgtttttata gggaagttct tttaaaaatg
      481 attctaaaag aagaggtata tcttctaatc tctttctaag aggaggtaaa tctaaagtga
      541 acatacttat cctataaaat aaatccatcc taaatttatt ttctataatt aatttctcta
      601 aatctttatt tgtggcagct aatattctca catcaattgg aataatactt gtaccaccaa
      661 tttttctaat ttctttttct tgtaagactc ttaaaagttt aacctgtaaa tcatgtggca
      721 tatctcctat ctcatctaaa aatatagtgc cagtatgagc taattcgaat aatccttttt
      781 ttccaccttt ttttgctcca gtaaaagaac catcttcata tccaaatagt tcactttcaa
      841 gtaattcact tggtaatgaa gcacaattta ttgctacaaa aggtttattt tttctatttg
      901 aatgattgtg tattgactga gtaaaggctt ctttacctgt tcctgtttca cctgttatta
      961 atataggatt atctgtaaga gccatttttt ttgccttttt aatacaatct tttataatag
     1021 aactatttcc aataatatta ttaaatttat atttagctac ataacctctt ttgacagaat
     1081 cacttcttat tttttgttct aatatttcta tattgtttac atcttttaat gtaattaagc
     1141 aaccctctat atttttataa agataaaatg gttttttaga aagtatgaat tttttatcta
     1201 tttcgtctat gtatataatc atattatcta tatttaagtt ctttgtaatt ttatctaaga
     1261 aactctttgg catatattcc attaaggaag gtgattttat aagtttttca tctagttcca
     1321 acatattaag taaagactta tttacaaaag taaccttatt aaaggtattg aaaaatatta
     1381 gaccatcacc tatttcatca atggtcatgt aaagtatagt ttttaattta gatatattat
     1441 ctaatgatgt atttaagaaa tcatgactta gtgtctcctt ggacaatttg tataattttt
     1501 ctataaattt ctcatttttt agttttaata ctactaataa tgacatatat gtatctaatg
     1561 agatttttct ccaacctaaa tcaacaatat tttttatgta ttttggtata aatctaatct
     1621 gacctggtgt tatagctgta tctaaatcat atatttcatc acaatctgga tatgtcggta
     1681 caaaatctat atgatttata ccaattttat atagataagt agccatctca aatgctgaag
     1741 ttttattggt tgtcataagt aacgattttg tacctggagg cagtttcatc attttttcat
     1801 atccaagttt tgaaagtgct ttcgttccat gaataatttc aatatcttcc ttaaaatgtt
     1861 ttattaaaaa attactagtt aaaggtgata gagaaagcac tacatctccc tctaaatttt
     1921 cttttattcc atcaagtata ttttgtgttt ctatgattat ttcgtctcca aaaaagtttg
     1981 ttaattcttc tttgtagtgg tcactattca atttatcata tgttataagg attaacttct
     2041 ttttatccat tttatttctc ctaacaaaat agtatttatt tttaaagtat ttaaagtata
     2101 aggcaagtta tattatacaa caaatagtag tataaattta tatatttgat taaataatag
     2161 gtttttttag gattttatcc tataaaaacc tattttgaaa ttatttttgc aagataagga
     2221 aaatagcttt ttatattgta atgtatattt taaataatta ataaaaaaat attatatttt
     2281 taaacttgaa aagtaagtaa ttataagcta tttaatcact ggaataaatt tacaataaaa
     2341 aaataaatac aaaggcttta tcattaaggt attggcataa gttttgctta ttaaacaagt
     2401 atactaataa aattcattta aacaggaggg agaatttata tgagtaaatt agaatcaaca
     2461 acagaaaaag ttgaggtaaa atggtatggg tatgtagcat taatattggg agcattattt
     2521 ttttcaggaa tatttaaaga tgcaccagga ccattaaaag tattggattt taacaatgta
     2581 ttaggttctt ttggaacatt gggaacaatt aatgatggtg taggtacatt agctgcaaac
     2641 tttagaggtg atggaggtac tggccctcga gatggatggc tatatgcatt gacattaata
     2701 ccatcagtta tgtttgcact tggagtagtt agagttatag accacttaga tggaatgaag
     2761 gcagctcaaa agcttcttag tccactatta aagccattat tagggttacc tggatttgca
     2821 ggactaactt tgatagctag tttacagtct acagatgcag ctgcatctat gactaaagaa
     2881 cttaaagatg atgggtatat agatgaaaaa caaaaagctg tattttgtgc atttcaattt
     2941 tcaggtgcgt ctgcaattac gaatttcttt gcttctggag cagcactatt tccatttata
     3001 ggagatgtac caatatttat accacttgct ttaatattaa ttatgaagtt tgttggggcg
     3061 aacttactta gattatattt aaataaattt gacaaggggg aagcttaaca tgagtgaggt
     3121 agcaaaaaaa gaagtaaaag ttaaaaaagg aaatgtgata gatgcgttta ttggaggagc
     3181 tagaaatgga ttccaaataa gtacaaattc aatggctcca aatgtcatct tcggttttgc
     3241 tataatttct gtgttcaact taacaggtct tttggatgta atagggacaa tatttacacc
     3301 tgtaatgagt atctttggac ttccaggtgt tgcagcaaca gctataatga caatatttat
     3361 atcaatggga ggagcatctg gagtaatcgc aggtttattt acagcaggtc aaataagtca
     3421 agcacatgtt gcaattctat tgccaatgtt attgctttca ggagcgcaga tacaatttat
     3481 ggggagactt ttaggaacag ctgagttaaa aactaaatat tatccacata tgtttgttat
     3541 agcaacttta aatggttgta ttgcaatgct tataatgaat tatttcgtag tataggtaat
     3601 tataataaaa atttaatata aatggaaagt ttaaatttta aggaggagct agattatggg
     3661 aactaacaaa gattatattg agtatgtaca taaagtgtat gattatctac acactatacc
     3721 agaaaaagga tttgaagaat ataagacatc agagtttgtt ttaaaagagc ttgaaaaaat
     3781 ggggtttgaa aatattaata aaggagttgc aggaactggt attatagtaa ctatagattc
     3841 taaaaaagaa ggaccagtat ttgctataag agcagatatg gatgcattgg aatttatcat
     3901 agatggagaa aagaaaatga tacatgcttg tggtcatgat ggtcatactt ctatgctttt
     3961 aacagctgca aagttaataa aagagagaaa tttagtaaaa agaggtaagt taaaaatact
     4021 ttttcaacca ggtgaagaaa aattatatgg agcattaaga gtaattgatt ctggtttgtt
     4081 ggatgatgta gaagaaatgg tagggatgca tttaagacct ggacaagatt gtaggttggg
     4141 aaaggcgata cctgcaatgt accattgtgc tagctgtata atggaattta cgattaaagg
     4201 tatcacttgt catggttcta aaccacattt aggagtaaat gcagtagatg ctgtctgttt
     4261 agcagtgaat gcaataaatg caataagagt aaatccagct ataccaaatt ctataaaagt
     4321 aacaaatata tcagttaagg gagaaactta taataatata ccagatgaag catttatggc
     4381 tttagatata agggcagaaa gtaatgatat aatagaagaa ttaaaagaaa aagcaataca
     4441 tgctgtaaaa actgttgtaa gttctataaa tgcagaagct gtactaattt ccaaagatgg
     4501 agtaccagca gcagaatttg atgaagaact tgtaaacttg gctgaagaaa ctataaaaga
     4561 tgtattggga gctgatgcat ctataggtat atttaaaaat tctggtggag aagacttcca
     4621 ttattataca caaaaactaa aatgtaaaac tacatatatt ggattaggag ctgatgctac
     4681 accaggattt cataatccaa atgtaacatt tgatacgaaa gctttagaat atggtgtaga
     4741 tatatggtgt agattggttg aaaagagatt gggataacat ccaaactaat aattctacat
     4801 ttaaaattat aattatagaa gttatagaaa aagattgctt atgttaatta gaaaataatt
     4861 aatatgagca atcttatttt gatataatga aactgatttt ggaatattga aaaaatatga
     4921 tggaaaagta attatatttt aaatctattg gacaaaaaag tgatattatt ataatattaa
     4981 gaattgtaaa ataataccaa agtgcatcta gtaatagact taacaattat aaaaatttta
     5041 ttcttaggag ggaaaaaatg agtaagtata attttgacag agtaatagat agagtaggaa
     5101 cagattgtgt aaaatgggat tttagaacta attgttcaac aaaagcacaa aaagatggtt
     5161 tgcctttttg gattgctgat atggattttg aatgtgcaga accaataata gaagcattac
     5221 gtaaaaaagt tgaacataaa atatttggat atagttcaaa tgatagtgat aaatacttta
     5281 atgcagtttg tgattggtat aaaaggagat ttaactggga aataagtaga aaagatatta
     5341 tttttagtcc tggtgttgta cctgctgttg ctattttagt aagaatatta actaattcta
     5401 atgaaggtgt aatagtccaa aaaccagtgt attacccatt tgaagctaag ataaagagca
     5461 ataataggga cgttgtaaac aatcctctga tatatgagaa tggtacttat aggatggatt
     5521 atgatgattt agaagaaaaa gctaagtgta gcaacaataa agtactaata ctttgtagtc
     5581 ctcacaaccc tgttggaaga gtttggagag aagatgaatt aaaaaaggtt gtagaaatat
     5641 gtaaaaaata tgacctatgg ataatagctg atgagataca ttctgattta attagaaaag
     5701 gatttaaaca tactccttta cagtcattat gcccagagta caaggataaa atagttacat
     5761 gtatagctcc aagtaaaaca tttaatctgg caggaatgca gttgtctaat ataatagtga
     5821 ataatgatga actaaaaaag aaatatcaag aagaggttac agctgttgga gttgcaactt
     5881 caccaaatcc ctttgctatt gtagctacaa tagcagcata taatgaaagt gaagactggc
     5941 ttaatgaatt aaatgattac ttagataata atatacaatt tattgatgaa tacttaaaag
     6001 aaaacctacc aaaagtaaaa cttgtttatc cagaaggaac atatctagca tggttagatt
     6061 ttactgctta tggattaaat gaagtagaac ttgaagattt aatgtttaaa aaagctaatg
     6121 tattatttga tgaaggttat atatttggaa aagaaggaat aggatttgaa agaataaatg
     6181 tagcttgtcc acagtcttta ttaaaagaat gtatggacag attaaagact atatttgaaa
     6241 atttataaag tataggtaaa aatttataaa gtgtttaaaa ataaaaaaat aataaacttg
     6301 acaaatttta actaatcact tatcatacta ttatgaataa atagaaaaca taagagagct
     6361 aaattttatt gaattaaact cttaaagact ttgaaaggaa gagtagttat agaatgtaat
     6421 taaagcgagt tggtgatggt gtgagaccaa tatgaagtct atagtgaaga acatcctgga
     6481 gttgctaacc gaaattttaa aagagtaggc ttagtcggaa ccaaaccgtt atcatattgg
     6541 ggtgtatcga gtaatatctg tacattgtga gctgggtttg aatttatttc aaactaatca
     6601 gggtggtacc gcggaaaagc aacctttcgt cccttttata tagggatgaa gggttttttt
     6661 aatggaaaaa tatataaata tagggagtga atgatatgag cacaataata ccaaaggatt
     6721 ataaaagtag tttgaacgta attgatacac aaatagctat aaaaaaatta aaagattttt
     6781 ttgaaatgag actaagtaat gaattaaatc ttataagagt ttcttctccg ttatttgtat
     6841 tgccagaaac aggtgcaaat gataatttaa atggagaaaa ggctgtaagc tttgatatac
     6901 catttatgaa taaaaatgca gaaattgttc aatcacttgc aaaatggaaa agattagccc
     6961 ttaaaaaata tgggtttgaa gttggtagtg gtttatatac agatatgaat gcaataagaa
     7021 aaaatgaaga attagacaat atacattctc tttatgtaga ccaatgggat tgggaattgg
     7081 ttatagataa aagtagtaga aatgaaaaga ctctaaaaga tgttgtaaaa agattgtatg
     7141 gagtatttaa agatactgaa atttttgtat gtagtatgta tgaaggtata aaagaaatat
     7201 taccagaaga aataactttt ataacatcac aagagttaga agatatgtat ccagaattat
     7261 caccaaagga aagagaagat aaaattgtaa aagagaagaa agcagtattt ataactcaaa
     7321 taggaaaaac attaatatca ggagaaaaac atgatggaag aagtcctgat tatgatgatt
     7381 gggaattgaa tggggatata ttattttaca atcctgtttt agattcagca ttagaattat
     7441 cttcaatggg aattagagtt gatgaagaat ctcttgatag acaattgaaa cttgctggat
     7501 gtgaagagag aaaagagttt gactatcata agatgctttt aaatggcgaa cttccgtata
     7561 caattggtgg aggaattggt cagtcaagaa tatgtatgta tttcttacaa aaagctcata
     7621 taggagaagt acaagttgga gtatggccac aggatatgat tcaaaattgt agtagtgcag
     7681 gaattgaatt attataattt aaatataaac taattgataa aatttatatc taatatgttc
     7741 atcaaattaa ttatatcggt tataatgtag aataacctat aattataaga ggtgataaat
     7801 atggagtttt taaaaataat cattaatata gttttagata ttttaaaaaa aattttggtc
     7861 agatttaaaa atgctaaatt tggtttggtt tttgtatttg atttacttaa actacctgat
     7921 tttatgacag ataaaagaat caatatagtt gataaaataa aggtaatttc tgtattaatt
     7981 tttactatat cctactttgt atctggggtt gatataattc cagagatgat tgcaggggca
     8041 tttggtttta tagatgatgc tatagtttta atttggagta taggtatagt gaatgaagaa
     8101 attaataagt atagagttat cgcaaaaaaa gataaacatt caaatataat tgaaaatgta
     8161 gaattttcta taaaagatga agaagaataa caatttatat atgttattct tttttttatt
     8221 aacaaaaaat ggttaaattg ttgacggaga ggtaaaactc tattatcata ataagtggat
     8281 atccaatatt taactaagta ttcaatgtgc aagaatgctt aatttaaaaa agttatggag
     8341 ggtaaatatt atgaagaaaa aaataggttt agtgcccaaa ctaatcatcg gtatcatagt
     8401 cggtatttta atcggaagtt atgcaccaga aataatagta caaatattag taacagttag
     8461 tactttattc tcagcattcc taaaatttgt tataccattt ataattatag gttttgtaac
     8521 agcaggtata gctgatttag caacaggtgc aggaaagtta ttggggataa ctacgggaat
     8581 agcatatggt tctaccttaa tagcaggatt attatcattt gcagtatcta cattaatctt
     8641 cccaaatttt attgatgcaa gtgttgcaag tcaaattgga gacccagagg caggaatgtt
     8701 agctccaata ttcacaattc cattagagcc tatggtagat gtaacagctg caatcgtatt
     8761 tgcatttgta atgggacttg gaatatcagc tttaagaaat catggaaaag gagagacttt
     8821 atttaatttc ttccaagaat ttcaaggaat cgtaacgaaa acgttgtcaa cagtgattat
     8881 acctttatta cctttataca tagcaggaac ttttgcaaat ataactatag caggggaagt
     8941 atggacaata ttaggggtat tctggaaagt atacttagta gtaatacctt tacattttgt
     9001 atatatggca tgtcaattca cagcagcagg tgtattttca ggaaaaaatc cagtaagaat
     9061 gttaaaaaat caagtacctg gatatttaac agctatagga actcaatctt cagcagcaac
     9121 tataccagtt aatgttggtt gtgcagaaaa aaatggagta agtaagcaaa taagagaatt
     9181 tgttgtacct ctttgtgcaa caatacattt atcaggtagt atgatatcaa taacaggatt
     9241 tacaactgca gttttaatga tgaatggtat gccacatgga ataggtgtat tattccctta
     9301 tattgcaatg ttaggtatag caatggttgc agcaccagga gcaccaggtg gggctataat
     9361 gagtgcactt cctttcctac caatggttgg aataccatca gatggtgggc ttgcaagttt
     9421 aatgatagct ttatacttaa ctcaagacag ttttggtaca gcatgtaatg tatcaggaga
     9481 taatgcaata gcagtagtag tagataaaat aaatgatgga atgagtaaaa aaggaaataa
     9541 agaagagcaa agtgcttagt tttttaataa tcaaaaatga gttatctcaa atagagatag
     9601 ctcatttttt atggtataaa aaattataaa ataaagtgat ttttttattt aaaaattgct
     9661 ttaagagatg atattaataa tttattttca ttaggtttta atatacatat tctaaagaaa
     9721 tactcatcta gaccttcaaa tgaacaacaa tctcttatta ttattttttg tggaagcagt
     9781 tgctctcgaa gagatttagc agtcaattcc tttgtcttga ttttacacaa tatgaaatta
     9841 cctttagtat tgtatatatc taagcttttt atattcttaa gctctttaag caggtaatct
     9901 ctttcagtgt tcattaagga aatagtattt gatataaaat ctaaatcact aaacatgatt
     9961 tcacccattt tagaagctat tatgtttata ttccataaat ctagattttt atttatttca
    10021 tttttgacat tagtgttaga tataagacca tatccaagcc ttattccagg cgttgaaaaa
    10081 aattttgatg tacctcttat aacgaataaa ttagaataat catcaactaa ttgagtacaa
    10141 gagtatgtat ctgtatcagt aaactctaca taagtctcat caatcattaa aaatgagtct
    10201 gtatttttta aaatttcttt cacttctact ttagtaaatg caaatccagt tggattacta
    10261 ggattacaga ttactaccaa atcataatct ttagcattga tagtttttat aagattttct
    10321 aaatttatat gaaaattatc ttcttctttt gcaaagtatt tttctataga acaattaatt
    10381 ttagataact ctttttcata ctctgaatag gctggagaga gtaaaagagc ctgtttaggg
    10441 ttaattgtat gtataaatga tgaaattagt tctgtagctc cactgccaag tactatatta
    10501 tctatagaac atttgcagta attggatata gaagttttta agtctatgta atcagggtca
    10561 ggatacatag ataccatatc tatattgttt acaatgtatt gtttggctaa acttgatgta
    10621 ccaaaaggat ttatatttga gctaaaatcc ataaattctt cctttgaaaa gccatactta
    10681 ctagataaac tatataaatt agctccatgg tttgtgctca taaaagtacc tccaaaaata
    10741 aaattatata atcgataaaa ataactgatt aatatatgta catatagatt ataatacaaa
    10801 ggaatcgtta ttccaaattt ttaatggaaa aagcaaaaaa gtatggataa gctgttaatt
    10861 taggtttaaa aatgatgaaa aagattttaa ttgatatttt ggtatgctat aatatataag
    10921 ttaatagaag gaaagcggga ggatacaaaa tgtacaaagt tacaggaaaa atgttgacag
    10981 aagaacaaat aaaagaaaaa gtttatgaat taggaaaaaa gatagaagaa gactttaaag
    11041 gcgaagattt actagtggta ggtatactta aaggagctag tgtatttgtt tcagatttaa
    11101 taagatgtat agatttggat gtaaatatag attttatgag tgttacaagt tatggaaact
    11161 caacagagtc ttctggaaca gttaaaatat taaaagattt agatgtagat attgaaggaa
    11221 agaatgtgtt gattgtagag gatataatag attctggttt aacattaagt aatctagttg
    11281 cagctttaaa aactagaaat ccaaaatctt taaaactatg tactctactt gacaaacctc
    11341 agagaagaaa agctaatata cctgtagact atgttggatt tgttatagaa gacaaattta
    11401 ttgttggtta tggaatagac tatgctgaaa agtatagaaa tttaccttat ataggtatag
    11461 ttgaggatgt agaatagatt taaatgtgaa tcaaaagcac taatttctaa gggagttagt
    11521 gctttttagt taattatata aaattttagt aaaggagaca tctatatgga tattcagtta
    11581 aatatattat tatttttcca aaatttaaga aatccaattt tgaactttat atttcttgtc
    11641 tttacaataa gcacagaagc accgttatta atattaatta caacaattat atactggtgt
    11701 ataaataaaa aatgtggaca gaaaatactg tttgctataa ttggaaattt tgttgtaaat
    11761 ttaggcatca aagagtttgt aaaagctccc agaccaatag gaataaaagg tcttgaatca
    11821 ttgagagttt ctactgctgg tggttattct tttccaagtg ctcatactca aactgcaaca
    11881 acattttggg ttagtattat gactatattt aaaaagagat atcttcattt aataggtgca
    11941 gttatggttt taggagtagg attgtctagg ctgtatttag ctgttcattg gccaatagat
    12001 gtgatagcgg gttggatatt aggaatattt tttacagttg tatttgtaaa aatatttgac
    12061 tatattgatg ataataaaaa ttatatttta cttgtagttt tacttatacc atttataata
    12121 gtggctatat ttctaaatag ccctgaatat tttgaaaaat ttggtataat agtaggattt
    12181 gtatttggat atatggttga ggatagattt gttaaattta atacagataa taataacaaa
    12241 aaaataaatt ttagtaataa aaataagggg agtaaaaata taattttttc aagaatatgt
    12301 aggttttcgg ttgggatagt aacaatagga atgttatata ttggcattaa gttgtttatt
    12361 tcaatgttaa tagtcacttt aaatataagt gactctacta tgagtataat ttttatgaat
    12421 tttattaaga atacagtagt tgttttttat ggaatagcag gagctccagc attatttaaa
    12481 cttttaaaat taaattgatt ttaaggtata gagtcaatag tttaaattaa aaaaattaag
    12541 ggtagaaaag agtgattatt tgaagaaggt agtaataata ggtggtggac cagcagggat
    12601 gatagccgca tcaactgcat gtgagaaagg ctatgatgta acattaattg agaaaaatca
    12661 taaattagga aaaaaacttg caataacagg aaaaggtaga tgtaatatta ctaacgcttg
    12721 tgaaatagag gaattaatag aaaatgtacc tacaaatgga aaatttcttt atagtgcttt
    12781 ttatactttt acaaatgatg atgtaataag tatgtttaat aatcttggag taaagactaa
    12841 aacagaaaga ggaaaaaggg tttttccaga gagtgataaa gcatttgata ttgtaaatgc
    12901 tcttgaaaga caacttaaaa gtaagaaagt aaatatatta ttaaattcga aagtagaaaa
    12961 aataatatct aaaaataata aaattgaaaa agtaatttta aacgataaaa aagaaattaa
    13021 gtgtgattca gttgtagtag caactggtgg attaagttat ccacttactg gttctactgg
    13081 tgatggatat aaatttgcaa tttcacaggg gcacacaatt atagatacaa aaccatcttt
    13141 aattggtata gaagtacaag aaagttttac aaaagattta gaaaaattat cattgagaaa
    13201 tgttgaaata agggtgttta atagcaaaca aaagaaagtt tatagtgatt ttggagaact
    13261 tgaatttact aaatttggtt tagatggacc tataatcaag tctgcaagtt gtagaatgaa
    13321 agatacaagg aaagaaaatt acactatatt attagattta aaacctgcat tagatgagga
    13381 aaaattggat aaaagagttc aaaaagattt tcagaagtat acaaataaaa aatttgaaaa
    13441 agcattagat gatttacttc caaaaaaact aatacctata ataataaact taagtgaaat
    13501 taatccaaat acggttgttc accaaatttc tagagagcag agaaaaaact tagtccattt
    13561 attaaaaaat ttaaagttta cagtaaagag atacagacct attgaagaag ctataataac
    13621 ttctggtggt gtaaaagtaa acgaaataaa ttcaagtaca atggaatcaa aattagtaga
    13681 aggtttattt tttgctggag aagtaataga tatagatgca tatacaggtg gattcaattt
    13741 gcaaatagct ttttctactg gatatttggc aggttttaat tgctaaaaat tacctgaatt
    13801 aaaaatgttt aaaatcacat aatattatca gcaacacaaa ataaattaaa cagaaggaag
    13861 gtaatcaaca tggcaagtaa caataacaac aacagaacag tagtaccagg agcaaaagag
    13921 gctttaaacc aaatgaaatt agaaatagct aatgaacttg gtatgagtaa ttatcaacaa
    13981 gttgataaag gaaaccttac tgcaagagaa aatggttatg taggtggata catgactaaa
    14041 aaattagttg aaatggctga acaacaaatg gctggaaaaa gcaacagata gttataaata
    14101 attatttata actattggct attagtttag ctagagctat ctcaaatata gaaagtaatt
    14161 tctaaattga gatagctttt ttttattaaa ttattaaata gatatatttt tatgtaataa
    14221 attttatgta tttggataaa ataatacaaa tgaatatgtt acataaggag tgatgtaaaa
    14281 tgagtagtgt aaattttgag gatttaaaaa acaaatttat taatagtgac ttagatgaaa
    14341 aaataagaat atatacaaca acagaaggtt tatcagtaga acaatttaaa gagctactaa
    14401 aatattatcc aatacaacat ttatctaaac tagaaaaagc acttggatag cagtatttaa
    14461 tccaaaatta aaaaggcaat ttatttaata ttaaaaatat tttttattaa ataaattgcc
    14521 tttttataat aggtttaaat tattatgctt ttgatatata attatagatt ctctcatttc
    14581 caagttcaat agacccagta ttaataagag taactattcc ttctatatct ctagcagtta
    14641 agtatttata tggaattaat aaattataac cagtattact tagtaagttt tttaattggg
    14701 ttatttgaga gatattgaaa cattttgcag ttttagtaga tttttttctt aagttagata
    14761 aattttcatt ttgaatattt attaaagttt ctatatagtt tctataagat atcttaaagt
    14821 ttgtctcatt gactattttt tcattaagta tactactgat aaaatcttga gacaatatat
    14881 tatctgcaaa tttatctgct gttaattttc cagatgttat gcctttttga tattttctaa
    14941 gaattttttt agtatagcag tatattttat ttctcgtttc taaatcgagt tgttctattt
    15001 gcacaaaacc acttccttct aattataaaa atatttatta aaaatctata cttaactaat
    15061 aaagcttcaa taacttattt acaataaata ctaaatcata aaatatttgt tattttttat
    15121 tattaccaag tataaaaaat attataattg taaaacttac aaatatatgt aaaatattta
    15181 ggagtgatga aaatgttaaa tgggataata aagctttttt attctgaaat tgtaaaaaca
    15241 aagattaata acttagattc aagtggatat tctttaagag atgaatgtaa agaaatcaga
    15301 aatataactc taaagataga tagtgtattt tttaagcttt taaagttagc ttttggttca
    15361 atattgctta tggtagcttt taatttaaac atggttttag gtataggagt gtttttagtt
    15421 ggtgtagttt atatactata taaaagaaat atggaagaac aagtaaaaga gcatataaat
    15481 aatgtgaaaa ataatatcga catctctaaa ataactttta tggatgaaaa agggagaaca
    15541 ggtctaaatg cattaattac attacttctt ataggattat tgacaggatt taactggata
    15601 ttagttgcta gttttgtcgt tgtttttgtt tttactataa agaatgtatg ttaaaatact
    15661 aataaatagt ttaatatata gggggagaaa ttgagtatga ctaatggcag ttataaaatg
    15721 aagaatttag tggaaatatc cgctatggtg actgaatcta cagatttttt taatataaaa
    15781 gatgacataa tagaaaaaat gttagaagtt gttcacccta caaaggcatg tgtgaatcta
    15841 ttttataaaa atgattctaa atatgcctac ttagtatgtt cgcaaacctt agaatatgta
    15901 cctcaaattt ttccaataaa tagtcttaaa ggtgcaaaaa ttgattttga cacatatcca
    15961 gagtatatac atgaggctgt aaatgaaaaa aaaataatat atgtggaaaa tgtatttgaa
    16021 gattctagag cagaaggtga acgagattta gcaaaagctg aaggttatat tgggagaata
    16081 gtttttcctt ttataataaa taacgtagtt gttggattta tgacttgttt tttaaaagag
    16141 gatgattata taacagaaca agatatagat tttatatcat ctgttgcatc actcttaagt
    16201 ttatcaatag aaataactaa taaaaataat aatgtacaaa ttttaattga taaactaaga
    16261 ggctcaataa gtgccataaa tgaagctact aaaaaactat accttaataa gagtattgat
    16321 ggatttttgg aaaatttaag taaacaagcg tgtaatatta ctaatagtaa agaagcttta
    16381 ataattataa atagtcatca taataaggat gctatagtta gttgttataa tgttgagcaa
    16441 aaaaagaaaa caaatttata tcctatgatt gatatgtttt taaagaaaga gtcattgggg
    16501 gggtatttaa ataatttaaa accatgctca aaaaagggaa taaatttgga aagttatata
    16561 tattacaaac ttcaggataa aaatgagact ataggatgta tagtttgtgc aaatagcaaa
    16621 aactatacta gtgatgattt aaatattctt agtatattgt ccaaacaagt ttctgttggt
    16681 atgcaattat atgaacataa tgaaaaggaa gtaaaacaca aagttcttga aaacgagttg
    16741 aacatattaa ataaacaaca acagcttatt atggataaag gtaaaatgga ttgtaatgat
    16801 gagaaagaac tttattttta ccataaacca gcaagggtag taggtggaga tttttattat
    16861 gctacaaaag tggatgatga acatatagtt tatattgttg ctgatgtaat gggacatgga
    16921 atggtatcaa attatgttgt tgcaatgata aaaggtgctt ttaaagtatt atgcaatcaa
    16981 tacaatacac caagagaaat aatgacaaat ttaaatagga tgttatatga tgaatttgac
    17041 aagatgggag tatttacaac ttgtttgata ggtattatag atactaaaga aaatatgatt
    17101 actgtgtcta atgcaggtca ctatagtcct gtagttgtaa agaaagatgg cacaatagaa
    17161 aataatttaa attgtaaaaa gggcatacct attggaataa tggaagatgc tacttatgaa
    17221 aataatactc tttcaatgga agattatgca atggtatgta tgtacactga tggaatttta
    17281 gagataaaaa attcatcaaa agaagagtat ggtataaaca gattagaaaa ctttctaaaa
    17341 gaaaatttta gattaaatca acagttaata gtagaaaatc taaaattgga tttaaagaac
    17401 ttctcatcaa aagataatta tgatgatgat attttaatag ttatgttaaa ggataggtag
    17461 attgattatg gattcaaacg ataaaaaagg acttaaaagt ccagagatta taataataaa
    17521 tggaagtcca agaattaata aaaattgcag ttttatagca aatgaagtaa aagctatgct
    17581 agaagagtgt ggattaagtt gtaaaatatt taatatctac aatatggata ttgaatattg
    17641 cacagcatgt ggattttgtg aaaaaacagg gtattgcaag tttaatgatg atatgaagcc
    17701 attatataaa atgtttgatg attcaaaagg aactatagta ataagtcctg tacattttga
    17761 ttcaatatca gctaaattaa agactgttgt tgatagaact caagctatat atgcaagtaa
    17821 atatgtatta aataaacctt caattgatag aagtaagaaa cggataggaa tgtatattgc
    17881 agtgggaggg agtaaatcat atgattcaca gtttaaaggt ggacagattg ttatggattt
    17941 tttctttaag agtataaata ctaaactttt acacaatata tatttaaaca atacagatga
    18001 tgtatcttat atagataatc aagaatttaa agatataata tataaaaatt taaagatata
    18061 tattgattca atataatttg attttgtagg taatattatg tataattgta ttgcaataat
    18121 ttaaataatt aaaaggaggg aatttcaatg aaattaccaa tagcattatc taataaacat
    18181 gttcatttga gtcaagctga tatagacgta ttatttggag caggtcatga gttaactaaa
    18241 tttaaaccat tatctcaacc agggcaatat gcctgtgaag aaaaagtgga tttagtagga
    18301 ccaaaaggaa ctttaaaagg agttagagta ctaggaccag ctagagctca tactcaagtt
    18361 gaaatatctt tagcagatgg tttcccatta ggagtaaaag caccaataaa agaatctggt
    18421 gatatagctg gaactccagg tgttaaatta gtaggacctg ctggagaagt tgaaatgaaa
    18481 gaaggagtta tagttgcttc tagacatata catatgagca atgaagatgc tgctaaattt
    18541 ggtgtaactg ataagcaaat agtaaaagtt aaaacatctg gaccaagagc attagtattt
    18601 gaaaatgtat tagtaagagc tagtgacagc tttaatctag aaatgcatgt tgatatggaa
    18661 gagggaaatg cagcaggcgt taaaaatgga gatttagtag aattaatagt tgattaatat
    18721 tataaataga ctttatgcta gtagatattt tatttgctag catattttta aatgtaataa
    18781 atttctatag gataaattta atcaattaga ttaatttata aaataaaggg gtattataaa
    18841 aaatgtaata aaaacttaca aaaatatgat gtaatatggt aaaattatat atataaaaat
    18901 ttacatgtaa taaggataag cattttactt tttatactaa tatgaacaaa tagataaaaa
    18961 agtttgaaaa atctaactta atttattata tattgtatac aaaattatga aaaaaactta
    19021 acatatttaa ttttaaaaaa aatctactta aatatgtaat taatttacaa ttttcaaagg
    19081 aattttatct aatctgtagt attatattag aagatagagt atttgcgcga ctatatgtgt
    19141 gtttatagtt ttgttgtgta aattatatgt aaatataaaa aaatagactt gttataaaca
    19201 agtacaattg tagctatcaa ggaggataca tattatggct aagtttatga aaacacttga
    19261 tggaaataca gctgcagctc atgttgccta tgcgtttaca gatgtagcag ctatatatcc
    19321 aatcacacca tcttcaacta tggctgaagt agttgatgag tgggcatcac aaggaagaaa
    19381 aaatatattt ggacaaacag ttaatgttgt tgaaatgcag tcagaagcag gtgcatcagg
    19441 aacattccac ggttctttac aaggaggagc tttaacttct acttttacag catctcaagg
    19501 tttattatta atgataccta acatgtataa agttgcagga gagttgttac caggagtatt
    19561 ccatgtaagt gctcgtgctt tagcatctca agctttatca atatttgggg atcaccaaga
    19621 cgttatggct gctagacaaa ctggatgtgt attattagct tctggttcag ttcaagaagt
    19681 agctgatata gcacctgttg cacatttagc tgcaatagaa ggtagattac catttataca
    19741 tttctttgat ggattcagaa cttcacatga aatccaaaaa gttgaattac tagaaaatga
    19801 agattatgca agtttattaa actttgaagc agttcaagca tttagagata atgctttatc
    19861 tccaaatcat ccagttgctc gtggtactgc tcaaaaccca gatatatatt tccaaactag
    19921 agaagcttct aataaatact atcaaaatat agtaggtata gttgaaaaat acatggaaaa
    19981 aatgagtaat ttaacaggta gaaaacatag tttatttgat tactatggag cagaagatgc
    20041 taaatacgta ttaatagcta tgggttcagt aacagaaaca atagaagaaa ctatagatta
    20101 cttaaatgct aagggagaaa aatatggttt agttaaagtt catttatata gaccattctc
    20161 aatgaaacat ttcttagatg ctatgccatc tactgttgaa agaatatgtg tacttgatag
    20221 aactaaagag ccaggttcaa ctggtgaacc attatactta gatgtacgtg atgtattcta
    20281 tggaaaagaa aatgctccta tgataatagg tggaagatac ggattaggtt caaaagatac
    20341 tactccttca gatataaaaa ctgtttttga taacttagtt tcagaacaac ctaaaaatgg
    20401 atttacagta ggtatagttg atgatgtaac taatacttct ttaactccat ctgagccaat
    20461 aaaaatagct tctaaaggaa ctataagatg taagttctgg ggattaggtt ctgacggtac
    20521 tgttggagct aataaacaag ctatcaaaat aatcggtgac catactgaaa aatatgctca
    20581 agcttacttt gattatgact ctaaaaaatc tggtggtata actatgtctc acttaagatt
    20641 tggtgatact ccaataagag ctacttattt aatagatgaa gctgattata ttgcctgtca
    20701 taaacaatca tatgtttatc aatatgattt attaaaaggt cttaaaaaag gtggtacatt
    20761 tgtacttaac actatatggg accaagcagg acttgaagaa catttaccag ctcatatgaa
    20821 acaatatata gctaaaaatg atataaaatt ctatacagtt aacgctgtta aactaggaca
    20881 agaaataggt cttggaaaca gaataaacat gataatgcaa tctgcattct ttaaattagc
    20941 tgaaataata ccagaagaag atgctgttaa atacttaaaa gattctatag ttaaagctta
    21001 tggtaaaaaa ggtgaaaaaa tagttaacat gaactatgct gctgttgatg caggaataaa
    21061 tgctttagtt aaagttgaag ttccagcttc ttgggaaaat gctgttgatg cagataaagg
    21121 agaagttaaa gaaccagaat ttataaaaaa tatactaaga ccaatgactg cacaagaagg
    21181 aaacaactta ccagtaagta cattcaatgg tatagaagat ggaacattcc cttgtggtac
    21241 tgcagcttat gaaaaacgtg gtatagctgt tgatgttcct gaatggataa tagataactg
    21301 tattcaatgt aaccaatgtt cttttatatg tcctcattca tgtataagac cagtattagt
    21361 tactgaagaa gaattagcta atgctccaga aggatttgaa gctaaaaaag cattaggtaa
    21421 aggattagaa ggattaaaat atagaatgca acttagtcca cttgactgta caggatgtgg
    21481 aaactgtgct gacatatgtc cagctaaaga aaaagcttta gttatgaagc caatagatac
    21541 tcaacttgat acagagttag ataattgggc atttgcagta aatcctgatg aggtagctcc
    21601 aaaaggtgat gttatgcctg caaacactgt taaaggaagt caatttagac aaccattaat
    21661 ggagttttca ggagcatgtg ctggatgtgg agaaactgca tacattaaag tagttacaca
    21721 attatatgga gatagaatga tgatagctaa tgctactgga tgttcttcta tatggggagc
    21781 ttctgcacca tcaattcctt atacttgtaa ccatgaaggt aaaggtccat cttgggcaaa
    21841 ctctttattc gaggataatg ctgaatatgg atttggtatg tacacagctg ttaagcaaat
    21901 aagaaataaa atagtagatg ctatgacaga gttagtttct atggatatct gtgaagatgc
    21961 taaagcggta tttacagagt ggttagattc tagaaatgat ggagaagctt ctaaagtagc
    22021 aagtgctaag gttgttgaat tattagaaaa accagcttgt gattgtacag atgaaaaagc
    22081 taaagagtta gtaaaagcta taaaagatag aaaagattat ctagttaaga gatctcaatg
    22141 gatactaggt ggagacggtt gggcatatga tatcggttac ggtggattag accatgttct
    22201 tgcatctggt gaagatgtaa acgtacttgt atttgataca gaagtatatt caaatacagg
    22261 aggtcaagct tctaaagcta ctccagctgc tgctatggct aagtttgctg cttcaggtaa
    22321 aaaatctaga aagaaagatt taggaatgat ggctatgaca tatggaaacg tatatgtagc
    22381 tcaagttgct atgggtgctg ataaaaacca atttatcaaa gccgttatag aagctgaaaa
    22441 acatgatggg ccatctttaa taatagctta tgctccatgt ataaaccatg gattaaaaga
    22501 aggtatggga agaactgtag ctaacgaagc acaagctgtt gcttgcggat actggcattt
    22561 atacagattc aatccagaag taaaagctga aggtaaaaac ccattcactt tagattcaaa
    22621 agaaccaact gcaagcttca aagatttcat acttgcacaa gtaagatatt ctgctatagc
    22681 taaacaattc ccagaggaag ctgatggatt atttgctaaa gctgaagctg atgctaaaga
    22741 aagatatgaa ggatacaaaa aattagctga ataatattaa agtattataa tgcttatata
    22801 gaattgataa aagagagtgt ctcaaagtga gctttttagt tcatgaggca ctctttttgt
    22861 atgaaatcaa atatatttta atcatttcaa caatgaaaaa ggccttatct ctattttgag
    22921 acagcctttt tttatgaaga tattaagatc ctgtttttac ctattaaata tctttttaag
    22981 ttttccattt tcatcttgcc aatacttttt atatattgct ctacacacta aaattaagag
    23041 aacaaataat atttatagta tgtatatttg gatttgataa ttttaaaata gatacaaaag
    23101 agtatctcat ttgtgttttt tatcacttag agataatctt ttgatatgta tggaaaaaga
    23161 ttattttatc ctacaaagat ttgtgtccaa taaattgaac caccactttt ttgtgctact
    23221 ccaacaccta ttttactgaa atttggattc attatatttt ttctgtgacc ttcagaattc
    23281 atccatgcat ttacaacttc tttaggagtt ttttgaccca tagctatatt ttcacctgct
    23341 gtcttatagc ttattccaaa ttttttcaac atgtcaaatg gagaaccata agttggagaa
    23401 ttgtgtgaaa aatagttgtt atcaatcata tcttgagatt tttttgtagc aacatttgat
    23461 atagaagaat caagagtaag aggatttaat ccagctttag ctctttctat atttactaag
    23521 tcaacaactt ctttttggta agctgaaaaa ctttcacttg tagagcctga gttgttatta
    23581 tcatcaggtt tgttagtaga gtctgaatta ttgttgtctt caggtttatc agtagagcct
    23641 gaattattgt tgtcttcagg tttattagac tcaggtttat tattatcagg tttattagta
    23701 gagcctgaat tattgttgtc ttcaggttta ttagactcag gtttattgtt accaggctta
    23761 ttagtagagt ctgaattatt gttgtcctca ggtttattag tgttgttgca attcttgtca
    23821 ttatgattct tatccttaca agagttatct ttatcaggct taagttctgg ttttacagaa
    23881 caatttggtt ttgcagaaaa cttgtattta gtattactat atactaaact tttgttactt
    23941 atatttacat tattttcaag tgatgaagca cttgcagtaa cagcacttga agctgttgct
    24001 aaagttaaca ctcctaaagc taatatagtt tttaattttg ttggtatatt tcttctcatc
    24061 attaaacacc tcttaatcta aaaattctaa aaatgttact gatttgtaac ctttagtgta
    24121 gggggttacc cgtgaatcta tactaacata agattaagac tttttttact gtaaagatat
    24181 gtaaaaaaga tatatatgga ataaataggt atatttcagt gtgtttgaca atttgtatta
    24241 aaagcctgta tagtatggaa ttacttagtt agagaaaata atatttttat aataattcca
    24301 taacgtaaat ttatagttat gataaatttt tttttatttg gttaaattta ttcagtagat
    24361 gctttcgtat tagcaacaaa ttataattat ttaaatcttt aagaaataaa aagggtctgt
    24421 ctcaaaatag agataaggcc ttttttattg tttaaatgat aggcatatgt tatttcatat
    24481 aaaaagagtg tctcattaag taaaaagttc actttgagac accacctttc atattatgaa
    24541 ttttaatttg ttttatatta atacattagt aatcctaatg taattacaat aatttctgct
    24601 attagtgaac caactgcaac tacaatgaaa gtttctttaa atccagtttt atgtgttaac
    24661 ttagataagc ttaagaatgt aagaaaaaca ccactttgtg gaactatagt tagtatattt
    24721 gaagctattg tagcaacacg gtgaattaat tctggattta gaccagtact taaataataa
    24781 tctgcaaagt ttggcattac tattcctaat gcaccagaag aggaccctgt tattgctgac
    24841 attgttgaag tcaaaacagt aagacttata agtggactac ctggtattga cattataagt
    24901 ttgctaaata catcaaaacc aggtgcagcc attattactg ctccaaatgc aactgcagaa
    24961 gatgtagcaa atataggacc tatagaacca ctagcaccta tgctcaatgt ctgtatctta
    25021 gatgatagaa atttatggaa taaaaaagca gataaaagaa ttgcaactat taaagctatg
    25081 taaattacat tttttttcat aaattctgaa ccaaaagtac ttccagttat agctataatt
    25141 acgagtgcta atagaggaaa aatacttgca aaaaatcctg gtaattctct atctaaagat
    25201 tcttcttcta attctgaagt ataagttgca taagtttcac cttttctaat acttttgttt
    25261 agagcatatt tcatatagac aagtccaaac gtagcacaac ctatactacc tacaatactt
    25321 ggtatagtag ctgcagtaag agacgtattt agatattgaa taggtataac attttgaatg
    25381 gctggtgttc caggaattat agtcatagta attgttgcaa taccaagcca aagtggtatc
    25441 tgaataaggt tccaagaaat atcaagtttt ttaaatagag ttcttgcaag tggaatgacc
    25501 gcaaacataa ctacaaataa gcttatacca ccatacgtta atataaaact tactataaat
    25561 atagcaacta aaactctata aggatgatta gagccaaatt tatttaaaat aaaatcagct
    25621 attgatacag tagctccact ttcttccata aatttagcaa gtattgagcc taataagaat
    25681 attgcaaaat aactcattat atagtttcca agtgcaccca tataattgtt tttgtcagca
    25741 cctagcattg atgttacaac atccatttta tttaaaataa caactattaa agttgctatt
    25801 ggagcagcta tagttatatg aatttcttta actgaaaaat atataatagc tatgatacca
    25861 ataattatac caattggtgc gataatactc ataaatatcc ctccttagta gaaggacctg
    25921 aagaatactt tcttcaagcc ctaaatataa taactattgt gcagtatatc ctccatctag
    25981 taagcaagct tgtcctgtaa tacccttagc attatcactt gctaagaaca tagcatagtc
    26041 ggcaatttct tgaacatcta ataggcgttt ttgtggtaca agtgggtata aaacttcctc
    26101 taagacattt tccaatggta tattacgagt ttttgaaagg tcattgaact gacctctgac
    26161 aagtggagta tctacatatc cagggcataa agcattaact gttataccag aatcggcagc
    26221 ttcaagagca gcaacttttg ttagtccaat aagtccatgt tttgctgagt tataagcagc
    26281 ctttccagca aatcctatta caccattgat tgaggccata tttattatac gaccaaagcc
    26341 ttgttttttc attataggaa atgctttttt agtagctata aaaggtgctg tcagcattat
    26401 ttttatcata aattcaaatt tatcagttgg gaaatcttct atcatagaaa catgttgaag
    26461 tccagcattg tttattaata tatctaatct gccatacttt tcaacagttt tgtctatagc
    26521 gtggttaatt tcttcttcct tagttacatc acactttaca ctcatgcaat cataaccttt
    26581 tttttgtaac tctgttatgg tattatttaa agcttcttga tttatatcag agaacattac
    26641 tttagcacca ttttttaaga acgattcagc tatttgttta cctattccac ttgcagctcc
    26701 tgttacgaat acaactttat ctttaaccat tttcatttcc tccaatttta ttttattttt
    26761 atattaatat tttaagcaat acaaatttat atgtaatacg tctaagagat ttttattttc
    26821 tagttttaat tattttaaac aacagatatt tttccattta atgaatctga caatattaaa
    26881 ggagcctcag tagcagaaat aacatcatct aatgtgaaag ctggatttat ttctttaagt
    26941 aaaattccat ctgatgttac ttccataact cccatttcag taactatcaa atctacagca
    27001 tttgttgcag taagtggaag agtacaatta tttaatattt ttgcagaacc ttttgaagta
    27061 tgttccattg ctacaataac ttttttagct ccagttacta ggtccatagc tccacccata
    27121 cctggaacca tcttacctgg aatcatatag tttgctatat taccatattt gtcaacctga
    27181 agtgcgccaa gaacagttat atcaacatga cctcctctga ttattccaaa agaagtagca
    27241 ctatcaaaga aacatcctcc aggaagtata gtaactggtt gaccacctgc atttacaata
    27301 gtttcatcac ttgaatttcc atcttcggct gaacctaaac ctaaaaagcc attttcagat
    27361 tgtaagataa cgtttacatt atccggaata taatttgcta ctttggttgg tagacctatt
    27421 ccaaggttta caacggctcc gtcttttaat tctttagata ctctatttgc aatatattct
    27481 tgcatttcta atttatccat tataaattac ctccttcaat gatgtaattc acaaaaatac
    27541 ctggtgtatt aacttcattt gggtcaatat caccaatttc aacgatttca tctgcttcaa
    27601 ctattgtaat tttggcagca gatgccatta aattattaaa attgttcata gagcctttat
    27661 aaactagatt acctgcttta tcgacctttg atgcaaatag aagagcaaca tctgcataaa
    27721 ttggtttttc aagaaggtat tctttgctat cgacaacaat tttttgcttt ccctcctcaa
    27781 caagagtacc aataccagtc ggtgtgagta tacctcctag accataacca gctgcacgta
    27841 tttgttcagc aagagttccc tgaggaacta actcaacatc tgtttcattg ttattcattt
    27901 gtcttccagt ttctttattt aatcctacat gagaagcaat tatcttttta aattgcttat
    27961 ttacaaccat tttgccaact cctttgtcaa taaagccagt atcattgcaa attagtgtca
    28021 aatcttttat atttttacta cataaataat caattaaatt ttctggtgaa ccattggcca
    28081 tgaatccacc aaccattatt gtatctccat cttttacatg agatagagct tcatcaatgc
    28141 taactatttt attcatattt cctcctatcg tgaaaccacc attgatattc cttgaccacc
    28201 accaatacaa agtgttgcaa gtccagtttc aactttacgt ttttgcattt cataaattaa
    28261 ggtaacaagt attctagctc cacttgctcc tattggatgt cctaatgcta ttgcaccacc
    28321 attaacattt aactttgatg aatctatttg aagttcattt ttaacagcta atgcttgggc
    28381 agcaaacgct tcatttgctt ctattaagtc tatatcattg atgctaagtc cagctttttt
    28441 cagtgctttt ctagttgcag ggattggacc agtacccatg acttcaggtt caacaccagc
    28501 tgaagcatag gattttattt tagcaagtgg tctaatacct agttcgtctg ctttttgttg
    28561 gctcattagt attaacatag ccgcaccatc attaatacct gaggcatttc cagctgttac
    28621 agtaccatct tttttgaatg caggtttaag tttagctaaa ccttcaaatg tcatacctaa
    28681 tttaggatat tcatctttat caatagtttc tatttttcct cgacgtatta aaacatctac
    28741 tggaacgatt tcttctttaa agcggttgtt ttttatagca ttctcagcct tactttgact
    28801 ttctaatgcc aatttatctt gcatttctct agtaaattca aatttagttg caatattttc
    28861 tgcagttatt cccatatgat actgattgaa agcatcaata aggccatctg ttagcatact
    28921 atctaccatg gttatgtcac ccattttact accaaagcga gcagttggaa cgatataagg
    28981 agcttggctc atattttcag taccacctgc aattaccaca tcattttcac cagatgtgat
    29041 tgattgggca gctagctgga cacttttaag ccctgaacca cataatttat ttactgtgta
    29101 gcttggaaca gaatttggta tacctgcatt tatagcaatt tgtctagcaa cattctgtcc
    29161 aagccctgtt tgaagaacat ttccaattat tacttcatct atttcagata aattaagtcc
    29221 tacacgtgat atcgcttctt taacagtgat agttccaagt tgaacagctg aagtattttt
    29281 aaatacacct ccaaaacttc ctataggtgt tctgactgct gatacgatta ctacatcttt
    29341 catatctaat agttaccttt cttgaatgat aattaaaaat tttctgaata aagaaattag
    29401 gaaacactat aataaagtac ttttttaata caagcttgtt tttaagtatt tcaattactt
    29461 ttattcctaa tgctttaggt tttcctgttt ctaattatag attacggcga aaaaagcgtt
    29521 ttgtctaagt ctaatttttt atatagtgta taagaaaaat ttataggata aaaatttata
    29581 gtagatttag aaaaatattt tgttaaaata ttaatgaaat tatgttgatt ttcctataaa
    29641 atatcattag aagaaaaaat ataatctaaa ttatactttt ggggaagggg gtttaaaatg
    29701 gatataaaac agttgaaata ttttgttgaa atagtgaaat ctggttttaa tttatcaata
    29761 gcatctaaga cacttcacat atctcaacca gcattaagtc aaattataaa aaattttgaa
    29821 gaaagtgaag atgtatattt atttgaaagg tataaaggca ggttaaatgg gttaacacca
    29881 gcaggagaaa gattttatgt aaatgcagaa catatcataa atgaatacaa aaatatgatg
    29941 gaagatttaa gagaagattc agttcaattt aaaggaaaag ttagaatagg aatacctcca
    30001 cttatacttg gaatagcatt ttcagatgta gttgcacagt tagttgcaaa taatccagat
    30061 atagaatttg atatagtaga gaagggtgca tatgacttaa atagaatgct tatcttacag
    30121 gaattagatt atgcagtatt gttacatcca cataaaattg ataaaagtgt agtaactgaa
    30181 catgtgcttc aagaagatga acttacagca tttttaaata taaatcatcc acttgctaag
    30241 aaggataaga tagattggaa cgatttgaat gagcagttac ttgcaatatt taatcctact
    30301 tttatgatac atcataagct aatgcaaaaa tttactgatg aaaatgttaa gttaaaaaga
    30361 tatataatgt ctggttcatg ggattttttg ttgctatcaa ccacaaattc tgattttata
    30421 acaattctac catcaccagt tcatgatttt tttgaaaata gcaaaattat agaaaagcct
    30481 tttaatcatc ctattacatg gaaagttata ttatgtagac ctaaaaaaga acgttatagc
    30541 catgtagacc aacatgtatt taaatttatt atagatttct ttagtaaaaa gaactcttaa
    30601 aaatgttatt aaaataacaa ataaataaat caatttttat tataataaac tattagtttt
    30661 tcatctatat gtttgagagc aataataggt tttacataac atggtagagt agtatttaaa
    30721 gttataatat acaaaatatg tattttttta aacgaaaaat aaaaacagtg tatatcttta
    30781 gataatcact gtttttattt tctatataaa atttgttaag tattactaga aaattttttg
    30841 cttattatag tcaaactcat gactgttaaa aatataagta atcctggaaa tacagctaaa
    30901 tataacttgt caaaaatatg tctttgagca tcttgaagca tattacccca tgatgcaaga
    30961 ggcaattgga ttccaagacc taaaaaacta agagcagatt cagttaagat agcattagca
    31021 atatttaacg aaccagcaac tacaatagtc tcttttaagt ttaaaactat atgtcttaat
    31081 agtatatttc tagtcttgat accagtagct ttagcagcta gacagtattc attttccttt
    31141 atttttaatg tttcgccacg tacaattctt gaaacttcca tccaacttaa gaatccaata
    31201 attagtataa tagtggaaac tttaggtgtt agataagtat ttaatacaat caaaactaag
    31261 aaacttggta tactcataag catatctact aatctcatca agaattggtc tagcttacct
    31321 ccaatatatc cactaataac acctacagca gtaccaaata ctacagaaat aagcattgat
    31381 aaaataccaa cactaagtga aatccttcca ccataaagag ctctagagaa gtaatctcta
    31441 ccaagttcgt ctgtaccaaa gatatgcttt aagctaggtt cttgaagttt agaagtagta
    31501 tcaattgcat tagagtctat atttaatata aaagaagcta taattaatat gattattatg
    31561 ctaagagtaa tacatgcaaa agcaaaggat ttatcttttt ttaatttttt taagatactt
    31621 gtaaacacaa ctagaatcct cctttgctag attttatttt agggtcaatt aataagtata
    31681 gtatatcagc aactaaatta cctaaaatta aaaatagtgc tgataacata gttattgcca
    31741 taattacagt ataatctctt gaaaaaattg aatcaatcat taatcttccc atacctggcc
    31801 aagagaaaac tacttctgta acaaatgcac cagtgactaa tttttgtata ctcatgccta
    31861 ggattgtaac caatgatgtc agtgaatttt tcaagacatg tttaaatagt atgacttttt
    31921 ctgataatcc ttttgctctt gctgtaataa catattgttt ttttaattgt tcatttacac
    31981 tagcttctac ataatttgta aaaatagcag tattatatag acctaaagtt attacaggca
    32041 aaactaaatg ttttactaag tctccaatac tatcatttcc aatagtatgc atacctcctg
    32101 atgggaaaat gttaagttta actgaaaaaa ttgaaatgag tatcatacct atccaaaaag
    32161 aaggtataga aacacctata taattaaaaa cagatgatac tttactagtt attgaatttt
    32221 tatttacagc taaaaatatt ccaagaggta tagctaccaa tattgaaaat atcaaagaag
    32281 tacccataag aataaatgta tttcccattt tttccataat ttgttctgta acgggcatat
    32341 ggtttatata agaaatacct aagtttccac ttaaagtgtt tttcaaccag tttaaatatc
    32401 ttatatatac tggtttatca agccccatat taacccttat attttcaata tcctgtgaag
    32461 acattaaagg atttatatat gcatctgctg ggtcaccagg agctaattct aaaagtccaa
    32521 atgataatat agatattaag attaacatag gtattaaaac ttttactcta ttcaatatta
    32581 attttaacat aagtaaattc tcctaattaa aagagatgtc tcgttttaaa ataataaaac
    32641 aatattattt ttagacatct ccttttctaa ttaataatat aaaattttac atcaattatt
    32701 ctacatacag tttagaccaa tcttcaaata atattgcagg agatggttta gcatctttta
    32761 ttccttttag atttttttga gctgccatta aattttgttc ataatctata gtgtaaatag
    32821 gcgcatcctt agatatatcc tgttgtattt gcttatatat ttcttcacgt ttttccttgt
    32881 ttaactcagt aaatcctttt tcccataaag catctatttc agcattagaa tatttagttt
    32941 ggttgcaata ttgaccagtt tcaaacatac ctctatatgg gtttggttct aatccccaag
    33001 cataaccatt tacatacata tcacattcag tgctattact aaatagtata ttgaagaatg
    33061 ccttactttc ataaggaact atttcagctt ctataccaat ttttttcaac tcttgttgag
    33121 ctactaaggc atagttttta tgcccaaatc tacctgtgtt ataacctatt tttaatttat
    33181 caattttaac accactttta tccaataagt ctttagcctt atttgtatct tggtcatatc
    33241 cttcaacacc ttcttctgta tagaagtctg cttctggaac taatatagat ttagcaggta
    33301 cagaaccttc ttttccatat gctgattcta tcatttcatt tctatttaag gcatatgata
    33361 aggcttgtct tacttctttg ttagccatgt ttgatatatt ttggttaaat acaatgtagt
    33421 ttaatctttc ttcactataa gtataagttt gtaagtttga gtttgatttt gccttttcat
    33481 atccttcagc agatgtcttc ataagtgaaa tttcgccatt atttaaagct gcttcttgag
    33541 atgcttcatt aggaattatt tttagcgcta tagaatctgc cttaggttct ccaccaaaat
    33601 aatctgcatt cttttcaaat actatgcttt cacctttttt ccattcctta aacttgaatg
    33661 caccagaacc aactggatta ttattttttt ctgacttagc tatatttgat tctccttcaa
    33721 acacatgttt tggtattgga gaaattttag atataccata taagaaagat tcacttgcag
    33781 ttggtaaagt aatcttaact gttaaatcat caattttttc tactttaact ggtttctcac
    33841 ccaccaataa gtattgtctt gatggtgaat tttgtttttc gtctaaaact gtattaaatg
    33901 taaataagac atcttcagca gttattggct ttccatcatg ccattttaaa ttggatttta
    33961 attttatagt taattcctta ctatctttaa aatctacttt ttctgctaaa taatttacta
    34021 aatttccttt ttcataagta taaagaggag cataaactat atttgatgca agagagtctt
    34081 ctttaacgtt tgcaaaagct ccattgatta tatctgggtc acttgccata ggtattacaa
    34141 cagttccacc agatttgctt ccactagact tgtctttatc attggaagca caggctgtaa
    34201 atgtaagcat taatgatgaa actaagatta atgatgccaa ttttttaaat ttcatattct
    34261 tataaaacct ccataaaata atatttaaca catatttttt attgtataat agtaatcatt
    34321 attaaatcaa tatatataga aattaactat tatattatta taattaatag aaaaaaataa
    34381 taaaatgtaa gaaaatgttg taatttaaat ttttataaaa tacaatcaaa aggtgtatgt
    34441 tatcttaagt aattttgctg agaggagaaa ataatgagta aagcactaat tgaggttaaa
    34501 gatttaaaag tttattttca tacagataaa gggattgtaa agagtgtaaa tgaagtaagt
    34561 tttaatataa atgaaggtga aactattgga atagttggag aatcaggatg tggtaagtct
    34621 gtaacagcca tgtctttgat gaagttactt ccaacatcaa aaatagaagg tggagaaata
    34681 atctttcgag gcaaagacat tttaaagatg aatgaagatg aacttatggg aataagaggg
    34741 aatgagatat caatgatttt tcaagaacca atgacatctt taaacccagc gtttactgtt
    34801 ggaagtcaaa tcattgaagg tattatgata catcaagatt tatcaaagga agaagctaag
    34861 aaaaaggtaa tcgatatgat aaaactggta gaaataccaa gagctgaaga aatatataat
    34921 tcatatccac atgaattatc aggtggtatg agacaacgaa taatgatagc tatggcttta
    34981 tcatgtaatc caaaattact tatagctgat gaaccaacaa cagctttaga tgttactatt
    35041 caagctcaga ttttagatat aatgaaaaat ataaaagaaa aattaaacac atctataatg
    35101 atgattacac atgatttggg agtagttgca gaaatgtgtg acaaagtatt agtgatgtat
    35161 gctggcaaaa ttatagaagt ggcagaggtt gttgaattat ttaaaaatcc aaaacatcct
    35221 tatactattg gacttctaaa atcaaagcct gctcttggaa aaaacaaaga taaaagattg
    35281 tattcgattc caggacaagt accaaatcca attggaatgc cagattcatg ttattttagt
    35341 gatagatgtg aaaaagtatg tgataaatgt agaactcaga tacctccttt aatagaattg
    35401 aatagtggtc atagtattgc atgttggtta tataaaaagg aggagatata attgaaaaaa
    35461 gaagagagtt tattaaaagt agaaggtctt aaaaagtact ttgaagttaa atctggatta
    35521 tttgataaga aaattaaatc tgtaaaggca gtagatggaa tttcttttga tttaaaaaaa
    35581 ggagaaactt tggctatagt tggagaatcg ggatgtggaa aatcaactgc aggaagaacc
    35641 attcttagat taattgaaaa aactgaaggt aaagttgaat ttaatggtgt agatatatat
    35701 aagttagaga aggaagaact tagaaagtta agacccaaaa tgcaaatgat atttcaagac
    35761 ccatatagtt cattaaatcc aagattaaat gtggaacaaa taatatccga ggcagttata
    35821 gaacataatt tagtgccaaa gaatgaaata aaagataata tattaaatgt tgtagaaagt
    35881 tgtggtcttt ctaagtacca tttaaataga aaaccaggtg agttttctgg aggtcaaaga
    35941 cagagaatag gtatagcaag agcattagca ttaaatccag aatttatagt ttgtgatgaa
    36001 cctgtttctg cactagatgt ttctattcaa tctcaaatta taaatttact tatggattta
    36061 caggataaat ataaactttc atatttattt atatctcatg atttgagtgt agtaaatcat
    36121 attgcacata gagtttgtgt tatgtatcta ggttctataa tagaaattgc aactaaagga
    36181 gaactttact tacattctca acatccatat acaaaagcac ttatgagcgc agtaccaata
    36241 caagacccta caattaagaa aaatagaatt atattaaaag gagacatacc atctccaaca
    36301 aatccaccaa gtggatgtaa gtttcataca agatgccctt attgtaagga aatatgcaaa
    36361 aaagagattc cagttttaaa agaaatatca agaaatcatt ttgttgcatg tcatctagta
    36421 tagatatttc aaaaattaaa tttgatgtat ataataagaa taatagaata aactgaaaat
    36481 ttttttgatt aagatgggat ttcatgctgt taatattaag ttagttgata tataagttta
    36541 atctataata ttattattga aaagagaggt agttatgtca attttagtaa cattgttggg
    36601 attattggtt tgtacaacga tttcaactgt atttagcaaa aagtggagta atattcctct
    36661 tgcaatatat caaattgtac tagggattat attgtctatt ttgccattta aattctcatt
    36721 ttcatttaat ccagaaatat ttgtaatatg tatcatagct ccattactat tcagtgaagg
    36781 acaaaatgta tcgagaaaag agctattaga gcttagaaaa ccaattttgc ttcttgcatt
    36841 tggtttagtt ttaataaccg tgtttgcagg tggaatcttt atacattttc ttattcctgg
    36901 gatgccatta tctgtttcat ttgctttggc agcagtaata tctccaactg atttagtagc
    36961 agtaaaatca attacacaag gattaaattt tcctaaaaat ataatgagta tacttgaagg
    37021 tgaatcttta ttaaatgatg ctgctggagt agtagcattt aaggttgcag tacttgctac
    37081 agttacagga gttttttcaa tagaagaggc agggattcaa tttatgatta cagcttttgg
    37141 aggaataata gtaggaagta ttttaggata cataattata aaaataagac ttagtttaca
    37201 caagtggaat ttggaagaaa ttccaatggt aatagttata caaataatga ctccactttt
    37261 tgtatatttt gtagcagaag aaataggagt atctggaatc ctagctgttg taatggcagg
    37321 gatagctcat ggaattgaaa aagagcattt acaaaataca actactaaat taaggataat
    37381 atcagacaat acttggtatg ttttggagta tgtattgaat ggatttgtct ttacactgct
    37441 tggttttttg ttaccaagta tatatacagg acttagtagt aaaaatgaaa atatggcatt
    37501 ggaattgact tttatttcta ctttaattgt acttatttta tttgttataa gatttatatg
    37561 ggtatattta tggcataatt cttttataaa acctaaaaag aatcctttaa ataatttttt
    37621 tgtaggtttt ttaggtttta aggatgaaga agttataaaa gagagtattt ctaaatgtaa
    37681 atactcacta atagttgcta cttgtggtgt tcatggtaca tttacactag caactgcctt
    37741 atctatacct ttttatttgg ctgataaaga tgtatttcca atgagagata ctgttttatt
    37801 tatatcatca gaagttattc ttataagttt agtattggca acaattttac tgccaagatt
    37861 attaaaaaat aacgtacaag agtcagaacc tttattatct gataaagagg catataaact
    37921 aattttgaaa gaagccattt taaaacttag taatgaaaaa gcacaagaag tacaaccagt
    37981 tatacatgat ttaaatgaac agttggtaga ctcagaaaaa ggaatactaa atactccaga
    38041 taataaactt ataagtatga tgattgcaga agcagaccaa cagggattat tagctgtttt
    38101 gaaactatta gaagatggta aaatttctga tagagccttt aaattgtata gattttatat
    38161 tacaaaatca agaaaatctg ttcaaaaatc tatatttaaa attgtaaaat taaaaataag
    38221 catgtggatt ataaatagaa aagtaaagaa agaagtaaaa gaaaaaatta caaaaatagt
    38281 atctgagaat aaagaaataa tcaaagagtt tcaccatgca tatgcacttt ctactaaaac
    38341 tgctatatca tttataaata aaaatactga tgaagataac agacatgagg ccttaatagc
    38401 aatcagattc tataatcgtt atttgaattg gattactaga aagattcaaa atgatgataa
    38461 gtttgaggca agagtagaat actacagagt aatggcgata caaagtcaaa gagacagtgt
    38521 tcaacaatta gttgaaacta agcaaatatc aagagaagtg gctaaagagt tattggaaaa
    38581 tattctctat gatgaaatga tgatgataga atcataaata taatggaata aaatttgatt
    38641 tttgatgtta aaattaatac taaaaaatag gaaatagttt tcaataattt acttgacata
    38701 tatatttatt tataatagaa taaaaccata aattgaatac aatatataag cattaacaag
    38761 ctggattgtt actggtaagc aggcaatacc taggttaagg tatacaggtg aattgtatct
    38821 taatttaggt atttttttat gaataaggga aattgtattt tgggagagat attgattatg
    38881 attattcaac aaatttataa taataatgtt gtattagttt tagatgaaaa tataaaaaaa
    38941 gaattaatat taacaggatg tggaattggg tttcaaaaaa agaaaggtca agaaatagat
    39001 aaaagtaaaa ttgaaagaac ttttgtaata caagatgaaa gctttttaga taaaattagt
    39061 aaactagcaa gccaggttga tgagaaattt tttgaggtta gtactgaaat aattgcttat
    39121 gcagaggaga acttgaatac taagctttat gaatatattt atgtagcact tactgaccat
    39181 attgcatttg caattaaaag atatcatgaa aacataacta taaagaatga tttactacat
    39241 gagataaaaa gaatacataa aaaagaatat gagattggga aatgggctgt agattatata
    39301 aataaagaat ttgatgtgaa atttccagta gatgaagctg gttttatagc aatgcatata
    39361 gtaaattcaa actataaggg aagttcaaag gaatcactat taattactaa aattgtaaaa
    39421 gacatactaa atattataag atattattat agagttgaat ttaaagaaga tgatataaat
    39481 tatgataggc ttctgactca tttaaaattc tttgcaaaac gattagtaaa aaaagaaaaa
    39541 atcaatgata caaataatga aattatagat ataattaaag taaagtatga aaaggattat
    39601 gattgtgcat ataaaataaa aactcatgta gaaaagaatt atgattacta tgtaagtcaa
    39661 gatgaactac tttatttaac attacatatc aaaagagtta tatctgtact gaatttataa
    39721 taaagagtag tttaatacag aatgtatag
//
LOCUS       DAEPXW010000032        39467 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.033, whole genome shotgun sequence.
ACCESSION   DAEPXW010000032 DAEPXW010000000
VERSION     DAEPXW010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39467
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.033"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            445..3993
                     /locus_tag="KRM55_001593"
     CDS             445..3993
                     /locus_tag="KRM55_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1593842.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADIALY
                     SAKGKGKNCYTLYDKKFDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            4178..6112
                     /locus_tag="KRM55_001594"
     CDS             4178..6112
                     /locus_tag="KRM55_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBH1593843.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            6218..7213
                     /locus_tag="KRM55_001595"
     CDS             6218..7213
                     /locus_tag="KRM55_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1593844.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7185..7970
                     /locus_tag="KRM55_001596"
     CDS             7185..7970
                     /locus_tag="KRM55_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1593845.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7958..8656
                     /locus_tag="KRM55_001597"
     CDS             7958..8656
                     /locus_tag="KRM55_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593846.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8779..9252
                     /gene="ybaK"
                     /locus_tag="KRM55_001598"
     CDS             8779..9252
                     /gene="ybaK"
                     /locus_tag="KRM55_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBH1593847.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9449..10288
                     /locus_tag="KRM55_001599"
     CDS             9449..10288
                     /locus_tag="KRM55_001599"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBH1593848.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10301..10849
                     /locus_tag="KRM55_001600"
     CDS             10301..10849
                     /locus_tag="KRM55_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBH1593849.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10915..12096
                     /locus_tag="KRM55_001601"
     CDS             10915..12096
                     /locus_tag="KRM55_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBH1593850.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12391..12777
                     /locus_tag="KRM55_001602"
     CDS             12391..12777
                     /locus_tag="KRM55_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1593851.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYNMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12927..13190
                     /locus_tag="KRM55_001603"
     CDS             12927..13190
                     /locus_tag="KRM55_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1593852.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13319..14161)
                     /locus_tag="KRM55_001604"
     CDS             complement(13319..14161)
                     /locus_tag="KRM55_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1593853.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14456..15190
                     /locus_tag="KRM55_001605"
     CDS             14456..15190
                     /locus_tag="KRM55_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1593854.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            15200..16333
                     /gene="nagA"
                     /locus_tag="KRM55_001606"
     CDS             15200..16333
                     /gene="nagA"
                     /locus_tag="KRM55_001606"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH1593855.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAKVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            16432..17181
                     /gene="nagB"
                     /locus_tag="KRM55_001607"
     CDS             16432..17181
                     /gene="nagB"
                     /locus_tag="KRM55_001607"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBH1593856.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17356..17628
                     /locus_tag="KRM55_001608"
     CDS             17356..17628
                     /locus_tag="KRM55_001608"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593857.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18288..18992
                     /locus_tag="KRM55_001609"
     CDS             18288..18992
                     /locus_tag="KRM55_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1593858.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            18994..20481
                     /locus_tag="KRM55_001610"
     CDS             18994..20481
                     /locus_tag="KRM55_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1593859.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIEFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20686..22299
                     /locus_tag="KRM55_001611"
     CDS             20686..22299
                     /locus_tag="KRM55_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1593860.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22661..23491)
                     /locus_tag="KRM55_001612"
     CDS             complement(22661..23491)
                     /locus_tag="KRM55_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1593861.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKTYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23564..25291
                     /locus_tag="KRM55_001613"
     CDS             23564..25291
                     /locus_tag="KRM55_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593862.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25328..27190
                     /locus_tag="KRM55_001614"
     CDS             25328..27190
                     /locus_tag="KRM55_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593863.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27523..28212
                     /locus_tag="KRM55_001615"
     CDS             27523..28212
                     /locus_tag="KRM55_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBH1593864.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTISVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28317..29003
                     /locus_tag="KRM55_001616"
     CDS             28317..29003
                     /locus_tag="KRM55_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBH1593865.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            29020..30927
                     /locus_tag="KRM55_001617"
     CDS             29020..30927
                     /locus_tag="KRM55_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBH1593866.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSADLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            31380..32069
                     /locus_tag="KRM55_001618"
     CDS             31380..32069
                     /locus_tag="KRM55_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593867.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            32505..33044
                     /locus_tag="KRM55_001619"
     CDS             32505..33044
                     /locus_tag="KRM55_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593868.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            33063..34106
                     /locus_tag="KRM55_001620"
     CDS             33063..34106
                     /locus_tag="KRM55_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593869.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            34108..34944
                     /locus_tag="KRM55_001621"
     CDS             34108..34944
                     /locus_tag="KRM55_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593870.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            35049..35723
                     /locus_tag="KRM55_001622"
     CDS             35049..35723
                     /locus_tag="KRM55_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593871.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            35723..36775
                     /locus_tag="KRM55_001623"
     CDS             35723..36775
                     /locus_tag="KRM55_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1593872.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            37005..37853
                     /locus_tag="KRM55_001624"
     CDS             37005..37853
                     /locus_tag="KRM55_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1593873.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            37843..>39467
                     /locus_tag="KRM55_001625"
     CDS             37843..>39467
                     /locus_tag="KRM55_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1593874.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNLYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYIGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLNKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     LTKSDTRFKSISNISKILIFIVSISVLIFVIIF"
BASE COUNT        15621 a         4043 c         6883 g        12920 t
ORIGIN      
        1 attatctggt aacttaagtt ttgagtatta atctaaagta tatgttttta tatggtttaa
       61 attttatgta tacaaaatta atttgctaac tgaatcatat aaaaaaaaac aaaatatttt
      121 ttagagggaa tgattagata gaattttttt gttatgaaat taattgaaga gtaattaatt
      181 agaaaaggaa tgaataataa tgaatatatt acattattac tttttgataa atcaaaaata
      241 aagttataat ttttaatatt aattaagaat gatgaaatat gaataaagat tttacaaata
      301 aatcttaagc tatcttattt aattctaata caggaagaag gtaaatgtat attgaaaaaa
      361 tcatagaaat agaagtaaac aatttaaata aatacaaagg tttgcaaaag aagtaatata
      421 attatataca atgaggatgt gagtatgatg aacagactaa agccaagaat tttaggtatt
      481 agtatcttgt ttattattat aattatttta acatgtggag ctgttttcaa gtttaaattt
      541 aaattagata ataaattaaa agaaaccaca catacatatt tgtctgagtt tacagaacac
      601 aatataatta atctcaagac aagacttagt ggtcaatttg acatgcttga atctattgct
      661 aacttcatag gaaacttgaa taatataaat gatgaaatgg tgattgattt aatggattct
      721 gatgtaaagc gaagttcttt aattagaatg actatctcta cattagatgg ggaatgttat
      781 tctaatgatg gaattaccca taatgttcaa gatagagatt attttaaaaa agctaaaaat
      841 ggagaaaaga atatatcaga gcctttaaaa tctattgtta ataataaaga aataatagtt
      901 ttatctaccc cagtttataa aagtgggaaa atagttggtg ttttaagtgg aatttatgat
      961 tcaaaaaagt taaatgagtt attaggatta tctgcatttg atgaaaaagc agatgttttt
     1021 gttgcaaaga aaaatggaga tatagttgct caaaaaacaa ataaaaatag aaagacgcta
     1081 tcatgtatat ttcagctttt tgacaaagat aattgtgatg aagatgattg tctaaaaact
     1141 ataaaagaaa atatgaaaaa tgataagtct ggatatttta attataactt agataatgaa
     1201 aaatttatgt taaactatca gccacttgga gttaatgatt ggtatgtttt ttctgttgtg
     1261 ccaaataaaa tagtatctat tcagtcagag aatatatctt atgatgtata tatttttgca
     1321 ttagaaatac tactagttat attgattttt ataatatata tagcatgtat tataaataat
     1381 aacaccaaaa ttattataaa tgaaaaagaa aaatttaaag tactcactga taatatatta
     1441 ggaggggtta aaacctgttt aaaagatgaa tatatgacta tgacatatgt aagtcagggg
     1501 tttttagagc ttacaggtta ctcttgtgaa gatttaaata aaatatttaa aaatagattt
     1561 aaagacatga tttataaaga tgatttagac aagtttaatt gtattattct aaatcaatta
     1621 gaaaaacaag ataaaattga agttgaatat agaattgtaa gaaaagatgg aagtataatt
     1681 tggattttgg agagaagtaa gtctataaat gataataaag gaagtgagtg tattcaggga
     1741 gttttaactg atataacaga acttaagaaa atacaagaag aattagattc aaaaagattt
     1801 gaaatacagg ctatcaatga tagtattgtt ggtggaatag tgataactga gataaatgat
     1861 gattttgata gtatatattt aaatgaaggt tatttaaata tgattggata tacacgcaaa
     1921 caactggaag atgagctaaa taataaatta atcaaactta tttttaaaga tgatagaaca
     1981 gaattaatta atagtataaa caaacaactc aaattaagtg atacatttgc atctgaacaa
     2041 agagttgaaa aaagggatgg cactattata tggattttat taaaaggaag aaagatgatt
     2101 tatgataatg gaaaatctgt actttgttgt gttattgtag atattacttc tgctaaatta
     2161 ttagagcaag aacttaaaaa gagtgaagaa cgtcatgaaa tcattctaaa gcagacgcaa
     2221 aatattataa tagaatggga tatagaaaaa gataaaatga atatatcacc taattggtat
     2281 aataagttta aatatgaccc tataactgaa aacgcaacaa aaaatataat taaatcagta
     2341 gatatatatc atgatgatat ggataagttt atttcattaa ttaaacttac ttcacaaggt
     2401 agtgagtatg aagagtgtga aattagactt agaactagag atactattta cgcttggttt
     2461 agtataaagg caacaacttt atttgataat aatggtaaac cttataaagt agtaggaagt
     2521 ttgactgata ttgatgaatc aaaacgagaa gctgaaaagt tgaaagaaag ggcagaaaaa
     2581 gaccctctta cagatctgta taataaaaaa gcatcacaat cacttataga ggagtacata
     2641 acattggata aaaaaagaaa aggtgcttta atgattattg atattgatga ctttaaagga
     2701 ataaatgata atttaggaca tttatatggg gatgctgtat taagtgaaat tgcaaatgac
     2761 ctaataaatc tatttagagc aaccgatata gtaggcagaa ttggtggaga tgagtttatt
     2821 gtatttataa aagatatttc tgaaacaaga gatattataa ataaagcaga agaattggta
     2881 aaaacatttg aaaggtcttt tttaggtaaa ggacgaaatt ataaaatatc attaagtgta
     2941 ggaattgcta agtttccaca agatggtatg gactatatga cactatttag aaatgcggat
     3001 atagctcttt actcagccaa agggaagggc aagaattgtt atacattgta tgataaaaaa
     3061 tttgataaag tccaatatat aactaataca agaaatgcag gagatagtga taatgtagag
     3121 atgtctttta aagaacatat cacaaattat atatttgata tactatatga atcaagtgat
     3181 atagaagtgg cagtaaattt aattctaagt attgtaggta aacactttaa tgtgagtcgc
     3241 atgtatatat ttgaaaattc agatgataat cgagtatgta aaaatacatt tgaatggtgt
     3301 aacgaaggtg taacctcgga aattaataat cttaaaaata tttgttacaa ggatttaggc
     3361 aactatcttt taaattttaa tgcagatggg ttattttatt gtaatgatat tgaaaattta
     3421 ggtagtgatg tgaaaaaagt acttaagcca caaggcatac gttcaatatt acaatgtaaa
     3481 attttagagg gtaatgaatt tagagggttc ataggatttg atgaatgttc atataatcgt
     3541 atgtggacta atgatgaagt gaacactttg acatttatat ctaaaacgct cagtatgttt
     3601 ttattaaaaa tgcgtattca gagtaagcta gaagagtctt taacaattca aaaatctgtg
     3661 atggataata tggatatatg ggcatatgtt gttgacagga atacctatga attactattt
     3721 atcaataaaa aaatgcttga gtcagcacca aacactcatg taggtgattt atgttataaa
     3781 gcgatatgga ataatcaaga taaaccttgt aaaaaatgcc ctatgatata tttaaaagat
     3841 ggtgatgata cttataaatc attcatgcat aataaaaagt ttgaggtaca ggcaaatata
     3901 actacaacta ctttgaaatg gtttgatggt aaagatgcat gtttaatatt tggaagtgaa
     3961 ataactagta ttgaagctga agaaaatact taaaatactg tgttatatat atacttaaaa
     4021 tcgcaatttg aatttattag acttaaaatg tctatataaa tcatttaagt tgtggtttta
     4081 agtatttttt atgatataat taagcgttaa gaacaaaatt aaaagatact tttgtataaa
     4141 aaaatatttg ttaaatatat attgagcagg tgataatatg gaaaataagt ttttaccaat
     4201 aagcaaacaa gatatgatag atagaggatg ggaagaatta gattttgttc tagttacagg
     4261 agatgcttat gtggaccatc atagttttgg aacagcaata atatctagag ttttagaaag
     4321 tgctgggtat aaagttggaa taatagctca accagactgg agaactacag atgattttat
     4381 gaagctagga aaacctagac ttgcatttct agttaatgca ggaaatatgg attcaatggt
     4441 caatcattat tctgtaagta aaaagcatag agaaaaggat atgtattctc caggtgggaa
     4501 aatgggttat agaccagata gagctactat agtatattgc aataaaataa gagaagcata
     4561 cagtgatgtt gcaatagtaa taggtggaat tgaagcgagc ttaagaagat ttgcacacta
     4621 tgattattgg agtgataagg ttagaaagtc tatgttaata gatagtggag cagatttatt
     4681 agtttatggt atgagtgaaa agcagattgt agaagtagcc aatgcactta atgatggata
     4741 tgacccaaaa tacattagac atattgatgg gacatgctat atttcagata cattggaaga
     4801 aatatatgat aaatatatat taattccatc atataaagaa atttgtgaag ataaaatgaa
     4861 gtatgtagaa gcttttaaaa ttcaatatga tgagcaagac ccatttagag gtaatataat
     4921 tgttcaacct catggaagta agtatctggt tcaaaataag ccagaaaaac cacttagtag
     4981 agaagaacta gatgaagtat atggattacc atatcagaag acataccatc ctgtgtatga
     5041 aaaatttgga ggaataccag ctatagaaga agtaaaattt agtatagtaa gttcaagagg
     5101 ctgttttggt agttgttcat tttgtgcaat aacatttcat caaggtagag cagtgcaaag
     5161 tagaagtgaa aaatcaatta ttgatgaagc aataggaata acaaatttag atgattttaa
     5221 agggtatata catgatgttg gaggtccaac agctaatttt agaagaccag catgtaaaaa
     5281 acaaattact aaaggtgctt gtaaaaatag acaatgctta tctccatcac catgtaaaaa
     5341 tttagatgca gaccacagtg aatacttaca tttacttaga gctgtaagaa aattacctaa
     5401 aataaaaaag gtgtttgtgc gttctggaat tagatacgat tatgtaatgg cagataagaa
     5461 caataaattt cttagagagt tgatagagca tcatgtaagt ggtcagttaa aggtagcccc
     5521 agaacatata tcagaagaag ttttaaagta tatgcaaaaa ccagcaggaa aaacttatga
     5581 taaatttaga cagaagtttt ttgctataaa tgaagaatta ggtaaaaagc aatatttgat
     5641 accctattta atgtctagtc accctggttc taccttaaat agcgctatag agttagcaga
     5701 gtatttaaga gatactcact accaaccaga gcaggttcag gatttttatc caactccagg
     5761 gactctatct acaaccatgt tttatacagg tattgacccg cttacaatga agccagttta
     5821 tgttcctaaa tcaaaacgtg acaaggcgat gcaaagggct ttattacaat atagagcacc
     5881 tagaaattat gatttggtat actctgcgtt agttgaagca ggaagagaag acttaattgg
     5941 ttttggacat agatgtctta taaagccaaa aaatgaaaag ccttatttta atagaaataa
     6001 ttctaaaaaa aatgtatcta aaggaacaaa taaaaacaaa aaaactaata caaataacag
     6061 aagtaataaa aatcaacaaa aaagttcaac taaaaaaaag aaaaaacatt aaagtataaa
     6121 taaaaatact taaaaaagaa ggattattcg ataaattaac agaaattagt ataaataaat
     6181 ataattattt taatgacgtt acctttggga ggaagagatg aaaaagtata tttctataat
     6241 attattagtg gtgttgacta tggttgtttt ggtaggatgt tcaccaggaa aagataaccc
     6301 taaaaataag gagctatcag ttgtcaaaca agtaaaagta gctgttccag atggactacc
     6361 agcagtggca atagctaaac ttgcaaatga aaatccagag attaaagaag gatatgaaac
     6421 agtgtatagc attgaaaaga cacctgaagc gatttccact agagtgatga aaaaagatgc
     6481 agatatagct atagttcctt caaacatggc tgcaatagcg tataataaaa cttcatcata
     6541 taatattgtt ggaactgtag gaatgggttc actttatttg gtgtcaacag aaaatataaa
     6601 agattattct gatttagttg gtaaagaagt tggatgtact ggaaaaggac ttactccaga
     6661 cataactata aaaagtcttt tgttacaaaa ggatataaat tattcagata taaaatttaa
     6721 ttatgtaaat tcagcaagtg aactggtacc attattggct actggtaaag ttaaaacagg
     6781 tattgttcca gaacctgcac ttagtgcttt gatgtctaaa aatccagaca taaaaattat
     6841 aaaaagttta aatgactcat ggaaggaagt aagtggttca aaagatggtt atcctcaatc
     6901 tactttaatt gtaaagtctg aatttttaag agataataaa gattttgttg attcttttgt
     6961 aggtcaatta tcaaatagta tagattgggc aaacaaaaat cctgaagaat taggtgcata
     7021 ttctgaaaaa ataaaaatat ctactgaatc aaagataata ggaaaatctc ttgaaagagc
     7081 taatttaaaa tatattccag ttaaggacat gattaaagat tataaaaatt actatgagaa
     7141 attagctaat tttgatgata agacattagg aggcaaagta ccagatgaag caatatactt
     7201 tgttgagaaa taaaaaaaat aaagaacaat ttatagataa aatggaggta acactttctt
     7261 gtgttatcct cttattttta tggcaaatta ttgctttaaa aattgataat gatatttttt
     7321 taccaacagt aggtcaagta tttaatagta taaaagagat tatgctaaat tctagtttct
     7381 atatagatat actttactct atggggagat gtttttttag ttttttactg gctatgattt
     7441 ttgctattat actttcaata gtgtcttatt taaatagatt ttttagaaac ttattaaagc
     7501 caatcaatgc tttgacacgt tcaataccaa ctatgatatt ggtagtactt gcacttattt
     7561 ggtttgaaaa ggatagtacc ccttttatag ttggatttac tatagttttt cctatattgt
     7621 atgataacgt tttgggcgct atattgaata tagacaagaa cttattagaa atggctaatg
     7681 tgtataaaat aaggtttata gataaggtgt taaaaattta tttaccagcc ataaaatttc
     7741 aaattatatc tatactagta tcaacattct ctttaagttt gaaagttgct atagcaggag
     7801 aggtatatag tcaacctaca tatggtattg gaactatgat acagactgaa aaaattaact
     7861 ttaacacatc tggaatattt gcatggataa ttattgttct tttaatatct gctattttac
     7921 aaatagctca aaagttttta gcaaggagag cttttttatg gaaaagataa agttgagtat
     7981 tgaaaatata aataaaagat atgatagtcg tattatattt agagatttta atattgattt
     8041 ttatgtaaat gaggtaaatt gtatccttgg aaaatctggt tgtggaaaaa ctacactctt
     8101 gaacataata agtgggatta ttaaaaatga caccaacaat ctaaatatca aagaaaattt
     8161 aaatagagta ggaaataagc ttgaagctag ttacatattt caagatgata gacttataga
     8221 ctggttaaca gtagaagaaa atataaagat agttgtaaat aaatactata ataaaactca
     8281 attaaataaa atttgtgatg aatacttgga attggttgga attagtgatt ataaaaaatt
     8341 ctatcctcag atgcttagtg gaggtattag acaaagagta aatattgcta gagcttttat
     8401 atatccatca aaaaatatta taatggatga accttttaaa tctattgatg caaagaatac
     8461 acagcttata atggataatt tcagaaatat attaagaaaa gaaaaaagaa ctgtgttatt
     8521 tgtaactcat aatattgagg aagcattgtt tttagcagat aggatattta ttttaggaga
     8581 ctctccaatt agaataaaaa aaatattaaa aaattctaag gaattggaaa aaaatgaagt
     8641 tttgaagttg atatagagtt ataataatac tgtcgtttta aaatatattt ggttaaaatc
     8701 tataagacta tattaaaata gtacagaata ttcaaaactg tgtataatgt tcgtatttta
     8761 taaaaaggaa gtgaatgtat ggttaagact aatgctatga gaatattaga ttcaaataag
     8821 attgattata aagtaatgtc ttatgaagtg aaaagtgaac atgtggatgg tgttgaggtg
     8881 gcacatgata taggaagaga tgtaaatgaa gtgtataaga cattagtaac tcaaggagtt
     8941 agtaagaata tatatgtata tgtaatacca gtacatgaaa acttagactt aaaaaaggct
     9001 gcaaaagtag ctaaagagaa aagtgtagag atgattcatg taaaagatat aaataagctt
     9061 acaggttata ttagaggcgg atgttctcct ataggtatga aaaagcttta taaaactttt
     9121 gtaaatgaaa gtgcaaagaa tttagataca attattgtga gtgcaggaaa aataggatat
     9181 caaatagaac tatctccatt tgatttacaa agacttataa aagtagaatt tgtagatgta
     9241 ataaaaaaat aagaattaca tataaaatat agagcttata ttcttaataa taggtgttgt
     9301 agtattaata aaatgaataa taattttaaa ataaatattc agttacttat gtgtaattgg
     9361 tataaaaata ttgagaaatt ttaaaaacaa tggtaaagtg taagtataat cacgaatatt
     9421 ttttataaag taatggaggg atgttcgctt gagaaaaata aaatctgaac aaatcgtcga
     9481 gcaggtaaaa aaactttgta tagaagcgag cctatattta ggagaagatg ttttaagctg
     9541 tataaaagaa aaagcgaaaa gtgaaaagag tgaagttgga aaaaatatat tgaatatatt
     9601 agttgaaaat gctgaaatag ctaaagaaaa aaatatacca atatgccaag atactggtat
     9661 ggctgtattt tttgttgaaa taggacaaga agttttaatt gaaggagaca cacttactga
     9721 tgctataaat gagggagtaa gacaagggta tgaagaaggc tacttaagaa aatctgttgt
     9781 aagtccaatt aacagagtaa atacaaaaga taatacacct gctgttattc attatgatat
     9841 ggtaaaaggt gataaaatta aaatagaatt tgcagctaag ggatttggaa gcgaaaatat
     9901 gagtaagatg aaaatgttaa agccatcaga tggattggaa ggaattaaaa aattcataat
     9961 agatacagtt tcagaagctg gacctaaccc atgccctcct atggtaattg gagttggtat
    10021 aggtgggact gtggacaaat gtgctcaaat agctaaaaag gcacttttta gagaactagg
    10081 tgaatttaat aaggacgaaa atatagcaaa acttgaaagt gaactattaa cagctattaa
    10141 taaacttggt ataggacctc aaggcttagg tggtactaca acagctttgg gattaaacat
    10201 agagactttt cctacacaca tagcaggttt acctgttgtt gtaaatataa actgccatgc
    10261 atcaagacat aagaaggtag taatttagga ggaaaataaa atgataaaaa taactacacc
    10321 tgtaaatgaa attgatatag caaaattaaa ttgtggagat acaattagtt tgagtggtat
    10381 actttataca gcaagagatg ctgctcataa aagattgata gattgtataa ataaaggtga
    10441 agaattacca tttgacgtat atggtcaagg aatatattat gtaggaccta ctcctacaaa
    10501 gccaggagaa gttataggtg ctgcaggtcc aacgacgagt tatagaatgg atgatttgac
    10561 tatacctctt ttagaaagag gtcttagatt gatgataggc aagggaaaaa gaagtgatga
    10621 agttatagaa ggtatgcaaa aatacggagc agtttatctt gctgcaatag gaggagctgg
    10681 agcatatatt tcaaattcaa taaaatcatg tgaaattatt gcatatgaag atttaggagc
    10741 tgaagctata agaaagattg tagtagaaga ccttaagctt acagtagcaa tagatagcta
    10801 tggaaataat atatatgagc aaggtcgagc aatttatgaa tgtaaataat gtttagaaat
    10861 aaatatgaat atcaaaatta aaaatagttg tgtatatttt aaggaggaaa attgatgtct
    10921 aaggattatg caaaattggc attagaaatg catgaaatca acaaagggaa agtaagtgta
    10981 gaaagcaagg tagaagttaa aactaaggat gatttatcaa cagcatatac accaggggtt
    11041 gctgaacctt gtttaaaaat acatgaaaat caagatgatg tttatagata cacttctaaa
    11101 gggaatctag tagcagtagt tagtgatgga agtgctgtac ttggattagg taacattggt
    11161 gctgaagcat ctatacctgt tatggaaggt aaagctatat tatttaaaca atttgcagat
    11221 gtagacgctt ttccaatatg tttaaagact aatgatgtag atgagatagt taaatctgta
    11281 gagttgatgg agcctgtatt tggaggtata aatttggaag acatatcttc tccaagatgt
    11341 tttgagatag aagagagatt aaaaaaatct ttaagtatac ctgtttttca tgatgaccaa
    11401 catgggacag caataatagt tgcagcagcc ataataaact caataaagtt aattgaaaat
    11461 aaaaaaatag aagatttaga aatagttata aacggagcag gagctgctgg tatagccata
    11521 gcaaagatac tacttaatat gaatgttaaa aatataattt tatgtgatag aagtggagca
    11581 ttggaagcta gtatagaaaa tctaaactat gttcaaaaag aaatgttaaa agtaacaaat
    11641 ataagaaatg aaaaaggacc tttaaaagat attataaaag gaaaagatgt atttattggt
    11701 gtttcaggtc caggagctgt tacaaaggaa atggttgaaa gtatgtctga gaagccaata
    11761 atattggcaa tggcaaatcc tactccagag ataatgccag aagaagcaaa attaggtgga
    11821 gcatttataa tgggaacagg tcgttcagac ttccctaatc aagtcaataa tgtactggct
    11881 tttcctggaa tatttagagg tgcacttgat gttaaggcta aagagataaa tgaagaaatg
    11941 aagatagctg ctgcatatgc aattgctaat acaataagtg atgaagaaat atgcccagag
    12001 tatatattac cagatgtatt taataagaat gtagtaaaaa atgttgctaa ggcagttaaa
    12061 gaagcagcga taaaaaccaa agtaaataga atataaattt ttatatgttc atatatcctt
    12121 atcttatcgg gtatatgggc atttttatta taggtttata ctcatatatc cttactttta
    12181 tatacatatc tttatgatta aaggtgttag aaaatgtagt aaattttata ctatcagact
    12241 ctatctttat tactttagta gatacatggt ggtaaaggtt tatagaaaaa aatataggaa
    12301 ggcagatttt tattgttgcg tatatatgag aatgatataa tatgaatatt ataaattaat
    12361 aaatttaaat ttatggaggt acaagagatg atggaatata aagttaatga ccaagaactt
    12421 aatgcttcaa tgtttatccc attcgtcaac aggatatggc caggagatta taatatggat
    12481 aaaacacaga ctgcattatc aaaaactttg aatataactg cttatgatga taaagtgctt
    12541 gtaggatgtc tgcgagttct ttcagatggt tattattttg gaacaattac agaattgctt
    12601 gttcttccag agtatcagaa acaaggcatt ggtagtaagc ttttccagct tgctaaagag
    12661 aacaccccaa ctatgctata ttttggtgca cagccaggag tagaagagtt ctatgaaaaa
    12721 aatgggtgcc aaagaagtct gcaatcctac ataataaaaa agaaagatag ttattaaagt
    12781 tccagctttc aataatctta aaagtacaat attttagtgg aatcatttca ttttttatta
    12841 ctaatatgac ataaacatgt catattagca ttgatatact tttaatatgg ttaagagcca
    12901 aagaaaaata taaggagtga tttaaaatgg aagaaactaa attttgccaa tgctgtgcaa
    12961 tgccaatggg acaaactgat gaattatatg ggacaaataa agatggaagt aaaagtactg
    13021 attattgtag ttattgtttt aaagatggtg agtttacagc tgatataagt atggaagaga
    13081 tgatagaagt ttgtatccct catatgcttc aaagtaataa ggatatgact gaagatgaag
    13141 caagaacaat gatgaacaat ttctttccaa cattaaaacg ctggaaataa ttttatgcaa
    13201 aattagttat atgcaaaaca tgaaatatgg tgttgagaat aaggggtggt gtgctttata
    13261 gcataccacc tgttttgtta cttggagttc agttattttc ctaaatattt taaatatact
    13321 attttagata agttccttct tcatcttgat aaattaatcc ttttttcata agcactccaa
    13381 gagctcgttt aaaatttttc ttacttgaat taaataatat agaaatatct ttagggtcag
    13441 atttatcatt aaatctcata tatccatcag aaccttctaa ataacttaaa atcttatttt
    13501 ctaaagtatc aagttcatcc tttctatttc ctctaggaga aagaccaagt tttccatctt
    13561 catatatttt tatgacatgt aaattttcaa gaacatcacc agtttttagt tcagtaaagt
    13621 actcattatg aagtattaca ccagcatatt tattgtctac acatatcatt gcagaattat
    13681 tagtttggaa tccatataca actccagtta caatatctcc tacattgtaa gtatggtctg
    13741 ttaataagta tgaatctata tctgtagtag cagcaattct tttgcttttg tctaaatata
    13801 tataaaataa atatttttcg tctctaaata gtggataagt cttagcttta aaaggaacta
    13861 atatgtcttt aggaagtccc atatctataa aagtaccaat gtctgtatta tcaactactt
    13921 ttaaatgtgc tacatcccca accttagcta aaggcggtat taaagttgca gcagttctgt
    13981 catcagaatc tttaaatatg aaagcattta cttcatcacc tatgtttatt tcattttttc
    14041 cgattaatct attatgaaga agtatatcgt cttttgtgtt attagtttgt ccatccaaaa
    14101 aatatccaaa ttcagttttt ctttttactg taagtttatt aaaatcacct atgtttatca
    14161 aattaaaatc atcctctcat tttatattta taatttagcc ataatatact tatgtagtag
    14221 tttgtcacag tatctatatt agtattagtg aaatttacaa taaataatat agttatttat
    14281 gtatttttca attctctagc ttcttatata gtataaactc caatttcttt tttgtcttta
    14341 ggttttatta aaatttttac aaaataagtt aaaaagtatt gaaataaaat ttcttttaaa
    14401 gtataattgg tatataccaa aattggtata taccatatcg aaaagtggtg actatatgaa
    14461 aatagtaaat aaatctagta atataccatt gcatactcaa ttaagttcaa taataagaga
    14521 gatgatagaa actggtgagc ttaaagaggg cgatgcaata atgccagaaa gagaactttg
    14581 caacatacaa aatgtaagtc gtatgacagt aaataaaacc attgttggat tagttacaga
    14641 aggacttctt tatagggtac aaggtaaagg gacattcgtt gcaaagcaaa aaaagaagta
    14701 tcagttttca aatgtaaaag gttttactga tgttatgaaa gaaaagggag taaacataaa
    14761 aacggatata ttatcctttg agatggaact accagatgat ttagttaaaa gaaagcttgg
    14821 aataagtgat aatactacaa atatatataa gattgtcaga cttagatata ctgatggaga
    14881 gccatttgga ttagaaatag tatatctatc agaagaaatg tgtaagggtc taacaaaagg
    14941 gatattggat aattcttcat tatatagggt tttaaatgaa aaatatggct ataagataca
    15001 aaaagctgaa caggtaatgg agccagtaat actttcagat gaagaaagta agcttcttga
    15061 aacagatgaa ggtgctttag ctcttaaact tcatagaaat tcctataata gagaaggtag
    15121 ccctatagaa tataccatat caatatttag aacagataaa tatcaatatg aaatagtatt
    15181 gagtgagtag gtgaataata tgaaatgttt aattaatgga aagataatat taaaaaatca
    15241 aatcttagaa aataaagtat tagtatttga tgaaaaaata attgatatag ctgatagtgt
    15301 accaaaagat tgtgaagtta tagatgctga tggaaaatat atatctccag ggcttattga
    15361 tattcatata catggaaaca tgggaaaaga tacaatggat tcgactgatg aatctattga
    15421 aacaatttca aaatcaatta tgagacatgg agtaacatct tttctgccaa ctacaatgac
    15481 tatggataaa gaacatgttt atgatgcact tgaagttatt aaaaaagccc aaaatagaaa
    15541 gcttgaaggg gcaaaggtat taggagcaca tttagaagga ccttttataa atgagaatta
    15601 taagggagca caaaatgaaa aatttataat aaattcaaaa tacgaattta taaaagaata
    15661 taaagatgtt ataaaagtta taacttatgc tccagaaaaa gatattgatt ttgattttac
    15721 tagagaaata aaaagatgta cagatatagt tttatctatt ggtcatagta atgcaaatta
    15781 tgaccaagct aaagaagcta taaatttagg agtaactaat gtaactcaca tgttcaatgc
    15841 aatgactggt ttaaaccata gagacccagg cgttgttggt gcagcactta caactaatgt
    15901 gtacagtgag ttaatagcag atacaatcca tataaataaa gatttatttc aatttatact
    15961 aaataataaa gggaaagaaa gactgatttt aataacagat tctatagaag ctggtggtct
    16021 tgaagatggc aattattctc ttggaggtca gaaagtcata gttaagggta atgaagctag
    16081 acttgaaaat ggagcattag ctggaagtgt gttgtcttta aataaaatgg tatttaactt
    16141 cttagataat acaaacctta aagtgaatga agcaattaat ttagcttctt taaatccagc
    16201 aacatctttg ggaataaatg acaaaaaagg aagcttagaa ataggtaagg atgcagatat
    16261 agctgtattt gatgagaatt tagattgtaa aatgacactt tgcttggggg aagtagtata
    16321 taaaaatata tagtatacaa aacaaacctt aaagacagta aaaacaatat aaaaaataat
    16381 aaattaaact tacattagta aaagtagtag ttaaaattta ggaggaataa gatgagagta
    16441 ttagtgtgta aagattatga tggaatgagt aaaaaagccg ctgaaatgat agcagctcaa
    16501 atagttttaa aaccaaattc aatactggga ctagctacag gaagtacacc agtaggtatg
    16561 tatagagatt tagtaaaaaa atacaatgat aatatagtag atttttcaga tgtgatgagc
    16621 tttaatttag atgaatatta taagttacca atatctaatg accaaagcta tgattatttt
    16681 atgaaagaga atctatttaa tcatgtaaac ataaagccag aaaatactca tctaccaaat
    16741 ggaatggctg atgatattga aaaagagtgt atgaactatg aagcttctat agatgcagct
    16801 ggtggtatag atgtacaagt acttggaata ggtcgtaatg ctcatatagg ttttaatgaa
    16861 cctgatacta aatttgcaaa aagaactcat gtagttgaac ttacagagtc tacaatagaa
    16921 gctaatgcaa gattctttaa atcaagagaa gatgttccta aaaaagctgt aagtatggga
    16981 ataggttcaa tattgaagtc taagaaaata ttgcttttag cttcaggaga agaaaaagct
    17041 gatgcagtat ataatactgt ttacggagat ataactccag aagttcctgg ttctatactt
    17101 caacttcata aagacactat agttatagta gatgaagcag cagcaagtaa actgaatcca
    17161 aaagattata aattagtata agaatagaat gtagtttaag taaaaaatag ctatcattga
    17221 gtaatcaaat ttatttaatg atagctattt ttatttaaat tttttacttc tttttattta
    17281 aattagttat tattgtttaa attacttgct tattactttt tacgaaaact cgttatcaag
    17341 aagtatccaa ataagatgtt aaaaattatt atgtttagtg ggattctatc aagcataata
    17401 aaattaccta taattgggat attaccaact ggaaacataa agaagaatac aggcatcagt
    17461 gatagtaaaa aagatggaaa acaaagaaga agtaatcttg gaatatcaat ataccaacta
    17521 ccatcctttt tgtattctct aatcaataat tcagttccta gtaataaacc aataccacca
    17581 gaggaaatta aattaataaa aatgtatctt ttaaagtctt gcatataacc agtgtgaaat
    17641 tgagtataga aatcataatt taatttaacg gctaaaaaat acataagcaa tagaatgatt
    17701 aaaaataaaa gatatctaag agcttttttc attttaaatt ctcccttcag aaatacttta
    17761 tttagtttta ttttgttgga atctgatttt atcatttagt ttaagaaatc cataatatta
    17821 gtgaagaatg aaataagtat tatatatgaa taaatatttt tagaattaag gtgaattgta
    17881 gtgcttaata taactataat attaattgtt tgaatattca ataaaaagtt tgaaaaatat
    17941 caattttgat ataaactgaa taaatacagt tgaatattaa attattattt tatcaaaaat
    18001 atgcaaagta ctacaccttc aaatatcacc taaagtaatt aaaaggcaat taaggtgaag
    18061 tagttcaagt atttctaaaa taagtttaat aaattctata ataatttatt ttttgcctta
    18121 aaattgcctt aaaatccaaa caattttaaa actaatgtac tataaaaagc tggtataatt
    18181 taaatatagt aaaaaataag atttatctta tctattggga tttaattatt taatcaatat
    18241 atttatacca tttaatttaa ataaaaagtc tattaaggag tgagcttatg agtaagttaa
    18301 tttatatagc agatgatgaa gataatataa gaaatttggt aaagacattc ttaaaaaatg
    18361 aaggtcatga tgttatggat tttaaaacgg gtgatgaact tttagaacaa tttaatataa
    18421 aggagtgtga cttagtaata ctagatataa tgatgcctgg ctcaagtggt tttgaagtat
    18481 gtacaaaact tcgtgagaaa agtacagtcc caataatcat gcttactgca agagatacag
    18541 atatagatta tattacaggg ataaccttag gtagtgatga ttattttaca aaaccattta
    18601 gcccaatgtc tttggttatg agagtaaaat ctatatttag aaggatagag tttgaaaaga
    18661 aacaaaatta tgataaatat agtaactcga tagatatgga attaaaattt ggtgatgtaa
    18721 taataaataa aaagaataaa atcgttacaa gtaaaaatgt aaatatagac cttacaccaa
    18781 atgaatataa cctattgact tatttgtttg aaaatataga tagagcagtt tccagagatg
    18841 aattattaaa caaaatatgg ggatacgata tagaagttga gacaagggct gctgatgata
    18901 cagtgaagag attacgtaaa aaaattttaa atacaaatat tttaatagaa actgtatggg
    18961 ggtttggatt taggttgaag gagaaaagtt aagatgaaga atggaaatga caagaataga
    19021 attggaaaga ttaaatccaa atttaaatta aagttctcaa agaaaaatat aagcataaaa
    19081 actaggattt tgttgagtat actttgtttg ataattatag tatttatgat aatattagta
    19141 tcttttaatg tatttcttga tacatatata aaaacaactg cgaatgaaga attgacaaag
    19201 tctacagaaa tagtagaaca tatggatagt aattttagac ctattaagcc accacaagat
    19261 gatggaaagc ttcctcccaa agtattatct aattttatga gaaatgtaca agataaagtt
    19321 aggatggcag aaacacaatc agatgctgat gctatggtag ttgattctaa gtataacctg
    19381 atatttccaa caagagagga tgatttctta aaaaatgttg atgagatgga gctgattagg
    19441 gagtgtattc aaaatgaaaa attagattta aattcagatg aaaatacacg gatatctacc
    19501 agaaataagg attattatat ttcaactgta aaaattacta gtatatatgg tgaacaagac
    19561 aagtatctta tactttttat agacatatca aaaactctaa atctagcaca aaagataaat
    19621 attgtattaa tatctgtaat gtgttttgct ggaatattag caatatttac agctgtgatt
    19681 ttatctgaga aaattgctaa accgataaaa gagttgtgtg agtttgcaaa aaaaatgggt
    19741 caaggagatt tcaaaagaac ctactttgac ttttcagata aagaattagt agagctctca
    19801 actgttatga ataagagtgc tgagtatctg gataagtatg ataatgaaca aaaaatattt
    19861 tttcaaaatg catctcatga attaaggaca ccacttatgt ctattaaagg ttatgcagaa
    19921 gctataaaat ataatgttat agatagtaaa catgcaagtg atataattct tgaagaaagt
    19981 gataggttaa gtgatatggt tgaagattta ttatacattt ctaaaataga taatataact
    20041 aaagattttg aacttgtaga atgtgattta agagaagtac tttcaaattg tggagctagg
    20101 caaaatgtaa gagctataaa taaggggata gaatttattt atgaatttga tgaagaaatg
    20161 gttttatttg aatgtgatga aaaaaacatt tccaaagcat ttatgaatct tatagaaaat
    20221 gctttgagat acgctaagag tgaaataaaa atagtgtgta agtataatca aaaaaatata
    20281 gttgtgataa tagaagatga tggaattgga atcaagaaag aagatttacc tcatgttttt
    20341 gaaagattct ataagggagt aggaggaaat catggaattg gattatcaat agttaaatct
    20401 attgtaaata agcatggtgg gcgtatatac gtagaaaatg gcaaaaaagg agctaaattt
    20461 actatattat ttaaattgta aaaaaattag agaaaatata gagatgtttg aagttgtttt
    20521 ttatatatat ctgttgtata ctgttgaaaa aagaacaata ttaagctgac atatattacg
    20581 atagttgaca tttaaagtaa atgcttaaat atagatacga aaggaaaagt aaaatctgaa
    20641 gtgtatttag gtttaagtaa gcttcttatt ttataaaaaa tatgtatgaa agaacagctg
    20701 atttttaata ttacaaattt agtaacggtt gtatttgaag cttttgtcat ccatatgttt
    20761 ttatcagact ttttaggcca gaaagaaggg tatataaaag ttgtaagata tgctaaactg
    20821 ggttttataa tatgtttagg attctgtaat ttaataactt taaaccctaa aatcacaatg
    20881 cctttaattt tcatccttat tttttcaaca tcatttttat ataaaggaaa tttaaagaca
    20941 cgattgttta ctactgtttt attaagtata ttctttatac tgtcagaaat tgtagttaca
    21001 agtatttttg ttttatttgt aaaagaaggc tttgaaataa tgcttgaaaa taatagtata
    21061 agagtattgg cgacaatttt atctaaaatt gtctttttgt tgacttgtaa aattatttgt
    21121 ctatttaaaa aggatgtaca tttagatatg cccataaagt attggctccc tttattttta
    21181 atacctatat ttagtttatt tctgtctgtt tctatctttg atgtaagtaa attttttagt
    21241 cttgaaagtt taaaatttct aagcttaata tctagtgttg gtattttata tattaatttt
    21301 attgtctttt atttatttaa atttattata gataaaacta aactatctat gaaatatgaa
    21361 ctacttgaaa aagaaataat tcataaggaa gaattaagac ttagtaatga gtgttataaa
    21421 attattgttg aacagactga ttctgtcgtt ttcgaatgga atatcaaaga aaataaatca
    21481 tttgtatcgc aggcttggac tgaaaaattt ggatataaca atgcatgtaa gaatattttt
    21541 aaagaaatta aagataaaga cttagttcat tctgaagata aagctatatt tgaaggtttt
    21601 cttgaaagta ttaaaaaaaa gaatatgcac aatcaagcag tatatcgttt aaaaaaatct
    21661 aatggtgaat atatttggtg tagaacatca attacaagca tttataatga tgaaaatgaa
    21721 cttttaagag ttgtcggagt aattgtagat gtagatagtg atataaaaaa atatgaagag
    21781 ttaagaacta gagcagaaag tgactcattg accaatatat acaataaagg tacatttgaa
    21841 aaattagtgg aagaaactat agttatgaat acaggtgata aaaaagatgc attattcatt
    21901 attgatttgg atgattttaa agaaataaat gataattttg gtcatccatt tggtgatttt
    21961 gtactaaaaa catttgctga taagatacaa actagttttg gtagtaaaga cttagtcgga
    22021 agaattggtg gagatgaatt tgttgtatat atgcaagatt atgttacaga agtaaatttg
    22081 cataaaaaag ctaaagaatt aaatagagta ctttcggata attacactga tttgagtttt
    22141 agttttgatg cttctgtcag tataggtatt gcaaggtatc ctcaagatgg aacttcattt
    22201 tttgaattgt ttaaaaatgc agatagagca ctttatagca taaaagcatc aggtaaaaat
    22261 tcatattgtt tatttgaaga agaactatat gtacagtgaa tttgaattta gattttatgt
    22321 gagagtaaga tttatatata cttgtggctg tctgatttat aaaatatgtt actttgtata
    22381 tttttatatg tttcagtaag gttaattaac ataagcaaag gtgtaagtaa atttatatta
    22441 gtttaagttt acttacacct ttataaaaat acaaataata gattcattta cattcttaaa
    22501 tgattaaagc tctttacctt ctaaacatgc ataacatatc gttataattc cagtaaataa
    22561 gactaaaatg ccattcctaa gattacagtt tcatcatcta ttactccaaa tgtttttaaa
    22621 gtaacttatt tcgctttgta tcataataat ttatctcctt ttacatttta acttctgctg
    22681 agatttgagt tagatattcg ttagaatctc gcacacttat atcatataga agatattctt
    22741 cataaacaaa atccccaata cgtaaattat tctgattaaa aaaatttaat aacttttcat
    22801 aagtcttgta aatagtttca taactccctt tatgataagc agttacataa agtccctttg
    22861 gtttgattga tacaggatat ttcttgtact ctttattaac ttttgtaaat aaatatgaat
    22921 atgattcaaa gtctttatta attatatctt cacctttaat gattgagcca atcgtaccat
    22981 aatcactcaa ttcatagttg tccataaagt taatacattc atataaaaaa ttttcttcct
    23041 catctcctaa aaattgttct ttatatgtaa caggtgtttt gaccaagtac tcttcttcat
    23101 gttcttttaa agtaatagta ttcgcatcta tattacaggc atttttagtg aatgaaatag
    23161 tagattccat tagagcttga atattattta gtttttcaat ttcattttta atatcaatgg
    23221 ttttcttttc taaaagctca attagtaaat taggtgttct tttgtctata taagctttaa
    23281 tttcttttaa aggcattttt acttccctaa gtgaagaaat tataccaaaa atgctaagtt
    23341 gatggtatga gtagtatcta tatccatttt ctttctttaa ttctggtgag aaaagaccta
    23401 tatcatcata atggaaaagt gtttttttat tgattccaca aatctttgca aattctccag
    23461 ttgtaaaata attttttgaa acttgactca taattataat tcctccttga ctatcctgtt
    23521 acagtatagt ttatcatagt attttgtaaa ggagtgtgat tatatgaaaa aattaattca
    23581 ttttttaaaa ccatatagag ttttaattgt tgtagttttg atatttacgt ttttacaaac
    23641 acttggaact ttgtatatac caacacttac agcaaatata gtaaataatg gtgtagtaaa
    23701 gggagatata gattatattg taaaaacagg tttaatgatg atgatagtag ctggtataac
    23761 agctttatca gctgtgttag tttgtaaagt atcagcaaat ctttcatctg gattttgtag
    23821 agatattaga gaagcagtat ttataaaatc acaagattta tcaataaatg attttaataa
    23881 tataggtaca gcatcaatga ttactaggag tactagtgat attactttaa taggtcagtc
    23941 tgtgtttatg tttattcaat tggtattacc agcaccaatt ataactgttt ctggtctatt
    24001 cttagcatat tctatagata aagcaatgac aattattatt gttgtagtaa tgtttttatt
    24061 catgctttca gcatttttag ttggtaaaaa gcttataaag ttgtttaaaa tgatgcaaat
    24121 aaagatggac aatatgaata gggtgttacg tgaggtagta actggagtaa gagttataag
    24181 agcttttaat aggagtcgtt ttgaaaaaaa gagatttgat agaactgcaa tagattattc
    24241 tgaaacagca atttcaataa ataaaatatt tgcagtactt atgcctattg taatgttaat
    24301 aatgaattta ggtatagtaa gtattatttg gtttggtggg atgagggtca gtaatggaaa
    24361 tatggaaata ggtcatataa tggcacttgt tgaatattgt atcttaattt tattctattt
    24421 aatcatggga gtaatggtat ttatgtacat acctagagca ggtgcatgtg cagatagagt
    24481 aaatcagata ttagatatag aacctgaaat tgtagatgga aatggtcata aagatactgt
    24541 ctcagagaga ggacatttag tatttaaaaa tgtaaccttt tcatatgcac aatcagaaga
    24601 acctgtgtta aataatataa catttgaagc aaaatctgga gaagtaactg caattatagg
    24661 aagcactggc tcaggcaaat ctactattgc aaatataata ccacgttttt ttgaaattca
    24721 atctggagaa atatctataa atggtcagga tattaagaag attcctcaaa aagaacttag
    24781 agataagatt ggatttgtac cacaaaaagc ttttttattt agtggaacaa tagaagaaaa
    24841 tataaggtat ggaaaagaag atgcaagtat tgaagaagta aagcatgctg caagtatagc
    24901 tcaagctgat gaatttattt ctgatatgga agacaagtat gactcatttg tagcacaagg
    24961 tggaaataat ttgtcaggtg gtcaaaaaca gagaatatcc attgcaagag cgttagttag
    25021 aaagcctgaa gtatatgtct ttgatgatag tttttctgca ttagatttta aaacagataa
    25081 aagacttaga aaagcgttga aaaatgaaat caaagattca tcagctataa ttatagcaca
    25141 acgtataagt acaatcatgg atgctaatca gattatagtt ttaaatgatg gaaaaattgt
    25201 aggtattgga aaacataaag atttacttga aaattgtgaa gtttataagc aaattgcgga
    25261 ttcacaactt agtaaagaag aacttgcata aaatgaagaa ttaatctgat atttggaggt
    25321 gtatgatatg agtgaaaaaa gaatagatga acaagatata gaagtactta gttttgaaga
    25381 tggcatgtca gcagaaaaag ctaaggatgc aaaaaaaact actaagagat tattaaaata
    25441 tatggcaaaa caaaagttta aaatattaat tatttttatt tcagtattga taagttcagc
    25501 gcttacagtt ttagcaccta tggttatggg aaaagctatt gaccaactat ttaatggaat
    25561 aaaaactgca gtccaaacag gtacaaaatt cagtgtgaat tttagtacta tgggagggat
    25621 agtatcaata cttctagggt tgtacttaat tagtgcagta tttatatata ttcaacagta
    25681 tattatgtca ggagttgcac aaaatctagt tcttagcatg agaaaagatt taagtgataa
    25741 actcaataaa cttcctctta agtactatga ttctcataaa aagggggaaa cacttagtat
    25801 agtaacaaat gatttagaaa aagtagcaga tagtttacaa gaaggattaa tgcaacttat
    25861 tacagcagta gttacagtag ttggttctat tgtaatgatg ataagtataa gtgtaccact
    25921 tacaatagta tcagctataa cattacttgt ttcattgggt attactgttg taattgcaag
    25981 aaaatcacaa gaaagattct ctgaaaatca aaaggcacta ggagagttaa atagcaatat
    26041 agaagagata tttactggtc aaatagtggt taaagcattt agtaaagaaa aggatactat
    26101 aagaaacttt aaaatattaa atcaaaatct ttataatgca agtagaaaag cacagttttc
    26161 gtcatatgca atatctccaa ttattagatt tataaaccta attggctatg ttattatagc
    26221 agttgtaggt gggatatttg catcaactgg agcaatgact cttggtagta tacaagcgtt
    26281 tattcaatat gtaaatcaag catcagagcc tactacagaa atatcttata ttgtaaatat
    26341 gcttcaagca gcaatagcat ctgcagagag agtttttaca gttatggacg aggtggaaga
    26401 gataaaggat gaagaatctt caaaggttat tagcatgcct aaaggtaaag tacaatttga
    26461 gcatgttaaa tttggatata gtgatgattt tattcttatg aaagatatta atatcaatct
    26521 aaatgcagga gataagattg caattgttgg acctacagga gctggaaaga caactcttgt
    26581 aaatttactt atgagatttt atgagataca aggtggaaga attactattg atggtgttaa
    26641 tataaaagat ttaaagcgtg gagaacttag aactatgttt ggtatggttc ttcaagatac
    26701 atggctgttt aatggaagta taaaagaaaa tattgcatat agtaagtcag atgccacaat
    26761 ggatgaaatt gtaagagcag caaaatcagc aagagtagac cattttataa ggactttacc
    26821 acaagggtat gacactatat tgactgagga tgcttctaat ctatctcaag gtcaaaagca
    26881 acttctaaca attgccaggg caatactttc agacccatca gtattgattc ttgatgaagc
    26941 aacatctagt gtagatacta gaacagaggt agaaattcaa aaggcaatga ataacttgat
    27001 gaagggaaga actagttttg ttattgcaca tagattatca actattcgag atgctgattt
    27061 aatattagta atgaaagaag gaactattat tgaacaagga agccataagg aacttattga
    27121 aaagaaagga ttctatgaag aactttataa cagtcaattt acaagtgaat atgatgaaga
    27181 tgttgtatga ttatcaagtt ttaggcaact aaatgattga taaatattaa gttaaatata
    27241 gtaacatgta aggttatatg gaataagagt atttctctat ttcatataac cttttttatt
    27301 tatcaaaata agataaaatt tcctttctaa attagattga agaatgtatt tatcaatata
    27361 aaagtaaaat aatcattatt attagtgaag taaatattgt ttgccacata tatgccataa
    27421 agatgcactt attttacgga gatttaacaa agtagtgtaa agtatactct aaatataaaa
    27481 taaatcaaat agagttaaat aaattgagag gtgatataaa tagtgaataa aaaattgaac
    27541 tatagatttg aaatgaagca caaaataact gaagcagatg tgttagcttt aaaatcaaga
    27601 ctctatccaa taatgaagaa agatgaaaat gcatctaaag atggaaaata tcttattagg
    27661 agtttatatt ttgatactcc tgaagataaa gcacttttgg ataaattaaa tggcgttgca
    27721 ataagagaaa agtttaggat aagattttat aataatgact gctcttatat aaggttagag
    27781 aaaaaaatca aacattacaa catgacatca aagctatcaa ctaatttaac caaaaaagaa
    27841 gtaataaata tactaaataa tgatattgaa tttctaaaag agtcgacaaa ttgtttatta
    27901 agagaatttt atttgaaatt aaaatgtgaa agattagagg caaaaagcat agttgattac
    27961 aatagagaag cttttattta tccagttgga aatgtaagag ttacaatcga tagtgatatt
    28021 aaaacttctg taaattcggt agatttattt aataaagatt tgccaactat ttcggtaatt
    28081 gatgagaata tgactgtatt ggaggttaaa tatgatgaat ttataccaga ttttataaag
    28141 gatttaattc aaattaataa gactacctct acagcagttt caaagtatgc ttcaagtaga
    28201 ttatatattt aagaataaag gctatgattt atataaagat atacataaat aaggttaaaa
    28261 aacaaataag ttaaaaataa ataaaataaa aaataaataa gttaaaaata ggaaggatga
    28321 ttttaattat gacatttaat gatattttta aatcaagttt tatagaaaac gtatcaggtt
    28381 tttcatttgt ggacagtgct ttagcactag gttcagcttt tttagtaggt ttgtttatat
    28441 atatggtcta taaaaagact tatatgggaa ttatgtattc tcgaccattc aatgtgtcgc
    28501 ttgtagcact tacaatgctt acaacttttg taatattggc ggttacttca aatgtagttt
    28561 tatccttagg tatggttggt gctttatcta tagtaagatt tagaacagca attaaagacc
    28621 caatggattt agtatttcta ttttggtcat taggttcagg tatagtttta ggagcaggtt
    28681 tgattccctt agctgtcatg ggttcaataa ttatgggatt gattctaata ttcttttcaa
    28741 ataaaacaat atctgaaact ccatatatat tgatggtaaa ttgtaataat gaagattcag
    28801 aagatatagc aactgataaa attaaaaaag tatttactaa atatcaaata aaatcaaaaa
    28861 gtgttacacc agaaaaagga atagaattag tgtttgaagt aagaatgaaa gatggagaaa
    28921 caagtcttat aaatgacttg agtcaagtag atggagttac taatgcagtt cttgtaagtt
    28981 ataatggtga ctatgtagca tagagaggag taatctttta tgaaagataa aaaatttacc
    29041 cttcttatct cgattatgat tatattttta tgtgctgtag ttggagttta tagtacatct
    29101 agcaacaaaa gtgctgattt atatagtgat gtatatattg aaaaatattt taacagagac
    29161 aaggttatgg aagttaatat agagatagat gaaagtgact tgaaggatat gaatgaaaat
    29221 gctataaaag aagaatttaa ggttgcaaaa gtaactgtag atggagatac atatggaaac
    29281 gtaggtataa gaactaaagg aaattcaagt cttatatctg tagcaaatag tgatagtgat
    29341 agatacagct ataagattaa ttttgataag tataatacta gtcaaagtat ggaagggctt
    29401 actcaattaa atcttaataa ctgttactct gacccatctt atatgagaga gtttttaaca
    29461 tatagtattt gcgaggaaat gggattagcg actccagaat ttgcatatgc taaagtctct
    29521 ataaatggcg aatatcatgg tttgtatttg gcagtagaag gattaaaaga gtcttatctt
    29581 gaaaataatt ttggtaatgt aactggagac ttatataagt cagatgaagg aagctcgttg
    29641 caatataaag gagatgaccc agaaagttac tcaaacttaa tcgttgaaag tgataaaaag
    29701 acagctgatt ggtctaaaat cacaaaacta ttaaaatctt tggatacagg tgaagatatt
    29761 gaaaaatatc ttgatgtaga ttctgtcctt aaaaatatag caataaatac agctttatta
    29821 aaccttgata gctatcaagg gagttttgcc cataactatt atttatatga gcaagatgga
    29881 gtattttcta tgttaccatg ggattttaat atgtcatttg gtggatttag tggttttggt
    29941 ggaggtagtc aatctatagc aattgatgaa cctacgacag gtaatttaga agacagacct
    30001 ctcatatcct cgttattaaa aaatgagaca tacaaaacaa aataccataa atatctggaa
    30061 gagatagtaa caaaatacct agattcagac tatttagaga atatgacaac aaaattgcat
    30121 gacatgatag catcatatgt aaaagaagac ccaacagcat tttatactta tgaagaattt
    30181 gaaaaaaata taacatcttc aattgaagat tctagtgata ataagggatt tggtaataaa
    30241 gggtttgaca acaataactc taataacagt gattctaata ataattctaa tagtgaaaat
    30301 aagcgctctg gaaatcaaag tgatgaaaaa gaagttaatg ctgaattaac atcaagcgta
    30361 gtcaaagcta atacagataa tgaaactaaa aataaaacta caaatgatag tgaaagtaag
    30421 aataatacag ataaagataa aagtggaaat gataataatc aaaagctaga aggtcctatg
    30481 ggtaaaggag gtaagtcaat accaggggtt ttggaagttg cagaagatat gagtaaaact
    30541 ataaaatctc aattaagtgg agaaacttct tcgacaaagc aaaactctgg tgatgaaagt
    30601 tcaagtggaa ttaaaggtag tgaaaagttt gatgaggata tgagtggtat gccagaacca
    30661 cctgagggaa tggatggtaa aatgccacca ggaatgggta atatggataa gggagatatg
    30721 aatggtaaaa atggcaatat gaatatggat agaaatcaag ataatccaag agaagctgga
    30781 ggttttggca atagaggagg aggctctgtg agtaaaacaa caacatactt caaattaatt
    30841 ttaggtggag cttcaatgat aataatgtcg attatgttag ttggtgtatc aagggtaaag
    30901 agaagaagat ttataaagtc aaaataagat taaaattgaa tataaataat tttaatactg
    30961 ttaagtctaa atatttactt agcagtattt ttttagaaaa taatgtattt ggttaataat
    31021 ataaggtaat aaattgataa aaattaaata cagcatatta ataatacata ataaagtaat
    31081 aaaaaaactg tttaagtata ataacttata tttagacagt ttttttcatt tataaataat
    31141 ataaatgaaa ttgaaaacat ttgaaggata gaaattggtt ggataaatgt ataaattact
    31201 tcaccaaaaa ataatgacaa aaattgtaac taagttgtaa taaaatggta gttatttagc
    31261 ataaaataat gtatcataga agtatattat aaaattaata aaataagatt tttgtaagaa
    31321 aactgctggc ttttgatatt tagagtgagt agttaaatta tgtttaggag gggtagaatt
    31381 tgttgcaaaa agtattatgg aaatttttaa agctagtagt cggtttattt atatgttcag
    31441 ttggtatagt attgacgata aattgtaacc ttggattatc tccctgggat gtatttcatc
    31501 aaggactttc aaatcatata ggaataacta taggaactgc ttctataatt gtaggctcta
    31561 tagtagttat tgctgatgtc gttcttggag aaaatgtagg atggggaact gtttttaaca
    31621 tgctactaat tggattcttt atggatttac ttttatatag taatttaatt ccagaggctg
    31681 atagtttatt tgtaggaata attatgttga tattaggatt ggttcttttg tctgttggaa
    31741 tggtatttta tatgggaagt ggtttaggaa gtggacctag agatggtttg atggttgcaa
    31801 ttcaaaagaa aacaggaaaa tcacttaaat taataagagg tactatagaa gttggagcat
    31861 taatagtagg atttttatta ggtggaaaag ttggtatagg aactataata agtgcatttg
    31921 gattggggta tttcacacaa atggtatttg gcttatttaa attagattgt agtaagatta
    31981 aacatagatt tatagtagat gatataaaat ttatcaaagt gtatatgagt ggtgagaaaa
    32041 aagctgctgt tcaaaatata gttaagtaat ttaagaataa attcaacgaa atgttaagta
    32101 ttttaaatta acattttgtt tagatagata aattgaatat taaaagaata ttaaaatatg
    32161 aggattgcta gaacactata aaatatagat ttctagcaat tttttatttg ttcaatattt
    32221 ttttagtact agaagtctta ttctctattt aatgaatgaa ttaatttata attagagata
    32281 ctaaacttta tagatattaa tataaacacc tttaaactgt gtattttcca aagcctttaa
    32341 aatgcttgta tttattctaa ataaaaaaat aaaaaaatgt caaaaaaact cttgtattat
    32401 atccaaattt tatatataat tacctatgtt gtttagaaat tttaaactca atgtttagta
    32461 aacaaaatgt ttagtaaaat aaaacagaaa ctaggaggtg caacatggat ataggtgaaa
    32521 agataaaaag attaagaaca gaaaaacaac tgacccagga agagttagct aatagatgtg
    32581 aattgtcaaa gggatttatt tctcaattag aaaataactt aacatcacca tccatagcta
    32641 cccttataga tatacttgaa atactaggta caaatttaag ggaatttttt aatgaaatag
    32701 atgatgaaag aatcagtttt acaaaagaag atatgtttga aacagaagat gaagatttaa
    32761 aatataaatt aaagtggtta attccaaatt cacaaaaaaa tgaaatggag ccaataataa
    32821 taacattgta tccaggagga cagtataaag aagaaaagcc acatgaaggt gaagaatttg
    32881 gatatgtatt agcaggttca atatatgtcc atataggcga aaagaaaaat aaagtaaaaa
    32941 aaggagagag tttttacttt agaccgaaag caaatcacta tatatcaaac gagggcaaaa
    33001 ctacagcaaa agtgatttgg gtaagtacgc caccatcatt ttagaataga ggtgtttaat
    33061 aattggtaga aaatataata gaattaaggg atatatctaa acattatgaa gaacttactg
    33121 ttttagataa tttcaattta gatataaaga aaaatgagtt tctaacatta cttggaccaa
    33181 gtggatgtgg aaaaactaca acattaaaaa taatagcagg atttgagtat gctgatgatg
    33241 gtaaagtttt atttgaaggt aaggagataa ataatttgcc accatatgaa agacaagtaa
    33301 acacagtatt tcaaaaatat gctttatttc cacacatgga tgtttatgaa aatgtagctt
    33361 ttggattaaa aattaaaaag actccaaaag atgtaataga tgctaaagta aaagaggttt
    33421 tgaaacttgt tgcactagaa ggttttgaaa gacgacaagt tgaatcattg agtggaggac
    33481 aacaacaaag aattgcaata gcaagagctc tagttaatga accaaaggta ttattactag
    33541 atgaaccact tggagcactt gatttaaagt taagacaaga gatgcaaata gaattaaaga
    33601 gaatccaaaa aaaattagga ataacatttg tttttgtaac tcatgaccaa gaagaggctc
    33661 ttactatgtc agatactatt gttgtaatgt ataagggcaa aattcaacaa atgggaacac
    33721 cacaagatat atacaatgaa cctaaaaatt catttgtagc taagtttata ggtgaaagta
    33781 acatatttga tggaattatg atagaagatt ataaagttaa tttctgtaat agagattttg
    33841 agtgtgttga taaaggattc gaaaaaaacg aaaatataga agtagtaata agaccagaag
    33901 atataaaaat ggtaaagcca gaagaaggaa tgttaaaggg gaaagttaca tctacagtgt
    33961 ttaaaggagt gcattacgag atagaattga atgaaaatgg aagattgtgg atacttcata
    34021 atactaaaaa tgctgaggtt gggactgaac taggcatgga tatatatcca gaagatatcc
    34081 atataatgag aaaagagaat aactaagatg aaaagaaaat cttttttagc atatccatat
    34141 gtagtttgga gtgcgatatt tgtaataatt cctttaatat tagtagtatt ttttagtttt
    34201 acaaaagaat caggtggagg ttatgccttt acacttgaga attataaaga agtaattgac
    34261 cctatatata tgaaagtttt tgggcgttct attcttttag caggaggagc tacattaata
    34321 tgccttatag ttggttatcc agtggcatat ataatttcaa aggctcgtgt aagtagaaga
    34381 ggttcattaa tattattgtt tattcttcct atgtggatga actttctttt aagaacatat
    34441 gcatgggttg ctatattagg aaaaaatgga cttttaaata catttttagg ttggtttgga
    34501 atacaaccat tagcaatttt gtatactaat tttgccatac ttttaggtat ggtgtataac
    34561 tttttaccat ttatggttct tccaatatat acagcactat caaagatgga taatgatttg
    34621 ataaacgctg ctcatgactt gggtgcaaat aatatgacag tttttagaaa aattatattt
    34681 cctttgagtt tgccaggtgt aatgtctgga ataactatgg tatttatgcc agcagtcact
    34741 acttttgcaa tatcaagact gttaggtgga ggtaaaataa tgctggttgg agatttgatt
    34801 gaacaacagt ttacagttgt tggagattgg aactttggtt cagctatatc gatatttatg
    34861 atgatagtaa tattaatatc tatgtctata atgtcaaaat ttggagatga atctgacaaa
    34921 gaaggcggtg ggttactatt ttaaaattaa agaaaataac ttctaatata tatttagcat
    34981 tagtattctt atttttgtat gcacccatat ttgctttggt actattttct ttcaatgatt
    35041 caaaatcaat ggcaagatgg aatggattta catggaagtg gtatggtcaa ttacttcaaa
    35101 atgagagtat aatgagtgct ttatattata ctattgtaat agctatatta gcgtctgtaa
    35161 tatctacaat agtaggaact ataagtgcta taggaataca taagatgaga ggtaagagta
    35221 agaaattaat actaaatgta aactatcttc ctattttaaa tacagagata gttacagcag
    35281 tagctcttat gagtctgttt gtatttgtaa aaatggaatt tggatttaca acaatgctat
    35341 tggcacatat aatgttttgt ttgccatacg ttatactttc agttttgcca aaaatgaagc
    35401 aattacctga taatatagaa gatgcagcta tggacttggg agcaacacct atatacgctc
    35461 ttagaaaagt aattttacca caaataaaac caggtatagt ttctggattt ttaattgcat
    35521 ttactatgtc aatagatgac tttataataa gtttctttaa tgctggaaat ggtgtaagca
    35581 atctttctat agaaatctat ggaatggcta gaagaggtat aaaacctgaa ataaatgcat
    35641 tatcaacaat aatgtttgca gtggttctag gtttactttt actagctaat aaaaaagaat
    35701 ctatagtaag ggggattaaa taatgattaa gtttaaaaaa gcaatatccc ttatagctgt
    35761 aggtatgatg acagttactt tatttacagg atgtaataaa gcaactgatt ctacaaaagt
    35821 tttaaatgta tataatgttg gagattatat agatgagtct cttatagata agtttgaaaa
    35881 agaaacagga atagatgttc aatattcaac ttatgatact aatgaaatga tgtatcaaaa
    35941 agtaaagagt ggtagtacac actatgattt agtatttcct tcagactata tggtagagaa
    36001 aatgaaaaat gaaggtcttt tggaaaaatt agattttaag aatataccta atatgaaata
    36061 tttagataag agttttttaa atcctgtata cgacaaaact aatgaatata gtgttgcata
    36121 tatgtgggga actcttggaa tactgtacaa taagaaagaa gttaaagacc ctatggatag
    36181 ctggaatata ctttggaatc caaagtataa gggaaatata atgatgtttg actctgttag
    36241 agatactata gggataactc ttaaaaaatt aggatatagc atgaatagtg taaatccaaa
    36301 agaaataaat gaagctaaaa atcttttaat gaaacaaaag gatttagtat tggcttatgt
    36361 aaatgatgaa ggtaaggata gattgcttgg tggagaagtg gcaatgggta tgctgtattc
    36421 tggagatgca gttacactaa tggagcaaaa tcctgacctt gattatgcta tacctaaaga
    36481 gggaactaat aaatgggtag atgctatgtg tgtacctaca acagcacaaa ataagaaaga
    36541 agctgagctg tttataaact ttttattaga cccagagaat gcaaaagtaa atgctgagta
    36601 cattgggtat tcaacaccta atacaggagc actaaaatta ttagacccag aaataactca
    36661 gaatcctgtt gcatatccat ctaaagaagt gcttgataaa tgtgaaactt ttgaagatat
    36721 tggtgaaaat ataaaattat atgacaaggc ttggatagag ttaaaatcaa aatagggtct
    36781 tgttggttta agtaaattta cttaataaat acttaataaa actgttcttt tttagaaaat
    36841 ttattttcta attattgaac agttttattt tttgtttaag ttatattcat atgcaattta
    36901 aatagtttat taataaatga aaacttattt gtataatgac tttaataata attagaaaaa
    36961 atgggcaact taatagaata attggaggtg taaatttata aaaaatgaat aggataaata
    37021 aaaaaataga tttattaata ttggctttgc tcgtttttat atttttaatt gttggaatag
    37081 taatactatc gattaggaca gaaaataaat tgaatgtgtt cataatgtta gcaataattt
    37141 tttttataat aatgttaact tatttatcaa attcagtagt ggggttgata acaagttcaa
    37201 taattatatt tatgtataca tcctatattt tatataacaa tattactcac aatatggatg
    37261 ttgaatttat atcatatatg tggataatag caacaccagt atcttcaatt ataatgggta
    37321 atctgaacaa aagcataaat gaattgcaaa atacaaataa aaaactatct gaacagtata
    37381 aggaattagt gactattgat agtgaaactg gacttagaaa tttaaagatt ttttataatg
    37441 atgtaaatat ggagataagt aaatctatta gacataatac tgatttttct cttatgatag
    37501 taaaattacc atactacgga aacctacaga ctatatttgg tgaaaacaaa actaataaaa
    37561 tagtaaaata tattggttca aatattatag aatgtacaag aaatgaagat ataatttata
    37621 gtttacaaaa agatatgata gggatactaa tgccaaatac atctttggaa ggttcaaaag
    37681 ttgttaaaga cagaataaag aaaaggataa aagaattaaa tttagattta aacaataggg
    37741 gaaaatatgt aaatatagat gtcaaaattg catttttaca atataagagt agttttggag
    37801 atagtataaa ttttaagaat atagttgaag aggaacttca atatgatgtt taaaatattt
    37861 aataaaagtc tattaaaatt agtagttgta ttatcaatag tactgacaat atcaaatttt
    37921 agcttatctt catatgcatc agaaattact tccagcacag ataaggtatt aatcatatat
    37981 gattctaaga aagaaacagc ttataataga gatattttaa atattatgag gactctattg
    38041 ggaagattta gttcagatat agagctatta aaattgagta actatgatgg tgagataaat
    38101 aaaaattatt acagtcatat atttatttta ggaatcaatg aaaactcata taataatgat
    38161 aaaaacacta aaaacttgat tagttcctta aatttatata aaggaactat atgttggtta
    38221 ggatatggta tagaaaatct tttggaacat aaaaaataca atttagacta tgtaggaaaa
    38281 acaaacaata tagttagtgt aaattataga ggtaaatcat ataacttgga tgaacattat
    38341 gtttttaaca ttgtagaatc aaaagataca agtaataaag taataggaag tattaatgat
    38401 accttaaata agtatccata tataataaat gataaaaatc ttttttatgt atcaaaatta
    38461 gatttagatg gagttttatt ttatatattt tgcgattcac ttaatgatat ttttaatatt
    38521 aagacgtttg ataaaggacg tatatttgta agaatagaag atgtacatgc ttttagagaa
    38581 ccaaaaaatc ttgtagagat agcggattat ttaagtagta agaatatacc atttacgatt
    38641 gcattaatac cagcatatgt aaatcctaaa aatcataagg taataacttt atcagaaagc
    38701 cctgaaattg tcaaagcaat aaaatatatg caagataaag gtggaactgt gatattgcat
    38761 ggatatactc atcaatacaa gaaagaagaa gtttctggag aagggtatga attttgggat
    38821 ggtaaaaaag atgaaccctt aaaagaaaat atgaagatat ttgtcaaaga tagagttttg
    38881 aatggtctta gagtatgtat agagaatgga atttatcctc ttgcatttga agcgccacat
    38941 tatgcaatgg aatcagaggg atataaagaa ttaaaaaaat atttttctac ttatataggg
    39001 caacatcaaa ataatgataa aaaatttagc acaaatacat atccttatat tattagggat
    39061 acagaggagt ttaatatatt tatacccgaa aatttaggat atatagaccc agaagataag
    39121 tttacttttc aaaatataaa agaaaattta aataaattat ccattgtaag aggttttagt
    39181 ggagggttct tctttcattc atatttaaac atagagtatc taaaaaacac aatagaatat
    39241 ttagaaaaac agaatataga atttatgaat ttaagagatt ttaataattg ggtaaaagtt
    39301 gatgaaatac aaataagaaa taatggagat gaaattatag tcaactatga taaggactta
    39361 gatgaactaa ctaaaagtga tactagattt aaatccatat ccaatattag taaaatttta
    39421 atattcatag tatctataag tgttttaata tttgtgatta tatttat
//
LOCUS       DAEPXW010000033        39001 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.034, whole genome shotgun sequence.
ACCESSION   DAEPXW010000033 DAEPXW010000000
VERSION     DAEPXW010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39001
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.034"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            41..1897
                     /locus_tag="KRM55_001626"
     CDS             41..1897
                     /locus_tag="KRM55_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH1593875.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGTYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDTEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    1980..2220
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    2286..2521
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2606..3823
                     /locus_tag="KRM55_001627"
     CDS             2606..3823
                     /locus_tag="KRM55_001627"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH1593876.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            3940..4434
                     /gene="cdeM"
                     /locus_tag="KRM55_001628"
     CDS             3940..4434
                     /gene="cdeM"
                     /locus_tag="KRM55_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBH1593877.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGENRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            4699..5964
                     /gene="hisD"
                     /locus_tag="KRM55_001629"
     CDS             4699..5964
                     /gene="hisD"
                     /locus_tag="KRM55_001629"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBH1593878.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(6167..6919)
                     /locus_tag="KRM55_001630"
     CDS             complement(6167..6919)
                     /locus_tag="KRM55_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1593879.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(7037..7306)
                     /locus_tag="KRM55_001631"
     CDS             complement(7037..7306)
                     /locus_tag="KRM55_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593880.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            7781..8875
                     /locus_tag="KRM55_001632"
     CDS             7781..8875
                     /locus_tag="KRM55_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH1593881.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISNITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            8877..9827
                     /locus_tag="KRM55_001633"
     CDS             8877..9827
                     /locus_tag="KRM55_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBH1593882.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILIKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            9820..11004
                     /locus_tag="KRM55_001634"
     CDS             9820..11004
                     /locus_tag="KRM55_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593883.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLNCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISNYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGNVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIIAPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            11017..12513
                     /locus_tag="KRM55_001635"
     CDS             11017..12513
                     /locus_tag="KRM55_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH1593884.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            12536..13486
                     /locus_tag="KRM55_001636"
     CDS             12536..13486
                     /locus_tag="KRM55_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593885.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMFLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            13507..14469
                     /locus_tag="KRM55_001637"
     CDS             13507..14469
                     /locus_tag="KRM55_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH1593886.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            14841..15473
                     /locus_tag="KRM55_001638"
     CDS             14841..15473
                     /locus_tag="KRM55_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1593887.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            15884..15976
                     /gene="kdpF"
                     /locus_tag="KRM55_001639"
     CDS             15884..15976
                     /gene="kdpF"
                     /locus_tag="KRM55_001639"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBH1593888.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            16017..17699
                     /gene="kdpA"
                     /locus_tag="KRM55_001640"
     CDS             16017..17699
                     /gene="kdpA"
                     /locus_tag="KRM55_001640"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBH1593889.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSIHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            17724..19781
                     /gene="kdpB"
                     /locus_tag="KRM55_001641"
     CDS             17724..19781
                     /gene="kdpB"
                     /locus_tag="KRM55_001641"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBH1593890.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            19800..20426
                     /locus_tag="KRM55_001642"
     CDS             19800..20426
                     /locus_tag="KRM55_001642"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBH1593891.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            20663..21571
                     /gene="cysK"
                     /locus_tag="KRM55_001643"
     CDS             20663..21571
                     /gene="cysK"
                     /locus_tag="KRM55_001643"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBH1593892.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            21598..22188
                     /gene="cysE"
                     /locus_tag="KRM55_001644"
     CDS             21598..22188
                     /gene="cysE"
                     /locus_tag="KRM55_001644"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBH1593893.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            22348..22536
                     /locus_tag="KRM55_001645"
     CDS             22348..22536
                     /locus_tag="KRM55_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH1593894.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(22590..23459)
                     /locus_tag="KRM55_001646"
     CDS             complement(22590..23459)
                     /locus_tag="KRM55_001646"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBH1593895.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDVINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(23656..24900)
                     /locus_tag="KRM55_001647"
     CDS             complement(23656..24900)
                     /locus_tag="KRM55_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593896.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            25191..25502
                     /locus_tag="KRM55_001648"
     CDS             25191..25502
                     /locus_tag="KRM55_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH1593897.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      25595..25687
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            25787..26581
                     /gene="thiD"
                     /locus_tag="KRM55_001649"
     CDS             25787..26581
                     /gene="thiD"
                     /locus_tag="KRM55_001649"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBH1593898.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            26605..27393
                     /gene="thiM"
                     /locus_tag="KRM55_001650"
     CDS             26605..27393
                     /gene="thiM"
                     /locus_tag="KRM55_001650"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBH1593899.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            27416..28048
                     /gene="thiE"
                     /locus_tag="KRM55_001651"
     CDS             27416..28048
                     /gene="thiE"
                     /locus_tag="KRM55_001651"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH1593900.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMSFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            28187..28489
                     /locus_tag="KRM55_001652"
     CDS             28187..28489
                     /locus_tag="KRM55_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1593901.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(28555..29304)
                     /locus_tag="KRM55_001653"
     CDS             complement(28555..29304)
                     /locus_tag="KRM55_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593902.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(29298..30260)
                     /locus_tag="KRM55_001654"
     CDS             complement(29298..30260)
                     /locus_tag="KRM55_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593903.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(30264..30722)
                     /locus_tag="KRM55_001655"
     CDS             complement(30264..30722)
                     /locus_tag="KRM55_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1593904.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            31078..31434
                     /locus_tag="KRM55_001656"
     CDS             31078..31434
                     /locus_tag="KRM55_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1593905.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            31506..32222
                     /locus_tag="KRM55_001657"
     CDS             31506..32222
                     /locus_tag="KRM55_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1593906.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            32215..33039
                     /locus_tag="KRM55_001658"
     CDS             32215..33039
                     /locus_tag="KRM55_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1593907.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYVFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            33051..34250
                     /locus_tag="KRM55_001659"
     CDS             33051..34250
                     /locus_tag="KRM55_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593908.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILSSKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            34259..35071
                     /locus_tag="KRM55_001660"
     CDS             34259..35071
                     /locus_tag="KRM55_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593909.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTELWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            35082..36350
                     /locus_tag="KRM55_001661"
     CDS             35082..36350
                     /locus_tag="KRM55_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593910.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            36716..37897
                     /locus_tag="KRM55_001662"
     CDS             36716..37897
                     /locus_tag="KRM55_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1593911.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(38039..38956)
                     /locus_tag="KRM55_001663"
     CDS             complement(38039..38956)
                     /locus_tag="KRM55_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593912.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
BASE COUNT        15163 a         4185 c         6748 g        12905 t
ORIGIN      
        1 agtattatta taaataacat tgaaaggtag tggttagaat atggataccc ataataaata
       61 tgtaaatttt ataaaaaata tacctgtacc ttttttatat tgtagaattg taaagagaca
      121 agaagatata gaatatcgag tagaatatat aagtaagggt atgggcaaag tattacaatt
      181 agaagaaggt atttgtgata aaaatatact agatgtattg cctgtattta agtctaaaaa
      241 atatttcaaa gagttgttct caaatgaagt ggattgtata aaaaggtaca ttccgacact
      301 taaaaattgg ataaatataa aaaaacagat aataggggat tcatacataa ttttgtattt
      361 tggtaaaatt gtatttgatt atagacagat aatcgattcc tttgataaaa aggaaaaagt
      421 agcttatatt aaagacgaag aaggcacata tatagattgc agtgaaaatt taataccaat
      481 attaaataac aacattaaaa caacgaaaga tatctttggt aaaaatgata tagaagtatg
      541 gggagagaat acaggaaaat tatttagaga tgattataga gaaggagtat ctagtaaaaa
      601 aagattttta caaaatcttt ttgaatatga agaaacattt tttatggttg aaaaatattt
      661 tttgtatgat gaagacgaac ttttaggtac tatagggata gtagacaata taatatatag
      721 tggttacagt aatagaaatt ataactcaaa agatttaatg aagatgatag aacactcaat
      781 tccagagaat atgttttata aagatgtgta tggaaattat attggattta attcaggttt
      841 tttgaattta gcttgtatga ataaagaaga attattaggg aagaatagtt ataaaatatc
      901 agaagaagaa gctttaatag ataagatatt tgaaagtgat aagggtgtag ttgaaaataa
      961 aaaagtagtt acatttgagt taaatataag tatgaatgat gaaaacaagt gtattgagat
     1021 tacaaaaagg ccgttttttg atagctatgg aagtgttatt ggaataattg gaacagcaag
     1081 ggatataagt agaagaaaaa gattagaaga ggaaatggat aaaactagga tggaattttt
     1141 tgcaaattta tcccatgaac ttagaacgcc tataaactta atatcatctt cattacaagt
     1201 gatagaaaaa aaagaagcag atttaataga atcaaatgat actttaaaaa gaaatttagg
     1261 tataataaaa caaaatggaa atagaatact gaggttagta aataatgtta tagattttac
     1321 aaaaatgcaa tcaggatatt tagattttaa accagaagaa tctgatataa ttgcatttat
     1381 agaggagata tgtatgtctg tagctgattt tgcaagccaa aataatatac aacttacatt
     1441 tgatacagaa atagaagaat tttcaatgtt atttgataca gaaaaattgg aaagaataat
     1501 attaaattta ctttctaatg gaattaagta caataagaaa gatggaaaaa taaatatatt
     1561 tttatatgtg aaagataatg tatttaatat gaaaatatct gatagtggaa taggaatacc
     1621 aaaagaaaaa atagataaaa tatttaatag gtttgaacag attgacaatg aactttctta
     1681 cagagttaaa ggaagtggta ttggactttc attagtgaaa tctttggttg agttgcatga
     1741 gggaagtata tctttaaaaa gtcaacttgg tattggaagt gaatttatag tttcattgcc
     1801 tgttagaagt aaaaataata ttgaaaaata taatcataaa agagaaatca gcaatgaact
     1861 aagtaaaaaa ttagaaatag agttctcgga tttataagtt taaatataaa aaataaaatt
     1921 ttaaaaaagt attgacaatt gatttagaag ggtttaaaat aaattacaac ataataaata
     1981 aaaaggcgat gaataggaag agtaaatcta attcgattac cagagagaag agtccgttgg
     2041 ctggaagact ttttaaatta gagggattga aaactaccta ggagctactt tctgaagtca
     2101 tctgcattag tagattttag taagaatagt cgttagctgc gttaaagtgt aaagtgagtt
     2161 ttcatgacat atgaaaacta aattaggtgg aaccgcggga ataatactct cgtccttatg
     2221 ttataaggat gagagttttt tgttatttaa aaatataaac agtaatcata ataattatag
     2281 aaaatataaa agcaatgaat aggaagagta aatttaattc gactatcaga gaggaaagtt
     2341 cacaggctga aagactttct aagtttgaga aattgaaaac tacctaggag ctgtggtctg
     2401 aagttacttt aaaaagtttt agtaagacta accgttaact gcgttaaagt gtaaagtgga
     2461 ttttatcaat aaatgataaa atcaaattgg gtggaaccgc gagtatagac tcgtcccttt
     2521 atatagggat gagtctattt ttattgcaat aaaagattga aaataaaaaa aaatcggaaa
     2581 attataaatt taggaggaaa ataaaatgga gaataaagtg aaaattggag tactaggata
     2641 tggagttgta ggaagtggac ttatagatat aatagataat aataaagaaa aaagaaatat
     2701 agaaatagtt ggaattttag ttaataattt ggaaaaacat aaggataaaa aatattctaa
     2761 tataataact aataatatag atgatatatt taataaagat atagatatac ttgttgaagt
     2821 catgggtggt ttagaaccat cattatctta tataaaaaaa gcattaaaca ataaaattca
     2881 tgttgttaca gcaaataaag atttgttagc tgaatgtgga gatgagcttg caaaattagc
     2941 aagtgaaaat aaagtaagta ttaaatttga agcttcagtt gcaggaggta taccagtatt
     3001 aaaaccaata atagaatcac tagaaggaaa taatatagat agtataaatg caattttaaa
     3061 tggaactact aattttatat tatctaaaat gtatgatgag aatctatctt atgatatggc
     3121 attaagacaa gctcaagaat taggttttgc tgaagcaaat ccagagtcag atgtattagg
     3181 gtatgatgct gctagaaaac tatcaatatt atcaactcta gcttatgaca atagagtata
     3241 ttggaaggat gtgtatttag aaggaattac agatatagat gaaaaagata ttgaatatgc
     3301 aaaaaaatta aattgtaaaa taaaattgat tggtcaaagt aagtatgaaa atgataaagt
     3361 aagtgctttt gttagacctg ttttagtaga aaaagataat atccttgcta gaatagacaa
     3421 tgagttcaat gctgtcatag tgaatggaga ttcagtagga gaagtttctt ttgtaggtaa
     3481 aggagctgga agtttagcaa caggaagtgc ggtttattca gatgttatag atataataga
     3541 taatagagtt tcaagtatag attcttttac taaagataaa atacaagtta ataaaatagt
     3601 tagagaaaag tgtggagcac ttcttagatt taaaaaatgt aataaagatg aaattctaaa
     3661 tatagttgag aattgtttag taaaattcga tattttaaat gatgatgatg aacttgctat
     3721 tatggtttat gctgattctg aatatgaaat aaacaacagt ttatgtctaa taaaagataa
     3781 aggatactgc gaaaaaatga ataaaatgtt gaaaataagt taaaaaagaa aaaatataag
     3841 tttatatgta acatattttg acgattttaa tactatatag tatgagatga aacaaaacat
     3901 ctcataaaaa aattaaaatt caagggagag atatgttata tggaaaataa aaaatatgca
     3961 aatggtggtt attcagaaga ctggtatgaa agaggagaat ctacagctaa atggttccag
     4021 aatgatagag aagaatatga aagagcagca tacgatgaag atagagaaag aagaggctca
     4081 aactgtggat gttcagattc aggagaaaat agacctagaa actgtgaaag atttagaaga
     4141 gaagcagaga taagagaaag agaagcaaga gaagcattct gtgaatcttc agagagaaag
     4201 aaagaagcac tagcatatga atgtgaagct agaaaattat gggaagaagc agaaaaatac
     4261 tgggatgaat attcaaaata caactataaa ggaatcgaat atttagcaga agctgctaga
     4321 ttatttgatg aaggtatgga atgtgaagct agaagaaatg gaaataatgg aggaaacaat
     4381 aataattgtt gccataaatg ccataaatgt aattgtaact gctgtagaaa ataaaaaaat
     4441 taattgacaa atcaatagtt aaaatatatc atattatgta taataaagag aaaattcaga
     4501 aaaaaataat gattagaaga aatataagta tatttattag acaaatagtg ctcagttagt
     4561 gaggtgagta caatatgatt aaactcccat cctctagctt ttgatagagg gtgggagttt
     4621 ttatttattt atatatctta aatgaggata atattgtaaa ataaatgagt atgagattgt
     4681 aaaattagga ggtaaaaaat gaagagtatt aaaacatcaa gtatgaaaga aaaggtagat
     4741 gaaaagatat taagagagca agtaagttct ataatagaag atataagaaa taataaggat
     4801 gttgcactta aaaaatataa tgagaagttt gatagaaata caagagatga atttagaatt
     4861 actaaggaag aaataaagga agcttataag catgtagatg acgaatttat aaataactta
     4921 aagattgctg ccaaaaatat aagagaattt gctaaagctc aaaaactaag ttttgaaaac
     4981 ccttttgaaa aagaaattta tccaggtgta atcttaggtc aaactaatat tccaatagag
     5041 tcatgtcttg catatgttcc aggaggtcag tatccattgt tttcaacagc tcttatgctt
     5101 ataatacctg caaaagtagc aggagtaaaa agaatagtgg catgttcacc aactatgaaa
     5161 aatactgaaa agataaatcc taagacattg gtagctatgg atatagcagg tgctgatgaa
     5221 atatatgcaa ctggaggagt tcaagctata gcagcattta catatggaac agaaaagatt
     5281 aatccagttg acataattgt aggaccagga aataagtttg taactgaagc taaaagacaa
     5341 tgttatggac aagtagggat tgattttgtc gctgggccaa gtgaagttct tataatagcg
     5401 gatgaaactt caaatccagt ttatattgca gctgatttat tagcacaatg tgagcatgat
     5461 ttaaatgcaa gaggaatatt attgacaaat agcttggaag tagcacaaaa agttgaaaaa
     5521 aatatagaaa gtatgctaaa agatttgcca acaaaggaca tagcatatag ttcatgggaa
     5581 aataatggag agataatatt ggttgatgat atggaagaag ccattaaaat aagtaatttt
     5641 tatgcaccag aacatttaga agttgcagta aatgagtata atgatatttg tgatagatta
     5701 actaactatg gttctttatt tattggaaat ctttctgctg aggtgtttgg tgactatgtt
     5761 tcaggtacca atcatacatt accaacactt aaagcatcaa gatatactgg tggtgtttgg
     5821 gttggaactt ttatcaaaac ttgtacaaag cagatattta atgaaaaagc tatacaatca
     5881 ttagcacctg tagctgaaaa gctggcaaaa gaagagggat tatatgcaca tgcaaaggct
     5941 gctgaggtta ggtttaaaaa gtagtaaaaa attttatttt ggcagtcgag atttagtgtt
     6001 agactgagat aaggaaaacg ctgagaaccc gaataaatac tatattttgt gggcctcggc
     6061 gtttctttta tatctgtata taataggata atactacctg tgtgtttaaa tgctagctta
     6121 atatttcttt tctaaataat gtttatgaaa tagttaatat ttttagttaa tacttgaaaa
     6181 aaacttttgc taactgtgca aattcatctg cattcgtcaa tatagcaggg tgtcctccct
     6241 gactaaaaat gtgaatactt gcttttgaaa taaaagttgc catttgtttg tactcttctt
     6301 caagattatg acgacacatt tcgtcttcct tacttcctgt aaataaaatt ggcatttcta
     6361 atttacacaa ttctttatga aacaaagggc gtttctcgtt tgcacattgc aatagagctt
     6421 ttgtatcaag attaacaaca ttctcccaat cttttccatg acaccattca tagaattttc
     6481 gtgcttgaat atcttgcttt gatttttccc ttccagtgat tagattatct atgaagttat
     6541 cattaagagt acgtccatca aagctatctg ctataattgc ttcaactaaa tcgggacgtt
     6601 ctaatccagt attaacagct gcccatgctc ctccacttgt tccaattaag ccaactttac
     6661 cacaattcaa atgttcaatc aatgctattg tctgtaaggc ttcatcatgc catatgtcag
     6721 gagaaaattg agaaactcta tccgactgtc cattacctaa aaaatcaatt aagatacatc
     6781 taaaattttc tacatataat ggcacaagtg ctttaaacat attagaagaa ccagtattac
     6841 catgcaggaa aattatcggt ttaccttgtc catattcttt ataaaaacaa gaattacctt
     6901 gatactgaaa atatgacata tattttcctc ctttttattt gttaagttaa ttataacaat
     6961 ataggtatga atgaaaaacc tcatgttctt tcttagaata aaaatgtgcc acgcataaaa
     7021 cgtgacacat ttctaattat aaattttgct gtttaagtat tctttgtatg cttttctctg
     7081 tcaaaaagta tttctctgat aactgcttga tactcattcc attttggaaa tttatacaga
     7141 tttgagaatt acgagaagct aagacttgtt tggtgtttgt gttttcaccc caatgctttt
     7201 tgtgctcttg ctttttggga atataaatca ctttaccatc tatatattct tgcacttgct
     7261 caatcagttc tttaggcagt aagtcaatcg aattttgata gctcattttg cacctcctaa
     7321 ataattattc tttaggatta gcaaaggcta ctgccactca caattaaaaa taaaattttt
     7381 tattatgtac aatagccttt gctatgcaca agttccaatt cccataaact aaatactcct
     7441 ttctggtttg aaaaattcat ctgaacattg atttcgcttt taagatagag ttcaatgaca
     7501 aatttacatt tttattatat atattcagat agataattgc aactgtcttt gtatgaggat
     7561 attttattat agtcaatact ataatatgta tttatatcat caaactaata tgaacagttg
     7621 aaaggaatat gaacaataaa acttagtcag gaagaataat tatgaagcag acaatagaga
     7681 aatttgattt taaagtttta ttgaaaattt attgacaaat ttaacttgta aatattatac
     7741 taaacttaat aaataaagtt tataaagtaa ggtgttgtct atgaaaaata tagttggaaa
     7801 accgcaaacg ataaaaaaag taaatgaaga tttaataaaa aatattataa aaaatgaagg
     7861 tcctataaca aaaccagaaa tttcaaacat tactgaattg agtttagcta cagttaataa
     7921 gattgtagag caattagctt tgaaaaatga agttaaagta agtggactaa gtgaatctac
     7981 tggaggaaga agagctcaat tatttgaaat aaatgcaaac ttagaacaca taatagcttt
     8041 atattattat agaaattgtt gtataggggt agttgccaat ttattaggtg aaataattta
     8101 tcaagaagaa tttaatataa gaatggatac gtatgaaaac gttaaccaag atactttttt
     8161 tgttatagat actctaataa aaaaggaaaa aggaaacaat ataagggcta ttggaattgg
     8221 tgtcccagga gttgtaaaaa aaggtgtagt taaaaatata ccaactataa aaagttggga
     8281 aggtataaat ttagaaaatt taataaagag taaatacaat actaaagtgt ttatagaaaa
     8341 tgatacaaat attactacta ttgggattta tcaaaaacag tataaagaca aatataaaaa
     8401 tatggctctt atgtatttag aagatggtat tggttcaggt atagttataa atggtgaatt
     8461 gtatttaggt tctacaaatt ttgctggaga gttaagttat ctaaatatag aatttggtaa
     8521 gtataactct aacaacttaa atcttgaaga ttatattatg agtttaagaa aaagatattt
     8581 agaaagtaaa gataataaat ttaagaaaga aattttatct ataatatcaa actttataag
     8641 gactcttgta tgtgtcctaa atccacaagc tatgattata cagtgtagta tattaaccaa
     8701 gagtgacatg gagtttatag aaaaagatgt aagcaataat gttggagaag aaaattttcc
     8761 taaattaata aaagtagact cattgagaga aggaagtata aatggagtaa ttagtatgtg
     8821 tttaaaagaa actgactatc aatattcctt atctaataaa aaaggaggat attaatgtga
     8881 aatatttggt ttcaatagat ggagggggaa caaaaactaa attttgtgta agtgacttag
     8941 atggaaacat acttaaagaa cataccactg gttcaactaa ttataagtca gttggaatta
     9001 aaaaaacata tgaaaatatt aataatggat ttaaaaaaat attaaaagat ttatatatcg
     9061 attatgacga tattgagtac actgtatttg gtatatctgg ttgtgattct cctaatgatt
     9121 ataagattat aatggatgaa atattaaaaa ttgggattaa caaagaaaaa atatatctgg
     9181 caaatgatgc agttttagct ttttatgcac aagctgattc ccctggttta gtaattgtgg
     9241 ctgggacagg ttcaattata ctgggaatta aagaagatgg agaaatatat agagttggtg
     9301 gatgggggta taattttagt gatttgggtt ctggatatga tatagggaga aaattattaa
     9361 agaaagtatt gctttattgt gatgaatgtc atgagtatag tgatttattt agttgtgtct
     9421 tggatttctt tggagcgaat agttttgaac aacttgcata tatgattact gatataaacg
     9481 ataatgttga aatagcaaac ctagcttcat tagtgattga ttgtgccgaa caaggtgata
     9541 aattggctat tgaaatatta agagaatcat caactgaact atctaaatta gctcaagtaa
     9601 tattgataaa aatatctaat ccaatgaaaa tggataaaag cgaaataaat atagttttgt
     9661 ctggtggtac attaaataaa actgtatatg ctcaaatgtt aatgaataat ttaaaaacag
     9721 aaaatacaga taaaaattta aaatttatat ctcaagaaaa tcagccagta tatgggggga
     9781 taagacttgc tatggcatta gctaatagga gggtcaagca tggatagaaa aaaggtaata
     9841 gtacaaattt ttactggagg ttttaaggct aaagaaataa agtttaatga tataaaatgt
     9901 aaactactag aattattgaa ctgtattgat atagaaaagg ttatcatggg atggagtgta
     9961 gatgaagaat tatatgtaga aactaaaaaa ctattaaata aatataatgt tgaactatat
    10021 ctttggttgc catgtttttc tgaaatagga ttacttgaaa aaagtaattt gctaattgat
    10081 tatatgggga aagaagtcaa gggctatgct ttacaagagg atgaaaattt tgagttttat
    10141 tgcccaaata ataaggaaaa tataaaaaat ataaagaaaa tatatagtac ttattttagt
    10201 gatattaaat ttgatggaat ttttttagat aaaataaggt atggttcttt ttcgaataaa
    10261 ctaaatggtg tttttaattg tttttgtaaa gattgtttaa atatatatga aaaaaataat
    10321 attgataaag agtcgttaat gagagaaatg aataatgtgt ctaagggagt tatagataat
    10381 gaagatactc catttggtat aacagaatac attaatggaa aatacaaatt taaaaataaa
    10441 atatgggaag atttttttga aacaaaaaat caaaatatat acaaggcatt attagagata
    10501 agtaattatt ttaaaagtaa gggattgaaa ataggtatag atactttttc tccttttatt
    10561 tcttacttta caggtcaaga tttagaaaaa ttacaagaag tagcagattt tataaaacca
    10621 atgatgtata gaactacaaa agctccagct ggtttaccat ttgaatttga aaggtttatt
    10681 gatgaatcca tacataagaa taaagagatt ggaaaaagaa atttcttaga tattttagga
    10741 attaaggagt atgaaggaaa tgtataccct atagaatttg tactagagga aatcgatttt
    10801 atgacaagaa atcttaataa agatatatat gtaggagttg aaataaataa aaaggaaatt
    10861 atagctcctg ttacacctaa gtacataagt gaaaatattt caaatataaa taagacaaca
    10921 gtaaaaggat atgttttatc ttgggatttg ttatcagcac caaaagaaaa tattgatgaa
    10981 attataaaat ggtttcggaa ttagtgaggt gatatagtga gtaagatatt ggaaatgcaa
    11041 caaatatata aaagttttgg aaaggtagat gttttaaaag ggataaattt tgagttagaa
    11101 aagggagaag taagagctct tttgggagct aatggagcag gaaaatctac acttattaaa
    11161 attttaggag gagttcattc ccaaactaaa ggtaaagtaa ttttgactgg taatgaaata
    11221 atgtttaaaa atccacatca ttctaaagaa aatggtatta gtataattta tcaagaatta
    11281 agcttgatac caacgcttac agtacttgaa aatatttttc ttggtagaga aattttaaaa
    11341 ggaagtgtgt ttttaaacaa gaaagacatg cttgaggaat atatgaaaat ttgtgaggat
    11401 tttgatttta atatagaccc acatatagta gtttctaatt taagtgtagc aaaccaacaa
    11461 atggttgaga taatgaaagc tgtttcatgt aattctgaaa ttatcataat ggatgaacct
    11521 acaacatcac ttactaataa tgaaaaagat gggctattta aaataataag tagactaaag
    11581 tctaaaggta aaacaatagt ctatatttct cacatattag aggaagtttt taaagtatgt
    11641 gatagtgcaa gtataatgaa aaatggaatt atgattggaa cttatgatgt agaggattta
    11701 actaaattaa agataactca acttatgaca ggaaatgata atcacaaact tattgagaag
    11761 aaggattata catttgcaaa atatgaagag ccaccagtac tagaagtaaa gaatataagc
    11821 tggtctaaca aaataaaaaa tgtttcattt aaagtttata gaggcgaagt tgtaggtctt
    11881 gcaggtcttg taggttcaag aagaactgaa attataaatt tgatatttgg tatagataat
    11941 aaagatagtg gagacatttt tatcaatggt aaaaaagtag acataacttc tcctaaggtt
    12001 gctataaaaa acaaaatagg attgattcct gaagatagaa aaaatctagg attaatttta
    12061 gaacaagcta tatacacaaa ctcatcatca gtacaaattg ataaattcaa gaaattcttg
    12121 tttatagata gaaataaaga aattgagttt tctaaaaaag gtgttaagga attaggaata
    12181 aaagttagtg atgtaaagca agaagtaaaa gagcttagtg gtggaaatca acaaaaagta
    12241 gtagtttcta agtggttaga gaaagattta gatttaataa tatatgatga gccgacaaag
    12301 ggaatagata ttgctgcaaa agaagatatt ttcaatacaa tcaaagaatt ttcaagtaaa
    12361 ggaataggag taatatttat atcttctgat ttagaagaag taataagagt aagtgataga
    12421 attttagtaa ctagagaagg ttctattgta gatgatttaa aaaatgagaa tatacaggtt
    12481 caagatataa tgaacagtat atttaatgta taaaaaatga aaatggagga ctgagatgaa
    12541 gaaagctttt gagaagttaa atttaagaga ttatggagta ttattaggtt ttttagcttt
    12601 atgtatagct ataagtattg caactccatc atttttaggt aaacaaaata tacttaatct
    12661 tttacgacaa tcttctataa ttggaataat ttcagcaggt atgacttttg ttataatatc
    12721 tggaaacttt gatatatcag ttggagcagt agcagctctt gcaggtgcta taacaatgaa
    12781 atttgcgact ggtggaacta atttgtttgc atccatgttc ttaggtgtag cgatttgtgc
    12841 agtaatagga ttaatcaatg gtatagtagt tgcaaagata aatgtaccat cattaatagc
    12901 cactatggct atggtcacta ttgtaagagg attgctgttg atgcttacag gaggatatcc
    12961 aattactgaa aatataccaa tacttgatta cattggaaat ggatatttgt ttaatatacc
    13021 aataccagta gtaattttct ttatagtggt gttagcttcg tttattgtac ttaataaaac
    13081 taagtttggt agatatgttt attctgtagg agggaatcaa gaagcaagta aacttaatgg
    13141 tataaatgta gattctcaca aagtgaaagt gtttattatt aatgctgtac ttgcaggaat
    13201 agctggaatc gtactaacag gaagacttgg gactgcaact gcgattgcag gtgaaggata
    13261 tgatatggat gcaattgcat ctgtagtaat aggaggtaca tcagtggcag gaggttctgg
    13321 ttctgtactt aaaactgtta taggagtatt acttatgagt gttataaaca acagttttaa
    13381 tcttcttgga atagatgtat atttccagta catatttaaa ggattaataa ttttagcagc
    13441 agttggattt gattcttata gcaagaaaaa acttgcttca agataaaaaa taagggggat
    13501 ttttttatga aaaaattaat gaaacattta gcattgttgc tatcacttgt tatgatattt
    13561 ggtttagttg gttgttcaaa tggtggtgac aaagaaaaaa atggagaaaa gaaaatagca
    13621 gtattactac caggttcaac aggttacttt gtagcaacta aacaaggtat agatgcaaaa
    13681 tctaaagaat taggtgtaag cgtggaatat gcagatgctc aatgggatgc tagtaaacaa
    13741 ttatcacaag ctgaagattt tatggctaaa ggggtagaca tgattgcatt atgtggagtt
    13801 gattctgctg taagtgagag aatagttaaa gctgctaatg attcagacgt tcctatagta
    13861 gcatttacaa attctatagg aagtaaccca actggagaat ttaaaggttt agttacatat
    13921 ataggacaaa atgaggaaga aacaggagca ttaactggaa aaattgctaa aaacttatta
    13981 ggagaaactg gtgggaaagc tgtattaata gaaggagtac caggaactac tccacaagta
    14041 ttaagaaaaa aaggtcttga aaaagaatta aaagatagta atatagaaat agtttataat
    14101 caaacttcaa attgggagaa agagcaagct ttaaaggtaa cagaagattt aattcaaaag
    14161 aaaactgatt ttaatgttat aatatgtcaa gatgataatt ctgctacagg tgcaggtcaa
    14221 gctttaaaag atgctggtct taaggataaa gttaaagtca taggtttggg tggaagtaaa
    14281 gatggattaa aagctataac tgatgggtta atagatggta caacttatat gtctgctgta
    14341 gaagaaggtg gattagtcat agaaaaggca tctaaattcc ttaaaggtga aaaaatagaa
    14401 cctgttacac aaattaaaca agttgaagtt aacaaagata atatttcaga gttcaagggt
    14461 gaatggtaaa ttgtcataga taataaataa gatttttaga gttactttag aaactatata
    14521 aagtaactct ttttttaatt taatttagtg ataaattatt gaatagtatt tctaaacaaa
    14581 taaaaaatta atataaacaa agacttaatt atactaaatt ataagtaaaa ctaatataaa
    14641 cttatggaaa aaaggaaaac gtctaaagca ttggaattac tatagtgtag gtgtggtatt
    14701 aaaaaaacat aaaaaaacat aaaaaaattg ttgaaaaaaa tatagaaatt ttgtataatt
    14761 aaagatttga aaagtgcggt atacaaagcc aattcttttg tatataatat atataaattc
    14821 agaaaaagga agggatatgt atggccaggc ggttattttt agaaaggatt ggacttatat
    14881 ttttaggttc agcaatatta gcatttggag tttataattt ttattattta aacaacataa
    14941 cagaaggtgg agtgttaggt attttactac tgttaaaaaa tttattcaat atacaaccag
    15001 caatagcaaa tgttgtaata gatggtttac tacttttagt aggatataaa tttttcggta
    15061 aaaaattcct tatatattca atagtagctt ctataacttt ttcagtgtta tatgacttat
    15121 ttgaagctat aggacctcta gtaccacaat cacaaaatat gcttttatca actattttgg
    15181 caggtgtaac tgttggaact ggtgtaggta tagtagtaaa agcaggttgt gcatcaggag
    15241 gagacgatgc tttagcatta gtaatttcta agactacatc tttgaacata gggcaagttt
    15301 atttagcaac agatgttatt gtattgttgt tatcattatt ttatctatca gcgtttgata
    15361 tcttttattc tttgattgct gttacaatta gtggcaaggt aattgatttt atttattatc
    15421 atggtaaaag tttggatatg gatataagta atgatatagt tccagaatgt taatataaat
    15481 taaataactt tagattttat taggggtggc agatttgcca ccttttttgt gtctaaatct
    15541 ttatagaaag tataatccca tctaggtttt tgcaaatctc aaatatagaa ttatgttgga
    15601 atgactggga atacgattgc cagatgtgca ttttaaaaac ccaattttat atttatgaaa
    15661 tactaatcat taatggatgt ttcttaatcc tatctttata cctaaaatga taagataaat
    15721 gaagtagcaa tacaaagcta aaatttgtaa aagagattaa attaaatgga ggagctaaaa
    15781 tgttggatat agttatgata gcattgttat tcataggatt tgtttccatg aagttacttg
    15841 ctgattggtg tgggaaacaa actgaaaaaa aataatgtaa tgtatggagg gattacctat
    15901 gtggtttctg gcagttgtaa ttataatgtt aataatatat ttggtatatg cgcttattaa
    15961 tcctgaaaaa ttttaaacag tataaggcta ataagtaagt tgaattgggg ggaacaattt
    16021 ttatggtgca gatagtaata gtgttagcga tttttatgat tttagtaata cctatgggca
    16081 agtatttata tcatatagct actaatcaaa aaacatttgg agatagacta tttgataaag
    16141 tggacaattt tatatataag gtatgtagta tagataagaa aaaagaaatg aactggaaac
    16201 agtatgcatt agctttatta tttacaaatg cagttatggt atttatagga tatatcatac
    16261 ttaggactca aagtattcat atttttaatc caagtggaat taaaagtatg gaacaaggac
    16321 tatcatttaa tacaataata agttttatga caaatacaaa tcttcaacat tattcaggtg
    16381 aatcaggact ttcatacttt agtcagatga cagtgataat atatatgatg tttacatcag
    16441 ctgcaacagg atatgcggct gctatggcat ttgtaagagg tctagtcggt aaaaagaaaa
    16501 cattgggaaa tttttatgta gatttaatta ggataacaac aagagtactt ttaccaggag
    16561 ctttaattat tgggcttata ttagttacac aaggagtacc acaaactttt gctgggacag
    16621 aaacagtgac tactatagaa ggaaagcttc aagatatagc tagaggtcct gtggcagctc
    16681 ttgaatcaat aaaacattta ggaacaaatg gtggtggatt ctttggttca aattcatcac
    16741 acccatttga aaatccaaca ataatatcaa atatagtaga aatattatct atgatgatat
    16801 taccaggagc ttgtgttgtt gcatttggtc acatgataaa gaataaaaaa caaggttggg
    16861 ttgtgtttgg cgcaatgtca atcatatttt taataggtct agtagtgtgc tttaaagcag
    16921 aaagtgcagg aaatcctatt ttatcacaat tagggcttaa tcaaagtatg ggaagtatgg
    16981 aaggtaagga agttagattt ggtatagcac aatcatcatt attcacaaca gtgactactt
    17041 cctttacgac aggtacagtt aataatatgc atgatacact gactccttta ggaggattag
    17101 taccactttt aaatatgatg ctaaatgtag tatttggtgg taaaggcgta ggtctgatga
    17161 atatgttgat gtacgctata atagcagtat tcttatgtgg attaatggta ggaagaacac
    17221 cagagttttt aactaagaaa atcgaaggaa aagaaatgaa gcttattgct ttacttatta
    17281 tattacatcc acttttaata ctaatgttct ctggtctttc agtagcaata ccagcagggc
    17341 ttgaaggaat ttcaaatcct ggattccatg gattatcaca ggtattgtat gagtttgcat
    17401 cttcagcagc caataatggt tcaggatttg aaggtctagg agataacact atgttttgga
    17461 atataacaac aggtatagtt atgttctttg gaagatatgt gtctattata gtactactag
    17521 caatatcaag tttgttagca tctaaaaaag ctgtaaatga aagtatagga acacttagaa
    17581 cggataattt tacatttaca atagttttag tacttgttgt tttaattgtt ggtgctttaa
    17641 catttttccc agccttagcg cttggaccta tttcggagca tctagtgttg tggcactaaa
    17701 aaattgggag ggagtaaagt tttatggaaa ctaaaaaaac aaagtttatt acaaaagata
    17761 ttttcaaaac ttccattata gaagctttta aaaaattaaa tcctaaatat atgatgaaaa
    17821 atccagttat gtttgttgta gaaattggat ttatagtaac attgatactt acaatagtac
    17881 ctagtttgtt tggtgatgaa ggcaataact taagagctta taatgggatt gtaacaataa
    17941 tcttatttat aacagtcctt tttgcaaatt ttgctgaagc tgtagctgaa ggaagaggta
    18001 aagctcaagc agatacactt aagaaaacta gaaaagatac agtagcaagg gttatagata
    18061 cattaggaaa tgaaaaaatg ataagtgcaa gtgagctaaa acttggtgat attgttttag
    18121 taaatgctgg agaggttatc ccaaatgatg gagaagttat agagggtata gcttctgtgg
    18181 atgagtcagc aataactgga gaatctgcac ctgtcatgag agaatcaggt ggagatttcg
    18241 catctgttac aggtggtact acagttgtaa gtgactggtt aaagataaga ataacaacaa
    18301 aaccaggaga atcgttctta gataaaatga tagctcttgt agaaggtgct tcaagacaaa
    18361 aaacgccaaa tgagattgct ttaaatactt tgttagtagg gttaacactt atatttatgg
    18421 ttgttttaat atctctttat ccaatggcaa actatgcagg tgtaaagatt ccaatttcta
    18481 ctatgatagc tcttttggta tgtttaatac caactactat aggtggattg ttgtcagcta
    18541 ttggtattgc aggtatggat agagtaacta gatttaatgt aattgcaatg tcaggaaaag
    18601 cagtagaagc ttgtggagac gttgatacta tgattttgga taagacaggt acgattactt
    18661 atgggaatag acttgcatca gaatttatag cagttggaaa tgcagattca aaagatttaa
    18721 taaattattc tgttatgtgt tcattaaaag atgatacacc agaaggaaaa tctatagttg
    18781 atttaggtat gaaattaggt tcaacaggta agacaaaaga ggcagaggaa gctgagtttg
    18841 tagaattttc tgcacaaact agaatgagtg gtattaactt agctgatggt agagctataa
    18901 gaaaaggtgc ttatgatagc ataataaaaa gagtaaaaga atctggtggt acagtgccag
    18961 aagatttaga agaaaatgta aatcgagtag ctaaactagg agggacacct ttagtagtgt
    19021 gtgtagataa tgagatatat ggaattatct acttaaaaga tacagtaaaa tcagggcttg
    19081 tagaaagatt tgctagactt cgagagatag gaataaagac aataatgtgt acaggggata
    19141 atcccttgac agcagctaca attgcaagag aagctggagt agatggattt attgcagaat
    19201 gtaaaccaga agataaaata gatgcaataa aaaaagaaca attagagggt aaaatagttg
    19261 caatgacagg tgatggaaca aatgatgctc ctgcacttgc tcaggcagat gtaggtcttg
    19321 caatgaatag tggtacaaca tctgcaaaag aagcagcaaa tatggtggat ttagattcag
    19381 acccaactaa gatattggaa gttgttgaaa taggaaaaca gcttttaata actcgtgggg
    19441 ctttgacaac atttagtata gcaaatgatg ttgcaaaata ttttgcgatt ataccagcta
    19501 tatttactct tgcaatacct caaatggaga tattaaatgt aatgaaactt tctacgtcat
    19561 ttagtgcgat attatcagct ttaatattta atgctataat tatcccatgt ttaatacctc
    19621 ttgcaatgaa gggagtaaaa tatagaccta tgaaatcaca agctatgtta atgagaaata
    19681 tgcttatatt tggtcttggt ggagttatag taccattttt aggaataaaa ttaattgatt
    19741 tattgattac acctttagta atggttctta atttaggtta ataaatggag gatataaaaa
    19801 tgaaaacatt aaagccagca ttacttgtaa gtattgtatt gttagttgtt tgtggacttg
    19861 tatatccact tgttttgaca ggtgtaagtc aagttgcatt taaagataaa gctaatggaa
    19921 gtatgataga agtaaatggt gtaaaagtag gttcagaact tattggtcaa agttttacag
    19981 atgcgagatt ctttaaggga agagtatcat cagtaaacta taatacttat acaaaagaag
    20041 atttagtacc agataaagat ggaaatacat cttatggagg tgtatcatca gggtctttta
    20101 attatggagc tacaaatcca gagcttcatg atagagtaca aaaagatata gaaaagtttt
    20161 taaaggataa tccaactgtc aaaagagagg atataccaac agatttactt acagcatcag
    20221 gttcaggact tgaccctaat ataagtccag cctctgcaaa aattcagata ccagctatag
    20281 caaaagcgtc tggaatatca gaaagtaaat tacaaaaaat tgtagatgat aatacttcca
    20341 aaaaactttt tggagtttta ggtgaagata gagttaatgt actaaaggtt aatgtagagg
    20401 tcgcaaaaat attaggtctt atatagtatt ttgtagaatt ttagtaacaa aatattatgc
    20461 aagatttaat ttaaaggtta aattttaaag agtgaaaatc aataatgatt ttcacttttt
    20521 tatttgaata ttactaatat ttggaataaa gtgattgtaa gtataaaatc caaaaaaagg
    20581 ttgcattatc aaaatgataa tactataata tatttatcgt tatcaatttg ataatagatt
    20641 tggacatata ggaggaaata gtatgttata taataacgca ttagagttga taggaaacac
    20701 acctgtagta aggctgaata atttaggctg tactaatggg tgttctaaca tatatgtaaa
    20761 attagaaaaa gtaaatccag caggaagtat aaaagataga gctgtttatg aaatgttaga
    20821 gggtttagag caaagaggag aattaaaaaa gggagatgta ctagttgaag caactagtgg
    20881 aaatactggt attgcattat ctatgatagg aaaattaaaa ggatatgaag tagtaatcgt
    20941 aatgcccgaa acaatgagcg ttgagagaag agatttaatg aaggcttatg gagcaaattt
    21001 ggtgcttaca gatggtaaag ctggaatggc aggttccata gaaaaagcaa atgaactttt
    21061 aaaagaaaat ccaaactata aaagcttaaa acaatttgaa aataaagata atccaaatgc
    21121 acattataaa acaacagcag ttgaaattat gaatgatgtc aaagatttag atatattcgt
    21181 atgtggagtt ggaacaggtg gtactttaat aggaactgca agatatttaa aagaacaaaa
    21241 tccaaatata agagtaattg cacttgaacc aaaaaaatct ccagctatat cagaaaacaa
    21301 gactggacct cataaaatac aaggaatagg tgctaacttt gttcctgaaa attatgattc
    21361 tagtgtagtt gatgaagtaa tattagtaga tgatgaagat gcatttgata cagttaaatt
    21421 acttgcagca aaagagggaa ttttagtagg gatatcttct ggagcaaata tatttggtgc
    21481 tatagagatg gcaaaaaagt atccagataa aaagatagtt acagtagctc cagatggagt
    21541 tgataagtat atgtctatgg gaatatttta ataattttat ttgagggagt gaatactttg
    21601 tttaagaaaa taaataaaga tattgaatat ataatgaaga atgatccagc agctaggtct
    21661 aagatagaag tttttttact ttatccatca gttcatgcaa tgataatgca taggatggct
    21721 catgctcttt ataagaagaa gaagcttttt acagcaagat taatatccca gatatccaga
    21781 tttatgactg gcatagaaat acatcctggt gctaaaatgg gggaaggtat attgatagac
    21841 catggaatgg gtgttgtaat tggagagaca gctgaagtag gtaatagggt gacaatatat
    21901 caaggagcta ctttaggagc tacaggaaaa gatactggaa agagacatcc aactgttggt
    21961 gatgatgtat taattggtgc tggaacaaaa atactaggac ctttaaatat aggttcaaat
    22021 tcaaaaattg gtgcaaattc tgttgtcgtt aaggatgtac ctaatggtgc aacagttgtt
    22081 ggtataccag caaaaatagt aaaaataaga aacctagaac ctgtaaaaaa gaataaaaaa
    22141 gaagtgtcct atgagtatga tgaattagat aatgtatatt atatatagga tttatataac
    22201 tataaaataa actttataaa aattatttta aaaggtattt ttttcaaatt tgaggacata
    22261 ataaaaaaga actgaatgtt acagttttgg ttcatcaatc tttgataaac aagattttaa
    22321 atttgtagcg tctaggagga ttttattatg aaagcaaatg ttaatcaaga tacttgtata
    22381 ggttgtggat tatgtccatc aatatgtcca gaagtatttg atatgaagga tgatgggaaa
    22441 tcacatgtta tagttgatga agtaccaagt gatgctgaag aatcagcagc agaagctaga
    22501 gaaagctgtc cagttgatgc aatagatgtg cattaataaa ataaatgcct ataaaaattg
    22561 aattttcaat ttttataggc atttgtcttt tattcagtta gtatttcaac acctgtttct
    22621 gtaactaaaa ccatacattc ccattgagca gataatttac catcttttgt ataaatagtc
    22681 caattatttt cttcatcaac aaaaatttcg tgagttcctt catttaccat aggttctatt
    22741 gtgaatatca tcccaggaac caatagcatc tcagtccctt ttttagatac ataacttaca
    22801 aaagggtctt catgaaagct taatccaact ccatgaccac ctatttctct aacaacagag
    22861 tatccatttt tctttgcata agagttgata acatcaccta tatctcctaa gaatccccat
    22921 ggtttggcaa cttcaagacc tttttggaca cattcctttg taacttgaac taattttttt
    22981 gcattttcgt taacattacc tatcataaac attcttgaag catctgaata gtatccgtta
    23041 aaaatagtag aaacatctac atttataata tctccatctt ttaagataat gtctttactt
    23101 ggaataccat gacaaacttc attatttact gatgtacata cacttttagg aaatccatta
    23161 tagtctagtg gagcagggat agctccattt tgtagtgtaa agtcatgaac caacttattt
    23221 atatcttctg tagacattcc aatttcgatt ttatctgaaa tataatccaa aatttttgtg
    23281 tttattacag cacttttttt tatttcctca atttgacttt cattttttat aatatcatga
    23341 gttggtacaa tatgacctaa cttagcaaat gaatctattt tattatccat atccatatga
    23401 cattttttat attttttagt acttccacac caacagctat catttctatt taacttcata
    23461 acttttcatc cttcttttat tatttattta aattatgggt tacataaact attttaaaac
    23521 ataaccatta taaatattat aacataaata ctaagaaatc ctttatagat agtgatttat
    23581 tcaaagtata aattattata tggttattgt tgatgaaaag aggatagtta aatgtattat
    23641 tggatattag cgcacttaat agtttagttc aagtttttca agaaaatcat atgttagagg
    23701 acaattttcc tttaaagtat tttttgaatc ttcatcaaga taataatgta caaatgattc
    23761 tgcaaaaaat tcttctataa acttgcttat atatgcatgt gcaacttgct tagggtcata
    23821 aagcttatat ctttcctgag caaatacttc cataaattct tcagaatttg attttttatt
    23881 taaaacattt ttatctatag catgtgcagt ttcatgtaat tctaaatttt ttgatgaatg
    23941 tacatttgca tagctagggt tactataacc tattttagcc actatagaat tatttctata
    24001 tataccaggt acatctttcc aagtcttgcc tgatcttacc caacatggag gtaattgata
    24061 ttttaaatca ctaaattctg gttcatcagt tagatttgaa tttattaatt ttatttttat
    24121 atccttttct ttaagtgtct gtaaatattt aatatttatt tttgcaagtc tgtttttcat
    24181 attttcaact tcatctttat cataattcaa gtcatcagga agtataagca tttgttcaat
    24241 tatatctata ctactgtctt ttatattttc agattcttca tcaaatttat attgaagagt
    24301 attattttca tagatagtta tatttgtatt attttctata gaataagagt gaatatcctc
    24361 taaatctaaa atattcattt gttgtaaaat atgttttgtt tcgccactcc acactactaa
    24421 agaaagtgaa ttaaaattaa ttagtggatt ttcttttgct tttatatcat tgcttatatc
    24481 tacatcaaat acatattcaa ttgagtcttc tatgttaaga ctatctgtat tctttttaat
    24541 atataaatac gcttgtttta agtctatata aatctcatct aaagattcgt cataaaattc
    24601 tgataaatta ttagtaaaga gttcttcact taaaagttca tttttatcag ttatactttc
    24661 aattaaaata ttaatttctt ttatcatatc gtaaatactt atttttctat ttgctttttc
    24721 actagataca ttgcatggcg caagagcaat gcaataaaaa tctttttctt ttttataaaa
    24781 ggctttaagt gattttgata aaagtgtaaa gtctacacct atctgtaagt tgaccttaag
    24841 tgagtcattt tgtaataatt cagtattatt tcttttagct gtatttaaat tgttttccat
    24901 aatcattgcc ccctttttat tagggtatca taattttttt atatgtgtca atttgttttt
    24961 ttgaaaatta taattttttt gaaaatttta ttttttataa tttgtgaatt ttttattata
    25021 gaaataaata tgttattatt atgtcaaaat ttagcattag attcatgtag agtatgtttt
    25081 atacatatat tataattaat tctttgaaga ttgcatattc aaaatacaca ccattttttt
    25141 taattctata atataatatt tatatattta atgttaggat gtgatttaag gtgtatttta
    25201 catatattat aagatgtaaa gatgattctc tatacactgg atataccagt aatatagtta
    25261 gaagaatgaa tgaacataaa ttaggaatta attcaaaata cacaagagca aagggatttg
    25321 aaaaactaga agtttatttt gtgaccaaca caaaaagcaa tgctatgaag ttagaatatt
    25381 atataaaaaa attaactaga aataaaaaat tgtctataat aaaaaaccca agtatactta
    25441 taaatttaat tgataataaa gaagattata ttattggtaa ggaaatagaa caattaacat
    25501 aaatatttat agtaacatta taatgggtgc atatggtgta aaaacttgac aataaatact
    25561 attgtaatat aatgaagtta taaatatagt aaattaaaat agctagggga gccaagagct
    25621 gagaggtata ccgaccctta cacctgatct ggataatacc agcgtaggaa agcttagtaa
    25681 aaattcaagt atgtattatt tgtgatatat gctatttcta agctatacct attgtaggta
    25741 tagctttttt aattaagtta tttaaattaa actttaggag gcaacaatga gtaattataa
    25801 aataccaaca cttacaatag ccggctctga ttcatctgga ggagctggga ttcaggctga
    25861 tttgaaaacg tttagtgcaa ttggtactta tggtatgagt gtaataacag ctataacagc
    25921 acagaatact aaaggagttt ttgctgtaga ggatttaaat aagaaaataa taaaaaaaca
    25981 aatagaggca gtctttgaag atatacctcc aagagctgta aaaataggaa tggtttcaag
    26041 tcctgagatt atacttgaaa tagttgagaa tctaaagaaa tacaatccaa aatatttggt
    26101 tgtggaccca gtaatgatat ctaaaagtgg atattatcta ttaaagccag aggcaaaaga
    26161 aaacttaatt aagtatttga taccacttgc atacataatt acaccaaata taccagaggc
    26221 agaagaaata acaggaataa aaatacataa tgtagatgat atgaagagag taggagaaga
    26281 aatactacaa cttggaccta aatttgtact tatgaaaggg ggtcatttag atggagaagc
    26341 agtggatatt ttagttggta aaaatatatt taaagtttat aaaagtgaaa gaattgataa
    26401 aaaaaataca catggaacag ggtgcacatt atcttctgca ataacatctt atctagcatt
    26461 aggatatgaa ataacagaag cagtaaatct aagtaaaatc tatataacag aagcaataaa
    26521 aagaagtttt gatataggtc atggagtagg accagtacat catttttata aatttgagta
    26581 ataaaaaaat attggaggta gaatatgtat aatttaatta aagatgtaaa aaaattaaat
    26641 ccattggtaa ttcattatac taataatgta actataaatg attgtgctaa tgtaacttta
    26701 gctgtaggag caagtcctct tatgagtttt tcatatgagg aagtagaaga aatggtaagt
    26761 gtagcaaact ctgtagtaat aaatatagga actatgaact caaatatgtt ggatttattc
    26821 ctattagctg gaaaagcagc aaataagtac aataaacctg ttgttttgga cccagttgga
    26881 gtatttgcaa gcaaagcgag agcagaactt acaagtagac ttttaaatga agtcaaattt
    26941 agtgttgtta aagggaatgt atcagaaata aagtttatag gtggctttaa tgtaaggggt
    27001 aaaggtgtag attcatttga tgaagaagaa gattctactg agataataag aaagattgct
    27061 gaaaagcttg aatgtgtagt tgtagcaact ggaaaaatag atataataac taatggtaaa
    27121 ggtacatata aaataaacaa tggaactgat aaattaaaag gaattacagg aactggatgt
    27181 atgactgcta gcttgattgc aagttttatg gctgttactg agaatatatt agaagcagca
    27241 acaatgggtg ttcttacaat gtctttaagt ggggaattag ctaatttaaa taatccacca
    27301 ataggtacat ttaaagaaaa tcttatgaat gctatttatc aaatggatat agatacttta
    27361 agtaaaaatt ctaatattga atttttaaat taataaagag taagggagac ttaaaatgat
    27421 tgataaagaa tctttaaaaa aatgtttaaa gttgtattta gtaactgact ctgaaatgct
    27481 taaaggtaga gacttttata aatgtcttga agatgcaata tcttctggaa taacaactgt
    27541 acaacttaga gaaaaaaatg cttctggaag agagttttta agaaaagcta tgaaacttag
    27601 agaaataact aaacgatatg gtgttaagtt tataataaat gatagagtgg atatagcact
    27661 tatttgtgat gcagatggag tacatgtagg acagagtgac attgatgtta gagaggttag
    27721 aaagcttata ggaaacaata aaattctagg agtatcagca agaactttag aagaagctat
    27781 ttgtgcaaaa aatgatggcg cagactattt aggtgtaggg tctatattca caacatctac
    27841 taaattagat gcaaaatcag cttcgtttga aactgttaaa gaaattaaag aaaaagtaga
    27901 catgtcattt gtactaattg gaggtataaa tttagacaat atagataaac ttaaatgttt
    27961 agaaagtgac gggtatgcta taatatcagc tatattaaaa gctgaagata tctctaaaga
    28021 agtggaaaag tggacattaa aaatataaaa ttggctctgg tagtgaaaaa aatggaaaaa
    28081 tttgatataa tctaagagta aaatttaagc aattataaat gataaacttt tctacatata
    28141 ctttttaatc aagatatatg tagatttggt taaaaaggag ctataaatga ttaggatatt
    28201 gttagtgtgt gttggaggca tgtcttctac cctattggta aataaaatgg agaaggatgc
    28261 aaaaaaaaga aatatagact gtaaaatatg ggcagttgga gaaggagata taaaatcgga
    28321 gcttgataac tttgatattt tacttcttgg accacaactt agatttatgc ttgatgacgt
    28381 aaagtctata gttggagata gagctccagt atctataata gatatggtaa actatggcac
    28441 ttgtaatggt catgctgtgt taaattcggt tttagaaata ttaaaataaa taataaaagt
    28501 ggattctata taatagagtc catttttatt atttgttatt aataggctta aaacttagct
    28561 taccatttct ttttttaatc tccacatagc aagtgaaaaa cttgaacagc acaatattaa
    28621 aaatagtagg ataacaggca gtatatctcc aataagaata gtctcaccaa atattaagct
    28681 acgtaaagcg ttaataacat gggtaaatgg attgagcatc actgctactt ttaatcctcc
    28741 agataaactt tctataggga aaagagctga acttaaaaag aaaataggaa gtacaattgc
    28801 agtcataatt gtttcataaa ctatttcatt tggcaataat aaacttatag aataagctag
    28861 acttgataaa aagaaggctg tcataaatat cagtactatc ataagtagga ttccaccaat
    28921 gccagattct atccttactg agaagaatat acttactata cacaaaatag ttacttctat
    28981 gaaagaaact aagatagctt ctaataattg accaaggacg attgaatacc tactgatagg
    29041 tgcaattaag actctataga aacttccact gttcttcatt ataaagttta taataccacc
    29101 actactacaa gaagaaaaca caaccagtac aatgatacct ggtagtataa aagcagtata
    29161 attattgata tttatattat tcatagtttg gtttgcaata gaactataaa gcacaagcca
    29221 aagaaaaggt tgtaatatag taactacaaa tgagattgga tttttaaaac gccacttcat
    29281 actacgccat aagatattta acattcccat tcctccttta agcttttttt agaacttgta
    29341 agtgctaaaa atacatcttc gagacttggc tctacaattt ctattgcatc aaattctata
    29401 tcatgttcta aaagccattt atttattaaa gtaaaagcag ttctactatc gtttacactt
    29461 ataaaaattg aattttctcg tacgctcata aactttacta aaccagtact tttaattgaa
    29521 tctttatatt tttttatatc ttcagtatta tgaaaagtta tacgtagtat attttgtcta
    29581 atgtaactac gtaaacttga tggtgttcct tgtgctaaat cctttccatt cttcataata
    29641 caaatattat cactcaattg ttcagcttct tcaagataat gagtagttag aaatatagtt
    29701 gtgccatact catctctaat ttttaataac atatcccaca tagattttct tgaatcgaca
    29761 tccataccaa cagttggttc atctaaaaat aggattttag gagatgatac catattcata
    29821 gctatgtcca atctacgttt tacaccccct gaatatgatg aagtaggata ttttaagtaa
    29881 ctagataagt caaacttatc aattaaagag tctattcttt gttttgcaat ctgtggttct
    29941 actttataca ttttactttg aaataccata ttttccataa gggataaatg ttcatcaata
    30001 gagatttgct gtgctacaca agcaatttga gtacgtatcc aagaaggatt atctactaaa
    30061 tcttttccaa acattgttac atttccagat gtaggtttgt aaaaggtagt caaaatattt
    30121 ataagagaag atttaccagc accattagga ccaagtaaag aaaaaatttc tccagcattt
    30181 acattaaagc ttagaccatt taaagctttc acaccatttt tatattcttt tactaaattg
    30241 tctatttcaa tcgctaacat atattattcc tcctctttaa gtggaaatat tatctctgta
    30301 atatagttat ctgggtttcc ttttatcaac atacctggtc ctttaataaa tacttctctc
    30361 caaggagttt gtatttttat attattttca tgaatatatt taaatatcat ttcatacgtt
    30421 tttggcaaat tactataaga gcctgtgtga gtaaaaaata aagcttttgt tttaggaaat
    30481 tcttttgtag ttatacccat acgatttgga gtttcagcag ttggaacaca taattccatt
    30541 tctgcaacac cagttttttg gtcaacatca tagtagcaaa agaatggtgc accgttagac
    30601 tttcctttta tagctttaaa tacatttgga aaatactttg ttgcctcagt cataggtcca
    30661 ttataacgca tggtagccac tgtgactgat tcgatatttt tgatttcaat tttgcaattc
    30721 atttgtttac ctcctaatgt gtgttcatat tcttactaga tttttaagca ttaatacata
    30781 taagattttg attagttgaa aacatataat cttatctcgt ttgcttgttt tcaagtctaa
    30841 cataacataa aatatatatc ctctcatttg atgctccatt ttgtaaagtt attatttaag
    30901 ctttacttta gattttttag caaattaaaa taaagcaatt tataaaataa gtatttacaa
    30961 attaagtgta ttaatcgtat aatacactta ataggatact agataaagtc tgaaataaag
    31021 gcgtattttt ttaaagtaag tgtactatcg tattaataca ctagaatagg aggaatcatg
    31081 aattttgaat tagataatac aactcccatt tatttgcaaa tagtaaagta tataaagaga
    31141 caaatagtaa caggagagtt gaaaccagga gagacaatac catcaagaag agaaatggca
    31201 cttaatctaa aagtaaactt aaatacagtt caaagagcat ataaggagat gggtgatatg
    31261 aatataataa atacttttaa aaattatcaa agcagtgtaa cagttgatga aaatatatta
    31321 aaaaatttaa aattagagct tataaatgaa tcactatctg tttttataga agatatgaaa
    31381 gcaataaatg ttagcaaaga agaagtttta aaaataatag aagataagta ttagtttttt
    31441 aacaaataga aaacttagtt tagaaagttt atttataagc atattggatg tggaggatag
    31501 taaatatgat agaaataaag aatgtcagca aaacatataa aaggatgcaa gggcttaaaa
    31561 taagaaagat agaagcttta aaaaatgtaa gttttaatat agaaaaggga aaaataactg
    31621 cattacttgg tataaatggt gttggtaaat caactatgtt aaaagcaata gcaggactta
    31681 taaacattga tagtggagaa attcgtatag atggagaaaa aataaatgaa aaagtataca
    31741 ataaattggc ttttgttcca gatgtacaat ctcactttag caatacaaca ataaaagaaa
    31801 catttgaatt tatggaaatt ttttattcaa agtggaataa agaaaaatca aaagaaatga
    31861 tggacatatt taaattggat gaagatgaaa taattgataa cttgtcaaaa ggaaacattg
    31921 caagagtaaa attaatactt ggattttgcc aagacccaga gtacatactt cttgatgaac
    31981 catttacagg aattgatttg tttaagaggg aagagtttat aggagtaata gcgcaatata
    32041 tggaggaaaa tcaagccatt atcataacta ctcatgagat agtagagata gaaagtttag
    32101 ttgatgaggt tgtaattctt gatgaagggc agattataac ttcatttaat gcagaagaat
    32161 taagagaaag agaaggtaaa tctatattag ataagatgag ggaggtatat aagaatgaat
    32221 aaacttctat atctaataaa tgtagatttg agaagaagca ataagtttta tatagcttat
    32281 atatcatttt tttcattaat tacacttagt ttaaatttat tcgaaattaa taaatttaaa
    32341 aattctaaat ttattatgaa cttagcaata gaagattttg gaggtatatt ttatggacta
    32401 gggatactta gtaatcttgg ttttatccaa agtatattgt tctttgggat attgggactt
    32461 tttatatact atgtttttat gtggaaaaga gagttctttt caaataatca aagtatttat
    32521 acacttatga tgttacctca aaataagttt aagatttgta tatctaaatc aatagccttg
    32581 ataacaatga tatatggttt tttgataagt cagacagcaa cattatttat atgtaaatat
    32641 atatttaatt tcatttttag aaatatgcct ataatcaata tgaactttgc caaagattta
    32701 tattatttaa acttgaagag tataccaatt gattttatct cttttatggc tatttatgta
    32761 tttttactac ttatagctat ttctattgta aattgctgta tattatttat cttttcctat
    32821 ataaataaat tttatgtaat tttaatcact ttgctgatta tagcaggctt atatttttca
    32881 acaatatata taaatataat cactttattt agaaaatatt ataatcttat aggatttcaa
    32941 tttaacaatt tagtagcagg gttattaagt tttttaatta taatgtttat tctaaatgga
    33001 atatcttatt tgctaattaa aaagaaagta tctctttaag gaggggtggt atgaaattaa
    33061 aatctaaaat atctatactt attatatttt tgactttagc aatatatttt agtataggtt
    33121 tattaaataa tgaagataat ttaaagataa aaactataaa aggtgactct aatgaattag
    33181 accatataaa cataaatttt ggatatgctt tgaatggata tataaattca tattatacaa
    33241 taaatggaag caacaaaact aaaaagactg aattaataaa actacaaaag gatagtaaga
    33301 acacaaataa tttaattgat gtatctagtg gttcagattt aattgctcat gttggatttg
    33361 aaatgaatga ggagtcaaaa gatataaact ttgtgataga tgagaaaaaa gaagatttag
    33421 aaaaaggtgt atttccatca gaaggtagtg ataaagaaat tgaatatgaa aaattagata
    33481 tgaataattt tacaaggaca agatataaag tagataaaag tacagatgat tattatgcaa
    33541 agatactatc atcaaaaaga tataaaaaat acttatatgt atctgtactt tatgctacaa
    33601 gtgattcatc agaaaataac aaagaatatt caagtactat agatataata aaaattaatc
    33661 cagaaaataa aaaaatcaag actataaaaa gtataaattt aagtaattat ttttccgaaa
    33721 aataccaaaa catagagaac ataggtgtaa gttatgctag caaatatgag gacaagatgt
    33781 atattttagt aaatgtacta aatacaaaca taggtgataa tagtaattct aaatttcatt
    33841 tacttgagta taatcttgaa gaaaataagg aaagcataat ggaattaaaa actgatagca
    33901 aaatggcttt agcaaaagca aagttagaag ctaataaatt atatatggta atgtcgaatg
    33961 attatgataa tagttcaatt acagagttaa atttacttac ctataatata ttagataaaa
    34021 gcttagatga agataaatat gttttagata atagagaaaa aagaggaatt agaagtattg
    34081 aaattgattc aaataaaatc gttgcatata catcaaggct aaactctata ttatcttggg
    34141 atgataaatt tatgctatat ataataaata aaaattctaa ggaaattgta tatgaaggag
    34201 aattacaatt taacagttca aatagtatgt tagaatttga aataaagtag gtgagttgat
    34261 gaaagattta ataagattat tcgaatttga attaaaaaga aatataaaga attatatatt
    34321 tataataatt tgttgttgtt cttttgtaat tttaaacata gtaaaaaatt taaatgacta
    34381 taattacata atagaaaatg cagttaaaag tgaacagtta acaaaaatcg gaaatacgat
    34441 agaaacggta aatgttacag gtttctcaag ctttagaaat ataatgggtt ctacagaatt
    34501 gtggtttatg tttggtataa ttgcatgtat ttgctatgct ttttttattt ggtatagaga
    34561 ctttaatggt agaagtaaat ctatatatac acttataatg ctacctaaaa atagaatcaa
    34621 tatttatata tctaaattat taaatatatt atttctagtg tatagctata cagtagtact
    34681 tacaatatct ttgtttattg caagtaagtt gttacctaga catatgcttg gtaatgtcac
    34741 aaactatggt tttgtacaag aaacaatata tgagttaaaa atgttacttc catatagctt
    34801 tgaaatacta tttgtagagt atatattttt attgatagga tttgtatctg tagtatttac
    34861 atcaattctt ataaataaat ctatttataa agtaagcact ttaataagtt ttctattttt
    34921 agttatagaa attttagtgt ttataatttc tatagaattt attatacctt acgaatacag
    34981 tgatgtattt actgttctat attcaagtat aaacatattt gtatgtagtc ttatatctaa
    35041 taaacttttg aagcaaaaga ttgactttta ggagggatat tatgaaagca aaaaatatag
    35101 gaaaatatac aatatgtttt ataatagtat gttttttaat gattactatg accttaatat
    35161 tgagttattt taataaggat aaactatctg taaaaacttt aaaaggcaat gtaaaagata
    35221 tagggagagt aagtgtagta tatacaccta atataagcaa attttcttat gaggaggtaa
    35281 ttataagtaa aaatggagta agaaataata caaacccaaa atcaagaatt agaaatgatt
    35341 atttaaatat tgacaaaaaa tacagtgact ttgttaatga taaaggaaaa gaatttatat
    35401 ataaagatga tttgaatata ggagaagcgt atacctctgt taagtctgat ttagtacaag
    35461 gaatgaatgc tttaaatgat tgtataaagg tttcaaataa aaatttaaaa agtggggtag
    35521 aagaaaattt tgatattaat ttaaataagt ctgattttaa agaaaatagt tggaaaacct
    35581 tatttaacaa aatatataaa ggtaatttat atatggtaat tagtgaaact aatatttcag
    35641 gttctaaagt caataatatt tgtatattaa agatagatat aaaaaataag tcttataaat
    35701 tattaaatag atttaattta ggattacaga atggagaaca acaaaatatc aatgaaatta
    35761 aattttctat tggaagtaaa ttatacttag aaatagtaaa taataaaagt aaaaatggat
    35821 atattgaagg acatgatagt tactctaact ttattatata tgatatagaa gataacactt
    35881 ttaatataag taataaattt atggataatc taaacaaaga aaagaatgca aatccaaagg
    35941 agattggctt attaagtaaa actaagctag attatatggt aaaaaacaat aaattgaatc
    36001 ttatagttac ggatatgagt aattccataa ctaatcttgt ttatgatatt aattctaatg
    36061 agattaaatt agaagattat gagatacttg atttaaaagt agattataat gaagcatcat
    36121 ctggagttag gaaagttaag ctactggatg ataagatata ttctatttca ggtattaaga
    36181 acagtatatc aggagaatta aaaggattta aagggattgt tgatgtagtc ggaactaagc
    36241 cagtaaaatt tcaagtattt gatatgaaac ttaaaaagaa tatttatgaa gctgagctaa
    36301 taaatggaga tataagttta caagaaaagt tattttttgt tgcaaattaa gtgttagaat
    36361 taattttaga actttaaact tttatatgta tcacagataa gtataagtaa gggagtgtct
    36421 caaaataaac tttttagctc atgagacact ttttttatat gaaatcaaat atattttcat
    36481 tgtttagatt tattttgata atgaaaaaaa gattatcttt attttaagaa agacatttat
    36541 ttataattat atacaaaaat attttttaat gtttttgtgt ataattataa caatttaatt
    36601 tatattaatg cacttaaatt tgaaatagaa tgcttatagt ggtaaaatta attattagaa
    36661 tattagaaat aataaataaa taatacattg tacttaaaag ggggagaaat ttaagatgaa
    36721 caaaaaatat attaaagcag ggaatttaat tgatggaacc ggaaatagta ttatgcaaaa
    36781 taagggtata attattgatg gagatactat agttgaaatt gaagatataa gagatgattt
    36841 aaatggatat gatgtgtacg attacttaga taaaactgtt atgccaggca ttatgaattg
    36901 tcatgttcac ttgacaatgg agccagttgg aaatccaaag atatattatg ataatgtatc
    36961 agatgtagag cttgtagtaa atacgataaa acaacttgat gcttatttgg attcaggagt
    37021 aacatatatt agaagcttag gttgtcccaa atatgtggat gtacaactta aaaatcttat
    37081 agacaaaggg tctatagatg gtcctggtat agttacttca ggtccagtta tatgtatgac
    37141 aggagggcat ggatattatt ttggtattga aagtgatgga gtggatgaat gtagaaaatc
    37201 agccagaaca gttttaaaaa atggagtaga ttgtgtaaag ataatggcaa ctggaggtgt
    37261 aacaactgat ggagttgagc cagggtcacc acaattaact ttggaggaaa tgaaggctgc
    37321 tgtagatgaa gctataaaag caggtaaaat aactgccaca catgcacaag gaagaactgg
    37381 tataaaaaat gcagtgcttg caggaattac ttctatagaa catggtgttt atttagatga
    37441 tgaaataatt gatttgatgc ttgaaagagg aacttactta gttccaactg tggctgcacc
    37501 atattttatt ctaaatgcag gaaaagaaag tggaataact gaagctactc ttagaaagtg
    37561 tgagattgtt gccattccac acaaagagtc attcctaaaa gcatataaaa aaggaattaa
    37621 aattgcagtt ggttctgatg caggaacttc ttataatgaa catggaaaaa catattatga
    37681 aatgaaacta atgtcagatt atggtatgga taatatggat ataatagttg ctgctacaaa
    37741 aacagcatct gaacttttaa gaattgataa aaattatgga actctagaaa aaggaaagaa
    37801 agcagatgtt atagttgtaa atggaaatcc agtagagaat atagacgtac ttgcagatgt
    37861 gttagcagta tttaaacttg gtaaaaaagt tagataaata gtataaaaat aaaaaagagt
    37921 gtctaaagaa atttttaaat aattatagac actctttttt attagtaata attaaatctt
    37981 ttatacttta gaaaatagat tctattttat atttagatat aactctttaa aatcattctt
    38041 atgcaatata atctatagaa tctacacata caaagtatat tcttgaatca ttagaatttc
    38101 caagtactat aacatcattt ttcttaccta gaacttcaac accagttaga accaaactac
    38161 cagctactac agtaacttga ttatttatat ttgacatata aagattatct aggatacctt
    38221 tattacaaca gcaatcatca caatcgcagt tacaattaca ttctttgtaa tgttttttat
    38281 caagatagta acctaaagat gctatgaaat cttcataatc tgcaggtgta atatcaaatg
    38341 caacagcttt aagattacac aatgatgcta aatctacgtt tgctaatgga gtagatgcag
    38401 caagtataaa atcaattata gcagcaagta ttgcatctaa tatagcccca aggtctatcg
    38461 taggaggaat aactgcatca ataagtgcaa ttaattcagc tactcctggt atagttccta
    38521 tagtattaat taatccctca agagttaaag ggactggaat aggataagat actctaccag
    38581 ctatatctat taaatcacag ttacaagcag aaaatctttc aaaagtacca tcaagtccag
    38641 ataaattatc ttttggagga gctgaaagat ctatacctac caaattagca cctactataa
    38701 agaaatctga gataaaagca aattgattaa agtttacaaa aggtcttaga gcatcatatc
    38761 ttagaagttc taatgcttct ctcatacttt ttttacaaca acattgtttt attttaggtt
    38821 ctttatattt atttggataa ttatagtatc tatcagctac ttgataattt tcatagtatc
    38881 tttcatttgt atttggataa tcttcctcat attcttgtgt aaatctaaag tcctctctac
    38941 atttattatt ttccactaaa tacactcctt ttatatttta atttaaatgt atagataatt
    39001 a
//
LOCUS       DAEPXW010000034        37809 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.035, whole genome shotgun sequence.
ACCESSION   DAEPXW010000034 DAEPXW010000000
VERSION     DAEPXW010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37809
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.035"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            310..708
                     /locus_tag="KRM55_001664"
     CDS             310..708
                     /locus_tag="KRM55_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1593913.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(925..1134)
                     /locus_tag="KRM55_001665"
     CDS             complement(925..1134)
                     /locus_tag="KRM55_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593914.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(1166..1375)
                     /locus_tag="KRM55_001666"
     CDS             complement(1166..1375)
                     /locus_tag="KRM55_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593915.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            1674..2093
                     /locus_tag="KRM55_001667"
     CDS             1674..2093
                     /locus_tag="KRM55_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593916.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            2321..2776
                     /locus_tag="KRM55_001668"
     CDS             2321..2776
                     /locus_tag="KRM55_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593917.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(2983..3243)
                     /locus_tag="KRM55_001669"
     CDS             complement(2983..3243)
                     /locus_tag="KRM55_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593918.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(3506..3859)
                     /locus_tag="KRM55_001670"
     CDS             complement(3506..3859)
                     /locus_tag="KRM55_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593919.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANVEIYEMLLNQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(3876..9197)
                     /locus_tag="KRM55_001671"
     CDS             complement(3876..9197)
                     /locus_tag="KRM55_001671"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593920.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNALISQYT
                     EISLSNVTDAYSSYNATFIVVDEKKVYATGINTNYLLGFSTSDGSNVNLGLLSDWYYI
                     NISGSSYSRVSCTNNITKINNIIIYEYVTVFCTNIGSFLTGYHGTSWTKPTDSSYRVQ
                     YQGISYAGYLDSYIYNYYPTRCTQSSSSTTFAYLYNGESSSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNIFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGLVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(9214..10197)
                     /locus_tag="KRM55_001672"
     CDS             complement(9214..10197)
                     /locus_tag="KRM55_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH1593921.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(10198..10896)
                     /locus_tag="KRM55_001673"
     CDS             complement(10198..10896)
                     /locus_tag="KRM55_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBH1593922.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMISREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(10893..11945)
                     /locus_tag="KRM55_001674"
     CDS             complement(10893..11945)
                     /locus_tag="KRM55_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH1593923.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKMHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(11938..12366)
                     /locus_tag="KRM55_001675"
     CDS             complement(11938..12366)
                     /locus_tag="KRM55_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH1593924.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(12366..12692)
                     /locus_tag="KRM55_001676"
     CDS             complement(12366..12692)
                     /locus_tag="KRM55_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBH1593925.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(12708..14237)
                     /locus_tag="KRM55_001677"
     CDS             complement(12708..14237)
                     /locus_tag="KRM55_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1593926.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(14519..14941)
                     /locus_tag="KRM55_001678"
     CDS             complement(14519..14941)
                     /locus_tag="KRM55_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593927.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(14941..17394)
                     /locus_tag="KRM55_001679"
     CDS             complement(14941..17394)
                     /locus_tag="KRM55_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593928.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(17394..17561)
                     /locus_tag="KRM55_001680"
     CDS             complement(17394..17561)
                     /locus_tag="KRM55_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593929.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(17588..18034)
                     /locus_tag="KRM55_001681"
     CDS             complement(17588..18034)
                     /locus_tag="KRM55_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH1593930.1"
                     /translation="MSENGLLKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(18160..18588)
                     /locus_tag="KRM55_001682"
     CDS             complement(18160..18588)
                     /locus_tag="KRM55_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH1593931.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(18602..19666)
                     /locus_tag="KRM55_001683"
     CDS             complement(18602..19666)
                     /locus_tag="KRM55_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBH1593932.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(19671..20114)
                     /locus_tag="KRM55_001684"
     CDS             complement(19671..20114)
                     /locus_tag="KRM55_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593933.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTLTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(20363..20803)
                     /locus_tag="KRM55_001685"
     CDS             complement(20363..20803)
                     /locus_tag="KRM55_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593934.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(20908..21105)
                     /locus_tag="KRM55_001686"
     CDS             complement(20908..21105)
                     /locus_tag="KRM55_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1593935.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQS"
     gene            21274..21594
                     /locus_tag="KRM55_001687"
     CDS             21274..21594
                     /locus_tag="KRM55_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1593936.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            21676..22182
                     /locus_tag="KRM55_001688"
     CDS             21676..22182
                     /locus_tag="KRM55_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593937.1"
                     /translation="MNNLDKLFELASQEGIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            22883..23638
                     /locus_tag="KRM55_001689"
     CDS             22883..23638
                     /locus_tag="KRM55_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1593938.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(23781..24209)
                     /locus_tag="KRM55_001690"
     CDS             complement(23781..24209)
                     /locus_tag="KRM55_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH1593939.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(24630..24830)
                     /locus_tag="KRM55_001691"
     CDS             complement(24630..24830)
                     /locus_tag="KRM55_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1593940.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(25013..26182)
                     /locus_tag="KRM55_001692"
     CDS             complement(25013..26182)
                     /locus_tag="KRM55_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBH1593941.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            26418..27239
                     /locus_tag="KRM55_001693"
     CDS             26418..27239
                     /locus_tag="KRM55_001693"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBH1593942.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(27315..28703)
                     /locus_tag="KRM55_001694"
     CDS             complement(27315..28703)
                     /locus_tag="KRM55_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBH1593943.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLFLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVCNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(28838..29596)
                     /locus_tag="KRM55_001695"
     CDS             complement(28838..29596)
                     /locus_tag="KRM55_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH1593944.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSSVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIACNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     SYQSTGLICGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(29598..30314)
                     /locus_tag="KRM55_001696"
     CDS             complement(29598..30314)
                     /locus_tag="KRM55_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH1593945.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLICSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(30316..31023)
                     /locus_tag="KRM55_001697"
     CDS             complement(30316..31023)
                     /locus_tag="KRM55_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH1593946.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGE"
     gene            complement(31139..31675)
                     /locus_tag="KRM55_001698"
     CDS             complement(31139..31675)
                     /locus_tag="KRM55_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1593947.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(31777..32847)
                     /locus_tag="KRM55_001699"
     CDS             complement(31777..32847)
                     /locus_tag="KRM55_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBH1593948.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHDEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(32840..33898)
                     /locus_tag="KRM55_001700"
     CDS             complement(32840..33898)
                     /locus_tag="KRM55_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBH1593949.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(33885..34217)
                     /locus_tag="KRM55_001701"
     CDS             complement(33885..34217)
                     /locus_tag="KRM55_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH1593950.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            34416..35537
                     /locus_tag="KRM55_001702"
     CDS             34416..35537
                     /locus_tag="KRM55_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBH1593951.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(35665..37563)
                     /locus_tag="KRM55_001703"
     CDS             complement(35665..37563)
                     /locus_tag="KRM55_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBH1593952.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
BASE COUNT        12291 a         6338 c         4069 g        15111 t
ORIGIN      
        1 tatttttctc ttaatctttt tctcttttac agacaatcaa aaagcaatct tagtttatcg
       61 aaataaattt atacaatcta ttcatacacc cctttacatt tatataacaa ttaaacctat
      121 tgttatatat acaaatcaaa ataaaccata tattttcaac tataatatgt taaaatcata
      181 ttatgagcat attaatttaa gcaaaatgtc atttagactt taatttagta gttttatatt
      241 ataaatttat atatttttaa ttttaaatgt catttagaca ttactcataa aaagaaagga
      301 gtgtattttg tggatacttt aggaaaaaga attgcttatt tgagaaactc caaaaaactt
      361 actcagcgca aacttatgga tattttaaaa tttgaaaact taggcaagta tgaaacagga
      421 gatagaaaac ctaattgtga tatactaatg tcaatagctg attattttaa tgttacgact
      481 gactggcttc tctatggtaa agagaaggta aatgtcaata gtagtgtaaa agaagataaa
      541 gaagattact tacatgttac taatgatgaa atgacgatat taaatctata cagacaacta
      601 aacgaacgtg ataaaataaa aatagaagga atacttgaac ttaagatatc tgaatataaa
      661 gacttaaaaa agcattcctc taataataat gaagataaaa tggtttaaac atacataatt
      721 tgatacgatt ttacatcatc tattaacctt ctttttttgt agtatattac taaaatatgg
      781 atattggatt atttaaaaac aagtatagtc taatttcaag cacatttata atatttagat
      841 tatcttatcc atattttagt ttaagtactt tgaaaaatat aatacatctc tatgtataac
      901 ttatattcct aagaaatgca ttactcatgt ttttaattct tccaacatct ttctatacac
      961 aattgtacat ccttcataat tcccctcttt aagaaggatt gaacatgtac tagaatattt
     1021 agttaaagta tttaatcttt ccatatttaa gctttttata ttactgagtg ctgtaataaa
     1081 atcatcaatt gctctacaac actctataac cccatctgaa tccaatttac acacaagaat
     1141 attcacctac tttatatact atttattaat catcttctga atattctata ttaagtaatt
     1201 gataaattga tgatttatat tttttacctg ttcttcttcc atttaaaata gctgacaaat
     1261 agttttcatt aacacctatt ttcttcgcta attccctttg agtcatattt aattcaataa
     1321 gtctttgctt gacttgcact cccaaaaaag gtatccattt ttttcgagca tccatttatc
     1381 aacttccttt ctaagcgatt tatatttact tttatattat tttagcttac gcaccccctc
     1441 tatttagtat atatttttaa tatgtacaca tattaagtat ataaatttat ttaatactaa
     1501 ataagatttt ttgattactt tgtgctaaaa ttaggatgta aattcgtatc attaagttaa
     1561 ttataaagtc attttgacct taagtcaatg gtttttatgt cattttgacc tttaatttga
     1621 aactatttac atcttaaaaa gtctttttga cattaattga atggagagtg tttatggata
     1681 ctttaggaga aagaattgtt tatttgagaa aagcaaaaaa ccttaaacaa tatgaactag
     1741 aagaaatgtt gggctgtgac aacttaagta aatttgagag aaacattaga aaaccaaatt
     1801 atgaaatatt aaaatctata gctgagatat ttaatgtttc agtagactgg ctattaaatg
     1861 gagataatct atcacataaa tcagatttaa tttgcgattc ctcctcaaac tatccactta
     1921 atagcataaa ctctaatgaa ataaagcttt taaacaattt tagaaaatta aatgattatg
     1981 ataaagctaa aatagaaggt atgattgaat taaaacttca tgaatatgaa aaagagaagg
     2041 atttaggaaa aattgagtat aacaaaaata aagatgagaa aatagataaa taatttttat
     2101 gttgcttttg atacgatttt acatcatttc tttgttctaa tatttttatt tcatttattt
     2161 tcttttttat aattttatga taaaataatt agtatatttt gctttacttg aatgtaatta
     2221 tttatacaaa agtcaaacat aatataaatg tagtaaattt ttagtttcaa gtaatatctc
     2281 gttattataa ctaaatattt attaaaatta ggaggataaa atgggcttaa gagacaaatt
     2341 cgcgcaatca tttgctagat caaaaactat gagtggccct gagaaaaagg ctaatgaaat
     2401 aatgggtaaa ttgcttctta agaaagctat attacctatc gttttaatgt tcgtgataat
     2461 aatcgctgga gctatgctta aaatcaattc ttgggttaca cttggcataa atttagttat
     2521 tgctgttggt gctttcttct acataagaaa ttctagtaaa aagtatcaga actttaaacc
     2581 ttatgttggc aatttgatta gtttagagaa aaaaggtaaa aaagagtacg ttgctattat
     2641 aaaacaaggt aagttaccag ttaagttaca aatagcttat ggtggtgaag accttgaaca
     2701 tgttaagaaa aatcaaatgg ttcaaataag ttataatcca gatgctaaaa tagctatttt
     2761 ggttaataga caataattta ataaaaaaaa ggagttgtct taaaattgat tttttctaat
     2821 caaatttaag ctcaactcct tttttaattt ttatatgtta tttttattac tttttttaat
     2881 taatatttta aatattaaat ccttctcaat aaaatagtga actatctaca atactacttt
     2941 atcttttcct aacaatatat aatctggtgc tactctttca tgttatacac cattttgtaa
     3001 catacctttt atatcagtaa catcttcctt aatttcctct acatctgttt tcattatacc
     3061 catttgaaca agtatatttt tgtttatttc ttgttgttgt gtagataatt ctataaaatt
     3121 ttctacagtt tttttataca tgtctctatc ttcttttttc tcctgcatag tatttttaaa
     3181 taatagagca catagtatac ctattgcccc tagactactc aattcggtta ttaatttatc
     3241 cattatagcc tcctattgtc taaatttttt atacttatag ctttaatttt tgttgtattc
     3301 ttacatcatg caatattata ttttcaggat tatcaattta atcttctgta ctttaaattg
     3361 taggtgtaat ttatagattg aataaataat aaatatatat acaagttcta atgtaacaaa
     3421 aaataagtac aaggcttact tattaaagtt aagaccttgt actttacata aaaaaaataa
     3481 ctaatacata gttattctaa atttactatt caactggtat ttctaattct ttacatctaa
     3541 ttctaacttg ctctctaatt actgctggta cttcttctat tgtttttttg cctcttaaaa
     3601 ttaaagctac atatacttct accattccac tctcacctcc agattttctt acactaaaag
     3661 tgcttatatt acttgcttca ttgacagaac tttgatttaa caacatctca tatatttcta
     3721 catttgctat aaaattattt gttatatcat catcttgctt tacttgacct atacttatgt
     3781 ctgaaatgtc tttatactgc atttctactt ttctaccttg tttgatttgt tctattttat
     3841 ttttatcgaa tttaaacaat tttcacacct ccattttaag cttgtggctc gttgttttca
     3901 gcatcatatc taaaaatcat agatggacgt tttatagctg tccatttatc tcctttttct
     3961 actatgattt taggctgagc actttttatg ttggcttctt ctaattcata gatttcttgg
     4021 taacttgagt ctgatttttt gatttcaact agtttcatgt ctttgaataa gtcagattta
     4081 tttattttta cttgaacttt agttttattt attaattgat atataggatt gttttccatc
     4141 atatcatcct ttaatccctc atttaatgtt actattaagt cagtgttatt ttcagtaatg
     4201 tttatgattg aatatacttt attgtttatc attaaaatag aatccttttt tactttaagc
     4261 cctgtttctg atttaaatat aaacatactt gaatataaat cgcctgtagg actactggct
     4321 ttaatcagta tcttattttc tcctaatact attttatttt gtggtatctc aaatataatg
     4381 ctatttattt ccaaattagt cttagtagat attaattcat catttataaa catttcaagt
     4441 ttttctataa cattattagg gtcttgtact acaactctca cttgagatat tgatttttca
     4501 actatttcta tagatgcttt acttgtatct acttttgtta tcatgtatat tgtatcatct
     4561 gaaagctcta tatctaaaat atcatttaga tgttcaggaa ttggtatttt agtaaattca
     4621 tataaatcag taattgatat agatatttta tacatagatt tatttttacc agttatccat
     4681 agactattat catttttaat tactagtatg tggtcatcat tatgtgactt aatttcttta
     4741 acattagtta atactttagt aaaagttctt attatcttat ctttttcact ttctcctagt
     4801 ccaaataatc catttgtatt gtacccttga gcgtacaact ctccctcatt agttaaaaca
     4861 agtgtcattg agttatatat acttatatct ttaacagaag gtaatccagt aaccttttgt
     4921 aactctctta catcattatt gtggccaact cccaattggt actcagtatt ctttccatat
     4981 gaccatagag tattatctgt cttaataata taggagtagt tatctccaca agcaactttt
     5041 ttgacatctg atatatttac ttcagtaaga gttaataatt ctatatcttc aagggtttga
     5101 ttaatttctt tatatgaatt acttcctatt ccatataact tgccatcctt agcaacagcc
     5161 aatgaatgtg tttttgatat atcaatatca gatacctcaa atggcaatat tattgaagta
     5221 tacttaaaat tatctttaaa tatgttttta taatttatat acttattatt tgtttttata
     5281 tacttatcat taaacattac tagcttttca tttttcttat taaaaactat tttatctgat
     5341 gtgttatctg ttttaaaata tgaatgtagg gaaccttcaa gagcttcatt tttatcatta
     5401 tcatatctat ggtgaatacc taaatgatta tatctattat ctcctgttga agaataaaat
     5461 tttccatata tatctttaat aaatatagta ttgtaactag aaaatacagt atcaacatct
     5521 ttctttatag atactttata atatggaact gacatatccc tataagattc atcagatata
     5581 ccataagtat ctctacctga tgatatcaaa ttgttattat tatctatata aagtgtatta
     5641 ttagctgtta caaaaacatc tttaacatct tccacactat ttgtattatt attatttgct
     5701 atacttccat atccactaag acctccaaca aatagtttat tgtcatttgt taaaatggct
     5761 gaagtatatc cattaactac tatttttttt gcatttataa tattattaat tactcgtatc
     5821 ccctttatat cattagtctc tgttgaaaag aataccctct cttttttccc tgtagtataa
     5881 atcatattgt catttgttat aaaaaatgta gcttcacttc ctgctgtcac aacagatttt
     5941 acattctcaa tatttatttt tgtaaatgta cttatacttc cttcagtaaa cccaaaatag
     6001 ccatttacaa gtccacatac atagcatgta ttatcatttt taacaatgat tgatacatca
     6061 ttacatagat atacatctct aacaccattt ataggtatac gtgtaaatat attcctactt
     6121 gtagtatcac ccaatcctaa ctgtcctttt ccattattac ctgctccata taaaagacca
     6181 tcattagtta ataatagaga tgtgtttcca tatacagcta catattttac attttcaaca
     6241 tttattttag taaatatatt tctatttaca ttatctccta ttcctaactg accagaatta
     6301 tttaaaccaa cagcataaca ggtattatca ttttttatcg caaatgcatg tttactattg
     6361 tcagtaaatc tatttacatt tatagatttt atattatcaa tatttatttt agtaaatacc
     6421 tttctattta tctcatctcc cactcctaat tgacctacat catttaaacc aacactgtaa
     6481 agcatattat tattagttaa taaatatgta gactttgaat ggctatatat ttcttgtata
     6541 ttagaagata tttcactact gctattcttt ttattgtaat ttatcttatt atttaaattt
     6601 aaactactat taactgatat accatgcgta cccttagagt tatatccaca tataaataag
     6661 ctcttatcag ttaatattgc aaatctagtt ttatctctac ttaaatcata aggaggtata
     6721 aatatatttt ttatattttt cattaccttt ttataattag tggcattata tccatcttgt
     6781 gtatctgaaa catctagttc ttttgcactt tcagatatat tcccaaaacc atatagcgtg
     6841 ttagaagata aatacaatag agctttatat aaaaatatgg ctttatcaga ggtaatagga
     6901 cctgaattta tattagatgc tgcaatatta ttagatgatt gattgttaag ataattcctt
     6961 ccatattgat gtatataaga tgaacctcca gaaataagta aattatctgg attgacattt
     7021 tttaaattac ttgacgattc cccattatat aaataagcaa aagttgtaga agatgatgat
     7081 tgtgtacatc ttgtaggata ataattatat atataagaat caagatatcc tgcatatgaa
     7141 attccctgat attgaactct atagcttgaa tcagttggtt ttgtccatga agtaccatgg
     7201 tatccagtta gaaaagatcc aatgtttgta caaaatacag ttacatactc atatatgata
     7261 atattattaa ttttagtaat attattcgtg catgaaactc tactataact tgaccctgat
     7321 atatttatat aataccaatc acttaataaa cctagattta cattagatcc atcagaagta
     7381 ctaaaaccta acaggtaatt tgtatttata ccagttgcat ataccttttt ttcatcaact
     7441 acaataaatg ttgcattata tgaactataa gcatcagtta cattactaag gctaatctca
     7501 gtatattgac ttattaatgc attactaagt ccattaacat aacttgaact ctttccagaa
     7561 gtgtatattt gcttattatt agttacaatt aatgaaaacc agtttgataa atcagtattt
     7621 ataacaactt tttttacatt atctatagat attttcttaa atacatctga attagaagga
     7681 agaacacctg ctattgagtt actatttggt ccagaataat aacaagtatc atcattttta
     7741 atgtagaata ttcctccaga aatatttttt gatgctacta tagactttac attagagata
     7801 cttaattttg tcaactcatt taattgactt ggtaagtcag aacccattcc tttgtatcta
     7861 ttatttccta gaccatatac atctccattc cctaaaataa ccagagtaca ataaggacta
     7921 aaaacgacat ctcttacaga atgtatatct agtggaagtt caatatcctt tatttccatt
     7981 tcttctttta ataaagttaa tttatcctca gatttaatta aatttatata attactataa
     8041 ctatattttt cactatccat tttcttaaat tctacaatgt gcatatcatc aaaaaacgaa
     8101 cctaattgtc cataagtatt atctcctgta caatatgaat cattatttga atcaattagt
     8161 atgctatgtg ataaaccaat gaaaatattc ttagctacaa tattttttaa atctataaat
     8221 gaattatcta tattctcaga gtaatttgct atacctaact gatatatatc attatttcca
     8281 gcaaccttta aagtaccttt gttatctata agcatagtgt taccatgacc acatgcaata
     8341 gtttttatat ttacttcttc tatcttagta aatagtgatg attgaagtgc atttccaaaa
     8401 catttttcct ttccacaacc atatatatca ttattatacg tcattaacac agtgtgttca
     8461 gaaccacaag ctatagtctt aacatcatta atagaaacta aactaaataa atctctatta
     8521 ttcttatctc ctaaacctag ttgaccttga ttattaaaac cagtagaata gcatttattg
     8581 tcattcttta ttataaaagc tgatttatta tatgaaaata cagcctttac attgtcaaca
     8641 tctacttttg taaatgtatt tacatttgca gatgctccat tagttcctag acctaattga
     8701 ccatacaaat tatttccagc aacatataaa gttccatcat tgtataaaag atatgttgat
     8761 tgaagtccac atgcaatatc ctttacgcct tttatttctg gaaccttctc aaatgtagaa
     8821 actgttttcc ctactttttc taatcccaat cccatttgac catctgtatt tatacctgcg
     8881 acaagtaatt ctccatctga agtaagtata actgcatgag attctccaca tgcaactttt
     8941 ttaatattgg tagatatatt tggtattttc gtaaataatt ttcttgttgt attgtcttct
     9001 cccaatccaa gttgaaagtt actattatct ccacatccat acaagatatt attatttttt
     9061 agaccaaatg tatagttaca acatccagta aaaaaattaa taaagtcata attatcatac
     9121 ccttcatcaa attcatcaac taccatattt ttatcgccaa agaaattacc tctttgaagt
     9181 agtttagttc ttttcattat aaaaacctcc taattatctt atttcatacg aatatttatt
     9241 taaagttata tctgtctgac caattgaata tgccctatta gattttgttt caacaaagtt
     9301 attatccatt tcatgtatat atctaactct atttgcatta aatggtagca ccacattctt
     9361 aaatgtaaca ctaccaagtt ctccagttat acactttcta tttaaatcta acttaaggcc
     9421 ttctatagct attatgtttt tagcattagt taaggtatca taccaatatc cagcttcatc
     9481 tacatctatt tctgactcta attctaagta tattaagata tctaatactt tttcagataa
     9541 tttattgtaa ctatttttta atacagatag ttcagtttgt atttgacctc ctattacatc
     9601 atcaatagat atatttttaa ttttttctac tacctcattt atagctcctg ataagttttt
     9661 agcttctgta gataagagtt cttcgccaat ttttactttt atttctttta tatttttatc
     9721 aaacttatca tctaaatctt gaatatcctt ttgagttaca aaaaccaacg tcgggtctac
     9781 ttctaatgta acatttgaag tattggacaa ttgtaaaatc atttttacaa ccaaatcttt
     9841 aatactgcca tcttcagcac gtggcttata cgtctctgga tacttaccta tagctattat
     9901 attattctca ttatccagaa cagcagcttc tcttatcata aatccaccaa ctgttcctgg
     9961 taaaatagtc tctataacta tccaattagg atttttttca tcaattctta gagaatttat
    10021 atttccttcc caaactacat tctttaaagc agtttgttcc tctgttggct cataatattc
    10081 tccattacta tctccaactt gaaacttggt taatccaaca agctctccta gtgcagttgc
    10141 atttgctatt ttttctctac caattttggt taatattata taaaattttt cttccaatta
    10201 taccacctcc gatttaggat aaactactac attttctaca cctgtatcat ttgcaatagc
    10261 tatattaatc ttacaattat tttcaatgca tttaatgctt aaaggataaa cctttatttc
    10321 ttctctactt atcattccag ctccacagtt tacaacagca ctacatttta taattggttc
    10381 aaagtatgga tgaactttta cctcttcact acataccata cctccaccac aatagaccat
    10441 acttttatct agtattattg gttctaaata gtgtaataag tgagcaggtt ttactctttc
    10501 aatcatatcg ctacaatcta aaagagtttt atagtcacag ttatttgcta taaaactcaa
    10561 tacgaatgta aattcatcac tataaacttt tatatctgtt tctgattttg tatatgcctc
    10621 acatatactt tttataactt caatagtact agtacctctg cttctcattt tagcttttat
    10681 attgctacgt cttgtgtcaa aatcaagttc ttttttttca atgcagagta tgtcttccca
    10741 catatctaat ccccatgttg cagtgtcaac aaataattgg ttaaaggtat catcaatatc
    10801 ttctttaaga atatttaatt ctgtatcgta tgcaccttgt atctcctcta caatgtaatt
    10861 tctatcaaat gatggtagtt tatcaattag cttcattgat tttccacctc actaaaatta
    10921 acagttgtta cactaggtat tttatcttca ttaatagtta tattatctgt acttccattt
    10981 ataagtaggt tacttaaatc gtgtacacca gtagtattta taagtattcc cattactttt
    11041 gtatagatta tctctcctct aatatctcta aagtatgtat ttatactttc taggaaagat
    11101 tcttttacat tgtctaatgt atatccatct tctagtttca ttactgcact tatacttatt
    11161 tctattggta atggtgtcac aactgttata gttggtccaa taggcttctc ttcatctata
    11221 tgttgctgac acctttcaat tgtttctgta tcaacagctt gattattttt cccaaatatc
    11281 aagaccttaa ctgttcccgg accatcccat cttggataaa ccttaacatt atagactcca
    11341 tctacttcca aagcccattc ttcatagtga gctttatttc cacttgtagc ttgatttctt
    11401 tggattttat aaaatctttc ttttagttct tcatctgtct ctatatctgt accaccttca
    11461 aaacttcttg tgttagtaat ctttgttact ccagatatat tatcaactag tttaaattca
    11521 caatttgtag gtaaattata tttcttacca acttccagag cttgaactgg gctattgtca
    11581 ccttcttcac taccaatagt tacatctttt attactacaa atagtaaatc tctatatgat
    11641 attattgtgc cattatttat tacagtacct ttctctccaa taaattcaac ttctccattt
    11701 gactctgtac ctaactttct atatacacca aattcattga ctcttttatc aagaaactgg
    11761 ttatatgtgt cttgtataaa agccatttta tgcatctttg aaagttctag atatatcttc
    11821 gaaagttcta gattatttcc agataccatg ttgtttagaa aagaaccttc tcctttataa
    11881 atatcaagat taatattttc aagagttcta ttttttatta cttcatatgt ctggtcacta
    11941 tacatttatt tccacctccc catagatagt ggatactttt acatttgcac tcaatatgtc
    12001 tctgttaaag ttagcacttt ttacgtttac ttctaatata tatggattta ttagaagggc
    12061 ctcttttatg aatctactag cttcactttc tgtaagacct tttgtatatt tttgtcctat
    12121 tagttctgaa agctctgtcc catattctaa agagtatatc tcatgttcat atctatttgt
    12181 ctttatacac ttgtatatcc aaacttttaa ggcttctttt ttttcaatta ttttaaagtc
    12241 acctttttct aaaataggtt catctttttc aaaatcccat gccacttcac gaaagattgg
    12301 caattcttct gttttaggta agatataatc ctctgggaca cctataaaag gaaatattgt
    12361 actcattata agctcaccaa cttacttaca acagcaaatt tttcgcctat tctaaacatt
    12421 attaccatat ccccagattc aaagttatct ataaaaggat tttttacttc atgctggtgt
    12481 tcttgatttg tttctgtgtc aaatgtttct agctgtctat caatcatcca actatctatc
    12541 aaaatatctt ctttttctaa tatgatgtta tttgtctcta tttttaaatc tggtaattta
    12601 cttttaattt ttccaataaa aaaagaaggt tgattatgat actttccttc ttctcttatt
    12661 attcctataa attcatttat tggattagcc attatatcac catcctttta taatactctc
    12721 ctagctgtgt taaaatctct tctactactt aacttactta ttttaactac atcacctttt
    12781 tgtggagcat gtaaaaattc tccattacct atatataatc caacatggct gactggatta
    12841 tgaaaaaata ctaaatctcc tgcttgaaga tttttttgtt ctactttctt gcctttttta
    12901 gattgttgat ttgacgttct tggcaaacta acattaactt ttttaaaaca atagaccatt
    12961 aaaccagaac agtcaaaact acttggtcca tttccacccc atttataagg tttacctaga
    13021 tgtttttttg cttctgatat tactatttta gctttatcag atacattacc agaataacca
    13081 ccaataataa tttttccttt tcttcttcca aatttactag cttcttcaac atttccaaat
    13141 aaaatatcta tatggtatgt tccattcttt tctatagtta ttgcaggtcc tacgtcattt
    13201 actttataga ctccatcacg accagaaact cctgtaatta cctgtatttc atctccatag
    13261 tttaataaag gatgtttatt taaaaactct tttgtataat aagtttgctc atatttacca
    13321 accataggag cagcgcaagt ttttttagat gggtcaagtt ttttctttct acaatctgta
    13381 tctccacctt cttcttttct aggacagtaa gctgtaaatt ctgctgtaaa ctcttttcct
    13441 cctgcataat cttctccccc taaattactt tcttccttag gttcatcctg tcctgctgac
    13501 ttttcatcca taagattttg aaaattaagt tcaagctcaa tttgatattc tccattttgc
    13561 caagtatgtt tgtctgtatc tatataaaat agtcctacaa gctttgtata agaatcttta
    13621 acttttactc ctctaccagt tatacaactt acatctccat aacctttaag agaacagctt
    13681 ttttctatcc cattaaactc gctatcaata tctacatctt gattttcttg ttgctgaatt
    13741 actttttgca ttattacatt tacttcctta aaaatttcat tatctatttt ttcgctaatc
    13801 ttgcttccat actggtctac cactattact ttatttttta cattttccat gctctccgaa
    13861 aaggtggtat ttataatatt aaatccctct tcaaacataa cacttaatgt aacagttcct
    13921 ttttcaataa cattaaactt atctaaattg gcctctatca tatacttttt ctttgtcttt
    13981 ttacttgctt ctgtatatgc actcattatt gtgtcataac catttactcc tataaacatc
    14041 tttgtatact tgacattggt ctttgctatt gttccaactg aaagcctatt ttcagcaaat
    14101 acttgctttg ctatgtcttc aactaactta tctttaaaat tgtatgacac ttcactttgt
    14161 gtaagtaaaa atcccatatc tttagataca aaactaattt cattactgct tgaatcttta
    14221 gacctattaa ttatcattcc tctaaagagt tctttctcat ctacatagaa acagactgta
    14281 ctagctattg gtatatcgat ttgttggaaa tttacatcaa atgatgattg tattattgaa
    14341 aactctagtg tccttgatgg agatttataa tcacctgacc atgatacctt gtctactatg
    14401 tcagttatgt catatatact tccgtttttt atgtgtaccc aaatcttaat aataaaaaat
    14461 cacctgcctt ttcatttaat tctatcagca gttatttata acttattatc tataatagtt
    14521 attgttttgg agttactttt ggtatcttta ttcttttata ctcttttaaa tctaatgtaa
    14581 aatatacatc tcgagtccca tctctttctt cataactaaa cccttcaatt atgacttcca
    14641 tatttatatt tgtttccgta attgtaaatc ttaatataaa accttccttc atccattttt
    14701 ctatcttatt tacacaatca tatggtgatg gaaaacctgt atagtcacag aaagtatagt
    14761 ctttatttgg aaaaaaactt gatattgaaa tgcttttaag agctacacca ccaaaagttg
    14821 ctatttcacc tattttgagt atactagaag agtttacagc agcttttcca ttaatactaa
    14881 aggaagatgg aaatactgga aatctaaatc tatcttcagc ttgtctaagc cacatttcca
    14941 ttataagaca ccccctaact gtgccaattg gatacttgca actaattttg atgttatctt
    15001 ttctatatca gcttcttctc taatcactat tgtatcagct aacttagcta tgtttatatt
    15061 tccaccattt tttctgcttc tatattgatt tgcttcttgt ttagttaaaa ccatttcacc
    15121 ttcatggagt ctggtttgat agtcattata aggaacatag ttcaatccaa atgcattatt
    15181 acctttctta cctgaataag ctttaccaga atcaccagcc tttgttccag catatggatt
    15241 atctttgtaa ttttttttac tcttttccac tagatttaaa actgttcctg tgatgcttcc
    15301 attttttatc ttattaatca tagtttgcca ccacttgcat atatctttaa ctattttaca
    15361 tactttatct aatatgttaa aaaaagctcc caatattggc tctataattt tccatccagt
    15421 ttccaacaga ggtcctaagg tctcccatac agttttccaa ataacaccca gtgtctctat
    15481 aaaattgttt atttgaggtg catattcacc taaaaaagta aaaattcttg tgataatagg
    15541 actaacagct tcaactacag gtccgattag ttggaatgct gtagttacta ttgtaccaaa
    15601 tatacttatt aatccttgtg caattggtga tttattgttt atactatcta gtaaattatt
    15661 tactaagttt actactggaa gtaatgaatc tattaatgct gtaaaatcga tattttgtaa
    15721 tagtgtactt cctgcgttaa caattgcttt tggtgcattc cctatcattg ttgctgcatg
    15781 attttcaaaa cgttcttgct tattttcaac catcatttta cgcttttcag cctcattaga
    15841 aattcgatat tgagtagaat cagaaaactc ttttccattt tttacacttc tagattgcat
    15901 ctggtcatat ttgttgccaa taattatctt accattcatt acattgccta ttttaccagc
    15961 cattttttca gataagccag ctaaattgcc taatccactt tctataaaag tttttatttt
    16021 ctttagtcct tgacctaaaa tatcatcaaa aggtttaaca atactcttca agccattgtt
    16081 aatgcttgtt tgagctcctg atattatacc tggtattgta ttactcattt ctttagctaa
    16141 ccccatctgc tttacactta tgccttccaa tgcttcatca aaagttttat aattttctcc
    16201 taccagagta ttaagagatt ccatgtttcc ttttgctgca cttaagaaag ctgctgatac
    16261 atcttgttca ctacttgtat tcatatttaa agctctaaca tctaccatag cttgagttat
    16321 atctttttct tttttgccac cagtaatatt actaatcatt ttagctttag ttcccattgc
    16381 aacaacatct tcagggtcaa aaggcgtatc atttgccatt cttactaaac tgccataata
    16441 atcatcaaca tctatttgat taacttttcc agtatttctt ttcattacac tttctagaac
    16501 aactttctga ttttgttcct gaccaagtaa atcaacaccc tttttcacag cgacacctat
    16561 agtagcacca tttgtcaaat cagatatctt cccttttatc gaaccaagta ttccacttgc
    16621 catatccttt acagctattg caccactcca taccttacct gcaaataatc tcaatttggg
    16681 aaatacttta cttataatgc cacttgccat atcttttata gctattacac cactccaaaa
    16741 agtattttta aacaacatta acttaggcaa aattctaccc atagcactac tcaccatatc
    16801 tttaagatta atacttcctt gataaggacg tttctctact tgttttaatt ttcccaagat
    16861 actacttatc actctcttag tcatatcttt tgcttttatt acgatattcc aaatcttgcc
    16921 accaatcttt tttaaatttc caagtaattt atttttagtt ttttctactt catcactttt
    16981 agctttaaat attaatataa tcataatatt tgaattaaac tcatttttct tttgaatcaa
    17041 cttattaaaa taatcaataa tcatagctat agttattgct agtctcataa tacttccatt
    17101 taaacttcca ataactcctg aaacagcatt tatgctagaa cttaattttg tcatagttga
    17161 acttacacta ctagcagtag tttgaacttt tcttaacgag gaatttaaac tgtttactct
    17221 attacttgca cttccaatag aattttttat gctactagcc attacattag tggaaagtga
    17281 aacagccaca gttgctctcc taaaattatc agttactgat ataatttgat tcatttttgg
    17341 tgtgtaatta tctgtaaggt acatatttat accttcttct ctcacatttc ccattacata
    17401 ccacctcctg tcaaaggaca cactccatat ccatgtttca ttttttcaac ttcttcctca
    17461 atttctaagg cgaaaaaagc ttcaataagc tttaattcgc ctttatccat tgcataaaaa
    17521 agggacggtc ttataccttt tttcttccaa taatagtaca ttattgtagt cctggtatcc
    17581 gtccctatta gttttttacc tcttctatca ctgcattttt accataaccc ataacatctt
    17641 gaagtattct atataagttg gtaatttcac ctggtaataa caattttctt gctaattctt
    17701 ttggtgttgg agccttaaat ttatccatta gctccttatt tttaaataaa agctttccat
    17761 ccaaatcaca aacaccttct ataattgtaa gcatctgcat ctccggtaag tctatatccg
    17821 ttttcatatt ttcatcaatt ttaagacaag tattttgtat ctcttcatct ttacttattg
    17881 ttaaagctct acacattact ttaaattcct gcccaaatat agttgataat ctcttaagtt
    17941 caactatagt acttggtctt tctaagtttt ctgtatctgc atttaaaagt aaatctacta
    18001 tgtttatatt ttttaataat ccattttcac tcattattat ttgctccttt atcaatcaaa
    18061 ttcaatcaac taactttttt acttattaac tatctgaatt tattaagtat atatttacta
    18121 aatatcagta taaaaccaaa tataaaacta aatataaaac taaattatat caagaaaatc
    18181 atactcagta aatgtgaaag gtgcttctat ctctcctttt acgccaacct cccaatcagc
    18241 taaagttaaa tcatcaaatg ctatattctt tactgctatt ctttctgctc cataagaatc
    18301 tgggtcattt aatttagata tagcaacaaa tctaggttca gaacctctct ttatcttttc
    18361 tccaattaac ttgtgcattc ttgaactaac atggtataga gttattgagc cttttccttt
    18421 atatcccata tactttgtat cagtacccat ttgacctgct attataatat cttcttttgt
    18481 aaattccatc tttgcttgaa acttctttac ttctgctact ttgtttccat caagccaaag
    18541 ttctccccaa gtaccactca ttacatttct agcttccata tttgccatat taataatcct
    18601 cctatatttc tattgataaa tctatatctt ccatagcatc aagtactttt atttttgctt
    18661 ttaaaaatac tttagaacct gtgttagctt cttttatttc ttgtaatgtc atataagata
    18721 aatctactcc ttttgatttt aaatacgatt tttgtgcttc aaaatctatt tcaacagtag
    18781 aatcagattc tataagtgct gatttttcta attcttctaa ataacttttt atagctacta
    18841 tcaataaaca tttgttgtca taactgttag taacctttcc tatatagtca tctattatca
    18901 cctttcttat gtcactatgt ataatatcta aagtgtcaac tatttttatt ttctggaaca
    18961 tttctccttt ttctgctgtt aattcagtta aagaatttac tcctctagca attcttatag
    19021 ctcctgcttc tttaataagt ataagctctc ctttattaac ctttgattct gcatcaactt
    19081 tcgtcatctt aggtatatcg actacatcac taagtttagt ataagttact gattgactta
    19141 aaggtgtacc tgctataagt ccagccaccc tacttgtaaa ctcatcaaca ctgtatttct
    19201 tttctccaac taacacatct tctgtagtaa aattaattat cccttcatga tttcctacaa
    19261 cttttcctaa tacagcttta accttaacct tatctatatc tctaagttta attatccaat
    19321 tttttatagc agtcttatca gcttctactg cttttggcat acatagataa ttaaattcct
    19381 tagtctctaa aaaatctaat gcagtttgaa tatctgcttc tccttctatt acataaacta
    19441 ataatttatt tggagtgtta acatttccca tcaaggctaa atttatatat tctttatttt
    19501 cagcagataa atcaactggt atatcctctt tttcatgtat ttcattaaga cctagtgcct
    19561 tagcatcttt aagcaccatt gcaattattc ctctagctga acgttcttta acagttgtag
    19621 ctagctcctt aaatgatatg ttgatacttg gtaatcctat agccatacta tcactctcct
    19681 aaatttaaat tgatttcttc catattttca tatactacat cttcttcata tacactatcc
    19741 agatagttta gtgtaagtgt aaagttcaat acataaattg actcttcttt tttaatactt
    19801 tgttctagct ttgttatatt taattttctg tctgttacct ttatatttct gttaaatagc
    19861 ttatttaatt catctgaaac ttcatacatt ctaatactct ttgactgtgg ttttggtaag
    19921 tattttatag agataacaat atctttgtta ttcgtattta acattacagg tgtacaaata
    19981 actgatagta tacttacaaa aaaacaagac ccttcagagc cttgcacact ttcatcatca
    20041 ataaaaatac tttcagtaaa gttttttttg agaatctcaa taattgtttc taatatttcc
    20101 ttgtatttaa gcaaataatc accacactat cactaaatat tcttgcttaa tctgataatc
    20161 ttactataaa tgatataagt catttttaaa tatatatctc atttattcct gtcaagtatc
    20221 ttctatattt ttaggtaata ttattctttt caatctatca cctccttcaa tatggatttc
    20281 tttcacaata acattatctc acatatttta ttgcctattg ttgcaatggt gtatataaag
    20341 tgttgtaaaa ttgtcctatt ttttataata tctcactcaa tttaaatatc atctttttct
    20401 ttaaattgta gcaagatgtt ctatctaagt gtagtttcat agaaatatat gtcatattgt
    20461 tttttgtctt actattataa aaaagattaa aaaattccat ttctatatca tttagacacg
    20521 ttagagcatt ttctatcttc tctttttcta tttctatatc ttctttttcc atttttaatt
    20581 ttcttaatct ttcctctctt tttaacacct cattttccac agaagagctt atgttatatg
    20641 tgttactagt cttttctgta tataccattg ctccacatcc agagtattca ttctcacatc
    20701 tttttatgtc caagttaata ttctttatct ttatatccaa atacttataa ttatgtaatc
    20761 ttttatctgt ttctttaaat aatatatctt ttttgttttc catagtactt ctcctttttt
    20821 atatacttat tattagcttc aaatttacaa taatctcttt agtgcacagt tttttactaa
    20881 tctcacaact ttcaagaaca tattgttcta tgactgtata aaaaaaactt cttctatatt
    20941 ttgttctaaa atactagaaa tcttcttagc cataagaagt ccaggatttt ttatgcctct
    21001 ttctatttga gatatataat catttgtaat tccagccttt ctggcaagtt gaatttgtgt
    21061 catacctttg cattttctat aatatttcaa gttattttta aacattgttt tatacctcca
    21121 ttactattaa gaatattttg ttcttcctca cttagattat atagaattat ttgttcttta
    21181 tcaatatatt ttagaaaaaa atattctttt atattttatt agttttattt tttagaacaa
    21241 tttgttataa tctatacata aggtggtgtt ataatgtttg ccaaaagatt aagagaactt
    21301 agaaaggaat ttggattgac tcaaagagaa cttggagaaa aagtaggcgt ttcccaaaga
    21361 gtcttagggt actatgaaac agaaaacaga tttcctgatg aacacatttt aaataaattg
    21421 gctgatgtat ttaatgtatc agttgattac cttcttggaa gaaccttagt taaggaaaat
    21481 attgatacag tagctgcaca tagaaaaaat ccacatgaag agttacctga agaagcacaa
    21541 gaacaactta atgattatat agaattttta ctaaataaat ataaaaaaaa ataaaccata
    21601 tgatgagcag tctatttttc tgctctttta atataattta aaggcaaaca tacattctat
    21661 tttaggggga tttttatgaa taatttggat aagctttttg aattagcttc tcaagaaggg
    21721 ataataattc attataccac ttatattgca ggtgatttag aaggactata tataaacaaa
    21781 catggtatta aaattatatc attactcagt aatttaaaac aaaactcaaa aaaattaaca
    21841 tccatcttag ctgaagaact tggacatcat ttcactagcc ttggatacta tgtatcctct
    21901 tataacgatt attatacaaa aattattata gataagtgcg aaaataaagc cttaaaatgg
    21961 gcttgtgagt tcttaattac tgaagaagat ataataaaca taattaactc tggcatcacc
    22021 tgcgtttatg aaatggcaga catacttaat gtggatatta ctttctttca aaaaagatta
    22081 gaatttttat cattaaaaaa acagtcttta caacttggaa ataataaata tttaatatta
    22141 actaatttgc cgtatttcta catatttgat ccaatttcat aataaaaata gtagtaattt
    22201 taactggctt aacagtaaaa tctatatatt tattttaaca aattttggtt tctataaatt
    22261 caatattaat atataataat gatatcatat tatttaaaat tctaaaaaca aatatatgct
    22321 tttgttaaga aaggttgttt gatgaatgta taaagaaaag ttgtttgata attattttaa
    22381 gttcttagca ctattatttt ggccaattat gtggtataag tggatagtaa tttcaaatgg
    22441 tactcttgaa aatatgttat ttaccatata tgcaatcgtc gcaattgttt tcatcatttt
    22501 atattcggtg tttatgataa aatataaaga cattacacaa atagatttct tttacaggat
    22561 aagtactcta cttgctttta tatttacact ttttagcttt ttaatatacc caaagagttt
    22621 atttttcttg tatttaaaga ttatttttac tggaatatac ctttattatt caatagtaaa
    22681 aactcttaaa tttaaagatg acgaaggtgt agtgggtatt atgagctcac ttttattaat
    22741 tgtaataact ttgttctact aaatttaatt ctatttgact taatatggct ttaaatatta
    22801 gacatctaca ttattttctg atattattta agatggtagt cttatattaa taatgaaata
    22861 cactatgaag gagttaacta ttatggaaaa aaaagtttta gcaacagttg gagaaaaaga
    22921 gataactaat attgatattg aaaatgcatt aaaatcatta gacccttatc aagctatgca
    22981 atttaaaact gaagaaggaa aaaaacactt attaaatgat ttagtgaatc aagaattatt
    23041 cttcttagat gctaaagaag aaaaattaga tgaagaagaa atatttaaat tagaaatgaa
    23101 aaagatagaa gaaaatgtat taaagcaatt tgctataaat aaagttttat ctagtgttaa
    23161 tgtaacagaa gatgaaaaag taaaattctt tgaagctaat aagagctctt tctctaaacc
    23221 agaaagtgca actgctaaac atatattagt agatagtgat gaaaaagcta aagaaatact
    23281 tgctcaaata aaatcagaag aaatatcttt tgaagatgca gctcttaaac attcttcttg
    23341 cccatctaaa gatatgggtg gtgatttagg aacattcggt agaggacaaa tggttcctga
    23401 atttgaagaa gctgtgttct ctatggctaa aggtgaagta agtgaaccag ttaaaactca
    23461 atttggatac catataataa aattagaaga ccttcaagaa agtacagagt ctacatttga
    23521 tgaagttaag gctgaagttg aaaaaagttt attatatcaa aaacaaaatg aagtttatgg
    23581 aaataagata aatgctctta atgctaagta cggaaacctt gtaaaataca acgattaatc
    23641 ataaggtcat atataaaaaa gctgtctttt cacaatattt attagaaaag acagcttttt
    23701 atattaaagt ttaaatattc agtttcatat tatcattctt ttattgtaaa gaactcagct
    23761 taaaagttta aataagattt ttaattatca ttagctaaat ttttatatcc acgtattatc
    23821 tcataacagt aacctattac atctcttctt tttattatcc caataaatgt gtcttggtca
    23881 tctataacag gaatgaaatt ttgatttaaa gattttataa ctaaatcttc aatatctgcg
    23941 ttgatggaaa caggagaatt atccattttt ctatttatat ctgtcactgg aacatcttcc
    24001 aatcccttta agtccagatt taaatcattt tttaatgtcc ataaaaaatc accttctgtt
    24061 atagttccaa catatttacc atccttactt attattggaa ttgcagagta tttgtgatat
    24121 tccatttttt ctagggcttg ccttatagtg tagtcttcat atatatatgc tacttcactt
    24181 tttggtgtta gaaagaataa tatgttcatt acactaccca ccgttactga aaacttataa
    24241 atattactca atatttataa tgttactttt ttgcagtaac tttctccttt cttattttct
    24301 aagtattctt aatactatac gctgtaacaa gcgtttttcc tttgctcatt ttaatcttat
    24361 tatgctttat taatattttt atatggtcta tcagtatcac ttattctctt tttagaaaat
    24421 ttactaaaaa ttaattgact taaacttagc cataataatt ttactctaca ctattaattt
    24481 taacatattt atctcattat taatgatttt attttaataa ttttaattta ttttgctatt
    24541 aattttattt acaaaaactg aaaaaaccgc taaatgatta gcggcttatc tctcatatta
    24601 ctagaacact aatatatatg aatttttaat tataatctaa ctacgttagc agcttgagga
    24661 cctttagctc catctactac ttcgaactca acgctttgtc cttcttctaa tgttttgtat
    24721 ccatctccag ttatagctga gaaatgtacg aaaacatctc cttcaccttc tacagatatg
    24781 aatccaaatc ctttttcgtt gttaaaccat ttaactacac cagttttcat taataaatcc
    24841 tcctaaaaaa acacaaatat ttagctactc ttttctgtaa ccttattact actctatcat
    24901 atatagctat gtttgtcaat tattattatt tttatacatt aataatcaat ttttttactt
    24961 tataatttta aatgattatt atcttttaca ctttattttt ctttataatt ttttaataat
    25021 ttatttttat tatatggaat cttatggact tatcactcca gcctaaatcc catggcacca
    25081 acattctatc agtattatgg caagttacca aaggataccc tcttgagtct aatcctgtca
    25141 ctgtcgaaac atgtgttatt ctgcctttct tctcataacc aacaaaatcc cctggacgta
    25201 aattataagc ttctttgtat acttcttcat aggaaccttt agcaattaat gaacctcttc
    25261 cactatacag tgcataattt ttaaaagctt gtgcatttac ccatgctttt gtacctgctc
    25321 tctcgctata attccaaatt gagttctttt tgaaccttcc actttcaaac attatctgtg
    25381 atgcaaagtt tgcacaatct ccaccttctg gattataatc cctatagttt ggattaaatt
    25441 tcataccatg ttcttcatca gctgcggctc cacagtattt atgtgcataa tctatagcct
    25501 ttttttgttc atctgtaagc tgtaactcta caccatcttg ttgaccaata tagtttctta
    25561 tatcatcaga ttttatattt tctaaattta aagagtctgc aaaagggtct gtataccact
    25621 ctttagttat gacatattga ttatctataa tttttacatt tagataatga tatgtaccta
    25681 ttctaaaggc attttctttg tccttttgat tttcatatga atacttatat tcagtcgata
    25741 ctgaacagat tataccatag aggtcttttt ctttttcttt tattttttta atcttaaccc
    25801 ttgtctttat gtctttaaat tttacacctt gcttactaga ccagttttct aaatacttca
    25861 tcttttttac ttcattttca taagcccaca gaccaaattt tttatccgtc tcataaagac
    25921 cttttaaaat gttttcattt ttctctaata ttgccttatt tctgtagtca aataagtttt
    25981 caagcaatag tttatattgg tcttttacat catcaccttc aacatttgca gattccatga
    26041 ctttttcttc catatttttc atacttaaat cattgattaa aaatacacct gctgtagtag
    26101 ctaaagacaa aaatacaaat gccattatac ctttgatgta cttattctta tttttcagta
    26161 ttttcaaagc tacacctccc aaatagtaca ccttacaaat caaattacaa agaatattct
    26221 gtcacatata gtaattttca tatttaataa ttctctattt tattatgtcc aatattaaaa
    26281 attaattgta tcaatacact gtttttttta caatttttta ttttataatc tacttttttc
    26341 ttttttttat agtaatatat atgtatataa atattttggt atcattataa ttaatacata
    26401 ctaatggagg gttttttatg caaaaaaaag tcgcagcaat taatgactta tctggaatag
    26461 gaaaatgctc attatcggtt gctataccta tactttcagc attaaaggtt caatgttgtc
    26521 catttccaac ggccatactt tcaagtcaaa ctggttatcc tgaatttact ttcttagact
    26581 ttactgatga aatggtaaaa tattcaaatg tttggaaaaa tttaaaagtc aattttgata
    26641 gtatatatag tggttttttg ggttcaaagc atcaaattga gatagtggct aattttataa
    26701 acgattatcc caatgctttt atcgtagttg accctgtgat gggtgataat ggagttatgt
    26761 atccaatatt cacagaagaa atgagacagg aaattaaaga attagttaaa cattcagatt
    26821 taactactcc taacttaaca gaggcttgtt tcttgactgg aaatgattat actaaaagcg
    26881 attataatag agatgagctt atatatattg caaaatctgt atctgatttg ggacctagca
    26941 aagtcgtgat tactggtata ttagaagatg ataatatatt aaatttggct tacgatagag
    27001 ataatgacca tgtattcttt acatcagtca aatataataa ttgttcttac agtggaactg
    27061 gagatatatt cacatctata ctttgtggta tgttagtaaa taaacatgat ttgggagtag
    27121 cggttaatac tgcaacagat tttatatata aaactataaa ttacacatct caatttgata
    27181 ctgatagaaa tgatggagtt atgtttgaaa actttttatc agatttaact aatatataaa
    27241 gtcaaaaaaa ctatccattt tataaatacc tataaatcat aaaatttagg tatttacaaa
    27301 atggatatta tttactaaac tattggtatt tcaattgtta ccatagcacc accagttttc
    27361 acagaatttt caatatataa aatcccatta tgtttttgta caatattatt tacaatatag
    27421 agtcccattc cataatgaga tttagaattt ctactcaaat ctcctgtata aaactgttct
    27481 gtagcttttg acaaatctgc tttagaaaaa ccacttccac aatctgtaac tacaaatttt
    27541 aagtatttat tacatactga tacacttatg tatagtttac tctggcttgg tgaataatct
    27601 atagcatttg aaattatatt cataatagct ctgaataaca gttctctatc tatagttata
    27661 tttttaggca aattatcttg tttataaaac tccacatcta agtttttagt actagctaat
    27721 gcttctattt gcactaagac atcttttata aactcactca tactgattgc ttctttattt
    27781 aatatatagc cattctctgt ttttgatata tctattaaag tattaatata tttttctatt
    27841 tgagtgacac cctttgagat atattccatg tattctaata actcaggatt ttcatttatt
    27901 tcaattaata agtcagtatt tccatgtata attgttagtg gtgtttttat atcatgtgcc
    27961 agtgcagata tctgttcctt tctattttct tctagcatcc attgtttttc taaagaatct
    28021 tttaacgcca acttcatttt atccatagaa aaaaggacat tattaatttc ataaatttta
    28081 ctagattcta caacaaaatc taaatcctgt tgttctattt tttctgtagt attttttaaa
    28141 agctccattt caatattaaa tttcttgcca aatacttttg ataatataac aatttcaata
    28201 aaaaatatta tactaaaaat aatcataccc aatgtctctg gttttggtaa atatgctctt
    28261 aaaattggag aactatactc tgatactatt ttgtatttta ttataaaaac ttcatctttc
    28321 ttaaaaaact ttatataact ttctgaatat gcatgccttt cttcaatatc tctcattaaa
    28381 ttccatactt cttttgattc ttttttatta aaggtacctg aaattaaatt cccatctaaa
    28441 gtataaaccc catactcata tatacttgga attatatctt cagttacttt ttcacttgaa
    28501 ataatctgtt ctttatattt attaaattgt ttttctgcat aattagctgg taaaattaca
    28561 cctgatgata ataatacaga aaatgataac attaaaaaga gtacaattga aattgtcata
    28621 ataaagaata aagataaata ttttataaaa atagttctta acttttcaac ttttttgttg
    28681 ttagattttt tacctccaag catttgtacc ctgtcctcca atagtttaat taattcataa
    28741 ttaataccca accagttttt tatttgatta ttttatatct ttttattgct aagttatatt
    28801 ttaacataat aatataaata aacagtcaat ttttactcta ttcttctgat tttttacctt
    28861 cccatttaga aaaccaaata cataaaatta caaatgctaa aattgttaca aaaccacaaa
    28921 ttaaacctgt tgattgatat gattttattg attcaacctt tatatattca accgttttag
    28981 aacttgaaaa agacgaccaa atagttataa atctaacacc ccatgcacaa ggaaaatact
    29041 gccaaatacc agaacccaat ccagttaata ataatgctga aagtaacatt tcaactatac
    29101 ctactccaat tgatgttcct tttccgaacc ttaaacttaa gaataaatgt aatatgtatt
    29161 caaataaatt acacgcaatt aaaattagaa ttgaaatcat ataaaagctt gatgtaaagt
    29221 aagccttaga tataccaaat ttaaaaccta atacagacac taatgttgct acaaaaccaa
    29281 gacatactaa gattatatat ttacttataa gagtaagata ttttggatta gatgttgtta
    29341 acatatgttt ataattccct gcataatatt cttgttcaac aaacattgaa cacacaacac
    29401 ttgacaataa aggaaaagct attgctataa cttgtaaata tgctactatc tttagtatat
    29461 tatcagctcc tgaaacctta taataccata aaaacaatcc catccccatt aaagcaatgc
    29521 aaatgtgcat tagtattata aaatttctct ttaattttat taaatcagaa caaaatattc
    29581 ttattaactg tctcatatta cttcacctct ctattattga accaaaccct tgtagctaaa
    29641 gcaaataata caaataaaac aatagatatt aatactcctg gcaaaataac agcattattt
    29701 aaaaattcac ttccctctgg tacaggaaga ccatttggca gaatatgcaa tacaacagcc
    29761 attaatcttg aaggaatcga atatggaaac atataccaca tttctgtagt tgagaaaaca
    29821 gcaactccaa caatagtaaa gaacatattt attagaactg taacaaaaat accaaatttt
    29881 gaagctaaaa acatacaaag aggaatctgc cacataaata gtaaaataat taatatagtt
    29941 gcaatgatat tttgacctat tgaaatagtt tctttataga ttatcccaac aaaaactaca
    30001 cctattgcag aaataattga tgctataaaa cagcaaataa tacagtaaat catttttcca
    30061 gtccaaacat ctttcatttc aattggcaat ggtaaaatac cacgatattt acttttttca
    30121 tcttttaata ctattaaaga acatattaat gttaatgctc ctggaagaaa tgtcgtatac
    30181 caccagttaa aagcagcatt ttgccctcca cctagtccac acaaaagtat acaaaacact
    30241 ggaactatcc atatcaactt cattccaaaa gttcctttca tcttttgaaa ttccactcta
    30301 ataaatcttt ccatattact cccctctctt tctattttca gctacaactt tcataaaaag
    30361 ttcttctaag ttttgttctt ttgatacttc tccttgataa cccattactc cattagaaat
    30421 tattcctatt tcatctacaa cttgttcaac ttcagacaag atatggcttg ataaaataac
    30481 tgtaattcct tgttttggaa aagaacgaat caattctcta agttcttcaa taccaatagg
    30541 gtcaagacca tttgtaggct catctaagat taaaagtttt gggtgattta ataatgcaat
    30601 agcaatacca aggcgttgct tcatgcctag agagaattga cctgaacgct ttttaaaggt
    30661 atctcttaaa tctacagtct ctaaaacttc ttcaatgcga gagtcaggaa gaccaagtaa
    30721 agtagtatga acttttaaat tttctcgtgc tgttaaattc tcatatatag caggagactc
    30781 aataagagaa ccaatatttg ataaatcctt tctagtccat ctatgtccct caaacattat
    30841 ttttcctgaa gttggattta aaatcccagt tatcattttt aataaagtag atttcccagc
    30901 tccatttggt cctaataatc catatataga attagattta attgctagtg aaatgttatc
    30961 aactgccatc tgctccttaa attttttaga aactcctttt acctgcaaaa tataattact
    31021 cataattttc atcctttctt ttgtcaaact tatttacaag aatcattcta aatcataaat
    31081 ataaggattt tataagaatt aaaaaacaaa aaaagacgtg ttaaaaacac atcttttttt
    31141 atcttaattc tattaatttt ccattgtagt atatctctac ttcttcaatc caaatgctat
    31201 tatcttcttc ttggatgaca tttttaataa tattatttat agtatatatt atattttgtt
    31261 cattcaaata atcatctttc caagaaactc tacttttttt atctggttct atcaagttta
    31321 ttttaacaag attatctttt tccttaactt ctacttccat gtctaaacca ttaaaatact
    31381 catttgataa tgtatctaag attaatcgca gtttatcctt aagtgaactt tcttcatcaa
    31441 tctgtaagta ctttactatt ttctcatcct ttgaaattat ctctataggt attttagtag
    31501 tttttttaga attaatcatt ttactagttg tttcttcttt tgcatcttca tccttcttta
    31561 caactgctga ttctttagaa tcaactagct caactgcact gatgctataa tccatacatg
    31621 ccgtactcaa taaagtagta gcaattatta aaaaacttac tgctatttta ttcataagta
    31681 tccctctcct aattctcttt cgatacttat tataccatag tatagattat atttttatac
    31741 ttttaaatca atttataaat tattatagta aattatttac aattctaagc tatttgaatt
    31801 tatttttata gtatattctt tctctaaatt cgacagattt ttattcaaaa gcccttttat
    31861 ttccctcgta tttctatact tgttgctatg ttcttcatca tgttcatagt catatgaatc
    31921 attgtcatat tcttcatcat tattaaattc ttcaattgct tcttttgact ttatatcaca
    31981 attaaattta tacttattta ctggtatatc aagtcttacc ttagaatttg gaacttctat
    32041 gtccaggaac ttagcaattg gcatatcaga gtacaagtaa aattcacttt cataatttga
    32101 atttctacct attttctctt ttatatttac attttcaggt atatactctt ctatattatt
    32161 gataaataca tcttcattct ctgaagatat atacaatgac tctgattcta tgtttacatt
    32221 tttaacgcct aaaattgatt ttgttgacaa gtgaagattg ttattagata ttaagtttag
    32281 gttttctaat ctatttactt tgttctctgt tatagctcta ctaaaacctc cataagaagt
    32341 tttatatgtt atagtatttg aagctacatt atcgtataca aataagtgtg agcttatact
    32401 tgatgcattt atgtctacat tatttggtac atatattata atttctctat aatcatgtga
    32461 aaacatacta tttatagatg tatttaataa ttggtcgaaa tttttaatct ttttaatttt
    32521 attttcatat tttctttcac cttttacaac taaagtctta tcttttaaag ttacattgta
    32581 tttgtaaaac tcattatttc ctcttgttgt tacacgcaca tcttcacttg aacttttctt
    32641 tattgtaacg tttatattgt caacagctat atctaacttg tcaatattta ctttttcttg
    32701 ataaagttta ttttcttttt taaattcagc ttccttttct aaaccaaagt ttattaggct
    32761 tggcataact aaaatccctg accatgttgt ccctattata cctattacca ataaaaccgc
    32821 agcaaatata gcaagttttt tattcatgtt tatcttctcc tttcttattt tctatatctt
    32881 caaggtcctt atatatcgcc tcaaaattta tactatcatc attatattca tcagtttctt
    32941 ttatgctttc ttcttctcta ttgtagtaat cattattata tgaatcttca ttaatgtctt
    33001 tattcaaatc ttcatcattt aaagtagctt tttttctttt ttccatcttt tcatttgctt
    33061 ttatataaat attttttctc tttatccaat gtatataatt atttagtaat tgtttaccta
    33121 gttttatggc aaataataaa atttgccatg caagtatctc aagccctaca aatgctatgg
    33181 ttgcgaaaat acaaaacatc ataacatctg gaaccattgc tataaattta atcacaaatg
    33241 gaattaatat aacaaaagca attaatgagc atactaatgc aatagtagca gatacaatag
    33301 cacatacaaa cgcaaatgct ggaacaatta gaaataaaga taacactact aataacccct
    33361 ttataacttg tctggataat cctcctacac cttcttctat acttggtgta agtttatcat
    33421 ttatattttc ttttgattta ttgtactttt ccttagcttc atctttcaag atagaataat
    33481 ccttttttac atttgattta aatctactaa atttaccatt taatatgtct gtattcatta
    33541 tttttccatc tatattttct tttgatttac tatacttttc ttttgcttca tcttttaaga
    33601 tagagtaacc ttttttcata tctgatttaa atttactaaa cttatcattc aaaacatctg
    33661 tatttattat tttttcctct tcaatatttt tttctttagt ttgtaagata agttcttttg
    33721 ctatagattt tggtgagcca agtgatgcta ttatctccat atcactcttt ccctctataa
    33781 gaccatctac aaaatactct tcataatctc tcaatatatc attaacttcg ctctcagaaa
    33841 aatctttttt tagataatcc tttaaaattt caagaaactc agttttattc aagttcatta
    33901 cctccctcat cttcacttat taaaatctca acagccttta caaattctct ccactcttcc
    33961 atcagattgg ataaattctc ttttcctagt gaagttattc tatagtattt tctagcagga
    34021 ccttcattag attctagtat atatgtttcg aaatacaaat cttttgtaag tcttcttaga
    34081 ataggatata ttgttccttc atttacatct attactttag agatgttatg tactatctca
    34141 tatccataca tatctttctt agatatgaga gcaagtacac aaatttctaa aacacccttt
    34201 ctaaattgtg tgttcatata ctccatcctt tctttaaata cacagtattg tgttttacaa
    34261 ggtactatgt taaaacttct tatatcctca taataacaca gtactatgtt ctgcacaata
    34321 gttattttta aatattcttg ttgattaaat ccttctataa atgtataata ctctaatcag
    34381 atatatttta tgaaagtggt gataaattgg ctaaaatgaa agatgataaa acaatattaa
    34441 tcctaactgc tcaatttggt gctggacata taagtgctgc aaaagcagtc aaagaatgta
    34501 ttattgaaaa atatagtaac tataatgttg ttatacaaaa ctttataaat gcaagtattc
    34561 ccatgatgaa taagcctatg gtaaaacttt atgaaaacaa tacaaaatat actcctggat
    34621 tatataatta ctattattac tttaagaaat cgtttgattc aagacatgat ttatctcata
    34681 aattatatac acctaaactt tctgagtata ttgctgatat aaatccagat ttgattatct
    34741 ctacatttcc actagctgct gcttgtgtaa ataactttaa gataaaaaat cctgatataa
    34801 atatacctac acttacagtt ataacagatg ttgtagatag tatggaatgg gtttttgaaa
    34861 atacagattt gtattttgtt ccttctcctg aaataaaaaa tagatttttt cagaaaggaa
    34921 taaatcctga ctccataaag gttactggag ttcctgttga taagagattt caaattgaaa
    34981 gtaaagaact atgttgtgat aaatatagac tattacttct aggtggagga agaggtctat
    35041 ttgatataga tgaggatttt atgcattgga tagatgaatt tattgaagaa catagtaatt
    35101 ctatagaaat tacaatagtt actggtaaaa acaaaaaatt atatgacaat ctaactcata
    35161 aaaaacctct aaaaaatatt aaagtacttg gatttgtaaa cgacatgtat aatctaataa
    35221 gagaatgtga cctaatgcta actaagcctg gaggagcaac tatatttgaa gctattcaat
    35281 cacaaactcc agtactcgta aaaatgccaa aagttggaca agaaattgaa aacgctaaat
    35341 ttataataga taagggtctt ggcatgattt atagtgatga cctagacctt aaaaacatat
    35401 tttataaatt agtatcaaat gaatttgatt ctataataaa ctttatgaaa aaaaatttaa
    35461 aagaatttaa aacagtcatt catccagaga aaattgctga ttatatatca gaattaatag
    35521 ataatcatta cagttaaatt gtactattaa aaaatttcaa acataaaatt aaaggcaatc
    35581 aagtatgatt ttacacttga gaatttactc atagtgttta ataatacttg attgccttta
    35641 tcatatcaaa atcaaattgt tatattagta tatatttttc ttgtactgca tatacagttg
    35701 ttgtatttct tccatacttc tctttaattc tatttgtaaa tctgaagcag tctggtaatc
    35761 cttattttct atagcttctc tcactctagt gaatagtgat tctctagtta aagtatcctt
    35821 cataatattg aactttaaat ccgatattga gttccaaact acctcatcaa gcgcatccat
    35881 attttctttt gtgtgtatct tgacaatact tcttattttt tgaatcccag cctctattat
    35941 tctagttttt aatttctttt gccacttatc tatagctcca atcttaaatg attctattat
    36001 actatcagta aatacatcac cttgttttaa agattttaat tttgaagcat atatttctaa
    36061 gtttttcata ttttcataaa ctgtagctgg tggtattcca aatcttgcat ttctttcttc
    36121 caaactataa tgttcaaata catcattttc atctctatat gctctatctt tttctaaata
    36181 gaaactttct tcacctacat ttttagataa ctctttttca agttcttttg tactaagacc
    36241 actcttagct gctgctttta taccatccaa cattgtttga taacatcctg ctattactaa
    36301 atacgtgtta gatagagggc ttggtgacct taattcaaat cttacagtct ttggattttt
    36361 catatctctt attaatccaa caagcactga cctatttctt gatggaatct cataactatg
    36421 ccctaaagat gtaactatac atacaggagc ttcaaatcca ggaactaatc tattaaatcc
    36481 atcattagaa gctgttacaa ttgggtttaa tacttcataa ttgtaaagaa gtcccataag
    36541 agccccatat cctagttcac ttagataatc ttcttttaaa tcttttggag caaatagatt
    36601 ttttatactt ccatccttta acttcgcact tactcctaca tgtgtatgtc caccacttcc
    36661 tgctactcca tgaattggtt ttgctttaaa tgtaacttct agtccatgtg atgtaaatac
    36721 atcctctata acatctctta ctaataattc attgtctgct gcttgtaatg gtgtagaaaa
    36781 cttccaagaa acctctaatt gctccatagc atggtttgtt cttccatcta tactaataga
    36841 actttgtatt cctccgacct ctttgtgagc catttcaggg tttacaccta gcttttgaag
    36901 tataattaaa cttttctcta aacaagttct tataatacca tgagttcttt tccagtattg
    36961 ctcttttagg ctttgtgata catataattt ctctaagtca gctttatcct caggagtatt
    37021 aacccagaac tcaagttctg tagctgctgt taacattatt tcctctatat catctactga
    37081 atctattcct atgttattta ttacatgtgg atattctcta aatatttcat acattgactt
    37141 tttaaagtac ttatctgctt tttgaagtac tcctctagaa catacttttt tattatcatg
    37201 tattaaaaat gcaggtatct ttaatgttcc aacaggtaga cctacttctt cgtctatata
    37261 ttccatattg taatctacat accaatgaca acttttatct ggcattaaat ctactttcgc
    37321 attatttaat gtagctatat tataaagctc aacacttgaa ccatcagtct gtatagctga
    37381 ttccaaaaat ttatctatat cctccaaaaa taattctaca ggaatctttt catctgttgc
    37441 atttcctcct aaatcaaccc ccattaagga aacaaatctt atatttttat tgctttttag
    37501 gatttctctt aattcttcat tagtgtgttt atctttctct attacgtata atagactatc
    37561 catttttcca ctctcccata atttttatgt atattttatt ttgttaaata caagataaat
    37621 ttcattttcc ttacatttat gaatttttct tgcaaattat tcgtgtttta ttcgtgtttt
    37681 tatttatatt attatatatc aagtataaaa agttcgcaat attttttatt ggaaaaaata
    37741 ttatacatac aatagtttaa catttttaca aatatggggt atactaaaat aaaagtattt
    37801 ttatttgaa
//
LOCUS       DAEPXW010000035        36640 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.036, whole genome shotgun sequence.
ACCESSION   DAEPXW010000035 DAEPXW010000000
VERSION     DAEPXW010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36640
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.036"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            23..799
                     /locus_tag="KRM55_001704"
     CDS             23..799
                     /locus_tag="KRM55_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH1593953.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(891..1643)
                     /gene="xth"
                     /locus_tag="KRM55_001705"
     CDS             complement(891..1643)
                     /gene="xth"
                     /locus_tag="KRM55_001705"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBH1593954.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(1804..2754)
                     /gene="galT"
                     /locus_tag="KRM55_001706"
     CDS             complement(1804..2754)
                     /gene="galT"
                     /locus_tag="KRM55_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBH1593955.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            3139..4335
                     /locus_tag="KRM55_001707"
     CDS             3139..4335
                     /locus_tag="KRM55_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1593956.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(4447..5787)
                     /locus_tag="KRM55_001708"
     CDS             complement(4447..5787)
                     /locus_tag="KRM55_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1593957.1"
                     /translation="MKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVVEE
                     RQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKIPL
                     QFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALKRV
                     FPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDLVP
                     KIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKVAK
                     SNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAHNK
                     HQIAIVITENNGAISNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAYEK
                     LAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(5926..6678)
                     /locus_tag="KRM55_001709"
     CDS             complement(5926..6678)
                     /locus_tag="KRM55_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1593958.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            complement(6826..8403)
                     /locus_tag="KRM55_001710"
     CDS             complement(6826..8403)
                     /locus_tag="KRM55_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1593959.1"
                     /translation="MKQKMKGFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     MPFLANNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGILAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYAIVYYNVFKILILRFNLQTPGREEITDINFDLKPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKDNIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            complement(8815..9267)
                     /locus_tag="KRM55_001711"
     CDS             complement(8815..9267)
                     /locus_tag="KRM55_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1593960.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(9578..11023)
                     /locus_tag="KRM55_001712"
     CDS             complement(9578..11023)
                     /locus_tag="KRM55_001712"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBH1593961.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(11167..12075)
                     /locus_tag="KRM55_001713"
     CDS             complement(11167..12075)
                     /locus_tag="KRM55_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1593962.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            12332..13156
                     /locus_tag="KRM55_001714"
     CDS             12332..13156
                     /locus_tag="KRM55_001714"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH1593963.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIWLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            13196..13726
                     /gene="lepB"
                     /locus_tag="KRM55_001715"
     CDS             13196..13726
                     /gene="lepB"
                     /locus_tag="KRM55_001715"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH1593964.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(13808..15589)
                     /locus_tag="KRM55_001716"
     CDS             complement(13808..15589)
                     /locus_tag="KRM55_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBH1593965.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(16224..17765)
                     /gene="rny"
                     /locus_tag="KRM55_001717"
     CDS             complement(16224..17765)
                     /gene="rny"
                     /locus_tag="KRM55_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBH1593966.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            complement(17941..18987)
                     /gene="recA"
                     /locus_tag="KRM55_001718"
     CDS             complement(17941..18987)
                     /gene="recA"
                     /locus_tag="KRM55_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBH1593967.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGISVSKEIVEE"
     gene            complement(19275..19817)
                     /gene="pgsA"
                     /locus_tag="KRM55_001719"
     CDS             complement(19275..19817)
                     /gene="pgsA"
                     /locus_tag="KRM55_001719"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBH1593968.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            complement(19804..21138)
                     /gene="rimO"
                     /locus_tag="KRM55_001720"
     CDS             complement(19804..21138)
                     /gene="rimO"
                     /locus_tag="KRM55_001720"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBH1593969.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            complement(21132..22190)
                     /gene="mnmH"
                     /locus_tag="KRM55_001721"
     CDS             complement(21132..22190)
                     /gene="mnmH"
                     /locus_tag="KRM55_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBH1593970.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            complement(22193..24604)
                     /locus_tag="KRM55_001722"
     CDS             complement(22193..24604)
                     /locus_tag="KRM55_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBH1593971.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            complement(24727..25461)
                     /locus_tag="KRM55_001723"
     CDS             complement(24727..25461)
                     /locus_tag="KRM55_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBH1593972.1"
                     /translation="MKDYREDNEKFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            complement(25574..26797)
                     /gene="dapG"
                     /locus_tag="KRM55_001724"
     CDS             complement(25574..26797)
                     /gene="dapG"
                     /locus_tag="KRM55_001724"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH1593973.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            complement(26807..27052)
                     /locus_tag="KRM55_001725"
     CDS             complement(26807..27052)
                     /locus_tag="KRM55_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH1593974.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGDILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            complement(27087..28334)
                     /locus_tag="KRM55_001726"
     CDS             complement(27087..28334)
                     /locus_tag="KRM55_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH1593975.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGI
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            complement(28492..29235)
                     /locus_tag="KRM55_001727"
     CDS             complement(28492..29235)
                     /locus_tag="KRM55_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1593976.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            complement(29501..31612)
                     /gene="pnp"
                     /locus_tag="KRM55_001728"
     CDS             complement(29501..31612)
                     /gene="pnp"
                     /locus_tag="KRM55_001728"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBH1593977.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            complement(31737..32582)
                     /locus_tag="KRM55_001729"
     CDS             complement(31737..32582)
                     /locus_tag="KRM55_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH1593978.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            complement(32822..33079)
                     /gene="rpsO"
                     /locus_tag="KRM55_001730"
     CDS             complement(32822..33079)
                     /gene="rpsO"
                     /locus_tag="KRM55_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBH1593979.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            complement(33183..34112)
                     /locus_tag="KRM55_001731"
     CDS             complement(33183..34112)
                     /locus_tag="KRM55_001731"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBH1593980.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            complement(34243..35148)
                     /gene="truB"
                     /locus_tag="KRM55_001732"
     CDS             complement(34243..35148)
                     /gene="truB"
                     /locus_tag="KRM55_001732"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBH1593981.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            complement(35161..35466)
                     /locus_tag="KRM55_001733"
                     /pseudo
     CDS             complement(35161..35466)
                     /locus_tag="KRM55_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            complement(35584..>36640)
                     /locus_tag="KRM55_001734"
     CDS             complement(35584..>36640)
                     /locus_tag="KRM55_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1593982.1"
                     /translation="INKTFGCCRFVYNKYLAKRIDVYKSDKETFTYKQCSSDLTNLKK
                     ELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKFKSKKINRFSYKTNFTNGNIMY
                     CGQYIKLPKLGMVKIRDKQVPQGRILNATISKEPSGRYYVSLCCTDVDIEVFENTNNH
                     IGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVAG
                     LQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQ
                     LEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINA
                     SINILKEGLRLITIQNK"
BASE COUNT        11554 a         6440 c         3983 g        14663 t
ORIGIN      
        1 aaaaatttag gagataaact ttatggaata cataattttc gatttggaat ttaaccaagg
       61 atttgataaa aaactcaata aaactgtatc caatgaaaag tgtccttttg aaattataca
      121 aataggagca attaaattgg attctaaatt caatataata gatacgttta atagttatgt
      181 aaaacctaca atttataaag acatacatcc ctttattagt cgtatgacta atattaaaaa
      241 ttctgatttt aatgattcgc ctactttccc tgaggtctac aacaatttta taaaatttat
      301 atcatcacaa gaccctatat tatgtgtttg gggagctgga gatttaaagg aattatacag
      361 gaatatcaac tatcacaagc taccatcaaa ttccttacct aaatcttata ttaatataca
      421 acaacatgca tctaaatatt tcaataatcc agcaggaaaa agcattggcc tacaaaatgc
      481 tatttctata ttagaacttg atgaaaaaat gtcttatcac aatgctttaa atgatgcata
      541 ttatactgct aaagttttta ttaagatata caatccaagt atagtcccag atatatatct
      601 ttatacaagt ataaaaccta aaactataag atattctaac aaaaaaagag ttgattatga
      661 taagttattt gatgaattta ggaaaatttt aaatcgtgaa ttaactaaag acgagaaaaa
      721 aatcattaac ttagcttata atatggggaa aacaaatcaa tttacattag aaaatgttaa
      781 gcaaagaaaa aacaaataga gtttatttag ataaaaaata ggcatgtaga ttaaaaaact
      841 agttaacttt aaatttatat ctacagccca atttttatca taattaattt ttattttatc
      901 tctaattcaa ctggacaatg gtctgaacct aatatttcag tgtgtatatc cgcacttact
      961 aatctatctt ctaatttttt ggatgcacaa aaataatcta ttctccaccc tgcattattt
     1021 tttcttgcat taaatctata tgaccaccaa ctataaacac cttctttatc aggattaaaa
     1081 tatctatatg tgtctataaa cccactgtct aataatttag aaaacttctc tctttcttct
     1141 ttagtaaaac ctgcattttt catattattt ttaggatttt ttaaatctat ttctttatgt
     1201 gcaacgttca tatctccaca cacaattaca ggcttatgat tatctagttt ggttaaataa
     1261 tctataaagt cgtcttccca tctagttcta tattctagtc tctttaattc agattgagaa
     1321 tttggcgtat atactgtaac aaagtaaaaa tcttcaaact ctagagttat cactctaccc
     1381 tctttgtcat gttcttctat atttattcca tacattactt ttaaaggctc tttttttgta
     1441 aatatagcag tacctgaata accctttctc tcagcataat tccaatattg aaaatatcct
     1501 ggtaaatcta actctatttg cccttcttgc aatttagttt cttgtaaaca aaatatatct
     1561 gcatctactt ctttgaaaaa gtctaaaaat cctttcccaa cacaagctct tattccatta
     1621 acattccatg atataaattt catacttata ctcctcatct aaacattgac acactcccca
     1681 tagctaaaga tgggggcttt tcaacaattt tattgtaaat tcttaattca cttttatttt
     1741 aacaatgcta tactataatt tcatctaaaa ttactattta cttaatacct aaaaatatat
     1801 gttttaatca atttttaact tttttgttaa atcttcaggg ctcattgaag aaacatacat
     1861 atttgttcca agttcaaatc ctccaaaatt atattttctt gggattatgt gcatatgaac
     1921 attaaaatac gattttgttt caatctttgt tggatgagtg tgaatacata aattaaatgg
     1981 catatatcca ttgatattat ataacttctt aaacaacttt tcaaatattg tagaaagctc
     2041 ctgtatatta ttatcattta actcaccaaa ctctatttta tctttaaata ttattcttac
     2101 ttctccacta tacttggttg catatggtat aagtaccaaa aaagcttctc cattataaac
     2161 aactcttcta tctaaactta tttcattttc tattaaatca tcatacaaag agcttttatt
     2221 gctgtcataa tactcctttg aaaccaacag ttcattcgta atttcaggtg gaataaaaga
     2281 catagacaat atttgagcat gtggatgcat caaagatgct cctgcctttc tcaagaagtt
     2341 tttgaagata ctaacatact ctactttatc atctttcgac aaatctctaa atctatttct
     2401 atacataaaa aaaacatctt caaattcttt ttgactcatg ttataaaaac tacgattatg
     2461 tttatcgctc tctatcatta cttcatgaac accatataca tctcttgcca tatcatcaat
     2521 tataggaaat ttattgtaga cagattttac aagccatcct tcttcacttt ctatttcaaa
     2581 taatgcatca gttgcatgag cttcatttcc tttgcaaaat gggcattctt catcatattc
     2641 attagtttct tcatcttcat ttgggatatc tgctgtatct aaaggtcttt ttaacctatc
     2701 tgtagcaaat ataacaacat cattggtaat tggatctatt cttaattctt tcataattaa
     2761 cacctcttag ttaatagcct ttaatataat tatatgatat ttatcgtatc tgttaaataa
     2821 atttataata ttttttataa ttttgcatat ttattattat atattttgtc tatagctgaa
     2881 agattataac taaaaaatca ctatcagtat atcagaatat tatcttacta taaattaatt
     2941 tatgaataca taatttagtg gcataaacat gggtatttta ctataatttg ttaaaagttt
     3001 attttaaagc tatattaatt ttttttgatg atttttaccc ataagtatgt tattattatc
     3061 ttgtaaagat gtcttgtatt caaacataca atttacataa tacaatatac gtatttaaat
     3121 taaatagggg gtattaaaat gaattattca aacagagtta gtgcaatgca agcctctcca
     3181 atcagaaaac ttgttccatt tgcacaagca gcaaaagata aaggaatcaa agtatatcac
     3241 ttaaacatag gacaaccaga cataaaaact cctaaaggat tttttgatgc tgttaaaaac
     3301 tttgatagcg aagtcttaga atatgctaca tcagaaggta ttccagaatt attagaagca
     3361 cttcaaaatt actataaaac ttacgatatg aattttgaaa aagatgaatt attagtaact
     3421 aatggtggta gtgaagcttt acttttcact atgatggcag tttgtgaccc aggagataat
     3481 ctattagttc cagaaccatt ctatacaaac tacaatggat ttggtcaatc tgtaaacgta
     3541 gaagttaatg ctgttacaac aaaggcagaa aacggtttcc accttccatc taaagaagaa
     3601 atattgtcta aagtagatga taaaactaag gctataattc tttctaaccc aggaaatcca
     3661 actggtgcaa tttatacaaa agaagaactt aatatcctag ctgaaatagc taaagaaaaa
     3721 gatttatgga taatagcaga tgaagtttat agagaatttg tttatgatgg gcttgagtat
     3781 acaagctgtg gtaacttaga gggtgtacag gatagagtta taataataga cagtgtttct
     3841 aagagataca gtgcttgtgg tgctagaatt ggttctatcg cttgcaaaaa taaaggtctt
     3901 atcgctcaaa tccttaaatt atgtcaagga agactttgtg ttcctacatt agagcaaata
     3961 ggagctgttg agttatacaa aactcctgtt tcttacttca aagaagttaa tgaagagtac
     4021 aaaaaaagaa gagatgtatt atacaatgaa ttaatgaagg ttgaaggtgt tatatgtaaa
     4081 aaaccaactg gtgctttcta tatagttgct aaattaccag ttgaaaatgc agaagatttc
     4141 acaatttgga tgttaaaaga atttaacaaa gataatgaaa cagttatggt ttgccctgct
     4201 gaaggattct atgctactcc aggtttagga cgtgatgaaa taagattagc ttacatctta
     4261 aatgaaaaag accttcatag agctgctaca ttattaaaag aaggtttaga gcaatatgta
     4321 gctttacaaa aataattttt taaacttaat ttatataaat ttaatgatat aaaatgtccc
     4381 cttttcagat attatttgaa aaggggacat ttcttaatta atatattaat taagacttag
     4441 acctgactat ttttcatttt ctttatatag tgttggccag taatctttat tcactttaat
     4501 taaagcatct aaaacttgtc ttgccttagt tggagagatt atagttctat ttaatgttaa
     4561 agataaaata gctttttcat aagattgttc aaagtatgca tcaactgcta acttttcata
     4621 agctagttga ccttctaaca gtcccttata aaatgttggt atattaccta catgtaaagg
     4681 tctcggtcca ttctttgtaa gaatcgcagc tacttctacc attgcatcat caggtaagtt
     4741 gctaatagcc ccattatttt ctgttataac tatggctatt tggtgtttgt tatgagctat
     4801 tgcttctgca acttcaacta taaattcccc atgagcatca ttatgcacta aattagaacc
     4861 tatagatgtt cctttttcta taacagattt acattcttca aatacacgct tttctcttcc
     4921 attcataact tctcttgctc tagtacaatt tatatttgat ttagctactt ttttatcagg
     4981 atatagataa tactgtacat atgtattagg taagtaatct ggtacatctt ccaacatatc
     5041 tttaaccatt ccataagtgt ctaaccaaga tttatctctt tgttctgcat caacaggttg
     5101 gaatccagag tttgctacta aatcttttat cttaggtacc aaatcttcac catttttatc
     5161 atacaaatgt gtaaaccatc caaagtgatt taatccaaag tatacaggct caaatgttct
     5221 tgaatccatg tctaacaatc ttccataaga ccttaacaag ttaactggtt ggtcacacat
     5281 attaagtaat cttttatcat ctggaaatac tctttttaat gcttctgcaa caatagcagc
     5341 aggatttgta taatttaata tccatgcttt aggagagtat tttcttacag tcttaaccat
     5401 ttctatcata tcacctatag accttaaccc ataagcaaat ccaccagctc cacaagtttc
     5461 ttgaccaacc agtccaaatt gtagaggaat cttttcatct aattctcgca tcttaagacc
     5521 accagttctc atttgaacaa atacaaaatc tacatctata aatgcttcat ctgggtttgt
     5581 agtatattca agtgttgctt taggatattc ttctttaaat aatatttttc caaattcccc
     5641 tattaatctt tgacgttctt ctactacatc taacatagtt actttattta gaggaaatct
     5701 atcactcatt ttacataaag actttaaaag tcctggagtc caagtactgc ctcctccaac
     5761 tatagctata ttgtatcttt ttttcattgt catattaatc acccctgttt tttattaact
     5821 aacttgtaag atgattataa tatataaagt tttctacatg aatactttta ggtaatcatt
     5881 aaaaatagtt caattttagt atttttttca aaattgtaat ttttttcatc tattgtattt
     5941 ttcaatgtat ttatgaaaca tatattccat aagagaaagt gctggcactc tagatgtata
     6001 gttaacacta ttaaaattat attgtggaga agatacaaat aattttatat cagctatatt
     6061 tgataatgaa ttgacactta tatttgtcag agaaattact ttaacttgat ttgtttttgc
     6121 tatattacat gccttaataa cttgagcagt ctctccagac atagatacag caattacaag
     6181 gtcatcttta gtaatatttg atgcagccaa atacatgaga gttgaatcat catagtattt
     6241 tacatttaca cctatagctg aaaaacgttg agacatttca gtacatacta atctagaaga
     6301 cccaacacca aaaaaatata tatgcttaga attatgtatt tcatttaaac acatatctat
     6361 attctctaca tttattaaat tttgtgtatc cataacatca gtaaaaatat cactttgact
     6421 tttagtaaac tccttatttc tttcatttct atttgaatat gaaaaaacta aaaagttttt
     6481 aaattcacta tatccagaaa agccgagctt ctgacaaaac cttactatgt atgcagtcga
     6541 attaaaagtt tcatttgcta tatctttaat ctttttttga tttatttttt cagaattttt
     6601 tagaaaatag tttaaaagag atatttcatt tgtagataat tttttttgat ttatatctaa
     6661 tttgtctatt aggttcattt atacctccat aataatgatt tgtagttaaa caactttctc
     6721 atatttatta tataaatata cactatacag catttatctt atgtttatta tactataaaa
     6781 aagacaatac aaattataaa ttagtattgc cttttaatat ttactttaaa tagacattgc
     6841 aaaagaaact tcgtctctta cttgagatac agatggccca taaattattt ggatatcttt
     6901 atcagatact tttataactc ccattgcacc tgtatatttt ttaaaagcat tttcatctac
     6961 tttactcata tctttaacta ctactcttaa gcgagttata cagtttgtta tatcttctat
     7021 attgtcctta ccacctaaat atttaattat agataatgct ctcttagtag tttctccact
     7081 ttgagctatt tctactttat ttgataaagg ttttaaatca aaatttatat ctgttatttc
     7141 ttctcgtcct ggagtttgta agttaaatct aagtatcaaa atcttaaata cattataata
     7201 aactattgca tacactaaac caagtattat agaataaatc cactttgtat ttggttgcat
     7261 aactccaaat actactaaat ctattatgcc accttgagta tttcctattg ctactccaaa
     7321 tatatgcatc atcataaatg atatacctga taaaaatgca tgtataacaa ataatattgg
     7381 tgatacaaat aagaatgaaa attccaatgg ttccgtaatt cctgttacaa atgttgctaa
     7441 agcaccagct agtaatatac ctttaacctt cgacctattt tcaggctttg cagttttata
     7501 catggcatat gcagcagcag gaagaccaaa taccattata ggtattttcc cttgagctaa
     7561 aaatctagtt gcttctgttg aaaaactgat tgtttcaggg tcacttagtt gagctaagaa
     7621 tatgttcaat gctccaaata cttcttgccc tcccacaact aaagaacctc ctacttcagt
     7681 aaatctaaac atagcattta atatatgatg taatccaaat ggtattaaaa gtctttcaag
     7741 aaatccaaat acaaatgttc ctaaatatcc taaactagct ataccaatac ctacactctg
     7801 aataattgta tttacatatg gccatatata tggtattatt atccccaaaa tagagaatac
     7861 tactgttgtt attattggaa caaacctagt tccaccaaag aatcctaaat aatctggcag
     7921 ttttatatta tagtatttat tatgtaatga tgctgttatt ataccaacta caattccacc
     7981 aaatactcct aattctaatg tttgtatgcc taaagttaca gcttgaccca tttctctcat
     8041 catgtcaggt tcagcaagaa tccccctaca ccctaacata taatttacac tagtgtgtaa
     8101 tactaaataa ccaacaaaac cagaaaatgc agaaactgct ttttcttctt tagcaagacc
     8161 aacagatatt gatatagcaa agaatattgc taagtttcca aaaagtactc ctgttatagc
     8221 ttttgtaaaa cccaatattc cttgaataaa attatttgct aaaaaaggca tatcactaac
     8281 tatattagga tttgaaaatg ctgaacttat tcctaaaaat atacctgctg cagatattaa
     8341 tgctattggc aataaaaatg attttcctaa ctgtaaaaag aaccctttca ttttttgttt
     8401 catttctatc cctccatttt taaattttta aaacgttttc tatgtcataa ttatatattt
     8461 ttattttgtt tttgaaactt tataatttgt tttaaaatat ttttacataa atagtaattt
     8521 tttcaaaact gtaaattttt tcaaacaaag acatagtaac gttgtaacat atataaattt
     8581 aaaaagagct tagaaaataa aattattgaa tataaaatgg aaaaatataa attacacaaa
     8641 gagatatgag tacgtactaa caaatacgaa aatgtataag aaattataaa aaagtacatc
     8701 aagaaaattt aagatgtact ttttagattg tatttagact tataattata tagttaaatg
     8761 aataacaaag aattaatctt agtactatta aatacaaaaa tttttatatt ttttctatct
     8821 aaattcttct ttgtttaata tatattgaag agtatttatt gcttctaaat atttttttct
     8881 gtcttcttca gttaatttag aaagtttttc tcctaaacca tcacttaatt tatccataaa
     8941 atcagttgct atcttatctc cctcttcagt aatgtcaatt agatattttc ttctatcaac
     9001 taaatctctt ttccttgtta catacttctt atcagttaaa tcatcaacca tactagttaa
     9061 actgcctttt tctatattta acttagagca taaatcagtc atacttatta ctccataatt
     9121 ttttatgaaa actaatgctc ttaattgtgt tttatttaca ttataatctg gtgcaaattt
     9181 ttttaggtct tctaagtaca ggctagaata aatcttagga aatgttttta ctaaaaaact
     9241 tatggtatct tttactatat agttcatata atcacctcgg ttgttttaaa atttattaaa
     9301 ttatctaaat aactttattt cagtttacat taaaaatatt gcaagtacaa tagtttttgc
     9361 tgaatgttta aatttaatta gtaatcttat cattttttta tttttattta tattattcct
     9421 attaaatatt atttatatag ctattttatt aaattcatgg tatagtaagt aaagaagaac
     9481 tcttcacagc ggtggagaga agacgctagc ccattaaaat ggctatctta tttataaata
     9541 agatagccgt ttttaattat attttatctg tacaattcta tactcttaag tctacatcta
     9601 cttttcctaa gtcttcctta taatctttta tagcaggttc tacaacttca tttacaaatt
     9661 ctacaacttg ttctggagct ctacctataa agttttttgg gtccattata gatagtattt
     9721 cttccttgct cattttaaat gaatcatcat tcattataag ttcaattaag ttattatcct
     9781 tgccttcatg ctttactcta taggcagctt tcatagaata ttctcttatt atttcatgta
     9841 attcctgtct atctccacct ctttttacag cttccataag tattgtttct gtagccataa
     9901 aaggaagttc ttcatttaca cgtctattta tcatattttc atatactact aaaccatcag
     9961 ttacatttat ccctatttca agtatagcat ctgctgccat aaatgcttga ggtattgcca
    10021 atctcttatt ggctgagtca tctaatgttc tctctaacca ttgagtggct tgtaccattg
    10081 cagggcttat agattcagag attatatact tagataaaga tgctattctc tcacttctca
    10141 ttggattcct cttataagcc attgctgatg aacctatttg atttttttca aatggctctt
    10201 ctaattcttt taaactttgt aaaagtctta tatcattagt catcttatgc atactttgag
    10261 ctatccctga tagtatgctt attacttgat aatctaactt tctagtatat gtctgtccac
    10321 ttactgcata ggaagaatgg tatcccatct ttttacaaat tttcttatct aactctttta
    10381 ctttttcgtg gtctccttca aataagctta aaaaacttgc ttgagtacca gtagtacctt
    10441 taactcctct taacttcatg ttgtctattc tatagtttaa atcttccaaa tcaagaatta
    10501 aatcttgagc ccataaacaa gctctttttc ctactgttgt aagttgagca gcttggaagt
    10561 gtgtaaatcc aagagctggc atatctttgt acttaagtgc aaattctttt aaattgttta
    10621 ttaaatttac aagctttact cttagaagtt ttaaagcttc attcatttgt ataacatctg
    10681 tattatctcc aacatatgca gatgttgctc ctaaatgtat tattcctttg gctttttcac
    10741 attgtaaacc ataagctttt acgtgagaca ttacatcatg tcttacttct ttttctattt
    10801 ttctagcttc atcaaaattt atattatcta tattagctct tagctcatct aattgttctt
    10861 cagttatatt gattcctaac tcatgttcac cttctgcaag tgcaacccat aaccttctcc
    10921 atgtagagaa tttaaattgt ggagaaaata tataactcat gtccttgcta caatatctgt
    10981 ctgtaagtgg gtttgagtaa gtagtatatt tattatctat cattatatta gcaccttcct
    11041 taaatctttt gtcgtgtgat tactgtgtac acattagtac ataaataatt atatataatt
    11101 ttacgaacta taacaagact tttttatttt ttgttcacat ttatatatag tattttttat
    11161 ttattactat tttttattta tatccaaatt atctttttca attaagtaat ccactatttc
    11221 actatcaaca aaatttaata catacttata tctaattgca tagtatttat cactccatcc
    11281 aagctgattt tttacatcac tttcatctgc cccaagcctt aaacttattg ctgcaaatga
    11341 atgtctaaaa tctcttgctg aatattgaga aagtccagct aaatctaatg cttttttgac
    11401 tataagtctg acatttctat ctgttataga attactcttt tgagttgtaa aaataaaatc
    11461 atcactaggt attattacct ctggaagccc agaataattc ctgtaatctt ctaaaagttt
    11521 aaaaaagtat ggatgtaatt taactactct ttcttttctt cccttaccta accttacata
    11581 tgagttatcg ttttcatcta ccataaggtc tttccacttt aagctaacta attcatttaa
    11641 taaacaccca gtagtaacta gacagactat tattactcta tctcttatat ttaattttgg
    11701 taggatacct ataagtttat ttatttcttg tatacttaga acatcatctt ttgtttttat
    11761 tcttgttact gtgggttttt ctacatatct aaatggattt atatctatgt atccttcttt
    11821 ttttaagaag ttataaaaac tatgtaaata actatatatc ttttcacaag ttgatttcgc
    11881 atatttagtc tgtatatagt ctacaaaatt tttacaatct tctttcgtag cataaatcaa
    11941 ttctttccct tttaaaaatt ctttaaacag tataaccttt gataaataat cgtgtttcgt
    12001 gtttggattt aattttgtag aaaaaacatt aaaagtttca tactcataat catctagtat
    12061 ttttgtacta tacataataa ctcctttcct tttcataaaa taaaatagct atacttttac
    12121 tataccatat atttccccct caaatatacc ccttattcaa tagataactt ttaagtttat
    12181 tttgttatat tgtgaaggtt ttatgaaaat atcaatcttc cattgtgcac tacacagtac
    12241 tatggtatta taagttagta aaaggtggca tttttttatt aatctatgaa taaaatatgc
    12301 tactataaat ttgtattgga ggtattttga tttggaaaca tttagtttgc ttgaaatttt
    12361 taaggcagtc attttgggca tagttcaggg aataacagaa tggctaccag taagtagtac
    12421 agggcatatg atattagttg atgagtttat aaaattgaat ttttcaaata catttataag
    12481 tacattttta gttgtaattc aatttggttc aatattagct gtacttgtta tattttttag
    12541 aaaattaaat ccttttgata gcgcaaagaa tattaagcag aaaaaagaaa cagtccgttt
    12601 atggcttaag gttataattg cagttatacc atctggagtt attggaatac tgtttgaaga
    12661 tgatatagat agattattct ttaattcaac agtagttgct attgctctta ttgtatatgg
    12721 tataataatg atatggcttg aaaagagaaa taaaaaacct aagtataaag atttttctca
    12781 agttacatat aaattagctc tttgtatagg attattccag tgtctagctc ttataccagg
    12841 tacatctagg tctggttcta ctataatagg tgcagtatta cttggtactt ctagatatgt
    12901 agcagcagag ttttcattct tcttagccat ccctacaatg cttggagcta gtgcattaaa
    12961 acttctaaaa gctggatttg gatttactgg atttgaatgg cttattttag gtgttggttc
    13021 tgtagtagca tttgttgttt caattgtagt tattaaattt tttatggact atatcaaaaa
    13081 acatgacttc aaagtatttg gttattatag aatagtcttg ggtatagtgg ttcttgctta
    13141 tttctttcta ttataatgta ttctaattta ataacaaatg ataaggagaa aagttatgag
    13201 tgttaaaaaa gaaatatttg attggattaa gtcaatagct atggctattg tacttgcatt
    13261 tgtaattcta caatttataa gaccttctat tgtaagtgga gaatcaatgt atcctacttt
    13321 agatgataaa gattatctga ttttaaatag gatatcatac aaggttggta aacctgaaaa
    13381 aggcgatatt gtagttttta aaaccaattt agttgatgga gaaacaggaa agaaaaaaga
    13441 cttaataaaa agagttatag ctactgaagg tgacagaata aaaatatcaa attctaaagt
    13501 gtatgtaaat ggaaaattat taaatgaacc atatatacac aataactata cttctggaga
    13561 tatagatact gttgttccaa aaggtaaact atttgcaatg ggagataata gagaaaatag
    13621 taatgatagt agattccctg atgtaggtat ggttgatgaa gatgaagttc ttggtaaggt
    13681 tatggtgaga ctattacctc ttgataatat tgggaaagta gactaaaaaa taagagactg
    13741 aattggtaaa gtttatttta caaatctcag tctcttttta ttttcttaaa ttacaaatat
    13801 ttttttacta aatatctttt gattctgtaa taagtcttat tatatcactt gcttcttcat
    13861 taaaagttgt tactatactt aggtagtctg ttgctctact catagctaaa taaaccttat
    13921 ttaaatctcc tacaaagtca tttacttgat aatcttgttc aatatcattt atagtttgat
    13981 tgtataacat ctctaattca catactatta ccgctttata ctctaaattc tttattgcat
    14041 atatatttgc tattgtagtt cctaccttct tacttatatt tgtcaaatta tcttctgcac
    14101 atatataagg aatttttgcc tcttccaatg ctttttttaa catatattga aagtaaatgg
    14161 tttttccact ttttaatttc ttcttattgt aaggataaac gatagcaact tcagaataat
    14221 caagaccttt tttacttatt aaatactcaa tttcccagat tacagaactt atttggtcat
    14281 caaggtcact tacttttatt atatcaacag acttatttcc acctctaagt gctttagtat
    14341 aaaagaaagt actaaattct gtatttggtc ttaattcgtt gatatatgag ttagaattat
    14401 ttgaaaattt atttgtaaaa tctacaatct ctttagcttg tctataattt ttacttaaga
    14461 taatcttatc atcaaattct ataccattat ataatttttt aaatatattc aatctattag
    14521 agatattcaa ggagttacaa gaacacacat taaatatgaa ttttgtttta tataaaaact
    14581 cccttataaa atctatttca tactctaaaa agctttctgc ttcatcaata aaaatagcct
    14641 tgaacatatt tttatttttt ataatgttct gtgcttgttt tacaagatta ttaaaggtct
    14701 tttcgtaatc attttttaac atgttataat ctacaattaa attgaatttt ttagctagtt
    14761 taaatataaa agaactaaat gtgtgaactt ctaaattgtt attatctttg tataataact
    14821 ctatcctctc tcgaagctca ttgcacaatt gttttgtatg tgtaaatatg actaatttat
    14881 gatgtggata tacttttgct aattttatag ccctagaaag cataattgct gttttgccta
    14941 taccagaacc accttcaata agtgtattcc catatttaat agaaacaaca tctttaattt
    15001 gaacgtcttc catcatagtt gctgtatact tatagtcatc attgtagaat gaaatttttt
    15061 taaatttttc atttagatga agtttatcat ttattatata gtattctgaa catatgtcta
    15121 gtaaaaataa atttaagttt atttcatcat tctcatcatt aagatattcc tccagcgaac
    15181 ccttattcat tatatcttga agcttatttt tatctattat attattatta acaaattctt
    15241 caaattcata tgtttcctca acttcaacgt atggcataat gtaaacgtag ttataactta
    15301 tatttctatt cttttgtccc atttttagtt tcaaaagttc atattcctca ttcataactt
    15361 caagtaactc ttcttctaaa ataaaaaata tatcttctgt tgtatccata aattttataa
    15421 ataaaattct tccatcttta acatacaaca aatcggtatt tattccttta aaaggagtaa
    15481 cttttggcac tactttaacg tcctcattga tattttcgta aaatattttc tcgaactcct
    15541 tcaattttag ggcgtctaac tgagaattta tatttatgta ttggctcact tacattacct
    15601 ccttctgtta tacttaatta taccattttg aactatattt ttatatatac tttttatagg
    15661 caaatttagt aaataaattc aaaataaata caaataaata caaaactgct aaaaaaattt
    15721 tgcaataagt atagatattt attgttataa aatactttct gtaaataata aaatgataaa
    15781 tttcataatt aatgcttaaa ataataagta aagtcttaaa aaaaataaat cttgttagcc
    15841 aaaaataaga tttattataa aaaatttaaa aacctactaa aaataatcta ttttcattag
    15901 caggttttat ttataatctt cttatattaa tactattata tcctattttt agattttact
    15961 gtagtattta ctatttattt tgtagtaaag tattgatttt acaacttcat tatatcaaac
    16021 aaacttggat aattatataa ataatacata tataaagctt tattttatta atcttttgta
    16081 agtagcactt ttagcactta gattattttt gcattatata aaattaaact taaacaattt
    16141 aaaagccaca agatatatta tcatatcttg tggcaaattt aaatttctaa aaatattttc
    16201 ttattattta gatattattt cttttacttc gcatactcta tagctcttgt ttctcttatt
    16261 atgcttactt ttatttgtcc aggatattca agttcatcct ctattttctt agtcatatct
    16321 ctagccaata gatgtatttc ttcatcattt atagcttctg gttttaccat tattcttatt
    16381 tctctaccag cttgtatagc aaatgatttt tctacacctt catatgaatt agctatttct
    16441 tctaattttt caagtctctt tatatatgct tctaaagttt ctcttctcgc accaggtcta
    16501 gcagctgata ttgcatctgc tgctgtaact aatacagcct ctactgtttg aggctcgtaa
    16561 tctccatgat gagtactcat ggcatgtata acttctttag actctttata acgtctaagt
    16621 aaatccatac ctatttcaac atgtgtacct tccatttcat ggtctacagc cttacctata
    16681 tcatgtaata aacctgccct cttagccaat ctaatatctg ctcctatttc agcagccatt
    16741 ataccagcta tatgagcaac ttctatagaa tgtttaagta cattttgtcc ataactagtt
    16801 ctatagttaa gtctacctaa taatcttatt aattccggat gaatcccatg tacactagtt
    16861 tcaaatgcag cttgttcacc atattctttt ataatattgt caacttcttt tctcgccttt
    16921 tcaaccattt cttcaattct agctggatgt attcttccat ctgctattaa tttttctaga
    16981 gcaattcttg caatttctct tcttattgga tcaaatcctg ataaaattac ggcttctgga
    17041 gtgtcatcta ttataaggtc tatacctgtt aaggtttcta aagtccttat atttctacct
    17101 tccctaccta ttattctacc tttcatttca tcattaggca agcttactac tgttacagta
    17161 gtttcggcta cgtgatctgc tgcacatttt tgaattgcat atcctataat ttctcttgat
    17221 ttcttatcag cttcttcttt agcttgactt tctatctctt ttatcattat agacatttca
    17281 cgtcttacat ctctctccgc attggttaag atgatttctt tggccttatc agaagtaatt
    17341 cctgatatac tttctaattt ttctaactgt tgagttttta ttacttcaac ttcttcttct
    17401 ttcttttcca ctacctttaa tttttcactt aggtttactt ctttagattc taaattttgt
    17461 aattttctat ctaagacttc ttctttttgt actactcttt tttcatactt ttgtacttct
    17521 gttcttcttt ctctgttttc tctttcagct tctgttctcc acttatggat ctcttcttta
    17581 gcttctagta atttttcttt ttgtactgtt tctgagtcgt ggtgtgcttt atctattatt
    17641 tctttggcca agttttcagc ttgtccaatt tttgcttcag atatattttt tctaacaaaa
    17701 tatccagcta taataccaac agctgcacct attacaatca ttactacact atctatgaca
    17761 tccacctcct tcgttaataa tcccaaaatg tcatcactat gattaaaaaa tattcctaat
    17821 aattaaaatt aaatttagat attttatcct cacttaattt tataattttt tcaacattgt
    17881 gtcaagctaa tagggagcgt ggcatgtctt taattactag ttattttttt gtatttttac
    17941 ttattcttct acaatttctt ttgatactga aatacctgat tcttcatgtt cttcatttaa
    18001 attgtaaaat gctctaactt tctcatctat ttcagtagtt aaatctaaat tatcttccaa
    18061 gaatttttta acattttctc ttccttgtcc aagtttagta tcattgtaac tataccatga
    18121 acctgatttt ttaactatat ctacatcagc agctatatct aaaaggtctc caatttttga
    18181 aattccttct ccatacatta tatcaaattc agcttgctta aatggtggtg ctactttgtt
    18241 tttaacaact ttaactctag ttctactacc tataacttta tcaccttgtt ttattgtatc
    18301 tatttttcta acatccaatc taactgatga atagaatttt agtgcacgtc ctccagtagt
    18361 agtttccggg tttccaaaca ttattcctac tttctctctt aactggttta taaatatagc
    18421 aacacaattt gattttttaa ttgaaccagt taactttcta agtgcttgtg acataagtct
    18481 agcttgtaaa cctacatgag aatcacccat atctccatct atttcagcct ttggaactaa
    18541 tgctgctact gagtctatta ctattatatc tatcgctcca cttcttatca atgcctctgc
    18601 tatctctaaa gcctgttcac ctgtatctgg ttgagatatt attaggttat caacatccac
    18661 acccaaagct tttgcatata ctgggtcaag tgcatgttct gcatctataa atgcagctat
    18721 tcctccatct ttttgagctg atgctacaca actaagcgca acagtagttt taccagaaga
    18781 ttctggacca tatacttcaa ctattctccc tctaggtaga cctcctatac caatagctat
    18841 gtctaaacca atcgctcctg ttgatataac atctatagac atagatgttg cttctcccaa
    18901 tttcattact gaacctttac caaaatcttt ttcaatttta cctaaagctt cattcaacgc
    18961 ttttaatttt tcttgatcta cactcatctc tataccatcc cttcatttat ctacaaacat
    19021 ttgttctctt gttatatatt aattatataa cataaatcaa acctagtcaa tttaaaaacg
    19081 ctactaatga ttatattttt attcattaca ttttatttat aaaccattat taataattat
    19141 atacacaaaa gaaaatattc ttaaaatgaa aagaggtata ctataatagt ataccctttt
    19201 ttacattttt aaaattttaa gttgttattt tttatttatt aatcattagt ttttatttat
    19261 taaagcataa ttttttactt agaagacata aaaagctctt tatttttata tagatattcc
    19321 catccagaat ataatgtaag tagtgtagct ataagaatga gaatttcacc aatatttaat
    19381 atcaatacat tttcaaactg agcacctaac aataaaaaca ctatagatac catttgagtt
    19441 atcgttttaa gttttccact gtttccagca gcaattactt ttccatcagc agcagctata
    19501 gctcttaata tgctaactgt aagctctcta gccactatta taattaccat ccaactactt
    19561 acaagatggt cttctatcat acatgtaagt gctgaaataa ccaataactt atctgctaat
    19621 gggtccataa attttccaaa gtcagtgact agattgtatt ttctagctat ttttccatct
    19681 aaagcatcag taattgaagc tattataaaa ataatacaag ctattaaaaa tttatttggt
    19741 acattgagca acataattaa aacaaatact ggtattaaaa atattctaaa caaagttaac
    19801 ttgttaggca agttcatata aaacatctcc cattaaatcg tattccattg catcatttat
    19861 ttgaacactt acaaattctc ctacttcaag attgtctaca ctttttacat acactatact
    19921 gtcaatttct tctgcatcac cttgtgttct tcctgtatat acattatctt ctatctgttc
    19981 ttctattaac acctcataag tttttcctat ctttttgtca ttaagttctt cagatatttt
    20041 ttgttgaatc atcattaaag tatctcttct ttgtattttt acttcttcat ctatatggtt
    20101 tggcaatcta tctgctggtg tatcttcttc tcttgaatat gcaaatgcac caagtctatc
    20161 aaatttaacc tcttcaacaa agtccacaag ttgtttgaag tcatcttctg tttcaccagg
    20221 aaaccctact attattgtag ttctaagtat agcatctggt atattacttc ttatcagatt
    20281 gattttattt aatatatctt ctttagtagt ttttctattc attaatttta aaatattgtt
    20341 acttgcatgc tgtattggca tatcaaagta actacatata ttatcatatt tctttataac
    20401 ttgtatcaat tcttctgtta tagattctgg atatgaatac ataaccctta tccacttaaa
    20461 tccatctatt tttgcaagtt cttctaaaag ttctgataat ctttcttttc catataaatc
    20521 aaaaccatac tttgtcgtat cctgtgctat aaccacaagt tcttttactc cagattcagc
    20581 taatttctta gcttctttaa ttatatcttc aaattttcta cttctatatt tacctcttag
    20641 ttttggtatt atacaataag tacaattatt ggaacatcct tctccaattt ttaaataggc
    20701 catatagcta ggtgtagata tatatcttgg taaatcttca ttaaatacaa actctatatc
    20761 attaaggctt acaatttgat gcatttcact taattcttta agtattttat ctatattttg
    20821 atagcttcct gttcctacta tagcatctat ttcaggaatt tcagttttta attcttcaga
    20881 atatctttgg gctagacacc ctgttactat caacaacttc aaattgccag ttttttttaa
    20941 ctctgcaaag tttattatcg tatctataga ttcttgttta gctgactcta taaacccaca
    21001 tgtatttact ataattacat cagcttcttc aaaatctcca attaatttat agcctttgtt
    21061 atttaaaatt cccatcatta tttctgcatc tactaaattt tttgagcatc ctaatgattc
    21121 caatgctatt tttaacattc actttctcct tccaatatac tctcatataa gtctataaca
    21181 tcttctaaag ctttttgtgt atcattaaaa tttataatct tactatactt atatttctct
    21241 actgaatgca tataaagtgg gtcgtagtat tctaaaagat atctttttac aagttcttta
    21301 tattcacctg attctaataa atcaatataa tcatctacta ctttattacc caatcttttt
    21361 ctaaacttgt ttatacattc ttttaaaatc aatatattac cttcatcttt atcataaata
    21421 taatctctac aaagtctatc aactctattt tcaatatcac attctaataa tatatgatgt
    21481 ccttctcgtg tcattgcctc gaaaatttca tttggaactg taacacttcc aactcgtttg
    21541 ctttcactct cgacaaatat ataattctct ttcgaaaaaa atatactttc aaatagtttt
    21601 gtttcaaagt tcttttgaga tggtggcttt ttatcaaaag ttataaaacc aaaggtagaa
    21661 ccactgtttt tagctatgcc ttctaaatcc agcacgtcta ttcctttttc atctaataaa
    21721 tgtaacaaat cagtctttcc tgtaccagtc aatccatgaa cagatacaaa gttttttgta
    21781 tccattacat gccttaaata ctctaaaaca aaatttctat aagccttata tccaccttca
    21841 agttgatata catttacacc taatgatgat aataaattta ctatactgcc acttctcatt
    21901 ccgcctcttg cacaatatat gacaatatta tcataattta atgcaagttc tgctgcttgt
    21961 aaatatatat cctttaattt atacgataca tagtcaaatc ctttttgtat tgcttcatgt
    22021 tttccctgca tcttataaat tgttccaact tcattatgtt cattattttt aaaaagaggc
    22081 atattgattg cattcaatat atggtcttct tcatattctc cttcagttct cacatctaca
    22141 aatattactt tatctagctt aagtgctttt tctattttta taactgacaa ttctattcac
    22201 cttctaaatt ctgcaaatcc tgtttgctta ttaatacctt tctcggttta cttccctcac
    22261 ttgctccaat tattcctctt tcttccatag aatctataag tctagctgct ctattgaatc
    22321 ctattttaaa tcttctctgt agcatagagg cagatgcttg accactttcc acgacaaatt
    22381 ctatcgcttc actcaaaaac tcatcctcat cactaccctt tgaagtatta accttagata
    22441 tagtttcaat tatatcttct tcatatttta ttccatcttt aacctgactt tttacaaaat
    22501 cgattacttt ttccgactca ctctctgata tgaatgcccc ttgaagtcta actggttttg
    22561 ctgcaccaag tggatagaat aacatatcac ctttacctag aagcttctct gcaccaccca
    22621 tatcaaggat tgttcttgaa tcagtttgag atgatactgc aaatgctatt ctagatggta
    22681 tattagcctt tattacccct gttataacgt caacagatgg tctttgagtt gctacaatca
    22741 agtgcattcc agcagctctt gccatttgag ctaatctaca aatataatct tctacatcat
    22801 ttgcacttgc catcattaaa tctgctaact catctattat tattactatt ttaggaagtt
    22861 tttcttccgc tttctcatta taacttgtta catcttttac ttgagcatct gcaaataatt
    22921 tgtaccttct attcatctct gtaactgccc aatttaaagc atttgcagct tttttagggt
    22981 cagtaactac tggtatcaat agatgtggta ttccattata atttgcaagt tcaactactt
    23041 ttgggtctat taatagtaat tttacttcat caggatttgc cttatataaa atactactta
    23101 ttaatgtatt tacacacaca ctctttcctg aacctgtaga accagctatt agtaagtgtg
    23161 gcatcttacc tatatctcca attataattt ttcctgctac gtcttttcca agtcccattg
    23221 caagaggaga gttaaaatta ttaaattctt cactttctag aacttctctc acaccaacca
    23281 tttgagcttc ttcatttgga acttctattc caattgcact tttaccagga attggggctt
    23341 caattcttat acttttagct gctaaactta aagctatatc atcagttaaa tttacaattt
    23401 tacttacctt gactcctgga cttggttgta tttcatatct tgttatagta ggtccaactg
    23461 taacttgatt aatttttgct tccactccaa aatctgatag tgtcttttct aaaagagaag
    23521 catttttcaa cactttcttt ttaccatttt catcagactt cttatttact ttatttaaaa
    23581 gctcaatgct aggcttttta tagtttgaat aatcctcatt aactggctct gctacaatac
    23641 tcataggttg agttttttct atatttaaat taggtttagc tatatcaact tttttttctg
    23701 gtttagtatc tacaactgga ttttcattgg tagctttttg taattctttt aaaacatcta
    23761 actctggcat actttgagtt ccttctaata tttctaaata ctcatcttct gccttattaa
    23821 atccaactat ttttatagtt ttatcatcta caccatcact attttcttct tcaaaatatt
    23881 catcttcttc atcatcatta ttaagacctt ttgacattaa ccctttaaag aaacctggtt
    23941 ttttatttat agtagtatca tctacttcat cagtcatcat atctattgca gattttttca
    24001 tatttgcaat tttatcttta aacgttaaat tgctgtcttt agatgcttta gattttgatt
    24061 ttgcatttga caccaaatct tttatagaaa tattaaatat aaacattaca gaaagtataa
    24121 gtgcgaagat acttattaac catccacctg ctataccaaa tattttactc atataatacg
    24181 caatagttgt tgctatcaaa ccactacctt gtccacttac acccaatttc ataacatcat
    24241 caaacatgtt accttttagt gggctatcta caggaagagt tcctgcattt aataatccat
    24301 aaaatacaaa tataaataaa ataattatgt agtatagttt agtctttctt agcctatata
    24361 tatattcatt tccatcaaaa aatcctaaaa gtcctgttat aattactata aatggtattg
    24421 ctattgaaag ccctccaaat agtcccttaa aaagattttg cattaacaca ggtatccatc
    24481 ccatagaatt agaatttaaa ctatataata aaaatacacc tataaatatt gttattaaat
    24541 tatgatattc tgcattaaaa cttaaggtat ttaccttctt ttttttcttc tttttcgtgg
    24601 ccattaatat cactccttat ttttagcaag ttttacccct tcacagcaaa aagtgctaat
    24661 gccttaacac taacactcct actttattac atcattatat cataaatttt attatttaaa
    24721 caaattttaa tcattatttt tttcttcctc agattctttt ataagctctc ttaatttttt
    24781 aagtgcttct tttagtcctc caacttcatc tataagacca taatccacag cttcttttcc
    24841 tattaataca ctaccaacat cacttacaag ttcatctttt tcatgcataa gtttttcaag
    24901 tacatctttt ttgatatttg atgttcttat tataaattga attattctat cttgcatctt
    24961 tttaaaatat tcaaaagtct catttatacc aatcacaaga ccagtagttc gcactggatg
    25021 tataatcatg gttgctgttg gtgctataaa tgagtaatct cctgctgtag caagaggaac
    25081 acctatacta tgacttcctc ctagaacaag agtaactact tttttagatg tactgtttaa
    25141 aagttctgca atagctaaac ctgcttcaat atctcctcca acagtgttta aaacaactaa
    25201 cactccttta acatcattac tttcctcaat tgagtatagc attggaatta tatgctcgta
    25261 ctttgtagct tttttttgag gatttcctat aaaatgtccc tcaatttctc caattatagt
    25321 tatacattga atatctttag gaggttgagg tggcatttca ttggtaccaa attgctttat
    25381 acattctctc tcttcgcaac tagattcttc actacaatta tctttatcaa atttttcatt
    25441 atcttctcta taatctttca taaaaaaact cctatcaaaa ttatatttaa tttagtttta
    25501 ccaaataaat caaatatatt aagatatata tgaaattctt aaatttgatt aaaaaataat
    25561 tgtattatac agtttatttt aaataaaatt gttggtgtat agcatgtact gctgtatgca
    25621 tatcttcttc actaactaaa caagatatag tcatatttga gtctgatgtt tgtaaaagag
    25681 atacccctgc ttttgataat cctctaacta cctttgacat gataccagac atttcatcag
    25741 caattcttga acatatcaat gttaccttag cacagtctct atttacttca taatctaatt
    25801 caaatttatc tagtatttcc tttaatgatt ttatatcagc atcttctaca acaaatgctt
    25861 tttctgatat aaagaaattt atcatatcta tagttataag tttcttttct atctcattta
    25921 atacttctgt aaacacttct tctgctgact taatcttaac ttgtgctacg ctatctttat
    25981 ttgcaacagc aaccttaaaa tctctttctt gttcatattc tatattgtct tctaagtgtc
    26041 tacataaaga acctattttt gtaccttcaa aagttggatt cattgtattc tttatggcta
    26101 aagttatatt tccactttta gccaactgta ctgctcttgg atgtattact tttgcacctt
    26161 tgtcagccat ttggaatact tcctcatagt ctataaaact caatacttta gcgtttggtt
    26221 ctactctagg gtctgcagtc attataccat ccacatcagt gtaaatttca actgtttcac
    26281 attctaaagc tttaccaata gcaactgctg atgtatcgct tccgcctctt ccaagagtag
    26341 ttatttctcc atcatctgtt acaccctgga acccagctat aactacaacc ttaccatcat
    26401 ctaaagctct ttttaccttt ttaggattta tatactttat ctttgcatta gaatattcat
    26461 cacttgtaat tatacctgct tgctgaccag taaagaaaac agaatctatc ccctgtgcat
    26521 tcaataaatt agcaagaatt gttcctgata ttatttctcc acaagacatt attaaatcaa
    26581 gttctctttt acttggctca tcatttactg cactacacaa atttataagt gtatctgtag
    26641 catatggagc tccttttctt cccattgctg aaactactaa tactaattgt aattcttcat
    26701 catttttttt gtatgctttt actatcttac atacttcatt cattttttca tatgattcta
    26761 ctgatgtccc accaaacttt tgcactaaaa tactcatttt ttcctcctaa atatatccct
    26821 catattctat aattatcatg tcattaccta ttttttttac atttctccat ggtacttcta
    26881 aaaatgactt atcttttctt ctggcaaaaa atcctttttc ttttggaatt agaagcgcta
    26941 atatatcgcc tgtagtttca tctagtataa ggtcacattc tccaatgacc cccaatcttt
    27001 ctcctgtgac caagttaact atttccttac ctgctatttc agataaattc atattttata
    27061 cctccagaga tttacttttt tcaatattaa tccaagtgta gaatcttttc tacatctctt
    27121 ccaactatac atgtaccaat attttcgata ttgaatacct tatcaacaac cttctttatt
    27181 gaattaatat taacattatt tatacattca agtatttcat ctgtagtttt tacttttttg
    27241 ctaagtaaca tagatttacc agtagacatc attctactgc tagtactttc taaatccaat
    27301 atataatttc cttttaactg ttccttgctt tcagatattt ctttttctgt aagatagttt
    27361 tctcttatat tttcaatttc tttctttatt aaattatata catcttgtaa attttctgta
    27421 ctcatgcttg caaatatacc taattcacca catttcctat ataatgtctg tgatgagtat
    27481 attgaatata ctaaaccttt ttcttccctt attttctgaa aaagccttga gcttatactt
    27541 ccaccgaaaa tattatttac cactgccatt gaatagactt cttcatcatt ttcaaaagga
    27601 atacctttta ggcacatagc taagttcacc tgttcagtat ctttattttt tgatataaag
    27661 caaggattaa acttagcctc acttatgtct atacttaaat ttttcttttc ccagtgtcca
    27721 aattttgatt tgattttctc caccatatca tcaaagttaa agtttccagc tatagaaata
    27781 acagcgttat ttggaatata atacttattt aagtattcta acatggattc tctagttata
    27841 ttgtacagag attcttttgt cccaattata ttcattccta atccatcatt agcatatata
    27901 ttttccacta ataaatcata agataagtca tctggagagt cttcatacat cttaagttct
    27961 tccaatatta taagtctttc cttatctata tcatttttat caaatttaga atttagtatc
    28021 atatcactca atacatcaat tcctgtatct atatgctcat ctattagttt tacataataa
    28081 catgtacatt ctttacttgt aaatgcattt atttgaccac ccaaattatc tattgaacta
    28141 gcaatctctt ttgatgttct gtttttggtt cctttaaaca tcatatgctc tataaaatga
    28201 gaaattccac tcacctgtgc ttcttctatc ctagagcctg catttatcca aatacctaat
    28261 gttattgact ttagatatgg tatttcttca ccaattattg taagcccatt ttccagtatt
    28321 tttgtcttat acattacatt ctcctaacaa tttattcttt gtttcatatt ggattattga
    28381 aaacactatg ttttaattat atttattttt tatatgtatt acattataag tcagtctttt
    28441 aattaattca actacaactt atacaatctt aaccaaatat ttatactttg tctacttaaa
    28501 tacatcacta agttttcctg gttttagtcc tttttctctt acaatagcta taatatcatc
    28561 tatacatttt gtcgttgcgt tggttggatg cattaaaatt atactactat ctttaatgtc
    28621 ttttttcttc attctatcaa tgattacctc tggttggtct ttgtatttcc aatctatagt
    28681 atcggcatcc catttgatag aagtataccc taatgcttta gcagccttta ctgtttctgg
    28741 accaaaagaa cctgctggtg cttgaaaaaa tttagttttt tcacctataa tttcttcaat
    28801 tatcttttta gaggtctcta tttgctcata attgtcttca tatgataatg tagaataatc
    28861 taaatgtttg tatccatgat tacctatttc atgtccttgt ttttttatct ttaataattc
    28921 atccttattc ttttctgccc attttccagt tacattaaat gtaatcttta cattttcttt
    28981 tttaagtgtt tctaaaatgg attctacgta ctctgtttcc catccaaggt ctatattaca
    29041 ggttaatgca acatatccac ttttatcctt tgtacctctt tcatatggta aatctacacc
    29101 attaaataaa ttaaatactg gcttgttgtt aaataacttt aataccatta cccctcctga
    29161 taatactaat aacactacta aaattagtat tatgattttt ttgagcttac tcttattaag
    29221 taccatcatt atcattaaaa ctccccctaa ttatgtacaa attgtttctt atttaatact
    29281 attaaaaata agctctgttt atgcactaaa tataacttaa gtgattctat atatatcaat
    29341 aaagctctct attaatcagc ttttaaatag cttctttata agagtaaagc ctgacagaaa
    29401 aagaactata agccatccat aactatcatt ttaaaattat ctactttttt gtatttaaaa
    29461 aagcaaaatc ctaagacttt gcttttaatt atataataag ttatttattt ttatgttctg
    29521 gttttggtaa aagaactttt cttgataaat taactcttcc tttttcatca atctctgtaa
    29581 ctttaacttc aacttcatcc cctatattca atacatcttc aactttggca actctttcat
    29641 gagctatatg agatatatga agtaatcctt cttttcctgg aagtatctca acaaatgctc
    29701 caaagttcat tattctactt accttacctt tataagtttt tcctacttct ggttcaacta
    29761 ctatattatt tataagttct tgagctttct taatcatatc aatctcaata cctgatataa
    29821 atacttcccc agtttgttca atatctatct taactccagt ttcgtctatt atcttagtta
    29881 ttatctttcc accaggtcct attacatctt ttatcttgtc aggatttatt tgcattttaa
    29941 caatcttagg tgcatatggt gaaagttctg gttttggctg agatatagtt tttctcatct
    30001 ctcctagtat atggattcta ccctctttag cttgttttaa agcacgttgt agaatttctt
    30061 tatctatacc atcaattttt atatccattt gtattgctgt tataccatac tctgttccag
    30121 ctactttaaa gtccatatcg cctaaatggt cttccatacc ttgtatatct gaaagcactg
    30181 caaccttacc atcatgcttt ataagtccca ttgctatacc tgcaaccata tcttttatag
    30241 gtacacctgc atcaagtaaa gataatgttg agccacatac acttgcttga gatgtagaac
    30301 catttgaact taatacttca gaaactaatc taatagcata aggaaattct tcttgagatg
    30361 gtattactgg taataaagct ctttctgcta aagcaccatg tcctatttct cttcttcctg
    30421 gtcctcttga tggtctagct tctccaacac tatatgcagg gaaattataa tgatgcatat
    30481 atctcttgtt ttcttcttca tctaacccat ctagtttttg aacatctcct aaagcaccta
    30541 aagtagcaac attaagtact tgagtttgtc ctctagtaaa tatggctgaa ccatgagctc
    30601 taggtatcat gccagtttca caccatatag gtcttatttc ttcaagtttt ctattatctg
    30661 gtcttacatt ttcatgtact ataagttttc ttacttcttc ttttattata tcttgtaata
    30721 cttcttctat atctccaaca aaatcttcaa aatcttctaa agtttcttca aagtgagcta
    30781 aagtttcttc tttaactcta tccatatttt ccattctctc taacttttca aaagtctgaa
    30841 ctgctttttt catcttatca gttgcaaatt cgcgaaccaa ttgagttatt tcttctcctg
    30901 catggtataa ttcaacaggc attttttctt ttccaacttc tgcaactata ccttctataa
    30961 actcaactat tttttttatt tcttggtgag caaataaaat agcatcaagc attacctcgt
    31021 ctggaacttc atcagctccg gcttcaacca tcattattgc ttcctttgta cctgaaacaa
    31081 ctagatgcat tgaacttttt tctctttgct ctgcgtttgg atttacaaca aatgcaccat
    31141 ctacaaggcc aacacatact gaacctgttg gtccattaaa tggtatgtct gatatagaaa
    31201 gggctattga agaacctatc attgctacta tatctggtgt acaatcttgg tctactgata
    31261 gaactgttgc aactacctga acatcatttc taaatccttt tgggaataaa ggtcttattg
    31321 gtctatctat caatcttgat gtaagtatag ctttctctga aggcttgcct tctctcttta
    31381 aaaaacctcc aggtatctta cctacagagt ataatttttc ttcataatcc acacttaaag
    31441 gaaaaaagtc tattccgtct ctaggtttgg ctgatttagt tgtatttacc attaccatac
    31501 tatcactgta tcgaactata caactaccac tagccatttc acaaatcttt cctatttcta
    31561 cagaaagttc tcttcctgca aaatccattt taaatatttt atgttcaaac attaatgctt
    31621 gtcctcctct tattaaaaaa cacgtatatc actctattta ctatattatc aaaaatacta
    31681 taaattaaca atataaaatt atcttcacat atatatgcaa aaaccttata ttactactaa
    31741 ttagaacaac ttatagccaa tatatctggc cctgtatgag agcaaataga aactcctcct
    31801 cgagtaaata atactcttct tgcttttatt cttttattta cttcatcttt taatatttca
    31861 caatcgtgta aattatctcc acaacctatt gtgacgattt ttccttctaa agacccttca
    31921 ttcatttcta aaattatatc gaccaattta cttgctatat tctttattcc tctaacctta
    31981 tttaccaact tagcttcccc attatcaaag aaaaatatag gctttatatt taacatattt
    32041 cctatcaaag cagttgcaac tggaactctt ccactctgct ttaaaaaatc aagtgtatat
    32101 ggtgcaaaaa gcaatcttac actactgcga gtattttcta attcatctat aatttcttca
    32161 aatcccagtc cttcttcaag aagttcacat gcctttataa catattgtcc actacctaga
    32221 gataaatttc tagtatcaaa tatatgtatt ttttcatttt catttacatc atttttagct
    32281 atcatagcac tttgaaaagt tcctgatgcg tttgcagccc ctgtcataca gattatatga
    32341 taaccttctg ttatgaactt atcaaacact tctttaaact ccatatatgt agcttgtgaa
    32401 gttttaggta tttgcttgat ttcttttact tttttataaa actcttcttt ctttatatct
    32461 actccttcta tatattccct atcattaaaa ataactgtaa gtggaactat ctctatataa
    32521 tctttttctg atatttcatc tggaatatcg cacaaactat cgcatactaa ctttattttc
    32581 aaaataatat cctccttatt ccaactaatt atcctgttat aaaatttcta tatttatcct
    32641 gtctttcctt ttaaattgat tatgtatttg tatactattt taatattctt acccaatatt
    32701 attcatttta taatttttta taacatataa actactttta ttattaacta ttttacttta
    32761 taatgaatta actataaaaa agcaggtata cactatacct gcttttttat aaagaatgaa
    32821 attactttct taatcctaat ttagctatta atgctctata tccttcaaga tctttttcct
    32881 ttaagtaagc taataagttt cttcttctac caaccatttt taatagtcct cttcttgaat
    32941 ggtggtcttt cttatgagtt tttaaatgtc catttaactc gtttattcta gctgttaata
    33001 aagctatttg tacttctgga gaaccagtat ccccttcagc tcttccatat tcttttatta
    33061 tttctgattt gtttatcatt tagattacct ccgtattttt ttagaaacgc ctattactaa
    33121 gcattgattg gagtattcaa atgctgagta atggttattt tccttaatca ttttatcata
    33181 cattacttgt ttttgcaaac atagttttca tacacataat ttgtatcatt atacaattga
    33241 ttttttaagt catctattga attaaacttt ctttcatctc ttattctttc caaaaattca
    33301 acaattatat tttccccata aatatctcta tcaaactcta aaatatttgt ttcaatagac
    33361 aaagtttttc cattaactgt tgggttatag cctacatttg tagcaccaaa ataagtctca
    33421 tctccaatat gtacaataga agcataaata cctctctttg gaacgagcat attattctta
    33481 aggtcaatat ttgccgttgg gaatcctata gttcttccaa ggtgtttaga atgtataaca
    33541 caaccttcta acttgtaatt tctacccaaa tattccttga cattagccat atcaccctgg
    33601 gatactaaac ttctaatata agtactactc actcttacat cattgatttt gatgggtttt
    33661 attacttcta cctcaaaacc aaattcatgt tctaagcttt ttaatagatt aacattgcct
    33721 tcttttgccc ttgcaaatgt aaagtcatgt ccaattacta tctttttagc ttttaatttt
    33781 tttactagta tctcatctac gaaatccttt gcaggtattt tagtcatata ctcatcaaat
    33841 ggtatgatta caactatatc tattcccaaa tcttctaata attttatttt atcatcattg
    33901 cttataatat tttttgttga gtttggtcta aagtaattta caggatgatt tgcaaatgta
    33961 aatacgatac tctgtatatt ttcttttttt gcatgttcaa ctgtttttcc tataagaact
    34021 tgatgtcctt tgtgtacacc atcaaaattt cctatggtaa tgacactttc ttttatgttt
    34081 gctatttctt ttatagattt tataatcacc ataataaatg ttccccgcta aaatataatt
    34141 tactcttaac ttattcacaa actattatag cataagtaaa agagatagac tatagaagtt
    34201 attatagtac tatctctttt gttgtttttt taaatacatt ggttatatga acatcttatc
    34261 acttttaaca cttattgtat tattgtgttt tgataatttt cctaatccta agaaattatc
    34321 tgtactgtat actcttacaa attcatcatc tttatcgaaa ttatttttta aaaacctttt
    34381 atcatctatt gagccaccat tactataata ttttatagca ttagggttta atacaacata
    34441 attaaacgaa tcaaggacat aatctatatc atataagtat ttgtctaaag ttttattttc
    34501 ataaaataat tctaattctt ctaatgttat tgaattatct aagtcaaatt taccagaaga
    34561 tgttctattc aaaaacgaca tatgagctcc acaacctaga tattctccta tatcatggca
    34621 aatgcttctc acataagtcc ctttagaaca ctcaacataa aacattactt tattaccttt
    34681 tatacttagt atttttatgt cttttatatt tactcttctt gtttttaaag taatttcaga
    34741 ttgtctacca cttcttacta aatcacacat tctctttcca tttaccttta aagctgaata
    34801 aattggagga agttgattta tctctcctct ttgtgtgtca aaagctcttt ctatgtcttc
    34861 attactaaat ttaaaatcat caactttttt taaaatttca cctgaagcat cataagtatc
    34921 tgtacttata cctaaagtaa gctcacatat atacgattta tctttgttta aaataacttc
    34981 acatactttt gtagctttcc ctatacagat tggtaaaaca cctgaagcat ctgggtcaag
    35041 agtacctgta tgaccaactt tttttatatt taaaatcttt ctcactctac ttacaacatc
    35101 atgagatgtc atacctgtgg gtttcaatat acttataatc ttattcattt tactgtcacc
    35161 ttaaattgat tttaacactg cctctagtac cattttcttt gcattatcaa tactatctct
    35221 aatagtacat ccagcagccc ttacatgacc accaccacca aataacttgg ctatttcact
    35281 tacatcaaca taattttttg acctaaaact cactttaatt tcattttgtt ttttctcttt
    35341 aaataaaatt ccaacttcta taccttttat gtctcttgta tatgttgtta ttccatcaac
    35401 atcattaaag ctaatattat ttctattcat catgtcttga gttaaaacta tactagatac
    35461 ctttgactga acctcccatg actaaagtca cagggttcct gcttcacaga attttgcata
    35521 ttaaaatatg tcttactaat tctccacagg ctatccccgt agttcctacg gttcttacat
    35581 aagttattta ttttgaatcg ttattagtct taatccttct tttaatatat ttatacttgc
    35641 atttatatct ctatcgtgag tttcattaca actaggacaa atccattctc ttatatttaa
    35701 atccttaact tcctcgtttt tatacccaca tttattgcat atttgtgaac ttgcaaagaa
    35761 tttacctacc tttacaattt ttctaccata ccaattagcc ttgtattcta attgacgaat
    35821 aaattctgac catgatacat ctgaaattaa gcgagatagt ttacgatttc taatcatatt
    35881 ctttacttgt aaatcttcta tgcaaataat atcattctct tttattaatt tagtagatag
    35941 tttttgtaga aaatcatttc tttgattagc tatatgttct tgaagtcctg caacttttaa
    36001 tcttgcttta tttctattta aactaccgat tgtttttctc gataattctc tttgtaattt
    36061 agcaagcttg tttaatgact tcttaagata cttaggattt tctataaagt ctccacaact
    36121 tgagatacaa aattctttaa ttcctaaatc taaacctata tgattattag tattttcaaa
    36181 tacttcaata tctacatcag tacagcataa tgatacataa tatctaccac ttggttcttt
    36241 agatatagta gcattaagta ttctaccttg aggtacttgt ttatccctta tcttaaccat
    36301 accaagttta ggtagtttta tatattgacc acaatacata atgtttccat ttgtaaagtt
    36361 agttttatat gaaaatctat taattttctt tgatttaaat ttaggaaatc ctgccttttc
    36421 tttaaagaat tttttatatg cattatctaa atcttttaag gcgttttgta gtgaaaattt
    36481 gtcaggttcc ttaagccatt ttaattcttt ttttaaattg gtcaaatcag aactacactg
    36541 tttataagta aaagtttctt tatcgctttt ataaacatct attcttttag caagatattt
    36601 attatataca aatctacaac atccaaaagt tttgttaatt
//
LOCUS       DAEPXW010000036        36419 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.037, whole genome shotgun sequence.
ACCESSION   DAEPXW010000036 DAEPXW010000000
VERSION     DAEPXW010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36419
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.037"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            71..1783
                     /gene="ptsP"
                     /locus_tag="KRM55_001735"
     CDS             71..1783
                     /gene="ptsP"
                     /locus_tag="KRM55_001735"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBH1593983.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            2106..3656
                     /locus_tag="KRM55_001736"
     CDS             2106..3656
                     /locus_tag="KRM55_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1593984.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGDEFVMLLSGFTSREEV
                     EDLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
     gene            3682..6384
                     /locus_tag="KRM55_001737"
     CDS             3682..6384
                     /locus_tag="KRM55_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1593985.1"
                     /translation="MKNVSKKFFVCTIIVLLTFLCFSKFAIYVFDKQEKKETKVVENM
                     LNAYKNNIILNLTEKFNYSKDLTSVLVSNNYSIDKLKPIADEILKNNSCIYISVVEKY
                     NVAAFFSNSVKKDIINTPIQELNYSYSLANSIKGLVVEGPSKDQFSNGDVFLITNPIY
                     KNGEYWGEITVALDAKKVVESFNLNKLKESGFEYELWRVHLDNGSKSTIEISTKDFNF
                     SKSHEIKFKLPTVWTLSIVYKNGWNNKNIDFIVFVILLIISILIGVMTFIYIEKKSIS
                     KELNQQSLKNLETGILNREGFLIKLQEHLNRKNNEIVLLYICITNYSKFAPVMSFEKR
                     QDYLTHIVKNLDNYIKSSHFIARISEEGFVLALEENCDKNELLNIEKGISLELLRKIK
                     VENKQVFLTIGYGSSRCVGDRKDAESLLLSAIEDYERRFPAMSPIHDFTKKCEDMLDE
                     KKQIVFGEYPDLEINKLSKVIYKYYKKVQRIMYKDYNIDIGNRRGYMRDVEVLIDYNS
                     ERMLYLFLIDICKFGKFNELFSIEIGDVILKEVSNKLKTIFSNYLYRINGDVFLGISI
                     DKESYLDTLHKVNEVFNSSLSVEDVLFDVKCNIGICQYPYHGENPYDLLEKVQIALEY
                     AKKDVKSNVKVYDKELTEEIYHENNIIKDLKKGLEEQTLEVWYQPIFNVSKNCYIKAE
                     ALIRLRNKEGGYYSAYEVITYAEKHGLIKDVGLYVLKKACDVTTKIKDKNIDFEQMQL
                     NLSVQQIVHKQCANDILSCIENCGLDKKYICVEVTETVLMETFEIVNVTLDKLKKEGI
                     SIALDEFGSGFSSINYLANLPIENLKIDKELVEQITYSKKQFELLKTIVQIAKINGMD
                     IVAEGVETKETLDLVVTSGVNLIQGHYFSEPLSEDKFIELMIEE"
     gene            complement(6890..7555)
                     /locus_tag="KRM55_001738"
     CDS             complement(6890..7555)
                     /locus_tag="KRM55_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1593986.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVTLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            7899..9329
                     /locus_tag="KRM55_001739"
     CDS             7899..9329
                     /locus_tag="KRM55_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH1593987.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            9697..10275
                     /locus_tag="KRM55_001740"
     CDS             9697..10275
                     /locus_tag="KRM55_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH1593988.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFMMLVLGKLKAKV"
     gene            10305..10451
                     /locus_tag="KRM55_001741"
     CDS             10305..10451
                     /locus_tag="KRM55_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH1593989.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            10756..12135
                     /gene="scfB"
                     /locus_tag="KRM55_001742"
     CDS             10756..12135
                     /gene="scfB"
                     /locus_tag="KRM55_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBH1593990.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYAERQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNSDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            12164..12661
                     /locus_tag="KRM55_001743"
     CDS             12164..12661
                     /locus_tag="KRM55_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBH1593991.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            12959..14623
                     /locus_tag="KRM55_001744"
     CDS             12959..14623
                     /locus_tag="KRM55_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBH1593992.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            14636..17086
                     /gene="recJ"
                     /locus_tag="KRM55_001745"
     CDS             14636..17086
                     /gene="recJ"
                     /locus_tag="KRM55_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBH1593993.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEEAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDDSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            17099..17611
                     /locus_tag="KRM55_001746"
     CDS             17099..17611
                     /locus_tag="KRM55_001746"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBH1593994.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            17685..19892
                     /locus_tag="KRM55_001747"
     CDS             17685..19892
                     /locus_tag="KRM55_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBH1593995.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            19917..20366
                     /locus_tag="KRM55_001748"
     CDS             19917..20366
                     /locus_tag="KRM55_001748"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBH1593996.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            20381..20995
                     /locus_tag="KRM55_001749"
     CDS             20381..20995
                     /locus_tag="KRM55_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1593997.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            21086..22642
                     /locus_tag="KRM55_001750"
     CDS             21086..22642
                     /locus_tag="KRM55_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBH1593998.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNADNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFVVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            22632..23894
                     /locus_tag="KRM55_001751"
     CDS             22632..23894
                     /locus_tag="KRM55_001751"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBH1593999.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            23968..25755
                     /gene="aspS"
                     /locus_tag="KRM55_001752"
     CDS             23968..25755
                     /gene="aspS"
                     /locus_tag="KRM55_001752"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBH1594000.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMLTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            26214..27446
                     /locus_tag="KRM55_001753"
     CDS             26214..27446
                     /locus_tag="KRM55_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH1594001.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            27460..28266
                     /locus_tag="KRM55_001754"
     CDS             27460..28266
                     /locus_tag="KRM55_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBH1594002.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(28378..29247)
                     /locus_tag="KRM55_001755"
     CDS             complement(28378..29247)
                     /locus_tag="KRM55_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1594003.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            29619..31046
                     /locus_tag="KRM55_001756"
     CDS             29619..31046
                     /locus_tag="KRM55_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBH1594004.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIGSVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(31123..31392)
                     /locus_tag="KRM55_001757"
     CDS             complement(31123..31392)
                     /locus_tag="KRM55_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594005.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMRGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(31395..32837)
                     /gene="nhaC"
                     /locus_tag="KRM55_001758"
     CDS             complement(31395..32837)
                     /gene="nhaC"
                     /locus_tag="KRM55_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH1594006.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(32862..34028)
                     /locus_tag="KRM55_001759"
     CDS             complement(32862..34028)
                     /locus_tag="KRM55_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1594007.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKYYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(34253..36373)
                     /locus_tag="KRM55_001760"
     CDS             complement(34253..36373)
                     /locus_tag="KRM55_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1594008.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSNNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
BASE COUNT        14153 a         3985 c         6237 g        12044 t
ORIGIN      
        1 aaaaatgtaa attatttata taaatttata aagtttatgt gctagatgat attttttagg
       61 aggtagggtt atggcttaca aaggaatagg tgcttctcct ggtgttgctt tagggaaagc
      121 gttagtagtt gaacatagtg aattagtaat tgaaaaaaaa tctatagata atgttgaagc
      181 tgaaattgct aaattagaag atgcagttgc agtttctaaa gaagaattag taaaagttaa
      241 ggaaaaggct tctgaagaat taggagcaga ggaagcagaa atatttgaag cacatttatt
      301 agttttagaa gacccagagt taattggttc tgcaatagat aaaattaaaa ctgaaagtgt
      361 aaatgcagag tatgctttaa atgaaataaa agagatgttt gttagcatgt ttgagtctat
      421 ggacaatgag tacatgaaag aaagagcggc agatataaaa gatgttacaa atagaatact
      481 tagacatata ttaggaatta aagttgttga tttatctgct ttaagcgaag aagttgtatt
      541 aatagcacat gatttaactc catcagacac agcaactatg aataaaaaaa tggttttagg
      601 atttttaact gatataggtg gaagaacttc tcatactgct atcatgtcta gaactttaga
      661 aatagctgca atcgttggat taaatgatat aacttcaaaa gttaaggatg gagattttgt
      721 ggttttcaat ggagacacag gtgaagtaat cgtgaatcct gatgaagaga ctataaataa
      781 atatactgaa ttaaaagcta agtatgaaga tgagagaaaa gcattacagc tattaaaagg
      841 aaaaccatct gtaactttag atggaaaaca tgtggaatta gctggtaaca taggaacacc
      901 taacgatata gaaggtctaa taaagaatga tgctgaaggt gttggtcttt atagaacaga
      961 atttttatac atggatagag attctttccc aacagaagaa atacaatatg aagcatacaa
     1021 agctgtatta gaaggaatgg atggaaagcc tatagttata agaacattgg atataggtgg
     1081 agataaagaa ttaagttatt taagtatgga acctgagatg aatccattct taggttacag
     1141 agcaataaga ctttgcctag atagaaaaga tatatttaag actcaattga gagctttata
     1201 tagagctagt gttcatggaa gattaagaat catgttccca atgatttcat ctttagaaga
     1261 gttgttacaa gctaaagaag ttgtaaaaga agttttagca gaacttgatt ctgaaggtgt
     1321 ggcttatgct aaagatgtag aaattggtat gatgatagaa gttccatctg ctgctgtgat
     1381 atctgatgta ttggctaaac acgtagattt cttctctata ggaactaatg atttaattca
     1441 atacacttgt gcagttgata gaatgaatca aaagataagt tatctttaca atcaatttaa
     1501 tccagctgtt ttaagactta taaagactgt tatagacaat gcacataaag aaggaaaatg
     1561 ggcaggtatg tgtggagaat ctgctggaga ccaaaaaatg ataccaatac ttttaggtat
     1621 gggattagac gagttctcta tgtctccaat atcaatactt cctgctagaa agttaataac
     1681 ttcagttaaa gagtcagata tgaaaaaatt agctgatgat gtacttaata tgggtactgc
     1741 tgaagaaata aaaagctata tagaaaagac ttttaatata taattaatgt tatatagtta
     1801 ctaaaattca tttttctaaa taacaaaatt atattttacg aataaaaaaa ctatagtata
     1861 tcatatatac tatagttttt ttgttatata aattacgtat caaaatttat aaaatgaata
     1921 gatataatta ctaaatatgt gatagtattg gctataatag gatataaaaa ataatattgt
     1981 aaaaaaaagt ttatatttag taatgaaaat ttaacgtttt acttgaaatt atgtgttttg
     2041 taatgtatta ttaaggttct aataggaaca ttttcatcaa tttttctata gtgggggtag
     2101 gaattatgag gtacaaaaaa agaaatatag ataagtcaag tgaactttca tttcaatctc
     2161 tagcaaaata ttttataact ttctatatag taattatatt aattattctt tctatgtttt
     2221 gtataaatac aatatgggtt atgaaaaaag ataatcaaga tttattatct acaacatcaa
     2281 atcgtattga agatagggta ggagaaacaa ttaagctatt gaactctttg agtaaagata
     2341 attacataat agataatagt gtgaatggca tagataaaag taaagaactt tcaatgtata
     2401 gtgatgaatt tgggtatatg atgatatgtt ttgttgataa gaatataatt gtgtgggatg
     2461 aagaaggtgg taatattagt ctagctggtc gtgattatat gcagaaactt tttgcaacaa
     2521 aaaaatatca agttacagat agttttgcag caggggctga tggaaaaact ttaaactaca
     2581 ctattgcatc acctataata aagaatggaa atgtagatgg ttgtgtattt gcagcaattt
     2641 actttgatga gataaaggat atactcaaac aaggaaaagg tcaacagcaa cagaatttca
     2701 tattatttgg aagtgaaaat caaataatga atttaacaag tgatgaaact gcatatggag
     2761 agaagtatat gaagttatcg cagaaaacaa aatatcttgg aaccaatgca aaaaaagtag
     2821 aaaaggatat gtttaataat aaatcaggtg attattgggc ttttgaaaat ggaaaattat
     2881 actttatgtc ctataaacca attaagaaca caaattggag tttattttgt aaagttaatt
     2941 tcttagatat ttttgcatta aatttaattc ctatgggagc tattctatct gttataactt
     3001 tagtatttat tattttgatt tgtatggaga aaagcttcat gaaaaaacga atggaagtta
     3061 ttgatatgct tttaggttct gttcaagaat tagaaaaacg tatatatcaa acagaaagac
     3121 ctagtgaagt agactttaaa gaaattattc agctcacaag taaaggtctg actgatggat
     3181 taactggtgt tgtaacacgt actgtatttt ttgaccaaat ttataatcgt gttgaaatgg
     3241 aggaaaatga taaattatct gtaatttcat ttgttgattt agatgatttg aaatgtatta
     3301 acgacttata tggacatgaa attggggata tggttttgaa aaatgttgga tatgtacttc
     3361 gtgaatatga gataaaatat aatggtttaa ttgggcgcta tggtggagat gaatttgtta
     3421 tgttgttatc tggttttaca tcgagagaag aggtggagga tttattggat gagattgcta
     3481 ttcgcttaca tactgaagta ctaacagatg atggtatcat tcaaactcat tgtagtgttg
     3541 gagctgtagt atgtagtgta aaagacaata aagatataga taatttatta aaacaggctg
     3601 atgaagcttt atactatgtt aaacgtaatg gaaaaggtaa ttatcattta gtttaatgta
     3661 tgtggaagga gtttatatca tatgaaaaat gtatctaaaa aattttttgt atgtactatt
     3721 attgtattac taacattttt atgttttagt aaatttgcta tttatgtttt tgacaaacaa
     3781 gaaaagaaag aaacaaaagt agtagaaaac atgttaaatg cctacaagaa taacattatt
     3841 ttaaatctga ctgaaaaatt taattatagc aaagacttga catcagtttt agtttcaaac
     3901 aattattcta tagataaatt aaaacctatt gcagatgaaa ttcttaaaaa caattcttgc
     3961 atatatattt cagttgtaga aaaatataat gtagctgcat ttttttctaa ttctgtcaaa
     4021 aaagatatta tcaatactcc aatacaggaa ctgaattatt cttattcatt agcaaattct
     4081 atcaaaggat tagtcgtaga aggtccttct aaagaccagt tttcaaatgg agatgtgttt
     4141 ttaattacta atcctattta taaaaatgga gagtactggg gagaaattac agtagcttta
     4201 gatgccaaaa aagttgtaga atcttttaac ttaaataaat taaaagaatc tggatttgag
     4261 tatgaacttt ggcgtgtaca cctagataat ggttcaaaat ctacaataga aatttctact
     4321 aaagatttta atttttccaa atcacatgaa attaagttta aacttccgac tgtttggact
     4381 cttagcattg tgtacaaaaa tggatggaat aataagaata tagattttat tgtatttgtt
     4441 atattgttaa ttatttccat attaataggt gtgatgacat ttatttacat tgaaaagaag
     4501 tcgattagta aggaattaaa tcaacagagt cttaaaaatt tagaaactgg tattttgaat
     4561 agagaaggtt ttttaattaa gttacaagag catctgaata gaaaaaataa tgaaatagtg
     4621 ttgctgtata tatgtattac taattatagt aaatttgctc cagttatgag ctttgaaaaa
     4681 agacaagatt atcttacaca tatagtaaaa aatctagata attacataaa aagttctcat
     4741 tttattgctc gtataagtga ggaaggtttt gttctagctt tagaagaaaa ttgtgataaa
     4801 aatgaattgc ttaacattga aaaagggatt tccttagagc ttttacgaaa aattaaagta
     4861 gaaaataaac aagtattttt aacgattggt tatggctcat ctaggtgtgt tggtgataga
     4921 aaagatgcag aatctctgtt actttcagct attgaagatt atgagagaag atttccagca
     4981 atgtctccta ttcatgattt tactaaaaag tgtgaagata tgcttgatga aaagaaacag
     5041 attgtatttg gtgaatatcc agatttagaa ataaacaagt tgtctaaagt aatatacaaa
     5101 tattataaaa aagtacagcg tattatgtat aaagattata atattgatat tggaaataga
     5161 cgagggtata tgcgtgatgt cgaagtatta attgattata attctgagag aatgttatac
     5221 ttatttttaa tagacatatg caagtttgga aaatttaatg aactgttttc tattgaaata
     5281 ggagatgtta ttttaaaaga agttagtaac aaattaaaaa caattttttc taattatcta
     5341 tatcgtatta atggagatgt atttttaggc atttcaatag ataaagaatc ttacttagat
     5401 actttacata aggttaatga agtatttaat agttctttaa gtgtagaaga tgtacttttt
     5461 gatgtaaaat gtaatattgg tatttgtcaa tatccatatc atggtgaaaa tccatatgac
     5521 cttctggaaa aggtacaaat tgcattggag tatgcaaaaa aggatgtcaa aagtaatgtt
     5581 aaagtttatg ataaggaatt gacagaagag atttaccatg aaaataatat tattaaggat
     5641 ttaaaaaaag gtctggaaga acaaacacta gaagtttggt atcagccaat ttttaatgtt
     5701 agtaaaaact gttatataaa agctgaggca ctaattagat tgagaaataa agagggcggt
     5761 tattattctg cctatgaagt tattacttat gcagaaaagc atggacttat taaggatgta
     5821 ggtctatatg tactaaaaaa ggcttgtgat gtaactacaa aaataaaaga taaaaatata
     5881 gattttgaac aaatgcaatt aaatttatct gttcagcaga ttgtacataa gcagtgtgca
     5941 aatgacatat tatcatgtat tgagaattgt ggtctagata aaaagtatat ttgtgttgaa
     6001 gttacagaaa cagtacttat ggaaactttt gaaattgtaa atgttactct tgataaacta
     6061 aaaaaagaag gcattagcat agctttagat gagtttggtt ctggatttag tagtataaat
     6121 tatctggcaa atttacctat tgaaaattta aaaatagata aggaattagt agaacaaatt
     6181 acctattcta aaaaacaatt tgaattatta aaaactatag ttcaaattgc taagattaat
     6241 ggcatggata ttgtagcaga aggtgttgaa acaaaagaaa ctctggattt agttgtaact
     6301 tcaggtgtga atttgattca aggtcattat ttttcagaac ctttaagtga agataaattt
     6361 attgaactta tgattgaaga ataaaggtta ataaaataaa gatttaaggt attgaaaaat
     6421 aattaaaagt atttaataat agaattaggg aagaataagt ttataattaa aaataattga
     6481 ttagtagtta ataaaataaa tgtgatatcc aaataaatcc taaatctaat ttgagtttta
     6541 atatagatag tctaaagttt gattattaaa gatttaattg taagttgtta cagttgatga
     6601 tattgattag agattaaagt ttagagtaga aagttacctt aaatttaaaa atgcaagata
     6661 acccaatcta aaaattataa tcactcgata ggtttaagga tttatttgtt tattataaat
     6721 aggagggtgt ctcaaaatga actttttagt ttatgaggca ctctctttta tatagaatta
     6781 aatatatttt attatttcaa caatgaaaaa gaagcttatc tctattttga gacagcctct
     6841 ttgtatacta ttattaattt aatcaataac ataatttaaa attatattat tagttaagat
     6901 ttcctgcttt attagtaaat aattctttaa tagcattgtt tctggaaact aaatcgttat
     6961 cagagttgtt tgtttttttc ataatcactg aataacgttt tttatttata aaaaatatta
     7021 aaatcttatc atcatcaaaa ttgtattctt tatatctgtc aatagactca taacctagat
     7081 ttagaatgtt tttgtctttt atactatcta catctaaaat atatgatggg tcagccttta
     7141 gtaatatatt aattaaacat ttttcttcac cagcacagaa taactccatc ttacttgata
     7201 tagatttaga ttgctctgaa gttatttttg caggaataag gttgtcatta tcatctctta
     7261 gaagataacc atgtgtgtct tgttgatata ctaaagtaac ctttttctta ggaacactaa
     7321 tcattttatc taaatgtaca taatgatgat tttcaacaaa accttcattt aatatttcaa
     7381 caaagttatt aattttacct aggcaaaaag attctataga ttctttacag aatttatttg
     7441 taaatggtat tatgtttacg ttttcctcgt ctgtattcca tgctatagca taatccaacg
     7501 aatatacttc ttcctctata tctgcaaaat tatattgtac tatgtttcct ttcaaaatta
     7561 ctcgacctcc atcttataat atatttaata tactttataa aacttatatt atatttaaat
     7621 aatatcataa attggataaa tatgatatag taaataagaa aaaatttgaa aaaaatcact
     7681 ataaatgagt aataaatata aatagtgtat actaatggga tggaaaatgt ccactattaa
     7741 ctttattacc ccacatatat aagataaaat tattaatata aaatataatc tatcgacaat
     7801 gaatagactt ttaaataaac ttaatataaa attaattaaa taagtgctta aaaacgattt
     7861 actttaatga tagaatcata ttaaaggagg ataattttat ggatataaag aataaaatta
     7921 aatctatatt tttaccagaa aaaaatgact atttagatga tgaagaattt gagtatgata
     7981 tagaaaataa tgaagaagat ttaaaggaag ataacaaagt acatttaaat gatttaagca
     8041 gagtaaaata tgattacaga gagttaaaag acatagaaaa ccaaacagaa gagatgtgtc
     8101 tgctagcagt aaagcaggat ggtactataa ttgagtttgt aaaggacaag acttataaag
     8161 tatgtatgga agcagtaaaa cagacatata aatctcttaa gtatataaca aatcaaaatg
     8221 aggatatttg tatagaagca gtaaaacaga actacagagc tttgtactac ataaataata
     8281 agacagaaaa tgtactaatt gaggctataa aaaatgcatc aacttatgat gtcatggaag
     8341 tatttaaatt tgtggaagag caaacagaag atgtatgtct agcatttata gaaagggcat
     8401 ctaaaaatga tgttgcagag atattaaaag gaataaaaga gcaaactcca gccatatgtt
     8461 tagaagctgt aaaaaaagat ggaaaatctt tagcttatgt aaaggaacaa agtaatagta
     8521 tatgtttaga agctgtaaaa gaaaactaca gtgcactatc ttgtgtaaaa gagcaaactg
     8581 aagaaatatg tatagaagca gtaaaacaga atgactttgc attgtattat gtaaatgaac
     8641 agacagaaaa aatatgtatg gaagcagtaa aaagaagtta tatggctcta cagtatgtaa
     8701 ataagcaaac agaagagatt tgtttggaag cagtaagaat tgatggaaga gcattacagt
     8761 acgtaaaaga gcaaacagaa gaaatttgct tggagtcagt tagacaaaat ggaaaagtac
     8821 tgcaatatgt aaaaaaacag actgaaaata tatgtataga agcagtaaga ggttcatttg
     8881 aagaacttga aataaaagaa atattaagtt atgtaaagat accaacagaa agaatatttg
     8941 tagaagcagt aaagcaaaat ggaaaaattc ttaaatatgt agaaaatcag acagaattaa
     9001 tatgtttaga ggcagtaaga gaaaactata atgctttagc ttatgtaaag gaacaaacag
     9061 aaaagatttg tttagaagca gttaatcaaa gttatgaagc gcttaaatat gtgaaagaac
     9121 aaacagaaga agtttgtcta aaagcagtaa aacaagatta tagaatgttg aaatatgtaa
     9181 ataatcaaac agaaaaaata tgtttagaag cagtaaagca aaattataga gctttagaat
     9241 ttgttgataa tcaaacagaa aaagtttgtc ttgaagcagt aaaacagaat agaaaagcac
     9301 tacagtatgt aaaacaaaaa caaagttaaa aggctaaaat atatggggaa tatatgcaaa
     9361 taaataaaat ttgatatttt gtaataaata aaatgggtat ctcaaaagga actttttagt
     9421 ttgtgaggta ctctttttat atgaaatgaa atatattttt agccttttaa caatggggaa
     9481 aaggtttatt tctattttga cataggcttt ttatgcatat aaagcttgat aaaattgttt
     9541 tattataatt gttttgttat ataaataata agaagaaaat tatataggtc tttttttgac
     9601 cagttttaca tttttaacaa ctagttttgt aaagtatatt gaattttctc aaaaaagaat
     9661 gtactctata tatgtaaaat ttttttggag gtaaaaatgt ttaaaagata tgctgaaaaa
     9721 atgacatctg ttttaatttg taataatatg atagataata atgaatctaa agtctattct
     9781 tatggatttg aaatattaat agctttcata gttaatataa ccaccatgct gtttataggt
     9841 tttttatttg gtaaatttac atatgtatta ttttttttaa tgtgttattg tccaataaga
     9901 caattttcag gagggtatca tgcagacaat tattttagat gcttattaac ctttattttt
     9961 ataattttat ctacaatctt aattatagaa aatataaata tagacttatt taaaaatatt
    10021 attatgatta ttgcaagtgt tagttgggtt ggaatttgtg ttctgtgccc aatagaacat
    10081 aggagtaacc ctataagtga tagggaaaaa ttggtttata agaaaactgc tatatttata
    10141 tctacagtag tgttattgat aacaatttta agtctttctt tgagtatatt tgtagattat
    10201 ttcacatata gcgcatttgc catgttttgg atttttatga tgttagtatt aggtaagtta
    10261 aaagctaaag tataagtaaa atatgtatga gggagagtta agttatgaaa aagtttattg
    10321 taagatttat gaagtttgct agctcattgg cacttagcac tgctattttg tcagctaata
    10381 gtacctgtcc ttggattatt catcagccta aagtacccaa agaaatcagc aatctaaaga
    10441 agacaaatta aatacaagca cttatttata caaaattatc aggaaaaaag aaattattat
    10501 attttaataa gattaaaaca atataaaatc agatacaaaa tttattttat ttattttata
    10561 ggagcctaat acctatttgg taatatatta gtgcgccaat ttagggggat atagtgtatt
    10621 taatgaaatg acttacggag agtaagtcat ttttgtattg tatgtatttt atgtaaactt
    10681 atgatataat gaagggtaaa gtttaattaa aataataaaa aactttagta tagatagtaa
    10741 tttaggaggt agggtatgag tatgatacat aaattttcta tgaatggata taatatcgtt
    10801 ttagatgtga atggtggagc tgttcatgtg ttagatgatg ttgcatacga tttgttagat
    10861 ttttataaag aaaaaagtaa agaagaaata ttagagatat taaaatcaaa atatcaagaa
    10921 gaaaaaataa atgaagcata tgaagaaata ttaaatttgg aaaaagaggg tcttttatat
    10981 acagaagata catatcaata tcatccaagc tttgtacata gagagcctgt agtaaaagct
    11041 ttatgtttaa atgtagctca tgattgtaac ttaaaatgta aatactgttt tgcagctcaa
    11101 ggtgattttg gaggagaaaa agaacttatg agttttgaag ttggtaaggc agcaattgac
    11161 tatttgattg ctaattcagg aagtagaaag aacctagaga tagatttctt tggtggagag
    11221 cctttgatga actttgaggt tgtaaaacaa ctggttgact atggaagaag tgtagaaaaa
    11281 gattataata aaaatataag atttacaata actacaaatg gtgtactgct aaatgatgag
    11341 attatagatt atataaatga aaatatgcat aatgtagttt taagtttaga tggaagaaaa
    11401 gaagttaatg ataatatgag accaacttta aatgataaag gaagttatga tattacatta
    11461 ccacgattta agaaacttgt ggaaaaaaga gcaaaagata agtattatta tataagaggt
    11521 acttttacaa gagataattt agatttttca aaagatgtta tgcattttgc agatttagga
    11581 tttaaattaa cctctgtaga gccagtcgtt ggagatgaga gtaatccata tgcacttaga
    11641 gaagaagatt tacctaaaat atttgaagag tacgaaaaat ttgctgtaga gtatgcagag
    11701 agacaattac aaggagatgg atttaaattt ttccatttta tgatagacct aaatcaaggt
    11761 ccatgtgtaa taaagagaat aactggatgt ggagctggaa atgagtatct ttctgtaact
    11821 ccaaatggag atatctatcc atgtcatcaa tttgttggaa atgaagaatt taaaatggca
    11881 aatatatttg atgaagaaat agtacttcca gaaaatttaa aaaatatgtt tagagaagct
    11941 catgtatata ctaaagaaga gtgtaaacaa tgttggaata agttttactg ttcaggtgga
    12001 tgtcatgcaa atgcgataaa ctttaatagt gacatatcaa aaccatatga attaggttgt
    12061 gaaatgcaaa gaaaacgtac agagtgctct ataatgatac aagctaagtt aatgttagaa
    12121 ggagcaacca actaaattta tattttaaag gagttgttta tatatgatta gagattattt
    12181 agaagataaa cctttaattg acgaaagtgt atttgtggca aaatcagcag atgtaattgg
    12241 aaatgttaaa ataggcaaag attcaagtat atggtacaat gcagtagtta ggggtgatga
    12301 aggaccaata actattggag aaaacactaa tatacaagat tgttctatag tgcatggaga
    12361 tacagaaact ataattggta acaatgtaac agttgggcat aggtctatag ttcatggttg
    12421 taaaattagt gataatgtgt taattggtat gggttcaata atattggata atgctgaaat
    12481 aggagaatat actctgatag gagcaggtac actaattaca tctaataaga agtttccacc
    12541 aggtgttttg ataatgggtt ctcctggtaa ggttgttaga gagcttacag aagaagataa
    12601 aaaatatatt gatgaatctt atgaatggta tttagaggca gcacaaaatc aaaaatatta
    12661 gtttaaagag tggttgtttc aaaacatatt taaatctgtt ttgaggcaac cactaattta
    12721 ttttattaga ttttgttgat attttagttt tcaaaaagta tttgattaaa ccagatataa
    12781 aatgtcaaaa ataaaaatta actgagttaa ataattttaa taaaattggt agtatatgtg
    12841 ataaaattaa atattaaaga ggatatagga tattagaata tcaattggtg aaataatgtc
    12901 atatacgata aattaaggtg taagtttttg ggtataccta tcttaggagt gagaagattt
    12961 gagaataagt tatagaaatt taaagcgata tagagaaatt ggatatgttt taataaagta
    13021 tggttttagt tttattgtag aaagactaaa tatagaagga attgcctata aaataccact
    13081 atttgaccca ccagaagaaa taaaaaatat gacaactggt gagagaatga aaagagtttt
    13141 agaagaacta ggacctacat atataaaaat aggacagata ttgagcacaa gaaaagactt
    13201 gttagaccag gatataattg atgaaatatc aaaactcaga gatgatgtag agaaatttga
    13261 ttcaaatata gctattgata tatttaaaga agaagtgggt ttaagtatag aagaaatatt
    13321 cttagaattt aaagaagaac caatagcagc agcttcaatt ggtcaagttt atgaaggtgt
    13381 acttaaaacg ggagaagaag taatcgtaaa aattcaaaga ccaaatatag agaaaataat
    13441 aaaatctgat ttagagattc ttagaactat tgcaaatact ttaaaagatt taaaaaagga
    13501 ttttaattta gatttagtac agatgattga agaatttcaa actcaattaa tgagggaact
    13561 tgattataca tttgaagcta taaatgcaac taaattctct aggatattta aaaatagtga
    13621 tgaagtatat atacctaaag tatattcaga atataatact aagaaaattt tagtaatgga
    13681 gaaagttaat ggtacaaagt taagtgatgt agaaaaaata aggagactag gttataacac
    13741 aaaaactatt gttgaaatag gcgttaggtc attttttaca caggtattat ctcatggatt
    13801 ttttcatgca gacccacatc caggtaatat attcgtagtt gctaaaaata agatagcata
    13861 tatagatttt ggaatgattg gaattattga taataaaact ttaaaccaat taaatgaaat
    13921 tgcattagca ggtgtagaaa agaatgttga caagataata tatctattga tagaaatgga
    13981 tgcattaaat ggagaggctg atattaaggg acttagacag gatttacttt atctaataca
    14041 ttattactat gatatttcta tagaaaaaat aaatgtaaca gatatattaa atgaactatt
    14101 taggtttttt agacagtata aaatagtcat gcctgcacaa tttgtaactc ttgcaaagac
    14161 agttataaca ttagaaggaa caagtagaac tttaaacaca gatttttctt ttggttctat
    14221 gggaaaagag tttatgaaac atcattataa gagtaaattt aaccctaaaa atgttgtttt
    14281 aagttcaaga caaaatgtag aagaaatatt actggacata aaaactattc caaagcaatt
    14341 aaaagcaatt ttaaaaaata tagaaagaaa taatataaaa atgcaaattg aagatgttaa
    14401 aatgacgagg ttagaaaatt gtataataga gctaacatct caaatatctt tgagtttagt
    14461 gttggcatct attatagtag gttcttctct tataattgca tctccaaata tagaaaataa
    14521 tatatggata aaatttactg caatagcggg tttctttata tcctttataa taggcctttg
    14581 cttagttata agaagtatta ggtcaaaata caaaaaagat tagggggaat taaatttgaa
    14641 aaaatggata ttaaagtata aaggtaagat agaggaaagt gaatttagca aaaaacttaa
    14701 tatttccccg gaaatctgcc aaattttaaa aaatagaggg atatgtactg aaaaagattc
    14761 agagatattt atgaatccat ctttagatta tttaagagac ccttttttaa tgaaagatat
    14821 gcaaaaagct gttgatagaa taaagttagc agttgagaag aacgaaaaaa tttggattta
    14881 cggagattat gatgttgatg gtgtatcatc tacatctatc ttgtgcttat attttaagag
    14941 tataggttac aatgttgatt actatattcc taatagatta gaagaagggt atggtataaa
    15001 tgaagaggct attaagctta taagctctag gggatgtgac ttgattataa gtgttgactg
    15061 tggaattaca tcagtgtctg aggttaatac agcgaatgat ttgggcatag atgttataat
    15121 tacagaccat catgaatgtc aaagtgaaat tccatcagcc tttgcagtaa taaatccaaa
    15181 acaagaagat tgtaattatc catttgattc actatgtgga tgtggtgtag catttaaaat
    15241 gattcaagcc ttgactccaa aagaagaatt taaaactagt atgtataatt atttggaaat
    15301 agtaacacta gcaactattt gtgatattgt tccacttata gatgaaaata gaataattgt
    15361 aaaaaatggt ttaaaatcaa tgaaagaagg caaaaatatt ggattaaggg agcttataaa
    15421 agtttgtggt gtagaaagtg ataagatagg ttcttctcat ataggttttg caataggtcc
    15481 taggataaat gcttcaggtc gattgggata ttcttactta ggagtagagc tatttactac
    15541 tcaatcacaa gaagaggcag tagaaatagc tagtatattg gaagaaaaaa ataatgaaag
    15601 acagatgata gaagctaaga tgtatcatga agctgaagaa atgctaaagt ctaatagcag
    15661 atacaatgat gacaaagtgt tggttttagc taaagagggt tggcaacatg gaataatagg
    15721 aattgtagca tcaaagttaa ctgaaaaata ctacaaacca acaattcttc taggtataga
    15781 aaatggggag gctactggtt cagcgaggtc aataaaagga tttaatatat ttgaagctct
    15841 cataaagtgc aaagacttga tgactaagtt tggtggtcat gaacaagcag cagggttatc
    15901 cttggattca gacaatgtag aaattttagc aaatgaaata aataaatttg cagattataa
    15961 tttaactgaa gatgatatga tagagaatgt aaatgttgag tttgaattac aagaaaatgt
    16021 aataaattta aatcttgtag aagaattaca taagttagaa ccctttggat taaataatcc
    16081 taatcctaga tttatagtta gaaattatat tttaaaagat ttgaaagtta taggtaagaa
    16141 tcaacaacat ctgaaattaa gtatagaaaa agagaaaagc tatgaatgta taggatttaa
    16201 tatgagtcat ttaaaatcaa tgtataaagt aggagacaag gtagatgtat tattccaatt
    16261 agatgaaaat aactatatgg gaaataggaa agtacaattt ttacttaaag atatacgatt
    16321 ggctcgacct aaaagtgcaa gtaatgacaa actttcattg aaattaatgt caaaaataat
    16381 accaaaagat actcaaagcc tgtataatat atctgtgtct gattttgaat tatttgatgg
    16441 aaatacagat ataaatatat ttgattattt tgaaaaagat acactaataa tatctaattc
    16501 tataaatgga ttttatagag caatgtcaga tatatcactt atagatttgg attttaacat
    16561 aaattacaat attattgaag atgatagcaa aaatactgat aaattagagc ttatattttc
    16621 tcctaatatt gataaaatag acttaaaaag atataataat attattcttt atgattattt
    16681 atacaataaa ggcgaatatt cgtatatata tgagaataaa agagaagaaa gtgaaattat
    16741 aaaatattat aataaaacag acctattata tttaaagaat gtagttagta atatagttcc
    16801 atcaagagat gaatttataa caatttataa acaagcactc ataaaaaaag aaattgattt
    16861 ggatatggta aatataaggg aaacttttaa tgtaattcca ttaaagtttt ttacgatatt
    16921 aaatgtattt agagaattaa atttacttga ctttaattta aattatgaaa aaaattctgt
    16981 actcataaga atattgccaa aaccacagaa aaaattagac ttaaatgaga gtttaatact
    17041 caataatcta aaaaatttag aaaaacaata caatagcagt tattaggagg cgtttcccat
    17101 ggatttaaaa aactttataa ggaatattga tgatttccca aagccaggca tagattttaa
    17161 agatgtgaca actctattta aagatggaga tgcatttaaa tatgcagtgg attctatagt
    17221 tgaagaattg aaagataaag atgtagattt agtaatagga ccagaagcaa gaggattttt
    17281 gatgggcaca cctgtagcat atgctttagg agtaggattt gttccaatta gaaaacctgg
    17341 aaagttacca ggtgaagttg agagttatga gtatggatta gagtatggta cagatacttt
    17401 agagatacat aaggatgcaa ttaaaaaggg tcaaaaagta gcaatagtag atgatttatt
    17461 ggctactggt gggactatgg aagccgctgc caagcttgta gaaaaattag gtggagaagt
    17521 agtttctatg caatttttga ttgagctaaa attcttaaat gggagagaaa agttgtctaa
    17581 ctatgatgtt aattctctta taaaatacta gtacttttat aatagttggt ataacaccaa
    17641 ctattttcat atatattaaa attttataca aaataggtgg ttatatgcat gataaagaat
    17701 tacaagaaat aattgaaaaa ataaaagttt atgcacctaa tgcaaatttt gaaatggttg
    17761 aaaaagccta taatcttgca aaaaaagcgc atgaaggaca atatagaaaa tctggggaac
    17821 catactttat tcatccatta gcagttgcaa atattttaat agagatggaa ttagatattg
    17881 aaactataac agcaggttta cttcatgatg ttgtagaaga tacagaatat acctatgaag
    17941 acataaaaaa agaatttggc aaagaagtag cggatttggt tgatggagta actaaacttg
    18001 gtcaaataaa atatcgttcg aaagaagaaa ctcaatctga aaatttaaga aaaatgtttt
    18061 tggcaatggc gaaggatata agggttatac ttataaaact tgctgataga ttgcacaaca
    18121 tgagaacatt aaaatacatg cctccagaaa aagcaaagta taaagcaaaa gagacacttg
    18181 aaatttatgg tggtatagct catagattag gaatttccaa gataaagtgg gaactagaag
    18241 acagagcatt aagatttatg gacccagaag ggtattatga tttagttagt agagtatcaa
    18301 tgaagagaag tcaaagagag gattatattc aaggaattgt tgaacttctt aaagataagt
    18361 ttaaagattt aagtatacca tgtgatgtat atggtagacc aaagcatttt tacagtatat
    18421 atagaaagat gcaaaaaaaa cataagactt ttgaagagat ttttgattta acagcagtaa
    18481 ggatattggt tgataatgta aaggattgct atgcagtact tggtatagtt catacattat
    18541 ggagacctat tccaggaaga tttaaagatt atatagcaat gccaaaaccc aatatgtatc
    18601 aatcattaca caccactgtt gtaggtcctg atggagaacc tttagagata caaataagaa
    18661 ctcatgagat gcataatata gctgaaaatg gtatagcagc ccattggaaa tataaagaag
    18721 gtatctctag caaagaatca aaggttgaag aaaaacttca atggttgaga cagatgatgg
    18781 agtgggaaaa agatttaaaa gacccacaag agtttatgga tgcacttaaa gaagatgtat
    18841 ttaatagtca agtttatgta tttacgccaa aaggagacgt aattgaatta ccagcagaat
    18901 caacacctat agattttgcc tatagggttc atacaaatgt aggtaataaa tgtgtaggag
    18961 ctaaaattga tggaagaata gttcctattg attataagct tcaaaatggt aatattgtcg
    19021 aggtacttac atcatctaat tctaatggac caagtaggga ttggcttaat atagtgaaga
    19081 ccccaaatgc aaaaagtaga attagacaat ttttcaagaa ggaaagaaga gaagaaaatg
    19141 ttgaccgtgg aaatacaata ttagaaagag aatttaagaa gcatgatata ccacaaaaag
    19201 accctcttgt tgaaaaatat atggcattag ttgctaagaa atttaatcag ccaagtgttg
    19261 aggacttaat tgccactgta ggttatggtg gtataatgtc atctcaagtg gtatctaagg
    19321 taaaagacct atatttaaaa gaggttaaaa aagctaaaaa ggaacaacag atacaagaag
    19381 aagatttaaa taaacacaat ataagtgaaa cagaatacag taaaaagaga aagaaaaacg
    19441 catcacaagg aattatagta aaagggcttg acaatatctt agtaagattt gctaagtgtt
    19501 gtaatcctct tccaggagat gaaattgtag gatatattac taagggtagg ggagtagcca
    19561 tacacagagc tgattgccca aatgcaaaca ataatggtga tttcttccaa aatagattgg
    19621 tggaggtttc atggagttca gcaggaaaag gtaagtttga agcggaaatt caaataaaag
    19681 ctattgatag aagaggaatt gttaatgaaa taactcatat tgttgcaatg gataaactta
    19741 gtttaaacgg aataaatgca agaaaaggta aggatagtat tgtaagtata aacttacttg
    19801 tagaggttaa tgacacagag gaattaaaaa ttctaatgaa aaaattaaaa gcaattcctg
    19861 gtgtagaaag tatttataga atgacaaatt agagttaaaa taatagggag gaaactatga
    19921 gagcagtagt gcaaagagta tcttcatcta aagttacagt agatgaaaac actataggtc
    19981 aaataaataa ggggttacta gtattgttag gagtgactca tgatgataaa tcaagtgatg
    20041 tagattatat gattgataaa atattgaatc tgagaatttt tgaagatgaa aatgacaaga
    20101 tgaatttatc tctaatggat ataggtggag agcttttagt agtatctcaa tttactttat
    20161 atggagattg cagaaaagga agaagacctg gatttagtaa tgcagctaga ccagaacttg
    20221 caaataacct ttatgaagaa tttgtaaaaa aagcaaaaga taaaggtgtg acagttggta
    20281 caggtcaatt tgcagctcat atgatggtag agttaactaa tgatggtcca gtaacaatac
    20341 tattagactc aagtaaatct ttttaagggg gaaaacttta atgattataa aaaaatttgt
    20401 agatagttat tttggagtaa atacttatgt attaggtgat gaaaagacta aaaaatgtgc
    20461 agttatagac ccaggtggaa gtttagtaga gacattaagt tttgtaaaag aaaatgaatt
    20521 aaatattgaa tatattatcc ttactcatgg gcatggagac catataggat atgttaagga
    20581 tattaaagaa aaaactggtg ctaaagtagt tgcacatgtt gatgaaaaag aattattaaa
    20641 tgacaaaaat aaaaatctaa gttatacaat gagatgtgga gcacaagagt ttgatgcaga
    20701 tatctatgta aatgataaag acaagcttga acttggtgaa ttaaaaatga ctttcttgca
    20761 tactccagga catactcaag gatgtatgtg tataagagtt gaagatgaaa tgttcacagg
    20821 agatactttg tttgctggaa gtattggtag aactgattta tatagtggag actttaacca
    20881 aatggaaaaa tcacttaaga aattatgcaa atatgaagat gctgttagag tatatcctgg
    20941 acatggacca accagtactc taggggttga aaagaagaca aatccttaca tgtaatttta
    21001 tattagtatt taaaaaagta taaaatattt aataactata ttagtgaggg ggttcttcta
    21061 ctgttaaata gaaggagtta agttgatgtt gtatgttttt ttaaaaggac atgattataa
    21121 gtatgaagta gcagaactta taaaattatt taccagtgaa tttaagttta aagactctaa
    21181 tgctgacaat aatatagagt caaagcattt aataaataga ttgatttatg agaatggtgt
    21241 attattctca agtactgaat actatgaaaa tggaaactta aagtacgagt caatacagaa
    21301 tatagaaaat atgaatcttg aatttttaga tggatttgat agtagcaaaa cgattgaaga
    21361 atttcttaat agcctagata gtgaaagtaa gaggaacttt aaaaagctgt gtaaagaaaa
    21421 tatcaaaaaa agcatgtttg tagtgcttaa acaagtattt aattcttatg taccatgggg
    21481 aattttgact ggtattagac cagtcaaaat tgtccacaat ttaatggata aaaagctaga
    21541 tgataatagc ataagaacca ttctaaaaga taattatttt ataatagatg agaaaataga
    21601 tttagctctt gaaatagcta aaagagagcg attatttatg tatcctatag ataaaaataa
    21661 aatttctctt tatgtaagta ttccattttg tccaactaga tgtgtatatt gttcatttcc
    21721 ttcaaattca ttaaaacaat ttggacattt aaaaagagaa tatgtttata aattgattga
    21781 agaaattaag gggtttgcca aagttattaa ggatactaag aaagaagttg aaactctata
    21841 tattggtggt ggaactccaa ctacacttga tgaggaagaa ttggatttgc ttataaattc
    21901 attgttcaat gaattagatt taagtaaaat taaagaattt actgtagaag caggtagacc
    21961 tgacactatt acagaacaaa aactaagagt gttaaaaaaa cacaatgtta gtagaattag
    22021 tataaatcct caaactatga atgatgatac tttagtaaag attggaagag agcatagagt
    22081 atctgattta gtagattgct ttaatatggc tcgtagaatg ggatttgata atataaatat
    22141 ggatataatt ttaggtctta tagatgaaga cttaaatatg gtaaagaaca cattggagga
    22201 gataaaaaaa ctttctcctg aaagccttac agttcataca ttagccataa agagagcatc
    22261 caacttaaat ataaatatgg ataggtataa agaacatcta acacaatatg aagaaatggt
    22321 aaaaatgata gatttatcaa tgaaatatgc aaaagatatg ggattaaatc catattatat
    22381 gtacagacaa aaacatatgt tgggaaattt agaaaatata ggttatgcta aagaaggata
    22441 tgagtgcatt tataatatac agattatgga agaaaaacaa agtaactatg cattaggtgc
    22501 aggtgctata tcgaaatttg tttatgtaga tgaagataga attgaaagag tagaaaatgt
    22561 aaaaaatgtt gaacaataca ttgaaagagt agatgaaatg ataaaaagga agaaagaaga
    22621 ggtatataaa aatgttgact aaagctccta gaggaactaa agacataact ccaaaagagg
    22681 cttacaaatg gcgttatgta gaaaataaat ttagagaaat atgtgcttta tatggatatg
    22741 aagaaatggt aacacctata tttgaacata cagaactttt caagagaagt gttggagata
    22801 ctacagatat agttcaaaaa gaaatgtatt cttttaaaga taaaggtgat agagaaatta
    22861 ccctaaagcc agaaggtaca gcaggtgtag taagagcatt tatagaaaat aaattatatg
    22921 cagatactca accaacaaaa ttattttatg tgacaccttg ttttagatat gaaagaccac
    22981 aagctggtag acaaagacaa tttcaccaat ttggaataga agcacttgga agtgatactc
    23041 cttcaatgga tgctgaaata atcgcactag ctgttcaatt ttttaatgaa gttggattaa
    23101 atgatttggt agtgagtata aattcagttg gttgtccagt ttgtagaaaa gagtacaatg
    23161 ctttattaaa agagtatctt gactcaaaag ctgatatatt gtgtgatact tgcaatgaga
    23221 gaagagaaaa aaatccaatg agggttatag actgtaaaaa tcctacatgt aaagaaaata
    23281 tcaaagatat accatttatt gcagaccatt tgtgtgatga ttgtaaatct cactttgata
    23341 aacttcaaga atacttaaag gaaatgaata taaactttgt aattgataaa acaatagtta
    23401 gaggcttaga ttactataga aaaactgctt ttgaaattat atctaatgat ataggagctc
    23461 aaagtactgt atgtggtgga ggaagatatg atggtcttgt tgaacaatta ggaggaccaa
    23521 aaggtataag tggaattggg tttggactag gaattgaaag acttttactt acacttgaag
    23581 gtaatggaat tgaaatagaa aaccctcaat ctacggatat atttatagta actataggtg
    23641 aagaagcaaa tacaagaagc tttaaattgt taaaagactt gagacaaaat catataagtg
    23701 cagataaaga ccatatagag agaagtgtta aagcacaatt taaatattca gataaaataa
    23761 attcaaaatt tacaatagta attggagatg atgagcttaa aaatgacact gcgacattaa
    23821 aaaatatgaa aacatcagag caaactactg taaaattaag tacattagtt gaagaattaa
    23881 agcaaaagct gtaaaataag aaagtatgat gttttgtgta ttagataaat atatagcatt
    23941 aaaattaaat aaaatggagg tagtatcttg gaaactttaa agggtttaaa gagaactcac
    24001 tactgtggag agttgagaga aaaaaacata aatgaagaag tcgtacttat gggatgggta
    24061 cagaaaaaaa gaaatttagg tggtcttgta tttgttgatt taagagatac aagtggatta
    24121 tgtcaaatag tttttgatac agatgtagat aaagaagctt ttgaaaaagc tgaaaaatta
    24181 ggggctgaat ttgtaatagc tgtaaaagga aaagtatgcg aaagacaatc taaaaaccct
    24241 aatatgctaa ctggtgatat agaaatattt gcaactgaac ttagactttt aaacaagtca
    24301 gaaactccgc ctatttatat aaaagatgat gatgatgttt ctgaagcact aagattaaaa
    24361 tatagatact tagatttaag aaaaccatct atgcaaagaa atttaaaatt aagacataaa
    24421 gtaatgaata ttacaagaaa ttacttatca aacaatagat tttgcgaaat agaaacacca
    24481 tttttaatag ctccaacacc agaaggagca agagattatc tagtaccaag tagagttaat
    24541 ccaggaaaat tttacgcatt accacaatca ccacaattat ataaacaatt attgatggta
    24601 agtggtatgg atagatattt ccaaatagtt aaatgcttta gagatgaaga cttaagagca
    24661 gatagacaac cagagtttac acaaatagac tgcgaaatgt cttttgttga gcaagaagat
    24721 gttatgagta tgattgaagg tttgcttgaa gcgatattta aagaagtttt agatgtagaa
    24781 ttggcacttc cacttcctaa gatgacttat gcagaagcta tgtctaaata tggttcagat
    24841 aaaccagata ctagatttgg atatgagtta acagatatat ctgatgttgt ttgtaactgt
    24901 ggatttaaag tgtttgctga tgctacacaa ccaggaaaaa gtgttagagg tataaacgta
    24961 aaaggcaaag ctgacgactt tactagaaaa caaatatcat cactagaaga acatgctaag
    25021 acatatagag caaaaggtct tgcttggatg aaagtaggac aagaaggagt aacttctcca
    25081 atagcaaaat tctttaatga agaagaaatg aacgctatac ttacaagaat gaatgctgaa
    25141 gtaggagatt tacttttatt tgtagctgat aaaaactcaa tagtatttga tgctttagga
    25201 caagttagac ttgaagtagc aaataggctt aatctattgg ataaaaatgt atataactta
    25261 ctatgggtaa ctgagttccc agtttttgaa gaagatgaag aaacaggcac attctcagca
    25321 atgcatcacc catttacatc acctatggat gaagatttag acaagttaga agaaggtgat
    25381 aagtcatctt taagagcgaa agcttatgat attgtattga atggttatga aataggtgga
    25441 ggaagtgtta gaatatcaaa ttctgatgtt caatcaagaa tgtttaaagc acttggtttt
    25501 acagaggaaa gagctaatga aaagtttggt tatttattag aagcatttaa atatggtact
    25561 cctcctcatg ctggtctagc ttttggtctt gatagacttg ttatgttact tgcaggaact
    25621 gataatataa gagaagttat tgcattccct aaaaatcaaa atgctgtttg ccctatgaca
    25681 aatgctccta cattggcgga agatgagcaa ttagaagaat taagtataaa agttgatata
    25741 aaagataatg aataatatgt agttgcaaga aactaaaatg taaaaagtct ggatataaaa
    25801 tatatttata ttcagacttt ttttattaga attattttat attttttctc tatatatttt
    25861 cataaattat acttatattc ttaaccaata taattaaaat actatgttta aaaattttac
    25921 ataaacttga ttattttaga aactacttct gtaatgagta cacgatttta attaaagaat
    25981 atataacaaa tttgaaataa gtctaatata tgacttaata gattaaatta aaataataaa
    26041 tttggactat ttatctattt ataacttaaa ttatatcaaa ttgataacaa actagatatt
    26101 atactttttt gtagaataga attacaatta tataaagaaa aattctatta atagtgaaaa
    26161 aaaagtagaa aaaagtagaa attattcttt tataaagaaa gggagggata atattgcaag
    26221 agagagaaga attagtttta aatccagttc caaaagagga aagagttgga tggttagctc
    26281 cattgtttaa tatgcttggt tctaacatag ctatatctga actaatggtt ggaggaactt
    26341 taattttagg aatgactctt tctaatatga ttattacatc aattataggg aacttaatat
    26401 tagttgcaat tattatgata caaggttata taggttacaa agaagggtta aatacgtatg
    26461 tattagctaa gggggcattt ggagagatag gaggaaagta tcttatatct ctattacttg
    26521 gtataactag ttttggatgg tttggtgtac aagcaggggt tgcaggacta tcagtacaaa
    26581 agatatttcc aagtgtaaat ctaacattag ttacagttat acttggatta tttatggttg
    26641 tttttgcact gtatggcttt aaagctatgg ctaaatttaa ttacttagtt ataccaccac
    26701 ttatgatatt aatggtgtgg ggagttttta aagctttttc tacttatgga gttgaagcta
    26761 tttataatta tactcctcaa acaactatga gtatggttga aggtcttaat attgtagtag
    26821 gtcttgttat agttggtgca attatatcac ctgaccagtt aagatatacg agacgagtaa
    26881 aagatatttg gattatcagt tttttaggtc tagggattat ttcattattc caacaagttg
    26941 cagctggtgt aatgtctatg ggagcaccta cttgggatat aacagaagta ttggctaatt
    27001 taggttttgg atgggtagcg tttgttattt taatacttgc atcttggtct acaaacgtat
    27061 caaatgctta ttctggtgga ttagcattaa aaactatttt tccaaatgta aaaagaaatg
    27121 ttttgacttt agttgcaggt ctaataggta caataatagc agctactggt ataatattta
    27181 aatttcagtc atttttatct ttcttgggaa tcgcagttcc tgcaatagct ggaattatgt
    27241 ggtgtgagta ttattttata caaggaagaa cttataagca tagagaagga ataaattgga
    27301 ttgcagtaat aagctggtta ataggttttg cagcgtcgta ttatagttca aaaataaatt
    27361 tcttaatacc tccgataaat ggaattgtag tgagtatggt tatttattat atattaatga
    27421 aatgttttgg aatcaaagat aaataaaggg ggcaattaca tgggtcgtaa ggtgaaaata
    27481 ggtataattc aacaacacag tgtacttgga gatgttaaaa aaaatataga aaaggcagta
    27541 gagatgatag atgacttagg aaaacaaggg gcagatataa tttgtttacc agaactattt
    27601 gctacaggat ataatttaga gtctttaggt ggagttaaaa cattagaatt aataagagaa
    27661 cataataagt acatagagga atcaatgtca gaagctgcta aaagaaataa tgtatacctg
    27721 atatctccat atggaacctt agaaaaaggg tctacacatg tttataattc agcagttata
    27781 tttgatagaa aaggtaagat tatgggagaa tactgtaaaa atcatctgtg gtcattagaa
    27841 gcagtatact ttaaaggagg ggaaaaagta gaggtatatg atgctgattt tggtagattt
    27901 ggtgtaatga tatgttatga tgcaggtttt ccagaagtat ccagagaatt gacattaaaa
    27961 ggttctgaaa taatatttat accatctgca tggagaatac aagatgaaga tatgtgggat
    28021 ttaaatgtat ctcaaagagc tttagagaac actgtatata cagtaggtgt aaatttagta
    28081 agtaatgact ctaatttaat actatttgga aagagtaaaa tatgcaatcc tagaggtact
    28141 gtaataactc aattagatac atacagggaa aaatatgtat tatcagagat tgatttagat
    28201 gaaataaaaa agtataggga agatatcccc tatttgaaag acagaaaaag tagctataac
    28261 atataattct atactataat acaagttcaa tataaaatga taaaaagagg atgtatcaat
    28321 attaagatta aatttattat actttgatat atcctcttta atattatcaa ctttgattta
    28381 aatattttta aaatagttga taagaaagtt tttgaacaac aacacagctt tagattcata
    28441 gttttcgcta aaccatgaaa gatttaaata tcttttaaat tcaatatctt tgatatgtaa
    28501 caacttaatc tcagggtctt gagataatcc ccatgatttt ccacatataa atccaactcc
    28561 ttgaagtgat tttataagag cataaattgt atatggtgaa tcagactcaa atgctatttt
    28621 gggtttgaaa ttagctgatt cgcacaggat atcaattacc tctctataat tctcaccctt
    28681 cgttataact ataaagtttt catctgaaac ttcgcttaga tatacttcat cctttaatga
    28741 taaaggatgg tttattgaaa ctcctaatag tatttcttcg catgttaaag ttatgctatt
    28801 ttctgagttt agctttgtaa atgaagaaga tatgtacaaa tcaaaatcac tttttttata
    28861 agatgatggc aaagtatgtg acacattaaa agtaatattg ggatatagtt ttctgaaatt
    28921 actcaaaagt gatggtaaca cattagccgc tgcaggagat aatatcttta cttctcctga
    28981 attttctaaa gaagtgtctt gtaactcctt ttttgaactt tctactaaat ctaaaatgct
    29041 atctactctt tttagaaaca atcttccata ctcatttaaa acaatatatc ttccttttct
    29101 gtcaaataac tgaactccaa gttctttttc taaggaagat atagttttgc ttaaagctgg
    29161 ctgtgctata tttaacttgt gtgatgcttt tgttatgtgc tccattctag caacagtttg
    29221 aaaatactta agatgcaata aatccatagt ataaaataca cctcttttaa tatgacttga
    29281 gttatatcaa ttttataatc aactccacat tatacattat aatataaagt ttatataata
    29341 aactacaata tattaaaaag ttatttaaat tgttatttat attttgtaca taatctaatt
    29401 aaaaaaagta actttaaatg attaactaag gaaatgttgt tacaaacttt agttatataa
    29461 aaaattcatt tgatgagcaa agtactaata tcaagtaaga ataaaagctt attagataag
    29521 aaaaataata ttttataata atgatgttac ttaaattatt atgttatact attttaaata
    29581 ggaaaaattt agatactata attttagggg gagtcaagat gaaattaact aaatcaatat
    29641 catcaatgct gtgcttatct ctagttttaa gcttatcacc agtagcatat gcaaatgaaa
    29701 taagtagaac aacagttgag aatactttag taggtcagga tagatatcaa actgctgttg
    29761 aagtaagtaa aaaaggatgg agtagtgcaa atgaggctgt agttgtaaat agtgaatcta
    29821 ttgtagatgc attagctgta acaccatttg ctaaattaaa aaatgctcct atattattga
    29881 cagaaaaaaa taatctaaat tcacaaactg agaaagaatt aaaaagatta ggagttaaaa
    29941 aagtttatat aattggtcta tctagttctg tatcaaatga tgtgcaaaaa cagttagaat
    30001 ctaataattt aactactgat agagttggtg gtagtgatag ataccaaaca gctttgagta
    30061 tagctaaaaa aatagaagga ttaaaagata tatcagaaat agctgtagta aatgggtaca
    30121 caggtcttgc agatgcagtt agtataggtt ctgtagctgc tactaatgga atggttatac
    30181 ttccagtatc tgatgcatct ggtatatcta gctttaaaga ttttatagaa tctaagaata
    30241 taaataaatc atacataata ggctctacta atgctgtatc agataaaata aaacaaagtt
    30301 tacctaattc agaaagaata ggtggagcag atagaaatga aactaatggt aaagtaatag
    30361 aaaagtttta tacatctaat aaattaaaca atgtatttgt ggctaaggat ggaatgaaaa
    30421 atcaaaatca acttatagac gctctagcag taggagtact agcatcaaaa gaaaattctc
    30481 ctgtactaat cgtaggagaa caattaagtg caacacaaaa gagtgtattt tcgaataaaa
    30541 atgctacctc tataactcaa gttggtagtg gaggaaatga aaatgcattt aaagaattaa
    30601 aagatttaca ggcaaatagt aacaataaga gagtaatgta tgtaactaat acagataagg
    30661 taaatataag aaatgatgct acaatagaag cttctgttat aggatatcta aataatggtg
    30721 atgaagtaga agttttagat gtgttaaaaa ctggatgggt aaaaataaaa tacaatgaag
    30781 gtattggata tgttagtggg tcttatttga caaataataa gcctgataat agtaatgaaa
    30841 atataaaaat aaagtatgta aaagaaaaag atggtctaaa tgttaggaaa ggaccaagta
    30901 cagaagatga aaaaataggt cacctttcat atggaagcaa agtagaaaca atagaaatgt
    30961 ttgctactgg atgggtaaaa ataaagtaca atggtggata tggttatgta agtaatgatt
    31021 acttatctga tacaccagtt atttaattat aagtaacaat aaaaaaactg ctttaatttg
    31081 taaagcagtt tttttataaa aatttaagtc taataactat ttctattttg ataccttaat
    31141 cctgggattt attattatgg atattatcaa catacaaaca ctccaaatcc agtgtctaat
    31201 tccaaactta gatattaata aattcagtcc tgctatggta aataagcagt atttaattac
    31261 aattaaaagt gtatttatag aaagccccct catagaaagt atcctaaatc caataataga
    31321 cattctaagt cctataaatg ccaataatat acctgcaata tcctgaatta agtaatagta
    31381 ttcaaatttc atattcaatc aactcttctc tgagcagtat caaatatttc taactcttca
    31441 atttcatcat ctgtgtatgt aagcatagta aaaccagtta caccataaat aaatgaaatt
    31501 ataggtgtaa tccaacttaa gaaacaatat ggaataaatt ctagtggact tacaccaaga
    31561 gtctgagcac agaaaacagc atttgaattc catggtatta atggaccacc aagtgtagct
    31621 gtatcttcta taattctaga tagattttgt ggttttaatt taaattcttt gtatattgga
    31681 gacattagag ttccgacaaa tacagaagtg aacatcattg atgaactaaa tgcatttgca
    31741 aagtagctta ctataaaagt agacccaacc aatttagttc ttgattttcc tattttagtt
    31801 ataagaggtt gaagcagtac ttctaagaat ccagtttttt ggagaatacc agcaataacg
    31861 aaaactacaa atactagtaa aacggtttca gccatactca ttattccacc acgatttaat
    31921 agtttgtcgg catagacaaa tccagtatct atagtaaatc ctgatagcat gtaatttaaa
    31981 acatcaccta ttttttctcc ttcttgaaat actgctataa taagtcccat gatagctgaa
    32041 cttagtatag atataatggg tggcttttgt agcaataaaa gtaataataa aaatattatt
    32101 ggaatcattg ctactaaacc aatatgaaag tttgaattta atacatcctt gatttgattt
    32161 atttgaacat agtctatagt attatttgaa tacttaaatc caattactgt atacagaact
    32221 atacatatta cgtatgcagg tcctgtggta taaaacatat gcttcatatg tgtaattaca
    32281 tctgtcttac aaactgctgc agctaagttt gtagaatctg atagaggtga catcttatct
    32341 ccaaagaaag caccagaaat gactgcacca gctgttaaac caagaggaat acccatacta
    32401 gtaccaatac tcatcattgc tataccagaa gttccaagag tcccccaaga tgtaccagta
    32461 gcaacagaag ttaatgaaca tacgattaat gttgtaagca gaaaatattt aggggttatt
    32521 attgttagtc cactatatac tactgttggt attgtaccag cagctatcca agctgctatt
    32581 agtacaccaa cagaaagtat aattaagttt gattgaaagg catctttgcc aacttcaaat
    32641 ccaaaagctt ctatttcatc attagtataa ccaagtttca tggctgcagg aactactata
    32701 agccatgaaa gtaaaaacat tgtagttata gaagcattaa atacaactat accaactgat
    32761 gttagagcta ttattgcaag cattactaac aaggaatatc taaatgaagg tatttttctt
    32821 tctgtattca ttttcatagt gcaaattctc cttaaatatt tttagttaat tgcatttttt
    32881 attcttataa gagcttcttc aagcatactt cttggacaag ctaagtttat tctttgatac
    32941 ccacttcctc caatgccaaa gctgtttcct tgatttagag caactttacc tttttgtaca
    33001 agtatacttt ctagttcctc atcacttaat ccaagtgcac taaagtctac ccataataaa
    33061 taagtacctt ctggttttct aactttaagt tttggcatat tttcatttat atattttata
    33121 gcaaaatcta tattagattc taaatattct aaaaatgatt ctagccaaga ttcaccatta
    33181 ttatatgaag cttcagttgc aactaagcta aagcaattat ttctctttat atcaattctg
    33241 gtaaaggcat catctaacaa tttatagtat ttttcatcag gtagtattac atatgatgat
    33301 tgaagaccag ctatattaaa agttttagtt ggagccatac aagtaattgt atttttttca
    33361 aattctttag aaatagatgc cataggaata tgcttatgtt tttttaatat aatgtcacta
    33421 tgtatttcat cagatatgat ttttacatta tgcttaagac aaatatctcc tagttttttt
    33481 aattcatctt ttgtccatac tctaccaact ggattatgag gattacaaag tatgaataat
    33541 tttacatctt taatcttgtt ttcaatgtct tcataatcca ttatgtagtt tccattttct
    33601 aatttttgta atgggcttat aattagttct ctattgttat tttttacaac actattaaaa
    33661 gggctgtaaa ctggttcttg tatcattatt ttatcatttg cttttgtgag ttcatttatt
    33721 aaaagactta tagctgggat aacacctgga ctataaatta accactcact ttttattttc
    33781 cagttatgtc tcctatctag ccagtttact atagattcat tgtaagaatc tggtcttgtt
    33841 gtgtagccat aaatctcttg ttctagtcta ttttttaaag aatcaattat acaaggtgca
    33901 gccttaaaat ccatgtcagc cacccacata ggaagtaaat cattagttcc atactttttt
    33961 tccatttctg accatttaga tgaaaaatta ttgcttctat caacaatctc attaaaatta
    34021 taattcattg taaatacctc cagtaatttt aattttatgt taataatatt aagcaaacaa
    34081 cgtgccaata ttgataataa aaaatattta ttcacaagtt aatatttaat attaagtaat
    34141 ttcagagcat agataagata aaaatattaa ttatacttaa aactttgtgg aaaaggttat
    34201 ttctaataaa tttttaaata tatgaaaatg taattaaata ggttaaatag gtttaactgt
    34261 ttaacttgtt agacctattt atatttttta gaaactctac tccctttgat gttataattg
    34321 aacctccacg accaacaagt atgtctacaa gcccaaagtc ttgtagttct aaaagcatat
    34381 ttctaatctg ttgttctgtc aaaaatctat tttcctctaa agctatttta cataagcttt
    34441 ttctacctat tctttctttt aaatcataag ccttttttaa attatccaat ataaatatgt
    34501 attcatctag tgacctttta aaattatagt cgtatttcat gatgtttttg tctttgccaa
    34561 tgttgaattg atactttttt atattattac ttactttatt acaaacggtt ctactataat
    34621 ttgaatctat agtatctaat atatattcag gtaaatcaca tatttctata atatcttttt
    34681 ccaagtaaca gaaatattct cctaagtttc ttaattctct tacatttcct tcccatctat
    34741 acattttaaa gatttctttt acttcctcac ttagaataaa attacatgga atatcatatt
    34801 ttaatgaacc aaaaatttca aatatatcag caggtctttc cctaagtgga tgtattttaa
    34861 ggggaagaac attcaaccta aaatataaat ctcttctaaa catattttta gatacaagtt
    34921 cttttaaatt tctattagta gctgcaatta ttcttacatc aatgtcaatg acattattag
    34981 aaccaatacg tcgtacttgt ttttcttgta tgactctaag taatttagat tgagaattta
    35041 aatccatttc tccaatttcg tctaaaaata tagttccatt gttggctaat tcaaataaac
    35101 caattttccc acctttttta gcaccagtaa aagccccttc atcatagcca aataattcac
    35161 tttgcagtag attttcttga aaagtactac aatttactgc gacaaaagga ccatcttttc
    35221 tcctagaagc actatgaatg gattgagcaa ataattcttt accagtacca ctttcaccaa
    35281 ttataaggat agatgaattt gattgagcca ttttattagc aatttttttt gtattaatag
    35341 tttgtatact agaacctaat atatcatcaa atgtgtattt actgatatta ccagagttta
    35401 ctagttgtgc tcttaattta gcttgctttt tttctaattg agaaaacttt gtcatcttta
    35461 gtataaatcc atcaaataca tttaattgta tatgtttaat ctctaaattt atatcaatat
    35521 gatttatttt aatcaatttc tcaaaaaatg gagttttatt ggtcaatatg ctttgaaaat
    35581 tgatgtcttt tatgcaatca ccaacaaatg agtcaatcat ttcatttgca tttatagaca
    35641 aaatttttct agccatatga ttatagaatt gaattattcc atcgttattt gtgcatataa
    35701 ttccatcatc aattatagat agtaacaaat caaattgtct ttcaaactta tttgcatcta
    35761 acaataactc acctgtacta taacttgtag gaattatttt ttctacgtat ttttttatta
    35821 ggtcatcttt tattagatgt tttaatttgg tttttgtagc aatttcaaca atacaactta
    35881 aatctattat tctgtatttt aaatctataa cttcacaatt tttaaactta ggcaagattt
    35941 tttcgccagg agttaggatt acagcatctg tgggagtaaa ctcaatctct ggatagcagg
    36001 gcaggatatt tatattgtct attcctaatc tatgtattaa agaaattgtt tctattgcca
    36061 tatctttact taagttatat acataaataa ttttatcttt ttctaatttg gatatcatat
    36121 caatactgtt cttttcaaat gtcaacttag gaacaatgat ttgagcatca tagtgagata
    36181 attttactat ttcatcatat tttaaataag cagataggag tataagtttt tctttaaaaa
    36241 actttaaatt tccttcttca aatgagtata aatttatctt tagattatca cctaagaatt
    36301 gtcttatttg attttcataa atttctccag cgtctttttt taaacttaca atagctaatt
    36361 ccatttgttt cattttaacc tctcatacaa atttgactta ttttagatta cataataat
//
LOCUS       DAEPXW010000037        34759 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.038, whole genome shotgun sequence.
ACCESSION   DAEPXW010000037 DAEPXW010000000
VERSION     DAEPXW010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34759
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.038"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(449..2836)
                     /gene="cadA"
                     /locus_tag="KRM55_001761"
     CDS             complement(449..2836)
                     /gene="cadA"
                     /locus_tag="KRM55_001761"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBH1594009.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2859..3224)
                     /locus_tag="KRM55_001762"
     CDS             complement(2859..3224)
                     /locus_tag="KRM55_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1594010.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3423..4271
                     /locus_tag="KRM55_001763"
     CDS             3423..4271
                     /locus_tag="KRM55_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594011.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQATNIEE
                     FDEEEM"
     gene            complement(4708..5796)
                     /locus_tag="KRM55_001764"
     CDS             complement(4708..5796)
                     /locus_tag="KRM55_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594012.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYTINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5921..6649
                     /locus_tag="KRM55_001765"
     CDS             5921..6649
                     /locus_tag="KRM55_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH1594013.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6851..7342)
                     /locus_tag="KRM55_001766"
     CDS             complement(6851..7342)
                     /locus_tag="KRM55_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594014.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7353..7796)
                     /locus_tag="KRM55_001767"
     CDS             complement(7353..7796)
                     /locus_tag="KRM55_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594015.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7786..8625)
                     /locus_tag="KRM55_001768"
     CDS             complement(7786..8625)
                     /locus_tag="KRM55_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594016.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(8844..10229)
                     /locus_tag="KRM55_001769"
     CDS             complement(8844..10229)
                     /locus_tag="KRM55_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1594017.1"
                     /translation="MENLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(10402..11145)
                     /locus_tag="KRM55_001770"
     CDS             complement(10402..11145)
                     /locus_tag="KRM55_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBH1594018.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(11165..12427)
                     /locus_tag="KRM55_001771"
     CDS             complement(11165..12427)
                     /locus_tag="KRM55_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1594019.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEISEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIGGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKGLEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12611..13609)
                     /locus_tag="KRM55_001772"
     CDS             complement(12611..13609)
                     /locus_tag="KRM55_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBH1594020.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWGGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13593..15104)
                     /locus_tag="KRM55_001773"
     CDS             complement(13593..15104)
                     /locus_tag="KRM55_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH1594021.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(15158..16120)
                     /locus_tag="KRM55_001774"
     CDS             complement(15158..16120)
                     /locus_tag="KRM55_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH1594022.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(16168..17058)
                     /gene="rbsK"
                     /locus_tag="KRM55_001775"
     CDS             complement(16168..17058)
                     /gene="rbsK"
                     /locus_tag="KRM55_001775"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBH1594023.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(17100..18113)
                     /locus_tag="KRM55_001776"
     CDS             complement(17100..18113)
                     /locus_tag="KRM55_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1594024.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(18342..19319)
                     /gene="bioB"
                     /locus_tag="KRM55_001777"
     CDS             complement(18342..19319)
                     /gene="bioB"
                     /locus_tag="KRM55_001777"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBH1594025.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEF"
     gene            complement(19525..19788)
                     /locus_tag="KRM55_001778"
     CDS             complement(19525..19788)
                     /locus_tag="KRM55_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594026.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19858..20931)
                     /locus_tag="KRM55_001779"
     CDS             complement(19858..20931)
                     /locus_tag="KRM55_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH1594027.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(21190..21948)
                     /locus_tag="KRM55_001780"
     CDS             complement(21190..21948)
                     /locus_tag="KRM55_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1594028.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISIVCLLAAVILFNKKPV"
     gene            complement(21945..22862)
                     /locus_tag="KRM55_001781"
     CDS             complement(21945..22862)
                     /locus_tag="KRM55_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594029.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDGGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(22862..23062)
                     /locus_tag="KRM55_001782"
     CDS             complement(22862..23062)
                     /locus_tag="KRM55_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBH1594030.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(23067..24161)
                     /locus_tag="KRM55_001783"
     CDS             complement(23067..24161)
                     /locus_tag="KRM55_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594031.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24671..24811)
                     /locus_tag="KRM55_001784"
     CDS             complement(24671..24811)
                     /locus_tag="KRM55_001784"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBH1594032.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDTYPDSGWGFMTWDEN
                     GE"
     gene            complement(25121..26428)
                     /locus_tag="KRM55_001785"
     CDS             complement(25121..26428)
                     /locus_tag="KRM55_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1594033.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVSGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(26493..26972)
                     /locus_tag="KRM55_001786"
     CDS             complement(26493..26972)
                     /locus_tag="KRM55_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBH1594034.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(27019..27882)
                     /locus_tag="KRM55_001787"
     CDS             complement(27019..27882)
                     /locus_tag="KRM55_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1594035.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(27882..28637)
                     /locus_tag="KRM55_001788"
     CDS             complement(27882..28637)
                     /locus_tag="KRM55_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1594036.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28664..29152)
                     /locus_tag="KRM55_001789"
     CDS             complement(28664..29152)
                     /locus_tag="KRM55_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1594037.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(29170..29571)
                     /locus_tag="KRM55_001790"
     CDS             complement(29170..29571)
                     /locus_tag="KRM55_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBH1594038.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29574..30071)
                     /locus_tag="KRM55_001791"
     CDS             complement(29574..30071)
                     /locus_tag="KRM55_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1594039.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(30095..30499)
                     /locus_tag="KRM55_001792"
     CDS             complement(30095..30499)
                     /locus_tag="KRM55_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1594040.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30729..33296)
                     /locus_tag="KRM55_001793"
     CDS             complement(30729..33296)
                     /locus_tag="KRM55_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1594041.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLLKFIFHCSCMIERVIVKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            33462..34205
                     /locus_tag="KRM55_001794"
     CDS             33462..34205
                     /locus_tag="KRM55_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH1594042.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHNNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKDKLLDVDYTNI"
BASE COUNT        11264 a         6369 c         3561 g        13565 t
ORIGIN      
        1 tatatcacct taaaaataat tcgtcaatac tttttaaaat tattttttaa aaatatttac
       61 tttcttatat tacataattt attgaatggc agtcatactg ttggtttaga gtattttaac
      121 acacacattt tgttgtaaaa attacaacta ttaatataat atatatacaa tcataagtat
      181 tataattttt atgaatctaa tttaaactta atataaactt attaataaac cttctatgtc
      241 taaattttaa aattacaata taaaagctct acactaaata aatacattaa ataaacataa
      301 tggataatga atataaattt atatatgcaa agcgctccaa taaaaaggta ccaataaagt
      361 taaaagaaac ttattgatac ctttcattat tacatacttc aatatataat tataagtttt
      421 ttaaatagta tggatttaca tttatccctt atctcatagc tctcatagca tttactactg
      481 ctataagtgc cacacctaca tcagcaaata tagcttccca catagtagct actcctccag
      541 cacctagtat cataactata atttttactc ctagagcaaa tattatgttt tgccacacta
      601 tcttattagt cttgtttgct atttcaattg ctttagatat cttgctaggc tcatctgtca
      661 taagcactac atctgcagct tcaatagcag catctgaacc taagcctccc atagctatac
      721 caacatcagc acgagctaat actggagcat catttattcc atcacctaca aatgctattt
      781 tctctttttc agttcttcct tcatataaat cttctaatct atctaccttt tcattaggaa
      841 gtaaatttga gtaaactgta tccaattcta attcttgagc aatatttttt gctactttct
      901 cattatctcc agttaacatt acaacttctt ttacccctat ttcttttaag cttcttatgg
      961 catttttact atcttctttt acttcatcag agataactat ataacctcta tatactttat
     1021 caacagcaat atagactact gtgcctactt ctttagctga tgaataagat atattttctt
     1081 ttttcataag tttctcatta cctgctaata taaaattgcc attatgcttt actctaattc
     1141 cataagctgc tatttcctca taactgtcta ttgtatctaa atcaattttt ttattatagt
     1201 aacttaatat ggactttgct attggatgat ttgaatttac ctccgcaata gctgcatatt
     1261 ctaataattc ttcttctgat ataccttcag gatttaactt agttacattg aacacacctt
     1321 tagtaagtgt tcctgtttta tcaaatacta ctgtatctac acttcttaaa gcttctaaat
     1381 agttacttcc tttaataagg ataccatttt tagatgcaaa cccaattcca ctaaagaaac
     1441 taagtggtat tgataaaact aatgcacaag ggcaagaaac gactaagaat atcaatcctc
     1501 tatataacca atcactaaat acctcacctg agattacaag tggtggcaca aatgctatta
     1561 ataaagcagc tattactact attggagtat agtatcttga aaacttagat ataaagtttt
     1621 ctgtctttga ttttttaatg ctagaatttt caacaaggtc aagaatctta gaaactgttg
     1681 attctccaaa actctttgta acttcaatac tcaataaagc atttttattt ataacacctg
     1741 ataagatttc atctcctttt tcaacttctc tcagcactga ctctcctgtg agtgcagaag
     1801 tatctaacat agaaactcca tctactacta caccatctaa tggtactttt tcaccaggtt
     1861 ttactactat tatatcacct acatttacct cttctggtga caccacctta acttcagaat
     1921 taacttttag atttgcatag tctggtctta tttgcataag tgaagttata gactttctgg
     1981 atttaccaac tgcaacacct tgtaaatact ctcctacttt atagaaaagc ataaccccta
     2041 ctgcttctga taactcccct attgctaatg ctcctactgt tgctagagcc atcaaaaagt
     2101 tctcatcaaa tactcttcct tttgatatat ttcttattgc tcttaaaagc acatcaccac
     2161 ctactattac ataggcaact ataaatacta tattgctaaa ctgactttca taacctgtag
     2221 ctgtttgata tataccaaat atatatacaa gtgctccaat tataagtgga attaattctt
     2281 tcttatttgt atcatttaca gctcctgatt tttcagtagt tctccctttt actttgtcag
     2341 tagaccctac ttgtatatca agccctggct ctgttgaatt tattatttct tttattttat
     2401 ttataacatc atcctcttca aagttattac ttatatttac tgtaagtttt ttatttacaa
     2461 agtttaaatt agaagattca acttctttta atttagaaac tttgttatta atctcttctg
     2521 cacaatgagc acagtttaat cctcctaata taagctcttt tttaattgat gttttactag
     2581 ctgcattttc tttagaactt atttgtatat caagacctgg ctctgttgaa tctattatat
     2641 ctattatctt ttctatagta gtatcctcat taaaactttc ctttatattt actgtaagtt
     2701 ttttatttat aaaatttaaa ttggaagatt taacttcttg tagtttagaa actttattat
     2761 taatctcctc tgcacagtga gcacaattta atcctcctag tataaattct tttttaattg
     2821 aattatttgc ttccatatat attcactcct ctcatttatc atttataagt ctctctaata
     2881 tgatttaatc cacaatcaaa tatctgactt atatgactat catctaatga gtaatacact
     2941 gtttttcctt ctcttctaaa ctttactaat ctagcctgct ttaatactct aagttgatga
     3001 gatattgcag aatgagtcat atttaataaa ctcgctatat cacatacaca catttcattt
     3061 gcaaataatg catataatat ctttactcta gtagtatccc caaatacttt aaataattct
     3121 gctaaatcat ataacatttc ttcatctggc atagttgatt tagcctctgt tactatttct
     3181 tcatgtacta tattacaatt acaatcattt atctcttctc tcatttttaa tcctccatta
     3241 ttttaatata tgaataactg ttcatatgtt cattatatgt tatcatttct aaatttgcaa
     3301 caataatttt tattaattta atataaatag aatgcacata ttataaactt ttttaatata
     3361 tatattatta gaataagttt ttgtaaactt ttttatagtt ttctaggagg tgcaagttta
     3421 atatgagtaa caagaaaaaa aaggatttag atactagtta catgccttac ttagacccag
     3481 cgaactatgc agattatatt actaatgaag aaattcccca agatgaattg agaaatgacc
     3541 ctcaaatttc taatggttat acaaaaatac ctaataacca gaacataaat aacctatatc
     3601 ctaataatgt aaatcattat cctaaaagta gtaattctcc aaacaacttg cctaacacaa
     3661 ataatacatc cggaaatatg aattacaata catctgctac aaataatatg cctaataaca
     3721 tgaataataa tacgggtatg cctaataata tgtctaacaa tatgaatagt aatatgggta
     3781 tgcctaacaa tatgcctaat aacatgaata gtaatatggg tatgcctaac aatatgccta
     3841 ataatatgaa tagtaacatg ggcatgccta acaatgttcc taataacatg aatagtaata
     3901 tgggtatgcc taacaatatg tctaataata tgaatagtaa tatgggtatg cctaacaata
     3961 tgtctggcaa tatgaataac aatatgtatg gtaatacagg tatgcctaat aacatgaaca
     4021 gtaatatggg gtataatatg aataatacta tgggtattcc taacttctca tgtaatcaaa
     4081 atatgcctcc taatgtactt atgatgatac caggagttat atgtcataat acaatgcaag
     4141 gtatgcctgt agttatgcct agtactatgc ctcctaatat atatcctact ccttatggtt
     4201 ctagtaatat gtctatacaa ggtataccac aggctactaa tattgaagaa tttgatgagg
     4261 aagaaatgta atatatattt ttttaagtaa gttgtataaa acattaataa ttgaccataa
     4321 taataaatgt attcctcata atattccccc aatattatta taggtataga aagttgactg
     4381 aatatgcgct tattcggtca acagatatta acataatcta ataagataaa catagaaaaa
     4441 gtcagataaa atttaatttt atctgacttt ttcatttaaa aatgctctct tgtgttggtg
     4501 attcagaata gtatggtact cgtatttgag actaatattg gcaaacaaca taaagaaaaa
     4561 tataaatttt ttataataaa ctgtataaaa ttttaataat tgaccacaat aataaatgta
     4621 ttcctcataa tattccccca atattataga aataaattta agcgagatta aattcagtta
     4681 atctcgctta aataatgtct aaatttatta ttccaaaaaa tcatcaaaat ctaatgaacc
     4741 tgattctgca aaatcatata atgcattttg ctcaaagaaa aatttctctt caaatttaat
     4801 atagtcgcta taattagatt gacttatttc attgatataa ttgcaatcat tttcgttata
     4861 agtaccaata aaaaacttat ttcccattaa gtaatatata gctttcatat cattatttat
     4921 tgtatataca ttttctttta catggtcatt attaaaatta aatctagtaa agaatatacc
     4981 ttcattcata ttacttttta acagaaatgg attttctcta taaaatactc ctgcaaattc
     5041 ttcaggtgaa tttacactgt aaacacttac aaattcactt ttagaaatct catcaaatac
     5101 ctcaaaatca tacataggtt ctttatctgt cactaataga gaattaattc taaaaccagt
     5161 ttcataacac ttacttatgc aaaaagcaat tttacatata taatatccat cattatcttc
     5221 atataaagct tcacttatat atctgccttg acctttatca cttaccacgt ttttaagtaa
     5281 tgttccattt atattagtaa tgtgcatatt tgcaatctcg tcacttccag aaaagtactt
     5341 taaactttct ctatcccatg ctataaatct catggtcata tagtttataa attcaacttc
     5401 ctcgtcaact cttttacata ttttattgta taatttttct atagttaaat ctgttttata
     5461 gttttttata atatcaatat actcacattt atctcctggc aatagcttat cataataaag
     5521 attcttatta ccaaaataag atactaaaaa taaagattca tccttcgtta attcaactct
     5581 atctgaacca aatcctccca tcaatctttc ttcttccata taagcttctt cttgtgttgg
     5641 gttatttaaa ctcacataat ccgctaatcc taatccctct gcatctaata aaaaatattg
     5701 acaaaagtga ttgttttcat catctatcca atttattata agacctaaac tgcccataag
     5761 tctagaattt gtagcctttg caaaattaaa attcatatag tcacatcctt taaactctaa
     5821 aatacttgtt ttttaatata taaattatta tacatatatt ttaacaactt agatacaatt
     5881 tataatataa tataaggaaa tgattaattg aggtggtctt atgaaaaata tagcagcttt
     5941 ttttgatata gatggtactc tttatagaga ctctcttatg gttgaacatt ttaaaaaatt
     6001 aattaaatac gatataattg accaaaaaaa ttggtataaa catgctagag acacttttat
     6061 ggattgggat aaaagacaag gtaattatga tgattatcta ttagaaatat gtgaccttta
     6121 tgttgattca ctaaaaggat tagataaaac ctgtatcaac tttacaagtg accaagtaat
     6181 taaattaaaa gcagatagag tttataaata cacacgttca aggattgagt ggcatctaaa
     6241 tcaaggacac atagttatat ttatatctgg tagccctgga tttcttgttg aaaaaatggc
     6301 aaaaaaatat aatgtaaccg attttctagg aagtgattat gtctttgaaa ataatatatt
     6361 tacaggcaca gttattccaa tgtgggattc tataagtaag aataatgcta taaacgattt
     6421 tgttgtaaag tatgatttag atttatcaaa ctcgtatgcc tatggagata ctaatggtga
     6481 tataaatatg ctaaaaagag ttggaaatcc aatagcaata aatccaacaa aggaactttt
     6541 atctcaaata tcacttgatg aggaaatttc taaaaatgtt gagataatag tagaaagaaa
     6601 agatattatt tattctctat ctacagatgt aaatatagtg gatatttaat ttatactatc
     6661 tattttaaaa acttatatta tatctaatat ttatatctaa catataaaag ctttgactaa
     6721 aaatcaaagc ttttatatgt tgcactaaga atatattaaa tttagcttta tgctttaatg
     6781 tatattcata tatatcattt acacttatct aaactacaat ttcattaaaa ttaaatataa
     6841 aaatcaacta ttatttttta aatagcatct ttcttaacct attattgtaa taacctataa
     6901 aagaactgta aacatagtca tatactataa aggctatctc aaatgaacct ataataaata
     6961 tgtttattgg aatataaact attgttctta ataaaaaata caatataagt atcattatat
     7021 ttgcaaatac taatttcata aaatactcaa tatatataga cctatctttt tctataagat
     7081 attttacaat accatatatt ccaaaggtaa gtgaatatac aatccattga gacttacttg
     7141 ccatcactat aaatcctaaa actatagaac ctatataaaa agcgattcca ctcttaaagc
     7201 cccattccat tattacaatt gatactaaaa gtgatgctaa ccccataata aacaatgtat
     7261 ttacaggaat aatatttgta agagtcaaca atatcacatt taatgctaat aaaactcctc
     7321 cataagcaac ttttatactc atatttatca tcctaacaac aagttattaa atctccacca
     7381 aaacattcac aacatgaatc taaacaccaa agtttagcac aattttcaca acaatcgtca
     7441 cctagacaac aacagcaatc atcacagcaa cagcaacaac atccatctaa atcattacgt
     7501 cttcttctat tataattgtc agccctattg ctataatcat ttctatattg tgtataactt
     7561 ctaagtgcat cactatattc actattttca ggctccataa attttgctct ttttaagaag
     7621 tcttcacctt cttcataata tcctatgttc attgcagaaa aaccagttaa ataataccac
     7681 tctgcacatt tgtcagtcaa agtttttaaa aaatcatatg cttttttaaa ttcactattt
     7741 tctatgaatg atcttgctct cataaaattt tcattattat aagtattact gtacattctt
     7801 tccacctcta ctttctaata tattaatata tcttaaataa acaccagaat aaattatatt
     7861 ttctattatt ccaacatttt tatttagatt tagattatca attcccctag ctaaaaatcc
     7921 taatgatgtt actattattt tttttacttt ttcttttaac tcatcatttt tatcaatata
     7981 ctctataaat ggattatatc ttcctttctt aaaatcttca tctaaatctt cataggcatc
     8041 tagtagatat atatacttac ctatattaaa acctatcatt cttaagtttc tctcattttc
     8101 atctttttta tagacaaata cttcacccat tatatttcca aatatactag atacttcatc
     8161 tatatttata tttttatctt tttctaactt atttaattca tttagttgtt gttttatata
     8221 ctctgctttt tcaggatact tttcatatgc taattttaat ttgtttttat atatataata
     8281 tgccaattta tcttttatgc gtttatcatc cattaaatta tcttccaatt tataatacgt
     8341 taaaagaata ttcatacttg ctgcatattc tgtaatatca tttgtaatta cctttttctt
     8401 tttaaatgga tttactatac acacttcctc tgtacttata gactctgggt tatatactgc
     8461 tgttaataaa acaattaaaa atgttatatc atagttcaaa gaaaacctag agatttctcc
     8521 atgatttctt tttaagtatt tacatagtcc acaatagtaa gctttgtaat aatcatattc
     8581 tctaaatgtt aaatccattt tgtttatttt aacatatcca aacataaata ctcctttttg
     8641 tactattttt tatttagatt atatatagta taacactttt tatcaagatt atataattta
     8701 cagtattcta agaaacttaa aaaattcctt ctaatcattg tatcttaaat ttaaaataat
     8761 tagaaggttg ggttaaaaat aatattaaat tatatactta tattaactca tacaagttgg
     8821 ttatgcttat atcaatttaa gttttaaata attggtatat atttaaaact acctacagta
     8881 tccttcaatt ctttttttgc tttatttatc accaattcat caagcattac atcatttatt
     8941 gaacatgata tagatttaga tgccaataac attgccttaa atcccatatc agaacctgca
     9001 ctggcacaag attgccatgt atgggcagaa ataccaatag gccaaactga acaagaacat
     9061 tgtgctgtag gaattatgta gctaacatct ccaatatcca atgataatga tatacagtta
     9121 ttatgagtaa atgtatcatc tgtaacctca tcatgtaaat tcatcttagt aatatcctta
     9181 tttccactta atacactaga aacactactt cttttatcta tagacactgt ctcagctaat
     9241 ttatctgcaa aatagtagtc atcttcatta tagttttgta cacctactaa tttcatattt
     9301 tgtgatagaa tatctgttaa tattgtattt ggaatatagt catatactcc acttataatg
     9361 tcatattcca taatggtacc agtcattaat gctgctcctt ttgctatatc aacaatccta
     9421 ccaaatacat ctcttacatg ctccatttta actcctctta tgtaatacca cacttctgca
     9481 aaatcaggaa ctatatttgg catttttcca ccattagtag ttacatagtg tactctacaa
     9541 ttatcaaata tatgttctct caaataatta caacctatat tcataagttc tactgcatca
     9601 agtgcacttc ttccgttata aggagcttgt gctgcatgag cactaatccc attatatcta
     9661 aatttcacag agtaattagc aagtgttggg attcttatag gagtatttat atcaaatgga
     9721 tgccaactaa aagcacaatc aattccatca aaaaaacctt tttttatcat caatactttt
     9781 ccagataaat cttcctctgc tggacatcca tagtatttta tagtcccttt cagctttttt
     9841 agtttgatta attcctttac tgcaattaca gctcctattg aacctgtacc aagtaagtta
     9901 tgtccacatc catgacctgc accaccatct acaataggtt ctttagtagt ggatactttt
     9961 tgagacaaac catctaaagc atcatattct cccaaaactg ctataactgg tctaccttct
    10021 ccataactag ccacaaatgc tgtatccata ccttctaatc cctctatact aaaaccatgt
    10081 ttttttaaac attctttttg taaatttgaa gcatagtatt ctttatactg aagctctgga
    10141 tttttccata tcttatctga tatatctctt aattctccct gtatctcatc tatatattcc
    10201 atcaaaaact ttttatttaa attctccata ttaattatat aaacctccct gtttctaata
    10261 acttatcgat tatcagccaa aatgactaat tttaactgat ttaaaaatat tttctaccat
    10321 acaaccattt tatacaataa aacctcttga cttgtaagtt tcattttatc aagtaagagg
    10381 ttttcaagtt ttataaaatt tttagcatgt taaccaatca agcatattaa cccataattt
    10441 attatagtat ttccaatcag taaattcttt tggaccccag tgaggtgcac agtcagaact
    10501 aaagatagca gattttcctt ttccaaactc gccaacagct acaaatgggt ctcctccaat
    10561 agttgctaaa acaggacaat tatctctagc tactgttttg ttatatccta aaaactttgg
    10621 ccattctgtt ggtatacctt ttaatactgg atgttcagag tcaataactt ctggaattat
    10681 tcctgctggt ttttcaactc tatcatcttt atctatcatt gttattggta atacatcttt
    10741 gatagcagtt tctccgaatc tagcttttgc atctattcct gtaaatgaca tatatccacc
    10801 taccatgatt aacgccccac cattatttac atactctttg attagttcaa gtctatctgg
    10861 attactattg caatctataa aagtactatt agataataag aacgtattag aacctatatc
    10921 agataatatt atacagtcat actcatttaa ctcttctaat ttatacggaa aactatctgc
    10981 tgctacatgt gcaggcatat gaactgtctc atatcctcca gattctattg cttctttcaa
    11041 ccactttaca gcttcttcat aatgagttgt aacaaacgta tcaaatcctt ttatatgagt
    11101 tatatttttt acccaagatt cccctactat taatactttt ttcatttata tattcctcct
    11161 acttttataa gtttaatatt agacttgcat acataagtat actatctaaa tactccttaa
    11221 tttcaacata ttcatcaatt gaatgacatt gttctattga acctggccct aatataagtg
    11281 ttggtatttc agctaaattt ttcattactc tcgcatcatt gccagctgtt gaacctttta
    11341 tctctaattt ttttcctaga gtttcttcta gtattttatg tgcattcact acaaaatcag
    11401 aatccttgtc catctcaaaa cctaaccctg attgatatat gtttatattt ggtttattat
    11461 ctttaagcca taaatctcca ttagcccttg tcattatgac atttgttaca tcatttacaa
    11521 cttgttcata actcattata tttggcaaga agtgtacaca taaattaaat acacacttat
    11581 ctggcacagt agaacctgct gttccaccat ttattacacc taaatttatt gtaggtgaag
    11641 gtaatagtgg atgtttatat atcataagcc agttatgttc caaccctttt atatcttgaa
    11701 gcaacaacat agccttctca attgcattta caccctccca cttactacca cagtgaagag
    11761 acacaccttt aacctcaact tcaaagaata caaatcccat atgtgcaact attaagtttt
    11821 gttctgatgg ttcacaaatt atgcaacaat ctccaccaat accattcata actgcattta
    11881 tggtaccatt tccgccacct tcttcatcta ctactgacat tatttttaca ttaccaggta
    11941 catttagacc actatctttt ataagcttta cagctaatat tgatgctata agtccagatt
    12001 tcatatcagc agttccaagt ccataaagtt ttccattatc ttctgtagca cgatatggat
    12061 tatatttcca cttacttata tcacccggtg gcatagtgtc tacatgacca ttaaatacaa
    12121 ttgtcttacc aggtaaatca tcactatact tacaaattaa attatatcta tcttgataat
    12181 tgtgacctag atttccttct ttatatatat tttttgcttt tttaattaat tcttcgctta
    12241 tttcttgtct atctacacta aaacctatgt aatttgcaag tttttcaata tattcctgtc
    12301 cttctttttc aaatccacct agtattccat gaccaacatc ttcagtcttt atacttacaa
    12361 gttcttttaa ataatctatg tattcttgtt ttttactatt taatgtatct aagagaattt
    12421 ttttcatatt tcctcctaag atttattttt acatttaaaa tttcaagtct aatctcatct
    12481 atttaagcca tagtaaactt tttcacttag catattccca ttcaatgtat aaagatgtat
    12541 gcaaattaaa gtataaaaat atatacaaaa actcaataat ttttatagtt tataagctaa
    12601 aatttaatta ctatttagat ttagctgatt tttttaattt tatattattt atccatatag
    12661 caaataacat taccaaacct tttataatca tttgattata tgaagataca cttaataagt
    12721 ttaatccatt tcctaatatt cctattattc cgacacctat acatgtacct actatagaac
    12781 cagaaccacc catcatatta gtaccaccaa gcacaacggc tgctatagca tccaattctg
    12841 ctccatctcc aacagttggt gaacctgatg ccaaacgtga tgatagtatt atcccagcta
    12901 atgctgttag tagtccagct agtgcgtata cttttactat aactttattt acttttactc
    12961 cacataatct agcggcctct tcatttccac ctactgcatg tacatgacgt ccaaaattag
    13021 ttctttttaa tagaaaatgt cctgctatta caactataat cataattata actggtattg
    13081 gtattggtcc aatatatcct ctaccgagca tcttaaatgc atctgtattt actgatatag
    13141 gtcttcctcc tgtaaataca aagcttgccc cacttattat cgttaacatg gctaaagtta
    13201 caatgaatgg aggtagtttt tgtgttgaaa taattgcacc ttttatgact cctaatattg
    13261 tccctattgc taatgcaagt atcatacctc cccatatagg tgcattataa ttcactactg
    13321 ttgtagccca aaatgtacct actaaagcaa ttactgctcc tacacttaaa tctattcctc
    13381 ctgtaattat tacaaatgtc atacctactg caagtattgc atttattgat atttgtcttc
    13441 caacattaat taaattgtct aaagttaaaa agttagatga agctacactc attattataa
    13501 aaattattac aagtcctaca gctgcactcc cttggtctct aaatacactt gttaattttg
    13561 tcaataatgg agaagatttt tcttctttat gcttagttat tgaactcatt aattttacct
    13621 ccgaaagcca attttaatac attattttca accatttctt caccttctaa aaatccactt
    13681 atatgacctt ctctcataac cattattctg tcactcattg atattaattc tggtatttca
    13741 gaagatatca ttattatact tacaccactc tccactaaat ctcccattag attgtatatc
    13801 tctgccttag catttacatc tatacctctg gttggttcat ccataatcaa tatatctggt
    13861 tgtaataaaa gccatcttgc tattatagct ttttgttggt ttccaccact taaactttgt
    13921 ataacttgat tcatatgtgg tgtttttatc tttaaagctt ctatgtattt ttctaaaatc
    13981 tctttttcct tttttctatc tataattgat ttaaacttag atatcttttt taacccagcc
    14041 atagttgtat tttctttgac actcatttgt aaaaacaatc cagtaccttt tctatcttct
    14101 gttattaatc ctagtccatt ttctattgca tctgatggag ttttaaactt tacttcttca
    14161 ttgtttaaat atatttttcc agaatcatat gttctaagtc caaatatagc ttctactatt
    14221 tcacttctct tacttccaac tagtccacct attcccaata tttcaccttt tcttatatta
    14281 aagctaatat cattaaaaac attgttctta gttagatttt ccactcgcat aatttcttct
    14341 tttatttcta cttttctttt tgggaaaaat tggtctagct ttctatctat cattaaatta
    14401 actaattctt cctcagacga tacatctttg gtatttaaag tcgaaatcgt tttcccatct
    14461 cgcattatag ttattctgtc acaaatctca aagagttctt ccatcctatg ggatatatat
    14521 attatactaa ctccactctc ttttaaatca tttataagtc taaaaagtat ttcagtctct
    14581 tttttactta ttgaagaagt aggttcatcc attattaata ctttagtttc tgatgataaa
    14641 actcttgcta tttctaccat ttgtttttga gctatactaa gctctttgac taaactattt
    14701 ggatttatat ctattcccat attatcgaaa atctttttag cctcttcatt catttttttg
    14761 tcattggtta agactttgcc atttatttct tttcccataa aaatattttg tgctactgtt
    14821 aattcgtcaa aaactgttag ttcttgatat atggcattta tacctatctt tttagagata
    14881 tctggggata tattctctat ttctttgcct tcaaaaataa attttccaga agttttcgaa
    14941 tgtgcaccag ttaaaatctt tatcattgtt gatttaccag caccattttc acccagtagt
    15001 gcatgaactt cgccatgaaa taactcaaaa ttaacattat ctaatgctct gacaccagga
    15061 aattctttag caatattact taacttcaga attatattac tcataatgac actccttttt
    15121 aaataggatt tctttcaaat aatctcattt tattttacta attcttaaag tcttttatat
    15181 tttccttatc ataaagtaaa gctggtactg gtatattctt ttctaccttt tcccctttta
    15241 tagcttttac tactgcttct acagctaaac gtcccatctc tttaggttgt tgttgaatca
    15301 tagcaagaat agttccatct gttattccac ttgatgcttc ttcagttaag tcaaatccta
    15361 caatcttaac atccttattt tttgcagatt caagtgcagc tttagctcct agtacactat
    15421 tttcagctgt tgcatatatt atatctacat ctggattaga ttgaattaag ttttctactg
    15481 tattaagaga ttcttctctg tcatatcctg gttgtgaatt taatatctta acatttgctg
    15541 aaccttttaa tgcatcttta aatccatcta ttctctgcat ttgtatttga gattttaaat
    15601 ctgtcactat tgctatttct gactttccac ctaacttttc atctatgtat tttttagtgt
    15661 attcccctaa ttttttacca gcatcataac taactgttcc tacataactt gtaatatttt
    15721 cagtatttaa tacagcatct actgtaacta ctggcatttt ttcaaatgct ccttctactg
    15781 ctggtactat agccgaatta tcagttccaa gtactatcat tccatctaca ttttgttgta
    15841 taaaatcttc tattgctgat gtttgcttag ctacatcttg gtctgggtca tttactataa
    15901 ctttcacacc taattcttta gctttttctt ttattccctc atcaatatct ataaaaaatt
    15961 gatgttgaag agttattgta gatactccaa tagttaaatc tttcttgtct gaaccacctt
    16021 tattatctga tttacttggt ccttccattg aacaccctgt taacattcct attgctagta
    16081 ttccagcaat tcctaaagat aaaatttttc tcactctcat aattaacctc catttttaat
    16141 agttttaaat ttgaacaaat tagattttta tttattattt aaatactttt caacatcttc
    16201 tttatagggc ataccagatt gtgcacctag tttagttaca gaaagacctg atactactac
    16261 tgcatattct actgctgtat ataaattttt cccttctgtt atagccactg ccaatgctcc
    16321 attaaatgta tctcctgctc ctgtggtatc ttgaacatca acacttatac aagatacatg
    16381 cttgatttcc tcaccatcat aaaatctagc tccatttttt ccttctgtta ttacaagttt
    16441 atttggatat ttttttaata cttcttctat cccttcattt gtgtcaaaaa ctatcttata
    16501 ttcatgttca tttggtgtta agtaagttac tttttctatt atatcttcat ttagttttac
    16561 tgctggtgct ggatttaata aaaccctaat cctattttca aaacagaaat tcactacata
    16621 atttattgtt tttaatggaa tctctaattg tagcaatact atatctgcat tctttatctc
    16681 ttcttcattc tttttaatta attctatatc tactagctca ttagtccctg gtacaacaac
    16741 aatactatta tcattttcac ataatgttat aacagcaaca ccagaacttt tgtgattatt
    16801 tctggatact aagctataat caactttatt cgttctaaaa tttcttatta actcctctcc
    16861 taagccatct tcccctatgc atgatatcat ttttacattt gctcctagtt tagaagctga
    16921 gatagcttga ttagcccctt ttcctccagg tgatgtaaaa aaactattac ctaatactgt
    16981 ttctcctttt tctggtcttt tatctacaga acataccatg tccatgttta cacttcctat
    17041 gacaactatg tttcccatta cattactcct ttacatatct atttatgtct ctcgtgctgt
    17101 tattcacttt cttttgttga atctcttatg accaattctg gtttgaaaat caattcatca
    17161 aacgattctt ttttatctcc tcttaaacaa tttatcaata tttcactggc tttatatcct
    17221 atatcataag acggctgttt tactgtggta agagaagggc ttattagact tgatgtttga
    17281 atatcatcaa atcccacgac acttatatca tttggtatac ttaatcctct ttctttaaga
    17341 cctcttatga cacctattgc aatcaaatca tttgcacaaa atattgcatc aaaatctatc
    17401 ttttctaaat tttttataaa ttcttgtccc cattcaatct tatattttcc ttcaaataca
    17461 taagcaggat tgtagcttaa attgcactcg attagagcct ttttatatcc ttctaatcta
    17521 tctactgcta tttcattttg aagtggacca cttaggtata ttattttctt atttccaata
    17581 tctaataaat gttttgtagc tatataggcc ccttcaaagt tatttatttt aacaattcct
    17641 tttaaggttt ctttgttcat acttatcttc ttatcaatca agacagttgg tatttttata
    17701 tctttataat ttgcttcttt ccagtttgta tttgaagatg ctgcaaatat aattccatct
    17761 atcatcctct ctgatagtgt tcttattcct tcatattctt ttttagcatc ttcatctgta
    17821 ttacataaaa ttatattgta gccttcttca ttagctttat cttctacacc tcttgataca
    17881 tctgtaaaga atggatttcg tatatctggt ataagaagcc ctatagtatt agttttttta
    17941 gttactaaac tttgtgctaa tttatttggt acataatttt tttccttcat tattttcaaa
    18001 attttttctc ttgttgcctg acttatattt tcatctttat tattaatgac ttttgacaca
    18061 gttgttttag aaacaccagc caattcgcca atttctttta tagttatact caagaagttc
    18121 acccccaaaa tttaggaaac cgttttactt aaccggttac ctagatacta tcacatcttt
    18181 ttttcatttg caaccatttt atataaattt tgatattttt cccttttttc aaaatattgc
    18241 aacttataat tcaattttaa tatttaaatt aatctgcaaa aaaaaattaa tatactttta
    18301 taattatcta aaagtatatt aattaattta agcagtattt attaaaattc aaatccttgc
    18361 tctataatca tttttttatc attttcaatc ccacttccaa cagttgtcaa ataatcacca
    18421 acaattgcag aatttactcc cccattaaat ccaactttgt catatccctt taatgatagc
    18481 cttccaccag cataccttat gtacacatta ggaattataa acctaaatac tgctgttgtt
    18541 tttagtattt ccattggttc taatacatca taattttcca ttggtgtatt cttaatagga
    18601 tttaaaatgt ttattggaaa tgattttaca tttaattctc gtatttcaaa agccattttt
    18661 agtctctgtt cttcactctc attcattcca attataccgc ctacacatac atctagccca
    18721 gcttttttag catcttttat agtttttatc ctatctttat atgtgtgtgt tgtacatata
    18781 ttatgaaaat tatctctaca cgtctcaaca ttgtggtgat atgtagtcac acctgctgac
    18841 ttcaacattt tagcttgctc ataatctata atacctaaag atgcacataa ttttaaatta
    18901 gtattttccc tcaatccttc atagatattt aaaatattat taaactcctt tcctgacata
    18961 cctttaccac ttgtaaccaa tgagaatcta tgcactcctt tactctccat ctctttagct
    19021 ctatttaaga tttcattgta atctaataat gaatattctt ctacaccagt tttataataa
    19081 gaagactgag cacaaaattt acagtcttca ctacatttgc cagatttagc attcattatc
    19141 gtacataaat ctgcttttct tcccataaaa tattctctta tttcatttgc agattttaat
    19201 agaatatcaa aatcgttttt attatttgta tcaaggctta ttaaattaag agcttcttca
    19261 taacttattt ctttttctct caatacttta ttttttaatt ttattatgta tttttccata
    19321 tatcctccta tttgtcaact taatattttt atgtagttta cttattatat atagtattgc
    19381 atatataaca tttattggtc aactttattt tagacacaag tttactatac acaaaaaaat
    19441 actgcttcaa aacaatatta gtatatagat tatacatatt attattaaag cagtattttt
    19501 tattagaata taattcttac tggtttataa aactatcctt gtcttaactc catccaagct
    19561 ttccattgta ataacttcta agccttcata ttctctaaat agccatttta aatccttcat
    19621 ggcttgatta acctgacttt ttgttagatt atttataaaa tattcttttc tagtttcctc
    19681 atactctttg ctagtcaaaa agtttcttag aaaattaaac gcaaatacac ttggaatatt
    19741 gtttacatta gccttcttgc tgttttcctt ctcatagtaa attttcataa atgcatactc
    19801 ctttgatact tttagatttc tcttacaata attatatgca tttaagtgct actattctta
    19861 taattttatt aattcatatt ctttacttcc catacccatt tcacatgcat agtctattat
    19921 tctagttcca tttacatgag gatgttcatg tttgaaaaca tcatgaccca tttccttaca
    19981 aatcaaatca tagcatgctt gttcaatagc tacagggtct gttgatgcta atattcctat
    20041 atcatgggca attggtctac ctgaccaagg tacacaatca caaagtggag ttacattcat
    20101 aacaaaagtt atatacccta ccttgtcttt tttatttgat actgctccat aagcgtattc
    20161 tgccatcttt tcgacaaaca catctgagtc actttcccat tgtatagtta ctgctctagt
    20221 tggacagaca gttggacatt ctccacatcc ataacataca tcagaatcta taactgcttt
    20281 tttatccact atacttatag cttttgtagg acaagaatta acacactttc cacaacctac
    20341 acacttcttt tcctttacta ctggagtaac atcagaatgt tgcatttgtt ttcctgctgc
    20401 acttgcacat cccatagcta agttttttaa tgctcctcca aaacctgctg cttcatgacc
    20461 tttaaaatga ctcattacta tcattgcaga agaattataa atttctccac ctatttttac
    20521 actttcaaaa tgttttttgt ctatttttac attctcataa tttctactat ataatccatc
    20581 tgcaattatt actggtgcat ttacaactgc ataagcaaat ccattttcta tagcagttgt
    20641 aagatggtct acagaatttg ttctactccc tgtatacagt gtatttgtat ctgttaaaaa
    20701 tggctttcct tcgcagtctt taaccttatc aaccacttgt ctaactgcca caggactcat
    20761 atatgtagta tttccctttt ctccaaagtg aagtttaatt gcgacttggt catttttttc
    20821 tattaaatct ttgaatcctg cttcatcaaa taatcttctt acattgtttg gtacgttttt
    20881 attttgcgaa tttgagtata aatcacaaaa atatactttt gacttttcca tatctacacc
    20941 cctttaaaat atttacttat actaatttta tcacttttaa agtaattttt agtatatttt
    21001 aacataatta aatattctta tatttatttg atacaaataa tattatttgt attattttct
    21061 acacttaatt ctatatatta aactacacct aaaaatcaaa aagacttgaa acttaagtcc
    21121 aagtcttttt gatttttagg tgtagttttt aacaacataa gattacttta ccttgtgata
    21181 aaggtattat taaactggtt ttttattaaa taaaataaca gctgctagta aacatactat
    21241 agaaataaga actgttataa taattggaat aataaattct ggcattgcca ctttccctga
    21301 aatcaagtct atattttttg acatcaagaa attaggagta taaggtgcaa tctgtttagg
    21361 aatagaaatt aaactcaata agagagttgc taccaataca agtaaaacac tggcaaatgc
    21421 tggtctaaat agtacacacc caagaattaa tacactaata tacataattc ctataagcca
    21481 taaattaaat gctgaaaata taatatgatt aagatttgca gttggccaaa aatacattgt
    21541 atagccataa gcaaataaaa aactcaacca aaaaccaatt gtcataataa tcaccgtaac
    21601 agagaattta gacaatacta tagatgaacg tgataaacct ttagtcagca taataacaag
    21661 tgtcccttta gaatattcat ttgataaaat attacaaaaa ataattagag ttaaactcat
    21721 accaagacca gagatattgc taaaaaattg tgtccaagaa tctaaagcag ttggtgcagc
    21781 agtaactttt aaagtcggtg caaaatgagc aatcaagtct ggcataaatt ttgcagaaat
    21841 aggactactt ataccaaata ttagaaataa aataattaaa ctaaataatt tataatttct
    21901 taaattctct ttaaattctt tttttgtaaa tgctatgtat tctctcactt tactacctcc
    21961 aaaaataaat tttcaagtga taattctatt agttccatct ttactggaca aagattcatt
    22021 tctgcgagtg tagatataac tgttttttgt attgctttta tatctttacc atgcaaaaca
    22081 atttccatat tagtttcttc tgaatctttt agtaaggatt taataccatc actagactta
    22141 aacttttgaa tttcatcatt acttgcaaac tccagtaaaa gtctatcctt tccgtgcata
    22201 ctttttattt ctgaaagtgt accactaagg gcaatgcttc ctttgtttaa tatagcaaca
    22261 tggtcacaga ttctttcaac atctgatagt atatgtgttg aaaatattac agttgttgag
    22321 tctttgattt taagcataat atctaatatt tcttttcgac caacagggtc aagtgcactt
    22381 gttggttcat cacaaataag taatttgggg cgtgaaagca aagcttgagc tataccaagt
    22441 cgttgcttca ttccacgaga aaacccacct attcgtctct tttcatttcc aagacccaca
    22501 agtgataaca actcttcact ccttatctgt atttcttttt ttgaaagtcc cgtaatttca
    22561 ccacaaagag aaagatattc aagtggtctc atatagttgt aaaactctgg aacatcaggc
    22621 agataaccta catgacgatt agaacttgtt ttcccatagg tcactttctc accacaaaca
    22681 tctatagttc caccatctgg tttaagtaac ccaagtacca ttttcattgt tgtagtctta
    22741 cctgcaccat tcttacctac aaacccaaag actgaccctt ctggtacagt aaaatttaaa
    22801 ttatctatta tctttcgatt accaaaacct tttgataatc catttattga aacaatattc
    22861 atcattcttc acctcttcct attgtaaaat acaaaattgg tcctattaga ctaataaaca
    22921 gtactacaat aatccatatt gccttatttc caattttata atttggatgt ctcaatacat
    22981 gaacaagtgc agtaattata agtattaaat ctaaaataat aacaggaacc aaaagtggta
    23041 agtattccat caaattttcc atactcttat tcctccaata aagataattt ttctataaga
    23101 aatttgtatt ctttgttttc acttaataca gaaaacattg gattattttt aatagcagca
    23161 acaatacctg cttttacgat tgtatcatca cgtgtaatac ctgttccaat ttcagaaatc
    23221 catctgtcaa gtttattaaa aaagtcatcc ccatgtatta taattgggta tatatcacgt
    23281 gttgctaaat ctacatattt tcgtaatgat ttaatagctc cttcattatc accatgtatt
    23341 aaattaattt gtgcctgtgt taaatatgaa gaaagcataa tagcaggaga taatgtatca
    23401 agctcaaata tatctgaaat tgctagaata cgtctttcta tttccttcat ttgtaattta
    23461 tctgcatttt gcaaaatacc cactagattt tggactaatg atataaggtt ctgatatgca
    23521 ccaagttgaa atgtttctct tgcttcatcc atttgaccat tcatcatttg cccttgtgca
    23581 agaagtatag attcatttat catgggaaaa ttgctgtttt gcaataaatc aatcacttgt
    23641 atgggttgat ttaacaatat ataacaagtt gcctccatac tttttgcttg acggcaaata
    23701 tctatgtcat tacaagtttc ctgtatacga ataaatattt ctaatgcttc actaattaat
    23761 agttcacgct ttttttcatc tacaatatca tagtgattaa ctattaaaag acccatccga
    23821 aaaatcaaag gaaaacatga ataatatttt tttatgattt ctcttatttc atccatgact
    23881 tcatcaaatg gtttaaccgt aaagtctttg cacagtttat tatacagttt attaatatct
    23941 tccttcatca tttgaggttc ataacatatt aactcatcaa cggtaatgtt gaaatatgtc
    24001 gcgagttgcg gtaaaaaggt tatgtcagga tagctttgtc cagtttccca tttagataca
    24061 gaagctttag aaacgcctat ataatttgca agttcatctt gtgtaattcc tttttcttta
    24121 cgctttaaaa tcagcgtttt tgcgatgttt aattcattca tgtcaatccc tccttatgta
    24181 taattatatc cttaaacatg taaagctaac aagcgatttg aagttgactt ttgacgaaaa
    24241 aatcaaccac agagaaacaa ataaacaagt atataaaata tatatttaaa tttatcttta
    24301 atctcctttg taaaatatgt aaactttgta aataaaatcc atattatata aaactaatag
    24361 ttaatctatc taaatacagt ttttatttat cacgttttta aatattttgt gtaaaacctc
    24421 ttttaatata aacaccttat tttcatttct catttcatat tctttttaaa atactgaata
    24481 taactcttcg attttccatt taatcctttt ataaagttat tattcgtatt tattcctcta
    24541 attataacag gcaactatca tgtattggta tttgtctatt atataaaaat ctataaaaga
    24601 aaagcagtca atcatttaga ttaactgctt gtacatatat cttattaaac tgtataaact
    24661 ataattttta ttattctcca ttttcatccc aagtcataaa tccccatcca ctatctggat
    24721 aagtatcaat agacttttct ctaatcatat aaccaacttt ataacactct tttgttattt
    24781 tattagatag tatacatcct tctccattta tctaattcca tttaattaac ttttcttttc
    24841 aaccttaact tttataaaat catctttttt aataatttca tacttatttt ctcttcaaca
    24901 tcatcaaatg agggtgtctc aaaattaact ttttacttca taaggcactc ttttttgtat
    24961 gaagtaaaat atattttcat catttcaaca ataagtaaga ggcttatctc tattttgaga
    25021 cagccccatt tgatggtgtt gaacatttaa ataaggttga actcgtttta tctctctttt
    25081 taagatatcc gtaaatttgc acataaagtc tcttcttctt ttacaattct aatagtttta
    25141 ttaaagccaa agtatatatc tccatattct ttcgtatatg atttattggt actctttcat
    25201 ctactccatg accaccagtt ttatacgcta agaacttagg tccaaacgcc accatatctt
    25261 taaaccaact tgcatatgtg ccaccaccca tagcaattgt atatccattt tcatctgtta
    25321 cttcttcata ggcttctaat aattttttaa gtactaaatt actctcatcc acataatgta
    25381 agtctttatg agcaataacc tctattttcc aaccattaca aaaaaccttt ttgaatctat
    25441 ctattatatt gtttaaaact atatttttac cataccttat atctaactca catacgattt
    25501 tttcctcatt tacttttaat attcctaaat ttaaggtagt gtttttgaat acctcatcat
    25561 attgattaat ccccaatgca tctccataat aatcactaca aaggtatttt gaaactaatt
    25621 ctatatcttc tctatgctga aaatccatat tatcctcaac tatctttatt accattttag
    25681 atatagcatt ttctcccttt tcaggattac ttgcatgtac agctactcct ttagtagtta
    25741 actctgaaat aattccatta ataatttttg cagtacaatg agatggaaca acattttctt
    25801 tagttcctcc acttactatt atgtaaggtt tacttttgtc aattttaatt tctttttcta
    25861 tccttatatg aacccttcct ttttctccat taaccactgg atacatagca tctggagtaa
    25921 atcccatact tggaatttct tcacctttat ctaagtaata tttgatacat ttcatacctg
    25981 tctcctcatt tgtaccaaaa attaatctta ttcttttatt aattgtagga tacatatcct
    26041 ctatgttttt caatacatgt ataagcatag atacagcacc cttattatct atgacacctc
    26101 ttccataaat aatattgtca attactgctc ccgaaaatgg gtctacactc cacccctctc
    26161 ctggtggaac tatatctaaa tgcattggaa tccctattaa ttcctctccc tctccaattt
    26221 ctgcatatcc aatataatta tcaatatttt taacactaaa acctaaacta gcacagtaat
    26281 ctaaagtttt atctaaagat tttttaggtc ctataccaaa aggacattgt gaaataggtt
    26341 caccttgttg tgaatcaatt tttatcaatt cttttagaaa ttctatggtt ctatttaaac
    26401 tattatctac acttctgctt atatccataa atcaacctac tttctatctt tttaaagcct
    26461 gtccttaaag aacaggcttt taacattaaa aattattttt ttgtaaatac taattcacaa
    26521 acttcatcat catgagcaca tttttgagca aaatctaatt taacaccttg tgcgcagtca
    26581 actcttccat aatccccata acaagctaat ctacaaattt cttttctttc ttctttagtt
    26641 aatccatatt ctttccaagc agcatctaat ggacagtgat ggaattttaa aacgccattc
    26701 tcatctgtat tttctactaa ttccatttca aacacttttt gtcctttact gttatataac
    26761 atttctgcca tttttcctgg agtatctgct acgttatatt tttgacctct cattttacca
    26821 aatccatata ttgcttcttt acatatatca tctggattag ctcctaattt ttcagcttct
    26881 ttcataagaa gatagaacca tactgctctt tctcctgttg ctcctctaat tccttctaaa
    26941 tattcctttt ctgtatacat tttttctgac atttctttct cctcctaaaa ttaaattcta
    27001 tattttaatc actgtgaatt agaatattcc aatgaatgac cctaccaatg ctaatacaac
    27061 taaaattact aataacttag ttattgtcca cttcttgtat ttcattcccc aatatacgaa
    27121 gaatacaaca ccaagtggta ataaacctgg agcaatcata tttaatgtat cttgaacaac
    27181 aattgcttta ccaccaatat caaatgatag cggagttgaa agcttaactg tagttgcaga
    27241 taatgctccc atcataaaca ttcctagaat tgaagcacca tcaattatct tattgacaat
    27301 accacctgat agaattttct taattgaatc tctacctaaa gaatatccta aatgaaataa
    27361 gtaataacct tcgcaaaata gtaatatact aaacattatt gggaaaaatg cacctataac
    27421 acttccttct gctccaaatg aagcacctaa agctaagaat attgtttgaa atgtaccaaa
    27481 atctaaagta tctccaattc cagccaaagg tcccataaga ccattcttaa cacctgaaat
    27541 aacttctcct gggatttttc cttcagtagc tttctcttct tccatagcta aaactgtacc
    27601 gtgaattaat cctccccata tagcttgagt attaaaaaat tgtaagtgtc tctttaacgc
    27661 atctactaaa tcttcttttc tcttatataa cttttctaaa gccggagtga aacttgcaca
    27721 aactgctaat gcttgcattc tttcaaaaga gttggataat tctgctgtcc accaccatct
    27781 tagatatgtt tttgttacat ctttctttgt aagtactctt gtcttattaa cttcagttgg
    27841 accttgtcca tttttaactt ctttattttt tatttcttgc attatacttc acctaccctt
    27901 ttgtcttctt tcataaaggt aattaaaaga gctatacaaa caccaaatat tgcagctgca
    27961 gtaattgata tttcaaaata ttgaaccata aaaaatccta taataaacat tggtaagaat
    28021 ttatttttac ctatagtaaa tattgttgtt gcaaaaccta atgcaggtaa tataccgccc
    28081 attactgtta atccattcat taaccattgt ggtataacat ctaataatga ttgaactaaa
    28141 tctgctccaa aaaagttaca tacaaaaact attggaaacc ttaaaacaaa cccaaatatt
    28201 aaagaataaa gtgttgcaca tctccagatg ccttttgtat taccttcttc agcatactta
    28261 tctgccttat gaaccaatac agcattacca gttcttctta agttattaac taatactcct
    28321 ataacaccta aaggtaccgc aatagatact gcaacttctg cattaacacc agtttgaagt
    28381 gctactggta ttgcaataag agcagctaga catttatctg atggaatatt tccccctgct
    28441 gcgaccattc ctagataaac catttctata cttgcaccaa caatcatacc agttgttaca
    28501 tcaccccaaa gtaatccaag gctaaaacct ataaataaag gagactttag tgttgagaaa
    28561 agggtatacc ctgcaagacc tgctgcaaac caataccata atcctgttac aattgccaac
    28621 atcaaaacag attccattta taattcctcc taatttatat tttttattta aatttcttta
    28681 acgcattttc atatgtcata gatgattcct ctggtataac ttgtaggact atttcaaccc
    28741 cattttcatt aagttcatta agttgttcta catcctcatt tcctaatgaa acagctgtaa
    28801 acaccatttt ctttcctgct tcatttggaa tacctcctaa ttgaatcttt tcatatttaa
    28861 gtccagcttt ataagcctta tttgccatat caacattttt aaatagaata aatatatttt
    28921 tatctcctaa agtgttgttt tggaatgctt gtcccgcatc ttctgctgtt aaaataacta
    28981 cttctactcc tgatggtgct gccattttat atatgtcagc cataaattca tcttgaccta
    29041 agaagtcatc aactattatt attttttgag cttgagcgat ttttacccat tttgttataa
    29101 cttgcccatg aattaatctg tggtctactc ttactaatgt tatttttgcc attatattca
    29161 cctcataatt tatatttttt taaattcttt aattaaatcc acacaaaggt tattattttt
    29221 tttgacgatt ctttctggta atgtatgtaa tttatcttct ttgcttaatt cttcatctac
    29281 gattaaaatt gtctgtaagc taagtccatt tattgcatct attcctcttc ttatagcaac
    29341 agctattgcg acacttgatg tagatcctcc atataaatct gatattataa ttttcacatc
    29401 ttctttatct actacttctt caacctcttt cataaataca gaaacatctt tttcagaact
    29461 tagtgataaa acttcatatt gatttgacaa tccaaagttt ttatttgttt cttctactaa
    29521 gacttttccc caagttccat ggcacagtat gattacctta tatttattca ttgctaaata
    29581 aactctcctt tatagcgatt aatattttgg tttaattcta cttcttcttc atcaggtacc
    29641 atttgaattg atacattaat attcttttta ataaattcat ctattaaaag aaactctttt
    29701 ttattaatgt atacattttg agatattttc ttttttccta ttcctgtagg tattcttcca
    29761 acaataagtt ttttgatatt aatcccttct tctatcattc tatttgcagt atctaaattt
    29821 ttaattaata caaaaacgtt atcatcagct tgattattat aaaaatatct ccttgattca
    29881 cttacagtta atatcgataa atcaatattc tttggtgctg ccatttttat caaaccttta
    29941 gcaataacat cattggttgt ttcatcatct actactacta tcttttttac acctagatgc
    30001 ttaacccatt tatatataac ttgaccatgt attaatctat catcacatct gcaatatttt
    30061 actaaagaca tttttaatca aactcctttt tctattacat tgagctaaga actttattaa
    30121 tattgtttat accagtttgt cctgcttcaa tacatgcttc tgctaactct tctaaacttt
    30181 ttccctctct attaattaaa gcttcaagta gcattggaag atttactcca gtaagtgcat
    30241 gaaacttgcc acctttttta aggtttaaac ttgcaacatt acttggcgaa cctcctaata
    30301 ggtcagctaa tactaaaact ccgtcacctt catctaattc atttaacttt tctacaaaat
    30361 ttttatttaa gtcttcaata ttatcattcc tatttagttt aattgctgct gttctttctg
    30421 ctggtcctgc aataagttca cagcttttta taatttcttc actaaaactc ccatgagtca
    30481 taactattat tcctatcacc aatttcacct cacttttctt gtcacttttt atataagcaa
    30541 ttgccgtgcc aacttatgtg tatcaataac aaatagctat tttacaggat ttaatcaaaa
    30601 ctttttactc aatttttttt aaaaacttat tatttcgata tgtatcaaaa gattttttca
    30661 acctgtatca aatctgtatc aaaaaaagta aaaaaaagat agccttttgg ctatttttaa
    30721 attttgtatc aacttttgaa tttatctgta tcatattgtg attcaaatat atctaatata
    30781 tttgcatatt ccatatctga aataattata tcgaatgtct cttctactag cttaaaactt
    30841 tcttttataa ctaaatataa ttctttattt ctactaattc tttcttcata tgatttataa
    30901 actaaagact cttttactat tactctttca atcatacatg aacaatgaaa tataaacttt
    30961 aataaaagtt catcttgaat tactaaagaa tagtgttcac taattctatt aattacttct
    31021 tttaatataa aataagcctt ttccccattt aaaaaagtca aagttttact aatattatca
    31081 attagtaatc tatcaaaata tctaccacca ttatcttttt cagcatatgt aacttccata
    31141 tctccataat gtttctttat agattctata atattaaaat ataatttctc taatgtcatt
    31201 tctggagtta gagcctttct agttgcttct attacaatag gtgtacttac catatctatt
    31261 gcttttactt cttttcctgt agcatcacga ataactttag caaatgttaa aatagacccc
    31321 atatcagtta aaattaaaat tccctttcct ttatcaattt tattggctat ttctacagct
    31381 tgtactaaaa tatcctgaac tctatcttct aatcccatat taattgccac tgcatggtta
    31441 caatccagta aagtattggc tacattcacc atgctagatg ctgtagattc accatgcatt
    31501 atgactaata ttgctatact ctcctcattt aatcccacat acgataaata aagaaatgtt
    31561 gctaaaaaaa ttgcttcatc ttctggaaac tctactccat acattaatga catgttagat
    31621 aatatttctt ttgctatgtt atattcatat gctctttcct tcataatttc atctttatta
    31681 ggatgcttta ctatatttcc aatctttatt ctttcaatta aattctgaat atgtaaagct
    31741 atagctttta ttaatttatc taatccttct cttttgctcc atttatcatg cttttgtaaa
    31801 atatatttta cagtagttgc aattgaatca ttaacaatgt tgttataagc tgtttgatta
    31861 ctactattat atataaaagt attcattaaa ttataggaat acttctgtat gtctccatct
    31921 ataacacttc taatttgtga ctctttaata ccttcttgtt gaagtttatt ccaagtttct
    31981 tttatcattc cataaaaatc taaatcatat tttttatttt ctattaataa attttcactt
    32041 tcaaaatcct tttcttctgg taaaaaaata atatcatctt ttccaataaa actgaaattt
    32101 tgtacaaact cctcttttct attatttcca tataatgatt ctctaatatt atttggtaga
    32161 agagagagcc ttacatatac acattccctt ttataggtca tataatctaa aaaagctctt
    32221 gcacaaatta attgtatatc gctttttaat tggcctatat ttcccttaca cttatataaa
    32281 ataaatgcct taataacttc ttttgaaacc tttaacttaa caccaatcct aacactctct
    32341 tctttaaaaa aataacatat aagcttcatt ctctcttgaa agcctctttc ctctaaagac
    32401 ggaatcttta tagttacagg tattcttctt aaaaacgttt ccaacattgc tgtttctggg
    32461 tcttctgtag tggctgcaat tatcataact ctacactcgt gtaccttatt agcctctcct
    32521 aaccttctat atatcccttt atccataagc agaaatagca tttcttgtcc ctctgcagat
    32581 aatctatgaa cttcatctaa aaacaatact ccattattag cttcatgtac aataccatac
    32641 ttatctttat cagctccagt aaatgctcct tttacatatc caaaaagctg cgctaataat
    32701 aattgctgat tatcagaata atcagcacag ttaaatatga taaatggtgc attatcacta
    32761 tcttctttta tagttaaact atacttatac atatattctg caaatataga tttaccaact
    32821 cctgtaggcc ctattattaa tgtacttaac cccttaggtg gatatattac tgctgcttta
    32881 gcctgttcta tttgggacct taaacttcca tcacatccta ctaaattaaa aatattgttc
    32941 tcttttttta tactctctaa aatatactca tctttgatag aatcattttc actatattcg
    33001 tttatagagt taatattatc aaatatccct ttatttagtt tctttcctaa aatactctca
    33061 atactttctt tatataagta ctgaacaggc ttacccttta tctttataat aatactttct
    33121 tttattaatt gatttaattc cttactagca ttacttctat ttatacctac ttcagtagct
    33181 atatattctg catcaaatcc aaatctaatg ccattattaa agttcaagtg ttcttctgtt
    33241 aaccttttca agcaaattaa aactttttct ttccttgata gcttcttttg tgtcatagtt
    33301 aacctcccct ataagcagta atactgttaa acatttatta ttaagcttaa ttctacaata
    33361 ttttaatatt tttgtctaat tatgtaacta ttgattttct ttcctattcg ttttataata
    33421 taaattacgt taccctcatc ttttatagag gaggaattta tatgaatttt ttatcagatt
    33481 tacacaccca ctctatagtc agtggtcatg gctatagcac tttactagaa aatattaatt
    33541 attgtaaaga aaatggaatt aagatactag gtacatctga acatggtcct aagatgcctg
    33601 gttctcccca cagatggtac tttcacaaca ttcaaaatat cccaagaatc ataaataaca
    33661 ttataatttt aagaggctgt gaagcaaata tactagatat taaaggaaac atagacctag
    33721 agccttttgt aattcctcgg ttagattatc ttatcttgtc atttcacgaa gctgtttttt
    33781 ctccaaatac attagagaat aatactaaag ctttaataaa tgcaataaat aagcataata
    33841 atattgaaat attaggacac cttggaaacc caaactaccc aatcgactat gaattaatca
    33901 ttaaattagc tatagaaaag aatatcttaa tagaaataaa taattgttct attaaaggcg
    33961 tgtcaagaaa tggtagctcg gataactgta agtatattgc tacactttgc aaaaaatatg
    34021 gtgctaaaat catactaact tcagatgctc acatttgttt tgacataggt aactatgagt
    34081 attctgaaaa tatcttaaag gaaattaatt ttccagatga attaataatg aattatccta
    34141 aaaaacttat taatcatttt caccaaaaag ataaattact agatgttgat tatacaaata
    34201 tctaagtaat aatacatgct tactttaact cccataaaaa ttttaatact atttatatta
    34261 tatgaaataa agaaattata ataaagaagc tatttaataa agcttaatta cttttatgaa
    34321 cttgatggat tgatatggtc tatgatagca atagaaatta taacattttt aataagctta
    34381 gttttatata ccttatagta taaatctaaa aaagcatcat ctaaaaagga gctgtcgcat
    34441 gagcaaatta aatttgttct atgatagctc tttctttact tattttaatt aggtatattt
    34501 ttaattattt tatataaagc ttatgttcta agtaaaatta tgcataacaa acaaaggtat
    34561 aaaaatacca ttttttcaga taatatttaa ttataaataa taaatttaga atacttcttt
    34621 taaatgatga gagtctagaa atttttatgt gtattcttta aataaaaatt tccagactct
    34681 agcccctttt tgaatatttt aaaatttaac ttaaactaag caaattctat aatagcttat
    34741 ctctaaatat ttaaattta
//
LOCUS       DAEPXW010000038        33588 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.039, whole genome shotgun sequence.
ACCESSION   DAEPXW010000038 DAEPXW010000000
VERSION     DAEPXW010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33588
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.039"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            99..623
                     /locus_tag="KRM55_001795"
     CDS             99..623
                     /locus_tag="KRM55_001795"
                     /inference="COORDINATES: protein motif:HMM:NF016362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HBH1594043.1"
                     /translation="MFRKNIQTEDLIDILSKQTTLMNDVESYKNQRRLEIDRKRYLDN
                     SFSLDQDMNSDRHIFDNIVTGADFELYLKDLFCQLGYEVITTKASGDQGADLIISKNG
                     IKKVVQAKFYSSSVGNKAVQEVIGAIKFYKADLGMVITNNYYTKSAIELASVNNIELI
                     NGDDLIDLRERAFA"
     gene            complement(736..1869)
                     /locus_tag="KRM55_001796"
     CDS             complement(736..1869)
                     /locus_tag="KRM55_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBH1594044.1"
                     /translation="MDFSDKINQFSKRIETLKNNLTTEEATKTALIMPLFQILEYDIF
                     NPLEFMPEFIADVGVKKGEKVDYAILKDGKPLILIEAKCASDKLKKHDAQLFRYFTAT
                     EAKFAILTNGIIYKFFTDLEEKNKMDEKPFLILNLLNMDDNKISHLKKFTKNSFDIDT
                     IFNIASELKYTSLIKSQLNMQLENPSDEFVRFIINDFYNGIKTQNVVEKFRPIVKRSL
                     SQFVNDFMNEKLKLLLENDNEDYEKKKVKDNKKKEKNKIENDLTKKQDENNLPKPEIE
                     PKNNILFTDDELKAIDIIQNILIEKASKNELTSKKICNEVNILYKNDIKNWICKITLS
                     PSNKTICLPNGKNDYLEYRMDDVVDIKELKDDLIFVIEKYKKE"
     gene            complement(2076..2291)
                     /locus_tag="KRM55_001797"
     CDS             complement(2076..2291)
                     /locus_tag="KRM55_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594045.1"
                     /translation="MLKELRKKRRLTQKDLSEKANLSRTYISELERGLYKNINIDVII
                     DLSLALEIDCLILCEYFIEENLKRRKL"
     gene            complement(2734..3081)
                     /locus_tag="KRM55_001798"
     CDS             complement(2734..3081)
                     /locus_tag="KRM55_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594046.1"
                     /translation="MFAKRLKELRIDAGLKQSELAKELDISPSTIGMYEQGRRSADQE
                     TLLKISDFFNVSTDYLLGKSNEREINDFIEKLDSPEDIKNMLKIFTELSEEAQDRMLS
                     IAKVFLEEEKSKK"
     gene            3235..3432
                     /locus_tag="KRM55_001799"
     CDS             3235..3432
                     /locus_tag="KRM55_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011590804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594047.1"
                     /translation="MHNSLVDFRNYKKMTQKEMAKKLGITLTLYSKIELGIRNPSYNF
                     LRKFKLIFRDVNIDEIFFENI"
     gene            3462..4280
                     /locus_tag="KRM55_001800"
     CDS             3462..4280
                     /locus_tag="KRM55_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBH1594048.1"
                     /translation="MKKLKVFKSTAFGEIRVLEIYDEIYFVGKDVAEKLGYSNISDAL
                     IKHVDEDDKKQIAFNDLKELGFIDVGTKGTPIINESGLYSLILSSKLPNAKGFKRWVT
                     NDILPSIRKTGTYNMVNSQSNDSYLIENPIERAKRWIEEQEANQLKIQEKDKVIQLQQ
                     PKVLFADAVLGSENSILVGELAKILKQNGVDTGQNRLFDWLRDNGYLIKRKGEDYNIP
                     TQKSMNLGIMEVKKRVINNPDGSTKVTRTVKITGKGQVYFINKLKSDNKIKLVF"
     gene            4327..4806
                     /locus_tag="KRM55_001801"
     CDS             4327..4806
                     /locus_tag="KRM55_001801"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1594049.1"
                     /translation="MAKIATKALNSIYYKARLECAERNKDMRSREGTSQYLTMDCTKL
                     ARIELGNITPRADEVLQISSVYNAPELINYYCKNQCSIGIKYAQNLEVKSLDRLTIEI
                     LATRNDFEKMTEILLNISEKGSVEEHEKDDFKKYVLNTLNQISKLAQETDLWARKNI"
     gene            4823..5023
                     /locus_tag="KRM55_001802"
     CDS             4823..5023
                     /locus_tag="KRM55_001802"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594050.1"
                     /translation="MMNYKTEEEFQEQLRRTWKALNECGIYTMEEAEKAFENIPSIDI
                     SYMVAPLDFDEIYRIRKEMFGH"
     gene            5042..5269
                     /locus_tag="KRM55_001803"
     CDS             5042..5269
                     /locus_tag="KRM55_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594051.1"
                     /translation="MEGLVLKFDLSKFKVGKAIKISSRKINFEGDCIVIIATSDELNL
                     AYFDECRGCIQYQLLTIEDIQQGDYNIRFLH"
     gene            5289..5540
                     /locus_tag="KRM55_001804"
     CDS             5289..5540
                     /locus_tag="KRM55_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594052.1"
                     /translation="MNTAKIFAISQIKRANIEIERLKDNNETSNINILNWWEGVKIAS
                     ENILKMLEYDIELEASDDFREIMMYQEDLERERPLNVQI"
     gene            5616..5882
                     /locus_tag="KRM55_001805"
     CDS             5616..5882
                     /locus_tag="KRM55_001805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594053.1"
                     /translation="MKSREEIIQVLEEQLFLLNFTTVDEVDLDLKFGQVSALESCIDK
                     HKKEWTLEQFKQHLEENKLKKLYGDYIDGFMKILEQNIKYMEGD"
     gene            5882..6523
                     /locus_tag="KRM55_001806"
     CDS             5882..6523
                     /locus_tag="KRM55_001806"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBH1594054.1"
                     /translation="MDNKNIYIKLMDVRVRFNKLDIKKSGQNKFANFKYFELADFLPQ
                     ATDLLKEAKLCPIVTFTNEYATLTLINGENPSEQIIFTSTMRDLQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITENDSFDAISGKEQFKNNTNLNKFDEENRSNEIKVLSTKQLSR
                     LYAIAYNAGVSKEKLKEKVFKQLGKEIKDLNREEYDMICKAYENVEKREVQNG"
     gene            6516..6713
                     /locus_tag="KRM55_001807"
     CDS             6516..6713
                     /locus_tag="KRM55_001807"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594055.1"
                     /translation="MASYLVYECDRCKNRVNSELELVTMPVLRSCEYDKDVNIMIGRK
                     SFIEVCFNCLICITEEMELVR"
     gene            7429..7530
                     /locus_tag="KRM55_001808"
                     /pseudo
     CDS             7429..7530
                     /locus_tag="KRM55_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
     gene            7554..7919
                     /locus_tag="KRM55_001809"
     CDS             7554..7919
                     /locus_tag="KRM55_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594056.1"
                     /translation="MLKVERYFSGSVINNIIEDDLTLKNYLALYCCIIGVTRNGEEMY
                     PTSEKMLIEFGIERRMKKRKKDIPIKLTNVRTGEEKTFETLDSAACFLRLKHQAVYQT
                     IKKKSKTRSGWKAEYIKEE"
     gene            8204..8443
                     /locus_tag="KRM55_001810"
     CDS             8204..8443
                     /locus_tag="KRM55_001810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594057.1"
                     /translation="MKKYKINFEEKVTLEHEIIVEIPEEISINDICHCIENKCQRVYD
                     IADYVKEFNGRQIDFTEDTCGNTEMLVESYINYKE"
     gene            8566..8763
                     /locus_tag="KRM55_001811"
     CDS             8566..8763
                     /locus_tag="KRM55_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594058.1"
                     /translation="MTKFQKAVFQMVKQEEKENLWQGYENCRVGRSISSSIRIYVKGF
                     KKSGYSVYEVYKFIDDINKYE"
     gene            8791..9207
                     /locus_tag="KRM55_001812"
     CDS             8791..9207
                     /locus_tag="KRM55_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015615683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBH1594059.1"
                     /translation="MSKYNNKKIVIDGIKFDSKDESEYYLYLKEKKENGEIKDFGLQQ
                     KFELQPKFKKDGKSYRAITYTVDFAIYKWNGEVVYIDVKGYSTQQGELRKKLFDYKYQ
                     DKILIWISKSKKYGVDGWIEYDELKKKRKENKKKVA"
     gene            9226..9726
                     /locus_tag="KRM55_001813"
     CDS             9226..9726
                     /locus_tag="KRM55_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594060.1"
                     /translation="MASKVKKEFFMATKKHLENYKQLHINIESLKLQIKNLKECHLGD
                     FMQGLSYDSIPISKTNSINNQVEYELINLEEKIIEKQIELYEMEVLKYTIDSAINNLK
                     PIHKQIIGYRYIEGLEWNLVVDKVYLEERQLRERANQAISSISIALFGKKALIEQEPL
                     FKMLDL"
     gene            10145..10351
                     /locus_tag="KRM55_001814"
     CDS             10145..10351
                     /locus_tag="KRM55_001814"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594061.1"
                     /translation="MNRFEGIYSFAEATKLWNLKDSTLRKAVATGKLVENIDCKKFGR
                     DWVVTIEAMEREYGRLDIIMKDLD"
     gene            10955..11665
                     /locus_tag="KRM55_001815"
     CDS             10955..11665
                     /locus_tag="KRM55_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016298727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1594062.1"
                     /translation="MQDVKEKVKKDYLEGMKQKKISAKYDISLNTLKSWIKRYNWASE
                     KKKGAPINKKGAPFYNKNSVGHGAPKENKNAEKFGFFSKYLPEETQELINEIKNKDKF
                     DILWEQIIIQYAAIIRAQKIMYVKDKEEMIKEVKKERTTEFGEEIQYEFQFSWDRQAS
                     FLNAQSRAMSELRSLIKQYDNMIHKDWNLATEEQKQRIEILKSKIPNKDTININSQIT
                     ALADLINNPVEERIIEND"
     gene            11658..12983
                     /locus_tag="KRM55_001816"
     CDS             11658..12983
                     /locus_tag="KRM55_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008686808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBH1594063.1"
                     /translation="MINYSPLTIRQTEYIKKSKDSWLNVLEGGKRAGKNIINLIAYSM
                     CLEVHPDKLHLVAGVSLGAAKMNIIDSNGFGLQYLFEGRCREGEYKNRDALYIQTLTG
                     EKIVIIAGGGKANDAARIKGNSYGTVYISEVNECHQSFVQEVFDRTLASSKRQLFFDL
                     NPFSPSHWFYRDILDYQDELKNSGENEGYNYSHFTIKDNLSISNQVLKEVLRTYDKTS
                     LWYQADILGRRVAATGRIYTGYKKSEVVIDRNYIKDNNITFIEFSIGIDIGGTDATVA
                     TLTGFTKGYNEIIELDGYYHKQGKNHGYTHDKYAKEIVDKIEEWSHTYPHFLFSTYIF
                     CESADKLFRQALSNELKRRGINIQVTPSYKKDGIVDRIRLVNILINQGRYKIMKHLNK
                     WIEAIENAIWDDDEKSKGNWVRVDDGSYTVDCLDSSEYSIQPFKKRLEV"
     gene            12988..14493
                     /locus_tag="KRM55_001817"
     CDS             12988..14493
                     /locus_tag="KRM55_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003444943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH1594064.1"
                     /translation="MGWLKDMATKTAIKLLNIQPAIDREITIKEPLGFNGNIMKNRIW
                     YRGEPSELDQFFKKTANDLVSKSRFWAAVPSSDFNVRKVHSGIPAMIVERLADIVVAD
                     MDKIELDTEELTNLWTDISKDNHFNKLIGESIIETLVTGDGAFKITVDTDITTNPIIE
                     YYSGERVEYKFKRGRLSEVHFLTEYTKDNSTYTLIEIFGKGYIINKLIDSRGQGVPLN
                     TLDETTELKDITYEGDFLMSVPMMFFKSPKWLGRGKSIFDSKSDSFDALDETISQWVD
                     AIRDGRVKQYIPESLLPKNPVTGEIIKSNSFDNKYIAIASSLAEDSQNTIEIQQPSIN
                     YEAYVSTYASNIDMCLQGIISPATLGIDLKKTDSAESQREKEKTTLYTRGKIIDVLNE
                     VIPEIVSTVLKVNDLLYERTIGEYNPVISFGEYSTPSFDTVVETVGKAKSYGIMSTEM
                     AVDELYGDTMSDEKKAEEVLRIKEENGLMDIEEPATNIDGINDDVVNEDVV"
     gene            14494..16188
                     /locus_tag="KRM55_001818"
     CDS             14494..16188
                     /locus_tag="KRM55_001818"
                     /inference="COORDINATES: protein motif:HMM:NF015461.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594065.1"
                     /translation="MTLNPYDIASIYNDMELDLVKSMKQNMKLHESEELKEGFKWEQW
                     QKTKLREIKKFQKRNKGIIKDYQKIVDGETDKLLKSSFKNGSKRSENFISKTLNKVSS
                     KFKNMFEPKEKSFFKINEDKVFNLIKSVKGDLHNANHAALRKMDDVYRQTIFKSQMYV
                     VNGAMTVNQAVDMATKDFLDKGINCITYKNGRKVNISSYAEMSIRTANQRVTLMGEGI
                     KRDEYGVHTVITSNHTNTCPLCLPWQGRVLIDDVYSKGSSKEGRYPLLSEAMSLGFLH
                     PNCRHHPTTFFPDINEIPKPLTEEEKQDALERYNAEQKQREIERNIRKWKRIEAGNLD
                     IANIEDAHKKLELYQNQMKEHLLKHNYLRRDSWREKLRNDDIISTSKYLDSRNNKLKQ
                     VLSKELEKLTDDEKEVINYYTGFGANKINTALTTGKGMEALKDKIDILDKALAKGVIN
                     EDIIVYRKTIPEYMGIFPKSDKISYKDVERLIGLKIINKGFTSTSLNPFDYPGRNIFM
                     KIKVPKGYNGAMYIKNIAKSKYKYQEEVLFTKGLSYKVTGVKMENNIYYLDAEVVM"
     gene            16185..16472
                     /locus_tag="KRM55_001819"
     CDS             16185..16472
                     /locus_tag="KRM55_001819"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594066.1"
                     /translation="MNKIEEAEEEYEDKVNNLPKVGSGFDCNLGGVVVDMPVCRACKN
                     ERLENGKFSCVVFNTIPQKYNDYESYYCSEFIPNKESVFYRILLDLMERKK"
     gene            16503..16760
                     /locus_tag="KRM55_001820"
     CDS             16503..16760
                     /locus_tag="KRM55_001820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594067.1"
                     /translation="MSKLPKIGSGFDCDFGAVILDPPLCSACKNVFLKNNELSCSMYE
                     EIPKKYIESKNYDCPSFTTNKESCWYPSVKKEIDKFFVENK"
     gene            17316..17630
                     /locus_tag="KRM55_001821"
     CDS             17316..17630
                     /locus_tag="KRM55_001821"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594068.1"
                     /translation="MINKIQVEEMIKYVQWHSACGGEPPSEWWDEFPLIFTEDVDETI
                     EFLTGCNEEEIHCMSQIFEEISSGLQSYKFIEFIKSLQKKFPNIKMELSIYWAEQAIQ
                     ED"
     gene            17733..18053
                     /locus_tag="KRM55_001822"
     CDS             17733..18053
                     /locus_tag="KRM55_001822"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594069.1"
                     /translation="MIDKDKIYSNIDYIESMTQNGAFPNLDKHWHEIVDILSKDLKDT
                     EEFLLNECNEYRIWFISGYFEDISYNFQNEGFIEILKKLEKKYPNSNLKDDIHWAEKA
                     IQKD"
     gene            18178..18774
                     /locus_tag="KRM55_001823"
     CDS             18178..18774
                     /locus_tag="KRM55_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003444953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBH1594070.1"
                     /translation="MNKEQFIALGLTEELAKKAESESLSELKNYIPKIRFDEVNTAKK
                     QLENDIKDRDRQLEDLKINSGNSEELKKQIETLQEENKNKDIKYQEELQDLKLSNAIK
                     LSISGKVHDEELAAGLFDKSKLILGDDGKVAGIEEQLKAIQESKKFLFKEEKQSNPKS
                     GFKFGSDGGSNIDNSNQPSKLSMKDAIQAKIQSQMAKE"
     gene            18796..19755
                     /locus_tag="KRM55_001824"
     CDS             18796..19755
                     /locus_tag="KRM55_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008686815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HBH1594071.1"
                     /translation="MAITLEEASKNVQDDLQIGVIDEFRKSNWILDNLTFDDAVSPTG
                     GGSTLTYSYTRLKTQPTAAFREINKEYIPHEVTKERHSVDLKVFGGSYQIDRVIANMG
                     GIVSEVELQQAQKIKAAQALFNDTFINGDSAVDSKAFDGLEKALAGSSTEYNLGDSSI
                     DLSTSQAITTNYMAFLDMLDEFLTGLDGTPSFIAGNTKLISKLRACARRASMYQTQLN
                     SFGQQIESYGNIPFVDLGAKPGTNDDVVATDTTKGTTSLYVARLGLDGLHGVSMAGVS
                     PVQTWLPDFTTSGAVKTGEVEMSAAIALKASKAAGVFRNIKVK"
     gene            19766..19942
                     /locus_tag="KRM55_001825"
     CDS             19766..19942
                     /locus_tag="KRM55_001825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594072.1"
                     /translation="MAKVIAPNSQYNGLSANVYFQNGIGETTNPILIEWFNEHGYKII
                     DDKLEEKITKSKRK"
     gene            19954..20316
                     /locus_tag="KRM55_001826"
     CDS             19954..20316
                     /locus_tag="KRM55_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015926634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594073.1"
                     /translation="MPYATEEYYKNDYGGNLIEDKKLISKLERASDQIDVLTFNRIVT
                     IGFDSLTEFQRDKIKKAVCIQADFIYKYGEYIDMPLSGYSAGDISLSFNASTINGITT
                     TNEIINYLSQTGLTCRKI"
     gene            20317..20637
                     /locus_tag="KRM55_001827"
     CDS             20317..20637
                     /locus_tag="KRM55_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015926633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594074.1"
                     /translation="MKLPFPRWILVTPVKIYSTYISEDGEPIENLILDGMCNYSEKTK
                     QTLDKERKLITLVGKIICEGDIYPNKILQGYIEIQDNKREIYRVSRTRNPDGSIFSTE
                     IELI"
     gene            21480..21659
                     /locus_tag="KRM55_001828"
                     /pseudo
     CDS             21480..21659
                     /locus_tag="KRM55_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901472.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            21741..22109
                     /locus_tag="KRM55_001829"
     CDS             21741..22109
                     /locus_tag="KRM55_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594075.1"
                     /translation="MSIDIKINNTKINKLKKAQREAAKMTAEALKTEINTMQVVPKQT
                     GVLEESVSINLKLLNKGHLKITYDTPYARRLYYHPEYNFRKDKNKNAQGRWLEVFTEG
                     NKKDFSEKAYYKCYKKLTGV"
     gene            22111..22500
                     /locus_tag="KRM55_001830"
     CDS             22111..22500
                     /locus_tag="KRM55_001830"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594076.1"
                     /translation="MYLKDIKEWLKETISDKNIAFYIGNIDANKEKVIGIYNKDSNSN
                     KIAIGGLINTSTSTKAITVLIHWNKNCDTTEKMSRCIYDLFNGKTVVINKVNAFFIMK
                     NDEPVFLGTDENGIYEYVIDLDIIYER"
     gene            22508..22960
                     /locus_tag="KRM55_001831"
     CDS             22508..22960
                     /locus_tag="KRM55_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015926389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594077.1"
                     /translation="MAGKSGVVPVYDLTFGVNTTGRTGDADTIVKDAESLSVSIDGNI
                     EEWNPMDQGGWTRRLMTSKSLSVSMGGKRNYGDPGNDYIAGLAFKNGQDCNSVFSINF
                     PDGATLKFDCIINVTSMGGDSTATDALEWEALSDGKPIYTPASGSSES"
     gene            22986..23306
                     /locus_tag="KRM55_001832"
     CDS             22986..23306
                     /locus_tag="KRM55_001832"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594078.1"
                     /translation="MSNIIDISTKLTNEKPKIKISEDKVYTVNNSKNTVLIVNQRMSE
                     NNSNEIELIDDALKLLLGEKAFKEIDSMQLSFVDYKTIFIAVMAAISGETYEETEKRF
                     QNSK"
     gene            23248..23640
                     /locus_tag="KRM55_001833"
     CDS             23248..23640
                     /locus_tag="KRM55_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003481432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594079.1"
                     /translation="MLYQEKLTKRQKSDFKTQNKSDGFYDLYEDWELIESSFAKQYGI
                     RLRTEIDMSWSEFCSLLSGIMPETPLGQIVSIRSEKDPKILKGFTKEQRKIRNDWILK
                     RNKKLREDKNNYSSYINNFQNWCKETFS"
     gene            23656..26673
                     /locus_tag="KRM55_001834"
     CDS             23656..26673
                     /locus_tag="KRM55_001834"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594080.1"
                     /translation="MSISVGTINLGLNINQGTFNKQLNGIANGAKSTIGSAFGGLGKM
                     VGVALGATAIAAFGKSCIDLGSDLNEVQNVVDVTFGSMAQDINDFAKTSITQMGMSET
                     AAKRYTGTMGAMLKSSGLSTKQAADMSKTITQLSADMSSFYNLDLEEAFTKIRSGISG
                     EIEPLRQLGINMSVANLEAYAMSKGITKAYQNMSQSEQTLLRYNYLLSVTKDAQGDFV
                     RTQGAWANQTRILSEQFNVLKTTLGQALINMLTPVVKMLNTLILKLQVVAQQFKAFTE
                     SVFGDNASSGSFGSVSKDIESIGNNSDGASDSINGIGDASKNTAKKIKGLISGFDEIN
                     TLTKNSDTEGLGDMGNVTSPIGPNIDTGNLSKVNQELNKMLADMFKPFQDAWSKEGQA
                     TIDSMKYAFTSIKDVIKSIGSSFKEVWTNGTGTEILTTTLQILQNIFNIIGDINNAFI
                     IAWESNNLGTQLIQSISDALLNVLRIIRDIGNSFIEVWNNGTGIEFCTNILNLLKTIF
                     DIIGSIAGAFDIAWKSNETGTILIQTIFNMLNSILELINNIGQTFVEVWNNGTGVEIN
                     TLILQILTDIFGTINEITDAFSIAWESNNIGKQIIQGICDIITNLLTLLHNMQESCRE
                     AWAVVGVPLATTFYEILNAIIGVIENLTGKLVEVWDNGGEHLYLGIVKLAQKIFELVG
                     YVITDFIAPFANGLIDILAPAISFVLDVLGTLADYLTNFIDWLLNEGKPVLDTIIIVL
                     GSMAVAFGVVKAACTVFDTVKKGIDIFNGLKNTISAAGGVMRLIPQVLGTMLGPFGLV
                     VVAVGALIAAGVLLYKNWDTIKKKALEIFGYIKNFISGVCSKIGGFFNSMGTKIKSVI
                     NSIPGVFKKAFNGLANIVKAPLNAVIKLFNSSLGSLKFDIPDWVPGFGGNSFGIPKIP
                     LLAKGGIIEQPTLSMVGERGTEAVVPLENNTQGLDLLASKIMERMNGLGTNNNTSGDL
                     TVELKMDGNKMGEVVIKAFRQMERKTGKTILEL"
     gene            26685..27032
                     /locus_tag="KRM55_001835"
     CDS             26685..27032
                     /locus_tag="KRM55_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594081.1"
                     /translation="MLSINGVDIIAPTVFQVDLTDIDGESNRNAKGEMCRDRIATKRK
                     LNCEWGILDSSEISILLNQVKDVFFKITYPDPVLGHIETKTFYVGDRSMPVALKKDNN
                     IFWQSLKMNFIEK"
     gene            27045..27221
                     /locus_tag="KRM55_001836"
     CDS             27045..27221
                     /locus_tag="KRM55_001836"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594082.1"
                     /translation="MDIKISDRLLYQKALNEVVKLQNDLIIQKAINDEKDTYIIELQE
                     KLAELEECDNNEGN"
     gene            27208..29517
                     /locus_tag="KRM55_001837"
     CDS             27208..29517
                     /locus_tag="KRM55_001837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594083.1"
                     /translation="MKETSQEYKKAILENSRIISSKIIINDEKYTDEDIISINIEESI
                     LNNEKFELGGGIATSVNIEINNYSNKFKDYKFKNKWFELYFYIEIAINEYQSRIEEIY
                     FGKYYIFETELSGKIIKLECYDTLILTDKAYKPNIGFPATVYDIVIDIANILNLKLSD
                     KIVKRRFNNDDLLIEYKPNSDEATYRQVLMDCAVIAGSFLIVKYGEIEFLDLVEANVQ
                     ITGENWFDVTIGSESNKINFVDINGVVAGDPFENGLQLSILLLDYNKENEIREVAQSI
                     LNKYKNFVYTGFSMDWQGDFALDVGDKLIIYDKDDIPKTTFISDNKISYNGGLSSTIE
                     AKIDKEEVRSASRTIQRLDSNLKKLESGFIQTNESIELYVKEITDKQETLESKFEILS
                     GSIEAIVQSTVDEAISKIVIDTEKIVMEVTKKIDGQYIVSTINQSAEKIEMSAINIDL
                     EGYVTFNSLEDEGETRINGSNIITDTLSVDKLKSSTDNPIIHLFVNDERGIDCSIDAT
                     AQYEEGVGDALRYKRDSENYLCIRENSFSLYQSGYPEYEVFTLGNNANSCFIDTVNGK
                     ISFEKDKLYYENAGVKKRVLLDGDSTGGGDSEGEDSGGTTKPPNPAKEAKFFIKEGLG
                     GSSNESLTFSSYDFAFIRTVETEQGTVYRVTGIYSSTSFSEITSELLELSAYKTVKII
                     FNMQYYARSSGVYSMTVGIGCGPQNNSTYMYEKTLEFNDVTDKATIRYNVILTCPFNI
                     QDAFIRFFVRNKEKIDLSIIIDIISWWIE"
     gene            29550..30653
                     /locus_tag="KRM55_001838"
     CDS             29550..30653
                     /locus_tag="KRM55_001838"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594084.1"
                     /translation="MRDKTYTVDLNTKVYSVPIYKQFDNLIPFSIKLIEDGKEIDLSG
                     YTALAFFQNDKVLIQKNCIINDNIVKAILDNNILALPGLIKVEFQFRKNQEIVTTFQM
                     KIQVEESLDKENAIESTPQWDLLGQAIIDITNSINDINETKENLINDINTNISTLNSK
                     IDSSVDTMIQDINVVKENLVDDISELTTKVDERVALEIFDGDYNSLINKPTKVSDFEN
                     DAGYITSSDIDSSQNHVHTNKAVLDGITQDKVTSWDSKSNFDGNYNSLTNKPTKVSDF
                     ENDAGYITNSDIDTSQNHVHSNKIVLDEITQDKVVSWDAKTNFDGDYNSLINKPNLTS
                     KAVTGLNFWVGTQAEYDSVDIKDATTLYLIKEE"
     gene            30658..31098
                     /locus_tag="KRM55_001839"
     CDS             30658..31098
                     /locus_tag="KRM55_001839"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594085.1"
                     /translation="MFVLNKTRISKVRLSEETIKQIFLGDELIFSNKLHKKSFEIGGI
                     KLRNLTCNLDIKNKDKTNIKLNENYLKYSINKINLRCLVDRYNYKIDYPISKELNENY
                     LKYSIGKINLKTLIDIYNYKIDYPISKTFIENYNKFSIGRIKIK"
     gene            31114..32376
                     /locus_tag="KRM55_001840"
     CDS             31114..32376
                     /locus_tag="KRM55_001840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594086.1"
                     /translation="MALKGSATIELTDSQGNKEVYKEDNIITNAVQDLLNINLNGQVM
                     PFKFFPLKDFFSGVLLMDSNIEERPDITTIPSGVEVLGHAGSETNTTTNTLKGSINLT
                     ETKELNNGYKFVWDFSNTQGNGIIKSICLTHLKAGNDNLYNNIVTDVSTYDSDKYWSN
                     DVKYITSIDFENGILYVCKKGSSTTDITIYKYAHNFLSFGINDIYSNIKLIETKVISG
                     TTIGAIKSELSFSDGRDGYLYGFYAPRKASGDTILNIIRISKSDFTYTEKSITLTDVQ
                     LYLPNDFYYVNVCPIKDGFIYLLDYKTKSTFYKMNLTDETDIKLLESDNKKQLISSEG
                     SSFALIGDTLYSKYVTIFNDKVREISKNLIGDAYCIHSYKNYLIRFYSYSVIGYLNGI
                     LTTVNNLSTPIEKTTDKTMKITYIITEA"
     gene            32443..33081
                     /locus_tag="KRM55_001841"
     CDS             32443..33081
                     /locus_tag="KRM55_001841"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594087.1"
                     /translation="MIELKNQKVDKIYLGQRDINKIHIGNNLIYSNSIEIKHNERYGL
                     YMTANNKPEPFEVTSSQNVWGAYRAFTETLSDDLNLTGLSKNTSQWVQIKLDKNIKIW
                     AIKMHFRTTISNQDTAQVPFKFKLLGSNDGSSFTELHNCESCNPDLFCKWKDDISKYD
                     FSDADFIEVSSNSEYQYYRVEFFNTQSISKGNVINTEGTEVKITLLNLYQLE"
     gene            33091..33345
                     /locus_tag="KRM55_001842"
     CDS             33091..33345
                     /locus_tag="KRM55_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594088.1"
                     /translation="MEQLVTELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNVLIEMGIMKIDVQKIKENVLDIKDMLQR"
BASE COUNT        13875 a         3375 c         5824 g        10514 t
ORIGIN      
        1 ataatgatgt atataatata attaaaaaga ttgctgatat agatgattca cttattaata
       61 atgaaaactt tatatattta tattgtatta taatacatat gtttagaaaa aatatacaaa
      121 ctgaggattt aattgatata ttatctaagc aaacaacttt gatgaatgat gtagaaagct
      181 ataaaaatca aagaaggttg gaaattgata gaaaacgtta tttagataat agttttagtt
      241 tggatcaaga tatgaatagt gatagacata tatttgataa tatagtaact ggagcagatt
      301 ttgaattata tttaaaagat ttattttgtc aattaggata tgaggttatt acaactaaag
      361 cttctgggga tcaaggtgca gatttaatta tatcaaaaaa tggaataaaa aaagtagtac
      421 aggctaaatt ttattcaagt agtgtgggaa ataaagcagt acaagaagtt ataggagcaa
      481 ttaaatttta taaggctgat ttgggtatgg taataactaa caattattat acaaaatctg
      541 caatagaatt agcatcagta aataacatag aattaataaa tggagatgat ctaatagatt
      601 taagagagcg tgcttttgca taatatttat aaaattaaat taaaacatat agaataaaat
      661 attcttaaaa agaaacttaa aaagaataaa acattctgga aattttgtgt ttcttataaa
      721 aagagtagat tggaactact cttttttata tttctctatg acaaaaatca aatcatcttt
      781 taattctttt atatctacca catcatccat tctatactct aagtaatcat tttttccatt
      841 aggaagacaa atagttttat tagaaggact caaagttatt ttacatatcc aatttttaat
      901 atcattttta tataatatat taacttcgtt gcatattttt ttagaggtta gctcattttt
      961 agaagctttt tctattaaaa tattttgaat tatatctatt gcttttaatt catcatctgt
     1021 aaataatata ttatttttag gttcgatttc tggtttagga agattatttt cgtcttgttt
     1081 ttttgttaag tcattttcta ttttattttt ttctttcttt ttgttatctt tcactttctt
     1141 tttttcataa tcttcattat cattctctaa taaaagcttt aatttttcat tcataaaatc
     1201 attaacaaac tgagataatg acctttttac aataggtcta aatttttcaa ctacattttg
     1261 agttttaatt ccattgtaaa aatcatttat tatgaatcta acaaattcat cagatggatt
     1321 ttctaattgc atatttaatt gtgattttat taaactagtg tattttaatt ctgatgcgat
     1381 attaaatatt gtatctatat caaaagaatt tttagtaaat tttttcaaat gagatatttt
     1441 attatcatcc atatttaata aatttaatat caaaaatggt ttttcatcca ttttattttt
     1501 ttcttctaaa tcagtgaaga acttataaat tattccgtta gtaagtattg caaactttgc
     1561 ttctgttgct gtaaaatatc taaatagttg agcatcatgc ttttttaatt tatcacttgc
     1621 acattttgct tctattagaa ttaatggttt gccatctttt aatattgcat agtcaacttt
     1681 ttcacccttt ttaacaccta catctgctat aaattcaggc ataaattcca atggattaaa
     1741 aatatcatat tctaaaattt gaaacaatgg cattattaat gctgtttttg ttgcttcctc
     1801 tgtggttaag ttgtttttta atgtttctat tcttttacta aattgattta ttttatctga
     1861 aaaatccata ataaccccct atattataaa tatacatata tagttaataa tatacataaa
     1921 gtaacctatt tatcaacatg ttttatggaa atgtctactt ttatatgtaa aataagttat
     1981 tttatgattt attatacaat cttcatatta attaaataag ataaaaatag agtagtctat
     2041 aattttttat tataatgcta tcaaaatatt taatattata attttcttct ttttaaattt
     2101 tcttcaataa agtactcaca cagaatgaga caatctattt ctaatgcaag tgacaaatca
     2161 ataattacat ctatatttat attcttatat aatccccttt ctagttctga aatgtaagtt
     2221 ctacttaaat ttgctttttc agacaaatct ttttgtgtta atcttctttt ttttcttaac
     2281 tcttttaaca tactaaaacc tccctttact ttaatttata catgttgact tttgtagaat
     2341 tataaagtaa atgacggtga tagcgacatt tttgagtaaa aatatgtgct aaaatgtaat
     2401 taagaaaaat tctatggcaa tagagtgtaa aaaattaact agaattttta atacataata
     2461 gagggggata ctttaaatgg gaaaattaga attgaaagta ttggaattaa atcagatatt
     2521 ggtcgaatta aataaaatta attctgaaaa aataacagaa tattttgaaa tattgctctc
     2581 tatttatgaa aaagatgaat aaataagcta tgaattgcaa ttaatgggta attgtatctg
     2641 gtataattat atttaatatt tttaaataaa aagagatgtt taaaaataat ctgattattt
     2701 ttaaacatct ctctaaattt atataagtaa atattatttt tttgattttt cttcttctaa
     2761 aaacactttt gcgatactca acatcctatc ttgtgcttct tcacttaatt cggtaaagat
     2821 ttttaacata ttttttatat cttctggtga atctaatttt tcaataaagt catttatttc
     2881 tctttcattt gattttccaa gaagataatc tgtagataca ttaaagaaat ctgatatttt
     2941 taataaagtt tcttgatcag cacttcttct accctgttca tacataccta ttgtactagg
     3001 cgatatatct agttctttgg ctaattcaga ctgttttaaa ccagcatcta ttctaagttc
     3061 ttttaatctt tttgcaaaca tcataaaaac tcctttttga attataataa cacaaaaagt
     3121 gtagaaaaaa atattactac acaaaaagta taaaaaaaac ttgacaacac gtattgtgta
     3181 gtatattata gaaatataga aacacaaaac gtgtagtgaa taggaggtgg ttaaatgcat
     3241 aatagtttag ttgactttag aaattataaa aaaatgactc aaaaagaaat ggcaaaaaaa
     3301 ttaggtataa cactaacttt atactctaag attgaacttg gtattagaaa tccaagttac
     3361 aattttttaa ggaaatttaa actgattttt agagatgtga atatagatga aatttttttt
     3421 gaaaatatat aacacgatat gtgtataagg aggcgtttat ggtgaagaaa ttaaaagtat
     3481 ttaaaagtac agcttttgga gaaattagag tattagaaat ttatgatgaa atttattttg
     3541 taggaaaaga tgttgcagaa aagttaggtt attcgaatat aagtgatgct ttgataaaac
     3601 atgttgatga agatgataaa aagcaaatcg catttaacga tttgaaagaa ttaggattta
     3661 ttgatgtggg aacaaaagga actcctatta tcaatgaaag tggactttat tctttaatat
     3721 taagctctaa attaccaaat gcaaaaggat ttaaacgttg ggttactaat gatatattgc
     3781 ctagtattcg taaaactggt acatataata tggtaaattc acaatcgaat gatagctatt
     3841 taatagaaaa tccaatagaa cgtgctaaac gttggataga agaacaagaa gcaaatcaat
     3901 taaagattca agaaaaagat aaagtgattc aattacaaca gccaaaagta ctatttgctg
     3961 atgcagtact aggttctgaa aattcaatac tagttggtga actagcaaaa atattaaaac
     4021 aaaatggtgt agatacaggt caaaatagac tctttgattg gcttagagac aatggatatt
     4081 taattaagcg taaaggtgaa gattataata taccaactca aaaaagtatg aatttaggaa
     4141 taatggaagt taaaaaaaga gtaataaata accctgatgg aagcactaaa gtaactagaa
     4201 cagtaaaaat tactggtaaa ggacaagttt actttataaa caagctaaaa tcagataata
     4261 aaattaaatt agttttttaa aatagattac aaataatcta agtttatctt aaaaggagga
     4321 aaatatatgg caaagatagc aacaaaagcg ttaaacagta tttactacaa agctagatta
     4381 gaatgtgcag aaagaaataa agatatgaga agtagagaag ggacatcaca gtatttaaca
     4441 atggattgta caaaactagc aagaattgaa ttaggaaata taacccctag agctgatgaa
     4501 gtattacaaa tttcaagtgt atataatgca ccagaattaa ttaactatta ttgtaaaaat
     4561 caatgttcga taggaattaa atatgcacaa aatttagaag ttaaaagttt ggataggtta
     4621 accattgaga ttttagcaac tagaaatgat tttgaaaaaa tgactgaaat attactcaat
     4681 atatctgaaa aaggttcagt agaagaacat gaaaaagatg attttaaaaa atatgtatta
     4741 aatacattaa atcaaatttc aaaactagca caagaaactg atttatgggc tagaaaaaac
     4801 atttgatagg aggtgataaa ttatgatgaa ttacaaaaca gaagaagaat ttcaagaaca
     4861 attaagaaga acatggaagg cattaaatga atgtggaatt tatacaatgg aagaagcaga
     4921 aaaagcattt gaaaatattc catcaataga tatatcatat atggttgcac cattagattt
     4981 tgatgaaata tacagaatta gaaaagaaat gtttggccat taatcaagga ggaaaattag
     5041 tatggaagga ttagtattaa agtttgattt aagtaaattc aaagtaggta aggcaataaa
     5101 aataagttca agaaaaatta attttgaagg agattgtatt gtaataatag ctactagtga
     5161 tgaattaaat ttagcttatt ttgatgaatg tagaggatgt atacaatacc aattattaac
     5221 tatagaagat attcaacaag gtgattataa tattagattt ttacattaaa taaaaggggt
     5281 gaatataagt gaatacagct aaaatatttg caataagtca aattaaaaga gctaatatag
     5341 aaattgaaag gttaaaagat aacaatgaga ctagtaatat taatatatta aattggtggg
     5401 aaggtgtaaa aatagctagt gaaaatatac ttaaaatgct tgaatatgat attgaattag
     5461 aagcatctga tgattttagg gaaattatga tgtatcaaga agatttagaa agggagagac
     5521 ctttaaatgt acagatataa gaaaagagcc tctgcaaagg ctcaattcaa aaaacatctc
     5581 aatatcaata taattataac atagagagga ctattttgaa aagtagagaa gaaataattc
     5641 aagtattaga agaacaatta tttttattaa attttacaac agttgatgaa gtagatttag
     5701 atttgaaatt tggacaagta tcagcattag aatcttgtat agataaacat aaaaaagagt
     5761 ggactttaga acaatttaag caacatttag aagagaataa gttaaaaaaa ctttatggtg
     5821 attacataga tggttttatg aaaattttag aacagaacat aaaatatatg gagggagatt
     5881 gatggataac aaaaatatat atattaaatt aatggatgtg agagtcaggt ttaataaact
     5941 agacattaaa aagagtggtc aaaataagtt tgctaacttc aagtattttg agttagcaga
     6001 ctttctacca caagcaacag atttattgaa agaagctaaa ttatgcccta tagtgacttt
     6061 tacaaatgag tatgcaacat taacattgat aaatggagaa aacccatcag agcagattat
     6121 attcacttct acaatgcgag acttacaact taaaggctct aatgaattac aagcactagg
     6181 aggtatagaa acctatcaaa ctagatattt gtatattcag ttacttaata taactgaaaa
     6241 tgatagtttt gatgcaataa gtgggaaaga gcagtttaaa aataatacta acttaaataa
     6301 atttgatgaa gaaaatagaa gtaatgagat taaagtttta tctactaaac aattaagtag
     6361 attatatgca atagcttata atgctggtgt tagtaaggaa aagttgaaag aaaaggtttt
     6421 taagcagcta ggcaaggaaa taaaagattt aaatagagaa gaatatgaca tgatttgtaa
     6481 agcttatgaa aatgtagaaa aaagagaggt gcaaaatggc tagttattta gtttatgaat
     6541 gtgatagatg caaaaataga gttaatagtg aattagaact tgtaacaatg ccagtattaa
     6601 ggtcttgtga atatgataaa gatgtaaata taatgattgg aagaaagagc tttatagaag
     6661 tatgttttaa ttgtttaatt tgtataacag aagagatgga attagttaga taagagggtg
     6721 aataccttga aatatacaat attaggattt agtcagaaaa aagcagtaga attaggtctt
     6781 aatataagag atttacttat attaagatgg tttgtagatt ttttaggaag tggaagaatg
     6841 tcaagaaagg tgattgaagg aattgaatac tattggattg attattcggg agtgatagaa
     6901 gaactgccaa tactttatac agagaagcaa gatacaatat atagaatact taaaaaattg
     6961 gacaaattag atatacttga acatgctact ttaaaacaag gaggaacatg gagttactat
     7021 aaattaggat atagatatat agagctaatt agtaacacta aaagttatca acatgtcgga
     7081 aatatatccg actgctcgga tttaaatccg acccaaacgg atatatttcc gacccaaacg
     7141 gatataaatc cggaacgaaa aacccatcta ctatatcctt ctactatacc ttgtaactat
     7201 actacgcagc caagtgctgt agtgaataaa aataaagaaa taattgaaga aaatacacac
     7261 ctaaaactaa gtgaaaatat gaaaaagaaa gtagtcaatt gggatgaaga tagattatta
     7321 aaagctatac atatctttat aaataaaaac ggtgaggtat tcaatttttt agaaaagata
     7381 tataaggata ataggaactt tattagtcat gatgctggtc aaactactag aaataaattt
     7441 gctaatttta ctgaaactta tgtcaaatat acatctagtg aacttgatga aataatcaaa
     7501 aaaagtcaaa aagaaaagtt tgaaaaatag ttagataggg ggatatataa gctgtgctta
     7561 aagtagaaag atattttagt ggttctgtta taaataatat tatagaagat gatttaacac
     7621 ttaaaaacta tcttgcattg tactgttgca taattggagt aacaagaaac ggagaagaga
     7681 tgtatccaac ttctgaaaaa atgttgatag agtttggtat tgaaagaaga atgaaaaaaa
     7741 ggaaaaaaga tataccaata aaattgacta atgttagaac tggtgaggag aaaacttttg
     7801 aaacattaga tagtgcagca tgttttttaa gattaaaaca tcaagcagtt taccaaacaa
     7861 ttaaaaagaa aagtaaaact agaagtggat ggaaagctga atatattaag gaggaataat
     7921 ggaagtttca aggaccgaat atacaattaa aagagcaaaa gaattatatg ataatggaga
     7981 agatatattt actgcaatag ataaagctag agaggaatat gaggagatgt tgagaaatga
     8041 atattttaac tagtattacg ttaataataa ctagtttcat agtagggaga atttatgagt
     8101 atagactaaa tttaaaagag tgtgaaaatt gtgatatcaa gaattataaa aataaagaat
     8161 aaattatagg tgtaaattct atagaatgga tgtgtgaaat aaaatgaaaa agtataaaat
     8221 caattttgag gaaaaagtaa ctttagaaca tgaaattata gttgaaatac cagaagaaat
     8281 aagtataaat gacatttgcc attgtataga gaataaatgt caaagagtat atgatatagc
     8341 agattatgta aaagagttta atgggagaca aatagatttt acagaagata cttgtggaaa
     8401 cactgaaatg ttagttgaat cctatataaa ttataaggag tgattccatg aaacgaagaa
     8461 gatgcagctg gtgtggtaaa ctattttata ttgacgaaaa atctaaggag atttattgtt
     8521 gtaaggaatg taggaagaag gctaataggg ctaggagcaa agatgatgac taaattccaa
     8581 aaagcagttt ttcaaatggt gaagcaagag gaaaaagaaa atttatggca aggatatgaa
     8641 aattgtaggg taggtagaag tatatcaagt tcaataagga tatatgtaaa aggatttaaa
     8701 aagtctggat atagtgtgta tgaggtttat aaatttatag atgatattaa taagtatgag
     8761 taatttttaa gtgataaagg gagtatttga ttgagtaaat acaataataa gaaaattgta
     8821 atagatggaa ttaaatttga tagtaaagat gagtcagagt attatttata tttaaaagaa
     8881 aaaaaggaaa atggagaaat aaaagacttt ggacttcaac aaaagtttga actacaacct
     8941 aagtttaaaa aagatgggaa aagctataga gctattacat atacagttga ttttgccata
     9001 tacaaatgga atggtgaagt cgtttatata gatgtgaaag ggtatagtac acagcaaggt
     9061 gaacttagaa aaaagctttt tgactataag tatcaagata aaatacttat atggatttct
     9121 aagagtaaaa agtatggggt agatggttgg atagaatatg atgaacttaa gaaaaaaaga
     9181 aaggaaaata aaaagaaagt agcttagata aataggggtg atgttatggc aagtaaagtt
     9241 aaaaaggagt tttttatggc aactaaaaag caccttgaga actacaaaca attacatatt
     9301 aatattgaaa gtctaaaact tcaaataaaa aatcttaaag agtgccattt aggtgatttt
     9361 atgcaaggct taagctatga cagcattcct ataagtaaga ctaattcaat aaacaatcaa
     9421 gttgaatatg agttaattaa tcttgaagaa aagataatag aaaaacagat agagctatat
     9481 gaaatggaag tactaaaata tacaatagat tcggctataa acaatctaaa gccaatacat
     9541 aaacaaatta taggatatag atatattgag ggattagaat ggaatttggt ggttgataaa
     9601 gtatatttag aagaaagaca attaagagag agagctaatc aagctattag ttcaatatca
     9661 atagctttat ttggtaaaaa ggcattaata gagcaagaac cattatttaa aatgttagat
     9721 ttataggcag ttaataactg tctatttttt tgcaaaagat atatggaaat cattgacaat
     9781 atcacgcata cgtgatataa ttaaagtata gaaaggaggt gaaaagtaag tggctaagaa
     9841 aataaaagag ttcagaaaac tcataaaaga attaactgaa ctcgtactcg aagttggcac
     9901 actattagca gtcattaaaa tggtaataga tagcctacat tagtaaaacg ttaagagtgg
     9961 aagttgcacc ttccctctta actaaattat aaaacatagt cactgaaaat acaatgaata
    10021 agtacagaga gttaacattt gaattattga aattactgta tgacactatt aaattaattg
    10081 gagcattact cttgttatat tatgttatta actcaatttt ctaacaatga ttaggaggaa
    10141 ttttatgaat cgatttgaag gtatttatag ctttgcagaa gcaacaaaat tatggaattt
    10201 gaaagattct acacttagaa aagcagttgc gacaggcaaa ttagttgaaa atattgattg
    10261 taaaaaattt ggtcgtgatt gggtagtgac tattgaagca atggaaagag aatatggaag
    10321 attagatatt ataatgaaag acctagatta aattctaggt cttttaatcg ccgtttttct
    10381 gccgatttta taatttaaaa tgtgagataa tagtattgtg gaaatgaata tttccctctc
    10441 aaaactaaat atatatgtga gctaggttaa gggattcacc tagcttatat gaacagacta
    10501 ggcagggcat gaggatgctg taagttcaat tcttactatg ttcaaaatat ttttattaat
    10561 acactatatg tagcagttga atttagatta aaatctcata caattttgta tcttaattca
    10621 ggtgtctaaa agagtggggc ttggtaacct cactcaatgt ataagtgctg gtgcataatt
    10681 ctaggttcaa ttcctagaac ttattccttt aaatataata tgtatccccc attaaaaaga
    10741 cttagattaa tttctaggtt ttttatattc ttatatttta aaaattagat tttatactaa
    10801 ataaattagg gaaagagcta agaagaaagg ttattaagat taaaaaagaa ctagaaaaag
    10861 aaattgaaga agaaaaaatt atatagattt tttataaaga ctctaacaag agtccttttt
    10921 tattatcaaa acaaacaaat aaagaggtgg tgatttgcaa gatgtcaaag aaaaggtaaa
    10981 aaaagattac ctagaaggta tgaaacaaaa gaaaatatca gcaaagtatg acattagttt
    11041 aaatactcta aaatcatgga taaaaagata taactgggct agtgaaaaaa agaaaggtgc
    11101 acctataaac aaaaagggtg caccttttta taataaaaat tcagttggac atggtgctcc
    11161 aaaagagaat aagaatgctg agaaatttgg gttcttctca aaatatctac ctgaagaaac
    11221 tcaagaatta attaatgaga taaaaaataa agataagttt gatattcttt gggaacagat
    11281 aataattcaa tatgcagcaa taataagagc acaaaagata atgtatgtta aagataaaga
    11341 agaaatgata aaagaagtta aaaaagaaag aacaacagag tttggagaag aaatacaata
    11401 tgaatttcaa ttctcgtggg atagacaagc ttcttttctt aatgcccaat caagagctat
    11461 gagtgaactt aggagcctta taaagcagta tgataatatg attcataaag attggaatct
    11521 agcaacagaa gaacaaaaac aaagaattga aatattaaaa tctaaaatac caaataaaga
    11581 tactattaat atcaattcac aaataacagc ccttgcagat ttgataaata atccagtaga
    11641 agaaaggatt atagaaaatg attaactatt ctccactaac aataagacaa acagagtaca
    11701 taaagaaaag taaagatagt tggttaaatg ttttagaggg tggaaaaaga gctgggaaga
    11761 acattataaa tttgatagct tattctatgt gtttagaggt tcatccagat aaattacatt
    11821 tagtagcagg tgtttcacta ggagctgcta agatgaacat tatagatagt aatggttttg
    11881 gtttacagta tctatttgaa ggtagatgta gagaaggtga atataaaaat agagacgcat
    11941 tatatattca aactttaact ggagagaaga ttgtcattat tgcaggtgga ggaaaagcaa
    12001 atgatgcagc aagaataaaa gggaactcat atggaacagt ctatatatca gaagtaaatg
    12061 agtgtcatca atcatttgta caagaggttt ttgatagaac actagcaagt agcaaaagac
    12121 agttattctt tgatttaaat ccattttcac caagtcattg gttttataga gatatattag
    12181 attatcaaga tgaattgaaa aatagtggag agaatgaggg gtataactat tcacatttca
    12241 ccataaaaga taatttaagc ataagtaatc aggtattaaa agaagttcta agaacctatg
    12301 ataaaacatc actttggtat caagctgata tattagggag aagagtagca gcaacaggaa
    12361 gaatatatac tggatataaa aagagtgaag ttgttataga tagaaattat ataaaagaca
    12421 ataatataac atttattgag tttagtatag gaatagatat tggtggtaca gacgcaactg
    12481 tagccactct aacaggtttt actaaaggtt ataatgagat tatagagtta gatggatatt
    12541 atcataaaca aggaaagaat catggttata cacatgataa atatgcaaaa gaaatagtcg
    12601 ataagattga ggagtggtca catacctatc ctcatttttt attttctaca tacatattct
    12661 gtgaaagtgc agataagtta tttagacaag ctctaagtaa tgaactgaag cgaagaggta
    12721 taaatataca agtaacacca agttacaaaa aagatgggat agtagataga ataaggcttg
    12781 taaatatact aataaatcaa gggcgatata agattatgaa acatttaaat aaatggatag
    12841 aagctattga aaatgcaata tgggatgatg atgaaaagtc aaagggaaat tgggttcgtg
    12901 ttgatgatgg aagttatact gttgattgcc tagatagttc agagtattca atacaaccat
    12961 ttaaaaagag attggaggtt taagaatgtg gggtggttaa aagatatggc tactaaaaca
    13021 gctataaagt tacttaatat acaaccagct attgatagag aaattacaat aaaagagcca
    13081 ttggggttta atggtaatat aatgaaaaat agaatttggt atagaggaga accttctgaa
    13141 ttagaccaat tttttaaaaa aactgccaat gatttagtaa gtaagtctag attttgggca
    13201 gctgtaccta gttctgattt taatgttaga aaagtacatt caggtattcc tgctatgatt
    13261 gttgagagat tggcagatat agttgtagct gatatggata aaatagaact tgatacagaa
    13321 gaattgacta atttatggac tgatataagt aaagataatc attttaataa acttattgga
    13381 gaatctatta ttgaaacttt agtaacagga gatggagctt ttaaaataac agtagataca
    13441 gatataacta ctaatccaat tatagaatat tatagtggtg aaagagtaga gtataaattt
    13501 aaaagaggta gactatctga agtacacttt cttacagaat atacaaagga taattcaaca
    13561 tacactttaa ttgagatatt tggaaaagga tacataataa ataaattgat tgatagcaga
    13621 ggtcaaggcg ttccattaaa tactttagat gaaactacag agttaaaaga tatcacctat
    13681 gagggtgatt ttttaatgtc tgtacctatg atgtttttta aatcacctaa atggttaggt
    13741 agagggaaaa gtatatttga tagtaagtca gacagctttg atgctttaga tgaaactata
    13801 agtcaatggg tagatgctat tagagatgga agagttaaac aatatatacc agaaagttta
    13861 cttcctaaga atccagtaac aggagaaatt attaaatcca attcatttga taataaatat
    13921 atagctatag catctagttt agctgaagat tctcaaaata caatagaaat tcagcaacca
    13981 tcaattaatt atgaagcata tgtaagtacc tatgcaagca atatagatat gtgtttacaa
    14041 ggtattatat cacctgccac tcttggtatt gatttgaaga aaacggatag tgcagaatca
    14101 caaagagaaa aagaaaaaac aactctatat actagaggta aaataataga tgttttaaat
    14161 gaagttatac cagagatagt atcaactgta cttaaagtta atgatttatt gtatgaaaga
    14221 actataggag aatataatcc agttataagt tttggtgaat actcaacacc aagttttgat
    14281 acagtagttg aaacagtagg taaagctaaa agttatggaa taatgagcac agaaatggct
    14341 gtagatgagc tttatggtga tactatgagt gatgaaaaga aagcagaaga agttcttagg
    14401 ataaaagaag agaacggact aatggatata gaagaaccag caactaatat agatggaatt
    14461 aatgatgatg tagtcaatga ggatgtggtc tagttgactt taaatccata tgatatagca
    14521 tctatttata atgatatgga acttgattta gtgaagtcaa tgaaacaaaa catgaaactg
    14581 catgagtcag aagaattaaa agaaggtttt aagtgggaac aatggcagaa aactaaatta
    14641 agggaaataa agaaatttca aaagagaaat aaaggtataa taaaagatta tcaaaagata
    14701 gttgatggag aaacagataa attactaaaa tctagtttta aaaatgggtc taaaaggtca
    14761 gaaaatttta ttagtaagac gctaaataaa gtaagttcta aatttaaaaa tatgtttgaa
    14821 cctaaggaaa agagcttttt taaaataaat gaagataaag tttttaatct tattaaatct
    14881 gttaaaggtg atttacacaa cgcaaatcat gctgcactta gaaaaatgga tgatgtatat
    14941 agacaaacaa tatttaaatc tcaaatgtat gtagttaatg gagcaatgac agtaaatcaa
    15001 gcagtagata tggctactaa agatttttta gataaaggaa taaattgtat tacatataaa
    15061 aatggcagaa aagtaaatat atctagttat gcagagatga gtataagaac agctaatcaa
    15121 cgtgtaacat taatggggga aggcataaaa agagatgagt atggagtaca tacagtcata
    15181 acatcaaatc atacaaatac ctgtccatta tgtttacctt ggcaaggaag agtattaatt
    15241 gatgatgtat atagtaaagg aagttcaaaa gaaggaagat atcctttatt aagtgaagct
    15301 atgtctctag gttttttaca tccaaactgt agacatcatc caactacatt ttttcctgat
    15361 attaatgaaa ttcctaaacc tttgacagaa gaagaaaaac aagatgctct tgaaagatat
    15421 aatgctgagc agaaacaaag agaaattgaa agaaatataa gaaaatggaa aagaatagaa
    15481 gctggtaact tagacattgc taacattgaa gatgcacata agaagttaga attatatcaa
    15541 aatcaaatga aggagcattt attaaagcat aactatttaa gaagagattc ttggagagaa
    15601 aaattaagaa atgatgatat aattagtaca tcaaaatatt tagattccag aaataataaa
    15661 ttaaaacaag ttttatcaaa agaattagaa aaattaactg atgatgaaaa agaagtaatt
    15721 aactattata caggatttgg agccaacaaa attaatactg ctttgacaac aggtaaagga
    15781 atggaagctc taaaagataa aatagatata ttagataagg ctttagctaa aggagttatt
    15841 aatgaagata taattgtata tagaaaaact atcccagagt atatgggaat atttcctaag
    15901 agtgacaaaa taagttataa ggatgtagaa agattaattg gacttaaaat aattaataaa
    15961 gggttcacat ctacaagctt aaatccattt gattatcctg gaagaaatat atttatgaag
    16021 ataaaagttc caaaaggata taatggtgct atgtatataa agaatatagc aaagtctaaa
    16081 tataaatatc aagaagaagt tttatttaca aaaggattga gttataaagt gacaggtgtt
    16141 aaaatggaaa ataatattta ttatttggat gcggaggtag taatgtgaat aaaatagaag
    16201 aggcagaaga agaatatgaa gataaggtta ataatttgcc aaaggtaggg agtggatttg
    16261 attgtaactt gggaggcgta gttgtagata tgccagtttg tcgtgcttgt aaaaatgaaa
    16321 gattagaaaa tggaaaattt tcctgtgttg tatttaacac tatacctcaa aaatataatg
    16381 attatgaatc ttattattgt tcagagttta ttccaaataa agaaagtgtt ttttatagaa
    16441 ttttgttgga tttgatggaa agaaaaaagt aattaataat atttatacat agaggtgata
    16501 aaatgagtaa attacctaaa ataggaagtg gatttgattg tgattttggt gcagttatct
    16561 tagatcctcc tttatgcagt gcttgtaaaa atgtgttttt gaaaaataat gaattgagtt
    16621 gctctatgta tgaagaaatt cccaagaaat atattgaaag taaaaattat gattgtccaa
    16681 gttttacaac aaacaaagaa tcttgttggt atccttctgt gaaaaaagaa atagacaagt
    16741 tttttgttga aaataaataa gtttaaacta aaaaattaat ctaacccata tactttttta
    16801 tatttatttt attgttttac tcctaagtag aattttttaa aagaattgag ttataaatta
    16861 gaattaaaga aaatgcattt attgtttgga taaggagaga acaaggtgaa taaaagataa
    16921 gaatgaagaa gaaagaatac agacataaga tagttaaact accaaaagta ggaagtgaat
    16981 ttgattgtag tttagaaaca gttgtgacag gcataccact atattgagct tgtaaaaatt
    17041 aaatatcaga aaatagaaaa ttctcttgta tcatatttaa tattgtacat tagaaatgta
    17101 acaattatga atcctattat tatgcagagc ttattccaga taaagatggt aatttttatc
    17161 aaattttatt cgaattaact gaaaagaata aataattaat attctttgta ggtatatata
    17221 ataagattaa ttacttgtct aaagtatgaa atagatttaa ttgtaacttt gatataattt
    17281 aataaaaatc aaatactgtt aaaaggatga tcataatgat taataaaatt caagtagaag
    17341 agatgataaa atatgtacaa tggcattctg cttgtggtgg agaacctccc agtgaatggt
    17401 gggacgaatt tccattaatt ttcacagaag atgtagatga gactatagaa tttttaactg
    17461 gttgtaatga agaagaaatt cattgtatga gtcaaatttt tgaagaaata tcaagtggac
    17521 tacaaagtta caagtttata gagtttatta agagtttaca gaaaaagttt cctaatataa
    17581 aaatggagct aagtatttat tgggcagaac aagccataca agaagattaa gttatttgat
    17641 ataagattga cttgtgaata ctaaataaat aaattaaaaa gaaaagaatc attttttaaa
    17701 taaaatgcaa aaaatattag gaagtgatta cattgattga taaagataaa atatatagta
    17761 atatagatta tatagagtcc atgacacaaa atggagcatt tcctaatttg gataaacatt
    17821 ggcatgaaat tgttgatata cttagcaaag atttaaaaga tactgaagaa tttttattaa
    17881 atgaatgtaa tgagtataga atttggttta tcagtggata ctttgaagat atttcatata
    17941 attttcaaaa tgaaggtttt attgaaatct taaaaaaact tgaaaaaaag tatcccaatt
    18001 ccaatttaaa ggatgacatt cattgggcag agaaagctat acaaaaagat taagcacata
    18061 cttaaaacta agtaggtgct ttttttatcg ccattttgtt gttttgggcg ttaactataa
    18121 actcatcact gggcaagacc aggttaaaaa atgaagatga aaagggagaa agataaaatg
    18181 aataaagaac aatttattgc attaggattg acagaagaac ttgctaaaaa ggcagaatca
    18241 gaatcacttt cagaacttaa aaattatata cccaaaataa gatttgatga agtaaataca
    18301 gctaaaaaac aacttgaaaa tgatataaaa gatagagata gacaattaga agatttaaaa
    18361 ataaatagtg gcaattcaga agaattaaaa aaacaaattg aaacactaca agaagaaaat
    18421 aaaaataagg atattaaata tcaagaagaa ttacaggatt taaaacttag taatgccatt
    18481 aagttatcaa tatcaggtaa agttcatgat gaagagttag cagcaggttt atttgataaa
    18541 tcaaaattaa ttttgggtga tgatggaaaa gttgctggaa tagaagaaca actaaaagct
    18601 attcaagaat caaaaaaatt tttatttaaa gaagaaaaac aaagtaaccc taagtcaggt
    18661 tttaaatttg gtagtgacgg aggaagtaat atagataact ctaatcaacc aagtaaatta
    18721 agtatgaaag atgctataca agcaaaaata cagtctcaaa tggctaaaga gtaattttaa
    18781 aggaggaaaa taaatatggc aattacatta gaagaagcta gtaaaaatgt acaagatgat
    18841 ttacaaatag gtgttataga tgaatttaga aagtcaaact ggattttaga taacttaaca
    18901 tttgatgatg ctgtttcacc aactggagga gggtctacac ttacttattc ttatacaaga
    18961 cttaaaacac agccaacagc agcatttaga gaaataaaca aagaatatat accacatgaa
    19021 gtaactaaag aaagacattc tgttgattta aaagtatttg gaggtagcta ccaaatagat
    19081 agagttatag ccaatatggg tggtattgta tcagaagtgg agcttcaaca agcacaaaaa
    19141 ataaaagcag ctcaagcact ttttaatgat acatttataa atggtgatag tgcagtagat
    19201 tcaaaagcat ttgatggttt agagaaagct ctagctggaa gttcaacaga atataattta
    19261 ggtgatagtt ccatagactt atctacttca caagctatta caacaaatta tatggcattt
    19321 ttagatatgt tggatgagtt tttaacaggt ctagatggaa ctccatcatt tatagcagga
    19381 aatactaaat tgatatctaa gttaagagca tgtgcgagaa gagcaagtat gtatcaaaca
    19441 caattaaata gttttggtca acaaatagaa tcatatggaa acataccatt tgttgatttg
    19501 ggagcaaagc ctggtacaaa tgatgatgta gtagctacag atactacaaa aggaacaaca
    19561 tcattatatg ttgcaagact tggtttagat ggtctacatg gagtatcaat ggcaggtgta
    19621 tcacctgtac aaacatggtt accagatttc actacttctg gtgcagtaaa aacaggagaa
    19681 gttgaaatga gtgcagcaat agctttaaaa gcatcaaaag cagctggagt ttttagaaat
    19741 ataaaagtta aatagggagg attagatggc taaagtaata gcaccaaata gtcaatataa
    19801 tggtttaagt gccaatgtat attttcaaaa tgggattggt gaaactacta atcccatttt
    19861 gattgaatgg tttaatgagc atggctataa gataatagat gataagttag aagaaaaaat
    19921 aactaaatca aaacgtaaat aggaggtgat aaagtgcctt atgcaacaga agaatactat
    19981 aaaaacgatt atggtggaaa tcttatagaa gataaaaagt taattagtaa actagaaaga
    20041 gcttctgacc aaatagatgt tttaacattc aatagaattg ttactatagg ttttgatagt
    20101 ttaacggaat ttcaaagaga taaaataaag aaagctgtgt gtatacaagc cgatttcata
    20161 tataagtatg gagaatatat tgatatgcct ttaagtgggt attcagcagg ggacatatct
    20221 ctaagtttta atgcaagtac tataaatggt ataaccacta caaatgaaat aattaattat
    20281 ttatctcaaa caggtcttac ttgtaggaaa atatagatga agctaccatt tcctaggtgg
    20341 attttagtta cgcctgttaa aatatatagt acttatataa gtgaagatgg agagcctatt
    20401 gaaaatttga tacttgatgg tatgtgtaac tattctgaaa aaacaaaaca aactttagat
    20461 aaagaaagaa agcttataac tttagttgga aagattattt gtgaaggtga tatttatcca
    20521 aataaaatat tgcaaggata tattgaaata caagataata aaagagaaat ttatagagtt
    20581 tcaaggactc gtaatccaga tggttcgatt ttttctactg aaatagaatt aatttaaaaa
    20641 aaatatctca ttttaacata gtatgtgata ttattctgtt aaagggggag atttttatga
    20701 taatatcaaa tgaagaattg aaattgataa agaaagaagc aggtggatta ttagggacag
    20761 tgagtggaat ctatgcagag tattgtggag gagtatatgg attaaaggaa aatacaaaag
    20821 gacaactatt gttactaaaa aatggatttt cgtttgacac tttatctcaa aaaaagctat
    20881 ttattccact tgataatgta attaaaattt atagatacaa taatgtgatg tttatagagt
    20941 ttatagaaga agaaaatcag tatagagttg aatttaaagc aaaaaacatt gataagataa
    21001 aagagataac agaagccatt aagcgattaa ctggagatat agagatagaa aaacttcaat
    21061 ctagaaagca actagaggat attccggtag gagataagtt catatactca aatgattcta
    21121 aaggaattaa tgtaaaagaa tataaagaag aaaaagaatt atcctattta tctctaacag
    21181 atatagatat agcttccatt atagaagaat gtggatataa taaagttaac tctataaaac
    21241 aaataaataa attaactaat ttaagtttga ctcagtgtaa aaagatagtt gatgattatt
    21301 ttataaataa taatttgggg aatatagaaa aatatgatgc aataaaagat tttaataatg
    21361 aaaaaaaaca tgaggataaa attaaaaaac ttcaagaaaa acaacttaaa cttgaaatga
    21421 aaaatacaaa actaaatata aaacaacaaa aaaatgctat aaaacaggat aaaaaaacag
    21481 ctcgttgccc taagtgtggc tcaacgtctc tatcagcaca taaaaaaggt tttggtatag
    21541 ggaaagctgt tgttggaaca ttagttactt ctaatcttat tggtcttgtt gctggaaatg
    21601 caaatgctaa aaaagttaga gttacatgtc taaaatgtgg caaacagttt tgggcataat
    21661 aattattaaa gagtacttgt tttatcaagt acttttttat tttggagttg gtggtaatta
    21721 aaaatccatt tagaagtaaa ttgagtattg acataaaaat aaataatacc aaaattaata
    21781 aattaaaaaa agctcaaaga gaagctgcta aaatgacagc agaagcttta aaaacagaaa
    21841 ttaatacaat gcaagttgta ccaaaacaaa caggagtact tgaagaatct gtaagcataa
    21901 atttgaagtt acttaataaa ggtcatctta aaataacata tgatacaccc tatgctagac
    21961 gtttatatta tcatcctgag tataatttta ggaaagataa aaataagaat gcacaaggta
    22021 gatggttaga agtctttaca gaaggaaata aaaaagattt ctcagaaaaa gcatattata
    22081 aatgctataa aaagttaact ggagtgtaaa atgtatctta aagatattaa agaatggtta
    22141 aaggaaacca taagcgataa aaatattgca ttttatattg ggaatataga tgctaataaa
    22201 gaaaaagtaa taggtatcta taataaagat agtaatagta ataaaatagc tataggtgga
    22261 cttataaata catcaacatc cactaaagct attacagttt taattcactg gaataaaaat
    22321 tgtgacacaa ctgaaaagat gtctagatgt atttatgatt tatttaatgg taaaacagtt
    22381 gtcattaata aagtaaatgc tttttttatt atgaaaaatg atgaaccagt atttttaggt
    22441 actgatgaaa atggaattta tgaatatgta attgatttag atataattta tgaaaggtag
    22501 tgattaaatg gctggaaaaa gtggagtagt acctgtatat gacttaacat ttggagttaa
    22561 tacaactggt agaactggtg atgcagatac tattgttaag gatgcagaat cattaagtgt
    22621 tagtattgat ggaaatatag aagaatggaa tcctatggat caaggcggat ggacaagaag
    22681 gttaatgaca tctaagtctt tatcagtatc tatgggagga aaaagaaatt atggagaccc
    22741 cggcaatgac tatatagcag ggcttgcttt caaaaatgga caagattgta atagtgtatt
    22801 ttcaattaat tttccagatg gagcaactct taagtttgat tgtataataa atgtaactag
    22861 catgggtggc gattctactg ctacagatgc attagagtgg gaagccttaa gtgatgggaa
    22921 accaatatat acacctgcat caggttctag tgaaagttag aaatattaat aagaggagtt
    22981 aaagtatgtc aaatataata gatatatcaa caaaattaac gaatgaaaaa ccaaagataa
    23041 agatatcaga agataaagta tatactgtaa ataatagtaa aaatactgtt cttatagtaa
    23101 atcaaagaat gtctgagaat aattcgaatg aaattgagct tatagatgat gctttgaaat
    23161 tattacttgg agaaaaagca ttcaaggaaa tagattcaat gcagctttca tttgtagatt
    23221 acaaaactat atttatagca gttatggctg ctatatcagg agaaacttac gaagagacag
    23281 aaaagcgatt tcaaaactca aaataaatct gatggatttt atgatttata tgaagattgg
    23341 gaattaatag aatcaagttt tgcaaaacaa tatggaataa gactccgaac tgaaattgat
    23401 atgtcttggt cggagttttg ttctttattg tctggaatta tgccagagac acctcttggt
    23461 caaatagtat caattagatc tgaaaaagac cctaaaatat taaaaggttt tactaaagag
    23521 caaagaaaga taagaaatga ttggatatta aaacgtaata aaaaacttag agaagataaa
    23581 aataattatt cttcttatat aaataacttt cagaattggt gcaaggaaac ctttagttag
    23641 aagggaggtg catagatgag tattagtgta ggtactataa atttaggctt aaatataaat
    23701 cagggaactt ttaataaaca attaaatggt atagcaaatg gagctaaatc aacaattgga
    23761 agtgcttttg gtggattagg taaaatggta ggagtagctt taggtgcaac tgcaatagct
    23821 gcatttggta aatcatgtat tgatttaggt tctgatttaa atgaagtaca gaacgtagta
    23881 gatgttacct tcggaagtat ggcacaagat attaatgatt ttgctaaaac ttctataact
    23941 caaatgggta tgtcagagac agctgctaaa agatatactg gaactatggg tgctatgctt
    24001 aaaagttctg gattatcaac taagcaagct gctgatatgt ctaaaactat aacacaatta
    24061 tctgctgata tgtcttcatt ttacaatctt gatttagaag aagcatttac aaaaattaga
    24121 agtggtattt caggggagat agaaccttta agacaattag gtattaacat gtcagttgct
    24181 aatttagagg catatgcaat gtcaaaagga ataactaaag catatcaaaa tatgagtcaa
    24241 tcagaacaaa ctttgctcag atataattat ttactaagtg ttacgaaaga tgcacagggc
    24301 gactttgtca ggactcaagg agcttgggca aatcagacta gaatactttc agagcaattc
    24361 aatgttttaa aaactacatt aggtcaagct cttattaata tgcttacgcc agttgtaaaa
    24421 atgctaaata cacttatact taaactacaa gttgtagcac aacaatttaa agcttttaca
    24481 gaatctgttt ttggtgataa tgcatcatct ggtagttttg gttctgtatc aaaagatatt
    24541 gaatcaattg gaaataactc tgatggtgca agtgattcaa taaatggtat tggtgatgca
    24601 tcaaaaaata cagcaaaaaa aataaaagga ttaataagtg gttttgatga gataaataca
    24661 ctaactaaaa attcagatac tgagggccta ggagatatgg gaaatgtaac ttcccctatt
    24721 ggtcctaata tagatacagg aaatttatca aaagtaaatc aagaattaaa taaaatgtta
    24781 gctgatatgt ttaagccatt tcaagatgct tggagtaaag aaggccaagc aactattgat
    24841 agcatgaaat atgcatttac aagtataaaa gatgtaataa aatcaatagg ttcctcattt
    24901 aaagaagtat ggacaaatgg tacaggaaca gaaatattga ctactactct tcagatactt
    24961 caaaatatat ttaatattat aggagatatt aacaatgctt ttataatagc ttgggaatct
    25021 aacaatttag gaactcaatt aattcaaagt atatcagatg ctttattaaa tgttttaagg
    25081 attattaggg atataggtaa ctcttttata gaagtttgga ataatggtac aggtattgaa
    25141 ttttgtacaa atatacttaa cttacttaaa accatatttg atattatagg aagtattgca
    25201 ggtgcatttg atatagcttg gaagagtaat gaaacaggaa caatattaat acaaaccata
    25261 tttaatatgt taaattctat tttagagttg ataaataata taggtcaaac ttttgttgag
    25321 gtatggaaca atggcacagg ggtagaaata aataccttga tacttcaaat actaacagat
    25381 atctttggaa ctataaatga aattacagac gcatttagta ttgcatggga aagcaataat
    25441 atcggaaaac aaataattca aggaatatgt gatattataa ctaatttgct tacactacta
    25501 cataatatgc aagaaagttg tagagaagct tgggcggttg taggcgttcc gcttgcaacg
    25561 actttttatg aaattttaaa tgccattata ggtgtaattg aaaacttaac aggaaagtta
    25621 gtagaagttt gggataatgg aggagagcat ttatatctag gaattgtaaa actagcacaa
    25681 aaaatctttg aactggtagg atatgttata acagatttta tagcaccttt tgctaatggt
    25741 ttaatagaca tattagcacc agcaatttct tttgttttag atgtgttagg aactcttgct
    25801 gattatttaa ctaatttcat agattggtta ttaaatgaag gtaaaccagt tttagatacc
    25861 ataataattg ttcttggaag tatggcagtt gcttttggag ttgtaaaggc tgcatgtaca
    25921 gtatttgata ccgttaaaaa aggaatagat atatttaatg gattaaaaaa tacgatatca
    25981 gcagctggtg gagtcatgag gttaattcca caagttttag gaacaatgtt aggtccattt
    26041 ggtttagttg ttgttgcagt aggagcactt atagcagcag gggtactttt atataaaaat
    26101 tgggacacaa taaaaaagaa agctttagaa atatttggtt atataaagaa ttttataagt
    26161 ggcgtatgta gtaaaattgg tggatttttt aattcaatgg gaactaaaat aaaatcagtt
    26221 ataaatagta taccaggtgt gtttaaaaaa gcatttaatg gtttagccaa tatagtaaaa
    26281 gcaccactta atgctgttat aaaactattt aatagcagtt taggaagtct taaatttgat
    26341 attccagatt gggttcctgg ttttggaggt aattcttttg gtatacctaa aatacctctt
    26401 cttgcaaagg gtggtatcat tgaacaacca acattaagta tggttggaga aagaggaaca
    26461 gaagctgtag taccacttga aaataataca caaggacttg atttattagc aagcaaaatt
    26521 atggaaagaa tgaatggatt aggaacaaat aataatacaa gtggagattt aacagtagaa
    26581 ttaaaaatgg atggaaataa aatgggtgaa gttgtaataa aagcatttag acaaatggaa
    26641 agaaaaacag gtaaaacaat attagaatta taaggagttg tgatatgtta tctataaatg
    26701 gtgtagacat aattgctcct acagtttttc aagtagattt aactgatata gatggagaaa
    26761 gtaatagaaa tgcaaaaggt gagatgtgta gagatagaat agcaactaag aggaaactaa
    26821 actgtgaatg gggtattttg gattcaagtg aaatatctat acttctaaat caagtaaaag
    26881 atgtgttttt taaaataaca tatccagacc ctgttttagg gcacatagaa actaaaactt
    26941 tttatgtagg agataggtct atgcctgttg cgttaaaaaa agataataat atattttggc
    27001 agagtctaaa aatgaatttt atagaaaagt aaggaggtat attcatggat ataaaaataa
    27061 gtgatagatt gctttatcaa aaggctttaa atgaggttgt aaaacttcaa aacgatttaa
    27121 tcatacaaaa agctattaat gatgaaaaag atacttatat tattgaacta caagaaaaat
    27181 tagctgagct tgaagaatgt gataataatg aaggaaacta gtcaagaata taaaaaagca
    27241 atattggaaa attcaaggat tataagttct aaaattataa taaatgatga aaaatatact
    27301 gatgaagata taatatctat aaatatagaa gaatctattt taaataatga gaagtttgaa
    27361 cttggtggag ggatagctac atcagtaaac atagaaataa ataactattc taataaattt
    27421 aaagactata aatttaaaaa taaatggttt gaactttatt tttatataga aatagcaata
    27481 aatgaatatc aatcaagaat agaagaaatt tattttggaa aatattatat atttgaaaca
    27541 gaactaagtg gaaaaataat aaaacttgaa tgttatgata cccttatatt aactgataaa
    27601 gcctataaac caaatatagg atttccagca acagtttatg atatagtcat agatatagca
    27661 aacattttaa acctaaagtt aagtgataag atagtaaagc gtagatttaa taatgatgac
    27721 ttacttatag aatataagcc aaattcagat gaagctacat ataggcaagt tttgatggac
    27781 tgtgcagtta ttgcagggtc ttttttaatt gttaaatatg gtgaaataga atttttagac
    27841 ttagtagaag caaatgtgca aattacaggt gagaattggt ttgatgtaac tataggtagt
    27901 gaatctaata aaataaattt tgttgatata aatggcgtag ttgctggaga cccatttgaa
    27961 aatggattac agttaagtat tttattactt gattataata aggaaaatga gataagagaa
    28021 gttgcacaaa gcattttaaa taaatacaag aattttgttt atactggttt tagtatggat
    28081 tggcaaggtg attttgcact tgatgtaggt gacaaattaa ttatctatga taaagacgat
    28141 atcccaaaga ctacatttat aagtgataat aaaataagtt acaatggtgg actgagttct
    28201 acaattgaag caaagataga taaagaggaa gttagaagtg catcaaggac tatacaaagg
    28261 cttgatagta atttgaaaaa gcttgagagt ggttttattc aaacaaatga aagtatagaa
    28321 ctttatgtaa aagaaattac agataaacaa gaaactttag agtctaagtt tgaaatattg
    28381 tctggtagta tagaagctat agtacaaagt acagttgatg aagcaatatc aaaaattgtt
    28441 attgatactg aaaaaatagt tatggaagta actaaaaaaa tagatggtca gtatatagta
    28501 tcaactatta atcagtcagc agaaaagata gagatgtctg caataaatat tgatttagaa
    28561 ggatatgtta ctttcaattc acttgaagat gagggagaaa ctagaataaa tggtagcaat
    28621 attataacag atactttatc tgtcgataag ttgaaatcaa gtacagataa tccaattatt
    28681 catctatttg taaatgatga acgaggcatt gattgctcta tagatgctac agctcaatat
    28741 gaagagggtg ttggggatgc attaagatat aagagagatt ctgaaaatta tctatgtatt
    28801 agagaaaatt ctttcagtct atatcaaagt ggttatccag agtatgaagt attcactctt
    28861 gggaacaatg caaattcttg ttttatagat actgtaaatg gaaaaatctc ttttgaaaaa
    28921 gataaattat attatgaaaa tgcaggagtt aaaaagaggg tattactaga tggtgattca
    28981 actggaggtg gtgattctga gggtgaagat agtggtggaa ctacaaaacc accaaatcct
    29041 gcaaaagaag ccaaattttt tattaaagaa ggactaggtg gttctagtaa cgaaagttta
    29101 acatttagtt cgtacgattt tgcttttata agaactgtag aaactgagca gggaacagtt
    29161 tatagagtta caggtattta ttctagcact agttttagtg aaataacttc agagttactt
    29221 gaattatcag catataaaac ggtaaaaatt atttttaata tgcaatatta tgctcgaagt
    29281 tctggtgtat attctatgac agttggcata ggatgtggac ctcaaaacaa ttctacttat
    29341 atgtatgaaa aaactttaga atttaatgat gtaacagata aagctactat acgatataac
    29401 gtgattttga cttgtccttt caacattcaa gatgctttta taaggttttt tgttagaaat
    29461 aaagaaaaaa tagatttaag tataattata gatattataa gttggtggat tgaataattt
    29521 ttatttagtt aaaggtaggt gagcaaaaaa tgagggataa aacttataca gttgatttga
    29581 atacgaaagt atattctgtt ccaatatata aacaatttga taatctaata cctttttcaa
    29641 taaaattgat tgaagatggc aaagaaatag atttatcagg atatacagct ttagcgtttt
    29701 ttcagaatga taaagtacta attcaaaaga attgtattat aaatgataat attgtaaaag
    29761 ctattttaga taacaatatt cttgcattac ctggattaat caaggtagaa tttcaattta
    29821 gaaaaaatca agagatagta actacttttc aaatgaaaat acaagtagag gaatcattag
    29881 acaaagaaaa tgcaatagaa tcaacacctc aatgggattt attaggtcaa gcaattattg
    29941 atattacaaa ttcaataaat gatataaatg aaactaaaga gaatttaata aatgatataa
    30001 atactaatat aagtacatta aacagtaaga ttgatagttc tgtagataca atgattcaag
    30061 atattaatgt tgttaaggag aatttagtag atgatatatc agagttaact acgaaagtag
    30121 atgaacgtgt agcactagag atatttgatg gagattataa tagcttaatt aataaaccaa
    30181 ctaaagtatc tgattttgaa aatgatgcag gatatataac aagttcagac atagatagtt
    30241 cacaaaatca tgttcataca aataaggcag ttttagatgg aattacacag gataaagtga
    30301 caagttggga ttctaaatca aatttcgatg ggaattacaa tagcttaaca aataagccaa
    30361 ctaaagtatc tgattttgaa aatgatgcag gatatataac aaattcagac atagacacat
    30421 cacaaaatca tgttcatagc aataaaattg tcttagatga aattacgcaa gataaagtgg
    30481 taagttggga tgctaaaaca aattttgatg gagactataa cagtttaata aataaaccaa
    30541 atttaacttc aaaggcagta actggattaa atttttgggt tggaacacaa gctgaatatg
    30601 attctgtaga tataaaagat gctacaacat tatacctaat aaaagaggaa taaacaaatg
    30661 tttgtattaa ataaaactag gatatcaaaa gttcgattaa gtgaagaaac aataaaacaa
    30721 atttttttag gtgatgaatt aattttttca aataagttgc ataaaaaaag ttttgaaata
    30781 ggaggaataa aattaagaaa tttaacatgt aacttagata tcaaaaacaa agataagaca
    30841 aatataaaat taaatgaaaa ttacttaaag tattctatta ataaaattaa tttaagatgt
    30901 ttagtagata gatacaatta taaaattgat tatcccataa gcaaagaatt aaatgaaaat
    30961 tatttaaagt attctattgg taaaattaat ctaaaaactt taatagatat atacaactat
    31021 aaaattgatt atcctataag taaaacattt atagaaaatt ataataaatt ctcaattggg
    31081 agaataaaaa tcaaataata tggagttgat agtgtggcgt taaaaggaag tgcaacaata
    31141 gaacttacag acagtcaagg aaacaaagaa gtatataagg aagacaatat aataactaat
    31201 gcagtacaag acttactaaa tataaactta aatggtcaag tgatgccatt taaatttttt
    31261 cctcttaaag atttttttag tggagtcttg ttgatggata gtaatataga agaacgacca
    31321 gatattacta caataccaag tggcgtagaa gttttggggc atgcaggctc agaaacaaat
    31381 acaactacaa ataccttaaa aggttcaata aatttaacag aaacaaaaga attaaataat
    31441 ggttataaat ttgtttggga tttttcaaat actcaaggaa acggaattat aaaaagtatt
    31501 tgtctaactc atttaaaagc aggtaatgat aatttgtata ataatatagt aactgatgtt
    31561 tctacttatg attcagataa atattggtca aatgatgtaa aatatattac atctatagat
    31621 tttgaaaatg gaattttata tgtatgtaaa aaaggttctt ctacaactga tataaccatc
    31681 tataagtatg ctcataattt tctaagcttt ggtataaatg atatttattc aaatattaaa
    31741 ttgatagaaa caaaagttat aagtggaaca acaataggag cgataaaaag cgagttaagt
    31801 ttttcagatg gtcgagatgg atatttatat ggtttttatg cacctagaaa agcttccgga
    31861 gatacaatct taaatataat aagaataagt aagagtgatt ttacatatac agaaaaaagt
    31921 attactctta cagatgttca actttatttg ccaaatgatt tttactatgt aaatgtttgt
    31981 cctatcaaag atggttttat atatttatta gattataaaa caaaaagtac tttttataag
    32041 atgaatctta cagatgaaac agacattaaa ttgttagaaa gtgataataa aaagcaattg
    32101 atatcatctg aaggaagtag ttttgcactt attggtgata ctttatactc aaaatatgta
    32161 actatattta atgataaggt gagagaaata tctaaaaatt taattggtga tgcttattgt
    32221 atccattcat ataagaatta tttaattaga ttttattcat attcagtaat aggctatttg
    32281 aatgggatat taacaacagt aaataattta tccacaccaa ttgaaaaaac tacagataaa
    32341 acaatgaaaa taacatatat aataacagag gcataaagta agactatata acatagtctt
    32401 tttttattat ctaagataac tttatataaa aggataaagg aaatgataga attaaaaaat
    32461 cagaaagtag ataaaattta tttaggtcaa agagatataa acaaaattca cataggcaat
    32521 aatttaattt attctaatag tatagagata aagcataatg agcgatatgg gctttacatg
    32581 acagctaata ataaaccaga accatttgag gtcacatcaa gtcaaaatgt ttggggagca
    32641 tatagagcat ttacagaaac tttaagtgat gatttaaact taactggttt aagtaaaaac
    32701 acaagtcaat gggttcaaat aaaattggat aaaaatataa agatatgggc tattaaaatg
    32761 cactttagaa caacaatatc aaatcaagat actgcacaag ttccatttaa attcaaactc
    32821 ttaggctcaa atgatgggtc aagttttact gaattacaca actgtgaaag ttgtaatcca
    32881 gatttgtttt gtaaatggaa ggatgacatt tcaaagtacg atttttctga tgctgatttt
    32941 atagaagtaa gtagtaacag tgagtatcaa tattatagag ttgaattttt taatactcaa
    33001 agcatatcaa aaggaaatgt aattaataca gaaggaactg aagttaaaat aacattattg
    33061 aatttatatc agttagaata ggaggtcact atggaacaac tagtaacaga attaagtagc
    33121 ttgggagcaa taggaatatt atgtgccctt ttattcaaaa atacaatgca agagaaaaaa
    33181 gaagatagag atatgtataa aaagacagtg gaaaacttta tcgagttatc tacacaacaa
    33241 caagaaatta ataaaaatgt attaatagaa atgggaataa tgaagataga tgtacaaaaa
    33301 ataaaagaaa atgtactaga tataaaggat atgttacaaa gataaaatag tttatagcta
    33361 gaatctcata gaatcattat aaatataatt agaaggcata aaaaagagaa tatttaattt
    33421 ataatcaaaa gatatataga aaaataataa tatctttaaa agatttttct tatttgatat
    33481 aattaaggtt atgtgtaata taagaaatta actaggagga atagacgtga gcaaaagaaa
    33541 acaagtaaca atacctatag agaaaataca agaacaagat aaatatat
//
LOCUS       DAEPXW010000039        32482 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.040, whole genome shotgun sequence.
ACCESSION   DAEPXW010000039 DAEPXW010000000
VERSION     DAEPXW010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32482
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.040"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(16..729)
                     /locus_tag="KRM55_001843"
     CDS             complement(16..729)
                     /locus_tag="KRM55_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBH1594089.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            1021..2685
                     /locus_tag="KRM55_001844"
     CDS             1021..2685
                     /locus_tag="KRM55_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBH1594090.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(2792..3691)
                     /locus_tag="KRM55_001845"
     CDS             complement(2792..3691)
                     /locus_tag="KRM55_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBH1594091.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(3718..4356)
                     /locus_tag="KRM55_001846"
     CDS             complement(3718..4356)
                     /locus_tag="KRM55_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH1594092.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(4693..5691)
                     /locus_tag="KRM55_001847"
     CDS             complement(4693..5691)
                     /locus_tag="KRM55_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBH1594093.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(5789..6364)
                     /locus_tag="KRM55_001848"
     CDS             complement(5789..6364)
                     /locus_tag="KRM55_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594094.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            6680..6943
                     /locus_tag="KRM55_001849"
     CDS             6680..6943
                     /locus_tag="KRM55_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594095.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(7380..7757)
                     /locus_tag="KRM55_001850"
     CDS             complement(7380..7757)
                     /locus_tag="KRM55_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1594096.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            8098..9210
                     /locus_tag="KRM55_001851"
     CDS             8098..9210
                     /locus_tag="KRM55_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1594097.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVYIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(9418..9894)
                     /locus_tag="KRM55_001852"
     CDS             complement(9418..9894)
                     /locus_tag="KRM55_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594098.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(10093..11718)
                     /locus_tag="KRM55_001853"
     CDS             complement(10093..11718)
                     /locus_tag="KRM55_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1594099.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALLNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(12056..13075)
                     /locus_tag="KRM55_001854"
     CDS             complement(12056..13075)
                     /locus_tag="KRM55_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBH1594100.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(13072..13641)
                     /gene="mocA"
                     /locus_tag="KRM55_001855"
     CDS             complement(13072..13641)
                     /gene="mocA"
                     /locus_tag="KRM55_001855"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBH1594101.1"
                     /translation="MINAVIMASGFARRMGVNKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            complement(13748..14470)
                     /gene="yqeC"
                     /locus_tag="KRM55_001856"
     CDS             complement(13748..14470)
                     /gene="yqeC"
                     /locus_tag="KRM55_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBH1594102.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRNKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            complement(14653..15930)
                     /locus_tag="KRM55_001857"
     CDS             complement(14653..15930)
                     /locus_tag="KRM55_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1594103.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(16069..18375)
                     /locus_tag="KRM55_001858"
     CDS             complement(16069..18375)
                     /locus_tag="KRM55_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1594104.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPVFDKY
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(18368..19162)
                     /locus_tag="KRM55_001859"
     CDS             complement(18368..19162)
                     /locus_tag="KRM55_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH1594105.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(19269..20627)
                     /locus_tag="KRM55_001860"
     CDS             complement(19269..20627)
                     /locus_tag="KRM55_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH1594106.1"
                     /translation="MKAKSTSKFELDGIPPLKEATPLGLQHLMAMVIGSCLPAILIAN
                     ASGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(21973..22938)
                     /locus_tag="KRM55_001861"
     CDS             complement(21973..22938)
                     /locus_tag="KRM55_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594107.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEITVMKEDMSEVKQEINVLKGNMSEVKQEMIVMKEDMSEVRQEINIMKEDMSEVRQ
                     EINTMKEDMSEVRQEMTVMKEDMSEVKQEINVLKEDMSEVRQEINIMKEDMSEVRQEM
                     TVMKEDTSEVKQEINVMKKDMSEVRQEITVMKEDVSEVKSEVNFMQNKINNINEDMNG
                     IKDEVSIANEKLYGIEIKIDSLECEDKSMKEIQIEQNNILGSLLHNSEINKATHDNIE
                     HNIAYIKGDTNSIKEDIAEIRRDLNLVELATSKNWSDIVKLKSVK"
     gene            complement(23168..24253)
                     /locus_tag="KRM55_001862"
     CDS             complement(23168..24253)
                     /locus_tag="KRM55_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH1594108.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(24289..25602)
                     /locus_tag="KRM55_001863"
     CDS             complement(24289..25602)
                     /locus_tag="KRM55_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1594109.1"
                     /translation="MIAIKSKYLISSADEIYANSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNSP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETILASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(25603..27894)
                     /locus_tag="KRM55_001864"
     CDS             complement(25603..27894)
                     /locus_tag="KRM55_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1594110.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(27884..28678)
                     /locus_tag="KRM55_001865"
     CDS             complement(27884..28678)
                     /locus_tag="KRM55_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH1594111.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(28717..29163)
                     /locus_tag="KRM55_001866"
     CDS             complement(28717..29163)
                     /locus_tag="KRM55_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH1594112.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(29235..30641)
                     /locus_tag="KRM55_001867"
     CDS             complement(29235..30641)
                     /locus_tag="KRM55_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1594113.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     IRGTIKNRMEGHKWNSLY"
     gene            complement(30659..32029)
                     /gene="hydA"
                     /locus_tag="KRM55_001868"
     CDS             complement(30659..32029)
                     /gene="hydA"
                     /locus_tag="KRM55_001868"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH1594114.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(32162..>32482)
                     /locus_tag="KRM55_001869"
     CDS             complement(32162..>32482)
                     /locus_tag="KRM55_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1594115.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKS
                     VYGK"
BASE COUNT        10412 a         5834 c         3410 g        12826 t
ORIGIN      
        1 aagttttcta tatttttaac caacagatgt tttcttcaaa ttaatcagat gatttagtat
       61 atcttgaacc tttccagagt cctttaaata tcctaatgcc ccatttattt gtgattttaa
      121 atctatttct acttccatat ccaaatcaac atttcctttt tttatagata tatttttaag
      181 tgttattggg taaagataac ttttttccaa agtaatctta tttccattaa cctcaaatgg
      241 aactttttta ttgtagttac ttaatatttt ttctagcatt ttatcactta gtttaaattt
      301 tccaattttc acattctcaa gacttacaac taagtttcca tcctttaaag taggtctcaa
      361 ttcaagttca tattgactat ttaccaaacc aaatacctta tatggtcctg ctacctttat
      421 tttaccattt ttcatttcaa caaaattatt ttcaagttca ttaattccat gcttctgcat
      481 caatgtatat attaaatttt taaactcttc ctctgaaaca gatatttttc caaccattct
      541 aagtggattt tttactacct ccatagaatt tatatatgag ccttttgata aatattcttc
      601 atctatgatt ttattatttt gtgaactaac atcatatctt tcttttggtg tcaagatata
      661 tacaacaatt cctgcaagta ctaaaacaat aacaattaaa cttaacaaaa tctttgcaac
      721 ctttcccata atcgtctcct ttacaaatct gtcatcagat ttaaaataaa tttagataac
      781 taacttcaca taatattctt aacaatatac atactataat acagtctttt aaaaattaat
      841 tcaaccaatc taatgttttg taaataaact gtaaaaacat gtttttagta taaaagttaa
      901 tattttgcat aatactctta attacacctt tatttttttc taatcttgga ttaaaattaa
      961 tattatgcaa tacagtgtag tgttctgtat tataatcaaa ttaaatagga ggtatagaat
     1021 atgtcaaatg aaacgaactc atctaacttt ataaagaata ttattataaa cgacttagaa
     1081 acaggaaaac atgacagtat cataactcgt tttccacctg agccaaacgg atatttacat
     1141 attggtcatg caaaaagtat atgtcttaat tttggattag ctaaggagtt taatggaaaa
     1201 gctaatttaa gatttgatga tacaaaccca ttaaaagagg atgttgaata tgtagagtcc
     1261 ataaaagaag atgtaaagtg gttaggattt gattggaacg agttaaattt tgcatctaac
     1321 tactttgatg aaatgtataa gagagcttta atactaataa aaaagggtaa agcttatgta
     1381 tgtgatttga cacaagagga aatgagagaa tatcgtggta ctctaactga accaggaaaa
     1441 gaaagtcctc atagaaacag aactattgaa gaaaaccttg atttatttga aagaatgaaa
     1501 aatggtgaat ttaaagatgg tgaaaaaaca ttaagagcca aaatagatat gtcttctcca
     1561 aatataaacc ttagagaccc aattatatat agaatatctc attcaacaca ccataataca
     1621 ggagataaat ggtgcatata tcctatgtat gcttttgctc atccaattga agatgcaatt
     1681 gaaggaataa ctcactctat atgtacttta gagtttgaag accaaagacc tctttatgat
     1741 tggtttgtta aagaatgtga gatggaaaat atacctagac aaatagaatt tgctagactt
     1801 aatataaata atactgtcat gagtaaaagg aaattaaaac aacttgtaga tgagggtatt
     1861 gttgatggtt gggatgaccc tcgtgttcct acaatatccg gaatcagacg taagggatat
     1921 actgcagaag cattgcgcaa tttctgtagt gaaatagggg tatcaaaagt taactctacg
     1981 gtagatagtc aaatgcttga ttatttccta agagaaaact tacaaccaaa ggctcctctt
     2041 actatgggag ttttaagacc tttaaaactt attataacta attacccaga agataagatt
     2101 gagatgcttg aaatagagaa taatgctaaa gatgaatctc aaggaaagag attagttcct
     2161 ttctctagag aattgtatat agaacaagat gattttatgg aagaacctgt taagaaatat
     2221 tttagatttt tcccaggaaa tgaagtccgt ttaaaaggtg cttattttgt aaaatgtact
     2281 gatgtaatta aggatgaaaa tggaaatgta gttgaaatac atggtactta tgaccctgaa
     2341 actaagagtg gctctggctt tacaggacgt aaggtaaaat ctacaataca ttgggttgat
     2401 gctaaatcag ctataccatg tgaatttaga ttatttgaac cattaattct tgatgatata
     2461 cctgaaaatg aaggtaaaca tttcttagaa caaataaatc ctaattcatt ggaaatatta
     2521 caaggttttg ttgaacctac acagataaaa gatgctaaac cttttgataa attccaattt
     2581 gttagaaatg gattctttag tatagataat aaatatacaa ctgatgaaaa atttgtattt
     2641 aatagaatag ttcctctaaa aagttctttt aaaccaggta aataatctta caatcaaaaa
     2701 atgaagactt aaaatataaa ttacttctac tataaataaa cttagttaga agtaattttt
     2761 tatttgagtc ttcatcattt actttaaatg attaactttt ttcactacag attcccatga
     2821 cttctattcc atcttttatg cattctatgt taagaggaaa atctggtcct ttttctccgt
     2881 caatatctgt tataagtgaa tcttcacatt ctatatgcac ctttttagtt ttaaagtata
     2941 gtatttcatt tccattatat tgatctaaat aatcacctct aagcacactt atcaaaactg
     3001 gtattgattt tggtattggc attcctttaa aaataattac atccaaatat ccatcatcta
     3061 tttcagcctt atatgctaga tttatatttc ctgctgtttt gccattaaaa atcaacataa
     3121 gatacatatc tccatcataa tacatttcct cagaagatac ttttatctta aatttcctca
     3181 tatacaatgc ttcttctatt ccctttatat aataagaaat tcttccaaat gaatttttta
     3241 agtctgtgtt tatcctttgt gatacatccg taaacatacc agcacttgca acatttataa
     3301 agtacttatt attgactttc cctatgtcta ttttctttgg ttttgaattt atgatttcat
     3361 ttatagcttc ttttatatca aatgaaattt gaagagcatt tgaaaaatca tttgcagttc
     3421 ctgtaggcaa aattccaatt ggaattttta tgtctaattc tttcattgca tttactacta
     3481 aatctacagt accatcacca ccagctatca atatgtgttc ataagaacta tcaacttcct
     3541 taaatgcatt ctttacaggt tctttaatag ttaatctata gggtatcaat aaataatttt
     3601 tttcttgata taattctatg atagtgtcta aatttgataa tatctttttt tcacctgaat
     3661 taggattgta tataagtttt acttttttca ttatttctcc ttactcattt tattctttta
     3721 gtatccaaaa tcttcattta aaaaaatcac atgtattctt tctggtgtta attgtctttt
     3781 tataagtgta taactacagc atattcttcc tggacttgaa cagtctatac atataccagt
     3841 agtcttacat ccagtatttg tacttaatct tttacaattg gctggagcag ctattgtttt
     3901 tgttcttttt atagcttcat ctacatcttt aactatttta tttactcctg ctataactat
     3961 tactttatca ggtccatata tcatagcagc aactctattc ccattcccat ctaaattgta
     4021 aagttctcca tcctctgtta tcgcattagt acttgtaaaa taagcatctg cagaaaatga
     4081 ctttctatat atttctttca tttcttctgg tttgatatct tttgcatatc tatcaagaaa
     4141 attatatttt tctcttataa aatcaatcac tcctgtttca aataaggtca tagaacctcc
     4201 acatcctact agagaacctg ctttaactat ttcttcaatt tttttaagaa gctcttcttt
     4261 gttacttact aaataccctt tcatattatt gttttccaaa gattttattg ttttttctat
     4321 tcttttttca ttaagccaat ttaaattttg atccatttta acttccccct tatttttaat
     4381 atgcacttaa ttatttataa actttatttt ctttataagt ttattttagt acatctaaaa
     4441 aaaaatacaa tataaaactt aaatagtttt acataatttt ttccaaaata acttactcaa
     4501 tcaaaaaagg aaagtagatg tactattcta ctttccctat attgtatgta gtatttattg
     4561 cctaaaatct atatattaat tatatgtttc atattatata atatcacagt taattaaaat
     4621 gtaatactat cttcttttta aacatataaa ttgtattatt aaatttaata tatccaactt
     4681 caataaatct tattaatttg atgaagaaga tgctatagct gcacttgttg ctgccattac
     4741 acatgcaatt tgaatagcaa caacaatatt taaaaatata ttattagtta tagagcctat
     4801 attattctca tttcgtatca aatctgcata aattgaagct acaatagcag aactaatcat
     4861 tactctatta ctttttccta aagaccaatt tccaaagcct ttttcttctt taagtttatt
     4921 tgaaacattt tttatctctt ctattatttc atcttctcta taatctaata atgaaattgc
     4981 tcctattatt ggatatccat aataattcat tttacaatca ttttctttaa atgctttttt
     5041 aagttcaata gtctttttac atttaagcat agttctatca tcactaaata aaagaatttg
     5101 ggataatgct tgtaaatcat ttcctttata aaaaccattt tcatttagaa attcataaca
     5161 tttttctatg tattctaaat cttcatctaa attttttgaa tgaattgcaa taagtgctat
     5221 attacaatag tcatcactag aagttagaaa tggatgtttt ttcctcatgt aatcatatat
     5281 tattttcatt tttgatatac atgtaagata atccattttc tctctatttt cataaactat
     5341 tgatgctgta agtggtaaat atgtatcgcc ccaaaacttt tcacttttaa gttctttgta
     5401 tatatctaaa atcatcttaa aactactttc tggatttgat tcaaacgaaa gtagtgttgc
     5461 catataaaac atattatatc ctctaaaatt agagaataat ccagtatttt ttttaataag
     5521 ctctattcgt tcttccacta atctaggact tattctcttg ttcttaaggg taaatgcaag
     5581 tgcacaacta tgttgtatca atcccatttg ccaagaacct ttaacttcat ttaatgcttt
     5641 gtaattttct attaataagt ttacttttcc atttataaac gattgttcca tattgccctc
     5701 ctagtaatat atctcattgt actaatagtt ttatatttat tatatatata ttaaatacta
     5761 caatcaatac atattacttc aaagaacatc attcttcaac aataatgtag ccttttttgt
     5821 aatgtcttcc catattattg actctatcat agtactctga ttcactttca ttactccatt
     5881 tgggcacaaa tacatctatt gcattagaat tactaaaata cttactagac cccctatcca
     5941 taacagtttt taattttcca tctacaataa tcttagttcc aaaacttaag tgattgtttg
     6001 ctacaaaacc atcttctaaa tcatctcctg tagcagttat cgctccatat ccattttctt
     6061 gattaagact tgtgtaataa ctaacttcaa aagttatagg tactaacttc tttattttaa
     6121 tacctaactg attttgtagt ttctcctttt gtactttcaa cttatactca tcactatttt
     6181 tataatcttc cataccttga ttatacttgg aattaaagct tttacctgac tttactatag
     6241 tatctatatt tactatagat tctttacaat gatctgcatc tatttttgtt tctccattta
     6301 ccaataatgg agttaaacat acactacata caacacatgt aatcaatgct tctttaagct
     6361 tcataaattc cccccttatt attttgatat attagcatat ttaatattat atgtctacat
     6421 ttagatttaa ataccacacc catttgcttt aagaagttgt cttatattta attcacctta
     6481 aacacttata aatcctctat cttagaatca tatagaataa agcttttatc tttaaatatt
     6541 ttttattaat cttttaaaat ctaaaactac tttatctaat tttctctttt ttagaattta
     6601 agaattaaaa ttctataatt ttaaaacata ttgaatttat ttttttgaga tgatataatt
     6661 ttcttaagag gtggttgata tgataaaaaa tacaaaacaa attacagtag aagttaatga
     6721 aattttatta caagaaatgt ctaagataac taatgacgaa aataatattt tgacagattt
     6781 gataaatgaa tcaattgtaa attatattct tgaaaacaaa aaacataata ttgaaaataa
     6841 agatttagaa gaagtgatta aattttacaa aaaagaaaat actgaaaaac ctaaaagtgc
     6901 agcaagagct atagctgaag caaaaactca tactctgtat taatcaaata aaaaagttcc
     6961 taaaaactag gaactttttt atattaataa ttattaatat atctcaatat ttatctcaaa
     7021 tctatcaata taagcatgtt taatacaatc tattgtatac ttatcttacc ctagaaataa
     7081 tcaaaacaaa aataaaatta tgccctttat atctaaaaca attaatttac atgattaata
     7141 tacaaaaatt ctgactttta aattcgtata caatatcaaa ctaaaataat attaatgaca
     7201 aacccaatat aaattaaatt caaacaggtt tgattttaca tcaaacttat tgtattaata
     7261 ttaaataaca agacaaaaat atttataaaa atcacaaatt ttacataaaa ctttatattt
     7321 gattcattta actaattatt gtaaaaacta tttattttat gataattaac tacaccaaat
     7381 tattcatctt ttttaatatc cttaacccat ttttcaacag agttcaattc ttcttcattt
     7441 accccctttt tgaacaagga tttcataaaa ctctcaatag aacttccatg catattatct
     7501 aaaaaagttt ttgtttcaaa atgtaaatac tcttcttctc caataagaac tgtataatgt
     7561 gtatgtctat caatttttct tgcacttaag aattgcttat ttactaatct tgataaaagt
     7621 gttagtgttg tagtttgctt ccaattatat agtttttcca tagcttcaat gacatctttt
     7681 gatgctactg taaaatctga actccaaata aatttcatga cttttaattc tgctggtggt
     7741 atcttagtaa tagtcatatg attttacact cctctcaaac ttctacataa ttaaatacta
     7801 tattaataga cttttcgagt caaaggtttt atttaaaata tctcatccaa atttattaat
     7861 acaaaaaatt tatattttta ttcaaaatta aacacacaat ctattaatat aaagataaat
     7921 atctattcta taagtataac agattatcaa attaaaattc taatatttga cataatatat
     7981 acatttttta aataaatata tacaatgtat taaaatgtat gcaactctat ttcaaaatta
     8041 ttttgtgata tatatatgtt ataataaatg tataaaattt tgattggtgg gttatatatg
     8101 aatgcattta ttagaaaaag aaataaaaac tatgttgttt acctggaatt tgaagatgaa
     8161 aagacaggta aaagaaaaca aaaaaatatg ggtacttttg ataaaaaaag ggaagcaagt
     8221 aaaagactaa atgaggtaaa agaaagctta tataatgatg gttttttagt accaagcgaa
     8281 attacagtgt cagaatttct attagatttt ctaaataaat atagtgaaaa tatatcttta
     8341 gctacatata ataattatgt tagtatttgt aagaattaca ttaatccatc tattggaaaa
     8401 tataaaatac aagacttaca tccggtttac atacaaaact acatagataa actatcttat
     8461 aaactaaatc ctcaatcaat taagattcat ataaatatat tgaaacttgc aataaaaaga
     8521 gcttatagac tcaaattaat aaaagaaaat gttatggata gtatagaggc tccaagatat
     8581 aaaaaattta aaaatgagat ttatgataga gaacaaatga taaaattatt agatttagca
     8641 aaaaatacag aaatggaatt acctattaat ttggctattg gattaggtct tagaatttca
     8701 gaagttttag gtctaacttg ggataatatt gattttgaag aaaatacaat aacagtaaat
     8761 aagataactt cccgaattaa tggttctgtt attctcaaag agccaaagac agaaagctct
     8821 gttagaaaaa tatcttctcc caaagaatta atgtctttat taaaagaata taaaataaaa
     8881 cagaataaaa atttattaaa atcttccatt agaaataata ataatttgtt atttttcaat
     8941 aagaaatgtg aacctattgc tgaagatgtt atgagtaaaa aatttaaaag atttttagaa
     9001 aagaatgaat tacctcatat tagattccat gatttaagac actcacatgt tactttactt
     9061 ataaattcta aagtacctat aaaggttata tccgagagag taggacactc aaatataagt
     9121 actactctaa gcgtttattc tcatgtactt aaagaaatgg ataaagaggc ttctgacaaa
     9181 atttctgaaa gtttatttaa tgctaattaa tattaattta tcttagcttt aaattagctt
     9241 agcttattga gatagattca ttaatattaa atgtatctat ctcaaattaa taactactta
     9301 aataatctgt tttattttaa tttatcgcct cagttattat acttttttac gaaaaattat
     9361 actttacaat aaaaaagata ttcccttata gaaaatatct ttttaaatac tatattatta
     9421 tatacttgct aacattggaa tatctaacat cttcttcatt acatcatcta ctttttttgc
     9481 tttatattca ttgtatccaa ttaaatatcc tttttcatat gaacttttta aaatctcttt
     9541 ttcatataaa ttatcagatt tggcttctgt gacacttaaa ttataaagcc ctttacaccc
     9601 atcttcataa cctttattat accctttttc tgcaaaatag tttttatgat ttttttcgtt
     9661 atgtactgaa gatattgtta ctccagaatt ttcttttgta ctagcataag gacaaaaacc
     9721 tttattgtgt tgatgtgctg aatgtcctcc acaataataa cgtgttaact ctgatttatt
     9781 tttattatga tgacctcctg atgaattatg ccctcctgag tgagcatatg aaaaattccc
     9841 tacactaatc atagctaaac taattactac agctactaac cttttcttaa ccataatcta
     9901 ttccccccaa aatgttatat atttttatta tatcatctac tatattatat ttaaattctt
     9961 aatatacaaa atattactct attctgctaa taaacatgtt taaacaacat aaaaaacctc
    10021 ctaatatttg attaaaaatt tacacactca tgcatagcat gtctcaaata ttaaaaggtt
    10081 ttatactaat aattatttat cttttccata cattttagct aattggtctt gtatctcttt
    10141 actttctaaa tactcatcaa agtccatttt tctatccatt attccatttg gagttatctc
    10201 tataattcta tttgctatag tagatataaa ttcatggtca tgagaagtaa ataaaagcac
    10261 tcctgggaac ttttcaagtc ctttatttac agaagttata ctttctaggt ctaagtggtt
    10321 ggtagggtca tctaatacaa gtacatttgc atttgaaagc attagcttac taagcataca
    10381 tctaaccttt tctcctccag atataacttg agcttctttt aatgcttctt cacctgagaa
    10441 taacattcta cctaaaaatc ctcttataaa actttcactt ttttcttcag agaactgtct
    10501 aagccagtca accaaagaat attctactcc gtcaaaaaac ttattatgat tttttggaag
    10561 ataatcttga gaagtagtta ctccccattt atactctcca ctgtctggtt caagttctcc
    10621 cataactatg tttaaaagtg cagtagtagc tatttcatct cccataaata ctactttatc
    10681 atctctatcc aatctaaatg acacattatc aagaacctta accccatcta tagttttagt
    10741 taaattgtgt acttctaaaa cttcattccc aatttctctt gcaggtgtaa atcctacata
    10801 tggatatctt cttcttgatg gttgtatatc ttcaacttct aatttctcta actgtttctt
    10861 tcttgatgtt gcttgtttag cctttgaagc attagaacta aatctagcta taaattcctt
    10921 taattgagct atcttttctt cagtcttttt attttggtcc ttagccaatt gtaaagccaa
    10981 ttgacttgac tcataccaga aatcatagtt tccaacgtac atttgtattt taccaaaatc
    11041 tacgtcaact atattagtac atatttgatt taggaaatgt ctatcatgtg atactattat
    11101 aactatagat tcttctaaat ccattataaa attatttaac cagtttattg atttaaaatc
    11161 taagtggttt gtaggttcgt ccattaatag tatttcaggc ttaccaaaaa gtgattgtgc
    11221 taacaatacc ttaacctttt ccccaccaac tagttccttc atttgtttgt aatgcatatc
    11281 tttcgttatg ccaagaccca taagtatttt ctcagcatta gtttctgcat cccatccgtc
    11341 aagctctgca aactcacctt caagttcggc agcttttatc ccatcttctt cattaaagtc
    11401 ttccttcata tacaatgcat ctttttcttt cattatgttc caaagtctct catgacctct
    11461 tataacaaca tttaaaacag tttcttcttc atattcaaag tggtcctgtt ttaaaactga
    11521 cattctttct ttatcagtta tagatatact acctgtatta ggctctattt ctcctgataa
    11581 tatttttaaa aaagtagatt ttcccgcacc attagctcct attattccat agcaattacc
    11641 tttagtgaat tttaagttaa catctttaaa tagttcctta tcaccaaatc taagtccaac
    11701 acctgtaact tgtaacatta atatattttc ctttcttttt gctcataatt tattttatca
    11761 taaaactttg ataacatttt tattatatat tatcacgtaa atagtatatt ttttatacta
    11821 aatttgtgaa atatttatta aaataatact aaaaattgta aatttataaa aattaacaat
    11881 ctcttatatt atacttataa agaaatcaaa ttgcaacttt attcattctt ttacacattg
    11941 aaaataagtt attataattt ctaaataaat atgctttttt taaaacatca ttctagctgt
    12001 tttgtttcat atttaaaaag agtacttaat ttgtaaatac tcttttttaa taactttata
    12061 ttttagcaaa attacatgca ggataagtac atacatcaca gttcatacaa aggccaccat
    12121 gaccatatct agctatatca tacttatcaa gcttttcatc aattaaaacc ctagataaaa
    12181 ctatatcaaa tactgtagtt ttgtgataca ttgcgcatcc tggtataccc ataattggaa
    12241 cttctccgta ataagcaagt aaaaacatag ctcctggtaa tattggtgaa ccatatgtca
    12301 ctaaatcagc tccagtttct tttatagctg ttggcgtaac atcatctggg tctacactca
    12361 tcccaccagt acaacagata agttctgctc cttgacttat aaattctttt attgcactct
    12421 ttataatttc tttatcatct gggcatatag tctgtcctat aacttcacaa ccaaagcctt
    12481 ttactttttc ttctattact ggtccaaatt tatcaacaat tctgctataa aacacttcat
    12541 ttcctgtagt aacaattcct actttcttag gtttaaaagg tactacattt actatttttc
    12601 tattaccaac tacttttttt gcatcttcta attttttctc atctataact aaaggtatca
    12661 ctcttgttcc agctactttt aaacctttat ttactataaa attattatga agagtagcca
    12721 tcattatttc tccaacacaa ttcaaatcaa aaagtgcatc aacatctatc tttaatagac
    12781 catcacatgc tgctataaaa tctattttcc cttcttttat ttcactaaaa tctaaatttt
    12841 ctccagcagt tagttctttt aaaaacaatg cgccttcatt ttcatgaacc attccttctg
    12901 acttttccca tacatacaaa ttatctttac caagagataa taacactgga atatcttctt
    12961 cttttactat gtgacccttt ttaaattttc ttcctttaaa ttctccaggt attatttgag
    13021 ttatgtcgtg acataaaact tgtccaacag catctatagt ttttattagc ttcataattt
    13081 acccccaatt ctctcatagt ccatttttgt atcgatatca aataacattt ctttaggaac
    13141 ttctacatac tttatttttg atgaattttt taaaatggtt ttaccttttt catcttcttt
    13201 aagtgccaac aattcttctt tcttgctata tgggaatatg actggatttc cacacatatc
    13261 tttgtatctt ggaattacta taaaatctct atctaattta aaagtattta taattttatc
    13321 tatatataag ttatcaataa atggctggtc tcctacaaag aacatataac catcacattt
    13381 tgagctattt aaaactccta attttataga ttcactttga cctatatttg catttttatt
    13441 atctatatat tcaaaaccat atttattaca caataacaaa acctcttcat attgacttac
    13501 tactacaact tgatgaaaat caatcttgct aacttctcta aatacatgtt ctattataga
    13561 acagccttta taatttaata aaagtttatt tactcccatt cttctggcaa agcctgatgc
    13621 cattatcact gcatttatca tatatatcat ccttggtatt tataatatat tgatagttct
    13681 atgattttta taatatctct attgatatta tctatatata taatatcata taaactattt
    13741 taatacttca atatcttaca caaaattttt gttttacact tccataaaat atctctattt
    13801 cactttcata ttctttaata ttttctatta attttatagc taaattttta tatttttcat
    13861 tttcaacttt attaataaat aatactcttt ttccagaata atttttaaat aatccatttg
    13921 gatttaatac tatatttttt aagttttcaa tacttactgt agaactacta ttaatactac
    13981 ttgtatctaa atttgctatt tttttaaata tttctactct atgtatattc tcttcattaa
    14041 tattcattcc aaatgatgtt atatctaata tccctatggt ttttgtagtt ttatgatata
    14101 ctactggttc tttagcattc caacctttaa gtttttttct ctttgagcca tctccctcta
    14161 ttaaaactaa atcaaattgg tctacaattt catccaaaat agaggaatca atacttacta
    14221 atttattttc attatttata taactgccac agactgttat tccatgacaa atagatggaa
    14281 taacagttcc atctattgta ataattatat tgtcataatc gtttggtaca tatattttag
    14341 ttgttgttgt aagaagaact ttcaatttat ttctataaaa atttgcaaaa tagtttataa
    14401 acgaagtttt tcctcctgct ccaactacag ttattatttc attcttttct attatatttg
    14461 atagttccac actttcacct cttataacca gttttctaat ctcttaatta ttatagttag
    14521 acctttttag taaaagtgat ttttgaaatt ccataaactc gaaagtaaat agattctgtt
    14581 gtaaacaaca aggcggatcc aattcgccgc taagctgtaa gcttacgcta tcagtttatc
    14641 ttttaaatat aattaagata ttcttactct ctgtggttgc tttaatattt gaggattatt
    14701 ctgtaaatta gataaattaa ctacttgtga tttttttagt atattaagac tcgcatttac
    14761 atctgcattt ataatgattc caacactgga tttgtactgt ccacgcgtta ttctttcccc
    14821 tttaaagtca tattttttaa cattgtccac attgatatca ggtagaaaat catcagcaaa
    14881 aaaatctgat ttactagtat agctttcttc ttgcctaata aaattgatat tttttatttt
    14941 acacagatat tctaattttc cttttatctc tccaaatggg attcttataa aatttctata
    15001 tatttttctc tccatattat cacttttttc taacttagca ttatatccta caattaaatt
    15061 tccaatatta ttttttacac aataatcaat tatataaaaa caggttttat ttacatagtc
    15121 tttaacttga ttatttctct tattccaaac tttaaattgt tttcttgtta ttgcagttat
    15181 attctttttt aattttaagg cttctatttt atcattctgt ttgtttgccc actgattcac
    15241 agattttagc ctttttccat ctatgataaa actatcacct aaattggtaa cacatgtaca
    15301 taaattttct aaacccaagt ctatagctag tgcatttttt tgatttgaaa cttcctctga
    15361 ttttggtatt tcataacaat actgaatttc aaagaaccta gctttatgtt taggtattat
    15421 tcttatttct ttaatttttt tctctagtat attttgtgga acttttatac ttactttccc
    15481 atatagtttt ttaaatgctg gagacatagg tacatttaaa atcccatctt ctttgattct
    15541 tatttgacct attattatgc taaaaaaccc ttctttatct aaatatttag gtgattttat
    15601 ccctctaaag tcatattttc cttctttggc taatttaatt aacccaaaaa atgacctaaa
    15661 cgaactgtct acttctttta atatttgttg cgctatatta ctattgagaa gcttatagtt
    15721 ctcattttct ttgcatacat gataattagc ttcatagtta agatgttctc cttgattgaa
    15781 ataatgctgt cttacattat atgtaccaac attatataag ttcttagcta agaagcacat
    15841 ctctcgtaga gcttgatatt cttttttagt taagtttttt aattgttgtc tctgagttcc
    15901 atagtgtata ttttttattc tgtttgacat gaactcacct cctttagaat atactctact
    15961 agacattata tacggtattt ttacaaaaca ccatatataa tgtccattta attactttat
    16021 tttacaaaat aatttaaatt tacttgcttt tatacacatt attatttatt ataattgttt
    16081 attattattt ttcataccca tataaacttt ttcaaaagtc ataggaagct ctcttaaacg
    16141 aactcctgta gcattaaata ttgcatttgc tatagctggt gctggtgtat gtataactat
    16201 ttctcctaat gatttagcac cataaggacc tcctgggtcg aaattctcag caaaatctac
    16261 caatatattt ccaacttctt tttttgtagg aactttatac tgtaggaaac tatctgttaa
    16321 taatctccca tatttatcaa atacagggtc ttcatacatt gcaaacccta tacccatcat
    16381 cacaccacct tctacttgta ttctagctaa agttggattt ataactgttc cacaatcagg
    16441 tacacatgca aaatttatga ctttatattc gcctgtattt ttatctaatt ctatctctgc
    16501 aaatcctgct ataaatggtt ttattttttt caacatgcca aaagattctg ttgcttccaa
    16561 aactactggt acatcatcac tagcaaatcc tattcctcca acagattctc tacccaattc
    16621 ctctaataga acaaacttgc tattatcatt tttaacaaaa accctgtctt ttcccaactc
    16681 taaatcttct tttttaaatc ctagctttga ctctgcaact gaaagtaata tatcttttaa
    16741 tttatttgct gtctttattg ttgcatttcc tgtaaccgtt gttgtacaag aagcaaatgc
    16801 tcctgtatca tagggacata aatctgaatc acctgtataa atagaaattc tatctacagt
    16861 agtatttaaa gcttccgcag caatttgagc ttgaattgta tcagcccctt gacctaagtc
    16921 agcaagacca gataatagtt tatatgtgcc atcttcatcc attcttatag tgactgttgc
    16981 catatctaca cgcggtatac cagaaccatg atttgctact gccataccta ctgctcttac
    17041 tttgttgttt cctatatctt tacatggata tttatcatcc caattaatta atttctttcc
    17101 cttttctata cattgtctca gctcacaact taatatttcg tcttcagctg cttttccatt
    17161 ggtataccta tctattatat ttttaattct aaattcaagt gggtccattc caatcttatg
    17221 tgccaattca tcaatagcac tatctattgc aaatattccc tgtgtagcac cataccctct
    17281 aagtgctcct gctggtaacc tattagtata tactgttcta gcattaaatc taacagcatc
    17341 aatatcatta tatattggta aggtattgtg tccagattcg gaagaaacag agacaccatt
    17401 cccaccataa gcacctgtat tgtttaatga ctttagctct attgctttta aatttccttc
    17461 tttatctgca ccaactttaa catcaaaaaa catttcatgt ctactattag aacctacaaa
    17521 agtttcactt cttgtaaata caaattttgc tggtctacca gttttcatag taacaaatgc
    17581 agtaaatata tctgttgctg ctatattctt tcctccaaat ccaccaccta ttctaggttt
    17641 aattactctt atttttgaag acggtatacc caatactttt ctaagtattc tctttacatt
    17701 gtgtggtgat tgtaatgatg aaactacaac aattctatca tttatatctt tatatgaata
    17761 tgacctatga gtttccatca tgcaatgcga ttgactttgg gttttgtatg aagattcaac
    17821 cacaaaatca ctttctttaa gcttagcttc aacatctcca aattcaaaaa attcttttga
    17881 tactatatta ttttttgcat ccaatccaaa agggtatggc tctactatgt ctttttctgg
    17941 atgtataaca acttcatttc cttctgcttc tcttgcatca aacacaggct ttaaaacctc
    18001 ataatctacc tttatcattt ttaaggcttt aagtgctgtt ttctcatctt cagcagccac
    18061 taaagctact tcatctccaa taaatctaac tgtatcttca agtaaaactc tatcataagg
    18121 tgatgcttct ggttctgttt gacctggaac acaatatctg acctgtggta catctttata
    18181 cgtataaata cccacaaccc ctggaatttt ttcggctttt gatgtatcta tattctttat
    18241 cttagcatga gcatgtggac ttctaagtag ttttaatgtc aaaacatctt tatgcataat
    18301 gaggtcttca gtatatagag gttttcctgt gacaattgct gtactatcta tctttcttat
    18361 ccccttatta atcattatac attccctcct caatagcatt atacatcctt ttaactaatg
    18421 cacttgccat atcctttctg tactctttac tagctctcat attacttcca taagtaagtt
    18481 ccttactagc aacaatagat gccttatcta tatctttttc tttatttaat atattactcg
    18541 cttcaagtgc taatctagct ttttgaggtc ttgccccaat tgctattttg taagtatcat
    18601 tttcttttag cattgctgaa tttaatacag aaaaatctcc tgtgcatttt cttattgagt
    18661 caaaaacagc tattgcatct ttttttggta gtattacttc gaccaatata tccctactta
    18721 attcactatc caaaaactca cttaactcta gtattccttt attgtataat ctcaccttcg
    18781 ctccaacaac caaaagtgct ggtattaagt cagaaaagcc atactttgaa aatacacttg
    18841 caccaattct agccccttgt ctaaattgaa caccaactat attagaaaca gcgcttgaaa
    18901 gtattccact acagtaattt tttatagttt tatcaatttc taaacttcta agtgaagtat
    18961 ctgcacctat caaaatattt ttttcatcct cttttatata atttagattt atatctttta
    19021 aatctatcgc tgttcctata tttttattac ttaattttat aaatccacat ccacctaaaa
    19081 taacattatt ttttttagaa attaaaattt tatatgcttc ttctaaactc tgtggaactg
    19141 aatattcctt tatagtaacc atcttatccc cccatcatta acttattaaa acacaaaagt
    19201 ttttaataaa tcttttattt atatttataa ttgtagtata tttaattcac atatattaaa
    19261 cctttacatt ataaactttt atttttatcc tcaaccttat cacttttatt tccaggaaat
    19321 tttaccatat ataaagcttg aattattatg gctaccattg ctcctgaaac tacacttgaa
    19381 tctgcaagta atgtctctat aaattttgga aatttttcaa gaacttgagg agctaccatg
    19441 aatccaatac cagaagccat agaaagacct aatatcatgc tattttcttg attaaatcca
    19501 tccatactaa caagtcttaa accagatgtt gtaagagttg aaaatataac gagtgttgct
    19561 cctccaacca cacagggagg aattgttctt attaaattag ctaataaagg cgatattcct
    19621 gccaaaaata atccaattcc tccaatagct agtacaaatt tacttacaac ctttgtattg
    19681 gaaacgattg cagaattttg tccaaacatc cccattggag ttgcagaaaa taatgcacct
    19741 attgtagaga gtactccatt tcctaaaaca gcagaagaaa gttcttcatc tgttacttgt
    19801 ctattaagcc ctcctaccgc agaaagtgta caagcaccca ttatatcagc tatctcaact
    19861 aaatatatta ttgaaaacat tacaacaact tcaagtctta tatctagccc aaaagcaagt
    19921 ggttttggaa gtgcaaccaa agtaaactcc tgaattgaag aaaaatttac tatacccaaa
    19981 attaatgata aaatgtatcc aaaaattatg ctaactaata ttgatgcatc tttaaataat
    20041 ccttttccat acttatttaa tcctaatatc ataagagata cagatattcc aactataaaa
    20101 ttaattggat tcccaaaagt ctcattgccc atacccccag ctaagttttt tatagctatt
    20161 ggaaaaagtc caagacccat acatgcaact attgttcctg atacagctgg agtaaatata
    20221 aatcgtattt ttttaagacc aaaaccaatt ataattatta ctataccagc tattatttga
    20281 gagccaaata atactggtag tccatactta cttgcaacag ataccccagc tcctataaac
    20341 atagctgtag ctcccattat aactggtatt cctcctccta atttaaaacc tttaaacaaa
    20401 ggtattggat ataattgtaa taaagttgat aatcctgcaa aaactaatgc ggcttgaatc
    20461 aataatgttg acatcttatg attaagtcca gatgcatttg caatcaatat cgctggtaaa
    20521 caactaccta ttaccattgc cattaagtgt tgtaacccta aaggtgttgc ttcctttagt
    20581 ggtggtattc cgtctaattc aaattttgat gtactttttg ctttcataat aaaaactccc
    20641 gttacataaa acttattgaa ttatataaat acttaaaaat ctaatatatt aaattaatga
    20701 tgttcataaa tatcaactat actccaacat atatttaagt ttttagtctt aaaaaacaga
    20761 tgcaataaat ttaattatta acaaatacac gtattcttta attttgtata cattatatac
    20821 catgctttac aaatataaga gtattatagc tatgaatttt taatttttta tagtaaattt
    20881 aattcaattt aaatctttca atcttaatca ttataagtta taagttttca taagtattta
    20941 catgtttcaa gttttaaaca tttacctata aacgctactt tatagatgtc acttcaaatc
    21001 cagtgacctc atactttcat atgagcgtag actatttctt catcttcagc attacctgct
    21061 aagagcaacc cgtttccact atcaatcgct tatagtgtac tctctctcga gatagtcgtt
    21121 tgaccttcct atttctaggc ttggcgacca aatgtccatt tttaagtact taggctctca
    21181 ccatatacca tcctcactat tgtttctggt tttcaccaca ttcataaaag tttctttcta
    21241 tcttttattg tagttgcaag gctttaggat ttactggttt taaagttgtg tcctacatag
    21301 atttctctat gtacggggcc aaaagtacaa tttatttaac atactttgct ttaccccctg
    21361 taaataatat tatttactct ttcactgttt ttgttattaa attaattaaa tatcaattaa
    21421 tctaagcata aaataattat ttaatttaaa ctcaaaatat ttatgaatat tttataatat
    21481 aattctcata agacagaaaa acttaataag ctatgtatct cagttgtacc aatgtactct
    21541 cctttactat atttgtatct gcaacataaa atatacaagt ttctatctat ttatagatat
    21601 atatatctat aagcaaaata gtaatattat ttttatagta aaaattttat tcatattact
    21661 atttataatt tttatagagc aattttagtg ccaatatttg catacatttg tatagtataa
    21721 aatttttatg ttctcattga taaaatttta cttatttcaa gcgttctatt agattttatc
    21781 atctaaattt taggttttat ttttataaat taattgtatt tacataaaaa aaaagaccta
    21841 aaacaaattt ttaacggtct tttctcaatt ttttattttc atttctaaaa tttataataa
    21901 atagtaagaa cactataaat tcttttatat aaaattctta gtttgtggat gataaattag
    21961 tgaattaaaa tactacttta ctgattttag tttgacaata tcactccaat ttttactagt
    22021 ggctaactct actaaattta agtctcttct tatttcagct atatcctctt ttatagaatt
    22081 agtgtcacct tttatatatg ctatgttatg ttctatatta tcatgagtag ctttatttat
    22141 ttcagaatta tgtaataaac ttcctaaaat attattctgt tctatctgta tctctttcat
    22201 tgatttatct tcacattcta gactatcaat cttaatttca attccatata atttttcatt
    22261 tgctatggat acctcgtcct taattccatt catatcttca ttaatgttat ttattttatt
    22321 ttgcataaag tttacttctg atttaacttc ggaaacatct tctttcatta cagttatttc
    22381 ttgtctcact tctgacatgt cttttttcat tacatttatc tcttgtttta cctctgatgt
    22441 atcttctttc attacggtca tttcttgtct tacttcggac atatcttctt tcattatatt
    22501 tatctcttgt cttacttcgg acatatcttc ttttaataca tttatctcct gttttacttc
    22561 cgacatatct tctttcatta cagtcatttc ttgtcttact tccgacatat cctctttcat
    22621 tgtatttatc tcttgtctta cctcggacat atcctctttc attatattta tctcttgtct
    22681 tacctcggac atatcttctt tcattacaat catttcctgt tttacttctg acatatttcc
    22741 ttttaataca tttatttcct gttttacttc cgacatatct tctttcatta cagttatttc
    22801 ttgttttact tccgacatat cttcttttaa cacatttatt tcttgtttta cttccgacat
    22861 atcatttttt atgctaacta catcttcatt tatagtatat aataactcta aaatcttctc
    22921 ttgcacttgc atcaccatcc ctattaatta ttataacatt ttacacaaat gctatacaat
    22981 gttaacatat atatcagaat tattaaaatt ttaattaaac aaaattgatt cactttatta
    23041 cttcaaaact aattaatatc taaaataact acaaataaac aaaaataagg tcaacaacaa
    23101 aaaaggctta tctctttgag atagcctttc ttatttttat ttaaaacttt gttttttata
    23161 aaataatcta tacattcagc tctgaacatg aaatttttct tccaagtgct tttggtttac
    23221 aaactgatat acaaagtcca caatatctac actcttcttc attcaattcc atcttatcat
    23281 tcaattttct cgcttgatat gcacaaactc tctcgcacat cttacattta gtacattttt
    23341 cttcatcata agtaaactca aagctaagtc tttcattaac atctcccata tgattatgta
    23401 ctataccaca agcattttct atagtattat atcctaatct attaagatta gattttaaat
    23461 catcatgtat tttagatatt acttgtgcgc cttttaaaat tactactgaa catataccaa
    23521 caaagtcagc acctgccata atcatttcta aggcatcatc tccacttaca catccaccta
    23581 agccaattat tggtatatta acttgttttt ttatttcata tattctctgt aaagttattg
    23641 gcttgatagt ttctccactt aaatatccta ttccatttcc acctaataaa ggttgccctg
    23701 tttctatgtc tattctaaat gctggtccta cagagtcaca agcagttatt gcatctgctc
    23761 ctgcttcttc taatttttta gcaaaatcgc ctatctcatc tatcatagga ggaagtttaa
    23821 ctattacagg tatatttact ctttcctttg catctttaag cattggtatc aaatctctat
    23881 agtcataaga tactaattca ataaagtcag ctcctgcatt tgcaactttc tctactaatt
    23941 cgctactttc ttcaattgta tgacctattg aagctataca gacagtccca tctcttttca
    24001 tttgtggtat ttcaaaatct atccattgct ctggctcaaa atctgtccat ttttcattat
    24061 ttaaaagagc attagctgta tttctaacca tatgtggtgc tggatttata gctctttctt
    24121 ttcttatagt cttagtcaca actgcccctg ctcctgcatc acttaatatc ttgcatccag
    24181 ctgcactata tgttaatggt cctgaaccta ttataagtgg tgattttaat tctttaccta
    24241 aaaaattata cattatctgc ttcccctttt catatatatt tatattcgtt aaaatttcca
    24301 aaattcacaa gcaacttctt tcatttcttt aacaatagct tttttatcta aatcaactaa
    24361 ctgtttttct tttaaaatat gtctaccatc tatgtataca tttgatataa attctttttt
    24421 accctgaact actatctggt caaatatatt atcaagagtc acaggagttt taaattcatc
    24481 ttccataact attatatcag ccttattacc aactgctatt ttaccagaat tttgaagtcc
    24541 taatacataa gcaccatgct ctgttgccat tctaaatact aaatttgctg gcattactga
    24601 tgcatcttct tcaactgatt tatgcattaa aaatgcacct ctcataactt caaaaaaatc
    24661 atttatatat ccatcagtac ccagtgccac ttttatgcct tttttaatca tttttggtac
    24721 tggagaaaaa cctccaccta cttcacagtt gctaagaggc atatgaacta cttttacacc
    24781 tttttctttt aatatatcta tttcttcatc atttactttt acacactgag atgctaatat
    24841 agtttcatcc aatatatcta aatcattata gtagtcaact gcttttttgc caaaatgttt
    24901 ttcagcatag tttggctcat atatactctc acataaatga aattgcattg gtgaatttaa
    24961 tttttttgca tcttctttag ctttcttaat aaatctatca gaacatgtga agcttgtatg
    25021 tgtacacatt attccattta ttaatttact attttctcta ctccacttta ttaaattaga
    25081 attttcatct aaacatctaa gtccattttc aaagcttatt ctttcacaac tttctaagga
    25141 taaaatcgct ttcatgccta tttcttctag tatttttcct tgctcaatta aagttccttc
    25201 ttctgtattt ggagcttcta gggtatcaca aaaagctacc acaccagatt ctataagttc
    25261 tattgctgat gctttagttg ttgccttcac ttctttcaat ccaattctat tttctataaa
    25321 tggccaccaa tagtcattta aaaaaccttc aaagtcagta aaatgtacat ttgccggtat
    25381 tcctctagaa agaactccat attgatgcat atgaccattg acgaatcctg gcattattat
    25441 agcatctgat ttatctatta tttcttcaat atttttatat tttatttcaa cttcttcatt
    25501 tggcaatata tcttttataa tgtcattttc tactacaaca gcagaatttg catatatttc
    25561 atcagcagaa gatattaagt atttactttt aatagcaatc atttatttac ctccctgatt
    25621 taattttttc atggccatat aaactttctc agaagttata ggaagttctc ttatacgaac
    25681 tcctgtggca ttgtatattg catttgctat tgctggtgca ggtgtatgaa taactatctc
    25741 tcctaaagat ttagctccat atggacctgt tggctcataa ttatctacaa aatcaacaat
    25801 tatgtttcct atatcttttt ttgttggaac tttgtattgt aatagattag aagtttgaag
    25861 ctttccatca gaaccatgtc tagggtcttc atacattgca agccctatac cttgagttac
    25921 accaccttca acttgtattc tagcaagtgc aggattcata actgtaccac aatctgtaga
    25981 acaagcataa tttattactt taaactcccc tgttgtttta tctaactcta tttcagcaaa
    26041 tcctgctaag aatggtttag cactctcttg tataccataa gattcagatg aatataaaac
    26101 ttcttgattt ccaccaccaa cagattcttt tcctaattca cttaacaaaa caaacttctc
    26161 tacatcttca ctataacaaa ctctgtcttc atatagtatt aaatcatcta ttggtaaatc
    26221 gagtttcttc tgtgctactt ttaatatctt ttgttttaaa ctttcagcag attttattgt
    26281 agcatttcca gttacataag tagtacaaga agcgtatgca ccagtatcat atggacacat
    26341 atctgtatct cctgtataaa cggaaattct atcaatagat gtattcaatg cttttgcagc
    26401 tatttgtgca agtattgtgt cagaaccagt tcctaagtct gaagacccag aaaacaactt
    26461 ataagttcca tcttcatcca tcctcatatt tactattgcc atgtctatgt tggctatacc
    26521 agaaccatga gttcccacag acattccaac agccctcacc ttattgttgc caatatccct
    26581 aacagggtac ttttcatccc atccaataag ttttttacct ctaattatac attcatcaag
    26641 tgcacaactt cttattggaa aattcattat tccgccttca gtttgttttt ttataatatt
    26701 ctttaacttt atttctgttg ggtccatatt aagtttatgc gctaattcat caattgcaca
    26761 atcaagtgca aatgtacctt gtgttgctcc atatcctctt aatgctcctc ctggaactaa
    26821 attagtatat acagttctcc catcaaattt tattgcaggt acattattat atgttggaag
    26881 tacattatga cctgattcag agcaaactga aggtccatta tcaccataag cgcctgtatt
    26941 gttcaatgct ttcatatcta tagcttttat gtttccttct ttatctgccc caatttttat
    27001 atcaaaaaac atctgatgtc tagtattagt cattgcaaaa gtttcttctc tagtataaat
    27061 tagttttgct ggtctttttg tcatccaagt tacaaatgat gcatatatct ctgttacagc
    27121 tatgtttttt ccaccaaaac ctccacctat tcttggtttt attactctca cttttgaaag
    27181 aggtattccc agtgctttag aaacctgtct tctcatatga taagctgatt ggtttgcaga
    27241 agttactact aatctgccat tcgtatctat atacgtataa gctctatgag tttccatcat
    27301 acaatgggct tgtgattgag tcatataaga atgttctact attacatcac tttctttaaa
    27361 ctctttttct acatcccctt tacccatttt ttctctcgat acaatatttt ttgtagcatc
    27421 taatccaaaa tcaaatggac aaaacaaatc atcttcttca tggattaaaa ttttatttcc
    27481 ttccgattct cttgcatcca atataggagt cattacttca tattcaactt ttataagttt
    27541 catagcttta atagcagccc tttcatcttc agcggctatt atagcaactt catctcctac
    27601 atatctaact acgtcttcaa gtattaattg gtcatgaggt gatgcttctg gatatgactc
    27661 tccaaccatt gaatatctat aatttggaac atctttgtaa gtgaatatgt ttactacacc
    27721 ttttaccttt aatgcatttt ttatatctat gttttttatc ttcgcaaaag catgtggact
    27781 tctaagaagc ttaattgtta aaacatcttt atgaaaaatt aaatcttctg tatatattgg
    27841 ttttccagta acaatggctt cactatctat ttttcttacc tctttattta ccatcacact
    27901 cacctccaat actattatac attctcacta ctaaggcttt tgccatatct tttctgtatt
    27961 ctttacttcc tcttatatta cttccaaatg aaagttcttc acttgatact tcaccagctt
    28021 tttctatatc attttctaaa cttaatattt cacttgcttt ataggcaatt tttgctcttc
    28081 ttggtctagc gcctatcgca attttataaa tacttccttc ttttaacatt gctccattta
    28141 atactgcaaa atcacctgta cattttctta tagaatcaaa tacacctata gcatcttttt
    28201 taggtaatat aacttctatt aatatatctt tttcaagctc actttctaaa aaatcagcta
    28261 agttcataac ccctttttta tataacttaa cctttgcatc taccactagt aatgaaggta
    28321 ttaaatctga aaatccatac ttagcaaata cgctagctcc tactctagct ccacttctaa
    28381 attgaactcc tactatatta gaaacagcgt ttgaaattac cccattacag taatttttaa
    28441 taaccttatt taattctaaa gttcttaaac ttgtgtctgc tccaattaat atgctatcat
    28501 cagtttcatt tatataatct aaagctaagt cttttaaatc tattgctgag ccaatatttt
    28561 tactacctag ttttaaaaat ccacatcctc caagtattat gttgtttttt cttgatatta
    28621 gcagttcata agcttcatct aaactttttg gaactacata ttcctttata gttatcatac
    28681 tctctcccca tatcaactta attttcactt aaaagtctaa gtgtttaaat atttatgtat
    28741 tgctcttaat tgacctttat atcctgtaca tctacaaagg ttaccattta cataatctat
    28801 aacttcttct tctgttggat tttgaagctc tcttttcatt gccaaaacca tcattataaa
    28861 tccaggagca caaaatccac actggtcagc cccttcgtct gcaagaaaat ctccaaactt
    28921 ctttgcttca tccaagacac cctcaagtgt tgtaatatgc tgaccttcta ctctagcagt
    28981 aagataatta catgaaagca cggccttgtc atttaccatc actgtacata acccacatga
    29041 gcctgtatca cacccttttt taacacttac atatccattt tctcttaatg tatctgctaa
    29101 aaaatcatct ggtcttatac ttaattcttt ttctttatta tttatggtac atttgataat
    29161 caaataaatc acctcaaaac tcatattttt aagctaaagt tttactatac ttttttatga
    29221 ataaattaca tttattaata aaggctattc catttatgac cttccattct attttttata
    29281 gttcctctta tacaaagtct ctcagctgta tcttgagcat cttttaatgc tttctcttca
    29341 ttagctgtca atatttttga atcttccatt attatatttc catctactat aacactctct
    29401 atatttttca tactagaaga atatactaat gtagataccg gattatgcat aggtatcgct
    29461 tttggtgaaa gcattggatt aaatattagt aagtctgctt ttttacctat ctccaatgaa
    29521 cctatctcat cttccattcc aatagctctt gctccatcta tagttgccaa ctcaagaact
    29581 ttttctgctg acattgctaa tgggtcacac ttattaactt tatgttgaag tgctgttaat
    29641 ttcataagtt caagcatatc ttgagagtta ttactagcgg ctccatctac tcctaaacta
    29701 actgttattc cttttttaag catttctggc actggtgcaa cacctgaaga taagtacata
    29761 ttacttgctg tattatgaga cactttcata tcgtattttt tagtaagttc catatctttt
    29821 tcagttagat acacacaatg taccataagc acatttggtc caagtattcc taatttttct
    29881 aaaacatcta tgtcatattg cccatgcaat tcttttgctg cttctctatc aaaaggagtc
    29941 tctgatatat gtactgtaaa taaagcatca tcatattctt ttactactct ccatagcatt
    30001 tcaagcattt cttgagaatt tgaccatatt gctgcaggag ctactcctat tttgattctt
    30061 ccattttctg tattatggtg tttttcaaac aatcttctta catctttttc aaccgtttct
    30121 acatcttgca ttattccagg atgaactcca aattgagctc ctgtattcat acatcctctt
    30181 ccaagtattc ctcttattcc taattcttta taagcatcta ttattccatc acaaagacct
    30241 ggcttactat gaggatacat gtagtcaacc attgttgtta taccacttct aagtccttca
    30301 atacatccaa gcattgcagc atcataagta tcttttggct ctaaatagtt agctgctgga
    30361 aatgtcatag tttctaacca gtctttaagt accatatcat ctcccaatcc ttttaataaa
    30421 gtttggaata aatgattatg tgtatttata aaacctggga ataaaacttt acctttagca
    30481 tctataattt ttttaacatc agtatattta ctttctatct ctttagaatt tccaatatca
    30541 gcaatcttgt tatcttttac tactaatgcc ccatcaaaaa taacttctct ctctttattc
    30601 acagttacta ttatggcatt cttaataagt atatccatca ttcttatttc cccccgcatt
    30661 atttagtaat ttttctttta atatattgac ctgttggatg ttctttaaca ttacaacttt
    30721 gtactacatg atttcctctc aaaaatacat cttcaacttt acatttaacc ttaaatcctt
    30781 catatggagt ataatctaca ttttgttttt gagttttata actaattgtt tcttctttat
    30841 tgatatttaa aatgactata tctgcatcac ttcctacagc tatctcacct tttttaggat
    30901 acattccaaa tatttttgca gcattcgtag aagtaacttc cacaaactta tttacactta
    30961 ttctattttc taagactcca tatgtatata aaagtgctaa cctatgttca acaccaggtg
    31021 ctccatttgg tatcttacta aaatcatcaa ttcccaagtc tttttgcccc ttaaaattaa
    31081 atgaacagtg atctgtgcca actgtttgaa tatctccact agacaatcct tcccaaaggt
    31141 aatttatgtc ttcttttttt cttaaaggag gagacattac atacttagca ccctcaaatt
    31201 tatccttatt atataaattg tcttctaata atagatactg tgggcatgtt tctactatca
    31261 tatctatgtt tttttctcta gccattttta cagtttcaag tgactcccta caacttaagt
    31321 ggactacata ggattttgaa ttagataatt tagttatatc agcaagtctt gaaacagact
    31381 ctttctcaac tatgttaggt cttgtaagtg gatgatattt tggctccaaa ttaccatttt
    31441 gtatattttc ttctatcaat acatctagta aatccccatt ttcacaatga aatccaacta
    31501 tacaacctaa atcccttgct ttctttaaaa ccctgtatat tgttccatca tctactttca
    31561 tgccatcata tgccatatac atcttaaaag atactatccc atccgaaata agtttttcca
    31621 tatgattaaa tgtatcttta tttaaacatg taattgtcat atgaaaacca taatcacaat
    31681 aacaatttcc acttgctttt ttatgatatg cttctacacc ttgcagtagg ttttccccct
    31741 cattggcttc tgcaaaatct agtattgtag tagttcctcc agctatagct gctcttgttc
    31801 ctgtttcaaa attatctgca gttgtaatag aacctgcatt catatcaaaa tgagtatgtg
    31861 tgtctattcc accaggaatt acaattttac ctgtagcatc aataacctta tcaccattta
    31921 tttctaagtt atttcctatt tcaactatct tttcatcttc tatccttaaa tcacttatat
    31981 aagtcttatc agaggtaatt atagttccac ctcttagtat tgttcccata tatacctcct
    32041 aacttttaag ctttaaagta ttttctaagt attgtaaaac tttatttaaa attgtatttt
    32101 ctaaaggtgc tatattcagc acctctagac tatatttaaa taatttattg tgaactaaat
    32161 attattttcc gtatacagat tttaatattc catagtaacc ttctgttcct ataaataact
    32221 gttcttgctc tatatactca tctattgtgt gagcaagatt ttccttagaa ggaccaaatc
    32281 ctatagtttt tattccagct tcacctgcat agtgacttcc attcgtacag aatgagtatt
    32341 gagttatttc tgaatctatt ccagcttctt ttaatccctt atatgctgct tgaacaaatt
    32401 catcttcttc gtcatataac caacctggga agaatctttc actttctata gtatttcctg
    32461 tatagcaatc agctttttca ac
//
LOCUS       DAEPXW010000040        31962 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.041, whole genome shotgun sequence.
ACCESSION   DAEPXW010000040 DAEPXW010000000
VERSION     DAEPXW010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31962
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.041"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(109..513)
                     /locus_tag="KRM55_001870"
     CDS             complement(109..513)
                     /locus_tag="KRM55_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBH1594116.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            complement(705..1892)
                     /locus_tag="KRM55_001871"
     CDS             complement(705..1892)
                     /locus_tag="KRM55_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBH1594117.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(1924..2349)
                     /locus_tag="KRM55_001872"
     CDS             complement(1924..2349)
                     /locus_tag="KRM55_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594118.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIC
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            2807..3556
                     /locus_tag="KRM55_001873"
     CDS             2807..3556
                     /locus_tag="KRM55_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH1594119.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(3722..4087)
                     /locus_tag="KRM55_001874"
     CDS             complement(3722..4087)
                     /locus_tag="KRM55_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1594120.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(4103..4879)
                     /locus_tag="KRM55_001875"
     CDS             complement(4103..4879)
                     /locus_tag="KRM55_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1594121.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(5326..6753)
                     /gene="ascB"
                     /locus_tag="KRM55_001876"
     CDS             complement(5326..6753)
                     /gene="ascB"
                     /locus_tag="KRM55_001876"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1594122.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(6814..8742)
                     /locus_tag="KRM55_001877"
     CDS             complement(6814..8742)
                     /locus_tag="KRM55_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1594123.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPDLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVYAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(8887..9729)
                     /locus_tag="KRM55_001878"
     CDS             complement(8887..9729)
                     /locus_tag="KRM55_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1594124.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            complement(10076..11446)
                     /locus_tag="KRM55_001879"
     CDS             complement(10076..11446)
                     /locus_tag="KRM55_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1594125.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYVASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SVINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            complement(11485..12156)
                     /gene="pgmB"
                     /locus_tag="KRM55_001880"
     CDS             complement(11485..12156)
                     /gene="pgmB"
                     /locus_tag="KRM55_001880"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH1594126.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNCNTLLQAWSK
                     KINLD"
     gene            complement(12158..14548)
                     /locus_tag="KRM55_001881"
     CDS             complement(12158..14548)
                     /locus_tag="KRM55_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH1594127.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDYFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSCGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPTGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(14574..16022)
                     /locus_tag="KRM55_001882"
     CDS             complement(14574..16022)
                     /locus_tag="KRM55_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH1594128.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERYNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(16414..17313)
                     /locus_tag="KRM55_001883"
     CDS             complement(16414..17313)
                     /locus_tag="KRM55_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1594129.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGVSQNELSS"
     gene            complement(17413..17862)
                     /locus_tag="KRM55_001884"
     CDS             complement(17413..17862)
                     /locus_tag="KRM55_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1594130.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            complement(17852..19759)
                     /locus_tag="KRM55_001885"
     CDS             complement(17852..19759)
                     /locus_tag="KRM55_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1594131.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGIYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNVNNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(20027..21922)
                     /locus_tag="KRM55_001886"
     CDS             complement(20027..21922)
                     /locus_tag="KRM55_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1594132.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVVTALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(21958..22836)
                     /locus_tag="KRM55_001887"
     CDS             complement(21958..22836)
                     /locus_tag="KRM55_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBH1594133.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(23379..23549)
                     /locus_tag="KRM55_001888"
     CDS             complement(23379..23549)
                     /locus_tag="KRM55_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594134.1"
                     /translation="MSALLYGVCNKPILISIVTNMQEFKIGVSMNYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            complement(23946..24158)
                     /locus_tag="KRM55_001889"
     CDS             complement(23946..24158)
                     /locus_tag="KRM55_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594135.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAVDIAKVFDTTVENLFEFIEEE"
     gene            complement(24159..24575)
                     /locus_tag="KRM55_001890"
     CDS             complement(24159..24575)
                     /locus_tag="KRM55_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594136.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLSTKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(24643..25056)
                     /locus_tag="KRM55_001891"
     CDS             complement(24643..25056)
                     /locus_tag="KRM55_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594137.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKYGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLIAVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            complement(25890..26519)
                     /locus_tag="KRM55_001892"
     CDS             complement(25890..26519)
                     /locus_tag="KRM55_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBH1594138.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(26598..27560)
                     /locus_tag="KRM55_001893"
     CDS             complement(26598..27560)
                     /locus_tag="KRM55_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH1594139.1"
                     /translation="MAKIDNMMSILWILNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(28240..31830)
                     /gene="cbpA"
                     /locus_tag="KRM55_001894"
     CDS             complement(28240..31830)
                     /gene="cbpA"
                     /locus_tag="KRM55_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HBH1594140.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAGGDANAGNAEGDANAGNAGGDANAGNAGGDANAGNAGNPEGDANAGNA
                     GGDANAGNAEEDANAGNAEGDANAGNAEEDSNAGNAEGDMNALVVEEATAEDPTSVGD
                     FKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFDGVN
                     IKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGMRAGKGTTLIIDDSVV
                     NRDIEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYYSAGIGG
                     GNTESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGDITINGGTITAKGAYH
                     GAGIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFGDGCVNP
                     GTNRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLGGAVAYG
                     DLEKKTKVFMNKISLKYLGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDDQGVLYLWF
                     SEQFKGSEVSVNLVVIDKITGGNIKPDDFYVKDIGSGSQFLKQYEEFTIDDTPPYLII
                     KRYDGLPFEEDVEKSFLDWILKDGGIPIITPKGEKLTDKKFMTISSQRLNEETMEPDT
                     NLGSDDLTKQVDAGKYQLSITSTQFSNVYPFNEAYWGHRAYYKAEIIPADTETSLVVE
                     ESKAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYINGKEYKDPVELKTHNK
                     GSESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLKLDVTNV
                     DVDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGNGDGIWK
                     PDKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPNLNKPDP
                     DNGGNSKPDPDNGGNSKPDPDNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNGGNSKP
                     DPDNGGNGKPDPDNGGNNKPDPDNGGNSKPDPDNGGNSKPDIDIDIDTDGDGKPNINI
                     DTDGDGKPDINIDTDGDGKPDVNIDIDGDGKPDVNIDIDGDGKPDINIDTDGNGKPDI
                     NIDTDESLDSNVGQNVQTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
BASE COUNT        10246 a         5689 c         3317 g        12710 t
ORIGIN      
        1 cactagtaag atatactaat atataaatac ttaaatttag ttttatttaa acgctctagt
       61 gatattttta aataaatttt aataaaaatc attctatttt gtcataaatc atttatctgg
      121 cttatattta agatatattg gtggatactt tacacttttt aattcctcat tacttcttaa
      181 aagtttatta ttattttcca tatcataaat ttgtaacatt actttattta catatagagc
      241 ataataatta tcactataaa aatattgata ctcatatcga gggtcatctt tgtaatacac
      301 tttgtatagt attccttcgt aacttgcctt cttggctttt tcttttgtaa tactttttat
      361 attatctttt gaaatatctt gttttaccat atacttatca atatatgttt cagcatcttt
      421 ccatggttta atgcagtttt tatatacaac aaaccctgtt acacttataa tacctataat
      481 taatactata aaaataactt tatatttttt catattgatc ctccttcatt tattatttaa
      541 aactcgatat aatgcactaa aaaaaggatg ttatcttttt tattaaaata taacatccct
      601 catatttagc atcaatatat atgccccaac tggtaggtta aaagacccca ctgtcagtac
      661 tttgattaaa ttacatgtat gtatatatat ttttaacaaa tctattatat gtcaacttgt
      721 ctactattac atataatctg taatattaca tctgctgctt tttttgagcc tcctgcatta
      781 taaaagcttt ttgatagttt agttgcattt tctttatatt cattgtcatt tataacttga
      841 aatactgctt ttttaatact ttctgactta tcctctttta acataattcc tgctcccaaa
      901 tgaacaactc tcttagctac cattctctgc tccgaatgtt gaggaaataa taccataggt
      961 actccataat ataaactttc attaacacta ttcatcccag aatgagtaac aaacacatca
     1021 gttttttgaa gtatagcaat ctgttcaaca ctatttttga cctcaaaatt atttggtata
     1081 tttcctaaac ttttaatatc agtacttcta ccaacagaca taatcacatc aacatcagaa
     1141 tctttaaatg cacttataca gtttttataa aagctaacat ttttattatt aattgtacca
     1201 agcgaaatat atattagctt tctttttctc tctttaggtt caataatcaa ctttgatact
     1261 gatggaccta caaatgaata cttactagag aaggtttcta ccattggttg aaattctttt
     1321 gatgtatata caatggtatc cgtatcatta tcattagaaa ctatagaaat aaaatttttt
     1381 acttcatacc cttttctttg taaaagcttt atttttttat taatgcgtct tacaccaaaa
     1441 atcatacgta taatttctat aaagttttgt ttcatcaact ttgctgtatg tttattaaat
     1501 gcaaaagttg ttgtagagca tacatatgga atattaagtt tttgtgcaaa taactttccc
     1561 caaaaactta atgaatctga tacaatgcaa tctggattaa aatctttaag ttctctacaa
     1621 actttttcat ctaaagaaat agtagtatct actatcatct caattaatcc aggaaaatcc
     1681 ttaccaattt ttttctcatc tccagggagt aattctggaa ggtatttatc acaacaaata
     1741 aattttgctc cagcaccttc aattttatct ttaaattcat taaaagaata atacaatacc
     1801 tcatttcctc tatccactaa ttcacgaact acttcaatag taggattagt atgaccatat
     1861 gcaggaatgc taaaaaatac tattttactc atatttcata cctcctttta taattttttt
     1921 aaatcattct tctttacgta ctactcccac atgacctata aaatttatca aatcacgttg
     1981 atgaacaatt cctaatcctc tttcctcatc tccaagtacc aataatttat ctcctgcatt
     2041 tatattaaat acttctcttg cttcttttgg aatgacaatc tgaccacgtt caccaactac
     2101 aactgctcca aagaaaaact ttcctttagg aggtactata atacctgttt tttcttctga
     2161 atgattaact aagtcatcta gtttgacatt gtacaatttt gcaagtttaa tgcaactaca
     2221 tatatcagga atagattctc cactttccca ttttgctatt gattgtctag aaacattaag
     2281 tttttcagct aattcttctt gtgtatactg gttgattttt cttagacttt ttaaattctc
     2341 attaatcata tttttcatac ctcctatgtt tataatattg gatttattat ttaaattcta
     2401 tcaactaatc ttaacattca tatatatatt tatatacttt tattatataa atttattatt
     2461 caggtaacat atttccttaa gttatcgtaa acaaaaaaac aagcacaaat ctactaactg
     2521 ttgttaaagt atttaagtta aggtcattta cattatcaaa tatttctaca cctttaaaat
     2581 aacctttata tttataatct ttcataagca aattattatc ccttctcata tacaagtcca
     2641 gttgatgtct tgttgctaaa tttaatggta atcaaattct ttaccaataa gtataaaaat
     2701 tactaatgtg ttataatttt cttaactact aaattttaca tacatttgaa tagaatatat
     2761 caataaatta ctataataaa taaaaaatag ttagggagat attattatga ttttatattt
     2821 tagcggaact ggtaatagcc gatatgtggc tcgtaaaatt gcacaagaat taaatgatga
     2881 actgatatca ctaaatcaac ttataaaaga ggaaaaaaca gatgaattaa tatcagcaga
     2941 taaaccattc atatttgtat gtcctactta tgcatggaga ttgccaatag tagttacgga
     3001 ttttataaaa gaaacaaaat ttctaggaag caacagagtt tactttgtaa tgacttgtgg
     3061 tggagataca gcaaaatcca taaactatat tcaaaaacta tgtaaataca aggaatggca
     3121 attaaaaggt atggcagaaa ttaaaatgcc agagaattat atagctttat tttctacaac
     3181 agacaaagaa acatcaaaac aaatgattaa agaagcagat aaacaaatat ataggattat
     3241 ttctgatata cgcaatgaaa atgaatttga aactattact cctagtggct taggaggtac
     3301 aattaaaagt ggtataataa atacagtttt ttataagaca attattagtg ccaaaggatt
     3361 tcattatact gataaatgca ttggctgtgg aaaatgtgta gagctatgtc ctttaaataa
     3421 tattaattta aaaaacaaaa aaccagtttg gaaaaataac tgtactcatt gtatggcatg
     3481 tatttgtggt tgccccactg aagctattga gtataaaaat aaaactcaaa acagagaaag
     3541 atactattta gaataatata ttcttaatat ttaaaccatt ataaaatgaa ctatacccat
     3601 tgttttatac agttttacat attttaaccg tctcctaaaa tgggtatagt tcaaaagata
     3661 gtgtctcaaa gtgaattttt tagttcctaa atcaatcttt ttgtattaaa tcaagtataa
     3721 tttaatcacc ttttcttata tcattttcac taatatgttg tattccaaca aatataagat
     3781 ttattagctc tgttagtgac ttccattgtg atttttttga atcaagataa taataatttt
     3841 tcgttccttc tctacgcaaa ttaacaatct ctgcttcttt taatatctta agatgatgag
     3901 atacagcagg acgagaaaga tgtgtttttt ttgtgatttc tcccactcgt ataccattaa
     3961 aatcactctc taaaagagca attaaaatca attgtctagt ctcatcaccc atagcagaga
     4021 tagctttgcg acattcttta aatttagacg ttatttcttg cattctttgt tgacattctt
     4081 tttccataaa atccaccctc tcttataagt atctaacagt tgctacttct ttctgtgcag
     4141 tacgtctata tttaacatct gggtatccaa ttactaatgt tgtaagaaca tgattactac
     4201 gttttagacc taaaagcttt tttaattttg gcgaattatt tgctacatct gaaaaatatc
     4261 cactaaataa aacacctaga ccataagact ctgccattaa tgccatattt gatgctgcaa
     4321 gtgaaccact aatcttatct tttgtaatta tcattattgc aataggagca tgcttaaaga
     4381 aaaagttatc gtcaatctca acttcttttg aatatttaat agctatattt gcaataggtt
     4441 ttatttttct aaaaaatttc actgcttcgt tttcataaat tgacttttta ttgtctaaaa
     4501 caatatatga tacatcttgt gaatttttag cactaggggt atacctacct gcctcaataa
     4561 tttgctttat aatttctgaa gaaacttctt tatctttaaa tttacgtata cttcttctag
     4621 atttaattgc cattagtaat tcatctgaat ctagctttgg cttatttgta agttctatag
     4681 gaggttcatc aaatcctgtc aaggtaatag cttttgtggg acatattgct gcacaatgtc
     4741 cacacattag acaatcttgt tttttaatta ctgacttttt attttctata attatattgt
     4801 ttactggaca atcattttta caaagcccac atccaatgca aagttctttg tcaacttcta
     4861 ttatatgttg gtatttcata ttcattcatc tacctttcgt ttattagttt aaactattat
     4921 aacacgtaga cattttttat attcattggt aaagaatttg attaccatta aatttttaat
     4981 ttctctatta aataaatttt tcatagaatt ttaaaatatc atagtttata cataataaaa
     5041 aagacaagct taaaacctaa gcttgccttt ttcatctttt attacaaagt aaattgcact
     5101 tacttcccat acttcttaac aattttattt tctaaaattt tatttgtgaa tcatactatt
     5161 gcatcaatac aatgtaaaat aattctatat tgattttcta tagttaaaaa agttaaaaat
     5221 tatacttatt attaattttt atactcttct tatttaatac aaagttctta tttaacatag
     5281 atttcttgtc taatatagat ttcttattta acatagattt cttgtctaat ataaatcttc
     5341 accatttgaa gcaattactt tcttatacca ttcaaaactt ttctttttca ttcttcttag
     5401 acttccatta ccactattgt ctctatctac atatataaat ccataacgct tttccatttc
     5461 acctgtacca gcacttacta aatcaatagg tgcccatgta gtataaccta ataaatcgac
     5521 cccatctata gaaactgcat catgcatagc ttttatatgt tctcttagat aatcaattct
     5581 gtaatcatct tctacataac cattttcatc agctatatct ttagcaccta atccattttc
     5641 tacaataaat agtggctttt catatctatc atatacatga tttagtgtaa ttctcaaacc
     5701 taatgggtca attggccatc cccattgact gtatgaaaga tatggatttt tagcagatgt
     5761 aaatatgttt ccttcagcca tatcatctgc attttcatcg gttctaacac aacggctatt
     5821 gtaatatgaa aatgaaataa aatctactgt atatttattc aataattcaa tatcaccagg
     5881 ttccatttct ggtgtaatac ctttttgctc catatacttt aacgcatagt taggatattt
     5941 acctttagat tgtacatcca caaagaagta attttctcta tctaactttg tagcttccca
     6001 tacatcatta ggattacaac tataaggata tacacttcca gctgcaaaca tacatccaat
     6061 taagttattt gaatcaactt catgtgctat tttagttgca attgcactag ctacaagctc
     6121 atgatgggca gcttgatatt ttatcttttc aacatcttca ccttcttcaa agcaaatacc
     6181 agcacccata aatggagcat gtaaaatcat atttatttca ttgaaagtta gccagtactt
     6241 cactaatcct ttatatcttc taaagataac attgcataat ttctcataga aacctatcat
     6301 ttttcgatta cgccatgcac catacttttt aactaaatgc attggacaat caaagtgtgt
     6361 aatagtgact aaaggctcta ttttatattt tttacactcc ttaaatatat tttcataaaa
     6421 ttgaagtccc ttttcatttg gtgtttcttc atcacctttt ggaaatattc gactccatgc
     6481 aatgctcatt ctatatactt taaatcccat ttcagcaaat aactttatat cttctttata
     6541 attatgatac atatcaatac cagttttagc tggataataa tgctcatcat caaaatcaaa
     6601 catttttagt ttccctgtaa taactgctgt tctatctttt cctgttggac atacatctac
     6661 atttgccaat cctctttcgt cttcattgta tccaccttca cattgattgg ccgcagtagc
     6721 tcctccccat aaaaaatcat tcttaaaact catagtcaaa gcctcctaaa attataacca
     6781 aagcactaga ttatgctaat acctcaatct ttactaaaat aagactgtaa ttagattgtc
     6841 ttctaattca atatttttac tttctgtttc tactacatct aaaaattgtg atgaatttgt
     6901 aataacaatt ggagttacag tactataccc caactctttt attgcataaa catcaaagtt
     6961 taatatagtt tgaccttttg taattctatc accttgtttt atacatgcct caaaacctct
     7021 tccctctaat tgaatagtat ttaatccaat atgaataagc acttcaacac ctgtatcaga
     7081 aagaatccct atagcatgta gactaggaaa taaggttgta actaccccat ctactggagc
     7141 aactactttt ccatcactag gtattattgc cactccttga cctagtacac cagatgcaaa
     7201 tgctgcatcc tctatatcac ttaattttaa tacttcacct tttataggac ttgttactat
     7261 ttctctttct aatttagtag acttgacttc ttttatttct tctttaccct tatttcttac
     7321 ttttttagac tcttctactt tctcatcttt atataaaatc atagttaata caaaagctac
     7381 gaccattgat atagctatac cagaaagagc tactattaag ttacccattc ccccatctgg
     7441 ttcaatcatt gctggaagtt caaatattcc cattcctcca gttataaatt ttctaagatt
     7501 aaagaatcca tagaaagcgc ctccaatacc actagcaata caacttatta taaatggttt
     7561 ctttaaaggc aataatattc cataaattgc tggctctgta actccaaata taccagatat
     7621 aaagtttggt attgccatct cttttagttt tttatcttta gtcttgaaaa atattgccaa
     7681 cacaactgcc gaacttgcaa atgtacaggc aaagaatggc atcataacat tatcatatcc
     7741 taaagtcata acattgttta tatatacagg aataaatccc cagtgcatac caaaaataac
     7801 aagaatttgc caagtaaatc ctactatagc acctgccaat agtggactaa aatctcttat
     7861 tgaaattaca atttgtgaaa taagtgtaga accaaatgtt gctataggac ctataactat
     7921 aagtgcaaca ggcactgtta ttaataatgt aagcattggc acaaagaaaa acttaactaa
     7981 atctggaaca cacttattaa ataatttttc acacctagaa gcaaaataca ctataaatat
     8041 aattggtacg actgttccag tataatcaat tgatacaatt ggtagtccaa agaaatcaat
     8101 atatactggt gatgcaaaca ttgttccttt aaataaagtg tacatcacat ctgctcctgc
     8161 tgatatactg ctaccttgta tagcaggata acatactgca gctcctagtg ctaatcccaa
     8221 cattggtttt aatccaaact tcttagctga agtatatcct aagaacaaag gaaggaatgt
     8281 aaataatgca tctcccgctg catttattac catataacca ccagatacat cactatataa
     8341 tcccattgct acaaataatg cattaaatcc tttcaacata ccacaagctg ccattatccc
     8401 taacactggc tgaaaaattc ctgatattat atctatacct ttatctagta tattacctga
     8461 ttttttagtt tctgaacttg tacttgaatc atctaaacca attatttcaa ctacatcttt
     8521 atagacagct tcaacatgat ttcctataac tacttgatat tgtcctccac ttttcattac
     8581 agtaacaata ccttccatgt tttttaatac attgtcattt gctatacttt catcttttaa
     8641 agtaaaacgt aatcttgtaa tacagtgtac taatccacta atattttctt ttccaccaac
     8701 attgtttact atctcttgtg ctaattgttt gtattttccc atttttctcc tccatatttc
     8761 gtttaaatta attttttgaa atttgaaggt ttggccaact caatgttacc atccaaccat
     8821 aagtataatt ttgttagtat cactcctttc aatcattctt aatatactgc tgaaaaatta
     8881 tttcacttac atatttgagt ctttaactac tttagctaaa tgtattgtta aatatataag
     8941 ctcatcatct gttaatatgt agttatattg ttttttaatg aaatttttaa ttttaactac
     9001 acattcaaac tctttattat atttagattt aataatgctt agtaattctt tgtctgtctc
     9061 accttcatgt gcgctatcta aaagcaatct ttgcgcaaaa aactttaaat gcattataaa
     9121 tctataataa aacactgatt cttcatgaaa ttctatccta aaatgatacc taactatgct
     9181 aagtacttct tgtattagct tcgtaatatc agatgccaaa gtatgacctt cacttaactg
     9241 agcattcact atatgaaagg ctataaatcc agcctcatct tctggtaatt ttatacctgt
     9301 tttgttttca ataatatcta gtgctttcat tccaatttca aactcttctt tataaaatct
     9361 tttaatttcc caaaggattg cattttttac atttattcct tctttcatcc tttgaattgc
     9421 agaatatgta tggtcactta aggatatgta aatactttca tttagcttct tgtttaactt
     9481 tatttgtgcg tattctataa tttcacttga taatttcatg tgttctatag gaatattatt
     9541 gagtaattct tgtagtttgt ttgatatttc tttatttgat attctaaata ctttatttac
     9601 tttagtttta tctattagat tgccttttga tttttgataa ccaattcctt tacccataac
     9661 gataacttct tcatcattat catctaatgt gattacaaca ttattgttta atatcttatt
     9721 aattatcatg attatcctcc ttttaagcat aaaaaaagct tatccataat aatgggcata
     9781 ctccttccta ggatactgct attattaatg aataagctta gcttgtactt aaacaattac
     9841 tacctaattc caattaatat gataaaacat cagacatatt ttgtcaactt tttatttcca
     9901 tatacttcat caatctttta tgttgctttt tgtcagttct aataattatt cttattaata
     9961 ttaacttatt tctttgcatc aatataaata caaaacaagt tatagtcaat aataataaaa
    10021 attctattaa tgtaaatagt taatattata cttcctctac tacattatct gtactttatt
    10081 taacattttt ttcaactcca aaaacatatg tcataataaa tggagcaacc aatgctataa
    10141 atataactat aagtccattt actatatttg aaatcccctt ttcccctgat aatccaagta
    10201 ctgccattat actattttgt ggaacatata aagtcacatg agtaattcct gcaaataacc
    10261 ctgcgattcc tgctcctata gatgctaaca tagcaggttt tttaagtttc aatgtaactc
    10321 cataaagagc tggttcagtt atacccatga tagctgatat ccatgcagct gatgctaact
    10381 gtttcatctt actatctttg cttcttaatg ctacagctaa tgtcgcgcca ccttgcgcta
    10441 aattagcaca aacttgagat attaatatta gcgattcttg tcctgtagtt gcaaatgctg
    10501 atatgaatat aggagtcaat gcatgatgca tccctgtcat aacgataaat ggcattgcag
    10561 ctgctaataa acaaaccatt ataaatccta accttccttg tagtaaattt attacactag
    10621 ctaatccctc tcctaagaaa tttcctattg gtccaattac tattaatgct attggcgcac
    10681 ttattaataa tactaaagtt ggatttaaaa ttgtttttaa catgctaggt gttaatttat
    10741 caatgaattt ttctatatat gacatcatcc atactgttaa aagtgcaggg ataacagatg
    10801 ctacatatat aacaccttga attggtactc ctataaatga tatagggtcc ccacttgata
    10861 cccatgcaga gaaatttgga tgtaaaaaca cacctactac tataactgct attgatgtat
    10921 taacattaaa ttttttagct gcatttattg caagtattat aggcataaag taaaatgcta
    10981 catctcctat tatatctaat actctatatg tacttgaatt tgatgatagc caattaaaag
    11041 tggtgcaaag agataatata acttttatca tcccagatgc tgtaagggct ggtatcatag
    11101 gtgtcataca accagttatt gtatctatta tattatttaa aatactattt tttttatttt
    11161 tattttttat atcgctttta atatctcctg tggtatttat ccccttattt attattgcat
    11221 taaatacaac acctacctca ttacctatta taacctgata ttgagttgaa gttgagttta
    11281 ctccaactac cttatctata gattttaatt tatctgcatt gactttcttt tcatctttta
    11341 agatgaacct taatcgtgtc atacaatgag ttaagtcaat tatattatcc tttcctccaa
    11401 ggccatcaat tatcaattga gctacttctt catatttatt cttcatacct tatcctctct
    11461 tttaaaataa tttttaatat aattttaatc caaattaatc tttttactcc aagcttgtaa
    11521 tagtgtattg caatttaata agctagtatc ttctacaata tggtcacatt ttcctagtac
    11581 ttcttttttc cccacaccaa ttgatgtcat attagcagca tttatagctt taatacctga
    11641 ataagaatct tctattccta cacaatcata ttgttttaaa tttagaatct tgctcccttc
    11701 aataaaaata tcaggatatg gttttcccct ttttaataaa gatggattta ctatacaatc
    11761 aaattcatct tttattccca aagattctaa tatcctaggt gcattcttac tagcagatgc
    11821 tattcccaat ttcacattat tttttttaag ttcttttata agctcattta tccctggtaa
    11881 tatatcttta tatgttaatg agtttattaa ctttatataa atgttatttt tttcttcaca
    11941 cacctttaac ttttcctctt tagtataact atctacttta ttagcagata acaatatttt
    12001 atctaatgat tcttccctgc ttatgccttt taatttttca ttaaaagttt catctatttc
    12061 tatatctagc gattttgcta tctcatgcca agcttcaaaa tgatacttag cagtatctgt
    12121 tataactcca tcaagatcaa ataagactgc tttcatatta attactccct ttaaaacaat
    12181 tattaacttc tattatgttc tttgataatt ttatttcttt attatcatgt aatatggtta
    12241 tatttctacc tttgattaac ttataataag atttatattc ttctatattt acagaaacta
    12301 aattatctct aaataatata ttaaatttaa tatttttcca gtgtttaggt atccttggtt
    12361 caaaacttaa tttatcattt tttattttca ttcctgcaaa tccatatact aaactcatcc
    12421 atgttccacc catattagca gcatgtattc catcacttgt atttttttgt aggttattaa
    12481 tatccattaa tgctgtgtcc ataaaatagt tataagcttt ttcatgattt ccaatttcac
    12541 ttgccatcat tccaaatatt gaccttgaca aagatgaatc atgagtagtt attttttcat
    12601 agtattcaaa atctctcttc ttttgttcta agctaaactc atcagggaaa agcaacgctg
    12661 aaagtacagt atctgcttgt ttatttactt gatatctata tattgttaat ggatgataat
    12721 ggagaagtaa tggatatttt tcttttggtg tatttttaaa atcccatact gatttttcta
    12781 aaaatgaatc gtcttgtttg cttattttct tctcttcatc atatggtaaa tacatatttt
    12841 gagcggcatt tatccagttt ttcacttcat attcttgtaa tttaactttt ctaaatactt
    12901 catttgaaaa taaattatgc ttaaatttat ctaccatctg tactgcatat attaaattat
    12961 acttagccat taaattagtg tagtaattat tgtttactat tgctgtatat tcatctggtc
    13021 ctgttactcc atttatacag aatttattat tttttgattc tatataatct ccaaattcaa
    13081 cccaaaatct tgctgtttct ataagaattt ctaagccatt ttgcatcata aattcttcat
    13141 cattagttgc ttcaaaatac gttctaatac cataagctat atctgcattt atatgaaact
    13201 gtgctgttcc tgttggataa tatgcactgc attcattacc atttatagtt ctccatgaat
    13261 ataagcaacc tttatttatt ccaagttctc tagctctttc tcttgatgca tctaagattg
    13321 agtatctata atctaataaa gctctagcaa tggatggttg agtatatata aaaaatggta
    13381 atatatacat ttctgtatcc cagaaataat gcccctcata gccatcacct gtaagacctt
    13441 ttgctgatat attagtcttt ccatctcttc ctgctgattg ataaatatga aataaattgg
    13501 tttttatccc cagttgaaga gttttatcgc cttcaatctc tacatcagag gttgtccaaa
    13561 actcattcat tttctttctc tgaatatttt tgactttatc aaatccaata ttacatgctt
    13621 ctcttaaaac caattctaat gattttaaat gtgcttctga ttctaaacat tttaacgact
    13681 ccagacattc taatgatttt aaacgttctt catttagatt taaatcagaa tatactctac
    13741 tatagcctac aacaatttct aaatttaacc tttcatcttt tttggcatag acttctattt
    13801 ctcgctcaat acattcatct gaaacattat aggtctcatt tgtaatattt ccacaagtaa
    13861 tatatgaatc aaacccacac cataacccta atctacttct ttctgtaact aaattcataa
    13921 aatacttatt gttatatttt tttacattaa ttttaaattg cttcttattt atagatgcca
    13981 ctcttgggtc atctactttt tcacaattaa acttctccat actattttcc attttatttt
    14041 taaattttat ttttccatta aaattcaatg gtgttattgt atatgaaatc atcattaatt
    14101 cttctatatc ttgtgatact aatctttcta tagatacttt aacttttcta ccacaagagt
    14161 tttcccatat aaatgaacgt ttaagaatcc cttcatttaa atctagtatc ctagaatgtt
    14221 cacttgtaat accttttgat aaatcaaaat aatctccttc aatagagaaa tttactatat
    14281 gagcattagg taacttacag atagtctgat tttgttttgc atagccataa gcgctttctc
    14341 catatgtaat tggagattct tcataaaatc catttacata tgtacccata ttatctacat
    14401 actcattatt aaaatcagac tcttcaatat tccctctaac tcctaaatgt ccattagcta
    14461 gtgtaaacag cgtttcattg gattttattg tatccttact aaacccttgc tctataagtt
    14521 ggtccttagt agtaaatatt aaactcataa taacactcct ttcttaaaat gaattatgca
    14581 tgagtttcca tgtcattaaa taaaatttct ccatctgttt ctattacttt tttataccaa
    14641 aaagcacttt gttttttagt tcttttaaat gagcctcttc catagtcatc agaatcaaca
    14701 tgaattatgc catatcgttt tgtcatcttt ccttcactta cactggttac atctatacat
    14761 ccccacataa gatatcctat aagctctatt ccatcttcat ttactccaag aatcatattt
    14821 ttaatatgtt ctttcatgta atctatacga taatcatcaa ttatttttcc atcttcattc
    14881 acaatatctt gagtacccag tccattttct actataaata aaggtaactg atacctttca
    14941 tataactgat tcatagttat tcttaaccct acagggtcgt tttgccatac actatttgat
    15001 tttggaagat atggattttt tatggtttct ggtccgtttg cctttgattt ttctaaacct
    15061 tcagctctag ctgaactaca agcactagaa taatagctaa aagatacaaa atctacagta
    15121 ttatccttaa gtgttgataa atcttcctct tttattatta attttatttg atttgatttt
    15181 aaataataat tcataaagct tggatacaca cccctaactt gaacatcaga aaaaaacaaa
    15241 ttataccttt catgctctaa agttgcaaat acatcttctg gtttacatgt gtatggatat
    15301 gtttttccag cagctaacat acacccaaac ttaaattctt tatttatata ccttcctatt
    15361 tctatagttt ttgcattagc taataattga tggtgtgctg cttgatattt tttctgaagt
    15421 tgattttcat cagctataaa agttaaccca gcacctatat atggaatatg cattatcata
    15481 ttcatttcgt taaaaggaat ccagtatttg acatcatctt tatatctttt catcaaaatt
    15541 tcagcatatt ttacatataa attaaccact cttctatcag cccacccaga atatttttca
    15601 actagagaat aaggtatatc aaagtggctt atcgttatta atggctctat attatatttt
    15661 tttaattctt ttattatatt atcataaagt tgtaatccct tttcatttgg ttcactttct
    15721 tctcctgttg ggaatattct tgaccaagat atagaaaatc taaaacattt aaaacctatt
    15781 tctgctaaca ttgctatatc ttctttgtaa ttttcacaaa atttaatccc tatatgactt
    15841 ggatagtatt gattattttc atttaaaata ttatcctcat ctaaacatac atcttttaat
    15901 ctcttatcat ttaatgggag tttatcaaac tgagataaac cttttcctcc atctaaataa
    15961 aatccttcac tttgattggc tgaaattgcc cctccccata aaaaatcttt ccctaatttc
    16021 atgcatctac ctctttcaca atataaagtt ttataatttc tatctcatat ttagttataa
    16081 gatttttttc atactatacc ttttaaataa ttcaatttaa aaatccaatg atatttttta
    16141 ctcactataa ttaatattgt ctattttcaa tactttcata ttaaatatca atattagata
    16201 tctatgtata taattatata tatagcaaat acatttttat atcctcatta ttgttatctt
    16261 attctcatat attgctgtat atttatatat ataaaaggag ttatttcgaa atagaggttg
    16321 tattgagaac taaaatttag actttataaa tgaatggaat tttcattgtt gaaatactga
    16381 aaatatattt gatttcatat aaaagaaagt gcctcatgaa ctaagttcat tttgagacac
    16441 tccctttttt tccaagctat tatatctttt tttaaattct aatggagaga ctccaatttt
    16501 ttctttaaat actctgtaaa aagtttttgt acttccaaaa ccaacttctt caaccaaatc
    16561 tacaatggat atattgttat taagtaatat ccactttgct ttttctaatc tatattcatt
    16621 taaaaaagtt ataaatgttt ttcctgtatt ttttttgaaa aatttagtaa aataatatac
    16681 actaaatcct acttcataag acacatcttc taattttata ggttgtttat aatttttttc
    16741 tacatatttg aatatattgt tcaatctctc taatatctct ttagagttta tttcatattc
    16801 tactgtattt tcttcaattt ctctaggaat ctgtctatat aatataggaa ttaaattata
    16861 cattttacct tttattgcat aactatatcc ttctattttg tataggtctt cattgtagat
    16921 atctatcaat atatcgaaca ctgactttct tatttttgct gaccaatctc tactacattt
    16981 ttttatacta ctgaataaat taattaagct ttctttttcc tcatttaata aaattaaatc
    17041 attaaaaaaa gatatatcaa attgaaatac taatctttca cttcccggtg atggcagtat
    17101 ataatgaata tctcctcctt ttattatcac tatctcgcct ttttttaatt gcataggctt
    17161 gtcatttata aatagattta ctacaccttc tgttataagt aatatttcta tttccttatg
    17221 ccagtgtggt gttgttaata cttctccttc atttgataga ctacgaaaag gaaattcatg
    17281 tattaattta ggcatttcta aatatattgc catatatatc ctctcctctc tagtgtctaa
    17341 aaattaattt atactattta aaagaataca cattttattt taaaaacctc aaatttataa
    17401 tttatacaat acctacactt cataaaatat atctaatatt tctttttttg tatgtgcatt
    17461 taaaagtctt tcacctatat ttttaccacc taaaatgtaa gctattttag atattaatat
    17521 catatcttca ttgcctccag attgtggcat agcaaacata attattacct ttacaggtaa
    17581 gccatctata cttggccaat ctacaccttt tttagattta cctattacta cagaggcctt
    17641 ctttacatat tttgtttttc catgtggcat ggccatttga taacctatac tagtagagcc
    17701 tattttttct ctatgtttta atgcctttat aaacttactt tttaaagtta tacttcctgt
    17761 atcgtataat ttatctacta attcctgtat tatgccttct tttgtggttg atttcaaatc
    17821 taaaataatg ctttcttctg ttaatatttc tctaatttcc atttgttttc tccaatagat
    17881 tattcttaaa taatatttta atatcctctt tgctcttgca atctattata tagtttatat
    17941 agttcttttg cctatataaa tttgatattt ccattaaaat attctttaaa aaactttgat
    18001 tactaatttc taaataaata tcaatcgttc tagtaacatt attgacattc attatccctt
    18061 tatttaattt actttgctta tgtatatata tatttaaatc ttttcctaat gaaatagatt
    18121 catatttact ccctaaattc acacctatta aactttccat ctgagctaca tcaaaattaa
    18181 aatatatatt atcttctaaa tatattccta ataagtttgt atctaagttc atactttttt
    18241 taggtttaga aagtaaagca ttttttatat tattaatatc attttccatt aatagtactg
    18301 atacaactat atgtaattta tctttcaaat ctaagtttac agtagatatt acaaagtcta
    18361 catcatctaa atttcgctta ctcaactgat gcataggaac tatatcaact atagtccatt
    18421 caggaaattc tctttttaat ctggctgcaa ggagctgaga tgttccatat cctgtatgac
    18481 aaactactat tactctttta ctactcatat ttctttctat tgccgcttga aaatatgtgg
    18541 caagatacga gacttcatct atactaatat tcttcagatt atcatactct gtcataatat
    18601 ttatagtcat catacataat cccagcacat ctgaaaatcg ctcttgtatc tctcctaaca
    18661 acgggttttt tatttggata tcatatctta atctgtttaa cataggcctt acatgagatg
    18721 ctagactttt ctgtagtaag tcatcatttt tgagatttat atttaaaaat cgtgacatat
    18781 tctctatcat tatagatgaa actttttcac tttcacttaa tctatctgat tcatcattgt
    18841 aactactatt attttcgcta ctaaatccag atgatactaa aaaaatatat atgtacataa
    18901 tttcatcttt cgttattttt actctgtatc tattttctat tttatctata agtgtagtga
    18961 catttttata tactaactcg tccaaattat ctacagaaat ttctctttct tcctgagatt
    19021 ctatttgatt accttcttcg attctcttta aacatataag tatatgggta attaaattta
    19081 tatagtaggg ctgatttata gtatatccta aattgtattc taattctgta attatagttt
    19141 ctacaaatat aatagaatca atatcaaata aatttatcaa tgcactaaat gtagcagaat
    19201 ctaatcttgt taactcagat atatcatgtt gttcataatt ttcatctaat aaatcatcca
    19261 tcattttggc aatcgatttc cttatatcca cttctttacc tataatctta gttccttcta
    19321 aagttttatt aagttttaaa ttgtattctt ttatccatgc ctctatatat ttaaaatcat
    19381 ttactataga agttttactt acataatatt tatctgctaa ctgatttatt gaagttatat
    19441 tatttgaatt tagtaataaa tactttaaaa tctccattct tctctgctct actgataaag
    19501 atttattttc cttcgattgt atatttaaac tattaattaa gtctatgttc ttctttgcta
    19561 aatcttctat taatattcca tagcctcttt ttatatcaat ttttatatta aaagtttcta
    19621 aatatttctc aatcatcttc aaatcttttt gtaaagtttt atcagataca tttaatttat
    19681 ctttaaagta ttttataggt ctatatttat tttcgtttag tatcaattta agaaattcaa
    19741 tttgcctcga cacaagcata cttagccctc cctacctatg tttatatatt tctatgttta
    19801 tattaagtac tattttaaca tatttactaa ctatgtaaaa ttactaagat acttctgtat
    19861 cataaaagaa tttatgatac accttactaa attgatataa tagataatat aatttcaaaa
    19921 taaaaattaa ggatatttag aagtagttaa ctgattctaa atatccttat tattattcta
    19981 tatacttgtt gttattccat taattatttt tactattatt tataatttaa gcaccaagta
    20041 attcaacttc actattttca ctccttatag taggctttgt tacccctata atcaatgctg
    20101 ttactactgt accaatcaat atacaagcta tatatgcaac tggtgcacta catgcaaatg
    20161 gtattacaaa tattccccca tgtggtgcca ttaaagttat atctaaactc atacatattg
    20221 ccccacctat acaagaacca attatatttg ctggaatcat tcttaatggg tctgcagctg
    20281 caaacggtat tgcgccttct gttatgaaag atgcccccat tatagcagtt ggtagagatg
    20341 actttctttc ttctttagta aacttatttt tgaatattaa catagccaat gatatcgcta
    20401 atggaggtac cattcctcct accattaatg ctgctgatgg ttcaaatata ttacttgaaa
    20461 acatagccaa tccaaaagct gaagctgttt tattaatagg tcctcccata tctgatgcca
    20521 tcatccctgc taatattgca cctaataata ctttattagt tccagacata ctttgtaacc
    20581 aagattgtaa agcttcattt aaccatgatg ctggcgtatt aactacaaag aacattatag
    20641 ctccactcgt aaatgcaatc aaaagtggac atatcaatac agcatttact ccttttaata
    20701 catctggtaa attttctgtt atcttcatta ctcctaaagc tatatatcct gttgcaaaac
    20761 cagctaccat accacctata aaacctgaac ctccaataac tgccataaaa ccagctatca
    20821 tagcaggagc aaatccttgt cttcctgcta ttgatttagc tataaaacca gcaagtatcg
    20881 gtataaataa cttaaatgct gaatcgcctc caagttgtcc aaagaatcca gctatagggt
    20941 tgtatgtttc atgagttggg tctgatgcaa atataccaaa cataaaagct atggctatac
    21001 caattccacc tatcactaca aatggaatca tttcagatac accactcatt aagtgcttat
    21061 aaacaccctt tttctctgac ccttgaagca tttcttttga atcttctaaa gtctttccac
    21121 ctggtttaat ttctttagcc attccatttt cagcgtttat aattaaattt ttagctaatg
    21181 aaacattctt agcatctact actttctttt gtagcacttt ctttcctata aatctactca
    21241 gttgaacttc tttatcacaa gctattatta cgtattcagc tctttttata tcttctttag
    21301 tcaacttatt ttctacacct atagctccat gagtttctat tttaacttca tatccaagtt
    21361 cttgacctgc ttcctctaat gctttttttg ccataaaagt atgagctata cctgttggac
    21421 atcctgttat cccaactata agacctttat tttgattatt actaaaatct cctgattctg
    21481 cagctttatt attaaatata cttaatattt cgtatggagt ttctgcactt agtagatgct
    21541 taagaaaatt ttcttccatt agatatgtag ctagtttaga tataatctta agatgttcat
    21601 ctgaacctga ttctggaact gctatcataa aaaatgacct aagtttttga ccatcattat
    21661 ctgtaatctc tctatctgtt cttaaataca tcattacagg ttgatttact acatttgact
    21721 tagcatgagg tatagctatt aaattaccca tattagttga tgattctttt tcgcgtttat
    21781 taatatcagc tataaacttt tctttattat ttatataatt tccatggtac aaatgatttg
    21841 ccatataatt aattacatct ttttttgttt gtaattgttt atctagtaca atacaatcgc
    21901 ttcgtagtat tttacctatc ataaattctc ccctcctttt aatttgttac ctcataatta
    21961 atttttattt ttataaaagc actttaactt atctatagca ttgaatagat tcattttaaa
    22021 ctctataact tctcttgcag attttataca tggtggatat atagtatctg gctcatataa
    22081 gcttgggttt tgttctaata gttctctgca cttcttataa tatgccgact taacatcact
    22141 cgaaatattt attttacaaa ctcctagttt aactgcttgt gctatttctt catctggatt
    22201 tgatgaacca ccatgaagaa ctaaaggtat atctactact tctcttattt cttttaataa
    22261 atctagttta agctctggtt taaaaccttt tggatatata ccatgtgctg taccaattgc
    22321 aatagctagt gtgtctactc ctgttttttc aacaaaatcc ttagctaatt ttgaatctgt
    22381 atatattatt tcatcagtac caccttcact tgatgttcct gttgttccta ttgttccaag
    22441 ttctccttct acggacacat ttaatccttt tgctatttct actatttccc tagatatagc
    22501 tacattctct tcatatggta aatgtgagcc atcaatcatt actgatgtaa atccacatct
    22561 tattgccctt aatatttgtt ctttattttc cccatgatct aagtgtatta ccataggtac
    22621 tttactctta tttgcttctt ctatgcaact agctacaaag ctatctccta gaaaacttag
    22681 ctcattgggg tgtattgcaa gtattactgg tgcatttttt tcgttagcac tctgtactac
    22741 tgctttaagt atttgcccac ttcctatatt aaatgctggt acagcaaatt gattttcttg
    22801 tgccactttt agcatttcct tcatatttat taacatattg tacctcccga tattttaaat
    22861 tttaggttga atttgcttct tgttaatttt gttgttgttt atatttaaat aatatcagtg
    22921 taatgaagat cagaaaataa caatcgtttt ccttagtgaa aaggaacttt tattatacac
    22981 tctaagttcc ttttcactaa ataattttta gaagtctgca tcatagttaa ttatatttct
    23041 catatacatc ttctcttttt aagtgtttta tgctttagcc ttcctagatt ttataataaa
    23101 caattaagat acattaacta taaatttaaa gatactcatg caatagttaa tgctatatta
    23161 gagtcaaaaa aattaaaaag atattagcta tttggccaat accttttctt ggattccaat
    23221 agtatatatg atttatagaa atcatactca cgattatcta atgttttact tccataaact
    23281 ttacataaaa caccaaagtg acaccctcca aattcatctc tagctaataa agtgatttgg
    23341 ttttctaagc agcaatttat aaattagcct ttgttatctt atgtaaatct ttttctatct
    23401 aatttaaaaa ttattcctaa tgctatatag catataccaa ttactaatac accataattc
    23461 atagatactc ctatcttaaa ttcttgcata ttagttacaa tagaaattaa aataggttta
    23521 ttacaaacac cataaagcaa ggctgacatt gtatattatc caattgtatg aatgaatact
    23581 aatatagctc cttttaatta aatgatgcta tataaatcat atttatccca atttttaatc
    23641 taacctattt atatgtatat tcctttttaa taaaaaaaga tattgactaa atagtcaata
    23701 tcttttagtt gatttaaata cccacaattt taatctaatt tttaagtgtt tccttaacat
    23761 aatcttataa atattaaaat ttatctacct ataaaatttc tccattaaat tttattacat
    23821 tttatcttaa aacaattata atctgacctt aatcacatgt tatattatat aaatattttt
    23881 aacaaactta atgattaaat aactatattt tattatccat cttataaatg tttataaatt
    23941 ttccactatt cttcttcaat aaattcaaac aaattttcta ctgtagtatc gaatacttta
    24001 gcgatatcca cagctaactt caaagaagga ttatatttcc cattttctaa gtgtacaata
    24061 gtctcacgtc ttaccccaac caatttagca agttcatttt gcgtcataag gagtttttct
    24121 ctgtattctt taatttttgt tttcatcaat attgccactt agttacatat ccccctttta
    24181 tcaaagtata tatacaacac taatttagat aaagactgta taaataaaac tgcaatgagg
    24241 attatacctg tatctaggtt tgatatattt atattacttg tataaggtgt tgcaaagaaa
    24301 atagatatta ttactataga atatatcatt atttttattg caatcttatt aacctttgat
    24361 agtataaatt cagatgattc atcaactaaa tcattatatt ttttattata aattgaataa
    24421 catccaaaaa ctattaacca actcaaccct ggaagagaag cagtgcttgg acctttaaaa
    24481 atatacttag tggataatac agctataaaa aaataagtta ttacaagcaa ctccaggata
    24541 agctttgatc ttacaccagt ttctgattta gacatataaa atcactcctt aaaaattata
    24601 ttctctatac tctttaattt tcgtttttat caatattatc acctagttgc atattccctt
    24661 tctatcaaaa tgtatataca aaattaattt agataaagat tgtataaata aaatagctaa
    24721 gagaattaca cctatatcca aatttgatat atccaaacct cttgtataat ttgctgaaaa
    24781 gaaaacagct attagcaaaa tagaatataa cattattttt gatgcaatat gatcaacctt
    24841 taataacata agttttgacg cctcgtcaac taaatcatta tattttttat tatacatgaa
    24901 gtcacatgcc caaaaagcga ataaaattat aaaagtaata caaagatttc catatttaaa
    24961 aataaacttt tttaataatg agtctataaa aaaataggat atcataagta actctgaaac
    25021 aagatttgtt ttaacaccaa gctctgattt agacatataa aatcacccct taaaagttat
    25081 atatttataa caccttatgt tataaatata taacttttcc aaataaattg caatagaata
    25141 ttgaaaatat tcaataatat cttcataaat atattttata aaaggtttta taataaacat
    25201 tacaatacag tactaaatta gtttatttca tctatcatct caatcatatc atttactaac
    25261 tattattcta atgagcatat aacattgaaa tttataatta tacaacctaa atgcctccca
    25321 atgtaccctc aaaaacatca tttcctgtaa ctgaagtata attggtatat tttatcactg
    25381 aaataaaaaa acactagtca ataaagacta gtattttcaa gtattttatc attctttttt
    25441 taattattgg agacgaatca ttagaataat gcccataatt tatctatatg caaattctaa
    25501 atttaaaata aagtttcaga taaatttact attctatgct atgatacaac agaaaaaact
    25561 gaaatctatg agtggtagct tcatataatc ctagttccta cagtaatcaa aactgaggtt
    25621 tattctatat gtaactaatg ataaatttta ttataggagt tattagctct atttgtgtta
    25681 ctataagtag taattatata tatgataatt ttttaacact tttctgttgg ctatatagaa
    25741 agtggtttag aatttaaatt taaataaaat ttaaattcac caaaaagaaa tctatattag
    25801 aaaccactac tctattccac cagattgtaa ttttttgttc tttatatcac aatgctatac
    25861 catattaaat tgaaaaataa attttaaatt tatttgttac aattcattaa ttcaaaaaaa
    25921 tattttgagt catgagtttt gtaaagattt agccatgaat ttaatgcttc tgattcaaaa
    25981 acatctaaaa gtttcaatac ttgaaacgta aattccaacg gagcaattcc tgaagccgta
    26041 actaaatttt catcactaac tacagattcc gttttataat atttttctcc agagtaattt
    26101 ggtattacca ttttaagaaa ctctaagtca ttacttgtat gatttctaaa atctaatagc
    26161 ccttttttag ctaggcctaa tgtagctcca catatggctg caactataga atcttgtatt
    26221 aaagcttctt taactttttc taatattatc tcatgattca tggataacca agtatttccc
    26281 cctggcaaaa ttaataaatc cttactttcc atattaaact catcaactgt aatttcaggt
    26341 aaaactttta acccacccat tgttataata ggatttttat caattcctac agtaattact
    26401 tttagtggtt ttaatccttt tttaaaatat cttcctgtat ttaattcagc agttaaatat
    26461 gccacttccc aatctgacat agtatcaaat acatacatat atacttttct atttttcatc
    26521 ttttttactc cttatgtaat taatttatat atctaattat aaaataactt aactgacata
    26581 ttcagtcagt taagctatta aatttgataa taatcaatta attctagtaa atcttcaatt
    26641 attttcttcc taaggcttag tggttcaatt acttgtattg tctttctata aggtaaaagt
    26701 atatttggta tgtacttgca tattacttcc tcttcaagca taaatattat tttattaggt
    26761 gttctttctt tcaagtagtg ccctaaaaac caatgttgac ttaaactatc taaagaatct
    26821 atactccctt ctacaactaa ttgaattata ttttgttcat cttttatttc aggtataatt
    26881 ccttttataa aaaattcact tgctgaaaat tctgtcggtc tgttaaatgt atttgatgtt
    26941 tctatgattt cactaatcct atccactctg aaactacgta cctcatttct catattacaa
    27001 aatgcaacta cgtaccaatt attattccag tgaacaattc catatggatt tataattcta
    27061 tattttgatt ttgctttacg acctgcatgg tagttgattt ctacagatag ctcctttaat
    27121 atactattct ccaatttttt aagtactgat tctatagaca ctttcccaat tggttttatt
    27181 acttcaaggg ctcttaagtg gtttgttaaa atatcttctt gtttttgatt tgaatacatt
    27241 tttaacttta atatcgattt atctaatgct tcgtctaaga agtatccttc ttttttagca
    27301 aatagagctg catgaagtag agatttttgc tcttctatat caaaaaaaag aggtgcttta
    27361 gtaaaattat ttaaaaggct atacccacca ttatgacctg tatctgaaat tataggtact
    27421 ccactcgcag aaagtacatc aatatatcgg tacactgttc ttatatttat ttctaatttt
    27481 tcagctatct gttttgctgt aatttttttg tcagagttta atatccacag tatagacatc
    27541 atattgtcaa ttttagccat gtagtttcac ctctttctat ttgttatata aagttattat
    27601 ataacttctg atcgattttt tacaaaaaaa cattagtaaa ctgctaataa tttatactaa
    27661 gatttatttc aaatatttat agagagtctt tttctatagt taagttatcc attaaattcc
    27721 atagtagtgt atctacttca attgatatat tttcaactac acttctcgtt atatatcaat
    27781 tttctttttt aaagatttta caactgatat ttagttcaag atttatatat attctttttc
    27841 aaaaaccttt cagtctcaaa ttaaaacttt tttgttttaa tttcttcaag atatagaaaa
    27901 agtcttatcc taatttattt aagctaaaat tcttatattt taaatttttc tttaaaacta
    27961 aaatatttat tatcatcttc agcaacaata taaatctact aattaaatac ctaatattta
    28021 ttcatatttt tctaaacata attactaaaa ttgaattaat gatatcaatt ccattaatct
    28081 cttttaataa aaaattctct tttctatatg aaaattattt caaaacttta aagttaaata
    28141 caaaaatgac tataaatagg tttttattta cacaaatcta tctatagtca ctatagttta
    28201 tccaataaaa taataaaata aatatgtaca caataaatgt tatttacgtc ttaagtattt
    28261 atttgttaga tttttaatta aaaaaaacaa gctaatgaac attaatgcta aatctagcat
    28321 tatattgctt tgatctcctg tttgtacatt ttgacctaca ttactatcta aactttcatc
    28381 tgtatctata tttatatctg gttttccatt cccatctgta tctatattta tatccggctt
    28441 tccatctcca tctatatcta tatttacatc cggctttcca tctccatcta tatctatatt
    28501 tacatctggt tttccatctc catctgtatc tatatttata tctggttttc catctccatc
    28561 tgtgtctata tttatattcg gttttccatc cccatctgta tctatatcta tatctatatc
    28621 tggtttgcta tttcctccat tatctgggtc tggtttacta tttccaccgt tatctggatc
    28681 cggtttgtta tttcctccat tatctggatc tggtttacca ttgccaccgt tatctggatc
    28741 tggtttgcta tttcctccat tacctgaatc cggtttgcta tttcctccat tacctgaatc
    28801 tggtttgcta tttcctccat tacctgaatc tggtttgcta tttcctccat tatctggatc
    28861 cggcttgcta tttcctccat tatctggatc cggcttgcta tttcctccat tatctggatc
    28921 tggcttattt agatttggat tacctgtatc ataacctcct gagccagtat ctacattttt
    28981 atcaggcttc caataatcat ctactccatc attatctgta tctattgctg gacgattata
    29041 atctgtatca gggtttccat ctccattggt atctatattt ttatcaggtt tccaaatacc
    29101 atctccattt ccaccttctg tactaggctt ccattcacct gtattatcag tatctatgtt
    29161 aatatctggc ttccaatcac cactcgtatc tatattgata tctggccttc catcaccatc
    29221 agtgtctata tttatatccg gtattccatc cccatctaca tctacatttg tcacatctaa
    29281 ctttaacttc ttttcatcct cactaccttc aatgtaattt atatcatctc caatatattt
    29341 tacagtaata gtttgttcag tagtaaaaat atgatgattg ctatctaaag gtctccattc
    29401 aatagatgca gtactataat tatgactctc actaccctta ttatgagttt ttaattctac
    29461 tggatcttta tattcctttc cattaatata gaattgtacg taacctcttg gagaggcaca
    29521 atctggtcct tctttcttat ctggtgaaat agtaacattt aatgtaaacg tatctgttgg
    29581 tttaaaaaca tcagttttag ctttagactc ttctacaact aatgaagttt ctgtatcagc
    29641 aggaataatt tctgccttat aatatgctct atgcccccaa taagcttcat taaaaggata
    29701 tacatttgaa aactgtgttg atgtaatgct taattgatat tttccagcat caacttgctt
    29761 tgtaaggtca tcacttccta aatttgtatc tggttccatt gtttcctcat ttaaacgttg
    29821 agaactaata gtcataaatt ttttatctgt gagtttttca cctttaggag taattattgg
    29881 aataccccca tcttttaata tccaatctaa aaatgatttt tctacatctt cttcaaatgg
    29941 taatccatca tatcttttaa taatcaaata tggtggagta tcatcaatag taaattcttc
    30001 atattgcttt aaaaattgag aacctgaacc tatatcttta acataaaaat catctggttt
    30061 tatatttcct ccagtaattt tatctataac aactaaatta acagatactt cagatccctt
    30121 aaattgttca gaaaaccata agtaaagaac cccttgatca tctgtataac taggtgctcc
    30181 ataaggataa atttttccat caattagcat tttaaaatca tcaactaatg tagtactaac
    30241 tttatcttgt cctaaatact ttaaagatat tttattcata aaaacttttg ttttcttttc
    30301 taaatcaccg tatgcaactg ctccacctaa acttttgaat gttgttgctt ttaatgaacc
    30361 acctgttact ataacatctc ccgttgtagc acttaggtca aaaatccaat ctcccactcc
    30421 tgtcatataa ggtaaaatcg ttcctccagt tacaagtata cgatatcctc tatttgttcc
    30481 tggattaaca catccatccc caaatgcact accatgtgca cctccatatg aataggaaag
    30541 tccaccatta attgtaatat tcccactata accagaacct gtgctaggat ctactactga
    30601 gggacttaat gcattctttg ttgttgtata gtatcctcca cctattccag ctccatggta
    30661 tgcaccttta gcagttatag taccaccatt gattgtgata tctccaccac taccattacc
    30721 gcctccacct attccagctc catatcctgt attacgactc gattcttgac ctatagcagt
    30781 tatagcacca ccattaataa taatatttcc tccactttca gtatttccac cgccaatacc
    30841 tgcagaataa taatttccaa caacttttaa acttcctcta ttattactat ctagtagtgt
    30901 aaggcgatct ccttttttta acttgtctcc attttctaga gttacatctc taggaatttt
    30961 tccaccctca ggaactataa actcgccttc aatatctcta tttacaacag aatcatcaat
    31021 aattagagta gtaccttttc ctgctctcat acctggataa tatacatcac ctgactctag
    31081 cttgttttca ctaccatctt gtaatataac atgtgcatat gcaccaccat ctttatctgg
    31141 tgttaaagta aatgggctat tagatgcagt tttaatattt actccatcaa atattaattc
    31201 agcttttaca tctttaggta taacaatcct atgtgttgtt ggagtatttg gattattatt
    31261 ttgaattgtc atttgttttc cactaagaat agttaaaacg ccacttgcaa atttaaaatc
    31321 gacatttatt tctccaccac taattttaaa gtctcctaca gatgtaggat cttctgcagt
    31381 ggcttcttcc acaactaatg cattcatatc tccttctgca tttcctgcat tagaatcttc
    31441 ttctgcattt cctgcattag catctccttc tgcatttcct gcattagcat cttcttctgc
    31501 atttcctgca ttagcatctc ctcctgcatt tcctgcatta gcatctcctt ctggatttcc
    31561 tgcatttcct gcattagcat cccctcctgc atttcctgca ttagcatccc ctcctgcatt
    31621 tcctgcatta gcatcccctt ctgcatttcc tgcattagca tcccctcctg catttcctgc
    31681 attagtatct ccttctgcat ttcctgcatt agtactttct tctatagtat ctgcgaaagt
    31741 atttgacgca ttaaatgatg ctactgatcc aagtcccatt gagatactta aaatcattga
    31801 tagtgctttc tttttacatt tttgttgcat aaattccccc tccccttaac aatttttaat
    31861 atacactgta tacatcctta tatacactct aataattctt aatatacact gtatacatcc
    31921 ttatatacac tctaataatt tttaatatat acttaaaact ta
//
LOCUS       DAEPXW010000041        31928 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.042, whole genome shotgun sequence.
ACCESSION   DAEPXW010000041 DAEPXW010000000
VERSION     DAEPXW010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31928
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.042"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            111..809
                     /locus_tag="KRM55_001895"
     CDS             111..809
                     /locus_tag="KRM55_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594141.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIEE
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            987..1877
                     /locus_tag="KRM55_001896"
     CDS             987..1877
                     /locus_tag="KRM55_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594142.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(2270..3226)
                     /locus_tag="KRM55_001897"
     CDS             complement(2270..3226)
                     /locus_tag="KRM55_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1594143.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            3929..4924
                     /locus_tag="KRM55_001898"
     CDS             3929..4924
                     /locus_tag="KRM55_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1594144.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAILSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            4902..5765
                     /locus_tag="KRM55_001899"
     CDS             4902..5765
                     /locus_tag="KRM55_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH1594145.1"
                     /translation="MSIMSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFKMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            5793..6557
                     /locus_tag="KRM55_001900"
     CDS             5793..6557
                     /locus_tag="KRM55_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH1594146.1"
                     /translation="MLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLMFNSIYSHVDS
                     IGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYITKPLDPLFRLT
                     FENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLLFYDVCIILRT
                     VSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMSTIPTQILAGT
                     ITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            6842..8221
                     /locus_tag="KRM55_001901"
     CDS             6842..8221
                     /locus_tag="KRM55_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1594147.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIF
                     KYKNRYKYM"
     gene            8669..9382
                     /locus_tag="KRM55_001902"
     CDS             8669..9382
                     /locus_tag="KRM55_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594148.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDINEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(9654..11192)
                     /locus_tag="KRM55_001903"
     CDS             complement(9654..11192)
                     /locus_tag="KRM55_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1594149.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIANNFYSIDNEINKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            12074..12529
                     /locus_tag="KRM55_001904"
     CDS             12074..12529
                     /locus_tag="KRM55_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH1594150.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSSLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            12578..13162
                     /locus_tag="KRM55_001905"
     CDS             12578..13162
                     /locus_tag="KRM55_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBH1594151.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSCVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(13167..13490)
                     /locus_tag="KRM55_001906"
     CDS             complement(13167..13490)
                     /locus_tag="KRM55_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594152.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            13642..14160
                     /locus_tag="KRM55_001907"
     CDS             13642..14160
                     /locus_tag="KRM55_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1594153.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(14337..15005)
                     /locus_tag="KRM55_001908"
     CDS             complement(14337..15005)
                     /locus_tag="KRM55_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBH1594154.1"
                     /translation="MLEVSHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            15120..16535
                     /locus_tag="KRM55_001909"
     CDS             15120..16535
                     /locus_tag="KRM55_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1594155.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            16758..17216
                     /locus_tag="KRM55_001910"
     CDS             16758..17216
                     /locus_tag="KRM55_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594156.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            17213..17797
                     /gene="clpP"
                     /locus_tag="KRM55_001911"
     CDS             17213..17797
                     /gene="clpP"
                     /locus_tag="KRM55_001911"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH1594157.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            18109..19185
                     /locus_tag="KRM55_001912"
     CDS             18109..19185
                     /locus_tag="KRM55_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1594158.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            19252..21315
                     /gene="bclA3"
                     /locus_tag="KRM55_001913"
     CDS             19252..21315
                     /gene="bclA3"
                     /locus_tag="KRM55_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBH1594159.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGPTGATGI
                     GITGATGLIGPTGATGTPGATGPTGATGPTGVGVTGATGATGATGADGATGVTGPTGA
                     TGATGANGLVGPTGATGAAGTPGATGPTGATGPTGVGITGATGATGATGPTGADGATG
                     PTGATGNTGADGVAGPTGATGATGNTGADGATGPTGATGATGADGATGPTGATGATGV
                     AGATGATGPTGATGATGADGATGPTGATGATGADGATGPTGATGATGVTGATGPTGPT
                     GATGATGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAA
                     GTLTNFAFSMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGA
                     TVTLAPPLTGILSVGSISSGIVTGLNIAATAQTRFLLVFTATASGLSLVNTVAGYASA
                     GIAIN"
     gene            21484..22245
                     /locus_tag="KRM55_001914"
     CDS             21484..22245
                     /locus_tag="KRM55_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH1594160.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            22554..22832
                     /locus_tag="KRM55_001915"
     CDS             22554..22832
                     /locus_tag="KRM55_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594161.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            23125..23700
                     /locus_tag="KRM55_001916"
     CDS             23125..23700
                     /locus_tag="KRM55_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBH1594162.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            24139..24849
                     /locus_tag="KRM55_001917"
     CDS             24139..24849
                     /locus_tag="KRM55_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594163.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            24843..26159
                     /locus_tag="KRM55_001918"
     CDS             24843..26159
                     /locus_tag="KRM55_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1594164.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            26171..26311
                     /locus_tag="KRM55_001919"
     CDS             26171..26311
                     /locus_tag="KRM55_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH1594165.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            26370..26951
                     /locus_tag="KRM55_001920"
     CDS             26370..26951
                     /locus_tag="KRM55_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH1594166.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            27098..28807
                     /locus_tag="KRM55_001921"
     CDS             27098..28807
                     /locus_tag="KRM55_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594167.1"
                     /translation="MSSIKVISDFITKIIRKNILFAITIIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTKMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKVNSENIKFNKKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSYMAYKINLSSKSNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            28822..29694
                     /locus_tag="KRM55_001922"
     CDS             28822..29694
                     /locus_tag="KRM55_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1594168.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            29695..30483
                     /locus_tag="KRM55_001923"
     CDS             29695..30483
                     /locus_tag="KRM55_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594169.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(30579..31217)
                     /locus_tag="KRM55_001924"
     CDS             complement(30579..31217)
                     /locus_tag="KRM55_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBH1594170.1"
                     /translation="MIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGYASDIRMQ
                     KTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLNKESKLDK
                     AVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRAKKDNRFL
                     EALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLEK"
     gene            complement(31244..31873)
                     /locus_tag="KRM55_001925"
     CDS             complement(31244..31873)
                     /locus_tag="KRM55_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBH1594171.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMI
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
BASE COUNT        12207 a         3627 c         5136 g        10958 t
ORIGIN      
        1 acctataaaa ctattaacta atatttgtaa atgtatactt ttgatgataa aatataatta
       61 agttaagttg gtttttataa acataaattt attttaagga ggtgaaataa atgaaaatat
      121 ctagtcaata tagaagtcaa tattcattta gatatgaaag taatataaat aatacaagaa
      181 taaatgaaag tatggttaag aaaaatgaaa ctgtaggaaa agacacttat ttatctaata
      241 ttatgaaaca aaagcaagaa cttaatgata gaattagaga tttaaaatat agacaagagg
      301 tttatactaa aaaaataaat gacgcaatta agaacttatg taaatcagaa ataagagaaa
      361 caactaataa tttttctaat atagaaatag gtattaaaaa tagcattata gaagagaaaa
      421 ataaaagtac aatgttagat gaaaattcaa cttatctaaa tacaaatgat gaaaaagaat
      481 ctttaatcac taaagagtct aatgaaaaaa ttgaagaaga aatattaaat gatgaaaaat
      541 tagaagagtt agaacaaaaa aaggattata aagaggattc taataaaaaa gagaaagtat
      601 ctgaggactt atctttagta ggtaaaactc gtgaagagct tgaaaatatg cttaaaaatt
      661 ttataaattt aacacaagaa gaaataatga aacttgagtc gagaatagaa aagttagata
      721 aaaatgctga agaatacaaa caaaattcaa agactaatat atttgataaa acagatgaac
      781 aaaaaaaaca tataaatgta ctgatttaaa caatatgttt taaaaaaata agtttattat
      841 ataatgaaaa tataaaggta caatttcaat acacttctat taaaccaata atttatgaat
      901 cagatttaat ttcaatttac taataaccat atatttatga gttaatagtt ttatgtttta
      961 aaaagaatta aataaggggg agtagtatga agaagaatat attaactact atgattacca
     1021 tgattattat attgatgatg agtatgacag taatggcaga gccatatcaa gaagatgaaa
     1081 catctagctt gaaaaaacag agtgcaaatg aacgtaatca gactaatata ggcacaatgg
     1141 atggcagagt gcaaacaaat gcaataagta aaggtgctaa ttatgaccct aaatatcctc
     1201 ttaaaggaat gttaacacaa cttggtctta atacaacagg taaagaggga tgggatttac
     1261 tctatggagg aaatcccaat ggagttgagc ttcgagcaga tggtaaatat tattatataa
     1321 ataagggtat ggaagggcta ggattttatg cggcagcatt gtcaggtggc tcatatcaga
     1381 gaataggctt tggaaaactt gaccctatag aagtaatagc tgatggaaat tggatttctt
     1441 acaaacaagc tcaagataca cttacagtaa tcaggaattt tttaaatagc tttgactgga
     1501 gaaatgcatc tgagatggaa agagctaata gagctgcaaa attggtaacc gaagcaaaat
     1561 atgcagactc taaatattgt aacatagtct atggtaatct ggttgataaa cgtggtgtat
     1621 gtggaagttt tgcaagtagc tttcatttat taacaaggtt aatgggaatg gattcactat
     1681 ctatattaaa tccatcatta aatcatgctt ggaactatat acaaattgat gggaaatggt
     1741 ataggtttga tgggtctgaa atatcagctt ttggtggatc attagacttt gattaccgta
     1801 aattaaagga tgcaacaaga gagatgacta cttactatga tgctaaggca ttgtctatat
     1861 taggatttaa tcaataaaaa tagggggagg cttcttatag agcctttttt tattgatttg
     1921 aaatttaata aggaatttta tatgaaaatt taatcaataa aagcaaaaaa ggctctttat
     1981 aaagcctttc taagtgtttt tttaagtaaa attttttata tcaacatcag ttttaatcaa
     2041 aacatataac attttggact tacttttaaa aataaaatta ttaaaatata atattaatca
     2101 tgtttttagt ttattatatt ctataatagt ggtcatgttg actattgtag ttttattaag
     2161 aatagttggt ttatataaat atatgcaaag atagcttgtt gtttacttta cttattagta
     2221 tataggacaa gatactctaa taaatttgcc tattttaata tcttttgtac taaaaccaac
     2281 taaagtttcc tttattattt cgttttgaat aatacaaagc ataatccgat tgtttgtata
     2341 aagactggaa agtatcagag ttattttcta atttagatat acctatagaa caagaattac
     2401 tctctaggca taattctaaa accttctttg ccttattttc aacattctct tttgattgat
     2461 tactatattc aaaaacagca aattcatctc caccaagtct tccaataata gcatcattta
     2521 cgaatacttt agtcaaaata tttgaaaaat gtattagtat ttcatctcct cgaacatgac
     2581 caaagatatc atttacctgt ttaaaattat ctaaatcaaa gatgtaaaag tatccatgtg
     2641 aaacagtttt aagcatttct tttatgtgta cttcaaaaaa atgtctattg tatagtccag
     2701 tcataaggtc tttttctgat tttagtttaa attcatttgc cattgctagt gcttcttgtg
     2761 ctttttcagt tattgtttta gggtaatact catctttcat ttggtcaaag tttggaatag
     2821 aatggtgaac atggataagt ttaatcatat catctgtaac tctgtatacc atagtaaatc
     2881 gagtatccat ttctacatag atatcttttt ctaggtaatc tttttctatt acccaaagag
     2941 taccatatac tataaaagct tcgtctgtga ctttggtaca tgaataccac tcatctataa
     3001 tctcaaagtc tatttgctct gattctgttt ggtctttttc aagacctata ataaattctt
     3061 ctaatgtttc gtaaaattca tgttttcctg ttccaattaa tgcaaggttg tcatctaata
     3121 aggaaataat aaatttaagg ttttcttctt ctggatttaa aatataaata tgccaaattt
     3181 tttttgataa atctcttaat tgtttttgta ttgtattatt ttccatagat taccccctta
     3241 agatttacag tttatatttt aatgtattat aagttgaact cttattacaa tattattata
     3301 atatagaact aaagaaatta catcctgtat aggtaaaagt atatctttta caataaaaat
     3361 attacagtaa aatgaccagt tttaatatac gtattatatt tttaatttat aaacgaatat
     3421 tataaatgaa atttaaattc aaccttgaag aaataagcta aatgtattag tatattaatc
     3481 catgcttgaa cataaataac ctttatgata tgatatcaat aataatatta tgagaggagt
     3541 gccttgatgt cggagttata taatggtaac caacaattaa atagttggag acacatatat
     3601 tctgtataat cagaaatttc aagtgtattt ttaatacatt taatttttgt gtcttattct
     3661 gcctttatag ataactgaca tatgacaaca aatagtattt aaaatatata ttactttgtt
     3721 aaattatggt gtagtaggct ttaatctgct acacttttat taattttgta tagtattatt
     3781 ttgataacta ttttgaaata gagagcatta atttttctag tccacaggag ttttctgttt
     3841 ttgtgctgtt aaatataagc acagaaaaag gcagatatat acctgtggac tttttttata
     3901 taaattatga aatatggagg tagttaaaat gagtataatt gaacttaatg aactgactaa
     3961 atcttataga agatttgaga aaaaggcagg atttatgggg agtgtaaagt ctttatttaa
     4021 taggaaatat acagaaaaaa cagctatatt gtcatttgat ttaaagatag aagaaggaga
     4081 atttgttgga ttaataggtc aaaatggagc tggtaaaact actcttatta agatgttaac
     4141 tggtattatt gcaccgtctt ctggagaaat atctgtaatg ggttattacc ctaacaaatt
     4201 agaaaataat tttaaaaaac aatatgctgt tgttatgggc caaaaaagtc aactattctt
     4261 tgaattgaca ccagcagata cgtttctttt atttaaagaa ttatatgata tatctaatga
     4321 agaatataaa aaaaacttgg attactttat cgaattattt gaggtatctg actatttaaa
     4381 tgttcaagtt aggacgcttt ctttaggaga aagaatgaaa atggaactaa tagtagccct
     4441 tctacataat ccaaaaatat tatttttgga tgaaccaact ataggcttag atgctatagc
     4501 ccaaaaacaa attaggtatt tcctaaaaga agtaaatgaa acaaaaggaa ctactattat
     4561 acttacttct cattacatgg aagatattaa gagtctctgt agtagaagta ttgttgtaga
     4621 aaatagccgt aaaatatatg atggttctac agagaaacta tttaatcatt ttcaaaaata
     4681 taaaaaaata acagttagtt tttccaatga aactaacatt gtatttccaa aagattgtaa
     4741 agttgttgaa caaacaaatc ataagatatc agtaattgtg ccaaaagaaa gaggaaatga
     4801 aacgattaaa tggatttttg ataaatatga tgttaaagat gtaatgattg aagaagaaga
     4861 tataggtagt attgtagaga gaatatataa gaaaggaagt gatgagtatt atgagcaact
     4921 ataatgaagc aagttcaaat gattcaatgt tttataaatt taaacagagt attagaaggt
     4981 attatgaagt agccaaaatt aactttaaag tgcaacttat ctggagattt gatgtggtgg
     5041 ttaatatggt gtttacgatt gtaaaaattt tatttgctta tattttatgg aaagcaattt
     5101 ttggtgaaaa taaaatagtc tctggtttta catttaactc tatgttgtct tactatataa
     5161 taagctcatt tttagcaggt attgatatgt caaagagtac cagtgaagag atatgtaatc
     5221 gtgtaaaatt gggcaccttt tcaaagtaca tgattattcc aattaatgtt caaaattatt
     5281 ttattgctaa aaattttgga atgacatgtt tttattttgt atttaatatg atttctgcat
     5341 ttgtatggat ttttatattt aaaatagatt ttgcctttac atcaaatcca gttcaaatat
     5401 taatttcaat tttgatgatt tttctagggt ttatttttat gatgaaactc cacttcttta
     5461 ttgggatttt gtcatttaaa tttcttgaga ttagtttttt taaaatgata attgaaaata
     5521 ttgttgaatt tattacagga acaatgatac cacttgtact cttaccagaa actatagtaa
     5581 cagttatgaa ggtatttcca ttttattata caacatattt gccatctatg ttactaatag
     5641 gtagaaacag caatgaggca atacaaggat taattattct agcattatgg gttttatttt
     5701 tttctgtagt aaataaagtt atgtataaaa gaatgagaac attatttgat ggggtgggta
     5761 tatgatgaaa aaaaaatttg aaaataatat ttatgttatt aaaaatgaaa ttatcaaaga
     5821 tgatggtatt tagattcgat ttttttggag cattttttgt agatagttca ttatttatat
     5881 tacaacttct aatgtttaat agtatatatt ctcatgtaga ctcaataggg ggatggcaac
     5941 aaggagagat gttaatattt ataggaactt tctcattaat aaatgcgata aatatgacga
     6001 ttttcttttt tggtatttat gatattccac gaaaaatcca agaaggagaa ttagactact
     6061 atattacaaa accattagac ccactattta ggttaacatt tgaaaatatt aatattggtt
     6121 catcaccatt aattctagca agtatactta ttgttttata tggaatatct gagttaaact
     6181 cagagataac tttagttatg ataataatat atattttcat ggtgttattg atgacattac
     6241 ttttttatga tgtatgtatc atacttagaa cagtttcatt ttttgttata tcatcttctg
     6301 cgataatgag attagaagat aatttattgc caatgaatat gaaaattcct ggtgtaatat
     6361 atgaaggtgt ttttaaagta ttattctatt taatcttacc atatggaatt atgtcgacaa
     6421 ttccgactca aattttggct gggacaataa caattaatgg attaatatac tcaattttaa
     6481 ttgtattttt gtttacattg tttatgtgga gattttggaa gttaggtatg agacattata
     6541 aaagtgcaag tagttaataa attagtaaaa atagacaatg tataactata tataaatacg
     6601 tttcatatga cactaaacta tgtgaacaag tatttgcgct aaaggcactg aaagctataa
     6661 aatgattaaa gtaaggattt aaaagtttct ttagtagaaa tataattgtg taaaaaagca
     6721 agattaatta aaactatatc caaataatta gatataattc ttatgcagaa agaaggtctg
     6781 taaatgtcta attgtttgga atatatttta aaaataatta atgtacagaa aaataaacaa
     6841 aatgagtgat gtatattatt cagaaaatca tgaacaagat aatctttatg agcaagataa
     6901 tttactggca caaagattta atttatttac tctattgaag tttgcatttc ctactatttt
     6961 tatgatgatt tttatggggt tgtatacaat cgtagatact atatttgtat caagatttat
     7021 taatacaaat gctctatcag caattaatat tgtatgtcca attattaatc ttatagttgg
     7081 aattggaact atgcttgcca ctggaggaag tgctattgta gcacgtaaga tgggaaatgg
     7141 tgatattgag ggagcaaata aagctttttc tttaatcgta ttatcaggag ttgtaattgg
     7201 ggtaataatt actggtatag gtattgtatt tatggattat atcattatat ggttaggagc
     7261 aagtgaagtt ttaattaaat attgtcgttc atatcttttt attatcttgg tttttgcttc
     7321 tgcaaatata ctacaagtat tatttcaatg tttatttgta acagctggaa agcctcaatt
     7381 tggattatgg ctagtgttag gtgctgggtg tgctaatata attcttgact atgtgttcat
     7441 tgttctgtta caaatgggta ttagtggagc agcacttgca actggagtag gatacctaat
     7501 tcctaccatt tcaggtatgg ttttcttttc aaaaaataaa gggttactta aattttgtat
     7561 acctagacta gataaaagaa tattatttga agcttgtttt aatggttcat ctgaaatggt
     7621 gggtcaacta tcaacagcag ttactacttt tttatttaat gctatgatga tgaaattaat
     7681 tggtgaagat ggggttgcag ctattacaat aattatttat tctcaatttc ttttaacttc
     7741 gctttatata ggtttctcaa tgggtgttgc accaataata agttataact atggaagtga
     7801 aaataatacg cagttaaatc atgtttttaa gatttgtata ttatttattt cagtagcatc
     7861 tttattggta tttatctttt ctatatcatg ttcaccaatc attgtagaga ttttttctca
     7921 aagaggaagc cgagtttatg aaattgcaag gtccggattt tatatatttt cttttagttt
     7981 tattttttgt ggatataata tttttacctc atctatgttt acagcattat caaatggaaa
     8041 ggtgtctgca atattatctt ttctacgtac atttggattt ataactatag gtttattgat
     8101 attgccaaat atattaaata taaatgggat atggttagca gtaccaagtg ctgagatttt
     8161 aaccttattt ttaactattt tttgtatatt taagtataag aatagatata aatatatgta
     8221 gatattaaat aaatagctta gatagatatt ttatgtttta ataagtaatt caattagtgg
     8281 tagatatata ctattgaaaa ttaaagttat aattgatata aagaattaat aaaaataaca
     8341 tataaaagtt taaaagggag ttgaacttaa agtttgatta gaaaaagtca attttaagac
     8401 aactcctttt attttactat tgtattaatc tgtatctgta agtgtattag tctaatatta
     8461 taaactttga atgaaattaa ttttctatag gttttaatgt atcatacact ttattttaaa
     8521 gaaacttatc ttaattttca tagtgattga atttgtctat tagagatgtt actattagta
     8581 atgtaaaagc aagagtagtg aatataaaaa acaagatagt gatactgcaa gattagaata
     8641 taataaattt ttatggagag atttcaatat ggatacatgt tttaataaaa aaatattact
     8701 tgttgatgat gaaaaggata tagtagattt aattgaagaa gtactcataa atgatggttt
     8761 taaaaacatt attaaagctt ataatggtct agatgctatt tcgctctgta agatagcatg
     8821 tccagatgtt gtcattcttg atataatgtt accagatata gatggtatag aagtgtgtaa
     8881 aaaaattcga gagttttcat actgttctat tcttttttta tcatcaaaaa atgatgatat
     8941 tgacaaaata ctaggtctta gtagtggggg agatgactat ataacaaagc cattcagtcc
     9001 aagagaaatt gcttttcgag ttaaagcgca attacgtaga caacagtatc aaagcattgt
     9061 accatcagat agtgaagtta ttaaaatagg agatattact attgatatag aaggaaaccg
     9121 tgtatataaa gatataaatg agattgagtt aactggaagg gagtatcatc ttttaagcta
     9181 catggctcaa aatgtaaata aaattatagg aaaagaaaga ctctatgaac aagtatgggg
     9241 agtatatagt agtatttgtg acaatacaat tatggtgcat atacgacata taagagaaaa
     9301 aattgaagat aacccctcaa atcctaaaat acttataaca gttaaaggac taggatataa
     9361 acttgtgaat agaatcgatt agaatagatt ttaatattaa tgaagatatc tcaagttgaa
     9421 tttttagtta atgaggcatt cttttatggg tgaaatcaaa tgtattttcg ttatctcaac
     9481 aatgaagaag aggtctatct ctattttgag atagcctcat taagtttata tcctggtaat
     9541 gtactttatg ttctaataaa atttttttag tttatttgca gtgaaacatt aactagaaca
     9601 ttaaaatttg cattgaaata ccaattaaat aatattgtat attgtgtata aacttatact
     9661 aattgttttt ctatattaaa tactttatca atccaacctt tataaaattt ttcttcatgg
     9721 gaaactagga ttatacttcc tctaaactgt ttcaaagcat tttgtaaagc atcctttgtc
     9781 tctgcatcaa agtgattggt tggttcatcc agaataagaa aattacaagg agataacatc
     9841 atacaacata atttaacctt agattgttca ccaccactta aagtagatac actccttgaa
     9901 acatgctctt ccttcacacc acatctggct agatgacgtc taatctcttt tgtatttaat
     9961 tttggatatt tatctgctac tatttgaagt ggggttttat caggattttc ccattttaaa
    10021 tcttgctcat aataaccaat tttaacttgt tctgaaaact ggaaatctcc agatatacga
    10081 ggaatatctt ttactaatgt ctttaacaag gtagatttac cgattccatt aaaaccagtt
    10141 ataactattt tttgacctcc atcaacagaa aaatttaatt ttggaagtaa agaatagtag
    10201 tatccaactt caagatttgt tatagtaaga gcattttgag ccgatatttc aatttctgaa
    10261 aattgaatat ttggttttcc tgtaaaacta ggaggagcta ttctttctat tttatccaat
    10321 tgtttttgtc ttcctcttgc aatttttgaa tttactccag ctttattttt acgtataaat
    10381 gtttcttctt tttctatttt cttttgttgt gcttgatacc ttctaatata atcttctctt
    10441 aaatgtgatt tttgtttaag gaactctgaa tattttccat gatatttctt aatcatgcca
    10501 aattctatat caagaatacc tgtagaaatt ttttctaaaa agtcaaaatc gtgggaaact
    10561 acgataaatg ccccattaaa tgtatttaaa taatttgaga gccattcaac atgttcttta
    10621 tctaaaaagt ttgttggttc gtctaataat agaacatcat ggttagaaag tagtaatttt
    10681 gctaaaatta cctttgccct ttgaccccca ctaagctctc caacaacacg attcattcct
    10741 attgaatcta atccaagacc atttgctatt ttatttattt cattatctat agaatagaaa
    10801 ttatttgcta ttagttgttc ctgataatct gatgctttga ttagatattg ctcattttca
    10861 gatatagcac ttttttgata gagtaaattc atttcctttt ctattttata aagttcttca
    10921 aatgcagtgt gtaaatagag tgatattgtt gtatctctat tgatttctgc atattggtct
    10981 aaatggccta tattgatatt aggttgccac ttgatttctc ctgaatctgg aacaacttct
    11041 cccaataaaa ttttaattaa tgtactttta cctgtaccat tttggccaac tacacctata
    11101 tgttcacctt tgaataaatc aaagttagct ttctcataca gtgatttatc cataaaacat
    11161 tgtgataaat tagttacttt taataaactc ataattcaaa ctccttttct tttattaaaa
    11221 aatttatgga aataaaaaaa gcagaggaat ggcattgtaa aatgccgacc tctgcttttg
    11281 gaaaaacaaa aggtcataga caagcattgt tgtctatgac cagaaaatct atattatcta
    11341 tcagcaaata ggtaatttta aataagcata gccaaaaaac tatactaaac ctatatttgc
    11401 cgatgaagat agaaagcttt aagctttcag attaacctct acacaacgct tcatcgtata
    11461 catttgtgta gagttaagtt ttctaacaag tttaactaat tctatataaa tcataattat
    11521 tcacatccta atcttagtat taattctagt ttatctatat ttaaattgta cttttgtact
    11581 ttgtggatta tcttatttat ttaaaatatg ttttattaat tatagcttaa gttatgttat
    11641 cataatactt agttatagtc aataagaaag ttatatttac tattattata ttaatttagt
    11701 aaatctatca ttacaaagtt atttgaagac tcgctatcaa taaaatttta tagtctataa
    11761 gaaaattaag attatgagtt ttataatttt gatataggga tactattttc ataaatatta
    11821 caacatgtag aagtatatgt ctagtattgt tgaattttca atgatatatt aaggttctaa
    11881 tatattatac aaaataaaaa cattaattca acttaaataa ttttaagtat tatatgtgtt
    11941 ttgattaaag aaaactaaaa ttttaaggaa aaataatata tttgtattaa attttattga
    12001 aatgattaaa tttatttact taatgtaaat tattagctaa aattgtatta aataattaag
    12061 gaggtgagta gctctggatg aaatagattt aaaaataatt aattctctaa aaaagaatag
    12121 tagggcttca acctctgaaa taagcagaca aattaattta tcagtaccag cagtctcaga
    12181 gcgtataagg aaaattgagc agtcaaattt aattcaaaag tacactattc aaattaatcg
    12241 ggaaaaaaca aaatataagc ttttggcttt tatatttatc aatactgatt tatctaaaag
    12301 tatgaaagaa tttaagaaaa ctatattgga atatgatact gtattagaat gtcatcatat
    12361 ttcaggagag tatgattact taataaaagt attagcagaa gatacaagta gtcttgaaga
    12421 gtttatatca gtgactttga aggaaattgg ggggattcaa aaagctaata caaccattgt
    12481 tttatctaca attaaagaag aatttaatac aataaaagat attttttaaa taatttacta
    12541 gtaaagtgtt aattatattt taggaggaaa atagaatatg aaagttttag tttttttagc
    12601 aaaaggtttt gaaactatgg aatttagtgt atttgtagat gttatgggat gggctcgtaa
    12661 cgattatggg catgatattg atgtagtgac ttgtggattt aaaaaacaag ttatgagtac
    12721 atttaatata caagtattag ttgataagac gatagaagaa gtatgtgttg atgattatga
    12781 tgctctagct attcctggag gatttgaaga atttggattt tatgatgaag catatgattc
    12841 atctttttta aatctaataa gggagtttaa ttcaaaagaa aaaataatcg cttctatttg
    12901 tgtggcagca ttgccagttg gaaaaagttg tgttttaaaa aatcgtaaag ctactacata
    12961 tcatttgaaa aatggtaaaa gacaaagaca gttaagtgag tttgatgtaa atgtagttaa
    13021 tgaaccaatt gttgtagata aaaatattat aacctcatat tgtccagaaa cagctccaca
    13081 tgtagctttt aagcttttag aaatgttgac atctaaagaa caaatggatg aagttaaatt
    13141 agcaatggga tttaaactgt aatggtttat agattttcta agtaatcaga accccagtca
    13201 cacatggaat ctaaaattgg aataatactc tttccaaaat cagatagcga gtattctact
    13261 tttggaggaa caacaggata aaccactctt ataattaaac catctgattc taattcacgt
    13321 aattgttgag ttaacatctt aggcgttgct ttaggaatta atttttttaa ttcattgaac
    13381 ctcaatatag tgtctttaag atgccaaagt ataagtgtct tatatttacc accaatcaat
    13441 gcaagtgttg cttctattgg gcaactgtaa ttatctaaac attttttcat ttttgggctc
    13501 ctttatttat tttaaagtat ctttttaggt actatattac aaaaaagtgc attattgtaa
    13561 tatagtacca tagtgataaa attatagcat aggttaaata aatcatcaac ttagcctaat
    13621 aaaacaatag gaggtaaata aatgaatttc gttgaacttg caaaaaaaag atattcttgc
    13681 cgtaattatc aagatagaaa ggttgaaaaa gaaaaacttg agaaggtttt agatgttgca
    13741 agaatagctc caactggtgg taatcgtcaa cctcaaagat tgattgttat tcaggaaaaa
    13801 gaaggtataa ataaactttc taaggctgcc aatatatatg atgcgccatt agcaattctt
    13861 gtatgtggag ataaagacaa agtttggaca agaccttttg atgggaaaca acttacagat
    13921 attgacacaa gtatagttac agaccatatg atgttacaag caactgaact tggattggca
    13981 agtgtttggg tgtgctattt taatccagat ataattagag aagagtttag tttgccagat
    14041 aatctagaac caataaatat attattgatg ggatatgaat ctaagatacc agagagccca
    14101 gagagacatg aaaaaactcg tgttccttta agtgaaattg tttcttatga aactctttaa
    14161 ttataaaatt aagttattca ttaggataaa tgtaataaag tgtttattat aaacaaaatt
    14221 caaaataaat aatatctaca tataattaat tttagtgaag tatatctagt ttaactagaa
    14281 tgtatacttc actaatttat ttattcaaaa tatttatgag gattttaata tattaactaa
    14341 aatatatcaa ttgaattaac ttttaaatct ggaaaagcac ttgaaatata gtgttttatg
    14401 tcatttaaat ggtcttgaat ttgcttttct gatattttat caggtccata tacaaaatac
    14461 ataatatttt tagtatcttt tgttatagct gttcgattat cagggccatt aagaatacta
    14521 gataatatac caatattatc tgataaaaat aaatcatctt ttgttaaaat atgttcttta
    14581 ccacctatac cataaaaatg ttcacttcca tttgctaatt ctattttcaa aggtaattcc
    14641 attttatcaa ggtcatgacc tgctgttaga agaagatttt tcaattctgc taaaaacatt
    14701 gactcaattg ttacacctac atctgggata ccttttgatt ttaatagaat agattctaat
    14761 tgaagcaata cagggtaagt tttcttgaat tttttataat actttatata acttgaaaca
    14821 ggctctgttt taattttttc tttgcgattg tattctgggt gttgttctat aatattttta
    14881 attgtagagt ttttaagaac taaaaaattt tctttattag gttttgaatg tgtaatattt
    14941 ataaccataa ctccaaattt aatattggga taaatttctt taactttatg tgatacctct
    15001 aacataatat agactccttt ttattttata ttttatgata taatcttagc aaattaaaag
    15061 tggattttat agttccattt ttatagtaat tttatagaac cacttttgga ggtattagaa
    15121 tgtggattac gattaataga aatagtaata tatcattatc aagacaaatt tattgtgaga
    15181 taaaagatat gattctggat ggaagcttaa agtttgagca aaaactgcca tcatctagga
    15241 ctttatcaaa agaactatct gtatctcgta atacagtttt agatgcatat aatcaattaa
    15301 ttgcagaagg atatttggaa acaaggaatg gatatggaac aattgtagct aaaggaatat
    15361 cagggcataa agttgatttt aagttaaatg atacttttag agatgaaaaa gatttacata
    15421 ctaataaaca aaaaaattat atagattttc gttcaggagt tccagaatta aaactatttc
    15481 cacgcaaaga actttcaaag ctatataaac aaatactgta tgatttatca gattcggatt
    15541 tcagatatgg aagtacagct ggtgtatggg ttttaagagt ggaaatatct aagtatttat
    15601 ttcgtactag aggaattaga tgtaatccca aaaacattat gattgtttct ggttcaacac
    15661 aaggtttatc tttaatttca cagcttttat acaaaagtaa taaaaaggtt gctgtagaag
    15721 accctattca taaaggctta ttaaaggtta tttcatctat tggatattca gttgttggaa
    15781 ttaaagtaga tgataaggga atgaatacca acttaataaa atcaataaag gggatttctt
    15841 ttgtttatac tacaccttct catcaatacc cattaggagg gattttacct attcaaagaa
    15901 gactagagct tattaaatgt gcaacagaga atgattacta tataattgaa gatgattatg
    15961 atagtgaatt tagatatgag ggtcaaccaa ttagttctct ttatgaactt agcccaaata
    16021 aagtaattta cataggttct tttagtaaaa tattatctcc agctattcgt gttggattta
    16081 tgttattacc agacaatatt ttagaaagct ataaaacctt aaaaatgtac tctgatgttc
    16141 atacagaaac aatattgcaa catgtattag ctgaatttat tggaaatgga ggtttagaga
    16201 agtacatatt tagaatgaag aagttgtaca atagaaaacg taagtacctc ataaaagttt
    16261 taaacacgga atttaaaaat gaatttaaaa taaaaggtga agcagcaggg cttcatatag
    16321 ttgctcattt ctataatgtt aaatttacgg aaagtttaat tcataaaatt tttgaagcag
    16381 gtataaaagt ttatcctata caacaatatg caattgagaa tatattagaa tatgaccatg
    16441 aaattatact aggttatgct catcttagtt ttgatgaaat tgaaaaaggt gtaaaaatac
    16501 tcagcaaaat aatacatatg aatcaaggta catagataaa acatgtagca atctacatat
    16561 aatagatgta attaagttta aactttaaaa gaaatatata ttaatatttt tgtataaaaa
    16621 tacctgatat ttttttatcg atactttatt gctatacact aaattaagat agcaatttat
    16681 attaagaaaa aactttttgc ataggttata atacttaaaa ggagaggata gagttgaaaa
    16741 caaatacaga tgttattatg gagataattg attatataga agaaaatctt acagaaaatc
    16801 taaatttaga taaaatagct tatattgcta attattcaaa ataccattta cacagaatgt
    16861 ttacaaatgt tgtaggatgt actatccatc aatacataca gaggaggaga cttactgaag
    16921 cagctagaca acttatattt acagacaaat atattataga catagctatt acagtaggat
    16981 attctacaca tcaatctttt acactagcat ttagaaattt atataaagaa tctccacaag
    17041 tatatagaaa taaagatgaa ttttatccta ttcaacagag atttgtttta aatctaaatc
    17101 atcaaattca aagtgaaaaa tgtatttctt atgcaaatat gaattataaa caaagaagag
    17161 atgaaatcaa ttcttatctt aactttaata ttaattgtga ggtgaaagta gcatgagttt
    17221 agtgccacat gtaattgaac aaacaggtca aggggaaagg tcttatgata tatattcaaa
    17281 attattaaaa gatagaatta tatttatagg agaagaaatt aatgatgcta ttgcaagttt
    17341 agtagtagct caattactgt ttttagaatc agaagaccca gattcagata taattatata
    17401 tataaatagc cctggtggct ctgctacatc aggatttgct atatatgata ctatgaatta
    17461 tgtcagatgt gatgtatcga ctatttgtat tggtatggct gcaagcatga gtgctttttt
    17521 acttgcagga ggaacacatg gaaaaagatg tgctttaccc aattcagaga ttatgattca
    17581 tcagccaatg ggaggagcta aaggtcaagc aacagatgta aaaatagctg tagataatat
    17641 attgaaaata aaagaacgat tagataaaat tctttctgaa aatacaggta aatcaataga
    17701 agatattagg agagatacag atagagataa ttttatgact gcactagagg ctaaagagta
    17761 cgggctgatt gattatataa tgaataggaa tgaataaagt atcaaagtat catattaaaa
    17821 tgtctgtttt acaaatatat atataatatt aaaaaagagt gtctcaaaat gaacttttta
    17881 gtttatggga cactcttttt tgtatgaaat taaatatggt tttatcattt cgacaattat
    17941 taccaaattt caagtttaat aaattctact ataaaaaata cataaaagat aaggttcttt
    18001 agtaactttc tgtcgtcaaa agtttttata aatttaataa caaaacaaga gaaaatacca
    18061 tatattactt atgtctgcaa tatatagaag acaaaggagt tgtacattat gattacaata
    18121 agtttgtgca tgattgttaa gaatgaggaa gaagttatag gcagatgctt agaatgtgta
    18181 aaggatatag tagacgaaat tataattgta gataccggtt ctacagattc cacaaaagaa
    18241 atagtctcaa aatatacaga catggtgtac gatttcgaat ggatagatga tttctctgct
    18301 gcaagaaatt tttcattttc taaagcttct aaagactata ctatgtggct tgatgcagat
    18361 gacataattt tagaagctga tagagaaaaa ttattaaaga ttaaagaaag cttggatact
    18421 tccattgata ttgttatggc aaaatacaat gtatcctttg atgaaaatgg taacccaact
    18481 ctctcatatt atagagaacg attgtttaaa agaagttcta atcataaatg ggttgaccct
    18541 attcatgaag tagtacctct ttttggagag gtattttatt ctgacattgc aatatctcat
    18601 aaaaagcttc atagacagga ccctctaaga aatcttagaa tttttgaaaa aatgatttca
    18661 gaaggaaaaa cattggagcc aagacaccaa ttctattatt ctagagagtt gtactataat
    18721 gctaggtata aagaagcaat agaaggtttt actaagtttt tagactcatc aagaggatgg
    18781 attgaggatt gtatcagtgc ttgcagagat ttagccacat gttattactt aattaatgat
    18841 gaaaaaagtg ccttatattc attgtttaga agtttcgaat ttgatgagcc aagagcagaa
    18901 atttgttgtg acataggaaa gcatatgttt gatagacaaa aatataaaga agccattttt
    18961 tggtataagg tagcattaac aagagataag aatgatacta atggaggctt taagtcaaat
    19021 gattgttatg gatatatacc atctatacaa ttaagtgtct gttatgacag gttaggagaa
    19081 tcagataaag ctatttatta tcatgaaaaa acaaaagaaa tcaaacctaa cgatagtgct
    19141 gttttgcaca atgaaaatta ttttagtaaa tttaaaaata gttgataggt cacaatcata
    19201 ctaaatttga catattatat atagagctta aaagctcaaa tatatcagga ggtgctttta
    19261 ataatgagta gaaataaata ttttggacca tttgatgata atgattacaa caatggctat
    19321 gataaatatg atgattgtaa caatggtcgt gatgattata atagctgtga ttgccatcat
    19381 tgctgtccac catcatgtgt aggtccaaca ggcccaatgg gtccaagagg tagaaccggc
    19441 ccaacaggtc caacgggtcc aacaggtcca ggagtagggg caacaggccc aacaggacca
    19501 accggtccga ctggtccaac aggaaataca gggaatacag gagcaacagg attaagaggt
    19561 ccaacaggag caacaggggc aacaggccca acaggagcga caggagctat agggtttgga
    19621 gtaacaggtc caacaggccc aacaggagcg acaggagcaa caggagcaga tggagtaaca
    19681 ggtccaacag gtccaacggg agcaacagga gcagatggaa taacaggtcc aacaggagca
    19741 acaggggcaa caggatttgg agtaacaggt ccaacaggcc caacaggagc aacaggagta
    19801 ggagtaacag gagcaacagg attaataggt ccaacaggag cgacaggaac acctggagca
    19861 acaggtccaa caggggcaat aggagcaaca ggaataggaa taacaggtcc aacaggagca
    19921 acaggagcaa caggggcaga tggagcaaca ggagtaacag gcccaacagg cccaacaggg
    19981 gcaacaggag cagatggagt aacaggccca acaggagcaa caggagcaac aggaatagga
    20041 ataacaggcc caacaggtcc aacaggagca acaggaatag ggataacagg ggcaacagga
    20101 ttaataggtc caacaggggc aacaggaaca cctggagcaa caggtccaac aggagcaaca
    20161 ggcccaacag gagtaggagt aacaggagca acaggagcaa caggggcaac aggagcagac
    20221 ggagcaacag gagtaacagg tccaacagga gcaacagggg caacaggagc aaatggatta
    20281 gtaggcccaa caggagcaac aggagcagca ggaacacctg gagcaacagg tccaacagga
    20341 gcaacaggcc caacaggagt aggaataaca ggagcaacag gggcaacagg agcgacaggt
    20401 ccaacaggag cagatggagc aacaggtcca acaggagcaa caggaaatac aggagcagat
    20461 ggagtagcag gtccaacagg agcaacagga gcaacaggaa atacaggagc agatggagca
    20521 acaggtccaa caggagcaac aggggcaaca ggagcagatg gagcaacagg tccaacagga
    20581 gcaacaggag caacaggagt ggcaggagca acaggagcaa caggtccaac aggagcaaca
    20641 ggggcaacag gagcagatgg agcaacaggt ccaacaggag caacaggagc aacaggggca
    20701 gatggagcaa caggtccaac aggagcaaca ggggcaacag gagttacagg agcaacaggc
    20761 ccaacaggcc caacaggagc aacaggagca acaggtgcta gtgcaataat accttttgca
    20821 tcaggtatac cactatcact tacaactata gctggaggat tagtaggtac acctggattt
    20881 gttggatttg gtagttcagc tccaggatta agtatagttg gtggagtaat agaccttaca
    20941 aacgcagcag gaacattgac taactttgca ttttcaatgc caagagatgg aacaataaca
    21001 tctatttcag catacttcag tacaacagca gcactttcac ttgttggttc aacaattaca
    21061 attacagcaa cactttacca atctactgca ccaaataact catttacagc tgtaccagga
    21121 gcgacagtta cactagctcc accacttaca ggtatattat cagttggttc aatttctagt
    21181 ggaattgtaa caggattaaa tatagcagca acagcacaaa ctcgattctt actagtattt
    21241 actgcaacag cttcaggtct ttcattagtt aatactgtag caggatatgc aagtgcagga
    21301 attgcaataa attagattag ataagaaaag gcttctaata tcgtattgat attaggagct
    21361 tttttaagaa tgattgatga acatagtttt aatattaatt agtgcgcata ttataaaata
    21421 ctattatata atataaaata ataacattaa attggaaata tagaattatc taggggtgat
    21481 actatgaaaa ataagattga aatatcaatg aacaactttg taaaaaatta tcataaatca
    21541 aataatataa ctacaaagtg gcaagaactt ttgtttgctt atgcatctgc tgaagatgat
    21601 atgtttcaga agctaaaaag tgttgtagga acatctcatg ctatgccaaa agattttctg
    21661 gaaaatggaa aaactataat tacatatttt ataccttttg atgaaagtgt aaataatagt
    21721 aatattggag ggtttgaatg ttctgaaata tgggcaagag cgtacataga aactaatatg
    21781 ttgatttcaa atttaaatga tttcttatgt gaagaactag agaagatagg ggctaattca
    21841 tatgctattc ctgggtcgta taattttgac agtgaaaaat tggtaagtga ctggtcacaa
    21901 agacatgtag cattcatagc aggtcttgga acttttggtt taaataatat gcttattaca
    21961 gaaaaagggt gttgtggaag aataggaagc ataatcacaa gtttagaatt agagccaact
    22021 aaaagaccag aaaatgaata ctgcttgtat aaacataata atagttgcaa aaaatgtgtc
    22081 aataaatgcg tgaaagaagc tttaaaagaa gatggattta ataggaataa gtgttatgaa
    22141 atgtgtatga taaatgaaaa aaaatacact tatataggtg gatgtgatat ttgtggaaag
    22201 tgtatagttg gagttccttg ttcagtaata aacccatcaa gataatggat ttaagttgac
    22261 taataatttt aaagatagtt tataatgaaa aaattttagt tatcaaaata aatataatat
    22321 aaaaactaaa taaatgtgtt taaaaaatgg ataaataatt tgtgttgatt gacaaccagt
    22381 tatactgttg atagacttat atgtatcgct gtgatatata aggagggttg agattttatg
    22441 tttgatttaa tctttatttt tgcatagcaa gggctattgc aactatgaaa tttaatatat
    22501 aaatagccct ttgctattcc taatgaaaaa ttactattta ataggagagc aaaatgagct
    22561 ataaaaaagc aatacatata ttaccagaag aattacttga attaatacag gaatatgtag
    22621 atggtgaatg tatctatatt cctagaaaat ctaataataa aaaagaatgg ggaagtaata
    22681 cacctactcg tgaagagttg tcaattagaa atatgcagat ttacgaagac tatcaagttg
    22741 gatatgattt gcaatattta tcggaaaagt attatttatc tttgaaaagt atccaaagaa
    22801 ttgtattaca agaaaaaaga aaagatatct aaggatgagc cagtatagtt ttataattat
    22861 actggctcat tttcttttga taaaagtgtt tgaggtatag tttcttttaa gtggatgata
    22921 taatttaagt aatttcaata acttatacag tagctaacaa agctggttgt aaagtatcta
    22981 ataagaagta gtagcttttt atatgtttga aattaaaatt tattaaaatt aggaggtctt
    23041 gttttgaaaa aaatacttga ttatattcca ccttttcata actttctatt aatttagtaa
    23101 tcttatagaa aggaaattgt atttatgaaa aaaattactt gggaggtgga atatatctcc
    23161 cagttacctg taattaggta ttgtaaaaaa tgtggaaaaa agactgaata tatttgttca
    23221 ggtttattta gggttaatgc tcaacataaa tatttggata tatggttaat atacaagtgt
    23281 tcaaattgtg attcaacatg gaactcaact atatattctc gtgttaatcc aaaaagctta
    23341 aatccagaaa tactagaaca attccataca aacgattata atcttgttaa gcaatatgct
    23401 atgaatatgg aacttttaca tagaaatgga gcagaagttg gtattccaga gtataaaata
    23461 gtaggacaag aaattaatat taatgacctt acacaagttc atattattag taaatatcca
    23521 tgtcagttaa aggtatcaac attattacgt gagaaactag gtttatctag gaaggtattt
    23581 gacgaaatgt tggattgtgg gattattaga agtaactcag gagttgattt aaagaaaggt
    23641 aaattaaatt atgaaattat gttagatata ggcaaggaga agcaaaagtc ttcaaattga
    23701 ttagaataac taacttaata tattttcagg aacatcattt aaaaaaatag tggctttaaa
    23761 aaatttaaag ccactatttt ttaatatgtt ttatattaat atttaaaata tagtgtgtat
    23821 tcttcaaaat tatagcgata attaaaatat tactataaaa aggaaggtgc atacttttta
    23881 tttaacaaaa actagatatt aaaaactttt cgaggaatat tttattaaaa tccctaaata
    23941 tatttaatat atattaaaaa attgtattat aatgaaaatc aaaatagatt gcaaatccaa
    24001 aaagtaatac ttaatgtcca aaaagctaaa attaaaatct aaatagctat ttactacaga
    24061 agtatgttaa aatatgtaaa atgaatagaa atttatatat ttttattaaa aatatataag
    24121 aaaggatgtt taagaattgt gattaatata ggaatatgtg atgatgaact acattatcga
    24181 ataaaaataa aagatatatt aagtgaaata ttaagttcat atcctataaa ttataacata
    24241 tatgaatttt cagcaggaga agagttacta aataactatc ctaaagattt agacatatta
    24301 attatggaca tacaaatgaa aacaataaat ggtatggata ctgctaggaa gataagagag
    24361 tttgatcata agttagaaat aatatttgtt acttcatttg tagagtttat gcaagaaggt
    24421 tatgaggtaa aagcatacag atatatacta aagccaataa ataaagaaaa aatttctaaa
    24481 agtgtattac cttgtataaa tgagatgatg aaaaagagaa ataattactt aactataaat
    24541 gtaaaaaatt atgtagaccg aattaaaata gattctatta cttatataga aacagataga
    24601 ccgaatatat tgatttatac acatgatgat atgtatatta ctaaaatgag tatatctaaa
    24661 atagaaaaga tattaaatga atatggattt tttagatgtc ataatagcta tatagttaac
    24721 ttaaaattag tagaatcaat gagtggaagt actgttatag tagatggaaa aagtattcca
    24781 ataagtaaat atagggttaa aggcttgaag cttgcgataa ctaatatatt aggggacata
    24841 gtatgctaac aaatttaagt gtaggatttt ggaatattat taatttagtt tcaggtacta
    24901 tagattggat tatatttttt ttagtaatcc acttagttgg aaagaggaaa atatctaata
    24961 taagatatat atttacaaca ataattataa ttatatttat ggcatacata aatgtagtta
    25021 aagtgtttcc aaatattaag attcttctat gtatggtaat aggaatatca ttttatataa
    25081 catcatatga agataaaatc tataaaagta taatagttag tttattgttt tggctaggat
    25141 taatggttgc tgaaggttct gcagtaggtc tagtagtatt tataaataaa ttaaataata
    25201 ttaacataac acaacatgaa aacttattta gaatacaagc tattattatg tcaaaggtat
    25261 ttttatttat aggttttata ttgtttaagt attttaaatt atctttagat tttaaaccta
    25321 aagatatgat actaatagga atacctatat tatctaatat agttagctta ttacttatat
    25381 ttgaatataa tttaagagtc aatacaatta ctacagaaaa cttatttata tttatatttg
    25441 caattttatt gattttatca tcaagtataa tacttttaat agtaataggg aaaattgtac
    25501 aagacgataa attaaatcta gagtatgaac ttataaatga aagaataaaa acaaactaca
    25561 ggaattatga aaatataaac gaagttcatg atagattaaa atatgtttat catgacttga
    25621 aaaaccatat gatttgtata aaaaattatg acactaaaga agaaattata tcatatataa
    25681 ataacttaga gtttcagata agtgaatttg aacattttaa aaatactgga aataaaacat
    25741 tagatttaat tttagcagaa aaaataagta tttgtaaaaa gtatgatatt caaattgaag
    25801 ataacataaa tatatctaaa ttaaacttta ttaaaaataa tgatatatgt tcaatatttg
    25861 caaattcact agataatgca attgaagcat gtatggatat aaataatgag atagaaaaaa
    25921 gaatagaagt taaagctaca tatataaata aatttgcaat aataaaattt ataaatacta
    25981 aggtaaatga tattaaactt attgataaac gtattcaaac tagtaaggat gatgataaga
    26041 tacatggaat aggacttgct agtattaaat atatagtaaa taaatatggt ggtgaaacaa
    26101 tagttaatta ctcagataat gagtttatat taaaaataat gataccaata aaaagttagg
    26161 agagtacaaa atgaaaaaaa tagcgttaaa cttacttaaa aacatctcag cattaagttt
    26221 tgggatagct gtattatcag caaacagtgc aagttcttgg gtagcacatc aggcaaaaga
    26281 gccacaagct ttacaaaaac taaaaaaata acattaataa aaggacctct tcttattaaa
    26341 ggagaggttt tacatgttga ggaggaaata tgtttaaaag attatcatat aaatttgcca
    26401 atatattagt taataatgag attgtagaaa gtgaagattt tgaaatatat agatatggat
    26461 ttgaaacttt gatttatttc atagttaata ttttggtagc attatttata ggaattattt
    26521 ttgatagatt tatacataca gttatatttt taagttgtta ttgcacttta agacagttca
    26581 caggaggtta tcatgctagg aattataaag agtgtacatt aacatttgca gttatttatt
    26641 tgataactat tttttcagct aataatatag atataaataa atataagtat ttattagtat
    26701 tattaatgat tattagtata ctaacaattt acaagttagc tcctttagaa catagaaaca
    26761 aacctcttag tgaaagtgag aaaaagcatt atagaaagac tgtgcaaaaa atactattcg
    26821 taataatatg tttaattatt ttatgtaaaa tacttaatat ttttcagcaa tatgtgattt
    26881 atgcaataat ttctatatat tggattgcta tattaatata tattggaatg aaggttaata
    26941 gtgatcagta agattataaa acattttcta aattaattaa cttcactaat taatattaac
    27001 tttaaaaaaa taatgtcaag gtaagtattt gaacttatta aatatagttg aatctattgt
    27061 aggttgtatc aaaagactgg ctaggagggg cataaatatg agtagtatta aggttatatc
    27121 agactttata accaaaataa ttagaaaaaa tattttattt gcaataacaa ttattattat
    27181 aaattaccat ctcatacaac gatggacaca tatatccaat agaggaattt catttaatga
    27241 ttacttatcc ttgagtgtat atacttgtat gacaattagt attttaacca tgttaaatgt
    27301 aattttttat atgagaaaaa gttatgatac tgtaaaaata ttatgtagaa ataattttga
    27361 ttatttttta ggtatttctg ttgctgtaac tagaaacaac tttatatttt gttgcatacc
    27421 aattatatat gctatagcat actcaagttt aataagaaca ttgtcaattg taacgattaa
    27481 atcaactata tttatattga tatttgaatg gtttttacca cttactattt tatctatagt
    27541 gatatcattt atttcagtta ttataaataa tttaatacta aagattacct tatcatcagt
    27601 atttttatat ttaacatcaa ctaagatgtt ggatagagtt attgatatta aagaaccatt
    27661 ttttaaagca ttatttaaat cacttaacat atttgaagat caatcatatg cttactattc
    27721 tgattttgta gggaaagtta ataattcagc atatgttata gataaaatta tacctacact
    27781 atttgcaatt actttaataa tagtagcata tctgatatta aatgatatta gaaagaaaca
    27841 gattaaatca ttaatagtta tagtagtgta cagtatttta tttattggat taaattatat
    27901 atcaatagat atgtcaacat atagagatga ggagcgtagt tatggagagt atttaaagaa
    27961 atctaatatt agtgatatta aaataaaatc gcatgatatg aagattgact ttaaaagcaa
    28021 gtcaaatata aaagatagaa ttgttttatt aaacacatca aatgaagagt taacaaatat
    28081 taatatgatt ttagatgaaa tatttgatat aaaatatata aaagtaaatt cggaaaatat
    28141 aaaatttaac aaaaaaaagg atttaattga agttaattta aaggaaagtt tagagcctaa
    28201 tgacgaggtg acattagata tagagtatga aggctatatt aatgtgttga catcttggaa
    28261 tcaaaataaa tatatagcta ctaaagatga tattatgctt ccaccaggtt ctttagcgtg
    28321 gtacccaaaa gtaaatcaat caagttatat ggcttataaa ataaatttaa gttctaaaag
    28381 taatgtctat tcaaatttac ctttactgaa taagactagt aattttttaa aaaaagatta
    28441 tatatttgaa ggaaagtcaa atgatattgc aatatatgca ggtgagttta aagaagaggt
    28501 aaaagatgat ataaaaataa tctatccatc agatagtaat gtaaatatgg atatagagga
    28561 aaaaattaaa tttttaattg aaacaagaaa tgaaatatta ggtgatagca aagcatctgt
    28621 agatgctaaa aaatatgtag atgaagtaga taatgttatg gaatcaataa aaagaaaaaa
    28681 aattaatatg atattagttg ctgacttacc tagcaatgaa tttttatatg aagactcaaa
    28741 gggagagaaa attagcataa ctatttatca ttggctttca ggaaatatcc ttataataga
    28801 taaataataa aggaggttaa tatgataaac aagttagaaa taagaaatct aaattttaat
    28861 tacaaaaata aaaaagcttt ggataatata aatttaaccc taacagatgg agtagttgca
    28921 ttattaggtc ctaatggtgc tggaaaatca acattaatga ggttattagt gactctttat
    28981 gaaacttcaa ttggagagat agaattaaat aatataaagt atagcaaaaa caatgagaaa
    29041 atcaaggcaa atgtaggata tgtacctcaa gattttgata tgtataataa tataaatggg
    29101 caagaatact tagaatttgt agctaaaatg agaggtgtat ctaagaatga tttaaagaaa
    29161 catatacaaa aagtagtatc aaaagttaat ctggacaagt ttataaataa aaaaataggt
    29221 acatactcag gtggtgtaaa gagacgacta ggtatagcac aggctttaat aggtgattct
    29281 aagttaatag ttatggacga acctacagtt ggtcttgatc cagagcaaag gaatgaattt
    29341 agaagattgt taccagaaat aagtaaaaat tctatagtat taatttcaac tcacatagta
    29401 gaagacatac aatttaactg tgacaaatta attatattaa atcaaggcaa aatattatat
    29461 gatggtacaa ttaataagtt tattgatatg gttgaggtgt attcggtagt agtttctaat
    29521 gatgaatttg aatatttaga acgtaatatt gatattattg attataggag agttaaagat
    29581 ggtgtgcaag taaagtatat aggtaaaaat acagagaaac ttaaagatag cttaaggata
    29641 gatacaactt tacaagatgc ttatataaac tttttacata aggagttaaa ataaatgtgt
    29701 atattggagt taataaaatt tgagcttaaa aaaatagagc ttaaacatgt gttaatattt
    29761 gtaattattt ctatcttatg catatttatt acaggcatat tagattataa tgagttaata
    29821 ttttataatg atgtacctat aatggataca tattctatag caggatggtt aggaattata
    29881 aagatatcag atgtttttat accaataatg tcagcaatca caataattta tgtgttttca
    29941 aaagattatt cgggtaatat aaacgagata cttactttat ataataaaaa aaaatataat
    30001 caatttatag tatttagatg gtgtgttata ttagctatat atactgtatt attattaatt
    30061 tcaattacaa tagtatatac atttacgtca gtgaaaggtt ttaacataga caaaatagat
    30121 tttgtttata gtgtaaagcc aatagatgtg tttttaaaga catttcctac attattatgg
    30181 tatacaacat ttccactaat gatattaaca ttaacaaaaa atagatttac aacaatagca
    30241 atattaatta catatacatt tgctgatata ttttttattt tacatatgta cccatttgtt
    30301 agtatgatta atgtaaatgg attttatatt caaaagatgt tttatatgcc taacaatata
    30361 gatgttagat ttaatgaatt aaagaattat ttctttataa atagaggttc tctagtagtt
    30421 atttctataa taatagtttt ttatatagca agaaaatcaa cggttttaaa aaagagtaaa
    30481 tagtttaata tattttttat attgttatat ttatatagaa tagtgacttt aaaaaattta
    30541 aagccactat tttttaatat gttttatata tataactatt atttttctag gttttttaat
    30601 atttcgtaat agtgtgttgt ggctatttca cttgactcgc cttttttaca aaaagataat
    30661 ttggatagtt ttggaactac acgttcaacg acaattttat tacctatcat tttagattca
    30721 agtatcttca atgcttctaa aaatctatta tccttttttg cacgattata aaatgataaa
    30781 acgtagacat aaaggaatag gttataatta cggaaaggat attcaacttg cataaataat
    30841 gtgccaattc catagtgaca agggccgatt ggttttttaa tagtccaatg gtcaagtaga
    30901 aaatctacag ctttgtcaag ttttgattct ttatttagat aattactaaa acggaatgca
    30961 tttaatatat taagagttgg tagtggattt gagtattcag tttctggacc tcgaccaaaa
    31021 ctaaatttat tgcaacgcca cccaccatca gtatactgtg tatctaaaaa atgttgaaac
    31081 gttttttgca ttctaatgtc agatgcatat cccatatgac agagtacgtt agcagcattt
    31141 gcagtatgac aagggtaaat acctccattt ggatatagtt tgaaacgtcc atcttctcgc
    31201 catgtgctaa atatcaaaaa ctttattata atattattta tatttataat tgatttattt
    31261 tatttaaaat tgcatttata gctgtatcag gaacaactgc taaatcttct gcattgaagt
    31321 aataaactat attagaatca aataatatat ttgaatttgg aggaaattca tcatctccaa
    31381 accaaagtat aaatatcata gatgtattac ccatatatgt aaacctataa gctaaatctc
    31441 ccatgtttac tttttcagct ccaattttct ccataactaa cttatatttg tctatttgag
    31501 atgtaaaaac ttctgaaagc ctatatagag tcctgtttaa aaaatttgga taataaacat
    31561 tgcctcctgg tatttcttta aaagttacat atttattagt tctaggaata cctttagcat
    31621 tgattaaata tctaactatc aagattttaa gctcaaagtt attgcaaagg ctaccattac
    31681 tattccaaac ttctccactt ggatagtcta taatatattg tctatcaaaa aaattgagtg
    31741 tgaatctatt taaatcatta ttgaaaggta tattacttaa attactaatt gtatgagggt
    31801 ctaattcttt gagttttttt cgaacatagt caaatggaac attataatta ttttttgtta
    31861 tcttttcatc cataattttt tcctccaatt taaacaatta aaagtattaa aaagttttct
    31921 tattatta
//
LOCUS       DAEPXW010000042        31273 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.043, whole genome shotgun sequence.
ACCESSION   DAEPXW010000042 DAEPXW010000000
VERSION     DAEPXW010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.043"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            394..2628
                     /locus_tag="KRM55_001926"
     CDS             394..2628
                     /locus_tag="KRM55_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1594172.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQYIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLAMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2659..3504
                     /locus_tag="KRM55_001927"
     CDS             2659..3504
                     /locus_tag="KRM55_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1594173.1"
                     /translation="MFKEIFLKTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFMDSHNIQLDWEKNYPYDKISNWIFEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            3744..5477
                     /locus_tag="KRM55_001928"
     CDS             3744..5477
                     /locus_tag="KRM55_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1594174.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5803..6491
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5869..5897
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(7021..7125)
                     /locus_tag="KRM55_001929"
     CDS             complement(7021..7125)
                     /locus_tag="KRM55_001929"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH1594175.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7750..7995
                     /locus_tag="KRM55_001930"
     CDS             7750..7995
                     /locus_tag="KRM55_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594176.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIVFANCIMFSNILLEIFLIYICRKFRKI"
     gene            complement(8748..8894)
                     /locus_tag="KRM55_001931"
     CDS             complement(8748..8894)
                     /locus_tag="KRM55_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594177.1"
                     /translation="MVFETFDKTIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            8990..9639
                     /locus_tag="KRM55_001932"
                     /pseudo
     CDS             8990..9639
                     /locus_tag="KRM55_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
     gene            10181..11536
                     /locus_tag="KRM55_001933"
     CDS             10181..11536
                     /locus_tag="KRM55_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1594178.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(11654..12322)
                     /locus_tag="KRM55_001934"
     CDS             complement(11654..12322)
                     /locus_tag="KRM55_001934"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBH1594179.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREELVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(12389..12817)
                     /locus_tag="KRM55_001935"
     CDS             complement(12389..12817)
                     /locus_tag="KRM55_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH1594180.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            12924..13517
                     /locus_tag="KRM55_001936"
     CDS             12924..13517
                     /locus_tag="KRM55_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBH1594181.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            13636..14571
                     /locus_tag="KRM55_001937"
     CDS             13636..14571
                     /locus_tag="KRM55_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBH1594182.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(14842..15786)
                     /locus_tag="KRM55_001938"
     CDS             complement(14842..15786)
                     /locus_tag="KRM55_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH1594183.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKINKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKLCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            16104..17534
                     /locus_tag="KRM55_001939"
     CDS             16104..17534
                     /locus_tag="KRM55_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1594184.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGHLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            17734..18318
                     /locus_tag="KRM55_001940"
     CDS             17734..18318
                     /locus_tag="KRM55_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBH1594185.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(18422..19201)
                     /locus_tag="KRM55_001941"
     CDS             complement(18422..19201)
                     /locus_tag="KRM55_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1594186.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(19259..20515)
                     /locus_tag="KRM55_001942"
     CDS             complement(19259..20515)
                     /locus_tag="KRM55_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBH1594187.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            20773..21672
                     /locus_tag="KRM55_001943"
     CDS             20773..21672
                     /locus_tag="KRM55_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBH1594188.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            21696..23144
                     /gene="ddlR"
                     /locus_tag="KRM55_001944"
     CDS             21696..23144
                     /gene="ddlR"
                     /locus_tag="KRM55_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBH1594189.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFENIEIGIKIIGETINEMF"
     gene            23203..24009
                     /locus_tag="KRM55_001945"
     CDS             23203..24009
                     /locus_tag="KRM55_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1594190.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            24035..25954
                     /locus_tag="KRM55_001946"
     CDS             24035..25954
                     /locus_tag="KRM55_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1594191.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTPKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(26196..26543)
                     /locus_tag="KRM55_001947"
     CDS             complement(26196..26543)
                     /locus_tag="KRM55_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBH1594192.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(26530..28458)
                     /locus_tag="KRM55_001948"
     CDS             complement(26530..28458)
                     /locus_tag="KRM55_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBH1594193.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(28869..31058)
                     /locus_tag="KRM55_001949"
     CDS             complement(28869..31058)
                     /locus_tag="KRM55_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBH1594194.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEIPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
BASE COUNT        11748 a         4405 c         3982 g        11138 t
ORIGIN      
        1 atatggtatt aaattatgta taaaaagtta attatgaata aaataattat gcctttgaaa
       61 aatcattaaa cttaaaatta attataaaaa aactctacct tactaactat acagctcaca
      121 atctatctat ttatgaaaaa atatgatata attgcattca aaaaggaaat ctttcaatat
      181 actagaattt aagcattaac taattttatc taatattatt actaaactaa aaaatatttg
      241 tatttgtagc attggagcaa gtaacttaat gtatattcat tttaaatact tatttaaaat
      301 ttagcattta aattatttac aaattaacat ttaaatactt ctagcataaa tacagttatc
      361 atcaaaattt aaagtatctt atggaggaat accatgcaaa atcataatta tataaaaatg
      421 ttaaataaaa aggtagaagt attatctaag gaattagata gtagaaattt taaattaaaa
      481 accttaaatg aaatagattt tttttctaaa ataccaaaca gagaatttat gtaccaatat
      541 attgatgact gtatttcgaa aaatatacat ataggaatca tgttattaaa tatcgataac
      601 tttaaattat ttaatgatat atatggatat ctagtcggag aaaatttatt aattactcta
      661 actcaaaacc ttttgcactt tattccagaa tcaaagggaa tagtcgctta tttaaaagga
      721 gaaggttttt taattgtact tccaaatgta tcaaataaag agttaaataa tatgggtgca
      781 actattatag agagcgcccg agaattaaaa ataaaacttc ctaatgaaaa agaaatatac
      841 tccaatgtta catttagtat cggcagcact atctggaatg gtgaaccaaa catgactact
      901 ttgatgcttt tcaaccaagt atatagtgct ttaaaaaagg ctaaaagtga aggtaaaaat
      961 agatacattc tatttgattt taaagataat agtttttaca ataaattaga aaatgataag
     1021 gagttcttat cagaaatatc acatgttcta caaactaaac aaattgaagt attttaccaa
     1081 ccactttata atataaaaaa taatactata gttggatgtg aggcacttgc aagatggaga
     1141 caccctatta aaggacttct tactccagat aaatttattc ctttatttga acagtttggt
     1201 ctgataacgg aattagattt gcatttattt gaagagaact gtaaaaatat aagaagatgg
     1261 attgataaca atgatgtttt tgttccaatt tgttgtaact tttctcgtct tcattttttt
     1321 aaccctaatt ttccaagtat gctaaaaggt attactgaaa agtacagcgt ctctacatca
     1381 aattttagca ttgaaataac agaaaatata ttaatagaaa atacaaatac aattattcaa
     1441 caactagctg aacttcgttc ttatggtttt tctgtatcaa tggacgattt tggttctgga
     1501 tattcatctt ttggtatgtt gcaaaatcta ccttttgata taatcaaaat tgataggata
     1561 tttttatctc ataatttaaa tgattttaaa aatacaacca ttttgtactc tataataaac
     1621 attgcaagag ctcttgggat gcttacagta tgtgaaggtg ttgaaacaga acaacatgta
     1681 gaatttatta aaagtataaa ttgtgatatc gcccaaggtt attattatgc aaaacccatg
     1741 gagtgcaaag aatttgaaaa attactatct aaagagaata attcagagaa aatgtttata
     1801 aaatattctg atataggaaa atctttaata gagaagatat ttgatggatt ttttattatg
     1861 caagatatga aaaaactaag agctaatgtc actgaagaca ttcaatggtt tgatttttac
     1921 aacaaaactg aaattacatc ttttcctaaa gtaatagaac attttgaaaa acatattaaa
     1981 ggtaaaaaat tttctattct ttacaaaagt ataaccccac ataatactga atcagattca
     2041 ttattaatta gtggagaagc cgttttatca gatgaagctt ctgaacatca aaaatatagc
     2101 aatttctact ttagtgcaaa ttgtataatt tcagaaaata aattactctt agcaaaatta
     2161 catttggatt taattaaaac tgctggctat ataaatgaat ttgaatcata ttcaatacct
     2221 aaaatgacaa atacacatct tgatgaaagt aatattttat cacaatttta ttcaatgttg
     2281 cctgtaggta taattcgcta cgatttattt ggtgatatga ttattactta tatgaatgaa
     2341 gaaatgtttg atattatagg ttatacaaaa gaacagtttt ttggtgagat gggcggaaat
     2401 ttaagagcaa ttgttcatcc agatgattta gactttgttt ataaaaaaag tttggctatg
     2461 attgacacaa ataaaattga accattttta tatagattca taaaacgaga tggtcaaatt
     2521 gtcacagtta tgtatacaca atgtaacctt tctgcaattg atggaaggtc gattgcccag
     2581 ggtatgtatg tagatgtaaa taaaataaaa aatttaacaa aaatctagta caaagtattt
     2641 tattttggag aaattaatat gtttaaagaa atttttttaa aaacttttcc aggatttcta
     2701 attataagag attctaacta cagaattata tttataaatg ataatttaaa aaatttaatt
     2761 aaaagttata tgcaagataa tccacttgga atgactaata tagaaatagc taagaaactc
     2821 cctgataata ttgctaaatt ttttatggat tctcacaata ttcaattaga ttgggaaaaa
     2881 aattatcctt atgataaaat ttcaaattgg atttttgagt ttaaaaaaga tactacaagc
     2941 tattggaatg ttttagaata caaagtagat gttgatgaaa aaacctacat aattactatg
     3001 gccaatgata taacaaaact ctatgaagaa aataagagaa atcttcacta ctcaattact
     3061 gacccattaa ctggagcata taatagaaaa tatttaaatg atagatttga catatttata
     3121 ggagattata ttgtactaat tgacttagat aatttcaaaa tgataaatga ctatgaaggt
     3181 cataatgtag gagacaagat tttatgtgat tttgtttcac ttttaaataa agaattaata
     3241 aattctactt ctattataag attaggagga gatgaattta ttgttatatt ctctagtgat
     3301 gttgacaaaa attatgttta ttcacaacta gaagccttaa gagaaaattt tttaaaagta
     3361 ttctctaagt ataagtatct ttcatttagt tatggtgttg atacagtaaa aagaaattta
     3421 aaactgacaa tagttgaatt ggataaaaaa atgtataaaa acaaggagaa aaacaagaaa
     3481 aaatttgata aaaatgatta ttaatattgt tattttaaaa taaattaaaa ttatctttct
     3541 ttttttaaac ttgtacatta gtttataaat atgtatctat acaagatatt gacattaagt
     3601 actgaagcat atattgtttc agttcttttt tgttaaaatt aacttatttg acaaagatat
     3661 catagtttaa caaagctttt aatttaaata tattgatgta taatataatt aaaatataat
     3721 agcaaaaaga aaggaggaat atcatgagca tactcctaaa aaaagcaccc aaattagcaa
     3781 aacatattat aacaagtttt tatataaatc gagatatcaa tgaagtatta aaataccttt
     3841 gtgaaaatgt tacatggatt ggaccaggag aacaggaatt tctcacttct tttaatgaaa
     3901 taaaaaatta tttttatgca ggtcaagatg aaattccttc ttgtgatata aataatgata
     3961 tatttgaaac tgtaagtgaa gatgagaata gatgtatggt attaggaaga tatactgttc
     4021 gaactaaaga aaatgctcaa atgattttag aggtaaatca acgttgtaca tttgagataa
     4081 ttgaggatag aggaaaatta ttaataaagc acatgcacat atcaaaccct tatggtgaaa
     4141 tgcaacttga tgaatacttt cccactaaaa ttggaactca aagttatgat tatttgcaaa
     4201 gattactaaa agaaaaaaca gaagttattg aaatgattac aaataatatc aatggtggct
     4261 taaaaggtag caatgatgat agtacatact catttttcta tgtcaatgag ggattgccca
     4321 aaatattagg atacacatat gatgagttca tggaaatgag tggtggttca gcagtgggtg
     4381 ctgtatatcc accagactta cctaaagcac tagaagattg tgaacgatgt tttgcaaaag
     4441 gacctacata ttcatctgaa tatagaatcc gaaaaaaaga tggaacatta atgtgggtat
     4501 tagattctgg aatgaaatcg ttaaatagtg atggcatagt caaaattaat agtattatta
     4561 ctgacataac ccaactaaaa aacatagaat ctgaactaaa attagaaaga gagcgatatc
     4621 gtattgcttt gcaaaatatt acagatatca tgtttgagta tgatattgaa aacgataccc
     4681 ttataaaata tcaacgtgta gaaattgaca aaaaaattga attagaaaat tttgaaacaa
     4741 aaaattactc caaactatta gaatctggta aaattattca ccttgatgat attggaaaac
     4801 tactagaagt acttcatgga aatcttcgtg aaacaattga gataagacaa gtaaattcat
     4861 taactaaaaa tgaatggaga tggattcgtg ttcaatgttc agttatatat gatagtgacc
     4921 ataaccctat caaaacaata ggcgttttaa aagacataac tgaagataaa tctaaattag
     4981 aaagcttaat taatcaggct caacgtgacc cactaacaca attatataat caaagagtat
     5041 cacaaaatct tattgaagag tatctatgta gttctgattc caaaaataat gatgctctat
     5101 tagttattga tattgatgat tttaaaactg taaatgatac ttttgggcat ttagagggaa
     5161 atgaagtttt agttgctgta tcaaaaatac tattacataa cacacatgat aaagacatag
     5221 ttgctcgaat tggtggagat gaatttacaa tatttataaa atcattaaca aaggatttaa
     5281 taataaaaat tactaatgat attttaaatg atgcaagtaa aataaaagta aaggacaatc
     5341 ataaaataac attaagtatt ggtattgcct tcactgatga ttcaactaaa ttatataaag
     5401 atttattttc taaagctgat aaagctcttt atctatcaaa agcagatggc aaaaattgtt
     5461 atagtacata cgaatgataa agctatttat acgaccaaga ataaaccttt aaatttaatt
     5521 tcatagtcta acaatcaaag agttgaagct aatcttatag ctagtcaact agttcctaga
     5581 aaaaatttag acaatatatt tattgatact gctcattttt ctaaagagca aatttatata
     5641 aaaaattaaa cttttacgta catacagata ctaatgataa acagttatca ttagtatctt
     5701 ctatcttaaa acaaaatgat aatttatcta tataaaaaag tgctttgttg acagagttca
     5761 cttttttata taggtacaga atttaagtat aaatacatgt tttattctat acattttagt
     5821 taatgtaaaa ttccttgatt gtactctcta acttttcaac attatactat ttacatacca
     5881 cttagttaat ataaaacatg tatttatttg ttcttgtact attgttttac tctatttaca
     5941 taccacttag ttaatataaa acactccaaa acttgattct aaatttagaa aaggactata
     6001 tttacatacc acttagttaa tataaaactg tagaaagctc gtttgtggat gaagttctaa
     6061 aatcatttac ataccactta gttaatataa aactatagta tatcaaaaaa aaagaaatgt
     6121 gtccacaacg atttacatac cacttagtta atataaaaca ctagcttctt ttgctaaagc
     6181 agtttttatt ccaagattta cataccactt agttaatata aaacaataca gttcaaaaag
     6241 tagtgagctg gggaagtcaa aatttacata ccacttagtt aatataaaac gatacctgct
     6301 atcgcaagtg ctaatgctcc aattcctaca tttacatacc acttagttaa tataaaacca
     6361 tacttttaac tacgacttat accctgtact agtgaattta cataccactt agttaatata
     6421 aaacttaaag accattctga attttttatt tatcgtaaaa aaatttacat accacttagt
     6481 taatataaaa ccccaaaata aactgggcat tttcaatact tacacatatg caactctctt
     6541 aaatttgcag tgaaccatga gtagtgcaaa tgataaagct tatcatatac cctcaacacc
     6601 ttatatttca agcgttaagc tctactttgt aacaaatatc gctcactgca aaactattta
     6661 catttttatt atatcataaa tatattattt ttgaatatct ataccaattt gtggtataat
     6721 aaaagcaaga agaactacaa tctatttaga cgtagagtga agttcaaata ctaatgttta
     6781 ttctttttga acttgatttt tagttcaaaa ctaaagtcac tcctgcctgt gtgaactata
     6841 cccgctgttt tatacagtta aaacatgtaa aaatagttat aaagtactag tgtaactcat
     6901 tagtactctt tttattatat tcatataatt aatatctata ttttaaagtt tactatctaa
     6961 aaaagagcac gtcaaataaa accctagata tttaattttt ttagagatac ttaaaataaa
     7021 ttatgctctc tctgtactta aatatttcct aaattcaaat ggagacatag aatttaatct
     7081 attttgatat ctaaaattat tatagtagta tatataatca tctattgctt taactaatta
     7141 ttcatatgta tcaaatttcc ttaaatagta catttctacc tttaaaattc cccaaaatcc
     7201 ttccatagga gcattgtcaa ggcaacgacc aactcttgta taatatatgt atatctaaca
     7261 ccattaagaa atatatattt tataatatat atttcttcat ttaatgcact tagaaaagca
     7321 aagaaaatac agattagtac actttttaga gaaaaataaa attaatacat ctaaaatatt
     7381 aaaaaatact ttagataatc taaagacaca tctcaaagtt tttaactaaa ttataaaact
     7441 aattacaaat gctatgtaac gataataaat aaaaaattta cttcgcttaa gcgacgtgtc
     7501 gttgaaatat ttcatgttgc caactggttc gtaagttgat aagaaaagaa cactaattat
     7561 ttagagttct tttcttagct acaagtggat tataatactt ttaaatctgt gagaaaatca
     7621 tatataataa tgatatgaac aagtaaagaa aatacaaaaa tgacaaaatt ataaataaaa
     7681 tattataaaa tcataaggtc ataattgtta tattgtagaa acaaagtaaa gagagagggt
     7741 ggagaataaa tgaatcaaaa aaaaataaag attagtatta aaatggtaat tataggtata
     7801 tttgctgtaa ttattgcttt tgtattatcc agattattcg ttgagtatat tgatgaatta
     7861 ttaaggtcta attggcaata tcagctattt gaaagtgaga gttcatatat agtatttgcc
     7921 aattgtatta tgttctcgaa tatattatta gaaatatttt taatatatat ttgtagaaaa
     7981 tttagaaaaa tctaatatgg tcaacgtatt tcgaatcgaa tacttcatga ttatttagtc
     8041 tattgtgcta gttaaagttt aattcccata taaagtaaat tgattttagt aaaacaaatc
     8101 acccctaagg gttagtttat ggataagtca tccaaatatt aactctttaa tttttgctat
     8161 agattcatct ttgctcataa ctttacttat aaaaaatgaa atattataag ctagaacttt
     8221 tattctaatt ctagtcataa atcctagcat agagttactt tttttatatt ataaataaaa
     8281 ctatacaaca aagataatat ttagtaaaaa taactttcat tttaactaaa cttaaaattc
     8341 aattactctc taaattgacg tttaggaatt agttcaaaat aaaaaagagt gtatatattg
     8401 aaattactac atttcaatat atacactctt tttaaatttc tcagttttcc atggaacttt
     8461 actttattta tttctgtatt agttgtattt tttatgcatt tttctttaaa atcatatttt
     8521 ctgattcaac tcttatatta taaaatttct ttactaaatt attctctttt tctatatctt
     8581 catatatatt ttttaatcgc cttttaccta atcttttatc taacattact aatgatttaa
     8641 ctaatatatt atatgatttt atcgcatctt ctattgagat atttaaacat atatttactg
     8701 cttcataaaa atcaaattca ttaaaaaatc catttttatt tacaatctta tatccctttg
     8761 catctctttc taaatactct tcctaaatac tcttcaaaac tttcatcatc taatctaaat
     8821 cctatatcac tatgaaaaat aggttttgca tttggatata gttctattgt tttatcaaaa
     8881 gtttcgaata ccaagttatt attattcgat tttccaatag tccactataa acaataataa
     8941 gtttgttgct ccaaataatg taacacttgt agaaagatgt tacagatata taaaagatag
     9001 agaatgtagt ttttctccta atactattag aaatagaaaa aatatgatta aaaatcaaat
     9061 tgaagttttc tttaaagata tgaaattaat agatataact ccttctattt tacagtctta
     9121 tataaataac atatacaatg agcacatgtt aaattcaaca aaaaaccaag tcgattttat
     9181 aaagtcagta ttgaaagaat cttatagatt aaaagaaata tcagaaaata tttgtaattt
     9241 tgttacaacc ccaatcaaaa aaaatagttc aacttctaag ctttatacaa aacaaaaagc
     9301 tcaattatta ttagaaaaat caaaaaatat tcctataggt ataccagttt ttttgatgct
     9361 aactcttgga ttacgttttg gtgaagctgt atcacttata tggtcagatg tagaccttga
     9421 taaaaaatct cacatgtaaa tcaaacatta gtttatgtat acaataaaat aatcttcaaa
     9481 gaccctaaaa cccctatatc caaaagaaaa ttatttgctt ctgatgaact tataagtttg
     9541 cttaaagggg aaaaattaaa acaaaataag ttgaaattac agggtatatt gaaaaatgaa
     9601 tttgatttga tatgcttaaa taaaagattc aacccgtgag ttcaaccaac ttttgttgtt
     9661 cattttaaaa aactattaag agataataat cctagagata taaaagtaca tgaattaata
     9721 catgcaaatg cgactttgat attactttca ggtactaaca taaaagctat ttataaaata
     9781 ttagtacatg cagatataaa aatagctatg aatatatatt ccatattctc acttattaga
     9841 tgaaatgaat aaagaaacat ctgaaaatat aagcaaaata ctattcaaat aatgttcagt
     9901 tttatgtcaa ttaaatgtca ctcaaagtgc tttttttcca tttgtcagtt aaatgtcact
     9961 taaagtacct ttttcctatt tgtcagttaa atgtcagtaa tatataaata agatatattt
    10021 ataagaccct taaaatcact attatttaat aaaatttata attatatact atttgctgtt
    10081 gacattggta ttataccata gtttatcatt tatattagaa ataaaattat taattaatag
    10141 tttcgtaatt ttataataga tttacaggga gtgatagtaa atggatacaa aaatatctat
    10201 aaacgaaaac atgagtctag gtaaaagatt ttttaaatac ctagcaccat ctgtagttgc
    10261 aatgtgggtt ttctcactat atacaatggt tgatggaata tttgtaagta aaggagttgg
    10321 agaattagct ttagctgctg tcaatatatc aatgcctttt attaatttta tatttgcagt
    10381 ttctctatta ttttcaactg gtgcatctac cataattgca atctatctgg ggaaaaaaga
    10441 tattaaatct gctaacgaag tcttttcatt taacttagta tcaataatta tattatcaat
    10501 aattatatta gctataactt tttttaattt agatagatta gcactatttt taggagctac
    10561 agaatctaca attggtatgg ttaaagatta tttaggaata ataatatttt ttaacggatt
    10621 ctttatagtg tcttattctt tagaagttat aataaaaact gatggctttc caatattagc
    10681 tactgttggt gtaataatat ctgctcttac aaacatcata cttgattact tgtttgtaat
    10741 tgaatttgga tggggtgtaa aaggtgctgg tattgcaact ggtttgtctc aagtcttttc
    10801 tactattttc ttcttaatac attttttaag aaaaaactct actttgaatt tttcaaaatt
    10861 tagaattgat tttaagacac ttagaaaaat tgtatttata ggttttcctg attcaactac
    10921 tgaattaagt tgtggtatag ttgttttact ttttaactta agtcttacta aatatattgg
    10981 agaaaatgct cttatttatt atagtgtcat aaattatata aatacattag tacttatgac
    11041 tatgatgggt ataactcaag gtatgcaacc acttactagc ttttattatg gtgcaggaaa
    11101 tatagataat gtaaaaaaat tattaaaaat ggggataaaa gccacaataa tagcatcagt
    11161 tgctgtattt gcaatttgta tggctttttc aggaccaata gtctctttat ttatacatcc
    11221 agaagaaaca atgctattca atgaaggagt tcgtgtattt aaaatattct ctatatcttt
    11281 cttattggta ggaattaatg taataatttc tggattcttt gtatcagtag aaaaaccatc
    11341 aatttctact gttatatctc ttggtagagg gcttgtaata gttgttttaa gtctaatttc
    11401 aatgatacta atatttggtg gacaaggaat atggatgact actattgttt ctgagtttat
    11461 atgtcttatt ttatcattag tttttctaaa aaagaatttt tctacattag actctaatct
    11521 aaataaggtt gcttagatga taagagtgac aatatatgaa aatatctaaa taaaaaatac
    11581 ctattataca atcttgcaaa tattaaacct ttgcaaaaat taggattata taataggtat
    11641 tttatttatg taattatttt atttctaaat atccatagcc atcttttatt aaagttcctt
    11701 ttacttcata ttctacaggt tttttaaata ttggaccatc tacgacaaat gtatgatact
    11761 ctccatgttc tccacatggg tctgcaccag cattttttat cttctccaca agttctctag
    11821 ttaatttttt tcctaaaaat tcctctccta agtgctttaa gtttactttt gttacaacac
    11881 tacaaaatcc actgtctata aattcatata ctaactcctc tctactctct tgccataatg
    11941 gtaaatctac tttcatacca actgcttcac atctatcagt atcccatttt ctatgacttt
    12001 ctatatctat atctccatat gcacatatag ttgctcccat gtttttagct tttattaaag
    12061 ccctctcaaa gctctcttca tatccttcta caccacactc agcaactaat aaaggtaatc
    12121 ctatattgct acttacttgc ttaagcatat tatattctaa attatgtgtc catgactttc
    12181 catgttcttc acttatagtt gtcaagagtg ccacaggctt atatcctttt ttcaacattc
    12241 gatttaatgc taatatacta tccttaccac cactaaatga cattacaaat ttttcatcag
    12301 ccaattttaa cacctctttc atctaacttt gttttattaa cataattata ccaaattttt
    12361 gagttgcata gcaaattata ttaaattgtt aattcactat aaagaatgtc cctaatatta
    12421 aaagtataac ccctatgtat ttgtataaat gcattgtttc ttgtcccaaa attacgctat
    12481 caataaaaaa tccaactaaa acttgggata caagagttaa tataagtgta tttgatactc
    12541 ctaaatttgg aattgccttt actgtaaaat atattattag acctccaaat actcctccta
    12601 ataacaactt ataattaaaa ccatttatag atactagaca ctttaagtca cctgtaacta
    12661 ttatacttgc caaaaaaaat attgctccta cagttaagct tataaaggtg gccactaatg
    12721 ctgttgtact ttttcctagc tctccattta taaaagcttc aagagctgta gaaccacctg
    12781 ctaataatgc aaatattatt gcccataatt ttgtcatgga caaacctcct tctatataat
    12841 tctattaata gaagtttatg atacaaccta ttaattaatt actaagtata gtttaatttt
    12901 tatacactag gctttatttg gatatgaatt tctgttataa ttgttctatc gattttggag
    12961 gtgattttat gtacacaaat tttaatatcg attttaataa ctttaataaa aaagaaaatg
    13021 ctattaaatt tatgttaatg ggagtattac tcattatatt aggattatta tgccttacat
    13081 ttaagacatt aggtataaaa ttaatttctt ggacttttgg tattgcactt ttattctttg
    13141 catatttaaa tttaaaaaat attaatgaat taaaaagata tgctactaaa gaagaaatta
    13201 aaccctctat taatatccaa tgggttctaa taattgcatg tatattactt tttgtatttc
    13261 ctcaaaaaat acaaagcata ttttcattat ttttaggatt ttatttaatc tttaatcaac
    13321 tagtagcact tgtaaatagt aagaataatc cttattctaa atttacaact tggaatatag
    13381 ttaagattct atttggtata tgccttatat tatccccact ttttttatct agatttatag
    13441 tatcgataat gtcttttttc ataatattat ttggactagt tctatttttc tctggaaata
    13501 cagcgagaaa atattaatta ttttctcgct gtatttttat attacttaaa atagaatttg
    13561 tttaagttat ctatttgtgg taatatgttt tttgtacaag ctcagcgtac aattttatta
    13621 gaaataggtg attttttgga taaatttaaa tatgcttttg ataataaaag atatcatact
    13681 tggaattact atcttagaaa tacttttgga gaaaaagttt ttaaggtatc tataaatgca
    13741 ggatttactt gcccaaacat tgatggaagt cttggttatg gcggatgtac ctattgtagc
    13801 aaagaaggct caggtgattt tgctggaaac cctaaagata atcttatcag tcaattttat
    13861 aatataaaag aaatgatgtt aaaaaaatgg cctcatgcaa agtatattgg ctactttcaa
    13921 gcctatacaa atacgtatgc tcctcttgaa gttttaaaag aaaaatatga gactatatta
    13981 gagcttgaag atgtcatagg tctttcaata tccacaagac ctgactgttt gccagatgat
    14041 gttgtagaat acttatctga actaaataaa agaaccaatt tatgggttga acttggactt
    14101 caaacaattc atgattctac atctaaaatt ataaatagag gtcatgatta taaaacattt
    14161 gttgaaggtg ttgaaaaact aaagtctaaa aatataaagg ttgtcgtaca cattataaat
    14221 ggtcttcctg gtgaagatta taatatgatg atggaaacag caaaggcagt tggtaaaatg
    14281 ggtgtagacg gtataaaaat ccatctattg catgttataa aagatactcc tatggaaaag
    14341 atgttacaaa atggtatgtt aactcttatg gaacaagatg aatatatcaa tcttgtctgt
    14401 gaccaattag aaatacttcc tgaaactatg ataatccata gactcactgg tgatggtaag
    14461 agggatgaac tagtaggtcc tatatggagc ctaaaaaaat gggaaatttt aaatcaaatt
    14521 gatgatactt taaaggctag aaattcttat cagggctgta agtttgttta atacaaaata
    14581 ataactatag aaatggttat ataaatatag tcctttctat agttatttag tatttacaaa
    14641 acaaaatatt aatttgtaca tttatacaat atataataaa aaatagatag tctaaactgt
    14701 atctacttat attttatttg tactgtccac tttattctat aaaatttata aatagttatt
    14761 ttttaatacc aaatataatt tggtataatt tttgttggac tctaaaatgt ataccaataa
    14821 atccttttta agtatataat tctaaatact ttcagttttt tcaatctgct ttaacttgtt
    14881 ggacttataa aatattctta tttcatcata agaaagatta agtgctacta ctgcagatat
    14941 taacattaac atcactccaa ataacttccc taaggaaaaa ctttctccta atatagtgca
    15001 accaattatt actgaaccaa ctaattctac tgatgccaca acacctgcaa ctgacaactc
    15061 tacaccttta gatatacctg ctgcataaaa aatatatgca agtgcagctg gaacaatgcc
    15121 taacattagc atacaagata aaacatctaa atccttagca taatttaaga tttcccaagg
    15181 tcttgaagaa ggaatcataa atatagctcc aaataagaaa ctgtatacta atattgttga
    15241 acttgaaaat tcctttaaag catttttact aatagttggc ataagtgcat atgctattgc
    15301 tgataatacc ccaagtaaaa gcccaaaagc gtttaaacct tgaaaatcca aacgtccacc
    15361 agtcactgcc ataattgcac caataaaaca aagaataagt gaaaataatt tgcttctagt
    15421 aatattttct ttataacata attttgaaaa tattgctaaa aacagtggtg atgtatatag
    15481 taaaactgct gcaattgata cacccgcaat gtcaattgct ttaaaataac ataaattaaa
    15541 cattgcctga catataattc ctattattac tgaatatata attccttttt tgtttatctt
    15601 taagatttgt ggtgtcctta tagatgaata tacgcctaaa actataaatc caaaaaacaa
    15661 tcttgtaaat gctacttgtt ctgatgtcag tccatttccc attaaaaact ttccaaataa
    15721 tccaagtgta gcccataata accctgctat tgctataaat acataccctt tacttttttc
    15781 tcccatttta aattcccttc tatttttatt tagtcaattt acactcttct ttttaagcaa
    15841 aaactatgcc atcttaaatc aatatatatc gactctaaaa ccctagtctt tccaataata
    15901 ctaataaatt ttcaattttt ttatatttat ttttcgctta ctttaagttg atttagactt
    15961 attttaattg taaaatgagt tatatataac ttatttaaag ttaaaataga ctgaaactta
    16021 tatataaata tcaaatttta agtatattaa tcaattaaac ctattttaat atatcattaa
    16081 aaatttagga ggaaaatata aaaatgaatt tagatttgga attttatcaa aaaatattag
    16141 aagcttccca tgatgaaata tgtgtttctg atgataaagg aataataata tattgtaata
    16201 aagcatttga agaaaattat ggtctaaaaa aagaagatat tttgggaaaa aatgtttctt
    16261 ttttagaaga ctctggatat tcaacaaaaa gccccatacc aattgtatta aaaacaaaga
    16321 ctaaattttc actggaacaa gatactcaaa cagggaaaaa gcttatcata actgctaccc
    16381 ctatatttga tgaaaatgga cacttagaat ttactgttga aaattgtaga gatataactg
    16441 aacttaataa tataaaaaat aaacttgaag acacaaaaaa gcaagtaaaa aaatataaat
    16501 ctgaagtaga aacactatac agaactgcac ttagaattga agatactgta attatggacg
    16561 gaatagttat gagaccaatc ataaacacag taaatcatgt ttctaaaacg gatgtaagtg
    16621 tacttttatt gggtgaatct ggaacaggaa aaagctcact tgctagatat atacaccaca
    16681 acagcaatag atctaatggc ccatttataa caataaattg tgcaactata tctccacaac
    16741 ttcttgaatc tgaacttttt ggatatactt caggtgcttt tacaggtgca agtactaaag
    16801 gtaaagttgg gctcgtagaa ttagctaatg gaggaactct ttttttagat gaaataggag
    16861 atataccaca aaatctacag gcaaaatttt tgcaattaat acaggataga acttttactc
    16921 cagttgggag cttaaaaaat aaaaaggtcg atataaggat tatatctgct acaaatgttg
    16981 atttagtttc aaaagtaaaa gaaaaaaagt ttagagaaga tttatactat agattaaatg
    17041 ttatagaaat aaaattgcct cctcttagag aaagaaggga taatctagtg gaaattataa
    17101 aatattattt taataggtac tcaagtgact tcaacctaaa taaaactatt tctaaggaag
    17161 ctatggatgc tattgcaaat tatagattcc caggcaatat aagagaatta caaaatataa
    17221 ttcaaaaaat cttgcttact tgtacagata atcatataac aatagatgac ttaccaaaca
    17281 ttcttacaaa aaatatacat attaccaata atggaaataa aacacatata tcccaaatta
    17341 ataaggttat tatatctgac tcaaaatcta ctaattataa aaataaaaat tttgacactt
    17401 taattaaaga gtatgaaaaa aatataattt tggatgctta tgaaaaattt ggtagttctt
    17461 ataaagtagc caaacacctt gaaatctcac agtctaaagc caataggtta attagaaagt
    17521 atactaatac ttaattttaa atttgataaa taaaaactta acactattta catattgtaa
    17581 atttggccat ttactgttat tatgaatatg gttgaaatta tttaaataaa tactgttgac
    17641 ttagtttcat atatttacca ttaaactttt atcataaata tcatatcata ataatatatt
    17701 taataagtct aataaactat acgaggtgta aatatgttaa tgaataccca ttttattatg
    17761 gcaaaatcaa tacttgataa tatagatgaa aataaaacat tctttataag cgaaaaaaat
    17821 tttatatatg gcaatataaa gcctgatgct ttttctaaat ataaattaaa aaaacattat
    17881 ttagatgagt catttaatat gattgtttct aaaataaact atctatgcag tcttaatata
    17941 gatagtcttt ctaaatactt ttcagtaagt agacttagtc aggaactagg agtcatatgt
    18001 cattttttat gtgatttttt ctgtgtagct cacagtgaac gttgggagtt taagcatagc
    18061 ttaaataaac atgttactta tgaaagagaa cttggagcat ttgcaaaaga tgttgattta
    18121 tctaaaatta aatgtggtac tataaatagt agttttgaga agttttttac taaactttat
    18181 agcgattaca aaaagaaaac tgattatatg aatgatttaa aattttcagc ttatacttgt
    18241 aatagtgtca taaattatat acttgactct attttatcta atacaataaa atcatatcat
    18301 atagcaaatt gcggttaact taagaatttt taaacttata taagcttata attgaatata
    18361 attaaaatga ctgctctata gaatataatt ttatacttct ctaggacagt cattttttat
    18421 actaactatt tatctccatt ataacatcta tggcactttt tacactatct actacataat
    18481 ttgcactttg ctttacatct tcccttgcct tagacattgc aaaactatat ttaaatcctt
    18541 ctaacatgca aatatcattt ggagaatccc caatagtagc aacttcatct ggacttacat
    18601 ttaacgtttt tattacatgc tctatacttc ctctttttga cacactttta ggaactatat
    18661 ttaaagtata tgttccagaa aaatatattt ctaagacttc actaaactca ctttttagat
    18721 aaagttctat tctggataac tcttccaaat tttcagaaca tacgcctata tttcctataa
    18781 gattatcaaa actacttctt ttttcaaaat ctgggtcaac tataaagtca ctagaataat
    18841 gtctaaaagc agtggtatca ctacccacaa ttacatcacc cttatattta aaataaagtt
    18901 gtgcatcact tgactcaaat ctatcaatga ctttttttac taaattatca tctatcgttc
    18961 ttttaaaaat tacattataa tctttatcat atataaatga accattttca catacatagt
    19021 atccattcat atctaaacta tctttgataa tattatgtgc ttgtttaaaa attctacctg
    19081 tagcaacatt aaactgtact cccttttttt ctatttcttc aattgctact atatcttctt
    19141 ttgttatggt tccattttca tatagagttc catctaaatc acaaaatata tgttttatca
    19201 taaattaaaa gcctccaaaa acaattttat attttactaa tactttaatc aaaataactt
    19261 aaagcttttc taattgtatt ctcaattcat taagcaaatc tctagtagct cttaatctta
    19321 tctttcttct atccccatta aatatatttt tctttactat tgtttttcca tttatatata
    19381 ttgcagtata aaccagtccc acaggcttct ctttggttcc tccaccaggt ccagctactc
    19441 cagttgtaga tatacctata ttagctttaa gtcctttagc aacgccctca gccatttcta
    19501 tagctgtttg ctcacttact gctccaaact cttccaaagt ttctcttttt actcctaatc
    19561 ttttcatttt agaatcatta gaatatgtta cacaaccttc aagaaataca gaggatatac
    19621 ctggatagtt tataagagat gaagaaacca aacctccagt acaagattca gccactgcta
    19681 ttgttagatt tttttctaca agtagcttag aaacagcatc ttctaaagca gtctcccctt
    19741 cagatataga aatatctcct tcagtatata catatttacc aactctactt tttatttttt
    19801 cttctactgg ttttattaat ttaaaagctt ctctttcatt ttcagccttt gcagttattc
    19861 ttattgtaac ttctaattct tttgcatata aagcaactgt tggattagtc tgctcattaa
    19921 ttatatcgag aatttctaat tctagatttg actcacctat tccatataat cttaaagtct
    19981 tagatactag catttcattt gtgaattgtt gtaagtaagg tttgacactc tcattaaaca
    20041 tagctttcat ttctcttgga ggtccaggca atactattat aaatttacca tcttttttta
    20101 aaattgcccc tggagctgta ccattattat tttttagtac tatagcatct tttggaaagt
    20161 acacttgttt catattattt tcggccattt ttttccctgt tttaacaaag aaagattcca
    20221 aaacctctag tgaaggttta tgtagttcta atttctgacc aaagtattct gcagcagttt
    20281 cttttgtcat atcatcacca gttggcccaa gaccacctgt agtaattaca aaatcacttc
    20341 tctttaagct ttcatcaaaa cattctaaaa gtctttgttt gttatctcca acagtactct
    20401 gatggtatac ttctattccc aatgatgcaa gttctttagc taaaaattga gaatttgtat
    20461 ttactatatc tcccaataat atttctgttc ctacacttat tatttcagct ttcaaaattt
    20521 atcactcctt gatttatagc cattaagact agtcttaagt tcataacaat aattttagca
    20581 aaaataataa cataaataaa gttaaaaaat catttaaaca tatctttaaa ctagattatt
    20641 attctaaaac cacacataat ataaacttcg tatatagtgg tactttcatc ctcaactgtt
    20701 aattcatata attaagtatg taaataaaaa gtttacttta aaataataaa aattaaaata
    20761 ggagtgtata atatgaaaat agcagttata atgggtggaa tatcatcaga gagagaagtt
    20821 tctttaaatt caggaaaaga gatatataat aaccttgata aaaataaata tgaagttgta
    20881 aaagtaataa tagatgataa aaaagatata tttacaaaga taccagaaga tatagatttt
    20941 gcaatacttg ctttacatgg aaaatttggt gaagatggat gtatacaatc aatacttgag
    21001 actatggata taccatactc tggatgtgga cctctttgca gtgggatgtg tatggataaa
    21061 aatataacta aaaaaatgct tagagattca aacctaccta ctgctccatg ggttttagta
    21121 aaatcagttg atgaaataga ctatgatgaa atagataata taggttatcc agtatttata
    21181 aaaccaaact caggaggttc aagtgtagcc acattcttta ttcattctaa ggatgaagtt
    21241 gaagaagcag ttagaaaagg tctggaagtt gatgaatttg taatgattga aaaatatata
    21301 ccaggtggag aatatacttc attcatatta aatggagaag tgttccctac aatatctata
    21361 aaatctgatt caggattctt tgattatgaa gctaaatact cagttgaaaa aggtgcaaag
    21421 gaagaagttg tttacttaga tgaagaactt caaaaaagag taaacgaaat ttctgagact
    21481 tgttggaaaa tttttaattg caaagcatat gtaagagttg atatgattat aagtgaaggt
    21541 attccatatg ttcttgaact aaatactctt cctggaatga ctcaaactag tttaattcct
    21601 agaagtgctg ctgctagagg tattaagtac agtgaactat tagataaact tatagaatac
    21661 tctttaaatt agatgaaata atttgaggtg gtaatttgat attttcaaat ctaaaattaa
    21721 atgataatga accaatttat atacaactta aaaattatat aagtgatatg atatcaaaag
    21781 gactaattcc agacaatagt aagctccctt ctacaaggga gcttagtcag cttttacaag
    21841 ttagccgaaa ttctgtagtt ttaacttatg aagaattaaa atcagaagga ttaatctact
    21901 ctatttcagg aaaaggtaca tttgttaaat caaagaataa gtcttcaaat actacatggt
    21961 cattaaactg ggattgttta gagaatacat actctaaaaa agccaatgaa ttggacatta
    22021 taaaaagtga aattccttgg agctctgacc tgatttcctt taaaagtatt tctccagatg
    22081 gagatttatt cgacatggaa gaattaaaaa aatccttttt aaatagaatt tcactagaag
    22141 gacataaatt actcaactat ggatatgcac aaggttataa gccacttatt gactatttac
    22201 tagaatatat gacaaacaaa ggtgctgata taagtaataa agatatacta ataacaaatg
    22261 gattcacaga aggctttgat attattatgt catcttttac ccaagaaaaa gactacataa
    22321 tatgtgaaaa tcctactcat aatactgcta taaaaattat gaaatctcat aacctcaata
    22381 tcttaggtgt agatataaat gaagatggtt tggacttcaa tatgctagaa gacaatttag
    22441 ttaagtataa aaataaaata aagtttgcat acattacacc ctcttatcac aatcctacag
    22501 gaattgtaat gactcctgaa aataggtaca aattctataa tcttatgaaa aaatacaata
    22561 tagcaattat agaagatgga tttaatgaag aattactcta caatagttct catatatttc
    22621 ctatctgttc cctagataat atgaataatg gggtcgtata tattggtagt ttttcaaaaa
    22681 ttttatttcc tggaatgaga attggatgga tatttgcaga taaaaaagta atcaataaac
    22741 tagaaagtgt aaaaaggtgc agaaacatac atgtatcctt tttagaccaa ggaattttat
    22801 ttgattattt aagtaatgga ggttttgaaa aatacattaa aaaaatacgt aaattctatg
    22861 gagataaatt taactttgca tataagtgta taaaaaaata tataaaaaca gaatatatct
    22921 tgggtgatgg tggtttgcat atatttataa aactaaaaaa tatagatact agagttttat
    22981 tagaaaaatg ttatgaaaaa aatgttatat ttatgcctgg agatttattt tttacagata
    23041 actctggttt tgatacttta agactcgggt tttctaggtt gtcttttgaa aacattgaaa
    23101 ttggaataaa aataattgga gaaactataa atgaaatgtt ctaggttaac taaatattgt
    23161 tagcctagtt tatttttatg aggtataata tatatagttt atatgaatct aatactgggg
    23221 gataatatga gtaaaaagtc aaaacgaaga aaaattaata aattaaaatt aacgattgta
    23281 ataactgtat tatttcttgc tttattatct atatatgaga tactgttctc taatcccaac
    23341 aaaaaaggta atataaagag tcaagaaact atgcaaaata aaaataatac aacagatgat
    23401 tctaaaaata atcaaagctc taccaaaaag caggaagata ataatatcaa acctactttt
    23461 tcatattctt caataccaga taatataaaa aataaaatga tcggtaaatc tatgcctact
    23521 gatgaaccta taagctttga tagtctatct tatttaaaac ttacatatta tggatttgat
    23581 gaaaaaactc atcaaggaga aatgatagta aacagtgaac tagctccaga agtagtggat
    23641 atttttaagg aattatacga aaaaaaatat ccaattgaaa aaattaagtt aatagatgac
    23701 tatgatgctg tagatgaaaa atctatgtct gataataata cctcatcatt ttgttataga
    23761 actatagctg gtacaaatgt agtttcaaat catggtaaag gacgtgctat agatataaac
    23821 ccattacaga atcctcaagt ttctggaaat gatgttacac ctaaagtaag tacagtttat
    23881 gctgataggt ctagcacaaa atttggaatg ataaaaaaag gtgatgattg ttataatgct
    23941 tttgtaagca gaggttggag ttggggtggc tattggaaaa acccagatta tcaacatttt
    24001 gaaaaataat agattagaaa taaaggtgaa ttatatgaat ttaatgacat tggaaaatat
    24061 aagtaaaagc tattctgaaa aaaaattact agaaaatata tctcttggaa taaatgaagg
    24121 ggaaaaaata ggacttattg gtgtaaatgg tactggtaaa tctaccttac tcaaaattat
    24181 tgcaggagtt gaagaaagtg agactggtaa tataacaaaa actaatggta ttaggataga
    24241 atatctacct caaaatccaa cttacaatga aaattcaact gtacttgaac aagtatttaa
    24301 tggaacttct gaagaattaa agctacttgg tgaatatcaa gaaatcctag aaaaacttaa
    24361 ttcaaacttt acagaggaat taaataaaaa attattatca gtacacgaaa aaatagatgc
    24421 cttaaatctt tgggatttag aaagtgaagc taagtcagta cttacaaagc ttggtataaa
    24481 tgactttaat caaaaaatag cagaactttc tggtgggcaa agaaagagag tctctctggc
    24541 atcagccctt attacacctt gtgagttttt gatactagat gagcctacaa accatctaga
    24601 caatgatact atagattggc ttgaggaata tcttaattcc agaaaaggtt cattgcttat
    24661 gataactcat gatagatact ttttagaccg tgttacaaat agaattattg aactggacaa
    24721 aggtagatta ttcagttatg atgggaatta ttcaatattt ttggaaaaga aaatggaaag
    24781 actttcgcta gaagcaagta ttgaagataa aagacaaaat ttaataagaa cagagcttgc
    24841 gtgggtaaga cgaggagctc aggctcgtag cactaaacaa aaagctcgtt tacaaagatt
    24901 tgatgaactt ataaatagag attcttttaa acctgatgaa aatcttgata tatctgttgc
    24961 atcaagtaga cttggaaata aaataataga aatacacaat atatctaaat catttgaaga
    25021 aaatactgtt atagataatt tagaatacac tttaactcgt acagatagaa ttggtataat
    25081 aggcaaaaat ggtatgggta aatctaccct tataaatata cttaatggag aaatagagcc
    25141 tgatagtgga tatatttcaa ttggagaaac ggttaaaata ggttgttttt ctcaagacga
    25201 ctctcatatg aatattgata tgagggctat agactatgta aaagaagcta gtgactatat
    25261 agaaacttca gatggtacta ggattacagc ttctcaaatg tgtgaaagat tcctttttaa
    25321 tggtactatg caatatactt tgataggtaa attatctggt ggtgaaagaa gaagactaca
    25381 tcttcttaaa atccttatga cagctcctaa tgtgcttctt ttagatgaac ctacaaatga
    25441 tttagatatt gaaacgctta aaatattaga agaataccta gacgaattta aaggtgtagt
    25501 agttacagta tcacatgata gatatttctt agatagaatt tgtaataaaa tatttgcata
    25561 tgaaggtaat ggaaaaattc atatctatac aggtaattac agtgattatc ttatttatag
    25621 agagattcaa ggaattgaat ttgaagaatc taaaagggaa tcagttaaaa aagatgactc
    25681 tactacccca aaaaaagaaa aacctaaaaa tgataaaaag cttaagttct catataatga
    25741 acaaagggag tttgaaaata ttgactctga tatagaaaaa ctcgaatcta aaattgcaac
    25801 acttgatgaa agtactgcaa aattttcaac tgattttact aaacttcaag aaattttaga
    25861 tgagaaatct aaactagaaa aagaacttga atacaaatat gaaagatggg aatatttaaa
    25921 taatctagct gatgaaatag ctaataataa gtgatattaa aataatctta agtttaataa
    25981 gttttgcttt aaatctgtaa tttataaata ttttaaagga agtgtctcaa aatgaacttt
    26041 ttagttttat gagacactct tttttatgag aaatcaaata tgttttcatc atttcaacaa
    26101 tacaaaagag gcttatctct attttgagac agcctctttc ataattacct tctaatttat
    26161 atgctctaat atatctataa taattcttat tatatctata tatccagtct ttcaatatag
    26221 tgacaattaa cttcaatatg atttaaaaat actaacaacc tttcataaag tggatgagat
    26281 tcttctccat atttagcttc taggttcttg cctatttctc taacagtcct ttgaccatca
    26341 atttgtaaaa aaacaaaact ggaatattca tctagttcta tttttttgta tttaggtatt
    26401 ctagctttta actttctaaa aaacttttga attttatggt cctgtttttc aagtatagta
    26461 acaacactat tttcagctac ttcatattca agtccatcag taattttaaa tacaatatct
    26521 aaaacatcat tactcttgct cattattttt tactttagat aaaacaatag gtaatgctgt
    26581 aagcacaact aaaactacta ataaagcaat tgccattgaa tttgttgcag caaatccact
    26641 tggtaccttt ggagttacaa ctccagttac ttgtaatatt atacctatta aaccaatgat
    26701 agaaccacca gcaacaagac cagaagataa acttatacca ttagaaactt taacttcttt
    26761 ttctttttca gttttagata ctaattcaac aaataaacga attaatgctc caactaatat
    26821 tatagaagtt gttgcaattg gtaaatagaa tcctatagct atagtcatta ttggtaaatt
    26881 taatgcatat agaacgattg ccataaatac tccaacaata atcataaccc aaggtaaact
    26941 acctgacata ataccagaag ttaatgttga cattaagttt gcttgtggta atgcaaattg
    27001 tacattatca ccagttgctc taagttggtc agaaagtaat aaaattactc ctacaacaac
    27061 tataacacca actatacttg caattgtaaa gtaacgttgc atttcgtttt tgctaccacc
    27121 aataatataa gttacttttt gagattgagt ataacctcca gctatagcaa tagcaacaac
    27181 tataaatgaa ccaaataaaa gtaatgattt attagcttct aaatcagtcc atcccattat
    27241 aacaaacact aatgttacaa taactagaga agctatagtc ataccagaaa ctggaagatt
    27301 tgatgttccg attgttcctg ttaaacgacc agctactatg acaaataata aagataataa
    27361 aagagatatg atagctccaa taattgccat aacaatgtta ccagaaatta agaatgctgc
    27421 taaaaatcca ataactactc cacctaataa aagtatcatt tgtatagatg aaccttcttc
    27481 tccctctcca gcacttgatt tagctttaag tgtttctttt atagaagcga ttatagttgg
    27541 tataagtttg attgcaccaa taatacctcc acaaagcatc ataccagcac ctatatattt
    27601 tacataacta ctagatattg ctccaacatc catttggtta agaggcattg caggattatt
    27661 ccataccata gctccatctt tagccatatc tgtaaagtat cctattaaag gtgctatacc
    27721 aaagtttgat aaaatacttc ctgcaaacat tgttaaagaa acttcaagcc ctactataaa
    27781 tccaattcct aaaagtagag gatttacttc aatatcaaat ttccatttgt agaatttgct
    27841 tcctacaaga ctcattacat tgtttgctac atttaagaat gaaccagtta atacagtaat
    27901 aaatccactt attacaaatc caattcccat gtacttaatt gaatctccac cagcctctga
    27961 agcaacaagt gtttcagata tagccattga ttctgggtac ataagtttac catgttcttc
    28021 aactattaga tagttgtgaa ctatagcagc aattcctata ccaaataaaa ctccaccaac
    28081 tccaacagct aagccttcaa agaatgtaat ttggcttcca attaatataa ctgctggtaa
    28141 tacgaaaata aatccacttg caacagattc tccaccactt gacatacctt ggattaagtt
    28201 tttaccaaga ataccctttg aacgagcaaa tgctccaaca aaagcagaac ctattatagc
    28261 tcctggaata cctgcggcaa ctgtaagacc ggctttcatt ccagagtaag ttgtagatgc
    28321 ggcaaaaatg gcagctaaaa taataccgat aatcagtaca gctacatttc caccggttct
    28381 ggacttatct gtgatatatg gaacgtaatc ttttccacta acctcaccat aagcaccctt
    28441 aggtaatttt ttgttcataa aattttcacc ccttttcaat ttgtatatat tataacatat
    28501 atacatataa aacttaactt tttattattt tacaaatagc gagtcaaaac tactaaaatt
    28561 taaccctata ttattaattt ctacttttag atatttttat gctaattttc tttttatttt
    28621 tcaattctac taaaaactat taagatataa aataaaaaaa ttttttaatg taaaattaat
    28681 tttgtaaaaa aaatgcttta aaacacggaa aagtataaaa aatacaataa tcattcttat
    28741 aaataaattt tcaccatagt aaatatatac agaaaattct tgtttttatg caaattgatt
    28801 cttttataaa aataagtgtc ataaagaaat gtctgaaatc actttatgac acctatcata
    28861 ataaaaaatt attctggtaa tgctctttta tttacttttc cgattggtgt aactggtatc
    28921 ttatctatcc tcattattat tgttggaatc atatatggag gtagatgctc atttaaatat
    28981 tctctaatag ttctttcatt tatcttacca ctatcttcct catcaattac ataatatgca
    29041 catatataca tatctccatc atcatttgtt ctcgatatac aaacaacact tttaatttct
    29101 gtaatattat ttattatatt ttcaatctca tatagctcta tcctaaactc atcaattttt
    29161 acctgattgt ccatccttcc aatataatct aaatttccat catctaacca tcttactaaa
    29221 tcaccagttc tatacattaa cttattatgt tcacaagttt tgtaaggatt ctctacaaat
    29281 acttgctctg ttagcccttt tttatttaaa tatcctcttg atatttgaat gcctgataga
    29341 catagctctc ctggtgctcc aattggacat agtttgttct ttttatctaa tacatatgca
    29401 taagtattaa atataggttt tcctattggt atttttccat attctctgtc cacatgaaaa
    29461 gaagtcgata caacagtaaa ttcggttggt ccatactcat tatatagttc ataattacgc
    29521 tttctatatc cttttaatct ttctcctccg gtctgtacaa ctctaagtga attattattg
    29581 caattttgta taaataacct tgcaaatgct gttggcaatg ctagtatagt tatgtcattt
    29641 tcctcacagt attcatttac tgtatattca tcaaatttag cttcttcagg cataatatct
    29701 attgatgcac ctacaagcaa ataagggaat agttgtttca ttacagcatc aaaactgaaa
    29761 cttaagtata taccacatat atcattttct gtagcgctta tagattttac gctataataa
    29821 cacatattta ctaaactctt atgttctata gctatggtct ttggcctacc agttgaccct
    29881 gaagtagata tcgtatatgc acaatttgat gatgttattt tttcagttaa ttcatatcca
    29941 agcttaaaca tttcttcatc atttatatcg agtactatgg tattctcatt tacaacctta
    30001 cttttgagtt catctgtagt tatcactact tttgcattac tatcttcaag aaggtaattc
    30061 aatctttctt ctggattact tgtgtctatt ggaaaaaatg ctccccctga tttcataatc
    30121 cctattgctg taataattat gttaatatct cttggtaaca ttacagctac tatgtcttca
    30181 ctttccactc ctatatgatt taaataacct gcaagtttat cagttacttc atccaattct
    30241 ttatatgtta actttctatt ttcatcccta gcagctatat tactaggtgt taccttaact
    30301 tgttccctaa ataaatcaac ataactttta tcatagggta tttcatattg attattatta
    30361 aagtcttcca ataatacttt ttcttcttcc ttacatacaa attctaaatc ttctattaaa
    30421 atatcattat cttctattat ttgctctatt atataatcaa attgatttaa aattcttcta
    30481 atagtttctc ttttatatat agatggttta tactttattt ttattttaag tgccctctta
    30541 gtatatacta ttacagataa atcatatcct tttttttcta tgtcataatc atatgataaa
    30601 tcaaaacttt tagctataaa tattgtgttt ataagcttag tatttagatg atttttattc
    30661 tctatatctg ataacaaata gtatccatac tctaaagacc tgctccactg cctttttagc
    30721 ttccttacaa catctataaa tttttcactt tgtctaactc ttactcttat tggaattata
    30781 ttcattgttt taccaaaaac tacatcatct tcatatatat acttttgaag tataaggcca
    30841 tatatagttt ctatgataga gtctatgcta atattgttca ctttagaata ttgaattaac
    30901 ctttcatgtt tctcaatatt catcttaaaa acctcatcta ctacttcatc agaacaatct
    30961 ttataaaaaa aatcatttgg aatttttgct atattcgtat aatcatctaa caaatccatc
    31021 caataattca tagctcgttc taaattaact tcatacatat caaaattccc ccttactact
    31081 aagtctatag aaaaaattct tttggaattt tattttcaca atatataaat atattaataa
    31141 tacatatgca agctctaaaa acatgagctt gcataaaatt acacttatta tgactactaa
    31201 attcgtaata tttacaatgt ttaaaatata ttataacaca tatatgattt tatttttcta
    31261 catttatata ata
//
LOCUS       DAEPXW010000043        30760 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.044, whole genome shotgun sequence.
ACCESSION   DAEPXW010000043 DAEPXW010000000
VERSION     DAEPXW010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30760
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.044"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(226..795)
                     /gene="yfcE"
                     /locus_tag="KRM55_001950"
     CDS             complement(226..795)
                     /gene="yfcE"
                     /locus_tag="KRM55_001950"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBH1594195.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGGILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(820..1620)
                     /locus_tag="KRM55_001951"
     CDS             complement(820..1620)
                     /locus_tag="KRM55_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBH1594196.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            1755..2615
                     /locus_tag="KRM55_001952"
     CDS             1755..2615
                     /locus_tag="KRM55_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594197.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            2615..3301
                     /locus_tag="KRM55_001953"
     CDS             2615..3301
                     /locus_tag="KRM55_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH1594198.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            3353..3895
                     /locus_tag="KRM55_001954"
     CDS             3353..3895
                     /locus_tag="KRM55_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594199.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            3974..4441
                     /locus_tag="KRM55_001955"
     CDS             3974..4441
                     /locus_tag="KRM55_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBH1594200.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            5150..6286
                     /locus_tag="KRM55_001956"
     CDS             5150..6286
                     /locus_tag="KRM55_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBH1594201.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            6345..7127
                     /locus_tag="KRM55_001957"
     CDS             6345..7127
                     /locus_tag="KRM55_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1594202.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            7146..8156
                     /locus_tag="KRM55_001958"
     CDS             7146..8156
                     /locus_tag="KRM55_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH1594203.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            8175..8972
                     /locus_tag="KRM55_001959"
     CDS             8175..8972
                     /locus_tag="KRM55_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH1594204.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASSKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            9070..9915
                     /locus_tag="KRM55_001960"
     CDS             9070..9915
                     /locus_tag="KRM55_001960"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBH1594205.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            10002..11177
                     /locus_tag="KRM55_001961"
     CDS             10002..11177
                     /locus_tag="KRM55_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH1594206.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            11373..12275
                     /locus_tag="KRM55_001962"
     CDS             11373..12275
                     /locus_tag="KRM55_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH1594207.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIYEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            12289..13293
                     /locus_tag="KRM55_001963"
     CDS             12289..13293
                     /locus_tag="KRM55_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBH1594208.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(13437..13664)
                     /gene="acpP"
                     /locus_tag="KRM55_001964"
     CDS             complement(13437..13664)
                     /gene="acpP"
                     /locus_tag="KRM55_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH1594209.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            13836..14261
                     /locus_tag="KRM55_001965"
     CDS             13836..14261
                     /locus_tag="KRM55_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594210.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            14309..14515
                     /locus_tag="KRM55_001966"
     CDS             14309..14515
                     /locus_tag="KRM55_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594211.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            14697..14876
                     /locus_tag="KRM55_001967"
     CDS             14697..14876
                     /locus_tag="KRM55_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594212.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            14910..15110
                     /locus_tag="KRM55_001968"
     CDS             14910..15110
                     /locus_tag="KRM55_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594213.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            15363..16379
                     /gene="ccpA"
                     /locus_tag="KRM55_001969"
     CDS             15363..16379
                     /gene="ccpA"
                     /locus_tag="KRM55_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBH1594214.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(16502..16900)
                     /locus_tag="KRM55_001970"
     CDS             complement(16502..16900)
                     /locus_tag="KRM55_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594215.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            17112..18020
                     /locus_tag="KRM55_001971"
     CDS             17112..18020
                     /locus_tag="KRM55_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594216.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDYDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEE
                     LYNINEQESEYNYNEKNTKTRAKKKR"
     gene            18135..18315
                     /gene="ssrS"
                     /locus_tag="KRM55_001972"
     ncRNA           18135..18315
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KRM55_001972"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            18498..19715
                     /gene="cdeC"
                     /locus_tag="KRM55_001973"
     CDS             18498..19715
                     /gene="cdeC"
                     /locus_tag="KRM55_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBH1594217.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(19815..21137)
                     /locus_tag="KRM55_001974"
     CDS             complement(19815..21137)
                     /locus_tag="KRM55_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH1594218.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(21188..21982)
                     /locus_tag="KRM55_001975"
     CDS             complement(21188..21982)
                     /locus_tag="KRM55_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH1594219.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            22092..23537
                     /locus_tag="KRM55_001976"
     CDS             22092..23537
                     /locus_tag="KRM55_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1594220.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            23566..23775
                     /locus_tag="KRM55_001977"
     CDS             23566..23775
                     /locus_tag="KRM55_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBH1594221.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            23795..25189
                     /locus_tag="KRM55_001978"
     CDS             23795..25189
                     /locus_tag="KRM55_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1594222.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            25429..26181
                     /locus_tag="KRM55_001979"
     CDS             25429..26181
                     /locus_tag="KRM55_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1594223.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            26207..26620
                     /locus_tag="KRM55_001980"
     CDS             26207..26620
                     /locus_tag="KRM55_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1594224.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            26624..27367
                     /locus_tag="KRM55_001981"
     CDS             26624..27367
                     /locus_tag="KRM55_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBH1594225.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            27367..27837
                     /locus_tag="KRM55_001982"
     CDS             27367..27837
                     /locus_tag="KRM55_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1594226.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            27854..28612
                     /locus_tag="KRM55_001983"
     CDS             27854..28612
                     /locus_tag="KRM55_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1594227.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            28596..29438
                     /locus_tag="KRM55_001984"
     CDS             28596..29438
                     /locus_tag="KRM55_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1594228.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(29598..30503)
                     /locus_tag="KRM55_001985"
     CDS             complement(29598..30503)
                     /locus_tag="KRM55_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1594229.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
BASE COUNT        11992 a         3419 c         5445 g         9904 t
ORIGIN      
        1 aaataagtaa actaagttat actccaatat aatatataat agaaacaagt aaactaagtt
       61 atatttcaat atagcatata ataaaacaag taaaccagat tctatttaat tagaagttta
      121 aggtattgta cttaaacttc taattgagat agaaataaaa tggtttactt gtttttatta
      181 tgagtttaat aaattaaagc ttattttatt tttattaaaa atttactaat cattgatatt
      241 tattatattt ccagtattga tgtcaattaa gtttatatca agttcaagct catcctcatc
      301 atcagttttt atgatatcta taattgcgac agaatggctt ccatcttttg ggatagaagt
      361 acttcctgga tttattacta ttaaattatc atccatgtat agttttttta catgagtatg
      421 tcctaaaact aatatgccac cacccatttt ctttgctttg tcaataattt cttcttctga
      481 ttctatataa ccatgattca atataattct aatttcacca aattggctca tgacataagg
      541 actctgaata ggatgttcta taaccatctg gtcaacatca gcatcacagt tcccttttac
      601 aatcacaatg ttttctaatt tatttaatgt ctcaataaat tttttaggat tatatccttc
      661 tggaatatca tttctaggtc catgatataa gacatctcca ccatgtaata aaacatcaca
      721 atcagataat acatttaacg ctttttcaaa gtaaagtaag ctaccatgag tatcactcat
      781 tattcctatt ttcatattaa aaatcctcct aagtacagtc tataaaaatt tttcagatac
      841 tctatgccaa aactcatagt ttgacattct aagtaatttt atttttgcat cagatatact
      901 aacttttata ttttcaattt gtctaaatct gtgctcaact ccatcaacga caatcaatac
      961 agaatcttca aatctatatt ctggtgcaat ctttataaca gattcatttg aacatattat
     1021 acttgatgta aagcacctat atgcattggt atttatcgga tgtaaaggtg taatctgcat
     1081 aagttcaaga tttatatcaa caatactacc tccagcagaa tagttatagg ctgttgaacc
     1141 tgtggaagta gaaataatca taccatctcc actaaaattt tgtatatgtt tattatcaag
     1201 gcttaaattt aggtgtatag tcctagactt gtctcctctt ataacaacct catttacagc
     1261 aagcatatta gaaccactag tagtagtata tacttccgca ttaagaagtg acatttcttg
     1321 aataatataa tctttttttg tataagcttc aataaagcta tcaatcttat ctggtaaaat
     1381 atcaggaaaa aaccccagat gacctgtatt tattcccatt atgggaatct caggaaaatc
     1441 gaaatctcta actgttctta aaaaagagcc atcaccacca attgatataa taagctctgt
     1501 gtctggataa atatctgaat acacttcaaa gccagcattg ataagttttc tagttaagag
     1561 ttctttagtc tcaagggact tatttaattg gtttgtattt atagttataa ttcttttcat
     1621 atattcacct cttcatactt tgtattataa catagtttta taattcttaa tttataaatt
     1681 tataaatgac ctttgtaatg aatgtgttaa aatatgtata ggtgggtata aaaaaatgca
     1741 taagaggtga agatgtgttt agcataagga atatcacaaa aaaattagga aaattcaagt
     1801 taaataatat aaacttagag ttaaaggaag gggatattgt tgggattata ggaccaaatg
     1861 gttcgggaaa aacgacttta ataaaaatta taatggggat tattgatgca gatgaaggtg
     1921 aaattgaact ttgtaatgaa actattgaaa attctccaat aagctttaaa aacaatattg
     1981 gttttgtata tgattcttta caattttatc cgcatttaaa ggttaaggaa tttagaaaaa
     2041 tagtttcttt attttataag aattttgata gagaaaggtt tgatgaatac cttaataagt
     2101 ttgatataga agaaaatatg catattgaaa atttatctaa aggtcaatct gaaaagctta
     2161 tgttatcaag cgcacttagt cataatgcta agttattgat tttggatgaa ccaactgctg
     2221 gtatagaccc aattgtaaga actgaaataa tgcagtactt acaagatttt gtgaaaaatg
     2281 gaagtagtag tgtaataatt tctactcata atactgataa tttaattaaa attgctgatt
     2341 atcttgtttt tataaataga ggaaatcaga tttttactgt taagaaagaa ttaatagaac
     2401 aagaatataa gataattagg gcaaataaag cagagttaga agcaattaaa gaaagcatag
     2461 ttggtgtgaa agagtataaa tattataatg aggcacttgt taaagttgga gatagcttga
     2521 aagtaaaaag cctattgata gaaattgata agcataaggt caaaaatcct actatagaag
     2581 aactaatgta ttattatgta aatgaggtga gatgatgttc aatttaataa gaaaagattt
     2641 aataataggg attagttcag atggtatccg taatttaaag tacatattgc tattttttgt
     2701 gttttatttt ttccttaatt caatttcata ttatacagta agtattgttg ttagttattt
     2761 gatatttata aatacatttg agtgtgatta tgaaaatgat tcaaggattt ttataaggag
     2821 tatgccagtt agtatagaag atatagttta ctcaaaatat ttattaggtg taggattaat
     2881 aatttctgta acaataattg tgtccttact aagtaaattg acatcactag tgttctttag
     2941 aaatatggtt ttaaatgatg tatttttttc tgtaaatata tttttagcaa ttttgacgat
     3001 tttactgcct ttaattttta agtttggata tggaaaaatg aaagtttgtg gttttatagt
     3061 aagtatttta atttactttg tatatggaag tcttttgaag atgattagta tgattgtata
     3121 tcaagtaaag cattttaatt atagtaaagt tggaggagta tatctttcaa attatgtaac
     3181 tgatatagct aatactaagt atataaattt atatagtatg acatttttaa caataataat
     3241 ttttataata tcaatgtatt tttctattaa gatttcaaaa aagaataagt ttaattatta
     3301 aaattttaat taatattata gcacaatagc acaaaatata aggagactaa aaatgaagaa
     3361 gtttataaaa gtttcatttt ttattttggg gatttttaca ctattcatag ctataaataa
     3421 attagtatat agagatatgg taagtgtcaa agattatgaa ataaatcatt tagaggaaat
     3481 tgtttttgat tttgatagca ggagaagtag agatgttggt actattgtaa gatttaaaat
     3541 aagcaataat agtaaatata gttataaatt aaacagtgct aaaatgaagt ttgaaaattg
     3601 tgtggaaaat aaaaagggaa tgaataagtg ttctgcatat gtaaatgtag atttatttaa
     3661 tgaaaaaaat tctataactg aaaggactct gaaatatgga ataaaaccaa ataatcaagg
     3721 ttatgttgat tttgtaattc caaaaggact aaattttgat tataggtact ttaatgaatc
     3781 tggtatgagt gtagaatata aaggagaata tattgtcaat attccaatgg caaaaggact
     3841 ttatctagta gttggaaaaa ataatgatac atggaatgct aatattatgg aataatttga
     3901 aaaataaatc aattatagat ataattaaga ataatatgaa atttataaaa gttcagacta
     3961 ggaggggtat ttaatgtcaa taagtaacgt aagagagtat tttaaacaat ttggcaagga
     4021 agacagtata ttagaatttg aacaatctag tgctactgtg gaacttgcag ctgaagcagc
     4081 tggggttatt ccagcaagaa tagctaagac actctcattt aaaataggag atgatgcaat
     4141 tttaattgtg acagctggtg atgctaagat tgataataag aagtataagg ctgaatttaa
     4201 ttgtaaggct aaaatgttga caccagaaga agtcttggag tttactggac atgctattgg
     4261 tggagtctgt ccatttggtt taaaaaattc tataaaagtc tatttagatg attcaatgaa
     4321 aagatttgat acagtatttc ctgcatgtgg cagtagtaac tctgcaatag aacttacatg
     4381 tgaagaaatg gagaagtttt ctaagtgtga aaaatgggta gatgtttgta agaattggta
     4441 aaaaaatata gtaaactata gtaggaatta gtaaaaaact acctctgtat acaatctata
     4501 cagagatagt ttttttgtgt aaatatttat aaatctaaga ggaaaatcta atttaaacta
     4561 ataatccaaa ataaagttaa aaaattctga ttttttttcg aaacaataaa aaaatgacaa
     4621 aaaagtggaa aaaatgtaat aaatattgtt aaaaaaataa ttagaaatta ttgaaaaatt
     4681 atcctttgag tgatactatt atagatgtaa gatatttaaa aataaaaaat agtcagataa
     4741 aaatacgatt atttagctct attaaaataa tttttatacg ataaaaatct tctgtacatg
     4801 gctaaaagac agatatacag acaatattta atgtttaata taccctaata taaatatcgt
     4861 aaacaaatta ttttatctgt aaccagtgtg aaagaaatct tattctaact tgaaatttca
     4921 caaaattcca aaaagcgaga ttttttttaa gtatagttga ttttaaatta acaatttatg
     4981 attaaattaa tgtcataatt ggttagtata atcacatata aatatagagc gtagtttgat
     5041 taaggttata aatttctcga cgtatattca aataccttat tatagatgtt gccgagattt
     5101 taattaataa atgaaaataa aatatttata aaatactgag gaggctatta tggatttaaa
     5161 ttctaaaaaa tatcagatgc ttaaagagct atatgtaagc ttcgctgaaa atgaagttaa
     5221 acctttagca acagaacttg atgaagaaga aagatttcct tatgaaacag tggaaaaaat
     5281 ggcaaaagca ggaatgatgg gtataccgta tccaaaagaa tatggtggag aaggtggaga
     5341 cactgtagga tatataatgg cagttgaaga attgtctaga gtttgtggta ctacaggagt
     5401 tatattatca gctcatacat ctcttggctc atggcctata tatcaatatg gtaatgaaga
     5461 acaaaaacaa aaattcttaa gaccactagc aagtggagaa aaattaggag catttggtct
     5521 tactgagcct aatgctggta cagatgcgtc tggccaacaa acaactgctg ttttagacgg
     5581 ggatgaatac atacttaatg gctcaaaaat atttataaca aacgcaatag ctggtgacat
     5641 atatgtagta atggcaatga ctgataaatc taaggggaac aaaggaatat cagcatttat
     5701 agttgaaaaa ggaactcctg ggtttagctt tggagttaaa gaaaagaaaa tgggtataag
     5761 aggttcagct acgagtgaat taatatttga ggattgcaga atacctaaag aaaatttact
     5821 tggaaaagaa ggtcaaggat ttaagatagc aatgtctact cttgatggtg gtagaattgg
     5881 tatagctgca caagctttag gtttagcaca aggtgctctt gatgaaactg ttaaatatgt
     5941 aaaagaaaga gtacaatttg gtagaccatt atcaaaattc caaaatacac aattccaatt
     6001 agctgatatg gaagttaagg tacaagcggc tagacacctt gtatatcaag cagctataaa
     6061 taaagactta ggaaaacctt atggagtaga agcagcaatg gcaaaattat ttgcagctga
     6121 aacagctatg gaagttacta caaaagctgt acaacttcat ggaggatatg gatacactcg
     6181 tgactatcca gtagaaagaa tgatgagaga tgctaagata actgaaatat atgaaggaac
     6241 tagtgaagtt caaagaatgg ttatttcagg aaaattatta aaatagataa atattaaaat
     6301 atacacaata ggtcgatatt aaaatagata tggaggaagg atttatgaat atagtcgttt
     6361 gtataaaaca agttccagat acaacagaag ttaaactaga tcctaataca ggtactttaa
     6421 ttagagatgg agtaccaagt ataataaacc ctgatgataa agcaggttta gaagaagcta
     6481 taaaattaaa agaagaaatg ggtgctcatg taactgttat aacaatggga cctcctcaag
     6541 cagatatggc tttaaaagaa gctttagcaa tgggtgcaga tagaggtata ctattaacag
     6601 atagagcatt tgcaggtgct gatacttggg caacttcatc agcattagca ggagcattaa
     6661 aaaatataga ttttgatatt ataatagctg gaagacaggc gatagatgga gatactgcac
     6721 aagttggacc tcaaatagct gaacatttaa atcttccatc aataacatat gctgaagaaa
     6781 taaaaactga aggtgaatat gtattagtaa aaagacaatt tgaagattgt tgccatgact
     6841 taaaagttaa aatgccatgc cttataacaa ctcttaaaga tatgaacaca ccaagataca
     6901 tgaaagttgg aagaatatat gatgctttcg aaaatgatgt agtagaaaca tggactgtaa
     6961 aagatataga agttgaccct tctaatttag gtcttaaagg ttctccaact agtgtattta
     7021 aatcatttac aaaatcagtt aaaccagctg gtacaatata caatgaagat gcgaaaacat
     7081 cagctggaat tatcatagat aaattaaaag agaagtatat catataattt aaggggggat
     7141 aaagaatggg taacgtttta gtagtaatag aacaaagaga aaatgtaatt caaactgttt
     7201 ctttagaatt actaggaaag gctacagaaa tagcaaaaga ttatgataca aaagtttctg
     7261 cattactttt aggtagtaag gtagaaggtt taatagatac attagcacac tatggtgcag
     7321 atgaggtaat agtagtagat gatgaagctt tagcagtgta tacaactgaa ccatatacaa
     7381 aagcagctta tgaagcaata aaagcagctg accctatagt tgtattattt ggtgcaactt
     7441 caataggtag agatttagct cctagagttt ctgctagaat acatacaggt cttactgctg
     7501 actgtacagg tcttgcagta gctgaagata caaaattatt attaatgaca agacctgcat
     7561 ttggtggaaa tataatggca acaatagttt gtaaagattt cagacctcaa atgtctacag
     7621 ttagaccagg ggttatgaag aaaaatgaac ctgatgaaac taaagaagct gtaattaacc
     7681 gtttcaaggt agaatttaat gatgctgata aattagttca agttgtacaa gtaataaaag
     7741 aagctaaaaa acaagttaaa atagaagatg ctaagatatt agtttctgct ggacgtggaa
     7801 tgggtggaaa agaaaactta gacatacttt atgaattagc tgaaattata ggtggagaag
     7861 tttctggttc tcgtgccact atagatgcag gttggttaga taaagcaaga caagttggtc
     7921 aaactggtaa aactgtaaga ccagaccttt atatagcatg tggtatatct ggagcaatac
     7981 aacatatagc tggtatggaa gatgctgagt ttatagttgc tataaataaa aatccagaag
     8041 ctccaatatt taaatatgct gatgttggta tagttggaga tgttcataaa gtgcttccag
     8101 aacttatcag tcagttaagt gttgcaaaag aaaaaggtga agttttagct aactaatttc
     8161 ttggggaggg tattatgagt acaagtgatg ttaaagttta tgagaatgta gctgttgaag
     8221 tagatggaaa tatatgtaca gtgaaaatga atagacctaa agcccttaat gcaataaatt
     8281 caaagacttt agaagaactt tatgaagtat ttgtagatat taataatgat gaaactattg
     8341 atgttgtaat attgacaggg gaaggaaagg catttgtagc tggagcagat attgcataca
     8401 tgaaagattt agatgctgta gctgctaaag attttagtat cttaggagca aaagcttttg
     8461 gagaaataga aaatagtaaa aaagtagtga tagctgctgt aaatggattt gctttaggtg
     8521 gaggatgtga acttgcaatg gcatgtgata taagaattgc atcttctaaa gctaaatttg
     8581 gtcagccaga agtaactctt ggaataactc caggatatgg aggaactcaa aggcttacaa
     8641 gattggttgg aatggcaaaa gcaaaagaat taatctttac aggtcaagtt ataaaagctg
     8701 atgaagctga aaaaataggg ctagtaaata gagtcgttga gccagacatt ttaatagaag
     8761 aagttgagaa attagctaag ataatagcta aaaatgctca gcttgcagtt agatactcta
     8821 aagaagcaat acaacttggt gctcaaactg atataaatac tggaatagat atagaatcta
     8881 atttatttgg tctttgtttt tcaactaaag accaaaaaga aggaatgtca gctttcgttg
     8941 aaaagagaga agctaacttt ataaaagggt aaaaatctaa ttaaaaatat atttgctgtt
     9001 aactagatta aatagtattt taatctagtt aacagaatat aaatactaaa ataacaggag
     9061 gttataacta tgaaattagc tgtaataggt agtggaacta tgggaagtgg tattgtacaa
     9121 acttttgcaa gttgtggaca tgatgtatgt ttaaagagta gaactcaagg tgctatagat
     9181 aaatgtttag ctttattaga taaaaattta actaagttag ttactaaggg aaaaatggat
     9241 gaagctacaa aagcagaaat attaagtcat gttagttcaa ctactaacta tgaagattta
     9301 aaagatatgg atttaataat agaagcatct gtagaagaca tgaatataaa gaaagatgtt
     9361 ttcaagttac tagatgaatt atgtaaagaa gatactatct tggcaacaaa tacttcgtca
     9421 ttatctataa cagaaatagc ttcttctact aagagaccag ataaagttat aggaatgcat
     9481 ttctttaatc cagttcctat gatgaaatta gttgaagtta taagtggtca gttaacatca
     9541 aaagttactt ttgatacagt atttgaatta tctaagagta tcaataaagt accagtagat
     9601 gtatctgaat ctcctggatt tgtagtaaat agaatactta tacctatgat aaatgaagct
     9661 gttggtatat atgcagatgg tgttgcaagt aaagaagaaa tagatgaagc tatgaaatta
     9721 ggagcaaacc atccaatggg accactagca ttaggtgatt taatcggatt agatgttgtt
     9781 ttagctataa tgaacgtttt atatactgag tttggagata ctaaatatag acctcatcca
     9841 cttttagcta aaatggttag agctaatcaa ttaggaagaa aaactaagat aggattctat
     9901 gattataata aataagaatt tgggaattaa aagtttaaat aaaattgttt aaaaaacaat
     9961 ttcggatata tgaaaaatct aatttaatgg gggtaatgaa tatgagagaa gtagtaattg
    10021 ccagtgcagc tagaacagca gtaggaagtt ttggaggagc atttaaatca gtttcagcgg
    10081 tagagttagg ggtaacagca gctaaagaag ctataaaaag agctaacata actccagata
    10141 tgatagatga atctctttta gggggagtac ttacagcagg tcttggacaa aatatagcaa
    10201 gacaaatagc attaggagca ggaataccag tagaaaaacc agctatgact ataaatatag
    10261 tttgtggttc tggattaaga tctgtttcaa tggcatctca acttatagca ttaggtgatg
    10321 ctgatataat gttagttggt ggagctgaaa acatgagtat gtctccttat ttagtaccaa
    10381 gtgcgagata tggtgcaaga atgggtgatg ctgcttttgt tgattcaatg ataaaagatg
    10441 gattatcaga catatttaat aactatcaca tgggtattac tgctgaaaac atagcagagc
    10501 aatggaatat aactagagaa gaacaagatg aattagctct tgcaagtcaa aataaagctg
    10561 aaaaagctca agctgaagga aaatttgatg aagaaatagt tcctgttgtt ataaaaggaa
    10621 gaaaaggtga cactgtagta gataaagatg aatatattaa gcctggcact acaatggaga
    10681 aacttgctaa gttaagacct gcatttaaaa aagatggaac agttactgct ggtaatgcat
    10741 caggaataaa tgatggtgct gctatgctag tagtaatggc taaagaaaaa gctgaagaac
    10801 taggaataga gcctcttgca actatagttt cttatggaac agctggtgtt gaccctaaaa
    10861 taatgggata tggaccagtt ccagcaacta aaaaagcttt agaagctgct aatatgacta
    10921 ttgaagatat agatttagtt gaagctaatg aggcatttgc tgcccaatct gtagctgtaa
    10981 taagagactt aaatatagat atgaataaag ttaatgttaa tggtggagca atagctatag
    11041 gacatccaat aggatgctca ggagcaagaa tacttactac acttttatat gaaatgaaga
    11101 gaagagatgc taaaactggt cttgctacac tttgtatagg tggtggaatg ggaactactt
    11161 taatagttaa gagatagttt tagattataa tatttacaaa ttaaatattt aattatgaat
    11221 ttaacctgta agaataacaa atagttattc ttacaggttt ttatagttaa aaataattat
    11281 tatctattaa acaaaaatag tgtaaaatat ataatatcat gattttgaag atataaaaaa
    11341 gtaggaagat ataaaagaaa gtaggtaaaa gtttgtttaa aaaagagaat caaagatata
    11401 atcttatatc gtatacaaat gaagaagaaa tgactttaaa agaagtttta ttggacaagc
    11461 taaatttctc agttaggtca ttatcaaaaa tgaagaggga aaagagtgtt ttagtaaatg
    11521 gagtatataa aaaaccgagt ttaaaggtgt atagtggtga tttaatagaa gtaaaaatat
    11581 acgaggaaaa agcaaatttt gaacctcaag atttaaattt acagataatt tatgatgatt
    11641 ttgatataat tatggtgaat aaacctccgt ttatggtagt tcacccaaca aaaagccact
    11701 atgataaaac aatagcaaat ggtattagtt actatataga taatcaaaaa gaaaacgtaa
    11761 aaataagatt tgtaaatagg ttagatatga atacttcagg gttagttata gtagcaaaaa
    11821 atgcttatgc acatcatact ttgtctacag caatgagtga aaataaagtt gaaaaaaagt
    11881 atataacagt agttgatgga attataaaag aaaatgaggg aactatagat gagccaattt
    11941 atagacctac agaagattca ataaagagga taatagatga aagaggacag tcatctgtta
    12001 ctcactataa agtaatagaa agactagaaa atgcaactgt attagaagta agcttagaaa
    12061 ctggtagaac acatcaaata agagtacata tggctcatat aggtcatgga ataataggtg
    12121 atgagttgta tggttatgta gatgaagagc taataaatag gcaagcactt catgcatata
    12181 agttagagtt tgaacaacca agaacaaaag aaaaattgaa atttaaagca gatataccag
    12241 aggatatgaa agagttaata tcgaaattaa gataatgggg tgatatatat gataatacat
    12301 aaatttataa tacatgtttt ggacaaaaat agtgatgttc caatattaaa tgactttgaa
    12361 ggcaaagtta atcaagaagt agatggtttt ttccagaaag ctataaaaag aattgcaaaa
    12421 gatgaggatt taagaaaagg tgtttttaaa gattataatg acaatttaat taaaaactgt
    12481 tgtgaacaaa taatatatga tgaaagtact tttttgaaaa attctaaaga aattgcatct
    12541 tacttgtttg atgttatgaa aattaatgct gcactagaat cttgtgattt ggcaatttgc
    12601 ttatacacta ttaaagatga aaagagtgta gcaatactga aattagatta taaaaagttg
    12661 tacactcatt caattgaatt tgtggatgat aaatttaata ttcaaatggt ttcaaatgaa
    12721 attggtatcc cagagacttt aagacaaaag caaggagctt tgattagtct aagtggtata
    12781 aatgatgagt ttcatctaag gcttttagat aaggatgctg aaaaagaagg gtcagaatct
    12841 aagtttgtaa cagaattttt aaatgctaaa aaaatagatg atgataagta caagaccaag
    12901 gtatttaaaa atacagctga aaattggata accaatgctc ttagtaatga tataaagcaa
    12961 gctgaagatg taagaagtat attaaattat acactgaagg aaaaacatga agttgatata
    13021 aatgactttg ttgataattc aattaaagat gatgagttaa aggatagctt taaagagcat
    13081 atggaagaaa aaggtcttga tgaaagtttt agtatagata aaaaatgggt tgagaaaaag
    13141 cttaaaaaaa gaagtataaa aacggataat ggttttgaca taaaagggaa tctaactgat
    13201 tttgaagacc caatgaagta tactgtaaaa caaaatcaag atggaactat agatataata
    13261 ataaagaatg ttacgtttta tgaagaaaag taatttatat acttagtata taaattaaat
    13321 ataagagcgt gtattttata tattgtaaat aaatgtaatc tagtctgtgc gaactctaat
    13381 ataatttatt atgtagaagt ttacacagac tatttatatt tgtagacaaa acgatactat
    13441 ttgttttctt cgatatattt acatatatca ccaatacatt taaagttctc agcttcctcg
    13501 tctggtattt ctattccaaa ttcatcttca agggccatta taatttcaac agcatctaat
    13561 gaatcagctt ctaagtcgtc cattaaagat gcttccatag ttatctcatc taaattgtct
    13621 acccctaatt gttctgctat tatttctttt attttctcaa acattttaag cctcctaaag
    13681 cagttttaat taattttaat gttagtttaa tataatatca agaatttttc aatatggaat
    13741 ctataaaaaa taataaaatt ttataaatgt agtaataaag tattatttga tgaataaact
    13801 ttattgataa caaatataac ttaggaggaa atgctatgaa atatgtagga ctattactaa
    13861 cttcagtagg aatgttttta cttatagcag taaattttta ttataattca ataactttag
    13921 atatgcaacg tatagaggat tatgtaatgg agaccaattt aatccttgaa gatgtagctg
    13981 aaaaggagag ttatgtatct aatgaaaaag aagactacat atcaaggtta atgcatgtaa
    14041 agaaaggaat agaaaattca aaaacatcct tcttgataga aagatataag gagtacaaaa
    14101 taaaatcaat agaaagttta atctatacta tatcagagga gaaaaaagat tatctggatg
    14161 aagttgatag atacaataaa cttggtgaaa aagaaataaa taaactaatc aataaaaact
    14221 ttttagaagt aacttatctg tctattacta catatattta attaaagaga caaaacttag
    14281 tctcttaatg attcaaggag gattagttat gacaaaatta gaagacaata tggaacgttt
    14341 ctttggagga tgcgaaggat tttttgggaa taaaatgttg ataataatag ttatagtatt
    14401 cttactatta tgcacagaca ttttagaaga cttattatgc gatgacaata tatggatatg
    14461 ggttatatta atagtattgt tattatttaa cttcgatgat ggttgttgtt gctaaaaaat
    14521 attgattatt aaataggtaa aaccagtaac ttatacaagt tatggtttta ccttttttag
    14581 ttcaaattaa aaaatttaaa aaaatagtaa aaatacatta gcaaaatgga aaccaaatgc
    14641 atagtatatg ttaggagcga aaagctcaac aaaatatcaa caggaggtaa cgtataatgt
    14701 tagatagatt ctttggagaa gaaggatgtt ttggtggagg aggatggtgg ataatagtac
    14761 tattcttcct attcttagct tttggagata gctgggcaga atttgacata atggcatgga
    14821 taccattcct aatagtttta ttaatacttt gctgctgtgg tggatgctta gaataagaac
    14881 acagttatta aaaaaaggag ggctttgtta tgttagatag attttttgga gaagaaggat
    14941 gctttggagg aggaggatgg tggataatag tactattctt cctattctta gcttttgaag
    15001 attgctggag agacattgac ataatgtcat ggataccttt cttaatatta ttgctaataa
    15061 cttgttcatg tggtggattc tttgatggtg aagtaggttg cggctgctaa tacttaaatc
    15121 attagaataa aaaaatgctg gtattttata ccagcatttt tttattttat tttttaatat
    15181 gatttaaatt aagaatgaat attattaaat ttgttgaata tagggtataa tataaaatat
    15241 aatgtattta aatgtacttg cttttatggt aaaataaaaa cttatataaa tgtagttaaa
    15301 ataggaacct tcaaaaattt ggttcagttt tagataaatt tagtaaaata aggaggatga
    15361 agatgaaagg caatataacg ataaaagatg ttgctaaaca agcaggagtg tcaatatcta
    15421 ctgtatctag agttataaat gattcaaaac ctgtaactga tgaagtcaaa caaaaagttt
    15481 tagaggttat aaaagagact ggatatatac caaatccact tgctagaagc ttagtaacaa
    15541 agaagagtca attaataggg gtaatagttc cagaagtttc agattctttt gttaatgagg
    15601 tgttaaatgg gatagaagag gttgctaaaa tgtatgacta tgatattctt ttagcgaata
    15661 catactctga taaggaacaa gaacttaaga gtataaatct attgagagca aaacaagtgg
    15721 aaggtatagt tatgatttca tggatagttg aacaagaaca tatcaactat atacaaaatt
    15781 gtggaatacc agcgacatat ataagtaaaa ctgctagaaa ttatgatata tatacagtaa
    15841 gtactagcaa cgaagaagct acttttgata tgacagagca tcttataaag aaaggtcatg
    15901 aaaagatagc ttttataatg acgagtaaag atgatactgt tttagaaatg gaaagacttg
    15961 ctggttatga gaaagcactt tcaaataaca atatagaatt agacaagagt ttgattaagt
    16021 atggtggaac tgattatgag agtggataca atagtatgaa agaactatta gatgatggaa
    16081 taatacctca tgcggctttt gtaacaggtg atgaggctgc cataggtgct ataaatgcta
    16141 tatgtgatgc tggatataag gttccagaag acatatctgt tgcaggattt aatgatgtta
    16201 agatagctag aatgtataga cctaaactta ctacagtata tcaacctcta tacgatatgg
    16261 gagcagtagc aataagaatg gttataaaat taataaataa ggaattaatt gaaaataaga
    16321 aaatagaatt accttataga attgttgata gagaaagtgt tacagaaaga aaaaaataaa
    16381 actattaaaa tcaatcaggt agtgcctaag gcactacctg attttttatg tcaataatat
    16441 caaatttaat aacagattaa ctaaaaataa ttatctaatt acttaaatag tttattttta
    16501 tctattcatg agggttagac tttttagttt tcttaaataa acttttagat tttttttgtt
    16561 gactacctgg tgtatttttt ggtgcaggtg aatttgactt acctttagta ggtttagcct
    16621 tcttagtttt agctggttta gtatctcttt ggttttctgc atctgagatt ttttccatta
    16681 tattatccag ttttttgcgt tgattttcat ctaaaaatgc tttgaatttt gatactactt
    16741 catctctgcc atctaggttc ttacctattt ttataagttc ctccataagt tcattttctg
    16801 attttccttt gtaactatca gccatctttt ctattttatc cttgtcaata tttttttgtt
    16861 tagccatttt ttctaatgac tctgtatcta attttttcat aaaaaaaccc ctttctataa
    16921 atatatattg aattatattc atactattta tatatagaaa taatattgaa gtggtgaatt
    16981 gtgagtgata tataatataa ataaaaattc ttatagataa tatatatgca ctgagcttta
    17041 aaaatggaac attaaaatat gaaaaacata ctttaatata gggcaattat ataatataag
    17101 ggggaattgt cttgaataac ttactatttt tgattggagt gattgcattg agtaatggta
    17161 atatctctat atttgatgat aaaaataaat caaaaggaaa taatagagtt agaaaaaaca
    17221 aaaaaaatgc aaatgataaa ctttcacagt ctacacatgg caatttaagg tttgatgcaa
    17281 atgatataaa aagaggttta aggctcatgg atttaagtga agaagattta gaaatgggaa
    17341 tggaaataat aacaagaact aaaaaataca tgtcaagaga tgaaagaaaa atactaataa
    17401 aaatagaaag tgttttagat ttagttagag gaataaaaaa attaaataat atagatatgg
    17461 tagatacaga agatgaaacg gattttttca gaaaaatgga tagtgatgat aaaaagaata
    17521 tgatgataaa ggaaattata gatgtattcc cagaaaaaag aaaaaattca gttgaaaaag
    17581 ctataggaat gaaaaagaag atagatttat ttgcagaatt atttttacca gatgactttg
    17641 gtgaaggtgg atttagtttg agctctttgg caaatataaa caatcttggt agtatgaata
    17701 atctcaaatt attaggaagt cttttaagag gtgatgatag taataatgat gatgaagaca
    17761 ataatgatga gttaaattat gaagacgaag aattagattg tgaagacaaa gaattggatt
    17821 atgatgatga gttaacagat gaaggtgaaa tggaggataa tgaagatgaa ttagtagaag
    17881 ataagaacac aggctatgaa aatatagaaa atgatgaaga tatagtatat gatgaggaac
    17941 tatacaacat taatgagcaa gaatccgaat acaattataa tgaaaaaaat actaaaacta
    18001 gagctaagaa aaaacgataa ttaactaaat acataaagaa aaaaggaaga aaaagtaatg
    18061 atagaataag attatctcaa ttactatata aaaccacttt aaaaaattca aaatttatta
    18121 tataataata atatgaaatc ctgaaacata cgataaggct tttttaaatt caacctacaa
    18181 atgaaatacg ggagaccgtg tctggtaaat tataacatgc ctagttagtt tggacgttaa
    18241 aggttactgg caagtcaccc acctgggagt gcctagggtg tgaatttact tagccaccgg
    18301 tgtttcggga caaaaaaagt gctactattt caaatagtag tacttttttt attaatatgc
    18361 atttttctac taaatacgcc taattattga taaattcaaa aagcaagtaa caattaagat
    18421 tataaaagca tagtattaat taggcttcaa aaagccaaag acttaataag aatcgcttac
    18481 agggagggca atgaaaaatg caagattata aaaaaaataa aagaagaatg atgaatcagc
    18541 caatgtctac aatgaatgaa gaagaagtgt atacagatga aataaattca gaagacatga
    18601 gaggttttaa aaaatcacac catcataatg gatgtaatac tgataataag tgtgagtgcc
    18661 atgatgattg caatccatgc aacccatgta atccatgtaa acctaaccca tgcaatccat
    18721 gcaaacctaa tccatgtgat gacaattgtg gatgccatga caattgtaaa tgtgattgtg
    18781 aaccatgtga aatggattca gatgaatgtt ttgaaaacaa atgtggacca gaatgctgta
    18841 atcctatatc tccaagaaac ttctctgtat caaatgcagt gccatttgca atagaggcta
    18901 atagaatatt tgatactatg caattccaaa catttacaga tgcaacagga ccaaatggag
    18961 agccattaac ttttgaaaca gaagtagtag aagtatttgg ttcagttcca agtgcaggtc
    19021 aagcaagtgt aactatagaa aaaatatgct taagtaatga tggaatagtt atagacacag
    19081 gaatgacaac tttagaagat ttcgatttag acccattagg agatatagta ggaagaaact
    19141 gtgaaacaac ttttgaattt gcagtttgtg gagaaagaaa ctctgagtgc tgtagacaag
    19201 gaaaaggcaa atcagtagct tataaacaaa gaggattaac tgtagcagtt cgcaatttag
    19261 tactagagct aagaggtaga tgtggatgta cagagttcgt tgcattagct ttcccagcag
    19321 ttagagcagg aggtggatgt aagagaagag ttgattatgt agaatttact tttaacacac
    19381 tttcagcacc aatatgcttg ccagctgacg gaagagctgt tactttaaga caagaatatc
    19441 aaactaactt aactgtagat tgtataggaa aatctatatt aaaattagaa tgcaacgaat
    19501 gttgtgaacc tttctatgaa ttaattatac caaatgatat agatttagta ctttgcttac
    19561 aagaaacagt tagcacatta ataagtgaac aaatagtagt tttagcatca ccaaatccaa
    19621 tccaaccaag acttgttgat actttctcta aagtatgtga tttttcgcaa tgtggaccta
    19681 atcatggaag tggaaagcca agttgccaca gatagatagg tagatatata gacagtttaa
    19741 attataaata aaaatcatct aaggaaggct accaaagtgt ataatttaca ttggtagcct
    19801 tcacgttttt ataactagcg tatagatttt agtgatttaa aaagcactat agtatgtaat
    19861 agacaagtaa agattgatac tatcgtcatt gtgtatatgt atgcataaat attaagtcct
    19921 ggaattggaa gaaatacata taaagctatt agttgaatta acatgccagt aatagtattt
    19981 atacttgaag ctaattcttt tcttattgaa tgtaaaatgc cagatagagt ttgatttagg
    20041 gacataaata gtggaactaa aaacatagct tttagatatt ctcctgcaag tgtattttta
    20101 aatactaata tacataaatc ttttccaaag aaataaaaaa atattgatga tagtatgcct
    20161 acaaataaag taagaagtat ggagtatttg atttttttaa ttacactctt acgctttctt
    20221 agagccattt cttgtgaaat agttggtatt aaatttacaa taagcgctga accaacagta
    20281 aaaggtaaaa atataaaagg cattaccatc ccactgacaa taccatacat acttaaagat
    20341 tgttgataag tcattcctga taatgctaat cttgatggta tcatcataga acttatagat
    20401 tgcaaaagta tgtttgacat tctattacaa gttatgggaa tagacatttt taatgtttcc
    20461 atagaagaat tataaaaatc ttttatgctt ataatatacc tattgtcaaa tgatgaatct
    20521 cgccataagc aaataagcat aaatataata ttactcaact caccaatcga tatacctaat
    20581 agagctatat aacaattcat agatttatta tttatgtaca taacaagtaa aaaaacaaat
    20641 aatattttac caatttgttc aatgatttgt ccaatagcag ggatttttac attctttatg
    20701 ccatagtaat atcctcttag tacgtttgaa agagttatta taactatagc aggacaaaca
    20761 gctagtataa atagatttaa tttagcatct tttaaaaatt taagtgataa aaaagaacta
    20821 ttgaaagatg caactataga tataattagt gctacgaaaa atgatatata taaagttgat
    20881 ataaataaag cattagtatt gtgtctatcg tttaaagctt ttctctttgc aactagacaa
    20941 ctaagtgcag taggtatacc tgttgttgta acagctaagc aaatcatcaa aaagttaaaa
    21001 atcatatgat agatacctaa acctgtttca cctagtgctc ttgataagaa tattttatat
    21061 aaaaaaccaa atattcttac aataaaattg gatataaata aaataactgt tgatagtact
    21121 aaataaggta ctttcaaaaa aatcacctcc ttatctttta aatatattca caaggaggtg
    21181 taaaaattta taattttata aattctggtt tcaatttatt aaatttagat acatatttaa
    21241 atcccatatt ttttagtaat gaatatatgt agtcaaactc acatgcaact tgacttatat
    21301 gatgtgaatc tgaacctgtg gttatgattt cccctcccaa gtctttgtac atttgaagta
    21361 tatacttaga tggggttagg tctggaagat tatatctata acaagaggta tttatctcga
    21421 tacctttgcc atcataaata gcttgtttaa gagtttcttc aattatatca gaaaatagtc
    21481 tatcatctaa aatagtgtca taaggtgcat accttttaat caaatctaaa tgacctaaga
    21541 cagagtaatc tttataattc ttaacaatat tatataaata aagatagtaa ttttcataaa
    21601 cttcatgttg agttttatct ttaaaataat taccaaggta taagtccatt gtatctatag
    21661 catggataga acatattata aagtccaatg gatattgatg tgcttccttt ttgtatgtat
    21721 ccattaattg agtttgaact ccaaattcaa ttcctttttt tattgatatt ttatctttat
    21781 atttgctttg aagagtctct aaactcttaa aataatcttc gtagacaatt gaaaaagaat
    21841 catcagcata tacatcatag tcaacatggt ctgtgaaaca aatttcctcc aaaccgagtt
    21901 caatagattt ttttaccatt tcttccattg tagattttcc gtctgtagag aaacttgagt
    21961 gcatgtgata gtcgtaaaac ataaatattt ccccttttta taaaaatttt ggtattatat
    22021 atacatacta aataatatca aatatacata aaagcatcaa taaaatataa atacaatgag
    22081 cggtgataaa tttggaaaaa tacagaatag atttaaatga gaaaaaatca actaaatata
    22141 tacagatatt taatcatata aaagaattga taataaataa agagttagta gaacatgaaa
    22201 aattgcctcc aataagaaaa ctatcaaatt ttttacaagt aaataacact actatagtta
    22261 aggtatacga gcttttagaa aatgaaggat atgtatataa aattataggg agtggtactt
    22321 ttgtatcaag tttaaattct tataaaagcg gtatagataa caggaaaaat aagattattg
    22381 tgcaaagaga agatttaatt cattttgaca atgggaatcc atctaatgat atgtttccta
    22441 tcgattcatt taaaaatgct gtaaatatgg cattatctaa agatggtagt tcaatatttg
    22501 aatatgatga aggtcttggc tctgaagaat taagagaaaa aatggtagag tatctaagtg
    22561 atggaaatat aaaaactact aaggaaaata ttcaaataat atcaggtgct caacaaggta
    22621 tagatatagt ttgtaaagga cttataagtt attcagatgt tgtttttatg gaagaacctt
    22681 cttacaatgg agcaattgaa gtgtttaaaa gtagaggtgc aaaaataata tctataccta
    22741 tgttagatga tggaattgat ataggtattt taaaattaaa gttggaaaaa ataaaaccaa
    22801 gacttatata cattatgcct aattttcaaa atccaactgg aatatcttac tcaacatata
    22861 aaaaaaagaa attgatagaa ttggcagaag aacatgattt ttatataata gaagatgatt
    22921 ttataagtga ttttgttttt gaatcaaagg acaatagaac aattagaagt tatgatgata
    22981 aaaatagagt agtatatata aaaagctttt caaaaatact tatgccaggt cttaggatag
    23041 gaattgtaga aatgccaaat gagttgttaa aaaaagtttt atgggctaaa tattcatcag
    23101 atatatcaac accaggttta attcaaaaat caatgtatta ctatatgaat aattttgatt
    23161 ggaagaatta tttgagtcat atagaaaaga tatatactga taagtataaa ttggcaaaaa
    23221 acttgattaa tgacaaattg agtggtaaat taaaagttag aaaatcttgt ggaggaataa
    23281 actttttttt agaattacca agaggatata catctcaagc atttacaaat tttatgttaa
    23341 acaaaggagt gtcaatgctt ccagggactt atttttttga caatctagtg gatgatagat
    23401 tctttaggat aaatatagct cgcccaagca tggaagaact agaaaaggga atatctataa
    23461 taagtgataa tatagatgag tttttttgtg aatataaaaa caagttagat ataaaaagca
    23521 ataaattatt ttattaaata aatagaggtt ttttaggagg aaaaaatgtt tgacaagaag
    23581 aaattagata ggattaatga attagcaaag aaaaataaag agggaatcct ttctgctgat
    23641 gaaatcaaag aaagagaaat tttaaggaaa gaatatttag aaaactttag agcccacttt
    23701 agatcaagac tagatagtgt caaagtagtt tcaccagaag aatatgagca atacatgaaa
    23761 aacaataaaa attagaactt agtaggagga aaatatgaac ttaaagtacg aatttaagaa
    23821 tgcttgggat tttgaaagaa aagaaaatac tattgaacaa attatgcaat attctagcaa
    23881 ttatatggag tttttaagta agtcaaagac tgaaagactt tcagtaaaag aaattataaa
    23941 attggctaaa gaaaataact atatttcaat agatgaagct atggaaaaag gaagcataag
    24001 ttgtggtgat aagatttatg ttataaataa agagaaggca gtagcacttt ttgtaatagg
    24061 taaaaattat atagaaaaag gtatgaagat tataggaagc catatagatt cgccaagatt
    24121 agatttaaaa ccaaatccac tgtatcaaga gagtaatcta ggttttttta agactcatta
    24181 ttatggtgga ataaaaaaat accaatggac ggctattcca cttgctttac atggtatagt
    24241 tatattaaat gatggaacaa aagtggacat atctattggg gaagaagata gtgacccagt
    24301 attttgtgta actgatttat tgattcattt ggctggagac caaatgcaaa agaaactatc
    24361 agaaggaatt agtggagaag ctttaaatat attaattgga aatatgcctt tagaagatga
    24421 agaaaaagaa cctataacag caaatatatt aaagatttta aatgagaaat acaatatagt
    24481 tgaagaagat ttattaagtg ctgaaattga agtagttcca gctggtaagg ctagagattt
    24541 agggcttgat aggtctatgg tgttgggata tgggcatgat gatagggtat gttcatatgc
    24601 tgctgtaaaa gctatactag aaactgaaca accagaattt acttcagttg cattatgtgt
    24661 agataaagaa gaaattggtt ctaaagggaa tacaggtatg cactcaaagt tttttgaaaa
    24721 tactgtggct gaactgattg ctttagaagg agattattgt gatattaaag taagaagagc
    24781 tttagcaaat agtaaggtat tatcagctga tgtttctgct ggatatgacc caaattttgg
    24841 agaagcatat gaaaagagaa attcggcata tatgggaaat ggagtagttt taactaagta
    24901 tacaggttca agaggaaaga gtggatgtaa tgatgctaat gctgaattta tgtcagaagt
    24961 aaagagaatt tttaataaag gaaatgtagt atggcaaact gctgaacttg gaaaagtaga
    25021 ccaaggagga ggcggaacta tagcccatat attggcaaat caaggtgcag aggttataga
    25081 ctgtggtgtt ggagttttaa atatgcatgc accacatgag attgtctcta aagtagacat
    25141 atatgaaatg tataagggat ataaggcatt ttttaatata aatttataag taaaaatata
    25201 aatgtaataa gtgaataaag gctgttgtat aaacaattta atctgttgta caacagtctt
    25261 atttttatgt aaaaatagca atttgtcaca ctagagaaaa taaaagaaaa tactgtcaaa
    25321 ttaaaaatta tttaaaaaaa aattgacaac gatttcatct tgttataata tgtaataaag
    25381 aacttgttat ataatgttat aaaaatgtta catagggagg tgagcaaaat ggatgaaaag
    25441 agacaaaaaa aagaaatgga tttagaagta aattcctttg ttcctttata tcaacaacta
    25501 tatgacaaca taaaaaaaca aatagcatct ggcatatata aaccaggaga taaacttcca
    25561 tctgaaggag acttatgtaa agaatttaat ataagtcgta taactgtgag aaatgcactt
    25621 aatgaacttg taaaagaaga tatattatgt aaaaaacgtg gtaaagggac ttatgtaaca
    25681 ataccagaga gaatagaagc aacatgtgca ggaaatagtt ttactaattc ttgtcatcgt
    25741 attaatgcaa aaccaagtac caaaataatc tctgttttaa taaaaaaagc agataagcaa
    25801 gtagctgaag ctttaagtat tgaactagaa gagaaggtaa tatgtattaa aagacttaga
    25861 ttaatagatg aagtacctgt tatttttgaa gttgactatt ttagaataga ttacatgttt
    25921 ttattaaaag aagaattaga agataaatct ttaatggagg ttatatctaa taatataagc
    25981 acattaccta aacgagtaga aaatatattt gaagtaaaac attcaaacaa agaatattct
    26041 gaccatctta aatgtgcaag taatatgcca ctattgaaag taagacaatc ggtgtataca
    26101 gaaaataatg atgtcttata ttacaatgag caatttataa gaagtgataa gtacaaatat
    26161 gcagtatcag cagaaatata atctataatt tagtaggagg atgagtatga aaaagataat
    26221 attagcatct catggagact tttcaaaagg gcttttaaat gcagtaaaaa tgatagtagg
    26281 agatttagca gattgtgtca gttcgtatgg tttgtaccct ggacaaagtg cttcagattt
    26341 tgctttagaa ttagaaaaaa caatatcaga agataaagaa tgtgaatata taattttatc
    26401 tgacttatat ggagcaagtg tatgtacagc aatgttaaga ttaactaatc tacataatgt
    26461 taggttattt tctggaatga atttgaatat ggtattagaa cttcttacaa ggttttctga
    26521 tgaattaaca gttgaagata tagaccaatt agtggaagaa tctagaagag gaatacaaag
    26581 cgtgacatta caaattaaag aagaagaaga ggtattttag tttatgaaaa aaaagggaat
    26641 attatcagta tttaaaagta aaaaaccaat tatagcaatg atacacttaa aaggagatac
    26701 tccagaagat atctttgaaa gagctaaaaa agagattaca atctttgaag aaaatggtgt
    26761 agatggaata atgttagaaa attactatgg taattattat gatttagaaa gaatacttga
    26821 atatgtatca aaagctaatt tatcaatacc atatggagta aactgtttaa atgttgatac
    26881 tatgggattt gaactggcaa caaaatataa tgctagttat atacaggttg attctgtagt
    26941 aggtcatgtt aaacctagag atgaagctac tttagaagag ttttttaaat tacaacgttc
    27001 aaaatgccca gcgtatttaa ttggaggcgt acgttttaaa tatcagccag tattatcaga
    27061 aaatgatgtt gaagaagatt taaaaatagg aatgacaaga tgtgatgcta tagcagttac
    27121 agaaaatgct acaggtcaag aaacatcaat ggaaaaaata gaactgtttc gtaaaaattt
    27181 aggagacttc ccattggtta tagctgctgg agttacatta gaaaatgcaa aaaaacagct
    27241 taaattagga gatatggcaa taataggaag ttactttaaa gataattaca aagattttgg
    27301 ggatgttagt gtagaacacg taaaaacatt catggatgaa atcaaaaaaa ttagggagga
    27361 attataatga ttaaattagt aagagtagac cacagactta tacatggaca agtagcattt
    27421 acatggacaa agtttttaag cacagactgt atattgatag caagtgatga cttattaaaa
    27481 gatgaattga gaatggcagg acttaaaatg gctaaaccat ctaatgttaa gttagtaatg
    27541 aaaagcatag cagattctat aaaagcactt aactcaggtg ttactgataa atacaactta
    27601 ttgatacttt gtgaatctgt agaagatgtt tatagacttg ctaaagaggt aaaagctatt
    27661 aaatctataa accttggtgg aacaaaatca gatgataatc gtgaaaatat atctaaagca
    27721 gtgcatgtat caaaagatga tataaagatg attaaagagt tagattcaga aggcgtaaat
    27781 gtatttgtac aattagttcc tgatgatgat gctacaaatg taatgaaatt aatataattt
    27841 tagggggatg aaaatggaat ttacacaagt tattttgata actctaattg cattctttgc
    27901 atatatgcat agttttgtag gttctacaat gcataataga cctatagttg ttgcaccact
    27961 tgttggttta gcactaggta atcttcatac aggtatagta ataggttcaa cattagaatt
    28021 agtatttatg ggtgcatttc ctgttggggc aagtaatcct cctgattttg tgtctggttc
    28081 tattattgcc acagcgtttg taatattaac gggtcaagat gtatcagcag cagttgtact
    28141 tgcagttcct atagcaactc tagtattgct tatagataac ttcttaatga cagtagtact
    28201 tacatgggga gctcatattg ctgaccgtta tgcagaagag gggaatattg aaggcgtaga
    28261 acgtgtgcaa ttattatttg gtataggaaa taaattaata ttagcaataa tagtaggtat
    28321 aggattttca ttaggtgttc cagtaataga aaaaatactt tcatttatac catcatatgt
    28381 aactcatgga atggatgttg cagcaggcgt gattcctgca ataggttttg ccatgttagc
    28441 tagaatgatg cttaataaga aaacagtagc atttttatta ttaggattta tattggttgc
    28501 ttacctaaac ataacagtaa caggagttgc attgtttgga ttagcaatag ctttaatata
    28561 tgttaacttt gtaggagaga aggaggtaat agtagatgac aacgagttct aagaaattag
    28621 agacaatttc accagatagt aaaataacga ggaaagactt ttggaaatgt tttagaaggt
    28681 cattgacatt agattcatct tggaactacg aacgtatgca aaatatagca tatgcataca
    28741 tgatggcacc aataatccgt agattatata aagatgataa agaaaagaaa tctaaggctt
    28801 taaaaagaca tttagaattt atgtcagtta ctcctcatat aagtactctt ttggtaggta
    28861 tatctggagc tatggaagaa gaaaatgcaa agaataaaga atttgatgct aatagtataa
    28921 atgctgttaa atcaagttta atgggtccag tttctgggat aggagattca tttttctggg
    28981 gaacattaaa gcttatagca gctggggttg gtatagcttt agcttctcag ggtaacataa
    29041 tgggaccgat tttattcctt ttaataataa atgttcctca ttttattata cgctatatat
    29101 gtctagataa aggatttaag tatggaactc aattctttaa agatgtgagt ggttcaagta
    29161 tagtttcaaa agttatggaa gcagcttcaa tgttagggct tatggtaatt ggtggtatga
    29221 ctgcatctaa tgtaatgtta aaacttagtg ttaatgtagg tagtggagaa tgggcagagc
    29281 ctattcagac ttacttagac caaataatgc catgtatgct tccagctatg atattcggta
    29341 ttatgtattg gttattagga aaaaaggtaa agacaactac gatattaatt tcagttatga
    29401 ttatttgtat agtattggct gctattggag tagtataaat aaaaaaatcc caagttcatt
    29461 tgaacgaggg attttttgac taaattaaat aaaaaagaaa gaaggttcat aataatttat
    29521 aagcatttat gtgatagtta taattagctt attaattagt tataaactca aaattaagca
    29581 ctactttatt aaagttatta tattataatt tcgaaatact cacataatct gtttagaaat
    29641 ttatcttcta atggggaaaa agttttcttt ttagagtaaa tgaagaaaaa ctttctagta
    29701 aaatcaacat cctttatttt ataacatttt attttacctg cattgagata atcgatagct
    29761 gaaatgtacg atataaagga cactccaaga cctaatctaa ccatttcctt aatagcctca
    29821 tttgattcta catgagcgat tacatttaat ttacttactg gaaagttatt tttactaagt
    29881 gtgtttagta ttaagtttct tgtacctgac ccttcttttc tcataataaa atttagataa
    29941 gccaattctc ctatatcgat acaattattt ttattatcaa ttttaaaatc tgaaggagtg
    30001 ataagaacaa gttcatcatc taataagtct aggtactcta tttgaggatt attgatttta
    30061 gaaccaacta atccaaagct tattcgttca tttaaaattt ctgatatagc atattgagaa
    30121 tcataatggc ttatggaaaa ttttacatct ggataactca tagaaaaact cttcataaaa
    30181 tcaggtaaaa tataagtttc aggtatggaa ctacatgcta tatctatgat accttctatt
    30241 tttcctgaat attcttttat atcataaatt gcacgtttgc aattattcaa tatatatata
    30301 gcatgttcat aaagaatttc accagatttt gtgagtgtaa taactttgtt gcttctattt
    30361 ataagaacag tttctagctc tctctctaaa ttctgtatgt gtgcgcttac agtaggttga
    30421 gttaaaaaaa gttctcttgc agcctttgaa aaactctgat gttttgcaac agcaacaaat
    30481 acttcaagtt gtttaaaatc cattatttaa tcctccttaa attatctaaa actattataa
    30541 catatttgat aaattaatag tcaaaggtga tttttaaaat agaaaacctt taaatattca
    30601 tggagttttt gattgtttag gaataatttg gtataatgtt gtaaggtact tacaataaaa
    30661 atatcgtaaa ttgaattttc aaaattcaac tttaaagtgt tttttattac agaaaaatta
    30721 caattagctt cttaatctta ttaaattcaa ataaatatta
//
LOCUS       DAEPXW010000044        30656 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.045, whole genome shotgun sequence.
ACCESSION   DAEPXW010000044 DAEPXW010000000
VERSION     DAEPXW010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30656
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.045"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            121..2022
                     /locus_tag="KRM55_001986"
     CDS             121..2022
                     /locus_tag="KRM55_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1594230.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            2025..3068
                     /gene="ypdE"
                     /locus_tag="KRM55_001987"
     CDS             2025..3068
                     /gene="ypdE"
                     /locus_tag="KRM55_001987"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1594231.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            3083..3388
                     /locus_tag="KRM55_001988"
     CDS             3083..3388
                     /locus_tag="KRM55_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1594232.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            3485..3820
                     /locus_tag="KRM55_001989"
     CDS             3485..3820
                     /locus_tag="KRM55_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1594233.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            3852..5174
                     /locus_tag="KRM55_001990"
     CDS             3852..5174
                     /locus_tag="KRM55_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1594234.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            5184..6254
                     /locus_tag="KRM55_001991"
     CDS             5184..6254
                     /locus_tag="KRM55_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1594235.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            6259..7446
                     /locus_tag="KRM55_001992"
     CDS             6259..7446
                     /locus_tag="KRM55_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1594236.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(7643..8515)
                     /locus_tag="KRM55_001993"
     CDS             complement(7643..8515)
                     /locus_tag="KRM55_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBH1594237.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNVLWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(8909..9100)
                     /locus_tag="KRM55_001994"
     CDS             complement(8909..9100)
                     /locus_tag="KRM55_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594238.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            9320..10366
                     /gene="cobT"
                     /locus_tag="KRM55_001995"
     CDS             9320..10366
                     /gene="cobT"
                     /locus_tag="KRM55_001995"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBH1594239.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            10398..10958
                     /gene="cobU"
                     /locus_tag="KRM55_001996"
     CDS             10398..10958
                     /gene="cobU"
                     /locus_tag="KRM55_001996"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBH1594240.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            10968..11741
                     /gene="cobS"
                     /locus_tag="KRM55_001997"
     CDS             10968..11741
                     /gene="cobS"
                     /locus_tag="KRM55_001997"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBH1594241.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            11761..12375
                     /locus_tag="KRM55_001998"
     CDS             11761..12375
                     /locus_tag="KRM55_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH1594242.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      12442..12621
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            12751..14250
                     /locus_tag="KRM55_001999"
     CDS             12751..14250
                     /locus_tag="KRM55_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBH1594243.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            14289..15665
                     /locus_tag="KRM55_002000"
     CDS             14289..15665
                     /locus_tag="KRM55_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBH1594244.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNK"
     gene            15666..16637
                     /locus_tag="KRM55_002001"
     CDS             15666..16637
                     /locus_tag="KRM55_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH1594245.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            16669..17739
                     /locus_tag="KRM55_002002"
     CDS             16669..17739
                     /locus_tag="KRM55_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1594246.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTSLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            17741..18628
                     /locus_tag="KRM55_002003"
     CDS             17741..18628
                     /locus_tag="KRM55_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH1594247.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKYMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            18616..19248
                     /locus_tag="KRM55_002004"
     CDS             18616..19248
                     /locus_tag="KRM55_002004"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBH1594248.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            19257..20483
                     /locus_tag="KRM55_002005"
     CDS             19257..20483
                     /locus_tag="KRM55_002005"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBH1594249.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDDGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            20480..21088
                     /locus_tag="KRM55_002006"
     CDS             20480..21088
                     /locus_tag="KRM55_002006"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBH1594250.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            21078..21653
                     /locus_tag="KRM55_002007"
     CDS             21078..21653
                     /locus_tag="KRM55_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBH1594251.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            21646..22398
                     /locus_tag="KRM55_002008"
     CDS             21646..22398
                     /locus_tag="KRM55_002008"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBH1594252.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            22382..23503
                     /gene="cbiG"
                     /locus_tag="KRM55_002009"
     CDS             22382..23503
                     /gene="cbiG"
                     /locus_tag="KRM55_002009"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBH1594253.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSIIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNAYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTQKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNTDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            23500..24225
                     /gene="cobJ"
                     /locus_tag="KRM55_002010"
     CDS             23500..24225
                     /gene="cobJ"
                     /locus_tag="KRM55_002010"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBH1594254.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            24222..24974
                     /gene="cobK"
                     /locus_tag="KRM55_002011"
     CDS             24222..24974
                     /gene="cobK"
                     /locus_tag="KRM55_002011"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBH1594255.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            24993..26471
                     /locus_tag="KRM55_002012"
     CDS             24993..26471
                     /locus_tag="KRM55_002012"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBH1594256.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFDVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            26501..27406
                     /gene="hemC"
                     /locus_tag="KRM55_002013"
     CDS             26501..27406
                     /gene="hemC"
                     /locus_tag="KRM55_002013"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBH1594257.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            27396..28895
                     /gene="cobA"
                     /locus_tag="KRM55_002014"
     CDS             27396..28895
                     /gene="cobA"
                     /locus_tag="KRM55_002014"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBH1594258.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELVPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            28912..29877
                     /gene="hemB"
                     /locus_tag="KRM55_002015"
     CDS             28912..29877
                     /gene="hemB"
                     /locus_tag="KRM55_002015"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBH1594259.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            30030..30608
                     /locus_tag="KRM55_002016"
     CDS             30030..30608
                     /locus_tag="KRM55_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBH1594260.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCRAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNVLVTLDLEELKKFDI"
BASE COUNT        12410 a         3054 c         5671 g         9521 t
ORIGIN      
        1 gtggaattaa aatatactag gatataaaat tcttaaataa aaagaaaagg ttgtttttat
       61 aaaaaatatt ttttatacca ctttaaaaaa cacaataata acactgaggg aggtggggat
      121 atgagagaac gcattattct tgaaacatta aaaaatagta gtggttatct aaacatagat
      181 tattttgcag ataagttggg ggtatctact cgaactatca gaaatgaaat aaaaaagata
      241 gaaactataa aagaatgtaa tggttttaaa ttagaatata agtctaaatt aggatatatt
      301 ctaaatatta aagaccaaga taaattcgag cattatctaa gaaacttacc ctcagattta
      361 gttgaaaatc cagaacaacg gttggagtct ataatagtag agcttttagt aaatgaaggt
      421 tataaaacta tagaacagtt aagtaaaaaa tttctagtaa gttcatccca aataaaaaat
      481 gatttaaaaa agatagatga aaagataaag gatacagaat taaaactaga gcgaaaggct
      541 cattatggaa ttaaaataga aggttctata aaagaaattc aaagtatatt ggtggatagt
      601 tattttagag ggaatagaaa tataacagag tacaggaata agtttataga taatttaaaa
      661 ttagctaata ttagaagtac aataaaaaat gtacttaatg aacatgattt agaagcaaat
      721 ttaacagaac ttgaggaaat attagcacaa attattatat tgtatataag agttagtatg
      781 agagtagtgg gaaatgctag cgatttaaaa ttatatacag aagatttaat tatagataaa
      841 ttattagata aaatttttag agataaaaaa tataacctta attatgatga aaagtattat
      901 ttaaaggagc ttataaaact aaagactaaa gataagaaag ccactataaa gaatattgat
      961 aagaataaac ttcaagatat tatgttcgaa ttttttagag agatagataa aaaatataac
     1021 tctaattttt tagaagataa agagtttttt aacttatttt acttacatat tgcatgttta
     1081 atagaacgta taaagaagaa ccacaagata ataaatcctt tttcagttaa aataagtcaa
     1141 cagtatccaa ctgtttttaa tttatctatt caattttcaa aaatcataga aaatgagtat
     1201 catataaaaa taagtcaaga tgaaataggg tttatagcta ctcacattgc tgttcctttt
     1261 gaaaagagag aagaagctaa ttttaataaa aaatataaaa tagcaataat atgctcttct
     1321 ggtggaggta gtgcattttt gataaattta agacttaaag aaatttttcc aaatgctgag
     1381 ataagaaatt tttcattact agaagaaaaa gctgtaatag aatttgcacc agatttgatt
     1441 ttttcaataa caaatctttt atttgaaata aatgctccag ttatacttat aaatgaaatt
     1501 ttagacgaat tggattattt agatattaaa gaaagtgtta gatttgcaga ccatatagga
     1561 aatatatcaa gcccaaaaca atatatatta ggtctatttg ataagaatca ctttaggtgt
     1621 ataaaagata aagctaagta taaggatatc cttgatagta tgtcaaaatg tatagttgac
     1681 gagggagctt gttctccaac ctatcccaaa gatgtatggg aaagagaaag ttatttgagt
     1741 actatttata caaatggggt ggctatacct catccaatcg agatgacagg aaacaaaaat
     1801 ataatatcag tagctttgat acaaactgat attatttatg aaaatagggt gcctaaaatt
     1861 attttcatga tttcattaat aaagggaaat ttagaacttc ataagcaaat atctaaatat
     1921 ttaagtaaga ttatggcaaa taaggatatg gtagacatgc taaataagtc acaatcttat
     1981 gaagagttta tgtataagtt aaaaatctat ctgggaggtt agacatgaat atagagtttt
     2041 ttaagaggtt gtcagaagca gatggtatag catctaatga agaagaggtt agacatgttt
     2101 tattggaaga actaaaagct tatagtgata aaattatctg tgatgggcta gggagtatca
     2161 tcttttctaa aataaaagat gagagtgcac caaacgtaat gatttgtgct catatggatg
     2221 aagttggatt tatggtgaga agtatagaca aacttggtat gattcactta ataacaatag
     2281 gaggagtaaa acctcttgca cagtttgtac aaaaagttag aattacaaca aaagaaggga
     2341 agaaaatccc cgctgtcata aatgctacat ataataatgg taaggctgaa aatatatatg
     2401 cagatattgg agcatataca gaagaagatg tatataacct agggattaat gttggggata
     2461 tggtaacata tacaacaagc tttgaggaat ttactttacc agaccgatta gtgggaaagg
     2521 cttttgatga taggatagga tgttttgtga tgggagaagt tttaaaagaa cttaggaaag
     2581 aaaatctaaa ttgtaatatt cactttgcgg ctacaagtag tgaagaggtt ggaataaggg
     2641 gagcaaagac atcaacacag ttaataaatc cagatatagt atttgtaata gatgtagcat
     2701 gtgctaaaaa tgagtttgtg agagactata caaatcagaa acaaattgat aaaggtgtaa
     2761 tgctaatgca tagagatagg actctagtcc ctagtagaaa aatgatagat tatgtaatgg
     2821 aaattgctga taaaaataat ataccacttc aacatgatat gtttgaatca ggtgggactg
     2881 atggaggaga agcacatctc gtaaatgaag ggaaaccttg tgtagtaact tgtgtaccag
     2941 ttagatatgg tcattgtgca ttttcaatag taagtaataa agatttggag aacattataa
     3001 gattgtatac acagttaatt ttaaattttg atgaagaaca atataaacat ataagaaatt
     3061 ttatctaaag gagaataaga aaatgtcaac agaagtacaa ataatggaac ttatatcaac
     3121 tgcaggagag agtaaatcga aagcttttga ggctttaaaa aaagtgaagt caaaagattt
     3181 taaaggagca aaattgttaa tagaggaggc tcgtaaaata gatattgaag ctcacaggat
     3241 acaaacagaa ttaataactc aagatttaaa tgaagatgtt gaaagtccag caatgagtct
     3301 tttaatggta catgctcaag accactatat gacttctcag ctagcaaaag acttgataga
     3361 ggctttgata tattgtctcg ataagtaatt gtaatgtaga aatagattat ttatgtaaaa
     3421 attcttttaa aagtttagat acttttaaga gataataaaa atacaaactt taggaggaat
     3481 tattatgaaa atattattat gttgtgcagg tggattttct actaatatgt taatgcaaaa
     3541 tatgaaaaag gtggtaaaag agagtgctaa actcaatgaa aaagattttg agtttacagc
     3601 tataccagca gattcaatag aaagtgaagt tgatgattgg gatatagtac ttataggtcc
     3661 tcaaatagct cacaaaatag acttcttaaa aggaatatta gagccaaaaa ataagccttt
     3721 tgcagtaata gataaagatg tatatggaaa aatggatgga gctacagtta tgaagttggc
     3781 attaataact tataagaaac atcaattagc tcaaggataa taaaaataat gagggaaaag
     3841 ggagattaga tatgttttca aaatttgaag catttatgaa tagagtattt atgcctttag
     3901 ctcataaggt tgacaatcaa cgtcaccttg gttctataaa ggctggtatg gttgctatga
     3961 caccattcac aatattagga agtatatttg caatacttcc agcacttcca aatatgcttg
     4021 gagaaaataa tccaataagc aaattcatac ttaacaattc agcaatattg gatttaccag
     4081 taagtctttc cataggttta ataggattat atgcttgtat gtgtattgct tttaatctgg
     4141 ggaactacta taaattatat ataccaggtt gtgttgcact atcaactttt tcttttttat
     4201 tcctagtagc ctcatttaca ccagatggag ctttagaaat aggaaattta ggagctaaag
     4261 ggctatttac aggtatgata gcagggcttg gttctgtgga gttatataat ttttgtaata
     4321 agaagaatat cacaataaaa atgccagaaa atgtacctga ttttgtatct aggtcttttg
     4381 aattaatacc tactactata atagtttgtg gaacttttat agttgctcgt tttatttcat
     4441 taaaagtatt tggagaatta cctccacaga tacttactca atttttatct ccattagtag
     4501 gaagtatgga taacccatgg tcagttcttg cacttaactt tgctatatgt actatattct
     4561 tttttggaat acattcatca gtatttagtc ctataactag acctataatg attacattta
     4621 tagctgaaaa catagcagct atgcaagctg gagaaacaat acctcatttc tttacagcag
     4681 gagcttcaag tgcattcttt ggatttacag gatgtggaat tagtataggt tgtgtaattg
     4741 catgtatgtt atcaaaaaat gcttcctata agaagattgg acgtgtatca ttattccctg
     4801 cattatttgg gataaatgaa ccaatattat ttggagcacc gataatatta aatccaataa
     4861 tgtttatacc acatgtattt ggtggagcta taataggtac actaccaatg ttttttatgc
     4921 actggggatg gttagcaaag ccagtatttg accctccata tgtaggggta ttcttagaag
     4981 gatttttaac taatggagat tggcattcta tattagcaaa tgcattgcaa ttagtattag
     5041 cagttttatt atattggcca ttctttaaaa taatggaacg tcaacaaaat aataaaaaac
     5101 aaaaagaaga aactaagaat atattctcta aagaagaaga agacttattg gatgatttag
     5161 gattggattt ctaatatttt gttatgaata atacaatgga gagattagta tccttaatct
     5221 ataaaagagg tgttgacgct cttttgatta aagcaaaaaa tactaaaaga tatataggag
     5281 ctttatcagg tagtggtgta tatgtgcttg ttactaagga taaaaattat caaattctag
     5341 atggcagata tattgatgaa gcagataaaa aaacgactgg tttcataaaa aggattgtat
     5401 ctcaaggttc ttatatacca actataattg agttattaaa agaattaaat ataaaaaagt
     5461 tagcaataga aaaccaagct atgagtatac aagagtatct ttcactaaaa aatgaaggtt
     5521 ttgaaatcaa tttaataaca aatgaattat ggaagctaag ggctataaaa tctaaagaag
     5581 aaattgaact tattaaaaag gcttgtgaaa ttacagatga agtatttgat gaggttattt
     5641 ctgaaattaa aaaagatatg actgagctag aagtatcagc tctaattcag tatcatgcat
     5701 taaaaaaagg tgcaagtgga atgtcttttg aaacaatagt ggtatcagga gaaagaggtg
     5761 caatgccaca tggaagacct acaaacaaaa aattgaaagt gaatgaagct ataacaatag
     5821 attttggtgt tgtttatcaa gggtatcaat cagacatgac tcgtacaata tctataggta
     5881 aacctcctaa aattattaaa gagatatatg atgtagtatt ggaagcacaa ttatctgcaa
     5941 tagagtcaat aaaggaagga actagggcaa gtgatgttga caaagtggct agaaaaatta
     6001 tagataaaca tggatttggc gaatatttta atcatggact gggtcatggt ataggtcttg
     6061 gagatggtga agttcccact ttaaatccaa atagtgaaga tatattagtg gaaggaatgg
     6121 taatgtcttg tgagccaggt atttatattc caaatgtagg gggagttaga atagaagatg
     6181 atattgttat aatagatgga aaaggtgttc cactcaataa gacatccaaa gagtttataa
     6241 tattaggaga gtaaaattat gaaatataat tttaataaag tattaaatcg taaagaagga
     6301 aattgtagaa aatggagcaa ccatgtgatt aaagaaaaat ttggcttaaa tgaagatgca
     6361 attcctatgg atttagctga tatcgatttt gagtgtgctc ctgctataaa agaatctatc
     6421 ttaaaaagag catcagtagg agattatagt tatactttta taggagatga cttctatgat
     6481 gctattataa attggaataa aagaagattt gatgtatata tagaaaagga ttggataaaa
     6541 ttaacttttg gtactgtttc aacccttcat tatatagtcc aagcatatac taaagaagga
     6601 gagggtgtat tgataaatac acctgcttat gacccttttg cagaggctgt agtaaataat
     6661 aatagaaagt tgtgttgtag ctcattaaaa ttagataaca atagatatta tttagattta
     6721 gaggatatgg aaaatcaaat gaaatacgag aatataagat tgcttatatt ctgtagtcca
     6781 caaaatccat caggtcgtat atggacaaaa gaagaactat atcaagtgtc agagttatgt
     6841 ttaaagtata atgtaatttt ggtaagtgat gaaattcata gagatataat atttaaagat
     6901 tatagatttg tatctttgtg gaatgctcat ccagaaattt ataaaaatag tataatctgt
     6961 gtatctccta ataaaggctt caacttaggt ggattaaaaa catcatatgt attaataaga
     7021 gatgtaaaaa ttagggagac tttattagaa aggctaaaaa gtaattcaat aacttctcca
     7081 aatgtatttg caataccagc aatagttgca gcatataatg aaagcgaaga atggctagat
     7141 gctatgacta gttatgtaga ggagaatttt gaaatagttt atgatttctt tgaaactaat
     7201 ataccaaaag ctaaagtgat gaagtcagac tcttcttttt tagcctggat agatgtaaga
     7261 gaagtattta gaaatgaaga agaatctaaa gaatttttta gacatgcaaa cttaactatg
     7321 gtagttggaa gttattttgt gaaagatgga gatggattta ttcgtattaa tgtggggtgt
     7381 cctagagaaa cattaaatga ggctctaaat agaatcaaaa aaacgtatat aagtatgtat
     7441 tgttaaatca taaaaaaagt atctatggtt tatataaaaa cacattattt agttatcaaa
     7501 tattactgga attttgtatt ccagtaatat tttttgatta aggaatatta ttgaggaata
     7561 ttaaataata ttatttcata cccttatatt aacttatata aaaatatttt attattttgg
     7621 gaacgggtta gctaaccttt atctagtgta tatttatatt gtaagaagca gtaaaaactt
     7681 ttcctttact aagtttatta ataaacttct tatctttata aattttgtta gaatttatac
     7741 tatcagcaag accataccaa ggttctatac ataaaaaagg agcagtagaa ttagtttcac
     7801 tataataagg agtccaaata ccaactagag ggaaatcttc catagatata gttacatatt
     7861 tactaccatc attattacat atagacactt catctatgtt ggtgtatatc aaagcatcat
     7921 tcttgaatac ttctggattt aactgtaagt tttttaattt tccaataggt attatatcat
     7981 ctgtaaaaga accatttaaa ttgatttttt ctacatcatt tttactttta aactcaaggt
     8041 agtgtttaga aaaatcattt tgttcgtaaa aaggaaggtt gaatgcagga tgtccaccta
     8101 tagaaaagaa tatatcttta gaatcagtat tttttacaat ccattctacc tcaatactat
     8161 tatcatttaa tgtatagttt atgattagct caaaagaata tggatacttc tttaaagtag
     8221 attcattatc tgttaattta taagttacaa atgtatctcc tttatctaca atctcaaagt
     8281 ccatatctct agcaaaccca tgttgagtca tgctatataa attttcttct attattgttt
     8341 cattatcaaa aagtttacct actataggga acaatatagg tgattgtcta ccccaatatt
     8401 ttttattacc atcccaaaga acgtttttgt cgtatttttt agaaaatatt ttagttagtt
     8461 cagcaccaaa actgcttgat tcgataatta aattttcatt ttgtaatata ttcatttaaa
     8521 atctccttta ttatatttta tgagtatatt atactataaa gtataaagat tattaaattt
     8581 tatttgatat tatatttgaa aggtagattt tagtatattt tgaaaatttt gttttgaaaa
     8641 tttgggatta tttaagaaat tttgtattat aaatagaagg aaatagataa attgtataga
     8701 ataaaatata ttaagataag ttaataatgt taaatgggaa gtgagtttat ggaaaaacca
     8761 aatacaaaag ttgttaactt tcaagagtat aaagacagaa aaaaccaaag agaagtaaat
     8821 agagacgaac ttttaaagct tataaaaaaa attgtgactt caaaataggg agttgttaaa
     8881 ctccctattt taatgggttt cataataatt aagacattct aagtccatct atataatctt
     8941 tgaattgtga gaaatctgat tcactactta attctatggt ttctgaacct tccgtataaa
     9001 aattcttaag atagatagta taattattat caacacaatc atgataaata catctatatc
     9061 catcttcata caaacttttt aatttagaaa aatcatccac aatatcatct ccttaaagtt
     9121 cttttaaata tatttttaca aaaagcatct aattgtatgc aaattgacaa tgtaaaataa
     9181 aggaaatgaa cataaaatgt agaataattt ttatatgtat gtaaaaataa aaagaaaaag
     9241 ttgaaatttt tagaaaataa gagtattttt tatctaaaaa gagagtttaa aaaataaaaa
     9301 aatgttggga ggataaaaaa tgagtttatt agaaagtata tcaaaaaaca tatattccct
     9361 agataactct tctattgaaa aaacaaagca gagattggat aggcttatac atccaactgg
     9421 aagcttagga aagatagaag atatttgcat gcaattagca ggaatatttg gcaatgaaaa
     9481 ttttgacaca agtaaaaagg ttataattgc ttttgcggga gaccatggtg tatatgaaga
     9541 aggcgtagca cctgaccctc aaaatataac aaaattacag tttccaaatt tttcgaaagg
     9601 tctatgtgga gttggagtaa taagtaaatt tgtaggggca gatgttgtag ctgtagatgt
     9661 aggaataaac tgtgatgaaa aactggatgg ggtattagac tacaagataa gaaaagggac
     9721 atcaaatatg gcaaaaggtc cagctatgag taaacaagaa gcaattagat gtttagagat
     9781 aggtattgaa atagcagagc agtgtataga aaaagattat aaggttattg gtattgggga
     9841 gatgggtata gcaaatacta ctccaagtac agcaataata tctgtaattt cagggtgtga
     9901 cccgttagaa gttactggta taggtgcagg tcttaagaaa gaaagactaa agcataaggc
     9961 tgaagtaatt agaaaggcta ttgaaattaa taatccaaat ccaactgatg gagtagatat
    10021 tttatctaaa gtaggaggat ttgaaatagg ctcaatggca ggtgttatat taggttgtag
    10081 tgctaatagg attccagtag taattgatgg gtttatttct tatgcagcag cattaattgc
    10141 atataagata aatccaaaaa ctagagaata tatgatagca tctcatttat cagcagaatc
    10201 aggaactaaa agagcattag acatattaaa attagaccct ctattaaata tggatatgag
    10261 attaggtgag ggaagtggag ctgctttagc atttgatata atagaagctt caaactatac
    10321 ttataaaaat atggcaactt ttgatgaaat tgacatggga agataaatat aaaaatttaa
    10381 tatgtaggag tgttttgatg agtaaaatta ttctagtaac aggaggagct aggtcaggga
    10441 agagtaactt tgcagaaaaa ctatgttttg acagaaataa taatacagct tatatagcaa
    10501 cctctattcc atttgatgat gaaatgaaag atagagtaaa aaaacatcaa gagaatagac
    10561 ctagaaactg gaatacttat gaaatatatg aagatatata ttccataatt aaggagatat
    10621 ataaagaaca tgaaactgtt atactagatt gtgtaacatt attagtaaat aatctaatgt
    10681 ttgaacacaa tttaaatata gaagaatcta gtcaagaaga aataaacaaa ttagaacaat
    10741 acataaaaga acaagttgtc aaacttattg aagaaataga aaaaacaaat ctatactttg
    10801 tatttgtaac gaatgagtta ggtatgggaa ttgttcctgg gaataaactt agtagaattt
    10861 atgctgatat tgtaggtcgt ataaatcaat atatagcttc gaaaagtaat gaagtttatt
    10921 ttgtagttag tggcatagct atgaagataa aggagtagta tgcaattatg aaaagattta
    10981 ttttaatact acagtttttg acaaggatac ctataaaatt aaatgtagga tttgatgatg
    11041 aattttataa gtcaatagta tattttccac ttgtaggttt tgtcataggt atattatcct
    11101 atttaatagg atggatttct atgcttttat ttgaaccatt tatagcttct ataataataa
    11161 ctctagctgg tgtcttaatt actggaggac ttcatataga tggattagga gatacatttg
    11221 atgcaatata tagttataga gataaagaaa aaatgcttga aataatgaaa gattcaagat
    11281 taggtacaaa ttcacttcta gcaattatgt ttgtactttt attaaaggtt ggattcgttt
    11341 acgatataat aagtaataat tcattgtggg ttataatttt tatgccaatg attgcaaggt
    11401 taggagtaat gttattgaca tataaaactg tgacaccaag agaaaaagga atgggaaatt
    11461 tatttatagg aaaattaact acaagtatgt taataactgc tataatatac acattattga
    11521 tagttgctct tattactaaa tttatatttt tattacctaa tatagtgttg attaaagtat
    11581 taggttcgat tatagtggtt tttgtattta taatattatt caaaaaacat atttataaaa
    11641 aaattgatgg agtaacagga gatatattag gctgtggaat agaactttca gagcttgtat
    11701 atttaattta catatatttg ttaattttta tgttttttta aagtaaaaag tggtgataat
    11761 atgataagat taatattaat aagacatgca ctgacaaatg ataataaaaa aggaagatta
    11821 tcaggccata taaatagttg tattagtgaa gagggcaaac tacaaataaa taaaattacc
    11881 agatatctga gtaatgaaaa catagataag gtttatacaa caccatctac acgtactaaa
    11941 gatacagtag aaaaaatatc aaaattgaaa ttattagaaa tagaagaaaa agaagcttta
    12001 agagaaatta gttttggaga ctttgaagga agaacttttg aagaaattaa aatcaaatat
    12061 ccaaatgagt ttgaaaaaat gataaaagaa ggtaacaact atagatatcc aaatggagaa
    12121 agtttgatag actcttataa aagagtggca aaagaaattg ataatataat tttagaaaat
    12181 gatagtaatt tagatacaaa gacaatactt atatgttctc atgcaggaac aataagaaat
    12241 ataataacac atttgatttc tggtagttat aagtatcact ggaactttaa aattgataat
    12301 gcatctatta cagttttaga aattgatggt ggatttgctg taatagataa aatgaatttt
    12361 acagacttca tataatttaa tcaaaaccaa acattacaat ctgtgtttgt aatatatctg
    12421 taaaattagc aatgaaaata gaatattaga ttaaaattag gttcttaatt agatgttaaa
    12481 agggaaaaag gttagatgcc tttgcagccc ccgctactgt gaaaccaacg aaactataaa
    12541 taccactgtc agtttgatgg gaaggttata gaagtaggat gaagttaagc caggatacct
    12601 gcctaattta atttaaaaca agaggtcttc ggggtgaaag atttttaatt aatatatata
    12661 aaagtcctat ctttagaagt attaggactt tttttaattt gttttttagt aaattttaac
    12721 aaggagggat ggaaagtggg gaaaaaaata atgctacaag gaacagcttc aaatgtaggt
    12781 aaaagtgtct tagtagcagg tttgtgtaga atatttaagc aagatggtta tactgttgct
    12841 ccttttaagt cacaaaatat ggctttaaat tcttttataa ctaaagaagg attagaaatg
    12901 ggaagagcac aagtatttca agcagaggct gcgaaaatag agccaatagc tgatatgaat
    12961 ccagttttat taaaaccttc tggaaataat aaaagtcaag ttattgtaag aggtaaagtt
    13021 gtaggagaaa tgccttcttc taagtatcat gattataaat tggagttagt agatgtgttg
    13081 aaggaaacat ttaatagctt aaattcaagg tatgatattg tagttatgga aggggcagga
    13141 agtaatgcag agataaactt aaaagataga gatatctcta atatgggtat ggcagaaata
    13201 gctgatgcac ctgtaataat agtcggagat attgatagag gaggcgtatt tgcctcatta
    13261 gcaggaacaa tgcttttatt aaatgaagat gagaaaagaa gagtcaaagg tgtaataatc
    13321 aataaattta gaggaaaaaa agagctttta caagatggtg taaagatgct agaagacatc
    13381 ataaaagtac ctgttatagg agtagtacct tatacagata taaaaataga agatgaagac
    13441 agtgtaacta cgagatttaa gaaaaaaatg aataaaagtg atatacacat agaaataatt
    13501 agaaccccac atatgtcaaa ttttacagat tttaatatat ttgagacaca agaagatgta
    13561 agtattagat atgtagacta tggagaatct ttaggaaatc cagatatatt aataatacct
    13621 ggaactaaaa gtactataga cgatttaaca tatataagaa aaagtggtct tgaatcgcaa
    13681 atcaaaaatt tacatagtca aggtaaattg atatttggga tatgtggtgg ataccaaatg
    13741 ttaggtaaaa aattaaaaga cccttatcat gttgaaagtg aaattgaaga agttgatgga
    13801 ataggtcttt tagatacaga aacaacgttt gagaaagaaa agactacaac acaagtagaa
    13861 gctactattg ttgaatgtat cagtgaatac atgaataacc ttaagggaaa aaaagtaaaa
    13921 ggttatgaaa ttcatatggg aattacaaag cgaggtaatg atgtaagaag tttagattta
    13981 ataactaaaa aacttgataa agaagtgaat tatactgagg gaagtgtaaa taaagagggg
    14041 aatgtaattg ggacttatct tcatgggata tttgatgaaa taagctttac aagagcaatt
    14101 ttaaacaata taagaaagaa aaaaggttta ggagaattag aaagcaaagt aaactctttt
    14161 aatgaattta aggataaaga gtatgataag ttggctgatt ttttaagaga acatttagat
    14221 atagagaaaa tatatgagat tatgaaataa tgatgacttt tatttataat ttaggtagga
    14281 ggtgtattat gaaaaaaatt ttaattgcgg gtactaatag tggagtaggt aaaacaacaa
    14341 tatcattagg aataatgcaa gctttggtta agagaaatat gaaagtacag ccatataaag
    14401 tagggccaga ctatatagac ccttcatatc acacttttat aactggaaga cattctagaa
    14461 atttagattc ttatatgtta gatgatgaaa aaataaagta tatagtaaat aagtcctcaa
    14521 aagatgcaga tatttcagta atagaaggtg ttatgggctt atatgatggc tttggaatag
    14581 atttagataa ttgtacaagt tcacatactt caaaggtatt aaagtcacct gttatattag
    14641 ttataaatgg taaatctatg gcagcatcta gtgctgctat ggtacttgga tataaggaac
    14701 tagataaaga tgtaaatata aagggtgtta tagtaaataa tgtaaagact aatagccatt
    14761 atcaaataat taagagttct atagaaaaat attgtaatgt tgaagtattg gggtattttc
    14821 ctccaaataa caaattctct ttggaatctc gacatctagg attagttcct agtgtagaaa
    14881 tgaaatcact aagggaaaaa ttttatacct tagcagatga aattgaacac tatatagata
    14941 ttgacagaat aattgaaata tcagaaagcg atgaatttga gagtgatttt gattttcaaa
    15001 ctttaataga aaataataaa ataaaagaac atgttaataa taaatcaata gctatagcat
    15061 atgataaagc attcaatttt tattatagag aaaatataga gcttttagag gaacttggtt
    15121 tagaaataaa ctattttagc cctcttgaag atgtatcagt gccaaatgca gattatattt
    15181 atattggagg aggttttcca gaaatatttg gaaaagaatt agaagcaaat gagtcaatga
    15241 gaacttccat attagaagca cataacaata atatacctat ttatgcagaa tgtggaggac
    15301 tgatgtacct aggtgagaaa ctattgaatc aagaagaaca agaatttaat atggttggaa
    15361 tatttagtgg aattagtaag atgacatctt ctttaaagag atttgggtac tgtattggtg
    15421 tagccaagga aaatactctt ttatctaaaa aaggggaatc tattaaaggg catgagtttc
    15481 atcattcaat atttgaaagt gatgaaaaat gtgtatattc aatgagaaaa gaaagagatg
    15541 gaaatatagt agaagagtgg gatggtggtt atagtaaagg aaacactttg gctacatatc
    15601 ttcatactca tttttataat aacttaaatt gtatagaaaa ttttttgaaa aaaggaaata
    15661 agtaaatgag tattttatct atttatatag gatatgtgac agacttaatt gtaggagacc
    15721 catattcttt tcctcatcca gtgagattta ttggtaaact tataaatttt actcaaggta
    15781 taataagaaa ggtctctaaa aatgataggc agttaaaatt tgggggattt atattatggt
    15841 ttataaccgt tggaataaca tatttaacaa cttatgctat agtgaagtta tttagtttta
    15901 atatattatt gagtattgta gtgaatagtt ttataattta tacaacacta gccacaaaat
    15961 gtttaaaaga cgaagcatta aaaatttata atgtattaaa aactgaagat atagaaaaat
    16021 ctaggattca gctatcttat atagtaggta gggatactac taatttaagt gaacctgaaa
    16081 taataagagc aactgtagaa actgttgcag aaaatactgt agatggtata attgcgccta
    16141 tgttttatgc atttattgga ggagcaccac ttgctatggc ctataaagct ataaatacat
    16201 tggactcaac agttggatat aaaaataaaa agtataaaga tattggtttt gcatctgcta
    16261 agattgatga tatagccaat tatataccag ctagaatatc tgtcattctt atgacaattg
    16321 gaagtttctt tttaaattat aactatagga actgttttaa aatctctatt agagatagaa
    16381 agaatcataa aagtccaaat tgtgcttttt cagaaggtgc agtatctggt gctctaggaa
    16441 tacaactagg aggtaccaac gtttattttg gggaaaaagt atataagcca acaatagggg
    16501 ataagcttag ggagatagat aaagaagata taattaaaac taataaaatt atgtatgcat
    16561 cttcatttgt atctatgttg gtatttacac taatatatgt gttatgtagg atgattttaa
    16621 ttaacttaat tatataaatt attgtttgtt aacttaaggg ggacatagat gaaggattta
    16681 gggcatggtg ccaatgtaga tgaaatggca agattatatg ggaaaaaccc aaaagaaata
    16741 attgatttta gttcaaacat aaatccaaat gtattaccaa atttagagag atacatttta
    16801 aaaggcttag aagagtgtag gaattatcca gatataaatt atacaagctt gagagaaaat
    16861 atatcaaaat atatagatat aaatccagac tttataatac ctggcaatgg tgcaacagaa
    16921 gtgatttatt tgcttatgaa gagtattaaa aaaaaattgg ctataataaa tccgactttt
    16981 tcagagtata gaagaagtgc tgagttaaat aatttagata ttatagattt agagttagat
    17041 ttagaaaata actttaaact taatatagat ataataaaag aaaatataaa aagatttgat
    17101 agtttattta tatgtaatcc taataatccg agtggtaatg tccaagattt aaaggaactt
    17161 gttcatttac tagataaaca taataaggta ctaataattg atgaaacttt catggaattt
    17221 gttgaagatg aaagtaaata tagtttggtt aaatatatag aatcaaataa aaatatattt
    17281 ataattaaag ctgtgactaa gttttttggt atgcctggtt taaggctagg atatggtctt
    17341 acaagcaaca ctgaaattat gaacaaaatt tatgaacaca aagagccatg gactatcaat
    17401 tcttttgcag atatactatc caattttatt tttgaagata aagagtatat taaaaatagt
    17461 aaagaatatt acatagaaga aagaaaatat atgttacaag agttgagaaa cataagaaat
    17521 ataaaggtct atgatacaga tgctaatttt atcttgataa gaatatataa aaaaacaact
    17581 aaagaattga aaaaagattt gtttaagcaa ggaaacatat tagttagaga tgcgtctaat
    17641 tttataggat tagatgatag ttttataaga gtggctataa aatctcatga agataacaaa
    17701 attcttatag aaaatatgaa aaatttattg ggtgattaaa atgaaatctt atggaatatg
    17761 cccagcatct tgtggagaat ttgtacaagg tataattgat gatgaagaat atttatgttc
    17821 atatgcaata gatatgtatt ctaaagtgta tattgaagaa aaattagtag atataaattt
    17881 agggagatat aagtcaaggt tagcaattga aaaggtattt gaaaaattta atttacctaa
    17941 aaaatatact aaaaatattt ctttaaatat aaatagtaaa atacctgttg gaaaaggaat
    18001 ggcaagttca actgctgata taggagctac tataaaggca acattatcat tgatagataa
    18061 agatttaagt agcgaggaga tttctaaatt agcagcagaa atagaaccaa cagattctat
    18121 atttatagat aaaaatagta tatttaatcc tctaaatgga actgttataa aatacctagg
    18181 aaatctgacc aatgctaaag ttgtaatact tgaaccaaac aaagtactag atactatgaa
    18241 aattagattg aggcaagatt ataataaatt aaaagtagag aataaagaag taataaaaaa
    18301 atcatttgct cttttagaag aaggattgaa aaaaaataat ttatctctag ttggagaggc
    18361 ttgtactttg agtagcttag caaatgagaa tatagaaaaa aaagagtatt taaatgaaat
    18421 aataaaaata tcaaaaaaat atggagcata tggagtaaat attgctcaca gtggaactgt
    18481 agtaggtatt ttaattgata agtatatgaa tgataaaaag atgatagatg ccttatgtga
    18541 atctaacata aattctgtct ataataaaat ttatacacaa aacataatta atggaggaat
    18601 taagggggaa atagaatgga atacataaag aatcctatga aaatagaaga aaaaagtttt
    18661 gaattgatac aagaaataat agacgaaatt agaccagatt ataaatttaa gaataatatc
    18721 gaagaaaaaa taataaaaag agctatacat actactgctg attttgatta cttagatata
    18781 ttaaaaatat cagaagaagc agttgatagt ataatagatg cattaaaaaa taatgcaagt
    18841 atttatactg atacaaatat ggctcttagt ggtataaata aaagaaagtt agaatcatta
    18901 ggatgtaagt ataaatgttt agtggcagat gatgaaactg taaaattagc taaagaaaaa
    18961 ggaattactc gttctatggc agcagtagaa attgcagcta aagaagaagg aagaaaaata
    19021 ttcgttttag gtaatgctcc aacagcttta tataaagtta tggagatgaa atcagaaggt
    19081 agattagatt tagatgcagt tataggagtt cctgtaggtt ttgtaggagc acaagaatca
    19141 aaagatgaag ttgaaaaaac agatatacca tatataattt ctaaaggtag aaaaggtggc
    19201 agtaatttag cagcagcaat agtaaatgct atattatata ctatgtaggt atctatatgg
    19261 aagaatatgt atatatagat ggaaaaaaat atagaagagg atatactaca ggttcatgtg
    19321 caacaggtgc atctaaggct gctgtatata tgttgattac aaaaaataga atcaatacta
    19381 taaatataga tactcctaag gggataccat tactactaaa agttgataat ataaatattt
    19441 ctgatacatt tgtggaatgt tccataaaaa aagatggtgg agatgatata gatgcaactc
    19501 ataccatgga tatttatgca agagctgaaa ttgtagctaa aaatgataag aacaaagggt
    19561 atcttactct aaaggatata gatagtttaa gcaccaatag tgagtgtaaa agtgagctct
    19621 ataagtttat tagggtttat ggcggaactg gtattggtgt ggttacaaaa aaaggtctta
    19681 gcgtggatgt tggtaaacct gctataaatc cgactccact taaaatgata aatcatgaaa
    19741 taagaaagct tataggagat aattttgaat ctatacttgg aaatgataaa gttttaaaaa
    19801 taacaatctt tgctccacaa ggagaaactg tagcaaaaaa aacatttaat ccaagattag
    19861 gtatagttgg aggaatatct ataataggta caactgggat tgttgaaccc atgagtgatg
    19921 atggttggaa gaagtctcta tctatagaac ttcagatgaa aaaagaacaa ggcttagata
    19981 aaataatatt ggttccagga aatcatggag aacagtttat aagagaaaaa ttaaacttag
    20041 atattaagta tgtagttagg gtaagtaatt ttataggcta tatgattaaa gaagctcaaa
    20101 gaataggata taaaaaaatc ttaatggcag gtcatatagg taaatttata aaagtatctg
    20161 ctggtatttt taatactcat agtaaggtag cagatgctag aagtgagata ttagtggcaa
    20221 acttagcttt aatgggagct agatacgaat ttttaaataa aataaatcaa tgcgtaacta
    20281 ctgaagaagc tgtagagcta ataaataata gtgaatatag agaagtatat aatatattaa
    20341 gtaataaatg tagggagaga gtaaagcaat acttgaatga agattcagat gatattgatg
    20401 tggaagtaat catattttca atggataagt ctttattagg taaatcggat aatacagatg
    20461 atttagtgga ggtctttata tgataaacat aataggtcta ggacctggta acttagacta
    20521 tataacaaaa aaaggtgaaa atttaatttc cacttctgat gtattaattg gtggtaaaag
    20581 aaatttagag tctataaaaa attttgaagg agaaaaaata gttctggatt ctaatttaag
    20641 agaaattata gagtacataa ataacaataa agaaaagcaa atatcaataa tagcatctgg
    20701 ggacccacta atatatggga taggtagata tctatctaaa aatattgata ataagatgtt
    20761 aaacatggtt tctgggatta gttcattaca gtacatattt tcaaaaatat atgtagatat
    20821 gaatgatgta tatattacaa gtagtcatgg taaagtacca gattttgatt acatattatc
    20881 acataaaaaa gtatgtatgg ttacagattc aaagatagga ccaaaacaaa taagtagaga
    20941 aataatagat agaaatctaa ataaaattat tgttgtagga gaaaatctgt catatgacaa
    21001 tgaaaaaata acaatagcaa aaccagaaga gataataaga atggacaatt ttgatatgaa
    21061 tgttgtggtg attttagatg aggaatagtg aatttataac aggtaaagtt ccaattacta
    21121 aggaagaggt tagagcaata tcaataagta agttaaattt agtaaatgct aaaaacctca
    21181 tagacatagg ggctggtaca ggaagtgtaa gtgttgaagc tgcatataat tatcctaatt
    21241 taaaggttat atctatagag aaaaatgatg atgctataga gcttatagag aaaaataaaa
    21301 aaaagttcaa cttaaaaaat atagaagtga taaaaggata tgctccaatt aatctagggt
    21361 taaatgttaa agttgagtct atttttcttg ggggaacagg aaataatctg gaagaaataa
    21421 tagaatggtc taaaaaaaat ctcgttacag gaggaagact tgtagctaat tttataataa
    21481 tagatacatt taatcaaact ttaaaactgc ttaaaaagca tggatttaaa gaaatagatg
    21541 tatgtgtttt gaatgtttct aaactagaga aactaggaaa aggtgaatat tttaaaccac
    21601 taaatcctat atatataata tcttgtgaaa aaggggaaaa tgatgatgaa taaagtacat
    21661 tttgtaggag caggacctgg agataaagag ctgataacat taaaaggata caaattatta
    21721 agtaatgcag atgtagtgat atatgcaggt tcacttgtta atcctgaact tttggaatac
    21781 tgtaaagaag attgccaaat acataatagt gcacatatgg atttacaaga gataatagat
    21841 gttatgagag aaggtataga aaataataaa tctgttgtaa gactgcaaac aggtgatttt
    21901 tctatatatg gttcaattag agaacaagtg gaagatttaa ataaattgaa tatagattat
    21961 gactgtactc caggagtaag ttctttttta ggggcagcat catctttagg ggttgaatat
    22021 acagttccag aaatttctca aagtgtaatt ataacaagaa tggaaggcag aactccggtt
    22081 ccagagaaag aatcaataca atcatatgct aagcatcaga catctatggt aatattttta
    22141 tctgttcaag aaattgagaa agttgtgtct aaattactgg aaggtggata tccaaaagat
    22201 actcctatag cagttatata caaagcaact tgggcagatg aaaaaatagt taaaggaact
    22261 ttaagtgata tagctgtaaa agttaaagaa aacaacataa ataagactgc tttaataatg
    22321 gttgggagat ttttaggaga agagtataat aattcaaagt tatatgataa ggatttcaaa
    22381 catgaatata gagggtaata ttgctataat ctgtattaca gaaaatggaa aaaaattagc
    22441 tctaaagata aattctctag taaataactg tgttatatat caagtaaaaa ataaaaaaag
    22501 taatttagtt gttgaagaaa catgtgtgca tacagttcaa aagaagttaa gtgattttgt
    22561 aggagaaata tttagcaaat ttgattacat agtattcata atggctacag gtatagttgt
    22621 acgaagtata gcaccataca taataagtaa gtttagtgac cctgcaattt tggtaatgga
    22681 tgaaaaaggc aaaaacgtaa taagtttatt gagtggtcat attggagggg caaacagctt
    22741 gacacagtac ataagtagta ttattgatgc taatccagta ataacaacag ctactgatat
    22801 aaatcaaaaa gcttccttag atatgatagc aaaaaaacta aatgcacata ttgataattt
    22861 tagagaaagt gtaaaagaag taaattctat gctagtgaat aataaatgtg ttggattata
    22921 tgttgatgaa ggatatcaag ttgatactag gggatttaaa cttatagaaa gtaaggatga
    22981 gttaagagat agtttttcaa acgcatatat agaaaaatta gttgtagtaa gcaataaaat
    23041 aaattgtatt gaagatattg agaatttaaa cctagataat aaatttgaac attgctatag
    23101 tacccaaaaa ataataaagg taattccaag agatatagtg ataggaattg gttgtagaag
    23161 aaacacagat agtgaactga tgtataattc acttgaagag tttcttaata aacaaaatac
    23221 agatattaga gcaataaaca cagttggaag tatagaactg aaaaaagacg aaaaagcaat
    23281 aattgaatta tcaaaaatat tgaaggtgcc atttaaaaca ttttcagtag atgaaatatc
    23341 taaggttgat aatctttttg ataaatctga ttttgttaaa aaaaatgtgg gcgtgtattc
    23401 agtagcagaa cctgtagcat atcttttgag caaaggtaat ttgttagttg aaaaacataa
    23461 atataaagga ataacttttt cagtggggag aataaaaata tgatatacgt tgtaggaatt
    23521 ggaccaggaa gtaaagatac aatgacttta gaagcaataa aagcaataga agattctgag
    23581 gctattgttg gatataagac ttatataaaa ctaatagaag aatttataca aggtaaagaa
    23641 ataatccaaa atggtatgag gcaagaagtt gatagatgta aacaagcagt agaggaagca
    23701 aaaaaaggaa aaaaagtagc agttgtaagc agtggtgatg ctggaatata tgggatggca
    23761 ggtcttattt tagaattaat atctaaagaa gatgaagata taaaagtaaa ggtaattcca
    23821 ggtgttactg caagtattgg tgcagcagct atacttggag ctcctattat gcatgatttc
    23881 tgtcatataa gtttgagtga tttaatgact ccgtgggaag taattgaaaa aagattgaga
    23941 ttggccgctg aagccgattt tgtaatttgt ttgtataatc caagaagtaa gggaagaagt
    24001 gaacatctaa gcaaagcatt taaaataatg ggtgagttta aaggtggaga tacacctgtt
    24061 ggagtggtaa aagatgtagg tagagaaaaa gaagaaaagt ttgtatgtac ttttgaaaat
    24121 atggactttg aaaaagtcga tatgactaca atggttataa taggaaataa gtctacctat
    24181 attaatggtg aattgatgat aactccaaga ggttatacag tatgatttta attttaggag
    24241 gaacttcaga tagtttatct atatgtgata agataaatga actgaaaaat caaccatata
    24301 tcctttcagt tactacagat tatggaaggg aacttgcaca acaacatgca gagaatgtaa
    24361 ttttaggtaa gcttggaaaa gaagatatgc taaaatttat aaaagataat aatatagtaa
    24421 aaataataga tgccactcat ccttatgcag ttgaagtatc caaaactgct attacttgtg
    24481 caaaactatt gaatatagat tatataaggt ttgagagaaa atctttaatt gaagaaatag
    24541 attatgataa taaatttata gtagatacaa ttgaagaagc ctgtgaaata gcaaataaaa
    24601 tagggacaaa tatatttata ggaacaggaa gtaaaaattt gaacagattt atagaggaaa
    24661 taagtgataa aaatttagtt gttagagttc ttccaacgag tgaagtcata ttaagttgtg
    24721 aaaaattagg tttaagtgca gataatatag tagctatgaa aggtccattt agccagtata
    24781 taaatgaaga aacatataaa cattacaata tagatttagt cataacaaaa gaaagtggaa
    24841 tagctggtgg gttcttagag aaggtaaatg catgtaaaac tttcaatata ccagtaataa
    24901 ttataaaaag agaatcgatt aactacgaaa atgtatttaa tgacataaat aaaattaaag
    24961 acatacttgt gtaattttta ggaggagaat atatgaagaa agccttatta gtagtgagtt
    25021 ttggtacaag ctatcatgaa acgagagaaa agacaataga tatatgtgaa gataaaataa
    25081 aaaattcgtt aaaaagccat gattttttta gagcttatac atcaaatatg ataataaata
    25141 aaataaaaaa aagggatgga atagaaatag ataatccaat acaggcttta gataaaatat
    25201 atgaacaagg atatgatgaa gtaataatcc aaacacttca tattatatgt ggcgaagaat
    25261 ttaacaaatt aaaagaacaa gtagatggat attcttctaa attcaaaaag attgtattag
    25321 gaagaccttt gcttacacat attgaagatt atcaggaagc tgtagaggca attaagcatc
    25381 aaattcctca tatggaaagt aatgaagcag tagtatttat gggacatgga acacttcatg
    25441 aatcacattc agcgtatcca gcattggaat acatgcttag ggataatgga ataaatgctt
    25501 atgttggtac agttgaaggg tatccagaaa tagaacatgt aataagaaga ttaaaagaag
    25561 gaaatataaa aactgtaaat ttgatgccat ttatgttagt tgcaggagac catgctataa
    25621 atgatatggc aggagatgaa gaagattctt ggaaaacaat attagaagaa aatggatttg
    25681 acgtaagagt tcatttaaaa ggactaggag aaaattctta tatacaagat aaatttgttc
    25741 gtcatgctgt aaaatgtgca gagaatgcga agttctatgg tataggagca gggccaggag
    25801 atggttcttt acttacgata aaagcggtta atactttaaa gaaactggat attctataca
    25861 ctccagaatc aaaaaagggt ggagatagtc tagctttatc aatagttagt gaatatttac
    25921 ctgaatcagt ggaaataaag tctaggcatt tcccaatgag ttttgatggg aatgaaaaaa
    25981 gtttagcttg ggataatgta gcacaagaaa ttatatcaga tgttaatgat ggtaaaaatg
    26041 taggatttgt tacattagga gaccctatga tttatagtac atatgtatat ataatgaaaa
    26101 gaatattagg agaggtagaa gtcgaaacta taccaggaat ttcatcattt tccaatatag
    26161 catctaatca gaattttcca ttagtcatgg acaaagaagc tttagtggta attccttgta
    26221 ctatggaaga tgataagata gagtatgctt tgcaaaatta taattcaata gtattgatga
    26281 aagtatataa aaattttaaa gaaataataa aaaaattaga aaagtatgat ttaatagaac
    26341 atgctatttt agtaagtaat tcttcccaag aaagcgaaaa tgtgtttaca gatttaaaag
    26401 aagcgcacct tgaagataag atatcttatt tttctactat actagtaaat aaagataata
    26461 aaataaaata ggtgaaagca atatttaaag gagacttaat atgaatatag tggttggaac
    26521 taggggtagt aatctagcgc ttatacaaac agaatgggta ataaatgagt taaaaaagaa
    26581 gtatccagaa attagttttg agattaaaat cataaagaca aaaggagatt taattcaaaa
    26641 tgtttcactg gataaaatag gtgataaagg attgtttgtc aaagaaatag agcaacaatt
    26701 attagatgga aaaatagaca tagcagtaca tagtatgaaa gatatgcctt cttatttagc
    26761 agatggacta aaatttgctc atacgcctaa gagagaagac ccaagagatg ttctaatact
    26821 tagagaagga tataaaaatt tagatgattt gcctcatgga gcagtaatag gaacaggaag
    26881 taaaagaagg aagtttcaat tattgaaaca aagacctgat ttaaatatag tacaagttag
    26941 aggtaatgtg gaaactagga tacgaaaaat aaaagatgaa aacatgcatg gtattgtgtt
    27001 ggcagcatca ggaataatta gagctaattt acaagataaa ataagttctt atttacctgt
    27061 tgatgttgtt attccagcac ctgcccaagg agctttagct atagaaatta gaagcaatga
    27121 tagtacgata gagggaatag taaattcact gaaggatgag aatacagaaa tccaaatatt
    27181 ggctgaaaga ggttttttag atggtgtaaa tggaagttgt catattccaa tggcagctta
    27241 ttgtgaaata atccaagata aaatacatct tactggctta tatggagatt cagaaggaaa
    27301 aaaagtagta attaagtcta tagatggaga tatttcttct cctagagagt taggtttaaa
    27361 gttagctaaa cttgtattga aggagtatga gaattatgaa gggtaaggtt tacttagtag
    27421 gggcaggacc aggtgattat aaactcatga ctttaaaagg tttagagtgt ataagaaaat
    27481 cggatgtaat agtatatgat agattagcaa atagtagtta tttaagagaa gctaagcctg
    27541 attgtgaact tatatatgta ggtaaggcat caagtaatca tattttgcca caagaagata
    27601 taaatagaat tatagcagaa aaagctaaag aaggaaaaat tgtaactcgt cttaaaggag
    27661 gagaccctta tgtatttggc agagggggag aagaagcaga gactttagta gatgaaggta
    27721 tagaatttga agtagttcca ggtataactt ctgctatagg aggtttatgt tatgcgggta
    27781 ttcctataac acatagagac catgcttcgt catttcatgt aataacaggt catttgaagg
    27841 gtgatgatag tggagaatta aactggaatg ctcttgcaaa taacaaaggt actcttgtgt
    27901 ttttgatggg aatttcaaac ctagagaaaa taagtgaaaa cttaatgaaa gaaggaaaag
    27961 ataaggatac ccctgttgct cttataagtt gggcaactag atataatcaa agagttgtta
    28021 catctacact tgaaaatgtt tatgaaactg ctattaaaga agaagtaaaa ccgccaactc
    28081 ttatagtagt tgggagtgtt gtaggactta gagaaaagtt gaacttcttt gaaagtaagc
    28141 ctttatttgg aaaaagtatt gctgtaacta ggtctagaaa tcaaaatagt gtattggtag
    28201 aaaaaataat ggatttaggt ggaaatccta tagaaatacc tactattaag gtagaaaaaa
    28261 tacaaaataa tattaactta gaaaatgaaa taaaaaatat aaataagtat aattatctaa
    28321 tactaactag taaaaatgcc gtagaaatct tctttgaaaa gatatatgaa atgaattttg
    28381 atttaaggat attatctaat ttaaaggtat gtgctatagg ttctgctaca tcaaatgagt
    28441 tgaaaaaaag aggaattata gcggatatag taccaaaaaa atttgtagca gagtcactgt
    28501 atgaagagtt agtgcctatt ttaaatgatg acgataatat acttatacct agagcagaaa
    28561 atgctagaga ttatctggtt gacaaactta aggctatttg tgaagtaaca gaagtacata
    28621 tatatagaac agtaatagat gaggagaaaa aaggtgagat attagatatt ttaaattcta
    28681 atgacataga ttatataaca tttactagtt cctcaacagt aaataatctt gttgaaatta
    28741 taggaaaaga aaatattaaa atattagaaa aaataaaaac actatctata ggtcctataa
    28801 ctacagagac aataaatagt ttgggaataa aattgtacaa agaatctgct acatctacta
    28861 tagattcgtt agtagattta attataaaaa attaattttg gaggcttgaa tatgttaaga
    28921 agaccaagaa gactaagagc aagtaaagca atcagaaatt tggtaagaga aactaaggtg
    28981 aatgtagaag acttaatata tccactgttt gtagtagagg gggaaaatat aaaagaagaa
    29041 attaaatctt taccagatgt ctatcattta tcaatagaca tgctagaaga cgaaataaaa
    29101 gaaataagtg agttgggaat tgaacatata atgttatttg gtgttccaga tgaaaaagat
    29161 gagtgtgctt cacaagcttt taatgataat ggaatagttc aaaaggcaat tagaaaggta
    29221 aaagaaataa attcagatat aaatgtaata acagatgtct gtatgtgcca atatacaagt
    29281 catggacatt gtgggatttt aactgatact ggttatgttg ataatgataa atcattggag
    29341 tatttggcta aaatatctgt aagccatgct aaagcaggag ctgatatggt tgctccatct
    29401 gatatgatgg atggaagaat acaagcaata agagaagctt tagatgaaaa tggattagaa
    29461 aatgttggaa tcatggctta tagtgttaag tatgcttcaa attattatgg accttttaga
    29521 gaggcagctc attcagcacc atcttttgga gatagaaaaa catatcaaat ggacccagca
    29581 aatagcaatg aagctataat agagactgaa cttgatatat tggaaggtgc agatatactt
    29641 atggttaaac ctgcattatc atatttagat attataagaa gagttaaaga taattttgac
    29701 ttacctctag cagcttataa tgtaagtgga gaatactcta tgcttaagtt tgctgtgaag
    29761 gaaggtttat taaatgaaga tgtaattctt gaatcaatta catctataaa aagagcagga
    29821 gcagatataa taataactta ttttgctaaa gacattgcta aactgttgaa aaaataaatt
    29881 ctagtagtat aaagaatatc aaaaagtata ggaattgtaa ttaactatta tacagtagtt
    29941 ttgtttagac atttattgaa gaataataga aactaatttg caatttctat actttattta
    30001 tgtaactaaa taaaatttgg aggtggaaga tgctatatcc tattaattta aaattagatg
    30061 agttagatgt agttataatt ggtggtggag aagttgcata taggaaatgt aaaaattttt
    30121 tagagtttaa caaaaatgtt actatagttt ctaaacaaat tttaaataaa ttttatgatt
    30181 taaaaggaaa tataaaaata ataaaagatg attataaaga aatatatata aaagatgctt
    30241 ctgtaataat tgctgccaca aataatagag agttaaatat ggaaatagga ttatattgta
    30301 gagcaaaaaa taagctagtg aatgtagttg ataatataga aatatcgaac tttacggttc
    30361 catcatatat aaaaagagga gatttactta taagtgtgtc tactgggggc aagagtcctt
    30421 cattatcatc aaagataaaa aaagaaattg aagagagata tactgaagat tatgaggagt
    30481 atttaaatgt attaggagat ataagaaaaa aggttataaa aaaatacgaa gataaaagta
    30541 aaagaaaaga cgtgcttaat gtgttggtaa cacttgacct agaagaactt aagaagtttg
    30601 atatataaaa aataaaataa aaaatgttaa aaaggtgttg acggattatt tttaag
//
LOCUS       DAEPXW010000045        29937 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.046, whole genome shotgun sequence.
ACCESSION   DAEPXW010000045 DAEPXW010000000
VERSION     DAEPXW010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29937
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.046"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            185..1813
                     /gene="aspD"
                     /locus_tag="KRM55_002017"
     CDS             185..1813
                     /gene="aspD"
                     /locus_tag="KRM55_002017"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBH1594261.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
     gene            1934..2929
                     /locus_tag="KRM55_002018"
     CDS             1934..2929
                     /locus_tag="KRM55_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBH1594262.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(3118..3501)
                     /locus_tag="KRM55_002019"
                     /pseudo
     CDS             complement(3118..3501)
                     /locus_tag="KRM55_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      3727..3824
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     repeat_region   3966..4525
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3966..3994
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(4811..4969)
                     /locus_tag="KRM55_002020"
     CDS             complement(4811..4969)
                     /locus_tag="KRM55_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594263.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     gene            complement(5328..6698)
                     /locus_tag="KRM55_002021"
     CDS             complement(5328..6698)
                     /locus_tag="KRM55_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HBH1594264.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            6981..7079
                     /locus_tag="KRM55_002022"
                     /pseudo
     CDS             6981..7079
                     /locus_tag="KRM55_002022"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            7098..7519
                     /locus_tag="KRM55_002023"
                     /pseudo
     CDS             7098..7519
                     /locus_tag="KRM55_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7750..8022
                     /locus_tag="KRM55_002024"
     CDS             7750..8022
                     /locus_tag="KRM55_002024"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1594265.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(8340..9008)
                     /locus_tag="KRM55_002025"
     CDS             complement(8340..9008)
                     /locus_tag="KRM55_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH1594266.1"
                     /translation="METVTNNRSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(9862..12282)
                     /locus_tag="KRM55_002026"
     CDS             complement(9862..12282)
                     /locus_tag="KRM55_002026"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBH1594267.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            complement(12636..12986)
                     /gene="rsfS"
                     /locus_tag="KRM55_002027"
     CDS             complement(12636..12986)
                     /gene="rsfS"
                     /locus_tag="KRM55_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBH1594268.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            complement(13103..13675)
                     /gene="yqeK"
                     /locus_tag="KRM55_002028"
     CDS             complement(13103..13675)
                     /gene="yqeK"
                     /locus_tag="KRM55_002028"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBH1594269.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            complement(13676..14365)
                     /locus_tag="KRM55_002029"
     CDS             complement(13676..14365)
                     /locus_tag="KRM55_002029"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBH1594270.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            14641..15279
                     /gene="recX"
                     /locus_tag="KRM55_002030"
     CDS             14641..15279
                     /gene="recX"
                     /locus_tag="KRM55_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBH1594271.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            15432..17435
                     /locus_tag="KRM55_002031"
     CDS             15432..17435
                     /locus_tag="KRM55_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBH1594272.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     NFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLSFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            17609..18250
                     /locus_tag="KRM55_002032"
     CDS             17609..18250
                     /locus_tag="KRM55_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1594273.1"
                     /translation="MGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDGLSR
                     GAIYHHFKSKDEIIKAITSRLYSDGFYGYDVKNDEGKTALEKLQYRLLHAYEQHNKQD
                     IFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMEVKNPEIAAQMFGFL
                     LNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            18343..19026
                     /locus_tag="KRM55_002033"
     CDS             18343..19026
                     /locus_tag="KRM55_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594274.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(19203..19514)
                     /locus_tag="KRM55_002034"
     CDS             complement(19203..19514)
                     /locus_tag="KRM55_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBH1594275.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(19592..20410)
                     /locus_tag="KRM55_002035"
     CDS             complement(19592..20410)
                     /locus_tag="KRM55_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1594276.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDFMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGVSFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSKLFAKKLEESLSPTQSVEKVVLCLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            complement(20510..21034)
                     /locus_tag="KRM55_002036"
     CDS             complement(20510..21034)
                     /locus_tag="KRM55_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1594277.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            complement(21053..22195)
                     /locus_tag="KRM55_002037"
     CDS             complement(21053..22195)
                     /locus_tag="KRM55_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH1594278.1"
                     /translation="MNKKINYAPGPTETRENVRLVRAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKVPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            complement(22475..24862)
                     /locus_tag="KRM55_002038"
     CDS             complement(22475..24862)
                     /locus_tag="KRM55_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1594279.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKSDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            complement(24855..25538)
                     /locus_tag="KRM55_002039"
     CDS             complement(24855..25538)
                     /locus_tag="KRM55_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594280.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VLKVGDKND"
     gene            complement(25655..26965)
                     /locus_tag="KRM55_002040"
     CDS             complement(25655..26965)
                     /locus_tag="KRM55_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1594281.1"
                     /translation="MLKNMNLKDVLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKSEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            complement(26959..27666)
                     /locus_tag="KRM55_002041"
     CDS             complement(26959..27666)
                     /locus_tag="KRM55_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594282.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            complement(27971..29812)
                     /locus_tag="KRM55_002042"
     CDS             complement(27971..29812)
                     /locus_tag="KRM55_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HBH1594283.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGEHTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFNNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPILKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSSRESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
BASE COUNT        10150 a         4801 c         3575 g        11411 t
ORIGIN      
        1 atcatttttt attaaaaggt attttttatt ttaacatata tttaataagg ctaaatagag
       61 ttattatttt aatttcatac tttacttttt ctataaacct attataatta aagtataatc
      121 atttttgcaa cttgtttatt ttattataaa aatgtgaaac ttattacata aggaggaatt
      181 taacatgaaa aatcatactt ataaagaaat caaaaacata tatggaaaaa taagcccttt
      241 tgaatttaag gacaaattaa tagatattgc aaaatacact gcaaaagaaa ataacagaga
      301 attacttgat gcaggtcgtg gaaatccaaa ctggacttgt tcaactgcta gagaagcctt
      361 ttttactttt ggtcatttcg ctattactga aactcgttcc aattgggatt taggtcattt
      421 ggctggaatg cctcaaaaaa agggtattaa agaaagattt tttaaattta taaatgaaaa
      481 tatagatatg cctggagcat atttagctag agatattata aactttggta taaatgaact
      541 tggatttgat ggtgatgaat ttgttcatga actagctgat ggaattattg gtgataacta
      601 tccacttcca gatagaatgt tacctcatat ggaaaaaata gtacacgatt acctagttca
      661 agaaatgaaa tatgatatat caggtaaata tggtgatgta gaaatttttg ctgttgaagg
      721 tgctacagct gctatgtgct atatatttga ttcattaatg gcaaatgaac ttctaaaaaa
      781 aggagatacc atagccttaa tgactccaat atttacacct tatcttgaaa tacctaacct
      841 tcctcgttac gactttaaag tggtaaatat aaatgctaat gaagttgatg aaaaaggtgc
      901 tcatacatgg caatatacaa aaaaagaatt agagaaactt cgtgacaaat ctattaaagc
      961 tttattcgtt gttaatccta ataatcctgc ttctatagct atggatgaaa catcttgtaa
     1021 taatctaata gatgtaattg aaaattataa taaagattta atgataatat cagatgatgt
     1081 atatggaact tttgtagaag atttttcatc cttaatgtca aaactacctt acaacactgt
     1141 tggagtatat tcttattcaa aatattttgg agttacagga tggagacttg gtacatttgc
     1201 ccttcataag aaaaatgttt ttgataagaa aataaatgat ttaactggag aattaaaaaa
     1261 atcagtagat aagcgttaca gtgatatgag tcttaaccct tctagtcttt cctttatgga
     1321 aagagttgtt gctgatagca gacttgttgc tctcaaccat actgctggtc tttctactcc
     1381 acagcaagta caaatggcgt ttttctctgc ttttgcattg attgacaaag tagatgccta
     1441 caaaaaactc aatatgagta tctgccatag acgtcaaaaa ctattatttg aagctttaga
     1501 gcttccaatt aatgaaaaca aaaacaatgc tgcatattac actcaatttg atattgaaga
     1561 atgggctaaa ttaaactacg gagaagactt atttaaattt ataagtaaaa ctgcatctcc
     1621 agtagatgtt ctttataaat tagctaatga ctattcagta gttttactta gtggaaatgg
     1681 attctatggc cctgaatggt caattagaat atctctagca aatctatatg atgaagctta
     1741 tactaagata ggaaaagcca taagagagat attaaatggt tatatcgttg aatggcaaaa
     1801 aattaagaaa taattatatt acactgaaat atctaaatta tatgaataaa agagtttatg
     1861 tagaccttaa ctactttttt tgatataatc ctatcggaat tataaatttt atttatgaaa
     1921 ggcagagaat agtatgagta ttaagaaaaa agttgccata gtttttactg gtggaactat
     1981 atctatgaca gtagatgata aagtcggagc agctatacca actttatcag gtgaacaaat
     2041 actatcaatg gttaccaaca ttgataaagt tgcagatgtt gaagttttta attttgatga
     2101 aattccagga cctcacataa caccttatag aatgatggaa ttgaaaaact atgtaaatga
     2161 tttattagca agaaaagata ttacaggtgt tgtaataaca catggtacag atagtttaga
     2221 ggaaacagct tatttcctag accttacaat tgacaacatc aaacctgtaa tagtcacagg
     2281 tgctatgaga agtagttctg aacttggata tgatggttca agtaatttat ctgcatcagt
     2341 ttgtactgca gtatccaaag atgctatggg aaaaggagtc cttgtagttt taaacaatga
     2401 agtattatta gcttctgaag ctactaaaac aaatactctt tctctaaata catttaaatc
     2461 tctaactagt ggtccattgg gaataattga ctgcaacgaa cttgtcctta caagagatat
     2521 tgtaaataga acaattatag atactgataa ggtagaatct aaagttgcct tatttaaagc
     2581 atatgtagga gaaaatgctg actttataag atttgctgtt gatagtggtt ataaaggtat
     2641 agttattgag gcaatgggca gaggtaatat tcctcctcaa atgctttctg gagttgaata
     2701 tgctagagaa aaaggacttc ctgtagttat agtttctaga tgtcattcag gtagagtatt
     2761 cgatagttat ggttactttg gttctggtag agatttaaaa aatcttggtt gtatatttgg
     2821 tggggactta ccaggtcaaa aagctagaat aaaacttatc ttagcacttg gaaaaactga
     2881 taaccttgat gaaatcaaag acttctttga aaaaggaatc tattgttaat tctaataact
     2941 tctatttaat tatttattga tatttcaaca tttttaaatc aaaatctaat acttatgtca
     3001 gttaaatgtc agcaaaatat tttatccaca atttttacac aaattttcca caacttatcc
     3061 ccaatattat ccacaagaaa aaaggtagca cttatattag tagctacctt ttatttatta
     3121 atcttcatct ttccagcttt ttatccaatt tcctatttct attatttttt cttcagttat
     3181 ttcttctcca tcatgtaatt ttgaaattag ttctgataat ggattgttat gtagacctcc
     3241 aaaaattctt tttccctcta ttttgagata ttctttctct tttattaata ctctatagtg
     3301 tacatgtttc ccaattctct gcgatatgaa aaaacctttt ttagttaatc tagctaaaag
     3361 tgtaattgta gttgtatgct tccaagcata tgttttttct atttaatctg caacatcttt
     3421 tgatattaca gttttataac cagtattcca tatgtatttc ataattttta attctgcatc
     3481 tggtaatttt ttattcaaca taatatattc cttctttcaa tttatgtcac ttcctcaaac
     3541 ttatctagct taaattaata ataggagctt tttatcacaa aaactacagg taaatttttc
     3601 tatatattct acgtatttag tctgttttta agtgtgaaat tacgttcata cctataaatt
     3661 tattcaattt tcaaacaatc ttgttgaata ataactaatt ctattgtatt atttagttat
     3721 agaataaaac taaatcggca aaactagaga aatatagtga cgcaaagcta tagggactaa
     3781 gacttatata aatatcttat gagttatgtc agccagttgc caaagagata ttgttctttt
     3841 tgtttttatg aaagtttttt aaggggataa taatttatat gtttagagat aaaatggata
     3901 aatgtacaca tatattgact gcttatatta gcagttcgta tgattattgt aattttttgg
     3961 atacaattta cattccatat agttaatata aaactcaatt aaattatgac cttggtttag
     4021 atagttcatt atttacattc catatagtta atataaaact tctttatact tgcgctatta
     4081 tgtttgtggc ttgtaaattt acattccata tagttaatat aaaactgacc ctaaaaagat
     4141 agatttagca atagattcat gcttatttac attccatata gttaatataa aacaagattt
     4201 agattggttt gttagcatac attttaatgc atttacattc catatagtta atataaaacg
     4261 gaagtgggca agtaatgata tttacagata aaaggaattt acattccata tagttaatat
     4321 aaaacgttac aaatgttata aattttatta tttctgctct tgcatttaca ttccatatag
     4381 ttaatataaa acttaataga aactgtttca gcaataatag catctcgacc atttacattc
     4441 catatagtta atataaaacg agttttagtt gataatgtag atgaattatt taattcattt
     4501 acattccata tagttaatat aaaaccccaa aataaattga gtatttccaa tgcctacaca
     4561 tatacaaatc tctcaaattt gcagtgaacc atgagtagtg caattgataa cacttatcac
     4621 aagtcctcaa tgccttatat ttcaactgtt aagccttaat ttcttcaaaa aatcgaacac
     4681 tgcaaaattt ctatgacttt attatatcat aaaaatatta tttttgaata tctgtaccaa
     4741 tttgtgatat aataaaagca agaagaacta caatctattt tgctgtagag tggagttcat
     4801 aatttagaaa ttacttagtt ttatggaatc tgatttttaa atcaaattcc caaccactct
     4861 tagttgccgc tttgagtggt tttttacgct ttctaaatag tttgctagct atataaacta
     4921 ttaagctagc agatagactt gctagtatgc cttgtaaaaa attatccatg tatattcacc
     4981 tcccttctta gcgtcgggag gataattttt tgatacatga actccactct ataaattgta
     5041 gattacatct tcttgctaaa aatattataa catataattc ttacatattt tacctattta
     5101 ttacttttta cattataata atattctttt aatcaaaaaa acacctacta ttaaagtaaa
     5161 tgtttttaag tatttttaat tttaaaatcc atatagttca tatgaaacta aatataataa
     5221 ctcaacatat gagcaatatc gagacattta cataccacat agttaatata aaacgaaaat
     5281 aaaaaaatta aacttataaa acccttatta atttacatac ccactagtta tttatattca
     5341 aaaaaatctt ctccatctgg gttataaaat aatattctac ttgccaatcc ttgttcatat
     5401 ttataatttt ctttatcacc tacataagaa aatgttaatg tcatgcttct tgatggatct
     5461 aatgaaatta tatctaaata aatagtacat ttttctcctg gctttaatac accgaaacta
     5521 ttaaaatcca tttttatttt agcatattgc cccatatata atgttgaatt agcttctcca
     5581 taaactttta attttgttac atctaaattt tgtgtacttg tattttctat atttatagga
     5641 actgttgggt ctttatattt ttcagtataa tattcaaggt tatcatcata acattcaaga
     5701 taacttcctt tatcttgcca aattatgtgc tttgaatcaa aatcaatctt taatccacat
     5761 attatatttt tatttgaaga cggaagacta atattattga tggtattttc acactctagc
     5821 ataattttat cacttagatt tcctatccca gtcacttttg cagcattttt aagtatatct
     5881 ttattacttc caatatcaac tagtacaata ggattatttt tagccattgg tgaagcaact
     5941 aaagcataaa ctaaatcagt accactagct atataaaatt cttttgcgcc attatagaac
     6001 ttatttacta tttttttatt agtatcatat ctatctactc cacctaatct agttgaatta
     6061 gtatcattaa ctagtttgtc actcattgat gaagtaccac ctattacata actttctaca
     6121 ccagttgtat taaatggaac actttttcca tcagttaata ctatagctgc tttatctcta
     6181 actgctacag gtgcagcact cattgcatca ggctctcctt taaaagcatt agtcaatata
     6241 actttattta ctttgttaat tgagtttatt tcttttgcaa cattatagct tgtcttaatt
     6301 ctatcactac cttgaagtct tttagcctct attcctttat cttttagaag agtttctgtt
     6361 gctttatcaa tagaactttc tccacctatt atgtatacct ttttagcttt ctctactctt
     6421 ttaagagttg cattaggtat gttatttttc ttagttaaaa aaattggtgc atttgttgct
     6481 cctgcaagtc cactcgcact taatccatca gccattgtgc tgtctgcatt aattaatata
     6541 gctgtagtat aattttgttc atcagctata agagcagccg tttcatattt atcttttcct
     6601 tgaatagtat aaattgtatc aagtgcatta gctgatatag gaccagcagc aaacattgac
     6661 acggctaacc ctagtgataa taatttcttt aatttcacaa tatctccccc ttttatatat
     6721 gaaatactat atatcttaca taattctaca ttaaattttc ttttcctcct ttaacgatat
     6781 ttatcttcct gttaatttaa gtgtatacaa atacgtgtta taatgtaact gtaaagaatt
     6841 aaaaagataa tgacataatt agagcagtcc aactgttctt ttataaaact aacttataaa
     6901 gggagcgtac atatatgaat atcaaatcag cttttataag aaaaagatgg gaaaaattct
     6961 atgtatatgt ggaataagaa actggcaaaa agaaacaaaa aagttatgga agctataaaa
     7021 agaaaaagga tgctgaaaaa catttaattg aaataaagtc tactataaat aataataagt
     7081 ttgttgctcc aaaaggtatg acatttgtag aaagatgtta taaatatata gacatgaata
     7141 aaaataattg gtctccatat actgttacaa atacaaaatc ttgggttaaa aattacatag
     7201 aacctttttt aagaatctaa aactcacaga agtaaatcct agttcagtac aagcttttgt
     7261 aaattataac tttaataatt ctacctttac tagtgctaaa gtaaggtata gctttctaag
     7321 ttctgtaata agggaagcgt atagattaag agaaatacaa gaaaattcat gtgattttat
     7381 aaaacttcct tctaaagaaa aatattctac aaatgaaata tacaatagag aagaagtatt
     7441 attgctaata gaaaagttac ttggtaataa tatagaaata cctattcttt taatgttact
     7501 tctaggttta agaatgtgag aagctattgg gcttaggtgg tcagatgttg acttagataa
     7561 caatctgata aatgttaatc aaattcttgt ctattctaat ggcaaaatat cttttaaaga
     7621 gccaaaaaca ccaaaatcaa aaagagcttt atcagctcca aaagaattaa ttgaaaaatt
     7681 gaaaattgaa aaactaagac aaagcaaatt aaaattgtaa ggtatcctgg aaaacagaaa
     7741 taacttagtt tgtctaaaca ccaatttaaa tccgtttcta ccttcttcac taagaaaaac
     7801 gtttcacaat tttacaaaaa aaataattta aaaaagatta gaatacatga tttaagatat
     7861 acaagtgcca ctctgctgct tttaggggga actaatatga aagttgtttc tgaaagattg
     7921 ggtcatacag atataaaaat aactatgaat agatattctc atgtacttaa agaaatggac
     7981 aaagaagctt ccgacaatct aagcgaactt ctatttaaat agtaaaaact gactgtcagt
     8041 taaatgtcag ttaaacctaa aaaaataggt tttgtcagtt gattgtcagt caattatttt
     8101 ataatagttt cacttaaaaa cgtctatatc tacacatttt actatttgtt tatgcttatt
     8161 aatatctatc tgttattatt aattctaata gcttctattt aattatttag ttcagtttac
     8221 aggaaactac acacaaacca taaaatagga tgttgacaat ataacagata gtatgctcct
     8281 gtaaaaggta acatagtatc tgttatattg tctggattcc caaattagct atttggaact
     8341 taactaaaaa atcctaatat aagggcaact attataatgg caatcggaat acatactgtg
     8401 taatcctgtt ccatagagtc atcatctgaa tgtagtttta caattcgcaa tttagcaatc
     8461 agtttgaagc aaaaatagcc tattattgtt ccaattacgt tcgtgagtaa gtcgtctata
     8521 tcggttgctc tgtgtaacgt aaaaagctga atagtttcga taaaaagaga taatccaaaa
     8581 ccaatcaaga atgtatttct caaacgttca aaggttttgc ttataagcgg acataaaaaa
     8641 cctaatggga caaaaagtaa aatattcaaa ataaaactca aactaaatcc atcactaaaa
     8701 ggaataagat ttatgtttgg attaaagaac gtttccccta actgtgacag tcttatatat
     8761 tcactgaatg tagggatacc aacaatatgc gatagtgtta aacataagta gtaatacatt
     8821 gccagtgata aaatagatgt ttttaccttt ggaatatcac tatttttctt gaatattaca
     8881 actaagaaaa taccaatcaa gataattccc aacaagaaaa taggattaat taacaataaa
     8941 tctttgatag cttcaaacag actgagttga atttctacac ctgatcgatt atttgttaca
     9001 gtctccattt gtacatacct cctcataaca tttcaattat ttctaaaaca caaaatagaa
     9061 gataaatctt aaaatcatcc tatcaaaatt tttaaatttg cctttatcag tttataccac
     9121 cagttaattc ctgtcttact tctgtatggt attcttggga ttctttcatc aaattagaca
     9181 aaaaaatggt taccatatca ataaactggt tacgctccat atctcccgaa gcaaccatcc
     9241 cctgagaata aatccgtatc aggaatctcc acatctactg cacctatcac aagttatttg
     9301 ataacatcct cagacaatcc caacttggat atatcgacaa cacccattag aataccactg
     9361 ctgaccatac ttgttttcct gctgataatt tcaatcaact gggaagttta aacgctatct
     9421 tttttacaag ttccttttta gaaacatggt agctattata tgaatctgaa tttcgttgtc
     9481 tgggtgtttc atataaagca tagatacgca ccttttttgc ctgttttcat tatatagaaa
     9541 aaaatttcaa aatacaataa ttatattttt ttcgtttaag cttagagcag ttccttgatg
     9601 aacaacactt tggaaactga atgatttaca taccacttaa tacattaact cgatttaaca
     9661 ttaattataa taatatttaa aacaacaact agggtatata agaatgaact ttttagttct
     9721 ttaatcattt ttttgtataa aatcaaatct atttttataa tttcaacaat tttataattt
     9781 caacaatgaa aaaaggctta tctctatttt gagacagcct catttatttt ataaatttat
     9841 atttttgttc atatttttga gttatttaac aactatattt actagttttt taggtacagc
     9901 tacaacttta actatagttt taccttcaac taatcctttt attttttcat cttctaaagc
     9961 taccttttcc atctcatctt tagatatatt tgagttaaca gttaattttc ctctaacttt
    10021 tccattaact tgtacaacaa cttctatttc atcttttact aaagcttttt cgtcatattt
    10081 aggccagtct atatcaaata cacttccttc tttacctatc atagtccata gttcttcacc
    10141 taaatgaggg gcaaatggtg caattatagt tactatagtt tgtacacctt cttttataac
    10201 tgcttcgttt atattatcta actctttata tttatacata tcatttatta attccataag
    10261 agctgatata gcagtattaa atccgaattt ttcacttaaa tcagcagtaa cttttttaag
    10321 tgtagagtgt atagtatatc tcatatcctt atcttgggaa tttaattctc caaactctac
    10381 atccttttta accacatctg ctaactcgtc aaccaatcta taaaccctat ttaagaatct
    10441 aaagcatcca tcaacacctt gctctgacca gtctaaatct ctttctggtg gtgctgcaaa
    10501 taatacgaaa agtcttgcag tatctgctcc atactcatct attatatcca taggagatac
    10561 tgtattccct ttagacttac tcattttaga accatccata agtaccattc cttgagtaag
    10621 taagttttta aatggctcat tgaagtctac cattcccata ctcttaaatg cctttacaaa
    10681 ccatcttgca taaagcaaat gcattatagc atgttctact ccacctatat attggtctac
    10741 tggatgccat ctattaacta attccttact aaatggttca ttttcattat tgctatccac
    10801 atatcttaag aaataccaag aagaatcaac gaatgtatcc atagtatcaa cttcccttct
    10861 agctggtttt ccacagtgag gacaagttgt tgacataaat tgctttgaag tcgtaagtgg
    10921 agattctcct tttccagtaa attcaacatc tgttggtaaa agaactggta aatcttcctt
    10981 tttaactgga actattccac attcatcaca ataaaccaca ggtataggac aaccccagta
    11041 tctttgtctt gaaactaacc agtctctaag tctataatta attgttctct ttcctctacc
    11101 ttctttttct aacttatcga ttattccttc aaatccttct gaagcatcta atccattaaa
    11161 ttcttctgaa tttatcattt tgttatcttc tgttattaca tcaattatgt ctaaattata
    11221 tttttcagca aaatctctat ctctttcatc atgtgctgga actgccatta tagcacccgt
    11281 tccatactca actaatacat agttagctat ccatagagga actttcttgc catttaaagg
    11341 atttataaca tatctaccta taaacattcc ttctttttct acatcagctg ctgttctttc
    11401 tatttctgtc atagtatgca ttttttgaac aaaagcttca acatctgctt catattcagt
    11461 ccctgcaacc aattctttaa ctaattcatg ctctggagca agtaccatat aagtaactcc
    11521 ataagttgtg tctggtctag ttgtaaatac tgtcatagat ttatcagttc catctatatc
    11581 aaaaactaaa tctgctcctg tacttttacc tatccaattt ttttgcattg ttttaacttt
    11641 ttctggccat ccatctaatg tatctaagtc attaagtaat tcttctgcaa attcagtagt
    11701 cttaaaatac cattgttcta aatctttctt taatactgtt gctttacatc tctcacatgc
    11761 tccttgaaca acttgctcat ttgcaagaac agtctcacaa gaaggacacc agttaacata
    11821 tgattttttc ttatatgcaa gcccatgctc taaaaacttc aaaaatattt cttgtgtaaa
    11881 tctatagtat tctggagttg aagttgcaac ttctttatcc caatcataac taatccctaa
    11941 taaatttaat tgctctttca tttcttctat attttccatt gtccatttat gcggatgtat
    12001 tccatgtttt atagctgcat tttcagctgg taatccaaaa gaatcccatc ccattggatg
    12061 aagtacatta tatccttcca tttttttgaa tcttgcgaca acatcaccta tagaataatt
    12121 tctaacatgt cccatgtgta tttttccaga tggataaggg aacatttcta atgtgtaata
    12181 attaggtttt tcagtttgtg cagtatccat tttatactga ttattatctt tccagatttt
    12241 ttgccatttc gattctactt ctttaaaatt atatacgctc atattttgcc tcctattttt
    12301 aattgtgtat aactacctta tttagtatta tttacttata atttccaaat aattctttga
    12361 aaataaaaaa tcctcgtcac taaacttacg tttagggacg aggataaatc ttcgcggtac
    12421 caccctaatt agcctactac atatatagac tctcttagat agcttttaat ccagccatgg
    12481 agaatagatt ttaatctagt aagttcaaag ttatataata ttagttctca ccttccacta
    12541 actctctgaa aaaatataat cttttactgc tctagtctat tcaatttaat ataatttttg
    12601 aaattttcta attataataa catatattat catgtttatg ctaatgtgtc aatatctata
    12661 taaggtgcat ctttccataa tttttctaaa ttataaaacc ctctattttc ctcattaaat
    12721 acatgaacca ttatgtctcc ataatcaagg agtacccaag tttgagttcc ttgtccttct
    12781 ttacctcttg gctctaatcc tagttttgct aattcatctt ccacattgtc agcaatagct
    12841 tttacctgtc tctgagaaga tgctgtagta ataataaaat aatcacacaa actagaaact
    12901 tttcctatat ttattataac tgtatcttga cctagtttat cttctatggc atcatatgct
    12961 atttttgtca tttgttccac tgtcatataa aaattcctca ctttcctaat taaaatacac
    13021 ttagttattg taacatatta atacgatttt gtaacatagt caaatttaaa tttattaata
    13081 tgtttgcctt tatatagctt ttttataata acttttcttt aattagatag tttcttgcca
    13141 taactgttct tggatgtatc tcttcttttt tattgatgac aaacattaaa gtattattaa
    13201 aagaagttaa aagtgcttca tcaagcttcc ctccatatgc taattctctt aatgtatcta
    13261 caactgggaa ttttcttcct tcttcaatta aatcagctat gtaaattatt ttttctaaaa
    13321 gagacatgtc ctctctccct gttgtatgat atttgattgc atttataata tcttcatctt
    13381 ctacttcaaa ttcatactcg catatgtacg ccccaattac actatgagac aaggaacgat
    13441 ttccatcctc tattgggtct aaatatattt catacttatt tacataatcc tctatttcct
    13501 tgtcacttaa atactttgca caatcatgaa tcattcctgc taagtaagct ttttctttgt
    13561 cacatccata aatctcacat aatttttcag cacattttgc aacatttttt gaatggctaa
    13621 gcctccccac tggtagcatt tgatttagtc tttggttaat attttctaag ttcatttaat
    13681 catctccata ttgatatagt ttattttcat ataaataatt ttctacattt tcgggtacta
    13741 agtaacgtat tgacttgcct tcatttagct gttcccttat atatgtggac gatatatcca
    13801 gtgatggaac ataaactgtt ataatgtcag cattatactt cttagttagt ttttctatag
    13861 tctcttgtga ccttaacaaa ctaattcctg gtctagttgc ggctataaaa gtagctaact
    13921 caaagttttt ctttacatct ttccactctt caacactaca aattgcatct gcacctgtta
    13981 taaaataaat gtctgcattt ttgtattttt tctttaaata ttttaatgta tctattgtat
    14041 aagtcctttt ctttctttcg atttctactt ttgaaactaa aaaatcttcg ttgctttcag
    14101 ttgctagaag tgtcatatta tatctatcat acttatctgt agtgatacat aatttatgtg
    14161 gtggatttcc tgatggtata aagattattt tgtcaatgtc atacttgtct ctaataaatt
    14221 ctgctgttgc taaatgagca tagtgtatag ggtcaaaagt acctcccaat atacctattt
    14281 tgattttgcc tttatggcga ttaaatttct ctagtttttc agtatttttc aactctgcca
    14341 tcttaactag attttcactt ctcatatttt gtctcctttt aatgttataa tactattgta
    14401 ccattatttt ttatttctta aagcttataa tttgtttttt tgggtatata attatattta
    14461 tatgctaaaa aacactttaa aaaataatta tttaacatga ttctgcttta ctttttaata
    14521 aaaataactt tttactattt tgtcttaatt ttgataaaat ataacataca aatataagtt
    14581 ttttgttaaa ttttattagt tgcttttgtt aatataatta catataaaaa aggaggactt
    14641 atgggtataa ttacaaaaat agaacaacaa aaaagaaatg atgatagagt taatatttat
    14701 gtagatgata aattttttat tgctatattt aaagaacttg tttatacatt taatttaaaa
    14761 aaagggaatg aaataaatga agaagaatta aaacctattt tagatgatga aatgtatata
    14821 aaagctaaaa ataaagcatt aaatatttta tctcatgctg accaatctga aaaaaaatta
    14881 aaagaaaaac tatcatcaga atttgatgaa aatataattg agagggtcat agattttctt
    14941 aaaagttata atctcgtaaa tgacagtgta ttagctcaaa aaattgttaa cacaaatgtt
    15001 aacctaaata aatgtggcaa aaacagaatt aagcagaatt tatataataa aggtatcaat
    15061 agaagtacaa tcaatgaagc agtatctgaa ttagacaagg acactgaatt tgaaaatgct
    15121 atgtatctag caaaaaaaag gtatgaaaga gtaaagaaag aagataaaaa gaaaatatat
    15181 caaaaaattt ctcaacatct ttcctataaa ggctttgatt atgatattat taaaagagtt
    15241 ttaaacaaac ttttaaattt tgatgaatac gatatataag tataaatact agggaggtaa
    15301 attatgaaat taatcattgg tggcttaagc tttttattag gattatataa tatatatcaa
    15361 ttatacagag aagatagtat gagataaata ttatttttta gatgtaatat ttattatgga
    15421 ggagaaatac aatgaaaagt caaaaaagat ttaaaatttt agatattgat gtatacctac
    15481 aaccatttga atctgatata aaaaagcgaa tgaaacatta tgaggatatg aaatcaaaaa
    15541 cattgaaaaa ctataaagat tttagttctt ttgcaaatgc tcatctttac tatggatttc
    15601 atcagacaaa tgatggattc ttctataggg aatgggctcc aaatgcagat agtttgtcac
    15661 taattggtga ctttaataat tggaatagaa aatctcatcc tctaagaaaa attgggtctg
    15721 gtaattggga aatatttatt cctggtcaaa atagcttacc tcacaaatca gaggtaaagg
    15781 tacaagttac tgcaaatgga aaaacatttg accgtatacc attatatata aaaagagtaa
    15841 ttcaaaaaga ttttggtgga tttaatggac aaatatggca accaaaaact ccatttatct
    15901 ggactgacaa taattttgac ttaaaaaaca taacttctcc actaatctat gaatgtcata
    15961 taggtatgtc tactgaaagc gaatctattg gaacttataa tgaatttact gaaaaaatac
    16021 ttcctaagat aaaaaaagct ggatacaata ccattcagct tatggctatt atggaacatc
    16081 catattatgc atcttttgga taccaagttt caaactttta tgcaatctca tctaggtttg
    16141 gtactcctga agacttaaaa aacctcataa acactgctca ttcaatgggg attgctgttt
    16201 tattagactt agttcattct catgctgtaa agaatacttt agaaggaata aatgagtttg
    16261 atggaagtga acatcaattt ttccactcag gttcaaaggg aaatcatcct gcttggggta
    16321 caaaactttt taactatggt aaacctgaag taatacattt tttgctttca aatataaaat
    16381 tttggttaaa tgagtaccat tttgatggct ttaggtttga tggtgtaact tcaatgttat
    16441 atcataacca tggtcttgga gtttcatttg atagttatga aaaatatttt agtatgaata
    16501 cagatattga agctataaca tatctccaat ttgcaaatga attaataaaa gaaattaaac
    16561 ctaattcgat aagtattgca gaagatatga gtggaatgcc tggtatgtgt atccctataa
    16621 aagacggcgg aattggattt gactatagac tcgcaatggg agtacctgat ttttggataa
    16681 aaactatctc taacttatct gatgaagact gggatttggg aaaaatgtgg tatgaactta
    16741 ctactagacg acctggagaa aaaaatatag gatattgtga atcccatgac caagcattag
    16801 ttggcgataa aacaattatt ttttggctag ctgacaagga aatgtactgg aatatggaaa
    16861 taaactcaaa taaccatgtt atcaatagag caatatctct tattaaatta attaaattaa
    16921 taactttttc tctagcaggt gaaggatatc taaattttat gggaaatgaa tttggacatc
    16981 ctgagtggat tgattttcca cgagaaggca acaattggag ctataagtat gccagaagac
    17041 aatggagcct ttcagaagat aacaacttaa agtataaaca attattaagt tttgataaat
    17101 ctatgctcga acttacaaaa tacagtgata tttttatcca aaatagtcat gaacttatac
    17161 atatggataa tgataaaaag attttggtgt acagtaaggg caaatattta tttatattta
    17221 atttccaccc taatctaata caatcagttg atatttcaaa gtttcaaaat acaaactaca
    17281 aaacgatatt aaatactgat atggtagagt ttggaggaaa tacaaaaaaa gaaaacttaa
    17341 gagattatga tgtatacttt agctcaactc ctccttcttc taaaatgcct attgcctctc
    17401 gtacagcaat agtgctttta gataatggta tttaaatatg agccaaatat attaggaaac
    17461 tgcaaatata gtccagtata aggcaaaaaa ataaaataat taaaacatgg caatatacct
    17521 gttcaacatg ctaaaaagac acattgacaa atcattatgt atttgctaag ataaacatac
    17581 caaatgattg ttttgaggag tgagcttttt gggaagaaaa aaagaacctg ataatactat
    17641 acaaaaaata cttgatattt cacataagtt gttcttagaa aaagggtatg agcagacaac
    17701 gattcaagat attgtagata atttagatgg cctttcaaga ggtgctattt atcatcactt
    17761 taaatcaaaa gacgaaataa ttaaggcaat cacaagtcgg ttgtatagtg atggatttta
    17821 tggatatgat gtaaaaaatg atgaaggaaa gaccgcatta gaaaaattac aatataggtt
    17881 gcttcatgct tatgaacaac acaataaaca agacattttt ttaatgtcat catcactatt
    17941 gcgtaatcct aagtatttag ctacgcagtt tgatgagatt ataaatgata ttgtgccttg
    18001 gataaaagca ttgattgaag aaggaaatca agataattct atggaagtta aaaatccaga
    18061 gattgctgct caaatgtttg gttttcttct aaacacatgg tgtattccaa cagtttatcc
    18121 aggtaatcca caacagatga tagaacgttt tactttgttt ggtgagcaag ctgcttttat
    18181 gggtatttct tttatgaatg ataagataat gtgtgaatat caaaaatttg ttaataaatt
    18241 ttctaaatag taaatataaa actgccttaa tatcggcagt tttatattta cacaaaacaa
    18301 acatttagtt ggtattttta aaaatttaat ttatttcagt acatgcaaaa ggaggttgct
    18361 atgaacaaac taattaaaga ttgtgtaaac ttttttaatg attgtggctt ttcatattca
    18421 atatgtggtg gatatgccct agaattattt gcgaatatgc atattcgccc acacagtgat
    18481 attgacatat ggatttctga cacagataaa gaaaagagca ttcagtatat gcttaatcaa
    18541 ggatgggata tatatgagcc cttgggtaat tatttattac gacctattat cgaccttaac
    18601 aagcaacata tagaacaaat ttgtgttttt gcgattaagc ctgattgctc atttattgaa
    18661 ttaaaaaaag tcgaggatga taactataaa atgaatatac agtgtgacga acagttacag
    18721 ttcgatttta ttgaattgat atataatcca cagaaagatg gaaaatttct tttttcccaa
    18781 aatcaaagaa ttataagaga tatggataaa gccagactga taacatcaga taatatccca
    18841 tatatggctc ccgaagtggt tttgttttgc aaatcaatat acatagatag gcttggttat
    18901 caaaaagact tcgatgtaac agtcccacta ttatcacaag agcaaaggga ttggcttgta
    18961 aatgctttaa taacagcata tccagatgga catgcatgga ttgaccaatt ggcaaatcag
    19021 tattaagcct tttagctccc gaatataaca ttatgataat ccacactcta acagtttgtt
    19081 ggtttttcta gtatataaca ctcatattaa aataaacact aaaagccaaa taacaattta
    19141 aatacaaaat gttatttggc taatttagtt tgatactatt taactatctt ttacattcag
    19201 ttctataatt tccaactttt aatttgtggt attatattca tcttaacagt ttgattcttt
    19261 aaagcttttc taaatttctc agttgaagaa tctttaaaca ttttactaga agcactcttg
    19321 aggtcttcta tagattccca atgttgtatc ataatccact tttgagactt ttcatcatat
    19381 aaaagctcag tatcaataaa accagattga atagaatgaa attttaattc taagtcattt
    19441 acaatttcta taaactcttc ttttgacaaa ttttcttcca cattaaactc aactatttct
    19501 gtaataattt tcatatgtaa aacctccaat ttattttcct atatcatatc aaaaaataaa
    19561 ttggaggtat tgtaaaaaat cgacagtata attataaata gctgtacttt atattttctt
    19621 taatcgtctt attctcacca ataaatttaa ttggtgacgt ccctgaaaat tttttaaatt
    19681 cttttataaa gtgtgcttga tcatagtact cattttcata aataaaatca aaaagttcat
    19741 catctttata attataaata agttgattgc ttgccatttt aaatctgtaa attctcttta
    19801 aaatcttagg tgtataccct gtatatttta aacagattct ttccaatgtt ttaatattta
    19861 tatttgtatc atcacaaaat gcctttatat tgctatatct attaacatat ataaatgaat
    19921 ttagaagctt tacatattta tttgaaatta aatcttcttc taatatggat aataatactt
    19981 cttctaaaca taaaacaact ttttctactg attgtgttgg acttaatgac tcttctaatt
    20041 tttttgcaaa tagttttgat actgcttcta ggtcaacaat ttgtctgtta aactctgaaa
    20101 ttggtatctt taaaaatgga tataaaccaa atggataaaa agaaacccct ataacacgta
    20161 tatttccatg ttgaataata aatccatgtt tatcccttat tccattaaaa tgcatattac
    20221 tagcagtata gtcttgattt tcaattttat attccataaa atcagaaaga ttaagaataa
    20281 tatctatact gtctgtcgga agtaacttat tatttaacag tatatttgat tttgtctcaa
    20341 aataccaaat aaactttacc cacggcttta aacgaacatt tttgattgaa tatcttgtaa
    20401 ctgataacat tgtgaactaa cctctatact aaaatttttt aattatgtac tccatcctaa
    20461 tattatacag tataatttat gctatcataa attttagttc actttatatt tattttatac
    20521 attttttcaa taccttagaa ataggaagcg ctattataag acctatcaat acttgcatta
    20581 aattacctgg tattgaagta agaggtacta taaaattacc ataaagtata acttctgtta
    20641 cataatatcc aaatagcatc caaattgatg agacacatat tcctattaca ttgattaaaa
    20701 aattattccc attattacca tttgcccatg caatctttcc aagtaaataa cccataactc
    20761 ctctaactat aaaggtaaac ggtgcccata aagtccaccc agatatcaaa tcaaaaagtg
    20821 acataccaat agctcctgat aaagcacctt ttttacttcc aaatactatt gctgatatga
    20881 acaacattgc agttcccaaa tgcacaagcc caccatttat agatattggt aatcttatgt
    20941 ttataaattt agttgcaata aatactaatg ctattaatag tgaggtttcc accatgtctt
    21001 tcgttgtaaa tttttgctta gctgtaactt ccatactata tccccctatc tattaaaaat
    21061 aatacttatt aaataaattt aacaaatttc catttccttt gaatcctagt gcacttaaac
    21121 ttttatccaa aacatttagt acatgttcta ttttatttag atttgcattc tctcccatat
    21181 gacctattct taaaatagta tccatatatt gatttagtga tgttgcaaca agtgtattat
    21241 aatttttaag catataatca gtaagttcta aagctcctat actttcagga acttttatag
    21301 ctgtgactgt attagaatat ccttcttcta aaaatagttc tagaccatat tcctcaatag
    21361 attttctaac actataagct atcttttcat gtctatttaa tacattttct attccttctt
    21421 ctaatatatt atcaagtgct ttatcaagcc ccattatgtc acttattggc attgtataag
    21481 ggaagtattt tttttcataa tagccttccc atatatttaa attacaataa aaacctatta
    21541 catcagtttt tctatttttt atacaatttt ttgcatcttg acttattccg actatagtaa
    21601 gtcctgctgg tgcagaaata gctttttgtg aaccacctaa tattatatct attttagatt
    21661 catctacact taatctttct cctaccatac ctgctacaga atcaactaca gttaatattc
    21721 catattcttt aagtaatgga catattttgc ttacatcatt taatacgcca gttggagtat
    21781 cacaatgcac tactgttgca tatttaaaat tactatcctc atctaaaaat gctttcaatt
    21841 catcaatatc tatactttta gtatattcac ttgaaaaaag cacatactct ccaccataca
    21901 ttgttacaaa atctttaaaa ccttctccat atataccatt atcaattaca agtactctat
    21961 ctcctttttc tgtaagtgat gcacatgctg cttcaagacc taatattcct tcaccactca
    22021 atatgtaaac atcgtttttt gttccaatta tattaccaaa cttctcgcat gtctttttat
    22081 aaaattcaac aaaatcaata tctatatctg gatttgttgt tttttctgct cttactaatc
    22141 ttacattttc cctagtttca gttggtcctg gtgcataatt aatcttctta ttcatatata
    22201 tcagctccta tttattttct atacgattat tatacaaaat tttcatttta tatggtacaa
    22261 ttttatactt ttttagaatt gtaccggtac attttctaac atgaataata tcagtatatt
    22321 agatatatta ttgattacat aataaaatac agagcaaaca tctgcttaaa ttgtttgctc
    22381 tgtactatgc tttaacctat ttaattatga atctctttaa ctatattttt ttatatgttt
    22441 tttgctagtt aaactaacca taaatatttg tattttattc actgtatctt actctatcaa
    22501 taagagattc tttattaaaa cttcgtccta tcaaataagt tgttataaat tgagctataa
    22561 gaatacacac aatcatcaac aagattggta ctattggcaa agaatatgtt gcataagata
    22621 atccagtctt ttttagaaat ataacagcaa tataccctaa tatacctcca aatagaatac
    22681 ttcctatcat cattccagaa gtgtaataca ttgcctctga attaagcatt ttcactaatt
    22741 gtttattagt aagaccaata gcttgaagca taccaagttc tttttttcta gtaactatgc
    22801 tagttatcat tgtgttgaca agattcataa atccaatcac acctattatg cctgttagcg
    22861 tgtatcccat tatctttata aatgaaatag tagccttatt tgactcaatt ctactatcta
    22921 taaaatcagt ctctaaaaat ccattatttt tagcaatctt cttgatacta tctttgattt
    22981 cttgatactt tccttcttct gtatatattc ccaagctact agttgaatcg tatttcaaag
    23041 ttctatcaat aaaatccttc cctataccaa aacttggaac ccccatagct attgcttgaa
    23101 ctttaaattc tttttttatc tttttatctc catcatataa agttaatctt attttatctc
    23161 ctgcttttac tcccatttct tttgctgtat caacatgagt aattactatt tcatctccag
    23221 tttgaagtct ttcaagattt atttttccat ctattatatt cttgtttaat gattttacat
    23281 cattttcatt tatactttgt aaaaggtcat acttaaattc aacatcatag tcctccatac
    23341 caatttttac acttcttgca gattctattc ttttaattcc ttccatgttc tttatttgat
    23401 taaaaaaatc tttacttaga ggattatcca tttgtaaaat attcaaatta tctttaggat
    23461 ttttatcact gttcatttca taaccagata gtctaacttc tatatcataa ggaaagtgtt
    23521 ctcttgccat tttctcagca tcaaaacttt ctaaagcagt tgatactgtt ataaatatag
    23581 ttccactaag tataagtgat gccaatgtca tgtaagtacg ttttttattt ctttctaaat
    23641 tggcatgtga taatctcttt agatttatat ttttatatcc ttttctctta ctcttattac
    23701 ttattttatt tcctgtatat cttactgcgt caacaatgga tacttttgat gctactttca
    23761 ttggttttaa aagtgataaa acaacagata taaagcttat taccacaacc gataatataa
    23821 ctggtaatcg tgatgatttt acatctatat ccataaatga ttttattata atatttgcaa
    23881 gtacatagcc taaaattatt cctattggta ttgctattcc ggctaatatg aacccttctt
    23941 taaacactat attttttatt tgtttcttag ttgcaccaat tgctctaagt tttccaaatt
    24001 cttgaacctt tgtaactatt gaaatataaa atatattgta tattactaaa atactagata
    24061 atacaattac taaccctaca aaaactccac ccataatcgt ttccatatct ggttttaaag
    24121 catttatata attttcattt acagcagtat taatagtatc cagtcctata tcattagcaa
    24181 ttttatctaa tttttctttt gcttgctcta ttgataaatt acttttatca ttaaatttca
    24241 cataaatatt aaaatcttct tgtgacatat ctctagtatt tctcatatat gattctgata
    24301 taatagcata ataatattta cctgcttcag atatttcgct agtttttaag attccactta
    24361 taatgaactc tttttcaatt tttttatcac ttttatagtc atcataagat atttttatct
    24421 tttcacctaa atctttattt ttataaccaa gtgcctttaa agctccacta tctaacacaa
    24481 tttcattctc ttttgatggc aattttcctt tgataaattc aaaactattt aatttcaaag
    24541 catcttcatt catgtatgct agagaaatat ttgaatcatc ttccagtttt tcaacaccta
    24601 ctccattcat ttcaccagtt aattcaacat ctgcatgatt actcaatata tcagcctgtt
    24661 tttcatctac atttgctaat ataccttgat aattacctga atactttata gtattttctt
    24721 tttgatatgc tcctgcatca acaatataaa ttccaataga agaaagcatt aaggttgaaa
    24781 gtattatagt aattattatt agaatacttt ttgatttatt ttgctttaaa ttactttttg
    24841 ctattttagt agtattaatc atttttatca ccaaccttta acaccctgcc atcttctatg
    24901 aatataactc tatcagccat ttgggctata ctgtcatcat gagttatcat aactagagtt
    24961 tgactgtact tcttagacat agattttaat atactcataa cctcatcaga tgttttagaa
    25021 tctaggtttc cagttggttc atcagcaagt attatagctg gtcttgtagc taatgctctt
    25081 gctattgcca ccctttgttg ttgaccacct gataatgtat ttggtaaaac gtcgtgttta
    25141 ttttcaagtc ctaatgattt taaaagttct tttataaaag attcatctac ttctctacca
    25201 tctaaaccga ttggcaacac tacattttcc catacattaa gagatggaat taaattatag
    25261 ctttgaaata taaaccctat ttttcttctt ctaaatacag caagttcttc ttcttttaat
    25321 gtaaatatat ttttattatc tatatacacc ttcccagatg taggtatatc aagacctcca
    25381 atcatatgca aaagtgtact ttttccagaa cctgattttc ctattattgc aacaaattca
    25441 ccttcattta tttctaagtc aacattgtcc aaagctctta ctaagctttc tccttttcca
    25501 taatgctttg ataaattttc agtatatagt attttcataa aattatcctc tcattctaag
    25561 ttatattacc ccatatttta ttaatttttt atttctggag ctgtttatac ttatataata
    25621 aatgtagagg cttacatttt cctttcattt aatattacat agttgtaaga aacaaagaaa
    25681 acttgcttcc tatccctact tttgaagaaa ctataatatt tccaccttgt tcttctaaaa
    25741 tctttctact taaatacaat cctaccccac taccttctac agattcaatt tcatcagcag
    25801 aacctctata aaaacgttta aatatattat taaactcact tttttcaatc cctatgccat
    25861 tatcctctat tataatttta aagaaattag cagtttcttc tacagatata tttatttctc
    25921 catttacctg tgtatacttt acagcattgt ctaatacatt aaaaatactc tcctcagtcc
    25981 actttttatc atgtggtata attctactgt taaattcatt taaatttaat gttatacttt
    26041 tgctcttagc cttaggggta acacttttta ctgcatttag aatagtattt tttatatcat
    26101 tatcttcttt ttttatgttt atcatgctaa tttctaacct tgatatgttc actaaagaat
    26161 ttattaaatt ttctaattta tttatagaag ccttattggt caataagaac tcgttggctt
    26221 catcttcttc taattcttct tctataagta atgtattgta taattttaag gatgctaaag
    26281 gagtttttaa ttgatgggaa atatctgtta ctaatgattt tacactttct ttttcttttt
    26341 ctaatttaat aaactttatc tttaaacttc tattaagctc atatagacag ttatttatct
    26401 tactaaatat gccttcttta aagtattcat tatattctac tagataacca gtttcttctg
    26461 actcagtagt gtccttcaag tagttttctt gtgacatctt atctactata aaataaattt
    26521 tactcaatct tttatttatg tatcttataa aataatatat tatacctata actactataa
    26581 acatcattaa aaaaataaaa aatgattcct taaaaaaaga ttttaagtat aagctaaaat
    26641 ttttatcatt tgacatttta ttttccaatc catagccaaa tttcttaaat gccttttctc
    26701 cagtagacac cttactataa tcagaattat aaatagaatt tactatatct atttcatcat
    26761 taggatattt ttcaattaat attccagcaa tattttgagt attttttatt tgatgttcat
    26821 acaatttatg taatctacta tattcaaaaa gtataaatac aagggttact attagtacag
    26881 ataaaacaga atatacaata actcttctca ttatataatc atctttcaca cttaaaacat
    26941 ctttgaggtt catatttttt agcatttttt tatactcctt tctccccaca tatatccaac
    27001 ccctcttact gtttttatat atttaggttc agatggattt ttttcaacct tttgtctaag
    27061 tcttcttata tttactgcaa tcgtattatc atctacaaaa ttaccactac tatcccataa
    27121 agattctaac agttgctctt tggtcaatgt ctgcatagaa ttttccatca aatattttaa
    27181 tagttttgtc tctgtcttac ttaaaattat ctcttcttcc ttatcatctg ttcttataat
    27241 taatttattt tctatataat aaaagaataa atcatcacaa actaatagag tataattttt
    27301 tactgtattt actcttttca taagcgcatt cacttttgat attaatacca tcaagctaaa
    27361 aggctttgtg atataatcat ctgcacctaa atcatatcct gtgacaatat ccacctcttc
    27421 atcaagagct gtcaacatta ttatgtaaac atcacttttc tttctaatct cctcacaaaa
    27481 gtcaaaacca ctaccatcag gtagacctat atcggaaata attaagcata tctcttcttt
    27541 tgcgaaaata ttttttgctt cttctatacc aaatgcacta aaaacattgt atccttcttt
    27601 ttttaattta aaactaattc ctctatttaa agatttgtca tcttccaaaa gtaatatatt
    27661 attcatccct atatcctcca ttatcataca tactagctaa attatatcat actaataaaa
    27721 tcattttttt atcaatttgt aaatatatca gaagttgtta atatgatttc atttacttga
    27781 ataaaaacta aaaatcctca taatactatg ccatttaatg taattatttt tcataaaata
    27841 caattttatt taaaagtaat catgttaaag cataaaacaa aggaaattat tatttatata
    27901 actaatttcc tttgctgttt actattatct aaaattaaat tactatctac taatttttgc
    27961 tcattaattt ttattttgac tttttatcct ttaactcttt ttgattaaaa ttcaataaac
    28021 atatcaatgt acttgaaact ataaatataa ttatactatt tgaaaaacct aaatctcctg
    28081 ttttaggaga tttttcttta gcttctcttt tagatattcc tagattagaa ctttctctag
    28141 aacttgtttt atctaagctt ttatttttat cactatcaga gctttttata ttattagata
    28201 gattctcttc attatcattg atattttttt cattttcact taatatcaaa tcactctcat
    28261 gattcttgct tattaactca tctttagatt taataccaat tcttccatct acattttttg
    28321 atatttcttt tttgtactct atatattcaa tgactgcact ctctaaattt ccaaattcct
    28381 ttagtattgg ctcttttgaa aaacaaggaa attcatctcc acctgatgct atataatcat
    28441 tcgttgcaac tacatacttt ttatttaaat ctaatggctt tccttctttt tgaatatttg
    28501 ttattttttc gccttctttt tgtttaggat taaagtaata tgaaattcct cccacttgca
    28561 aaaaggctga acttttttct gggtaaagtt ttactccatg ctccaataca tctttaatct
    28621 gtgctcctgt aagttctttg gtaactatag tattgttaaa aggaaataca tctacaatat
    28681 ctcttcttgt tatattgcct ttttctatcg tatctcgaat attccctcca ttaaataaag
    28741 aaatatcagc cttagtttta tctagtaaaa tgtcacttat taaattaccc aaattagttt
    28801 cttttgtcct tacattttca tatgaaccat ctagagtatt tgtagttacc cctataactt
    28861 tatctaatat tttttcttgt tgttctttta tttcatcaac ctttttactt acagcggagt
    28921 caagcttata ctttaatgct tcttcttttc caattaatct aactgattta ttttctattt
    28981 ttatattttc tacatcatta gtatccagag ttagttttat ctcgccaata ttttctaaat
    29041 attgtcctgc acttacaatc aatgtatcac ccacttgttt accattttca aacttagtgt
    29101 ggctgtgtcc atcaataatc aaatcaattc cttgaacctc atttgctata tctatactat
    29161 ttggcttact taaactattt gtaccaatat gacatattgc aactattaca ttggcacctt
    29221 ttccttttaa ttcatttact tgttctgttg cactttctat aggattttta aactctaatc
    29281 cttccacatt tttaaatcca gttttgctct ttgtttcctg ggttgagagt ccaaaaaatc
    29341 ctatttttat tccatctatt tcttttatat cattactatc aaaaactttt tttccatttt
    29401 caaaaatatt tgatgataaa aattttaaag tatgctctcc taaattagca cttttagata
    29461 actcaaacag tctatctttt ccataattaa agtcatgatt tccaggagta atatagtcat
    29521 atccagcaca tttaattaat tcaattgcac ttttccctct atccatattt actattggaa
    29581 gtccatgcaa acaatctcct gcatctacta aaattgagtt tggagtttct tttttcaatg
    29641 tggctagatt tcctatttgt atatggtcat caccttcagc atatcttcca tgtatatcat
    29701 tagtgtgaaa aatggttatt tcttcaaatc gctctagccc ataagaaata aaactctgac
    29761 ttgttgtaat tagaattata attaccaaaa ttaaatacct tctaatcttc aatataaatt
    29821 agcctcctca aattagtttt agctttaata taaaatttat attttacata aaacttttta
    29881 gataaatatt aaactatagt aagattaatt agtgtaattt ttaatattta tctatca
//
LOCUS       DAEPXW010000046        29358 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.047, whole genome shotgun sequence.
ACCESSION   DAEPXW010000046 DAEPXW010000000
VERSION     DAEPXW010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29358
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.047"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            50..166
                     /gene="rrf"
                     /locus_tag="KRM55_002043"
     rRNA            50..166
                     /gene="rrf"
                     /locus_tag="KRM55_002043"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            286..477
                     /locus_tag="KRM55_002044"
     CDS             286..477
                     /locus_tag="KRM55_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBH1594284.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            632..2041
                     /locus_tag="KRM55_002045"
     CDS             632..2041
                     /locus_tag="KRM55_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1594285.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            2172..2861
                     /locus_tag="KRM55_002046"
     CDS             2172..2861
                     /locus_tag="KRM55_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBH1594286.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2864..3799
                     /locus_tag="KRM55_002047"
     CDS             2864..3799
                     /locus_tag="KRM55_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBH1594287.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3796..4689
                     /locus_tag="KRM55_002048"
     CDS             3796..4689
                     /locus_tag="KRM55_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBH1594288.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4767..5513
                     /locus_tag="KRM55_002049"
     CDS             4767..5513
                     /locus_tag="KRM55_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBH1594289.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5514..6347
                     /gene="rsmI"
                     /locus_tag="KRM55_002050"
     CDS             5514..6347
                     /gene="rsmI"
                     /locus_tag="KRM55_002050"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBH1594290.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6370..7074
                     /locus_tag="KRM55_002051"
     CDS             6370..7074
                     /locus_tag="KRM55_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBH1594291.1"
                     /translation="MEIGKIIIESLKREDTHKIFTELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7262..7690)
                     /locus_tag="KRM55_002052"
     CDS             complement(7262..7690)
                     /locus_tag="KRM55_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH1594292.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7727..9157)
                     /locus_tag="KRM55_002053"
     CDS             complement(7727..9157)
                     /locus_tag="KRM55_002053"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBH1594293.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9289..9873
                     /locus_tag="KRM55_002054"
     CDS             9289..9873
                     /locus_tag="KRM55_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HBH1594294.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9889..10410
                     /locus_tag="KRM55_002055"
     CDS             9889..10410
                     /locus_tag="KRM55_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HBH1594295.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10476..10722
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10806..12743
                     /gene="metG"
                     /locus_tag="KRM55_002056"
     CDS             10806..12743
                     /gene="metG"
                     /locus_tag="KRM55_002056"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBH1594296.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKGELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGEPYVLPFTQGAKDGCEVR"
     gene            12773..13543
                     /locus_tag="KRM55_002057"
     CDS             12773..13543
                     /locus_tag="KRM55_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBH1594297.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13881..14312
                     /gene="phnG"
                     /locus_tag="KRM55_002058"
     CDS             13881..14312
                     /gene="phnG"
                     /locus_tag="KRM55_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBH1594298.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14327..14902
                     /gene="phnH"
                     /locus_tag="KRM55_002059"
     CDS             14327..14902
                     /gene="phnH"
                     /locus_tag="KRM55_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBH1594299.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSTINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14905..15990
                     /locus_tag="KRM55_002060"
     CDS             14905..15990
                     /locus_tag="KRM55_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBH1594300.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFISELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            16010..16879
                     /locus_tag="KRM55_002061"
     CDS             16010..16879
                     /locus_tag="KRM55_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBH1594301.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16872..17738
                     /locus_tag="KRM55_002062"
     CDS             16872..17738
                     /locus_tag="KRM55_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1594302.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17779..18492
                     /locus_tag="KRM55_002063"
     CDS             17779..18492
                     /locus_tag="KRM55_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1594303.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18493..19662
                     /locus_tag="KRM55_002064"
     CDS             18493..19662
                     /locus_tag="KRM55_002064"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBH1594304.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVLNTIVNGKTVYKREV"
     gene            19666..20502
                     /locus_tag="KRM55_002065"
     CDS             19666..20502
                     /locus_tag="KRM55_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH1594305.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILSITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20503..21498
                     /locus_tag="KRM55_002066"
     CDS             20503..21498
                     /locus_tag="KRM55_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1594306.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21516..23204
                     /locus_tag="KRM55_002067"
     CDS             21516..23204
                     /locus_tag="KRM55_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH1594307.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23216..24283
                     /locus_tag="KRM55_002068"
     CDS             23216..24283
                     /locus_tag="KRM55_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1594308.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24720..25715
                     /locus_tag="KRM55_002069"
     CDS             24720..25715
                     /locus_tag="KRM55_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1594309.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHDGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSDIDKKVRDILEVVELSGYDKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIKSLHRKLGITTIMVTHDQEEALCLADKMVVMNNGEVIQIGTP
                     KEVYKSPKTPFVADFIGTINFIDDDVNMIAIRPEDIKVEFNRDFKEIDVKVGEILDIE
                     FRGFNYRITVEYCSKQIKLDVVSKVVEQMKLCVGSKINFKIPKERTIQYKSEGCA"
     gene            25733..27421
                     /locus_tag="KRM55_002070"
     CDS             25733..27421
                     /locus_tag="KRM55_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH1594310.1"
                     /translation="MITIKNKRRISDSKIQKCFLVFLVIALVVFILFPLISLLKNAFM
                     DTSGSFVGISNFSKYIENPTLIASFKNSIFVSTISSLISLCLAFIYSYAITRTNIRFK
                     NFFKTMGIFPLFAPAMLYGISLIYLFGNKGIFTIIGIEVPLYGPLGIIICQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFFKITIPGIKYSLVSSFFVSFILAFTDF
                     GAAKIVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTVDKIASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIACSFITLLIFILIFVSVIGSVIKLWPYDLSFTMEHY
                     TFKGISGNGIKTYLSSLKISILTAIFGTIFVFFSAYMIEKVDKFPRLRQISYFLSMIP
                     MALPGLALGISYITFFNSASNPLNFLYGSTTIMVIANIVHFYSVCFITSNSSLKMLDR
                     EYELVAKSINIPFYKVFFYVTLPMSITSILEVAVYYFVNSMVTVSALIFLYIPQTQTA
                     SISILKLEEIGYIGPSAAMAVLVFLTNIIVKLLYELTTKKLKTKTQKWQQKEVA"
     gene            27433..28500
                     /locus_tag="KRM55_002071"
     CDS             27433..28500
                     /locus_tag="KRM55_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1594311.1"
                     /translation="MKFRKLVSLGILSTLLLSVITGCNNASSGSNLKSNNKIKGELTV
                     YTAIEEDSIDTYLTTFKEKYPDIKLNVLRLSVGDITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPVFKDDKKVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            28692..29222
                     /gene="rnmV"
                     /locus_tag="KRM55_002072"
     CDS             28692..29222
                     /gene="rnmV"
                     /locus_tag="KRM55_002072"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBH1594312.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
BASE COUNT        11682 a         3281 c         5244 g         9151 t
ORIGIN      
        1 ttctataaac ttattaaaaa cttaatagaa atattaagca taaagattat gtggttacaa
       61 tagcagagag gatacacctg ttcccattcc gaacacagaa gttaagctct ctagcgctga
      121 tggtacttgg tgggaaactg cctgggagag taggacgtag ccacgtaatt ttttttattt
      181 tttgtcaaaa aaaacaaaaa atacgtattt cttttttcat ttcgggaaaa ctaaacacag
      241 gaattatgga ctttataaaa atttaattct tgaggagtga tataagtgaa aaaagttgct
      301 ttaattttag ctataatagg tgcgcttaac tggggtgcaa ttggtattct aggtacagac
      361 ttaataggta gtatctttgg tggaacatat gaaatggtaa gtagaataat atacttcatt
      421 gtaggtttag ctggattata cttaatacca agtttaatgt ctgatgatag agaataattt
      481 atgcttttat gttaaatacc tcattctaaa tgtttagaat gaggtattta attttataaa
      541 aatattaatt tgtttctttt ttaatggtaa aatagataag aattgaagtt ttaaaaagaa
      601 gtattatgta aaaaaggagt actattaata tatgtttatt attaatgaat taaataagat
      661 tgtaaatgaa gaagtaatat cttttcatat gcctggtcat aaaaagggac aggtttataa
      721 aaagttagga tataaagata tactaaaaaa tttgtataaa atggatacaa ctgagatatt
      781 aggaacagat aatttacact ttccggaagg aattataaaa aattcacaaa aaaaagcatc
      841 aagagtattt aaaagtgatt atacttgcta tttagtaaat ggtagtagct gtggaataca
      901 atctgcaata atgtcagtat gtagtcctaa aagtaaaata ataacaaata gagactgtca
      961 tcagtctgtt ataaatggat gtattttagg agatatagat atagagtatg tgccttgtga
     1021 gataagtgaa gagacaaatg tcttaaaagg gatatctata agtaatgtga ttgatataat
     1081 agataaaaac ttggatgcaa aagcagtact gcttacttat cctacatatt atggaatgac
     1141 atatgattta gaatacatat gtaattatgc acatagcaaa aagatggtag tgatagtaga
     1201 tgaagcacat ggtgcgcatt tagggcttag cgagaggctt cctaaaacag ctcttgagca
     1261 aggcgcagat atagttgtac agagtacaca taaaactctt ccagcattta cacaatcgtc
     1321 aatgatacat atacagggag accgagttga tatagataaa atattgaaca tgttaagaat
     1381 tacagaatct tcaagccctt catatttatt attatcttct ctggaattag cagtagatat
     1441 atatgaaaat aaaggaaaag aattaatgga agagctttta aataatatta taactttcaa
     1501 aaataaagtt gattcaaata ttaatatata cgacacaaat gataaaacaa aaatatttat
     1561 atcatctaaa aacatgggtt taacaggtta tgaactagaa aatattttga gaaataaata
     1621 taacatacaa gtggagttat ctaattatta tggagttctt ttaatatgta caataggaaa
     1681 tactgctgag gatttctcta gtttagaaac agcattaaac aatgttgtaa aggaagactt
     1741 taaatttgaa aagttagaaa ataaaaaata ccctgttgtt attccaaaga aaatattaac
     1801 acctagagaa gcattttata aaactaaaaa aagtgttaaa atatatgaca gcataggtaa
     1861 agtttgtggt gaatgtatag ttccataccc acctggaata agtgtaatat ctcctggtga
     1921 agtaataagt aaagaaataa tagactatct aatgttttgt cattctaaag gcatgattgt
     1981 gagtggattg aaagatgtag atttaaattt tatacaagta atagatttag aagacattta
     2041 aaaattatga tataaaagta gatagaagta gatagtttaa aattgtgaag agaaataaat
     2101 aaactgctta tatagagcta tctaataaaa gtactaaaaa agtaaaaagt gtttgtatgg
     2161 aggatatgaa aatgaaaggt aagttaataa ttatagagag tggttcagat gcaagtggaa
     2221 aggctactca gacagaaata ttatatgaaa gattaaaaaa agaaggctat atgattaaaa
     2281 aggtagaata tccaaattat gaatctccat catctgcctt ggtgaaaatg tacctaaaag
     2341 gagactttgg taaaaatgca tcagatgtag acccatatat agcatcaact ttttttacag
     2401 ctgataggta tgcatcattt aaaaccgatt gggaggagtt ttacaatgaa ggtggaataa
     2461 ttatcgcaga tagatataca acctctaata tggtacatca ggcctctaaa atggatattt
     2521 gtgatagaga agagtattta aattggttag ctgattatga atttaattta tttaagatac
     2581 cacaacctga ttgtgttata tttttagatg tgcctattga atttagtaaa aagcttatgg
     2641 agaatagaaa aaataaaatt acaggggaag aaaaaaagga tattcatgaa agtgacatag
     2701 agtatttaga gaaatcttac aacaatgctt tatatatagc agataaatat gattggaaaa
     2761 aaataaattg tgttttagat aacaaattaa gaagtattga aagtatacat aatgaaattt
     2821 ataaaatagt tcttgattca ataaaaccta tggagagata aatatgtatt ttgaaaatat
     2881 tatagggcaa gattttgcaa agaaatattt aacaaattct ataaagaaaa ataaacttaa
     2941 taatgcgtat atgtttgaag gaatggatgg aataggaaaa aagaaatttg cagatgaatt
     3001 atcaaaacta ttacttgatt atgaaaatct cgaaaatagt ccagactatg tactcataaa
     3061 accagatgga aatagtataa aaatagctca aatcagaaat ttacaatcag atatagtaat
     3121 aagacctcat aaagactata aaatatatat aatcaataat gctgaaaaaa tgactgtgga
     3181 agctcaaaat gcacttttaa agacgctaga ggaacctcca aactatgcta taataatctt
     3241 agtcacaaac aacaaggaat ctttattaga aactataaaa tctagatgtg atataataaa
     3301 gttctcacct ataccaattg aagacttaaa acgttatttg ataaatacag gtatagaaga
     3361 agaaagagct caattattgg ctattttttc gagaggaagt attgagaatg ctctaaatct
     3421 atctcagtct tctgagtttt caatgatgag agaagatata caacagtata ttcagataat
     3481 gttagataaa aacatagtgg agattttaaa tataccaaat aatatggaaa aatatagagg
     3541 taagattata gctttattag atatgatgat aaactatttt cgagatatca tcctattaaa
     3601 agaaaatgta aacaagaaca tgttaataaa tgtagataag ctagttttca ttcaaaatat
     3661 gagtggaaaa attagttatt ctcaattgtc caagattatt gatataatag aagatgcaaa
     3721 gagtaaaata aaaagcaatt gcaatttcaa tataagcata caagttatgt ctttaaatat
     3781 atacgaggtg attaaatgat aaagatagta ggtataaggt ttaaaagtgc tgggaaaata
     3841 tattattttg accctgttga ttttaatata gagcaagata tggatgtagt tgtagaaact
     3901 gcaagaggct tggagtatgg gaaagtagtc gttggtccaa aagatatgga tgaaagcgaa
     3961 ttagtttctc ctttgaagcc aattataaga atagctacag aagaagataa aaaagtatat
     4021 ctagaaaata aggaaaaggc aaaagaaact tttgagttgt gccaacaaaa aataaaagaa
     4081 catgagttaa caatgttttt aatagattgt gagtatacat ttgataggaa taagttgatt
     4141 ttttacttta cagcagaagg aagaatagat tttagagaat tggtaaaaga cttagctgct
     4201 atatttaaaa ctagaataga acttagacaa ataggtgtca gagatgaagc taaatctata
     4261 ggaggtctag ggccttgtgg tagaaaactt tgttgttcat cttggttagg tgattttcaa
     4321 ccagtttcaa taaaaatggc aaaagaccaa agtctatctc taaatccaac aaaaatatct
     4381 ggaatatgtg ggagattatt ctgttgctta aaatatgagc atgatgtata tagtgaagca
     4441 atagaaaaaa tgcctgttgt aggtgcattg gtgcaatcag atgatggaaa aggaaaagtt
     4501 gtagaagtga atcctttatt agaacaaatt aaagtggaat ttcaagacaa gacagtaaag
     4561 atatacacaa gagaagatat aaaaatactt agagagccta aaaaatgtga tggctgtggt
     4621 ggtaaatgta aggataatga tggattagat gaagccacac taagagagct aaagaaatta
     4681 gaagattaaa tttaaggtag ggcttttcct acctttttta aagcaattaa tgcttaaagt
     4741 tattaatatt tgaggagaat ttatatatgc aattaaaaga ttcagaaaga atagatgatt
     4801 tacaattaaa aggccttaaa attatacaag atactaatgg tttttgtttt ggtatagatg
     4861 cagttttatt agccaatttt actaaaataa aaaaagatgc caaagtagta gatttgggta
     4921 ctggaactgg aattatacct attttgatag ctggaaaaag tgaagctaaa aaaattattg
     4981 gcgtggaaat acaagaagat gtatatgaaa tggcaactcg ttctataaaa ttaaatggat
     5041 tagaagaaag agttgagatt ataaatgaag atataaaata catagacaaa gtcttagaca
     5101 taaatggtta ccatgtagtc acatcaaatc ctccatatat gcatattgat ggaataaaaa
     5161 atccaaatga taaaaaagca atatcaagac atgaagtaag gtgcaatttg gaagatgtaa
     5221 ttagagctgc atccagattg gttatgccta gaggaaaatt cttcatgata catagaccaa
     5281 caagattggt tgatataata actttaggga gaaaatataa attagaacca aaggttattc
     5341 aatttgtgca tccaagacct caaaaagcac cgaacttagt tttggttcaa tttgtaaaag
     5401 atggaaggcc agagcttaaa atattggacc cattgtatgt ttatggagaa gatgggaatt
     5461 atacaaaaga attaaaagca atatataata ataaagatat aggagagttg taaatgagcg
     5521 ggaaattgta catatgtcca acaccaatag gaaacctaga agatataaca tatagaactt
     5581 taagaacatt aaaagaagta gacttgattg cagcagaaga tacaagacat agtataaaac
     5641 ttttaaatca ttttgaaatc tcaaaaccac taactagtta tcatgaacat aataaggatt
     5701 caaagggaga ttatttgata aataaactaa ttgatggtga aaatatagct ctgataagtg
     5761 atgcaggtat gcctggtata tctgacccag gagaagagat aataaaacaa gctatacaaa
     5821 ataacataga gatagaagta ttgccaggtg caacagcctt tgtaacggct ttagttggct
     5881 ctggtatgga cacacataga tttgtttttg agggcttttt agatagagat aaaaaagtta
     5941 ggaaagcaca attggaagaa ttaaaggaag aaagtagaac tataattttc tatgaatcac
     6001 cacatagatt gaaggataca ctaaaagata tgcttaaaat tcttggtaat aggaatattt
     6061 ctataaatag agaacttaca aaaaaatatc aagaaataat aagagaaaat atagaaacta
     6121 ccataaaaat atttgaggaa aaagaagtaa gaggagagtt tgtattaata gtagagggtt
     6181 ttcatggtga gaagtcaaag aaagaaaatt atgatgggct tacagatagg gaatatgttt
     6241 taaaactaat tgaaagtggt atgaacaaaa aagatgcaat aaaaatagtt tgtaaagata
     6301 gaaagttaaa gaaagatgtg gtttataaac aagttttaga tttataaaac ctgaatctga
     6361 ggtgatttta tggaaatagg gaaaattata atagagagtt taaagaggga agatacacat
     6421 aaaatattta cagaattaga taataagcat gaattagaaa aaataattcc taaaataagc
     6481 tgtatgaagt ctgtaggtga atgtaaatat catgtagtaa attgttttga acattctata
     6541 aatgcattaa aagaattaga aatagtatta aatgataagg atttttttcc aatacatcta
     6601 agaaaacatg tgtcaaacta tttaaacaca tatattgaag aaggaataaa taagttacat
     6661 gtattaaagc tgggaacatt tttacatgat ataggtaagc ctgacagtat gaccttagat
     6721 gaaaccggaa gagttcattt cacaaatcat gaaaaaatag gtgctcaaat aattgacaat
     6781 atgggaataa agttagagtt atcaacagag acatatagac ttataagtaa atatgtaaga
     6841 tatcatatga tacttttgtc tctatataag aaaaatgatt tgagtaggaa agaattaatt
     6901 aatgtattta acttagtaga tgaggacact ataggtgtaa taatgcttgg gtatgcagat
     6961 atagtgtcta cagtaaaatt attgggtaag agtggagaag tcagtgtgtt aaagacatat
     7021 atggaatata ttttaacaaa ttacttgtat aagagtaatt atacacatgt ataaatttag
     7081 ttaatataat tgagttttag atgattaatt aaagtttgaa atatacggat ttcaaaaaca
     7141 taaaagaagt tgtctttgtt gtaaaattat gaaagacaac tttttttata tcaaaaattg
     7201 aaattttatt aaggatactt aatggtctat taattaataa accattagta tttaatttat
     7261 attacaatat tgattttgct tgtattggcg ttgatagtat aacagaggtc ttagtagaac
     7321 caattttctt tatagtatca atcacatttt ctagctcgta catatctttt acaattactt
     7381 ttaaaagtaa gcaatcatca cctgttatat ggtgacattc tacaatccta gggtcctttg
     7441 cagctgactc aataaattct gtatatccat tgcttggaag agaaatatga ataaatgcct
     7501 ttataactct gcctaatgaa tctgggttga caatagcttt atatccttct ataacaccag
     7561 actcttctaa tcttttgact ctttctgaaa ctgcaggaga agttaaacca actatttttc
     7621 ctaagtcctt catagaaatt ctcccatcat cctgtaaaat ttctatgatt ctgtaatctg
     7681 taacatccat aaataaacag tcccccttaa ataaaaataa ttaatgctat aaaacttttt
     7741 tagaatctat catttgtgtt tttaaatacc aaagatttct agataaatca accttataaa
     7801 tgtgtggttt tgaaagtctt ttgtattgtt cccagatagt acttaattca tattgtacat
     7861 gattttttat ttcaagaaca gcttttttat tatatttgca tctgcctttt atatacaatg
     7921 gtttaagaag ctctttaact ttgtaatttg taaatacctt cgttttccat gtataagtag
     7981 gatggaagat ttctaaaggt ttagactcat ctataacttc atcatgtaac ataatcaaat
     8041 ctgcctctgc cttattgtct tcgttatata ttcttataac tttcttgtaa ccaggattat
     8101 ttattttttc tggattctca gaaatcttta tcttaggttc aagaactcct ttttcacaag
     8161 atgcagctaa tttataaact cctccaagag aaggtgaatc gaaagatgta atgagctttg
     8221 tacctactcc ccatgaattt atagtagctc cttctgcttt aagtgatgtt atggtatatt
     8281 cgtctaggtc attagatgca gtgatgctga tatctgaaaa gccagcatta tctaattgtt
     8341 ttttagcttc tttagataaa taagctaaat ctccagagtc aagtcttata cccataggtt
     8401 tgtatccttt ttcagaaata tttttgaata cttttattgc attaggaact ccactattta
     8461 atacatcata agtatctaca agtagtaggc atttatctgg ataaacatca gcatatgctt
     8521 ggaatgcttc aagttcatta tcaaattttt gaacccaact gtgagcttgt gtaccaatta
     8581 taggtatatc aaacattttc cctgctagta cgtttgcagt tccagcacaa ccaccaacta
     8641 cggcagccct agctccatat atccctgcat ctggaccttg tgcacgacgt aatccaaatt
     8701 caaatacagg gtctccttga gctgcaaagc aaactctaga tgctttagta gcaataagag
     8761 actgaaaatt aactattgtt aacaatgctg tttcaataag ttgagcttga tataaaggtg
     8821 ccttaacagt aattaatggc tcattaggga acatgatagt tccttcctca acagcatata
     8881 tatctcctgt gaatttaaat tcttttaaaa attttaagaa cttgtcagaa aataaattta
     8941 agttttttaa gtactctaaa tcttcatctg aaaaatgaag attatctatg tattcaacaa
     9001 cctgatcaat accacaaact atagtatacc ctccatcaca agcgtttttt ctaaaaaaca
     9061 tatcaaatac aacaatgtct tcatgaatat tcttttcaaa atagccattt aacatagtaa
     9121 gctgatataa atcagtaaga agtgttagat ttctcattat ttctctcctt aattattatt
     9181 aaatattaaa aattgtaaaa actcccacac ttatactaaa acataatata gtacaacttt
     9241 caagtataaa gtattaccta actatcataa aattatttaa agaggaggat gattataata
     9301 ggaaaaatat ggttttatat ggtatcgata ggaataatag gaagcttgat ttctaaaaat
     9361 atgggtgaat taaataaagt tatattaagt gaaacatcaa aaggtataga gtttgcaata
     9421 agtctagctg gtatcatggc actctggatg gggataatga atatcgcaaa agaatcaggt
     9481 ttaattgaaa agataggtca aaaactaaat cctataatga gaagattatt tccttctatt
     9541 ccaaaaggtc ataaagcaat gtcttatata gttatgaata ttgctttaaa tatgttgggt
     9601 gctggaaatg gtgcaacagc atttggttta aaagcaatga gtgagcttca aactttgaat
     9661 aacaagaaag atacagccac taatgatatg attatgttta tggtaatcaa tatatcatct
     9721 atacaaataa ttccatttac tataatcaaa ttaaggatgg atatgggggc tcaaaatcca
     9781 agtgaaataa tttttacgac tttatttgca accataatat ctacagcagt agcaataata
     9841 acatgtaaat tttttcaaag aagatataga taaaggggat gtagatacat ggagatattt
     9901 tcaaacttac ttataccaat aataattctg tacatagtaa tttatggtaa atataaaaaa
     9961 atagatgtgt atgatagttt tgtaaaagga gcaattgatg gattaaaagc tgcatgggat
    10021 atcctaccat atataatagg tatatttttg gcaataggaa tattcaaaac tggtaaaggt
    10081 cttgatatgt tagaatggct atttacacca atagcaaata tgatgagtat accaaaagaa
    10141 ttaataggtc taataagtgt aaaaccttta tctggaagtg gtgctttagg gatgtacagt
    10201 gaacttgcaa atagagttgg aataggaagt ttagtagaaa aaatgggtgc tacgattgta
    10261 ggttcttctg agactatttt ttacacaatg gcaatatact atggaagtct gaagataaaa
    10321 aatactagac atacattatc atgtgctatg attagccatg ttgcaggtgt catagcagct
    10381 gtttttattt gctatgtaat atttgtataa tttgttgaca atatgggaaa aattttataa
    10441 tatagtgatt atatagaaac aaatagtaat acaaattaca agctatgaaa agaagagtaa
    10501 ataaaggttt tttctatcag agagctaggt taggtgaaag ctagtgtcaa aagctttatt
    10561 gaagatggtc ttggagcttt ttatctgagc aagtgtgcta gggtaaaacg gttggacacg
    10621 ttatagtcta ctaaggtatc tataaaatgt ttctacattt catgtgaaac ataactatta
    10681 tagatgaatt agggtggtac cgtgaataat ctcgccccta tgttaactca taggaggcga
    10741 ttttttatta tttaaatgaa agaatcatat gattacgaac gataaaaaat taggaggtaa
    10801 ataacatgag caaaccgagt ttttatgtaa caacaccaat atactatcca agtggaggat
    10861 tacacatagg acatacttat tcaacagtag ctgcagatac aatagctaga ttcaagcgtt
    10921 tctgtggata tgatgtaaag ttcttaacag gaacagatga gcatggtgaa aaaattcaaa
    10981 agaaagccat agaacaagga atgtcagaga tagagtatct tgatggaatg ataaaagata
    11041 taaaggcctt atggaatact atggatatat cttatgatga ttttataaga actacagaaa
    11101 aaagacatac agacataata caaaagatat ttactaaact atatgagcaa ggtgatatat
    11161 ataaaggtga atatgaaggt agatactgta ctccttgtga gagtttctgg acagaatctc
    11221 aattactaga aggaaataaa tgccctgact gtggaagaga aacatattta gtaaaagaag
    11281 aatcttattt ctttagatta tctaaatatg aagacagatt aaaagagtta tttaaagatg
    11341 atagtttctg ttttcctgct gctagaaaaa atgaaatggt ggcaaacttt ttagacaaag
    11401 gattagaaga tttaagcgta actagaacga cttttgactg gggtataaaa gttccttttg
    11461 atgaaaaaca tgtaatttat gtgtgggtag atgctttatg taactatata acagcattag
    11521 gttatatgac tgataatgat gaagaattta aaaaatattg gcctgccaat gttcaaatag
    11581 taggtaaaga aatagtgaga ttccatacaa taatatggcc agcgctttta atggctttag
    11641 gtctagaagt tccaaaacaa gtatttggac atggatggat actatttgct gatgataaaa
    11701 tgagtaaatc aaagggtaat gtggtttatc cagaacctat aatagaaaga tatggaatag
    11761 acacacttaa gtacttctta ttaagagagt ttgcatttgg gcaagatgga agttatactc
    11821 atagaaattt tgtaacaaga ataaattatg atttagcaaa tgatttagga aacttaataa
    11881 gtagaactgt agctatggtt gaaaaataca ataatggtat aataccaaca gcaaaagttt
    11941 caactgattt tgatgctgac ttaaaagaac aagctgtttc aactagagaa aactttgaag
    12001 ctgaaatgga taaaatgcaa ttccatgaag cattagagag tgtatggaaa ttagttagaa
    12061 gaactaacaa atatatagat gaaactatgc cttgggcact agctaaagat gaaacgaaga
    12121 aaggtgaatt agacacagtt ttatataatt tatgtgaatc tataagaata atcgcaacac
    12181 taataaatcc tataatgaat gagactgcta ataaaatata tgaacatata ggaataaaag
    12241 gtcaagatga tataactaca tgggaaagta caaaaacatt tggtcttatt ggagaaaatg
    12301 taaaagtatt taaaggtgaa cctttattcc caagattaga tgtagaaaaa gagatagaag
    12361 aattaactaa aatgttctct gggaaacctc cagtagaaga aaaaccttta gagcataaag
    12421 aagaaattac tattgatgat ttagacaaaa tagagcttag agtagggaaa ataataagct
    12481 gtgaaaaaca tccaaaagca aataaattat tagtatcaca agttaagatt ggaccagaaa
    12541 caagacaaat agtatcagga atagctgaat actataagcc agaggattta gtaggaaaag
    12601 aggttacagt ggtatgtaac ttaaaaccag ttaaattaag aggtgtagaa tctcaaggta
    12661 tgatattagc agcaggtgat gatggagaac catatgtttt accatttaca caaggggcta
    12721 aagatggatg cgaggttcgt tagtaggtaa ttaaatagta aggagattaa agatgttatt
    12781 tgactcacat gcacatttaa atgatgaaag ttttgatgaa gatagagatg aacttattgg
    12841 ttcattaaaa gataaaggtg tagatttggt tgtaaatcca ggagcagata tagagacgtc
    12901 gataacagca attgaacttg cgaaaaaata cgactttata tattcagcag ttggggtaca
    12961 tccacatgat gtatcaaaac tagatgatac agcaatagaa actctaagaa aacttgcaac
    13021 tgagaatgaa aaagttgtag ctattggaga gattggatta gattattatt atgattattc
    13081 tccaagagaa gaacaaaaag agtggtttaa gaagcaaatt gaattagcta atgagctaaa
    13141 acttccaata ataatacatg atagagatgc acatggagat acttttgaga taataaagaa
    13201 tactaaaaat cctgaaatag gatgtgtact tcattgttat agtgggaatg tagagttagc
    13261 tagagaatat gttaagatgg gttgttatat atcaattcca ggcacggtta cttttaagaa
    13321 taataaaaaa actagagaag tagtaagaga aatacctcta gaaagattat tcatagagac
    13381 tgattcacca tatatgtcac cagagccaca tagaggaaag agaaacaatc cttcccaagt
    13441 atcttttgtt gctgataaga tagcccagga aaaagggata tcttatgaag aagtatgtag
    13501 agttacaaaa gaaaatgcaa agaaattttt taatataaaa tagacaaatt aaatcttata
    13561 atgatatata taataagtca ttataagtat aggatgagag tgcctcaaaa tgagtttttt
    13621 agttcatgag gcactctttt ttttatgaaa tcaaatatat tttcatcatt tcaacaatga
    13681 aaaagaagtt tatcatattt tgagatagtt tgtttttatt tatttaattc atattttaaa
    13741 atatattttc ttaacattgt taaaaaagaa tttacaagat attcattaga attaactcaa
    13801 ctctaatatt cacttaactt aagttgttta ttatattatt aaagagaagt aaacgaaagg
    13861 tagattaagg aggttgaatt ttgtatacag ttgatagtac taagatattg ataaatatga
    13921 acttagagaa actagaaaag atatactcaa tgataaaaga tacatcaagt atttctataa
    13981 ttaaagaacc taacttggct acagtaatgg taagagctaa tgaaagtgta aaaaacacaa
    14041 catttaattt aggagagata ttagttactg aatgtagtgt aaaggtagat gaaagcttgg
    14101 gttacggaat agtttcagaa aacaataata agaaagccat ttacttagca gttatagatg
    14161 cagttttaca tagcaataac agtaaatttg atgagttaaa gaattacata aataaaagtg
    14221 tatatgaaga gaacttaagg tatgaacaag agattattga tgaatttagc ttgattaata
    14281 aaacgaaagt tcaattcaat gctatggatt aaataggagg agaatcatgg taaattatac
    14341 acaagaaata tatagaaaga tgctagatag tgcttcattt cctgggaaat taaataatat
    14401 agataatata aatatagaaa ataatacaaa actattgaat ggagcaattg gtatagcaat
    14461 cactttatta gaccaagaag ttaccttcta tatagaaaat tatactcaaa aagatataaa
    14521 aaatataaga gcgcttacaa tgtcaaatca aatagattat agaaaatcag attatatatt
    14581 tttagatatt aattcagaag tggatatatt acagattaaa ataggttctt ttgaatatcc
    14641 tgatgaaagt gcaactatag tacatcaagt aaatgattta tcaacgtact ctcaaactaa
    14701 gtatataaag cttgatttga gtggtcctgg tataaaatct aaaaatagta tatatataaa
    14761 tggaattaga gaagaattta tagaaagatt atctaccata aataaagatt atccaatagg
    14821 aatagatttg attttagtag ataaaaaagg agaaattgca tttataccaa ggtcatcaaa
    14881 attaagttgg gaggtattgt agaaatggct tatgtagcag ttaaaggtgg agaagaagcc
    14941 atattacagg ctaaaaatat acttgagttt tatagggtaa aaggagatag cttgcctata
    15001 gatgtaaagc agattgagga acaaatgtct tatgctgtag acaaagtaat gtctgaagga
    15061 agtttataca acaaggaact atcagcattg gctataaaac aagctcaagg tgatatatta
    15121 gaagcctctt tctatgtaag agctttaagg tcaacaatgc ctagaattac atattcagaa
    15181 cccataaata cagaagaaat gagaataaaa agaagaatat cagctacttt taaagatata
    15241 ccaggaggtc agtatcttgg ggcaactaga gactatgaaa atagaatatt aaatgtagaa
    15301 ttattagaag aagatgaaaa aaagaataga gattttagag atagttttat aagtgaatta
    15361 gaaacagtag atgaaatccc tgaatttaca aaaatatcta atatatttag aaaagaaaat
    15421 ttattacaag aagaagtttg tgaaaacaaa ttggaagaag ttattgatga tattacaaga
    15481 aatagtttaa gatttccagt ttctaggtca gcaaagttac aggcattaac tagaggtgaa
    15541 agtggagtag tgtcaggttt tgcttatgct attgtaagag gttttggtga tgaacatcca
    15601 tatataagtg aacttagaac tggtaatgta tttataaaag taaaacatcc catctatgaa
    15661 gatgaagaaa taataatagg tgatatgctg gttactgaat gtgaaatagt ttcaaaagca
    15721 tcacaaaata agactgaaaa ttctaaaact aattcggaag ataaaaataa gatgtcttta
    15781 ggatatggtc tttgtatggg gaataatgag aataaggcta tatctatggc catactagac
    15841 aaatctttgg agccaaatag tgaaaaacta gcacaagatg aagaatttgt attgcttcat
    15901 atagatggaa tagattcatt aggatttata tctcacttta agcttcctca ctatgtagat
    15961 tttaaagcgg atgtagaaag aataaaatag tttgtggagg taagtttagg tgatatataa
    16021 ctatggtttt ttagacgaaa acacaaaaaa agaaataaga agaaagatat taaaagcaat
    16081 atcaatacct ggttatcaag ttccctttgg ttcaagagag ttgcctatag ctaagggatg
    16141 gggtactgga ggtttacaat taacactatc attaattggt aaaaatgatg tagtaaaagt
    16201 aattgaccaa ggaagtgatg attctacaaa tgcttgtaat ataaggagct ttattgcaag
    16261 tgtaagtaat gtagaaacca caaaagatac attagaagct acattgattc aaacgagaca
    16321 tagaatacca gaagaaaaac ttaaatctaa tcaaatacta atatttcaag taccaatacc
    16381 agaaaccctt agaatagtag aacctagtga agtagaaaca agaagaatgc attcagaaga
    16441 agattatagt aggatgtggg tatatcttta tgaagatata gttagattta atgatatatc
    16501 tatagcagtt gaatatccat gtaaagtaaa tgatagatat ttaatgaatc catcacctat
    16561 acctagattt gatataaaaa aattaaatat gtcagacaat ttattcttgt ttggtgcagg
    16621 tagagaaaaa agaatttatg ctattcctcc atatacaaag gtagaacctt tagagtttga
    16681 ggattataag tttgaagagg aaaagtttga aggaaaatac tgtagtttat gtaacagtac
    16741 aaatacattt ttagatgaag tatatgacag tgacactaat gaaaagtact atagttgctc
    16801 agatacaagt tattgtgaaa aagttagatt aaaaaataac agtatagatg tgacaatagg
    16861 aggtacttgg aatgagtaaa ataaatgact ctaaaagatt agaaaatata gacaagcaag
    16921 tattaatagg aagaaatatc aatcttattt atggagatgg gtgtgaaaag tgttttgaaa
    16981 gcacaggata tgaaagcaat aatatatgta agtattgtgg ttctatagtt gcatgtaata
    17041 atgtaaattt agaactttat gaaggagaag tccttggaat tgtaggtgaa tctggttcag
    17101 gaaaaagcac tttattaaaa atactgtttt tccaagaaca tgcaaatagt ggagaagtat
    17161 atatatccca ttacaataaa gacacaaata tactagagct ttcagaccaa aaaaagagat
    17221 acataaagaa tcattttatg ggtattgtgt atcaaaatcc ccaccttggt ttaaatttag
    17281 actttagtag tggtggtaat atagcagaaa aattattgat ggcaaattta tataatgttg
    17341 aaaaaataag agatagaggc aaagaacttt taataaaaac taatatacct gtagaaagaa
    17401 tagaccataa accaaaatac tttagtgggg gaatgcaaca acgagttcaa atagcaaaag
    17461 ctctttcaaa taaccctcca atattgctat tagatgaggt tacaacaggt ttagatgttt
    17521 ctgtgcaagc ggaagtattg gatttaataa gagaaatcca aagagaactt aagatttcta
    17581 tgatagttgt atcccatgac tttgatgtta taaagatgct tgctgatagg acaattgtaa
    17641 tgaaaaatgg aagtgtgatt gagtctggtc ttacagacca aataatggag gacccgcaac
    17701 acccatatac tcagcaactt ataaattcat tgctataaat atcgtttgta aataagcaaa
    17761 atgggggttt ttaataaaat gaaagaaact atacttgaag taaataattt tagtaaagac
    17821 tttgagttac atgcattgaa caagactata acggcatgta gtaatataag ttttgaagtt
    17881 tcaaaaggtg agtttttagg aataataggt aaatctggag caggtaagtc taccatatta
    17941 aaaagtatct ataaaacata tataccaaca actggagaaa taatttttaa ttcagaaata
    18001 tatggtaatg tagacctggc taaaattgga gaccgagaaa tgataaatct tagaaagaaa
    18061 gaaataggat atgtatcaca gtttttaaag acacttccac gaataactgc aattgaactg
    18121 gtagtacatt ctttaattga gagtgggttt gaaaaagatt gttcgtatga tatggcaaaa
    18181 gatatactta accaatttga aataaaggaa aatttatggg atgcgtatcc aaataatttt
    18241 tctggtggag aaaaattaag attaaattta gctcaagcta tggttaaaaa gcctagactt
    18301 ttgttacttg atgaaccaac tgcatcactt gataatcaat ctaaaatata tgtaaaagaa
    18361 aaaatgttgg agcttaaaag tcaaggaact acaatgatag gaatttttca tgatatagag
    18421 tttatggaaa ctgttataga taagaccttt actatggcaa aagggactat aagtgaaagt
    18481 ggggtagcct agatgataaa actaattcat aatgcaaata ttgtattaga agatatgatt
    18541 ttagaaaatg gtcatttaat catagaggga gatacaataa aaaaagtatc aaatgataag
    18601 attgattacg catttgactt taatgagata gatgaaataa tagatgcaaa aaacttatat
    18661 gtaatacctg gtattataga tattcacagt gatgccattg aaaaggaaat agagccaaga
    18721 ccaagtacat tattaccatt taatatggca ttttatgaac tagataaaaa actacctgca
    18781 aatggaataa ctacagttta tcattctata tctttagggg atggagtagg agttagaagt
    18841 attgataact ctttaaagat gattaaaaat attgattcat ataaaaatat agatagtaag
    18901 agcataaatc ataaagttca tttaagatat gaagtgttgt attatgaagg tttagaaaag
    18961 gttttagaac tattagatga aaataaaata gactacttat caataatgga ccattctcca
    19021 ggacaaggtc agtatacaaa tccaacattt tataaagagt atgctactaa agtgtgggga
    19081 gttacagaaa attatgtaga tacatggtta gatgatttag taaatctgca tgataattta
    19141 gattggaata aaatagctaa tattataggt atagccaaaa ctaaaaatat aaatgttgca
    19201 tcacatgatg atgatacatt agaaaaaatg gatttcataa aaaatatagg cataaatgta
    19261 tctgaatttc ctataactct tgaagttgca aaacattcaa agaaattggg tgttttaact
    19321 tgtttaggtg caccgaatat tgtaagaggt aaatctcata ataacaattt aaaagcaatg
    19381 gatgctatat tggaagattg ttgtgacatt gtgtgttcgg attatcttcc atcagctatg
    19441 ataaagtcta tgtgtatagt tgcagaaaga ataaataatt taaataaagc agtcagttta
    19501 tttacctcaa atcctgctaa agcagttggt atatatgatg aaagaggtag tataaaagaa
    19561 aataaaaaag cagatttagt tttagtagat attgatagtg aatatccaaa ggttttaaat
    19621 actattgtaa atggaaaaac agtttataaa agggaggtat aaagattgct aacagagtta
    19681 cattgtcata caagtatatc agataataat tttactactg aagaaataat aaaaaaagca
    19741 gcagaaaaga atataaatat cttatcaata acaaatcatg acacattatc tggattggat
    19801 gaagctcttg tgcttggaga gcattatgga ataacaataa taccaggtat agaaatttca
    19861 gcctatgatt ataaaaatag aaaaagagtt catattcttg gatataacat agatttaaac
    19921 agtcaagaaa taaaaaattt gtgcaatcca atggtatgtg acagacataa agcatctgtt
    19981 aagatggtaa ataaaattat agatttagga tacaaaatat ctctggaaga tgtaaagaaa
    20041 tattcatcaa agactggaat atttaaacaa catataatga aagctcttat agataaaggg
    20101 tatacagata atatatattc aagtctatat aaagaattgt ttcatagagg aaacggcaag
    20161 gtatatgtat ctttaaaata tgtggattac agagatgcaa taaaagctat aaaaaattct
    20221 ggtggaattt gtgtgttagc tcacccgggt caaatggata attttagcgc tattgaagag
    20281 atggtaaaag taggattaga tggaatagaa gtatatcatc catctcacaa caaagaacta
    20341 gaaaaagagt cgctttctta tgctaagaag tataatctag tggtcacagg aggctcagat
    20401 taccacggat tttattctca acataattat gaacttggaa gcaagagctt aaataaagaa
    20461 gatttattta agtttaggtt agctttagga ggggtattat aaatgtcttt tttacaagta
    20521 aaaaatgtag gtaaaagtta tggacaagtt aaggtgttaa aagacatatc tattgatatt
    20581 gaaaaaggag agtttatttg tttactaggt ccaagtggtt gtggaaagag tacactactt
    20641 agaataattg cagggcttga ggataaacat ggtggaaaaa taataataaa tgataaggat
    20701 atgactaatt caccacctga aagtagaaat tttggtatag tttttcaatc atatgcatta
    20761 tttccaaata tgaatgttta caaaaacata gcctttggac tagaaaataa aaacataagt
    20821 aaatctaata ttgataaaaa agttaaagaa gttctagaag ttgtagaatt aagtggatat
    20881 gagaaaaaat atccatcaca attatcaggt ggacaacaac aaagggttgc attagctcgt
    20941 gcgattgctt tagagccaga ctttttactt cttgatgaac ctttatctgc attagatgca
    21001 aaagtaagac ttaaacttag ggagcagatt agaagtttac atagaaaact aggcattaca
    21061 actataatgg taacgcatga ccaagaagaa gctctttgtt tagctgataa gatggttgtt
    21121 atgaatagag gagaaataat acaagttgga acgccaaagg aggtatataa aaatccagaa
    21181 acaccttttg tagctgattt tataggaaca ataaatttta tagatgatgg tattaataag
    21241 atagctatta gaccagaaga tataaaagta gagtctaata gagattctaa agataaggat
    21301 ataaaagtgg gagaaatttt agatatcgaa tttagaggat ttaactatag aattacagtt
    21361 gagtatcgtt ctaagcaaat gaaattagat gtagtttcca aagttgcaga acaaatgaaa
    21421 ctgtgcatag gttctaaaat aaactttaag atacctaaag aaggaattgt acaatataaa
    21481 tcagagggat gtgcttaata gctaggggtg aataaatgat aacatcaaaa aataaaagaa
    21541 gaataagtga tagcacaata caaaaatatt tcttgatttt ttcggtaatt gtactaatag
    21601 tatttatatt atttccatta gtatcattat taaaaaatgc atttatggat acaagtggaa
    21661 attttatagg aatttcaaac tttagtaaat atgttgaaaa tccaagtctt atagcatcat
    21721 ttaaaaattc aatttttgta tctacagtct catctttaat atcactatgt ttagcattta
    21781 tatattcata cgcaataaca agaacaaaca taaagtttaa agattttttt aaaactatgg
    21841 gaatgtttcc actttttgca ccaactatgt tatatggtat ttcacttata tacctttttg
    21901 gaaataaggg aatctttaca accatgggtc tggaagtacc actatatggt ccattaggaa
    21961 taattatttc tcagattcta tttacatttc cacaagcttt tttaatatta tctgtagcac
    22021 tttcgatggc tgattataga ctttatgaag cagcagatag cttgggtgct agtgaattta
    22081 agaaattttg caaaataaca attcctggta taaagtactc attacttagt tcattctttg
    22141 tatcctttat acttgcattt acagattttg gagcagctaa ggtagtcgga ggaaactaca
    22201 atgtactggc tactgacata tataaacaag tagttggaca atttaacata ccaatgggag
    22261 ctactgtttc tatggtaatg ttaattcctg tactaatagc atttacatta gataagatgg
    22321 caagtaagaa acaaggtatg accataactg caaagtctat gccatataag attaaggaaa
    22381 ataagtttag agatagagta tttttaatag tatgtagttt tataacattg ctaattttta
    22441 ttttaatatt cgtttcagtt ataggttcag ttataaagtt atggccatat aatttaagct
    22501 ttacaatgga acactataca tttaaaggta ttttgggaag tggaataaaa acatacttaa
    22561 gcagtttgaa aatatcaact ttaacagcaa tatttggaac tatatttgta ttttttagtg
    22621 cttatatgat agaaaaggtg gataagtttc ctaaattaag acaaacagct taccttttat
    22681 caatgatacc aatggcctta cctggcttag ttttaggtat atcatatata acttttttta
    22741 actcagcaag taatccatta aattttttat atggaagtac agcaatatta gttatagtaa
    22801 atgtagttca tttttattca gtttgtttta taacctcaaa ttcatcttta aaaatgttgg
    22861 ataaagagta tgaattagtt gcaaaatcca taaatattcc attctataaa gtatttttta
    22921 atataacagt tccaatgtct ataacatcaa tacttgaaat agtagtatat tattttgtaa
    22981 attcaatggt tactgtttca gcattaatat ttttatatac acctcaaact cagactgcat
    23041 caatatcaat actaaagtta gatgagatag gatatatagg accatcagct gctatggcag
    23101 tattagtgct tttaacaaat ataatagtaa gacttttgta cgaatttgta acaaagaaat
    23161 taaaaaataa cacacaaaaa tggcagcaaa aagatgttgc ataggggagg taaaaatgaa
    23221 atttaagaag ctagtttctt taggagtatt atcaacactt ttattaagtg taataacagg
    23281 atgtagtact gattcatcag gttcagattc aaagtctgat agtaagacaa aaggggattt
    23341 aacagtttac acagcaattg aagaagatag tatagagcca tatttagcta catttaaaga
    23401 gaaatatcca gatattaaat taaatattgt tagggcatca acaggagata taacagcaag
    23461 attattagca gaaaaggata atcctcaagc agatgttgta tggggagttg cagccacaag
    23521 cttattggtt gcagatgacc aggggatgtt agaaccatat gctccaaaag gttctgaaga
    23581 aatagagtct gcatttaaag atgataaaga agttccttct tgggttggga tagatgcttg
    23641 gatgacaggt ataacagtaa acactaaaga attaagtgat aagaacatcc cagttcctag
    23701 ttcttacgaa gatttaataa agccagaata taaaggtctt atatctatgc ctaatccatc
    23761 ttcttctggt acagggtact taacagtatc agcccttata caaattatgg gtgaagaaaa
    23821 agcatggcag tatatggata aattgcatga gaatattggt gtatacactc aatctggttc
    23881 agctccagct acatcagcag cttcaggaga atatcctatt ggtatatctt ttggatatag
    23941 aggtataaag ttaaaagagg aaggctatcc agtagaagta gtatttccaa aagaaggttc
    24001 tggatgggat atagaagcaa atgctcttgt gaaaaaagat aatataaaag aagcatcaaa
    24061 agtattttta gattgggcta taagtaaaga tgcaatgaac gaatactcta agaactatgc
    24121 agttactact atttctacag gaaatccaat accagaagga ttccctaaaa agccattaga
    24181 gcaaatgata gataatgatt taaaatcagc agcaaaaaat agagaagata tactaaataa
    24241 atggatatca aaatatgatg gtaagacaga aaaagagagt taagtaaaac tatacaaatg
    24301 gagtaaaaag aaagaatttt tttaagtaga ttttattata ataatataag ttgagaataa
    24361 tataggtcaa gaaaagtgaa tattctataa aaatgtatag agtaagtata ccattcagtt
    24421 tgaatggtat attttttatt tttagagatt aatttagaaa tagatatact acagtttaaa
    24481 atagtatatt ttaatttcat tattaaagta tagatattat atataaagta aataaattat
    24541 tgagcgatta ttaataagat atgtataaat tttaatttgg gaacttgtgt tatatatcat
    24601 gaaaaaagag aaaaaataaa aggtaaattg tttcttgata acttgaaatt ggaagtgaga
    24661 atatttaact agagaagaat tatttaagtt taagtcagct ttaggaggag gaattataaa
    24721 tgtctttttt acaagtaaaa aatgtaggta aaagttatgg acaagttaag gtgctaaaag
    24781 acatatctat tgatattgaa aaaggggagt ttatttgctt attaggtcca agtggttgtg
    24841 gtaaaagtac attgcttaga ataattgcag gacttgagga taaacatgat ggaaaaataa
    24901 taataaatga taaggatatg actaactcac cacctgaaag tagaaacttt ggtattgttt
    24961 tccaatcgta tgcactattt ccaaatatga atgtatataa aaatatagcc tttggattag
    25021 aaaataaaaa tataagtaaa tctgatatag ataagaaggt tagagatatt ttagaagttg
    25081 tagaattaag tggatatgat aaaaaatatc catcacaatt atcaggtgga caacaacaaa
    25141 gggttgcact agctcgtgcg attgctttag agccagactt tttgcttctt gatgaacctt
    25201 tatctgcatt agatgcaaaa gtaagactta aacttaggga acagattaaa agtttacata
    25261 gaaaactagg catcacaact ataatggtaa cacatgacca agaggaagct ctttgtttag
    25321 ctgataaaat ggttgttatg aataatggag aggtaataca gattggaact cctaaagaag
    25381 tctataaaag tccaaaaaca ccttttgtag ctgattttat aggaacaata aattttatag
    25441 atgatgatgt gaatatgata gcaattagac cagaagatat aaaggtagaa tttaatagag
    25501 actttaaaga aattgatgta aaagtaggag agattttgga tatagaattt agaggattca
    25561 actatagaat tacagttgaa tattgttcta agcaaataaa gttggacgta gtttcaaagg
    25621 tagtggaaca aatgaaacta tgtgtaggtt ctaaaataaa cttcaagata cctaaagaaa
    25681 gaaccataca atataaatca gagggatgtg cttaatagct agaggtggat aaatgataac
    25741 aataaaaaat aaaagaagaa taagtgatag taagatacaa aaatgttttt tagttttttt
    25801 agtgattgca ttagtagtat ttatattatt tccattaata tcactattaa aaaatgcatt
    25861 tatggataca agtggaagtt ttgtaggaat ttcaaacttt agtaaatata ttgaaaatcc
    25921 cactcttata gcatcattta aaaactcaat ttttgtatct acaatttcat ccttaatatc
    25981 actatgttta gcgtttatat attcatatgc aataacaaga acgaatataa ggtttaaaaa
    26041 cttttttaaa actatgggca tatttccgct tttcgcacca gctatgctat atggtatttc
    26101 acttatatac ctttttggaa acaagggaat ctttacaatt ataggcatag aagtaccact
    26161 atatggtcca ttaggaataa ttatttgtca aatactgttt acatttccac aggccttttt
    26221 aatattatct gtagcacttt cgatggctga ttatagactt tatgaagcag cagatagctt
    26281 aggggctagt gaatttaaga agttcttcaa aataacaatt cctggtataa agtattcatt
    26341 agttagttcg ttctttgtat cttttatact tgcatttaca gattttggag cagcaaagat
    26401 agttggagga aactacaatg tattggctac tgacatatat aaacaagtgg taggtcaatt
    26461 taacatacca atgggagcta ctgtctctat ggtaatgtta attcctgtac taatagcatt
    26521 tacagtagat aagatagcaa gtaaaaagca agggatgact ataactgcaa agtctatgcc
    26581 atataagatt aaggaaaata agtttagaga tagagtattt ttaatagcat gtagttttat
    26641 aactttatta atctttattt tgatatttgt ttcagttata ggctcagtta taaaattatg
    26701 gccatatgat ttaagcttta caatggaaca ctatacgttt aaaggtatat caggaaatgg
    26761 aatcaaaaca tatttaagca gtttaaaaat atcaatttta acagcaatat ttggaactat
    26821 atttgtattt tttagtgctt atatgataga aaaagtggat aagtttccta gactgagaca
    26881 aatatcttat tttttatcaa tgataccaat ggcattacct ggtttggctt taggtatatc
    26941 gtatataact tttttcaatt cagcaagtaa tccattaaat tttttatatg gaagtacaac
    27001 aataatggtt atagccaata tagttcattt ttattcagtt tgctttataa cttcaaattc
    27061 atctttaaaa atgttggata gagagtatga attagttgca aaatctataa atattccatt
    27121 ttataaggtg tttttttatg taacacttcc aatgtccata acatcaatac ttgaagtggc
    27181 tgtatattac ttcgtaaatt caatggttac tgtttcagca ttaatatttt tatatatacc
    27241 tcaaactcaa actgcatcaa tatcgatact aaagttagaa gagatagggt atatagggcc
    27301 atcagctgct atggcagtat tagtgttttt aacaaatata atagtaaaac ttttgtatga
    27361 attgacaaca aagaaattaa aaactaagac acaaaaatgg caacaaaaag aagttgcata
    27421 gaggaggtaa aaatgaaatt taggaaatta gtctctttag gaatattatc aacactttta
    27481 ttgagtgtaa taactggatg taataatgct tcatcaggtt caaatttaaa gtctaataat
    27541 aagataaaag gagagttaac agtttataca gcaattgaag aagatagtat agatacatat
    27601 ttaactacat ttaaagagaa atatccagat attaaattga atgtacttag attatcagta
    27661 ggagatataa cagcaagatt attagcagaa aaagataatc ctaaagcaga tgtgttatgg
    27721 ggggttgcag ctacaagttt gataatttta gatgacaaag aaatgctaga gccatacgct
    27781 ccgaaaggct ttgataaggt aaatcctgta tttaaagatg ataagaaagt tccttcttgg
    27841 gttggaatag atgcttggat gactggtata acagtaaata ctaaagaatt aagtgataag
    27901 aacataccag ttcctagttc ttatgaagat ttaataaagc cagaatataa aggtcttata
    27961 tctatgccta atccagcttc ttctggaaca ggatatttaa cagtatcaga acttatacaa
    28021 attatgggtg aagaaaaagc atggcagtat atggataaat tgcataaaaa tattggtgta
    28081 tacactcagt ctggttcagc tccagctata ttagcagctt caggagaata tcccattggt
    28141 atatcttttg gaaatagagg tataaagtta aaaggtgaag gttatccagt agaagtagta
    28201 tttccaaaag aaggttctgg atgggagata gaatcaaatg cacttgtgaa aaaagataat
    28261 ataaaagaag catcaaaagt atttttagat tgggctataa gtaaagatgc aatgaatgag
    28321 tattctaaga attttgcagt tactacaatt gacacgggaa atccggtgcc agaaggattt
    28381 ccaaagaatc cattagaaca gatgatagat aatgatttaa aatcagcagc aagaaataga
    28441 gaggctatac taaataaatg gatagaaaaa tatgatggaa agacagaaaa agagagctaa
    28501 gccttgcaat aaaatttagt acaaaaagcg cctagaatat aagttttata tctaggctct
    28561 tttgatatat ttatttaaaa tgcatatttc tatataaaaa taaatagttt agtaccttga
    28621 ttaaattaaa taaaaacctt aaaataaaga gatgtaaaga aaaactaaaa acgaataaaa
    28681 ggtgaattta tatgataaaa gaaataatag tagtagaggg tagagatgac gttacagcag
    28741 ttaagagagc aatagatgca gaacttataa ctacaggtgg atttggattt ccaaaaggtg
    28801 taatggagcg tataaaagct gctaatgaaa gacgtggtgt tataatattt acagacccag
    28861 attttgcagg tgaaaaaata agaaaaaaaa tagcatcaga agttccagga tgtaaacatg
    28921 catttctacc gagagaggaa gctaaaaagg atggagatat aggtattgag aatgctactc
    28981 ctcaaagtat aatagcagct ctgaataaag ttagaactga aaatacagaa aaaagagatg
    29041 aatttaagca agttgactta attagaaatg gtcttatagg taatgaagaa gcatcactta
    29101 gaagagatgc acttggaaaa atacttggaa ttggatatgg aaatgcaaaa caatttttaa
    29161 atagattgaa taattatgga gttgaaagag aagaatttat agatgcatta aaacaaatct
    29221 aaacgtaata tttaatgtat gaaaaatatg tatataaaat aaattgtgga attacggtta
    29281 atttaagata aattatttat aatatatacc ttattttaaa tcaatgtaaa tacatataaa
    29341 taagtataat taataaaa
//
LOCUS       DAEPXW010000047        28882 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.048, whole genome shotgun sequence.
ACCESSION   DAEPXW010000047 DAEPXW010000000
VERSION     DAEPXW010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28882
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.048"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            40..504
                     /gene="bcp"
                     /locus_tag="KRM55_002073"
     CDS             40..504
                     /gene="bcp"
                     /locus_tag="KRM55_002073"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBH1594313.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            514..1257
                     /gene="yaaA"
                     /locus_tag="KRM55_002074"
     CDS             514..1257
                     /gene="yaaA"
                     /locus_tag="KRM55_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBH1594314.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFAIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            1385..4042
                     /locus_tag="KRM55_002075"
     CDS             1385..4042
                     /locus_tag="KRM55_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH1594315.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      4096..4198
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            4308..5573
                     /locus_tag="KRM55_002076"
     CDS             4308..5573
                     /locus_tag="KRM55_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBH1594316.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            5603..6493
                     /gene="metA"
                     /locus_tag="KRM55_002077"
     CDS             5603..6493
                     /gene="metA"
                     /locus_tag="KRM55_002077"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBH1594317.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            6984..7427
                     /locus_tag="KRM55_002078"
     CDS             6984..7427
                     /locus_tag="KRM55_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1594318.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKKGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            7458..9275
                     /gene="ftsH"
                     /locus_tag="KRM55_002079"
     CDS             7458..9275
                     /gene="ftsH"
                     /locus_tag="KRM55_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH1594319.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            9453..12155
                     /locus_tag="KRM55_002080"
     CDS             9453..12155
                     /locus_tag="KRM55_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBH1594320.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            12189..12887
                     /locus_tag="KRM55_002081"
     CDS             12189..12887
                     /locus_tag="KRM55_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594321.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            13244..14200
                     /locus_tag="KRM55_002082"
     CDS             13244..14200
                     /locus_tag="KRM55_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBH1594322.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            14377..14532
                     /locus_tag="KRM55_002083"
     CDS             14377..14532
                     /locus_tag="KRM55_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594323.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            14662..15675
                     /gene="aroF"
                     /locus_tag="KRM55_002084"
     CDS             14662..15675
                     /gene="aroF"
                     /locus_tag="KRM55_002084"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH1594324.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            15697..16761
                     /locus_tag="KRM55_002085"
     CDS             15697..16761
                     /locus_tag="KRM55_002085"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBH1594325.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            16761..18074
                     /gene="aroA"
                     /locus_tag="KRM55_002086"
     CDS             16761..18074
                     /gene="aroA"
                     /locus_tag="KRM55_002086"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBH1594326.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGKTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            18052..19131
                     /gene="aroC"
                     /locus_tag="KRM55_002087"
     CDS             18052..19131
                     /gene="aroC"
                     /locus_tag="KRM55_002087"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBH1594327.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDKIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            19134..20330
                     /gene="pheA"
                     /locus_tag="KRM55_002088"
     CDS             19134..20330
                     /gene="pheA"
                     /locus_tag="KRM55_002088"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBH1594328.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFGLDS
                     SNKNFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            20377..21186
                     /gene="aroE"
                     /locus_tag="KRM55_002089"
     CDS             20377..21186
                     /gene="aroE"
                     /locus_tag="KRM55_002089"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH1594329.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            21198..21731
                     /locus_tag="KRM55_002090"
     CDS             21198..21731
                     /locus_tag="KRM55_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBH1594330.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            21752..22591
                     /locus_tag="KRM55_002091"
     CDS             21752..22591
                     /locus_tag="KRM55_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBH1594331.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            22859..24340
                     /locus_tag="KRM55_002092"
     CDS             22859..24340
                     /locus_tag="KRM55_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1594332.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            24373..27810
                     /locus_tag="KRM55_002093"
     CDS             24373..27810
                     /locus_tag="KRM55_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH1594333.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTIELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDKKKALESIQHQLNTKGIAVYQHRIRRRNGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFINNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            27828..28574
                     /locus_tag="KRM55_002094"
     CDS             27828..28574
                     /locus_tag="KRM55_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBH1594334.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(28523..28831)
                     /locus_tag="KRM55_002095"
     CDS             complement(28523..28831)
                     /locus_tag="KRM55_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH1594335.1"
                     /translation="MNFFKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIVKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
BASE COUNT        11658 a         3046 c         5022 g         9156 t
ORIGIN      
        1 agtataaaat tattaataaa aacaaaagga gagatattta tgttgagtat aggaacaaaa
       61 gcaccagaat ttacactaga agataaagat ggaaataagg taagtatgtc agattttaaa
      121 ggcaaaaaag tagtagtata tttttatcct aaagataata caccaggatg tacacgtcaa
      181 gcttgtgctt ttagaaatgc atatgatggt tttaaaaagg aagatataca agttattggg
      241 ataagtaaag atagtataaa atcacatcaa aaatttgcag aaaagcatga acttcctttt
      301 attttacttt ctgaccctga cttagttgct ataaaagctt ttgatgtatg gaaagagaaa
      361 aaaatgtatg gaaaaactgc attgggagtt gtacgtgcga catatattat agatgaaaat
      421 ggaattattg aaaaagtctt tgaaaaagca aaaccagaca caaatgcaca agagattctt
      481 gaatatttgg aaaaacagga gtaataagaa tttatgatta taatgttatc accagctaaa
      541 aatatgaaga atatagaagt atttgataga gatttgagtt tgccttgttt tatagataac
      601 acaaaagaaa tagtggaaaa tataaagaca tttgctatag aagattttaa aaataaaatg
      661 aaaattaatg aaaaattagc tgtattaaat aaaaatagat ttgaaagcat taaatttgat
      721 agattaggaa accctgcaat cttaacttat gatggaatac aatataaaaa tatagaagca
      781 gaaaatttta caaggaaaga tgaagagttt gcaaatagct gtattcgaat cataagtgga
      841 ttgtatggtg ttgtaaaacc atatgatagt atatatgaat atagattaga aatgcagaca
      901 aaattacgag taggtgagtt taagaattta tacgaatatt ggggaaatcg tatatataaa
      961 gaactaatca aagaaaaaac agctatcgtt aatctttcat caaatgaata cagcaaatcc
     1021 atagaaaaat ttattaaaga tagtgataca tatattacat gtacttttaa agtaaataaa
     1081 aatggcatat tgaaagtaga atctacacaa gcaaagaaag ctagaggtat gatgacaaaa
     1141 tacattgtaa aaaataggat aagagatatt gaagaactga aaaagtttaa tttggaaggt
     1201 tataagtata aagaaaactt atctaacaat agtgaataca tatttgtaaa agagtagaag
     1261 ttttgttaaa tattaaatgg cattgttaaa tttaggtaaa atatacttag tgtgtattga
     1321 attgaacttg attttaaaat ataattattc ttaaattaaa aaaagaaagg agtggtcttc
     1381 caaaatggaa aatcacaaac agatgccttg gcattcaaga gcaacgcatg aaattttaga
     1441 aagtctagat tcatcagagg aggggctcac cgataccgag gcggaaaaac ggcttaaaga
     1501 gaatggttta aatgaactta gaaaaaaacc acctagaaca actttacaaa tgctttggag
     1561 tcaaattaca gatgctatgg ttatgatact aataggagca gcaatattat ctttgatatt
     1621 tggcgaattt acagaagctt ttgtaatact aataattgta acagtaaatg cagttattgg
     1681 aattgttcaa gagaaaaaag cagaatcatc attagaagca ttaaaaaata tgaactcacc
     1741 tacagctcgt gttatgcgtg atggtgaaga aaatgttatt ccagcaagta atcttgtagt
     1801 aggagatatt gtttttttag aagatggagc tatggttcca gcagaccttc gtttaataga
     1861 aacatcaagt ttaaaaattc aagaggcttc tttaacagga gaatctgttc catcagaaaa
     1921 agatgcagat acaatcttac ctaaagaatg tgtattagga gaccgtagca atatggcgta
     1981 tacatcttca atagtcacat atggtagagg tgtaggtgtt gtagtagcaa ctggtatgga
     2041 tacagaagtg ggtaacatag cacatctttt agattcacaa gatgattttg atactcctat
     2101 aaaacgtaaa cttaatactg ttggaaagac attaagtgtc ataggtatta ttgtatgcgt
     2161 tgttatattt gcaataggtg cattttatca gagacctctc ttgccaatgt ttatgattgc
     2221 aatttccctt gccatatcaa ttattccaga gggattacct gcaacagcta ctattgtaat
     2281 ggctttaggc gtacagcgta tggctaaaag aaatgcttta attagaaaat tacctgctgt
     2341 tgaaacatta ggaggagcta cagtaatatg ttgtgataaa actggtacgt taaccttaaa
     2401 taaaatgact gttacacata ttgctgtcaa tggagatttt gaatctggaa aagtgacatc
     2461 aatagatact gcatctgaaa aacatccatt agtgtataaa gagattgttt atgctggtgc
     2521 actttgtaat gatgcatgta ttaatccaga taaaacagat gaaatattag gtgacccaac
     2581 agagggcgca ttaattttta tggccaaaaa atttggaata gatcaagaag ctcttgaaga
     2641 agaatatcca cgtgtatttg aacagccttt tgattcagat agaaaatgta tgacaactgt
     2701 tcataatata gatgaaaaga ttattgctta tactaaagga gcagtagacg aaattcttga
     2761 cctatgtact aaaatattaa cttcaaaagg tgaaagaaac attactgaag tggataaaaa
     2821 gaatatacac gaattatgtc ttaacatgtc taaagatgca ttgcgtgtac ttggttttgc
     2881 taagcgtgag atttcatcta taccaaaaga agatagtgaa aatatagaat atgatttaac
     2941 atttataggt atggttggta tgattgaccc accaagaact gaggtaattg atgcagtaag
     3001 tacttgtaaa gaagcaggta taagaaccat aatgataaca ggtgaccata aagttactgc
     3061 cacaacaatc gctcatgagt taggaatatg gagtgaagaa aatactgtga tatctggtga
     3121 tgaacttgat aatttgagtg atgatgaact agatgaagct gttaaaaata ctacagtatt
     3181 tgctcgtgta tccccatttg ataaacttag aattatacaa tctctaaaaa gaattggaga
     3241 agtaccagca atgactgggg atggtgtaaa tgactctcct gccttaaagt ctgctgatat
     3301 tggtatagcc atgggtataa gtggtacaga tgttgcaaaa gattcttctg acatgatttt
     3361 aatggacgat agttttacaa caattgctta tgcaataaaa gaaggtagac gtgtatatag
     3421 aaacatacaa aaagttatac aatttttgct tgttggtaat atagcagaga tacttacgtt
     3481 gtttgtagca atattattaa attgggatac tccgcttctt gctgttcata ttctatgggt
     3541 aaaccttgca actgctacgc ttccagccct tgctcttgga gttgacccac caagcagaaa
     3601 tataatgaag caccagccag tgaaatcaac cactttgttt gaaaaaaatc ttatacaaag
     3661 agttgttacc caaggtatat ttgtggcaat aatgactatt ttagcatata aaattggtct
     3721 taatatagaa aatcattctg taggtcaaac aatggcattt tgtgtattag cattttcaca
     3781 gatgttacga gcatttagtc agcgttcaaa tacagattca atgtttaata gaaataatgg
     3841 taaaaatcca tttcttttaa tctcattttt aacttctgca tttttaatag cagtaatact
     3901 gtttgtacct gtttttagaa atgcttttaa cttaacagtt ttaaataact tagagtggct
     3961 tataacgatt gttttagcca taatgtctgt aattcaagta gaggttggga aaattattaa
     4021 aagaaaaaaa ttaaaaaaat agttgacaaa attaggaaaa atatataaga tataaaacat
     4081 agaaaaatta aataaatctt atccagagag gtggagggac tggccctatg aaacccggca
     4141 accagtatat ttatatacat tggtgctaaa tcctgcggcg aaagctgaga gatgagtata
     4201 attaagctta tacagagcct gagttatata ctcaggcttt atttatttta actctcatct
     4261 ggtaaatagt ttaatttttt ttactaaaat ctaaggggga tacaagaatg tataataaag
     4321 aaacaatatg tgtgcaagga aattataaac caggtaatgg agaaccaaga gtactacctt
     4381 tatatcaaag tacaactttt aaatatagca gtatagacca acttgctgaa ttatttgatt
     4441 taaaagttga tggacatata tattcaagaa taagcaatcc tactattcaa gcttttgaag
     4501 aaaaaataag tttactagag ggtggagtat cttctgtagc tgtatcatca gggcaatctg
     4561 caaatatgtt ggcagtttta aatatatgta aatcaggaga tagtatactt tgttcttcaa
     4621 aagtatatgg aggaacattc aatttactag gacctagtct taaaaaattt ggtatagatt
     4681 taatatcgtt tgacttagat tcaagtgaag atgagatagt agaacttgca aaggaaaata
     4741 ctaaggttgt gtttgcagaa acacttgcaa atccaactct tgaagtcata gattttgaaa
     4801 aaatagcaaa tgtagctaag agaattaatg ttccatttat tgttgataat tcattagcat
     4861 ctccagtgct ttgtaaccct ttaaagtatg gagcaaatat agttactcat tctaccacaa
     4921 aatatttaga tgggcatgct tcaagtgttg gaggaattat agtggatggt ggaaacttta
     4981 actgggataa tggaaaattt ccagaattag ttgagccaga cccaacatat catggtataa
     5041 gctatactca aaaatttgga aatgccgcat atgcaactaa agcaagagtt cagttgctta
     5101 gagactatgg aaattgttta agcccattca atgcgtatct tactaattta aatgttgaaa
     5161 cactacatct tagaatggag agacatagtg aaaatgcact taaaatagct agatttttag
     5221 aaaaacatga aaatgtagat tggattaatt acccaggact tgaagataac aagtattatg
     5281 agaatgccaa aaagtattta tcaagaggat gtagtggtgt tttatcattt ggagtaagag
     5341 gtgggttaga aaatgccaaa aaatttgtgg aaaaattaca gatagcatct ttggttacac
     5401 atgtttcaga tgtaagaact tgtgttatac atccagcttc aactactcat agacaattaa
     5461 cagaagaaca attaattgca tctggagtat tgccttcact aataagatta tctgttggaa
     5521 tagaaaatgt agaggattta atagctgatt taaatcaagc tttaaatttc taatattcta
     5581 agagaaagag aagtgaaaag atatggcttt aatactacca aagggattac ctgttattaa
     5641 taaattatta gatgaaggaa tagatgtaat ttataaagaa gattttaaaa aggaattaaa
     5701 gtatgaagaa aacatagaca ctaagatagc tatactaaat ctaatgccta taaagataga
     5761 tacagaatta gatttactaa gaaggataga taaaacagga ttcaacgtgt ctgtggaatt
     5821 tattaaaatt tcaacaagag aaagtaaaag aagttgtaat gaatatgtta aagaatttta
     5881 taaaacattt gatgaagcca aaggagagta ttttgatggc tttataataa caggagctcc
     5941 agttgaacaa atggagtttg aagaagttga ttattggaat gaactagaag aaattatgga
     6001 ttattctaag agaaaaacta aatctacatt atatatatgt tgggcagctc aagcaagtct
     6061 ttacaaatac tacaatgtaa aaaaacttcc actaagtcaa aaatgttttg gagtatttaa
     6121 gcataaggta gataaagata gtaaaatagt agatggattt gaaaatgaat tttttgctcc
     6181 acattcaaga catactactg taaatattga agctttgaaa gagaataaag agttgagcat
     6241 tgtgagtcat tctaaagaag ctggtcccta tataattaca aattcaagag atgtgttcgt
     6301 aatgggtcat agcgagtatg acaaatacac tcttgataaa gaatataaga gggatataaa
     6361 taaaggagat aaaatatcta tacctcaaaa ttactatatt aatgatgacc cttcagaaga
     6421 gccaactgta aaatggaaaa aacattcaga attgttgttt agaaattgga taaaaaacta
     6481 tttgatacaa taaattttaa gagtatataa atgttaacta aaaaaatata gaaatttata
     6541 ggtataaagt taatcttaat gatactttat accttatttt tttaaaattt gaccttataa
     6601 tagtagtttt atattttaag aaaatcactt taggtgtatg tagatagagg tggctttaat
     6661 tttatatatg gtgcgataat gggagactaa acctttatag tatcaataaa tttgtatttt
     6721 aacttttaaa agagattaaa aagggagaaa tcagtgtaaa atatatatat agatttttta
     6781 ttaaatttta ttaaaaatat cctgtataaa attaaatatc aataagataa caaaatttca
     6841 attgaagtta caatattgta attgacaata aatacttaat actataatat ttaatacatt
     6901 aaacattata gtgttaagta tttatttaca gtatgcactt cagcctaaat ttgaaataaa
     6961 gtattttcgt agggagcgtt tgtatggatg agatgagttt taagaaagag ctactagagt
     7021 tgactagaga tataaatatg aaatttacaa ctttattaag tgatttttat cagccacttg
     7081 gtattacagc agtgcaagct ttgattttat ctgagttatg tgaacatgga gagaaaaaaa
     7141 taagcgattt agggaagaac ttaaacatga caaatagtaa tgtatcagta atctgtcaaa
     7201 ggcttgaaaa aaaaggcttt ttaaatcgca taagagatat agaagaccaa cgaattgtaa
     7261 aagtaaaagt tacaaataaa tcattggata tacaagaaca tatttcaagt agtatttttg
     7321 atagttattt tgaaaatatg accagtgaaa aattgcaaga tatggaagat ataatagaag
     7381 gtttagagaa attaaataaa cttttaactt acattgattg caaataacat aaaaataatt
     7441 taaaggagaa taaaattatg gatgaacata aaccccaaaa aaggtcagca ctctattatt
     7501 atacagttat aataatagta gtaatgtttt taaatgcttt aatatttcca agtttaatgg
     7561 ataaaaaaat ggttgagatt gactatggaa agtttctcac aatgttggat acaggaaagg
     7621 ttaaatctgt tgagatagaa aataatagaa tagcaataaa tccatctagt agcaaggata
     7681 agaatatata cataactggt agaatggatg acccagaatt ggtagataga ctaaaaaatg
     7741 caaaagtaga atttactaag gttattccta aggaaaattc acctctttta agtattttac
     7801 ttacatggat aatacctata ggtattctta tgctatttgg taacttaatg atgaagtcta
     7861 tgcaaaagcg aatgggtggt aatgctatgc aatttggaaa aagcaacgcc aaaatgtatg
     7921 tatctgctca aagtggaaaa agatttaatg atgtagctgg tcaagatgag gcaaaagaag
     7981 ctttaactga aatagtagat ttcttacaca atccagaaaa gtataaaaag ataggagcac
     8041 aaatgcctaa aggagcactt ttagtaggac ctccaggtac aggaaaaaca ctccttgcaa
     8101 aagctgtagc aggtgaagca aatgtaccat ttttctcaat atctggttct gagtttgttg
     8161 agatgtttgt aggaatggga gcttctagga ttcgtgattt atttaaacaa gcaaaagaaa
     8221 aagctccatg tatagtgttt atagatgaga ttgatactat tggtaaaaag cgtgataatg
     8281 gaagtggatt aggtggaaat gatgaacgtg aacaaacttt aaatcagttg ttaagtgaga
     8341 tggatggttt tgatggtgga attggagtag taatacttgc tgctacaaat agacctgaca
     8401 gtcttgacaa agcattactt cgtccaggaa gatttgatag acgtatacca gttgaacttc
     8461 cagaccttgg aggacgtgaa gctatattaa aggtacatgc tcaaaatgta aatgtaagct
     8521 cagatataga ttataatgca attgcaaggt ctacatcagg agcatcaggt gcagaacttg
     8581 caaatattgt aaacgaagca gcacttttag cagttaagtc tggcagagat atagtagaac
     8641 aacaggattt tgatgaatct gttgaaactg taattgctgg gtatcaacgt aaaggagctg
     8701 taatttcaga taaggaaaag aaaattatag catatcatga aataggtcat gcacttgttg
     8761 ctgctatgca aaaacattct gcacctgtcc ataagattac tataatacct agaacttcag
     8821 gagcattggg atatactatg caagttgctg aagatgagag tgtacttatg tctaaagaag
     8881 aagcaattga taaaataact acttttacag gtggtcgtgc tgctgaagag gttatcttta
     8941 acacttgtac atcaggagca tcaaatgata tagaacaagc tactaaaatt gcaagagcta
     9001 tggttactcg ccttggtatg agtgaagagt ttgatatggt cgctcttgaa actgtaagca
     9061 atcaatattt aggaggagat acttctcttg cttgttcttc cgacactgct gctaaaatag
     9121 atgaagaggt atttaaaata gtaaaggctt gtcacaaaaa tgcaattgaa atcttagaaa
     9181 ataatattga taaattgcat gaacttgcta attatttatt agaaaaagaa actattacag
     9241 gtgatgagtt tatggaaata cttaacttaa actaaaatga ttatacacaa gataaaaatg
     9301 cctattgtta ggcattttta ttttacaact aaatttttta aattcatatt taaatcttta
     9361 cataatctta atcattaaaa atacatctta actacaattt tatatcggaa ttgatattat
     9421 aatagtaatg aatggtgtaa ggaggttttt taatggatag acctaatcct gatattctat
     9481 tagaaaaaat taaaaatgaa gaagaaaaac taagtagagg tcaattaaaa atattctttg
     9541 gttatgcagc tggagtagga aaaacctact ctatgttgga atctgcacaa aatttaaaaa
     9601 aagtgggtgt agatgtagta gttggatata ttgaaccaca cactagacca gaaacattgg
     9661 ctttacttga tggcttggaa attcttcctg taaaggagat agaatataaa tctataaaac
     9721 taaaagaatt tgatttagat gctgctttag caagaaaacc agaagttata ttagtagatg
     9781 aatttgccca ttctaatgtt gctgggttaa ggcatacaaa aagatggcaa gatatagaag
     9841 aattgctgtt agcaggcata aatgtctaca ctactgtaaa tgtacaacat ttagaaagtc
     9901 taaatgacat tgttgagata attacaaacg tatcagttaa agagactata ccagataagt
     9961 ttttggatac aaatacacag ttagaactta tagatgttga acctgatgta cttcttgaaa
    10021 ggttcaatga aggtaagata tataagaaag aacaagctac tagagcaaaa aataattttt
    10081 ttataaaaga taacctggtt gcacttagag aaatcgcact tagaaaaact gcagagagag
    10141 ttaataaaga agttcaaatg accagactat caaagggtga tgtaactgta atacctacat
    10201 cagatacact tcttgcatgt ataagtccat ctccatcttc agcaaaagtt attagaactg
    10261 catccagaat atcagacagt acatttgcaa aatggatagc tttatatgtt gaaactccaa
    10321 acacagcaag acttccattt gatgaacaaa aacaactaca aaataaccta aaattagcta
    10381 agaaattagg tggagaaata attgttttac atggtgaaaa tataatagag caaatactta
    10441 gaattgcaaa gctgagaaat gtaacaaaaa ttgtaatagg tagaaatcat tcaagtaata
    10501 aaagatttag taaaagattt aaaaaagata tagttgacaa attaattgat gaagttgatt
    10561 atatagatat acatataatt ccatataaat ttgcctcaga tgttaaatac aaacctaaaa
    10621 aggataaatc atcaataaaa tctaaattta aaattagcaa agttgatttt ataaaactta
    10681 tatttattac tttgatgata agtattttag catatgcagt acaaagcatg ggatttataa
    10741 gagaaaatat attgttaata tatatgttgg gtgtagtttt agtttctatg tggactaaag
    10801 ggtatagtac aggtataata agttctgtat ttaatatagt tcttttaaat tattttttca
    10861 cagcaccatt atatacatta tctatagcag attcaaacta tatagtaaca ctggttgtat
    10921 tctcaatagt aggtataata actagcactc ttacgtctaa gatacagcat gaagcagaaa
    10981 ctgctgctaa aagagaagaa aatacaaaaa tgatatatca aataattaag ggatttttaa
    11041 gattatcaaa taaagatgat atagtaaaca aaggtataga acttttgtct cttagcttaa
    11101 gtagagatgt aatttgttat ttaaatgtag ataagcataa taaatcaaag ctttacaaaa
    11161 aaaatactaa taataaggat aaaaatgatt tggatagtga agatgaaaaa gctgttgcaa
    11221 gttgggtttt atccaattca acagtagcag gaaatgacac ggatacactt cctggttcaa
    11281 agggatacta tataccaatt gtaggaatga atttaacttt aggagtagtg ggaatatcat
    11341 gtattgattc aaaattggat acagaagata taagcttaat tgaaacaata attgctcaaa
    11401 tggcaatagc gcttgataga gaaatcttgt cagaagctaa agaaaatacc aatcttgaga
    11461 ttgaaaggga aagattaaga agtaatcttt taagagcagt ttcgcatgac cttagaactc
    11521 cactagcagg aatatctggt gcagtaagta caattataaa aaacaagggt actataggtc
    11581 aagatataat agatgaatta cttagtggtg tatatgaaga tactcagtgg ttaataagac
    11641 ttgttgaaaa tttacttagt atgaccaaga tagatgaagg gaaattggaa gttaaaaaac
    11701 attctgaact ggttgaggaa attatatcag aagcgttaca aaaaataaaa aaaagaattg
    11761 aaaatgcact tatagatatt aatataccag aacagatatt atttgttcct atggatgcaa
    11821 aattaataga acaagtttta attaatttaa tagataattc tttgaaatat tcaaaggaag
    11881 attgtaagat agagataaat gtatatgaga aagatgatta tgtttggttt gaagtatctg
    11941 ataatggtcc tggtatatca aaggaactta aaaagcatat ctttgacaga ttttttactg
    12001 gagaagaagg agctaaagat tccagaaagg gtgttggact tggattatca atttgtaaat
    12061 ctataattca agctcataaa ggtgaaatta tggtagaaaa caataaagat aagggttcaa
    12121 cttttaagtt tagtttgcct aaggaaaatg aatagtttta aattttaaaa ttagttttgg
    12181 aggaagaaat gagtaaaaaa cttatattgt tagtagagga tgataagaca ataagaaaat
    12241 ttatatctac tgcactttta acacaggatt atgatgtcaa ggaggctata actggaaaag
    12301 aaggtatctc tattgctgtc tcatattctc cagatgttgt tcttttagat ttaggcttag
    12361 aggatatgga tggaatagag gtaataaaag ctatcagaca attttcaaat ataccaataa
    12421 ttgtagtttc agctagagag caagatagag acaaggtaga agtatttgat gcaggggcag
    12481 atgattactt aacaaaacca ttctccatag tagagttatt agcaagagta agagtagcat
    12541 ttagacattc acaagtagaa gctcaacaaa aagatgatgt taaatctacg tttgaagtag
    12601 ataaattatt gattgatttt gataaaagaa aagttattgt tgatgatgtt gaagtccatt
    12661 tgacacctat tgaatataat attctttcat tacttgcaaa gcatcatgga aaagtgctta
    12721 ctcataattt tataataaaa gaaatatggg gtagtgttat agggaatgag actaagtctt
    12781 taagggtctt tatggcaacg ttaagacgaa aaatagaaaa acaacctgca aacccaagat
    12841 atataattac agaagttggt gtaggataca gattaaatga tgaatagttg taatatatta
    12901 attattagat tatgtgctta ttaatatata ttaaaattat atagtttagt taaaataaga
    12961 atgaagtgta tgtgcttgtt gtcagtttag cacatgcatt ttatttttta gcttttttag
    13021 tatcaataat tttttagtat caataatatg aaatatgttt taaaataagt atatagtgta
    13081 atctgtaata aaaactttgg ttaaataata aatgtattta acacttacct tataataaat
    13141 ttaatataaa tattaaataa taattattaa aatagtgtaa aataattaca gtaatgatta
    13201 taaaaaaatt ttagaatgta aattgaaatt taggagtaga tgtatgtata tactgaattt
    13261 aaatacaaga gagactattg aagattttag agataaattt tatgtagcag aaaattctta
    13321 tcttatatta agtgctccaa aaaatttaaa attgcttaag gaaactttgg atatagatga
    13381 aataactttt aatgattgtc ttaaatttga tgaaataacc aaacttgatt tatttgataa
    13441 ttacgatttt ttaagcctaa atacatttga actaagagat ggagaagctg ttatagaaga
    13501 ggtaaatatg tatttatcag ataattttat attggttgta gtgaatgaag aacacttttt
    13561 atttgaattt gtaaaaaata ttattttgaa gaactctcaa cttgaaaaaa atccagttat
    13621 taatctattt aagataaact acttgattct tagagaagtt ataaaaaatg gttttgagtc
    13681 tttggaaaaa gttgaagagt taattcttca aatagaagat gaaatgatgg acaacattaa
    13741 taagaatcat gtatctagaa taagtgatgt aagaggatta acaagaatta tagttaagaa
    13801 tactagacct cttttgtata ttggggatag aatagttaag gaaaatataa gatatttaaa
    13861 atattcaaat gtaaaaaaat ataatttaga aaattttcaa ggcatagatt ttggaattga
    13921 caaattatac aatttcgcat tgtcaacacg agagttagca gataaattat tagatattta
    13981 ttcttccaga gtaggtgaga aaacaaataa cttaattaca aaattaacct tgttaacagc
    14041 catatcagca ccacttacaa ttataactgg tatatatgga atgaacttta gatatatgcc
    14101 agaattaaac tggatttatg gatatccagc aactttattt tttatgctat gtataatttt
    14161 tgttggaatt ataatattta aaataaaaaa attattgtaa attacagatg atgtttaatt
    14221 gattttataa aaatacatca attgagaagc tgatttaagt aaataaaaaa atattttaaa
    14281 ttgaaaatat ttatagaaaa tattgacaat tatattttct ttgttataat tattaaacaa
    14341 gaagaataat aaattataaa aatggaggat aatactatga aaggaatatt aaaagaacta
    14401 acagcaaaac tttatagctt tttttacttt atgttctggg gcttttattt tagcgctggc
    14461 tatttctttt acaaaaatat atgtacttcc tttctggtga ggccttattt tagtgatttt
    14521 gagcataagt aaattttata aaaatgatta ttttatatat ttatataaga tttagtgctt
    14581 gatagattat tttagagaac tcattagtga gttctctttt ttattttaaa tataaaatta
    14641 taatattggg aggtagtaaa aatgatagta gtattaaaaa tgggagcaga taaaaatgaa
    14701 gttaaaaaat taattgaggc tattgggaga gaaggagtag aagttaatcc catagatgga
    14761 acagaattaa ctgttttagg tttagttgga gatactagta aaatagatgc caaaagaata
    14821 gaagcaaata aggtagttga aaaagttatg catgtggtag agccttttaa aaaggccaat
    14881 agaaaatttc atccagaacc ttcaatcata aatgttaatg gaatggaaat tggttcaaag
    14941 aaaattgcta tgatagctgg gccttgttct gttgaaacag aagaccaaat agtatctata
    15001 gctaaagatg tgaaaaaatc aggtgcagga tttttgagag gtggagcatt caaaccaaga
    15061 acatcaccat acgctttcca aggattgaaa tatgatggat tggatttatt aaaaaaagca
    15121 aaagaaaaaa cagggcttcc tatagttaca gaaataatgt caacacaaga tatagatata
    15181 tttgaagaaa atgtagatgt aattcaagtt ggagctagaa acatgcaaaa ctttgattta
    15241 ttaaaagaat taggtaaaac aaataaaaca atacttttaa aaagaggatt atctgctaca
    15301 attgaagagt ggctaatgtc agcagagtat ataatggctg gaggaaatga aaatgtagtt
    15361 ctttgtgaaa gaggtataag aacttttgaa acatatacta gaaatacttt ggatttaagt
    15421 gcaattttag ctgtgaagaa acttagtcat ttaccagtta tagttgaccc aagtcatgca
    15481 gcaggtaaat catggatggt tgactcttta tctaaggcag caattgcagt tggagcagat
    15541 ggtctaataa tcgaagttca taatgaccca gcacatgcac tttgtgatgg aaaacaatcg
    15601 attaagccaa atgaatatga tgaattgata agtgaattaa agactatcgc atcagcagtt
    15661 ggtagagaaa tataatctat aaaaggatgg ttaaacgtgg aagaaaaact attagtaaat
    15721 ttaaaagaaa atagctacaa tatatttatt aaaaaaaata tactaaagaa tataggagaa
    15781 gaaataaaaa aaatatattt tggaaataag atttttattg taactgatga aaatatagca
    15841 aaattatact tggataaagt aaaaaataat ttaagtgaat ctggatttga aattaaatct
    15901 ttaatattaa aatctggtga agaaacaaaa tcatttaata ctcttcctaa aatatacgat
    15961 agtttacttg actttaagtt aactagaaaa gatttgatta ttactttagg aggaggggta
    16021 ataggtgatt taggtggatt tgcagcagca acttttttaa gaggtataag ttttattcaa
    16081 attccaacat ctttattagc acaagttgat agttctgtag gtggaaaagt tggagttgac
    16141 cttgagagag gcaaaaactt agtgggaagc ttttaccaac caaaggctgt gtttatcgac
    16201 ccaaatgtat tattatcact tccagaaaaa ttctatagag atggaatggc agaagttata
    16261 aaatatggat gtataaaaga caaaactttt ttcaataaac ttttaagttt aaaaaataga
    16321 gaagaagtaa tgcaacatat agaatacatt atacataaat gttgctttat taaaaaaact
    16381 gtagttgaag ctgatgaaaa agactttgga gatagaatgc ttctaaactt tggccataca
    16441 ttaggtcatg ctattgagaa atactacaat tttacgggtt atacccatgg agaagctgtt
    16501 gccataggaa tgtataagat aactttagaa agtgaaaaga taggaattac aaaaaaaggg
    16561 acatcagaac ttataaaatc aattttaatg aattataatt tgccttatga gattgaatta
    16621 agagataata aatctatagt agatgctata tctcttgata aaaaaaatct aggtgataca
    16681 ttaaaaataa tacttttaaa agatattgga gagagtatta tatataatac tacttctaaa
    16741 ttttttcagg aggtaagata atgggaagtc taaaaatata tccaagtaaa ttatctggag
    16801 atgtaaaaat accaccatca aaaagtatgg cacatagggc agttatttgt tcatctctaa
    16861 gcaatggaaa aagtagaatt tctaatatag atttttctga tgatataata gctactataa
    16921 gagcaatgac atcattagga gctattatag aaaagaaaga agatatttta gaaatttcgg
    16981 gaattttttc taaagaaggt attttaaata gagagaatca gttgaatcaa cctaaattga
    17041 caatagattg taatgaatca ggctctacat tgagattttt agtacctata tctttagcat
    17101 ttgatggtgt aaaaaggttt ataggtagag gaaatcttgg aaaaagacca cttgatactt
    17161 attatgagat atttgacaga cagaatataa aatatagtta caaagaaaat cagttagatt
    17221 tgattatatc aggtaagctt aaaccagatg aatttagagt aaaaggaaat ataagttctc
    17281 agtttatcac aggtttactg tttatattgc ctacgctaga gagtgattca aagataataa
    17341 ttactactga gctagaatct aaaggatatt tagatttaac tctttcaacg ataaaagatt
    17401 ttggggtaga aattataaac aataactata aagaatttat tataaaagga aatcaaacgt
    17461 ataaagcgag agattataaa gtagaaggag attattctca aggagcattt tatttatcag
    17521 cagatgctat aggagaagat attagcatat tagaccttaa agaagattct cttcaagggg
    17581 atagtgaagt agttgaaatt ttatctagga tgggaatgga aatattaaga gaaggcaaca
    17641 aaataaaagg aataacaaat ggtttaaatg gtactttgat agatgcatct caatgcccag
    17701 atataatacc tgtattatct gtagtagcat ccttaagtat agggaagact acaataatta
    17761 atgctggtag gcttagaatt aaagaatgtg atagacttca tgcaataaat gttgagttaa
    17821 gtaaacttgg agcaaatata gaggagaaag aggatagttt gataatcgaa ggagtaagca
    17881 agttaaatgg tggagtagag gtgtggagtc acaaagacca tagaattgct atgacacttg
    17941 caattgcttc ttgtagatgt gataaaccaa taatattaaa agattttgag tgtgtatcaa
    18001 aatcttatcc acattttttt aaagatttta agatgttagg aggtcgaatt gatgagtgga
    18061 atatggggaa ataatttaaa agtatcaatt tttggagaat ctcatggaaa tgctataggt
    18121 ataaatatag atggtcttcc ttcggggatt gaacttgacc ttgataagat tgataaagaa
    18181 atgaagagaa gagcacctgg aaaaaattct atatctactt caagaaatga aagtgatata
    18241 ccagaaattc taagtggata ttttaatgga agaactacag gaacgccatt atgtgcaatc
    18301 ataagaaata gtgatactcg ttcaaaagat tatggagagc ttaaaaattt aatgagacca
    18361 ggacatgcag atttcacagg taatgtgaga tattctggat ttaatgacta tagagggggg
    18421 gggcattttt caggtaggat aacagctcca ttagtatttt gtggggctat atgtaaacaa
    18481 attttatcac aaaaaggaat agagatagga gcacacataa aaaaaattaa aaatatagaa
    18541 gatatgagtt ttgattatgt aaatatttca aaacaacagt tatcaaattt gcaaactttg
    18601 gaactacctt tacttgattt atcaaaggaa gaagccatga aaaatacgat tatagatgca
    18661 aaaaatcaag gagattcagt tggtggtata attgagtgtg cagtagtagg tattaatgta
    18721 gggcttggga atccattttt tgactctgtt gaatctactt tatcacattt attgttttct
    18781 gttcctgccg taaaaggtgt agagtttggt ttaggttttg aacttgcaga tatgtatggc
    18841 tctcaaagta atgatgaaat gtattatgaa ggaaatcaag ttaagagcaa aacaaataac
    18901 aatggaggaa ttataggagg gattactact ggaatgccaa taattttcaa agtggcaatt
    18961 aagccaactc catcaattag cagacaacaa aacacagtta atataaaaga taaaaaggac
    19021 gatattttat atattaaagg cagacatgac ccttgtatag ttcaaagggc tatacctgta
    19081 atagaagcag taacagccat tggaattttt gatttgatga aaggacgata ataatggagg
    19141 atttaacgag atatagaaat gagattgaca atatagataa agagcttatt caattatttg
    19201 aaaagagaat gaatacagtt cttgaaattg ccagacataa aatgaaaaat aatactacta
    19261 tacttcaaaa agatagagaa gaaaaagtac taagtagagc tgtagataat ttagataata
    19321 aagcatattc acaagaaacg gtacagtttt ttaattctat aatggaaatt agtagaggat
    19381 tacaaaaaag attgatagat aatgatggtg agcagaaaat cgagtttggt ttagattcat
    19441 caaataagaa ttttgatttg tcaaatgtaa ataaatataa gtctttaaaa gatgaattaa
    19501 ataaaaaaaa tatcctagta gggtttcctg gaaaatcagg ttcatttaca gaagaagcac
    19561 taaataaatt cttcaacaaa aaaatatcaa aaaaacaatt taaagaattt gaagatgttt
    19621 tcatagcact taaaaataaa gaaataaact atggaataat ccccatagaa aattcatcta
    19681 caggagctat ctctgaaact tatgaccttt tgagaaagta cggtttttat atagttggag
    19741 aagaatgtat aaaaatagac caaaatttaa tagggataaa agacacaaag cttgaagata
    19801 taaaagaaat atattctcat ccacaaggta taggacaatg tagtgaattt ttaaaacaaa
    19861 atagtacatg gaaattgata ccatttaata acacagcaac aagtgcagaa cttgtaagaa
    19921 aacttcaaga taaaacaaaa gcagcaattg caagcaaaaa agctgcaagt atttatggat
    19981 tagaaataat aagtccttgt ataaatgata tagcaaacaa ctatacaaga tttgtagtaa
    20041 tcagtaatca aatacacatt gaagaagaat caaacaaaat gagtgtagta ttttctgttg
    20101 aacatgaagc aggaaaactt tataaagtac ttggatactt tgctaaaaat aatataaata
    20161 tgacaaaaat agaatcaaga cctatgaaaa atgcctcatg gagatatttc ttttatatag
    20221 attttgagtg ttctatatac aatgctaaag tgtacgattt attagaattg atagaacata
    20281 atacagcata ttttaaattt atgggagtat ataaaaataa aactgaatag ataagataaa
    20341 tttttattta atttataatt attaggaggt gtaagtatga attttttcgg tctagtaggt
    20401 gaaaaactct ctcacagtgt ttcacctcaa atccacaaga gagtattcga gatattgaat
    20461 attgaaagtg cttataaaaa ctttgaaatt tcaaaagaag atatatctaa gctagacggt
    20521 gctataaaat tattaggaat acaaggggta aatgttactg taccatataa ggagcgtatt
    20581 atgaaatatc ttgattttat atcaccagag gcaaaacgta taggagcagt taatacaatt
    20641 ttacttagag aaaatatgtt atatggttac aatacagatt actttggtct tgatagtatg
    20701 tttaaaatgg ctaatattga tgttcaagga aaagtagcag ttatattagg aactggaggt
    20761 gcttctaaag ctgctcttac atattttatt gattctggta tagaaaagct ttatgtttca
    20821 actagaaaaa aggatgataa aaaattatta aatagtaaag ctatattaat agattatgaa
    20881 gaacttaaac atataaaagg agatataata ttaaatgcta caccagtagg tatgtaccct
    20941 aatgtaggaa tttcaccagt gtcaaaatct attatacaaa attttgatat attaatagat
    21001 ttaatttaca atcctggaga aacagagttt ttaagaattg gtaatagtat gggtaaaaaa
    21061 acttgtgatg gattatatat gctggtgggg caagcaataa aatctcagga aatttggcaa
    21121 gatactaaaa tagataatag tattttagat gttatatata atgaactaaa attagaattt
    21181 ttgtaaggga gattgttatg ataaataaaa caaaagaaaa attgatatta ataggtatgc
    21241 caggtagtgg aaaaactaca attggtaaac ttttggccaa agaatataat tgtagtttct
    21301 gtgatatgga tgattatata attcaaatat ctcaaaaaag tatagcagag ttgttttcag
    21361 aaggagaaga tatctttagg aactatgaga ctcaagcatg tagagaactt tctataagtg
    21421 ataaaacagt gatatctaca ggtggaggtg taataaaaaa ggatgttaat atggaaatac
    21481 taaaagaaac aggtataata atttttattg atagacctat acaaaagatt ttggaagata
    21541 taaatattaa ttcaagacca ttattaaaaa acggaaaaga tagattgtat aatctttaca
    21601 atgagagaat aaatctttat aaaaaatttt cagatataga gattttaaat gataaatcat
    21661 taaataatgc tgtatataat attacaaatg cagtcagtga aaattttaaa tttgacttta
    21721 aagaaaaata atctaggggg aagtaaaaat aatgaatatt gttattgtag gactaggagt
    21781 tataggaggc tcttttgcta aagcattaaa aaaagctgga tatgaaaatg tatttggagt
    21841 agatgtagat ttagaaactt taaaaaaagc agaaaaagca aaaatcataa aaaaaggatg
    21901 tactacaggt aaagagttat ttaaaaaagc tgatttaatt atactatcta tatatcctag
    21961 attagttgta gattttctaa ataataataa aaactttttt aaaaaaggga ctataattac
    22021 tgatactaca ggaataaaag aaacacttat caatgatgtg ttgcaaatta ttccagatga
    22081 tatagatttt atatttggac atccaatggc aggtagggaa aaaaagggta ttgattttgc
    22141 aagtgaacaa gtttttaatg gtgcaaatta tataattact ccaactggca gaaacaacat
    22201 aaaaaattta gagttagttg aaaatttaat tttagagatt ggatttaaaa gagtaaaaaa
    22261 gttaacttca caaaaacatg atgagattat agcttttact tctcagttac ctcatgttat
    22321 ggcagttgct cttataaata gtgatgaaga aggtagagat acgggtaaat ttattggaga
    22381 tagttataga gatttaacta gaattgcaaa tatgaatgaa gacctatgga gtgaactttt
    22441 tttaggaaat agagataatt tactaaaagt tatagaaaac tttgaatcag aagtaaattt
    22501 agtaaaagaa gctatattta acaatgataa aaataaatta atagagtatt ttaaaaaatc
    22561 atcaataaga agagaagctt tagaaaaata aatattaata tttaagctat atatagatgg
    22621 gtataaatat aagcgatagt gtatttaatt gtattaataa atatggattc aatataatta
    22681 aatatgctat tgatatattt gtacccttaa ctattgttat cttttaaatg ataatgatat
    22741 ttatttaaat actctttatt aacaatttat aaaacttaat tgtaaaaaat acttattaat
    22801 agtaaaataa agtgaatcaa ttatattata attgctaaag agagtgaggt gtagctattt
    22861 gaaaaaaaat agattaatag caaagaatat atcaatagca tttatagtac tattcttttt
    22921 tagtgtattt acattttttt atgtaggtaa tattaataga gtgttagaat atgaaacaaa
    22981 tgacataata acagttacaa ttgctggatg gattatactt tcatttttat ttttaggtat
    23041 tataatttac atattatatt caaaagcaaa tagtcaaaaa actatagaaa aagtagcata
    23101 tacggatttt gtaacaggtt attccaactg gagaaagttt gaattagatg ttacaaattt
    23161 attaaagaaa acatcacaaa ataataaata tgcaatggtc atattcgata ttgataaatt
    23221 taaagcaatt aatgatatat atggccataa aaagggaaat ttaatattaa aagatattgc
    23281 agatacttta aatgaattga ctgatatcaa tgaaactttt gctcgtgtaa gtgctgataa
    23341 tttcaatata ttattaacat ataacaaaaa agaggatata ataaatatta tcaaaaagat
    23401 tatggcaaat aatgaacttg taaacttatc ttttggaatt tatgaaatca aagataagga
    23461 tttatctgta agtgtatata gtgatagagc ttcacttgca aaatcatcaa taaaaaataa
    23521 tagtgatgta aattttgcat tttttaatga caaattaaga gagaaattat tatttgaaga
    23581 taagatagaa aaagaaatgg aatatgctct tgaaagtggg caattcgtaa tgtatttaca
    23641 accaaaatac aatattaaat tagataaatt ttgtggaagt gaagccctag tcagatggca
    23701 atatacagaa aaagaggtca tatatccagg tgattttatt cctatatttg aaaaaaatgg
    23761 atttattaga aagattgata tgtacatatt agaacaagct tgtaaagaaa tccggtcttt
    23821 atttgataaa ggaatttcac ctttacctat atctgtaaac ttctcaagag ttgatttttt
    23881 taaaaaagat tttattgaaa acatagtaaa tatatgtgat agatataaaa taccatatag
    23941 tttaatagaa attgaaatta ctgaatctag tatgtttgga gatactgata ctctatttaa
    24001 tgttagtaga aacctacagg atattggctt tatagttgca atggatgatt ttggctctgg
    24061 atattcttct gtaaatatgc ttaaaaatat accattaaat gtaataaaat tagatagagg
    24121 attttttgtt gatgataaag atgttgataa gagtcaaatt gttataaaaa gcatagtttc
    24181 tctcattaag caattaggaa taagggttgt tgctgaagga attgaaacaa gaagtcaaat
    24241 agaaatgtta aaaaaagcaa attgtgatat tgttcaagga tattattttt caaaaccatt
    24301 accaattaaa gaatttgaaa aattagtcta taaaatatag tcagcgagtc ttaaatggga
    24361 ggtggtgatt aagtgataag agcaaaatcg ttaaaaaatg tactgagtat tgttttaata
    24421 tttttattta caataatttc tttttctgat tttgcattta aaactaatgt ccaggaagaa
    24481 gaaaatagta aaattaattt aagagaaata tccctacaaa gttccaatgc tataaaaata
    24541 aaattagata gttctctatc ctttattaaa agtgtggcaa atatggtttc ttattttaat
    24601 actatagata actcaaaaat agttccatta ttagctaata tatcaaaaga atctgacttt
    24661 caaagaatct ctattgtatc tcctgatgga ataagtcata ccagtgatgg caaaattatc
    24721 aatgtgtcaa agtatcagta ttttaagaaa gctattaaag gagaaagtaa tatatctgaa
    24781 gttgtgaaat ctccaattga tggaaaagat acttttgtta tagctactcc tgtatttaat
    24841 aagaataaca aaataattgg tgttttatac ggttcttact acaatgataa attagctgaa
    24901 tttatagata taacaagttt taatagtgaa gggtacatag atatatttga atctagtggt
    24961 caatttgttt taaaatcttc acatacaaac aaactgatta agtcaagtag taacatatat
    25021 gatatattta aaaaagcttc ttttgatgat ggttatagct ataaaaaaat atatgaagat
    25081 acaaaaaata acaagagtgg ctttacctca tatgaataca aaggagaaaa tcgttatgct
    25141 acttatacac ccattggtgt aaatgactgg tatgtaattt ctgtgatacc acaatatact
    25201 gtaagaagaa acattgataa aataaatcaa ttagcatttt ctcttatttt caaggtattc
    25261 ttattgttta ttatgcttat aatatatatt atttataaaa acaataaatc tcagaaagat
    25321 atattaaaag ctaacaaaga aatctcatct attacaaata gcattcctgg aggagtacaa
    25381 aagtgtaccc tgggtgaaac atgcaatatt aattttttaa gtgatggatt tatagagttg
    25441 tttggttata caagagaaga aataaaaaca ttgtttaata atgattttta tagtttaata
    25501 cataaagatg atgttgaaag aataaaaaaa gaaattttta aacaacttta caaaaataaa
    25561 actattgaat tagaatatag gattataaca aaaaatggta atacagtatg ggttttagat
    25621 aaaggggagc ttataacaga acctgatgga aaagaatatt tttgttgtgt aactgtagat
    25681 attactagaa caaaacaatt agaacaagag atggaacaaa aaaatctaga acttgaaatg
    25741 atatcagaaa atgttttagg tggtataatt ataacagaat ttaatgatga ttttactata
    25801 aaatacgcta actctggtta tctttcaatg attggatata cacgtgaaca attagaaaat
    25861 gaacttaaat acaaagcttg taatcttgtt ttttatgagg ataaaaagaa ggctcttgaa
    25921 agtatacaac atcaattaaa cacaaaagga atagctgtat atcaacatag aataagaaga
    25981 agaaatggta atattatttg ggtttctata aaaggaaggc ttattgttga tgatgatggt
    26041 attgaaaaag gtatttggat tctaaatgat ataacagatt taaaaaatgc agaacaaaaa
    26101 cttaaaataa atgaagaaag atttagaatt gcattaaagc aaacatcaaa tactatattt
    26161 gagtatgata taaaaacaaa gtcactttta aatactagta aagagcttga taaatataat
    26221 atttataaaa ttactaaaaa cgttccatat tctttagtag aatcaggagt tattcataaa
    26281 gattttagtg atgattttat aaacatgtat gaaaatgtaa taaatggagc aaaaaaagca
    26341 agttgtgtag ttaagatgaa acttccagat gaaaattata tatggaataa agttaccttg
    26401 actactattt ttgatgaaga tggtaatcct gtaagagcaa ttggtataca ggaagatata
    26461 agcaaacaaa aggaagcaga gataagatac aatcaagaag gtaagtatca ttcagctata
    26521 ttgtcggaag caatgataac ctatgaaata aatgtatcaa aggatacttt tatcaaagga
    26581 aatgaaagtt ggcaaaaacc atttggaatt aagcctgaca ataactattc tcaaatggta
    26641 aaaactatag caaatagtat tgtacataaa gacaataaag aaacattttt aaatacattt
    26701 ttatgtgaaa acttattgga tgcatataaa aataatgtga ctgaaataaa attagaatat
    26761 cgaagaatga atcaagaaaa taaaatgatt tgggtcattt gtacaatgca cttaataaaa
    26821 gattctatta cgaacgatat aaaagcactt gcttatgtta aagatattga caagcaaaaa
    26881 aatgaagaaa ttagattaaa attaaaagct gaaagagata ctcttacagg attatataat
    26941 aaaggtacta cagaaaaatt gattaatgat ttcttgaact ctgaggaagc aagtttagga
    27001 atgcatgcat ttttaattgt tgatatagat aattttaaat ctgtgaatga taatttagga
    27061 catgtatttg gagataaagt attatttgaa gtttctaaaa acctaaaacc tatatttaga
    27121 aaagatgata tagtaggtag aattggtgga gatgaattta tagtattctt aaaaaatatt
    27181 cagtcttttg agaatatcaa aaagaaagca gaaaaaatat gcgatatatt tagaaattct
    27241 tatacagaaa ataaaaagac atataaaata tctggaacag ttggaatttc atttgtacca
    27301 gaacatggaa ctgtatttga agaactttat aaaaaagcag acatagcact ttattatgca
    27361 aagagcaaag gaaaagataa gtatgcactt tataatgatt gtatctacca aaatgaactt
    27421 gaaaataata taagtgataa taatataaaa ttagcagata aatgtgagaa atccaaacca
    27481 gtacttaaag aaattcttga ttctattgat aattatatct atatagtgaa tccaaatact
    27541 tatgaacttc tttttatcaa taataaggtg tctcgtttgg atttagagat aaaattagga
    27601 gaaacctgtt ataaatcact attaaaatct gatagaccat gtaataattg ccctcttaac
    27661 ggattagaag aaaataagca ttcaaaattc aaaatagaga caaatacatt tggtaaaaat
    27721 atcagtatag caagttggat taattgcata gatggagaat acaactgtct tatagagtgt
    27781 atagattctt ctttatacaa aaataaataa aaaaggacta tgaagatatg ttaaatagta
    27841 taactttgat acttggtata atatttacaa tttactattt ttatctcaaa atagtttttg
    27901 gaggaatttc atttagtgag attttcttag ttgtaggaat tgtactaatt atctatcaaa
    27961 tatttaagaa aaaaattaaa gaaaagaagg ttttttatag ggtgttaaaa ataataatca
    28021 gcattttttt aatagtattt gtagttactg agagtctaat tattttttat cccaaaaata
    28081 gtttagaatc aaaaagtgat tatctcttaa ttttaggagc ttctgtaaaa aagactacac
    28141 caagtacaac cctgaagggt aggttagaca ctgcattgaa atacctaaaa attaatgata
    28201 attgttatgt ggtagtatct ggtggtaaag gaagtggaga aaaaataact gaggcaaaag
    28261 ctatgaaaga ttatcttata aaaaatggta tagataaaaa taggataata gaagaggata
    28321 aatccacgaa tacttatgag aattttaaat attcaaaatt gaagatagaa gaacatagtc
    28381 aaagaaaact aagcgattta aaagtaaaaa tagtaacaac agattttcat gttctcagaa
    28441 gtaaaatatt agcatataga aatggatata aaaatacgtc tttttatgct agtaaatcaa
    28501 aactttcatt tgtaccaact tactatacaa gagaattttt tgcattatgg aaaacaatca
    28561 tttttgatag ataataaata aaaagactag atataaactc atatctagtc ttttctattc
    28621 ccttaattct aatccatttt ccaactttac ttgttgtaga aatttcaaca ttgggattta
    28681 caagtaattg cttataagaa gttttatatt ttacgattcc aaaatataat tttccttcat
    28741 aatccattat aaatccgaat ggtcttactc ttggtttatt atcttcaact gtagcaaaat
    28801 agaatgttga gttttcttta aaaaaattca ttattttttc atgattaaat cctctttgta
    28861 tcttatacta atataatgaa ta
//
LOCUS       DAEPXW010000048        28542 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.049, whole genome shotgun sequence.
ACCESSION   DAEPXW010000048 DAEPXW010000000
VERSION     DAEPXW010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28542
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.049"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            93..443
                     /locus_tag="KRM55_002096"
     CDS             93..443
                     /locus_tag="KRM55_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH1594336.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            462..2105
                     /locus_tag="KRM55_002097"
     CDS             462..2105
                     /locus_tag="KRM55_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBH1594337.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2186..4243
                     /gene="recG"
                     /locus_tag="KRM55_002098"
     CDS             2186..4243
                     /gene="recG"
                     /locus_tag="KRM55_002098"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBH1594338.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4302..4856
                     /gene="rsmD"
                     /locus_tag="KRM55_002099"
     CDS             4302..4856
                     /gene="rsmD"
                     /locus_tag="KRM55_002099"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBH1594339.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4858..5355
                     /gene="coaD"
                     /locus_tag="KRM55_002100"
     CDS             4858..5355
                     /gene="coaD"
                     /locus_tag="KRM55_002100"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBH1594340.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5359..5883
                     /locus_tag="KRM55_002101"
     CDS             5359..5883
                     /locus_tag="KRM55_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594341.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6227..8146
                     /locus_tag="KRM55_002102"
     CDS             6227..8146
                     /locus_tag="KRM55_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1594342.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8159..8446
                     /locus_tag="KRM55_002103"
     CDS             8159..8446
                     /locus_tag="KRM55_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1594343.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            8579..9838
                     /locus_tag="KRM55_002104"
     CDS             8579..9838
                     /locus_tag="KRM55_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBH1594344.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNIFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            9841..10581
                     /locus_tag="KRM55_002105"
     CDS             9841..10581
                     /locus_tag="KRM55_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1594345.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVGPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            10922..12214
                     /locus_tag="KRM55_002106"
     CDS             10922..12214
                     /locus_tag="KRM55_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH1594346.1"
                     /translation="MEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSKKDGEKE
                     KLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISAGEGPDV
                     GYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAANPGVLY
                     YNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFGNLNWNW
                     YPYLWQAGGDIFNDDLKSVKFNDKSGLEAAKFLKELQAYVPEDSLSKDSNEMIESVFG
                     PGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSSAKNKEL
                     AYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPLVVGPHG
                     VEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            12312..13229
                     /locus_tag="KRM55_002107"
     CDS             12312..13229
                     /locus_tag="KRM55_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH1594347.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            13245..14054
                     /locus_tag="KRM55_002108"
     CDS             13245..14054
                     /locus_tag="KRM55_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH1594348.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            14112..15860
                     /locus_tag="KRM55_002109"
     CDS             14112..15860
                     /locus_tag="KRM55_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBH1594349.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDMLVEQYLPQTFWVEGQVPEDFEENNFNIGIDIFKSFGYEDEEKACTIDVP
                     VEVKNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIIDNYLKELASLGEKV
                     ATIIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVSTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGRDYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            16121..17143
                     /locus_tag="KRM55_002110"
     CDS             16121..17143
                     /locus_tag="KRM55_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBH1594350.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGVTKEAPETSRRAWVKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDREILS
                     ALIEKR"
     gene            17148..19454
                     /locus_tag="KRM55_002111"
     CDS             17148..19454
                     /locus_tag="KRM55_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1594351.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSERRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYVLS
                     SLSLKIFSQNIRNVRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSITYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFHMDIKNIGKLRIVNFNYQYVLLNF
                     ENKNIYPKEIALEISEGIVLECDLCEGKIDERGILYRVNNIDSIMQNLFLRDEMMDWI
                     LQNKKILDSKPNEKKEKSIDEFEPMEYI"
     gene            19426..20541
                     /locus_tag="KRM55_002112"
     CDS             19426..20541
                     /locus_tag="KRM55_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594352.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSAKYFILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVKIETNSSKSDKKRYLYIYQNMKENWSMYNNF
                     YIEIQNKNKSSQKINLSIQSKNMLEFRLKEGSEVFLEDKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEKSNVVLDSSMLSNIVSWGITFIPSDEEHNNIIIKKISLLSEEKL
                     SFLHNIKITGNEEVQIPVLGQGISQYEVLGLESDSKIKYSLIGKQDNLSISQKGKLTL
                     NNKSKPGQIILQVDVDDKFKIGKKITLTESWSINKKDKDGVPYTLVSPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            20559..21977
                     /locus_tag="KRM55_002113"
     CDS             20559..21977
                     /locus_tag="KRM55_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBH1594353.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCVYNIGVLFIFKYLAFAL
                     RNISELINTELTIPNIILPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTMQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMLGG
                     NGVIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQVKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            21993..23201
                     /locus_tag="KRM55_002114"
     CDS             21993..23201
                     /locus_tag="KRM55_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594354.1"
                     /translation="MNRFFKVRLITAIMFLVVLFAFSIFNICYYGKDMIQEIKNSVAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSSVKDTSGKMHYTY
                     FAKAPNPIGVISDRVRKFSEEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELIEQLNKK
                     YNINLDENHYYRDKENYNSIVYPKSFLGSMGRKSGILYGGIDDFALIYPKFKTNYTYY
                     TDSKFQKFELKGRFEESLILSYPFNADLNLMDGQSDKYSTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISIYPQN
                     LTKEFFPFCE"
     gene            complement(23275..24663)
                     /locus_tag="KRM55_002115"
     CDS             complement(23275..24663)
                     /locus_tag="KRM55_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBH1594355.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            25004..26338
                     /locus_tag="KRM55_002116"
     CDS             25004..26338
                     /locus_tag="KRM55_002116"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBH1594356.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(26480..27397)
                     /locus_tag="KRM55_002117"
     CDS             complement(26480..27397)
                     /locus_tag="KRM55_002117"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBH1594357.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            27605..28489
                     /locus_tag="KRM55_002118"
     CDS             27605..28489
                     /locus_tag="KRM55_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBH1594358.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWTQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
BASE COUNT        11162 a         3056 c         5064 g         9260 t
ORIGIN      
        1 tatgattata attttatata ataaataagt aaaaatagta aaaaataaat taagaaatgt
       61 ttttaataaa aataagctta agggggtcaa ccatgagtgc aaaggtaacg aatcaatatg
      121 gaaatataga aatagataat caagtaatag ctcaagtcgt atatagagct gcaatggaaa
      181 gttatggctt agtaggttta gcatataagt ctaaaggaat agtagagcta ttaaaaggcg
      241 agaacgcaac taaaggtgta agagttgagg aagtagaaga agatgccata gcaatcgaac
      301 tttatgttat aatacaatat ggtacaaata tatctactgt tgccaataat ataatagata
      361 gagtaaaata tgtagttgaa aaaatgactg gcgtaagagt tactagaatt gatattaatg
      421 tacaaggaat aagagttaag taatttcata ggaggaaaca aatgattcaa tatatagatg
      481 gtaaaaggtt aagggagatg tttatttcag gtgcaaacaa tctccaaaac aataaagagt
      541 tagttgacaa gttaaatgta ttccctgtac cagatggaga tacaggaact aatatgtcat
      601 taacaatatc ttatgcctta aaagaattag caaaagttga aaatgataat atatcagata
      661 tcggaaaagc attatctaaa ggttctttaa tgggagctag aggaaactca ggagttatac
      721 tttcacaaat aatcagaggt atagctaaat ctatagaagg aaaaagtaaa ttatcaacag
      781 aagatttagc aaaagctttt aaaaatggtt cagacacagc atataaagct gtaataaaac
      841 caattgaagg aactatactt actgtagtta gagaaagtgg agagtttgca ataaaaactg
      901 cgaaaaaaga gaaagatgta gtaaagtttt taagtatgct tgtgaaggaa tcaaattctt
      961 cattagaaag aactccagac cttctaaaga atctaaaaga agctggtgtg gttgactctg
     1021 gtggaaaggg tcttgtactt atatatgaag gaatgttagc ttctataaaa ggcgataaca
     1081 tagaaataaa aaatgttgac ctagatacta atatttcaac aagtatggat tttgcaaaga
     1141 gtactactag cacagatgat ataaaatatt gctattgtac agaatttatt ttagaaagtt
     1201 ctaaggtaga agatactaaa ataagagaca taatgatggc ttatggtgat agcctagcag
     1261 tagttggaga tgatggagtc ataaaggtac atgtacacac taatgaccca ggaaatgtac
     1321 ttcaagaagc tctaaagtac ggtcaattat taactataaa aatagaaaat atgaagttac
     1381 aacatgaaaa tacattactg gatgtagaag aaaagaaaga aaatgatagt gaacctttag
     1441 aagaagaaaa agagtttggg tttatagcta cttctatggg tgaaggtttg gcaaatatat
     1501 ttaaagattt cggagttgac catataatag aaggtggtca aactatgaat ccaagtactg
     1561 aagattttat gaatgctata aagcatataa atgctaaaaa tatatttatt ttcccaaata
     1621 acagcaatat aataatggct gctaatcagg caaaagaatt gagtgataaa aatataatag
     1681 ttatacctac aaaaaatacg cctcaaggat ttgctgcatt agtaactttt aatggagaat
     1741 taagcgaaga tgaaaataaa gaagctatga tgaatgcttt aaactcagtt aaatcaggtc
     1801 aagtaacttt tgctgttagg gatacagtga tgaatgaaat tgatgttaaa gaaggtaata
     1861 taattggaat tgcagaagga aatttattat cagcaggaga ttatgtggat gaagtaacat
     1921 caaaccttat tgaaaagttg gttgatgaag atactgctat aataacatta ttctttggtg
     1981 aagatgttac agaatctcaa gcaaatgaac tacgtacttc tttagaagaa aagtttgaag
     2041 atgtagatgt agagttatat tatggaggac aacctcttta ttattactta atttcagttg
     2101 aataatgatt ataagaacct gtatgaccaa gtagctttta taaaattggt tgtacaggat
     2161 ttttgtgtag taggtgatat atttgttgga tttatataaa gatgttcaat atgttaaggg
     2221 aataggacct aaaaaagcag ataaattaaa taaactgggt atatttacac taaaagacct
     2281 attgtattat tttccaagac aatttgaaga tagaaataat ctaaagaaaa tagcacaatt
     2341 agaagatggt gagaaagtta cgataaaagc agtaatatca agtataaata catttagccc
     2401 aaaagaaggt atgactttaa caaagattga tgtaaaagat gagacaggct cggctaaatt
     2461 agtgtttttt aataagagtt atataaaaaa tacttttcgt ccaggagatt caatattagt
     2521 ttttgggaag gttaagaaaa aatttaataa cttagaactt acatcatgtg aattagaata
     2581 tcttactaat tcacctaaga atacatgtag atttatgcct gtgtaccagc ttacatacgg
     2641 tgttacaaat aaagaaatta tgagtataat tagaacagta cttgaagata aagaattaat
     2701 tatacaagaa tatatgccac aaagaattat agaaaaatat aggctatgta gtatagattt
     2761 tgcagttaga aacatacatt caccaagtag taaggaatca ttaaaaatag ctttatatag
     2821 aattgtattt gaagaattac ttatactaca actagggttg tttgtattta aaagtggcag
     2881 aaataaagaa gatggaataa agtttgaaac aagtaaagac ttaaaaaaaa taataagtgc
     2941 tttaccattt aaactgacta aagctcaaaa cagggcatta gatgaaatta tacaagatat
     3001 gaatttagag aaaataatga atagattggt acaaggtgat gtagggagtg gtaaaacagt
     3061 agtagctctc ttagcacttg caaattgtgt tttaaatggt tatcagggcg ctttgatggc
     3121 acctacagag atattagcag ggcaacatta tatttcactt actgagtctc taaaagattt
     3181 tggaataaat gtaggtctat taataggtag tcttacaaaa aaacaaaagg atacagtatt
     3241 ggaacaaata aagaataatg agattgatat attaataggt acacatgcac taattgaaga
     3301 taaggttgaa tttaataata ttggtttagt tataacagat gaacaacata gatttggtgt
     3361 tatgcaaagg agcaaacttt cattgaaagg agcaaatcct gatatattag taatgacagc
     3421 aacaccaata ccaagaactt tagcacttat actctatgga gatttagata tttctattat
     3481 agatgaactt cctccaggaa gacagccaat agaaacaatt gctattgaaa aaagtaagcg
     3541 agatagagca tataataatc ttgtaagaag agaggttgaa tcaggaagac aagtgtacat
     3601 tgtatgtccc ttggtagaag aaagtgaagc catagaagcc aaatcagcag ttgaacttgt
     3661 tgaggagtta agagcggaat attttcacga cttaaggctt gggttgcttc atggtaaaat
     3721 gaagtcaagt gaaaaagatg aagtaatgag actttttaaa gataaagaaa tagatatttt
     3781 agtttcaaca acagtaatag aagttggtgt caatgtgcca aatgcaacat taatgataat
     3841 agaaaatgca gaaagatttg gacttgcaca attacatcag cttagagggc gagttggaag
     3901 aggtagtcat aaatcgtatt gtgtactaat ttatgattct aaaacagatg tatgtagaca
     3961 aagaatggct ataatggaag agaccaatga tggttttaag atttcagaga aggatttaga
     4021 aataagagga cctggggaat tttttgggac aaggcagcat ggtcttccag aacttaaggt
     4081 agcaaactta tttaagcata taaaaatact gaagttagca cagcaagaag ctcgatatat
     4141 attgggtgaa gataataatc tacaattaaa agaaaacatg gcactcaaaa aagaaattat
     4201 agataaattt aaagatacat tgaaagaaat ttcattaaat taattttaaa ttgtgttaaa
     4261 atattactaa tgtaataatg tgctgaaggg agattgtcat attgagagta atttcaggaa
     4321 aagcgagagg attaaaacta aatactccaa aaaatgaaga tgtaaggcca actacagata
     4381 gagtaaaaga gtctctattt aatatgataa attcatatat aatggaaagt gaagttctgg
     4441 atttatttgc tgggactggt tctttaggaa tagagtgctt atctaggggt gccaagtcat
     4501 gtacttttgt agatatcagt aaggaaagca tagatattgt taagtccaat ataaaaaagg
     4561 caagagttga aagtgaaagt attattttaa accttgattt taagactgca atagataaac
     4621 ttaaattaca aaatagtaaa tttgacataa tttttatgga ccctccgtat tataaaaata
     4681 tgtttataga agctattgaa aaaattgata attctaatct attgaacgaa gatggaataa
     4741 tagttgtaga acatgatacg aatgatttat ttccagataa gatatgtaaa ttggagaaaa
     4801 ctagagataa gaaatatgga aatactacat taacttttta taagatggag gcataatatg
     4861 gaaaataaac ctagaaaagc tatatttgca ggaagttttg acccaattac taatggacat
     4921 ttagatatta tttgcagggc ttcgaagtta tttgacgaat tacaaatagg agtattaaat
     4981 aatcctaata aaaagggtct atttagcttt gatgaaagag taaaacttat agaaaaaagt
     5041 acaagccatt taaataatat aaaagttgtg acttttgatg gtttattaat aaattactgt
     5101 caggaaaatg ggattggagc attagttaga ggtgtgagaa gtggtgctga tgttgattat
     5161 gaacttcaga tggcgcatat gaatagagag cttaatccag atatagagac tataatttta
     5221 ccaagttgta caaaatattc atttataagt tcatctttaa taaaagaggt tttgctcttt
     5281 gatgctgata taaaaaattt ggttccaaag attgttttgg aagaattaaa gaaaaaaact
     5341 agtgggggta attgatatat gaagatagat ttagaaatga ttgaactatt tgagcagtta
     5401 gaggagatat ttagaagtgc ttctacaatc cctttctcac ataaatgcac agtggataaa
     5461 gatgaggttt tagcaataat taatgatata agaactttaa taccagaaga agtaacacag
     5521 gcagtatgga ttaataaaga aagaaataaa ataataagtc aagctaagca agatgctaca
     5581 aatatagttg aacaagcgaa aaaagaagct gagagaatac aacaagaata tcaagataat
     5641 atagaggaat taaagaaaaa ttctgaagat gtagtaaagg catatgtaga atccagtgaa
     5701 cctgttgttc aagcagacca aagagcaaaa gatatagttg atagagctga gagaatagcc
     5761 aatgagataa gaattgggtc aattgaatat gcagaggatg tgctttctag tgttgagtat
     5821 aatttaagag aaatattaga agaagtaaaa agagataaag ctgaacttag acctaaaaaa
     5881 taaattttaa ataaataaaa atggagctat cacacaaaaa attccaattt atgtgtgata
     5941 gctctctttt aatatagcaa ttttttgtta tataattgtg ctttttagat tacttatatc
     6001 ttattttgat attataatgt agtttaatct tttatttgtt gaaatcaact tatttatttg
     6061 tataaataat ataggttatt ttcaaatttt tttaataatt ttaccactgt cttcttttag
     6121 attagagtta gactgtgcaa aattataaaa taatactaaa tcatgtgcaa ttatttggta
     6181 tggcactaca tgtagaaaat atagataata aaattaagga ggtagtatga aggaaagggc
     6241 taaaaaaata ttagatttta ttattaaaaa taacaatgta acatcacaag aactacaaga
     6301 aaagtttaat gtttcaaaga gaactattta ttacgatatt ctagctataa atgaacaact
     6361 aggaaaaagt ggtaatataa aaaatgtaaa acacaaattt atatttgaag gtaatttatg
     6421 tgatgcaagg aaaataattt caaccgaaga agataaattt ttagatagtg attacagaaa
     6481 aacttttata ttaaacaaga tattacttgg cgaaaaaata tcaatagaaa aactaacaaa
     6541 tgaaatgtta ctttcaaaaa acacagtagt acaaacaata actgatgtaa aaaaatacct
     6601 tcaaacaatg gggttaagat tagagtataa gggaaagtac aaaattatag gtgatgaata
     6661 cgttattaga gagctgtttc tgataattgt tcaagaaaat gtactggaaa ttaattctat
     6721 aagtgaggaa gtaagtagtt tcgatacaaa aggacatata aaacttactg attattcttt
     6781 attaaatcta actaagtttg tggaatttct aaataaaagg ataagagatg ggaaaacatt
     6841 atactcatat aaatatctaa atgaagctaa aaaaattagt tactttagta attgtaaaga
     6901 acttttatgt gaagaagcta atgaaaatga acaagcctat atatgcactt acataagttc
     6961 acttcccagc ttaaatagtg aagttaagga agatgttgtt gaagaatatg tagataaact
     7021 tatagataag tttgaagtaa atacagcaat aaaattagaa agtaagcatg agtttaagaa
     7081 aaatatttta aggcacctcc actcttctta caacagaata cgatttaagt ttcctattag
     7141 aaatccaatg ttagatgaga ctaagtataa acatgagtca ctttataaaa ttataaaatc
     7201 aattatagag aatgaagaag agtttcctgt atttgagggg ataagagaag aagaaatagg
     7261 atttatagca gcgtattttg gaggatattt aagagggtct agggataatg gtctaagaag
     7321 aaataaagtc ttactagttt gtcctaatgg tcttatggta tcaaagagtt tggaaataca
     7381 actatataaa tacataccaa ccatagaaat agtaggtata gtatccatta agcaactaaa
     7441 agaagtaaat gtatactacg attacataat tacaactata gatatacaaa atgtaaacaa
     7501 cgtaattgtt gtaaatcctc ttttaacatc atcagatgtt caattactta tgaacaaact
     7561 aataagtgta aaagaaaacg agaagtattt caatcttgaa ttaataatac aagctataag
     7621 aaaaaatgga gttatcaata atgaagaagc actaaaagct gatttattaa acataataca
     7681 caagatagat gaaggagaga tgtatcaacc aatgttaaag gaattaatta atgcagaaag
     7741 ggtcaatata ataaaaaatg ttagagattg gaaagaagca ataaaaatag cctcaaagcc
     7801 attgttagaa gataactcta tagaagagtt atatatagaa aatatgataa agtcagttga
     7861 gaaatatgga ccatatattg ttttagctga tagatttgct ctaccacatg caagttctaa
     7921 agaaggagta aacaagcttg ctatgtcttt actaatagta gaagatgaag ttgatttatt
     7981 aggaaaacca gtaaatatat ttatggtatt agctgctgta gataacacta ctcacattag
     8041 agcattagca tcactatcag agatgatgta cgaggaagaa aatgtaaaac taataattaa
     8101 tggtgataaa agttcaatac tagaacttat aaataagcaa aattaggagg aatgaaaaat
     8161 gaagatatta gcagtatgtg gttttggtgt aggttcatca atggtattaa aaatgacaat
     8221 acaaaaggct ctaaagcagt taggtataga atgtgaagta gaaaatacag atataaattc
     8281 agctagaggt gctgattgtg actgtatatt cacaagtcaa gaattgttaa atgaattaaa
     8341 aggaacttgt aatgtagatg tatatccagt taaaaagtac atggatttag cagaagtcac
     8401 agaagttgtt caaacttttt taagtgataa aaatgataag aaatagtata agttttaaaa
     8461 agtaaattta agttaatcag aataaaataa aaacttacta aattcaaaaa tagtaagaaa
     8521 gagaggaggg atttagtggt agaaaactta aacagttgac ctatcactaa aaaatataat
     8581 gcttgatttt atttcaaata atattttacg taatccatct atgttaattg gattaatagc
     8641 agcatttggt cttgtattac agaagaagaa agcatctgat gttataaagg ggtcactact
     8701 tgcagctttc ggaattataa ttatggagac tggaacaggt atgttagtta gttcaatagc
     8761 accaattaat ggagctttcc aaagtataag tggtggtgca gtaacaaaag gtttaagtga
     8821 tgttactttt actgcaagtt atggtggaat tataggttta gcaatgtttg cgggtttagc
     8881 tattcaccta atgatagcaa gatttactcc tattaagaca atcttcttaa caggtcacat
     8941 gctttattgg ttcccattca tatttgtagc ttcaggagtt gaagctggat taaatggtgg
     9001 agtattaata gcttttgcag cagtattatc agcactctat tggtcaataa tgccttggtt
     9061 attaagaaaa tatgtgtttg atgttatagg agatgattct tttacattag gtcatccatc
     9121 tggttgttta gcacttatat caggatttgt tgctaaatta gtaggaaata aagaaaaatc
     9181 tacagaagat ataaacatac ctcaaagttt atcatttttt agagaaatat ctataagtgg
     9241 tggaatggca gtgtttttaa tgtttatagt tgttgggata gtaataccag gtgcgtttaa
     9301 agatagtaat gagtttattg gaacgtatgc aataaagcaa ggtctttctt ttggagcagg
     9361 tcttataata atgcttcatg gggtaagaat gctaataaat caaataatgc cagcatttca
     9421 aggtatatct gaaaaagttg tgccaaatgc attacctgct tttgactgtc caatattatt
     9481 taattataaa ccaaatgctg tattaatagg atttttagtt gctatgctaa catctacagc
     9541 tatgatttta atatgtaact actttaatat atttaatttg ctacttatac cacttgttat
     9601 aacttcattc tttgagtgtg gagcagcagc agtaatagga gaatcacaag gtggtatacg
     9661 tggagctata ataggtacag ctatagctgc aatatttatg gtagttttag taggaatatc
     9721 tgctgtaatt tactcaggaa ctattcaaaa ttggatacta atatttggag gtaatgacct
     9781 ttcattattt ggtataatca gtaggtttat aggttcacta tttggaggaa tattatagat
     9841 atgaaattta aatacataga tgagataaga agattaattg atataataga aaacgaagaa
     9901 aaagtcaata tggaaaaagc agtacaaatc tttgttgaag caatagaaag taaaaatgct
     9961 atattttcat ttggagcttc acatgcagga atattaacag aagaattatt ctatagagca
    10021 ggtggctgtg ttcttataaa tccagtattt gcaaaatctc taatgttaga tacagcgcct
    10081 ataactcaca caagtaagat ggaaagatta gaaggatatg gtacagctct agctgataaa
    10141 actccaatta aaaaaggaga tgtagttata gttcattcag tatctggtag aaatccagta
    10201 agtatagagt ttgctatgaa agctaaggaa aataaggcaa tagtaatatg tataactaat
    10261 ttaagttact caaaaagtgt atcttcaaga cattcttcag gaaaaaaact ttatgaagta
    10321 tgcgatttag tgatagataa tcatggtcaa aagggagatg cctgtgtaga gatagatgga
    10381 ttaaaccaaa aagttggtcc aacttctact gtaatagcaa ctactgtgat gaactctatt
    10441 atagctcaag ctactcagga attagttaat aaagggctaa agaatcctcc gattttctat
    10501 agtgccaata ttgatggtgg agatgagtta aataagaaga tttttgatga atataaaagt
    10561 gtaattcatt atgaatatta aggttaaaaa aatatgttaa tgaactttga agtttatcaa
    10621 caaagaatat taataatata taataaatgc tatcatttaa aagctgtagg taaaaatcta
    10681 cagcttttta ttattgtaga ttaaaaaggt gcgtaattaa attttaaatt ggagaaaata
    10741 aattggaagg tatcaattat aaatattaga aacgttgtca tagaaaaaaa ctatattaaa
    10801 aaaaagtaca tagaaaaaac tgattagaca ataaatacat gctttgataa tattttaaat
    10861 ggagtgaaaa tgtgtagaat tataatgaaa aaagaaaata aaaataaaaa aagaaaataa
    10921 aatggaggga ataaaagtgg gtatgttaaa aaaattatgt tcactagcta tggtagcaat
    10981 tatgactaca acacttataa cagggtgttc aagtggaaat ggaaaagatt caaaaaagga
    11041 tggcgaaaaa gaaaaactag ttctttggat gccaccagta gaaaataata tgaaggaagt
    11101 ttgggaccct attttagata aatttgagga aaaaaataac tgtgaagtag atttacagat
    11161 aattccttgg gataattatt ctgaaaaatt tgcaacagct ataagtgctg gcgaaggtcc
    11221 agatgtagga tatatgtatg cagaaatgta tccacagttt atagaaagtg gagcagtaga
    11281 agatttgact aattatgcaa ctaaagagga taaagagcaa tctatttata taaaaacatc
    11341 tgaaatgatg ggtggaatgt atggtatgcc attccaagca gcaaatccag gggtattata
    11401 ctataacaag gatattttag agaaattagg agaaaaacct cctaaaacat gggaagattt
    11461 taaaagaatt tgtaaaaaag caacacaaga tactgatggt gatggaaaga tagaccaatg
    11521 gggattagct cagggatggg gagctaaaac ttttggtaac ttaaactgga actggtatcc
    11581 ttatttatgg caagctggtg gagatatatt taatgatgat ttaaaatcgg ttaaatttaa
    11641 tgataagagt ggtttagaag cagctaagtt cttaaaagaa ttacaagcat atgtgcctga
    11701 agattcttta tctaaagata gtaatgaaat gatagaaagt gtatttggac cagggaaagc
    11761 agcatttaca ataatgttat cttctgctgc aacaagtgta tttgatgaat cattcccgga
    11821 tttaaattgg ggatttgtaa ctggactaga agataagaaa gcagcaactt ttggagcagt
    11881 agaccattta tctttaatgt catctgcgaa aaataaagaa cttgcataca agttaataca
    11941 acatatgtta agtgttgaat caatgacaga atttcataaa gcaataccaa gagcaccaat
    12001 aacaaaaggt gaaccatatc aaggtgatga aagattcaaa gaaatggtgg aaaatgacaa
    12061 aaatgtatat agaccattag tagtaggacc tcatggagtt gaaatatatg aatatttatg
    12121 gaaagaactt caaactatga tttcaggaga taaaactcca aaacaagcgt tagatgatgc
    12181 tgcaaaatat tcaaatgatt tattagcaca ataaaagttt aaagctgtaa tatgttgtaa
    12241 aggactttac agattaaaat tagcattgta tttataaata caatgctaat atttatattg
    12301 gagaggataa aatggaaaac ttagttagag agtttgaaga aaattcaaaa agaaaaaaaa
    12361 caaaattaaa tattaaacca tatatgtata tattgccatt gggaataatt ttagtggcgt
    12421 tttatgtgat accaataata atgtcaatat actttagttt tacaaagtat aatattatta
    12481 gtccagctac ttttataggt ttagaaaatt ataaaaaatt atttacagat gaaacattaa
    12541 aagtatctat tataaatact attaaattta ctgttgttgt agtaccttgc caaactatat
    12601 tatcattgat tttggctgtt tggattacag gaaaaggaaa tagtaaaata gcttcatttg
    12661 ctaaaggtgc tatatttata ccagtattat catctatggt tttgataggt atggtatgga
    12721 gggctttatt gaatggagaa ggttctatta tatatcaggt attaggtgcc tttggaatag
    12781 aatcatctaa acttttagga gatagtaaga cagcattacc tacacttatg tttatatcta
    12841 tgtggaaaaa tatagggtat ttcatggtaa tttatatttc agctataatg aatttaccaa
    12901 aacactgcta tgaagtagcg aaggttgatg gggctacaaa acttcaagaa tttataaaaa
    12961 taactgtacc tttattgaaa ccaactacaa taatggttgt atttttaggg tcgatatggt
    13021 cattacaagt atttgactta atttatactg tgacaggtgg aggtccaggt atatctacta
    13081 tgagtatagt tatgcatgca tttaacttaa actttaaaaa ctttaattct ggatatgcaa
    13141 tgactgtagc aaacgtatta tttttgttaa tagcagtagt ttcgatttta caaaataagc
    13201 ttgtaagacg agacaattca gatttttaga aaggtaggta taatatgaaa acagcaagaa
    13261 gattattaag tgatggttta cttttattta tagcgtgtgc aagtttggta ccttttatat
    13321 acatgttgat aatatcattg aagataacat ataactcata tagtttggat atatcttttt
    13381 caacagtaac ccttcaaaac tatatagata tttttactaa aaaaggattt gcacaatatt
    13441 tttttaatac agcaatagta tctttttcag gtgtattatt aaatttagta tttagtacat
    13501 tagcaggata ttcttttgcg aagatggatt ttaaaggtag tgataagtta tttttattta
    13561 tgataatgac tttaattata ccttcccaag ttacaatgat accactatat ataataatga
    13621 aacacttagg atggataaat agttatcttg cacttattat gccaatacca actgcatttg
    13681 gcgtatttat aatgagacaa gctattttag gagtaccaaa agagttatta gaatcagcaa
    13741 agatagatgg ttgctcggat tttagaattt taatacaaat agtgttgcct ttaattaaac
    13801 cagcattaat tacactagca atatttactt ttatgggagc atggaacgag tttatgtggc
    13861 ctcttatagc tacaactaaa gatgcaatga gaacattaac agttggatta tctactctta
    13921 agacattcca gataactaat tatggacaga tgatggcagg ggctacaata acatttttac
    13981 ctccatttat tttctatttg attttacaga gtaaatttgt tgaaggtgtg tctttgtctg
    14041 gtataaaagg ttaaatagtc taatttaata atatataaag aaacttatat aaatatggag
    14101 gaatttaaac tatggaaatt tcatatgtac tgaaagattg cacattcaaa cacaataaat
    14161 actcagttgt agaagctgaa acttggaaag ataaggattt ggatattgta gtagctaaag
    14221 gtgaaaaatt tgcatttcaa attatgttaa aagcaacaga agaatttaat tgtacaattg
    14281 ataaaagtag tgctatatca tggaaaggcc tgggaaatag agtaagatta gcattaaatg
    14341 tacctaatag tttagaaaat aattttagta taaatatact aggatatgtt caagatgata
    14401 caaaagcatt tgtgaatgat gctattttaa gggataaaga tatgttagta gagcaatact
    14461 tgcctcaaac attttgggtc gaaggtcaag ttccggaaga ttttgaagaa aataacttta
    14521 atataggtat tgatatattt aaaagctttg gatatgaaga tgaagaaaaa gcttgtacaa
    14581 ttgacgttcc tgtagaagta aaaaatgttg tattaaagcc tttagatgaa agtaagttct
    14641 ttttagattt atggcaacat ccaagctgtc tagctagaat gtataaagtt gagctatggt
    14701 ctgatataca ttttgaaata atcgataact atctaaaaga attagcttct ttaggagaaa
    14761 aagttgcaac aattatagtt tcagattatc catgggcagg gcaaagttgt tataaagttt
    14821 ataaaaatcc atcaaactta tatgaatata acatggtaag tgtatcaaaa ggattggatg
    14881 gaaagattaa atgtaacttt gagagtatgg ataggtatat aagcatagct gataagtata
    14941 aaatggctaa ggagatagat ttatttggtc tattaggtaa ttggtgtgct ggtgagtttg
    15001 gaaatcctgt agaaggttat aaggacccta taagagtaag atattttgat gaaaaggata
    15061 aagtatttaa atttataaac aatacaaatg atttaaaaga atatatagga ttagtattaa
    15121 atcatttaat agagtgtgga ttatgggaca gagtaaggat tatagctgat gaaccaaata
    15181 atccagaagt agtcaaagag tgtatagaat ttataaattc tactgtaagt actcatcaag
    15241 ttaaatataa atcagcaact cacgaccaaa actttttaga cagagctaaa gatgaaattg
    15301 atgatatgtc aataaattta aaacttacta tacaaaatta taaagatata gaaagtctta
    15361 agaaaaaaat caatgacaag ggtgggatat tgacttggtt tgtatgctgt tttccagaga
    15421 aaccaaatag ttttttaagt tctccttttg tagaaaatag aataatagga tggtatactt
    15481 attactttgg tcttgatgga tttttaagat gggactataa tttatggaca gaagaccctt
    15541 ggaaagattc aagttacaaa ttccctattt ggaaagctgg agatatgttc tttgtttatc
    15601 ctggaaaaga tttaaagcca gttagaagtg ttagaatgga gaatttaaga tttggaatac
    15661 aggactttga gttatttaca atgttagaaa aagaaaaggg aagagattat atagaagttg
    15721 agcttatgca agaattatta aataaaaaag aaaatgctga aattaaaggt tttggtgaca
    15781 tagaactagg atattcactt gataattggg gatatgataa agttaaaaaa tatgtattag
    15841 agttgttaga cagagtataa aaaatataag agtgtctcaa aatgaacttt ttagttcatg
    15901 aggcactctt tttgtatgaa atcaatatag tttcattgtt tcaacaatga aaaataggat
    15961 tatttctatt ctaagacagc cctttagttt ttagttgtat tcaatgtttt aaaactaact
    16021 ataaacgcta taaagtttat aaatgacaat aattatatat aacatgatgt actttaattt
    16081 gctataatag ggattgaata atattatatg gaagataaca ttgtttgggg ggattaatat
    16141 aaaaagaata ggtattatta taatgttttt tttaagtata tcttttattg gattttatct
    16201 tgtaataaga gataacagtg atacagttaa gatgcaacga gggataaata taggtaatgc
    16261 actagaatca cctaaggatt ttccgtggga tgtaaaaatg tcaaataagt tttttgatga
    16321 tataaaagat gcaggttttg acacagtacg tataccagta aggttttctg attatacgtc
    16381 agattctgat aattttaaaa ttgatgaaga attttttaaa aagattgata aatatgtaga
    16441 ttatgcattg gataaagact taatagttgt gttggattta caccattttg aagaaattat
    16501 gaaagaacca agagttcata aagaaaagtt tttaaaaata tggcaacaga tagctaatag
    16561 gtatcaaaaa tatgataaaa aattggtatt tgaattatta aatgaaccta aagaaaattt
    16621 atattcacag ttactaaacg aatacattga agaagcaata aagataatta gaaaaactaa
    16681 ccctaaaaga actattatag taggaccata taatttctat caaattgatt atttgaatga
    16741 attaaatatt cctaaagatt ctaatatagt agtttccttt cactattacg agccaaatga
    16801 ttttgcattt caaggaaata tctatcataa gggatttgag cacttaagca atattacttg
    16861 ggaaggaaca aatgaacaaa tggattattt aaaaaaaagg tttgatactg tggaaaattg
    16921 ggcaaataaa aataaggtaa aaatcttctt gggtgaattt ggagtaacaa aagaagcacc
    16981 agaaacttca aggagagctt gggtaaaagc tgtaagagaa gaagctgaaa aacgaaactt
    17041 ttcatgggct tattgggagc ttgcttctgg atttggtata tacaatcaaa ttgaagggac
    17101 ttgggataga gaaatattaa gtgcattaat agaaaagagg tgattttatg aagaaaaatt
    17161 caaaaaagat acttataact ttaactatta ttactaatat agtatatata ttgtggagaa
    17221 ttttttatac agtacctaaa gaagaaggga tgtttgccct aatctgtgcc ataatacttc
    17281 tttttgtaga gataatgggc atgatggaaa tgtttgtgca ttattatggt atgtcaaata
    17341 ttgagtaccc tgaaaaacca atcataagtg aagaacttta tccacatgta gatgtattca
    17401 ttgcaacata taatgaatct gttgatttgg tgagaaaaac tgtaaatggg tgtattcata
    17461 tgcagtatcc agataagaaa aaggtacata tatacatatg tgatgatgga aatcgtgaag
    17521 aaatgtgtat tctagcagaa aaaatgggtg taaattacat aactagaact gaaagagaag
    17581 gagcaaaagc tggaaattta aataatgcaa tgcaacatac aaattcccct ttgattgcta
    17641 catttgatgc agatatgata ccaatgcatg actttttaat tgctacagta ccatactttt
    17701 tgaaaaatga gcaagctaaa aaagatggag aaaaagagga gtatgaaaag gttggttttg
    17761 tgcaaactcc acagagtttt tataatccag acttgtttca atttaatctg cactctgagc
    17821 gaaggattcc aaatgagcaa gattattttt acagagacat tcaattggct agaaatagga
    17881 caaattctgt aatttatggt ggtagtaata cagttatttc aagggaagca cttgaagaag
    17941 ttgatggatt ttatacttat tctattacag aagattttgc aacaggtatc ttaattcaaa
    18001 gtaaggggta tagatgttat gctattccag aagtacatgc atcaggttta tctccgacag
    18061 atttaaaaag tcttattaag caacgtgaaa gatgggcacg tggatgtata caaactggta
    18121 gacgtctaaa tattttgttt aggagaggtt taggtttttg gcagaaaata agttatattt
    18181 cttcaattac ttattggtat gcaagtataa aacgttttgt atatataatg gcacctattt
    18241 tattttctgt gtttaatgtg attgtagtaa aatgtacatt acttcaagta ttggtatttt
    18301 ggttgccaat gtatgtttta agtagtttat ctcttaaaat attttctcaa aatataagga
    18361 atgttagatg gaccaatata tatgaaacta taatgtttca gtccttaatg ccagcagtaa
    18421 tacttgaaac gtttgcaata tctaaaaata aattttcagt aacaaataag agtaaattag
    18481 aagaaaatag aatgtataag tttttacagg gaatacctta ttttatttac atggtcttat
    18541 ctatcatagg aattttaaaa atgtttgtag caatatttaa aatgagttcc ataacatatt
    18601 cagttgtatt attttggtta attggaaacc tttttaacct tgttatggct acattattta
    18661 tatcagggag acagcagtta agaaagtctg agcgttatat tgctgaaatt gattttaagt
    18721 taaagcaaaa ttcttatgtt ctttcttcaa aaacaattga tatatcagaa aatgggtttg
    18781 cgtttttgct agaaaatcca gaatatattt ccccagaaga agagtttgag gtagagttta
    18841 gagaaaaatc tggaaatgaa atgtatatag ctaatatgaa agcaaagatt gttaatgttg
    18901 tggaagtaaa ttcaaagtgg aaatatgcag cttatattac acatattgaa gatagtgaaa
    18961 tagataattg gatgtgtatt gttcacgata gaatacctac tttaccaatg acaatatcta
    19021 atcaactagg tttctttgat gatttgcaaa ttaatgtaaa aaaacgtatt gaaaaaacta
    19081 gaacattatc acgaagaagt ccaagaatca atatgaattt tcatatggat ataaaaaata
    19141 taggtaaatt aagaatagta aattttaatt atcaatatgt attattaaat tttgagaata
    19201 aaaatattta tcctaaagaa atagcattgg aaattagtga aggtattgta ctagaatgcg
    19261 atttatgtga gggtaaaatt gatgaaagag gtatcttata tagagtaaat aacattgaca
    19321 gcataatgca aaatttattt ttaagagatg aaatgatgga ttggatatta caaaataaga
    19381 aaattcttga ttcaaaacct aatgaaaaga aagaaaaaag tatagatgag tttgaaccca
    19441 tggaatatat ttaggagaga tgaaatgaag actttaaaag tgtttttttg ttctgcaaaa
    19501 tattttattt tagtgtttat tttttttata aatactactt ttataagttc agcaacaagt
    19561 gataaaattt tagatttgtc ctttaaaaag atagagactg acttaagttc taagattaca
    19621 tatgaagata caggtgtaaa aatagaaacg aacagttcta aaagtgataa gaaacgttat
    19681 ttatatattt accaaaatat gaaagaaaat tggagtatgt ataacaattt ttatattgaa
    19741 attcaaaata aaaataaaag ttctcagaaa ataaatttaa gcatacaaag taaaaatatg
    19801 cttgaattta gattaaaaga aggtagtgaa gtatttttag aagataaaaa tataatatat
    19861 tcagataaaa taaaagaagg atgcatagaa gtaccaggtg aatttgaagg caaaatttat
    19921 gtgaacttta atagtcttat aaatgagaaa agtaatgttg tgctagactc aagtatgctt
    19981 tcaaacattg ttagttgggg aattacattt attccatctg atgaagaaca taataatatt
    20041 attataaaaa agatatcttt attgtctgaa gagaaattaa gttttttaca taatattaaa
    20101 ataactggca atgaagaagt acaaatacca gtattgggtc aaggtataag tcagtatgag
    20161 gtattaggtc ttgaaagtga ttctaaaatt aagtattctc ttataggaaa acaagataat
    20221 ttaagtattt ctcaaaaagg taaattaaca ttaaataata aatccaaacc tggacaaatt
    20281 attttacaag ttgacgttga tgataagttt aaaattggaa agaaaataac attaactgaa
    20341 tcttggagta ttaataaaaa agataaggat ggtgttccat atacattagt atctcctgag
    20401 caatcaccaa cagtacaaga tatgaaaaaa ataaacttta tgaataatat cataacattt
    20461 gttcgaattt tatttgtatc tctagtaata atatgctttg gaatatattt atattggaaa
    20521 aaatgttcaa aaactaagta aagagaggag gttagattgt gttattttca agtttaattt
    20581 ttttatttta ttttttacct ataactttgg ttttatatta tgtatttagg tttaaccgaa
    20641 cgatacagaa catgatattg cttgctgtta gtttattttt ttatgcttgg ggagagccaa
    20701 aatttgttgt tatcatgata gtttccataa taatgaacta tatatttggt ttactggtag
    20761 atagatatag ggaaagtaaa ataaaagtaa aagttttttt agttttgatg tgtgtataca
    20821 atataggtgt tttatttata tttaaatatc tagcttttgc gctaagaaat attagtgaac
    20881 ttattaatac tgaactaact atacctaata ttattttacc tataggaatt tcatttttta
    20941 catttcaagg aatgtcttat gttatagatg tatatcgtag acatggagaa gtccaaaaga
    21001 atccttttta tgtgggactg tatatagcat ttttcccaca attaatagca ggtcctatag
    21061 ttagatatga gagtgtggca gaacaaattc tcaatagaaa agaaacttgg aataaatttt
    21121 ctattggtac ttgtaggttt ataacaggtc taggtaaaaa agtattaatt tcaaataaca
    21181 tggctatagt agcagactat atttacacta tgaatagtca aggagaaata gctgcatcac
    21241 ttgcatggct tggttcaata gcctatacta tgcaaatatt ctttgatttt tctgcttatt
    21301 cagatatggc tataggttta ggtcttatgt ttggttttaa atttgaagag aactttaatt
    21361 atccatatat atcaaaatca attagtgagt tttggagaag atggcacatt tctttgggaa
    21421 tgtggtttaa gagctatata tactttccgc ttggaggttc tagagtagca aataaagata
    21481 ttatgattag aaatatgttt atagtgtggt tatttactgg aatatggcat ggagcagaat
    21541 ggacatttgt aatttggggg attttaaact ttgttttcct aattatagag cgatttataa
    21601 tgtttgaaaa gattgaaaat cacaatttta taaaacatat ttatgcgtta ttagtagtta
    21661 attttgggtg ggtattgttt aggtcaccta atttaaaaga agcatataat tatttcaaag
    21721 ctatgcttgg aggcaatgga gttatatgga gtgattatac atatatgttt ttaaaagaat
    21781 actgggtttt ctttatattt gcatttattt ttagtgtgcc tattgcaaag aaaatcaata
    21841 agtttgttgt tgaacaagtt aagtatagta tgatatttaa tgtattttat ccaatctcag
    21901 ctattttatt gttctttatt tctgtgacat atttagtaac tggaagctat aatccattta
    21961 tttattttaa tttttagttg aggaggaaaa gtatgaatag attttttaaa gtaagattaa
    22021 taactgcaat tatgttctta gttgtcttat tcgctttctc tatatttaat atttgttatt
    22081 atggaaaaga tatgatacag gagataaaaa attcagttgc tgaaaaaagt agtttaaaag
    22141 atacaatatc atctattgat aatacagtaa atgacaaagt aatatataaa aatacgttca
    22201 ttgaaactta tggctactta caaaaattaa tgggtaaaaa tgagttttca aaatttagtt
    22261 ctgtaaaaga tacttctgga aagatgcatt atacatattt tgctaaagct ccaaatccaa
    22321 ttggtgttat atcagataga gtaagaaaat tttctgaaga aatggaaaag caaaacacta
    22381 aattggttta cttaatgact ccagataagt atataaaagg agtgacaaaa tttccaaaag
    22441 ggatacctta ttcttatagc aatgagacag cagataattt tttaaatcaa ctaaaaaagt
    22501 ataatgtgga ctatattgat tttagagaaa atattttaaa gagtggtatt ccaaaagatg
    22561 atttattttt taaaacagac catcactgga aagtagaaac ttctttttgg gcatttgggg
    22621 aattaattga gcaacttaat aaaaaataca atataaattt agatgaaaat cattattata
    22681 gagataaaga aaattataat tcaattgtat atcctaagtc atttcttggt tctatgggaa
    22741 gaaagtctgg tattttatat ggtggtatag atgattttgc attaatttat cctaaattta
    22801 agactaatta tacttattat acagattcta aatttcaaaa atttgaatta aaaggaaggt
    22861 ttgaagagag tttgatatta tcatatcctt ttaacgcaga ccttaattta atggatggtc
    22921 aatcagataa atattctaca tatttattgg ggaatagacc attagttaaa ataaaaaata
    22981 tagaaaatcc agatggatta aaagtgctat ttgttaaaga ttctctaatt gtaccaacag
    23041 cagcattttt ttcctctgtt tgttcatcta tagatatgat agaccctaga tactatgatg
    23101 gagatatact agaatatgca aaatctcatg actatgactt tgtttttata tctatatatc
    23161 cccaaaatct tacaaaagaa ttttttccgt tttgtgagta aatttctaaa aaagttttct
    23221 gataaaataa atggctaact ggtaaaaagt tagccattta ttttgagtgt tattctaaga
    23281 aatatttttt ttactaaata cttctttatc tatttttcca agtgattttc ctacagtaat
    23341 tgatgatacc atagcaccat taacatttat catagtacgt cccatatcta gtatagggtc
    23401 tattgcaagt ataccaccaa ctaatggaaa ataagaacca agaccaactc cagagataac
    23461 aactgaaacg gccattgtag cagttcctgg aagaccagct attccaaacg aactaattgt
    23521 tataacaatt aacaacataa cataaaagct catatccatg tttactccag ccatattggc
    23581 aagtgttaca gccattaaag caggatatat acctgcacaa ccattcatac ccatatttgc
    23641 acctaaactt gctgtaaagc ttgatacacc ctcatcaact ccgtgatttt gtactagact
    23701 ttctatcgtt acaggcaatg ttcctaaact agaacgtgaa gtaaatgcca gaagtaaagc
    23761 ttcagttgaa ttttttatat aagtaatggg atttagacca tttaaagtta taaaaattaa
    23821 atgtataata aataatattg caactgatat ataaagagct aatataaact gtaaaacaga
    23881 tactattgaa ctaatacctt gtgaagttat tgtatttgca agcagagcaa ccacagcata
    23941 aggcataaat ttaataacag tcatagacac acttacaatt attttgtaag atgcttctat
    24001 aaaatctata aatggtttta ttgtctcaaa atgtttttta cttaatctct ttattgaggt
    24061 agctataaat gtagcaaata ttattgtagc tacaatattt ccatttgcca tagccattac
    24121 aggattagat ggtagtaatc ctcttaaagt atccacaaga gagtttattt ctttaagttc
    24181 ttgattttca actaaagtag gcatattagc tcctacacct aacttcatta tatttgcaac
    24241 gataattcca acaattgcag ctatagcagt agtagcaaga agcataccta aagatttaaa
    24301 tgtcagagtt ccaagattgt tatctttcat atttataatt acttttataa tggataagaa
    24361 aactaaaggt actactaaca tttttaataa gtccataaat ccagaaccaa ataggctata
    24421 ccacttactt acttcttgta gccaagtgac ttgagttgta tcattaggaa aaccagcaaa
    24481 agcttgtatt atgattccca atatgagtcc tagtactgta gcatatattg ttctcaatga
    24541 aaattttatt tttttctttt caaattgtct aacaataaag aacgtaccta gaagtaatat
    24601 tatgaaaaaa attgttttaa aatctgtaat cataagaaat tgtgataaaa atgaactttc
    24661 caatattttt ctccttttat ttaaaaataa atttttctaa gtttaaatga tatcaatata
    24721 ttaaaaaaat gtcaatatta tatcacaatt tacttaaata gagtaaaaca agttgatttt
    24781 gaaaaatgtg attaagtaca gaaaaatagg gtataataaa tgtttaaaga atttgaattg
    24841 tggtaagaaa ataaaaaata gcttttataa gatttgattt caaattaaaa tatgttaaat
    24901 aaataactaa aaattattat aaaaaatgtt ttcatagaat atatatcaaa tgaaaagctt
    24961 aaaataagtg aagaaattaa ctagacatca aaggagagat aaaatgagag taataataat
    25021 tggtggtgtt gcagctggta tgagtgctgc agcaaaatta aaaagaataa aacctgagta
    25081 tgaagttgtt gtttatgaaa aaactgaaat agtatctttt ggtgcttgtg gattaccata
    25141 ctttgttggt ggatttttta atgatgctga tgaattatta gcaagaacac cagagaaact
    25201 tagagaagct ggaattgatt taaatatatt tagagaagtc gttgaggttg atagtgaatc
    25261 taagaaaata aaagtaaaaa acataaaaac agatgaaata tatgaagatt actatgataa
    25321 attgatgata gcaactggag caagaagtat tatgcctcct ataaaaaaca taaaattgaa
    25381 gaatgtttct acattaaaaa gtttatatga tggagaatat ctaaaaaaac ttttaagtaa
    25441 tgaagataat aaaagagtga caataatagg agctggtttt atagggttag aagcagttga
    25501 ggcatgtaag aaattaggta aagatgtaga tgtaattcag ttagaagata gaatattgcc
    25561 acaagtattt gataaggaaa tgacggatgt attagaagaa gaaataaata gacataatgt
    25621 taatttgcac ttagatgaaa tggttgtaga actttgtgga gaagataaag tagaaaaagt
    25681 tataacaaac aaaggggaaa tagatacaga tgtagtaata attgctactg gcgtgagacc
    25741 taataccgag tttttgtcaa atactaatat aaaaatgcta aaaaatggag ctatagtagt
    25801 tgatgagtat ggaagaactt ctgtagaaga tatatactct gctggagatt gtgcaactat
    25861 aaagaatata gtaagtaatg aaaatgtata tgttccttta gctactggag ctaataaatt
    25921 gggtaggata gtaggagaaa acctagcagg aagagaagta tcttatcaag gttcactatc
    25981 ttcaagctgt ataaaaatta tggatatgga ggcagcatca actggaatta cagaaaagca
    26041 agctaaagat ttaggcataa atgtcaaatc taaatttatt tctgattata atcaaactca
    26101 ttattatcca ggaagaaata aaatatatgt aaagcttatt tatgatgcag atacaaaagt
    26161 tattttaggc ggacaagtgg ctgggtttaa ggatgctgtc caaagagcaa atgtattagc
    26221 agctgctatc tttggaaaaa tgaccacaaa tcaacttgga atgttagatt tatgttatgc
    26281 tccaccattt gcaagaacat gggatgtttt aaatgtagct ggaaatgtat ctaaataata
    26341 tttagattat agctaatata gttgacaagc aattaaggga atgaatttac ctaaactatt
    26401 tttatcatgg taaaattcat tcctaaattt ttattccaaa tttttattcc aaatttttag
    26461 aaataaggat tccattaaat tattcatcaa aatttaaacg caagcttaat ctatcttctc
    26521 caagaatagt attttcaaaa acattagtag cattttctaa atacatacta ggtatgtcta
    26581 aagaaggact aaaatgagtc agtaaaagtt gtttgacatt tccaagtttt gcaagattag
    26641 cagcttctct aaaagtcata tgtttgtttc taacagcttt tgatatatct aaatcatcac
    26701 catacatggc ttcacatata aataaatcac tatcttttat gaaatctggt attgattcta
    26761 taggtcttgt atcggttgta agacttatct taactccctt tctcaattct cctaagacca
    26821 tatctggagt gtattgtttt gaatctaaaa ctatattttg accttcttgg agtttgttcc
    26881 ataatatttt aggaacttcg tttttagttg ccttatctat atcaaattta gggtttcttc
    26941 taaaattaaa actgtatcct aaacactcta tagagtgttc taaactgatt gttgaaattt
    27001 ctaaatttct taaaacttta ttatctaaag aaaaattgcc ttgagggttt tctataattt
    27061 ttaaagtgta tggtacatat tctactaaat ttctcataga acgtatacaa tcgactattc
    27121 caactggacc aactatagtt aaatcacttg tacgaccact attcccaatt gttgataaaa
    27181 gtcctaaaag tccaaatata tggtcaccat gtaaatgggt tatacaaatc aagtctatat
    27241 ctttaaagcc acattttttt agcttcatag atacctgagt accttcacca cagtcaatta
    27301 gtatttttct acctttatag tttataaata cagaggatag aaatctgttt ggcataggta
    27361 catttccacc acatccaagt aaagttaaat ctatcatttt ttcccctttc taaaattaac
    27421 acaaatctgt tgtttgtttt tattatgata tcctattata attattttaa cattaaatat
    27481 aacaataaat gtgtatttga gtcaagaaat attgtcaaat aaagttttta tatagaaatg
    27541 tataaaaatt tggaaaacaa aaagtgaaaa ttatatttag gagcatttaa aggaggaaaa
    27601 tttaatgaaa gtattaaaga aaattactat tttgtcattg attacattaa ccttagttgg
    27661 ttgtagtaac ggagaagata aaaaagtggt tgaaggttct aagaaaattc aaaattctaa
    27721 aaaagatgaa cagcctataa tagtacataa agatgcaaat atattgaaag ataggtatga
    27781 gccaccaaaa ggatttaaaa gagttgatgt agaaaaaggt agttttgaat catttcttag
    27841 gaatactaag ctaaaaaatt atggagagaa agtaaagtat tatgatggaa gaactaagga
    27901 atcaaaaggt atttatgata gtgtatttga tgttgatatt ggcaatagag atttacatca
    27961 atgtgcagat gcaattatgc ttatgagagc agaatacttg tatcagaata aactatatga
    28021 tgaaataagt tttgattttg ttgatggttt taaggcgaag tattcaaaat ggacacaagg
    28081 atatagaatt tcagtaaaag atagtggttc aagctggtat aaagcaactg aatattcaac
    28141 atcttatgag agttttagaa agtttatgga tatagtgttt gcatattcag gaacgttatc
    28201 tcttgaaaaa gaattggagc ctgtaaaagt tgaggatatg aaaataggag atgtgtttat
    28261 agttggtgga agtccaggac atgcaagtat aattatggat atggcagaaa atgaaaagac
    28321 tggtgaaaag gtatttatga tagcccaaag ctatatgcct gcacaacaaa cgcaacttct
    28381 tattaatcgt aaaaatccaa atttgagtcc ttggtatagt ttagattttg aaggtgattt
    28441 gacaatacct caatggactt ttaaaagaga ccagttgaaa agattttaaa ataataattt
    28501 tatataataa aagaaaaata tagatgtgaa aaaatgtaat ta
//
LOCUS       DAEPXW010000049        27751 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.050, whole genome shotgun sequence.
ACCESSION   DAEPXW010000049 DAEPXW010000000
VERSION     DAEPXW010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27751
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.050"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            120..749
                     /locus_tag="KRM55_002119"
     CDS             120..749
                     /locus_tag="KRM55_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594359.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNVMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            750..1532
                     /locus_tag="KRM55_002120"
     CDS             750..1532
                     /locus_tag="KRM55_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1594360.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTFKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            1525..2403
                     /locus_tag="KRM55_002121"
     CDS             1525..2403
                     /locus_tag="KRM55_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594361.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            2436..3395
                     /locus_tag="KRM55_002122"
     CDS             2436..3395
                     /locus_tag="KRM55_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1594362.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3709..4401
                     /locus_tag="KRM55_002123"
     CDS             3709..4401
                     /locus_tag="KRM55_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594363.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            4411..5415
                     /locus_tag="KRM55_002124"
     CDS             4411..5415
                     /locus_tag="KRM55_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1594364.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            5683..6534
                     /locus_tag="KRM55_002125"
     CDS             5683..6534
                     /locus_tag="KRM55_002125"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH1594365.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            6638..7384
                     /locus_tag="KRM55_002126"
     CDS             6638..7384
                     /locus_tag="KRM55_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594366.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            7384..9300
                     /locus_tag="KRM55_002127"
     CDS             7384..9300
                     /locus_tag="KRM55_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1594367.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIIKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            9582..10499
                     /locus_tag="KRM55_002128"
     CDS             9582..10499
                     /locus_tag="KRM55_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH1594368.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILSEIEKMKKIY"
     gene            10577..11314
                     /gene="cas6"
                     /locus_tag="KRM55_002129"
     CDS             10577..11314
                     /gene="cas6"
                     /locus_tag="KRM55_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH1594369.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENVGFKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            11320..13197
                     /gene="cas8a1"
                     /locus_tag="KRM55_002130"
     CDS             11320..13197
                     /gene="cas8a1"
                     /locus_tag="KRM55_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HBH1594370.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIDKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKEYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTCINELFERNNSLKVQKSESSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNVLDLLLKNRDLKHITNNILRNKVKNDMESNNKSNISGIDCFRVVQLRVLINSYKKG
                     VYKMDSKNLEKNDEKLKIIYYLGCDIHDYFVNKNSKNKIDGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQIPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            13199..14113
                     /gene="cas7i"
                     /locus_tag="KRM55_002131"
     CDS             13199..14113
                     /gene="cas7i"
                     /locus_tag="KRM55_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBH1594371.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNMYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGFADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGEIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            14115..14816
                     /gene="cas5b"
                     /locus_tag="KRM55_002132"
     CDS             14115..14816
                     /gene="cas5b"
                     /locus_tag="KRM55_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBH1594372.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            14827..17148
                     /locus_tag="KRM55_002133"
     CDS             14827..17148
                     /locus_tag="KRM55_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH1594373.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEIVECNSNMN
                     IGEYTEKHLVKEFGSLREVQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIIGVGEANDTFLGLLHSTAIDYLEESNQENSNEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLADLTCNTEKIRHCVSIVENSIDENLGKII
                     QNGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIYENKHTKQIFGKGVLISNEIDQFI"
     gene            17163..17714
                     /gene="cas4"
                     /locus_tag="KRM55_002134"
     CDS             17163..17714
                     /gene="cas4"
                     /locus_tag="KRM55_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HBH1594374.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEILIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            17717..18697
                     /gene="cas1b"
                     /locus_tag="KRM55_002135"
     CDS             17717..18697
                     /gene="cas1b"
                     /locus_tag="KRM55_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HBH1594375.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            18700..18966
                     /gene="cas2"
                     /locus_tag="KRM55_002136"
     CDS             18700..18966
                     /gene="cas2"
                     /locus_tag="KRM55_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HBH1594376.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   19150..20495
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=19150..19178
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            20685..21113
                     /locus_tag="KRM55_002137"
     CDS             20685..21113
                     /locus_tag="KRM55_002137"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBH1594377.1"
                     /translation="MIKKLNSKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLNL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(21568..22338)
                     /locus_tag="KRM55_002138"
     CDS             complement(21568..22338)
                     /locus_tag="KRM55_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594378.1"
                     /translation="MKVNENNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLL
                     FFAVKYNYFNIVCFAIENNYLNLNMPSKNKKYTNIMEHLLDTSKQSEDKKIYNYLLSL
                     NKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKF
                     SSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGIIAK
                     KKMNFDENTEKFKDVSTSYCCGNCDSEISLSQREHFKI"
     gene            22662..23207
                     /locus_tag="KRM55_002139"
     CDS             22662..23207
                     /locus_tag="KRM55_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBH1594379.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            23239..24375
                     /locus_tag="KRM55_002140"
     CDS             23239..24375
                     /locus_tag="KRM55_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBH1594380.1"
                     /translation="MEEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            24379..25770
                     /locus_tag="KRM55_002141"
     CDS             24379..25770
                     /locus_tag="KRM55_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBH1594381.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRIIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            25846..26721
                     /gene="dpsA"
                     /locus_tag="KRM55_002142"
     CDS             25846..26721
                     /gene="dpsA"
                     /locus_tag="KRM55_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBH1594382.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYTLDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            26724..27314
                     /locus_tag="KRM55_002143"
     CDS             26724..27314
                     /locus_tag="KRM55_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBH1594383.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(27521..27721)
                     /locus_tag="KRM55_002144"
     CDS             complement(27521..27721)
                     /locus_tag="KRM55_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594384.1"
                     /translation="MKKLKTISIFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT        11180 a         2645 c         4657 g         9269 t
ORIGIN      
        1 ttaaaaaatg tagataaaaa ttgttttatt aagaaaaaat taatatattg acaaaattta
       61 agtgctcatt taaactatta attgataata atattcaata ttaaataata ggaggcgtta
      121 tgaataaata tcttctaata aatccagtgg cagaaagaat gtatggagaa aagtttcacc
      181 ttattaaagc aaatttgata aaaaaggggt acataatagc agaatgtgaa ccacagttag
      241 aatatgtaaa aaagcagtac aaagagtata caaaaaagac tgaaaataca atgttggatt
      301 gtagatgtcc agaaagtata agtcttttaa aaagaaataa tttgataaat gattttgaag
      361 tacctatgat agaaccaata ttagtaagga cttgtagggt tttatacgat aaatatataa
      421 aaagtaaaga tgatatgttg gtagtaacct gtccatgtac acaattaaga gactttgcaa
      481 gtgaaaagtt taaggataag ggtaatgtta tgttttatac atggaaagag tttgctgaac
      541 aagaaggtgt aaaatcactt ggaaaaatag atgaatcacc aattccatta ggatatttca
      601 aagatacttt tgaaaaagtt cttgaagtat caagtgaaga cgaaatatta agtgaaatac
      661 aaaaaataag aaatggcttt gaagataagt atgacatagt agaaatgttt tattgtaaag
      721 atggttgtaa taatggagat ggtttgtaaa tggtcaataa atttaataat aagtttttaa
      781 ggctagtaaa gagtgttctg atatttttta taattctttt attatggaaa attacaaatt
      841 atcttggtat ttggagtgat tatatattac catcacctga aaaggtatat agtacatttt
      901 taaatatgat aagtgatggt tcaatattta ttaatgtata tgcaagtatg aaaagagttt
      961 tgataggttt tgcaataagt actgctatag gtgtgccttt agggatattc tttggaattt
     1021 atagtggagt atacgaatac tttaaatctc taataaattt tttaaggaat acacctcccc
     1081 ttgctttaat accaatgctt atattatggt ttggtatagg agaggaatca aaaattataa
     1141 ttatagtttt agcatccttt ttcccaatct ttacaagcac atttaaaggg attaaaaatt
     1201 gtgactcaaa actgattgaa gtgggtagag tatttgagtt ttcaaagctt cagataatat
     1261 ttaaaataat aataccaaat gccattcttg atattgctgt tgggttaaag ttagctcttg
     1321 gatatagctt tagagcaatt attggggcag aacttgtagc agcttcatct ggtcttggat
     1381 acttgatatc tgatggaaaa gaaatgtcta gaacagatgt tgttattgta ggtataatcg
     1441 taattggact tttaggaata attacagatt acatattttc gattattgtg aagaaggtaa
     1501 gtaagggaaa gatggtggaa gcatatgaat aatttagtat gtgactctgg atatataatt
     1561 agaaatttat ataaaagtta taaagttgac aatgaagaac atgtagttct tagtgatatc
     1621 tctttaaaca tagatagaaa ccatataaca gtaattttag gtgaaagtgg ttgtggaaag
     1681 actaccttgc ttagagcaat tgcatcactt gaaggtataa atagtggtga aattaggttt
     1741 attaatgata ataaagagta tagacctaat gttggttttg tttttcagga gagcagatta
     1801 atgccttggt taaacgtaag tgaaaatata gcttttcata atcaaagaaa aaatactatt
     1861 ttaaacaagg tgcttagaaa atttaaacac aataaaagaa ttagcagtaa aattataaat
     1921 gataatttta gaagcttaga aacaaatgat aatttgaaca aatcaaataa atataatagg
     1981 aaaagtaata ttgatgtaga aaaatatctt aagatgatga acttgcagaa atttaaaaac
     2041 tcttatccaa atgaattgtc aggaggtatg gcgcagagag taagcatagc tagagctctt
     2101 tctttcaatc cagatatgtt gcttatggac gagccttttt cggcattaga ttattttaca
     2161 aggattgata tgcaaaatga agttataaga atacataagt caactaataa aggcgtgata
     2221 tttgtaactc atgatattga tgaagcgtta aagataggca agaaaatagt tgttttcaca
     2281 gacgaaagaa aagtaaaaga atttaatata gaagatggtt ataatagaga tttaacttca
     2341 gattactata ttaaattaaa aaaagatatt ctaatgacaa tgaaatcaaa taaaggcatt
     2401 taaagaaatt aataatattt taaggagtaa agtaaatgaa attaaaaaag ctattgatag
     2461 gtataacgat attaacactt gcaacagcat ctttagctgg atgtgctaaa aaaaataatg
     2521 gagaaaaact ttcagaaata aatttaactt atgtaaaatc accattaaat gttccttcta
     2581 taattcaaaa acaggatgat ttatttggaa aggaatttaa aaaggataat ataaaagtta
     2641 acttccacga aattactaca ggtccagagc aaacacaagc tttagctgct ggagaaatag
     2701 acttcttaca tgcactaggt ggtacatcag ctttaatagc tgcatctaat ggagtagagt
     2761 taaagatatt aaacacttat agcaggtcac caaaaggatt tatgattttg actaataata
     2821 attcaataaa atcagcagca gatttagtag gtaagaaggt ggcaggccca aaagggacta
     2881 tattacatca ggtattgatt tcagcacttg ataaagaagg attaagtatg gatgatgtgg
     2941 aatttgttaa tatgggtatt ccagaggcat cagcagctct ttctgatggc agcgtagatg
     3001 ctgcattgat tgctggtcca gcagctctta aagctatgaa gtcaggtagt aaacttgtag
     3061 caaatggtga aggtttagta gatggtataa tagtaactgc tgttagcaca gactttgcag
     3121 agaaacatcc agaaatagtt gaaagattta tgaaggttga aaaggaaact ttagaatatg
     3181 taaataataa ttttgatgaa gctatggaaa aagtagctaa agaagttgat ttaagtcttg
     3241 aagaaactaa agaattatat gcttggtatg attttagttt agatataaca gataaagaca
     3301 tatcttcgct tgaagataca caagacttct taataaaaaa taagttacaa gagaaaaaag
     3361 tgaacataaa agaattaatc tataatgcta agtagaaact atgataaaat aatactaagt
     3421 aagaaatata ataaaagttt aagttacctt attaaggtaa ctttttctat tttgaattag
     3481 taatttcaat ttattttaga atgattagtt gataataatg attaattaat cataaaaaga
     3541 tactttttta tagagtttta ttaagatgtc taataatatg gttatactta tgaagtcagt
     3601 aattgtgaaa ttagcaatat gattaaattt atatattgta aaaagattat aatatattaa
     3661 aattggactg ttatatgatg agtaaatagg tatattagga ggaattatat gagttataaa
     3721 gtatatattg tggaagatga tatatcaata agtacattac ttaaagatta tattgagaaa
     3781 tatggatttg aagtgattgt tgaagagaac tttgatgata taatgattac atttgaaagt
     3841 tttaagccac acttagttct attagatgta aatttaccta aatttgatgg tttctactgg
     3901 tgtagatgta ttaggcaaca gtcgaattta cctataattt ttatatcagc tagagatggt
     3961 aatgtagacc aaattagagc tttagaaagt ggagcagatg attatataac aaaacctttt
     4021 tactatgatg tagtaatggc aaaaataaag agtcatataa gaagggtata tggtgaatat
     4081 tcacctaaaa tagacgaaag aatagtggag ctagatggat taaagtttta tccagagagg
     4141 ttagaactag aattaaatgg tgagaatcta attataacta aaaaagaagg tatactgatt
     4201 gaatgtctta tcaagagata cccaaaagta gtaagtagag attatctttt agaaaagata
     4261 tgggatgata ttgagtttgt agaggaaaat actttaaatg taaatgttag caggataagg
     4321 aaaagatttg aggaattagg tatagataat gctgttcaga ctgtccgagg gttaggatat
     4381 aaattaaata agaattggta aggagaaagt atgaagttat ttttaaaaga ttataaaggt
     4441 tatattttta tatattatat aggcatagtt atgacaatta tttactgtaa tcttatgaag
     4501 tttattagtt ttggagagag tttatatatt cttttattta gttcttttat attgttatgt
     4561 tttttaatat ataagtatta taaaaataga gaagtatata atctgtttga aaaaggagta
     4621 cattctttgg aggagtcatt tttgtattta ggaagctcat tcttggggag aaatatatca
     4681 gttattttaa aacaacaaca taaattgtat caatcaatga tacaagagca taaaaagata
     4741 catagtgaac atttaacttt catcaaccaa tggattcatc agatgaaaac accaatatca
     4801 gttataagcc ttcagcttca agattatgag ggagaagaag taactgaaaa tataagaaaa
     4861 gaaatagata gattaaataa agggttagat atggctatgc attttgcaag ggcagataat
     4921 tttcagaaag attttatagt tgaaaaagcc aaattaaatg aaattgtatc tagtattgta
     4981 aatgaagaaa aaaggttatt tataaaaagt ggaatgattc ctaagattca agtagacaaa
     5041 tttacttatg tttatacaga tgtaaaatgg atgaaattta taataggtca attaattaca
     5101 aatggagtga aatattctaa agattatagt aactacctaa ctataaaatc tgaagaaaat
     5161 aataaatatg taattttaag tataatagat gaaggaattg gaattgtttc taaagattta
     5221 aaaagggtat ttgacccatt ttttacagga gaaaatggtc gtaagtttgg agaatctaca
     5281 ggtatgggtc tttatctagt aaaaaaggta tgtgatgatt taggtcataa agtaagtata
     5341 aaatcagaag taggaaaagg tacagaagtt tcaatctact ttaataaaga tgtaaatagt
     5401 ttaataaagg tgtaaatagt ttgataaaga tgtaaattat ctgttacaat agggttttta
     5461 gttaattgta cttttttatt atacaattta ttaaatgaaa tattcatagt taaataatca
     5521 aaatttaaga gagtttattt gcaaacctta catagatgta aggtttgtgt aatgtttgca
     5581 gatagttaaa ttttctaatc taaattacaa ttaatataag aaataacata agagaaataa
     5641 cataaaaaaa gaaattttgt aaaaaaggaa ggatgtttat tgatgagttt agatgttatt
     5701 tttatattga aatcagtcat aatagctata gtagaggggc ttacagaatt tattccagtt
     5761 tcatctacag gtcatatgat tttggttggt aatttaatag attttaaggg gcaatttgct
     5821 gaaatgtttg aggttgtaat acaacttggg gctatattag cagtagtagt actttattgg
     5881 aaaaagataa aagatagcgt tatagaattt tttaaattta tatttactgg cggaaaagaa
     5941 ggaaagattg gttttagatt tggaatgaat gtaattatag gttgtatacc atttgcgatt
     6001 ataggagttc tattttacga taatataaaa tcattgttta atttacaatc tgtaattata
     6061 ggatttatag tgggtgggat tttattatta gtagtagaaa ctttgtttag aaaaaagaat
     6121 cattccacag ataatataga taaaattact ccaatacaag ctttaaaggt tgggacatta
     6181 caagttttgt ctgcatggcc aggtatgtca aggagtgcat ctactattat gggtggatgg
     6241 atagcaggac ttaattctcc tacagcagct gagttttctt tctttttagc agtaccagct
     6301 atggtggctt cttcaggaaa agatttattt gaatttgatt attcaataat gacaccaaca
     6361 ttgtggattg ctttggtagt tgggtttata gtagctttta ttgtatcaat aatagttatg
     6421 gaaaaattcg tgaatttttt aaagaaaaaa ccaatgagag tgtttgctgt atacagaata
     6481 atcatgggtg tagtacttgc agtattagct tttactaaca taattagtgt atagaaaaaa
     6541 tagatttatt atctataaaa attaaactaa gataaattat aattaacaat tatatatatg
     6601 ttatttcaaa aattaaatta ggaaggatag ttaaataatg aaaattttaa ctgtaaataa
     6661 tttaagtaaa gtatatggta aaaaaataat tttcaacgca ttaaatgaca taaattttag
     6721 tatagaagat ggagaatttg taggaattat gggtccatct ggtagtggaa aaactactct
     6781 tttaaatatg atttctacta ttgacaagcc aactacagga actatggaat taaagggcaa
     6841 gaatccttta ttgttaagag gtgaggaact tgcattattt agaagaagag agttaggttt
     6901 tgtatttcag gattttaatt tattggatac attaactata ggagaaaata tagtattgcc
     6961 attgacatta gataaggtca gtgtaaaaga gcaagatgag agattgaatg aagtatctac
     7021 aatattaggt ataaaagatt tattaggaaa aagaactttt gaagtctcag gtggtcaagc
     7081 tcagaggact gctattgcta gagcattgat taacaatcca tcaatacttt tagcagatga
     7141 accaacaggt aatttagatt caaagtcatc aaaggttgta atggagctat ttcaaaagat
     7201 aaataaagaa aataaagtta ctactatgat ggtaactcat gacccattag cagcgagcta
     7261 ctgtagtaga atcttattca taaaagatgg gtctatatat aatgaaatat ataagggtag
     7321 tagtagagag cagttttatc aagagataat ggatgtactt acattattgg gaggcgataa
     7381 ctaatgaata taaaacagtt tgctattaac aatatttcaa gaaatattaa agcgtattta
     7441 ggatacttag caagtattgt tatatcatct tcactgctat tttcttttat tatgtttaca
     7501 agtcatccag atttagatgt atctcaattt cctgattatt taaaagaagg tctcaagatg
     7561 agtaagataa ttgcatatct attcttattc ttctttgtgt tttattcagt tagtgtgttt
     7621 cttaaaagta gatataaaga atttggaata ctttatatta caggtatatc aaaacgccaa
     7681 gtaatgaaat taatctttat agaaaatatg ataataaata tagtatcttc tgtaattgga
     7741 ataataatag gcttaatctt tgcaaagata tttttagtgg ttatgtctac ttttttagaa
     7801 ttatcaccat taaaattcta tataccattt aatgcgatat tgtctacttt aatctatttt
     7861 atgattttag ctgtattaac atcaatattt acttctttta tagttaaaga aaatcaggtg
     7921 ttgaagttac ttaaaggtac aaaaactcca aaaccagagc ctaaaacatc actaatgctt
     7981 gctatattaa gtatttgttt gtttataata gcgtattata atgctattac ctcaactgac
     8041 caatatacaa catatctgcg cttagttcca gttacatccc ttactatagt agcaacttac
     8101 ttgttctttt ctcaatttag tgtatttttt atgaagaagc taaaattaaa caagagattt
     8161 tatagaaaaa atacaaatat gctttggatt tcgaacttga tttataaggt aaaggataat
     8221 gctagaatat ttttcttgat aactataact tctgcagtag catttactgc tataggtaca
     8281 gtttattcct tttggaaaga tgtagagcgt caaattaatt taatatatcc taacacaata
     8341 tattattcaa caatgacatt gcataatgac cctaaaaagc ctgatagcaa agaaaaagac
     8401 aaggaaagaa tgatgtttat agaaaataat ctaaaaaaag agaatgtaga ctatacaagg
     8461 actaatggtg aatttaaaac tgtatttccc aagaaaagtg attttaatgt cagaattatt
     8521 aaagaatcta agtacttaga aattacagaa actatagggg ttaagcctat aagttttgaa
     8581 gataatgaat gtatatcatt attatcatca agtttaccag gaaataataa cgtcaaagaa
     8641 aatattattg tagggaatag aggtttaaag gtggcaaaac aagtggaaga atgtgttatg
     8701 ccagcatatt acaaaaatat gtatgtggta aaggataatt tttatgatag tatagaatca
     8761 aaatttatag tggatagatt tactgcattt gaagtagagg attcaagtaa aactatagag
     8821 atatgcagag aatttgaaaa taaatttaat aatgagtcag ggatgcaacc atatttgttt
     8881 ttctctaaag aattaatgat aggaactggg aaattaatgt attctacatt tatattttta
     8941 gcaatattta taggtttaat tttctttgtt actacaagta gttttttata taataaattt
     9001 tatatggatt gccaagttga taagaaaaag tatgagcaat taaataaatt ggggatgaca
     9061 tataatgaga ttaaaaaagc ttcaacaatt gagattggaa tagtattttt gtttccttat
     9121 gtagtggctg ttatacattc aatatttgca cttactgcac ttaaaaattc ttttgatata
     9181 gaagtagcat catcagctgt tttggtaatg ggaagcttgt tcttggttca aatagtttat
     9241 tttttaattg taagaaataa ttatttaaaa gagataaggt taaatttagt caatttttag
     9301 ttactattat taaatgataa taaaaagggt ttaaaattaa ttaatattac tggaattata
     9361 gatgtttatt ttttcagtaa tattttttat tgtattaact attaaaattt tgtacaaata
     9421 taaaatataa tatggtaaat gtcaaaatta taaaaaaatt ctacttatat aaaatataaa
     9481 gaggttatat gtacatatgt gtagaaataa ataataaaaa tatcaattaa tgttattagg
     9541 ggggggggtt actcattagt aaattagcta atacacttag aatgatgata ttaattcaaa
     9601 gcagaggcaa aatgaaatgc aaagaattat cagaagagtt ggaagtaagt gaaaggcaaa
     9661 taaaaagtta caagatgtat ttagagcaag ctggtatatt tataaattca acacctggga
     9721 tttatggtgg ttatgaaata gataaatgta atagcatctc attaattaaa ttattagata
     9781 gtgaagtttc aattctagat atgataaatt cacagttaga gtataataat gatatttaca
     9841 aaaatgaatt taataatatt gtagaaaaaa taaaagcagt attaaataca ggagaaaaaa
     9901 gcgatacata tatggattat tttacagttc aagcacaacg taattgtgat tatgagtctg
     9961 aaaaaaataa gtgtaatgaa ataattagag catataccac aaaacacaaa ttttggatag
    10021 aatattattc attaaattca ggaaatagtg aaagaattgt tcatccatat ggtttattta
    10081 attataaatc agatacttat atggtagctt tttgtgaaaa aagatttaag tttatagact
    10141 ttaaattatg taggattaaa gattataagg ttttagaaga aaaatataat gtagataaaa
    10201 gttttagttg ggatgaatat agtaaaaata gtataggaat ttataaggga gaagaaatta
    10261 atgttgttat aaaaattagt catccatttt caacaattat aaaggagaaa gtttgggtta
    10321 ataatcaaca aatcatagaa tatgatgata aatctataat gtttaaagct aaaatgagag
    10381 gttatgagga gataaaaagt tggattttaa gtatgggagc ttatgttgag gttgtagaac
    10441 cagatagact tagaaatgat atattgtcag agattgaaaa aatgaaaaaa atttactgat
    10501 tttttcaaat aatttatact tggaccaata tacttcacgg tctagtgtta atatattaat
    10561 tgagagaggt gatattatga aaatgaaaat tgaatttagt acaggttgta taccaatatc
    10621 ttataattcg ctctttatga gtattataaa agaagcaata agaaaatcta atgaagatta
    10681 ctataaaaac atgtactatt ataaagaaaa gaataataaa aaaactaaaa attttacatt
    10741 ttcggtttat ataaaaaagt atagtattga aggtgacaat tttattatag aagataaagt
    10801 aatattaaat ataagtactc cagatttaga attgggtttt catatataca atgggttaat
    10861 gacttctaaa aaatgtttat ataaagacta tgaacttaca agaattagaa tcgatttatc
    10921 aagagaaaag aaggtaacag aagaaagggt actatttaat gcattgtctc caatctgtgt
    10981 aaagtctaaa gaaggaaaat tcttggagat aactgatgat agatacatag aagaactaaa
    11041 ctatataact aatgaagtgg ttaaaaatta tagggggaat ggattaaaaa gaaagttaga
    11101 atttgaaaat gtaggtttca aaaaggtagt agttaaagag agtttaagag aatttaaaaa
    11161 aataacaggt aaagagtatc aatatattaa tggttacaaa ggtaaattta tattgaaagg
    11221 tgatattgat gatttaaatc ttatctacaa tctaggaatt ggttttagac gtgctcaggg
    11281 atttggagat gtagatattt tagaatggag gtgagataaa tgaagttaag agtttataga
    11341 ggagattggt tttttaatat gggtatagtt ggatttttaa atataataaa gaaagcagat
    11401 aaacaagctg aaatatttat tatggaagat tatatcgaat ttgatagctt atttcttgaa
    11461 aactttcatg agtattattt taattacttt atggatgaat atgatgtatc aaaaagaatt
    11521 aaaaaaaata ttgattacag tataaatttt attaaatcta agcctgatag aatcaaagat
    11581 ggaattaaaa aaattaaaga tagtgtgaaa caacaaaatg ataagattaa aaaatttgat
    11641 gaagaaaaat ttaacctgat aaaagagaag ctagatagta tgtctaagat aaaaagttat
    11701 gatgaatttg acagtttaga agctttagta gatgagacta tagatatatt taaaataaaa
    11761 tcaataaatg acaggcttac agcaaatctt tataaatatg tagttcaaga taattatttt
    11821 ggacaagtta gtttttttaa tgttgctaag gcgaaattag atttagatgg attaaaacag
    11881 gtaatgttta atgattattt aagacaaatt atatattttg gagagttaga agatttatta
    11941 gaagagaatg actatgataa gttgaaaaac tatttaaatg atagattaaa tagtatagat
    12001 aaggatataa atgaaaaaaa agttagtaag tctagtataa atactataga aaaaattatg
    12061 aaggaaataa ataaaaactt tataaagaaa aataaaagca tagaagatat aaaagagtat
    12121 atggatagtt tagaagtatg tgaaatgtgt ggtttatata agggaatatt agatgaatac
    12181 tcagaaagta attttgctcc acttggagta agcaccaata atgctaggaa tatgttttgg
    12241 aatcaggcgt atgtaccatc aatatgtgat atttgtaagc taatattgtt ctgtactcca
    12301 gcaggggcta cttatacaag aaagaattat ttaattaatg aagaaaatga gttttattta
    12361 tttgttaaca tggatacttg tataaatgag ctttttgaaa gaaataatag tttaaaagtt
    12421 caaaaaagtg agtcttcaga ttccaaagat gaaaatcctt ttaatcagct tataaaaagt
    12481 atagtagaag aaaatacatt aaaaagtgaa tggcaacttc gtaatatact ttttgtggaa
    12541 tttaaagcaa gtatagattc taaaaaatgt aaaataaatt attttaatat tccaacttat
    12601 ttagcaaagt tttttacaga caagtatgca aataaaaaaa tacaaagtat ctatgattac
    12661 aagcttaaat caaatgtact agatttactc ttgaaaaata gggacttgaa gcatataacg
    12721 aataacattt taagaaataa agttaaaaat gatatggaaa gcaacaacaa atcaaatata
    12781 tcaggaatag attgttttag agtagtccaa ttaagagtat taataaatag ctacaaaaag
    12841 ggggtatata aaatggatag taaaaatttg gagaagaatg atgaaaagct gaaaataatt
    12901 tattatttag ggtgtgatat acatgactat tttgttaata aaaattctaa aaataaaata
    12961 gatggagtaa gctataaact tttaaattca gttaaagtcg gaaataaaag tgattttatg
    13021 gatacaatta taagagtttt tatgtcagct gaaaaacaga ttccagcatt tattttagat
    13081 atagaaattg aaaaagattt agactttgaa tctataggtc atgcttttat atctggatta
    13141 atttctggaa aatatgaagg aaaagataaa ctaccaaacg aaaaggagga aaaataagat
    13201 gaaaagaggg ttaacattta cagtaatagc acaagctcaa agtttaaact atggtgaagg
    13261 gataggtaat atatcagaat taaaaaaatt aagtagagat gatggaaata tgtatacatt
    13321 tgcatctcgc cagtgtttaa gatatgacat agtacgatta gcagcagaat tgtttaattg
    13381 gaatttacag gttgtcgata aagaaaaagg tactattcaa tttaaagata atataagtat
    13441 aagagaatca gaagaaatgg atttatttgg atatatgaaa acaaataaaa aagatgagaa
    13501 agataaaaaa ggaggttctt tgactagaga agctactgta agattaagta atgcgatttc
    13561 tcttgagcca tatagaagtg atatggattt tttaaataat aaaggatttg cagatagaat
    13621 aggagaacac cctaatcttg ctaacataga gcaacattta agttactata catatacagt
    13681 gactatagat ttatctaaaa taggcaagga tggagagata gaacttgata ataaagagaa
    13741 atgtagaaga gtagtagaat ttttagaaat aataaaagta ttgaatagaa atattagagg
    13801 tagacaagaa aatttatctc ctctatttgt agtaggagga gtatatgaaa tagcaaatcc
    13861 atttttcttg ggtagaatta aattaaaagg agataaaaat ggatttaaaa taaataagca
    13921 agctatagaa gaagtaattc aaggtacttt tttaggaaaa gatttaaaag aatttaccta
    13981 tgttggaatg gtagatgggg tatttataaa taaagaagaa tttaagggat tgtttgaaga
    14041 taatttttta agtgtagata aattttttgg acaactagtt aaagaagtaa aggaatatta
    14101 tggggtgaat taatatgaag gttttgaaat tagatttatt tcaagaaact gcatgctaca
    14161 aaaaaccatt tgctatgaag attacagaga catatccact gcctccatat tctacaataa
    14221 atggattaat tcacaaaata ttaaatgcta cagaatatat accatttaat ataagtgtac
    14281 agggaacata tgaaagtata tttaataatt accagacaac atatttttat aaaaaagata
    14341 gtattacatc tatgccaatg aatagtcata tgctattgaa tgtaaatttg ataattcata
    14401 taggtgggga ttttgattta ttggaagaaa tatatgatag tttattaaat tatgacgagc
    14461 atttatcatt aggtagaaaa gaagatttag taagaattaa tgatattaga tttgtagaag
    14521 tcaataaatt tgaagtagat gaggatatac aattagatga ttatgaaaat tataagttat
    14581 cagaatgtaa tataagaatg cctatatata taccaaaaac aagtttacaa gatacagata
    14641 tagatggtat aagttacaga ctcaataatt actatgataa taatgctgtg gaagataaaa
    14701 aaagggtttg gaataaggta gatagttatt atgttgagga tggaaatact atatcaattg
    14761 gagatatatt attagataat gaaggagatt tattatattt taataatata aattaggagg
    14821 gagattatgt tatatgctaa atctaatcca gtggaaacac ttagagaaca tactgatgaa
    14881 cttttaaaac aaatgaatgt attaagagaa agttatggaa aaaatataaa tagcttagat
    14941 tttctagaag aggagatatt ttggcaatta cttgactttg ttatagaatt tcatgatatt
    15001 ggaaaagcat tttcaccgtt tcaagagtta ataaaaagca gaatggatac taaaataaat
    15061 gaacctaaaa tagtaactca tttagaaaat aatgtaggcc ataattatct ttctcctgca
    15121 tttattgatt atagttatat agacaggaaa aaaaataaag aacttagagc agtattaaat
    15181 caagttattg tatatcatca tgaaagagat atctttatag ataaagattt taaaaattta
    15241 atacaaaaaa tattagatga agatttaata aataaagttt atgaactaca gcatgaattt
    15301 aaagttagat atccaataaa aacagaaaaa ttgagtaaag tatatctaca aagtgtagaa
    15361 aaaagaatag ataaaaatca caagtactat aatttatata ttatgttaaa aggaatacta
    15421 catagattag accacagtgc ttctgcccat gagattgtag agtgcaatag taatatgaat
    15481 ataggcgaat acacagaaaa acatttagta aaagagtttg gtagtttaag agaagttcag
    15541 tcatttgcta aatcgaatag aaacaagaat ataatactaa ttgcatctac agggatggga
    15601 aaaacagaaa ctgctttgat ttggatagat aaggataaag cattttttac actaccatta
    15661 agagtaagta taaatgcgtt atttgatagg gctaaaaata taattggagt aggagaagca
    15721 aatgatacat tcttaggtct gttacattca acagcaatag attatttaga agaaagtaat
    15781 caggaaaatt caaatgagat tgtagattta gcaaagttat tatcttgtaa actgacattt
    15841 tccacaatag accaaatatt taaatttcct tttttgtata gaggctatga aaaagtgtac
    15901 tcaacattag catattcaaa agtagtaata gatgagatac aagcatattc accagaaata
    15961 gcagctgtat tggtaaaagg tatagaaatg atacataaga taggtggcag atttatgata
    16021 atgacagcta ctatgccaac catatatata gatgaattaa aaaaaagagg tgtaatgaat
    16081 agtaacttag ctgacttgac atgtaacaca gaaaaaataa gacattgtgt gtctattgta
    16141 gaaaattcaa tagatgaaaa cttaggtaaa ataatacaaa atggaatgaa taaaaaagtt
    16201 cttgtaatag taaatacagt taaaagtgct gtagaaaaat atgagttaat agaagaaata
    16261 gttaagccaa aaggaataga tgtcaactta aatcttttac attctatgta tatacaagaa
    16321 gatagagcaa aattagaaaa atatataaaa gaatttgcag atagtgatag taatggtatt
    16381 tggattacta cacaattagt ggaagcatct cttgatattg attttgatga gcttcataca
    16441 gaaaattcaa cacttgacag tctatttcaa cgatttggta gatgttatag aagtcgtgag
    16501 tatgaagaaa atagcccaaa tatatttata tatacagaaa aagctacagg aataggtagt
    16561 atttatgata aggatattgt agaaaaagga cttgagctac tgaaaacttt tataaatgga
    16621 aaagaatgtg tgaagatgaa agaaaaatat aaggtagaaa tggttaagat actatactct
    16681 aaagaaagtc tagaaggtac agcttttgaa aagagattta ccagtgcttt aaatatttta
    16741 gatactataa cgccatatag tttaggttct aaagatgcac aaaatatact tagaaatatt
    16801 gaaggatata cagtaattcc agaggatata tataataaaa ttgaagaaac tttaatcaaa
    16861 gattatgaag agttgggaca agagcttata aatgcatata gtaatgatga tagacaattg
    16921 ataaataaaa taaagtctaa gagaaaaaaa gcaagaagag agataattaa aaaaactgta
    16981 aatttaccaa tatataaagc taaacaaaat gtaattgaca tacaggtgaa aggtcttgaa
    17041 gatttaaaaa tacttttata taaatatgat atatacgaaa ataagcatac aaaacagata
    17101 tttggtaaag gtgtgcttat aagtaatgaa atagaccaat ttatttgatt tttatattaa
    17161 caatgtggct aaaatttact aaagaaggtg attttgtgcc aatagattta gaagtattaa
    17221 aagttcaagg tgtaaaaata aattattatt atgtatgtaa aagaaaatta tggctatttt
    17281 ctaaaggaat aaccatggaa caaaatagta gtagagtatt gtctgggaag atagtacatg
    17341 aagattcata taaaagaatg aaaaataaag aaatattgat tgatgatatc ttgaagctag
    17401 atataataaa ggacgagtat gtaaaagaag taaaaataag ttcaaagatg aaagaagcag
    17461 atgaaatgca gttatactat tacttatact atttaaagaa tagtatgggt atagagaaaa
    17521 aaggaactat aaattatgtt aaggaaaaga aacaagaaga attgatattg acagaagaaa
    17581 aagaaagaat tattgaaaac acacttataa atataaatga aataaatatg cagttatctc
    17641 ctcccaaaat tgagaaaaaa cattattgta caaaatgtgc ttattatgaa ttttgttttg
    17701 tgaaggagga gtaacaatgt ataaagacta ttatattata agtaatgggg atataaaaag
    17761 gaaagaaaat acgatttact attacaattt agaaggtgag aaaaaaatat taccagtaga
    17821 acaagttgat gatattcata tatatggaga agtagattta aacacaaaac ttataaatta
    17881 cataagtaaa tatggggtga tgcttcattt ctacaattac tatggatatt attcaggtac
    17941 atattatcca aggaagaaaa atgtatcagg attcagttta gtatgtcaat cagcctgcta
    18001 tttagataaa aatgaaagat tatacttagc aaaatccttt gtggaaagtg catcatacca
    18061 tattttaaga aatatgagat attacaaagt tgatgaaagt ttaattgata ctataaagga
    18121 tgaactaaat gatttgaatg atgtcaaaga aatatcagaa cttatgggta aagaaggcag
    18181 aataagaaaa acatactata aatcatttaa tcaaatatta aaagatgatt ttgaatttta
    18241 taaaagagaa aaaagacctc ccaaagaccc agtaaatgct cttatgtctt ttggaaatag
    18301 cataatgtat acgaatgttt taagtgagat atataagaca caacttgacc ctacaataag
    18361 ctttttacat gaaccatcaa caaagagatt ttctttaagt ttagatattg cagaaatttt
    18421 taagccaatt ataattgaca caataatttt tagcctgatt aataataaaa gaattaataa
    18481 gaatgatttt gaatatcaag acaaaatttg ttatttaagt gaaaaaggaa agaagaaatt
    18541 tttgcaagaa tttgaaaata agatgcagac aactataaaa catagaaatc taaatagaaa
    18601 agtttcatat agaatgttta taaggttaga gtgttataaa ttaattaaac attttataaa
    18661 tgatgaaagg tacaaagttt taaaggtgtg gtggtaagta tgtttgttat tgttacttat
    18721 gatattgttg aagcaaggtc gttaaataga attagaagga tacttagaaa atatttgact
    18781 tggacgcaaa attctgtttt tgaaggcaat attactgaag gaaagttaca taaatgtatt
    18841 tctgaaatag aaaatattat tgataatagc gaggattcaa tctatgttta tgagataaaa
    18901 aatcctaatt caattaaaaa gaaatgttat gggattgata agtattctga tgaaatgttt
    18961 atataggttt gcagtgagcg atatttatgc taaaataggt gttaacagtt ggaatataag
    19021 ggattgaagg tgtatgataa ctgttatcaa ttgcactgct gctcgctcac tgcaaatttt
    19081 gatgttttta ttgaattata attgcttgat tgaagtgttt tcaatgtatt caaatatacc
    19141 tattttgggg ttttatatta actaagtggt atgtaaatga agctatgtcc cttatagaag
    19201 gtgcataacc atacagtttt atattaacta agtggtatgt aaatttctaa aagtaacaaa
    19261 ttattcgaag tagaggcagg ttttatatta actaagtggt atgtaaatat actcatcatc
    19321 agtaagaaga ttacaagata aagcacgttt tatattaact aagtggtatg taaataatat
    19381 aattataaca caggagttcc ttaaatgaaa agttttatat taactaagtg gtatgtaaat
    19441 cttgatttca atgaaaaaat aaagaactat tcagaaagtt ttatattaac taagtggtat
    19501 gtaaatctaa aattatgttg attttttagt ggagttgtgt tatgttttat attaactaag
    19561 tggtatgtaa attttgtata taaaactgat attttaaaga ctactgattg ttttatatta
    19621 actaagtggt atgtaaatac aaaaacatct tctccaggaa ctccaatcaa atcgcgtttt
    19681 atattaacta agtggtatgt aaatttattc aattcctcca cataaaaatt ttatttttaa
    19741 tgttttatat taactaagtg gtatgtaaat agaacaagag cccaaacaaa agccggttta
    19801 aaaaaatgtt ttatattaac taagtggtat gtaaataagg tttgacctgc gtttttatat
    19861 gcatctgaat aacgttttat attaactaag tggtatgtaa atcgagttgg catccaagca
    19921 tttttcacag attttaatag ttttatatta actaagtggt atgtaaatac aatagacagt
    19981 atattgagta tctccactaa gtgttgtttt atattaacta agtggtatgt aaattgaaac
    20041 aaaatgctga tgcaagaaaa gaaagtatcc gtgttttata ttaactaagt ggtatgtaaa
    20101 tcgaatttca tggctttgaa tttatttata tgtagttgtt ttatattaac taagtggtat
    20161 gtaaatccaa ttaagttact agataaaaaa atagaacaaa ttagttttat attaactaag
    20221 tggtatgtaa atacaaaaaa acgtataata aaaataattt ctatctctgg ttttatatta
    20281 actaagtggt atgtaaatca tattcttcat ttatccctat tctatctaat atttgtttta
    20341 tattaactaa gtggtatgta aattttaaaa ggtcaactta aaggtagtaa ttttttaata
    20401 gttttatatt aactaagtgg tatgtaaata ggataaagaa aagactcaca caagacacag
    20461 tgtcaggttt tatatcaact aagtggtaga taagtagaat attagcaata tcaacgagta
    20521 tttagaaact tattttatat taataaagca gtatataaaa ttgtagaatc aacaatagca
    20581 tatactaaaa catccacctt atattaacta aatcatatct aaataaaata cacttaccta
    20641 caaacattat aaaatcaata caaaaatgag gtgaaacaaa atttatgata aagaaattaa
    20701 acagtaaaga cataaataaa atcatggaaa tatgggaaaa aagtacaatc aaagcacatg
    20761 actttataag taaagaatac tggcaaaata actataatac tgttaaaaac gaatatatac
    20821 ctatatcaga tacatttgta tatgatgatg gagatgaaat aaaaggattt ataagcataa
    20881 tagataaaag ctttatagga gctttattta taaagcccaa ataccaaaat ctaggtatcg
    20941 gaggtaaact tttagattat gcaactaaaa aatataaaag tctaaactta gcagtatata
    21001 aagataataa aaaagcagtt gtgttttata ataaaaaagg ttttaatata gtaaaagaac
    21061 aagtaaatga agattcagga tttaaagagt acataatgga atatagtaaa taatatgatt
    21121 acattctatt aaaaggataa ttaatttatt tgccatttga ttttttaaga gtaattttta
    21181 aaatagacta tatgaagata aagatattta ttatagatgt aagttaatca gaattgatat
    21241 agctacaaaa gaggaaaata aaattgtatg gtgtatttca gatttaacaa atttactatt
    21301 taaagataat aagtttgata taatattaaa gatactttca cctataaact atagggtatt
    21361 tgaaagaatt ttaaataatt atggaatgct aataaaggtt tgttaaaatt taataattat
    21421 tagattatag aaaattgcca tgaaattagt tcatcaagaa ctagtttcat agcaatttta
    21481 attcgtataa gtgtatttat ttttacagat ttaaaaaact tatacagtat ctaataatgt
    21541 aatcttattg ctttagccta taaatattta aatcttaaaa tgttctcttt gagataagct
    21601 tatttcagag tcacaatttc cacaacagta agatgttgag acatctttaa atttttcagt
    21661 attctcatca aagttcattt ttttctttgc aataattcct accttagtta aattagaacc
    21721 acaattatta cagttttgaa ttttgcataa gttatatagt ttatcaagtg taatatcttc
    21781 taataattca tcacaattac aacatctgat agaagaaact tcactacaca tttcaatagg
    21841 ttcagcttct ttagaagaaa atttatatgt tatgtcattt gatactttat aacctgtatc
    21901 aaatatatta gaattacaac ttggacataa gtactttgga agatatatat cttttttttc
    21961 aaaagtatca ctactaatat tacagtttaa ttcatctaaa attggtcttt catctaggtt
    22021 attaccttta tttaagctta gaagataatt ataaattttt ttatcttcac tctgttttga
    22081 tgtatctaac aaatgctcca ttatattagt gtattttttg ttttttgaag gcatgtttaa
    22141 attcagataa ttgttttcaa tagcaaagca tactatattg aaatagttat atttaactgc
    22201 aaaaaataat aacatttcat caaatacttt atctattatt ttgtcagaaa tacttatcca
    22261 aaaatctggg gactctaagt aaactttcct actaagttca tctaactctt catctatatt
    22321 attttcatta actttcatat catcacttcc ttttaaatat cttgtgtata aactatttgt
    22381 tactattttt tatataaaat aaaatcttat ataaaaatat atcatattat aatttacaag
    22441 tatagtctaa atagagctgt ttttaagcaa agttttataa atgactatta aaatataaag
    22501 taacagtata aagtttactt ataaattaaa tgtaaaccta aatgattata atagttgaca
    22561 aaaaaatgtc tttattttat actaaaacaa agctttaata gaagctttgt atatgtacat
    22621 ataaactaaa tgaaataaga catatgaagg gaattataaa aatgaaaaat actaaagtaa
    22681 atattcaaga tttaactaaa atgtcaatat gtgtagcatt attgtgtata tcatcttaca
    22741 tatatatacc attgccattt actccagcag gagtaacagc acaaacaata atgataaatt
    22801 taatagcttt gattttaaca ccaagacaag catttagtac agttggtgta tatataatga
    22861 taggtttaat tgggattcca gtatttggtg gaggtacatc tggtattgga aagttgttaa
    22921 gcccaacagg tggtttttat tttgggtttt tgtttgcagc actaattatt agtttattaa
    22981 aaggacgaaa caatgatatt aagagatata tactaataac aatttttgtt ggaatgccta
    23041 ttatatattt tatgggaaca gtatttatgt gctattttaa tcaaatgaca gtagaagcag
    23101 cactttttgc agcagtagta ccatttttaa ttggagatac aataaagtcg gttattgcat
    23161 cttttttagg cactaaactg aacaatgtac tcagaagaaa tctatgataa atctataata
    23221 taaggaaggg tgtaatgtat ggaggaagtt tttatattag gaggattgag aagtcatata
    23281 ggtctaaaaa atggaatttt tcaatttgtt caacctgaat tactaggagc aagtgtttta
    23341 aaagatttaa ttaaaaagta tgaaattgat aaaattgatg agattatatg tggaaatgca
    23401 gttgggacag gagggaatat agctagatta atgactttaa cagcaggagt gtcaaatgaa
    23461 gtacctgctt ttactgtgga tatgcagtgt gcttctgcta tgatgagtat agacatagct
    23521 ttttcaaagg ttaaatctgg tcagtgtgat ttaattattg caggtggttt tgaaagtagt
    23581 tctctacaac caatgcgcac atatcataag aatgataagc gatataatac aaataatcca
    23641 aattatacag ttgctcaatt ttctcctgat gataatagcc aaaatagtat gctcgaaggt
    23701 gcggaaagag tagcagagtt atatcaaatt gagaaagcag acttggattt ttgggtaaag
    23761 gaaagtcata aaagagcaaa agaagcaaga gaggaaaaaa tacttgaaga tattatatct
    23821 cctataaata atagtaccta tgatgaaggt atacgtgata agatgagtca aaggttatta
    23881 gataggatgc catcaatttt aggaaaagaa actattacaa atgcagcaaa ttcatgtctt
    23941 attaatgatg gagcttcatt tattataata tgttctaaga agtatttaga acatgtaaaa
    24001 aagaagccta aagcaaaaat tattaataca tgcacaatag gaacagatgc aaccttaagt
    24061 ccaacatcag cgatacaagc aatggataaa cttttagaga tagaaagtct taattattta
    24121 gatgtatctg ctgttgaatt taatgaagca tttgcagtta tagatgtgtt gtttcaaaga
    24181 aaatatccag agttaataga tagatataat atatttggtg gagctttagc gtatggacat
    24241 ccatatggtg cttcaggtgc aattattgca ttacatcttt taaaagcatt agaaaagact
    24301 aagggtagat atggaatttg ctctatagct gcagctggtg gtctaggttc agctttactg
    24361 cttgaaaggg tgtagattat gaactattat gaacttttaa gaataaaaaa agagaggcat
    24421 aaaaataaaa attttttaat tatagatgga gaaaaatata cttatgaaaa tatattgagt
    24481 tatagtgagg aactaggaaa acaaatttct ttaggtgaaa atatcccaat tttaatatat
    24541 tctaaaaata taatgtttca gttgattagt ttttttgcta ttaattattc aaaaaatatt
    24601 cctattattt gtcattataa tctttctaaa aaagtattag atgatatttt attaaaaaat
    24661 aatatttcaa tcattatatc tgatgaatct atggacgtta ttgatttata tgatgataac
    24721 aataatgaag tagcaaaaaa agttaatttt tctattttta atcctaaatt taatatatat
    24781 atgtatcaat ataagaacct tataaattat ttagataaaa gtatttgtat gggagcttta
    24841 tcttcaggtt ctacaagtgt tccaaaggta ttatatagaa catatgagag ttgggctgga
    24901 ttttttccta tacaaaatgg tatttttaat atctctgggg aatcaatctt gtttgttaat
    24961 ggaacactta gttttacagg gaatctaaat tctataatgt cagtattata tgaaggaggt
    25021 agtattgtaa taagttcagg tcttaattgt aaatcatgga taaggataat aaaacaatat
    25081 aatgtaacta acatatacct tatacctaca aaacttcaac ttttggttaa acacttaaaa
    25141 gaaccagtac tcaaagttgt aagtattttt acagggtctc aattattatt tgaagatact
    25201 gcaagaaatc taaaaaaata tatgccaaag tctgaaatta ttttatacta tggggcaagt
    25261 gaattaaatt atattacata tttatgctat gatgaactaa ttgaaaaacc tctaagtgta
    25321 ggcagaccat ttccaggaat agatatatat attagagaag gaaaaatttt tgtgaataca
    25381 gaatatgcag tatataatgc aaccaaacct tattctgtca atgatattgg atattatgat
    25441 aatgatggat acttaatatt tgaaggaaga agtgatgaca ttttaaatat tggaggattt
    25501 aaagttagtt ctactaagat tgaaaatgaa gttaaaaaaa ttcctcaaat tgaagatgca
    25561 attgtattgc cgtactcaga cactataaga ggaaatcaaa ttgtattatt tgtaataact
    25621 atagacaaaa ttacgaagaa agatttgttg attaaaatga aagataatct aatgaaaaat
    25681 gaaattccaa agaaaattat ctttttaaat tcatttccat atacctcttc tgaaaagata
    25741 gatagattag cattattaaa aatgttataa gtataatatt tagtaatttt agtgaaccaa
    25801 tgtattgata aaaacatatt gtatatagta aaggaggctt acaatatgtc aaatcaatac
    25861 gatataactg ttattggggg agacctgcga caagtgtaca tggtaaaaaa actaattaat
    25921 aaagggtatt ctgtagtcac ttatgggata tcaaatgaaa ttataaatgg aatcgttgga
    25981 aaatcaactt cactagctga agcactatcc aaaagttcca ttattttatg tccaattcca
    26041 tttacaaaga atcaagttaa tattgaaaat acggatgatt gtcttgatgc tactattgat
    26101 aacttgctaa ttaatttatc tcctaatcaa atattatttg gaggtaacat accaactaaa
    26161 gtttgtaaat tttgcgagca acactctatt cagatttatg attttatgaa aatgaatgat
    26221 gttgctattt taaatgcagt tgctacagct gaaggggcta tagcagaagc tattaaaaga
    26281 agtataatca atatacatca aagtaactgt ttagtattag gttatggaag atgtgcacaa
    26341 atacttgcaa aaaaattata cactttggat gcaaatgtat gtgttggcgc aagaaataat
    26401 gatgcaagaa gtacggctaa tgcatttgga tattccagta tttctttaag tcaacttgat
    26461 gaaaaacttt tacaatttga ttatattttt aacaccatac cagagtgtat tttaacgaaa
    26521 gaaaggttag aaaaagtatc acaagaagta actattatag atatagcttc ttctcctgga
    26581 ggagtagatt attctgttgt taaagaagca gggattaatg cgactctttg ccttgggctt
    26641 cctggtaaat attcaccaaa gacatctggt gaaattcttg ttaacgctat agaaaatatt
    26701 ataaatgaaa gaagggatta gaaatgagac ttgaaggact tacaattgga gtaggattta
    26761 ctggttcgtt ttgtacttat gataaaatat ttatagagtt agagaatttg gttaaagaag
    26821 gagctaatgt acacactata ttttcagatg tatcacaaaa tatcgattgt agatttggaa
    26881 attctgaaga gtttatgaaa aaagcatatg aacttacagg aaataaacct atagttacga
    26941 ttgaagaggc agagccattt ggacctaaag gaattgctga tattataata atagctcctt
    27001 gtactggaaa tactgctgca aaattagcaa atggtattac agattcacca gtattaatgg
    27061 cagcaaaagg tcatcttcgt aatgataaac cactagtaat atcaatatca acgaatgatg
    27121 ctctaagctt taatttcaaa aatattggca ttctccttaa ttctaaaaat atatattttg
    27181 taccttttgg tcaagataat tgcaaagcaa agcctaattc tatgattgca catactgagc
    27241 taataattcc aactatagaa cttgctctag agaacaaaca gctacagcct gttataaaaa
    27301 gtccacatca atagaattgg ttcttataat attatgtatt agatacaata ctagcaaaga
    27361 ggctgtctca aaatagagag aagcctcttt ttcttgttga aatgatgaaa atatatttaa
    27421 tttcatacaa aaaaatgcct catggactaa aaagtctatt ttgagctaat ctccgtaatt
    27481 tttggtatat taaaattatt tacttaatcc aatttttaaa ttagaattta tatcgttttg
    27541 actcttcaaa tatcaatcta actgttgttg atacaaaaga agaggacata attaaaacaa
    27601 ataccgatag tcctctaata aacaaattat ctacataata agttactatt ccaatacctc
    27661 caatcgttaa aattacactt ataatcaaag aaaaaatgct aattgttttt aattttttca
    27721 tgcttatcct ccttcttata aacttcaaat t
//
LOCUS       DAEPXW010000050        27167 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.051, whole genome shotgun sequence.
ACCESSION   DAEPXW010000050 DAEPXW010000000
VERSION     DAEPXW010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27167
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.051"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            74..958
                     /locus_tag="KRM55_002145"
     CDS             74..958
                     /locus_tag="KRM55_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH1594385.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            1057..2232
                     /locus_tag="KRM55_002146"
     CDS             1057..2232
                     /locus_tag="KRM55_002146"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBH1594386.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            2360..3214
                     /locus_tag="KRM55_002147"
     CDS             2360..3214
                     /locus_tag="KRM55_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594387.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            3258..4493
                     /locus_tag="KRM55_002148"
     CDS             3258..4493
                     /locus_tag="KRM55_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBH1594388.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            4594..5535
                     /locus_tag="KRM55_002149"
     CDS             4594..5535
                     /locus_tag="KRM55_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBH1594389.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(5754..6107)
                     /locus_tag="KRM55_002150"
     CDS             complement(5754..6107)
                     /locus_tag="KRM55_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH1594390.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTKKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            6403..7314
                     /locus_tag="KRM55_002151"
     CDS             6403..7314
                     /locus_tag="KRM55_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBH1594391.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            7574..8008
                     /locus_tag="KRM55_002152"
     CDS             7574..8008
                     /locus_tag="KRM55_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594392.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEMLGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            8031..9566
                     /locus_tag="KRM55_002153"
     CDS             8031..9566
                     /locus_tag="KRM55_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594393.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDVILVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     GSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEEVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            9650..11017
                     /locus_tag="KRM55_002154"
     CDS             9650..11017
                     /locus_tag="KRM55_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1594394.1"
                     /translation="MKECIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            11052..11276
                     /locus_tag="KRM55_002155"
     CDS             11052..11276
                     /locus_tag="KRM55_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBH1594395.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(11724..12122)
                     /locus_tag="KRM55_002156"
     CDS             complement(11724..12122)
                     /locus_tag="KRM55_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBH1594396.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(12125..12526)
                     /locus_tag="KRM55_002157"
     CDS             complement(12125..12526)
                     /locus_tag="KRM55_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1594397.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            12885..13871
                     /locus_tag="KRM55_002158"
     CDS             12885..13871
                     /locus_tag="KRM55_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1594398.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            13855..14766
                     /locus_tag="KRM55_002159"
     CDS             13855..14766
                     /locus_tag="KRM55_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1594399.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            14879..16447
                     /locus_tag="KRM55_002160"
     CDS             14879..16447
                     /locus_tag="KRM55_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1594400.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            16522..17547
                     /locus_tag="KRM55_002161"
     CDS             16522..17547
                     /locus_tag="KRM55_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594401.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            17540..18484
                     /locus_tag="KRM55_002162"
     CDS             17540..18484
                     /locus_tag="KRM55_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594402.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            18843..21500
                     /locus_tag="KRM55_002163"
     CDS             18843..21500
                     /locus_tag="KRM55_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1594403.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLKDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            21715..22344
                     /locus_tag="KRM55_002164"
     CDS             21715..22344
                     /locus_tag="KRM55_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594404.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            22479..22805
                     /locus_tag="KRM55_002165"
     CDS             22479..22805
                     /locus_tag="KRM55_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1594405.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            22821..24110
                     /locus_tag="KRM55_002166"
     CDS             22821..24110
                     /locus_tag="KRM55_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1594406.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            24134..24463
                     /locus_tag="KRM55_002167"
     CDS             24134..24463
                     /locus_tag="KRM55_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1594407.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            24611..25939
                     /locus_tag="KRM55_002168"
     CDS             24611..25939
                     /locus_tag="KRM55_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1594408.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            26256..27116
                     /locus_tag="KRM55_002169"
     CDS             26256..27116
                     /locus_tag="KRM55_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBH1594409.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEIEEGIAIWRGNITNLRANAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
BASE COUNT        10861 a         2799 c         4856 g         8651 t
ORIGIN      
        1 ttatgaatta caatttatat aaactaataa aaattaaata atattaatca acttattgaa
       61 tggaggaata aaaatgaaat ttgtgacttt ttgtagtagc aatgaagaaa aaataggtgt
      121 atttaattca gaaacaaata gtatatatga aattaatagt ttaggattaa gtaaattata
      181 tactgatatg aatgatttta ttgaaaacgt atctacagga gatttagaaa aaataaaaaa
      241 caattcattt gaaaacgcaa agtgttataa gttagaagaa gttaaattat gttccccaat
      301 tgtaagacct aaaaaagata ttatatgttt aggtctaaac tataaagacc atgtcaatga
      361 aatcccagat ggagttataa aaaacgtagt tatgccagat tatccaattt atttttctaa
      421 gagagcagac aaaataattg gagtggatga taagataagc ttacatggag atttggtaga
      481 gaagttggac tatgaatcag aacttgcagt aatcataggt aaagaaggta taaatatatc
      541 aaaagaagat gcttatgaat atatatttgg atatacaata gtaaatgata taagtgaaag
      601 agcacttcaa gataaacatg ttcaatggtt tagaggaaaa agcttagaca cacatacatc
      661 tatgggacct tgtatagtac ataaagaaga atttgaacat cctttaaaat tagatataag
      721 tagtgtagta aatggagaag taagacaaaa ttctaataca gagtacttta tatttgatat
      781 acctactata ataaatgatt tatcaagagg aatgactcta aagccaggag atataatttc
      841 aactggaact ccagcagggg ttgctatggg gatgaatcct caagtatatt taaagcatgg
      901 cgatatagtt gaatgtaaag tcgaaggaat aggagtttta aaaaatatag ttgattaatg
      961 gataaatatg ccatataatt ttattagtac gaataattta attaatatag gattaatcaa
     1021 acttatgatt aatttattat agagagggat gagtatatgg caagagaact agaattaaag
     1081 tatggctgta atccaaatca aaaaccatca aagatttata tgaagaatgg agaacttcct
     1141 atagaagtat taaatggaaa acctggatac ataaattttc tagatgcatt taatagttgg
     1201 caacttgtga aggaattaaa agaagctaca ggtcttccag cagcaacttc atttaaacat
     1261 gtaagtccag caggagcagc agtaggggta cctttatcag atactttaaa gcaaatatat
     1321 tttgttgatg atttagagct ttctccatta gcttgtgctt atgcaatggc aagaggagca
     1381 gatagaatgt cttcttatgg cgattttata gcactttcag atgtatgtga taaggagact
     1441 gcaactatta tagcaagaga ggtttctgat ggtataatag ctccaggata tacagatgaa
     1501 gcccttgaaa tattaaaagg aaagcgtaaa ggcaactata atattgtaaa aatagatgaa
     1561 aactatactc ctgaacctat tgaaacaaag gatgtttatg gaattacttt tgaacaaggt
     1621 agaaatgaaa tattaataaa tgaagaccta ttaaaagata ttccaactga taataaaatt
     1681 tttacagata gtgcaaaacg tgatttaatt atagctctta ttacattaaa atatacacaa
     1741 tcaaattctg tttgttatgc taaagatgga caagtaatag gggtaggtgc aggtcaacaa
     1801 tcacgtattc attgtactag acttgcaggt aacaaagctg atacttggta tcttcgtcaa
     1861 catcctaaag tattaaactt aaaatttaaa aaggatatag gtcgtccaga tagagataac
     1921 actattgatg tatatctttc tgatgattat atggatgtgc ttgctgatgg catatggcaa
     1981 aacttttttg aagaaaaacc agagcctcta actggagaag gaaaaagagc atggcttaaa
     2041 actttaacag gagtagcact tggttcagat gcatttttcc catttggaga taatatagaa
     2101 cgtgcaaaaa gaagtggagt aagttttata gcacaaccag gtggttctat tcgtgatgat
     2161 aatgttatat taacttgtaa taagtataac atagtcatgg catttactaa gaatagatta
     2221 ttccatcatt aaaatactga aagtataaag ataatataga ttaagtaaaa atctacaaca
     2281 agttttgttg tagatttttt tatttgctgt ataattttaa atagaacttt atttttagat
     2341 attcaatttg gaggttgata tggctttaaa tataagaaac tatagcctat tatgtaatca
     2401 aggaacagct aaatttaatg aagatgtagt cggtataaat ccatttgggg catgggtttt
     2461 agatggtgct acaggactta atggaaaaaa tttagtgtca actgaaagtg acgcaaggtg
     2521 gtatgttcag tggtggaata ggtatttata taaaaatata aataaagaag aatcattaaa
     2581 gagtattatt aatactggaa taatagaagt aaaaaaagag tatgaactaa gattaaatgg
     2641 gtttaaggtt gaaaaattag atttaccatc tagttctata gttgttgtaa aatttcatga
     2701 aaataaagta gagtattttt tattaggaga ttgtgctttg tttattaaaa atggagattc
     2761 caaagttata aaagatagga gtatttgtaa atttgataat actgtatttg atgaaatgag
     2821 taaactttct aacttggaag agatggcatt tgatgagatt agaactagtg ttatggatac
     2881 aatagtaagc aatagattga agaaaaatac aaaagagggc tattggatat tggattttga
     2941 tgaggaagct gtggaaaatt ctatatatgg atacattgaa ataaaaaaag attttcaatt
     3001 gatgctaacg agtgatggtt ttacaagtgc atgtgataga tataatctaa taaaagaaga
     3061 agaattgata cgtatagcag aaaaatttgg tataggatat atacacaata aagtaaggga
     3121 ttttgaagat aatgactata aagcggttaa agtgccaaga tttaaagtaa aagatgattc
     3181 atcttgttta tatttagata tatataatga ttagactgta taaaactatt taattttaga
     3241 aaggaggcaa gtgaaaagtg aaaattcttc atataataac acaaaaacca aatagtacag
     3301 gtagtggtat atatttgtct ggtatgataa aagggttcga aaaaatcggt cataagcaag
     3361 ctgtaattgc aggtatagat gtaaatgatg atgtaaattg ttttccaagt gaagtaagtt
     3421 tttatccagt aaagtataat tgtggggagt taaattttcc tgttgtaggt atgagtgatt
     3481 ctatgccata tgaaagtaca agatataaag atttaaatat agacatgata aatagattga
     3541 aatatcaatt taaagtaaat atagataagg ctatgaatga ttttaaacca gaacttataa
     3601 tatgtcatca tttgtacctt ttaactgcat ttgttaggga aatggtaaaa gatataaaag
     3661 ttatgtctat ttgtcatgga acttgtttaa gacagttaaa taccattgat ttagagaaag
     3721 aatacataat agcaaatata aggaaattag atttaatatt tgctcttcat gaaaatcaga
     3781 aatatgatat tataaagact tttggagtaa gtgaaagtaa agtagttgta attggtagtg
     3841 gttataatga tgatatattt tataataaaa attataaaat aaaggatgat aaaataaaaa
     3901 tagtatttgc aggtaagata tgtaaatcaa agggactgat tccatttata aaagctatat
     3961 ctaaattaaa atatagtaaa gatttaatag aagtcaattt tgcaggtact ggaagcgata
     4021 tcgaatcata taatgagata gttaaactgg caagtaagtc tccatttaaa atgaatttcc
     4081 taggaaagtt agaacagaga gatttagctg agctattcaa caggtcacaa atatttgtgt
     4141 taccatcatt ttatgaggga ttaccagttg tagttttaga agctttatct tgtggcacag
     4201 atgtaatcac tactgatatt cttggtgtta aagagtggat tggtagtgag attaataatt
     4261 ctggaaagat agaatatgtt tctctacctt ttatggagaa agaaggtatt ccaaaagatg
     4321 aagagttata tgattttgaa aataatttgt ataatgcaat agattctaag atacaatctt
     4381 tattgaataa ctcaaataag aaaacatctg tagatatgtc aaaaaaaacg tgggatggct
     4441 tagcatatag aataaatgaa gttattttaa tggatgaatt gtgtttagtc taaaattatt
     4501 taaattataa aaaagtgtaa ctatttttac actattttta aatgatttta tattatacta
     4561 atactaaata tatttgtttt agggaggtaa tttatgagga ttagtaaaaa ggtattggcg
     4621 ttaggtattt cagcattact gttaagtgtt agttttccaa catcaataaa cgcactagat
     4681 aagattgaaa atattcaagg agtagataaa tatgaaacag ctgggcttat ttcagataag
     4741 caagatttta caacagcagt tcttatcaat gcagattcta caatggtaga tgggattgct
     4801 gcaagtggtc ttgcaggagt aaataatgca gctattttat taactaataa ggatgatata
     4861 ccagaagcaa cacttcaaag actgaataga gttactaaga tatatgtaat aggtggagaa
     4921 aattctataa gtaaagatgt agaaaaaatg ttacttatga gaagaatgca agttataaga
     4981 attgatggtg tagatagagt agatacaagt tataaaattg caggcgaaat agaaaaaatt
     5041 aaaaacagtg ataagatgtt tttagtaaat ggatttaagg atgaagctga tgcagtaagt
     5101 gttgcatctg ttgcttatag agatggagct cctataatat tgacaaaaga tataccttca
     5161 gcagaagaag acacagactt agacccatgg tttggagttt ctcctgttcc agtatatgct
     5221 attggaggag agtctacatt aagtgattac atagtgagca gatatagagc aactagaatt
     5281 ggcggtgttg atagatatca aactaataaa aatgttattg aaaagttcta taatggagca
     5341 aaagagttct atataacaag tggagatgat ttagtttatg ctttagttgc atcaccactt
     5401 gcaaaaaatg ctcctgttgt tttagtttca aataaaagtg ataagagtat attaagtgga
     5461 gctagtaaag taacagcaat aggtataagt gataagagta ttatagagca atgtttggat
     5521 gctgtaaaga agtaatggag tgttattagt aaaatgaata tacacattga aaattagtag
     5581 attgttcatt ttataatggt ataaaatata tgggaagagg ctatcaaatg gagataagcc
     5641 tctttttcat tgttaaaatt atgaaaagat actttatttt atataaaaaa gtatcttatg
     5701 aactaaatgt ctattttgat atactatctc cttttcttat attatattat tttttatatg
     5761 gaataaattt cataagtatt atcttccttt aatttttcta accaaaccat ctctaaaata
     5821 tctagttctt ctaaatagtc tttctttgtt ttgttatcat catgttttat aagttctaaa
     5881 acttcaaatg taaatgcttt ttcaccatat tttttccatt cattatttaa ttcttttatc
     5941 atacatgagc cagcaccaag ctgaaatttg agagagttaa atttgctttt tatgtcatta
     6001 ctttttccaa ggtaaatctt tttagtaata tcatttttta ttatgaatac acctgtgtca
     6061 aatttcattt ctttgtataa ttgttttaat tcacgttttc tatccatgat tttagatacc
     6121 tctctttata attgatatgt aatatgtaag tgtaaaaata tattacatat caattataaa
     6181 gagattaatt ttatatgtaa atagttttta taaatttaat tatgaattag tcatcaataa
     6241 acaagaaatt tagctgtaga aatccattat aaaggctatt ataaatttta atatgctaaa
     6301 aatataaaaa gaatagttga cagtgtagaa aatatggaat aaactaaaag tgtaatagta
     6361 atatgaaatt atatattaca ttgaaaggtg tgaatgatta ttatgaataa aaaaatagaa
     6421 ttaataggga attttgcaag tgattggatt aggtatagtg attatgaata taaaattact
     6481 gaagaagatg aattatatat agttccaaca gaagatgctg tgtttaccat gtataaccca
     6541 tttgatgtag cagatgatat aatagtagat ataattcgca taggacaaga ggcattacaa
     6601 gatatatcaa aagagacaaa agaaatgaaa ctaaagaaag aagtacttga atttgtaaaa
     6661 aagtatggat tattgggttt aatatattca agtgtatata atagagatat agttggagaa
     6721 gaaagagtac tgatgattga aaagaattat attacaaaag agaatatatt gagtacagat
     6781 gaatatgtaa acatgtttat accatttgca agtgatgaag atgtgtattt taaaaaatat
     6841 agaaggggta tagatgtatc aaagagagaa gaatctccaa agttttttgg aaagagaccc
     6901 ttgattttag atttagtatt ttcaaagttc tacactgaac aactagattg gattgtaagt
     6961 tttgctaaag atatgtgtaa gcattttaat caaatttgtg tatataaaaa tacatctaat
     7021 ctattaactg aaagtgttac tattatgtct ggagggttta atcctcaaaa gataggattt
     7081 tctataagcc aattagataa accaattatt gcatgggagt ttgattcttt gaaaacagct
     7141 attgagacta tctatgcctt tgcaattaca agtgaacctt cttctttaaa taaatgcaag
     7201 tactgtggta aaatttatat tcctacaaat tctaaatctc aatactgttc accttcttgt
     7261 agaaattgct caaatgtaaa gaaaagtaga agtagagcca aaaaagataa ataaaattaa
     7321 taaatatatc attgtttaga ttttagtaaa taactactga attaaaagtt gttatagaaa
     7381 attatatatc taaatgatgg tatttttttg ttgagaaaat tgaaaagttt aattgagata
     7441 gtaattttga gttgacaaaa accactttta acactactat tataagtggt tggtaaaata
     7501 atatacacta atttaaatat agcataaaaa acaaaaaaag tcaatggaaa aaataaaaaa
     7561 ggagaattta aaaatgatat cacctattat tttgagttct ataaatcaga atttaaagga
     7621 aatagaaaga aatgaactac ttgaaactaa tatagaatct ggagattatg gtctagctct
     7681 ttctgaatct gatgtaaaag atataataaa ttcgagagat aatactttaa aggggtatgg
     7741 aagaatagaa ttagatataa aagttacaaa acagttaata gaaaatatat atacatcaca
     7801 atatacaaat gtggacaatt atttagaggc tattaatgat atgcaagaaa ttttttatta
     7861 tttaaaaaat gaaactgatg acaagatatg tgatgatgag attatagaaa tgctgggtga
     7921 attttatgaa aaattttcag gcaatatgga caatgtaaga ggagaagcag acgaatttgc
     7981 aaagaaattt aaatttggag aagtttaata tatgatagga gagattttgt atgttaaata
     8041 atttaagtaa tattaatata aacgaaaata atttaataaa gaaccaatat tccatatctc
     8101 tacttaagga atgtctaaat tgtaaagtga tagatgaaag agaagtatat aatatacaac
     8161 aagaaatatc tctaatactt atggatttga ttaaaaaata tacaaatggt caaagcacat
     8221 cagtaaaaac agaagttgct gaaaaactgt tgatttcaat atggtatgct attgatgcat
     8281 atataaataa gcttggagat atagaaaaaa gagttgtgga gttgactgct aagaatgtta
     8341 aaaaagtgta ccttggaggc attgaaatat tagaggaaga gttagttagg ctaaaagatt
     8401 tttataaact aatgatgagt agaaaattgg atactaattc aatagcatat aatgatacct
     8461 tgatggagtt atcaagtttc tttaaaagtt atattgtaaa atttgaagct caggacgttc
     8521 cagtaagtat agattatcca ttggcactag atgatatgga tgttaagggt atttattatg
     8581 tgaagaatta tattgagagt atagatatag aaaatagatt ttgtaaccta tttaagaaaa
     8641 aagatagaga aaaattattt tatgactatg gggtgactta taaaatagat tgtgatgtta
     8701 tacttgtaaa tttatttgaa cttattataa ataattgtat tttttctact attttaggaa
     8761 atgaagtgac taatttagaa atttcaaaat atgagtatga atttttagaa aaacaattta
     8821 aaaatatgta caataatatt actgaagata aagttatagg ctctgaagaa agtaatataa
     8881 ttgaattgat tgaagtagat gatagtttta acactgaagt agatagtaat ttggattata
     8941 atgattttga agaaattaac agagaaatta gaataaataa aaaaataacc ttactactta
     9001 tggaagcaat tgaagtatta ataaaaagat taagcataga agatgaagag gtaataagat
     9061 atattaaaaa atatgaaaag atatttattg aatctgtgct aagctcaata aaaagtaaca
     9121 cttttaaaag tatggtaact gtgagtaaaa ataaaaatga acacttagaa gattatattg
     9181 ttgatgatga aagtaaattg gatgatgaat cgtttagaga gatattcaat gagatattag
     9241 atagtacatc tataattgaa aaaataagaa taataaagga aaatatcaat gctaaaaaag
     9301 actttatcga tattcttgaa tctgaatgtt tatttggaga agagtattta atgttgtttg
     9361 catcattaag tgaattagaa ttggcaatat tgggtagtgt agtattttat gaagatatta
     9421 gaatgagaga aattaatata ttagaattta tgttaaatga gaaaactgaa actactttat
     9481 ggaagataga gtacattaaa tttatgaaga ggcaaagtga agataagata tactccatag
     9541 aagagcatat gaataaaatt aattaacaaa aaattgtgaa taaatagaat gttagtatat
     9601 aatataatct gtaaagcata tcaaaaatac atatatttgg aggaaaatta tgaaagagtg
     9661 tatcataaat aatgttgaag aaataagaga agaattaatt gatttatcta agaaaatatg
     9721 ggaaaatcca gaattagcct ttgaagaaaa gtatgcaagt agcattcaaa aagaatacct
     9781 aaagtcaaaa ggatttaaaa ttgaagaagt agaaaattta cctactggat ttatagcaag
     9841 ttttggagag ggtaaacctg tgattggcat acttggagaa tatgatgctt taccagagct
     9901 atcacaatgt gtgagtgcag aaagaaagcc attagtagaa ggaaaagctg gacatggatg
     9961 tgggcataac ctgttgggtg tagcaggtgt aggagcagtt gtttctataa aaaaattaat
    10021 agaagaaaat aaatttaatg gaacaataaa atattttggt tgtcctgctg aagaagaagg
    10081 tggaggaaag acagttatgt gtataaatgg ctgttttgat gatgtagatt gtgcatttac
    10141 atggcatcct tttgatataa atgcaccttg gagaggtgga agtctggcaa acttatctgt
    10201 aaaatttaaa tttaaaggga taacagccca tgcagctcaa gctcctcata atggtagaag
    10261 cgcacttgat gctgttgaaa ttatgaatgt tggagctaat tatttgagag aacatgttat
    10321 tgactctata agaatgcact atgttataac taatggtggt ggaagaccta atgtagttcc
    10381 tggatttgct gaaagttggt actttattag aggtaaaaaa gcaaaagatg cagaacacgt
    10441 tcttgataga ttaataaaag tagctcaagg agcagcaatg atgacagaaa ctgaaatgga
    10501 gtataaggtt acagatggaa tatatgacta tataccaaac caatgtttga ctgatttagt
    10561 ttatgacaat atggtttttg ttggttgccc taaaaatact cctgaagaag aagaatttgc
    10621 aaaaaagttg tgtgatactc ttactagaga agaaagatta ggtgtagcaa catcattaca
    10681 aaatgataaa tctattgtag aaagctatat acacaaggaa atagttgacg gtgacaaaga
    10741 taaaggacta gctggttcta ctgatgttgg agatgtaagt tatgtaatac cagtggctca
    10801 atttgcaatg gcagcttggc ctgttggaat tgcaagtcat acatggcagt catgttcatc
    10861 agcaggttca aatataggat tttctgctat gataaattca gctaaagtac tggcttgtag
    10921 tgcttatgat gtatttatgg atactaaaat tattgatgaa gcaaaaattg aatttgataa
    10981 atcattagat ggacaaaaat ttaaaccatt ggtataattt tggtaataaa atatttcagg
    11041 ggggaatagc tatgagagaa aaagttgaaa aagtgcttga ggaaaagata aaaccagtat
    11101 tacaaagaga tggtggagat gtagagctta tagatgtaaa tgaaaatggt gtggttttag
    11161 ttagactaca aggggcatgt agtgggtgtc caggagcgac tatgacaatc aaagctatta
    11221 ttgaaaatgt tttggtgagt gaagttccag gagtaactca agtattaggt gtttaatagt
    11281 tagcgtttat taaatgtatg ttatacataa gtatttaata aagaagtaaa aaaaatagtg
    11341 aaacaatata tatgaaaaag tatgagaaag ataataaaac attatagaaa taatgaaata
    11401 tttcatatgt atatgaagaa ataagaaaaa tagtgaagca atatatatat gaaaaagtat
    11461 gagaaagata ataaaacatt tatagaaata atggaatatt tcatatatac atatgaagaa
    11521 atagtaaaac aatatatata tgaaaaagtg tgagaaaata ataaaatact atagaaacaa
    11581 ttaaatattc tatataggta ttaaggaaca tgaaagaaat aatggagtat tataaataaa
    11641 tatgtaaaag tgtgaaagaa ggatgtaggt aaatttgtct tatacaaatt tacctacatc
    11701 cttctttcac actttttatt ttactatcca gccataccaa taaacatacc tataaaatat
    11761 ggaactaacc atatagtcca tacaactata ctaaacttat gaaagaattt tttcttttcc
    11821 tcatcatctt tgtataggac aaaagtagcc caacttgcat gaaaaagcat aagcacaatt
    11881 gcaagaagac ctgtaatact atgaaggttt tgtgataaag cagattttac ttcaaaagta
    11941 tggctgttgg ctatgttact cattgtaaat gttcctaaag tatcaaatat aaaaccaagc
    12001 caaaatataa ttacatgttt cttttttaaa atttttgcct ttctttctcc aaatacacct
    12061 atagtgtaga aaattaaagc tgatgttata aatactattg caagtattaa tttataattc
    12121 ataattatct ctcctttact tttgccaata tatttctaag attttttact aagtcactca
    12181 attcgttttc atcacaattt ttaaaaatat catcaaaact ttcttgcatt ttaattttaa
    12241 aatttgtggc aaattcaaat cctgttgttg taaacttaac gtatgtattt cttttatcat
    12301 tagatttctt gaatttttct atatatccaa tctgttctaa tctgctgatt atgcctgaaa
    12361 ccgtaccttt agctaaagac atttcatcac atagttgtga tattgtaagt tcttgattat
    12421 gagctatcag ttttataact ataatctgtt ggtgtgttaa tccattttct ttaaaatttt
    12481 cttctactgt gtacatagtt ttagaataaa gttcttttaa gagcatggct attctaaaac
    12541 agtcataatt acttttcaat aaaatcacct cttaaatggt ttgcatacaa actaatataa
    12601 tatacttttc ttatatagtc aacctaaaat tttataattt tatagaaaat aatgaagaat
    12661 agaatataaa aattttattt taggtataaa taaaataatt tgatgaaatt ttaacaattt
    12721 ttaaaaagtt tgtttacaca gttaataaat gatgctaaaa ttaactcata gataaatata
    12781 gaaaatttaa ttttgtttaa tgataatgga accacgaagg ttttaacgtt actttacgtt
    12841 tgcttttatg tggttttttt attgcaacaa aggggggttg gggtttgtta aaggatatac
    12901 tgaaaaagtt gttgcagttt attttagtaa tgtttttatt atcttttatt gttttttaca
    12961 tggcaagact tgctccagga gacccattaa tctcttacta tggggatgga gtagaaagaa
    13021 tgagtacaca agaaaaagaa aatgctatga aaaaacttgg tttggatgaa ccaatataca
    13081 gtcaatatat aaaatggatt tcaaatgcat caaaagggga atttggaatt tcatttaaat
    13141 ataaacaaaa tgttacttct gttataaatg atgtctatat aaacactata atattaggtg
    13201 gttcaggata tatacttacc tttgtgctag ccttattgtt aggaatattt tgtacattac
    13261 atgaagataa gctcattgat agaatcatat gcaaattagg aacaataacc aactgtattc
    13321 catcattttg ggttgcctta gtactcatac ttatatttag tataaactta agtatacttc
    13381 caagtagtgg tgcttattca atgggagaag agtccagtat attaagtagg atatcacatc
    13441 taatcttacc tcttacagta cttatattaa gccatctatg gtattacaca tatatgataa
    13501 gaaataaatt actagaggaa ataagagaag attatgtgct tttatgtaag gcaaaaggtt
    13561 taaataatag aactattgtt tttaagcatt gcctgagaaa tataatgcca tcatatatta
    13621 gtataatggc catttcgata cctcatatac taggaggaac ttatgtagtt gaaaaagttt
    13681 tttcttatcc tgggctagga acactttgtt ttgaaagtgc aaagtatcat gattataata
    13741 tgttattagt tttatgctta ataacagggg ctttagtagt atttgggaat atgttagctc
    13801 aaattataaa caataaaata gaccctagaa tgaaatatga tagaggtgat actaatgaag
    13861 ccacaatata gtgattttga aattgtagga gaaaattata ttttagtagc agaagatgaa
    13921 catatagaaa caaagaaaac cttatctaaa aaaattaaag aattaccata tatatcaatt
    13981 attattttat caatcatagt cattggaagt gtattctcat cttttataat gacacatgaa
    14041 ccaacataca tggatttagc aagttctaat ttagctccaa ataaaacttt tttatttgga
    14101 acagactcaa tgggtagaga tatatattct atgatatggt atggaggaaa aatatcttta
    14161 tttataggac tattttccac tgtaatatca actgttatag gaattgttta tggtagtata
    14221 agtggttcag catctgaact cgtagatgat gcaatgatga ggtttacaga aatcatactt
    14281 agtatacctt caatattaat tataatattt gtacaagcta tacttggaaa ttcaaatcca
    14341 gtatctatgt ccatagtaat agggataaca agttggatga atatatctaa gatagtgaga
    14401 acagaagtta gacaaataag aaatagcgaa tacatactag cagctaagag catgggagga
    14461 ggattcttct atgtattaaa gcaacattta cttccaaatt ttgtggcatc aataatgttc
    14521 atggttgtaa caaacatagg cgcagctatt ggtactgaat cgacacttag ctttttagga
    14581 attggtttac caatagaaat tgtttcttgg ggaagtatgt tatctttgtc agaggaagca
    14641 ttactttcaa atagatggtg gattatactg attccgggta tatttttggt tacaacattg
    14701 gtgtgtataa caaatatagg taattatata agaaagaata ataataaaaa atctagtaat
    14761 ttataaatca gcatttgagt actaaataag caaatactga ggtatttgaa atatctattt
    14821 aaataaatgg ggtcaaagct ttgaaaaata ttttataaaa agcaaaaggg ggagcatcat
    14881 gaaattaaag aagttaaaag ttttaagttt agtaatgata cttagtctaa tggcaggttg
    14941 ttctagtgga ggagacaaag ataagaaggc agatacgcct aaagatggaa aggtacttgt
    15001 ttatggaagt aatgactata caagtataaa tcctgcacta tatgaacatg gagaaataaa
    15061 ttcgttaata tttaatggat taacagctca tgatgaaaat aataaggtgg ttccttgtct
    15121 agcaaaggac tggaaatttg atgaggcaac aaatacatat acttttaatt taagagatga
    15181 tgttaagtgg catgatggag agaaatttac agcaaatgat gttaagttta caatagaaac
    15241 tataatgaat ccagataatg cttctgagat agcatcaaat tatgaagata taacaaaaat
    15301 tgatgtggtt aatgataata ctataaaaat tactttaaaa gctccaaata cagcaatgct
    15361 tgattattta acagtaggag tattaccaaa acatgctttg gaaggtaagg atatagctac
    15421 tgatgaattt aatcaaaaac caataggtac tggaccattt aaacttgaaa aatgggacaa
    15481 aggtcaaagt ataacacttg ttaagaatag tgattatttt gtaaaagaac caggattaga
    15541 taaagtagtc tttaagattg ttccagatga taaggctaag gcaatgcaat taaaatcagg
    15601 agaattagac ctagctcaaa taactcctaa agatatgtct aactttgaaa aagacgaaaa
    15661 gaattttaaa gtaaatataa tgaaaacagc cgactataga ggtatattat acaattttaa
    15721 ttctaaattc tttaaagata aaaaagctaa aggattacca aatgctttaa gctatgcaat
    15781 agatagaaaa gcaatagttg acagtgtatt attaggacat ggtgtaccag catattcacc
    15841 tttacaaatg ggaccatata ataatcctga tatagaaaag tttgaatata atccagaaaa
    15901 agctaaacaa gaaattgaaa agctaggttg gaaattaggt tctgatggaa tctatgaaaa
    15961 agaaggtact aagttagctt tcgagataac agcaggtgag agtgaccaag ttagagttga
    16021 tatggctaaa atatgtgcac aacagttaaa agaaattggt gttgatgcta aagctgttgt
    16081 tgtaactgaa acagattggg ctaatcaaga tgctcattta ataggttggg gaagtccatt
    16141 tgacccagat gaccatacat ataaagtatt tggaacagat aaaggtgcaa attacagtgc
    16201 ttactctaat cctactatag ataaaatact tcaaaaagca agagaaacag aagataaaga
    16261 tgaaaaatta aagttatata aacaattcca agtagaaatg actaaggata tgccttatac
    16321 atttattgct tatatagatg caatatatgt tggaaaacca aacataaaag gattaacacc
    16381 tgatacagtt ttaggtcatc atggtgtagg tatattctgg aacatagctg actggacaat
    16441 tgaataatac tgaaattaat tagaaacctt agggataaaa atatatccct aaggtttgaa
    16501 tagcataggg gttgatggtt tttggaacat ttattggagg ttaataatct atctgtaagt
    16561 tttaaagtag aagaaggaga agttcaggct gtaagaaatg tatcttttaa tctaaaaaaa
    16621 ggtgagacat tggctatagt tggagaatct ggttgtggga aatctgtact gtgtaagagt
    16681 ttgatgagga tactcccata caatggatat attaaaaatg gagaggtttt acttaaatca
    16741 agtgatttgg ttaagaagtc tgaaaaagag atggaagata taagaggaaa gaatatatca
    16801 atgatatttc aagaccctat gacatctctc aatccaacta tatcaatagg aaagcaaatt
    16861 gcagaagctg taatcattca tcaaggtata agtaaaagtg aagcaaaaaa gagagccata
    16921 gagcttattg aattggttgg aattgataat cctgagaaaa gatttaaaca atttccacat
    16981 catttttcag gtggaatgag acaacgtata gtaatagcta tagcacttgc ttgtaatcca
    17041 gatgtattga ttgctgatga acctacaact gctttagatg taactataca agctcaaata
    17101 attgatttaa taaaggattt acaacataaa ataggtttgt caataatatt tataactcat
    17161 gatttaggag tagttgcaac tatagctgat agaatagcag ttatgtatgc aggaaagatt
    17221 gtagaaatag gaactgtaga ggatatattt tatgacccta gacatccata tacttggggg
    17281 ttgttgggtt cattacctac tttagattcg caggatgact atttatataa tatacctgga
    17341 atgcctccaa atttattgaa cccaccaaaa ggagatgctt ttgcaataag gaataaaaat
    17401 gcacttaaga tagattatga aaaagagcca ccaatgttta aaattaatga tacacatagt
    17461 gcagcaactt ggttattgca cccagatgca cctgaagtag atgtaccagt tagagtaaat
    17521 tgtggaaggg tgatttctaa tgaatagaga aaaaatactg gaaataaaaa acttaaagca
    17581 atattttcat ttggacaaaa gtactactgt aaaagcagtt gatgatataa gttttgatat
    17641 atataagggt gagatatttg gattggtagg agagtcgggt tcaggaaaat ctacaactgg
    17701 taaaactata ataagactac atgaatctac tggtggagaa gtaatttaca aaggaaattg
    17761 catatcagat aaaaaaacgt acaaatttat aaaaaaagat gtaaacaaaa gtatgcagat
    17821 tatttttcaa gattctactt catcattaaa tccacgtatg acaattgcag atataatttc
    17881 agagccacta aaaattcaag gtatctgtaa aaataaaaca gatagaatga ataaagtata
    17941 tgagatgcta aagctagtag gacttgatag aagttatgca aataagtatc catctgattt
    18001 ttcaggtgga caaagacagc gtattggcat agcgcgagct ctttcagtag acccagaatt
    18061 tataatagct gatgagccta tagcttcttt ggatgtgtct atacaagcac aaatagtaaa
    18121 tttatttaaa aaattgcaac aagaaaagaa tttaacttgt ttatttatag ctcatgattt
    18181 atctatggtg agacatatta gtgaccgcat aggagttatg tataatggaa aattagtaga
    18241 attggcagat tcaaatgaat tgtataataa tcctattcat ccatatacaa aatcactact
    18301 ttctgcaatt cctgttcctg accctagata tgctaagtca agaaatagaa tagagtataa
    18361 ttctaatgga tatgattgtt caaatgaaaa gtcattaagt tggattgagg tttcagatgg
    18421 acattttgta tattcttcta aatcagaaat aaataaatat caacaaaatt taaaagttgt
    18481 ttagtataaa aatacttgaa caggtattta tttgaaatac aaactaaaac cctatttttg
    18541 gagaaatttt aaaactactc caaaataggg ttttttattt ctacttttca aatataataa
    18601 attcaaatat aataaaatta aaaacaagta aagtatgttg ttaagaaagt actataaaat
    18661 taaaaatagt aatgtagaaa aaatgagcaa taatcttatt ttttctacaa taattttcta
    18721 taatttaaag taaggaaagt ttgataaatt ataaccttag ttaaagaata agagtttatt
    18781 aaaaaataaa gtgtgtatag gggttttagt taataaaata ctataatgta ggggagcttg
    18841 taatgatata taaaaaagat aaagtaatga aagttttaga atcatcatat agggaaaatg
    18901 aaaaagggat tacagctaac caattatcag aaaagacagg aattgcaaga aacaatataa
    18961 gtacatattt aaaccaatta ttcaatgagg gtatggttac gaagataaaa ggaagacctg
    19021 tgtattatat ccctgcaaat cttaacctta acaagaatga attgcttgat acacaaagtg
    19081 agttgcttgg cataaaaaaa ggaacaaaag tagaaaacaa aataaaaaaa gatagttttg
    19141 aaacactaat aggtaaagaa catagtttaa gacctataat agaaaaatgc aaggtcgcaa
    19201 tgctctatcc tacaaatgga cttcatacta ttatctatgg agaaacagga gtaggaaaga
    19261 gtatgattgc tagatatatg tacgattatt ctatagatag tggaattaga aaaaataaag
    19321 ctccttttgt aacatttaat tgtgctgatt atgctaataa tgcacaatta cttatgggac
    19381 atatttttgg ggtagaacaa ggagcttata caggtgcaga atcttccaga aaaggtcttt
    19441 tggaaattgc aaatggaggg atactatttt tagatgaaat tcatagacta ccagcagaag
    19501 gtcaagaaat gttgtttact tttatagata agggaacatt taaaagacta ggagatgcaa
    19561 cgaaagaaag agagtctaag gtattaataa tatgtgctac tacagaaaat ccgacatcaa
    19621 cactattaga tacattcaat agaagaatac caatgaaaat agaaatacca tcactgaaag
    19681 ataggacaat gattgaaaga atggaattag tcaaaaattt tttcaaggaa gaatcaaaaa
    19741 gtatttctat ttcaataaaa gtacataaag aaataattaa atcactatta ctttatgatt
    19801 gtaaaaataa tgtaggtcaa cttcaaaatg atataaaatt agctgttgca aatggatacc
    19861 taagatataa aagagataat aaagaaccag tttatataga gaaaaaatat tttgataaat
    19921 ctataaatga agtgagtgat gattatagag agaagtctat taaagcagat gaagttataa
    19981 cacatggaat agaatatttt gtatttacgt cattaggaga agaagaagtt attaactaca
    20041 atgatataaa tattattaat gcagtaaata ctaatcttaa taaatctgta gaaatgaata
    20101 tagcagatgc ttctctattt aataatgtta agtttaaaag catgtgtgaa tcaataagac
    20161 aaattattaa agaagatgaa gaaatagaca taagtgaatc aatatttaag tcaatggcaa
    20221 tttatataaa aagcgtattg gataaaagta gctctacaaa caacatagat ttgaatcaaa
    20281 ttagaagaaa taacagaagt gaatttaaaa cagcactaaa aatagttgga ataattgaaa
    20341 atgaatttga tttattttta tctatagaaa ctgtagcata tattacatta ttcatagtac
    20401 aagctaaaca agatgaacaa aataaaatag tgaataacat taatattata gttgctatgc
    20461 atggagaaac tacagcaagt agtatggtaa aagcagttgg tgatattatt ggaaagtgca
    20521 gtgctatttc tttcgatatg aagttagata aaagctatga tgaagttatt gtagatttta
    20581 aaaatttaat taataatata gacaataaag atgtattact atttacagat atgggttcat
    20641 taaactcttt tgatgaaatt ataaagaaag aaaaaaagtg tggagtaaga gtaattccta
    20701 tggtgacaac attaactgtg ttagaagcag ttcagaaggc caatatggga ttacctttaa
    20761 atgacgtata caactctata actaacacga gaaagtacta ttttggaact aatgaaattc
    20821 aaaataaaga aaatctgtct aaaacaatta ttatagcatc acatgtttca gaaggtgtag
    20881 ataataaaac aagaaaaata ttagaagaaa agatgagtag gtacttagat ggaatagata
    20941 ttatatctgt cccatataaa acagaaaaag atttaagttt aaatattacg aaacttaaag
    21001 aaagtagtaa tattgttgca gtaatcaatg aacaaagaat taatattaga ggaattgact
    21061 atattagcaa aaaagatata gataaggatg aaaatatcaa taaattaaaa aatattataa
    21121 agataagtat aggttatgat gatgtagttg aaggtttaaa gacatcctta aaaagctcta
    21181 attataatag gatatttaaa gatataaaat atgtgtctga tgaattgttt ttagtattta
    21241 atatagaaaa gaaatacgat aaagtaattg gacttatgat gcatttagct ttcatggtag
    21301 atgggttgat tggaaatact agagaaattg aaaagcttga taaagaaaaa acacttgatt
    21361 atcacaagag cctaagcaaa ataaaagata tagtatctca attagataaa aaatataata
    21421 tagaaattaa tgaaaaagag tgctatcaaa tattattaat attagaatat gcagaaataa
    21481 tcgaaaaaga ttaccaatga gtataaaaac ttatttggta atttttttta gtctaaaata
    21541 atattaatat tagacacata taaatatact tagacaaagt atctaagttt tgatgataaa
    21601 aatgattgaa ataacagtgt tttaaagtgt ctaaaaaaac tggcataata cttgcttata
    21661 ttattaaatg agtaatataa ataattaaaa tttaaataaa aaggagtaaa taatatgcaa
    21721 gataaaatat taagagataa aaaggcaaat gacccatggg caagaatgac tacaagaaac
    21781 ggatttagtg cagacgaaat aatatcgtca tttcaaaaag ctataagaag aaatatggtg
    21841 gaagaagctt gtgaatttgc ttatgaacta tatatatcat caccagaatt agaagataag
    21901 ctatggagaa ggatacttac aatatcagtt gaagatatag gaatggggga cccatcagct
    21961 gtaataatca taaataattt aaatcaagta agaaaggaat attcatatgc agatggagac
    22021 agacctttat ttttcataca tgcaataaga tatctttgtg catgtgagaa agatagatca
    22081 agtgatttat taaaaaatat aattataaaa ggatttgcaa tgggtaaagt tccagaagtt
    22141 atggacgtgg cacttgacaa gcatacatat agaggattag aaatgggaag ggattcattc
    22201 cactttttaa atgaagctag tatagtaata ccagaaaaag aagtagataa tgattataaa
    22261 gaaagatact taaaaatatt agaaaaatat aagcaagaag aagttataga tacggctttc
    22321 aagtttaatc attggcagta ctaagaatta gagtaaatat taataagaat taaaataaaa
    22381 taataagaat taaagtaaaa actgatagga attagagtaa gaattggctg ataaaaaatt
    22441 agaaaacaaa agaggttaga tattgtagga gggtaattat gaatatttta ttagtatgtg
    22501 caaatggagc ttcaacaggt gtacttgtgg aaaagatgaa aagtttttgt agtgagcatg
    22561 aaaagttaaa aactaaaact ataaatatag aggcaacatc atttgaaaat ttaaaatcat
    22621 acattgaagc taatgataca gatgtagtac ttgtagcacc acaaattagg tttaaggaag
    22681 atgatgtagt tgaagcttgt aagaattaca aaatagcagt tggtttaata gatactaagc
    22741 attatggtcg tatggatgct ccttctgtta tgaagtcggc aatcgaatta tataaaaata
    22801 gataattggg gggaataaaa atggaagcac ttcaaaataa tttaagaaga tttcttcttc
    22861 caatagcaca aaagattgaa aaacaaaggc atcttcaagc tataaaagaa ggtatgataa
    22921 gcattacccc aataataatt gttggttctt taagtatgtt atttatggca ttaaacaata
    22981 tgttacctga aggaagtgca aaaacattat tatctgaaaa tatggataca ttacttatcc
    23041 ctaataaatt tactatgagt ttattatcta tatattcagc attttttata gctcaggcac
    23101 tagctaaaaa atataatctt aatcatgtag aaataggcat gacagcagtt gttgcacaac
    23161 ttgttgtatg tggacaagta gtagatggtg tattagatac aagttattta gatgcacaag
    23221 gtttatttgt aagtatatta gtagcacttt tagtagttga tattactaag tttatgaatg
    23281 ataaaaatct cgtaattaga tttccaaaag aagtacctag tgtagtaaat aaaagtttta
    23341 gaaatttaac tccaatgata gtatgtataa tgttatttac agcaatagca gcaataacta
    23401 aaaatgtctc aggtcaacca ctaccagcta ttataatgaa tttcttagca ccagctataa
    23461 gcagtgtaga taatgttttt gcagtaacta taatactatt tataactcaa ttattatggt
    23521 tctttgggct tcatggagca gcaataactt caagtatatg gatgccaata gcagctacat
    23581 atatggcaga aaatgcaacg ttaatagcag caggaggaga cccaaaatat gtgtttacaa
    23641 taggttttta ctatggtttc ttgcaagtaa ctggttcagg gataactttg ggattagtgt
    23701 accttatgtc aagaagtaag tgtaagagtt ttaatagtat gggaaaagtt gtgattttac
    23761 catcactatt tggaataaat gagccggtaa tatttggaac accaatagtt atgaacccat
    23821 atatgtttgt accatttgta tttggacctg tattggttgg agcacttaat tttatggcat
    23881 taaaagtagg attagtagga ttacctattg cagaaccacc aggcttttta cctccagggg
    23941 ttgcagcatt tttgatgaca ttagattgga aggcaatcgt attagtattt gcaagtataa
    24001 tacttatgac cttgatatat tatccattct ttaagataat ggagaaggaa gaattaaata
    24061 aaaatgcaga attagctaca acattagatg atgatagctt tgatttttaa caagtcatta
    24121 gaaggagaag gatatggtac ctgaaatgga agaaaaagta tttagtataa tatcagaagc
    24181 aggagatgct aaaagtgatg taatgatgtc tcttaaggaa ataaaaaaag gtgactacaa
    24241 taaagcaaaa caccttttaa attcagcctc agagaaaata caaacagcat caaagcatca
    24301 tttagaatta ctatcaaatg ctatgaatag tgaagatagt gggactgatt ttttagttgt
    24361 gcactctgaa gaccattatt caaatgcatt atttgctcat tctttagtat ctgaacttgt
    24421 agatatattt gagatgatgg acccaagaat taataagaat taaatttctt gtaaatagtg
    24481 cttgaagttt ggctatagtt tattaaatca atagatttaa taaatgaact cccttttact
    24541 ttaaagtact agtatttata aaattattta taaatacagt aaatttttaa atagaaaagg
    24601 agatattatt atggaaaaat tttcagtagt aatagctgga ggaggaagta catatactcc
    24661 agaaatcata ttaatgttgc tagataactt agataggtta ccattaagag caatcaaatt
    24721 atatgataat gatgaagaaa gacaaaataa ggtagctaaa gcttgtgaaa tactaataaa
    24781 ggaaaaggac cctaatatag agtatttagc aacaacatgc cctaaagagg cttatacaga
    24841 tgtagatttt tgtttagctc atataagagt tggaaaactt gaaatgagag aactagatga
    24901 aaaaatacct ctaaaacatg gggtagttgg tcaagaaact tgtggaccag gtggaatagc
    24961 ttatggaatg aggtctatag aaggtgttct tgaaaacata gattatatgg aaaagtattc
    25021 tccaaattgt tggatgttaa attattctaa tccagcatca ataatagcgg aagctgttag
    25081 aaggttgaga cctaattcta gggtaataaa tatttgtgat atgccaatag gtatggaaca
    25141 taatatagca aggattgcag gactcaaatc tcgtaaacat atggatataa gatactttgg
    25201 attaaatcac tttggttggt atacttcaat taaagataaa aaaggaaatg aacttttacc
    25261 aaaattagta gaacatataa aagaatatgg ttttataaat ggtgaagaag gaatgaaaaa
    25321 tgacaagaaa gatagttggt ttgaaactaa tttatttact aaagaaatag taaaaacaga
    25381 tttaactaca ataccaagta gttacttaaa gtactatcta tttccagatt atgttgtaaa
    25441 tcattctgat gtaaattata ctcgtgccaa tgaagttatt gatggaagag aaaaagaagt
    25501 ttttggttca tgtgcattga tagaaaagca aggacattct aagggcagtg ggcttaagat
    25561 aggaatacat gcagagttta tagtggattt agctacagct ctagctttta atacacagga
    25621 gcgtatgtta ttgatagttc aaaataatgg agctatagaa aatatacaag atgatgctat
    25681 ggttgaaatt ccatgtatag ttggaaaaga cgggtatgaa ccattatcaa tagggaaaat
    25741 accaacattc caaaaaggtt taatagaaca acaattagca gttgaaaaat tagtagttga
    25801 tgcttggatt gagaagtctt ataataaatt gtggcaagca cttatgctat ctaagacagt
    25861 tcctagtgca acagttgcaa aagaattact agatgattta atagaagcaa ataaaaatta
    25921 ttggccaaaa cttaattaag aataatatat ttttaaagtt cctacagttt agtacatagc
    25981 ctagttaatg tatttgtagg gactttattt atttacaaat gagatacaag tggcaaacat
    26041 agtgtatttt gcagttagga aagtaggttt agttacttgt tagttggatt aaatttaggt
    26101 acaataattt actatcaatc aatagaaata accagagaag ttgcataata aaaaatttac
    26161 acttttaaca ggatttatgt aggtgtttat agaaataaat aaatatgtac ataaatacat
    26221 aattattttt aagtctaaaa tacaagaatg gagagatggc tatgaagtgg agagattatg
    26281 ctgatgatgt aaatttattt gaggattttg ataaaactat caagcctcta actgacgaac
    26341 aaagaagaaa aaatataaac actttaattg catatttttc aaaagaagtt ccttctaaaa
    26401 tatacaattt atcaaatgat gaaattaagc ctagagatat acttagagga cttttgaatg
    26461 tatatccacc aaaagaaatt gctccagaga tacttaatat gttacataat ttattgttga
    26521 ttgaatgtga agaaagagag ttagtagatg taaatgatat agaagaaata gaggaaggga
    26581 ttgccatatg gagaggtaat ataacgaatt taagagcaaa tgcaatagta aatgctgcaa
    26641 ataacaagtt attagggtgt ttacaaccat tacatctatg cgtggataat gagatacatt
    26701 catgcgcagg tcctagactt agagaagatt gtgacaaaat aataaaaaaa caagggcatt
    26761 tagaatatac tggagatgct aagataacta gaggttattg tttacctgca aaatttgtag
    26821 tacatactgt tggacctatt gtatctggtg gtcagccaag taaagagcaa gaaaagcaac
    26881 tgcttcattg ttataaatca tgtttaaata caataaaaga gattgatgaa ataaaaaata
    26941 ttgttttttg tggaatttct acaggtgtat ttggttatcc aaaaaaagag gcagctaatc
    27001 ttgctgtaag tagagttaga ctatggctaa aagaaaatcc tgaaaaaaat ttaaaagttg
    27061 tatttaatgt gtttactgaa gaagaagaag agaaatatag aagaatattt aaataatatt
    27121 atgtaacaga atcctaaaaa tacttattat ataatacaaa ttcattg
//
LOCUS       DAEPXW010000051        26458 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.052, whole genome shotgun sequence.
ACCESSION   DAEPXW010000051 DAEPXW010000000
VERSION     DAEPXW010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26458
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.052"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(224..1072)
                     /locus_tag="KRM55_002170"
     CDS             complement(224..1072)
                     /locus_tag="KRM55_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH1594410.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(1108..1578)
                     /gene="trmL"
                     /locus_tag="KRM55_002171"
     CDS             complement(1108..1578)
                     /gene="trmL"
                     /locus_tag="KRM55_002171"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBH1594411.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(1772..2989)
                     /gene="nth"
                     /locus_tag="KRM55_002172"
     CDS             complement(1772..2989)
                     /gene="nth"
                     /locus_tag="KRM55_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBH1594412.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDNK
                     DIIEKEEINKKGIDKKDIIEKKEINKKGIDKKDIIEKKEINKKEMDKKDVILEEEINK
                     KGMNKKDIIEKEEINEKEIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKD
                     EKEKKTKKSSSSKATQKTSKETKSKSKIKNESANKKDVNKILDELEKLYPDAKCELNY
                     GTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKS
                     KSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVF
                     RVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIK
                     EDCNYYKELNETK"
     gene            complement(3186..5423)
                     /locus_tag="KRM55_002173"
     CDS             complement(3186..5423)
                     /locus_tag="KRM55_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1594413.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIASQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(5529..6443)
                     /gene="queG"
                     /locus_tag="KRM55_002174"
     CDS             complement(5529..6443)
                     /gene="queG"
                     /locus_tag="KRM55_002174"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBH1594414.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLNYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            7549..7953
                     /locus_tag="KRM55_002175"
     CDS             7549..7953
                     /locus_tag="KRM55_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBH1594415.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(8210..9205)
                     /locus_tag="KRM55_002176"
     CDS             complement(8210..9205)
                     /locus_tag="KRM55_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH1594416.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(9489..10325)
                     /locus_tag="KRM55_002177"
     CDS             complement(9489..10325)
                     /locus_tag="KRM55_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBH1594417.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(10813..11376)
                     /locus_tag="KRM55_002178"
     CDS             complement(10813..11376)
                     /locus_tag="KRM55_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594418.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(11474..12403)
                     /gene="glsA"
                     /locus_tag="KRM55_002179"
     CDS             complement(11474..12403)
                     /gene="glsA"
                     /locus_tag="KRM55_002179"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBH1594419.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(13210..14877)
                     /locus_tag="KRM55_002180"
     CDS             complement(13210..14877)
                     /locus_tag="KRM55_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBH1594420.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(14951..15706)
                     /locus_tag="KRM55_002181"
     CDS             complement(14951..15706)
                     /locus_tag="KRM55_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBH1594421.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(15716..16252)
                     /gene="lepB"
                     /locus_tag="KRM55_002182"
     CDS             complement(15716..16252)
                     /gene="lepB"
                     /locus_tag="KRM55_002182"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH1594422.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(16418..16954)
                     /gene="lepB"
                     /locus_tag="KRM55_002183"
     CDS             complement(16418..16954)
                     /gene="lepB"
                     /locus_tag="KRM55_002183"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH1594423.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(17054..18364)
                     /locus_tag="KRM55_002184"
     CDS             complement(17054..18364)
                     /locus_tag="KRM55_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBH1594424.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(18443..19159)
                     /locus_tag="KRM55_002185"
     CDS             complement(18443..19159)
                     /locus_tag="KRM55_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBH1594425.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            19404..20675
                     /gene="sleC"
                     /locus_tag="KRM55_002186"
     CDS             19404..20675
                     /gene="sleC"
                     /locus_tag="KRM55_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBH1594426.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(21101..21757)
                     /locus_tag="KRM55_002187"
     CDS             complement(21101..21757)
                     /locus_tag="KRM55_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594427.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGVRILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(22869..23279)
                     /locus_tag="KRM55_002188"
     CDS             complement(22869..23279)
                     /locus_tag="KRM55_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594428.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(23495..24877)
                     /locus_tag="KRM55_002189"
     CDS             complement(23495..24877)
                     /locus_tag="KRM55_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1594429.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVILRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(24888..25247)
                     /locus_tag="KRM55_002190"
     CDS             complement(24888..25247)
                     /locus_tag="KRM55_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1594430.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(25452..26231)
                     /locus_tag="KRM55_002191"
     CDS             complement(25452..26231)
                     /locus_tag="KRM55_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBH1594431.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         8659 a         4848 c         2469 g        10482 t
ORIGIN      
        1 aattttttta tatacaattt acaagtacat tttgaaattt ttttaataaa tcttactata
       61 aaaaagtgtg caatagattc ttatctattt acacacttcc ctacaaacta aatctaatat
      121 atcaacactt aatttcatcc aaaataaatc caatttaaca tctcaataat taatattcta
      181 tcctaattta ataaaaaaat aaataatgtc atccaaaaat atattattta ttttttaagc
      241 atatgatacc agtaacacca ggaccagcat gtgcacctat acacacacca atttggaaaa
      301 atctaatttc tttaggtctt aattcatctt gcataacctt agataattgt tctttttcct
      361 taaaatcatc actatatcct atatatacaa tttggtctga taaatcatca ccacaatttg
      421 attttatcaa ttccatcatc ttagaaatta cattcttctt tcctcttact tgagatattt
      481 gcgaaactaa tccatctctt atttcaagaa tcggttttat atttaatata cttcctattg
      541 ctgccttagt agatgatatt ctacctccct tttgtaaata ttccaatgta tctactgaaa
      601 atataacaaa agccttctct tttaattcat ccaaaacagg caatatttca gcaacagact
      661 ttccttcact tgcaagttct cctgctttta ttacaagtaa accagttccc atacaaagca
      721 agttagagtc atatgtatat attttaccat ctacatcatt ctttgccatt acagcacttt
      781 gatacgtacc tgtagctgtg gcagaccctg ctatataaag tatctctcta tcctcatttg
      841 tatatttctc aaaaatttcc ttaaattggg cataagtagc ttgagaagtt tttggatata
      901 cattttcttc tctaagcctt ttataaaatt catctccaga tatatcaatt ctatccttgt
      961 attctctttc ctccagtata actgttaatg aaactatatc tatatcatat ttatctaaca
     1021 aatcttttgg cacgtccgat aaactgtcac agattatctt tagatttttc attaagtatg
     1081 ctcctttctc atttaggctt gttgaaacta cctcatattt gggtatccta tttgtcttaa
     1141 agcctcgtac actacaatag caactgaatt tgataaattt aatgacctag ctttttcaac
     1201 atccaacata ggcactctaa tacaagtatc catatttgct ttcaacaaag gttctggtaa
     1261 tccctttgtt tctttcccaa atactataaa acaattttct tcatatttca catctgaatg
     1321 tgactgttta gcctttgttg tagaaaaaaa gtatttacta tttggatact tttcttgtaa
     1381 ttcttcaaag ctatcgtaat attgtatatc agctatatcc caatagtcaa gcccacatct
     1441 ttttaggtgt ttatcatcca atgaaaaacc cagtggtttt actaaatgta aagttgaacc
     1501 tgttgctgca caggttctta ttatatttcc tgtattttga ggtatttctg gttctactaa
     1561 tactatattt aatgacattt taatcctccc taagtatcgc ttttatttat caaattttat
     1621 tttataaaca gaataacaat aatattatac tattatataa aataatgtta ataataattt
     1681 ttatttcatg tatataatag ttttttatct aacattttca caagtattat tatatcagaa
     1741 aatccctctt gtacaactta ctttctaaaa gttatttcgt ttcattaagt tctttataat
     1801 aattacaatc ttcttttatt gggcaacttg cacattctgg atttctagct ttacacattc
     1861 ttcttccatg aaaaattaat acatgatgtg agtgtgacca tctttctttt ggtatagctt
     1921 ccataagtgc aaattctgtt ttttgaggat ttggctcgtc cactattcct attctattgc
     1981 taactctaaa tacatgagta tctacagcta ttgctggatg attaaaagcg ttactaagta
     2041 caacccctgc tgtttttctt ccaacaccag gtaattttat aagcttttct aagctatcag
     2101 gtacttcacc atcatataat tcacatagct gttcagatgt atcctttatt ttttgagact
     2161 tgcttttgta aagaccacaa ctctttatct ctttactaat ttcttcaatg ctcaaattag
     2221 caaagtctct agctgtgttg tactttttaa acaactctga agtaacttta ttcactctta
     2281 catcagtaca ttgtgctgat aaaatagttg ctatcaaaag ttcaaaggct gtcccataat
     2341 ttaactcaca tttagcatct gggtacaatt tttccaactc atctaaaatc ttatttacat
     2401 cttttttatt ggctgattca tttttaattt tagacttact tttagtttct ttacttgttt
     2461 tttgtgtagc cttactagaa ctacttttct ttgttttttt ctccttttca tcttttttag
     2521 tacttttttt acttactttg atactttttt tatcttcttc aatatccata aaattctcta
     2581 tatctttctc atcaattatc tcatcttttt taccaatcat tttatctatt tctttttcat
     2641 ttatctcttc cttctcaatt atatctttct tattcattcc ttttttattt atctcttctt
     2701 ccaaaattac atctttctta tccatttctt ttttatttat ctctttcttc tcaattatat
     2761 ctttcttatc tattcctttt ttatttatct ctttcttctc aattatatct ttcttatcta
     2821 ttcctttttt atttatctct tctttctcaa ttatatcttt attatctatg ccttttttat
     2881 ttatctcttc cttctcaatt atatttttct tatccattcc ttttttattt atctcttctt
     2941 ccaaaattac atctttttca tttatctctt ttagatttac atttttcata attatccccc
     3001 ttcaaaatac caatttataa aatgctattt ataaatagtt taatcatatc aacaaaaaat
     3061 aaacatcaat atataaaaca tacaaaataa gaatttaatt tatatatatt tacaaaaaaa
     3121 gcaaaaacct attaaagttc ttgcttttta ttatacataa atacccatta aattctataa
     3181 taaacttatt cttttgacac agtttgtatc ttgctgaaag atattaattt ttcttttacc
     3241 aatttcttta tttcttcaaa tttaacatct gtcaatatct ctatagcctc ttctactctt
     3301 tcaacagtat atatcttaaa ttttccatct cgcactgcat cattaacttc atctgataaa
     3361 acgagatttc tttgattttt tctaggaatt atgacgcctt gctcaccatt taacccttta
     3421 gttttacata tagaataaaa tccttctatc ttttcactta taccaccaac tacttgtata
     3481 tcaccctttt gatttataga acctgtaaca gcaatatttt gtttaattga tactccacta
     3541 agagatgata atagtacata taattctgca gaagatgcac tatctccatc tattccacca
     3601 taattttgtt caaaacaaac atatgcattt agtgacaata gtaaatcctg tgcaaaattc
     3661 tcagaaagat agccacctaa tataagtact cctttgttat gtatagagcc actcatattt
     3721 acttctcttt ctatatttac tatgccttta cttcctgggc tagtggtcgc tgtaattctt
     3781 gaagctctac caaaagagta ttctcctgta cttaagactg acagaccatt tatcacgcct
     3841 acttttcttc cctctgtttc tattagagta aatccatttt caattgattc atccatatgt
     3901 gtttccactc tattgattct ttttctcttt tcacttattg cttttttaac atcacactgc
     3961 tctgtatact ccgaatttct aaactctgca taagcacttc cttctattac aacttccatt
     4021 attttattaa acttagttga tagtttttct aaatcgccag ataatctagt gctaaattta
     4081 ataacctctt caactgctga tttagtaaaa tgccttaaat tattcttatc acattgggat
     4141 gctataaatc ttgctattcc ttcttcatta tcttcatttt tatccatttc actatcaaag
     4201 tctacaaata ctttaaaata tttttcaaaa tcttcatcat atctatataa aatatcatat
     4261 atatagtggc ttccaatcag tactaattta acatccaatg gcatattttc tggtttaatt
     4321 gctgtttgtg tttccaatat tactttttta gtctgcaaag tctttttaag aatttcccaa
     4381 gacattgtat attttagtaa ttggtctgca taaagtacta aataaccacc attagcccta
     4441 tgaaatgctc ctgataatag ttttgtgaaa tcagtcttta tatttccatt tgcataatca
     4501 tactctgcct ttccaaatag atttgctgga cttgggttta tctctactac aacaggtgct
     4561 gattctttat tctttgagct tccattgtct acaaataggt taattttata tttaataaaa
     4621 tgctctttat catacttatc ttttaactcc tcttcatcta aatagaataa atacatatat
     4681 tctattatat ctttctttat attttccaga taagtttgaa tcttatcata attttcatat
     4741 ttttcacaca atctcttgat atgaggttct actacaagtt tagctatctc ttcttcaagc
     4801 tctaacactg ctttttcagc tatttcttct aagtttctaa ttttatatac gacctgtatc
     4861 gccatatttt ctagttctct tttagctttg taaaactctt catcagactc atcactttca
     4921 tcttcctctt ctttcaaagg gataaaaact attcccattt tactctgttt taatttaaat
     4981 cctttttctt ctccatattt cttaatttgc ttcaaaagca tatctttttc tatttcatat
     5041 tcatccagaa gtttattttt ttctatttca aaattttcac tttcaaacgc atttttaaaa
     5101 tcttctaaaa gactttcaat taatttctcc atatctttct taagttctct tccaaacccc
     5161 ttttctaatt caactataat aggctctcta gggttttcaa aattatatat ataacaccaa
     5221 tctttatgcg tatttttttt ggatgcatac tcatttaaaa cctttaaggc ataagtactt
     5281 ttaccagttc caggttcacc agctatatat atgttgtacg ctggattatt tattttcaac
     5341 cctaattcca tagcttctac agctctttct tgacccaata tataatctag tggatttatt
     5401 tcagatgtat tattatattt caatattccc ccacctcccc atatttaact ttaatgatat
     5461 aatatgactt ttacacaaca agtgttaaag taaatacaca ttaaagtata tgaaacagac
     5521 tcttattatt agtcatcata cttatctaaa attatttcca tatttctctt tattatattt
     5581 ctccctctcc agctaaaagc tctatctcca tatctccttt taaattcttt atttgaaata
     5641 ttttgtatct catcataatt caaataatct attatatttt ctttaaattc caaaatatga
     5701 gttgttggta tttcaacatt atgtggacat acttcttgac aaatatcgca tccaaatacc
     5761 tttttgccat tctttaaaac aactttttcc ttctctgaca aatctccttt tttttgagtt
     5821 atatatgata aacatttttt ggggttcata tcataatttc ccaatatagc atttcccgga
     5881 caatatttta cacacttacc acatttaaaa caactttttt ctagtggttt atcttcttca
     5941 aatttataat tatttactat ataccctata aatacataag aaccatattc atcagttatg
     6001 atattattat ttattccaaa atatcctatt cctgataaat aagctaaata cctgtcaact
     6061 aatggtccat tatcagcaaa taacttgtat ttaaaatctg ttactgtttt agaaatataa
     6121 tcacaaattt gttgtaaaaa gtcctttact acaatgtgat aatcctttcc atgacaatat
     6181 tttgataaat ttgaattttt attcttttct tgtctattta tatgatatgg aaatgcacag
     6241 actattatag agttagcatc cttcattata tgtcttgggt taattctgtt ctcaattatt
     6301 ggttcttcca taccagttaa ataacctttt tgttgtctgt ccttaagtat cttttctaaa
     6361 ttatcatact tatctacccc tgctactcct acacagttta atcctattaa attacaaaat
     6421 gcttttaatt ccttattatc cataaaatta ttccttttta atctaattga ctttttaaat
     6481 ttatttaatt tttttagtct ttttaacctt ttctagctac taactctttt aaatacttaa
     6541 tctttttatc tattcaattt tcttacctac ttaaatcttt tagatacttc gtctttttat
     6601 ctatttaatt tttttaccta ctaactcttt taggtacttc gtctttttac ctatttaatt
     6661 ttttacctac taacgctttt agatacttaa tctttttatc tatttagttt tttacctact
     6721 aactctttta gatacttcat cttttttatt tactaactct tttagatact tcatcttttt
     6781 tatttactaa ctcttttaga tacttcgtct ttttcattta cttatttaac ttttttatct
     6841 acttaactcc tttaaataat tagtcttttt atctatttaa ttattttacc tactaactct
     6901 tttgaatact tagtcttttt tatttattta atttttttat ctactaacgc ttttatatac
     6961 ttaatctttt tatctattta atttttttat ctactaactc ctttatatac ttagcctttt
     7021 tcatttactt atttaactac taactctttt agatacttag cctttttcat ttacttattt
     7081 aactttttta cctacttaac tcttttagat acttagcctt tttaatctat tcaacctttt
     7141 ttacccactt aaccttctta ccttttaata taaactctaa aacttcaaat atcattagtt
     7201 atattttgac attctttcta tagttaagca aaaagattga ttttttctta taattaatat
     7261 cccatttaca ttgccattta ttaagtcttt acttgactta tatggatttc tttttactct
     7321 ctttactaaa ctatacttat taatattatg aaggtcttat aatagtctaa tatgaatatg
     7381 tccatcatat atcaaatttt aaaatttgta agcaaaatac ttatcttata ttactacatc
     7441 taaagtagaa aattttacaa acaagctctg taaaaacact ttaaataaca atttgctttt
     7501 aaatcatata cagattataa taaatactgt ataaggatgg tgaaaaattt gattaaaata
     7561 acaattccag gtagacctat tagtaaatct aattttaagc ttcataacat aaatggtcaa
     7621 gcatggatgc cttcaaaggg aaaatattct aagtatcttg catacgaaaa catgattgca
     7681 ggttttataa accaacagta tcaaggggaa actgttgaag aaaatctaat aacagtcttg
     7741 aaattattct tcccaaataa gagaatgggg gatttacata attatccaaa aagtatttgt
     7801 gatggtattg aaaaaagtgg aataataaaa aatgataaac aacttaagcc agtactttta
     7861 tttgatttta tagataaaga taaccctagg gttgaaattg aactttatcc agtatctaaa
     7921 tacgatatat cctataatat ttttgaaaaa taaagatttt atgtgttatt cgacattata
     7981 ttgatactcc agtatttgaa actatactaa tacaacaata ataattgtgt tatgtctata
     8041 ctcaaacaaa tgtttttaaa aagcattaag caaatattta ataagtatta aacaaatatt
     8101 aaatttatat aatagctata actatgtaaa tttaatattt gtatataaga ccacatctaa
     8161 taaaaagaaa tcggagtaaa tttaatacac cgatttcaat aaataaaatc tatcctagct
     8221 tttcaacaac agtcttaagc atttctctta taggaagttc atatggacat ctactctcgc
     8281 aaagcccaca gtcaatacac tcagtaggtt taacatccat aacctcatat ttttctttag
     8341 cccactcttt taatccatat ctagtataat aaccttcaca taaaaaactc aatggtatat
     8401 ttattcctac agcacaaggc atacaatatt cgcatcttct acagaatttt ttacctaaag
     8461 aatttcttat ttcttcaatt tccttattat ctttttcatc tagcacaaga ttttcaagta
     8521 cagcgacatt ttgtctaacc tgttcaacac tctccatacc tggtataact acatctatgt
     8581 aatctttaga tagtatatat ttaatagcca gtgttgcatt gtctaaagca cctccagcta
     8641 aaggtttcat tactattatc ccaattcctt tttcatgagc ttttttaaac acttcatctg
     8701 cttgtccttc aactatattg taagggaatt gtatagtgtc aaattttcca tcttctatag
     8761 ctttttctat agtatttaaa ttgtgactag ttataccaat atgttttatc ttaccttgct
     8821 cctttgcctc taaaagggca ctataagcca ttttatcttt aaaaagatta tcatactcct
     8881 cttctttaac attatggaat tgatataaat ctataaaatc agttttaaaa ttatttaaac
     8941 ttatttcaac atctctcttc attgaatcat aatctctgga catactttta gtagctaaga
     9001 aaaatttatc tctttttcct tcaatggcaa ttccgattgc ttcctcactt attgtatacc
     9061 ctcttgcact gtcaataaag tttattcctt gtttttctaa ctcatttata actaagttag
     9121 tatcatcttg agtaatcctt tgtattggaa tgcccccaaa gccaactctc tttattttca
     9181 tgttagtatt gcctaaattt ctcatatctt tccccaccta acttttaata attttttata
     9241 taatataaat atgtcatctt taattataca acaaattatg agaatctttg caatatattt
     9301 acatactatt cataatataa ttatatttta tatcagtcta ttcataatat aatcatactt
     9361 tatacccagt taatttgtat acaatttttg ttattcctat ccattaattt aaattatcac
     9421 atttcatgat tgtatctcca ccctaattat gttgagggtg gagtatttca catattttta
     9481 ataaaggttt atttactaga tagtatttct tttatcattt taagctctct cttgtgacct
     9541 tcatcatcaa aaggagtttc taagaaaaat ggtaaatgtt ttagactagg atgttccata
     9601 aaatcaatta atgcttttaa tcctatcttt ccttccccta taggagcatg tctgtctttt
     9661 ttgtctccaa atggcatcat actatcattt agatggacag ttttcaatct ttctatgcct
     9721 ataaccttat caaattcttc caaaacccca tctaaatcat tcactatatc ataaccagct
     9781 gaaaaaatat gacatgtatc aagacacaca cctatttttt ctttatgctc aattttgtct
     9841 attatacttt ttaattgctc aaatttaaaa cctatttcag ttccctttcc cgacatagtt
     9901 tcaagaagta tagttatatt ttcatcaccc tttatggcat tgttcaatcc ttttactatt
     9961 ctatctatac caaaatctac accaccacct acatgacttc caggatgaaa acacatgtat
    10021 tcaattccta atgagtccat ccttcttata tcctcatcta tcacccttgt tgcaaattcg
    10081 tatacatcat cctttgtacc acccagattc atagtatatg gtgcatgtgc aagcagtggt
    10141 gcaaaattat tttcttttct aatttcttga aatttaatta tatctttttc atcaaattct
    10201 ttagcatttc ctcctcttgg atttctacta aaaaattgaa atgtatttgc accaatatat
    10261 acagctgtct cagccgcatt agcaaagcct tttgctattg aaagatgtgt tcctaattta
    10321 atcatattaa tctcctttta tttgtactac aacttgtact caattttaat tttgaactac
    10381 tccaccttaa ctacatttag ccaacatatg aagatggaga ttcctatttg atagtacttt
    10441 ttcactaaaa attcgtaagc tctaagggat gttctatccc aactaatctc attcctcttt
    10501 taacatattt ctagcattga tttaatttat attaattttt aattttaata tttacacttt
    10561 aattataccc attttaatca atttcaaata ttataatctt acatactttg tatattatct
    10621 aagcacttct tagatagtgt atacatctta cactatacat attatttaca aatacaatag
    10681 gtataaaaaa acaaaaaaat agagattaaa aatcattgtt ttacccatac caaaaactat
    10741 tttttgatta ttaagtaaat tttgatgttc aatctctaat attatatctt taattaatcc
    10801 ataattaatt ctctaactag gacattcctc ctcaagagta ggaactataa ccatagctat
    10861 atcatactta gaaccttcaa cattgtgttg tcttttattt aaaatttcat ctatctttga
    10921 cttcatagtg tcactaagtt caactaattc atcatgagta agagaaatat catgataatc
    10981 aactatattt tcattttcta aaacatcttc ctctgctgcc ttataaaaaa cttcactcat
    11041 attttcaaat tttgatatgt acaattcttc tttttcttcc ccattgtcta aagaaaaatt
    11101 aagtatccta ttccctataa ccacattttt tgcacttgga taatagtatt tttccacaat
    11161 ccccgacttt attttttcct caactaattc taaaatacca actttgtata acatttttat
    11221 atggtagttt atttttgcat gaggttcttc caataattga gataattgtt ttgctgacaa
    11281 tggcgatttg tcaaatgctt ttagaatatc tattctacgt ggatgcgcaa tagcctttat
    11341 gcactccaaa tctcgtaata ccaatacctc tttcattgac ccctcctaaa aaatttattt
    11401 aattcatatt tctttacaat ttaattatat attaaattat atgttgttgt caaaaaaatc
    11461 ctttcttaat attttaaaaa atatttaatt tgagtttatt tgacaactcc tctaaaactt
    11521 taactcctgc gacgctgtta ccttttttgt caagcgcagg tccataaaca ccaatcccca
    11581 tgcgtcccgg cacagaagcc attataccac ccccaactcc agattttgca ggaatgccaa
    11641 ctttaatagc aaattcccca gaagcatcat acattccaca agtcatcata aatgtcttga
    11701 caatcctaga aaccatttca ctcattaaat gctcaccatt ttctatatct actccataat
    11761 ttgcaagatt tattccaatt ctcgctaaat ctacagaatc tatctcaatt gagcattgtt
    11821 taaaataaag gtctagaaca tcttctacat tccctctgat aaatccatca cttttcaata
    11881 agtaagccat agctctgttt ctatctccag tcattttttc agacttatag acatcatagt
    11941 ttattcctat attatcattt tttgctaact ttctaaagaa actaagcatt ctttcttctt
    12001 tttcttctaa acaactccca tttataaggg aagtggttac tatagcccct gcatttatca
    12061 ttggattaca gggttttttt gtgtcattaa tttcaagttt cattattgaa ttaaatgggt
    12121 ccccacttgg ctccattcca acgtttgaaa aaacgtcttc ccaatcatta tccataagtg
    12181 ccatagcaag cacaattggt tttgaaatac tttgtatagt aaactttgtg ctacagtttc
    12241 cagcactata aagattattt tcgctatcta tgatacaaat tcctaaatca tttcttctag
    12301 cgttttttaa ttctggtatg taactagcga cttgtccata attagtatac ttcttattag
    12361 aacttataat ttcttttaat aatgtctcat ctaacgtatt catatgcacc tcttatatta
    12421 tgttatatat tctattttag cacaagttta tactataata aaacaatgtt aaaaaaaatt
    12481 atactttaaa attattttct acaagaatca attcattttt caaacaattt aaatagttta
    12541 aatagcttaa taatttagta attcaataat ttaacaacct agcaatttag taatctaata
    12601 atccagtaat ttaacaacct aataatttag caatctaata attcaataat ttaacaacct
    12661 agtaatctaa ctatctaaat aatccagtaa cttaacaacc tagtaattta gtaattcaac
    12721 aacctaataa ttcaataatt taacaaccta gtaatctaac tatctaaata atccagtaac
    12781 ttaacaacct agtaatttag taattcaaca acctaataat tcaataattt aacaacctag
    12841 taatttagca atccagcaat ctaataatcc agtaatttaa atttttataa caccaaaaat
    12901 ttctaaccca acacctttta ctcttttact cttttactct tttactcttt tactctttta
    12961 ctcttttact cttttactct tttaaaaaat aatcacataa actaacaaaa tattaaacaa
    13021 aaaagtaaaa tttaaaataa aaagcttgct tcatacaaaa gtataaaaca agccttttta
    13081 tatatcaact caaactttaa aatctgtatc aatttaattc tccactttac acttaatata
    13141 cttaacataa accaataaca ctacttgcta tgccatttaa tcttcataaa acaatctata
    13201 atacacacat taatcaacta ttttacttcc tccaataaat tccctaagaa ttgaaatacc
    13261 tggtatgtca gaagtatcgt ccaattcaac aaaatactgc aaaaacttta gtaatctagt
    13321 agcttcaata tgtgcaggat tatcttcctt tatctcttcc aacaaaggtt tcgcaaatcg
    13381 ttttaaaact gccaattcat atacacaagc agagttaaat atagcatctg cctcctcttg
    13441 gtacgggaat atattcttct tttctcctct tctaactgat gcccattgta aaatagtatt
    13501 atcagcacta tatcctctaa aattatagtc tctaacaatt cttcttatca ttctcaaatc
    13561 agcagtaggg attcgattat ggtcatccaa atttatttga gtaagggcac ttatgtatat
    13621 cttaaattta tcttcatctg gtatagatga tgttaaaata ggatttagcc catgtatacc
    13681 ttctaatata attggctgat ttgaatctat ctttatcttt ttaccagtgt attctctctt
    13741 accttcttta aaattgaatc ttatatcatc aatttcttca ccagctaaaa gtttctttaa
    13801 gtctaagtta aacttctcta aatctattgc ataaattgat tcaaaatcat aatttccata
    13861 ttcatctaaa ggagtatgtt ttctatctat aaaataatca tctaaagaaa ttgaaatagg
    13921 atttaaatta tttactctaa gatgtattga taatctgtga gcaaaacttg tttttccaga
    13981 tgaagatgga gctgctatta aaactactct cttattgcca tcctttatca tatccgctat
    14041 ttgggataac ttcttttcat gcaatgcttc aaatgtcctt attatatctc catattcatt
    14101 gttttctatt attttattaa gagatactac cttgtcaatt cccataagtc ttgaccattc
    14161 ttctgcttca taatatacac ttgatagctt aggttgaggt acaaatttca taggaagagt
    14221 cttatcttct tcactaggtc ctaaaattat aacgcctcca ttataaagct taatatcaaa
    14281 tgattttata taaccagttg atggcaacat ataaccataa aaatggtcta tatagtttct
    14341 acacttatat actttagcac tatcatactc tttgtatttc aaaagctctg ccttttcata
    14401 catttcatta ttttcaaaga tagaaatagc ttcatttctt gtaacttcaa ttttttctat
    14461 aacataatcg ttgtttacta tctctttcat cttgtttttt atattttcaa catctgcttc
    14521 tttaagcttt ctatctatat gaacttcaca atatagccca tctgatagtg aatgttctat
    14581 tgtaactctg ctatcccaaa agatttctct acatgccatt acaaatataa atgacatgac
    14641 tctaaagtaa actctctctc catcttcatt agtagtatct aaaaaattta tctcacaatc
    14701 cttcttaact ctacaattta gctcttttag tttattgtct acaactgcaa gtgttatata
    14761 acccttatgc tcatcacaaa attcttttgc tatatctccc aatctgattc caggggaatt
    14821 ttcttctaat gaatattcct tatcttttcc ttctattttt aagtttattt ttttcacttc
    14881 aacatctcct tccttttgat gaatataaat tttaattaat gaggcatatc aacaagataa
    14941 agagaggtat ttaaccctct cctacaatat tattcaattt acttatagta tcttcaatgt
    15001 cttcgtaatt tatttctaat actaaatatt ctgcatctaa tgttaagacc tctttaatcc
    15061 cctcttcaga taaaattcct cttcctatac caacatgtgt atcattgata ccatcattat
    15121 cacttaagtg tatcagtctt attttatcct ttaagttctt tacataagca tcctcatcaa
    15181 ttaaacagtg tccagtatcg taacaaaaac aaatcttaga atttttaatc ctcttaaata
    15241 tatattcaaa atcataagat atatttccaa tatttgaaaa atccccacct tttgaataag
    15301 tattctctat acatacatat gaatttgtat ttaatttatc taaaaaatcc acactatttc
    15361 ctaaatattt gtctctattc tttctaactc tatttgtcat aacatatccc aaatgaaggt
    15421 taaaatacct taaatcaaat ccttttagtt caaattctat cttctcaata aaatttatcc
    15481 atgaatttcg tatatactct atgttttcgc aagtatttaa ttccataggc aagtgtatcc
    15541 ctatagataa tcctaactta gaaattctct ctttatattt acataactca ctacattcag
    15601 atatattgtc aattccaatc tctaaatgag ttatttgctt tatactctca caaatgttta
    15661 aagcctcctc aatattaaac aataaggacg ctataccaac tgccatacaa atcacctact
    15721 caaaaatacc tatatctgta aaaggaaata ctcttaaaat aacttttcct ttaatatttt
    15781 cttcatctac taatcccact tctttatatc tactgtctaa actaacttct ctattgtctc
    15841 ccatcgcaaa tacttttccc ttaggaatca ccatatcaat atcgccttca gtataattat
    15901 catgtatata tgaaacttca tttaataact taccatttat ataaacctta gaatccttaa
    15961 tttttagatg gtcaccagga acacctataa ccctttttac aagctctttt ttccttccat
    16021 tctcttgtaa taaatcagtc ttaaatatca ttatatctcc acattttggt tctgataact
    16081 tatatgtcat cctgtttgct accaaataat catgtgattt aagtgttggg tacattgatt
    16141 ctccatttac taatgttggt tttataaaac gagttataat aaatgcaaaa aaaagtgcag
    16201 taataattat ttttatccac tctacaatct cttctttaat agtttcattc attcacaaat
    16261 tctcctttat agttatatta tctttattga taatgtctct taaacactat cttttagata
    16321 agtctactaa ataaggtgtt gtctttttta tatagacaac tattgtgtat ggtctggtga
    16381 tttcagctaa tcagcgattg ctccaaattt tatatgttta gtcaatagtt cctatcttag
    16441 aaaatggata caatctgact agaacctttc ctaaaatggt atgctcgtcg accaatccaa
    16501 cctcatcgta tctactatct aaactttttt ctctattatc tcccattgca aataattttc
    16561 cttctggaac tacgatatca atatctccat cagtacgatt attatgtata taggaagtct
    16621 catctaacaa cttatcattt acatatacct tggagtcttg tatttttaca tggtcaccag
    16681 gaaccccgat aactcttttt actaaatctt ttttctttcc attttcctct gttaagtcgg
    16741 ttttgaatac tattatatct ttgtattttg gctctcctac cttgtacgca attctgttaa
    16801 ctatcaaata atcacgttca actaatgtag gatacattga ttctcctttg actattgttg
    16861 gcactataaa acgagttatt gcaaatgcca aaacaagagc tatgacaatc acttttatcc
    16921 attctacaac ttctttttta actgcttcac ccactaaaat cgtctcctct gtgttaaata
    16981 ttaagtcaat ctacagcaaa ataatctacc ataaacctac aatataaata ttatacttct
    17041 tttttctaat agtttaaaat acttttctaa gacctttagg ataatgattc ttaattacac
    17101 cagaagattc ttttccccaa cctaaaggta ttccttcaac cgaaaccaaa acccatcctc
    17161 tactatcatt agaatttaca acatcccctt ttaaatattt aagaattgat tcactctgta
    17221 cactgaagtt ttcaacattt tttacatctt caacttttaa gtaatgagat agtgcatgag
    17281 aaggctcaaa tctattcttc tttaaaaccc ctaaatgcaa accatatctc aatactttta
    17341 gttttttcgt atctggatat atttcaggaa gtaggtacaa attttctcct cttaaataaa
    17401 atttattttt tttattacta taaaaatcaa cctttaaaaa tttcttttca aactccctat
    17461 aatcctttat ttctttatct aaatttttta tttttaattc tttgacatta cattcttctt
    17521 cttctaattt ttttattttg gcaacaaaat gaccttctcc ctttatctta tgaggccata
    17581 atctttccat ttcaataagt tctgcatgtg gatattcact gataaactca tttataacat
    17641 gctcattttc ctcccttgaa aaagtacaag ttgagtaaat taaaatgcca tccttcttta
    17701 acattttata tccatctctt ataatctctt tttggatgga ttgacattct actacctttg
    17761 cataactcca atctgatatg gcaacctcat ccttcctaaa cataccttgc ccagaacaag
    17821 gtgcatctat aataacctta tcaaaatacc cattaaacgt ctttcttaag ctattagaat
    17881 cggtgtttgt tataatacaa tttctcgctc caaatctctc taaattttcc cctagagcct
    17941 taattctact agcattaatt tcattagaaa ccaataaacc tgtatcgttt agcttagata
    18001 gtatatatgt agattttcca ccaggagcag cacacatatc gagaactttt tcaccctctt
    18061 taatatctgc ctttggtatt acactcattg cagaaggctc ttgcaaatag tatgctccag
    18121 cctcatgcag tggatttcta ccaggtctgt caattttatc atcataataa aaaccttctt
    18181 ctgcccatgg tatttgattc aaatcaaaca actccaaatc aaataatttt ttcttgtcaa
    18241 tttttaaagt atttattcta agcccagtag tcttactttc ctcataactt tttataaaat
    18301 catcatattc atcttttagt atttcttcaa tatcttctaa aaattccttt ggtaattctg
    18361 tcaaatctat aatccccctt caatctgctt tacttgtgtg tcatttatta tactttaatt
    18421 atttatgtct ttcctttaaa ttttatttct tcttcttttt cctaagatta ccgaaaaaca
    18481 cttttttaga gtgattcata tatttctcaa gtttatcaag atttatcttc cacaaaatta
    18541 ttacataaac tataagtaat ataatagccc atctatattc tatcatcaat atgaaatcaa
    18601 aaactccatg taataaaatt ggaattaaca ctgccataaa caaatactca cgtcttttat
    18661 ttttatttcc ctcaaattta tacttagaaa tatagtagcc catagtaatt gcaaacatta
    18721 catgagctgg tatagagata actgccctat taataccaac ttgcagtgct agatttctac
    18781 tttcagaaaa aatataaacc atattttcaa ttgttgcaaa tcctaaagct aaaaatacag
    18841 agtaaataat accatctaac ttttcagtaa agtgtttttc tttaattagg gcaggaatca
    18901 gtatcagagc ttttacacct tcttctacaa gtcctgcaac tacaaatgat acatatatta
    18961 gttctgaata cccttcaaat acattaaact tcatcagtaa attttctaaa agtataatta
    19021 taacacttag aaaagcacct attaaaaaaa atttaattag atggattagg ggttctctac
    19081 aatatctatc tttagacctt atccaaaaca tccctatcaa tataggaact attgctaata
    19141 aaaataaatc tagcttcata gattattttc ctttcaaaat ttttgattta tttatgattt
    19201 atatcatcta cttattttta acttattcgt gttttaaata catactaaaa tatacattaa
    19261 attattttaa attatttaaa tacaaatata ctcaaatact caaaaaaatt taaatttata
    19321 tctatattat ttaacaaatt tcaagctata ttcatatctt gaaatataag ggaactaaat
    19381 tcatttaaag aaagggtgat ttgatgcaag atggtttctt aacagtaagc ataattgatg
    19441 ctactaacaa tagacctatt caaaatgcag tagtaaacat atattcaatg tctaatggta
    19501 gccaaagctc atcaacttta taccaaaacc taagaagtaa tgaatctggt caagtgactg
    19561 gtttagtatt accagcacca gatgtagatt actctctaca accatctgat gttagacctt
    19621 atagccagta tatagtggaa gccatagcag atggatatga gacagttgtc atagaaggaa
    19681 cacagttgtt agctacaatt gaagcaagac aaggagttcc catgtctcct agaacaagaa
    19741 gtaagcgttc tttctcaaga caaagtgagt tgatttttga cataggagaa catactctat
    19801 atggtactta tcctcctaag attccagaaa gtaacttaaa accattacca cctcctactg
    19861 gtttcgttgt attagataac cctgtagtgc ctgaatttat agtagttcat gatggtttgc
    19921 cagaagattc atcagctcca aactattgga ttccatttaa agagtacatt aaaaacatag
    19981 cgtcatctga aatatattca acttggcctg aacagacaat ctatgcaaat gtaatagcta
    20041 taatatcatt tactttaaat agagtcttta ctgaatggta tagaaataaa ggatataact
    20101 ttacaataac ttcaacaaca gcatacgacc ataagtttat aaataataga aacttatttg
    20161 aaccaattaa cgtagttgta gatgctattt ttaatacttt tataaaaaga cctcctacat
    20221 caagacagcc actattagca caatattgtg atggacaaaa atcccaatgt cctgaccaaa
    20281 tgactcaatg gggcagtaaa gacttaggtg accaaggata tgactatgag agtatactaa
    20341 gatatttcta tggagatgag atagtatttg aaagagcacc tatagtaagt ggtgtaccag
    20401 tgtcattccc tggtactaca ctacaagttg gttcttctgg gcagtatgtt agaaccatac
    20461 aaaatcagtt aaatgctata tctaattctt atccagctgt accaaaagtt atagaggatg
    20521 gtatctatgg aacagataca gaaaacgctg ttaagatatt ccaaggaatc tttggtttac
    20581 ctcaaagcgg agtagtagat tttaaaacat ggtatgaaat atccagagtt tatgtagcta
    20641 caactagaat agcttcttta aatcctttaa tttaaagctt gatttagaac ataaactcaa
    20701 attattgaat aaaattatta atttaaaata aaagtggctg ttatgaacta atatatacca
    20761 taagtattac ttataagtat tgtagtctta acagccattt tttagttata acttgttttt
    20821 ttagaatctt aaaactttaa atgggggatt ttaagcttct taaaaacagt gcttagcaac
    20881 ttagatttct ttaaaatatt atatttattt ttaagtttaa taaaatgcta ttctaacgaa
    20941 aaacctactt tttatttaaa atctcactta ttatttaaaa cactatccat cacttagaat
    21001 attacttctt atataaatta ttatttatta taaatacaaa taatattaat ttaaaaagtt
    21061 attcctaatt taaataatac tactatcttc atcagtgaac ctaaactgca actttagact
    21121 tattagctaa agccaatatt agacctaaag ctatagatgc aaatgcagaa gcaattactc
    21181 tatactcagc agggaataaa aatacaattg tatgacatgg tatccagaaa aatggtatag
    21241 tttttaaaac actaaaacca aggtaagcat tccagtccac aatatttacc acatctttaa
    21301 gttttacctt aatccccttt ccaacctcat attttttatc tataaaacag tccataacct
    21361 tatggaataa aaatacagtt ggtgacatta gtatattcat agttgcactc ttaaatagag
    21421 catttgcaaa agctattccc tcaaatggaa gcataccatc cacttgtgct tgacctacac
    21481 ctgatgagta gattgacatt ccatatgtgg taactacacc tattattccc caaactattg
    21541 ctctataaaa tactcctact ggtattttcc aatccttata caaaattcta acaccaagta
    21601 aatctcccat tgtagctaat acagcaaact ttaaaaaacc tccaatatat ggatgtgcac
    21661 ctgttgcttc cataaatact tctctactac ttggtattgc taagacagca ataatacaaa
    21721 taagaactcc actccatata aaatcgcctt ttttcatatt tataaatact atttaatata
    21781 taaatagttc tcctttctat taaagattta tttaatttac aatctatcta caattattta
    21841 ttaatcactt attattagat attcattttc catatttaaa tttattctat ccctttatct
    21901 atttattttc ttactactct atccaccatt atctatatat ttattttacg attactcttt
    21961 caccctaacc ctttaactat ctattttttc ttactattct tatccacatc atccatatat
    22021 ttattttacg attactcttt cactctaacc ctttaactat ctattttttc tgatattctt
    22081 atccaccatc atccatatat ttattttacg attactcttt caccctaacc ctttaactat
    22141 ctattttttt ctggtattct tatctactat tatctgtata tttattttat gattactctt
    22201 ttaacctacc ccctatactt tatagtaata tgtttttaac ctttttcatt attcccaata
    22261 tgctttataa ctacaaatac tctcccccct taaaaataat aataaaatta atcaataaat
    22321 ttataatcat attattactc tatgtattaa gcaattacta tgccaataaa ctttgatttt
    22381 tttaaacaaa tcttaaaaat cctaaaatgc taattttctt taacttttaa tgaatctaat
    22441 agataacatt taattttcgt tatatttttc agaatatttc tattattatt tttaagaaaa
    22501 aaaaataatg ttaacatttc ttaacataca ttaaaaaatg ttaacattat aaattgggtt
    22561 taatactttt actttgactc gatttacttt tattctactt cttactttat ttttaactta
    22621 gactttattt ttttattact tatttgagtc ttatttattt tattctcact ccatatgttc
    22681 aattacattt gtctaaattc tttgatactt ttattacata attttaacaa gcttaagtgt
    22741 tatttgggta gtgcagttga taattattta aataatcatc aactgcatgt ttatatcatt
    22801 acagtagctt aatgtattta atcatactta cttaggattt tgaaatatct tagagattat
    22861 atttaacatt agtcaattgc tgcataattg taagcaattg aaatttgaga cccatcttca
    22921 ttttctatag tgataggctt cataattttt aatccttcag tttttatctt ttctaattct
    22981 tgttccattt tcttaattgt ttcctcaagg tctttttgac ttacatcttt gactgcatta
    23041 gggtctttag catagtcttt taattcttga atatgtttag catactcttc ataagtataa
    23101 tgctcaacac catacttttc caattcagta gggtcagtta ttcctgattt tattagagat
    23161 tcaaatttag gtaaagcaat attagatgaa tcatttccat ttgcaaatac tgctccagtt
    23221 cctcctagta ccattgcaga taccatcatt gcacttataa gggatttttt tattttcata
    23281 accaatcttc ctttcttaga gatttatttg ggtagtgtag tttaaaatga ctattgcaat
    23341 agttatcaac tacactctta gactatcaca gtagtcatgt ttatgtcaag cctttttaaa
    23401 aaacttttca ataaaaaata ctatctcaaa gcaaaattaa ttattttgag atagtatttt
    23461 aattctaaat cttttatatt actaagattt atggttattc tatccatgtt ctatattgtt
    23521 ctttattaac tgctaacaaa ttcccttttc ttaatatgac aaagcgatta tcattatagc
    23581 cacttcgctc aattgaaact tctcctgaat cagtataaag tacatcctta ctattactag
    23641 atttatttac atacgtttct tcactattct cagaattagt tactttgctc atagatgatt
    23701 cttcatgctc tctaaattca attacagata cttttgccgt actaaaatga gtctctccat
    23761 cacttttagc tttactaaca agaatatcag attctacttt gggagaatat aaatcagttg
    23821 atttactact tattgaaaat ccaattttat cactttgttc attttttgtt aaaccaaaag
    23881 attcaacctc attaatctct ttattttctg ttgcaaaaac aagacctgtc ccacaaacta
    23941 atacagttga aactaaaaaa gtaacataag ttgatttttt aaatttcata atattaacta
    24001 ttctcttttc tatttttgtc tttccaaatc cactacatat tgtcattgaa aatggattat
    24061 tctcctctgc tagacttatt agtgtggttg cataatcagc cctatattct tcaccaagta
    24121 tactcataac cttttcatca caactaaatt ctatgtcttt atttagtaaa aaaaacatca
    24181 cccaaactaa gggattaaac caatggacaa caagagctac aagcataaat aactttaaca
    24241 gattatcaaa gctattaata tgaaccattt catgagttaa aacaaagtct aaagtttgat
    24301 tattagcata attcatttgc tttggcaaaa taattcgtgg ttttaaaata ccagatgtaa
    24361 gtggtgtcct agtaaattca gatatgcaaa caataaatct tctaaaacgg ctattcttac
    24421 acatccattt tttaatgaac tcatgatttt ttatatgaat tgaagtttta aaaagattaa
    24481 ttattttaaa atatctaaag cataaaagta tgctaaacat aatagtaact ataaaagaca
    24541 aaatgcccaa catttccaac atcataatat tttcaatatt agacattatt tcaaattcgt
    24601 cagaattgtt tttacctgta gagtcactag ctttcttaag agtataattt tctgttgatg
    24661 tattacccaa ttccacatca aaagtcgatt caattatact ataaatacta aaaccagaat
    24721 ttaaacttac tggtattaga agtttaaata aaacaatcaa ccacaataat acaaatacct
    24781 ttttaggtaa ttttttaaat aaacatgctc ttataaaaat aactattaaa agtaatactc
    24841 cagaagtaaa actcatttct aacaatttaa tgaacataaa tcttacctca ctttaatttt
    24901 tcaacaattt gtttaagttt tgtaatctca tcacttgaaa gattttcttt attaataaaa
    24961 gctgaaagaa atttttctga agaccctcca aacattttat taattaaagt ttctgtttcc
    25021 tgtttttgta cttcctcttt gcttattaaa gctttacaaa caaaattcgg ctcaattctc
    25081 tctattgcac cttttgacac taattttttt ataacggtat acgtagtgtt tctattccat
    25141 cctgtttctt cttttaaaat ttttactaac tctccagcct tgctttctcc tctctcccat
    25201 agaacttcca ttactttaag ttctgaatca aataatttta tctccatata aaatcgctcc
    25261 tcaaatatag ttatcacaat agtcattact ataataaaaa actatcatag tagtctatac
    25321 tatgtcaatc atttattttt taataataaa aactgtcttt ttaaaaaatt cttataaaag
    25381 acagttttat caatgttata ctttaatgtt taattaaagc catattttat ttaaatatat
    25441 aactatctat cttagtacat agtataagat ttttctttat ctaatagtat atcctctaca
    25501 tctgggtttt cttttactaa ttgtctataa aaattacaat tagtaacacc cacatatgga
    25561 attagccata gtagacctat tccaagagta gctattgaaa gtatatacca tcctataaag
    25621 ctaaagttta gtacaaataa tttaagtaca tttcctttca tcatatctaa actagcaccc
    25681 attgatttaa atacacccat attatccttg tcttcacaaa ttaagaaagt agcttgagaa
    25741 acatataata gcaatatata aactggtaac ataagaacaa gtattataag aactagagtt
    25801 attccagtag aaataatagt ccctattcca acattatcac ttgataaata ttcaattgct
    25861 ccactagtaa gtaaaactcc aaatgataaa aacgctccta taattgtgat tataaaagaa
    25921 taaatataca caataattga ttcaaataaa taaaaaccaa aacttcttaa ataaattctc
    25981 ccacttacaa agatatctcc tatcttgact ttttcatctt tagtaatttt caagaacata
    26041 catgtaaatc ctgctgaaac gcaaaaagct attacagcca ctacaatagt agtcaatggt
    26101 tcaaaaggta atcctacaat tgatattaat actatcaatg caatatatac tgccatagaa
    26161 attgcacata tcccccagtt tccagataac tgagctttag atactcgttt taattcttgc
    26221 cttgatacca taaaaaacac ccctttcatt ttataaaaaa acttttaaaa atataaataa
    26281 tcttttaacg tataatatta atatatcata ttttcgacta tataagatac aattattcac
    26341 catgttttat caagatatgc cataattgta ttactagttt tatatagtca acattaccaa
    26401 atacatcaaa taaatttgat taattattca acaagtaata aaataatttc tattaatt
//
LOCUS       DAEPXW010000052        26124 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.053, whole genome shotgun sequence.
ACCESSION   DAEPXW010000052 DAEPXW010000000
VERSION     DAEPXW010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26124
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.053"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            61..798
                     /gene="cas6"
                     /locus_tag="KRM55_002192"
     CDS             61..798
                     /gene="cas6"
                     /locus_tag="KRM55_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH1594432.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKEREFYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            803..2278
                     /locus_tag="KRM55_002193"
     CDS             803..2278
                     /locus_tag="KRM55_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594433.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFCELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDIVIKSN
                     IEIDEIDKLDLKQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRIDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     MNTRNLGKKMINNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGREEYKMKNYIESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            2298..3314
                     /gene="cas7i"
                     /locus_tag="KRM55_002194"
     CDS             2298..3314
                     /gene="cas7i"
                     /locus_tag="KRM55_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBH1594434.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYRDKVHA
                     KTSIATITYDLRRILHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKEKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEREENEVLR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEEDGKLLLPEERKFMSKELREK
                     AVKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGV
                     IETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMW
                     YLKE"
     gene            3330..4127
                     /gene="cas5"
                     /locus_tag="KRM55_002195"
     CDS             3330..4127
                     /gene="cas5"
                     /locus_tag="KRM55_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBH1594435.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            4154..6562
                     /locus_tag="KRM55_002196"
     CDS             4154..6562
                     /locus_tag="KRM55_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH1594436.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            7003..7950
                     /gene="prmA"
                     /locus_tag="KRM55_002197"
     CDS             7003..7950
                     /gene="prmA"
                     /locus_tag="KRM55_002197"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBH1594437.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            7969..8727
                     /locus_tag="KRM55_002198"
     CDS             7969..8727
                     /locus_tag="KRM55_002198"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBH1594438.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            8729..10027
                     /gene="mtaB"
                     /locus_tag="KRM55_002199"
     CDS             8729..10027
                     /gene="mtaB"
                     /locus_tag="KRM55_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBH1594439.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            10070..10420
                     /locus_tag="KRM55_002200"
     CDS             10070..10420
                     /locus_tag="KRM55_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBH1594440.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            10583..10762
                     /locus_tag="KRM55_002201"
     CDS             10583..10762
                     /locus_tag="KRM55_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBH1594441.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            10792..11235
                     /locus_tag="KRM55_002202"
     CDS             10792..11235
                     /locus_tag="KRM55_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBH1594442.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            11346..11843
                     /locus_tag="KRM55_002203"
     CDS             11346..11843
                     /locus_tag="KRM55_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBH1594443.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            12036..12599
                     /gene="raiA"
                     /locus_tag="KRM55_002204"
     CDS             12036..12599
                     /gene="raiA"
                     /locus_tag="KRM55_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH1594444.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFVDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            12812..13048
                     /locus_tag="KRM55_002205"
     CDS             12812..13048
                     /locus_tag="KRM55_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBH1594445.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            13061..14404
                     /gene="yqfD"
                     /locus_tag="KRM55_002206"
     CDS             13061..14404
                     /gene="yqfD"
                     /locus_tag="KRM55_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBH1594446.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKDFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            14343..15458
                     /locus_tag="KRM55_002207"
     CDS             14343..15458
                     /locus_tag="KRM55_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBH1594447.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            15515..15976
                     /gene="ybeY"
                     /locus_tag="KRM55_002208"
     CDS             15515..15976
                     /gene="ybeY"
                     /locus_tag="KRM55_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBH1594448.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            15982..16701
                     /locus_tag="KRM55_002209"
     CDS             15982..16701
                     /locus_tag="KRM55_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBH1594449.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            16820..17221
                     /locus_tag="KRM55_002210"
     CDS             16820..17221
                     /locus_tag="KRM55_002210"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBH1594450.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            17285..18178
                     /gene="era"
                     /locus_tag="KRM55_002211"
     CDS             17285..18178
                     /gene="era"
                     /locus_tag="KRM55_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBH1594451.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            18190..19569
                     /gene="mgtE"
                     /locus_tag="KRM55_002212"
     CDS             18190..19569
                     /gene="mgtE"
                     /locus_tag="KRM55_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBH1594452.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            19642..19797
                     /locus_tag="KRM55_002213"
     CDS             19642..19797
                     /locus_tag="KRM55_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBH1594453.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            19763..20536
                     /gene="recO"
                     /locus_tag="KRM55_002214"
     CDS             19763..20536
                     /gene="recO"
                     /locus_tag="KRM55_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBH1594454.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            20529..21128
                     /locus_tag="KRM55_002215"
     CDS             20529..21128
                     /locus_tag="KRM55_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBH1594455.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            21288..22166
                     /gene="glyQ"
                     /locus_tag="KRM55_002216"
     CDS             21288..22166
                     /gene="glyQ"
                     /locus_tag="KRM55_002216"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBH1594456.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            22166..24232
                     /locus_tag="KRM55_002217"
     CDS             22166..24232
                     /locus_tag="KRM55_002217"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBH1594457.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVTLLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(24398..25945)
                     /locus_tag="KRM55_002218"
     CDS             complement(24398..25945)
                     /locus_tag="KRM55_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBH1594458.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEKLFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     IENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNKEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
BASE COUNT        10676 a         2569 c         4716 g         8163 t
ORIGIN      
        1 taatttttta tattacaaat agagaataat gaattatact agaaagtagg aggtgaaaat
       61 atgagcagaa tttcaatttt tatggaatca tgtaatggca aatttccaaa tgaaaattca
      121 atgttgtcag tttcctttat aaaaaatatt ttaaatgcag aaaacaaaga ttttgctaaa
      181 aacatattta actatgggga agaaagaaaa aacaataagc aaataaagga tataaataca
      241 gccatttaca taccaaatct tataagaagc aaaaatgagt tacttgttga tggagatata
      301 atattcaata taagttttta taattattct atgttcagta aattatacaa tggaatttta
      361 aaagtaaagg agctagaata taaaggttat agatttaaaa taaaaaatat aaaaatacat
      421 aaagaacacg agataaaaga aaatggtgtt atatttaaaa ctatgtctcc tataatagta
      481 aagaataaag aaggtaaata tttagatgta gaagattcaa attatataga atgtttaaac
      541 tatatagcta atctaactct ggagagtata agaggtagtg ggcttagaaa gccattggaa
      601 tttatacctc ttaacttcaa aaaaagagtg ttaaaagaaa agattcgtgg atttaaagag
      661 agagaatttt actatataaa tgcttatgca ggaacatttt ttttaaaagg aaatatggaa
      721 gatttaaatg cactgtataa aatgggaatt ggatatagaa ggacggaaaa tgcaggaatg
      781 gttgatatat taaagtagcg aggtgagaga aataaaagct aaattttata gatcaggtga
      841 tattgtaaga gatattggca ttgtttactt ttgtgaatta ctaatggatt taaaaaacga
      901 actagaaaaa aatgattata agctaaaatt tacttgtgag ttgaatagaa attatttatc
      961 tttagaatct gcagaatata tagaccctaa gtatatatct gattatatat tagaaaatca
     1021 actttttaag gtatttaaaa atgggaaaaa ggaaacctta gaaaaaatat ttagtaatat
     1081 agataattta acatatgtaa attttattga agaattggat aaatcttctg caactgagaa
     1141 acaaaaggaa gggattaaaa aagattttaa aaacagaaga tttccatatg ttagaaatag
     1201 tggtaagtat ggattaaaca cgagtctaga aaatatggaa acaaatgtaa aaagaatagt
     1261 cgatattgtg attaaatcaa atatagagat agatgaaata gataaacttg atttgaaaca
     1321 atatgaagaa aaagatagtg tatgtaatgt ttgcaatata aataaaacaa caaaactaga
     1381 tattgattta agagaacgaa aggactctaa gtataacttt ttatttagag gtgcagaaaa
     1441 atcaggtttt aaaagaagtg gacaagttga aagtaatatt tgttttgagt gtgaattttt
     1501 caacttaatg tgtcttttat atataaattt aaaaagacca atggtttttg catatacgaa
     1561 tgatttaaga gaattagcat ttttaaatca taagataatg cttaaaagaa aaatgtattc
     1621 agataaatca ttttataaaa aacttttgca tgaaaaaata agttcaatta gactatatag
     1681 gattgatatt gatacgaata aaggtataat tctaaaattt gactctatta tagagtataa
     1741 agaattatta aaaaaaattg aacttataga tattatagat aattataatt tttcaagaga
     1801 gccaatgaat actagaaatt tgggtaaaaa aatgattaat aatgggaatt tatcaaattt
     1861 aaaagaatta ttacttgata atataagtgt tttaaggcaa ctaactggaa cttctcgaga
     1921 aatggatttt gtatctagtt catataatat cggtttatat ataaaattgt gttggattgt
     1981 agatggaagg gaggagtata aaatgaaaaa ctatatagaa agtaatttaa tatattcaag
     2041 agtaggtaaa gacttattta ataaaatgac agatgaatcc agaagaaaaa atttttctat
     2101 gaaagtgatt caactactta agtctaatga tagaactcag ctatttcaaa ctataatgca
     2161 tgtgttagtt tctaatggaa tcttaatagg agaagggttt gtagaaggtc taatgcagag
     2221 ttctgaatta gaattaaata cgaatgtagg tctatttatt caagaaatca tgaaataaaa
     2281 aagggggaaa atttaaaatg aatgaaaaaa gagtaaaagg agtaacatta actatactga
     2341 cagaaagccc agttccactt tcgtatgacc aagggtatgg aaattataca ccaataaaaa
     2401 aagaacaata tagagataaa gtacatgcaa aaactagtat agctacaata acatatgatt
     2461 taagaagaat actccatcaa gaatatggtt ggaatttaag taatattgtt tttggaaaaa
     2521 aaggaaatat atatccatct attaagaaaa atgtaggatg tgtagatgaa aatggattag
     2581 agactgatgt atttggttat ttaataccac ttaaagagaa aggttctata agtaaggctt
     2641 ctccgcttag aataatacct tttaggtcat taaattcata tagaggttca acacagttga
     2701 taacaaatag aggtttttta agtagcgaat ttggtagaaa atattatgat gagagggaag
     2761 aaaatgaagt acttagagat gaaaactttc caacaacaca agcattagca atagaagaga
     2821 ctttatcaga ttactacgtt tatacaataa cattggagct tgatagaata ggagtagtag
     2881 aagtagaaga agatggaaag ttacttttac cagaagaaag aaaatttatg agtaaggagt
     2941 taagagaaaa agcagtaaaa gatatattag atgcaattac tgtgtttaca agaaacataa
     3001 aacattcatc agtactatta aaaccacttg cagtaatggg tggagctttt gataaagttg
     3061 taccattttt ttgggatgat gtagattata atgctgatag tggtgagata aatttagagg
     3121 gagtcataga aactatagaa agttatagcc ttaaagaaag taacacaata cttgctatca
     3181 atgacagatt aaaaatttct aataaaaagg aattaaataa gtttaattta agtaaatacc
     3241 ctgtaaaaga gattaaaaat ctagcagata gattggaaat tggagaagat aatatgtggt
     3301 atttaaaaga gtaggaggtt ttttgaatta tgaaagtatt acaatgtaaa cttaagcaac
     3361 caactgctca ctatagagac ccaaaagtat ttcaaaatga atatataagt actttaaatt
     3421 taccatctaa gaccacaata atgggaatga taacgtattt atgtgataga agattaaact
     3481 ctgatataga tataggaata attggaacac atcatcatag agaactagaa ttttcaagag
     3541 gagagaacat tgatttttgg aatgaatata caaatatgag aaaaggcaaa gataaagaaa
     3601 agtttttgct tcaaggaaac tactatgatt actataaaga acataaagct caaaatagca
     3661 tattaaacta tgaagttctt aaagaagtag aactgactat atttatttct tgcaaggatg
     3721 atgaagaact tgaatttatt agaaaaaagc ttgaaagtcc atgtaaatat gcaaatttag
     3781 gaagaaaaga agattttgta ataccaagtg aaaaagggtg ttttgtgaaa gaagttgagt
     3841 taaaagaggt tatacctatg aatactcgtg atgctataaa agaaaatata aaattaaaga
     3901 atacatatgt aagagttgac ttaagagata aagagaatgt cgagactata ataaatcaag
     3961 gtgtattgat tgcattacct tataaatata aagatttaga agcaaataga gatgatagag
     4021 tttatgagtt ttgccattat atatatgttg ataatgatgg tatatatcct aaaaatatta
     4081 aggtaaatgt atgtattgat acaaaagaag tttttacatg gctttaaatt attttgaaag
     4141 ataggtgttt atcatgaaaa atatcatgca aaaagaaata ttagctaagt catataattt
     4201 aagaactaat caacaagagc aaacattagt tgaacatatt aaggatttat ttgaagtatt
     4261 agaatctata ttagaactaa atctatattc agataaagat gtagagatac taaaaatatg
     4321 ttgtgctttg cacgatttag gaaaaattaa ttcaattatg caacaaaaaa tggagattaa
     4381 taataaaata tcgtatagtt gctcagaaga agagaggaaa aagttagagt ctgacaaaaa
     4441 atctttaaaa aagatagcaa gacataatat attttctgga gcatttttaa aagatatatt
     4501 agaaaaaatg aacttgtcag aagaagataa gttatatata tataaaagta taatgttaca
     4561 tcatggaaac tatgaagatt atatgaggtt aagtattagt aaagttcaag aagaaattta
     4621 tgagtatatt gaaaaaggca ttttagaaaa agaagagttt aatctgaaag atatagaaag
     4681 ttatataaat agcattttaa atgtagactt taaatttggt gaagatgtat tggattatga
     4741 ttacatagat aaattaagtg aaagtatgtt tatagacagt gattataaca atggtcaaat
     4801 agatgattca gttttaaatt atagaaagtt taagtatatt ttatataaag ggatgctgaa
     4861 cttaatagac catagtgcat caagtagaca gaaaggtata aaattttata acgattttac
     4921 tgatgaagaa attgataata tgattttaaa tgagatatat aagagtcagg gtaatttgga
     4981 aaaaaataat atagagttca atactataca aaaaaggttg agagaacttt ctggaagaaa
     5041 tgttctgact gttgcattta caggttcagg aaaaacagct gcagattata gaaagacttt
     5101 taaaagaaaa ttctttttag tgccaaataa aatatcagca gaaagttttt atagaaaaaa
     5161 tatttttcaa aataaaaatg atttagatac aagaagtagt aatgattaca ttggattact
     5221 tcatggagat ataaacttat attcagagaa tgaagataat ggagaacatg attttgtatt
     5281 gacattaagg gatatagatt tgagtataaa cttttgtaaa ccttgtgtaa ttgcaacagt
     5341 tgaccagtta ttacttagta tgtttaaatt tccgggatat gaaaaaatat tcgcagccgt
     5401 aaaaaatgca tctataactg ttgatgaagt acatttattg gaaccaaaga tgtttttgat
     5461 tttgatatat tttatgcagt ttgcatgcaa gtacttagat gttgattttc acttaatgac
     5521 agctacactt ccaaaatcat ataaagagca aatgataaac aagggaatta tttttcaaga
     5581 agaaagtaat gaaaatgtta ctgataaagg agaaatagtt tttattgaga gcaacaagga
     5641 agaagagatt tgtgaaggta aagatgtaaa ggtttctttt ataaaggaaa aagaaatcaa
     5701 gtcaatagtt gaagatgctt tagaaaataa acaaaaaatt cttataataa agaatactat
     5761 tgattcagtc aatagaacat atgagttttt aaaagaaaat ttatctgata agtatggtgg
     5821 tgtagatata gatgttttac atagtagatt taagttcaaa gataaaaaag agaaatatag
     5881 taaaatatta aatggagagg gtgatatttg gatatcaact caatcagtag aaatatcctt
     5941 ggatttggat ttcaatataa taataagtga tttagcaact atggatagct tgatacaaag
     6001 aatgggtaga tgtaatagaa ataataaata tgaatatgga aacttttata ttctacctag
     6061 tgaagataaa atttatgata acaaacttaa gaacacaact aaaaacatct taaaggacat
     6121 attaaaaact aactctattt ttacaatggg gattagaaaa actattttgg atgattacta
     6181 tgataatagt gtagttaaaa aatattttga agagaatttt ataagttgtg ataaagaaat
     6241 taagaatatt tatggtataa ataaagaaat ttttgatgga ttggatttaa tttttaattt
     6301 tgaaccttac aaaaatattg ttgatagtaa gaaggaagca gctaaaattt ttagagatgt
     6361 tgatgttagt tacaaaatta ttctggaaga agatttttat aaggaagata gggagttaca
     6421 acaagattcg attcaagtat cagggtttat atttaataga ttatattatt atggattaat
     6481 aagcaaagta gaaggataca tggtactaaa atctagtagt aagtttgagt ataatagtac
     6541 tgtaggctta attttgaagt gagcatatgt ttaaatataa tataccttta gacattgaaa
     6601 atacaaaaag tactactgta agtctactgt aaaaactatt ttttaaaagg aaaaataagt
     6661 tgtgagatag agtgtttaca agtgtatata gataataaat ttgaggctta agattaacta
     6721 agtgggtttc aggtacatcg cgaaaataat tataagttgg agattttgta tgtttaagat
     6781 taactaagtg gatttcaaat attgatatag tagatataat agaagtttta ttattaggtt
     6841 taaaattaac taatcggatt tttaaatatt ctgactatta tataaggata ttattagatt
     6901 gaatttaaaa ccaataatat aaaacaacaa aatattatat ttatgatata ataaaagtta
     6961 tggaaaaaca ggaatattac tatagagaag agaggtaaac ttatgaataa ttggatagaa
     7021 gtaactataa aaacaacaac agaagcagtt gaacctataa cgaatatact atatgaacaa
     7081 ggagctggag gagctgtaat agaagaccca aaagactttt tattccaaaa gaaaaatgaa
     7141 ctagactggg attatgttga agaagaagta tttaaaaaga atgaagaaga tgatgttctt
     7201 ataaaaactt atgtttctga agaaaaaaat gtgatggaat ttgtcgaaat aataaagcaa
     7261 aaagttttag gattaaaaga ttttggtata gatataggtg aaggaagtgt atcattggac
     7321 caagtaaatg aagctgattg ggcaaatgca tggaaagcat actacaaacc aacaaaagtg
     7381 ggacaaaggg tagtagtaaa acctacatgg gaagattatg ctatgcaaga gggggattta
     7441 atcatagagc ttgaccctgg aatggcattt ggtacaggga cacatgagac tactagtatg
     7501 tgcattagag aattagaaaa gtatgtgaat aaagattcta aagtatttga tattggatgt
     7561 ggtagtggaa tccttgcaat agcagcagcc aaattaggag caaaagaagt tgtagctgta
     7621 gatttagatg aagtggctgt aaaagttgca aaagaaaatg ttcttgaaaa taaagttgaa
     7681 aaaagtgtat ctgtaatgca tggtaattta accgatgtaa taaaagataa agcggatgta
     7741 atagttgcaa atataatagc tgatataata aagatacttg caaaagatgt tcaaaacttt
     7801 atgaaagaag atgctatatt catatcttca ggtataattt tggataaagt agaagaagtt
     7861 aaagaaagct taattgaaaa tggatttgaa atagttgaag ttcaaaaatt aggtgaatgg
     7921 tcagcaatag tttctaagct taaaaaataa gggatatggt gacgtataat ggatagattt
     7981 tttgttgaaa aaaataatat aaatctacaa gataaaactt gcactataga aggtgaagat
     8041 gtaaaacata tttcaaaagt tttaagatgc aaattaggtg agaaacttga aatatgtgac
     8101 aagaataata atgagtatat ttgtgagata atgaatatag ataagagtat agttaattta
     8161 gagattttag aaaaagttga tataaataga gaatcagaac ttaaagtaag gctataccag
     8221 ggacttccaa aagctccaaa aatggaaatg atacttcaaa aattaactga agtgggtgta
     8281 gaagaaataa tattagttca aactaagaga agtgttgtta aagttgatga caaaaaagaa
     8341 gataaaaaat ttgaacgttg ggaaagaata atttatgaag cagcaaagca aagcaaaaga
     8401 ggtaagatac caaaattaag aggtgtttta agttttaaag aagctttaga agatatgaaa
     8461 aaaaataatg taaatatttg cccttatgaa aatgaaagaa cagtttcaat aaaacatgca
     8521 ctaaaaaaat gtgattctaa tatagatagt gttggaattt ttataggtcc agaaggtgga
     8581 ttttctgaag aagaaataga acaaatacaa aaaaataatt gtaatgttgt atcattgggg
     8641 cctagaatat taagaactga gacagcttct gttgtagcat caacaatagc tttgtatgaa
     8701 ctaagtgatt taggaggaga aaaataaatt gaaaaaagta gctttttata cacttgggtg
     8761 taaagttaat caatatgaaa cagaagctat gctagaacta tttgagaaag atggttatga
     8821 acaagtcaat agtgaagagt atgctgatgt ttatgttata aatacatgta cagttactca
     8881 tatgagtgat agaaaatctc gtcaatatat aagacgagtt aaaaagaaga atccagatgc
     8941 aataatagcc gttgtaggat gttattctca ggtatctccg gaagaaattt tggatataga
     9001 agaagtaaat ttagtcatgg gtacaaatga tagaagaaag attgttgaag aaattaaaaa
     9061 gataaattca agtaagaaag ttagtacagt tgacgacata atgaaagtta aagcttttga
     9121 agaaatagaa atcagccaaa ctaatggaaa gactagagca tttatgaaaa tacaagatgg
     9181 atgtgacaga ttttgtactt attgtatcat tccttatgcc cgaggacgcg ttagaagtag
     9241 agatattgat agtatagtcg atgaagtgaa aaaattggct aataatggct ataaagaggt
     9301 tgtattaaca ggaatacatg ttgcctctta tggaaaagat ttaaaggata gggatattaa
     9361 acttcttgat gtaataaaac aaataaacca gatagaaaaa atagaaagaa ttaggcttag
     9421 ttctgttgaa ccaattttat ttacagatga atttgtaaat gaagttttaa agatggataa
     9481 agtttgtcct cattaccatt tatcacttca aagtggatgt gatgaaactc taaaaagaat
     9541 gaatagacga tacacaactt tagagtacaa aactattgta gatagattga gaagtaaaat
     9601 gccagatgtg gcaataacta cagatgtaat agtaggtttt cctggagaga caaatgaaga
     9661 gtttaaaaaa acgtacgagt ttttaaaaga aatagagctt tcacaaatgc atatttttaa
     9721 atattcacca agaaaaggaa ctccagctgc aactatggaa aatcaagttg accctcaaat
     9781 gaaacacttt agaagtgaac aacttttaaa tttaagtaaa gtaaatttta ataaatttgc
     9841 aactaaattt atcggccgtg agttggatgt tttgtttgaa caaaatatag aaggcaataa
     9901 atatgaggga ttaacttcaa attatataag agttgttgtt gaaagtgaca aaaatataca
     9961 aggtcagata ttaaaagtga aaataaatga tgtaaaagat gaatatgtag aaggaatttt
    10021 gctataacat gtagaaatta taatatttat aagataggag gtggaaagaa tggattgtat
    10081 tttttgtaaa atagcgaacg gagaaatacc ttcaactaaa gtttatgaag atgatagagt
    10141 cttagctttt aatgacttga acccagttgc tccatatcat atattagttg tacctaaaaa
    10201 acattatgat agtttaattg atattcctga taaagagatg gacattgtgt cacatattca
    10261 tgttgttatt aataaaatag ctaaagagaa aggttttgac caaactggat tcagagtcat
    10321 aaataattgt ggaagtgatg gagggcaaga agttaaacat ttgcactatc atattttagc
    10381 tggtaaaaag cttcctaatt acgaagcggg acaaaactaa actaaattat tgaaaaattg
    10441 agttccttct tgataaaaat acttgataaa agtaaaaatt tagtttataa taaacaaagt
    10501 gttaggttgt aatgcatatt atgcaaaaag aacatagtta cagtcccagc ataattgcgc
    10561 tattggaggg agggaaaaag aaatgtcaga agtaagagtt agagagaatg aaacattaga
    10621 cagcgcttta agaagattca agcgtcaatg tgcaatgtct ggcatcatgt cagaagtgag
    10681 aaaaagagag cactatgata agccaagcgt taagcgtaag aaaaaagctg aagcagcaag
    10741 aagaaaaaac gctaagaaat agtagtaaat aagaataaag aggtgaaggg gatgtccctt
    10801 aagcaaaagt tacaagagga tttgaaatct tcgatgaaaa acaaagatac agtgagaaaa
    10861 tctgtagtaa ctttaataag agcttctata aagcagtatg aggttgataa tagggtcgag
    10921 cttgatgaag atggaattat cgatgtaata gcaaaacaat taaagcaacg tagagatgca
    10981 ttagttgaat ttgaaaaagc tggaagagaa gacttaataa aagaaacaga aggtgaaatt
    11041 gaagttttaa aagagtacct acctcaacaa ttaagcgaag aagagttaga agaaattgta
    11101 aaatctacta tatctgaagt aggggcaact tctatgaagg atatgggaaa aataatgtca
    11161 gttatccaac caaaagttaa aggaagagct gacggaaaac ttataaataa gttggtaaaa
    11221 caaaacttac aatagattga tatagcctag agagaaatct ctaggctttt tatagttttt
    11281 gggaataacg agtcatattt gagcatatct ataatcaaag aaaattttga aagaagggga
    11341 aaaatttgat tatatcagta aaagagatta ggaatttttt gataaacata tttataccac
    11401 taataatagg ttacttaagt agcatcttaa caatgattat cagtggaaca gatatttcaa
    11461 cctattattt acaactcaca aagccaagct ttgcaccacc agcttttatc tttcctatag
    11521 tttggactat attgtacata ttgatgggta tatcttcata cctaatatta agaaaaggtt
    11581 acaacttacc taaagtaaga gatgcaattt tttattatgg attacaactt gtattaaact
    11641 ttatttggag tatactattt tttggatttg gacttagatt tacagctttg atagatataa
    11701 taataatgat tttggtttct ataataatga tttcgaagtt ttctaaaata gataagagat
    11761 ctggatacat aaatttgatt tatttaatgt ggcttgttta tgcaggattt ttgaactatt
    11821 ttatatggtt tattaataaa tagaatgtaa agattttgta aattaccctg tacttttaat
    11881 aatatcataa caaacgaaaa ataaatagac tattaaaaat aatcattttc atatacaata
    11941 atattaattt aaatacaata aatttataaa aattgtattt aaagattaac atattaaagt
    12001 attagaattg gaaaggcttg aagggagagg tttttatgca aataatagta tctgggagac
    12061 aaatgaaatt aactgacgga ataaaaggat acgtagatgg aaaattaagt aggttagaaa
    12121 aataccttga tcctgaatca gaagtgaaag taacagtaag tgcgaaaaag gatagacaaa
    12181 aagtggaggt tacaataatt cctattaacg gtcaaataat aagagcagaa gatgtagaag
    12241 atgacttata tgcagcaatt gatattgttt gtgacaaatt aagtagacaa gttgtcaaat
    12301 ataaaactaa agttaaagac aaagttcaaa ataataagag cataagattt gaaaatcttg
    12361 actttgtaga taatagcagt gaatttgatg attatgatta tgatgatgaa gaagatgaaa
    12421 atatagtaat agaaagaaga aagaaattta atgtaaaacc tatgagttct gaggaggcga
    12481 tacttcaaat ggaactagta ggacacaatt tctatatgtt tagaaaccaa gataattttg
    12541 aaataaacat agtgtataag cgtaaagctg gtggatatgg tttaatagaa caagattaat
    12601 aaaaattgta tacgtttaga ttttatataa gaaaaaataa aaaggtaatc atgttgattt
    12661 tttatcaata tgattacctt tttcttgttt aaataatata ttagatatta ggtatttatt
    12721 atataaaaat tttaaaacta atctgttaca acatcaataa agtgcataaa tacctatttc
    12781 aagcataaaa ttaattaagg gggtaatgct tatgttagaa atatccactg atttacaagt
    12841 aaatcaacca gttattactg ttacaagtaa tacgtttatt agtatagaaa attatctatc
    12901 aatattagaa tatgaagttg atttaataag aataaagact aaagttaaaa caattaaaat
    12961 atctggggat aaactttcac ttaagtatat tactgatagt gagataggta taaaagggat
    13021 tatctacaat gttgagtatg ttgattagga ggagatacac ttgataagtt ttataagggg
    13081 atactatgtt atagttgtgg aaggagtagg actcgaacaa tttttaaatc atcttataag
    13141 aaatgggata agtgtttaca atgtaactag aataaaaaat actaaaatgg agtttcatat
    13201 agatagacaa gatataaaag actttaagaa tgtttataga ggaagtaagt ttgatataaa
    13261 ggtaaagcaa aaaactgggg tcccttttat tatcaaaaga gtttataagc acaaaggtat
    13321 gtggatttgt gctcttgttt ctttattttt attgatgtct acatcgcagt ttgtgacaga
    13381 tgtatatata caatctcctg aaggtataaa aaaagaagct cttagaaatg agctttataa
    13441 ggttggagta aggccaggag tctataagaa gagtattgat agaaaagaag ttagagacca
    13501 tatgatgtca aaatttaatg atgtggcata tttatctatc aatgtaaaag gaacaaatat
    13561 atttgttact gttacaaaaa aggcagaatc cctaaaatct acagaccaat caaattattg
    13621 taatgtaatt gctttaaaaa atggtataat agaaaaggta atccctagaa gtggtaaatc
    13681 agttattaaa tctggagaca tagtccaaaa gggagatgtc ttattaaatg gagctaatac
    13741 caagtcaata ccagaagtat gggcaagtac tttttatgag tccacaaaaa aggcaagtta
    13801 tgtagatact gtaaataaaa aaactggaga aaagaaaaat atatatacac taagttttta
    13861 tgataaagag tttacaatga gaaaaaatat aaaatataaa gattatgttg ttgaaaataa
    13921 agaaaaaaaa ctatcaatag gaaactatac ttttccaata aagataaaaa cgagtacttt
    13981 ttatgaaaca aaaaaggttg aagtaaaaag gaataaagaa gagttaaaaa aagaattatc
    14041 tgaaaaagct ttaaaagagt tagaatacat aatcccagct tcggctagaa taatagatgt
    14101 aaaacataac tttaaggtta ataaaaatat gttagaatat ttaataacag ttcaaactag
    14161 tgaaaatatt gctaaaattt atcctcttag taagtcagaa gcagaaaggt ttataaagga
    14221 agaaagtaaa ccagatgaag gtgaagagga agttccttcc aatccagaaa aaagaccatt
    14281 aaatgatata agaaatgagt ttgatgagga taataaggat aataaagacc aaaacaattc
    14341 tgatgaaaat aatagtaatc aaaatagtaa taatagtcaa aataataata gcaataacaa
    14401 ctaataaaat taaacttaaa atcttaggag gactaattca attgataata caaaagaaat
    14461 ttacaatagc agatggtaac tttgaaagag agttatttgg caactttgat gaaaatgtaa
    14521 aattaataga gaagacttta aatatagatg taatacttag agaaggcaat ataattttaa
    14581 ttggagaaga aaaaaatgta gattctgcat taaaacttat gaatgaatta caccaaactg
    14641 tatcaaatgg taagcattta gataagcaga gtatttctta ttcattatct cttttgcttg
    14701 aaggaagtga acaaaaaata aaagaacttg aggggacaat cgtcataact caaaggggaa
    14761 aagctgttca acctaaaact ttaggtcaaa aagaatatat aaaacttata gaaaataatg
    14821 atataacttt tggtgttgga cctgctggaa caggaaagac ttatcttgcg gttgctatgg
    14881 cagtaaaagc ttttaaaaga gatgaagtta gtagaattat acttacaaga ccagctgtgg
    14941 aagcaggaga gagtctaggt tttttaccag gagatttaaa ggacaaagtt gacccatatt
    15001 taagaccact atatgatgcc ttatttgaaa tgttgggtgc tgataaattt aataagtatt
    15061 tagaaagagg tactattgag gttgcaccac ttgcatttat gagaggtaga acacttgata
    15121 attcatttat aatattggat gaagctcaaa atactacttc tgaacaaatg aaaatgtttt
    15181 taactagact tggatttggc tctaaagctg tagttacagg agatgtaact caaacagatt
    15241 taccacaaaa taagaagagt ggtctaatac aagctacaga gattcttaaa ggtgttccag
    15301 gtattgggtc tataatgcta acagatagag atgttgtaag acatgagttg gtacagagaa
    15361 taataagagc ttatgagaag cacgacaaaa gagaagaatt taaaaaagaa gaacgtaaaa
    15421 aagcgaaaat gcaggaaaag actttcaaaa gaaagtaaaa gtgtagtaat atagatatat
    15481 agcattatta atgaataaaa agtaggtgta gtgaatggat ttgatactag atgatagaca
    15541 agataaatta gaagtaagtg aggagttaat tgaaaagata aaggatataa tcatagaatg
    15601 tttagattat gaaggatatg atgataatta tgaagtgagt ctttcttttg tagataataa
    15661 agagattcat gaattaaata gagaatatag aggagttgat agagtgactg atgttttatc
    15721 atttcctctt ttaagtgatg attttgagga tgttgagtta gaagaagaat ccctaggtga
    15781 catagtagta tctcttgaaa gagccttaga acagagtata gagtataacc atagttttga
    15841 aagagaagta tgttttttaa tatgtcatag tatgtttcat cttttaggtt atgaccacga
    15901 tacagatgaa aatacaaaag aaatgagaga aaaagaagaa cacatattaa ataagttaaa
    15961 cataacaagg gagtagtttt tatgaaacca gaaaaaactc gtcaaggtat aattaaagca
    16021 tttaatgcag ctatagaagg gatattgtat acatttaaat ttgaaagaaa tatgaaaata
    16081 cattatttag gttcagttgc tgttcttata ataagtttgt tttttaactt ttcaaaatta
    16141 gaaatgataa tgttacttat gtccatatgt ttagttgtag ttgctgaaat gtttaataca
    16201 gctatagaaa aagctgttga tttagtaact gatgaatatc atgttcttgc taagatagca
    16261 aaagatgttg cagctggagg cgttctagtg gcagcactaa attcagtagt agttggatat
    16321 attttgtttt atgataagtt gacagatata tctggaatat taatttataa aataagagaa
    16381 tcagaattac atataacctt gatatgtata ttattggttc ttatagctgt tgtagttgta
    16441 aaagcattga cttctacagg tactcctcta aaaggaggaa tgccaagtgg tcatgctgcc
    16501 ttagcatttg ctatagcaac tgcaattaca cttatgactg aaagagtagt tgcctctact
    16561 cttgcatata taatggctgt attagttgcc caaagtagaa ttgaaggaaa aatacatacc
    16621 ttttgggaga ctattgctgg agctttgtta ggtgtgttga tagctatatt agtatttcag
    16681 cttggaatgt tctataatta aaataaatgt acataaaata tttaaaataa aacaaatctg
    16741 tgctaattaa atttttatga tataatgtag agtattaaat aaaaataact tttaattatt
    16801 gtatacagga ggagttgttg tggataacat agaattgtta aggttggcag aagatgccag
    16861 acaacattct tatgctcctt actcaggttt tagagtaggt gcagctcttt taactaagag
    16921 tggtaaagtt tatactggat gtaatataga atgtgcatca ttaggtggaa caaattgtgc
    16981 agaaagaaca gctattttta aagcaatatc agagggtgat aaggatatct ataaaatagc
    17041 tatagcaagt gataactcag aaaataatga gcaaacatat ccatgtggaa tatgcaggca
    17101 ggtaattata gagtttggtt ctgatataaa aataataacg ggatatacta aaggagaggt
    17161 gtttgagcat agtataaagg atttgttgcc aaactatttc tctggaaatg atttaaaata
    17221 aatttaaaag tataaataaa tttaagtaat taaaacaaga agataaaaag ttaggagaca
    17281 gttaatgttc aaatcaggtt ttgtcagtat agtgggtaga ccaaatgtag gaaaatctac
    17341 tttaatgaat aatgtagttg gagaaaaaat agctataatg agtgataagc ctcaaactac
    17401 aagaaataca atacaagcag tatatacaga tgaagaaatg cagatagtat tcttagatac
    17461 accaggtatt cacaaaccaa aaaataaatt aggtgaattt atggtaaagg cagcaacaga
    17521 agcttttaaa aatgtagatt taatattatt tgtagttgat gattctaaaa aaataggtcc
    17581 tggagataga aagataatag aggatttaag aagtgttaag acaccaataa ttttagttgt
    17641 aaacaaaata gaccaactag accaaaaaga tgagctattt gatataatca aaatgtatga
    17701 tagagaaggc atttttaaag aaatagtacc aatatcagca ttaaaaggaa agaatacgga
    17761 taccttaata aaagttatac aaaattattt agaagaaggg ccaaagtatt ttccagatta
    17821 tatgattaca gaccagccag aaagagtatt aatagcagaa cttataagag aaaaagttct
    17881 tcactatctt aatgatgaaa tacctcatgg tgtagctgtt gaaattgaaa aaatgaaagc
    17941 gagaaatgat aaggaaatag tagatgtatc tgctgtaata tactgtgaaa gagattcaca
    18001 taagggaata ataataggaa aaaatggtag gaaactaaaa ggaataggta agtcagcaag
    18061 acaagatata gaattgcttt taggttcaca aataaatctt caattatggg ttaaagtcaa
    18121 agaaaattgg agaaatttac aaaattatat aaataatttt ggatataatg ataaataaag
    18181 gtgggttata tggataggaa actggatgct tcccaagatt tattatatga agtaaaatca
    18241 ttaattgata ataataaagt attggagtta agagaattaa tagaggaata tcatataatt
    18301 gatatattcg atataatgga aaatttagag gaagacatga aaattcaatt atttgaagta
    18361 cttcctttag atatggcatc ttctatatta gaagaaggta gtgtagagtt ttttattagt
    18421 attttatcta aactggatgt agaacactcg aaaaatatac ttgaacttat gtctcttgga
    18481 gatatggcag acaagttgag tgaacttgaa gaagaagaaa gagaacacat aataaatctt
    18541 ttgaatcaag agaatgccga ttatgtaaaa gagttactat tctatgatga agattctgct
    18601 ggtggaacaa tgaccactgg atatatttct ataaataaag atatgacagc tcttgaggct
    18661 atagaccata tgagagaaga agctgaagaa gctgaaacta tttattatat atatgtggtt
    18721 gatgatgaag aaaaactagt tggagtattg tcattaagag aattaataat agctagagac
    18781 gcaaatatag tagaagattt gatgagtgaa aatataatct ctgtttatgt agatgaagat
    18841 agagaagaag cagtaagatt agtatctaaa tacaatttaa tagcaattcc agtagtagac
    18901 agacaagaaa aattaaaagg aataataaca gtagatgata taattgatgt aatggaagaa
    18961 gaagcaactg aagatatgta taaatttgca ggaagttcag aacatgaaag agaagttgct
    19021 gaaaaagaaa accctacatt gagagagcaa ataatatcag cacttagagg acgattacct
    19081 tggttaatta ttaccttagt tggagggttg ttggcttcgt taatactttc taacttagac
    19141 tatataatga atcctgtata tgctccatta gtatttttta tacctgtagt aattggtatg
    19201 ggtggaaata ttggaactca atcatcatct gttacagtaa taacattatc taataaggat
    19261 ttaaatttta gcaatgtggt tagagaaggt attgtaggta ttattacagg tcttttgtgt
    19321 agtataataa caggtattgt aatttacttt gttatgagaa agttagacat tgtattaatt
    19381 gtttcaatat cattatttat aaatatggtt ttaggtgcaa caataggtgc gtttatgcct
    19441 gtcttattaa aaaaaatgga tgcagaccca tctacagttt catcaccaat tatatctaca
    19501 gctcttgata taactggtat agcagtttac tttataataa caacggcatt attgtcaaaa
    19561 attgtttaat aactttatgt atgatttatc ctcttcttac taaaaatata agtataaatg
    19621 taagaagggg gttttttaaa aatgaacaat atcagttggg aagtttttaa aaaaacaggt
    19681 agtatagatg catatttata tttctgtgat tgcaaaaaca tacatgaaga aattgaagaa
    19741 gtaagggaga aaaaagaaga cgatgataat cctgaacacc caggggatag tacttaaagc
    19801 tataaggtat aaggaaagtg acataatact tacactattt acaagaaagc ttggaaaagt
    19861 atctgcaata gcaaaaggag ctaaaaaaaa taagagctct ttgctttcat catcacagtt
    19921 attttcttat agcaatttta ccttaaaaaa acaaggtaat atgtacaagg ttactcaaag
    19981 tgaaataata aaaagttttt ataatatatc ctatgatata gaggcatttt cttatgctac
    20041 atatattaca aaattagttg aaaattctat acttgaaaat cagactaata ataggctatt
    20101 tatattactt gcgcagactc tgtatttgta tacacaggat aatacagaca ataggtttat
    20161 aacagcagca ttcgagttaa aatttttaga ctatatagga tttaaaccta tagtaaataa
    20221 atgcattaat tgtgaatgta aaattttaca aaattctgtg tttaatatct acgaaggtgg
    20281 tatactatgt agtaagtgta gtaaactttt tgataataat ataaaattag acttaacaac
    20341 tataagtctt atggaatatg tattaagaaa tgatatttta acatgtagta aagctaaagt
    20401 atcaaaatat ataacacatg aacttgagaa tattctagac aagtatttga aagtttatgt
    20461 tgataatatt aattttaaat cattacacgt attgcaaagt gtaaaaaata ataagggagt
    20521 ggataatgat gagtagtaat ataactattg aaatggttga ttcagtcttt gaaagagttc
    20581 caggagcaac ttatgcagaa gcaaaagaag cattagtaat gtgcaatgga gatgtaattg
    20641 aggcagtaat atatttagaa aataaaaaaa atacttgtaa ttgtaaagca aaatctgcta
    20701 aagaaactat ggaagaagta tttggcaaag atggagaaaa tataaagttt caattaaaag
    20761 agcttcttag aaaaagtagt gtagtaagaa taatagttga aaaagatgga aaaactatga
    20821 tgaacattcc tttaacagtt ggagttgttg gattagcttt tgtaccatta gctactttag
    20881 ttggattatc agctgctgtt ataagtaaat atcgtataaa agttcaaaat gaagaagatg
    20941 gagaaattgt agatttaggt gaattgaatg aagaaaaact tcacgttttg aagaatatga
    21001 taactaatgc agcaaaagat gtgaaggatg tagtagttga caaaaaagaa gatgacaaag
    21061 atgtaactgc tgaccttatg aaagaagaat ctgaaaagaa taaagaagac gaagacgaaa
    21121 ataaatagat ataaagtgac ttttaaaaaa tgaagagaag ataattataa gaattatcac
    21181 taacattgac aaattttata gaatttgata ttctaaaagt tgtagaagaa ctattaaaat
    21241 agcctttcgt gtagacgaga ggctttattg ttataggagg gatttttatg aattttcaag
    21301 agatgatact ggcgttgcaa aaatactggt caaagcaagg ttgtatcatg atgcaacctt
    21361 atgatattga aaaaggtgca ggaactatga atcctaatac ttttttaaga tcattaggac
    21421 ctgagccttg gcaagtatgt tatgtagagc cttcaagaag accagcagat ggaagatatg
    21481 gtgaaaaccc aaacagacta tatcaacatc atcaattcca agttatacta aaaccttctc
    21541 cagataatat acaagaatta tatttggaaa gtttaaaaga gattggaatt gacccaagtg
    21601 agcatgacat aagatttgtt gaagataact gggaagctgc tacagttggt gcttggggac
    21661 ttggatggga agtttggcta gatggtatgg aaataactca atttacgtat tttcaacaag
    21721 taggtaatat tgaatgtgag cttgagacag gagaaattac atatggatta gaaagattag
    21781 ctatgtacat tcaagaagtt gatagtgttt atgatttaaa atggaatgat aaaataactt
    21841 atggtgaagt atttaataaa gctgagtatg aaaactcaat gtacgcattt gaattatgtg
    21901 atgcagatat gttgtttaat ctgtttgata tatatgaaaa agaagcatta agacttatgg
    21961 aaaatggact tgtaatacct tcatatgact atgtgttaaa atgctctcat gcatttaata
    22021 cattggatgc aagaggtgca ataggagtta gtcaaagagc ttcatttata ggtagagtta
    22081 gaaatatggc aaagactgtt gcagaaactt ttgtaaaaca aagagaagaa atgggattcc
    22141 ctcttttaaa ggacggtgac aaataatgaa aaattatctt ttatttgaaa tcggtgttga
    22201 agaaatgcca tcaagatttg taggcagtac actagaacaa ttaaaaaaca atcttagtaa
    22261 attatttgat gaaaatagaa tagcttttga taaaataaat gcttatggga caccaagaag
    22321 acttacttta gtagtcgaag gattgagtga tagacaaagt gatttagaag aggaaataaa
    22381 gggtcctgct aaaaaaattg ctgttgatgc agaaaataat ttaacaaaac cagcattagg
    22441 atttataaaa agcaaaggat taagcgaatc tgacatatat tttaaacaag ttggaaaaga
    22501 agaatatata tttgcgacta taaagcaaga tggaaaagaa acttcagaag tactaaaaga
    22561 catattacca gagactataa aatctgtagt attcccaaaa gctatgcgct ggggaggaaa
    22621 aaatcttaaa tttgcaagac ctataagatg gatagttaca ttgttaaatg ataaagtatt
    22681 agagtttgat ttagaaggaa taatatcttc taatgtaaca aaaggtcata gatttttagg
    22741 tgaaagtaca atagaagttg attctataga agattatttt gaaaaattag agaaaaatta
    22801 tatagtttta gaccaaaaca agagaaaaga aatgataaga aaacaatgta tagaagtggc
    22861 aaattcttta ggtggagaag ttgaatttga tgaagattta cttgaagagg taacttactt
    22921 agttgaatat ccaactgctt tttatggaga atttgatgtg gattatataa aactaccaaa
    22981 agaagttgtt ataactccta tgaaacaaca tcaaagatat tttccagtac ttaaagaagg
    23041 aaaactgtta cctaacttta tagctgttag aaatggtgat tcttacagaa tagacaatgt
    23101 taaagctgga aatgaaaaag ttttagaagc aagacttgca gatgctttat ttttctatag
    23161 agaagatact aagagaaact tagaaagcta catagaaaaa ttaaaaactg ttgtattcca
    23221 agtaaaacta ggaactattt acgacaaaac tttaagactt gaaaaattaa gtgctgatat
    23281 acttgatagt ttaggtttag tagatgaaaa ggcagatact ataagggctg ctaaattatc
    23341 taaggcagat ttagttactg gaatggtagg agaatttgat gaattacaag gttttatggg
    23401 aaaagaatac gcaaaagttg gaggagagaa tgatgttgta agtgaagcta tttttgaaca
    23461 ttatcttcca agatttgcag gagatatact tcctaagact aatgcagggg ttgccttatc
    23521 aatagctgat aagttggatt caatagcagg tttctttgct ataggaatac aaccaacagg
    23581 ttctcaagac ccatatgctt taagaagaca agctttaggt atacttagta tacttatgga
    23641 cagaaaagtt gctgtggata taaaagtact tattgaacat gctttagaca attattctga
    23701 attagatttt aataaagaag aagttgttga gcaaataatg aatttcttca atgagagagt
    23761 aaaaaatcta tttaaagatt taggaataag atatgatgtt gttgatgctg ttttaagttc
    23821 tgatataaat gatgtttctg atatgcatat gagagcttta gagcttaata attggctaga
    23881 aaaagatgaa ttagtggaga tgcttactgc atttaataga gtttctactc tagctcaaaa
    23941 agcagaaagt gataaaattg atgaatcttt attaaaagaa gatgctgaaa ttaaacttta
    24001 caatgaattt aaacaagtaa aggtaaaagt taatgaatta ttaaaggata agaaatatgg
    24061 tattgcttta gatgaatttg catctttaag accagtagtt gataatttat ttgatacagt
    24121 tatggttatg gataatgatg aagctattaa gaacaataga cttgctttac ttaaacaagt
    24181 atatgatact atgctaggaa tttgtgattt atctaaaatt gtttataaat aaaatttaaa
    24241 ctatttataa gaaataaggc tgtctcaaaa tagagatagt cttatttttc attgttgaga
    24301 tgatgaaaat atatttgatt tcatagaaaa agagtgtctc ataaactaaa aagttcattt
    24361 tgagacaccc atgctttttg taagtaaata taataaatta tattttatac ttatcagtta
    24421 ttttgtttaa aatattatca tttgaattta cccattcata aaaattgcct gatgatgcgt
    24481 ccgatatttt ataaagcatt tcaggaatat cactagcttt aaaatctcca agtgattttc
    24541 ccaatctagt cttacctatt tcaaaactgc ctccaacaaa taattcaaat gcatctgtag
    24601 atataccatc aacattcttc tttttaccac ataaacctat gctaccaact tgatgaacac
    24661 cacatgaatt taaacatcct gatatatata acttaggtgc tttatttaaa atttctttat
    24721 tattttgtaa tctaaaataa tctatgattt catgtaacat tttctgacta ttttgtatgc
    24781 ccatttgaca aattggaaca cctatgcaag atatactttg ttctaattga gaattacaac
    24841 taatagtttt acttatttct aatattcttt ttgcttcatt tccatttaaa tttaaaatat
    24901 ataatccctc tgtcattcct agtctaatca taggattttc aatattatct aattctttaa
    24961 gtaaagtact taaatccttt gttaacaaaa tacctccaac tggatgtata tatacagtgt
    25021 ataaaccatc ctgtttttga ggtattagtc tagaatcctg tatatctatt ttaaccccag
    25081 gtttagagta atctatttct tcaatattga gttcaagact accattttct ttttctaatt
    25141 tatagtattc tttaaatttt tctaagaata atttttcacc aagtgattcg accatatatc
    25201 taaccctagc tctgttttta ttttcataat ttccataatc cataaagaat ttaatcatac
    25261 cttcaacaca atataaggca tctttcggtt ttataagttc atcaagttct aaagcaactt
    25321 tgggttgttt acctagacct ccacctaaga aaactctgaa atatggttca tcatttttca
    25381 aagtagcaac aaatcctaag tcttgtatac tacaatgagc agtatctgtg taacaattag
    25441 aataagaaac ttttaatttt ctaggtaaat ggtatgtagt agcatttttg ataaaatatt
    25501 tatcagtagc aactgcatat ggagtaacat caaagacttc actagggtca actccagata
    25561 atggagataa tccgacattt ctaggataat taccaccacc acctctagtg aatatatcat
    25621 tttttattcc ttcttccatg atatcaacaa ttgaatttat agataaatcg tgtaattgta
    25681 tagcttgtct agttgttaag tgtatcttat ctaagttgtg tttaatagct atttcataga
    25741 ttttattaag ttgatactga gataaaactc cagcagatac tctaagtctt atcataaaag
    25801 attttttgtc tctttgagca taaacaccat atccaccaga aaatccctta tattgcattt
    25861 tatttatttc tccatttaaa aattttgaag aatattcttt aaaattaggt agttcattta
    25921 acaatatctt tttaaaatta tccattattt cacctcattg ttagtcttgt ataaaaatat
    25981 atctattgta taatagatat atatattatt atctagtcag gataaaaata taacagaata
    26041 attctattaa aagtaagaat aataaggaca tagtgagtat tttgttttta ttttacaaat
    26101 taagtataat atttttgttt tata
//
LOCUS       DAEPXW010000053        25991 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.054, whole genome shotgun sequence.
ACCESSION   DAEPXW010000053 DAEPXW010000000
VERSION     DAEPXW010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25991
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.054"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(105..1112)
                     /locus_tag="KRM55_002219"
     CDS             complement(105..1112)
                     /locus_tag="KRM55_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH1594459.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            1340..2224
                     /locus_tag="KRM55_002220"
     CDS             1340..2224
                     /locus_tag="KRM55_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1594460.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDTYFK"
     gene            2426..3976
                     /locus_tag="KRM55_002221"
     CDS             2426..3976
                     /locus_tag="KRM55_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1594461.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            4005..4652
                     /locus_tag="KRM55_002222"
     CDS             4005..4652
                     /locus_tag="KRM55_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBH1594462.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(4794..5054)
                     /locus_tag="KRM55_002223"
     CDS             complement(4794..5054)
                     /locus_tag="KRM55_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HBH1594463.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            5271..6554
                     /gene="hflX"
                     /locus_tag="KRM55_002224"
     CDS             5271..6554
                     /gene="hflX"
                     /locus_tag="KRM55_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH1594464.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIETALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            6562..7239
                     /locus_tag="KRM55_002225"
     CDS             6562..7239
                     /locus_tag="KRM55_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBH1594465.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            7325..7768
                     /locus_tag="KRM55_002226"
     CDS             7325..7768
                     /locus_tag="KRM55_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1594466.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            8073..8717
                     /locus_tag="KRM55_002227"
     CDS             8073..8717
                     /locus_tag="KRM55_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBH1594467.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(8803..9180)
                     /locus_tag="KRM55_002228"
     CDS             complement(8803..9180)
                     /locus_tag="KRM55_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH1594468.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(9180..9566)
                     /locus_tag="KRM55_002229"
     CDS             complement(9180..9566)
                     /locus_tag="KRM55_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH1594469.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            9745..10500
                     /gene="nadE"
                     /locus_tag="KRM55_002230"
     CDS             9745..10500
                     /gene="nadE"
                     /locus_tag="KRM55_002230"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBH1594470.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            10583..11302
                     /locus_tag="KRM55_002231"
     CDS             10583..11302
                     /locus_tag="KRM55_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1594471.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(11469..12473)
                     /locus_tag="KRM55_002232"
     CDS             complement(11469..12473)
                     /locus_tag="KRM55_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH1594472.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSNSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            12739..13635
                     /locus_tag="KRM55_002233"
     CDS             12739..13635
                     /locus_tag="KRM55_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBH1594473.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENDIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHINIKSDSCNC"
     gene            13773..15035
                     /locus_tag="KRM55_002234"
     CDS             13773..15035
                     /locus_tag="KRM55_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594474.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            15111..16304
                     /locus_tag="KRM55_002235"
     CDS             15111..16304
                     /locus_tag="KRM55_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH1594475.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKYTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            16933..17727
                     /locus_tag="KRM55_002236"
     CDS             16933..17727
                     /locus_tag="KRM55_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH1594476.1"
                     /translation="MESVMENLNNLKVELKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGVFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            17822..19162
                     /locus_tag="KRM55_002237"
     CDS             17822..19162
                     /locus_tag="KRM55_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1594477.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            19299..20531
                     /locus_tag="KRM55_002238"
     CDS             19299..20531
                     /locus_tag="KRM55_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH1594478.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     TLIESGIVTMNKEACEIC"
     gene            20571..21713
                     /locus_tag="KRM55_002239"
     CDS             20571..21713
                     /locus_tag="KRM55_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH1594479.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            21724..22518
                     /locus_tag="KRM55_002240"
     CDS             21724..22518
                     /locus_tag="KRM55_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1594480.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            22529..23551
                     /locus_tag="KRM55_002241"
     CDS             22529..23551
                     /locus_tag="KRM55_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH1594481.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            23650..25026
                     /locus_tag="KRM55_002242"
     CDS             23650..25026
                     /locus_tag="KRM55_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH1594482.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(25358..25702)
                     /locus_tag="KRM55_002243"
     CDS             complement(25358..25702)
                     /locus_tag="KRM55_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594483.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
BASE COUNT         9829 a         3047 c         4837 g         8278 t
ORIGIN      
        1 aaaatatcta atatatttgg tctgtaggtt aaataaaagt acctttagac caaatatatt
       61 attaataact taataacatc ttaaaaccta tttatttata ttatttacaa catccattta
      121 ataaatacac cataacctac agctgggtcg ttttcaattg catgtgacac tgctccgatt
      181 attttattat cttgaactat tggagtacca ctcatacctt gtacaatacc accagtttga
      241 gctaaaagct ttttatctgt aattttaatt ttaaaacttt tactttctgg atgtttttgg
      301 ttttctatat ctataatttc aatattatat tttttacact tattaaagtt atcttgtaaa
      361 attatttgag cttttcctaa tttaacttca tctaaagatg ctactttata tttttttaac
      421 ttggaaatat caaagttatt aatttgacct cttattccaa aatcagtatt ttctgtaaag
      481 ctaccaataa tattttctcg ttttgcattt atacatccaa cactaccttt ataagatttt
      541 tctatattaa ggtgcttagt tgtagaaatt gaacctgttt taataggtat ttttcttgca
      601 ttaccaacac ttattggatg acctacagct ccaaactctg atgtatctgg attgatatac
      661 gttaaagtag caaatccaga aagtaaattg ttaaaactaa ttttttctaa tatgtgtttg
      721 gtagttttca ttgttataag ttgtccacct ctatttaata aaatagatac ttgtttttct
      781 tctggtaaag catttaaggt attggcaaag tcactatatc catcaacttc agcattattt
      841 acctttacta tagcatcacc taatctaaat ggagatgctt ctccaggatt tctaactatg
      901 atatttttta attctgcgtc aatttgaagt acgtttccaa ttggtattaa atattcaggt
      961 tcattttttt gtaaattttg tgcataaatt aaattatttg agaaaaaata taataaaaat
     1021 aaaaatgtta aaacaattgt aaattttgac ttagctaagt tggttttttt acttaaagta
     1081 ttatttttaa aatgaaaatt tttaagttgc ataaaacacc tctttcttat taaattattt
     1141 taataataga attgaagttt tcttgctgct tctatattat gttgtgcaag aatcatgttt
     1201 tgatgcttgg aaaactagct caataacacc ttagttttca taaaaataaa taaaataaat
     1261 agtgtatatg ataaaataaa tacatattca tataaataaa aataaacaat aactgtctag
     1321 cataagaaag gagcaaaaaa tgaaaaaata tagattgtta gttacttgta taattgccat
     1381 gggaatcata attataggaa catcaaatcc agttagcaat ttttacaaga ctacaaattt
     1441 gattagttca ggaaatatca caaatgaaaa agcagataaa gatgaaaatt caaacaaaaa
     1501 taataaagat aaaaatgaag acaaatctaa ttctaaaagt aataaagata agtcatcaga
     1561 ggacaaatcg tcagataata aaaatgaaat tcaaaaaaat aaaaaacttt taatttgtat
     1621 agacccaggg catcaaggaa aaggagatag caatttagaa ccagtagctc caggttcttc
     1681 ctctaaaaaa gcaagagtat cttcaggaac agagggtatt gctacaaaaa agccagaata
     1741 tgttttaaac ttagaagcat ctcttgtttt aaagagtata ttagaatcta aaggttataa
     1801 tgtaataatg actagagaga cacatgatgt aaatataagt aattcagaaa gagcaatact
     1861 tgctaatgac aaaaaagcag atatggttgt aagaatacat gcagatagtt taaataattc
     1921 ttcaaaaact ggagcatcta tattgattcc tgaaaaagat ggaaaatata cagctcctat
     1981 atatgaagaa agtaataaat gtgctgaatt tatcaaacag aatatggaac aatcaggtat
     2041 acaaatcaat ggaatcgttc aaagaggtga tttgactgga ttcaactggt caaaagtacc
     2101 agctgtatta gtagaaatgg gatttatgag taactataat gaagaccaaa tgatgtcaaa
     2161 tccagactac caaagaaaaa tgatgcagtg tatagctgat ggattggata cgtattttaa
     2221 ataagatatg aatagagaaa aagttaggtt ggtattattt tcctaatttt tatctctatt
     2281 ttttattgta cataacacaa agaagaagtt tattttaggt taaattgtcg taaatataac
     2341 taaaaatatt gggaatactt gatttaagtt taaaaagaat atattatagt atagaatgtg
     2401 taaaattttt ttgagaggtg ttgaaatgct agtagtagaa aatgtgagtc atggatttgg
     2461 tgcgagaaca atattagaaa atgtatcctt tagacttaga aaaggtgaac atattgcact
     2521 agttggtgct aatggagaag gaaaatcgag ttttttaaat ataataacaa agaagcttat
     2581 gccagatgct ggaaatataa aatggtcttc aagagctaca gtaggttact tagaccaaca
     2641 tacggtatta agcaagggaa aaactataag agaagtgctt agagaggctt ttaagcatat
     2701 gtttgactta gagcaagaaa tgattgctat gtatgacaaa atgggagaag ctagtgatga
     2761 tgaaatgagt aagcttcttg aagaaacagc agagatacaa actatacttg aaaatagtgg
     2821 tttttatatg atagatgcaa agatacaaga agttgcaaat ggtcttggtc ttggagaaat
     2881 tggtcttgat aaagatgtaa ctgacttaag tggagggcaa agaacaaaag tacttcttac
     2941 taaacttcta cttgaaaatc caactattct tatattggat gagcctacaa actatttaga
     3001 cgaagagcat ataacatggc ttactaagta ccttcaagag tatgagaata gttttgtctt
     3061 agtttctcat gatattgaat ttataaataa tacatgtaat gtaatatatc atatggaaaa
     3121 tggagagtta aatagatata aaggaaatta tgatgaattt gtaagactta atgatataaa
     3181 gaaacgtcaa gaagaacaag cttatgataa acaagttgaa gaaagaaaaa gactagagga
     3241 ttttgtagct agaaataaag ctagagtagc aactagagga atggctaaca gtaggcaaaa
     3301 gcaacttgat aagatggaaa tattagaaag accaaaagaa aaaataaaac ctacttttgc
     3361 ttttaaagat gctagagcag ctagtaaaat aatttttgaa acagaaaatt tagttttagg
     3421 gtatgatgaa gcattgacaa aaccacttaa tttccattta gaaagaggaa aaaagattgc
     3481 cttaaaagga atgaatggta ttggaaaatc taccctatta aaaactttac ttggaataat
     3541 aaaaccattt gaaggaaatg ttaaattagg tgactatttg gaagttggat attttgaaca
     3601 agagagttca agagaaaata gtaatacacc tatggatgaa gtttggagtg aatttccagg
     3661 gcttacaaac tttgaagtta gacaggctct tgcaaaatgt ggacttacaa atgaacatat
     3721 aacgagtcaa atgagagtat taagtggtgg agaagctgct aaggttagac tttgcaaagt
     3781 aatgttaaaa aatataaatt tcttagtatt agatgagcct acaaatcatt tagatgttga
     3841 ggcaaaagat gaattgaaga aggctatcaa agagtttaag ggaacagttc ttttagtatg
     3901 tcatgagcca gaattttatt cagaaattgt tgatgatgta tggaatatag aagattttac
     3961 aactaaaatc gtgtagtgat ttaacttatt gctgggggga tttcatgaaa aagtttctaa
     4021 atgtactttt ttcaatttgt attagtattg ttataatagt aggtgttatt aattttactg
     4081 ttggatttaa acaactttat tattttgaca ttgattactt aaatatatca gagttatctg
     4141 gtttatctaa agatgatata aaattgaact acgattatct aattgattat aacttaaata
     4201 agaatgtgtc tgagttcaaa ttaccaacat taaaatcttc tccacaaggg aagatacatt
     4261 ttgaagaagt caggaatata tttcaaaata taaataaatt agctaaatta ttattggtag
     4321 tttctttagt aggaattata ttgagtgtaa aaaataaaaa tataaaaatc ttaaaaacta
     4381 catcaataac acttataatt atgccattat tattaacagt tccaatttta ttaaattttg
     4441 aaaagtcatt tattattttt cataaattat tatttagaaa tgattattgg atatttaatc
     4501 ccgatttaga cccagttata aatatattgc cagaggaatt tttttttcac tctggaatga
     4561 tgattttaat attaattttg ttagtaagta tagtactgtt tgtaatgtat aaattatgta
     4621 aatctttatc aataaaaata tttcaatgtt aaatagaggg atatttttat ttccaaaata
     4681 agataataaa aaaggattag attaaaagtt atacaataaa aatagctgtg caataatatt
     4741 tagactatga aagtagttga aaaatattta tgcacagcta tttataatag aatttacttt
     4801 ttactagtga ttttaactaa atcttgaaat ttactcataa tgtaattgta attatctttt
     4861 ttatgaggta atatacaact actgcaatct ttgatacctt tatctgtata cttaaagttt
     4921 ccaccacagt tttctcctaa agcatacaaa ggacaatagc aaaatagaca gttaaactct
     4981 tctggtttat tagttttatg acaagggaaa aattcgcaat ctttgtgatt aaaaaactta
     5041 taattttcgc ccatattttc ctcctaatta aataaaattt aaatttttta tactatataa
     5101 gaatttggtg ataatataat tatactaaat aattttatga atagtcgata atatagtatt
     5161 attaatcata gtattaatgg tataattagt caacagaaaa ataatgtaaa aataatgtaa
     5221 gtgtattttg taattagaat atgttttata acaaaaaatg aggtgattaa gtgaaagaaa
     5281 ttcaagaaaa agcacttctt gtaggtctga atttgactac aatagtgaaa aaaaatgatg
     5341 atatagacac taatgaatct atggaagaat taaaagaact aacaaaagct gctggggcag
     5401 aagttgtagg tagcttaatt caaaataaac actctgtaga tgcagcttat tatataggaa
     5461 aaggtaaagt agaagaaata agagcctata gtgactcttt agatgctact ttagtaattt
     5521 ttaatgatga attatctggt gctcaaatca gaaatataga gaatgttgtt ggaagaaaag
     5581 taatagatag aactacttta attttagata tatttgctca aagggcactt agcaaagaag
     5641 gtaaattaca agttgaatta gcacaattaa aatatagatt gccacgactt tatggaatgg
     5701 gtggtgagat gagtagaaca ggtgcaggga ttggtactag aggtcctgga gaacaaaaac
     5761 tagaaataga taagagacat atacttaata aagcagcaga tataagacgt gaacttaaag
     5821 aagtaaaaaa gaatagagag acacagagag ttaagcgttt aaagtcaaat ataccgattg
     5881 tagcacttgt tgggtataca aatgcaggaa aatctaccct gttgaacgaa ttaataaaga
     5941 cacacaagga ttatgaacaa gaaaaagaag tttttgtaaa agatatgctt tttgcaactt
     6001 tagatgtgac tttgagaaag gctcttttgc cgaataaaaa agaattttta gtagtagata
     6061 ctgttggatt tgtaagtaaa cttccccatg atttagtaga agcatttaag gcaacattgg
     6121 aagaagtaca gtatgcagat ttaatcttac atgtaattga tgcaacaaat actagttatg
     6181 aattgcaaaa aagtacgact gaaggtgtat taaaagaact tggtgtaaat gataaaaaac
     6241 atatacttgt atataataaa gtggacaagc tagaattgga tatatatcct aaaagtcaag
     6301 aagatattgt gtatatttct gcaaaacaag gcataaatat ggataagtta ttaaatatga
     6361 tagaaactgc tttaatggaa aatacttatt cagtaagttt gatgttacct tatgagagag
     6421 gtgatatatt tagtagaata aaagataaat ataatgtgga gaattttgag tatggggaaa
     6481 gtggtataac gctagatgta gatttagatg aagaagattt taatatctat agagagtaca
     6541 tactagaaaa ataggttgaa tatggatata aactgggaaa atatagataa tcttgaagat
     6601 tattttataa cctatcttct ttataaagaa tctaaaacag tatctcaaat tagtaaaatt
     6661 agaaatattt caagtactga agcaagtgag caacttatac aagcaaagtt aaaaataaag
     6721 gaaatgcaaa aagatgattt tgaggcatct aaggatattt tggataaatt tctagaacta
     6781 gataaaatta agagacttga ttttatggat agcttagatg acgaaaaaat ggtatacttt
     6841 aagagaaagg ttttcaaaag aatccttgta gaaaaaaatg ctgaagattt aattgtttta
     6901 atttgggcga caggtgagct aaaagatgat aggtttttga aattgcttca tcagctcaca
     6961 aaccacagac actcagatat tagaagaata acttattcag caatcagaaa gattgaatca
     7021 ccaagtagta gagaagtact gcaaaaaggt ctctacgaca aaaatgcaca gactagacag
     7081 tactgtgcaa aagctctttc aaaattggga gatgaaaaca gtttaaagat tttacagcag
     7141 ttgaaagaca agaataagaa ttttgaaaaa gaatatgtgc ttagagctta tgacgaagcc
     7201 attaagtcat tggaaaatgc aaaaaatttg aaaaagtaat tttttattaa agcaatttgt
     7261 ttacttaatg atgtatttct aaagtttaac aaggtaataa ataaattaat gggaggggtt
     7321 tcaaatgata gtaagacgtt gtgcaggtgg agtagtgttt tatgctaata aagtacttat
     7381 tgtaaaaaat gataggggtg aatggacact tccaaaagga aagatactag gagggggact
     7441 tccatatgag agtgctgttc aaagagttaa agtagaaact ggcatagatg ctaaaatgat
     7501 agatgtggct ggcgatacta tgtatgaatt tttctcaaga agtagacaac aagaagtttg
     7561 taatgcaata atgtggtatg ttatggaagc ttgtaacact gattgtgtac ttgctcctga
     7621 atttcaagaa ggtggatttt ataaagtaaa ggatgcttta gaaatgttat cacatcataa
     7681 agagcaagct ttagtagaag tatcttataa aaagtttaag gaattaaaga aattagtttc
     7741 agagggcgat gatgttccag caaattaatt gtgaatttag aggattctga ggaagggata
     7801 gccccttcct tttttaattg aagcagtttt aagcgtaaat tatatagtct ctttaaacta
     7861 tgatttatca atttagagat ttagtagttt atatttaaaa tcagtaagat atatttaaaa
     7921 taaaaattaa aaagtataca attttattat ataattgtct tatgatgttg attaaagaat
     7981 tattaaaagt ccatttattt ttaaatagaa taattttata aatatatatt tgatgtgtat
     8041 attagaaaat gattaaaata ggaggaaata caatgagcaa ttacaggaca ttacatgaat
     8101 ttggaacgga tgaaataacg attgaaaagt ctgtttttat tggatatgct aagcctataa
     8161 agagtgaaga agaagcatta gagtttataa atgaaataaa gaaaaagcat aaagatgcaa
     8221 ctcacaatgt gtgggcttat actgtaggta aaaatatgaa tatacaaaga tatagtgatg
     8281 atggagaacc acaaggaaca gctgggatac ctacattaga ggttataaaa aaagaagatt
     8341 tgagagatgt agcggttgtt gttactaggt attttggagg aacaaaatta ggtgcaggtg
     8401 gtctagttag agcttataca aaaggtgcta aactgggact tgaagcaggt aagataattt
     8461 ataaggtaat gtatcaagaa gttaaggtta agatagatta tactcaactt ggaaaagtgc
     8521 aaaatgagtt aatgaatttg gggtatttta taaaagatac tgtatatgag gataatgttg
     8581 aaatagtagt atattcaaga ttagaagatg tagagaaatt atcagaaaaa atgattgata
     8641 taacaagtgg aacaggaaaa atagttttag gagaggaatt ttatttgtct gaacaaaatg
     8701 gagaaatttt aatataatct aaaaggttat tagaatagtt aatacctcaa atagccaatt
     8761 agtattttta agtgaaaagc cattaaattg atttaatcta aatcaattta atggcttttt
     8821 atcggatttt gcacagaatc ctttttttac ttcaaataaa ccgactaaaa gtaaaaatat
     8881 cccaaatatt ttttttaata tatctgaaga cagataatta gctaatagtg aaccaaatac
     8941 agctcctaaa accccaaaca cagctatagg tataaccaat ttaaaaatta catttttatt
     9001 ttttatatgt atagcaagtg ctataagtgt catagggata gatgaaagta aatttacgct
     9061 ttgtgctatt ttagtgtcta tgccagcaag taaaacgagt gcaggtataa ggattgttcc
     9121 tccacccatt cccattcctc caataattcc tgcaaaaaat ccaattagag caaataacat
     9181 taaaacacca tccttaatgc tgcaattatc ataattattc caaaagaaat tctaagaaac
     9241 tttccagtaa ccttatttag taatttagct cctataatac caccaagaat acttccaact
     9301 gcaactttaa ttgttaagtt aacatcataa gtacctttag atacatataa aacagaactt
     9361 gctgtcgtta agaatattat tatagaaaga gcagttgcat gagatttatg ttcttctacc
     9421 ttaacgatgt catttaatat tggaactaaa agagtacctc ctccagaacc aaaaactcca
     9481 tttataaatc ctgtaaaaac tccaattatc gtatttttta agttaaaatc aaagtatttt
     9541 ttctttaaat catcagtttt tttcataaaa atcaccttct gaaatagttt taccaaaata
     9601 ggcaaattat atttatataa aataagatta aatataatct ttcatgtttg tttaattttg
     9661 cataaaaaaa aacatattaa aacaacatat taatatatgg tataatatat taaaacaaag
     9721 tagcaaattt gagaggagat aacaatgtca aatataaaaa tacaaataga caaaactgta
     9781 gaatggctta taaataaggt taatgaggca aatgcaaaag gattaattgt tggtgtatct
     9841 ggaggaattg attcggcagt agttgctaat ttaattaaaa aggcatttcc agaaaactct
     9901 atgggagtta taatgagcat aaaaagtaat cctcaagata gagaagatgc acttaaggtt
     9961 atagagggat gtgatataga ataccttgat ttagacctta tagaaccaca aagtgctata
    10021 ttagacatgg tagtaggaaa tttaaaagat aaacatttat atagagaaga atatttaaag
    10081 atgacagatg caaacttaag agcaagagta agaatgagta caatttatac aattgctaac
    10141 aatctaggat atctggttgt tggtacagac aatgctgcag aaatacacac aggatatttt
    10201 actaaatttg gtgatggtgg agttgatatt ttacctattg caaatttaac taaaggagag
    10261 gtgtatgaat gggcaaaaga gcttggtgtt catgaagatt taataaacaa agctccttca
    10321 gcaggtcttt gggaaggtca aacagatgaa gatgaaatgg gaactactta caatatgata
    10381 gatgctgtat tagaaggtag attggatgaa gttcctaaaa gagaccaaga gataattgaa
    10441 agacttcata gattaagtga acacaagaga aaaacgcctg cacaacctcc taagttctaa
    10501 tttactattt ataagatttg tgataaaatt tacaagtgat gaaaattaga ataattaatt
    10561 gtacgtatta aggagtggaa atatgggacg tataggtaat ataattaata gaaaaggtaa
    10621 acaagatgct caaagagcaa agatatttac taaacatgct agagcaatag cagttgcagc
    10681 taaagaaggt ggagcagacc cagagtacaa tgcagcgtta aaaacagcta tagaaaaagc
    10741 taaggcagat aatatgccaa atgataatat agatagagct atcgctaaag gtgctggagc
    10801 aggtgctgga gaagactatg aaactatagt ttatgaagga tatggacctg gtggagttgc
    10861 tgttatagta gaaactttaa ctgacaacaa aaacagaact gctggtaacg taagatacta
    10921 ttttgacaaa aacggaggaa acttaggaac tagtggatgt gtgtctttta tgtttgataa
    10981 aaaaggacaa atattagttg gtttaggaga tggagtttca gaagaagaat tgatggatgt
    11041 tgcattagaa gcaggagctg aagatttcat aacagaagaa gatggttatg aaataataac
    11101 tacaccagaa gatttttcta gtgttcgtga tgagttaaaa gctaaaggat atgagtttat
    11161 atctgctgat gtgaagatga tacctcaaac tacaactgta ttgactgaag aatctcactt
    11221 aaaaatgatg aataaattag ttgatatgct tgaagaagat gatgatgttc aagatatata
    11281 tcataactgg gaagtagaat aaatagtata agcatattga aatttataag tatttaatca
    11341 attttaacat gtgataaatt ttatagaata agaaacacta aaatagacat acgcacctct
    11401 aacctatatt tgcataataa tatgtaagca taggtaaggg gtgtttttat atttataggt
    11461 taagaaattt aaagtaaatt ttgagctgga ctcgattgtc tataaataat tgatgggtat
    11521 ataacttgtt gctgaatacc atttatacgc ccagttactg tatcaataat catcctaaga
    11581 ctacgttctg ctgtctcttc catttttaaa tctataactg tcaaaggagg aatacttctt
    11641 gccattagtc gtgaaggtcc attacttgct gcaaatattt gaatatcctc tccaattaca
    11701 attcccgatt catgaaatgc attcatcata ccaagagcta ccacatcatg attacaaaaa
    11761 attacttttt ttagtgaatt ttttgcaagc attttttgag caatatcata cccactatct
    11821 attttattag aacaataata tatagaattt gatagatgta ttccatgttc tttacatgtt
    11881 tttaaaaaag atttacccct taaagtcata catgtaaagg aagttgggtt gaatacaaca
    11941 gcaatatcat ttttaccatt ttgaatagca tgtaaagctg ctatacgacc agtttcctca
    12001 ttatcaatag atacacttga aaaaccaggt atttcacgat ttacaacaac tacaggaatt
    12061 ttaggtttat tttttactag atattctata tcatcagcat tgatacctgt taaaacaatt
    12121 ccatcataat aattatttgc aaaaaagtat tcatcatcac atagatgacc aactttgtaa
    12181 ggtcgtatga tgatatttat gtttaaatgt tctaaagaaa ttatgtggtt tattgcttga
    12241 agtatattgg ttgatgccaa ctcaaatccc tcatcctgcc aataaaaagc tattttaata
    12301 ttattatgtt taataggagt agagcgttta tatccaagct tatcagctga atttaatata
    12361 agctcttgtg tatgtagcgg aatcctgcgt tcatttcctt taccacttaa gacgtacgag
    12421 acagttgctg aagaaagacc acagtctttt gcaatatctt tgattgttgc catgataaaa
    12481 tcctccttaa atagttgctt aaatttgctt ataccaataa tcttaacata tattcaacta
    12541 aagaacaata ttctacaagg tgcatatttt acaggattag aataaataaa tttaaaaaaa
    12601 cttcttactt atgttgacat aatttagttt ataggattat aatatgctta aataagctta
    12661 tgattaactt aaattaagca aagttaagca aaaacatgca atgctagctt gcaatgtgac
    12721 tgtaaagggg gaaaaggtat gagtaaggta aatatatttg aagttggtcc tagagatgga
    12781 tttcaaaacc tgaaagagtt tttagaaact gataaaaagc ttaagattat tgatggtctt
    12841 attgcttcag ggattaaaca acttgaaatt agttcatttg taagcccaaa agcaatacct
    12901 cagatgaaag atgcaaaaga agtagcaact tattgtgtag aaaaatatcc tgatgtgaaa
    12961 ctttatgcat tagttccaaa tttatacggt gctaaagttg catgggagtg tggtataaga
    13021 gatatatcct atgttatatc tttgagtgaa actcataata aaaaaaatat aaatcgtacc
    13081 catgaagagt ctattgatga gcttaaaaaa ataatgaata cttatccaga catgaatata
    13141 tgtattggaa tggctactgt atttggatgt ccttttgaag gtttaccaaa aattgaagat
    13201 gccataagat ttgctaaacg cctttgggaa aacgatatca gggagataaa tctagcagat
    13261 acaataggga ttgctgaccc taagcaagta agagaaacta ttagtgcatt agttgaagct
    13321 ttaccagagt gcagatggca agtacatatt catgatacta gaaatatggg aatggttaat
    13381 actcttgtgg ctattgaatc tggaattact actgttcagt ctacacttgg aggattagga
    13441 ggatgcccat ttgctcctgg agcatctggc aatactgcaa ctgaagattt agtatatatg
    13501 cttgaacgta tggggtatga tacaggagtt gattttgtta aacttcttga attatcaaag
    13561 tatcagaaga gttttgtaaa tggagtatat agtggtcatc atataaatat aaagtctgat
    13621 agttgtaatt gttagttcta ttgattaatc gattaaaaaa atatgttgat taaaaaaata
    13681 tgctgattgg taaaatagat ttattgataa aaaatataaa ttataaaata cattatctaa
    13741 taaaacaaat aaaaaaattg agggggatta gtatggatat tatagcttta cttttatttt
    13801 taggagttat tattattgca tttgtacgta agaataatgc aggtattttg gctctagcta
    13861 ttggtgtcat agctgttaga atttttggaa tggatgataa agaactttat ggagctataa
    13921 gcaactcaat gtttactaca cttgttggta taacactact ctttgcaata gtgaactcaa
    13981 caggagcatt aaagcttgtt gcagaaaaaa ttgtagctgc ttctggtaaa cgtgtttggc
    14041 ttatacctat agcagttttt atagcaggat ttgttgttgc tggtgttgga cctggggcaa
    14101 ttccagcact tgcaattatc ccagcaatgg ctgttcctgt agccataaca gttggttata
    14161 atcctgtaat gcttgcactt ataggtgaat gtggattaat ggcaggtcgt atgactccta
    14221 ttactccaga aggtcaaatt ataacaaccg ttgcagaagg ggttggaatt gaaaatgtta
    14281 tgcctactat cttagcctgt caaactcttt ctacaattgt attttcaata gtattgttta
    14341 taattttcaa aggatataaa cttaaaaaac ctataaatgt tatagatagt aagcaaatag
    14401 aaaaattcaa tataaagcag ataatttctc taataagcat agtagttatg attgctttta
    14461 tcataatttt tgatatgaat gttgggcttg cagcttttgc agtttcagct gtacttattt
    14521 ttttcaatat tgctgatgaa ggagaatgta tcaaatcaat tccatggagc acgatagtaa
    14581 tggttcttgg agtaggtgca atgatgacaa tcgtagatgc agcaggaggt attgacttga
    14641 tgagtaatgc attatcatca ctgatgaata gtaaaacagc tactccaatt atgagtattt
    14701 cagcaggact tatgtctatg gttagttctg ctttagcagt agtttatcca actatgatgc
    14761 ctatgtgtgt tgatatagct aaggcagttg gaggagtaga cccactagca cttattgctg
    14821 cagttggtgt tggaggttct cttgctggtg taagcccact ttctactggt ggggcattga
    14881 ttttagcagc tatgggttca agtaagaaag actttaataa ggaagaacaa aataaggttt
    14941 ttgtacagct tttcattatg agtgcagttg gcttattggt tattgcagta gtatcaatat
    15001 tatcatttaa tgcaataaca catttaatga actaattaga ataactgaaa ataaatcatt
    15061 aaatttaact tttaatatta atcaatataa tataatttgg aggggaagtt atgaaaaaag
    15121 gagcattaag caatataaag gtacttgacc ttacaagagt tcttgcaggt ccatattgta
    15181 caatgatgtt ggcggatttt ggagctgatg ttataaaaat agagatgcca agaaaaggtg
    15241 atgatacaag aggttttgga ccttttgtaa atggagagag tttatactat gcaaatataa
    15301 atagaaataa aaaaggtatc actctaaacc ttaaatcaga agaaggaaaa aatatatttt
    15361 tagaaatggt aaaacatgct gatgttgtag tagaaaatta cagaccaggt gtaatggaaa
    15421 agttaggtct gggttatgat gagttggcta aagttaacaa tcaaataatt tatggagctg
    15481 tatcaggatt tggatgttat ggaccatatt cagaacgtcc aggttatgat attattgcac
    15541 aggcaatggg tggtcttatg agtataacag ggcaagaagg aggagaacca acgagagttg
    15601 gtaatgctat gggtgatgta ctaggtggaa tgaatttaac tattggtata ctcacagcac
    15661 tcaacgctag aaaaataata ggaaaaggac aaagagtaga tgtttccctc gttgattctg
    15721 ttgtatcgtc tctcgaaact ggtatacaga gatactttga ttcaggacaa cctgaactta
    15781 tgggtaatag atatgcttca gcctatcctt atgactcttt taaggcaagt gatggaagtt
    15841 ttgtaatagg ctgtggtaat gacaaacttt ttgaaaagtt atgtaaaaaa gttcttttta
    15901 gagaagacct tttaatagat gagagattta aaacaaatct taatcgttgt gaacattaca
    15961 aggctcttaa accagaaata gaaaaatggt ctgttaagta tacaataaaa gaagcagttg
    16021 acttaatatc agaggctgga gttcctgctg ctcctatcta taatcttgat tgtgttacaa
    16081 cagatgaaca tatagcaaaa gcaagagaaa tgattgtaga tattagtcat cctattatag
    16141 gaaatatgaa agtcaatgga aatccagtta agttgatgac aacaaaagct aaaattgata
    16201 tgccagcacc atctctaggg gaaagtaacg aggagattta taatggttgg cttggttttg
    16261 atagtgataa aataaaagat ttaaaagaaa atggagttat ttgattaaaa aatagctaaa
    16321 cacacttgtg actttagtca tgggaggttc agttagaata atatcaaaaa atattaaatc
    16381 aatactgtaa atcaaatata gaattgtcag aagcatttaa gatgggaaaa gctacttaga
    16441 cattgagtct ttgtggcttt tcctattttc attaagaatt ttatattatc agaatagata
    16501 tgtactaaac taaagtatta acaatttaaa ttaatagaaa ataaactacc taattatgtt
    16561 gaataaagac tactttagtg aaaacaaact tatagagatg ctatttaaat tattttaatg
    16621 gaaatatcaa aaatgagact gcattctcaa aaatgagact gcgtttttta agtattttct
    16681 cgaaaatgag acaaaaatat tgttttatgg gttttattga agaaaaattc ttctgtgaat
    16741 tacaatttaa tcaattttaa agttgaaaat tattaaaaat ttagtgaaat ttatgtatat
    16801 ttcgtttatt ttattaaaaa taacaatttt ttactaaaaa taaagaactt caatagtgat
    16861 tggcatagta cttgctattt tatattaaca agaaatgtag aaaaaataac aatgtataat
    16921 ggggggaata tgatggaatc tgtaatggaa aatttgaaca atcttaaggt ggagcttaag
    16981 gacaaagtct gtgttattac tataaataga cctaaagctt taaatgctct taatagtgac
    17041 actcttaggg aactatcaca agttattgat gtagtatcag aaaatgaggc aatattagga
    17101 gttattatta ctggagaagg taaagttttt gtagccggtg ctgatatacg ccagatgcaa
    17161 aactataaaa gtgaggaagg cagaaaatat gcaggttatg ctcagggagt ttttgataaa
    17221 attgaagctc ttgaaaaaac agtaatagca gcagttaatg gatatgcatt aggtggtgga
    17281 tgtgaacttg ctatgagttg tgatattaga attgcatcag aaaaggctat atttggacaa
    17341 cctgaagtta atttaggagt tattccatgt tttggtggaa ctcaaagatt atcaagactt
    17401 gttggaactg gaatagctaa agagttaatt tttacaggga gacaagtaaa tgcagaagaa
    17461 gctaaatcta ttgggcttat taataaagtg gttccaagtg atttactttt agaagagtct
    17521 atgaagatga tgaaccaaat agttgaaaaa gcgccaatag caataagata tgcaaaagtt
    17581 gttattaaca aagggataga tatggattta aagaatgctc ttgaactaga gaaagatatt
    17641 gcaggtttaa cttttgctac aagagataag caagaaggaa tgaatgcatt tatagaaaag
    17701 agaaagccag tttttgaaaa taagtagcta ttataactaa aattggaaca atgtagaata
    17761 tattcaaaat ctaaatttcg tgaaaaaata catatagttt aattttaaaa ggagttaatt
    17821 tatgaatacg ggagtaatta taagtttagt agggattatc atagctctat ctcttctagt
    17881 tgtaatggtt atgaagggaa taaatatttt tattatagca attgtatgtt catcattagt
    17941 tgctataaca ggaagcctaa atgtgtatga tgcacttaaa gtggattata tgacagggtt
    18001 tgttggattt cttcaggcaa atttctttat tttcctaaca gggacattaa tgggaaaaat
    18061 aatggagatt actggtggag caaaatctat tgctaagatg attgtaagat ggattgggaa
    18121 ggataaagca ctactttcta ttccaatagc ttgtggaata ttagcctatg gtggagtaag
    18181 tgttttcgtt gtaagttttg cagtgtttcc gatagcttta gaaattttta aagaagctga
    18241 tttgccacga agatttatac cagcagcttt gacttttgga tgctcaactt ttgctatggt
    18301 tgcaccaggg gcaccacaaa ttcagaatat tgttccagca tcaacattag ggacagatat
    18361 tatggctgga gcagtaaatg gttttatatc atgtgcagta atgtttatag ttggaagtac
    18421 aattttgtac aaaatggttt caaaagaaaa agccaatggt ggtcatttta tagcacatga
    18481 atcagatata tttgatgaag cagaagcaac taattctaag agagaaaatg gtcccaatgg
    18541 tgtaattgcc ttaattccat tgatagtgtc aattttaata attaatgtaa aagttaatgg
    18601 aaaagcgata gtaccaattg aggtgggagt atttattgga gctttattag tatatttatt
    18661 gttaaataaa tatcaagata atactaaaat agttggacat gttggtgatg catgtaaaac
    18721 tacagtagta gcaatatgta atacttgtgc tgtagttgca tttggttcag tagtaaaatc
    18781 agcagttggt tttgacttca tagttaatgc tatgactaat attcctggtc ctcctattgc
    18841 aggggctgca gttggaacta cagttattgc aggtatttgt gggtcagctt caggtggact
    18901 aggaattgca gctccacttc ttggaccagt atttttagcc aagggtgttt ccgctgcagc
    18961 attaactagg actatggcaa tttcatcagc agcattagat tcacttccac acaatggata
    19021 tattgttact gtaacaaatg gtctttgtaa agaaacacat aaggatgcct atatgccaat
    19081 attctgggta actgttttaa ccccatttat tggaaccata gtagcagtcc tactgtttac
    19141 aatgttcccg ggattgccat aggagaaaag ataaaaggta taaattatat tttgatatta
    19201 taaaatcaat tttcaaaata tatacaataa atttcatgtt ttaatactgt aaatatgtat
    19261 ttaaaataac aaattgacca tataaggagg aattgaaagt gttaaataaa ccattagagg
    19321 gagttaaggt tattgaccta acgtattttg tagcaggtcc agggacttct aaaatattag
    19381 ctgactgggg tgctgacgtt attaaggtag agccaagctt tggagaccca ggaagaaaga
    19441 caggggcaac aatgacaatg ccaatagatg attataataa tcctttttac agcacatata
    19501 attcaaataa aagaggtttg tctataaatc ttaagagtga aactggaatt gaaattatgg
    19561 ataagctttt aagcgaagca aacgtatttg tttcaagtta tagaacagga gcattaaaaa
    19621 gactaggtct tgattatgaa tcattaagta aaaagcatcc acaccttatc tggggtcaga
    19681 taaatggttt tggcgatttt ggacctgcta aggataatgc aggatttgat acagttgcct
    19741 tttgggcaag aagtggggct atgcttgata tagcagaaaa agatacaagt ccaataaatc
    19801 cacctatagc ctttggagat gcaacaactt cttgtagttt atctggagga atatgtgcag
    19861 ctttgtacca gcaagctaag actggaaaag gacaaaaagt aatggcatct ttatttgggc
    19921 aagcaatatg gaatgcatca tctttattag catctacaca gtttagtgat gagtatccaa
    19981 aaactagaaa aaatgctatt tcaccagtaa taaattctta tcgttgtaag gatggaaagt
    20041 ggatattctt aagtatttta gagcatgaaa gatattttga ggcactttgt agattatttg
    20101 gaagagaaga cttaataaaa gaagagaaat ttgcatcttc agtagaaagt aagaaaaatg
    20161 ctacagaact tattaatatt ttagatggtg aatttgcaaa gtttactcaa aatgagatgg
    20221 ttgaaaaact tactgctgct gatatagctc atgaaaaaat tcaacatgtt aatgatgtag
    20281 tgactgatga acaggctatt gctaataact atatatatga acatacaagt aaagatggaa
    20341 ataagacaat gcttgcatct actccagtta aatttggaaa tattgaagtt aacatgactt
    20401 gtgatgctcc acttatagga gaacattcag atgagatatt gagagaactt ggatacagtg
    20461 attctgatat agagactcta attgaatctg gaattgtaac aatgaataaa gaagcatgtg
    20521 aaatatgtta ataaacatgt gaagtatgtt aataaatagg agggaatttt atggatttta
    20581 gattaacaga agcacaatta atgcttcaaa gagtagcaaa agaatttgca gagaatgaaa
    20641 tagcaccaat agctgctgaa acagataaaa caggtatttt tccaagggag ctttttagca
    20701 aaatggctaa aataggattt aatggaattg gaacacctgt agagtatagt ggttctggtg
    20761 gggcagatat agaaaaggta attgttgtta ctgagattgc caaaaaatgt gcagcatctg
    20821 cagcaatatt atcaatacac acaatatatg ctcaagctat tttgaaattt ggtactgagg
    20881 aacaaaagaa aaaatacctt ccaatgatgg ctgaaggtgg gtgtgtaggt gcttttgcct
    20941 taaccgaacc taatgctggt tcagatgctg cgagagctgc aacaactgca attattgatg
    21001 aagaaactga tgaatatgtt ttaaatggaa ctaagtgttt tatttctggt ggaggtcaag
    21061 cagaatcatt aataatattt gcattgacag acccatcaaa gggaataaag ggaatgtctg
    21121 ctatcattgt cgacaaaggt actccaggtt tttcaatagg aaaaattgaa gaaaaaatgg
    21181 gtattcatgg ttcagaaact gcagagttaa tatttgataa ctgtagagtt ccaaagtcta
    21241 acttattagg aaaagaaggt aaaggattta atatagctat gacttgttta gatggagcaa
    21301 gaattggagt tggagctcaa gctgtaggaa ttgctgaagg ggctttagaa gaaagtatca
    21361 aatattctaa agaaagagtc cagtttggca agccaatttc agctttgcaa ggtattcaat
    21421 ggtatatagc agatatggcg acaatggtgg aatcagcaaa attattagta tattatgctg
    21481 cagatttgaa agctagagga gaaaaacaca ctaaagaagc tgctatggca aaatacaatg
    21541 cgtcacgtac tgcaagagag gttacaaatt tagcccttca aatccatggt ggatatggat
    21601 atatgaagga ttatccatta gagagaatgt acagagatgc caaaataaca gaaatttacg
    21661 aaggtacttc agaaatacac aaagttgtta tttcaagagc agtactagga taggaggaaa
    21721 agaatgaata tagttgtttg cttaaagcaa gttccagata ctaatgaagt taaaataaat
    21781 aaagagacag gtactctaat aagagatggt gtaccaagta taatcaatcc agatgataga
    21841 aatgctttag aagaagctct aaaaatgaaa gatgaactag gagcagtgat taaggttata
    21901 agcatgggac ctcctcaagc taaaagtgct ttaaaagaag ctttggcaat gggagctgat
    21961 gaagcttatt taatctcaga tagagctttt ggtggttcag atacttgggc tacatctaca
    22021 attattgctg ctgctataga gaaggttgga aagtatgatg taatattctg cggaagacaa
    22081 gctatagatg gagatacagc tcaggttgga ccagaggttg cagaattttt agggatacca
    22141 caagttactt atgcgaaaga agtaaaggtt caagatgaca aattactagt aactcgttat
    22201 acagagacag gggattattt aatagaagca aagatgccag ttttattaac tgctataaaa
    22261 gagttaaaca atccaagata tccaagtgtc aagggaatct tagaagctta taataatgga
    22321 gatgcaaaga ttactgtatt aacacttgca gatttagatg ttgatacaac tcaaattgga
    22381 ttaaagggtt cacctacaaa cgtttataag tcttttgtac cagttaaaga caagcataat
    22441 gaaataatag aaggtataaa taaaaaagaa aaagctgaga aactaataga aatactattc
    22501 gatttgaaac tagtatagga gtgttaagat gatgagagca aaagttaatc aaggtataaa
    22561 tttaaatgat tataatggtg tttgggtaat aggagagcaa agggaaggta aaattaatcc
    22621 tgttacgata gaacttattg gtgaaggaag aaagcttgct gaccaattag gaaaagagct
    22681 tgcagttgtg atagctggat atgaagtaga gaaagaagtg aaggaattac ttcactatag
    22741 tgttgataaa gtatattaca tcaatgaccc tcttcttaaa gatttcacta ctgatggata
    22801 tgcaatttca attgcaaatt taatcgaaag aaaaaagcca gaggttgtat tggttggtgc
    22861 tacttctata ggaagagata tagcgcctag aattgcaggt aaggttggaa caggtctaac
    22921 tgctgactgt acaaaacttg aaatagattc aacagataat aagttattac aaacaagacc
    22981 agcatttggt ggaaatttaa tggccactat tgtttgtcca aaaaatagac cacagatgtc
    23041 aacagttcgt ccaggagtta tggcaaaagc tgtaagaaac gaatcagaga ctggaatttt
    23101 agaagttgtt actccagaac ttactgaaaa aatgattaga actagattag tagagatact
    23161 tccacaagaa aagaaatctg taaatctaac tgatgctaga ataatagtat cagggggaag
    23221 aggattaaaa agagcagaag gatttgagct tataaaagaa ttggctgata aattgggggc
    23281 agagattggt gcttcaagag cagcagtaga ttcagggtgg atagaacatt ctcatcaagt
    23341 gggacaaaca ggaactactg ttagaccaga actatacatt gcatgtggaa tatctggagc
    23401 aatacaacat ttagcaggta tgagtgattc taaatatata gttgctataa ataaagatgc
    23461 aaaagcccct atttttagta tatgtgacta tggaatagta ggagatttat atgaaattat
    23521 acctgaaatg atagaatcat taaataggta acttttagaa aacattgaat atgtagaatg
    23581 ataagtctta taatattgta ttgtaagact tattattttt gctgaaggtt atagtgggga
    23641 gatgaaacaa tgaaagagca gtggtataag gatatatttg caagagtatt atctatgact
    23701 gatgatggtt ttattgttgt aaatacaagt ggagtaataa tagatattaa tgataaatat
    23761 tgtgactttt taggaaaaga aagaaaagat ataataggac aaaatataca aagtattata
    23821 ccaaatacaa aaatgctaga tgttatgaaa aataagtatt gtgaagaagg agctatacat
    23881 cattattcag gtggaaatac aaaagaaaaa agtgtaatag taagtaggtc ttatgtggaa
    23941 aatgacaatg gagaagtagt tgcaggagta gctcaagtta aatttagatt gcaatcattt
    24001 gatgtagcta aaaagttaat gtcagaatat atggagctcc aatattataa agagcagttt
    24061 aaggataact gtggttttga caagctcata ggtgaaaata gagacttcat agaacttaag
    24121 aaaacaggtg tgaaagcttc taaaacaaac tttccagtac ttttaacggg tgaaacaggc
    24181 acaggtaaag aagtttttgc tagagcaatt cacaataata gcagtaggtc agataaacct
    24241 atggttagta taaattgcgc tgcaatacca gaagaattat tagagtcaga gctatttggc
    24301 tatgacgaag gagcttttac aggagcaaaa aagggtggta aaaaaggtaa atttttagtt
    24361 gcgaataatg gtacaatctt tttagacgag ataggtgaca tgcctttgac catgcaagca
    24421 aaacttttaa gagttcttca ggaaagtgag atagaaccag tgggaggtct taaaactata
    24481 aagatagatg taagagtaat ctctgccaca agaaagaatt taagtaaaat ggttgaagag
    24541 ggattattta gagaagacct atactataga ttaaatgtaa taaacattca tatgatggaa
    24601 ttgaaggaca ggcaagatga tattttattg ctagcaaatt atatattaaa caaattaaat
    24661 gttgaataca aggaattgaa ggttttaagt gataaggtta aaaattgttt tattaactat
    24721 acttggccgg gaaatataag agaactacaa aatgtaataa aaagtgccta tgctgtaagt
    24781 gatgatatgg tcattatgat gtgtgacctt ccatctaaga tggataatat cagcagagta
    24841 gctcaatgta atgtggatag caattgttca attcatgaaa tggttgagaa ttatgaaaag
    24901 agcttaatta ttgatgtgtt aaggaagtat aattggaaat gttctaaggc agcagaggtt
    24961 atgggaatac acaagagtct tttatataag aaaataaaaa agtatgaaat tgaattaaat
    25021 aattaagata acttgaatta aggcaatgct aaaaaagcgc ccttattcaa agcgaactgt
    25081 ataaactgtt ttatgcagtt aaaacgtgta aaagtagatg tgaagtacta atgtcaatca
    25141 ttagtacttt tttattatat ttataattac tatctatatt tcagtatctt ttgatatcta
    25201 agattattat gtttaattta gtatataaca aaaccctctt agttatggac agttttttat
    25261 attttaactg tctactaaga ggggatagtt tagtttaaat ttagagtaaa ttttatctag
    25321 catttataaa aaatattttg aatagctttt ttgttattta gtcataattt tctacttctt
    25381 tatcaagttc tttgccacaa gaatcacact tatatatagc attgtatccg taatcatatt
    25441 catcaactat tttcttttgt ctaaatacac caccacactc acataggaaa ccaattttta
    25501 taagtgtaac gataaattgt gattttataa attttatatc attgcattta tcgttagtgt
    25561 aaaatgtata aatataagag ttatcgcact catctcttaa ttcaaatctt tcaatatatg
    25621 tgttattttt taattcctca aattcttctt tagttaaata tgatttttgt tgcaattcat
    25681 gtaaacgctt aatttggtcc attatttata tcctcccaat aattttagta ttttaagctt
    25741 agataaggaa tctaagtttt attaaattta tcccaaggaa ttatttaaat catatttagt
    25801 tttattaatt acaacatata taaattacac gaaaataaaa ctaattgtaa aaataatatc
    25861 ctgtgaaaac ctaaactact aaccccttac taacccgaaa actaaaaaaa gaaaatatat
    25921 ccaaatataa gtgatatata aataaagatg tttcatataa atttaacttt aaatattctg
    25981 acaataatat a
//
LOCUS       DAEPXW010000054        25872 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.055, whole genome shotgun sequence.
ACCESSION   DAEPXW010000054 DAEPXW010000000
VERSION     DAEPXW010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25872
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.055"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            177..554
                     /locus_tag="KRM55_002244"
     CDS             177..554
                     /locus_tag="KRM55_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1594484.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            547..1695
                     /locus_tag="KRM55_002245"
     CDS             547..1695
                     /locus_tag="KRM55_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBH1594485.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLTDCSLKDKKEYALALIKSIKLSKNYNSGILTTEFNKTNLE
                     KRLESIVKKKGRSGILIAILVIMTSITSFIEVDAQIKINNSINEINNNINDFILNKST
                     DKHQTFYYKDAPSKIRKFYEDNCKLKGTTPKDYDTIIINTKDFNELMK"
     gene            1712..2311
                     /locus_tag="KRM55_002246"
     CDS             1712..2311
                     /locus_tag="KRM55_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBH1594486.1"
                     /translation="MLKKSKKTLAIMCCLMLTFTSVAFADASKGEGVSKEAVSEKNTY
                     SFNISGYVYTYENAPQKIRDEHKQNCEDVNIAPKPDDKIFVPTSANLMNDDDKAVYTN
                     YAVAYKPDEKTITVIGGGEFITISTTKVIRKGDTGKEVTVAQIMLSKLGYNTSPDGIF
                     GSKTYNAVVSVQKKYGLSADGVIGPATWDKLGRLTDSSF"
     gene            2449..3562
                     /locus_tag="KRM55_002247"
                     /pseudo
     CDS             2449..3562
                     /locus_tag="KRM55_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            complement(3832..4854)
                     /locus_tag="KRM55_002248"
     CDS             complement(3832..4854)
                     /locus_tag="KRM55_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH1594487.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPAIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(5183..5365)
                     /locus_tag="KRM55_002249"
     CDS             complement(5183..5365)
                     /locus_tag="KRM55_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594488.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            5678..6097
                     /locus_tag="KRM55_002250"
     CDS             5678..6097
                     /locus_tag="KRM55_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBH1594489.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            6228..8069
                     /locus_tag="KRM55_002251"
     CDS             6228..8069
                     /locus_tag="KRM55_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1594490.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            8096..9982
                     /locus_tag="KRM55_002252"
     CDS             8096..9982
                     /locus_tag="KRM55_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1594491.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNGTRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            9990..11990
                     /locus_tag="KRM55_002253"
     CDS             9990..11990
                     /locus_tag="KRM55_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1594492.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            12252..13511
                     /locus_tag="KRM55_002254"
     CDS             12252..13511
                     /locus_tag="KRM55_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1594493.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLILVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            13572..15359
                     /gene="iorA"
                     /locus_tag="KRM55_002255"
     CDS             13572..15359
                     /gene="iorA"
                     /locus_tag="KRM55_002255"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBH1594494.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVEHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            15361..15936
                     /locus_tag="KRM55_002256"
     CDS             15361..15936
                     /locus_tag="KRM55_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBH1594495.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            15989..17059
                     /gene="buk"
                     /locus_tag="KRM55_002257"
     CDS             15989..17059
                     /gene="buk"
                     /locus_tag="KRM55_002257"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH1594496.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQCSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            17277..17978
                     /locus_tag="KRM55_002258"
     CDS             17277..17978
                     /locus_tag="KRM55_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594497.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            18038..18544
                     /locus_tag="KRM55_002259"
     CDS             18038..18544
                     /locus_tag="KRM55_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBH1594498.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            18719..19741
                     /locus_tag="KRM55_002260"
     CDS             18719..19741
                     /locus_tag="KRM55_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1594499.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(19888..20196)
                     /locus_tag="KRM55_002261"
     CDS             complement(19888..20196)
                     /locus_tag="KRM55_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH1594500.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(20256..20684)
                     /locus_tag="KRM55_002262"
     CDS             complement(20256..20684)
                     /locus_tag="KRM55_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594501.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(20907..22364)
                     /locus_tag="KRM55_002263"
     CDS             complement(20907..22364)
                     /locus_tag="KRM55_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH1594502.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            22782..23696
                     /gene="nadA"
                     /locus_tag="KRM55_002264"
     CDS             22782..23696
                     /gene="nadA"
                     /locus_tag="KRM55_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBH1594503.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            23709..25010
                     /locus_tag="KRM55_002265"
     CDS             23709..25010
                     /locus_tag="KRM55_002265"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBH1594504.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            24991..25827
                     /gene="nadC"
                     /locus_tag="KRM55_002266"
     CDS             24991..25827
                     /gene="nadC"
                     /locus_tag="KRM55_002266"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBH1594505.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
BASE COUNT        10272 a         2746 c         4374 g         8480 t
ORIGIN      
        1 atatgtaaaa agtaaaatat ttaaatagat atattttaaa atctaacttt taatattgta
       61 aaaaaattag aaatttaaca aaaagtacaa aaattcacat ttttttcata aagtgtttga
      121 ctaaaaaatt cacatgttgt agaattaagg tagcaggagt tttgagggag gtgtaaataa
      181 tgataagaaa aataccacaa gcagaactaa aagtaatgaa attcatttgg aaagtagatg
      241 ttacagtgac atcaaaagat gttattgaag ctatggaaca aaaatatggc tggaaacaaa
      301 ccaccacact gacactttta tctaggctgg taaaaagagg attcttagat gctcaaaaaa
      361 tagacagata tacacattac acaataagag taaaacacaa agattattta agttttgaga
      421 caaaggattt cctaagtaat atacatgatg actctttgag aagtttaatt tcagcattac
      481 atgatgatga aaatataggt aaagataagc tagattttct agaaagttat tttgataatt
      541 taaaggatga ataattatat gctatatgtt tttgaaaatc ttataaagac aactattgta
      601 tgtagtcttg gtatttgtct attattattt ttgaaaagat atttatttaa gaagtttagt
      661 aagagattca attattatat ttggttgata atagtcttta gaatgttact ttttctattt
      721 aattatacaa tagtatatga agtaaaagaa cccaaagaaa atgcattagg aaataatatt
      781 acacaaattg atatttctac agataataat cttatgctgt atgtagctta tttatggtta
      841 tttgtaacta tagtcattgc agtttataca tttataaagt atacaagatt taaaaatcta
      901 gttgttgatg tatcttatga tattgaagat aatgatataa actgtatcta caaaaacttg
      961 ttaaaagaat taaatataaa aaagaaaatt gaattaagag gttctgatga attgataagt
     1021 ccagcaggca tgggattatt taaatcttac atattcttac cagactatcc ttatagtaaa
     1081 gatgaactaa cttggatttt gaaacatgaa ttaatgcatt ttaaaaataa agatatttta
     1141 ataaagtttt tagttttgtc tgttagaata atatattggt ttaatccact tgtatatgta
     1201 atgagcaata aagtaaatct agattgtgaa ttatgttgtg atgaaagtgt tttgactgat
     1261 tgttctttaa aagataagaa ggagtatgca ttagcactta taaagtcaat taaacttagt
     1321 aagaattata atagtggtat tttaacaact gaatttaata aaacaaattt agaaaagaga
     1381 cttgagagta ttgttaagaa gaaaggtaga agtggaatat taattgctat attagtaatt
     1441 atgacttcta taacatcttt tattgaagtt gatgctcaga ttaaaattaa taatagtatc
     1501 aatgaaataa ataacaatat taatgacttt atactgaata agtcaactga taaacatcaa
     1561 actttttatt ataaagatgc accaagtaaa attagaaaat tttatgaaga taactgtaaa
     1621 ttgaaaggta caacacctaa agattatgat acaataataa ttaatactaa agatttcaat
     1681 gaattaatga aataattata aggaggattt tatgttaaaa aaatcaaaaa agacattagc
     1741 tattatgtgt tgcttaatgc ttacttttac aagtgtagca tttgctgacg caagtaaagg
     1801 agaaggagtg agtaaagaag ctgtttcaga gaaaaacaca tattctttta atatttctgg
     1861 gtatgtatat acatatgaaa atgctccaca aaaaataaga gatgaacata aacagaattg
     1921 tgaagatgta aatatcgcac ctaagccaga tgataaaatc tttgttccaa catcagctaa
     1981 tctaatgaat gatgatgata aagctgttta tacaaattat gctgttgctt ataaacctga
     2041 tgagaaaacc ataacagtta taggtggtgg tgaatttata actataagta caacaaaagt
     2101 tatacgtaag ggtgatactg gaaaagaagt tacagttgcg caaattatgc tatctaaact
     2161 aggttacaat acaagtccag atggtatttt tggaagtaag acatataatg cggtcgtaag
     2221 tgtacaaaaa aaatatggtt tatctgcaga tggagtgatt ggtccagcta cttgggataa
     2281 attgggtaga ttaactgatt ctagttttta ataggattaa aatctaatat taaatagtgt
     2341 tccaatgtga tttcttaaga gcttttaaaa taaagtgtgt attcttctaa aaagtgatga
     2401 taattaaaat ataaaatatc actatacaaa ggaaggtaca cactttttat gtttaacaaa
     2461 aacgaaatat taaaaaactt attgaagaat atgatgtcaa aacaactaca aatattcaag
     2521 acatactaaa ggttttattt gcaagtacaa ttcgtcaaat gttggaaacg gagtttgatg
     2581 actatttagg ttatgataat aagaataaaa ctgctaaaaa ctctagaaat agatatagaa
     2641 ataaaaatgt tgaattagat tttggagaaa taactttaaa tattccaaga gactgaaatt
     2701 gagattttga accaaatgta attagaaact atgaaagtga tatatctgaa atagagaacc
     2761 aagtgattgg aatatactca aaaaaggtat gtctactcaa gatatatcaa ggcacattaa
     2821 aagtatttat ggaatggaca tatataatta attaatagct aaagctactg atatagttat
     2881 atctttagct catgaatagc aaagtagact tcctgatatg atttattcaa ttgtatttat
     2941 gatactatat agtataaagt tataagttaa aatagaataa ataaaaaagc agcatctata
     3001 gctacaggta ttaacttaaa agggataaat gaggttttat gaaccatggg ttggagaaat
     3061 gaaagtttaa aatgttgcct aaaggtactt acagatatta gaaacagagg agttaaagat
     3121 atattaatag cttctgtaga tggattagtt agattttctg atgcaattaa agcagtattt
     3181 cctgatactg aaatacaaag atgtgttgtg catcaaatca gaaatacttt aaattatgta
     3241 tcatataaaa atagaaaaaa atttgcaaga aatttaaaga aaatatagga ttcaattata
     3301 gaagaataag cgttaagtaa gctattgctc ttaaaagaaa aaaggggcaa tcaatatgcg
     3361 atagcattaa gaagttggtg aatcagttga aatttacaat agattattaa gaaaagttac
     3421 taaatcgaag tctatttttc cttcagatga ttctttgcac aaatcattat acttagcaac
     3481 tatatatatt tctgaaaaat ggactcaaat tttatcttat ttaagtattt attttaaaga
     3541 aagaaattta aatctaaatt aataagaaat atttcaaaaa atcaagaatt tttcttaaag
     3601 tgataataat ttttgcaaaa atggaaaaaa tatcaaaata aggctatgat ttttaaagct
     3661 atagccttat cagtaaaaat ttaattatca tttaaaaaat aaatttttat ttaaagaata
     3721 gacataaata tttccagact ctctcaatat gatttattaa acactaaatg agatactatt
     3781 ttgtatacgt taaaggatat attatttaaa tataaatgtt ataaaactat tttacaataa
     3841 attccatata actctaccat ctatatcctt aacattttgg caaccagtca aaatcatagt
     3901 ctcacataac tcattcctaa ccttctctat aaaaaactcc acaccatcaa gaccaccgcc
     3961 aaaagaagca gtaacaaaag gtcttcccat caaaacagca tcagcaccca atccaagcat
     4021 cttaactaca tcaacaccag tcctaacgcc accatcaaca agtattgtta tctttccctt
     4081 tacagactta gctatagctg gaagtacctc acaagtacca ggagtataat caagtactct
     4141 tccaccatga tttgaaacaa taatggcact agcaccagac tctacagcca tcaaagcatc
     4201 atctacagtc ataattcctt ttataataaa aggtaatcta gtggattcaa ccaattctct
     4261 aatctcatca attgttttag gagaaaaagg attttcttga aattgattat taataagtcc
     4321 acaagcatca aggtctacac caactgcaaa agcacctgct tcttcagaca atctaatttt
     4381 ttctattatc tttgaattat tccaaggctt tataaataca attccatttc ctctattatc
     4441 cttcaacaca tctaaattat ccagtaaaaa agtatctaca ttagtatcgc caaccatagc
     4501 ataaattcca gaattagaac aacctctaac aacaggctct atgtattctt tttcggaaac
     4561 tttaccaccc atgttcaata tagtacctga tacaggtgca gcgaatatag gagaactcat
     4621 ttttctacca aataattcta tggatgtatc tggctttgaa acattatgta tgactctcat
     4681 atttatcttt attttttcta gactttttct attttcaatg aaagacgaac cacttccttt
     4741 accacccata ccaggaacat ctccagcaca agctaatcca ttacaaattt tacatacttt
     4801 acatgttcca ttaaagttct ctctagctga ttttagtaag tcattgtaat tcatacaaaa
     4861 tctctccttt ttataatatt aaaattgagt attactatat tgaaaatatc ttaattgtaa
     4921 atatagggat gttattatga tgagctaaac tagataatac atattagata ttttttattg
     4981 ttgtagatag ttaaattata tcatattaga tagtcaaatt ttgaaaaaaa ctaacttatt
     5041 taagtataca ttttgaaaaa attaaaaaag ctatatatag atttttaaag aaatctatat
     5101 atagctttta agtttatgtc aatctttttt gttaatgaat aaataatata gaatacaata
     5161 tacaaaaaag tttcttgaaa tgctaagata atccccattt acaaagcagc atcattatac
     5221 tgtgtaaatt tgaatcaaca atgttttcac catatttcat cataaaatcc tctaattgtg
     5281 tgtcaataaa tgaataatat ccacttatac tatcgatgta tgcagtcatt aagtgtatac
     5341 attcatcact tttatcttta tacatatata tctcccccta tatacaatat ataaatttag
     5401 ataccaaatc gtatcatatt aaatagttaa gtgtgtaaca tctatgcagt tatatattta
     5461 tatcattata ttaataacta aagtgagttt tgacaataga ttttgggaaa ctggatgttc
     5521 aaagtgcaaa cttggatttt aaaatcatta attaagatag cgcataggaa tatatgtata
     5581 cataacttaa ttataaagat tataaacaat tacttttatt aactttattt aaatggtaga
     5641 ataacttgga gattaataat tataaggagg atataatatg agtttatata agtttatata
     5701 tgatgataag gaatatttat taaaagagga gaactgtagt gctttaataa atgatgaaga
     5761 aaatccagtt caaggagtaa gtatttcaaa aataattgat atacttaatg aagcagaaga
     5821 agttgatttt gatgtagaat attatcaaga agcatgtcca ttatgtttag aaggagtaaa
     5881 agaaaagaaa aaattctttc cttttttaga atatcacttt tatattttca gtaaagatgg
     5941 agaatatgta ataagcaata tatctgttga ttataaagga ctatctttta ataaactatc
     6001 aagggcaaat aaagttgata atagttatat tgtaagtgtg ataatttgcg aaaattgtca
     6061 ggattatata gttcagatag aaaattgtat agtttagtgt aaagtatgtc ttaatttaag
     6121 agaaatttct aaattgagac atcaactttt ttcaaaaata gtatggaaaa ttactaaatt
     6181 tatgagataa tgtaagtcgg aggtgagtta caatatatag taaatatttg gaagagatag
     6241 atgatacaat tttagattca atgtttaaac taaccttgaa tgaaagatta ttgactaata
     6301 acgattttat tgaaaataaa attgatgtag taaagaattt aattgattgc tataaaactg
     6361 aacaaaatag tttaatgtta ttaaaatcaa attttttgct agctttatta tatggtattc
     6421 aagggtttag tgaaaaaatg aaagagtata ttttgatttc ctgtaaatat attgataaat
     6481 gcttacccaa agattataaa tttttagcac gattttattc acaaatagct attttaagtt
     6541 taaaaaatga agatgtaaat aaggcaaatt tatatatgga taaatttaat cttatttgtg
     6601 atgaaaataa ttttctaatt gaagaaatta tttttaaatc acaacttatt tacattaagg
     6661 caagtaagtg tatagaatct tctgtaataa ttaaagaaat agaaacgttg tatataaaga
     6721 taaaagaaat taacgatttt aattgtaaaa aaatatattt ttttattatt ggtaaaatat
     6781 attttttgtt tttggatgat gctctaattg ctaaggtaaa ttttttaaaa gcaagaaaat
     6841 atgcagattt actaaaggat atgcaagtat cttcactatg taatataaag ataggtgagt
     6901 gtgaatgttc gtttgaaaat tatgaatgtt ccatggaata tttcaatgaa gtaataagca
     6961 ataaaaagta tagaaatgta aatataattc aaaaatatag agcatcaaac aacataacta
     7021 aaatattaat aaagactaga aattatcctg tcgcaataaa taatttagca aaatctgaag
     7081 tatatctaga aaaaattaaa aatcatagct taaaagaagt agagaagttt gatttattta
     7141 taagtttagc catgtattat gcaaaaagta atgaaaaatc ttttgaacaa tcaatatgct
     7201 atttagatag agctaaaaac atattaaata tgataaaaaa tatagaagaa tatataatat
     7261 atgatttaga aataatttat caccaggcaa agatatatta tatctttgga tattatgaca
     7321 atgccttaaa cacaaataaa aaactccttg aaaaatctaa aaatgctaaa aattataatt
     7381 atgtgaagtt agcatacaag agtatatatt tgtgttttga aaagattcaa aattatgaaa
     7441 tgagtatgaa atactttaaa atgtattatg agttaaaaat gatgtatata aaagctcgaa
     7501 atagaaatta tatagattcc ttaaattata gacatgagta tatagaaaaa gaaataaata
     7561 acatgagaaa agtaaaactt gatttagata aaaaaaagta tgttgaccat ttgacaagtg
     7621 catataatag aacttttttg aacgattttt tagaaaaaca agaagttagt gaatattgca
     7681 cagcatttat gatagatgta gattacttta aagaatacaa tgatacttat ggacactata
     7741 atggagatat tgctcttaaa aatataacta taataataaa aaaatatcta aaaaaagaca
     7801 tgcttatgat aaggtatggt ggagaagaat ttctgatatt atctgtatgt aaagattata
     7861 aaaaaagtaa aatatttgga agaaaattat gtaggattgt aaagaaattt ttaaacaata
     7921 atttgacagt tagtattggc attgatacat gtaaaaatag tagtatagat ataaaagaaa
     7981 taattgaaaa tgctgataaa gctttatata aagcaaagga aagtggtaga aatagatgtt
     8041 tgcattatca tgattttaag aatttttaac tgttgaaata ggattggtga tttacttgaa
     8101 aaggagttta atagaagatt taaagagaaa tataaacaag atagaatacg atatgttgac
     8161 taaattctat ctaaatttga cagatttaaa ctacatcttg gattatcaca aagacctttt
     8221 aaatacaaaa ttagaagata atagtagagt ctatacttta tatttaatta gtcttataaa
     8281 ctatataaaa aaagatagag aagcatcata caactatttg atagagtcat taaagtatat
     8341 taaaaaattg tcattaaaag atgattcaga tataatatct aaaatttata tttatcttac
     8401 tttatcagct atttctataa gaaaatatga taaggtaaat aatttttatt tctcagcaaa
     8461 aaaaattata agacaaaatc atttaaatga gttgttggta ttgttaaata tgagtttatg
     8521 tgtagaaata agtgctttat atcagaccaa aacggatgta atagctttag tagaagaagt
     8581 gtcttttttt aaaactttaa aaaataaagc tcttgtaagt agggcaaatt atatatttgg
     8641 gagagtttat ctatatttat ttaataactt tataaaaagt atggaatact taattgaatg
     8701 tctaaaattg gctcaagaaa ataatttata ctctatagag gctttttgta aatgtataat
     8761 aagtttgtgt tatttagaga gtggaaataa tgtagaagct ataaaataca taaataatgt
     8821 attagatgtt gcacacagta ataactcaat atcagtaact gaaagagtgt ctataaagat
     8881 agaccttata tgggcatatt taaaagaaga tatgaataaa gaagcagaag ttattttatt
     8941 aaagactata aaattaatga aagttgttga aggtgtatat aaggattatt tatattcatt
     9001 tatattttta tattcagctg aaattgagtt aaagaaagat aattgtagtt ttgaaaaggt
     9061 aaacacctat ttaattttat caaaaaatat atataaaagt tttggagatg tttttatata
     9121 taattctaaa ctagattaca tatataagtt gtatggagat ttatatataa aatttggtaa
     9181 tatagatgaa ggtataagtt gttatataaa aggtttaaat ttagttaaaa agagttcatt
     9241 gaatcttaga aaaatatcta tattttatgg gctaatagca aatggatatg agctaaaaaa
     9301 agattttaaa ctggcaatag aatattataa aagtatggat tggtattctg ataggtggga
     9361 aaaaaataat tcctataaaa catctcaagc aattcacaaa caatatgaac tcagacaaaa
     9421 acaagagagt ttaagattac tagtggatga taataagaaa ttagaaaatg atattttaaa
     9481 agatggactt actaaactat ataatagaag atatttggaa cagcagttgg atttatttaa
     9541 tggaaccaga gacaaaaata tggtcgcaat actggtcgat atagattgtt ttaaaagtta
     9601 taatgataat tatggtcatc tagcaggaga taaagttata gttaaggtaa ctgatattat
     9661 aagaagtgta tttatagata ttaccgaaca cataatcaga tatgggggag aagaaatttt
     9721 aatattagta gattctatag aatcaatcgg tgttgaagag attgataata tagaattata
     9781 tattaaaaga gttttcaaac ttcttgaatt tgagggtatt gaacatatat attctaaaat
     9841 aaaaaactat ataactataa gtgctggagt aagtataaaa aggtgtcgta gtagaaaaga
     9901 tgttgaaata ttaattgaag atgcagataa gaacctatat aaatcaaaaa aagcaggtag
     9961 aaatcaatac attataattt aaaattgagg tgattttgtt gcgaaaaaaa ataggaatta
    10021 tagcctctga tattgaatta aaagaaagaa tagaagaatt atatagagaa gatgtagaaa
    10081 atggaactat aataatcgac atacttaacc tagacttaat ggaaaatcaa ggtcgtatac
    10141 ttgttgaaaa aggtgcccaa gctataattg gtagaggtgg aggttatagc ttagtaatag
    10201 atacagtaaa tgtacctgtt ataccaatga atatgaagtc aactgacctt ttaagagcaa
    10261 tagaaatagc aaagaaatat tctaaaaaag tagtattgat tcttggagac aatgaagttt
    10321 cttttgacta tgttggctgg agaaatgtca taagtactga aataactgaa gaatggtttg
    10381 aatctaagta tgagataaga agtaaagttg taaaatatat agaccaaaaa gatgaagttg
    10441 taatcgtagg aggaggtttg gcatgttctt ttgcaaggca atatggaatt gatagtgtat
    10501 ttgcaactgc tagtgatgaa tctataagag aagctgtaga atattgtaaa aaattattag
    10561 atacattagg tgaagaaaag tttaataatg aagtgttacg aaatatactt gatggtataa
    10621 aagatggagt aattgctata gatagtaatg gcagtataat tttgtacaat gaaagtgcaa
    10681 aaaacatgct taaagtagag agaaaatgtg cacttaataa atacatctta gatgtatttc
    10741 ctaaaatgga gtggatgtta gattgtttac atgaaaaaga ggacgtagaa gatagaaaga
    10801 taagaaatat aaataatcta attgttaata ctaggacaac attgataaaa gttgataata
    10861 gtacttatgg agttttagga ataatacaag atataaccaa gctacaaaac ttagaaagaa
    10921 aaataagatt tgacttgaat caaaaaggtc tctatgctag atatactttt gatgattttt
    10981 tatttaaaga taaattaact aaagaattta ttgaagaagc taaaaaaatt ggaaaaagtg
    11041 attatacaac tttactttat ggagaaagtg ggtctggtaa agaaattata gctcatagta
    11101 tacacaacat aagtaaaaga aaagataggc cttttgttgc tataaattgt gctactatag
    11161 cagaaaattt acttgaaagt gaactttttg gctatgaaga aggtgcattt actggtgcta
    11221 gaaagggtgg aaaaagaggg ctatttgaac ttgctcatgg agggactctt tttttagatg
    11281 aaataaatag tctatccttt aatattcaga caaaactatt aagagtaata gaggaacgtc
    11341 aaataatgag aattggttct gattatataa tacctctgga tataaggatt atagcagcaa
    11401 cgaacgaatc tttaaccgaa aaaatagtta tgggtacatt tagagcagac ttattttata
    11461 gattgagtag tttagagata aatatacctc ctttaagaga cagaagagaa gatataatac
    11521 ctttgtttaa caattttgta aatgaagtat taaaggatga tggtctcaat ggaataaaca
    11581 gtatagatga aaattttgtt ttgactaaag atgaaatgga taagctatat aattatagct
    11641 ggcctggaaa tgtaagagag ttaaagacaa tagctcaaaa atatgttgtg acaggtaaaa
    11701 ttaaattgag acaagataga gattttaaaa ctaaaaaatt acttcctaac tctgaagtag
    11761 acaaatttaa ttctgaaacg acagcaagtg tagaagtcca agatgaatct ataaatataa
    11821 gtaagataaa tgatggtaag ataagtatag atataaaaga agtaaataag tatgttgaag
    11881 aaaaaataat aagtatgctt tttgctcaag gactttctaa aaatgaagtt gcacaagttc
    11941 ttggaataag caggacatct ttatggaaga aatacaataa aaatatttaa atataattac
    12001 atataaatta ttttgaagta atgttaattt tttaaaacaa gtgttaagaa aaattaacat
    12061 tacttttttg caaattttta tttttttaga caggcatata tatttataag aaaaatagtt
    12121 aaaacactta atttaataat gaaaaaaata ataattctaa acaaaatcaa ttttacataa
    12181 agtgggattt attggcatag taattgctta atatataatg taagagtaaa tacaatttta
    12241 ggggtgatgg tatgagtcaa agtatggttg gtaagcatgc aatgtggcca aaagaaaatg
    12301 atgttatatt tagcatatct ggcagagctc aagcagcaga gaaggctttt ggtatggata
    12361 atgtaataaa tgcaacaata ggcgctctaa tggatgattc aggaaaatta ataacaatga
    12421 aaactgtata tgaagaatat aaagcattag ataactgtga gataggtgca tatgcagctc
    12481 ttgaaggtca accagattac ttagaagcag ttaaaaaagt atttttcaga gattacttac
    12541 cagaaggaca tataagagta ttagcttcac caggaggaag tggtgcaata aaattagctg
    12601 tatggaacta tactaatgaa ggagatgagg tattaacatc tgattggttc tggagtccat
    12661 atgtaagtat agctgaagag gctaatagaa aagtagttaa ttaccaactt tttgatgaaa
    12721 atagaaggtt taattttgag tcgtttaaag aaaaatttgt aaatatagca gaaaaacaag
    12781 gtagagtctt tacaattata aacacaccag cgcataatcc aactggatat agtgttgcag
    12841 atgatgagtg ggataaaata ttagacttat caaaagaagt cgcaaaagat aaagacaaaa
    12901 agataatatt tttcgtagat tcagcatata ttgactttgc aggtgatgat gatgtatgta
    12961 gaaagttttt taagaaattt tctaatttgc ctgaaaacgt tctcatattg gttggattca
    13021 gtatgtcaaa aggatttaca gcttatggta tgagaatggg ggctataatt tgtatatctt
    13081 caagtgaaga tgtagctgaa gagttccatt actcatgtgt tcattcatgt agagcaaatt
    13141 ggtcaaattg taatagaagt gccatggcag tattatctaa cattgtaaat gaccctaaaa
    13201 aattcaaaga atatgaggat gaaaaagaaa tatacaaaaa catgcttact agaagagcag
    13261 atgtatttgt aaaagaagct gaaagagtag gattagaaat tcttccatat atagcaggtt
    13321 tctttgtaag tataccatgt gataatccaa aagaagtatg tgaagaattg actaaacata
    13381 atttatttgc agttccatta aaaatgggct taagatttgc agtttgtgca gtttctgaag
    13441 ataaatgtaa gaaagcacca agtattataa aagaagcact tgaaagttta gaagtaaaaa
    13501 taaataatta atttcattga acaaattggg tggactatga atttaataat tgtagatgga
    13561 gggaatttta tatgaaacaa ttgatgacag gtaatgaagc aattgcacgt ggagcctatg
    13621 aggctggtgt taaatatgca tctgcatatc cagggactcc aagtacagaa atattagaaa
    13681 atatagcaac atataaagat gcaatagttg cagagtgggc tccaaacgaa aaggtagcac
    13741 ttgaggctgc tatagggggt tcaattgcag gagcaagaac aatggcttct atgaaacatg
    13801 ttggtttgaa tgttgcagct gatccaatat ttacttatgc atatacaggg gtaaatggtg
    13861 gtatggtact tattacagca gatgagccgg gaatgcattc atctcaaaat gagcaagaca
    13921 ataggatgta tgcaaaattt gcaaagatac ctttatttga accatcaact agtcaagaag
    13981 ctaaagatat gataaaagaa gcttttgaag ttagtgaaaa atacgataca ccagttttat
    14041 atagagttac aacaagactt tgtcattcaa aaggattagt ggagtgctat gatagagaag
    14101 aagttgaaat taaagagtat gttaaaaatg ctaagaaaat ggtaactgtt ccagcaaatg
    14161 ctcaaataag aaggggcgtt gttgaagaaa gaatggaaat ccttaaaaaa ttctcaaatg
    14221 aaactgattt aaactactat gaaataaatg atacaaaaat aggtgttata gcctctggta
    14281 tgtgttgtaa ttttgccaaa gaagtttttg gaaaaaatgc atcatatatg aaactaggat
    14341 ttacaaatcc actaccatat gaaaaaataa aagaatttgc agaaaaagtt gataaaatat
    14401 atgttataga agaaaatgac ccatttatag aagaacaaat aaaagcatat ggaatagatt
    14461 gtattggaaa agatgtaata ccaccatatg gagaaatgac accagatgtt ttaagaaaag
    14521 ctatatttgg aaaaacaaat gatactatag aatacaaatc tgaattagta acaccaagac
    14581 caccaagttt ctgtgcagga tgtccacata gaggattctt ctatgaactt ggaaagagaa
    14641 aaaatttaat agttggtgga gatataggtt gttacactct tggatttgct cctccatata
    14701 atggaataga ctatgttgtt tgtatgggtt ctgcttttgg aactgcacat ggagctcaaa
    14761 aagttcttaa tatgaaggat gataatgaaa aaagattggt aggtgtactt ggagactcaa
    14821 cattcttcca tacaggaata aatggacttt tagatgttgt ttacaataga ggtaattcta
    14881 tttcggttat attagataat agaataactg gaatgacagg tcaccaagaa aacccaggtt
    14941 caggatatac tttacaaggt gctaaaacta aagaagttga tatagaagga ttagttaaag
    15001 cttgtggaat agaacatgta agagttataa atcctaacaa tttaaaagaa gtaaatgaag
    15061 cactagattg ggctttagct atagaagatg aaccatcagt aataataaca agatggccat
    15121 gtgtacttaa aaaattctct aaagaagata tagaagaatt taataatcca tttaagacta
    15181 agtgtaaagt tgagcatgat aaatgtatag gatgtaaatt atgtttgaaa actggatgtc
    15241 cagctctatc atttgataaa gagaataagt tatcaaatat agatagaaat cagtgtgtag
    15301 gatgtggagt atgtgcacaa gtttgtccaa aacaagcaat agttaaggag gaaaaataat
    15361 atgactaaga gtatactttt ggtaggtgta ggaggtcaag gaactatact tgctagtaaa
    15421 ttattaacta tgggattgat ggaagctgga tatgatgtaa agatgagtga aatacatgga
    15481 atgagtcaaa gaggaggttc agtttcctca caagttagat atggagattg tgttcattct
    15541 ccagttatag aaattggtgg agcagatata ttagtatctt ttgaaaaaat ggaagcttta
    15601 agatggttca attatttaaa accagaagga aaagctttag taaataatca taggatagat
    15661 tctatgactg ttttaatcgg aggagctgaa tatcaagaaa gtgatataga tgcagagtta
    15721 agtagattaa atgcaaaagt tataaatgca gctgataaag ctgaagaact aggaaattca
    15781 aaaataatga atgttatttt attaggatgt ctagttaaat ctatgcaatt agagtctatt
    15841 gattgggaaa aaattataag tgaaaatgtt aaaccaaaat ttgttgaatt aaacataaaa
    15901 gctttccatg aaggtatgga aatggttagc aaatagttta taatagatat aaatagacta
    15961 tagaaattaa ggtgaaagga agaaaattat gacttacaga atattagcca taaatccagg
    16021 ttctacttct acaaaaatag cagtatatga tggagaagaa caaattcttg tgaagacgat
    16081 agaccatcca gctgaagaga ttgcaaaata taatactata caagaccagt ttgaaatgcg
    16141 taaggaagca gttttgaata ttcttaaaga aaatagtata gacttaaaat ctcttagtgc
    16201 aatagtagga agaggtggag ttttaccacc agtaaaatca ggagcatatt tagtaaatga
    16261 agaaatgatt gatgtactaa gacatagacc agtacttgaa cacgcttcca atttaggtgc
    16321 tgttgtggca catgcaatat cagaacctct tggaatcaac tcatatattt atgattctgt
    16381 tgcagtagat gagcttatag atgtagcgag aatatctgga ctttgtggaa tggatagatc
    16441 aagtgcaggg catgcattaa atactagagc aatggcttta aaatatgcta aggataaagg
    16501 aaaagattat aagagcttaa acttaatagt agctcacatt ggtggaggag taagtattta
    16561 tcttcatgaa aaaggaagaa tggttgatat gctatctgat gatgaaggac cattttctcc
    16621 agaaaggtca ggaagagtac ctgctacaaa attagtggct gcctgttatt caggtcaatg
    16681 ttcagaaaga gaaatgacta aaaagataag aggtaaaggt ggtatagttt catacctaaa
    16741 tactgtagat gctagagaag ttgaaaaaat gatagcagaa ggaaatgaag aagcaaaaat
    16801 tatttatgaa gcaatggctt atcagttagc aaaaggtatt ggagagttag caactgtagt
    16861 agatggaaag gtagatgcta taattataac aggtggaatt gcatattctg aaatgtttac
    16921 ttcaatggtt aaaaagaaag ttgagtttat agcaccagta gaaattatgg caggagaaaa
    16981 tgagttggaa tcacttgctt ttggaacttt aagagtacta aatggagaag aagaagctag
    17041 aatttatagt gaaaattaat aagaaaaact aaaaatgttt atatactaaa aaagtggtat
    17101 atccgttttt tatacacgaa agcttagagt ataggtgaaa atgtataaaa tttggattgc
    17161 cactttttat aattaaaatt ttatcttaac ctaataaata attctgtaaa atttcgtatt
    17221 tatatatata ttttattggt atttattgtt attattatta tgaggagtga tttttgatgg
    17281 gaaaaataag tttaaaaagt atgataagat tattttcagg tttttttata tttgcaattt
    17341 cttctgtgct tatgattaat gcacatgtag gtcttatgcc ttgggatgta cttcaccaag
    17401 gtttatctat aaagctaggc ataactatag gtcaggcttc tataatggta ggagttgtaa
    17461 ttgttatatt ggatgcagtt tttggtgaaa atataggatg gggtacttta ctcaacatga
    17521 catttatagg aatttttatt gatttagtaa tattttctgg agtgatacct catgcaagca
    17581 acacttatat aggtgtgttt atggttgtta taggaattat tttggcagct atagcaagtt
    17641 ttctatactt aggtgtttgt ttaggaagtg gaccgagaga tgggcttatg attgctcttc
    17701 agaaaaaaac taataaatct gtacgtcttg ttagaacaat tcttgaaata ctagcattag
    17761 ttgttgggtg gttattagga ggttctgtag gtattggtac gcttgtaagt gctttaggtt
    17821 taggatatgt attacaaata gtgtttagaa tatttaaatt tgacacaaaa ttgttgaaac
    17881 atagatttat tatagatgat ataagagaat ggaaggaaaa gaaaagcaat gaacataaat
    17941 gtaaatcaag tattgtaata aaaaatgagc agaattaatt atgctaaaat atatttgtag
    18001 tttatctaat ttatagtaaa gtcaaggaga ttttgaaatg gaattatggg atttatataa
    18061 tgctgatgga attaaaacag gaaatgttat aaaaagaggt aattctattg aagaaggtta
    18121 ttaccatttg gcagttgaag tgtggatttt aaatagtaac tctcaaattt taattcagaa
    18181 aaggtctaaa agtaaaaaga cattgccaaa tatgtgggga atgacaactg gatgtattgt
    18241 ttctggggaa gacagtttag aaggagcaat tcgcgaagca aaggaagaaa tagggataga
    18301 tataactaaa gatgagatga aagtttttag aagtatgatt catgaagata ctctttggga
    18361 tgtatactta gttaaaaaag aatatgatat atccaaagct attttacagg aggaagaagt
    18421 aagtgatata aagtgggtaa gcacagatga aataagacaa ttactaaaag agggtttgtt
    18481 ttttgaatat ccagagatat acgaattgct atatgagata gataataata aattaaatat
    18541 atgatgtaga gcagatttca gtataagtaa gattatttaa aatgtatctt ctctaaattt
    18601 taatattgtt ttatgaaaat taataagtta tttttagtat ttttctactt gttttttgag
    18661 attaaaataa aaagggcagt cattataaag tcataaaaat ttggggagga tttaaactat
    18721 ggaagataac aaaggattgg cacgtgacag ttcaaaatat aaaattgttt ctatatctgt
    18781 cgtagtaatt attctaatta cattttggta tatgttaaat atggtgcttt taacatttat
    18841 tatgactttt attttctata acttgcttgt agccacaaga aaacgaatta agaagttttc
    18901 ttctttaaat attccagatt cattgataat tatagtgtta tatgcactat ttgctatatt
    18961 gttagtattg attagctatg cagttgtacc aataattata gttcaactta cagagttgag
    19021 tagggttttt agtgattttg atgtaaatca atttgctcaa tctttaggac caaaattgta
    19081 tcctattgtc tcaaagctgg attttaataa atatatttca caagcagggc tacttatagc
    19141 atcaacagca acaaaagttg gaagttttgg agtaaatata ttattggcat ttttactgag
    19201 tttactcctt ttacttgaaa aaaatgaaat taaaaatttt ggagataaac tttctgatag
    19261 taagatttct tttatttata attcgcttgt attttttgga aagagctttg ttaaaaattt
    19321 tggtgaagta atgaaagtac aagttatgat tgcctttata aattctgttg tttctatgat
    19381 ttttttaggt ttcatgggat tccctcaaat atgggcttta ggatttatga tttttgtgtt
    19441 gggtcttatt ccagtagcag gagttatagt gtctttgatt ccattaactg taatagcatt
    19501 taatacagga ggaataacaa aggtttttgg agttttactt atgatttgta tagtgcatgc
    19561 agtagaaaca tacatattaa accctaagtt gatgtcgaat agaactaaac ttccagtttg
    19621 ttttgttttt attattttac ttgtaggaga acattattta ggtgtatggg gattactaat
    19681 tggagttcca atatttatgt tccttatgga tattctgggt gttaaattta cttctaggta
    19741 atatattaaa ataataattt atctttatat ataaattata aattgtttta aaaaagaacc
    19801 tataaataga catcattaat aaagacatct atttgatagg ttcaattttg ctttgtataa
    19861 atactataaa actaaataaa aagaaattta tttcatttca aaagtttcac aacttgcatt
    19921 tctttcattt atatgaactt tttcagcttt gcaaagttca tttttattgt atttacattt
    19981 tacagcttca caatgaatgt tatctgtatc aacttggtta gtttcattag aacgactagt
    20041 tataccagat gtatatttgt cttcaaaaga agcacaataa gtattttctg tagtagttgc
    20101 ttgcattcca tctactttta tactaccagc ataacaatat ccactagtat tataagcaca
    20161 attagtagca gcacaattta aattattatt tttcataaat aacctcctaa gttttattta
    20221 aacttattat gtgaagttat ctaaatttta tacacttatt tacaattaca tttatcacat
    20281 ttaacaacta catctttgga agtttccctt cctaaatttt tattaacatg atacacatca
    20341 acattttcag ttgatccaca tatagaacat ttaaaattgt tttctagtag ggttctttct
    20401 ttaaataact tccaatacat agaattgatg taatcattat aatttacctt gaggcatgtc
    20461 tcaagaaagt ttatgtatag attgtctaaa tctcctgtat ttaattctgt atattctggt
    20521 tcaaaatatt cacaacatcc tctaaaatcg ggctttgtat ctgaaataac acatctaata
    20581 tcatatctat agtctaggct aggcccctta aatgaaagat gtgtgcaaaa agaacaagat
    20641 gtttctggta gatttttttc aagttcatgt aatttattat tcataagtat tcctccaaaa
    20701 aatttatttt aagtatataa acgaatagat tattttaaaa cttttattta tttatattag
    20761 agatttagga taaatattcc aataaggagt aaatacttaa gtatttatta ctgtattaaa
    20821 taaaaaagag gcaaatctaa cttgagattg cctacttttt tatcattttt taataaaatt
    20881 tattctaagt attattttat ttagatttag tcagccaatt tagtatctgc tttgcttttt
    20941 aactttctac cagagcgtac agttaaaata gcatataata cagtaaatat ggcagctaaa
    21001 acatatgata tatttatgtt taagttaaat ccaatttgag cattaaatat ataactgaat
    21061 ataacaaagg aataaaacat accaggaatt aagcttataa tataattctt ttcttttatt
    21121 ataaggtaaa ctgtaatcat tgcaaatgca aatatggcaa tagtttgatt actccaagag
    21181 aagtatctcc acaatatatt aaatccagaa gcactaagct ttgcaaatat aaggatggct
    21241 atgacaggaa taaatataca gattgacaat ataacacgat gtttcttttc cttttggtca
    21301 taatgaaagt aatctgcaag cattaatctt aaagatctta aagctgtatc tccagaagtt
    21361 attggtaaaa caattacacc tattatagct atgataccac caatagaacc aagtaaatct
    21421 cttgcaacca aacctattac atcaggagaa cctactaatt ccttaggtat tcctttattg
    21481 taaataccca tagcagctgc agcccaaatc attgcaatta aaccttctaa aatcatcata
    21541 ttataaaaag tagtttttcc ttctttttca tttgaaactg atcttgctat aagagtagct
    21601 tgagttgagt ggaatccaga aacaatacca caagcaactg taacaaagaa tgtaggaata
    21661 agaggaatac catcaggatg aatacctttc caatttgcaa gacttaaatt agctaaatca
    21721 taaccttgtg taaagattcc aattccaaca ccagcagcag ataaaagtag aatagctcca
    21781 aatattggat atacctttcc tatgatttta tcaattggaa atagtgttgc acacaagtaa
    21841 tatagaaaga taagtccata aactatccag acaactggat tatttatagt cgatttcata
    21901 tttaaaattt gagtaacaac taaatcccca ggtgtataaa taaaaactgc accaactaaa
    21961 agcattaaaa gacaaaggaa tatattatag acttgaaata ctttattacc taaaaatcta
    22021 ctgataagag aaggcatttg tgctcctttt tctcttatac taatcattcc actcatatag
    22081 tcatgcaaag ctcctccaaa tacacagcca ataggtatta gtatgaatgc tattggacca
    22141 aacaatatac cttggatagg tcctagaatt ggtcctgtac cagctatatt aagcaactca
    22201 attagactat ttttccattt tttcattggg acatagtcta ctccatcact ttgagcaagt
    22261 gcaggtgttt ttctgtcatc tgggccaaat actttttcac aataagcacc gtataaagca
    22321 cctcctatta gtaatatagc caagccgatt aagaatgttg tcataatatc accccattta
    22381 taaaattttt tggtctttgt atacatatta tctaaatgtg tagatttata ttgaatttaa
    22441 ttctggacaa cctacaaatt ctataaagta ttacaactaa tataatttca gaaataaata
    22501 catatacata accatgtact tagtatacag gtatttggta atattttcaa tgttatagca
    22561 ataaagaata taaacaaaat tctgataata ttttacaaaa aaattaaaaa atataaaaat
    22621 tagtttaaat agatggagaa aaaaggaaaa tcaattaaga atataaatgt ctatatctta
    22681 acaatattaa gaggtttaaa attcttgaag aaagaatagt caagtgatat aatgagttta
    22741 caggtgtata tacactagta catatagaaa gcggtgcaat tatggataaa gatttaacat
    22801 atcaaatcaa agagctaaag aaagaaaaaa atgcaataat acttgcccat ttttatcaac
    22861 caccagaaat acaagaatta gcagatgcag ttggtgactc atattattta agtgagattg
    22921 ctagagattg taaagaagaa gtggttgtat tttgtggagt aaggtttatg ggagaaagtg
    22981 ctaagatatt atcacctgaa aaaactgtat tgatgccagt aagtaacgct gggtgtgcta
    23041 tggcagatat ggtagatgaa gaaggcgtga taaaattaaa acaacagtat ccaaatgctt
    23101 tggttgtatg ttatataaac tctacagcta aagttaaggc acattgtgat gtttctgtta
    23161 catcttctag tgcaattaaa atactagaaa acatagataa taaagaaatt atattccttc
    23221 cagataaaaa tttaggagga tatattgcag aacaatttcc agataaaaac tttatatttt
    23281 gggacggata ttgtaaatac cataacaata taagagctga agaaataatt gagttaaaag
    23341 ataagtataa aaatgcagaa gtattagtac atccagaatg taaaaaagaa ataagagatt
    23401 taggagatta tgtaggtagt acatcaggaa taataaaata tgctactaat agtaaaaaca
    23461 aagactttat aatagcaact gaagaaggta tattacatga attaaagaaa aataatccta
    23521 ataaaaactt ttatattcct ggtggaaaaa tactatgtac agatatgaaa aagacaacat
    23581 tagaaaattt atatagtaca cttaaaaata tggaaaatga agttattgta gaagatgaaa
    23641 tcatggaaaa ggctttaaat tcactgctta acatgcacaa attagcagaa ggatagaggg
    23701 atagacttat gaatttagaa caagatgttt taatagttgg aagtggagtt tcaggattat
    23761 actgtgcatt aaatttagat aaaagtttaa atgtgctagt agtatcgaaa tcaacaattg
    23821 aaaacaacaa tacatatctt gcacaaggtg gaatttcaac tgctagaaat attgatgata
    23881 tagaatcctt tgtagaagat acaatgaagg ctgggcagta taaaaataga gttgaagcag
    23941 ttcaagtact tgcagatgaa tctatagaaa atgtagggca gatagtagaa tatggtatgc
    24001 ctttagacaa agaaaatgga gagatagatt acacaagaga aggagcacat agtgtaaatc
    24061 gaatagttca tagtaaggat aatactggag aagttgtttt taaaacttta ttaaaagaag
    24121 ctaaaactag agaaaatata actcttatag aagatgcata tcttttagat atattaaaag
    24181 atggcaataa atgtatagga gctagaattt ttaaatctaa aaaagagatt catgtttttt
    24241 caaaaatagt agttttagct acaggtggaa ttggtgggct ttttaaaaat tctactaatc
    24301 aaagacatct tacaggtgat ggaattgcaa tagctttaag aaataatata aaaatagaaa
    24361 atttagaata tattcaaata catcctacag ctttttatga agaaaataat gaaggtagga
    24421 gaatgcttat atctgaatca ttaagaggag agggagctaa acttttaaat aaaaataaag
    24481 aaagatttgt ggatgaactt cttcctagag atgtagtttc aaaagctatt tttgagcaaa
    24541 tggaaaaaga taaattacct tatgtgtatt tagatgcaac acatttagat agtgaatatt
    24601 taattaatag attttctttt atttataatg aatgtttagc tagaggaaca gacataacga
    24661 aagaatgtat aaaggtatct cctgcacaac attattttat gggcgggata catgtagatt
    24721 tggattcaaa aacatctatg gaaaatttat atgcagttgg tgaaattagt tgtacaggtg
    24781 ttcatggagc caatagattg gcaagtaatt cattacttga agggcttgta ttttcaaaaa
    24841 gagcagctaa aaatataaac tcagttatag ataatgtaaa agttaagttt atagatgtac
    24901 cagatatgga tatagatata gaacaggtaa aaaaagaaaa taaaatatta gtcataaaag
    24961 aaattgaaag aacaagtgag gattttggcg atgaattatt tgattattga tagaatgata
    25021 caggatgctt tgatagaaga tgttccaagt gaagatataa caactaattc tattgtggat
    25081 gaaaattcta aatctactgt agatttaatt tgtaaacaag atggtataat agctggctta
    25141 ggtgtattta agagagtttt tgagatactt ggtgatgtag atgtaaaatt atataaaaat
    25201 gatggtgata gagtaaagaa tcgtgaaaag atagctgtat taacaggtag tactagaaac
    25261 ttacttgtag gagagcgtgt agcattgaat tatttacaga gaatgagtgg tatagctact
    25321 attacaagta ggtatgttga aaagcttgaa ggtacaaata caaaattatt agatagtaga
    25381 aaaacgatac ctaatcttag aatattagat aagtattctg ttaaagtagg tggaggatgc
    25441 aatcatagat ttaatttatc tgatggaata ttgcttaaag acaaccatat tggggctgct
    25501 ggtagtgtta agaaggcagt tgaattagct agaaaaaata cttcttttgt tagaaagata
    25561 gaagtggaag tggaaacttt agacatggta aaagaagcaa tagaagctaa tgcagatata
    25621 ataatgttgg ataatatgag tttagaaatg gcaaaacaag cagtagatat tataaatgga
    25681 agagccattg tagaattttc cggaaatgta aatttagata ctatagaaga tataggaaaa
    25741 attggtgtgg atgttgtttc tgtaggagcg cttacacatt ctgttaaagc tctcgatata
    25801 agtatgaaga atttgagaaa tatataaatt ttatattgaa ataaacttaa ttaaaataga
    25861 ctccttaaat tt
//
LOCUS       DAEPXW010000055        24649 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.056, whole genome shotgun sequence.
ACCESSION   DAEPXW010000055 DAEPXW010000000
VERSION     DAEPXW010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24649
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.056"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     regulatory      94..184
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            592..909
                     /gene="flgB"
                     /locus_tag="KRM55_002267"
     CDS             592..909
                     /gene="flgB"
                     /locus_tag="KRM55_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBH1594506.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            917..1321
                     /gene="flgC"
                     /locus_tag="KRM55_002268"
     CDS             917..1321
                     /gene="flgC"
                     /locus_tag="KRM55_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBH1594507.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            1331..1648
                     /gene="fliE"
                     /locus_tag="KRM55_002269"
     CDS             1331..1648
                     /gene="fliE"
                     /locus_tag="KRM55_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBH1594508.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            1673..3223
                     /gene="fliF"
                     /locus_tag="KRM55_002270"
     CDS             1673..3223
                     /gene="fliF"
                     /locus_tag="KRM55_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBH1594509.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEQEDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            3236..4306
                     /gene="fliG"
                     /locus_tag="KRM55_002271"
     CDS             3236..4306
                     /gene="fliG"
                     /locus_tag="KRM55_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBH1594510.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            4299..5030
                     /locus_tag="KRM55_002272"
     CDS             4299..5030
                     /locus_tag="KRM55_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBH1594511.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQADLMLLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            5034..6353
                     /gene="fliI"
                     /locus_tag="KRM55_002273"
     CDS             5034..6353
                     /gene="fliI"
                     /locus_tag="KRM55_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBH1594512.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            6384..6830
                     /gene="fliJ"
                     /locus_tag="KRM55_002274"
     CDS             6384..6830
                     /gene="fliJ"
                     /locus_tag="KRM55_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBH1594513.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            6859..8064
                     /locus_tag="KRM55_002275"
     CDS             6859..8064
                     /locus_tag="KRM55_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBH1594514.1"
                     /translation="MKIQADSYNIIKDIGDRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRREVSKQNISSDKPENSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILNNIEKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKLKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENII
                     DDDRVDLLA"
     gene            8082..8690
                     /locus_tag="KRM55_002276"
     CDS             8082..8690
                     /locus_tag="KRM55_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBH1594515.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            8717..9700
                     /locus_tag="KRM55_002277"
     CDS             8717..9700
                     /locus_tag="KRM55_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBH1594516.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            9713..9916
                     /locus_tag="KRM55_002278"
     CDS             9713..9916
                     /locus_tag="KRM55_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBH1594517.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            9916..10734
                     /locus_tag="KRM55_002279"
     CDS             9916..10734
                     /locus_tag="KRM55_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBH1594518.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKILSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLSDLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            10724..11419
                     /locus_tag="KRM55_002280"
     CDS             10724..11419
                     /locus_tag="KRM55_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH1594519.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIESVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKADSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            11431..11874
                     /locus_tag="KRM55_002281"
     CDS             11431..11874
                     /locus_tag="KRM55_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBH1594520.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            11889..12263
                     /locus_tag="KRM55_002282"
     CDS             11889..12263
                     /locus_tag="KRM55_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HBH1594521.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            12264..12929
                     /gene="fliP"
                     /locus_tag="KRM55_002283"
     CDS             12264..12929
                     /gene="fliP"
                     /locus_tag="KRM55_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBH1594522.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            12942..13211
                     /gene="fliQ"
                     /locus_tag="KRM55_002284"
     CDS             12942..13211
                     /gene="fliQ"
                     /locus_tag="KRM55_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBH1594523.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            13223..15037
                     /locus_tag="KRM55_002285"
     CDS             13223..15037
                     /locus_tag="KRM55_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBH1594524.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            15046..17121
                     /gene="flhA"
                     /locus_tag="KRM55_002286"
     CDS             15046..17121
                     /gene="flhA"
                     /locus_tag="KRM55_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBH1594525.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGDLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            17096..18112
                     /gene="flhF"
                     /locus_tag="KRM55_002287"
     CDS             17096..18112
                     /gene="flhF"
                     /locus_tag="KRM55_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBH1594526.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            18109..18987
                     /locus_tag="KRM55_002288"
     CDS             18109..18987
                     /locus_tag="KRM55_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBH1594527.1"
                     /translation="MIDQAQILRKIAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            19001..19702
                     /locus_tag="KRM55_002289"
     CDS             19001..19702
                     /locus_tag="KRM55_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBH1594528.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            19718..20140
                     /locus_tag="KRM55_002290"
     CDS             19718..20140
                     /locus_tag="KRM55_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH1594529.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRSNSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            20125..20310
                     /locus_tag="KRM55_002291"
     CDS             20125..20310
                     /locus_tag="KRM55_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH1594530.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            20351..21124
                     /gene="flgG"
                     /locus_tag="KRM55_002292"
     CDS             20351..21124
                     /gene="flgG"
                     /locus_tag="KRM55_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH1594531.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            21145..21906
                     /gene="flgG"
                     /locus_tag="KRM55_002293"
     CDS             21145..21906
                     /gene="flgG"
                     /locus_tag="KRM55_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH1594532.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            21929..22810
                     /locus_tag="KRM55_002294"
     CDS             21929..22810
                     /locus_tag="KRM55_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH1594533.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            22813..23187
                     /locus_tag="KRM55_002295"
     CDS             22813..23187
                     /locus_tag="KRM55_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH1594534.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            23219..24622
                     /locus_tag="KRM55_002296"
     CDS             23219..24622
                     /locus_tag="KRM55_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1594535.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNNVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
BASE COUNT        10193 a         2626 c         4619 g         7211 t
ORIGIN      
        1 taattattgg taattaaatt taaaaaataa aatatttaat tatacacaaa aaagatattt
       61 aaaaaatttg ttatttattg tatacttaag ttaaaactaa ataggcaaat ctagagaaat
      121 ctagtgacgc aaagctatag ggactaaggt ttatatacat aaactatgtc agccagttgc
      181 caaaaagagt cctaggtgta ttgtatacct aagaaaagtc tataatgact gcctttttgg
      241 cagtcatttt gttatggaaa aatcacttta tttcagtaga aaatacacat aataacatat
      301 tttaccaatt ataacataaa ataaagaaaa attatctcaa aaagttacta ttttacaaaa
      361 agagcaactt ttcgaagaaa tatttaaata catattaaaa tttttttata ttttcatggg
      421 acttcattaa aaaaatatta gttttcttac taaattgata cattattgta ttaatgtaat
      481 ggaaatgcga ttaatttaaa taaataaaga agtcattttt tgtaatatag caacttcatt
      541 ttttttatta ataaacaaaa tagataaaat atattttgag gaggggtgag tgtgaataca
      601 tatgacatta taaaaatggg attagatgca actaatctaa gaagtcagac aatagcaaat
      661 aatatagcaa atataaatac tgaaggatat aaaagacatt atataacttt tgaagaaaca
      721 ctaaatgatg ctatgcctaa aatagaagaa aaaacagaca attctaaagg tttaagagta
      781 gatggtaata atgtagacat agaagaagaa aaagtaaatc aagcaatggc aacattacaa
      841 tataatgctt tgataagttt tgcaaatgga aaaatagcaa tgaccaaatc aataataagt
      901 gggaggtaat tagaagatga gtgtgttcag tggaatgaga atatctgcta gtggattaac
      961 agcagaaagt ttgaaaatgg atatcatatc atccaatgta gctaatataa atgctacaag
     1021 aggtccaaat ggagaagcat ataggagaaa agttgtttca tttgaagaaa actatgataa
     1081 taaattaggt atgctaggag taaaagttac atctgttgaa gatgataaat cacctcttaa
     1141 agaagtatat gacccatctc atccagatgc aaagccaaat ggatatgtag aatatccaaa
     1201 tgtaaatata ttggtagaaa tgacagattt aataacagct tcacgagcat atgattctaa
     1261 cgtagataca ttgaatgctc agaagtctat gatatcaaaa gctttggaaa taggaaagta
     1321 gggataaatt atgccaatta cacaaattaa caatttaatg caaggtgcaa agttagataa
     1381 tttgattgga gaagcaaagc cattaactct taataataaa gaagaaaaaa agaattttga
     1441 agatgtaata atagatacta tagataaagt taattttcaa caagtaacag cagatgatat
     1501 gaaagaaaaa tttataaaag gcgaagatgt ttctatgcat gaagttatgt taataggtca
     1561 agaagcacaa ctatctatgc aatatttaat agaagttaga aataagattc atgatgcata
     1621 tcaagaaatg aataaggtgc aaatttagcc ttttgaacag gagtaataat caatgataac
     1681 cagttttaaa aataagatta aggagcaagt tgctaaatct aggacaaaga taagttcttt
     1741 aaaaaaggga actaaaatag cattaggtat aggggttatt gctatatgtt tagcgctagt
     1801 atttacagca atatctgcga gcaaaaataa gtatgcagtc ttattttcag aactagatgc
     1861 tcaagatgct gcagatatat cagcagagct agagtctaaa aagatagata ctaaggtaaa
     1921 aggaagtacg atttatgtac ctagaacaga agttgataag ttaaggctgg agttagcgcc
     1981 aagtcttaca ggtggttcta aaggatttgc actaatggat gatagttcat caatagggct
     2041 tactgatgaa gaatttcaga ttaagaaaca aagaatgata caaggtgaaa tagaaaaaac
     2101 aataaagagt tttccacaag tggaagacac tagagtacat ataacatttg gagagtcatc
     2161 agtatttgag aaggaggctg ttccagggag tgcagcagtt tatttgatgc taaaaccagg
     2221 gacgacttta gaaaaaaacc aaataaagtc tgttatggca cttatatcag gaagcgttac
     2281 aaatatacca gagaaaaatg ttcaggttat tgataacaaa atgaatttat tatctgaagg
     2341 tattttggag gatgaaaatg ttgatgaaaa taatcaacca ataaatagtg gcattagtgt
     2401 tgataaaaat aaggcatctg aacaagcatt gaataaacaa ctagaaaagt ctattttaga
     2461 aatgctagaa ccgatatttg gtaagggaaa ggtgaaagct acagtaaatg ctgatttaag
     2521 ttttgataca gctgaaaaaa ctgagataaa aattgaccct gataaagttg caataaagga
     2581 gacaaggtcg aaaaattcat ctaaatctgc tgcaaataat gttcaaggtg tagatgctaa
     2641 catgaataac caaggaaata acaatggtac taatacagaa gatagtttag atgagagttt
     2701 tgagtatgaa acaggtaaga ttgaaactca cactatagtt gcgcctggag aacttaatag
     2761 attgacagct tctgttgcaa tagatggaaa aatagctaaa ggtgttcaag ctgatgtaga
     2821 ggatattgtt aataatgcta taggtatgga tggagcgagg ggagatactc ttagcgttgt
     2881 ttcaatggta tttgacccag aaggtaagaa agaggctaaa caagagctgg aagagattaa
     2941 aaaagaagga tttaaaaaga acataataaa agcagttatt ggagtagtag cagtaatagc
     3001 agttggagct attggatact taatatataa gaaaagaagt gaacaagaag atatggatta
     3061 tgaagatgaa gactatattt ctaaatctga ttctgttgat aggaaagata atcctctatt
     3121 aggagatgac ccagaactga cattagagga agctgttaaa atgtatgcag aagaaaagcc
     3181 agaccaagta acagagataa taaaaacttg gttaaatgag taagggggat agaaagtgtc
     3241 cacggaaatt acaaatgtta atgcgtttga cttaagtgat ataaatgaaa gtgataagaa
     3301 tgagaaggta gaaggtgagg gtttaaaaaa agctgctgta ttattaatga cattaggccc
     3361 aaatgtgtct agtgatataa taaaaagctt gcctgataaa caagttcaaa aaataggttt
     3421 ggaaattgca aatatttctt caatagcttc aaaagaaaga agagaaatct taaaagagtt
     3481 tgtagaaata aatagggcaa aagattatgt tatagaaggt gggcttgaat atgcaagaga
     3541 gttgttaagc aatgctttag gaaatgctaa agcaaacaaa ttacttgaag gtatatcaat
     3601 aaatacaagt acaaagcctt ttaaacatat tataaaacta gatgtaaaga agatattaga
     3661 aatacttagg aatgaaagtg cacaaactat agccgtttta cttgcacata tggaaccaga
     3721 aaatggagca gaagttttat catacttaga ttttgattta caaaatgaag tagctatgag
     3781 aataagctca atgggttcaa tatctccaga agtaataaag gtaattgaaa gttcattaga
     3841 agataaatta cattcaataa gtggtgatga ttttaatgat tatggagggg tgtctacctt
     3901 agttcaaata ttgattaatt ctgatagaaa aacagaaaag aatattttgg gaactattga
     3961 agaacaaaac ccggatttag cagctcaaat taaatctcat atatttgtct ttgaagatat
     4021 tgtcaagtta gatgatataa gcatacaaaa agtgttaaaa gaagtgacta tgaaagattt
     4081 agtatatgcc ttaaaaggtg tagatgatga gatttcagat gctatatata gaaatcaatc
     4141 ttctagggca gcagatgcac ttaaagaaga aatggaaatg gttggtgtta taaaggttac
     4201 acaagttgag gcttctcaac aaaagatagc taatatcgta agaaaacttg aaagagaagg
     4261 tgccataact attgtaagga attttggtgg tgactttgtt gaataataag attattaaaa
     4321 gtaaaaaagc attatataaa ggagtgctag atttaaccat aatagataaa gttagagtgg
     4381 gagaatcaaa tgtaaataaa gaaaatgatt gtagatttag ggatgaggta ataaaagaag
     4441 ctatagaatc tgctgagata aaaaagaatg agatattaga agaagcaaaa ataaatgcac
     4501 aaaatataga aaagcaagca tatgaaaaag ggtatagtca aggtcaaaaa aatggatatg
     4561 aggatggata taaagagtca tatgatgaat atacccaaaa agctaaagat gaagcagatt
     4621 ttataaaaaa tcaggcagac ttaatgctat tacaagctaa tgagaagatg actgagtaca
     4681 taaaagaaaa aaataaagag attgtaagac ttgctattaa tatggctagt tctgttctaa
     4741 aaaagcattt tgaagatgaa gaatctatga gtgatttgtt aaagcaaatt attcaagatt
     4801 atgaaggaag tagttcattt atagtaagat gtaattcttt ctataaagat aatatagaga
     4861 aagagtttga attattcaaa gaggaaacat cactaaaatc aagtgtattt gttattgcag
     4921 atgatagtat agataaaggc aatgctatta tccaaaagga aaatggaaga ataatagttg
     4981 gtattgattg tgctatggaa aaactaaaag aagaattgct tggtgaataa agtatgtata
     5041 aaactgatat atctatagat tttgacaaaa taaataagaa aatagaaaat ttagaactca
     5101 ctatatcaga aggtagagta aagaagataa taggacttac tgtagaagtt gaaggaataa
     5161 aagcttttgt tggggagtta tgcgttatat acaaccaagt taataaacca gtgaattgtg
     5221 aagtagtagg ttttaaagat aaagaagtca tattaatggc gttgggagaa ttaacattga
     5281 tagcacctgg ttgtaaagtt atttctaagg ggataccttt aagtgttatg tgtagtgata
     5341 atttactagg taaagtactt gatggtcttg gaaatcctat agacaactca gatgctgttt
     5401 taggagatag atacaacctg aacaatgaac ctcctgaccc aatgaagaga aaaaagatac
     5461 gaaatataat ggaaacaggt gtaagagcaa tagatgcatt tactacttgt ggtgaaggac
     5521 agagaatcgg catatttgca ggaagtggag taggtaagag tacgactcta ggtatgattg
     5581 ctaggaatgc aaaagcagat gtaaatgtaa ttgctcttat tggagaaaga ggaagagaag
     5641 tactagattt tattgataaa gatttaggtg aagagggaat gaaaaaatct gttgttgtgt
     5701 gtgcaacatc agataaagcc cctttagtta ggttaaaagg tgctcttact gctactgcaa
     5761 tagcagaata ttttagagac caaggcaaaa aagtaatact tatgatggat tcagtaacta
     5821 gatttgctat ggcacaaaga gaagttggtg tagcaatagg agagccacca gctcaaaaag
     5881 gatatacacc atctgtattt gcaatgttgc caaaacttat ggagagaaca gggacatcag
     5941 ataaaggttc tataactgca ttttatacag tattagttga tggagatgac tttaatgagc
     6001 caatagcaga tacaacaaga gggatacttg atggtcatat agttttatct agagacttgg
     6061 caaataagaa tcactatccc tctatagatg tattaaacag tttaagtagg cttatgaatg
     6121 agattgcttc aaaagaagac ataaaaatag cttcttttgc aagagacatg cttgctgagt
     6181 atagagaagc agaagatttg ataaatatag gtgcgtatgc ttcaggtaca aataaaaaaa
     6241 tagatgaagc aatctattat catgagcata ttattaattt tttaaaacaa gggataaatg
     6301 aaaagagttc ttttaatgaa actataagta gtttgagaag agtttttgaa taaacaatta
     6361 aaaaaatatt tgaataggtt gtgatggaat tggataaaaa ctttaagttt agattacaga
     6421 aagttttaga cttaaaagtg aaagatgaag aagagataaa aatggaattt gctaagattc
     6481 aacaaaaaaa aatagatata gagactaatt tagaaaactt agaaagtaat tatagcaaat
     6541 attctataag taaaaataac gatagtattc aaaatcaaaa aataactatt aactatttac
     6601 tagctttaaa caattctata atggatttat cagaagagtt ggataagtca acaaatgaac
     6661 ttgaaaaagc tagaaagcag cttataagca aacagataga gagaaaatca ttagaaaaat
     6721 taaaagaaaa aaagtatgga cagtattata aagaagaaaa tttaaaagaa caaaacacta
     6781 atgatgagtt tgcaagtatg agttatttaa ggaatagaca agttctataa gaatagtagg
     6841 aagtgaggat attattgtat gaagatacaa gcagattctt ataatattat taaagatatt
     6901 ggggatagaa aaagttcatc taagaacaaa aatataaaaa ataataaatt tgaagataat
     6961 ctatataagg caacagacca taaaaaggtt aaagatagaa gggaagtaag taagcaaaat
     7021 attagctcag ataaaccgga aaatagtgat aatgagtgtc atttagatga agataaaagt
     7081 aatcacttag aagatgaaaa tacatatgaa aaagattgta gtaagaataa tgaagctttg
     7141 cagcaattac tgaatctttt aaaggataat tataaaaaag ataaagatat aaacactata
     7201 ttgaataata tagaaaaact aagtatatca gatgaattaa aacaagaact taagcttaat
     7261 aaaaatatat taaataagat tgcaaatcaa aattcagagc taaataaagc taatataaat
     7321 aactctaatg atatagaaaa tttagacata gttaaattaa gagaactttt ggaagataat
     7381 gctaataaag atattgaagt aattactaaa actacagaaa atgatactaa aaatatagat
     7441 ttgtatagtt ttgatagcaa tagaatggat aatcttaact caaataaaca gaaagatgat
     7501 agctctgata ttttggaaaa actagcaggg gtaaatggaa ataagagtgg gaattttgga
     7561 caagtaataa ataaaaatgt tgatatgaat aaacttaaaa atgataatgt caatttaaaa
     7621 cagatagaat caaatgtaat ggatgactct ataaaagcta ttaagcatat gaaaacaaat
     7681 gatatacaag aattgacaat taaattaaga ccaaaagaat taggagatat gaatatacaa
     7741 ttgttaaaag atggtgaaag tatgagagct gttgtgactg ttttcaataa agatgtcttt
     7801 gactctataa ataaaaacat agcagattta aagcaacatc ttgaacttac taatgtaaat
     7861 ataaaagatg tatcagtgca aatgcacagc gataatacaa atacatctga tacctttgat
     7921 aaagcatttg aacaacagaa tagacaaaat aaccaagaaa acatgagtaa gaagaataca
     7981 aatgataagc ataataatgt agtcatagaa gatgacatta aagaaaatat tattgatgat
     8041 gatagagtag atttactagc ttagtaaggg ggaagtattg catgtacgga atagcaacgg
     8101 ctttggcagg aactcaggga aactacaggt caaataactt aagccaactt gaaagaaata
     8161 ttaatgatat tgccaataaa caagttagaa gcaaaggaaa tcagacagta acagacaatg
     8221 ggactccaat tataggacaa ggtgatgatg ctgataaaga cttgtttatg aagatacttg
     8281 tggcacagat gggtaatcaa gacccaatga atcctcaaga cccaacagaa tatgtgtcac
     8341 aattagcaca gtttgcaact ttagaaaaga tgtcagctat gaatgagaag ctagatgtac
     8401 ttttagcctt aagtaattcc actctaataa actctgcttt gagtatggca acatcattaa
     8461 ttggtaaaga agtagaagta tctggggaag agaaagaaga tgaaaacatt gtaggagtag
     8521 taaagtccac atatataaaa gatggggaag tacacttaga attagaagta gatggaagtg
     8581 acaaaactgt aggtgttaaa tatgaaaaat tacttaaaat aggagaggta gatgaaaatt
     8641 caggagaaga aaatgattct tcagaacacg aatctccaga agaagcataa tattaaatga
     8701 gaaaagaggt aaattcatga taaaagcaat gtattcaggt gtaagtggaa tgaaagcaaa
     8761 tcaaacaaaa ttagatgtaa taggtaacaa tgtagccaac gctggaacta cttcttttaa
     8821 gaaaagttca gctagaataa cagattcatt ttatcaaact gtactatatg caagtgctcc
     8881 aacagctgca ttaggaggaa caaacttagg acaagtaggt gtaggtagta agatatcaag
     8941 tataaataaa gatatggtac aaggaaatgt acaaccaact aatagaccat ctgatttaat
     9001 gatagatgga gatggatatc ttccagtagt aagacaagga acagttatgt atacgagaga
     9061 tggttctttt aatttagata caggatttaa agcagctgat ggtgctttga agaatattaa
     9121 aggtggaaga cttgtaaatg gtgatggata tatgttacaa ggtatgattt atgatgggga
     9181 atataaagct gatactggag aatttgttaa aaagggtgat gctaaaggaa aagagcctat
     9241 tgtaatacca cttcaaagta taagtcctaa ggatggaaca gttcaaaatg tactagagta
     9301 taatatatca aaggatggaa cagtagaatt tttattgagt gatggtcaaa gaactcaatt
     9361 tgtctatgat atacctgatg gtgctaaggt aggagataca cctgctggaa tagataaatt
     9421 aaaaggtaca atacaaaaag tgcaaacata tgcattccaa aatccagcag gactagatgc
     9481 agaaggagga aacttgttta aaccatcagc aaactcagga gacccacaaa tagcaggagc
     9541 tacaggaaca ataatacaag gggcaataga agcttccaat gtagatatag cagaagaatt
     9601 tacagaaatg ataatagcaa gtagatcttt ccaagcaaac agtaaaataa tatcgacatc
     9661 agacgagata cttcaagaaa taataaatct taagagatag taggtacata ttatgataag
     9721 agtaacggat ttaaacggaa gaaaatacat attaaattca gaccttatag tgaggattga
     9781 ttctgtacca gaaagtagga ttcttcttac aacaggagaa aaaaaccttg taaaagagtc
     9841 ggtagatgag atagtagata aagtaataaa gtataaaaga aaaataaatg taggttatat
     9901 taggagcgaa aaataatgaa aaaaacagat tcactgacat ttattggact aatagtatct
     9961 acagtattag ttttagttgg tgccgcaaaa ggaagtagtt cagggttaaa gaattttttt
    10021 gatgtttcat caatattaat cacagtgctt ggttcatttg gagctctaat gattacattt
    10081 actatagatg atataaaact tataaaaaat gcattacaat actcatttaa gacaatgagt
    10141 gtatcaaagt tagatttact agaacaattt aaaatacttt ctaaaaaagc tagaaaagaa
    10201 ggtcttttat caatagaaag tgatgtaatg ggaatagaag atccatttat gaagaaaggg
    10261 ttagagctgt gtattgatgg attggaaatc aatgagataa ggtctatctt agaactagag
    10321 atagattctg ttgaagatac aaataacaga tactctaaac tatttaaaac ttggggaacc
    10381 tttgcacctg cttttgggat gttgggaact ctaataggtt taatacaaat gctatctgac
    10441 cttacatctc cagatttaat agcatctggt atgggaaagg cattaattac aacgttttat
    10501 ggttctttac ttgctaatat cgctttgaac ccaattgcat ataatataga tgagaagact
    10561 gaaaaagaaa tttatgtaaa ggaaatgatg cttgaaggta taataagcat acaatctggg
    10621 gagagcagta tagtagttga ggaacgttta gccacatacc tttcaaataa tgagaagtta
    10681 gaaattatga aatccaataa aaatacagaa agagcaatga gcaatggcgc gtaaaaaaaa
    10741 taagaaaaag gatgagataa atccagatgc atggctggct acttatgcag atacgataac
    10801 actgattctt acatttttcg tattattgta tgcaacatca gttgtagata tggaaaaatt
    10861 taaaaacata gcagatgcgt taaaaggtca gttttctggg acaagtatat ttagtacagg
    10921 ttcaagtaca agtgagaagt ctccaataga gagtgtttta gtggataaaa atgataagtc
    10981 aaatttagaa caggatttaa aagataaagt taataattct aacttacaaa atagtgtaac
    11041 agtcaaagat gatagtagag ggattttact agaactagat gattcaattt tatttgactc
    11101 tgggatttct gaattaaaag cagatagtaa agccactctt aataaagtat atgacatgat
    11161 aaagatgatg aaaaataaga tagttataga aggccatact gataatgtac ctgtaaaatc
    11221 aagtacacat gaatccaatt gggatttatc ttctagtaga gcagtaagtg ttgtaagata
    11281 ctttgtagaa gaaaagggca tggaccctag actattttcg gcaacaggat gtggagagta
    11341 tcaacctttg gtttcaaatg aaacagcaaa gggaagggct gagaatagaa gagttaatat
    11401 acttataact attgactagg aggaagaggt ttgttcaaaa ataaaaagat tattataatt
    11461 attttgatac tgattatttt ctcagcggga gcaggttttt ttatattagg agaaggtgga
    11521 aataaacaag ttgacaagat tgcaggtttg tttattccaa caggaaaagg taaagatgaa
    11581 gtaaagaccg aaaatcttga cttagaagag atggtattaa agctagctga tgaaggtgta
    11641 agatatttaa aagtatcaat aactgtatct tatgattctt catataaaga tatagaaaaa
    11701 aatacgcctt taattaggga taatattata aattgtttta tggcaaaaag ggcagatgat
    11761 tttactgctg ataatttaaa gaatataaaa gaagaaatta aaaatacatt aaatatacaa
    11821 ctaggtgaaa atgtaattca aaatatatat ttcacaaata tagtagtgca ataaaaggat
    11881 ggtaagacat gatactttat ttactaaaaa tattaatatg tatcccaata attttaatat
    11941 tgatagtctt atctttaaaa attagccaag gaactttatt aaaaaaatat aatgataaat
    12001 atgtaaaaat actagatatt gtaaatataa gtaaaaacaa tagcataata attttaaaaa
    12061 taggtgaaga aggatgcatt atggcatctt cttcttctag catgagtaaa ataaaagatt
    12121 tgaccaaaga agaaatatta aaaatagaaa acgacattaa agaaagaaat tttaaaattc
    12181 aagattttaa aatggaaaga attaaaaaga aatatgattt cagtagatat attggaaaat
    12241 ttacaaaaaa ggaagataag taaatggaac tattatcaaa attacctttg gctgatgtac
    12301 catatacaag ttcaatgcaa ttgtttttat ttctaactgc attaatgttt ttaccatttg
    12361 taatgttcat gatgacaagc tttgtcagaa tagttataag tttatcattt ttgaaatcag
    12421 cattaggagc acagcaagca attccaagtc aaattttggt aggacttgca atagtattga
    12481 caatatttat aatgagacca gtattaaatg agataaacga aaaggcatta caaccatata
    12541 tgaaagaaga agttactatg gaagaagcta tgaaggaagc agaaggacct attaaagagt
    12601 ttttattaac acaaaccaga cagacagatt tagatttatt tgtagaacag gctggtttaa
    12661 aagaaaagaa attaactcgt gaaaatatac cactatctgt tgtagttcca gcatttgcta
    12721 taagcgaact aaaaactgct tttcaaatag gttttttaat atatatacca tttttgataa
    12781 tagaccttgt tgtggcaagt gttttgatgt ctatgggtat gtttatgttg cctccagtca
    12841 tgatatcatt accatttaag ttattattat ttgtaatggt ggatggatgg aacttgatag
    12901 taaaaacatt gatattggga tttggatagg agaaaaatag tatgagtgaa tttatgataa
    12961 tgagtgttct taaaaatggc atgtttacag gagctatgat tgcagctcca gtactcattg
    13021 tttctcttgt agttgggctt ttaataagtg tgtttcaagc tacaactcaa atccaggagc
    13081 aaactttgac ttttgtacca aaactaatag ctattctttt agtagtagct attggtggaa
    13141 gctggatgtt acatactctt attagtttta cttctgagat attcaatatg atatctctta
    13201 taactaaata agtaggatac atatgatttt tgtatttatt agaatagtag cattctttgg
    13261 aacactaaga atactatttc cagctggtac acctgcttta tttaagtcac tctttgcaat
    13321 cattatatca atattgattt caagtactat gcaaattgaa tatgcaacaa atatagacaa
    13381 cattgtattg tttaccttat atggtgtaaa tgagaccata actgggatta tgcttggata
    13441 tataaccaac ctatgttttt atagtatcag aatggcgggt tctatgatgg accaacagat
    13501 gggattatca atgattaata tgtttgaccc aaattcaatg actcagacaa ctttaattga
    13561 taatcttatg aactggacag cacttatgat attttttagc atggatggtc atcatgtttt
    13621 aattagaggt ataaggtata gttttgagtt aattccaata ggaaaaccat ttgtagataa
    13681 taacatagat tatataataa acatatttgt gcagtgcttt ttaactggat tcaaaatagc
    13741 aatacctatt gtactttgtc tgcttatggc agattttatt ttagggctta tatcaagaag
    13801 tgtacctcaa ttaaatgtaa tgatagttgg tatgccatta aaaatattgg ttggtattgc
    13861 attatttatc atatcaatac ctttaattgt caatcaaata agtcatttat taagtcaaat
    13921 accaaagatg tatgagggaa cttttgcact agctcctatg ttttttatgg gttcagcaga
    13981 taaaacagaa gaagctactc caaagaaaaa gggagaacaa agaaagaaag gtaatatagc
    14041 aaagagtaga gaattacccg ttgcaatgac tctacttgca ttcaccttat tagtacctac
    14101 attattttca tatgtagtag atacacttaa atcttcgctt aattattttt tgagtctaga
    14161 tttttatatg aacataaatt attcaaacct agagaaatta gttatagcag gattaatgga
    14221 tttttttaag atatttttac caatagctat tcccttttta gttttaggca taatagcaaa
    14281 cctatttcag gtgggaatac tgtttactgg tgaaacttta aaaccaaatt tatcaaaatt
    14341 aaatccaatt agtggattca aaaacatgtt ttctatgaga agtttgtcaa ccttaataaa
    14401 ggatacagcg attatatcta ttttggctta cataggatat acattcttcc aagataatta
    14461 tttagatata ttaaagttag gtaacatata cctaccaact ttaatgtaca cagttaaaga
    14521 cttagtatat tcaatattga gtaagatttg tgtagctatg atagctatag cagttgcaga
    14581 ttatgtttat caaagataca gtcataaaaa gcaactgaga atgacaaaac aagaagttaa
    14641 agatgaatat aaaaactcag aaggagaccc agaagtaaaa gctaagataa aacaaaaaca
    14701 aagacaaatt tcgtctcaaa ggacaatgca agcagtacca agtgctactg taatagtaac
    14761 caatccaacc cacttatcta tagcagtgag atatgaaaaa gggaaagacc aagctccagt
    14821 agtggtggca aaaggtgcag attatttagc ttttaaaata agggaaattg caaagggaaa
    14881 tgacatacct ataatagaaa acaaacctat tgctaggttg ttatataagc aagtagaaat
    14941 agaccaagaa attccagagg acatgtatca agcttttgca gagatattag tggcagtata
    15001 taaaatcaaa aatagataca aagtccccaa aaggtaggat aagtaatgaa taagtttaat
    15061 ttaaaggaaa atatggatgt aatagtggca tttggtgttg tagggattgt tcttatgatg
    15121 atagtgccat tacctacatt tatattagat attttactgg caattaacat aagtttatct
    15181 gtgctaattt tactaatgac attatttaca acaaatgtac ttgatttatc tatatttcca
    15241 acagtgttac ttgtgacaac actatttaga ttgggattaa atctttcatc aactagattg
    15301 attttaacac agggatatgc aggtgaagtt atagaggcat ttggaagttt tgttgtaggt
    15361 ggaaattacg tagtaggaat aattatattc ttaattatat taattgttca atttgttgtt
    15421 ataaccaatg gttctggaag agtatctgaa gtaacagcta gatttacgtt agatgccatg
    15481 ccaggtaagc agatgagtat agatgcagat ttaaatgcag gagttataga tgacaaaact
    15541 gctagaaaaa gaagaaaaga gcttcaacaa gaagcagatt tttatggttc tatggatgga
    15601 gcaaataagt ttgtaaaggg agatgctata gcaggtctta tagtaacggc aataaacata
    15661 ataggtggaa ttgtaatagg agctgtaatg ctgaatatga ctcttatggg tgcagcacag
    15721 acatatgtaa gacttactat aggggatggt cttgtaagtc agatacctgc tctattaata
    15781 tctacatcag caggtataat cgtaacaaga gcttctactg atgaaaactt tggtgactta
    15841 gtaggtaaac agttaacggc aataccaaaa gcagtaatga tgactggttg tgttctaatc
    15901 gtacttggta tgatgcctgg attacctaaa ccagcatttt tttcactagg tataggagct
    15961 atagcagcag gttacttttt aggaagagaa aagaaagata ctttagaaga cttggagttt
    16021 gaaaaacctg atatggtaaa tccagataaa aatgaagtag aagatgtaac aaatttaata
    16081 aatgtagaat caatagaagt agaaattgga tatggtttaa tatctttagc tgatgaatca
    16141 gcaggaggag atttacttca gagaatagca tcaataagaa gacaatgtgc aatagacatg
    16201 ggtatagtcg tacaacccat aagaataaga gataacttac agttaaatcc aaaccaatac
    16261 aatataaaaa taaaaggaaa tgtagttggt gggtatgaga taatgcctaa tatggtttta
    16321 tgtatggatc ctatgaatca aggatttagt atatttggaa taaagacaat tgaacctact
    16381 tttggaatag aggcactttg gatagaaagt gacaaggtag aagatgcaga gttaaagggt
    16441 tatacagttg tagattcatc cacaatactt ataactcact tgctagatat aataaaatca
    16501 aatgcacacg aattactggg aagacaagaa gttaagacta ttatagatgc agcaagagaa
    16561 aattatagtg ctgtagtaga tgaattgata ccagatttga tgacacttgg tgaaattcaa
    16621 aaagtactta aaaatctgtt aagagaaaaa gtaaatataa aggatagagt tacaatactt
    16681 gaaacgcttg cagaccagtc tagaaataca aaagatatag agcttcttac tgaatatgta
    16741 agaatagcct tggctagaag tatttgtaat aatttagttg atgatgataa gacaattgta
    16801 gtggctacat tgtctccaga aactgaagag ttggtatcta ataatttaca gaggtctgta
    16861 aatggaactt atccagcagt tgacccagaa aatacaaata aaatatttga aagtatacaa
    16921 gaagtaatga gcaatgtata tttcaatcat aatataccag taatagtagt atcaccaaag
    16981 ataagagctc catttagaaa attagttgaa attgtatatc ctaatttgac tgtattatca
    17041 ttaaatgaaa tacctaacga tattaaaatc aaagcagaag gtgtggtgag catatatgat
    17101 gacgaaaaag tatacagcta acacaattca ggatgctatg aatctagcca aaatggaatt
    17161 gggtgacaat attacattaa tagataaaaa agaggtaaga aagtctggaa tacaaggtat
    17221 cttttcaaag aaagatattg aactaactat tggatgggaa aagagagaaa atgtagaaca
    17281 aaaagattta aaacgagaga tagaacaatt aaagtcaatt attaacaata tggggtttga
    17341 taataagaat gataatgata tagataaaat atgtaaaaat ctactaagtt tagaattgaa
    17401 tgaagaaatt gtagaatcta taagaattga tttgcaagaa atgaagttca atggaatcga
    17461 tacaagtaaa aatttagtag aaattttaaa gaaaaagatt aaaatagaaa atcaagtaat
    17521 aaatggtaaa attgctctag tcggaccacc aggagtaggt aaaacgacta caatagcaaa
    17581 gttagccgca aaattagttt ttgaagaaaa taaaaaagta ggagtaataa ctatagatac
    17641 atacaggatt ggtgctgtag aacagttgaa gatatatact gatataatga atattccctt
    17701 taaaggggta ataagtcctg atgaaatgga attggcactt gacgagatga aagattgtga
    17761 tgttgtatta atagatacaa caggtagagg ctacaaaaac tctatgcaaa tactagaaat
    17821 caaaaatctt atagataaag ctgaaactga taatatacat ttagttttga attgtacaac
    17881 aagagaaagt gatacaaaag caattataga ttcatataga aatgtgaatt ttaaaagctt
    17941 aataattaca aagctagatg aaacaataac atatggctca atatttaaca taatgaatta
    18001 tgcacaaaaa ccaatatcat atattacaac aggacaaaat gttcctgatg atattataaa
    18061 acctaatgaa gataagatta taaggttact attaggagtt gaaagtatat gatagaccaa
    18121 gctcaaattt tgagaaaaat agcaatggaa aaaagaggac ttgatgagtt tatagtagag
    18181 aatgagaatg tacctaagat aattacaata gcttctggta aaggcggtgt tggaaagagt
    18241 aatctcgcta caaatttgtc tatatgcttg accaaactta ataaaaaagt tcttatatta
    18301 gatgcagaca taggaatgtc taatatagat ataataatgg gggtaaatgt aaaagggact
    18361 ataattgatg taattaatgg cgaaaaaaat atagaagata taatttcaca gactaagtat
    18421 ggtgtaaata taatatctgg aggttctgcc cttaatcata tagaagactt tacagaagct
    18481 caaagaaata agtttataca tagcatagaa caaattcacg atgtggattt tataataatt
    18541 gatacaggag ctggtatgag caaaagccta ttgtcattta tatactgtag tactgaattt
    18601 ttcttaataa caactccaga accgacatca ttgactgacg catatagttt attaaaagct
    18661 ataagtaatt ttggcataaa gagaagtgca aatataataa tcaatagggt aattgattta
    18721 gaagaagcaa aatctacata caaaagaata aaaatggttg tggacaaatt tctaaacctt
    18781 aatctagaat tgtatggata tataatagat gacaaaaaag taagtttatg tgtaaaaaaa
    18841 cagataccat tcattttaga atatcctaca agtattgcat caaaatgtat tatagccata
    18901 gcaaagagaa tggtaagtca gtcaagagaa gatattgttg ataataaaag ttttctaaga
    18961 aagatgttta gtatatttaa aagctaagga ggcgtagtta atgaatagag aagaattaat
    19021 aaaagagaat atgcctcttg taaagagtat agcaagaaaa ttttttatac cagggaaagg
    19081 ttttgaatat caagacttag taaatagtgg agtcattgga ttgattgatg caataaataa
    19141 atttgatgct gaaaaagggg caaagttttc tagttactct tatataaaaa taaaatctgc
    19201 tatattagat gaaattagaa atcaaagtcc aatttctaaa cataatctaa ctaaagtaaa
    19261 taagtataat agagtggtag aaaagttgca atctaaatta ttaagagagc caacttcata
    19321 tgaaattgca aaagaattaa aggtttcaga aaaagaactt catgatatcg aaagtaatat
    19381 agatatgtta aatattgtat cattaaacta tgtaatcttt gaagatacaa atgaaactgt
    19441 acaagatgta ataagtgata gagaagagga agctccagaa aatataatag aagaagaaga
    19501 aaagttagag attctatcca aagcaattag taatttaaat gaaagagaaa aattaatact
    19561 ttcactgtac tattatgaag atttaaatct aaaggagata ggaaaagtgc taggtgtttc
    19621 agaatcaaga gtttcacaac tccacagaaa atcaataaga aacttaagaa acaagataaa
    19681 agaacttaaa tattctatat agatggtgat tgataagatg atacaaatta tattaatagt
    19741 agtgtctatt ttaataatag taactatagt tataaattta cataaggaat caaaaaataa
    19801 agataacaga tactttgata aaatatttga gcaagaatat gaagcaaatg atagattaat
    19861 aattgcagaa aaaagaagat tctttttaga caaagtactt gcagaaaaaa gaagtaatag
    19921 tcatataaaa gtttatgaaa attataacct aataaaggct aatgaagaaa gaaaggaaaa
    19981 catatttata gaatcaaaaa aggaagtaag acaagaaaat gagttatctc ttaaagtgaa
    20041 acatcttata agttcaggtt atgatgatgt ggaaatatgt aagatgctag atattggaaa
    20101 gggggaactg ttattaataa ggagttgtta caaaatataa ggatattatt atgtgataaa
    20161 aaagtattct taggaatagg tattggtata ttaatatcaa ctttatgtat aatgcttttt
    20221 agtaataatg atatgagtaa ggcagagata gaaaaaaagg ccagagcgtt aggcatgaaa
    20281 tatacaagtg agatgaaagt tttagaatag atgatactgt ttaggcattt acaaaaaagg
    20341 aggtcataat gtgataagag gattatatac agcagtttct gctatgataa ctaatcaaca
    20401 aaagcaaaat gttgttgtca ataacctagc taatatggat acaaatggat ataaaagtaa
    20461 acaacttttg actaaaagtt ttgatgaatt aaagttggag ggttacaata actacgcaaa
    20521 tggaactaaa caaaagcaga ttataggcga tataagtcca ggtatttcta tggatgaaac
    20581 tatcacaaat tttaatcaag gacctataaa aactactgat aataaaatgg atgtagctat
    20641 tcaaggtaag ggattttttc tagttagtga tgcagctgga aatcaatttt acactagaaa
    20701 tgggaacttc agaacagaca atcaaggtga ccttataaca agtgaagggt attatgtact
    20761 tgggacgaat actgctactg gtgctgtagg tcatataaat gtaggaaatc aaaaatttga
    20821 agtggcaaaa gataatacaa tatcactaga cggaaatgct atgtataaat ttaatattgt
    20881 agattttaat aactacaata acttaaaaaa agaaggagat aacttatatt ctggaggagg
    20941 agctatgaaa gtaaataatg cacttacaat acaaagtgcg atagagtcct ctaatgtaga
    21001 tatggtatct gaaattaata atatgatgac aatatcaaga gaatatgagg caaatcaaaa
    21061 gataattcag gctatggatt ctaaattagc aaaaatagca agtgagattg gttcagtaag
    21121 ataggtaata ggaggtgaat ttttatgtac acaatgtttt atactagtaa aacagcttta
    21181 tcagcaaatc aaagtaaact agatataata tctaacaata tagcaaattc tgattcaaca
    21241 ggatataaaa aaataaatat ggaatattct gatttagtgg atgaagtact aaatagacca
    21301 tcatatccta caaatggcaa tgatatatcg actggaacag gagctaaggc aacagctccc
    21361 atgagaaatt atgaacaagg tgcattggct cctacagata gtaagagtaa tttggcaata
    21421 gatggagaag gattctttag agtgataaga aaagatggta catatgcata tacaagaaat
    21481 ggtggattta atgtagatgc tttaggtaag attgtagatg ataatggaaa tatattagat
    21541 gtccaatttg atgcaggata taactataat aatacaaata tagatagtac aaacctgaca
    21601 gtttcaagaa atggagagct attcgtagat aataaaaaaa taggaaaaat caacttatat
    21661 caacctatag gaactcaaaa ttttatatct gaaggagata gtttattcgt cgcaactgat
    21721 gcagcacaga ttaaacaagt tgagaaagtc gatatagttc aaggctatag agagaggtca
    21781 aatgtttctt tacaagaaga atttgttgac ttaatagcca ctcaaagagc atttcaaatg
    21841 aactcaaagg gaataaagac agcagatgaa atgtggcaaa tagcgaataa tttaagagct
    21901 aaataattat gtaaggtgag gaatattcat gaatgatatg aaagagtacg attttggcaa
    21961 acctcagagt tattcaagag aaaatttaac ttgtttaaat tttttattag ctgaattttg
    22021 taaaaaatat aaaaactata taatttatga acttaagtgt aattctagta tggttgttga
    22081 tagtatagac caagtaaatt atcagacttt tttagataga gtaacttctt catgcgtagt
    22141 agtacaaaat gcaatggaac ctgttatgaa aaacttttct tttagaatag atagaagtgt
    22201 agctgatatg tggattgata taacttctgg aggaactgga gttgtaaagg ataatgatag
    22261 agagcttaca gaacttgata aaaaagtgct tttacacctt atggatgatt tagtaagaaa
    22321 tatgcactta tttgagggtt ttgaaaatat acaagtattg gatacacata cacatattaa
    22381 tttgccacaa ttatgttctc caactgcacc agtatgcgtt gtagatttaa aagtgctaaa
    22441 tgataatgag tatattggaa gtgtttctct ttgctttcca tacaatggtt tagaggctct
    22501 gttagaaagt atatctgtta tagaattttt tgataatgat gtaggagatg attcagagga
    22561 atttacccaa aaaatctata atagtgtatc taatatagaa ttatcagtta ttgcagagat
    22621 aggaaaagta tcaattaatg ttgaggattt actcaaacta gaagttggag atgtaatagt
    22681 aacaaataaa aaaataaatg attatataga tatatttgta gaaaattcaa aatcatacac
    22741 agcaacacca ggatttatat caagtaaaaa aggtgtaaaa ataaatgatg ctgttggaaa
    22801 agaggtgtag ttatggacaa tagtaatctt atttcagatg aagaagcaaa gatgttatta
    22861 aatgataaag ttgaaagtga agttgatgga gatgatgagt tagccttaga tgtctctgaa
    22921 gttaatcgaa ataatataca aaggatactt gaccttaagt tagaattatc tgtagttata
    22981 ggaagaacta agatgactct aagagatatt ttaaatttac ataaaggttc tcttattgaa
    23041 ctggatactt tggcagacca agatgtggaa atactaatag ataataaggt tttggcttat
    23101 ggaaaagtag tggtggtaga tttaaatttt ggtgtaaaga taacaagtat agtaagtgaa
    23161 gaagacatgg taaaatctct tgtttagaga taacatcaat taatacttaa ggcatgaggt
    23221 ggtacttatt ttaaacttaa atgatataaa aaaagatata ctaaaactca ataaaaaaga
    23281 ctcatgttct ctatataatg aatctattaa taatataaat aataattgta tatcaactgg
    23341 attaaaattt ttaaaacaag caagagattt aaacccagat gatgttgata tattaaatct
    23401 cacaggtctt gtaaacttac taaaatgtaa ttttgatgat gctgtagaaa gtttctataa
    23461 gagttcactt tgtgaaaaaa ctgctctgtg tgaaaagtat ataaacatgc ttacatctga
    23521 ggagttttta attttctttg aaaagtacaa tcaacttata aggttaataa ataaaggaat
    23581 gtataaagaa gctatacaag ggtttaaact cataactgac caatactgtg atttaataga
    23641 accttatgag ttgcttgcct tactgtatga caaggaagaa gaatatataa aatttgatga
    23701 atgtttagaa gtattgaaga ttattgataa ggaaaattat ttattaaatc aagaaaataa
    23761 cacattagat atgtataata gtgctaatat acaaactaaa agtaatataa aagtagatga
    23821 ttataagaat gagtttttac ataaaagtag tagtaatcat aaaattaatg attataataa
    23881 tgtaactaaa gaaaagagtt caagcaaaaa ccagaaaagt tcagattcta ataagaaaaa
    23941 aagtattaaa aaaaataagt acctatatat agccataata ttaggaatat tattagtagg
    24001 acaaagtata tatagttctt ataagatgaa taatttaact gataaaatat ctaaaaataa
    24061 tgaaactaaa aatgaagagt caatagattc taacttgact aagaaagaaa ataatataga
    24121 agaaaatgaa gatatgagta aggcttctaa tataaataag agtaataaaa acattaataa
    24181 agaggatgat gtaaaatcta aaaaaaatac tgtagaaaat gaagatgata aagattctga
    24241 cttatttaca gaggatgaat tgatgtctaa ggcgaatact ttaaaatcag aaaagaaaac
    24301 taaatcttct atacaactat ataagaaagt tgcagatata ggtgaaaata aagggaatac
    24361 atctgaagca acttatcaag ttgctattct cagtgaaaag ttaaaagact ataaaactgc
    24421 tgaagaatat tataaaatgt atgtagaaaa ttactcagaa aaagatgctt attttgatga
    24481 atcttattat aatttaggta tgatgtacta taacaatggt gatttaaaaa attctaaatt
    24541 gacattaaag aagttggtta ataaggtacc aaatagtatg tataataatt caaaagtaaa
    24601 agaaatttta aaagaagaat agttaaatta gataagaaaa ataaattat
//
LOCUS       DAEPXW010000056        24544 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.057, whole genome shotgun sequence.
ACCESSION   DAEPXW010000056 DAEPXW010000000
VERSION     DAEPXW010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24544
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.057"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            59..1936
                     /locus_tag="KRM55_002297"
     CDS             59..1936
                     /locus_tag="KRM55_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1594536.1"
                     /translation="MVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLNTTLNYNQSTG
                     AYEGTINYNQDPEYLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIE
                     DITSRKDVNKYLRKTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGI
                     ISTPLATTYNAPILLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTV
                     NASQTRLNGSNRYETSLLIAKEIDKNHDVEKIYITNANGGEVDALTIAAKAGQDKQPI
                     ILTDKDSITDNTYKWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGAD
                     RHETNANVIKKFYTDNELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYH
                     KDNLEAKSANKVYKIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGS
                     APGNSSGGMIEKDYNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPD
                     LFTSIHYNGSTNKQGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRV
                     LPSDSTKDYLYVLRSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSL
                     K"
     gene            2178..4091
                     /locus_tag="KRM55_002298"
     CDS             2178..4091
                     /locus_tag="KRM55_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594537.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRVEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFVEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEIEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQDSILYSI
                     LLKISHKGDKNYD"
     gene            4084..6303
                     /locus_tag="KRM55_002299"
     CDS             4084..6303
                     /locus_tag="KRM55_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH1594538.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            6412..7242
                     /locus_tag="KRM55_002300"
     CDS             6412..7242
                     /locus_tag="KRM55_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBH1594539.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            7232..10699
                     /gene="addB"
                     /locus_tag="KRM55_002301"
     CDS             7232..10699
                     /gene="addB"
                     /locus_tag="KRM55_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBH1594540.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIINFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            10699..14526
                     /gene="addA"
                     /locus_tag="KRM55_002302"
     CDS             10699..14526
                     /gene="addA"
                     /locus_tag="KRM55_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBH1594541.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            14572..15783
                     /locus_tag="KRM55_002303"
     CDS             14572..15783
                     /locus_tag="KRM55_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBH1594542.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            15770..19297
                     /locus_tag="KRM55_002304"
     CDS             15770..19297
                     /locus_tag="KRM55_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1594543.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEIPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            19428..20681
                     /locus_tag="KRM55_002305"
     CDS             19428..20681
                     /locus_tag="KRM55_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH1594544.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            20830..21882
                     /gene="ytvI"
                     /locus_tag="KRM55_002306"
     CDS             20830..21882
                     /gene="ytvI"
                     /locus_tag="KRM55_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH1594545.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            21973..23199
                     /gene="pepT"
                     /locus_tag="KRM55_002307"
     CDS             21973..23199
                     /gene="pepT"
                     /locus_tag="KRM55_002307"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBH1594546.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPHLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            23406..24458
                     /locus_tag="KRM55_002308"
     CDS             23406..24458
                     /locus_tag="KRM55_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBH1594547.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVIEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
BASE COUNT        10485 a         2347 c         4373 g         7339 t
ORIGIN      
        1 tgaatctaat gctatggaaa ataacgctga tttaaatata aacttagaga aaaaaagtat
       61 cgttttaggt agcaaatcaa aagttagtgt caaatttaaa gaaaaaccag atgcagatag
      121 cattacatta aagtataaat gctatgacat gccattgaat acaactctaa attacaatca
      181 atcaactggg gcatatgaag gaactatcaa ttataaccaa gacccagaat atctaaatgt
      241 ttgggaacta caagggataa caataaacag caaaaataat cctaaaactt taaacagaca
      301 agacctagaa aagctgggat taaatttaaa agactataat gtaacacagg aatgtataat
      361 tgaagatata acttctagaa aagatgtaaa taaatatttg agaaaaactt cttcacctat
      421 tacagaactt acaggaagtg atagatatga aacagcagtt aaaataagta aagagggctg
      481 gaaaaatggt tcagataagg tagttataat aaatggggat gtaagtatag atggcattat
      541 atcaactcca ctggcaacca catataatgc accaatactt ttggttgaaa aaaacaatgt
      601 acctaatagt gtaaaatcag aattaaagcg cctaaaccct aaagatataa ttataattgg
      661 agatgagaat gctatttcta aaactactgc taatcaaatt aaatcaactg taaatgctag
      721 tcaaacacgt ttaaatggtt ctaatagata tgagacatct ttattgatag caaaggaaat
      781 agataaaaat catgatgtgg aaaaaatata cataacaaat gctaatggcg gagaagtgga
      841 tgcacttact atagcagcaa aagcaggtca agacaagcaa ccaattatat taactgataa
      901 agatagtatt acagacaata catataaatg gttaaagagt gaggatttac aaaatgctta
      961 ttttataggt ggtcctcaaa tgatatcaac aaatgttata aataaggtaa atggaataac
     1021 taaagatagt gttactaata atagagtata cggagcagat agacacgaaa caaatgcaaa
     1081 cgtaataaaa aaattctata cagataatga gttagaggct gttttagtag ctaaatcaga
     1141 tgtacttgtt gatgctttag cagcaggtcc attggctgcg aacttaaaat ctccaatact
     1201 tataacacca aagacgtatg tatctgcata ccataaagat aatttagaag ctaaatcagc
     1261 taataaggta tacaaaatag gaggaggatt gacttctaag gtaatgagct ctatagcatc
     1321 atcattatct aaacacaata cgactccaac agaaccagga aatagtgggg gcaagacagt
     1381 tatgattgac ccagggcatg gtggttcagc acctggaaat tcatctggag gaatgattga
     1441 aaaagattac aatttaaata cttcacttgc aacaactgaa tatttacgtt caaagggatt
     1501 caatgtaata atgacaagag acacagataa gactttatct cttggaaata gaactgctct
     1561 atctaattca ttgaaaccag atttatttac aagtatacat tataatggct caactaataa
     1621 acaaggtcat ggtgtagaag tattttataa gcttaaagat aaaaatggag ggactactaa
     1681 aactgtagct accaatatat taaatagaat tttagagaaa tttaaactta caaatagagg
     1741 tataaaaaca agagtacttc ctagtgattc tacaaaagat tatttatacg ttttaagaag
     1801 taatgatatg ccagctgtac ttgtagaatg tgcatttttg gataatgaaa atgatatgag
     1861 tttaataaac tcatctgcaa aagtaaaaga aatgggtaca caaataggta aaggaataga
     1921 agattcatta aaataaatgg aaataaaaat atttaaaaac ttaatgtaaa tttatagttg
     1981 taaatttata ctaaagtcaa aaaatgaaat ataagtgtat caatagtaag actgtatgta
     2041 catttgcaca tgtgaatgca agtatatata cagtcttttt ttgtagttaa atgcaataat
     2101 ttgattgtgt tttgtaaaat acacaatatg atataattag ataatataca cttaatttaa
     2161 ttgaggaagg tgattatatg gaatatttat ttgaaaaaag tagtttaaaa gaatatggaa
     2221 atgaagcttt agataaatat agagaattat tagataaaac tggtaataat tcaaggtgta
     2281 ttcttttgtt agtaccaaac aataacacaa agatacgata tgaaagggct ctaagattaa
     2341 attatagtga agaactgaaa ataacaacat atataagttt tgtgaagaaa gaattagtta
     2401 aatactggcc actaataata gaaaaatgtg atgaaataag tacaaaggtt gtatctccaa
     2461 catttatatc aaatagttta agtgaatatt taatagtgca aaaagttaag gaaaaaagga
     2521 tacaagaagg atattttgaa gatattacag gaaccaataa atccatagca aatagtataa
     2581 tgactaacat aaataagtct gcatttaatt taattgattt tgattttatt ggagaaaaaa
     2641 tatattcatc aaagaaaaat aaagatagta tatatagatt ttcatacact caaatggatg
     2701 aaattatatc atattatata aattccttac tatcaaattc aattttagat aatgcactaa
     2761 gcatatattt atacaatcaa tacctactta atgatgattt ttatttaaaa aacttattta
     2821 cagaagtgag atatataatt gtggatagcc ttgaaagctc aagtaatgca gaagttgatt
     2881 ttataacaga agcattggat aatacattac aaagttatat atattttgat tatagtaggg
     2941 attattctgt atttaataat gtggatatag actatataaa tgagaaaata atatcaaaaa
     3001 ttaagcctaa agaagaaaat attaaaaaga aggagattag agtagaagat ttatacttat
     3061 tacctgcaaa tatagaatta aatcaatcaa gtcaattata taatgaaatg ttagatttaa
     3121 taagtgaaaa agttatatct cttatagaag aagatgtatc tccaagagat atagcaatta
     3181 tatctcctat aaacaatagt atattggagc atcaaattag agattctttg atagaaaaaa
     3241 atatagatgt ttttagtact aagaaggata aaaaagctgt ggattatcca tatgggaatg
     3301 cattggtagt ggctacatgt atattctatg gatatttaga ttttataaaa gatgatgaat
     3361 acttaagctt tttagaaact cttttagaaa taaataggat aaaagcattt aagattttta
     3421 atgaaacaag acatttaagt attgataata tagatgaaca tagtcagtat cgtgatattt
     3481 tacagtatat tgaagaaaaa aagaagagtg atataaaaat acatgaattt ttaactcaat
     3541 tttacataga taaaatgtta aatttaaaag aaggtaaaaa gaatgttggg ttatgtaaaa
     3601 agataatagc tgaaagtgag tcttttagtg aaagtttaag tctacttggg atgaaaaaag
     3661 aaaagatatt tgtagaagct ttaaaaagta caataaacga ttattactct gttgtcgata
     3721 tagaagagtt gaaatccaaa gacaaaatag taataactac tccttattca tatatatcat
     3781 caaatataga tagaagtata caaatatggg tagatatagg aagtaatgct tggaatatga
     3841 aaatagaaaa agatataagt aatttaattg tacttagaaa atcttttgaa gaaaaaaaga
     3901 tttatacaaa tgaaatagaa gaatattata aaaaatacta tctatacaat acagtatata
     3961 atttgttatt aaatgcaaag aaaatctatg catttaaaag tgaatatgcg attaatggtt
     4021 atatccaaga tagtatatta tatagtatac ttttaaaaat ctcacataaa ggagataaaa
     4081 attatgatta atataaatta tagagaagac cagataccaa taataaatta cgataatggt
     4141 actatggcag taccagcagt accaggtgct ggaaaaacat ttataataac aaatttagtt
     4201 gctaaactat tacttgaaca gaaacataag ggtggtaaaa tattaattct tacatatatg
     4261 aatagtgctg taaataattt taaaggtaga ataagaaaga ttcttgaaga gaataaaata
     4321 gatgatacta attcgtatga agtaatgact atacacagtt tggctgtaaa aataataaag
     4381 gaaaagccag aagttgtaat gttaagtgag gattttaata tagctgatga tttgcaaaaa
     4441 agtattatat taaatgaatg tataagtaga tttagatttg aaggtggaga aagagctttt
     4501 agatggtttt taaaggagca aaaagatgaa cgctggaaag aaataactct tgaagcctgg
     4561 gaaagaggtt tttttgaatt tgcaggaaat gcaataagtg aacttaagta taagggaatt
     4621 tctccagata aacttgaaga aatattgtca agaggacaca aaggaatgct taaaattatt
     4681 ttaccaatat ataaattgta tgatagaaaa ttaaagcaaa atggattgct agattatgat
     4741 gatatattaa ttttagcaga aaaaacttta agcttagacg aagggcttag aaagaagttt
     4801 caaactagat acaaatatat atttgaagat gagtgtcagg actcaaatga aattcaaggt
     4861 aatataataa aaattatatc tagcgaaaat aaaaacctag ttagagttgg agatataaat
     4921 cagagtataa caggaacatt ttcatcatca gaccctaaat tttttaaaga atttataaat
     4981 agtgcagatt tctgttatag gatggatatg tcaaatcgaa gttcaaaaga tatacttgat
     5041 ttagcaaaca ctcttgtcaa gtatgttaca aaggaattta gacagaaaga atgtagacat
     5101 gctcttgaag atatgcaaat aaaaactgtg ccaaatggaa tgggatataa agaaaatcct
     5161 aatccagaac attataatat aaatgtaaag tggtatgaga gttggaaaat tgaaatagag
     5221 caaactgcta gatatgttaa aggtataaaa aataaatatc cagataaaag tataggtata
     5281 ttggttccat ttaatgaaca agtgacacaa gttgctaaag aacttagaga gaataatcta
     5341 acttttgaag aattaggacc aaattctttg aataaaagga aggttataaa caacatagca
     5401 tatattattg attttatgtt acattgtgat gatgtagaaa agttaatagt tgtacttaat
     5461 aaagttttta tagatactga taatgaagaa gaaataaagt attttttaga agaattaaaa
     5521 aactattcta ctgaagaaat tatttataat tttgaattta gtaagttaga taatgattta
     5581 atagaattta aagaagaaag tgacatatat ttaagtttta aaagaggaat agatattata
     5641 aaacagatat tagaatatcc aataataagg ttagacctct tagttttgtt tattgggaaa
     5701 aaacttaatt tagaaaaaga agataaagct gtactggatt atatatcttt ttatataaag
     5761 tatctagtat cagaaaatat aaatatggat ttagaagatg tatataattt attgtttgat
     5821 gtaaagaaca gggtgtttaa tcatataata gatgtggtat atgagataaa tggatatgaa
     5881 ccagagcccg gtagtataac actatgtaac tatcataaat caaaggggat ggaatgggat
     5941 tgtgtgtttt tactaggtct tgttgaatat aatttccctg acaatattaa tcaaaagttt
     6001 cagagtgata aatggtatct aaaagaaaaa tataaaaacc ctatggcaat tattaaatca
     6061 gaagttgaag ctatattaaa aggaagtatt tcaacagatt atgctcataa aacgaagatt
     6121 gattctataa atgaaaagat tagactttta tatgtaggga ttactagagc aaaggaaatg
     6181 ttagtacttt caggaagtgc ttatagagat gaaagtgata tagggaataa gagaaaagag
     6241 caaaaaccat gtatatattt aagcagactt aatcaacata ttattgaaaa aaggtcaaat
     6301 taatatataa taagttatta aaagattgct tgaaatatat ctaaaagggg ataaaacaat
     6361 atgtacagta agtaactact aaaaaataaa gttaagagag aagtgatatg agtgaacgat
     6421 aaattaaaat atttttctta tagtcaaaat tcaattaaca catataaatc atgtccattg
     6481 aaatttaaat ataaatatat tgatagaata aattggaaaa atgatgatgt tggtagtaga
     6541 gagtattatg aaactttaaa aacaggaaga gattttcatt tgatttgtga aagatatttt
     6601 agcaatatac ctcttggaat ctattttaat gaggatgata aaaatagtaa aaagttttta
     6661 aagtggatgg aaaatataaa aaaagttgtt cctattgaaa aaggaaaaac gtatttgcca
     6721 gaatatgaag taaggatgac attaaatggg gatataatac aggcaaagta tgatttagtt
     6781 gtaattggaa ataacaatat agaaatatgg gattggaaaa ccgagtctaa aaagattgac
     6841 tataaacacg tagaaaatag aatacaaact attgtttata tgtttttagc aaaagaagta
     6901 atacctaaag ttttaaaaat ggacataaat gttaaagata taaatatgag atattatcaa
     6961 cctgaatttg atgacttacc aattaccatt ttatatgatg aagaaaaaca tgaagcaaat
     7021 agaaataaaa ttcaaaatta tataagtatg ataaaaaaca ctaattatga agaacataca
     7081 tacgaagaca atctatacaa tgatatagaa aaggtatata ataaagaaga acgtatgtgc
     7141 tatagaaata aaaagcattg caagtattgt gaatttaata agttatgtaa tggcaaagaa
     7201 atagattata gtattttgga ggcggaaatt tatgggactt aggtttgtat taggtagaag
     7261 tggaagtgga aaatccacct atatactaga tgagattaaa aaagaagctc aaaaaaatga
     7321 aacgacatca attatacttt tagttccaga acagtacaca tttgaggctg aaaatagagt
     7381 aagtaagcta ttcttaggaa aagaaaaaga taagtatcta agagttaggg tacttagctt
     7441 taagacacta agtaatatag ttttttctca agtaggagga ttgacagatg taaatataaa
     7501 ttctagtgga aaagcaatga tggtatatag agctattgaa gatgtaagtg aagaattaaa
     7561 tgtgttttca aaatcaaaat cgcagtctgg ttttgtaagc tcaattacag atatgatatc
     7621 agaaatgaaa caatacaata taagccctga aatgttagaa aatatatctg gagaattgga
     7681 taatgaaact ttaagtttaa aattaaaaga tataagtaaa atatataatt cttttgaagg
     7741 gaaattgcat gaaaattatg tagatgctca agatatgtta acttcattgg caagtaaaat
     7801 tgaattaagc agttatttag atggagcttg tgtttatata gatgaattta caggttttac
     7861 accaaatcag tacaatgtca taaagagtat attaaataag tctaaaagtg ttaatatctc
     7921 tttgactgta gatgatatca actatattgg gtacagtaaa tctgatatgt tttctagaac
     7981 gaaatttact tattcaaaat tgactcaatt gtgcaacgaa gaaggcataa aaatattgcc
     8041 acaagtaaat ttaaacacag gtgttataaa aagatttgaa aaagttaagg aattacagca
     8101 cttagaaaga ttttataatg cttatccata taaaatatat tcaaatccaa ctgaaaatat
     8161 aaagataaaa gagtttaaca atttatattc agaggtggaa gagatagcca gagaaattgt
     8221 acatttagtt agagataaga atgtaagata tagagatata accattgcta caagagattt
     8281 aaatagatat gattttttag tacactctat atttaatgaa tataatatac caaactttat
     8341 agataagaag agagaggcaa aaagtaatcc aatagttatt ttaattattt cagctttaga
     8401 aatgaagaat agacgatatg ggtatgaaac tatgtttagg tatttaaaaa gtggacttat
     8461 aggaattgat aatgatgata taaatttact agaaaattat gtgttggcta atgggattaa
     8521 aggtaaaaaa tggtttgatg aaaaatggga ttatagaata acccaaagtc tttcaggtca
     8581 agaaagtgaa tttgaactgg aattaaaaga gaaaataaat gaaataaaaa atagagtatt
     8641 agagcctata gtaattttac aagaaaaatt aagaggaaaa aatagagtaa aagaaatctg
     8701 tagatatata tatgaatttt tattagatat aaatatgcca gaaactatag aaagtttaat
     8761 aataaatttt aaggataaag gggaacttga tgttgcaaat caatactcac aagtttggga
     8821 catagtagtg gacatattag accaaatggt ggaacttatg ggtgatgaaa taatttcttt
     8881 agaaaaattt ataaaattaa taaccttagg ttttgatgaa tatgaattag gactggttcc
     8941 tcctagtata gaccaggtac ttgtaagtag tgtggataga atgaaaaatc cagacacgaa
     9001 atatttatac ctagttggaa ctactgatgg tgtgtttccg ctgattacaa aggatagtgg
     9061 aatattgagt gataatgata gggaaagtct tggaaacaaa ggaatcgaag ttgatattga
     9121 tagtaagact aggagttttg aagaacagtt tcttgtatat aaagctctta cttcgacatc
     9181 taagaattta accataacat atccaatatc agaccatgaa ggtaaaacgc ttagaccatc
     9241 aataattata tcaagactta agaagatatt tccaaatata gaaaataaaa gttatttagt
     9301 ggaagaaaat aaaagcactg ataaagatat acttaaaaaa ataacggtta aatcccctac
     9361 atttaatgaa cttataaacg taataaaaaa ttatgacagt gatggttaca atacagaaga
     9421 gattaatagt atttggttag atatatatag gtactattta aaagatgaaa tctatagttc
     9481 tataacaaaa aaagttataa aaggtcttag ttatactaat caagttcata agattgaaga
     9541 gaaaaaaata aggtcattgt ataaaagtaa ttctcttagc atatctaggc ttgaaaaata
     9601 tgctgaatgt ccatttgctt attttataca atatggtcta aaagcaaaaa agcgtaaaga
     9661 gtattcattt acaccaccag atttaggaac ttttattcat aatattttag ataggttttc
     9721 aaaagaactt ttacaagata atttaacttg gagagatatt gatgaaaaat atatagaatt
     9781 aaagataggt ataatagttg atgaaataat tttaaagata ccaggatata tattaaatag
     9841 ttctgagagg tataaatacc ttgcatatag attaaagaat atgttgacaa ctgctataac
     9901 tataattagt cagcaaataa aacaaggttc atttgaacca atagattatg aagttaaatt
     9961 tggcaacaat ggaaaatatc cacctataaa aatggtgtta gaaaatggac aagaagtaag
    10021 tttaattgga caaatagata gagttgatga atttgaagaa ggagaaaata aatatataag
    10081 aataatagat tataagtcag gcaataagtc cataagtcta acagaaatat attatggtct
    10141 acaattacaa ttacttgtgt atttagatgc aatccttgaa agtgcaaagg atgaagatat
    10201 aaatataaat ccagctgcaa tactatattg tagaataaat aatccaatag caaaatttaa
    10261 tgaagataaa gatgatgaag aaatacaaga agcaatatta aaagaactta gaatgaaggg
    10321 gcttgtagta aaagactctc acatagttaa agagatggat aaatcattaa tagatggaga
    10381 aaggaaaaac tctttagtaa taccagtagg tcttactaag gatggaaatg taggtaaaag
    10441 tacttcagca ataagctatg aggatttcaa actgcttaga aaatatgtaa ggcatgctat
    10501 aaaggattta tgtgaagaaa tgttaagtgg agaaatacgt atagctccat ataaacataa
    10561 agatggaaca tcatgtgact tttgtgatta ctctgctata tgtcagtttg attcaactat
    10621 aaaagataac aagtataaaa atttaaataa taagagtaat gaagagataa taaaaatgat
    10681 gaaaggagat gttaattagt gagttctcct aaatggacaa aagagcaatt agaagttata
    10741 gaaagtagag aatgcaattt attggttgct gctgctgctg gttcaggaaa aacagccgtg
    10801 ctagttgagc gtataattca aatgataaca agtagagaaa atccaattga tatagataag
    10861 ttattagttg ttacatttac taatgctgct gcgtcagaaa tgagagagag gataggggat
    10921 gctataggaa aagccttaga tgaaaaccca gaaaataaac atttacaaaa ccaacttgtt
    10981 ttattaaata aatctagtat tacaacaata cactcattct gtttggatgt tataaaatca
    11041 aactttcata gaataaactt agaccctaat ttcagaatag gagaccaaac tgaatgtgct
    11101 attttgaaac aagaagcaat agaggaagta tttgaagatt tatatgaaga aagagatgag
    11161 gggtttttaa atttagttga aagttatgca gaaagaggag gagataaaga agtacaagat
    11221 attatcttgg gaatatattc atttgcaatg gcttctcctg aacctaaaaa atggttgatt
    11281 gactcagcag aacgatttaa tattgatgaa aattttgatt tttcacagtc tatttgggct
    11341 agagctatat tagatactgt aaaaatagag attaatggtc tttgtctaaa tatggaaagg
    11401 gcattaaaag aagtggaatc aatagaagaa ttagaaactt ttgcagaaaa gttatccgtt
    11461 gaatataaaa aaattgctga catttcacaa gcatgtaata aatcttggga tgaggcatat
    11521 aaaaagatgg caagtatgtc ctttgaaaat tatgtaaaag gagtaaaaag aatttcaaaa
    11581 gatgctcctt cgtatataaa agaatcaaaa gaaaaggcaa aaactataag agataagact
    11641 aagaaatctt tagaaagtat agtaagtgct acattcaata aagataatga ttctattaga
    11701 gaagaaataa aatatcttta taacatagtt aaaccaatat ctagtgttgt actgagattt
    11761 gaagaggaat atagcaataa gaaaagagaa aaaggaataa tagattttaa cgatatagag
    11821 cattttgcat taaatatact tacagatgta gatgaaaaag gtaatattgt accttctgat
    11881 atagcagttg gatatagaaa caagttttat gaaatattta tagatgaata tcaggatagt
    11941 aatctagtgc aggaagtact gcttaaagct gttgcaaata cagaaactcc aaatagattt
    12001 atggttggtg atgtaaaaca gagtatatat agatttagac aagcaaagcc agaattattt
    12061 ttgcaaaaat ataataacta taatgataaa aagggaagtt cccatagaaa aataatgctt
    12121 tacaaaaatt ttagaagtag agaagaagtt gtagatgctg taaattatat atttgaaaat
    12181 ataatgaatg agaatatagg agaaattgaa tatacagaaa aagaaagact aaatttaggt
    12241 gcaaatttta atgtggatac agacgagaaa tctattattg gtggagcaac ggagatacac
    12301 ctaatacaaa aagataataa acttgatgat gatattataa atgataaaga cgatagaatt
    12361 aataacaaag aaaatgaaat agaggaagaa gaaaaattag ataatataca acttgaggct
    12421 agaatggttg gaaacattat caaagattta atgaaagtca atgaagatgg aaaaattcaa
    12481 aaggtctatg ataagggaat agatggatat agacctgtgg aatttagaga tatagttatt
    12541 cttttaagag ctacatctgc atgggctcca gtgtttgcag atgaattgat gaatatggat
    12601 ataccaacat atgctgatgt tggagtgggg tattttgata cgattgaaat aaaaacaata
    12661 ttgtcattac ttcaaataat agataatcca atgcaagata tacctcttat atctgtatta
    12721 aaatcaccta tatttggatt tacaccagag gatttgattg atattagagt tcagagtaaa
    12781 gataaaattt tttatgaggt tttaaaaagt acagcagagt atgatggatt tacagattct
    12841 caaaatgaaa atgagtctga gtttatacca agtgaagagt gcataaacaa aagtaaagat
    12901 tttttaatta agctaaagga atttaaagaa aagtcaatgt acatgagtac agatgaattt
    12961 atatggtact tgtacacaag gactggatac tatgcctatg ttggagcatt gccaggtgga
    13021 agtcaaagac aagctaattt aaaagtattg tttgagagag caaaacaatt tgaagaaacc
    13081 agtcttaaag gaatattcaa ctttgtaaat tttatagaga aattaaaaaa atctagttct
    13141 gatatgggaa gtgcaaaaac acttggtgag aatgcaaatg ttgttagaat aatgagtatt
    13201 cataaaagta aaggtctaga atttccagta gtcatatgct ctgcaatggg taaaaatttc
    13261 aatactcaag attttaaaaa gagtatttta tatcatcata atttagggta tggacctcaa
    13321 tttgtagact atgagagaag gatttctttt ccaagtatag ccaaagaagc attaaaaagc
    13381 aaaataaata tagaaaattt atcagaagag atgagagttt tatatgttgc atttacaaga
    13441 gctaaagaaa aattgattat aactggttct actagaaata tacaagatag tataaagaga
    13501 tggtcaaatg gaattgaaag tttagataca atatcacaat acgagatatt aaaaggtaaa
    13561 aattttttag attggataat gccttgtgta ttaagacata gggatttatc taatctacta
    13621 gaagaagtag gattagacgc agtttttaat gttgaacata attcaaaatg gtatggaaag
    13681 ttgtggaata agaatgatat tttagtggaa aagaagagtg atgaagaaaa agaaagtatt
    13741 gaagaaattc ttgaaaaaat agatgtagat aatcctgaca gtgattatta cagtgaaata
    13801 gaagaaaaat taaactatat atatccatat gaatttagta caagaaaacc tgctactata
    13861 tctgttacag aaataaaaaa gatacaaaat aattatgaag aagagttaat aaatactata
    13921 tttgaacaaa aagtaatatt aaaaaagcct ctatttattc aaaatgaaga agaaagagaa
    13981 aaaataagtg gaacagaaag aggtacaata gtccatttag ttatggaggt tttagactta
    14041 aaaaatgtaa gtagtgtaaa tgatataaaa tcacaaataa gaggttttgt ttcaaaaggt
    14101 ataataacag aaaaacaagc tagtatagta aatccatata aaatatataa attttttgcc
    14161 tctaacatag gaaaaagaat gttgaatgct gaaattataa atagagaaaa atcaatttat
    14221 gcacaagtaa atatgaaaga catatatatt tatgaaaagc ttataaacaa tgatgataaa
    14281 aaactttatg ataatgaaag tgtcatgtta agaggtatag ttgatgctta ttttgaagaa
    14341 gataatcaaa tagttttggt ggattataaa acagattttg taaatgagga aaatataaat
    14401 caaataatag agaaatataa aaaacagttg gatttatatg cagatattat tgaaacttta
    14461 actggtaagt cagtaaaaga gaaatgtata tatttatttg gagttgatga agctgtttgt
    14521 tattagtttt tatatataaa ttaaacctaa aagatagagg aaggggaaaa aatgagattt
    14581 attcatacat cagattggca tctagggaag tccctagaag gccattctag aattgaggaa
    14641 caagcaaagt tttgtgagga atttataaaa atagtagaat caaatgaaat agatatggtt
    14701 ataattgctg gagatgtata tgatacttct aatccaccag cacaagcaga aaaactattt
    14761 tatcagactg tatcaagact tgccaataat ggtcagaggt gtgtattaat aatttcagga
    14821 aatcatgata atccagagag actctctgca ataacacctc tagcacatga acagggaata
    14881 cttatatatg gttatccatt aagtgctacg atagaagcta agtataaagg gtttgaaata
    14941 acatatgcaa ctcagggatg tacaaaactg aatataaatg gagaaaatat tgtggttgct
    15001 acattacctt atccaagtga aaaaagatta aatgaagttt tttcaagtga agatgagttt
    15061 gagaaacaaa aaaattattc tgaaaaggta ggagatatat ttagaagttt agaagaaaat
    15121 tttagaagtg atactataaa tatagccgta tcacatatat ttgtaatagg tggagagagt
    15181 actgaatcag aaagacctat acaattaggt ggaagttttt tagttgaaag aaaagatttg
    15241 ccagaaaagg ctcaatatac tgcactaggt catttacata aacaacaaaa agcttccgaa
    15301 cgtttaaatg catactattc tggttctcca cttcaatata gcaaggatga aagagcgtat
    15361 accaaagggg catacatagt ggatataaaa gctggtgaaa aaccaataat tgaagatgta
    15421 tattttaata attacaaacc tatagaagta tttaaatgta atggaataga agaagcacta
    15481 gatatatgtg agcaaaatca agatagagag atttggtcat attttgaaat aaatactgat
    15541 gagataatat cacagaatga aattaaaaaa atgaaggaac tattaaaaga cataatagaa
    15601 ataaaaccaa taataacatc ttgttatgaa caagaaagtg tagatataaa agaaaagtct
    15661 atggcagagt tgtttagaga gttctattct tttagtaaag gtgtagagcc aaaaggagaa
    15721 cttatggatt tatttctaga tataataagt gaagaaggtg aatcagcaga tgagaccaat
    15781 tagattagaa cttacagggc ttaatagcta tattgataaa caagttatag actttgaaaa
    15841 attaattgaa agaggtttgt ttgggatatt tggaactact ggaagtggaa aatctacaat
    15901 cttagatgca ataactattg ctatgtatgg aaatatatcc agaaatacaa aagaatatat
    15961 aaacagtgtg tgcgataagg caattatatc atacgagttt gagataggaa gcaaaaacac
    16021 tagaagaaga tacattgtag atagaaccat tgctagaagc aaaacaggaa caaagacctc
    16081 taatgctaga ttaatagaag tattgaatga caatacccaa aatgttttag ctgataaagt
    16141 tgtggaagta aatgaaaaag tagcgcaggt cgtaggatta acggcaaatg attttactag
    16201 gtcagtagtt ttaccacaag acaaatttaa tgagtttcta agattatcac gtgcagatag
    16261 aagagacatg ttagagagaa tttttaatct tgagaaatat ggaagaagtc ttggcgaaaa
    16321 agtgaaaaag agaaaaaata tacagttaca aaatttaaaa gatttgaaat caaaattaag
    16381 tcaatatgat ggaattacag aggaagtata taacaatata aaccaagaat taatagagtt
    16441 aaaaaatttg gaaaaagata agaataatgc tttagaccta gctcaaaaat cttatgaaga
    16501 aagtaaaaca gtatatgaag aacaattaaa gttagaaaaa aatgaactta gaaaaaatga
    16561 gcttgattta aaaaatagtg agataaaaga aaagattgct cttgtagaaa atgatagtaa
    16621 cgctaaaaag gtagacccat acataagttc agttcaaaat ctagaaaaaa agatagatga
    16681 agatagcttc gcagtaagta atttagaaaa gaaattagca atattaaatc aggagcttga
    16741 agttacaaaa aatagatatg aaaaaataaa caaaattaag aatgaagaaa tccctaaatt
    16801 gagtgaagaa aaaataagat tgcaacaagc aataaaatta gaagaagagt tagttttatt
    16861 agatagagag ttaaaagagc taaaagaaag tggaattaat ttaaataaga ctaaagttga
    16921 attagaaaaa gtaaagcagg tgtcagagtc cagaaaagat gcagttacta aatctataaa
    16981 agaagttgaa ggaaagattg ataaagtaaa tataagtgca gaattaaaac aaaaaatatt
    17041 tctagcatat gaatacgaga aagattacaa caacgtattg gaagaaaaaa atcaaaagct
    17101 aaataaacta gaagaaatac tcaaagagac agaaaatata aatttaaaag ttagatatat
    17161 tgataaagat aagaatgatg taaatcgtaa tttagaaaat ttatcacttc acttggatgt
    17221 tcttcttaaa aaatgtcctg gtaagagtgc tgatttactt ttaaaatctg aatatgttac
    17281 tgaattaaga aataaagcaa ataatactaa agaaaatgaa attaagaaaa gcagtataca
    17341 agatgaatta aagataatac ttgaaagtaa gtttaatact gaaagggaag taaatttact
    17401 aaatgaaaaa cttgaaaata atagaaagaa cagagatgac ctagaaaaag aattagaaga
    17461 actaaagtat ttaaatttag cctctgaact tagacgtgaa ttaaaagaaa atatgccttg
    17521 tccagtttgt gggtcaaaac atcatgaaaa tcataatata actaaatatg atgaaaatat
    17581 atcttttgtc aaagaaaaac tggagaaatt agaaaaagaa aaaataagta taagaaacaa
    17641 tatagaggaa ttaaatgcta aagtaagtgg gtatttatct atagaaaaaa tgaagactaa
    17701 agaacttgaa gatgtaaaag gaaaactagg ggggattcca tctagtcaat tattaaaaaa
    17761 acttgatgaa gaacaaagaa aacttgcatt gttaaaatct aatattcagg agtgggagaa
    17821 agaaaaagag agtactgaaa ataaagtaac attagcgaaa gaagaaaaaa ataaaattga
    17881 aaaagaagaa ttaaaaataa gagagagtct gaataattat aagaaattaa caagagattt
    17941 aaacatagaa atagaaggtt tagaaaataa atgtaaaaaa cttaaacagg aatacctagg
    18001 attaaagacg attactaaag tctctaatct attgtcaaaa gtaaaagaaa taagagagaa
    18061 tgaaaaagaa ttagaattac taagtactgg gcattcaaat ttattaaaaa atagagactc
    18121 actagatatt aaaataagag aaaatgagag taaactacat gaaatagaga tagaattaat
    18181 aaaggctaga gaattatatg tagaaaagaa attgagtagg gataataagt ataaagaagt
    18241 tattagcata actaaaggtg atttagctaa aaatctttta cataatgttg aagaaaatat
    18301 atgtaagata ttagaacaag aagaatcaag taagaaaaaa ttggaagagc aaagattaga
    18361 atatgaaaaa aacattgctg aaaagcacaa tatagatggt agacttaaaa ctgctaagga
    18421 acaatataaa gaccaaaaat caacactaaa taaactatta gcagaaaata aatttgaaag
    18481 tatatatgca gtaaaaagag ctttattaga tactgatgca gtaaaaaaat tgattgaaga
    18541 aatactagag catgaagaag aacaaaagtt attatcattt aaaataaaat catcaaaaga
    18601 aaaattaaat ggaagaagca taaagaagga gtactttgaa cagttaaaag atgaaattta
    18661 taatttgaaa gtagaaatag gaaatatatc caaagatatt ggagctaatc aaaatcagtt
    18721 aataacatta aaagactctt tagataagat aaatgatttt aataaacaac ttaaggtagt
    18781 tgaacacaat gtggacttat tggaagaatt agataaatgt gtacaaggaa ataaatttgt
    18841 agaatatgtt tctacaaacc aattaaaata tatagcgttg gaagcatcaa aacgattgga
    18901 tggaataaca aaaggaagat atgcacttga aattgactca acactaaact ttgtaatgag
    18961 agataacttt aatggaggag aaagaagaag cattgatact ctatctggtg gagagacatt
    19021 cttgacatct ctatcattag cacttgctct ttcatctcaa atacaattaa agggaagtgc
    19081 accattagaa tttttctttt tagatgaagg ttttggttca ttagatagtg aacttttaga
    19141 aattgttata gaatcattgg aaagattgca tagtaataat ctaagtgtgg gtataataag
    19201 tcatgtcgag gaacttaaaa atagagttcc tgttaagcta ttagtttcat ctagtgaggc
    19261 tggaataggt tcaaaagtaa aaattgaata tagttagaaa atatatgtta attgaatata
    19321 ttatctaata tttccaaata atatgtaatt gtgatataat aaaaactaat attaaagtta
    19381 tttataatta atattaatat aaaaacatgt aagtaggagt gtggtaagtg ttggaatcgc
    19441 ccaataattt gattcagatt atttttttaa tagtattact tatagggtct gcatttttct
    19501 cagcatctga aacggcctta atgtcgttga gtaaaatcag aatcagatat atgcaagatg
    19561 aaggagttaa aggagctaag ttagtaagtt cattaataga aaatccaaat aagcttttaa
    19621 gttctatatt ggttggaaat aacgtcgtaa atatagcagc aacatccata tcaacatctt
    19681 tgtttatagg attaatggga gaaaaaggag tggcacttgc tacagctgtt atgacagtat
    19741 tagtattaat atttggtgag attactccaa aaacaatagc agcaaataat tcagaaaagg
    19801 tttctctatt agtatctaaa cctataaaag caattatatt tatattaaga ccaatagtat
    19861 ggatatttaa tataattaca aatattatat ttaaattatt tggtataaca aataaaggag
    19921 ctaaatcatt cataactgaa gaagagctaa aaactatggt aaatgtaagt catgaagaag
    19981 gcgtccttga aatggaagag agagaaatca taaataatgt ttttgaattt ggagatatgc
    20041 aagctaaaaa tgcaatggta caaagaatag atatggtagc tatagatatg gaagatagtt
    20101 atgatgagat aatacaggta tttaaaactg aaaaattaag tagaatgcct gtgtatgaag
    20161 aaactataga tgatattgta ggaatactta atataaaaga tattatattt ttatctgatg
    20221 aagaaataga gtcatttgat attaaaaatt atatgagaga accttttttc acgtatgagt
    20281 tcaaaaagat aacacaactt cttgaagaga tgaaacttga aaaaagtcag atggctatag
    20341 ttgtagatga gtatggtgga acatctggac ttttaactat agaagattta gtagaagtca
    20401 ttgttggaga tatagaggat gaatatgatg aagaagagga tgaaatacaa gttataaaag
    20461 aagatgagta tattgtagat ggaagtacta aaattggtga tgttaatgaa cttattggtg
    20521 taaacttgga atctgaggag tttgattcca taggaggttt tataattgga cacctaagca
    20581 gattgccaga agaaaatgaa gtaattgaag ttgataatat aagattttgt atagaaagta
    20641 tagaaaaaaa tagaattaaa aaaataagaa tatatacata atgtaataat gttcttaaat
    20701 ttattagaag tgtataaata taaaagatat cttttatatt tatacacttc tttttatttt
    20761 gtattcaaat aaaactagta tgaaatggac aaaataaaaa tataaattag aagaaaggag
    20821 atttttaaga tgagcatact agaaaataat tttttataca aattaaaaaa caacactatc
    20881 tttttttgta tatatacatt gttatttatt tttatttaca aagcgtttcc atacatagct
    20941 ccattttttc taggtgctat aatagcactt atgattaatc ctatatcaca aaagttagaa
    21001 aataagtttc gtataaataa aggtatctct actcttgttc taagttttct tgcagtggct
    21061 atagtcagta cagttactac aataatagta ataaattcaa tgaaagaatt aatgggattt
    21121 ttaaataata tatctgctaa tcctgaggat ataagtaata ctattatgta ttttttaaat
    21181 aaaataaatg actttatgaa atcatttcaa gaaatagcca attttgatgt agaacaatta
    21241 gtaaacaaat tcagtggtga agtaatgcaa attacaaaaa atcttcttac tagtatactt
    21301 ggattggcta cttctattcc atatattata atatttataa ttaccttgtt tattgctacg
    21361 tactttatag caaaagacct tgataagatt gaaaatagtt tttataatat gtttactgtt
    21421 gatgttagaa agaaggtaaa aaacgtaaag aaagaggcag ggctttcact tgttggatat
    21481 ataagggcct atacaatact tatggctata acattttttg caatctgggg aagttttgct
    21541 ttatttggat tgaaatacgg tctaatagta gggtttgtag gagctttaat ggatttaatt
    21601 ccattcctag gtataataac aatatatctt ccagtaattg tttattattt tcttataaaa
    21661 aattatttta tagctataag tatgactgtg atattttttg ttttgtcttt gattagagaa
    21721 atacttgaac ctaaactagt atcagtaaat gttggactaa atccattagc taccctagca
    21781 gcgattttta ttggaatcca agtaaaagga ataattggag taattttttg tttgggtttg
    21841 gtatgtatgc atgatatact taagaaggtg gatatttttt aattataata attgatagat
    21901 ttttttaaaa ataaaatttt attcacaggt aaataaaaaa atattaatct tattaagaaa
    21961 gagggtatat acgtgaaaca aaaagtagtg gaaagatttt taaaatatgt atcatttgat
    22021 acaacatcta attctcagtg tgagaactgt ccatcttcag aaggtcaaag agttttagct
    22081 aagtatatag ttgaagagct aaaaacaatg ggtgttgatg atgtgagttt agatgaaaat
    22141 agttatataa tggctacttt aaaaggaaat actgatggtg tggatactat aggattcata
    22201 tcacatttag atacaattga agatgttagt ggaaaagata ttaaaccaag aataatagaa
    22261 aattatgacg gaaaagacat agttttaaat gaagcgttaa atgttattac gtatgtaaag
    22321 gattctccag agttggaaga atttaaaggt gacgatttaa tagtcactga tggaacaact
    22381 ctacttggct ctgatgataa agctggtata gctgagatag tgactgcaat agagtatcta
    22441 ataaatcatc cagaaattaa gcatggagat ataaaaatag gatttacacc agatgaagaa
    22501 attggtagag gtgctgattt atttgatgtt gaaaaatttg gagcaaaata tgcatatact
    22561 ttagatggag gaatagttgg agaacttgaa tgtgaaaatt ttaatgctgc aaatgcaact
    22621 attactatac atggtagaaa tgttcatcca ggttcagcta aaaataaaat ggtaaatgct
    22681 atacatatag ctgctgaaat atcagaaatg ttcccagcag atgaaagacc agaaacaaca
    22741 gaaggatatg aaggattttg gcatttaaat tctataggtg gaaatgtcga gaatgtaagt
    22801 atggcttata ttattagaga ccattgtaaa gaaaaatttg aaaatagaaa atctattatg
    22861 atagagaata tagaaaaaat aaataagaaa tacgataata gagtggaatt ggatttaaaa
    22921 gactcttatt acaatatgaa agaaaagatt gagccagtta tgtttatagt tgatatagct
    22981 aaagaagcta tggaggaatt aggtataaaa ccacatttag ttcctgtaag aggtggtact
    23041 gatggagcaa gattatcttt taatggatta ccttgtccaa atatatttac tggtggatta
    23101 aacttccatg ggaaaaatga gtgtatacca gttagttcta tggagaaagc tactaaacta
    23161 attgtaagaa tagctgaaaa atatgctgaa agagtttagt taaaaggtat ttaaaaatta
    23221 agcatttaaa gttataatag ctatatcatt ctttataagt caagctgatt ataagcttgt
    23281 gttgtattta aaatggtata gctatttttg taattatttt tataaaagat aattattttt
    23341 agtttagggt atcaataaaa agtatgaata tcaataggta ttaacattta aaagggggaa
    23401 ttgtattgaa aattaaatct aaaaaaataa tagcatttgc actttcactt gggattatgt
    23461 tgccaagttg tgtatatgca gacactatta gtaaaaatca aaatgcacag gtagatatga
    23521 acaattatct tcaaggtaga aaatctccaa aggaggaaaa acttattggt gaagatagat
    23581 ttgatacagc gataaaaata tctcaaagtg gttggaataa tggttcagaa agggtgtttc
    23641 tagttaactc aaattcattg ccagatgcat tggcttcaac tcctttggca agtaaattgg
    23701 atgcaccaat actgcttaca aataaaaata gtataccata taatgtaata gaggaaataa
    23761 aaaggcttaa tccagcagaa gttattttaa ttggaagtga aggagctatt tcatcaagtg
    23821 taaaagaatc tcttgaagat atggaagtat tagtcagtag aatcggtgga gcagatagag
    23881 aagaaacatc tttacttctt actagacagc tagatgatac tggtgattta ggtgtctcaa
    23941 aagtggcagt ggttaatggg tataatggac tggcagatgc aacttcaata tcaagcccag
    24001 ctgcaagtga taatacagct ataatatata caggtaagga tagcataaga agtgaggcaa
    24061 agaattttat tacacaaaac tcaactaaga catacatagt aggtggggag tacagtataa
    24121 gtaaaaaact tgaaggacag ttagtaaact cagaaagact agcagggaca gatagaaaag
    24181 atactaatgc gaaagtttta gaaaagtttt atggaaaatc aagtaaggtt aataatatgt
    24241 attttgcaaa agatggaagt ggtagagaag ctgatttagt tgatgggctt gctgctggag
    24301 tattagcatc aaaaacaaag tcacctgtag tacttgcaag tggaagttta agtagtgcac
    24361 agaaaagttt tataaaaaaa gtaaaggctg ataaatttgt acaagttggt ggaggtaaaa
    24421 atagtaaacc atatgcagaa gcattagcct tacagtaata ttgtgtaaat caaaattaat
    24481 atataataat agcaagtaaa ccaagttgca cttcaatata tataataaaa taagtaaact
    24541 aagt
//
LOCUS       DAEPXW010000057        24162 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.058, whole genome shotgun sequence.
ACCESSION   DAEPXW010000057 DAEPXW010000000
VERSION     DAEPXW010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24162
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.058"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     regulatory      290..391
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            464..1807
                     /locus_tag="KRM55_002309"
     CDS             464..1807
                     /locus_tag="KRM55_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH1594548.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            1986..3350
                     /locus_tag="KRM55_002310"
     CDS             1986..3350
                     /locus_tag="KRM55_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1594549.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(3528..5393)
                     /locus_tag="KRM55_002311"
     CDS             complement(3528..5393)
                     /locus_tag="KRM55_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBH1594550.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(5629..6846)
                     /locus_tag="KRM55_002312"
     CDS             complement(5629..6846)
                     /locus_tag="KRM55_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1594551.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(7046..7909)
                     /gene="aroE"
                     /locus_tag="KRM55_002313"
     CDS             complement(7046..7909)
                     /gene="aroE"
                     /locus_tag="KRM55_002313"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH1594552.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(7991..9913)
                     /locus_tag="KRM55_002314"
     CDS             complement(7991..9913)
                     /locus_tag="KRM55_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1594553.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(9977..10825)
                     /locus_tag="KRM55_002315"
     CDS             complement(9977..10825)
                     /locus_tag="KRM55_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBH1594554.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            11238..12119
                     /locus_tag="KRM55_002316"
     CDS             11238..12119
                     /locus_tag="KRM55_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1594555.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(12327..13190)
                     /locus_tag="KRM55_002317"
     CDS             complement(12327..13190)
                     /locus_tag="KRM55_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBH1594556.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(13345..15279)
                     /locus_tag="KRM55_002318"
     CDS             complement(13345..15279)
                     /locus_tag="KRM55_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBH1594557.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(15391..16404)
                     /gene="galE"
                     /locus_tag="KRM55_002319"
     CDS             complement(15391..16404)
                     /gene="galE"
                     /locus_tag="KRM55_002319"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBH1594558.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(16428..17297)
                     /gene="galU"
                     /locus_tag="KRM55_002320"
     CDS             complement(16428..17297)
                     /gene="galU"
                     /locus_tag="KRM55_002320"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH1594559.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(17495..17815)
                     /locus_tag="KRM55_002321"
     CDS             complement(17495..17815)
                     /locus_tag="KRM55_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594560.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(17805..19796)
                     /locus_tag="KRM55_002322"
     CDS             complement(17805..19796)
                     /locus_tag="KRM55_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594561.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(19919..22462)
                     /locus_tag="KRM55_002323"
     CDS             complement(19919..22462)
                     /locus_tag="KRM55_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBH1594562.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(22740..23074)
                     /gene="rnpB"
                     /locus_tag="KRM55_002324"
     ncRNA           complement(22740..23074)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KRM55_002324"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            23206..23883
                     /gene="srtB"
                     /locus_tag="KRM55_002325"
     CDS             23206..23883
                     /gene="srtB"
                     /locus_tag="KRM55_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBH1594563.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(24043..24117)
                     /locus_tag="KRM55_002326"
     tRNA            complement(24043..24117)
                     /locus_tag="KRM55_002326"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24083..24085),aa:Thr,seq:tgt)
BASE COUNT         7730 a         4169 c         2715 g         9548 t
ORIGIN      
        1 tttttttaat atattaactt aatatacata tttgatatat taaaaagttt ttacgaaata
       61 tccatgtatt cagtactttt ataattatat cacaaactca tttataataa acttccatta
      121 atagtataaa acaagttaga ataattgaca ttatactcat acatattcaa ttattggaaa
      181 aagtaatttt tttcaataaa taaccttaat tttttataaa atcgacaaaa aaacgaataa
      241 ttttattata tttattgtaa ataatacaat attacgatat aatacaacag aaaaacaaat
      301 agaaaatgtt catataatat tagtaatacg gtctaatagt ttctacaaac tcaccttaaa
      361 tgggttttct atgaatagaa tgtcaactct gaatatatgt tctattctat ctatatgaat
      421 atatattttt ttgtttatat cttaaagttt tttggaggta aaaatggtac caaacactaa
      481 caatgtacaa ccaggtggaa ataattcatc attaagcttt ttagacaaaa tgtttaaatt
      541 tagcgaacgt ggctctagcc ttaaaacaga agtaataggt ggagttacta cattcttaac
      601 aatggcatac atagttttcg taaatccagc aatattatct gaagctggaa tggataaagc
      661 cgcccttata acagttacca tactagctac agccattggt acacttatat ttgcgatttt
      721 aggaaatgca ccatttgctc tagctcctgg tatgggatta aatgcatttt tcacatactc
      781 tttggttata ggtgcaggaa tcccatggca aacaggtctt ggggtagttt ttctatctgg
      841 atgtgtcttc tttacactcg cagtaacagg tcttcgaaag acaattgcag acgcaattcc
      901 tagagaattg gcagtagcat cttcagcagg tataggtctt ttccttgctt ttgttggttt
      961 aaaaaatatg ggtgttataa tagctaatcc agatactata gtttcacttg cagattttac
     1021 accaacagtt ttaatagccc tttttgctct tatcttaatg gcaatactag aatataaaaa
     1081 agttaaaggt ggaatattga taagtatagt agttgcaaca ataatatctg ttatatttgg
     1141 atttgtggag ttgccaacag caataatctc aacacctcct agtatagcac cagttgcttt
     1201 taaattagat attgtaggtg cattgaaatt ctcattaatt ggacctatat tctctttcat
     1261 gtttatagac atgtttgatt cattagcatt tcttattact tgttgtaaac aaatgggtct
     1321 tgaagatgag aatggtgaaa taaaagattt aggaagaatg ttatatgcag atgtttcttc
     1381 tactttaata ggctcattct taggaactag tactgttaca acatttggag aatctgcttc
     1441 tggtattgca gcaggtgcaa gaacaggact tgcttcaata gtaacagcag cattattctt
     1501 agctacactt atatttacac cattacttgg tatagttcct acttacgctg cagctcctgc
     1561 acttgtaatg gttggtgtgt ttatgtttga aagcataaaa cagattgatt ttgctgatag
     1621 caaaatagct gtacctgctt ttgttacagt tttattgatg cctttaactt atagtataag
     1681 tattggttta tgctttggat ttatttcata tataataatg catgtagtag ctaaagaaac
     1741 tgataaaatc agtattacac tttggattat aggtttactt gcagttgtaa acttagttct
     1801 aagttaatat ttttaaatag ttctaggtca atattttaaa ttatatagaa taaaatctta
     1861 tttattttaa atttataaat agcaaaatca ctttatatgt aaattgattt tgctattaac
     1921 tttgtataga aaatttatta tcataatata tagatataaa aatatataga aaaggagtgg
     1981 tgtttatgtc acaattactt ataaaaaatg catatctaat tactatgaat gcagatagag
     2041 aggtatatga aaatggaagc atacttattg aaaataatat tataaaagag gttggtaagt
     2101 ttgatattaa tattgtagat aaagatgcag agatatatga tgctaaagga aaaatactaa
     2161 tgccagggct agtcaatact catgttcact tatctcaaca attaggacgt ggtcttgcag
     2221 atgatgttgt acttttaact tggcttagag aaagaatttg gccatacgaa agtagcttca
     2281 attatgaaga ttccttgatt tcatctactg catgttgtgt tgaattgata aaatctggtg
     2341 tcactacatt tttagaatct ggtggtcaat atgtagatgc tatggttgaa gctgttgata
     2401 aaactggact tagagcctgt ttagctaaat cagttatgga tacaggagat ggtcttcctg
     2461 aggcatggca aaaaactact gatgaggaaa tcaacactca attagactta ttccataagt
     2521 ttaataatac atctaatgag agaattaaaa tatggtttgc attaagaact atttttaata
     2581 caactgaaga attacttgtt agaactaaag aactagctga taaatacaat acaggtatac
     2641 atatgcatat tgctgaaata gctgatgaaa tttcatttgt aaagcaaaac aatggagttg
     2701 gaacagttga ataccttgat aaactaggtg tattaggacc aaatctttta gctgctcata
     2761 cagtttggct tactcataag gaaattgatt tatttagatt acatgatgta aaagtttctc
     2821 atgacccagg ttcagctatg aaagtggttc tagggtttgc atcaattcct gaaatgttag
     2881 aaaaaggaat acctgtttca attggtactg atggagctcc ttcaaataat agaatggacc
     2941 ttatgaggga catgtatctt acatcactaa tacataaagg aagaacttta aacccaactg
     3001 tcgtaccagc tgaagaagtc ttagaaatgg ctactataaa tggagcaaaa tgtgctttac
     3061 tagaaaaaga aattggtagt cttgaagtag gaaaaaaagc tgatatgatt attctaaatc
     3121 cagatacaat tcattgttta ccaatgcata atccaattgg aaatatagtt tattctatga
     3181 ctagtgaaaa tgtagactct actatttgtg atggtaaatg gttgatgaag gaaagaaaag
     3241 tattagttgt agatgaatct gaattattaa ataaagttaa aaaacaagct tctaaaataa
     3301 aagataaagc agaagttaaa attccatcta aatttaaaat tataaaataa cataaatttc
     3361 aattgttttg taaatatgaa tatataaata tatttatata catcatatat acaaaacaat
     3421 tgttttttta ttttatattc attagcattg ctcataaaat acaccataat tccagaaaaa
     3481 ataaccaatc agttaggatt acatcatcta agcaatatat aaacgtctta gtttataagt
     3541 tttattctac tcttatctaa aaccatcttt aaagagtttt caactgtttc aattacatct
     3601 ttataactca agtacacatt tgcgtagata caatcttcat ataaattata ttcagttact
     3661 ctacaataca gcagttttcc tccatctaat aaattgctca aaatatagtt ttcttttctt
     3721 gggacatagc ctatcacata tccagtttca ccaactattt taatagcttt ttcatcatat
     3781 agattatctt tctctctagt taaatagtat atcttacttt tctccaattc tttttcaaga
     3841 tattctctat ttctaaacct tgaaccagca acagctattg aagtcaaata gatatcctta
     3901 ccatgttcat ctacttttat tttttcaata tttacaaatt ctttttttaa attattactt
     3961 tcatataata ctcttcttaa ttcatccttc aatataacat ttttttcttt ttcatacgct
     4021 tctttaacaa tttttaattc ttcaagagat agtttctctc tgtatctttt taagatattt
     4081 atggattctt ttcttacttc atttatattt ccaaatattc cttttaaaga tatattcttt
     4141 ccttcaggat atagtgattt acttccttta agcacaataa aaaataacat atcatcataa
     4201 tattcttgag tcaatttatc tttttctata tctttcattt ttccaattaa atcatctatt
     4261 ttaaacgtct cttcaaaaaa atttaataat tttaatctag aacttgtcgt tcccttttta
     4321 gatatatgcc aatatacctc aaaatctcta atatctctat ttagatatgg caacaagtca
     4381 tcaaaagata agtttacatc ataaatttct gacattttta taatatcttc tgtttttcca
     4441 ctagcatctc ttaatgcttc aaaatatata tttttccatt tttcactgag caaaatacca
     4501 tttatttctt tttcaaattc aatcttattg cactctatat tttcatcttt taagacgttt
     4561 atagctatta ggaaaattga atataaactt tcaaagttag tcccataatt tactacagta
     4621 ggtaaaaatc gattcactaa ttctaattta ttacctatat atttaaattc tacacttagc
     4681 aagtaattgc atataagacg tgctaaatta tttatctttt ctttatctaa atctcgtttt
     4741 tcaagatatt cattcaaatc tacaattgaa ataatatagt tcatcaataa tcgttcgtac
     4801 tttgtatcct tataaccatc ttcaattaga taggaattta ttttagaatc taaattttcc
     4861 atattaacaa tagcaaatac ttttattgaa cctgtagcct ttttagataa attaaataaa
     4921 tatgtattgt aaaattcaag ttttttaata gtattactca gataaaatac gtattctcca
     4981 gatttagaaa atgtatctac aacttctctt aagttttcta catttagata tttctcactt
     5041 aaaactaacc ctagttttac atactcaact tttttactct tatatattaa ttctttagtt
     5101 aatttatata accatttctc atcaataatc atttctttta ccaaagtatt tatctttttc
     5161 ataaaaattt cgaaataaca aattaaagac ttagaattac taccctccaa taaataaatt
     5221 tcattagatt cacttttata catatttaaa atttcatcta ctagattatt tgcaagctct
     5281 acttgttctc ttaacggtat actttcatat atacataggt aattcatttc aaatgattct
     5341 ttgtatccat cataaccatt aaattcctgc aatcgcttaa aaacattctc caccaaatta
     5401 tcctccttta catgatgtaa tttatattga ttatactact tatttcatca agtttacatt
     5461 tatacgcaaa aaaatattac tagaaattga aattctagta atatccttat tattaattat
     5521 gtaaataccc tatcttataa ctgtaaataa tatccttatt aattttaatt acttttaata
     5581 aaaatctatc ctagatttag acttctctat gcatatatta tactaatatt agacatcata
     5641 atcatacact ttttcttttt catatctcat gtttacaaac aatgcaagta aaattccaac
     5701 aaatgttatt gccacattaa acaatacaac atattttggt ccattaactc cccctgattt
     5761 tgtaataata cctgctatat ttaaaataac atagtttgct atactagatg caatcataac
     5821 tatagatgtt atttttcctt tattagttgg aaacatttca tttgcagttg acgttgttaa
     5881 ctgaagaaca cctcctgctg ctgaataacc tattacaaat ccccctaaca tacaaatagt
     5941 tggagtttga acaaaatata caactaatag cataagtaaa gctattatag gatatataac
     6001 taatattctt attggtttaa tatatttttt aataagtaaa gaagttatta atactgcaca
     6061 tattactccc attgagtaaa aggattgaat ttttgtaggg tcagccatcc catacaattt
     6121 acccaattcc tgattacaat ttaaccataa tacaaatgta gatgtacatg taaatccaat
     6181 acaaacaaga gctatacttg ttggtgtaaa tttcatcttc tctgatttaa ctgttttgcc
     6241 tttgttatca ataacattat tagctggtgg aaatggtaac acagctatca aaaaggcatc
     6301 tactacaata agaatcgctg ttactataaa aataacttta aatgatattg aatttgctgc
     6361 aacaaatcca attataaaag gaagcaaaaa ttgtgctaaa gctattgtaa atttagtaaa
     6421 catatttgct attgttccta aactagcaaa tatctccata caagaaggag ttacacaggt
     6481 atctaagaat gaatttgctg cccctccaat tattgcaaat acatatgcta tataaaaatt
     6541 tggtgaaaat acaattccaa caaagaaaat tgcatgtaga aagtttccta taagaccact
     6601 tacttttctt ccatacttat ctgaaatagg tcctgcaaat ggataagata taagtctccc
     6661 taatcctagt gcagcaataa cagctaaaac aatacttaca tccaatgttc catctgataa
     6721 tgttttagcc ccccacattg atgaaaattc tggtttgtat tgtcctaaaa ttgaaattcc
     6781 aataccaagt aaaaaatatg aaaaatacaa cgctatggca gtaggataat attttttatt
     6841 gttcataatt tttctcccat tcttgttaat ttattaacat ttttgtgtac aataaactca
     6901 tccccataat ggatttaaag tatagtcagt taaaacttca aatttaactg gactatgagg
     6961 caaaacccac tatgacaatt tgtaatttat tattaaaaat attgaaatac gtatgttttt
     7021 tcattgttta agatattact cttatctatt taaagcataa ttcattaact tcttctacag
     7081 gcatttctaa tccagtatat agattaaaag cttctgctcc ttggtataat aacattccta
     7141 atccaccaat agccttacat ccattagctt cagcatcttc aatcattttt gttttcttag
     7201 gattataaac gacatctgtt actactaaat cttttcttaa aacactagta tcttttatat
     7261 ttgtttcatt gtcataaggc ttcataccaa taagagttgc atttgtcaat atatcacttg
     7321 attgtatctc ctcataaagt ttgtttgtat cttctaaatc atatagatta acaacacatt
     7381 ctggtacatc tttttttata ttctcaactg tttgctctgc tcttttataa aaatcatcct
     7441 taggattaaa gatagatatt tctcttgctc catctaaagc acattgtact tgtatagcag
     7501 ttgctgcacc accagcaccc ataattgtaa tctttttacc tttaacttct accccatttt
     7561 cttttaaatt acgaacatag cctactccat ctgttatatg accaactaac tttccattgt
     7621 catttacaat tgtattacat gctccaatta tacgagctgc tggagaaagt tcatccatat
     7681 attctgtaac agcagattta catggcatag taacattggc tccttttata ttaaaagttt
     7741 ttattgctaa aagtgcctct tttaccttat ctactgtgat atcaaaggct aaatatctat
     7801 aatctaaatc taatttctta aaactataat tatacatcac tggtgattta gagtgaccaa
     7861 ccggtgtacc tattaatgca aataatcctg ttctacctga aatttccata actataatct
     7921 cctctcaata ttatcatttt ctttgcaaat aacctattca gttatttaca aagaaaaatt
     7981 tatttattat ttatatattt aatgctactt caaaagcttc ttttgttgca tctaatgccc
     8041 tacgagcttt tactgcatca ccaacaatat aagtttcttt tacaacttct tttataactt
     8101 cacttaatgg gtcgtaatta cgagaaccca tagcaagtac tactgaatca aaacctttta
     8161 aatcatgctc tgtgccatct gtaagtaaat agtcgacacc atcatcataa aatttagaaa
     8221 cttttgcacc agtaatggta tgtatattat aattttcaaa atcattcata aggaatttac
     8281 ggtgttctga aattacatct gcaccaactt cttctctaag ctcaataaca gtaacctcat
     8341 gttcttgttc tccaaggaag gctgccactt cacatccaac cattccacct ccaacaacaa
     8401 gtactttttt cccacaagat tttttaccat caagaaggtc tacagcatga attaatcctg
     8461 aatcattgat tcctggtata ggaagtacaa gtggagttgc tccagtagct ataataacta
     8521 catcaggtga tttctccttt ataagttcta ctgtagcttc tgtattagta catattttta
     8581 caccatattg attacatttt gaaatataac ttctaactaa gttagtaata tctcctttcc
     8641 ctggaggata tgcagctaaa cgcatttgcc caccaagaac ttcagatttt tcaactaaag
     8701 ttacattatg tcctctttta gcacataccc atgctgcaag catacctcca acacctccac
     8761 caacaacaag aacttctttg ctaatttcag ctggcttaag ctctgcttca tgtcctaata
     8821 taggatttgc aagacaggct ataggtttgc cttggaacat atttggtaca catccttgta
     8881 agcatgcaat acatggtatc atttcgtcta gttttccatt tttagcttta ttaggcattt
     8941 ctgggtcagc caagctttgt ctaccgaatg ctactaaatc acatcttcct tgtctgacca
     9001 ttaactcagc aaactgtggc tctgtataac gtccaactgt tattactggt atactaacag
     9061 ctttttttat ttcagtaact aattctgcac tgaatccagc atgtaaagtc gtaggagccc
     9121 acatatattc atcatgtata tgtatactac gtgaaacatg aagtccatct attccacaat
     9181 cttctagata tgctgctatt actgaactat cgtgtacatc aattcctcct ggaacatcat
     9241 cagtgctgtt tatacgacat aatattgcta gagaatttcc tactttttta cgtatatttt
     9301 caatgataag acgaggtaat ctcattctat tttcaaaaca tccaccaaac tcatctacac
     9361 gcttatttgt tctttgtgat ataaaactac taaccagata tccatgagcg cagtgaactt
     9421 caacagcatc tgcaccagct ttttgtgcac gtaatgcagc atctccataa gattctataa
     9481 gttcatatat ttcttctgtt gttattgcta gtggtgtatt acgaccattt gatgcaggta
     9541 ttgcagaagc agcttttaat ggatgtcctg ctactttttc atttccttca gaaccagcat
     9601 gttgtaattg tatagatacc ttcgaacctg catcatgaca agcatctatt acatttttaa
     9661 aactatctat tgtgctatca tcatataaac aaggcttacg aggacctcct tttgcttttt
     9721 tgtctacaac actagattct atagttatta atccaaaacc acctaaagca cgctcaagat
     9781 aataagcctt agaagtttca cttaaagtac catctgtgtt tgcaaaattg tttcccatag
     9841 ggggaactac aaaacgattt ggaactgtca ttgaaccaat tcttataggt gtaaacatag
     9901 aactaatctt cataaggttt tccttccttt caagttttat attataatac tctgtatatt
     9961 tttatattat ataagtttat tttggagata cttcagacca tgctttatcc aaaacttttt
    10021 tagttgcatt aaatacagtt tcagcagcag tggataaccc tttagatatt agagaatcag
    10081 atattacttc tgcccctatg actcttggtg atatattgtg ttcttttatt attttcacaa
    10141 attcctctgt gtttccatat ccttcacctg gagccaaacg gtcatgtagt gattcatccc
    10201 taagtttttc ataaggagtt tctaaaacat cacacacttg aattgatact atcttatctg
    10261 ctggaacagg tgcaaggtcc tctgctgtct gctttgctct agcccagtgc caagtatcta
    10321 atataagcat tgcattttca cgattacatc ctttcacaac acgccatgca gtagccaaat
    10381 ctggtacacc actatatggc ataaactcaa gacctataat aagttcacct gctctgtcac
    10441 ataattctcc caatgcagtt ataatttgtt cttctggtat catctctaat aatccacaat
    10501 ttatatgttt aacattaaat aagtgagcca tatgataaac attttgctct ttttctcttt
    10561 gagcttccgt tctatcttct tctcttcccc attgagttat atattctact tctgtaactt
    10621 tcatatcata ttcattaaga attgcaatca tttcttcatc tgtaacacct gcattttttg
    10681 catcaatata attttcagca cgcaatccaa taccatcaaa cccagcttct tttgcaatac
    10741 gaactctatc acggaatgaa acttctgttc ccaatgtata agaactaatt gtaattggaa
    10801 tattaagatt tttttgatta ttcatagctt aaatttgccc cctttatttt ctttataatt
    10861 aatagtattt ttgattttat atttttattt atcctactag tagtattatt ttaccttaaa
    10921 aataaaagta ttttttgatt tctatttatc tagattttat aaatttattg tatcacgaga
    10981 ctttactaat aacaaattga taatttccta ttaattcata gattttgttt atagatttta
    11041 tttataagat aattcttgta tttttctatt aggtcgtata aatatattta tcttataatt
    11101 cagacaaaaa acgataaatt tttttaaaag cttttattct tactctataa tcatatataa
    11161 taaaaatgta aaaatatctt aaaggttaac ttctacaaat atataaataa aaatacctat
    11221 gaaaggatga acaaaaattg aatttatatc acttacgcta ttttgttaca ttggcacatt
    11281 tagaacacta tacaaaagcg gcagaaaatt tatctataac acaaccaagc ttaagtcatg
    11341 ctatttcttt actagaaaat gaacttgggg tggctctatt tgaaaaagaa ggtagaaata
    11401 tagtccttac taagtatgga aaaatatttt taaaagatgt ggaaaaatca ttagaaattt
    11461 tagattcaag tgtaaaatca ttaaaaataa ctggtactgg tgaaggacaa atagacttag
    11521 cttttcttag aacacttggt actgatttta tcccagacat agtgcacaaa tttttaaaat
    11581 ctaatcctgc taaatcaata gattttaaat ttcatactgg tgtaactact gacattattc
    11641 aaggtcttaa agaaagaaaa tatgatattg cattttgttc gaaacttgaa aaagaaaagg
    11701 gaattgaatt tatacctgtt gccaaacaag atttagtact aattgtacca tatagtcatc
    11761 cactagctgc aaaggatact atagatttaa aagaaaccat accttatcct caaatagtat
    11821 ttaatcagag aagtggtctt agatatataa ttgatgatat gtttaaaaaa ataaatcaac
    11881 agcctaatat agtctatgaa gtagaggaag accaagtaat tgctggatta gttgcaaaaa
    11941 atttcggaat tgctgtagtc ccaaatatga atatgcttag ctttacaaaa gtaaaagtaa
    12001 ttcagattat tcacccaagt tgggaaagaa acttttactt agcatttata aaagatagat
    12061 atttgcctcc tgcaattaaa aactttaaaa actttgtcat taaaaacgct caattataat
    12121 ttattaataa aggggttatt tttaaatatc ctcttttatt ctttttataa aataaaaaaa
    12181 tctatacttt taaaagtata gattcctaac tgacagtcgg catccgagtc tcagtaatta
    12241 tcgttataca acagcaactg gattcagttc ctgaataact aggttactta cattatatca
    12301 gattttttaa aatttgtcaa ttgtatctaa cgcatttttt caagccatgg tccaacaggc
    12361 tctacaatag gaacttcttt aaatccccaa tttcttatat cattcacact cgttggagta
    12421 tatattttgt ttctgacaga tttgaatatt ttgttttttt ctccatattg catacacttt
    12481 ggattagctt ctattaaccc tcttcttgct ctgctaagag gattacataa aatatctgct
    12541 atttctaaac cttctctata gtcagcatct tcttttttgg caattataaa acccttaacc
    12601 ttatctctta attcttcatc tatatctaag tatattgttc cattattaaa tacatcaaaa
    12661 aacgcctttt gtacttttaa gtttgagaca tcatcccttg actctataac tattcgtgca
    12721 gattctacag tttcattatt tacaaatgaa taaaaattct gaagaacatg tataaaagcc
    12781 acaacatacg gttcctttga aggtgcataa tatttcttta atctagcttt atctactgtt
    12841 actgatatta tagtacactc taatctagat agaaataaag gcaactcatc atagaataac
    12901 ttaatctgtg aatcatcaaa cttctcaaat gctcttgatt ttcttgatat atctgtcaaa
    12961 tgtattccta tgttactggt tccaaaacaa tactctttaa atgcatccat ttctttcctc
    13021 aaagaacata cataatcgcc ttgacttact gcatatttat attcaaaaat tactcctgtc
    13081 aatgtaaatg ggtcttcatg atttatatca gctcttccac tttcatcaat aaacattata
    13141 tattttttct ttataatctt actcaccctc ttaacatatg atgatagcat ctatattcat
    13201 tttatatgag ttttaaaaat attccaagat ttttatataa cttaaactta attttatact
    13261 aaaaaattga gatgtaaaac aatcaagctt ttattgattg aatttcacat ctcaattata
    13321 attatttttc aatatatatt tttactattt tgcaagaata tccattaatt tatccattac
    13381 tatataagat actccgcctc ctatttgata aggagtttca acttttttat ttgcaaatac
    13441 tctttgttgc tctgatgata atcctgaatt atccattaaa actattggtg aatgtaattt
    13501 tacagctaat ggtccagctg ataaagcatc tactaaagca tctgatttac taactaatac
    13561 agcctgtaaa tcagtatctc catagaattt ttctatcact ttggcattag tatctactct
    13621 actatctcca tatattctat ttcctgaaat atcttcagta gttatatcat tcatttttgc
    13681 tattactgaa tcgttaattg cacttggtcc acctataaag tatgcatttt ctaattttct
    13741 ttctgttagc catttataag attcttctgt aattccatct ttattgacta atattatagg
    13801 ttgtttttct tccccagctt tagaagctac agataaagca tctgcctccc catttccaga
    13861 aaccatatat gcagttttta tttcttctcg atttccaagt tcttcagcta ttcttgtagc
    13921 agtttgatat ctatcttgac ctgctattct ctttgtttct gtgttgaaag tagtttttat
    13981 ttcttgctct aatttagaac ttattgcatt ttctccacct atcaagatta ctgttttagg
    14041 tgctaataac ttcatttctt caacagtttc agttggtaaa ttagctgtat tagtaagtag
    14101 tattgttgag tcatagctac ttgctaaagg agttgctgtt ataccatcag ctattgcatt
    14161 accatttact aatattacag tatctgaact atcagcattc cagtttccaa ctgaacttat
    14221 ctttttagct gtatcaaatc tatttgcacc tataattgta tcccatgtag gatttatagt
    14281 tccatcttca ttaaaagtat aatctttccc atctattttt tgagaaccag ttagcatctt
    14341 tccatctttg tctaaatagt aagacttacc atctatttgt tgccatcctg tctgcattat
    14401 tcctgttttg tcaaagtaat acttattacc atctatttct tgccatcctg ttactgctaa
    14461 accatcagat cctagatagt atttctttcc attcttttct tgccatcctg tttgcattac
    14521 tccatctgag ttaaagtaat aagtttttcc gtctattact ttccatccag atactcttgc
    14581 tccatcagtt cctaaataat attttttgtt attaattgtt ttccatcctg tttgcattac
    14641 tcctgaagca tcaaagtaat acatttttcc atttactttt agccaactat tcttttggta
    14701 tgttccatca gattttacat aatacttctt accattttct gttttccatc ctgtttgatt
    14761 tagatttatc ttatattttg ccgctatctt tacatagctg tcgttactat aatctataat
    14821 tacatctgaa cctacaggaa cttggtcaaa taaccatcta acatctttat tgtgcattct
    14881 tatacatcca ccagaaatat gctttcctat agaactctca ttattatttc catgtattcc
    14941 atatgtatct ccataagttc cttttaatgc taatcccatc catctatctc ctaatggatt
    15001 tcttggactt cctccaggta tattaccttt ataatatggt ctatttttta tcttgttaac
    15061 tacttttgtt ttccctgttg gtgtttctga ccccttttta cctgttgcaa ctctaaattc
    15121 ttttacaagt ttattattta caaaatatcc tagagtattt tttcttgaat ttactataat
    15181 cacatgttta ctggctgcgc ttgattctgg tacgccacat gcaaatacta aaactaaagt
    15241 cagtgctagt actaaatact tttttagact ttttttcact ataacttccc cctcttttag
    15301 aaacattact acatgtgtct aattataaca taaaattacc aataccttat atttacaaat
    15361 ttgttacatt tatacatata agtatgtatt ctactcttca tacccattag gattcatact
    15421 ttgccatctc catgaatctt cacacatctc ttcaagttca tacttagctt tccatccaag
    15481 ctctttttct gcctttgaag aatctgcata acacatggct acatctccag cccttcttcc
    15541 tacaatctta tatggtattt cttttccact tgctttagaa aatgctttta ctaaatcaag
    15601 aacactatac ccctttccag ttcctaaatt ataaacaaca agtcctggat tttcttctaa
    15661 tttttgtaat gcttttacat gaccagcagc taaatctaat acatgtatat agtctctaac
    15721 tccagttcca tcatgtgttg gatagtcatt accataaaca ctcaattcct tcaatttacc
    15781 tactgctatt tttgttatat aaggcattag attgctcgga actccatttg gttcttcacc
    15841 tattctacca cttttatgag caccgactgg attaaagtat cttaaaagag ctatatccaa
    15901 tgacttatct gcttttgata tatctactaa catctgctct atcataagtt tagttcttcc
    15961 atatggattg gttacagaaa gtggaaaatc ctctaatata ggacaagtat gtgggtctcc
    16021 atatacagta gctgaagaac taaatacaaa ctttttaaca ccatattctc tcattaattc
    16081 aaataaattt aaggtactta ttagattatt gctgtaatat tcaattggtt tttctactga
    16141 ttcaccaact gcttttaaag ctgcaaagtg tataattgat tcaatattat tttctttaaa
    16201 tacaacatgc atttcatctt tatttctgat atcaatatta taaaatttta ctggtttttt
    16261 agataattcc ttgattctat caaccactat tgagttgcta ttacttaagt tatcaactat
    16321 aacaacttca taacctgatt ctaaaagttc tattgctgta tggcttccta tatatcctgc
    16381 tcctccagct actaaaactg ccattgtaat tacctctttt ctaatattta tttttcactt
    16441 actttttttc tcatatagtc cattaaatca tcttttaaat tttctctctt tagagcaaag
    16501 tctattgttg cctctaaaaa accaatttta tctcccacat catatcttct accttcaaag
    16561 ttataagcat aaatagcctc ttgttttcca agagtttgaa gtgcatctgt cagttgtatc
    16621 tctccacctt taccaggtgt ctgtttctct aatatgctaa atattgcagg agttattata
    16681 tatcttccaa gtatagctat atcagatgga gcttcttcaa ttgcaggttt ttcaaccata
    16741 tctttaactt tatatactct atcttcgata tgttttacat ccaatatacc atatttatta
    16801 gtatcttctt tagctatctt ttgaacacct aatacagttg ttttatactc attataagta
    16861 tctattaatt gttttaagca cggaacatct gaatctacta tatcatcacc taataatacg
    16921 gcaaaaggtt catcacctat aaaacttttt gcacagtaaa ttgcatgtcc aagacctttt
    16981 ggctcttttt gtcttatata atgaatattt accatatttg atatgtctct taccatttct
    17041 aacatctctg tcttaccttt ttgctctagt tctaactcta attcaactga tttatcaaaa
    17101 tgatcttcta tagatttttt atttctacct gttattataa gaatttcttc aattcccgat
    17161 tctatagctt cttctattat atactgtaaa gttggtttat ctactatagg aagcatttct
    17221 ttgggctgtg attttgttgc tggtaaaaat ctagttccta gccctgctgc tggtattatt
    17281 gcttttttaa ctgtcatctg cattttttca cccttcttcg taaattttct attgtaccaa
    17341 attaatatac catatttata ctttttcttc aaactctata ttatcccaat atttaatgct
    17401 ataagataat ataaggtaga tgaaatttca tctaccttta gttttataag ttaatattgt
    17461 attgtttata ttttatccaa aacttataca ggtactaaat ttcatctaag atgcctttta
    17521 tatcactatc tatatcttca tctagataag aatctaaatc ttctaagtca acttctagtt
    17581 cttgatatgt catatcaaca ctgacatcct catctatatc catttctgat attaattctc
    17641 ctaaaatact atttccatca gaatctaaac cactatctat atcttcatct atatagtttt
    17701 catttaaaat ttcatctaaa tcaatctcgt aataaacttc attatttttt tcatcccctg
    17761 agtccaatcc taagaactca tagttaaaag tccaaacatt gtatttactt gacatacttt
    17821 attcctcctg tgaaaaacat attttcatct agtttattgg ttccataatc aacagagtta
    17881 tatatttttt caattatgtc ttttcttctt tcttttgtac tattatttaa tgtcaattgt
    17941 ttaaatacat atgtatttgt tattctctcg aataatattt cttttatact atcatcatca
    18001 atatttctat agtttttcca caataactca aataacttaa acatttccct actagtttca
    18061 tctacataat aaggatacat attttctact aaatggttta atcttgatat ggcttgtttt
    18121 aaaaatacat caagacttgc actttcactt tcttttaaca ttctataatt gtatttcttc
    18181 ttatcttctc ctgaaattac aaagatgata ttgtctaaac ttttttcaac ttcatttaaa
    18241 taactgctta tattatatga taaatcagac aatagatttt taatctgctt aaacacttgt
    18301 acatcaagtt tagtattata cttttcaaac aaatctattt cttgattttc taatattctt
    18361 ggcatatatg ctgacaataa atctaaattg tttctttgtt cttgtatttg cttataaagt
    18421 gaatttataa cttctattct tatttcatca tttaactctt tttctaaaat cttatcaaat
    18481 tcagatttca tatagtaaat atttccaaag aaattaaata ttatcatatc attcatagct
    18541 ttagaccaat tcttatatat cacttcaata gaattttctt taagtagagg ttgctttgca
    18601 tatataaata catcttgcat aagtttttga accatacttt tacttaagtt taaaagtact
    18661 ttttgattat taaattttat ttccgtttct acaaaattag aattttcgtt ttcaagttct
    18721 ttattaatta caatgtcttt tatatcacta ttttttatag atatgatttc tttttgaaaa
    18781 gactttagaa tagtcaagct atcgaaatct tcttgaataa aaaatggagc atgttttaat
    18841 gtatatccca ctatttcatt ttctatatct tttaggtcat ctatttgcat aatttctcta
    18901 tttttatcat ttatatgtag gttaaataca tttttattat catataatat tatatcttct
    18961 cctaaattta acttagaaca attatctttc gctgacttta caatagtctt cttagatttc
    19021 ttatttataa aaattaattg gtcttgatat tttactaaaa gcatgtttgt gtttttataa
    19081 tcaaatccat ctatatttcc tgatatcttg cagaatacta tttcacaatc tttaggaaga
    19141 tttcctattt tttggttatc tttaactctc tcatttaaat cagatgggac tacactatct
    19201 atattgttat taaatataga tacagacctt actataatcc cctctctttc catatgaaag
    19261 tatcccttca atgacactct tttatcttct aaaatgtatc tttctatatc atcaaaattt
    19321 atttcaaatc tatttttccc actgataaat ataaacttct cattatcttt attaattcca
    19381 cccatataaa acttattgtc atctaaactt aatatagtca tattatcctt tagatagaat
    19441 ataaattctc tttgactttt gcagattaaa tcatattcat ccaaagttat tttcatagtc
    19501 aaatttgctg taacattttt acttgaattt tcacttttta tgtaaaaagg caagttattt
    19561 ccatagacaa ttatttgaga atcttctaaa actgcctcta atttttcttt attgtctgaa
    19621 aaactatata tatattttac acctgtatcc tcattaactt catctgattt gctgattatt
    19681 atattcccta gatttgttat atgaagcttt ttatattctt ttgagtatct acttatgcca
    19741 ctaagctcaa acccatctga aagctcatat atgatttttt ctcctaattt caacatacct
    19801 tcaccaccta aacagaatta taagtatttt ataaaggtga ataaaatgtc tcaaaacaaa
    19861 taatattttt tttaatactt tttattctga gacatagttt ctcctttttt ataatgctct
    19921 aagcaccttc aactatttct tcataaagtt tatctaaatg tttaacatat tcacgatatc
    19981 cagatttgtt ctttaactca cttcttaaat cttcatattt ttgtttaagt tcttcagcac
    20041 tcaaagaagg agctgattct tttaattctt ctaacttata atcatagtac ttatcataca
    20101 tagctatata tgtatcaata gacttcttag ctagttcatt acatttttct tgtgcttctc
    20161 catattgaga ataatcacct atttttattt tatagtatcc attttcttga attattgttg
    20221 aagaaatacc tttagcttca tattcttttg ctgtttcttt tgctgttttt tcaactttaa
    20281 gtgaacctgc ataaacagtg taatatacac ctttaccatc tttatatgct tccatttctt
    20341 ttgctttctt ttcagcttgt gctttttctt gagcctcttt ttcagctttt gccttttctt
    20401 ctgcttcttt tttctctttt tcagcttgtg cttttttctc ttcttcagtt aatttattgt
    20461 tagcttgttg ttgagttgat gactttggaa tattctcttt atcatttttc ttattgttgc
    20521 ctactgttat aaaatatcct acaccaacaa taaccactat aactactgct ataatagttt
    20581 cttttaatct actcttctta gaaacaacct cttcatcatc taaagaatct tctttatctg
    20641 atacataatt tttcatttct ttcttgtttt ctctatattt gtccttagaa gaatttttag
    20701 attttttatt actattttct ttctttttaa taggtattac tactgatttt tcattttcta
    20761 atttttcttc ttttatttct tttgcttttt tatcttctaa gtttttactt tctttttcaa
    20821 gcttcgattc attatttgaa gatacttttt catctaagtt attatttatt ggtttttcta
    20881 tttttacact acgttcttct tctatatgtt gacttggttc ttcttgtttt atttctttca
    20941 attcattttg ctctatttct tctgatttca cttgatgatt ttcaactggt ttatctaaaa
    21001 ttatatctgg agaaatatca tttaaattct cttcttcttg ttcagcttct tcattgtctt
    21061 ttttaataaa tccaaataat ttagccttct ttttactctt tttattttct ggttcaatta
    21121 tatcttcttt attgctgtcg tactctttat ctgtagtatc tttatcttct acaacgtcac
    21181 ctatatcttg attattacta tctacttctt ctttagtccc ttcttcagca tcatcttcta
    21241 ttgaaatact acttctaaag caaatatctt tatctgcatt ttttatcatg taaatgtatt
    21301 cttcaatatc gatatcttta tttcttctag ttctttttga tgcaatttca tgattttcta
    21361 attcactata gttatctttt attagattct gtgctttatt ccatgtatct tcactaattt
    21421 ctgttttatt tttaattaca tagtccacaa attccttaaa attttcagga ccaaattctc
    21481 caattatagt cagtctcatt gcaccttcta taaggtctct atttcttctc tttaaaaatt
    21541 ctaatacaac tgttgcacaa gcaaaatctt taataatttc tttgccaaaa ccatatgctt
    21601 caacagaatg aagttcttct aatccacata acttcttata ttcattgtgt attgtttgag
    21661 atatactttc attatttaag ctatttaact tatctataaa cttcgattct atatcatttg
    21721 attttgattc atgttttact tttgaatttt taatttcatt tagtagcatg tcattttctg
    21781 aattatcttt acctaattgc aaatcctcaa tttcagttgc ttttatttct actttgtttt
    21841 gttcgttatt ctcttccaca ttattaggta ccacatcttt attactagct aatattttgt
    21901 ttacacagaa tataatttct ctttttaatt ctcttttcgc atctgcttga tttttaagaa
    21961 ataaatctcc acattctttc ttttctaaac ttatttttct aagagatata ttaagaaggt
    22021 ctttatatag gtttaaaacc ttataatcct tttctaaacg tcttcttctc tctgatagtt
    22081 ccattttatc ataagctaaa aaactattta aatcattggc ttttagagag tctaatccct
    22141 ctttcatagc cttatttaca tactttctac attttgctgt agttaactct aaatcttttt
    22201 ctaattcatc tatttcaggt atgtacttat ctactatcca tttgccaata agtggttctg
    22261 tatttcttgc taatgtctta taaaacaata tattaaattt taaaagctct gcatattttg
    22321 cttcattaaa ttctactttt tcaaatttct tttccaaaac accatctagc ttttcattta
    22381 ttttagactc ttgttttaaa aaacttgctg tgacatttaa aacagtgttt cttattatat
    22441 tattttcact caaaaccttc actccttaaa tcaattattt tattgtaata tttacattgt
    22501 gcaaagttgc taatttgatt atgatatcta aataattatt tactaaattt gctacatctt
    22561 atatcatatc atattattta catcatttta ctttttcttt ttatatctat cttatattat
    22621 accattttta atatctgtac taacttatat tacaatattc ctcaaaattt taaaagtaga
    22681 ttagacaaat ttacaaataa aaaaacatca gtttaaactg atgtttttga ctatcgaaat
    22741 aattaagcaa gtctataagc ggagttctgt attagataat catctttcta ggcctattgt
    22801 caccaatagg ctcaagcgac ctacctaccg gagagtacga gcagcactct ttattcctat
    22861 cttggtcttg ctccaggtgg ggtttacata gccaactagt cgcctagctg ctggtgagct
    22921 cttacctcgc ctttccatcc ttaccacaat agtggcggtt tatttctgtt gcactatcct
    22981 taggatcgct cccactaggc gttacctagc accctgctct atggagctcc gactttcctc
    23041 atgtaagatt acatgcgatt atctggctta cttaatattt attttactta gttatgttaa
    23101 cacaaattct tttacatgtc aaagtaatat tatactaaaa atttaaattt attcaaaaat
    23161 agtgtaatat agatatataa actacattta actcgaggtg atctattgaa aaaattatat
    23221 agaatagtaa ttaacattat actagtatta gtaatacttt acagtggatt taatatatac
    23281 tcaaaactta ccaaatacaa tcatgatact aaaatatcct cagaacttca aaaaaaagaa
    23341 tataaaaaag aggatttatc aaagattaac agtgatttta aattttggct ttctgttgag
    23401 aatacaaata taaattatcc agttgtacaa tctaaagata attcttacta tcttgacaaa
    23461 gatttttata aaaaagattc tatttctggt acactgttta tggattatag aaataaatct
    23521 attgatgaca aaaatatcat aatatatgga cataatatga aaaataaaac tatgttcaac
    23581 aacctaaata agtttaaaga tgctgacttc tttaaaaaaa ataataaaat aaaaataacc
    23641 ttgaatggaa aagaattttt atatgatgtt ttttctgctt atattgtaga atctgattat
    23701 gattatctaa aaacaaattt taacaatgaa tctgattatc aaaattacat aaatgatatt
    23761 acttctaaat cattgtataa atctcctatt aaggtaaata gcaatgataa aatagttaca
    23821 ctttctacat gtacctatga atttgatgat gccagaatgg tgattcatgg tagattgatt
    23881 taaaactcac agacacagtt taaaacaata attttaaact gtgtcatctt ttatacctat
    23941 aatttgtaaa ttagaccact aaaagtattt aatacaaaat aacaaataca tcaaacaata
    24001 aaaaacaata aaaaaagact atgctaaaaa catagtcttt actggagctg gtgataggaa
    24061 tcgaacctac aacctgctga ttacaagtca gctgctctac cgttgagcca caccagcaca
    24121 cctattttat tgtaaattag caaaactaat ttttaaaagt ta
//
LOCUS       DAEPXW010000058        24139 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.059, whole genome shotgun sequence.
ACCESSION   DAEPXW010000058 DAEPXW010000000
VERSION     DAEPXW010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24139
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.059"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            200..646
                     /locus_tag="KRM55_002327"
     CDS             200..646
                     /locus_tag="KRM55_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594564.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVS"
     gene            1027..1944
                     /gene="pstC"
                     /locus_tag="KRM55_002328"
     CDS             1027..1944
                     /gene="pstC"
                     /locus_tag="KRM55_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBH1594565.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            1946..2770
                     /gene="pstA"
                     /locus_tag="KRM55_002329"
     CDS             1946..2770
                     /gene="pstA"
                     /locus_tag="KRM55_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBH1594566.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            2789..3553
                     /gene="pstB"
                     /locus_tag="KRM55_002330"
     CDS             2789..3553
                     /gene="pstB"
                     /locus_tag="KRM55_002330"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBH1594567.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            3581..4234
                     /gene="phoU"
                     /locus_tag="KRM55_002331"
     CDS             3581..4234
                     /gene="phoU"
                     /locus_tag="KRM55_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBH1594568.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            4392..5261
                     /locus_tag="KRM55_002332"
     CDS             4392..5261
                     /locus_tag="KRM55_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH1594569.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            5348..6784
                     /locus_tag="KRM55_002333"
     CDS             5348..6784
                     /locus_tag="KRM55_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBH1594570.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            6832..7659
                     /locus_tag="KRM55_002334"
     CDS             6832..7659
                     /locus_tag="KRM55_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1594571.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    7950..8212
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8288..10954
                     /locus_tag="KRM55_002335"
     CDS             8288..10954
                     /locus_tag="KRM55_002335"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBH1594572.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            11379..12089
                     /gene="rgaR"
                     /locus_tag="KRM55_002336"
     CDS             11379..12089
                     /gene="rgaR"
                     /locus_tag="KRM55_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBH1594573.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNTITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            13135..14166
                     /locus_tag="KRM55_002337"
     CDS             13135..14166
                     /locus_tag="KRM55_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH1594574.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKCSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            14299..15597
                     /locus_tag="KRM55_002338"
     CDS             14299..15597
                     /locus_tag="KRM55_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBH1594575.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(15711..15956)
                     /locus_tag="KRM55_002339"
     CDS             complement(15711..15956)
                     /locus_tag="KRM55_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH1594576.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            16104..16970
                     /locus_tag="KRM55_002340"
     CDS             16104..16970
                     /locus_tag="KRM55_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBH1594577.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(16974..17510)
                     /locus_tag="KRM55_002341"
     CDS             complement(16974..17510)
                     /locus_tag="KRM55_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBH1594578.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(17701..17904)
                     /locus_tag="KRM55_002342"
     CDS             complement(17701..17904)
                     /locus_tag="KRM55_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH1594579.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            18195..18959
                     /locus_tag="KRM55_002343"
     CDS             18195..18959
                     /locus_tag="KRM55_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1594580.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            19347..20660
                     /gene="prdC"
                     /locus_tag="KRM55_002344"
     CDS             19347..20660
                     /gene="prdC"
                     /locus_tag="KRM55_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBH1594581.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      21064..21149
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            21731..23878
                     /locus_tag="KRM55_002345"
     CDS             21731..23878
                     /locus_tag="KRM55_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBH1594582.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKPSDSQTPDVEKPSDGQMPDGEKPLDEQ
                     TPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEEDVKADEQSEINQ
                     VFTSKDSFISLWYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTLTFDYVIKGLVG
                     ASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQENQNEEAVKSIL
                     YAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWIILGQMDEQERLKQYQGSINLCD
                     KLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAGREELKPNDTGKPSLSNGLTKIN
                     FEKNEDGTYETEAVALVGYSGVVKLRLPDGVTAYDGDGNIIGTDEVEISTQQKFKLKS
                     VGKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQNLLSYTIEKKNG
                     QEVNFNIGLPTDDDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPP
                     VPPTEDAVLNPPVPPMEDAVLNPPVPPTDDTVLNPPVPPVSDTVEKTPELSRDDTIVK
                     SPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
BASE COUNT         9633 a         2578 c         4279 g         7649 t
ORIGIN      
        1 ttatataata ttttatattt ttatattatt aattatatgt gttgcaattg ctgcacctac
       61 tttttctggt gagtatcaga cacaatcaga tagcatcctt cgttgtacga aacatggaca
      121 tattcgtcta gcgtttacta aaatattagc tctattttct atatttataa taatgtttgt
      181 tatatgtatt tctatccatt tggcaatttc tgatttagct tttggtactg aatgtttgaa
      241 aacctcattt caaatgttgt tttctgtcat tagtctagta aatataaatt tactacaagc
      301 acagattctt atagctattg gtggtctaat ttcaatactt gcaatggtta gtttaacatt
      361 atttttatct gcaaaatgta aggattctct tacttctatg ctgattgctt tttctatttg
      421 cttaattcct atgggaatag gtgttagttg gattggatac ctattaccac cagggggaat
      481 tggttttaag attagtttat tatatcaaat gacatcattt aatttcttac acttaggagg
      541 tatgagtttt tggacaccac acattatact gtttttctcg gtgatagaaa tacctatttt
      601 tatatttttg gctattcgta cctattgcaa acatcaagta tcgtaacaat ttgatggaaa
      661 taatagtgat ataaactaga ggatacaata attatatatg tagtataaaa gttaaattta
      721 gttaacaaat cttaatagca gatataggta ataaattata cataaactgt attattatct
      781 atatctgcta ttttaatata gagaaacaac agtatattgt aaagtaaatg tcaaatatag
      841 ttttaaaagt aaaattaatg ttaaaaagta aatataattt tacacttgct taacttaatc
      901 ctaatataga tttaacttaa aaaaagtaga ataaaagtat aggaaatttg atgaagacga
      961 attataaaaa attaaatttt gaatacagaa cgaaaatcga taagtatatt ttaatgggag
     1021 ggtattatga tagtaaaatc tagattagta ggtttagaaa aaaatgacaa taatggcaat
     1081 aagacaaaat acgtaattga aaaagtagca aaaaatattt ttctacttag tgctttagta
     1141 gcagttgcaa gtttactttt gataatagga ttcgtatttt ataaaggatt aagaccattt
     1201 atatttgaag gatattcatt tatagacttt ttaactggtg cagattgggt tccttctgcc
     1261 aataaatttg gaatatcatc tatgatagta gcatcaatat ttgcaacact tggagcactt
     1321 gttataggag tacctgttgg tatattaacc tctgtattta tagcagaagt agcacctaaa
     1381 agattagcaa aaataatgtc accagcagtt gaacttttag caggtatacc ttcagtatta
     1441 tatggtgtat ttggtcttgc agtgatagtt ccaactatac aaagtatatt taatcttcca
     1501 aaaggtcaaa gtttgttagc aatagtaata gtattagcag taatgatgtt accaacaata
     1561 atatctgtat cagaaacagc aataagagca gtaccaaaag catacaaaga aggttcatta
     1621 gcacttggtg catcaaaaat agaaacaata ttcaaagttg tattacctgc tgcaaaatct
     1681 ggagtattag ccgcagtagt gttaggagta ggaagagctt taggtgaaac aatggcagta
     1741 atacttgttg caggcaactc accagttatg ccaactgcaa taacagatag tgtaagacca
     1801 cttacaacta atatagcact tgaaatggga tacgcatttg gtacacatca agaaatgcta
     1861 tttgcaactg gagtagtatt gtttacattt atattaattt taaacttagt tttaaataaa
     1921 ctttcaaata aggcggtaaa ttaagatgag aaagttcaaa gagaatctat tgaagtcatt
     1981 agtatatcta tcagcactat ttacaatagt atcattagta gttatagtgg gatttatatt
     2041 tataaaggga attggcaaca tgaattttaa tttcttattt agcaattatt cagcatcagg
     2101 tgatggtggt atacttccaa tgataattac aacattatat acagtagtag tttctatagt
     2161 tgtagcaact cctataggaa tattggctgc tatatattta caagaatatg ctaaaaaagg
     2221 aaaagcagtt acagctataa gatttgcaac tgaaagttta tcagggatac catctatagt
     2281 atatggatta tttggaggaa ttttctttgt agttacatta aaaatgggat attccatagt
     2341 tgcaggttca cttacagttg caataataat attaccagta ataattcgta caacagaaga
     2401 agctttaaaa acagttcctc aagcttatag agaatcatca ttggcattag gagctacaaa
     2461 atttcaaact ttatataagg tagtacttcc aagtgcaata ccaggaattt tatctggagt
     2521 aatcttatca gttggtcgta taattggaga atcagctgca atattactta cagcaggtac
     2581 tgtagccaag atgccaggtg gaatatttga tagtgcaaga acattaactg tacactcata
     2641 cttactgact aaagagagtg gagatatagc aacagcagcc agtataggaa ttgttttaat
     2701 agtaattgtg ttagcactaa acatgctagc aagatttgtt gctaagaaat taaataaagc
     2761 taattattaa atttaagagg tgtgaataat ggaattaatc gataagataa aaatgagtgt
     2821 aaaagatttg gatttatttt atggtgataa gcaagcatta aagaaaataa atatggatat
     2881 aaaagagaat aaggttactg ctttaatagg tccatctgga tgcggaaaat caacttttat
     2941 aagaacgtta aatagaatga atgacttaat cgaagatgta acaattaaag gaaacatttc
     3001 tgttgatgga gaggacatat atacctcaga tgatgttata aatcttcgta ctaaagtagg
     3061 aatggtattt caaaagccaa atccatttcc tatgagtata tatgataatg tggcatatgg
     3121 tcctcgtaca catggactaa gagataagaa gcaattagat aaaattgtag aagaaagctt
     3181 aaaaggtgca gctatttggg atgaggttaa agacaggctt aaatcatctg cactaggact
     3241 ttctggtggt caacaacagc gtatatgtat agcaagagca attgctatga gaccagaagt
     3301 tattcttatg gatgaaccta catctgcttt agacccaatt tcaacattaa aagtagagga
     3361 acttatagag gatttaaaaa aagactacac aatagtcata gttacacata atatgcaaca
     3421 agctgctcgt atatcagatg aaacagcttt tttcttaaat ggagaggtta tagaatttag
     3481 cgatacaaaa actatgttta ccactcctgt agataaaaga acagaagact atataacagg
     3541 tagatttggt taaaatatat aactataaag gagttagaca atggtcaata atagtttaga
     3601 tataagtatt gatactttaa aagaacaaac agtgcttatg atggaaaaat gtgaagaagc
     3661 aatagaaaag tctgtgactt gtatgataga gaaggattta gagggtgcaa gaaaagtagt
     3721 agaagatgat gaagaaataa ataaattaag agaagaaata agagataaga gtatagagct
     3781 aatagtatta aagcaaccaa tggcaaggga cttaagattt atttattcat taggtaatat
     3841 atctatagag cttgaaagaa taggagatta tgcagcaaat atagctagag aaatgttgaa
     3901 gataggtgga gaggcttata taaaagagct aatagatatt cctaagatgg caaaagaatg
     3961 taagtctatg atgtctcaga ctagagaagc tttaatctta tttgatgcaa gtatagctta
     4021 tgatgttgga actaaagatg atattgtaga tggattgtat gaacaagtac aaattgattg
     4081 tttaaaaata atgcatgaaa actcaaatac catagaccaa ggggtaaaac ttctacttat
     4141 aggaagatac cttgaaagaa ttggagacca tataacaaat gtatgtgaga agataatttt
     4201 tgcaattgag ggtaaaatgg ttgagatagg ataaaaaact gctttaaagc agttttttta
     4261 ttgtctaaat taagaaagaa ttgataaaaa aatatgatta atgggtaaat ttaaaaaatt
     4321 gtgatatact aggaacatat taaatatgag gatgcgtatt ttatataagg tgctttttag
     4381 gaggtggaac tttgaaactt caaaagatgg gtatgaggac tataaaaaca ggaattagtg
     4441 tcactttatg tatgattctt ggtgactatt tagtagagaa tatgttttat tctctggtag
     4501 catgtataat ttctgttcaa gatacagtaa aaggttcttt aaagacggga atcaatagag
     4561 tggaaggtac tattttaggt ggtataatag gattcatatt tgccatcatt aaagctggag
     4621 acccattttt atgtggtcta ggagtaatgt gctcaatata tttatgcaat ctgtttaaaa
     4681 taaagtcagt agtagttgcc tgtgtaacct ttctggctat acatctaggt gtaggaaata
     4741 gtgaccctgt atattattct ttacataggg tgttagatac atctgtgggt gttttgtttg
     4801 gagtacttgt taattattat gttgctagac caaattatct aaatagtgtt atagatgagt
     4861 ttaaaaagat agaagaactt tcaatgttgc ttattgaaga taaaattctt agaaaagaaa
     4921 atttaaatgt agagaaattt gaagaagaag tagaaaaatt agaagaaata tattcaaagc
     4981 ttattgatga gttggattat agtttgagtg aaactaatat agaaaaaatt gagaatgcct
     5041 taaggatatg tagagaaata cattttcata tgcagtctat agagttactt gaaaataaac
     5101 tttatttgaa agagcataca tataaatacc ttaagaaaac atataatgtg gataagctag
     5161 actggaatat agatgaagaa aaaagccctg tattcaacta tcatctaatg aaaataatga
     5221 ttgaaataga gttgttgaga aagctaaata aatcatatta ataatagtag ttaaataata
     5281 aataaaaaat agtatctttg taaatattaa acatatataa gtttaattta tggaggtact
     5341 attttttatg aatactagaa atgacaattc taaaatacta gaaatatata aaatgaagct
     5401 ttttggcgaa cttgtaaaag cagtgtggaa tgatgatata gaggatattg aaaacttacc
     5461 taataaaatt ttaaatgaag atttaaagga taatttaaat aattatttta gtggaaaatt
     5521 tgataaagat actatggtaa atttaattag ggtaactatg ggattggatg tgacagaaga
     5581 tacagataaa aatttaaaag agtcactaca tgaagctgta aatttagatg aagtcaaaag
     5641 accaataata tctgtaatat cagatgcttg caaatattgt gatgaaaata ataaggaaga
     5701 tgagtcatgt aagataagaa gtaagcatat taattgtaat gaggaagatg tatgtagtgc
     5761 ttgtggtgat tgtgtatcaa gatgtaagtt gggtgcaatt tcagataaaa tagaatttat
     5821 accaatgata aaattgttaa aagatataaa gagccctgta tatgcaatag ttgcaccagc
     5881 ttttgtagga cagtttggga aagatgtaag ccctggtaaa ttaagaactg cattaaaaaa
     5941 gataggattt gaagatatga tagaagttgc tttggcagca gatatgctta ctgcaaaaga
     6001 agcatatgat tattatgagc atatgaaaaa ggacgaagaa ggatgcttta taactagttg
     6061 ttgctgtcct atttgggtta gtttgataca aaatagtttt cctcagatat tggaaaatgt
     6121 atcaccatcc gtttctccta tgattgcttg tgggagagct gtaaaaattt taaatccaga
     6181 tgctaaagtt gtattcatag gtccttgtat ggcaaaaaag aaagaggcaa tgttagaaga
     6241 tataaaagat gcagttgatt ttgtgcttac atttaaagag ttgcaagaaa tatttgatgc
     6301 attagagtta aatccagcaa taatggatga gagtaataga gtagaggcgt ccctttcagg
     6361 tagagtttat gctagaacag gaggtgtaag taaagcagtt aagttatcag ttagaagaat
     6421 tgacaaaaat ataaaatttg aagaaaaggc atttgaagga acaaaagagt gcatggacgg
     6481 tctaaagaaa gttctaaata aagaaataga agctacattt atagaaggaa tggggtgtgt
     6541 aggaggctgt gtaggaggtc cgaagcgtat tttaagtgtg gaagaaggta ctaagaatgt
     6601 tgatgaatat agtgaaagta cgaatatgga aactccattt gataatttaa atgtattaca
     6661 atttttaact tctttgggaa tcaaaagagt agaatcttta ggagaaaaag aagaagaaaa
     6721 ggttaaaaaa atatttagta gagatataaa aagtaataag aaagagaata aatataaaaa
     6781 ataacttttt aagtcttaaa cttatgcttt tataaaaggg agatatgggg gatgaaaatt
     6841 aaagataata aggctgtttt tcatgtattt ataaggatat ttcttatagc tgttttaatt
     6901 ttaactggaa cattattgga ggaaaaaatt aataatgttc cagttgaaaa tataagttca
     6961 aaaggtgaaa atacactgga actgctttct caaagtaata ctttaggaga aatcatatac
     7021 aaagcatctc aagaagaaac aaaaggtcca ggggctactt ctgaaaaagt agcatacata
     7081 acaatagatg atggtccatc aaaatataca aatgcactac ttgatatttt aaaagaaaat
     7141 gatgtcaaag cgacattttt catgcttaat cagaatatga aaaaccacaa ggaagaagta
     7201 aggagagtct tggaagaaga aaactcaata ggttttcata gtgtaagtca tgatatacat
     7261 aagttatata aaagcccaga agtaacagtt ggggaattta atacatgcaa taatactcta
     7321 caagaaataa ctggtcagag ttcaaaatta ataagattac catacggaag taaaccatat
     7381 atgccagaag gttcatataa taaacttatg gcaaatgatt atttaatttg ggactggaat
     7441 ttggatacac aggattggaa gtcttctaca agtcagatag taagtaatat attatattat
     7501 ggaagaaaaa gagatgaatt agtagtatta attcatgaga aagagcaaag tctaaatgct
     7561 ttaaataata ttataagaat cttaaaagag agaggatata caatattgcc aattacagaa
     7621 aatataacac ctaaaaattt ctggcaagaa aacttataat aaatttaaat atagtaaaag
     7681 ataaagtaaa ttatttataa aataaaacat ataatataaa aaatacgaat aagaggtata
     7741 ctgtaaggat aatataaaat taatgagaaa gcattaaaat taaaataatc ttgcaattat
     7801 tgacattata agacagaata actgtaaaaa catattttaa aatataacaa ctatataaaa
     7861 gagaatagac ataattaaga aaattcagaa aaaataaaat aaaaataatt gacaaagaga
     7921 ataatatttg tatataataa tatgtaatat taaagactga gaagaagagg agtaagtaaa
     7981 tactactaaa agagaggaaa attcactggc tgtaagattt tctaagtata agatttactg
     8041 aatgtagctt tggagtttct aaactgaact ataagtaagt ttagacggtt agaaccgtta
     8101 aattctttga gagtcaaagt tgataaaata acattaacca ataatttaat tatatgttaa
     8161 tgtattttaa gctttggaat taaggtggta acgcgagctt ttcgtccttt ttaaagagga
     8221 tgaagagctc ttttttattt ctaaagatat ttaaaaaatt tatttataaa atacaggagg
     8281 caggacaatg gaaaatacga atttatcaaa aacttataac ccaaaagatt ttgaggctag
     8341 gctatataaa aaatggatgg atgaagggta ttttaaatct aaaccaaatc cagataaaaa
     8401 accatttaca ataatgatgc caccaccaaa tataacaggg caattgcata tgggacacgc
     8461 tcttgaccat acacttcaag atatattaat cagatggaaa cgtatggatg gatatgaagc
     8521 tttttggctt ccaggaactg accatgcttc tatagcaaca gaagttaaag ttgttgaaag
     8581 aataaaaaaa caagaaggca agacaaagta tgaaataggt agagaagaat ttttaaagag
     8641 agcctgggaa tggaaagatg aatttggagg aaaaatatct aatcagctta aacaactagg
     8701 tgattcttgt gattgggata aagaaagatt tactatggat gaagggtgta atgaagcagt
     8761 tatagaattt tttgtaagcc tatatgaaaa aggtcacata tacagaggaa atagaataat
     8821 aaactggtgc ccagattgca aaactacttt atcagatgca gaagttgaac atgaagaaca
     8881 cgacggaaac ttttatcata taaagtaccc actaaaagat agtgaagact ttttagaaat
     8941 agctacaact agacctgaga caatgatagg agatactggt atagcagtaa atccagaaga
     9001 tgatagatat aaacatttaa taggaaaaac agcaatactt ccattagtag gaagagaact
     9061 tccaatagtt gcagatagtt atgttgattt agagtttgga actggtgcag ttaagatgac
     9121 tccagcacat gaccctaatg attttgaagt aggattaaga cataatcttg agcagttaaa
     9181 tactatgaat gaagatggaa ctatgaatga agtttgtgga aaatatgaag gtatggatag
     9241 atttgagtgt agaaaagcta tcgtagcaga cttaaaagaa caaggttacc taattaagat
     9301 aaaagagcat aatcataatg taggaacttg ttatagatgc catacagtag ttgagcctag
     9361 attatcagag caatggtttg ttaagatgga agaacttgca aaaccagcta tagatattct
     9421 taaaaaagga gaattagaat ttgttccaga taaatttgat aaaacttatt tacaatggct
     9481 agaaaatata agagattggt gtatatcaag acaattatgg tggggtcatc aaataccagc
     9541 ttattattgt caagagtgtg gagaaatagt agttgctaga aaaatgccag ataagtgtcc
     9601 taaatgtgga agcactcatt ttaaacaaga tgaagatgcc ttagatactt ggttcagttc
     9661 tgcattatgg cctttctcta ctctaggatg gccaaataag actgaagctt tagattatta
     9721 ttatccaaca agtgtacttg ttacaggata cgatataata ttcttctggg tagttagaat
     9781 ggcatttgca ggtatgttct gtatgaatga aaagccattt gaccatgttt tggttcatgg
     9841 attagtaaga gattctcaag gtagaaaaat gagtaaatct ttaggaaatg gtatcgaccc
     9901 attggagata atcgagcaat atggagctga tgccctaaga tttacattaa caactggaaa
     9961 ttccccagga aatgatatga gattctatat ggaaagagta gaatttgcta gaaactttgc
    10021 aaataagttg tggaatgcat caagatttgt atttatgaat attgatgaag atataattaa
    10081 aaacatgact agagaaagtg ttaaagagga cttaactcta gctgataaat ggataatatc
    10141 aagagcaaat aatattgtaa aagaagcaac taataacatg gataagtttg atttaggaat
    10201 agcacttcaa aagatatacg attttacttg gtcagaatac tgtgactggt atattgaaat
    10261 ggttaaacct agattatatg gagaagatgc aaatgctaaa tctgcagcat tatatacatt
    10321 aacttatgtt cttgaaaaaa tattaaaatt attacatcca tacatgccat ttataacaga
    10381 ggaaatatat actcatcttc ctactgttga aggatgtata atagtatctg aatggccaaa
    10441 atataatgaa gaagataaca tggctgaaga agaagatatg atgaacttat tgatggaagg
    10501 tataagaagt ataagaaatg tgagagcaga aatgaatgta ccaccttcta agaaagctaa
    10561 attgataata atcccaagtg aagaaaaaat agaagctatt gagcttggta aagactattt
    10621 tataacttta gcatctgctt caaatgtaga gatagcaaaa gataaatcta atgttccaga
    10681 agatgcagtt ggagtagtta ttgatggtgt tgaaatattt atacctctta atgaattagt
    10741 tgattttgaa aaagaaattg agagattatc taaagaaaag aaaaagttag aaggcgaaat
    10801 aaagagagtt aatggaaagc ttgcaaatca aggtttctta gcaaaagctc ctgaaagttt
    10861 aattgaagaa gaaaaagcaa aaaaagaaaa atttgaagag atgattaaat ctgttgagga
    10921 aagattaaca aatttagaat ctaaaataaa ataaatataa gaattagtaa aaacatacaa
    10981 aaagtatata ttctatactt tttgtatgtt tttctttata tatatacaaa tatgatgtta
    11041 taattcttta cagatgtgtt atatttttat tttatgttgt gaatatatga attttatgtc
    11101 ttaaaattta taagcaataa aaatttgata tattatgatg tttaatatag ggtaataaat
    11161 acatattata tttattttac tatatttttt tacataatat atctagaaaa gtataggaat
    11221 ttatcgtaat ttaagtttaa atattaaaga gaatttctat aagtagttta atcgacaatt
    11281 taaatttata aagaaattta aatttgaaag ctagtgagta cagtttggaa attgaaataa
    11341 agtaaactaa atgatatttt agatttggag gtgatattat gttcagggta gttatatgtg
    11401 atgacgaaaa aatacaaaga agcatactaa aagagtttac agaaaaactt ttgtctgaaa
    11461 gatgtctaaa ttatcaaata ctggaatttt cctgtggaga agatttaata tccaaatacc
    11521 cagaaaaaat tgatattata tttttagata tccaaatgaa agatatcaat ggaattgagg
    11581 tggctaaaaa aataagaaag tttgatgaaa aagtagaaat tatatttaca acggcttttt
    11641 cagagtatgc cccccaaggt tatgaagttc gtgcttatag atatttagta aagcctatag
    11701 agtatagtaa ctttgcaatg ggtgtaaatc tttgtattga taaccttcaa agaaagaagg
    11761 agcgttatat agttttaaat agtaaaaaag gatttaatag aatactgata gattctattt
    11821 tatatgttga aactgtaaag agagatttag ttgtacatac aataggtaga gattataaag
    11881 ctaatatgag catgaaacaa gcagaaaaat tactgtgtga aaatggcttt tttagatgtc
    11941 atacaagttt tattgttaat ttaagaagaa tagaagatct tagggataat acgattacta
    12001 ttaatgaaca atttatacct ataagtaagt atagacttaa agatttaaaa gtagcattaa
    12061 caagcttgtt atgtgatata atgtattaat tttaaaaagg taattgaaaa tatcgtaaaa
    12121 aagatttaat gtcatcacag ggctattgat tgaaactgtc ttaatatata aaatgttatt
    12181 tatattaaga cagttttatt atgcaaaata gcagtttata gatttttaat atggtttaat
    12241 atgtatatgt agagtttcca ttataatagc atgattatta attagtagct tgattatcaa
    12301 tatactatta ttgattttta tatgcattat atgtattttt agaatatgat taccttttta
    12361 aaataatgac tatttataaa actctataga tatttgtttc atttagctac gcatacttta
    12421 attaattata ttaatattta atggagtaca atataaatat taaagcgaca tcttatagtt
    12481 tattgaacct atagtaatga attaataaat agtttaattc tatgaaaaga tttcctttta
    12541 tgcaatttat ttattgaaat atgatataat atataaaggt gtaagtatta gttgttaaaa
    12601 taatatttat attagttttt atgcatactt ggtataagtt tttcatatat tgattaaaat
    12661 tgatgttgat ttattatttt tagtattttt tcaccttttg attcatactt tgtagaatgg
    12721 tgtattttct aaaactgatt ataagacaag ttcattcaaa ttagcatttt tatatcatat
    12781 aaataattgt tccccctaaa taagatttag atgtatagta ttaaaatcaa aaagtataaa
    12841 ataaaattga tgcttaatca tagataaata ttaataaaat atacaagggg attgtctaat
    12901 aaaaagataa tctccttttt tacaaataat tctaaattgt gatataaatc taaaaatttt
    12961 atcttaacat ttaaccattt aatgataata attgatataa taaatataaa ttaaatatat
    13021 ggtgtactta ttttatgttt ttagcaagaa atatagcatt taaaagataa attgtgcaac
    13081 ttaaatcaaa gtttaagatg aactattaac atagatatat taaaaacttt tgtaatggag
    13141 aatatatgtg atatgaataa taaagttaag gttgcagtat tagatacagg aatagacaaa
    13201 gaacatgatt acttaaaaga taatttagtt ggaggaattg cttttgaatg tatgcatgat
    13261 tatatcttta tatcagataa atttgatgat gaagatggtc atggaactgc ttgtgcatca
    13321 ataataaaga aagagtatga agatgtagag ttatttgtaa taaaaatttt gagaaaagat
    13381 ggtattacaa atataaaagt tcttgaagaa gcattaagat accttttaga cactaacata
    13441 agattaatta atttaagttt atcagtcata ggagtagaaa gtgttaaggg cttatttgaa
    13501 gtttgttatg aattgtttag aaaaggaaaa ataatagtat gttcactcgc taatgatttt
    13561 gacttaagtt atccagctat gtttaacaat gttataggtg taagaggatt tactttagat
    13621 ggagatgatt cattttggta caacaaaaaa tatgatgttc aatgtgttat ggatagcaat
    13681 tcatatataa gttgtgatat aaataattcc tatagattac caccaaaatg taatagttat
    13741 ttatcagcaa agcttactgg taaaatagct aagatattat cagaaaaacc aggcataaca
    13801 atatctgatt taaatgataa gcttgaatca ttagcaacta gaaatcattg ggatagttgt
    13861 gattttgatg agtgtagtag aattgtaaac tttaaattgg atttgtatga caaagaaaat
    13921 gctcttttta tgaaagttgc tgacgttgtt agggattgct tagatattga agagaataat
    13981 gaaaaactct ttaagtgtag cctttttaat aaggagatag gcttggttta tgataattgt
    14041 tttaatctgt tgaaaaagct agagcataga tttgacataa agtttaatta tatggacatc
    14101 tcaaaatatg acttagtttc aatatataca ctgactgaat tagtggaaag atataaaaac
    14161 ttataaataa agatttgtag ctaaatttaa tgtagaaggt attaaattat atgtattctt
    14221 tgtcagtaga ttaaaagtaa aaaatatact ataattagat agcataagag aaaatgccaa
    14281 tacaggggga gttagataat gaaatatgaa gaagcattag agtacatatc acaaactaat
    14341 aaattcggta taagattagg attagaaaat atcggaaagt tattagaatt attaggaaat
    14401 ccacaagaaa ctttgaatat aatacatgta gctggaacta atggaaaagg ttctgtgtgt
    14461 tcttttgttt ctaatatact aagagagtgt ggatataaag ttggtttata tacatctcca
    14521 tatttagaaa cttttactga gcgtataaga gtaaatggac aaaatatacc acaggatgat
    14581 gttgctagaa taattgagtt aataaaagaa aaaatagaga ttatggtaaa agaaggctat
    14641 gcatatccaa cagaatttga agtggttact gcaatggcat tttattacta ttcagaacaa
    14701 aaggtagact ttgtggcatt agaagttggt ttaggtggca gatatgatgc tacaaatata
    14761 ataacaaaat cacttgtaag tgtgatagta tctataagtt tggaccatac aggtatactt
    14821 ggagatacaa tagaaaaaat agcgtacgaa aaggctggaa taataaagga aaatggagta
    14881 gtactagtat atgaccagac tgatgaagca aaggatgtta taaagtcagt ttgtaaagag
    14941 aaaaaagcta aatatataga agttgatttt gatgatataa acataaaaaa atcagatata
    15001 aattctcaaa tatacgattg tactgtaatg aaagaaactt atagagacct tgaaataaaa
    15061 ttgataggcg aacatcaaat aaacaattct atcttggcaa ttagtgtaat aaaatatcta
    15121 aaagacataa ataaattagc aaatataaat gaagaatcta taagaaaagg acttataaat
    15181 actaaatggc caggaagaat agaaaagata aaggaaaatc caatttttat aatagatggt
    15241 gcacataatg aagatggagc aaaatctttg gcaaaagcac ttgataagaa ttttaaaggt
    15301 agaaaattaa ccttattaat aggtatgtta gaagataaag atattgatag tgttttagag
    15361 atattgttgc cacattttaa taaggtaata acaacaacac caaataaccc aagggccata
    15421 aattcagata tattaagaga aaaagtatta aaatatgtag atgatgtaac atcaaagcat
    15481 gagatagagg atgcagtaaa ttatacatta gaaacatcaa gtgaggatga tattataata
    15541 agtgcaggtt cattatatat gattggtaca gtgagaactt tagtaaagaa attataattt
    15601 tataaaataa atatacaaat aaaaatataa aaaagagttg tctaaaaaat ggacaactct
    15661 ttttatataa aataagtttt taataatttt actgatgttt atataagtaa ttatatagat
    15721 tgacgtatag ctttagataa ttggtctggg caagaagtac cttttccacc acagtcaata
    15781 ccatttaatt tatcagcaac ttcaagagca ttttggccaa ttattaagct tctaagtcct
    15841 gataaattac cattacatcc tcctataaac tcagcatcaa caatcacatt attttcatca
    15901 acttcaaaaa tcatttctct acaacataca ccacttggat taaatgttac tttcattaaa
    15961 aagacctcca ttaaatatta tttctttttt taacattaat aataatacca aatatatgcg
    16021 taataatgca actataaagc ataatacaag ctaatgaaat aatatattat tgtagtatat
    16081 gtattgtaga gaggaggggt tatatgaaaa tctatatttc taactactta tcaaagagta
    16141 ttagcatagt tgattattct acacttgaac tagaaaaaga aatagtatta gaagataata
    16201 tatatccaca ccatttttgc atagaaaaag aaaaaaattt aatatacata cctagttcaa
    16261 gtaatgggat actctatgtc ttagatttaa gtaatgataa aataattgat actgtctcta
    16321 taggaggaag tcttagtcaa gttgtactta gcgataatga attgtttgtg gcaaatgaag
    16381 attctaatag tatatatgta ctagataaaa acacattaaa tccaatagga attattggag
    16441 ttgataatat gccacatgga tttgactttg atagagaaag caaaaagtta tatgtaccgt
    16501 gtataaactc gatagtatgt atagatacaa ttaataaaaa tatacaaaag aaaataaata
    16561 tggactttag agcttggcat atagaacttg ataaacaaaa gaaagaaatg tatatatcaa
    16621 cacttgatgg aaagcttata ataatagatg aagtaagcat ggatataaaa aaggtattat
    16681 atgaattttt attaccagta gaaataagat ttaattatag tggcaaaaaa gtttatgttg
    16741 ctgatttggg ttataataat gtaagaattt tagattatac aacgagtaga tacattggaa
    16801 atattgaaat aaatgggatt ccccaaggat tagaaatatc taaagatgaa aagttactat
    16861 ttgtatcaga tacacaagaa aattcagtaa aagtttatga aactgcaaat aacaaattaa
    16921 taaaagaaat caaggtagga aaagagccta caactataat ttgtttgtag gctttaatgt
    16981 atgtctctta taagtaaatc gataacttcg gcatacatat aagatgcatt atttttccag
    17041 ttattgcaaa taagttttgc ttgtttctct gatgaaacat ttagatttaa atctattaag
    17101 ttagactgat tttctatgac tctaaggttg acaataaatt cattatcact ttgttttaca
    17161 aaactagact ttacttgagt atctgctagt agattttctt tgttagaatc tatatacttg
    17221 tctatttttt cagtaacact agtaggtatt cgattaaaga agtattctag actttctacg
    17281 cctctttgag taagagcata atattctctg tcagagtctt tatatgtagt caaaaactta
    17341 gattccataa gctgagataa aagctgttgt aatgaaaaat aattcatcat ctcagtctct
    17401 aatactactt gagttatttg agaattagtt aaatccattt taattttttc taatatatat
    17461 aaaattaaaa gtttgtgata ggctaattct tcagacgagt tttcaaacat aaatatcatc
    17521 ctccgtcaaa ctatttctat atataatata ttaaactaat ttgtacaaaa ttaaaagaac
    17581 aatttgtatt gtattattaa tctttaataa ttcatataaa aacaatttta taaataaata
    17641 tagaaaaaca gggctgctaa ttagcagccc tgttgatacc caggtgtcaa aatttactat
    17701 ttattttcca gccatttgtc tttcagccat ttcaactaat ttcttagtca tatatccacc
    17761 aacatatcca ttttctctag ctgttaagtt acctttgtct atgttttcat agttagataa
    17821 acctatttcg ttagctattt ctaatttcat ttggtttaaa gcagcttttg cttctggaac
    17881 tactgttctg tttgaatttg acatagtaaa tttcctcctc aaataattag tttatgatgt
    17941 ctaacaacac ttttatttat gtgatgttaa tactaatttc tccaaaataa aaataatata
    18001 tacagaaaaa taaaggtaaa aatgtaaaaa atataaaaaa attaaataaa tgagtatttt
    18061 agagagttta attaggtcaa tataggtttt atttttttag ttattgtctt ataaattaaa
    18121 tattacagta cttttttgag ctgaaaaaaa ataaatttta aatatagaag aaattatttc
    18181 aaagggggaa tagtatgaaa agagaagtta aaaggactaa agctttgata tatagtgttt
    18241 tatttttttc attattatta gtgttaatat ttgtttttgt ttatggaata aaatacatat
    18301 gttctaaatc tgacaattca aaaatgccta tatataaagt tgatacaaat gagaaaaaaa
    18361 tagctttgag ttttgatgta gcatggggaa ctgataatat ggatgatatt ttaaaaattt
    18421 tagataaaca taatgtaaaa gctaccttct ttttagttgg tagttgggtg gatgataatg
    18481 aagaaattgt aaaagctata gatgaaaaag gacatgaaat tggaaatcat tcaaatactc
    18541 atgccaattt gaaggaaata tcaaaagaag acataacaaa agagatagaa actacatcag
    18601 aaaaaatata taatataaca ggaaaaagga ctaatttatt tagacctcct tttggggacg
    18661 taaacaataa agctatggac atttgtagtg atttaggtta taaagtaatt aagtgggatg
    18721 tagattctat agactggaag gagcttggac caaatcatgt aattgaaaaa gtaataaaag
    18781 aatctcaacc tggttcaata gttttattcc atgctaatat aaatgatgta gataactatt
    18841 tggatactat aataagtcga ctaaaaaaag atggatacag tctagtcaaa atatctgatt
    18901 tgttgtataa agataattat gtagttgatt ccaatggagt gcaaaaaact aagaattaat
    18961 aagtaataaa tgtatatttt aagtaaagtt gtgataaatt atatagtata tgttagaaaa
    19021 gtgtcgataa aaagacggtg tctatttttt gacacttttt atacatgtat gcaatatcaa
    19081 taattataga ttaaattgat taaaaaagtg tctaataatt gacttttttt gatgggttta
    19141 aaaatttaga agaattaatg aatgctgtaa gacagtattt ccaaagggta taagtttgtt
    19201 taaaagttgg catagaaatt gctttgttaa taagcgatat gttctataga aataaacaat
    19261 atgttaagac cttataatag aaaaatagca ttaacattat ttgaacagct tataaaaaaa
    19321 ttaatatact taagggggcg tactagttga acaaactata ttctatttta ttaaaacaac
    19381 acgttggtgg tccagataag ccagtagtaa gtgttggaga tgtagtaaaa aaaggaactc
    19441 taatcgcaga accaactgga ttaggggcaa atatttatgc cagtgttagt ggaaaaataa
    19501 gtgaaataaa tgaccaagcg atagtaattg aagctgatga agtacaagaa gatacttttg
    19561 aaccattaaa aggagaaggt atacttgact taattaaaga agctggagta gtaggaatgg
    19621 gtggagcagg attccctact catgtaaaat taaacataga tttaaatggt ggaacaatat
    19681 tagcaaatgc agctgaatgt gaacctttat tagctcataa tataaaagaa atagaagaaa
    19741 gaccagaaat agtttatcaa ggtataaaat atgctatgga agttactaat gctggaaaag
    19801 gtatgctagc aataaaaagt aagcatccaa aagcaataga agctttcaaa aaagtaataa
    19861 agccaggaga caacatagaa gttgcagaat tagttgatat gtacccaatg ggagaagaga
    19921 gagcaatagt aagagacgtt ctaggaaaat tacttgagcc aactcaatta ccttcagagg
    19981 ctaatgcagt agtaataaac gtagaaacac taactagaat agtagaggct gttgagcaaa
    20041 aaagaccagt tatatctaaa aatataactg tagttggtca attaaacagt ggaaaagaat
    20101 ctatagtgtt tgaagatgtg ccaattggaa caactgtcgg agaattaatt gaaagagctg
    20161 gtggaataaa aggtgaatat ggtgaaataa tcctaggagg acctttcact ggtaaagcta
    20221 ctactttaga tgctccaata actaaaacta gtggtggtat aatagttact atgccatttg
    20281 ttaatgaaaa gagaaaaatg ggtcttttag tttgtgcatg tggacctaat gaagaaagaa
    20341 tgagagatat agcaactaaa atgggagtta ctgatatagt atcagttcaa aaatgtaaac
    20401 aagctcaaga aattaaaggt gcattaaaat gtgaaaatcc aggacactgt ccaggacaag
    20461 ctcaaaaatg tattgaattt aagaaagctg gagcagaagt tatattaata ggaaactgta
    20521 ctgactgtag taacacagta atgggttctg caccaaaatt aaaattaggt gtatatcata
    20581 ttactgacca tgtaatgaga acagttaatc acccattaat aagaagaata aaaggtgatg
    20641 taagattaaa aataaaataa tagataaata gaagttagac atctttagaa gtaaaactta
    20701 aaagttactt ctaaggatgt tttttaatgt attttgaggg caatatatat attgtaaaat
    20761 aaatggaaaa aatagacaaa atatgctaga tattgtataa tgataacaat agctattaca
    20821 attaatattg gacaaaaata atgatactca agtatgtggt ttgtattaat atgcatatta
    20881 tattaagtca actatccgat agagtaaaag gtttttgtga tatttgaaga tactctatag
    20941 tatctttttt attataaaaa ctaatttttg tcttttatta gataagtatc taggatacta
    21001 atttatattt tattgagttg ttaaaaaagt gcacttaaaa agttaaaaaa gaaaaattaa
    21061 aaacctattt atagaaactg tgaagtatat cttaaacctg ggcacttaaa agatatatgg
    21121 agttagtagt gcaacctgct ataaatataa ataggagtaa cttttaattg tcaaaaatat
    21181 ataaaataaa tacataaata agtaattaat agaagataga tataaatata tttttgaaat
    21241 gctccctgca ttcataacga gtgtagagtg gcagatatct gcccaaaact cctttaattg
    21301 ctggaagttc ctaaagctaa ctaaaccaca acataatcat gaaataagga taagtgtgat
    21361 agagtgtgca tttaataagc acttgaggtt acgaaagtag aaaaaattag ttagatagca
    21421 taaggttaaa tcctaagtgc cttgaaaatg gataatcagc aggtaagctt cgaaaagaag
    21481 aaacttcaac gactagagag aaatctcgta cctacaagtg tggggaaatg gggagtacct
    21541 aatttatggt taggtaatga tatagtctgt gcttaataga aatattaaga agttcatagg
    21601 agaactggtt aggagtaacg accctaattg aacacactaa agatgtatta ttgaataaga
    21661 ttcatataat atttaataat tttaattata ttaagtgaat acaatatatg tttttagtat
    21721 caggagaatt ttgaaaacaa aaattaaaaa atcaagtata atcagtttag taattgcttt
    21781 tagtatggta tttactgcat ttacaccaat agtatcttat gctgacgaag tgactagcaa
    21841 tgatacaata cttaatggag aagaacaatc aaatggtcag acaccagatg tagagaaacc
    21901 atcagacggt caggtaccag atggggagaa accatcagac agtcaagtac cagatgggga
    21961 gaaaccatca gacggtcagg taccagatgg ggagaaacca tcagatggtc agataccaga
    22021 tggggagaaa ccatcagatg gtcagatacc agatggagag aaaccatcag atggtcagat
    22081 accagatggg gagaaaccat cagatggtca gatgccagat ggagagaagc catcagatag
    22141 tcagacgcca gatgtagaga aaccatcaga tggtcagatg ccagatgggg agaaaccatt
    22201 agatgagcaa actccagaag aagaaaaacc attggaagaa gaaatagtta tagaggaaat
    22261 gagtttaaaa caagatattg ataaaattct tgatatgact ttatctcaaa taaataaaat
    22321 agtatataac ttttgggaag atgaagaaga tgtaaaggca gatgaacaat cagaaattaa
    22381 ccaagttttt acttcaaaag actcatttat tagcttatgg tatgacaaaa aagcaaaagt
    22441 aaaaaattct tgtttactaa aagaaataga tggttcagat agaccttatc atgatttaag
    22501 atttgatgat attacaaaga ctttaacttt tgactatgta ataaagggtc ttgtaggagc
    22561 aagctcaaaa gacgacaaat atgtaataga aggtgaagat ggagagcaaa ctgcattttg
    22621 ttacaataat catttaagac caccaagtag taatggaaag agtccatatt taccagcaga
    22681 agattttaat ggtcaagaaa accaaaatga agaagcagtt aaatctatac tatatgcagg
    22741 ttctgaattt gatggatttg gatataagca acaatttaat ttaggtggag aagaaaatga
    22801 attgatgact tactcagcta ctcaaagtgc aatttggatt attcttggac aaatggatga
    22861 acaagaaaga cttaagcagt atcaaggttc tataaacctt tgtgataaac ttatagaaag
    22921 agcaaaaact gaagaggaaa gagcggagta tcagaagaag aaagaagtag ctataaatat
    22981 aaaagcttat ttagaagcat tgttaaaagc aggtcgtgaa gagttaaagc caaatgatac
    23041 aggaaaacct agtttgagta atggtttaac taagatcaac tttgaaaaaa atgaagatgg
    23101 tacttatgaa acagaagctg tagccttagt aggttatagt ggtgtagtaa agttaagact
    23161 accagatgga gtaactgctt atgatggaga tggtaatata ataggtacag atgaagtaga
    23221 aatttcaaca caacagaaat ttaaacttaa gagtgttgga aaaccagatg ccaaagctaa
    23281 tatttctgct gtatcttatg attatatttt tccaaaagct attcaatatt ataaggcagt
    23341 gcttgattta ggacaaaaag accattcatc ttcattacca tctagtaagc aaaatttatt
    23401 aagttataca atagagaaaa agaatggtca agaagttaac tttaatatag gtctaccaac
    23461 agatgatgat gatgttgtaa atccaccagt gccaccaaca gatgatacaa atggacataa
    23521 gccaaaacca tcaccaccaa tagatgatac agtaataaat ccaccagtac caccaatgga
    23581 tgatacaata ataaatccac cagtaccacc aacggaggat gcagtgttaa atccaccagt
    23641 gccaccaatg gaggatgcag tgctaaatcc accagtgcca ccaacagatg atacagtgtt
    23701 aaatccacca gtaccaccag taagtgatac agtggaaaaa actccagaac tatcaagaga
    23761 tgatacaata gtaaaatcac caaaaacagg tgatgaaact cagctaatgt catatgtatt
    23821 tattagtgtc attgcaattt gtggattagc gtatcaatgt aaaataaaaa gaaattaatc
    23881 tagattatta ttaagtttaa aataaaaagt ctcaaattga tttataagtc attttggggc
    23941 ttttttatgt aaatataata tgcaaatata gtttgtttaa aaatatctat tttaattata
    24001 ttcttaaatt tatgattgga tacaggcatt cattaattgt ttgatgaata gaaaaatgtt
    24061 ttgaaggtga aaatagtatt gaaaaaataa tatactaagg gtataattca tttgatttca
    24121 tttgtataaa tttaattat
//
LOCUS       DAEPXW010000059        23368 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.060, whole genome shotgun sequence.
ACCESSION   DAEPXW010000059 DAEPXW010000000
VERSION     DAEPXW010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23368
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.060"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(207..887)
                     /locus_tag="KRM55_002346"
     CDS             complement(207..887)
                     /locus_tag="KRM55_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594583.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(937..2952)
                     /locus_tag="KRM55_002347"
     CDS             complement(937..2952)
                     /locus_tag="KRM55_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1594584.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSMVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(3024..3701)
                     /locus_tag="KRM55_002348"
     CDS             complement(3024..3701)
                     /locus_tag="KRM55_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594585.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(4281..4364)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(4597..5439)
                     /locus_tag="KRM55_002349"
     CDS             complement(4597..5439)
                     /locus_tag="KRM55_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1594586.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(5691..7475)
                     /gene="pepF"
                     /locus_tag="KRM55_002350"
     CDS             complement(5691..7475)
                     /gene="pepF"
                     /locus_tag="KRM55_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH1594587.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(7541..8206)
                     /locus_tag="KRM55_002351"
     CDS             complement(7541..8206)
                     /locus_tag="KRM55_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH1594588.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(8357..8518)
                     /locus_tag="KRM55_002352"
     CDS             complement(8357..8518)
                     /locus_tag="KRM55_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBH1594589.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(8596..9105)
                     /locus_tag="KRM55_002353"
     CDS             complement(8596..9105)
                     /locus_tag="KRM55_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBH1594590.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            9311..9529
                     /locus_tag="KRM55_002354"
     CDS             9311..9529
                     /locus_tag="KRM55_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1594591.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            9547..11493
                     /gene="feoB"
                     /locus_tag="KRM55_002355"
     CDS             9547..11493
                     /gene="feoB"
                     /locus_tag="KRM55_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH1594592.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFANLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIIEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(11672..12727)
                     /locus_tag="KRM55_002356"
     CDS             complement(11672..12727)
                     /locus_tag="KRM55_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1594593.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(12775..13575)
                     /locus_tag="KRM55_002357"
     CDS             complement(12775..13575)
                     /locus_tag="KRM55_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1594594.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(13568..14359)
                     /locus_tag="KRM55_002358"
     CDS             complement(13568..14359)
                     /locus_tag="KRM55_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1594595.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(14399..14821)
                     /locus_tag="KRM55_002359"
     CDS             complement(14399..14821)
                     /locus_tag="KRM55_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBH1594596.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(14837..15316)
                     /locus_tag="KRM55_002360"
     CDS             complement(14837..15316)
                     /locus_tag="KRM55_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1594597.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            complement(15448..18204)
                     /locus_tag="KRM55_002361"
     CDS             complement(15448..18204)
                     /locus_tag="KRM55_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1594598.1"
                     /translation="MRDEILSFINECVLFNNFDELKKESGIVTEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            complement(18802..19605)
                     /gene="proC"
                     /locus_tag="KRM55_002362"
     CDS             complement(18802..19605)
                     /gene="proC"
                     /locus_tag="KRM55_002362"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH1594599.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            complement(19931..22300)
                     /locus_tag="KRM55_002363"
     CDS             complement(19931..22300)
                     /locus_tag="KRM55_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBH1594600.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKRDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKQDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDTRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            complement(22305..23213)
                     /locus_tag="KRM55_002364"
     CDS             complement(22305..23213)
                     /locus_tag="KRM55_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH1594601.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
BASE COUNT         7520 a         4083 c         2549 g         9216 t
ORIGIN      
        1 ttatctatct tttcaaatat aatctataaa ataatagttc cattacgcat ttttttatat
       61 aataaaactg actgtaattt aactggcaaa gtctagaaga ataggcttta tcaattaaat
      121 tacagtcagc tattttataa taatttagtt tagatatcgt tagtatttca catttataac
      181 aattattaat gagattaata tatttattat tccttattaa aataatatcc tgctcctctt
      241 attgttataa ttttctgagg atttttataa tctttctcta ttttctttct taatccattc
      301 actgcaacta ccacactata gttatcctct aagtattcat tcatccatac atgttcatat
      361 atctctttag tagtcaaagt cttttcagga ttctctataa aaaagtttaa caacttattt
      421 tctgttggag tcaattttat tattttatct tctaacttta ttactccact agttctatta
      481 tattcctcta attttgtatt attttcatta ttatttacat atgagttcat tcttcttaaa
      541 atagctttta cttttgcgta taatatttct aaatttagag gctttattaa gtaatcgtct
      601 ccaccagaat ttaaagcatt taaaatgctt tggtcttcat ttatataagt catataaaca
      661 attggacaag tagttacatt tctaattttt ttacaaagag tccatccatc accatcactt
      721 agaattattt ctaaaaatat taaatcatat ttattgctaa atatttttcc aatagcttct
      781 tcacaattat atgctaaatc tatacttatt cctttttcct ccagaaatcc ttttagcttc
      841 tggcaattat ccttgtctcc atctattatc aatatcttag tttgcattat aatcactccc
      901 aaatatcatt attcttttat attaaataag ctattattat aaaaaacata gacttaattt
      961 tattgtaaaa acagttcctt ttcctagttc tgaatctaca aatatttctc caccatgctc
     1021 tcttataatg gatttgacaa tatatagccc taacccttgc ccttttggct cattattgtc
     1081 tctttctgta aagaatctgt caaatacctt tggtatattt tctggaggta taccttttcc
     1141 attatcagaa attttaataa ttgcaaatcc atcttcttta tccattgata aaattatctt
     1201 tccatcaaat ggagtaaagg tcaaagcatt ataaattaaa ttctcaaatg ctcttgtaag
     1261 catctcttta tttatctttg catatatttt tttctccaat acgtaagttt caaagtttac
     1321 accacatgct tgtgtatctg gcaaattatt ttcatatatc tctttaataa aattattcag
     1381 acatattttt tcactaatac caatgctttt atcttgtgat gtaaattctt gcaaactacg
     1441 tactctattt tgtacttcat ttgacttttg atttatagca taaagatagg ttcttgtctc
     1501 ttcatctaca tgaatattac caacctttat caaatctata aatgcttgta tagccgaaac
     1561 aggtgccttt aaatcatgtg ctacatctgc caagaatctt ttacgttcat ttaacaatgt
     1621 tgtaagttca ttagttctca cttcaacttc atgttcaaga ttccttgtaa gtttttcatt
     1681 ctcttttatt attattctat tcctgtttat catcataaca gaaaataaaa taacaattac
     1741 aaacccacaa tattctgttt gccaccctgt aaatataggc tcaaatctat tactcgtaac
     1801 tgcatcaaat aatatgctaa ttccaaaaac agtgtttact gaaactaaaa tataagaact
     1861 tatatgctca gagcatgtct ttttatatat tgaaaccatc gaagacatta atatatatat
     1921 aaatacaata tatttatata tgtctattaa cttcccatat atgttgacaa agtacatatc
     1981 atatggaaga agaataattg gtatcactat agatatgata ctcattgtaa ttcctaatgg
     2041 taaaattaaa aatctataca ctttattttc ttctattttg gatatacttc catttataca
     2101 aataatacat aaaactacca taaaatatga caaatcttca accgcatatg taaagcttac
     2161 caaaggcagt cctaacaaat gtacaaaggg ataggataca tggatggcaa agaaaacaca
     2221 catacatcca aaatataagt aaattttact tttgtttgaa agaaaccata cagacaatga
     2281 aaatatagct attgcaaaag tcgtgaagca aattatacta taaaaaagta atcgataaaa
     2341 catcatatta cttatgtcct ttgtttctcc taatgcaggc ggataataca aaccactata
     2401 ataatgtgaa aaattcgata cattgattat aatttctgta tttttctttg caataaaact
     2461 tactactgaa tttttaattt tgggtctata tttttctgtt cctacatctc ctaatttaga
     2521 aaccatttct ccatttatcc atacttcact tgcggaaaaa atctcaggaa gctctaaact
     2581 tagtagctta tccttgcctt cattttttat tctcatacga taagtagcat tcccatatgg
     2641 tgactgattc ccctttctca tagaaaaatc tggatattga cctataaaaa catattctgg
     2701 ttttatatct tgctctgtaa aatcattcgg tttaaatatt ttatgattat aaaactccca
     2761 gtcatctatc aaaaagacaa gtttaccttt agtgaaagta tcattatcta tagttaaaat
     2821 tccattactt gctctaatag acttatatgt atatttatta tcatatttat acagaagatt
     2881 taatcctgtt attgccaaca gagagactat caatacaatg agagttcctt ttagtatatt
     2941 atactttttc attgcatcaa ccacatctct ttcatagtcg tattaaataa aacaagaact
     3001 atttattaat tacagtatct cacttatggt acaaacttat atccttttcc ccatacggtt
     3061 tgaatgtatt gatgctccct gcttaaagaa ttaatttttt ttctcatctg tgcaatatga
     3121 acctgcactg tatgttgatc tccaatatca ggcattttcc aaacttggtt atatatctct
     3181 atcttcgaaa atacttgttc tttgttttca gctagaaaca ataatatttc aaattccata
     3241 gtagttaaat ctatactttc tccatcaaaa gttacttttc ttgaatttac atttattact
     3301 aacgctgaaa actttaacac attaggaact gatgtaatat ttttgtactg cctcatacga
     3361 gcatatattc taagttcaag ttcttttaaa ctataaggtt ttgttatata atcatccccc
     3421 ccagctaaaa atccccgaac tttttcttct tcatgctcat aattagataa aaatattata
     3481 ggtatgttaa ccttttcttt tatatcattg cacattttat atccatctat atctggcaat
     3541 gaaatatcca aaattataca gtctaaaact atactctcta ctatatccat agcatcttta
     3601 gcagtctctg atgtatatac attaaaacct atattagaaa aataaatttg atttatgttt
     3661 aaaatatcaa catcatcatc tacaaccagt aaattataca ttacaccact ccattcaaag
     3721 gtattttaat tataattcca agttttatag ttattacaaa ttataatgtt ttattttcat
     3781 atataactgg tattattatt ttataatatc tttacaaact agactataat acttaagtat
     3841 ttttgaataa ttcttgaata ttgtattaaa cattaagatt cattattaaa tactaattaa
     3901 agtctccgat tgttggagaa tggagcttaa agtcattttc acgtataaat ttattatttt
     3961 tctagaaact tgtctattgg ctagtttgag tattgattta tatgatttat atggttataa
     4021 tataaaataa attgtattat tttggtaaat atattgttac aaaaggttta tattctgcat
     4081 ctcaatgttt ataaaaactt tattttctta ttataatact attattcttt taaaaaaatt
     4141 tcccttttcc aacaaatggc tactttaaaa gccaaaattt tacctatcaa taaaaatctt
     4201 aacgactaat actcttattt tcaaattttg caacatattt gttaatttta aaacaaaaaa
     4261 agactatgca atataaaaat tatattcata gccggttgca ccactaactc catatatctc
     4321 tagatgccca ataataagat atacttctca gtttctaaaa tatttttatt aaaaatcttt
     4381 tatatatttt cataaatttc ttttttattc taacattgta atattatttt gtcaatattt
     4441 ccatattctt agagataaga tactaaaata cctattttat ctaaagatat ttatatttct
     4501 acattcaata atagacaata ccctgcaagt taaagcatca tttttatgag cttatctcac
     4561 agggtattat atgtttactt tatattataa ctcttgttat tgattaactt taataaatcc
     4621 tttttctgaa acaagtgctt gtccttcatc acttaatata taatctatta aagctttacc
     4681 tttttctgac aaaccatctt ctttattaac taatataaat ggtcttgata ttggatattt
     4741 attagctatt acatttgcat cagttgcttc aacatcattt atttttaaac tatttacttt
     4801 ctcatcaaca tatccaaatg atatatatcc tatagcattt tcatttcctt caactgtagt
     4861 ttttatattt cctgaaccat cacttatttg tgcatcttta gttagttctt ctgaatcaaa
     4921 ccctacaatt tcttggaatc catctctagt tcctgaacct tcttctcttg atactattac
     4981 tattggtgca tcatttcctc ctacttcttt ccagttagta atctttcctg tatatatacc
     5041 tttaacttgg tccattgtca gattttttac tgagtttgca gtattagtta tcaatgctat
     5101 accatctatt gctattttag tttcctttaa tccagcactt ttttcttcat cttttaaatc
     5161 tcttgaactc attcctattt cagatgttcc ttctatagca ttttttatac ctccagaaga
     5221 accaatctgt tgtacttcta cactaacacc ttgatttttt tcttgaaact tttctccgat
     5281 agtttccata agaggaccta ttgaagttga acctgaaaca gaaactttgc ttgaatctcc
     5341 tgaatcacct gaacctcctg agttagaact acatcctact gctaaagctc caactaacat
     5401 tgtactagct aaaagaacgc ctattttctt tttaaacatt ttacttaccc ccgcttatat
     5461 tttaattttt tgttgtcatt tttctatatt ttaataatac agattctttg ttaaatgaat
     5521 attagagcag ggttaagtaa atgtaaatat tgttaaatac atgtaaaaac ttaattttat
     5581 atgatttatt cttaattaga ttaacttttt aaagttactt taggcagata taaacataat
     5641 acaactcata ttattagaag tcttcattga agctatcaac ctatcacatc ctataattct
     5701 ttttctagtt tattaactaa ttcagcaaat acatttaagg cttcctctat agattctttt
     5761 ttcgtcatat ctacaccagc agattttaat tgttctagtg ggtattctga ccctccactt
     5821 tttaagaagt ttatatatct atctactgca gtacttcctt ctgaaagtat ctgttgactt
     5881 aaagcacttg cagcagaaaa ccctgtggca tacttatata catagaagtt tgaataaaaa
     5941 tgaggtattc tcgcccattc tattcctatt tgtttatcta ctattgcaga ttttccgtaa
     6001 tacttttcat ttaatttgta gtatatatta gtaaattcat cagcagtaag tggttctcca
     6061 ctctctaccc tttgatgtac aattttttca aattcagcaa acatagtttg tctatgaact
     6121 gtagttctaa attgttctaa ataataattt aataagtata tagtttcatc cttagactta
     6181 gaattttcta ataaataatt tataagaagt aattcattta atgtagatgc aacttctgca
     6241 acgaatatct tatagtccga atataaaaat ggttgacttg ttcttgaata atgactgtga
     6301 acagagtgcc ctaattcatg aattaaagtg aatagagaat taaggtcatt tttatagctc
     6361 attaatatat aaggatgtga atcataactt ccccaagaat aagctcctcc ttttttacct
     6421 tcattatcat atacatcaat ccacccttca tcaaaagcac tttttatgac cttcaagtat
     6481 tcttctccta aaggtttaag tgcctctaat atgatatcct gtgctttatc atatggtata
     6541 tccatgtcaa atttatctgt caaaggaaca tacaaatcat acatgtgtat ttcattcaat
     6601 cctaaaaatt tctttttaag ctcaacatat ttatttagat taggaatact tttatctata
     6661 gctgatataa gattattgta aacatctaaa cttacatcat ctgaaaataa agacgcttct
     6721 attgctgaat tatactttct agtttttgcg taaaatatct ctgattttat tccaccataa
     6781 agcgttgagg caaatgtatt tttatatttc tcatatgttg aaaattcacc ttcaaaagcg
     6841 tcttttctaa ctctactatt cttacttttt ataaataaag agtagtttga atgagaaagc
     6901 ttaaccttat tcccctcctc atcttctatc tcaggaaatt ccatatctgc atatgctaac
     6961 atatcgtata cattttctgg aattgtcgat aattctgatg tagctgcaag tatttcttcc
     7021 tctcgttcac tcaaagtatg tggtttatct ctcaatatat cctttatata ttttgtataa
     7081 aaggatagct tctcatcttt taagtattca cttaacttat tctcttctat cgccagtatt
     7141 tctggaacta tataagaagt agccacacct aaatcagtag ataacatttc tgtcttagtg
     7201 gctcttcctt gattatcatt aattctagta tcttcatgtt gtttcatatg agtatataca
     7261 tataaatttt gaacaatcct agatgcattt tcagagatat ttaatacttt atataagttc
     7321 tccttactct cagaaagctt ccctttatat tcttttactt cttggataag attttttact
     7381 ttacttatgt ctttttcaat ttcctcttta ctggagtaca tcttatctat cttccatttg
     7441 tacttttctt ctattgtact tctatcagtt cccatatcat acacctctat tttaatttgt
     7501 tttatatttt attcacttta caaaatatat tgtatatatt ttagtccaaa taatctacat
     7561 ttattactcc ttctatcata tttatttctt tcataacgtc gtgtaagtgt attctcttag
     7621 cataagatac aaaaaaatta accttccagt attcttcatt acgacattct atttccatat
     7681 ttcttacgat aagttgattt ttttcaaatt tatcatataa aaaaggtata gagtccaaat
     7741 tgcttaattt taatatcaat acattctttt cttggctaaa taaaaacgta ttgattatcc
     7801 taagcacaaa taatgctatc attacaaata atccacctag aattgccaat tcataataac
     7861 catatccaac tgctatacca atacatgcag ttgcccacat cccagcagct gtagtaagcc
     7921 cttttactcc acctttattt tttaaaattg ctcctgcacc taaaaaacca attccagata
     7981 atacttgagc aggcattctt gctgggtcag catttgtata caaattataa tcaaagaata
     8041 attgaatcga agttattgaa acaatacaag aacctattgc aattagtata tgtgtcctaa
     8101 atcctgcaaa ctgtcttatt ttttctctct ctaagcctat tattcctcct attattagtg
     8161 ctaatagtaa ccttattgct atctccttac ttcctatatc aatcataata taaaaccctc
     8221 ctgacttaat tacaacttat gtcctacaga taatttacac atcagaaata ctattttata
     8281 tcttaatatt attattaata tatgtaaaat atagccatct gttaattttt gatacaaaaa
     8341 aacccacaac tgtgggctat ttgcttaggt acatgtattt atttattaat atatctattt
     8401 tcttacttga ttctactaac tcttcttgaa atatttctgg atattctatg tatgtattta
     8461 tctcttccct aactgcttca atctcatttt ttaacgcttc taattcattg ttcgccataa
     8521 taatcaccac tattacaaat ttgtatattt ttatatacat tttatcaaac aatattatat
     8581 tttgtcaata ttatgtcaat aaaacttact ataaaaatgc tttaatttag gtattgtata
     8641 cctggatact aagcctacaa acataccagt tactaatgat gccattaaca taaatggtaa
     8701 gtaccctata gcaagtatat tttctatgat taaacttgca actattaatt gacctatatt
     8761 atgccctatt gcacctataa tgcttatccc tattagtgat aaatctttta ttttactcgc
     8821 taaatacata aataaaagac tcagataagc tcctcctata ctaaatagta gatatgataa
     8881 agggcctgca aatattgatg acaaaattac cctgatagta acaattataa cagtatcttt
     8941 gacacctaac aacattaatg aaattaaagt tataatattg ctcaaaccca attttgcccc
     9001 tggaaatata actataagag gatttggtat atatgtctct aatacatata aagctaaact
     9061 ataccctatc ataagaccta aaaatgtcat ttttctagtt ttcattaagt taactcctcc
     9121 aaattttatc tatcatctta cattataata caaaatatat aaaaacacct aatttagact
     9181 aaaatatttt taatctattt agaataaata ttagttattt caatgtgcaa ttacctctat
     9241 aaatcttgac tttttgtatc atacttgtta caattttaat gataatgaat ttcattagga
     9301 ggtgttaata atgactgttt acgatttaaa aataggagaa aaaggattta ttaatagtat
     9361 agatggagat attaaattat ctaaaagatt gcttgcactt ggatgtataa atagtactga
     9421 aatagaagtt aaaaaggttg ccccacttgg agacccaatt ataattagat ttagaggctt
     9481 tgaccttgcg attagaaaat ctgatgctaa aaatatttct ttacaataat agaggaggag
     9541 ctacccgtga ttaatgtagc attattagga aacccaaatg ttggtaaaac tactgttttt
     9601 aatctactta caggttcaaa tcaatatgta ggtaactggc ctggtgttac tatagaaaaa
     9661 aaagaaggat ttcttggaaa agagataaag gttgtcgatt tacctggtat atatgcaatg
     9721 gatactttct caaatgaaga aaaggtttct aaatcatatt tagaaaatga agatgttgat
     9781 gtaatagtaa atgtagttga tgcttctaat ttatcaagaa acctttactt aacaactcaa
     9841 cttatgcaat ttaacaagcc tatagttata ttgcttaata tgttagacat tgcagaatct
     9901 aaaggagtta atatagatgc caaaaaatta agtgaagaac ttggagtaat tgttgttcca
     9961 attatagcaa aaaagaaaaa tggtgttgat aggatagaag aagagattaa gggagctacg
    10021 caaaaagctt ttatatatca gaaaaacttt ggaagtgaaa cagaaacata taaaaaatta
    10081 gaatccattt tatcaagatg tacaaaaact acatatacac aaaagaaatc tatcagtgat
    10141 aagatagaca atatagtctt gaatcctata ttagcatatc caatatttat tggtgtattg
    10201 ttcctcttat ttaaatttac ctttgactgg gtcggaggtc cactacaaga gggatttgct
    10261 aatcttatag aggcttatat ttctgcacct gttagtgata tgttatctaa ctctagccca
    10321 tggtttaaat cacttatagt tgatggaata attggaggtg ttggtggtac tttaccattc
    10381 ttccctttaa tatttacatt attctttggt atatcgttgt ttgaagatag tggatacatg
    10441 tcaagaacag catttttaat ggataaagtt atgagaaagg ttggtctatc tggtaaagct
    10501 tttataccta tagttatggg tatgggatgt tcttctccag ctataatggc aactagaaca
    10561 ttggaaagcg aaaaagatag aagagttaca gctcttattg caccacttat gacttgtgga
    10621 gcaaagctac ctatatatgc actatttgta gctatattct ttccacataa tgctgcttta
    10681 gtaactacat cactgtattt ggtgggtata gttatggcaa ttgtagttgc attattctta
    10741 aataaaacag cctttaaaac agaggctgaa ccatttatat tagaattacc agaatataga
    10801 atccctacta tagatgcact tattaaaaat acttggaata aatcaaaagg tttcttgata
    10861 agagttgtta ctgtcatgtt tgcaatgtca gtcgtaattt ggggactttc ttcattcaat
    10921 gtttttggat atacagaaga tataaatgta agcttcttgg ctactctagg tcatattata
    10981 tctcctatat tcaaacctct tggttttgat gattggagaa cttcagttgc tattttaagt
    11041 ggtcttggag caaaagaaat cgtagtaaac tctttaaata tactatatgg taatctaact
    11101 gttgtcttac caacaatatt taatggagtt actgcatata cattcttgat atttactgct
    11161 ttatatactc catgtatagc tgcacttgca actatgaaaa aagaatatgg caataaaatg
    11221 atgtttacat catttgcata tcaatttata ctagcatgga taatggcttt tatagttaaa
    11281 agtataggtg gagtactatt tatgggtaat tcaataatag aagctttgat aggtggaata
    11341 attatagtcc ttgcactctt tattctgttt aataaattca agtctacaaa aaacggaaat
    11401 gtctgtagtg gatgttctat ttgttctgga tgtccaagtg ctaattcttg ctcaagtaag
    11461 gaagacagca ataaaaaaaa taatgcacac taatatataa atattttagt ttaaaataag
    11521 ataaaagtgg gtgtctcaaa attaactttt tagttcatga ggcactcttt tttatagaaa
    11581 atcaaatata ttttcatcat ttcaacagta aaaaagagct tatctagtaa aaaagaggct
    11641 tatctctatt ttgagacaac ctcttttttt gttacttatt cagtttcttg ctacctaact
    11701 tcatgtggaa cctagtatct tttggaacac ttgggtctac acctcttaat gtaggtattt
    11761 ccccacatat tagttgtata ggtactataa aattaaatgt ttgatagtaa ggattatctg
    11821 tgatatcaat ctttaaattt ttatcatttt ctgtaacatc tctacctata gcaaatacat
    11881 tttccgtcca accagaaagt acatcaatca tcttagttac tctaggttct tttcctgtat
    11941 ctagtataaa tatagtagaa tcactattta tagcattata tataccatgt ataaactctt
    12001 caaactcata cccagttaca ggtattctca ttgtttccaa taattttaat gctgcttcta
    12061 atgtatctcc atatatatca gagtgaccta ttattcttat ttctttagaa ttaactaact
    12121 tttctttgtt tctttcaatc cattgtttag agagcttata cactgcttca aatctattaa
    12181 ttgcatctaa tatcttattt atttcctcat tgtacttttc actagatatt ataccttttt
    12241 ctctagctat ttgaagacct aataacatta agtttaactt tgtacaataa tatccttttg
    12301 ttttagctcc agatttttct tcaccacaat ttactgttaa tatataatca gaaatctcat
    12361 ctattaaagc attcttacaa cctgccatag atgctatttt acagccctta tcttcagcta
    12421 acttcatagc gttgtatgta gaataactac tcccaccttg agatacacct actactaggg
    12481 tattttcatt atcaaacttg aatgtatctt cagttatcat aaatggatac attttcacaa
    12541 catctatatc taataaattt tgtaaatatg gttgcacttg cactcctgag tgatagctag
    12601 tacctgaacc tgttattata atctttttta gatttgttct cttaacttca ttaaataagc
    12661 tatctgcatt agatataatt tctctcattc taactggtgt ttctaacata taatcttgta
    12721 ttgtcatttt atacaccttc cttatctata tattcaataa attataatta atttctataa
    12781 caaacctata gcatgtaaag cgattcctgt tactatagtg cctatagtta attttgttac
    12841 acttaccttt ctctttaaca tgtagtatat tacaaatgca aaggttaaag gtaacatatt
    12901 aggtattatt ttatctagta tatcttgtaa aattacttct gcaccattta agttgaattt
    12961 cagaggagta gttatactca acatagttgc aaccattcct cctacaacga ataaaccaac
    13021 agttgtagcc atagacatta ttttctccat aagtccctct ctttgtattc tttcaagaga
    13081 atttacccct acttgataac catacttaag tccaaatatt ctaagggcaa atgctggtat
    13141 attgtataat agtaagaata atagtggtcc aaagatatta ccttcttttg caagtgatac
    13201 tcctactcct gctgctataa tcctaaatgt tccccagaat aatgaatcac caattcctgc
    13261 aagaggtccc ataagagctg ttttaacagc actaattgaa ctttcatcaa attctggatt
    13321 attagcattc tcttcttcca tagctgctgt tatacctaat atagcaggaa ctactactgt
    13381 cgttgtatta aaaatctcca agtgcctttc tattgctttt gcttgatttt ctttcttatt
    13441 gtatagcttc tttattgcag gtaacattga ataacagtaa cctaagtttt gcattctttc
    13501 gtaattaaat gcaccttgaa gagcaaatga acgccaaaac atacttctta attctttttt
    13561 tgttaattta ttcaaagtca atctctcctt ccgttaaagt attgattgct aattgaggat
    13621 tttgattatt ttctttgtta ttgatataaa agtttagtac aaatgctaca catactccaa
    13681 ataaagctat agcagttata tctaatccac cataagatgc taacaaaaac cctataaaga
    13741 aaaatacaga catctttttt gaaagtaaca tatccataag caatgcaaaa cctactgctg
    13801 gcaacaatgt tcctgcaaca cccagtccgt ctaatataac tttaggtatt gcatttatta
    13861 atgctgtaac tttatcagca ccaatcataa ttgctaaaaa ggttggaact gatgtactta
    13921 aaaagaataa tattactggc aaccacatca ttatggtaac tttcttaaaa tcagcctgtt
    13981 tagcatagaa aactgccttt tgagaaaagt acgaatttat tattctaact aatactccaa
    14041 gagattgtgc taagactgct actggtactg ctactgctaa agcaacttct gcaccattac
    14101 ctgataatat agcaaaagct gtacctaata cacctcccgt tactacatct ggaggagtag
    14161 ctgcacctat tcctgcaatt cccatccaaa ttaattcaag ctgtgcacca atcataattc
    14221 ctgattttat gtctcctaaa actaatccta ctaacatacc tgtaactatt ggcctatcaa
    14281 gcatagattg accaaatata cgcccatcta gtataccaac tcctgctata atagctaaca
    14341 tagtagcttg tactaacata ttgaacctcc attttaactt agtttaattt acattaaatt
    14401 acattacatt tttgattttg ttttgatttt ctaataactc atttacataa acaattccat
    14461 tttttgcttc ctctaatcct gatttaacta ttaattttgt atcctcctca actaataaaa
    14521 gtatagataa aagcattggt aaatttactc ctgtcaataa ttcaaatttg aacccttgta
    14581 aaagtaagtt tgtacatatg tttgccacac ttccaccaaa aacatctgtt aagacaacaa
    14641 attcttcact atctttatta tttgataata tacttctaat ttctttctca gcatcatctg
    14701 ctgatttatc cgttgtcata caaaaatact caatattagt taatgaacca attattaatt
    14761 tacttgtgtc aacaagctct ctggacaatt ctccatgtgt tgcaattaga aattttttca
    14821 ttctctttct cctaaattat tttattaaat ctgatagttg tttctttttg tctctaggta
    14881 acattctaaa ttctatatca atccctaaat cacctatttg tttaaagtta tttatatcat
    14941 catcatcaac agcaactaaa tctgtaagtt tcttcttccc ttcctcatat cttaatcctc
    15001 ctacatttat ttcttttaat actcctcctg aatttttagc tacaactaaa gcatctttgg
    15061 tattttttac taacactaat acattgcttt tctttgaaga agcaaatttt tctactattt
    15121 ctccagattc ctctaccccc cttatatata aagttacatt gctaggtttc gctaagttca
    15181 gtgacatagc tttcatttgg tcattttttg cttcatcatt tgcaactagt attacattta
    15241 tacctagtga tgttgcccat ccatatgcaa cctgaccatg tatcaatctg tcatcaattc
    15301 tcatcaaaga taccattttc cccaaatcct ccatcataca ttaaaatttt tattgtttat
    15361 actctcattt atctataaaa gcaaaaagta tgccaaatac tggcatactt ttttaaattt
    15421 cattcactta ttttgtaatc ttgtatttta ctgtggtaga ccatagataa tattataaat
    15481 atatcctatc tctgaaattg gtatttgcac actataactc ttttctagca cactaaatgc
    15541 attttttatt agttttactt cactatgatg gtttttgatt aacaaatcca tatcagtata
    15601 ctcttcaatt tcagtttgtc taactaatct ttcaatcata caacttaagt gaacatataa
    15661 agaaatcttt ttatcatttg aaagtttttt cttttgaata ttttctatag cattaattcc
    15721 ttcttctatt ctctctatta tcttttttga atctaaaata gttagactat ctattactct
    15781 aattaatgaa aaattcttta caatagaatc atttatgttc tttatttttt cattttctac
    15841 tactctgcta aatattctaa aaacatcatc ttctcctttt cctgatatta tatcctctaa
    15901 taatataaaa tctaccccat tcacatttgg attggcagtt cctactatag ccattacatc
    15961 atacatttca aaaactggtt ctttatctcc catagaaaca agactatcat aatcataagg
    16021 tattattttg acatcaacta ttccaattaa actttcggaa agtagatgtt ggatttttat
    16081 agcagtacct atccctgtaa aacaagatga tattatagca tattctttat ttttttgagg
    16141 ataatacaat tgtatattag gtttagtttc ttcatccata atttctgcaa tctcttcaat
    16201 gtttttacct tgcattaata aatttcctac ttctagtgca gaaatagtgg atatttggtc
    16261 tataaataac attgggctat ttatcttatt ctttaaatct tcatatataa gattaagaga
    16321 gcccatatca aataacacaa ttaaaccatt ctttatccta tctccctcta ggtatctaga
    16381 catttgtttt gatacatcag caatagtagc atctataggc atatcaatag ctgtaaatat
    16441 atttttaccc aacatccgat tacatacatt cgccatacta ctggcagtag catatccatg
    16501 tgctataata gtcgcattaa cttgattaaa tttcattctt ataattgttg atttaataaa
    16561 tataatcatt atgattgtat ctacattatt aagatacata tccaatctat tcgttattaa
    16621 tgttgatatt ttacttatta tagagtattc tttgtaactc tcttttttta aatatattag
    16681 taatttattt tctaaagctt tatactcatc agacaattga taagattcgt ccttcaaata
    16741 aagataagac gaaaatgcca atacattatt cccatcatat tttatattgt tattaacttc
    16801 taaatttcta aatatatcct gcattatcga tattataagc tccataagta cgttattatt
    16861 ttcatcatta tttgaaaaga ctaaattgtc cattagtcta atcattagat tagaactctt
    16921 tttactaaat ttttcctttg ttatttcatt tttttctagt ctatcaaagt aatctaaaca
    16981 ttttatgaaa ctttgataga ttatatttct tttatttctt ccatttgaca tttcaatact
    17041 aaattgttta ggagaaaaga taatgctttt gcttttacca ctttggaatt gaaatatatc
    17101 tacattttct atataaagat ttctaggaag gtcttgaaga gtaacaaaaa tatttccatt
    17161 tcttctttga ttttttgcat aagctcgtcc acatgcatat tttattacat ttttacattc
    17221 acctatattc cccttgaatt ttatctttaa aatcgcattt aatgtaattt gagttatctc
    17281 tataggcaaa ccaagtacct tactttcttc ataaataaaa tgttctacaa tctttctttt
    17341 ttcaatagtc cctctttctt ctatattggg aacataaata tttatgggta ttcttcttaa
    17401 aaaggtttgt aaaaattcag atagactttc tgttgtagca aatattaatc ttaccctagc
    17461 ttttctaatt actccattct ctccaatcct agaaaacgta cctgtatcca taaatgtaaa
    17521 taacttttcc tgaccttcac tatttaatct atgtacttca tctaaaaata aaacaccacc
    17581 atctgattgt tctattagac ctgctctaga ttcatttgct ccagtatatg ctccttttac
    17641 atgcccaaat aatagactag acaataactc caaattatta taatactgcg cacagtttaa
    17701 cacattgtat ggagaatttt tttctaatac attactgctt acactatatt tgtatattat
    17761 cttggctaaa aaagtttttc ctactccact ttcacctgtc agcattattg taagtccgcc
    17821 atttggataa agtacagcgg tttttatttg ttcgattact tcttttaagc tattatcata
    17881 tcctatgata ctattaaaca cagtctcttg ctttaataat ttacactcat ttttaagttc
    17941 atctaaattt tcataaatac ttttttttgt aggtcctact acatcattta ttttattttt
    18001 aggtaaaaaa ataacaggtc tactgtttat ctttataaga ttatcagatt ttactaaatc
    18061 atttaataat ctacttgatt gagttctact taaattaaac ttttttacta tatcttctgt
    18121 tactatgcca ctttcttttt taagttcatc aaagttgtta aataatacac attcatttat
    18181 aaaacttaaa atttcatccc tcatgttcaa cctccaatac aaatatcaat aatactataa
    18241 tattagtata tcatttatat atttatgaaa aagataatta tattcctatc ttgagtctct
    18301 tttgtaaggt tggaaaatca aactttttat aagtataaaa tctagttttt ttaacataat
    18361 ctcaagattc ttattttccc atatatttga tatagaattt atataagaat atatttattg
    18421 tatttattat aataaaaagt aaaacattat aggtatttta aaacttatta gcgaagaaaa
    18481 tatttgtaac ttttattacc ttatgaatat tatttcaaat ttaaaaaggc tataaataaa
    18541 tttattttta aataaatcta cttataaccc cacaataata cttataaatt ttattttttc
    18601 acaatgatat atctcaaata tagttaaaaa tatatctatt taattattaa tatttaagta
    18661 ataaattctc actcaatcat taaattcctt tttatagtaa attactctta ttttacttat
    18721 accaaataca tttatgtata gatataaata agcactaaaa aaacaattca agaaaccata
    18781 tagtaaactt aattacatct gttatttgct catatcttta gacttatcta tacaagcaac
    18841 aatagatttt ataactgctg ctctaaagcc ttcttcttct aataccttaa cagcttctat
    18901 agtagttcct gctggagaac aaaccatatc ttttaattca cctggatgtt ttccagtttc
    18961 aagaaccatc ttagctgacc ccattactgc ttgagatgca aatttataag cttgttgtct
    19021 tggcattcca gctaatactg ctgcatctgc catagcttct ataaacataa atacatatgc
    19081 aggagaagaa ccactaatac ctgtaactgt atccattaaa tattctgata ctatttctgc
    19141 ctcaccaaaa gattcaaaca gagccttaat catatttaat tcttcatctg ttacattact
    19201 atttttacaa agagctgaca ttccctcacc aacaagggct ggagtattag gcattactct
    19261 tactattttt ttatctgaac ctataaaact ttccaaactt tctatagttt tacctgctgc
    19321 tatagatact attattttat ttgcatctat taattcttta agtggagtta aagccttttc
    19381 gcatatatta ggtttaagtg ctactattac cacatcagaa tttgtaacag ctacctttga
    19441 atcagttgta gtatttactc caaattcttc ttttacttta tctaaggcaa cttggcttaa
    19501 atctgataca gttatatctt ctgcctttac taatcctgac tgtactatgc cacctatcat
    19561 tgcacttccc atattccctg aaccaataaa tcctaaagtt ttcatatcaa atctcctttt
    19621 ttctattagt tttattttaa agtagctaaa ttgactttat tttaactgct taaaattatc
    19681 ttatttttat aaaatataac cttattataa ctataataaa ttattctttt gtatgtatta
    19741 cttactaatt atgtgtatga tttactaaat ataaatttaa cgattttttc attaaactta
    19801 acgagctaac ttcctattta gaaagttagc tcataattaa tctaaaattt taaaaatgga
    19861 atcaaaccat ttatacttta ttatatcagt tacgatttta tatagtaaga agttttattt
    19921 acaagcaaac ctagaatgtt tgctcagttc ttcctattat ctcatcttgt agtgttctac
    19981 ttaaattatt gaaatggtca ctatatcctg caactctaac tattaagtct ttataatcct
    20041 gaggattctt ttgagcctct aacagtacat ttttatcaaa tacattaaat tgtatatgat
    20101 gaccatccat attaaagtat gctcttacta gattagccat attatctaac cctttttctc
    20161 cttgaactac tgatggtgca aatctttgat ttaataatgt tccaccagtt tttatgtggt
    20221 ccatcttagc acaagatttt ataactgctg taggtccatt agtatctcca cctttttcag
    20281 gtgaaattcc ctctgaaact ggttttgcac aaagtctacc atttggactt gctcccataa
    20341 tttctccaaa gtatatatga caagttgttg gtaacatatc tactctgtat tctccaccac
    20401 aaacagttgg tctaccagtt acctcattgt aatatgcatt gaatatctct tgcattattt
    20461 catcagcata atcatcatca tttccatatt taggagtctt atttgaaact aaattaagta
    20521 tagcttcata tccttcaaaa ttagcatcaa gtgctttaag caatgtatcc atatcgaatt
    20581 ttttcttatc aaatacatta tattttattg ctgttaaact atctgttata gttcctatac
    20641 caacaccttg tatatatcta gtgttgtatc ttgctccacc tctttggtaa tccttgcctt
    20701 tttctataca atcatcaact attgtagaca taagtggaca aggcatgtgt tttgcacata
    20761 tattttctat cacagcattt ccttctattt ttatgtcaat catataatgt aattgctttt
    20821 taaatgcttc aaatagttcc tcataagatt ggaaatttct agtgtctcca gtttcaatac
    20881 ctatttgttt tttactaatt gggtcatatc cattatttaa tgttaattca agtatttttg
    20941 gaatgttcat atatccagtt agaacatatg cttctttacc aaaacatcca gtttcaacac
    21001 aaccactggt tccaccaagt cttgcatctt ctatagtttt tccagcttcc ataagctctt
    21061 gaactattgc ttcagtatta taaaatgctg gttgacccca tccttttctt gatatttcac
    21121 aagctctctt taagaatttt tgaggagtct ttttacttat ttgaacattt gaactaggtt
    21181 gtatcaattt catttcatcc ataacatcaa gtattatata actaacttca ttaacaccat
    21241 cttgaccatc tggatttatt ccaccagtgt ttatatttgc aaaatctgta tatgtgctac
    21301 tttcttttaa tgttatacca acttttggtg gtgctggctg attgttaaat ttaacccata
    21361 aacattcaag taattcttgt gctctatctc tatctagtat tccattttct acatctcttt
    21421 catagaaagg atttagatgt tggtcaagtc ttcctggagt aaaagcatcc catatattaa
    21481 gttcagtagt aacccctata tgaacaaacc aatacatttg tatagcttga tgataagttt
    21541 ctggtttgtg agctggtaca acatcacaag tttcagcaat tagtaataaa tcttgtttct
    21601 tagcttcatc tgtttcttct tctgccattt gtcttgcttt ctcagcatat cttttaccta
    21661 atataaccat tgcatcacaa gctattgcca tagcttctaa atctgctttt ttattatatg
    21721 catctaaatc attaagaaaa tctagctctt ttaatcttgc ttctatgtct ctctttaaat
    21781 ctaaaaatcc ttttttatat attgtatctc cacaaactgt atgtcctggg gctctttgtt
    21841 ccataaactc tgtaaacata cctgcttcat atgctgctaa ccactcaggt gtcattgcat
    21901 ttattatctt atctcttgtt tgtctctttt tccaaaaagg aattatttct tctttatgta
    21961 tttttctagc ttcttctgat acgctaaaat ttattatatc tctattgtgc attacttcta
    22021 aatcttccat tgtatgacaa caaatttctg gatatgttgg tgctccatta ggagaatcac
    22081 ctttttcacc tactattaat tctccatcat ttatgctaag agttctattc tcaatataat
    22141 gcttaaatga taaagcacga agtacaggaa tctctacact tccctcatat tttttataag
    22201 cttctgtcat aagtactgct ctttcaatag atatgtgtgg ctctgcatta atactttctt
    22261 ctcttaattt tttagttctc tcaaaagttc ctcttgccat tttattaccc tccaatctta
    22321 gtattgaaat tacttgcttc aaacagtctt tttatttcct ctaatttttc ttctgatggt
    22381 ctttgtagtt cttctccttc atacttttta taaattttat catacttgtg tttaccaata
    22441 ttatgatatg gaagaagact tactgcttgt atattcaaag gctttaaaaa ctctatcatt
    22501 tttttaacct ctaaattttc atcatctaca tttactccta caattaatgg tattcttata
    22561 tttatgttag cccctaattc acttaaaatc ttaacatttt tcagtattaa gtcatttgat
    22621 tttcctgtaa attttatgtg cttatcttca tcaataagct taatatcata taaaaacaaa
    22681 tctgcacatt tagcaactct ttcataattt tctgactttg catagccaca tgtatcaatt
    22741 gctacatgga ttccctttga tttgcacatg tttattactc cacaaatgaa gtccatatct
    22801 tgagccatta cttctccacc tgatagagtt actccaccac ctgattcttc atagaaaatt
    22861 ctatccttct ctatctcttt aaccaaatct cttacagaat actcttgacc aacaatctct
    22921 cttgcattgt ttacacaata gtctaagcaa gtttcacaaa actcacactt atcttggtct
    22981 aagcatattt ttgtttcacc tttgtaaatt gccttatgag ggcatatatt tatacatgct
    23041 tcacattttg aacatctttc ttcattatac aaaacttgtt ttgtatatgt ttgactctct
    23101 ggattatgac accaaacaca ttcaagtgga caccctttaa aaaatactgt acttcttatc
    23161 cctggaccat catgtatgct acatttttgt aagtttataa ctaatggatt catgattttt
    23221 cacccctaaa taatatccat tccatttttt catttttatg caattcatct tcatagaata
    23281 tacctatgaa aagcatttct acaattacat aatactatat ttgttattat tttgtctata
    23341 tgtttttagt aatattaaaa aattttat
//
LOCUS       DAEPXW010000060        23211 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.061, whole genome shotgun sequence.
ACCESSION   DAEPXW010000060 DAEPXW010000000
VERSION     DAEPXW010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23211
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.061"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(190..558)
                     /locus_tag="KRM55_002365"
     CDS             complement(190..558)
                     /locus_tag="KRM55_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1594602.1"
                     /translation="MKKIPKSELLVMNFIWDKGIDKIPAREVANYMEISHGWTKGTTG
                     KVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISSLDC
                     GNEISDDDIKELEQWLKKRK"
     gene            complement(1086..1508)
                     /locus_tag="KRM55_002366"
     CDS             complement(1086..1508)
                     /locus_tag="KRM55_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBH1594603.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALIRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            1986..4889
                     /locus_tag="KRM55_002367"
     CDS             1986..4889
                     /locus_tag="KRM55_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1594604.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            4922..5368
                     /locus_tag="KRM55_002368"
     CDS             4922..5368
                     /locus_tag="KRM55_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1594605.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            5491..5793
                     /locus_tag="KRM55_002369"
     CDS             5491..5793
                     /locus_tag="KRM55_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1594606.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            5974..7380
                     /locus_tag="KRM55_002370"
     CDS             5974..7380
                     /locus_tag="KRM55_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH1594607.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            7724..8782
                     /locus_tag="KRM55_002371"
     CDS             7724..8782
                     /locus_tag="KRM55_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1594608.1"
                     /translation="MGDKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCRKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEENILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            8881..9567
                     /gene="araD"
                     /locus_tag="KRM55_002372"
     CDS             8881..9567
                     /gene="araD"
                     /locus_tag="KRM55_002372"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBH1594609.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            9585..10232
                     /locus_tag="KRM55_002373"
     CDS             9585..10232
                     /locus_tag="KRM55_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH1594610.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GIGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(10405..11772)
                     /locus_tag="KRM55_002374"
     CDS             complement(10405..11772)
                     /locus_tag="KRM55_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBH1594611.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(11962..12050)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            12478..14598
                     /locus_tag="KRM55_002375"
     CDS             12478..14598
                     /locus_tag="KRM55_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBH1594612.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            14702..15955
                     /locus_tag="KRM55_002376"
     CDS             14702..15955
                     /locus_tag="KRM55_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBH1594613.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLGKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(16109..17170)
                     /gene="ytvI"
                     /locus_tag="KRM55_002377"
     CDS             complement(16109..17170)
                     /gene="ytvI"
                     /locus_tag="KRM55_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH1594614.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            17444..18184
                     /locus_tag="KRM55_002378"
     CDS             17444..18184
                     /locus_tag="KRM55_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBH1594615.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            18196..19974
                     /locus_tag="KRM55_002379"
     CDS             18196..19974
                     /locus_tag="KRM55_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1594616.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNINSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            20141..21058
                     /gene="pfkB"
                     /locus_tag="KRM55_002380"
     CDS             20141..21058
                     /gene="pfkB"
                     /locus_tag="KRM55_002380"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH1594617.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREHIDKLVNEISVKQF"
     gene            21095..23014
                     /locus_tag="KRM55_002381"
     CDS             21095..23014
                     /locus_tag="KRM55_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1594618.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIFLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         9250 a         2514 c         3924 g         7523 t
ORIGIN      
        1 atttaatata tttaaattta ttttagatat aaacatcatt ctgactacta ttaaaagaca
       61 taaaaaataa ttaaacttaa aattatattt gcttatcttt ttagtaaata aaatgaaaaa
      121 aagaattagt ggacttatgt aaatattaaa tttaataact tctataaata attccataaa
      181 atacgtctcc tattttcttt tttttagcca ttgttcaagt tcttttatgt catcatctga
      241 tatttcattt ccacaatcta atgatgatat aaagctatga atagaatttt tatgtataag
      301 ctctaaaaaa tcctttgttt caaattttag atattcctca tgtttaactt taatagtgta
      361 taaagtattt ctaccatctt tttcaaattc taaaaaacct ttatcactta atctagaaag
      421 tactttacca gtagtacctt ttgtccatcc atgagaaatt tccatataat tagctacttc
      481 tctggctggt attttatcta tgcctttatc ccatatgaaa ttcataacta acaactcgga
      541 ttttggtatt tttttcaata taatcactca cctttaactt gattatatta gacaaatgtc
      601 taatagtcaa tataatatat cataatgtat aaataatctt tatattattt tatgcttgag
      661 aactaagtag tatagattta tagataaaaa agatgttgag agttttatgg aagaggggaa
      721 tatattttct attagagata agaatatgac atatattttt tattgatttg tacaaaaata
      781 ctatatagtg aataaattaa tatcttttct aaattagaag aggataatct tattagataa
      841 agattatcct ctttattgaa agtttaaggg atattagaga ttattaattt ttctctcttt
      901 ttttaactaa aagcaataat acataaaatt attattgcta atgatactct taatgtggta
      961 tatagtcata gtgtcacatg tttatcaata gttttttcag taattattgt aacgaatagt
     1021 aggactcata aaatacttag aaatatgttt ttagataaat tttaaatata taatctaact
     1081 tatatctata aattaacact attattctcc aattccattt ctagtttttt tataaattta
     1141 ttaaattctt ctggttgcct ttttccaaac aatactctta taagagctga attgattttt
     1201 ccaaatatat tcctcttgct ctcactttca ataaaaataa gttttgtatt ttctaagtca
     1261 atatgtacta attcatatct agtaatagta ctttctcttt tattgcttgt ttttatctca
     1321 tatactctat ttttttcgaa attagttatt tcaaccttaa atcttttatt atttttttgc
     1381 tgtacaaatg ttcctactgc ttttttctca ttaaaattag gaaaatttag tcttgcagat
     1441 tttgtaaata tattaaatat gtcttttgca gaatatttta ataaaacttc agttttaaat
     1501 gtattcatat cgttttccct tctgtatata aatttaatat ttataagtta atttttaagt
     1561 taaaatagta taatatgcca tattaaatca tgttaaaact atttatatag ctaaaatctt
     1621 acctatataa gtatgtatac tatcatataa aaataaaatc ttaaaataga aagggttaaa
     1681 aacacagttt attataattt ttattgttga gtagatacgt actattatat atgattgagc
     1741 aagtttttca atcataaatt tataaagtat tttgcattaa aatttaaaca aagaattaaa
     1801 ttatttaaga ttatgaataa ctaatacatt tagtaaatta ctaaatatac aaaatgtaaa
     1861 tacttatcaa aatgtataaa tacttatgac atctagttac ttacagggtt taagtagaaa
     1921 aaaatatcaa agtaagtatg gcatgatagt tgcttatata tttatcaaga aaggagttat
     1981 taagcatgga gttgagagat aaacttgtaa acatcataaa tacagaaaat aaaaaagatc
     2041 cattaacaga tgttcaaata gcaaagtttt taagtacaac tagagagaac ataactaatt
     2101 tgagaaaaga acttaatata agtaattcaa ggcaaagaag atatccttat ttaaaatcag
     2161 caatttcggc aatattacaa aagaataaga atatttctat atcagaaatt acaagggaat
     2221 tgatgacaga aggctttaat atatctagaa gagttgtgga ggaactttta cctaaagaaa
     2281 gtttagaaat ggatgtagta gaggaatctg aagaagaatc gaatgaccca tttgaaactc
     2341 tgataggtaa taaagggagt cttagaaatg ctgtagagca ggctaaatct gctatattgt
     2401 atccaccaaa agggttacca acgttgatta ttggggaaag tggagttggt aagagtttat
     2461 tttctagaca tatgtatgag tttgcaaagc aaaaaaagat agtaaaagaa agctccaatt
     2521 ttgttgtatt taactgtgct gattatagtg acaatccaca attattatta tctttgttat
     2581 ttggatataa aaaaggtgca tttacaggtg ctgaatatga tacaccaggt cttgtagaag
     2641 aagctgatga aggagtttta tttttggatg aaatacatag attgcctcca aaaggccaag
     2701 aaatactatt ttctatttta gataggggaa agtttaggag attaggtgaa actaatgctg
     2761 aaagaaaagt aagtattatg ttgattgggg caactactga aaatgtagag actaatttat
     2821 tattaacatt cagaagaagg ataccaatgc taataacttt gccaccatta catgatagat
     2881 tactaaaaga gaaaatagac cttatataca atatctttca acaagagtgt aatagaataa
     2941 atgcaaaaat atttgtagat aaaaatgtga ttgaaatact tgcactaaaa aagtttagtg
     3001 gaaatatagg acaattacaa aatatgattc aggttctttg tgcaagagct tttatgaagt
     3061 ttataaattc caaagatgaa gatagtgaat cgatagtagt agtagatata aatgaagttt
     3121 taaagcttaa agattctttt aaagatgctg cctttcaaga gattgaatat acagagataa
     3181 gaaaatattt gaaaaatgct atatttatac catttaattt agaagaatca tcagtaaaag
     3241 gaagtctttt aagtgatgaa tatatattac cagaggacat atacaaaaca attgaaaaga
     3301 aatattatga cctaaaatcc ctagacattg aagatataga tatagagaat attttatgga
     3361 cttttatttt aaatagattt gctgacttaa agtttaatct cgatagtaat gaagaaattt
     3421 tttcaatgag tgatttaaat agttttgtaa gtgatagttt agttaaactg gtaaaagaac
     3481 ttatgaatga tatagttgaa aaaaatatga atttagaagt aaataaaaat atgttcaaat
     3541 atctagcaat acacttagaa gaagctataa aaagaattaa gctaaatcaa aagataataa
     3601 atgtaaattt agaaaaaata aagattgact tttcaaaaga atatgaaatt agtaaaagtt
     3661 ttgcaataaa aattgaggaa tcaattggta ttaagattcc agatgatgaa attggattta
     3721 taacactcta cataaagtct gctctaaaaa atgaagtgaa aaaagataaa gtagggttaa
     3781 taataatttc tcatggacgt atagctacag agactgtaaa tgtagttaaa gaacttttag
     3841 gtgtaaagtt tcctgtggct atagatatgc ctttagatga aaaaccaata aatatataca
     3901 ataaggcagt agaactgtca aaaataatag accaagggaa aggcatattg tttttggtgg
     3961 atattggttc acttacaaac ataggtcaaa tagtaaataa gagaaccaat ataagcacta
     4021 aaactattga tagagtagac ctcctaatgg cactagaagc aactagaaaa gtttctatgg
     4081 gagaggaaga acttgatgaa atattttttt ctttgctaaa agataggatg ggatataact
     4141 atgaattaga aaaacacata gataaatcaa atgcaattat aacattatgt cttactggag
     4201 aaggaactgc taagtatata agtaaaacgt tggaagaaaa gtatgataac actaaatgtt
     4261 atcaaatgag tgcattggat gaaaatttat tttgtaaaat tgaaaatcta aaagagacaa
     4321 acaatatatt agctattgtt gggacaataa accctaagat accaggtata aattttatac
     4381 cctataataa agaacttttc aaaaatttgg atatctatct atcaaaatca aaacaacaag
     4441 atgacagacc aattaaatcg tatgaaagaa tgcttgatga ggatttagtg atttttgaac
     4501 cagatatata ttttaaaaag gatttattag aatatgtatg ttcaattctt ataaataaag
     4561 aatatgtaga aaaagattac ttagattctg ttttacatag agaagaaatg cttccaacat
     4621 attctaaagg agctataggt gtgcctcatg gagattcttc tactgtaaat agtacaaggt
     4681 ttgtttttgt taaactaaag aatcctattg attggggtgt aggtaatgta aatttcatat
     4741 ttatgccagt ttttcaggct aatgataaag agattgttaa aaatgttctt gagatactaa
     4801 aagatgcaga atttatgaac aatgccaata agtgttttga taaagatgct tttagaagga
     4861 ttatatttga taaatttaaa catctgtagc catagcaaaa aaattgagag gagttagagt
     4921 aatgaatgta gatttaatat cattgggttt agaatctaat gattatgaaa gtgttattga
     4981 agaattagga agtataatgt gtaaaaaaga atatgtaaaa gaaacataca taaatgctgt
     5041 cttggaaaga gaaaggacat taccaacagg tctagatatt ggagaaatgt gtgttgctat
     5101 tccacataca gattcaaagc atgtaaatga gtctaatgta gctgtaggga tattgaaaaa
     5161 tcctgtaaag tttaattcaa tgatagaccc aaaagataga cttgatgtag aacttgtatt
     5221 tttattagca gtaaagaacc cagattcaca agtaaaactg ttaaaggatt taatgtcagt
     5281 ttttcaaaat ataaagttat taaaaaatat aaaaaacgca tcaacaaaag aagaagtagc
     5341 taaattattg gactttatag aaatttaatg taggagaatt ttataaataa aaaattaaaa
     5401 tttaaacaat caaagtaagt attatttttt taataggttt aatcttatat aaaataaaaa
     5461 tttagagtga aaaattagga ggaaattatt atgaaacaat ttaatgtatt atcagtttgt
     5521 ggttcaggga cagttacatc atctatggta gcaggtaaat taaaagaagt actaggtaat
     5581 aaggggattt ctattactac aacagaagct agaccaacag aagcactaaa tttagcacaa
     5641 tcaggaagat ttgactttat aacatttacg agtccacttc aaacaggcga ttatggaata
     5701 ccaactataa atgcatttgc ttgcctaact ggtatagggg aagaggcatt ctttgaagaa
     5761 gttttgactg ttattgaagg gatagataag taagttttgg agacgtgaat ttatagtatt
     5821 taaatcaatg atttagatac tataataagc taatattaac taaatatttg tggaaaaaac
     5881 attttatatg ttgtcataaa ttaaaaaatt ataaaaatag tcacttaagt attaaattaa
     5941 gcttataaat atttataagt aggagggaaa aagatgttag aatttatgaa atctataatc
     6001 gatacatttg gttctgcaat tatagttcca attataatat tcataatagc aaagatattt
     6061 aaagtaacta ctaagaaatc gtttctttct gctgtgtatg caggagttgc tttacaaggt
     6121 tttacactga ttttaaattc atttacacca ataataacac cagttatcaa taggatggtt
     6181 gagagtacag gagtaaacct accagttttt gatgttggtt ggcaagcaac atcattggtt
     6241 gcattttcaa caagtgcagg tatgatatat ttaggtcttg gtatattatt acaaacaatt
     6301 ttatttttga taaaatggac agacgtgttt caaccatcag atttatggaa taactattct
     6361 tatatggtat ggggagcaat ggttatagga gtaacaggaa attttccttt aggtatagca
     6421 tgtatggttt tattaaacct atatagttta ttaatatcag agttagttgc aaagagatgg
     6481 tctagttact atagatatcc taattgtaca ataatagcta tgcataatgt tgaagcttct
     6541 gtgtttgcag tatttgcaga ccctatatac aataaattgg gattaaataa aataaaatta
     6601 aatccaaaag aattagagaa gaaattaggg tttttaggtg aaccaattac tttaggtctt
     6661 tttttaggta tgtttatagg tatattaggt aatatgacga gaataaatac tatggaagct
     6721 tggggagaaa taatgaaagt aggtatatct acaagtgcag tgatggcaat tttccctaaa
     6781 gtagcaagta tgtttgctca agcatttgca cctataacag aagcagctag aaagattatg
     6841 caaaaagctg gaaaccgtga gtggtacata gcagtaaatg atgctgttgg atatggtgaa
     6901 cctgcaactt taatatcagg tcttatatta attccaataa tgcttgtaat agctatggta
     6961 cttcctggta ataaggtatt accagttgtg gatttattgg caattccata tatggttcaa
     7021 ggtttagttg ccatacataa tggtaatata ccaaaagtat tagtttcagg tataatttgg
     7081 tttggattag gattatatgt ttgtacatct acagcaccat tatttacaga tatggctaca
     7141 aatataggtg tagctatacc tgcaggagca atgttaataa caagctttaa tatactagga
     7201 aaacctttga tgggattagt tttctttgca tttctaagtg caaatccaat ttatataggt
     7261 ctttcagttg taatttactt tgttctatgg gcattgttta gaaagaacaa aacaagtatt
     7321 cttgattatt tagaaaaaca agcactcaaa aatgtagaag aagagcctgt agcagtttaa
     7381 gtttataaaa atgaaataag aataattaaa ggagtttata attgatttta tataagtatc
     7441 agataatacc tgagaaatat ttaaatgaaa tatagacttc tttttatttg ataatatttg
     7501 taattataat gcattgtatt tttatagttg agttttctgt ataacctgct atttaaaaca
     7561 tactctttta tatttataca gtaatgtggt ttaattttat aaaatgtaat ctctactggt
     7621 aaaagacttt gtatataagg catttgcctg aataaaccat ttatcttttg tatggcatag
     7681 atattgctat atagaagtat atagcatgaa aggagatatt tatatgggag ataaaatgag
     7741 agcatcagta ttgtataatg taggtgatgt cagatatgaa atggtagata taccagaaat
     7801 aacagatacg caagtgcttg taaatgtaaa atatgttggg atatgtggtt cagatttacc
     7861 taggtctatg gtaagtggtt tgagtggaaa tacaaaatat ccattgattt tagggcatga
     7921 attttctggt gaagttgtta aaattggaga aaaagtaaag catattaatg taggagatag
     7981 agtagctgtt gcaccattag taccttgtag aaaatgtgat tattgtaatg aaggtaattt
     8041 tggcttgtgt gatgattaca atataattgg aacaagagta aatggagcgt ttgcagaata
     8101 tgtaagagtt ccagaagaaa atattttaaa actaccagat acattggatt atgaaactgc
     8161 tgccggaatt gaaccagcaa ctatagctta tcatgggatt tcaaagtcta atattagagt
     8221 aggagatagt gtagttgtgt taggatgtgg tccaataggt cagtttgtta tacaatgggc
     8281 aaaggtgttt ggtgcatcta agattatagc agttgatatt tttgatgaaa aattagaact
     8341 ttctaaactt ctaggagcaa actatatact taactcaaaa gaagtaaatg taatcaaaga
     8401 aataaaaaaa ataacaaatg gtggtgctga tgttgtaata gagactgctg gtagccgatt
     8461 tacacaagaa caatctctat ttgtagcaaa aaagagagga aatatagtgt ttgtaggtat
     8521 atcacacaca gaattaccac ttagtgcaga cgctactgag tgtatattac gtggagaact
     8581 taccttgaaa ggttcttgga attcatatac aagcccttat cctggaagag catggactgc
     8641 aacattggat tttatgggaa aaggtgacat tatttttaaa cccatgattt cacataaaat
     8701 aggtcttaat gaagttggtg actttttaag taaaatgagc aagagagaaa ttaatttcaa
     8761 taaaatccta gtagaaatat aaaaatttaa taaaaaattc taaaagcaat taaattttat
     8821 aactatgaca ttaaataaaa taaaaataat tttcttaaat aaaatatagg aggaagaaaa
     8881 gtgttagaaa atttaaaaga agaagtatta aaagcaaact tagaattacc taagaaaaag
     8941 ctaattactt atacttgggg aaatgtaagt ggaatagata gagaaaaagg attagtggtg
     9001 ataaagccaa gtggtgtaga gtatagtaat atgactgtag aagatatggt tgtagttgat
     9061 ttagagggaa atatagttga tggcaaatta agaccttctt cagatacccc gactcatcta
     9121 gttttatata aagagtttga agaattgggg ggaatagtac atacacattc aagttgggca
     9181 acaatttggg ctcaaatagg aaaatctata ccatcttgtg gtactactca tgcagattat
     9241 ttttatggaa gtataccatg taccagaaaa atgactagag aagaaatttg caatgaatac
     9301 gaaaaggaaa ctggaaatgt aatcattgaa gaatttatgg gaagaaatcc aattcattgt
     9361 ccaggaataa ttgtaaatga ccacggacct tttacatggg gaaaagatgc aaatgaggct
     9421 gtacacaatg cagtagtttt agaagaagtc gcaaagatgg cttattatac agagttaatg
     9481 agtcctgata atattatgga taaggttctt atgaataagc atttttcaag aaaacatgga
     9541 aaaaatgcat actatggtca aaaatgatta tctggaggtg aattatgcta gactctttaa
     9601 aaggtaaaat tgtggaaata gcaattaaag cagagcatta tggtttatgt aaagaaaaga
     9661 ctggtaattt tagtattaga gataaggata ctggatatat acttataacc ccatcaggta
     9721 taggaagaga agaattaaaa gttgaacata tttgtgtatt ggatttggat ggaaatgtaa
     9781 tagaagttga gaaaggtatt aagccaagta gtgaggtatt gatgcatatt gaaatataca
     9841 aaacaagaga aaatataaat gccatatcac atactcattc tttatatgca acagcatttt
     9901 cagtagcaaa gaaaccaatt ataccaattg tatatgaatc agttaattat ggcggttatg
     9961 tagatattgc tccatacgaa agaccaggaa ctttaaaatt agctaagagt gtttcaaaat
    10021 tactgataga tacagatgca tgcttattag aaagacatgg gttgacaact gtaggtaatg
    10081 atttagacga agcattatta aaatcaagat atgttgaaga ggtagcagaa atatactata
    10141 ggtctttagt attaaatcaa tttaaagaac ttgaagtagt agatgttgat gagtttaaat
    10201 cttggaaata cccagaagaa ataaagtttt aatctaaata attttcattg aagtggttaa
    10261 ttaaaatata tgtattattt atatcaatta ctatgtttta ttatattaat taccgtattt
    10321 tgtaaatata tttattacat tttttcaaaa aaatatagaa tccgaaagcc atataaaatt
    10381 gacttgggat tctatacttt ttatttatgc atttttcttt atctgatttt ctggagaatt
    10441 tatatgttca aaatattttt tagtttcaga tactattata ggtgataatg caagtaaagc
    10501 tataaggtta ggtattgcca taagcccatt tacaatatca gcaattatcc aaacaacttc
    10561 taactttaag aaagcaccta ataacaccat agccacaaat acagttctat acccattcat
    10621 gccttttaca ccaaacagaa attcaaaaca tctttctcca taataactcc atcccaaaat
    10681 tgtagtaaat gcaaataatg ttaaactaac tgtaagtaat attggtccaa atgtaggaat
    10741 tgctccgtta aaagctgctt gtgtcataac agctccattt aggtctgaac accacactcc
    10801 tgaaataaca agagagaatc cagtaagagt acagattata atagtatcta taaaagtacc
    10861 tgtcatagat ataagacctt gttccgctgg ccattcagtt ttagcagcag cagcagctat
    10921 tggagcacta cctagaccag actcatttga aaatacacca cgagcgatac catttctaat
    10981 tgccagtgac atagttgctc ctaaaaaacc accagtagca gcagtaggtg taaatgcact
    11041 tttaattatt aacataaaag tttcagggat tttattccaa aaagatatta aaatgattcc
    11101 acagattaca acatatataa ctgccataaa aggtactatt ttagtagcta cattagatat
    11161 acttttaagt cctccaaata caaccaaagc tacaaatact gctaatacaa cccctgtaat
    11221 tctagggtct atcccgaaac tattatttat tgcatctgtt attgaattta cttgagtaaa
    11281 agtaccaatt cctaaaagtg caactagtat accacttata gcgaaaaata ttgcaagagg
    11341 tctccatttt tctcccatac catttactat gtaatacatt ggcccaccag acacttggcc
    11401 atttttatct ttagttctgt attttattgc aagaacacct tctgaatact tagtagccat
    11461 tccaaagaat gctgctatcc acatccaaaa aagtgcacca ggtccaccag ctttgatagc
    11521 tgtagcaaca ccaacaatat taccagtacc aactgtagca gctagagcag tacataaggc
    11581 tgcaaaactt gaaacatcac cactaccttt gttttcagca gagaatatta acttaagagc
    11641 tcttggcagt ttagttattt gaacaactcc aagcttaaca gtaagtagta taccagtacc
    11701 aactaatagt accagtaggg gtggtcccca aataaaagca tcaactttgt ttaaaatatc
    11761 aattagattc ataaaaacac tccctcattt tttttgcttt acataatcaa tagaattttt
    11821 aatgaagtaa ttgacaggaa ataagtataa tttattaata atttctagtg taataaaaaa
    11881 agctaaatct aaaaaagatt cagctctgga tgtacactaa ttagcaacca aaataaaagt
    11941 attagtaaat actgtttttg gtagataatc cctgtccttt tgcctgagag attgagcata
    12001 aaagccttgc cccttcggcg cccataatgg gtctctccag agttccgtaa attttacagt
    12061 cctactttta aaagtacctg agagtgttac tccttcggtg tgctatatag caactcttct
    12121 ataaaatctt aaccggatat tgatttgtca tagcttattg tattaataat attaatataa
    12181 gtttttatgt tttgtcaact aaaaaattaa aaaacaaaga aaaaatataa aaatgtaagc
    12241 ctatttacga attataaact tagaaagatg agtaatatac gtgaaaatga attttgtaat
    12301 acacatacaa atgaagtgta aaataagttt taaataaaaa aataataaaa tcttaaataa
    12361 ttaattagat atgattaaat tatggtaata ttatagttac gatattaaga aaagttctat
    12421 ttagttagat tttaatcgta atatgagatt atgtatagag aaaggatgta tttttagatg
    12481 ggaaaaatat tagtgctagc agaaaaacct tctgttggaa gagatatagc aaaagtttta
    12541 gggtcaaaaa atgaaaaaaa tggttatata gaggggccga agtatgtgat aacttgggca
    12601 ctaggtcatt tggttacact tgctgacccc gaaagttatg gagaaagata taaatcatgg
    12661 agcttagaag acctgccaat acttcccaag caccttaaga ctgttgtaat aaaaaagagt
    12721 ggaaagcagt ttaatacagt taaatcgcaa atgaatagaa atgatataga tgaaatagtt
    12781 atagcaacag atgcaggtcg tgaaggagaa cttgtagcaa ggtggataat agaaaaatca
    12841 caggtaaaaa aacctataaa acgtctttgg atttcttcaa gtacagacaa agcaataaaa
    12901 gacggatttg caaaattaag aagtggaaaa gaatatgaaa atttgtatta ctcagcaata
    12961 gcacgagcag aagctgattg gattattgga ataaatgcaa ccagagcttt gacaacaaag
    13021 tacaatgcac agctttcttg tggaagagta caaactccta ctcttgcaat gttgcttaaa
    13081 agagaagaag aaataagaaa tttcaaacct aaagagtatt atggattaga attaattgct
    13141 acaaagggaa attcagatat aaaatttatt tggaatgata aaaacaataa ttcttcaact
    13201 tttagtaaag aaaagataga atccacatta aaaaaagtaa aaggtgtaga cataaaaata
    13261 tctgaagtaa acaagtcata taagaaaaaa tattcacctg cactctatga tttaacagaa
    13321 ttacaaagag atgcaaataa aatgtttgga ttttcagcaa aagaaacttt atctataatg
    13381 caaaaactgt atgaacatca taaagtactt acttatccta gaactgattc tagatattta
    13441 acatcagata ttgttggaac attgaaagat agaataaaag ctgtaaatat tagtgattat
    13501 tcaaagattt gtaatagatt attaaaaagc aatattatag ctaataaatc gtttgttgac
    13561 aattcaaagg taacagacca ccatgcaata ataccaacag aacagaaggt attcatgagt
    13621 gattttagtg ataaagagcg aaaaatatat aatcttgtag taaaaagatt tttagcagta
    13681 ctatctcctc cttttgaata tgagcagaca actataagtg caactgtaga aggagaaata
    13741 tttaaggcta agggaaacaa agtaataaat ttaggttgga aagaaagtta taaagatatt
    13801 gaagatgaag atgagtatga aagtatacca aatgttttag aaaaagatgt acttaaggtc
    13861 aagggattaa agataacttc aggaaaaaca aatccaccac catacttaaa tgagggaaca
    13921 ttattgactg ctatggaaaa gaatggtcta gggacagttg ctacaagagc agatataata
    13981 gaaaaattat tcaattcatt tttaatggaa aagaaaaata aagatatata tataacatca
    14041 aaaggaagac aattattaga tttagttcca gtagacttaa agacaccaga acttacagct
    14101 tcatgggaaa agaaattatt ggatatttca aagggaaaac ttagtaaaaa tacattcata
    14161 aatgacatga aagattattc aaaagatatt gtactagaag taaaaaatag tgataataaa
    14221 tttaaacatg ataacttaac taaaaataga tgtccagaat gtggaaaatt tatgttagag
    14281 gtaaatggta aaaaaggtaa gatgttgatt tgtgaagata gagaatgtaa tactagaaaa
    14341 actatatcac aagtaaccaa ttcaagatgt cctaactgtc ataaaaaatt agaacttcgt
    14401 ggagaaggtg aggggagaat cttcacttgt agttgcggat acagagaaaa gttgtcttct
    14461 ttcaacaaga gaaagcaaga agaaaaacag aaggcatcaa aaaaagatgt taatcaatat
    14521 ttaaaaaatc aaaataaaaa tcaagagaca tttaataatc catttgcaga agcgttagct
    14581 aagctaaaaa acaaataatt ttaaagttat tattatacac aattataact ttaactgtat
    14641 attagttata tgtactgata taatatagtg tatagtttag gcatgaaagt agggctgtta
    14701 aatggattta agtggcatat ttaaatacta ttgtaaagag tgtgaaaata catggaataa
    14761 ttcgagtgtt gaattatttg agaatataga aacgtatagt aaagattcac aaaaaaagag
    14821 ggaaaaagaa ttagataaat tgctaaatac aatatcagtt catttagaga ggtatccaag
    14881 tgatgctgta ttgagaaaaa tgtgggtaaa aaagggcgag gttttcttac aaaagacatt
    14941 gggaaaagaa aatattttta agttagaaaa aatggatgta gaggatagaa aaaaattttt
    15001 agatataaca aaacagttta ttagagatgc tagaaaattt gatgatgatt tacctatagg
    15061 tgatattatg caagctatga ggaatgtatg gatttcaaat gcattacaat tattatttgg
    15121 taaagaagta tattattcaa aagctaactt tgcatatagt atgttatatc catatactga
    15181 taattattta gacaatacaa atatagataa aaatgataag attttattta ataactggtt
    15241 agaaaaaagg ctcctgggag aacacattaa atctaaggat tatcatgaaa gtaaagtatc
    15301 tcaaatgata gattatattg aaagtgtata ccctagagaa aagtttacag aagtttatga
    15361 atcgttatta ttaatattta aaagtcaagt aaatagttta aaacaacatg gtaaggaaaa
    15421 tcatttgtgt aaagaagatt tattatccat ttctattgaa aaaggaggtt catccgtttt
    15481 agtagatgga tatttaataa gtggattgat gacaaaggaa gaaatagagt tttgtatagg
    15541 atatggattt ttattacaaa tatctgatga tttacaagat ataaaagaag atttaaaata
    15601 caaccataaa actattatta cagagatgtc aaaagagggt actttagata aagttgtaaa
    15661 taaactaata aattttacta ttgagttaat agatagtttt aaaattaata ataaaaataa
    15721 atctgtaata actatgataa agaatgattg cttaatgtta attttatttt ctgtagttta
    15781 taatgctgaa tttttttctg taggatatat aaaagaagta gagaaattta ttccatatac
    15841 aatagattat tcattagaga ttgaagaaaa aataaaagaa aaatttaaaa atatagatgt
    15901 tttaaataat gaaaatgaat ataaagaaat gattgatatt atttgtgcag agtagaaaaa
    15961 aagggagtgt cttagaatag actttttagt ttatgaggca ctctttttgt ataaaatcaa
    16021 atgtattttc atcattttaa caattaaaaa gagcttatcc ctatttgaga aagccctttt
    16081 taatttaaat aaaaatgtca aggttaaact atttaaatgc agtaataatc ccattatcat
    16141 gtaagttttt tatgattgta gctgcgatag ggaatccaaa taatccagct attccaaata
    16201 gttgagctcc aacaaacata cacattaatg ttattaaagg atataggcca atttggtgtc
    16261 ctactacctt tggttctaat atttgtctaa caacggttat aattatgtat agtattaaaa
    16321 gtcctattgc taaattaata tttccattaa tgagtgagat aatcatccaa ggtgtcaaaa
    16381 tacttcctgt acccaagact ggcaaaatat caacaagtgc tatgatgaca gatatagtaa
    16441 atgcattttc aacctttagg atagtaagtc caataagtag ttctatgaat gtcactgata
    16501 gtagtattgc ataggctttt agtagtttta aaagagcatt aatactgcta ttttttatat
    16561 ttattatcat aaattgactt ttttctggaa attgttttaa gataaagttt actatttttt
    16621 gatagtcaaa agtaaagaaa aaagaagcaa ttaaagtaat aataagtttt aacataaatg
    16681 caggtgtttt acttgcaata ctagcaatag cattgagtgc atttgttgaa atagaagcta
    16741 ctaaagacat catagattga cttatattat cccaaccaag tattaatgct aggttaacat
    16801 taggtgtact agcatctatc tttgaaaata aagtatttag cgttggttgt atacttgatt
    16861 tatatatttc aggaagtcta aaaaatacat cacttacact tgcaaatatc ttcacaccaa
    16921 agctaactaa taaaaatata cacaacccat aaaaaattaa aagtattact atagaaataa
    16981 gtgtacgatt taaatttgta ttatttgtaa taagtcttat aataggtctt aagatggatg
    17041 caatgataaa actgattaca aaaggcatta ataatggcaa taagaatttt aatacaatat
    17101 atacaatact tgttattaaa actacatatg taaatttaat tataaaattc ttttgctttt
    17161 gaatatccat aatataaaac ctccaatgta tttgatatta ttctaaatat ggtctttttt
    17221 acagaaaata tactactgta tattgattat aaactataaa gcttatgtaa agtaaataaa
    17281 ttatgtaaaa tttaggttaa ttttgtataa agagatactt ttatatttta caattaataa
    17341 ccaaatacta aaaaatattt taaataaaga acttaaaatt gtgataaaat taatttatag
    17401 atattaaaaa aagtataata tatggttttt aagaggtgct aagatgaaaa attttagaga
    17461 tttaggtggg aacaaaactg aggatggcag aactgtaaag aagggattat tttataggtc
    17521 tgcaaaatta tcaaatctaa gtgaaaatga tataaagatt ttaaaagagt taaatattaa
    17581 atatatattt gattatagaa gtgatgaaga agctcgtaaa catccatcaa caataatatc
    17641 aaatataaaa aatataagaa taccagcaat gagagagcta gaagaatcag gaggaagttt
    17701 tggttctatt gaagatatga ttgatggatt gtttgaaaaa gatggtgcat ttaatatgtt
    17761 aaataatagt tactataatt tgcctataaa taatccgtca tataaaaaat tagtagaact
    17821 tataagagac tattctaatt taccaatatt aaatcattgt acagctggta aggatagaac
    17881 tggtgtgggg agtgctataa ttcttatgat tttaggggta tcgagagaga atataatgaa
    17941 agattatcta aaaagtaatg attttgcaga taaagagata gaaagattta tagaatataa
    18001 gcctaaattt aaggacattc caaaagaaaa tttgaaatat atatttggtg taaatgaaga
    18061 gtatatgaaa actgcattta gaagaattga tgaagaatac attagtgtag aagcatattt
    18121 atatggagaa tttaatttaa ataaagaaga aataagaaaa ttaagaaatc aatatctaga
    18181 gtaaaaggtg agtttatgag tttaaatata acagcaagac agataaatat aataaaaata
    18241 ttgttaaatt caaaagatac aattagtggt attgccttaa gtcaagagat aggatgttct
    18301 tcaaaaacta tacaaaatga aataaaggat attaataaac aacttagaaa tggtaaaatt
    18361 ttgtcaataa gaggagttgg ttataaacta gaaggaagtt ttgatgaggt aaatataaat
    18421 agcaatctct atgatgatgt agatagagta gaatatataa tcagaaaaat attaacctta
    18481 agtaatgaag aaaaaaatac tataaaactt gaagatttag ccgattctat gtatgtaagt
    18541 gtttcaacag taaaaaatga tttaaaagaa gtaaaaagaa tgttggaaaa gtattcaata
    18601 tcagttaaat ctaagcataa acaaggtata tgtgttttgg aaagtgaaga taagatatta
    18661 aattgtatag ttgacttaag caataagaga gataatcaat tgagtttaaa tgatttttta
    18721 aatgatgata taaaggaaag aaaactatta ataaaaaaat tattattaga catattaaat
    18781 gaaaatggat tagtattaac tgatatagaa tttaagagtg tgttaaataa tatattagtt
    18841 atgttaagca gacataagta taatgaaaaa gaatttatag agaattatat agaaaattat
    18901 aggagcaaaa gaagctcaat tttagaaaat gaacaaaaca aagaaattat aataaattca
    18961 ataaaaacat tttgtaaaaa tttaaaatta gctacatcaa tagatataag taatgataag
    19021 gtatttgaag agtttttata taagcatatt agtagtttat gtaaaaaaat aaagttaggt
    19081 ataaatcaat cacctataat ggctcaagat ataaaaataa aatatccatt tgcttttgaa
    19141 ctagctaata tagctaaaaa gacaatagaa aaagatttga agatagaaat taatgaagat
    19201 gaagttgcaa acatagctct acatatagga ggagcagttg aaagagcatc ttataataat
    19261 aaagataagg ttttcaaaac tataatagtt tgtacttcag gcataggcac atcaatgtta
    19321 ataaaagcta aattagagaa tatatttaag gaaaaattag aaatactaaa gattattcct
    19381 tcatacttag ttgaatatat aaaagttata gatgttgatt ttgtaatatc tactgttcct
    19441 attgaagtag gagatgtgcc agtaataaat atatctccaa ttttaagtga gaaagaaatt
    19501 agattaattg aaaaatatat agaaacagga aatatatacc tagatttaga tataaaaagc
    19561 ctgtttgata gtgaattatt ttttactgat ttggtgttta aaaggaaaga agaagttata
    19621 gattttatgg caagtaaact tgtacaaaag ggctatatag atgaggatat gaaaaaatct
    19681 tactttgaga gagaaaaaat agcaacaaca gaaataggga atatggtaac tataccacat
    19741 ggagctattg gaaaaatttt tgataataaa atagcaattg gtatattaaa gaagcctatt
    19801 tcttgggaaa tatcagatgt tcgtttaata ataatgttag cccttgataa agataaaata
    19861 ttagattatg aagtaatatt ttcaaaaata tataaaagag tagattctat agcaaaagtt
    19921 ataagtatat gtgaaaatag tagttttgaa aaatttgtaa atttatttaa ttagatgggt
    19981 agtattgtat atacacctgt aaatttggat aatataaaac taaataagat aaaaacgata
    20041 aatttctctt ttaattaaga gaaatttttt gactttcaag gatattaata taaagttaag
    20101 atataaacat aaagcaaata aataaaaaag aggtggcaat atgatttata cagtgacatt
    20161 aaatccatca atagattata tagttaagct agatgagcta aagacaggaa gtacaaatcg
    20221 tgtaaaagaa gaatacgttt atccaggagg aaaaggtata aatgtatctc gcatacttaa
    20281 ggaacttgga aatgataata catctttagg ttttataagt ggttttactg gagaatatat
    20341 aataagaaca ttggaagaaa aagaattgaa gacagatttt ataaagataa aaagtggttt
    20401 ttcaagaata aatgtaaaaa taaaggcgtt aaaggaaact gagattaatg gacaaggtcc
    20461 aaatatagat gatgaagaca ttgatacttt atataaaaaa cttgataagc taaatcaaga
    20521 tgatatttta atattggcag gaagtatacc atctacttta gatgaaaaac tatacgaaaa
    20581 tataatggct agattagaaa aaaagaatat aaaagttgta gtagatgcaa ctaaaaatct
    20641 tcttcttaat gttttaaaat ataaaccttt tctaattaag cctaataacg acgaattaga
    20701 agaactattt ggtgttaaat taaattcaat tgaagacatg gtaaaatatg ctaggaggtt
    20761 aaaggaaatg ggagctataa atgtcttggt atcaatggga aaagatggag cattgttgat
    20821 tacagaggaa gatgaagtgc ttataagtga tgttccaaaa ggaaaagtaa aaaattctgt
    20881 aggagcaggt gattcaatgg tagcaggatt tatatctggg tatttgaata ctgggaaata
    20941 tgattatgct cttaaattgg gagcagcttc aggtagtgca actgcttttt catatgactt
    21001 agccaaaaga gaacacattg ataaattggt aaatgagata tctgtaaagc agttttaaaa
    21061 tattaaaaaa tatatagaaa ggtaattaat atttatgaaa attatagatt tattagatga
    21121 aaagtcaatt aagttaaatt taaattcaaa aaccaaatca gaagcaatag aagaattagt
    21181 agatttggtc gcaaatagtg gaaatttaaa tgataaagaa aactacaaaa aagcaatttt
    21241 ggctcgtgaa gaaatgagta caacaggaat tggagaaggt gtagctatac ctcatgctaa
    21301 aaattcttca gttactaaag cttgtatagc agcagcagtg tcaaaagaag gtatagatta
    21361 tgaatcgttt gacggaagtt tatcaaatct attttttatg atagctgcac cagacggagc
    21421 taacaatact catcttgaag tattatcaag attatctaca atacttatgg atgaagactt
    21481 tagaaataaa cttataaatt caagctctga aaaagaattt aaggaaataa tagataaaaa
    21541 ggaaagagaa aaattcagtg aagaatatca agatgagaaa gttgctgaaa aaaatataat
    21601 agatactaaa gagaatgatg ctaataagta tcctaaggtt ttagcagtaa cagcatgtcc
    21661 aactggaata gcacatacat ttatggcagc tgaaagttta aataaaatgg cagaaaacaa
    21721 aggtgtatca ataaaagtag aaactaatgg ttcagcaggc gttaaaaata agcttacaaa
    21781 agatgaaata gaaaatgcaa catgtataat agtggcggca gataaaaatg ttgagatggc
    21841 tagatttaat ggcaaaaaag tcataaaaac taaggtggct gatggtatac acaaagcgga
    21901 agaacttata gacaaggctg taaatggaga tgctccaatt taccatggag gagatggaag
    21961 tcacaacgaa tcaaatgaag aaagtgaaag tggatttaga aaagtataca aacacttaat
    22021 gaatggtgta tctaatatgt taccatttgt tattggtgga gggatactta tagcgatagc
    22081 ctttttactt gatgattata ctattaaccc ttcaaacttt ggttcaaata cacctatagc
    22141 agcatttttt aaaggaatag gagataaagc ttttggattt atgttacctg tacttgctgg
    22201 atatatagca tactctatat ctgatagacc agcgtttgtt gtaggatttg taggaggtgc
    22261 tctagcaggt gatggtggtt caggcttttt aggtgcacta cttgcaggtt ttatagcagg
    22321 ttatttagta gaagggctta agaaaatatt tagtgtacta ccagcttcat tggaaggaat
    22381 aaaaccagta ttgttatatc ctttacttgg aacacttttg atgggaatta taatgacatt
    22441 tttagtaata cctccagtta cagcaattaa taatgcaatg gttggatttt taaatggttt
    22501 aggtggaact tcaaaaatat ttttaggatt agtattaggt ggaatgatgg ctgtggatat
    22561 gggtggacct gtaaataaag cagcatatgt atttggagtt gcatcacttg aatcagggca
    22621 gtttgaaata atggcagcag taatggctgg tggtatggtt ccgccacttg ctatagctct
    22681 tgcaactaca ttttttaaga atagatttac taaagaagaa agagattctg gtaaagttaa
    22741 ttatgtaatg ggattatcat ttgttactga aggagcgata ccttttgcag ctggagaccc
    22801 acttcatgtt ataccagctt gtgttggagg ttcagcagtg gcaggagcac ttagtatgtt
    22861 gttcaacgca gctcttcgtg cacctcatgg aggagtattt gttataccag tggttaccca
    22921 tccatttgca tatatattag ctatagctgt aggtgctttg gttggaatga tgcttttagc
    22981 attacttaaa aaaccattaa atcaagaagt atagcaatta aaggatattc aagaacttaa
    23041 aatatgatgt tttataaaaa ttaatatatt gctgaattat tttaaaataa ggattttatg
    23101 aggctgttat ataacgattt gtaattgtta tcttgacagt cttttatttt tatataagta
    23161 aaataagtgt gttttgcttt atttgtattt aaattgtttt taagttagaa t
//
LOCUS       DAEPXW010000061        22962 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.062, whole genome shotgun sequence.
ACCESSION   DAEPXW010000061 DAEPXW010000000
VERSION     DAEPXW010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22962
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.062"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            35..373
                     /locus_tag="KRM55_002382"
     CDS             35..373
                     /locus_tag="KRM55_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBH1594619.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGKP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(500..1789)
                     /locus_tag="KRM55_002383"
     CDS             complement(500..1789)
                     /locus_tag="KRM55_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1594620.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            1869..2573
                     /locus_tag="KRM55_002384"
     CDS             1869..2573
                     /locus_tag="KRM55_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBH1594621.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHSKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKLNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            2665..3711
                     /gene="selD"
                     /locus_tag="KRM55_002385"
     CDS             2665..3711
                     /gene="selD"
                     /locus_tag="KRM55_002385"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2713..2715,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBH1594622.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            3729..5141
                     /locus_tag="KRM55_002386"
     CDS             3729..5141
                     /locus_tag="KRM55_002386"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBH1594623.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            5255..7138
                     /gene="selB"
                     /locus_tag="KRM55_002387"
     CDS             5255..7138
                     /gene="selB"
                     /locus_tag="KRM55_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBH1594624.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            7243..9981
                     /locus_tag="KRM55_002388"
     CDS             7243..9981
                     /locus_tag="KRM55_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBH1594625.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(10100..11044)
                     /gene="manA"
                     /locus_tag="KRM55_002389"
     CDS             complement(10100..11044)
                     /gene="manA"
                     /locus_tag="KRM55_002389"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBH1594626.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            11217..12578
                     /locus_tag="KRM55_002390"
     CDS             11217..12578
                     /locus_tag="KRM55_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1594627.1"
                     /translation="MELFKAESKKYEKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TLEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            12666..14555
                     /locus_tag="KRM55_002391"
     CDS             12666..14555
                     /locus_tag="KRM55_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1594628.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAIKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKANTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            14570..15025
                     /locus_tag="KRM55_002392"
     CDS             14570..15025
                     /locus_tag="KRM55_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1594629.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            15084..15401
                     /locus_tag="KRM55_002393"
     CDS             15084..15401
                     /locus_tag="KRM55_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH1594630.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            15426..16688
                     /locus_tag="KRM55_002394"
     CDS             15426..16688
                     /locus_tag="KRM55_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH1594631.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            16793..17857
                     /locus_tag="KRM55_002395"
     CDS             16793..17857
                     /locus_tag="KRM55_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1594632.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            17911..19089
                     /locus_tag="KRM55_002396"
     CDS             17911..19089
                     /locus_tag="KRM55_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH1594633.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(19280..20338)
                     /locus_tag="KRM55_002397"
     CDS             complement(19280..20338)
                     /locus_tag="KRM55_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBH1594634.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            20405..20776
                     /locus_tag="KRM55_002398"
     CDS             20405..20776
                     /locus_tag="KRM55_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBH1594635.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            20813..21487
                     /locus_tag="KRM55_002399"
     CDS             20813..21487
                     /locus_tag="KRM55_002399"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBH1594636.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            21736..22575
                     /locus_tag="KRM55_002400"
     CDS             21736..22575
                     /locus_tag="KRM55_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH1594637.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDSNDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            22819..22915
                     /locus_tag="KRM55_002401"
     tRNA            22819..22915
                     /locus_tag="KRM55_002401"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22853..22855,aa:Sec,seq:tca)
BASE COUNT         9164 a         2449 c         3954 g         7395 t
ORIGIN      
        1 gaaaatcaat atcaaataaa tgggaggaaa tctaatgaac ttattagtga ttggtggtca
       61 tgaaagaatg gaaaaagatt atatggttat ggccaagaaa aaaggttata agacaaaggt
      121 atatactacc atgtcatcta aattaaataa ttctatagga aaaccagatg cagttgtcat
      181 acttacatca actgtttcac ataagatgtc tagaacggtt gagtctcaag ctaaaaaaca
      241 agatatatta atcgtaaggc ataaaaatag tagtaaggta gcatttaatg aatgtctaga
      301 tatggttgat gaatgtctgg gaaattgttc aaaatgtaag cttaaagaca aacaaaaaca
      361 aaaaaatata taggtataaa aaatacataa acataaaatt aaaagtactg agataatagt
      421 tataattatt atctcagtac ttttagattt ataaggataa gtatagtata aattttttat
      481 tataatttcc aactacttgt tactttttca tatttttttt acttctagct ttttttcttt
      541 ttttcttctt tatatttgaa gctattataa ataaaactaa aagcactaga atacctgcaa
      601 taatcttaac aaaagtcatt aaaacattat tttcagtcaa aaatggaaga ctgctatcaa
      661 gattattttt tgcaattaag tctatactgt tttctagttt accattatta tatacattta
      721 aagtaccaac cttagctcct ttttttatag gcaaatcaat tttatttaac tctgttttgg
      781 tatcataatt gccttgagat tcatcttttt ctaagaatat cctataacta ttttttggtt
      841 cataaatcaa ttcatgttgt tttgtaaaca atactttttt agtatctgtg tatttttctt
      901 tatcaacaat agtagcacac ttaaagttat caaatccata atcaatcaga atacgtgagt
      961 ctaaatataa atcagcatta gttgaattaa atacagcaac gataactctt ctgccatctt
     1021 ttacagcact cgataaaaga catttaccag cagcatcagt atatccagtt tttataccat
     1081 caactatatc atattttata tttataggtt gacctttgta tgtaatctta tcatgtgatg
     1141 tcaaaaactt attagtgttt acaaagtatc tctcataagg atatgctttt gtagcttcaa
     1201 atttaagtga cttagttttt acaatttgtc taaaagtatc attattcata gcttctctag
     1261 ctatgagagc catatcatga gctgttgtgt agtgatttgg gtctggtaat ccatgaggat
     1321 tattaaaatg agtattagta gctccaattt tttttgcctc agagttcatg aggtcaataa
     1381 atttttgtac attgccacca ccaacatatc tagctaatac aaaagcagca tcattagcag
     1441 aatgaaccaa aagagcatct agtaactgct ttacagtaaa agattcccca ttttttagat
     1501 acatactaga gccatctatt tgaggtaaat ctttaatttc tattacttga tttaaatctt
     1561 taacctcctt tagaactaaa caagctgtcc atactttagt tgttgaagct ggataaagct
     1621 tagaatttcc atccttatta tatagtattt tgccagactc atagtccatt aaaactgcat
     1681 gtttagcaac tatagctggt tcattatctg caaaagagat attagagctt cctaaaaatg
     1741 aagtaaatat caataaacag attaataaaa gtgataaatt tcttttcatt gtgagcctcc
     1801 aaattttaaa ttcatctttt agtatagcat atatttgtca ataattaaaa gaaaggagtg
     1861 attaatatat gaaaaaaaag gtaaaattta tttcgttttt tgttttattt attttaataa
     1921 tatcatcaat aatcgtttat aaatcgctta ttttcaaaga tgatatttat gttgtaagta
     1981 aaaaaaattt acctaatgaa aaaacacatg ttgtagagaa tgaaattaaa ggtgaagata
     2041 ataatcacag taaagtaact aaagacatag ataaaaattt tcaaaataat aaaataacta
     2101 tatacataag tggagcagta aatagacctg gaattgtaac tatagagtca gacaagagac
     2161 tttatgatgc tgtagaatta ctaggaggaa cgacaaaaga agcagattta aatggagtca
     2221 atctatcagt aagattagaa gatgaacaac attacataat acctaaaata ggtgaagcaa
     2281 catctgttac aagtaatgat gattccaata aactaaatca gaagaatgag tcaagaggtg
     2341 agcctaaaaa taaatccaat aaaaatatat ctaacgaatc aaaagtaaat ataaatgtag
     2401 cgacgataga agagttggat tctctacctg gggttggaga agctacagcc aataaaattt
     2461 tacaacacag agaagaaaat ggacagttca gttcaattga ggaaataaaa aatgtaaatg
     2521 gtattggaga taaaaagtat gaaaatataa aagatttaat ttgtgtagac taaaatataa
     2581 tacaaaactt acatatagat atgttattat aaatatgtat gtatatgtgt gtacatgtgg
     2641 aaatttagta aaggaggcac ttttatgaaa aaagaacaaa aaaaacttac agagatgaca
     2701 acagcaggtg gttgagccgc taaaataggg ccagaggttc tggcatcagt tttatctcaa
     2761 ttgcctaaaa atgataatat agaaaattta ttagtaggac tagatacagc agatgatgct
     2821 gcagtttata aattaaatga tgatatggca cttatccaaa ctttagactt ctttacacca
     2881 atggtagatg acccatacgt atttggtcaa attgctgcat caaattcact atcagatgta
     2941 tatgctatgg gaggcaaacc tttggttgct atgaatattg tttgttttcc atcatgccat
     3001 gatatggatg tacttgcaga aatattaaaa ggtgggtttg ataaagtgaa agaaagtgga
     3061 gcacttttgg ttggagggca tactgtagat gacaaagagc ctaaatatgg tctttcagtt
     3121 tctgggattg taagtccaaa taaagtttta tcaaatgcta ctgcaaaacc tggtgataag
     3181 ttaattataa caaaaccaat tggagtgggt gtattaaata cagccatgaa agaaggtatg
     3241 gtagaacaac atatagcaga taaagtaata gaaataatga tacatttaaa taaatatgca
     3301 gcaatgagtt ttgagaaatt tgatgtaaat tcggttacag atataactgg ttttggtcta
     3361 cttggtcata ctttagaaat ggccaaagct tctgaagtaa gtattgaaat tgaatcaaaa
     3421 catgtaccaa ttattgaagg tgcaatagaa atggcacaaa tgggaattat acctgctggt
     3481 atgtataaaa atatgcatta tgtatctaaa gatgtagaag ttgtaggaaa tatagaagtt
     3541 gcagttcaag atattttata cgacccacaa acatcaggag ggttgttaat ttcagtaaaa
     3601 gaagaacttg cagaggaact tgtaaaagat atgaaattaa atggagcaat agaagctaaa
     3661 attataggtt ctgtagttcc aaaaggggaa aaatatatta cagttttata aaatattata
     3721 gagaaagagt gattgttttg agcaaaagag aattgtttgc aatgttgcct tcagttgatg
     3781 aagtattaag tgataataga attgtagaaa taataaatga atatcctaga agtttagttt
     3841 tagaatctgt gagagaagta atagatttaa aaagacaatt tatattaaga ttaaaagaag
     3901 atgcatcaaa ctctgtaaca atagagtttg gtgaaataat agaatctgca atagagagag
     3961 ttaagttaaa ttactcatta tctttaaaaa aagttataaa tgcaactggt acagttattc
     4021 atacaaattt aggaaggtct ttacttagtg aagatataaa agatgaatta tggtgtgctg
     4081 cttcaaggta ttcaaactta gaatacgatt tggataatgg agaaagaggt tcaagatact
     4141 ctcatttaac tagtacaata aaaagactta ctggagcaga agatgtacta gttgtaaata
     4201 ataatgcagc ggcagtactt cttgtactta gcacaatggc taaaggagga gaagcaattg
     4261 tatctcgtgg agaattagtt gaagtaggtg gttcatttag gattccaagt ataatggctc
     4321 ttagtggtgc agaattagtt gaagttggtt caactaataa aactcatttg aaagattaca
     4381 aggaggccat tacagaagat acaaatgtat tgatgaaggt tcatacaagt aattatagaa
     4441 taatgggatt cacagagagt gtttctatag aagaattggt taatttaggt aaaaaatata
     4501 aactacctgt aatagaagac ttaggaagtg gagtttttat agatttatca aaatatggtt
     4561 tatcttatga accaactgta ttggattcta ttcgacaagg tgcagatgta gtaactttta
     4621 gtggagataa gatgcttgga ggtccgcaag caggtattat agttgggaaa aaagagtata
     4681 tagaaaaaat gaagaaaaat caacttacta gagcacttag agttgataag cttacaatat
     4741 gtgctcttga agcaacattg agaatgtatt tagatgagac aaaagctata gaaaatatac
     4801 ctactttaaa aatgttgaca tataaaattg aagaattaga agtaaaagca aataaactat
     4861 ttgaaaaaat aactgcttta aacttaaatg caaacataaa tatagaagat ggattttcac
     4921 aggtgggagg agggtctatg cctcttgaaa ctataagtac aaaggtaata tcaataactc
     4981 ctgaacatat gaatgtttca tctttagaaa aaaaactaag acttagtgaa gcacatataa
     5041 tagccagagt gtatgataat aaatatgtac tagatgtaag aactatattt gatgatgaat
     5101 ttgatgtaat agttgaggaa ttgagaaaag catttaatta aataaatttg agttaataaa
     5161 tattaaattt agaagtataa gtatgaagtt ttgattaaaa aatagctaca cacacttgtg
     5221 actttagtca tagcaggttt agagggggca aaaaatgaaa aatgtagtaa ttggaacagc
     5281 aggtcatatt gaccacggaa aaactactct tataaaagca ttgactggaa gagagactga
     5341 tacgttagat gaagaaaaaa agagaggtat ttcaataaac ttaggattta cttattttga
     5401 tttaccaaac aatagaagag ctggaattgt tgatgtccca ggacacgaaa aatttataaa
     5461 aaacatgtta gctggagcat caggaattga tatagtttta cttgttgtag cagcagatga
     5521 aggggttatg ccacagacag ttgagcattt agatattcta agctttttaa atatcaaaaa
     5581 tggaatagtg gttctaacta agtctgatac tgtagatgat gaatttagag agctagtaaa
     5641 agaagatatt tgtgaaaaaa taaaaggaac ttttcttgaa gatgctgaaa taattgaagt
     5701 tgattctata tctaaaagag gtatagacac tcttattgaa aaaatagata aaatgagtga
     5761 tgatatagaa gataaaaatg aaaactctcc agcaagactt aatatagaca gagtattttc
     5821 aataaaaggg tttggtactg taataacagg cactttaata gaaggaaaga taagtataga
     5881 agatgatttg gttatatatc cacaggtatt aaaaacaaaa ataagaagta tacaagttca
     5941 tggagaaaat aaagatacag cttatgcagg tcaaagaaca gcaatcaata tatcaaatgt
     6001 aaaagtggat gatataaaaa gaggagatgt tttagctgca ccaaactcat tggaggaatc
     6061 aatgatgtta gatgtaaaat tatcattggt aaatcattta gataaaggat taaagcactg
     6121 ggatagatta agattgtatc atggaactag agagatactt tgtagagcag ttccactaga
     6181 taaagaatta attgaaagtg gagaaagtgg ctatgttcag ttgagacttg aagaaagcat
     6241 agtatctaag aaaggtgata cgtttgtagt gagacgttat tctccaatgg aaactatagg
     6301 tggaggtgta ataattgacc catctcctaa aaaacataag aaatttgatg aaaaagttat
     6361 agaagcatta aaaataaaag aaaaaggcga actaaaagat ataatagaag agtacttaaa
     6421 aaggaattta aaaaattatc caaatataaa agaaataatg agctatagtg gtgctcatga
     6481 agaagatgta aaaagagcgc ttgaaacact tatatcagaa gataaagtat ttattatagg
     6541 aaatatgtat atgcatataa atcaatacaa taaattaaaa gaaaatacaa taaagctttt
     6601 aagtgagtac cataagaagt ataggcttag aaaagggata ctaaaagaag aagtaaggtc
     6661 taagatagag agtaatttta agactaggga gatggatatt ttattagaaa aattgtctac
     6721 agaaaatgct ataaaaatag aaaataatat agtatctcta ttagattttg aggttatttt
     6781 aaatgataag caaaaagaaa tagcaaaaaa aatagaaaaa agattaaaat catgtggagt
     6841 ttcttctata ctgacaatag atgaagtttc tgaaggaaat cataactatg ctgaagtatt
     6901 ggagtcaatg ataggtaata aagtagagaa attagatgat ttgtatataa tggacaaaga
     6961 tatttatgaa aatgcaaaga acattttgat aaattatata aaagaaaata aagaaataac
     7021 attaggagaa tacagagatt tgattgattc tagcagaaag aattgcatga ttatattgga
     7081 aaacttcgat agaaacaaaa taactaaaag agtagaaaac aaaagaattt tgttttagca
     7141 gaaaatgtct gtttttgctt taaggtataa agaaggaatt ataatgtcga gtatcgtata
     7201 attaattagt ataaaatatt aattaagagg aagtgtaaag tattgaagaa tataatacct
     7261 gatgtaaaac cagatataaa agaaagagaa gacatgagcc ttttatttat aataatgggc
     7321 tcagtacttt tattatttat tataaaagat atagagaaat atgaaacttt attacatgcc
     7381 atatatacga tatttttagt agctacagga gtaattatat ttaatactac aaaatttaaa
     7441 gtagattcat tttctacatt tttaggatta atttttatag ctactggagt attggagtgt
     7501 atatatttat ttaattcctt ggggattaaa actaagtcta taatggagat taacatcaca
     7561 atatcagcaa taacagattt atttcctata ctgggtgtat acttaagttt taaatttgtt
     7621 aaggataaca aacaaattta ttcaagtgta attttattta tagcaactgc tacattaaca
     7681 ataacatctt tattcataat atcaggaatt tgtgactatc tgggaaatgg taaatcacaa
     7741 tatgctttag gagttataat atctatattc ataataatta tttctatcat tagtggaatt
     7801 gaattaaatt caagttcaaa taaaggtaaa tgggaatatg atgaaaaaaa gatttttaac
     7861 agaataatag taataataat cttatcaaga gttccaaatc tattgcatat agttattgat
     7921 aatagaaatg tagagaggat attatcacaa ataataataa atgtagcctt atattattta
     7981 tataattaca tagtatctaa gaatattaag aaaacagcac tggaattgca tgatacgaat
     8041 gaagaattaa caaaaaaaac ggaaagttta aaagaaaaga ataaaaaatt aatctatgag
     8101 acagaaaaga tagaggaact taagggaata cttatgaaaa gagaatctag gctacaatct
     8161 acattagatg tagcagtaaa tagcatagta gtatttagca aagatggaga aattacatat
     8221 gcaaataaga gctttagaaa tacttttgga gactataaag aacaagataa attgactgat
     8281 aaaataaaaa acttcaatga tttgatagaa agcattcatt atgtgtttgt tcatgagaag
     8341 aatgcagaga aacttattag tacaagcgat aataaagttt atcaagctat atttgcacct
     8401 ttaattattg cttcacaaac agaaggagta ttgtgtgtac tagaagataa gactaagaaa
     8461 aaggagtacg aacgcaaact tattgaagca aataagagaa gtaaagattt tttagaaagt
     8521 attggagatg gcatagtagt gcttgaaggt aataacaaaa tatatgttaa taatgcatgt
     8581 agggaaattt ttaaaaataa tttagagagt attgattttt cattagtatg taaaagtgaa
     8641 gaaagtatag aaaaaagata tgtaatagat ggtgaagtaa agtatgtaga gatgagtttt
     8701 tctcagtata ctaatgctgg tactaataaa actattattg taatacgtga tacaacctct
     8761 cgaaaaatat ctcaaataaa acttgaggaa agtcaatcat catattcaag atttatagat
     8821 atattacctg atggcatatg cttattaaaa gaagatttaa gtataaacta tgcaaataag
     8881 tcgtttttag atatgctagc ttttacaaac atagatgata taaaagattc taatattaaa
     8941 ctattaatga atgcgaatac tgaagaaaaa atgaaattta cggataatat ggctaaagtt
     9001 ttaaatgaaa atagaagtat acttttactg gaatatgaat tgataaatag ttatgatgat
     9061 atagtagaag tagaattaag tgcattacct tttgctatat acaatactag atacataatg
     9121 cttattataa aagatttagt acataagaaa tattccgagc aagcagaaaa agaactgctt
     9181 gaaagattta aaacagataa aatcaaaacg gagttttttg caaatatgtc tcatgaacta
     9241 aaaactccac taaatgttat atctagttca aatcaactgg tagattcttt ctatagaaat
     9301 gaaaagataa aagattacaa taacaatatt aaatctcatg tggatttagt tagacaaagt
     9361 tcttataggc ttcaaagatt aataaataac attatagatt taacaaagat ggagtctggg
     9421 ttctatacac taaaacttgc gaaatacaat attgtatctg taatagaaga cttatttatg
     9481 aatatagaag agtatgcact tagaaaagac ataaaaattc tttttgatac agaccttgaa
     9541 gaaattaatg tttatataga caaggttgaa attgagagaa ttatgttgaa tctattgtca
     9601 aactgtatta agtttactga taatggaggc tggatatatg taagtattca ttataaaata
     9661 gataaagtaa tcataagtgt aaaagacact ggagttggaa taccacaaga taaattagag
     9721 ttgatttttg aagaattttc acaagttgat aagactttat ccagaaatac tgaaggaagt
     9781 ggaatagggc ttgctatagt taagaatcta gtaagtcttc atggtggaga tatagaagta
     9841 gtaagtgaag tgaataaagg cacagagttc ttaatttcac ttccaatgaa gggatttagt
     9901 agtgaacatt acacagaaga taagagaata tataatattc aagaaaaaat aaaaatagaa
     9961 ttttctgata tatattatta aaaatgatta tgagcaaaaa taaaataaaa atactatttg
    10021 tttaaatatt taagttgtaa gaaataggct atcataaggt aaattattat gatagcctat
    10081 ttttagctag gttttatatc tatatgtgag aacatataat ctctaaatta ccttcaaaac
    10141 taaaatctcc aaagtcgttt ggtagtataa aatgcatacc cttttttaaa ttgtattcta
    10201 cagaattgtg tataagtttt ccatttccat ccaacacact gtataaagaa aaaggtgtat
    10261 tgtgtgtaaa attacatttt ccaaaaacat ctaatttata aacactaaaa aattcgtttg
    10321 acacaaatgt tgtgcattta aagtctgatg ttgatacgat tttatagtca gtatcgaaat
    10381 ttatatgagg aacattcgta acatctattg atttttgaac atgaagttca cgcttattac
    10441 ctgaattgtc agttctatca taatcataga ctctataagt agtatctgag ttttgttgag
    10501 tttctaaaat caatgttcct ttgcatatag catgtatagt gccacttgga acatagaaaa
    10561 agtctccctt ttttatatta acctttctaa gtagtttgtc ccattcatta ttatttacca
    10621 tatttacaaa ttctttatga gattttgcat tatgacctat tataatttct gcatcatcag
    10681 aacaatctat tacataccaa cactctgtct tacctaactc tccattttca ttttttttag
    10741 catattcatc atttggatga acttgaactg ataaattatc atttgcatcc aatatttttg
    10801 taagtaaagg aaacttatca ccaggtgtgt ttccaaataa ttctctattt ttattccaca
    10861 attcagatag ttttttacct ttatattttc cattttctat taagcaatct ccatttttat
    10921 gagagcttat agcccaacat tcaccagttg ttggcgaatc tatttcataa ttaaatttat
    10981 ctttaagtgc agtaccaccc catattctat ccataaaaat aggttttaaa aataatggtt
    11041 ccataatcct gttcctccta tgatattaaa tttatcctac aaataattat atataaatag
    11101 attataaaat caatagtaaa aaagttttgt cccttgaaat gacataaagt ataaggagtt
    11161 attaaataag ataaactatg atatataata taaagttcta aattggagtg ataattatgg
    11221 agttgtttaa ggcagaaagc aaaaaatatg aaaaagaatt tttaaaatta ttggagcaat
    11281 gggttagtat accttcattt tatgatagaa aaactgtatc taaagatatg ccttttggaa
    11341 aaggagtata tgatgcatta aactggtttg aaaatctagg tagagaaaac aatttcaaag
    11401 taaaaaatat agataatcat gctgttcaaa ttgaatatgg aaatggtaaa gagtatgtag
    11461 atatatttgg acattgtgat gttgtaaatc caggtgaagg atgggatagt gaaccattta
    11521 aactaaatat tataggtgat aaattagttg ctagaggtgt atctgataat aaagggccta
    11581 tgatagtgaa ttttttagca ctaaaaatga taaaggattt agatattaat ttaaagagaa
    11641 aggttagatt aatagctggg ggaaatgaag agagtggatt taaatgtata aagcattatt
    11701 atagcaaaga gccatatggt gtatgtggat ttactccaga tgctaaattt cctgtattaa
    11761 atggagaaaa aggtggagca ataataaagt taatttcaaa tatagacgat aaatctttat
    11821 atataagtgg tggaatagag tttaatacaa taccagataa agtttatata aagaatgtag
    11881 aaaaattggg taaagataat atatgttttg atattaacaa tatatcgata aattatgata
    11941 atggcaatta tattgtgtat ggaaaaggtg gtcattcatc taaacccgaa aaatcaataa
    12001 atcctatatt agctacaatt aaacttttgt cagaaaatat tgatgaaaaa tggacaaaag
    12061 atttatataa gttgataaat caagataata taaatggaaa cttatttggt ttaaatattg
    12121 aggggaaatg tgggatttta tcaatggtgc caacaataat aaatatagta gatggaaaat
    12181 tagaagtagt tttaagcgtt agatatccag aaatattaac ccttgaagat ataataaaaa
    12241 aatttaattt gtatatggag caaaataata ttaataaatt tgagcttatt ggggaaaatt
    12301 taaagcaagc aaattatata gatagaaatt caaaacttgt aagaagtttg catgatatat
    12361 atataaagta ttctggagat ttaaaaaatg atgttagagt aactagtgca ggaagttatg
    12421 cttctgaaat gaataattca gtaatatttg gttgtgaatt tcctgatggt agctttggca
    12481 atgtccatag tgcgaatgaa tttgctagct tagatagatt tataactgca ataggtatat
    12541 atgcagaggc aataattaca ttatgtaata aaatataaat acaaaatgtc ccttatatag
    12601 acatattata tatacaatta aaattttact tgatatataa ttgaaatcaa agagaaggtg
    12661 atacaatgat aactaagaaa catgcaataa tagtaaagag tttaagcaat aaagatggat
    12721 atatgacatc aaacgaatta gctatcaaat tggatgtgtc tactaaaact attaaaagat
    12781 atatagcaga tttaaatagt gttttaagca agtatgattt ggtaatagct tcttctagag
    12841 gtataggata caagttaagc ggttctaaaa acaatatagc cagagctatt aaagaagcaa
    12901 ataaatatat tgatggtttt ttagatgact ctgaagagtc aagaatgtca aatataatat
    12961 gtatgcttat taatagaaat tatatgagta tagaagcaat ggcagaagaa ttaaatctaa
    13021 gtatagccgc tataaataaa ttgtctagta agcttaaaag aaaacttgaa aagtatgact
    13081 tagttataaa atctaaacct tactatggaa gctatataca tggtgaagaa attaatataa
    13141 ggcaattaat tactgactat gcaataaaat tagatgaaaa aagtaaagtg aaggtgtttt
    13201 tagatgacat tagtgaaaac gatatacact gtatagaaag tattttagaa aagcacttaa
    13261 gagaaaaaga tacaataatt tcagataaag attttaatct tttgctttca aaaataatcg
    13321 tttctgtatt taggagtaag agaggtcata gtaacaatat aaacttaatg gatacaagtt
    13381 atagatttca taactactac tttatagaaa atctaatgaa agaaatatct gataaaattg
    13441 gatttaaact tattgaagat gaagtaattt atatttcaaa ttattctggt gtaatagcct
    13501 ataaaggtac acaaggaaga aaaaacacaa gtgaaattga ggaacgaata agtagtgtta
    13561 taagtagtgc acttcaagat atattcctta tttcaggtag tgattataca aaagatgatg
    13621 agtttatggt tgcaatctct gaccatataa agagattttt aaatagagct agagctaatg
    13681 taaaatcaaa taatccttta cttcatcaaa taaaagagaa gtttcctata gcttttaatt
    13741 tagccgtgtt tttatcaaat aaactagaaa ctgagtttaa tttaaaactt gatgaagatg
    13801 agcttggata tatagctatc cactttgctg cttcaaatga aagaatgaaa aaaaatacta
    13861 gtaagaaaat ttgtatagtt tgtcattatg ggataggaac aggacaactt atttctgaaa
    13921 agctaaaaca gaatataagt gatttaagtg ttgtaggtgt ttatccagtt agatatctcg
    13981 atatggctat aagtcaagat gttgatttga tagtatctac cgttgaatta aaaggatatg
    14041 aaaaacctgt cttatatata gaaaatatat ttgatgatag cttaattgaa aacgtaaaca
    14101 aagcctttta tgaaaaggaa gaaagaagaa agataataag caacatgttt gatgaaaaag
    14161 cttttttcag tataaaggct aatactaaag aagaggtcat aatttcactt tcaaataaac
    14221 taaaagaaag agattttata gaggaaagtt ctataaaaag tataatagat agagaaaata
    14281 tttcatcaac tgaaatagga aatctagtag caatacccca cacaatagtg aagggagata
    14341 aaaaatctat aataggagtt ggaatacttg aaaatccaat aatttgggat aagcaagagg
    14401 ttcagctagt atttatggta ttttttaata ctaaagaaaa acataatttc tcgatattta
    14461 aataccttta taattttata aaagatgaag gcggagtaag aggaattatt aaaatatgtg
    14521 actttaataa attaatggca ctgataggta attaaggagg aaattaataa tgggaacaaa
    14581 catatttaac aaagaatatg tatttttaaa tgttgatgct aagtcaaagg ttgaagtttt
    14641 aaaatttata tcaaaaaaag ctaaagactt aaacttggca gaagatgaga gcttagtata
    14701 tgaaggttta atggctagag aagaacaatt tactacaaat ttaggagaat ctatagcaat
    14761 acctcacact aaaaatgatg caattgaaaa tccagcagta gtagtattga agtttaatga
    14821 agatgttgtt tggaatgaag gtgaggataa ggttaaatta gcaataagct tacttatgcc
    14881 aggaaaaagt aaagagaata ttcatcttaa attattatca tctctttcaa gaaaattaat
    14941 aaataaagaa tttaaagatt ctcttttaaa aagtgataat gttgaagaaa tatctaactt
    15001 aataaatgaa gctttaggtt tataattaaa cactaaggtt ataaaataaa aaaataatta
    15061 actaaaaata ggaggaattt gaaatgaata aaaaattagt agcattatgt gcttgtccaa
    15121 tgggactagc tcacactttc atggcagcag aagcaataga gcaagcagca aaggcattag
    15181 gttatgaagc aaaagttgaa actcaaggtg ctgatggtgt acaaaatgag ttaacaagag
    15241 atgatatatt aggagcaact atgataatac atgcagtagc aataacacca gaaggtatgg
    15301 aaagatttga tggttgtgaa gtttatgaag ttgaattaca agaagctata aaaaatgcag
    15361 aaggtgttat aaaagaaata gaagaagatt taggaatata ataaatttat tgtggaggaa
    15421 atagaatggc aattaagaaa aaagttataa acagttcagg tgcttctaca acaggaggaa
    15481 ataatgtagg aaaatctact ccatctagtc caactcaatc aaagggaaat ggaaaatgga
    15541 aagaaataag taaacatata atgacaggta tatcatatat gataccagtt ttagtaatgg
    15601 gtggacttat aggggcctta tctcaattaa taccatatgc tatattagga cttgacccat
    15661 ctgtaggtat agttgatgct atgaactcag gagaatttac agggttcaag cttagtcttt
    15721 taaatatagc acaattaatg tcaaatttcg gatttacttt gtttggattt gcgataccac
    15781 tgtttgcagc attttgtgca aactctatag gtggaaaaac agctttaatt gcaggattta
    15841 taggtggata tatagctaat aaacctgtag gtgtaccaca attcgttgat ggacaatgga
    15901 ctgaagttgt tccagttgca tcaggatttt taggtgcaat actaatagca ttcataatag
    15961 gatattttgt aaaatggtta aataaatcta taaaagtttc tcataactgg ttagctttta
    16021 aaacaacatt tttaatacca ttaatagcgt cattagcttg tatggtattg atgatattta
    16081 taataactcc atttggtgga ttaattaatg aaagtatgaa aaacttctta acagcagcag
    16141 gagcagctgg agaatatgta tatgcaacag ctttggcagc agctacagca ttcgacttag
    16201 gaggaccaat aaataaagca gcaggattcg ttgcacttgg tttaactaca gagaatgtac
    16261 ttccaataac agcaagaaca atagctatag ttgttcctcc aattggatta ggattaacaa
    16321 cattattaga taaaagatta gtaggaagaa gagtatatga tagacaattc tatcaagcag
    16381 gaaaaacttc tatattctta tcatttatgg gtatatctga aggagcaata ccatttgcac
    16441 ttgagagacc aggttttgtt atacctttaa acatagttgg aagtgtaata ggagctatta
    16501 caggtataat tctaggagca attcaatggt tcccagagtc agctatatgg gcatggcctc
    16561 tagtagataa cttatttgga tatataatag gtatagcagt tggtgctata ttcatagcag
    16621 taggaaatat attctataga aataaattaa taaaagatgg taaacttgtt gtagattata
    16681 tcgactagta tttaattttt actatctata aataactttg gctggtaata tggttttaat
    16741 caatattacc agccttacct atatgattaa ttaaaggcgg tggagataag atatggataa
    16801 gatagaaaaa gtaagagagt attttagaga atatgatata gatggatttc ttataaatag
    16861 tcctacaaac aagttttatg ttggaaattt atttagctct tcaggttatg tttttataac
    16921 taaagaatca caatatataa tagtagattt tagatatttt gaagaaatta aaagaaaatc
    16981 tagtttgttt aatgtagtat taatggacaa aactagaact cattttgata taattaatga
    17041 tatttgtaga gagcagaata taaaggaaat tggatttgag ggaaatgaag tatcttttga
    17101 tttatataga agtatgagta ataagttaag tgcaacctta aaatcagttg atttatctac
    17161 attaagggaa acaaaaaatg aagacgaaat aaaatatata aaaaaagctt gtgaaatagt
    17221 tgatgctaca ttttatcata tagtagactt tataaaggtt ggtatgactg aaaagcaagt
    17281 tgaaaatgaa attgttagaa ttataaaaga tttaggtggt caaaaagaat ctttcgatac
    17341 aatagttgca tctgggctta gaggagcatt acctcatgga aaagcaagtg aaaaagttat
    17401 agagtatgga gattttgtta cctttgactt tggtgctaag tataataatt attgttcaga
    17461 tattaccaga accatttgta tgggtactat aaataaagag ttagaagaaa tatataatat
    17521 agtaagaaaa gctaatgaag agtgtataag ggttttaaga ccgggaatga ctactggaga
    17581 gatagataaa gttgcaagag acataattgg ttcatatgga tatgccaata attttggtca
    17641 taatctgggt catggtgtag gaattatggt tcatgaatat cctgcattag ctcctgaatc
    17701 aaatgaagta ttaaaagaag gaatgattgt aactatagag cctggtatat atgttccaag
    17761 tcttggaggc gtaagaatag aagatgatgt acttataaca caagatggat gtatgagatt
    17821 gactacatct actaaggatt taatagttgt aagctaaaaa taaattagat aaatatttta
    17881 taacaataag aaaagaagag gtaaatttaa atgtataatt ttgatgataa accagataga
    17941 gtaagtgaaa agtgtagaaa atgggattta aatattataa gagataaatt tggagatatt
    18001 agagaagatt ttataccaat gtggattgct gatatggatt ttaaaatacc aacagaaata
    18061 gaaaacaaat ttattgaagc tgtaagaaga ggtgtatttg gatatacata ctgttatgat
    18121 gaattttatg attcagttat tggttggcaa aaaaatatgc atgaggtaaa tgtagaaaaa
    18181 gaatggatta cattaactta tggaactgta tcaacacttc attatgtagt acaagctttt
    18241 tgtaagaaag gtgatagtat aatattaaat acaccagttt atgacccctt tgaatcatca
    18301 gcaaaaaaac aaggtgtaaa tgtaatttgt aatacattag atgttgtaaa tgatagatat
    18361 tatataaatt ttgataaatt agaagttcaa attaaagaaa ataagcctaa attaatgatg
    18421 ttttgtacac cacataatcc atctggaagg atatggacaa ttgaagaaat gacaagggta
    18481 gcaactatat gtaaagaaaa taatgttatt ttggttgcag atgaagtaca tgcagagcat
    18541 attcattatg gtacatttaa ttcaatactt aagattggaa aagagctttt agaaaatgtt
    18601 attctattga catcaccaaa taaaggattt aatcttggtg gattaaagac ttcttattca
    18661 atagttataa ataaggatat aagggacaaa tttagaaata aattaaagca aaattctata
    18721 acttctccaa atgtgtttgg aataatagga ttgataaccg cttataatga atgtcatgag
    18781 tggttaagtg gtgtaaatga atatataaaa tcaaattatg aacttttaga aacttgggta
    18841 aataaatata ataagataaa attgatgaaa atggaatcat cttacttagc ttggatggat
    18901 ataagtggat taggtattag tgcaagtgag tttacagata aattggctat agatacagga
    18961 gtattattag aagatggaag tcattttgta aaagatggtg agaagtatgt tagaataaat
    19021 ttaggaactc aaaaggaaaa tgtaattgaa gccttaaata gaatggattt atttttaaag
    19081 tctttataaa aatttggttg aattagtatt ttatataaat ttaaactatt aatatggtat
    19141 atacataagt agaatttgtt ttagattact taagtatata ccatatttta tataaaaatt
    19201 aaatttgcat tagtcatgtg ataactattt aaattcatat gtattttgta tgtataatag
    19261 atataattat tatttaaact tattgtttat ttaatttttc aatagaaaaa gatttatctg
    19321 taagtttaaa attatctttt atacccttag ttaagtatac tttcttatcc ttagttatga
    19381 atatagcatc tacattatca attttattaa ttaaattcat acctttttca agaccaagac
    19441 caaatgtaga agtggataag gcatcacaat taatagattt atcagagatt attgtaacac
    19501 tacttaaatt gttttcaaaa ggataccctg taaatggatt taacatatga tgatatattt
    19561 ttccgtcttt ttcgataaat ctttcataaa ttccagaagt aacaacagac ttatttgtag
    19621 tttctatgtt tcctatggat tcaccatttt tactagttgg gtcttgaata cctattttaa
    19681 aaggtttatc atttttacca ttttctaaag taaatatatt tcctcctaag tttactaaac
    19741 ctttttttac atcctctgat tttaaatagg ctacaatttt atcagcagca tatcctttag
    19801 ctatggcacc taaatcaatt ttcatatttt ctttggttaa ttttatagat ttattttttt
    19861 catccaatat gatgttctta taatcaataa gaggcagaag tttttgtatc tcagaatcac
    19921 ttggaacttt agctttatct gttccaatag cccataaatt tgataatgga ccaattgtta
    19981 tgtcaaaata tccatctgat aatttggaat attgtatagc ttcttttacg acgaaaaatg
    20041 tatcatcaga aactctgaca aattttttac cagcattatc atttatttta gaaacatcac
    20101 ttcctggtat atgagtgctc attttgttgt caatatatct taaaattgaa tcacattcat
    20161 ttaagatttt atcacttttg gattctttta cattaaatac agtaacttcg tttactgtac
    20221 caaggtagta gctagtttta ctatatttag tattctggct tgaactccta aaaaatgaaa
    20281 ataaaattaa tgctaaaatc aatatcacaa aaataaatgt gatttttttc ttattcatgg
    20341 tatattcctc ctatgaaatt gtgttattat tttattataa cataatttca taggaggaca
    20401 aaaaatgaag aaaaaagaca ttcttcttat tttaggcatt ttggttgtta ttacagcatg
    20461 ttatgggata ataaatgtta taaattctaa aaatgctgga aatattgaga tttatgtaga
    20521 taataaattg tataaaactg tttcaataaa tgccaaagaa gaatttaaaa tagagaatag
    20581 aggggggtat aacatagtaa agattcatga taaaggggtt gagatagtag atgcttcatg
    20641 tcctgataag gtttgcgtac atactggatt tataaacaag ccaagtcaaa gcatagtttg
    20701 tatacctaat agagtgagca taaaaataaa tacaaatgaa aagaatgata atcaagaaga
    20761 tataatttct aaataaaata ataaaaataa ttgaaaggaa ttggtgataa ttatggttaa
    20821 cttaggaaac gattgggatg aattattgaa agaagaattt gaaaaagatt actacttaaa
    20881 cttaagaaaa tttcttatag aagaatataa aacacgccaa attttcccaa atatgcacaa
    20941 tatatatgaa gctttaaaac acacttcata caaagacaca aaagtcttaa tattaggaca
    21001 agacccttat catggagata atcaagctca tggtttagct ttttcagttc aaccacaagt
    21061 gaaaactcca ccatctttat taaatatgta taaagaatta aaagatgatt taggttgttt
    21121 tatacctaat aatggatatt taatgccttg ggcagaccaa ggagtgttac ttttaaatac
    21181 tgctcttact gttagagcgc atgaagctaa ttctcataag aacaaaggat gggaaatttt
    21241 cactgataga gtaatatcta ttttaagtga gcgtgaagac ccagttattt ttgtactatg
    21301 gggaagtaat gcacgtaaaa aagtagagtt gattgataca agtaaacatt atattttgga
    21361 agcacctcat ccaagcccat tgtcagcaag taaaggcttt tttggatgta aacacttctc
    21421 taagataaat gaaattttga aaaagctagg aaaagaacct attaattggc agatagaaaa
    21481 tatataaaag taaaaggtaa caaaatgata acaaaacaac aataaacaat gacattgttg
    21541 taactaatag aaatatgctt aaatagttga aaatactatg tatgcatatt tctatttttt
    21601 tgtcaagttg acaactcttg aaaaaatagt tacaatttag ttacacaaaa aacacaaata
    21661 aaaaaagaaa cttacaaagc agaattttat gaagcaaaat atatagtgta aaaaatctta
    21721 gggaggaaat tttatatgaa ttttaaaaaa ttgagtaatg ctaaagtctc ggtaatggca
    21781 gttgttttat cagttggaat attatcggga tactctgcgc ttaataaaca agtaacatta
    21841 gtagtaaggg gagaagaaag aactatatca acatttagtt ctaatgtagg agacctttta
    21901 gaatctcaaa acattagcta tgattcaaat gatatagtaa ctttagatga aaatacaaag
    21961 ttatctaatg gagataaaat agaagtaatt gatgtaaagg aaaaaacagt tgtagaaact
    22021 aaagacattc catttgaagt tacagttgtt gaagatggct ctttattaaa gggtgattct
    22081 aaggttaaag aagaaggaaa gtctggtaaa agtgaattaa tatataaaga aacttatcac
    22141 aatggaaaga aagtagaaaa ggaatttgtg aaaaaggttg ttaaagctga gccagtaaat
    22201 aaggttgtaa gcaaagggac aaaggtagaa atgcaagtag cctcatcaag gggagaaagt
    22261 tcaagaagaa tggcttcatc atcatctagt agcagtagta gtaacaatgg taaaaatatg
    22321 agagtggtag caactgcata tactggtcac agtataactg caacaggaac aaaacctaag
    22381 tggggaacaa tagctgtaga ccctaaggtt ataccatatg gaactaaagt ttatatacct
    22441 caatttgaca tggtgtttac tgcagaagac tgtggtggag caataaaagg aaataaaatt
    22501 gatatctaca tgaatgattc aaaaacagtt tataactggg gaagaaaaac tatagatata
    22561 cgtatattaa aatagttaaa taatttatat ttttactgga aattatattt tgattatata
    22621 gagaagaaac tctttataga ttctaaaaat ataatttcca gttttttatt ttggatatgt
    22681 aataaaacag gtaaatttta accatgtata gataaaagct atttaaatta taatttacta
    22741 tcatataaat ctataaaaat tgttgcaaag agtcaaaata tatgatatta tagatttcgt
    22801 tgagaaggat ttcattatgg gagtggatgg gtgccggtgt gccctctagt cttcaaaact
    22861 agtatgaggg gttaagagcc tcttaggtgg gttcgattcc cacgcattcc cgccaatatg
    22921 taaaaggtat cttttaatta aaagatacct ttttaaattt at
//
LOCUS       DAEPXW010000062        22879 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.063, whole genome shotgun sequence.
ACCESSION   DAEPXW010000062 DAEPXW010000000
VERSION     DAEPXW010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22879
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.063"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            373..1650
                     /gene="hflX"
                     /locus_tag="KRM55_002402"
     CDS             373..1650
                     /gene="hflX"
                     /locus_tag="KRM55_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH1594638.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNIEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            1883..2380
                     /locus_tag="KRM55_002403"
     CDS             1883..2380
                     /locus_tag="KRM55_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1594639.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIEIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            2430..2954
                     /locus_tag="KRM55_002404"
     CDS             2430..2954
                     /locus_tag="KRM55_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH1594640.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            3266..4630
                     /locus_tag="KRM55_002405"
     CDS             3266..4630
                     /locus_tag="KRM55_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBH1594641.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQKHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            4769..5935
                     /locus_tag="KRM55_002406"
     CDS             4769..5935
                     /locus_tag="KRM55_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1594642.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            6052..6834
                     /locus_tag="KRM55_002407"
     CDS             6052..6834
                     /locus_tag="KRM55_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBH1594643.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDAKNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(6953..7606)
                     /locus_tag="KRM55_002408"
     CDS             complement(6953..7606)
                     /locus_tag="KRM55_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1594644.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(7630..8994)
                     /locus_tag="KRM55_002409"
     CDS             complement(7630..8994)
                     /locus_tag="KRM55_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH1594645.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            9652..11082
                     /locus_tag="KRM55_002410"
     CDS             9652..11082
                     /locus_tag="KRM55_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1594646.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            11185..12288
                     /locus_tag="KRM55_002411"
     CDS             11185..12288
                     /locus_tag="KRM55_002411"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH1594647.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENRKFVAVLKEILNIKGEPSIG"
     gene            12303..12539
                     /locus_tag="KRM55_002412"
     CDS             12303..12539
                     /locus_tag="KRM55_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1594648.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            12556..13605
                     /gene="vorB"
                     /locus_tag="KRM55_002413"
     CDS             12556..13605
                     /gene="vorB"
                     /locus_tag="KRM55_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH1594649.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            13607..14347
                     /locus_tag="KRM55_002414"
     CDS             13607..14347
                     /locus_tag="KRM55_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH1594650.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            14350..14889
                     /locus_tag="KRM55_002415"
     CDS             14350..14889
                     /locus_tag="KRM55_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH1594651.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            15013..17112
                     /locus_tag="KRM55_002416"
     CDS             15013..17112
                     /locus_tag="KRM55_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBH1594652.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNIVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(17379..17894)
                     /locus_tag="KRM55_002417"
     CDS             complement(17379..17894)
                     /locus_tag="KRM55_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBH1594653.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(17986..19197)
                     /locus_tag="KRM55_002418"
     CDS             complement(17986..19197)
                     /locus_tag="KRM55_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH1594654.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            19873..21315
                     /locus_tag="KRM55_002419"
     CDS             19873..21315
                     /locus_tag="KRM55_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH1594655.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            21357..21710
                     /locus_tag="KRM55_002420"
     CDS             21357..21710
                     /locus_tag="KRM55_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594656.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPVSFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            21901..22722
                     /locus_tag="KRM55_002421"
     CDS             21901..22722
                     /locus_tag="KRM55_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH1594657.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
BASE COUNT         8810 a         2612 c         3910 g         7547 t
ORIGIN      
        1 caaataacta cttaaattta agaatagggt taaatataaa atgataatta catataagtt
       61 aattaaacta atgtattttt aatatatatt tagaatttta atccttctta tgatataagt
      121 agcttgtttt gtattactta gatttgtaag gagttttttt attgaaaaaa ctgcataata
      181 tatttgggag gatgtgtaag aaagtgattt tttatataag attgagaaaa taatgcacga
      241 ttatggttat tataatagta aataagaagt gtcatttaag gataagataa aaagcaaaat
      301 tcttgatgaa tttaattata gagccataat ctcgtgctat agattaaata aaaaatagca
      361 gataaggaga atatggatat ggcgaaaaaa ggaataacag taggattaaa cataaataat
      421 aaatctgagg actttaatga actaatgatt gaacttgaaa acttatgttc agcatgtgat
      481 attgatgttg tagggagtat aactcaaaat gcaaagcagg ttaatagagc attttacatt
      541 gggacaggta aagttgagga aatattaaac ttaataaaga aagaaaatat agagatagtt
      601 atattttaca atgaactttc tacatcacaa ctaaaaaata ttgaagaaaa gcttaattgt
      661 gaaattatag atagaacggc attgatactt gatatatttg cacaaagggc aaaaactaga
      721 gaagctaaac ttcaagtaga agtagcaagt ttaaaatata tgttaccaag acttataggt
      781 tcaaatgaaa atttaggacg tcaaagtggt ggagttggta ctaaaaatag aggttctggt
      841 gagaaaaaat tagaacttga ccgtagaaga atagaagaaa agataacatc tttaaatagg
      901 gagttggatg atttaaaatt ccaaagagaa actcaaagaa gtatgagaag aaaatcaaat
      961 cttccaaatg tagctctagt cgggtataca aatgctggta aatcttcaat aatgaataaa
     1021 ctagtagata tatttaaaaa ctctgaagaa aagaaagtgt ttgagaaaaa catgttattt
     1081 gctacacttg aaacttctgt cagaaatata gttcttgcaa ataacaaaga atttttatta
     1141 tctgatactg ttggttttgt aagtaatcta ccacatgact tagtaaaagc atttaggtca
     1201 acattagaag aagcatgtga ggcagacgta ctgttacatg ttattgatat ttcaaatcca
     1261 agctataaaa gtcatattaa agtgacagaa gatactttaa aacaaatagg tgcagatggt
     1321 atacctatga tacatgtgta taataaaatt gatttaatag atgtagaagt attggataga
     1381 attttagata gtatcgataa agaaggtata tttgtttcag ttaaaaaaga tataaatata
     1441 gataaaatga taaaatgtat ttgtgatagc atatttaaag attatgtaag atgtaagttc
     1501 ttaattccat atgataaagg tcatgtagtt tcttatttta acgaaaatac gagcattata
     1561 aatacagaat acagagaaga tggagctatt ttagatgtag aatgtagcaa tatagaatat
     1621 aataagtata aaaagtatgc tttagagtaa attttgaaaa acttattata gcctaaaata
     1681 tatttaattt ataatttatt ataaattgat tgtaaatatg attttatgaa acggtatagc
     1741 cataatgcta tgccgttttg ccatttataa taaaaataaa tttattgaca caatagtaac
     1801 taattactat aatataaagt aactaattac tatttaaaat tatcaaaaaa ttaaaatcta
     1861 agataaagag aagtgtataa taatggatgc agaaagttta atgaaaaaat atatggtaga
     1921 tgatgatagt agaaaacaag ctatatttgc aagtatattt gtaatgcaaa ataaacttca
     1981 aactacatgt gataaattag acccagaatt aacaatgaaa caatggttac ttttagctat
     2041 tgcggactct gtagatgaaa ctcttacatt aaccaaactt ggagaattaa tggggtgttc
     2101 aagacaaaat gtaaaaaaac tagctattgc tttagaaaag aaaggtttta tagaaattga
     2161 gcaaaatgaa aaagattcaa gagctatctg tcttgtgaca aaagatagag tgcaagagta
     2221 ttctaaaaaa gtaagaggta tgcaggaaaa agtattacag cttttatttg aagattttac
     2281 agagaaagaa gtggaacagt tattttttgg aattatgaaa ttaagtatag gaattgaaaa
     2341 tgtgaaaaat tatgtagaaa ataatgacgt tggagaataa gcaagtatca aatcaacttt
     2401 gtatgacatc agagaggggg gtaatttata tgaaaaatgt agtagtgatt tataagagta
     2461 agtatggttc aacaaaaaaa tatgctaaat ggctttcaga attattgtct tgtgatattt
     2521 ttgaaactaa gaatattaat atagaaaagg ttatgaagta tgatacgatt attttaggag
     2581 gaggtcttta tgcttgtaat atagcgggaa tttctttctt aaaaaaaaat tataaagaat
     2641 tgcagaaaaa aaatttagta gtatttggcg taggagctgc tccatatgat gatgaagtaa
     2701 taaagaaatt aagagaagta aattttaagg atgaattaaa caaaattcct tgcttttatt
     2761 gtcgtggggc atgggatgag acaaaaatgt cttttataga ttatactctt tgtagttttt
     2821 ttaaaaaatc tatagctaaa aaagaacgtc aaggtcttaa accagcagaa gcacctttat
     2881 tgtctggaga agcatttgat tggtgtaata aagaaaattt aactccaata cttgattata
     2941 taagagaact ttaagaggta tatatttata attatttatt atctaaagtt agatttcata
     3001 gaaacttact agacattatt tataaaataa tattattaaa gatggataat ttaatttttt
     3061 caataaggtt ataattttaa aaaatgttta ttttaaaata aattatttta taagcttact
     3121 tatacttaat aaggggcttt ttttattgga agatttatgt tatattgaga tgaatttatt
     3181 atgatataaa aaataatgtt aggataaatt taaatctttt tctaaaaatg tattagtata
     3241 attcttaaag aaaggatttt taacaatgga tataaaagag ttggttaaaa tgcaaagaaa
     3301 atattataat acaggtaaaa caagagatat atcgtttcgt atagaacagt tgaagaaact
     3361 taagttagtt gtatcacaaa atgaagaaaa aatactttta gcactaaaga aagatttaaa
     3421 taaatcggat tttgaaggtt ttatgacaga ggtaggcatg ttttatagtg aattaaactt
     3481 tgctataaag aatataagaa aatggagcaa aataaaaaga gttaaatcaa gtatggttaa
     3541 ttttccatct atatccaaag ttgttccaca accttatggt gttactctca taatgtcacc
     3601 ttggaattat ccatttcaat tagcacttat accattagtt tggtcattag cagcagggaa
     3661 ttgtgttata ttaaaacctt ctgaatattc tgtgtcaaca tctagtgtag ttaaagacat
     3721 agttgaagat actttttcaa aagaatatgt tgcagttgtt caaggaagtc aagaagaaag
     3781 tgaaaagtta ctattggaaa gatttgatta tatatttttt acaggaagta ctaatgttgg
     3841 taaaataatc atgaaatcag catcagagca tttaactcct attactttag aacttggagg
     3901 aaaaagtcct tgtatcattt taaaagatgc taatatagac cttactgcca aaagacttac
     3961 ttggggaaaa ctaataaatg caggacaaac ctgcgtggct ccagattatg ttttagtgca
     4021 tgaagataga aaaaatgagt taatagagaa aataaaatat tatactaata agtattttgg
     4081 agataatcca tgtaataatg agcaatttcc taaaatcata aatcagaaac attttaatcg
     4141 gatattatct cttattgata aagataagat agtctatggt ggaaattata ataaggagac
     4201 attaaagata gagccaacta tagtagacaa tgttaattgg gatgataata taatgaagga
     4261 agaaatattt gggcctatat ttcccatttt aacatataaa gatttggatg aagtaataca
     4321 aaaaattata caaatgccaa atccattggc actttatatt tttacaaaaa ataagtacct
     4381 agaaaataaa cttttagaaa tgattccagc aggaggatgt tgtatcaatg atacagttac
     4441 tcatatagct acaaattact taccttttgg tggtattggt gaaagtggta tgggctcata
     4501 tcatggaaaa gctggattcg atacatttac tcattataag agtgtgttaa aaaaattaaa
     4561 tttggatgtc cctattagat atgctccata cgataataaa ttaattaagg ttcttaaaaa
     4621 gataatgtag gttatattgt aggataataa atataaataa aattgagtat ttgtattctg
     4681 aatatatttt atttttaatt tggtatattt gttataaaag tggtgatttt gtgataaaat
     4741 ttaattatat agaaataagg aggaaaaaat gaaaattaat tggaatacaa aatacacaac
     4801 aatagcaatt tatacattta taatagctgc tagtagtatt atattttatc tagtatcatc
     4861 acaaattgat gtattttcta ataatttaga tgctatattt acaacattac aaccttttat
     4921 aataggattt gctattgcat atcttcttaa ttttatttta aagttttatg aagacagaat
     4981 ttttataaaa agtgagaaat taaaaaaact aaaacaaagt tcaaaaagag gcttgggtct
     5041 tttattaaca tatgcaacag ctacattgat actttactta tttatgcatt tcgtattgcc
     5101 acaagtaatt gagagtattg ttggactagc aaatgatata cctatgtatg taaacaatgc
     5161 aactaagctt attgataaat taatgactga tttaaatctt gatgagcaat actttaattt
     5221 ggcagttgat aagtggaatg agtttgttac atatattata aagtttgtaa cagatttaat
     5281 cccaatatta ggaagtatgt taaagaatgt agcctctagt atatggaata ttgtactagg
     5341 attaattgtt tcagtatact tattaattga taaagaaaaa ttctatggat taagcaaaaa
     5401 aataacttat gcagtattta cagaaaaaca agctgctaga attttagaat taactcatag
     5461 aagtaactat acatttggaa gatttttagg tggcaaaata ttagattcat tcattatagg
     5521 tattctaaca tttgtaatac ttacattagt taaaatgcca tatacattat taatatcagt
     5581 tataattggt attacaaata ttatcccttt ctttggacct ttatttggag ctataccatc
     5641 tacgctaata gtgatgtttg tatctcctat aaaagctttc tggttattgt tgattatatt
     5701 aataatacaa cagatagatg gaaatattat aggacctaaa atacttggag attcaattgg
     5761 tatatctgca ttttggattt tgttctcctt attggttgca ggaaaattat taggttttat
     5821 tggaatggtt ataggagttc caatgtttgc agtaatttat tctataatta aggatattgt
     5881 tgaaagtaaa ttggataaaa agggattacc gacagatact tccgattata tgtagctaaa
     5941 aaatattatg tataattaaa aatatataaa ttaagcaata tttaaagcac tgagaaagtt
     6001 aaactcttgg tgctttttag atataaaatt attatagaag aggtgttttt tgtggcattt
     6061 atagaatgta aatttaaatc taaatatact ggaggagaaa ctgatataat tgtaattttg
     6121 cctgtagcaa atggaaaaga actttttagt ggtaaagaga tatatgattt tgaaggtaaa
     6181 tttaaaacat tatacttatt tcatggttta gaagatgacc aaagctcatg gattagatat
     6241 actaatgtag agcattatgc taaaaataaa aatatagccc tagtaatacc aagagtagaa
     6301 actagttttt atactgatat ggcgtatgga caccaatatt ttacttttgt aagcgaggaa
     6361 ttacctaaat ttgttagagc tatatttcct ttatcagata aaagggaaga taactttgta
     6421 gctggtatgt ctatgggggg atatggagct ttaaaattag cgctttcaaa accaaaagag
     6481 ttttcggcag ttgcaagttt ttctggttcg cctgatatga ttcatgagtt agaaaatcaa
     6541 caaatagaaa ccaatgcaga cattctattt cacgattttg gtagaccaga agacgctaaa
     6601 aatagtgaga atgatttact ttacatactt aagaacctta aagaaagaaa tgaagatatt
     6661 cctaaaattt atcaattttg tggtgataga gattttttat ataaaaataa tcagatgttt
     6721 aaaaaatatg cagattctct gggtgtagat gttgaatatg aagagtgtgt aggggggcat
     6781 gaatggcgtc tttggaattt atggataaag aaatttatag atataattgg atagtacact
     6841 tatggtatta acaggtatac tataaaatat ctttaaatat gataaagact gaaatcctaa
     6901 aatcaaatta tgattttaaa atttcagtct ctaagaattt aataaaattt tattaagttc
     6961 ttacacgagt tattattgga gtaaaattgt caactatatc tatatagtat ttactcaatt
     7021 cctctaaaat ctcttcgcat aaatccgtac tatgaccaag attaataaga aactgttttg
     7081 taaaatgctt tattacagct tgagaagata tatcgtactt gtgtgaagta taaactctaa
     7141 ttatttcagg tttcatagca agtataccaa tacaagaaag tattaattca tcatgttcta
     7201 tagattcttt atcattaaca tatcttttca tgaccatttc ggttacactt ctttgatagc
     7261 ttaaaatagc ttcttcataa gctatatcca aataaaaatt tctatatgct tcgtttttta
     7321 gaaggaaaca aaggtcagca ttcatagcaa gaaagaacat catcatagta ccttcttcat
     7381 ggtagttata gattaaagac tgcatttcat ttcttatatc ttcatatatt atagctccta
     7441 tttcgctttt acttgagaag taatagctta ttagacctaa atttatatta gctctttctg
     7501 caatttgcct agttgttgtc ttatgataac cttgctcaaa aaataattct ctagcagcac
     7561 ttataatact agcttttgtt tctttgccct tttctgattt tgacatattt actgtatata
     7621 cctctctttt caatcttttt ttgaaaattt gctaactata aatattgtaa tagaaccacc
     7681 tattatagga accaaaattc tgtcaaatac agtaagaata ccaatcatat ttaataatgc
     7741 caatataaca cttactataa cagcatagat agctcctttt tttgtagcac ctttccagca
     7801 aagaccaatt acaaatggtg caaatattac acctgtacat aatggagctg gccaaaacaa
     7861 taattctaat aaactatcaa atttaagtgc tataattgca cctattatag ctgtcaaagc
     7921 tgatgcaatt tgagaatact ttagagtatt ttttaaatca ttaaattcta tattaggatg
     7981 taataatttg ttataaatat ctcttgatat aatagcactc attgaggtca ttaatgaatc
     8041 ggcagtagac attatggcag ccaatatagc agctaagaat aatacagata ttaaaggtgg
     8101 caaagtagtc gatatcattt gaggtaaaac ctgaacagat gatatatttg gaaataaact
     8161 accaccaata gctccaatta ttcctatagg gaaagcaaga aataatagta taaatcctgc
     8221 aattacacta cttttaactg catttttagc attatcagca cattgatatc ttaaaaaact
     8281 ttcataagaa aatattgagc ctaaaactaa tggtaaaact gtatacataa aatcactaat
     8341 cgatttattt cctggaaaga atggttcttt taccattgat tgtaacataa gtaaagggtt
     8401 gtcgccaact aattttaagc ttatataagc tactattggc aaaaacacta tacaaatagc
     8461 aagttgaata aatgctgata ctgcaactcc ccacattcct gatgtataag tatatataat
     8521 tataactata actcctataa ttacagctat atcataagga ataccaaatg cagtagatac
     8581 agaaccaaaa gaaatcaatt gactacccat aatagctagt atagatattg gtgttacaag
     8641 actttgataa gctcttaaaa atacactatg accatatcta gtttcaatat aatcagcagg
     8701 tgttatatca caagataagc ttcttaattt tcctgcgaaa aatgcattta taaagcaagc
     8761 taaagctgca cctatagtag aatacattcc aacccaaagt cctctttcag ctccccattg
     8821 aactccacca actaagcacc ctcctccaaa agatgtagca gcaatggttg cagctagtat
     8881 aggcaaaggc agatttctac ctgcgattag gaaatcggat gctgttttaa ctttttttga
     8941 aaaataaaaa ccaatccata tgtatattgc acacgtaaca attaaaagta acatagtctt
     9001 ttctccttta taaaatattt taataaaata tacaaaatat atttaaaata tattttatat
     9061 aaaagtagta cgatatttgt tttattggtt ttagattaat atagctataa taatttatga
     9121 tattagatgg aaattacgta aaaatagaaa attgaaaatt ctgaaatttt tgcatattga
     9181 tatttatctc atagattctt ttttgtaatt gtaacacgct tttattttta aatcaatagt
     9241 acatgtataa aaataaaagg aatttaaata agaaaaagat atttttaata tctggatgta
     9301 gtatagaaat atcttgaata aattattctt gaataaaatt ataaaaaatt aaaatcacta
     9361 gaaatatgat aaaataattt aaaatacgca tttcaatgac atttcaaaac aagaaaataa
     9421 taaaaaacaa acctaaatta agtctaaata gctttttagt taattttagt agtaaaaaat
     9481 aaaacttaaa aaatgtttga caattatgaa ttttgagaat ataattaaat taaaattata
     9541 cacatataaa aatatactcc tgaatcaaga atgagatatt taagattcaa aatatatatt
     9601 attatacgtg aataataaaa agtaagaaaa ttttataagg gaggggtaga tgtgagtagt
     9661 caagaaagca aaccaaaagg aaatcttata tcaaatttta gagatgatat gagagaccct
     9721 aagaaaagag caatatacac atattcaagt tctataaact tagcgtacaa ttttataggt
     9781 tactttgtat caactgttac aaatattttt ttaactgatg tggcaaaact tggtgtaatt
     9841 atggcaggtg gtatgcaaat tatacaatct ttcataaaaa ttgctgtagc tcctataaca
     9901 ggtacagtat ttgacaaaca accattcaaa aaaggaaagt attatccatg gcttagatat
     9961 gcaccagcag cgttagcatt aacatatgga atatttttca tagttccatt aatgaaaata
    10021 agtccagcat tacttttacc tttgatgaca gctttattat taatagcatc ttgtgctcag
    10081 caagtagttt tcactataat ttatgctatt taccctgtag ttgctaagac acctagagac
    10141 cgagttatag gctcaactac tacgaatata tttaaagaag ttggtaaatt cttagtaggt
    10201 ttttcatatc cgttattatt agttttattt gcagatgtat taggtggaga aggaatgggt
    10261 tatttaggta cctacttatt ctttgcagca ggatgccttt tagtattttg gttttcttca
    10321 acagagataa taaaatctgg agcagaagaa gaagttcttc aaaaagaaga gaagccaaag
    10381 attaaagcaa gtgaaatggc aaaagcttta ttcactaatg taccacttat gatggcattt
    10441 tgtttagaat ttcttatatg tataagatct ataggattag gacctttggc tccatattat
    10501 tttaaatatg taatagaaga tgaacgtgga ttagcagtat ttttatcaat catgcctttg
    10561 gtaagtgtag cattcatgtt tttcgcacca gtgtttataa aaatctgtag agagcaaaaa
    10621 ctagcttcaa taatttcttt ttctatatgt gcactatgcc acttattggt tgcatggact
    10681 ccttggggga aaactacttt aggagtaact atgttgttgg caattggtgg aggtttttca
    10741 aatgtagtat caataataaa tcttaatttc tttgccggtt cttgtgatta tgggcattgg
    10801 aaatcaggaa aagacttacc tggcttaagt atgtcactat atccagttgc aatacaagta
    10861 ggagtattac ttgcaactac tataagaaca gttttaatga actcaatggg atatcaagct
    10921 gatatggtag tcacagaagc agttaaatca ggttttataa atatgatttc ttattctatg
    10981 gcaatacctt taataatagc tgttgttata gcaatactat atccagtaag tgacaagaaa
    11041 ttaaaccaaa taagagaaga gttaaatcaa agaaatgctt agttaaaaga aagttgagta
    11101 gatggttaat ttaagctatt aaagtaagta gacgcaatag cgtttatata aatgaaaata
    11161 catatacaga gggggctttt aaaaatgata gaaaaattat tgagaaatac cgtaaaagaa
    11221 ttacatcaat atgttccagg tgaaccaata gaaaaagtta aggaaaaata tggtgtaaaa
    11281 gaaataataa aattagcttc aaatgaaaat cctctaggac catcaccaaa agcaatagaa
    11341 gctatgattg aaatgttaaa acaaggtcaa ctttatccag agccagaagc taacgaactt
    11401 agaagaaaat tagctgaaaa gctagattta aaaccagaaa attttattgt tgctaatggt
    11461 gcagataacg ttatcactct aataggtgag gcttttataa atagaggaga tgaagttata
    11521 tattgtaacc caacatttcc atcatataga actgcaacta taaaaaatga agggatacca
    11581 gtagaagtac ctttaacaga agattataag tatgatttac aaggtatatt agataagatt
    11641 acagataaaa caaaattaat atgtgtatgt aaccctaata atccaacagg aacaattgtg
    11701 gatgataaag agttagaaga atttttaaag aaagtccctg aaaatattat aactatattg
    11761 gatgaagcat atatagaatt tttaacagtt cctaattatg tggatggact taagtatgta
    11821 agggaaaatt ataacgttat agtaacaaga actttctcta aaatatatgg tcttgcaggg
    11881 cttagagtag gatatggtat tgctaaagat gagataataa gaactttatt tacagtaaaa
    11941 gagcctttct ctgcaaatcg tgttgctata agtggagcaa cagcagcact tgatgatgaa
    12001 gagtttataa aagaaacata tgaattaaat agagttggaa tggcttactt taaagaagag
    12061 tttacaaaaa tgggatttga tgttgtagat tcacaatcaa atttccttta tgtagatatg
    12121 aaaacagata tacctaagtt atttgaagac ttgaaaaaaa gagggtttgt aataagacca
    12181 agtgctacac atgcacgtgt aagtattgga actatggaag aaaataggaa atttgtagca
    12241 gttttaaagg aaatattaaa tattaaagga gagccaagta ttggataata gatagaaata
    12301 ttatgaaacg gggtgtagat atgaacttaa aaataaacgc agagagatgt aaaagttgtg
    12361 aatactgcgt tatatcttgt aaaaaaggag cattaaaaat atcaagtaag ataaataaag
    12421 aaggttatgc tcatgtagaa gttgatgaga gtaaatgcat actttgtgga atttgctatc
    12481 aggtgtgtcc agataatgtt tttgaaataa ttaaagaaga agcatgtcaa gaggcttaga
    12541 aggagttggg ataatatgaa aaagatgtgg aaggggaacc acgccattgc agaagcagcc
    12601 ctaagaggag gttgtgaatt ttatgcagga tatccaatta caccacaaac agaggtaatg
    12661 gaatttttat cacatagaat gtctgaactt ggaagaactt ttatacagtc cgaaaatgag
    12721 atggctgcta tatatatggt atatggagca tatgcaagtg gaatgaggtc tatgacgagt
    12781 tcttcaggac caggaatatc tttaaaacaa gaagggattt cttacttatg tgcaaatcat
    12841 tacccttgtg taatcgtaaa tgtacagaga tgggggcctg gtcttggctc attggactca
    12901 gcacagacag actatctaag agatactaga gggggaggaa atggagatta tcatttgata
    12961 gtttatgcac caaacagtat tcaagagact gtagatttga tgtataactc atttgatgta
    13021 gcggagaagt acagagtgcc tgtcgaaatt ttgacagaag cagctttagg tcaaatgatg
    13081 gaaccagtag aatttccaga gtttaagaag agagaaggag atttaggttg gacttatgat
    13141 ggaagtaata gagaccatgc aaaggttgca gataaccaaa agccaacttt ttgtatggag
    13201 aaacgtatga gaataactga aaatgaacaa caatgggaag attatcaagt agaagatgca
    13261 gaatatgtgt ttgtagcgtt tggtatacca tcaagaacaa ctatgaatgc tgttagaaga
    13321 cttagagaac aaggtgaaaa ggttggaata ataagaccaa taacagtatg gcctttccca
    13381 tataaagcat ttgaaaaggt aagtaaagat gtaaaaggat ttatctcagt agaatcaaca
    13441 gacacaggtc aattagtaga agatgttgct ttagcctcaa agaaagtatg taaagaaaat
    13501 gtacctgtgt atggtttatt tagtggaaat catataccaa aaacattgca agtaatggac
    13561 acttatagca aaataaaatc tggcgaaatc aaggaggtgt tctaatatgg ctacagaaaa
    13621 attaacacct agtgttgttt caataccaaa caagttttgc ccaggttgtg gtcatggaat
    13681 agtaaatcgt ataatagcag aggtaataga agaacatgga tatgaaaaaa atcatgtatt
    13741 aacattagga gttggttgtg tctgcaatat gaattttagc tggaatggtg ataagatgca
    13801 aactgcacat ggtagagctt catctacagc tataggagtt aaagtagcac ttccagatac
    13861 attagtaatg acttaccaag gtgatggaga tgcttatgtt ataggtcttt ctgaaacttt
    13921 aaatacagca tatagaaatc ataatgtgac tgtatttgta ataaacaata ataattttgc
    13981 aatgactggt ggacaaatgt catggaccac tatgccgggt caagtcacaa caacaagtgt
    14041 aaatggaaga gatataaaga ctactggtag tccactgaaa gttcctgaga tggtggcaaa
    14101 cttctttgat gtagcatatg tagcaagagg ttcagttcat agcccaaagg aaataattaa
    14161 tctaaaaaaa tatataaaaa atgcaataga agctcaatta aatggagagg gatattcctt
    14221 agttgaaata ttagcacctt gcccaactaa ctggggtgta tcactagaga aatctatcaa
    14281 atggatggaa gaagaaatag tgccatatta tgctcttggc gaatttaagc aaagggatgg
    14341 tgaatagtta tggaaaaaga gctagtattt gcagggtttg gtggtcaagg agttttaact
    14401 cttggtctga ttgtagctga gtcagcactt gaattgggga aacaagtaac ttggatgcct
    14461 gcatatggtc caactatgag aggtggaaaa gcctatagtg tagtaaagtt ttctgatgag
    14521 agtataggtg ggcctgatat ggaagaaata gatgttttag tagcaatgaa caaaccatct
    14581 ttagattata taaatttagt taaagaaggt ggaacagtag ttattaatac atctgcaata
    14641 gatgagaatg taacattaag agaagatata agtgtagtta aaataaattg tcaggaatta
    14701 gctcaaaaag taaacaatcc aaaagcagca aatatagtag tacttggagc attaattgct
    14761 aaaactgggt tatttgaaaa agaattagct ttaaaaacta tgtgtgattt ctttgaggaa
    14821 aaaggaaaag gaaagtttaa tgttcaaaat gaagcagcat tcatggaagg ctataataac
    14881 gccatttgat aaattaccct tatcttaagt gatttatctc aagatttaat aatctttagt
    14941 gccaagagaa acttcatctt gagataaaat tcacttaaaa tcacaactat aaacatatag
    15001 gagcgtgaat ttatgagttt ggaaaaactt attagaccaa aaagtattgc tatagtagga
    15061 gtgactgata aacttggttt tggaagaagt gcagcactta gtatagtaaa aagtaaggaa
    15121 acagatagag tatattatgt taatcccaaa agagaagaat tgtttgggag aaaatgttat
    15181 aagacgatac aagaagttcc agaagtagta gactgtgtag tagtatgtac gcctagaaat
    15241 gtagttccat ctgtattaaa agattctgga gagttaggaa caaaggcagc agtggtatat
    15301 gctagtggat ttgcagagga aggtacagag gaaggtacag atttagaaaa tcaacttata
    15361 gaaatatcaa atacatacga tatgaaaata ttgggtccaa actgcatggg gttgctaaat
    15421 tgtatagata aggttaatct atgggcagga ggttctaaat gggatttaga tactaaaaaa
    15481 cctggtatag gaattgtagg tcaaagtgga tttataactg ctgaaattgt ttcaagtgat
    15541 tattttaata tatcttatgg tttttcaaca ggaaatggaa atatagttac actagaagat
    15601 gcagtagatt tccttgtaga tgatgattat gcatcagtaa tagcaattta ccttgaaggt
    15661 ttaaaaaatc ctcaaaaatt tatagatgct ttaaaaaggg cagcacaaaa aagaaagcca
    15721 gtaataatat tgaaatcagg aaggtcagaa aaaggtgcta tttctgctgc ttctcataca
    15781 ggaaatctag ctggttcgag taaagctttt gaaagtattt ttgaaaaata tggagtaatt
    15841 tctgtggaaa atttagaaca gtttatgtgt ttagcacaag cttttagtgt tttagatggt
    15901 aatttacctg caaattctaa ttttgcagca ataaacttct caggaggaga aaatactatt
    15961 tgtgcagatt tagcagaaga aaatggtgta gaacttgcag aaatatcttc tgaaactaaa
    16021 gaagaaatga aaaaatatct tccaggattt gcaacaccta aaaatccact agatgctaca
    16081 acagcattat tccatgaaaa ggatatgata gtaggtttat tacatacctt tgaaaaggat
    16141 gatagtgttg gatttactat ggtaggtgca aatataagag atgaagaaaa tgaaatgcat
    16201 gaaacccttt gtaaagctgt aagtgaagct agagaacaag gattgaaaaa acctgtgttt
    16261 gcagttccta cacttgaagg aaatagatat ttagattata ggactagatt agaagataat
    16321 caagtgccta taatgtcatc agttggaact acatttactt gttttaataa aatggctaag
    16381 tttatagatt atgattattc aaaaagaact ttagaattta aagctgttaa gaaaagagag
    16441 tcaaataata tagtagcatt atcagaatta gatagtaaga ttgagatgaa aaaatatgga
    16501 gtaccagttc caggacaagg taatgcaaaa agtattgatg aattagatga aatcttaaaa
    16561 tatattaagt atcctgttgt tttaaaaata aattcttctg aaatattgca caaatctgat
    16621 gttggaggag ttaaaatagg aattaagaat agagatgagg cagtagatgc atataatgag
    16681 attttaacta atgtaaaaaa agcaaaacca gatgctaata ttgatggtat attagttcaa
    16741 gaaatggtag aaagtggtat agaaattatt attggtataa ctaatgatga ccaatttgga
    16801 ccaatgttat tagtcggttt aggaggagta tttgtagagg tatttaaaga tactacatta
    16861 tatccattac ctataaatca tgatgaagct attatgatgc ttaaaaaact aaaatcattt
    16921 aagcttttaa atggctatag aggaagtgag ccttgcgata ttgatgctct tgcagatatg
    16981 atggtcaaat taggaaaata tgcttatgaa aataaggatg aagtcaagga aatagactta
    17041 aatccagtgt ttgtatatcc taaaggaaaa ggcgtatgtg cagtagatgc cttaatagtt
    17101 aaatataaat agtttataag ttttggtatt caaccataat taaagcaccg actgaaaatc
    17161 acattttgta agttagatag tgtgattttc agtcacccca aatttaattt aaaaatattt
    17221 taaaatgaaa gtatagtttt aagtttcatt gtgaaatagc actgtataaa caataaaata
    17281 ctacgtataa aacgaataat aaaaggtgtt ttaatgataa gaatcaatct tgattttcat
    17341 taaaacaccg tctttattat attaaaaatt tttaaacatt atattgtcac aggtgggttt
    17401 gttggagctg catatgtacg attagcaaat tcttggtcaa caaagaatag accaccctct
    17461 ccagcaagtt taacacgttt tatattgtct tcacaatttg tctcttcttc tgcttgttca
    17521 gatataaacc aaagtaagaa ttgagaagtt ctaaagtctg attcagagtt tgctacagct
    17581 gctaagttgt ttattaaagc tgtaaccttt ttttcatgag ctaacgtacg ctcaagaata
    17641 tccattgcag aagtaaagtc tgaatctggc attgggatag catcaagctg aacctttcct
    17701 cctacattat gtaagtattt gtaaaaaaac atagcgtggt ctgtctcttc tttatattga
    17761 acataaaacc aattagaaaa tcctttaagt ccttctgctt caaggtaaga agacatagaa
    17821 agataaagat acgcagaata taattcatgg ttaatctgct cattaagtaa tttttccatt
    17881 ttagctgaaa tcatttttat acctccaaat tttaaatgct cttataaaat ataataatat
    17941 taaatggaaa aatattcaat aaaagtgttt aaatatttta catatttaat aaaaatttat
    18001 actaccatta aaaaaattat aacttacaat ggctatagag ccaattaatg gtgcatttgc
    18061 tccaaaattt gaatgcctta cacttatttt tttatattta gaaaaacttg ctgaagcagt
    18121 caattttttt aataatgtat tttctataaa tgtaccaggt atattaaagt catagcctat
    18181 tattatagaa ctacaatcaa tcaatgtaag tgtattaact aatgcatatg atacgtatgt
    18241 acaaaattca tcaagcaaaa acatggcaag actatcttta ttatttgcct catctattaa
    18301 cttgactaaa gaaaaatctt tacagttaat taatggggag ttaggataaa tatggctcaa
    18361 tgattcaatt cttttaatta gattactgac acttgtataa taatctaaac atccattgtt
    18421 accacaactg cacaatggtc cactaaaatt aattgatgta tgtcctattt ctccactttg
    18481 tcctaggttg ccagtatgaa gtttattttc tagaactaga ccagctccaa taccattcat
    18541 tatgtgtagg tatatataat ttgatatatt tttacctaaa ccatacattt tttctgctaa
    18601 tgcacctgaa ttagcatcat ttatcaaaaa tattggcaaa tcagacattt cttttataaa
    18661 atctactata tttaggtttg atacatttcc aaaatctggg ggatttagta tggtaccatt
    18721 tatatcatct actggaccta ttgaagaaat accaattcca attatatctc tcttgttgat
    18781 tttcattatt ttagtaaaca ttctttttat tatatctttt aaaacatcat ttgatagaca
    18841 tttagggtaa gtttcagaaa gttgttttac aatattacct tttaaatctg aaataattac
    18901 cttacatata tttcttctta ttaggattcc acaaatacaa ggcgatatat tagaaatatc
    18961 taataaaatg ggtttacgac ctgatgaatg tgcatttaaa gttgatgact ctatttccct
    19021 aatcatattt tcattaataa gttcagtaac tagatttgat aaagtcattt tagtaagtcc
    19081 tgtagactta gctaaatcaa ctctggacat aggtgtattt gtagaaagta atttcaatat
    19141 tattaactta tttttaattt ttacatcttt gatgttagaa ccttgtttgt tactcatcat
    19201 aaatctcctt aaataaagtt aagtgtttta tttattttca agtatactat caccttataa
    19261 tagagtaaca tttttttact tgaaaatatc attaattaga atatatcaca ttatatatca
    19321 taaaatatat agaaaaatgt tagaattaaa ttaaaagtga aaagtagatt gatatataaa
    19381 tagtaaatac ttaattaaaa aaagataatg atagcaataa ttattgttac caagaatcta
    19441 ctacttcaag tgttacctta ggtatttaag ttgatagtgg tttgcacgta ataaacttga
    19501 tgtaatatat attcttaata atattgataa aagatttact taaaaataat atagattatg
    19561 taaacatata atctatttat tgtatacaat aaaatttcat tttgtaaaac agtgaattaa
    19621 atatgtaata tagatatcga tttttattac aaattgttac taaatatagg tacattagaa
    19681 caaaaatcta gtaaattgta actaaaatgt aaatttttcc tttaatctat acaatattat
    19741 ggaaactttt tgtaatttat gatataataa caaatatata attattaaat tataataaat
    19801 gactatagcg tagatgtaat actatgttat agtcattttt gaattaaact tgatatatca
    19861 agggggaaga atatgagaac aattagaaga gttttagcat taggtttaac attagctata
    19921 tttctaataa atgtacctaa tgtagatgca ttaacatcag atacaattaa aggtaacaat
    19981 atatatgaga cggctggatt aatagcagat aaaaagagtt atgatacagc aattatggta
    20041 aatatggata attctatagc agatggtctt tcagcaagtg gtcttgcagg tgctgttgat
    20101 gctccaattt tgcttgcaca aaaaaataag ataccaaatg aaacaaaaca aagattaaaa
    20161 aatgttaaaa agatatacat aataggtaaa gaattatcaa taagtaagtc agtagaaact
    20221 gaactaaaaa acacaggagc acaggtaact agattgggtg gagatgacag aataaagact
    20281 agttatagtg ttgctaaaga ggtaaatggt atcaaaaaag ttgatgaagt gatattaact
    20341 aatgcatata aaggagaagc agatacaata agtgctgcac ccgtatcagt aagagatata
    20401 gctcctatag tacttacaga tggaaagagt gtgccttttt caacaagcaa tgtaaaaaca
    20461 tatgcagtag gtgggagtat atcaatgagc actagtttag ttaataaaac taatgctaaa
    20521 agacttggtg gttcagatag atatgataca aataagaaag ttataaaaga gttttatcca
    20581 gatgcatcag aattttattt gagtgatgga tatgatttag taaatgcact tacaggttct
    20641 acaattgcta aggaaaatcc aattgtattg gtgtcagaaa gtagtgataa gtctatatta
    20701 gcaggagcag ataagattac tagattaggt tcaataagtg acagtgtgta taataagtgt
    20761 gtttctgctg cacaaaataa tggcgattcg tctacaaaag gtgaatcacc tatgaaaaat
    20821 gagacaagca tattaggtca gccaacagct agtttagaag cgtgcttaaa atgggcaaaa
    20881 tctaaaaaag ctaatgattt atttatagag ttaataccaa tattatatga tactgctgtt
    20941 caggaaggtg ttaatcctgt tttggcagta gctcaatctg caaaagaaac tggtttttgt
    21001 aattttggtg gagtattaga tgcatcattt aagaatcctt gtggacttaa aacttctgta
    21061 ggtggttctg atactgataa gaatgcccat tcaagatttg atacttggga agaaggaata
    21121 ttagctcaaa ttcaacattt atgcttatat gcaggacaag atggttaccc actttcaaat
    21181 ccagtagacc ctagacatga aaaatcttta tttggtaagg ctaaaacagt tgaaagttta
    21241 tctaataatt gggctggagg tcaatatgga caagatttag taagaatgat gggagaaatt
    21301 gaggcaacaa aataattgaa gattatcaaa tatccaataa ataaggattg attattatga
    21361 aaaagagtaa tatttttagt atcatatttc ctacagtcat aatggtgcta atgtttttaa
    21421 cttttgctac agatatattt aatattccag atattcaatc taaaagtatt tttgttgtgg
    21481 gaatggtttt gatttttcca gtttcttttt tgatacaagg gataatttgt gtattaaata
    21541 agactaattg gattttatct cttattgtgt ctttagtaac ttatatagta ttaatgtata
    21601 tatttttaaa tgattctgca tatatatatg ttttacttta tacagctttt tatatgattg
    21661 gacatataac agctaaactc tattacaaaa ttaagacttt taaaaattaa attgaagtat
    21721 ataaaagtaa cattaggaga agtatcctta atgattttct aaaatcagaa ataggtgctt
    21781 ctcttttttg taaaaataaa agtatgtaaa taaaatttaa ccattataat tttcttttaa
    21841 caaatgtata caataaactt gttgtataat taagatagat aaaataaagg gagggataat
    21901 atgaatttaa tagataatca tattcatact aatttttcaa gtgatggaaa ggattccatg
    21961 gaagatacaa taaaaaaagc tataagtatt ggtgttagat atttgacttt tacagaccat
    22021 ttagaacatg atgaagatag aggattttgc ataaattata atgactatgt tccagtattt
    22081 aataagttta aagaaaaata taaaaaggac atagagttat tactaggtgt tgaagtgggt
    22141 tacagaaaac atctaaaaaa tgaaatagaa gaaataataa attctaatcc ttttgatttt
    22201 gtattgtgct caactcatac aattgacaat gtacctgttc catcaaaggc gtattttaaa
    22261 ggtcttagca aagaagatgc gtattataaa tattttaata gcatacttga aactaatcgt
    22321 gaatttggag attacaatat atatggtcat ttggattata tatctaggta tggaatatat
    22381 tcagataata gagttatata caatgacttt aaagatgtta ttgatgaggt cttaaagtca
    22441 ataatcaata atgggagtgg tatagagcta aatacttctg gttatagata tggattaaat
    22501 gctatacatc caaatgaaga tattctaaaa agatataaag aacttggagg atttatagtt
    22561 actgtaggtt ctgattctca tagggtagaa gatatatgta aagattttga tgtggcctat
    22621 gatatgctta agtatcttga ctttaaatat gtatctttat ttaaagaaag agaaacttat
    22681 tttgtaaata tagaaaaagt taaatctaac aatatagctt agagtgtgtt ttgaagtaaa
    22741 ttaatggata gttaaaaagt taatagttat aatattgtat cctctagaaa aatactagag
    22801 gtttttattt tgctaaaata actaaataga attaaattta aatagtatag cttattttaa
    22861 attgaatagt ttattgttg
//
LOCUS       DAEPXW010000063        22367 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.064, whole genome shotgun sequence.
ACCESSION   DAEPXW010000063 DAEPXW010000000
VERSION     DAEPXW010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22367
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.064"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(138..1328)
                     /locus_tag="KRM55_002422"
     CDS             complement(138..1328)
                     /locus_tag="KRM55_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1594658.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKISYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(1588..2019)
                     /gene="dut"
                     /locus_tag="KRM55_002423"
     CDS             complement(1588..2019)
                     /gene="dut"
                     /locus_tag="KRM55_002423"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBH1594659.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            2132..4360
                     /locus_tag="KRM55_002424"
     CDS             2132..4360
                     /locus_tag="KRM55_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBH1594660.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(4471..4956)
                     /locus_tag="KRM55_002425"
     CDS             complement(4471..4956)
                     /locus_tag="KRM55_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1594661.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            5208..6431
                     /locus_tag="KRM55_002426"
     CDS             5208..6431
                     /locus_tag="KRM55_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH1594662.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            6435..9569
                     /locus_tag="KRM55_002427"
     CDS             6435..9569
                     /locus_tag="KRM55_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBH1594663.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKSDTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            9603..10901
                     /locus_tag="KRM55_002428"
     CDS             9603..10901
                     /locus_tag="KRM55_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBH1594664.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(11190..11435)
                     /locus_tag="KRM55_002429"
     CDS             complement(11190..11435)
                     /locus_tag="KRM55_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1594665.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(11649..14276)
                     /locus_tag="KRM55_002430"
     CDS             complement(11649..14276)
                     /locus_tag="KRM55_002430"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH1594666.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(14337..15179)
                     /locus_tag="KRM55_002431"
     CDS             complement(14337..15179)
                     /locus_tag="KRM55_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBH1594667.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(15186..15824)
                     /locus_tag="KRM55_002432"
     CDS             complement(15186..15824)
                     /locus_tag="KRM55_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594668.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(16260..17552)
                     /locus_tag="KRM55_002433"
     CDS             complement(16260..17552)
                     /locus_tag="KRM55_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH1594669.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDIAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(17589..17945)
                     /locus_tag="KRM55_002434"
     CDS             complement(17589..17945)
                     /locus_tag="KRM55_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH1594670.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(17980..18339)
                     /locus_tag="KRM55_002435"
     CDS             complement(17980..18339)
                     /locus_tag="KRM55_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594671.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(18408..20381)
                     /locus_tag="KRM55_002436"
     CDS             complement(18408..20381)
                     /locus_tag="KRM55_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH1594672.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(20603..21616)
                     /locus_tag="KRM55_002437"
     CDS             complement(20603..21616)
                     /locus_tag="KRM55_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBH1594673.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINEQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(21629..22174)
                     /locus_tag="KRM55_002438"
     CDS             complement(21629..22174)
                     /locus_tag="KRM55_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH1594674.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT         7667 a         3723 c         2891 g         8086 t
ORIGIN      
        1 agagaaaata aataaaaagc aggtatcaat caaatagtaa catgtattat actatacatt
       61 actatcaata ttgtacctgc tttcatatta taagcaataa agaaaaatct atttattagg
      121 ttttataata aaaacaatta taaaactctt cttgcattta catatctact tgaatagtag
      181 ctactattta tattagatat tgttactttt tttgatgaac ctgaagatgc atgtatcata
      241 tctccatttc ctatgtatat tccaacatga cttacagaac cattatttga accttgtgta
      301 tcaaagaata ctaaatctcc acttctaagg tctcctctat ttacatatgt tccatactta
      361 ctttggtctc tagatactct tggtatacta actcctacag attttttcat aacgtactgc
      421 gtgaatccag aacagtcaaa actatttgga ccttctgctc cccatacata tggttttcca
      481 agtagtgtct ttgcaaaact tattacacta tcagctcctt gacttggaga attagtcgaa
      541 taagatggaa ttgaagtatc aacagaacct ttttcagcaa ggtattgact tgacacatat
      601 ccagtttgat tgccataact tatttttgtc catcctccac tttcagaaat acttccaacc
      661 tcagtaccat aacttaatgt agctatttta gaatgacttg tacctggtcc tgttctaacg
      721 ttcaatgact ttgctgttac aacctttgta ccctttacaa ggtcatttga actgttttca
      781 gcattttcat ttgtagagtc atttacacta gttcctaaat atttacttga aacataacct
      841 actctaccat tagaacttat ttttgaccat ccatttgact cagatatgta tccgacttca
      901 gtcccatatc ctagtgttga tattttagaa ctacttgtac ttggtcctgt tctaaaattt
      961 aatccttttg ctgttacaac ttttgtcgac ttaactgaag tatcactact ttcattgcta
     1021 cttccaaggc tatttattgc tacataattt ccatgcacat aacctgtgtt tccattatat
     1081 ttaactttta cccaagaacc ttcttttcct acgtactcaa ctttatcacc tttgtaaagt
     1141 ttccccattg attcatggtt tgtacctggt ccttttctaa aatttaccgc attccctgtt
     1201 attgttctgc tttctatact cacactctct acttcagact cattagcata tgctaaattc
     1261 cccatagtag gcattattat cgcagttgcc attatactgg ctgctattct cttttgatta
     1321 aaattcataa ctttccactc atctcctctt ttctactatc tttatttcac ttcaaaatat
     1381 aaaagaaata attgacacta tcaaaatatc aattatttct tttatattaa tattattaca
     1441 aatttgtaac tatttgtcta tagtaatatt tgcttaccat aaattaccat gtataaattt
     1501 taatctttaa tagcctgtaa tttagtaata tagccatctt ttaccttttt taaaaatggc
     1561 tatatttttt aacttttttg taacttttta aaatccagtt gagccaaacc caccttttcc
     1621 tctttcggag tcacttaatt cttttacttc ttctatgtta atatcataga taggttttac
     1681 tatcatttga gcaattttca tatgcttttc aaccttaaaa tcatttttac catgatttat
     1741 taatataatt ttaagctctc ctctgtatcc ttcgtcaata gttcctggtg tatttaatac
     1801 agtaacagaa tgctttaagg caagcccact tctaggtctt acctgcgctt ctgtcatagt
     1861 aggaagctct atacatatcc cagttttgat aagtttagtc tctccaggag gtattacaac
     1921 ctcttctata gaatacaaat ccataccagc atcacctttg tgagcaaaat taggtattat
     1981 agcatcatca tttaattttt ttacttttaa attgtacatc ttatatctcc tttcaacttt
     2041 ctataaatat tataacttaa atttcgacct cttgaagttt tttatttttt tgtggtaata
     2101 taattattag tgttttaaag gaggattttt tatgaaactt gtacttgctg agaaaccatc
     2161 tgtggcaaaa actatagcat catttttagg tgcaaagacc agacaagatg gttactttga
     2221 aggaaatgat tatataatta cttatgcagt tggacactta gtatcattat atgatatgaa
     2281 ggattatgat aaagataaat actctggctc ttggaaaatg aacaatttcc catttgttcc
     2341 tgaggataag tttaaattta agattgatag ttctaaaact aaacaattca acactgtaaa
     2401 aaagcttttg aatagaaaag atgtagaata tgtaataaat gccactgata atgaccgaga
     2461 aggagaactt atagcatttt taatattttt actggcaaaa aataaaaaac cagtaaaaag
     2521 aatcttggta aatgaatgga caccagaaga tattacaaga ggtataaaaa acctaaaaga
     2581 tgaagatgaa atgagaaatc ttcaagctgc tggatatact aggcttatta ctgactggtt
     2641 gattggaata aatttcactt ctgttgctac attgaaatac ggaaatggga aactattaaa
     2701 cataggtagg gtaattcttc caacagttaa attagtctat gatagagata tggaaatact
     2761 aaactttgtt cctaaaactt attatgaaat agaagggcat tttaaagctg aagctggtga
     2821 atataaaggt aaatatgtta agggtaaaga aagtaaattt gatacacttg aagatgcaaa
     2881 taaaattata gcttcaatta catctgaaac tggtaaaata ctagataaaa aagttactat
     2941 gtcaaaggaa tatgcaccaa aactttttag tttgacatca cttcaaggat atataacttc
     3001 taagtattcc aattttacat ctgataaggt tttaaatgtc tgtcaatctc tctatgaggg
     3061 taatggtaag ggtggataca taacttaccc tagaactgat tccattttct tagaagaaag
     3121 tttggcttca aaagcttctc aaactttaga taaattaaag gttggtcttg aatatgaaaa
     3181 taaaattaaa ttttctaaaa ctaaaagagt ttttgattct tctaaagtag actcccatag
     3241 tgctataatt ccaacttata taattccaaa aagtttatct aaggatgaac aattagttta
     3301 tgatgccata aaagatagat ttgtagcaaa ctttatgcct cctgctgaat atgagaatac
     3361 agaaattaag actgaagtag ataattgtac tttcttaaca aaaggtaagg tgcttaaatc
     3421 aaaaggatac cttgaggtat ataataagga agaaaaaaac gatttacttc cacttgtaaa
     3481 taaagatgat gttgtagatg tgttagaaat aaaaccatta actaagcaaa ctactccacc
     3541 taaaccgtat actgaggaca cacttttaaa ggctatgaaa aattgtggta aaaatgtgcc
     3601 tgaagaagat acaacagtgc tatctggata ttcgattgga acatcagcca cacgtgctga
     3661 tgtgttaaag aagataagtc aagtgggcta tgtaaagaaa aaaggtaaat cttattctat
     3721 aacagacctt gggaaaaatt tagttgaaat ttttcctgtt aaagacttat ttgatgtaga
     3781 ttatactgga aaacttgaaa aaagtttaag cgatattcaa aaaggaaagt atacaagaaa
     3841 agaatatctt actaatatca ttagttttat atatcaaaat gtcaatatta taaaacaaga
     3901 tgcttcaaaa aatataaaca cagaagcata tactttcgat tcaaaaacta aaaaatttac
     3961 taaaacaaaa gaaaaaaaac agaaaaaaga tgtaactaat actgaaaaag aagttgctat
     4021 atcaaaggat tctaataaca aaaaagaagt taaaaatggt gatgaaaatc aatctcttgg
     4081 caaatgcccc atttgtcaag gtgatgtact agaatttgac aaaggctttg cttgtaaaaa
     4141 tcataaagaa tgtaaatttg ttatttggaa aaatgataag tatttaagtc tttataaaaa
     4201 gaaagttaac aaaacaatgg tcaaaaatat tttaaaaaaa ggtgaaacta aagtaaaatc
     4261 tttaactgct aaaaacggta ataaatttga tgctacatta aaatatgata aaaatccaga
     4321 tactggctat ttcaattgga aaatagagtt tgacaactaa atattcataa gaaaagaaat
     4381 agcagtagta taataatcta tattatatta ctgctatttc ttttcttatg aagtttcaac
     4441 ttttttaata gtgactttta caatcacact ctaacctaat ttctttacta tttctgataa
     4501 ctttaatgta tgttcatcta ataaagttag ttcctcttca gaaagattag ataatttttt
     4561 tactagagat tctttgagaa tagcttttac tgcatcaaat aatttaaatg ctttatctgt
     4621 taattcaacc ctaagaatcc ttctatcttt tgggtcagga aatttattga ctaaaccatg
     4681 ttccactaat ctgtcaataa tcggagtcat atttgatttt aaaattccta aattagaagc
     4741 tatttgagaa attgatgatg aatttgatgt cataagataa agaattacct tagcatgtga
     4801 tggagccatt ggacattctt caaaataagc tttcattata tcagagttat tttgaaactt
     4861 ttttaacaaa tcgctttctt taaatatatt attttcaagc acaaataaaa aatctaaaaa
     4921 agagtccgct attttaagta tattgttgtt atccatattt gtaacatccc ttcaatagat
     4981 aatataataa aacattgttg tttaatatag tataaattat aaactattaa taaatttaaa
     5041 acaagaaaaa gttattgact cataataatt ataaatttat aatcaaatta gagaattata
     5101 aattgccaat aaagggaagt tttttaatta gtctaaaact aaacttaaat tataagacac
     5161 tttaaattct acaacaagct agtgtgcaat atataatagg aggagatatg aaaagatatt
     5221 taatagtttt cttaatgtgt agttcactgt ttttagttgg atgtggaaaa acagaagaat
     5281 ctgaacctga gaaaccaata gcagtttctg ttcaaaaagc aataggtgga gaaattgaaa
     5341 acacaaattc tttctcagga actacaaagg ttaaagatga aacagctgtt actgcacaga
     5401 ctgttggcac agttcaagaa gtgtatgtaa aacttgggca aaatgtaaga aaaggagatg
     5461 aattattgag tataagcagt ccagagctag aaaatagtgt aaagcaaagt aaagcctcac
     5521 tagatttagc aaaagcaagt tattcaagtg ccactggtgg ttcattagag gcacaagtaa
     5581 atcaggcaaa aacagctctt gacaatgcaa agattcaata tgaggagtct caaagaaatt
     5641 atgacaataa taagattctt tatgaacagg aagtcattag tttagaccaa tttaaaaaaa
     5701 tagaattttc tttagagcaa acaaaacaac agttagattc tgctcaaaga gcatacgata
     5761 cagcaacttc aaaaagtata cctcaagcta aagcacttgc taaaaaacag cttgaccaag
     5821 ctcaagtatc atataattta gcaatgagta atttagacaa attaacatta acatctccag
     5881 tagatggtac aataacagct aaaaactttg attcaaagga aatgataaca caatcacaac
     5941 cagcttttat tatttctaat cctaatatac tagaagttga tttaaatgta gcagaatcag
     6001 atataggtaa atttaagaaa gatggaaatg tagatgttat aattgaagac caaaggattt
     6061 taggaaaaat agattatgta ccttcagtag ttgaccctca gacatcttta tatcctgtta
     6121 aagtacttgt aaataataca aacaacaaat ttaaggcagg tatgtctgct caagtaaact
     6181 taagtgttga aaaagaaaat ggtgctgtta cagtacctaa aaaagcaata tttgaagaaa
     6241 atggtaaaaa atatgtatac atagcaacaa aagacaatat agcaaagaaa cacttggttc
     6301 aaactggaat tgtaacagag gataaaatag aaattaaaag tggtgtaagt gataaagata
     6361 cagtgattat tggagggata agtcttattt ctgacggaac taagatattt cctgtagaaa
     6421 aggagaagta gactatgaat ttaacacaga cttccgttaa acgtcctctc acaatcataa
     6481 tggtcttttt agtattaata gtttttggtg gtattggata taaaaaaatg tcaataaatc
     6541 taatgcctga tatagaaata ccagttgtaa tggtcatgac tacttggaca ggtgctggtc
     6601 ctcaagacgt tgatgaacaa gttagtcaaa aagttgatga aagtttatct gccgtttcaa
     6661 atgtaaaatc tactatatca agttcacaag aaagtgtttc tatggtagtt gctcagtttg
     6721 aatttggaac taatttggat gaaataatga atgatgttag gtctaaagtt gatgcattac
     6781 agaccagcct cccagatgat gcagctaaac caacagtttt aaagctggat atgaatgcac
     6841 aggctatagg tcaacttgtc atatctggag gaaatgaaaa tagttcacaa gccttaagaa
     6901 aatacgctga agatgtaatt cagcctaaaa tagaatccat agatggtgtt acttcagcag
     6961 accttaaagg tggagaaaaa gcacaggtta atgtaatagc tgacccagct gttctttcaa
     7021 attatggagt tagtttatcc actataaaag gtgtcttatc ctctagtaat aaaacattcc
     7081 cttatggttc aattactcaa ggtgaggata aaatagtttt aagagcgatt gataaattag
     7141 aatccctaga tgatataaaa cagattcaaa ttcctgtaaa aggaggaaat acagttagat
     7201 tagataatct ttgtagtgta gattatggat atgcagacaa agatagtatt tatagataca
     7261 atggaaaaga cagtttggta atagatattt ctaaacaaca agatgccaac actgtaaaag
     7321 ttatgcagag tgcatacaaa tacgtagatg aattgaataa ggaaaatcct caatttaaaa
     7381 ttaaaattgc taatgataca agttcataca taagtgaatc aataaacagt gtaatgagca
     7441 acttgcttat aagtgctgtt atcgcattta ttgtaatatt tgctttccta aaaagtgtaa
     7501 gagcttcact agttgttgca gttgcaatac caatttctat aataggtgct atagcaattc
     7561 tctactttac tggtgaaagt ttaaatctta ttactgcaag ttcattggta atttcagttg
     7621 gtatggttgt tgataatgct acagttgtaa ttgaaaatat atttaaatat aggaaaagtg
     7681 gtagattgag tcttgatgat tgtgctattg agggaacaag aactgtaaca aatgcaatac
     7741 ttgcatcaac attgaccaca atagcaatat tcttacctat catgtttaca gaaggtatag
     7801 ctaaaataac ttttggggca ttaggtaaaa cactaatagc ttcactagca ttctccttta
     7861 taggtgcaat tacactcgtt cctagtgtat ttgcaaaatt aagcagagga aaaaatagtc
     7921 aaaagatgca agaaaaagat agtcctatat ttgataaggt aagtgaagca tataaaaaat
     7981 tattaagtgt atgtttgaga catcaacgct tagttgtaat atcaagttta cttatttttg
     8041 tagcttcctt atttggaatg ggatttatag gtatggactt tatgcctgca gcagacaagg
     8101 gtgaattatc tatttctata gaacttccaa aaggtcttag cctagaatcc aatgattact
     8161 atgtatctat gactgagaaa aaagtctcag atattccaga aattaaaact ttaataacaa
     8221 ctttgacatc agattcaaat aatagtaaag caagtatagc aattgaatta gaatctcaaa
     8281 aaaatagaaa aagaactact gatgaaatag aaaaagagat aattgataga gtggctactg
     8341 taccagattg taaaataaat gtaagtcaaa acagtagtgt tatgggtgga gctggaggag
     8401 cagacttcac attagaaatg aaaggtcctg atttagatgt attaaaaata ctgggaaaag
     8461 aagctgaaaa agaatttagc tctataaaag gatttagaaa tgttgaaact tctcttacag
     8521 atacaacaca agaagctcaa tttactatag ataaacataa ggctcaagaa tatggtgtaa
     8581 atactgctga aattgcaggc atgttacgta cagcaataaa tggtgactcc gtaaccactg
     8641 ctactattga tgattacaaa gtggatgtaa acctaaaatt taaatcagat actattgata
     8701 gcttagaaga tataaagcaa ctaaaagtaa actctgcaac tggaaaagaa gttcctcttg
     8761 gtgctttttc agatataaaa atggcagatg gtctacaatc tatatctagg actgatggag
     8821 atttttctgt aaatataact gctacacttg acaatttaga tgctggtact gctacaaaac
     8881 tagcactaga aaaaacgaat aaaatggtaa ttcctaaaga ttactctata ggtgttggtg
     8941 gtgaaacaga aatgatgaat gaatctatgg caagtcttgg attttcaatg gtcatagcta
     9001 tagcattagt ttatatggta atggtagctc agtttgaatc atttagtaaa ccatttataa
     9061 tcatgttctg tgttccattt gcattcgttg gagttgtgct ttcgcttcta gttagtggtc
     9121 aaagtttaag tactgtcggt atgctaggta taatcttact tatcggtatt gttgttaata
     9181 atggtatagt tcttattgac tacatagagc aacttagaaa aacaaatcgt aacaatgatt
     9241 taattggttt ggtttcaatt ggttgtgcag caagattaag accagtctta atgactacag
     9301 caacaacaat tttaggtatg ttgccaacag cactatctct tggtgaaggt ggagaaacta
     9361 tgcaaccact agccatagtt ataatgggtg gtctaactgt atctacactt ataactttgg
     9421 tgcttatacc tactatatac ttaatatttg ataaatggga aaataagttt tcagacaaaa
     9481 tgcctaaaat atttggtaag ataacagata aaataggaag tataaaacgt aaaataataa
     9541 agaaaccaaa attgaaagct aaagtttaaa tagaatggag ggtgattgta ttgaataaaa
     9601 aaatgagcaa aatagttgca attggctgtg gtgttggtat aataactgcc aatttaatcc
     9661 cagtttacgc agataataat acttcttcta taaacaaagt tgataattct attttaagtg
     9721 actcaaataa aagaacatct gaaaaggaaa ttttgactgc tagagaagct gttagtgctg
     9781 cacttaaaaa tagtgaaaaa ttaaaaatga aatcagaaga aataaaaatg ttaaaagaaa
     9841 agttagaagt acaagatgag tttgatagtt ttactggaag tgacaactcg tttccatacg
     9901 accaaattgg acttcttaaa aatcaaagtg aacaggctaa aggctttatg gaggaccaaa
     9961 tagcaaatga tattactaat aaatttaacg atttagtttc aagagaaaat gagctagata
    10021 agataaaaaa caatcttgaa ataaaaacta aagaaattaa agatatgaaa ttaaaaaaag
    10081 atttagggtt agtaacatct ttagaaactg aatcagctga acttgaactt caaacactac
    10141 aaaatactca aaaagctaaa cttcaagaac taaaaaacaa tcaagactat tttaagttat
    10201 taactaatat agatttaaat aattatcaat tggataaaga atatagattt gaatctttta
    10261 gagtaggtgg ctcagttgat tcatatatgg aaggtaaggt taatgaatat ttaaaatacg
    10321 accaattgat tttagaacgt acagaagaaa gctttaatga taaagatgag aacaaagcag
    10381 atttaccaga tagacctaac cttacaagac cagttgctcc tacaaaacca gagcaaggta
    10441 acctaactga tgatgaatac aaggttctta tggataagta tgaaaaagat tatgatagat
    10501 ataaaaaaga agttgaagca tacaatcttg aaagacagac ttatgctgct ggtcttacta
    10561 cttatgcaaa ttatcttcaa caaaaattta atactgaaaa tggtctagta acattagaag
    10621 acagtaaaaa agctcttaaa aaagggttaa ttgatagcta tgctcaatta cttgctttag
    10681 aagatacaat tcagattact aaaaaacaac ttgatttatc agaaaaacaa ttaaaaaata
    10741 ctaaattaag atatgattta ggattaatta ctctaactga ttataaaaaa caagtggtaa
    10801 gtaatgaaga tgctaaaaat agctatgaca ctcttattgt gaattataac tcactaaaaa
    10861 atggtataga aaaaccttgg atacttaata ctggaaaata attctggtaa atagaaagat
    10921 tactttaaca tacgtttgat taaaaaatag ttatgcacac tcgttgcttt agtcatggaa
    10981 gattcagaag gcaaataata gaaatagatt agtaaaaata tatttactta taaaactgta
    11041 tacttttata gaggctatct caaaatagag ataagcctct tttttattgt ttaaattata
    11101 aaaatatatt tgattccata caaaaagagt gccttctgaa ctaaaaagtt cattttgaga
    11161 caccctcaaa agcttaactc taaatttaat tattttttat caaatgtttc atctatttta
    11221 catctcacca tgttaacaaa ttcagaaata ttatatcctc taagtttgca tccacattta
    11281 ggacaataat ccagtttcct agataccaaa gccctacaac taggttctgg acatcttatt
    11341 tttagactct catctgctac tttaaatcca catcgtgggc atatactacc tggacgtgat
    11401 gatacttcct ttccacattt aggacacttt gtcaacttta tcccctccag taaactcaat
    11461 ttaattgata gttgaaattt ctctctacaa taatatatgc aatataatta aatacgtttc
    11521 acttacaact atataagtta aatttttata ataaaaatcc cctatattca atttacaaat
    11581 acttaatttg atacattgaa caatagggga ttttattttt atttagttac atattttgca
    11641 gtctattatt atctaggatt ttttatagat gcttgagctg ctgcaagtct agcaattggc
    11701 actctaaatg gtgaacaaga tacatagtta agtcctacac tataacagaa ctctactgaa
    11761 gatggttctc ctccatgctc tccacatatt cctagtttta attctggttt aacttctcta
    11821 cctaatttag ctcccatctt aactaactta ccaacaccat tttggtctag tacttggaat
    11881 gggtcttttt ctaatatttc ttcatctaca tattgaccta agaatttacc agcatcatct
    11941 cttgaatatc caaatgccat ttgagttaag tcattagtac caaaactgaa gaagtctgct
    12001 tcttgtgcta tttcatcagc agttaaacaa gctctaggta tttctatcat agtacctaca
    12061 gtataaggaa cttctatacc ttcttctttt attatagcgt caacagtttc tactatcatt
    12121 tttcttatta tttttaactc atttacttct ccaactaatg gaaccattat ctctggagaa
    12181 actttaacac ctgctttgat tgcttctata gcaccttgta ttatagcttt agattgcatt
    12241 acacatattt caggataagt tattgcaagt ctacaacctc tgtgtccaag cattgggtta
    12301 aactcatcta aatcaactat tctcttctta atatcactta cttttattcc catagatttt
    12361 gaaagttctt ctatagtctc atcatcatga ggcaaaaatt catgtagtgg tgggtctagt
    12421 aatcttatat taactggttt tccatccata actttaaata actctacaaa atcctctctt
    12481 tgcattggta atattttttc aagagctttt tctctttgtt ctactgtatt agataatatc
    12541 atttctctaa ctgctggcaa tctagcttca tcaaagaaca tatgctcagt tctacataga
    12601 cctatacctt ctgcaccaaa ctctatagct gcacgagcat ctctaggatt atctgcatta
    12661 gttctaacca tcatacattt gtgtttgtct acccagttca ttaatttttc aaagtttcca
    12721 gttaaagata cttctgtttt cttaacatct cctaggtaca catttcctgt agaaccatct
    12781 atagaaatgt attcaccttc ttttataact acatcatcaa gtgctcttat ttctttatta
    12841 aactcatcaa cttttatttc tccacatcca gcaacacaac atttacccat acctctagca
    12901 acaactgctg catgtgatgt cattccacct ctagctgtaa ggattccttc tgctttaacc
    12961 attccttcta tatcttctgg agatgtctct agtctaacta aaactacttt ttctcctttt
    13021 tcatttgctt ttactacatc atcagcattg aaataaactt taccacttgc tgcacctggt
    13081 gatgctggta aaccttttgc tataacctta gcttctttta atgccttatc ttcaaatttt
    13141 ggatgtaata attggtctaa ttgattaggc tcaattctca tgatagcttc tttttcatca
    13201 attattccag cttcaactaa atcaaccgct acatttattg ctgctgctgc tgttctctta
    13261 ccatttctag tttgtagtat atataatctt tcattttcta tagtaaactc tatatcttgc
    13321 atatctttat aatgaccttc aagtatatga gtaattttta caaattcatc gaatacagct
    13381 ggcattacat ctgcaagagt tgatatattt tgaggagttc ttatacctgc aacaacgtct
    13441 tcaccttgtg cattcattaa aaattcacca aataatttat tttctcctgt agctggattt
    13501 ctagtaaatg caacacctgt accactagtt tctcccatat taccaaatac cattgattga
    13561 atatttactg ctgttcctaa gttatgagct atatcattca atttacggta tacgattgca
    13621 cgaggattat tccatgatct aaatacagcc tctattgcaa gcattaattg ctcttttggg
    13681 tcttgtggga aatcattttt tatttctttt ttataaattg ctttaaattc ttttactatt
    13741 tcttttaaat catcagttgt aagttctgta tcaactgtgt atccctttgc ttcttttact
    13801 ctgtctaata cgttttcaaa tttatatttt ggaacttcca tagcaacatc agaaaacatt
    13861 tgtatgaatc ttctgtaact atcatatgca aatctttcat tttgtgtagc ctctgctaag
    13921 ccaacaacac tattgtcatt aagacctagg ttaagaattg tatccatcat tcctggcata
    13981 gagaatactg caccagaacg aactgatact aataatggat tcttattgca tcctaatgtt
    14041 ttatttaagt ctttttctaa agtagctaaa tgctcttcta tttcttttat tatctctgct
    14101 cttatacttt cattgttaac ataataatca ttacatgctt ctgttgttat agtgaatcca
    14161 ggagggacag gtaagcctat cttagtcatt tctgctaaat tggcaccttt acctcctagt
    14221 aaagatttca tgtctttgct tccttcacca aaactataaa catacttagt ttccattgtt
    14281 aaatccccca ttaatctttt tattttaatt tatatcattt ttattaatag acattattaa
    14341 atttctattt ctttgtatat ctttagacca ttttctttca ttatgtctaa aattatacct
    14401 gctgtttctt ctattgcctt atttgaaacg tttattactg ggcatccaat tcttttcatt
    14461 atctcttctg aataatctaa ctcctgaagt attctttcta aattagcgta gtttgcttta
    14521 ctggacaatc ctaaagcttt taatctttgg gttcttatct cattcagctt ttcaggtgaa
    14581 ttagtaagac ctattatttt tttagtatct atctcaaaca cttctttagg aattggtatt
    14641 tctggaacta atggaacatt agctactttt atatttttat tagctaaata catactcaaa
    14701 ggagttttag atgttcttga tattcccact aaaattatgt ctgcttgaag aacacctcta
    14761 gggtcttttc catcatcata tttcactgca aattctatag cttcaactct cttaaagtaa
    14821 gattcatcta attttctaat tataccagct tctcttttag gttttcttcc tgttctcttg
    14881 cttatttctc ttagtatatc tgtcattaaa tctatacaac taagaccttc tctttcgcaa
    14941 tatctttcaa caatactgca taattcttca tcaactaatg tatatacaat taaagcgttt
    15001 tcagcttttg cattctccaa agtttcaagt agtactcctt tattaatcat gtatggaaat
    15061 ctttttattt cataagtttc attcacataa aactgagaca tacatgcctt tgcaacttgt
    15121 tgtgcagtct cccctactga atctgatact gcatatataa ttaggttttt caccagcata
    15181 cctccttaat tgtcaactat ttctaagaat agcttagtta tgttggtttt tgatattctc
    15241 ccaacaactc tcatatgatt tttgtcttct cccttatatt caacaatcgg aatcgaatct
    15301 acttcatgtt ctattatttt tcttgaagct aataaaacac ttgctccttt agttaaagtg
    15361 actacatttg gagttcttgt cattatcata cctattggca ttttatttat atcagaacct
    15421 cctatagttg cttttagcaa gtcttttctg gaaacaactc cacataactc ttcattctca
    15481 tctataataa ctatactccc tacatcagat aaaaacatag tgactattac atcatatata
    15541 ctttcatcct tcttagctag tacaggcatg ctcattatat cctctactgt tttttctttt
    15601 acacttttac caattaaatt tatttcacta actcctgaat aaaaatatcc aacttttggt
    15661 cttgcgtcta atattcctgt cattgttaat atagctaaat cagatctaag tgtagcacga
    15721 gtcacattca agctggaggc aatactttca ctcgttattg gttcattttc cttaactata
    15781 tctataattt ttagttgtct ttcattaagc tgaataataa tcaccttctt tcattgtgct
    15841 atacttttta tcttttcgca tcttatatag tatattatat aactatatat accattctgt
    15901 aaacagattt tttattgaat acgatatatt ttttactaag ttctctcgct taaagatatt
    15961 tattatatat taatggggga tatttcttta attaatagaa ctatattagt attacagtta
    16021 atattataat acataattgg tcattttaat tcattttata ttaaaatttt taataatatt
    16081 gtttcaatgt gaatataaaa ttgcagaact aattcaaaat aatttttacg actacaaata
    16141 acctataata tacttttaaa gaaagtatcc taacaagaat atataaaaat ttaaaagggt
    16201 tgatttaaaa ataaccatca acccttttta ctaatatcta tttatattac catcaaatct
    16261 tacccaaata ttttttcttg caattgtctt aaatgatata aagtagtatc tttttctatc
    16321 tctaccatat cgtaagttat aacttcacct tttttaatgt cttttacaac tttagtcttt
    16381 ttacttatca aaccaatagg tacagcattc atagcctttg ctatatcgta tttttctata
    16441 gtaccatagc atgtatatgc tccatagcca tccataaact cacctttttt caaatctttc
    16501 ttagctatag tcataacttc tgctactagt ccagctttag gtactattgt agccttatgg
    16561 tctaaaactg ccatagctgc tgataaagga gtctctaaac tacataaatg atatggtcta
    16621 tataatatgt aattaggtcc atcacccata cttaaatatt ttagttcatc attaactgct
    16681 tttaatttat gggcaactac tacgaaaact ccaggtgcta taccatttac aaaatcaact
    16741 acaccataat tatctaatac tccaccttcg ctttttaatg catatttctt aggtacttca
    16801 ttaactgtag cttcaatacc atgaccacct cttacatcag gcacaaatcc agttgcatta
    16861 cacattaaag ccatttctac cattgtttta gttccttctt taaaagaagc tatcatatga
    16921 ggtgaagctc cttttctttc tgcttcttct ctaactgtat caggattaca atctaaatct
    16981 aatttattat ttttaccttt acctatcact ctaacttcaa accccattgc atctgcaaaa
    17041 tcaaataatt ccattactgc acctggctca tctcctgcag aacctgtaaa tattactcca
    17101 gcatcatctg ctaatttttt aagtattggt ccaacaacac aatcagtttc agcatttaac
    17161 ataactatat gttttttatt taaaatagag tttaatgcta tctctgcacc aattgcaata
    17221 cctccagttg catctataac tacatctatt gacttagttt tacaagccac aagaaaatca
    17281 ttacatgtca atacttttcc ttcttgtaat tttatttctg catccttttc atttgttaca
    17341 ttatctataa tttcttcatc tattcctgca tcagtaaaag ctttatgagc caactccaaa
    17401 tttatatcta caacaataga agcttcaata cctttcatat ttgccatttg gcttaccatt
    17461 ccatttccca tatgcccagc tcctataaga gctactttta tttttttacc ttcctcttcc
    17521 aattttgcaa gttttctgtt taaatctaac ataccaattc ctcctgttat aataatttta
    17581 ttttcaaatt aagaaatagt tattaaatct ccaatagtta tatctggatt tcctatttcc
    17641 acatgtattt ctcctggtaa atttacttca cattttccat caaatttgat tgtacaatgc
    17701 ccaatttctc taagagtctt ctgagcaata tcaccaactg aaactataca ataatctcta
    17761 ttccctatag taagtgtatc tcctatttca acatcacttt ttaacgttgc tattgaatga
    17821 attacagata tatcctttaa gtcgtcatca ttaatggttt catcatatat aataagacaa
    17881 ttgctttcat ccattaactc tttaactaaa ctgcctatcc cacttatctt aacttcatat
    17941 ttcatgacat tcctcctgat aatttatatt tatattgagt taattaaaag aaacatttat
    18001 tttttctttt ataaatttta tagcttgtac aatactctct tcatctttaa atttttgctc
    18061 tgcactatat atatctaatc cttctatttc ttcaatctct ttaaatttag ccattactgt
    18121 acgccctttt aaaatttctc caaactttat aaatccatct gaatctgaag atataatggc
    18181 tatacttcct ttagaaaaat agcttttctt tttgcctgta gacactatat cacccttttt
    18241 tttagctcta tttaaagttt taaaatacaa tttattctgc ttcattataa atatagtatt
    18301 taaaatataa gcaacaaata aaatcactaa taatttcata tttatacacc ttccaaaaat
    18361 cacattattt ttaaatctgt ataacaacta taaatgctgt acaatagtta tataaggttt
    18421 ttaagtaaca cctttttaaa ttctaaaaaa gttctacatt tacttatctt attcgttaat
    18481 tttacatctt ggcctatctt taaaacttct tcataaattt ttactaataa gtctgagtct
    18541 atcttattct cacatggaaa cattgtcata agaattattt ttatacttct atttgcatat
    18601 tctattggtt cttctaaaat tccaactgcc attaaaaact tatctgattt ttcatttaca
    18661 gaatgaggaa ataataaacc tttatcaaat actgtgggag atttttcttc tctattgact
    18721 atattttttc taaacttatc atcaatgcat cccaaatcca taagatggtc catcattttt
    18781 tctaatgaag caagtatagt cttttcattt aatatcataa atttatcttc atctaacaaa
    18841 ttatttatta gtaaatttgt agaattagta gtgtcaatat tcccttctct taggcacaat
    18901 actgttttta attgttctct tagtttgttt tcatcaaata ttgtatttat ttttaatact
    18961 attgtattta tatttgatgt gtctaaatca atagttgtaa aaactatatc gtattcatct
    19021 aagttaatat ttctcaaatt aaaacttgaa agagtatcaa ttttaggatt atttcctatc
    19081 agtttttcta ctcttatttt caatagtttt gctgttccta gacctgtact acatataatt
    19141 gctatttttt ttattgaata gaatctactg ctatttcttt ctaaatatcc actgaaatgg
    19201 attgctatat atccaatctc atcttctgaa acttctaagt tatacttttt ctctattact
    19261 tttcctgcta tttgtgctaa tttaaatgga agtatataat tttgcttaat ctcttctaac
    19321 aaaacatttt ttaactttat attaaataat agcctgttta aagtaaaact aagatgatat
    19381 cctagaccta ctcttaattc atcctcattt ataaaaatac ccatatcgac atatatttga
    19441 ttaaatatat tttccatcaa ctcatcaatg tttttactaa ttctactact atttaaagca
    19501 cattctgatg ctggtgcatt tccactaact aacggtatag ttaaataaat aatttcttca
    19561 tcatttaaag tacattcaaa cattcctgat attatatgtt ttatttccct agcaataaag
    19621 tattcatcat atgatttaag taaatcaaac tttacatcat aatcttttac tttcttttct
    19681 tcttttactc tatagactaa aactactatg tagttaataa cttctcttaa catttcatct
    19741 gtaacataaa aattattttt tttaaataaa gtcaatagtt tttcttctaa atttatgatt
    19801 tcttcttttt tgattccttt aaaatacttt gaattactga aatctttcct tgagttttta
    19861 tacaactgat ttaatataaa cagtctaata tcaagttcat ttccatttaa tttcatacct
    19921 gtattctgtt ttttaatcaa gtttaaatta tatgaagcca aaactttttc tacatactgg
    19981 aaatcattta ctaaagtagt tcttcctaca cacatctcat cagctaaact atcaagtgta
    20041 ataaatccat ctagttctat caagtaattt agtataaact ctactctatc ttcttttgaa
    20101 tttaatgaaa atacattttt tctattcata tcaataatct tattgagtat ctgctcatct
    20161 tttatttcta gtttatagcc ttgacccttt atatatttga ttactgctat atcattacct
    20221 aaatctttat tcaattgttt tatatacgtc cttacacttc tagttgtgac attcaattca
    20281 tttgctattg agttaatact cacaaactct tttttactac acataatcaa tatcttaaat
    20341 atcttgcggt caatagaagg aattttctca gttacactca ttttgtatct cctccttgat
    20401 ttcattctag tacaaatttg aaaccaaatt aatacataaa atttcacttt aataaaggaa
    20461 aatttagtat taatctaact cgataattac agctaattaa tagtataaaa gctagtcttt
    20521 cattaacaaa aaatcttgac tagcttaaat ttatatttac aattttatta attaattcca
    20581 agccttatat tgacattaaa tattatctca atgcaaatac tgcaactcca tatgcaataa
    20641 taacagctat tggaccagtt attaaacgag agtaaaataa agctggaaca ccatactcta
    20701 cagtttctgg ttctgcttct cccaaactta atcctactgg tacaaaatca catccagctt
    20761 gctcatttat tgcaaataaa gctggaagtg ctaaatatgc tggtattgca ccaagaccaa
    20821 tttgtgtacc tacaagagtc cctactactt gagctataac tgcaccaggt cctagtattg
    20881 gtgataagaa tggaagtgtg caaattactg atataatcaa taatccacca atattacctg
    20941 caagtggaga tataactctt gcaatccagt ctcccagtcc agatgctaaa ataattccca
    21001 taagcatact tacaaatgcc ataaatggta ttacgttatt cattaccatt tggatagtat
    21061 ctcgacctgc atcataaaat tttgatacta cttgccctgc cccttgacca atagaaagta
    21121 ttatgttctt tttagcatat tcaccttgtg cttttgactt aacctcatca taattatcag
    21181 gctttctaat agaactctta ttttcgcttt tattttcttg agatttttgt ggcatatctt
    21241 ccccatctac aacacttata cagttaggat taacatctga tacataatat tcttctgtta
    21301 taaattttgc taaaggacct gtttttccaa ctggatttac atttattgta ggtatttttt
    21361 tctttggata aactccacat ctagcagttc caccacaatc aataataact actgctactt
    21421 cttcatcaga aactccagtt ttaaatccat ctacaatttc acaacccagt agttctttta
    21481 tttttaatgt tacttcatgg ataccgccag cagtcattga tagtatctta tttctattcc
    21541 cttctttttt tatatacaaa ggacctcccc agcctgaagt tcccttttct atttttaata
    21601 ttttattctc ctccatttta tctacctcct aagccttatt tgttgctcta ttttttcttg
    21661 ttagaaaagc atacattttt tctgttacta tacctcttat aaaaattaca attagaccaa
    21721 ctataaaata ccacaatgcc aatgtagtag tttctttacc taaagtagtc aaacctgcag
    21781 atattcccaa ccatacaaaa agttctcctg catttgcatg tggaaaaaga cctgtaattg
    21841 gatgtacaaa tgaaactgct gcatcataaa atcctgcttt gtgctcttct tttaaaaatc
    21901 taccaaatgt atagcacata ggatttccca agaaaaatac tgatactaat ggaagtagaa
    21961 tatatcttgt aaaagagttc tttcctagct tagaagccca attattaact ctttcctcac
    22021 caattatctt aatcaaagag ttaatagcta ccattaatac aattagcgtt ggaagagtac
    22081 ctgaaacaag acctataaat tgttctcccc ctttctgaaa caaaccgata aaccactctg
    22141 cacctttact tagacctgta ataacgtttt ccataaaatt ataacctccc tataatatct
    22201 ttaaattttt aattttactg cttaccataa attttacaaa ttacatcttt tttctgtact
    22261 atatgctaat attgtaaatg tttttttatt aatatcattt taatataata tttttgataa
    22321 ataaatacat cttttttcaa ttttataaag gaaaaaattg tactaat
//
LOCUS       DAEPXW010000064        22286 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.065, whole genome shotgun sequence.
ACCESSION   DAEPXW010000064 DAEPXW010000000
VERSION     DAEPXW010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22286
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.065"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            445..1515
                     /locus_tag="KRM55_002439"
     CDS             445..1515
                     /locus_tag="KRM55_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594675.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
     gene            1499..2368
                     /locus_tag="KRM55_002440"
     CDS             1499..2368
                     /locus_tag="KRM55_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH1594676.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            2412..3272
                     /locus_tag="KRM55_002441"
     CDS             2412..3272
                     /locus_tag="KRM55_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH1594677.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            3303..4607
                     /locus_tag="KRM55_002442"
     CDS             3303..4607
                     /locus_tag="KRM55_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1594678.1"
                     /translation="MKLKRKLATGLAITLLLCSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            4670..5932
                     /locus_tag="KRM55_002443"
     CDS             4670..5932
                     /locus_tag="KRM55_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBH1594679.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            6119..8089
                     /gene="uvrB"
                     /locus_tag="KRM55_002444"
     CDS             6119..8089
                     /gene="uvrB"
                     /locus_tag="KRM55_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBH1594680.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            8108..10933
                     /gene="uvrA"
                     /locus_tag="KRM55_002445"
     CDS             8108..10933
                     /gene="uvrA"
                     /locus_tag="KRM55_002445"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1594681.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            11192..13009
                     /gene="uvrC"
                     /locus_tag="KRM55_002446"
     CDS             11192..13009
                     /gene="uvrC"
                     /locus_tag="KRM55_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBH1594682.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            13009..13938
                     /locus_tag="KRM55_002447"
     CDS             13009..13938
                     /locus_tag="KRM55_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBH1594683.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            14150..15946
                     /locus_tag="KRM55_002448"
     CDS             14150..15946
                     /locus_tag="KRM55_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBH1594684.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENIILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(16090..17871)
                     /locus_tag="KRM55_002449"
     CDS             complement(16090..17871)
                     /locus_tag="KRM55_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH1594685.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(17894..19780)
                     /locus_tag="KRM55_002450"
     CDS             complement(17894..19780)
                     /locus_tag="KRM55_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBH1594686.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            complement(19797..20294)
                     /locus_tag="KRM55_002451"
     CDS             complement(19797..20294)
                     /locus_tag="KRM55_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBH1594687.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            complement(20612..22093)
                     /gene="cls"
                     /locus_tag="KRM55_002452"
     CDS             complement(20612..22093)
                     /gene="cls"
                     /locus_tag="KRM55_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH1594688.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
BASE COUNT         8590 a         2980 c         3705 g         7011 t
ORIGIN      
        1 gggtaaattt ataaaaatta aaaaattttt attttttatg tttaaacctt gtaaatttgg
       61 gacataatat aattgtaaaa cttaatatag caaaaataaa ttactcaatc tcccccactt
      121 aaagacctct atcccccata gaggtctttt ttactttcaa accaaattat ataaaaaata
      181 aatagtttta tatgactctt cataaattaa aattacattg tgatagcaaa ccatgaatat
      241 gaaaaatata gaaaattata gctaacataa gctgtatatc atcttaactt cagtatattt
      301 aacaaaaaat gtttataatt taacctttat tttaataagt ttaccatata ttcactttgt
      361 cttaatatat cctttacaaa ttaagagtat tattaatcta taagtaaatc gtagaattaa
      421 attaaatatt ttgggaggat aaaaatggca gatataagac tagaaaatgt aacaaaatct
      481 tataataaaa aaaatacagt tatagaaaat ttaaatctta ctatagaaga tggttctttt
      541 acagtattgg taggcccaag tggatgtggt aaatctacta cgttaagaat gattgcaggt
      601 cttgaagata taacttcagg taggttgaag attgaagaaa atgatgttac aaaaacggat
      661 gctagtaaaa gggatatagc tatggtattt caaaattatg cattatatcc acatatgact
      721 gttagagaaa acatagaatt tggtcttaaa aacaaaaaag tagaaaaaga aaaaagagaa
      781 aaacttataa cagaagttat tgatgtagta ggattgagag aatatttaaa tgtgaaacca
      841 ggcaacttat ctggaggtca aagacaaaga gtggcacttg ctagagctat ggttaaaaat
      901 ccaaaggtat ttttaatgga tgaaccattg tcaaatttag atgctaaatt aagaaatcaa
      961 atgagaacag aattaataca attacatcaa aaactaaagt ctacatttgt ttatgtaact
     1021 catgaccagg ttgaggcaat gtcaatggca gataagatag ttataatgaa caaaggaaag
     1081 ataatgcaaa taggttctcc aaagaagata tatcaaaatc ctaaaaattt atttgtagct
     1141 caatttatag ggagtccttg tatgaacata ctagatataa aaaatgatat taaatttgga
     1201 ttcagaccag aaaaagcaac actagagagt ataaacatag atgggaaaaa tgatgatgta
     1261 tttagtctat ttggaaaagt tgtaactaaa gaagtgttgg gaaatgaaac tatatattgt
     1321 ttatctgttc ttaatagaga gataagagtc aaaacggaaa atgatatatt tgatattgga
     1381 agaactttaa gaataagtgt attagaaaaa gatttatatt attttgataa aaatggagaa
     1441 agaatagaag atgtaaaagt atgtaaaagt atgtattcta aaatcaaagg agatatttat
     1501 gaaaaagcaa tttaataaag catatttata tataacacct gctattatag gaactttatt
     1561 gtttatagtc tatccaataa ttaagacgat atctctaagc ttcaaatctg gtagtcttct
     1621 tagttcaacc tttgaaaatg taggcttaaa caattataca gaacttttaa agaatccaga
     1681 gtttatacaa actataacaa acactgcaat ttatactttt tttatggtga ctatatctat
     1741 atcactagcc atagtacttg ctgtttggct aaataaaaat tctataatac acaatttaac
     1801 gcaaagtata atctttacac cacatgtaat ttcactagta tctgtagctg tattgtggct
     1861 ttggattatg gagccacaat atggcttttt aaactggata ctatcgacat tacatttacc
     1921 aacatcaaag tggctttcaa gtgaaagttc agctttaatg tcactaattc taataggaat
     1981 atggaagact cttggatata atatcttaat agtgttatca ggtcttaaat ccataccaaa
     2041 ctatatatat gaagcatcta aattagataa tgcaaacaaa ataacgaatt tctttaaagt
     2101 gacattgcca ctattatcac caacaatatt ttttcttatg ataacaacaa caactgcatc
     2161 ttttcaagta tttgatgaga taagtataat gacacaaggt gggccagtgg gttcaactaa
     2221 catgttatct tattatatat atgagtctgg atttatatac tatgacatag ggcaagcgag
     2281 tgcagcgagt atgtttttgt tagctatagt tatgattgct acatatgcta actttagact
     2341 cttatcaaag aaagttcatt atcaataaag aaaaagtaga tattataagg tttatccaaa
     2401 aggaggagac aatggatatt atacaaccta tcaaaaaaga caaagttgat ataaaaaaaa
     2461 tagcatcaaa atcaatagaa atattaattc tattactttt atctgcaata tttatattcc
     2521 cttttatatg gatgctatct acatccttta aaaatccaca agaaatgatg caattaccgc
     2581 ccactattat accaaatgat atagtgttag aaaattatag tacagcatgg cattcaggtc
     2641 cattttttag atatttgcta aacagtgtat ttgtaacagg aagtgtttta attgtacaat
     2701 ttttagttat ggttccagca gcatatgcat tttctaagat taaatttaaa ggtgaaaaaa
     2761 tgctatttgg gcttttgctt gtaggactta tgattccacc acaagtaact tttctaccag
     2821 tctatatgat gatgagtaag tttggattta taaatactta tgttccactt ataattccat
     2881 ttatgacatc ttcatttggg atatttctgc ttagacagaa ttttatgcag atttcagatg
     2941 aaattattga agcagctaaa ctagataatg cttctgactt aaaaataatg tttagaataa
     3001 tggttcctat ggcaaaacca gcagtaataa catttatatt atttaatttt atataccatt
     3061 ggaataatta tttctggccc ttagtaatga caaatacaga tgcaataaga actttaccaa
     3121 taggagttgc gctccttaaa tcttcagaag gaattactgc atggaatgta ataatggcag
     3181 gaaatataat tctaatttta ccaataattc ttgtttatat atttgcgaat aaaaaagtaa
     3241 aagaagcttt tatgtattca ggaataaaat aaaaaattaa agactaaatt tggaggatga
     3301 aaatgaagct taaaagaaaa ttagcaacag gattagcaat aacattatta ttatgttctt
     3361 tagttgggtg ttcaaattct aatgatgcaa atgcatctaa aggagaaaag actgatagca
     3421 atattacgaa gatagatttc tgggctcctt taggtggaac taatggagaa actgctcaaa
     3481 aaatggttga ccaatttaat agtgaacata aggatgtaca agtaaatatg ttaaaacaga
     3541 aagattacta tgaaaatgca acaaaactac aggcagcctt aacatctaaa gaccaaccag
     3601 atgtaacatt attagaaata actcaaacag gtacattcgc atcagcaggt gctttagtag
     3661 atatgagtaa atattttgat aaaacatatc aagaaagatt cttttctggt cttttaacaa
     3721 attcatatta tgaggataag tttgttggta tgccatttaa tagaagtaca ccaatattat
     3781 acataaataa agatatggca actaaagcag gtcttgaccc ttcaggtcca aaatcatggg
     3841 aagagcttaa ggattatgct agtaaaatga caaataaatc agaagatact tatggttttg
     3901 aaacaccaat agatatttgg ttctatgaag ctatggtaat gcaaagtgga ggagaaataa
     3961 ctaatggtaa aaaagtagca tttaataatg aggcaggaca agcaccagtt aagttctggc
     4021 aagatatgat gaaagctgga ataatgaaaa tgcctcctgg agaagattat aatgcctggg
     4081 acgtagcaaa acaagatttt gtaaatggta aagtaggtat gatatttaca tcaacagcag
     4141 atttagcagg acttatgcaa caaacagaag gtaagtttga aatatcaaca gcattcttac
     4201 caaaaaatca aaaatacgca actcctacag gtggagctaa tctagttatg cttgaaggtg
     4261 gaacagataa agaaaaagaa gcaagtgcag aatttataga atggatgaca caaacagata
     4321 aaatcgttca gtttagttca tcaacaggat acttaccaac aactgaagat gcaacaaact
     4381 cagaaaagtt acaaacatta tataaagaaa aacctcaata taaggttgca actgaccaat
     4441 tacaatatgc tgttgcactt ccaatgttaa atggatacaa ggaagcaact gataagctaa
     4501 tggatgagat taaaaagggg cttactgatt taaatgcaaa tccaaaagat gtagtaagca
     4561 aaggaacttc tgcaatgcaa gcagtaatag ataaaacaaa taaataatta tatagacttg
     4621 taagttgatt aaaagtattc aataatatat aaatgaagag gtaatgtaaa tgacaaaggt
     4681 tatagtatta tcagtagatt ctttatttga aaaagacttg gaatttgtaa aaaatctacc
     4741 aaactttaaa tctatactag aaaattgctc catagtaaaa aatataaatt gtgtttatcc
     4801 cactctgaca tatccgtgtc atactagtat ggttacagga gtatatccta aaaaacatgg
     4861 tatatatcat aatgaaaaat ttgacccaaa taaagaaaat aaagactggt actggtactc
     4921 aaaggacata aaagcaaaaa ctattataga tgtagcaaaa gaaaataatc taactacctc
     4981 tagtgtatta tggcctgtaa tgggagcaaa tccaaatata gattataata ttgcagaaat
     5041 atgggctcct agtagagaag atgacccaag agaaactttt gaacgaagtt ccagtaaggt
     5101 tataatggac ggtatttaca atagacattg tcattatatc gattggaaat tagaacccaa
     5161 catggattta tttggagtaa actgttcagt agatataata aaggaatata aaccagattt
     5221 aatgctaata catttagcta cattggacca tacacgacac aattatggct tatttaatga
     5281 cgaagtagat aaagcattaa aaatgaatga taaatggcta ggagatatta ttcaggctac
     5341 aaaggatgca ggtacataca aagatacaaa ttttataata cttggggacc atggtcatct
     5401 tagagttgat aaagttataa atccaaatgt cttgcttaaa tcaaatggat ttataaaagt
     5461 tgaaaatgga gaagttaagg attttgatgc ctatgtaaat tcttctggaa tatcagctca
     5521 aataatagta aataacttag ataggttaac agagttaaga gaactgcttg aagaatttaa
     5581 agaagaatta ttcatagaga atatttttac caaagaggaa gcatctaacc ttggtcttga
     5641 aggtgatttt gaaatggtaa ttgaaggtct tgaaggaatt tcatttggaa atgatttcga
     5701 aggaagtatt ataaaagatt cagatataaa agattacaag tttgctgttg cgacacatgg
     5761 tcatttacct actaaaggta atagacctcc atttatagct tttggaccaa atattaaagg
     5821 tggtgtggtt atagaagaag gagacctgag agcacatgca gcaactatat taaaaatgtt
     5881 taatttaaaa ttagatggag ttgaaaaaga agcatttgat tttattatgt aagttgaata
     5941 aagtatttat tttccatgaa ttatagactt ctattgcaaa gatagaagtc tttttttatg
     6001 ttttagattt aagtaaaatt taaatgggta aaatatttaa aataacttaa acaattttat
     6061 aaaggtatga tataataata catgtcagga actaatgttc gaaaaaagga gtgatactat
     6121 ggattttaaa ataaaatcag acttcaaacc tacaggtgac caaccagaag ctattaaatc
     6181 aatagtggat tctataaata gaaatgagaa attttcgaca ttattaggtg taacgggttc
     6241 aggaaaaaca ttcacaatgg caaatatcat tcaacaagtt aagaaaccta ccctaataat
     6301 ggctcataat aaaactctag cagcacaact ttacagtgag tttaaagaat ttttcccaga
     6361 caatgcagtt gaatactttg taagttacta tgattattat caaccagaag catatgtagc
     6421 tcacagtgac acttatatag aaaaagatgc aagcataaat gatgaaatag ataaacttcg
     6481 acattctgct acagcatcta ttttagagag aagagatact ataataatat catctgtatc
     6541 ttgtatatat ggacttggtg acccaaaaga ctataaagaa cttatgttat ctataagacc
     6601 aggtatgcaa agagacagag atgatgtaat aaaaaggtta atagagatac aatacgaaag
     6661 aaatgacata aactttacac gaggtacctt tagagttaga ggagatatac tagaaatatt
     6721 cccagctagt aatgatgaaa aagcaataag aatagaattt tttggtgatg aggtagatag
     6781 aataacagaa attgattatg taacagggaa gattgttggt actagaaatc atgttgttat
     6841 attcccagca tctcactatg taacaacgcc agaaagaatt gaaaaggcaa ttgtagaaat
     6901 agaaaacgag cttcaagaac aaattaaatt tttcaaggaa aatgataggc tattagaagc
     6961 acaaagaatt gaacaaagaa ctaagtatga tatagaaatg ttaaaggaaa taggattttg
     7021 tcaggggata gagaactatt ctagacatat tacaggaagg tcagaaggag aaagaccata
     7081 tactttaatg gatttcttcc cagatgatta tttgataatt gtagatgagg cacatgtcac
     7141 tataccacaa gtaagaggta tgtatgcagg agacaggtct agaaaaacat cacttataga
     7201 gaatggtttt agattacctt ctgcacttga caatagacca ttaaattttc aagaatttga
     7261 aggaaatata aatcaaatgt tgtttgtaag tgctacacca gggccttatg aaattcaaca
     7321 ctcagagaca atagcagaac agataataag accaactggc cttttagacc caattgtaga
     7381 agtaagacct ataaataatc aaatagatga tttggtagga gaaataacta aaactataga
     7441 aaaaaatgaa agagtgctta taaccacttt aactaaaaaa atgagtgagg acttgactaa
     7501 ctatcttaaa gaaataggga taaaagttaa atatttacac tcagatatag ttacattaga
     7561 aagaacagaa ataataagag atttaagatt agggaagttt gatgtccttg taggaataaa
     7621 cttacttaga gaaggattgg atataccaga agtttcactt atagcaattt tagatgcaga
     7681 caaagaaggt ttcttacgtt ccgaaacagc tttaatacag actattggac gtgcagctag
     7741 aaatgaaaat ggaagagtaa ttatgtatgc agacaggata actgactcaa tgcaaaatgc
     7801 tattgatgaa acaaagagaa gaagagatat acaaaattta tataatgaag agcacaatat
     7861 cattcctaaa actatacaga aaaatataag agatagtata gaagctacta aggttgcaga
     7921 ggaagaagtt gtatatggaa tatctgatac agatgataaa gacgaaataa gagctaatat
     7981 agataaatta aaatcagaga tgatggaagc tgctcaaaac ttacaatttg aaagagcagc
     8041 agaacttaga gataaagtga aacaattaga agaaaaattg gaaaaataga aaggtaaaaa
     8101 caacattatg gaagataaaa ttataataag aggagcaaaa gaacataatt taaaaaatat
     8161 agatttagaa ttaccaagag ataaatttat tgtttttaca ggtttgtcag ggtctgggaa
     8221 gtcttctttg gcatttgata caatatatgc agaaggacag agaagatatg tagaaagtct
     8281 atctgcttat gcaagacaat ttttaggtca gatggaaaag ccaaatgtag aatatataga
     8341 gggtttatca ccagctatct caattgacca gaagactacc tcaaaaaacc cacgttctac
     8401 ggttggaaca gtaacagaaa tatatgatta tttgagacta ttatttgcaa gagtaggaga
     8461 tgtgtattgc cctacatgtg gtgaaaaaat aagtcagatg actattcaag aaatagttga
     8521 taaaatgcta gattttccag atagaacgaa attacaaatt ctttcaccaa ttgttagagg
     8581 acaaaaaggt acacataaaa aagtctttga taatatcaaa aaagaaggat ttgtaagagt
     8641 tagagttaat ggtgaaaact atgaagttag tgatgatata atcttaaata aaaatcaaaa
     8701 acataatata gaagttgtag tggacagaat agtaattaaa gatggaatag aatcaagact
     8761 agcagattca attgaaactg cagttaagct atctgatggt cttgtaatag cccaaataat
     8821 agatggagaa gaaattcttt tttcaactaa atttgcatgc ccagaacatg gaattggcat
     8881 agaagaatta tctccaagaa tgttttcatt taatgctccc tttggtgctt gtgatgtttg
     8941 taatggtctt ggggaaagta aagaagttga cccagaatta gtagtaccaa acaaagattt
     9001 atcaataaaa caaggtgcag tggcagcatg gggttcaaca ggtgttaatg atgacactta
     9061 ttacagtaaa atgataaaaa gtttagcaga gcattttaat gtatctttga caacaccgtt
     9121 taaagattta ccagatgatt ttgtggagga attactttat ggtaaagata atataattgt
     9181 agagtttact tatgagtcaa aatttggagg aactagaaat tataaatcat actttgaagg
     9241 tgtaatagta aacttagaga gaagatatag agaaactaat tcagattaca tgagagataa
     9301 gattgaagaa tacatggcag agagaccatg tccaaagtgt aaagggatga gacttaaaaa
     9361 ggaagtttta tctgttttag ttgatggaaa aaatataatg gaagttacaa acttatctgt
     9421 aaatgaattg attgacttta tggaaaatat aaatcttaca gaaaaacaga gatttatagc
     9481 tcatgagatt ataaaagaga taaaaggaag agctatgttc ttaagagatg taggtcttga
     9541 ttatttaaat ttatcaagaa aagctggaac tttatcagga ggagaagcgc aacgtataag
     9601 attagctact caaataggtt ctgcattggt tggagtttta tatgtacttg atgagccaag
     9661 tatagggctt caccaaagag ataatgatag gcttataact actcttagac atctaacaga
     9721 tttaggaaat accttaatcg ttgtagagca tgatgaagac acaatgagag aagctgatta
     9781 tgttatagac attggtccag gtgcaggtat acatggtggt gaaatagttg cacagggtac
     9841 tttagatgaa ataattgaaa atgagaactc aataacgggt caatatttaa gtggtaaaaa
     9901 acaaatattg cttcctgaga ctactagaga aggaaatgga agttttatag aaatagttaa
     9961 agcatcagaa aataatctga aaaatattga tgtaaagttc ccattaggta agtttacatg
    10021 cataacaggt gtttcaggtt ctggaaaaag tacattaata aacgatatac tttacaaagg
    10081 tgttgcaagt aaagtgaata gacttaagca aagagctggt aagcataagg agataaaagg
    10141 aattgaaagt atagataaag ttataaatat agaccaaagt cctattggaa gaacacctcg
    10201 ttcaaatcct gctacttata caggtgtatt tgattttata agagatattt ttgcatctac
    10261 taatgaagct aaagcaagag gttataaaaa aggtagattt agttttaatg taaaaggtgg
    10321 tagatgtgaa gcttgtaagg gtgatggaat aataaaaata gaaatgcatt tcttaccaga
    10381 tgtatatgtt ccttgtgaaa tttgtaaagg tgaaagatac aatagagaaa cattgcaagt
    10441 aaaatacaaa gataaaacta tatctgatat attagatatg aatgtggaag aagctgttga
    10501 gtttttcgaa aatataccaa atataaaaag aaaattagaa actttaatgg atgtaggact
    10561 ttcatatatt aaattaggac agccttcaac tcaattatca ggaggagaag cacaacgtat
    10621 aaaattagct gctgaactta gtaaaagacc aacaggaaag actttgtata tattagatga
    10681 acctactact ggacttcata tggcagatgt agacaagcta atccaagtat tacaaagact
    10741 agcagataca ggaaatacaa ttatagtcat agaacataat ttagatgtta taaagacttg
    10801 tgattatgta atagacttag gaccagaagg cggagataag ggtggaacta tagttgcaac
    10861 tggaacacca aaagaagtat ctaaagttga tggttcttat acaggtcaat tcttaaagaa
    10921 atatttttct taagttatat aaattgtgaa aaattttaga gcagatatac gataaactgt
    10981 tttgttataa gtaaattagt caaatataag ttgtaaatag taatacaaag taaagtccat
    11041 attactcttc atggttaaca ttgttttcaa atcaattata gaagggaata tgggctttaa
    11101 cttgtttaaa gcactggaaa ttgtataact ttttaaaatt catattttag ggtataattt
    11161 tagtataaaa tttaatgttt tggagggcga gatgtttgat atacaagagc atttaaaaaa
    11221 attaccttct gagcccggag tatatttaat gaaagacaaa tacgaccata taatatatgt
    11281 gggaaaagcc atatctctaa aaaatagggt aaggcagtat tttcaatctt caaaaaacca
    11341 tacatctaaa gtaaaatcta tggttaagaa tatatataag tttgagtata ttataacgga
    11401 ttcagagtta gaggcattaa tacttgaatg taatttaata aaaagataca gaccaaagta
    11461 taatgtagtg cttagagatg ataaaactta tccatatata aaagtaacta cgaatgaaga
    11521 ttatccaaga atcttaaaag ttagaagagt tcttaaagat aaggcaaagt attttgggcc
    11581 ctataccaat ataactgctg tgaatgatac cttggagctt ataagtagta cgtatccaat
    11641 aagaagctgt aaaatagata tagataaagc aataaagaat aagacaagac cttgtttaaa
    11701 tctacacata aataaatgtt taggaccttg tacaggaaat gtttctaaag aagagtatgg
    11761 aaaaatgata gaagagatta taatgtgttt atctggtaaa gaagaaaaat tgatggaact
    11821 tttaaaggaa aaaatgaatg agagttctat gaactttaga tttgaagagg ctgctgtata
    11881 tagggataag ataaagagcc ttgaagagat gatacagaaa caaaaaatag atgctactgt
    11941 aagtgactta aaccaagatg tggttgcaat ggcaagagct cataatgaag cttgtgtcca
    12001 ggtatttttt ataagaaatg gtaagattgt aggtagggaa cattttatat tagaaggggt
    12061 aatggatagt ccaagagctt ctatattaag ttcatttgta aaacaatttt ataatgaaca
    12121 agagtatata cctaaagaat taattataga agatgagata gaagatagtt ctatattaga
    12181 agaatggctg tcatctaaaa aggggcaaaa agtaacaata agagttcctc aaaagggaga
    12241 gaagaaaagc ttagttgaaa tggttaggaa aaatgctgta gaatatcttg aaaaattttc
    12301 tgatatgaat aaaagaaaat atgaaaaaag tattggagca ttggaagaat taaagcaaat
    12361 attaaatcta gaaaagttgc caataagaat agaggcttat gatatatcaa atatacaagg
    12421 tgtagattcg attggttcta tggtagtgta tacgaatgct aaaaaagata agaaggaata
    12481 taggagatat aaaataaaga cagttattgg acctaatgat tatgattcta tggctgaaat
    12541 tgtagataga agattaaaac atggaaattt acctgacttg atattgttgg atggtggaaa
    12601 aggacaagtt agtgcagtaa aaaaagtact agaactcaat gatgtagata tacctctttg
    12661 gggaatgtac aaagatgata agcatagaac taaaggattg atatgcaaag aaaaagaaat
    12721 agaactagat aaaacaacta atttatatag atttattgct agtatacaag aagaagttca
    12781 taattatgca ataacatatc atagaagtct aagaaataaa gctttgacaa aatctatctt
    12841 agatgatata caaggaatag gtgaaaaaag aaagaaatca ttattaaatc actttaaaga
    12901 tgtagatgct ataaaaaaag ctactatgga agaactttta gaagtagatg gaatgaataa
    12961 aagcattgca gataatgttt ataatttttt tagaaaggaa gaaaattaat ggaaactagc
    13021 aataaagtat caataagaga gataataaaa gagttgaagt taaaagtagt atacatgcct
    13081 gatgatgtag attattatgt ctactctcaa gatataaata gaccaggatt acagtttgca
    13141 ggatattttg attattttgc atatgaaaga atacaaatag ttggaaagac agaatataat
    13201 ttttttggat taatggatag tcatattcgg gaagaagtac tagatagatt tttctcatat
    13261 gaaataccag cgttaataat ttctagagac ttggaaatca agccagatgt aattgaaaag
    13321 gctaaaaaat ataaaagaat acttttgagc acaaatagaa ataccactag acttataaat
    13381 agactgtcaa actatttgga taataagtta gcaccacata caacaattca cggtgtgcta
    13441 gtagatattt atggtatagg tgtactgata aaaggtgaaa gtagtatagg aaagtcggaa
    13501 acagcattag aactgattca aaggggtaat agattagttg cagatgatgc tgtagaaata
    13561 agaaaattag atgaaagtat gcttgtgggt cagtcacctg aactaataag acattttctt
    13621 gagataagag gaataggaat aatagatgtt agaagtttat atggagtagg ggcaatcaaa
    13681 aattctaaaa tgatagattt agtagttcat ttagaagctt gggatgaaac taagtattat
    13741 gatagactag gactggataa agaatatgaa gaaatacttg gtgttaatgt agagaaatta
    13801 gttgtacctg ttaaacctgg aagaaatact gctatgatat tagaagtagc agcaatgaat
    13861 tttagacaaa gaggaatggg atacgatgca gctcaagaat ttactaaaaa attatcaaaa
    13921 ttaatcgata ctaagtagta ctgaataata gtggactaca catcatttaa ttaaatattg
    13981 attaggatta tgtcctacac cttataaatt aaaatcaagt tgtatatata atgtttatta
    14041 ataagatata ttatataagg ataatttaaa gtacagtgtt agattataat aatactagat
    14101 taattttata tttgagtttc attatataac aagaaagttg gaatttttta tgggaataga
    14161 atattttagt aaacttttag aaagtagtac tgaaaaagaa ttgctcttaa gtaaaaagtc
    14221 aaataacata agtacagcaa gattaatatc ttttttgata gtgatagcag ggcttgctat
    14281 tggattttat aataaaaata tagtaggtat ttttgttgga gttttatcaa taataatatt
    14341 tatagcactc ttagttattc atagtaaagt aaaagaagaa gaaacatatt ttaaaagtaa
    14401 gagcgaagta ttaaataagt atattaagag atttggagat ggttggaagg aatttaaaat
    14461 agatggtaaa gaatacttaa aagatgaaaa ttcgcaagca aaagatttag acttatttgg
    14521 aagagcatca ttgtatcaat atatctgtgt agctaataca tcttatggga aaaatttttt
    14581 agccaaatat ttgtggaatg aaaatccaga tgagaatata attttagaaa gacagagagc
    14641 tataaaagaa cttttatcaa aagatgattt ttctattcat attcaaacac tcagtaatat
    14701 aattggtaaa gagcaaaaaa acaattcaga tagtagtata gaatcgttta tagaatatgg
    14761 agaaaataag aatgtgtata taccaaaatg gatgcatatt tttacttggg gtttaccaac
    14821 tgcaacaatc ttatctttta tattttgtat gttaggattt ttacctgttt tacctgtttt
    14881 tttacttttt ataatccagt tagggtttag tggttttgga tatccaagac ttatgcaaac
    14941 tcttgctcca ttattttcat ttagtagaag tatacaagta tatgaaaaaa tgtttgaggt
    15001 tttagaaaaa gagacgtttg agagtgcata tttgaaagaa ttacaagata aactttctaa
    15061 gggaagtgga gtttcaagag gtgttaaaca attaaattca ataggaaatg ctgtaaacct
    15121 aaggtataat cagatactat atataattgc ctgtggtgtt ttgatgtgga actatcattg
    15181 tgcagaagct ttggagcgat ggaaaggtat atatggaaat caaattagag attggtttga
    15241 atctattgga gaatttgaag ctctaataag tttaacagtt gtttctcatg taaaggaaaa
    15301 tacatgtttt ccagtaataa aatatgaaga tactccaaga ttgaaagttg aagaggtata
    15361 ccacccatta atagcagaaa aaagtgtcat agcaaattcg atacaattaa attctcagac
    15421 ttgtattatc acaggttcaa atatgtctgg aaagacaaca tttttaagaa gtatcggtgt
    15481 aaacttagtg ctggcatatg caggtgctcc agtatgcgct aagagttttg atgcgacctg
    15541 tatggctata tttacttcta tgagaataca agatgatgta agtcaaggaa tatcaacttt
    15601 ctatgctgag attcttagaa taaaatcaat gattcaatat agtttaaaag aactgccaat
    15661 gttggttcta gtagatgaaa tttttaaggg aactaactct gctgatagaa ttattggagc
    15721 aagtgaggca gtaaagaaat tatcaaaacc ctgggttata agtatggtga caacacatga
    15781 ctttgagcta tgtgaccttt caggtagcgg agatgttgaa gttgtaaact atcatttctc
    15841 agagtactat gtagacgata aaattcattt tgactataag ataaaagatg gaagatgtaa
    15901 aactacaaat gcaaaacaac ttatgagaat ggcaggtatt ctttaattaa tagataggtt
    15961 aattaataaa taaataagtc tatttagaaa tataatttaa tttgtgaaat taataaggat
    16021 tgtcttaaat tacgtaaaag tattttaaga caatcctttt ttaagaataa attttatact
    16081 ttgttatgac tacttagctt cttcacaagc acattcttgt ggacactctc catagacaca
    16141 actcttatca aagtaatgag tatgaaggta tttatgagct acatcactat ttggttctcc
    16201 aaagaagtct ttataaatag cttgtaaatc aggattctca tgagatttac gaatagcctt
    16261 atttctatct atttcatata acgcatttgc acgtctatca actatttcag tattaccatg
    16321 gtgataaggt tgaccagcac ctccaacaca tccaccagga catgccataa cttctatgat
    16381 atggtattta cattctccac ttctgacctt atccataatc tttctagcgt ttttaagtgt
    16441 atttacaata catacattaa ctgtagttcc atcaacatct atacttgctt ccctaattcc
    16501 tttaagacct ctaacattag tgaagtttac attatctaaa gtcttattag ttatcttctc
    16561 atatgaagta cgtagggcag cttctaaaac tccaccactt gctccaaata tagatgcagc
    16621 acctgtagat tttcctagag gattatcaaa atcttggtct tgaagattag gtaaatcgat
    16681 tgcagcttct tttatcatct tagctaactc tctagtagtt atagaaaggt caacatctag
    16741 tattccagat tcacttaatt cttctcttga agcttcatat tttttagcta cacaaggcat
    16801 tacagataca acataaagtt cttcaggatt gattcctaat attttaggtg catagtagtt
    16861 tttagctata gaaccaaaca taccttgagg agacttacag ctagatgcta agtttaactt
    16921 gtctggataa ttgtgctcta agaagtttac ccatgcagga caacaacttg ttaatatagg
    16981 aagattttca cctttttgga ttctttctat aaattcagta gcttcttcca ttatagtaaa
    17041 atctgcacca aagtttgtat caaatacatg ttcaaatcca agtgctttta aagcagctac
    17101 cattttccct gtagagattg accctggttc taatccaaac tcttcaccaa tagcaactct
    17161 tacagcagga gcaacttgca ctactatagt cttttctttt ttatttaaaa catcccaaag
    17221 tttaggtaca ttatctactt ctgttaatgc tccagttgga cagacagata tacattgacc
    17281 acagaatgta cactctgttt caaccatatc agagttaaag aatgtactaa ctaaagtatt
    17341 aaatccacga ttaactccag ataatgctcc tactgtttgt atgtcattac atacagtctc
    17401 acatcttcta cataatatac acttagaatg gtctttaact aaagatttag tagaagtatc
    17461 tttacctgca aaagatttag aaccttgata tcttattttt cttactccta aatcagcagc
    17521 tatagtctgt aattcacaat ctccattttt ttcacagaca aaacaatctt gtggatggtc
    17581 tgataacaat aattcaacaa tagttctacg agcatttaat gctttagcac tattagtctg
    17641 aactttcata ccttccttta taactgttcc acaagctgga actaatcctc tctctgtctc
    17701 aaccatacaa acacgacaag aagcacaagt gtcaagctta tctatttcat tcatatgtaa
    17761 atgacaaagg ttgtgtattt ttatatttat taatttcgca gcatctaaga tagaagttcc
    17821 actaggtgct gaaacgtgtt tgccattaat agttaaatta actaaactca ttgttattcc
    17881 tcctccaaat aagttatttc ttgattatag cgttaaatgt acaattatct atacaagcac
    17941 cacattttag acacttagaa gtatctattg tatgttgttc cttaacagaa cctgttatac
    18001 aaccagcagg acacactcta gaacattttg tacaaccctt acagtcatct gttataaagt
    18061 aagaaagtaa gttctgacat ttaccagcag gacatttctt atctacaaca tgagctatat
    18121 actcatcttt gaaatattga agagtactta aaacagggtt tggagcagct ttaccaagac
    18181 cacataatga agcagtttgt atagtttcag caaggttttc taggtcatct aaatcttgta
    18241 gagtaccatt accttctgta attttagtta atatttctaa taatcttgta gtacctatac
    18301 gacaaggtgt acatttacca caagattctt caacagtaaa ctcaaggaag aacttggcta
    18361 tatctaccat acagtcagat tcatcaagaa caagcatacc accagagccc atcattgaac
    18421 cgatagaact taatgaacca aagtctatag gagtgtctaa atgttcagtt ggtatacatc
    18481 caccagatgg tccacctgtt tgaacagcct taaatttctt accttcaggg attcccccac
    18541 caatttcaaa tacaatatct cttaaagtag tacccattgg aacttcaaca agtcctacat
    18601 tttctacctt tccaccaaga gcaaagactt tagtaccact agaatcttca gtacctaagt
    18661 tggcaaacca atctccaccc ttaagtataa ttgcaggtat gttagcaaaa gtctcaacgt
    18721 tatttaagca agtaggagat ttccatagac cactcttaga agaactataa gttttcattc
    18781 taggttcacc acgtctacct tcaattgaat gcattagcgc tgtaccttca ccacaaacga
    18841 aagcacctgc accatatttt aattctaatt taaagttaaa tccagtgcct aagatatttt
    18901 cgccaagtaa accgtatttt tcagcttgag ctatggctac ttttaatctt tctatagatt
    18961 ttggatattc tgctcttatg tatatgtatc ctgtatcaga acctatagcg tatccacata
    19021 ttgccatagc ttctagtaca ctatgagggt caccttcaag tacagatcta tccataaatg
    19081 cacctgggtc accttcatca gcattacata caacaaactt tttatctgtt ggaccagctg
    19141 gattttttga agcagcttcc catttagagc cagtagggaa acctgcacca cctctaccac
    19201 gaaggccaga agtttttacc tctgcaataa cttcttgagg agtaagagaa gttaaacatt
    19261 tgcctagagc taaataacca tcattggcaa tatattcttc tatactatct gggtctataa
    19321 gaccacaatt ttttaaagct atacgtaact gttttttgta gaaagacatt tcttcttgtt
    19381 cttcaacttt tttacttaaa gattcttcct catataataa ttcctcgaca actgtatttc
    19441 taattaagtg gctttgaact atcttttcag catcagatgg ctcaactttt acgtagaaaa
    19501 cgttatcagg ataaactttt acaataggac cttgagcaca gaaaccaaaa caacctgtca
    19561 aacgaacact aactttatct tggattcctg atttctttat ttcattttct aattcactaa
    19621 ctatttctag actgtttgaa gatgtacatc cagtatcaca acaaacaagt aattctcttc
    19681 ttaatacatt ttccttagaa taattttttc ttaagctaag attaggtttc agctcatcag
    19741 ctaaaacttt taattcatca aatgaattta ctttacgcat tatttattca cccctcttaa
    19801 caattcaatt ctaattctct ataagtatct aatatttcgc ttacttggtc aggtttcact
    19861 ttaccataaa ctttaccatt tacagtaaca actggagcta aaccacatgc ccccaaacat
    19921 cttaaacctt ctaaagaaaa tttaaaatca ctagtagttt ctccaacttt tatgccaagc
    19981 tgtttttcaa aagcacttaa gattttgtca gcacctttta caaaacatac agttcctaga
    20041 cagacactga ttttatactt acctacaggt tctgtagtaa aataagaata gaatgtaaca
    20101 accccatata cctttgcagg agctactcca agttttctag caacatgaag ttgaacttct
    20161 tttggaagat atccaaatat accttgggct tcatgtagaa cttgtattaa cgcaccttcc
    20221 tttgttgcaa gagagtcaat aaatatatct agttcgtcaa ataattgctt gttgtgtgaa
    20281 ataaaatcgc acataacaaa tccccctttt ctttttaaag ttattatttt tcataaaata
    20341 attaaccatg agttgacccc aacattatgt gggtgaacaa aaccaaaaca ataaagaaag
    20401 aataatatac aacaatttct ttatttataa aaacaatgca aaaaagttac ctattaaaaa
    20461 taaaaactat actagtctat tataatataa aataattcag aatagttaaa aaaaataaaa
    20521 aaaatgagct aaattcaata aaaaaaaaat aatacatata aaaaacttta aaaaataaac
    20581 caaaatgtaa aatttttata aaataaaaga tttataaaac tgctgataat agtcttgaaa
    20641 ttgattcctt gatttttata taagtagacc tagaattata tatatctaat gttatttcct
    20701 tagaatttaa aatatcattt tcaaatataa ttctttgttc caatgctttt tttgaagagt
    20761 acataaatgc attaacttcg aaattaagct caaaacttct gatatccata ttagctgttc
    20821 ctatagagca tatagagtca tctataacta ttgtcttagc atgtaaaaat gcattttgac
    20881 cataagtata gattttagct ccaaacttta aaagttctcc agcatatgaa tatgatgccc
    20941 agtatacaaa gggatggtca ggtttagaag gaatcatcac tctcacatca acaccagata
    21001 aacaggctat ttttaaagta tctataaaag ttgagtcaag tattaaataa ggactctgta
    21061 tgtatatata ctttctagct ttctgaatca ttttaaggta accatattta atctcatcaa
    21121 gttctgatat atctggacca cttgatacta tctgaatccc aatattttca gaaggatgat
    21181 tagaatttgt atcttcttct ataaagtatt tttctaaatc taagtcttct ttagttgtat
    21241 atctccaatc aaggatgaat ctcatattta ggtcaattac gcaatcacca gtaagcttag
    21301 tatgtgtatc tctccataga ccaaattttg gatttctacc taaatattca tcaccaacat
    21361 tatatccacc tacaaatcct accttaccat caatgacaac aatttttcgg tgatttctat
    21421 agtttaagtt aaagtttaca attttcaaga atgatgggaa gaagcttcca actttaacac
    21481 cactttcttt aagtctggaa agtgtactat tttttagtgt tctaccacca actgcatcaa
    21541 ataaaagtct tacttcaaca ccttctttag ctttgtctat aagaatgtct attatttcag
    21601 ttccgatttt gtcatctttg aaaatgtaaa attgtatgtt tatatatttt ttagcttttt
    21661 taagttcttc aagaagactg ttaaaaaatt gactagattc agcataaatc cacacatcgt
    21721 tattattggt ataatgagca ttatttgaat tagccaatgc ataaatcata tccttatgtt
    21781 gatgtatatc tgaatcaatt tcagatgtag attggagttt aacctgagta tctagtatat
    21841 tacttttgat tatcttatca tccttttctt tcaatctaaa catattgttt tttgaaatat
    21901 ttctgccaaa agctatataa agtatgaatc caagagcagg aatcaatact aatataagaa
    21961 gccatgttaa agttgtattt atgtttcttt tttctctaaa gataaggttt agtataacca
    22021 tgaaattaat tatatatatt gtagtaactg ctatttcata tattgacatt tcgaaaaatg
    22081 atatatcaaa cataaaattc cctccttcaa atatttatta aaataagtaa ttatatataa
    22141 taacacaaac atatatctat tatatataat acctcaataa ttaaaaagta aaataaataa
    22201 tcaaaaggta aatttttcaa attcaatata aattatttcg aaattaacaa agttgttata
    22261 taataaatag tataattata tgagac
//
LOCUS       DAEPXW010000065        21843 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.066, whole genome shotgun sequence.
ACCESSION   DAEPXW010000065 DAEPXW010000000
VERSION     DAEPXW010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.066"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            226..927
                     /locus_tag="KRM55_002453"
     CDS             226..927
                     /locus_tag="KRM55_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH1594689.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     KKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
     gene            953..1609
                     /locus_tag="KRM55_002454"
     CDS             953..1609
                     /locus_tag="KRM55_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594690.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            1765..3405
                     /locus_tag="KRM55_002455"
     CDS             1765..3405
                     /locus_tag="KRM55_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH1594691.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            3763..5085
                     /locus_tag="KRM55_002456"
     CDS             3763..5085
                     /locus_tag="KRM55_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594692.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIVVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            5282..6289
                     /locus_tag="KRM55_002457"
     CDS             5282..6289
                     /locus_tag="KRM55_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH1594693.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREKEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            6327..7754
                     /locus_tag="KRM55_002458"
     CDS             6327..7754
                     /locus_tag="KRM55_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HBH1594694.1"
                     /translation="MASTNKNNVTSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVGTDKLNTNTLTEKN
                     KKVIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SVGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQIYMGVEE"
     gene            7896..9161
                     /locus_tag="KRM55_002459"
     CDS             7896..9161
                     /locus_tag="KRM55_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1594695.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            9203..10801
                     /locus_tag="KRM55_002460"
     CDS             9203..10801
                     /locus_tag="KRM55_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH1594696.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNVDDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            10836..11858
                     /locus_tag="KRM55_002461"
     CDS             10836..11858
                     /locus_tag="KRM55_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1594697.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(12259..13662)
                     /locus_tag="KRM55_002462"
     CDS             complement(12259..13662)
                     /locus_tag="KRM55_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1594698.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            14835..15344
                     /locus_tag="KRM55_002463"
     CDS             14835..15344
                     /locus_tag="KRM55_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBH1594699.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            15372..15566
                     /gene="rpmI"
                     /locus_tag="KRM55_002464"
     CDS             15372..15566
                     /gene="rpmI"
                     /locus_tag="KRM55_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBH1594700.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            15622..15978
                     /gene="rplT"
                     /locus_tag="KRM55_002465"
     CDS             15622..15978
                     /gene="rplT"
                     /locus_tag="KRM55_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBH1594701.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            16287..16832
                     /locus_tag="KRM55_002466"
     CDS             16287..16832
                     /locus_tag="KRM55_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594702.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            16834..16925
                     /locus_tag="KRM55_002467"
                     /pseudo
     CDS             16834..16925
                     /locus_tag="KRM55_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605025.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
     gene            17267..19192
                     /locus_tag="KRM55_002468"
     CDS             17267..19192
                     /locus_tag="KRM55_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1594703.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWIINDKFSKTIEVE"
     gene            19593..21497
                     /locus_tag="KRM55_002469"
     CDS             19593..21497
                     /locus_tag="KRM55_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1594704.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDGEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         8229 a         2436 c         4075 g         7103 t
ORIGIN      
        1 aattacaggt taaaaaaata atatgtgaat tttctgatat ttactaatta tgaataaaat
       61 atttaagtat taatgttttt agtgagactt taagacagat aatctcctat taaagatact
      121 atatcttaga taaaataaat taaaacaata taaaaacata acaagattac agaaagaaag
      181 ctcacaataa aatgctgaaa aatttatttt aaggaggaat aaagtatgaa gtttcaagaa
      241 atgattaata gcccaggtct ttggattgtt tctagttttt tagtaattat ttcagttgtt
      301 caagcaatcg tatttatgaa agaggcacta aaagaggctt caaatcttgg tattgaaaag
      361 aaaggaatta aagcagcaat tcgctcagct agtgttacag ccattggacc ttctctatct
      421 cctgttatta cattattatc actggtagct gtgattggcg ctcctacgac ttggatgagg
      481 ctctgtgatg tcggagcagc tagaacagag cttggagtaa tatctcttac atccaattta
      541 tctggggtag aagtaggtag tgctgcattt ggagcagaag ctttttcgta tgcactatgg
      601 gggatggctt taaataactt aggttggcta tttgttgtat ttattttggg tcatagaatg
      661 cgtggaattg ttgaaaagat gaacatgaag tataatccta cttgggttaa aaaactactt
      721 gcaggtgcta cagttggatt atttgcttac cttctttcaa atcaaataaa aacatttgaa
      781 ataccaaaac ttacaccagc aattatttca gctatagtta tgctagtatt gacaacttta
      841 tttaaaaaga atcaacgatt acaagaatta tccttaggta ttgccatgtt aattggtatg
      901 tttggtacac agattatatt atcgtgatta aaacggataa gaggtgataa ttatgtatga
      961 taaaaagatg ataaaaatag ggagaatttc tataggtctt gcaattattg caaactttat
     1021 tcccgctatc tatgtaggta ttcgctttgg tcagatgcca atgctttctg ttatatttca
     1081 aatttggggg ttagtcgctg cgacttatgg ggttagttgg attgttcaac ctatagctta
     1141 ttatcctaca ctaggagctc caggttctta tataggttgg cttgcaggtt ctgttggaga
     1201 tatacgtatg cctgcagcat caatggcaca gaaaattgca ggtgtagaag caggaactca
     1261 tgagggtgaa gttgttggaa caattggtac atgttgttca atctttgtat cagcttctat
     1321 gattaccatt tttaccattg taggctataa agtaattcct ttgttacctg aatttgttac
     1381 taattcattt aattatatac ttccagcatt atttggagca atttatgttg atattgcacg
     1441 taaggatatt cgagctggtg gatgtacgat tgctgtagcg ttagcaatta tgtactttgg
     1501 tgaaaaaatt ggtataccag gtggattatt aacattgttt attgtgttag gtgggatact
     1561 tatcacaagg gtcttctttg taattgataa caataaaaca aaagaatagg attgcttatt
     1621 aaggagaaag actagaatta tttgttgaga aaaagaatag gattgtttat taaggagaaa
     1681 gactagaatt atttgttgag aaaaaagaat aggattgttt attaagaaat atgaatataa
     1741 ataagtcttg aaaggagaaa aagcatgttt gatgttaaaa ttgtcaatgg aataatcgtt
     1801 gatggtacag gaaattcaag atataaaagt gatgtaggga ttgtaggaga caaaatcatg
     1861 gctattggag atttaagtca aaaagaggct aaagagacta tagacgcaac tggaaaattt
     1921 gtatcacctg gttttataga tttccatact cattctgatt tatctcttgt gtatgataaa
     1981 tacacaagaa gccgtatcca tacaggtgta acaacagatg ttattgcaaa ctgtggtata
     2041 ggagttgctc cgataagaga agagaagaag caagagttaa ttgattatct tggaactagg
     2101 ataattggta caattccaac aaaattagag cttcattgga atacaatgca agaatacttt
     2161 gattacttaa ctgaaaattc tccagcagtc aatgttgtag cttatgtagc acaaggacct
     2221 gtacgtatca atgaaatggg attttcaaag gaaccagcta ctttagagca acttaaaaat
     2281 atgaagttgg aagttagaaa agctatggaa gctggatgtg tagctctttc atcaggatta
     2341 gtttatttac caggagcata cacaaagaaa gaagaaatgg ctgaattatg taaggaattg
     2401 ataccataca atggatacta tatatctcat attagagatg aaggtgatga agaaatggaa
     2461 gctcttgatg aagcaattta tatagctaag actgcaggag ttcctctaca tatttctcat
     2521 ttaaaagtta tgggtcataa gaattttgga actattgatg aggtatttaa aaagctagat
     2581 gaagctgagg cagatggttt ggaagtaact tttgattgtt acccatatac agctggaatg
     2641 acatctttgg gtgcactttt acctccttgg gcttttgaag gcggtgtaga aaatatggta
     2701 aaacgattag aagtacaaga aaatagagac agaattataa aagagttgga ggaagggatt
     2761 cctggatggc aatgtttcta ccaattagca ggtgggtgga acggtgttgt actagcctct
     2821 gtaatgactg aagcaaataa atatgtagag ggtaaaactt taatggaggt agccaaaatc
     2881 aatggtgaaa atccatttga tacgttcttt aggcttttga ttgaagaaaa aagtaaaatt
     2941 caagtagttg ttcatacaca aggtcaagag gatacagata aggttgtttg ccatccaaag
     3001 tcatgtatag gttctgatag tatggacctt tctacagaag gtttactttc tcttggaaag
     3061 cctcatcctc gtgcatttgg tacttttgga cgaattttct cttactatgt tagagaaaaa
     3121 ggtatgttga cttttgagga agcagttaaa aagataactt atctttcagc aaaacgctta
     3181 ggcatttata aagaaagggg tctacttaaa gaaaattatt ttgctgacat tgtggtattt
     3241 gacccagata caatagaaga taaagcgact tatagtaatc ctaaacagta tacagtggga
     3301 gtggaatatg tgttggtgaa tggtaaaatt gcattggcag gaggaaagca aactgatgta
     3361 tgtgctggac gtgtaattaa aaatcctctt agcatagcaa aatagaatac attaagaact
     3421 tttataaaaa tagtctttct ttgaatatta aggaaggcta tttttgttaa attaataaag
     3481 attactctac ttgtgttttc taaagaattt aactttaagt agaaaaaaca atatattaat
     3541 tgtaaaatgt aattaatatt aatgaataag atttaaatac aaaaatttaa atacaaaaat
     3601 gtttcaacag atagtcgtaa ttaaaaaact taaagtaact ttttatatta ggtataattg
     3661 attattcaaa attctatgaa tcaggagtcc tgtggcttta gtcatggtag gtttagaaaa
     3721 tgttttaaga gataatagta tcattaggaa aggagagacg aaatgaaaat actttatgta
     3781 ggaccaggta tggtaatcga taaaatacta gcagtaagta aaaagaattt tcctaatatt
     3841 gaagcagatt ttcttagata tgatagatat attgaagtac ctgatttatt ggaaaaatat
     3901 agaggtagag tggatgcagt tctttttaca ggtaagtcgc catttaaatt ttttgaaaaa
     3961 agacaaaaag attttgtatt gtctgattat attcctagac atgaaacaac attgtacaga
     4021 gtgttgcttg aaattacata tttgcttaaa ttcgatatta gtagacttag tatagatact
     4081 tatgataagg ctatgatgaa gagattgtat aaagaaattg gagttgaatt taaggatgaa
     4141 catatgtttt ttgcagagca aaagtattta gaagaggact atataaagtt tgtgcttgaa
     4201 tttcataaat ataattatca aaataatgat gtatgttgtt gtattacagg tcttgaagag
     4261 gcctatcata taatgaaaaa agataatatt ccagtagttt tagccttgcc ttctgaggac
     4321 gtaatggtgc aaagtataaa aaacattcag atgcgttata ttgcaaagaa aaacaatgag
     4381 aatcagattg ttgttcttgc tattaaactg aacatgcctt cagaatattc actaatgaag
     4441 gaagatgagt acgcttatct ttcacaaagg attaagattc ttgataaact ataccatttc
     4501 aatagccgta tagatggtgt tttggtagag cagagtagaa gtgaatttat gatttttaca
     4561 actaaaaaaa tacttgagtt agaaacaaag aaatacagag atatttattt gttggatatg
     4621 attcgtgaag tttcagttat aaacacttat ataggaattg gttatggaaa aacagcaaat
     4681 gaagctaaat ttaacgctta tgagagtatt aagatggctc aaagtcaaaa aaatgatgca
     4741 gcatatgtag tttttgaaaa tggagaaatt atgggaccac taaagccaaa tcctactgtc
     4801 aaagagaaaa atagttttga tgaacgtttt tatcaaattg ctacagagac agggctaagt
     4861 gctaatactg tatataaagt attcaataaa ataataaata gtggaaaaac tgaatttaca
     4921 tcaaaggaat tagctactat atgtggtgta agtattagaa ctatggacag gattatactt
     4981 agattgtgtg attctggtta ttgtgaggta gtgagtgaac agcttatgag caagtatggt
     5041 agacccagta gaatattacg ttttaaacct tttctgttgt tttaaataga tataagtcaa
     5101 aaattaaatt tttatgataa cattttcttt acaatttttt agatatatgt taatatttag
     5161 aaaaatgcat atgtattcat aaaataaact taaaacagct aaaaaatcat taaaaaggaa
     5221 atcgtatgca tgaaatgaga aagttaattt ataacttaaa taaatctggg aggagataat
     5281 tatgggaaaa tatcaggatt caaaaaaagt tgtaagaaat tattttgaag cattagaaaa
     5341 tgctactggg gatgaggttg aaaatgtctt aaagcaacat atgaaatcag attataactg
     5401 gaaaggtgtg tatccatttc gtgaaaaaga aggcactgaa aatgtagcag atgtattttg
     5461 gaagccttta aaaaaatcat tgagtaatat gcaaagacga caagatattt tcattgcagg
     5521 aacaaatgag attgacaata gtgaatgggt aatgagtatg gggcatttta tgggactttt
     5581 tgataatgat tggcttggca ttaaacatac tcgtaaaatg attagtttaa gatatgcaga
     5641 atttaactgt gttcaagatg gtaaaattgc taaaactgga ttatttgtag atataattgg
     5701 gtttatgatt caagcaggag ttaatccatt gccaccacaa acaggttcat attttgtata
     5761 tccagggcca attgaccata atggattact ttttgaagat gcagatgaag ttgaaggagt
     5821 aaaaacttta gcattagtaa ataaaatggt agatgattta tctgaactaa atgaaagtgg
     5881 tgctatggga tgcccaccag aaatacttga aaaatcttgg gctaaagata tgatttggta
     5941 tggtccaggt ggaattggtg cttcttatac tatacctaga tatcaagagc aacaccagct
     6001 accatttaga aataatttaa aaggaaagac ttttaatggg catgtatgta gatttgcaga
     6061 aggtaatttt gcttgtttct ttggatggcc taatctgact aatgtaccat gtggaggttt
     6121 tttaggatta ccaggtggag aggttaaagc agatatgcaa gttgttgatg tttattatcg
     6181 taagggcgat aaacttcaag aaaactgggt gttaattgat attccttatt ggttgaaaca
     6241 acaagggctt gatattcttg agagaactaa aagtattttt aatgcttagt tatgcatacg
     6301 tattctaaaa caaaggggga tataaagtgg catctaccaa caaaaataat gtaacaagta
     6361 aagaggaaga aaaagaagtt tctacaagtg ggcttgaatc atgtacggtt aaagaaaaca
     6421 aagctaaaat gaatcaaact aattttagta atataaatga aaatcaaaca aatgagaata
     6481 aaacgaacac atataaaaga aatatagata aaggaaatat agataaaggg aatatagata
     6541 aaacaaacac aaataaatcc gacataaata aagttaacat agatacagtg ggtacagata
     6601 aattaaatac aaatactctt actgaaaaaa ataaaaaagt tatatttaag ggggaagata
     6661 atatgtcatc tacaaaaatt tactatggag attcattaga agtaacgcct gttggagtaa
     6721 tggattacaa tgatttttca aaacagacaa aaagggaaca ggaaatacct ggatttgatt
     6781 ctaagtatag agattttgta gattatatta tgaagattac acataatatc tgggaagaaa
     6841 aaggtatagg tgttatttat gatacatatc acaataatgt tacaatgcat tgtggctctt
     6901 caaatttagt tggtattaaa gatgttattt ccaatactct tcaaacatta catgcgtttc
     6961 ctgatagaag attaattggt caaaatgtaa tatggtctaa ctttggtgct gatggttttt
     7021 tatcttctca ccgtgttttg tctacagcaa ctaacttagg tgatagtaat tttggaccag
     7081 caacaggtag aaaaataaac tttagaactg taattgattg tgccacaact aacaatagaa
     7141 tccacgaaga atggttggtt agagataatt tatggattgt tactcaatta ggattaaacc
     7201 ctcaggaagt agcaaagagt atggcaaagg caagtgaatc taaagtgctt agtttacaat
     7261 caacttatgg tatctgtgaa tctatggatg gtcaatttat gccaactaag tatcaagcaa
     7321 aagatgattc tgttggcgaa atgatgcttg aaatgacaag ccgtatttat aattataaat
     7381 atataaatga agttaaaaaa tactatcatg ataatgcagt agtacatttt atatgtgata
     7441 aagatttaaa tggttatgat gagattcaag gaatgattgt aagtttactt gcatcaattc
     7501 caaatggaag ttatgaagtg gaaagagtaa cttgtaatca aagagaaaaa aatgaaggtt
     7561 atgatgtatc tgtaagatgg agattacgtg gaataaatga aggtatagga ttttttggac
     7621 agccttctgg aaagcatata gaagtaatgg gaatcaatca ttatcatata ctacaaggta
     7681 aagtaaagga ggagtggata acttttgatg gtatggatgt attaaaacaa atttatatgg
     7741 gagtagaaga ataaagctgt ttagagtata aatagttttg aaatatatag ggaagtattg
     7801 ctttataaaa tttaagtggg gaatgtatat gaaaaataga tgtttaaact tttagcaaaa
     7861 ttatgactaa atttaaaagg gggaattata aaaatatgaa aacaacggtt gaaatagaaa
     7921 atgatatcat attaggaaaa gactattcaa acctaaaaag aggaattgca tttttttcaa
     7981 ttgctttaat atactttttt tattgctaca attttatggt gggtactttt attaaaccaa
     8041 caatgattta tgctttagca gatgggggat ttggtttttc attaaaacaa acagaagaaa
     8101 tatttgcagt tatgtctttt ggtacaattc caggtacatt tatttttggg gtgatttcta
     8161 caaaaattgg gaagaagagg actttaatta gcgttgcttt actgattgga ttgacaacat
     8221 ttataccaat gttatctcct acaaatatta tgttatggaa aatagcacgt ttgtgtacag
     8281 gagtagtgtt gggaggcgta tttggaacag ctatgccttt agttgcagat atgtttccaa
     8341 gtaaatatcg tggtaagtta gctgctatat taactgcttt attttcatta gcaatgattt
     8401 ttggtgggaa agtatatggc gttttaggtg atgcaaattg gcaaatattg atgtatactg
     8461 cgattatacc acctatagtt ggagctatct tagcaatctt ctttgtgcca gatgatttgg
     8521 agtatacaaa ggaattagtt aaaaagggaa aagaaactgg tgaaaagatt agctatataa
     8581 gtatgtataa gggaaaatac ttatggattg gattgggaac gattctttta tcaggtgcaa
     8641 attttacagc atattcagca ttttcaaata atgcaactac atacctagtg acaggaatag
     8701 gaatgtcagc agcagtggct gggtctatat atagtttaca aggaattggt caattagtag
     8761 gatatttatt ctggggttca attgcagata aatttggaag aaaaatacct tttataggta
     8821 tggcattagc agcagtattt gtttttatat atacaaaatt aggtggagat aatacaacaa
     8881 cattctatat gatatcagta ttactaggtg ttgctgttgg atattctgga gcatggggag
     8941 catactacac agagttgttc ccaagtaaat atcgttcgtt gtcatctggt atgtcattta
     9001 atggaggaag gattatatct acgtttgcaa tacctgctat agctggtaca gcttctggta
     9061 ctttaggtat gatgactatc ttttacatat caatcgcagt ctttgtagca ggtgctattg
     9121 tatggttatt cttaccggag acgttaaata ataaaaaata aaatactagg aatttatttt
     9181 gttacttaga aaggggtggc ttatgatttc atcaattgat gtatgtatta taataggata
     9241 tttgctatta atgttagtta ttggttatta ttcaggaaaa gataataaaa atcaagaaga
     9301 ttatttcttg gcaggtaggt caatgccatg gattccaatt gctttatcag ttgcagctac
     9361 tatgattagt gcaaatggct ttataggtgg tcctggatgg gcatatgtag atggaatgta
     9421 tccagtaatg gttaatatta cagtaccttt agcaatattt tttgcactga gcattaccac
     9481 cccagttatc tataaattaa aaataacctc tatatatgaa tatatgggac ttcgtttagg
     9541 aaattattca agaggattaa ctattattca attttttatt aattcattga ttcaagctag
     9601 ttctatggta tatattccag tgcttattat tcaaatgatt actggctggt cactttatgc
     9661 tttagtccca atagttgtac ttgtatcaat tatatacact ctattaggtg ggattaaggc
     9721 agttatatgg actgatagta ttcaaatgat agtagtaata agtgctgtat ttatagtaat
     9781 tattgtagcc ttaaaaggaa tgaatctaag tttctttgat acattacaaa ttgcacaaca
     9841 gagtggaaaa ttaaatacat ttgatttcag tagggatatt tcagtgacaa atactttttg
     9901 ggctacttta attggtggaa ctgtaatgtg gataagatac ttttgttttg accaatctca
     9961 agtacaaaga gttttaacat ctaaatcttt aaaatgtgca aaaaattctt ttgtagttag
    10021 tgcatttgtt atgaatttag tttactactt tatgctattg gtaggagtaa ttttatttgt
    10081 tttttatggg ggaaggacat ttgaaacttc aaatgaaata atgattactt ttattttaaa
    10141 tgaacttcca gtaggagcca ttggaattat tattgcaggt gtgtttgcag cagcaatgtc
    10201 tagtatcgac tctatattaa acagtatgac aactgttttt acgaaggata tttatgagtt
    10261 ttatttcaaa aaagataaca aagaatcatc attaaaagtt acaatgatta taactgtagt
    10321 tataggagtt gttatgacag gttttattat tatgggattt ggaggaagca tcaaatcaat
    10381 tcttgacctt gttggtaact atatctcata ctttgctgga ccagctacag gtgcatttgt
    10441 actagcaatg tttacatata aagctaatga taaaggagta tctattggtt ttattgtagg
    10501 gttagtttta ggatttttta tttctaataa atataatgtg agttggttgt ggaatccagc
    10561 aataggtgct acaataacat tgatatttgg atatattttt agtgtcattt taaagaaaaa
    10621 tcataatgta gatgatatta aaaaatacac tgcatttggt atgagaaatc accttatttc
    10681 tcaaggaatg gataaagtag atggagtatc tatagtgcca ttttctttag gtaaacaaga
    10741 actaattgta ttagcttttt ttattatcca atatattata ttatttttga tacaatttta
    10801 agaagaaata ctagatattt aaggagaaat actaaatgaa tcaaaagaaa gttcattata
    10861 ataaatcggc tacctcaaaa gatgttgcaa gattggcagg agtatctcaa tcatctgttt
    10921 caagagcatt tggtagtgca aatggaaagg gcgtaaaacc tgaagtaaga gaaagaattt
    10981 ttcgtgtagc aaacgaaata ggatatgttc ctaatttggt agcacgggga atgattagtg
    11041 gaaaaactaa tgttatagga ttgatagttg gtgatagtct aggtccattt tacaatagaa
    11101 ttatcaattt atttgtagaa aaaattcaag agataggtaa acagtgtctc gtttttaaag
    11161 ttcctagaca acaaagtata gatagtataa tttcaaaagt aattcagttt caagtagaag
    11221 ctgtgattat tacagcttcg gccatgaata aggtgatggc tgagacttgt gaagaaaaca
    11281 atattcctgt gattcttttt aatcgtttta tacctggtat aaaaataagt acagtctatg
    11341 tagacccaat tgaaggtggg ggcatggctg ctgaatatct gcttaagaaa ggtcataaga
    11401 atataggata tattcaattt acgagagaaa caagtgaaga aatggaaaag aaaattggat
    11461 tttattctaa gttaagacaa agtgggattc ataaccttaa agaagaatct gcaaactatg
    11521 attatgattc tggatatgaa gcaggtaaga gaatgttagc attatcaaat cctccaacag
    11581 caattttttg cacaagtgac ttgatagcta ttggtgtaat ggatgctgca aggtttgagt
    11641 acaagttgag ggtgccagag gatttatcag tgataggata tgatgatatt caaatggctt
    11701 catggaagag ttataattta acgacgatta gacagccact agatttgttg attgaaaaaa
    11761 caattaacat acttaagtcc ttattaaatg aagaaaatcc agagtcagtc gttgaaatgt
    11821 taaaacctga attgattgaa agaggttcta cactttaagt ggtagatatt taattaagtg
    11881 gtagatacct aattaagttg tagatatctg ataagaaatt tttaagtttt caatcgttct
    11941 aaattgtgag tataaaaatc tactaaattt agttatgtaa aatataaatt ataagtgtag
    12001 aaactaggct actagctttt ataccacttc aaacattact ggaggtagtt aagtttacat
    12061 cagtttagtt ttatgtagat ataatattct gtaaatagac aaaattaaaa tatgtaatta
    12121 aaatatgtaa gtgtctcaaa atgaaatttt tagtttatga ggcacttttt tgtataaaat
    12181 caaatgtatt tttataactt taacaataaa aagaggctta tctctatttt gagacagcct
    12241 caaattttta aaactatatt agtttacagc ttcttttcct atcaaatctt ttaactcttc
    12301 atgagtcata gtttcttttt caaataagaa tttagaaaca gaatgtaaat cttcaagatt
    12361 atcctttaac atctctaaag tctctttata acaaatttca actatacgat ttgcttcctt
    12421 ttgaacctta tcacataaga aagtcttatc atttccatca atagtcataa atcctaagtt
    12481 actcatacca tattcacaaa ccatttggtt agctatttca gtgactttct ttaagtcgtc
    12541 ctttgcacca gtagatttat gattaaatat taattcttct gaagcctttc cagcaagtaa
    12601 tatttttatt tttccaatca actcatcctt agtataaata tatctatctt catcaggtaa
    12661 ttgaagaaca taacctaatg cttgtcctct aggaactata gatatttttt gtataggaca
    12721 aattcctact atatcactta caagagcatg tccagcttca tgatatgcta ctattttttt
    12781 ctctttttca accaatgcag agtttttaga ttctagccct gcaataactc tttcaagtgc
    12841 cttgtcaaaa tgttctgatg taatacactc actgtcatct ctaactgcaa atatagctgc
    12901 ttcatttgct atatttgaaa gatgagcccc attgaaacca tgagtttttt tagctaaaag
    12961 ttctagattt acagatttgt ctataggttt gtcatctgta tgtaccttta gaatttcaaa
    13021 tctagtgtga tagtttggtg cacctatatg aatgtgtctg tcaaatcttc ctggtctaag
    13081 taaagcttca tctaataagt caagtctatt ggtagcacct attattaata cattggaatc
    13141 tttattaaat ccatccattt caactaaaag ttggtttagt gtttggtctt tttcgttgtt
    13201 actttcaaga tgtctctttg ctcctacagc atctatttcg tctataaata ttatacttgg
    13261 agcttctttt ctagcttttt caaatagagt tctaactctt tttgctccca cacctacata
    13321 tttttcaacg aactctgaac cagtaacatt gaaaaatgat gagtttgttt caccagctac
    13381 agcagatgca agtagggttt tacctgttcc tggaggacca taaaataata ctcctttagg
    13441 tatttttgca cccatttttt gatatttttg tggtgacttc ataaaatcga ctatttcaaa
    13501 tagttcttct tttacttcgt ctaatccagc aacgtctcta aatgtagtct ttggttttgt
    13561 agaaagtgaa tcatctgttt gattatctct ttccattttt gtctgtgcaa agacaggagc
    13621 tggattgttg attttcttaa aaaagttgtt tagcattttc atattcacac ctcaggtaat
    13681 taattattgt taatcaattt tatattttcc atatttacta ttttttatta tttatttttc
    13741 atggaaaaaa tatacatgtt atctaaataa aaataaattt gtaagatgta tgaaaaaatg
    13801 aatttatgta tatagagatt tctacttatg tattgaataa agtattacaa attataaatt
    13861 atgtattgat tatatattga gtaaagtatt ataaagcatg tattgattaa gtatttatta
    13921 agtattgaat aaaatattac aaatttagtt gaaatgaaaa tgataaaaaa tgttgtacta
    13981 tattttacaa atcatataaa tagagaaatt gttgtagcgc aaagtagtag gtagtatatt
    14041 agaatataat tataggattt gttgtgtagt atagtagcat attagaatat aatataggat
    14101 ttgttatgta gtatagtagc atattagaat ataatatagg atttgttatg tagtatagta
    14161 gcatattaga atataatata ggatttgtta tgtagtatag tagcatatta gaatataatg
    14221 taggacttgt tatgtagtat agtaacatat tagaatataa tgtaggattt gttatgtagt
    14281 atagtagcat attagaatat aatgtaggac ttgttatgta gtatagtaac atattagaat
    14341 ataatgtagg atttgttatg tagtataata gtatattaga gtacaatata gaatttgtta
    14401 tgtagtatag tagtatatta gaatacaata tagaatttgt tgggtagtat agtgttatat
    14461 tagaatacaa tataggattt gttatgtaga atatatagag tcatgtagaa tatacatata
    14521 taaaaggatt ttgggtataa atttaaaaat taatagcaaa atgagtagta tagacatata
    14581 attagtagta ggaagtaatt aaatttttcc taaacaaaaa aaatagttgc aaataatttg
    14641 attaagtgat atagtaaata aggtaagaat aaaacaaaga agaagtccgc ttctcacctt
    14701 acgccggagg ttagtaaggt aaatataagt taaagcttaa ttttaattta agtttgttta
    14761 aatttggtaa cttatattgc ggatgattac gtcatccgct ttttatttta taaaaatttt
    14821 ggaggtgtcc tacaattagc aaagaattag caatcaatga acaaataaaa gataaggaaa
    14881 taagagtcct ttcaccaaca ggtgaacaac ttggagtaat gcctactaaa gaagctcaag
    14941 caatggctaa tagcaaaaac ttagatttgg ttcaaatctc gccgaatgca aatccaccag
    15001 tatgtaagat aatggattat ggaaagttta gatatgagca agcgagaaaa gagaaagaag
    15061 ctaagaaaaa acaaaaaact atagttgtaa aagaagtaag acttagacca ggtattgaac
    15121 aaaatgattt aaatacgaaa gctaataatg ctataaagtt ccttaaaaaa ggggataaag
    15181 tcaaagttga acttagattt agaggaagag aattaggaca taaagacata ggtaaagaag
    15241 ttatgcttaa gtttttagat ataataaaag agtttggaga accaacaaaa gcccctgcat
    15301 ttgagggtaa taatatggtt gtaattatag atccaaaaaa atagatgatt aactgagagg
    15361 aggaatttgt catgcctaaa atgaaaactc atagaggtgc agcaaagaga ttaaagaaaa
    15421 caggaactgg aaagttaaag agagctaaag cttttaaaaa acatatatta actaaaaaat
    15481 ctgcaaaaac taaaatgaac ttaagaaaat caactctagt aagtgatgga gatgctaaga
    15541 gaatagcaca attattacca tactaagata cagattgtaa ataataacta tagaagaggg
    15601 atataaaagg aggtcataac gatggcaaga gttaaaaaag ctatgaacgc tcgtaaaaag
    15661 cataagaaaa tattaaaact tgcaaaagga ttcagaggat ctagaagcaa attatataga
    15721 ccagcaaata cattcgtaat gaaagcatta aaaaatgctt atataggaag aaagttaaag
    15781 aagagagact tcagaaaact ttggatacaa agaataaatg cagctgctag aatgaatgga
    15841 atatcttatt caagattaat gaatggatta aaattatctg gtattgaagt taacagaaaa
    15901 atgttatctg aaatggctat acaagaccca gaaggatttg caaaattagc agaagttgct
    15961 aaagcaaaat tagcttagta ttgaatcatg agatgtaaag tctttgagtt atataaataa
    16021 ttcaaggact tttttatttt ttgaaaaata cttattagtg tcatgtacaa ccaattttat
    16081 aatgataaat aaataagcaa tacaatagaa ttttatgaga tttattataa gaattgttac
    16141 aattatttat gatagctata aaaagtcata gtaaaaatga tactgatgta tgttgatata
    16201 tgtataaagt ttccaatcaa tcttgaatta atattatcaa catgataata ttatcttatt
    16261 aataatataa ataaggggga cataatatga atgaaaaact aatggattgt tttgtaaacc
    16321 caattaaatg caagttattg attgaaattt tttcaaataa tcgaactaca gctaaacaat
    16381 taggagaaaa atttcaagat atatcaaagg caacacttta tcgttacctt aataaaatgt
    16441 tgaaagatga tattataaaa gtggttgaag aaaataaaat aaggggaact gttgaaaaag
    16501 tatatgctat gaagttagat atagctgatg atgtgaacaa aattatagat gagaactctg
    16561 gagaagaata tgctcaactg tttactcaat atatgatggg atttttaaga gaattttatg
    16621 aatacgctga aagaaaggaa aaggatatcc taaaagatgg ttcaggattt tctgtctgtc
    16681 cagtatatgc tagtattgat gagatagttg aagtgagtaa aaaaattgct agtatactag
    16741 aacctctaag aaataactca catgaagaag gtagaagaat gcattctata ggagtgataa
    16801 ttactccacc taaagaggat gaagggaaat aaatctgatt tacatggggt agagccaatt
    16861 tatacaggga atcgttttat gatttacata tgtatccaga gcaaagtatc tctgcttgga
    16921 ttgtacttca ttgtaccatt tcatccaatg acttggagtg gtacaatgaa gttttttaat
    16981 ttttcatatt aatgctaaag aaatgaactt tagaccacat atgcaattag gttgcattat
    17041 acaattagac cacatataca aaataaaaat cagtattttt atagcagata aattgactgt
    17101 tattcttctt aaaaatcatc tattagttat tgttagcata ttgaaagaaa ttatagtaat
    17161 ctattgaata aatgaatatt gcccataatc atataaactg ctatagttta aaataaagca
    17221 ggacgttaaa ttttatagta atctaaaaat ttaagagggg gattttatga aaataaaatt
    17281 tgttattatg ccattggtga tatttttaat ggtattattt gtggggtgtc aaagtacaaa
    17341 agatacagaa gttaaagcaa aagatacaga aattaaaata ttaggtacag gtgatttgca
    17401 ttcaattttg acagactcta tggtttcgta tgtaaatgag gaaagggaaa agaataaaaa
    17461 tctgcttatg gtagatgcgg gagatttcta tggcacacaa agtagagaaa tgtgggaatg
    17521 gtcttctgga aaaaagttaa ttaatattaa aagaaatggt agagcagagt atgatgacat
    17581 aattaagagt agtaaagatg aagtacctat agttaaagat atggcaaagt tgaaatatga
    17641 tgctgtagtt ttgggagata atgaatttgt ttcaaatgat aagcaaagtc ttgataaact
    17701 agtttctgat tttaaaaata ataatatgcc attggtatca gcaaatatat atgaacaatc
    17761 tggagaaaat tatgtacaac catatgtaat gaaaaatatt aagacagatg agggcaatgt
    17821 aaaagttgga atactaggtc ttactataaa agaagtaggg gaaacccttg gtcttgagga
    17881 ttttgaaaag gataaaaaag ctagagagct tggagaacaa gctgattaca aaggaaaatt
    17941 atatgcaaat gatttagtag aagatgcaaa aaaatggata aaagttatgg aaaaagaaag
    18001 tccagacata atagttgcag ttgtacactc aggggaagaa cctaaaacag atagaaatcc
    18061 aggaaataga ataaaagagt tagcaactac agtggatgga atagatgcaa ttgtagctgg
    18121 tcatactcat gaaaaaatag atgaacacaa atataaaaat aaatctggag atgaagtaat
    18181 tgttacacaa ccaggttggc atggagatag agtatcagag attaatttca aattaaataa
    18241 agagaatgga aagtgggaca taaaggaaaa gtctagtaaa ttaaaaataa ttgataaaga
    18301 agtaagcata gttgctactg cagatttaca ttcacatttc tctgataaat taacagttga
    18361 ccttgttaat gaacgtagta acccaattga acctgttgta gtagatgcag gcgacttctt
    18421 agaccctcaa acagatgaaa tgactcaatg gtataaagag tggaaaagta taagagataa
    18481 taatagtgat aaaacgatta gtagatgccc aatggtcatg gatatgaatc agggaatgta
    18541 tgatgcagta gtacttggaa atcatgaatt tgtatctgaa aaagatgaat tttggtcaga
    18601 tgaacgcctt ttagatgctg ttatagagga ttttgaacag gtggcaattt ctgtgttatc
    18661 ggcaaatata tataggcaat ctggtaaaaa ttatgttaaa ccatatatta taaaagatgt
    18721 ggagacgagt gaaggtaatg taaaagtagg aatattggga cttactataa aagaagtagg
    18781 taaaggtctt aaaaatgtaa acttacaaga gcaatttcaa tataaggata aattgtatgc
    18841 aaatgattta gtggaagatg caaagaaatg ggtaaaagtt atgaaaaaga aaaaaccaga
    18901 tataatagtt gcagttgtac attcaggaga agaaccaaaa aatccaaaac atccaggaaa
    18961 tagaataaaa gaactagcaa ctacagtaga tggaatagat gcaattgttg ctagtcatac
    19021 tcatgaaaaa atagatgagc atgaatataa aaataagtct ggagaaaaag ttatagtgac
    19081 acaaccaggt gagcatggta aatattattc taaaattacc tttaaagtaa ataaagaaaa
    19141 gggttcgtgg attattaatg ataaattcag taaaacaatt gaggttgaat aactttataa
    19201 aatttataga taaagtaaat tatctgatat tgacatgata tataagataa agtttctaat
    19261 attagtataa tgcataatgt gaaatatttt aataataaga gaataaacaa gacaaataaa
    19321 aatattttaa catgtaagat atagtatgaa ctattatact aatgcttact ttataatttg
    19381 aacatattag aataagtctt atttgaaaat tttagtgtat tagagtaagt attattttac
    19441 cagtaaaaaa tattgagaac tatatgtaga tttgcttaaa aaggaattta catatagttc
    19501 ttttcgtata ataaatagta caatcttata tggtaaagat aaagtgtgat attaaatttt
    19561 attatcatcc aaaatctaag gaggagtctc ttatgaaaat aaaatttatt atagtagcat
    19621 caataatatt tttaatagta ttacttgtgg ggtgtcaaag tactaaagac acagaaatca
    19681 atgtactcgc cacaagtgat ttacattcaa ttattccaga taatttaatt tcctatgtag
    19741 aagaggagag aaaatatgat gagaatctac ttatggtaga tgcaggagat ttttttgaca
    19801 tgcaaagtgg tgagatgaat aagtggttta ctggtcaaaa attagtaaga tttaaagatg
    19861 ggataccaga gtacaaaaaa atagctgaac cacgtgaagg agaagttcca ttggctaaaa
    19921 aaatggcaaa gctgaagtat gatgcagtta catttgggaa tcatgaattt gtatctaatg
    19981 acaagcagag ccttgataaa ttggtttctg attttaaaaa taacaatata ccattagtat
    20041 cagcaaacgt atatgaacaa tctggagaaa actacgtaaa gccatatgta atgaaaaata
    20101 taaatactga caagggaact gtaaaggttg gtatacttgg tctgactata aaagaagtag
    20161 gggaacgttc aaggtttaaa agttttgaac aagataaaaa ggctagagaa cttggggaac
    20221 aacctcaata caaagggaaa ttatatgcaa atgatttagt agaagatgca aataagtggg
    20281 taaaggttat ggaaaaaaaa gaaaagccag atataatagt tgccattgta cactcaggtg
    20341 aagagccaaa aaatcctaaa aatccaggaa atagaataaa agaactagca acaactgtag
    20401 aaggaataga tgctattgta gcaggtcata cacatgaaaa aatagaacag catacatata
    20461 aaaataattc tggtgaagaa gtaatagtaa cacagcctgg agctcatggt aatagtatat
    20521 caaagattaa ttttaagttg gataagaaga atgataagtg gtttataaaa gacaaatata
    20581 gtgaattaaa ggtttttgga aaggaagtaa atataattac aacttctggt ctgaatccaa
    20641 aattttcaga tgaaatggca gttaatttgt ttaatgaaag agatagagat gttcaaccta
    20701 tatttataga tactggagat tttttaaata ctaatacaaa agaaatgact aagtgggcta
    20761 aagagtggca atacaatgaa aataaaggca tctataaaaa aataaatgaa tggccaattg
    20821 tatatcttgg ttatgatgct gtagtacttg gtagccatga atttacagag gataaagaga
    20881 cttttgagga aaaaaaatct acattggatt atattataga aaactttgaa gaaatgaaga
    20941 taccagtatt atcagctaat atatatgatg aatctggaga aaattatgta aaaccttata
    21001 taattcataa tgtagaaact agggaaggaa atataaaggt tggagtatta ggtcttacta
    21061 ctactgataa ggatggagaa gacttaagta gctcaagctt aagcaaagac tcaaagactt
    21121 cgaaaattcc tgaagaaaca ggaaagttat atactaacaa tctagtaaaa gatgcaagcg
    21181 aatgggtaaa agttatgcaa aaggaaagtc ctgatgtgat tgttgcagtt gtacattcag
    21241 ataataatag tactctaaaa aatccaagta gtgaagtcaa aaaacttgca atgtcagtag
    21301 atggaataga tgctattgtt gtaggtcata cgaaaaataa ggtagaagaa catatttaca
    21361 aaaataagtc tggggatgag gttatagtaa cacaatctgg agaggattgt tattcaaaaa
    21421 taagtcttga actaagaaaa gaaaatggca agtggaatat cataaacaaa tatagtaaag
    21481 caataaaaat gaagtgaatt tattgatata taaaccatta ttaatactga ttctacaata
    21541 taattaacac tgatttttat aatataataa atactgattc tataatataa ttaacactac
    21601 tttttataat gtcatcaaca ctgattctat aatataatta atactacttt tttaaatata
    21661 atcaatactg attccataat ataattaaca ctactttttt aaatataatc aatactgatt
    21721 ctacaatatt attaatacta ctttttataa tataatcaac actacttttt acaatataat
    21781 caatactgat tctataatat aattaacact actttttaaa tataatcaat atcgattcta
    21841 taa
//
LOCUS       DAEPXW010000066        21822 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.067, whole genome shotgun sequence.
ACCESSION   DAEPXW010000066 DAEPXW010000000
VERSION     DAEPXW010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21822
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.067"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            57..362
                     /locus_tag="KRM55_002470"
     CDS             57..362
                     /locus_tag="KRM55_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594705.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            770..1459
                     /locus_tag="KRM55_002471"
     CDS             770..1459
                     /locus_tag="KRM55_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594706.1"
                     /translation="MDILLVEDDRNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNTIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            1459..2376
                     /locus_tag="KRM55_002472"
     CDS             1459..2376
                     /locus_tag="KRM55_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1594707.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANIDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            2449..3375
                     /locus_tag="KRM55_002473"
     CDS             2449..3375
                     /locus_tag="KRM55_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594708.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            3372..4052
                     /locus_tag="KRM55_002474"
     CDS             3372..4052
                     /locus_tag="KRM55_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1594709.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTINLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            4150..4485
                     /locus_tag="KRM55_002475"
                     /pseudo
     CDS             4150..4485
                     /locus_tag="KRM55_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            5549..6199
                     /locus_tag="KRM55_002476"
     CDS             5549..6199
                     /locus_tag="KRM55_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1594710.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            6537..8603
                     /locus_tag="KRM55_002477"
     CDS             6537..8603
                     /locus_tag="KRM55_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH1594711.1"
                     /translation="MKEVVGSLKKITKERIEDTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYIYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMQGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQRLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            8620..10575
                     /locus_tag="KRM55_002478"
     CDS             8620..10575
                     /locus_tag="KRM55_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH1594712.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRSKPKAGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSFDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            10591..11781
                     /locus_tag="KRM55_002479"
     CDS             10591..11781
                     /locus_tag="KRM55_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH1594713.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            12960..13334
                     /locus_tag="KRM55_002480"
     CDS             12960..13334
                     /locus_tag="KRM55_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1594714.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLIRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYQED"
     gene            13336..14193
                     /locus_tag="KRM55_002481"
     CDS             13336..14193
                     /locus_tag="KRM55_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594715.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            14196..14834
                     /locus_tag="KRM55_002482"
     CDS             14196..14834
                     /locus_tag="KRM55_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH1594716.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGIFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            15845..16579
                     /locus_tag="KRM55_002483"
     CDS             15845..16579
                     /locus_tag="KRM55_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1594717.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLDLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIETLKNLIIE"
     gene            18149..19405
                     /locus_tag="KRM55_002484"
     CDS             18149..19405
                     /locus_tag="KRM55_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH1594718.1"
                     /translation="MIEKFKTLIWIKIIIRIKSVYKTYGGLFLLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASSVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            19468..20661
                     /locus_tag="KRM55_002485"
     CDS             19468..20661
                     /locus_tag="KRM55_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH1594719.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            20862..21242
                     /locus_tag="KRM55_002486"
     CDS             20862..21242
                     /locus_tag="KRM55_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1594720.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT         8209 a         2338 c         3699 g         7576 t
ORIGIN      
        1 taaaaataat aaatattttt atagtagtag ttaattatta ataaggaggg gtcaaaatgc
       61 ctagcatgat tatggaagtt gtaggagtac tatttatagc tattggatta atcttgacat
      121 tcattgaaat aaaaggaaat ttcccttctt tttatggttt tggtcaaaat tctataggga
      181 aaaatgctgt aggtattata gcagcaggaa ttgctttaat tttctttaga aatggcatag
      241 atagcataga ttctatagct acttatggtg tatttttagc aatagaactt gttgtaatag
      301 ttgcatattt cttaataaga aaaaaattta ctaaagaaga taaacattta agaactaatt
      361 aactaaatta tctactataa aattggaaaa ttaaaaacaa ataaaagttt gtttttaatt
      421 atttaaaatc caaatttgat tatttttaaa gaaactatgt tctgtataaa actagaatgt
      481 ggtttctttt ttatgtataa aatatttttt agcaaaagtt aaaaggtgtt ttataatata
      541 aaatagttaa ttgtagatgt taataaaaga aaattatgta tatttcagat aaagataaga
      601 gagtatacta tattttaatt cttttttcaa taaagcttat tgaaaagaac tttaacttag
      661 aagagtatca ccaaattgca gatacaatat cataagcagt tatttattga caaccctttt
      721 taataaatat atcatttgaa gtatactgac gaaaaggagt tgaataataa tggacatctt
      781 attggttgaa gatgatagga atattcgaga aatggtatac gattttctga ttagtgagaa
      841 ttactctgtt aaaactgcca ttgatggaaa tacagctatt gaaatattta aaaattattc
      901 atttgatatt attttactgg acttgatgtt accaaagtct agtggttttg aagtattaaa
      961 atatatacga agtgtgagtg ttgttcctgt tattattact actgcgaaag atagtgacac
     1021 agataaaatg ctagggctta atcttggtgc agatgattat attacaaagc ctttttcaat
     1081 cgtagaattg cttgcaagaa ttaaagctaa tattagacgt gcaacagtgt acagcagttc
     1141 aagaaactct caagatatgg ttattcagta taaagatttg attataaaca tatcaaaata
     1201 tgtagtttca aagaatggaa ttgacttaaa cttaacacat acagaatttg aaattgttaa
     1261 attactagcg actaatcaag gacgtgcttt ttcaaaggaa caattataca acactatttg
     1321 gaaagaacct tattatggaa atgaaaatgt gctaaatact catattaaca ggttaagaaa
     1381 taaattgtct gatggtatag aaaaaaataa ttatattaaa actctttggg gaattggcta
     1441 caaaatggag gaagaataat ggagttattt ttagttgtaa tttctattgt actatttgct
     1501 ctctacttaa aagaacgaaa taaatcaaag aaaatggaaa gtgattataa gtatatcaat
     1561 tcaagacttc gtgacataac aaatgatgat gaaattaatt atattttagt accatctgat
     1621 atttcgattg taaaagaaac agcagtagat ataaataaac ttcttgaaaa gttttacagc
     1681 aggcaaatta attataatag aagtgaaaaa gcgatattgc aaatatttac aaacatatca
     1741 cacgatttac gaactcccat cacagtatta aagggttata ttgaaatgct atatcttcaa
     1801 agtcaaaaag aagaattatc ttcttcaatg agagcaactg tggaaaaaat gcaaacaaat
     1861 tcaaatgagc ttgttaattc aataaataac ctgtttaata tggcaaaaat ccaatctgga
     1921 gatatgatat taaatcttca aaaatccaat ctaacacaat tatgtcatga gattatttta
     1981 gagttttatg atttgctaga taaagaaaac tttaatgttg aagttaatat tgaagataga
     2041 cctatatatg caaatattga cacagaagca ttacaacgta tactcaaaaa tttaattgat
     2101 aatgctataa aatatggttc agatggtaga tttttaggga tttcactata tgaaaaggaa
     2161 aaacatgttt ttatagatat tgaggataaa ggttcaggta tttctgaaac tgaaaaagag
     2221 catattttca caagagctta tactgctgac agaaaaaaag gcaatggttt aggtttggct
     2281 atttctcaag ggcttgcaaa ctctatggga ggttcaattt atgtaaatag tagacctaat
     2341 gtaaaaacag tttttacggt aaaattgaaa agttagaaaa aagttagatt taaaagagag
     2401 aaaagataat tttattttgt atactgtttt tagaaaggag ggagtatgat gaactatatc
     2461 atagagaccc atcaattaaa gaaaatatat aaagataaag ctgttgttaa tgctgttaat
     2521 attcatgtga aaaagggaga aatttatgga tttgttggac caaacggggc aggtaaaagt
     2581 acagtaatga aaatgttgct aaatcttgtt aagccaaatt ctggagaaat agttatgttc
     2641 ggtaagaaag tggcagaaac tgattttgaa atattaaaaa agattggtac tattattgaa
     2701 aatccgtatt tatatgagaa tttgactgct aaacagaatc ttgatttaca ctgtgaatat
     2761 atgggttatt ataacaaaga acatatatca gaggtattgg aatgtgtcgg attgtcaaag
     2821 caatcaaaca agaaagtttc aaaatattct ttagggatga aacaacgtct tgcaatagct
     2881 agagcaattc ttactaaacc agaattattg attcttgatg aacctataaa tgcactcgac
     2941 ccagagggga taagagaaat gcgagaatta ttccgtaagt taaatacaga ttatggaata
     3001 actatattta tttctagtca tattctttca gaggtagaac aaattgcgga cactattgga
     3061 attattcaag atggtaaact tattaaagaa atttctatgt cagatataca taaatatcaa
     3121 acagattatg ttgaagtaga tgtagataat gtggaacttg ctggatactt gttagaaaaa
     3181 gaatttggaa taaaagactt taaaattact tcggaaagtt gtattgaaat atatgattta
     3241 cgaaaagatg taaaagaaat atccaaaata tttattcaaa atcaaattgg gataaatagc
     3301 attggacgta aacaaagttc tttagaagat tacttcttcc aaactacagg tacaggaggt
     3361 aaagaaacac tatgatacat ttaatgaaac tagagctaaa aaaagttggg ctaaaaagat
     3421 attttttatt ttcaatgctg gggattttct tatgtatgtt ttttgtcttt actggattga
     3481 atgataaatc tacttcaata tatgattatg atgttacatt taggacaatc aatttatttt
     3541 tctgttttta ctatattata ttatttgctg tgttgaatgt ggcatatata ataaatgaat
     3601 atacaaataa aacaatcttg attttattct cttatccact tgaccgtaaa aaacttattt
     3661 tatcaaagtt acttttgatt acgactctta tgatatcatc aatgatagtt ggatatatct
     3721 gttgttttac attcgttgtt gtattggata agtattttaa tttagttatt ggagattttc
     3781 atatttctat tttatcttat tggataccag gagcaattaa aagtattatt gtattttgct
     3841 cattaggtat atggacattc gttgttggaa tgataagaaa atcaatacct gttacccttg
     3901 tcagttcaat tatttttatc aatttaagac aatttatttt agctggtaca aatacaactc
     3961 aagacagttt gatttctgtt tttattatag ttggtataac tgtgattggt atatattata
     4021 tactaaatca taaagttact gaaattgact agatactgtg gctaggaagg tagttattaa
     4081 ttgtatcttc ttgggataat aatgatttgc tattatatca gctattatta atattattag
     4141 agttttaata atattgcaca accatttgaa gttgagccaa agcttgatga attaattgaa
     4201 tggtactata gtcagagtga agtatctatt aaagttatag ctgaatttca ttatagattt
     4261 gaattgatac atccatttca agatggtaat ggtcgcatag gtagatttgt tatgctaaaa
     4321 cagatgttag aaaataatct tcctataaaa attgtatctt gggatagtga ggacttgtat
     4381 agaaactcct taaattcttg tagtttaggt aattatgtcc ctttaattga atatttatca
     4441 agtttagaag attttagaga agtatataaa atgttatgga aataattgtt tgtagcaaaa
     4501 aaagtttata tataaatata tttttaacta tggtatttaa cgctaatttc ttagttattc
     4561 ttagcttgga ctatacccac tattttaact atataaaata gtggatatag tttaactatc
     4621 tctttataac tattcttatg tatcttagtt gtttcttaat atggggacag ttcataaaac
     4681 taaaagtgat ttttaatttt atcatttata atttaccatt acatcagaaa aatgcttatc
     4741 attagaattt tcataaaagg tacctatttt tttcaattaa ctaaatcaat tctattagtc
     4801 ttaatctttc gtatttcaaa ttgataatac aagaaaataa aaaataaaaa attttaaatt
     4861 ttttatttat tgcgaaaaaa ataaaaaggt gctatacttt ttgtaacata ttattcaagt
     4921 tattaagaga tagtaaacat ttatagttta atttgtagta cactagcatg atttgcagaa
     4981 caatgaatta atctatagta taatagttta atttaaagta caacgattta atctatagta
     5041 caataacttg atttgaagta caacgattta atctatagta caataacttg atttgcaata
     5101 caatgaatta atctatggta taatagttta atttgaagta caatgaatta atctatagta
     5161 taatagttta atttgaagta caacgattta atctatagta taatagttta atttgaagta
     5221 caatggttta atctatagta taatagttta atttgaagta caatggttta atctatagta
     5281 taatagttta atttgaagta caatggttta atctatagta taatagttta atttgaagta
     5341 caacgattta atctatagta caataacttg atttgcaata caatgaatta atctatagta
     5401 taagagcatg atttacagta caataattta aattgtagta caaaagtact atcaaataag
     5461 aatttctact ttaaaaatat tactaaaagt aattaaagtc cagtaattca atataatatg
     5521 gcaaaagaat agaaataagg tgagagtagt gaaagtaaag tcaaatttag atgaaatttt
     5581 atatcataag attattgaaa gtcttattcg tggtgaatac tctgtaggtc aaaaaatatt
     5641 actaaatgac ctttgtgaaa aatttgaagt aagcagaaca ccagttgtac aagcagtaaa
     5701 aatgctaaat aaagatggag tgcttactat tatgacaaat ggtaaagtgt acgtaccaga
     5761 gtatgaatat gatatggtaa aacaagtttg tgaaacgaga acactgattg aaacatatgc
     5821 tttagaaaaa atgatgcaag aagaggaaga ggtttttcaa caaaagctag atgtaataaa
     5881 aagatactct gataaatgcg aggagtacta tcgtcaagaa aaatctgtag aacttgcact
     5941 agcagatttg gaattacata aagccattgt agaaggggca aataatgaga ttttaaatga
     6001 tgtatatgtt ggtatacaag gaagatttat agtagtgaac tatttaattc gaccattaaa
     6061 aaatcgtaat tatgaaggaa cagtacaaga ccattttgaa atattaaaat tcattgaaga
     6121 cagagataca aaaaaagcag tagataaact aagaaatcat attcaaggaa ctattaaaag
     6181 attctgtgaa gatgaataat aagttttgaa gttactatat atacttatct attaagttgc
     6241 taaatgtagt ctaagtataa tctaattata gtttaaacat aatctaaata taatctaata
     6301 aatataatct aaatatagtg taaataagtc taagtatgaa ttaaatatag attaagtatg
     6361 gactaagtat agattaagta tagattaagt atgaattaag catgaattaa gcatggatta
     6421 aatatacttt aaattacaaa tattacaagg aagccagaag gcttcctaaa aaaataacct
     6481 ttataaaatt ttttatttta aatttaaaat tttttatttt aaatttaaaa taaaaaatga
     6541 aagaggtggt agggagtttg aaaaaaatta ctaaagaaag gatagaagat actatgaaaa
     6601 agctatttac gagtgaaaca tttttggaat atcaatttat aagtgattgc caaatatcac
     6661 cagatggagg atatacagca tttattgtaa aaaaagctga tatcaaagag aatggttaca
     6721 caagccaagt ttatatatta aacaataaaa ctggcgaatt aaaacaaata acgtctataa
     6781 actctgttgg agcatatgcc tgggaagatg aaaatactat cttattccct gctttgagaa
     6841 atgaaaaagt aaaagaagct gtcaaaaacg gtaagcaatg catgagttac tatgctttat
     6901 ctttaaatgg tggagaagca gaagaacttt ttagactccc tatcaaaggt ggtaaattga
     6961 atcctatagg aaaaggtttg tatgcagtta ttgattctta tgacaatgac cgacctattg
     7021 tagagggatt gccagaagaa gaacaacaga aaaaaataaa tgcttacaac aaaagacatt
     7081 atgaacattt caaagaaatt ccttatgctg tcaatggaga gggatatatt agcagaaaaa
     7141 gaaaacgcct atatatatac gacagtaata taaatgagtt gaaggcaatt acagcaccta
     7201 tgtttaatgt tgtaggtatg aaaataagtg atggaaaaat cttatatata gggcaagagt
     7261 ttaaagatgt aaaaggtttg aaaaatgggg tctatgtatt tgatacaaac acaaacacaa
     7321 atgtctgtat attagaaaaa gataagtata ttataaaagg ttttgaatta tatcaaaatc
     7381 aagtgatact aaacctaact gatgctttat cttatggaaa tggagaaaat ggagattttt
     7441 atactattga tattgatacg aaagaaatga aacttctttc agggcatcaa catcattgta
     7501 ttggaaatac agtaacatct gatgttaaaa tgggtgctgg tcagacaaca aaggtagatg
     7561 gagaatatat ttattacact tctacagtag atatggactg cattattgaa agaatacata
     7621 ttccaacagg aaaacaggaa aaagtaacac agacaggttc agttgatttt atagatgtaa
     7681 aagatggcaa tattgtatgt gtgggttgtt taggaaatgg attaccagaa gtttatacag
     7741 tagagaatgg aacattgtgt aagaaaacac atttaaatga ccatatttta gaggaatata
     7801 aaatttctgt gccagaatac atagagtcaa aaggaagttc taaatgggaa atacaaggat
     7861 acgtatataa accagtagat tatgaggtgg ggaaaaaata tccagctgta ttggcgattc
     7921 atggaggacc aagattgaca tatggaccat attttatgca tgagatacag gtatttacaa
     7981 gtgcaggtta ctttgtattc ttctgtaacc caagggggtc tgaaggtcgt ggcaatgctt
     8041 ttgcagatat taggaaacag tttggagata ttgattatat agattttatg gaatttacag
     8101 atactgtact tgaaaaatat acagacattg ataaaacaaa attggctgtt gaaggtggaa
     8161 gttatggtgg atttatgacg aattggataa ttggtcatac aaaccgtttt gctgttgctt
     8221 gtgctcagcg ttctattgca aactggagtg gcatgcaggg tacaacagac attggttatt
     8281 atttctgcaa aggacaaaca ggtgcttctc atatggaaaa ccacgagctt caatggaaac
     8341 agtcacctct tgcttatgct gataaatgtg ttacaccgac tttattttta catggtgaaa
     8401 aagactatag atgctatatg caagaagcat tccagatgtt ttcagcattg aaaattcatg
     8461 ggtgtcctac aaaactttgt ctatttgaag gagaaaacca tgaactgtct cgttctggta
     8521 gaccaaaaca aaggctacaa agattagttg aaatgctaga ttggttttcg gtatatataa
     8581 aaaaagataa cataggacag tagaaaggag aatataaaaa tggaaaaaat aaagattgaa
     8641 agttcagata tttttgaata tatattccct catgatattt cttgttcacc tgatggaaag
     8701 catattgctt atattatatc aaatatcaac gaggaaaaag actgctatga acatgactta
     8761 tatgtgatgg acatcaaaac agaaaaacaa atacatatga ctcaaacaaa agatgtaaca
     8821 tcatttagtt ggatttctaa tacagaacta ctttttacat ctaaaagaag taagccaaaa
     8881 gcaggtacaa cagattttta cactatttct atagaaggag gagaagcaaa aaaagcattt
     8941 tctattccaa aagcttgtag cgtacctgta tcacttggaa ataaattgtg gttactgaca
     9001 acaaaaaatc caacggattc taaaaaatca gaaccagata gggcagtaga gggtgtagat
     9061 tattggacat ttacagataa accttttata agagatggag aaaatttttc tcaaagaaga
     9121 cgtgtaacat tagaattata tcaagaaggt gaaaatataa caaaagccat tacaccaaaa
     9181 ttttgtgaag tagcaggtgt agacgtttct tttgataaaa acagaatttt atatactggt
     9241 cagatttatg aagattgtgc aactcctttt tctggacttt gggagtatca tatagacagt
     9301 ggtgaaacca aagaacttgt accacaagga aagtatcaaa taagtttggc aaaatatatt
     9361 ggcaaagata aagtaatgtt gcaagcttca acattagacc gttctattac acagaatcat
     9421 gatattttta tacttgattt gagtactagt gaaataaata tgattgctag tccagatggt
     9481 atgtatgcta cattactgga tgtagatgca gtatatggtg gtggacgtag taataaagtt
     9541 ataggagata aatttattgg tgcaagaatt tgtagaacta tgacagaatt taatgagttt
     9601 gatacaaaga caggtaatat acgtatcatc acaaaagtag atgcttttac atcttttgat
     9661 atttacgaca acaccatgta cacagtaatg ttgaaagatt atgagttagc agaaatatat
     9721 agcattgata tgactacagg tacaatgaaa aagatgactg ctttttctaa accatattta
     9781 gatactcata aggtttcatt acctgaaaaa ttgacgtttg tagcaaaaaa taaagaagaa
     9841 gttgatggtt ttgttatacc acctatagat gctaaagaag gcgaaaaata tcctgctgta
     9901 ttgttcattc atggtgggcc taaatgggca tatggctata tgtttacaca cttgaagcag
     9961 tgtgtaacat caaagggaat gtatgtgatt tattgtaacc ctcatggtgg tgacggttat
    10021 ggtgaaaaat tcttagaaat ggtagaaaga tgggggtatg ttgactatga gcatcttatg
    10081 gaatttgtag atacttgtat tgaaaaatat cctgggattg atgcagaccg cttaggggtt
    10141 gcagggggaa gttacggtgg ttatatgaca aactggataa ttggtcatac agaccgtttc
    10201 aaagcagcag tttctcaaag aggtattagt aacttgatta cagcttcttt aattattgac
    10261 tttggggata gaattatgaa gcagacttgt ggagataaga cgccttggaa tcatgaggag
    10321 gttctttgga atcattcacc tattaaatat gtgaaaaatg ttaagacacc aacattgttc
    10381 ttacatagtg atagggatta tagatgtttt atgggggata ctttccaaat gtttacagca
    10441 ttaaaacaac ttggtgtaga tacagaaatg tatttgtttc acggagatac acatggattg
    10501 tctagaaatg gaagaccatc taatagaatt gcacgagcaa atgctattgt agattggttt
    10561 gaaagatatt tataataagg gggttattct atgagtgata tgttattatg gtttagtgtc
    10621 gtattagttt tatttgctat tggggattta attgcaagca aaacaaaagc aaaagtatca
    10681 gctgtatttg ttacactact tttatttttg attctatttg tcacaaaagc aataccagct
    10741 gatattattg aaaaagcagg tatgaccgca gcagctagtt ggagtgttcc aatgattatg
    10801 tttagtatgg gaacaatgtt gaatgttaaa caatttatag acgaatggag aacagtattg
    10861 acagcatggc ttggaattgt agcagttata gtctgtgtct cattatgtat tcctttgttt
    10921 ggaaaatcaa cagtattgac aagcatacca gttataaatg gagctttacc tgctactact
    10981 attatgacac aagcagcact agaaaaagga ctgacacttg cagcagctac agcaacagtt
    11041 gtatttgcaa ttcagaagtt tattggtaca ccaatagctt caagagcagc gttacaagag
    11101 gcaaaccgtc ttttagtaga atatcatgaa gcaaaatcaa aaggcattga tttagcaaat
    11161 gttgatactg ataagaaaga agcagagaat acaggcacaa aagtaaaaca agctttctgt
    11221 gaaaaatacg ataaatatta ttctacaaat gtttgtatat tttttatagc actattctct
    11281 tatctagggt atgaactttc agagattatt catgtaaatt attctattgt atgtcttgtt
    11341 gttggtgtta ttgtaacacg tattggtatt gtgccaaaag acattttgga aaaaggaaaa
    11401 atcaagggat ttatcaacat ggttgtgttt gcagctgtta ttccttcttt agcaaaagtt
    11461 tctttgacag atttaattag tctttttgta ccaattgtag gtatgtttgc agcttctatc
    11521 attggtatat tccttatgat gaaggtgtta ccaggttgga aaattatcgg ttctaaacct
    11581 cttgcttttg gagtagggtt ttgtcagatg ttgggattcc caactacata tttaatttca
    11641 aatgaagtgt gtaatgctgt tggagaaacg gaagaagaaa gagcatattt gatgtctaag
    11701 attatgccta agctggtagt tggtggtatg gcttgtatga tttctattgt ggtagctggt
    11761 cttatggtac caatgttgta gataggtttc aaagttaaaa aagtggtgtt aatttatagg
    11821 agaagctaaa aagtagtatt aatttataaa taaagctaga aagtcagtat taatttataa
    11881 acgaatttta tattagttaa tttattataa gaatattttc tttttagcat tataatcttg
    11941 attttatcaa gaaacagatt ttttatttgc tattctaata gttacagttt atttttattt
    12001 tctaaaacaa aactttaact tgatttatct ataaataggg tatttaataa tatttttgga
    12061 aaatctttag aaagaattaa aaagaggaga aaaaagggag tgccacaaag tgaacttttt
    12121 agttctaagg cactcttttt tgtacgaaat cgaatatatt ttcaacgttt taaaagtgag
    12181 aaagagattt atctctagtt tgagatagcc aattttaatt attaaaatta ttttttgttt
    12241 tatttatcaa agagtattcg tgttttagaa gttagtattt tttattttat atatacaagg
    12301 ttttccgttt ctaatgtttt cttttttaaa ataattaggg tattcaatta tggtaaaagg
    12361 tggatggtat tttgcagtga tattatttaa agcacagtat tgaatgttga aatcctcaca
    12421 ttttagagta ttatcttttg taatcaaaaa aatcttctat acttatagca aggttatttc
    12481 tgcaaatatt ccatgcatca taatatctaa atttaaattt ttttaatata gagtttacct
    12541 ctagtctaca ctcttgaata actctttcct ctatccaaat tcttataaat tcatcccatt
    12601 tattactatt tatttattac tatctaaatt ttttagtatg tttgtaatta gaaatggatt
    12661 tattccttta tgttttttat aaatagttta taacttaatt tatcattaaa caaatcattc
    12721 atacaggatt actttttctt ttatatattc aattcttact tttaataaat atttaataca
    12781 tcctatctta tgtggtttta aaaagtgttt atagctatca acaatctcta atatttcatt
    12841 catatttatt ttgtcatagt aatattttac atcttttata ttgacaaaaa agtgctctaa
    12901 gtgtatagtg tgtatatgat aacatcacac tgaaagtgat aaaaaggggg tgataaaaaa
    12961 tgaaagtgct catttctaac acatcagata agccattata ccaacaaatt aaagagcaaa
    13021 ttaaagaagc aatatttact gaagaactga aagaagggga tgcaatgccc tccataagaa
    13081 attttgctaa tgatttaaaa gttagtattt tgactattag acgagtgtat gaagaacttg
    13141 aaaatgaagg ctttcttata cgccaagttg gaataggaac atttatttca actggaaatt
    13201 tagaaatact aagagactca aagagacgta tagttgaaca aaaaatggca gatatgatta
    13261 aggatgcaaa agcactagga attacacaga tagagttaca agaaatgatg gatattctat
    13321 atcaggagga ttaatatgga aaatatttta gaagtttata acttaaataa gacttatacc
    13381 gatttttcat tatctaatat aagctttgca ttaccagaag attgtataac tggatttata
    13441 ggtgttaatg gagcaggaaa aacaacaaca atccgttcga tattggatgt cgtaaagcgt
    13501 gatagtggaa aaataaaaat ctttggtaaa gatttcgatg gaaatgagaa ggaattaaaa
    13561 aatcgaattg gagttgtatt tgatgattca tatttctatg aggagttgtc aatggcagaa
    13621 atgaaaagta ttattgcacc ttcatatgat aattggtgtg aagaagatta tcaacaaaat
    13681 atgaagcgtt ttaatcttaa cccaaaacaa aagattgata cactttcaaa aggaatgaaa
    13741 atgaaatttg ctttagcatt agcattatcg cataaagctg agtttttaat tatggatgaa
    13801 cctacaagtg gtttagaccc actaatccgt agtcagatac ttgacatact aacaggatat
    13861 atgaaaaaat gtggtcgtgg tgttttcttt tccactcata taacatctga tttagacaaa
    13921 atagcagata tgattgttat gattgacaat ggacgtatta tattagaacg tgaaaaagat
    13981 actctattgg acgaacatag aaaagtaaaa ggggatattc aatttctaaa tgatgaaacc
    14041 aaaaaattat ttttaaattt agaaattaca ggttatggtt ttatagggat tacctcaaaa
    14101 attaatgaag tgcaaaaaaa tatgccagat attttaatag agcgtcctac aattgaagat
    14161 attatgcttg catatattga aaggagagag taattatgtt gattcattta gttaaaaaag
    14221 atattctgat tgtaaaaaaa tatgtattgt tgatattatt tattgcaata ggaatcccat
    14281 tatttatatt atggcgttta cctccatttg cacaaatatt gggatttgta ctatccatta
    14341 tattttcaga atttatgctg tgccagtatc tattattaaa ggagagtcaa tattcaaaag
    14401 catctgtatt actttgttca actccttatc ctagacgtgg cttagttcaa tctaagtatg
    14461 ttttatttgc aatggtattt atctattgta cattagttta ctggattgaa aatttactta
    14521 ttccacaaat aggaattttt gacttaacat atattttgat tgttttatta ataagttcta
    14581 ttatttatgg agtttatatg cctattcaat ataaattagg atatgaaaca acaaaattct
    14641 ttttcgtggt gataatcatg gcttcatcat ttgtattacc attaactata gctcacagca
    14701 attttgaaat tccatttata tatcaatatc catccatgat agtgaatatt gtattgttcc
    14761 ttttaagttt aattatactg ttagcttcaa tgtttatttc tattaaaatt tttagtaata
    14821 aggaacttgt ataaggtaag ggggactttt atatgccaca tttaccagat tgggctgttt
    14881 tactttgtat cttacttcca atagtatata aagcttgtca gatatttaaa agtaaaaaat
    14941 agagtacata tttatattgc catttttatt gagtaaagtt agatggtatg aatttaaaag
    15001 gttacttgaa aataaagtta cttggtgcgg gagagtaaca tcataatatt atagattata
    15061 tgtttcttgt gaatcaattt gtatttttta atagataata tccagtaatt ttattttcca
    15121 ttgattattt ttcaattatg agtatgattg tgtgtattgt ataccatctt ttaaggtgtt
    15181 tttaaaaaat tatatcgtca aaatataaat ctaaggaatc ctataaataa agcttttcaa
    15241 ttttagaaaa ctaataaaaa gtaggaagtt aataaaaaga agctgtctca aaatagagat
    15301 aagcttcttt ttcattgctg aaatgacgaa aatataattg atttaatata aaaaagagtg
    15361 ctttatgaac tatttatttt gaacagtaga tacacttgca ctcaatttag ttactcctaa
    15421 gctttatgaa ctaaaagttt attttgaagc ttatttttat taaaagagat tttatttttc
    15481 taaataatca tctatataca gtattgcttt tcttttattt attcataatt tattttctta
    15541 ttaaagtttt tctatattca tattttctat attactttac ttttaatttt atacgaatta
    15601 tcaaaaataa aatagttatt agaaaaaaat aaaagtaatt gcaaagcttg caattactta
    15661 cttctatatt aattactata ccataaaata acaaaaaaat caagtcgagt aatccttcaa
    15721 cttaagtgat atactaggta ttaataattt ttaattaata aaatataact agaggaaaat
    15781 ctacattttc tcaatttctt taattaaatt gacctctaat taagtaatta taaggagaaa
    15841 aattatgaat ttagcaaagg gattagatgt tttaaaaatt tcatcaaatg tattcggtga
    15901 agataaagtt atgtatattc ctgtaatcta cacagaagat gatgcaacac ttattgacac
    15961 aggtcttccg ggtcaaggtg atttaataat tgatgctctt aataaaagta acacgagctt
    16021 tgataggtta aaaaatataa taattactca tcatgatata gaccatatag gaaacataaa
    16081 ttatctaaga gaaaaatcta agaataatat caaagtatat gcatacaaaa gtgaagtcag
    16141 ctatataaca ggagaagaaa ctccttttaa gctttatatg ttggaacaaa tggtagataa
    16201 aattgatgat aagatgctta gtatgctaaa tgttatggga cttggattta aatcatcata
    16261 tactaaagta gatgtgtcat tagataacca tgaaaaattg gatctaggtg aggaaataga
    16321 agttatacat acaggaggtc acactagagg tcacatatgt ctttatttaa aagagtctaa
    16381 agtacttatt gctggagatt tgttacaggt agaaaatgga gaacttaagc ctgttgatgt
    16441 aatgcacagc aacaaacaag agttaaaaga tgctattaaa aatataagta attatgatat
    16501 agaaacgata gtttttagtc atggtggatt atatcaaaga aacataattg aaacattgaa
    16561 aaacctaatt attgagtagt actatatgat ttacaataat ttcttaaatt acttaaaatt
    16621 atatctaaag atgtagaatc aaaattaaat ataagtaata agaattttgc tttaaaatta
    16681 tatttaagtg ttaagggtga tacgtagtat tacaagtatt ttagaatata gttttttata
    16741 gtaattttaa ggttctacaa tacttcagtt gaaaaatatt taacagcata gtataatggg
    16801 aaagaaaata ctttaaataa actttagtat acaaagtgaa gaaaaatatt taaattatat
    16861 ataatattgt agagtgatgt aaaatattta agttatatat cataatgcag agtgatgtaa
    16921 aatatttaag ttatatatca taatacagag tgaagaaaaa tatttagata atgtaccata
    16981 atacaaggtg agtaaaaata tttaaatcat gtatcataat gcaaagcgaa gaaaaatatt
    17041 taaataatgt accataatgc agagtgagta aaaatattta aataatgtgt tataatacaa
    17101 agcgaataag attatttaaa gcatgtgtta taatacaaag cgaataagat tatttaaagc
    17161 atgtattata atataaagtg agtaaaaata tttaaatcat gtatcataat acaaagtaaa
    17221 gaagattatt taaaccatat atcataatgc aaagtgaaga aaaatgttta aattatgtat
    17281 cataatgtag agtgagtaaa aatatttaaa taatatatca taatgtagag tgagtaaaaa
    17341 tatttaaatc atgtatcata atgcaaagtg aagaaaaatg tttaaattat gtattataat
    17401 ataagcagag tgaagaaaaa atttaaatca tgcatcataa tataagcaga gtgaagaaaa
    17461 atatttaaat aatatatcat aatgtagagt gaagaaaaaa tttaaatcat gtatcataat
    17521 ataagcagag tgaagaaaaa tatttaaata atatatcata atgtagagtg aagaaaaatg
    17581 tttaaattat gtatcataat ataagcagag taagtaaaaa tatttaaatc atgtatcata
    17641 atgcaaagta aagaaaatca tttaaattat atatcataaa aataatatga aatattgaac
    17701 actaataata ttagaggctt tactatttta attgataggt tatattattt ataacattaa
    17761 aaatacaatt tacataaaat agacatatga aaaataaaaa attatataat aattatggga
    17821 atgaggttct cccttggatg ataatatcct aaactgccaa tgagctgatg acttctatga
    17881 tatcatagat gccaccagct ttttttgttg tttaaatcga taaaatggag gtaaattact
    17941 tactaaattt ttatttttta aatttgaaga aatatttaat taatagaaaa aatagtagat
    18001 tatatgttaa ttattttatt aagaatgggc taagagtata cctatatcct atcaatttaa
    18061 aaaacaatta tgatagtcat tacattgact acagttgatg caataaaact ttcaaaaaat
    18121 cttatgatgc aaatagaaag gaattaaaat gatagaaaaa tttaaaactt taatatggat
    18181 taaaataata ataagaatta aaagcgttta taaaacatat ggtggactat ttttgttagg
    18241 actcataggt ataccagttg gtgcaattat aggtcttata gacaccatat ttggaacggt
    18301 tcttctaaaa gttacagata ttcgagaaac atatccaatg tatctgatac catttttagc
    18361 agtagtagga gttgttattg cttattgcta ttttaaattt ggaggaaaaa gtagtaaagg
    18421 aatgaatcta atatttgagg tagggcacgg agaagaagaa attattcctt taagattggt
    18481 tccatttata atatcaggta catggttaac ccatttattt ggtggtagtg caggacgaga
    18541 aggagttgct gttcagattg gtgcaacttt ttcacattgg gtaggtaaaa ggttgcctat
    18601 aaaaaatgct tctagtattt ttctagtaac tggtatggca gctggttttg caggattatt
    18661 tgagacacca atagcagcaa tactatttgc tatggaggtt ttggtagctg gttcactgga
    18721 gtatcaatcg ctttttcctg cgtttactgc ttcttttaca gcaagttcag tatcaaaagc
    18781 tttagggtta gagaaatttt cttttgcact ttcttctaaa gttgtatttg acttgtcaat
    18841 attttggaag cttattgttt taggaattat ttttggaatg gttggtggag catttgcatg
    18901 gtgtctgaaa ttgtcaaaaa gaaaaatagg gaatagatta aaaaatccta tgataaggat
    18961 tgctattatt ggagtatgtc ttagtgtatt attcctttta ttttataaag gaagatattc
    19021 aggcttaggg acaaatttaa ttcaaaatag tttctatggt ggagaaattt attcatttga
    19081 ctggctgtta aagtttatac ttacaatact gactttgtca gcaggttttc aaggaggaga
    19141 ggttacacct ttgttttcca ttggagctag tcttggtgta ttgttagcag gattttttaa
    19201 tttgccaatt gaattagttg cagcgcttgg ctatgctagt gtctttggta gtgctacaaa
    19261 tacttttttt gcacctgtat ttataggggc agaagttttt gggtacagct atttacctta
    19321 tttctttgta gtatgcgcta tttcatatat atttaatatg gataaatcta tttattcact
    19381 acaaaaaatt tcaacaaaac aataaataaa acaacataat gtatgattag aagagaaaga
    19441 atattagaga aaggataggg taggaatatg ttgacaagtt tagctttgat ttttttatta
    19501 ggaatggcct cgggaggtat ttttaagagg ataaagttac ctaacttatt gggaatgtta
    19561 cttacaggaa ttatattagg tccatatgtt ttaaatttga ttgataattc aatactagat
    19621 atttcttctg accttagaaa gattgcattg attattatat taacaagggc tggattatct
    19681 ttagatataa acgatttgaa gaaagtggga agacctgctg tacttatgtg ctttattcca
    19741 gctacttttg aaattatcgg aatgatagtt ttagcaccaa aattactagg cgtttctata
    19801 ttggaagcag cagtcatggg tgcagtagta ggagcagttt ctcccgcaat tattgtacct
    19861 aaaatgctta aattaatgga agaaggttat ggtacagaaa aaagtattcc acagatgctt
    19921 ttagcaggaa cttctataga cgatattttc gtaattgtga tgtttacagt attcacagga
    19981 ttggcacaag gaaatagtat atcagctatt agttttttac aaattccagt atcaattata
    20041 ttaggtgtaa tagttggagc agtgattgga atctgtttag cagtattttt taagaaggtt
    20101 catatgagag attctgctaa aggggtgttg cttttaagta tctcattttt aatgataagt
    20161 ttagagactg ctttagaggg tattgtgcca ttttctggat tattagcagt tatgagtatt
    20221 gggattttcc ttcagataaa atatcgtgta gttgcaagaa gattgtccat aaagtattca
    20281 aaactatggg ttggcgctga aattctcttg tttgttttgg taggggcaac agtagatata
    20341 agttatgcat ttaaagcagg aattggagct gtaattttaa tatttggagt tcttttattc
    20401 cgtatggtag gagtattctt ctgccttatt aagacaaatt tgacaataaa ggaaaggttg
    20461 ttctgtatga ttggctatat tccaaaggct acagtacagg cagcaatagg aggtgtacca
    20521 cttgcaatgg ggatggcatc tggacaactt attttgacgt tagcagttct agctatactt
    20581 ataactgcac ctcttggagc ttttggaatt gatgtaactt ataaaaaatt attaacttct
    20641 gtaaaaggcg agagtaagta aaaataaaga ttattttaac tggtaagtta tattttggaa
    20701 aaggattata ctattgaata caatataaaa aaatcatttg ggagattaag aaggtagaag
    20761 ttaagaacag attttaaggt atgttatgat tattagaatt gattttgtga aattattatt
    20821 gtaatattta attatataga taaagaagcg gagtgataac tatgtgttta aaaaaattat
    20881 caaaattaga gttagttatt atgaaattta tttggaattt agatataaaa accaattcat
    20941 atgagattat tgattatatg aaagaagaac ataatttacc agaaaaagta gctttaaaaa
    21001 ctttatcaaa actatcaaag aaaagattct tatatgttca agaaacaggc aagtgtatgt
    21061 attatacagt tgcaataaaa gaaaaggcat atttagagtt tatatcaaga aatgtgcaaa
    21121 atcttttgaa gaataatttt ataaggaatt tattagtatc atttcacgaa gaggagctaa
    21181 cagaggaaaa gataaagtcg ttagaaaact gggtagtaaa ttgggaagaa gcttatgtat
    21241 aaatgttatt atttttatta caatttagat aattttggtt ttgtaagctc tgcaactatt
    21301 tttagatggt tgcagagttt atttttattt tttattccct taagcaatac ttaaaagtaa
    21361 acgcatttat atttactaac ttcaattact tctaatactt aaattacttt ttaaaaatat
    21421 tttgatatgt catctctata gtaatctaga acttgtttct attctttata taaagttttt
    21481 atgaatgata tatataatat tcgttcattt gattaaaaat aacaaaatat taaataattc
    21541 tactctgata gtttgttaaa aaaataataa aaaatattaa taaacaaaaa aaattatctt
    21601 aagagaggag aatgttctaa aatataaaaa ggtttctaga tttcataaaa gatactattt
    21661 tagtcttgaa aatatttagt ttgaaaagat tttaatttaa tgattgatta agttaaaaat
    21721 gtgtatgtaa taaattttat tttatttatt gactaaatta taaagtttac ataattattt
    21781 aataattatg taattgttac ttgaaaattg atctatttta aa
//
LOCUS       DAEPXW010000067        21681 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.068, whole genome shotgun sequence.
ACCESSION   DAEPXW010000067 DAEPXW010000000
VERSION     DAEPXW010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21681
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.068"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            8..579
                     /locus_tag="KRM55_002487"
                     /pseudo
     CDS             8..579
                     /locus_tag="KRM55_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
     gene            complement(1591..2253)
                     /locus_tag="KRM55_002488"
     CDS             complement(1591..2253)
                     /locus_tag="KRM55_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594721.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(2270..4825)
                     /locus_tag="KRM55_002489"
     CDS             complement(2270..4825)
                     /locus_tag="KRM55_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1594722.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNQLFSINKEFKIVGVMEKPKGYYDVVWQYKAVTYGNDETNNIIPNDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKSDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLFRLMGAKKRNVRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEALYSEAGLNPKLYINNEIVIKAILVGIISVFISCIIPIFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIHKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDDYIDEKLNDFVEEGSLD
                     DIKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNIGDIITVKIPVEENNTIVYKEMK
                     VRVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLENPYDEIVNN
                     EIQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNL
                     LIRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAY
                     INYGIENFMSFTFPIKESLLFFAISVFVCLIAVVVSNRDFESMNIIEGIKENE"
     gene            complement(5058..5252)
                     /locus_tag="KRM55_002490"
     CDS             complement(5058..5252)
                     /locus_tag="KRM55_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBH1594723.1"
                     /translation="MRKYKAILLTLIISIIAIIGFIIYNNYFRKWNEAEKYIDKYMTY
                     QGVSGDDIERITKEKYTKEN"
     gene            complement(5264..5443)
                     /locus_tag="KRM55_002491"
     CDS             complement(5264..5443)
                     /locus_tag="KRM55_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594724.1"
                     /translation="MIHVEISEKEFFRKIEEVFDKGEGNIEVDNLGDIKIQVKKFDDK
                     TKSLELKLIKEFKLK"
     gene            complement(5448..5705)
                     /locus_tag="KRM55_002492"
     CDS             complement(5448..5705)
                     /locus_tag="KRM55_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594725.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLENLEYTKEQSSQVLH
                     YSMTKDKKGTKEILSIQCVKDFSYNEKLSEGDKFIMAIYNI"
     gene            complement(5678..5845)
                     /locus_tag="KRM55_002493"
     CDS             complement(5678..5845)
                     /locus_tag="KRM55_002493"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594726.1"
                     /translation="MKIKKITITMVIAISLTLGLITGCTNKVSDTNEKIYTIEQISSI
                     KKTCQRKYQNQ"
     gene            complement(5967..7360)
                     /locus_tag="KRM55_002494"
                     /pseudo
     CDS             complement(5967..7360)
                     /locus_tag="KRM55_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            complement(7354..8029)
                     /locus_tag="KRM55_002495"
                     /pseudo
     CDS             complement(7354..8029)
                     /locus_tag="KRM55_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(8669..10279)
                     /locus_tag="KRM55_002496"
     CDS             complement(8669..10279)
                     /locus_tag="KRM55_002496"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594727.1"
                     /translation="MYIEELKQNLNNKIGDIINIYLKIYWNRISNRGEKNLYNIYFNR
                     EIKRVLYNKYLENINIDKRDISVVYDCIINDLNSEIDKRIRNSNINELMAILYGIACF
                     QAEFHGRVFITLNNNTSNFSNILHIEKDILRYIERNLKKRFIVDSISATDKSSIQYLI
                     EKCMHFSSDSDNQNNFGVKLFTDVYMMSLIITNLIAEKNMLLSGLCDDISVWINDYMI
                     YNNLDRYYDNEIIYKEYIEDLNFDIRDYDSKIIEKLKNNFFKSYGFRIETIERFLNST
                     NKTIKDTELVHLVEEKTLVKAFCDDSGADIEEIRFLIKYLTITKSIEYDKLKSMENYS
                     NRILEKAFININNCNISIYMFSYIILLHSYEILIRKLVYNLLPKCKKINSKIIEREIK
                     NNLVIDCSNILKKYTNKIIINAHKVYINNEKIITLSNEIDLIAVVTKKLFIIECKDIY
                     YKFTPYGFKCDINKTYSFISKMEKKYKSVLENKQNLEIKFGCEIEEIQPIIVFKTYNM
                     AINSKLNNNRIKIINFNGLEKLIRDTKN"
     gene            complement(10366..11493)
                     /locus_tag="KRM55_002497"
     CDS             complement(10366..11493)
                     /locus_tag="KRM55_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBH1594728.1"
                     /translation="MTIPKLEPSDRKREFDKYTSQQINKVVYNYLFEKNMSNRKIEGE
                     ILNLSSKQNKGYQAMSILHHLGINKNHKGVFMGYTIDKAIEVLKEDEIYFKQIINILL
                     ESKNINKYPIIVDSWELLDEKIALKTIDKSTLKHNRTGVPIEIRHFFEINNLGKNEKK
                     NVNFRYDDNYYSAVIEMDKLENPRSRIIWKSKFRDLLRNIFPKYYEKFLEDEIEGKTN
                     LPKIRFVKFDSNNFDIEFIFTSEIEDDVLEEISQDNPLDIDTINIELETEIRKEGKVK
                     YVYGKQYERNPKNRIEAIKYHGTKCVVCGFDFEKTYGNRGKGYIEIHHIRPLSSVGKE
                     SNINPKTDLVPICSNCHRMIHRKKDSVLSIDELKQLIKDKK"
     gene            complement(11739..12014)
                     /locus_tag="KRM55_002498"
     CDS             complement(11739..12014)
                     /locus_tag="KRM55_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594729.1"
                     /translation="MYGEIIEIYFDYWINEHMYRDILEKDKYYIESWKEIITTNELLE
                     KSLLEEDRRYVLMELNDLFNSLIEFERELSYKFGFKAGVKFIIELLK"
     gene            complement(12262..13588)
                     /locus_tag="KRM55_002499"
                     /pseudo
     CDS             complement(12262..13588)
                     /locus_tag="KRM55_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            complement(13601..14344)
                     /locus_tag="KRM55_002500"
     CDS             complement(13601..14344)
                     /locus_tag="KRM55_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594730.1"
                     /translation="MSNLGWIKLHRKIKESPLYKDCNSKQRDILINLLLSVNHKPNKW
                     VYGGKEYEVKSGQLITSLESIANMCSKDVSIQNVRTALKKFERYGFLTNKSTNKNRLI
                     TIENWELYQSNEENQQTNQHAINKQLTTNKNINNEKSKIYSEIIEKFNITCTELSKVK
                     KLTEARKKVINARIKEYDKETVLEIIHIVSKTSFLNGSNEKGWKASFDWIMSPNNFLK
                     ILEGNYQDKSINVKVGADAYSPDDSQLKW"
     gene            complement(14365..14673)
                     /locus_tag="KRM55_002501"
     CDS             complement(14365..14673)
                     /locus_tag="KRM55_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594731.1"
                     /translation="MADTNNLEVLKTLQATLNILVKQEAQEKAKGYKEIQTYRRDKAQ
                     LITCKEASKIYPIGESKFRQLCHSKNKGFPCIWIDNRVYIIKNKLDDWFIENANGIKL
                     "
     gene            complement(14677..14871)
                     /locus_tag="KRM55_002502"
     CDS             complement(14677..14871)
                     /locus_tag="KRM55_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003450825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594732.1"
                     /translation="MKLKLKRIEKGIKQYELAQKVGISRYYLSSLERGKSKNPSNMLM
                     LKLAQELDTSVEELFFDKGE"
     gene            15013..15873
                     /locus_tag="KRM55_002503"
     CDS             15013..15873
                     /locus_tag="KRM55_002503"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594733.1"
                     /translation="MINNTIGEKIKQYRKSLNMSRDELANKIGCSVHAIAKYEQNQRK
                     PNLDIIKKISTALSIPINRLIIEENDLDISTNNYTNLKEFDSVVKTFDNYSAKLIGNN
                     ISKFRNINNISIKELSEKINCSENEIINYENGTKMPRIEILKKIALATYTNIEDLFGF
                     PLEEIKIDNQTILYRNPQTGYIINDFLIDFINKDIDIDNTPVSHYIDKSEFDLVIHIL
                     ENYGYDINTDYKTKFEITDNVDTIKPINLNFSDFKNFSKNLNWVINGLVENFIQENSN
                     GLIENEDEEY"
     gene            15962..16714
                     /locus_tag="KRM55_002504"
     CDS             15962..16714
                     /locus_tag="KRM55_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1594734.1"
                     /translation="MNKSYIPKYTYKFPTNLPHGDKKYTLTYIRRMISEFVYDMGKLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNSN"
     gene            16704..17334
                     /locus_tag="KRM55_002505"
                     /pseudo
     CDS             16704..17334
                     /locus_tag="KRM55_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17450..17680)
                     /locus_tag="KRM55_002506"
     CDS             complement(17450..17680)
                     /locus_tag="KRM55_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594735.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVADMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(17686..18165)
                     /locus_tag="KRM55_002507"
     CDS             complement(17686..18165)
                     /locus_tag="KRM55_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HBH1594736.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKTQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFNSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRYEEEV"
     gene            complement(18165..18380)
                     /locus_tag="KRM55_002508"
     CDS             complement(18165..18380)
                     /locus_tag="KRM55_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HBH1594737.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            complement(18718..19857)
                     /locus_tag="KRM55_002509"
     CDS             complement(18718..19857)
                     /locus_tag="KRM55_002509"
                     /inference="COORDINATES: protein motif:HMM:NF038233.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="retron St85 family RNA-directed DNA polymerase"
                     /protein_id="HBH1594738.1"
                     /translation="MHLKYSNLMTLESLNLPKIYNLESFSTEIGLSTTILYLLSQKQD
                     KFYHQVIIPKTKSGNRTLSIPSISMKIVQKWIKVKILDNIPVSNCAMAFRKGTNYGIK
                     MNAELHKYNTYILKLDLKDFFNNIEREKVFYLFREIGYNNYISNILSNICTFNEVLPQ
                     GGVTSPSISNLICKRLDRRLENLASKRDITYTRYADDLIFSCNDEVLLIKIKNVILDI
                     LKSEGMEINKLKTKFIRPGSRKKITGLHIDKNKVVVPRDTKRRVRAMIHYAITKEDYS
                     KLDEIKGYISFISSIEGNYISKIKSYINKIVNNGQCRLFGPIVESYNKNKIFKNLELV
                     SCIEEMDWVITKGAFYNREKYELKEVIEKSTEYGEDNINGETSPF"
     gene            complement(20044..20925)
                     /locus_tag="KRM55_002510"
     CDS             complement(20044..20925)
                     /locus_tag="KRM55_002510"
                     /inference="COORDINATES: protein motif:HMM:NF038232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="retron St85 family effector protein"
                     /protein_id="HBH1594739.1"
                     /translation="MKIKNSYLNSVNKIYTDIYKNINKEYIDVFLCGGVSTNKSCIRD
                     MVRIELENNKIRVLYPEDLFMDILSKNKSMDLLSLENFLADNSDVICIIPESPGSLVE
                     LGAFTNNKRTLENLFVVINEKYKTQKSFITTGPIKYIMNEKGSNRITYYNEDLNALIT
                     LLKFKFRKFIRMSKNKTMDVDTIIGQYYFMQLVIYFTKHISNKDLKKLINYIYTENKY
                     EKEKFNMIFSSSLKLLYKNRHIKRDIISGKISLTDKGNIYVEGMIYNLNIKNRGKLYD
                     SIRYGILYSELYGKIPL"
     gene            complement(21270..21619)
                     /gene="ssrA"
                     /locus_tag="KRM55_002511"
     tmRNA           complement(21270..21619)
                     /gene="ssrA"
                     /locus_tag="KRM55_002511"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         7398 a         3290 c         2096 g         8897 t
ORIGIN      
        1 taattaattg aaaaaactag taaaaatatt aataaatatt atttgtatta ttacgctaac
       61 tttctctagc ctttcgattt acataaaatt atctgaatat aaaaagctga tgaagtatat
      121 acggaactca gagaaaacac tatcaataat agcaaacatc aagaacttta tgataaaaat
      181 aatgattata gattctggct taaaataaac aacgtaaata tagactatcc tgtagtacaa
      241 ggatataaca atgatttcta cctaactcat gatttttata aaaattatct tcctttaggt
      301 agtattttca tggattatag aaataatttt gaaaatgata agagtttaat agtctatggt
      361 cattatatga aaaataaaac tatgtttggt cagctagaaa actatactga tgaagtattt
      421 ttcaaagaaa ataatttagt agaaataaat tataaagtac aaacttatac ttatgaaatt
      481 ttttcagtat atactgctga cttaattaac agagattatt taagtataca ctttaataat
      541 aatgatgagt ttaaatattc tttgaattat ataacctaaa aatcagtaca caaatctgat
      601 ataaaggtag atatttcaga taaaattata actttgtata cttgtaaata tgaatttaaa
      661 gatgctctta ctatagttca tgctaaatta atttcaaaaa agagacctat aagtaggttt
      721 gtgtaaatgc agacttatct acagtctttt ttgaacgtaa aattggtaag tatagaataa
      781 tattcatatt aaacttttgt aggcaaagaa atgaaaaatc aaagagaaat aattattaca
      841 gatttagatt accaagctga attaagagag tgtaaaacta tggaggatgt agttggtgaa
      901 gataatatat aatagtttaa cttataaatt atcttggtga tattaatgaa gtttcaaagt
      961 atatattatt tattgatata aataaaatta aatctgtttc taatagatgt acctttgttt
     1021 ggagacaaac tattgaagaa atataactaa aatgttgaag tagctacctg actttatttt
     1081 gaaatgcgaa caagattttg gcattaagat aatttagaaa gaatcactgg tacacaagga
     1141 tgtgaactta gaatgaatag aagtattcag gcataaggag ctttcaccca aataaaacat
     1201 agtatgaact ttaaaagaat tctaatcaaa ggcaatcaaa atattctttc agagtttata
     1261 cctgtagtgt tagcctatag tatttctaag tttcacaaat aagataatca ttaataaatg
     1321 tagtatgtat attcatcctc tcaaaaatat tttttaatct tacactttgt aaattattct
     1381 attttaaaat tgtattttta tacctttatt tcttatgacc gttttcaagc tcaaattttg
     1441 cataaatata aattaatgaa aagcaagtaa aaaaaaactg tcgcacagca atttaaaatt
     1501 actcattcga caatcctttt ttcgtggatt taaatagtgg agaagaatca caagaataat
     1561 acccacgatt aaacctttat acaatacatt ttatatgact ttaccatcac taatagttat
     1621 tatacaatca gccatcttag ctatttcatc attatgagtt atcataacca acgtctgctt
     1681 gtattcattt acacaatact ttagtaaatt catcacctca ttagttgttt tactgtctaa
     1741 atttccagta ggttcatctg caaaaattat tgatggctta ttggcaagtg atcttgctat
     1801 tgcaactctt tgttgttgac cacctgataa ttcattagga aatttattaa tctgactttc
     1861 taatcctaac ttagttatta aatcattaat ataattatta tctatctttc ctttagcaat
     1921 taaaatagga agaactatat tatcataaac attgataaca ggtattagat tatagttttg
     1981 gaatataaac ccaaattctt tacttctaag attagatagc ttttcatcac ttaaagtata
     2041 taaatctaaa ttatccataa atacattacc taaagttggt ttatcaagcc ctgccataca
     2101 gtgaagtaat gtgctttttc cagaaccact ttgtccaatt attgcactaa atttatgggg
     2161 ttctatctct aaagtaattc catcaacagc ctttatttca ttttctcctt ttccatatat
     2221 ttttttaata tctataactt ttaacatctt catacattta cctcccaaat tattcattct
     2281 cttttatacc ttcaataata ttcatacttt caaaatctct attacttaca actactgcta
     2341 ttaaacatac aaatacagat atagcaaaga atagtaaaga ttccttaatt gggaatgtaa
     2401 aagacataaa attctctatt ccatagttta tatacgcatc attattccaa tttgtaaatt
     2461 taactagatt tataaatgat ggaatcatag ctattataaa gctaaaaact gcatatgcta
     2521 atgcttcata tataagcatt tttttcatat ttttaagact aacacctaat gctctaagcg
     2581 ttgaaatttc tttttttcta attagtagat ttgttcttat agtacagaaa atattaattg
     2641 atgctattat taaaactagt gcaattattg ctatttgtga tttaatgtaa cttttatata
     2701 tactttctga catttcatga taacttaatc tactattaaa tagagaccct ggtatacttc
     2761 ttgaaatttt ctgtatctca ttattaacaa tctcatcata tggattttct aaatttatgc
     2821 ctaattgagt gtatttttgt tctcctgtta tgtttttaga gtgaatatta cttgttataa
     2881 tttctagatc tggcataaaa tcgccatctc ccatagcaat ccattcatcc tttaaaatta
     2941 cagccactct taccttcatc tctttataaa caattgtatt attttcttca acaggaattt
     3001 ttacagttat tatgtctcct atatttaatt ctttgaatat aggctttata gtatgatcat
     3061 caactatatc ataaaaataa ttatatactg ctacatttgg atatccatca gtgtcctttt
     3121 taatatcatc taagctacct tcttcaacaa agtcatttaa cttttcatct atataatcat
     3181 catcataaag ctttaaaact aatttatctt ccattatctc ttttttttct actccattat
     3241 aggttgtaaa ttctttgttt atatccttat tattaaaagt aaacattcca tttgttattt
     3301 gaattttatg tatactttta acacccttaa ttttttctat attctctaca tcactatccg
     3361 tgtattttga tatttgcggg tctgcattta ctccaaattg cattgttata ttatatctat
     3421 tttgcatatc ttcaatttta ctgttgacct cttcttgcat acttgagaat gtagtaatga
     3481 atatatatcc tcctaaagca atagacaaca tagatatagc agctctaacc ttatttcttc
     3541 caatattttt aagtcccata aatccataaa atccaaatat tttgcttact agtctgtcta
     3601 ttccaagtct acttctgtga tttttaattt tgtctgtatt tattattgat tcaataggtg
     3661 atatcttgcc gattttaaaa attggtataa tacaagatat aaaaacagaa attattccaa
     3721 ccaatatagc ttttataact atttcattat ttatatataa tttagggtta agaccagctt
     3781 cactgtataa agcttcgtta taattactaa ttcctatata tgaatatgta accccagcta
     3841 ctaacccaag tagtatacct attattgtta taattaatgc ttgatagatt atcatacacc
     3901 ttacgtttct tttctttgca cccatcagtc taaacagtcc catttctttt actgattgat
     3961 ttagtgtaat attgaaaata ttaaatatga aaattataga tactgtagtt attaaaacat
     4021 ttcttttaaa aacattcgga tcactcttat catcttctac ataacgaagt tcccttacaa
     4081 gaggtacatt tggtagaaag cttttttgtc ctaacttata ttttttcata agataatcac
     4141 attcaccttc aatatttctc catccacttt taaaacttaa tatactatta taactaatcg
     4201 catcattagg tataatgttg tttgtttcat cattgccata agttactgct ttgtattgcc
     4261 aaaccacatc atagtaccct tttggttttt ccataactcc tactatttta aattctttat
     4321 ttatagaaaa taattgatta cttccgttag tatctttata gttctttttt attgttaaat
     4381 ttaatgtaga tcctactcct tcacttaaat tcattgcttc tagtgctttt ttctctaata
     4441 ctatttcatt gttgttttta ggtagtctac cttctattat tttgttgtat ctacttttta
     4501 gatactcttc gtttgatgaa gttaatataa atgagtttcc ttttttatct gaaatacgtc
     4561 ctagattttg taccgaatta ccctttgata ctttttcatc agtttctaat tttttagcat
     4621 catcaagtgt caaatcacta aactctacat ggtatccact gtaaagttca tgtattgcta
     4681 ctacattgtt ttcattttgt gaatctttta taacactagg tccaaatatc aacataacac
     4741 ctaacataac tcctattatt aaaagtaatg ttctaagttt atttttcttt aaatatgcta
     4801 gtgacatttt taagtaaatc cccatataat cctcctattt tactataaat tatttatcca
     4861 actcatctgt taagtagatt ggtggatatt ttaaatcttt taattcttca ttattttttg
     4921 aagcttacta ccatcttcct catgataaac ttgtagtatc accttattta catgtagtgc
     4981 ataataatca ccactataaa aatattggta ttcataacct gaataatttt tgtaaaatga
     5041 tttataaagt acccatccta attctctttt gtatactttt cttttgtaat acgctctata
     5101 tcatcacctg aaactccttg atatgtcata tatttatcta tatatttttc agcttcattc
     5161 cattttctaa aatagttgtt gtatataata aatcctatta tggctataat gcttataatt
     5221 aaagttaata aaatagcttt gtattttctc atagtgaatc ttcctacttc aatttaaatt
     5281 ctttaataag ttttaattct aaagacttag ttttatcatc aaatttctta acttgaattt
     5341 ttatatctcc caaattatca acctctatat ttccttcacc tttatcaaat acttcttcaa
     5401 tttttctaaa aaattctttc tcacttattt ctacatgaat caatgatcta tatgttataa
     5461 atggccatta tgaatttatc accttctgac agcttttcat tataagaaaa atctttaaca
     5521 cattgaattg ataatatttc cttcgtaccc ttcttgtcct tagtcattga ataatgtaaa
     5581 acttggctag attgttcttt tgtatactcc aagttttcca aagacaaaac aaaacttcca
     5641 tctgatttat tttcagctac cctaagacca ctattttcta ttgattctga tattttcttt
     5701 gacaagtctt cttgatacta gaaatctgtt caatggtata tattttttca tttgtatctg
     5761 aaaccttatt tgtgcatcct gttattaaac ctagcgttaa gcttatagct ataaccatag
     5821 ttattgtaat tttttttatc ttcatataat ccactttata tattgaaaac tcgttattta
     5881 tcataaaaaa aaagacgcta tctttttcta ttaaaagata acatccctat atgtttagta
     5941 tcaatatatg ttccccaact ggtaggttaa tcgacccaac tatcagtatt ttgatttaat
     6001 ggtatataaa tattcaatat aaatttgtct tttttatctt caaatgataa atctcctcta
     6061 tattttttta tagaagattt gatgctttaa atccctattc catgtacaag tttatctttt
     6121 ttatctgtta ataataaact tttattcttt ctaattgaat ttattttact attctcacat
     6181 ttaattacga aataggactt tgagatagtt ccttttattt gtatatattt atcaatactt
     6241 ttatcatgta tcttatcgca agcttctatt gcattatcta agtatttgca aatatattag
     6301 atacatctat tggttttata aaattcactt tggaaaaatt gatatcacaa atgaatttaa
     6361 tttttctttt ttcacttaca tcactttttt tatttattat tatatccaat ataacattac
     6421 ctgtattgta aattgattta aattctttaa tttaatcttt taaactattt acatacccat
     6481 caattttcct tttttatatt tgagattttc tatacaatat atatgattat ttatatcatg
     6541 ataaagcttc ttaactttag cgtgtgattc ttgaatactt agataatgag aatactgcat
     6601 atctagctta ttttttatta cttcattttg cgattttaac ttattttcct taattgtttt
     6661 tataaacact ataataatta ctaagctact agctagtatt aacctaggta tcacaatata
     6721 cccaactata tatatttcct aatacccacc aaatcgatac atttttctat ttatataaat
     6781 tattaatata gtaaataaat ttgttattaa agcaacagat aagtatatat agtttatttt
     6841 attatcttta tctagtccca atcttttatt aataaattta aatatagcac aagctactat
     6901 ataactatta ttataagata atagtatata tctactttag cattatcata actaaacact
     6961 aatagagctt cctctgatga tattacatta cttgtaacta caaaaaataa atttatagat
     7021 ataacatctt ttattaaagg gtgatatacg tcagataaga aaaatgaaac tatatattta
     7081 acaattccta tcttataaaa ataattatag taagttccca agtaataaat atcaaataat
     7141 agattatatc atatagattt ttcttcatat tataatcatg ggtcttatca acgttaaata
     7201 atataatgat tttagttata agataagcta ataatacagt aaaaaaagat attttcttag
     7261 tcttatctgt atctttatcg taagttaata tactttttag tatcattatt ggtgtaaaca
     7321 atgataatat taataatatt ttatttatat ggtttaacat attctatcac caataaattt
     7381 tagaaacccc tcttttatat ctttatatct atatctacta ataggtactt cttcttgact
     7441 gtctaatatt gcagtatttg actttatatt ttctacatag tttaagttaa ttatataact
     7501 tttatgacat cttacaagtt cctctatatt taaatctttt tctatttttt ctagtataca
     7561 tatagcatca aaagttttat tttttgtatg tattagcatg ttcttttttt gaacttctat
     7621 atattttttt gctagattag attttgtatg tgttagactt atttttattt ttttcaattt
     7681 ttttgataca tgttaatatg tgtttttcta gttcttgaaa atttattggc tttaataagt
     7741 atcaataagc tcttacttca tatctttcct gtacataatt tattagagat gttataaata
     7801 ttattatcta cttttcttat gtttcttgcg atatctatac tatttagttc tgccattttt
     7861 atatctaaga gtagtgtatc ctctcaatta actttgtaat ggttcttctt ttgagctata
     7921 tttttttaat tcgatattct ttgtttttat tttttaatat attatcaact tgatttttta
     7981 ttacgatttg tatttctttt tcatcatcac aagctgctat tgtaatgatg acctctccta
     8041 gtattgtatt tttatttaga ttattcactt taggttaaca ctttttaaat gtatttatca
     8101 ataatattta aattaaaaat gtataaaaat acctatatcc aattggatat aggtattcgt
     8161 ggatttcaat ggtggatacg aggggagtct ataagtggtt atttgattgt tttgttggtt
     8221 ttgtaaaagt tgataataca gcagtttaca tataatacta tataaaattt ttataatttt
     8281 tttgttattt gtttttataa ttggggtata gttggggtat aattatataa agttattaca
     8341 cactataata ttaaactatt ttacaccttt tgatagtgat attacatagt cattatgtat
     8401 ttacctgtaa aaaatatttt attgttatca attggacata tgttattctc atcttctagt
     8461 actttcatag tttctttata catcaatttt acctttataa aaacttcttc tgttaagaaa
     8521 caattttaag ttcaaacaga atcaaacata tcataaacct tgataatgct aaattacaaa
     8581 caatcaatat aagaaatatt cacttataaa attatcattt ttactttaat taataattaa
     8641 accataaaag tatattaata atatcatgct aattttttgt atctcttata agtttttcaa
     8701 gtccattaaa attaattatc tttattctat tattatttaa cttagagttt atggccatat
     8761 tatatgtttt aaatactata attggctgaa tctcttcaat ttcacaacca aatttaattt
     8821 caagattttg tttattctct aatacagatt tatatttttt ctccatttta cttataaatg
     8881 aatatgtttt gtttatatca catttaaatc catatggtgt aaatttataa tatatgtcct
     8941 tacattctat aataaataat ttttttgtaa ctactgcaat taagtcaatc tcattagata
     9001 atgttataat cttttcattg ttaatataaa ctttatgagc atttattata attttatttg
     9061 tatatttctt caatatattg ctacaatcta taactagatt attttttatt tctctttcta
     9121 taatttttga gttaatcttc ttgcattttg gaagaagatt ataaaccaac tttcttatta
     9181 aaatttcata ggaatgtaat aaaataatat aagaaaacat atatatactt atattacaat
     9241 tatttatatt aataaaggct ttttcaagta ttctattaga ataattttcc atagatttta
     9301 atttatcata ttctatagat ttagttatag ttagatattt aatcaaaaat cttatttctt
     9361 caatatcagc acctgaatcg tcacaaaaag ctttgacaag agttttttct tctaccaaat
     9421 gtactaattc tgtatcttta atagttttat ttgtagagtt cagaaatcgt tctatggtct
     9481 caatcctaaa accatatgat ttaaaaaaat tattctttaa tttctctata attttggaat
     9541 catagtctct aatatcaaaa tttaaatctt caatatactc tttgtatatt atttcattat
     9601 cataatatct atctaaatta ttatatatca tataatcatt tatccaaaca ctaatatcat
     9661 cacacaatcc acttagtagc atattttttt ctgctattaa atttgtaatt attaggctca
     9721 tcatataaac atcagtaaat aattttacac caaaattatt ttgattatca ctgtctgatg
     9781 aaaaatgcat gcatttttca attaaatatt gaattgaact tttatcagtt gcacttatag
     9841 aatcaactat aaatcttttt tttaaatttc tttcaatata tcttaatata tctttttcta
     9901 tatgtaatat attactaaag ttgcttgtat tattattcaa tgttataaat actctaccat
     9961 gaaattctgc ttgaaaacat gctattccat atagaatggc cataagctca tttatattac
    10021 tattcctaat tctcttatct atctctgaat ttaagtcatt tattatacaa tcatagacta
    10081 cactaatatc tcttttatct atattaatat tttctaaata tttattatat aataccctct
    10141 ttatctctct attaaagtat atattatata aatttttttc tcctctatta gatattctat
    10201 tccaataaat cttcaaatat atgttaataa tatctcctat tttattattt aaattttgtt
    10261 tcaactcttc tatatacatt gtagtataac cccacttagg ctttagattt ttttcattat
    10321 attacaaatt tcaatctatt atataagttc aaaaagtatc aaatattatt tcttatcttt
    10381 tataagttgc ttcaactcat ctatacttaa aacactatct tttttcctat gaatcattct
    10441 atgacaattt gaacatattg gcactaaatc tgttttagga tttatattac tttcttttcc
    10501 aacagaactt aatggtctaa tatgatgaat ttctatgtat cccttacctc tgtttccata
    10561 tgttttttcg aaatcaaacc cacatacaac acactttgta ccatgatatt ttattgcctc
    10621 tattctattc ttaggattac gctcatattg ttttccataa acatatttaa cttttccttc
    10681 ttttctaatt tcagtttcta attctatatt aatagtatca atgtctaaag gattatcttg
    10741 acttatttcc tctaatacat catcttctat ttcagaagta aaaataaatt ctatatcaaa
    10801 attattacta tcaaatttta caaatcttat tttaggcaaa tttgtttttc cttcaatttc
    10861 atcttctaag aatttctcat aatacttagg aaatatattt cttaataaat ctctaaactt
    10921 agatttccaa attattctac ttcttggatt ctctaattta tccatctcta taactgcact
    10981 ataataatta tcatcatatc taaaattcac atttttcttt tcattcttcc ctaaattatt
    11041 tatctcaaaa aaatgtctta tttctattgg aacccctgtc ctgttgtgtt ttaatgtaga
    11101 tttatcaatt gtttttaaag ctattttctc atctaataac tcccaagaat caactattat
    11161 aggatactta tttatatttt tactttctaa aagtatatta atgatttgtt taaaatatat
    11221 ctcatcttct ttaagcactt caattgcttt atcaattgta tatcccataa aaaccccttt
    11281 atgattttta tttattccta aatgatgcaa tatactcatc gcttgataac ctttattttg
    11341 ttttgatgat aaattcagta tctctccctc tatctttcta ttactcatat ttttttcaaa
    11401 taaataatta taaactactt tatttatttg ctgtgatgta tatttatcaa actctctttt
    11461 tctatcacta ggctctaact taggtattgt catattatcc tcctcaattg attattttag
    11521 attttaataa aattattgta tcatatattt attattaaaa tatgttatgt tatttattta
    11581 aatataaaaa taatacaatg taattgattc cacaaaaaat taaagagggc atccttaata
    11641 ccctctttat aaaatatatt taattcaagg tgttatagta caatttattc ataatctcaa
    11701 tctacaattt aattaatcta ctgaaacata caaaataatt acttcaacag ctcaattata
    11761 aattttactc ctgctttaaa tccgaattta taactaagtt ctctttcaaa ttctattaat
    11821 gaattaaata aatcatttag ttccatcaat acatatcttc tatcttcttc taataaactc
    11881 ttctctaaca attcattagt tgttataatt tctttccaac tttcaatata gtatttgtct
    11941 ttttctaaaa tatctctata catatgttca tttatccaat aatcaaaata tatttctata
    12001 atttcaccat acatgttagt acctccttga ctttcatctg gcacttaata tatacttaac
    12061 ttgtgtaggt tagtgtacat taagtaccta atttataaag gtagttgtta tatttatatg
    12121 gcaactacct ttttctaata aatttttcaa tctaaatact atatatttta aatctttatt
    12181 gcatacaatt aaggattata tacttttctt ctaacactcc ttaaacaata gtttatatat
    12241 cacttaataa attatatttt ttcatacctt cttacattcc ttaaaataaa acaaacttcc
    12301 tatataccaa taaggtctaa agcctgattc cccatctcta tttttagcaa ctataatttc
    12361 acttaaatta gctccaaaac ctttttctct acgtcctaat tcttttatat cctctattcc
    12421 cattatctta caataatcaa gagcctcttt ctctgtaggt ctatgaatat atataactga
    12481 attagaatcc atatatatct gttttgaact tctcattact ctatcacctt ttggtctttc
    12541 atccttcaat tcatcattca attgagctaa ctgtataatt ggaatattaa aatctaaagt
    12601 aatctttttt atttgccttg ataaatcagc aaatttagct tctccaactt ctttaccttc
    12661 gtaatccaaa atctgaagat aatcaattat aacaacatct ggtttaatac tttttatttc
    12721 tctcttaatt cctgatattg tattgactga atcattaata tagagattat tttcctgatt
    12781 taaagtactt aaagcattta tgtatttaat tattttcttc ttcatttaga tttctattct
    12841 tcatttttac aactgatatt ccagttaaag aagctatgtt tctaaacaaa atttgtatat
    12901 cactcatttc ctcacttata aaaagtactt ttttaccttg aaataccaca tttctcatta
    12961 tctgtaagga tagtgctgtt tttcctcttc cacttttggc cgctattgta attaattcac
    13021 cactatatag acctccaata gtttcatcta aaaattttat tcctatatta ataccttctt
    13081 caatttcatc atttatatat tcaaaggctc tttctgatat agctgttata ctagaatcct
    13141 tcttaaccaa tttctgattg acttcattaa tgtatttttc taattgatat ataagtgtat
    13201 tatcatctat ttcccctaat ttgaatttat taaatttatc aattatattt ctatttttat
    13261 atttttcaat aactatatca atataatgag atacattacc tatagttgga actattgttg
    13321 atagttttgt caaataactt atacctccaa cataatctat aagccccttt ttctttaaat
    13381 cttctgtaag agttattatg tctataggct catccctttt atgtatatct ttcactgaat
    13441 tgaatatatg tttgtgttct tgatgataaa acatatcttc acttattaat atttcaatct
    13501 cttctatttt cctcgaatct agtaaaatac tacctaatat agattgttct gcttctgtgt
    13561 tcttaactaa attactcata ttatccataa tataaactcc ctaccacttt aattgtgaat
    13621 catctggact atatgcatct gcccctactt tgacattaat tgatttatct tgataattgc
    13681 cttctaatat cttaagaaaa ttatttggac tcattatcca atcaaaactt gccttccaac
    13741 ctttttcatt gcttccattt aaaaagctag ttttactaac tatatgaata atttctaata
    13801 cagtctcttt atcatattct tttatcctag cattaattac tttttttcta gcttctgtaa
    13861 gtttctttac ttttgatagt tctgtacaag taatattgaa tttttctata atttcactgt
    13921 atattttact tttttcatta tttatattct tgttagttgt tagttgcttg ttaattgcat
    13981 gttgattagt ctgttgattt tcttcattag attgatatag ctcccagttt tcaatagtta
    14041 taagcctatt tttgtttgtt gatttatttg ttagaaatcc atatctttca aatttcttta
    14101 aagcagttct tacattctga atacttacat cttttgaaca catatttgct atactttcca
    14161 aagatgttat taactgtcca gatttaactt catattcttt acctccataa acccatttat
    14221 taggcttatg attaactgac agtaataggt ttatgagtat atctctttgt ttggaattac
    14281 aatctttata tagtgggctt tcttttatct ttctatgaag ctttatccaa cctagattac
    14341 tcaaatacta tcacccactt aagcctataa ttttatgcca tttgcatttt caataaacca
    14401 atcatctagt ttatttttta ttatatacac tctattatct atccatatac aaggaaatcc
    14461 tttattttta gaatgacata actgtctaaa ttttgattcc cctatgggat aaattttaga
    14521 agcttcttta caagtgataa gttgagcttt atctcttcta tatgtctgta tctccttgta
    14581 cccttttgcc ttttcttgtg cttcttgttt gacaagtata ttcaatgtag cttgtagtgt
    14641 tttaagaact tctagattat ttgtatctgc catagatcat tcccccttat caaaaaataa
    14701 ttcttctaca cttgtatcta gttcttgagc caattttaac atcaacatat tacttggatt
    14761 tttggatttg cctctttcta aagaagataa ataatatctt gaaatgccaa ctttctgagc
    14821 taattcatat tgctttatac ctttttcaat tctttttaat ttaagcttca ttgatttcct
    14881 ccttcctcac atacccatat tgtgcctttt tatctttcta caaaacagaa taacacccat
    14941 ttcgtgcttt atcaatatat ttaagtgtat taatacaccc atttcgtgct ataatgtatt
    15001 tgaggtgaaa ttatgataaa taatacaatt ggagaaaaga ttaaacaata tagaaaatca
    15061 ttaaatatgt caagagatga actagctaac aaaattggtt gctcagttca tgctatagct
    15121 aaatatgaac aaaaccaaag aaaacctaat ttagacatta taaaaaaaat atctactgct
    15181 ttatcaattc ccataaatag acttattatt gaagaaaatg atttagatat ttcaacaaat
    15241 aattatacta atttaaaaga atttgattca gttgtaaaaa catttgataa ttactcagca
    15301 aaactcatcg gaaataatat aagcaaattt agaaacataa ataatatctc tattaaagag
    15361 ctctcagaaa aaataaattg ctctgagaat gaaattataa attatgaaaa tggaacaaaa
    15421 atgcctagaa ttgaaatatt aaaaaaaata gcacttgcta cttataccaa tattgaagat
    15481 ttatttggat tcccattaga agagataaaa atagataacc aaacaatcct ttatagaaac
    15541 cctcagactg gatatataat aaatgacttt cttattgatt ttataaataa agatattgac
    15601 atagataata ctccagtttc tcactatata gacaagtctg agtttgattt agtgattcat
    15661 atattagaaa attatggtta tgatataaat acagactata aaacaaagtt tgaaattaca
    15721 gataatgtag atacaataaa accaattaac ctaaacttct ctgatttcaa aaacttctct
    15781 aaaaatctaa attgggtgat aaatggtctt gttgaaaatt ttatacaaga aaattctaat
    15841 ggtcttattg aaaatgaaga tgaggaatat tagtactatg cattttcaca atataaattt
    15901 aattgttaat tttgatatag tcataattag ataagaatta aataaggaag gagctacaat
    15961 catgaataaa tcatatatac caaaatacac atataaattc cctactaatc tacctcatgg
    16021 agataaaaaa tatactttaa catacattag aagaatgata agtgaatttg tatatgatat
    16081 gggtaaacta gaaaataacc cctttacatt cccagaagta caaacattac ttgatggtat
    16141 aacagtaggt ggacataaat taagtgatca aaatcaaata ctaaatataa aatcatcatg
    16201 ggattatgta ataaaattaa gtaacaaaga aaacttatct ttaaataaag atacaatttg
    16261 ctctatacat aaaatagttg caaaagatga agctctaatc gttggagatt tcagaaatgg
    16321 taatataggt atagctggta ctactcaata tgaatgcata gaagccactc tattaaatga
    16381 tttatttgta aatgacataa atatcataaa taaaataact aacccattag aaaaggctat
    16441 aataataaat ttatggttgt cctattgcca attcttctat gatggcaaca aaagaactgc
    16501 tagacttacc tcaaacctaa tacttataag taatgatata ggagttctat caataccagc
    16561 taaacataaa caagaataca acacattaat gctaaacttc tatgaaacac tagaagctga
    16621 tgaagttata aaattcttat tagaaaaatg tattacattt tttgatggat ataactataa
    16681 atcatataag gagctgttta aaaatagcaa ctaaaagagc taatggagaa tgctctatcg
    16741 gaaaatataa agatggttgg cgttcccgta taatgattgg ctataatgaa gatggtaaac
    16801 caataagaaa agaattttat ggtaagactc aaaaggaagt taaagataaa cttgatgctt
    16861 ataaaaaaca atattattta agctctgata tttcagatga taaaataact ttagagcatt
    16921 ggttttacaa ttggttattt gaatatagaa taaaagattt aaaacctaag tcatttgaaa
    16981 gatatgaaag catctatcat aattatatta aagatactga tttaggtaat gttaaattaa
    17041 aggacttaag agtatctcac atacaaaaat attacaatag attgcttgat tccaataaaa
    17101 gtatacctac tataaggcaa ataaacacta aactgaaaac ctgcttatca gaagctgaaa
    17161 aacaaggtct tatacaacgt aattattgta ctatggtaaa tataccagtt gagaaaactg
    17221 tacaagtttt aatgggtcat tatgatatat caataacttt aaatatatac tcaagttatg
    17281 gaagacaaga aagttgaagc tgtagaaaag ttggataaaa tattttcatt gtaaaaatca
    17341 aatacatata aatattgtaa tttcatatag ttaattacaa aatcaaaata aggatacaaa
    17401 ttaattttat attatcttgt atccttattt cgtatctagt tttaattatt tatcttggat
    17461 agcctttatg atacattaat ccattttcta acattaattc ttgagccaag tatatatgac
    17521 ccttacagtg catatctgcc acaccttcac ttataagttt atatgtttca gaagtatata
    17581 aataatccat actttcttcc aagctcttac ctgtttgctt agaaaattct aatatgattt
    17641 ttttatatag tatttgtaat aatgttttat ttgcttccat aatcactata cctcctcttc
    17701 atacctaaac tttaaatatt tatctattac attttgattg gttatacata tttgttcatt
    17761 tggtttatag tattttaatc tttttaaagc ttcatctttt tcaataagat tatcctgata
    17821 cagttctatt gtattgtaaa tcttatcatc agcaatacca cctattataa tgtcatattt
    17881 catatatata tcactcatat ttctacattc tattataaaa tcaagccatt ctaaattata
    17941 actattaaag atttttacct tgcagttttc ttttaattta tcaatatcta aagaataact
    18001 atttaaatat gcttttttac ctcttttttt aaaacgctct gtccagttaa ttgcttgtgt
    18061 ctttatactg gttacataga atccttttcc aaaatctaaa gaatctcttg aaaaggtaat
    18121 actaggagtc tttaccacac aatatgaacc atgatataca atcattatat cacacccttt
    18181 tctttaagta cttgcattaa atcttccact atgtaacctt tactttgaga atgtagtgct
    18241 tcatagcaag gtattatata gttatctaaa atatcagtat catgtttaag aagtttataa
    18301 actccttctg aatctatatt caatttttct gctaaagctt caatgcaaaa aatagaaaat
    18361 tctagttttc tttcatccat tacaaacctc aactcctatc aagcttatat aatatatatt
    18421 tttactaatt aacaacttaa actgtcttac atttataaaa atattatatc ataaagtaga
    18481 tattaaaatt ctgcattagt taatctctaa taaacaaata aagacttttt atacaataaa
    18541 atccctccca atgttctttc aaaaaagctc tttttttgta atcgaaatac aatttaatgg
    18601 atttcatcac ataaataaaa aatactagcc aataaagact agcattttca attattttat
    18661 cattcatttt tcaaaataga taaatactat ttacaaaact cccacaatca cttttattta
    18721 aaatggactt gtttcaccat ttatattgtc ttcaccatat tcagttgatt tttctataac
    18781 ttctttcaat tcgtattttt ctctattata aaaagcaccc tttgttatta cccaatccat
    18841 ttcttcaata caacttacta attctaaatt tttgaaaatt ttatttttat tatatgattc
    18901 aacaatagga ccaaataacc tacattgtcc attattaaca attttattta tgtaagattt
    18961 tatctttgat atataatttc cctctataga tgaaataaaa gatatatacc cttttatttc
    19021 atctaacttt gaataatcct ctttagttat tgcataatgt atcattgctc tgactcttcg
    19081 cttagtatct cttggcacta cgaccttatt cttatctata tgtaagcctg taattttttt
    19141 tcttgaacct ggtctaataa actttgtctt taatttattt atttccatac cttcagattt
    19201 caatatatca agtattacat ttttaatttt aattaataaa acttcatcat tacatgaaaa
    19261 tattaaatca tcagcatatc ttgtataagt aatatctctt ttgcttgcta aattttctaa
    19321 ccttctatct aatctcttac aaattaagtt agatatagaa ggtgatgtta ctccaccctg
    19381 aggcaatact tcattaaaag tgcatatatt acttaatata tttgagatgt aattattata
    19441 tccaatctct ctaaacaaat aaaatacctt ttctctctct atattgttaa aaaaatcttt
    19501 caaatctaat ttaagtatat atgtattata cttatgcaat tctgcattca ttttaatacc
    19561 ataattagtt ccttttctaa aagccatagc acaatttgaa actggtatat tatctaaaat
    19621 ttttactttt atccattttt gaactatttt cattgatata cttggtatac tcaatgttcg
    19681 attgcctgat ttagtttttg gtattattac ttgatgataa aatttatctt gtttttgaga
    19741 taataaataa agaatggtag tactaagccc aatctcagta ctaaatgatt ctagattata
    19801 tattttaggc aaatttaatg attctaatgt cattaaatta ctatatttta aatgcataat
    19861 gacaagtacc tccttaccat aaatcttttg agttaattgt ttcaattttt catacttaat
    19921 gttgaataaa ttgaaacaat tacgaaatat aaatacactt aaattctaac agagacgaat
    19981 catctctaac tataataagt accatataac atgcgcatct atagcaactt ataacagtgt
    20041 tctctaaaga ggtatcttgc catataattc tgaatatagt ataccatacc ttatagaatc
    20101 atacaacttt cctctatttt ttatatttaa attgtatatc attccctcaa catatatatt
    20161 tcctttatca gttaaagata ttttaccact tataatatct ctcttgatat gtctattttt
    20221 atataataat tttaaagaag aactaaatat catattaaat ttttccttct catatttatt
    20281 ttcagtatat atatagttaa ttaatttttt caagtcttta ttagatatat gctttgtaaa
    20341 atatatcact aattgcataa aataatattg tcctattata gtatccacat ccatagtttt
    20401 attttttgac attcttataa actttctaaa tttaaatttt aaaagtgtta tcagtgcatt
    20461 taaatcttca ttataatatg taattctatt acttcctttt tcgttcataa tatactttat
    20521 tggtccagtc gttataaaac ttttttgtgt tttatatttt tcattaatta ctacaaataa
    20581 attctccaat gttcttttat tattagtgaa tgctcctagt tctactaatg atcctgggct
    20641 ttcaggaatt atacaaatta catcactatt atcagctaag aagttctcta aactaagtaa
    20701 gtccatagac ttatttttac taagtatatc cataaataaa tcttcaggat ataaaactcg
    20761 tattttatta ttttcaagtt ctatcctaac catatctctt atacaacttt tattagtact
    20821 tactccccca cataagaata catctatata ttctttatta atatttttat aaatatctgt
    20881 atatatttta ttaactgaat tcaagtaact attttttatt ttcacttaat cctccatatt
    20941 atttagttta ttcttattct actaattata ctatttttaa acaaatatat tttagatacg
    21001 tataggtagc aataatctat atactattaa ttatatcaat tatttagaag atttaaaatc
    21061 aatgtcttat cttaattcta ttatttatat gtataatact atttttagta tatttataat
    21121 ttaatgtata attatacact taaatgcacc ccaatatacc cccaaaaaaa cctctttttc
    21181 tgtggttggg gtacggttgg tggattttac tccaaaataa aaaatactag tcaataaaga
    21241 ctagtatttc atcattcttt tttcaaaatt ggtggagacg aggggagtcg aacccctgtc
    21301 cgcaaatctt ttccttgctg catctacatg cttagccaac ttcactaata tctcacctca
    21361 catagcgcca agtggcaggc tctatgctta gccagtccca attaatctac ttcaagtcga
    21421 gacaccccta aagtagttcc ctgcataatg acgtccagtc ttagtcggca ggaggactaa
    21481 gagggacgag cagcaactag gctgctatcg cgaaattatc gtctgcgttt attttaaagt
    21541 tccccagttt ttacgtgacc cagagtaaca cgacatgcag cctcaagttc caaacccacg
    21601 tcgaaacctt tacgccccct tgagtagttt atagtccagt agacttttcg caaactttat
    21661 caccattttt attaaatttt t
//
LOCUS       DAEPXW010000068        21208 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.069, whole genome shotgun sequence.
ACCESSION   DAEPXW010000068 DAEPXW010000000
VERSION     DAEPXW010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21208
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.069"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            76..1731
                     /gene="ilvD"
                     /locus_tag="KRM55_002512"
     CDS             76..1731
                     /gene="ilvD"
                     /locus_tag="KRM55_002512"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBH1594740.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            2075..2704
                     /locus_tag="KRM55_002513"
     CDS             2075..2704
                     /locus_tag="KRM55_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1594741.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFKQ"
     gene            2730..3542
                     /locus_tag="KRM55_002514"
     CDS             2730..3542
                     /locus_tag="KRM55_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1594742.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSNQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            4090..5181
                     /locus_tag="KRM55_002515"
                     /pseudo
     CDS             4090..5181
                     /locus_tag="KRM55_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
     gene            5180..5591
                     /locus_tag="KRM55_002516"
                     /pseudo
     CDS             5180..5591
                     /locus_tag="KRM55_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            5728..6381
                     /locus_tag="KRM55_002517"
     CDS             5728..6381
                     /locus_tag="KRM55_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1594743.1"
                     /translation="MNNIYSDIYEKLSTLQWIMKRHQMFCQAESGPFADTSRGQGRIL
                     AMLKIQPKIATKELAYLLGIRQQSLNELLNKMEKNGYVERKPSENDKRVMIVHLTEKG
                     KQVQQPKTDYQNIFNCLLPEELLQMSQYLDRIIEAFQLQNGNALEENNMIDWMAQARE
                     RMGDEHFEQLMSMRERAFGHMRPPKDIPGAERFSENYNGYVPDRDGFQPRNFKPDIK"
     gene            6470..7792
                     /locus_tag="KRM55_002518"
     CDS             6470..7792
                     /locus_tag="KRM55_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1594744.1"
                     /translation="MNQKNENYWLLDAPVTKAIWHMAIPMMLGMSINIIYNITDTFFI
                     GRLNDTAALATISLLLPFTTILMAIGNLFGTGGSTLFSRLLGSENTDRTKQCSATTLW
                     LSFLFGLLTAIISIIFSNYIIRLLGADSNTFAYVKQYLIFYGMGAPFIIANFTLEQLI
                     RGDGKSVESMIGMMISIGANIILDPILMFGLQLGIRGAAIATVIGNAFAVIYYIVCIQ
                     RADNQLSALPKYFRLEKQMLKEIFLVGLSAMLLDILLIVSSLMFNYYALKYGDYVLAG
                     FGISQKLVQIVDLIGMGLYMGVIPLIATAYGARNELRVKEIIKKTALYLALVITCLFT
                     ILFTCRNFIVHCFSNDSDVIRIGAYILTVQLCSSFFAAGAGLLTGNFQAKGEGTPAVV
                     MSVMRGIMLIPAIIFGNYLFKMNGVIFSLLVAEAISCITGLVLYKLKK"
     gene            7905..8116
                     /locus_tag="KRM55_002519"
                     /pseudo
     CDS             7905..8116
                     /locus_tag="KRM55_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8214..8573)
                     /locus_tag="KRM55_002520"
     CDS             complement(8214..8573)
                     /locus_tag="KRM55_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594745.1"
                     /translation="MRKKKDTHSFDFRPLGLAIREAREKAGLSRNDLGDKVFYGERHI
                     ADIENIGKHPSFHLFHDLVTMFNISVDEYFYPAKNVEKSTVSRQIDSSLDLLSDDELK
                     IIQGTIDGILNSRENKK"
     gene            8897..9271
                     /locus_tag="KRM55_002521"
     CDS             8897..9271
                     /locus_tag="KRM55_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HBH1594746.1"
                     /translation="MAKTIFEELGGKYERQGDYLIPCLTVPAEEEQPIGTWGQRHLDY
                     LKQYRKVTYTNLLTSGRLNTYLADIDRQAQERFERLIEGMKQAQGITERLKEENALEW
                     TGRMNNIRACAREIVNEEIIFA"
     gene            9515..10438
                     /locus_tag="KRM55_002522"
                     /pseudo
     CDS             9515..10438
                     /locus_tag="KRM55_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782058.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10514..11104
                     /locus_tag="KRM55_002523"
     CDS             10514..11104
                     /locus_tag="KRM55_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH1594747.1"
                     /translation="MFYEAKDFLETADKETLHIISNARKLTREYYFTDYDNTKRKNEI
                     LKELLGAVGKNVAIDVPLHCDYGKNVFLGDDVVINMNCTFVDNKPIRIGSRVLIASNV
                     QFYTSSHPVLPQERFVSDWEETGTTFFRTYARSIEIQDNVWIGGGSIILAGVTIGENS
                     VVGAGSVVTRSIPANCVAVGNPCKVIRCFTEKRGKA"
     gene            11104..11724
                     /locus_tag="KRM55_002524"
     CDS             11104..11724
                     /locus_tag="KRM55_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016304801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1594748.1"
                     /translation="MKYQHIVFDIDGTLINTEHAILHSLQDTLEECIHEKVPVKQLLF
                     VMGITGEDALRQLKINNIPLSLKLWEENIKKYSNTITVYDGIQELLNSLSECDCKIGI
                     VTSKTKAEFKDDFDRFGLKHYFKTIICADDTTGHKPSPEPLLKYIEISGAYNEQILYI
                     GDSKYDSLCAKNAEVDFALAMWGSHTRELEADYFIETPNDLLGAIK"
     gene            11766..11963
                     /locus_tag="KRM55_002525"
     CDS             11766..11963
                     /locus_tag="KRM55_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006863419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBH1594749.1"
                     /translation="MNIEKWILCPVCGGKTRNKIREDTVLINYPLYCPKCRQESLIVA
                     KNMQISIVIEPNAHTYKAVNY"
     gene            11995..12615
                     /locus_tag="KRM55_002526"
     CDS             11995..12615
                     /locus_tag="KRM55_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008751343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1594750.1"
                     /translation="MDNNEKWLQWAVELQSLAQAGIFYGKDVFDKERYERIREIAAEM
                     ISYKSEISMDKVKNLFCNEIGYQTPKIDCRAAVFQNNKILLVQEKNGTWSLPGGWVDV
                     NVSVKENVMKEVKEEAGLDVMADMVIAVQDREKHNLPVYAYKVCKIFILCSVIGGEFK
                     SNIETISSNYFGMNELPILATEKNNEEQIKMCFEAYQSENWKTFFD"
     gene            13197..13664
                     /locus_tag="KRM55_002527"
     CDS             13197..13664
                     /locus_tag="KRM55_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1594751.1"
                     /translation="MELSYTDFCRRRQADQSYMDKLFIPVQGCLLEVVREQYADFYKE
                     KERWRYLKKLDTNHKLLSLEGFTDSEGNVLDFVIDETVDVAETVVHAVMVDSLKAALS
                     LLSGREQALINAIFFEELSEREVGLRLGVTQSVVNKRKSKILAKLRKIIENKI"
     gene            13753..14178
                     /locus_tag="KRM55_002528"
     CDS             13753..14178
                     /locus_tag="KRM55_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1594752.1"
                     /translation="MAYNHGREDRKWRIWKEAEEKILRECGVYEETIEQIRTDDRADF
                     NSNRRFYRWASDFGEYLEGMADREKQAEVKSVSDLLDEIEDETLYLALVTVDRRTLQI
                     VLLKMQGYSTKEIAPLVHLTAGAVYARLNHLRKKLRKIL"
     gene            14261..14734
                     /locus_tag="KRM55_002529"
     CDS             14261..14734
                     /locus_tag="KRM55_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1594753.1"
                     /translation="MAYGAKTYKLREESTESGARYFISFKDGQGEHHELEVSEQLFIE
                     FRQMERRNRNLQQWNQRHREFNEVWDETLYRRALRVPKTLDERMIEKERNEMFLKAVA
                     RLPEIQRRRFLLYYEYDFNFYQIGAMEHCTASAVQKSVSVAREKVKAEMRKYLQS"
     gene            14885..15916
                     /locus_tag="KRM55_002530"
     CDS             14885..15916
                     /locus_tag="KRM55_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015512777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1594754.1"
                     /translation="MQKLQTVNADTLLYEPLEKPSFVVDGLIPTGLTLFCGSQKIGKS
                     WLMLKLCLCVSQGIPLWDMPTREGDVLYLCLEDTFCRIQDRLFRLTDEASGRLYFAVA
                     SDKLSDGLIVQLEDYLKEYPDSRLIVIDTLQKVRTASKDNAYASDYGDISLIKDFADR
                     HSLAVIVVHHIRKQNDSDVFNKVSGTTGLTGSADATFVLEQESRASNAAKLYVTGRDT
                     PYQEFTLRFRDCSWELVERKEQEQLAKEAIPDVLFRLVDFMQDKEEWTGTATELLAAM
                     GETETVPTVITKWLNEYRTTFLSENHICYQYSRKKDGRQIALARQTGDSGDSDDSGIG
                     IPPVTVIDT"
     gene            16440..17405
                     /locus_tag="KRM55_002531"
     CDS             16440..17405
                     /locus_tag="KRM55_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBH1594755.1"
                     /translation="MPYAILRFQKRKAGGVAACERHNERKKEAYKSNPDIDMERSKNN
                     YHLIAPPKYTYKKEINRMVAEAGCRTRKDSVMMVETLITASPEFMNQLPPEEQKEYFQ
                     TALDFISERVGKKNILSAVVHMDERTPHMHLCFVPLTPDNKLSAKSILGNQKSLSEWQ
                     TAYHERMFARWSELERGQSSMETKRKHIPTWLYKLGGRLDKQYEEIVSALSDINAFNA
                     GKKRDKALELLSAWLPDVEKFSKEISKQSAYIDSLKERIGQESDYAGRMRDEKYEQER
                     KVQKANQRIFELQKTNQQMERLLKKIPPEVLEELQKSNRNRARER"
     gene            17414..18268
                     /locus_tag="KRM55_002532"
     CDS             17414..18268
                     /locus_tag="KRM55_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBH1594756.1"
                     /translation="MKKQDFKVLKTADLYPFPDNPFHVVEDEMLSELAESIKEFGIVT
                     PIITRPKEDGNGYEIIAGQRRVRASELAGINTIPAFVLPLDRDRAIITLVDSNLQREN
                     ILPSERAFAYKMKSEAMKRQGFRTDLTSSQVGTKLRTDDKVAQGFGVGRMTVQRFIRL
                     TELIPPILQMVDEGKIALTPAVELSFLKKGEQENLFATMESEEATPSLSQAQRMKSLS
                     QSRRLNMDAIFAIMTEEKGNQKETVKIGMERLKKYFPKGTTPKQMEDTIIKLLERELQ
                     RKRGRDSR"
     gene            18347..18577
                     /locus_tag="KRM55_002533"
     CDS             18347..18577
                     /locus_tag="KRM55_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594757.1"
                     /translation="MKEIQYEIVKEIAVLSTSESGYTKEINLISWNGKEPKYDIRSFS
                     PNREKCGKGITLTADEAAALLKALQEELNSGD"
     gene            18649..18840
                     /locus_tag="KRM55_002534"
     CDS             18649..18840
                     /locus_tag="KRM55_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBH1594758.1"
                     /translation="MGEDKKANKKRKRIVARQPVQMIVSREYVGTQTVAEAFIPIISE
                     DIRRKIAEGDTFDNEDISA"
     gene            18895..20754
                     /locus_tag="KRM55_002535"
                     /pseudo
     CDS             18895..20754
                     /locus_tag="KRM55_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006567773.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT         7027 a         3728 c         4830 g         5623 t
ORIGIN      
        1 ttcgtaatta attaatagaa aaatatatta taataatatt atgaaaattt aaaaaagtaa
       61 gaaagaggta atattatgag aagtgatata aaaaaaggaa tagaaggagc tccaaagaga
      121 gcgttaatgt atggaatggg tcttactaaa gaagaaattg aaagaccatt aataggtata
      181 gtaaatgcac aaaatgaggt gattcctggt catctgcatc ttgatgaaat agcagaagct
      241 gcaaaaaatg gagtaagaat gagtggtggt ttgccattag aatttcctgc tataggggta
      301 tgtgatggta tagctatggg gcatgtcgga atgaattatt ccctggcttc aagagaatta
      361 atagcagatt caatagaagc tatggctatg gcacatggtt ttgatgcttt ggtacttata
      421 cctaattgtg acaagatagt gccaggtatg ttaatggctg ctgcaagact taatatacca
      481 agtattgttg tgagtggagg gcctatgctt ccaggtaaaa aaaatggaaa agtatatgat
      541 tttaactctg caatggaggg tgttggagca tgtaaagatg gaacagtaag tgaagaagaa
      601 ttagaagagt tagccatgaa ctcttgtcct ggatgtggtt catgttctgg tcttttcaca
      661 gcaaatagca tgaattgttt aacagaagct ttaggcatgg gtataccata taatggtact
      721 gctgcgtcac attctggaga aagaaaaagg atagcaaaat atgcaggtat gtatgttatg
      781 gagttactta agaacgacat aaaacctaga gatattttaa caatagatgc ttttaaaaat
      841 gctatagctg tggatatggc aatggctggt tctacaaata cagtacttca cttacctgca
      901 atagcttatg aatcaggaat agagcttaac ttagattttt ttgatgaaat aagtgaaaaa
      961 actccttgtt taacaaaatt aagtccaagt ggaaaacatc atattgaaga tttacatatg
     1021 gcaggaggaa taccagctat aatgaacgaa ctttcaaaga taaatggaat aaatttagat
     1081 tgcaaaaccg taacaggcaa gactataggg gaaaatataa gaaattgtga aatagaaaat
     1141 gaagaagtaa tacatacatt aaagaatcca tatagtaacc aaggtgggct tgcaatattg
     1201 aaaggaaatc ttgctctaaa tggagctgtt gtaaaaaagt cagcagttgc agaagaaatg
     1261 ttagttcatg aaggaccagc aagagttttt aattcagaag aagaagctgt aaatgctatt
     1321 tttggtaaaa aaataaacaa aggtgatgtt atagttataa gatatgaagg tccaaagggt
     1381 ggtccaggaa tgaaagaaat gctatctcct acatcagcag ttgcaggaat gggacttgat
     1441 aagcatgtag cacttcttac tgatggtcgt ttttcagggg caactagagg ggcatccata
     1501 ggccatattt ctccagaagc tatggaaggt ggtttaatcg gactagttga agaaggagat
     1561 ataatttcta taaacatacc agacaaaaaa ttagagttaa aagtagatga agttgaaata
     1621 gaaaatagaa aattaaaatt taaaccttta gaaccgaaaa taaagcatgg atacttaagt
     1681 agatatgcta aactggtaac atcagcaaat acaggagcag ttttaaaata gtagactata
     1741 tttatgtaaa ttagaaaaag ttaagaaaat attaattgga tatcttaggt gttatagcac
     1801 taatgaggta tcctttttat tttgtatgaa aaacatagca aaatcttgat tatctttgaa
     1861 aacaatacat ctctattata aggaatacaa gtacagcata gagatgtatc ttttagacct
     1921 tgttgaggta atacaacttt ttaaaagttt gatgtggaat gcttttcgtt ccatctgaac
     1981 tatgaagaaa ttgaaagtca gttaattctt gacataataa atattaaaat gtataataaa
     2041 aaacaaacag acagtctgtt tttaggaggg aaatatgaat agagaagaaa aaagtaaaaa
     2101 tagtaaagaa aaaattatcc aatcagcatt ttcactattt tcgtctaaag gatatgattc
     2161 aacatctaca caagatatta tcaatttatc tggtctatct agaggtgcaa tgtatcatca
     2221 ctttaaaact aaagaagata tactgagaag tgtcacaaaa gaactttact cacaaatgaa
     2281 taatttttta gagcatcttg ttgctgatga cacccttaca gcaaatgaaa aaataataga
     2341 attggttgtt catagtgcga atgattacac acgtagaaaa atggtacatt gtagctggtt
     2401 agaaaaaatc ccattcgctt taatagagga agttcgtaat ctcaacaatg tagttgcacc
     2461 caatattgct aagataatta aacaaggtgt tgaaaataaa gaattttctt gtgaatatcc
     2521 agaggaatta gctgaaatgc tcgtttttag tattgatatt ttacttgacc ctgtattatt
     2581 taaacgtgaa tacagtgaag tatgtaatag gttggatttt ttattattca tgttaaaaaa
     2641 aatggatatt cctctaattg atgagtacgg tattcaaaaa tttaaagatt tatttaaaca
     2701 atgataatag gaaaagtgag gaatagacta tgttttataa tgcaaaaagc tgtcaaatga
     2761 tgataggaag taatacagtg aattatattg aatttggtag tggtaagaag acactaatta
     2821 ttttaccagg attaggagat ggtttatttc ctttacatgg aaaaatacaa gcgattgctt
     2881 ttgcttttag atataagcaa tttgcaaaag attataaggt ttatgtattt agtagaaaaa
     2941 atcaaattac agaaaaatat tccacaaggg atatggctaa agaccaagca gatataatga
     3001 aaaaacttgg aattatgaaa gcagaagtaa tgggtgtttc tcaaggtgga atgatagctc
     3061 aatatctggc aattgattat cctgagttag ttgagaaact tgtgttggca gttacttctt
     3121 caaatcaaaa tgatactatc caaaatgtta tttgtagttg gattgatatg gcgaagaagc
     3181 agaattacaa tgatttaatg attgacacag caaagaaatc ctattctgaa agatatttaa
     3241 aaaaatacca attatttatt ccttttttag gaaaagtagg taaaccaaag gattttaaac
     3301 gatttattat tcaagcgacc tcttgcatag aacataatgc cttttccgaa ttaaataaaa
     3361 taacatgtcc aaccttaatt ataggaggtg ctaatgataa aattgttgga aataatgctt
     3421 cttttcattt agcagaaaaa attaaaaaaa gcgaaatatt tatctatgag ggattgggac
     3481 acgctacata tgaagaagca caggatttta atgaaagagt tttagagttt ttaaataagt
     3541 aaacaccttt gttaaaaata tacatatgaa gattggaaat ttaatgttaa aaatagaaac
     3601 atgaaaatat gcttaactgg tatttttact attcataacc aatttttgat acattatcta
     3661 ctataaatac aaatatagct tcaatgtgat tatatattgg tgtattggta aagcacttat
     3721 acaaacagag gaattttgta aattcatatt atacccacat ttgttaactt atgaaaatat
     3781 aatcaaaatt tttatgagat ttttatataa aaaacgccct aaaaatctta ttatccccat
     3841 aaacactgta tctaaaagca tattcaatag gaaataaatc gtgatattac tacgaattta
     3901 ctactaatga atgagccttg atacgtctta tttcccagat atgcaaagat atggcatggc
     3961 acatcagtaa aaattgaata cttatataga ctatggaacg tacacttttg gcgtttcttt
     4021 tctatttcca gatgttcttt tcagagcgtc tttttttcat acccaaaatc gaaaggagaa
     4081 agagaaaata tgaataagct agtaaagcga ttgctgacag ggacgctcgc cattgcaacc
     4141 attcttaccg cattgcctgt gacggtggtt catgcttctg gcaatcaata ctggacagaa
     4201 tcagcagaac gtgtcggcta cattgaacat gttatgaatg atggttctat caaatccaca
     4261 ttaaatgagg gacacatgaa agttgagggc gaaactgcct attgcgtgga catcaataca
     4321 aatttcaaaa atggatataa aacaaggtat gacgcaagct cccatatgag tagcgatcag
     4381 attgcggaca ttgctctttc cttagagtac atcaagcaat atactgcttc tcatacaaac
     4441 ttgaattaca agcagggtta cttattggaa cagtgtgttg tctggcagag attgagtgaa
     4501 cagctcggct ggcaatgtga taacgtcaga gcttcctata atgaaatctc acaggcggta
     4561 cagaataaag tttacgctgg tgcgaaagta tttgtgaaag caaataaggg atgctatgaa
     4621 tgtggcggtt acatctacac tggcgaagga caggacattg gacagttctg ggcgaagttg
     4681 aatgtgggaa atgaaaaggt caaaaagact tcttccaatt ccaccctcta cagatggcaa
     4741 tgtcaattat tcctttgagg gggcaacatt tggcgaatcc catattgtag tcacagataa
     4801 aaacggtcag ttctctactg cttcaagttg ggctttccgt aaggtaaata caaatgctgg
     4861 aaaatccagt gaggatggtg tatggtttgg tacttctgaa ccagacgaca gtaaaggtgc
     4921 attacctatg tgattgagga attaaagtgt gattccaacg ccggatttaa gctgattcca
     4981 gcttttgagg tggtcgtatc cagaaaaaaa gtgaccgtag atttagggac acttactgat
     5041 gaatatgaaa aagaaatcac aatccatacc acagctaccg acaagaaaac aggcgaaaaa
     5101 atgattgttg ccggaaaaga catcaagatc gtggacaaag tcacacttga tggcttggaa
     5161 actggcagtc acagaaaatt acaccgtgac cgttcatgtg tatacagatg gtgaaatggg
     5221 tcattaccca gaatcctacc cttgctccgg tggtacagaa atcaaagtat gaaccgaaag
     5281 cacagggagc agatgtcagc gtcagctcct atacgttcaa agacgctact actttcttgg
     5341 aaacattctt taaactctat ccgacagcta cagaaaaaga acttgcctat tatgtcaaag
     5401 acggtgtgct tgctcctgtt tctggcgact atgtattttc ggaactggta aatcctgtct
     5461 ttaccaaaga tggcgataat ctcaaggtca gtgtgtccgt gaaatatctg gataacaagt
     5521 cgaaaatgac acaaatctca cagtatgagc ttgtgcttca caaggacgat aattggaaaa
     5581 ttgtaggata aatattacag cagaccagct atgacaattt caaatacata tactaagttt
     5641 taaaaatata catgtaccct attgactttt tgggaaggta cctgtatatt atttgttaaa
     5701 ggtacctgtt gaaaaggagg tcatactatg aataatattt attctgatat ctatgagaaa
     5761 ctatcaacct tgcaatggat tatgaaacgc catcagatgt tttgtcaggc agagtctggt
     5821 ccatttgctg atacatcacg aggacaagga agaattcttg ctatgttaaa aattcagcca
     5881 aaaattgcaa caaaagagtt ggcatattta ttgggaatac gccaacaatc cctaaatgag
     5941 ttgcttaata aaatggagaa aaatggctat gtagaacgaa aaccatctga aaatgataaa
     6001 cgcgttatga ttgttcattt gacagaaaag ggaaagcaag ttcagcaacc gaaaacagac
     6061 tatcaaaata tctttaattg tctacttcca gaagaattgc tacaaatgtc gcaatattta
     6121 gatcgtatta ttgaagcttt tcaattgcaa aatggaaatg ctttagaaga aaacaatatg
     6181 attgactgga tggctcaggc aagagaacgt atgggcgatg agcattttga acagttaatg
     6241 tctatgcgtg aaagagcttt tggacatatg agaccaccca aagatatacc gggagctgaa
     6301 cgcttttctg aaaactataa cggatatgtt ccagatagag acggatttca gccaagaaac
     6361 tttaaaccag atatcaaata acaaaaggca ctgtaaaatt acagcaataa gccctatgga
     6421 gattttttga actccatagg gcttattttt tgaaaaggag acgaacaaaa tgaaccagaa
     6481 aaatgaaaat tactggcttt tagacgcacc tgtcacaaaa gctatatggc atatggcgat
     6541 tccaatgatg cttggaatgt caataaacat tatttacaat attacagata cattcttcat
     6601 aggcagatta aatgacacag cggctcttgc cacaatctca ctgctgttac ctttcacgac
     6661 cattttaatg gcaattggga atttgtttgg aacaggtgga agcactttgt tttcacgact
     6721 gttaggaagt gaaaatacgg acaggacaaa acaatgttca gctacaacat tatggctatc
     6781 tttcctgttt ggactattga ctgcaataat atccatcatt ttcagtaact atattatccg
     6841 acttctcggt gctgatagta atacttttgc ctatgtcaaa cagtatctta ttttttatgg
     6901 aatgggtgct ccgtttatta ttgccaattt tacgctagaa cagttaatta gaggtgacgg
     6961 taaatctgta gaatctatga ttggaatgat gataagcatt ggtgctaata tcattcttga
     7021 cccaattctg atgtttggat tacagcttgg tattcgtggg gcagccattg ctacagtaat
     7081 cggaaatgct ttcgctgtta tctattatat tgtctgtata caacgagcag acaatcagtt
     7141 atctgctctt ccaaaatatt tcaggcttga aaaacaaatg ctaaaagaaa tttttttagt
     7201 tggattatct gcaatgttgt tagatattct tttgattgtt tcaagcctta tgtttaatta
     7261 ctatgcacta aaatatggag attatgtgct tgccggattt gggatttctc aaaaacttgt
     7321 gcagattgtc gacctaatcg gcatgggact ttacatggga gtaattccac ttattgctac
     7381 tgcctatggt gcaagaaatg aacttcgtgt gaaagaaatc attaaaaaga ctgctctcta
     7441 tttagcacta gtaattacat gtttgtttac tattctattt acatgcagaa actttattgt
     7501 tcattgtttt tcaaatgatt cagatgtaat tcgtataggt gcgtacatct taaccgttca
     7561 actctgttct tctttctttg cggcaggagc gggtcttcta acgggaaatt ttcaggcaaa
     7621 aggagaagga actccggctg ttgttatgtc cgttatgaga ggtattatgc tcataccagc
     7681 aattatcttc ggcaattatc tctttaaaat gaatggagtt attttttctc tgcttgtagc
     7741 cgaagctatt tcatgcatta cagggcttgt attatataaa ttgaaaaagt aatgctgaac
     7801 tccatcagac ttgttaacaa agttagtgat ggttataaaa atcatcaaca ataaattaag
     7861 agatttctat agaatgagta tagattggta ggagctggaa aaatatgatt gggcttaaaa
     7921 aaagaaatat aaaaaaatgt tgaaaactgg tgatagagct ggagatgtat cattagctga
     7981 tattcgggct aatatagaag ccactattga tgaagacatg aacagtccag ccccagaggt
     8041 acaggcaaat ttcaaaaagt attttggcaa taaacgtcct acaccagaag aatatattta
     8101 caagattaca aaaaaacaaa agtttgattt acgactattt gttgcctgcg gagtatatca
     8161 acaaataagc gttaaagaat ctgcacagaa aaacagagaa aataagaagc gaatcacttc
     8221 ttattctctc tgctgttcaa gataccatca atcgtacctt gaatgatttt taattcgtca
     8281 tcactcaata aatcaagtga cgaatctatc tgacggctaa ctgtgctttt ttccacattc
     8341 ttcgctggat agaaatactc gtcaacagat atattgaaca tggtaactaa atcatggaat
     8401 aaatgaaagc tagggtgttt cccgatattt tcaatatctg cgatatgacg ttctccgtaa
     8461 aagactttat cgcctaaatc atttctggaa agccctgctt tctctctggc ttctctgatt
     8521 gcaagtccta aaggacgaaa atcaaagctg tgcgtatctt tcttttttct catttttaat
     8581 cacctagcat gagtttatac tattttcaca ggtttgctct gctcaaggag caatttgtga
     8641 ttctaagtaa aacaggcagc cggcaccgac aaccgaattt attccttttt tttagtttat
     8701 catcagccct tgagcatgaa ttaaaaactc atatatcaga tgttttaaat acagtctatt
     8761 tgttattagt gcagataggc tgttttcata ttttcaaaaa gtttttcaat tctgcaacaa
     8821 atcacaccct gctgtacaga tgtagaacgg attttgcgga cattcaaaat aaaaaagaat
     8881 gtggaggtaa cagacaatgg caaagacgat ttttgaggaa ctgggcggca aatatgagcg
     8941 gcaaggagat tatttaatac cgtgcttgac tgtacccgcc gaagaagaac agccgatagg
     9001 cacatgggga cagcggcatc tggactatct gaagcagtac cgaaaggtta catacaccaa
     9061 tcttctcaca agcggcaggc tcaacactta ccttgccgac atcgacaggc aggcgcagga
     9121 acgctttgaa cggctcatag agggcatgaa acaggcgcag ggcataacag aacgcctaaa
     9181 ggaagaaaat gccctagaat ggacaggaag aatgaataac ataagggcgt gtgcgaggga
     9241 gattgtgaac gaagaaatca tttttgcata agtagagaag ggcggcagag tgtaaaagct
     9301 ctgctgtcac tgttttaaat taacaatctg ttttcgttgc atatatgaca ttttcaaata
     9361 aatcgacaga gagctgccct atgctattga tacaattcat tggaacccct atactatatg
     9421 gtgtatagct atttcccaca aaagtgagaa atctgctgat gtgaaaaaaa tctgaaaaca
     9481 aactgaatga tacaatgtga aagaggaatt ttgtatgaag aatgtatata aacttgaatt
     9541 tcattcggga agcaaagaag aattattgcc tgattttgaa tctgaatttc cgtatattgc
     9601 atctaatgca gaacttgaca aatatattgg gcgttctgcg ccgtggcatt ggcatagggc
     9661 aatagagctt ttttatatgg agagtggcac attagaatat tacacgccga aaaagaaatt
     9721 gtctttttcg gcaggttctg gaggttttat caattcaaat gtccttcaca tgactaaggc
     9781 tgtttctagg acagaaaaaa atatacagcg gctgcatatt tttgacacag ctcttatttc
     9841 tggaaactat gggagtaaaa ttgagaaaaa gtatgttatg ccaattactg caaatcccca
     9901 aatttaaata tatgctttcc gccccgataa ttttatacac gcagatatat tggatttgat
     9961 aaaacagact tttaccttat gcgagaatga cattggatat gagataaaga taagggaatc
    10021 cctgtcccga atatggctaa agctttttga gctgttttct gcttcatttg atgggaaagg
    10081 aaaatatgat aaaaatgacg aaagacttaa gaagatgtta atttacatac acgaacattt
    10141 tgcggataaa attgcggttt cagaacttgc cacagttgca tgtttaagtg aaagggaatg
    10201 tttcaggctg tttcaaagct atttgcatac aacgcccaca aagtacatcc aaagttaccg
    10261 tttacaagaa gcttgtgaaa tgctcataaa tgggcaggac acaattacag acattggaca
    10321 tgcctgcggg ttagggaaca gcagctattt tagcaagatt ttccgtgaat accaaaactg
    10381 cactcccata gaatatcgga agaaatggca ggatagtcat atcttatgtc cgaaataaaa
    10441 tagataaata aataattctg cgttataatg atatatagca catattttgt tatatcattt
    10501 taaggagaac gctatgtttt acgaagccaa agattttttg gaaaccgcag ataaggaaac
    10561 tttgcatatt atttccaatg caaggaaact tacaagggaa tactatttta cggattatga
    10621 taatacaaaa agaaaaaatg agattttgaa agaattgttg ggagctgttg ggaaaaatgt
    10681 tgccattgat gtcccgcttc attgtgacta tggaaaaaat gtatttcttg gtgatgatgt
    10741 cgttataaat atgaattgta catttgtgga caataagccc atacggattg gcagtcgggt
    10801 attgatagca tctaatgttc agttttatac atcttcccat cctgttttgc cacaggagcg
    10861 tttcgtttcg gactgggaag aaactgggac aacatttttc agaacttatg cccgttccat
    10921 tgaaatacaa gacaatgtat ggattggagg gggaagcatt attttagctg gcgtaacaat
    10981 cggtgaaaac agtgtggttg gagcaggaag tgttgttacc cgttcaattc ccgcaaattg
    11041 tgttgctgtt gggaatccgt gtaaagttat tcgctgtttt acagagaaaa gaggaaaagc
    11101 ataatgaaat atcaacatat tgtttttgac attgatggga ctcttatcaa cacagagcat
    11161 gcaattttgc actctttaca agacacatta gaagaatgta tacatgaaaa agtacctgtc
    11221 aagcaattgt tatttgtaat gggaattacg ggagaagatg cattaaggca gttaaaaatc
    11281 aataatattc cgttgtcttt gaaactatgg gaagaaaaca taaaaaaata cagtaataca
    11341 ataactgttt atgatggaat ccaagaatta ttaaacagtc tatcagaatg cgattgtaaa
    11401 attgggattg tcacctcaaa aacaaaagca gagtttaaag atgattttga taggtttggg
    11461 ctgaaacatt attttaagac gattatttgc gctgatgata caacagggca taaaccatcc
    11521 cctgaacctt tgttaaagta tatagaaatt tctggggcat acaacgagca aatattatac
    11581 ataggtgata gcaaatatga cagcttatgt gctaaaaatg cagaagttga ttttgcattg
    11641 gcaatgtggg gaagccatac cagagagttg gaagccgatt acttcattga aactccaaac
    11701 gatttactag gcgctataaa ataagcagga atgataagaa aataattggg caaagaggtg
    11761 gttttttgaa tatagaaaag tggattttat gccccgtttg cggtggcaag acacgtaata
    11821 aaattagaga ggatactgtt ttaataaatt atcctcttta ttgtcccaaa tgcagacagg
    11881 aaagtttgat tgtagcaaaa aatatgcaaa tcagtattgt catagagcct aatgctcata
    11941 catacaaagc ggttaattat tagaatgata ttaacttgca gacaaggagg acacatggat
    12001 aataatgaaa aatggctgca atgggcagta gaattacaaa gtctggcaca ggcaggaatt
    12061 ttctatggaa aggacgtttt tgataaagaa cgctatgaaa gaattagaga aattgcagca
    12121 gaaatgattt cttataaatc agaaatttca atggataagg tcaaaaatct attttgtaac
    12181 gaaattgggt atcaaacacc taaaattgac tgtcgtgctg ctgtttttca aaataacaaa
    12241 attttgcttg tgcaagagaa aaatggaaca tggtcattgc ctggaggttg ggttgacgtt
    12301 aatgtttcag tgaaagaaaa tgtgatgaaa gaagtaaaag aagaagctgg tttagatgta
    12361 atggctgata tggttattgc cgtacaggac agggaaaagc ataatttacc agtttatgcc
    12421 tataaggtgt gcaaaatatt tatattatgt tcagtcatag ggggcgagtt taaatccaat
    12481 atagaaacca tatcgagtaa ctactttggg atgaacgagt tgcctatcct tgcaacagaa
    12541 aaaaataatg aggaacagat aaagatgtgc tttgaagcat atcagtctga aaactggaaa
    12601 acattttttg attagtattt tttagaaaga gccagacact ttagatgcag agccaatgaa
    12661 cttgtgaaat agaatcacag tttattggct ctatttcatt tcataagatt ttaaggcaaa
    12721 cgcccaccaa ataaaaaaaa cgaggttcgg tgggcggtat tgctatgccc gaaaagactt
    12781 aacagacact ctccagacct gttttagagt ttggagggat ttttttatgt tcttttttcg
    12841 ggtagttatt catctgctca tgcaacgcag agtttaccca tacatagcat atcggggaat
    12901 ggcaggaagc cagtcaaaaa agttcctgct tatgcaacgc tacttcacgc cttgaaacca
    12961 gaagtagaat ctccacctaa cagaatatgt atctcctata accgtagaag tcacagaact
    13021 tttgcggttt ttcttttgtc gttttttatc ggaatgtgcc gcagggctag ttcttgtgtt
    13081 ggctgtcgtt cgccgccttt tccatctgga ttttaacaat tcaaaaattc agatgggagg
    13141 tacttacggt gaagtatgca ccaagaaaag tatatatcaa gaaaaatggc ggttatatgg
    13201 agttatccta tacggacttc tgccgccgca ggcaagccga ccagagttac atggacaagc
    13261 tgtttatccc cgtgcagggc tgtctgcttg aggtagtgcg ggaacagtac gcagattttt
    13321 acaaggagaa agagcggtgg cgttatctga aaaagttgga cacaaaccac aagctgctct
    13381 cattagaggg ctttacggac agtgagggaa atgtgcttga cttcgttatt gatgaaacgg
    13441 tggacgttgc ggaaaccgtt gtccatgcgg tgatggtgga cagtctgaaa gccgccctgt
    13501 ctttattgtc gggcagagag caggcattga taaacgccat cttctttgaa gaactttccg
    13561 agcgggaagt cgggttgcgg ttaggcgtga cacagagcgt tgtgaacaag cgcaaatcca
    13621 aaatccttgc gaagctgagg aagataatcg aaaacaaaat ttaaggcgtt cagccccctt
    13681 gttttttcct ttgggaaaat gagggggctt ttccctgccc cctcaatcaa ttctgattgg
    13741 aggaaaaaaa gaatggcata caaccacgga cgggaggaca ggaaatggcg catctggaaa
    13801 gaagcggaag aaaagatttt gcgagagtgc ggcgtttatg aagaaaccat tgagcaaatc
    13861 cgcacagacg acagggcaga ttttaattcc aacaggcggt tttaccgatg ggcgagcgac
    13921 ttcggcgaat accttgaggg catggcagac agggagaagc aggcggaggt aaagtctgtt
    13981 tctgatttac tggacgagat tgaggacgaa accctgtacc ttgctttagt tacggtagac
    14041 aggcgcacgt tacaaatcgt cctgctgaaa atgcagggct attccactaa ggagattgcc
    14101 ccgcttgtgc atttaacggc aggggctgtc tatgcgaggt taaaccatct gcggaagaag
    14161 ctgcggaaaa ttttataagc gtctcatata tcctgctttc ctatgggcta tcgggtgggg
    14221 agggaaaact ctctcctact ttttagcagg aggaaaggga atggcatacg gggcaaagac
    14281 atacaagctt cgggaggaat ccacggaaag cggcgcaagg tattttatca gctttaagga
    14341 cgggcagggg gaacatcacg aactggaagt gtctgaacaa ttattcattg aatttcggca
    14401 gatggaaagg aggaacagga accttcagca atggaaccag cggcacaggg agtttaacga
    14461 ggtgtgggac gaaacccttt acagacgtgc gttaagagtg cctaaaacgc ttgatgaaag
    14521 aatgattgaa aaagaacgaa atgaaatgtt ccttaaagcg gttgcccggc tgccagagat
    14581 acaaaggcgg cgtttcctgc tctattacga gtatgatttc aatttttacc aaatcggcgc
    14641 aatggagcat tgcacagctt ccgctgtcca gaaatctgtt tcggttgcaa gggagaaagt
    14701 taaggcggaa atgaggaagt atctccaatc ttaacgatta ctgcccgaaa aaaaaattca
    14761 tttttatcgg cgtggggatg gcggcattac atactctcac ttctttgtgt gggagtaaat
    14821 ctatttaagg aggtcacgcc tatgtgcaac aaaaccaaag acactgcccg aaaggaggaa
    14881 agccatgcag aagcttcaga cagtcaatgc cgacacgctc ctctatgagc cgcttgagaa
    14941 gccgtccttt gtggtggacg gtctgatacc cacgggctta accctgttct gcggctcaca
    15001 gaaaatcggc aagagctggc ttatgctaaa gctctgccta tgcgtgtcgc agggaatccc
    15061 cttgtgggat atgccgacac gggagggcga cgtgctttac ctctgccttg aggacacgtt
    15121 ctgccgcata caggacagat tgttccgctt gacggacgaa gcaagcgggc ggctctactt
    15181 tgcggtggcg agcgacaagc tgtcagacgg tcttatcgtg cagttggagg attatctgaa
    15241 agaatacccc gacagcaggc tcattgtgat tgacaccttg cagaaagtcc gcaccgcatc
    15301 caaagacaat gcctatgcaa gcgactacgg ggacatctcc cttatcaaag actttgccga
    15361 caggcactca ttagcggtca ttgtcgtaca ccacatccga aagcagaacg acagcgacgt
    15421 gttcaacaaa gtgtctggca cgacgggatt gacggggagt gcggacgcaa cctttgttct
    15481 ggaacaggaa agccgtgcgt ccaatgccgc aaagctgtat gtgacgggca gggacacgcc
    15541 ctatcaggag ttcacgctcc gcttccgtga ttgcagttgg gaactggtgg aacggaaaga
    15601 gcaggaacag cttgccaaag aagcgatacc agatgttctt tttcggctgg tggattttat
    15661 gcaggacaag gaggaatgga cgggaacagc aacggagctg ttagccgcta tgggggaaac
    15721 ggaaaccgtc cccacggtga ttacgaaatg gctcaatgaa taccgcacca cgtttttaag
    15781 cgaaaatcat atctgctacc agtacagccg caaaaaagac ggcaggcaga tagccctcgc
    15841 aaggcagacg ggtgacagcg gtgacagtga tgacagcggt attgggatac cccctgttac
    15901 tgtcattgac acctaaagcc atgtaaagct ggcggctctg ccctgcgggt gacagcggtg
    15961 acggtgatga cggcaatatt gggatacccc cgccgctgtc atccctacgg gagaacaccc
    16021 cgtaaacgca agatgcaggc gtgggcatta ctcgcccttt tcggctcgta aagccacccc
    16081 tgcggtcaga aaaatctacc gattttcccg actgcgttta cagggtgtaa cacactacac
    16141 tttgccctgc aaagagccgt gtgccagacg ttccctctgg actcccttaa agcagggctt
    16201 acgccctgcc catcctgcgc cttgcggctt cggatggaag aatgtgcggt gacagtcggc
    16261 ggctaagagg gggtatccca aaaacaccgt catcatcgtt atgaccgtca cgcaccagag
    16321 aaagacggca ggacggtgac agtgacagcc aagagggggg tatcccaaaa tcactgtcat
    16381 caccgtcacc actgtcacac aaaggacagt tacccgccga agaaaggagg aatcctgcca
    16441 tgccctatgc aatcctgcgt ttccagaaac gcaaggcagg cggcgttgcg gcttgcgaac
    16501 gccacaacga gcggaagaaa gaagcctata aaagcaatcc agatattgat atggaacgct
    16561 ctaaaaacaa ttaccatctc atagcaccgc caaagtacac ctataaaaaa gagataaacc
    16621 gaatggtagc tgaagcagga tgcaggacga ggaaagacag cgtgatgatg gtggaaacgc
    16681 tcatcaccgc atcgccagaa tttatgaacc agttaccgcc cgaagaacaa aaagagtatt
    16741 tccagacggc tcttgacttt atttcggagc gtgtgggaaa gaaaaacatc ctctccgcag
    16801 tcgtccacat ggacgagagg acgccccata tgcacctatg ctttgtgccg cttacgccag
    16861 acaacaagct gtcagcgaaa tccattttag gcaaccaaaa gagcctttcc gagtggcaga
    16921 ccgcctacca tgagcggatg ttcgcaaggt ggagcgaatt ggaaaggggg caatcctcaa
    16981 tggaaacgaa gcggaaacac atccccacat ggctctataa gttgggcggc aggctggata
    17041 aacagtatga agaaatcgtg tctgccctct ccgacatcaa cgcctttaac gcaggaaaga
    17101 aaagggataa ggcgttagaa ctgctctccg catggcttcc agacgtggag aaattctcaa
    17161 aggaaatcag taaacagagt gcttatattg acagtttaaa agagagaatc gggcaggaat
    17221 ccgactatgc ggggcgtatg cgtgatgaga agtacgagca ggaacgaaag gtacagaaag
    17281 ccaaccagag gatatttgag ttgcagaaaa ccaatcagca gatggaacgg ttattgaaaa
    17341 agataccgcc agaagtgtta gaggaattgc agaaaagcaa tcggaataga gcaagagaaa
    17401 ggtaggtagc agattgaaga aacaggattt taaggtatta aagaccgcag atttataccc
    17461 gtttcccgac aacccgtttc atgtggtgga ggatgaaatg ctgtcagagt tggcggaaag
    17521 cattaaggag tttggcattg taacgccgat aatcacacgc ccgaaagagg acgggaatgg
    17581 atatgaaatc attgcgggac agcggcgtgt ccgtgcttcc gagcttgcag ggataaacac
    17641 aatccccgct tttgttctgc ccttagaccg tgaccgagcc atcatcacac ttgtagacag
    17701 caatctccaa agagaaaata tcctgccatc ggagcgggca tttgcctaca agatgaaatc
    17761 cgaagccatg aagcggcagg gtttccgaac agatttaacc tcgtcacaag ttgggacgaa
    17821 gttgcggacg gacgataaag tggcacaggg cttcggcgtt ggcaggatga ccgtgcagag
    17881 atttatccga ttaacggaac tgataccgcc tattttgcag atggtggacg aggggaaaat
    17941 cgcccttacg cctgcggtgg agctgtcctt tttgaagaaa ggcgagcagg aaaacctatt
    18001 cgccacaatg gagagcgagg aagcgacgcc ctcactctca caggcacagc ggatgaaaag
    18061 cctaagccag agcaggcggc ttaacatgga cgctatcttt gcgattatga cggaggaaaa
    18121 gggaaaccag aaagaaaccg tgaaaatcgg catggagcgg ttaaagaaat acttcccgaa
    18181 aggaacaacg ccgaagcaga tggaggacac catcatcaaa cttttggagc gtgaattgca
    18241 gaggaaacgg ggcagggaca gccgctaatc ttctcttttc ggagggtaaa tacaaggaac
    18301 tggacgtaag aaaggtcaag gcaataagac cagaaagggg caggaaatga aagaaatcca
    18361 gtatgagatt gtaaaggaaa ttgccgtgtt gtctacgagc gaaagcggct acacaaagga
    18421 aatcaattta atctcatgga acgggaaaga gccgaaatat gacatccgca gcttttcccc
    18481 caaccgtgag aagtgcggaa agggaatcac gttgaccgct gatgaagcgg cggctctcct
    18541 taaagcattg caggaagaat tgaacagcgg ggattgattg tgtctgattg gcagggcggg
    18601 agcattttta tatactcccc tgccctgtct ggaaaggaag aattgagtat gggcgaggat
    18661 aagaaagcga acaaaaagag aaagcgcatt gtggcaagac agccagtgca gatgattgtc
    18721 agccgtgaat atgtcggcac acagaccgtt gccgaagcgt tcatcccgat tatctccgag
    18781 gacatccgca ggaagattgc cgaaggtgac accttcgaca atgaggatat atccgcttag
    18841 aatgtacgca atggaacatg aaaacagtta gggcagatac ggaggtttta cagtatggca
    18901 ggaatcaaag aagaaaagaa aatctattca gtcggcattt actgccgctt atctaaggat
    18961 gatggcacgg aaaacgagag tgcgagcatt gccacacaga aatccatcct cacggattat
    19021 gtgaaaaagc agggctggca tctggcaaaa acgtatgtgg acgacggtta ctctggtaca
    19081 aatttccaaa gaccgagttt ccagaacatg attaaggaca ttgaaaacgg gctgataaac
    19141 tgcgtgatta caaaggattt atcccgtctg gggaggaatt atcttgactg cggactatat
    19201 ctggaagtct ttttcccaga aaataatgtg cggtatatag cggtcaatga tggcgttgac
    19261 accttaaata aatcggcgat ggacatcacg ccgttccgca acatcctaaa cgaaatgtat
    19321 tcagccgatg tgtcggtcaa gataaaatcg gcatatcgag cgaggtttca gcagggaaaa
    19381 ttcatgggga catatgcacc ctatggctat atcaaagacc ccgccgacca caaccatttg
    19441 ctgatagatg ataaggtggc gcacgttgta agggagatat tcgaccttgc attagcggga
    19501 aatggacttg caaaaatccg caagcacatc aacagtcagc atattttacg ccctgccgct
    19561 tatgcggcgg agcagggggc ggcaggctat gaacggtact ttgagggtaa tgaggagaac
    19621 cgctatattt ggagcgagaa cagcgtgagg ggcattttga gaagcccaat atatgcggga
    19681 aaccttgcag gctacaagcg gattgccgcc aacatgaaaa gcaagaaacg cccctctaag
    19741 ctgcccgaag aatgggaagt gatacccgac acccatgagg ggatagtcac gcaggaggaa
    19801 tttgatattg tccaacagct tatgacgagc cgcagacggg aaaagaataa gggcggcttt
    19861 gagaatattt tttcaggcgt tatcaaatgt gcggactgcg gctatgctct gcgggctatg
    19921 agtgcaaaca ggaggaaacg ccccgacatc atcgactgca tacaatacac ctgtaataat
    19981 tatggcaggt acggcaacgt catgtgtacc gcacacgcca ttgaagcgag ggacttattc
    20041 aacgccgtcc ttgcagacat caaccgtttt gcggatatgg cggtgaatga cgagcgggcg
    20101 gtaagggcga ttgagaagcg gctcacggaa acagaccaga gcaaggcaaa ggcgatggag
    20161 aaagaacgaa agaagctgaa taaacgcctt gcggagcttg acaggctgtt ttcctctctt
    20221 tatgaggata aggtcatgga gcgtatcacc gagcggaatt tcgagatgat gtcggggaaa
    20281 taccagaaag aacagcttga aatcgaagcg agattaaaag aggtaacgga aactcttaac
    20341 gaaagctatg agaaatcgca gggaatccgt gacttcctct ccttaatccg caactatcaa
    20401 ggcttaaagg aactggacgc aacggttgta aatgcactga tagacaagat acttgtttcg
    20461 gagcgtgaga aatcagcgga cggaacagtg aaacaggaaa tcaagattta ttataaattc
    20521 atcggctttg tcggtgaatt acatatcaca cctacaaaac ggtggacagc gttacccgct
    20581 aaacactgta cggtgtgcgg cattgaatac gtccccggct ctggcatatc aaagtattgc
    20641 cctgcttgtg ccaagaagat acagagggag aagtcaaacg agagcaaacg caggagcagg
    20701 gagcagaaaa ggatggcatg tattgaactg tccgcaaaaa atgaccgact gatatggtgc
    20761 agaaagaggg atacatacct ttcacttcat agagaaaggg ggtatgattt tgaaaccatc
    20821 agacttccaa aagacgatac agtgtcagtt ggactgtaag ctcaaaaagg ttgtgaaagg
    20881 cagtgtccgt aactaccgca aggaattagc cagatgacag gcaaaggaag tacccttttg
    20941 tgagcttcca gaaattgtta ttgagaaatt gattgtctgg gatgattacg aaagtgacta
    21001 tgcgacattc gatgtgtgca gtacggaaat ccgtgtgctt gatgaagaac ttgaaaaata
    21061 caggatatat cggcatttac caacttatga aaagataatc agaaatttag tgtattttta
    21121 taataaaaat ataatgtttg tatacaaaaa tattaaagac attttagtaa gttttgtata
    21181 taagcaaaca tgtatttttt aatatagt
//
LOCUS       DAEPXW010000069        20900 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.070, whole genome shotgun sequence.
ACCESSION   DAEPXW010000069 DAEPXW010000000
VERSION     DAEPXW010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.070"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            81..902
                     /locus_tag="KRM55_002536"
     CDS             81..902
                     /locus_tag="KRM55_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBH1594759.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            923..2119
                     /locus_tag="KRM55_002537"
     CDS             923..2119
                     /locus_tag="KRM55_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBH1594760.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            2286..5684
                     /locus_tag="KRM55_002538"
     CDS             2286..5684
                     /locus_tag="KRM55_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH1594761.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDMGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYSSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            5694..7367
                     /locus_tag="KRM55_002539"
     CDS             5694..7367
                     /locus_tag="KRM55_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH1594762.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            7640..7834
                     /locus_tag="KRM55_002540"
     CDS             7640..7834
                     /locus_tag="KRM55_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBH1594763.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    8003..8236
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8313..9710
                     /gene="asnS"
                     /locus_tag="KRM55_002541"
     CDS             8313..9710
                     /gene="asnS"
                     /locus_tag="KRM55_002541"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBH1594764.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(9883..11058)
                     /locus_tag="KRM55_002542"
     CDS             complement(9883..11058)
                     /locus_tag="KRM55_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1594765.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            11477..12841
                     /locus_tag="KRM55_002543"
     CDS             11477..12841
                     /locus_tag="KRM55_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1594766.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            12863..13354
                     /locus_tag="KRM55_002544"
     CDS             12863..13354
                     /locus_tag="KRM55_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1594767.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            13627..14298
                     /locus_tag="KRM55_002545"
     CDS             13627..14298
                     /locus_tag="KRM55_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBH1594768.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            14383..15249
                     /locus_tag="KRM55_002546"
     CDS             14383..15249
                     /locus_tag="KRM55_002546"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBH1594769.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            15282..16784
                     /locus_tag="KRM55_002547"
     CDS             15282..16784
                     /locus_tag="KRM55_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH1594770.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            16914..17366
                     /locus_tag="KRM55_002548"
     CDS             16914..17366
                     /locus_tag="KRM55_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBH1594771.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DVFVNIVEYRTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEEGDFL
                     PLDGKNNGYVELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            17526..18329
                     /locus_tag="KRM55_002549"
     CDS             17526..18329
                     /locus_tag="KRM55_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594772.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            18387..19274
                     /locus_tag="KRM55_002550"
     CDS             18387..19274
                     /locus_tag="KRM55_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH1594773.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            19293..20141
                     /locus_tag="KRM55_002551"
     CDS             19293..20141
                     /locus_tag="KRM55_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1594774.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            20204..20893
                     /locus_tag="KRM55_002552"
     CDS             20204..20893
                     /locus_tag="KRM55_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1594775.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
BASE COUNT         8196 a         2221 c         3755 g         6728 t
ORIGIN      
        1 ttgtattatt atttttatat caaaaatagt aataaagtct atatacattt agaaaatact
       61 gtttaaaagg agtaggattt atgataaaaa aagagatatc taactttaga ggaagtagtg
      121 attatgtagt atcaccagaa ttgatggcat cagttaatgt tgctattgct cttgaaaagc
      181 cacttttgat taagggcgaa cctggaacag gtaaaactat gctagcacaa gcaatttcaa
      241 atgaattaaa aaaagattta gtaatttgga atataaaatc aactacaaaa gcacaagaag
      301 ggctttatgt atatgatact gttcaaagac tttatgatag ccaatttgga ggagaaggtg
      361 tagatgatat tagcaagtac ataaaatatg gtaaactagg agaggccttt agctcaaatc
      421 aacaagtaat tcttttaata gatgaaatag ataaggcgga tttagaattt ccaaatgact
      481 tgctttggga attggataaa atggagtttt acataaatga gacaaaagaa actgtaagag
      541 ctaaacaaag accaatagtt attataactt caaatgcgga aaaagaactt ccagatgctt
      601 ttttaagaag atgcatattt cattatatag aatttcctga tagagacatg atggaagaaa
      661 tagttaaagt acattttgat aaagtagaag aacacctatt ggaacaagta atgactactt
      721 tttattggat tagaagttta aaggacatac aaaaaaagcc tagtacatca gagttaatag
      781 actggataca agcattaact ttgagtggaa tgcctattga aaaaatagaa aaagaagttc
      841 cttttgcagg aatactactt aagaataatg aggatattga atctatgcaa agacacttat
      901 agttaatagg agctggataa ttatgtttat tgaatttttt tatttattga ggtcaagagg
      961 attaaatgta tctttaaatg aatggatgac tttaattgaa gcattggata aaggactgtg
     1021 ctattcaaac ttttcaaatt tttactatct ttgcaggatg attttaataa aaagtgaaag
     1081 tgattttgat aagtttgatg cagtgttttt ggagtatttt aaaggtatag aacaccaaga
     1141 agaaattcca gaagagatta tgaattggct taaaaaacca gatatagatt tagaagagtt
     1201 tgaaagatta gaacaaaatc caaatataaa tcttgataaa ttaagagcta aattggagga
     1261 acgaataaaa gaacaagatt ctcctcataa tggtggtaat tattggatag gcacaggagg
     1321 cacttcagag ttaggacatt caggaaaagg gcaaactggt atacgtatag gtggaaattc
     1381 tacttatggt agagctgttc ttgaagttgc aggagaaaga aaatacagag attttagaga
     1441 tgatgaagtt ttaaatatgc gtcaatttca agttgcacta aagagacttc gtcaattttc
     1501 tactagaata gatgctccaa agacagagct tgatttggat aagactattg aagagacttg
     1561 taataatgca ggatatttaa agttattttt tgagaagcca agaaaaaata cagtgaagct
     1621 tttattgctt atggattcag gtggttcaat gagagggtat agcactttat gtaatacatt
     1681 atttcagtct gtaagtaaat caaatcattt taaagatgta aagatatatt atttccataa
     1741 ctgtatttat gatagattat ttacaacacc tgaatgttgg ttaagtaaat ctattaatac
     1801 tgaatggata ttaaaaaata tagataaaaa ctataaagtt ataattgttg gagatgcttc
     1861 tatgtcgcct tctgagttgc ttcatattgg tggtaactat cgtggtccat ataattacac
     1921 acctggtata gagtggctta aaaggtttaa gagaaagtac agtaaaattg tatggatgaa
     1981 tccagaactt agagatggat gggattcaat taattattgg tatcaaactc aaagaatgat
     2041 acaaagtgaa tttaatatgt ttccattgac tgtaaaaggt cttgagaaag cattgaaaaa
     2101 tttaatggtt tcaagataaa gtaaatataa atgatggtat gatttattca aaattgtacc
     2161 atcattattt atttttttaa tatatctatt ataaattgta taactgaaac ttaaaaaatt
     2221 atatagtcta atacatttta gactcacaca aaacatatac attaataata attttagaag
     2281 tcgaggtgat tataataaat tatgaattaa ttgtaaaata caatggagat atattgaggt
     2341 tagaagaaga attaggtgta tcagtagaga tacttaattc atcatatgca ataataacat
     2401 caagtaatga agaagatgta aatatacttt taacttatcc agaaattgaa tttatagaaa
     2461 agccttttat attacagact caggatgtgc aaagtttttc aagtacagga ataacaggat
     2521 ttaaaaatag aactggttta actggaaaag gaactataat tggtataatt gattcgggaa
     2581 tagattatac tctacctgtg tttagagata gtgatggaag gtctaagata ttatattatt
     2641 gggaccaatc tattcaagga aatccaccag aaggttttag agaaggaaca ttatatacta
     2701 atgaagatat aaataatgca atagatggaa gtatgtatat acctatttca acaactagct
     2761 tacatgggac acatgttgca ggtatttgtg caactattgc aagtgatgcc agaataatag
     2821 tggttagagt tggaaatata cagaccgata ttttttcgag aagtacagag tttatgaggg
     2881 caattaaatt tattttagat agggcattag aattaagaat gcctgttaca ttaaatataa
     2941 gttatggaag taatgaaggt tcacatagag gaacatcttt atttgaacaa tatatagatg
     3001 atatgtgttt attttggaaa aacaatatag ttgtagcagc tggaaataat gcagataaag
     3061 gaggtcataa aaggattagg cttcaaaata atattacaga agaagttgag tttatagttg
     3121 gggaaggaga gcgtatatta aacataaata tatggccaga ttttgttgat gattttagtg
     3181 tacatttggt aaacccatca aataatcaaa cacaagcaat ctctctaact tcaggtgaga
     3241 taaggaatac tttgggtgaa actagaataa ctggttattt ttaccctata gcaccgtatt
     3301 ctctcacaag aagagttact ctacaattaa gttcaaatac acagataact cctgggttat
     3361 ggaaaattgt atttgaacca atagatatag taactggtaa tgtaaatata tatttgccaa
     3421 cttctgaagg tctaaataga aatactagat ttctgattcc tactcaagag cttactgtaa
     3481 cagttcctgg aacagcaagt agagttataa cagtaggtag ttttaattca agaacagata
     3541 tagtatctat attttctggt gaaggagata cacaattagg tgtttttaaa cctgatttat
     3601 tagctccagg tgaagatata gtatcttttt taccaggagg tacaagtgga gcattaactg
     3661 gaactagcat ggctacacct catgttacag gggtttgttc attgtttatg gaatggggaa
     3721 ttgtaaatgg aaatgattta tttttgtatt cacagaaatt aagggcatta cttctaaagg
     3781 gagcaaggag attaagtaat caatcttatc caaataattc atcaggattt ggttttttaa
     3841 atttatcaga tatagatttg tacactctat ctaatataaa tcaagattta gaaacagagg
     3901 atatgggata tagaagtatt aataagtcat ttaaagatga ggaaaatagt tataagttta
     3961 tagatggtta taatatgcaa atacataatg acttagagaa tgaaatttat ataagtaaaa
     4021 atgcaagtag acaatcagga atactatcag gaatagatat agtccatact cctgaatttg
     4081 aagaagaact agctgggtta ggtatgagtc aaaggttttt taagataagt gattcattag
     4141 gtgtactatc tataaataat acagactata gtagtataca acgagttttg caacttcctt
     4201 caatcataag aactgtatcg actacaaaga tgacattact tggagaaatt aatcgaggta
     4261 cttttggagg tgtagttgca acagaagaaa tgggcgtaaa tttctttaaa aataatccta
     4321 atattaatat aacaggaaga gggactctaa tatcaattgc agatacagga atagactatc
     4381 tacacccaga ttttatttat ccagatggca cttcaaaaat agtatattta tgggaccaaa
     4441 caaaagaagg aactcctcct gatggttttt atattgggac agaatataca cgagaagata
     4501 taaatcgagc tatcgcagaa aatgacccta gtctatctca ggatgaagtt ggtcaaggaa
     4561 ctatgttgag tgggatatgt gcagggcttg gaaatgtaaa tagtgaatat gcaggtatag
     4621 cagaagattc tgagctaata ataataaaac tcggcaagat agatgatttt tataatagtg
     4681 caatgttgtt tgctgcatct cagtatgcat ataaaaaagc ttttgaactt ggaagaccat
     4741 tagttataaa tatgtcttta ggtaccagta gcctagcagg tttaaccaat aggagtaata
     4801 gtgaaaaagc gttctttact agagggttat gtataacggc aggagcagga aatgagggta
     4861 atacacagac acatacatct ggaataatac catatgttgg aggttctgtt gaagttgaat
     4921 tagagttaaa tgaagacgag gaagaattat cattagaact ttggttaaat agaccagata
     4981 aagctgatgt aataatagta tctcccactg gtgaagaaag taaaagtgtt ggaatttcaa
     5041 attataataa agtaacaggc ttatttgatt tagaggggac tgaatattct ataacatata
     5101 tatacccaac aactttttct ggacagcaat ttactaatgt tactttaaag aatgcaaaaa
     5161 gaggtgtatg gaagattcga ttagtaggag tttatattat aacaggaaga tataacttat
     5221 accttccaaa tagagaactt ttaaaaagtg gaactagatt tagagaggta gacccttttt
     5281 acactataaa ttatcctgcg attcaagatg atttaataac cataggagcc tacaatacta
     5341 ttaatggtag tttatggcaa agttcatcaa gagggccaac tattgaagac aggttaaaac
     5401 cagatatagt agcaccaggt gtcaatataa tagctgctta tcctgggaac acgtatgcaa
     5461 ctataactgg tacagcagca gcaagtgcac atgcagctgg tgctgctgca atgtattttc
     5521 aatatacttt tgttgacggt agatatccaa accaagcata tgtgcaaaaa ataaaaactt
     5581 ttatgcaagc tggtgctaga aaagattcaa acacagtata tccaaataca aattctggat
     5641 atgggctctt ggatgttaga ggaatgtttg atgttttaag ataggaggga tttatggaaa
     5701 aatcttattg tataatttat caaggtgata tagaatctgc cctacaagaa aatggaataa
     5761 ataggtatat ggttttaaat agtcagcttg cagtaatata tgtaccttta gattttgatg
     5821 aaactatttt aaataatata atacaagttg cttggtggga agaatctgaa ccaatgagca
     5881 gtctaattga aataactaat aatgtaaata atggagaaac cattacaaca gcagctgaaa
     5941 ctgattatat ttatgaaaat ccatataatg atataacagg gagaggaatt ttattagcag
     6001 ttatagattc tgggatagat tatttgcatc ctgattttat aaatgatgat ggaactagta
     6061 aagttttata tttatgggac caagaagcaa atacaaatcc acctccagaa ggttttattt
     6121 ttggaagtga atttacaaga agtgagttaa atatagccat aaatagaaat gatgggagtt
     6181 tgagtcaaga taatataggt actggaactt tagtttctgg tatattagtt ggaaatggaa
     6241 ggataaattc tcagtacaga ggtattacta cagaatcaga cttaatagta gttaaattaa
     6301 aatcatatac agatacttat tatgctggaa ggataaatta cagtgtttca gattttttag
     6361 cagctataac gtatgttact aacatagcaa gaacagaaaa taaaccactg ataataaatt
     6421 tgactattgg agttaagtca agtgctgtag caactacttc aatactagat acttttaata
     6481 tattgagtag tgctggtgtg gtagtagtga gtggtgcagg aaatcaaggg aatacagata
     6541 ttcattattc tggcagattt agcagtgtgg gagaagttca agatgtaata atacaagatg
     6601 gagatgacta tgctcttgat ataacactaa atacgaatgg tccagataaa gtgggagcac
     6661 agataatatc tccttcaggt gaagttagtc atgatataag gtattctcca gacttttata
     6721 tatatagagg aaaatttaac ttagaaaata ctacttatgc aatgagattt atttatccat
     6781 atattacctc tggaaaagaa aatttggaga taagattaag agatataaaa cctggagtat
     6841 ggattttaag attgacttca gaacttataa taaatggaga atatgacata tacttgccaa
     6901 ataaaaattt gatagctcca gacacaaggt ttttagaccc tgattcagta gctactataa
     6961 ctatgtatgc tgctagtgat gatgtaatta cagttggtac atttaacaat aagactgata
     7021 gtatgtggat tggttcttcg aaaggaccaa ttagaggaag aggaattaag ccagatatag
     7081 tagcttcagg tgtagatata atatccacat ataaaaatgg aacatataat acaggaacag
     7141 gaacaggagt gagcagttct atagtcacag gtgttttagc cttattgatg gaatacttag
     7201 aaaaacagga taatgtaccg agattatcat tgtttacaca agttttaaaa acatatttaa
     7261 tattgggtgc tacaaaactt gagatatata catatccaaa tgtatcgcag ggatatggga
     7321 ttttaaattt aaaaaatacg attcaacaga tagcaaatac tctatagata agaacctatg
     7381 taaaattata attgattatt agtttaattg tatcaaatac tttagataga gtagaaaaat
     7441 agcataaaaa ataaatatga aaattaaaaa acagttttat attttgaata cacaaagtaa
     7501 atattttgta tataaatagg tataaattaa gtattgaaaa gatatgatgt taatttaaaa
     7561 ataattataa tttagactta tgaattttat ttgtaaaatt gctaaaacta ttacaaaata
     7621 aataatagag gtgatagttt tggaaagtaa aaaggcaaga gcattaaaag gtaaagataa
     7681 taaaagactt aaaagttcac ttttagttgg aaatgagtcg acagcagcat gggctgatgt
     7741 tgaaaaatta aaacctcata gtaaagtttc aataccttca attaagggtg tcgaagaagc
     7801 aaaagactgg gttgacaatg gaagtaaatt ataaaatttt ggaaattgaa gtaataaaga
     7861 agtaatgaag ataagtattt attgtcatta tgtaaggtag aattattata ttttaaataa
     7921 caatcagtat caattatata aatttattga ctaaaaattt ataaattggt ataattttgt
     7981 taattagcag aaataataaa agataaatac tgtgaagaga agagtagata taaaatgtag
     8041 ttctagcgag ttgaggatgg tgaaagctca atacgaggtt tatattgaag aacatcttgg
     8101 agtttctaat cgaaagctta tttagtaagt agacttagac ggaaggcacc gttataggct
     8161 ttaagcattg cttaactaag aggtcattat gacaactagg gtggtaccgc gagagtaata
     8221 gtctttcgtc cctttatata gggatgaagg gcttttttta ttgaaattat atttaaaaga
     8281 aattaataac aattatacta ggaggattta aaatgcaaaa ggaatttata acagtaaaag
     8341 aattgtacag agaaaaagaa cagtacatag ggaagactgt aaaagtagct ggatggataa
     8401 gaacatctag agtatctaaa aattttggat ttatagagct aaatgatgga agcttcttta
     8461 aaaatatgca gatagtattt gatgagaaag tagaaaattt taaagaggta ggaaaattag
     8521 caataagctc atctatactt gtagagggag agttagtatc tacagaaggg gctaaacaac
     8581 cagtcgaaat acatgcaaaa agcatagttg tagaagggga atcagatagt tcgtatccac
     8641 tacaaaagaa gagacatacg cttgaatatt taagaacgat agcacattta agaccaagaa
     8701 gtaatacttt ttcagctgta tttagagtaa gatcaatagc tgcctatgca atacacaaat
     8761 tcttccaaga aagaaacttt gtatatgcac attctccaat cataacaggt agtgactgtg
     8821 aaggtgcagg agagatgttt agaataacaa ctatggattt aaatgatatt ccaaaaactg
     8881 aagatggcaa aatagactat actcaagatt tctttggaaa agaggctaat ttaacagtta
     8941 gtggtcaatt aaatgccgag ataatggcac tttcttttag aaacgtttat acttttggac
     9001 ctacatttag agctgaaaac tcttatacag gaagacatgc ttcagaattt tggatgatag
     9061 agccagaaat agtttttgca gaccttgaag ataacatgga acttgcagaa gatatgataa
     9121 aatatgttat aagctatgta ttagaaaatg ctcctgaaga aatggaattt tttaatagtt
     9181 ttatagataa aggattgtta gaaagattaa ataagatagt aaactctgag tttattagaa
     9241 taacgtatac taaagcagtg gaattattaa ttgaatctgg gcatgaattt gagtatcctg
     9301 ttgagtgggg atgtgacctt caaacagagc atgaaagata tataacggag caaatatata
     9361 attgtccagt gtttgttaca gattatccaa aagatataaa agctttctat atgagaatga
     9421 atgaagatgg taaaactgtt agagcaatgg atttactagt tcctggagtt ggagaaatcg
     9481 taggaggttc tcaaagagaa gaaagagaag atgtattgtt agatagaatt aatgaaatgg
     9541 gattaagaga agaagattat tggtggtatt tagaacttag aaagtttggt actgctactc
     9601 actctggatt tggtcttgga tttgaaagaa taattatgta tatgacaggt atgtctaaca
     9661 taagagacgt tatacctttc ccaagaactc ctaaaaatgc tgaattttaa taattatata
     9721 taataaaact tatataactt taagtataaa cactaaaatg acttgcatat ttatctattt
     9781 tagagatatg caagttattt ttattgtact ataaatatat aatttgatta cttttatttt
     9841 gcgatataat acttataggt ttatgtaata gtatgtaacc ttttaataaa atgcaacaca
     9901 attacgtcct tgttcttttg cagtatatag ggccttatca caattactta taaactcatt
     9961 taatgttatt gtctttccaa ttttctttgt ataaactcca atactaacag ttacacattt
    10021 taaaggaaca tcatcacgct caaaattgca ggactctata atttttcgta aacattctga
    10081 tttaagttta gcatctgcct cattacagtt aaaaatacat ataaaaaatt cctcaccacc
    10141 atatcgtata gcatgttcat tttcagaact tgtaaaatct aaaattactt tggcaatatt
    10201 ttgtagacaa tagtctccct tttgatgtcc ataattatca ttaaattgtt taaaataatc
    10261 tatatctatc atcattccag ttataggttc ttgatttgca tggctgatta attttttttg
    10321 tagaatatct tcaaggtatc tacggttgtt cattttagta aggtcatctg tcataacttt
    10381 gtcgttaagt aaattattta tatgagatat ttcttcatat tgttgactaa ttaaaagttt
    10441 atcatagtaa gtaaatacac gatttctata tagcattgta gaaacaaaaa tggcaaggga
    10501 tgttataaaa aatgtgttga caatattact aaactcattg cctggtatag tttgaatccc
    10561 aggtaagaat aaattaagaa acaaaaagca tcctccaaaa actattactg attctccaaa
    10621 ttttaatact gagaaagctg cagctgctaa cataatataa ctaaatacac ttaggtcatt
    10681 tccacctaac tggtcaagta gagtaattac acaaccccat aggcagaaaa aagtcacata
    10741 aattatccat aaatttatat aaaacgtaca gcaatccttt tttttattcc aaaggtaaga
    10801 aaatacaaac ataaagacag aagatacaca aaatagtgtt acatacatat aaaaatacca
    10861 ttggcgtctt ggtgtgacaa aagggcctcc ttctctagct gagattgata tcatcataat
    10921 tatttgagat attactatta ttatgcaaat gattttaccc gtatgataaa gataattgca
    10981 gagttctttc tcaacattgt ctttgtgttt tttgtctaga ggaaatccaa aaaatttttt
    11041 tattttttct aagttcatat aagcctccat taaaaataaa gcataaaaat aagtattcct
    11101 ttctatcatt agatatttgg aatacttcgt ttatgattta attatatcaa aatatattgt
    11161 gtgtaacaat ctaaaattgt gatagataaa atttattaga taatgtcgag taactttatt
    11221 gattaatact ttattataat taagatttac agatagttta ctactgaaaa taaagaatag
    11281 aataaattta aattaagcat aataaaatat aaataataaa gttcgcatta acaaactatt
    11341 taaatatcaa gaactgttaa aaaacaacag caataaacaa ataaaataga taaatatatc
    11401 caattaaggt ataattaagt tttatatgat atagttatat ttgataattt acaatagtaa
    11461 aacttggagg gaaaaaatgg gtgaaaagaa aataaataat atgaattatt cacataataa
    11521 ttattccaaa aagacaggtg aaccaactag aaaaataaaa aatagccata tcactcttaa
    11581 aagtaaagaa gaaaaaattt gttctagttg caataaagaa aataatacta aggataatta
    11641 ctgtaaattt tgtggaaatg aactttatga aatagcatca ttaagaccac ttgaaacaaa
    11701 actagacttg aaatctaaaa taaaagagct ttcatatcat gcaaataaaa gaggtgtatt
    11761 tttaacaaca tttacaacca tatttatatt gtttattatt gcattgatat ttaaagctat
    11821 tataactatt caatttaatg atattagtta tttagtaaat ccagcacata taatcctagc
    11881 tctcaacttg ggtcaaatta gtgtatctat gtctaccatg atgggttctg ggtttataaa
    11941 tgccaatata ggtttgttga tattacttat aatccctatt ttggtattat taatatcaaa
    12001 cctaattttt atgagaaaaa gatgtagaga ttcaaaaact gtattagcaa attctctagg
    12061 agttggaatt ttttatggat tagttttagc tattttatct atttttacta atgtaaaaac
    12121 tagttcacat agtatgttag aatatggata tgcattagaa tatagttatg aattttttag
    12181 tgttctttta aatggattcg tattagggtt tatatgtaca tacataacta cttataaaaa
    12241 aagttatgaa aaagaaaata tgtatttatc tcttttttca aattctataa gaacattcat
    12301 attaggttat gttttagtat tagtaatact attggtacta actatatctg atagtagtta
    12361 cttaaatgaa ctagatatga gtagttattc aaatggatta aatttattta ctatactccc
    12421 acaaatagct agttatatgt gggcttttgc aaatggaatt tcagtaacca taataaactc
    12481 aacagtatca atgtttactt taagttcttc atctttattt ggagatacta aattaatgtt
    12541 ttatgcaatg ggagcattgt ctatgttaat attattatta aatggataca agctaagatt
    12601 taagtataat acagatagta taagacctat aatagtattt agtatatatt atgcattttt
    12661 gatgggaata ttggctttat ttagtacatt tatactagat agtaatatta atttctttaa
    12721 tacaactaat tatggaacaa ctttaataat gcaatttaaa gtcttacaag ctattgtaat
    12781 ttcatttgta tatagttttg tgatatcttt aataggatat aagctaaatt cagctgatta
    12841 aatatgattg gagggaattt ctgtggaagg aaatactaat aataaagtag atgataaatt
    12901 ttctaaggtt aagaaaaagt ttggtagtgg aaaatttaaa gttgaattat ataaagaaaa
    12961 atcaaaatta aatagagaga ttgatgatat tcaagaaaag aaagcaaaga tattcttgga
    13021 aatgggaata ctgacatatc aaaaaattag agaagattct attaatgata atagttttga
    13081 taaattctgt gatgagttac tagaacttga taagttaatt tatgaaaaaa atatggaaat
    13141 taatgaaatg gaaatggcag aaagtaatgt aacttgtgag tgtggttatg ttggaaatgt
    13201 aaatgataaa tattgtgctg aatgtggtaa aaaatttgaa ttggaaaatg aatgtgatga
    13261 ttttataatt tgtggttatt gtgaaagtga gatagataca gaggctgaat tttgtccatg
    13321 ctgtggaaga aaaattataa tggatttaga ataatattgg gaaacctatg tatagtatac
    13381 atgggttttt ttattgaaat tatttaaatg gacttataac agtagttata taaaatgaaa
    13441 ataaacacca aaaaaatgaa ataaaatttc ttttaaatgt aaaaaacaag ctaatatata
    13501 aaataaatca gtaaaaatat agatgcgaga aaaaaatatg aaaaaatatt gcaaagaaaa
    13561 agttttcatg ttattattaa tacataaatc aagaaaataa atttcagaaa cgaggtaatt
    13621 taaaaaatgc tagataaggt aaagggaaga ttaatagtat catgccaagc tttagaagat
    13681 gaacctcttc atagtccttt tataatgggg agaatggcta aggctgctat ggaaggtgga
    13741 gctgttggaa ttagagctca aggagttgaa gatattattg aaataaaaaa agttactgga
    13801 cttcctgtta taggtattat aaagagaaac tatgaagatt cagatatata tataacgcca
    13861 actaaaaaag aagttgatga acttttaaca acagggtgtg aaatgatagc attagatgct
    13921 accaatagag ttagaccaaa taatgaagac ttaaaagaac ttataaagta tataaaagaa
    13981 aacggtgttc tagtaatggc agatatttca aattatgatg aggctatcaa agcacaagag
    14041 tacggtgtag attgcgtttc aactacacta tctggatata ctccatatac taaaacatta
    14101 gaaggtccag attttgtatt aatggaaaga ttagttaaag atttagaaat acctgtaata
    14161 gctgaaggaa aggtaaatac tcctcaagat ttaaaaaagg tctttgagtt gggtgttcat
    14221 tcatcagtag taggttcagc aataacaaga ccacaattaa taacagaaaa atttgttaaa
    14281 gcaattgaaa ttaattaaaa attaatttat aaattaaaaa attattatat ttaactatat
    14341 ttgaaaatta aaattggagg taaagatatg agaacaacag atatgaaggg aatttattca
    14401 gcattattag tttcatttga taaggaagga aatataaatg aaaaagggtt aagacaaata
    14461 attagacaca atatagatgt ttgtaaagta gatggtcttt atgtaggagg aagtacaggg
    14521 gaaaacttca tgctttcaac tgatgaaaag aaaagaatat ttgaaatagc taaagatgaa
    14581 gtgaaagaag aaataaaatt aatagctcaa gttggttcag ttaatttaaa agaagctgta
    14641 gaacttgcta aatttacaac tgatttagga tatgatgcaa taagtgctgt tacacctttt
    14701 tactataaat ttgattttga agaaataaaa cactattata atacaataat aaattctgta
    14761 gataatagat taataatata ctctatacca tttttaactg gtgttgatat gagtttagac
    14821 cagtttggag aattatttga aaatgaaaaa ataataggtg ttaagtttac agcagcagat
    14881 ttctacttat tagagagaat gagaaaaaca ttcccaaata aattaatatt tgcaggattt
    14941 gatgaaatga tgttaccagc tacagtttta ggtgtagatg gggcaattgg ttctacattc
    15001 aatgtaaacg gtgtcagagc tagacaaata ttcgaattaa ctaagaatga aaaaatatca
    15061 gaagcacttg aagtacaaca tgtgactaat gatttaataa cagatatatt aggaaatggc
    15121 ttatatcaaa caattaaatt actacttgaa gaacaaggtg ttgaggctgg atactgtaga
    15181 caacctatga aagaagcaac tgatgaaatg aaatcaagag caaaagaaat atacagaaag
    15241 tatttttaat aaaatacttt tagtatggga ggattagtca aatggtagga tttacttgga
    15301 tagattttgc aatactagtg gtttacttat tggcagtttt atttgcagga ttgttatttt
    15361 caaaaaagga aatgaaggga aaagagttct tcaaaggtga tggaactatt ccgtggtggg
    15421 ttacatcagt atcaatattt gccacattat taagtccaat atcattttta tcattagcag
    15481 gaaattctta tggtggtact tggattttgt ggtttgcaca attaggtatg tttatagcaa
    15541 tacctttgac aataaaattt ttcttacctc tatatagtag gttagaaata gatacagcat
    15601 atgaatactt agaaatgaga tacgaaagta aaggtcttag agtacttgga gctttgatgt
    15661 ttataatata tcaaatagga cgtatgtcta ttataatgta tcttccatca atagttctgg
    15721 ctggtcttac aggaatacct gtaaatgtac tgataatagt tatgggtgta atagcaataa
    15781 tttactcata tacaggtgga ttaaaggctg tcttgtggac cgattttata caaggaatgg
    15841 tattaatagt aggtgttaca gggacattgt tctatttaat agcaagtata aatggtggtt
    15901 ttggaacagt aatggatact cttacaactg gacacaagtt cttagcaagt aatgaagtta
    15961 tgtttgataa aaatatacta tctacaagtg catttataat atttgttgga gctggtctta
    16021 atactttttc atcatatgta tcgagtcaag acatagttca aagatttact acaacaactg
    16081 atataaagca acttaataaa atgacatatg gaaatggtgt tttatcaatg ggacttgcaa
    16141 cagtatttta tctaattgga acttgtttat ttatatacta tactcaaaac ccagatttag
    16201 ctcaaacagt tcaacaagac caagtatttg catcatatat agcttatgaa ttaccagtag
    16261 gtataacagg aatactactt gcagcgatat atgcagcatc tcaatcaact ttatcgacag
    16321 ggcttaactc agttgctaca agttggactt tagacataca aactatcata acaaaagata
    16381 taagtatgga aaaacaaact aagatagcac aatatatatc attaggtgta ggtatacttt
    16441 ctatagctgt tgcaatagta ttagcaaatg gagaaataaa gtcagcatat gaatggttca
    16501 atagttttat ggggctagta ctaggtgttt tagcaggaat atttgtactt ggtgcatttt
    16561 gtaaaaaagc aactaaaatg ggagcatatg ttggattcat agtatcagca attttagttg
    16621 tttatttaaa ataccgtatg ccagaagtaa cttcttgggc atattctcta ataacaatca
    16681 cgacttctgt agtggtaggt acaatagtta gtgcaataga agctaaagtt aaagcaaaag
    16741 tatctttacc aaaagctgag actactgttt attatgaaaa ataatattta aatgataaat
    16801 tgtcttatag agtgattaga taaataattt agttgctcta taagattgta taatatactt
    16861 tgtatataaa agtataaaaa tagactttat aattatatag ggagatagtg cttatgatat
    16921 ttggaaatat aaatcatagt aagacatatt caacattgca tgaagattta cttagatgtt
    16981 ttgaatatgc taaagataat tcattaatag attatgaaaa aggtacttat acaatagatg
    17041 gtgatgatgt ttttgtgaat attgtagagt atagaacttg tgaaaaagaa gatagattct
    17101 gggaagctca taagaagtat atagatgttc atttgatgct tgatggatgt gaacgaatag
    17161 atataaattt tatagaaaat ttagaacaaa aaatatatga agaagagggc gatttcttgc
    17221 ctcttgatgg taaaaataat ggatacgtag aacttagaaa aggtgatttt ttagtttgtt
    17281 atccagaaga tgctcatatg acaggaataa aagttttaga aaaagaaaat atcaaaaaag
    17341 ctatttttaa ggttttggtt agataatgat aatttatata accactaggg ctgaaaatag
    17401 tgatttaact ttcagcgatt agtgagactt cgtaaatttt agttagatta ctattttcag
    17461 ccttagtttt ttatgagaaa attgaaaata attaaaagct taaaattttg taaaggagtt
    17521 aacttatgga aaatatagat gtattcttat taataggaca aagcaatgct agaggattgg
    17581 gaaatccaaa agagagcatc attccaaatg aaaattgttt tgaatatttg agtactgatg
    17641 aaattataaa tatgagatgt gagctagaga cttcagaagg tgatggtact atagcacctg
    17701 cattttcaaa tgaatggaat aagcttactg gaaataaagt ttgttttatt cacaatgcaa
    17761 aagatggttc aagaataaaa aactggaatc atgataataa ctggtttcta aatgacacta
    17821 tagaaaaatt taatacaggc tgtactacct taagtaaaca ttataatata gaaaataaat
    17881 atgttatttg gattcaaggt gaaagtgatg caaaatatgg tagtgatgta ttgtactata
    17941 aagaaagtct aaaaaaaatt gcgtataggc ttaaagaaga atgtatgatt gataaaatgt
    18001 ttgtaagttt aactggttat tggcttggag aagatgaata ttttattaga acaagacgaa
    18061 ttgcagcagc acaggagtcg gcttgtagtg aatgtgatat attatgtgta ggaagcaaaa
    18121 ttgctatgca gtttcatgac agaggattaa ctattgatga tgttcattac actcaagaag
    18181 gtcttaatat gttaggagag gacttatgta aaaatattta taagtatcat ataaccaaag
    18241 aaaaaagtgt attaagtgat actatagact tatcagaagc aaggaaatat atctgtgaat
    18301 tggaaaagat aagtaaaaga tttgtgtaat ataaaatttt aaatagagtt gttaatttat
    18361 aaaaataatt tgtatggaga tatgttatga aaaattacgt ttgtatagat gttggaggta
    18421 cttcaataaa atatggtttt attagagaag atggatttat aattgataaa tcaagtcttg
    18481 atactgaagc aaaggaaaaa ggtggagaag gaatattagc caaaataaaa gatatagtaa
    18541 aaaaatatat agaggaaaat gaaataagtg gtatatgtat atcaactgca ggtatggttg
    18601 acccagttga aggtaaaata ctatttgcat tagaagaatt aattccaaac tataagggca
    18661 tgcaattaaa aaaagaagta gaaaaagagt ttaatataaa atgtgaagtt gaaaatgatg
    18721 ttaattgtgc tggacttggt gaaatgtggc ttggagcagg tagaggtgca acatcttcta
    18781 tatgtttaac aataggtact ggaattggtg gatgtattat aataaataat aaactgataa
    18841 atgggtttag taatagtgct ggtgaagtag gatatatgaa tgtaaatgga agttcttttc
    18901 aagaattggc atctactagc agtctaatta aaaaagtagc aaaaataaaa aatttgaatg
    18961 aaaatgactt aaatggaaaa ataatttttg atttagcaaa gaataatgat gaagattgtt
    19021 taaaagaact cgataatatg ataaaatcat tagcagttgg aatcgcaaat atatgttatg
    19081 taataaatcc agaagtggta attttaggtg gtgggattat ggcacaagaa aagttcctaa
    19141 aaccaaaaat agacaaagca ttaaaggagg ttcttataga gagagtttac aaaaacacta
    19201 atatagaatt tgcaaagaga caaaatgatg caggaatgct tggagcatta tataattttt
    19261 taaacaaaat ataaagaata gaagggtttt taatgagtat tttagaacaa ttggaatcac
    19321 caacttttaa agtcacaaaa tcagataaat tattaatagc ttatataaaa gaaaatatag
    19381 atgatgtatt ttataaacca atatcacaaa tagctaaaga gagcaatatt ggtgaagcaa
    19441 ctataactag gtttgtaaaa aaaatgaatt ttaatggatt acaggatttt aaagttactt
    19501 tagcacaaga aatatcaact atcaataaaa aaaatattat aaataaaaat atacaaaatg
    19561 atgagccagc tttggataca gcaaaaaaac ttttaagttc aaatgtaacc actttagaga
    19621 acacagtaga gataatcaat agtaaggatg tacatgactg cgcaaggctt ataataaatg
    19681 caaagaaagt ttacttcata ggtattggat attctggtat aatagcacag gattcaaact
    19741 ataaatttat gagaataggt cttaattgtg taagttttga cagtagtcat acaatgataa
    19801 tgatgtcttc cataatggaa gaaggagatt taataattgc aatttcacat tctggtgaaa
    19861 cagaagagat tataaaaact gtaaagcttg caagagccaa taatgctaaa attatatcaa
    19921 ttactgaaaa taaaaattct gaattaaagg atatttcaga tgtacactta tcttatgtat
    19981 cgggagaaac agtactggaa accggttcaa tatcttctaa attagcacaa tttttcatta
    20041 ttgatttagt atatacacag gtagtaaaag aactttctaa tgaagctatt gaaaggaaaa
    20101 ttaaaactac aaatgctata aaattgttta aaaatgaata aaataagaaa tttgtaatgt
    20161 tttatagagc tctcttaaaa atttaggaat ggagagatat tacatgtcta aattaaaaga
    20221 ttataatatt gataaagtaa taatttttaa taatttaagt actaaaacga agaatcaact
    20281 taaagaaaaa gttaaactaa aaagattaca aaaaaaagaa attttatttt atgaaaaaga
    20341 tagcttagac agtgtttata tacttttaga aggaaaggta tctattttta agataagtga
    20401 aaatggagag agaaaagtaa ttttcatatt aaatagtggg gaagtcataa atgatattac
    20461 acttgacgct tctaaaaact ctactgttgg ctgtgaagca tttgaaaatt caattgtagc
    20521 ttattatagt attgaagaat ttttagaaat tatgcaaaat gattttcaac ttacaaagga
    20581 tattatttct tatatggaaa gaagaataag acgtttatat agacagttga aaaattctat
    20641 atccataaaa gtagataaaa aacttgcagc aaaattatat aggttaagta gagaatttgg
    20701 agtttgctgt ggagaatgga ctttactaaa tgtaaatatt acagttacat atttagctga
    20761 tatgcttggc tgtaaaaggg agactgtttc cagaatgata aaggtattgc aaaaagaaga
    20821 acttattaaa attgacaata aaggttttta tgttaaagaa actgaattat caaggtattt
    20881 taaaaataat taattatgat
//
LOCUS       DAEPXW010000070        20523 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.071, whole genome shotgun sequence.
ACCESSION   DAEPXW010000070 DAEPXW010000000
VERSION     DAEPXW010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.071"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            93..1016
                     /locus_tag="KRM55_002553"
     CDS             93..1016
                     /locus_tag="KRM55_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1594776.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQDSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(1188..2330)
                     /locus_tag="KRM55_002554"
     CDS             complement(1188..2330)
                     /locus_tag="KRM55_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1594777.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(2348..4102)
                     /locus_tag="KRM55_002555"
     CDS             complement(2348..4102)
                     /locus_tag="KRM55_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBH1594778.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLATYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            4238..4444
                     /locus_tag="KRM55_002556"
     CDS             4238..4444
                     /locus_tag="KRM55_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594779.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(4449..5372)
                     /locus_tag="KRM55_002557"
     CDS             complement(4449..5372)
                     /locus_tag="KRM55_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594780.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(5626..7326)
                     /locus_tag="KRM55_002558"
     CDS             complement(5626..7326)
                     /locus_tag="KRM55_002558"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBH1594781.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(7738..8151)
                     /locus_tag="KRM55_002559"
     CDS             complement(7738..8151)
                     /locus_tag="KRM55_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH1594782.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(8217..10595)
                     /locus_tag="KRM55_002560"
     CDS             complement(8217..10595)
                     /locus_tag="KRM55_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH1594783.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASNTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKSGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            10914..12365
                     /locus_tag="KRM55_002561"
     CDS             10914..12365
                     /locus_tag="KRM55_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBH1594784.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(12569..15082)
                     /locus_tag="KRM55_002562"
     CDS             complement(12569..15082)
                     /locus_tag="KRM55_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1594785.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTSQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(15305..16126)
                     /locus_tag="KRM55_002563"
     CDS             complement(15305..16126)
                     /locus_tag="KRM55_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1594786.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSMYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(16645..17121)
                     /locus_tag="KRM55_002564"
     CDS             complement(16645..17121)
                     /locus_tag="KRM55_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBH1594787.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(17156..17734)
                     /locus_tag="KRM55_002565"
     CDS             complement(17156..17734)
                     /locus_tag="KRM55_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH1594788.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(17838..20438)
                     /locus_tag="KRM55_002566"
     CDS             complement(17838..20438)
                     /locus_tag="KRM55_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH1594789.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTAPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHYNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
BASE COUNT         6473 a         3670 c         2285 g         8095 t
ORIGIN      
        1 aaatatctat agtaaatact taactatact taaaaagcat ataaattgat ataattatat
       61 aatagataag ttaatattga ggagggataa ttatggaaat aagagtatta agatattttt
      121 tagcaattgc aagagaagaa agtatatctg gtgcggcaac ctttttacat ataacacaac
      181 caacactttc tagacaaatt atggaacttg aagaagagtt gggagttaaa ttattggttc
      241 gaggaaatag aaaaatcacc ttaacaaatg aaggtaggct tttacataaa agagcagaag
      301 aaattatatc attagttgat aaggttgaat tagaatttga caatcccaat gagattatta
      361 gtggtgatat atatatagga agtggtgaaa ctgaagctat gcgacttata gctagaactg
      421 cccatcattt tcatcaaaaa taccccaatg taagatatca cctttttagt gggaatgctg
      481 atgatgtgac tgaaaaatta gacaagggac tgcttgattt tggtatttta attgaacctg
      541 caaatataca gaagtatgat tatgcacaaa ttcctgctac tgatgtatgg ggtttactaa
      601 tgcgtaaaga tagtgccctt gcatcacaaa gcacaataaa tccaaaagat ttatgcaata
      661 tacctcttat tatttcaaga cagacacttg ttgataaagc aatttctaaa tggcttcaag
      721 acagtaatga aaaactaaac attattgcaa catacaattt agtttataac gcttctcttt
      781 tggtagaaga aggtctgggc tacgctctgt gtttagatag actcgtcaat actacagaaa
      841 acagtaatct ttgttttaga cctctatctc ctcctttaga agctaaatta aatattatat
      901 ggaaaaaaca tcaaatattt tcaaaggcag cagaaaaatt tttacttcaa atacaaaaag
      961 atttttcttc tatcatgttg gatacatcta agttggatac acctaaagaa aaataaatca
     1021 taataaaagg tgagagtgtc tcaaaatgaa ctttgcactg tataaggcac tcttttttat
     1081 acaaagtaaa atatatgttc atcatttcag cattaaaaaa gaggcttatc tctattttga
     1141 gatagcccca cttaaccaat aaaattaaat acaacttaac aatatcctta cttatttatt
     1201 ccaagttctc ttagacaagc aatagtaatt tcatcttgtg gatttaattc ataagctctt
     1261 tctatatagt aagttgcatc atcaatatca ccattattta aataagccat tcctaaattg
     1321 caaagtattt ctgggtcttc ctttatctta gccgcttgtt caaaatactc tattgcttta
     1381 tctaaattat tcttataagc ctcacaaagc cccaattcca ctatagtatc cacctgatta
     1441 ggctttatta tcaatatctt ctcaagatac atcttagcct gctctatttc gcccataccc
     1501 ttatatccaa gtgctatcat aaacagcaag ttccaccaat ccatatgttc ttcttctaat
     1561 ggaagtaact tctctaatcc ttccttaaac ttaccttgga atacaagtgt atatccttct
     1621 tcatattgaa ctttaaagtc catcttgccc agattctctt gtacctcagc tactaaatca
     1681 gcatctaacc ctagccttaa cgcttcttcc caagtcagct tagtctttaa atattgacct
     1741 tgattataat aatggtagcc taagtgataa taacctaatg caaaattctc atcaacatca
     1801 attacctttt caagcttagc catggcttca agtaagaatg cattcattgc cttatcatcc
     1861 atatcttttt gatactgttt agctatctct tggcaaacaa tcgcatagtt atacattgca
     1921 tctaaatcat ctggatacat tgttataaat gcttttatat atattaaaga atctgtatgt
     1981 tcaccaatct caaagtattt tctcgacata tatcccatat acgatttcaa atccaaatca
     2041 atatcttttg ataaagcatt taaaaacttc tcatactctg cattgttttt aaacttacta
     2101 tctattccaa ttatatatat cattgcatct gctatagaca ttgaatttaa cttatcttga
     2161 gcagtctttt cttttatccc ttttactaat acctcatttt ttataggtac atctaatcca
     2221 ccttttggca cttcatagct ttttaattta aactctccac catgttttat agttataaaa
     2281 gctaattctt ctgctttttt tagcaaatat ttttctatct taaaatccat tttatcctcc
     2341 taaatactta aatctctact ttatgagttt tagatttctc aaatattttt ttatcatcat
     2401 actcaaataa gactacattt tctacttctc ttatttctgt atttatatca ttttttaaat
     2461 ccacaacatt aaatctaaat ggctcaaaat gaacatattt tattatatgt ttagctggtt
     2521 tatcaacaaa actaggtaaa tatgttgcta agttatcatt atcttgtaaa aatacatggc
     2581 atctattctt aaaatcatcc acatctagct tattaaaaaa ctgtggtata tttgatgttt
     2641 tacccagtga tatatagtca tattttaata tatcattgaa tacatcatta tctatgttga
     2701 ttttttcatt atagaaatcc atcaatattt tatataactg attctttcct tgtgccaaat
     2761 caaagtagcc attttcatca aaatacttgg caaaaacctc aaagaattta aaagggcttt
     2821 gtttataaaa tctgcctata atatatctca tagataacac aaagttttta gaattgtagt
     2881 atctctccag tatatcttct atatccttta gcttcaaagt ttcttcatag cttatataat
     2941 tattgtataa aaactcatat ggagcataat ccttatattt aaaaccatgc tcatctgcaa
     3001 cttttctcat acctgtccct ttaatcatct ttaaaaagcc taattgcaga tgctctatac
     3061 ctagattaaa tacatcatta aaagaatttt caaagctctt ataatcttca taaggcagtc
     3121 ctgcaattaa gtctaagtgc tgatgtatat ttctataaga tgctacagtt tgtacaacat
     3181 gagacaactt tttaaaatca tcccttctgc ctactgcatc aagtgttttt tcattcgttg
     3241 actgaacccc tatttcaaat tgaaaaagac cttctttaca atcagccaaa aactcaagca
     3301 tcttatcatc tatcaaatac gctgtaactt caaaatgata agttgtatat ccattatcat
     3361 ttttcataag aaaatccatg atttccatag ccacttttct atttgcattg aatgtcctat
     3421 ctataaactt tatttgtgat actcttgcat ctattaaagc ttttaaatca ctctttatcc
     3481 tgtctaaact aaaatacctt agacctggaa tagtagatga taaacagtat tggcagttaa
     3541 aagggcaacc tcttgatgat tcataataca ctattctatt ttcatattct tttggattca
     3601 agttttcata aggactagga atctcatcca aatcttgaag taattccata ggcttattca
     3661 ctattatctc attgccttgt ctatatacaa gtccatttac atcatttatt tccatctttc
     3721 cttgcaagtg aagtactaaa tctctaaaaa ttaattctcc ctctccataa agtatataat
     3781 ccacaaaatc atactttttc attgcctcat aactatcata actcacttcc ggtccgccca
     3841 aagctatttt agtattaggt ctaatttttt ttagattatc acaaagttta actatatctc
     3901 ccacattcca gatatatgtt gagaataata ttatatcata ttcattttta tatatatcct
     3961 ttaaaatata gtccaaatcg ttgtttatcg tgtattcttt catattaact tctatcaaat
     4021 ctcttacaaa ttcttttaga tatcttatag ccaaatttgt atgaataaac ttggaattta
     4081 atgttgttaa taaaattttc aaatatttct cacctctttt taagattata ctgtcttttt
     4141 gtacccctta taggttaaaa tagtatatgt aaagtctaaa taatatctat ataattaatt
     4201 tattaatttc aagtaatgtg aggaaaggaa gttttttatg gaattaattg aaaaagtatc
     4261 tatcaactct ttatcaaaaa gagatttact acttattata aagtctcttg aatacactaa
     4321 tgaaaatact caaattagtg atttcattga ccttaggaat aatatagtaa aggaattatg
     4381 ttttttaact gacactaagg aaaaagattt tttagattat ctagaaaaaa atagcacact
     4441 ctaataacct aaaccttttt aaactttaat atataaatac ctgatttaga atttattttt
     4501 atgcttaata tattatcatt aaaggttttc gacataactg ttatttgatt aaatataggg
     4561 tctactatag tattaccttc ttcaagtctt ataagacttc ttgggtctat gcttttatta
     4621 tatgccttaa ctccaatttt atattttctc aatttaacaa catattcgga catagaaaaa
     4681 ataaaatcta tattatcttc atttaattta ctatcttcac ccaaaatgga taatatagat
     4741 ttttttatgc tattaattcc ttcattttct acagttctat cttccatata tacatcatat
     4801 agaacattta aaacatttaa taaaatactt tcttcatcat aatcttcaga tttcaaatca
     4861 atgtacttat caattaattg tattgcttta atccttgcca tctgaaattt tacaacatct
     4921 gatttgtcta attctataga aaatcctatt atcttgtctt taatactctg tagtaattcg
     4981 acatactcta ttttactatt atttataaga ttgtgcataa tggaattata cactacagaa
     5041 cctaataaat aatcaaataa aagttcttct tttttaaaat aaataacata cttttttatt
     5101 agtttaataa cctcatcttc acttttttga atattagtat ttgataaaat tagtggtaat
     5161 aaaatattta aaaaattgat atttcctatt ttttctccat aaaatctata gtaaataagt
     5221 tcatctctca gtctattttc gtctatatac acacatcttt gcgttttatc atctattaag
     5281 gattttgtat ttattatagt taaatcttta agagccctac ttgcactact aaaagaagat
     5341 gtgtagactt tttttagtaa ttcgtcattc ataaatatat cctttctgaa aaattgaatg
     5401 taaataaatt gttattaaaa aaaaagagac agcccgttta agaagctgtc atatataggg
     5461 ggatagtagt gtacaaaaat cattgtaatc tactatctat atattattat acgatactac
     5521 ttttttatat gtaaagcatc agttttcgac atccctatat tttacagtta tacaaattgc
     5581 gtactaagtt caattttatt ctttttattt caacatttta tcatgctaca ttctttcagg
     5641 agcgtgcatt cccaacaatt tcagagaatt ttctaaagtt tgttttgttg ctaaaactaa
     5701 tgcaagtctt gcttttctta tttccaaatt ttctactaaa attggattgt catgataaaa
     5761 tttattaaac gcttgagcta aatctagcat aaatctagtc actatatgtg gctcattttt
     5821 ctttagagca agtaaaatat tcttattgaa tgattctata actctaagaa cttctgcact
     5881 atcttcatca gctaatagac tataatctat atcagaagtc acttctactt ctgcttttct
     5941 taaaactgca cagcatctag catgtgtata ctgaacatat ggtccagtct caccatcaaa
     6001 actaagcgtt ctttcccaag agaaggtata gtctttaatt ctactattag ataactcttg
     6061 gaatactact gccccaacac ctacttgctt agatatttca tccacatttt tagcatttgg
     6121 gtttttagct agtataattt ccttagtttt atctatagct tgatttaaag catcttctaa
     6181 aaatactact cttccttttc tagtcgacat agtaccttct tcaagtgcaa ccataccaaa
     6241 tccaacatga attaaatctt ttgcccaatc atatcccata agctcaatta ccttaaacca
     6301 ttgttggaaa tgtaagtttt gttgagaacc aactacatat atacacttgt caaaatcata
     6361 agtttctttt ctatatattg cagcagctaa atctcttgtc atatataacg ttgaaccatc
     6421 attcttagta ataagtgctg gtggcatttt atactcttct aaatcaacaa ttcttgctcc
     6481 tttagactct tttaaaagat ttttctcttc taatagttca ataactctgt tcattttatc
     6541 agaataaaaa ctctctcctg ctaaagaatc aaattctata tctaaaagtt tatacactct
     6601 gttaaactct tttaaactct catttctaaa ccattgccat aattcttgtg cttcttcgtc
     6661 accattttct aatttattaa accatgctct tgcttcatct tccatttctg ggtgttgttc
     6721 agcttcatca tggaatctta cgtataattt tagtaattct ggaattggat tagactctac
     6781 tacttctttt tctccccact ttttaaaggc cactattaac ttaccaaact gagttccata
     6841 gtcacctaaa tgatttattc ttatagtctt gtatccttgc gaatcatata tcttatataa
     6901 agcattacct ataactgtag ttcttatgtg ccctatatgg aaaggttttg ctatatttgg
     6961 agaagaatat tcaactatta cagttttatc ttttccaaaa tcactatgtc cgtaattttc
     7021 tttttcatct aaaacttttt taattacagt ttctgctaat tgagatttat ttacaaagaa
     7081 atttacatat ccgcctaatt gtattacttt tgttatctct ccacttggtt ctatactttc
     7141 cgccaattca cttgctatca tgtttggagc ttttctaaac actttggcta atttaaagca
     7201 tggaaaagca tagtccccca tatccttatt tggtggaact tctataagtg cctctatctc
     7261 ttctttcgat aaatcttcta ttttttcttt aaggcaattt gatattgcca ccttaaaatc
     7321 ttgcattctg ttgctcctct ctacattgtt cctggtttat attgtgctta tctctttatg
     7381 ttaaatcaaa tttcgtgttt tttcaagtat ttcattacag tgtaaaacac tttagtaatt
     7441 atgttttctg tatatattaa aaatactata attgcagttt ttaatcacac tattattgat
     7501 tttttataag acttttttct attttattgt ttcttgtact atccagttga ctttatatac
     7561 tttttttaat cttttatcta ttttcatacg tcaatgctaa ttttatatac ttttctttta
     7621 atcttttatt aattttcata catcaatgtt aactttatat acgttttttt aatcttttat
     7681 ctattttcat acatcaatgt cagctttata tacttttttt actcttttat ctattttcta
     7741 taaatctttt tcactcttaa cttttattcc ttcttcttct aatagccttg ctgttatacc
     7801 tttccctggt atctttttac ctgaaaaact accatcatat attagattac atccacaaga
     7861 ggggctaccc tcttttagta ttgcttcgct acatacatat aaatttgcta tttttagagt
     7921 ttcattagcc cctcttacaa agttttctgt tacatcctta ttatctttag taattacttt
     7981 tccatcaact atctcagcag gtggtcttgg tgtagataga ccacctaact gctctgggca
     8041 tacaagtgta aattctttgc cttttaaata ttccttgact ttttcattat cattattatc
     8101 gccactatat ttacaattta ttcctattaa acatgcagat accaatatca taaaaatgtg
     8161 ctcctataca aattatatat attctcatac aaattactaa tgtattctta tacaaattat
     8221 tttaatttaa caattgttac tcctgctcca ccttctccat attgaccacc tctttgtgat
     8281 tttacatgtc tatttcttct taaaatgtct tgtagccctg cttttaatac tcctgtacct
     8341 attccatgta ttactgttac agactctaaa cctgccacat atgcatcatc aagatacttt
     8401 tctacttcca ttatagcttc ttctaggttt aaccctctaa ggtcaacttc attttttaca
     8461 ctaccagatt ttgaccttat aatgtttctc gttgatttag ttacatttgt tgaaacatct
     8521 ttgcgtgttt tttgtaaaga tttaaaaggt agagtcatct tcattatacc aatttgcact
     8581 actgcttctt ttctcttttt atctactgaa actacactac cattttgatt taaagttatt
     8641 accttaactt cttcacctgg ctttaagtct tttatctcct tatttgatac ctttggaact
     8701 atcatacttt ttactgttgg ctgaagactt cccatagagc tagtcaattc ttttctaagt
     8761 tcttctatct tacgattctt ttcttttgaa gctctttctt gttcaagact tctaagttct
     8821 tttattataa tatctacttc ttctttagct tgtcttataa ttgaaaatgc ttctgattta
     8881 gctttttcaa tcatcttatc tctttgactg accaattttt caagtttttc gtcatactct
     8941 actttcagtt tttcaatctc ttcttttaat ctttcagctt cttctctatc ttctactgct
     9001 ttgattctat tcttttcaac attctgtaac acatcttcta aagctatgtt ttctgtattt
     9061 atatattctt tagcacgtga aatcacataa tcacttagcc caagttttct agaaatctca
     9121 aacgcatttg attttccggg aacacctata agtaacttat atgttgggct taaagtttct
     9181 atatcaaatt caactgctgc attttctaca cctgatttag taagagcata atttttaagc
     9241 tcactatagt gagtggtagc tatacattta gctcctacag aatttatatc ttctaatact
     9301 gctattgcaa gggcagctcc ttcaacaggg tctgttcccg ctcctaactc gtcaaatata
     9361 actaaagagt ctgctgttac gttttgtaat atagatacta tattcgtcat atgagatgaa
     9421 aatgttgata gactctgttc aatactctgc tcatctccta tatctgcaaa tacattatca
     9481 tatacacaca tactacttcc ataatcagca ggtatatgaa gtccactttg tgtcataagt
     9541 gcaaatagac ctacagtttt tattgtaaca gtcttaccac ctgtgtttgg acctgttatc
     9601 accaatgtat ggaagtctct tcctaaataa attgtatttg ctactacctt ctttttatcc
     9661 aacagtggat gtcttccatt ttttatgttt aaatatttat cctcatttaa agttggttct
     9721 attcctctca tctgtataga aagttttccc tttgaaaatg caaagtccaa tcttccaagt
     9781 atctcttgat tagagattaa atcttcgctc acttctccaa ccatagcaga aagctctgat
     9841 aaaattcttt ctatttcctc ttgctctcct agtttcaact gcctcaattc attgttcatc
     9901 tctactatag tcattggctc tataaaaagt gtcgcaccag aagatgactg gtcatgcact
     9961 ataccagcta cttgcgacct atattcagat tttacaggta ctacaaatct atcacctctt
    10021 agagaaatta ttgcatcttg taagtacttt tgataagtag ttgaacttat tattgaattt
    10081 aattttgacc taatggattg atttttttgg gctattcttc ttctgatatc tctaagtgta
    10141 tttgaagcat tgtcagatat ttctacttca ctaattatag cattgtatat ctggtcttct
    10201 atgtccttgt atacatacag agaatttgat agagattgta ttattggata attaaaatct
    10261 tcttcatcac tactagataa gctatttctt aatcttctag ccactcttaa ggtatctgct
    10321 atcataatca gacttcctgg atcaagagaa gcacctatat aagctctctt taccttatct
    10381 tctatatcat gaataccttc caaccctact gaacctctct ttataataat tgattgagct
    10441 tcactagttt cttctagcat agatttcact tctacaaaat cagtatttgg tactaaattt
    10501 tctatatatt ttagacctaa agaagatgag gctttcttct ttaacaaatc tattatttta
    10561 ttgtattcta gaactcttaa cgatttctca ttcattttct atattcacca tcctcgatat
    10621 tttaactttt ttatttaatt ttaaaaatgt atgttttcaa gcatttccaa taaaaactgc
    10681 aagttttatt tctttttcat ttctaaaatt attatatttt ttctctttta gatatatttt
    10741 acacatattt tgtattatac tatgtatgta gctatctata tattatacat aaacatgctt
    10801 tatttgtaat ataatctgtt aaaaaatctt ctttaatatt tttaaaggag tttattttag
    10861 cttataaaaa aaaatagcta cttatataga taaattaagg aggaacatga gtcatgggaa
    10921 acgtattaga aggattaaaa ccagaaagtg tttttaaaaa ctttgagaaa atatctcaaa
    10981 ttcctagagg ttctggaaat gaaaaaggca taagtgattt tttacttagc tttggtaaaa
    11041 atttaggtct tgaaactatt caggatgaaa gcttaaacat aataataaga aagcctgcta
    11101 caaaaggata tgaaaattgt ccaggtgtag ttcttcaagg acatatggat atggtttgcg
    11161 aaaaagaaaa gaatgttgaa catgattttc ttaaagaccc tataaaatta agaattgatg
    11221 gtgacatgat atatgctact ggaactactc taggagctga caatggtata gctgttgcta
    11281 tgggtatggc tatattagaa gataatactt tagagcatcc tgcactagaa gttttagtta
    11341 ctgttaatga agaagatggt atgaatggtg cagatgcact agaccctagc ttaattaaag
    11401 gtcaatatat cctaaatatg gactccgagg aggaaggata cttattagtt agctgtgctg
    11461 gtggtaaaac ttgtgttgtt agtttacctg ttgaatacaa ggaagttaaa ggtgacaaac
    11521 aaggattatt agttgaggtt actggactat taggtggaca ctctggtatg gaaattgttt
    11581 tacaaagagc aaatgctaac aaagcaatag ctagagtatt aagtgtgttg aatgttgatt
    11641 atgaattagc ttctgttgat ggtggtacta agcacaatgc tatacctcgt gaagctaaat
    11701 gtgtaatagc tgttaataaa gctgatgttg aatctgctaa aaaacaaata aatgacattt
    11761 taactgcatt taaacatgag tttactactt ctgaccctgg catgacttac tcagtagctg
    11821 aaacttctgt agacaaagtt cttactaaag attgtaaaga aaaagttgtt caaatgtctt
    11881 gcttaactcc tcatggagtt caatcagtaa gtcttgatat agaaggatta gttgaaagtt
    11941 ctactaactt cgctataatt gaaactaaag aatctactat tgaattttta acttctgtta
    12001 gaagttctgt tatgtctatt agagatgaaa ttgctgatag aataagactt ttggctcaag
    12061 ctttaggtgc taattacgac cttatagctc aatacccagc ttgggaattt aaaaaaggct
    12121 caaaattaga aaaaatatgc agtgaaactt atgagaaatt aactggtaaa gttcctactg
    12181 ttatggctct acatgctggt cttgagtgtg gattattact tgataaactt cctcatgctg
    12241 aagctatctc tataggacca gatatgtttg atgttcatac tccaaatgaa catgttagta
    12301 tcccttctgt agctaatgtt tgggattatg ttattgaaat attaaaatct atgaaccaat
    12361 attaaatttg agttttgatt ctaagtagat tttaatttta agtaatctat ataaaattaa
    12421 ctctgtaaat taatactact gttagtataa tatttacttt caatattaac ttatagaaat
    12481 aaagcctaat gatagataat aacatgtatc attaggcttt attgtaattt aaatattatt
    12541 aagctttatt ctgttttaaa attaattctt atactatttt aaatctattt cttccttgtc
    12601 tcttagaatc ataaagagca ttatctgcta tttgatacag ttcatcatac tcttgaccag
    12661 gctttgctat aactaccccc atactaatag ataaactttc tccatttggc aacttaatga
    12721 gatgaatatg attgtataca tcattacatt tattaataag ttcttcctta tttattatat
    12781 cattgatata aacactaaat tcatctccac ccaaacgacc tactatatca ttttttgcaa
    12841 aactttcatc aagtaccttt gcaacatcaa taagtacttt atctcctaac aagtgaccat
    12901 aagtatcatt aatcgattta aaataatcaa tatctataat caataaagca ccattttttt
    12961 cagttgataa attcaacaaa ttttgtgaag ttaattttct aatatatgct gcattataaa
    13021 tattggttaa actatccctt tgagccttat ctaacaatct attcttttcc tctttttcag
    13081 aatcaatatt acatattttc ccgattacat acattggtat ttttctatca ttataaatta
    13141 tttttgaagt aactctaatc caatgaaaag tatcatcaag cataatagaa tacatttcag
    13201 ttgttccatt ttcttgtgat tttattacat caaaaaactt tttattatat tctttcctta
    13261 ttttatctct ttcattttct atattgccat tttcactttc cttatcattt ttatccaaac
    13321 cataataagt ctcaataccc ttttctggca tagaaattat caatttatct tgcttataat
    13381 catactcaaa aaagtattca cttgtcattt catacaactg agtatgtttt ttgagttcta
    13441 aagatatctt ctcgttcata cttgtacgag tatgtaaacc aaatgccata aatccaataa
    13501 tacaaattaa taaactggct acaataaaaa tagtctcaat tggattctgt tgcataatat
    13561 aaagcaacga gaaatcttgt ctatatgtag tattttggta gacaattgat tgcatttttt
    13621 ctgatgaaat acttataata gctttattaa atatattcaa taattcttgt ttatcttttt
    13681 taattatacc aaaacaaata ctctttgctt tataagtttg aggaactaga cgcacatttt
    13741 tatacttagg ttgattcata tagtactgca tagaataacc ttcgccataa gtgtaatctg
    13801 catagccttt attaacagct tctatacact cttctaaatt atcataccaa actatattct
    13861 cttcaaactg accataataa ttaatacctt tggctagagc tacacgtttt ccatctaaac
    13921 tattctcatt taatttatta ttaatcatca tagtatattg agtagaaaga aaaggccgag
    13981 acatagctat attatgttca cgagagtatt cataatcata aatcattcct gctacaatat
    14041 caatttcacg ctttttagtc atgttttcta aatcttcttg agattttaca ggcacaagtt
    14101 caaattctaa gcctgtttta tcacatatat gatttaacaa atcaattgat atacctctta
    14161 attcacctgt atctttatct atattttgaa atggtggttt gtttaaaagt actcctactt
    14221 ttaatttttc tgtctcttta atgtaattag tttcttcatc agataaaaac atttgattat
    14281 tctctggtgt aaagtatttt tcatataaag tagttgaaaa atatgggtct ttctgttcaa
    14341 tattattaat tgctgagtta agcttttgag ttaaatttgt actaccttta ggagtaatga
    14401 aataaaatgg ttttgatgaa aattttgcta cagtacgtac accttctatt gggttcatac
    14461 tcacattaag aagtacatct gctttaccac tctttagtgc ttctagttgc tcatcatttg
    14521 ttttacaata taccaattca ggtgacataa gattcatttt acaatactca tctaattctt
    14581 taagtctagt atcagaattt tctattacag caatacggat ttttttcaca tcttgtgaac
    14641 tcattatgtt atcaatatct gtattttcat ataatgcttg tagtactgta tttgctactc
    14701 cataattatt ccctgcataa ttatatattt tttgcattgg ttcattgtat aacatacctc
    14761 ccattatatc aatttcacca ttttctaaca tcttcattaa ttttgtaata gattcattta
    14821 tctctccagg aacttgaaca aattcataat tccatccagt atactgtgca atttctagta
    14881 aatattcata tgtataccca aaatagttac cttgctcatc tatttcagtt aaaccttttt
    14941 gaataggata agcaacacga atggtacgat tatcattacc tatagcgttg ataccaaaag
    15001 aaaatatgca agaagtgaat atagatgtaa ttacaataat taataaaagt aattttttta
    15061 aattcactac acaatcctcc atatagttaa gatttacagt ataaattact gcataaactt
    15121 gtagacatgt aaaaatagat tagtatataa aaggatatat aaatctactt agaaatttaa
    15181 atatccttaa tatatacaat atatttaaat tataactcat ttatatgtct attacaacaa
    15241 atttaccctg ctaaatacct actctatatc ccataatttt acaagttgta gtgaagttta
    15301 agttctatct cacctcaaat ttagcagtgt ttctatttac agttctttta tatttcacat
    15361 ctggataacc caatataaat gaagtgataa cagcttcgtt ctcgctcatt cctaacagtt
    15421 cttttatctt tggctctaca tttgatgcca taacaaaaaa tccattataa caaattccta
    15481 atccttgaga ataggccata agttccatat tagatgcagc caatcctcca tctacataag
    15541 cacttccacc tagagacata tcacctacaa ctaccataag tagtggggca tcataaaata
    15601 aagaatcatt tccgttctct ttgtatcttt tgtacatttt cttaaatgta tttttataca
    15661 tagaacgtac agggtcattg tcatcagtat ctaatgccaa attataaaga ccttgtattg
    15721 ccagttcttt cacttctttt agcttttctt ttactaatat gtatcttata ggctgtctat
    15781 taccacctgt tggtgtgtat ctaccagctt ccactatgtt ttttattttt tcttcttcta
    15841 cctctatatc tttatattgt cttatacttc ttctaaattt aataaaattc aataactttt
    15901 cgggttctaa ttcaaaactt tcacgattgt attctattac ttcattttta tcaaatcctt
    15961 gcatttctat tgcatctgtt gggcaaattg ccatacagtg accacagtta atacagagaa
    16021 tatttttaac ctttgcttta tcatccttaa cttttattgc atttacaaga cagtctgatt
    16081 cacacatacc acagcctaca catttttcta aatttatgtc tatcattcca aattattcct
    16141 ccttttaaaa aatttacttt agtataaaac aaatagttgt ctaagtcaat ttttattttt
    16201 ttaacaatat actagcctta actacacttt aatggagaaa aatatacata aattggaact
    16261 taaattagaa cttattcaaa gtaaaagata aaagaagtag atgtctaaaa gtgaactttt
    16321 tagttaatta gatattcttt attgtatgaa atcaagtgga tatttatcat ttcaacaata
    16381 aaaaaggctt acctctattt tggatatgtc cctgtcaagt agacagacta aaaaaaggct
    16441 atctttatgc actgagatag ccccttttcc caactactat tgtttatttt aatattatat
    16501 caataaattt aatttgctat aacctgtaag ttacatttta atttgatgta actttaaatt
    16561 acatttttaa gtagtatctt taaattatat tcttaaaata tatcattaaa ctacatttta
    16621 attaatctaa aaactatatc ttaattaatc taagaaactt acattataat cttttagttt
    16681 cccattatca tatacaatct ttgcactaaa gatatttcca gtcttagccc aatttaagaa
    16741 cagcctgtca ccttcccaca tatttaaatc gaatatttta tcattatcaa cccaaattaa
    16801 atttccttct ttacaatcat ttaaatcttt ttcagataat tcaccttcaa actcatctga
    16861 gaaatacaaa aacatatacc aatcttcttc atctttaaat tttggaaaag ttatcaaccc
    16921 tttatatgac aatgatttaa gagtaagacc agtctcttct tttacttctc taattacaca
    16981 ttcttctgga gtctctcctt gctcaaactt tcctccaact cctacatact taccttcatg
    17041 tatatcatct ttctttttat ttctgtacag catcaaagtc ttgtcatctt tttctatata
    17101 acaaatagtt gtaagtttca tgtatctcgc cttgctttct cttttatatt ctcaactaat
    17161 tattttcagc actttcaagc acatcactta tattcttcat tgcattaaga gaaagctctg
    17221 caaattcatc aaatggaatc cctatatctt ctatacttct cattgcatct ctatttacat
    17281 ttgaagcaaa tctcgtttct ttcattcttt taataacaga cttagtcttt acactggtaa
    17341 gttttttatc tggataaact aaagctatag cagttataaa cccagttata gggtctgctg
    17401 catatattgc tttttccatt aggctagttc ttgtaactcc cattccatca tgatgaccaa
    17461 gtattgctct atacatttct tcgtcaccga agttttcttt tttaagcagt tctactgttg
    17521 ttgtagcatg tccttcacat atttctcctg gctttcttcc aactatatct gaatccaaat
    17581 catgtaaaag acctgccact gcccactctt cttctttttc tggctctagt cttttggcta
    17641 attctctcat aacagcttca acagcataac aatgttttct cattctatca gtttctaaat
    17701 acttaaataa aatttctaaa gcttcttctc tcattttcac caatccccct gttttttcac
    17761 atatatgata tttttatata ttaatacaca taaattcaag tttttatata tattcatgta
    17821 tatttttcat gttatatcta ttctacacct ttatagtagt gtcctgcaac tgttccaatt
    17881 tcatctaatt tcttatacaa gtctgtagcc ttttttccaa gtttataatt attactcaat
    17941 acctcaatgt gagcttcaat aaccttttta accatctcac tatcttcaac tgtaaaatct
    18001 atcctaaata catctattcc aatttcctct aactcatata gattgtccaa catacaagta
    18061 accttcgaat tgtaaattgt acttctacag aatatatctt gtgttatcct ataacttgca
    18121 tccgtaaagt ctcttaaagc ataactactt tccttacatt tagcaactct cttgtccttt
    18181 ttacaatctc taacaactac tcccatagga cagtattctg taaccatcat aggagcatat
    18241 ccatatatta ctgcttcaat ttctacatct gtatatttta aagtttgttt aatttcattt
    18301 aagtttagtt cttgtgacaa acaaactgta cttgctccct cttctttgaa gtgatttata
    18361 ctttcactat tgaatgcatt taagtagcaa tctatattta agtctttttt cttaaagtat
    18421 tccatagagc cccagttacc aatttgaacc ttattaattc cttttatatt atccaatatc
    18481 tcaaattgct tgtactcttt atttctaaca atccttggtg ctgaatagat taattttttg
    18541 tcagtgactg ctgtattata gtggttctta ttcaaagtat ctattttact tgtatttgac
    18601 aaagtatcta tgttatttgt atttgaaccc attagttctt taggagtacc taaagacgaa
    18661 gaagtatcta aatccataga aatacttgaa tctatagaaa tatttgaatc tatagaaata
    18721 cttgagacca tttgtaaagc ttttgataat gtatttatat cttcataata gattaaatct
    18781 acattataat ttaatactgc ttctaattgc tccaagttct taactttaac tctaatctta
    18841 ggagctgtat caagtttttt ctgtttattt actctatttg gctggtattt taatctattc
    18901 ttcttaaatt ttctatcttt tatctttatt ctttcttcat ctaaaagctc aatacaatcc
    18961 cttctcatct gatttaacac acttataggc atacttacac cttcatccag gtcaatttct
    19021 atctctttta acttatatgg tgtatttcca agcttttgaa tttgtgtttc tattttttct
    19081 ttacttaaag ccacctttat agctttttca actattttgt ctccttctac caccgattta
    19141 tttccacaaa aatcacttat aaaaagctct ggctttttac ctagtttaat actcactttt
    19201 gcacgtatat tagtttttat gaactcttta tcttgctgaa atgtagcttg tactctatcc
    19261 attaattcgc tgtcagaagt cttatatata agctgatttc tctttgcttc tccaacaaaa
    19321 tctaattcta tcaaatcccc tttatgtgct attgtagtta tctctccatc ctttattatt
    19381 cttccaatag tacctccacc taagttaatt ccatcacctt tcttaagcgt attttctagc
    19441 attactctaa gtcttttgtt ctttctatta taatctaaaa cttttccaat atatagccct
    19501 tgattattag gtctattaga gttcattata tccttaccaa cttcacctaa tatatatcct
    19561 tttgtaaact ttctattaaa tatggtatac aaattattta ttatttcctc agaaatactt
    19621 atttttttct tatctacaaa ttcattaatc gcttctctat atcctgaaac cacagtagct
    19681 acatactctg gctttttcat tctaccttca atttttaaag ataatacacc tgcttcaatt
    19741 attttatcca aatcttctat agtacttaaa tctctaggac tcaacaaata atctccatta
    19801 ctttttacta cttctcctgt atttatatct atcaactcat acttttgtct acatggctgt
    19861 gcacacctac ctctatttcc cgacctattg cctatcatac tactcataag gcattgaccc
    19921 gagtaacata cacataaagc tccatgtaca aaaacttcta tatctacagt tgtattttca
    19981 caaatccatt ttatctcatc aacatttaat tctcttgcta aaacaactct atcaaaccct
    20041 acactctgaa ggtattttac atcttctaag gaatgtgcta ccatttgagt gcttgcatgt
    20101 agttcaaagt caggtaatag tttttttata agtcttgcca ttcctatatc ctgtactatt
    20161 aaagcatcaa tatctatatc gtataaaaat tttacatact ctacaaaatc ttctatttca
    20221 tactgtttta tcaatgtatt tacagtaaca aagacttgca ctccccttat atgagagtat
    20281 ttaacagcct caatcagctc atttctatca aagttatttg cagatgctct agcactaaag
    20341 tctttaccac ctaaatacac agcatttgct ccgttttgaa ctgctgcttt taatgaatca
    20401 aaagagccta ctggtgcaag taattctatt tttttcatat ttttctcctc tatttatact
    20461 tgttaggtta atataattat atctataact taaatatttg tattaaattt atatatttct
    20521 tac
//
LOCUS       DAEPXW010000071        20469 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.072, whole genome shotgun sequence.
ACCESSION   DAEPXW010000071 DAEPXW010000000
VERSION     DAEPXW010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20469
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.072"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            64..288
                     /locus_tag="KRM55_002567"
     CDS             64..288
                     /locus_tag="KRM55_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594790.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            341..865
                     /locus_tag="KRM55_002568"
     CDS             341..865
                     /locus_tag="KRM55_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1594791.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EVMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(970..1116)
                     /locus_tag="KRM55_002569"
     CDS             complement(970..1116)
                     /locus_tag="KRM55_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594792.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(1255..2181)
                     /locus_tag="KRM55_002570"
     CDS             complement(1255..2181)
                     /locus_tag="KRM55_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH1594793.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            2371..4242
                     /locus_tag="KRM55_002571"
     CDS             2371..4242
                     /locus_tag="KRM55_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBH1594794.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYVSLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            complement(4334..5269)
                     /locus_tag="KRM55_002572"
     CDS             complement(4334..5269)
                     /locus_tag="KRM55_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBH1594795.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            5789..6301
                     /locus_tag="KRM55_002573"
     CDS             5789..6301
                     /locus_tag="KRM55_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBH1594796.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            complement(6456..7517)
                     /locus_tag="KRM55_002574"
     CDS             complement(6456..7517)
                     /locus_tag="KRM55_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBH1594797.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(7641..8534)
                     /locus_tag="KRM55_002575"
     CDS             complement(7641..8534)
                     /locus_tag="KRM55_002575"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBH1594798.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            complement(8544..10025)
                     /locus_tag="KRM55_002576"
     CDS             complement(8544..10025)
                     /locus_tag="KRM55_002576"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBH1594799.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYIKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     misc_binding    complement(10133..10364)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            11166..12074
                     /gene="trxB"
                     /locus_tag="KRM55_002577"
     CDS             11166..12074
                     /gene="trxB"
                     /locus_tag="KRM55_002577"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH1594800.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(12164..13987)
                     /gene="typA"
                     /locus_tag="KRM55_002578"
     CDS             complement(12164..13987)
                     /gene="typA"
                     /locus_tag="KRM55_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBH1594801.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            14199..14441
                     /locus_tag="KRM55_002579"
     CDS             14199..14441
                     /locus_tag="KRM55_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594802.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            14589..14780
                     /locus_tag="KRM55_002580"
     CDS             14589..14780
                     /locus_tag="KRM55_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBH1594803.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            15064..17565
                     /locus_tag="KRM55_002581"
     CDS             15064..17565
                     /locus_tag="KRM55_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBH1594804.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            17725..18393
                     /locus_tag="KRM55_002582"
     CDS             17725..18393
                     /locus_tag="KRM55_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594805.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            18377..19654
                     /locus_tag="KRM55_002583"
     CDS             18377..19654
                     /locus_tag="KRM55_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH1594806.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            20055..20276
                     /locus_tag="KRM55_002584"
     CDS             20055..20276
                     /locus_tag="KRM55_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594807.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
BASE COUNT         7936 a         2473 c         3175 g         6885 t
ORIGIN      
        1 taagcagtat atatacaact aataataaga aaaatatcaa ttatataagg agtagataaa
       61 aatatgataa taaaacttac taaagacaat tttaatttta gatttaaaca atatgaaggt
      121 atgttttttc atgctgaagt agttgaaggt atggaatcca ttagatataa aataactaag
      181 gataaagaag gtacagaatt aaaagaattt ggaagtacac atataaaaga taatatgata
      241 tatgtacctc aggtagaagc atacatagat ttgaacagta taaaataaag atgtaaaatt
      301 ttaattaaaa ataaagatta tgtttgaggg ggaatccaat atgagtaagc ctatagatat
      361 aacaataaga cctataagaa gagaagatgc acaagctttt aatgaaatta gaagaacata
      421 cagtgttatg agaaatactt tggcattaat gagtgacaga gtcgataaaa ctgaagttat
      481 gttagcttct ttgggagaaa atgattatat gtttgtagct gaaactaata ataatggaga
      541 aaaagatgta ataggttttg ctgggttaca tgtaaattct tctccacgat tgagacatag
      601 cgcagaaata ggaataagtg ttgcagagaa ttatcaggga agaggagtag gtaagaagct
      661 tatggaacaa cttttagata tagcagataa ttggattatg ttaactagag taggattaga
      721 agtaattgtg gataatgaaa agggattaaa tttatataaa aagctaggtt ttgaaataga
      781 gggaactaaa aaatatgctg taatcagaga tggaaaattt gaagatgttt atattatggg
      841 aagatataat aaaaatttaa tttaaataag ctaatagaga agtaaaatag agtgtcttta
      901 ataaaaaatt tacattaaag ataatctatt ttacttctct attgtgttaa aaaacttatt
      961 tttaaatgtt tacaaaaaca ttctatatac aaataaaatt attagcaata tcaacgctat
     1021 tttaaaagct aaactagcaa cagttttaat gatttttaca gaaacaccta tagcaactat
     1081 agcaaatact attttaaaga gtaaatccat atccatattt aagcctccta ttctataata
     1141 catatagata ttattgacaa atatctagga aaaaattcca tcaatatact acaataaaat
     1201 gtttatattt gtaatttatt gaatatgtta ttatataata cataaaaaaa taaatcaaga
     1261 taagagtaaa atacttataa aaggtataga tataactgaa aatagtgttg taaaaaacac
     1321 acattgtgaa gctagtgtta tattggagtc atattgatta gccattatag cagtatttgc
     1381 agcagcaggc attgaagaaa ttactactgg tatagctaaa atcatcttat catttatcca
     1441 tccttttaga ataaaataca caatcacagg aagtaccaat aatcttataa aagtgactat
     1501 atataatttt ttgttgacaa aacaatcgag agctgaagaa ttagcaagta agcttccaat
     1561 gataatcatg gatattggtg tagttatact tcccaacatc tcaagtggct cgtttataaa
     1621 ttggggtaac ctaagtcctg ttacaaataa aaaaagtcca ataacaatag ctattgtagc
     1681 agggcttata agtgatttta ttgaaaaacc tctacttgta ctgcctttag ataaaagata
     1741 aattcctaaa gtgaaagaaa ataagttaaa aggcaaattg aatattgcag tatagaatat
     1801 tgcttcatga cctaaaactg cttcaattac aggataaccc ataaaagcaa catttgaaaa
     1861 aacaactata tactggtata ttcccaaatc ttttttatca ttacatttta aaatgtattt
     1921 caataaaaat gcaattataa ttgaaactat atacataatc aaagatgtaa ataataacaa
     1981 tagtattttt tgtatcattt tactatcaaa gttaatttgc atggagctaa ttatcattga
     2041 tggtaaaaaa actgtcattg tcaaagttga aagcttagat gtgcagtggt catctaataa
     2101 gttgaatttt ctgacaaaat atccaactaa aataattata aataaaactg caacttggat
     2161 aaaaatattg ctgaaattca taaaatgtcc cccctatata tacattatat accaattaca
     2221 taataaaatc taatgattat aaaatttaaa atttaatgtt acaatatagt gacaaaaggt
     2281 aaaaattcaa tattatagca ttaattgtag attataatgt ataataatgt ttgagagaat
     2341 atattttata aaatgggtag gtagcgaata atgaaaaata caaaattttc tataaaaaaa
     2401 ataaaaaata tatctaatga cccgaaagtc gtacatacta agggtgccct ccttgaaaag
     2461 atgggtaaga tggaaagcgc aatagagttg tataagagtg ctgcattgga taattacgta
     2521 aaatctcaat atactttagg aaatatatat gaaagtaaaa aacaatttaa agaagcagaa
     2581 aagtggtatt caatggcata taaaagtgga agtgaagatg ctgcttttga tttaggtaat
     2641 atgtactata agttagatgg ctatgaatat gctatatatt ggtatgaaaa gatagcaaat
     2701 ttaggttatt tacaagcaca aaataattta ggtgtatgcc attttaaaat gaaagatttt
     2761 gtaaggtgtg aaaaatggtt aaaaacagca gcagacaaga atttaggtaa agcttgtttt
     2821 aatttagggg tattatatac ttttttggag aaagatgatg aagcatatga atactataaa
     2881 aaaggttctg tgcttttaga tgatgatgca aaatataatt tagcaatatt aaatggaaaa
     2941 aagaaagata ataaatcaac agtaagttta tataaacagt tgtacaagtc aggtcatatg
     3001 aaaggttgct ttaacttggg tatgattatg gaaataaatg ataatttaga agatgcagag
     3061 aagtattata aaaagagtgc tgatagagat gatgtgaagt ctgagtatag gcttgcatat
     3121 gtatatgata gaaaagaaga gctgggagat gcaatttatt attatgagaa agcaatagaa
     3181 aaaaatcata cactttctaa gtatagactt gctaatttat ataatagaga aaatgagata
     3241 gagaaggcaa aaacttatta taaaatggct gctgaagatg atataacaga agcaaaaaat
     3301 aatctggcag gtatatattt tgaagaaaaa gattatgaaa atgctattaa atattatgag
     3361 gatgctatag ctgttggatg caaaagttcc cttgaaaatc taggggattt atattatcag
     3421 aatcaagata tagaaaaagc gatttcgtat tattcgagga ttccaaataa tgtatcttgt
     3481 caaatcaaat taggaaatat ctatgaagat ttaaataata ttgaagaagc aataagttgg
     3541 tataagaaag catctgaaaa tggagatacg aggtctagtt atagattggg gtgtatatat
     3601 gagagcttag gaaatacaaa aaatgctaga aagtattttg aaatggcaag tagcaaaaac
     3661 catatgaatg ctcgtataca tctaggtaga atttatttta gagaaggtaa attggaagag
     3721 tctaaaatga tgtttgatac acctgccaat gaaaataatg tgtatgctca acatatggta
     3781 ggattaattt atgatatgtt ctataaagat tatgtaaatt ctaaattttg gtatgaaaag
     3841 gctagagcac aaggttgtgt tgaatcaata tataatttag gtcaaattta tttaaaatta
     3901 aatgatgacg cagaagctga gaaatattat aaagaaggta ttaaatatgg aagtaagaag
     3961 tgtgagtata tgcttgcagg tctttattat aaaaagagcc tagatatgta cgtttcttta
     4021 gcaaatgaag agtacgataa ttgtgaagag atagtagaag gctttcctaa tttaaatata
     4081 gactttgatg aagtattaat tcctccattt aagttgcaag aagaggtaat agatgaagaa
     4141 gagtatgtac caatttatat actaaatata aaagaaagtt tagattcaat gctagaaggg
     4201 cttgaaactg aaatgattat agatgaagaa catgatagtt aaaaagtatt ataagattat
     4261 atagatttaa atatataaaa gccattagga taaatgtaaa tcaattaatt ctaatggctt
     4321 ttttattaat attttataat agcttatttc ttgacatgaa aaatgtaatc actatacata
     4381 ttatagaggt aataagaagt attatccaaa atccgtttgg gttattagaa aatggcatgt
     4441 tgatgacatt cataccaaag aatcctgata ttattgtagg tattgagaaa attagtgtaa
     4501 ctactgttaa aatttgcata acattattct gattattact tataattgca ctgaaagcat
     4561 ccataattct actcaatata tctccatata ttttagccat atcaagagcc tgtctatttt
     4621 caactataac atcttctaat aggtcttcat catctggata cttctttata ccagcagttc
     4681 taaccatttt gtttaaaaca agttcattag attttagtga ggtagagaag tataccaaag
     4741 atttttctaa ttccaataat tgaaccaatt ctttgttttt cattgatttg taaatttctc
     4801 gctctattat gattgtcatt ttatttattt ttcttaagta atgcaagtaa taagctgcat
     4861 ttttgtgaag aatttgaagc aaaaagcgag tctttttaaa cgtaaaaaaa tctttaatat
     4921 gaccaactat aaagtcattt aaaatcttag tttgtgcatc acaaactgtt acaatagctt
     4981 cttcagttag tataatacct aagggtattg tagtataatg agaagaatta gagtcacttt
     5041 cgtctactgg tatatctata agtataagag tatgattgtc ttcaacatct attcttgagc
     5101 gttcttcttc atctagtgca gattctatgc tttctacatc tatatttaat aaattagaaa
     5161 tttcgttgat ttcactatga ttaggttcaa caagatttat ccaacagcca tcttcaaaaa
     5221 aactaagttt ctctaatttt gaatctatag ttttgtaata tcttatcatg gcaacacatc
     5281 ctttattcag ttttatataa atctcatcat ttaatagtat ctattaatta actaatttat
     5341 ataactgaat atatgtatta gttttgattt tagatattat taagtgatga aaatgtaaaa
     5401 aattctctcc gcaacggact agtatccatt gcccatcact ctccttattt attattttat
     5461 atatagctat ttatgaaatg cgtattttaa gcactcttta atataatacc ttttccaggt
     5521 atataaatca agttttgatt tgattaaata atatttttac cataatttac acataaagta
     5581 tataagttat atttaatttg agtaaagaat atatatattc tgagtgaaat tattaaatat
     5641 attaaaaaat aagagtgtat atatatattt acttatttgc aataatatat ttaaaaaagt
     5701 attttatttt caaaactaga cttcatttat aatttatcat gaaaataaaa ggaatataaa
     5761 tataagagaa tgagaggtta ttagagatat gagtgatttt aaagaaattt tggcagaaga
     5821 gattaaaaat aatccatttg gattgatagg taaagattgg acacttataa cagcagaaaa
     5881 tgaaggtaaa gtgaatacaa tgactgctag ctggggaggg cttggagtta tgtggggaaa
     5941 agatgttgct tttgtagtaa taagaccaca gcgttatact aaggaattta tagataatac
     6001 agataaattt tctcttacat tttttgatga agattttcgt aaagagcttt catattgtgg
     6061 aaaagtatct ggtagagaag aggataagat atcacagatt ggatttaata tagaacactt
     6121 aaatgataca ccttatttta aggaagctaa aatggctatt atatgcaaaa aaatgtatag
     6181 tcagaaactt gaaccccaat gttttattgc tgaaggtata gatggaagat ggtatccaca
     6241 aaaagattat catactttat atatagctga aataaccaat gtacttgtaa aagaagatta
     6301 gttataaggg ttaatactat ctctaattaa attaaaattt caataaaagg aaattgacac
     6361 aaaaaagcta aggacataaa tatgtttata aagattaata aataacgtat ttaaactcct
     6421 tagcttgata aaattttaat ttagttttct ttaaattata attcagaaat caattcattg
     6481 ataacatctt caacagtact taatttatca attttatagg catcatttcc acaaaataaa
     6541 agtgaatttt caacatctcc tttaactgca ttgattagag cttgagaaat acagtaagga
     6601 gtttcttttg gattacaagg aatcaaacaa ttatagcact tctttatttc tggacgattt
     6661 attttaactt cttctataaa tttgtttctt atggcacgtc caggaagacc tacaggactt
     6721 ttaactatat gaacatcttc ttcactagca tttatgtatg ccattttaaa gttctcatgg
     6781 gcatcacatt cgtaagtagc aacaaatctt gtaccaactt gtacaccact tgcacccata
     6841 tctatatatt ttttaacatc actactagaa gttataccac cagcagcaac tactggtatg
     6901 tttctaccaa atttttctcc ataagtattt gcaaccttta aaatttcaac aaattcctta
     6961 tcatagtcta tagaatctat gttatcaagt tcctcgttag agtatccaag gtgaccacca
     7021 gcttttggac cttcaacaac tattaagtca gcagtagttt tctcttttct atcccacatt
     7081 tttaaaatta cattagcagc ttttgcagtt gaaactatgg gtgctatttt tacattactt
     7141 ccctttacta atgatggtag cttattaggt aatccagctc cagatattat aaggtctaca
     7201 ccagctttaa cagcttcctt tacgtatgtt tcatattctt tcatagctac cataaaatta
     7261 ataccaataa taccaccatt tgagatttct ttggccttag aaatatgttt ttttatagct
     7321 cttaaatttg catttatagt attagtttca aaatcttcct catcatatcc aatttgaact
     7381 ccagaaatta caccaacacc accaagctta gcaactgcac cagctagtga tgacctagat
     7441 ataccaacgc ccattccacc ttgaattata ggaacttttg caactaaatc tctaattatt
     7501 aactctttta tgataatccc tcctcaatgt aaacatgttt aaagaactag attataatac
     7561 ttaatattat tacctagtcc taattattat actacaaatt ataataaaag agtagttata
     7621 ttttgtatag aagacgataa ttatattata tttaaaacag ctccattaga atcgcaacat
     7681 aactctttta tttcccaatc agattttagt ttttgtaggt aatttttcat attatccaca
     7741 aaactatcat cattttcttt tattaaagac attatagtag gtccagctcc acttaaaaat
     7801 actccaatac tatttaattg ttcagatttt tcaacaatat cattgtagtt ctcaattaga
     7861 gttcctctat aatcttgatg caatttgtct tgacaagcta ctttaagtag gtcaaagttt
     7921 ttgtttagta aggcagatat tagtaaagca actctactaa cattgaatac cccatcagaa
     7981 tatggtattt cctttggtaa aacacctcta gctttttctg ttgataactt aaaattaggt
     8041 atcattgcac aaaatttaag ttcttcagga atttttataa tatcataatg tatgttctca
     8101 ttatcagtaa cagatacaat catatttcct aaaatagcag gagcaacatt atctgggtga
     8161 ccttctattt ctgaagctat atttagtaat tgatttttat ctaaattagc acctgataga
     8221 gcatttgcag ctataactcc agctactata caagaggcac tactgccaag acctctacat
     8281 ataggtactt cactttggat ttttattttg ataccagcag gtattttttc tggtttaact
     8341 ctatcaaaaa agtacttcat agatgtataa actaagttgt tttcgttttt gtaagcatct
     8401 tcacaacctt ctatttcaag accactttca atttcttcaa cataaaattt attgtatata
     8461 tttaacgcaa ttccaagaca atcaaatcct ggacctatat tagcacttgt tgcaggaact
     8521 ataatctcta acataataat cacctatacc tttaagaatt tttttatagc tagttttaat
     8581 tcatcttttt cataaatatc tttatgtagt atttctgcat ttttaagatt tttaataggt
     8641 tttggaatat ctattttaga aatacttgat aatctatcaa ttatagcaaa gtcatcaagg
     8701 tctttaaaat cacaatctat agactttaga acatcttcag aaaacttgaa tggacttgca
     8761 gtacttacaa taacagtttt tgtgttatca gaagtttctt ttatatattt ttcataacaa
     8821 ttgtatgcaa cagcagtatg agtatctatc aaataattat aatttttaaa cacattgttt
     8881 atcgtgcttt taacttcttc ttcatttgaa tattctccat agaatgaggc taaatttttt
     8941 tccatatcat cacttatttt gtagactcct ttatcactaa ggtctgataa aagcttattt
     9001 acaatatcag tatttctatt tgatatttca aacagtaatc gttctaaatt acttgaaatt
     9061 aatatatcca tagaaggaga agtagttaat ttcaatgttc tatttttatc atatacacca
     9121 gttttaaaga aatcataaag aacattatta tcatttgatg cacatattaa tttgtttatt
     9181 ggaagaccca tttgtttggc ataatatcca gctagaatat taccaaaatt accagttggg
     9241 acaacaaaat ttattttatc atttaaattt atctcactat tgctaaccaa tttcatatat
     9301 gaataaaaat agtatgcaac ttgtggaaga agtcttccta tattaattga atttgcagaa
     9361 gataatatat aattattatc caatagtttt tgattaaatt ctttatcaga aaaaatcttc
     9421 tttacacctg attgtgcatc atcaaaattt ccttttatac caactacata tgtatttttt
     9481 ccagtttgag ttttcatttg aagtttttgt actgggctta caccatcttc tgggaagaat
     9541 acaattatct ttattttatc tatatcttta aatccctcaa gtgcagcttt gcctgtatct
     9601 ccagatgtag cagtaagaat cacaacatct ttctctaaat tatctttctt tatagatgtt
     9661 ttaagaagat gaggcattat agtaagtgcc atatctttaa atgctaaagt tggaccgtga
     9721 tatagttcta agaaataagt atcatttact ttatttaatg gagctatact actacaatca
     9781 aacttttcat catatgcatt ttctatacaa tttttaattt catcttcagt aaaatcacat
     9841 aaaaatttac taagtacaaa aaatgctatc tgagaatacg ttaaatttac taaatttata
     9901 agttcatttt ttacattggg aaattcactt ggaacataaa gaccaccatc acttgatatt
     9961 ccttttatta ttgcttgtga tgcagttact ttttcttcgg tgcctctcgt acttgaataa
    10021 tacatttttt ataatcctcc atatatttta aatttttaat tagctaatta aattagatac
    10081 agaatatttt aaaaactgaa tttaggtaat aaaaaaagac cctcatccct aaaaaaggga
    10141 cgagaatctg tttcccgcgg ttccacccaa attgatttta aaaaatccac ttgatacttt
    10201 aacgcaagta ataaaaacgt ctattcctac taaaatcatt aagataactt cggatagaag
    10261 ctcctaggta gttttcaatc cttctaatta gggaaacatt tcagctagta gtttccttct
    10321 ctggtaatcg attcagattt actcttccta atcaatgcct ttcaatattc ttaatattat
    10381 taattattct agtttataaa acagacaaag tcaagtatta atataaaaat ttggaaaaaa
    10441 tattttttaa attgtaaaaa aattgtaatc aaattgagta ttagaaaaat atttttttaa
    10501 cttttttaaa agtttaaaaa cctagatttt catagtgatg aagctgtttt taatgaaagt
    10561 aatcaaaaga taactattaa atatctgtaa tattacaatt ttatactaca ctatattaca
    10621 aaaaaagttt acaaaacttt aatttgaaaa atgtaattat atggtatatc atataaatat
    10681 aagtaaatag tgctaatatt taaactatta atcataattg gttcaacaaa agtatatagt
    10741 taataatgtt taatttgaag aaattgttag tgtgaaatta catatatatt caaattaaat
    10801 tcataaatat ttcacataat aatagtatac tgtaaacaaa aggaggtatt aaatatggga
    10861 atagtactta taacagcagc attagttttg gttatgtatg gactttcaat tctatcatat
    10921 atatcagaaa gcaatatatt agaagacact gtaaatgata accaataagg ttttgaatta
    10981 tataaataag tgagaactgt aaataaaagt taatttttat ttgcagtttt tttatatata
    11041 tgtaaaataa agttaattaa taaaaaataa tgttttgttt atagtatata tggataataa
    11101 tagtaaagta taagaatgat gagaataata tataagaaat aataatataa agagaggtaa
    11161 acgttatggt agatatcatt gtaattggtg ctggaccagc aggtttaact tcagcaattt
    11221 atgctatgag agcagggtta agcgttacag tatttgaaaa aaatatttat ggaggtcaag
    11281 ttgcaagtac ctctgaggta gaaaattatc cagcagttca aaagatttct ggggtagaat
    11341 tttctaataa tatatacaat caagcagttg ctcaaggtgt tgatattcag tttgatgagg
    11401 ttgaagagat aaatttagag ggaaaagtaa aggttgtaaa aacttcttca ggtgaacata
    11461 aagcaaaggc tgttattctt gcaaatggag ttgaaagacg taaattaggt tgtgcagggg
    11521 aacaagaatt tacaggtaga ggagtatctt actgtgcaac atgtgatgga gcctttttta
    11581 aagataaaga agttgctata gtaggtggag gaaatactgc actagaagat gctttatttt
    11641 tagctaataa ttgtacaaaa gtgtatttaa ttcacagaag agatagtttt agaggtgaag
    11701 aagtgttgga gaaatctgtg aaagcaagag agaatattga gatactttac agtcatggtg
    11761 tagaaaaaat agaaggagaa aagactgtat cgaaaataga agtaaaaaac ttaaagactg
    11821 aagaaaaaag aactatagat gttagtggta tttttattgc tataggtctt aaacctaata
    11881 ataaaatgtt tgaaaatgtt cttgatttgg atgaaggtgg atatataatt tcagatgagt
    11941 cttgtacaac atcagtagaa ggtgtatatg tagcaggaga tagtagaact aagtttttac
    12001 gtcaaataat aacagcagca tcagatggag ctattgcagc cgttcaagca gctaattata
    12061 taaatgttga ataatataaa tttcaaataa aaatagccat ataaactgaa ataatttttc
    12121 agtactatat ggctattttg ttaattagag gtaaatgtac gttttattta ccttgtctag
    12181 atttgttata tcttaatcta tcatgttcat ttaagaatct ttttctaagt cttatagaat
    12241 caggtgtaat ttcaactaat tcatcatctt ctataaactc tagtgcttct tcaagagtaa
    12301 atattctagg aggagataat tttatagcat catctgaacc agaagcacgt acgttactca
    12361 ttttcttgtt tttacaagga ttgactacca tatcatcttt tctggaattc ataccaatta
    12421 tcataccttc gtaaacttct acaccagggt ctacaaacat tacagctcta tcacttaagg
    12481 cattaagaga ataccccata gtaacaccag gtccttgtgc tattaaaaca ccatttcctc
    12541 ttgaaggtat ttctccttta aattcttcaa atttttcaaa tgaacgaact aaagtacctt
    12601 ctccacgagt agcgtttata aattcacttc gatatcctaa aagaccacga gtaggtgcta
    12661 agaactctat ttttacatag tctccttcta ttgacataga ctccatcata ccttttctca
    12721 tgtttaattc atttataata gtaccagagt aaacttcagg acagtttaca acaactcttt
    12781 ctattggttc cattagtttt ccatcttctt tatgcattaa aacttcaggt ttagaaacac
    12841 caacttcata accttcacgt ctcatatttt caagtagtat agataagtga agctctccac
    12901 gtccagaaac tttgtatcca tcagtagtat caagaggttc aactttaaga ccaacattta
    12961 cttcaagttc cttttcaagt ctatctttca aatgtctagt tgtaacgaat tttccacttt
    13021 ttccaacgaa tggagagtcg tttactaaga agttcataga aagagtaggc tcttctattt
    13081 ttatcatttc cataggtagt ggactatcta aatcgcatat agtttcacct atagatatat
    13141 caggaatacc agctataaca actatttctc cactagtagc ttcatcaact tcaacttgtt
    13201 ttaaaccttc atatacagaa agttttgata cttttccttt agatacaaca gaatcttctc
    13261 tacatatagc aacttgtgta ttgtttttaa gagtaccttt gtaaattcta cctataccaa
    13321 gtctacctac ataatcatca tatgcaagag ctgatatttg gaattgtaga ggttcattat
    13381 cgtaattagg ataagcttca acgtgattta caatagtttt aaatagagga gaaaggtctt
    13441 cactatcatc atccatttca agtttagcaa taccttgttt agcaatacca tatattatag
    13501 gaaattcgca ttgctcatct gttgcattta agtctacaaa taaatcgaaa acttcattaa
    13561 ctacttcttc cgctctctgg tcttttttat caatcttgtt tataaataat attggtttta
    13621 aaccgaactc taaagatttt tgtaaaacga atctagtttg aggcattggg ccttcactag
    13681 catcaactaa tagaataact gtgtcaacag ttttcataac acgttcaact tcagaagaaa
    13741 agtcactgtg tcctggagta tcaactatgt ttattttgta atcttcatag tttattgcac
    13801 agttttttga atatatagtt atgcctcttt ctttttcaag gtcgttactg tccataacgc
    13861 agtctttaac tacttcgttc tttctaaaaa caccgctttg agaaaggaaa gcatcaacca
    13921 atgttgattt tccagcgtca acgtgggcta taactgcgat atttataatt ttatgttttt
    13981 gtgacatttt tgttgctccc ttcgattaaa ataacttatt aattatagca caatatatta
    14041 ttaggtacaa ggaggaatat attaaattgt attaatatag tttaaattgg ataaaactgt
    14101 tagttttgca tctgaaaatt attctgttta aaaaaatttt ttagacaaat aataacttta
    14161 atagataaaa agattaataa aagagtaaag gatgatatat gttggaagta accaaaataa
    14221 taattaaata ttttgcaagt gaaagtgata cttttgtaaa agaagaagtt tgtaattttg
    14281 aagaacttct taagtggtct cataaattta ttgaaggtaa aaagatagaa gatgttttgt
    14341 atataaagtc taaagaaaac tataaagtaa atgtgattaa gtctttagaa attaaggaat
    14401 tggaaatagt gagaaaacaa cagataccac cgtacatgta gtattaataa tatataaaat
    14461 taatatgtaa tactcgcaat aggatataaa tggtatatat ggtaataatt tatattaaaa
    14521 aaacttttat aaagtttata tttgggtata aaagtattaa ttagacatta attaggagga
    14581 acttaaatat gataagagta tgtccaaact gttcaaatgt ggatgtaaat aagctaaaaa
    14641 ctttggttgg agaagaaaat gtaaagactg gttgtatagg tcagtgtaga gcatttaaaa
    14701 aagaagctgt tggaataata gacaatgagc ttgaaataaa ggaaacagaa gcagagtttt
    14761 ttgaagcatg taaagaataa attttaaata aaatataata aatagagcat ctaaattgta
    14821 taagcattaa acaatttaga tgctctattt ttatatatac atttaattat gagtatactt
    14881 ttctattaaa tacaaataaa tataactaat acatttattt attaaaaaaa tattgattta
    14941 atatacctat agggggtata ataaaaatat agatttctaa ataagtaatt tatcaatatt
    15001 acatatcaaa ataaaacgtt acaaattagc tgaaaatata ttgaaagaaa ggaagatttt
    15061 attatgagtt caaataaagt ggtagaaagt tataaaatta caggtatgac atgtgcagct
    15121 tgtgcaaagg cagtagagag agtaactaag aagatggatg gagtatatga ccaaagtgta
    15181 aatatagcta ctgaaaaact taaaatagaa tatgataatt ctaaggttaa ttttgatgat
    15241 ataaagcagg ttgtagaaaa agcaggatat ggaattataa aggaagaaag taataaaaaa
    15301 attgatatga aaattgatgg aatgacatgt gcagcttgtg caaaagctgt agagagagtg
    15361 gtaaaaaaat tggatggagt agaaagtatt agtgtgaata ttgcaacaga taaagctaat
    15421 atagactatg acccatcaaa agtaaaatta tctcaaataa aagcagctat tgaaaaagct
    15481 ggatataaac caatagaaga ggtaagaaat aaggttgatg tggatgaaga taaattgaga
    15541 aaagaaagag aaatgaagtc tttatttgtt aaatttatag ttgcaatagt atttgcagta
    15601 cctctgtttt atatagcaat gggacctatg ataataaagc ctatagggcc atggcctttg
    15661 ccagaaatta taaatcctat gacaaatact tttaattatg cattaattca gttaatttta
    15721 gtaataccag taatgatagc tggttataaa ttttatataa atgggtttaa atcacttttt
    15781 tctttaagcc ctaatatgga ttctttagtt gcaataggaa cattagccgc atttttatat
    15841 agtctatata cgacactaca aatagccaat ggacaaattc aaggtatgca ccatcatcag
    15901 ttgtattatg aaagtgcagg aataataata gcacttatct tacttggtaa atatttagaa
    15961 tcaaaatcaa aaggaaaaac atcagaagca attaaaaagc ttatggggct acaacctaaa
    16021 actgcaatag tgttagttga tggtaaagaa gttgaaactc ctatagaaga agtagagata
    16081 ggagatatac tattggtaaa accaggaact aaaatacccg tggatggagt tgtaatagaa
    16141 ggatatacat cagttgatga atcaatgctt acaggtgaaa gtataccagt agaaaagaat
    16201 gttggaagta aggtgacagg agctagtatt aataaaaatg gtgttattaa gtttaaggct
    16261 gaaaaaattg gtggagatac tgctcttgcc caaataataa agttagttga agatgcacaa
    16321 ggtacaaaag cacctattgc taaacttgcc gatactgtat ctggatattt tgtaccaata
    16381 gtaattgcaa tagctgtagt tgcatcatta ttgtggtttt taataggagg aaaagatata
    16441 gtatttgtac ttactatatt tatatcagta cttgtaattg cttgtccttg tgcattagga
    16501 ttagcaacac caactgctat aatggttggg actggaaagg gcgcagaaaa tggaatcttg
    16561 ataaaaggtg gagaggcact agaatctgca cataaagtaa atacagtgat atttgataag
    16621 acaggtacta taacagaagg aaagccaaaa gtaacagata tagtattaaa taataatgta
    16681 aaagaagaat atcttatcaa gattgcttca agtgcagaaa aaggttcaga acatcctctt
    16741 ggagaagcaa tagttaagta tggagaagag aagaatataa aatttgaaaa agttgataat
    16801 tttaaagcta taccaggtgc tggtatacaa gttactatta atgatgaaag tatattactt
    16861 ggaaatagaa agcttatgaa tgacaataat ataaagcttg gggatttaga agaaaaatca
    16921 aatatattgg caagccaagg taaaacacct atgtatatag ctgtagatgg aaatttatca
    16981 ggtataatag cagttgcaga tgtagtcaaa gaaagtagta aaaaagcaat agaaatactt
    17041 catgatatgg gaataaaagt tgcaatggta actggagata atgcgaaaac tgcaaatgct
    17101 atagcaaatc aagtaggtat agatatggtt ttggcagagg ttttaccaga agataagtca
    17161 aaagaagttg aaaaactaca aaatcaagga aagtttgttg caatggtagg ggatggaata
    17221 aatgatgccc cagctcttgc aaaagcagat atagggatag caataggaag tggaacggat
    17281 gtagccattg aatctgcgga tatagtactt atgaagagtg atttaattga tgttccaaca
    17341 gcaattaaac ttagtcatga aactataaaa aatataaaac aaaacctatt ttgggcattt
    17401 ggatataata caattggtat acctgtagca gcaggaatat tatatgtatt tggaggacct
    17461 ttattaaacc caatgattgc agcagcagca atgagcttaa gttcagtttc agtcgtatca
    17521 aatgcactta gacttaaaaa cttcaaggca tataagagag attagattaa taaattaaat
    17581 aaaatgtatc caaaagagct atctttaaat taaaaggatt aatttacaaa ttaagatagc
    17641 tcttttttca tgtaaaattc acaacaataa gataaaatat aagtaatata cgaaatttta
    17701 aataaaatag aaaggattga tagaatgaat tcgtcaatac ttgtaattga agatgattca
    17761 aatatacaag agttaatatc agaattttta agtgcagaag gttatcaagt tgatacagca
    17821 aatgatgggt tggaaggtat acaaaagttt aagcaaggaa gttatgattt agtaatatta
    17881 gatataatga tgccaaactt agatggttat ggagtttgta aaatgataag aaagtcatca
    17941 agcgttccaa ttatattttt aactgcttta aatgatgaag gagaccaact taaagggttt
    18001 gacttagaat gtgatgatta tataacaaaa ccattttcat ttaatcttct tataaaaaga
    18061 gtagaagcaa ttttaaggcg aagtaacaag actataaatg acaaatttat agtttttgaa
    18121 aaattaaaat tagatttaaa cacatatatt gcagagatag atggagaacc tatagaactt
    18181 acactaaaag agtttaatat attaaaagct ttgatagaaa agtatccaca agttataact
    18241 agggaaggtc ttttggatag tatatggggt tatgactatt atggagatac taggattgtt
    18301 gatgcacata taaaaaatat aagaaaaaaa atatcattac catatattaa aactgtaaaa
    18361 ggaataggat atacacttga gaaggatatt tgataagtgg gaaaagttaa gtataaagta
    18421 taagttattt tcaataacga catcattatt aatagcatta gctttaataa tatatctaat
    18481 tttatatttt ttattgccat catattatca tgagtataaa attgagtctc ttcaagaaag
    18541 tttgaaatct ttagtagata gttcaattca tttcgataca tatactttag aagaaagact
    18601 ttattatatg gctaaagacc aaaatttggc tattttatta aaagataacc aaggtaaaat
    18661 tgtatatggt aagaatgaag tagttatttt aagatatagt aagtacatga ttaatagtct
    18721 tgaggatgag tatagaactt ctatacctat atatactaaa gatgcaaaag atggtccata
    18781 tactttagaa ctcgttatgc cattacaacc aattgacgaa gcaaacgaag ttataagaaa
    18841 actaatgcca tacatcatat caatagcaat attgatagcg attattggag catatatata
    18901 ttcaattgta ataacaaagc ctcttataaa cataatagag agtgagagag aacaggaata
    18961 tagaaggaag gattttgttg ctacaatatc acatgaacta aaaactccaa taaccataat
    19021 aagtggtcaa attgaaggta tgatttatag tgtaggtaag tataaggata gggatactta
    19081 tctgaaaaaa tcgtatgagt gtacacaaga attaaaagat ttagtaaatg aaatgataga
    19141 ggtttcaaaa tcagaaatac ttgaaaaaga tttgaaattg gtatcaataa atataagtga
    19201 attattaaat agacttgtaa agagacaagt atttttaata gaagaaaaac atatgaaaac
    19261 tattttaaaa atagaagaaa atttggaaat taaagcagac caagagagaa taactaaggc
    19321 aatcaataat ataataaata atgccataaa atattctcct gaagaatcag agcttataat
    19381 tagactctat gataaaaata aacgaataag taaaaaaact tctaatcaaa gagtggtttt
    19441 agaaattgaa aatactggtg taactatcga gaaacgttat ttagaagaaa tatttaatcc
    19501 attttataga atagaaaaat ctcgttcaag aaaaactgga ggaagtggac ttggacttta
    19561 tatagtcagc caaattttta aaagtcatgg gtttgattat agcataaaaa acaaagaaaa
    19621 ctctgtagta ttcacagtag aatttaaaaa ttaattactt attataaaga atatataact
    19681 ttcaataata gttcatttta aaatcacaaa aaattcataa tgaaactgta ttatataaat
    19741 ataaagaagc ttaaaaccat aaaatacacc aactataatg atgagatttc cttacatcct
    19801 ccatataagt catcattata gtaacccaac aattaagtta ctatgaattt aaaaaataac
    19861 accgagcata taatctatgc ttagtgttat ttttattttg aaataaaaaa tatttaattt
    19921 attgaaatgt atagatttag atagtttaaa ctatatttaa gacttaaaaa ttataattga
    19981 tattacaaat aaatatatgt actttgggaa aaataaatat aggaagtatt atatttacag
    20041 aggaggtagt tttgatggat agattaaaaa gagatatgaa aaatatgaaa gaagatttaa
    20101 aagaaggtgt taaaaagaca gcttatgtta tgaaaaatac agctgaagat ttgaaagatg
    20161 atgcacaagg tgctatggta aacttagaaa tgaaaaaaga tgagatgatg gaaagatatg
    20221 aacaaaagaa attttctaaa gaattagaga agcaaatgaa gaatgaaatg aaataagctt
    20281 ttatttatga ataacaaatt attgtattca tataaaaagt agccagtaat attaaatagt
    20341 ttatttaagg aaatagactt tctaaaaata actgtattag atttagaaag tctatttcaa
    20401 attagtttta taaatagaca taaggataaa gtagatgtta tagaactaga ttttaaaaaa
    20461 tagatacta
//
LOCUS       DAEPXW010000072        20417 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.073, whole genome shotgun sequence.
ACCESSION   DAEPXW010000072 DAEPXW010000000
VERSION     DAEPXW010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.073"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            126..680
                     /gene="tcdR"
                     /locus_tag="KRM55_002585"
     CDS             126..680
                     /gene="tcdR"
                     /locus_tag="KRM55_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HBH1594808.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSIFEEDICFFGYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            998..8098
                     /gene="tcdB"
                     /locus_tag="KRM55_002586"
                     /gene_synonym="toxB"
     CDS             998..8098
                     /gene="tcdB"
                     /locus_tag="KRM55_002586"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HBH1594809.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGIASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYRFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDDKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8220..8720
                     /gene="tcdE"
                     /locus_tag="KRM55_002587"
     CDS             8220..8720
                     /gene="tcdE"
                     /locus_tag="KRM55_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBH1594810.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            8799..8960
                     /locus_tag="KRM55_002588"
     CDS             8799..8960
                     /locus_tag="KRM55_002588"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594811.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYIDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            9049..9231
                     /locus_tag="KRM55_002589"
     CDS             9049..9231
                     /locus_tag="KRM55_002589"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594812.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9448..17580
                     /gene="tcdA"
                     /locus_tag="KRM55_002590"
                     /gene_synonym="toxA"
     CDS             9448..17580
                     /gene="tcdA"
                     /locus_tag="KRM55_002590"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBH1594813.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17915..18613)
                     /gene="tcdC"
                     /locus_tag="KRM55_002591"
     CDS             complement(17915..18613)
                     /gene="tcdC"
                     /locus_tag="KRM55_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HBH1594814.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            19039..19284
                     /locus_tag="KRM55_002592"
     CDS             19039..19284
                     /locus_tag="KRM55_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBH1594815.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19502..19771)
                     /locus_tag="KRM55_002593"
     CDS             complement(19502..19771)
                     /locus_tag="KRM55_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1594816.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
BASE COUNT         8089 a         2295 c         3087 g         6946 t
ORIGIN      
        1 aatgtatatt ttcatataaa atttaattta tttgccgatt atataattat aatgactgat
       61 ttaattccaa tgttgtcaaa attttcaaat aaatcatcat tataaatata agagaggatg
      121 attttatgca aaagtctttt tatgaattaa ttgttttagc aagaaataac tcagtagatg
      181 atttgcaaga aattttattt atgtttaagc cattagtaaa aaaacttagt agagttttac
      241 attatgaaga gggagaaaca gatttaataa tattttttat tgaattaata aaaaatatta
      301 aattaagtag cttttcagaa aaaagcgatg ctattatagt caaatatatt cataaatcat
      361 tactgaataa gacttttgag ttgtctagaa gatattctaa aatgaagttt aattttgtag
      421 aatttgatga aaatatctta aatatgaaaa ataattatca aagtaagtct atttttgagg
      481 aagatatttg ttttttcgga tatattttga aagaattatc tggtattcaa agaaaagtta
      541 ttttttataa atatttaaaa ggatattctg atagagaaat atcagtgaaa ttaaaaatat
      601 ctagacaagc tgttaataag gctaaaaata gagcatttaa aaaaataaaa aaagactatg
      661 aaaattattt taacttgtaa ttaatgagtt taaagaaata tttacaatag aaatcaaatt
      721 ttataattaa ctttattgta aaattaataa cttaatctaa gaatatctta atttttatat
      781 tttatataga acaatgttta catatttatt tcagacaacg tctttattca atcgaagagc
      841 aaattaatca actgagtgtc ttaaatttaa aatgttagga agtgaatgta tatgaaaacc
      901 taagtagata ttagtatatt ttataaatag aaaggaggat atataaaaga gttttagcat
      961 ttagatgtaa aaatattata gtaaaggaga aaattttatg agtttagtta atagaaaaca
     1021 gttagaaaaa atggcaaatg taagatttcg tactcaagaa gatgaatatg ttgcaatatt
     1081 ggatgcttta gaagaatatc ataatatgtc agagaatact gtagtcgaaa aatatttaaa
     1141 attaaaagat ataaatagtt taacagatat ttatatagat acatataaaa aatctggtag
     1201 aaataaagcc ttaaaaaaat ttaaggaata tctagttaca gaagtattag agctaaagaa
     1261 taataattta actccagttg agaaaaattt acattttgtt tggattggag gtcaaataaa
     1321 tgacactgct attaattata taaatcaatg gaaagatgta aatagtgatt ataatgttaa
     1381 tgttttttat gatagtaatg catttttgat aaacacattg aaaaaaactg tagtagaatc
     1441 agcaataaat gatacacttg aatcatttag agaaaactta aatgacccta gatttgacta
     1501 taataaattc ttcagaaaac gtatggaaat aatttatgat aaacagaaaa atttcataaa
     1561 ctactataaa gctcaaagag aagaaaatcc tgaacttata attgatgata ttgtaaagac
     1621 atatctttca aatgagtatt caaaggagat agatgaactt aatacctata ttgaagaatc
     1681 cttaaataaa attacacaga atagtggaaa tgatgttaga aactttgaag aatttaaaaa
     1741 tggagagtca ttcaacttat atgaacaaga gttggtagaa aggtggaatt tagctgctgc
     1801 ttctgacata ttaagaatat ctgcattaaa agaaattggt ggtatgtatt tagatgttga
     1861 tatgttacca ggaatacaac cagacttatt tgagtctata gagaaaccta gttcagtaac
     1921 agtggatttt tgggaaatga caaagttaga agctataatg aaatacaaag aatatatacc
     1981 agaatatacc tcagaacatt ttgacatgtt agacgaagaa gttcaaagta gttttgaatc
     2041 tgttctagct tctaagtcag ataaatcaga aatattctca tcacttggtg atatggaggc
     2101 atcaccacta gaagttaaaa ttgcatttaa tagtaagggt attataaatc aagggctaat
     2161 ttctgtgaaa gactcatatt gtagcaattt aatagtaaaa caaatcgaga atagatataa
     2221 aatattgaat aatagtttaa atccagctat tagcgaggat aatgatttta atactacaac
     2281 gaataccttt attgatagta taatggctga agctaatgca gataatggta gatttatgat
     2341 ggaactagga aagtatttaa gagttggttt cttcccagat gttaaaacta ctattaactt
     2401 aagtggccct gaagcatatg cggcagctta tcaagattta ttaatgttta aagaaggcag
     2461 tatgaatatc catttgatag aagctgattt aagaaacttt gaaatctcta aaactaatat
     2521 ttctcaatca actgaacaag aaatggctag cttatggtca tttgacgatg caagagctaa
     2581 agctcaattt gaagaatata aaaggaatta ttttgaaggt tctcttggtg aagatgataa
     2641 tcttgatttt tctcaaaata tagtagttga caaggagtat cttttagaaa aaatatcttc
     2701 attagcaaga agttcagaga gaggatatat acactatatt gttcagttac aaggagataa
     2761 aattagttat gaagcagcat gtaacttatt tgcaaagact ccttatgata gtgtactgtt
     2821 tcagaaaaat atagaagatt cagaaattgc atattattat aatcctggag atggtgaaat
     2881 acaagaaata gacaagtata aaattccaag tataatttct gatagaccta agattaaatt
     2941 aacatttatt ggtcatggta aagatgaatt taatactgat atatttgcag gttttgatgt
     3001 agattcatta tccacagaaa tagaagcagc aatagattta gctaaagagg atatttctcc
     3061 taagtcaata gaaataaatt tattaggatg taatatgttt agctactcta tcaacgtaga
     3121 ggagacttat cctggaaaat tattacttaa agttaaagat aaaatatcag aattaatgcc
     3181 atctataagt caagactcta ttatagtaag tgcaaatcaa tatgaagtta gaataaatag
     3241 tgaaggaaga agagaattat tagaccattc tggtgaatgg ataaacaaag aagaaagtat
     3301 tataaaggat atttcatcaa aagaatatat atcatttaat cctaaagaaa ataaaattac
     3361 agtaaaatct aaaaatttac ctgagctatc tacattatta caagaaatta gaaataattc
     3421 taattcaagt gatattgaac tagaagaaaa agtaatgtta acagaatgtg agataaatgt
     3481 tatttcaaat atagatacgc aaattgttga ggaaaggatt gaagaagcta agaatttaac
     3541 ttctgactct attaattata taaaagatga atttaaacta atagaatcta tttctgatgc
     3601 actatgtgac ttaaaacaac agaatgaatt agaagattct cattttatat cttttgagga
     3661 catatcagag actgatgagg gatttagtat aagatttatt aataaagaaa ctggagaatc
     3721 tatatttgta gaaactgaaa aaacaatatt ctctgaatat gctaatcata taactgaaga
     3781 gatttctaag ataaaaggta ctatatttga tactgtaaat ggtaagttag taaaaaaagt
     3841 aaatttagat actacacacg aagtaaatac tttaaatgct gcatttttta tacaatcatt
     3901 aatagaatat aatagttcta aagaatctct tagtaattta agtgtagcaa tgaaagtcca
     3961 agtttacgct caattattta gtactggttt aaatactatt acagatgcag ccaaagttgt
     4021 tgaattagta tcaactgcat tagatgaaac tatagactta cttcctacat tatctgaagg
     4081 attacctata attgcaacta ttatagatgg tgtaagttta ggtgcagcaa tcaaagagct
     4141 aagtgaaacg agtgacccat tattaagaca agaaatagaa gctaagatag gtataatggc
     4201 agtaaattta acaacagcta caactgcaat cattacttca tctttgggga tagctagtgg
     4261 atttagtata cttttagttc ctttagcagg aatttcagca ggtataccaa gcttagtaaa
     4321 caatgaactt gtacttcgag ataaggcaac aaaggttgta gattatttta aacatgtttc
     4381 attagttgaa actgaaggag tatttacttt attagatgat aaaataatga tgccacaaga
     4441 tgatttagtg atatcagaaa tagattttaa taataattca atagttttag gtaaatgtga
     4501 aatctggaga atggaaggtg gttcaggtca tactgtaact gatgatatag atcacttctt
     4561 ttcagcacca tcaataacat atagagagcc acacttatct atatatgacg tattggaagt
     4621 acaaaaagaa gaacttgatt tgtcaaaaga tttaatggta ttacctaatg ctccaaatag
     4681 agtatttgct tgggaaacag gatggacacc aggtttaaga agcttagaaa atgatggcac
     4741 aaaactgtta gaccgtataa gagataacta tgaaggtgag ttttattgga gatattttgc
     4801 ttttatagct gatgctttaa taacaacatt aaaaccaaga tatgaagata ctaatataag
     4861 aataaattta gatagtaata ctagaagttt tatagttcca ataataacta cagaatatat
     4921 aagagaaaaa ttatcatatt ctttctatgg ttcaggagga acttatgcat tgtctctttc
     4981 tcaatataat atgggtataa atatagaatt aagtgaaagt gatgtttgga ttatagatgt
     5041 tgataatgtt gtgagagatg taactataga atctgataaa attaaaaaag gtgatttaat
     5101 agaaggtatt ttatctacac taagtattga agagaataaa attatcttaa atagccatga
     5161 gattaatttt tctggtgagg taaatggaag taatggattt gtttctttaa cattttcaat
     5221 tttagaagga ataaatgcaa ttatagaagt tgatttatta tctaaatcat ataaattact
     5281 tatttctggc gaattaaaaa tattgatgtt aaattcaaat catattcaac agaaaataga
     5341 ttatatagga ttcaatagcg aattacagaa aaatatacca tatagatttg tagatagtga
     5401 aggaaaagag aatggtttta ttaatggttc aacaaaagaa ggtttatttg tatctgaatt
     5461 acctgatgta gttcttataa gtaaggttta tatggatgat agtaagcctt catttggata
     5521 ttatagtaat aatttgaaag atgtcaaagt tataactaaa gataatgtta atatattaac
     5581 aggttattat cttaaggatg atataaaaat ctctctttct ttgactctac aagatgaaaa
     5641 aactataaag ttaaatagtg tgcatttaga tgaaagtgga gtagctgaga ttttgaagtt
     5701 catgaataga aaaggtaata caaatacttc agattcttta atgagctttt tagaaagtat
     5761 gaatataaaa agtattttcg ttaatttctt acaatctaat attaagttta tattagatgc
     5821 taattttata ataagtggta ctacttctat tggccaattt gagtttattt gtgatgaaaa
     5881 tgataatata caaccatatt tcattaagtt taatacacta gaaactaatt atactttata
     5941 tgtaggaaat agacaaaata tgatagtgga accaaattat gatttagatg attctggaga
     6001 tatatcttca actgttatca atttctctca aaagtatctt tatggaatag acagttgtgt
     6061 taataaagtt gtaatttcac caaatattta tacagatgaa ataaatataa cgcctgtata
     6121 tgaaacaaat aatacttatc cagaagttat tgtattagat gcaaattata taaatgaaaa
     6181 aataaatgtt aatatcaatg atctatctat acgatatgta tggagtaatg atggtaatga
     6241 ttttattctt atgtcaacta gtgaagaaaa taaggtgtca caagttaaaa taagattcgt
     6301 taatgttttt aaagataaga ctttggcaaa taagctatct tttaacttta gtgataaaca
     6361 agatgtacct gtaagtgaaa taatcttatc atttacacct tcatattatg aggatggatt
     6421 gattggctat gatttgggtc tagtttcttt atataatgag aaattttata ttaataactt
     6481 tggaatgatg gtatctggat taatatatat taatgattca ttatattatt ttaaaccacc
     6541 agtaaataat ttgataactg gatttgtgac tgtaggcgat gataaatact actttaatcc
     6601 aattaatggt ggagctgctt caattggaga gacaataatt gatgacaaaa attattattt
     6661 caaccaaagt ggagtgttac aaacaggtgt atttagtaca gaagatggat ttaaatattt
     6721 tgccccagct aatacacttg atgaaaacct agaaggagaa gcaattgatt ttactggaaa
     6781 attaattatt gacgaaaata tttattattt tgatgataat tatagaggag ctgtagaatg
     6841 gaaagaatta gatggtgaaa tgcactattt tagcccagaa acaggtaaag cttttaaagg
     6901 tctaaatcaa ataggtgatg ataaatacta tttcaattct gatggagtta tgcaaaaagg
     6961 atttgttagt ataaatgata ataaacacta ttttgatgat tctggtgtta tgaaagtagg
     7021 ttacactgaa atagatggca agcatttcta ctttgctgaa aacggagaaa tgcaaatagg
     7081 agtatttaat acagaagatg gatttaaata ttttgctcat cataatgaag atttaggaaa
     7141 tgaagaaggt gaagaaatct catattctgg tatattaaat ttcaataata aaatttacta
     7201 ttttgatgat tcatttacag ctgtagttgg atggaaagat ttagaggatg gttcaaagta
     7261 ttattttgat gaagatacag cagaagcata tataggtttg tcattaataa atgatggtca
     7321 atattatttt aatgatgatg gaattatgca agttggattt gtcactataa atgataaagt
     7381 cttctacttc tctgactctg gaattataga atctggagta caaaacatag atgacaatta
     7441 tttctatata gatgataatg gtatagttca aattggtgta tttgatactt cagatggata
     7501 taaatatttt gcacctgcta atactgtaaa tgataatatt tacggacaag cagttgaata
     7561 tagtggttta gttagagttg gggaagatgt atattatttt ggagaaacat atacaattga
     7621 gactggatgg atatatgata tggaaaatga aagtgataaa tattatttca atccagaaac
     7681 taaaaaagca tgcaaaggta ttaatttaat tgatgatata aaatattatt ttgatgagaa
     7741 gggcataatg agaacgggtc ttatatcatt tgaaaataat aattattact ttaatgagaa
     7801 tggtgaaatg caatttggtt atataaatat agaagataag atgttctatt ttggtgaaga
     7861 tggtgtcatg cagattggag tatttaatac accagatgga tttaaatact ttgcacatca
     7921 aaatactttg gatgagaatt ttgagggaga atcaataaac tatactggtt ggttagattt
     7981 agatgaaaag agatattatt ttacagatga atatattgca gcaactggtt cagttattat
     8041 tgatggtgag gagtattatt ttgatcctga tacagctcaa ttagtgatta gtgaatagat
     8101 aaaaatatgt taaatatatc ctcttatact taaatatata aaaataaaca aaatgataca
     8161 ctacataaag tgttctatct aatatgaaga tttaccaata aaaaggtgga ctatgatgaa
     8221 tgcacagtag ttcacctttt tatatttcta atggtaacaa aatatttttt tatataaacc
     8281 taggaggcgt tatgaatatg acaatatctt ttttatcaga gcatatattt ataaagttag
     8341 taattttaac tatatcattt gatacattat taggatgttt aagtgcaata aaaagtcgta
     8401 aatttaattc tagttttgga atagatggag gaatcagaaa agtagcaatg atagcatgta
     8461 tatttttttt atcagtagtt gacattctta caaagtttaa ctttttattt atgttaccac
     8521 aagattgtat caatttttta agactaaaac atcttggaat atctgaattt ttctctattt
     8581 tatttatttt atatgaaagt gtaagtatat taaaaaatat gtgcttatgt ggattaccag
     8641 tacctaagag attaaaggaa aaaatagcaa ttttactaga tgcaatgaca gatgaaatga
     8701 atgctaagga tgaaaagtaa gtaatggtag atataataaa gatattaaca aataaaaagt
     8761 gttatccaaa taagaatagc tgaaagttat cataattcat gaaactaata atgaaaacga
     8821 gggagcagat gccaagagac acacaagtat taaatacata taatttcgaa gcaagtgttc
     8881 attactatat agatgacaag gtagtatatc aaacattggt tcacaaagat ggtgcatggt
     8941 cagttggtaa aatctattaa gctacattag ttacagatat cacaaactat aatagttaaa
     9001 catagaaata tgtgtaaatt gtgatggaaa ttattcaaaa acacaaaaat acgtgatgaa
     9061 ggacaaaatg atatagaaaa taagtatcaa accttaataa atgatttaat tgatagttta
     9121 aaagttatag gaaaaatata taaagaaata aaaacattaa aaaaatataa gatatgttta
     9181 caaattacta tcagacaatc tccttatcta atagaagagt caattaacta attgagtatc
     9241 tttaaattga aatgttagga agtgatttaa atatgaaaac ttaaattata aaaaatcaat
     9301 attaatttat ttttaaaaaa tagaaaggag tgtataagat ttattttcaa agtttaaaaa
     9361 caagaaaatc aatttaaatt tcagaaggaa taaatgtggt tatagaagtg gatttattat
     9421 caaaaataat aatactagga ggtttttatg tctttaatat ctaaagaaga gttaataaaa
     9481 ctcgcatata gcattagacc aagagaaaat gagtataaaa ctatactaac taatttagac
     9541 gaatataata agttaactac aaacaataat gaaaataaat atttacaatt aaaaaaacta
     9601 aatgaatcaa ttgatgtttt tatgaataaa tataaaactt caagcagaaa tagagcactc
     9661 tctaatctaa aaaaagatat attaaaagaa gtaattctta ttaaaaattc caatacaagc
     9721 cctgtagaaa aaaatttaca ttttgtatgg ataggtggag aagtcagtga tattgctctt
     9781 gaatacataa aacaatgggc tgatattaat gcagaatata atattaaact gtggtatgat
     9841 agtgaagcat tcttagtaaa tacactaaaa aaggctatag ttgaatcttc taccactgaa
     9901 gcattacagc tactagagga agagattcaa aatcctcaat ttgataatat gaaattttac
     9961 aaaaaaagga tggaatttat atatgataga caaaaaaggt ttataaatta ttataaatct
    10021 caaatcaata aacctacagt acctacaata gatgatatta taaagtctca tctagtatct
    10081 gaatataata gagatgaaac tgtattagaa tcatatagaa caaattcttt gagaaaaata
    10141 aatagtaatc atgggataga tatcagggct aatagtttgt ttacagaaca agagttatta
    10201 aatatttata gtcaggagtt gttaaatcgt ggaaatttag ctgcagcatc tgacatagta
    10261 agattattag ccctaaaaaa ttttggcgga gtatatttag atgttgatat gcttccaggt
    10321 attcactctg atttatttaa aacaatatct agacctagct ctattggact agaccgttgg
    10381 gaaatgataa aattagaggc tattatgaag tataaaaaat atataaataa ttatacatca
    10441 gaaaactttg ataaacttga tcaacaatta aaagataatt ttaaactcat tatagaaagt
    10501 aaaagtgaaa aatctgagat attttctaaa ttagaaaatt taaatgtatc tgatcttgaa
    10561 attaaaatag ctttcgcttt aggcagtgtt ataaatcaag ccttgatatc aaaacaaggt
    10621 tcatatctta ctaacctagt aatagaacaa gtaaaaaata gatatcaatt tttaaaccaa
    10681 caccttaacc cagccataga gtctgataat aacttcacag atactactaa aatttttcat
    10741 gattcattat ttaattcagc taccgcagaa aactctatgt ttttaacaaa aatagcacca
    10801 tacttacaag taggttttat gccagaagct cgctccacaa taagtttaag tggtccagga
    10861 gcttatgcgt cagcttacta tgatttcata aatttacaag aaaatactat agaaaaaact
    10921 ttaaaagcat cagatttaat agaatttaaa ttcccagaaa ataatctatc tcaattgaca
    10981 gaacaagaaa taaatagtct atggagcttt gatcaagcaa gtgcaaaata tcaatttgag
    11041 aaatatgtaa gagattatac tggtggatct ctttctgaag acaatggggt agactttaat
    11101 aaaaatactg ccctcgacaa aaactattta ttaaataata aaattccatc aaacaatgta
    11161 gaagaagctg gaagtaaaaa ttatgttcat tatatcatac agttacaagg agatgatata
    11221 agttatgaag caacatgcaa tttattttct aaaaatccta aaaatagtat tattatacaa
    11281 cgaaatatga atgaaagtgc aaaaagctac tttttaagtg atgatggaga atctatttta
    11341 gaattaaata aatataggat acctgaaaga ttaaaaaata aggaaaaagt aaaagtaacc
    11401 tttattggac atggtaaaga tgaattcaac acaagcgaat ttgctagatt aagtgtagat
    11461 tcactttcca atgagataag ttcattttta gataccataa aattagatat atcacctaaa
    11521 aatgtagaag taaacttact tggatgtaat atgtttagtt atgattttaa tgttgaagaa
    11581 acttatcctg ggaagttgct attaagtatt atggacaaaa ttacttccac tttacctgat
    11641 gtaaataaaa attctattac tataggagca aatcaatatg aagtaagaat taatagtgag
    11701 ggaagaaaag aacttctggc tcactcaggt aaatggataa ataaagaaga agctattatg
    11761 agcgatttat ctagtaaaga atacattttt tttgattcta tagataataa gctaaaagca
    11821 aagtccaaga atattccagg attagcatca atatcagaag atataaaaac attattactt
    11881 gatgcaagtg ttagtcctga tacaaaattt attttaaata atcttaagct taatattgaa
    11941 tcttctattg gtgattacat ttattatgaa aaattagagc ctgttaaaaa tataattcac
    12001 aattctatag atgatttaat agatgagttc aatctacttg aaaatgtatc tgatgaatta
    12061 tatgaattaa aaaaattaaa taatctagat gagaagtatt taatatcttt tgaagatatc
    12121 tcaaaaaata attcaactta ctctgtaaga tttattaaca aaagtaatgg tgagtcagtt
    12181 tatgtagaaa cagaaaaaga aattttttca aaatatagcg aacatattac aaaagaaata
    12241 agtactataa agaatagtat aattacagat gttaatggta atttattgga taatatacag
    12301 ttagatcata cttctcaagt taatacatta aacgcagcat tctttattca atcattaata
    12361 gattatagta gcaataaaga tgtactgaat gatttaagta cctcagttaa ggttcaactt
    12421 tatgctcaac tatttagtac aggtttaaat actatatatg actctatcca attagtaaat
    12481 ttaatatcaa atgcagtaaa tgatactata aatgtactac ctacaataac agaggggata
    12541 cctattgtat ctactatatt agacggaata aacttaggtg cagcaattaa ggaattacta
    12601 gacgaacatg acccattact aaaaaaagaa ttagaagcta aggtgggtgt tttagcaata
    12661 aatatgtcat tatctatagc tgcaactgta gcttcaattg ttggaatagg tgctgaagtt
    12721 actattttct tattacctat agctggtata tctgcaggaa taccttcatt agttaataat
    12781 gaattaatat tgcatgataa ggcaacttca gtggtaaact attttaatca tttgtctgaa
    12841 tctaaaaaat atggccctct taaaacagaa gatgataaaa ttttagttcc tattgatgat
    12901 ttagtaatat cagaaataga ttttaataat aattcgataa aactaggaac atgtaatata
    12961 ttagcaatgg aggggggatc aggacacaca gtgactggta atatagatca ctttttctca
    13021 tctccatcta taagttctca tattccttca ttatcaattt attctgcaat aggtatagaa
    13081 acagaaaatc tagatttttc aaaaaaaata atgatgttac ctaatgctcc ttcaagagtg
    13141 ttttggtggg aaactggagc agttccaggt ttaagatcat tggaaaatga cggaactaga
    13201 ttacttgatt caataagaga tttataccca ggtaaatttt actggagatt ctatgctttt
    13261 ttcgattatg caataactac attaaaacca gtttatgaag acactaatat taaaattaaa
    13321 ctagataaag atactagaaa cttcataatg ccaactataa ctactaacga aattagaaac
    13381 aaattatctt attcatttga tggagcagga ggaacttact ctttattatt atcttcatat
    13441 ccaatatcaa cgaatataaa tttatctaaa gatgatttat ggatatttaa tattgataat
    13501 gaagtaagag aaatatctat agaaaatggt actattaaaa aaggaaagtt aataaaagat
    13561 gttttaagta aaattgatat aaataaaaat aaacttatta taggcaatca aacaatagat
    13621 ttttcaggcg atatagataa taaagataga tatatattct tgacttgtga gttagatgat
    13681 aaaattagtt taataataga aataaatctt gttgcaaaat cttatagttt gttattgtct
    13741 ggggataaaa attatttgat atccaattta tctaatacta ttgagaaaat caatacttta
    13801 ggcctagata gtaaaaatat agcgtacaat tacactgatg aatctaataa taaatatttt
    13861 ggagctatat ctaaaacaag tcaaaaaagc ataatacatt ataaaaaaga cagtaaaaat
    13921 atattagaat tttataatga cagtacatta gaatttaaca gtaaagattt tattgctgaa
    13981 gatataaatg tatttatgaa agatgatatt aatactataa caggaaaata ctatgttgat
    14041 aataatactg ataaaagtat agatttctct atttctttag ttagtaaaaa tcaagtaaaa
    14101 gtaaatggat tatatttaaa tgaatccgta tactcatctt accttgattt tgtgaaaaat
    14161 tcagatggac accataatac ttctaatttt atgaatttat ttttggacaa tataagtttc
    14221 tggaaattgt ttgggtttga aaatataaat tttgtaatcg ataaatactt tacccttgtt
    14281 ggtaaaacta atcttggata tgtagaattt atttgtgaca ataataaaaa tatagatata
    14341 tattttggtg aatggaaaac atcgtcatct aaaagcacta tatttagcgg aaatggtaga
    14401 aatgttgtag tagagcctat atataatcct gatacgggtg aagatatatc tacttcacta
    14461 gatttttcct atgaacctct ctatggaata gatagatata tcaataaagt attgatagca
    14521 cctgatttat atacaagttt aataaatatt aataccaatt attattcaaa tgagtactac
    14581 cctgagatta tagttcttaa cccaaataca ttccacaaaa aagtaaatat aaatttagat
    14641 agttcttctt ttgagtataa atggtctaca gaaggaagtg actttatttt agttagatac
    14701 ttagaagaaa gtaataaaaa aatattacaa aaaataagaa tcaaaggtat cttatctaat
    14761 actcaatcat ttaataaaat gagtatagat tttaaagata ttaaaaaact atcattagga
    14821 tatataatga gtaattttaa atcatttaat tctgaaaatg aattagatag agatcattta
    14881 ggatttaaaa taatagataa taaaacttat tactatgatg aagatagtaa attagttaaa
    14941 ggattaatca atataaataa ttcattattc tattttgatc ctatagaatt taacttagta
    15001 actggatggc aaactatcaa tggtaaaaaa tattattttg atataaatac tggagcagct
    15061 ttaactagtt ataaaattat taatggtaaa cacttttatt ttaataatga tggtgtgatg
    15121 cagttgggag tatttaaagg acctgatgga tttgaatatt ttgcacctgc caatactcaa
    15181 aataataaca tagaaggtca ggctatagtt tatcaaagta aattcttaac tttgaatggc
    15241 aaaaaatatt attttgataa tgactcaaaa gcagtcactg gatggagaat tattaacaat
    15301 gagaaatatt actttaatcc taataatgct attgctgcag tcggattgca agtaattgac
    15361 aataataagt attatttcaa tcctgacact gctatcatct caaaaggttg gcagactgtt
    15421 aatggtagta gatactactt tgatactgat accgctattg cctttaatgg ttataaaact
    15481 attgatggta aacactttta ttttgatagt gattgtgtag tgaaaatagg tgtgtttagt
    15541 acctctaatg gatttgaata ttttgcacct gctaatactt ataataataa catagaaggt
    15601 caggctatag tttatcaaag taaattctta actttgaatg gtaaaaaata ttactttgat
    15661 aataactcaa aagcagttac cggatggcaa actattgata gtaaaaaata ttactttaat
    15721 actaacactg ctgaagcagc tactggatgg caaactattg atggtaaaaa atattacttt
    15781 aatactaaca ctgctgaagc agctactgga tggcaaacta ttgatggtaa aaaatattac
    15841 tttaatacta acactgctat agcttcaact ggttatacaa ttattaatgg taaacatttt
    15901 tattttaata ctgatggtat tatgcagata ggagtgttta aaggacctaa tggatttgaa
    15961 tattttgcac ctgctaatac ggatgctaac aacatagaag gtcaagctat actttaccaa
    16021 aatgaattct taactttgaa tggtaaaaaa tattactttg gtagtgactc aaaagcagtt
    16081 actggatgga gaattattaa caataagaaa tattacttta atcctaataa tgctattgct
    16141 gcaattcatc tatgcactat aaataatgac aagtattact ttagttatga tggaattctt
    16201 caaaatggat atattactat tgaaagaaat aatttctatt ttgatgctaa taatgaatct
    16261 aaaatggtaa caggagtatt taaaggacct aatggatttg agtattttgc acctgctaat
    16321 actcacaata ataacataga aggtcaggct atagtttacc agaacaaatt cttaactttg
    16381 aatggcaaaa aatattattt tgataatgac tcaaaagcag ttactggatg gcaaaccatt
    16441 gatggtaaaa aatattactt taatcttaac actgctgaag cagctactgg atggcaaact
    16501 attgatggta aaaaatatta ctttaatctt aacactgctg aagcagctac tggatggcaa
    16561 actattgatg gtaaaaaata ttactttaat actaacactt tcatagcctc aactggttat
    16621 acaagtatta atggtaaaca tttttatttt aatactgatg gtattatgca gataggagtg
    16681 tttaaaggac ctaatggatt tgaatacttt gcacctgcta atactcataa taataacata
    16741 gaaggtcaag ctatacttta ccaaaataaa ttcttaactt tgaatggtaa aaaatattac
    16801 tttggtagtg actcaaaagc agttaccgga ttgcgaacta ttgatggtaa aaaatattac
    16861 tttaatacta acactgctgt tgcagttact ggatggcaaa ctattaatgg taaaaaatac
    16921 tactttaata ctaacacttc tatagcttca actggttata caattattag tggtaaacat
    16981 ttttatttta atactgatgg tattatgcag ataggagtgt ttaaaggacc tgatggattt
    17041 gaatactttg cacctgctaa tacagatgct aacaatatag aaggtcaagc tatacgttat
    17101 caaaatagat tcctatattt acatgacaat atatattatt ttggtaataa ttcaaaagcg
    17161 gctactggtt gggtaactat tgatggtaat agatattact tcgagcctaa tacagctatg
    17221 ggtgcgaatg gttataaaac tattgataat aaaaattttt actttagaaa tggtttacct
    17281 cagataggag tgtttaaagg gtctaatgga tttgaatact ttgcacctgc taatacggat
    17341 gctaacaata tagaaggtca agctatacgt tatcaaaata gattcctaca tttacttgga
    17401 aaaatatatt actttggtaa taattcaaaa gcagttactg gatggcaaac tattaatggt
    17461 aaagtatatt actttatgcc tgatactgct atggctgcag ctggtggact tttcgagatt
    17521 gatggtgtta tatatttctt tggtgttgat ggagtaaaag cccctgggat atatggctaa
    17581 aatatatgtt tgataaaaaa ttattcctgt gctactaaga aattattttt atataataaa
    17641 tattgagatt taattaaaag tcatgtgtta ttgtaataca tgacttttag ttaaaatttt
    17701 tctatcattt aataatctat tattcttgac tattttataa taaaattcat atatggaaat
    17761 attaatacta aataattaat agttgataaa aaatagataa tatgctaaaa gcaaaaacta
    17821 atttagagcc ttgtaactgt ttatttgcaa ttataaaaac atctttaaac atattgacta
    17881 taatataaaa tattaactat aatacaaaac aatattaatt aattttctct acagctatcc
    17941 ctggtatagt tatatttcca cccatagttg attcataagt tatagttcca gcacttatac
    18001 ctcttatagt tatgtaatca tcctctaata ctcttgaagg agttattgat tttttataac
    18061 tacatagtac aaccttatca taatttccag acacagctaa tcttatttgc acctcatcac
    18121 catcttcaat aacttgaata accttacctt caaattttac ctttttgtac ttataatcat
    18181 caggtgttct agctaattgg tcataagtaa taccagtatc atatcctttc ttctcctctt
    18241 cttctttttt gcgttgttct tcagcctttt tagcttcttc agctttttta gcttcttcag
    18301 ctttacgttg attttcagct tcaatagctt tcttttcgtc gtctttcatt ttgaaccatg
    18361 gttcagcatc agacaatttg ctatttaaag tttctatttc tgttttttga gaatctataa
    18421 ctgatgtttg gttagaaatg acctcctcat ggtcttcaga acaagctggt gaggatatat
    18481 tgccaaaaaa cacgcctaaa ataaatgcca gtagagcaat accctttgtg ctcttaaaga
    18541 atttaattat tttcttagag cttccttttc cttcattact aaattcgtta ccctcatttt
    18601 ttttagaaaa cataatacaa tctccctttt attagatata ttttatttta aaagttaaaa
    18661 acttaaaata actagttgac taaaaattat atattcatat tttcctaaaa tatatttccc
    18721 ctaagcataa ttttacaaaa taaagtaaga agattcaata tattttgaaa aaataagata
    18781 aaaatgtcag attataatat aattttcttg aaggtgaatt ttatatatta aattaaacat
    18841 aaagtatttt atttgtataa aactatatta tgatgtaatt aagtgactca gtgatttaga
    18901 ggtggtaaaa tatatatata tgaaagagca taaataaatt gatataataa aaaattaaat
    18961 attaaatatt aactataata aaaaaatatc tggtaatagg tataatataa aaagaatata
    19021 ccagaaagaa ggtgaagtat gggagaacta caaaaaattc caggggtagg gaaagcaaca
    19081 gaaaaatctt taatcatgtt aggatataca actattaaat cacttaaaga tgcaaaccca
    19141 gcacaaatgt atgaaaagga atgtttaatg cgtggacagc acatagacag atgtcagtta
    19201 tatgtataca gatgtgcagt atattttgca tcaactgaaa atccagaacc agaaaaatta
    19261 aagtggtggt attggaaaga ttaaaaaatc aaaaaagtta gacataaaaa agagttgaat
    19321 atccgtttta aataataaaa actaatactc aactcttttt tagtcgtaaa ttttatgtaa
    19381 atctatttgt atggctaaat atacccatca ataaatgtat aaatatacta atcaacaaat
    19441 gactaaacat actacctaac aaaggattaa ataaattcct taacaaagca ttctaaaaca
    19501 attaattaga aactgtttct tcaagccatt ttctacattg ctcaatattt accatagggt
    19561 caaaaccttg gtcttttccc ttatttaaaa gcatatcaca agggaaagta tcacattcac
    19621 cacaatgatt aagttcctta ctttcacagc aagttttaac cttacattct ccaccccaaa
    19681 atggtttttc catagttggg caaccagtgc aatttacttg ttcttttttt gtacaactgt
    19741 cacaacagac accacatctt gattcaaaca tattcaaaca tcctttccat tatttaaaaa
    19801 tattataaaa tgattttaga tgaatacaaa agtgcaaata gttgatttta ggtcatctaa
    19861 atgttaaaca taaaattatt agtactggta aatttataaa aactattcca aaaatctttt
    19921 tgaatatttc aaaacacaat aaattacttc aaatcccctt gaatatattt tacagcatta
    19981 tagattgctt taaatctctt tgaatattct acaagactat agattagttt aaatcccttt
    20041 gaatatattt tacaacatta tagattgttt taaatctctt tgaatattct acaagactat
    20101 agattagttt aaatcccttt gaatatttca aaacaccata gattacttta aatccctttg
    20161 aatgttctat aacactataa attactttta acttttatat aaccataaag tttttatctg
    20221 gcactttaaa tggagtttta tatcaaattt gccttccatc gaataaccaa acttaattta
    20281 attacacatt ccaagagtca aatattcatt caatatattt gataattcta tgttatagct
    20341 ataattaaat atagattatt aaagttaaat atttatttaa tatattgaat gattttttac
    20401 ctatatttaa ttaagtt
//
LOCUS       DAEPXW010000073        18997 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.074, whole genome shotgun sequence.
ACCESSION   DAEPXW010000073 DAEPXW010000000
VERSION     DAEPXW010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18997
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.074"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(49..585)
                     /locus_tag="KRM55_002594"
     CDS             complement(49..585)
                     /locus_tag="KRM55_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBH1594817.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(603..1916)
                     /locus_tag="KRM55_002595"
     CDS             complement(603..1916)
                     /locus_tag="KRM55_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBH1594818.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2271..2711
                     /locus_tag="KRM55_002596"
     CDS             2271..2711
                     /locus_tag="KRM55_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH1594819.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2896..3084)
                     /locus_tag="KRM55_002597"
     CDS             complement(2896..3084)
                     /locus_tag="KRM55_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594820.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            4132..4527
                     /locus_tag="KRM55_002598"
     CDS             4132..4527
                     /locus_tag="KRM55_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594821.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4570..6669
                     /locus_tag="KRM55_002599"
     CDS             4570..6669
                     /locus_tag="KRM55_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBH1594822.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFIKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6894..12104)
                     /locus_tag="KRM55_002600"
     CDS             complement(6894..12104)
                     /locus_tag="KRM55_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH1594823.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKRLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDDSDRNYYYFDRYVFNHALNQKQAADDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKDGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILEFSHIYEIFYAVEKIEMQLNREILQKYYSFEKKNKAVLSMDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILKSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12119..14614)
                     /locus_tag="KRM55_002601"
     CDS             complement(12119..14614)
                     /locus_tag="KRM55_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1594824.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNMEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIER
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMDFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGKNGETGASGSNGADAGYTSYFHGQMFKGYFAKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15295..15582)
                     /locus_tag="KRM55_002602"
     CDS             complement(15295..15582)
                     /locus_tag="KRM55_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594825.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15602..15877)
                     /locus_tag="KRM55_002603"
     CDS             complement(15602..15877)
                     /locus_tag="KRM55_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594826.1"
                     /translation="MSLFAGGWSKFRAVEDEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16509..16688)
                     /locus_tag="KRM55_002604"
     CDS             complement(16509..16688)
                     /locus_tag="KRM55_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594827.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(16973..18448)
                     /locus_tag="KRM55_002605"
     CDS             complement(16973..18448)
                     /locus_tag="KRM55_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1594828.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIGFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRVKLDIL"
BASE COUNT         6314 a         3324 c         2079 g         7280 t
ORIGIN      
        1 ctttattttt taatatatat tttaaatttt cttttttaat aaatctattt aattttcttc
       61 ttctatatca gagccaaagg gaatccatgc attaccaaac tctttatctt taaataaata
      121 agctaatcca gttatttgct tcaatctaag aatttcatca acttccatac ccaggtgctt
      181 tgatatccat tcatcagatt ttccaatttc acaaagttca gttataattt tactcattaa
      241 atccacatta tgagaacctc ttgcacgatt gtgtcgaata gtacttgcca ttctttcatc
      301 aagagattta tcaattactg aaacaggaag aagtccattt tctctatcat atatatcctc
      361 attttcaagc attactctat atctatgaaa accatctaca ataatatact tatccttttc
      421 ctcattataa taacagacaa ttggcattgt atacccatct tcttttatac ttttatacaa
      481 caactgcatt tctggtgggg ctactgcatt tggattatag tcgttagatt ctatcttttc
      541 gattggcact gcgatgattc catatacagg acttttatat tccatagcat cttaactcct
      601 atctaatgaa ttttttcata tttcttctta atatattccg ttctaattct ctgttctttt
      661 gtaggaccaa atcccataaa tctacacata tggtcatttt ttaaaataca ataacacatt
      721 cttttccaac ttggtatatc tttggtaaat ttaatatcat ctgtatcatc aggtatatca
      781 tccaaaaata tgactctact ctttttatct tttgtatgat ttgaaactcc atttaattct
      841 attttataac cttttctcaa caattcacgt ataactattt ctgacaaacc accacctgta
      901 ttctgccaaa actcaataga tgttgaaaat tttttaatat agctattcct tatattttca
      961 ggtaaggtat caagcaaaaa atatgtgaaa cttttccatg tgtgtccata tggcaattta
     1021 acactacgat atcccatagc ttttgttttg ccataaatag aagtaaaatt aacaccttgt
     1081 actctagcaa ccaatttcac ccatacatct gggtccaata ttctgtataa atttaaactc
     1141 tcttttgctg aatcattaaa aggtgatgcc actctcattt ttcttggagc tactccagct
     1201 ttatagaata agtcataaat tttattatag tcatagtcaa atttatagtg tgctaaccat
     1261 atatcttcta tttcccaatc atatatagga gatgccgtcc agacattttt aaattcctta
     1321 gttatccagc actttccttt atatccatgc tgtttattca caatagaaca ataacgttgt
     1381 agagattctg ctgctcgtgt tcctaataag caaacaactt ttgcaccttc atgtatatct
     1441 ctaatccatc taccaaattg ttttgccaaa ctttcttgtc tcattttata tttataataa
     1501 gtaaaaggat tatttttttg atttattatg tattctttga ctggcatttc tcttacccat
     1561 aactcttctt tctcatcatc ccatggatac caatacattt cataatttcc tacagcagtt
     1621 cttgtagcca ttggtaaaca cacccaatat ggttcaatat cttcaatatt atcttcaaat
     1681 actttttcaa catattcagt agtcaaacta tattgagcct caaaatcttg atgaaatact
     1741 cctattttgg aacttatatt attctttctc ttataatcca aaactaaatt tagcagtaaa
     1801 ccactatctt ttcctccgct aaaagataca tagatataat caaattcatt aaaaagataa
     1861 gaaagtcttt cttgaaaagc ttcaaataca tcggattcta aatatctctt atccatttga
     1921 attatcccct ttcaattaga agtttataaa accttacaat gcaatattat tatgcttttt
     1981 tagcagtaat cagcataaat tatacattat ttaaatacac aaatccaact aaatacatat
     2041 aattataatg taattatact tttgtattat aaactatatt ttatcattat tttacatttt
     2101 tttccaatat atataattat catatttttc tattagctaa aactaattac cttatatttt
     2161 tacgtattgg tataataata cataaaaact tgaataatgc ataaaaactt gacatactgt
     2221 tgtcataatt actttgctat aattaaaagt aaaaatggag gtaaattcta atgtatgaac
     2281 gtatgcttga taaaagcaat aaaccctgtt tgtctcaaat aatagaatat ataggtaaag
     2341 atggatatgc acgattgtgt aagttggaaa cttacttgaa aactcaatat aatttatcaa
     2401 gagaacttcg atttcctttt ggaaacaatt atggttgggg ttacaaatat agccataaat
     2461 cttttcattt attttatgct ttttttgaaa aaggtgcatt tactgttctg attcagatag
     2521 gtgacaagca agttccagca gtagaaaaaa cgttggtagc tttgacacca aaagctaaag
     2581 agctctgggt cactcgttat ccttgtggca ataatggagg ttggattaag tatcgtattt
     2641 tagaagatgc agacttactt gatattattc aatatataag agcaaaaaaa tctccaccta
     2701 aacaaaatta acttttattt tttgtgattt aaatatagtg tatataaatt ccattctttc
     2761 catataaaaa aaataatata aaaaatatct attagtataa cttatttagt atgtcttatt
     2821 ctacttttta cagataatta aaaagtttta tcataaataa atcataacta gacatcctag
     2881 taaatcaaaa ttaatttatt cttttttatt agaatttttg ataacagtcc ctatacatat
     2941 gccaattatc attccaaaaa ttagaccata acacattgta atacctacat ttcctttaga
     3001 aatacctata gcacaaccta tagccattcc aagtatcatg cctataaaca tacatataat
     3061 aactaaattg ttgtttttat tcatagtttt tctccattca atatatttta aattgcctag
     3121 ctcgccttct tagcttaaaa caaagaaata taaattaact ttctttcatt ctaatatctg
     3181 cctgtataaa tgtcaaacaa cacatttctt gtcataacct cctctttttg aagtaaatac
     3241 aatctcccag acgcaataat atcaatttcc taaaaccatt taagtaactt ttatatttac
     3301 ataatattta caatcataaa ctatattgtt attcatttat acatcataaa cactccctcc
     3361 taatcattat tatacttaaa ataatgttca tttataataa tatatctaac gcactttaat
     3421 tgaaaaaact aaaactttgc ctttcattcc catatataaa taagtatact ttttgatgct
     3481 ctattacaaa tcaactaaat taattgatat aaattatcat tttctgttga aaataccatt
     3541 cgcacatgct atacttaatt gcataaatgg taataaatgt catatgattt tacaaatcta
     3601 ttaataacaa ttattacttt tactgtattt taaagttttt ggactaaata tcaagaactt
     3661 tctaaaatac aaagtacaaa aaatttatat aagttataaa tttatatgaa ctagataagc
     3721 tcaaacaata tgttatgtat aaactgtgta gtattcggtt ataaatttat ataaattata
     3781 taagctagat aaagtattac ctcaactata taaactacat atataaatta catatataag
     3841 ctagatatat aaattgcata tataagctat ataagaatta tttcaactat ataaactaca
     3901 tatataaatt acatacataa gctagatata taaactgcat atataagcta tataagaatt
     3961 atttcaacta tataaactac acacgtaaaa ttcatgtaaa tttactaata taaatcaaat
     4021 aaaattacta aactctctaa actaattttg taaaacatac tctattttta acatttgtta
     4081 ccttatacat aagtacaaac aaaatctaac taaatgaaag gataatgtaa aatgaatatt
     4141 ttaaaaatga aaaaaacagg gatattttta ggaggagtac tttttggtac tgtaggtgtt
     4201 aagatacttt caagtgattg tgttaaaaaa acttgcactc gtgcaacagc aggagcattg
     4261 aaagttaaag attctgttct tgaaacaact acgaaaattc aagaaaatgt agaagatatt
     4321 ttagctgaag caaaagaaat caacgagcaa gaagacttat ctacatctaa ggtaaacgtt
     4381 gtacaagata ctcttaaatg cgaacaagaa gttcttaaaa ctgaaactat aaaaactgta
     4441 gaagatacta attctaatag cattaaatgt gaagaaatca aagataacgt aattgaagaa
     4501 aaaaatagta cttgtacaac agaataaatt taatgattat tatgattaat aatatcagga
     4561 ggaagtaaat tgaattttta tataaaacac gaaataagag gtcgtatacg ctttgactta
     4621 caacttggca aattaaacaa caagcagtcc gatactctct tatattattt aacttctata
     4681 aatggtatta ccaaagcaaa agtttacgat agaactggtg atgcagtcat ttattacact
     4741 ggtgaaagag aatacataat aagagaaatc actaaattca gttttaacaa tagcaaaata
     4801 gaaaacctag ttcctgaaca taccagcagg gaattaaaca attattatag agacaaatta
     4861 gcaaataaac tgctagtcaa aagtatctcc aaaatatttt ttccaaagtc cttaagattt
     4921 tttttaattg gacttcattc tataaaatat tttaaaaaag gtctctcttc cctgctaaat
     4981 aaaaaaatag aagtttctgt tttagatgcc actgctatag gtatttctat ttttagaaaa
     5041 gatatcaata cggctggttc agttatgttt cttcttggta tcggtgaact attagaagaa
     5101 tggactagaa aaaaatctat agacgacttg gctcaaagta tgtcactaaa cattgaaaaa
     5161 gtatggttaa gaaaaggtga cactgaaatc ctaattccaa tttcagagat aaaggaagga
     5221 gatttagtaa gtgtaactat gggaaatatg attccattgg atggagttat agtatcagga
     5281 gaagcaatgg tcaatcaggc atcacttaca ggtgaatccc ttgcagttaa caaaaaagaa
     5341 ggctcttaca tatatgctgg aactgtaata gagcaaggca atattgttat gtgcgtcaag
     5401 gaaaaagctg gtactactag attccagaaa atagtaacta tgattgagga atctgaaaaa
     5461 ctaaaatctt ctgtagagag taaatttgaa catctagcag atacattagt tccatacagc
     5521 tttttaggaa gtatattaac ttatgcaatt actagaaacc ctataaaatc actctctata
     5581 ttaatggtag atttctcttg tgcattaaaa ctctctatcc ctatttcagt actatcagcc
     5641 atgagagaat gtaacaataa caacattact gtaaaaggtg gaaaattcct tgaaggtgtt
     5701 gcatgtgcag atactattgt atttgataag acaggcacat taacaaaagc tcaaccaact
     5761 gtttcagata taattacatt ccaaaattat aataaggagg atatgttaag acttgcagct
     5821 tgcttagaag aacacttccc acactccata gcaaatgcag tagtttacga agctgaaaaa
     5881 caagggctta gtcacaaaga aatgcataca gaggtagaat atattattgc tcatggcatt
     5941 tcaacaaaag ttgatgataa aaaggttgta ataggtagca aacattttgt atttgaagat
     6001 gagaagtgta ctatcccaga cggtgaggag gataagtaca ataatctatc agatgagtat
     6061 tcgcacctat ttatggcaat atcaggtaaa ttatcagcag ttatttgcat aaatgaccct
     6121 ttacgaaaag aagcaaaata tgtaatttca aatttaagag aatgcggaat aaaaaagatt
     6181 gtgatgatga ctggagatag cgaaaaaaca gctaaatcta tagcaagtaa agttggtgtt
     6241 gatgaatatt attcagaagt cttaccagaa gacaaagcca attttattaa aagtgaaaaa
     6301 ctcaaaggtc gcaaagtaat tatgattggt gatggaatca atgattctcc tgctatttca
     6361 gaatcagatg tcggaattgc aatgagtgaa ggtgctgaaa tagcaagaga gatttcagat
     6421 attaccatat cagcagataa tttgaataat ttaatcgttt taaagcagat tagtaataag
     6481 cttatgaaaa gagttgattt aagttctaag tttattatcg gttttaattt aggtctgatt
     6541 ttacttggtg taggtggatt tgttagacca agtacatctg cctttttaca caacgcatct
     6601 actgtcggaa taagtttaaa cagtatgaca aatttattgg aaaacaccaa tacttataac
     6661 taccattaat ctccattaca taaaacatat gatataaaaa atttataatt catcttttaa
     6721 aaagaatatg tcttaaaatt agcttttttc taatcaaaat tatataaagc atactttaca
     6781 aattttaaac tcaacttatt tctatttttt acaaaaaagg agatgattca aattttcatt
     6841 ttgaaacatc cccttttgta aatttcttta aaatttatat attaattata ttttcaacca
     6901 ataattgtat tttcaaccaa tctttcttca tagcatttta aatcattttg ctttagataa
     6961 ttaaattcag actctacata aataccacag cctaccaatt caattgtcaa attaggtata
     7021 ttttccttca gtatactagt ctgctcataa ataattcttt ccaataaatc aacttgtaat
     7081 atagaaaaat gcttcataat ctccccatca ctatctatat ctttcttgat ttcataccaa
     7141 ctctttgaca aaattccctt caaatcaata taccctagac tcttcaatat atctatacta
     7201 tcgctccatg catacttact aggtttatca aagtatgatt ctagtttctt cttctgctca
     7261 tttgtaagtg aatcataaga aagcttctta ttaaaatgtg ccttcaaaga aatcttagcc
     7321 atagaatatg gacttctacc agagtttaat cctgcatttt tgaacttttc aattccttta
     7381 tcttctactg aagaccatat tgagtttatt gaatctgaat cattgtattt aatatcaaga
     7441 ccatgtgtaa tatttatata gttttgtgga aatacatatt gataatagac atctttttta
     7501 tcatcatata gagagaagta tccactatca tataaatgaa tatgtacctt tacttttaaa
     7561 ctatcctcta aaatatttcg tctaagattc gggatatttg catacatggt tacatatttt
     7621 atggcatcaa agtttttatt taatggaact tcaaaactaa tttcatctcc tgtcaaaagc
     7681 tttttcactt cttcttcatt acaatcatat agagaatatg tattttcaaa tcccacacgt
     7741 gatttcccat ctaaactgcc tgttaatgct accttcaaaa tatggttatc tgttttttgc
     7801 cattggtaag catcttggtc aagaaactct ctaatctgtc tattttgctc tttcgcctga
     7861 tttataacct cgttttcatc ttctgtaatc cctacatggc atctatttaa gatatttact
     7921 atattgcttc caaatgggaa tgtccatagt tgaaaagctg ctgcctcaac ctgacacaaa
     7981 tatctaacct gatttaattc aatttgatgg ataagttttt tctgatattc attcatctga
     8041 ttaccactat ctgacatttg ataaatcaat tctcccattg caagattatc ttttttctta
     8101 tcaatcttat cagtaatgat aatttgagtt tccatcatat cctgtacttt tttaaatatt
     8161 atagaaatct cctctgaatt ttccattttt aagcttccaa acttcgtgct taattcagtt
     8221 aaaacttcct tcatctttaa tttacttatc tcattttcaa aaatatcttg atttttaact
     8281 gtactatcga atttttctac aaatggtata acagattctt tcaaagtttt atctttaaat
     8341 tccaccattt gagtattcaa ttcatctaat ttcttaatat tattttcttt atctttaatt
     8401 gcctctttaa ctacctctat tttactctca aaactagatt ttacattaag acaattatta
     8461 acaccactaa tcgcagtatt tataagagaa caagcagaac ttccaatact caatgcattt
     8521 ttaattttag atgtcttttg ctgtctttca atagcttgtt tacttttctc tagtgcagct
     8581 aacttatctt tttgctgttt attattgtaa tttgcctcca acatacctat ttcttttttc
     8641 tggatttttg tgtaaatttc cttatactcg ctttcactta acccctcttt tgctctttga
     8701 atatcgtcag ctttgtctgc ataattatca tcatctatag acttaactat aatctcctta
     8761 atttggtcaa atttagttct tctttcttca tcaacacctg ccaaattata agtcatttta
     8821 tctaaagcat tttttctatc ttcacttagc tgttctccaa gtacaaatct cataccatca
     8881 gaatccaatt taaaatctga aaaatcaacc atcctgttgg tccattggta ttcctcttct
     8941 ttagctgaaa gattttcctt caaagatttt gcactgtcaa atgcccctag acaagcttga
     9001 ccaacaccac taaatgcagt cagtaaactc aatgcgcttt gtattccaga aagaattaac
     9061 tgtgttttca tttgttcctc aagttttgcc tgtttctttt ttagttcctc tatgtcttct
     9121 tgttcatctt ctttcatctt tataatttct tgaatcaaca ggttcatttt tgcattaaca
     9181 gaaagcattt tattctcaag ttcatttttt aaaacctcta tttgttgatt tccagattca
     9241 atttgagtta ggatactttc cttatatgta ttgaaatatc cttcttttaa ctcatctttc
     9301 tttccttgtt ccaattctct taaggtctta tccagatagt ctgtcaaaga acgaatatct
     9361 gtaacacgat ttcctccaat ttcactttct tcaatcatct gcacataaaa tgctgtcttc
     9421 tgctcaagtg caaataaaat catactccat tcgctaaaat tctgattttt tcctacaaaa
     9481 gattctattc tatcagactg catcaattta tttataaggt attcatagat ttcctttgcc
     9541 tctttataaa attctttctt tatattcatg tcatccatag aaagtactgc tttatttttc
     9601 ttctcaaaac tatagtactt ctgaagtatt tctctattta attgcatctc tattttctca
     9661 actgcataaa aaatttcata aatatgtgaa aattctaaaa tatcagcttc taaaattcct
     9721 actgcacaca acagtctaag atttctataa cctttaattc cagaaaaacc aaatctctcg
     9781 aaaaattcat agaagaatgt atctattgac aaagaatact cctgctttaa caattccttt
     9841 tcttttagtg catctccaga gtgaccgtct tttccctctg ctccggctga acctgaatct
     9901 tcacgtttgc taattgtcca gtccttatgt tcttcataaa gagtatttaa tttctctcca
     9961 tcatctgctg cttgcttctg atttaaagca tgattaaaca catatctatc aaaataatag
    10021 tagtttctat cactatcatc cattggagga gaggtaccta tatatcttat tgtttcttca
    10081 tatatacctc taattccacc aagacctcct gcaccaccag ctcctccaga gcctcctttt
    10141 cctgctaaac catgatttcc atctttttta cttatagcac tttttaataa aggagctttt
    10201 ccaaggagat aaacctgtcc agacttgctt ccaagacctg catttccacc attacctcct
    10261 gtgcctccag ttccaccttg ttttcctttt tctgctttta ccacatagta ttttgtacct
    10321 ttaacattag caaattcttt tgactctttt ttagaaccta ttttagcatt tgccccagct
    10381 tctccagtta tccctgtatc tccttttttt ccatcttgtc catttccacc acgtccacca
    10441 tctacgtaaa gtttaagttc tcctcttttt tctatttctt taaaagataa tatgatatca
    10501 cctgaagtac ctgcattatt tccatttctt ccattcattc cgtcgtaaat agaactttct
    10561 ccaaccaatt tttctgcatc cttaccagat acgttgattg aataagttcc ttctggtata
    10621 tgtaattttt ctgtaagtag tacaatattc ttacctgaga agacttcttt ctccatatta
    10681 cagtcaattt tcaactcaca atctccatac atatatatag atgacaaaat attaagttga
    10741 taaccagata ttattttagt caaatccgat aaattcactt taggtatagg aatatatata
    10801 gaaagtacat tttctttctc atatgatttt atatatgtac aactttgaat cttctctatc
    10861 ctatactctg catcttcaag ccttttggct tcttcttccc tatattcttc ttctgctatc
    10921 caatatttga tatcttttaa tgtatcttct aaagtatttt ttagcaatga ttttaacaac
    10981 tcacttagac caacaatatg agtctcacta cagtaactat ttaactctaa aagaagacgt
    11041 gtttcttcta atatattcac tttctgtacg ccatcaccat atgaaagttc ttgtacaaac
    11101 tccataagct ctttcatatt attagtccta ctacataaat ctgtatacat cttatctaat
    11161 tgaatctttt tatcttttag actatttata gaagatagaa tggaaataga atcttccata
    11221 ccttttttaa cactttctat ataaggaact aaaagttttt ctaggtcttt ataggttaca
    11281 tcaacagctt tttgtatttc tattttacaa gaagcagtaa gcatcaaccc caaatctgtt
    11341 ttttcaaatg tttcaggtag atttttcatt tcatccaaca acttttctgg ctgtttatct
    11401 agtggattac ataatttaat agatacacca tctgataatg ctacatttaa taagtacact
    11461 aattccttac aaccgtcgta atctttctct tgactatcta ggtcttcttt tgctttttcc
    11521 aatatatttc ttattttttc ttctgttaca ttaccgatta gtgttttagg tattttattg
    11581 ataagaaaga agaaattttc tttatacttt gcataatcac caagcatatc tttcaaattt
    11641 ttgcctgttt ctatcaataa tgtatgtcta gagtccagta gggattgata gtctaaaata
    11701 actaccatcc ctttcacctt tgaagatgtg gaaatagttt cccttacaag catagcacca
    11761 gcaatcatat actctgctcc acggttatca aaaaaacctg ggcaatcaca taatgaaaaa
    11821 tctctatttg caatatctac aacttctgga cataaagtct tagaatatac accatttcca
    11881 atttcgacag ctgaatcttt tgcagttata tatatttgtc cagtctcttc atccgttttt
    11941 tcttccatca cacaaccttt taaataattt atacaagtac tctttccaac gcctgaagca
    12001 cctaagaata acaaaattga cttttctttt aagtcatatt ttctaagctc gtctcttcct
    12061 tcttccaaaa ggtttacgat ttcactataa agtttatttg ccatacatcc atccctttct
    12121 atatttcgga acaatagcct tgatattttt ctttaataag attctcttct acctttgaaa
    12181 cagctgttga taacttagtg tttggagcat taaatcctcc attgtctcct ctatctccat
    12241 attcagcgta ttctcttgct ggtcctgttt taccttcatt ccagcttcca ccactaaatt
    12301 ctatatgata tttaattata ctatctaact tataatccca acttgtaaaa tatcctgtat
    12361 agtatacagt cttatctata ccacttggag aaaatgaaag tgtattatat ccgtgatagc
    12421 caccacttcc tccatatcca cctaaacctg gtctaccatt tggacctgct tctccatctt
    12481 tcactgttat atcacaatga ttaattattc tatttttttg ttcctctgaa tctgaaatga
    12541 agtaaatatt acctttctta ccagcatttc cacctcttcc agcatttcca ccagctccac
    12601 ctttttcacc ttttttgcca cttgtacctt ttgcaaaata ccctttaaac atctgtccgt
    12661 ggaaataact tgtatatcct gcatcagctc cattacttcc agaagctcct gtttcaccat
    12721 ttttcccatc tattccttta gaaccatttc ctccatttgc aatcagtgtt agacgataat
    12781 ttctaatttc ttctttaata tataagtaaa tattacctgc atctctacca tcttcaccat
    12841 ttttcccata catagaatta tctacaagtt ctccgctctt tccacttaca ttaattttta
    12901 cattactacc tacatcaaga ttgttagaag caagaataat atttttctct gatgcaaagt
    12961 ccattccaag gttatcatcc atataaatag tatctttagc aaagaacata aatgtagaaa
    13021 cattgtcatc tacttttcta tttttgaaat attccaatac actgctaatt actaagtttg
    13081 gaattaatgc tcttatttca atacctttct tatcattaat attaattgtt tttactataa
    13141 atggatttaa aatgtattta ccaataaatt ctctaattat ctcattacct tcttctccat
    13201 atgcacttaa tcttgttata ctgtcttcta actcttcatt ttgtgtaact gtaacatttg
    13261 tcaaaattga attaaaatca cttacactat atacataatc ctttttattt gcaacttcca
    13321 ttaatttttc tctatttggt aatgtaaata cctgtttttg cacttcataa gaaactaaaa
    13381 ctttttctaa attctttctt attataatga agttttgttc cattatcttc ttacttgcct
    13441 tttctataat aaattccata tgtacagaag gtaataaaat ttccccagtt ccatgttctg
    13501 tatatttact taaagcatca attatatcta agtttccttt tatcttattt tgtaatttca
    13561 tgcaactatc ttgtaagaat aagccacttt gtttggctaa tacgttgata aatctctcta
    13621 tagtaagact tgttgtactt tccaaccagt ttttaaatac ttttacaacc tcatcatatt
    13681 ttgctatttc ttgaatcatt gttatacttc caataatatt gataaaatct tctgtatacg
    13741 ccttaacata atcttctagg ctagatacga tattgttttg aatttctttt atcaacgtat
    13801 ctaaaactaa tcttgcatct gcactaattg gatattggaa tgctgatgtc ttatctttaa
    13861 cttcatctag ttctagtact tgctttaata agccttccct ctcatctgat gcaagtggct
    13921 tacaaagatg aatatttttt ccattatctt ttagcaattc ttcaaataac caagcttttt
    13981 cctccatatt actgtctaaa ttttcgcata attgttcata ttttcttttt ataacattat
    14041 atatttgttt ttctgttctt cctaagaaac tttttgaaat gaaaaaagtt atactaccct
    14101 taaaattttc tttatgaaga cacatattta actgttggaa caggtctagt acttttgtaa
    14161 gtctagaatc taatatatct gcttctggta tcaatacaat tactgcacat atagatgcag
    14221 aatttttaaa tacttcacct aatgaaactg ctgcactaat atcatgggct actcccctat
    14281 tgtcgctaaa acctgcagta tcacataatt ttgcatccat tccttctatt ggttttctca
    14341 tatttacaat gttcgggtat aaagtttgag aaacagctcc tgaaccaatc tctgccacag
    14401 ggtctaagca atcaatatat gatataccag tatcttcatc ttctacttcc atcattacac
    14461 atcctgcaag atagttaatt gcagtacttt tgccacatcc tgtcccacca agaattagaa
    14521 ttaaattttg attttcagcc ttatttattg ctacttttcc ttcatttaat aagagtgtta
    14581 tttcttctaa aagttgattg ttattttctg gcatttattt tcccccttag ttatatattt
    14641 tatttaaata aagtttaatc ccttaagtag attacaaagt ttttagacta tatttaaatt
    14701 tgttttttat tttttatttt taataaattt gcattttcac taaatttgca ttttcactaa
    14761 ataattattc ttctttgttt attaaaataa ctgtgttgta taatataatc tttatcaaca
    14821 cagttatttt atttaatgcg cttattttat tgtattttat gtaatacagt tgttttttat
    14881 attatatgtc cattattttc ctatggttat tacatataga tttttaatta tatttgtacc
    14941 attaatttaa acattcctat actactgctt aagttttaca cctataccag cttgaatatt
    15001 ttatttttat ttgcttaaat agttcaacta tactggttta aataggttat ctttatttgc
    15061 ttaaatagtt caactatact ggtttaaata ggttatcttt atttgcttaa atagttcaac
    15121 tatactggtt aaataggtta tctttatttg cttaaatagt tcaactatac tgatttaaat
    15181 aggttatctt tatttgctta aataagttca actatactga tttaaatagg tttcctttag
    15241 tttaaataat tcacctatac ctacttgaat agttcacttt tatttgctta aattctatac
    15301 caatactggc ttaaacatta tactaccatg attgtattgt ctatcttcaa ctacaataaa
    15361 aacaggttct aaatctttag tagatgttat ttttaattct aaaaaaacat tatcagttgg
    15421 taatattttt acatcataat tatttaaatt attattcgtg atactattaa atacatcacc
    15481 ttgacgttca aaaaaaacat tatcaactat tacaaaataa acatcttctt ttctactatt
    15541 ttcaacctct atagtatttt gtttagttac atttagtctc atctttcacc tcctattaat
    15601 attacttaat tatattaata cttgtaattg ttgcattatg ttcatcacaa ggaagaggtt
    15661 taaaaacaac tatctctgct aaataattct gtggaggatt tgtaactgaa gtagcattgc
    15721 aaataaattt aaaatttgtt cctgctacaa cttgagtaga aacaataagt ggttcataac
    15781 caaccccttc taacattcct acagcttcat taaatacttt taaatcttcg tcttcgacag
    15841 ctctgaattt tgaccatcca ccagcaaaaa gactcatata aaagcctcct ttatatatat
    15901 ttttatttat atagtagtac caattttctc aatattcaat attttctgtg taactggtca
    15961 atgaaaatga ataactggat aaaaatactt ataaaataac ttaactttac atataaatag
    16021 cttactttac atgtaataag attattctac aatatgaaat gcatcttgtt ttgaatatat
    16081 tctaaataca ataatggata ttttcaatta ttatacttag aaaatatcca ttacttaact
    16141 tgttttattt aaaatcacat agagacttta ttattttttt attgcatgaa tagctatttc
    16201 aggtatcata aggtgatata ccccctcctt gaaaccacaa aaaacatgac aaactttacg
    16261 aatcttggct taaaaaacta caggtacatt ccttatttgt ggattggagt agccataaca
    16321 agcaaatttt acaattttta tgatgacaaa aatcaataaa atcgcttagt atataacacg
    16381 aaatactact tgttactatt aagaatagtt agataggaag tatgcattat gccaataaag
    16441 gaatcaataa agaaagttaa aacatcccta caaattaaaa atctgttaca tttttctata
    16501 tttaaacgtt atttacttac aattggagaa ataacaggtt ttccttctcg gtcaagtaaa
    16561 ggcgtaaatc cggctgcatt gccataatag tggaatacat agttcacacc tgtttcttta
    16621 tccacccaaa tctccgttgc atttattttt ccttgtgaat atactttttc aaatctatct
    16681 tttcccattt tataatcctc catatttttg attggtctat accttcttca cttaagtaga
    16741 aaaaatacat aacttatttt tttaattcta atatgagcac gtaaaaatgt caaacagctt
    16801 atttaatttc ataacttcat gttactgttc gtaaccttgt ttgtttactt acactacatc
    16861 acagcaccat tttacccttt acatgattgt attgcacaca gcaaaaatgc ttactttatt
    16921 ggatttttca actaaaaaaa ggattttttc tccacagaac atttactatt ttttataata
    16981 tatctaattt tactctcata tcaacattta atgaagatat aacctttttc aaatattgta
    17041 aagactcctt aaaaatatta gaaaaagatt ctgcaaatct ctcaacatct ccttttttta
    17101 aatacctaag tatctcaaaa catacatcaa aacgtgtttt caaaatttca ttatattctt
    17161 catgaaaaaa tctctctaaa tagattccaa atatcatata ttgttttaaa tgcaaaaatg
    17221 tttcctgtaa tacataaatt tgtgtataat ctactatctt acaaagtaaa acaaaatctg
    17281 gataaacctt acactcttca caattatttt gtaagtacct taaatgagtt tctattttat
    17341 ctacagctat caaatccatt ttatttccta gtaaaagtac tacatcctca agagtaatcg
    17401 taacaaactc catagcatcc aaaagcaaac tcaacctttt agctccttct tctgtattta
    17461 tataatcatc atcatattca gaaaaaagcg ttacatatgt tcccttgcca ttaattgttt
    17521 tagcaattcc caattcattt agctcattat aggcacttct aactgttgga agagatacat
    17581 tatatctatt aattatcgaa gtaattgatg gtagacaatc tcctatttta atattgcctt
    17641 caaaaatttg acaaattaca tctgaaacaa ttaagtcata taaataacat ttttccaacg
    17701 ttacagaatt aaaactactt gtatctatac tttgtggagc acgattttct accattttaa
    17761 gtatggattc tctacaagct ttatacatat atgttaatag ttttttaaat tcaattagat
    17821 tcccatccaa tccatataag taagtttttc ttacctgctc tatgtattta ttacgaaaaa
    17881 agcctataca acaattatcc aagttatcca agttatcgaa attataggcc aattgtgaaa
    17941 taatgacatc atgctgaata atctcacaaa aatggtgaat caggaaatta tttgttttac
    18001 ttattagttt atttatatat tttagccttt gttctttaaa gactaaataa ttagaactat
    18061 ttttttccat acaatcgata atctcgttta attcttcaaa gtctttagat gtaaatcttt
    18121 taatattgta catagcaata gaaggaaata ttaaactaaa aatcttatat atttctgata
    18181 tttgtaaaat cttctcatat aataagtcag attctattga ttgtttactc gtactctgga
    18241 ttaaaactgg tctagaacca gcttttgtct ctataaagcc cttttctgag agcattttta
    18301 ttacagtttt tatagtattt tttgatacca tatattcttc tgacatgctt tttatagaat
    18361 caagcctatc tccaatagta attttaccag tataaatttg ttgaattata tgctcaaaaa
    18421 taattaaata ttgtggtttt ctcttcatat ttttcctctt cgataaatta gatttattgt
    18481 tttttgtaag gtatatttac ttttatttaa tagggcaaaa tagttgctta ttttttcctc
    18541 ataatctata attaatataa accatttata tatatggtct aagttttata atactgtaat
    18601 gcagtaaaat agcatgttgt agctatacta cagcaaatta acataccatt gtagtatatt
    18661 aattggaata attttaagta cttcaaaatt ccagcaaaac atatatgtgt ttttgatatt
    18721 atgtatattc gttaatagaa tagctatact tgttttacat aataaattat atgatacttg
    18781 ctatatgtaa tcactatatt taatacacat aactattata cttgctatat gtaattacta
    18841 tactttatac acatagttat catatatgct atatgtaatt actatacttt atacacatag
    18901 ttatcatata tactatatat aattactata cttggacaca tagttatcat acatgctata
    18961 tgtaattact acacttggac acataactac tatattt
//
LOCUS       DAEPXW010000074        18734 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.075, whole genome shotgun sequence.
ACCESSION   DAEPXW010000074 DAEPXW010000000
VERSION     DAEPXW010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18734
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.075"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            212..1429
                     /locus_tag="KRM55_002606"
     CDS             212..1429
                     /locus_tag="KRM55_002606"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBH1594829.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1524..1904
                     /locus_tag="KRM55_002607"
     CDS             1524..1904
                     /locus_tag="KRM55_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH1594830.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2188..2670
                     /locus_tag="KRM55_002608"
     CDS             2188..2670
                     /locus_tag="KRM55_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1594831.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSDVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2691..3506
                     /locus_tag="KRM55_002609"
     CDS             2691..3506
                     /locus_tag="KRM55_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1594832.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3559..5109
                     /locus_tag="KRM55_002610"
     CDS             3559..5109
                     /locus_tag="KRM55_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1594833.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5206..6558
                     /locus_tag="KRM55_002611"
     CDS             5206..6558
                     /locus_tag="KRM55_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1594834.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKKRQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6689..7447
                     /locus_tag="KRM55_002612"
     CDS             6689..7447
                     /locus_tag="KRM55_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594835.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDNN
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7494..8213
                     /locus_tag="KRM55_002613"
     CDS             7494..8213
                     /locus_tag="KRM55_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1594836.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8337..9737)
                     /locus_tag="KRM55_002614"
     CDS             complement(8337..9737)
                     /locus_tag="KRM55_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBH1594837.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9741..10649)
                     /locus_tag="KRM55_002615"
     CDS             complement(9741..10649)
                     /locus_tag="KRM55_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1594838.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10910..11557
                     /locus_tag="KRM55_002616"
     CDS             10910..11557
                     /locus_tag="KRM55_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1594839.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11881..14520
                     /locus_tag="KRM55_002617"
     CDS             11881..14520
                     /locus_tag="KRM55_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH1594840.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14578..15681)
                     /locus_tag="KRM55_002618"
     CDS             complement(14578..15681)
                     /locus_tag="KRM55_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBH1594841.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16042..16863
                     /locus_tag="KRM55_002619"
     CDS             16042..16863
                     /locus_tag="KRM55_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1594842.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16942..17153
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17240..18556
                     /gene="argH"
                     /locus_tag="KRM55_002620"
     CDS             17240..18556
                     /gene="argH"
                     /locus_tag="KRM55_002620"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBH1594843.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
BASE COUNT         7165 a         2153 c         3316 g         6100 t
ORIGIN      
        1 agaatgtaaa aaatattttt aaattatcat ttaatgtaat ttaaatgaat tgaagatata
       61 tgtttattgt atgcaattgt tgtattttta ggttttttgt gattaattaa aaaattataa
      121 aaatcgttta catgttgatt tttaaaaaaa aaagatatag aattatatag aaagtaataa
      181 acaaaaattg gatttacggg agtggaatga aatgatgaat gttaccttaa cagatgtgaa
      241 agaggctaga gagaccatta agaacatagt aaaaagaact gacttacttg aaagtgttaa
      301 acttagcgaa aaaacaggag caaatgtgtt ctataaatgt gagaatcttc aaaaaacagg
      361 ttcttttaaa ttaagaggag cttgtaacaa aatagcgagt ttaacagatg aagaaaaggc
      421 aaatggagtt atagcttcaa gtgcagggaa tcatgctcaa ggagttgcat tgggagcaaa
      481 aatgactggt ataaaatcta caatagtaat gccagcaact gcgcctttag caaaagttag
      541 tgcaactaaa ggctatggag cagaagtagt tttaaatggt gcggtttatg atgatgcata
      601 tgcaaaagct gttgaaatac aaaaagaaac aggagcaact ttcttacatc cattcaatga
      661 taagtatgtt atagcaggac aaggaactat atctcttgaa attttcgaac aattagacaa
      721 taaagttgat actatactat gcccagttgg tggaggagga atcatctctg gtgttgctgt
      781 tgcagcaaaa gcattaaatc ctaatgtaaa aatagttggt gttcaaactg caaatatacc
      841 ttcaatgaaa gagtcaataa aaaatggaaa agtaacaaca gcatttaatg atactacaat
      901 agctgatggt atagctgtta aaactccagg agatttaact tttgaaataa taaatgaatt
      961 ggttgatgaa atagtagtgg ttgaagagac agaaattgca gaatcaatat tatttatgat
     1021 ggaaagtcaa aaaatagttt cagaaggtgc tggtgctgta tgtacagctg ctatattaag
     1081 tggtaagtat gtaccagcaa aagatgaaaa tgtagtttgt ataatatctg gtggtaatat
     1141 agacataaat acgttatata gaataatagg tgttgcttta gctaaagaag gaagaagata
     1201 ttcatttagt acaattatgg aagataagcc aggaaacttt gctgagttaa ctagaataat
     1261 aagtgagaat ggtggaaaca ttttaagtgc taatcaaggt aaattatcag caggggaagc
     1321 tctaggaaaa caaagtgcgg aatttatatt agagacaata gattatgacc atatagctag
     1381 aataaagaaa gctatagaag aaaaaggttt taaaattata gaattataat aaaaagtgta
     1441 tataatatac aagaaaaata gtataatagt gtatgaagat acattttatg tgtattagat
     1501 taacgaatta ggaggatttt aaaatgaaac atgaagtaat acatactaat gatgcaccag
     1561 cagctttagg accatattct caagctataa aagctggaaa cttattattt gtatctggac
     1621 aagttcctct tgtaccagag actatggaag tagttgaagg agatgtacaa gctcaaactg
     1681 ctcaatcttt aaaaaatctt aaagctatat tagctgaaag tggagctgat ttttcaaatg
     1741 tagttaagac tacagtattt ataaaagata tgaatgaatt tggggctata aacgaagttt
     1801 atgctgaata ttttggagaa aataaaccag caagagcttg tgtagaagtt gctagattac
     1861 caaaagacgt taaagttgaa atagaagtaa tagctgtatt ataaaaatac aatattttta
     1921 atttgaaaag gctgaaaaac tatattctag tgattcagcc tttttataaa aaaataaatc
     1981 acaataaaga acatgataaa tattgtcgaa ttaaaaaata aaattaaaat aaatattgca
     2041 atatttttga gaaggtttta taatgagtat ataatttgaa acgtgtaact attaaattag
     2101 gcatgagttc ttggatattt ttatcctgag gattcatgcc ttttttgtat tgaaattcaa
     2161 aaatctattt aataaggagg aagtactgtg ttaaattttt tcaagaaaaa taaaagctat
     2221 aagttacatg cagtagtgag tggtaacagc attaatattg agaaagtaaa cgattctgtg
     2281 ttttcaaaaa agttaatggg agatggagtt gcaattattc ctaatagtga tgttgttgta
     2341 gccccttgta atggtaaagt aactgtgctt acagaatcaa agcatgcctt tggtatggtc
     2401 tcagatgagg gtgttgaaat attagtccac ataggaattg atacagttag tttacagggt
     2461 gaggggttta aaaatgaagt gtctcaagga gatactgtta aaaaaggtag tccaataata
     2521 agttttgaaa gagaaaaaat aaattctcag ggaattgatt gtacaacaat aataattgta
     2581 ttaaatcata gcgaattttc agaaataaat tgcatggtag aaaatgaagt tgttgcaggg
     2641 caagatactg ttattgaaat tatgaaataa taggaaggga ttaattcaat atgagagtag
     2701 taaaaatctt taataataat gcattatcta cagtaactaa tgataggaaa gaagctattt
     2761 tactaggtct tggtataggt tttaataaac gtccaggaga taaagttaat gaagataaaa
     2821 tagaaaagat ttattatgtt caagaccaca tgcaaacaaa atttttagaa ttattaaaaa
     2881 atgttagtcc agaagtgatg gatgcttcac aacaaattat aagtcttata ccaggaaatg
     2941 agggaaaatt taataataaa gggatattat ctttagtgga acatattagt tttgcaatag
     3001 atagaatgaa aaataatgtt tttttaccta atttaatgct tttggatata aagatgatgt
     3061 attcaaaaga gtttgaatta ggagtaaaag ctttagaaat tatatataga gtatgtcata
     3121 tccatttgcc tgaagatgaa gcaggttaca tagctttaca ttttgtcaat ttacaatcaa
     3181 atgataattt ggcatatgat actttaaaat ttgtaaaagg tagtattgat ttgattaaag
     3241 aatgttatgg attagaatta gacgaatcga gtttaagtac attacgtttt agaactcatc
     3301 ttaaatttct tgctcaaaga atttttaaga atgaaatttg tcaggatgat aaaatgattg
     3361 aaatgtatga ttatttaatt aacaatcatc ctaaaaataa agaatattta gaaaagttaa
     3421 atgtatatat tgaaaaggag tttaggtata aattagataa acctgaaaaa atttatctac
     3481 tactacacct aacaaaaatc ttataagaat gagatgaatt agtaatagaa atatatataa
     3541 ttttaggggg ggataagatt gaaagaaaaa ctacttggag gactggaaac atttgcaaag
     3601 gcaatggttc agccattaat gtatttatcg agtgcaggaa tattaatggt ggtaggtgta
     3661 ctacttacaa atgatatgtt attaggagta cttccatttt ttaaatggga gccaattcaa
     3721 atatttggaa gcctaattta taactgtata atggctatta ttaataatct tgctgttata
     3781 tttgctatag gtattcctgc tgcactagca aaaaaagaga agcacaaagc agcgttaata
     3841 ggatttatga gttatataat ataccttaca gcttccaaca ctatgttaac atcactaggt
     3901 caactagcaa aagaaagcaa gatgcttgga ctgataggga ctggacaagc tactatttta
     3961 ggtattcaag ttgtagatac aagtgtattt ggtggaatta ttttagggtg tatagctgga
     4021 tatgtattta atcgtacaag caacaaaaca tttaaaggag ctttacagat atactcggga
     4081 gcaaatttta gttttatatg catgttcttt gtatccattt taattggagt tgtgagtaac
     4141 tttatatggc cattagctca acaaggaata gcttctcttg caaatgtcat caaagataca
     4201 ggtacatttg gtttattctt atatggtttt ttagagagaa tattagtacc aactggactt
     4261 catcatttaa tttatacacc atttcagttt tctgatttag gaggagtgct taaagttggt
     4321 gcagatacag tttcaggagc ctatgctata gttatgacag aaatgaattt accagttgag
     4381 cgtttctcag atagtatata ctacatggca actggattta caaagatgtt tggttatata
     4441 ggtataggag ctgcctttat ttatactgca tataagcaaa ataagaagaa ggttaaggca
     4501 acgattattc cactaataat tacggcagta ttagcctctg taacagaacc attagacttt
     4561 atgtttgtat tctgtgcacc acttttattc tttgtacatg cagttatagc tggtcttttt
     4621 atagctttat taaaaatatt tgatgttact gcattatgtg gagggaactt attagtatca
     4681 attataatga atactacagt aggcgtagaa aaaacacact ggccagtaat gatgatatta
     4741 ggacttgcac aaattattgt atattttgta gtatttagtt ttttaattaa gaaatttaat
     4801 tataaaactc caggtcgtga agatgagagt acagctacag gcgaagaaca atcaaaacaa
     4861 cttaatttag atgcagggat agaaaatata attgatgggt taggcggaaa agaaaatatt
     4921 aatacagtag aaaattgcat cactagatta cgtgttaatg taaaagatga aagtaagatt
     4981 aatgaagata taattaattt aacgccaaat agcgggattg taaggaaagg aaaagatata
     5041 caaataattt ttggacttca tgtgcatgag gtaagacgtg cagtagaaga ttttttagaa
     5101 gcttattaaa gatatatatt tatatagcaa gggtaaataa cagctttaag tgctgtttac
     5161 tatttattaa agatacatat aatttataga ggaggaataa ttattatgat tattactatt
     5221 gttggtggag gaagcacatt tactccaggt attgttaagt caattgcatt aagagaaaaa
     5281 gagttagagc ttgaggaaat tcgtttattt gatattgata aaaaacgtca agataaagta
     5341 gctgtagttg tcaactggat actaaaagaa gatgttaaaa cagatgttaa actaactgta
     5401 actaattgtg aaaaagaagc gtatacagat gctacattta tatttgcaca aatgcgtgtt
     5461 ggtaaatatg aaatgcgtga gcaggatgaa aaaattccat tgaaatatgg ttgtgtaggt
     5521 caagaaactt gtggttgtgg agggatggca tacggactgc gtacaataca accaatgata
     5581 aaggttattg atgatgtaga gaaatatgct aaaaaagatt attggatatt aaattactct
     5641 aatcctgctg caatcgtttc tgaagcttgt cgtaagttaa gaccaaatgc aaggattata
     5701 aatatctgtg atatgccaat agctattata gatatgatag cggggtcatt aaatatcaat
     5761 gacgttcata atatacgcta tgattatttt ggtctaaatc attttggctg gtttacttca
     5821 atagattata aacatagaga cttaatggaa gagattaagg aatacataaa agaaaataaa
     5881 atattattac caaaatctta tatagaaaac ttaaataaaa gtcgtagtac aggaaatcgc
     5941 catgctgtaa gtagctggat acatgtttgg gaatctgttt atacaatgtt agaaagcttc
     6001 ccaaaatatc tgccaaacac ttatttaaca tactatcttt taagtaaaga aacagtggaa
     6061 cattcaaaca taaatcgtac tcgtgcaaat gaggttatgg aaagccgtga aaaagactta
     6121 tttgaaggtg tgagacatta cttagaaact ggagaaattt ctgaaaaagc attttatgca
     6181 ggttcacatg gagattggat tagtgatttg gcagtttcaa ttaaaaatga tacacgtagt
     6241 cgttttttag ttataactga aaatcgtgga gctataccaa acatgccata tgatgcaatg
     6301 gtagaaattc cagcatatat tggtaaagat ggtccagaag ttattgctcg aggtccaata
     6361 cctctatttc aacaaggatt aatgatgcaa caacttaaca gtgaaaaatt gatagtagaa
     6421 gcttatatag aaaatagtta tgaaaaagct ttacaagcat tcacattaaa taaaactatt
     6481 ccaagtatga atgttgctaa agaaattttg gatgaaatga tagaagttaa taaggaatac
     6541 tggccagaat taagatagta ggataaaaga aagggttttt atttaatcat tagatatgtt
     6601 ttcagagtct tttatcaaaa tgtattcaca aacatatggc aatatattaa aataaagagt
     6661 gatattttta gaagaatggg gtgatgcaat gaacattata aataaaattt tttggcaaga
     6721 agataggatt ggcatgatta caaataattt agaggcagat acacatagtc actgtatgtt
     6781 acaactgttc ttagggatag aagacagcat tgaaataaca gttaatgaaa aattagttaa
     6841 atgtaattgt atcatagtag ataaaaatat ctctcattca ttttcagcaa gaaaaaaagt
     6901 ttattactct gctattattg aacctacatc tatatatgca gaacagctta cctcaaaaat
     6961 gaatgatttt ggctactgga tatgtgacaa taatggatta gagaaattac gtcaacaagg
     7021 aacttttttg atagataact ctagtaaaga acaatattta agatttatgg aaatgcttaa
     7081 taactatttg aatataccta taactctaaa acattatgat gacagaatta ctgaattgct
     7141 caatttatta cgtacttgta attgtgataa tcatactatt tcaagttttg cagataaagt
     7201 gtctctatca gcaagtagat tatcacatct gtttaaagaa caaataggga tacctttaaa
     7261 aagctatatc ttatttcatc aaatggagtg tgcttttaga gaattacttt ctggaaaaaa
     7321 tgttaccgaa gcttctatga ctgctggatt cgatactcca tcacactttg cagggacagt
     7381 taagcgaatg atgggaatgc ctgtttcttt atctttgaaa gatagcgagt ttttgaaagt
     7441 atattaaata ttctcgttat ataatgaagt tgtactaaga aaggggcttt gttatgaata
     7501 aagaatattt agaagaaaca aaaatgttaa attataatga accacaactt aagcttttgg
     7561 tatcatcaaa gaattggttg gaattagatg attttcataa aataaaatct atttatgagt
     7621 ttgtacagaa tgatatttta tttggatata atgcttctga tatgttaagc gcaacacagg
     7681 tattaaatga tggtatggga caatgcaata caaaagctac tcttttaatg gcattattac
     7741 gtgcagtgaa tatcccttgt aggcttcatg cttttgatgt aacaaaagat tttcaacgag
     7801 gagctacatc caaattgatt tcactattag caccaaaata tattcttcat acttgggtag
     7861 aggtatttta tcaagatagg tggattgctc tggagggtgt cataactgat aaaaaatatt
     7921 tagaagcaat tcagaagaaa ttttttaatc atggtggaac gtttaaaaag tatgcaatag
     7981 ctacaaatga tttgaaaaat acatctattg attgggatgg taaagatact tttatccaaa
     8041 aagaagctat cgtgtatgat tatggtattt ttccatcacc agacgtattt ttttctactc
     8101 attcacaaca tatgtcaaaa ttaaaaaatt tcatatatgt acatcttatc agaaaaataa
     8161 tgacaaaaaa tgtatgtaag gctagaaaca attatattga taaaaatgaa tgagtgttta
     8221 agaggtaact atataggaaa tatatagaat aattaaaact gtactggtta aaatgaataa
     8281 aaaggagtta tcacagagca aacttaaatt gttcatagga taactccttt tctgtattaa
     8341 cttctaataa tttgatgtct ttttataaaa catatagata caattaaacc agtaaatgca
     8401 agagtagctg ctattgaaaa tgcaacatct attccatgaa tgttagacag catgtttgaa
     8461 ctcatatgag ctttcttagt agcacttgtc attatagtaa taagtatagc agaacctata
     8521 gctccagata tctgacggag tgtgttatta attgctgtgg catgagatat aagttctcta
     8581 tctaatgttt taattcccca tgtagttaat ggcattaaaa ccattgaaat accaatcata
     8641 cgaatacaat acatcaatga cacatgaatt aaagatgtat ctctgcctaa aaaagcgaag
     8701 gataaagttc ctaaaaacaa acatcctgtt cctaatattg atagagcatg aggtccatat
     8761 ttatctaaat gacgtcctgc aattggattg agtacaacca tcaatatagc accaggtaac
     8821 attaatgaac ctgaagataa tgcagaaaat cctcttacag attgaacgta cagaggaatc
     8881 attaatgtag cagacatcat tgaggcatat acaatcataa ttaatattgt agaaataaga
     8941 aatggtttat ttttaaaaac cctcaattct aaaaaaggtt ctttagattt taattgacgc
     9001 aatgtaaata aaattaatga cataattcct attaatattg gtaaatatgt ggcaatatta
     9061 gtccacccat aattaccttg attagtaaat ccaattaata aaccaccaaa acctagagat
     9121 gatagtacta ttgaaggtat atctaatttt agtttttgag tttccccaac atttcttaat
     9181 agaataaatg atagtataac atctaatata gcaatagggg aaagaaacag aaataaacta
     9241 tgccaaccaa atgaatctac taaccatcct gataaagttg gacctattgc tggagcaaat
     9301 cctactgtaa taccaactaa actcatagct gcaccacgtt tttcctcagg gcataaatag
     9361 agtataataa cttgtaaaag tggcattaga gaaccagaac ccattgcctg caacacacga
     9421 gcaatcaaca tagttgaaaa attattagaa aaaagtgcaa taatacatcc tatagaaaag
     9481 atagacattg atgtaataaa taactttcta gtactaaatc gatttattaa ataagctgtt
     9541 gtgggtacaa taatacctgc aataagtaga taaattgttg ttaaccactg accaacatca
     9601 gcagtaattt taaaatctga cattatatta ggtaatgctg ttgacaatag tgtttgactg
     9661 agagaactta taaaagcacc agtcattaca attgctatta ttaaatttcc ttttttattg
     9721 ttactttggg tttccataat ttataacgtc tcctttttta attgattttt aatgctgttc
     9781 aataaaagta cttttggtct taaagtgtct tctttttcta aatatgcaat cattgcatcc
     9841 ataattaaag aatcatattg ttgatttttt ccctcgacgt ataatttttt tattgcttct
     9901 agtaatttag gattttcaag gagagaagta tcagttttga ttagttcttc tatatcttgt
     9961 atcgttttaa aaaatagcga tttattatga agggaaaagt aaacttcatc ttcttgttta
    10021 tgtaaaaaca ttgatttttc aattaaagga tttagattat ccatattttc tacaactaaa
    10081 tctagaattt gtatagtaaa tttggcaata aagtatacat ttatttctct tttttgtaca
    10141 tgaataatgt atataaactg atgaattaga gcatccaata agaaaactaa atcaaatata
    10201 attttttcta ttttatcacc atagttatca aataagctta atttgtattc attcaataag
    10261 ttagctcgtg attttgtttg caatttactt gtagccttac gttgctcttc agaaaagttt
    10321 tctcttatat aggtatttat ggtagttcta gaaaaaatat ttttccatac agcaattatc
    10381 tttctgttta acttttctga tgatggaatg tcattatttt cgtttatgga atgtataatt
    10441 tctaaaaact tttcatcata ataattgatt atttcgcaga taaaactttc cttagtttca
    10501 aaatgcttgt aaaaagtagc tttagacatt ttacactctt ttacaacatc cgatattgaa
    10561 gtattttgaa aacccttttg gtcaaaaatt ttttgtgcaa tagttataat gagcctttgt
    10621 ttttctgtca ctttattatc tcctttcacg caaaaacgtt tagtactata tagtacctac
    10681 aagttttaat aaatatatta tacatcattt ggaaaaaaaa tcaatatata gactgtaata
    10741 tgaaattttt gaaaaatttg ttgttatttt tagtcgtata aaaaagaaac ttaagagttt
    10801 cttaagaatt gtttaaagaa gttgcaataa attagtggta tgattatagt atgaaagaga
    10861 atgtcttgaa atttttctgt atcaaattcc aattatggag gtgtagtata tgaaaaagaa
    10921 aatttgtgta gcaataattt ttgctctatt tatagttttt gtagaaatgt ttattgatag
    10981 ctctagcgaa ggaagtaaaa ttatgacagc tgaattaagt aaatacagga aaggcgtaaa
    11041 tgtattatca ataaacaata ttatagtagc gaataaaaaa tatagtttgc ccaaagatta
    11101 ttctcctcag gaaagcagtg aagcgagaga tgctttttat aaaatgaata aagatgctca
    11161 aaagtcagga ttaaatttaa aagcttttag tacatataga agttatgaat atcaagatag
    11221 attatttaag tcatatgtaa aagaacatgg agaaaaagaa gcaaatagat tttcagctaa
    11281 acctggagag agtgagcatc aaactggact tgcttttgat attggaggag atgaccagtc
    11341 ttgttgggca aataaaaagt tcaacaatac aaaagaagct aagtggttgt atgaaaatgc
    11401 atataaatat ggttttatac ttagatatcc agaaggtaaa gagaatataa caggatatat
    11461 gtatgaatct tggcactata gatatgttgg aactgaacat agcaaaaact ttgcaatgaa
    11521 taatttgact ttagaagaat atttacatat aaattaagag atggtttgtt aaaattaggt
    11581 taaaataaaa aataacctag actattagct gtgtaaagtg atataatgta aatacaattt
    11641 agataactac tcgaagggga gtagcttaca cgaaagtggt aattaatcgt caagacagta
    11701 gaaatactcg gttaattagc aagggattcc ttgatagcaa gaccttcaaa ataagcatta
    11761 ggtatgtttg ttttggggtc tttttttatt caaggaattt ttatttaaaa aaatttaaat
    11821 ttcaagtata cataagagcc cccaaacata aaataaattt attgaagagg agggcaacaa
    11881 atgtcttaca aaagtactta tcaagaagta attaaaaatt tagactcaag tttatctggt
    11941 ttgagtaaag aaagagcaga agagttgtta gaaaaaaatg gagctaatga attaaaagaa
    12001 gcagataagg ttcctactta taagcttttc ctagaaagtt ttaaagaccc attagtaata
    12061 attctattga tagctgcttt agtacaaata tttttaggtg aaacagtgga gtctataata
    12121 atttttgcag ttattattat aaactctgtt ctgggtgttg tacaaacaaa aaaagcagaa
    12181 agttcattag aaagtttgaa aaatttatct gcaccaaacg caaaggtaat aagagacaat
    12241 aaaaaaatga caattccagc aaaaaatcta gtagttggag atattgtatt cttagaagct
    12301 ggcgattaca taccagcaga tggaaggctt atagaagcac aatctctcaa ggttgtagaa
    12361 gggatgttaa ctggagaatc agaaccagtt ttaaagcata cagaaaaaat aagtgaagat
    12421 gtaagtttag gtgaccagaa aaatatggta tttagtggtg ctgtagttgt ttatggtaga
    12481 ggttcttttg tagtgactgg aacaggtatg gatactgaga tgggtaaaat agctgggctt
    12541 ttagaaagtg ctgaaaataa acttacacca ttgcaacaaa aaatagagga ttttagtaaa
    12601 aaacttggtg taggtattgt aatacttgct cttttaatat ttataattca agtagcaaga
    12661 aattacttta tggctggaaa tggagaaatg acacaaatta ttttagattc attcatgttc
    12721 tctgtagcag tagcagtagc agctatacca gaagctctat catcaatagt cactatagta
    12781 ttggctgttg gaacaaatag tatggcaaaa aaacaagcca taataagaaa attaccagca
    12841 gtagaaactt taggttcaac aagtgtaata tgtactgata aaacaggtac tcttacacaa
    12901 aataaaatga cagtagttga ttattatatg tatggaacta ataatgatga gttagataaa
    12961 gaaaaagtaa actattctta tcatgctaaa ttattgacta tggtttctac attgtgtaat
    13021 gactctcata taactagtga tggtaaagaa gttggtgacc caacagaagt ggctttaata
    13081 aattattcaa gtaaaaatga tttagattat gataaattaa gaagtaagta tatcagaata
    13141 aatgaaatac catttgactc agacagaaag cttatgtcta ctgtaaatag tatatatgga
    13201 gattatataa tgtttacaaa aggtgctcca gatattgtgt ttagtaggtg taaatatgct
    13261 ttgaaaaatg gttcaaaagt agatataaca gatgagataa tagaagaata taaacataaa
    13321 aatgaagagt tttcaaatag agcacttaga gtattagctt ttgcaataaa agatgtccca
    13381 gaagaagatt ttataccttc aattgatgac gaacatgaca tgacattggt tggaataatg
    13441 gcaatgatag acccaccaag agaagaagta atggatgcag taaaagaggc aaagagtgct
    13501 ggtataaaaa ctgttatgat aactggtgac cataaaacaa cagcagcagc aattgcaaaa
    13561 gagattggta taatggaaga aggagacttg gctcttactg gaaaagagct tgatgctttg
    13621 agtgaagaac aactatatga aaaactagaa aatataagtg tatatgccag agtctcgcca
    13681 gaaaataaaa ttcgtatagt aaaagcatgg caacataaga ataatataac agcaatgact
    13741 ggtgatggtg ttaatgatgc acctgcatta aaacaagcag atataggaat cggtatggga
    13801 agtggtactg atgtagcaaa agatgcttct gctatggtat tggttgatga taactttgca
    13861 agtatagtaa atgctgttga agttggtaga acagtataca gtaatataat aaaatcaatt
    13921 acttatctat ttgcaggaaa cttaggagct atagtatcca tagtatttgc agtgtttgca
    13981 ggttggtcaa atccatttac agctttacaa cttttgttta taaacttagt aaatgactct
    14041 ttaccagcaa ttgcattagg gtttgaaaag tcagaaaaaa atataatgaa taaacctcct
    14101 agacacccgg atgaaagtat actagcagga ggaacattga aggcagttgc tataagaggt
    14161 tgtataatag gtgtagttac aataattgca caatatatag gattacaagt atctccagaa
    14221 cttggagtag caatggcatt ttcaacattg atattagcta gaataatgca aacattacct
    14281 gcacgttcta ataatcaaac agtaataaaa ttaggttttt tcagcaataa atacgttata
    14341 ggagcagttt tagtctgtct tgggctttac tctttaacac taataccagt gctaagagga
    14401 atattctcta taccaacaac gtttggattg taccagttgg ggatttgcct agggttagca
    14461 ttaatttcat caatattaat ggaacttaac aaattaataa atagaagtga agtaaaataa
    14521 tcaaaaaatt aaagggcata ttgattttaa caatatgcct tttataaata gtctaattta
    14581 ttctatatta tcgattattt ggaatgcttt tataacttca ggtaattctt tttcttcagg
    14641 cattctaaat cttatgaaat ttttatcaag tccagtaaaa tcacttccag atataactct
    14701 tatttttaat ttagcaaact cttgttgtaa atctatgtcc ttgtttttat gttcaactgt
    14761 cataattgat acagtatcac tagtttcagc tatattaagg tttttccatg gaattaataa
    14821 ttgatttttt atatcttttg ttttttcttt taattcttct ataaattgaa catcatctaa
    14881 taaatttgct gcaatactac gagatatttc agacacttcg taaggagtag aaatcttttt
    14941 aatagggcta acaagttgtt ctggaagaac tgcatatcct gctcttagtc ctgctaaacc
    15001 aaatcctttt gaaaatgttt ttaaagcaat tacattatca taattattta gaagcttgac
    15061 agctgaattt tcttttggca tgtattcacc ataagcttca tctaccataa ctgctatatc
    15121 atatttagct gcttccttta ctatattttc aattgatgat aaaggtataa tttgtcctgt
    15181 aggattgttt ggattgtcta tgtaaattac tttatattct ggatttattt tttcaataaa
    15241 ttctttttca ttaaacttga aattatcctc tttctttaaa agaacataat cataagttgc
    15301 accatgcatt tttatatctg tctcatattc tgagaactga ggtgaatatc ctaaaacttt
    15361 atctcccttt tcaataaata gtctatttaa aaggtaaata acatgtatag aaccatctgc
    15421 caaacaaatt ctgtcagtat ctaatgctat aaaatctttc caataatcaa ctatattatc
    15481 ttttaaagca attgaatgag gatatcctct tatcatatca aattttaaag cattaaaagc
    15541 ttctacagct ttgtttgagt aagacacggt atttatacct tcaccacagt ctatctcgaa
    15601 tacatcttct gaatgtccag attctattgc ataacttttt ttcaactgca tttcaatagc
    15661 tttgttaatt tttagtttca tactttatca ctccttattt agtcaataat aaatgttata
    15721 aaagttgcta gatttaaaat attatgaaaa tatataatag taaaaaatga atataaatat
    15781 tataatagct cactttattt aatatgatta tatatcatat attgtaaaat ttctagcatt
    15841 ataagactat aaattgaaaa tattcagaaa aatactacaa gaaacgattt attttgctct
    15901 taaaataagt taaatgaatg ttattaattt tgtaaattga aatagtttaa gtataaagtt
    15961 atgatataat ctaataaggg taattcttta gattatatta aggaaatata ggtatacaat
    16021 aaaaagttat ggagttggat tatgggatat aaattaattg taacagatat ggatggaact
    16081 ttattaggca ataatcataa agttacagat gaaaataaaa ctgcactaca aaaagttata
    16141 aaaagcggta ttaatgtaac tttagcaaca ggaagagcct tcgattcagc taaatgcaat
    16201 gtagattttc ttaaagagga catgccaata atagcttgta atggttcatt aataagagag
    16261 caaaatggaa atataatata ttcaaataag attgatacaa gaacatgttt aaacatttta
    16321 gatgtattag ataaatacga tatttactac caatgtaata gtatagattc tatgctttcg
    16381 aaaaaaatag aaggacgtga agatagatta agtgtatttt taggctctga aacagaagta
    16441 attgtaaaag atgatttgag agaagaaatc tttaaaaaag atatactaaa atttgtaatc
    16501 atagaagaaa aaaatccatc tattttggat gaaataagaa aagaattgag aaaagttcaa
    16561 ggaataaaga taacttcttc atggccaaac aatattgaag tcatgaatga aggtgttgat
    16621 aaaggtaatg cagttaaaat tttagctgaa aaaatgaata tagacagaga agatataatt
    16681 gcatttggag acaattacaa tgacatagaa atgataaagt ttgctggtct tggggtagct
    16741 atgggaaatg cagaagaatt gattaaacaa gaggctgatt atgttacaga tacaaatcaa
    16801 gacagtgggg ttgcaaaggc aatttataaa ttcctagagt taaaagaatc acttagctct
    16861 taaaacagta tataatagga aaaaataggt tgactatttt gtagatagta attataatac
    16921 aaatagataa aacataaaaa tttagattca gtgaaaaaga gagtagatat agagaaaatc
    16981 tcagcgaatt gggggatggt gtgagcctaa tgataacact ttatattgaa aagaactttg
    17041 gagaatacta cttgaaattc agtatggtag taggtaatct cgccttaaga gaatagagtg
    17101 ggtaaacatt gtttaccaac tagagtggta acacggaata tttcgtctct tggtcttttt
    17161 gaccaagaga ttttttagtt tcattgagtt acaagactta taattaaaat acaaaaaatt
    17221 aaaatatgag gtgaaagtta tgaaattatg gggcggacgc tttagaaaag cggaaaatca
    17281 acttatggaa gaatttaata aatcttttgg ctatgattgt gtactgtaca aaaaagatat
    17341 cgaaggaagt gtagcacatg ttcatatgca agtaaaatgt ggacttttaa cagaagaaga
    17401 aggaaagtct ataacagaag gtttaaaagg gatacttgaa gatgtagaaa atggaaagtt
    17461 agtattggat ggagagtatg aagatataca tagttttact gagataaatt taattcaaag
    17521 aattggagat gttggcaaga agcttcatac agcacgtagt agaaatgacc aagttgcagt
    17581 tgatatgaga ttgtatgcta aagaaaaagc aaatgatttg gtggatttaa tatctgaatt
    17641 taaagctact ataaaagatg ttgctgacaa aaacccagtg atgatgccag gctatactca
    17701 tcttcaaagg gcacaagtag tgacatttaa gcatcactta atggcatatt atagtatgtt
    17761 tgatagagat gagaaaagaa taaaaaatgc tatagaaata ttagatgaat cacctttagg
    17821 ctgtggagct ttagcaggaa ctacgcatga tatagataga agtataactt gtgaacaatt
    17881 aggatttaaa aaagtagtag ataattttat ggatggagta agtgatagag attatttact
    17941 agagctaatg agtgattttt caattataat gatgcactta agtagattaa gtgaagagtt
    18001 gatactttgg agttctcaag aatttggatt tgttgagata gatgatttat atacaactgg
    18061 aagtagtata atgcctcaga agaaaaatcc agatggtgca gagcttataa gaggtaagac
    18121 tggtagagta tatggaaact tatttggtct ttttacagta atgaaaggaa taccattagc
    18181 atataataaa gacatgcaag aagataaaga aggttttttc gatagtgtac atactcttga
    18241 aatgtgtata caaataatgg atagaatgat agccacacta aaggtaaatg aggataaaat
    18301 gaaacaagca gtaaaaaatg gttttttaaa tgcaacagaa gttgcggatt atttggttaa
    18361 aaataatgtt gcttttagag atgcacatgg tatagtagga agtatcgtta tatattgtga
    18421 agataataaa aaagcaatag aagatttaac attagaagaa ttacataagt tttcagatgc
    18481 ttttaaggaa gatatttatg attttatcga ctatgagagt atattaaata agggaataaa
    18541 aaagaattta aaataatgta tttattttta aaagctgtaa atttgaatgt tatcatttaa
    18601 atttacagct ttttattgtg taagatttta ttatataaaa gtaagaaact taaaaggagt
    18661 agtatttaaa ataaatacaa ataaaaaatt attattaaaa tgataattaa tatcaataag
    18721 tattgacaaa gtta
//
LOCUS       DAEPXW010000075        18669 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.076, whole genome shotgun sequence.
ACCESSION   DAEPXW010000075 DAEPXW010000000
VERSION     DAEPXW010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18669
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.076"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(32..1063)
                     /locus_tag="KRM55_002621"
     CDS             complement(32..1063)
                     /locus_tag="KRM55_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBH1594844.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            1251..2141
                     /locus_tag="KRM55_002622"
     CDS             1251..2141
                     /locus_tag="KRM55_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1594845.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            complement(2193..3119)
                     /locus_tag="KRM55_002623"
     CDS             complement(2193..3119)
                     /locus_tag="KRM55_002623"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBH1594846.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEVDFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDLWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(3334..3918)
                     /locus_tag="KRM55_002624"
     CDS             complement(3334..3918)
                     /locus_tag="KRM55_002624"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBH1594847.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHEIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            complement(4003..4905)
                     /locus_tag="KRM55_002625"
     CDS             complement(4003..4905)
                     /locus_tag="KRM55_002625"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH1594848.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            complement(4898..5590)
                     /locus_tag="KRM55_002626"
     CDS             complement(4898..5590)
                     /locus_tag="KRM55_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBH1594849.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALLGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMAEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            complement(5629..6549)
                     /gene="pyrB"
                     /locus_tag="KRM55_002627"
     CDS             complement(5629..6549)
                     /gene="pyrB"
                     /locus_tag="KRM55_002627"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBH1594850.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKSKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            complement(6845..7867)
                     /locus_tag="KRM55_002628"
     CDS             complement(6845..7867)
                     /locus_tag="KRM55_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1594851.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGEWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            complement(8783..9916)
                     /locus_tag="KRM55_002629"
     CDS             complement(8783..9916)
                     /locus_tag="KRM55_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH1594852.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDGEIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLDVLPKGFEDLRTVSSIRFSVIGF
                     TYADAPKNMREEYKINCESLGLIPKDSDKIEVGIEYYDSLLND"
     gene            complement(10246..10836)
                     /locus_tag="KRM55_002630"
     CDS             complement(10246..10836)
                     /locus_tag="KRM55_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1594853.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFIYIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIKKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFVYADAPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            complement(11049..12314)
                     /gene="gluD"
                     /locus_tag="KRM55_002631"
     CDS             complement(11049..12314)
                     /gene="gluD"
                     /locus_tag="KRM55_002631"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBH1594854.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            complement(12443..13267)
                     /locus_tag="KRM55_002632"
     CDS             complement(12443..13267)
                     /locus_tag="KRM55_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1594855.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVYKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            13540..14727
                     /locus_tag="KRM55_002633"
     CDS             13540..14727
                     /locus_tag="KRM55_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1594856.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            complement(14867..16093)
                     /locus_tag="KRM55_002634"
     CDS             complement(14867..16093)
                     /locus_tag="KRM55_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1594857.1"
                     /translation="MNYVVLGASAASINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDELAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFNIKENGEFCYSI"
     gene            complement(16068..16541)
                     /locus_tag="KRM55_002635"
     CDS             complement(16068..16541)
                     /locus_tag="KRM55_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1594858.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDAEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            complement(16534..18435)
                     /gene="cooS"
                     /locus_tag="KRM55_002636"
     CDS             complement(16534..18435)
                     /gene="cooS"
                     /locus_tag="KRM55_002636"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH1594859.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
BASE COUNT         6090 a         3307 c         1984 g         7288 t
ORIGIN      
        1 tcaaattaat attacaaata ctatttttat gctatataaa tatttttatt aaaactacag
       61 ctgatacaac ttgtactgta cctacaaata aaccatataa agaaacttct ttcccttgtt
      121 tcactaaatc ttttacatta acctttaatc caattgctgc taaagctatt atttctagtt
      181 tgttacttat ttctttgcac aacacagata cttcttgtgg tataatgttc attgaaaaaa
      241 gtgcacaagt tataaagaat ccaattacat accatggtat agtcactttt ttctttttta
      301 tctcatcctt ttcttcttca agaatttccc tattagattg atttttcata tgtccaaata
      361 ctaatacaac aacaactaga aatattactc ttactatctt aaaaatagta gctaaatctt
      421 ttacattttc tccaacaatt gctccacttg ctacaacctg accaattgat tgcaaagttc
      481 cacctatcat tgctgaagtt tttacaagtt catggctata taaaaattga gatattattg
      541 gaagtaaaaa cataagaaat ataccagtaa catttacaat agttactgca attccctttt
      601 ctttatctgt cgcattaacc actggaactg ttgctcctat tgcagaagaa ccacatactg
      661 catttccact tgccattaga aatctaaagt tttcttcaaa tcctagtttt ttacctatat
      721 aaagtgcagc tattattgtt attgtcattt gcaatattat aaataaaatt cctgaaactt
      781 ttaagtctat taaggtagat acactgagtg ttgctcctaa tagtactatt gaatatgata
      841 acaaatctgt ctctgaaaat ttataacctt tttgaaatac cttttgattt aaaaataggt
      901 ttcctacaaa catacctaaa aatatagaaa ttgatgctgc ccctacctta ggaattaaaa
      961 tagaaataaa tatactaata taacctacta atactgatac aaacagtcct ggtaatattt
     1021 cccttatagt ttttaatgtc aaactgcttt ttttctttaa cataatatac ctaccttata
     1081 attaatatag ttttcttcat agcaatagta tataattgta ataaccataa gtaaaataaa
     1141 tatataatat cgtaatgatt aatgttttta atggttatta tatatagtat aattatctgt
     1201 agaaagtata taaaaaatgt aaaatttcat taggtaaagg agacaaaaaa ttgtttgaag
     1261 aattaaaaac atttgtagct gttgttgaat acaaaaactt tactaaagct ggggaatatt
     1321 taaatctatc acaaccaagt gtaagtaaac acataaaaaa tctagaaaat tattttaaag
     1381 ttgtgcttat aaacaggtct attaaacaaa aaaccatttt tataacagaa agtggacaaa
     1441 tcttgtacaa aagagctaaa gaaatattaa atcttttaaa tattacttat catgatgtaa
     1501 gccaagtttc agatgctata actggtcact taaagattgg tgcaagttta actattggag
     1561 agtatatttt accaaatttt ctagcattat tttctaaaaa gtatcctgac atagatgtag
     1621 aagtttttat aaaaaataca tcaatcgtat cttctcatgt taaggattat attttagaca
     1681 ttggtcttat tgaaggcact tgctcttccc cttcatttat tcaagaatat ttttttgaag
     1741 ataagatggt tttagcactt ccatacaaga gtcatttatt aaaagatttt agttttgata
     1801 aacttcaaaa ccaaaaatgg atagtcaggg aggatggttc tggaaccaga gattatttag
     1861 atatgttttt aagtgttaaa gaaattattc caaaaagtat gatggttttt ggaagtaatt
     1921 atgctgtcaa agaatctgtt agaaataatt taggaattac aatagtctct aatctagtga
     1981 caagcttacc tgttctaaac aatgagctgt ctgtcataga gcttggaagc agctacaaca
     2041 gacatttctc atatatattt ccaaaagata taactttatc aaaagcagca actattttca
     2101 ttgaagagtt aaaaatattt agtaacttaa atagtatata acattaataa aatttaaaat
     2161 caataattat caatatttct tacaaagacc ctttaaaatc tactttcaat tacttttatc
     2221 atataaaaga aagtctgatt tataggagta ggtatgttat atttttttcc aagtttgcag
     2281 atattcttag aaaacatatc tacttctgta agtctatgag cttccacatc ttgaagcatt
     2341 gatgttcttc cttcttttga atgttctagt attctatgta atgaatgttc cacatcatct
     2401 tctgtaagag atatgtcttt tgcttgtgct atagcaacaa cttccctcat tgcagatttt
     2461 gctaattctc ttaaatgctc agaactctga aaaactccat aaggtgcacc aagtatagct
     2521 gaagtttgat ttacaccaat attaaccatg tacttccacc acagatctcg ttgaatatct
     2581 tttgataaag tatattctat atttacatca tcaaagactt cggttattat attagttttt
     2641 ctatcttcac tattatcttt gttaccaaat acaattatcc cattagtagt gtgtataata
     2701 ttattattga ttttctttgc atctatattg gtaacatatg aatataccat tttttcaatt
     2761 ccaaatcttt ctcctattat ctcttcgcta tcaactccat ttagcagaga cattataact
     2821 gtattttttc caactaatcc atctaattct tttatatttt cttttaaatt attatatttt
     2881 agacctataa ttataaaatc aacctcttgt ttatactcat ctttagttac ataatcaaaa
     2941 tcataccttt ttccatttat tataaatcct tcttctaaat atcttttctt tctttcatta
     3001 tcacaaagaa ttttaaaatc atatttagag ttaaaaaatt gttctgcaaa agtagctcct
     3061 acagcaccta ctccaaaaaa tacaaccttt ttatgatttt catttaattg atttttcata
     3121 cttacccctc cctaatacat aatactttta ccttatactt atattgtact gctactatct
     3181 cttattttgt aaatatattt ttaacaaaaa aaacagctaa ccttcattta taaggctaac
     3241 tgctttttat ttttaagtta tatgttatat tacaaatttt tactctaaaa aatttacatt
     3301 ttttaagtaa cactataaat aattaagttt ttattacatc cctaattcct tgaactctct
     3361 acttccaggc ttaacaactg gtaattttcc ttccttacat aaaggacact catcagattc
     3421 ataaacttga atatcaagtt ttatagcact atatataggc atacctatct catgattagt
     3481 tctatctgct atacatgcaa cacctacaac ttctccacct aaggcttcta atactctttt
     3541 tgtctccata gttgatttac cagtagttac aacgtcttca gcaattatta tctttgctcc
     3601 ttttttaact tcaaatcctc ttcttaactc cattgtattg tcttttctct cagtaaatac
     3661 agcttctttt cctaattgtc ttcctaactc ataagaaact attactccac ccatagctgg
     3721 tcctactact aagtctatat ctaagtcttt tatttgttca acaactgtac ttaatacctc
     3781 agcagcatat tctggaaatc ttaatacttt tgcacattgt acgtatctat tactgtgttt
     3841 tcctgaagat aataaaaaat gtccctccaa caatgcatca cttttcttta atatatccac
     3901 tacatctact ttactcatat tatttttcct ccatgttaat gttataaaat tatggtttat
     3961 ttaatctata ttttttatct ttaaaatact atttattcta ccttatataa ttcctcttat
     4021 ttcgtctaaa ctttttattc cttctctatc cataaattca ttaattccat ctattatttc
     4081 aatacctatt ctaggattca taaaatttgc agttccaact tggatacaag tagctcctgc
     4141 cattataaac tctatagcat ctgtggcttt agttattccg cccattccca ttacaggtat
     4201 atttacattt ttacacactt catgtaccat tctcaaagct ataggtttta tagctggtcc
     4261 agataaccca gcatatacat tttcaaatac tggtcttcta ttttttatat caattgccat
     4321 tgctttaaaa gtattaacta atgaaactcc atcagcacct tcttcttcac aaacttttgc
     4381 cattcctaca atatcttctg cattgggtga taattttatt actaaaggca gtttcgttat
     4441 gtttcttacc tcacgaacaa cttctcttgc cacttcattt tttataccaa aagccattcc
     4501 accagctttg acatttgggc aagatatatt taattcaata atgtctatag gcttgtcatt
     4561 taacatttga acccctaata agtagtcttc taatgtccca cctccaacat tagctattct
     4621 gactaagtct agtttactaa aaaaaggtaa ttcatagtct ataaatcctt gaactccagg
     4681 gttttcaagc ccaacactat tcatcatacc ggatggtgtc tcatgaactc tcataccatt
     4741 gttaccaggt tttttattta aagtaagacc cttgctactt ataccaccaa gtttttgtat
     4801 atcataaatc tcattatatt cttttccaaa tccaaaagtt ccagacgcca ttattactgg
     4861 atttttaaat tctacacttc caaatttcac acttaaatta cccattaaaa atcacgtcct
     4921 ctccccagaa cactggacca tctttacaag tctttttatt tcctccatta gttttacacg
     4981 tacatactaa acaggcacct actccacaag ccatatggtt ttcaagagat accataattc
     5041 tcgttttagt accttctgcc atcttaacta atttttccat cattggagtt ggaccacatg
     5101 ttaatatata atcatatttc tcaacatcaa ttatatctgt tacaaaagta tttcctactg
     5161 ttgtatagac tttattacat acttgtttat attcatcttc taatataaca tcttctctaa
     5221 acccaagata tgcatcacaa ttttttatat ttttagcaac caaatatagt ggagctacac
     5281 cgattcctcc tcctaataga gctacctttc catcaacctt agcatatcca ttaccataag
     5341 ggccttctaa ttttatatta tcatttacct ttaggttact caaaatttga gttccttctc
     5401 ctactacttt ataaagaaaa gttatccctt cttcatctat atcatgtata cttataggtc
     5461 ttgaaagtac tggataagta tcccatgctc ttaacatata gaattgtccc attttacctt
     5521 caaaattacc ttttactttc attctataca tatcttcgcc tatatatata ttttccagaa
     5581 ttttatacat cccaaaatct cctttgtttt actattatat gataactatt agtcttcatt
     5641 tatacctaaa agttttatta ttaaagccat tctaacatac attccatatt tagcttgttt
     5701 aaaatataca gctctatcat cactatctac atctatgtct atttcattta ctcttggtaa
     5761 tggatgcatt actaacatat ctttagatgc cttttctaat ttagatttat ttaaaatata
     5821 atagttttta agtctttcat actctgattt atcttcaaat ctttcttgtt gaactctagt
     5881 catatataaa acatccaagc ttcctataac atcatccaaa ttattagttt cataatatgc
     5941 atgtcccttt atagcttctt ttatataatc tggcattttt aactcttcag gcgctataaa
     6001 tacaaacttt gtatttttat atcttgccat agccttaacc aaagaatgca cagttcttcc
     6061 atattttaaa tcaccacata atcctattgt atggctttct aaagttcctt ttaatgattt
     6121 tatagtaagt aagtctgtaa gtgtttgagt tggatgctgg tttttgccgt ctcctgcatt
     6181 tataaatggc acttccgtat atctagctgc ttctgaagct gcacctgatt gaggatgtct
     6241 catagctatt atatcaacat aaccagatac tatcctcatt gtatctccta gagtttcacc
     6301 ttttgatgca gaggatgaat ttggctctga aaagcctact acacgtcctc ctaatctgtt
     6361 catagcagat tcaaagctta atcttgttct tgttgatggt tcataaaata atgtagctaa
     6421 tagttttcct tcacatatac gagaatattt tgacggattg tcaattattt tttgagctaa
     6481 ttctaatatt tcatctattt cttctattga aaagtcttct ggttggatta aatttcttga
     6541 ttttaacatc tttcgtcctc cttttttagc ctctctgaac taaaattaaa agtatttttg
     6601 tactgttagt agcttaccac ctttgcccta tcctgtcaag ggattgcgca aataatcatc
     6661 atatgaaaag gctcctattt aacagtcata ttaacttgaa tcttgattag atttaaagtg
     6721 atacaaaaac gctctatagt acatttaaaa tataatcatt ttttgtttcc atgattaaat
     6781 taaatataat atagagcgtt tatatatatt tatgtattta tcaatttgtc atattacaaa
     6841 ccgattataa tattcttttt gctgtaacaa atcttgctgt atagtatgat gaatttatac
     6901 tagttacact aactgttttt cctgttgatg gtgaatgtat catattaccc ccacctacat
     6961 atattccaac atgactaaca gaaccagaac cattagttgt gaagaatact aagtctcctg
     7021 gttgtaaatt tgctttactt acagtttgtc catatttaga ttgtgcttta gatgttcttg
     7081 gtatattctt tcctactgca tttctataca catattgtgt aaatccagaa cagtcaaaag
     7141 tgtttggtcc ttctgctccc caaacatatg gacaaccttg cttagaatat gccaagttaa
     7201 gtacagcttg aactgcatta gagttagctg ttggcacatt tgaattatta ttttgttgat
     7261 tagtatttgc attgttttgt tgattattat ttgtagaatc tacattttgg tcaatacttg
     7321 ggtttacttg tggctcttct attacaggag ctttatcaga tatataagat gattttacat
     7381 atccttctgt ttccccatct ttaactttta accattctcc attatcttcc aaaaccaata
     7441 aagaacttcc tttttccagc tcttcaatta cttctgaact ttcactctta tcttttctta
     7501 agtttacttt atcagcgtta gtatatccta caccttcaga tatatctaca tatctagtag
     7561 ctaaccaacc ttcgccatct tcaactttaa ccttaaccca ttctccttga gttcctaaaa
     7621 ccgtaaattc atctccagaa taagctatgt tttgaacttg accttcttct cttatcttta
     7681 tagctactcc atcttttatt tttgcaactt tatattttac ttctttatat tcacctaaat
     7741 ttaattcagt atttgtttta tcatccttat tttgagatga atcatttact tcatctgcat
     7801 ttacaattga acttactgat aatgccataa ctgatgcaaa tactggtatt aatatctttt
     7861 tcttcacgat aaacctccta aaattttccc ataattatct tatgattcta ttttgtaggt
     7921 gaagtgtacc taaggataaa atactaatac acaatacatt aataaaagct ctatctgtaa
     7981 cttttttgta aaccacttta tataactttt atagtattat tatattaata aaataaataa
     8041 attagcttat ccaatatgtc acctaaatat acattattta cttaattata taatatgggt
     8101 ctgtaaaagt aaagaatttt gtaccattcg aggttaaagt gcgcataaat attgttttat
     8161 gtgttttttt atgcgctttt atatggcgta tattttttga tggatttagt ataaagttag
     8221 atattctgtg aaatttttaa ccctacataa atcaaagcct atttcctaat agtgattctc
     8281 aaattctaag ttaaaaagat gaaaattttg gagaatataa atattaaaaa ttaagtatga
     8341 aaagattgtc ctagcagtaa tcttttcata cttaattttt ttagataata tatcaatagc
     8401 aactatcatt aatatacaat agttaaattt tttactaact tttttaaata cattattctc
     8461 aaagattaat ataagaagaa tgcttaaact acttactata gcaactttga aattccattt
     8521 taaatgaaat tcaacataca cttttccgaa ttgtgtttta tagtatttta cacctgaatt
     8581 tatctaattt tttaaaatta taaaccttat aattaataat ttatttcact tatttaagtt
     8641 ctttataagt atatccttgt gtactatctt gactattttt tattcttggt atataagtat
     8701 ctatttttat aaggatatat ttatttctca acaaattact attcaaaact ttataattaa
     8761 tatctgttaa aataatattt atttaatcat tcaatagact gtcataatat tctataccaa
     8821 cttctatttt atcagagtct ttaggtatca aacctaatga ttcacaattt attttatatt
     8881 cttccctcat atttttagga gcatctgcat atgtaaatcc tataactgaa aaacgtatac
     8941 tgctaacagt tcgtaagtct tcaaatcctt taggtaatac atcaagatta acaatactag
     9001 ttgaattaac cttcaaaaaa gtaatagaag ataataaaca taaagttaat gccattaata
     9061 taccattctt gtacttttca ttaaacatat tcataactct ctttttaata tcagattgct
     9121 tatgaagtcc agctataaat ttatttgaag tatttgaacc ttttctcatt gcatttagaa
     9181 ttgttaaagc ataatccttt ttttcctctg aatttcgatt ttttaaaact ctttcatcac
     9241 aataaagttc acaatctaaa tctatatgtt tatccattat atatataaat ggattaaacc
     9301 aatatactgt ttttaaaaac aggattacat attttaaata aaggtcccta ctcttaaaat
     9361 gcataagctc atgtctaaaa atccagtcta actctttcaa tttatactca tgtggtggca
     9421 aaagcacaca tgaattaaaa aatgctggtg tttcaacttc ataagagtat ttgagtttta
     9481 tatcttttgt tatattaaat tcttctaata tatttttata aagatttaca atctctccat
     9541 catcaacatc ataagataag tcatttatta aatttttaag ttttatatat ttaaatatag
     9601 tgtaaattaa ataaactact acagttataa tccaagtgta caatataata ttattactta
     9661 tagttgaaac attattaaat ccctctaaat ttatgttatt aatattaatg tgttttttac
     9721 ttctcaagat atttattgta aaagtataat atgtaaatgg taaaaataat ttaataacaa
     9781 ctatcatcca tatataataa ttaaattttt tgctaaatct tttaaataca tttttcttga
     9841 aaatcaatat cataagaatg cttagactac ttactataac tgttctaaaa atcccattta
     9901 gaataaagtt agacatacat ttttctccta tcttatttaa gagtatttta tgtttaagtt
     9961 tatttgcctt ttaagttttc atattatctt tattaattaa aaagatacat tttttgtaac
    10021 agataactat ttttatcatt ttataattgt gtaactcata atttatttaa actcccctat
    10081 aattaattat agcttagtaa tgattcctat gcatcaatca tatttaatta tttcaactat
    10141 ctataaattt catacttaaa cacatataaa attgaatcta taataaaatt ttcaattgct
    10201 taaatataaa aaattcataa tatcaacatc aatattaagt ctaacttatt tttttaaatc
    10261 catacaatct ttataaaatc taggaataat ttctattgaa tctgaatctt ttggtactat
    10321 tccattgact ctacagtttt cttcatgctc ttttctaagt tttataggtg catctgcata
    10381 tacaaaatct attgttacaa acatgtcttc ttgccttcct tcaaacgtat atcttgacct
    10441 ctctaagaaa tcattctctt caataatact agttgaatcg aatttaaaaa atgtaataga
    10501 agaaaacaag cttataatca aagcccttaa gataccattt ttatgttttt cactgaacat
    10561 gtttattact ctttttttaa tatcagattg tttatttaat ccagctacaa atttatttga
    10621 aaaatttgta cttcttttca ttgaatttac aatagttaga gcatattctt gcttttgttg
    10681 tacagtacaa ttttttaaaa ctctctcatc acaataaagt tcacaatcca aatccatata
    10741 tttttccatt atatatataa atggattaaa ccaatatact atttttaaaa ataatactag
    10801 atactttaaa ttaaggtctt tgcttttaaa atgcataagt tcatgtctaa aaatctaatc
    10861 taactcttct aatttgtaat catgtggtgg taaaaaatac attctaaatt acataattta
    10921 tcaagttatt tataagttaa aacaaaaata gcttacttca ttgtaagcca cataatttaa
    10981 gggctgtact atgtacagcc cctttatatc ttaaataatt atatcctatt atttattaag
    11041 agtaaatctt agtaccatcc tcttaatttc atagcttcag caactttctt aattgaatgc
    11101 atgtaagcag cttctctcat tgtaacattg tactcttctt tgattttcca aatagattca
    11161 aatgctttaa ccatagctat ttcttctttt tgctctactt cttcttctga ccagtagtat
    11221 ccatataagt tttgtaccca ctcgaagtaa gaaactgtaa ctccaccagc attagttaat
    11281 atatctggag taagaactat tcctctttca gcaaatactt catcagcctc tggagtagtt
    11341 ggtccattag cagcctcaca aactaattta gcttttatag attcagcaac ttctttagtt
    11401 atagagtttt ctaatgcagc tggtattact atatcaacat ctgaagccca gaactcttct
    11461 aaagatattc tcttagctcc tgggaagttt aataagttac catgttcttt catataatct
    11521 aacatagctt gaccatctaa accattttca ttgtatatag cataagaacc ttctgattta
    11581 caccattcag ccatagctac aacagtacca ccaagttttt cacagttaag aactgtataa
    11641 gaaccaacgt ttcctatacc ttgaacagct attttagctt ttttcatatc tattcctaat
    11701 ttagcagcag cttctcttgc agtaacagca acaccaaatc cagtagcagc tgttcttcct
    11761 aaagaaccac caaattcaac tggcttacca gttataacac ctatagaact ttgtccagtt
    11821 aatttattgt actcatcaac catccaagac attatttgac cattagtatt tacatctggt
    11881 gcaggaacgt caactttctc acctattaat ttatatattc catctatgta tcctctactt
    11941 aatctttcta attcaccttg agataaagtt gatggatcta ctattattcc acctttacct
    12001 ccaccatatg gtatacctgt tacagaacac ttgaaagtca tccatataga taaagctttt
    12061 acttcgtctc ttgaaacatt ttgatggaat cttattccac cttttgttgg ccctactgca
    12121 tcattatgtt gtgatctaaa tcctttaaaa gtttttatag aaccatcatc catttttact
    12181 ggaattgaaa cctctataac tctcataggt tcttttaata attcataaac tgctggttcc
    12241 atacctaatt tatcacatgc attttttact tgagattgcg ccatctcgaa gacatttaca
    12301 tcttttcctg acatttgaaa gcccccttat aaatacgtta taattatgta tactccattt
    12361 agaaaaaacc atttcctaaa tttacagttt aattatagca cactttattg caaattagta
    12421 tatcattttc tcagtttatt ttttaacatt ggaggaagtt tattttttta attttatgaa
    12481 tgttaatatc tattttttgt acattaacta aagtcatttt ctcaatagac ttttttattg
    12541 tctgttgtat gtcttcaatt ttttttatag tttctaaatc attgatattt atacttacaa
    12601 aaatattcat aaaattattg caattctcta tattgatttt atttattcta tcaatgcttc
    12661 caaagttgta tacttcatat tcaataatct gtttaattac atcagcacta atataaaact
    12721 ttcctatata actaaaagtt ggtcttataa ttgttttttc taaaactacc atattcctat
    12781 tatttccttt tctaaaaagt ctcttcaaag aatttatact aagaccactt gccatacttt
    12841 ttatctcaac tgctggaaca ggaattacat gatttccttc ttttctagct tgttttgcta
    12901 tttctatttc atatttagta cttatatctt gtatatttat aaacttatag acccttccaa
    12961 ttgacaatct ctctacaatt tgattaacca ttttttttga tgtcccaata ataagaattt
    13021 ttcttatatt ttctttttta attgcttctc taacttcttg tctatgctcc aaattataaa
    13081 aaatagccct tttaactgct tctatagtag tatttgcttg ttttgctgat atcccagcta
    13141 aaaccttgtt tttgtatatt aaaatcccat catcaattat atattctata tcattttcat
    13201 atgcgaactc taaagcctta aagctcttcc ctgtgccact tgacccaacc aaagcatata
    13261 cttccatcat atatctcctt ataaaatagc tttaactatt tattacaaaa ttttatttac
    13321 tttatagatt aaatttatta tatcattaac agtttaatat tatatccagt accaaaattt
    13381 ataagcaaaa aatatactac aacatgaaat ttctttacaa aaaataaatt tcctttaaat
    13441 aaaaaattta ttgaaaaaat tttacttttt taaaaaaagg actataatat attttaagca
    13501 gggaaactta ctggatttac attagaagga gctggtaata tgaatattac aaaaaatttt
    13561 ttaaaagact atttagagaa atttggtgaa acaccatttc tagttaggct taaagatgag
    13621 gaagaatttc taattggaga gggctcccct cagttcaaag ttatagtaaa taatgatatt
    13681 agcaagtctg aactattaaa aagtacatct ttagcacttg gagaagccta cataaataga
    13741 gacattgaag ttgagggaga tttattttta actttaaatc tacttttaaa acaaatagac
    13801 aaattcaata ttgataattc agctgtaaaa catctattgc actcatcaaa ttcaatgaga
    13861 catcaaaaga aagaaataca tgcccactat gacattggca acgattttta tagcttatgg
    13921 ttagataaga cacttagtta ttcttgtgca tactttagaa atgataatga tactctttat
    13981 gatgctcaag tcaataaagt tcaccacata ttaactaaac taaatttaga ggaaggtatg
    14041 agccttctcg atattggttg tggttgggga tttttactaa tagaagctgc aaaaaaatat
    14101 aaaattcacg gcgttggaat tacacttagc gaagagcaat ttaaggaatt taacgcaaga
    14161 attaaagaag agaaccttca agactatctt gaggtaagac ttatggacta tagagaatta
    14221 aaaaaatcag accttatgtt tgatagagtt gtaagcgttg ggatgcttga acatgttggt
    14281 agagaaaact atgaactttt cattaaaaac gtaaatgctg ttttaaaaga tggtggattg
    14341 tttttacttc actatataag tggattgcag gaatcttatg gagacccttg gataaaaaaa
    14401 tatattttcc caggaggagt tattcctagc ctaagagaaa tgatacatat ttgtagtgat
    14461 tacaaatatc atactataga cgtagaaagt ctaagattac attatgtaaa aaccttacta
    14521 tactggcaaa aaaatttctc tgagaatctt ccaaagatta aagaaatgtt tgatgataag
    14581 tttataagaa tgtgggattt atacctttgt tcttgtgctg ctgctttcaa cactggtatt
    14641 atagatatac atcaaatact tttcactaaa ggtataaaaa atgatttacc tctaactaga
    14701 gagtatatgt ataattgttc aaaataatat tttacaaatt gaatataatt taaatttaat
    14761 tgcaaaaaaa tagagctatt tctaaataag atttgtcatt tctcttattt tagaataact
    14821 ctatttattg atttactgta tttataaacc ttacttcacg tatatactat atactataac
    14881 aaaattctcc attttctttt atattaaaaa agtctgcata acatacatca aatatcctat
    14941 tttctaaatc atatatttca actttatttt ttattaaata agttaataca cctacatatg
    15001 aaatatctcc ttgtataact gctccataga ttacattatc tttaaaaaca aactttttat
    15061 aatcattaat tccatgtctg gttaatactt tatagctatc atctacaggt gtattcattc
    15121 ctatagaaat agttggtata tccatgaaat tcatactgtt tttaaaagca agttcatctt
    15181 ctatcttctt atcttttcca accatattat aggcagctac aattccttgc tttactgcca
    15241 gaggccaaat agcattttta cctacaacat ctcctgctgc atatatgtct ttttgtgttg
    15301 tttggcacat atcatctatt attatacctc tatcatattc tattcctgtt ccatctaaaa
    15361 agtcagcatt tggtttaacc cctgtagcta caattaccat gtctgcatct aaaacttcac
    15421 catttgaaaa tgcaacacct gtaacattct tactgttatc caatacaatt tcttgtattg
    15481 atgcacttgg gtaaaatttt acaccttttt ctttgaactt attttcatac actgatgctg
    15541 tatattcatc caattgtctg tctaaaatgt acttttccat aaaagctaca gaaatattta
    15601 actgctcata tttaaataat cccactaatg catctatacc aactaaacca gcacctatta
    15661 taactacatt tttagaattt tgtgcttttt cttttatttt ataaatatca tctatgtttc
    15721 tcacagaata tacaaaattt ccatctctta aattttttat aggaggaata gcagaagatg
    15781 cacctgtagc tattaaaagt ttatcataat ttacagtaat gtcttctgtc tgaactacct
    15841 ttttatttat gtctatacct ttaacagtct tacctgcaat ccattttaca ttattttgct
    15901 ccataaaatc ttcatcaaca aaatttattt gttttaaagt tctgtgttca gatataacat
    15961 gatgcaacat acatcttgaa tatacgtttt catctttaga aattactact atatttgaat
    16021 ctttatctaa ttctcttaat gtttttactg catttatact agctgcacta gcccctaaca
    16081 ctacataatt catcattttc ctccttctgt aattcaattg ctccacttgg gcaattagct
    16141 acacatctag gatactccgc atctttacat aaatcacatt taagtatgtt ctgcttgctt
    16201 ctatcatctg gctttaataa tccatatgga caagacatta cacacatata acatgaacca
    16261 catttctctt catcatatga aacgattcca ctttcactat ctttatgcat tgcaccactc
    16321 atacatgcta atacacattc aggttcatca cagtgtctac aaagaattgg aactggatta
    16381 ttatgtttac tatctaattc tatatgccct ctactatcat tatctatatt ttctaaatca
    16441 agagtgtaca tgtcataatc tttattgtgt tttagcatac atgctagtac acagctctta
    16501 catcctgtac ataaatcttt atttataaaa attctatgca ttgcattcca catcctttaa
    16561 ccctaaattt tttcttctat ctattattat ttcttctaat tgattagctg aagatttagg
    16621 gtctggattc actataacat gtcctcctgt taagtctttt aatttttctg ttaatacttc
    16681 tgtcaccaat tttcctcctg ttataaatgg aggtaaagct aaatgaagag gtaagccaag
    16741 ggcaagacca aacgctccat cagctaatgc ttgttcttcc aaccattgtg gagctgaaag
    16801 cactaatggt aattgtggta ggtcaattcc aagttcagct gctaattctg ttgctactat
    16861 ttctagtctt cctatagcta gacatggtcc aaagtttaat actggtggta ttcctaaagt
    16921 cttacatact tcttttaagt tttctcctgc taattcttct gctccaggtg acataagacc
    16981 aacattttct aatcctccag tagaacatcc tgcagatagt actattatat cttttttaat
    17041 caattcttta gtaagttcaa cagtatttac atcatgtcct cctgctgtca tatttgaaca
    17101 tcctacaaca gctgcaacac ctttaatttt tccttctgca attaaattaa taagaggttt
    17161 ccatgaatct cctaaaaacg ctttcaggtt cttttcactt acaccagtta aagattgttc
    17221 aaatccatgg tcttttggta tatctatttc aatacttcct cttctctcct tataagactc
    17281 caatgctttt tctattaaag tgttactaag ttcatctaat ttacttctgt ctaaacctat
    17341 gtattctgca ttcgcttttt tagcaacatc atctaaacaa accattttta ctttatattt
    17401 atctgctatt ggttcaagcc ctggtatagt acagttaaat tctgaaagaa ctatatctat
    17461 tgctccagtt gataaaacag cctcacttgt aaaattgtta cctgcatgtc cagcaaatac
    17521 ttcttgataa tgttctcctc ttaattgtaa atcttgacca acacatgtac atcctactag
    17581 cttaaagcct tttgcaccaa cagattgagc taattttata acatcttcat cttttaatct
    17641 atcttggaaa tttgcaaatg ttgaatgttg atggcctgtt atcattatat ttatgtagtc
    17701 tgggtctatt acattaaatc ctacaggagc cattcttata actggttctc ccaacataac
    17761 atcatttaaa agattagtta gtgtaagacc atataatcct gttgatatac ctaagttcaa
    17821 acaattaact agcatgtcta ctgggtcact atttaaattt gttgatgatt ttactattgc
    17881 atcaaaaact tctgactttg caccaccagg cattatacct aactctttcc actttttcac
    17941 tctaggtgca taagctattt tttctactaa ttccatttta tcatctcttg atttatacaa
    18001 atcgttgata actttgtctg caacctttat acatttatca tacttttcat cactttctat
    18061 tccaaacatc tctgctaatt gatttaatgt tttttctcct ttaacaacac ctttagttat
    18121 tccaacattt tttaaattct tagctgtatt ttctaccaca tgtaaataac aagctgctcc
    18181 tgatgctact gctcttaaaa agtttcttgc tactatagtg tctgcatctg ctccacatat
    18241 acctcttggt gatttaggag ttactctaca tggtccattt gaacagagtc tacaacaaac
    18301 cccctgaagt ccaaaaccac acttaacttt ctgatcttct gttctatgaa atgctgtttc
    18361 aacatccttt gaagctacaa aactttctaa tttcttgtct gcactttcgc acattttaca
    18421 agtgttacaa gccattacaa attccccctt atatttttat attaaaaaag tagattaaat
    18481 agctttatta taattgacta taatttaact attaaaatct acttatttaa taccacgatt
    18541 taccataccc taaacaaaat ataaattatt aaaataaata tatatatatt aaattcttat
    18601 acaccaaatt tttacattaa acttctatgc accacattta tacatattaa attcttatat
    18661 attaaattt
//
LOCUS       DAEPXW010000076        18609 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.077, whole genome shotgun sequence.
ACCESSION   DAEPXW010000076 DAEPXW010000000
VERSION     DAEPXW010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.077"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            238..1398
                     /locus_tag="KRM55_002637"
     CDS             238..1398
                     /locus_tag="KRM55_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH1594860.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKYNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1740..1901
                     /locus_tag="KRM55_002638"
     CDS             1740..1901
                     /locus_tag="KRM55_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594861.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2094..2723
                     /locus_tag="KRM55_002639"
     CDS             2094..2723
                     /locus_tag="KRM55_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBH1594862.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2962..4221
                     /locus_tag="KRM55_002640"
     CDS             2962..4221
                     /locus_tag="KRM55_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH1594863.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4480..5475
                     /locus_tag="KRM55_002641"
     CDS             4480..5475
                     /locus_tag="KRM55_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBH1594864.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5721..6788
                     /locus_tag="KRM55_002642"
     CDS             5721..6788
                     /locus_tag="KRM55_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBH1594865.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFVEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7322..9232
                     /locus_tag="KRM55_002643"
     CDS             7322..9232
                     /locus_tag="KRM55_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH1594866.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMLF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9295..9918)
                     /gene="ytaF"
                     /locus_tag="KRM55_002644"
     CDS             complement(9295..9918)
                     /gene="ytaF"
                     /locus_tag="KRM55_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBH1594867.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10106..10750
                     /locus_tag="KRM55_002645"
     CDS             10106..10750
                     /locus_tag="KRM55_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1594868.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            10964..12022
                     /locus_tag="KRM55_002646"
     CDS             10964..12022
                     /locus_tag="KRM55_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBH1594869.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            12126..13310
                     /locus_tag="KRM55_002647"
     CDS             12126..13310
                     /locus_tag="KRM55_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1594870.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            13517..14230
                     /gene="rpsB"
                     /locus_tag="KRM55_002648"
     CDS             13517..14230
                     /gene="rpsB"
                     /locus_tag="KRM55_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBH1594871.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            14309..15220
                     /locus_tag="KRM55_002649"
     CDS             14309..15220
                     /locus_tag="KRM55_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBH1594872.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            15305..16009
                     /locus_tag="KRM55_002650"
     CDS             15305..16009
                     /locus_tag="KRM55_002650"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBH1594873.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            16035..16592
                     /gene="frr"
                     /locus_tag="KRM55_002651"
     CDS             16035..16592
                     /gene="frr"
                     /locus_tag="KRM55_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBH1594874.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDALLSKKEKDIMEV"
     gene            16595..16798
                     /locus_tag="KRM55_002652"
     CDS             16595..16798
                     /locus_tag="KRM55_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594875.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            16827..17561
                     /locus_tag="KRM55_002653"
     CDS             16827..17561
                     /locus_tag="KRM55_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBH1594876.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            17574..18353
                     /locus_tag="KRM55_002654"
     CDS             17574..18353
                     /locus_tag="KRM55_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBH1594877.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         7649 a         1854 c         3230 g         5876 t
ORIGIN      
        1 aaataaaaat tttagtaata aaataattgt tgaaaaagat tttaaattca gattattcat
       61 ttctaaagta attaatgtgc aaatctttat taatatatgt caatagttag gtatatatgt
      121 atttaattag tatgatatag ataaaagtat ttattttaat tgtctattat ctgaaaaagt
      181 ttttacttag aaatcataaa aatcaaatta attaggaaaa gaaagggtgt gtataatgtg
      241 attgagactg gatttgtata ttgtagtttc ttggttgtat tcgtaggtgt aatttttttt
      301 atggttgata aattgaaatg gaaggtattt gatgttatta atccaatgct tttaatatac
      361 ttaggttcag ctatacttgg atcatttggt ttatttgcac agaatgaaga tgttggaacg
      421 tatcaaaaca taataacagt gaacttcctt ccattaatgt tagtgttttt gttaattcaa
      481 tgtgatttaa gaaaaatatt aaagatgggg cctaaaatgt tattatcatt tttctgtgct
      541 acatttacat ttatgcttgg atttgttata gcattcataa tttttaaaaa ttcaatgggt
      601 gcagattcat ggaaaattct tggggcagca tctggttcat ggataggtgg ctcatcaaat
      661 atgattgcag cagctaatgc tctaggagtt gcagaagaag gacttagtta tgcaatactt
      721 atgggttcta taggatatac agtatggatg tctgtttgtc taatgtctgt gaaatttgga
      781 cctaaattta acaaatggac aaagtgcgat acaagtttta tagatgaggt tacatcaaaa
      841 cttgaaaaag aaaataaata taatacggca cctacgtttg tagaacttat gattttactt
      901 tctgttgggt ttggagttgc gtcttttgca caaattgtat ccaagatact tccaacttca
      961 ggtatactta atgaaactat gtgggtagta cttgttgcat ctacagtatc aatattattg
     1021 ggtatgacaa aaatatcaaa gcttaaaggg agtacactgg taggaaatgt gtttatgtat
     1081 ttactccttg cagctacagg tagtaaagca aatttctttg gattgtcaga agcacctgtt
     1141 tacataatgt ttggattggt agtagtcctt gtacatgcta tttcatttat agggcttgct
     1201 aaactattta aacttgattt atttacttgt gaagtaggaa gtatagctaa tataggagga
     1261 gtaactacag ctccaatgat tgctggggtt cacaatcctg tattaatacc agtaggtgta
     1321 cttatggggc ttctaggaaa tattataggg acttattgtg ctcttatggt aactcaaata
     1381 ttacatatgt tagcttaata aaaatatggt ataaaattaa taatttaaat aagaaaagtc
     1441 atttcaattt aagcagaagc ttttactgaa atggcttttt tgtttgacaa gataatctat
     1501 ttcaagaaga tgttttgaca tatttagtgt ataatattgt aaaatttact aaaaacgaga
     1561 tatatttaat ttttatattg aatcgaacgt ctgtatgatg tataataaat atacagaacg
     1621 aatgtttgta gaacgggtgt tttttgaatt tattttaata atttatgaat atatatcaga
     1681 atgcataaat atatttaaat ataaagatta aaaagaattt aaaggagtgt tgataactta
     1741 tgataattcc atcaagaaga atacaagata taacattaac aaatttaaaa aatggtgaag
     1801 taactttaat tgaattggat gaaatataca agaagatggg atttttattt gttgttagtg
     1861 aaggcaaatt gaaaaagata aaaaaggaga atcatcatta gaaatgaatg aaataataaa
     1921 tattataata gtttataaaa cctaacttat gtagaatata aatacttaag ttaggttttt
     1981 ttgtgataaa gtttataagt actcaatttt ataagataaa taatggtctt aagtgaaaag
     2041 taaataagtt taaattttag taagtattat attgcataag aggtgatatt attatgaaaa
     2101 tagtaaccta caatattcat aaaggtatgg attcaaataa tagattaact ctaactaaaa
     2161 tggggttata tttaaaacaa ttggattgtg atgtaatttg tttgcaagaa gtattatatc
     2221 ctcaattttt agctttaaaa gctgttttaa atatggatgg tgtctttgcg acaaatgtaa
     2281 aaaaagtaaa tatgatatat ggtatttgta catttacaac atctaaaatg ttaaacagta
     2341 atcatttttt cttaactagc aaaaaagaac aacggggagc tctttgtata actatagatg
     2401 catatggaag aattataaat gtaataaata ctcacttggg acttgatagg caggagagag
     2461 caaaacaatt agacgaaata atagactata ggaacagatt agtggggata gttattttat
     2521 gtggtgattt taatgagaaa aatgtctttt taagtatgtt taatgatatg gctatttcac
     2581 taaacaagtc ttacttacca acatttgaaa aatcaaactc tagaatagat tacatttttg
     2641 ttaataaaaa tactgaacta aaaggataca cagtagaaaa aatttacctg tcagaccatt
     2701 atcctgtaat aggttacatt taaatttcaa tataaatgaa attagttgtt ataaaataaa
     2761 caattttttg ttaagaaata gtaaaagaaa tataataaaa aatatcaaaa ataaaactaa
     2821 ttataagaca taaatttaca ataaagttac atttgattaa attccttgtt taacaaaagc
     2881 tattcaaata taatctaagg tagttttgaa atgggaactc tattatgcaa atttaagcta
     2941 gtgttaaaat gaggtgaagt tatgggcaga agaacaacaa gagtttcaag attaggtaaa
     3001 gaaaaaaaac gaagtgtttt aattgtattg gcagctttag ttctaataat gggtggattt
     3061 acttattttt ttaacagtaa atttctgtac aatgggaaaa tcgctaaaaa tgtatatata
     3121 gaaggagtaa atgtatctga tatgactaaa gcagaggcat taaaagctat aacagataag
     3181 tatactccag aagatttaaa tcttgcttat gatgggaaaa aatatacaat atcaccaaaa
     3241 gatattgatt taaaatatga tacagaagat gttgtaaaag atgcttatga aagtacaaaa
     3301 aaagggtcct attttcaaaa cttaaaaaaa tatattgata taagagtgaa taaggcaaat
     3361 atgaagataa aagctgaata tgatgaggca aaacttagtt ccaaagtgtc ttctatagca
     3421 gatagtataa atgttaagat gaaaaatgct tctattagtg ttggaagtgg tggactaagt
     3481 tatacagact ctgttgtagg tagagaattt gatttggcag caaataaaga gtctatatat
     3541 aatatgataa aaaataaaga gcataaaact ttagaactta aagtaaatct tcaaaaacca
     3601 gatataacaa ctgaacaagt aaaaactgta aattctgtta taggtcaata ttcaactact
     3661 tattcacaag ctgtagaggg taggtcatat aatgtaggat tatcagcaag aaaaactagt
     3721 gatgtattat taatgccagg tgaagaattt tcatacaata aacttacagg acctagtaat
     3781 aaagcaaatg gttacaaaga tgcacctgtt atagtttatg gtaagctaga acaatcagca
     3841 ggaggaggtg tttgtcaaac atcttcaaca gtttataatg cggctcttct ttcgggtatg
     3901 gagataactc aagttacaaa tcattcatct gcatctactt atgtgcctaa agggagagat
     3961 gctactgtga gcgatggagg attaaactta aagtttaaaa atccatataa gcatcctgta
     4021 tatattaaaa attatgcagg tggaggaagt gtatcatcag taatctatgg taattctggt
     4081 gacaaaccaa atatatctat agaggtaaaa caaactggtc agaataaata ttctacatat
     4141 cgaatattta aagattcaag tggaaaggtc ataaaaaaag aacatatatc aaatagttct
     4201 tataaagaat taaaaaaata gataattttt tagagaaata tttgtaatat aaaagggagt
     4261 gtctcaaaat gaacttttta gtttatgagg cactcttttt ctgtgaaatc aaatatattt
     4321 tcatcatttc aacaatacaa aagaagcgta tctctatttt gagacagcct tttttgtaaa
     4381 aattaacact attagttctt gttttaatat tacaatcatt aatatataga aaatattcct
     4441 atatattggt ataattgtaa atagatttag ttatataaaa tgtatgagga ggtgacatgg
     4501 ttgaatttta taggcaatag atatgaggta gtaaattctg acgacgtttt agaaattaac
     4561 aaaatctata aagctagaga tgttttttac aggaaaaatg tgttaataaa agttataaag
     4621 cacaataatt atatctgtga agattttgtt tcaaatttaa ttgatgaaag tactgcttta
     4681 gatgagataa actctcctta tatactaaaa ataatagatg ttgggattca ctgtacagaa
     4741 gaaacaacat tatattatgt tgtaagtgaa gactttaatg gtatcggact agatgaatta
     4801 attctaggta attatcttca tttagaagca attgtaaaca taatgataca agttttaaaa
     4861 gctttagaaa tgatacatag gaatcattca tatcatggta gtttaaaatc gagtagtata
     4921 atagtagata cagaatacaa tataaaaatt tgtgattttg gaattacaaa agcaaataat
     4981 ggggttaata caagaagcta tggaaacagg agatatttat gcccacatca actatgtata
     5041 aattatactg ataaagaaag tgattttttt gcaacaggtc ttattctatt tgaatctata
     5101 tttaaaaaat tgccttttgg agaatcaaat tcagaagaaa aaatgctaca atctattgat
     5161 aagggattag attggaatag tataaaagca attaatggaa atactgaact tataaatgtt
     5221 ataaaaaggc ttcttggaag aaataataag tataccagag ccaatgatat tattattgat
     5281 ttaagtaaag taatgtatga aaaagcatat atagaagttg aagatgagaa agaagaagag
     5341 cagaaacaag acaaagttat acaagttaaa aaagaatata aaagtaaaat gagaaaaaaa
     5401 ttacataaaa aacttgttgt tgccggtcta gctatagtca tgatttcaat gattattatt
     5461 agttccataa tataaaaatt gtatattaag tattttaaaa tcaatgtcta taaaggatat
     5521 acatagaaat tttagtgtag tcttaaatta tgaaaggaag tggttattat gttaacaaaa
     5581 aataatgagg tattaaacgt ctaggagtat tttaacaaat agccacctgc ttttacagtt
     5641 tagaataaaa aagctgtggc taaaggtcac agctttttgc tactttttaa aggcaggaga
     5701 atattaaaaa ggagcaaatt atgagcaata taaaaataat agcaagtaat aaatgttgga
     5761 ttgaagatat agcaaggaaa caacttgaag atatttcaaa gttaaatgga attttaagag
     5821 tagtaggatt acctgactta catgcaggta aaatacctgt aggtttagca gttgagacta
     5881 aaaatattat ttatccacat ataattggaa atgatatagg atgcggaatg actttattta
     5941 aaactggagt tctaaaaaag aaatttaaaa aagacaaatg gattaagtca cttagtaaga
     6001 ttaaagattt gtctgatata gaaataaaaa acacatataa agaagaatgt ccaattttaa
     6061 atttaggaac tatagggagt ggaaatcatt ttgtagaaat tcaatgtata agtgaaattt
     6121 ataataaaga acaatttgaa caattaaaat tttcatctga tgatattatg atgttagttc
     6181 actgtgggtc aagaaattat ggagaagata ttttaaaaaa attttatgat aaagatggac
     6241 ttgaagttga aagtgagaaa gctatagatt atattaaaaa acatgataat gctttaatgt
     6301 gggcagagcg taatcgtgaa gctatcagta aaaaaattat gcagtcaata ggtacatctg
     6361 gagatgttga aacaatattc tctataaatc ataactttgt agagaaaagg gaagataaat
     6421 ttatacatag aaaaggtgct gtttcaagtg aaagaggagc tgtgattata ccaggttcaa
     6481 gaggcagtct atcatatata gttatgccta ctgaaaatac agagatatct ttatattctc
     6541 tatcacatgg agcaggtagg aaatggtctc gttcagtttg taaatctcgc cttaaaagta
     6601 agtatagtaa agatactata aaacaaacta aatttaaaag tcagattata tgtaatgatg
     6661 taaatttatt atttcaagaa gctccagagg catataagaa tatagagcag attattgaaa
     6721 gtttgataga atatgaactt attcaagtag tggcaactat gaagccattg attacttata
     6781 aaggataatt tttaaagtta aaaaagatta aaattatatt ataaatagct aattttatgg
     6841 aacatttaaa agtgttttat tattagctat ttttttattt tgtagagacg ataatttata
     6901 gagctaaatt ctttgatata taatgattac aaagttagac tgtattggaa actgcacata
     6961 catgaattga tgacaatata agtgattcca aaatataaat gaaagtataa gcttattttc
     7021 actataaaaa ttttcactgt acaaaaacat taatgacatt atttttattg acataaatat
     7081 ataatttatg gaataatatt agaagcactg atataagtgt ttaaataagg atagaaaagg
     7141 agaagtgttt tatgaaaaaa aatactaaca ttaatgagtc cggagttaaa cttcttaata
     7201 aataaggagt ttgatatata ataactcctt atttattaag ttgttcgcaa aataactatt
     7261 atcaaagtaa atgatagggt gatttaaaag acgataactt ataaataaag gagaaaaaat
     7321 aatgaatagt aatacatttg aaagattaca actaaatgaa gttaaagaat taataaaaat
     7381 acattgtgta agttcactag gaaaaaattt aatagataaa ttaactccta gtgggaatat
     7441 tggagtagta agaaggaaat tagcagaaaa taaagaagct agaaagataa ttgaaaatag
     7501 taatcacata ccacttgaag gattgtttaa tgcaggttct acaatagata aaattgaaaa
     7561 aggaatgata atagaacctg ttgaacttgt aaatattgaa gattttttaa gaggttgtag
     7621 gaagatgaaa gcttttatgt tagaaaaaga attttattca cctacattaa gttcttatgc
     7681 cttaaatata acagaatgta aaagtataga agatgagata aattactgta taaaatctaa
     7741 taaagttgat tctaatgcta gtaaagaatt aaaaaagata agacgaaata tagaaattac
     7801 agaaggaaag ataaaagata gattaaataa atttataaca tcaactgtaa ataaaaagta
     7861 tatacaagag tttataataa gtaaaagaaa tgatagatat gtaataccaa ttaaatcttc
     7921 ttataaaaat gaagttaatg gtactatatt agatacatca tcaaaaggaa atactgtatt
     7981 tattgaacct attagtgttt caaatttaag tacagagtta actatgctaa aagctgatga
     8041 aactattgaa gaatacaaaa tattatctta tttaacagaa cttatatttg agaagataag
     8101 tcagataaaa ttaaatatag agatactttc agaatacgat atgttatttg caaaagctaa
     8161 gtatagtcaa aaaataaaag gaattactcc aaaaataaat aataatggct atataaaaat
     8221 aattaaaggt aaacatccac ttctaacagg agatgcagta cctttagatt ttgaaatagg
     8281 caaaaattat agaagtctta taataacagg tcctaatgca ggaggaaaaa ctgtaaccct
     8341 taagactgtt ggtttactaa ctttaatggt tcaatgtgga tttgatattt ctgcaaaaga
     8401 aggtagtgaa tttagtgtat ttgaaaaagt ttttgtagat ataggggata atcaaagtat
     8461 tgaaaatgcc ttaagtactt tttcatcaca tataaaaaat attgcagaga ttatgagttt
     8521 atcaaataat tctactcttg ttctgtttga tgaaatagga agtggaactg aacctaatga
     8581 aggagctggt ttagcaatat cattattaga agagttttac aaaatgggat gtataactat
     8641 agcatcaact cattatggag agataaaaaa gtttgctaca ttgcatccag aatttgaaaa
     8701 tgctggtatg atgtttgata aagaaacgtt agaaccattg tataagttaa ctattggaaa
     8761 atctgaagat agtaatgctc tttttatttc taaaaaaatg ggaataaaaa atagagtttt
     8821 agatagagct aaagaatatg taattgatag aaactacaat ttagatttag ttaaaagaag
     8881 taagctacaa tctaatattg aagataaaaa tagttctgaa gtcattttaa actatacaga
     8941 ttataatgta ggggataagg taaaattact agatgaagat gattttggaa ttgtatataa
     9001 gcctatggac aagtttaata atgtagaagt attgtttaat gataatttta tttcagtaaa
     9061 tataaaaaga ttacaactta gcataaaagc atcagaattg tatccagaag ggtatgattt
     9121 agatgtatta tttactagtt ttaaagaaag aaaattagaa aaagatattc aaagaggttc
     9181 aaaaaaagct cttaaaaaga ttcagaaaga aattagagag aatagaaaat aaatataaaa
     9241 agcacaaaag aaagcaatct aaagagaaaa gtttatcttt agattgcttt cttattaaca
     9301 tatcttcata aatccaatga ctaacaagat taaaccactt aaccaagata agtttaaatt
     9361 tacgttttta acaaacatat ttcctagtaa acaaccaagt aatactgcaa ttatatttga
     9421 tattaaagaa aatagaataa cttgtatata attcacacct acaaggccac taccaaaacc
     9481 gatagctaat ccatctaaac ttaaagcaag tgcaagtgta aatgcttcag cagatttaag
     9541 cactttagat ttacttgtat ctaagacatc aggttcgata cttacattaa aatttaattt
     9601 aaggtctaac atattaaaat tataattctt tgagtgtata gattttttct taaaataaga
     9661 tttaaaaaaa ctttcaatta gtctagcact tcctaataaa aataaaataa agaaacatat
     9721 taacattgtt atattttgag gtaaaaaatc tctaactatt gtacctgcaa aaagcgatat
     9781 tgctaaaata gctgaacaaa ctacgctgat aattatattt gaatataagg gaactttaac
     9841 tttatttaca ccatatccaa agcttgtcac aaaggcatct atacaaagag aagtaactaa
     9901 taaaattgat tcaatcacag tagattaaca tcctttctct taaattttgt acttatatta
     9961 gttatagtat tgtaaaaatg gataaattgt tacagataat ccaataaatt gttgataaaa
    10021 ttccaacatc atacaacacc taaataacaa aagaatcata tcatataata atataaaacc
    10081 aatcataata aagcgggtga aaataatgga acaaaataat aaggttggga atttcggtga
    10141 tttgttgaag attttattag atgaaaaaga attatcaatg ggagaactaa gtaaaaaaag
    10201 tggaattgat aaatctacta tatctcgtat agctaataat aaacaaaagc caaatataaa
    10261 tcatttagaa aagatggcaa tacatttaaa tattaaccta gaagaactgt tgaaagcttc
    10321 aggatatgaa tttagaaaca gcaataatca aatatttaat gcagatagtg attttagtaa
    10381 ctttgatgat attcttggat ttgcaaattt aatcaatgat aagaacttta atggaaatat
    10441 tgaaaaagag ttaagtaagt gtaagttata tgtccaaaca gatgaaggta aaaaattact
    10501 ttttgataat tttaataaaa aaatagattc tattgaaaaa caaggtcaat ttacagatag
    10561 attaagacaa atgtatgctg atttttgtac agatggactt acaataaaga aatatttatt
    10621 gattggaagt atgctacttt actttgttat atcaacagat gtgattccag acttcgtgtt
    10681 cccaatagga tttatggatg atttagtagc attaaatata gttacaaaat tacttaaaaa
    10741 tgataagtaa gttttagaat catatttaat atataaataa atcaaagtat ataaaattta
    10801 ttatttttta tatgaaacaa attaaaagca caatgaagta gattaaaaat ttaaaactaa
    10861 gaatctaata tatattttgt aactatttaa gtatataaaa taaaataata tccaaactaa
    10921 tacaaaatag taataattgt tttgtactgg aggatatata tttatgaatt gtaaatggat
    10981 atctaaaata gatgagagaa aaaaatgtca tagagaagca gattcttctg gatattgtat
    11041 ctttcataaa gaaaataagt ctgatgaaga gatacagttg atgatggata ctcttcataa
    11101 agaagagata agtgaattta atggatttgt ttttgaaaat gaatttaatg cggaagaaat
    11161 attaacttac aattataaaa tactggattt ttctgaatcc atatttaaac aaaaagcaaa
    11221 ttttaaaaaa tatattttta aaaagaatat tatttttaac tatacagaat ttagagataa
    11281 agttttattt aatggttgtg tattcttaga aaactgtgat tttaatagaa ccatatttag
    11341 taaacactat ataaatgacc gtatatttga aaaagtgaaa tttaaaggac ctgatttggt
    11401 agttaataaa gtagaaaatt ttccacgaat ggatggaata atttttagca tgtgtacaaa
    11461 atttgtgtta aagaatgttg aatatggaaa aagtgagtat gagcatggca agataaatta
    11521 tagaatagct agaaatcaag caacaaaaat tggagaatat gagatgatag gattttacta
    11581 ttataaggaa agaatttata gtagtaaaat aatgaaacgt tctaattatc ctactttcag
    11641 tgattattta gttgaaaaat tttttgacca aatagcacgt tacacaacag gttatggaga
    11701 aaagccatgg aatatattat tagttattat agcaataata agtgtttttg ctttattata
    11761 cttatttgta ggcatagaaa gttcaaatag cacacttgta gctttagata taaataatat
    11821 aggtgattac tcactaagtg agattttcaa aatgtatatg gatttatggt attttagcat
    11881 ggctacattt agtacagtag gatatggaga tatggttgct acaagtttga ttgggaaagc
    11941 attggcaggt atagaagtat tttttggagt tacaatagga gcaatttggg catctgtgat
    12001 tattaaaaga atgataaggt aatatttgtg taaatatgga taggtattaa ttactagata
    12061 taaattgtac taaataggga aaatttaaat ataaatatac ttaataatcc aagaaggtga
    12121 aaaatttgaa aaatgcacta aaaaaaatta tatcattagc catgattcta gtttttataa
    12181 taccaaatta ttcatatgca gatgataaat ctgtagacaa gtattcaaaa acatctatac
    12241 ttatagacca agaaacaggt agagttttat atagtaaaga acctgatatg aaggtaccat
    12301 tagctagttt aagtaagatg atgacttttt tacttgcaat agaagctatt gaaaataaag
    12361 aagtaaaaga aactgataaa gtaaaaatag acaaatctat tgcatcagta aaagggtcaa
    12421 gttataaact taaagatggt gaagaagtgc cacttataga gcttatgaga ggtcttatga
    12481 ttgtatcagg aaatgatgcg gcaattgcta tagcaaaaca tatttgtaaa acgaaagaag
    12541 catttgtaga tagaatgaat aaaaaagcaa aagaaatagg aatgagtaat acacattttc
    12601 taaatccaaa tggtcttcca atatacgatt taagcaaccc caaaaaacca gcaaaagaaa
    12661 atatctctac tgcaaaagat atagctattc ttggaaaata catgtttgac cattatgaaa
    12721 aacaagtaac agctataact gatatggaga catatacaaa ttcagataga agttttgaaa
    12781 aaagcaatac aaatgcatta ttaagaatta taccagaagt agatggtata aaaactggat
    12841 atactggcaa tgctggatat tgcttatcat tttctatggt tgtaaataaa aatgataaaa
    12901 atgagaaaaa acgtagagta ataggggttg tattaggtac taaccataaa aataaaagaa
    12961 cctctgcttc attagctcta ctgaaatatg gaaaagaaaa tttcaatatg aaaaaagtaa
    13021 ttgataaaga tagctttatt ggtaagaaat atataaaagg aatgaaagag ttagaggtta
    13081 cattaaaagc aaaagatgaa ctttatacaa tattaaaaga tgatgaaagt ataaaatcag
    13141 aagttaagat taaaaatata gagtaccctg ttaaaaaagg tgatactatg ggtattataa
    13201 aatattatac taattcaggt gacttacttg gaagtgtaga tatagtaagt aataatagta
    13261 tagataacgt atcattaaaa acaaaattaa aaatgaaatt tgcaaattaa attcaaaaaa
    13321 tggtataaaa tacacaaaaa aatataaaaa tagaaaatat ggaaaaaata ttgttatttc
    13381 ttcacctctg tgatatacta ctagaggtga aaaaataaaa taaatcacac acagcattgg
    13441 gatccttaaa aggtgcctat tacatggttt tttagggaga agatcaagct ggaggtataa
    13501 aaccaggagg taagatatgt cagtaatatc aatgaaacaa ttattagaag caggtgttca
    13561 ctttggtcac caaacaagaa gatggaaccc taaaatggct aagtatatat tcacagagag
    13621 aaatggaata tatataatcg acttacaaaa aacagttaaa aaagttgaag aagcttacaa
    13681 gttcactaaa gaagtagctg aaacaggaaa gccaatctta ttcgtaggaa ctaaaaaaca
    13741 agctcaagat gcgataaaag atgaagctga aagatgtgga atgtactttg ttaatgaaag
    13801 atggttaggt ggaatgttaa caaaccacaa aactataaaa acaagaataa ataaattaag
    13861 agaattagaa aaaatggaag aagaaggcgt atttaatgtt cttcctaaaa aagaagttat
    13921 aaaattaaga gctgaaaaag aaaaactaga aaaatactta ggtggaataa aagacatgcc
    13981 tgaattacca ggtgcaatgt tcgtagttga cccaagaaaa gaaaacatag ctattcaaga
    14041 agctcataga ttaggtatac cagtagttgg tatagttgat actaactgtg acccagaaca
    14101 attagacttt gctataccag gaaatgatga cgctataaga gccgtaaaat taataactgg
    14161 tgctatggca acagctgtaa ttgaaggtag acaaggtgct gaggaagaag tagctgaaga
    14221 ccaagaataa taatttgaca attaaatggt aagggtcgcc cttaccattt ataatatgga
    14281 atagaataag taggaggaaa cttaaaaaat ggctaatata actgctcaaa tggtaaaaga
    14341 gttaagagaa agtacaggcg caggaatgat ggactgcaag aaagctttac aagaagctga
    14401 aggaaacatg gaaaaagcag tagatttatt aagagaaaaa ggattatcaa aagctgctaa
    14461 aaaagctggt agagttgctg ctgaaggtct agttgcaata gaaatgaatg atgataatac
    14521 agttgcttct atggtagaag ttaactcaga gacagatttc gttgctaaaa acgaagactt
    14581 caaagtgttc gttaaagatg ctgcttgtat ggcattagct actgataaag aagatatagc
    14641 ttctttatta ggtgaaactc ataaagaggg aataacttta caagaagttt taaataatag
    14701 agttgcaaaa ataggtgaga aattagactt tagaagattt gctaaagttg taactaatgg
    14761 acaagttgct ggatacattc acggtggtgg aaaaataggt gttcttgttg aaatggaaac
    14821 agaagctaga gatgctaaag ttttagaatt aggtaaagat gtagctatgc aagttgctgc
    14881 tatgaatcct aagtatgttt caagagatga agtagatgct gaatacatag cacatgaaac
    14941 agaagtatta actcaacaag ctttaaatga aggaaaacca gctaatatag ttgaaaaaat
    15001 ggttaaagga agattagaaa aagaattaaa agaggtttgt ttattagagc aaactttcgt
    15061 taaaaatcca gatataactg ttaaacaatt agttgctgat gttgctaagg cagtaggttc
    15121 tgatataaaa gttgttaaag ttgtgagatt cgaagttggt gaaggtatac aaaagagaga
    15181 agaaaacttt gcagaagaag ttgctaagca acttaagtaa taaccaaaga gagaacacgc
    15241 aggtgttctc ttttttaaaa aatagaaaaa attggatatg aaggattgaa ataggaggtt
    15301 tctgatggat aaaccaatgt acaaaagggt attgttaaaa ttaagtggag aagcattagc
    15361 aggagaaaga ggttttggta taaataatga tgtagttaat gatattgcta ttgctataaa
    15421 aaaaatacaa gaaataggtg ttgaagtagc tgtagtagta ggtggaggaa acttctggag
    15481 aggcagaacc agtgaaggaa tggacagaac tactgctgac tatataggaa tgttagctac
    15541 agttatgaat gcaatggcgc tacaggatgc actagaaaat atagatgttg ctacaagagt
    15601 tcaaactgct atagacatga gacaaattgc agaaccatat ataagaagaa gagcagttag
    15661 acacttagaa aaggaaagag ttgttatatt tggtgcagga acaggaaacc cttactttac
    15721 aacagataca actgctgctt tacgtgctgc tgagatggaa gcagaagtta tattgttagc
    15781 taaaaatgtt gatgcagtat atgacaagga tccaaaagta catgcagatg ctaagaaatt
    15841 tacagaatta agttacatgg aagttataca gaaagaatta aaagtaatgg attctacagc
    15901 tacatcttta tgtatggata ataaaattcc aataaaggta tttgagctta caacagagaa
    15961 tataataaga gcagtaaaag gcgaaaatat aggaactact gtaaaataat gaagaatgaa
    16021 ggaggagtaa aattatgaaa ctggaaatac ataagcaatt agaagagaaa atgaatggga
    16081 caattgatgc tttaaagttt gaatttggaa ctataagagc aggaagagct aatgcacaaa
    16141 tgctagacaa aataagagtt gattattatg gaactccaac tccaataaat caaataggtg
    16201 ctatatctgt accagaacca agaatattaa tgatatctcc ttgggataaa tctgctatgc
    16261 atgaaataga aaaagcgata gctaactcag acttaggatt aaatccatca aatgatggtg
    16321 aggttataag actttctgta cctgctttaa cagaagaaag aagaaaagaa ttagctaaaa
    16381 aagctagtaa agctgcagaa gaatttaaag ttagaataag aaatgaaaga agagacgcca
    16441 atgagaaaat taaaaagatg gaaaaaggcg gagaattaac tgaagatgaa ttaaaaaaag
    16501 cacaagatga agttcaaaaa atgactgata aatttataaa agaaatagat gcattattat
    16561 ctaaaaaaga aaaggacata atggaggtat aatattgaaa aaatattata accttttagg
    16621 tcttcatgta gatgaggtaa aacaatattt tgatgagcaa aatataaatt ataccgtaaa
    16681 atctattgaa ggtaaaaagg ataaagaaaa acttgtagtt cctagagtta taaaaatatc
    16741 tgagataggt gatagtgtag aactgataat cacatacttt tctgactcct tagtttaagg
    16801 agtcagaaca atattggagg caaaatatga ataacaacat tatatatgat atagacttaa
    16861 ataacatacc tactcatatt gctattataa tggatggaaa tggaagatgg gcaaaagcta
    16921 gatttcttcc aagaactgca ggacataagg ctggagtaga aactataaga gatatagtaa
    16981 aagaatgctc aaaattaggt gttaagcact taacattata tgcattttca acagaaaact
    17041 ggaaaagacc gaaacttgaa gttgacacac ttatgaactt attatctaca tacttaagaa
    17101 atgaaatagc tgaacttcac caaaacaatg taaaagtaac tgctatagga gatataagtg
    17161 ctttaccaaa aacttgtata agagaattaa actcagctaa ggaactgaca aaaaacaata
    17221 caggagttaa cttaaattta gcattaaact acggaagtag agcagatata aaaaatgctc
    17281 ttatagatat agtaaaaaat tgtgaaagtg gtaaaataga tataaacaat attgatgaag
    17341 atattataaa aaactattta agcacaaagt ctataccaga tccagacttg gtaataagaa
    17401 caagtggtga acaaagattg agtaactttt tactttggga agttgcttat tctgagtttt
    17461 actttactga tatacattgg cctgatttta aaaaagaaga actacagaag gctatatacg
    17521 tatatcaaag aagggataga agatttggag gacttaagta aggagattat tttatgctta
    17581 caagaattat tgcttcacta gctctggttc cattatttct atttgttgta tatggaggta
    17641 ttcctctata tatagctgag acagcaatag tttatattgc attgcatgag ttttataagg
    17701 catttaaaat aaaagatgta catccaatat tcattatagg atatttattt tctatttatt
    17761 tagctgtaaa aaatattttt aatttaccat tagaatatac ttatgcagta atttttattt
    17821 tatttttagc aagtataatt tatatgttga tgggcaaaaa caatgttata gatgtttcga
    17881 ttacgttttt aggagttttt tatataggag tatttttaga ttttataatt ataactataa
    17941 atggatttga aaaaggtagt atatatgtat ggcttatatt tgtgatatct tttatgacag
    18001 atatatttgc atattttagt ggttatttac ttggaaaaca taagctaatt cctaaagtta
    18061 gtcctaaaaa gactatagaa ggagctattg gaggaataat aggaagtaca ctttgttgta
    18121 ttttatttgg atatttattt ggcattgatt tgcttcaatt agcgataata ggaagtatag
    18181 gaagtgtaat agctcaatta ggagatttat ttgcatcttc tataaagaga tatgtaggga
    18241 taaaggatta tggaaagata atacctggtc atgggggtat attagataga tttgatagtg
    18301 ttatattagt tgcacctttt gtatatagtg cgattaaatt ttttattaga taaagattgg
    18361 ttggatttaa aagagcaatc tataattgct agtaatgaaa atagctatgt aacttttaaa
    18421 tgcagagata ttctgcagtt attagttaca tggctatttt cattgttcaa aaatttagaa
    18481 gaccttgggg aattgtataa gaataggtat tactttataa tagtatacta tatttgtagt
    18541 gagtatattt tttatactgt aactatcatt aaaaaatatt tttttgttta ataatttcga
    18601 tatttttag
//
LOCUS       DAEPXW010000077        18597 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.078, whole genome shotgun sequence.
ACCESSION   DAEPXW010000077 DAEPXW010000000
VERSION     DAEPXW010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18597
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.078"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            511..1371
                     /locus_tag="KRM55_002655"
     CDS             511..1371
                     /locus_tag="KRM55_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1594878.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSE
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1361..3232
                     /locus_tag="KRM55_002656"
     CDS             1361..3232
                     /locus_tag="KRM55_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1594879.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASMLALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3252..4706
                     /locus_tag="KRM55_002657"
     CDS             3252..4706
                     /locus_tag="KRM55_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH1594880.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDKKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            5731..6939
                     /locus_tag="KRM55_002658"
     CDS             5731..6939
                     /locus_tag="KRM55_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594881.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMKIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            6970..8349
                     /locus_tag="KRM55_002659"
     CDS             6970..8349
                     /locus_tag="KRM55_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1594882.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMLENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            8455..9645
                     /locus_tag="KRM55_002660"
     CDS             8455..9645
                     /locus_tag="KRM55_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1594883.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGSVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9783..11111)
                     /locus_tag="KRM55_002661"
     CDS             complement(9783..11111)
                     /locus_tag="KRM55_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594884.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(11722..12936)
                     /locus_tag="KRM55_002662"
     CDS             complement(11722..12936)
                     /locus_tag="KRM55_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH1594885.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYKI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITNEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            13362..14078
                     /locus_tag="KRM55_002663"
     CDS             13362..14078
                     /locus_tag="KRM55_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBH1594886.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            14213..14839
                     /locus_tag="KRM55_002664"
     CDS             14213..14839
                     /locus_tag="KRM55_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1594887.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(15039..16583)
                     /locus_tag="KRM55_002665"
     CDS             complement(15039..16583)
                     /locus_tag="KRM55_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1594888.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLREAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(16609..17250)
                     /locus_tag="KRM55_002666"
     CDS             complement(16609..17250)
                     /locus_tag="KRM55_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBH1594889.1"
                     /translation="MKYLIDSANLDEIQKCFKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            17520..17711
                     /locus_tag="KRM55_002667"
                     /pseudo
     CDS             17520..17711
                     /locus_tag="KRM55_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            18351..>18597
                     /locus_tag="KRM55_002668"
     CDS             18351..>18597
                     /locus_tag="KRM55_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1594890.1"
                     /translation="MIAVKKAYKFRLYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNDKETFTYKQCSSDLTNLKKELNWLKEPDKFSLQNAL"
BASE COUNT         6917 a         2190 c         3058 g         6432 t
ORIGIN      
        1 atatattagt atatcttact agcatttaaa tgaaactaaa tttgaagctt tacctattaa
       61 tatatcttaa tagtgattaa ataaaactaa acttaagact ttatatgtta atatatctta
      121 agaatttatt tgttaacata cagttcatta tatttaaaag cattactatg ataattcata
      181 atagtaaaat agataatggt tcagacaata ttataaatat tagtgacggt aaaatagtat
      241 caatttagta tataaacctt gtcagataat cgcataacag agcttgtagt tatagaataa
      301 aaaaatatct aggaaaccgt tgacagattt atatggatag tataacatat agaatatgaa
      361 attaaacaaa aaagaatttt aattatggcg acgtagtcat aattttgagt atgttactga
      421 ttagcaggca gaactcaagt atatatgtga aaaatagagg gatactctat acatatatgc
      481 ttgagttctt tttattgaag ggaggaatat atgaaaataa ttcagatttt aaataataat
      541 gtagccttag taaaaagagg taaaaatgaa attattgtat ttgttaaagg aattggcttt
      601 aaaaaaagag tgggacaagt aataaatgaa aatgaaatag agagaacata tatactagat
      661 tcatacgata tgctagaaca ctttagttat ctactacaaa actcagactc caataatata
      721 gttcttatta atgaaataat tgaatatggt gagaaagctt taaatataaa gtcaagtgat
      781 tatctaagct taaccttact agaccatcta gagtttttac ttaaaagatg tgaaaagaat
      841 caatttataa aaagtccttt ggtatggaat gttaaaagat tttatccaaa gcattttgaa
      901 attggaatgc atgcactaaa attaattggt gatagtaagg gaattaatct tcctgatgat
      961 gaggcagtat caatagcact tcattttgta aatatggagg taaataaaga gtctcatgat
     1021 agtacaattg tagaattgag aactttagca gatatagttt ctataataaa atatcatttt
     1081 aatgtagagc tagatgaaac ttcaacaaat tatatgagat ttactactca tctacagtac
     1141 tttatccaaa gaattatgtc agaggaagct tcaatagatg aagataattc tatagattta
     1201 tataaacaag taagtcaact ttatccaaag tcatttggaa gtgttcaaaa gataagaaaa
     1261 tatataaaat cacaatttaa tgtcgatata tctataagtg aagaaactta tttaatgttg
     1321 catataaata gggtgactca aagactggag gcaaaatcag atgaaatata aagatttaaa
     1381 tgaaaatata ataaaactta tagggggaaa agaaaatata aagtcggtag cgcattgtgt
     1441 tactcgttta agatttactt taaatgatag gagtatcgct caaacagaag aaattaaaaa
     1501 attaaaagga gtaattgatg tagtttctaa tgatgttgct tatcaaatta taataggtac
     1561 tcatgttgta gatgtatata acgagtttat gtctatgata ggtttaagtt caagtgaatc
     1621 aagtataaaa agtgaaagaa aaaagggaat tagaggtatc aaaggtatat ttaattccat
     1681 ctttgtggta gtctcagaga ctatgacttc agtaattgaa gtactacttg cagctggtat
     1741 acttgcaagt atgttagcac ttttaaatat gtctggcata cttcagagtg acagtcctac
     1801 atatcaaata ttagatacat taagaagtgc tacatttcac ttcttaccag tattaattgc
     1861 aatagcatca gcaaaaagac ttaatgtaaa tccctatata gcagtagtgt tagcagttac
     1921 gttattatct tcatcaatag atggtgtaga aggattaagt ttatttggta taaatttaca
     1981 ggctacaact tatgcaaaca gttttattcc aatactttta ggagtatggg caatgggaat
     2041 tataattgaa ggtttgaaaa aaatattacc taaagcacta cactattttt tagttccagt
     2101 attatcttta ataataactc tatcagttac attaactgta tttggaccta ttggtatgtg
     2161 gattggtgat ggattaaact atgcatgtat gtttttaatt gatacattgg gtaattggag
     2221 tgttgttgca ctgtatgcag ctttacaacc actcttaata gtctttggtg cagcaaactt
     2281 tactatgcct atatctttaa attctgtgac aacattgggg tatgacccaa tttttatggg
     2341 cgctgcaaca atatctgata ttgcagtttg tggtgcaatg tttggatatt tcttaaaaac
     2401 taggaataaa gaacaaaaac aactatttgg tacagtaagt tttagtgcac ttatgggagt
     2461 tacagaacct tcagtgtttg gtgtgtttat gaaatataga agaccatttg tagcagtaat
     2521 gataggtgga ggtataggtg gtttaatagc aggtttagct caagttaaaa catatggaat
     2581 ggtttgggga ttagctgcat taccaacgta tcttgttgga ggagaggtat ctaactttac
     2641 atttatgata ataagtgtag tagtatcatt tgtagcagca acagcagctt cctatttact
     2701 aggaatacct tcagatgaaa aagaagaagt taagggtgat aatgaaaaag aattagaact
     2761 aataatcaac gagaacaatt caagaactat tagtattgga aatgttgcaa aaggtcaggt
     2821 aattgcactt ggggaagtta atgacaaagc attttcctct ggagcattag gtaaaggggt
     2881 tggagttata cctagtgaat caaaatcaac tgttatatct cctgtagatg gaactataac
     2941 tatagtattt ccaactaaac atgcatatgg tatagtgact gatgaaggat tagaaatatt
     3001 aattcatatt gggatagata ctgtaaactt agatggaaaa ttctttgaaa gtcttgtaac
     3061 acaaaatcaa agggttaaaa aaggagatgc tttagcagta tttgaatctg ataaaattat
     3121 agaggaaggc tttgattcta ctataataac tgtagttaca aatactagcg attatttaga
     3181 tgtaatctca tcaaatgatg aatcagaaga attattaact gtaatagtat aaattttagg
     3241 agggaaaatt catgaatatt aaagatacat ttttctgggg aggaagtatt gcagcccatc
     3301 aatgtgaagg ttcatgggat agtgataaaa aaggacctgc aattatggat tttgtaacta
     3361 agggctctta tgaaacgcca agagtaatta ctgataaaat agaagaaaaa ttggattatc
     3421 catctcataa tggaatagat ttttataata gatataaaga agatatagct ttatttaaag
     3481 aaatgggatt tagtgcatta agaatatcta tagattggtc aagaattttt ccaaatggag
     3541 atgatgaaaa tcctaatgaa ttagggatta aatactatga aggtctgata gatacattaa
     3601 tagaaaataa tatagaacct attgtaacac tatatcattt tgaattacct atgaatttag
     3661 tacataaata tggttcatgg aataacagaa aacttataga tttgtattta aagtacagtg
     3721 agactgtaat aagaagattt gatgataagg taaagtactg ggttacattt aatgagatga
     3781 accatattga ccctcaaaca gagcactcgg atatttttac ttatatgata gcaggtatta
     3841 agtatagtga aatagaaaat aaggttcaaa cattggcaaa tgtagggtat aatatgactt
     3901 tggcgggtgt aaaggttgca aagttggcta gagaaatcaa tcccaacaat aaagttggat
     3961 gtgtatttgg actaaatcca atttatccat acaattgtaa tcctagtaat gtgttaaatg
     4021 catttttaga taatgaccgt gattattatc aaattgatgc aatgtgcaat gggaagtttc
     4081 cacaatataa attaaaagaa tatgaaaaaa ataatataac tattgaagtg actgatgaag
     4141 acaaaaaagc atttaaagaa ggtaagttag attttatagg acttaattat tatttttcaa
     4201 gtgtatctac tccaaaagaa aatttatcag gtgataaatc tttatttggt gggattcaaa
     4261 atccatattt ggaacaaagt aagtgggggt gggcaataga ccctataggt ttaagattta
     4321 ccttgaacta tatttacaga aagtatcaat tacctatctt aattacagaa aatggtttag
     4381 gggcatatga taaaatcgaa gaagatggaa ctataaatga tgattataga attgaatatt
     4441 taagtaagca tctatctcaa atgaagtctg caattgaaga ggataatgtt gaatgttttg
     4501 gatatttgat gtggggacca attgatttag tcagtgcaac tacaggtcag atgagtaaga
     4561 gatatggatt tatctatgtt gacttagatg atgaaggcaa aggaagtttt aagagatata
     4621 agaaaaaatc atttgattgg tacaaagaag taataaaatc taatggagaa gttttagatt
     4681 tttctacgga tatagtagta gggtaggaat aagataaata gaagttagga actaatgtta
     4741 attagtgtct agtaaagcat ttaaaataga gtatagggtc tttaaagtaa agtgtgtatt
     4801 cttcttaaaa gtaatggcaa ctaaaattac tataaaaagg agaatacaca ttttttatgt
     4861 ttatacttaa gtaaatattt agacatattc atagtataat ttactcatta tataaaaata
     4921 gtatgattta ctcactatat aactttataa attttctgga aaaatgtcag aatatattga
     4981 caaagaaaag atttaaaatt ataatctata ttaagaatag tttgacaata taaaaacaag
     5041 tatttttata aatagtgaaa ttatttttat tgtaaattta agaataattt aggactacta
     5101 taaagataaa ggtatagatg tcattatatg ataaatcata cttgtataga aagaatttta
     5161 aagtatggct tatcattgat ttaatataat aaataatttt tgtttctagt aatagttcct
     5221 aggaataaga tatctaaatt cgtttagaaa tagtctaatt tacaaaggag gggatgcact
     5281 aatagataaa atttctatat aaagaagact taaagtgaag tatattctga taatattggt
     5341 ttaatgggta tattattatt tcgttttaga tattttaaga ataatttaag acgtttataa
     5401 aaatgtattc tatatctaat atttaaataa atataagtct tccaacatgt atactaatat
     5461 agagagtagt tgaagtacaa ttctaactcg taaaattatg tagaaagtaa aaatcaaaaa
     5521 gaaatctagt aagttgataa ctatagttaa tatttagaga gttaactcta gttatattta
     5581 tttagatatt ttaggaataa tttaggacgc atataatatc atcaaaaaat atcaagctat
     5641 accatatgta gttaagaata actgcataat atacatttta taattattgt tttattgata
     5701 aaaaattatt atatttagga ggaaacaaca atggaaaatt tttggaatcc acttacttgc
     5761 tttactgtat gtgtaatgat ttatgctttt agtgagtttt tatctaagaa aacaaaaggt
     5821 gcaatttcaa cattgttatt tgtatgtatt atatttttac taggattttg gacaaatatt
     5881 ttaccaaaag acattacagg agcatcaggg atattagctg caatgagcaa ctttggtata
     5941 gctttattaa taactaactt aggaacactt ataaatcttg aagacttatg tcatgaatgg
     6001 aaaacggttg taattgcatt agtaggtatt gtaggaatag gggttggctg tttaacagtg
     6061 ggtagtatgt tatttggtag agagtatgct ttaatagcag cacctccaat agcgggttct
     6121 actgttgctg gtattatcgt aacaactgtt gcagaagctg caaatagacc tgaacttgct
     6181 gcatttgtaa ttctagtatt atcatttcaa aagttctttg gcattccgat aactacatat
     6241 tgtataaata aagaattaaa atttaaaaga gataatgggg attttttgaa agatgagtca
     6301 aaaagtaatt ttaaacttcc aagtatgaaa atttttaaag aagatttagg taaaaaatca
     6361 tctactttag tgtatcttgc aaagctttca tttgttgcta tgattggtaa ttttgtagga
     6421 ttggctactt taataccagg atttacccct gcaaactatt atttaaatcc taatatagca
     6481 tgtttgttag tagggttgat ttttacacga ataggttttt tagaaaaagg aattttagat
     6541 aaatctcaat ctaatggaat tataatgttt ggttgtatgt tgatgttacc tggaggactt
     6601 gctaaggtaa ctccaacagc attgtttggg atgattgttc caactatagg aatacttgtt
     6661 gtaggctctg tatttataat attatttact gcaattgtag gaaaactatt gggatattct
     6721 ccaagaatgt cagctgcaat tggtgtaact tgtatgctag cttatcctgc aacacagata
     6781 atttccaacg aaggtattga tgctatggaa ggaactgaag aagaaaaaca aagggcaaca
     6841 gattatttat taccaaagat gattatagga ggatttgtta ctgtaaccat tgcatcagtg
     6901 gcatttgcta gtataatagg tccaattata tttggttgat agtaaataga tttataggag
     6961 gaatagaaaa tgataggaag tatatctata aatgagatag ataaaaaaag attcaaactt
     7021 gatgatttaa gtaagaaaat atgggaaaat ccagaaaaag catttaaaga atttaaagca
     7081 tgtgaaaata cagcaaactt tctaagaagt gaaggatttg atgtggaagt aggtgtagga
     7141 ggtttagcca cggctattag agctagtttt ggttcaggta aaccagttat aggttttatg
     7201 ggagagtttg atgcattacc tggtttaaat caaaaagttt caacaaagca agaagcattt
     7261 gaattgggtg catatggtca tggatgtggg cataatttat tatgtacagc acatgtaggg
     7321 gcagtagtag gacttaaaag agagatgcta gaaaataact taagtgggac tatagtattt
     7381 tatgcatgtc caggagaaga acaattaaca ggtaaaggat ttatggctag aggtggagca
     7441 tttgaagggt tagacttagc tataaatttt catccaaata aaattagtga agctacaatt
     7501 ggtacttcaa cagctgttaa ttctgtaaaa tttcatttta agggaaagac tgcacatgca
     7561 gggtcagacc ctcaaaatgg aagaagtgca ctagatgctg tggaacttac taatgtggga
     7621 gctaattatt tgagagaaca tgttacttct gatgtaagga ttcattatac aattacagat
     7681 ggaggagtag cacccaacat agttcctgat aaagcatcag tatggtatta tacaagagct
     7741 ttaagtagag aagctgtaga aagtacatat gaaagacttg taaaggtagc aaaaggagct
     7801 gcaatgatga ctgaaactga agttgaagta gagtttttag gaggatgtta taatacttta
     7861 aacaatcatg ttttagcaaa tcttgtatca gaatgtatga atgagattaa acaagagcct
     7921 tggactcgag aggaattgga ttttgcagct gaattagata gacaaagccc acaacaatat
     7981 aaggctatga taagtaaata taatttgcca gaaggaactc atctatatta tggtggagga
     8041 aatgttacaa actttaatag ttatggctct actgatattg gagatgtaat gcatatagtt
     8101 ccgacagcat acttttttac agggtgtacg aatctaggag caccaggtca tagctggcag
     8161 tttacatctt gtgcaggaag ttctatagga gaaaaaggta tgatatatgc atcaaagatt
     8221 atggctatgt ttggagctaa aatattaaat aatccagaga tagctaaaaa ggcaaaagaa
     8281 gaatttgata aatctatgaa tggtaaaaca tataaatgtc ctattccaga tgatattcca
     8341 actccttaaa aagacatgaa atttaatata taaaattata atttttatat cagcatcatt
     8401 tcattactaa aagaaagtga gattttgctg actatctgat taggaggaag gaatatgaaa
     8461 aattttttta aagaagcgca gtcaatagaa ggggaaatta ttagatggag aaggtattta
     8521 catgaaaatc ccgaaattgg ttgcaatcta ccgaaaacag taacctttgt taccagtact
     8581 ttagaaaaaa tgggatattc tccgaaattg acgtctaata atggaatagt agctgtttta
     8641 gacagtgaaa atggtggaaa gaccttatta ttaagggcag atatggatgc acttcctatt
     8701 atggaggaga cggatttacc ttttaaaagt aagaataaag atgcatctca tagttgtgga
     8761 cacgataatc acacagcaat gctcttagga gcagctaaaa tacttatgga taataagcac
     8821 ttacttaaag gtagagtaaa gtttgtattt gaaccagatg aagagactac cagaggtgca
     8881 aaatcaatga ttgatgatgg tatattagaa aatcctcagg tcgatgcagc tatggcattt
     8941 cacagtatgg tgggtaaatt tcttaacaca ggtcaagtag cttattcacg tggtccagct
     9001 atggcatctg cggatatatt tgaaataaca gtagaaggaa aagcaactca tggagcaagc
     9061 cctgaatttg gagtggaccc aataaacata atgtcgcata tacaaatagc attaaacact
     9121 atactttcaa gagaaaaacc tcagaaagaa cctgtagttt taactattgg tatgtttaat
     9181 gcaggaagcg taccaaatgc tataccaaat aaagcatcta tgtcaggtac tttaagaaca
     9241 tttgaccaat ttgttagaga aaaattaaaa aatagaatta ttgaaatatc tacaggaata
     9301 gctaaatcat ttggaggaaa tgctaaagtg gaatttaaaa tggggactcc tgcagttata
     9361 aatgatttgg atgtaggaga tgagattgta tcttatgtta aagaagttat aggaaatgaa
     9421 aatgtaatag actttccatc tgcaatgggt tcagaagatt tttcagagat tttactaagg
     9481 gttccaggag tatttttatg gattggaatg ggaagtatta gtcagggata taattttggt
     9541 atgcataatc ctaaagcaat ttttaatgaa gagggattag tttatggttc agctttattt
     9601 gctcattgtg cagtaaaatg gttagaaaat aattttagta gataataaca taaaatatta
     9661 ttaaatatta ttaaatatca taaaaggtat atcttaaaaa gatgcaaaga tatacctttt
     9721 agaaagtcat atataatttt acttaatatt agatgataaa atatttttat gcattttgga
     9781 ttttaatatt tattttctga tataaataat ttgtataccc tttcaggtct accttttgtt
     9841 gagttttgtt tttcatataa tatagtagcg tttccagact ttaagagact acttagaaat
     9901 ctattagcag ttctaactgt tacatttaaa catgaagata attccttagg agtaacttca
     9961 tctctttgta gaatttcagt aacagatata atcttttgaa tagtaagagt agacaattta
    10021 gaacttttgg caattgtatt tatatgtgga gttactttat ttgaaacagt aagtaactta
    10081 tcacacagta aaggtcctat tgtctcataa ttttcgttaa ctaagaaact gtaatttaaa
    10141 ggatttattt tagattcctt attagcactt atggcactag acatagcttg ctttatatca
    10201 ttaccaattc catatccaac acatacttta atatttgtac tattttcaat agattctttt
    10261 atataacatg cagtaaaatt tttagttaat gatttaatcg tttcacattt agtgaaaatt
    10321 ttaaaagaat tactattttt ttcaattata aaatcggtta atttatcttt tttaatacta
    10381 tttaatattt tataaacttg gtctagagta gagtcatcat aatttgtatc tttaactgtt
    10441 atatatatta cacttggttg atttcccttc attctatgta aatgaatatc ttttattaag
    10501 ttattaaaag tattttttaa taaatctata tcagggtata tgaaatgaaa gtttactcct
    10561 gcattttgta acataggaac aatactacta aaacgagtag tagaaaaatc gattttccct
    10621 tcattccata gattaatatg tttttttgca atcttttttt caagttttgc tatgtcagat
    10681 aaactcattt tagatgcatt ttcatcaata ctatccatta agtctccaaa tgtgccattt
    10741 gataaataat atgatatatc ttttggatta tctgcccagt ctgttaagtc aaagtacgct
    10801 ctagaaaaat ctaatgtatt atatttaaag ataagcttta gaaacatatc atagtaactt
    10861 tgtaagtcag taccaaaatc aactagaggt tttttaatag ttccagcctt ttttgtaata
    10921 gcttttttgg gaatggggcc actaactgca aatccatcaa acctatcttc tatttctaaa
    10981 tataaatctc caacatgaga aaaatctcta tagatatata tttcaatttc tgcattaata
    11041 tttaactttt ttatagaatt atctacaaac tcttttaaaa attcggttgt tatgactgct
    11101 attttcatca tagattactt ccttttcaat tattataatt attttatatt aaatattaca
    11161 ttaatctatt gttctagtta aaatcttatt tcaattaaat tcaattaaaa taaataactc
    11221 tttataaaaa gcaattattt aggtagagga atatttgcta actttaatag tctttgttaa
    11281 ctttaatttt atttaagtta ttatagtctt actaatttta taattgtaga tttaactact
    11341 ttatgttctt ttattgttta tgtagttgat ttagaagtta ttttaaccat ttattttaat
    11401 tgaagttgtt tgatttttaa atcctttgtg taatctttgt ttttctagcc atgataaaag
    11461 tatttctatt tgtatcacta tatataataa tatcatgaca aaatatttat tgtctaacta
    11521 attataatct atccaaaatg aaaatgggtg tgagatatta ttacaacaaa ttgtattagt
    11581 attaaacaaa attaaaaaac taaacagtta aataattaaa cgattaagtg actgtcatat
    11641 aacaatttat aattttattt aacagccact taggtattta agagcgatag aattgagtgt
    11701 atatcaaatt ataataattt cctagtaaat aattgaaaaa taaggtagtc catttttata
    11761 tttgatatct ggtttacctt gaataagtgg atatagataa tttagggctt cattagttat
    11821 ataattacat tcttcattta tccactcttt aggaaaatat tttgtcttgt tagctatttt
    11881 agaaatatca gtatgactaa cttcatactt ataaggatta ttgcatgttc tattaatgat
    11941 agccataact cctgtatatc cttttttaga tagttctatc ccatatgcac caacttcagc
    12001 tgcttgtttt aaatcagtat ctgaagctaa atgcatagca catctttgta ttacaccaag
    12061 ttctaaggtt tttactcttg ttgtaattga tgatgatact ataagattct ttagatagtt
    12121 gcttactcca cctaattggg aatgaccaaa tttatcatga gcagaagttt tttgttcgca
    12181 tataaagttg ccgtatttat cccttatacc ttctgatgca actatataag ccttattttt
    12241 ttctttaaat atttttctaa catcttctat aaacttatct tcatagaaat caatttctgg
    12301 aaggtatatt aaatcaacaa gtggagtatc attaagtcta gctagtgaag aagaagctgc
    12361 taaccatcca gtatctctac ccatagtttc tactataaat ataccattat ttttgtatat
    12421 agaaaaatct aagtatgttt ccattattag tgtagaaata agctttgcag cagaaccaaa
    12481 tccaggacag ttgtcagttc ctaataaatc attatctatt gttttaggaa tacctataaa
    12541 ttttatttta caagtagtgt ttttgcagta ttgagaaaat ttcatcactg tgtccataga
    12601 atcatttccg cctatataaa ataatgtatc tattttatat tcatctagta tatttataac
    12661 tctatcataa tcataagaat ttattttata atcagccagt ttgtatctac aagaaccaag
    12721 accagacgaa ggtgtttgct ttaaatttaa tacattatct ttgtttaagg agtctgaatc
    12781 tattatattt ttgtttaata taccttcaat cccattgata ccaaaatata ctttatcaaa
    12841 gtatttagtt tctaaatttt tttcataaat accaactgca gaagcattga taacagctgt
    12901 agggcctcca gattgggcaa taatacagtt tctcatttta catctccctt tcattaatat
    12961 tgttatgaat ggtacttttt atcgagtaaa tttatattta tagtctgatt atatattaaa
    13021 tgaactagct atatcaattg agttagtata gacaataaat gccataagaa tgtggtaaaa
    13081 aactaacttt ttatatacaa ttaatgtcta taatttacca caatataaag gtacttttaa
    13141 ggagtagtca aagtgttgtg aaaaaaaata tatcagtgta atattaattt acaaagcaaa
    13201 ataagttcac agttaacaaa agcagaataa gttcataaaa gaaatatata cagcaataaa
    13261 agtaatgcta aataaaagta atactggatt aaaaaatatt aaaaaaatat caaaaactaa
    13321 tatttaatac taattaaagt aaaatatgga ggtatacaaa tatgaaacac ataaaaatag
    13381 cagcaggatt agcacatgta aattacggtc atatatcagc cgtagttaaa gaagcaatgg
    13441 atgcaggtgt agattacgta cattcagatg cagcagatat gcatgactta aaaaatatgc
    13501 aacttatggg tggtcatcaa ataatagaag caataagacc agtgacagat aaaccaatag
    13561 aatgccatat atacacaaga gattgtgata gattatttat agaaaaaata gcagcagcag
    13621 gatgtaactt gttgataata ccagcagaac attttttagg tgctcctctt gcatacataa
    13681 taaattactg tagagaattt ggtatgaaag taggattaac aattggatgt tacacaccat
    13741 tatgttttgt tgatgaagct atatatgata tagatagatt gcaaatagtc gttcatggtg
    13801 ttgatgaaac tgatggaaaa gataactggg gatggagaaa gagtgctgtt gatttagtaa
    13861 aaagagctag aaaaatgata gacgaaaaga atcctaagtg tgaattagca atagatggtg
    13921 gactaagagc agacaatatg gagccattaa tagaatgtaa cccagacgtt gtaatattat
    13981 cttcagcaat attcaaggat aaagatggta taacagcagg tgttaagaat tgtagaaaag
    14041 ctatagatga agcagctaca aagtttggtt tagaataaga taataaacta tgataaaaga
    14101 gatgctttct taatgtttta aggaagcatt aattttatga aaaactacag gaagctagac
    14161 taatttaatt gattttttat actgaaacaa tataatcata ggaggttatt aaatgaaaaa
    14221 agaaatgata aaagattatt tactgataac aatatcagca tttttaatgg cattagcagt
    14281 taattttttc tttgcagaac atacattagc tccaggaggt ataacaggat tatcagtcgt
    14341 acttagcaca ttcttatcaa tgcctgttga gaatatatca ttaggaatat ctatgccact
    14401 tttagtaatg ggattattat ttttagggaa aggttttgga ataaaaacat tatatataac
    14461 tcttatgggt ccattattct taaaagtaat accacaaact cacataactg acaatctatt
    14521 agtagcagga gtgataggtg ggttattggt aggaactgct atagggatag caataataag
    14581 gggctgtagt actggtggaa ctgatttagt tgcaatgctt attaataagg taattaagtt
    14641 tctgaagttg ccagttatat tatttatgct agatggattt ataatagtag cgtctggaat
    14701 aataagtaag aattttatga tatctatata ttcattgata tccttattac tcataataaa
    14761 aacaatagga tttgtaacta caaagtttgg taagaatact gaagaaatta ataatataaa
    14821 taatgcttgt gctcaataaa aataataaaa tttactttaa atataaaagt ttaaaaaata
    14881 taaaagctta aataaaaaga ttaaatataa aaaatgaagg tgtctcaaaa tgaatttttt
    14941 agttcatgag gcactttttc tatgaaatca aatatatttt tatcatttgg acaatgaaaa
    15001 ataggtttat ctctatgttg agacaagcct atttttgttt atttataaga taatatttta
    15061 tttttttcag aatatagttt ttttataatt gtactaagtc tagaaatatc attcttactt
    15121 aaaagagcat ttatatttat cagttcagca ttatgttcaa agtctacagg agcagtggtt
    15181 agtattaagt ccacatcatc aaagttcgta aatgaaatag aagatagagg tatagattta
    15241 actatattaa tctgattaaa ttcaaaactt aacttttgga ctaataaatt agatacacca
    15301 tcactacagt gacatattaa aatagtattt aggggagatt tgcttctatc tattgctgat
    15361 attaaatata aagcaagata tcctatttcg tcatcattga cttcataatt catcaactgt
    15421 ttgataacag tattagactc tttagcagcc ttataagtat aaggaaatgt tctctttata
    15481 tcatttaata tgggatttgt aatagtaaac ccatagttta ttctgtgtag aactgattta
    15541 aggtgattag caagagactt tattaatatt aaatcatcct ttaagtttaa gtttagtata
    15601 cttccccaat gaacagctat tgcttcagat agattatact ctgtaatttc ttcattttta
    15661 agaggttcaa gagtagtagt tttctttatt gatttaagta atccttctat atgaagaagg
    15721 atataacaga cctcttcatc aataaattct acgtcaaaag cttctcttag gttagcacat
    15781 aaaatttttg atttttcaaa gtattcatgt tctaataatt ctctaaaaaa accttcagat
    15841 aagttaatat atcttttaat tgaaattctt ttaatacata tagctatatg tattaagaag
    15901 tttatataat actcatcact aaggttactt ttttctactt gtaaggtgtg tagagtgatt
    15961 tgagataatt tctcaaaatc atagttaaat agttccttaa atatttttgt tgatggggta
    16021 tctttgcatt cattagattt cgagaataat atttctttaa gttcagtata acttttatta
    16081 accgtagcaa gttcaaaaat tgcttttcga atatctttct cttttccctc taaatatact
    16141 ccattattgg tttttctaac tagagtcact ttaaagtttt gcaaaaaatt ttgaataact
    16201 accaagtctt tatgcacagt agctctacta acatgtagtt cattgcaaat atcacgaatc
    16261 ctaaacttag aatttttaat aaataattta cttagaatat acctttttct atcttcagga
    16321 gagtatgcat atatacaatt tgatttatca ttgatatctc taataacttt aagttttata
    16381 tcttcattac ctagaataat aacccctgaa ccagtttttt tatctaggga taaattaaac
    16441 tctaaaagcc attcatctaa aataacaagg tcattacgaa tagttttatt actaactttt
    16501 aattcttcgg caatagtatc tacagtaata tagtctgagc tgttgagtaa taattcagca
    16561 atatctaata atcttttgtt caatgcaaac cctcctaaat cttagttact atttattaac
    16621 cttggaccaa tctctttcaa aagtattggc accatctatt gtgagctggt taaaagaagc
    16681 ttttttaaat aaatcatatg ttacagctgc ataatcacat ccacaaagag atgcttgagt
    16741 taagtggaat acatttttaa tagaagctgc aacaacttta gtattatatc catttattga
    16801 tataaggtta catatttctg taaggttttt tataccatca ttcccatttt catcatttct
    16861 acctataaaa gggaataggt aatcagcacc tgcatttata gctaatgatg cttgatttac
    16921 attgaaaatc aaggtacatg cagtttttac acctttacta tttaatatgt ttataagttc
    16981 taagccaact tcagagaaat ttatttttat tatagtgttt ttatttatat ttaatatctt
    17041 atcacatgaa ttaattaatt cgtataaatt atttccaatg acttcagcag ttaatatttc
    17101 tggatttaaa ttagcacatg tctcaataaa ttcatggaag tttactttct ctttaagata
    17161 catagatgga ttagctgtta ttcccttaaa tccatactta aaacactttt gaatttcatc
    17221 aagattagca ctgtctatca aatatttcat aatttaattc tcctttaagc tatttgtcat
    17281 aaaaaagtgt atatactcta tttttattat taagtcaatt atacaataag attgattata
    17341 aaattataac atgggtactt aataaaattt acataatgat atggtaataa taaaacattt
    17401 attgtctaat aattgccata agctttagta aataagagtt aacagtgaag gtattgcctt
    17461 aaaaatccta tgatatgtat aatttgaata tgaaggcaat aatttaaggg aggaaaaata
    17521 tgattaactt ttatcaacca tcaagaataa attttggaca aggaacttta agtgaattac
    17581 ctagaataat aggaaaatat ggaaagaaat gtttgttagt tactactcca aatgtagagc
    17641 cattagacaa gttatataaa agagttacat tgaatttaat agaaaaaggt atagaagttg
    17701 tacactttga ttaaaaaata gctacgcaca ctcgtgactt tagtcatgag ttaatagcta
    17761 aaatagtcag catataggga aacctatatg tagagatagg atagaaccta tccaatacta
    17821 cttgaattgc tggaaacccc taaagctaac caaactaaaa cataaggatg aaataaacct
    17881 aagtgtgaaa gttacgaaag tagaaaaaat tggttagatg gtataaggtt aaatcctaag
    17941 tactttaaaa tgggcaatca gcaggtaaac tccgaatagg agaaacttca acgactattc
    18001 ctcttgaggg aagtacacta caagttatcg gtagtggaag tgggtagacc ttaacggata
    18061 atgccgaagg ataagatata gtctgtgctt gcatgaaagt gtaagaagtt cataagagaa
    18121 ctgcataggt agtagcgaac ttatgtgaac gacaacctca aaaatgataa aagttaagac
    18181 ttacggttct taaatatgtt atttaaaatt aaatataaaa ccttctaaat aattgtttta
    18241 aataattaca tttgttaata ttatgatagg tggttaataa attgttcacc acagcattat
    18301 ataatatatt aaaatcatta aaaagtgtat caaaaaacaa ttaaagtgag gtgatagcag
    18361 tgaaaaaagc ttataagttt agactgtatc caaataaaaa acaacaagag ttaattaaca
    18421 aaacttttgg atgttgtaga tttgtatata ataagtatct tgctaaaaga atagaagttt
    18481 ataaaaacga taaagaaact tttacttata aacagtgtag ttctgattta accaatttaa
    18541 aaaaagaatt aaattggctt aaagaacctg acaaattttc actacaaaac gccttaa
//
LOCUS       DAEPXW010000078        18534 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.079, whole genome shotgun sequence.
ACCESSION   DAEPXW010000078 DAEPXW010000000
VERSION     DAEPXW010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18534
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.079"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            487..1530
                     /locus_tag="KRM55_002669"
     CDS             487..1530
                     /locus_tag="KRM55_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594891.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VEGEKIDLNKFEGLDQNENYNLEKNVIEEKEVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            1641..2783
                     /locus_tag="KRM55_002670"
     CDS             1641..2783
                     /locus_tag="KRM55_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1594892.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            3237..4628
                     /locus_tag="KRM55_002671"
     CDS             3237..4628
                     /locus_tag="KRM55_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH1594893.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            4881..6674
                     /locus_tag="KRM55_002672"
     CDS             4881..6674
                     /locus_tag="KRM55_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1594894.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKSIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(6755..8137)
                     /locus_tag="KRM55_002673"
     CDS             complement(6755..8137)
                     /locus_tag="KRM55_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH1594895.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPINGRESIRKSLEYKKMLASRPLTLIEKKRIVVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            8395..8742
                     /locus_tag="KRM55_002674"
     CDS             8395..8742
                     /locus_tag="KRM55_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1594896.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            8760..9794
                     /locus_tag="KRM55_002675"
     CDS             8760..9794
                     /locus_tag="KRM55_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594897.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(9843..10892)
                     /locus_tag="KRM55_002676"
     CDS             complement(9843..10892)
                     /locus_tag="KRM55_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1594898.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            11167..12702
                     /locus_tag="KRM55_002677"
     CDS             11167..12702
                     /locus_tag="KRM55_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594899.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(12887..13573)
                     /locus_tag="KRM55_002678"
     CDS             complement(12887..13573)
                     /locus_tag="KRM55_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBH1594900.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            13702..15084
                     /locus_tag="KRM55_002679"
     CDS             13702..15084
                     /locus_tag="KRM55_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1594901.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            15486..16754
                     /gene="eam"
                     /locus_tag="KRM55_002680"
     CDS             15486..16754
                     /gene="eam"
                     /locus_tag="KRM55_002680"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBH1594902.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(16847..17203)
                     /locus_tag="KRM55_002681"
     CDS             complement(16847..17203)
                     /locus_tag="KRM55_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594903.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(17354..18448)
                     /locus_tag="KRM55_002682"
     CDS             complement(17354..18448)
                     /locus_tag="KRM55_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1594904.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         7378 a         2156 c         3005 g         5995 t
ORIGIN      
        1 ttaatcatgt tgagtttcaa ggtctatatg attaattaaa tccatttttg ttatttataa
       61 ttattattga atatattttt acatataaga tataaggtga tagatagaaa ttgttggatt
      121 atgtaaataa ttaatatata ataccattat gggcaataaa tacaaatcaa atgataatat
      181 agtctattta tgtaaatgtt aaattgtatc ctaagtataa tagtaagttt tttgatagtg
      241 gtgtagaaag taaaaatcta ctagcctaaa ttgatgtatg gattagttta ggaacagtaa
      301 ttgcatatct taagtttgat gtcatgttgg gctactagaa ataggtcatc tttttcactt
      361 gaatatcttt tctttaaaca tggggagtat catatcaaaa acatatgaaa attaagtgat
      421 ttataagaac agtaatattt tatatgatag tatagaatag taataaagta ttaggaggaa
      481 cattgagtgt taaaaaagtg gtttggtatt gtgaaaaaaa gacaaaaaag tgagtcagta
      541 aaagaagaag gtgaagtaat attaaaaaac gaaaaaatat tatctgaaga aaagttgata
      601 gatgaagaag gagttgtagt taatattgat aatgaaatat taactaaagt agaagtagta
      661 aatgatgata atgaaataga agaaaaaata atagaagaag attggttaat tagtgaaaat
      721 accataaaat tagatgataa agaagcaatt attaatgata aaaacataga attatgtaaa
      781 aaagaagttc aagttgaagg tgaaaaaata gatttaaata agtttgaagg acttgaccaa
      841 aatgaaaatt ataatctaga aaaaaatgtt attgaagaaa aagaagtaag tgaatgtttg
      901 acagaagaag atttagagta cataaaagaa attaaaataa aaagaggaaa aagtataaaa
      961 gctataaact tgtatactaa agaagagtgg gtttttgaca ctcatataca gtgtagtaaa
     1021 aaactcaaag ttccattagg gtacataaga gaaaatttaa aatatggata tatggattac
     1081 tttggagatg caataaatta tttaagtgaa gtattaaata tagatgaata ctgcaaaagt
     1141 gaatggagct atctcgataa tagcaaatct ccatctgaga tatttaatat tctaaacaat
     1201 aaaatattta gtataaggct ttctaatgaa aaaagaaatg aaattttgac aaatgataaa
     1261 attgaagcat taaaaatgaa ttatagattt gaatgtattg atgaagaata tgatgaatat
     1321 tttaaaaaat ataagtctat aatcaaaaga ggtggaaaga aaaaagttga attagtaaat
     1381 aaaaaaggtg acattttaga aatatttaag tctttagaag aatgtgccat ttatttgcaa
     1441 aaggaaaaga atgaagttat acaaatgtta aaatatggag atacaaaagt aggaagaaac
     1501 tttataaggt atagtttgag aagtatttaa tttcatttta aattcataag agtttcattt
     1561 ctgattcaca catttaatat tattttaatg taaaataata aaggtgaagt attgtacaat
     1621 taaaattaag gagggtatta atgtctgaag aaaaaaatcc aaaagaaaat acattagatg
     1681 aatctaaaaa ttcagataat gtaaattcta aaaaagatga tgtgtcagat gaaaaaaata
     1741 ctgataacaa agttaaaaaa agggaaataa agctaaacaa caaaacactt aaagctattg
     1801 tagcaattgt tgcagtagga gctatatgtt taggtggagg ctatgttttt ggcaaagaag
     1861 ctggaagaaa attgcctgct acttcaaaac actataatag cagtgaggta gtagctacta
     1921 ttggggataa aaaaataaca ggtgaaatgt taagaaagag aatggagcca ttattttatt
     1981 taaatgcaaa aactactatg actgatgacg aaatacgttc atatgaatca aatatgattg
     2041 aaactatgat tacatctgat atattatcct ctgaagcagc aaaagagaaa ataagtataa
     2101 ctaatgacca actagatgct cagtataata atttaatgag tagtatagaa tcagcaatgg
     2161 gaatgactaa agaagagttt ttaaaacagt ttgatttgac tgaaaaatat ataaaagatg
     2221 atatgaaaaa agagctagta gcatcaaaat atttaaatga aaaatcaaaa gttactgata
     2281 aagaagcaga gaactattac aataaaaaca agagcaatta tttacaagtt agagcttcac
     2341 atattttaat aaaaactgtt gatgataaag gtaagcaagt tagtagtagc aaaaaagctg
     2401 aacttaagaa agaagctgaa gaaatactta aaaaagccca agctggggaa gattttgcta
     2461 ctctagctaa aaaatactct gaagatagta gtgcagaatc aggtggagat ttaggtttct
     2521 ttggtaaagg tcagatggtg gaatcttttg aaaaagcagc ctttgcattg aagaagggag
     2581 aggtatctaa caaacttgta gaaagtgatt atggatatca tataattaag aaaactgatg
     2641 aaaaatatca gccatttgaa gaggtaaaat cagatttagt aagcagttta acatcagaaa
     2701 aacaaaacct acttatacaa aatctaaaag aaaaatataa tgttaaaatt acagataaat
     2761 atcaaatgaa agctaaagaa tagataaagt caatttatta aaaaaaagaa aaattaactg
     2821 tatggataaa agctattttt actctcaata tagagagtat aaaatagctt ttattatttt
     2881 gcaataaaat ctatttatat atatgaagtg acaaagaaat aacatgcaaa aagatattaa
     2941 aaagaaatat ttttaatttg aattttttca ataaaaattt acaaaaatga aaaaataaac
     3001 aaaaaagaat tgaagattta agttgttatt taaatatata tatattaaga ttttctgctg
     3061 aagatactaa aaaaataata tttttcataa ttttaaaaat aataataaaa aaatgaaaat
     3121 acaggcgata atctattgag taaacataga aaagatgata ttataagtat gtgctaaaat
     3181 ggttaaagca atattaatat taaatttaac tataaaacaa aagggggcgt ttttttatgt
     3241 caagtacaga aagcgtatct aaaaaaagtg gtcatccgaa gagtttttgg cttatttgca
     3301 tgacaatttt gtgggaaaga tttagttatt atggtttaac agctttattg gtattatttt
     3361 ttacagcaag tgtagctcaa ggtggtttag gtctttctac tcaagaagca acatccatgt
     3421 ttggcttatt tacaggtctt atatatctta caccattagt cggtggctgg ttagcagata
     3481 aagttttagg tcaacaaaaa tgtatttcta taggtgcact tttaatagca ataggagatt
     3541 tcgtactatt tgcttcatct acatctattg caatggtttg ggtaggtcta tcaataatta
     3601 ttttaggaaa tggttttttt aaatcaagtt gctcaaatat agttggggat atatatccta
     3661 aaactgatgt gtcaagaaaa gatgcagcat acagtttatt ctatatggca gtaaatgtag
     3721 gagcatttat agctccaata atatgtggat tgctttctga taatgtattt gcagtaagag
     3781 gagcaagtgg agatatagta tcttatggat ataagatggc atttttaatt tgtggtatag
     3841 gcatgatgtt aggtatgatt atatttacac ttcttgcacc aaaattatta aatgaagtcg
     3901 gaaaatatcc tgtgactaaa ggtaataaag gtgaaaaaat tgagtatgga ccacttacta
     3961 agttggagaa aaataggata atagcaatgg ttattttatt tttatttgtg gtcttattct
     4021 ggacagcata ctatcaaaca caaagttctt ttatgattta tgtaagggat aatgtaaata
     4081 gaactctatt tggatttgaa atgccagtag catggcttac atcactaaat gctatattat
     4141 gtgtggcttt atgcccagta ttagctaccc tatgggttaa attatctcat accaaaagag
     4201 gtgatttctc tattccagtt aaaatgggat taggaatgat aataatgggt gttgggttta
     4261 tagttatggt atttgctaca ttagctaatg gtccagatgg aatggtaaag gctagtatat
     4321 tgtttatagt attgacttat atatttacaa cagtaggtga attattctta tctcctatag
     4381 gacttgcaat gttcaataaa ttagctccag ctaagtatgc tacgttgtct atgggagcct
     4441 ggtatctaac aagttttttt gcaagtttat tatcaggaaa gattgctggt tttacagcca
     4501 cacttggttt tttacagata tttggaggaa tagcaacagt tttaataata tttggtttaa
     4561 tattattggg aataagaaat gtattaacaa gattaatggc tatggattta ctaacaaaag
     4621 aaaaataatt catgacgaat tattgtaaat aaatgaatta ctttaaataa aggaagttac
     4681 atttaaatat aaaattaaat gtaatttcct ctttgattat gaaaaaaagc tttacacaaa
     4741 tagatattat aattaaaatt ataattgtga taattagagt gtataagatt tatataaatt
     4801 atacaaaaaa tatttatgta ataaacttta catacttata tatttagtta ttcaaactat
     4861 tatttcgagg aggtcttgtt gtgaatataa aagatagatt aagtggatta agaaaattta
     4921 tggaagaaaa aaatatagat gcctatatga ttccatcttc tgataatcac caaagtgaat
     4981 atgtaggaga ttacttcaaa tcaagagaat ttatatcagg gtttaatggt tcagcaggga
     5041 cggttattgt gactaaagac gaagctgggt tatggacaga tggaagatat tttatacagg
     5101 cagaatctca attagaagga agtacaataa aattattcaa aatgggacaa gaaggttgcc
     5161 caactacaga tgaatattta tacaaaaata ttcctgaagg aggaacttta ggatttgatg
     5221 gtagagttat atctgctaga gaaggagcta cattagctga aaaattatct aaaaaaagta
     5281 taaagataga atatcagtat gatttaatag atagtatatg gccagataga cctgctttat
     5341 cagatagtaa agcattttta ttagatgtta aatattgtgg agaaagtttt agctcaaaat
     5401 tagctagatt aagagaaaaa atgagtgaaa aaggtacttc tactcatgta ataactactc
     5461 ttgatgatat agcatggtta ttcaatataa gaggtggaga tgttaaatat aatccagttg
     5521 tactttctta tgcagtaata actttaaaag aagtttatct atttgttgat gaaagtaagt
     5581 taaatgaaga aatactaaat gaactagcta aggaaaatgt tcaaataaag ccatataatg
     5641 atgtgtatga atttgtaaaa aatatagaca aaactgaaaa agttttatta gatggaacta
     5701 agcttagtta tacaatttac aataatatac cttgtgaagt tgagaaagtt gatgagttca
     5761 atccagtaat gttttttaaa gctcaaaaaa atgaggtaga attagaaaat ataagaaatt
     5821 cacatgtaaa agatggtgta gctttcacta aatttatgta ctggttaaag aaaaatgtag
     5881 gtaagatgga aatcactgaa ataagtgcta ctcaaaaatt agaggactta agaagagagc
     5941 aagaaggttt ctttgagcca agtttcaata caattgctgc atataaagag catgctgcaa
     6001 tgatgcacta tagtgcaact ccagagtcaa attataaatt agaggcagaa ggattatttt
     6061 tagtagattc aggtggacaa tattatgatg gaactactga tataactagg actacagttt
     6121 taggacctat aagtgatgaa ttaaaactac actttacttc tgtagcaaga ggaatgataa
     6181 atctttctaa agctaagttc ttgcatggtt gtagaggata taacttagac atactatcta
     6241 gaagttgcat gtggaatatg ggaattgatt atcaatgtgg aactggacat ggtataggat
     6301 ttgtgctaaa tgttcacgaa gctccaaatg gatttagatg gagagtagta cctgaaagat
     6361 ttgatagtgc agttcttgaa gaaggaatgg taactactaa tgaaccaggt atatatatag
     6421 aaggttctca tggtataaga acagagaatg aaattgtagt tagaaaagct gaaaagaatt
     6481 tctatggtca atttatggaa tttgaagttg ttacgttagc tcctattgac ttagatggta
     6541 tagtaccaga attaatgaat aaggatgaaa aagattattt aaactggtat cataagttag
     6601 tttatgataa aatatcacct ttcttaactg atgaagaaag agaatggtta aaagtttaca
     6661 ctagagctat atagtttgta ctagatacaa taaaaatcga ggtattataa tgcctcgatt
     6721 ttttattgta tattttatta actttaaaaa atttttaatt tgataattct actaattttt
     6781 tattcattat aagtagtata attccaaata tcaataaaaa tgatggtatc actatgaaga
     6841 cttgtaacat accaagttgg tctataatag cttgcgtata gccagataat ttatttgctg
     6901 caaatttgcc taaaaaccaa acacccatta ggaatgaaat atacttttca ggcgaaagtt
     6961 tatttaccat accatacccg actggagaaa agcaaatttc tcctatactt tggaatgtta
     7021 aaaatccaac tacccaaaat acacttgctt tgtgaattga attagggtct gttcctgttt
     7081 gtataactgc tactatcata aacaaaaatg ctatggctaa tagtataaaa cctaagctca
     7141 ttttttttgg cacacttaaa tcgccttttt tagtttgaga taattttacc catactaaag
     7201 cagagatagg tccaagaata acacaaagga gaccattgta tgaatctatc catgaagtag
     7261 gaatttgaaa attgccaaca gtaagattta tgtgttcctt tgtatagagt gcaatagaca
     7321 tagaggcttg gttatatgct atccaaaaaa atactgtgaa aaaagctaac accaatatta
     7381 ctactattct ttttttctca atcaaagtta aaggtcttga agcgagcatt ttcttatatt
     7441 ctagtgattt tcttatagac tctctcccgt taatagggtc attattcaaa ggtttataaa
     7501 actttctgtt tccaaatata aagaagaata aacctattag aaccgtaatt gatgaaaata
     7561 aaaatacata tctatatcca tacatactta tagataatcc gcttttcata gcaaaccatt
     7621 cattagcaac taaaccgcat attaaagggc caaataaagt acctagatta gtagccatat
     7681 acgtaataga gaaagctcca tcttttcttg ggtcatcatt ggtatataag tttccaacca
     7741 tagtatgtaa gtttccttta taaaaaccta ttcctaatcc agataaaaat atcatgatgt
     7801 ttatatccat cttactattt gctatgtatc ctagaaaata accaattgaa accattagca
     7861 ttccaagtat aatacagttt ttgggaccta aaaatctatc actgacccat ccaccaataa
     7921 ctggagagaa ataagtccat gctaaaaaag atgcaagcat tgatgcggat tctgctggtg
     7981 ttaaccctaa accacctttg gagacttgtt cagctaaaaa caataataat accaatttca
     8041 taccatagta tgcaagtcct acaaaggtaa atattgaaca gcagaaatat aaatctctag
     8101 gttgtttaag tttttcttgc gtttttaaaa ctgacatatg tcgagaacct ccagataaat
     8161 agtttaacaa aattttacca tactatatga gtatatgttt ttttcatata gacgtcaact
     8221 tgtaagataa tttaattaag tcgaaatata tgtaaaaata gtatcatttt tgtgtattca
     8281 gtaatatttt tttatgataa tatatgttat tattatatta aaatataaac atatttatgg
     8341 aaaggatatg ccaatttagt agttagattg attgtttggc aggtgggatg agctatgata
     8401 agaaagaaat ctgaattaca agtagaagta aaagaaaatt taaatggtgg tataggaaag
     8461 gttaagcttg aaaacataat acaaaatgaa gagcttaaag gaaaaggaag actatttaaa
     8521 agagtagctt taccagtagg aagttcaatt ggtgtgcatg accatacaac agattttgaa
     8581 gtatattata tactaaaggg aaaaggtaaa gtatttgata atggggaatt tgtagaagta
     8641 aatgagggtg atgtagtgta tacagctgat ggcgaaaaac attctataga aaatatagga
     8701 gaagaagatc ttgagtttgt agcactagtt ttatatatgt aaaatatgga ggaggagtca
     8761 tgacaggcaa gatagaagaa attaaggaca agataaatag attttgcaac tccaatttaa
     8821 atcaagaata caaagatata agctttaaaa ttttgcaaaa ccttttagat aataataaag
     8881 agataattca ttcttctaga gctgatatat ggtcttcagc tatactaaat atagttttag
     8941 aacaaaatct tttatacaat aagaagcatc cactacatat aacaaaaaaa gagttttcaa
     9001 aacaaatagg tgtttcttta aatactataa ataataaatc gtctttaata aaagatgttt
     9061 gtagtattga ctttttaaat caagatacta tagctatttc taatgtagaa ttttgggtaa
     9121 aagagactaa ttccaaatca aagtctgtag atttagattt agaaaagaag aaaatactat
     9181 ataaaagata tattaagcta tcacaagatg cgaatagtga tattgaatca attagatata
     9241 tggaggaagc tgtaaatata ggtaaaagta tgattactaa agaagataaa gaacttggat
     9301 tttggaaagg tttatctacc agagcctata tgatagcact tgaatccctt gctagaaagt
     9361 tagaaagtat taataatcta aaggagtcca aaaaagtatt agaatattta atagaaatta
     9421 atcctagtga tgagcaggga ataagataca aattattaaa tgtattaatt agattaaatg
     9481 atagaacttc aataaataaa ttatttgaac tttataaaga agaaaaatct gctacatgga
     9541 tgtacagtaa agctctttat tactttaaaa ataaaagtat gtttttggca aatgattcta
     9601 ttaaggttgc tagaagtaaa aataagtacg ttggattata tttgttagat tggcgaaatg
     9661 cttttggtag agaatttgtt acagaggaag aaaaggcaga agctgtctat tactatgatg
     9721 aaaacatagt gatttggaat gaagttaaag gttctatgga ttggctatta aaaaaaatgt
     9781 tggaattttc ataaaaaaaa ctactcctta cttttatata agtcaaagga gtagttttta
     9841 atttatacat ctagttttaa atcttcaggt tttattagac ctttttttct cataaattct
     9901 gaaatcaaca aagttacaat agcaggaagt ataaaattaa gtaaaagtat accaacccac
     9961 atagatatac ctccttttcc agcactttgc atagcagtta ctgttccaaa ttgtccaacc
    10021 aatccacaag tacccatacc agaaccaata ggaatattct ccattttgaa tattgttgta
    10081 gataatggtc caagtaatat tgaagctaca gtaggtggta tccaaatttt ccaatttttt
    10141 attatattag gtacttgcaa catagatgtc ccaagacctt gtgccacaag gccaccaact
    10201 ccattttctc taaagctcat aacagcaaag cctaccattt ggcaacaaca acctacagtt
    10261 gctgcaccac cagcaagacc acctaaactt aacatcatac aaatagctgc actacttata
    10321 ggtaatgtaa gagctattcc aacaagtgca gagactaaag ctcccattat tataggttgc
    10381 atagttgtag cttgcattat tatatttcca aatgaagtca taaaagcaga aacagctgga
    10441 ccaataagtt cagctacaag tactccaatt agtattgtta cagcaggtgt aaccaatata
    10501 tctatttttg tttcttttga aactaatttt ccaacctcta cagcaaaaag tgtagcgaca
    10561 aatgctccaa caggtcctcc taattcatta ccacaagctc caacaagtgc acaagaaaat
    10621 agtacaagtg gaggtgcttg aagtccatac gcaatagcca ctgctatagc tggaccagta
    10681 acctgtttag caagagggct tataacttca gtaaaaagag aaatattgaa attatctcct
    10741 aatgtattga aaattgttcc aattaaaagg gacgaaaaaa gaccgagtgc catataactt
    10801 agtgcgtcaa taagatacct ttgaacagaa atttcaatat tttttctttt agcaaatgat
    10861 ttgaaatttc tttttttata attgatttcc aatttaaaat cctcctcata taatataagt
    10921 ataatttctt tttaattaat tatataactt ttcagctgac aagacaaatg ttatttcact
    10981 aaaattagac tattgtaata gtaagaaatt aacattaatt ttagttttaa attttaaatt
    11041 tatggtttat aattagtata gggatattct gaaatataat aattttccag tttatcccaa
    11101 catttaactt aggtagattg cttacaaaac aaatgattat atattaggct aaaaggaagt
    11161 ggatagatga tatttgtaaa aaataagaaa tacagaaaaa ttgccataat tatatctatt
    11221 cctatattgc ttgttgcgca gtactacctt tttaaatttg gaatacttag accaatggta
    11281 aagggagtag aaattgaaat tgtagatggg gaatatgtta aagatataga taaatatgta
    11341 gtaaaattaa atgaaacagt tactttgtct acaggtgaat atattaaggt tccttcgtat
    11401 gctaaaaatc caaatatttg gtttaatgta ttggataact cagggacttt aaaaatagat
    11461 ggaaataaaa tgacagcatt aaaggttggg tattcttctg tgggtatcat gaaaaattca
    11521 agagtattaa aaaaggctac tataaaagta gtagatccag aggtagaatc actagatatg
    11581 gagattaatg gggatttaaa acatgttggt gatagtgcta ctatagaaag tacaatagaa
    11641 gttgattatg ataagtttaa aaaatcatat aagccagttt ataagagtag caatgaaaat
    11701 attttaaaaa tcaaaggaaa taaagtaagt gcagttggag ttggtaaagc tacaatatat
    11761 gctaagtgtg gaaataaaga aattgagaga acatttagga ttcaagctag agttgctgaa
    11821 ataaatatgg atgatataaa aatagaagtt gaccaaaatg aaaaattgaa accagatata
    11881 ataacttctc cacctggttt agaaccacca aaaatatatt atgagttagt agattcaaaa
    11941 ttacctgtag aaagagcaat aagtttaagt agtaatggaa atgttgtagg tcttagagaa
    12001 ggtaaagata gggtgagaat aacttgtgga gataaatcta aagtaataac agtaacagta
    12061 gtcaaagaaa ctataacgaa tgactatata caaaacttgg ttggttcaca taaaatagta
    12121 aacaataaag ttattattaa acttgaatgg gattatatga aagatgtctt tgattatgat
    12181 atatatctta aagataagtt gtcaggagaa tcatttaaga aaattaaatc tataactata
    12241 aatgaaagcg atttaggtaa gtctaacaag gtatatgcga ctatagaagt agatatgaag
    12301 ggtaatcaaa atatagattt tgatatttat gtcataggga aaaaggattc agatacaact
    12361 aagccaagta atgtaataaa tattaccaat ggaaatggaa attcaaataa tgataataat
    12421 attaaagata tgagggtaga aaatatatca gctaatgttg atagagataa taatgtcatt
    12481 agagttaact ggagtagtat atctcataag gactgtactt acagtatata tgtaaaaaat
    12541 aatactaatg gagatggaga atttactcta tatcaaagtg atatacaggg aaatgagcat
    12601 actataagta ttcctgaagg agatttaaat ctagatattt atgttgttgc aaattataac
    12661 ggaaatagct ctcaaaatag tgatgttata aatgtaagat agatttgtat acaaattgaa
    12721 agtgttgagt ttatttaaat attaaattaa gaaaaaggat agtatagggt aattatacta
    12781 tccttttttg ttacaatata taggtttaaa atctctagta atataaatta taaaaagtct
    12841 tatttacaca aatctataga tatttttttt attaatcaat attgtcttaa attgaactta
    12901 gtgcggcttc tattgcatgt attactgtcg tatcaaatag tggaatagaa gtgtcatttt
    12961 gtttaattaa aagacctatt tctgtacatc ctaatataac agcctctgca ccttgtttgc
    13021 caagcttatc tataatagat aagaaagctt tttttgaaga ttcagatata attcctaagc
    13081 aaagttcgtt aaatattgtg tcatttacta ttatacggtc ttcttcattt ggaattaaga
    13141 cttcaattcc attattaata attacatttt tataaaaatc ttgttccatt gtatatttag
    13201 tacctaataa ggccactttt tttatttctt tttcccttaa taccgtagca gttacatctg
    13261 ctatgtgaag taatggaata tgtatacttt cttgtatttt atctgatacc ttatgcatag
    13321 tattagtaca gataacaata aaatctgccc ctgcctcttg taatttaatt gcagcatcag
    13381 ctaaaatttt ggcacttttt tcccaatttc cactagattg gcattcttca atttcttgaa
    13441 aatctacact gtaaagtata catttagaag agtgtagtcc acctaatctt tcttttatta
    13501 ctgtattaat aacttgataa tatgtaatgg tactttccca actcatacca ccaattaagc
    13561 ctatagtctt catattatac ctctcttatt tatttattta ttttgaaata gctatttaca
    13621 aatacaagta tagcatctaa aatagaagca tacaataata aaattgtatg gagtacaatt
    13681 ataattaaga ggagtaatta tatgccaata aattcttttg aaaactatcc tatgacatgg
    13741 aaaccaaaat tagataaccg aaaaccacca atatataaaa ctttagcaat gttattagaa
    13801 gaagatatta aaagaggaaa tttaaatcct ggagataaac tgcctccaca acgggaatta
    13861 gcagattttc tagatttaaa cttaagtaca ataacacgag catttaaact ttgcgaagaa
    13921 aagggactaa tatgtgcaaa agtgggaaag ggaacattca tttcttctga tgtaaatgta
    13981 agtaatacat tattatatca aacggaatca aaagacataa ttgaattagg gacagttcat
    14041 cctccatatg agcaaaatac atatattatt gactttatta aaaatgtact aaaacaacca
    14101 gaaatggata ggtttttaca atacatgtct ccatctggca catatatgca aaaaaagtca
    14161 attgcaaaat ggatagaaag aaataatgta tacaccagtg aagaaaatat attattatct
    14221 acaggagggc aaaatgctat atgtgcaact ttactaggat tatttaaagc tggtgataga
    14281 attgctacag attctttaag tttttctgga attaagtcaa tagctaaaat gataggtatt
    14341 caattagtcc caattcctca agaaaataat gaaatatcga ttgaatatct tgaaagttat
    14401 tgtaaaaatg aaaatataaa aggcatatat cttataccag attatcataa tccaacgaca
    14461 catactatgt ctgatttatc tcgtaaaaag atagccaaga tagcaaagca atataatata
    14521 ataattattg aagatgctat aaatagcatt tttagagatg gtatacaaac tcccatattt
    14581 tctttagcta gtgataatac tatatatatt tttagtacat ctaaattttt atgtgctggt
    14641 cttagagtag catttgtagt tgctccaaaa cgatatatag aaaatttaga aaatgcacta
    14701 tataatatga atctaatggt ttctccattt acagcagaaa tagtacaccg tttattatat
    14761 tctcctatta tagataaaat tatagaagag aaaagagatg caattataga aagaaatgaa
    14821 gttgctgata aagttttgtc agattataat ttgattggtg ataagaattg cagttttcgt
    14881 tggttacttc ttcctgatga attggatgga aaatcatttg aaatttctgc aaaaaatcta
    14941 ggagttcaag tatattgtgc tgaacgattt tcagtaggaa actctacagt tccaaaagca
    15001 gttcgtattt gtgtaacagc tccaaaagat gtagaagaat tagaaaaagg gcttaatata
    15061 ataaagtcac ttcttaagag ttaaatttat tttactatta tttaattaaa taaataaaaa
    15121 ggcggagaaa tttattataa taaacctccg cttttattat ttaatgaaat actttacttt
    15181 ttattaaaaa atttaatttt aataatcttg aaaatataat cgttttatgg taaaataatt
    15241 cttaaaaata gaaaaaatta atcatttgtt aaaaaaaatg cataatttat tgtaatttat
    15301 tgacgaaggt tgaaaaatat tcataaatgt gcgaaataac agaaaaaatg caaaaattaa
    15361 ttcaatttca tttgttataa aatctatatg gcaaaattaa atctgcctat cagaatgata
    15421 taaacacatc agaaaggagg acgctatcaa ataatacaag tagttaactt tgatagcaaa
    15481 aaattatgaa tgaacaaact agaatatcct tagagagagc tgctgaatta aaatcaaaaa
    15541 ttgatgatta tattcaggct agaaaaacga ttaacagagg tcttgaaaaa gaagaagaga
    15601 taaataaacg aaaacagaaa atattaagta tcttaaatgg aactgaagag gattggaata
    15661 actacaaatg gcaattatca aatagaataa cagatgtaga tactttatca aaaattataa
    15721 ctctaactaa aaaagaaaaa gaatatataa aagaggttgg tactcaattt agatgggcaa
    15781 tatctccata ttatttgagt cttatagacc cagaagatat atgtgaccca ataaaattac
    15841 tgtctatacc aacacatata gagttggaag atgagcaaga agatttggac ccaatgggag
    15901 aagagtatac aaacccagca ggatgtataa ctagaagata cccggataga ttaataataa
    15961 atgtaacaaa tgagtgtgct atgtattgta gacactgtca gagaagaaga aatattggac
    16021 aacaagattc tcataagtca aaagctatta tccaagaatc tatagactat atcagagaaa
    16081 atgaagaaat aagagatgta ctagtaactg gtggagatgc tcttacatta aaagatgatt
    16141 atttagagtg gattcttagc caacttaaag agataccaca tgttgattat gttagattag
    16201 gtactaggac tcttgttaca atgccacaaa gaattacaga tgaattttgc aatatgctaa
    16261 aaaaatatca ccctgtatat ataaatactc attttaatca tccaatggaa ataactaagg
    16321 aatctaaaga agcttgtgaa aagttagcaa atgcaggagt tccattagga aatcaggcag
    16381 tattattaaa tggaataaat aatgataaat ttgtaatgag atgtttaaat caagaattac
    16441 tgaaaataag agtaaaacct tattatatat tccaaagtaa acatgtaaag ggaacaaaac
    16501 atttcaatac atcagtagat gatggtcttg aaatcatgga gtatttaaga ggatatacat
    16561 caggaatggc tataccaaca tatatagtaa atgctccaaa aggaggagga aagactcctt
    16621 tgcttcctca ataccttgta tcaaaaggaa cagattacgt tatgcttaga acatgggaag
    16681 gaaaagttat aaaaatggaa gatgaacctg ctgtagatat aaagaaactt ataaaagaac
    16741 aagcacagga ttaaaaaaat atttaaagtt tataaaaaga aacaacttta aaataaaaag
    16801 aaaatggatg tcaaatttat atcaatttgc atccattttt tattagttat ttattatttt
    16861 gttgttgatt aactaattca agatatccac ttgggtggaa gtaatatatc tcagaagtat
    16921 tttcatttac aaagtaacca atatcaccat ctgcatctgg taaaaataca taaccattaa
    16981 gatttttagc ttttaatgct tcaaaatcac tagcatttcc ttgatatatg taatcaactt
    17041 cattgttgta ttttactaaa agttctttag cttgttcttg agtcaattta gtattttggc
    17101 ttacaggaac attcttttga gaatctgcat aagaagattc atttactggt gcagttaata
    17161 acaaacaaga taaaactaat aaagatataa gtgctttttt catactaaaa ccctctttca
    17221 tgtttaatta tataagattc attacttaat aatattgtat gtttcctata attaaatatt
    17281 accattaaag agaataatat tacagttaca cagctgtaac ttttgattac aaaatcgtaa
    17341 ttaaattgta tttttattcc atttgtattt tatcatgtct acgatttaca aactcacaga
    17401 agtatatctt tataacgccc atcacaggag cagatagaat cataccaggt ataccaaaga
    17461 atcctccacc aacagtaact gctaggattg taaagaatgg gctaagacct agttgtccac
    17521 ctacgatttt tggctctata aatgtaactt caacttgttg aattattatt aagtaaatta
    17581 aagaagttaa agcaattgtt ggattggaga ataaattaat tattacaact ggtgccatac
    17641 ctattactgg accaaaatat ggaaccatat tcatgacacc cataagtgta ccaaataata
    17701 gtgcatattc agattttaaa aagtaaagac caattccaga aagtactcca actataaaag
    17761 aatctaaaat cttacctgta aagtatttac caatatttaa atttaagctt tgacatagtt
    17821 ctattataaa gtctccatat tttttaccta aggaaatata aactactttt tttgtaaaca
    17881 gtaagaattt ttctttttct aataatatat agaaacaaat tataaaacct aaaagaaatt
    17941 gtactataaa ttttccaact gaaaatgtag tgctaaatat cccaccaagt gaaccaataa
    18001 gcaagttact aaatttaggc attacactca taattttgtc accatactct tttaatgtat
    18061 tagggtcaac tgattgtaaa ctcttaccta agtcgaataa gaattgctct gttttatcta
    18121 tgtatgtagg aatttgagca actaaatcag ctaaactatt tactatggat ggaactgtaa
    18181 ataatataaa ggaaattagt ataactatga gtacaccata agtaagaagt aacgaatata
    18241 ttctcttaaa atttaatttg ctttctaaga actttactag tgggttgaat atatatgcta
    18301 atacaaatgc tattataaat ggtgttagta gtgacattaa taaacttatc actccaaaaa
    18361 aatatttgta attatcaata actttaatca agatatatga aacaactaca gtgagtacaa
    18421 tatttagata aattttttta tcttgcaaaa taacacaacc tttcttatat ttattaaatt
    18481 tagatatact taaatctaag ttaaagttaa tatttatagc ttattataca ataa
//
LOCUS       DAEPXW010000079        18498 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.080, whole genome shotgun sequence.
ACCESSION   DAEPXW010000079 DAEPXW010000000
VERSION     DAEPXW010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.080"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     regulatory      68..170
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            264..1640
                     /locus_tag="KRM55_002683"
     CDS             264..1640
                     /locus_tag="KRM55_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH1594905.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(1737..2882)
                     /locus_tag="KRM55_002684"
     CDS             complement(1737..2882)
                     /locus_tag="KRM55_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1594906.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            3135..3842
                     /locus_tag="KRM55_002685"
     CDS             3135..3842
                     /locus_tag="KRM55_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594907.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            3889..5484
                     /locus_tag="KRM55_002686"
     CDS             3889..5484
                     /locus_tag="KRM55_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1594908.1"
                     /translation="MSNLSILIKNNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKVLMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNVYIILASIL
                     TLILDFMIWRIISTKGVKIFKNL"
     gene            5587..6669
                     /locus_tag="KRM55_002687"
     CDS             5587..6669
                     /locus_tag="KRM55_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH1594909.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            6818..6979
                     /locus_tag="KRM55_002688"
     CDS             6818..6979
                     /locus_tag="KRM55_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBH1594910.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            7320..8588
                     /locus_tag="KRM55_002689"
     CDS             7320..8588
                     /locus_tag="KRM55_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH1594911.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            8783..9571
                     /locus_tag="KRM55_002690"
     CDS             8783..9571
                     /locus_tag="KRM55_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH1594912.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDCEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            9571..10020
                     /locus_tag="KRM55_002691"
     CDS             9571..10020
                     /locus_tag="KRM55_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH1594913.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            10024..12288
                     /locus_tag="KRM55_002692"
     CDS             10024..12288
                     /locus_tag="KRM55_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1594914.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQGLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            12428..12739
                     /locus_tag="KRM55_002693"
     CDS             12428..12739
                     /locus_tag="KRM55_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594915.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            13025..13525
                     /locus_tag="KRM55_002694"
     CDS             13025..13525
                     /locus_tag="KRM55_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBH1594916.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYILGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            13582..14568
                     /locus_tag="KRM55_002695"
     CDS             13582..14568
                     /locus_tag="KRM55_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH1594917.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            14618..15340
                     /locus_tag="KRM55_002696"
     CDS             14618..15340
                     /locus_tag="KRM55_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBH1594918.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNENIRVGLLYN"
     gene            15369..17303
                     /locus_tag="KRM55_002697"
     CDS             15369..17303
                     /locus_tag="KRM55_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1594919.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFNKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            17296..>18498
                     /locus_tag="KRM55_002698"
     CDS             17296..>18498
                     /locus_tag="KRM55_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBH1594920.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKHLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIHIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTV"
BASE COUNT         7067 a         1835 c         3160 g         6436 t
ORIGIN      
        1 aatacaatat atacgtatat attgacaaaa ttaattatat aaattaaaat aatattcgta
       61 aagaaaaatt catgttttgt actgtataac atataatttt gacaatatgg gtcataagtt
      121 tctaccggaa taccgtaaat attctgacta tgtatactat tatttagtta attaaatatt
      181 taattaactg aattatgaag gatacggctc agcttatcaa ctactgtgtc gtttttttgt
      241 aaaatttaat aggaggtgtt gttatgcaaa caacaaacag tagtactatg cagaaacttt
      301 ttccaatttt gactaataaa aatgtcgaca tgaagaagga aataattgca ggagtaacta
      361 cttttttaac tatggcttat ataatagctg taaatccaaa tattttatct gagacaggca
      421 tgcctgcagg tgcacttgtt acaggtactt gtttagcagc agcatttgga tgtattttaa
      481 tgggtgtagt tgctaacctt ccttttgctt tagcatcagg tatgggtctt aatgcatttt
      541 ttgcatatac agtagtttta caaatgggtg ttccttggga agtagctctt acagcagtat
      601 ttgtagaagg tattattttt atagtattat cagtaagtgg agttcgtgag gctgttgtaa
      661 atgcgatacc aaaaaatatg aaattagctg ttacaggtgg tataggaata tttattgcac
      721 ttataggtct agttaacagt ggaattgtta ttggagacca agccactctt atcaaaatgg
      781 gtagatttac accagcagta ataataactt gtgtaggatt aataattatt gctgtattag
      841 ataaaaaaag agttaaaggt tctatacttt ttggaatagt agtgagttca ttacttgctt
      901 gggcatttgc ttttataaat ccagagtatg cacaaaaatt aggtatatat ttacctggtg
      961 gattatttaa attcgaaagt ttagcaccaa tagcaggtaa aatagattta ggatatgtac
     1021 tacatccaac aaatataggt ggttttttag tagtagtttg tacattttta tttgttgatt
     1081 tttttgatac agtaggtaca ttagttggtg tttgttctaa agcaaacatg ttagatgaaa
     1141 aagggaatgt tcctaatgta ggtagagcct tacttacaga tgcggttgca actacagttg
     1201 gtgcaggact tggagtatct acagttacaa cttatgttga gagttcaaca ggagttatcg
     1261 caggtggaag aactggatgg acagcaataa cagttggaat tttattctta gctgcaatgt
     1321 ttttctctcc tgtatttata gcaattccat catgtgctac agcaccagct ttaatatatg
     1381 ttggatattt aatgcttggt acagttaagg atatagagtt tgataatata actgaaggtg
     1441 ttccagcttt tgttactatt gcttgtatgg cattaacata tagtataggt gatggtttaa
     1501 ctttaggtat attaacttat gttttcgtaa atatatttta taatatattt ggagctaaaa
     1561 aggcagaaga caaaaaacat gtttctgtag taatgattgt tctggcaata ttatttataa
     1621 taaaactttg gctactataa taggtattat ttaaaatttt aatttaatat aaaataaagg
     1681 gctgtaattt attatcaatt gtgatgataa actacagctc ttttgtattt gttgtattat
     1741 ttaataatgt ctattagttc tccattttgt aaagttttag gtgtaattac tatattgaac
     1801 tctttttgca aatcttttat aatatctaat tctttttttg ttattattga gattgtgtta
     1861 ccacttcgat ttcctctagc agttcgacca catctatgca ggtattcatt tttacttttt
     1921 ggaaaatcca agttaaaaac atgacttaca tccacaatat ctagtccacg agcagataaa
     1981 tcagttgtaa ttaaaatctt tgctttacca agtttaaatt tatttattgc attctttcta
     2041 tcttcttttt ccatatttcc aaaaattcct attgctttgt aattatgata atttagtttt
     2101 gatactagga cttctatatt tttttcatta tttacaaata caatagcttt ttttggattt
     2161 gtagctgcta atgcctttct aagaaaagta aatttatccc ttatctcacc taataaatat
     2221 gagtgattga tgttaggatt tatttgtgat ttttcctttg tttttattat ttcaaactcc
     2281 ttcataagtt tatcacaaat ttttatagtg ctatcagtaa gacttgcaga gcatcctata
     2341 atttgtctat ctcttaacgt tgttcttatt atgtcttcta tacaagttat attttttcca
     2401 ttcaatagat tgtccacttc atctaagaca atagttttta tattatgtga ttttagtttc
     2461 ttttgtttta tcaagtctaa aactcttcca caagagccaa ttactatgtg tggttttact
     2521 gcttttatat tttttatttg tttttgtata ttgacctccc caattaaagc taaagaagta
     2581 acggagagtt ctgcattttt agccaataat tcaacctggt ttgtaatctg cattactaat
     2641 tcatgcgtag gtgcaagtat aagagcttgt gtttctcttt ttgatgtatc aattttttca
     2701 aatataggta aaaggtacgc tagtgttttt cctgttccag tctgtgaatt aatcaataaa
     2761 tccttatttt gaattatatt ccctataaca agtgactgaa cttctgttgg agaagttatg
     2821 tcttgttttt tgagtccatc tattagagtg gaacttattt ttaattgttc aaatgtattc
     2881 atattttact ccttatattt taataattat agtcaactat tttttattat acattgttta
     2941 ttcaaatcga actatatatt cttttataat tatgtgtaat ttgaaagtaa atatcaatta
     3001 tatttatacc tttatatttc tgataccttt gcattttata gatttctaaa ataaacaaat
     3061 aaaagttgta attgtttgat atttgttata tattatatat aacaaatatc aaaactataa
     3121 tatggaggga aattatgtta aaagtaatca atgtatctaa atcatataaa aataaaaaag
     3181 tagtaagtag tgtctcattt gatgtaaatg atggagagct ttttgggttt ataggacata
     3241 atggagcagg taaaactact actattaaag caattgttgg aatacacgat tttgaagagg
     3301 gagaagtact aataaattct aaatctataa aaaaacagcc tgttgaatgt aaaaaggaaa
     3361 tggcatatat acctgataat ccagatttat acgagtcatt aactggtata caatacctta
     3421 attttatagc tgacatattt gaagttgcca aagataaaag agaagagtta ataaaatatt
     3481 attcaaataa gtttgaactc aataaagcat taggagattt aatatcttca tattcgcatg
     3541 gtatgaaaca aaaattagct ataatttcgg ctttgataca cagcccaaaa atcttaattc
     3601 ttgatgaacc ttttgtaggt cttgacccaa aagcttcctt tatattgaag gaaattatga
     3661 gggagttttg tgacaaaggt ggttgtatat ttttctcaac acacgtttta gaagttgctg
     3721 aaaaaatttg tgataagatt gccataataa aagatggaaa tataattgct tatggaacta
     3781 cagaagaagt taagggaagt aattcacttg aaagtatctt tatggaatta atagagaaat
     3841 aaaatgtttt ttatacaata tagtgtctaa agtgaggaat gataaaatat gagcaatcta
     3901 agtatattaa taaaaaataa tataataaat gaatttaaat taaatgcgtt aaaaaaagct
     3961 gatggtagag aaaaacaaaa aataatggga atgatgcttt cagttgttat aatagcgggt
     4021 ctattaattt tttatgtaac gagcttaagt ctctctttag ttgatatctt aaagcaaata
     4081 aatcaactgg aaatgctact gatatttggt tttggattat caacattaac aactattgtt
     4141 acatcattat ataaaacatc atcatatcta tttcaagcaa aagatttaga ccttttgact
     4201 agtttaccta taaaagaatc tactgtacta gcaagtaaga tattaatgtt ggttggagca
     4261 aactatttat tttcttcaat atgtatgatt atacctgcag tggtttactt tttaaattct
     4321 gatgtaagta taacttattt cccttatttg atattgctat ttttagcttt accattatta
     4381 ccgatagttg cttcatcaat aatttttcta tttatagggc agatatcatc aagaataaaa
     4441 tacaaaaatt tagtattaat cataggtagc attatattga tgttgcttta taccctactt
     4501 atgtcaagac ttaattctat gtcagttgaa atgctaaaga atagtgtgtc tatttcagag
     4561 acaattagaa aagtatatcc tcctatatat tattttgttg atgctcttaa aacaggaagt
     4621 atagtttcat ttttagcatt tatagccatc tcgataatac cattttttat gtttgtaact
     4681 ctgtttgcaa aaaaatttaa agatataaat gctaagatga gtgaaggata taagtcaaaa
     4741 aattatgaat ttaagggtca aaaaacttca agaccttcaa aagctttatt aaaaaaagaa
     4801 tttaagagat atacttcttc gtttatatac tttttaaatt catctgcagg tttgttattt
     4861 ctaatagtag gtacaatttt aatattatta tttggagcag ataaagtggg tgagttactg
     4921 aaattgaata tagattttaa tcttataaaa atacaattat tgggagtatt cttctttata
     4981 atagtaatga attgtacaac atactgttca atttctcttg aaggaaaaaa tttatggata
     5041 ctgaaatctt ctccaataga tgaaagagaa atattctggt caaaagtatt aatgaatttt
     5101 ttattgaatg ccccattatc tattttatgt ctaatattag tatctataag attagacttt
     5161 gaaattcagt ttattattgt atcaatctgt ttgattgtaa gtttttcaat gtttgtagca
     5221 ttgatgggat tattatcaaa tttattatac ccaaaccttg attggaaaaa tgaggtggct
     5281 gtagtaaaaa gaagtgcaag tatgatagtt acaatgttag tatcattagc ttatgtaatt
     5341 atacttggag gtatatatgt attacttgga atttcgtttt taaatgtata tattattttg
     5401 gcaagtatac ttactttgat attagatttt atgatatgga gaattatttc tactaaagga
     5461 gtaaaaatat ttaaaaattt ataggtgtat ttatgtcaaa taaagactta tcttttttag
     5521 tcttgcaaat aataggttaa gtagtatact atgtatagtg atatgaaaaa atttaggaga
     5581 aaataaatga gaaaattatc caaaagagaa aaagatttta ttcaatatgg atttttatta
     5641 tttttgatat gtattactac ttatttagta ttaactactt tagatataaa actaatacct
     5701 aaaattataa ggctagtaaa taagacttat atatttcttg gcatattgac aattatagta
     5761 tatatgataa ttgaatctat tgtaactcat ttgataataa atgcagttca aaaaacaaaa
     5821 gtgaaattta ttggtattaa aatggctaca atgggatttt actataactt agttactcca
     5881 tttgcatctg ggagtcaacc aatgcaaata tatgcactta caaaatatga tgtaagcctt
     5941 agtaaatcag tggctatagt tactaataaa actgtagtat ttcaaagtac agttaccgta
     6001 ttttgtggaa ttttaatttt gctaaataag tcattactga tggagcaagt acattctgtg
     6061 aaagtcttga taacttttgg aatgattatg aatgtaagta tgttgttagg tggactacta
     6121 atagtattta gtccaaaaca agtaaaaatg atagcagaag ttttgattaa ttttttatct
     6181 aaatttaaaa catttaaatt tttagattca aaacgtgata gaataaatca ttatattgat
     6241 gattataatt attctataaa aatatttatt aaaaatgtaa gaatcttagt tttaagtata
     6301 ttacttactg tgttacaatt aatcgcatat ttcagtatag tttattgtgt gtataaagcc
     6361 tcaaatttaa gaggagtttc atatgtacat ataatgacat tacaggtctt tttatatatg
     6421 gctatatcac caattccaac accaggaaat gttggagcta atgaggttac attttttact
     6481 atgttctcca atataattcc aaaagaatta ttggggtact ctgtactctt atatagtggg
     6541 tttgtatact attttatatt aatagtttca ggtttattta catttggaac gcattataca
     6601 ttaaattctt ggaaaaagga agataaagta aattctaatt tagataaggt tattgaaaaa
     6661 ttaaattaat aaaataatta gggaaattct atatataaat atggtgttga ataagctata
     6721 ttatattgag atatttccct tttttgatta aaattataga aatttgaaat aataagtaat
     6781 aaacagaaaa agtgatattg ttttgaaagg agaaactatg aaacaagata aacaaaatga
     6841 aaaacaaagt gagatttcta agataaaaca aagcaatgat aataaacttg aaatagctca
     6901 agaattacat gtaagtaaaa atatagggaa tatgcttgga tatagaatag ataagaaaaa
     6961 aatgaataga ccaagttaat gaaaatgttg aaaatggtac attttaaaaa atatatataa
     7021 tgaaatgttt tattgttaaa tttaaactta ttttaatgga ggaaaaagtc gaaaaatatc
     7081 taaaaagata tggatataaa aaatattaat atatatatac tataaacttg acaaaatcaa
     7141 ccttttaata actagcaaaa aatagcaaaa ttatataagc gttatttaat tgtcaaaaat
     7201 gaaagctaaa ttgcatgtcc taaaaaaaat gattgataac atttatttgt gtgctataat
     7261 tatatagtaa aacaataagt atattgcata atgtatgcaa atcgggagga gagacagaca
     7321 tggaagcatc tatacacaca attgccagca ataatttatt gataattttt gctattgtaa
     7381 gtataactgg aataatttgt agtaagctta gtgaaataat aaaggttcca gatgtagtgt
     7441 tatatttact tgtaggtatt ttaataggac catcattttt aaaatttata gatattcgtg
     7501 gatttcaaat agaaaatcaa ctaatactta catttggttc tgcatttatt ttatatttag
     7561 gtggaaaaga aataagttta aaagtattga gaaatgtgaa gatatctgta ttcttattag
     7621 ctactttagg agttgtgata tctgctttta taatgcaaca agtaatagga tttacttttg
     7681 ggataagtgc aatgactgct ttactagcag gaactataat agcatcaaca gacccagcca
     7741 ctcttgtacc tatatttaat caggtaaaga taaaggatag ggtaaaacaa actgtaataa
     7801 gtgaatcagc ttttaatgat gcaacaggag ctatactaac atcagcagtg ttggctgtaa
     7861 ttttgtcaaa taaattttca ttaggtgaaa atatttatga actggggaca atggttattg
     7921 tcggagtttt agttggttta attacaggaa tactgctttt gaaattagtt aatgataaac
     7981 cttatggaat atttaaagat tttgcaccaa taatatctgt tatttcagtt gtagttgcat
     8041 atgaattatc tacaaaatta ggtggaagtg gatatatgtc ttgctttatt gtaggtataa
     8101 taactggtaa caagaaaaac tttaaaattt ggttaagtca aaaatcttat gatgcagatt
     8161 tttatgttgc tgaaacttta ggtactattt gtcgtatggc aatatttata atattgggta
     8221 gccaagttaa tttggctcag ttaagtaaat attttatgcc atctgtaatt acagtattag
     8281 tattaatgtt tatagcaaga ccactttgcg ttttagtttg tacacttgta gacagggaag
     8341 caaaatggag taaaagtgaa atattattta tgatgtgggt aagggaaaca ggcgtaatac
     8401 cagcagcact ttgtggtatt atttcagcaa tgaaagttcc tggatacgaa gtgatttcat
     8461 ctgtagtatt catgactata ctaattacat tagtaataca aggaagtact acaaaattag
     8521 tagctaaaaa acttggatta ttagaagaag aagtgataaa tataagtgaa aaagtatcga
     8581 ctttttaaag ttttgcttta aaatagtacc tgttaatggc tattttaata ttgtctaatg
     8641 atgattattg aaatagtcat ttttttatgt ataagtaatt tacagaattt acatattaga
     8701 catatttatt atcaaaattt gttgaagcta tgatataatt agttgtattt aaaataagaa
     8761 tagcaaataa gggaggaaat ttatgtttac ggttatggat attgtacagc cagatacagt
     8821 agaagaagcg tactcaattt taaataaaag aaaaactaac caagtaattg gtggaagtgc
     8881 ttttttaaga atggggaaaa aaagaatagg aacaggaata gaattatcta aattaaattt
     8941 agattatata aaagagtatg aagattatgt tgagattggt tctatgacta cttttagaac
     9001 attagaaaca agttccataa taaaaaataa ttttggaaga ataatagaag attcagttaa
     9061 aaatataata ggagttcagt ttagaaatgt agtaacagtt ggtgcaacag tattttctaa
     9121 atatggtttt tctgacttga tagtagcatt actttcatta gatacggaag tagaattata
     9181 taatattggg agaattagtc ttgaagagtt tctaaataga gattgtgaga aagatttact
     9241 tattaagata tacataaaga agacaaataa gaatgcttct tataaatcac ttagaaatgc
     9301 aaagagtgat tatccaattc taaatgtatc tgtatcaaaa catatggaac aatttaagtt
     9361 atgtgtagga gcaagaccgc agaaagctac gattgcaaaa caagctagtg aatttctatc
     9421 taacaatgaa atcaatgaaa ttaatataga taaagcagta gaaatagcat cagaagaact
     9481 aacttttggt tctaacatga gagcatctag ggagtataga aaagctatga gtaaagtact
     9541 tttaaaaaga gctataatgg aggttattta atgttagtaa agattaatat aaatgggaag
     9601 aaaaaaagtg ttgatataga accagaagaa tatctggttg atactttaag aaaagttggt
     9661 aatttaagtg tgaaaagagg ttgtgacaca ggttgttgtg gtttatgtac agttttaatt
     9721 gacaagaaac ctacattatc ctgtgcaaca ctgacattga gagctttaga taaagaaata
     9781 actacaattg aaggtttaga aaatgaagtt aaagaattta gtgaagtttt ggtaaaagaa
     9841 ggagctgagc aatgtggttt ctgttctcct ggctttatac ttactgtact tgcaatgaag
     9901 gatgagcttg aaaatcctac agatgatgaa ataaagcatt atcttacagg aaatctatgt
     9961 agatgtacag ggtatatggg acagttaaga gctatcaaaa cttatctgga ggtaaaatag
    10021 aacatgaata tagttggaaa aggaatcaag aaaatagatg gaatgagtat cacaacagga
    10081 aagcctgtat atacagatga tttatcagca aaagatgctt tggtggtaaa gatacttaga
    10141 agtcctcacg cttatgcaaa aataaaagat atagatacat caaaggcaga aatggttgat
    10201 ggtgttgaat gtgttttaac atataaagat gtaccaaaat ctcgatttac acttgctggt
    10261 caaacatatc cagagccatc tccatatgat agattaattc ttgaagatgt tgtaagatat
    10321 gtaggtgacg aagtagctat agtggcagct atagatgaaa aaactgcaat taaagcaatg
    10381 aatcttatca aagtaaagta tgaagtactt acacctgttt tggattttga agaggcaata
    10441 ggaaataaaa ctatggtaca tgatgaagat agacattgta actttgatat aggtatgcaa
    10501 agagaaaaaa atatagtatc ccatcatgat tatacaaaag gtgatgtaga aaaagtatta
    10561 agtaattgtg atgtagtgat tgaagaaact tattatactc aagctcaagc acatgcaatg
    10621 atggagacgt atagggcata caattattta gaccatatgg gaagattggt tgtagtaagt
    10681 tcaactcaaa taccatttca tgtaaaaaga catttatctc gtgcactaga aataccagct
    10741 agcaaaatta gggttataaa acctagaatt ggtggcggat ttggtggtaa acaaactgca
    10801 tgtgttgaga ttttttctgc aattgttact ttaaaaacag ggaaaccagc taaaataatt
    10861 tatgatagaa aagaaacttt taattgttca acaagtagac atgcaatgag attaaaagtt
    10921 agactaggtg ctacaaatga tggcataata aaggcaatag atataaaagc actttctgat
    10981 acaggagcat atggagagca tgcttctaca actattggtt tggttggaga aaaaacttta
    11041 ccaatgtata ataaagttga agcaacaaga tttattgcag atgtggtata tactaataag
    11101 atgccagcag gagcacttag agggtatgga gcatcacaag gatgttttgc tgttgaatca
    11161 actataaata tgcttgctaa taaattaaaa atggacccaa cagatttaag gttaaaaaat
    11221 gtggtaacag aaggtgaaac tacatttgca tatggtaaaa ctttaaatag tgtcgattta
    11281 ataaaatgta taaataaagg caaagaactt attggatgga atgaaaaata tccttgtaaa
    11341 catcttgata atggaaaaat tagaagtgtg ggtatggcaa ttactatgca aggttctggt
    11401 atacaaggtc ttgataagtc ttcagctgaa ataaaattga atgactgtgg agattatact
    11461 cttatgatag gttctactga tatgggtaca ggaagtgata cgattttagc tcaaatggct
    11521 gctgaggttc ttgatacaag cattgaaaat ataacagtta tatcagctga tactgactta
    11581 gttccatatg acccaggttc atatgcttca agtactactt atgtaacagg tatggcagta
    11641 gttaaggcag ctcaaggctt aagagaaaaa ataatttctg ctggagcaac taaactaggt
    11701 gttgagaagg atgaagtaga atttgatggt ataaaattaa ctagtaaaaa aggtagcact
    11761 ttattattcg atatagcagt tgattctaca attggcccag atactaatca attaataggt
    11821 cttgcttctc atggtagccc agtatctcct ccacctttta tagcaggttt tgcagaaact
    11881 gaaattgaca cagaaactgg aaaagttgat ttagtaaatt atgtagctgt agtagattgt
    11941 ggaacggtta taaataaaaa tctagctaag atacaagttg aaggtggaat tgttcaaggg
    12001 attggaatgg cattatttga agaagttaga tacacagaaa aaggaagcat ggacacaaat
    12061 acatttatgc aatacaagat tccagctaga tgtgatattg gaaatgttaa agtagatttt
    12121 gttgaaactt atgaaccaac tggaccattt ggtgctaaat ctgttggaga agttgttata
    12181 aatacacctt taccagcaat acaagaagct gtgtttaatg gaattggtgt aagaataaat
    12241 acactcccta ttacacctga aaaagttttt atggaaatga ataaataatt atttatgaaa
    12301 atttagacta gttttacatg ttaaacaacc agttatgtca tacctgttga aagatattta
    12361 ataagtagtt attataatat tatgaatttt acttataaaa tacaaaatta aataagggga
    12421 tgatgttttg gctggtaatc taaataatat gagagcagta aataatttta gaggagataa
    12481 gaacatttta gaatgtttag tcagctttga gggtcgttca ataagtcaga gaaaagtaag
    12541 ggtatttttt aaagaaaaac aaaatcaaat agaaattgat tttgcagaag aggaaatttc
    12601 taaattggtt gaaaatgttg ttttaaatac atcatatcaa gaaatgttat atgatgaaat
    12661 agagaaacaa ctggaaattg attgtatagg tacttggatg atattatcta aattaaaaga
    12721 tggtagtaga gttcactgat tttaaaataa attattagag cctaatttta aggctctttt
    12781 ttgctgtttt taattaacaa tagaaaattt atctttagtt tgtatataat tttaatatca
    12841 tatattctat atatataaaa ttgaatttgt atgtattata ttgtataata taaaatgaat
    12901 tgggaaaata gttcgctaaa ataatttgtt tttataaaat tactgtttaa gtttatagat
    12961 tttgtataaa ataaagttat gttattaatt tttttaaaaa taaaactttt actaggagac
    13021 agatatgaga aaaaatagta ttaatatagc actaactgca gcaattacag caatctatgc
    13081 agttttaaca ttatcattgg gatttataag ttatggacca atacaattta gggtagcaga
    13141 gattatgatg cttttggcat ttttagataa aggatatata ttaggtctta cattaggttg
    13201 ttttttagca aatgtaatag gaccatatgg tgtacctgat ataatttttg gaacattagc
    13261 cacatttata agtgcaagta tgatttatat tactagaaag ttaggtaaac agaataaaag
    13321 tactttagtt atagcttctt tatggccaac tgttataaat tcgattgtgg ttggtctaat
    13381 gttaaatgta ttctttgggc ttccattaat tctatctatg atacaggtag gttttggaga
    13441 atttgtagta gtaacaattg taggagtacc atttttctgc tttttaatga aaaaatataa
    13501 aaatgtcatt aatattaaat tttaaatagt gtatagtaat ttaattaatt gagagtatta
    13561 ttagtgaaaa gaggtgttta tttgtcgaag gtaaaaagat tgactgatgt ttggatatat
    13621 attaatgata agcaaaagtt tacaataaaa gagttgtcag aggaatttaa tctttcagcc
    13681 aaaacaatac aacgatattt aaaagaatta aataaaatgg gacttccaat tcaagcagaa
    13741 caaggtagaa atggaggtta tagggtgcta aataatagct atatacctcc tgttatattt
    13801 acagaaaaag aagttatgat tatactattt gcacttaagt cacttcagat ttataattat
    13861 aagttaatgg aaatagaaat taattctata atgagaaaag taagttatga acgtaaaagc
    13921 agtataaaag taggtataga aaatattaaa agatacattg gctttgtagc taatgatact
    13981 aatgatggag attttaagag tagtaatgta actgagtttt ttagagcttc ttcagaatct
    14041 ctaattttaa atattaagta taagtgtggt aatcagattt tggaaaaaaa cgtatgccct
    14101 ataggtatat atttaaataa gggagcatgg ttttcaccag catatgattg taaaagtgat
    14161 aaaataatat tagttcatat agataatata attgatataa aaagaacagg agaaagtaaa
    14221 aaaatacata taaacttgga agaatggtta catgaagtat ataacaattt atatggaaat
    14281 agttcaacta ctaaaaaatt tggtgaaatt atttatctaa atgtattatt aactaaagaa
    14341 ggtgtttcta aaataaagga cagttcttgg aatttagata tggagctaaa tgaagatggt
    14401 agtggaataa ttagtacatt cataaaggtt gaagatatag attgttatgc ttcgatttta
    14461 ttttttattg gaaataatgc taaggttata gagccaaaat ttttgaataa gctactttat
    14521 gataaggcca atgagttaag atatttttat gaagaaaata tggtataata tttagaaatg
    14581 ttgaaattaa ataattatta aggagatata cgttataatg gaaaatttta ataagaatgc
    14641 taaaataatt ggtattggag ctgaaggtat taatataata aatgaagtag aagaaaaaat
    14701 aaaagcaaat atggatatag aaaaaataaa cataaatcaa gagattgaaa aagaatatgt
    14761 tagaagtctt ttagatggtg tagatatatt atttttgata tattcatctg aagataaaca
    14821 tattagagat attataaaag ctgtttcata tatgtcaaac gaaagaagag ttctatctat
    14881 aggaatggat tgttcagaga aagaaaataa agaagattta gagcttggga gagagtttaa
    14941 aatcaataat gatagtatat ttaaatttgt tgatttaatg aatatcatgg tagagtctat
    15001 ttctgattct tgcatgataa atatagatat tactgattta aaagaagcta ttgtaggaga
    15061 taaaggaatt aagtattctt ttgaagagtt tgaagataca aagtcatata gcgagatagc
    15121 tgacatttta tttgacagga tggaatatat tggtgaggaa tttataagta agaaaggaat
    15181 tgtatttgtt gaaggaagtc cagaattttc tataatggaa ttgaatgatt taataagtaa
    15241 tattcagagc aaggtagaag aaagctatga agtaatattt tctttatata taaaggaaaa
    15301 tttaaatgaa aatattagag taggcttatt gtataattag tatattttag atattaagga
    15361 gagtgtatat gtctgaaaat ataagaggta cagagtattg gttaatggaa gaattttttt
    15421 atcaggaaac agacacacca cagattttta gagaagaaag cataattgca cttggatttg
    15481 atataaaaat aaatttaaaa aaagtattta gtatggggaa aaaatcagaa aagtatatta
    15541 atgagaattg taatgataaa gattttataa aaaagtttat gtcgattaaa aaaggagatt
    15601 attttttata taaagcatat caaaatatag aagaaaaagt taaatgtaat gtgtctattg
    15661 gcatagttga agaagatttt gaaaatggat atgaattaag tcatatttta gggcatacac
    15721 taccagtaaa atggatgcat aattttgata cagtttcaaa ttgtaaagta tatacaagtg
    15781 aattttataa attaaataat aatgatatta gctcatattt agaaattatt aagtcacaag
    15841 ataagaaatt attgagaaaa agaatagaag aaagtgaaaa taataaatgg tatttaaaaa
    15901 actattatta taaaaatgta gataagtgtg tagatgatga agaattattt attcagccca
    15961 ttaatctaga acaattagaa agcctaaaaa atataaagac agatgattat attttattgt
    16021 ataatagcga gaaagtaatt tgtgaaaatg accatacaat gaagagtcta tttggcgtat
    16081 gtcaagttat ggaagggttc aataaagaga aagtaagtgc tttggagggt ggatattttt
    16141 ttcctgttag atggatagag tatgaaaagg agaatataga cggaaatgca tgggttatat
    16201 ttgaaaataa tagtatagtt gaaaagtatg taaaaagatt tactaataaa atgccattaa
    16261 atactatact ttatggacca ccaggaactg gtaaaacata caatacaaaa cagatggttt
    16321 acaatctagt aagtgaaacc agtctaagaa acagatacta tacaggttac ttagattata
    16381 aaaacaatgt agaattttgt acatttcatc aatcatatgg atatgaggaa tttatagagg
    16441 gtcttaagtc tgatggtgaa ggcaatttta agccagaaga tgggatatta aaggatatat
    16501 ctatagaagc atgttataat gcattgaaat ttgaaaaaaa gatgagcttt gagttggaaa
    16561 aagatagctt gactttagaa actataaaag acaggaaaaa gaaattagta ttagaaaata
    16621 tagaatatag tgagagtttt aattttgaag aatcagaaaa ctatgtttta ataatagatg
    16681 aaattaatag agggaatgta tctaaaatat ttggtgagct aataacatta ttggaagatg
    16741 ataaaagact tactaaatca aatcaaacta ttgtcaaact accatattca aaggaaaaat
    16801 tttctctacc tccaaatttg tatatagttg gaactatgaa cacatcagat aaatcaatag
    16861 cacttttaga tatagcttta agaagaaggt ttaattttga agaaattatg ccagattatg
    16921 atttattgtc tattgtagat ggtatagata ttagaaaaat gctatataca atcaataaaa
    16981 ggatagagtt tttatatgat agagaccatg ttattggaca agcttatcta cttgctgtag
    17041 aaaatattaa tgatatagta gtagtattta gaagtaaaat aataccactt cttcaagagt
    17101 atttttatta tgactcagaa aaagtaggtt tgattttagg aggaattgga agaaatgaaa
    17161 aagataaata cattgtttat aaagaaaaac ttatagcttc tgagttattt aaaaataata
    17221 atgcttcaat aatggagagt aaagttaact attgtataaa acaaaacata tctagtgagg
    17281 agctaaaaaa tatatatgag taaaaatata tatgttaagg aaacctatga atggataagg
    17341 gtaggtaatg gtgaaaatga gcttacagaa attgaatatg aaaaattgct taagcatcta
    17401 gagaacaata atgatgtatt aaaaagtaat ataatagata ttaaatacaa aaaacttaga
    17461 tttataaact atgtaggcat catatgtttt gaaaatgtaa tacttgaaat acttcctaaa
    17521 ttgtcattaa gtgataatct tgtaaaagat agagagatac tattacagat gctttctata
    17581 tgtaataaaa ttccaattac aatgaatgaa aaaataagat tgagtttgaa aaattataat
    17641 ctcttaaatt tttttgttat gtatttcatt gagagtatgc aaacacagat gaaaaaaggt
    17701 atttattttg aatatataaa taaaatagag aacttaaatg ttatgagggg taaaatatta
    17761 ttaagtacat atgcaaaaga aaaaggcatt tctccaatga aaataagatg tgaatatgat
    17821 gagtatagtg aaaataattt cttgaatcaa gttcttaaaa aagcatgtat atctatttta
    17881 tgtagaataa atgacaattc aattcaaggc aagattaaaa aaattttaag ctattttcaa
    17941 aatgtagatt taattcatat agatagaaaa aaactgttgg attataaatt ttataaaaac
    18001 aatgatagat ttaaagattg ttatttacta gctagacttc tacttttaaa tttgtctatg
    18061 gataatagtc aaaataatca agaggcattt tctatattat ttgaaataaa tactttgtat
    18121 gaagaatata taggaatttt aatcaaaagt atatgggaca attcatttag agaaacatat
    18181 atacaagata agagtaaatt tcttttgaaa aatgaacaaa caggtaagaa aaactttaat
    18241 ttaagaccgg atatagtttt atatgactta aaaaatgaat atgaaattat aattgacact
    18301 aaatggaaag ctattgaagt agattcaaat gttttttata ggtcaagtga tatataccag
    18361 atgtatgcat atataacagc atatgaaaat gcaaaaagat gtatattatt atatccttgt
    18421 attcaaaaag ataagaatta tagttcctgg aaattatcag aatcatttaa gggtaagttt
    18481 atagaagcaa aaactgtg
//
LOCUS       DAEPXW010000080        17858 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.081, whole genome shotgun sequence.
ACCESSION   DAEPXW010000080 DAEPXW010000000
VERSION     DAEPXW010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17858
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.081"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(67..1743)
                     /gene="bclA2"
                     /locus_tag="KRM55_002699"
     CDS             complement(67..1743)
                     /gene="bclA2"
                     /locus_tag="KRM55_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBH1594921.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGPTGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGENGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(2121..2660)
                     /gene="hpt"
                     /locus_tag="KRM55_002700"
     CDS             complement(2121..2660)
                     /gene="hpt"
                     /locus_tag="KRM55_002700"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH1594922.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRHINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(2988..4295)
                     /locus_tag="KRM55_002701"
     CDS             complement(2988..4295)
                     /locus_tag="KRM55_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBH1594923.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDVAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(4720..6495)
                     /locus_tag="KRM55_002702"
     CDS             complement(4720..6495)
                     /locus_tag="KRM55_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1594924.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(6707..7276)
                     /locus_tag="KRM55_002703"
     CDS             complement(6707..7276)
                     /locus_tag="KRM55_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1594925.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(7460..8095)
                     /locus_tag="KRM55_002704"
     CDS             complement(7460..8095)
                     /locus_tag="KRM55_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1594926.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(8763..9644)
                     /locus_tag="KRM55_002705"
     CDS             complement(8763..9644)
                     /locus_tag="KRM55_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH1594927.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(9764..10771)
                     /locus_tag="KRM55_002706"
     CDS             complement(9764..10771)
                     /locus_tag="KRM55_002706"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBH1594928.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(10791..11273)
                     /locus_tag="KRM55_002707"
     CDS             complement(10791..11273)
                     /locus_tag="KRM55_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH1594929.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            complement(11291..11758)
                     /locus_tag="KRM55_002708"
     CDS             complement(11291..11758)
                     /locus_tag="KRM55_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH1594930.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(11773..12531)
                     /gene="prdD"
                     /locus_tag="KRM55_002709"
     CDS             complement(11773..12531)
                     /gene="prdD"
                     /locus_tag="KRM55_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBH1594931.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(12611..13336)
                     /gene="prdB"
                     /locus_tag="KRM55_002710"
     CDS             complement(12611..13336)
                     /gene="prdB"
                     /locus_tag="KRM55_002710"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(12884..12886),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBH1594932.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(13374..13658)
                     /locus_tag="KRM55_002711"
     CDS             complement(13374..13658)
                     /locus_tag="KRM55_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594933.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(13739..15619)
                     /gene="prdA"
                     /locus_tag="KRM55_002712"
     CDS             complement(13739..15619)
                     /gene="prdA"
                     /locus_tag="KRM55_002712"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBH1594934.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(16048..17808)
                     /gene="prdR"
                     /locus_tag="KRM55_002713"
     CDS             complement(16048..17808)
                     /gene="prdR"
                     /locus_tag="KRM55_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HBH1594935.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
BASE COUNT         5109 a         3554 c         2124 g         7071 t
ORIGIN      
        1 attatcttat ttattggtat atgaaatcat attgtttatt attttataat cttttcatca
       61 tataaactat tgtattctat aaactgatac atatccagct gcagaagtac ctgtcgtgcc
      121 tgaaccaaat gtaaaactta aagtaacagc tgctgctcta gcatcaacta aaaagcttaa
      181 acttacactt acatctgatg aagtaagtgt atttactgct tttgcaataa agttattttg
      241 agctactcca ttaaagttag tagtaattga cataaatcct gcaagtgaaa gtgtggcacg
      301 tataccgaaa gatacattgt atatccctcc aactgcaaga tttatagtac tacttgttgg
      361 aaaagttata ttagttccat ttataaatga tgaattaaat gtcactaatg tattattcac
      421 taaacttgaa gaggacactg taaattgtgc attgtttgct gctaacactc ctgttgctcc
      481 tgtcgctccg gttggacctg ttgctccatt tgctcctgtt gctccggtcg cccctgttgc
      541 tcctgtcgct ccatttgctc cagttgggcc tgttggtcct atcgctcctg ctactccatt
      601 tgctcccgtt gctcctactg ctcctgttgg gcctgttgct ccatttgccc ctgttgctcc
      661 tgtcgctccg gttgctcctg ctactccatt ttctccggtt ggaccggttg gacctattgg
      721 acctgctact ccattcgctc cggttgctcc tactgctccc gttgggcctg ttgctccatt
      781 tgcccctgtt gctcctgtcg ctcctgttgg acctactgct ccatctgctc ccgttgggcc
      841 tgttgctcct actgctccgg ttggacctat tgccccagct actcctgttg ctcctgtcgc
      901 tcctgttgga cctaccaaac catttgctcc ggttgctccg gttgggcctg ttgggcctac
      961 caaaccattt gctccggttg ctccagttgg gcctgttggg cctgttggac ctaccaaacc
     1021 atctggacct gttgctccta ctgctcctgt tggacctacc tctccatctg ctccggttgg
     1081 acctgttgct cctattgggc ctgttgcccc agttgttccg gttgctccag tcgctcctat
     1141 acttccggtt ggacctgttg ctcctgtatt tcctgttggt cctgtagcac ctgttactcc
     1201 atttgctccg gttgctcctg tatttcctgt tggacctgtt attccatttg ctccggttgc
     1261 tccggttgct cctgttagtc cggttggacc tgttgctcca gttgctcctg tattccctgt
     1321 tggacctgtt attccatttg ctccagtcgc tcctgtattt cctgttggtc ctgtagagcc
     1381 tgttattcca tttgctccag ttgctccttt gtttcctgtt ggacctgtta ttccatttgc
     1441 tccggttgct cctgtattcc ctgtcggacc tgttattcca ttcgctccag tcgctcctgt
     1501 atttcctgtt ggtcctgtag agcctgttgt tccatttggt ccagtcgctc ccatatttcc
     1561 tgttggacct gttattccat tcgctccggt tgctcccgta tttcctgttg gacctgttat
     1621 tccatttgct ccggtcgctc cagttgcacc tctaggcccc gtcggtcctg ttggaccagt
     1681 agcacctgtt ggccctgttg gacctacatc ttgatataaa cttggacctg aaatatcact
     1741 catataatta atcctccttt tttaaagtta aagtattact ctataaatat tgagtattac
     1801 tctatataat tatatgaatc gacaatttct tatgtgataa tgtatctatt tgcttatatc
     1861 aacatatatg ctttgattct tgaatttcat tacttttttg taaaatcttt tacaattatt
     1921 agtactcttt tacaattact aatacaatta aaaaactcat ttcccatcaa ttatttaaaa
     1981 tttttttatt atgttataaa aaatagataa ttaaattgca taaaattaat ttaatactac
     2041 tttaattact ttgtaaataa aaaaacctca acacgattaa taaaaatcat attaaggcat
     2101 ccacaaaatt atataattgc ttatctatct tcatcagtaa cattgaatat ataaggaaca
     2161 tttctataat aatcaccaaa atcaaaccca tatccaacca caaacttatc ttctatttca
     2221 aatccacaat aatctggcac taaatcgact tttcttctgc ttggtttatc caaaagaaca
     2281 cagcatttta aactagcagg atttttagct tttagatgtt ttaacacaaa atccatagta
     2341 agtgcagaat cagtaatatc gtctacaacc aaaacatcat atcctgctat atcagtagtc
     2401 acatctgaaa ctactttaac ccttccagta ctttcttcat tgtttccata actagatgta
     2461 gtcataaaat taactctaag tggtaaattt atatgtctaa ctaagtctgc acaaaatata
     2521 aagctacctt ttaatagaga aactaccata agatttttat ctttataatc tttttctata
     2581 attgctccta attcccttaa tttatcttta attttttctt ctgaatacaa tacttcccat
     2641 ttttttgttt ctatatccat aaaaagacct ccaattgtaa taatccttct taattttata
     2701 agagattgct cactttttca atactcttat tcaatattag tcaatattat tgagttttta
     2761 tgttcattca acaattatta acaatgtatc ttatatttta agtagttcat atatccacac
     2821 taaattacat actatatatt ttagacaaaa aaagaaaaaa cttgcactaa caagtttttt
     2881 ctattataca taaatttata cataatcata ttttattaga gggtactaat taaatttatt
     2941 tatgctattt ttgttatacc tcataataca aaacatatta taaagtacta gtcaacttta
     3001 ttcatatcat tcattacatt taagattatc tcatctgtta tagacatacc tttgtcactt
     3061 actctaccta agttttgtat actttgctca acacttgaac caactatacc atttagtggt
     3121 ggtacaaaac aatcttgctt agctattata gcactttgta tagctgcaga tgctgcagaa
     3181 gataatttta atgcacagcc agctttcgca ccgtcacata tcattccact taagtcagct
     3241 atcatatttt ctatagctcc ttctatttgc ttttcagtac cattcataag ccaagagata
     3301 ccagcagttg ctccagtaga agcagcaaca ccacatccac atacagcaga taatcttcct
     3361 gtatagttct taatataacc agttactaga tgagatatag ctaaagcttt tgctagtctt
     3421 tcatcagatt gtgggaattt tttattataa gcaacgattg gaagaattgc tgttaatcca
     3481 tgatttccac tcccatttga actcataaca ggcattttta cccctgccat tcttgcatct
     3541 gaagctccag cagttaacat cattgcataa tttataacat cattacctaa aagaccttct
     3601 tctatagact ttttaattcc atatccgaca ccaataccag ttttttgttt taatccatat
     3661 tcagccatct cttcattcat ttttactcca tctagtaaaa attctatatc tttaaaatca
     3721 attccttcta cattttttat taattcttgt atagttactg tatccattaa actttcagct
     3781 ttttctgcca catcatttga agctgatact tttggctcat tgtctaataa tacttctcca
     3841 tctttttcta agaacgtaaa attatcatgt ttagttctta ttctcacttt agcaatatga
     3901 ttttttcctt ttaacacaac ttctataaat actttctctc ttgtatcagc aggtgttatt
     3961 gatagtggag tattatccat ataatcctca gctattttaa cttcctcttt tgttagagtt
     4021 tctaacacac ttaatccatt ttcagaatgt ccacctacta tacctagagc tgctgcaatt
     4081 tttaatccta atctttcagt acctggtata cctacgcaca taccattttt ataaatacta
     4141 ggactaacta acatacgatt ttcaactatt tcttctccta ataattcctt tgcctttgca
     4201 catgctagag ctaaggctac tggttcagta caccctactg ctggtttaac ttctgccttt
     4261 aacatttcca ctaattcttt tcttatatct ctcattatat ataaacctcc caattaagtt
     4321 tagatttagt actcaaataa ttaattaaat aatttcttat ctatatttat agcaaaatac
     4381 atgccatatt ttttatatct ttttatattt ttagtcttat attctataac cattggtatg
     4441 actgcttcta tttatgtatt ttttttattt acatagagta tttatattct ttaaaatgga
     4501 gaaacatatg acaatttcgc aaaaagacaa aaaaaagtct caaaatgaga ttctatatca
     4561 ttttgagacg gctcaaatat attatttttt aacttataaa aaacattttt taattcataa
     4621 aaaaagattc tgcaaaacac ttatagtata agtttaaagc tttctttaaa gttatgaatt
     4681 tagaaaaatt caaattttat atagcttttt attatattac tatgaaatta tattgtattt
     4741 ttcaattttt ctatataatg tagctcttga tattccaagt gctttagctg ttaattcttt
     4801 atctttttta taatctttgt acttatttaa agcttttatt atctcaatct tctctagttc
     4861 atcaagtgga attatcctat cgcttttaac ttctaactct tctacagagg tattcttaat
     4921 tttttgagga attacattca ttgtgattat tgaagaagaa gacatattca cactatattc
     4981 aataatattc tgcaactctc ttatattccc tggccactta tattccatca tagcatcaac
     5041 aaccctgcta tctatgtcaa taacattttt atctaatttt tttgaatact ctttaaccat
     5101 atgcttgatt ataagtggga tatcttcttt tctctctctt aaacttggta attttatagg
     5161 tataacattt aatctatagt ataaatcttc tctaaaagtg ccattttgaa ccattttttc
     5221 taaatcttta tttgtagcag caataattct tacatctatt gaaacatttg atttacttcc
     5281 aattttatta agttcctttt cttgtaatac tctcaataac tttgactgta aatgcaaact
     5341 catatctcct atttcatcta aaaatatact tcccttatga gctacttcaa acattccaag
     5401 ctttccacct tttttagctc cagtaaaagc tccctcttca tatccaaata attcactctc
     5461 taataaattg tctggtatag cagcacagtt tacagctata aaaggattat ctactctatt
     5521 gctatggttg tgtatggctc ttgcaaatag ctccttaccc gttccacttt ccccagtaat
     5581 aagtactgtt gatgttgatt tagaagctat tagggcttcc tttttagaat ttcttatagc
     5641 tacactttct ccaattatgt tttccaattt tattctataa tctttattca tcttattgta
     5701 gttttttata gcatctctct tatctataaa atcaataaca tatcccttta actcattttt
     5761 taatactatt ttattgatgt tgtatattcc cttcgaatca tatccgtatc ttttataaaa
     5821 aaaactacag gatttgtcct tcttaaagtt atttatagaa ggtttcttta taaaatctaa
     5881 ttcgacaaat atgtttttgc cagttatact atcttttata ttgaaaagct ctttaaattt
     5941 tgaattatat ttatcaattt ttccatccac atcaatagac acaacagctt tgtccatatt
     6001 gtttaatagt gtctctaatt ttttcttttc taattcaagc tcataagttt taatttgtgc
     6061 ttttaattta ttagatatta ggtctgccat tttgcctaaa aagtttataa gaccactttt
     6121 attattttct ataatttgtg cttgttcttt tgtaaaggct ataaggccta taacaccatg
     6181 agaatcgcca tcacatataa taggacaaca cacctctgca aactctacac aagccccact
     6241 tttatagcat tccctacata tatcactact ctttgggtca tcaattagta ttgtaatctg
     6301 ttctgtaagt gattttttaa aagccgtata tttatctact ttctcaccta ttttgtctat
     6361 atatactcct gtacctgcaa tcctaaataa ctccttattt actatagtta catctatatt
     6421 gagtactgat actatagctt cagctatatt ttgaatatca gattttatat attctaaacc
     6481 tatcataatc atcattcctt atttttcttt agcataagta tttgtcttat ttctttaaga
     6541 atcaagtata tcttatttaa agtaaattgg attgacatca ggattacaaa gagcataaca
     6601 attattatta actcataatt tatttccatc taaacatctc cttataacaa aagactaggc
     6661 ttaacctagt cttttatatt atatccatat ttatatttta actcatttat cttctttttc
     6721 ccacataaat atattttaat ttatttgact ctttaatcat accatcaaag tttaatcttg
     6781 aaaatatatt aaatacttca tgtggatagt gaatctttgc aacagaacca caaaatttat
     6841 gtttaagata gtttaactta acttttaaat tttttaaatt taaatcctct aatataacct
     6901 ctccattgcc ctttaacact ctttgtattt cagatgaagc tttttcacaa tctgtaataa
     6961 cattaaattg gtcaactatt attatcttgt tgaactgatt atcatcaaat ggtagaaact
     7021 ctaacttacc tttaactaca ttgcaatttt cattatacac tagagaataa cagacatctt
     7081 cataattact attctccagt atagttacag aagttccaag acctctcaat ctcttgccta
     7141 ggtttcctat atgaccaaca agcaatattt tatcacctac attatactca attgtatcca
     7201 aaaaacattc taattcatca gatgtatatt tagctttaac cggctgttta tttatctgac
     7261 ataatatgct tttcacaatg cttcacctct tcatttcctc aattataaat tatgtacaga
     7321 ttacattata ataaatggcg agcaactatt caagagatat ttcattagta tttttttaaa
     7381 caatctttat acattttaat atgatattat accaaattta ttaggatttt attcataaaa
     7441 atcagtctat tttttatgtt tattcattgt tattttcatc caattttttt attttcgata
     7501 tggatacttc atatgccatt tttttgacca cattattttc atctattttt ttctcatatt
     7561 ctctactttg aaccctaccc caaagctgta ttctatcacc aacctttaga ttctttgcaa
     7621 atttagcatt tctaccccaa actattgatg gtatataatc agatttatta taaggtctat
     7681 ttatagcaac taataaatcg gttatttccc ttcctaaagg tgtcttccta tacacaggtt
     7741 ccttacatac atatccatct aaaaatatac tattagggtc tttattttcc tcgtctatgc
     7801 tttttatttc tctgacaaac actgtaagca ctaatctatt tttattattt aatgttttgt
     7861 tatatgatct taattggcct acgacattga ctaaattttg tttatcaagg tcaatatctt
     7921 ggagaagtct ttctgataca gtcattggaa gtatatcaaa agaatcgctt agtctgttta
     7981 tttttatttt catattataa aatttttctc caaatatctc atggctaaat tctagcttat
     8041 tgtctaactc ccctcttaag tttactacgt tattctcatc tttaacagct atcatatttt
     8101 atccctccac aattgttaat tcttatattt ctggtatcag cttatataat aaatatattt
     8161 ataagggatg tattttatta caaatctttg attgctgttc aaaagttttt atttagttat
     8221 aaatttcatt taatatttca cttttataat tataaaatta ttatcttttt gtaccacata
     8281 tactaattaa actacctatt tcagttttgt attaattata aaaatcctat tatatagtta
     8341 ataagtcata tataacttaa atttattcac tctatataag caacttcaac gaattaaatt
     8401 tattcaaata attcagatga atattgagtc attataaact tatttttctt aattataagt
     8461 tatattagac ttattacagg ttatattttt attaatctgt attaatatat gaacatttat
     8521 tgaacttatt gattataaaa tttaaatatt tagctttaaa ttatgcttta ttctttaaaa
     8581 atacaacgtt ttttacatta aatctactaa atcactatat atattacata attggcatgt
     8641 taattgcttt atattaattt agtaaataaa aaactgccct aaaatattaa ttcaatattt
     8701 taaagcagtt tataatcttt attattagct gtaatattta ataaacacta agtagtcttt
     8761 aactaagcag tctttttgtt tttatttgca gccattatca ttgtagcaga agtataagct
     8821 ataactacta ttactaatgc ttttaatata tccattggta gagtttttac tatatatgca
     8881 gctacgaaaa ctcctattaa accacatata gctattataa ctgatgcttt tttagtatat
     8941 gcatcttctt ttatgaattt catacttgca actggcatta ataatgcaca agaacccata
     9001 actattggga atgcaacttt tgcagacatt cctaagaaat aaaccattgc catacctgga
     9061 gcatatagac ctataccagc tgtcattaaa gctcctagta taaagttacc tattacacct
     9121 attactaatt taacaccagt aagacctaat tcatttcctc cacctggtaa tacgttaatc
     9181 caaggatgac ctaataacat taatattgct gttaatgcta aagttacacc cataacaagt
     9241 tgtatttttc tctcgtccat cttagctatt attcctgcac ctatatatga accaactgct
     9301 gctgccacaa ccatagatac taaagtaaca ccatcaactg gtatgattga tgtaaatatg
     9361 aatgcttctg taacaactgg aatagtatgt gctacgttta atgtaccagg cattttttta
     9421 tctggtatat ttaactttaa agcctttgac attgctattg ttggagcaaa tgaccctatt
     9481 cctaatgtat caaagaagtc tgttataaat cctgttacag caacttttgg agtactttgt
     9541 tcttctagtt tcccctcttt gtttgcttta gctacgtctt taccaaacac aactgcaaag
     9601 attgctgcga atactacata taatgccttt aagattgcta ccataatcca tcctcctatt
     9661 tttttatttt ttcatatatt ctgaatctta tagcctaaaa gctatagaat agcaaccgac
     9721 aagtggctac tattctattt taatttccta atttatttat tacttattta agaataaatc
     9781 catgtttaag tgggtcttct tcatctatta caaaatgatt aaatccagtt atataagcag
     9841 aaccagttat tttaggtact acagcattga aatctgcaac tttagtttct tcaactattt
     9901 cacctttgaa taaagttcct aatatacttt catatacgaa tttttctcct acttttaatt
     9961 cacctttagc atgtaaagta gctaatttag cacttgttcc agttccacat ggagatctgt
    10021 caacttgacc ttgaccaaat ataactacat ttttgtaagt agcttctgga tgagttggct
    10081 catcatatat ttcaactaag tctacagttt ttatatgagc taaagttgga tgttgtattt
    10141 ctattttctc atttattata tctctaagtt tcatagctag ttcagttaat ttaccagcat
    10201 tttgaggttc gatttttaaa cctaattgac ttgcatgtat tatagcaaag aagcttccac
    10261 caaatgatat gtcaaattta acagttccaa cacctggtaa gtcaacttca acaccttctt
    10321 tatataagaa agctggtacg tttaagaatg atacttcttt agcttttcca tctacaactg
    10381 taacgtctcc tcttattatt cctgctggag cttccataac tacatgagtt acaggctcta
    10441 ctgctggaac tacacctgtt tctatagctg ctgtcatagc tcctattgta ccatggccac
    10501 acatgttaag gtatccgcca ccatccatga agattattcc aaagtcagca tctgggcaac
    10561 aaggttgagt cattacagaa ccaaacatat cattatgtcc tcttggctct aacattatag
    10621 cagttcttaa ataatctaga ttttcctcta aatattcttt tttctcaggc atagaatttc
    10681 cttttatgtt aggtattcca cctacaacta ttctagttgc ttcacctgct gtatgagagt
    10741 ctatagcttg tatacttctg ctaaatttca tatcaaattc ccccttaggt ttattttgcg
    10801 tctttacgca tttttaattt taggaaagcc aatgcttttt taacatcaac ttcgtccatg
    10861 tgattgtctc caactacttc tgtttctatg tagcctgttg tctttttata atcaattatg
    10921 gtagctttat ccaaatatgg attggtaatt actaatccat ctgctcccat aatagtaaga
    10981 cctactgtag gtatatctga ttttacaaac tctgctatag catttgtaaa atcaatgtgc
    11041 tggtttcctg ccatatctaa agttataatc actccatcag gtcgcaatga ttcaatccat
    11101 cttccaagtc tagttgctaa aaatgttttc cattcattgt gctctgatgt cccaactaca
    11161 accactccta acaagtctat gtcagaatca ttatctatca aatctagtaa cgggtctcta
    11221 aatatatgaa gtgatgtgtt tttcattgat gtagaaattc ccacaaaact cattccctta
    11281 cttaaatttt ttatccatgt tttctcattt taagttttaa aaatgccaaa gcttttttag
    11341 catctatttc atttgtgttg ttttctccaa ctacttctgt ctcaatacct tcttttgatt
    11401 tgttcatatc aactatggta tccatatatt gattgcttac aacaaactta gcttgagtcc
    11461 cattaaatgt aactccaact acaggtatat ctctttttcc tatttcctca aatgtgttag
    11521 cgtagtcaac atgtgagttt ccccaaccat ctgatgaaac tatagctcca tctactctca
    11581 tggcttccag ccaagcggcc gttctttgtc ccacaaaggt tttattttca tttccatctg
    11641 gagttcctac tactattact ccaagtaaat ctacatcctt atcactttca actatgtcta
    11701 aaagtgggtc tctaaagtga tgaagagatg tttcttttgt tgaaggtcct attcccataa
    11761 tatccacctc tcttaagtca tagctctaag ggcaccatct ctgtattcat taggagatat
    11821 aatcataggt acatttccca tatctataat tgatgttcct ccttcaaatc cactaggttc
    11881 ctttgagaat aactgattgt catacatagc accttgacct gctatttgtt ttactatgac
    11941 aacctttttt gcatttggtc gaattttgtc aaaatattca cgaacttgag tagcatttct
    12001 tccgtcttcc attttcaaag atgctcttat ttcttgtata aaatcatcac atgctctgaa
    12061 tgctgcaagt ggaagtgttc tttcaaaagg taaacctccc tttaaagtta catctacatg
    12121 gattatataa tcttcaactg atggagttcc atatctccca aataccattt ggtctttcaa
    12181 aattccttct gaagaaccaa attcatgcat ttgatttcca tcttcatctg caccagttaa
    12241 cattacatat acacccgtta aagtatgtgt aataccctct cccagtctgc ctaaaacttt
    12301 tgttgatatt ggtataatgt ccataatagt attaatttct ctgtcataat ctccaggttt
    12361 tataatgtct acttttatgt ctgttattaa ctcttctctt tcttttattt catctatact
    12421 tgataaatct attgtaagta catctttctt tatagaagtt tttgaaccga aattaacttc
    12481 attcatatga aacggtttta taacaagtct tctcattatt ttttcttcca taatatccac
    12541 ctttgttctt aaaacccctc tcctaaccgt gtaggagaag ggttctatat tttcaaatat
    12601 aaattacatt ttaaacgtga gctttatatt cgtatggtaa tggaactatc ttaccagcag
    12661 atggtattgc aactaattgc tctaatgtat ctcttaatat atgtgtttgc atttctatat
    12721 tatgtggttc accagcatta gcacccattg gaactaatgg agcaactgct ctaggagttc
    12781 cgttttgtct aactactgga ggaagagctg ctattattat tgtaggtatt ccagcttcct
    12841 ctattgctct ctgcacgatc acggcagttc tatggcaagt acctcagcca gctgtcataa
    12901 ctacaccgtc tactccctct tccttaagtt tagcagcgat agcaggacca gtttcttcag
    12961 tgaagacatg ttggtttcct ccaccaccca tgaatgcata gtgcatagga gctactcctt
    13021 tgataaatcc ttctgcagct aattcatgta atctatctat agggaacata cagtttatat
    13081 ctttgtttac atctccattg tcatatccac catgtgatac catcatttca tcaactgtag
    13141 ctgtattagg tatagctcta aatgtagtat ctcctgctag attaaatctc ttgtcagatt
    13201 ttaaatgaac accagctgct gtagctaaag ctatagtcat atcttttaat tctttagtta
    13261 caggagtcca aactggagga ggtgttattg gaacgaatat ttcagattga agtccttgta
    13321 ctgttgtaag gctcatatat ttcctctccc ttctattttc aaacgattat ttattatttt
    13381 tcttcttgtt ttgattgcat ttctgcttgt ttttcttttt ctctcctaat attttctaca
    13441 tactcttgat taggctctgg acttaatacc tcaggatagc ttagcatgaa tccaacttct
    13501 tgacctatct taagttcgta gtcagttata agcattctat taggtatttt aaattgtcca
    13561 agtctacctt ttaggtctat agtcactcca ccgcctttga tgtcaactat aataccttca
    13621 taaaaagtct ctgatgagat atattttaac ctatccatta taattctacc tctctatact
    13681 gttttaaact tggatctaaa tttatgttat tgtctaaatc ttagttagta tctaaatttt
    13741 agttttcgtc tttttcgtat atttctcttc tcttcttact cattggtaga gattgctcat
    13801 tctcttctaa tactattttt tctcctgtaa ctttttctat agcttctatg ttatttaatt
    13861 taacatttgg attccatttt ctttcaggag ctttaacttc tacaccttct atagcatttt
    13921 taagcatagc cattattcta acagcatctt ctggagctaa agtgttgtta gataatattt
    13981 cattctctat accttgctta gacttattgt tgtctaccat gtgagtcatg tatttattac
    14041 caacaactag agcaccttga acagctgaga aacttacacc aactactggt atacctctca
    14101 tacctatttg ctctatgtga gatgcgaaat ctatatggtt gtttccgaaa ccttcagtag
    14161 ttactacagc tccatcaact tccatagctt caactaacat acctaatctc ttagatacat
    14221 agaatttctc agcatttact tgtggagaac caacaaatac aacacctact aaatctattt
    14281 cttcgtcttc catagctctt attactaatg gctctctcca gtaatgtctt gacatttctt
    14341 ttgatgcagg tcctatacaa gttaatgcat ggataccacc atctaatact tcaagtggag
    14401 ataatacaac tggcatgttt cctaagtcaa cgtttggttg agctcctaat gtaccaactg
    14461 gctcaactgg taatattagg ttatcatgca ttgcaccttg tcccattatt tcttttataa
    14521 caacaacttt ctttttacct tctcttctgt attgctctat tacttcttca tcaactacta
    14581 aagagttgtc aactttcttt aatgcttctc ttatttcttg agttacatag tcaaatgcac
    14641 ggtgagcagc taaaggtcct ggtctttcca tgttagttcc tgcttttatt gttacttgac
    14701 ctttgatgaa tatttcacct ttgtcagcag cacctggtct accccacatt atagtagtat
    14761 ttaactcacc ttctgaagaa ccaaattcac ctatttgaac tccatcttca tctgtaccag
    14821 ttaataccat tacagctcca tctataactc tagttatacc tgaacctaat tcgccttctt
    14881 ctttagtagc gattggttgt atatctaata cagcttcact gtaagtttca tatttatcag
    14941 gagttattat ttctaacttc atatctacaa ctaactcttg agtttcatta gcttctttac
    15001 atatttcttc tgcgtttctg atgtataaag tagttccttc tattttagtt tcatcagcaa
    15061 attcaacttt atctatttta aagtgttttt tagttaagct tcttaaaagt ttcttttctt
    15121 caacttttgg agctacttct gctgctgcac ttgccactgg agcagcaacg tttgctactg
    15181 gagcagcaac tcctgcttga ccagctactg ataaaggtat ctctaagctt atgttcttac
    15241 cttcacctat gtgtatttta actgtttcac ctgcaactcc tgtgcttact ggaactactg
    15301 ctgcttctga tactggagct gcttcttcta ctgtttcttc tactacttct tctttagcct
    15361 ctcctgcttt gtatccttct acgttatctg tagtcattgg agaaagtgca tctaaagttt
    15421 cttttaactt agctcctagt acttgaccta tagttaatcc attttctggt attgttaata
    15481 atccagaatc ctctaagtct gcaaatattg ctggatcttc taagttttct ggcgctataa
    15541 ttgttcccgc ttcaaatcta caacaacaaa ctgctgggtc atttgcatgg gcttgagctg
    15601 tttctaaagt tattgacata gtataaaata cctccttaca ttattttctt atttattatt
    15661 ttaaatctca attcctcaac aggtaacccc ttaactgaga aattaagtaa attaaaacct
    15721 acataatttg ttatgattaa tattattttt ttctcactta aagtcacttt atattataag
    15781 caattcctat gccaacttat taacaaaaag attttttcta taatagattc ttcatctatc
    15841 gctattttta gccaaatatt atataaatat ttatttaaaa tatgttattt tttgtatttg
    15901 taaacatttt ctcaaacaaa aaaagtgtca attaatcaac actttttcat tttttttaac
    15961 acatctatat acacaacact tatacaagcg ttggctttac taggtttcaa attaaagttt
    16021 atcattttgt caaaatttag tcatgtgtca tattttagac acatctattt tgtattggtc
    16081 tatcttataa tacaaagttg ttctgggtat atttaatatc ttagctgctt tagctttatt
    16141 tccattagac attttaagtg ccttggttat attctttatt tcaatttttt gagttgcctt
    16201 cgttaaatct aaaggatact cttcttcttc agtactatta tttgtagaat ccatcatata
    16261 acttggtaca tcatccacat ctattttaga attttgtgac aatacaacaa tattttcaat
    16321 cgtatttttt aattctctaa tattaccttt ccatctataa ttctgaaata tatctattac
    16381 atctttgcta attgtaagaa caggcttatt attttgttta catatctcct ctaaaaagct
    16441 atgaaccaat aatcctatgt cttcttttct ctctctaagt ggaggaatct ttatttcaac
    16501 aacatttaat ctatagtata aatcttctct aaatttttct gcctttacca ttttactcaa
    16561 atctttattg gtagctgata ttattctagg atttattttt attgtggtat ctccaccaac
    16621 tcttcttatt tctttttcct gtaatactct aagcaacttt gcttgcatac taagaggtaa
    16681 atcggcaatt tcatctaaaa atacagttcc atcttttgca agttcaaata tacctattcg
    16741 acccttttta cttgctcctg taaatgcacc tgattcatac ccaaaaaact cactttcaaa
    16801 taactcattt ggtatggcac tacagttaac aggtataaat tgcccttttc tctcactata
    16861 atcatgaata gctcttgcaa atacttcttt acctgtacca ctttcgcccc aaataaatat
    16921 actactattt gttctagcca cttgttttgc aatcgctttc gatttttcca atttataact
    16981 tttacctaaa atcttatcaa aactaccttt agataaattt ttgacttcgt tctttagata
    17041 ttttaatgta tcatttactt tttcaagttc aagagctaat atcttagctt ctgtaacatc
    17101 aacttctgta catacaacac cgataaattc ttctttataa aatataggat ttgcatgaac
    17161 taatgcatac atattttctt ttttatctgt aaaatacaag tcactcattc caactttact
    17221 atttagtact ttttctgaaa tagtattttc caaaaattca ttcatcggtc gaccaactat
    17281 atcttcagac tttatatcat acctttcctc cataaactta ttccacaaga taacaacacc
    17341 ttcgttattt atagcacaaa ttccttcttt aatttgacct ataatatact tcaaagtcaa
    17401 tccataatct tctaaatgca tatatagata gtccctaatg tgctcttgtt ttagaactcc
    17461 aataatttta ttatctctaa gaacaggaag aatccctata ttttttaata tcattatatc
    17521 tctacattca tctaaggtta aaccttcgtt gacatatatt acatccttct tcattataag
    17581 ttttactggt tgaccttcat actttttatg catctcataa agattatgta tatccgtcat
    17641 ggatataatg ccttttaatt ggtcagatga atctattacc attagagttt ttgtgttgct
    17701 ttttatcatt tcttttattg catcttcaat tcttgtgtct tcgtctatag ttgtaaattt
    17761 tgtatccatt acctcttcta ctttttttac ttctggtatc gaaaacataa agtcccccct
    17821 ttatagtagt acctcatcaa aacttattta tatatatt
//
LOCUS       DAEPXW010000081        17789 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.082, whole genome shotgun sequence.
ACCESSION   DAEPXW010000081 DAEPXW010000000
VERSION     DAEPXW010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17789
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.082"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(101..1315)
                     /gene="dpaL"
                     /locus_tag="KRM55_002714"
     CDS             complement(101..1315)
                     /gene="dpaL"
                     /locus_tag="KRM55_002714"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH1594936.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            complement(1938..2475)
                     /locus_tag="KRM55_002715"
                     /pseudo
     CDS             complement(1938..2475)
                     /locus_tag="KRM55_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            complement(2552..4357)
                     /locus_tag="KRM55_002716"
     CDS             complement(2552..4357)
                     /locus_tag="KRM55_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1594937.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            complement(4753..5130)
                     /locus_tag="KRM55_002717"
     CDS             complement(4753..5130)
                     /locus_tag="KRM55_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH1594938.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            6035..6520
                     /locus_tag="KRM55_002718"
     CDS             6035..6520
                     /locus_tag="KRM55_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594939.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            complement(6720..7259)
                     /locus_tag="KRM55_002719"
     CDS             complement(6720..7259)
                     /locus_tag="KRM55_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1594940.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(7252..7665)
                     /locus_tag="KRM55_002720"
     CDS             complement(7252..7665)
                     /locus_tag="KRM55_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1594941.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            complement(7701..8822)
                     /locus_tag="KRM55_002721"
     CDS             complement(7701..8822)
                     /locus_tag="KRM55_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH1594942.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNIEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILIPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            9421..11073
                     /locus_tag="KRM55_002722"
     CDS             9421..11073
                     /locus_tag="KRM55_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBH1594943.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            11372..12121
                     /locus_tag="KRM55_002723"
     CDS             11372..12121
                     /locus_tag="KRM55_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594944.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFGIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYVASFANRILIFKDG
                     HIIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            12134..14161
                     /locus_tag="KRM55_002724"
     CDS             12134..14161
                     /locus_tag="KRM55_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1594945.1"
                     /translation="MNIFYTAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFIIGLVLGALAHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAVSNGKFFYKTPLVKLIRYEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQNSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLVNGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTSILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYDNIQIKKIIKKQVLPFFNIPFLLGILDCIFAT
                     LVYKTALMQNLLGNSFSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKN"
     gene            14305..15888
                     /locus_tag="KRM55_002725"
     CDS             14305..15888
                     /locus_tag="KRM55_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1594946.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFITTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFF
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLI
                     SIKNMMSKSYRPDVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNISDNGVANTSFKTPLDITKITFDTTKHKGIISIKEQVENLGGTISVSDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            15860..16480
                     /locus_tag="KRM55_002726"
     CDS             15860..16480
                     /locus_tag="KRM55_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594947.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYKEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGGTCFPSENTEVIIEDLTTMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(16675..17601)
                     /locus_tag="KRM55_002727"
     CDS             complement(16675..17601)
                     /locus_tag="KRM55_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH1594948.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNNESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
BASE COUNT         6170 a         2757 c         2157 g         6705 t
ORIGIN      
        1 tgttttagtt tttattttat ttaaagtttt cacttattta agtttttatt ttccttaaat
       61 ttttcatttg tttattaagt ttttcttttc cttaagtctt ttatttactt tggcattcac
      121 cattccaaac tatatctcta tatttatcag ggtcagtatc tccttctgta cttattaata
      181 atactttaga gttctcatct agtttcaaag cttctcttaa gtcttttaaa tcttcacttt
      241 caaggattga aactaatgct ccagttgtaa ctgctccaga ttctccagag attactttct
      301 catctcctct tagagggttt cctaatattc tcataccttt agcagatacc cagtctggtg
      361 ctgaaacgaa tgctgatgaa taatttttta acacttcaaa acctatagtg tttggttctc
      421 cacaagcaag ccctgccatt atagttggca tatctcctcc aacaaatctt ggttttccat
      481 ctccagcttc tgctgattta tagtaacaat cagcctcatc agcctctact actactgtta
      541 ttgggcattc atcatatatt gaagcaacat acccttgaac tgcaccagca agtgaaccaa
      601 ctcctgcttg aacaaatacg tgtgttggtc tatctactcc atattctttt aattgttcta
      661 tagcttcttt agccatagtt ccatatcctt gcattatcca tgctggtatt tcttcatatc
      721 catcccatgc tgtatcttga accattactc catggtcatc agcttctgca taatcattag
      781 ctaatcttac tgcatcatca tagtttaagt ctgttatact agcatctgca ccttctcctt
      841 tgattttatt taatctaaat tcagaagaac cttttggcat taatacaaca gatttttgac
      901 ctaatttatt agctgtccaa gcaactcctc taccatgatt tccatctgtg gctgtaaaga
      961 aagttatttc tcctaatttt tcttttattt cttttgaagt taatttatca taccctaact
     1021 cagatatatc tgtatctaat ctttgagcta agtatctacc catagagtaa gaaccaccta
     1081 aaactttaaa tgcatttaaa ccaaatctat aagattcgtc tttaacatat attccgctta
     1141 cgcctagtga ttttgctaag ttatctaatt taactaaagg agtcttttca tattgtggaa
     1201 agctctcatg aaaagcttta gcctttgcaa tttcttcatc ttttaaaaat tcaattcctt
     1261 tttctttttc ctctgattta ggtaagttat ttaatttcca ttttatttct ctcatttatt
     1321 ttatattccc ctttcaaatt tttcggtgtc attttaattt tttatctttg tgccttatag
     1381 caaagcaatt accgtgccaa tattatttat tctaaaaaca atttttttat gttggaatta
     1441 catactttta taaaatttct ttaaagttta taaattttga gtgtgaaaaa taagatttat
     1501 aaaagaaaaa attctcatat tgggaaattt ttatcaatac gagaattatc aattcgagaa
     1561 atcgtttatt tatcttaatt cttcctttat tatgctctta ttttttatat atctattgtt
     1621 ttgtcagata tattactact tttattttct ataaatatat ggctataacc ttcttacgca
     1681 taaactctat aaatttatat actttatatt ctttattacc caaatattct ttattaccca
     1741 aagcctccaa aatggcttaa atcttttcat agcttcttac agaagtttac atgagcgtcc
     1801 ccccaataag caaaagtgca atatgtgtac cattgtgccc tacttgcgac tattgagctg
     1861 tcgaaattcg caacttcgca tttatctgat gaaatgcact atgcaaaata ttcataacat
     1921 ccacaacaga gttaaagtta cctattcata ttcactgtaa aaatttcttc cacaggaaat
     1981 gtaattttaa ccaatcctat tgagacaaac tcaccactta tttttttgaa ctcacgcagt
     2041 aatacatcac ttgcccgaaa aaaagcctca ctttcatcat ctccagtaag tgctattgtg
     2101 caatggggta cccaacgatt ggggtggtac cattcccaac catttgaatc aaaatcttgt
     2161 agtacctcat ataattctct ctgaaactga tacattgcta ttcattatag gtgatacaaa
     2221 caccgtttta gtatcattaa acatgcctac tgaaccaatg taagcaggta ttaccttatg
     2281 gttttgtgca aaccccttta gcttgtctat gcaacaagcc tcatccacat cattgaaaca
     2341 agccaaagta agatgaggtc ttgttttcca ttctaagtac ttcgtactaa ttttttcatc
     2401 agcgattttt ttagataaat caaaaagttg cttttccgtt tttttatcat aatatagctc
     2461 tatcgcatat tgcataataa cacctccacc ataaagtaaa aatacctatc tataaaaaca
     2521 cacaaatacc tatcatttta atattatatt actactgttc ctcttccaat tttctatata
     2581 gtgtagccaa acctatgcct aagtcttttg ctatcttctt cttcgtcttt gtatctcttc
     2641 catacttatt caacaacttg tttatgtaag tcaactctaa ttctttaatt gaaagtatcc
     2701 tttcttgatt ctctactatc cctccaacta tatcatcttc aaatattata tttacatcct
     2761 tatttttata aatatttcca ttaatattat aatagtttaa aatatctaat ggaagcatat
     2821 ctttatatat tattccatca tctccaacca aattcatcat atattcaact gcattttcca
     2881 gttcccttat atttcccggc caattatagt taatcaacat attcattaca ttttcttcta
     2941 ttttatttaa ctgaatacct aattctaaag aatatttaga agcaaacttc atcattattg
     3001 cctcaatatc atcctttctt tccctaagag gtggcaaatt tataggaatt acattcaatc
     3061 tatagtataa atcatcccta aacttacctt catttactaa tttcaataag tttttatttg
     3121 tagcagcaat cactcttata tctaaatcta taagtttatt tgacccaatt ctcgcaaatt
     3181 ttctctcttg taaaactcta agtaactttg cttgtaaagg cattgacaaa tctcctattt
     3241 catcaagaaa tataacacct tcatttgcaa gttcaaattt acctacttta cctccactac
     3301 tagctccact aaatgcacct tttatatagc caaatagctc actttcaagg agattttctg
     3361 gaatagcagc acagtttatc gcaataaatg gcttgttcca tctgctacct tcagcatgta
     3421 tagccctagc aattagctct ttacccgtac cactttcccc agttataagt acagttgaat
     3481 ttgactttgc taatttctta gttctctctt ttacttttaa cattgcttct gaatttccaa
     3541 ttatagactc tatatcacta tttccccagc cactattcac ttttccatgt cctttatgat
     3601 tgatatatgt cttgtcaaat attattattt tgtcgtattg atttatatat ggatataccg
     3661 gaattatttt ggcatttata ttataaattt tgttatcaat atcaatttct agtaattcat
     3721 gtccatttga ggaagattca acagatacta tatttactat attttctatt atatttttat
     3781 ctatatctaa tttttttaga gctatattgt ttatataaga tattttgcta tttatgtcta
     3841 gtattataac gcctttttca acattttcaa tgatttctat catcatatcc atttttctac
     3901 tgctattttt tgacgcttca tgttcttcta ttttcataga aattaaatcg catatatgat
     3961 tgacaaattt taaataatta tctatttttg cacttatttc tactttttta gttttatctg
     4021 tactaatagc accaattact cctatagttc gattattata ctttattgga actgctatta
     4081 ttactttatt taggcatttc atgtaatggg aacattctat acaaagctga ttatcacata
     4141 tatccaatac gactaattcc tgacctgtct gtataacatt gtcataaata aagccctcag
     4201 taacaacgct ttcatttatc tttgatttat acagacctgt accactaatt cttattaatc
     4261 tatcgtcaac tatttcaata tctacatcta acacactagc tactgtttca gtgtatttta
     4321 tcatttcttg ttgaaattct tttaatttac ttaacatagt ttcccccatt agaatttaat
     4381 ttaccaaatt atcagtttag ctatatttta acatatagtc actctttaaa atatatataa
     4441 aacattactt atttatatat ttgcgttaaa acagacaata ttaatttata aaaagtttgt
     4501 tttatatagt aaccttaatt ataatatgca gacaataaaa taaatcacaa tacaataata
     4561 aaaaaaagct ttcctcatat aacaaatata tttttgacat aaaaatatac attatatgag
     4621 aaaagctcaa tagttaaata tttagataga tttttatata gactttttta atataaactt
     4681 ttttaattgt agactttttt tattagtttt taatttttat tagttttgtt attggtttta
     4741 ttgttataat acttataata ctgccattgc ttcaatttct aaaactgcat cttttggtaa
     4801 ttgagcaact tgtacgcatg accttgctgg tggattttct ttaaaatatg tagcatatac
     4861 ttcattaata tcattaaaat cctttaaatc ttttacgaat actgtagtct taaatatttt
     4921 atccatactt gtaccagctt gttctaatat tgcttttaca ttatctaaag aagcttttgt
     4981 tgcttctttt gggtcagata ctaactcgcc agtcttcata tctattggaa gttgacctga
     5041 tgtagaaact atgtttccaa cttgaattgc ttgagaatat ggtccaattg ctcctggagc
     5101 tttctctgta gctattacta cttttgacat gacttcacct cctattatta agttatattt
     5161 acaggaaaat aaaatttcct aaacaccaat attaatacga acctttagat taaatttcaa
     5221 atctaaaact tcaaataatc aatacttaga tgattatgtt tatttgtgtc ttgttaactt
     5281 ttattaaagc aattaacgtg ccaaacttta tttatatata aaattttgtg aagtcattca
     5341 aaatagttac ttctgaattt tttcgtaaaa aaacgctcta aaattacttt tttatgatgt
     5401 caattttttt ctcatatcta gaaatttacc aacatgagaa ttcttgtttt gagaatttac
     5461 agattaaagt tattttttaa ccttaaattc tgaacctccc atgactaaag tcacagggtt
     5521 cctgcttcat agaattttgc ataatcaagt tattacatat gaaagaacta tagttgacaa
     5581 tcccactatt ataaataata aaacctttac ccatacctta tttaccctag ttatcataga
     5641 gcctattgaa aatataacag ctaaatataa taataaccaa aaaattatca atatctacca
     5701 ctgttgctga aaatccaaaa aactaccttt tgatagtatt acttaacaat ctaattaatc
     5761 tcataataaa tttacaactt ataaataaat tgttatattg gccgtatctc aacaactttc
     5821 tcctttccta gttttaaatc ttttatagaa ttgtaccacg tctaagtaaa ttttcatact
     5881 attaagtctt atttctaata aatcattagc tctcattcta tgcccaataa tgtaagattg
     5941 cagtaatttt attgatttta atagttttat ttaatatact tatattaatt attttcatat
     6001 gaaattatta tttatatagg gggatttttt taatatgagc aaaagtgagt taacagcaga
     6061 aacaacagaa gaaatgttag aagtactaag tggtaaagat tatgatattg catgtcattt
     6121 acatgaactt ggtaaatcat tagattgtaa aattgaacca aaaacaggtg ctcgttctta
     6181 caaaatagta tattcaacta agaaaccaaa acgtagctta tttactattg aatgtaatga
     6241 aaaaaaatgg agagttaaag caaatctttt tcatctaaat acatataaag atgctgtgga
     6301 ggaatgctct aaaactatta aagatagtat aactaaaact cgtacttgta agaaatgtaa
     6361 ttcaaagtgt attggaggtt cttcgtttga attagatgga aagtcttacc tgacttgcat
     6421 aggaagtggt cattattttg caaatatgga agaaatggat tggaaaaacc tagaaaaatt
     6481 aattactaaa gaaaataata ttatgcagga atctgtatag ttttttaagg gtaattatta
     6541 aaatatatga gcaacaacag atacttaaat aggcataaaa aaataaaggg tataataagg
     6601 atatagaata aaaataaatg atatagcaca aagaggctgt ctcaaaatac agataagcct
     6661 ctttttattg ttgaaatgat aataatatat tcaattttat acaattttat acaaacatac
     6721 tacgccaact tacccatttc atatgcctgt ttcattgcct tacttccctt aatatcacct
     6781 acattccaag cacctacacc atatactata cctttttcct tagaaccatt tagacatgat
     6841 gtaaatcctc taaatccttc tattgttctt tccatatcag ccacattttc atctgctgct
     6901 gtaacgataa aatagaaatc tttatcacaa atttcagtat atctagagca agttctatca
     6961 atcatagttt tcatttgcgc attcatagta taaaaataaa ctggagtcgc taaaacaatc
     7021 acatctgccc caatcatttt ttcaagaatt tctcccatgt catctgtctg tgaacaattt
     7081 gcttcttttt cataacaagc accacatcca gtacaatagt taatatcttt atcttttaaa
     7141 aatatcttct ccacttgatt tttagattct aatacccctt gtataaactg gtcacacaat
     7201 aaatcagaat ttccaccttt tctaggacta gctgatacta ttaatacatt tttactcata
     7261 agatactgcc tccattttct tatttctact gctctttaat actttttctt tctcaataat
     7321 accttcttca tatctatcaa tcttaaaatt taatcgttcc aaagtttttt gcatttcttc
     7381 tattcttttt gctagttggt ttctctgctc tattaaaagt tcttttctag ctttgatagt
     7441 actgctccct tgttgaaaca tagctacata ctcaattaat gtctcaatag aaagacctgc
     7501 acctctcata cactttatga aattaaccca ctcacaatct tcttctgtaa aagacctaat
     7561 tccactttta tttctattta caggtggtat taaaccaatt cgttcataat atcgtaaagt
     7621 atccgctgaa agctcgtatt ttttactaac ttctgaaatc gtcatacata tcttctcctc
     7681 ttgatattgt atagattgaa ttatttctca aaggtttctg ctacattctt taaagcatct
     7741 ataattttaa tgtgttgagg acagctttct tcacattgtt tacattcaat acaatctgag
     7801 gcctttccat aagttttagt ataattatta tagtagacca tctgtgttga aaatccagta
     7861 ttaagagctt gtttttctgc attgtacaac gcaaaatagt ttggaatagc gatatttttt
     7921 ggacagcctt ctacacaata ctgacaggca gtacaaggaa ttaaaattga ttcgttgata
     7981 atctctactg cttcatctat aatattatat tcctcttgta cgaatggttt gaaattttgc
     8041 atatatcctg tattgtctaa taattgttct atatttgaca tcccacttaa gaccatcata
     8101 acattatctt tacttgctgc aaaacgtatt gcccaagatg aaattgacat atctggattg
     8161 tagtcattca ataatttctc tgctttttct ggtatctttg caagtgtacc tccttttact
     8221 ggctccataa caattacagg cttattatgc ttctctgcca cctcgtagca ttttctagat
     8281 tgtatgcttt cattatccca atctaaataa ttaatctgta attgcacgaa gtctacttct
     8341 ggatgctcac tcaagacttt atccaataat tctgcactat catgaaaaga aaaaccaata
     8401 ttctttattt ttccttcttt tttcttttct tcaataaact taaagctatc aaatttttta
     8461 gctacttcat aatgtgacac gcctatattg tgtaaaagat agtagtcaaa atagtctaca
     8521 ccacattttt ctaattgctc attaaaaatg gtttcttgct cttctttttt ctttaaagcc
     8581 attaatggaa gttttgtagc tatagtaaaa ctctctcttt tgtgtctttt tactagagat
     8641 tctctaagtg ctatctcact ttttcccatg tgatacacat aggctgtatc aaaatatgta
     8701 aatccccttt ctaaaaaagt gtctaccatt ttatttaaat gttccatatc aatagttgta
     8761 acatcatttt catcttttat tggtaaacgc attaatccaa atcctaattt ttttgcctcc
     8821 attgttttac ttcccccttt aaaacttgtt tgttttttct ctctacttta actattctta
     8881 caagtatata attcttgtat aattatactt tactacttgg agttaacttc aagtcaatag
     8941 atttttttat ttttaagaca aatattataa aaatacagtt ctttaatatt aatccattac
     9001 atgtttcttt caccctccaa ttctcaaact tcacaaactc caacatgtaa agaaatatat
     9061 actttaagaa attcagtcca ttaatattac tacaaatact ttttagatat gtttaaaaag
     9121 aaatttcacc taaaatattt ataaaagatt tagaaatagg tcttgtgtct attttaaaat
     9181 atataaaaca gtgataaaga cttatttata agataaaaaa tgaatagtgt ataccctttt
     9241 taaaaagttt tttccttttt atatttgtga tacaatgtta aatataaaaa ggaaaatttt
     9301 gtattaaaga aatcttattt gttgattttg taacttcaaa ctcagtatca atttgatttt
     9361 aagattatat tttattaagt atgctaaata acaaattttt aaagattgtg aggtaaaaat
     9421 atgaataaaa aaaatttagc tatattaata tcaggtatga tgtttttttc tagttcttca
     9481 gcaatttttg cagacaatac tacaaagcaa gaaagattaa taggtaaaac aagatatgaa
     9541 acagcagtag aagtaagtaa attgggatgg gttcaatcaa aaacagccat tatagttaat
     9601 ggtaattcta ttcaaagtgc gctttgtgca aatccatttg ctaagctaaa gaatgcacct
     9661 atacttttag taaacaacaa cagtattgaa aattcaacta aggctgagct taaaaggctt
     9721 ggtgtagata atgtgtacat tgtagatagt ggaaatagca tttcttctaa agtagaaaat
     9781 gaaataaaat cacttaacat aaaaataaat aaaatagtag gaaacaatat atatgaaatg
     9841 tctacaaatg tacttaaaga aatagataag ataaaaaagg tagaaaatgt tgcagttgta
     9901 aatggactaa agggactatc tgatgcagtt agtatagctt ctccagcagc aatacataat
     9961 atgcctataa tattagtatc agatgaaaac agcaatgata gtagtataaa tttcttaaac
    10021 aataggtcta taaaaaaatc ttacatagtt ggaggaaata agattttatc agacaataca
    10081 gtaaagaaat atccaaacag agaaagaatc agtggttcag atagaaacaa tactaatgca
    10141 aaaattattg ataaatttta taaagataaa aaaataaata atgtatttgt agctaaagat
    10201 ggtattaacc aagaaaatgc attagtagat tcattatcaa taggagtact agctgctaaa
    10261 gaaaattctc ctataatgat atctaatggt agccttgtaa atagtcaaaa agaatttatt
    10321 aaaaataaag atatagatga aataacacaa gtaggaggag gatataatca aaaagcattt
    10381 gaagatattt taaaactaaa aaatgtgaac ataagaaata aaactaaaaa aatatcttta
    10441 atacaggcta aagaaatatt aaaacaagct cttccaggaa gcaatatttt agtttgttat
    10501 tatgatgaag atgataatga atatgactgc aaagttataa aggataatat cctatatgag
    10561 atagaaattg atgcctactc tggtaaaata atagaaattg aaaaagatga tgacttaaat
    10621 gataataatt taggtacaca aaatatatca ttggataaag ctaagtctat agcattagat
    10681 gctgttccta atggtaattt aatctattgt aaatatgatg ctgaagataa cgaatacgaa
    10741 gctaaagtaa taaaaaataa gaaaacatat gaattagaga taagtgcatt tgatggaaga
    10801 attgtagata ttgacatgga caatgattct gatgatgact ttgatgataa tgataagaat
    10861 aactctaata ctaatgacaa cagttctatt attagtgctg aaaaagctaa atcaataatg
    10921 ctagataaag tgcctggtgg gaaaatagta aaatttaaat atgatgaaga tgacaaagaa
    10981 tatgaaggtg aaataataaa aggaaaaact gaatatgaga taacaattaa tgcaattact
    11041 ggtaaaatat tagaatttga aatagatgat taataaaaaa tatatattct attaattatt
    11101 acaagcaata aagccataaa tattgaaatt ttcaatattt atggctttat tttatttttt
    11161 ttaatttaaa tccacattat gccattatat atatctatgc actcttttaa attaaaatct
    11221 tgtccatcat cccaaaccta ataaagttag attttaaaca atatattgtg atataagtaa
    11281 tttgtgtaga attattgcgt gatttactca tgaagaaaca ataaggttaa tatataattt
    11341 gactatatta agacaaaagg agacatatac aatgaataca atattaaaag taaataacat
    11401 aactaaaact tataataaag ggcaacagcc gagtttagat aaggtatcct ttaatgtatc
    11461 agaaggtgaa tttataggta taatgggagc ttctggctct gggaaaacaa ctctacttaa
    11521 tgtattatct acaattgata aaccaacaag tggagatatt ttcataaata atataaattt
    11581 gaaatcgctt aatgacactt gtgctgctga ttttcgtaag gataatttag gctttatctt
    11641 tcaagagtat tttttactag atagtcttac aattttcgag aatatttcag tacctcttac
    11701 acttcagaaa ctcaatccag ataaaataga aaacatggta aagagtctag ctgaacgatt
    11761 tggcatagct tctcaattaa ataaataccc aaatgaatta tctggtgggc aaagacagag
    11821 agcttcagca gttagagcaa tagtaaaaca tcctagtatt ctctttgcag atgaaccaac
    11881 aggagctttg gattctaatt cagctactga actactccac tcactacagg aagcaaatga
    11941 ggagttgaaa acaacaattt taatggtaac acatgatgcc tatgtagcaa gttttgcaaa
    12001 tagaattttg atttttaaag atggtcatat cattaaagaa ttaaataaac aacagaataa
    12061 tagacataca ttttatgagt tgattattca agaaattgca aaattggata ctaaaagata
    12121 ggaggataat ttaatgaaca ttttttatac ggcaataaag aatcttaaaa aaaacttttc
    12181 attctattct ctatatctac tttcagtctc ttttgttatt actgtatttt tcgcatttac
    12241 ttcattttct gttaataaga taatgctaga aaaaatttca actgatggta gagttgaatc
    12301 tatgtgtaat gttatttcga tatttttgat ggcatttgtc atcttctata tggcatactc
    12361 aaatcgattc ttcttgagac gtcgtacaaa agaattaggt atatatgctt tacttggcta
    12421 tcgtaagttt acaatattat cgctacttac ctttgaaaat gtattaattt gtagtggagc
    12481 ttttattatt ggattggtat taggagcatt ggcacataag ggtattgtct ttggaattac
    12541 agcactactt aatttatcaa ttgataattc acagatacca ttttttaata taaatgcaat
    12601 aaataaaaca attatcttta tagcattagt tgttttagtc ttagctgtat caaatggtaa
    12661 atttttttat aagactccac ttgtaaaatt gataagatat gaaaaaagtg cagaaaaaaa
    12721 attaaagttc agaaaaattc cagcctttat ggggtttatt atgattttaa gcgggtattg
    12781 tttatcacta gatattcttc gtggagctaa atcagtatgg gtaagtattg gattttatca
    12841 aatgggcttg ataactatga ttatcattgt aattggtaca gttctcttta tcaattcctt
    12901 tcttccatat attatgcaaa atagtaaaaa aaataaacgt actttctaca cagatatgaa
    12961 gataatagct attccaaact ttatctatcg tatacgttca aactctaaaa ctctaattat
    13021 gcttacatta ctctctgcta ctactttgac agtttcaagt gttatggcac tgtccttata
    13081 ctaccctatt gcatctgttt cgcgtattgc accttcagag atagaattta gagtagaaaa
    13141 aaataaacaa atagaagatg taaaacaaat tgtcagtcaa tatacgtcta atacagatga
    13201 tattattttt acacagacaa atatttataa ggtaaaatct tcatcaaaag accttccatt
    13261 tgaatatgaa attggtacat ctaagaataa tttatccaat agtagttctt ctaaagaagt
    13321 tatttcaaga gaatcaggat ttgaatgtat atctttttct gattattata ctttattaaa
    13381 ggcacaaaat cgaacaaagc tactaaaaca acttacccct ttaagggata atgaatgtat
    13441 tttaatgaaa tatcaaccaa ataatgatgg atatagtgaa aatggaacga tttatccatt
    13501 acttgttaat ggtaaagaaa cacctgtagc tgtaagggaa acatcattaa acaatgctat
    13561 ttcttttgcc aatagcgttg gaacacttat cgttaatgat agtatatatg agcaaatagc
    13621 acaaaataaa ttaccaatga caagcatttt aagtattaat ggtaaatcaa ttaaaaataa
    13681 tgaaaattta tatagtaata tttcagatta tttagatgga agcccttatt tacaaggata
    13741 ttctcacagg ataaatgatt tgttatcaat taatagttct acatttctgt taatcggatt
    13801 tcttgtggta ttattcttta ttgctgttgg aagtatttta tactttaaca atatatcagc
    13861 aatttcagat tcaacatctg attataagat tttacagaaa atgggttatg ataatataca
    13921 aattaaaaaa attattaaaa aacaagtatt gccatttttt aatattccgt ttttacttgg
    13981 tatattggac tgtatatttg ctaccttggt ttataagact gctttgatgc agaatttact
    14041 tggaaattca ttttcacaat acatacctgt gattattgca attttcttaa cttctgtagt
    14101 gtatttgata tattatatac ttactattaa atcctgttgt aaaattgtat taaaaaatta
    14161 atatttacca aatcgtcaag cttagaggtg tgacgatttg gtatacttca tttataagta
    14221 tttgatataa tttaaaatta tagattctta ggtttgattt agtcataaaa ttaatataat
    14281 taactcataa ggaggtgtat aagattgaca aattttaatt taaaaatact atttttagga
    14341 aactacattc tatcacttct cttcatggga atatctacaa gcactgaaac ttatatgaat
    14401 atccaaagca ttattccctt aataatttca acattattac tcatagacat cacatatata
    14461 acctcttgta atgtccgaga aaataacatt atttcattgt tttgtggatt actagcacta
    14521 gacagttggt atttactctt atcatttata accacaccaa taggcactat tatttttaaa
    14581 atattaagca cagttatagt gtatgtctct attaaattta tatttttatt tttgtttcaa
    14641 ggtagtggat acaatttccg taagataaca gacattttat tgcttatcac ctgcattggt
    14701 gcaattgtag gagcatttat ttctaacaga acgtatgctt gtatgtacgg aatacagttt
    14761 gttgttagta taataagctt tttctatatt attttttatc atttgaaaag ggttgttttt
    14821 gtcataaaaa gcgaaaaaaa acctatatcg atttcagtat ttataacaat tataggattc
    14881 cttacttatt atttttttac actaagaata tcaaatcata ttggtaattt tggaatctat
    14941 ctaactgtac tggtattttt tatgagtatt catggtattg cacttaaaga aaatgatagt
    15001 tttcctattt caacagtttt taacataaaa caaagggcta tatttctttt tataagtatt
    15061 ttagtaatta gcttggtcgt actatttgcc aatgggaatt tttctataat attaatagct
    15121 ataaatgttt tatttatgct cattttcctc tgtaacatta ttttggagtt taaccttaga
    15181 gatgaaaaaa ataaagtagt taaaaatagc aagtatactt ttgcattaga aaaattacaa
    15241 caagaagaac aactaaaaac agagttttct aattttttac atgatgacat attacagaac
    15301 ctgatttcaa taaaaaacat gatgagtaag tcatatcgcc cagatgttca agatattata
    15361 tatgaaacac ttaacaatct aaatacatgt ataaggaagc aaatgcaaga ctatcatcct
    15421 gttattttaa aaaatttaac agtaaaagaa aattatcaga atttaattga aagtgtttct
    15481 tcatcctttc cacaaaaaaa tatttgtgtt tcatttaagt gttctgatac tttattctta
    15541 gttgaaccat atgatatatt gatatatcga ctgattaaag aattattgac aaatgtgtat
    15601 aaacattcaa atggtagcca tgcatggata gctttagcac tagaaaaaaa tataataaaa
    15661 ttaaatatta gtgataatgg tgtggcaaat acatctttta aaacgccttt agatataact
    15721 aaaattactt ttgatacaac aaaacacaaa gggattatat caattaaaga acaagtagaa
    15781 aatctaggag gaacgataag tgtttctgat aatatacctc atggagtttg tgtacagatt
    15841 acaatcccta tgaaaggaga tggttcttat aaatattttg ttagttgatg accatatgct
    15901 ttttgctaaa agcttgtcaa ttgcactaga agaatacaaa gaaatcgaac agttttattc
    15961 cacacaggac atccataatc tttcagaaat gattcaagat aaaaaaatag acattgtctt
    16021 aatggatata aaccttagag gcttaagtga atgtgatggc ttaaaagtag cttataattt
    16081 attagagact aattcaacta ttaaaataat aatcttgact ggatacgacc tcccagttta
    16141 taaacatgag gctaaaaaaa taggtatcta tggattccta aataagaata ttagccctga
    16201 tagtttaatt gattcattat taaaagtcta tcagggggga acttgttttc catctgaaaa
    16261 tactgaagta attattgaag atttaactac tatggagaaa agaattttac agcttatctg
    16321 tagtggtaaa aaaagaaaaa taattgctga tgaattgtat ataagtgaaa gaacattatc
    16381 aaatcattta caacacatat atgacaagct agatgtttca tcatcagttg aggctattac
    16441 aaaagctatt aaaatgggtt atatttctcc agtatattaa aaaaagtgag tgtctcaaaa
    16501 taaatcttct aactcataaa gcactctcct ttgtattaaa tcaaatatat tttcatcatt
    16561 taaacaatta agaagaggct tctctctatt ttgagacaac tccattttaa tacactattt
    16621 atacataaac atattttaaa caactaaaaa gcaactaata tcttaataaa tatctcaata
    16681 catatcttca taacacatat caccataatt acaagcagat aaagaactct cctcatttaa
    16741 atacgactca aattcatacc caaacagaat tgttggttct atatatattt ccatatctgt
    16801 atatctccat cttcttacct ttgcctctat aaccttgtaa aaatcttcta aactataccc
    16861 ttcttttaat cttttatcta taagtgcctt agttatactc aaatcagctt taaaattttt
    16921 tcctgattca ttatttaatt ttcttataat aatttcatgt atgctttctg gatttttgta
    16981 agtagaatct tcagtcaaat cttcatccga attttcaaag gtatttttat ttaaattctt
    17041 tttatttaaa ttatttttta ataattcttt tttctttgtc tcattttctg tttcataccc
    17101 agtatgaatt atcaaatcat aatctttgtc tatactctct tgatttatac ggctgtatat
    17161 gttggtatta ctgttcttaa acaactcatc tctatgttta tatttcattg ttttttggtt
    17221 attgttaata gttgcatcaa tgtatttctc tatatttttg aaaatatcac cattctttgt
    17281 tacaatttct gcattactac tttcagaaca aacataacta tatacagaac aacaatttcc
    17341 ctttactccc ctacttatta atctcaatat acctaaatct ataaattcat ttacaagtct
    17401 acttattgta gatatagata catcaaggtc agatgcagct ttccttactg tcatcataaa
    17461 ttgtcctctt ggcagagttc cttttaatct ttgtatattt tcttttctca ttacatagtg
    17521 attaaacctt attctattta catctctttt ttcattaaaa tataatactg ctgaatttaa
    17581 ttgataaaaa ctattactca tattcccact cctccaattt aaatagataa tttgttgtaa
    17641 agtttttaga tttttaaata acttattaaa tgattatttt tattaaaaag tattctttga
    17701 tattttcatt ttaaagtttt aagtataata agttaatagt gtagatttaa cttttttatt
    17761 taaacaataa acttaatatt atttttaat
//
LOCUS       DAEPXW010000082        17153 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.083, whole genome shotgun sequence.
ACCESSION   DAEPXW010000082 DAEPXW010000000
VERSION     DAEPXW010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17153
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.083"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(67..591)
                     /locus_tag="KRM55_002728"
     CDS             complement(67..591)
                     /locus_tag="KRM55_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1594949.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(656..1408)
                     /locus_tag="KRM55_002729"
     CDS             complement(656..1408)
                     /locus_tag="KRM55_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH1594950.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKLWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1439..2737)
                     /locus_tag="KRM55_002730"
     CDS             complement(1439..2737)
                     /locus_tag="KRM55_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBH1594951.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2754..5018)
                     /locus_tag="KRM55_002731"
     CDS             complement(2754..5018)
                     /locus_tag="KRM55_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBH1594952.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5273..6091)
                     /locus_tag="KRM55_002732"
     CDS             complement(5273..6091)
                     /locus_tag="KRM55_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH1594953.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6084..6782)
                     /gene="cbiQ"
                     /locus_tag="KRM55_002733"
     CDS             complement(6084..6782)
                     /gene="cbiQ"
                     /locus_tag="KRM55_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBH1594954.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6785..7069)
                     /locus_tag="KRM55_002734"
     CDS             complement(6785..7069)
                     /locus_tag="KRM55_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1594955.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7059..7811)
                     /locus_tag="KRM55_002735"
     CDS             complement(7059..7811)
                     /locus_tag="KRM55_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBH1594956.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(7993..8185)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8317..10089)
                     /locus_tag="KRM55_002736"
     CDS             complement(8317..10089)
                     /locus_tag="KRM55_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBH1594957.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10103..11032)
                     /locus_tag="KRM55_002737"
     CDS             complement(10103..11032)
                     /locus_tag="KRM55_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1594958.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11260..11448
                     /locus_tag="KRM55_002738"
     CDS             11260..11448
                     /locus_tag="KRM55_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1594959.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            11441..12142
                     /locus_tag="KRM55_002739"
     CDS             11441..12142
                     /locus_tag="KRM55_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594960.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12144..13067
                     /locus_tag="KRM55_002740"
     CDS             12144..13067
                     /locus_tag="KRM55_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1594961.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13224..14147
                     /locus_tag="KRM55_002741"
     CDS             13224..14147
                     /locus_tag="KRM55_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594962.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14140..14877
                     /locus_tag="KRM55_002742"
     CDS             14140..14877
                     /locus_tag="KRM55_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1594963.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            14888..15661
                     /locus_tag="KRM55_002743"
     CDS             14888..15661
                     /locus_tag="KRM55_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1594964.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(16202..16810)
                     /locus_tag="KRM55_002744"
     CDS             complement(16202..16810)
                     /locus_tag="KRM55_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBH1594965.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(16988..17104)
                     /gene="rrf"
                     /locus_tag="KRM55_002745"
     rRNA            complement(16988..17104)
                     /gene="rrf"
                     /locus_tag="KRM55_002745"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         5505 a         2979 c         2178 g         6491 t
ORIGIN      
        1 cctcattttt aagtaatata tatttttaat ttttatttat aactaaatct agtttttata
       61 taaattttag tttttttcta catctgagta atctattcca aaagtttcta cagtaacaga
      121 tttcataatt tgtggagttt gtggcttgtc agctgaatct gttctaactg atgctatttc
      181 atcaactgta tccatacctt ctatcactct accaaaacct gcatactgac catctaagtg
      241 tggtgagttt ttatgcatta tgaaaaattg agaaccagct gaattaggtg ccatagttct
      301 agccattgat atgactcctc tttcatgttt taaattgtta gtaaatccat taccactaaa
      361 ttcacctttt attgagtgac ctggaccacc cattcctgta ccatttgggc atcctccttg
      421 tatcataaat cctggtatta ctctatgaaa tattattcca ttgtaatatc cttcatttac
      481 taatgataca aagtttttaa ctgtatttgg agctatattt ggatataact caattttgat
      541 ttcttttcca ttttccattt ctatagttac tataggattt ttattttcca taatttatta
      601 ccttcctttt cattagttaa attacataat tacatttatt atattatact ctaaattaaa
      661 gtctatcaag tatatttttt cctatttcat atccttcttg ataaatagtt ttacaaaact
      721 catcatcaaa gttaagcgtg tctttaggag caaattgagt attaggtcta actactatta
      781 ttttatcttc atcatatact tttttaatat cttctggcaa ctcataatta tattttgtgg
      841 atattaaaat aattttatcc acattatccc caattaatgg ttcaattaat gcactcctaa
      901 ttaaacctcc atctaatttg aaaccatcat aaattccttc ttgcacatct ttcacaaatt
      961 gttctttaaa tccaagagtt gcgtttggat ttgatggtaa caacccactg tatgaaatgc
     1021 tgataatggc ttcattacga ggcatttttg atacgtcaac aatcttttct gatactactt
     1081 tattatcaac ttcaacataa ttaacataaa agttcatttc ttctatatta ctatcatcta
     1141 gttcccttag gttgtctata gcaggagaat tatccacagt attatttact atttttacat
     1201 ttccattctg gatatctttt atatttgtcc acagtttctc caagttatca acattccctg
     1261 tgtacaaata atatccattt attgctccta ttgatgtccc tgaaatcgaa taaaatttat
     1321 ttattcctcc atcatacaag gctttaacta ctcctgcttg ataagcccct tttgctcctc
     1381 caccttctaa acataatcct aatttcatag tctcatctcc aaattgttta tcttatattt
     1441 atatttcaaa aaacttacta aatgttttat atatactata gtggtcctca acatttccta
     1501 attctcttat agaatgcatt gctaaaattg gacttcccac atccacagat ggtatatcta
     1561 tatgagtaga agatattgga cctatagtac ttcctcctct ttcatctgac ctattaacaa
     1621 attcttgata ctcaacatta gcttctctac atatattttt ataaatagct atagaatatc
     1681 catcactagt atatgcctga ctagcattta tctttataac cggacctttt cccattattg
     1741 gtttattagt tgggtcatgc ttttctggaa tgtttggatg aatagcatga gctaaatctg
     1801 atgatatcat aaaagatgaa taaatagact caaagaatcc ctctctatcc ttacccattg
     1861 atatgcaaat tctctccaat atatttaaca acatgtttga atctgcacct tgtttagtag
     1921 agctaccaac ttcttcattg tcaaatacag ccattacatt tacaccatgt tgacctttag
     1981 tattaacaag agcattcaaa ctagcatgta ccattgcaag attatcttgt ctcccaatag
     2041 atataaattc atcattagcc cctattaaac ttcctttttc aaattcatat aaaaataaat
     2101 caaaatctat aatatcttcc atatttacat ctaagttaga tgctatttgc tttataagaa
     2161 aattatcttt ttctaatgta tcatttaaca tcccaactaa aggtaacata tctttttgct
     2221 tattatatga gtgaccatca tttatacttc tatttaaatg tattgctaga tttggtatta
     2281 tacaaattgg ctttttaaag tctataagcc tttcatttgg ttttaatata ctatcacctt
     2341 ttaaaactac tctaccagct atcccaagag gtctatctaa ccatgtactt aatattgctc
     2401 ctccatagca ttctgtattt aacttcaaat aagatttttc agcttctatt tctgcatttg
     2461 gtttaatact aaatgtagga gaatctgaat gagagcctat tattctaaat ccatctcttt
     2521 ctataccttc tgaatttact acaaaagcta ctatagctga taaattctta gtaacataat
     2581 actttccacc aactcttaga ttccatcttt gattcaaaac taattcttca aatccatttt
     2641 tatctaagat ttccttagta ctctcgactg catgaaaaga cgacggacta tcatatatga
     2701 agtctattaa gtttttagca aagtttatac tatccattcc tcatttacct ccattataaa
     2761 atatttagtg ttgtatattc tttatttatt tttttaattc cctgttggtc aaaagctata
     2821 gtaacatctg taccaattat agaaaccact gtcccaaccc caaatttagg atgatgtacc
     2881 ttagaaccaa gttttatatc atctggatta gtttctttat tagaatcttt tattgtagca
     2941 ttaactttat ctgcaacttt agatttgctt atagtactca tatacttttt agtatattta
     3001 tctaacatat tataacttgc tttagaatag cttagttctt tttttacttt gtacaatctt
     3061 tctatacatt cttctggcag ttcttccata aatcttgaag ctattgcaac atttgtttta
     3121 ccatataatg ttctcttctc tgtcaatgac atatatagct cttctttagc tctagttata
     3181 ccaacataac aaagtcttct ctcttcttct atttgtgaat cactcataga ttttatagct
     3241 cttgatatag gaaataaccc ttcttccata cctgttaaaa acacaacagg gaactctaaa
     3301 cctttagatg tatgaattgt cataagcgaa accctatcat tgtcttcttc atcatttgat
     3361 tcagatgtaa gtgctatact tgttaggaat gtctctaagt ctttattttc ataagtatca
     3421 tcattactac tttcaaactc caaagctata gaaataaatt ctctcaaatt atcaattctg
     3481 tcttgagctt cttcaccttt gcctgttaaa tctttttcat ttttatttct tatctctaca
     3541 agctcgtcca tatatcctgt agtatccaag actttttcta taagtttgct aacaggataa
     3601 acttctttta tagttctaag agtccctata atatcaacaa atccacttat acttgccctt
     3661 gccttagtag atatatctga atttgtttct atatcaatta atactgagta tatactttcc
     3721 tgttttaagt tagctctatc ttcaattttt tctatagttc taagccctat acctcttcta
     3781 ggaacattta taatcctttt tatagatata tcatcttgtg gattttgaat aactcttaaa
     3841 tacgccaaca aatcctttat ttcttttctc tcatagaatt ttgtaccacc atatatattg
     3901 tatggaattt gacttctatt taaagcgtcc tctacaggtc ttgcctgtgc atttgctcta
     3961 taaagtactg caaaatcctt ataaggtcta ttttcttttc tagctatttg tgcaattgaa
     4021 tcagcaatga aatcagcctc ttctatttcg ctaccagtta attgtatctt tataagttct
     4081 ccttcttttt tttcactcca aagctttttt ctttttcttt ctatattatt agatatgact
     4141 ttattagctg catctaatat cacttgtgta gacctataat tttgttctaa ctttacaaca
     4201 tgtacattgt cataatcttt ctcaaattca agtatgtttc ttatatctgc acctctccat
     4261 ccataaatac tttggtcatc atctccaaca acacaaatat tttgatgttc tcttgctaat
     4321 aattttatca attcatattg agctttactt gtatcttggt actcatctac cattatgtat
     4381 ctaaatctac ttctgtaata tgctaacact tcatcattag ccttgaaaag ttctacagtt
     4441 ttaagtatta aatcatcaaa gtcaagtgca ctatttcttt ttaaacggtc ttgatatagc
     4501 gcataaatat ctgcaatctt aaccattcta ttatctgcca tattgatatc tttaaactgc
     4561 tttggagtat aaagtttgtc ttttgctcct gaaattgcac ttataactgc ttttggttca
     4621 aacactttat cacttaaatt taattctttt agacagtctt taaccaatgt aacttggtct
     4681 gctgaatcat aaattacaaa acttctattg taaccaatct tatttatatc ttttcttagt
     4741 atacgaacac agcaagaatg gaatgtactt atccacatat ccttagtttc aggacctata
     4801 ttttgttcaa ctctctctct catttcattt gcagctttgt ttgtaaatgt tatagctaat
     4861 atatttggtg cttgtacacc tttatcttct ataagatatg ctattcttgt tgttaatacc
     4921 ttagttttac ctgaaccagc accagccagt ataagtactg gaccttcagt cttttctact
     4981 gcttctcttt gagcaggatt taatgtatct aaattcatat ttctcctcct gttaacagcc
     5041 ataaatatat tttaatctaa aatatgaatt acttcaaatt ataattatgt attatattaa
     5101 tagattattt ccaatatatt acaattaaat aacatttttc catataattt atttcattgt
     5161 ttaataaaaa aaataacctt atgatttggg gaatcataag gcacctttaa ggggtctagg
     5221 ttaagggtta ttatatataa atctattttt ttaaaatagg tttagggctt aattatttat
     5281 ttgtattaag ttctctttcc ttccaatact tatacaaatc ttcttctttc ttaaataagg
     5341 gtaaattcat atttctatgt acttttacta accatgggga ttctaggcca gcttgtataa
     5401 tattattttc atttataaac acattttctg cttttccttc atcaatcaaa atccccttat
     5461 ccaatacata tatgtaatca catatttcat acattaaatt catatcatga ctggatatta
     5521 ctatttttat attattttta tttaatccct ttattatatc tacaatagac ctagtactta
     5581 ctgggtctaa accagctgta ggttcatcaa gtaatacaat ttcattttcc attgctataa
     5641 ctgatgctat tgccactctt tttttctgtc catagctaag aaaatgtact ggcctgtcta
     5701 taaaatctat tccattaaca gctactagag ctttgtttat tctctcttta attgtttttt
     5761 catccatacc aatgtttctc attgcaaagg ctatatcatc atatactttt gaataaaaaa
     5821 tttgtttttc tgggtcttgg aagacaatac ctacattttt tctaaggttg tataaacttc
     5881 tcttatcata ttttaacttt tcttctttaa aaagaatttc tccagatgta ggctttaata
     5941 tacccattaa attcataaat aatgttgatt ttcctgaacc atttgaacct attataccta
     6001 taacatttcc ctttgaaaaa tccatattaa tgtttaatag tgcattggta tttttttcat
     6061 attgatacgt taaattattt attttaaaca tcattatccc ctactatgtg aaatttacca
     6121 tcatacaatt ttatgtctaa tgatatacac atatcatcat accttgtcat aagtcttttg
     6181 tacagcatac ttccaagaat acctaaggat ttatatgaag tttttaaatt tatatatcca
     6241 aatcttagct cttgtgactt gtatatttct gaaaattctt ctaaaaatat gaatataaac
     6301 ctatatatta acattgataa ctcgacaaaa gtgtcaggta aatgaagttt tttaaaaaag
     6361 aatattaatt gattaaaagg tgttgtaagt atacaaaaat acacacaagt caaacaagac
     6421 atcgctctaa ataacacatg aatagacatg tcaatagacg cctttgatat tcctacatta
     6481 aaactaaaaa attcaaaact atataataaa tctgctttat taaaagatat atttacaaga
     6541 gttattccta tactaagaaa taaaaagtac attggtattc taagtaattt taaataattt
     6601 tttaaatcta ttccagccac acaaacaacc aaaatactca ttaaaatcat aattccactt
     6661 aaaataaata tattttgtat taccatagaa gcaatcagaa aaattactcc tatggctact
     6721 tttttgtttg gatttacttt actcaatcta tttgtatatg catatttatc aattataagc
     6781 atgattaact tctctttcct ttttgaagac ctaatatgta tcctattaca ccagccccta
     6841 aagctgcttg tgcagagaat aataaacttt ctatttctcc acttggtggt tcatatggac
     6901 tgctaaacca tggtttgtaa tttggattta tcttagtaat ttcactttca gcttgaccat
     6961 ctgctcctcc atattcagca cctgagttga caagtaatgg gaatataata agagctacta
     7021 ctaataaaag taataatatg ttagtttttg tttttgtttt agcactcatt agctttaact
     7081 cctttatcat tattttctag tatgcttttt tctccgtttt ctgtaattaa attatataca
     7141 attacagtaa gtataccttc tgctattgct attggtattt gagtcataaa gaaaattcct
     7201 aaaaatttaa ttgctgaagc cattacccca cctgatgggt ctgggaaagc cagtgctaat
     7261 tgtattgaag ttattgtata tgtggctaag tctcctattg ctgctgcaag aaatactgga
     7321 atagcattat ttccatcttt tttctttaaa gccttaaata ttaggaatga tacgattggc
     7381 cctattatcg ccattgaaaa agcattagct cctaaagtag ttattcctcc atgtgctaat
     7441 aacaatgctt ggaatattaa aactatagtt ccaagaacaa acattacgct tggtccaaac
     7501 attattgctc caagacctac accagtagga tgtgaacaac ttcctgttac tgaaggtatt
     7561 tttagtgctg ataatacaaa cacaaatgct ccacataaag ctaataatac tttcttttta
     7621 gggtcttgct ttactatttt acctattgat tttaatccga ataagaaaaa tggtataaat
     7681 ataactcccc atgctataga ccattttact ggtaagtaac cttccattat atgcattgca
     7741 tttgatgtaa ctggagttaa aatgattaac ataagtgcag ctataacccc taatttaata
     7801 ttctgtttca tcttagtatc cctctctccc tttctaataa ttaaaacata ataatacatg
     7861 tctgatttat ttaataaaat aaaaaagcct aactcgatgg ttaggcttct aattttccac
     7921 aatctaaata caaacacata aaacaaacat atctgtataa ttattataag aaactttctc
     7981 catccccgaa gaaattactt taatatttta ggcaggtctc ctgacttagc ttcatcctac
     8041 tcctcttcct tcccatgaga tataaaaaat atcatcatag tggctaacaa aagtttcgtc
     8101 tgcatcacag tagcgggggc tgtaaaggaa tttaaccttt ttccctatta atcttgctta
     8161 aagaacctat aatattatat atttaatttt taaattcttc ttaaattatt ttctatataa
     8221 atcattgtat accttttctg tgaaaatttc tacatttttt ataaatttta ttcattttta
     8281 tatttttatg tatataaatt cttttttgta agtttattaa tttctaatta tcttctttaa
     8341 atacattgaa actacatcag aaaatctagt tatatctctt gaatatataa aatcatttcc
     8401 atatattaat ctttcagctt caagttctga ttcttttcct gtaaatactc ctaatactaa
     8461 tatattttgc tttctagctt ttctcacttc attggctgta tctctcaaac caactatacc
     8521 cctataagcc ttttctcctc ttaatgttct ctcactactt tttcctatct ttacatcatt
     8581 tggtcttcca tcgctgagaa ctatcaggat tttattttct tcatctctat ttattagacc
     8641 actacatata gattttattg ccaaaccatc tctattatta ccagcacaaa aatattcaaa
     8701 tatattttca ctatttttta tactatcatc ataatcttta aatcttttta atattgtata
     8761 gtctaaaaaa ctagaaaatc ccatcactct atttggtatg ccaacttctg ttagagcatt
     8821 tgcaattatg taagcttgaa ttgccacatt tccctgattt ctactttgag agccacttgc
     8881 atccaataat atatcaataa cgtatttccc tttttcattt tctatatctt tataaaatat
     8941 tttattatta ttacttctac caactctcca agctctattt gctaatatag taccacaatc
     9001 agaatatact ctacttttag cattttcttc tattaaaatt cttgatagac tttcttttaa
     9061 tctctttatt tgctgcctat acattctagc atgttctcta aattttccta aattattttc
     9121 tttttgtctt gttacatatt ttagttgaaa tacattatta cactcacttc taagaactcc
     9181 atctgtaaag tgtattctac aaccttcatg aacatttcta caattttgtg tctcaatttt
     9241 tttaatttca cctttactca aataagtttt tccataataa tgttctattt ttgaatatat
     9301 cttatttgca gtgtcttcat caacatatat aactcggtct gctgaattgc tacatttaga
     9361 atcatcaaaa tcccctacac cttctacaag catggatgaa gatattgaat ctatatcact
     9421 ttcaataata ttttcttctt catcactata aagttcttca tacatgaaat cagcaaatgt
     9481 atcaaaattt acttctacac tttctacatt attttcatca ataagactat tttcttctcc
     9541 atttaatatg tattcaaaat aagttaaata tataacatct aatgctttta aaatctccat
     9601 aatatcttga ttggtatcta tatttcttat atcattaact attcttctag tcatactatc
     9661 taatgctggg tgcttgtcca tactataaag tacaaatgtg tatttaattt tatccataat
     9721 attatcattg tgtattttgg taaaacgtga aacaatatct ttataagcat ttcttcttat
     9781 gtcttctatc cctggcctat ctttaatgac cttttcttca actattgtat ttaatataac
     9841 ttgaattaga cccagtataa tatctttgtt gtatcctttt cttattctat ttgtaagata
     9901 ttttttaact atatcccaat ctacatactt tcttctagca cctgcaatta ttgcaaaata
     9961 tagacctatt tcttttgaag agtaatcttt ttctgatata tctatacttt cattgtaatc
    10021 accagctatt gtccatgata agttattagc tctattttca aattcataat catcatatat
    10081 ccatttcata atctcaccta tattaaatat gacttattgg aaacacatct atactctccc
    10141 atttattagg tattctagtt ttaattacat ctccaaccat ttctttctca tatacatcaa
    10201 aagtctttcc tgtaagtccc atattaattg caagagttgg ttttaatcct cttcttatag
    10261 tcttaagaga tgccataaga ccacgtaaat caatagcttt actagatatc tctccatttt
    10321 gagacttcaa ttgtaaatct aaaaatattc ctgcaaagtg tattagtttt tcttcatcag
    10381 catctgaaaa ttcatttttt aaaatcatca ttaacttatc ttcttctata ggaggaatat
    10441 ctattaccat aaatctagat accagtgctt cattaagttc ttttgttcct gcatattcat
    10501 aattcatagt cccaataaat cttgttgctg gatgtagatt gactctctca tacccaggta
    10561 catcaattat tcttctatag tctaaagctg aatgtaccac aactatagca tcattttttg
    10621 ccatattaat ttcatcaaac accccaaaac ctccattaat agcacactca taaactgagc
    10681 ctcttctaag tttaacttca ttgtctataa atgtatctgt acctataagt gttgaactgt
    10741 ctgtatttat atgaaatgat gtattccact gaggtctatt aaatatttcc cctagattat
    10801 cagcaagtaa gttttttcct gttgcctttg gtcccgataa taatatattt tcttcttcta
    10861 aaatagctgc tatacacata gacaagatat ctttaccata aaaataagtt ttagactttg
    10921 ttactctgta ttctaaatct ttttctaatc cataataatt tctaaaatac agtacatctt
    10981 caataagttt ttcatctacc ccttgcaccc ttagattatc tattatatcc atatttttac
    11041 cccttttata taaatagtat ttgtttcatt tcttatcacc attttagcat aaaaggatat
    11101 aagctaaaat tgatttttta atctccccat tttaagtaaa accatgcacc attttatcac
    11161 tacaaaatta agagtactac ttactgatat ttcttgattt tgttcgtcta tacgtatata
    11221 atatatgctg ataaattatg aggaaaggat gattgaaata tggaatatat gtcttgccca
    11281 gaagtagcaa aaaaatgggg tatttctgaa agaagagtac aaaaactatg tgaagaaagt
    11341 cgcataccag gagtttcaaa actcgggtat atgtggctga taccaaagaa cgcagaaaag
    11401 cctgttgatg gtagaacaaa aagaagaaag gaagtacaat atgaatagcg ttttgattat
    11461 agatgatgac aaagaacttt gtgctcttat gaaaaaatgt gttgagcaag aaaatttatc
    11521 tgctattact gcacattgtg gtgcagaagg tctacatttg gtcgataaaa atagacacac
    11581 actctctctt gtaattttgg acataatgat gccagatata gacggttttc aagttctgaa
    11641 aaaaattaga gaaacaagta atattccagt aattatgctt actgctaaaa atgacgagga
    11701 tgataaagtt tccggactac gtttaggtgc tgacgattac ctaacaaaac cgttcagcat
    11761 aaacgaactt atggctcgtg tcaattctct tattcgtcgg tatactatgt taaaccctgc
    11821 ttttataaca gacacagatt gcataataat aaatggcatg attattgaca agacaaaccg
    11881 aattgtttct gtcaataata ttcctgttca acttacaagc aaagaatttg atttacttgc
    11941 ttttctggct tctaataagg gacgggtgtt taccaaaaaa cagatttata cacaagtatg
    12001 ggaagaagaa tatgcttttg acgatagtaa catcatgtct ttcatcagta aattgagaaa
    12061 aaagattgaa ccagacccca accatccatt ttatattttg acagttcgtg gtgtcggtta
    12121 tcgttttaat aaggaggctt aacatgaata caagtgtcta tctgcttttg atattggttc
    12181 ttagcctgat tattatagcg taccttgttt ctgtcctact acgtgtccga atacaactta
    12241 cacttataaa agatgcttta gaggatataa aaaatggaaa ccttaatcga cgtattttaa
    12301 cagatgaaaa cgacattaca aaacaaattt gctatgatat taacgaaata gcaatcaata
    12361 gccaatttca acttattcag caaaaacaat cagaacaagc ctacaaacag ctaatgacaa
    12421 gtctctccca tgatgtaaaa actccacttg cttctttggt cggttatttg gaagcagtag
    12481 aaagtaaaat tgttgtagga gaggaaaaag acgagtatat ccatgttgcg tctaataagg
    12541 ctcattactt aaagaatttt gtagaaaatc tatttgaatg ggtaaaattg gattctaagg
    12601 aacaagtttt tcattttgat atttttgact tgaatgaatt atcccgtaat attatatctg
    12661 attggatacc tgttttagaa agcagtcatt ttgaatatga atttgatata ccagaaatag
    12721 agtacttctt acgtatagac gcaaatgcat atacccgtat cattaataac ctattacaaa
    12781 atattattac ccatagtagt ggcaacaaaa tgacattgag aatttttgaa aacaaagagc
    12841 aagctcaaat tataataaca gataatggga aaggtatatc ttcagacaat ctcccacata
    12901 tttttgaaag gttgtaccaa tgcgaccatt cacgagcttc aaagggaaat ggtttaggct
    12961 tggcgattgc aaaggaactt attaacgctc ataagggaaa tattaccgcc aacagcactc
    13021 ccggtatggg aacagaattt acaatattgc ttcctaaagc cctgtaaaag tacgaggctt
    13081 tcttactcta aaacaagata aaagcaagat tatggcaagg ttttggcaag gttcatgttt
    13141 tataattcta attgtagttg attttgacgt tgtatcaact atcttttgta gaaacaaatt
    13201 tattaaaagt gaggaaatta tatatgaatg attttgtgat tgaaacaaag caacttacaa
    13261 aaatttatgg gaatcaaaca gtagttgaca aagtcaatct ccatgtaaaa aaaggccgaa
    13321 tatatggtct gttaggacgc aacggagctg ggaaaaccac aattatgaaa atgattttag
    13381 gattgacttc aatcacgtat ggcgaggtag atgtatttgg agagaatatt aagggacgtg
    13441 aaaaacaagt atatccccgt atcggtgcaa ttatcgaaac gccaggattt tatcctaatc
    13501 tgacaggaac ggagaacttg gagatttttg caaaactgcg tggtacagcc gcccctaatt
    13561 ctgtaaaaag agcattggaa attgtaggct taccttataa aaataaaaag ctgtttagta
    13621 aatattcact tggcatgaaa cagcgacttg gtattgccaa cgctatcctg catgacccag
    13681 aactgttagt tttagatgag ccaaccaatg gtcttgaccc tattggtatt gcggagatga
    13741 gaaagtttat tagggacttg agcgttgagc atggaaagac aattcttatt tccagtcata
    13801 ttctttcaga aatctcattg ttggctgatg atattggaat tatcgaccac ggtgttcttt
    13861 tggaagaaag tagtatgagt gaactagaaa agaaaaacag taaatatatc ctgctacaag
    13921 tttcagatat tccgaagaca tcacttattt tagagcgtca atttaacacg aaggattatt
    13981 ccgttcaaga tgactacacg ttacaccttt ataacactaa tctggatatg ggtgaaatca
    14041 ataaagcact tgtaatgcag aatgtaactg ttattagttc tcaactttgt aatgatactt
    14101 tagaggacta ctttaaaaaa atcacaggag gagagggcat tgcttaaact tattcaaaca
    14161 gaatttctta aactgcgtcg taggaaactt atttggctga tgttgttgtc tgctctcatt
    14221 atgccgtttt tcgcactact atacttcaat tattttggta aaacaggtgt tgagccaata
    14281 aagttttata aatggtctgc atttggttat acactttgga ttattttgcc tgttgttttg
    14341 ggtatatttt gcaccatgct tatacacgaa gaaaaccagt atgatatgct caaacagctt
    14401 tggattgtac ctattagtaa aatgggatac ttttttagta aatttttcgt tgttttgatt
    14461 tactctattt gttttatgct gattacagcc gttgcttctg tgttatttag tgtactttct
    14521 ggatatgtcg tatttagctg ggcaagcatt ttatatttgt tgaaaaaatg tttagaaatt
    14581 ggtgtaatca ctgcttttgt aatgttgccg attttggcaa tcgctacatc tcaaaaagga
    14641 tacattctcc caatttgtat cacattggta tatgcctttt ccggttttgt tataatgaca
    14701 ataaatatgt atttacaccc attatccagt atgggagtta ttatcatgag aaataaagac
    14761 attccaggtc ttatattttc acaggaaatt aatgtcccat tagcatttct ttgtatttgt
    14821 atttggagta ttgtatcagt attgtttgca aatattgcac taggaagaag aaagtgaggt
    14881 gtagataatg tggaaattac tttgggctga atgtcaaaaa attcgtcgtt caaaaattgt
    14941 ttggattaca gtttttgcat ccattatgat agcagtcata gtttttgcag gggggcagga
    15001 tgtatataat gacccagatt tacattatgg cttaaagagc gtttatgacg gttcacggta
    15061 tatagacaat gcaggttggt atatggacgc agtacaacct tggtcaactt tttttgttct
    15121 tcctgctgtc attgccctat taggaagcta tattatttgt cgtgaagaag aggaggacac
    15181 tattaaatcc ctgcgtctta ttcccataaa tgaaacaaat ttaaccatag caaaaatgat
    15241 tattactttt atattcagta tacttcttta tttgttactc tttactataa catttttgac
    15301 tgaatccgtt ttacattttt ccgatttatc gacaaaattg gttttaagtt gcatgaaaga
    15361 gtattttctt gatggcatag gtgtattctt tgcaatttct cccattattg ccttggtatc
    15421 gcgcatgaaa aaaggatatt ggcttgcatt agtattcaca gaagtttatt ctattgctgg
    15481 actatttgcg ggtatgtcaa atgtcttaca aacctttttt cctattgcgg caatatttaa
    15541 tatttctgga tactatataa ctactggaga aaaaattatg gggagtatca taagtttatt
    15601 actttgtgcc tgcctttctg catttatact taaagggcta aaacacaatg aaaaaaattg
    15661 aaataggtat atcaaaatga aaaagataaa aaaactgatt attctaattg tattcttgtt
    15721 tctttttggc atgttacact gttatactga atggaaattc aacaataacc cacctaaagg
    15781 ggtaatagaa agaataaatg agtggactga taagattgga ctggattagt aacttatgtt
    15841 aattatagtg aatgtaatat tagcaagtta ttgtttcgta ttttaatact ataactttaa
    15901 atatttggtt ttaatcttcc aaacgaatat aaaaaaactg tcacagaggc aacatatttt
    15961 tgaatattta taaagtggta gttttgattt tcaaagctac cgccttttct tctatataag
    16021 caaacttatc ctcaacaaag tgtaaaacat ggtacatttt aagaaaaaag taccacagac
    16081 acaagcaata aaagaaacgc cgagaaccta caaaaacgta gtgcttatgc agatttacga
    16141 cgccttctat tttctcaacc gtcttaatga ccttgtacaa aagaaatttt tctaatattt
    16201 tttataatct tatcttgtga tgttttttat gtataaatga cttaataaca aatccaataa
    16261 aaattatgga tattggtata attagaacga ggaatttata atcattataa tgtgacatta
    16321 ttcttaccca actctcagaa aaaatatatc ctatactgat taatgaagta ttccatatgg
    16381 ttattcccac gatagatgat attacaaaag ttataatatt ttgccctgct atacctgcta
    16441 taaaagatat gtatgttcta cataaaggga ttaatctaca tacacaaaca gaaatagaag
    16501 agtatttatt aaaataatct tgagatgcaa atattccttt ctttgccttt ggacatatct
    16561 ctattatttt atttatgata gatttacctc cccaatttcc cactgtataa caaaatatcg
    16621 aaccaagtat acctgcaatt atacttaaaa ttaaaattgt cagaaatcca aaatgatttc
    16681 ttgcagcaat tgctccacat aaaggtaaaa caacttcgct aggtaatgga aaacaagcat
    16741 actcaatcat aattaataca aatacagaga ttaatccata ttgtaaaata aaactattga
    16801 ttacagacac ttacttatct atctcctttc ttatttaaag gttttaaggg tacatgttct
    16861 aaggattctc accctatatt taaagaatca atctctttaa actattatat gtatttacac
    16921 aaagcattta taacatactt taaaaatagt accttaaaat aagaaactta ataaataaaa
    16981 aaagattacg tggctacgtc ctactctccc aggcagtttc ccaccaagta ccatcagcgc
    17041 tagagagctt aacttctgtg ttcggaatgg gaacaggtgt atcctctctg ctattgtaac
    17101 cacataatct ttatgcttaa tatttccatt aagtttttaa taagtttata gaa
//
LOCUS       DAEPXW010000083        16595 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.084, whole genome shotgun sequence.
ACCESSION   DAEPXW010000083 DAEPXW010000000
VERSION     DAEPXW010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16595
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.084"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(416..1396)
                     /locus_tag="KRM55_002746"
     CDS             complement(416..1396)
                     /locus_tag="KRM55_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594966.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(1560..2432)
                     /locus_tag="KRM55_002747"
     CDS             complement(1560..2432)
                     /locus_tag="KRM55_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1594967.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITFKYEK"
     gene            complement(2596..3147)
                     /locus_tag="KRM55_002748"
     CDS             complement(2596..3147)
                     /locus_tag="KRM55_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1594968.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(3167..4069)
                     /locus_tag="KRM55_002749"
     CDS             complement(3167..4069)
                     /locus_tag="KRM55_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH1594969.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(4084..6456)
                     /locus_tag="KRM55_002750"
     CDS             complement(4084..6456)
                     /locus_tag="KRM55_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBH1594970.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(6677..7361)
                     /locus_tag="KRM55_002751"
                     /pseudo
     CDS             complement(6677..7361)
                     /locus_tag="KRM55_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7602..8981)
                     /locus_tag="KRM55_002752"
     CDS             complement(7602..8981)
                     /locus_tag="KRM55_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1594971.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNEGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEVCLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(8975..9688)
                     /gene="rgbR"
                     /locus_tag="KRM55_002753"
     CDS             complement(8975..9688)
                     /gene="rgbR"
                     /locus_tag="KRM55_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBH1594972.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNAAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(9938..10498)
                     /locus_tag="KRM55_002754"
     CDS             complement(9938..10498)
                     /locus_tag="KRM55_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBH1594973.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKTNKVKSVLFMNMFVFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYVVQLYRRLMYYLRLKKFK"
     gene            complement(10594..11397)
                     /gene="zupT"
                     /locus_tag="KRM55_002755"
     CDS             complement(10594..11397)
                     /gene="zupT"
                     /locus_tag="KRM55_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBH1594974.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(11548..12711)
                     /locus_tag="KRM55_002756"
     CDS             complement(11548..12711)
                     /locus_tag="KRM55_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1594975.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(12771..13958)
                     /locus_tag="KRM55_002757"
     CDS             complement(12771..13958)
                     /locus_tag="KRM55_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594976.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTYEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(14321..16021)
                     /locus_tag="KRM55_002758"
     CDS             complement(14321..16021)
                     /locus_tag="KRM55_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1594977.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(16276..16551)
                     /locus_tag="KRM55_002759"
     CDS             complement(16276..16551)
                     /locus_tag="KRM55_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1594978.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
BASE COUNT         5463 a         2953 c         1636 g         6543 t
ORIGIN      
        1 catattctaa tataataaaa caaattaaat aaaaaaaaac cataaatttt aaatttatgg
       61 attaattctt gtaatgataa ctctatttga ggatgtgagg gagggttatc attacaatag
      121 ggtattatat tatggttttt aagctagtct ttctacacct catatgatac atatgctata
      181 tgaattttat atgattttta cataaatatt ttatgaaatt taaatttttt agtcattttg
      241 aaatttgtaa aaagttctct aaaaatccac agcatcataa acagccaaaa tttaagtaaa
      301 acatcataaa aaaatttgtc caataatttt aacaagtaat ctcacctcat cataattatt
      361 gacacaaact taaataaaca atctataaat cttctataaa tcttaaactt tccccctatt
      421 gatacacaat ttctagtttg tcaattttat tttgcatttc taagaaaatt tcttcaacag
      481 aattgttaaa tatattgcct aaatagattc ttttatcttt ttgaaatgaa taagatttta
      541 cactaccatc agaagaaata tataaatgac tccactctgc tccatatttt gaaaacctct
      601 cttttgtatc tttaaacctc atatcttcta tttttattgc tttttctctg tctcctctta
      661 ctacagtgtg accccttttt attaaactgg ttatttttat atcttctttt aatttaatac
      721 gtgtatcatc attttttgaa tatactttcc atatcacttt atgacgataa ttatctaatt
      781 cctttattaa gcttctatca atagtaaaac tatctttagt taccacaatt aaatcaaaat
      841 ggtctaacat atattgaaat atttctctca tacttttatt ttttaaaata tcctcaccaa
      901 taacctctat aaatctacag cctttctcat acatgcagtt caataaactt gtgatttcag
      961 aaaaataatc atttgtatta ttatctccat ctatttctat agtaaagtac aaaggagtaa
     1021 tgtatgattt atttcctgtt atctcaaata cacttgatag tgtctgtata tcatcttcaa
     1081 acgttaagta cacattctca taaaacataa aaaattccat aactttttct ttcatattat
     1141 ggatatttct atatctattg gataatatat ttattatatc gtcagtagta tttttcccat
     1201 cacattcagc cagtataaca atttgcttcc aacttaagct atccacattt ccgatacttt
     1261 ttttatatcc atcttcttcg tcataaatag gaccaattat aatgttttct tttggccaca
     1321 gatgaaccct agttccatct tttaatttcg gatatttatt ttttacagac tcataaaatc
     1381 tacttgtatc acccatgatt ctttactacc ccccatagtt taaatattct atgctaaaaa
     1441 tagcacttta tttttattaa ttcaacaatt attcaaaatt ggtcattata tatgtttaaa
     1501 tggatttaac atcaacctta tttatatgtt attgatgttt atatatgtta tataaaatct
     1561 tatttctcat acttaaatgt aatcttaact atctctggtt tacaattaag cctaattaaa
     1621 acttttgagc ctcctaagcc tttatttaaa atcatagtgc tattatcttt ttcatatttt
     1681 ccccagtcat acttaggaaa gaactctcta tttggagata atacacctcc aacaaaaggt
     1741 attcttatta tacctccatg aacatgtcct gctaaaacca aatctgctcc ccattttgca
     1801 tatttttcaa agaaaaatgg tgtatgtgct aaaagaatgt tatattcatt ttcattaact
     1861 ttacctagat tgtcttctac aaaattgtca cttagttcta attttttgtt attagcaaat
     1921 aaatatggat agcattccaa tggtataatt aaaccatata aattaagatg gctattacct
     1981 ctatatattc ttacagattc attttccata tttattattt tctttgaata tagttcctta
     2041 aaataatcct tatatagatg tttatacttt tttattaaag atttttgttc atgatttcca
     2101 attatatgat atacttcata tttttcaacc aaattatcta ttaaatctaa tgcaacttga
     2161 aaatttttat tttctccatc tactaaatct cctgttataa atataacatc tgggtttaat
     2221 gattcaattt tatctatcaa taccttatta tttttatcaa acaccttatt atgtaaatca
     2281 ctcacttgaa ctattttaaa gttatcaaat tcctttggaa tttttttgtt gaaaatagta
     2341 tattctgtcg tttctatatg ctgagtttca tacttataca gaatatacaa taatattaat
     2401 actaatactg tcattgaaac ctttataatc atattctctt cctctttatt ctattttgtt
     2461 aatattatta taatgctttt atgttttttt taaaacaata acatcatcac atacatataa
     2521 atcttttcga cattataaaa ataagttatc cttttctaaa attttcattt attttagaaa
     2581 aggataacta taaaattatc tataaacctc tatattgtga aatatagttt ttcctttatt
     2641 taaattttta tatatatgct ctaaagttcc atcaaaccta atagaatgtc cagactctaa
     2701 aatataagtt ttcccatcca cattaaggtc aagtttacct tctattacga gtacatactc
     2761 ttctaaaaca tgactatgtg tagatgaaac atgagtacag ttttcctcaa gctcaattat
     2821 aaaaagttca aaccttcttt gagggctaaa agggtatatt ggatataact tcatgttccc
     2881 tttttgctca acaataggct ctacttcttc tttttttata acctcatagg tatttgtatt
     2941 ttcatttaat agtgtagtaa aatttatttt aaatccagat gaaattttcc ataaagtaga
     3001 tactgtcgga cttgattcac ctctctcaat ctgtccaagc attgctttac tgacacctgt
     3061 catctttgaa gctttgtcta aacttatgcc catttcttgt ctcaataacc ttaaattttc
     3121 tcccacatta ggaaatttat tatccatgtt aaaatcctcc tgatagctat ttgtattcta
     3181 tgatttttac tcctgtaagt tctactatct cttttaattt taacatatga ttgttacaaa
     3241 tttcatcaaa ttcatatata taatcttcaa gccctaatgc cttatattta tcgattccaa
     3301 atttatgata tggaagtaac tccatttttc ctcctggaac attttgtttg acaaataatg
     3361 cagtatttct tatattttct tcactatcat ttactccata aataattggc actcttataa
     3421 ccatagattt attcaacttt gaaagcctac atatattatc taatataatt ttattactta
     3481 ctcctgtata ttctttatga atattatcat ccatagattt tatatctaca aatatgtggt
     3541 ctattttctc aaatacatca tttaccttat tccaatcaaa atatccacaa gtttcaattg
     3601 caatatttat gcctttatca taaaaaatat caactaattc tcttaaaaaa tcaatctgaa
     3661 gtgtaggttc acctccagaa aaagttatcc ctccattaga ttcaaagaaa aatataaaat
     3721 ctttttcaac ttcctctact atttcttcaa cactcatttc ttcggtcatt atacaaatgg
     3781 catctttaag acataccttg atacactctc cacataaatc acatttatta tttatttgcg
     3841 ctctatcaaa tagtgaactt atattttgag gacaaacatc tatacatcta ttacaggata
     3901 cacatttatc tttcataaca cctaatttta ctatgttact ccaggaatct ggattagaac
     3961 accacttaca ttttaattta catccttcta aaaatatagt agtccttatt ccatctccat
     4021 catttactga aaaatgttgt acttttacaa ctctaccttt tttactcata atctacctca
     4081 taattaaaaa ttgctatgtg aatttctagc tattatagca tcttgcattt ctcttgataa
     4141 attaacaaat tgagtactat atccagcaac cctcactaat aaatctttat attcttctgg
     4201 attttcttga gcttttaata gagtatcatt tgatatcgta ttaaattgta catggaatcc
     4261 tcctaaagca aaatatgatt taatcataga tgttagattt ctaagtcctc tttcagtttc
     4321 caccaaatct tgattcagtc ttaaatttag aagtgttcca ccagtatgaa catcatgatt
     4381 tatttttgat gcagatttca ttgctgctag tggacttgtt gtatcagtac caacaaatgg
     4441 agaaactccc tctgtcaaag gttttgtcgc ttttcttcca caaggagttg cacctacgat
     4501 ttttccagtt ggtacatagt ttgatatacc cataaatgca ctattaaatt tagagccaaa
     4561 aatatccttg tattttctag tttcagtata ataaaaatca gaaacttcaa ttgctaatga
     4621 atctacataa tcattatcat ttccatactt aggaacatcc aacgcaagtt ttcttaattc
     4681 ttcataacct tcccaatcat tatttagtgc ttttgttaat tcttctagcg tagtcacctt
     4741 atcctcaaat actaattttt ttatagctgc caatgaattt gaaactacac ctaaccctat
     4801 accagttaat acaggaccta tattatattt tgctcctcct ttacttaaat caactccctt
     4861 atccaaacat ccatctacac aagtagataa aaatggtctt ggtaccattt ctttatgaat
     4921 ttgttgagca acagtagttc ctataacaga actttttaca agatatgcta attgctttaa
     4981 aaactcatcc ttaagttctt caaaagaagt aaattctgtg atattttttg tatctaaccc
     5041 cattttttct ccagttaatc tactcttacc ttcattcata gcatattcta aagctgctgc
     5101 aaaattgata tttacggctg aagtccactg tcctgttttt ctaaaatgag gaactacaca
     5161 accacagtta ctccaatctc tagcatcttc tgcatcatat ccatcttgta ataacatttg
     5221 tgcccctgca ctatcgctgt gtatagcagg gaaaccagtt ccttgtttta ccaatttagc
     5281 aactgccatt acgaaattgt ctggtgctcc ttgactcact ctaacactta atcctggctg
     5341 gtgagttttt acactttctg tagcctttaa acacatatat gagatatcat tcgttccatc
     5401 agtaccattt ctctttttac caccaacagt aagattttgg aattgattat atcctgcaaa
     5461 gtaatttgct gtatttgctg atatagtcca tacccattct gataacttaa tccaaagtgc
     5521 ttctatcaat tcttgagctt ctgattcagt tattttacct tctctagcat cattttcata
     5581 atatggatac atatattggt caaatctacc taaatttaat gccaatggat tttctgatag
     5641 aataccacct aattgaacaa accatacaaa ttgtattgct tcataaaaat tagttggagg
     5701 gtttgctggt acattcatac atatctctga aatttttata agttctaact ttctcttttc
     5761 atctgtttct tgcttactca tctcttttgc aagatttgaa tatctttgtg ccaatgtcat
     5821 aataccctgt gcaactatag aaacagattt gtaaaaatct atcttttcaa tattttctga
     5881 aactgatata tctaattctt taattttttt atctgcatct tccttaatcc ctttatatcc
     5941 ttttacaaac aatatatctt gataatctgg tgttacttca ccaactgcct gtctccactt
     6001 agaatcatta tctattattc ctgtatctac taatatctta gctgtatctt ctgggattct
     6061 tgctaagaaa acttcttcca aagattttcc cttccaatat ggaaatattt cttttcttat
     6121 aaattctatt tgttcttttg atattacata tgggtcttga gttcttttat caaaagtatc
     6181 catttctttg tctacccatt gccaagaaaa ctctggtgtc aatatccctg ttcttctaaa
     6241 ttttcctgct gtacctacta ttaattcatt ttcaaagatt tttataggaa gttctttaca
     6301 tgtctccaaa aaagctttag ctcttcttat acatatagct tctccctcag tttttttatg
     6361 tgattctgta aaaattctag ccctttcaca acatatcata ggtttagaat taatatattc
     6421 ttgtctaaat gcttctattc tattagtttg actcatttaa aatccccctt tggataatat
     6481 atactacatt tttgtatgtt ataacatact ttaattatat tatactgtcc tttagcataa
     6541 aatggaagca aaataactta ttttttttca tctaccttga acacctatat attaatactt
     6601 tttttgttaa atttataaaa tctaaaaaaa ttttctatga tatattttct atattgttat
     6661 agttatttct aatatactaa tgatttgaaa tatcaaattt gtatactaga cttagtttta
     6721 aaaccttagt tgattgttta actttgttaa cttcaacatg tatatccttc atataaggaa
     6781 gctctacaac acctactccc ttattaaagt cttcttcaac catagaaaaa atttctttct
     6841 cagttaagtt cgtattagtc aatgatttaa ataaattgta tataaattta atatatttat
     6901 cactctcaga taacttatca tcttctggat actctttagc acagagaata tctattgtta
     6961 cttttccttc tttatcgtct tcagacatag aatagaataa acttcgaata tttttttcag
     7021 gtggtttttc agcaccattt atagatacta caaagctacc atctgatttt gagttagtaa
     7081 tactataacc actgtctatt atagctttcg aaaatctttg agataaatct ttttttactt
     7141 cttctctacc tttcgcatca ttaatctttt gtgagtaatt attaaatagc tcgatagatt
     7201 catctttttt atcttcaact tgttctttca atgaatcttt actaatttgt tctgagctac
     7261 ttaagttctt atcagataca ggagacatac atcctaccat caatgctaag atttaaaacc
     7321 acaattattg ccactctatt tatattcctt tttactttca tacacaatcc tcccatcaca
     7381 ctaaccgctc taaagtatta ttcattgcac tagaatatat ttatattttc tttatattaa
     7441 agatttatta ttcaatacat atcaccttcc tatccaattc ttataactta ctattagtaa
     7501 aattataagc tccttaatac agaaataagg atgttatctt ttgttattaa aagataacat
     7561 ccttattttt ttgtatcaat acatatgtcc caactggtaa cttaatcgcc ccaactgtca
     7621 gtatcttggt ccaatggtat atatatattt agtataaatt tatcgatact attttcaaat
     7681 aataattctc cattatattt ttgtaaagaa gatttaatac tctgaatacc tattccatgt
     7741 acgaacttat ccattttgtt tgttaacaat atatttttat taaaagtaag ctgatttagt
     7801 ttactatttt cacatttaag tacaaaaaat gaccttgtta tagttccttt aattctaata
     7861 tatttattaa tattttcatc cactatttta tcacatgctt ctattgcatt atccaaaata
     7921 ttagaaaata tgcttgacac atctataggt tttacaaaat ttacttttga aaaatttata
     7981 gagcaagtaa atttaattcc tttttttaaa catacttcac tcttttcgtt gattataatg
     8041 tctaatatca tatttcctgt attatagata tatttaaatg tttttatttc atcttttaaa
     8101 ttgttaacat attcattaat ttctttgcta ttgtttctaa ggttgtctat acaataaatg
     8161 tgattattta tatcgtgata tagtttctta actcgcatat gagattcttg aatacttaaa
     8221 taatgcgcat attgcatatc taacttattt tttattaatt cagcttgaga ttttaatcta
     8281 ttctctttta ttatttcttt aaacaatagt ataagaaata tactactagc tcctaccaat
     8341 tttggattaa caaaattatc aaaatagtat ccttctgaat gtaatgaccc aaaccgttct
     8401 aattttttta atacataatt tacaagcata ttcattgtat taactaataa ggcaaataat
     8461 aaatatacat aatttctctt atcttggcta attaatttta tagacttcct aaaaaagcta
     8521 aatataagat atataagaat aattattaaa ttactatata tctgaatttt tatagattct
     8581 aagtgaggta ctaataagga ttctttagat gaaataacat tacctgtaat tgcaaaaaat
     8641 agtattctat atataacagc atccaagcat ttataatata cactaaatag ataaaagaaa
     8701 atggaatact taatataacc catcttataa aaataattat agtatcctcc ccaagcaata
     8761 aatgctaata tataaaataa atagtttata ttactaaagt aatttccttc attaaataat
     8821 ctacttatct gaattataat ataaataaga aacaagacaa tatagaatac tattttttca
     8881 ttttttttac tatccttttt ataaattaaa attccgttca ttatagaaaa ctgtataaat
     8941 atagataaaa ctactaatag ctcagtcata aagtttagca tattgtatca ccaagaaatt
     9001 ttaagaattt ctccttaact tctttatatc tatatctact aataggtacc tcttctccac
     9061 tttccagtat tgcagcatta ggctttatat tttcaacata tcttaaattt actataaaac
     9121 ttttatggca tcttataaat ttatatggat ttaattcttt ttctatttta cctaaactat
     9181 attttatatc aaaattcttg tttattgtgt gtattagcat atcttttttt tgaacttcta
     9241 tatattttat ttcatttaaa taaatcttat atgtattaga cttatttttt attgtaatat
     9301 gactttcctt atttatttca atatctttga tacaagttag cacatgtttt tttagttctt
     9361 ccaactctat tggctttagt aaatacctat aagctcttac ctcataacct tcttgcacat
     9421 aatctattaa tgaagttaca aatattattt ccatttcatt gtctacttct ctaatctttc
     9481 ttgcagtatc cattccattt aatttttcca tttttatatc aagaagtaat atatctatat
     9541 cttttaaatt actttccagt aactcttctc cagatatata cttttgtatc tcatattcta
     9601 tacttatatc ttttaatata ttctcaaggt aatcttctat taaaagttgt gtttcttttt
     9661 catcttcaca aactgctatc ttaatcataa aatgcctcct tacataattt ctagttaata
     9721 caattaaaat atttataata tatttaaaga taattttgta tatctgatac tttaggataa
     9781 catttttaaa ttatttttat caatactcaa tcccacacaa ctattatttg atatttcaat
     9841 ttaaagacag aaattactat aattaaaaac agtacttact gacaaaagaa gatgtcttaa
     9901 aatattaaaa aaataatttt aggacacctt attttattta tttaaacttt ttaagcctta
     9961 aataatacat taatctccta tataattgta ctacatataa aatcaacaat ataatctgta
    10021 gtacaatagc agttacagat gctccataac cactatataa atttcttatt tcaatattca
    10081 ataaatatat aaatattact actaacataa agaatacaaa catattcata aataaaactg
    10141 actttacttt atttgtttta tcagaatcac tatataattt aggaggtatg tctttgtatt
    10201 ctttcgacca tatataccat gcagatgtac ccataaaact accaatactc ctaaatacaa
    10261 gattccagcc atttgattta tgttcatcaa aataattatt ctctacatca tagtagtaat
    10321 caacagtgta ttttattttt cttggacttc ccttatgaaa ataaaatatt cctccaaatt
    10381 tatttatctt atataaatta tatcctttag cttcaatatc ttctaaccat ttctctatct
    10441 tatcaggtga actataccag tcaaatttga attttatttt cttttccata gcactcattc
    10501 tccaaaatga tatttttaaa tagcttaaaa atctatttaa ataattatat cattttgata
    10561 ctaattttag gttacaatca tatatttaaa aagctattta aatagtaata aactaatagc
    10621 cataacaccc attcctgcaa tcaatccata aatagataaa tgatgttccc cgtactctct
    10681 agctgatggc aataattcat ctagtgatat gaataccata attcctccta caattgcaaa
    10741 tacaattcca agagttatat catttaaaaa atttctaaga agtacatatc caataatcgc
    10801 tcctaaaggc tcagacatac cagataaaaa ggaataataa aaagctttct ttttatctcc
    10861 tgtggcataa taaactggta cagatacaga tataccttct ggtatattgt gtattgcaat
    10921 tgcaattgct atcggaatag ctattgtaac atcatcaaga gctgatataa atgtagctaa
    10981 tccttcagga aaattgtgaa ttgctatagc cattgctgta aatatacctg ttctcaaaag
    11041 agacttattt tttttgatat tcttttcttc tatattctcc attttcttta tttcatgtgg
    11101 attttcttct tgtggaatta gcttatcaat aacagcaatg atggccatac ctataaaaaa
    11161 agctattaca gttgaccaac ttcctaattt ctctcccata gattttgtca aagcatcttg
    11221 tgctttagga aaaatttcta tcatagaaac ataaatcata acaccagcag aaaatcctaa
    11281 gcttatagaa agaaacttag tatttgtttt tttagcaaaa aatgctatac aacttcctat
    11341 accagtagat aaaccagcca ataatgttat caaaaatgca aatattacat tattcaaata
    11401 aatcaccttc tttttaattg atattgatta tcattttctt tatgctatca tatatatttt
    11461 atatagtcaa tatttataaa aaatatacac aataaaaaag cagagatata aacttagtct
    11521 ctgctttttc tttatagtat attaaaatta tttatttaag aaatccactg catattgcac
    11581 atataaagca gttccaattt ctagagcatc ttcatctata ttaaagcatc catgatgatg
    11641 aggataacaa gcaccttttg actcatttct agctcctaca aatgctagtg caccaggtgc
    11701 tatattcata aactcagcta aatcttctgc tcctgttact ttttcaaata gtgttataca
    11761 gtcttctcca aatagcttaa ttgctgcatc tgtagctatc tttgaacatt ctttgtcatt
    11821 tataactgct ggtgttaagt acccatactc taattcagca tctgctctat atgcttctgc
    11881 tgtagatttt gctatacgtt ctaaaattcc aggaatttgc tttctaagct ctggattaaa
    11941 tagccttatt gtaccttcta agatagcttc actcgcaatt acattaaatc tagttccaga
    12001 atttaaaact ccaacactca caactaatgg ttccagagga cttacttctc tactaaccat
    12061 agattgtaga ttcataacta ttgctgaact tgcaagcact gcatcaacac cttgatgagg
    12121 aagtgaacca tgaccacctc taccttttac agtaatttta aagaaatcag cagaagccat
    12181 tcttggtcct tcttctaccg atatggtccc agattctaca tcagtccaaa gatgtattcc
    12241 aaacacactg tctacacctt ccatagcacc atcttgaatc atagctcttg cacctttacc
    12301 aacttcttct cctggctgaa aaaataattt tacagttcca ttgatactat ccttaatatc
    12361 atttaacact tttgctgccc ctagaagcat tgatgtgtga ccatcatgac cacaagcatg
    12421 cataagtcct tcatttttag atttgtattc tacatcagtg cattcaacaa cttgtagagc
    12481 atccatatca cccctaagtg ctacagtctt tcctggatta gctcctttta tagttgcaat
    12541 tacacctgta cctccagctg atacatatgg tatccctatt ttatcaagtt cttctttaac
    12601 tctctttgat gttctaactt cttccatact tttctcagga ttttcatgaa attcccttct
    12661 aagcttaatt acatagtctt tataactctt cgttatttct ttaatatcca ttccatacct
    12721 ccaagtagta cacattcttc ttatttaaaa tactttttat cacttaaata ctatattaga
    12781 tttacaaaga tacctgctat tactacagaa gctattgtaa ctgtagtaaa tcctccaaca
    12841 agcatctttg gaagcatctt atccattaaa aattcttttt cttctggtgt ttcagccaaa
    12901 gcctttactg cctcttcagt taatatatag tttggtggaa aaccataaag tgatgtaagc
    12961 gaaactgaaa aagccatttc tttactttca cctaaaagct tacctactat aatagagaat
    13021 attcccatac ctattacacc aaatattatg attcctacaa gaggaactgc catttcaaca
    13081 agcattgctg gtgtagcttt tgctaaccct gcaaatataa aagccatcaa tgatgtcatt
    13141 aaccatccaa atgaaccaga tttattaagt ggttttctat caactattcc aagttctgat
    13201 gctattacac caaatattaa acatataaca tatcttgata caacttcatt tgtaagattt
    13261 gtaaattgta ctgctaacca tgctacaaat cctaatctaa gtattatcat atatgtcgta
    13321 tcatattttt ctggtaagtc tggtattatc ttaaatctgc ttttttgttc aggtaaatcc
    13381 ttaacttttt cttcatatgt atttacagtt acttttccac ttctaaagtc tgataaaagt
    13441 ctttttcctt cttttttaag cattaatgct gtaataggat aacccgcaaa tccttgtgca
    13501 acatacatca aaattgcaag tactgataaa cttgcaagac cttttgctgt agcagcatct
    13561 gccatcatta tagatgcaac tagccctcca gtaagaggag gtgtagctat tactgctgta
    13621 tcccatccaa atactactgt ccctaatgcc aaagcaccta cacatattcc tactattcct
    13681 gccaaggcta ttactattgt tttccattga cctgctaatt ccttaatact catcatagtt
    13741 cccatatgag ttattaacaa aagcatacct aattgagcta atggtgttcc taaagcggct
    13801 aagtccacaa tattttctgg gaaaaaagtc caaaatccta ctataaatat aattgctgat
    13861 acaaaaaccg acggaacaaa agctttagtt tttgctgaaa ctatatctcc tatcgtcagt
    13921 gatactaaaa ctagacaaaa agctgttatt gcctccatac aaaatccccc ctcataataa
    13981 atatattttt ataaaatgta tgtatagtta tccattattt tactactttt gaaaaacatt
    14041 tcaagtcaaa attcgatttt tttcataaaa ttcgataaat tccataaatt aaagttagtt
    14101 ttctaaatta ttctttttgt aaaaacgtta tcccgaccat tggctattta actctattct
    14161 tacaaagaga attaaatgta atttgcaaaa aataaaacat aggatacatt ttattcataa
    14221 aacatcttat aaatataaaa tgaattgtct ttatgaatct taatatatcc tatgtttgta
    14281 agtttaatgt gtatgttagc tatggtgtaa aatttgtata ctagttattg tgtaacctac
    14341 tatatactcc atttttgttt actagctctt catgagtacc tctttcttca attcctttat
    14401 ccgtcaatac tatgatttca tcagcatttt ttatagtagt caatctatgt gcaacaacta
    14461 aatttgttct atctttactt aattcctcta aagactcttg aatttctctt tctgttacat
    14521 tgtctaaagc agatgtagcc tcatccaata ttattattgg aggattcttt aaaaagattc
    14581 ttgaaattga aattctttgt ttttgcccac ctgataattt tacgcctctt tctcctatat
    14641 aagtatcata tccatctggc aaagtctcta caaagtcatg tattctagct tttttagcag
    14701 cagctatcat ttcttcatct gtagcattag ggttcccaca aagaatatta tctcttatag
    14761 ttcctgtaaa taaaaataca tcttgttgaa ctatacctat attttttctc aatgatttta
    14821 aactaacatc ttttatactc tttccatcaa tttttatatc acccttatca aattcataaa
    14881 atcttggcaa tagattacat aatgtagtct ttcctcctcc agaaggtcca actaatgcta
    14941 tagtcttacc agcttttata gataaactta aattatccaa aacttgagtc ttatcttcat
    15001 atgtgaaaga tatattttct atctcaatgt caccttttac attttcaagt tcaataggat
    15061 ttttagcttc tttttgatgg tcttgttcca ttatctctat gaatctttta aaacctgtca
    15121 taccattttg atattgctct gtaaagttta ttaatttttt cataggttgt ataaacattt
    15181 ttacatatag tatataagca gcaaaatcac ccaaagtaat ctttcctata taagtaaaat
    15241 aaccaccagc tattacaact acccactcta agatatccat gtataaattc ataccagagt
    15301 aatattctgc cattacttta taagaatctt gtcttgctct tctaaataat ttattgcttc
    15361 ttacaaactt atttaactct tctttctcag tacaaaaaga cttagttacc ttcatacctg
    15421 ctatactatt ttctaaagta gcatttacat cacctatagt aactctactc ttcataaaag
    15481 caatattcat cttatctttt ttagctattg caaaccaaat tataaacggt aatatagcaa
    15541 atattataag cgtaagagga atatttatat ctataagtat aaagaatgaa ccaaccaaca
    15601 ttactataga aatgaataaa tcttcaggcc catgatgtgc aagttctgtt atatccatta
    15661 aatcatttac tattctagac atagttactc cagatttgtt attatcaaaa tacgtatttg
    15721 gaagtctttg taagtgtgta aatacctcat ttctcatatc agcttgcata tctacaccaa
    15781 taacatgtcc ccaatactgc ataaaatagt taagccctgc ttttgctata aatataagta
    15841 taagtgctac tgcaaaaact actaacattc ttaagttttt atttggaaca acgtcatcca
    15901 ttatatttct agttatcata ggataaacta aatcacataa ggaaaataga aaagctgcta
    15961 taaggtctag tgtaaaaatt ttcttatatg gcttataata tttgacaaat tgttttatca
    16021 taagtattaa atccctcctt tattagtact tctattagta cttctaaaaa atacccataa
    16081 attagtataa cataacaata actttaaatc ttttataaac ttacaaagta ataacaatct
    16141 ttttcataaa attgaagatt tatatcatat agttgtatac ttgaaacaac ataaaaagag
    16201 ctatatctct atattttaaa ttttataaag atacaactct atatttaata ctaaattttt
    16261 tttataaata caaaactact tcaatgcatt taatatcttt ttatctaatg ctgttgtatt
    16321 tatacctgtt atatatcctg ttgcctttat tgtaggtata tcataagttg ttggtagtat
    16381 agtagtagat acgattaaat cagcaccttc ttgttttgtt gaacattcag caattttaca
    16441 ttgctcaact tctgcttgta tattattttc tttaaccaat ctttctactc tgtcacaaac
    16501 tattgttgat gttgcgattc ctgctccaca ggctactaat atttttttca tatattgtcc
    16561 tcctacaatt tctttaatat tttataactc aaaat
//
LOCUS       DAEPXW010000084        16534 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.085, whole genome shotgun sequence.
ACCESSION   DAEPXW010000084 DAEPXW010000000
VERSION     DAEPXW010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16534
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.085"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..448
                     /locus_tag="KRM55_002760"
     CDS             <1..448
                     /locus_tag="KRM55_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1594979.1"
                     /translation="IGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICI
                     EDLQVKNMIRNLKLSRSISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCG
                     YKNEEVKDLNIREWIYPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            888..1142
                     /locus_tag="KRM55_002761"
     CDS             888..1142
                     /locus_tag="KRM55_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594980.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            1178..1501
                     /locus_tag="KRM55_002762"
     CDS             1178..1501
                     /locus_tag="KRM55_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594981.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            1775..1927
                     /locus_tag="KRM55_002763"
     CDS             1775..1927
                     /locus_tag="KRM55_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594982.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            2121..3044
                     /locus_tag="KRM55_002764"
     CDS             2121..3044
                     /locus_tag="KRM55_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBH1594983.1"
                     /translation="MVGAFVLPNYAITLSEMSNLWGNFTMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMALVSVLFFTYSIYLCATWKDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VEKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   3311..4388
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3311..3339
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            4543..4731
                     /locus_tag="KRM55_002765"
     CDS             4543..4731
                     /locus_tag="KRM55_002765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594984.1"
                     /translation="MNKIATKSRAEYMKNCRKDKRGFSVLLDKEKLDKFDEVLEEKNL
                     TKKEWLEEKIDEELEQKE"
     gene            4851..5664
                     /locus_tag="KRM55_002766"
                     /pseudo
     CDS             4851..5664
                     /locus_tag="KRM55_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            5716..5877
                     /locus_tag="KRM55_002767"
     CDS             5716..5877
                     /locus_tag="KRM55_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594985.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(6205..6669)
                     /locus_tag="KRM55_002768"
     CDS             complement(6205..6669)
                     /locus_tag="KRM55_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594986.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKNKILRERKYKKRR"
     gene            complement(6805..7122)
                     /locus_tag="KRM55_002769"
     CDS             complement(6805..7122)
                     /locus_tag="KRM55_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594987.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(7405..7701)
                     /locus_tag="KRM55_002770"
     CDS             complement(7405..7701)
                     /locus_tag="KRM55_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594988.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKNYLNRF"
     gene            complement(7720..8133)
                     /locus_tag="KRM55_002771"
     CDS             complement(7720..8133)
                     /locus_tag="KRM55_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594989.1"
                     /translation="MKVKSKRSFIVGIIVCVLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(8117..8350)
                     /locus_tag="KRM55_002772"
     CDS             complement(8117..8350)
                     /locus_tag="KRM55_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1594990.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            8569..8943
                     /locus_tag="KRM55_002773"
     CDS             8569..8943
                     /locus_tag="KRM55_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1594991.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEECFKNLK"
     gene            9555..10247
                     /locus_tag="KRM55_002774"
     CDS             9555..10247
                     /locus_tag="KRM55_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1594992.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            10443..12503
                     /locus_tag="KRM55_002775"
     CDS             10443..12503
                     /locus_tag="KRM55_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1594993.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(12709..13032)
                     /locus_tag="KRM55_002776"
     CDS             complement(12709..13032)
                     /locus_tag="KRM55_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBH1594994.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(13025..13726)
                     /locus_tag="KRM55_002777"
     CDS             complement(13025..13726)
                     /locus_tag="KRM55_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBH1594995.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(14004..15389)
                     /locus_tag="KRM55_002778"
     CDS             complement(14004..15389)
                     /locus_tag="KRM55_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1594996.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(15497..>16534)
                     /locus_tag="KRM55_002779"
     CDS             complement(15497..>16534)
                     /locus_tag="KRM55_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1594997.1"
                     /translation="YKHNIDNYIPYDQGITLDIFMYIWILGIIAISFYYLRTNFKFYN
                     YIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTRCKIIIPEKK
                     YNNKELRFIFKHELIHYKRKDNLFKLLISTICIIYWFNPILYLLKKYFHELCELSCDE
                     IVIDKCTTSEIKEYAYIILDTIKYQKTLKYSSFVSQFLNKKNIILKKRLDSMFNQDKK
                     KINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIGKINYNKNGETYGTHIIDSNGNS
                     IEPELIQTIGRGKKVGYVKKRNLYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKE
                     GIKIIGRFEIN"
BASE COUNT         6512 a         1799 c         2492 g         5731 t
ORIGIN      
        1 aatcggtagt ttaaatagaa ataaagcaag attaaaagtt gcaagacttc aagaacatat
       61 agctaatcaa agaaatgatt ttctacaaaa actatctact aaattaataa aagagaacga
      121 tattatttgc atagaagatt tacaagtaaa gaatatgatt aggaatctta aactatctcg
      181 ctcaatttct gatgtgtcat ggtcagagtt tattcgtcaa ttagaataca aggctaattg
      241 gcatggtaga caaattgtaa aggtgggtaa attctttgca agttcacaaa tatgcaataa
      301 atgtgggtat aaaaacgagg aagtgaagga cttaaatata agagaatgga tttatcctag
      361 ttgtaatgaa actcacgata gagatataaa tgcaagtata aatatattaa aagaaggatt
      421 aagactaata acaattcaaa ataaataacg tatgtaagaa ccgtaggaac tacggggata
      481 gcctgtggag aattagtaag acatatgtta gtatgcaaaa ttctgtgaag caggaaatct
      541 gtgactttag tcatgggagg ttcaggctag tattactcat tattgtattc aaaagctaaa
      601 gtggaaacct agtgaatata tgaatttaga agttaatgag agagcattag cagccgactc
      661 aatacttatt aaaattgaag atgaagaaga agcaatgaaa gaagatgaaa gagagaaaaa
      721 gagaggtaga agaaggtaga atttaaagtt aaaatagtca cattgctaat atatgaaaat
      781 gttacaattt tggaaataga tggatatata tgttgtatag tataatgtag ataatatatc
      841 accaagtaaa aaacaacaaa taaatctaaa ttatgagggg tgtatttatg gaaaataaag
      901 atattaaact tacaatatgt atatttgctt ttgtaattgg aataatagtg ttattttgct
      961 gtataggtct aggtcaattt aatatggatt gtattataaa acaaaatggt gggtcaatag
     1021 ctaccgaaca atacaacata tatttagaac aatctatttc acaatataga aattttggtt
     1081 ctatactggt tttactagga ggaataggaa tactgtttga taaaagtgtc agaaaatact
     1141 aaaaaagtat atttttattt aggatgtgat gaatgatatg gcaagagatg tatttagtgt
     1201 aaagatgaca ccactagaag cacagaaaat ggtagaaaaa aatttggaag cagatttagt
     1261 ttctgttgat atttataacc tagaaaataa taagtctata atagttacaa tctttgaaaa
     1321 atattatgca agaagcaata gtgatgcagg tttggtagtg atttgtgaaa atactacagg
     1381 aaaaacactt gttaaaatta cctcaactgg tagtgcaatt ggactatttc agattgattg
     1441 gggaacaggt aataatttga ttaaaagagt aaaaaaaata cttattgatt atattattta
     1501 attattttat gtagatattc ttaggttggt atggaatttg tactaaccta ttaagtaatc
     1561 aataaaacta aataaacata gaaagcactt acaaatatgt aggtgctttt tattgaaaaa
     1621 atagaaaata aaataaaaag taagatatag gaaaaatatg taagaattat atattataat
     1681 aattgtagca agaagatgta atctacaatt tatagagtgg agttcatgta ttaaaaaatt
     1741 atcctcccaa cgataagaag ggaggtgaat atacatggat aattttttat ttaatgtgtt
     1801 agctagtgta acagctagtt acatagttta tttgattagc aagttaatca aaaaagtaaa
     1861 aagccactct accgcaaaga gtgacttaaa gattgatata aattttaaat atcatcgtaa
     1921 aaaataactt tcagttatag aacttcactc taccgcaaat agattgtagt tcttcttgct
     1981 tttattatac cacaaattag aaaaaatatt gcatataata ttttttatag tcaataaaaa
     2041 tatgaaattt tttatacaca atgatgatga atctaactag atgaataaat ttaattgtaa
     2101 ataagaaagt acttacttaa atggtaggtg cttttgtttt gccaaattat gctataacat
     2161 tgagtgagat gagtaatttg tgggggaatt ttacaatgtg gatattagta ccaataataa
     2221 caatagtatt acttataata gctgtttctt ctatgcaata tattttagtt atgatagctt
     2281 ttttgttgat tatatattct tttatagaaa agaaaatagt tatggctctt gtgtcagttc
     2341 tttttttcac ttattcaatt tatctttgtg caacttggaa agataaatcc ttgatagcag
     2401 ataataaagt tgagactgtt aaggcacaaa gagaaactgt agaaagagaa aaagaaatgg
     2461 aaagaagaag aatacaagaa gaagtagaca aagaaagata tattgaaaaa catggaatgg
     2521 aaatatcaga aaatgattta aaagttaagc tagaggcttt agtacctcaa gaatataagg
     2581 ggaagaaata tgaattaaaa gtagaaaaat ttaaaagata tagtatgtat tttgatttaa
     2641 ctgtacaaaa tgaaaaattt agtaattctg aagaatgtaa aaaatttgta aaagaaattg
     2701 ctaatgatct taaaaaaatt aaaataagca aggcgtactt taagtttcat tcaaaagatg
     2761 acggcggtat atataattct gtttatattg attattttag aaacatacaa aataatgtag
     2821 ataatgttga aaatttagaa ttcaatgagt ttgaacttaa aaccgaagaa gaagagaagc
     2881 gagaacaaga gaaaatagaa caagaaaaaa acagttataa taactacatt caaaacagag
     2941 tggttgaccc actagataga ataaagaaac taaaagagtt gctagattca ggagcaatta
     3001 cacaggaaga atataataaa aagaaaaaag aattattaga atagataata tagtaagcac
     3061 ttacaagtat gtaggtgctt ttaaatttac aaagtattcc attttaattt tatagtttag
     3121 attttatgat ataataaaaa tatagaagtt ttgcagtgtg cgatatttgt tacaaagtag
     3181 ggcttaatac ttgaaatcta agatgttgag ggtgcgtgat aagtgttatc aattgcacta
     3241 ttgcccgctc actgcaattt taagagtatt gtatatatgt aggtattgga aatgctaagt
     3301 ttattttggg gttttagatt aactatatgg aatgtaaatg caggtagtga agcgttgaaa
     3361 ctttttatag ttacattgtt ttagattaac tatatggaat gtaaataaac ttttgaaaga
     3421 ttatgctaga aaaattcata ttcgttttag attaactata tggaatgtaa atattacatt
     3481 taatttgcat tgctttgatg acttctttgt tttagattaa ctatatggaa tgtaaatatt
     3541 tttcaatatc aatatagaac tttcatcttt cccgttttag attaactata tggaatgtaa
     3601 atcaagatat ttttaataaa atttctgagc gaactgtttg ttttagatta actatatgga
     3661 atgtaaatat ttgaaaggaa taaattttaa atgaatgaaa ggataggttt tagattaact
     3721 atatggaatg taaatcagcc aaaaacttcg aatttgaact aaaatgcgtg ggttttagat
     3781 taactatatg gaatgtaaat tctcatgact attgaataaa tataataaac aagcatacgt
     3841 tttagattaa ctatatggaa tgtaaattaa cactctctac ttgcaaatat aaatataaac
     3901 tggttttaga ttaactatat ggaatgtaaa tttagaatca aaagcactta atcctagttc
     3961 tttcatagtt ttagattaac tatatggaat gtaaatagct ttttagcttc gtctactact
     4021 ttataagcaa agcgttttag attaactata tggaatgtaa ataaaagttg cacgcctatt
     4081 tgatttttca atacattatg ttttagatta actatatgga atgtaaatga caaagcgact
     4141 attactatct caggtgataa aaatgtttta gattaactat atggaatgta aatgatgaac
     4201 aataaaacaa tcatctaaag acgaagaaag ttttagatta actatatgga atgtaaatgt
     4261 tcctgttgtg ttttttacta atcccatttt atatgtttta gattaactat atggaatgta
     4321 aattgctgtg atttcactaa taaaacaatt aataattgtg ttttagatta actatgtgga
     4381 ttcaaaatta aataaacaaa gaaagcactt acaaatatgt aggtgctttt attctgctca
     4441 aaattggtcg gttgggtaaa atcattagaa aaaattagta aaaacctctt ttctgtaact
     4501 cgttacaata ttattattaa tgtaacgagt tacagaaaag aggtgaataa aatagcaact
     4561 aaaagtaggg cagagtatat gaaaaattgt cgaaaagata aaagaggttt tagtgtactt
     4621 ttagacaaag aaaagttaga taaatttgat gaagtattag aggaaaagaa tctaaccaag
     4681 aaagaatggc tagaagaaaa aatcgacgag gaactggaac aaaaggaata aaaaataagg
     4741 gtcactccca ccgaccaaag tttgagtaac ccctatgatg tatactatcg tatatcaatt
     4801 ataatatatg tcattcctta aaaaaatcaa ttattaagga gtgtaatatt atgaaaaatg
     4861 aattaatgat gtttgaagga aaagagattg aagtatttga atttgaagga agaattttat
     4921 tcaactcaaa agatgtagca aattgtttag acataaaaaa tgttaatgag aatataatac
     4981 ttatgaatga aaagcaagtt gtaaagttaa gaaattcgga tatcagtaat actgacatcc
     5041 gaaaacttaa taatgctgga gaaaattttc ttactgaaag tggagtgtat aaattaatct
     5101 ttaaatcaag aaaagaagaa gctgagagat tccaagactg gataagcgat gaagttttac
     5161 caagcataag acaaactggt gcatacataa ctaataatgt aatcccgaaa agttgagaga
     5221 aaaagcaagt gagattgaaa aattacagtt gcttataaca gtacatctat gttaaaagaa
     5281 ttgctagatg atgcaggctt tgacaataaa tcaaaactat taacagctaa aacattatat
     5341 aagaaagcag aaattgattt accaatagag ataaacgaag aagaacatta ttttgataca
     5401 aaacaaatag catctaaact gaaaatatat tctaagagta ataaaccagc tcagatggct
     5461 gtttgtgaga ttattaaaaa gattgattta gaagatggtg aagttaaagg tgtttgggaa
     5521 attaatggtt cttggactgg tactgtaaat aaatatacaa agagtgtaat agataaggtg
     5581 agaacttgga tagaggaaaa taatagacct accaagattg caggtgagaa gaagaattat
     5641 tatgtatttt acaaaattga gtaaatttat cagttgtatt aaataattta gtttagtttt
     5701 ggggggatta atacaatgtg tgagaattta cttgataata tgtatattga aaagagaaaa
     5761 gaagaatata gaattaaact tttgaaaata agagaaacag atatagatat atataataag
     5821 ttagaaagta tagtatataa actttctgag aaaaaattag agaaaaataa taaatagaca
     5881 tataaagcac ttggatattc tactgtttca agtgcttgtt tggtataaaa tggtataatg
     5941 gagatagaga attatattaa ccaaaaaatg gagaaaatag agaagatgat ttagttgacg
     6001 ctttatcagt aggagtacct gcaggtaaga cagaatctct agtacgatta gttggagatg
     6061 gaataagtga tactcaaaaa agtttaataa ataaaagaga atttagaaat ataactcaaa
     6121 ttggtggaaa tggaaatgag aaagcattta gtgaagtaga aaacttagtt aaatagatta
     6181 gaaggtagca actagagttg gttgttacct tcttttttta tactttctct ctctaagtat
     6241 tttatttttc atatcttcta atacatctaa tgcagtagta taaaattgta tattatttct
     6301 ataaggtata gctattggaa gaatgccctt gttaactaaa aaaataagaa gtacaataaa
     6361 taaaagtgtc ataatcattc taataaaata attagtgata tctgataaat caaatgttaa
     6421 gttaattgtt gtagaaaata caacagccat aatagatata tacaaagcaa aaatggggtt
     6481 actatttttt tgtaactgtc ctttaagcct agattgctct atttctatat cttgaatact
     6541 ttttatggaa tccatttcac tataatactt ataaactttt aaataatatt ttttatactt
     6601 gtttaaagct tcttcattat ctttaaggtc tttgtcactt aactctgatt taacttcccc
     6661 aaaatccata aaatccctcc tacaatgtta tataatatac tttaatttat agcatattta
     6721 agaacttata tcagcaattt gtcgaacgat tttagctaaa aatagagtat aatgataggc
     6781 ttattattta taagatatta ttttttatat agttatatat ttctttctaa ttagataata
     6841 taatgctgtt gttataatgg ctactaatat tattgctatt attgtaatat ctaatcttct
     6901 tgtaaataag cctattgcta tatactcaag acctgttaca tagcgataaa gtacttctag
     6961 tttaacagtt tttttcttat ctatatttcc atatattgat tctaatttat taaaatattt
     7021 tttactacaa aaagcagttt taggtttaat taaatatatt attgtagttc ctattataac
     7081 tattattcca ataagtataa gattgatatt tccaaaatcc atagcagata cctcctatta
     7141 aatttgcttt tcttaatcaa agtatatcag taacacaagt acaaagagta tctaaaatat
     7201 tacaaatatt aacaggatag ataaaactat agtaaaaatt gtaataataa agcgaacgaa
     7261 aattatcata ctaaaacata agacatgtta taattgtatt agatataaga ttaacataca
     7321 ccaaagcact ccttataata aagagtgctt atttttttga aattcatcaa tatataaact
     7381 atcaagaacc ttattcaaca caccttaaaa tcgatttaaa tagttctttt tgataacata
     7441 atttatatga tataataaaa aaatagaagt gtaccaccaa tacacttcta tagctataac
     7501 taagcattct cttgctgggg gagtgctttt ttcatttctc caaacaacat tatttacttc
     7561 atcagtaatt atcaaatcaa tctcattatc tttcaaaatc tctgttgcag tacaaattag
     7621 attatctaag tcaaaacttc gagttatctc tagttgtttg ttatttactt ctctttttag
     7681 tatataagtt ttaaaataca tttatatcac cccttgtatt tactcttttt tctctaaaaa
     7741 tatattgata agtaaatatg caacaaataa aaaaatctca atgacacata gtgttatagc
     7801 tataactaga agtgattgat ttttccatgc actataagct atgatgaaaa gaaatgtaaa
     7861 agtaaataat gtataattca taattttaac taagatatga cttgttttca ttgttaagta
     7921 caagtctctt tcatctgtac tatcgtgtaa ttcttcaaca atgccttttc ttgaaaaagc
     7981 attacaaaaa ttaaagattg ctattacaat taaaagaaat gatgaaatta ggaatctttt
     8041 atcttttaaa atgcaataaa taactaaact agcacaacat aacacacaaa ctataatacc
     8101 cactataaaa cttcgtttac tctttacttt catgtttttt atcctccatt tctttatttt
     8161 cttttaaaca acatagttct tcaatcgttg taccaaacac ttgtgccata cgataggcaa
     8221 gcataagaga agggctatat tgctcttttt caatagaaat aattgttctg tttgatacat
     8281 ggactaaatc agcgagttgt tgctgtgtta gacccatatt tgttcgaaat tctcgtactt
     8341 ttgttttcat tccataacct ctttctatat gaagctaact tcatgtgaag ttaacttcat
     8401 aatatcctaa aatgagtaaa atgtcaatct cattagataa gtattataaa acctaaaaga
     8461 ataatatggt aaaaattgga tggaattatt taccttaatt ctcttgtttg taaaacttta
     8521 ttgatataga atttaacata tacataaatc ggcaaagggg cgcgaattat gaaaattagt
     8581 aaattaccag aagcggaatt aaaagttatg agatatattt gtgaagctaa caaggtatta
     8641 acttctaggg aattagttgc tgcaatggaa gaaaaatatg agtggaatga atcaactaca
     8701 tttacagttt tgaaaagatt agagcgaaga gagtttttaa gtacagagaa aataggcaaa
     8761 cttacacatt ataatatact agtaaaagag aaaaaatatc taaggtttga aacaaaggaa
     8821 tttttgaaga acatacataa aaattcaatt tcaagtttaa tgtcagcgtt acatggtgaa
     8881 gacgacgaag tggatgaaga taaattaagt gaactcgaag aatgttttaa gaatttgaaa
     8941 taagaaaatg acaaattgat acataataaa taaaatgaag gtatgaaatt ataacttttt
     9001 ctaccttcat tttgtttatt attctgaaca tgttaagaaa atgaaataag tttgtatttt
     9061 agttatataa attttaatag aatatgtaca gtatatagta gatagaatgt ataaaaatag
     9121 aatttaaata agtagctatt attgcagtga aatgaatgtt tctaagtata tttgggtgga
     9181 agaatggtgg aagaaaatta gtgaaatgta attcttccac cattcttcca cctagaaaat
     9241 agaaactgtt taataagaat taatatacat taattcagct gaatgcaatc aaaatactta
     9301 aatgaaagta atctgaaaac aacataattc aaatcaattt attcaaataa acctcaattt
     9361 atcttaaatc ttaagaaata tttaagaatt aggataatat tttcttaaga tttatatttt
     9421 attatatagt tataagggaa agttacaaaa atgtaagcca aagtaatata acaatttagt
     9481 cattgttgag aaagggagtg aaagatattg tataatatag ataagtatta ttatacaata
     9541 gaggaagtga aaatatgtac aatatattag tagtagacga tgataaagaa attgttgatt
     9601 cgatagaaat atatcttaaa tcagaaggat ttaaaatata taaagcatat gatggaatga
     9661 aagctttgga aataataaca gagaatgaca ttcatctaat actaatggat ataatgatgc
     9721 ctaaattaga tggaatcaaa gcaactgtaa aaatacgaga agaaagaaat attccaataa
     9781 ttttaatttc agcaaaaagt gaagatacag ataaaataat aggattaaat attggagctg
     9841 atgattatat aacaaagcca tttaatctat tagagcttat agctagggtt aaatcaaact
     9901 taagacgata tgtaacttta ggtaattatg aagatacatg taaagaaatt ctaaaaagtg
     9961 gagctttgga gttaaataca ctaacaaaag aagttaaaat tgatggtgaa aacataaaaa
    10021 tgactccaat tgagtataaa ataattgaac ttcttttaga aaataaagga cgagttttct
    10081 caatagatga gatatacgaa aaagtatgga atgaggaaag ttttaattca gaaaatacag
    10141 tagcagtaca tatcagacga ataagagaaa agattgaaat aaatccaaaa gaaccaagat
    10201 ttttaaaggt ggtgtgggga gttggttata agattgaaaa attttagtgg aaaaattata
    10261 aaagaaaaga gtttaatatt taattgcatt ttgattttag tcatttttac atttacacaa
    10321 atgttaggaa ttttaatatg ttttaatttt ttctctgaga gtttaattta ctctatgggg
    10381 attatgcttt tcttaaactt tattttatat aaaatactga caatgtagat gaggtgggca
    10441 acttggagaa atatagagta ttaaagttag tttcattaat cataatatct atctcatttc
    10501 cattaactat attgttggtg acaataggac ttgctgagcc taaatacaat atacaaaaaa
    10561 cttctacaaa gagtgggatt tttgatatat ctgatgattt ttatgatagt aatatatttg
    10621 acgaaggaac aatggcaagt ctattaccca agtttaagct atctgtaggt ggtaaattaa
    10681 ctagtaaaga aaaaggtaaa ttccaacaag aaggtaaaag tatagattta agtagtagtg
    10741 attctgagta tgataaaatc atgattaatg aacaagcttc tgaagaatat ttaagttatc
    10801 taaaaaatat aaaagtgtat gttattaata catacacagg agtattttat acaaatacgt
    10861 catatgctag tttatatgat tttaaacaaa aaactaagag ctattgtaat gtagagataa
    10921 taaataagat aggaaagagc tcatatatta aaacaataaa tggagaaaaa tttgaactga
    10981 ataatctgag tctggaacta aatgaagtag atgaaggttt tgaggcatat gtatcttttc
    11041 cagaagagcc aactatagaa gatggaatag tatatactaa ttttcaaata tttaaacaag
    11101 ctacagaaaa agtaagatta ttttttgtag ctagtttaag tttagcaatt atatgtttat
    11161 tatctataat tttatatatc aaaataaaag gtgaagtttt aaaaagaaat aatgtatttt
    11221 tactaatata cagtaagata cctatggaat ttaatgtaat attagtatct atttcaattg
    11281 caattttaac tatatatgct cttgctgtat cttatcatat tgatgtaatt gcattagttt
    11341 ctttatcttt actgatagta tcaaataata tattttttat aaatgtgcaa ttgagttatt
    11401 tagaaaataa aatgtgtata tttaagacaa gtattatagt aagagtgatt ttatggttaa
    11461 taaaaactgt aagggaggtc agtaacgcta taaagaaagt atctttagca aggaaagtta
    11521 ttgttatagt gataatatct ttagctttaa tcatggtaat tagcactcga agtataggta
    11581 tgggattact gttttctata tgtatttttt taggatttac aatatatata actaaaagac
    11641 tttcatatct tagttacgta atagaaggta cagaaagaat aaaaaaggga gaattagatt
    11701 ataagataaa aattactggg aatgataatt ttacgtcttt agctgaaaat ataaataata
    11761 ttggagaagg tcttgataga gctatagaag agcaagtaaa aagtgaaaga atgaagtctg
    11821 accttataac aaatgtatct catgatttga aaactccact tacttctata ataaattatg
    11881 tagatttaat taaaaaagaa gaatcaatac aaccagagta tataaatgat tatataaatg
    11941 tacttgagtc aaagtcaaaa agactaaaat tattgataga agatttattt gaagcgagta
    12001 gagtaagtag tggcaatata gaattacaaa ttagcaagat tgatttagtg caactattaa
    12061 gacaaagtat aggtgaactt gaagaaaaat tatctaaaaa taatttatat ttaaaattaa
    12121 atgttccaaa tgataaggtg tatatatggg cagatggaag aagaatgtat agagtatttg
    12181 aaaatctttt atctaatata gcaaaatatt ccttagaaga aactagagtc tatattgatg
    12241 tatatgacta tggtgaaaat gtaaaggtaa ctatgaaaaa tatatcttct tatgaattaa
    12301 attttgaccc aagtgagatt atggaaagat ttaaaagagc tgatgaatca aggaatactg
    12361 aaggaagtgg attagggctt gctattgcaa gagatttagt agctttacaa ggtggaaaat
    12421 tttatataga aatagatgga gatttattta aagcaaattt agagtttcaa aaatatgaag
    12481 aagaaataac aaatatggaa tgagatagta tttaagtata tatatttttt ttactgtcga
    12541 aagcttttat tataatatat tagaatattt acagtagaga atgaagagta aaaacagagt
    12601 aactttaagt cactctgttt tttatttaaa atcaataata taacaactta aattaaaatt
    12661 gtacacatag ttttaaaata acttatacaa taaaacatta tccaaatatc acaagataat
    12721 tccaaataaa tatatagata tcactcctgt aataatagaa ataccaatag atttaaactt
    12781 atatgcaaca agaagtacaa tcataaaaga tataatttta gggttagcta tagataaata
    12841 tagactatct ccattaaaaa atacatcttt agcagttaag gaagtaagta ttgctacagg
    12901 tataaatttc atgatttttt tcaaaaaatc aggcatctct ttttttgaaa aaattaacat
    12961 aggaagcact cttggtagat atgtaacaat gtacattcca attataataa aaaatatata
    13021 attattattc ataagattcc tcctttttac agtaagattc ttctataaag aaaccaatta
    13081 aagatgctaa aattgatgca actattatta ctaaattgct tttgaataat gcatataaaa
    13141 taacagaaat aatgattgat gatataaata ctacaatata aatcttattt tttatttgag
    13201 aaactattaa agctataaac atagaagtca atatgaagcc agaaatagaa ctgtctatag
    13261 atatactttc tcctaaaaat gctccaataa aattagctaa aactgatgaa attaagcaga
    13321 agaaattaag ataaatagca tttctatcag accaatttcc agcagtaaat ttttcataat
    13381 taactgcaaa agtttcatct gttatagtat gacaaaatgg caatataaat tttggacttt
    13441 tattttttat gtacatgttc aaattagaac tcattagaaa atgtcttaag ttaactataa
    13501 atgtagtcaa aacaatagat gttacacttg caccagtaga aatcattgaa gctgcaatga
    13561 attgagaact tcctccaaat actaaagtta ccattagtgc tatttgaaaa ggtgaaagac
    13621 cagatttttg taatagtatt cctcctacta tacctatagg tatataacct aagaatatag
    13681 gaattgaagc aataaagctt tcttttaatt gttgagttct ttccacaata aatcactcct
    13741 tttgtattaa atgtattaaa gtattagtaa aacagaaaaa tagattaatt gtataattgc
    13801 aattataatt aaaaataaat ttggattaat gtataaaata ctatacaaca aataaataat
    13861 cttaaacggt tattaaattt tatctatttg ttattatgat gtaataatac atattaatct
    13921 ctataagtta attactatct ggtgtaattt tattttaaca acaaaaaaaa atacacacaa
    13981 ttaaaatatt gtgtgcaata caattatttt ttctcttcta atagtctttt taatacgctc
    14041 aaaccagctt taagttcttc tgtactttct gtagcacata cagctattct tattgcagaa
    14101 attggttttt cttttccaac agcaaaacgt tcagaagcat agacctgtac accttcttta
    14161 agtgcttgta tctcaaattt ttctgccatt attccatcag gtagaatcaa ccatctaaat
    14221 atacattctt catttcccaa aagattatat ccagataaat attgattaat aatcttgttt
    14281 cttcttcttg cagatttacg gcgtgcatta attaatttat cggcttcacc tgatgtaatc
    14341 atgcgataag caatttctgt taaaaaataa gattgagata gattaatgtt gtataatgcg
    14401 cttgataatg cctctcgata ctgtttaggt gtagagatat atgctagccg taaactaggt
    14461 gcaataattt ttgataaact cgtaatataa attgtttgat tgggcagata ggaagccact
    14521 ggatttaaat gtgtttcatt aagtaaacta tgaatagcat cctcaataac aattaaattg
    14581 tatttagatg caatatttgc aatcattttt cgtccatttt gtgacattat atgtgtagtt
    14641 ggattttgat aatctggtat tatgtataga cctttaatat tttcattttt acaagcatat
    14701 aatagtcctt cttcactaat ctcattatct tcttgtttaa ttggaattag ttgaatccca
    14761 agcattttag ctgctgtctt tattccagga taagttaatg ggtctacacc tattctatct
    14821 ccatgttgaa acaaaccagc taaaatggca acaattgcat tttgtccacc acttgcagga
    14881 agtaagctat ctgatgtagt ttcaagccca gctttataaa ttaatttggc aatagcttct
    14941 ttttgccatt tagcaccatc tctttgtcca tattggaata tggttttaaa atctatttcc
    15001 ttaattatgt gtttaaacaa agtattcatt tcttctagcg tgaaatctgg attcattgtg
    15061 cccatttcaa taaatgtaat tttattatta ctggacatca agaatagatt tgaacgtgta
    15121 tcataagata caaaagttcc acttcctgta actccactta ttagaccttt tttttcacaa
    15181 attttaaaag ctctagagat agtactcaca ttaacatcta agaaatctgc caattcacgt
    15241 tggggtggta atttagtacc tggtaataaa aatccattgt tgatatcttg ttctagttgt
    15301 tctgcaagag ccttatataa tatttgacct tttgaaggtc tctttggttt ccagttcata
    15361 ggataatttt caaaagaatt aattggcata agttttcacc tcacattatt aatttgattt
    15421 tttctttatc taaaacaata aattctaaag atacaaataa aaactgatag gaaataattc
    15481 tatcagtttt tgtcttttaa ttgatttcaa atcttcctat aatttttata ccttctttat
    15541 cataaagagg gattgttttt ttaaatatat taaaatttct ttttcttgta tataaaacag
    15601 cttcttctgg tgtctttggt tgattatcac aatcgtacaa atttcttttt tttacgtagc
    15661 cgactttttt acctctacct attgtttgta taagttctgg ttcaatggaa tttccatttg
    15721 agtctattat atgtgtacca taggtttctc catttttatt ataattaatc ttaccaatag
    15781 tatattctac atcttcattt tgtttaaaat tggagttgat agaaaatatt gaccctatta
    15841 ttataaaggt taataaaaac ttaagaccta aattaatttt ctttttatct tgattaaaca
    15901 tagaatctaa cctctttttt aaaataatat tttttttatt tagaaactga gatacgaatg
    15961 atgaatactt caaagttttt tgatacttta ttgtatctaa tattatatat gcatactctt
    16021 taatttcact cgtggtacac ttgtcaatca caatttcatc acaagataat tcacataatt
    16081 catgaaaata tttttttaat aagtataaaa ttggattgaa ccaatatatg atacaaattg
    16141 tactaattag aagcttaaat aagttatctt ttcttttata atgaattaat tcatgtttaa
    16201 agatgaatct taactcttta ttattgtact ttttttctgg aattattatt ttacagcgtg
    16261 ttaaacctat aatggcagga gaataaatac ctttaacctt atatatttga agttttttat
    16321 ttatacttag ttcttttgct tgttcatcta agatactagt aatatctatt tctaaaattt
    16381 cttttttaaa attttctatg taattataaa atttaaaatt tgttcttaaa tagtaaaaag
    16441 agattgctat aattcctaat atccagatgt acataaatat atctaaagta atgccctggt
    16501 catatggtat ataattatcg atattatgtt tata
//
LOCUS       DAEPXW010000085        16308 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.086, whole genome shotgun sequence.
ACCESSION   DAEPXW010000085 DAEPXW010000000
VERSION     DAEPXW010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16308
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.086"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(184..669)
                     /locus_tag="KRM55_002780"
     CDS             complement(184..669)
                     /locus_tag="KRM55_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1594998.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     regulatory      complement(752..845)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(1190..1573)
                     /locus_tag="KRM55_002781"
                     /pseudo
     CDS             complement(1190..1573)
                     /locus_tag="KRM55_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      1799..1896
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1951..2127
                     /locus_tag="KRM55_002782"
     CDS             1951..2127
                     /locus_tag="KRM55_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1594999.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            2353..2553
                     /locus_tag="KRM55_002783"
     CDS             2353..2553
                     /locus_tag="KRM55_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1595000.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     repeat_region   2917..3405
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2983..3011
                     /rpt_unit_seq="ctttacataccacatagttgatataaaac"
     gene            3632..3814
                     /locus_tag="KRM55_002784"
     CDS             3632..3814
                     /locus_tag="KRM55_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBH1595001.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIIF"
     gene            3885..4730
                     /locus_tag="KRM55_002785"
     CDS             3885..4730
                     /locus_tag="KRM55_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1595002.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(4954..5118)
                     /locus_tag="KRM55_002786"
     CDS             complement(4954..5118)
                     /locus_tag="KRM55_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595003.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(5659..5991)
                     /locus_tag="KRM55_002787"
     CDS             complement(5659..5991)
                     /locus_tag="KRM55_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBH1595004.1"
                     /translation="MNTREMKEYRVFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(6235..6876)
                     /locus_tag="KRM55_002788"
     CDS             complement(6235..6876)
                     /locus_tag="KRM55_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBH1595005.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(6857..7150)
                     /locus_tag="KRM55_002789"
     CDS             complement(6857..7150)
                     /locus_tag="KRM55_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1595006.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            7543..7602
                     /locus_tag="KRM55_002790"
     CDS             7543..7602
                     /locus_tag="KRM55_002790"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH1595007.1"
                     /translation="MTEYIYYYNNKRIKKINLA"
     gene            complement(8118..8870)
                     /locus_tag="KRM55_002791"
     CDS             complement(8118..8870)
                     /locus_tag="KRM55_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH1595008.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(8929..10584)
                     /locus_tag="KRM55_002792"
     CDS             complement(8929..10584)
                     /locus_tag="KRM55_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595009.1"
                     /translation="MEYFSESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     YQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(11857..12936)
                     /locus_tag="KRM55_002793"
     CDS             complement(11857..12936)
                     /locus_tag="KRM55_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1595010.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIFNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(13020..13676)
                     /locus_tag="KRM55_002794"
     CDS             complement(13020..13676)
                     /locus_tag="KRM55_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595011.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            13998..14204
                     /locus_tag="KRM55_002795"
     CDS             13998..14204
                     /locus_tag="KRM55_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595012.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCLAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(14357..14785)
                     /locus_tag="KRM55_002796"
     CDS             complement(14357..14785)
                     /locus_tag="KRM55_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH1595013.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGDMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(15261..16199)
                     /locus_tag="KRM55_002797"
     CDS             complement(15261..16199)
                     /locus_tag="KRM55_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH1595014.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
BASE COUNT         5656 a         2633 c         1721 g         6298 t
ORIGIN      
        1 tgtataaagt ataagttaaa tctactttca attaaattta ccatttataa ttactttata
       61 ataaaaataa attagttaat ttattctctt tagttctgtt ataatgtttc tacaaaaaag
      121 aatcccatta atgggattct tttttgcgat ttattaatat atttaaagct tgctagtatc
      181 gtattataaa cttaaatgct cttctatgta ttgattatat acatatccag aatatcgttt
      241 ttcattttta ttgatattaa ctcttgccca ttttccaacg ctataacata cttcaacttt
      301 aaaaccatca gggattgtag ttataacttt agattctaat gttctatcat ttctaagttc
      361 taaacttaat ccatttgttc ttatatttcc tatgtaattc ttttttctat tttttattgt
      421 atcattacta ttgtttttag cattacttaa tctttctaaa tatttataaa gtaaccaacc
      481 tttgtcataa ttactctcaa cttctgccca tattccatct acacacttta acttaacaat
      541 tttaccttct ggtatacttt ttaatttcaa actatttatg tctggttttt ctcttaaatt
      601 caatttaatt ttagtcttaa aattgatgct agatttgcga aaatttttta acattaattc
      661 agatatcatc ttaagccctc ctcttgccaa atattaagtt attaaaatat ataactctaa
      721 aaatactttt aacaaaaaga attattatct ttttggcaac tggctgacat gacctttatt
      781 acataaagat tttagtccct atagttttgc gtcattagat ttatctaata ttgcctatat
      841 ctgaataata acataatttg aacaattaaa aaataatatt acctcaaatt ttatattatt
      901 taaatataaa ttaaattttt aattaataat aatcaaaaaa tatctttata tttattcaat
      961 tactgttctt tatagtcaat ataaaagaca gtaatttatc tatagtgtta cttatatttt
     1021 atatatatgg ccatttttca acattttaca atatatataa catttatttt tttaactttt
     1081 gtcagcaaaa cactttatcc acaattttta tataagtttt ccacagctta tccccaacat
     1141 tatccacata aaaaaggtag cacttatatt attagctacc ttttatttat taatcttcat
     1201 atttccagct ttttatccaa cttcctattt ctattatttt ttcttcagtt atttcttctc
     1261 catcatgtaa ttttgaaatt aattctgata aaggattgtt atgtaaacct ctaaaaactc
     1321 tttttccctc tattttgaga tattctctct cttttattaa tactgtatag tgtacatgcc
     1381 tcccaattct ctatgatatt aaaaaacctt ttttggttaa tctagctaaa agtataattg
     1441 tagttgtatg cttccaacca tatgtttttt ctatttcatc tgcaacatct tttgatatta
     1501 cagttttata accagtatgc catatgcatt tcataatttt taattctgta tctggtaatt
     1561 ttttatttag cataatatat tccttctttc aatttatgtc acttcttcaa atttatctag
     1621 cttaaattat aataggagct ttttagaaca aaaactatat ttaattttta ccaggtactc
     1681 tacgtgttta gtctgttttt aagtgtaaaa taatgttcat atctataaat ttatttaact
     1741 ttcaaacaat cctgttgaat aataactaat tctattgtat tattttagtt gtagaataaa
     1801 actaaatcgg caaaactaga gaaatttagt gacgcaaagc tatagggact aagacttata
     1861 taaatatctt atgagttatg tcagccagtt gccaaagaga tagtgttctt tttgttttta
     1921 tgaaagtttt ttagggggat aataatttat atgtttggaa ataaaatgga taaatgtaca
     1981 catgtattga ctgcttatat tagcagttcg tatgattatt gtaatttttt agatacacag
     2041 ttagatgatt ttatattaga gtacggagaa aatgtagtag agtcttgttt acaccaagta
     2101 atggtattgg taagtaagta taattagata gacattgatt tctagagaac cctttttagt
     2161 tttatctaca tttatattaa tatatagcaa tgtaaaacgt ttaaatatat ttttaatatt
     2221 aagaataatt aaaatgttaa ctaaaaaata taattaagta gacatttcta ttaatctatg
     2281 atacaatagt atttgtggta atacacaatt aaatcaagta tatcttgata taggttaata
     2341 ggagtatttt taatgaataa tggaatagtg aaatggttta ataatgaaaa aggattcggt
     2401 tttatatcaa tggaaggtag agatgatgtg tttgctcatt tctcagctat acaaacttca
     2461 ggatttaaat cattagaaga aggtcaacaa gtaagctttg atatagttaa aggtgctaga
     2521 ggtcctcaag cagaaaatat aactatatta taatatatag atttttcggg aaagactctt
     2581 tttagagtct ttttttattg ttaatatatg taagataatc attggtgaag taaataaggt
     2641 atattgagta atgttcttga tagtttatat gctaatgaat ttcaaaaaaa taagcactcc
     2701 tataaaaaga gtgctcttaa tgtaaatata aaccttcatt ggtccagcct aataccccgt
     2761 attctccaag ttctaactct tttttatata cattatcact ttcagccata tctaacacaa
     2821 tcatttcttc tttagaatca atttgtaaaa tatgaggact gtgtgttgtg acaattattt
     2881 gtgtttttgg gagaattgtt tttaatgtaa taaaaatttt acataccaca tagttgatat
     2941 aaaacttaag actagcagac tcataagcaa ttagttgcct ctctttacat accacatagt
     3001 tgatataaaa ctttaataat aaggagagaa aaaatgaata tttatgactt tacataccac
     3061 atagttgata taaaactaat tggagtccaa tctaatttaa tagaaggaat actctttaca
     3121 taccacatag ttgatataaa accctattct tatatttcaa atcctttgag tgcttatgct
     3181 ttacatacca catagttgat ataaaactaa aataactgaa caagctaaca gacaagattt
     3241 agatctttac ataccacata gttgatataa aacctttgaa aaggtaacag agaaactaaa
     3301 tgtatcttat ctttacatac cacatagttg atataaaacg tatgtttaga tatttttttt
     3361 atatttgttt tttgttcttt acataccaca tagttgatat aaaaccccaa aataaactta
     3421 gcatctccaa tgtttacaca tatacaatgc tcttaaaatt gcagtgaacg cgcaatagtg
     3481 caattgataa tacttattat atattctcaa tgccttatat ttcaactgct aaacctcaat
     3541 ttgtcacaaa tatcgctcac tgcaaaattt ctatattttt attatatcat aacatataat
     3601 taatattttc aattaatttt tacatttaat tatgtttaaa ttctataata atgcaacttt
     3661 aatgtttctt tctggaacta atataaaaac tatttcagaa agattaggtc atgcagatat
     3721 aaaaataact atgaatagct actctcagtt tttagaagag atggacagag aagcatttga
     3781 aaatttgagc aaaatactat ttattatatt ttaaagaaga tgacttattc aatatttgat
     3841 gctagaatat aattaataaa aatttaatta taggtgattg tattatgaat attattaaaa
     3901 gcataacttt actcttaaca ttattaattg tgatattaat gacaggctgt tccccaagag
     3961 aaagtgctag tgaagttgca aaaaaatata ttgataagat gaactctggt gactatgaaa
     4021 cagcatatag tttattaagt aaagatagta aaaaaaaaat tagtatagaa aatcttgaag
     4081 aatttcaaaa tattttagtt agtacaaaaa gaataattag ttataaaata ggtaaagaaa
     4141 aaatcataaa aaaatataaa catgatggaa aagaatataa aaatgttgtt aaattagaag
     4201 aaacttttaa tataaaaaac cttctttata aaaaagatga ttctctaaaa gtaaatagat
     4261 attttgtagt tgaaaataac aaatacaagc tattattgta tgaaagtttc aaaaaagaat
     4321 ttggtattaa tagtatggac cttgctcaac ttaagcttaa tgattttgga ctaaaatact
     4381 ttaaagaagt tgaccttata ctaaaaaaag ctattgctat taatcctact gattcaaagc
     4441 tttattatgc ccaagcatgt aattatatga attttgatgg atttcctggt tattcagata
     4501 caacatataa tgctttagat tcaattaata aatctttaaa gtatttagat aaaaatgatt
     4561 ctgactacaa aaaaaatgca agtaatatat ataacttaaa aggagttatt cttatgtttc
     4621 acaaaagatt tgatgaagca caacaatatt taaataaagc cttatacttt aacaaagata
     4681 atgaagaccc aaaatataat ctaaatacaa taaaaaaaca tctaaactag atatttaatt
     4741 tttgaattta taaaatattt ttttatgtat aattcagcac tgaatcataa tctctactaa
     4801 actaattaca agtttaaatt ataaagactt atttctatat aaatattact ctataacaat
     4861 aagtttctta tttaaatttt aaaatattat ctaaaaatca taaaaaagaa ggtataaaga
     4921 gctaccctca agctcaatat accttataaa tatctaaact tcatttttta ctaatttttc
     4981 tatatctttg ataatatgtt ctttagattt ttttccagct atggcatcaa aaattgcaac
     5041 agcctttttc tctccaaact tttctgctac atcattaaag tctaaaaatc taacactttc
     5101 ttttggttta ccaaacatat aacacctctc atacattttt atatatttat tataacttct
     5161 atagacttat ttttcaccaa taaacgttag acaaattagt ccctttattt ttttaaacta
     5221 gctttacctt caaaattctt aacaaaaaca gtttattcta ctctataaat aaaaatagac
     5281 aatttaattt gtaggaaact gataatagaa tacagtaaat aaaactttgt ttaatctatc
     5341 tgaaaaagtt atctattaaa actgctatga atttataaag aatattctag ttcataaaaa
     5401 tacaaatatg taaatataat caccttaata ttaatttatt taaaataaaa aatgtataaa
     5461 agatttaata atgacaatat actattctca atacaatcta tgatgtaaat aatttaaaac
     5521 tgctatatta tttaaaaatt tatatttata tatgcaattc taaaaactta ataagaagtg
     5581 aacttagaaa ataaagctta atttcaaaga cttaaataga ctattattat tagtctaaat
     5641 aaactacgtc tatcaaaatt atatattaaa ttcttctaaa atttttattg caaatcttgc
     5701 gtttggatat gtaatagacc cgccaccaat tacacctatt tttatagctt ctataatttc
     5761 atctttactt gctccagaat taatacaacc ctcaatatga taacaaatac actcatcaca
     5821 tcggcttaaa attgaaatag ctagtcccat taattcctta ttttttttac ttatagcccc
     5881 ttctgaataa gtcttatcat caagacttcc aaatactcta aaaaactcat ctgtttcgct
     5941 taatttttta ttgtaaaata ccctatattc tttcatttct ctagtattca tcttctacct
     6001 cctatgtttt tcttataaga atatcacacc gtacttatat tttcaatatt aaatacaaat
     6061 tttcatttta tgttcattag cctaatttat attatttttt gaaatctcaa taagttatca
     6121 tataagtaag attttttcag aactaaaata gaaatcttag taatttcttt attatctatc
     6181 tcagttctga aatatattat tcttatccaa acattattat agtgattaat tatattagtt
     6241 atttttacct gaaattttat acatcaaata agaatatata aatggtagta ttacaattac
     6301 aaagattaca aagatattat aaaaaggaat attaataaat gcattaataa ttaataatat
     6361 tccaccaata agccaaatcc atccagctaa atggtgtgtc ttattccaat tatcttcatc
     6421 attaagagtc catggtaaaa ttattcctac tgagtaattt cgtttacatt taggaagata
     6481 gtttccaaat aaaataacta ttattcctaa aattaatcct gtataaaaat tagactccaa
     6541 actaactcct gttgaatata aaaccatcat tatttgtata attactgaaa gtatagcaac
     6601 tccccatttt gataaatttt gtataacatt tgaaaaatta gctttcttag gctcattctc
     6661 aagtctaaac catgtataca aatggataca tagcattaac aatggtacac caaaagctgc
     6721 tataaccttt ggagcataat tatctggatt tccataatta tcaaaatgaa ttgcaacttc
     6781 atttggtaat ctattataaa aatatattga tacaataaat ggtataaaac atattaaagt
     6841 agataaaata aattgtttat ttatcgcttt tttcattatc tttttctccc ttctccataa
     6901 attgtgaaaa ccaaagcatg acctcttcga aaactgaaat atttatttcg tagaaaataa
     6961 agttcttata ctttgtttca aatatgagtc ctgccttttt tagttgagat agatgataag
     7021 aaattgtagc attcgtcata ttaaattttt cactaatttc tcctgctgac attttattct
     7081 ccctcaacat aaccaatatt tctcttctta tagggtctga aagagctttg aatgtttctg
     7141 gaaaccccaa caccatcacc tcgctattta gaatttcatc taaatataat ataacataac
     7201 atccatttta tttcaatagc tatttagaaa tttttctaaa tagttatttc taaatattta
     7261 ttgaaaattt ttatattaag attctcaatt tacttaagtc gcttttattt aatcttactt
     7321 tatctaattt ttttaactta acaaaagtgt attgcaccat aattgttaaa gcaaaaacct
     7381 aatgattgag gtacttatat atataacaat acttttaatt ttaaattaaa agtagctaaa
     7441 cccaatttaa aaagtagtta agtcctattt aaatagaaaa gaatgaaacg agaaatatac
     7501 tgtataaaag tacataaaaa catctactaa ttagatacaa ctataacaga atatatttat
     7561 tattataata acaaaagaat aaaaaaaatt aatttagcat aaccttgtta aatatagatt
     7621 tgaatatgaa tttaaagtta tgtaaaatta aaaatacagg aatgaaaatt ccattcctgt
     7681 ataaaatcta acttttgagt ctcagtacaa tcttattttg agacaatctt ttttgtttta
     7741 tattttctta tatttaaaat ataacgcata tcttatgcaa catattcata tttttcttta
     7801 tattctttca tcgcatcatt ccaagcgtct tgtactgtta cacctctttt attagcaatt
     7861 ttttgtgcca gttcaattat cttcatagct cttcttgata tgttcataaa cattcctcct
     7921 acaaattacc atatatttca tatatataaa tcaaggttat atttttatga tatataatcc
     7981 ttctattgta agattacagt ttatatgtgt attatatatg aactatatta gaagataatt
     8041 agaattttta taaagctata tgattagatt aaatataaaa gctttacaat tacttataaa
     8101 tttaaaaagt ctataagcta aactaatgtt tgatatacca attttacgac cataaataat
     8161 gccattacta aaaatattgg ttttatcatc tttgaacctt tctttatagc aactttagca
     8221 cctacataag ctcccattat catcactaat gcaaacacta tagcaatttt ataatctact
     8281 tgaccattta tcatgaataa taacaatgaa gttatattac ttgttaagtt taatattttt
     8341 gtatttgcag aagcatgtaa aaaatcatat ccatatattt ttataaatcc aaaagtcaaa
     8401 aaagttcctg tacctggacc aaaaaaacca tcataaaaac ccattataag agccataagc
     8461 atccctaatc ttaaattttt cttattaaca gcttcaaaat tatcttcttg acctaaattt
     8521 ttagaaataa aggtgtaaat agccactatt aaaatcataa ccacaaccaa aacatttaat
     8581 atctcttcac ttattgataa tacacatctc acacctagaa cactaccaat aatagtaaat
     8641 ggtactaatt tttttaaaag gttgttatta atttttccag actttgcata tctataggca
     8701 ctacttatac atcctgctga tgctgcaaat ttatttgtac caatggcaag atgtactggc
     8761 actccaattg ccataagaac aggcatgctt ataagtcctc ctcctcctgc tatagaatct
     8821 acaaaagcag ctaaaaaccc ccctatacat aaaaaaataa ctgaaaacat aaaattcctc
     8881 catcattctc tttcaatttt tcttacaata tatattatat aatcttattt aatacttatt
     8941 atccagcata ttctttctat attcatttgg agttatacta ttaaacttct taaatatttg
     9001 tgaaaaataa ctactgttat taaaacctac tttcttacaa atatcactaa tactcatgct
     9061 tctatctaac agatattttt tagattcttc tatcctaaga agatttatat actcagttat
     9121 tgaaacttta tttctttcat taaaaataga actcaaataa tttggactta taaaaaaaac
     9181 atctgatata ctattcaaat ttatattttc tttataatat ttttttatat attcgtttat
     9241 attttcaatt agatttcctt tatcttttct ccaaaatgct ctattcttat caatacactc
     9301 tttggaaaat tcaaataata cattccataa atcttcatca ctgtttacaa gtgatatttt
     9361 tttattatat ttatttctta aataagatat aagttttaaa tcctctaaat ctctaagcac
     9421 tgttctagac aatacaaata tcatttcctg aatagtatct ctaacatcat tatatcttaa
     9481 tttgtttgta tctattagat tataaacacc ttctaaattc atatttttaa tttctttttc
     9541 aatataaagt tctaattcaa agggatattc ttttgaagaa ttattgaaca tatctatcgg
     9601 attaataata tactcttctt ctaataatct actatttgct tttttaagtg cctcttcaag
     9661 tcttatattt tcttttctac tcttcaatat ctcctcatct tttatactaa gttgattttc
     9721 aaaaaaattc ctcttagcta tttcctgaat aaattcagac atcattaata aattttcttt
     9781 taatacatat aatctacttt taggatttaa tggaaattca ttgtaaattt tgtttatgta
     9841 ttttatatca ataccagaac tacttgataa ttcagataaa tttttatcta tatcaataga
     9901 cttatatact ataaaattac cacattctat atatccaact atattttctt ctaatactat
     9961 aggtatctct aaactggaaa caccatactc acaatggtac actttttcaa agttatcatt
    10021 atttatgctt ttaacaagtt ttttagtaca ctgttttata tttttacaaa tatcgcaaaa
    10081 tttattttct ttcttagtct caaatatttc tttatacttt aagtcatata cagatattct
    10141 aagcttcaat atattagata tttgatttgc aagattttca attatgttta cattaactaa
    10201 ctcctgtata ttgttttcag aaaatactat aggtatttgt ctcaaactcg aaaatttatg
    10261 aggaacataa gtaattaata ttactaaatc aattttacca gtgtttataa tttcatgttc
    10321 tgaatatggt gggcaataaa ctatagatgt ttcctttata ttgacctttt taccatcaat
    10381 tatttgtatt ccttctccct gaatcacata taaaagctgt tcttcactta aatgaaaatg
    10441 cttttcttgg tagtttcccg gaaaaaatct tacaattcca gcactaagtc tattgaattg
    10501 tgtttttgat ggttcgtgta tccacataac ctctccccaa tcaaattttt gtacttcatt
    10561 atttgactca ctaaaatact ccataagctc acctcttagt ttttgtctaa atattttttc
    10621 ttcccttctt atattaaaat aatatcatca tcattaactt tcattactat aaaatcatca
    10681 tactctttta atactcctgt aattttagtt gcacttagtt tactacaatt cagtttttta
    10741 atatattgat aaattctata attacttttt tattttgtaa aatcagtgtt ttcccaaaat
    10801 aattatatct ataaatgaaa gtatttttac tgcttacatc aatatatgtt atcataattt
    10861 tcctttttat tgcatatata aataactgta tataacattg tccaatacta tatagaaata
    10921 catctaagaa agaatattat taaattgttc caattagtat tatttttctt atagaaataa
    10981 aaaaactgtt ggagtctttt agaaaaatta ttttttacat accttttttg cttagatagt
    11041 ctatcttcac agctattttg tatatacact cttctagttc atgattttat tttaatatct
    11101 tgcttatatt gctgaaataa ttgaattctt ttatctatca tattgtctct tatatcacaa
    11161 acatattgtt tcttatatca caaaaatgaa agcattctta tatcttcaat atataaacct
    11221 gcttttttta atcttgtaat aaatatagga tactctatat tctcttccta gaaataacta
    11281 ataccactta tttttctatt atatagaaag taataaatct ttttcttaat aaaattcaat
    11341 agtaagtgga ataaaatttt atatgaataa gaacattata aaaatacttt atacaatagt
    11401 caataaaaga tattagcttc aaattatgtt aaagttgtat tatttaaagt gaaaaaacaa
    11461 ataaaaaaga aataatagta taagtagaaa aatatactta aaacaaggcg aagcctctct
    11521 tgtatctaaa tcaagtagag aattaaatct aaaaaagaaa ataaatataa aagatgactc
    11581 ctgtacatta caagaatcat cttatggttt cataatcact ccatggtttt taactgtctg
    11641 atataaaggt ctcagttcac tcatagcatg accacctttt ccgattgctg accccgtcac
    11701 ttatggacaa aatgtccata agtgatagtc ctctcttaaa accctctaaa tagatatatc
    11761 tcaagcaccg cattgaaacc agttgctgga aacaaactga agcgttctgg aatagtaaaa
    11821 gaaattgcca ccatatccac gttactgtcc tagttgttac tttgctaact tcggagcgat
    11881 ttcctctaac aatacgcagt caaattctgc ctttttgcta agaaatggca gatggtctgc
    11941 atctggtata aaaaaaatct gtttgtctgg cgccactatt tcatcaaaaa atttcttcgc
    12001 tggaagatag gggctattat agtcattttc tcccatgatg tagtatacag ggacctgata
    12061 gtcaactcca taatttctta tgtcagcttc ttccactaaa aaccgcaata catcaccttg
    12121 attgtcaatc gcatttggat tgaaaatggc cgtatttttt aactctctca atgaataata
    12181 cggggttgcc agtatactga ttatattgcc caaatccata tttatagaaa gcccatactt
    12241 gctttggtat gttcttactg tcataagagc tgccaaatag cttggaccat attttgctgg
    12301 cggatatggt gcaatagctt ccagcgcctt gatatctttt tgcttccctg cagctttcac
    12361 catttcaagt gtcttttcat agcccacgcg ctcattgtcc accatattaa cggtctgcgc
    12421 aatcccaatg tacgcgctgt aatcctccgg ataggtttgc acagccatag ttcccagaac
    12481 tgttccccag ctatgaccta taaggataat tttctccttg ttgaactctt gcttcaaata
    12541 tgctgtcacc tcatggacgt cttgcagaac acgctccgcg ctcatggtct gcaaaactgc
    12601 tgccggatcg ttcgcaaagt atgttttgcc tacgtttcgc tgatcccagt tcaccacagt
    12661 aaaatcattt tcccactcat actggtacag atgtaaaaat ggcatcattg aattaccagg
    12721 acccccatga acccaaagga tgatggggtt gtctgcgttt tgtccccgga tatataacgc
    12781 ctgctgtatg ccgccgatct ccaccatttc catgcggtcg attccaggag cttctatttt
    12841 atggcttgta cgtataatcg tgggggctat cagacgcaaa ccggcaaacg ccagaacaaa
    12901 aacagcaact agtatgcaaa gtgtgattaa tatcatttta agtaccttct ttcatgaatt
    12961 tttttagcca tagatatctc ctctaacatt aaaaaaaata tgttgctatt ttagttttgt
    13021 tactctacct gtcccattgg tttcctttca taaaaaatat taattgattc tataatctca
    13081 tcttccagga tatcaactcc tatttgtctc ataagaaact gtaagaattg aaaccgttta
    13141 cgaagtgtag gaaagtcccc ctgaaataca tctgtatcac accaaaagtt aaagagcagc
    13201 aaaattacct ctgcgcattc atctgggaac tctgtgatga tgcttctatc ctctatgcct
    13261 tctcgtaaaa catttgctaa tattggtgct agttttttca aattatcctg tgtaaatgcc
    13321 agtatgatat gcggactttc tatcgcgctt gtaatcatgt tactagattc ttttatcacc
    13381 tcatccgtta aatgccgcct aactaaactt ctaagcttct cttttgctgt aagtccatgc
    13441 atttcaccga gccattgatt tactgtctct attatctgtt caaagcgcct ttccatgacc
    13501 acattaaaaa tatcttcttt tgaactgaag tgatgaaaaa ttccgccctt tgacattcct
    13561 gaagcatcaa caatattttg catacttgtt ttgtcatatc ctttttcagc aaacaacttt
    13621 gcagaaatgg taatgatatt ttcaatagct tgctttggat tgttctttct agtcattata
    13681 taactccttc ttattaaaaa ccgactgttg gtttttatta tataagctat tcctgcttct
    13741 gtcaagtaac attgtgttta tggcaaaaca ataaggtttg gtggttagac aggtattaat
    13801 tagactaatg cgactttccc ctagatggaa cccttggtaa atttgcaatc tttaccggct
    13861 ttgattatat ctgtaagcaa ggcaggtatg gccacacctg ccctgtttgc ccctcggata
    13921 ttcattccta tccctcctct ccttagccat tacaccaaaa cgccgctcat tgtctccaat
    13981 ggcggcgttt taaagatatg atttctcatg ctgctgaaat atgcaaaaaa tataagatgc
    14041 cctttattat ttttcctaca atagaaaaga aaagtattga agaatgggtt aatattggag
    14101 caaatatgct ttgtttggca caagatacta cctttatcac ttatgttatc aatcaattat
    14161 tatcttttta taatgagatt gtaccaattc aaaaacaaca ttaaattata aatctaattt
    14221 tatattaaaa gagactaata ttttatctat ctctattaag gatattttct tatgtatcat
    14281 aatattagtc tctcttatta ttatatactg ctatcatcat tagttgctat ttatactatt
    14341 tttataatat acaaatttat tcagctaacg ttttgcctaa ttctatacac tcatcttttg
    14401 cttcttcatt tgggtcttcc attgctgtaa ttccttctcc accaataatt gtagcaccag
    14461 cattttgcat acgttcttcc caatctctca tccattcaca atttccccat ccatatgaac
    14521 caaataatcc aatctgttta cctgatacca tagattctaa ttctgaaaca aatggctcca
    14581 tatccccctc ttctagttgc tctgctccca tagatgggca acctaatgca aatttatctt
    14641 cttcttttaa atcacttggt ttcagtaagc tcacatctaa aacttctggt gtcttacctt
    14701 ttaacttcac accttcagcc acaaaatttg ccattttttc agtatttcct gttccactcc
    14761 aataaacaat atatatttta ctcattttta cctcctgtag tattttttaa ttaatcaata
    14821 gttagttata gctaactaac atctaaaaaa caaaagattt ctttatctga aatctcttta
    14881 tttttctaaa tatagaatat cacaattgat tttgaaattc aatacttatt gataacattt
    14941 atcatttata ctttatattc attttataat atcaaaacac tgtatcgtat ttctaatctt
    15001 tcatagaaaa atttctaact tatagtactt ttgcatctct tataaatctt ttatatgtat
    15061 aagtacatag aaaaacacac cttttccaga tgtgctatct ataatatcgt atatttattt
    15121 ttcaattcta actagctaat atgtttataa attttatcac ttaatacctt tatacattga
    15181 tgtaaaatct tacacctaag taatttttat tatttgtctc gactctatat aatatagcta
    15241 ttttatcatc aaatcaaaaa ttatcttttg ctattattct tgtatttata aagatttaaa
    15301 tataagtatc catttccttg ttccgttcta ggtattccaa gcgctctcgt acattttatt
    15361 aattgtgcat acagttcagc ttcatctaaa tctctttcaa actcctctct tgcccattct
    15421 ttaattagtg ctaatgagcc tgatacgtat ggtgcactca tactagtacc actcataata
    15481 gcaagtttat tatccatata agtcgatata atatttcttc ctggagccac caaatctatt
    15541 gtagtatttg aattactaaa cttttcaacc aaatagtttt catttattgc acctacttct
    15601 attacctcag cataactggc tggataacta tactcacttg tactagaatc accatctcca
    15661 ttattacctg ctgcacacac tacagaaata ttatttttta ctgcttgcat gacagcattt
    15721 tttaaattct tatcatcttt gtttccccca agagacatag atataatatc aaccttgtta
    15781 tttacagcaa agttaatagc attaattata ctttgatatg ttccggtacc atctttattt
    15841 aatgcttttg ctattaataa tttacaatct ggagctactc ccataacttc attattataa
    15901 ttagatgcag ctataatacc cgccacatga gttccatgac cattaaaatc ctcatatata
    15961 tttttatttc cattactgtc atcactaaaa tttgcaccac caattatttt tccttttaaa
    16021 agaggatgag atatatcaca acctgtatct attataccaa ctacaatatt tttaccagta
    16081 taaccttcat cccacattcc cctagcattc atttgtttta ttccatatgg gaatttattt
    16141 tttgcacctc ttagattttc atttatttca tatggaatta gtttcattct tttattcatc
    16201 atatatcctc ctaaaaattt tattgcttat aaaaatcatg aattttattt tataataggt
    16261 ttataaatca aattaaaacc tatatctact tatttatatt tatgatat
//
LOCUS       DAEPXW010000086        15979 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.087, whole genome shotgun sequence.
ACCESSION   DAEPXW010000086 DAEPXW010000000
VERSION     DAEPXW010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.087"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            248..397
                     /gene="rpmG"
                     /locus_tag="KRM55_002798"
     CDS             248..397
                     /gene="rpmG"
                     /locus_tag="KRM55_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBH1595015.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            423..644
                     /gene="secE"
                     /locus_tag="KRM55_002799"
     CDS             423..644
                     /gene="secE"
                     /locus_tag="KRM55_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBH1595016.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            664..1206
                     /gene="nusG"
                     /locus_tag="KRM55_002800"
     CDS             664..1206
                     /gene="nusG"
                     /locus_tag="KRM55_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBH1595017.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1245..1670
                     /gene="rplK"
                     /locus_tag="KRM55_002801"
     CDS             1245..1670
                     /gene="rplK"
                     /locus_tag="KRM55_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBH1595018.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1741..2439
                     /gene="rplA"
                     /locus_tag="KRM55_002802"
     CDS             1741..2439
                     /gene="rplA"
                     /locus_tag="KRM55_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBH1595019.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2491..2619
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2662..3168
                     /locus_tag="KRM55_002803"
     CDS             2662..3168
                     /locus_tag="KRM55_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBH1595020.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3226..3591
                     /gene="rplL"
                     /locus_tag="KRM55_002804"
     CDS             3226..3591
                     /gene="rplL"
                     /locus_tag="KRM55_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBH1595021.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3983..4771
                     /locus_tag="KRM55_002805"
     CDS             3983..4771
                     /locus_tag="KRM55_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH1595022.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5242..8958
                     /gene="rpoB"
                     /locus_tag="KRM55_002806"
     CDS             5242..8958
                     /gene="rpoB"
                     /locus_tag="KRM55_002806"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBH1595023.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9000..12485
                     /gene="rpoC"
                     /locus_tag="KRM55_002807"
     CDS             9000..12485
                     /gene="rpoC"
                     /locus_tag="KRM55_002807"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBH1595024.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12774..13196
                     /gene="rpsL"
                     /locus_tag="KRM55_002808"
     CDS             12774..13196
                     /gene="rpsL"
                     /locus_tag="KRM55_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBH1595025.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13320..13790
                     /gene="rpsG"
                     /locus_tag="KRM55_002809"
     CDS             13320..13790
                     /gene="rpsG"
                     /locus_tag="KRM55_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBH1595026.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13839..15905
                     /gene="fusA"
                     /locus_tag="KRM55_002810"
     CDS             13839..15905
                     /gene="fusA"
                     /locus_tag="KRM55_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH1595027.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6255 a         1989 c         3251 g         4484 t
ORIGIN      
        1 ctttactaaa ctgatggatt aaaaggaata acaaaaagag gggttatgct cctctttttt
       61 taacatagaa atacaaaaac attgacacag cataggattt tgtgataact tatacaaggt
      121 aatgattata ggaagttaat aatatcttga atactgtaga tttttaataa atacatattt
      181 taaagatatt atattcacat atattaacaa tatatattat tgtattacaa agttggaggt
      241 gtatcagatg agagttaaag taactttagc atgtacagag tgtaagcaaa gaaactacaa
      301 cactactaag aataagaaaa acaatccaga cagaatagaa ttacaaaaat attgtagatt
      361 ctgtaaaaag catacaactc ataaagaaac aaaatagttt tttataagga tgtgagtatg
      421 gaatggctgc ccaaaaaaat gacggtgcaa aaactaaaaa aaggtttagt ttgtttggat
      481 acttaaaaga aactaaacaa gaattaaaaa gagttacatg gccgacaaaa aaggaactgt
      541 ttaaaaacac aagtatagtt ttaactgtag ttatttcatg cactatatta gtatggggta
      601 tagacactat attatctggt gcactagcgt tattactaaa atagacgaaa agaggtaagt
      661 taaatgtcag aattacaaga agcaagttgg tatgtagttc atacctattc gggacatgaa
      721 aataaagtta aagctacaat tgagaaagca gttaaaacaa gaggtatgga agactgcata
      781 agacaagtag ttgttccaac agaagaagta gtggaaacta ctaaaactgg aaaagaaaaa
      841 actagacaac gtaaagttta tccaagttat gttttggtta aaatgataat aactgatgaa
      901 tcttggtatg tagtaagaaa tactaaggga gttacaggtt tcgttggacc tggttcaaaa
      961 ccagtgccat taagtgaaga cgaagtcaaa gctatgggga tagacacaac agaccctaaa
     1021 gtagtaaata gcgatattga ttttgaaata ggagatacag taaaagtatc tcaaggacca
     1081 tttagtggac aaataggtaa catagaagaa attgacttag aaaatagaga agtcaaagta
     1141 tgcataaatg catttggtaa aaggactcta tttgtaatag agcttgaagg tatagaaaaa
     1201 atctaatact atattataga aaaatctgag gaggtgcgct caaaatggct aaaaaagtta
     1261 taggtcaaat aaaattacaa atacctgcag gaaaggctac tccagcgcca ccagttggac
     1321 cagcattagg acaacatggt gttaatataa tgggattcac aaaagaattt aatgctaaaa
     1381 ctgcagatca agctggaatg ataataccag ttgttataac tgtatatcaa gatagatcat
     1441 tcagttttat aacaaaaact ccaccagctg cagttttaat taaaaaagca ttaaacttaa
     1501 aatcaggttc tggagaacca aacaagaaaa aagttgctaa aatgacttca gctcaagtaa
     1561 gagaaatagc tgaattaaag atgcctgact taaatgctgc atcagtagaa gctgctatga
     1621 gtatgatagc tggtactgct agaagcatgg gtgttgtaat cgaagactaa ttaaaagata
     1681 cacttttttt tataaagtgg gaggctagaa gccgaaatta accacgagga ggaaaataaa
     1741 atggctaaaa aaggtaaaag atatgcaggt gcattacaaa aagtagatag aactaaattt
     1801 tatgatgcat cagaagcatt aacattagtt tcagatatag ctggagctaa atttgatgag
     1861 acagtagaag cacacattaa attaggtgtt gactcaagac atgctgacca acaagtaaga
     1921 ggtgcagttg tattacctca tggaactggt aaaacaaaaa gagttttagt ttttgctaaa
     1981 ggtgaaaaag ctaaagaagc tgaacaagct ggtgctgact ttgtaggagc tgaagaatta
     2041 gttcaaaaaa tacaaggtga aaactggttt gactttgata tagtagttgc tactccagat
     2101 atgatgggtg tagtaggtag attaggtaga gtattaggac ctaaaggttt aatgccaaac
     2161 cctaaatcag gaacagttac atttgatgta gctaaagcta tagatgaaat aaaagctggt
     2221 aaagttgaat acagattaga caaaactaac ataatacacg ttccagtagg aaaagtatca
     2281 tttggtggag aaaaattaac tgaaaacttt actgcattaa tggatgctat aataaaagct
     2341 aaaccagctg ctgctaaagg acaatattta agaagtataa cagtagcttc ttcaatggga
     2401 cctggagtta aaataaaccc agcaagaaca gctgaataat aaaactgttg acacaggttg
     2461 acaaaaatgt tattatatca cttgtcaatg taaaaaagaa tagatttgcc gtagatagtg
     2521 ggtgcgagag cttaatatcc cgccgaggtt ttagataaat tgagattact aaagcttttg
     2581 atgtctactt ttggcaacaa aagcttttta taatgttgcg gtaaatacta agcctatttg
     2641 gtgaaggagg tgcacatcta tatgagaaaa gctatagaaa ttaaatcaga agttgtttct
     2701 gagatagttg aaaagttaca aaaatcttct gctgctgttg ttgtagatta caaaggatta
     2761 acagttgaag aagtaactga gttaagaaaa caaatgagag aagctggtgt agattacaaa
     2821 gtatacaaaa atactttagt tagaagagca gctaaagaag ttggtataga gcaatttaat
     2881 gatgaattat tagttggaac taatgccata gcatttggat atgatgatcc agttgctcca
     2941 gctagaatat taaaaggatt catggattct catccaaaaa tgaaattaaa gatgggtatt
     3001 gtggaaggtg cattctatga tgaatctaag attgttgaaa tggctaacat accatcaaga
     3061 gaagttctta tcgctaaatt acttggtagc ttaaaagctc cagtatcaaa cttcgcatac
     3121 ttaatagatg caatagcgaa aaaggcagaa ggtcaagaag aagcttaatt gcttaactaa
     3181 aaaattataa atattaattt gaaataaaat tcggaggtgc taaaaatgac aatagaacaa
     3241 atattagaag ctatagaaaa tatgaaagtt ttagaattaa atgaattagt taaagctgct
     3301 gaagaaaaat tcggtgtatc agcttcagct ccagtaatgg tagctggtgc agctgctggt
     3361 ggaccagctg ctgaagaaaa aactgagttt gatgtagtat taactgacgt tggttcttca
     3421 aaagttggag ttataaaagc agttagagaa ataacaggat taggattaaa agaagctaaa
     3481 gaagtagttg acaatgctcc taagacagtt aaagaaggag cttctaaaga agaagctgat
     3541 caaataaaag agaaattaga agctgctgga gctaaagtag aagttaagta gtttctttaa
     3601 aaagataccc attgggtatc tttttttatt tataaaaaac tataaagaaa gtatttggaa
     3661 ttataaagaa agtattttta taaaataaaa aaaatttata taatagtact aaattaaggg
     3721 tatcatatat ggtgtaatgg tattttaatt taacattatt atcaaattaa aatataaaca
     3781 attgttgtaa tgtctgtata taaagtatat aattaaacta aaatgtaaaa ttttacattt
     3841 tagtttaaaa aaatacacga gtgttttata aataaaatgt aataaataat taattaacaa
     3901 atataaattt taaaataagt tagatattta gaaaaatcga aatttgtagg atttaaagga
     3961 catattcaag gaggagttaa taatggaaaa attacaagga aaaattgcag tagttactgc
     4021 agcaacaaaa ggtattggat tagcatcagc agagatatta gcaaaaaatg gagcaactgt
     4081 gtacttagca gctcgttcag aagaattagc taatgaagtt ataaataaaa taagtgcaga
     4141 aggtggttgt gctaagtttg tttactttaa tgctcgtgag gaagagacct ttacctcaat
     4201 gatagaagag gtagttaaaa aagaaggtaa gatagatata cttgtaaaca attttggttc
     4261 aacaaaccct tctcttgaca aagaccttgt aactggagat acagataatt tctttgacac
     4321 agtaaatact aatttaaaaa gtgtgtattt accatgtaaa gcagcaattc ctcatatgat
     4381 aaagaatgga aaaggaagta tagtaaatat atcaagtata ggttcagtat tacctgattt
     4441 atctagaata gcttactgtg tatcaaaagc agcaatcaac tcattaactc aaaacatagc
     4501 tacacaatat gctaaagaca atgttagatg taatgctgta cttccagggc ttattgcaac
     4561 taaagcagca ttagacaata tgtctccaga gttcataaaa gaatttttaa agcatgttcc
     4621 tttaaatcgt ataggggaac cagatgatat agcaaaagct gttctattct atgctagtga
     4681 tgactcatca tttataacag gggatttact tgaagttgca ggaggatttg gtttacctac
     4741 tccacaattt gcagataata tattaggata attaaattac taatatgcaa tgaaagctta
     4801 tgcattagtt atagtagaaa tgatattttt ataaaggcca tagatataat ttatattgga
     4861 aaggtttgag gttcaaaatt ccaagttaaa tttatttatg gtctttattt tgtatatttt
     4921 aataaattgt atatatttgt ataaatgtaa ttatttacaa tcattttaat atggaattat
     4981 aattaaatag gggggatggt acttgtataa aattttttat agaaaattag acctataaat
     5041 gaaaaatatg gattttatat tggaaaattg tacataatac ataatatatg cttaaaataa
     5101 tttacaaaaa atcaaaaata atgcatagtt tacatataag ataaaaaata tattgaaaaa
     5161 tacttgacat tatgctaaaa ttattagatg cgttagaatg aactattgtt ttatttttaa
     5221 ttattgagag gtgaaaagtg aatgccacat cctgtcacga taggtaaaag aactagaatg
     5281 agcttttcta aaattaagga aatagctgat gtgccaaatc ttatagaaat tcaagtagat
     5341 tcctatgagt ggtttttaaa agaaggttta aaagaagtgt ttgatgatat ttcaccaata
     5401 gaagattata ctggtaatct tatattggaa tttgtcgact attctctaga tgataaacca
     5461 aagtacgata tagaagagtg taaagagaga gatgctacat attgtgcacc tctaaaggtt
     5521 aaggtaagac ttataaataa agaaacaggt gagataaaag aacaagaagt gtttatgggt
     5581 gacttccctt taatgacaga aagaggaact ttcgttataa atggagcaga aagagttata
     5641 gtaagtcaat tagttagatc tcctggtgtt tactatgcgg aagaaagaga taaaacaggt
     5701 aagagattga tttcatctac tgtaattcct aatagaggag catggttaga atatgaaaca
     5761 gattctaatg atgtaatatc tgtaagagtt gatagaacaa gaaaacaacc agttacagtt
     5821 ttacttagag ctttaggaat aggaacagat gcagagataa ttgacctttt aggagaagat
     5881 gagagattat ctgctacatt agaaaaagat aatactaaga cagtagaaga aggtcttgta
     5941 gagatataca aaaaattaag accaggtgaa cctcctactg tagaaagtgc atcatcttta
     6001 ttaaatgctt tattctttga cccaaaaaga tatgacctag caaaagttgg tagatataaa
     6061 ttcaataaga aacttgcttt atgttataga ataatgaata aaatttcagc agaagacata
     6121 ataaatccag aaactggaga agtatttgta aaagctggag aaaaaataag ctatgatttg
     6181 gctaaagcca tacaaaatgc aggtataaat gtagtaaatc tactaatgga tgatgataaa
     6241 aaagttagag ttataggaaa taattttgtg gatattaagt ctcacattga ttttgacata
     6301 gatgatttaa acataaaaga aaaagtacat tatccaactt taaaagaaat tttagatgga
     6361 tatagtgatg aagaagaaat aaaagaggct ataaaatcaa gaattaaaga acttatacca
     6421 aaacatatat tattagatga tataatagct tcaataagtt atgagttcaa tatattctat
     6481 aatataggaa atattgatga tatagatcac ctaggaaaca gaagaataag atctgtaggt
     6541 gaattgttac aaaatcaagt tagaattggt ctttcaagaa tggaaagagt tataaaagaa
     6601 agaatgacgg ttcaagatat ggaagctata acgcctcaag cgttagttaa cataagacca
     6661 gtttcagctg caataaaaga attttttggt agttctcagt tatctcagtt catggatcaa
     6721 acaaatcctc tatctgagtt aacgcataag agaagattat cagcccttgg gcctggaggt
     6781 ctttcaagag aaagagctgg attcgaagtg cgtgacgttc accattcaca ctatggtaga
     6841 atgtgtccaa tagagactcc agagggacca aatatcggtc ttataaactc tctaggaact
     6901 tatgcaaaaa taaatgaatt tggatttata gaatcaccat atagaaaatt tgataaagaa
     6961 acatcaacag ttactgatga aatacattat ttaactgctg acgaagaaga tttattcgta
     7021 agagctcagg caaatgagcc attaacagaa gatggtaaat tcgtaaacca tagagttgtt
     7081 tgtagaactg taaatggtgc tgttgaaatg gttcctgaaa gtagagtaga ttacatggat
     7141 atatctccta agcaggttgt atctgttgcc actgctatga tacctttctt agaaaatgat
     7201 gatgccaacc gtgcccttat gggagcgaac atgcagcgtc aggcagtgcc tctagttaga
     7261 agagaagcac caattatagg aactggtata gaatacagag cagcaaaaga ctctggagca
     7321 gttgttgttg ctagaaattc tggtatagca gaaagagtaa cagcagatga aataattata
     7381 aaaagagaag atggaaacag agatagatat aatctactta agtttaaacg ttcaaactca
     7441 ggtacttgta taaatcaaac acctataata aataagggtg accagataat aaaaggtgat
     7501 gttatagcag atggtccagc aactgattta ggagaagttg cacttggaag aaactgtctt
     7561 atagcattca tgacttggga aggttataac tacgaggatg ctatattaat aaatgaaaga
     7621 ttagttaaag aagatagatt atcaacaatt catatagaag aatatgaatg tgaagctaga
     7681 gatacaaaac tagggccaga ggaaataact agagatatac ctaatgttgg agatagtgca
     7741 attaagaact tagatgacag aggtataata agaataggtg cagaagtaga ctcaggtgat
     7801 atattagttg gtaaagtaac tccaaaagga gaaactgaac ttactgctga ggaaagatta
     7861 cttcgtgcaa tatttggaga aaaggctaga gaagttagag atacttcact taaagtgcct
     7921 catggtgaat ctggtataat agttgatgta aaagtattta ctagagaaaa tggagatgat
     7981 ttatctccag gagtaaatga attagtaaga tgctatatag ctaaaaagag aaaaataaaa
     8041 gttggagata aaatggctgg tcgtcatggt aataaagggg ttatctcaag agtattacct
     8101 gaagaagata tgccattcat ggaaaatgga acaccactag acataatact taacccacaa
     8161 ggtataccat cacgtatgaa cattggtcag gttttagaag ttcatttagg acttgctgct
     8221 aagacattag gatggtatgt agcaacatca gtattcgatg gtgctaatga gtatgacata
     8281 atggatgctc ttgaagaagc tgggtatcct agagatggta aattaacttt atatgatggt
     8341 agaacaggtg agtcttttga caacagaata actgttggat atatgtacta cttgaaacta
     8401 catcacttag tagatgaaaa actacatgca agaagtactg gaccatactc attagttact
     8461 caacagccac taggtggtaa agcacaattt ggtggacaaa gatttggaga gatggaggtt
     8521 tgggctctgg aagcatatgg agctgctcac atacttcaag aaatacttac tgttaagtct
     8581 gatgacgttg taggtcgtgt tagaacatat gaagctatag ttaaaggtga aaatatacct
     8641 gaaccaggaa tcccagaatc atttaaggtt cttataaaag aacttcaaag tttatgctta
     8701 gatgtaaaag tattgacaga tgaagaccaa gaaatagaag taagagaatc tgtggatgaa
     8761 gatgatacaa taggtgaatt tgagctagat gttgtaaatc atatgggaga agttgaagaa
     8821 agtaatataa tagaagaaat tgaagatgat tttgcagaaa atgcagaaga tgaggatata
     8881 gagaatttag aagaattcac tgaagatgat ttatttgaag aagaaataga ttttgatagt
     8941 gatgactttg atatgtaaat ttaattaatg taaatctcaa atagaaggga gagaactcct
     9001 tgtttgaatt aaacaatttc gagtcgataa aaatagcatt ggcttctcca gaaaaaataa
     9061 gacaatggtc taggggagaa gttaaaaagc cagaaactat aaattaccgt actttaaaac
     9121 cagaaaaaga tggtcttttc tgtgaaagaa tatttggacc acaaaaagac tgggagtgcc
     9181 actgtggtaa atatagaaga gttagatata aaggtgtagt ttgtgataga tgtggagtag
     9241 aagtaactaa atcaaaagta agaagagaga gaatgggaca tatagagcta gctgctccta
     9301 tgtctcacat ctggtacttc aaaggtatac caagtagaat gggactttta cttgatatgt
     9361 caccaagatc gttagaaaaa atattatact ttgcctcata tgtggtagtt gatccaggag
     9421 agactggatt aaacgaaaaa caattgctta cagaaaaaga atacagaact gctcttgaaa
     9481 agtatggata tacttttact gtaggaatgg gtgctgaagc tgtaaagaca ttactacaaa
     9541 atatagattt agagcaacaa agtaaagacc taagagcgga gttaaaagat agtacagggc
     9601 aaaagaaagt tagaacaata agaagattag aagttgtaga ggcatttaaa aagtctggaa
     9661 ataaaccaga atggatgatt ttagatgcaa taccagtaat accaccagat ttaagaccaa
     9721 tggtacaact tgatggtgga agatttgcga cttcagacct aaatgattta tatagaagag
     9781 ttataaatag aaacaataga cttaaaagat tattagagct tggagctcca gatataattg
     9841 taagaaatga aaaaagaatg cttcaagaag ctgttgatgc attgatagat aatggtagaa
     9901 gaggtagacc tgtaacagga cctggaaata gaccacttaa atctttatca gatatgttaa
     9961 aaggtaagca aggtcgtttc cgtcaaaact tacttggtaa gcgtgttgac tactcaggac
    10021 gttctgttat agttgttgga ccagaactta aattttatca atgtggactt ccaaagaaga
    10081 tggcattaga attattcaag ccatttgtta tggataaatt agttaaagaa ggttatgcac
    10141 ataatataaa aagtgcgaaa tctatagtag aaaaagttaa gccagaagtt tgggatgttt
    10201 tagaagatgt tataaaaagt catccagttc ttcttaaccg tgcaccgact ctacatagat
    10261 taggtataca agcatttgaa ccaatcttag ttgaaggtaa ggctataaaa ctacatcctc
    10321 ttgtatgtac agcttataat gcagactttg atggtgacca aatggcagtt catgtacctt
    10381 tatcagtaga agcacaagca gaagcaagat tcttaatgct ttctgtaaat aatatacttg
    10441 ctcctaaaga tggttcacct ataactactc catctcagga tatggtttta ggttgctatt
    10501 atctaacaat agaagcccaa gatggagcta aaggaacagg tatggtattt aaagacttta
    10561 atgaactatt acttgcttat tacaataaat cagttcatct acatgcatta gtgaaactta
    10621 aggtaacact tgaagatgga agaagttcat tggttgaaag tactgttggt agatttatat
    10681 ttaatgaaaa tatacctcaa gacttaggtt ttgtagatag aaaagaaaat ccatttgcac
    10741 ttgaagttga tttcttagca gataaaaaat ctcttggtaa aataatagat aaatgcttta
    10801 gaaaacacgg aaatacagaa acagctgaat tactagatta tataaaagct ctaggattta
    10861 aatattctac attaggtggc ataacagttg ctgttgatga tatgagtgtc ccagaagaaa
    10921 agaaagtatt tatagctgag gcagaagcta aagttgataa gtatgaaaaa gcatacagaa
    10981 gaggtctaat ctctgatgaa gaaagatatg aaaaagttat agagacatgg acagaaacaa
    11041 ctgataaagt tactgatgct cttatgggtg gactagatag attaaataat atatatataa
    11101 tggcacattc aggagccaga ggttctaaaa accaaattag acagctggca ggtatgcgtg
    11161 gtcttatggc aaatgcatct ggtaaaacag ttgagatacc agttaaatct aatttccgtg
    11221 aaggtttatc agtactagaa tactttacat cttcacatgg tgccagaaaa ggtcttgccg
    11281 atacagctat acgtacagct gaatctggat atttaacaag aagacttgtt gatgtaagtc
    11341 aagatgttat tgtaagggaa atagattgtg gaacagaaga tactacagag atttatgcta
    11401 taaaagaagg aaatgaagtt atagaagaga tatatgatag aattgtagga agatatacta
    11461 tagaccctat attaaatcct gaaactggag aagttatagt tgaggctgat tcaatgatac
    11521 aagaagatga agcagaaact atagtagctt taggaattga aaaaattagg ataagaacag
    11581 ttcttaactg taaaactaat catggagttt gttctaagtg ttatggtaga aacttggcaa
    11641 caggaaaaga agttaatata ggtgaagcag ttggtataat agcagctcaa tctatcggtg
    11701 agccgggtac tcagcttaca atgcgtacat tccatactgg aggagttgca ggagctgata
    11761 taactcaagg tctaccaagg gttgaagaat tatttgaagc tagaaaacca aaaggattag
    11821 ctgtaataac tgaagtatct ggtagagttg aaattgatga aacaggaaag agaaaagaag
    11881 taaatgtaat accagaagaa ggcgagactc aaacatatgt aattccatat ggttctagat
    11941 taaaagttaa gcaaggtcaa atgctagagg ctggagaccc tctaacacaa ggatttataa
    12001 atcctcatga tatagtaaga gtaaatggtg ttaagggagt tcaagaatat atagttaaag
    12061 aagttcaaag agtgtataga cttcaagggg ttgatgttaa tgataagcat atagaagtta
    12121 tagtaagaca aatgctatct aaagtaaaag ttgaagaccc aggagataca gatttattgc
    12181 caggtggata tgaagatgta ttaacattca atgaatgtaa taaagatgct atagataaag
    12241 gtctaagacc agcagttgct aaaagagttt tacttggtat aactaaagca tctcttgcaa
    12301 ctgattcatt cttatcagca gcttctttcc aagaaacaac aagagtatta acagaggcag
    12361 caataaaagg taaagaagac cacttaatag gacttaaaga aaatgttata ttaggtaagt
    12421 taataccagc aggaacagga atgaagaaat atagaaatat agctgttgaa aaaattgaag
    12481 attaatagca tatagagtaa agaaatcttg acaaccatta tttgtggtgt taaaatagta
    12541 aagtgtgttg tttaaaagta cactaagggc ttgaacaagt tcttagtgac ttttagatgg
    12601 caataaatga gaactaaaaa gcatcaagct agaaaagtgc taatatcaca tatttatgtg
    12661 ttatagacat taaattgtaa gtaacgaatg ttacaatcag tcagtatgaa tattcatatt
    12721 gatgtagttg gcggtcactg ataagatcga aaatttggaa ggaggtgcag atgatgccaa
    12781 caattaacca attagttcgt aaaagtagaa aagcgctaga gaagaaatct actgctccag
    12841 cattacaaaa aggttacaac tctttaaata agaaagtaac tgacgctagt gccccacaaa
    12901 aaagaggggt ttgtacttca gtaaaaacag ttactcctaa gaagcctaac tcagctttaa
    12961 gaaaagttgc cagagttaga ttaactaatg gtatagaagt ttctgcttat ataccaggag
    13021 aaggacacaa cttacaagag catagtgttg ttcttataag aggaggaaga gtaaaagacc
    13081 ttccaggggt tagataccat atactaagag gtactctaga tacagcaggt gttgataaga
    13141 gaagacaatc aagatctaaa tacggtgcga agagacctaa agaagctaaa aagtaaaaac
    13201 aattaatgat tgattatagt tcggtgcttt aaatatatat atatttacgg catcacggca
    13261 ttaaatgatt tatgtcgagt acctatgatt taagttaaat aattaaggag ggaagcgaaa
    13321 tgccaagaaa aggtaatatt ccaaaaagag aagttttacc agatcctatg tatgggagta
    13381 aggtagttac taaattaata aataatctaa tggtagacgg aaaaaaagga aagtctcaaa
    13441 gaatagttta tgatgctttc gcaattgttg ctgaaaagac aggagaagaa gctttagaag
    13501 tatttaataa agcaatggat aatataatgc ctgttttaga agtaaaagca agaagagttg
    13561 gtggggcaaa ctaccaagtg ccaatcgaag ttagacctga aagaagacaa acattaggtt
    13621 taagatggct agtaaaatat actagagctc gtggagaaaa aggaatggtt gaaaagctag
    13681 ctaaagagat aatggacgca gctaacaaca ctggagcttc agttaagaaa aaagaagata
    13741 ctcataaaat ggcagaagct aataaagcat ttgctcatta cagatggtag gatatataga
    13801 tatcttataa aattgaggat atcataagga ggataaccat ggctagaaag tttcctttgg
    13861 aaagaactag gaatatagga atcatggctc atatagatgc aggaaaaact actactacag
    13921 aaagaatcct gttttatact gggcaaactc ataaaatagg agaaactcat gaaggagctt
    13981 ctcaaatgga ctggatggag caagaaaagg aaagaggtat aacaataact tctgccgcta
    14041 ctactgcttc atggaaagac catagaataa acataataga tactcctgga cacgtggact
    14101 tcacagttga ggttgaaaga tctctaagag ttcttgacgg ttcagttgct gtattctgtg
    14161 caaaaggtgg ggttgagcct caatcagaaa atgtatggag acaagctgaa acttatggag
    14221 tacctagaat agcttttgta aataaaatgg atatattagg tgcagatttc tacaatgttg
    14281 taagcatgat gaaatctaga ttaaattcta atgcagttcc tatgcaatta ccaataggta
    14341 aagaagattc atttataggt ataatagact tattaaaaat ggatgctgtt atatacaaag
    14401 acgacctagg ggttgaaatg gaagaaacag atataccaga agatatgaaa gaattagctg
    14461 ctgagtggag agaaaaatta gttgaatcag tagctgaaac tgatgaagaa ttaatgatga
    14521 aataccttga aggtgaagaa cttactatag atgaattaaa agttgctata agaaaagcta
    14581 ctatagcttg tgaaatgaac ccagttttct gtggtacagc ttatagaaac aaaggtgttc
    14641 agttagtaat agatgcagtt ttagattact taccagcgcc aactgatata ccagctataa
    14701 aaggtatatt agcagatgga gaagaagctg aaagacattc ttctgatgaa gagccattct
    14761 ctgcattagc attcaaaata atgactgacc cattcgttgg aaaactagcg ttcttcagag
    14821 tttattctgg aacattagaa tcaggttctt atgttttaaa tgcaactaag aataagagag
    14881 aaagaattgg tcgtatatta caaatgcatg ctaatacaag agaagaaata actaaagtgt
    14941 atgctggaga tatagcagca gcagtaggat taaaagatac tactactgga gacacattat
    15001 gtgaccctgc taatccaata atacttgaat ctatggaatt ccctgagcca gttatatctg
    15061 ttgctataga accaagttct aaagcagctc aagaaaaaat gggtatagct cttcaaaaat
    15121 tagctgaaga agacccaact ttcacagtta agactgacca agaaacagga caaactataa
    15181 tatctggtat gggtgaatta cacttagaga taatagtaga tagattatta agagaattta
    15241 aagtagaagc taaagttggt gcaccacaag ttgcatatag agagactata actcaaccag
    15301 ttgatgttga atacaagtac tctaagcaat caggtggtag aggacaatac ggtcacgtta
    15361 agattagagt tgctcctcaa gagccaggtg aaggatacaa attcacaaac aaaactgttg
    15421 gtggatcagt accaaaagaa tatgttggtc cagttgacat gggtatacaa ggagctatgc
    15481 aatctggtat agttgctgga tatccagttg tagacgttgc tgttgagtta tatgatggtt
    15541 cttaccatga ggttgactct tctgagatgg cgtttaagat ggctggttca atggcattca
    15601 aagatgctat gaagaaaggt aatgcagttc ttttagagcc ttacttcaaa gtagaagttg
    15661 ttactccaga agattacatg ggagatgtta tgggtgactt aaactcaaga agaggattaa
    15721 tccaaggtat ggaagctaga agtggtgcac aagttataaa tgcattcgtt ccactttcag
    15781 aaatgtttgg atactcaaca gacctaagat cttcaactca aggtcgtgca acttacacaa
    15841 tgatattcga tcactatgag caagttccag cttcagttgc taagaaaata gctgaaggaa
    15901 aataatttaa aaataattaa taatataaat ataaaaaata atcagctaga tgagagatat
    15961 ctctcatcta gcacaagat
//
LOCUS       DAEPXW010000087        15877 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.088, whole genome shotgun sequence.
ACCESSION   DAEPXW010000087 DAEPXW010000000
VERSION     DAEPXW010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15877
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.088"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            150..1055
                     /locus_tag="KRM55_002811"
     CDS             150..1055
                     /locus_tag="KRM55_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH1595028.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKNVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            1179..2132
                     /gene="msrA"
                     /locus_tag="KRM55_002812"
     CDS             1179..2132
                     /gene="msrA"
                     /locus_tag="KRM55_002812"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBH1595029.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            2285..3415
                     /locus_tag="KRM55_002813"
     CDS             2285..3415
                     /locus_tag="KRM55_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595030.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(3532..4500)
                     /locus_tag="KRM55_002814"
     CDS             complement(3532..4500)
                     /locus_tag="KRM55_002814"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBH1595031.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            4835..5023
                     /locus_tag="KRM55_002815"
     CDS             4835..5023
                     /locus_tag="KRM55_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595032.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTCFKNII
                     EVMYISKSLIMDEISKRD"
     gene            5283..6482
                     /locus_tag="KRM55_002816"
     CDS             5283..6482
                     /locus_tag="KRM55_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBH1595033.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAINLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            6534..7037
                     /locus_tag="KRM55_002817"
     CDS             6534..7037
                     /locus_tag="KRM55_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595034.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            7144..7461
                     /locus_tag="KRM55_002818"
     CDS             7144..7461
                     /locus_tag="KRM55_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595035.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            7619..8578
                     /locus_tag="KRM55_002819"
     CDS             7619..8578
                     /locus_tag="KRM55_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH1595036.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            8693..9478
                     /locus_tag="KRM55_002820"
     CDS             8693..9478
                     /locus_tag="KRM55_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595037.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            9770..11089
                     /locus_tag="KRM55_002821"
     CDS             9770..11089
                     /locus_tag="KRM55_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1595038.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(11164..11592)
                     /locus_tag="KRM55_002822"
     CDS             complement(11164..11592)
                     /locus_tag="KRM55_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595039.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(11683..13059)
                     /gene="hydG"
                     /locus_tag="KRM55_002823"
     CDS             complement(11683..13059)
                     /gene="hydG"
                     /locus_tag="KRM55_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBH1595040.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(13060..14145)
                     /gene="hydE"
                     /locus_tag="KRM55_002824"
     CDS             complement(13060..14145)
                     /gene="hydE"
                     /locus_tag="KRM55_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBH1595041.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(14181..15389)
                     /gene="hydF"
                     /locus_tag="KRM55_002825"
     CDS             complement(14181..15389)
                     /gene="hydF"
                     /locus_tag="KRM55_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBH1595042.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(15404..15655)
                     /locus_tag="KRM55_002826"
     CDS             complement(15404..15655)
                     /locus_tag="KRM55_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBH1595043.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
BASE COUNT         5977 a         1860 c         2504 g         5536 t
ORIGIN      
        1 tttattttaa gtattaaagg tttgaatgta acttaaatat taaaagagga acattgtaat
       61 atgtaacttg cataaaatat atatactata gtgaaattat tttgattaaa atttaaaata
      121 taaggtgttt tatgtggggg tatatgtata tgaaaaattc taattttaat atattggcat
      181 ttgatggtgg tggattaaaa ggggcattga gtatatccat acttgagagg atagtaaaag
      241 agtatccaaa tctattaaac aatataaata tgtttggagg tacatctaca gggagtctaa
      301 ttgcactagg gcttgcgtat ggtgtaagcc ctaaagagat aaaagaactt tactcaattg
      361 aaaattcaaa gtatattttt aataaaagtt atgcagaaat actcagacca aagtatgaaa
      421 acaaaaactt aaaagaagtt ttattaagta tatttccaga ggaactagaa ttaaaagatt
      481 taaataaatt agtaatgata ccaagttttt atataggaaa tgaggaaaat gcatggaaac
      541 cagtgtttta taacaatatg ccaaattctt ttacaaagac tagcaaagtt gtagatgtag
      601 caatggcaag tagtgctgct ccggtatttt ttccaacata taatcgtcat gttgatggag
      661 gaataatagc aactgacccg agtttagcgt gtataattca tgccattgac agtggattta
      721 aacttaaaaa tacaagactt ttttcaatag ggactggata tgtatataac agtataaagg
      781 cagatactac tgaatgggga gctattgact ggataattaa taaagaaccc gatttaccaa
      841 ttatatctat taccttagaa ggaaattctc aaatgagtca gttattttct caaaaacttc
      901 ttggagataa ttactataga ttaaatccta agatggaaaa aaatgtagct atggatgatt
      961 gtgatgcatt agaatatcta atgtctttag gagaaaattg tgatataaaa gatgcttttg
     1021 gatggataaa gaaaaagagc ttttatagaa attagattca atttgcaatt gtatttttac
     1081 acatgatttc attgagtagg taaaaataat aaaatgcaga ttattaagtt acttcttagg
     1141 gaataaataa agtataattt atttaaggag tgatgaaaat gataaaactt gctacttttg
     1201 caggtggatg tttttggtgt atggtaaaac cttttgataa gtatgatgga gttattaaag
     1261 tagtttctgg atatacaggt ggtcatgttg aaaaccctac atatcaagag gtatgttcag
     1321 gaactactgg tcatttagaa gcaattcaaa taacatatga tgatgatata ataagttatg
     1381 atgaacttct aaatatcttc tggaaacaga ttaatcctac agatgatggt ggacaatttg
     1441 gtgatagggg aactcaatat aagactgcta tattttatca tgatgaagaa caaaaaaata
     1501 tagctttaga gtcaagagaa catctggaaa atagtaaaat atttgatagt aaaatagtga
     1561 ctgatataat tccagcaact aaattctacg aagcagaaga aaatcatcag gattattata
     1621 agaaaagacc attaaactac aatatgtatt ataaagggtc cggaagatat aattttgtaa
     1681 aaagtcattg ggatggaaac aatataaata gggaagagtt aaaaaagact ttaactccta
     1741 tacaatttga agttactcaa aatgatatga cagaagtacc ttttgaaaat gaatattatg
     1801 acaataacaa agagggaatt tatgttgata ttgtaagtgg agaagtgtta ttttcttcaa
     1861 aagataaatt tgattctgga tgtgggtggc caagtttttc aaagccagtt atagataaat
     1921 ctatcattga gagaagtgat ttctcacaag gtatgtacag agttgaagta agaagtgcta
     1981 aaggaaattc tcatttaggt catgtatttg atgatggtcc aaaagaactt ggaggtttaa
     2041 gatattgtat aaattctgct tctcttaaat ttataccaag agaaaatatg gaagctttag
     2101 gatatggaga atatttaaaa ctttttgagt aattaggaat atttattata aacttatcta
     2161 aaaggtgaaa atctaaaaaa atattttcac cttttgtttt tttgtcaata gtatgataaa
     2221 ttattaattg taatcttatt tataccaata gattaagaat ttaattttga aagagagaaa
     2281 acaaatgaat ttaaaagact ttaatggaaa gagattaaaa tcagctagaa tttttagagc
     2341 aaagacgata gaacagttgt ctaaagaaac taaaataaat aaaaaagatt taaaagcttt
     2401 tgaggaaaat aagtatgtac caaatataga aaatacatta aaattatcta atatattaaa
     2461 ttttccaaaa gagtattttt ataaaaatga aaatataaat atcgttgtag aggatagcca
     2521 ctttaaccct caatctaaac tacctagagt agaagagatt tcttatagag aaaaaataat
     2581 tataatacat aaaatatatt catttatgga gaattatatt aagtttccaa aagaaaactt
     2641 gccaaataga aaagtaatgt cagatattaa tataaatgat atagaatctc ttgcatataa
     2701 gactagagag ttttgggatt taaatagtac tccaatagta aatatggtaa gtttgttaga
     2761 gtctaaaggg attataatat caggtatgaa tgtagataga aaaggggcaa ctatctttac
     2821 tcaaaaacag agaattagta aagaatctaa atatctaata tctctgggta atgacaaaaa
     2881 gtcagcatca attagaaatt atactttggc atgtgagctt ggatatataa tatcaagtga
     2941 attaagaata ccaagtaagc aattttcaga agatgagtat gcctgtgcat ttttattgcc
     3001 aaaagagagt tttttaaaag atttgactca tccagaagat ttagattatt atgtagaact
     3061 aaagaaaaaa tggattgtac ctatatctgc tatgattttt agagcatata atctagaaaa
     3121 gataaattac aaaaaataca attatcttat gaatgaaatg gataaaaaag gctggttgat
     3181 agaagaacca ctagacaaaa tgaaaggttc aagcccaacg tatttaaaaa gagcagttga
     3241 attattgata gaaaataaaa taatgagtgt aaatagtata gtatcaagtt tagaggaatt
     3301 tggaataaat ctttatccag aagacttaga attattgatg ggattgaaaa aaggattgtt
     3361 atctcaagag gtaaataaaa aaagtaaagt tataaaattt gatggtaaaa aataggttta
     3421 tattttagta ttaaaattaa aagcaggtac aaatgattta aacattaact tagttaaaag
     3481 ttttttcaat aagtcattta cctgctttta gtgtaagaaa gaatattgaa tctaaagtgt
     3541 ttttgaaagt gcaatatatt cccttaaaac agaacaagat ttattaaatt cgttttgctc
     3601 atattcagtc atattgattt caataatttc ttcaatacca tcttttccta taacacatgg
     3661 aacacctgca aatacatttc tttcgttata ttgaccttct agtaatgtag aaactggaag
     3721 aacttttttc tcattgtgta gtatagcttt tacaatttct actaaagcag tacctatacc
     3781 aaattctgta caatctttac catttattat acttattcct gtttttttat ttttttcaac
     3841 tattgatggt aagtctaaat tgctataagt acttgggttg tcttttatca tgtctaagat
     3901 tggtttacca ccaattgaaa catgagacca aggaaccatt tgagaatctc catgttcacc
     3961 catagaataa gcttgaattg attgttgagc gattccagtt tcttcagata aaatccttct
     4021 aagtcttgtt gaatctaaag ctgttccagt tccaatgact ttgtttttag gaaagccaga
     4081 tttttcccaa atataatttg taactacatc aacaggatta gatatgacta caaatatacc
     4141 atcaaagcca gaatcaacta tgggttttac tatagatttt atcattccaa tagttggtct
     4201 tagtaaatct aatctagttg tgttttgtct acgtaaaggc ccttctgaag agtctgcaac
     4261 acttatcact actatgtcag aatctttaca gtcagaaaaa gttccttttt ctatatgtac
     4321 tttatgtggc agatatgaaa ctgcatcagc taaatctaaa gcttgagctt ttgatttaga
     4381 ttcatctata tcaatcataa agagttcatc acaaactcct tgagttatta aactaaatcc
     4441 acaatgagaa ccaacatgcc ctgaacctac aatagatatt tttcttggct ttattgccat
     4501 tttaaatcac tccccctaaa ataacgatac attgaaaatt atagatgtta ttaaaagctg
     4561 tttttgaata ttttaatatt ctattatttc agaaaattta tttaatatga ttttatacta
     4621 aaatttttaa aaaagcaatg ttaatatact ctctattagt gaatattaaa gtattatatg
     4681 tatattaata attattaaaa tatgtaatgt cactgatagt tagaatattt aagtgctaaa
     4741 agatgtgtat aaataataat gatgtcagct tataatgata ttaaattgag atatactgtt
     4801 tctctaaatt aaaaaataaa ggagtaaatg tgttatgaat tatcatacaa aagaagaatt
     4861 ggtggaagca ctgagagtag tatcttcaag tattattaat tgtggaaaag gacagaagaa
     4921 attttctgag gagacatctc atcatacatg ttttaagaat attatagaag taatgtatat
     4981 ttcaaaatca ttaataatgg atgaaattag taaaagagat tgaagcttat tttgcaattt
     5041 aacatgtttt aatatacatt ttattatata agaaaataag taaacataca tgttataaaa
     5101 tattggaata atatacaatt ataaatttgt taacactaat atctatatgt taaaatatag
     5161 tagaagatgt tagtaaataa taggatgagt tctattttaa tacaattaaa ttaagcttag
     5221 tttgaaattt gtatctaaaa agtaaagtaa tctagaatta agaaaatgga gatagaatta
     5281 taatggaaaa attatactat acaaatcagt atataagaga ttttacagca gaaataattg
     5341 aaataaaaga agtagaaaat aagtatcatg ttttattaga taagacagct ttttttcctg
     5401 gtggaggagg tcagtttgga gacctgggaa aaatagagaa tgatgatgta ataaatgtgt
     5461 atgaagatgg aaaaaaaata taccatgtat tagataaaaa acctataaag atacataagg
     5521 taaagtgtag tattgattgg gatagaagag aagatggaat gcatcaacat tttggacaac
     5581 atgtattgtc tggatgtttt tttaaaactt ttaatgcaaa tacgacaggt tttcatttgg
     5641 gaaatgagta tagtacagta gatatagaag gtaatttaga agaggataaa attagagaga
     5701 tagagttgtt tgccaatgaa attattcgtc aaaatataca agtagagaca ttacttccaa
     5761 cgaaaaaaga actaaaaaag atttggttaa gacgtgattt gccaaatact gatgaagaga
     5821 taagagtaat aaaaataggt gatttagata cgaatgcatg ttgtggagtg catccaaaat
     5881 caactggtga attgagaatg ataaaaataa agaaatggga aaaacataag tcaagtacaa
     5941 gaatagagtt tctagcaggt aaaagggcag tggatgaagt attgaagagg gatatatatt
     6001 tgactaaaat atgtagatat ttaagctgta gtgaggaaga tgctataaat ggtattgtaa
     6061 atctaaatag taaagtggaa gaggctttaa ttaaaaaaag aaggcttgaa gaagtagtat
     6121 ctacatatca ggtcaaagaa atgattgaaa aagcaaataa ggttggcaat atttcggtca
     6181 ttaaaaaaat ttatgatgat gaagatttga aatatgtaaa taagatagca aataaaattg
     6241 cagaatatga aaatagtatt gcattattag ctgttaaatt taatgataaa ataaatttag
     6301 tttttgcatg ttctaaaaat ttaaaagata ttaatatggg agttttatta aaggatgcaa
     6361 taaatcttat agatggcaag ggtggtggaa gtaaagtatt agctcaagga ggaggtaaga
     6421 ataatggaaa tttagaggct acacttgatt atgcatttat gaagatagaa aaaactctat
     6481 aaatatatta tataaaaaac cttagtagat aaaatagata tggaggaata agtatggagc
     6541 aacaaaagga ctacatagag ttatatgaaa atgaagaact aatagagata agagaagcac
     6601 gtatggatga tttggataca atagcaaaat ttaattataa tttggctaaa gaaactgaag
     6661 gaaaagaact tgatatggat gttttaacta aaggtgtaaa agcattgtta ttagatgaga
     6721 gaaaaggaaa atatcatgta tatacagtat ttgataaagt tgttgcacag attatgtata
     6781 catatgagtg gagtgattgg agaaatggaa atttcctttg gattcagagt gtatatgtag
     6841 ataaggaata tagaagaaaa ggtatcttta attatttatt taattatata aaaaatatat
     6901 gtgataaaga tgaaaatata gttggaatga gattatatgt agaaaaagaa aacataaatg
     6961 caaaagcaac atatgagtct ttaaatatgt atgagtgtga ttataatatg tatgaatacg
     7021 aagtaataca ttcgtaatat aaatttgtaa tactgttata ctgatgttat aaagtattga
     7081 ttatattgac gattatatga aataaactgg atattataat tagaattttt agggggtata
     7141 aaaatgggcg ttttaaaagg aatgttttat gtatttttat ttttagactt agtgtcaata
     7201 ttctgtttct ttttcaataa aggaaaaata gcatctaata aaattgtgtt taatgcaata
     7261 ggagtactta catttgtact ttgttttatg ctttttagtt attatcctaa taataatctt
     7321 attggaaaat ttattgcttc tctatttttt atatttggag ttgcaggagt tatgttgaaa
     7381 gaaaaaaatt ttttatatgc tagacttctt ttaactgtag ttatagtttt ttctacatta
     7441 agattgttcg ttattcaata aaatgtattt gtatgaaaat ttattaaagt ctacacattt
     7501 aagtgtaggc ttttttgatt ttttgtttga aaattaagga aattttaagg aaattttaaa
     7561 atcgtcttaa atatttattg atatacttaa aatattaata gcgaaaggag acttatcagt
     7621 gatagaaagt aaaaagtcag aaaaattgtt actgtcaatt atatacataa tatttttggt
     7681 atatatttta atgattataa gaataatttt atttagagat gtaccaattt acgctatttt
     7741 caagggaacg tttaggaatg taaatttaat tccattttat acaatatatc aatttatagt
     7801 agatagtaat cttgacttta tgaaagctac tgtaaatatt atagaaaata taggtatatt
     7861 tattcctatg ggaatttttt tacctatagt atgtaaaaat ctaaataaaa aaactataat
     7921 tatagtaatt atacttgtta gcctagcatt tgaattaaca caatatattt ttgctcttgg
     7981 aagtagtgat atagatgatg ttattttaaa ttcattagga ggcataattg gaattaatat
     8041 ttacataaac atgaataaat tatttcccaa tgatattaac agatttaagg ctataatagg
     8101 tactagttta gttttaggag ttataggatt aggagttatt tctaaaaatt atcataactt
     8161 actaactttt aaatttagac ctgatagaaa aatatcaaaa atattaattg aagaaaatag
     8221 ggaaataatt aaagatataa ataaagatac agtagatata gttgggacat ttgagagctt
     8281 taaaaaagga ataataacta ttaaagcagg ttctaataac aaagtaaaga gaccagagaa
     8341 tttaattgat tctgatggaa atataagaat ttatttaaat gaaaatacaa aattagtatc
     8401 ttatataatt accaaagaat caaaaatgga tatagttaaa tatgaggaat ttgatgtgaa
     8461 gaatttagat ttattaagga gatatgatac tattaatgtt tggattgata aagaaaatca
     8521 gccaaaggat aaacatggta ttatggctag taaattatta attggattgt atgaataaaa
     8581 tattaaacaa gaataaaaga ataacaaata taaaaaacga aaaaactatt tctataatta
     8641 tttttacgtt gtgcataaaa taagaacatt agtgaaggag tagagataaa ttatggagat
     8701 aataaaatat attttgtact tttttatata ttcattttta ggatggacag tagaaagtat
     8761 aggatgttct atagcaagca aaagaataat caacagaggt tttttaaatg gtccaatatg
     8821 ccctgtttat ggttttggag cggtaattgt gatatcacta ttgggaagat ttaataatgt
     8881 agtaatagta tttctattag gaatgatttt aactacgata ctagaatatt ttacaggatt
     8941 tattttagaa accttatttc atgctaaatg gtgggattat tctgacagaa aattcaatat
     9001 aaagggtaga gtatgtttaa aaaatgcaat atactttggt gtaatgtctg ttttaataat
     9061 aagatttata catccattta taaaatattt tgtaagtata attccatata gaatattaat
     9121 ttcaatggct ataattacaa cactttggac tatacttgat ttgattgtta ctattataac
     9181 acttaaaaaa ttagatataa agttaaactt attagacgat ataattacag accttaatga
     9241 tataaatgtg aaattggata aatttgatag aggagaaata caagctttat ttaaaacaat
     9301 aaataacgac gaattagaag ttagagaaaa aataaacaaa ataaatagta agttggaccg
     9361 tatagagtct aatattattt tacaaaaaag agttataaaa gcttttccac atataaaaca
     9421 taaaaaacaa caagagcaac tagaacattt taaaaaaatt attaatgaga aaaggtaatt
     9481 atacaattta atgaagacga atagaataat ggtatttata agatgatttt cagaggactc
     9541 tataaaaata gaatagagtc ctttattttt tgaaaaataa tgtttatttg ataaaaataa
     9601 aatatattgt ttctgaataa caaatatttt gaaaattata aaaacatata ttgacaattt
     9661 gtgtcaaaaa tactaacatt aagtatataa agaattttat atgagaatat ctttataaat
     9721 cgcaataatt ttaaaacata aatttattta aagaggggat gatttgccaa tgagcgagat
     9781 aactagtcaa atgataagta cagaagaaaa aaaatatgtt gctaaaactc aaaagatacc
     9841 ttattatcca gtagcattta aatcaggtga tggtgcaatg ctatatgatt atgaaggtaa
     9901 tgaatatgta gattttttag caagtgcagg ctctgcaaat gtaggtcatg gtaataagga
     9961 aatctcacaa gcagttaaag aacaaatgga tgatataaca caatatacac ttgcatattt
    10021 ccatagtgat cctcctgtaa aattagctga gaagcttgtg gaaatagccc ctggagataa
    10081 tgataaaaaa gtactataca gtgcaactgg ttctgcttgt atagatgctg ctataaaatt
    10141 agcaagaggg tatactggaa gaacaaagat aatatctatg tgtgaatctt atcatggaag
    10201 tacttatgga gctatatcta tatctgcttt aagtacaaat atgagaagaa aaatgggtcc
    10261 attgttacca gaagtttatc acttccatta tcctgataaa aatagaacag ctaaagaatg
    10321 tttagatgag atagaatatg cttttgcaca ctatctacca gcagaagagg tagctgcaat
    10381 atttatagag ccaattgcag gagatgcagg aataatagtg cctccagtag agtgggtaca
    10441 aggtttaagt aaaatatgta aagaaaatgg aatattactt gtaagtgatg aaatacaaca
    10501 aggtatggga agaacaggta agtggtttgg tatagaaaat tttggtgttg aagcagacct
    10561 tatagttctt ggaaaatctg ttggaggtgg attacctcta ggagcagttg ttggaagaac
    10621 agaaataatg caaagtcttg atgcaccagc acatttattt actttagctg gaaacacaac
    10681 agtatgtgtg gctgctttaa aatctataga gataattgaa aaagaaaact tacttcaaaa
    10741 gagtatagaa atgggagatt atattaaagc aggatttgaa aaactaaaag aaaaatacga
    10801 tataattgga gaaataagag gcataggatt atctatagga gttgatatag ttaaaggaaa
    10861 aggttctaat gaaaaacatc cagatgctac agctaagata tgttatagat gtatacaaac
    10921 tggattaata atgatattct taggacaatc tactttaaga gtgcaaccac ctctagtaat
    10981 aactaaggag caagtagata aagcaatgaa catcatagat tctgcaatag atgattattt
    11041 aaatggtaga attggtgatg aagtatatga agtaactcaa ggttggtaaa ataaatatta
    11101 aatgaaaata ggagttatct caattttaga aaattatttc tgaaatgaga taactctttt
    11161 aagttaccca caaataagaa aattgtttga ttcattaaag actatatttc ggatgtcgtt
    11221 tttgtgagta tcagagacag tattacgaga ataattacct ttattcgtac tatctgttaa
    11281 tttagttata attaagatag ctaaaagaat aagaattact gtgtataaag caataacata
    11341 tggttttctt ttatatttgt atttgttatt gaaaaaagaa tggccataat tatttttatt
    11401 tactttagat gtatttgtat tctttttctt gttacctttc tttttatcat ccttttttct
    11461 atttttaggg taaggaatga ctttgtgtgt attatcaagt ttgatatttt tatttttttg
    11521 aatattgttt tccaggctag cctttttttc tccaaattga atagttttat tggtattgtt
    11581 gttatctttc aatgttaatc tccctccctt aaactttccc tttagataat attactacta
    11641 acctatggaa tatacaataa ataatatata agtaataaaa ttttataggt ataaatctct
    11701 ttctccacgc tctaaggcag tcatattgtt agatactatg tttcttatat cttctctttc
    11761 tatcttacct atttcttctg cgataagttt tttacccata attttaagtt cttcatctcc
    11821 ataatcgatt aaaaattcat ttaatgtagt aagagcattt ggtgtacata cattatggat
    11881 ttgtcgactt ttagctaagc tcatgaatct atcgccagtt ctacctttac gataacaagc
    11941 tgtacaataa ctaggtatat atccatcagt aatcagttct ttaagcacct caacagggct
    12001 tctatggtct ccaacttcga attgttctgt attgtcacca tcttcatatg ctttatatcc
    12061 tccaacacct gttagagaac ctgcactaat ttgtgataca ccatatttta gtaactcatt
    12121 tctcatttca gcagtttctc tagtggacat tatgattcca gtaaaaggaa cagctaatct
    12181 agttatagct actatttttt tgaacatatc gtcagaaact aagtgaggaa aatcttctaa
    12241 gctcatacct tcagcttttt tcaatctagg gaaagatata gtatggaaac ctacaccaaa
    12301 tttttcctct aagtgttcgt tgtgcatcat aagtcctaga acttcaaatt tagggtcaga
    12361 taaaccaaat aaaactcctg caccaacatc atcaacacca gcttccatag ctctatcaaa
    12421 agctgttaaa tggtaataat agtcattttt tatagattga ccatgcattt ttataaatgt
    12481 tggtttgtga taagtttctt ggaataatat ataagttcct attccttttt cttttagtaa
    12541 tttatactca tctacacttg tagctgctat gttaacgttt acccttctta tatttccgtt
    12601 ttcattatat gttgaataaa ttgcatctaa gcaatctaag atgtaattta tatcacaatt
    12661 tttagggtct tcaccagctt ctagagcaag tcttttatga cccatttttt ctaatatttt
    12721 aacctcttct tttatctctt ccatggtaag tttttttctt ttaaatttgt tgcatttact
    12781 aaaaccgcaa taaacacatt catttacaca gtagtttgat acataaagag gggcaaataa
    12841 aaccactcta ttaccatata tttcattttt tatttgccca gctatactaa ataatctatc
    12901 tagttgtttt ttatcttcca cttcaagaag tgtagctata tctttataac taagtttttc
    12961 ccttctatca gccttatcaa gtaccttttc aatatcatca gaagttgaat tttttgcatc
    13021 ttctaataaa gaattaataa gttcatggtt tatgaacatt tacaaacgcc tccattcaat
    13081 attatcaccg cgagaatagt caacttcaag tcctaatgac ttgatgtttt cttctaaact
    13141 ttggtgatat tcacaagctt cttgaccagt aaaggctttg ttatcgtaaa gagaatattg
    13201 ttttctaaat tcttgaggag aaaggtttgg cataattaca ttgcaaccag ctaaaagacc
    13261 tgcatttcta ccactagggt ttatagatgc caaggctgtt gtagcgggta ataaaacttt
    13321 tggaagtaga agtcttgtaa ttgaaagcat aagtaatgtc ttctctaaat ctccatgttt
    13381 ataatcctta aaaattgtat catggtgtgg aatgaaaggt cctattccaa ccatatgagg
    13441 atttaactct tttaggtata ataaatcacg aacaaggtct tcgttgttct gaaatggtga
    13501 ttcaaccata aatccagcac ctacttgata accaatttct ttaaggtttt ttaggcattc
    13561 ttttctagtt ctaagctcaa tgtttggcgg atgtaatttt ttataatgac tgtctgtagc
    13621 agtttcatgt cttaaaagat atctatctgc accacataaa aagtattttt tatacgaatc
    13681 ataactcttt tctcctagtg atagagttat ggcacaatcc tcatatttat tttttatact
    13741 tgaaacaatt tcacatattt tatcatcagt aaaatatgca tcttcaccac cttgcaaaac
    13801 gaatgttctg tatcctattt tataacctat atcacaacat tcaagtattt catcaagtga
    13861 aagcctgtat cttatgatat ttttattaga agattgtatt ccacaatagt agcaattatt
    13921 tttacaatag tttgtaagct ctataagtcc tctcaagtag actctatttc cataatgttt
    13981 atttctcatg tcgctagctt gtttataaag atagtttctt aaattttgtt cgaagttata
    14041 ttcctcattg tcgatatttt ctattaaata tagtagttca tcaaaactta atgaattaat
    14101 gctgtaaagt ttatctataa agtatttaat cttattttta gtcatattca aatatgtaat
    14161 tattaagtat agttaaattt ttaataattg aaaagttcaa gtgatctttc caaaatacct
    14221 tttacatatg ctattaagac accatagttt acaataggta cattgaaaga ttttgccttt
    14281 tctattctag ataacattcc agctctattc atcatacaag ctccacagtg aactacaagg
    14341 gcatatttat ttatatcttc agtgaaggat actccagaac taaattcaaa agtaatgttt
    14401 ttgccagttt tctttctaat catattagga atttttactg ttccaatatc atcagtttgt
    14461 ctatgatggg tacatccttc ggccatcaag attttatcac catcttttaa attttctaaa
    14521 gcataagctc cattaatcaa ttctttaagg tctccctttt gtctagcaaa caatatagaa
    14581 aaagatgtaa gaggaatatc ttttggtgta tctttatcta cttgtggaaa tacttgagag
    14641 tcagtaataa caagttttgg ttttttgcct aaattagata gagtttcttt taaactatct
    14701 tcttttgtaa ctatagaaat tgcaccatta tccaaaatat ctcttataac ttgctgttga
    14761 ggaagtataa gtctaccttt tggagctgct ttatctattg gaacaactaa aacaactaaa
    14821 tcatttggtt caattaaatc tgataccaat ttgaactcag tgctatcctt aggcaaaact
    14881 tttattattt cattttttaa attttcaatt ccaattttat ctgttgatga gacagaaaca
    14941 actggacatt taactttatt tttagttaag tttaaaattt ctgattgatt cttaatagta
    15001 tcaattttgt taagaattag aatatgaggg atattcttat cattaaattt ttcaattagt
    15061 gacaaatctt cttgtgatat accaatttgg caatccacta ctagtaaagc tatatctgtc
    15121 ttttctaaaa catctagtga tttacctatt ctaagttcac caagttcacc aacatcatca
    15181 agaccagcag tatctataag aacacaaggt cctataggaa ggatttccat tggtctaaat
    15241 actgggtctg tagtagttcc agcaatatct gagactattg cagcactttg atttgttata
    15301 gcatttatta tgctagattt acctgcattt cttttaccaa agagacctat atgtactctt
    15361 accgattgtg gagtagaatt tagactcatt tgtactcacc accttaaact tctttttttg
    15421 atatactagt ttttacagat acatgaggta tgttgcctaa tttaccagtc aaactattaa
    15481 tagtatccat ttcgccaaca actgctatac atacgattga gacaccttct tcttcgcaag
    15541 gaatgcccat tcttccttta ataatacctt taaaacctga tacaacctca ttgaatttaa
    15601 attgacattc ttttggctct tccaaaatag cacttataac tgcaaccttt ttcataaata
    15661 tcctcctaac tcagaaaata tgtcttaaac aaatccaaaa tcaaaaaact tttctttgta
    15721 aagaaaagtt tctacaaaag aaaagttatt aattacacaa gtataatgtg ctatattaaa
    15781 ctatttcctt acagattaga taactctttt ctggtagggt tagcttgtaa aaatttaatt
    15841 taacaacaag taactgaaga aaatttttat acaattt
//
LOCUS       DAEPXW010000088        15852 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.089, whole genome shotgun sequence.
ACCESSION   DAEPXW010000088 DAEPXW010000000
VERSION     DAEPXW010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15852
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.089"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            43..639
                     /locus_tag="KRM55_002827"
     CDS             43..639
                     /locus_tag="KRM55_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBH1595044.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(737..1696)
                     /locus_tag="KRM55_002828"
     CDS             complement(737..1696)
                     /locus_tag="KRM55_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1595045.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(1730..2461)
                     /locus_tag="KRM55_002829"
     CDS             complement(1730..2461)
                     /locus_tag="KRM55_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595046.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(2454..3224)
                     /locus_tag="KRM55_002830"
     CDS             complement(2454..3224)
                     /locus_tag="KRM55_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595047.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVVFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(3309..4019)
                     /locus_tag="KRM55_002831"
     CDS             complement(3309..4019)
                     /locus_tag="KRM55_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH1595048.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(4199..4351)
                     /locus_tag="KRM55_002832"
     CDS             complement(4199..4351)
                     /locus_tag="KRM55_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBH1595049.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(4377..6533)
                     /gene="feoB"
                     /locus_tag="KRM55_002833"
     CDS             complement(4377..6533)
                     /gene="feoB"
                     /locus_tag="KRM55_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH1595050.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLTSVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(6633..6854)
                     /locus_tag="KRM55_002834"
     CDS             complement(6633..6854)
                     /locus_tag="KRM55_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1595051.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(6867..7079)
                     /locus_tag="KRM55_002835"
     CDS             complement(6867..7079)
                     /locus_tag="KRM55_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1595052.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(7400..10297)
                     /locus_tag="KRM55_002836"
     CDS             complement(7400..10297)
                     /locus_tag="KRM55_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1595053.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDEESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(10624..11232)
                     /locus_tag="KRM55_002837"
     CDS             complement(10624..11232)
                     /locus_tag="KRM55_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBH1595054.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLFKCLA"
     gene            complement(11492..12037)
                     /locus_tag="KRM55_002838"
     CDS             complement(11492..12037)
                     /locus_tag="KRM55_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH1595055.1"
                     /translation="MKKFVCTVCGYIHEGDTAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(12155..13978)
                     /locus_tag="KRM55_002839"
     CDS             complement(12155..13978)
                     /locus_tag="KRM55_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595056.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTILSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(13991..15766)
                     /locus_tag="KRM55_002840"
     CDS             complement(13991..15766)
                     /locus_tag="KRM55_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595057.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRKRIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         5263 a         2835 c         1563 g         6191 t
ORIGIN      
        1 aattacttga tattaatttt catttgaagg aggttatctt ttatgtcttg ttgtaattca
       61 caattttgtt gtaaaaataa aattgaatca tcatatataa aatggctttt agaagtttta
      121 ggtccagtct ttttaggctc taaacctgct gaaataataa atatttcgtt tactgatgta
      181 aatagagagg aaaaaattaa tgatatttat aaatatctat ataagtgtaa gaaaatagat
      241 tttatagtta ttgataaaga aaaaaaggga ttaaaaatct tatttgtaaa taaaaaagca
      301 ttatcagaaa aattaaaatg taaaaaaaca gtaaactttt taaagttttt aggatacaaa
      361 caaaatacga atgttaatgc ttatttagag catttagtag ataaacttaa gagtgatgtt
      421 tttcctgatg aaataggtat ttttttagga tatcctctta aagatgtgat tggatttatg
      481 ggatatagta attatgaagt ttctatgatt aaatattgga aagtttatgg tgacacaaaa
      541 caatccgagg acacatattc gaagttttta cttcaccgta agaaaatgag aaaattacta
      601 gactacataa gtgtagataa aatagtaagc tgtttttaat tgtgtttttg tataataata
      661 aaaatacacc ctcttttacc atacagtttc cataataaat aagggtgtat tttccacttt
      721 aatattttaa agtattctaa ttttgattgt acaacatatc tttaatattt attttctttt
      781 gttgcattcc attagacatc aaaaattcct gtgtatcttc taattctttt atatccttgt
      841 ccgttatttt agaactaaag tcataccaag aatacatttc ttttgtttca tctaaagata
      901 aaccaacttc tttagataca acatccatca cttcatcctt gttttcattc atatatttta
      961 aagtttcttc atgaaccttc ataaatcttt ttactaattc aggatatttt tcagcaaagt
     1021 catcacttac agcagtaact attattccac ttactaatcc ttctccattt acaatcattt
     1081 tggcacctga atttatcgtt ttcaatgcca ctggacctgc aagcattgct acatcagcac
     1141 ttttactttc taatgcagaa gcagcactag gaatatccat atttacatat tcaacatcat
     1201 ctatagtata gccttcttta gcaagtgcag caatcaacag ttgatgaagt atagtccctt
     1261 ttggacctac aattttttta ccttttaagt cttttataga tttaatatta tcattattag
     1321 ttataagcat atatcctttt ggtgaacggc tataaatatt cgtaatttta agaccaacac
     1381 catttgatgc agctattatt gcagacgttc ctcctaatgc atgtaaaaag tctagctcac
     1441 ctgctgctaa tgcttgagtt tgctctggtc ctgttgtcaa ttcatggaaa ttgactttta
     1501 tattgtcctt tttaaattcc tttccaaata aatcatcctt tttttctaat atactaggaa
     1561 cattaagtgg tgattttaca taagttaaat ttatttcctt aggtaaacta gcctcttttt
     1621 ttgcaggttc atctttctta tcatttgttg ttgaacatcc tacagtccca accaacacca
     1681 ttattaaaga tgtcattact gctaaaatct ttttgtttct tttaatcaat taaaactccc
     1741 ccaattccct taatatttct tttttcaagt ttatataata gtttttagtt aaatctctat
     1801 tatattcatc ttcgacacta aattgtttaa tccttttatt tttactaaaa acaattattt
     1861 tctttgctat ttccatagct tcttcaatat tgtgagttac aaatactaca ccttttttag
     1921 tatttttatg gatatttaca acttcttttt gcatttttct tcttgtgaag taatctagtg
     1981 ctgcaaatgg ttcgtccatc agcaaaatat cgggattgaa ggaaagtgct cttgctatac
     2041 ttactctgtg agccattcct cctgataatt catttggata tgagttttta aacttttcaa
     2101 gcttcatcat ttttaaatac ttgtctaaat caactttatt tctattatct ttttcagtat
     2161 gtaaaagtat attttcactt acattcagcc atggcataag tctactttct tgaaatacca
     2221 ttcctacttt tggagtacac tttttatcat tattaaaaaa atatatgttt ccactagtag
     2281 cattttcaag ccctgctaaa attctaagta gcgttgtttt cccacatcca ctttcaccta
     2341 atataacagt tatctcttca ctagatatat ttaaagatat attatcaaga actaaatgct
     2401 ctttattatc aactaaatat ttcttatata tattctctag caaaaatcca cttctaacca
     2461 tttaaatcaa cctgcttccc tttgctaaat tttgttatta tctttgaaaa tagataatct
     2521 gaaagtatac ctaaaaatcc aataacaaaa attcctacca atacaacatc agttctagac
     2581 atatcttttc catcagaaat caaatatcct agtcctgaag aagctgcaat aagctctgct
     2641 ccaattatag ccctaaaact atacccaagc cctaaactaa gtccaacaac aatatccagc
     2701 atagaattag ggattattat tttataaaaa attctctttt tagataaatt aaaagattta
     2761 cctacttcta ttaatttatt gtcacaattt tttatacctt tcaatgtatt taaaaatatt
     2821 ggaaaaaagg atgccaaaat aataattata attttagatt cttcacctat accaaaccat
     2881 aaaataagca ttggcaccaa agctagtgga ggtgtacttc gcataaattc aaatagtggt
     2941 ttgaaatatt catacatttt tttatttact ccaaatacaa ctccaagtgg tatagccatc
     3001 aatgaactta ttaaaaaacc tattaatatc cttcttacac tggcataaac atttaagaaa
     3061 atagaaccgt catatatcat ttttataaaa gtatctaaga ctatttcagg aggaggcaga
     3121 atatagctac tccatatacc caaaacacat actatcttcc ataaaattaa aattattaaa
     3181 aaaatataat atcctttaag ccttttatga attttctcaa acatataaaa ctccttttaa
     3241 catatctatc cctgctaccc tttttatttt ttaatatctt aaataataat taagctatat
     3301 cataagattt aatctatgcc aagtcttaat ccacctgaac tcattctatc agaaggtgta
     3361 gaatctgttt ttaagccaga caatctttca gatggttgta taatgactat ttgtccaggt
     3421 tcaacaaatt ccatatgata agattctcct gaagtctgac caataaaagt cttccatgat
     3481 agttttgata ctttaggata tggttctctt ccagtccaag ctactaatgc atctgggtca
     3541 acacaacaag gtccttcaag aattagagga ttaccatctg ttattatagc aacatcttga
     3601 ttttgacctg ttttatttac taaatgtgta gtaaaaagac ctttttgaga tattacccct
     3661 gaaccaatca attttacact gtaatttaat tgttcagaaa atgccaataa gttttcactc
     3721 tcaacataaa tggaatcacc tgggtcaatt gatattacat ctacatggta agcattttga
     3781 gctaggtaaa tttcaccttc accttcaacc accattattg gcatttgttc tcctgtcaat
     3841 gacctctgaa catgacctaa taatgctctt cccaatccac cgccattact tggacctaac
     3901 agcaattttt caaaattaaa atttccttta aaggctacca tagcaccttt ttttgcaaaa
     3961 aatttaccac ttccccttgc tatacacata agctcgtttg taacatcaaa tttaaacata
     4021 atattcactt atattgctta atttagcaat aatccctcct aatcatatat ttatatataa
     4081 ttatacagta aaattacagc atagtctaac ctacttcaaa tatgaaattt gttatttata
     4141 caaaaaataa gaacctgata ataaagcaat ttaacttttt atcaggctct tatcctattt
     4201 atctcttagc gctatgacaa ctcttactac ttgagcatcc agaacaacca catccacaac
     4261 tgctaccatt cttttttgaa tttttaacca tatacattac agctagtgcc attaatacta
     4321 ctacaatagc tgctataata aatgtagcca tattcatcac tccttattta tatgaattaa
     4381 tttttcatat aacttaattt acccattttt tcttttttca tatttttatt tgaataagtt
     4441 aaaactacaa agactactgc tactgctata aatatagata ttattgcccc agcaatactt
     4501 cctccagtac ctaaaactaa acttccaact tgatttataa gaagagcaat tatatacgct
     4561 gttaaagttt ggaatcctaa tgtaatccat gtccatttcc atgaacccat ttctcttttt
     4621 atggctccaa tagctgcaaa acaaggtgca caaagcatat taaatgccat aaatgcaaac
     4681 gcactagcta ctgtaaacat gcttgcaact gaagtaagaa gtgttgggtc ttgctctgtt
     4741 gcatctgata taccaaataa aactccaaat gttccaacta cattttcctt agctactaga
     4801 cctgtaactg ttgctactga tgattgccaa tttccaaatc caagaggagc aaatattggt
     4861 gcaactatat ttcctaagct agctaatata ctatctccag catctaccat ttgtaatgac
     4921 caattaaatg attgtaagaa ccagattact ccacaagcaa caaatataat tgttcctgct
     4981 ttgattataa atgcttttcc tctatcccac atatgtatta aaacaccttt tgcacttgga
     5041 atatgatatt gaggtaattc cataacaaat ggagatggtt ctcctgcaaa taaactagtt
     5101 ttctttaata taattccaca aatgattatc attgcaatac ctaagaaata cattgatgga
     5161 gctacccatg aagcacctcc aaataatgcc cctgcaaata atgctattat tggaatctta
     5221 gctccacatg gaatgaatgt agttaacata atagtcattt ttctatctct atcattctct
     5281 atagtacgag ttgacataac tcctggaact ccacaacctg aacttataag cattggtata
     5341 aatgattttc ctgaaagacc aaacttacgg aaaattctat ccattataaa agctacacgt
     5401 gacatgtacc cacaatcttc taatattgat aataataaga ataaaagcat gatttgtggt
     5461 acaaatccta gtactgctcc aactccacca attagaccat caactacaag tccttgtaac
     5521 cattctgcta catttaaaga agctagaaaa ttacttacat tgccttgaat aatttctcca
     5581 aacagtacat catttgtcca atcagttgct atagtaccca atgaacttac tgctatatag
     5641 taaactcccc acattataag tgcaaaaata ggtaatgcta gtatacgatt tgttacaatc
     5701 ttatctatct tatctgatac agtttcctta ccttttcgat tcttctttat tatacttgaa
     5761 attattgaac taataaattc ataacgattg gctgttatta tactttcact atcatcatcc
     5821 aattcatctt cacaatttct agttatttct tcaatactat tcaatattgt tttagaaata
     5881 tcaagttttt gtataacatt ttcatctctc tcaaatagct ttatagctaa ccagcgtgtt
     5941 tctacatcta tatatggagt cttttcttct attatttttt caattttttc tattgcatcc
     6001 ttactttcat caacaaaggg taatttgaaa tttaatttat tgttactact tgcaagttca
     6061 actgcctttt cagcagcctc cataattcct tgacctttaa ctgctgttac ttctaccact
     6121 gggcaaccta taacttcaga tagttcttta atatttatct tatcaccatt cttatttaca
     6181 atatccatca tattaagagc tataacggtc ggtataccta gctctaaaac ttgagttgta
     6241 agatataaat ttctctctat atttgatgca tctacaatat ttattactgc atccggctta
     6301 tcatctagca taaaattacg tgtaactact tcttctaatg tatatggaga taaagaataa
     6361 atacctggta aatctactat ttccacatct ttatttcctt ttaattttcc accttttttt
     6421 tcaactgtta ctcctggcca gttaccaaca tattgtgatg agcctgtaag cccattgaac
     6481 attgttgtct taccacagtt aggatttcct atgagaccta tttttattga catttccatt
     6541 ccctccatta ttatttaaat acatcactgt ttgtgataca gaaaatcatt ctcattatat
     6601 aattacatta accctactct aattaatctt tattattcca caataatttt ttctgcatct
     6661 gacttacgaa ttgatagttc ataatctctg actgttacct caattgggtc accaagagga
     6721 gctacttttc ttataaatat attaacacct cttgtaatcc ccatatccat tatacgtctt
     6781 cgtgtagctc cttctccttc taactttttg acttttacag tctctccaca cttaatatcc
     6841 ttcagtctgt tcatgtcatt acctccctat attattattc tacttgccat ttttttatct
     6901 aatgcaactc tagtatcttt tacgtctatt attaagttac catctatctt agaaactatt
     6961 ttaacatttg tacccactac aaaacctata ctatttaaaa aagtcctcgt cttatcactt
     7021 cccgaaattt tctttataac tacttcttca cctgtatttg ataatatcaa tggcatcata
     7081 taatatccct cctcttaaag taatttaaat ctacaagcaa tcgttatctt atatataaat
     7141 tacaatacct taaatcttaa tctattaaaa taatatccta ttttttcctt ctttttacaa
     7201 ttcctaattt tgatttaagt ctatcacaat agtatatttt ttgcaagtga ttattgtatt
     7261 ctcttgattt tttttctcat ttgatttatt ttattaataa aatcgtaaaa attaatacaa
     7321 aaataaagat gctctaaaat agtatactca actaatatta aagcaccttt attatatatg
     7381 tcattattta cacattgctt tattcttttt taaaagcgat tttttcaaac tcttttacag
     7441 gcattggctt agaaaacaaa tatccttgta ccatatcaca cccaatctgc tttagaaatt
     7501 ctacttgcga aatagtctct acaccttctg atattacttt cattttcagt tcctttgcca
     7561 ttttaatgac attagatata acaatttttt cattattact ctcatctttt tctgtaaaaa
     7621 atgctctatc tagttttaat atgtcaacag gcaattcttt taaaagatta agagaggaat
     7681 atcctgtacc aaaatcgtcc atagagatta caaatccctt ttctttcaaa ttgttcattg
     7741 tatcaagtaa tccttctata ttatctaata ctgctgtttc tgttagctct aattctataa
     7801 gtcttgtcgg aattttgtat ttatctacaa ttaatttaaa cttctctata aaattactat
     7861 ttacaaaatg cattcgagac aagtttacag atataggtac tactttttgt ccttcatcca
     7921 tccattctct aatcttttta cacacttcct caaatacata gaaatcaata tttacaataa
     7981 aaccattcct ctcaaataca ggaataaatt ctattggtgg tattagacct ttttgtggat
     8041 tatcccaacg aacaagagcc tctgccccta taatctgata atctgaaaga ctatatttag
     8101 gttgaaaata aacaataaat tctccattat taagagcatc taccattgaa ttttcaattt
     8161 ctttctcttt taatattttt ttgtgcattt ccttatcgta aaaagcaaat gaatttttat
     8221 gaccaccttt tatagttttt cttgcagtat tagctctatc cataatagta tttatgtcat
     8281 tatcactttt acttatttta tatataccac aatctaaaat caatttataa tagtttattt
     8341 taggattact aagtatttga accttattgt aaatattgtt taaccttgtt ttaatatcat
     8401 catctgtctt atacttaata agaagaacaa aatggtcagc agaaactctt gcaaaaattt
     8461 catcttcctt taattcactt gcaatagtat ttgatatatg tatcaaagta tcatttccca
     8521 tatcatatcc aaacatatca tttatatatt taaatttgtc aacatctata taaaacaacg
     8581 catattcttc tggattattt ttagcaaaca gtttattaga atttatttta aatttatcta
     8641 tactatctgc tcctgtcaat gggtctgtat atgctatctt ccttagataa tcctctttct
     8701 tctttttatt ataaattata tatttaatag caattaagaa taaaatacat acaaaagaaa
     8761 taatttgtat tgaatattct ttaaaaatca caccaaatgg tactttataa ggtttgtcaa
     8821 tagtattaga atatatacaa tcacttaatt cttcttcagt aattttgtct attgatttat
     8881 ttaaaataga cactaatata gggtcagttt tatttgatac ccctatacgc atcccatagc
     8941 ttgtatctaa aacagatata acagataaat tctcactctt tccttctctt aaaagttcat
     9001 caaactgata agagctaagt atcattaagt ttgctttacc ttcatttata gcgtttagac
     9061 aactttctac actcttataa gatgttgtct tagcattttc aaaactcttt tctatataag
     9121 aatcaataga cttataacta ctagttaaag caatatttaa atcattattg agattggtat
     9181 ccaattttcc taccataatc attggaatat ttatgtatgg atttgtcaat ttcatattaa
     9241 atcgttttgc cttatcattt tcattgattg agccacatag catagttgcc ttaccacttt
     9301 ttatgtaatc aagactctca ttataatttt ttgttttaat atattcaaat tttataccac
     9361 atttttttga tataattgac attaaatcgg aacttatacc tttaaatgaa ttgctttctt
     9421 catcataata ctctacagga gaccactctg aatcatatac catagtaagt tttgggtttg
     9481 ctttaataaa attcatttct tgccgagtaa atgctatgga attattgacc tctcttttga
     9541 aatatttttt atataattcc aactcataat acatatcatt tatttttaat tcttttaaag
     9601 cataatctaa ttcttttacc aaattaggtt tatcttttgc agtagcaaaa taaaaaggtt
     9661 ctactgaaaa tttgctaact attttcattc ctttagcatt tataatactt ccacaaacaa
     9721 atgcatctgc ctttttttca ttgacggact caattaattc atcaatagaa ttacagtata
     9781 tatattcaac tgaaaaatta ttttcttctc tatacttctc aaatgcagta ttatgaaagt
     9841 ttcctctaag tacagctact ctcattccct taaaggaact tatatcttca taaaacatat
     9901 tattgttact atcctttgta tatagtgcac tatattcata tcctgaactt agtttaggaa
     9961 aattaaatag tttatttctt tcatcattct tctgtaaagg tccgagtaag tctatttcac
    10021 ccttttctag tctgtctaaa cattcttccc aagacccttt tacaaattca tattcccatc
    10081 ttgtatattt tgagatttct cttagataat cataaccata tcctgtataa gaatgctctt
    10141 ttgatgagga tattattccg tagtcatcac aatatccaac tcttattttt tttgaatttt
    10201 cagactcatc agcaaagcat agtatattgt taaaacatga tataataagt aaaaatatca
    10261 aagaaagtat caagaagtgc tttttaaatg ctttcatatt taaaaacctc caatttgcca
    10321 acttacttta acttatttgg ttttctagtt gtaactactt ttattgtaat ggtaaatata
    10381 tcaaattgca atattctcat ataatattct tattcaacta taataaattt attattatct
    10441 atttaaatac actatctaat attagtttct tataagtcat aaaagcacaa ctaacactat
    10501 aattctagtg attaatttta tttcaaaaaa tataataaca ctactaatat tttaaatatc
    10561 aatagtgtca taaaaacttt tcagattaat taaatctttc tatatatttt ataataatct
    10621 aaatcatgct aaacatttaa acagaaaact tttttcttta atagtaaata cttttgtttg
    10681 aatatcagaa taattatttg aatatctatc tataaaacca tggtttgcat ctaaaatctc
    10741 aatttggata ttttgtttcc tagaaagttg gtaagaaata gaatcaacat caaatgaatc
    10801 gtgctttgca aatactaata aggtaggaca ttttggaatt acatccatgt aatctcgaat
    10861 ccgagagcca taacaacaaa ttatgccatc acaaaaagaa tcttcactgc atctccatgc
    10921 aatagttgct cccacactat acccagcaac aaatacatat ttatactctg attttaaatc
    10981 atttataagc ttttcaactt ttttataaat atcaaaacca acattattta taaaaaaatc
    11041 atatgcctct tggacttttg aatatggaaa aactcttttt tctcccagaa gttcaggaca
    11101 aaatacatca tatccatatt tataatactt ttgacaaaca tcttctataa agctattaat
    11161 cccatagatt tcatgcaaaa caacaatagc tacatcactt ttatgtatat actttatcag
    11221 attatccacc acctttacaa aacagcaaat tttttatact tagtttaata tattcttctt
    11281 tacatgtcaa tttacttttc taaaatcaaa tttatttttg gattaatcat ttatttttaa
    11341 aagttgtgca ttattactat taaattattc tctattatta aaaatataat cattagaaat
    11401 aaaaaataaa gtacaaataa ttaaaaaata tctcactcat aactttaaaa attataagtg
    11461 agatactcct aaaatctact ttatattaaa tttattttcc aaaatatcta tttaataatc
    11521 ctaagaatgc tttaccatgt ctagcttcat ctttacacat ttcatgtact gtatcatgta
    11581 tagcatctaa tcctaattct tttgctttct tagctaattt taattttcca tcagttgcac
    11641 catactcagc atcaactcta actcttaagt tttcttttgt atctgcaact acaacttctc
    11701 caagaagttc tgcaaattta gcagcatgtt cagcttcttc aagagctatt ctcttataag
    11761 cttctcctac ttctggataa ccttctctat cagcttgtct actcattgct aaatacattc
    11821 ctacttctgt acactcacca acaaagttag ctcttaatcc ttcgattatt tcttcatcta
    11881 caccttgagc tactcctatt ctgtgctcat cagcccaatt tttttcgcct ttcatttctt
    11941 caaatttatc agctccaact ttacatactg gacattgtgc tggtgcagta tctccttcat
    12001 gtatatatcc acatactgta caaacaaatt tcttcataat tactttcctc ctaaatttta
    12061 tatatcaaat taaatttttt atttattaag ttagtctata tatacccgca ccatatacct
    12121 ttaaacaatt tttttaaaag ttttttctaa atacctattt tccctgtgtc aataatatgt
    12181 ttctataata atgtcccttt aattttatca attctttatg atttcctgat tccacaattc
    12241 taccattttc taaaactatt atattatcac aatttgatat ggtacttaat ctatgagcta
    12301 taattatact tgtctttcca taagttaaat tatttattgc ttcttgaatt ttagcttctg
    12361 ttgctatatc tatgttactt gtagcctcat ccaaaataag tattggagca ttttttaata
    12421 ctgctctagc aatacttatt aattgttttt gaccttcact taaatcttca cccctatccg
    12481 ataatatagt actatatcct tcacgcattt taactataaa tttatgtgca tttgctattt
    12541 tactagcata tataacttct tcatcagtag cctccagatt tccatacctt atattttcca
    12601 taactgtatc attgaatata taaccttctt gtggaactac tccaaaacaa gttctcaaat
    12661 agtttctgtt aatagagtat atatccttac catctaaaaa tatacttcct tcatctatat
    12721 gataaaaatt tgtaattaga tttataatag ttgtttttcc acttcctgtc tctcctatga
    12781 tggcatttga tgtgccagct ttgattttta ggtttatatt atctaaaatt ttcttttttg
    12841 aatcataaga aaaacttaca tctttaagct caatttctcc ctttacaaaa tgagagttta
    12901 aattaccatc tttattatcg ttaatctcac ttttaaacat gttatgcact tcttgctctt
    12961 cttgttcatc tataatttca aaaactcttt cacatccagc tatggctgaa agtaatgtat
    13021 taaatagatt tgctaattca tttaaaggtc ttgtaaattg tcttacataa cttaaaaaac
    13081 tagctataac ccctatggtt ataatatctt tagatgcaag aatgcctcct ataatacata
    13141 tagttgcaaa tcctatatta ctaatcacat tcataatagg cattaaaaga gaagtgtaaa
    13201 tttgcgattt aagggaaata tttagaagtc tatcattgac ttctttaaaa tcatttacag
    13261 attttctttc ataattaaaa gattttacta catttatgtt tgatatcatt tcttcaatat
    13321 gtgcatttag ttttcccaac tcaacttgtt gttgcttaaa aaaaactcta gttctctttg
    13381 caataaaatt actcacaaac attactatcg gtattaatat tacactgcaa aaggttaaaa
    13441 ttgggcttaa tacaaacatc ataataaaag tcatcaatat gtttaagatt cctgtaatta
    13501 actgtactaa tgaatttgat attcctgtac tgatattatc aacatcattt gtcactctac
    13561 tcataatatc tccagtagaa cttttatcaa aaaaggttat tggtagattt ttaaatttta
    13621 aaaataaatt acttctcatt tctctgacta tactttgaga taatctagct gtacatatcc
    13681 ccttagacag tttaactgaa aactcaatta tataaaatga aagtaaaata attattcctt
    13741 ttaagaaaat ggattttgaa taagtatcga tatctattat gtcaactacc tttccaatag
    13801 tatatggtat tacagttgat ataattgaat caattattac tagcaaaaaa ataaatctag
    13861 taatcttctt atctttttta aagtacataa aaattctttt aaacgttttt ttaaaatctt
    13921 taggcttttc ttttttcttt aatctactga ccttctgatt tccagtactt aaattcaata
    13981 tacttcctcc ttaatttaca tcttcactta ctaaattttg caacgcaaaa atttttttat
    14041 aaattggaga actaaccagt aaatcttcat gtgtagcaaa tccaaccacc tcaccctcat
    14101 ccaagactaa aatcttatca cagtcaatta tagaactaat cttttgtgaa atagttatta
    14161 cagtacattt cttactttcc ttttctctta aattacttat atactctttt atattctttc
    14221 ttataattgt ttctgtatta atatccattg cactaaaaca atcatcaaga atcaatattt
    14281 gtggtttttt ggctatagct ctagctatag taattctttg tctctgtcct cctgataaat
    14341 ttttacccct ttggaataaa acttcatcat aagtattttc gagttttgtt ataaattgat
    14401 ttgcatttgc tatttcacat gattttacaa catcctcttt gcatatatct ctatttccca
    14461 taactacatt ctccaatata ctttttccaa acacactact attttgaaat actacaccta
    14521 ttcttttcct taaactttct tcagaaatac tgtatatact acgtcctcca atcttaatat
    14581 cacctttatc aattatatat aatttttgaa ttaaatttac taaagaagtc tttcctgaac
    14641 cagtttgacc aatcacacca atattttgac cttcttctat tttaaaggat acgtttttta
    14701 atattttttc atctgtattt ttgttatatg aaaaatctac attttcaaaa attatatcac
    14761 aatttacaaa ctttaaatct ttttctccaa catctaaact ttcttctctc tcaattactt
    14821 cttcattctc atcaaccaaa acctcactta ttctctcata agatgctttt gccctaacaa
    14881 aaacattaaa aacatgtgaa atcattataa gagatgttaa tattctagtc atatagttta
    14941 cataagcaac tataatccca attttaattt ctcctgaata aattaaatgc cttccaatca
    15001 gtaatattat tattatggaa acattaatga ttattgtaat tgtcggtcta aaaaatgaca
    15061 tcatagttgt agcttttcta ctatttttaa aaagttcatc atttaactct tcaaagcttt
    15121 ggttctcata atcgtatcta caaaatagtt taactacttt tattccactt aaaaactgtc
    15181 ttaattttga atttacttta tctgtacttt cttgtacatt tttaaataat ctatacccta
    15241 tcttcatatt aagcaatatt ataataaata taattaaaac tgcaattaga ataattattg
    15301 acatctttaa atttaatttt atagctataa ttaaacttcc tatacacatt attggtgact
    15361 ttataaaaac tctcatcatt ccattaacga attgttgcat ttgattgata tcattagtaa
    15421 ttcttgttat taatgaagct ctaccaaatt tatctatttg ttttaatgag tatgtattta
    15481 tcttttcaaa tacatcctgt cttaaatcat aagaaaaatg ctgagaaact cttgccgaga
    15541 ttacacttct tattattgca aatattgcac ctaaaaaagt tatacctatc attatagctc
    15601 ctgttgatag tatgtagtct aagttcttat ttgaaacccc tatatctatt atttttgcca
    15661 ttatagttgg ttgagctaaa tcacaaaaag cttccaatgt taaaaaaaat actgctgtta
    15721 gaaataatac tatatatttt tttatgtatt ttttaaaata cctcattcaa tcatcccttc
    15781 atagaatttt ctcattacca aaagtatatc ataatggcta atttaattga ttatatcaat
    15841 tataaatatt tg
//
LOCUS       DAEPXW010000089        15805 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.090, whole genome shotgun sequence.
ACCESSION   DAEPXW010000089 DAEPXW010000000
VERSION     DAEPXW010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15805
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.090"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(18..1211)
                     /locus_tag="KRM55_002841"
     CDS             complement(18..1211)
                     /locus_tag="KRM55_002841"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBH1595058.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(1234..1899)
                     /locus_tag="KRM55_002842"
     CDS             complement(1234..1899)
                     /locus_tag="KRM55_002842"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBH1595059.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSNNHKSNIDKDFLFK
                     NGF"
     gene            complement(1933..3045)
                     /gene="ribD"
                     /locus_tag="KRM55_002843"
     CDS             complement(1933..3045)
                     /gene="ribD"
                     /locus_tag="KRM55_002843"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBH1595060.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKASNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(3177..3298)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3487..5970
                     /gene="recQ"
                     /locus_tag="KRM55_002844"
     CDS             3487..5970
                     /gene="recQ"
                     /locus_tag="KRM55_002844"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBH1595061.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      6059..6170
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6312..7613
                     /gene="thiC"
                     /locus_tag="KRM55_002845"
     CDS             6312..7613
                     /gene="thiC"
                     /locus_tag="KRM55_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBH1595062.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            7667..7861
                     /gene="thiS"
                     /locus_tag="KRM55_002846"
     CDS             7667..7861
                     /gene="thiS"
                     /locus_tag="KRM55_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBH1595063.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            7854..8657
                     /gene="thiF"
                     /locus_tag="KRM55_002847"
     CDS             7854..8657
                     /gene="thiF"
                     /locus_tag="KRM55_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBH1595064.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            8720..9490
                     /locus_tag="KRM55_002848"
     CDS             8720..9490
                     /locus_tag="KRM55_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBH1595065.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            9507..10610
                     /gene="thiH"
                     /locus_tag="KRM55_002849"
     CDS             9507..10610
                     /gene="thiH"
                     /locus_tag="KRM55_002849"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBH1595066.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            10611..11300
                     /locus_tag="KRM55_002850"
     CDS             10611..11300
                     /locus_tag="KRM55_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH1595067.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            11488..12882
                     /gene="yfcC"
                     /locus_tag="KRM55_002851"
     CDS             11488..12882
                     /gene="yfcC"
                     /locus_tag="KRM55_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBH1595068.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            13399..14766
                     /locus_tag="KRM55_002852"
     CDS             13399..14766
                     /locus_tag="KRM55_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBH1595069.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            14791..15399
                     /locus_tag="KRM55_002853"
     CDS             14791..15399
                     /locus_tag="KRM55_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBH1595070.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            15447..>15805
                     /locus_tag="KRM55_002854"
     CDS             15447..>15805
                     /locus_tag="KRM55_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBH1595071.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYD"
BASE COUNT         6076 a         1770 c         2681 g         5278 t
ORIGIN      
        1 tatcatcata taatcattta tataatatct aaaagatgtc ccattttatc ttttttagtt
       61 tttaaatata gcttattaaa gtcattaatt tcttcattaa tagggattct attttcgatt
      121 tttattccat atttctctaa ttgatttatt ttatctgggt tattacttaa aagatttata
      181 ctttttatgt ttaaattttt taatatttga gcagccatat agaaatctct catatcttct
      241 tcaaatccaa gcattaaatt tgcttcaaca gtatcgtaac cttcttcttg aagtttataa
      301 gccttaattt tatttaaaag accaatacct ctaccttctt gcttcatata aattaaaact
      361 ccacttccat tttccacaat tttcttcata gaagattcta gctgtaatcc acaatcacat
      421 tttagagagt ggaacacatc tcctgttaaa cattcagaat gaagtctaac tagagtattt
      481 tctatattta tatttccata agtaagggca atgtgttctt catttgaata agtatctcta
      541 tatcctatga tttcaaaatt tccatatttt gtcggaagga aagcactaga tactttttct
      601 atagtagttt catttatttt gcggtattct ataaggtctt ttatagtgat gatttttaaa
      661 ttatgctttt ctttgaaaat cattaaatca tcaactcttg ccattgtacc atcatctttc
      721 attatttcac agataagacc aatctcttta aaacctgcaa gtctagcaag gtctactgag
      781 gcttctgtat gtccatccct gacaagaacc ccaccagttt ttgctattaa aggaaagatg
      841 tgaccaggcg ttttgaaatc tttacttgta gaattttcat cacagaataa ttttacagtt
      901 tcagctcttt catatgcaga tataccagtt agagtatctg ctccatctat agtaacagta
      961 aaggctgttt gaaatgtatc tgtattttct ctaaccataa gaggtatatt aagactttta
     1021 aatttttttt cagtggcagg tagacaaatt agacctctac catatgtagc cataaaattt
     1081 attgattcag gagtagccat ttcagctgcc atcaataaat ctccttcatt ctctctactt
     1141 tcatcatcaa ccacgattac cattttccca ttttttatat cttcaatagc ttcttcaata
     1201 gtattaaaca tgtaattcac tcctttatta tttttaaaaa ccatttttaa ataaaaaatc
     1261 tttatctata tttgatttat ggttattact attagaattt aattccttgt agttattagc
     1321 cataaaatta ttaacatact ttccaattac atcgctttct aaattaacga aatctccaac
     1381 attctttgtc aagagaatag tgttaatttt agtatgaggt ataatagaaa ccttaaatat
     1441 ttcatcatct aaatatgata tagttaaact tacaccatca atagcaacag aacctttgag
     1501 tatcattgag gataaaagtt ttttatcagg tcgtatactt actaaaactg cattttcatc
     1561 tttttcaaat ttgcagatag ttcctttacc atcaacatga cctgttacta tatgaccacc
     1621 aaatcttgaa gaaagactca tagctctttc aagatttacc ttgtcatttg catttaataa
     1681 acctaaattt gtggaacgaa ttgtctccat cataacatcg gctgtaaatt cattttttcc
     1741 gaggtttgaa acagttagac aaactccatt tacggctata ctatctccaa gatttgtgcc
     1801 atctaatatt ttatttgata gtatggttac ttttccactc ttaccattag cagtaatttt
     1861 tctaagtatt ccaacttctt ctactatgcc agtaaacatc ctaacctcct atatgaatgt
     1921 attaacaaaa atttaattta aaacatctga ttctataaga atatcgccat ctatcaaagt
     1981 tacattattg attgttaact gtgttgaatc tgacaaatga tttattcctt ctccagaaac
     2041 gaatgtaggt gcatctttac cacctataat cttgggtgat agaaataatt tgaccttatc
     2101 aactaactta tttctaaaga gactgtcatt gagagtagca ccaccttcaa ctagaacaga
     2161 atcaatgttt aactctccta atttatacat tacaaactcc aaatctacta agttgttttt
     2221 tgaaggagaa attattgttt caacattatt ttcttttaac atagataatt ttatactttc
     2281 tttgcaacat gtgaaaacta tagttttact ggttttatct ttaaccaaat tactattaag
     2341 tggcaacttt aggtgtgtat ctattactat tcttgtagga tgagacactt tttcttgatt
     2401 gagcctacaa gttagtaaag gattatcgtt caaaactgta tttatgccaa ccattatact
     2461 ttggtattta tttctgtatt tatgagttag ataccttgat gattcattag atatccattt
     2521 tgattctagt gattttgtag caattttacc atctagactt actgctgatt ttacaataca
     2581 aagaggtctt ttgtttttta tatgataaaa aaatgcctca tttaaatctc ttgcttcatc
     2641 ttctaatatt cccacagtaa catcaatatt gttatctttt aattttttta ctccattacc
     2701 acaaacaagt ggatttgggt ctaatgtaga tattacaact ctcttaatct tattttgtat
     2761 aattttatct acacaaggag gcgttttccc ataatgagaa catggttcta agtttacata
     2821 aagagtagag tcttttagac tttgtttagc actgtttata gcatttactt cagcatgatt
     2881 agagccaaat ttctcatgat atcctttgcc tattatatta ctagctttaa caattacaca
     2941 cccaactaat ggatttggat ttacaaagcc ttctccattt ttagccaatt caatagcttt
     3001 tttcatataa taaatatctt tttctttttg attcacaaaa ttcacaatat gtacacctcc
     3061 tgtttaattg gataattttt aaacaaaaaa ccctgagaat taactcaggg tttagaataa
     3121 tctacaataa atgtttaata aatgtagaac aaaattgctc tacaaaaaca ctcattaaat
     3181 atcttcttcc atccagactt tactgtcggc tttggaattt aaccaaatca accaagtttt
     3241 accttggctc gcgggctata ccgccgattg ggaatttcac cctaccccga agattaagta
     3301 ttaaatttat atttagaatg tatcataaat tattttactt tgcaaactat ttttttaaaa
     3361 aatatatgtt aatatataat atagaatgtc tataaacttt gaaataccac gattgtgaat
     3421 ataaaaataa aaatttgaac ataatcagga aagaagtcta attaatttaa attaggagag
     3481 taatatatga ataaaaaact tttagaaata ctatcaaaat actatggata tacaagtttt
     3541 agaaaaggtc aagaatctat aataaactct atcttaagcg aaaaagatgt gttagctatt
     3601 atgccaacag gagggggaaa atcaatatgt tatcaaattc cagctttgat tttagatgga
     3661 atgacaatag taatttctcc acttatatca cttatgaaag accaagtaga tgccttaaag
     3721 actatgggaa ttagtgctgc ttttataaat agttcattaa gtagcaaaga atttaatgaa
     3781 atattaaata atattagaaa aaataattat aaaatactct atattgctcc agagagatta
     3841 gatgcacaag agtttattga gctaataaat aataacaatg taagtcaagt tgcgatagat
     3901 gaagcacatt gtgtatctca atgggggcat gattttaggt tgagttatag aaggatttct
     3961 gattttataa aaaatttgcc taaaagacct atagttacag catttactgc aacagcttca
     4021 gaagaggtaa gaactgatat aataaattta ctgtgtttag aaaatccaga ttattatata
     4081 actggatttg atagagagaa tttatcaata aatatagtaa aatcatctag taaaaataag
     4141 tatattttag attatattca aaatcataaa aatgagtctg gaattatata tgttgcaact
     4201 agaaaggaag ttgaaaatat atataatggt ttatctaaga gaaatatatc tgtgtcaaaa
     4261 tatcatgcag gtttatctaa aaatgaaaga agtaaaaatc aagaagattt tataaatgat
     4321 aatgtggata taatggtagc aacaaatgca tttggaatgg gtattgataa acctaatata
     4381 agatgggtta tacattacaa tatgcctcaa agtatagaaa actactatca agaaataggt
     4441 agagctggta gggatggaga aaaaagtgag tgtgtacttt tattttctcc aggagatgta
     4501 catatacaaa aatatttaat tgatattgga gttgaaaatc ctgaaagaaa attatttcag
     4561 cataagaagc ttcaatacat gattgactta gtttacagta attcatgcta tagaaagaca
     4621 atattgagtt attttggaga aaattatata gacaattgca ataattgtag caattgttta
     4681 gtagagggtg aaatagtaga taaaactata gatgcacaaa aagtcatttc atgtgtagct
     4741 agaatgaaaa gaagttatgg tgttactact attgtagatg tgcttagagg ttctaagaat
     4801 aaaaagattt tacagcttgg attaaatact ttgtctacat ataacattat gagagattat
     4861 tctagtgaag acttaaagaa ttttgtaaat acattggttt ctcatggttt tttagattta
     4921 gttgagactc taggcaatgg aaatagaggt agttttccta ctataagatt aaatgagatg
     4981 tctatgaaag ttttaaaagg tgaagtgaaa gtagagttta aagaaattgt tatgacaaaa
     5041 tcattggaag tagaggatga gttatataat gctttaagag aacttagaca ttcaattgca
     5101 agtgaagaaa ggatagctcc atatatggta tttggagatg gtacacttag agccatgtct
     5161 agtagttatc caattaataa agaagaaatg ctagatatct ctggagtagg agaaattaaa
     5221 tatcaaaaat atggtagaga ttttgaagca gtaattaaag aatatgtcga aaaaaataat
     5281 ataaataaaa aaatagatga aaaaaatgtc gattcaaaga acgttaatag tgatttctta
     5341 gaggttaata cagataaagt tttatatgaa aaactgttag tcattagaga agaatatgca
     5401 acaaaggaaa aattacctgc atatatgatt ttagccaata aggctttgaa agaaataagt
     5461 ggaagatatc cacttgatga agaacaatta aaagatattt ctggcatagg tggagtaaaa
     5521 tttgaaaaat atggagctag tattttggca gaggttaata aatatgtaaa agaaaataat
     5581 attaatgtta tttgggagaa aaagggcaaa aggaagttaa tattagatgg agaaagtaga
     5641 aaaaataatg aaatagcatt agatttgcta aatcaaggaa aagatataca aagtatcagt
     5701 caagaaatag aagtttcact gtcaaccatt attggatatg tgcatgacta tgtaaaggat
     5761 ggacatagta tatcatttga attaggacta gaaaattttt ataatgaaga taaaaagaag
     5821 atgattttag aagtttgcga aaaagttggc tatgataatt taaataacat aaaaagaaaa
     5881 cttccagatt caataaagta tgaaaatata agagctgtga tacttgactc ttatcttgaa
     5941 aacttaaaaa ataatattat agcagagtaa tttttaactt aataaaaaat aaaatttgta
     6001 ttattgtgtt gaactaataa ttttgctgtg ttatactgaa tttgtaaaaa taatgaaaaa
     6061 ttagagctag gggcgctaga attggctagc tgagagataa agccgtaact tacaaaccct
     6121 aataacctga tcaagataat gcttgcgaag ggaagctttt taatataatt ttattatata
     6181 aataggcaaa ttattcaatg ttaggagaaa tttgtctaag tgtatatacg attataagag
     6241 tgctttccaa acgaggaaaa gcactttttt tattttcaaa aactataact ttaatcttgg
     6301 aggattgtaa tatgaactat acaacacaaa tggatgctgc tagaaaaggc ataataacta
     6361 aagaaatgga aatcgtttct caaaaagaac aggtagatgt aaatgaatta agagaattaa
     6421 tagcaaatgg acaagttgtt ataccagcta ataaaaatca taaatcttta agtgcagaag
     6481 gtgtaggtaa aaatttaaga acaaaaataa atgtaaatct aggaatttca agagattgta
     6541 aggatataga aaaagaactt gaaaaagtta gagtagcaat agacatgaaa gctgaagcta
     6601 taatggattt aagtaattat ggcaaaacta gagaatttag agaaaaggtt gttgaaatgt
     6661 cacctgcaat gataggttca gtacctatgt atgatgcagt aggatatttg gaaaaagaat
     6721 taaaagatat aacagaagaa gagtttttaa atgtaataag acaacatgct attgatggag
     6781 tagactttat tactatacat gcaggtctta caagaagtgt ttgccaaaaa ataaaaaatc
     6841 atgagagatt gactcatata gtatctcgtg gaggttcttt attgtttgca tggatggaat
     6901 taaataataa ggaaaatcct atttatacta attttgataa aatattggat atatgtgaag
     6961 aatatgatgt tacattgagt ttaggagatg cttgtagacc aggttgtata aaagattcta
     7021 ctgatggtgt tcaaattcaa gaacttgtag tattaggtga acttactaaa agagcatggg
     7081 aaagaaatgt acaagtaatg atagaaggtc ctggacacat ggctattgat gaaatagaag
     7141 caaatgtagt attagaaaag agattatgcc atggagcacc tttttatgtt cttggaccat
     7201 tggttacaga tatagcacca ggttatgacc atataacaag tgcaatagga ggagctttag
     7261 catgtgccaa aggagtagat tttttatgtt atgtaactcc agcagaacat ttaagattgc
     7321 ctaatttaga tgatatgaaa gagggtataa tagctgcaaa gatagctgct catgcaggag
     7381 atatagctaa aaatgttaaa ggtgctcgtg aatgggataa taagatgagt aaagctagag
     7441 ctgatttaga ctggtgtgag atgtttagac ttgcaataga ccctgaaaaa gctaagagat
     7501 acagagatga atcaactcct actcatgagg atagttgtac tatgtgtgga aaaatgtgct
     7561 caatgagaac agttaagaaa atattaaaca atgaggaact taatctaata taatttttgg
     7621 ctagtatgac tggaataaaa ataagctgaa aagaggaggt gatttagtga aggttaatgg
     7681 gaaggaaatt gaatttgaaa aagatttgac tgttatagat ttattaaata aatataattt
     7741 aaaaagtgat agagttgtag ttgaagtgaa tttagagata attgaagaat ctaactacaa
     7801 tacatatgta ttaaaagacg aggacattgt agagcttatt agctttattg gaggtggtta
     7861 aaataaaaat atttgtaaat gaattattaa cagatgttga ggaaaataca actgcttata
     7921 aagttagaga tagctataac aataaatgtg atgtattggt gttaaatgga tatccaatta
     7981 aaacagatat gaccctttgt gaaaatgata aattaacact tatacaaaaa ggagttaagc
     8041 catcacttga tgaattggaa agcttgttga ttgctagaca tactccaaat atacataata
     8101 aattaaaaaa agggaaagtt gctatattgg gattgggggg acttggttcc aatatagcta
     8161 tctctttagc tagaatagga gtgggagaac ttttacttat agattatgat gttgtagaac
     8221 catctaattt aaatagacag cagtatttta tagatgatat aggaaaacta aaaactgatg
     8281 ccatgataga aaatataaaa aaaataaatc catttataaa attaaataaa cgagatattt
     8341 ttttaaacaa gaacaatatg gatactatta aggattcaga tttaataatt gaggcctttg
     8401 atgatgcttc atgtaaagca caggtatgta attatgtatt aataaattta aaagataaat
     8461 atttaatagc atcatctggt atggcaggtt actatgattc aaatataata actactaaga
     8521 agataaaaga caggttttat atatgtgggg attttgtgaa tgaagctaaa tttggtgaag
     8581 ggcttatggc tccaagggtt gccatctgcg caaatcatat ggcaaatttg gcaacgcaaa
     8641 tacttataga tatgtaaata ttaaaattag atataaaaaa gattgaatat taaaaaaatt
     8701 taacgtggag ggaaataata tggataaatt ggtacttggt ggacatgaat ttaatagcag
     8761 attattggtt ggaacaggta aatatggttc aaataatata ttgcctgagg taataaaaga
     8821 aagtggaagt gaaataataa caatggcact tagaagagtg gatttagaca ataaacaaga
     8881 aaacatatta acgtacattc caaaagagat gacaatactt ccaaatacat caggagctac
     8941 taatgcagaa gaagctgtaa gaatagctag aatatctaga aaaatgggat gtggagattt
     9001 tataaaaata gaagtaatat cagatactag atatttactt cctgataatg aagaaactat
     9061 aaaagctaca aagatacttg ctgatgaggg gtttatagtt cttccatata tgacaccaga
     9121 cctttatgct ggaagaagac ttatagaagc taatgcagcg gcagttatgc cacttggagc
     9181 tccaattggt tcaaatagag gtcttcaaat gaaagaaatg ataagaataa tgatagatga
     9241 gttggatata ccaataatag tagatgcagg tattggaaaa ccatctcaag ctatggaggc
     9301 tatggaaatg ggagctgatg cagtacttgt caacactgct atagcttcag caggagaccc
     9361 tgtacaaatg gctagagcat ttaaattagc tgtagaaggt ggaagagaag catatattgc
     9421 aaaaacagga aatgtgtcag aatttgcaaa tgcatcttct cctttaacag gttttttagg
     9481 caatttatag aaagtggtga ttggtgatga gtttttatga tgtaatagaa aaatataggg
     9541 attttgattt tgatggatat ttaaataatg ttactgataa tgatgtttta agaagtttat
     9601 caaaagacaa gcttgaagat tttgatatat taaatttgct ttctaaaact gcagtaaaac
     9661 atttagaaga tatggcacaa aaagcacata aattaagtgt tcaatacttt ggtaaaacag
     9721 tatgtttata tacaccaatg tatatagcaa attattgtgt taatcaatgt gtttattgta
     9781 gctataatat aaagagtgga ataaaaagaa aaaaattaac tatggatgaa attagagaag
     9841 agggagaagc aatttcaaaa gaaggtttca aacatctact tgttttgact ggagaaagta
     9901 gttttcactc aagtgtagaa tatataggtg aggctataga aatattaaga gagaaatttc
     9961 cctctatagg tatagaagtt tatccaatgg aagtagaaga atataagtac attgtagata
    10021 aaggtgttga aggattaaca gtatatcaag aaacttatga cgaggaaata tataagagag
    10081 tacatataaa aggcccaaaa tcaaattata aatttagact agatgctcct gaaagagggg
    10141 caaaagcagg tatgaggact ttatcaatag gtgcactttt agggctaaat gattttagaa
    10201 aagaaacttt ttttacaata ttgcatggga aatacttaaa aacgaaatat cctcacattg
    10261 agctttcata ttcaacacca agaatgagac cttttaaagg gtgttttgag gaattggtag
    10321 atataagtga tactgattta gttcaagcta tggtatgtat gagattattt gaccctcatg
    10381 cagctataaa catatccact agagaaaatt tagaaatgag aagtcatata atacctttag
    10441 gagtaactaa attgagtgca ggtgtatcta ctgatgtagg aggtcattct caagatgagc
    10501 atgatactgc tcaatttaag ataaatgatg aaagtactgt taaagatgtg gagaaaatgc
    10561 taaactcaat tggttatcag catgtgttta aagattggga aagattttaa atgtatctga
    10621 taacaaacag aaaattatgt agtgaggaac gatatttaga agttattaaa gagtctatat
    10681 tgagtggtgt agaaaatata ataataagag aaaaggattt ggaatatcaa gagctaagaa
    10741 aattatatat gaaaataaaa actaaaatca attgtataga ttttcaagag caaatatcag
    10801 atgaaagttt gaaaactaat ataaatcaaa aagagtgtag aaataaattc aaggttaatt
    10861 ttataataaa tagtaacatt gaattttttg aaaaagtgga ttgtcaaggt atccatcttc
    10921 cttttaaatt attcttgaat ttaattgaaa ataagtataa ttttaatgaa aataaaatac
    10981 taggattatc tttacataaa gtagaggaag tagattattt agaaaaatta ataagaaatc
    11041 aaaatataaa aatagattac ataacattat cacatatata tgaaactaaa tgtaaagaag
    11101 gattaaatcc aaaaggaatt gagcttttaa aagaagctaa aaagattact gatattaaaa
    11161 taattgcact tgggggaatt ttaccatcta atgtcaagga aacattaaaa tactgtgatg
    11221 attttgctat aatgtcaact ataatgaggt ctaaagatat taaaaaaacc atatcaaatt
    11281 ataatgaaaa gttgaattag taaatatagt atattgaatt tttaacttaa ataaaaataa
    11341 aaaagttatc ttttaaattt taaaaggtag cttttttatt ttatatcttt gctaataaaa
    11401 aattgtaaaa agggaaaact ttagtcagag agattaaaca atatcctaga aagatttaaa
    11461 atttagtaaa gtatggagga cattataatg actgacagta aaaagaaacg atttattata
    11521 ccacacactt ttacaataat atttttacta atagtcttaa tggcaatatt gacttggata
    11581 gtaccaagtg gtgaatttag tagagaagat gtagaaggta gaatggtagt tgtaccaggg
    11641 acttatcaaa gtgtagaaag taatcctcaa ggatttgcag atgtttttaa agcaccaata
    11701 gaaggcttta tcgattcagc tgaagttgta ggttttgttt taatagttgg aggtgctttt
    11761 ggtattgtaa ataggactgg agctatagaa gcaggaatag cttcggttat ctctaagttt
    11821 aagggaaaag aacttcttat aattccaata tcaatgattt tatttggact tggaggtaca
    11881 acatttggga tggcagaaga gacattacca ttttatatga tatttgttcc actcatgaca
    11941 tccttgggat atgattctct aacagcaata gcaattgtat ttataggagc agcagcagga
    12001 gccgccgctt caacaataaa tccattttca gttggtattg cacaggcact agctcaactt
    12061 gctcctggtt caggagtaac ttacagagta gttattttta tagcatatat actaataagt
    12121 atagcatttg ttatgtacta tgctaagaag gtaaaggaaa atcctgaaag ttcaatagta
    12181 tatgaaatag ataaaaataa taaatcaata cttaatcaaa cttcaacaga aataaaagaa
    12241 tttactttta aagaagtatc tgttcttgct atatttggaa tagggatggc aataatgatt
    12301 tggggtgttt taagtcaagg atggtacatt ccagaaatat caatgtgttt tgctgcaata
    12361 ggtgtgcttt ctggattggt tggtagatta tctcaaattg aaatctcaga aagttttata
    12421 gatggagcaa aagatttagc atctgcagct cttgctatag ctttggctcg tggaatcgta
    12481 ataattgctc aaaatggatt tataatagat actatattaa attccgcagc agcctttcta
    12541 ggtgggcttc caaaggttat atttgtatat ttatcatttt tcttggaagc tgcattggca
    12601 tttttaattc catcatcttc aggtcttgct tcacttacag tacctgtact tgctcctctt
    12661 ggtgatttgg ttaatatatc ggctcaagtg atagtaaccg cttatcaatt tggtgtgggt
    12721 cttacaaact ttataactcc aacttcagga gtactgatgg gagcacttgc agtagcccat
    12781 attccatttt caaaatgggt aagatttata atgcctatct tgttgatttt gacagctgta
    12841 tctctagttt ttttaacaat aggtatttat atagggtttt aattaagtgt agttttattt
    12901 aagatattta gtaatggtat aaaatgataa tatgttttca ataaattgcc actaatttaa
    12961 ttagtggtaa tttgtttttt gtatttaaaa ataaatgtat ttacttgtat tttgaattaa
    13021 tatctactta gacattgttt taattgttat attttcattt aattaagcat tgatttatca
    13081 ttttttatat ttcatataac aatgcaaaaa ataattttta tatagtaaat gacaaaagtt
    13141 tacaataaat gtatattttc ttactcattc cttaaaatta ctcatttagt ttaataactc
    13201 tcatttcata tgtaaagttg gtaaaaaaat taaaattaaa agtaaaaaac taaataaatt
    13261 aatgttaatt tgaaatatat atgaaggttt ttggagaata cttacttatg ataggaaaaa
    13321 atgttaaaat aatagtgtaa tcaaatataa aggactgaaa taattaacag ttattaaata
    13381 ttaggagtgt aaaaatttat gggattaaaa gaatttgatt ttattgaaga gtctattgat
    13441 atgttgagga caatgtcacc aacattagaa actatatcag atgaaataga agagtatttt
    13501 gaaaatatct tggatgaaaa gaatcaagaa tatataaatg taacctctag aataaaatca
    13561 gaatcaagtt taagagaaaa gataattaga aatagatatt taaaaaaata tggagaagca
    13621 agtaatctta ttcataatgt ttctgactta ataggcctaa gaattgagtg tagatttatt
    13681 gaggatgaaa acaaaatata tagacttttg agaagatatt ttaataaaac agatgacaaa
    13741 ataaactatt ataataaaga gaataagaat attaaattaa aactatctga gagacaaccc
    13801 aataagcaaa aaaatggatt tgaaatatat aaaatagatg gagtttttgc gtatttagat
    13861 agagaagtaa aatttgaact tcaaattaaa tctcttgtaa atgtgttttg gagtgaaata
    13921 gaacataaaa taatttataa aaacaataca tatttacttg ctgataaatt tataaaggat
    13981 atgatggact ctataaagaa taatcttact atgatagata atcagctttt aagtatttat
    14041 aaaaactttc attcagggaa gtcttttaat atgaaagtaa gtaaaaaaga aattgaaaaa
    14101 ttatttgcga aattagtcta tgacgctttt tctgaaaaga tgaataaaag tataggtttt
    14161 gttgtagatt ttaaaaaacc atgtgagact atattgaact attcttttaa taaacaagat
    14221 ataagtgatg aagttttagg taattttatg cttgatgagt ttgcaagatt aaatgaaatt
    14281 gtaaacaagg atatagattt taatgagcaa atagaatttg aaagagaacc aacatttgat
    14341 gataagtttt gtaaagacct aggaaatcat tttagaagta gattaaacac agaatttcca
    14401 tggaacctat tttttagaat attatttgaa atagagccat ataacaatac caaagacttt
    14461 gaaaactttg tagagtttat aaaagaaaat gtgctactag aagaaaatag ggagcaatta
    14521 ttatgccaat ttgaagagga tagtaagctt ataattgaag atatatatga ttgtatattt
    14581 aatagtataa gtgagattga tagtgttgaa attttatata actataatct tgaaaaaata
    14641 aactttacat caagtgaaat cataaattgt atatgtagag aatatgagtg ttatggtgaa
    14701 tacttagaag aaaaagaaaa gcttatgaat acatttaaag aaaagattat tcaaatcttt
    14761 gagtaatagg ttaatgctga agtggcgcta atgcgccatt tttcaaatat atatgaatta
    14821 agtaaaatta ttttggagga ggcgatttgt atagagaaaa caggtgtaat tttggcaggg
    14881 ggaagaaatt ctagaatggg tagagataaa gcctttttag agttacatga taagcttttt
    14941 attgaaattg caatagaagc atttaaaaac tttgatgagt tgataataat atctaataat
    15001 gaagaattat attctaaata cgatattaaa gtttataatg atatagtaaa agatgttggt
    15061 ccaattggag gaatatatac tgctcttgaa tatgcaaagt atgatatagt tacaattgca
    15121 tgtgatatgc catatctaaa taatcaaata gtcgaaagaa tagctaataa aatgaatgat
    15181 aaaagtgtga tttcagtgac aaatggaaag ttacaaccat tgtgttctgg atataaaaag
    15241 agtataataa ataaagtatc tttatgtata agggaaaatg atttaaagct cagaagcttt
    15301 atagataaaa tagataaaag ttatatatac tttgatgaag aagatttatt tttaaatgta
    15361 aacactgttg atgagtataa aaaattaact aaagtttaat tagctatggt tgtaaaatag
    15421 agtaggattt atatggagga gagtttatga atttacttaa atgcgattct tgggcagtaa
    15481 tattaaataa tagcgataaa gaaagtaaag catataaaat attagatgaa cttaaaagga
    15541 atatgtacaa agttgttgct atagatgaag agaaaaaacc tattgaagga atagatgtgt
    15601 atgaatgttt aaaagatgtt ccacacaata ttgatgttgt agctattatt gataaacaat
    15661 ctaagatgga tgtgatttta gaagaagtag agcttttgga tatacaaaat atgtggtttg
    15721 aaaaaggaag ctttagtgaa atgatgatta aaaagactaa agatttaaaa ttaaatatag
    15781 aatataattt aagtttatat gatga
//
LOCUS       DAEPXW010000090        15655 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.091, whole genome shotgun sequence.
ACCESSION   DAEPXW010000090 DAEPXW010000000
VERSION     DAEPXW010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15655
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.091"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(269..580)
                     /locus_tag="KRM55_002855"
     CDS             complement(269..580)
                     /locus_tag="KRM55_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595072.1"
                     /translation="MKKIIKSFTFCFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(636..1229)
                     /locus_tag="KRM55_002856"
     CDS             complement(636..1229)
                     /locus_tag="KRM55_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1595073.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            2080..2730
                     /locus_tag="KRM55_002857"
     CDS             2080..2730
                     /locus_tag="KRM55_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH1595074.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            2944..3615
                     /locus_tag="KRM55_002858"
     CDS             2944..3615
                     /locus_tag="KRM55_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595075.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            3612..4742
                     /locus_tag="KRM55_002859"
     CDS             3612..4742
                     /locus_tag="KRM55_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595076.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            5186..6031
                     /locus_tag="KRM55_002860"
     CDS             5186..6031
                     /locus_tag="KRM55_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595077.1"
                     /translation="MIKVGELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            6031..7059
                     /locus_tag="KRM55_002861"
     CDS             6031..7059
                     /locus_tag="KRM55_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595078.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDDYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            7062..8075
                     /locus_tag="KRM55_002862"
     CDS             7062..8075
                     /locus_tag="KRM55_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595079.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(8592..9842)
                     /gene="cme"
                     /locus_tag="KRM55_002863"
     CDS             complement(8592..9842)
                     /gene="cme"
                     /locus_tag="KRM55_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBH1595080.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVSAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(9928..10674)
                     /locus_tag="KRM55_002864"
     CDS             complement(9928..10674)
                     /locus_tag="KRM55_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1595081.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(10808..11830)
                     /locus_tag="KRM55_002865"
     CDS             complement(10808..11830)
                     /locus_tag="KRM55_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBH1595082.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(11830..14250)
                     /locus_tag="KRM55_002866"
     CDS             complement(11830..14250)
                     /locus_tag="KRM55_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1595083.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPISDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSNKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLSAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVYFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPNLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKALKENP
                     KSITGRYL"
     gene            complement(14336..15256)
                     /locus_tag="KRM55_002867"
     CDS             complement(14336..15256)
                     /locus_tag="KRM55_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1595084.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
BASE COUNT         5570 a         2023 c         2408 g         5654 t
ORIGIN      
        1 ctaatctaaa gaagtatagt aaactaattt aggaagtata gaaaattaat ctaaagaagt
       61 ataataaact aatttaagaa atatagaaaa ttaatttaaa gaaatacaat acattaattt
      121 ttaagtaaca ttaaattaat gtaagtaaaa taatgttcat atgaagattt aaaggtgcat
      181 tttctgaagc taagtatatg ttgtagagtg ttatgtctct ctatcctgtg aagtttaata
      241 gctcaagaaa atgcactatt tatgatgatt attttgtttt atttccaatt ttggaaataa
      301 ctattctaat taaatctaaa attataccat aaataagaaa agaaagtata gatgctatgt
      361 accaataaat cgaaattgac cctgtaattg ttctacatgg gatttgcata cctgaatcca
      421 taaaaacaaa aaaactatca actctggaaa taatagacaa aataggattt aaacctatta
      481 gaacaatact ttttgagtct tgaccaattt gatgcatata aatctcaaat aatgcaatta
      541 aaaaaaaaca aaatgtaaaa gatttaataa tttttttcat caaaatacct cacataatat
      601 aaattctgtt tgcactattt gcttactaca actatttatc tccattcagt cacatcactt
      661 aattgtaatc taggtcttct tgatggttct tcatcaggat aacccaaaga tattgctgcc
      721 actaattgac tatctgtatt taaccattca cataattcac gatatgcaaa gtatacatca
      781 caaatccaaa gactacctag acctaattcc acagctgtaa gcgacatatt ctgaattgca
      841 gctccaattg attgcatgtt tgccatttca tagaatcgtt cttcagggga tagcttttct
      901 aaaggtgatt tacctaatat atttaaaata aaaattgtta ctggagcttg tttcatgatt
      961 tcaactgtgt aatttgcacc agcgatatgt tgacgacttc ctggaagaag cccattatca
     1021 ttaatttcat tttgaatacc tttgctcatg gctttaagca tagattcttt ttccttttca
     1081 gtgatgacaa caaaacgcca tggttgcctg tttttagatg aaggtgcatt tattccagct
     1141 tcaattattt tctctatagt ttcatgtgaa atgctttgat ttttatattt tctgatactt
     1201 cgtctttttg atatagaatc acttatcatt ttaagtaacc tccgtttatt ttttggaaaa
     1261 atctatttaa tttttatttt ctattttaat tattttagca ttaatcagaa aaaaagtcat
     1321 tgattttagt atacaattat taatgattat attaagaatt gtatcaaaaa gtatgtgatt
     1381 atactaaggg attatattaa acattatatt taaaattgta tgaaaggttg tatttaatat
     1441 tatattgaga gatatatata ttaggattta tatatattca gatttattat tatattgagt
     1501 cttatattaa attaaggact ataatttgaa aataagctat aaaaacttaa tattgttttg
     1561 ttcagagata aaaaaagaat actttaggtg atttttatta aaaattaaga gtgataaaat
     1621 tatatacttt ataaatgtaa atatgacgaa taaaaatgat aaatataata atatatatat
     1681 ttacattagg agttttctat actataatta tttaaaacta aatataaatg ttggaattat
     1741 ttaggacttg aaattgtcta aaaataaata taagtgatga agaggtgatg tgatgagatt
     1801 agatatggat agtatgttat atgtactaat ttatatgaca ttattggtat ctatcattgg
     1861 aagtatattt tatttttgta aagacctctt aaatcataaa attaagtatg ttttaataag
     1921 agacatattt gtaaatagaa ttacatattc tgaagaacgg ttgcctaaac agtatatagt
     1981 ttttcagaaa tatgatattt ggaggtattg tagtttgttt taatttgaaa tgaatctatt
     2041 ataaattcta aagtttaaaa ataaaaagga gagaataaaa tggatttcat ttcaagtata
     2101 ttgcaaggat tattaagtat attatttaat tttacaggtg attttggaat ttctattgta
     2161 cttataactt taatagttaa attagtactt atgccactat cattaaaaca aagattttct
     2221 gtaaaaaaac agcaagaatt agctgaaaaa atggaacata taaaagaaaa gtataagaat
     2281 gatactaaag aattggaaaa gcaaatacaa gtaagttctg tagaaagtat gaagagtatg
     2341 ctgggatgtc ttatagtttt ggttcaaatg ccagtagtat atgctttata tcatgtatgt
     2401 ttagatatga caaaggaatt tacaacaatt ataattccat ggattgctaa tttaggtaca
     2461 tttgataatt tgtttatatt accttgtata tatacattaa ttatgttagc ttcaaattta
     2521 gtgaattata taccatattt aaaaataaat tctcaagtaa agtttaacaa acaaatggct
     2581 gtggtgacta ccataacaag tcttatacta actgttagaa ctccagtagc cataggtctg
     2641 tactttataa caagtgcaat ttattcatta attgaagata tttgttttag aatatatttt
     2701 aatcgaaaaa atagaatagt gacaaaataa tataattatt attagaaata ttttagcctg
     2761 ctaacataga aaaagttagt aggctatttt tatctatgat atcaattcca ttaagaatag
     2821 tctaaaaaat actatcaaaa tgctataaaa aatactatca aaatactata aaaaaatagt
     2881 tgaaaaataa ataaattaat ataaactaaa ataaagccta caaaaaagag gtgataaata
     2941 gaaatggcta aaatactaat tgtagaagat gaaaaaagaa tgcaaagtat tattgtagaa
     3001 tatatgcaaa agggaggata tacttgtata actgctgatg atggagtcga ggcacttaca
     3061 atattaaaga gcaacaatat agatttaatg atattggata ttatgatgcc gtatttagat
     3121 ggattttcag tgtgtagagt ttcacgtgaa atgactaata tacctattat tatattgaca
     3181 gctaaaggtg aagaggagga taaattaaag ggttatgaat atggcgcaga tgattatata
     3241 acaaaaccat ttagccccaa agtactttta gcaaaagtta atgccttgtt acgtagatat
     3301 actactgata ttcccaaaaa ttcattgagt ttaggaaaga tttttattat ggtagcatca
     3361 aggcaagtgt atgtagaaga taaattgatt gatttaacat ataaagaatt tgaattattg
     3421 cgtttattta tggaaaaccc taatcaagtt ttttccagag agaaactttt aaattgtata
     3481 tggggatatg attttgaagg aaacacacga actgtagata cacatataaa aaccttacgt
     3541 aaaaagcttg gtagtgaagg acaccatata gttacattaa ttcgttcagg atataagttt
     3601 gaggttaagg aatgaatagt ttaagaaaga ttatagaaaa actgaaaaat gtagatattt
     3661 caaattggat taaacaaaat tttggactat attcagttag aaaaaaagtg tttttacttt
     3721 ctaaattatc aggagcgtta attatattat tttatctggt tgttgaagaa ttttcgataa
     3781 actctaaatt tgaattttgg atttggttta taatactggt tatatttatt atgagtattg
     3841 atttcttatt gggaaaattt atttcagaac caatcacatc tataaataaa tctgcaaaaa
     3901 gtatgtccca acttgatttt tctaatccat gtactgtaaa tactaatgat gaatttggag
     3961 aactttctag gagcctgaat acaatgtcta caaatctaca acaggcatta tcagacctag
     4021 aaagtgcaaa tattcaactt gaaaaggatg taaataagga aagaatgcta ttggaacaaa
     4081 gaaaggagtt ggtagataca atttcacatg aaatgaagac tccacttggc attatacgtg
     4141 cgtatacaga ggggcttatg gatgaagttg atgaagaaaa aaagaaaaat tatatgaatg
     4201 ttataataga agaaactgat agaatgaaca atatgattgt atcattatta gacttatctg
     4261 cattggaagc aggagtttct aaacttaacc cagagcgttt tgattttata gagtttgttg
     4321 aaactgtggc aggtcgtctt ttaattgata taccagatgc caatttttat tttacatatg
     4381 atttgccaga gtatgaagtt tttgtagtgg cagataaaat gagaatggaa caagtagtag
     4441 agaatctagt tattaatgca aagaagcatg ttgtatataa tggtaattta gatttatcga
     4501 ttacatgtga aaatggcttg cttttatttg aaatttataa tgatggtagg tttatagagc
     4561 aagatgagat ttcaaagatt tggtctaagt tttatcgtag tgttcaatct cagcgtacag
     4621 gaggttcagg tctagggctt gcaattgttt cacaaatact tacaatgcaa gggttagaat
     4681 atggagtgaa taatcgtgat agaggagtag agttttattt tatgattcca attgatgaat
     4741 aatttagtat taatttataa attataagta tctgatgtaa aatatttttc tttgtatatg
     4801 taagcattta aagagaataa aataaaaaaa cttaatgaaa aaagcttaat gaaaaagtct
     4861 aataaaaagt ttaataaaaa gcttaatgaa aagcttaata aaaagtcttg ttttcctgat
     4921 gaaaacaaga ttttttatta agctttttat tatttcactt cgatttcaca agagagacac
     4981 tctgatttca ccaaatagaa ataaaatagg ttaaataaat taaaaaatag aagcgtaatt
     5041 aaataaggtt acaaggggga gtacttatga aatggtatac atggttgact attatattga
     5101 taatattgct ttctattccg cttaaaatta aatttataaa atggtgggat agacgacaaa
     5161 aaaatgataa aggaggttat gatagatgat aaaagtagga gagttaaaat tttcttatgg
     5221 aaaagataaa cagatattgc atggacttaa ttttgaagta aaagaaggag aaatctttgg
     5281 attccttgga cctaatggtt caggaaaatc tacaacacag aaaatcttaa atggtgtttt
     5341 aaaaggttac aatgggcacg tatccatttt tgggaaggaa gttaaagcat atacagagtc
     5401 tctatatcaa aaaattggtg ttttatttga atttccttat ttatatacca atttaagtgc
     5461 aattgataat ttagaatatt tttcgtcctt ttatcctaaa aatcaaagga gagacatata
     5521 tgaactctta gatttgttag agtttaagaa agagtttata aataagcctg tatcatccta
     5581 ctcaaaaggt atgaagcaac gtattagcat ggcaagagca ttggtaagta atccaaagtt
     5641 gttattttta gatgagccta ctagtggact tgacccatct ggagctgtac tatttcgtaa
     5701 gattattgaa gaagaacgaa aaaaaggaac aactatcttt ttgactactc ataatatgct
     5761 agatgcagat ttaatgtgta acaatgtggc ttttattgca gatggaaaga ttatggtaat
     5821 agataaaccc aaaaatttaa aaatgaaaaa tagcaataat aaagttgaag tggaatttgt
     5881 atataatgga aatcgagata ttgaaattgt agatatacaa gagttagaat ctggaataac
     5941 ttttaaatat gatgaaatct taagtgtaca ttcaaaagaa cctacactag aagaagtttt
     6001 tattaaatac acaggaagga tgttagtgta atgtattcta aattttttac cttagtaaaa
     6061 aaagattttt ggatgatgat ttatggtaaa ttttttgtgc tgacacttgg ctctctcata
     6121 ctttattcgt gttatattaa ttttggttat gtaaagttta tggatgaaga tagttatcac
     6181 aataatgtat atctatataa tccagagaat ataagcatga gtgcatctcc attaattaat
     6241 caagtttctt ctataggtga attaaaagca aaacttgatg aagatacaag tgcagtttgt
     6301 attgatatga gttccagtaa gccgaaagta attttacatg aaagtattaa aggagttgac
     6361 gattatagag ctgactatgc attgtcatta ttatcatcag aaaaagacca taatagcaaa
     6421 atatcagaca acaatgcaat aattcaaatt aatgataagg atacatctga gataaaacaa
     6481 agaaaagaca tgacttgtga gattttattc tttgaaattg tagctattgg atttttaggg
     6541 attgcctctt tattatttaa agaaaagcag atgggagtaa tgcgtattac tggtatttta
     6601 cctgtaaaaa gaagtctttt tatattatca aagatatttg ctttttttat atgtgaccta
     6661 tgttttacag ttcttttagt agtatttaat attggatttt tagaaggaat aaaaatactt
     6721 ccacaagtat tagttcaagc tagtatttta tcaattatta tgtctttgat tggaatagga
     6781 tgctcaatgt tattgagaga ttttaagcaa ttttctctta tatatcttgt ggttgctgta
     6841 ttcataacta cacctatatt tctatctgca aatacatctt ttgaaataga ttggattaaa
     6901 tatcatccct tctatcatgt ttatagtcag cttaaaaatg cgtttttcat gaatttttca
     6961 aaagaattag tttattttgt agtgtgttct ttgacaataa tagttctatt tttacttgta
     7021 aaatatattt ttaataaaga gttggttagg gagggataat cttgatagga ttacgttacc
     7081 agttaaagag tataaaaaaa gataaaatgt gtataatttc cttcttttta ccagttgtta
     7141 tggcgatttt aataaatttt atgggaacaa ttgatatatc ttcattagga gagatacgtt
     7201 ttggtatagt gaaggataca cttcctgtac aaacagagca gtggttgaag aagtatggta
     7261 tggtaagtgt atatgacaca aaaatgcatt taatacgtga aattaaggat attaaaacgg
     7321 acacaattgg agttgttaga gatggtaaag ggataaaaac tgtgctttat ggaaatgaga
     7381 ttaatgctat aaaaaatgtt ggaaagacat tgccagagat gtttagacta aagggtgatt
     7441 taaaagatgt tgaggttaca atattgccta aagatagtat tttaaaagag tttcaaaatg
     7501 tttttattgc catgatttta attactgcta tgtttatggg atgcaccttt aatgcaatga
     7561 atattatatc tgaaaaagaa gatggaatat catttataaa tgaagttttg ccacagagta
     7621 gaagtcagta tattatacaa aaagtatttt tgggtctttt atgtgggtgt ttatcttcaa
     7681 tgataactgt atttatatgt ttggatattt caatattaga tatgataatg atgttgttac
     7741 tcgttgtatt ttcagcattt atttcatcac ttataggttt atttattgga aagttgtcag
     7801 aaggtcttat ggtaggaatt gtttatatta aaatagtaat gattttattt ataggtactc
     7861 ctttgttaat atatcttcta ggggttaata ccagcggtat agggaattta tgctatataa
     7921 tgccatcagt tgctacattt aatggtatta tggagattat taatggtaat gtcattatta
     7981 taaaagatat tgtaattttg gctgtacatt gtgtagtatg gtttatgata tatattattt
     8041 tagataaaaa aagaaagtta tcttttagta gataactcag tataattata attgggacaa
     8101 tttaataggt gatttaatat actttgtata gtgtaattta tgtagtgcaa tttgtatact
     8161 ttaatttatg tagtgtaata gttagtttta ttttataatt attcaatata atttagtaag
     8221 aagttcagta caattagagc tacttagtgg aaaacttaat aggtacttaa actatataaa
     8281 tactttattt tcctccattt gtactataaa tttaatttat gatataaatg gaggtattat
     8341 tatatgattt gataaatttc atcattataa cctacaagta aaggtattat tatataaagt
     8401 taataaagat agtatcaaaa tattatttgc tataaagaga gggactcaaa ataaagataa
     8461 acctattttt caatgttgaa atgataaaat atatttgatt tcatataaaa aattttcttc
     8521 ataaattaaa aagtccattt taagccccct catttttaac cagataaatc gagttaaact
     8581 atttaaatat attactcgga ttcatttgac ttagatattc cttgcttgta aaattgtttt
     8641 gaatagggga tagccaaagc aaaaaataaa agtataatcc ctgctatgat tattaaatta
     8701 ttaatagaaa ttacatctgc cattggtccg aaaatcatca taccaagagg aataaaacca
     8761 gtatatataa taataggtaa gctaagaact cgacctagca tttgtggtgc tacatgctct
     8821 tgcaacatag tcatagctga tgcttgaata attggaattg aaaaattcgt aaaaaacata
     8881 aatataaaaa attgccaagc ttgtgttaca agacctagaa taattgaaaa aatagcatag
     8941 gataatattg ctagaaaaaa ggtcttattt ctatttttaa aaccaccaaa aactcctata
     9001 atcaatccac ctaaaaccat acctaaaaat ccaatcattt caataataga caggtatata
     9061 taacccttgc caaatgttcg ttcaataaga agtcctataa gaaatcctga tggaacacaa
     9121 agaagcatga atgctccata agtaaaaagc acttttctaa tgaacttatc tgaaaaacag
     9181 tactttatcc ctgataccat atctgcaaaa aatgagactt tttcagtttg ttttggtata
     9241 tcatgtttag gaattttgat gaatatcaat aatacaatag caataattgc agtaaataca
     9301 tcaattaaaa gaacttgatt tattttatta ccaaatccaa gtattgcagc agctacaata
     9361 ggaactataa attgtactat agactgtagg ctactattta taccattaaa acgcattaaa
     9421 tgttcttctg gtacaagttg aggaatcatt gcgcttacag caggtgtttg tacaccactt
     9481 cctagtgaac gtataacaga tattactgat atggctatta attcacttgt tgtgccattt
     9541 gatgacatca taaatagaat tagaactaat gtagatatag caattgttga atctgataca
     9601 attatgagta cctttcgatt gtagtagtct gcccatacac cagcaaaaaa agaaattatc
     9661 atttgaggta taaaggagca tacagttaaa actgttaccc atacacctga tgatgtctga
     9721 agtgtgacat accatatcat tgccatttgt acaagtgatg agccaaataa ggaaatatat
     9781 tgacttgcta aaaaaagaat gacttttttc ttccatgtag aattagtatt tttgttttcc
     9841 atcctattcc tcctttgatt tgtgtgttga atttttcttg ctcttaagga taacacacaa
     9901 atcaaagtct ggagttagag tggagggcta ggaaaattgt tttttcataa tttgaagatg
     9961 agatttcatg gtttttgcat tatgttcagc ttctttcaat gaagttatca gtttgtcaca
    10021 cactgagata atttcgtcat catcttttgg agtgtcaagg acagttttaa tattagtatt
    10081 aggattagaa gataaagcat ttaacattcg taaaatagct gaaagagaat agtttgcaca
    10141 acgaagtgcg cttataattt taagtcgttt tatatcttca tcagtatata cacgataacc
    10201 attttgtttt ctttttactt ttaacaaacc attcatttcc caatttctta aagtatctat
    10261 tgtaacgttt aagtgttctg cagtttcttt tctagttaaa aagagtttat ttgtttctgg
    10321 agtatttcca tttaaaatct gtgcaacaat agtaagtgct tcctcggcat tagatttttc
    10381 tatttctaat tgttgcaagt attgatttac aagactaata gccttatcaa agtccctatt
    10441 cgctgatgtt cttacaatct caagggcatc ttttcttaat cccctttgta ccacttcaat
    10501 tttcaaggct gtacgagcaa atctaaattg ttctatatga aaatcattaa agatacgata
    10561 accattggta ttacgcttag gtttaggtat taagtttagt tcttcatata aacgtactgt
    10621 attaggatgt acaccaatta aatctgctac ctctgatgtc gtgtaagtgt ccattagtat
    10681 tcaactcctt ttagatatat agtattagtc ataataacac caaacaaaag tctggtgtta
    10741 taatggaggg tttggctatc taagagtaat tagtttatga aagagtaatt aatttatgaa
    10801 agagtaatta atctattata gaagtaagta tatatttttc aataaactcc catctatcac
    10861 gaggtttaaa cactatttta gatggtatgg ctattactaa gtcatattgt ggaatacaac
    10921 aaatagcatt tcctccagtt cccattgctg aataccacaa aacaccatct tttttacata
    10981 gccaccacag ataaccgtat tcattactat tcattttaac tgattcttca atccacgatt
    11041 tagatataat acgtttatta ttccaaatac catcatttaa atacagaaaa ccaaatcgca
    11101 acatatctct agcactcaat gtaagtcccc agccacctat agaataaccc tgtctatctt
    11161 ttgcccaacc cttaagattt tttccaaaga aatcttcaaa accaaaatct ttcatatcat
    11221 aatctggtat aactttcata ccaataggtt taaataagta ctcattagca aattcacgag
    11281 cagattttcc agtagttttt gttataatag ctgaaagtag gtgcgttcca gctgaagaat
    11341 atttgaaagt accaatttcg cctttttgac caagttgatt caaggtatat tttatccaat
    11401 ctttttgttt gcaaagtctt tctaaagact cagtcatatt tttaaaaggg tatggtgcag
    11461 tcattgtaag taggtgacgt atagttactg cttttttaca tatttcagaa ggactacaag
    11521 tatattcagg aaaaaaatca acaacctttt ggtcaacatc ttttatatat cctttatcta
    11581 ttgcaatacc tattaaggct gatataatac tttttgtaac tgatgcaaca tgaaaagtat
    11641 catcagcatt atatccatta tagtactttt caaagacaat ttttcctttt cttgcaataa
    11701 ttataccatt tatattgcta tattgtgaga ttattaaagg ttcaagttgt gaaagctttt
    11761 ctgaactcat accaacactt gaagggtcta ctttttcaaa aattaagtct aagcaattgt
    11821 ttttattcat taaagatacc tccctgttat agattttgga ttttctttta gagcttttgg
    11881 agaaccttct gcaattatat aacctccttt gtcaccacct tctggaccaa gctcaacaat
    11941 ccagtcacaa acatttaata catctatatc atgttcaaca acaattacag aatttccatt
    12001 ttcaaccaat tcatctaata attgaatcaa cttagaagta tcatatagac ttagaccagt
    12061 agttggctca tccaatacat aaaggatatt accatttcgt tttttaccaa tttcttttgc
    12121 aagtttgatt ctttgggatt caccaccact taaatttggt gtaggttggc ctaattttat
    12181 ataccccata cctatttgtt ctaatacatt taagtgtgaa acaatatttg gaatatcctt
    12241 gaagaaatat acagattcag aaacactcat atttaaaata tcatgtatat ttttattttt
    12301 atatttaata gataaagatt catcattaaa tctttttccc tgacattcac tgcatatatg
    12361 gtctatactt agattatttc ccaaccagac cttttcatat ccactaccac tacatttagg
    12421 acaagcacct ttggagttaa atgagaaatg accagctgta aatcctcgtt ctaacgattc
    12481 tggctgacct gcaaatagtg tacgtatctt atcccatata ccaatataag aagcaggagt
    12541 tgagttcata tttttgccaa taggagattg ggatatctct gaatatccag aaatatgttt
    12601 agtaccaatc agtctatctg caatagtttc aacaactgca taatcgtctt cctcacctat
    12661 ttcactctct gaagaattta tttgattatt gatagtatgg ttattaaatt ggcttctaag
    12721 aagaggaagt agggtgtctg atataagtga actcttgcca ctacctgatt ttccagatat
    12781 tccaaccata gcactcaaag gtaatgatac agttacattt ttaagattat ttgtatttgc
    12841 attttgaata gttatacaag gtattttatc agtatgtgta atatttttat tgcttgttct
    12901 attaggcatt ggatattttc cagatagata ctgcccagta agtgatttgt tggattgaag
    12961 tagaccttct aaatctcctt gatatactaa ttgaccacct tcaacaccag cttttggacc
    13021 aatatcaata atatgttctg ccattttaat tgtgttttta tcatgctcaa ctactatgac
    13081 cgtattgcct aaatctttaa gtttctttat tgattttaag atgtctattt tttctgattc
    13141 atgcaatcca gctgttggtt catcaagcac ataaattaat gagtccatct ctgaatcgag
    13201 atgtgaattt aaaaatagtc tttgcatttc cccaccactc aaagttgaca tttctcggta
    13261 taaggataga tgacctaatc gtgattctat taaatgttga gttttggata aaatatcatt
    13321 tacaagattt gtaccaaatg tgtttaaatt accttgattt attaagagtt taaggaaatc
    13381 atcaatttct aaaatcgtca tttttccaag ttctccaata tgttttccgt ttaaaagtac
    13441 tctacgtgct tcttcaccaa ttttaaaacc attacaatct gaacaggcag tcatagtata
    13501 aactccattt aaatcttcgc cccttttgta acgattgtga aatacctttg ataaagagga
    13561 acttttttta ccattttcat aatgaccata gagtacttca tttcttattt cttcaggtag
    13621 ttgtaagaat tgtatgtcta aataatcgtt gaatttttta gaaaatactc tcaaatatcc
    13681 tggtgtaatc tttgctctat ctaagacttg ttttagggtg tcatgcttat caaggactaa
    13741 tttttcaata ttaatctcaa aatatgcacc atgtccagag cacttcatac acattccatc
    13801 tgaagagttg tatgagaaat aacttggtct taatcgttct tcctcatatc cacaattatt
    13861 gcaaattaga ttatcgctta taggagtatc acacatagta cacattattt gaccttccac
    13921 tgaatacaat agtgtaagca tgttgagaat attggttctt gtgcctactg ttgaacgagg
    13981 attgctctgg cgaataatat tttgttgaac agctatagtg ggagctaaac cttgaatatt
    14041 atcaaactta tcctcactat caatacctgc aagtatacct aaagattgca gatattgttt
    14101 acgcccttcc tcaaatacaa tgtcaaacat aaggctagac ttacctgagc cactgacacc
    14161 tgttgcaaca acaagcttat ctttggggat agaaacatct atatttttaa gattgtgtat
    14221 ctttgctcca ttaattttta tttctttcat tggttcacct cattttatca attttatcaa
    14281 accgtaaaat agggatatat taatccttaa tacaagaata gattaggtga ggttattaaa
    14341 aaggttctat aggtaaatat atatcgacca agtgtctatt ttgagggtga ttgtgtgggt
    14401 tgttaagata tacttcaaaa gggaaggagg cacgtagctt ataattacca tttgatagcc
    14461 attcattata cataaaatcc cacgcatcac tatattcaga ttttgaaata tcaaaatgtc
    14521 ccacaagata ttttccagaa ggtattatca tattgccaag attgtcattc tctttgacaa
    14581 ctatgttatc tggaatggtc atgcaaatac tagtccttaa ttgatgctcc tgtgtaaatt
    14641 gtggattatc atgataaatg gctaatattt gtgtgttttc aagtccaagt agattctgct
    14701 cacttgcata tgtgaataac cgttctaaaa gttttgggaa agtactggtt agattaccat
    14761 atgaaccagt atatctagtg taaatagtat tcatattatc aagttctaga atttcaattt
    14821 cacctttaac ctctctagta ttcttacatt taggttttga tatgcttcta ttgtactgag
    14881 aaattttata tggttctttg caattcttgc tataattgtt tctatatttt atagggctta
    14941 ttttatagta atttttaaat gctctcgaga aaactgctga atcagtaaag ccaaagtagt
    15001 gtgcaatatc agtaacagtc atgtcagttc tatgaataag aaaagcagtt gcattttcta
    15061 gttttagcct atttacatat tgtgccaaag tttctttttc tattgctttg aagattctat
    15121 gaaagtgaaa ttttgaaaaa cctgctatat tagaaagttc atcaagagaa agaggttcat
    15181 gtaaatgttc ttctatatag tcttgcactt tgcaaatacg atttagatat tcttttttac
    15241 ttttagcatt tgtcatatat agccctcctt attgtgtaaa atgtgtatca attaatttat
    15301 agcaatatag taataaaatt ttatgttttt gtaatttatg ataaataaga tagcgtttaa
    15361 ttttttataa ttgataaaag atatttataa ttaataaaag atataagatg ccttatattt
    15421 atctttgcat ataagtatag tcttcgtaat aattagtata ccatagtgat ttatttttaa
    15481 ttgtgtattt atataaatac acaacttatg atatggacga attattatgc aaataagctg
    15541 taattaaata aattgcaata taaaccagtt gaaacataag ttagggaaat attatcaaag
    15601 ttattattta gcataagact atagatggaa taaaataaga ttaaaaaatt acata
//
LOCUS       DAEPXW010000091        15585 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.092, whole genome shotgun sequence.
ACCESSION   DAEPXW010000091 DAEPXW010000000
VERSION     DAEPXW010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15585
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.092"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            41..892
                     /locus_tag="KRM55_002868"
     CDS             41..892
                     /locus_tag="KRM55_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBH1595085.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1025..2638)
                     /gene="ggt"
                     /locus_tag="KRM55_002869"
     CDS             complement(1025..2638)
                     /gene="ggt"
                     /locus_tag="KRM55_002869"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBH1595086.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2863..4800)
                     /locus_tag="KRM55_002870"
     CDS             complement(2863..4800)
                     /locus_tag="KRM55_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595087.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTVKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4787..5554)
                     /locus_tag="KRM55_002871"
     CDS             complement(4787..5554)
                     /locus_tag="KRM55_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595088.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNKLADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNKEFYNKIVNTVSLIGGVNKNDFI"
     gene            5842..6516
                     /locus_tag="KRM55_002872"
     CDS             5842..6516
                     /locus_tag="KRM55_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595089.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6540..7544
                     /locus_tag="KRM55_002873"
     CDS             6540..7544
                     /locus_tag="KRM55_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595090.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7656..8885
                     /locus_tag="KRM55_002874"
     CDS             7656..8885
                     /locus_tag="KRM55_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH1595091.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIISEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            8893..9567
                     /locus_tag="KRM55_002875"
     CDS             8893..9567
                     /locus_tag="KRM55_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595092.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9570..10802
                     /locus_tag="KRM55_002876"
     CDS             9570..10802
                     /locus_tag="KRM55_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595093.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFTATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11088..12353)
                     /locus_tag="KRM55_002877"
     CDS             complement(11088..12353)
                     /locus_tag="KRM55_002877"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBH1595094.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRNKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12406..13554)
                     /locus_tag="KRM55_002878"
     CDS             complement(12406..13554)
                     /locus_tag="KRM55_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH1595095.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKDYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13654..14199)
                     /locus_tag="KRM55_002879"
     CDS             complement(13654..14199)
                     /locus_tag="KRM55_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH1595096.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14422..15366)
                     /locus_tag="KRM55_002880"
     CDS             complement(14422..15366)
                     /locus_tag="KRM55_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH1595097.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
BASE COUNT         5446 a         2424 c         1950 g         5765 t
ORIGIN      
        1 aattaaaata aagataatat aaacacagga ggtacattct ttgaaaaaca ttatttcagc
       61 aaaagaactt atatcaaaac tagaaaaaaa tgataatcta gttgtaatag attgtagatt
      121 tgatcttatc aatagaactt atggtattga ttcttataaa aaaggacaca tcaaaggcag
      181 ttttatctta gatatagaca aggatttatc atctcctaca aaagaacatg gtggtaaaaa
      241 tcctttacaa gaccctttaa tactaaaaga aaaattagaa aaaatgggtg ttgataacga
      301 cactacgatt gtaacttatg atgatggaga tttaaatgga gcttgcagat tatttttcca
      361 attaaaacat ttggggctta aaaatgtcta tgtactagat gggggaataa catctttcgt
      421 aaaggaaggt ggagaattgg aagagaaagt gaatatacca agttgtacag gtaaggaaat
      481 tagaccaaat ataaacaatg atttagttgt tccaatggaa tatgttaagt ctaaattata
      541 caaaaaagat actgtaataa tagattgtcg tgctaatgag agataccagg gtttagttga
      601 acctgcttac tcaaaagctg gtcatatacc aagtgcaaaa aattattttt gtaaggattt
      661 aataaaaagt gactttgaaa atggctcact taaagatata gaatttttaa aaaaattctt
      721 taaagattta aataattatg atgaagtaat tttatcttgt ggttcaggga tatctgcttg
      781 tgttaacagt cttgctctta gagaactgga tatacctcac aagatttata ttggtagctt
      841 tagcgactgg attagttatg atgacaatga aatcaaaact ggtcaagaat aaggctcata
      901 atctatataa aatcagcata tgatagctta aattttgtaa aggcgtcagt cattgtagac
      961 tttcgccttt acttattatt tcatatactc tttaaattta ttatatatat tttagttgat
     1021 aatattaata aactgcaata tgaccatcac atcttgattc cgtcccacaa atataacttt
     1081 cctgttctgt tttaaatatt atttgacctc gtcccatgtc gacagtatca tgaattactt
     1141 ttatttcatg acccttttca attaatgaat ctattatatg ctttggcatc tctggttcaa
     1201 cttctatttc ttttcctttt atccactgcc atcttggagc atctagcgcc tcttgtggat
     1261 ttaatccaaa atcaatcata tttgttaaca cctgaatatg tccttgtggt tgcataaaag
     1321 ctcccattac accaaatgga cctattgctt tatcttcttt acctaaaaat ccaggtatta
     1381 tagtatgata aggtttttta aatggtttta ctacattgtg gtgtttaggg tctaaattaa
     1441 aattatttcc tctactatgt aaagcaatcc cagttcttgg tatcacaatt cctgaaccaa
     1501 aatttatgta attgctctgt atatatgaaa ccatatttcc atccttatct gcagtacaaa
     1561 ggtatactgt accaccacaa tatggctctc ctgcagttgg atacaaagcc tctttattgt
     1621 caattaataa acttcttttt ttggcatact cttggcttag taattcctga atctttacct
     1681 tcatatgctc tatatcagtt acatatgttt tagaatctgc aaaagctaat tttaaactct
     1741 ctataatttt atgtatgtct tctacatttt ctatatttcc ttctaattcc aattctttta
     1801 atatgttaag tgccattaaa actgttattc catgaccatt tggtgggatt tcaaatattt
     1861 tatatccctt atattctgta cttataggtt ctacccatgt tggataaaaa cactctaagt
     1921 cactctttct tatagcccca ttaaattttt tagaatattc atctatttta tcagcaagtc
     1981 ttcctctata aaagctttca gcctgagtat ttgctatctc ttctaatgta cttgcctgtt
     2041 cttcacatat aaatatatct ccagcctctg gggctttacc atctttagaa aatgtatcaa
     2101 accatggttt gaactcttct ccaataagtt ctttttcata gagttcatat gattttttcc
     2161 ataccttagc tacattagga gatactacgt atccctctct tgcatagttt atcgctggag
     2221 ataagcattc cattaagcta agtttaccat attttttatt taattctgac caagctgctg
     2281 gtattccagg tacagttact gctccaaacc catattttgg catttctttc atattattat
     2341 aattttttaa ttccatattt tctggagcaa agccactaga atttaaacca tacaatcgtt
     2401 tttcttcctc tatccaaaca agggcatatg catctcctcc aatcccattg cttgtaggtt
     2461 ctactactgc taatgtggcg gctgttgcaa ctgctgcatc aacagcattt ccaccctttt
     2521 ttagtatttc aagtccagct tgagatgcta gtggtgttga tgttgcaact gctccatttt
     2581 tagcatacac gacatttctt attgatgagt atttatgttg gtaggcatta aacttcataa
     2641 atttcagctc cttgtcattt tttatttgat attctgctta gatttattat ataacatcaa
     2701 gtaatgtaac tgatacaaaa tgatataaaa tatagacttt ttcctaactt taattttatc
     2761 tttaaataaa tatcttaaac tcaattctag tattttctat ctgcacttaa ataagttatt
     2821 ttattcaaaa catatatcta attcttttga cttaaaaata atttattctt ttatcatgtt
     2881 tagagcatat tttaaagtta aaaaataata tataaaatat cctataaaat aaatgactag
     2941 agttatgata attggtacaa gtaatgacct tggtataaac ttttgtgcta tagacatagc
     3001 aaataaatta tgaactgtac ctacaactaa tggcattaaa aatataactt ttaactgttt
     3061 tgatattatt ttctcaatat ctttattatt tgctccaagt tttattaaca taatatatct
     3121 ttccttatca tcatatatat ttgataattg tttaaataag attatactac ctgtacataa
     3181 aagaaatact acagacaaaa atatgcctat aaacagcatt agaccactta attttatcaa
     3241 gttattataa ctttcaatac ttgatgtaaa attaaaagga taagtaaatt tcatattttc
     3301 acttactata ttttttaatt ttacagtcaa atccagttct tttttttcat tttttatatc
     3361 aattaatctt attaatctag aatttccatg taattttaac tgattaaata cgtcatcttt
     3421 tactacaatt aaatcaaacg tagcttgtga atttatttct ggctccaaga tgcttttttg
     3481 tactttaaac agatttatat catactcatt tgtatcttta atatgcaagt ttattttttc
     3541 aatctcaaag tctttaaaaa atattttttt gtatgaatca gaaacatagt acacagattc
     3601 ctttgaagtt aattcttcat aattgttatt ctgatattgt cttaattttt taaaatcact
     3661 ttctctaata atatctacag acgttctatc ttctatataa ctatttccat ttttataata
     3721 catttcaata tttatatctt tgtctataag ttctattgtt ttatcaaaga ttatcttatt
     3781 atctttttta tatttatata ataatttgtc aatttcgtta tttacataag aatttcctaa
     3841 atttatggta taactgtatt tataattttc acttatgttc ctatctatat cgtaataaag
     3901 tgatatggta aaccctagca tagttacact tgtagctatt aatattgcta ttacagccaa
     3961 tacactacta ttgctcttta atttaaatcc aagttcagaa aatgcaatta aattctgtcc
     4021 cttataataa aaactttttc tcttcttaac agcatcaata atcatataca tagttgatga
     4081 aaaaaataaa aaagttccag gtattattgt aactaatata aaaactgaaa gcataatatt
     4141 ttcagcaata aaataactaa ttgacattaa ataagaaata gctattaata aaacaccaag
     4201 tacacatttt aactttataa attttttaaa cttatacttt tctggatatt tattaaataa
     4261 ctctataatt ctcttatttc tgataactat agtatttctt attccaataa ctataaatat
     4321 tattaaaaat actgctagtg tctgaactaa ggcctttata cttaagttca tatttactac
     4381 tatcatttca ttcattaatt ttacaagcat catagtcata agctttgaaa ataacaatcc
     4441 taaaaatata cctattaata ttgcaactat acccatcaaa aaagtttcat ataaaaatat
     4501 ttttcctatc tgatttttcc tcattccaag taaactataa gttcctactt ctcgcctacg
     4561 tctattgaaa aaaaatgagt ttgaataata tataaataaa aatacaaata ccactattac
     4621 aattgaactt gtattaatac tcatcctggt tttctctcca agtgaactca acgcttcatt
     4681 atactctata gatttaaaac taaaaaatac aaatacacta aatacaattg aaataaagta
     4741 cattaaataa ttaaaaaaac tattctttac attttgcatt gcaattctaa ataaagtcat
     4801 ttttattaac tcctccaatt aaggaaactg tatttactat tttattatag aactctttgt
     4861 tactttctcc ctttacaatt tctgtgaata ttattccatc ctttataaag agtattctat
     4921 tgcaaaaact cgcacttata gcatcatgag ttaccatcaa tattgtttta ttgctgtctt
     4981 tgtttaattt taatagacaa ttcaacaaat ccctagcaga tttagaatct aatgctcctg
     5041 taggctcatc tgcaagtact aatgatggtt ttgttgctat agctctacat acagctcctc
     5101 tttgcttttg tccaccagaa acttcgccag ggtatttatc taatatagat tctatattta
     5161 attcttttga aatctctttt attctatttt ctattactga tactctttca ttttttaaag
     5221 aaagaggcaa cattatattt tcttttattg taagtgtatc caaaagatta gaatcttgaa
     5281 atacaaagcc tagattatca cgtctaaaat ctgccaattt attttgcttc attttaatag
     5341 tattctttcc atttatataa atatctcctg atgaaggtaa atctattgta gaaataatat
     5401 ttaaaagtgt tgatttacca gcaccggaag accccataat accaacaaat tctcctttat
     5461 aaaccttgaa agttattcct cttagagctt catgttttga accttttctt ccatactcct
     5521 tttttatatt ttcaacagat aatatttctt ccatagttaa taatcacctt tcatcacaat
     5581 tagttattta tcaattctca caaatatatt atatatatta aaatggcttt taaacattta
     5641 attatattaa tttaaggtta cattttcgta agtattaatt atatttcttc aaatttattg
     5701 caattatgtt taaaatataa tttatcaagt aaaatatagt tatattaata taattatttt
     5761 aggtaataag gtagaaatat tttaatttat caagtagaat atagttatgt taatataact
     5821 attttgaatt aggaggtaag aatgtttaaa ataatggtag ttgaagatga cgtctcattg
     5881 aaaaatatca tagcaaagtg tcttactaaa tggggacatg atgttcatca aatagaaaat
     5941 cttgaaaata taatagaaga gttcaaaaac tataacccag aattagtttt attggacata
     6001 aaccttccat tttatgatgg ttttcattgg tgtaatgaaa taagaaaaat ttcaaaagtt
     6061 cctataattt ttatttcttc aagaaattct aatatggatg taataatggg tgtaaattta
     6121 ggtgcagatg attatataca aaaacctttt tctgtagatg tcttagtagc taaagttaat
     6181 gcccttttaa gaagaactta taattttgtt gataataact caaatcagat tattcacaat
     6241 ggtgttactt tagatttatc aactgcaaca ataaactatg aagataatac tattgagcta
     6301 acaaaaaatg aaatcaaaat tctccatgag cttatgaaat ataaggggca gatagtaagt
     6361 aggaataaac tcatgaaaaa attatgggat aatgattggt ttgtagatga taatacatta
     6421 actgtcaatg taaatagaat acgctcaaaa ttaaatgaaa ttggtttaga agattttata
     6481 gaaacaaaaa gaggattggg ttatataatc agttaaaaca attctaagta ggtgaattta
     6541 tgagctttaa agattttctc aaggataaac taggtttttt agtatacaat tttactttct
     6601 taatttttac agtatcagtt attatatttt ctcctgtaga tgtttttctg actgatacta
     6661 ttttatatat attagttgta aatgttgtgt ttttattttt atatctattt attagctaca
     6721 tcaagaagaa caaattttta gataagataa aaaatgatac attcaaaatt aatatgaatg
     6781 atatagaatt agctagatgt aaaaatgaag aaaaaatata cttgaacatt attaaaaatc
     6841 atcaatatca atgtaataac ataataaata ataatatcga gaaatttgaa gaaaacaaag
     6901 agattttaaa tatgtgggta catgatgtaa agatacctat agctataata aaactcattc
     6961 ttgaacaaaa tgaaaattta attgatgaaa aaatttcaga tgacatagat agtgaaatat
     7021 ttagaattga aaactccgtt gaaaaaattt tatatttatc aagactcgaa gattttcata
     7081 aggatttttt aattcaagag gtaaatattg aaaaaatcat tagaaatatt ataaaaaaat
     7141 actcaaaata ttttatttca aaaaaaatta ttttagactt aaataatttg aattttaagg
     7201 ttttatctga tgaaaaatgg ctatacttca tattcgagca attattgagt aattccctaa
     7261 aatactcctc attaggagat aatatatcta tctattgcaa aagaaccaaa aattatttac
     7321 aattaagagt ggaagatact ggttgtggta taaaaaagga agatttaaat cgaatattca
     7381 ataagggatt tacaggtaat aatggaagaa acaattctaa atctacaggt cttgggcttt
     7441 atttagtaaa agaactttgt gataagcttg gtcataaaat tgatgtagat tcagagtaca
     7501 accaatatac aaaatttact attacattca aatgtgattt atagtatctt attattgata
     7561 gtttattttc attaacttat attcaacttc ttatagtaat tctatatgta catcccagta
     7621 tataattaag tagtttttat aaaaaggagg aagacatgtc ttttctaaaa aaatttaaaa
     7681 ataaaagatt tagaaataac agttttaaaa gtaacaactt tagaaatagc agttttggaa
     7741 gtagtggctt caagtctaaa aataaaggtt ttaaaaacaa tccctttaaa aataagagat
     7801 tcaaaatata tgcaggaata gcagtaatca tacttttaat tctaggagtt cttgcttatg
     7861 ttgattcgaa aaacactgaa ttacaagcta atgaaaattt tatcgaaaca tatactattc
     7921 ctgaaaatga aaaaatattt ataaatggga tggttgttcc taagcaaact aaggacttca
     7981 atatatctgg agattatgag ttaagtgatg ttaatgttac aaatggtcaa aaagtaaatc
     8041 aaggagacct tctttttact gctaaaaatc caactataat atcagaaata gatagtttaa
     8101 aatcacaact tagtcaatac aaaaaacaaa aaatatcact ttctgatatt gctgaaaata
     8161 aagatgctat tgcttctata aatgcacaga taactgcttt aaactctcag atagcttctc
     8221 tggataaaaa agcttatgac agagttactg ctccttttga tggcacagta tacttgaatg
     8281 accaaactgg aaatccagac caaccagttt catttatgac tattcaaggt ctagagtttt
     8341 atatgaaagg acaagcaagt gaacaagatt tacctaaaat gaagattgac caaatggtca
     8401 atatactagt tttttcaact gaccaaaagc ttactggtag aataagtttt atatctgata
     8461 aaccatctac tccaaatact gaaatgggag ctcagcagaa tacactatct tattatgata
     8521 taaacatagc atttgataat caagaaggat tagtaaatgg attccatctt caagcatcac
     8581 ttgaagtagc taattcaagc tttaaaatac cagcatcttg tgtacttaaa gacaacaaac
     8641 actcatatgt atttaaggat ttagatggta tattgaaaaa gcaaattgta gatgtagcaa
     8701 gtcaaaatga tgattttgct gtagttagag gcggtcttga acaaggcgat ataataataa
     8761 aacaccctac taaagaaatg aaagaaggag acccagttca aggcgatggc gtaactgctg
     8821 gttctaataa tggagatact actccaaaca aaaaagtaga agaagttact atggatgtga
     8881 attaatttac atatgttaat taaattagaa aatattcaaa aatattacaa agtagggaaa
     8941 gatgaattac atgttttaaa atccttaaat ttagaaattg aatctggaga atttgtcatg
     9001 ataatgggta agtctggtag tggtaaaact actttactta atatcttagg ttttctagat
     9061 gtatttgatg aaggaagata tatatttgat ggaacagatg taactaattt gagtgaaaat
     9121 gaacgttctg tttttagaaa tattaatatt ggatttgttt tccaacaatt taatttaata
     9181 gaaactctaa atgtatatca aaatgtagag ttgcctctaa tttacaataa agcactaaaa
     9241 aaatctaata gagaagaaat tgttaaagat aaattaagtt ctgttgggct tttggacaag
     9301 cttaagcaga aaccacttca attatctggt ggtcaacaac agcgtgtagc cattgcacgt
     9361 tgcctagcaa atgaccctca gataatcttt gctgacgaac cgactggggc attagatagt
     9421 gaaactagca gagaaattat ggagctttta acaaggctca acaaacaagg taagactata
     9481 ataatggtta cacatgatca agatttaact aagtatgcaa ctaaggttat acgacttaaa
     9541 gatggtgtgt ttacttcgga ggtgtaatca tgagtttatt aaaaaattct ttggccaatt
     9601 taaaaggtca caagcttcgt gtatttgtag ctttactctg gattataata ggaataactt
     9661 cagtaatact tgttagttct ataggtaatg gatttcaaaa agaaattaag aagtctgtaa
     9721 acaatgtaaa ccctaataaa actactattt cgtttgaatc agccgataac acaggtctta
     9781 ctgatgatat gagtattttt ttaaaaccct ttaatgcaaa agatttagaa gaattatcat
     9841 ttgttgaagg agtagaaaga atagctcctt caagagatgg gtttaacctt gattcagttt
     9901 actcttcaca agcatctttt gataaaaaaa ctacgtatgt tgatgttgga ccagtaaaaa
     9961 aagattctaa aataaattta atttgtggta gagatttttc tttagatgat gaaaaaagaa
    10021 aagtaatttt acttacatta caaagtacaa gtgaaatttt tgaaaatcca gaagatgcct
    10081 taggtcatgg tatcaacata aatggaacta tatttgaaat aataggggta ttagatgatt
    10141 ctcagcaaaa ccaagctgga ggattctttg gaggttacca agatatgcaa tttactactt
    10201 ccctagtacc taaaaaggct tttgacactt taatgagtca aaattcttat tcaaatgaaa
    10261 tttaccagtt agacttagtt tcttctaaag gctataatgt aaatgaagtt gcaaacaatg
    10321 ttatagctaa attatatgag atgcaccctg gtatcaatgg ttcttatact acaccagacc
    10381 caactgaaca gacagcttat cttgaaagca ttaattccaa tgtaaacaaa tatgtatcta
    10441 taataactgt agttgcaatg tttgttggtg gtattggtgt aatgaatata atgtatgtat
    10501 ctgttatgga aagacaaaga gaaattggta taagacgtgc tattggagca aaacctaggt
    10561 ctatattatt tcaattttta gttgaagctg tttttataac agtatgtggt ggaattttag
    10621 gaactatagt tggatttact gctactaact atgtttctaa atatataggt tttgaagcta
    10681 tacctagctt aaatagctta ttttatgcaa ttgtagctac tatattgact ggagttgtat
    10741 ttggtctgat tccagccttt aaagcctcta aactagaccc tataaaggca atttataagt
    10801 agaaattgta taaagatttt cgatttttag attagtttat ataaaacata cttaaatata
    10861 taacgcacta ttatatatga tagattagga acttaatctt tccaaatata atagtgcgtt
    10921 ctttcataaa aaggattctc ttccttacta tatctaaatt accaagatgt catgttctaa
    10981 ttgttcaaac taatacttcc aattttgatt aatcaatctc attctgctaa tatacaatct
    11041 tttactttca atcattgtac actccgcctt aaaaaaataa tcttaaatta ggcgttatat
    11101 acaatctccc cattacatat tgtataatta acctttccat ataaagattt acctttaaat
    11161 ggtgaattat cagctttaga aacaaagctt tcaactgtcc attcttcttc tggattgaat
    11221 ataacaatgt ctgctacagc cccttcttct ataaatccaa tatttaaatt gtacaacttt
    11281 gcaggattta tagacatttt ttctattaac tgcatcatac taagatgatt tttatgcacc
    11341 aaatttgtta ttccaagagc taaagaagtt tcaagcccaa taattccact tggagctttt
    11401 ataaactctc tatctttttc ttctttacta tgaggtgcat ggtccgttgc tattatttca
    11461 atagtaccat catttaatcc ctctataatc ttatctctgt cccatttatt tcttagaggt
    11521 ggattcattt ttgcatttgt tccaaactcc aatacatctt cctcagtcaa tgtaaagtga
    11581 tgtggtgaag cttctgcaac tacatttgca cctaagtatt ttgcaaatct aaccatatca
    11641 acagatacac ctgaacttat atgttgtata tcaactttag caccagtctt tagtgccaac
    11701 atacaatctc tggctaccat aacatcttct gctacacttg atgcaccttt taatcctagt
    11761 tctgaagcta cctttcctgc atttacacct ggatttccaa ctaaagaagg gtcttcttca
    11821 tgaaaactaa gtggtacatc caactctttt gccttaatca ttgcctccat aattagattg
    11881 ctatccatta aaggtaatcc atcatcagta aaccctggta caccagcttt tttaagagct
    11941 tccatatcaa ctaactcttt accttcaaaa cctttagtta tagctgctgc ttgtaaaaca
    12001 tttatacatg cattttttga cttttcttta acataattaa aagtatcttc attatctaca
    12061 ataggattag tatttgccat acatataaca gttgtaaatc cacctctagc agcagattta
    12121 gctccacttt ctatatcttc tttatatgta aacccagggt ctctaaagtg tacatgtaca
    12181 tccactaaac ctggagcaac tacattacca ctagcatcta ttattttttc atattcatca
    12241 ctttcatcaa acttgcctat tttataaatt ttattttctt ttataattaa gtcaatattc
    12301 tcatctcttt gacttttagg gtctattact ctaccatttt taattaaaat catattattt
    12361 ctcctttata tttttaattt atatagactc atataatatt atacattatt ttacatactt
    12421 aaatacaaaa ttacgtttga catcaatagc ctttttagga caaagttcat ggcaacagta
    12481 acatcttata catttactta agtctataat agcaccctta gtccctatct ctatagtgga
    12541 tgcaggacaa gcttccttgc attttccaca ttttatgcaa tcttgaaatc ttaccacagg
    12601 ctttggtgtt ataagctttg aaataggttc atttaaaaat tttggtagtt ttacggaaaa
    12661 caatcttaaa tccttactta catttggaat cttgtaatct tttataatta aatcttttat
    12721 atcttcacct aaaatttcaa tatctgaaaa atcttcttgt atatatcctc tcttaatagc
    12781 acctctaatt gtagcaactc tatttggaag taaacttata atcttacatg caacaacatc
    12841 tatagcatat ggattttgtg atgctaataa aactcctatt tctcgagtag taccagctga
    12901 aggtccatca ccttccatac ctactatacc atccataatt gtcaatgttg gttttatata
    12961 atcacaaata tctaaaagta cattttcgca aaataactct tctgtaggaa atctataatg
    13021 tatctctgct tttttcaatc cagctatgca tccatataag ttttttgtac caccagtaaa
    13081 agttgccatt atatgagtct ttaatttaca aagatttatt atataatctg aatctactat
    13141 tggtttaata atatccatat attttagaac atgtgctttt tcactatgta tcttaacatc
    13201 tgaaacatca taatttaact taatgcccag ttcatttgct acttcttcaa ttccagatgc
    13261 cttataaatg ctcttaagag aactttgatt atatggacca ccagggctat ctgctattgt
    13321 aatatcacaa tttaactcta aaagtttttc acatacaact tttacaacca taggatgtgt
    13381 agttgtagct tcttcaggct tttttttcat taataaattt ggttttataa gtactttgct
    13441 tcctttttta acaaacttat ctataccacc aatatcctct aaattttttt caatagataa
    13501 ctttacttct tcataattgt aagttttaca actcctaaca gataccgact tcatattatc
    13561 tccatccttc tatcacaaca gtttatttgt ataatttaaa aaaggagaaa ccaaagtttc
    13621 tccttttaat ctatgtttta attgttttaa ttattatttt ccaaaatgtc tgtttaataa
    13681 tcctaagaat gctttaccat gtctagcttc gtctttacac atttcatgta ctgtatcatg
    13741 tatagcatct aatcctaatt ctttagctct cttagctaat tttaattttc catcagttgc
    13801 accatactca gcatcaactc taactcttaa gttttctttt gtatctgcaa ctacaacttc
    13861 tccaagaagt tctgcaaatt tagcagcatg ttcagcctct tcaaaagcta ttctcttata
    13921 cgcttcagct acttctggat aaccttctct atcagcttgt ctactcattg ctaaatacat
    13981 tcctacttct gtacactcac cagtaaagtt agctcttaat ccttcgatta tttctgcatc
    14041 tacaccttga gctactccta ttctatgttc atcagcccaa accatttcgc ctttcatttc
    14101 ttcaaattta tcagctccaa ctttacatac tggacattgt gctggtgcag catctccttc
    14161 atgtatatat ccacatactg tacaaacaaa ttttttcata attaatttcc tcccaatttt
    14221 atataattaa atttttattt ttaagtttaa taacttgcta caagaatata tataccccag
    14281 actttatagc ttaaacacta aaaataaaat ttatttccta attaatttta tcactttgaa
    14341 acaccagtat caaccaagtt ttgatgtcaa atttctacat aatacataat ttatttgatt
    14401 aattaggaaa tagttgtcat attaaatact ttctaatgaa gactcctctg aatctttaag
    14461 tttcactttt ttgctcttta aaaaagataa tttagtttct gcagttatga ttgcaacaaa
    14521 tatcaagata ctaccaataa ccaattttgc tgtaataagc tcctttaaaa ttattataga
    14581 aaatattgta ccaaatacag cctctgtgga taatattata gctgttctag ttccatcaac
    14641 tcttttttga catatagtct gaaataaaaa tccaattgta gtactaaata cagctagata
    14701 catagttccc atgtaaccag ataattcagc ttccatcttt aattgacctg caaatgtttg
    14761 aactacaaca gacattaaaa acgctactgt aaattgaata gctgtcaatg ccattgggtt
    14821 gttatctttt gcaaactcac ttgtaaagaa tatatgaaat gcaaatccga atgaacatat
    14881 aagtgttaga aaatctccaa aattaataga gaaatcagct tctaaagaaa gtatcccaat
    14941 tcctataaga gctaccaaac tacttattat tcctatttta tcaagttttc ttctataaag
    15001 tataaatcct atgaacggaa ctattacaac attagctgct gttataaaag catttttaga
    15061 tggtgtagtg tacataagtc caatagtttg tactgtgaat gctagaaata aaaatattcc
    15121 taaaatccct cctgctttta ataatttttt acccatattg gcacgaatct gtttaaaaaa
    15181 cagtaaattc ataattatag ctgccaagaa aaatcttaaa gttatgattt gtagaggtgt
    15241 aagcccaccg tctaatgcaa attgggttgc tacaaagcca cttccccata taattgctat
    15301 aaatattagt cctatttctc caaagtattt tttcaataaa gccccctcct ttttattttt
    15361 ttgcaaaatt ataaaccccc taaacagcaa gagagttttt ctataagcat tactataaat
    15421 taatatagta aattttttca gtattttaaa tctaaattta catacatttt gagctcaaat
    15481 ttatatccac tatttaacag taatatatta atcatttttt gtaaacacct ttttaataaa
    15541 tttttatatt ttttatattt ttttacctat actaaatttt ttata
//
LOCUS       DAEPXW010000092        15524 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.093, whole genome shotgun sequence.
ACCESSION   DAEPXW010000092 DAEPXW010000000
VERSION     DAEPXW010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15524
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.093"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            51..869
                     /gene="larE"
                     /locus_tag="KRM55_002881"
     CDS             51..869
                     /gene="larE"
                     /locus_tag="KRM55_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBH1595098.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            924..2072
                     /locus_tag="KRM55_002882"
     CDS             924..2072
                     /locus_tag="KRM55_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBH1595099.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            2208..3596
                     /locus_tag="KRM55_002883"
     CDS             2208..3596
                     /locus_tag="KRM55_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1595100.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            3625..4323
                     /locus_tag="KRM55_002884"
     CDS             3625..4323
                     /locus_tag="KRM55_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595101.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            4326..5759
                     /locus_tag="KRM55_002885"
     CDS             4326..5759
                     /locus_tag="KRM55_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595102.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            5781..6518
                     /gene="truA"
                     /locus_tag="KRM55_002886"
     CDS             5781..6518
                     /gene="truA"
                     /locus_tag="KRM55_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH1595103.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    6629..6836
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7089..8288
                     /locus_tag="KRM55_002887"
     CDS             7089..8288
                     /locus_tag="KRM55_002887"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBH1595104.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            8535..9581
                     /locus_tag="KRM55_002888"
     CDS             8535..9581
                     /locus_tag="KRM55_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HBH1595105.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSKMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            9689..10852
                     /locus_tag="KRM55_002889"
     CDS             9689..10852
                     /locus_tag="KRM55_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1595106.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(10942..11322)
                     /locus_tag="KRM55_002890"
     CDS             complement(10942..11322)
                     /locus_tag="KRM55_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBH1595107.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(11325..11984)
                     /locus_tag="KRM55_002891"
     CDS             complement(11325..11984)
                     /locus_tag="KRM55_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBH1595108.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(12090..13064)
                     /locus_tag="KRM55_002892"
     CDS             complement(12090..13064)
                     /locus_tag="KRM55_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH1595109.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(13104..13451)
                     /locus_tag="KRM55_002893"
     CDS             complement(13104..13451)
                     /locus_tag="KRM55_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595110.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(13669..14625)
                     /locus_tag="KRM55_002894"
     CDS             complement(13669..14625)
                     /locus_tag="KRM55_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBH1595111.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            15068..15436
                     /locus_tag="KRM55_002895"
     CDS             15068..15436
                     /locus_tag="KRM55_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBH1595112.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         6110 a         1655 c         2527 g         5232 t
ORIGIN      
        1 aagaatgtaa aaaaataata tatagtttta tagttcatat ttttccagat atggaggtaa
       61 attttgtgaa ggaaaaagaa aaattagata aattaaaaaa aatgttactt gaattaggca
      121 gtgttgtagt tgcttattct ggtggagtag atagtaattt tttgcttaag gtcgcaaaag
      181 atacattagg tgaaaatgtt atagctgtga ctattcatgc aatgatgcat tcaagtaggg
      241 aaattgaaga ggctaaacaa tatactcaaa attttggtgt taaacatatc atattaaata
      301 tagaaaactt tgatttaaaa gaatttaaag aaaatggtgt tgatagatgt tatcattgta
      361 aaaaatatat attctctaaa ataaaagagg tagcaaaaga acataatata aagtacatag
      421 tagatggaac aaatatagat gatttaggag actatagacc tgggcttaag gcattaagtg
      481 aattaggagt aattagtcca ttaaaagata gtagtttaaa aaaagaagaa attaggtcgc
      541 tttcaaaaac attaggatta aatactttta ataaaccatc atttgcatgt cttgcgagta
      601 ggatacctta tggagttgaa ataacagatg aaaatttaag aatagtagaa aagagtgaag
      661 aatatctatc caatttaggt ttttctcaat ttagagtgag aatgcatgga gatatagcta
      721 gaatagaagt tggacaggaa gaactaggta aattttttga aaataacaat tttaataaag
      781 ttgatactaa attaaaaata tttggcttta aatatgttac actagatatg tcaggatata
      841 aaatgggaag tatgaattta aatgtgtaga ttattttaaa aataaataag ttttatagtt
      901 aatataagga aacaggaggt tttatgaaaa attatacgtt aatatcgcca tgtttttttg
      961 gaatggaaaa aatgctggct agagagatta ctaatttagg atatgaaata ataaaaacag
     1021 aagatggaag aataacatat aaaactgatg agtttggaat agcaaagtca aacatgtggt
     1081 tgagatgtgc tgaaagagta catcttaaaa ttgctgaatt tgaggcaaaa agctttgatg
     1141 aattatttga aaatacaaaa agaataaact ggtctagata tataccttat ggagctcaat
     1201 ttcctatatc aaaagcttcc tctataaaat caaaattata cagtacacca gatgtacaag
     1261 ccatagtaaa aaaggctata gtagaaagct taaagaaaag ttatttggag gatggtttgc
     1321 ttaaagaaga taaggagaaa taccctattt ttgtatttat acacaaagat aaagtaacca
     1381 tttctataga tacaacagga gatgctttgc ataagagagg atatagagaa aaggcaaata
     1441 aagctccaat aagagagact ttagctgctg ggcttattta tttaactccc tggaaagcag
     1501 gtagagtttt agtagaccct atgtgtggtt ctggtactat attgattgaa gctgctatga
     1561 ttggtataaa tatggcacct ggcttaaata gagagtttat atcagaaaag tggagaactc
     1621 ttgataagaa aatatggtgg gatgtaagaa aagatgcttt taataagata gataatgaat
     1681 ctaaatttaa gatttatgga tatgatatag atgaagaatc tatagatata gctagagaaa
     1741 atgctgaaat agcaggtgta gatgaatata tagagtttaa tgtaggagat gcaactcaat
     1801 ttaaaagtga agatgagttt ggatttataa tcactaatcc tccttacgga gaaagattag
     1861 aagataaaga cagtgttaaa cagttgtata aggagcttgg ttatgcattt agaaaattaa
     1921 aaaattggtc gtattatttg ataacttctt atgaagactt tgaatatgag tttgggcaaa
     1981 aagcagataa aaaaagaaaa ttgtataatg gtatgttaaa aactaacttt ttccaatatc
     2041 cgggtcctaa gcctcctaga aataataaat aagttttaca tgatttattt gtaaaatata
     2101 aaattttatt aaaataagta aaacattatg atgccttgaa acgtctaatt attgtgagga
     2161 gatttttgtg aacaaattta aagatttata ggattaggag gagttaaatg aaagtgttaa
     2221 agcttattac tgtagtagcc ctgatgatgt tatttgttac tggatgtaat ataaaaactg
     2281 aatctccaga acaattagcg aagatacctg actatgatga tacaaaaaaa gtattgtatg
     2341 atggtattga ccagttacta aaaccagatt catctatgat attgccttct aatacaaaag
     2401 aagtaggaaa aataaataag gtagatttaa acagcgatgg aattgatgaa ttagtagtat
     2461 ttgaacaaaa agaagattta agtaataatg tgagtcaggt agggtttgta accttgagtt
     2521 acaatggaga aaaatacgta cttggagacc attttttaga aaatggcgaa tcaatagaat
     2581 atgctaattt ttatgatttg gactcagatg gatataagga agttatctta ttggttaaat
     2641 ccaaagacaa aacgaatatg catatatata aagtagtaga taatgaaata acaaaaatat
     2701 atgacttgga tgcatcatgg cttcaaaata aagaagattt taatgacatg aaagtaaaaa
     2761 ttggatatat agatggagat gacaagttag acatattgat gcttcatttg aataataaga
     2821 ctaatgaaat gtttgcaagt gttgcaaatt ttgatgggaa aatgaaaatc aaagattctg
     2881 ttaagtttga aaatgtaaaa aacttaagtg aattatatat aacattaggt aatgttgctt
     2941 catctgttgg aaattcttct gcagctataa aaggtattgt acttgatatt cctatattga
     3001 aagataataa ctatattacg cagatacttt atatgaaaga tgggaaaatt aacaaagctt
     3061 ttagtgatta tgataaaact attactaaat cttattatat acctgtagat gatattgaca
     3121 aagataagat tatagaaata cctatagttg caggcagtac aggtaataat aaaaatactt
     3181 atagttctaa atcatctgca actataagtt ggtatagatg gaatggaaaa gaaggtgctg
     3241 actcaagttt aatatttaca agtcagatat attataatta taaatataat tttaaattat
     3301 ttattccaaa taatttattt gataaaatac ttgttgaaca ggaatttgtt ggagaaaaag
     3361 cagtatttaa attttactat tttgactatt cagaccgtaa gaatttattt aatatagtag
     3421 tagagagtaa aaataaactt gaagatagaa aaaatacagg tactcaaaat tctattgtac
     3481 ttcaagagag cgatgaatat actttcttac tagttgtaaa caatgcaaat gaaatggata
     3541 agctagatat gactatagac gcattaaaag aatatttttc attaatatat ggttaatatt
     3601 atactcaatt ggaggtttta ttttatgaag gaaaagatac ttatactaga agatgaaatt
     3661 ggtattagaa gttttgttag tataaactta aaaagggaag gctatgaaat agttgaggca
     3721 ggtactggaa gagaagctat agaaaaaatg acaacagaaa aggatattac aatagctctt
     3781 ttagatgtaa tgcttccaga tataagtggt atagaagtat gtaaatttat aagggagaat
     3841 tttgaccaag taggtataat aatgcttact gctaaagctc aagaagatga taaaatagaa
     3901 ggatttatct caggagcaga tgattacatc ataaaaccat ttagtataaa agagctttta
     3961 gtcagagttt ctgctcttct tagaagagta gcaaaggatg attcaagtgt taagtcgagt
     4021 gagatagttt ctccaccatt tatacttgat atagacaaaa gaaaattatt taaaaatgga
     4081 aaggaaattg agcttacacc aactgaattt tcaatagtga aatatctaat atcaaatgct
     4141 aagcagtcgt taagtagaga ccagatatta gacgaagtat ggggaactaa ctatttatat
     4201 gattttaaaa tagtagatgt aaatataaga aggataagaa ataaaataga agatgaccca
     4261 tcaaaaccaa aatatataca aactatttgg ggttatggat actgttttag aaaggaagaa
     4321 taatagtgtt acattttgaa ggtctgagaa aaaaagtaat aaaaaactat tttataataa
     4381 ttattataat ggttactctg tttgaaggat tgttcatgtt ttacatacaa aactactatt
     4441 atgattctgt caaacagcta cttgaatctg aaataaaata tgctgatgaa tataatgcta
     4501 ttacaatgga aactacaagt tttgagaaaa aagtaaaaaa tatatttgat aaacaaccct
     4561 taactaaaaa ttcagaattt ggaatttcaa taatagataa agataaaaat attatattag
     4621 accaatatgg ttttaaaagt aaagaaaaag caaactatga agatgttaac aatgcattaa
     4681 aagatataaa aactaaaaat ttaacacctt atacttatag aataccagat acaggggagc
     4741 atgttatgag tatctcctta ccacttaagg taaataatat aatagaaggt gttgttagat
     4801 atacagtatc attagatgct attgataatg caatattaaa gcaagctaca tggcttatat
     4861 tagcaggaat atttatactt attatagcta tactaataag tcttaaattt gctgagactc
     4921 ttataaaacc attacgagag ctaaagaaat ttgcaaatga attggctgta ggaaattata
     4981 atataaaatt agaaaagatg aagattgtag atgatgaaat tggtgattta gcacagacat
     5041 ttgaacacat ggcacatgag attgacaaaa gtgaaaaatt aaaagaggaa tttatatcat
     5101 ctgtatctca tgaactaagg actcctctta catctataaa ggggtggagt gaaaccttag
     5161 gttatgaaag tataacaaga gaagaactag acttaggttt aggcattata caagatgaaa
     5221 cagaaagact tataaaacta gttgaagaat tattagactt ttcaaggctt tcttcagaca
     5281 ggataaaact tcatgttgat atagttgatg ttgaaggttt aattgtaggt gttgtaaatc
     5341 aacttaaagt taaagcagct gaaaaagata tatcactttt atttgaattt gaaaatgaat
     5401 ttatagagaa cattcaagga gataaaaata gattaagaca ggttctcata aatttaatac
     5461 aaaattcatt taaatttacg agtcaaggtg gttacataaa agttgtagct tctcaagatg
     5521 aagagataac aaccatatca gtagaggata atggttcagg tatagaaaag caaaatttaa
     5581 ataaagtgtt agataaattt ttccaagaag attataataa ggctggtagt ggattaggac
     5641 tagcaattag taatgaaatt gtaaaacttc atggtggaag aatgaaaata gaaagtgaaa
     5701 agaatgttgg aacaaaaata acttttaata taaaaaataa atttgctaaa caagcataaa
     5761 ttcttagaaa gaggattaag atgagaaaca taaaaatgat agtagcatac gatggttcaa
     5821 gatataaagg atatcaaaaa ttaggtgaca ataatatgac tattcaagaa aaacttgaaa
     5881 atgttttaag taaaatgact aatgaaacag tggagataat aggttctgga agaactgata
     5941 tgggagctca tgcaagagga caagtggtaa attttagaac taattgtatg gattctttgg
     6001 ataaaattca aaaatattta tatgaatatt taccagaaga tatagttgta aaaactgttg
     6061 aagaagttga tgaaagattt cattcaagat acaatgtaaa atcaaagact tatatgtata
     6121 aaattgacaa taataagtat cataatcctt ttataagaaa atatgctact catgtaagta
     6181 aaaaattaga tttagataga atgagaaaag caagtgagta tttagtagga gaacatgatt
     6241 ttactagttt tgcttcttct aaatctaaga aaaaatcaaa tgtaagagaa atttattcta
     6301 taaatataaa agaagatgat aatgttatag aaatatatgt agaaggaaat ggatttttgt
     6361 ataacatggt aaggataata gtaggtgctt tgatagatgt tggtctaaaa agaagagctc
     6421 cacaagatat taagtatatg cttgaatcaa aagatagatg tcaatcatca gatactgcac
     6481 cagctaaagg actatgtctt tggaaagtaa catattaatc aattatataa aactctcttt
     6541 aaaataaaaa taaaataaat tatatagttg acataaatgg aaaaataaac tattatatat
     6601 tttataagag agatataaaa ctttatattt aaatcctgtg agaaagagag taacttctat
     6661 gtgttttata gagagctgag gatggtggaa gcttggcaaa taagtattag tgaaaagaac
     6721 tttggaggat actaattgaa tttagtatgt tagtaggtaa tctcgcctta agagaaagag
     6781 tggataagtt tatcttatca attagagtgg taacgcggat atatttcgtc tcttggtttt
     6841 tccaagaggc gttttttaat atatttaatt attagtgttt atctggtatg ttgaacattt
     6901 actaattgat tagctaagtt tatcaataag agtggtaccg cggatatttc gcctcttagt
     6961 attttaaaat actaaggggt ttttttagta ttaaaatgat tttatgtgag tctaaattct
     7021 cagagtcatt caatattaag aatttctata aaataaaaat tataatttaa gattgggagg
     7081 aattaaaaat gaaggaaaaa gtagtattag catattcagg aggacttgac acatcaatca
     7141 taataccttg gttaaaggaa aattatgaag atatagatgt tatagctgtt tgtggaaatg
     7201 taggtcagga agataaaatg gaagatgtat atgaaaaagc tttacaaagt ggagcatcaa
     7261 aggcatatgt ggatgatata agtgaagaat ttgtaactga aactatattt aaagccgtaa
     7321 aagcagaggc taaatatgaa ggaaaatact tattaggaac ttctttagca agacctataa
     7381 tagctaaaaa attagttgaa gttgctcata aagaaggtgc aaaatatata tgccatggat
     7441 gtacaggaaa aggtaatgac caagttagat ttgaagctac aattgcagct cttgacccaa
     7501 ctataaaagt tattgcacct tggagaattt gggatataaa atcaagagaa gatgctatag
     7561 actatgctga aaaacataat ataaaggtaa cagcaactaa agctaaaata tattcagtag
     7621 atgctaacct ttggcatgtt tcaacagaag gtggagatat agagcaccta gaaaatgaac
     7681 ataaaaaaga tgtttataaa caatgtgtag acccagaaga tgcatgtgat gtagctgaat
     7741 atgtagaagt ttactttgaa aaaggtgtac ctaaaaaggt aaatggcgaa gaattatctc
     7801 cagttgcact gattcataag ttaaatgagt tgggttgtaa acatggaatt ggtgttatag
     7861 atatagttga gaatagactt gttggtatga aatcaagagg tatatatgag actccaggag
     7921 gaacaatcct ttatgaagca cataatattt tagaaagtgc tactttagac aaagatacat
     7981 tacatttcaa acaaatggta tcttataaat acggagaact tatttacaat ggactatggt
     8041 attgtaaatt aagagaatct atagatgcat ttatggaaca aactcaagat aatgttacag
     8101 gaacagtaaa agttaaactt tacaaaggaa atataaaacc tgctggaata tttactgaaa
     8161 atgctcttta tgatgaagga atatcttctt ttggaaatag tgaactttat gaccacaaag
     8221 atgcagaagg atttattaat ttattcactt taccattaaa aatcagagct atgaaagctg
     8281 gaaaataata aaataaatta tttaagagtg tataaaaact atttttaggt ttttatatgc
     8341 tcttttttta tttgaattta ttaaattata cagtaaatag tataaaaaaa tatattatag
     8401 ttccaaatgg cttaataatg tgaaaatata agacctaaaa tataaatttt ataaatacaa
     8461 tagttattga ctctctcatt gtaagagggt ttatactgaa tctaatgaaa atttatagtg
     8521 aggagataga ttatatgaga aaaataattg aaattaaaca tcattcacat gattatgagt
     8581 gtatgtggaa tggtatagaa gatttatata taaataaaac cggtgaatgc cttccaaacg
     8641 attttttctt tttactgtca ggttttggtt cattttgtta tatgaaaaca aataaagctg
     8701 atttgaaaag aatggtagct ttgggagatg gaaggacaaa acagatgtat aaatttttag
     8761 caccaattgt tggatttgaa tacaaacatc atgagtttaa aaagtatgag caagcattaa
     8821 agaaagcaaa atctgaaatt gatgatggat atccagttat tttaggagct ttagatatgt
     8881 attatctacc atattataag aagctatatc ataaagaaca tattcctttt cattatatat
     8941 taatggtagg atatgatgat gaaggaatat atctgtatga ttgtggtaga acagaattat
     9001 tacatctttc ttatgataaa ttacgtgaaa gcatgaattg caattcccct ggattaagca
     9061 aagaaaatac tatttgcaca ataagaatga atacttcaaa gaataaatat aacattgcta
     9121 gagaagctat tgctataaag cgtgatatgt ttttaaatcc acctaaagga tttttgggat
     9181 ataaaggttt tgaaaagttt attaaagagt taccacagtg gaacactgaa ttggataaag
     9241 atgattatga taagattttg accaatatgg ttatgttttt tggaacagta ccaacaattc
     9301 caaatgcaat caaaggaatt aaagaaccag atactgttca atttaaaggt ggatttgata
     9361 aaatgagtaa aatgctcaac agtattgggg aggaatacaa aaacgactct tttatacaag
     9421 tagctgatat ttttgataaa actgctatta taattgagaa aatatccaat attataatag
     9481 attacttaac tcaaacatgt gatgatacag aacaacttcc gttattgttc tctgaggtct
     9541 tagagcatat gaaaacagga tatttaatct tggatgtata aaaaatatat tgttgaccct
     9601 aacattacgt aatagtgtaa tatgaaaata tagcttgaat atattagtag gtattgatgg
     9661 ctgtaaaatt aaaatttgag gtgtggatat gagaacagtg aaacaagttt ctgatttaac
     9721 tggaataagt gtgagggcat tacattatta tgatgaaata ggtcttttaa aaccaaataa
     9781 aattacagat gcaggatata gactttatga tgatgaatct attaaaactc ttcaacaaat
     9841 tttatttttt aaggagattg atattccttt aagagaggtt aaggaaataa tgtcaagcca
     9901 atattttgat aaggttgaag ctctaaaaaa tcaaaaaaaa ttacttattt taaaacgaaa
     9961 gagactggat gaattgatag agcttataaa tcaaactcta agaggagaag gaaatattga
    10021 ttttaaagag tttgatatga gcgagtattt tgatgtttta gaagaattta aaagagagca
    10081 taggaataag gtaattaaaa tttatggtag tgtagaaaaa tacaatgaat atatagaaag
    10141 agttaagtct aatgaagaga aaattgctaa aatggctata aaacaatatg gaactattga
    10201 gaagtttgct aaagctataa aaacaaattt tagcagtgat atattgaatt taggagaaaa
    10261 atttgataga tataaaaatg attgtttaaa agaaaaacat ccaaaattaa aagaattata
    10321 tagaaagctt gtagaagatt taagtaggaa tccttcttca acagaccttc aagaaatagc
    10381 aaaagagata acagatatat ctaaaaaaga ttatgaaatt ttctctatgg atactggtga
    10441 tgacaactgg tattatatgg ttcaaaatta tctagtaaat cctatgtgga tagaagaagt
    10501 agataaaaag tatggaagtg gagcaggaaa gtttattgga caagtactaa agacttatct
    10561 aagagataga aaaccaaaga taaatacatt gtatgaaaaa cttgtagaag atttgagtag
    10621 agattgttct tcaagggaag ttcaaagcat tgttgaagaa atagacaatg aaatgaaaag
    10681 aagtaatgaa ttttataaaa tagacaatgg tgaaagatac tttgattata tgtcagagct
    10741 ttatttacaa gattctaact atataaaagt aactgataag aattatggtg atggtgcatc
    10801 taagtttatt ggagaagctt ttaagattta ttttgataat aataattgtt gaaaatttgg
    10861 aagtaaaaaa tatgtaagtt ttataaaagc acaaaaataa ggatgtagat tagctccatc
    10921 tatatcctta tttaaaagtt attaaaatat atagtttaca tcaaacttaa cactttcaat
    10981 aatatttccc aaatatgttt ttatactttc aacttcttct aaagatttta atttattttc
    11041 agtataaatt gctttgtcca gaatattaaa ccttaatcct atttcatcaa agtactcatg
    11101 atttaaaact ttgtaccaat ggtttttttc tttattccaa ctcgtagata ttgaatcagc
    11161 ttctttttga gctttttccc aatcttcatt ttctatagat ttttctaaaa cagatatatt
    11221 gtctttatat ccttctgtaa aatcatatag tttattgtta acataaaatc caaataatac
    11281 aaataagata gtccatagta taacaaatgt tgtagatttc aatattaatc acccttttta
    11341 ttttgaataa atattttatc attttcatct aaaacacaaa taagaacatc tttaaaagtt
    11401 tctatgtgat tagattttaa aatacccatt aaccagttag tatctttttg agctatgtct
    11461 agatttttat ttattattct accatccagt ataagtggga taggtaaatg attaaaagct
    11521 cttggaggag tactattgta gcttgatgct ggtacaacac ttagattacc atcagtctcc
    11581 aaaatagcat attgtacatc ttttaggtta aagtatcctt gaatcctaag ttgttctaat
    11641 aattcatcta tactaattct ttctttttta agctctttat atacaatttt tcctttatct
    11701 attaatacag aaggtttacc tgataaaaat gaacttaatt ttctgctttt taatgataag
    11761 aatgaaatta gagtctgcat gattacaagt ccagatattg ctgcaacacc atttatgatt
    11821 ggtatattat tattttccat tgggacagat gcaacttctg caattaatag tgttataact
    11881 aaatcaaaac agttcatttc agctatttca ccttttccca tgactctaag tgcaattagc
    11941 actgttatgt ataatataat acttcttatt aatactactg tcatatctat caattactcc
    12001 tttaaaaaat atttacactt agttagtata tcctatataa aaaatttaat tcaaagtata
    12061 aaaaacctta aataattgga ttcaactatt taaggttttt ttgataattt taatattaaa
    12121 ttttttatgg attttctgtt acttttattt attttaataa cagattcaac aaaactcttt
    12181 ttatctccta attttaagat aaaatcagga tattcttcaa attcattgag ttttattaat
    12241 ttgaaagaag aagatagatt tttaaagtta ataattttag agttattcac taatacactt
    12301 ctttttttaa aataaatttc ttttttactt atatttagta tagttaatat ttgtttaaga
    12361 tatattatta tatcttctgg agttctatca aatttgagtt caaaattttc atcttcaaag
    12421 tagggaatat aatataaagg tgttttgaga gcaggtaatt tattatataa ttcttcaaga
    12481 atatcgatat ttttagggga gttaaagaaa aagcatttac atacattcat taaatccaca
    12541 gcatctgaaa gtgagttatg tttaatatct ccttctacag aaaaaatttt tttcatattc
    12601 agtaaagata tttgcttaga taagattcta ttattgtatg taatatgttg agatataaaa
    12661 ggttgaatgt caatcatcat attaaataac tctaagcatt tacctgtata tttatatact
    12721 ctaaatgaag ttagaaggcc agttatatca aaatcacccc aattatatat tgtaacatca
    12781 tcaaatttac aaaaccattt ataaaaatca tccataacat ataaaagatt aggagcatta
    12841 ttgatatcta gttggttcaa tttggttaaa tttttacatt tatttgaaag tattttattg
    12901 tattttggct taactaaaga gtaataatta tctattgtat taaattcgtt atcaactaaa
    12961 actccaccaa tagaaattaa ttccgcacca ttatattctt ttggtttatt tttattatca
    13021 tctagtatat taaattcaaa gtctataaat aacttgtatt tcataaatct aaagcacatc
    13081 ctcaggtaaa ttatttattg agcctaagca tcataagaat caatagatat aatgactcta
    13141 aacatcaaag gttcattaca acttttattt atttcataat ttaattcaaa taaatctttt
    13201 aagatataat ttataagtat tctttcccaa cccattttta aattaacttt agagtctatt
    13261 aatatatttt ctatcttttt aaatatttct atatttgctg gtattatact gagctcaata
    13321 ttacttttaa acgggttaga ctgtaaatct gttataagta tattttttaa ttcctctgta
    13381 agttcagaaa ttaaactatc acctatgtat ttttttatga tttcctctct aatttctttt
    13441 aaatttagca atattagtac ctgctactta catagtagct tttcctttcc ttttaatact
    13501 attattcatt tttgaatctt atttagatat attttaagat taaaagtctt tagctatata
    13561 attttttacc catttttaac ttatattaac atattacagg cttatatctc caccctgctt
    13621 acattgagga tggagtatat tgcctatttt gataaaaatg ataggttgtt atttgcctat
    13681 tcctttttct gataattttt ctaacatatc tttggtcatt ttatctaaat cataactaaa
    13741 cttaaagttc cattctttta ctgcactact actgtctaga gagttaggcc aagaatcagc
    13801 tatactttgt cttacagggt ctacatcata ttctatcaca aaatcaggaa tatatttttt
    13861 tatagaatca gctatttctt caggagaaaa gctcatagca gtaatattaa aagcatttct
    13921 atggatgagt ttatcagctg gagcttcgat taaatccact attgattgaa gtgcatcagg
    13981 catatacatc atatccattt ttgtaccttc tgctatgtaa gatttatatc tcttattttt
    14041 taatgcctca taatatatat caactgcata atctgtagtt cctccaccag gaggcgtaac
    14101 ataagaaata agacctggaa atctaacacc tctagtgtct actccaaatt ttgagtgata
    14161 ataatcacat agtaattctc cagaaacttt agtcacacca tacatagtat taggtctttg
    14221 taatgtatct tgaggagtca tattttttgg agaattttca ccaaaagcag caattgaact
    14281 aggtgtaaaa aatttacaat ccaattcttt ggctatttca agaccattta ttaatccatt
    14341 catatttaag ttccaagctt ctagaggttt actttcagca actgcagaaa gtaaagatgc
    14401 tagatgaatt atagtatcta catcatattt ttttgcaatt tcaaaaaaac gattcttatc
    14461 tgtaacatct aatatctcaa atataccaga ttcacatact ggattacctt cttttactct
    14521 ccttgaacta gcgattacat tttgttctcc atactcattt ctaagcttta ttgttaattc
    14581 tgaacctatt tgtcctaatg cacctgttat aagtattttt ttcaatttta caacctccta
    14641 agggtttaat ttatgtagta ctacttattt ttattttagc aaatcttttg tttaaataca
    14701 aagaattaaa gataataata tacgacttaa ttgaatgaag tgcagtaagt gcctaaaaat
    14761 ttaaagctaa tatataatgg tatattgtat aacaataaaa gagtagatta aattattata
    14821 tatagattgt gtgactaagt cacagaaaat agagttaatt taatatataa taaaagcata
    14881 tcaagtaaag ctttaaatta aagtaacttt atataaaaag taatataaat tgataaaatt
    14941 ataaatttat ttatagtgaa tataggttgg attttataga tacaaaaata gtatatatga
    15001 tatgtagacc attagcatgt ttaaagtagc aaaacatata aaataaaatt tgaaaggaag
    15061 tataaaaatg acaagaccat caatatatca tagccaagga tacacttgtg cagaggcatt
    15121 aataaagtct tataatgagg aacacaacac agatatacca atctcaatag gaagtggtat
    15181 gggggttgga atgaatgttg gaagtgtttg tggagctgta aatgctgctg ttgttataat
    15241 agggtattta aatgggcgaa atagtaattt agatgaaaat atagcaagga agtattcaag
    15301 agagctattg aatagagtaa gaaataaata cagctcagaa atatgtgtat ctcttaaaaa
    15361 aaataaagta acttgtgaag aaataataaa tttcacatat gatgctctaa atgatatgct
    15421 aaaaaatcaa aaataattct aagaaacaag tattttacat tcgatagaat acttgttttt
    15481 ttatgatatt tttaataagt attagtttat tataattttt aaat
//
LOCUS       DAEPXW010000093        15002 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.095, whole genome shotgun sequence.
ACCESSION   DAEPXW010000093 DAEPXW010000000
VERSION     DAEPXW010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15002
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.095"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            57..764
                     /locus_tag="KRM55_002896"
     CDS             57..764
                     /locus_tag="KRM55_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBH1595113.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(906..1742)
                     /locus_tag="KRM55_002897"
     CDS             complement(906..1742)
                     /locus_tag="KRM55_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1595114.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMINVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSKAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            1930..2835
                     /locus_tag="KRM55_002898"
     CDS             1930..2835
                     /locus_tag="KRM55_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBH1595115.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            2844..4028
                     /locus_tag="KRM55_002899"
     CDS             2844..4028
                     /locus_tag="KRM55_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595116.1"
                     /translation="MEIRYAKEEEIESIKDIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            4143..5444
                     /locus_tag="KRM55_002900"
     CDS             4143..5444
                     /locus_tag="KRM55_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBH1595117.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            5398..6441
                     /gene="holA"
                     /locus_tag="KRM55_002901"
     CDS             5398..6441
                     /gene="holA"
                     /locus_tag="KRM55_002901"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBH1595118.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(6628..6894)
                     /gene="rpsT"
                     /locus_tag="KRM55_002902"
     CDS             complement(6628..6894)
                     /gene="rpsT"
                     /locus_tag="KRM55_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBH1595119.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            7490..8011
                     /locus_tag="KRM55_002903"
     CDS             7490..8011
                     /locus_tag="KRM55_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595120.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            8045..8821
                     /locus_tag="KRM55_002904"
     CDS             8045..8821
                     /locus_tag="KRM55_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1595121.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            9163..10116
                     /locus_tag="KRM55_002905"
     CDS             9163..10116
                     /locus_tag="KRM55_002905"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBH1595122.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            10134..11153
                     /locus_tag="KRM55_002906"
     CDS             10134..11153
                     /locus_tag="KRM55_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBH1595123.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            11184..11435
                     /locus_tag="KRM55_002907"
     CDS             11184..11435
                     /locus_tag="KRM55_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595124.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            11717..13522
                     /gene="lepA"
                     /locus_tag="KRM55_002908"
     CDS             11717..13522
                     /gene="lepA"
                     /locus_tag="KRM55_002908"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBH1595125.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            13671..>15002
                     /locus_tag="KRM55_002909"
     CDS             13671..>15002
                     /locus_tag="KRM55_002909"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBH1595126.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYT"
BASE COUNT         5981 a         1549 c         2480 g         4992 t
ORIGIN      
        1 aaattttcta atacaaaaca ttatatattt agataaaaat ctaggagtgt ggaaagatgg
       61 aaaataattt tacaacgaga actagttttc tagttggaga tgatgggata aaaaaactta
      121 ataattcaaa tataatagta tttggagttg gaggagttgg tagttttact gttgaagctt
      181 tagcaagagc tggagtaggc aatattacta ttgtagattt tgatgatgta gatataacca
      241 atataaatag acaaatacca gccctacatt caactgtagg aagatacaaa gttgatgtca
      301 tggaagaaag aatattagat ataaatccta atatcaatat aaaaaaaata agaagtcttt
      361 ataataaaga tactagtgac gaaatactaa ctgaaagata tgattatgtt gtggatgcga
      421 tagacatggt aagttccaaa atacatctaa ttgaaacttg tgaaaaaaaa ggattgaaaa
      481 taataagttc tatgggtatg ggaaataaat tagacccaac taaaatagtc gttacagata
      541 tacacaaaac aagtacttgt cctctagcta aagttatgag gaaagaactt agggatagag
      601 gtatcaaaaa gttaaaagta gtatattcta ctgaacaacc aatagaactt aagaagaaag
      661 taatgaatgg tagaaaagta acacctggta gtgtatcatt tgtcccatct gtaggaggtt
      721 taataatcgc atctgtaata gtaaatgaac tattaggaca ataagtttta aatattttaa
      781 tttataaatt ttatataaaa atttgaaggc tagaagcatg aatacaaagc aattttatat
      841 tcatactttt agcctaatta ttttatatta ccttatttta tgtagttgta gttttatttt
      901 ttagattatg tatctatttc ataattatat tttgtaaata taatttctcc atcactataa
      961 aaaacaatat ctcctattct atctgttcta taaattgata catggttttg ttttagatta
     1021 ttaataacct ccctatgtgg atgaccatat tgatttttat atccacatga tattgcagct
     1081 atatctggac taattttttt tataaattct aaagatgaag aagaattact tccatgatga
     1141 cctattttta taaaattaat attatttaat ttaaaagaat gtaaaatttc tttttcattt
     1201 tcttcttcag catcacccat aaataaaaaa gaattatcat taaaagttaa tttgaaaact
     1261 atagaattta aattagattc ttcttgtata tatgatggac ttaatacata tatatttata
     1321 ttgttatcta tgtttaaaac atcattttta tagagatgct gaatagataa gtttttatcc
     1381 gtacaagaat ttattagatt ttgataagcc ttactatcag ttgattgttc aggcatatat
     1441 atggagttta cattaaattt ttttataata ttatcaagac ttcctatgtg gtctgaatct
     1501 ggatgagttg ctattataat atcaatagtt tttattcttt tttgtctaag ataactaata
     1561 attatatttt cgctatcttc atcacctcca tcaattaata tattcttatt tgtgggtgtt
     1621 tgaactaaaa tactatcacc ttgtccaaca ttaatcatat gtatagatag tagagatttt
     1681 ttgtcacagc cgattaaaag tgatattata ataagtattg ataaaaaaat tttatttctc
     1741 aataaaaaat cactccattc attacatgtt tatataaatt tatgatgggt aatataagat
     1801 atatatgact tattatattt tatattttaa acaatataaa tgaaattaat accataataa
     1861 aattggagtt ttttatatat acaaaataaa atttttaaaa ttaagcaata aaaaaggtag
     1921 gaggatttta tgtttttcaa agatattgaa ctaaattcaa aaaaagagtt agacccatat
     1981 tttgatttag tagattatga agcttgtgag tactgtttta gtactttata tatgtggcaa
     2041 catgtttata agacaggata ttatataggt gaagattttg ccgttttagt tggggaatac
     2101 gaaggagata gcttctcaat attaccactt gctaaaaaag ataaacttcc agaagttgta
     2161 gattttgtcc ttgaatattt ttctaaaaat aataaaaaaa tatacttaag aggtattact
     2221 actgaagtag tagagttttt aaaagaaaaa tatccaggta gatttgagta tatagaagaa
     2281 agagatttat ttgactatat ttatgatgca gaaagtttaa gaactctagc tggtaaaaag
     2341 aatcaaaaga agagaaacca tataaactat ttcttaaaag agtatgcagg tagatatgaa
     2401 gctaaattat tagataaaga aaactttgat gagtgtttag tactaatgaa ggaatgggaa
     2461 agtaataagg aagaaaataa tgaatttgat gaaagtatgg atgatgaatt aataggtatc
     2521 aaaaagatat ttaaccatta tgacatatta aaagataagg taaaagtgtt tggtgtttat
     2581 gtagatggaa aattagaagc ttttagtata ggagagcttt taaatccaaa tatggcattg
     2641 attcatatag aaaaagctaa tcccgatata agaggtctgt atccatttat aaatcaacaa
     2701 tttttggtaa gtgaatttaa ggacgttgag tttgtaaata gagaagaaga tttaggtatt
     2761 gaaggattaa gaaaagctaa actttcttat catccttgca gatttgttga aaagtacagt
     2821 gttagggagg cttaatagac tatatggaga ttaggtatgc taaagaagaa gagatagaaa
     2881 gtataaaaga tatttggagt tattgtttta acgatacgga gagttttatg aagtactatt
     2941 ttaatgataa atataaatct gaaaatactg tagtagcttt agatgaagga aaaattattt
     3001 cttctcttca gctaaatcag tataagttat tactaaatag caaggtatat aatacatcat
     3061 atgtggtagg agtttctaca cttccagagg gaagaggagc tggatatatg aacaaagtaa
     3121 tgaaatttac tttaaacgaa ttgtataaaa aagggcaatt agtttctata ttgatgccta
     3181 ttgactatag actttataga agatttggat atgagcattg ttacgaccag attgaatata
     3241 ctattaacac agatgattta aaaaatttta agtcaagtgg aaaaatgata aagtctaatt
     3301 tatcacaaat tgatgatttg atacaaatag atagaacttt tttaaatgag gttaatggta
     3361 atgtgttaaa agatgaacat tattatgaaa acttatttaa agagattcaa agtgaagatg
     3421 gatttttata cattcatgaa ggaaatgaaa aagatggata tatagtttat tttcttcagg
     3481 aagataaaat gtttgtcaga gagttatttt ataaaaatat agatgccctt aaatcaatgc
     3541 ttaaatttat atataatcac aatactcaat gtaagatagt tactatatct actcctacaa
     3601 tagataagat aaggtttata ttagacaacc ctaaagatag tgatataaaa ataaaacctt
     3661 ttatgatggg aagagttata aatgtaaaga agtttattga agatatagat attgagaagg
     3721 atattaatag ctcatttaat ttattaatag aagacaagtt tatagatgaa aataatggtc
     3781 tatttaaaat ttctatacag aataagaagg tatctgtaga gcagttagat aaaaaaggtg
     3841 cagaaaagcc tcaagaagat tttgatatta aattagatat aaatacctta acacagttat
     3901 cattttctta tatagatgta aatgaagcta ttttcttaaa tgatataaaa gatgtttcag
     3961 aagaaacact agaaacactt aattgtattt tttctaaaaa aaataactat ataaatgaat
     4021 atatataggt agagtacgtt aaaagattct aaaaatcttt tgacgtattt ttttgtttag
     4081 ataacaattt atcttgttta aaaattttct atttgaaaat aatctaaata atatactttt
     4141 atatgggagt gattataatt caaataagaa gaccattatt aattatatta atgtttgtgg
     4201 tagctatatc atttatcatt acaaataaca caaaaaacga cgaagaactt aatgataaga
     4261 taataactat acaaggagtt gtcaaaggaa aaattgaaaa gaaaagatac aatcagtaca
     4321 aggtaggggt ttttctaata aatgattata caaaaaataa aaatttgaag attggtcaga
     4381 aagttaatat tacaggtaaa ttcaaaagtt tagataaaat gaagtatgat gattttgatt
     4441 atggaaggta tataaaaagt actggatata aaggtatagt gtatataaat aactataaaa
     4501 ttattgataa aaataaactt tactctttaa taggggaaat aaagttttat attagtaaaa
     4561 cttataggta cttatataag aaaaactcag attttataaa ttctatacta ttagcagaag
     4621 ttgaaaattt gactgaggaa caaaaagaaa tttttaccag aactggaact agtcatgtaa
     4681 tatctatatc aggtcttcat acaggaatat tatgtgtaat tatatccttt ctattaagag
     4741 gtataaataa attgtataaa ttattaatac tgtcgatttt tataacttta tattgtataa
     4801 tggtaggtgc gtctccatcc ataattaggt ctatagcatt tgttatgatt ttttatttat
     4861 caatatttat tgatagaaag aaagatggaa tatcggcatt gtctctaatt gggataattt
     4921 taattatgaa taacccctat gttatatata atgtaagttt tcaattgtct tttttagcta
     4981 cactttctat attaatattc tataataaaa taaatagtat tataaaatta agtatggtat
     5041 cattgacaat atcatcaaat atattaactt tacctataat ttattataca tttaaaggta
     5101 taccattgct ttcaattata ggaaatttaa ttatagtgcc atttgtggga gtaataatgt
     5161 atttaagtat tgcaagttta atcgtattta aagtaagtgt agtaatagct aaaattatat
     5221 ctttttttaa tagtacattt atagaaagca tatttttttt actagaaaaa atcagcaatt
     5281 taagttttgc atacattaat atagaaaatc ctaaatttta tattgttgtt atttattaca
     5341 taggagtgtt tttttacata ttttacatag aaggaaaaga gataaaggag caagagaatg
     5401 aattacaagg atattataag gaatgtaaaa gagaaaaact ttgaaaaaat gtatcttttt
     5461 tatggaagag agtattattt aattgagaat gcaataaaag catttaaaga tagtctaaac
     5521 gagggaatgc ttgattttaa tttagatata atagatggga aggaaatagt cttaaatcag
     5581 cttataagct ctatagaaac acttccattt atggatgata ggaagatagt aataataaaa
     5641 gactttgaac tattaaaagg aaagaaaaag aattttacag atagtgatga gaaatactta
     5701 atagagcatt tagacaatat tccagacacc acaactatag tttttgttgt atatggagat
     5761 gtagacaaaa gaaaatcatt agttaagaaa ataggaaaca atggaattgt ttttgattgt
     5821 gataagcttt ctgatatgga tttgtttaaa tggataaaaa aatcttttgc tttaaatgat
     5881 gttataatag ataattctca aatcatgtat tttattgaac aagaaggata cagagataag
     5941 agtagtgaaa agacattatc tgatttagaa aatgaaataa ataaaataag ttcatttgtt
     6001 ggtaaaggga ataatgtaac caatgatgta attgataaat tatctcaaaa aaaagttgag
     6061 aatgatatat tcaaattaat cgattatatt ggagaacaaa atgcttctaa tgcaatgaaa
     6121 atattaaatg atatgataca agaaggcgaa tctgtattag gtatattttc tatgatagca
     6181 agacaattta aaataattat gcaagtaaga cagttacaac ttgatggata ttcaacaaaa
     6241 cttatagctg ataaattaaa aatgcatcaa tttgttgtag gaaaagcatt aaagcaaact
     6301 aaaaattttt ctgatgatat aattgtggaa atattaaact atatattaga aagtgattac
     6361 aaaataaaga caggtcttat aagagatact ttagcagttg aaatgttggt tagtagatac
     6421 tgtaaaagag aagcaattta aaaaatctat atattaataa aaaataaata gcaagatatg
     6481 ttatagttca gagtagatgt aagctaaatt aagtttgata tacaatcaac tataatatgt
     6541 ctaactattt attttttatt gtataaattt acaaaataaa aaacccctac ataggggtta
     6601 ttatatataa gaaatataaa ctggtaatta agcgttcata ccgtttaatt tttgagctaa
     6661 tttagctact tttctagctg cagcattctt atgtatagtt cctttagaag ctacttggta
     6721 tattcttttt tgagcgtatt ggaacttagc aacagcatcc tctctgtttc cagctgcaac
     6781 agcatcttcg aatcttctta ttgcagtttt tatttgagat tttctaactc tatttaaagc
     6841 agttttcttt tcgataacac ttattctttt cttagctgat tttatatttg ccaccgtgtt
     6901 cacctccctg tattttttta tcatattcat cgtcaacata ttagatttta acagaaataa
     6961 atctaaaaat caaggattat tatttatata ttttaataat gttttttatt ttgatttttt
     7021 agactgtaaa ttgtgtataa ataatttgca atatcttgtt tttaaattgg tatattttgt
     7081 gttttaaata ttttgacata tataattaat atttcatttt gtaacaaata tttgagataa
     7141 tacaaactat taacatacat tttgatagta tttccaataa ttataagata atacaagaaa
     7201 ttactcattt ttgtaaattt aatgaaaaat tataaaaata taaatttata tgcttaatta
     7261 agataatttt tccaataatc aagataattt ttttcattag tatgtatgat agatgcatca
     7321 aacaatataa ctaatatgtt agaaggttat atgtaattaa tgtcagtgtt tatatagaat
     7381 agcatttgta gcatttatta tagttgtaat tactatttat atcatagact tgaatagtct
     7441 aaaaaaatag actataatat ttttatagac taaagaaagg gctgataaga tggacatagc
     7501 aaaactaatt ttaaatcctg caaggcttcg tattttacaa tatattcgac tttatggcag
     7561 tgttcgtaca tctgatattg taaagtattt aaatgatatt cctcgtgcaa cagtttatca
     7621 ccatgtaaaa attttagaag agaacaatat gattgaagta attaaagaaa atcgtgtgcg
     7681 tggtactatt gaaaaggttt atgcactaaa ggaatataca acatctatgg aaggagagac
     7741 cttcgttgca ctttctacag cattttatgt aggtctgatg caggaaatga atgaatactt
     7801 tagcagaaaa gagcaagacc ataaaaagga taatgtattt ttctcttcag cattactata
     7861 tatgagtgat aatgaatatg aaaatcttct taaaagtata gctgatttat tgaaaccata
     7921 tatagaacaa aaacctaaat caaatctaaa acttagaaaa ctttcaatta tatcttctcc
     7981 acctgtagct gataatgata aaacaaaata acatgcaacc catttttata aaaggaggtt
     8041 atatatgaaa tttcatgagt ttggaaataa aaacagacca catattatgt tgattcatgg
     8101 gggagggaat gcatggtgga actatttgcg acaagcagaa gttttgtcta acaaatatca
     8161 tgtgatactt cctacattgg atggtcatgg agaagaatat gaaacaacat acatttctac
     8221 agaggataca gcagataagt tgatatcata tatagatgaa aattgcagtg gacatctttt
     8281 cgctttgtgt ggggtatcac ttggtggtca aattgtcatg gaacttttat ctcgaaaacc
     8341 taatattact aaaaaagcaa ttattgatgg tagtatttgc tacccaagac ctcttatggc
     8401 aaggttttgt attgctggta ttcgattttt tggaggactt ttgtttagtg agaaggcttg
     8461 tcgctttcaa attgctatga tgccaaaatt gttacctgaa aatatgcaat atccagatga
     8521 aataaaagcg tattatatga cagatatgcc acatgtaaga aaagaaacat tctataatat
     8581 gtatcgtact tacatgatga actatacact taaagagaat gttaaaaaaa ccacagcaca
     8641 agtaatgtac tggtatggag aaaaagaaat gaagtgtgtc aaaaaatctg caaaactgtt
     8701 tcagtcttat gtgccctctt gtgagattta tgaagctaag agctataatc atgggtattt
     8761 atcactttat cttccaaatg aatggttgga aattgcagaa ccatttttcc aaaaggaata
     8821 aaggtgttag gtgattattg tataattatt gctgtttttt tatatagtaa ataaattagg
     8881 tataaatata aaaaattatt ttagttaata tattagtgaa agcttaatag gaaaattata
     8941 aatagattaa aggtagcacc tatataaata gttgctacct ttttctgttt gtaaataaat
     9001 gatagataag aaggtttact gacaaatcac tgactaaacc caattttctt acattgaaag
     9061 ccttaatttt acttgtttta aataaattta caatttcttg ttataaaata ctaaattttg
     9121 ttaacaatta taattagcat ttaatttata ctggaggttt atatgattag tgtaagaaca
     9181 gatttagctt tagaagctag tgaaatgtgt gaaaagtctc aagaaggaag tagtattcct
     9241 ggtgtaaaaa tagaaactaa agaattagaa aattgcattg taactaaagt tgaagtaata
     9301 gacaggcaag gcgcagagat aatgaataaa gatataggaa agtatataac tctggaaagt
     9361 aatcttatga agtttgatga tgatgagtca agagaagaaa tgataagtta tttaaaagag
     9421 gagttagtag atatatttgg ccaagacaaa aataaaaaaa ccctggtaat tggtcttgga
     9481 aatagaaata ttacttctga tgcgttagga ccaaagagtg tatcaaaaac acttgtaact
     9541 agacatcttt ttaaaaatta taataaagac tatgatgatg atttcactga ggtatcagct
     9601 ttaagcccag gagttatggg tgttactgga atagaaacta gtgaaatagt aaaatcattg
     9661 gttgagaagg ttaagccaga tagagtagta gcaatagatg cattggcttc aagaaaaatg
     9721 gagagagtaa actctactat acagatatca acagcaggaa tatcacctgg tggaggtgtt
     9781 ggcaatacta gaaaatctct aactaaagaa actttaggcg tggatgttat tgcaataggc
     9841 gttccaacgg tggttgatgc agcaactctt acaatagatg tcttagatat ggcaatagac
     9901 aatttaatag ctcaatcaga agaaacagaa agtttttatg aaatgttgaa aaaacttaaa
     9961 gaagaagaaa aatatcatct aataaaagat tcgttagacc catatgacaa gaacttaata
    10021 gtaacaccaa aggatataga tgatacaatc gaaaatctat ctataataat aagtgaaggc
    10081 ttaaataggt ctttacatcc aggtagattg gtataaaata aggaggagca attatgttta
    10141 aaaaatgcat taaagtagta accttgactt ttatattagt atgcatttta ccaggaaaat
    10201 cattagcttt gaatcaagat gattttttaa agtttttagt aaattcatct tatccagaag
    10261 ctaaagtcga aggaaatgat acagaaaata aaaagaataa taaaaataaa gaaacaagta
    10321 aggaaaataa ggaagaaagt aaagaaggaa acactaaatc taaagatgca agtaaagttg
    10381 ataataaaaa agagagtgaa aaagaatata taaaacttta tgttggtaaa gaaaatgttc
    10441 cagatattga gtcaaaaaat tcagacacaa ctgaaactaa cacaacatct agttcagatt
    10501 ataaggatga tttaagagta accaaagaaa atccaagaat tttgatatat catactcatg
    10561 gatgtgagac ttattcaaat tcacctgatg gaaattatca ttcaagagat aagaaaaatt
    10621 cagtaatgga agtaggaagt gcattaacta gtgctttaga tagcaaagga tggggtgtag
    10681 tccatactac taaataccat gactatccat cttataataa ctcttatgca agtagcttaa
    10741 aaacaataca aagtatatta cctaaatata actcagtgga tatagcgata gacttacata
    10801 gagatgctag ggatttaact aatccagcca ctaaggaaaa agaccattta aaatatacaa
    10861 ctatgataaa tggagagaga gtatcaaagt tcttctttgt tgtaggaggt aaaaatacaa
    10921 atagaaaaca acttagagct ttagcagaag atataactgc ttttgctgag aaaaagtatc
    10981 ctggtctagt atctccaata gtagaaaaag actatgctag attcaatcag tttgcagtta
    11041 agaatcatat gttagtagaa atagggaata acgcaacaag tgtagaagaa tctaaggcta
    11101 ctacaaagta tttagccgag attttggatg aatattttaa acaaaaaaat tagagcttta
    11161 agttataatt aggagcatgc taaatgagcc gattagaaaa aaatatagaa agtaaaagta
    11221 aactaagaaa atacaagtat attatgagaa tcttattttt gattactatg attatatgta
    11281 catcagtttg tgtatttata gtggacagta atgcaaaaag tatgctagga atgaaacaat
    11341 atgattttcc aagtattaaa tttgatataa caaaatttga ttttgacata ccaaattttg
    11401 atatacatga aatcataaaa aaatttaata agtagtaata agtgaataag gtttattgat
    11461 taaaataagc cttattttag ttatatattt ttaatgtata aaataaaaat tcattaactg
    11521 tattttatag gatttacttt aagtttatga tattatataa tatttagtgt tagacttgat
    11581 aatccacata taatgtggat aattttgttt agtgccaatt agtttatatt caaaaatttt
    11641 aaatttggta tataaagagt ttttagataa tgtaaaataa taactataag aataatcaag
    11701 aggagggaat tttaaggtgg acaataaaca aagtagaact agaaatttta gtataattgc
    11761 acatatagac catggaaagt ctaccttagc tgatagatta atacaacaaa ctgggcttgt
    11821 tagtgaaaga gacatgaaaa gtcaattact tgacaatatg gaccttgaaa gagaaagagg
    11881 aatcactata aagcttcaaa acataagatt aatgtataaa gcgaaggatg gaaatgaata
    11941 ttatttaaat cttatagata cacctggaca tgtagacttt aactatgagg tatcaagaag
    12001 tttagctgca tgtgaaggag cactattagt agttgatgca gctcaaggtg ttgaggcaca
    12061 aactttagcc aatgtttatc ttgctataga ccaagattta gaaatattac caataataaa
    12121 taaaatagat ttaccaagtg caagaccaga ggaagtaaaa aatgaaatag aagatttaat
    12181 agggcttgat tcaagtgaag ctcctcttat ttcagctaaa actggtttaa acatagaaga
    12241 tgttttagaa gatattgtaa aaaatgttcc tccacctaaa ggagataatg aagctccatt
    12301 aaaggcatta atattcgatt cttactatga tgcttacaaa ggtgttgtag cttatgttag
    12361 agtatttgaa ggaactgtta aaaagggtat gacaataaaa atgatgaata ccaataaaaa
    12421 gtttgaggta actgaagttg gtgttatggc tccaggtcaa actgaactta gtgaattatc
    12481 agcaggtgat gttggttata ttgctgctag tataaaagat ataagaagtt gtcgtgttgg
    12541 tgatacaata acagattcaa ataatcctac agaagaacct ttaccaggat acaaaaaagc
    12601 tactccaatg gtatattgtg gtatatatcc aggagaagga gaaaagtatg agaatgttag
    12661 agatgctctt gaaaagcttc aagtaaatga tgctgcactt gaatatgaag ctgagacttc
    12721 agcagcacta ggatttggtt ttagatgtgg tttcttaggt cttttacata tggagataat
    12781 gcaagaaaga cttgagagag aatttaacct tgatataatt actacagctc catctgttat
    12841 atatagagtt acaaaaatgg atggagaggt tgtaatgata caaaatcctg caaacttacc
    12901 agaaccatct gagataaaga tgatagaaga gcctatagta aaaggagata taatagttcc
    12961 taaagactat gtgggtgttg ttatggagct ttgccaggaa agacgtggaa atatgttaaa
    13021 tatggaatat atagatgata gaagagtaat gcttcactat gaccttcctc tcaatgaagt
    13081 tgtttacgat ttctttgatg ctttaaaatc aagaactaga ggttatggtt ctcttgatta
    13141 tgaggttaaa ggttatgtag catctacact tgtaaaactt gatatattaa tcaataaaga
    13201 gcaagtggat gcacttagtt ttattgtcca tgagacacgt gctttcccta gaggaaaggc
    13261 aatgtgtgag aaattaaaag gagaaattcc aagacatcag tttgctatac caatacaagc
    13321 tgctgttggt aataaggtta ttgcaagaga aacaataagc gctctaagaa aagatgttct
    13381 tgctaaatgt tatggtggag atatatctcg taagaagaaa cttcttgaaa aacaaaaaga
    13441 aggtaagaag cgtatgagac aaattggttc tgttgaagtt cctcaaaaag catttatgtc
    13501 tgtgcttaaa ttagatgagt aaatccttat aaatttagat aaagatattt aaaagctaga
    13561 gtgattttag aattatttct aaattagtct agctttttta tggtatattt taagtaaact
    13621 catagagaat ataagtaaga atattaaaga agaataaaaa ggtgatattt atgattaata
    13681 tagaaattcc taaaaaagta gactatataa ttaaagaatt agaaaagaat ggttatgaag
    13741 cttatatagt tggaggatgt gttagagatt gtttattaga aagagttcca aacgattggg
    13801 atataacaac tagtgctaga ccagaagtgg tagtagaatt atttgaaaaa acaattccaa
    13861 ctggtataca acatgggact gtaacagtta tgattgaaca tgaaccattt gaagtgacga
    13921 cttatagaat tgatggaaat tatagtgatg gtagacatcc agattcaata gaatttacaa
    13981 ataacatagt taaggacttg tcaagaagag attttactat caattcaatt gcatacaatt
    14041 caaagacagg attagtcgac ccatttaatg gctatgaaga tatacaaaat aagtatatac
    14101 gttgtgttgg aaatccagta gatagatttg aagaagatgc acttagaatg cttagagcag
    14161 ttagattttc agcacaactc aattttaaaa tagctgaagg tactaagcaa agtattcata
    14221 aaaaagcaga tttgataaaa aatgtttcta ttgaaagaat ccagacagag tttaataaaa
    14281 tattagtatc tgattcatct aaattaaact tattaaaatc aacaggtttg ttgaaattta
    14341 taattcctga aatatgtgaa ttagaagatg ttactcaaca caatccatat cacatctatg
    14401 atgtacaaaa acatacttta atagctacag aagtaattga agatgaactg tatttaaaac
    14461 ttacaatgtt gtttcatgat ttaggtaaaa aagtaactaa aacaactgat aaaaatggtg
    14521 ttgaccattt ttatactcat agtagagaat ctgtaaagat tgcaaagaag attttgaaaa
    14581 gacttaagta tgataattat actattaata aagttttaat attaatacaa tatcatgatt
    14641 atagaataga acctaaaagg aagataatta aaaagttatt aaataaactt gaagatgttg
    14701 aattatttga agatttaata aaagttaatt gggctgatac acttgcaaaa aatccaaagt
    14761 atgcaaaaca aaagatatta aatcttattg agtgtgaaaa agaatttaaa catataataa
    14821 atcaaaagga gtgctttaat cttaaagatt tagctattaa tggaaaagat ttgatatcta
    14881 taggtataaa accaggtaaa gatataggat atattttaaa taagatgctt gaaatagtca
    14941 taaataatcc agagttaaat gaaaaagaaa tactaaaaga aaaagcatta aatatatata
    15001 ca
//
LOCUS       DAEPXW010000094        14462 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.096, whole genome shotgun sequence.
ACCESSION   DAEPXW010000094 DAEPXW010000000
VERSION     DAEPXW010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14462
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.096"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            161..301
                     /locus_tag="KRM55_002910"
     CDS             161..301
                     /locus_tag="KRM55_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595127.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(476..796)
                     /locus_tag="KRM55_002911"
     CDS             complement(476..796)
                     /locus_tag="KRM55_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH1595128.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(916..1653)
                     /locus_tag="KRM55_002912"
     CDS             complement(916..1653)
                     /locus_tag="KRM55_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBH1595129.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCYNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1868..3691
                     /gene="acd"
                     /locus_tag="KRM55_002913"
     CDS             1868..3691
                     /gene="acd"
                     /locus_tag="KRM55_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBH1595130.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3906..8204
                     /locus_tag="KRM55_002914"
     CDS             3906..8204
                     /locus_tag="KRM55_002914"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBH1595131.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8408..8869
                     /locus_tag="KRM55_002915"
     CDS             8408..8869
                     /locus_tag="KRM55_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBH1595132.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8899..10053
                     /gene="nusA"
                     /locus_tag="KRM55_002916"
     CDS             8899..10053
                     /gene="nusA"
                     /locus_tag="KRM55_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBH1595133.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            10060..10341
                     /locus_tag="KRM55_002917"
     CDS             10060..10341
                     /locus_tag="KRM55_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBH1595134.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10331..10642
                     /locus_tag="KRM55_002918"
     CDS             10331..10642
                     /locus_tag="KRM55_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBH1595135.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10664..12604
                     /gene="infB"
                     /locus_tag="KRM55_002919"
     CDS             10664..12604
                     /gene="infB"
                     /locus_tag="KRM55_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBH1595136.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12647..13027
                     /gene="rbfA"
                     /locus_tag="KRM55_002920"
     CDS             12647..13027
                     /gene="rbfA"
                     /locus_tag="KRM55_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBH1595137.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            13008..13685
                     /locus_tag="KRM55_002921"
                     /pseudo
     CDS             13008..13685
                     /locus_tag="KRM55_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
     gene            14325..>14462
                     /locus_tag="KRM55_002922"
     CDS             14325..>14462
                     /locus_tag="KRM55_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595138.1"
                     /translation="MIAVKKAYKFRLYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KN"
BASE COUNT         5782 a         1649 c         2708 g         4323 t
ORIGIN      
        1 ttttaatagg taaaatatcc tattgttttg tagatatatc ctaattatgt caaaaaataa
       61 aaaaattttt atttattaga gtttttggaa ataataataa cagatattat aattaattaa
      121 cagtttttgt aagtatttga caatagagag ggtgtaacaa atgggaataa tagagtcagc
      181 atcaaaattg gctgagatgg ttcatttatt ggctgttgaa aaggggataa ctgatataga
      241 agcatgggat gaagctgtga aagaatacag caaaatttat gaagaaagaa gaaatgaata
      301 gaatgataaa aaatgaaaac ttgatgataa aaaataactt tatttaaaga aattcaattt
      361 ttatagaagt attaaaaata atataaataa aaagatggta tttcaaatgt aagtaaaaaa
      421 tcattttggg ataccatcct tattatttat tttaataata tataagtaat aaatcttact
      481 tatccatatt ttttatgtaa cctctttttt ctaacttttt tatatgctcc ttacgtattt
      541 catcaagatt aataccatat tgttcttcta gcttaaacat catagtaaca catgtctgcg
      601 ctacatccat tagttcctta gcagttttct ttataatatc aacttcatct aaatcattat
      661 tttctccact tagatttctg aatttaccta tacattcagc taattcacct tgttcttcac
      721 ccattttgat aaatgtagat tctagtgttg ggtctaaatt attaagctct ggtaaagata
      781 tagtttttag tttcataaaa gctcctttca agttattcgt atttatacta aaacatcata
      841 acaaaaataa tactaaaaaa aaactttaaa ttcaacataa aaacttacat atataataaa
      901 aatcgtgaaa taaatctata tttgtcttaa tacagcctca tataaaactt ctccaatagg
      961 tttatttatt acaagagaag ctgacttatc atagactgta tttgctttat taataagagc
     1021 aatataatca cctttgtaat aatctataaa acttgctgct gggtacacag ctaatgatgt
     1081 acctcctata atcaataaat cagcattact tatagcagaa attgttttag taatgacatc
     1141 actgtcaaga gcttcctcat aaagtactac atctggtttt actatagaac cacagttgta
     1201 acagtaagga atattacctc ccagatttaa catagattct aagtcaaaaa acttaccaca
     1261 tttagtacaa taatttctat gtacagaacc atgaagttct agcacatttt tacttccagc
     1321 catttgatga agtccatcaa tattttgagt tatgacagct ttaagcttac ccatttcttc
     1381 gagttttgct aaagctatat gagcattatt gggttttgca ttaggatata ttaatttatc
     1441 cttataaaat tcaaaaaatt cttctggata tctaacaaaa aaagtatgtg aaactaattg
     1501 ttcagcagta aattgtttat tgagtttttg gctaaataat ccagtagaac ttctaaagtc
     1561 tggaatatta gattcagttg aaacacctgc tccaccaaaa aatacaatat tattgtgatt
     1621 agctattaag tcttttaagc tatttgcatc catagttaca cctccaaatt attatatata
     1681 aattgtacta catattaggt cgtttatgtt ttattaattt aaataaatat atagtttaat
     1741 aagttaaata aagggaatat aaataaaatg tatacagagt ataaatagac aatatttact
     1801 aaaataacaa gttgtcgtat aattatatta aaattgtttt agtgtataag aagggcgggg
     1861 gaagtacgtg aagaaaaaag cagctttagc aacattggct atgttaccct taggtgtggt
     1921 aaatgcacat gctgatggag atataggtat agtgactata aattatttaa atgtaagaaa
     1981 tgaaccaact gccgaaagta gcatagcctt tgttgctaaa aaagatgata aagttttgat
     2041 taaagactct tctaatggat ggtataaaat aaaagctgaa tctggacaag aaggttgggc
     2101 ttcatcaaaa tatatagcaa aatcaaatag tgactcttta agaacgtcta caaataaaga
     2161 aaaacaagtt atttcaaata gtttaaatat gagaaatgga gcaggtacaa gttacagagt
     2221 aataactgta ctaaaaaaag gtcaaaaagt agaagtaata tcagagagta atggatggtc
     2281 taaaatcaaa tatgatggaa gactaggata tgtatctagc tcttatttag gagacgtttc
     2341 aaactcaact aataaatcaa aaactaaaca agtgaataca acttcactaa atgtaaggag
     2401 tggaccaaat acaagttatg gtttgttagg caagttgcca aaaggaagta aagtagaagt
     2461 aatatcagaa agtaatggat ggtccaaaat aaagtataat ggaaaagatg cctatgtatc
     2521 tagtatgtac ttatcggatg taagtcaaag taattcagac aattctagtc aaagcaatga
     2581 taaaaagaat actgataagg ttgtaaatac agcttcttta aatgtaagaa gtggaccagg
     2641 ttctacatat agtaagttgg gaaaagttta taaaggaagt aaagtaactg tactatcaga
     2701 aagtagtgga tgggctaaga ttaattttaa caataaagaa gcatttgtag taggcaatta
     2761 tttatctacc tcagcagata cttcaaataa taactcaaat agtaactctg ataacagttc
     2821 taatagtaat ggtaataatt cttcatcatc aggccaagta aatggtatgt caggtataag
     2881 tggggctaaa attgattata aatctttgag ttatacttta gaatctcata taagtaaaca
     2941 agttgagaaa gcagcatcag gaggaaatgt gatagctcca agtaatagga aaagtactcc
     3001 aagtcctgag tttagtactt tttcagctca aagaacaagc tcatttgtaa atgcaagttc
     3061 aagtgatata gaatattatt taaatcctaa gaattttaca aatactacta aaggtatgat
     3121 gcagttttta aagattaaca gttatagaga tggtatttca gaatcaagtc ttaactcgta
     3181 tcttaatggt ttatcttcta gtgtatttaa aaaccaggga gcagccttta taaatgctgc
     3241 caagaagtat aatatagatg ttgtatatct agtatctcat gctatgtggg aaactgctta
     3301 tggtaagtct acacttgccc aaggtcaaac attaacatct tataagggac aacctcttag
     3361 taagccagtt aaagtataca atttttttgg tataggagca atagataaaa gtgctaatgt
     3421 ttcaggtgca gaagcagcgt attccaatgg ctggactagt gtagaagcta caatagatgg
     3481 ctctgcaaag tggatatcac aaaattacgt aaatagttct aagtacaatc agaatactat
     3541 ctacaagatg aagtggaatt atgattatac atggcatcag tatgcaactg atgtaaactg
     3601 ggctaatgga atttctggaa ttatggaaaa tttaattggt ctttatggag gaggaagtag
     3661 tttggttttt gaagttcctc aatataagta atacataaat aaaaaatata gactatgggt
     3721 agttttcatt ttatttaaat tatctatagt ctttttgtat ataatttata atctgtaaat
     3781 ttaatgttaa caaaactttt atgttataat attaattcta agtaaatata agtgagtaat
     3841 aggtagaaat agataaaaag tggtaataat atatataaag ataattttga gaaaggagga
     3901 tatatatgga aagtattaag gaatatttgg ataagttaga aattaataat agtggtcttg
     3961 gaaagcaact taaagaagtt tatataaata gagtagttta ttttaaggaa gataagatag
     4021 tttattttta tctaacttct aaagatattg tttctcatga acttttagat aaatttaaag
     4081 aagaattgat gtataaactc gattatttta aagatatgag gatgaagata agatttactg
     4141 gtcttgaaag aaaatccaat aaagatgtta taaaaaaata ttggaataat atattgtata
     4201 tattaaagta tctttgtcca tctattgcag ggtggtataa acaagtagaa tttctttgtt
     4261 tagaagaaga attaaaaata aaacttccaa aaggtatatt ttatgagcga ttaatgaaaa
     4321 aaaatgtaac ttatgtactt aaaaccgtgc ttagcgaaga gttgggatta gatttaaata
     4381 taacaataga aaaagctgtt gatgaaaagg taaataaaga aagactcata agaatcaatg
     4441 atagagaaat ggaagaaaaa attagggctt tagaaattgg aaaagttaat aactgtgaag
     4501 aaaatgaaga ggaaagctat gtcattaagt ctgatgtaga tgaaaattta atctatggag
     4561 ataatgcaaa tgctatgatt gaaaatatag ttgaattaaa tgcatcttct ggaacagttg
     4621 cagttgttgg agatatattt gatgttgaca ctaaagaact taaaaacgga aaaatactta
     4681 tgatagcttc aattacagat tatactagct caataagctg taaacttttt ttaacagata
     4741 caaataagga tggagtactt gaaaatgtta aaaaaggagc atacttaaaa atcaagggtg
     4801 acatagttta tgatacatat caaagagaaa ttagtatgat gattagtggg ataagaaaag
     4861 aaactagaat agagagagaa gataaatcag aggaaaaaag agtagaactc catgcacata
     4921 cacaaatgtc ttctatggat gctatttgtt ctgttaaaaa gcttgtagag cgtgcagcca
     4981 aatggggtca ttctgctatt gctataacag accatggtgt tgtacaagga tttccagatg
     5041 ctatgaatgc aggtaagtca aataatataa aaatacttta tggagtagaa gggtacctgg
     5101 ttgaagatga ttctctcatt atagaggatg caaatgataa agaactttcg cagacatttg
     5161 ttgtatttga catagagaca actggctttt ctaatacaaa tgataaaata actgagattg
     5221 gtgctgtaaa aatagaaaac tttaagattg tagatagatt tagtgagtta ataaatcctg
     5281 aaaaagatat ttcttataag atacaggaat tgacaggaat aactaatgaa ttaattaaag
     5341 acaagccaac cattgaagaa gttcttccta agtttatgga atttgttgga gatagtgtat
     5401 tagtagcaca taatgcagag tttgatactg gatttatatc gcaaaaatgt agggaacaag
     5461 gcttgttata taataacaaa aaagtagata cacttatgtt agcaagagta atgttgccaa
     5521 acttaaaaag acatagatta aatgtcgttg caaaagaact tggtattcct cttttaaatc
     5581 accatagagc agtggatgat gctgaagcta cagcacttat atttaataag tttttgcaga
     5641 tgcttacaga aaaaggtgca aaaactctaa gtgatgtaaa caatatactt ggaaagattg
     5701 attacacaaa gcttagcaca aatcatataa ccttgatagc aaaaaattct ataggtataa
     5761 aaaatttata taaaataatt tcagatgcac atgtaaatca tttttttaga gcaccaagaa
     5821 tccttagaag tgtattaaat gaatataaag aaggattaat aattggttcg gcttgtgaag
     5881 ctggggtggt ttttcaagct gtaaagaaaa acgtgtctga tgaggaaatg aaaaaaataa
     5941 tagatttata cgattatatt gaagtaatgc ctatagataa taatagattt atgattgata
     6001 aaggagaagt aaaggacgaa gaagagttaa gggagttgaa taggaaacta attgatacag
     6061 ccaaaaaatt tgacaaaatt ccagtagcta ctggggatgt tcatttttta gacaaacatg
     6121 aagctgtctt aagaaaagtt cttaaatatt ctcaaggttt taaagtagat gaagaagaaa
     6181 cttatttaca ttttagaaca acagatgaaa tgttggaaga gtttagttat cttggagaag
     6241 aattggcata tgaagttgta gttgaaaata gtaatctgat tgccgatatg gttgaagata
     6301 taaaacctat accagatgat acttatcctc caattataga gggctcagat gtggagttaa
     6361 gagaaatgtg ttacaaaaaa gccaaacgaa tctatggaga cccaatacca gaaatagttc
     6421 aaaaaagact ggatagagaa ttaaattcaa taataagcaa tgggtatgca gttatgtata
     6481 ttatagctca aaaactggtt gcaaaatctc tttcagatgg atatttagtt ggttcaagag
     6541 gctcagttgg ctcatctttt gcagctacta tgagtgatat aacagaagtt aatcctcttc
     6601 cagcacatta tatttgtgaa aacgaagact gtaaatattc attcttttat gaaataggtg
     6661 aatggggctc aggtgttgat ttaccagaca aggattgtcc aaagtgtgga agaaaacttg
     6721 ctaaaaacgg tcatgatatt ccatttgagg ttttcttagg ttttgaaggt gataaggaac
     6781 cagatataga cttaaatttc tcaggaaatt atcagccaac aattcataaa tacacagaag
     6841 aactatttgg agaggggtat gtatataggg ctgggactat aggtactgta gcagaaaaaa
     6901 cagcttttgg atacgcaaga aaatatgtgg aagaaaataa tataagtgta ccaaatgcag
     6961 aagtacttag gctttcaaat ggatgtactg gagtaaaaag aacctcagga caacatcctg
     7021 gtggagttat ggttatacca gactataaag atgtatacga ttttacacct atacagtatc
     7081 cagcaaatga tacttcttgt ggtgttataa ctactcactt tgattatcat tcaataagtg
     7141 gtagaatact taaacttgat atacttggac acgacggtcc taccattata aggatgcttg
     7201 aagatatgac tggaataaat ataacagaaa ttcctttaga tgataaagag actatgtctc
     7261 tatttacatc tacagaagca ttaggtgtta caccagaaga aataaactgt cctataggtt
     7321 gccttgctgt accagagttt ggaactaagt ttgtacgaca aatgttactt gacacaaaac
     7381 ctactacatt tgcagaactt gtacgtatat ctggtctctc tcatgggaca gatgtttggg
     7441 taaataatgc acaagactta gttagagaag atatagttgg attaaaagat gttatatcta
     7501 cacgagatga cataatgaac tatttaatat ttaaaggatt acctcccaaa atgagcttta
     7561 caataatgga gagtgtaaga aaaggtaaag gtttaaaacc agaacacatt gaagaaatga
     7621 aaaaaaataa tgttccagaa tggtatatag gctcatgtaa aaagattaag tacatgttcc
     7681 caaaagcaca tgctgttgct tatgtaatga catcatttag aattgcatat tgtaaagttc
     7741 actatccaga agcattttat gcgacttatt ttacgacaaa agttgaggat tttgatgcag
     7801 atttaattgt taaaggatta gatgctataa aatcaaaaat aaatgaaatt gagtcactgg
     7861 gaaatgatgc aaccacaaaa gaaaaaggta tgttgaccgt tttagaagtt gctcttgaaa
     7921 tgtatgctag aggaataaaa ttattaccag ttgatatata taaatcagat gcaactgagt
     7981 ttatagttgt aggagaaaaa acattacttc caccaatggc agcaatacaa ggtcttggag
     8041 gaaatgcggc tataaacatc caaaatgaaa gaaaaaatgg tgaatttata tcaaaagaag
     8101 atttgagaaa gagaacaaaa atatcaaaaa cggtaataga aactcttact aatcatggtt
     8161 cacttgagaa tatgagtgag agaaatcaat tgtcattgtt ttaagttagc ccaaaaagtt
     8221 gcaaataaaa gaattttatg atatcatagt atagaaaata gtatactttg cagaaactaa
     8281 gagtgagaca gctgttctca ctcttttatt ttaaatatat tattaaaaag ctggtttatt
     8341 tttattaaat atattttatt taagattata taaactggtc atttacaatt gaataggagg
     8401 aactttaatg aaaaaaaatt tagaagctac aattgaggag attgtaacta aaataacgga
     8461 tgaacatgga tttgaaatgg ttgatgttga atatgtaaaa gaagcaggag aatactactt
     8521 aagagtatac atagataaag aagaaggaat atctttaaat gaatgtgaat tagttagtag
     8581 agaattaagt ccaatactag atgaaaaaga ccctataaaa gaaaattatt ttttagaggt
     8641 atcttctcca gggcttgata gagcattaaa aaaagacaga gattttgtta gatatcaagg
     8701 tagagatgta gatttaaaat tatataaacc attaaatgga tgtaagcaat ttgaaggtga
     8761 acttgtagga ttaacagaag ataataatat aaaaatcatt gcaaatggta aggaaatgga
     8821 atttaataga aaagatgttg ctattgtcag attagcaata aagttttagt ggtatattaa
     8881 atagggagga tataaaaaat gaatcatgaa tttatggaag cattagatga attagtagtt
     8941 gacagaggta tagataaaga aatacttata gatactatag aacaagctct tttaactgca
     9001 tacaagaaaa actttggttc agcacaaaat gttagagttg aatttgatag agacaaggga
     9061 gatataaaag tattttctca aagagttgtt gttgatgaat cagatttata tgatactttc
     9121 ttagaaatag agttagcaga tgctagagag ataaatccta attatgaatt aggtgatatt
     9181 atagaacatg aagttacacc taaaaacttt ggaagaattg cagctcaaac agcaaagcaa
     9241 gtagttgttc aaagaataag ggaagctgag agagaaatag tgtataatga atttatagaa
     9301 aaagaaaatg aaatagttac aggagaggtt gctagagcaa ataaaaatgt tgtttatgta
     9361 aatcttggaa gaatagaagg tataatgact caaagtgaac aaataccatt tgagaattat
     9421 aaagcaggtc aaaaaataaa attctatata cttgaagtta aaaagactaa caaaggacct
     9481 caaatagttg tatcaagaag tcatccgggt ctagtaaaga gattgtttga agaagaagtt
     9541 cctgaaatat atgaaggaat agttcaaata aaatctgtag caagagaagc agggtcaaga
     9601 actaaaatgg cagtaagatc tatagatgaa aaaatagacc caattggagc ttgtgttgga
     9661 ccaaaaggac ttagagtaaa aaatatagtg gatgaacttg gcgatgagaa aatagatata
     9721 ataaaatata gtgaagaccc agcagagttt atatcagcag cacttagccc atcaaaggtt
     9781 gttagagtag atatagatga agatgaaaag tctgccttag taatcgttcc agattatcag
     9841 ttatcgcttg ctataggtaa agaaggtcaa aatgcaagac tagcagcaaa attgactaac
     9901 tggaaaatag atattaagag cgaatctcaa gcagaacaag aaatgttaaa tcttgaaaat
     9961 tccaaagaaa tagaagctga ggatgttgaa gctgaattta tcgaccaaga agagttagat
    10021 acttcagagg ataattttag tgaagaagag taaggaggga tgattttgaa aaaagtaaaa
    10081 aaagtgcctc aaagaaaatg catagcatgt caagatagag actctaaaaa agagcttata
    10141 agaatagtta aaaataaaga aggaaaaata tttttagacc caacaggaag agccaatgga
    10201 agaggagcat atgtatgtaa aagctctgaa tgtctaaaaa aagctataaa gagtaaagca
    10261 ttaaataaag cttttaaaat agatgttcct gatgaagtct atgataatct acttatggag
    10321 ttagaagaat atgaaaaata ataaagaaaa agtactttcg ttcttagggc tcgcaactcg
    10381 tgcagggaaa atagtgtctg gtgatgattc aactttgctt gaccttaaaa aaggaaaagt
    10441 aaatttgatt ttaatcgcag aagatgcatc aaataatact aaaaaacttt ttaaagataa
    10501 atcaactttt agaaatattc catatctatt tttttcaaca aaagaggaaa taggatttgc
    10561 aataggaaaa tctccaagag cagttgtagg aataaaagat gaaaattttt ctaaaaagat
    10621 aattgaacta atagaaattt aaaataaaat agggggtgat cttgtgtcaa aaacaagagt
    10681 ataccaaata gcagaagaat taaatatatc aaatgaagag cttataaata agttagctga
    10741 attagatata aatgtaactg acaaagattc agtattagaa ggtgaagagt tagaattagc
    10801 acttgaaatg ttaggtgaag atttatctca agaaaatgga aatgttatag aaatagatgg
    10861 aaagttgaca gtacaagtat tagcaacgaa attagataaa tctccatcag aaataattat
    10921 gaagcttatg aaaatgggaa ctatggcaac aataaatcaa gagataagtt ttgagattgc
    10981 tgctttggct gccaaagact atggatttga attaacagta gctgaaagtg atgatacaga
    11041 agctttagaa atagaagctt taatggaaat tgaagaagac aaagaagagg atttaaaacc
    11101 tagaccacca gttgttacag ttatgggaca tgttgaccat ggtaagacat ctttactaga
    11161 tgcaataaga aaaactgatg tgatctcagg tgaagctgga ggaataactc agcatatagg
    11221 tgcttcagaa gttaaaatca atggacacaa aatagtattt ttagatactc caggacatga
    11281 ggctttcaca tcaatgagag caagaggagc acaagttaca gatatagcaa tattagtagt
    11341 tgcagcagat gatggtataa tgcctcaaac agttgaagct ataaaccatg ctaaagcagc
    11401 aggtgtacct ttaatagttg ctattaataa aatagataaa ccaggtgcaa acccagataa
    11461 ggttaaacag gaattagcag accaaggatt attagttgaa gactggggtg gagaagtaat
    11521 agcagttcca gtatcagcta agaaaaaaga aggaatagat acacttttag aaatggtatt
    11581 attggttgct gaaatggaag agttaagagc taatccaaat aaaagagcag taggaactgt
    11641 tatagaagct gagcttgata aaggaagagg gccagttgca acagtacttg ttcaaggtgg
    11701 tactttaaca gtaggtgacc caatcgttgc aggtgttgca tgtggtaaag ttagagcaat
    11761 gataaatgca aaaggtaaga gagtaaaaac agcaggacca tctacagcag tcgagatatt
    11821 aggtctatca gaagttccac aaggaggaga ccaatttgtc gaagttccaa ctgataagat
    11881 tgctagaagt gtagcagcaa gaagacaaca aatagttaga gatgaaatgt taaaatcaac
    11941 tcaaagatta tcactagatg ctctatttag tcaaatgagt gaaggttcta taaaagacct
    12001 taatatagtt ataaaagcag atgtacaagg ttcagtacag gcagttaaac aatctttaga
    12061 aaaattatca aatgaagaag ttcaagttaa agtaatacat ggtggtgttg gagctgtaac
    12121 agaatcagac atattacttg cagcagcttc taacgcaata ataataggat tcaatgtaag
    12181 accagttcca ggtgcagaat ctctaggaga aaaagaaaat gttgatataa gaacatatac
    12241 tataatatac aaggcaatag aagatataca agcggctatg actggtatgt tagaccctga
    12301 atatgttgat gaagaaacag gaaaagctga aataagagaa atatataaaa tatctggtgt
    12361 tggaacagta gctggatgtt atgtgactaa tggtaagata tttagaaatt gtaaagtaag
    12421 attagttaga gatagcataa taatacatga aggtgagctt gcagcactta agagatttaa
    12481 agatgatgta aaagaagtta attctggata cgaatgtggt atgagttttg taaattataa
    12541 cgacataaaa gaaggcgata tagtagaagc ttatataact aaagaagtag aaagaaaatt
    12601 ataaattcgt atcaaagaaa atcagttagt aaagaaggtc gatggtatgg catcatataa
    12661 tagaacaaga aggatagcag aagaaataag aaaagtcgta agtactatgc ttataaatgg
    12721 agtaaaagac cctagaataa catctatggt gagtgtaact gatgtagaag ttacaaatga
    12781 cctaagatat gcttatgtat atgtaagtat tctaggcgga gatgaagaat ccacactaac
    12841 aggtcttaaa agtgctggag gatatataag aagagaagta ggaaaaaata taaaacttag
    12901 atatattcct gagatagtat ttaaacttga tgattcaata gaaaaaggaa tgtatatgga
    12961 tagccttata aaaagagtta atgaaaaaaa tgctcaacaa aatgaggatg aaaattatga
    13021 tgaataatat ggatagtatt ataaactata tttatgaggg tgactatttt atagttacct
    13081 ctcatatcag tccagatgga gacaatattg gttctacact ttcaatgtat tatacattga
    13141 agaatttagg aaaaaatgta tattatgtac ttgatgatga agctccatta aatttaaggt
    13201 ttttggttga aggtgtaaaa atctataagt ctaatgaatt taatatgaag aactattctc
    13261 taattgcact tgattgtggg gataagatga gaatatgtgt gagtgatgaa atcaaaaata
    13321 atgcatcaaa attaatctgt attgaccatc atgctagtaa tgattcatat ggagatttaa
    13381 attatgtaga tattgatgca tcttctacat gtgaattagt ttataattta ttagttagat
    13441 ttcagcaaat aaaagatatt aatattataa atgaagatat agcaacatgt ttatatacag
    13501 gtcttgtaac tgatactgga aacttttcgt attcaaatgt acatgcaagt agctttgaaa
    13561 tggcaaaaaa tttacttgtt ttaggtgcac aaaaaaatac tataatacaa aatatatatc
    13621 aaagcaattc ttctggttat tacaaattat taggagaagc tctaaagggt ttggagatat
    13681 ttgattaaaa aatagttacg cacactcgtg actttagtca tgagttagta gctaaaatag
    13741 tcagcatata gggaaactta tatgtagaga taggataaaa cctatccaat actacttgaa
    13801 ttgctggaaa cccctaaagc taaccaaact aaaacataag gatgaaataa acctaagtgt
    13861 gaaagttacg aaagtagaaa aaattggtta gatggtataa ggttaaaccc taagtacttt
    13921 aaaatgggca atcagcaggt aaactccgaa taggagaaac ttcaacgact attcctcttg
    13981 agggaagtac actacaagct attggtagtg gaagtgggta gaccttaacg gataatgccg
    14041 aaggataaga tatagtctgt gcttacatga aagtgtaaga agttcataag agaactgcat
    14101 aggtagtagc gagcttatgt gaacgacaac ctcaaaaatg ataaaagtta agacttacgg
    14161 ttcttaaata tgttatttaa aattaaatat aaaaccttct aaataattgt tttaaataat
    14221 tacatttgtt aatattatga taggtggtta ataaattgtt caccacagca ttatataata
    14281 tattaaaatc attaaaaagt gtatcaaaaa acaattaaag tgaggtgata gcagtgaaaa
    14341 aagcttataa gtttagactg tatccaaata aaaagcaaca agagttaatt aacaaaactt
    14401 ttggatgttg tagatttgta tataataagt atcttgctaa aagaatagat gtttataaaa
    14461 ac
//
LOCUS       DAEPXW010000095        14418 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.097, whole genome shotgun sequence.
ACCESSION   DAEPXW010000095 DAEPXW010000000
VERSION     DAEPXW010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14418
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.097"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            146..688
                     /locus_tag="KRM55_002923"
     CDS             146..688
                     /locus_tag="KRM55_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1595139.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            1016..2509
                     /locus_tag="KRM55_002924"
     CDS             1016..2509
                     /locus_tag="KRM55_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1595140.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            2583..2816
                     /locus_tag="KRM55_002925"
     CDS             2583..2816
                     /locus_tag="KRM55_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595141.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            2972..3736
                     /locus_tag="KRM55_002926"
     CDS             2972..3736
                     /locus_tag="KRM55_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1595142.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIINFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            3757..3840
                     /locus_tag="KRM55_002927"
                     /pseudo
     CDS             3757..3840
                     /locus_tag="KRM55_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009005413.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(4021..7200)
                     /locus_tag="KRM55_002928"
     CDS             complement(4021..7200)
                     /locus_tag="KRM55_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1595143.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGINKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLDKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            7481..9658
                     /locus_tag="KRM55_002929"
     CDS             7481..9658
                     /locus_tag="KRM55_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1595144.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            9672..10094
                     /locus_tag="KRM55_002930"
     CDS             9672..10094
                     /locus_tag="KRM55_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1595145.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            10268..10843
                     /locus_tag="KRM55_002931"
     CDS             10268..10843
                     /locus_tag="KRM55_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1595146.1"
                     /translation="MVKVLAFMGSPRKKGNVDTILDEIIKGVNDNNVEVKKYYLNDMN
                     IKGCQGCLYCRKVPTCAFKDDMIDIYEDIKSAEYIIIGSPVYICQVSAQTKLLLDRLY
                     PLTEINKSKHTPRFGQKKLIMVYTQAAPISFLFKKYFKYTAKHLKGMGLNHYKTIVVT
                     KAFERNSTKKNFKVLKKAYKLGMKIAIDING"
     gene            complement(10968..11684)
                     /locus_tag="KRM55_002932"
     CDS             complement(10968..11684)
                     /locus_tag="KRM55_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1595147.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFQNKLDI"
     gene            11849..12574
                     /locus_tag="KRM55_002933"
     CDS             11849..12574
                     /locus_tag="KRM55_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1595148.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAIKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            12634..14226
                     /gene="hcp"
                     /locus_tag="KRM55_002934"
                     /gene_synonym="priS"
     CDS             12634..14226
                     /gene="hcp"
                     /locus_tag="KRM55_002934"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBH1595149.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTSNLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
BASE COUNT         5548 a         1615 c         2317 g         4938 t
ORIGIN      
        1 atgataaaat aagacaaata tgttaaaaaa atgataatca cggagaactt ttaccttctt
       61 caattaatat attattatta gtaataactt taaaattata ttactattat ataaaaattg
      121 gcttaaaaga aggtgaaaaa agtaaatgaa aatatgcata acagtaggtc atagtatact
      181 aaaaggtggt aaaagtacag gtgtaaatgg tatagttgat gaatacaatt ataataaaaa
      241 attagctcct atgttagctg agatgcttat aagtcaaggt aatacagtag atgtaataat
      301 ttgtccagaa aggcacttta tgtcagaaag agaagaattt ttctatagag ttccaaaagt
      361 aaacagtggt aaatacgatt tattagtaga gctacattta aataaagctg atggaacaca
      421 atgtggtaca gaagtgcttt actatggcac tgaaggatta gaatatgcta aaagagtatc
      481 taatagactt ggagaattat ttgaaaatag aggagctaaa aaaagagaaa atttatatat
      541 attgagaaat acaaatccag ttgcaataca gattgaaagt tttttctgtg ataatgtgaa
      601 tgattgtaac aaagcaaatg aatcaggtta tgattatata gcacgattga ttacagaagg
      661 tatattgaat aaagatataa atatgtgaga ttatggtgat ttaggtattg attaatacct
      721 tttaatatta gatataaata aaaatacaat gtattagtat aatttaaact ttcaaaagat
      781 agattagttt gattattgac aagagatacc tccttgaaaa tattgattta tcagtatatt
      841 taaggaggta tttaaatata aaaatttaat taatttgcta ctaaactata ggtttataga
      901 gtatatactt ttatcttcag tctaataaat aatataaaaa tagtagaacc ttgtattata
      961 ataatataat gtagaaaaat atatagataa gataaatata ataaggtggt aatatatgaa
     1021 atatacattt gaaaaattta agttaaatga aaagatactt aagtcattga agagtttagg
     1081 atataatata ccttctagag tacaaagaga agttattcca aaattattaa aaggtcaaaa
     1141 cttagtagtt aggtcaaaaa caggaagtgg aaagacagca agttttgcaa tacctttatg
     1201 cgagaatata aatgtagatt acaataatat tcaagctctt atagtggttc caacaagaga
     1261 attagccttg caagtaaaag atgagatatc agatataggg agactaaaga aggtgagatg
     1321 tagtgctata tttggcaaac aatctataaa agaccaaata gctgaattga aacaaagggt
     1381 tcatattgtt gtagctactc caggcagaat acttgaccat ataaatagag gttctattaa
     1441 gttggaaaat gtaaagtatt tagtaataga tgaggcagat aaaatgttta ataaaggttt
     1501 tgttgaacaa atggaaaaaa tattattaaa tttacctaag gagaaaatag taagtctttt
     1561 ttcagctaca atagatgaag agataaaata tatatgtgaa aaatatatgc tagattacag
     1621 tgttataaat atagaagaaa atgagagcga tactaatcaa aaaacaagac aaatagatga
     1681 caaaataatc aaggcaaatg gaagagagaa gtacatcctt ttaaaagaat taatatacag
     1741 cgaaaatcca aagagtgtga taatattttg taataccaaa gagaaagtat ctaaattata
     1801 taacaagatg agtaaagagg gttttttaat aagagagtta catgcagatt tatcacaaga
     1861 aagaagaatt tttgtaatta aggattttaa aaaccaaaaa tttaatatat tagttagtag
     1921 tgatgtagcg tccagaggaa tacatattga tgatatttct ttagtaataa attatgatgt
     1981 gccacaagat aaagaaaact atatacatag aataggtaga actgggagaa aaggaaatag
     2041 tggaaaggca attactatag taactgaaaa ggatgaaaaa tatatagaga atatagaaac
     2101 gtatatagga tataaaataa atgaattaaa agatatagaa aaaagtagaa ttacacatgg
     2161 caaagttttg tttgaagaat attcaaaagg aatcctaaaa aaagtatcaa agagaaaaaa
     2221 agttgataaa aattcttaca aaagtaaaga tataaaacta aatatagaaa gtgaagttgt
     2281 taaattatat ttaaatgctg gtaagaagaa gaaaataaga gttttagata tagttggtgc
     2341 atttagtaat ataaaaggta taactaatga tgatataggt gtaattgaag ttcaagattt
     2401 atgttcatat gtagatatat taaattataa gggagatttg atattaaaaa aatataagga
     2461 gatacctata aagaaaaaaa tggttaaagt gaaaagagat atacgataat ttagtcaata
     2521 ttgatgaatt gctttgttat cgaaatgaag ttgcaaaaaa cacaatagaa gttgttaagg
     2581 atttgaaagc tgaagatatg aaacgaaagg tctctccaat tgacttagaa aggattttgg
     2641 tgactggagg agtaataaag catgaagatt ctatttggtt gttggacttt tgggggaata
     2701 aagatattgc tggaattttg cttatgcctc ctactcgtca tgttatactt catttgaatg
     2761 attgttgtaa atggaaggaa tattttcgta caaaaaagaa attttacaga agttaaatta
     2821 taataaatta gacaaacaat agataaatta gcaaggaatg ttgattttat ctacattcta
     2881 agttatacta tttttaagtg gctaagggaa tagtcatttt aaatataagt aataaatata
     2941 tacctatagg gatattaaag gggggaaata tatggcatat tttaactata acgacaaaca
     3001 gtgctactat aatgaaattg gggatggtac accattactt tttttacatg gaaatacagc
     3061 ctcttccaag atgtttaatg atataatcaa tttttataaa gatgaatata aagtaatatt
     3121 aattgatttt gtaggtcatg gaaaatctca aatggtcgat aaattttctg ctgacttatg
     3181 gtttgatgag gctatgcaag tgatatgttt tttagaagca atgaactata aaaaagtaaa
     3241 cataattggt agtagtggag gagctcttgt tgcattaaat gttgcacttg agagacctga
     3301 tttagtgaat aaggtaattg cagatagttt tgaaggagaa gttcctctag agtcatttgt
     3361 acaaaatgtg aaaatagagc gtgaagcatc taagcaagat gatggtgcaa aagcttttta
     3421 tatttataat caaggagaaa actgggaaaa agttgtagat aatgatacag aagctatttt
     3481 tgaacattat aaaactatag gaaagttttt tcataagcct ctagaaacta tgcaaccaga
     3541 ggtgctttta acaggaagta gagaagatga gtttgtatct ctaatatcta gtgatttttt
     3601 tgaaaatact ttttcattac ttcttgaaaa gattaaaaat ggtaaaatgt atttgtttga
     3661 taaaggtggt catcctgcaa ttttatcgaa tggattagat ttttcaaatg tagcaaagaa
     3721 atttttagag gaataattta accaaaattt acaataatga aaactgtaaa atggattgca
     3781 aaacttacaa aagtgagtgt acatatactt cattattatg atgaaatagg attgttaaaa
     3841 caaaatattc taatagtcaa gttattacat ttgtatatgc aatatgtata gaaagagata
     3901 tcattagatt gtaaagttgg gattaaataa caatattaaa ttttatttat tcagatattt
     3961 tagcttaact atataaatgt tagaacaaat ttatatagtt aagctgtagg attaaataat
     4021 ttagttaaat aagtttatta tctcctcatc agatagactt tttaatacac cttcattaga
     4081 aagttctcca tttataaatt gatttataag ctctttttta ctttcttgta attttattat
     4141 tttttcttct atagtccctt tagcaatcaa ttttataact tgtactgaat ttttttgacc
     4201 aaatctatga gctctatcac tagcttgatt ttctactgat ggattccacc atgggtcaaa
     4261 gtgaattacc atgtcagcag atgtaagatt taaaccagtt ccgcctgctt ttaaagatat
     4321 taaaaaaact tttttatcca tactattatt gaactcatct acaagttcaa gtctttcttt
     4381 ggcattagtt ttaccatcta tataatggta tttaatttta tacttatcaa gttccttact
     4441 tatgttctta agcacagaag taaattgtga aaacaataat attttgtggt tttcgtttat
     4501 actatcccta agtatttcta aacatgtttc aatttttgaa ctttttttat tgtaatcttt
     4561 tactactata cttgggtcta aacaaagttg tcttagttta gttaaataag agaatataac
     4621 tattttatct ttctttagat ttttatcttt cattttatct tgtatatctt ttgaatatac
     4681 actatatatc tttttctgct ctttattcaa ttcaacaaaa aagttttttt caatcttatc
     4741 tggaagttct ttcataactt gttttttact tcttctaaga ataaaaggtt ttatcaattt
     4801 tttcaggttt ttaacattat cttctttatt tataaacaat tcctgaaact ttgctttact
     4861 atatagatag ccaggcatta taaaatcaaa tatagaccat aattctagta gattattttc
     4921 cataggtgta ccagtgagtg caaatttatt ttctgcattt atacttttta cagactcagt
     4981 tactaaagcc actggatttt ttatattttg agcttcgtct aatatacaat aatcaaactt
     5041 tatttcacta tatttgtcta aatcatttct aagagtacca tatgttgtaa gtattacatc
     5101 aaaattttct aattccataa aacatttttc tctatctctt ttatttccat gtatcaataa
     5161 aacttttata tctggagcaa acttttcaaa ttcatttttc caattataaa tgagtgatgt
     5221 cggtgtaaca ataagacttt ttttattaga taatgataat aaaaatgcaa tagtctgtat
     5281 tgttttacca agacccattt catcagctaa tataccacca aatttataat aatctaaaac
     5341 tttaaaccaa ttgaggccat ttatttgata gtcacgaagg tttgcattta aatttgcggg
     5401 aatttctaaa tttatgctat caaaatttct aaatttttca catatactgt ctagttcttt
     5461 tttaccatct ataaacttta aatttttact acgtattaca tcatttatat atagagcttt
     5521 atttttatga attttattat tttttgattt atccattata tctagatttt caactaattc
     5581 aaaaaaatct tttgtttctc tttctgataa atctataaag tttccatctt taagtttata
     5641 aaaagtacgt ttttcttgaa aagctttcaa aatatccttg tactcttttg gatttatatc
     5701 agatatatta aaattaaatt ctaggtaatt ctggttagtc tgattgattg aagcttgaat
     5761 tgatgaagcg ttatatattt ttttcaattt aaacttctca gaataatata tatctccaaa
     5821 ttcctttaga gattctaatt gtaaatctaa aaatgtaaat aggtcatggt cagttccttt
     5881 aaacacataa tgattatttt cctttgtaaa ttgtgaagaa gtaagtttat tttcaatagt
     5941 agcttccttt tgtatgttgg ggagcacaaa ttttttatct tcatcatcat atatatactt
     6001 tacatcacaa catatgttgc catcaatcat atcaaagtag aactcagatt taaaatcttt
     6061 tgttatatta ttttttatgt tatcatctaa atgaacttct tgagatatag attttaatct
     6121 aggaactagc aatcctaaaa catccttaga atcctcttta tcaaatttta actctttagt
     6181 ctttgataat atttgatata tttttgaata atcatgagct tttttatgtg ataataaata
     6241 gatattgcca tcatataaaa gtacatcatt ttttttagta agtggaacag gtagtgaatc
     6301 tttagaatat aagactattt tatcttctat atttttaaaa tcaaacctta caggtagagt
     6361 atcatttaat atctttggat gatattcctc tttagaaaaa ataagggtaa aatccttgta
     6421 cttaatagca tttaaaaatt gttttaaaga gcttgcattt atctccataa atttttttga
     6481 atgtgatgaa gaaaagttgt atgaaagatt tgtcccatat tcttctataa tatctactaa
     6541 cttctcatct tcatcagcaa aataatgagt gttggggttg taagtaaatt tcttcccaaa
     6601 atctaattca tatccattaa gttttgaata tgcaaattca gtaatgtttt ttaaaatgta
     6661 cattttatta attcctattt taaattcagc aattgcttta tttgaatcca catttatcaa
     6721 tacatctaaa ttaacccttt ctcttttagt attgtctaac aaagaaagta attgcttgct
     6781 taaatctaag ctggttttag aatttgtatt agaaagctta tccttatctg cacctaatat
     6841 atctattaga ataggaggaa catctttttt attttttatt tgttttaagc tttttatcac
     6901 aatagcaact atatgcttac atataaaaat acttttgccc tttgattgac agtcagcgca
     6961 actacaatca ttttcaatta tcttaaagtg ctttatatct atagttattg aattaaaata
     7021 aaagctataa ttatcttcag aattgactcc accacgaaat gtcaacaggt tattttgtag
     7081 gtcatcaata tctatgtcta tataatcaac taattgatta gtataatatt ttacacctct
     7141 tgaccatctt gatggttctg tatttcttct tattagttta tatatcatat ctattttcat
     7201 attattcacc ttacctcact gtatatatta taatctaaat gcattcaatt tacactctaa
     7261 atttaagact aaaattaagg cagatatgaa tagcttttat ctatcacaat atatgtgtaa
     7321 ataacaattt actattagat ttttattgaa ttatcttata aactatgaat gaaaaataat
     7381 tatataaata gattattaat aaatataaaa tcttattatt aaaaatattc ttagaaatta
     7441 cactgtataa aatataaagt atgatatttg aataaaaaga atgtataata agtataataa
     7501 tttgtattta ttattgggaa aggaaaatgt taatatggat agttatagac aacttaaagc
     7561 taaaataccc tgtaaggaaa caggtataga aataaagagg actttatgtg atatttgttc
     7621 tccaggagta cattgtggaa ttgatgcata tgttaaagat ggtaaagtaa taaaaataga
     7681 aggtacaaaa gaacatccaa tgaataaagg gttgttatgt accaaaggtc tttgcaatag
     7741 agaatatatc tatagagaag atagaataaa aacacctcta aaaagaattg gaaaaagagg
     7801 tgaaggaaaa tttaaaccaa tatcatggga tgaagcttat agagaaatag cagaaaaatt
     7861 aaatagagta aaatctgagt atggagcaaa gcatgtagct ttttttacgg gttatggaaa
     7921 gtggtataga ccttttttac aaaggtttgc atcttcattt ggttcaccta attatggtac
     7981 agaatctagt tcatgttcaa catcagcaca gatggctgga aatgttgcta ctggaagaaa
     8041 ctttacaatg caagatatgg agaatgcaaa aacttattta gggtggggat ttaatccata
     8101 ctactctaaa tttttaaata gtgtgaatct aataaaatta aaagaaaaag gtctaaaatt
     8161 tataattgta gaccctagaa taacaccgac aactcaaaaa ctagcagatt tacatttaag
     8221 aattaaacct ggaactgatg gagctttagc tcttggaatg gcgaatctat ttatacaaaa
     8281 ggatttaata gatagagaat acatagaaaa gcatgtacat ggatttaatg aatataaaga
     8341 atatgtaaaa ttatttgatt tagatactgt aagtagaatt acaggagttt ctaaagataa
     8401 tatagtaaaa gctgttgaga tgttgtcaca aggtccattt tgtataaatg aaagtgcagc
     8461 tccaatagtt catcatcaaa atggatttca aaactataga gcaatgatgt ctttatctgc
     8521 tataacaggt aattatgata gaataggtgg aaacatacca aaacaagatt actttgctgg
     8581 taagataggt ggattccaaa cactagaaaa agagtttgta aaagaagttc tacctaaaaa
     8641 tataaatgaa agaattggtg gagaaagatt tcctctatgg aatgaaatgg tgactcaatt
     8701 tcaagctatg gatttaccta ggcaaataga agaaaagaca ccatatgaaa taagagcttt
     8761 gttttgtcat gggataaatg ctagaatgtt tcctaattca gggagacttt ttaaagcgtt
     8821 gaatagtgta gatttttttg tgaatataga tttatttatg acagatacat caaaatatgc
     8881 agatatactt ttacctgcat gtacatcatt tgagagagaa gaatgtaaga gttatccagg
     8941 agggtatatt acatatacca aaaaagttat tgataaatta tacgattcaa aatcagatgt
     9001 agaaatactt tcagatttag caaatgctat gaatatagat gatgatttat taaaagcagg
     9061 ttatgaagca agtataagac atatgtttaa aaatacatgt gtagatgtag ataaacttaa
     9121 agaaagtgat ttaccattaa aatgtaaaga ttttaagcca tatatagtag gttcatatac
     9181 aagagaaggg tatgatacta gcacttctag gtttgaatta aaatctacaa ttattgaaaa
     9241 atataaagat tttgggctgg atgcactacc aacatataga ggatttaatg ataatataga
     9301 tgatgaatat actcatttat tgacatcagg agcaagaatt tcaaatgcac tacattcaag
     9361 acttcatgac atcaaacttt caagaatatt aaaaaatgaa gctagttgtg atatttctag
     9421 cttagatgca aaagaattgg gtgttatcag tggagattat ataaaaataa ctactaagat
     9481 aggaagtttg gatgtaaaag tcaatgttac tgatagagtc ttatataaga atatacatat
     9541 gtatcatgga tatagagaag ctgatataaa tagtattatt tgtgataatt ttgaccctta
     9601 tagtggattc cctgcgtata gaagttgtaa gtgtaagatt gaaaaaatga atagataaat
     9661 ggagagatat aatgaaaagt ttatttaaat ttaataaaga attatgtaca gcatgtggag
     9721 catgtttgct tgcatgtata gaccaaaatg ataataatat agacaatggt gaacttttta
     9781 gacatgtatt tacaatagag gaaggtgaaa atatagaata tttttcatta gcatgtatac
     9841 attgtaatga gccaaaatgt ttaggtgtat gtcctaaaaa ttgttttaaa aaagaagaag
     9901 gattcattgt attagacaat caaaactgta tagggtgtaa actttgtgaa aaagcttgtg
     9961 aatatggagc cttaatttat ggaaatgatg gtaaggcaaa taagtgtaat ggttgtattg
    10021 agagatataa gtgtggtatg gattcacctt gtgtaatggt atgccctaca ggagcattaa
    10081 aatttaataa ataattgtat taaattgcta tactactttt aaataattgt gttaagaatt
    10141 attttttgct atacttttgt aatataaaat gtaaataaaa caaatacaaa gtatataaaa
    10201 tatattttta gaataaagtg tgctttagat taaatttaga aaaataaatt agacaggaga
    10261 acttaatatg gtaaaagtat tagcctttat gggcagtcca agaaaaaaag ggaatgtaga
    10321 cacaatactt gatgagataa taaaaggtgt aaatgataat aatgttgaag ttaaaaaata
    10381 ttatctaaat gatatgaata ttaaaggatg tcaaggctgt ctatactgta gaaaagttcc
    10441 tacttgtgca tttaaagacg atatgattga catatatgaa gatataaaaa gtgctgaata
    10501 tataataatt ggttcgccag tatatatatg tcaggtatca gctcaaacaa agctactttt
    10561 agatagattg tatcctttaa cagagataaa taagtctaaa catacaccta ggtttggtca
    10621 aaaaaagtta atcatggtct atactcaagc agctcctatt tcgtttttat ttaaaaaata
    10681 ttttaagtat actgcaaaac atttaaaggg catgggatta aatcactaca aaactatagt
    10741 tgtaaccaaa gcatttgaaa gaaattccac taaaaaaaat tttaaggtat tgaaaaaagc
    10801 ctataaactt ggaatgaaaa tagccattga tatcaatgga tagataaaag tttaatttat
    10861 agtatagcta aaggagcatt aattattaat actccttttt tgtataaagg tttctagaaa
    10921 ataactaata aaaaacaata ttatttgaat acagatatta tacaagccta gatatctaac
    10981 ttgttttgaa aataaaagat ttcaaattta tttttgttaa aagataacaa gccttcatct
    11041 cgcatcttgc caagctctct tgacatagaa cttctgtcaa cacataaaaa atcagccatt
    11101 tcatttcttg aaaagggaat tgtaaactgg tggctacctg tttgttctat ctgttttgaa
    11161 aaatacataa gcaatttctc gcgagttgtt ttacgagaaa gtaattctat tttattgtga
    11221 agtaaaatgt ttttttcagc tattaattgt agcatatttt caacaagcct attatgaaat
    11281 acacatgcag atgaacaaat accagttaca cttttaaact ttataaataa aacttcgcaa
    11341 gaagatgttg tggttactgt aacattactt ttatgtagtc tagtacatgc gaatacctct
    11401 ccaaataaat ctccaggcaa gagttcagct acaatattcc tattcccttc gatatcttcc
    11461 tttattatat gagcacttcc tttaagcata attccaatag aagtaacttc acttccaaca
    11521 gagaatatta tactatcttt tgggtaagtc ttatctacaa cacctaaaca ttccaacatt
    11581 tcttcaagtt catcactttt aattccttca aatagaggaa tttttttaag taggtctata
    11641 tgcttttcta aaaatttttt caaataatca cttccttgtt gcatatgcaa ccgataattt
    11701 gttttcattg tactatacta agtttataaa agcaagggga tataaaaatc ctactacaag
    11761 aaatttgaaa taaagaaata taggtattaa aaataaatat ataagaaatc aatactttaa
    11821 attaaaaaaa ttttatgagg tgatataaat gatgagaaaa ataattaaaa ttgatgagga
    11881 aaagtgtaat ggttgtggac tatgtgttga agcttgtcat gaagaagcta taggaatggt
    11941 aaatggaaaa gcaaaacttt taagagatga ctattgtgat gggctgggag attgtctgcc
    12001 aacttgtcca acaaatgcga tttcatttga gtatagagaa gcagcagaat atgatgaagc
    12061 tgcagtaaaa gcaaatatgg aagcaaagaa agcacaaaag aaaactttag catgtggatg
    12121 tccaggttct cagtctaagt caataaatag agaggtttca aatagtacgt ctataagcaa
    12181 tgatatagta gagataaaag gttctcaact taatcaatgg ccagtacaaa taaaattagt
    12241 accaactaat gcatcatatt taaagaatgc aagtctttta atagcagcag actgtacagc
    12301 gtatgcatat ggaaattttc ataataaatt tatgaaaaat aaggttacat taatcggatg
    12361 ccctaaactt gatgaagttg actatgctga aaaacttaca gagattttaa aagaaaatga
    12421 tattaaaaat atagtagtaa cacgtatgga agttccttgc tgtggtggta tagtaaatgc
    12481 tattaagaca gctctacaaa atagtggaaa aatgatacca tggcaaatag ttactatatc
    12541 tgtagatgga aaaattgtag atggagaaat ttaattaagt gaattataga aaaatataat
    12601 aaattttaat aaataaaaag ggaggaataa aaaatggaaa aaatgttttg ttttcaatgt
    12661 gaacaaacag caggaggtaa aggttgtact ataaatggtg tctgtggtaa aaaggggggt
    12721 acatctaact tacaagacga acttacagga gtgttgattg gtctttcaag agcaactatt
    12781 ggaaataaga atagaccaac aagtgaaaca gataaaatta tgatagaggg gctattcact
    12841 actataacga atgtaagttt tgatgatgaa gctataaaaa gacaaattga aaaaactgag
    12901 gtagaaaaaa gtaaacttgt acctagatgt tcagattgtt caacaacttg taatagaaat
    12961 gataactatg atatgaagga tttatggaat gataatgagg acatacgttc attaaaatca
    13021 ttaatcttat ttggattaag aggtatggct gcctatgcat atcatgcaat ggtacttggt
    13081 tatacagaca aagacgtaaa tgaatttttc tatgaaggat taatagcagt tggaggagac
    13141 ttgtctattg acgaactttt aggtctagtt atgaaaactg gagaaataaa cttaaaatgt
    13201 atggaattgc ttgatagagc aaatactgaa acttatggaa caccagaacc aactcaggta
    13261 tctatgaaaa tcgagaaagg accatttatt gtagttacag gacatgacct ttatgattta
    13321 cacaaattat tagaacaaac gaaagataag ggtataaata tatatactca tggtgagtta
    13381 ttaccagcac atgcatatcc aaaactaaaa gaatataaac atctaaaagg taattttggt
    13441 acagcatggc aaaaccagca aaaagaattt gataatattc ctgctccaat attatttaca
    13501 acaaactgtt taatgcctgt taaagatagt tatagagata gagtatttac tacagaagta
    13561 gttgcttatc caggtatggt tcatattgat gaagataaag atttttctag tgtaatagaa
    13621 aaagctcttg aacttggagg gtatagagaa gatgttcata tgactggtat taatggagga
    13681 gatacattaa ctactggttt tgcaagaggt acagtttcat ctgtacaaga taaagtagta
    13741 gatgctgtaa agagtggagc tataagacac tttttattgg ttggaggttg tgatggtgca
    13801 aaacctggaa gaaattatta cactgaattt gtaaaacaag ctcctaaaga cactgttata
    13861 ttgacacttg catgtggaaa atatagattt aatgatttag accttgggga tataggtggc
    13921 ttacctcgtt taatggatat gggacaatgt aatgatgctt atagtgcaat taaagtggca
    13981 gtttcattgg caaatgcttt tgaatgtgga gtaaatgatt tgcctcttag catggtactg
    14041 tcatggtatg agcagaaagc tgtttgtata cttcttacac tacttcattt aggtatcaaa
    14101 aatatctata tagggccttc tttaccagca ttcttatcta agaatgtatt agatatattg
    14161 gttgataaat ttgcattgac acctatatct actcctgaag aagatatgaa gaagatttta
    14221 ggataaataa atatatctat acttaaagat atttatagtt aaaatatttt taagtatgcc
    14281 acaattaaga taaggggtta aacttaaaat ttgattaaaa aatcaatttt gagacgaccc
    14341 tttatttatt ttttgtaata attgaaaaat aaacctgctt tcagtatatt ctttttaaga
    14401 atctttgtat taaattta
//
LOCUS       DAEPXW010000096        13670 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.098, whole genome shotgun sequence.
ACCESSION   DAEPXW010000096 DAEPXW010000000
VERSION     DAEPXW010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13670
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.098"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            162..1475
                     /locus_tag="KRM55_002935"
     CDS             162..1475
                     /locus_tag="KRM55_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1595150.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            1647..2822
                     /locus_tag="KRM55_002936"
     CDS             1647..2822
                     /locus_tag="KRM55_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBH1595151.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            2925..3944
                     /gene="hrcA"
                     /locus_tag="KRM55_002937"
     CDS             2925..3944
                     /gene="hrcA"
                     /locus_tag="KRM55_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBH1595152.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            3974..4594
                     /gene="grpE"
                     /locus_tag="KRM55_002938"
     CDS             3974..4594
                     /gene="grpE"
                     /locus_tag="KRM55_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBH1595153.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            4686..6533
                     /gene="dnaK"
                     /locus_tag="KRM55_002939"
     CDS             4686..6533
                     /gene="dnaK"
                     /locus_tag="KRM55_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBH1595154.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            6744..7898
                     /gene="dnaJ"
                     /locus_tag="KRM55_002940"
     CDS             6744..7898
                     /gene="dnaJ"
                     /locus_tag="KRM55_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBH1595155.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            8864..9799
                     /locus_tag="KRM55_002941"
     CDS             8864..9799
                     /locus_tag="KRM55_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH1595156.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EGLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            9835..11208
                     /locus_tag="KRM55_002942"
     CDS             9835..11208
                     /locus_tag="KRM55_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1595157.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(11396..12163)
                     /locus_tag="KRM55_002943"
     CDS             complement(11396..12163)
                     /locus_tag="KRM55_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595158.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEMLGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(12193..13302)
                     /gene="ugpC"
                     /locus_tag="KRM55_002944"
     CDS             complement(12193..13302)
                     /gene="ugpC"
                     /locus_tag="KRM55_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBH1595159.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
BASE COUNT         5259 a         1528 c         2388 g         4495 t
ORIGIN      
        1 ttttagagaa tattttagaa gttacgattg tatgattttt aaatgcatag gcatttactc
       61 taggactata gactaatata aaaaaaaact ttgggaatac taaaaccata aatttataaa
      121 attaatattt tatatactgt aaaacagtga ggagggacag tatgcatact caactacaaa
      181 agactattgg tctttcagca gctctttcta ctgttgtagg tatggttata ggttcgggag
      241 ttttttttaa gccacaagca atatacacta caactaatgg agctccaggt ctaggtatta
      301 tagcgtggct tttaggtggt tttataacaa taactgctgg gcttacagct acagaaattt
      361 cagctgctat accaaaaact ggtggtatga tgatttatat cgaagaaata tatggagaaa
      421 agttaggttt tttaactgga tggatgcaaa ctgtattatt tttcccaggt acatcagcgg
      481 cattaggagt aatatttgct caacaagcat ctgaactttt aggaatgagc ccaaataata
      541 tggcaaatgt acttcctata gcaattggag ttatactatt tttagcgtta ttaaatataa
      601 taggttcatc cttaggagga aaagttcaga cagtagccac tattggaaag atgatacctt
      661 taattttaat aatagtcttt ggatttatta aaggtcaaag tagtgaagta ttaaatccat
      721 ttgtaggaga tggtgtaaat gcatcaaatg cacttggaca agtattaata gctactttgt
      781 ttgcatatga tggttggata aatgttggag ctatatcagg agaaatgaag tctccagaga
      841 aagatttacc aagagcaata gttggtggtt tatcattagt tatggcagtt tatattataa
      901 taaatatagc ttatctttgg gtagtaccag caagtgaatt agcaacagtt acttccccag
      961 ctacattagt agcaacaaga ttgtttggaa atataggtgg aaaagtaata actgtgggta
     1021 tattaatatc agtatttggg acattgaatg gatatttatt aacaggttca aggatacctt
     1081 atacattagc tgaaatggga actttaccag catctaaaac tcttttaaaa gtaaattctg
     1141 gaggttctcc tgtaaattca atactactta taactgtgtt agcctgtgta tatgcattat
     1201 ctggtcaatt taatcttttg acagacttaa caatattttc aatatgggta ttttatgtat
     1261 tgacttttat aggtgttatg aggcttagaa gacaaaagcc agatttacac agaccatata
     1321 aagtcccttt atatccaata ataccaatta tagctatatt aggtggactg tttgtaataa
     1381 taaatcaaat attgacttca acagtcatat ctttaggcgg aatatttata acactattag
     1441 gtttaccagt ttattattat atgaaaaaaa gataactact taatttaagt tagataaatt
     1501 tgggtaaagg tgaaaattaa cttttatcca aattttttat actgttatac aatataagta
     1561 ttatatattg cttgatgtgc tattttgttt gatttataat ttagtaattg atgttttaag
     1621 ataatttaag aaatgaggag tgaaagatgc taggacttta tgtacatatt ccattttgtg
     1681 tgaaaaaatg taagtattgt gattttaatt cttataaaat ggacatagat tcaaaaaaaa
     1741 gatatataga agacttaaaa atagaaatgg aattatatag taataaatta tataaagata
     1801 ataaatataa aaataaagaa tgctgtagtc taaataaaaa tgacaaaata acgagtatat
     1861 ttgtaggggg aggtacacct agtatactaa cctctgatga aataagagaa gtatttataa
     1921 gtataaaaga aatgtttgat atagatgaga atgcagaaat aactatagag tgtaatcctg
     1981 ggacattaac attagaaaaa ttaaaaacta tgaaagagat tggcataaat agacttagta
     2041 tagggctaca agctattcaa gaaaagcatt tgaactttat aggaagaata catacttatg
     2101 aagaatttga gaaaaactat aaagatgcat taagtgtagg ttttaaaaat attaatatag
     2161 atttaatgta cagtcttcca aatcaaactc tatgtgattg gaaggaaact cttgaaaaag
     2221 ttgtacactt aaatccaaca catatatcag cttattccct tatactagaa gaaggaactg
     2281 aactatacaa tatgtatgaa agtaataaat ttgaacttat agatgaaaat gtagatatag
     2341 aaatgtatga gtatacaata aactacttaa agtcaaaagg atataatcaa tatgaaatat
     2401 ccaactactc aaaagaaggc tataattgtg agcataatat tttatattgg gaatgtgaac
     2461 attatatagg gattggagca ggagcttctg gctatattaa tgagaacaga tacaataatg
     2521 tagaatcttt agaagattat catttaagtt tggtaaaaag agaaaaacca atacaagaaa
     2581 atgaaattct ttctgagaaa gatatgatag aagaaaagat atttatgggg cttagaatga
     2641 ataaaggcat aaaatttgaa gattttaaaa aaaaatttgg aatagatttt agagagaagt
     2701 ataataagca aatagaaatg ctattagcta gaaagcttat aaatcagagc tttgaaggta
     2761 tacaattaac tcaaaaagga agagaaatat ctaatagtgt atttatagaa tttatggaat
     2821 aatttttaag gtgttgacaa aataaattta taatggtata taatatatat aatcttttta
     2881 gcactcgaac ttagtgagtg ctaacagcta ggaggtataa taatatggaa ttaaatgaaa
     2941 gaaaattaaa tatcctcaaa gctatagtta aagattatat agaaacagct gaagctatag
     3001 gttctagaac aatatctaaa agacatgatt taggtgttag tgctgctacc ataagaaatg
     3061 aaatggctga ccttgaagaa ttagggtatt taattcagcc tcatacttct gcgggtagag
     3121 ttccatctga aaaaggctat aagttatatg taaactctct tatgagtaaa agcgaattgg
     3181 atgataatga taagattctt attgaacaat gtatgaatca caatataaat catataaaag
     3241 aattgattca tgaaacttct aagctattat cgcaactaac aaactataca actgtagcag
     3301 ttactaagag tttaataaat caaagtgtta taaagcacat acagttggtt gctatgaatg
     3361 acaataatat tttacttata gttgtaacag ataaagggga cttaaaaaaa gctaacctta
     3421 caactaatgt atatttagat caatctaagt taaatttgat ttctgataat cttacaagga
     3481 agctcttagg taaaagtata acagatttgg atgataatct aattgctttt attaaatacg
     3541 aaataagtga gtattctggg cttatagatg agcttttaaa tgctttgaac tcaaatatga
     3601 aagaagaaga tttttctcta tcattaaatg gagctactaa catatttagt tatccagaat
     3661 ttaatgatgt attaaaagca aagtcatttt taaatatgtt ggaaaaaaag gaaacaatag
     3721 ctgacataat taaatcaaag ggaatacaaa aagacaatct aaatataata attggtagtg
     3781 ataatgattg tgaactggca caggattgta gtatagttac agcaacttat aatgtagata
     3841 gagacttggt tgggcgaata agctttatag gccctaccag aatggattat gctagaattt
     3901 actctataat aaattatatg agtttattaa ttaatagaaa gtaaagaaat tttaaattgc
     3961 gaggtgtaaa gtcttggata aaaaaaatga gcaacaggaa gtaagagaag aaaatgatac
     4021 ttctattaac caagaatcgg aaactcaagt agagttagaa gaggaagttg ttaatgaaga
     4081 atgtgaaaca tcaagtgaaa aaactgatga aaaagaagtt gatgatgaaa atgtaacaga
     4141 tataaattct aagttagcag aaaaaaaatt gcaggatgag ttggatgaat taaatgataa
     4201 atatcaaaga cttcaagccg aatatgcaaa ctacagaaga agaactcaac aagagaaaga
     4261 gacaataggc gtatttgcaa atgaaaaaat aataactgaa ttgataccag ttatagatag
     4321 tatggaaaga gccttagatg catgtgaaga taaggaagat actatgtata agggtataag
     4381 ccttgtacat aaacaattaa tagacacttt agtaaaattt ggagtagaag aaatagaagc
     4441 agaatctaag gaatttgacc ctaatctaca tctagcagtt atgcaagaaa gtgtagatgg
     4501 agttgaagca aatcaaatag taatggtact tcaaaaagga tataagctag gaactaaagt
     4561 tgtaagacct tcaatggtta aagtttcttg ctaagtataa attaaaggtt aaattattta
     4621 acctaatata aaatattaaa ataagtaaaa cttaattata taattactcg aggaggattt
     4681 tagtcatggg aaaaataata ggaatagatt taggaacaac aaattcatgt gttgcagtgt
     4741 tagaaggtgg agaagcacaa ataatagcaa atagtgaagg tatgagaact actccatcag
     4801 tagtagcatt tacaaaagat ggtgaaagaa tagttggaga acctgcaaaa agacaagcag
     4861 ttacaaatgc agataaaaca ataacttcta taaaaactca tatgggaact gattataaag
     4921 taaatataga tggaaaatca tatactccac aagaaatatc agcaataata ttacaaaaat
     4981 taaaatcaga tgcagaaagt tacttaggac aaacagtaac agaagcagtt ataacagtac
     5041 cagcttactt tacagatgct caaagacaag caactaaaga tgctggtaga atagcagggc
     5101 ttgatgttaa gagaataata aatgagccaa cagcagcagc tcttgcttat ggtatggata
     5161 aattagacca agaaaagaaa atattagtat ttgacttagg tggaggaact tttgacgtat
     5221 ctatacttga aataggagat ggaacttttg aagttttagc tacagctggt aacaatagat
     5281 taggtggaga tgactttgac caaatagtaa tagattattt agcagaggaa tttaaaaaag
     5341 ctgaaggtgt agatttaaga aatgataaaa tggctcttca aagattaaaa gaagcagcag
     5401 aaaaggctaa gaaagaatta tcatcaacaa tgagttcaaa cataaactta cctttcataa
     5461 ctgctacagc agaaggacca aaacacttaa atatagattt atcaagagct aaatttgaag
     5521 aattaactag aggtttagtt gaaaaaacta tggaaccaac taagacagct ttacaagatg
     5581 caggactttc tacaggtgat atagatgatg tattattagt aggtggttct acaagaatac
     5641 cagcagtaca agaagctgtt aagaagttta taggaaaaga acctcataaa ggtataaacc
     5701 cagatgagtg tgttgcagca ggtgcttcta tacaagctgg agttttagca ggggatgtta
     5761 aagacttatt attactagat gttactccat tatctcttgg tatagaaact atgggtaatg
     5821 taatgactaa gataatagaa agaaatacta caataccaac taagaagtct caaatattct
     5881 caactgctgc tgataaccaa acagctgttg atatacatgt tcttcaaggt gaaagaagta
     5941 tggcttatga caatacaact ttaggaagat tccaattaac agatatacca ccagcacaaa
     6001 gaggaatacc tcaaatagaa gttacttttg atatagatgc aaatggtata gttaatgttt
     6061 cagctaaaga tttaggtaca ggaaaagagc aaaaaataac tataacatca aacactaatt
     6121 tatcagaagc agaaatagag caaaagataa aagaagcaga aatgaatgca gaagctgaca
     6181 aacaaaagaa agaaaaaata gaagcattca atcaagctga atctactata tatcaaactg
     6241 aaaaaacttt aaatgaactt ggagataaaa taagttcagg tgaaaaagag gatatagaaa
     6301 aagctatagc agacttaaaa gctgtaaaag ataatcaaga tgctacagca gaagaactta
     6361 agaaagctac agatgaagta atgactaagt tccaaaaagt atctcaagaa atgtaccaaa
     6421 aagcagctca agaacaacaa gcggcacaag gtgcagaaca agcacaagac aatggaccta
     6481 aagatgacaa tgtagtagat gctgacttta aagaagtaga tgaagataaa taagctatat
     6541 aatatgtaac actaaatgat aattggaaca tatatgattt gtgaaaatca tatagatgtt
     6601 aaagatatat ggacaatata catcataaag aatataatat atcatagatt atataactta
     6661 aagtagaata taagaattaa tgatagcttg tagtttatta ttctacaagc tatcgttttg
     6721 taaaatgaag gtggtgtcaa tttttgagta caaaaaggga ttattatgaa gtcttaggta
     6781 tcagtaaagg tgcagaagct caagagataa aaaaagctta tagaaaatta gcaatgaagt
     6841 accatccaga tagaaatcct ggagataaag aggcggaaga aaaatttaaa gagataaatg
     6901 aagcttatga agttctatct gatgatacaa agagaaaaac ttatgaccag tttggacatg
     6961 atgggctaaa tggtcaaggc ggttttggtg gtcaaggagg atttggcggt caaggctttg
     7021 gtggttttga agatatgttc ggagatatat ttggtgacat gtttggagga agcttcggag
     7081 gtggaagagc aagaagaaga gggcctcaac gtggtgcaga tataagacag agtgttacta
     7141 tatcttttga agaagctgca tttggtaaaa agatgtctat aaaagtaaat agaagtgaag
     7201 aatgtgaaga atgtaatgga actggagcaa aaccaggaac atcaaagaaa acttgttcaa
     7261 cttgtaatgg aactggtcaa gttagaactg ttcaaagaac tccatttggt aatatagcaa
     7321 gttcaagacc atgtagtgct tgtaatggaa ctggagaagt gattgaatct ccatgtagta
     7381 aatgtcatgg aactggaaat acaagaaaag ttaagactat agaagtagat atacctgctg
     7441 gtatagatga tggtcaaatg ataaaacttt ctggtcaagg tgaagtagga gaaaaaggtg
     7501 ctccaagagg agacttatat attgtagtta atgttaagtc acatccacta tttactagag
     7561 atggaaatga tatttatttt gaaatgccaa ttacatttgt tcaagcaact ttaggtgatg
     7621 agatagaagt acctactttg gatggaaaag ttaaatatag tgtgccagag gggacacaaa
     7681 ctggaactgt atttagactt aaagagaaag gaatccctag aattagaggt aattcaagag
     7741 gagaccaata tgttaaggtt gtagttgaaa ttcctaaaaa attaaacgat aagcaaaaag
     7801 aactattgag agaatttgcg aaggagtgtg ggtcgaacgt ccacgaaaag aagaaaacct
     7861 tcggacaaaa gatagaagat atgtttaaga aaaagtagtt aaagtagcca atatataatc
     7921 atatttttaa aatcttagtt atttataaga ttgtcaaagg agatattatg atttttatat
     7981 tggctatttt tgtataaaaa ataaatgtgc ataaaataaa actgaatata aataattttc
     8041 tgaaaaatac ttgtcctaaa atatataata tgctataata taatcaaata aaagaaaggg
     8101 gtgattccag tgggaacgga tgtggcactg ccaaatgatg aagaaaactt tattgtaata
     8161 tacaaaataa aattagatac ttttagtgct agattaagta ctggaaaaac tcatgagctg
     8221 ggataattat tgtaattacc tagactcaaa cttttagtag taaaatagta atattatata
     8281 gacaaggtat ctaattttta aatcttttgt atgaattaaa atttttataa agggtatatc
     8341 tgattagaat gtaattaggg aaacctagtt gtgaattact tttagtatat acatgtgtaa
     8401 agaaatatgt atatggtatt gggtattgtg ctagatgtgt atgtaaagga atatgtgtct
     8461 agttgggtat atgtaaagaa atatacttat aatctatgaa aaatttttag tataaattgc
     8521 taaaacattg agattgtttt ttatagaaag ttagtttata ccaactaaaa atgtgcttaa
     8581 gatttgtttg atgtttaatt ataaataagg ttgtagataa aaaaataagt aaagacaaag
     8641 gtttaaaata cttgctttaa atatagtttg ttttgaacac ttgccaaatt aaaataatta
     8701 ataaaataga catcttctca tagtaaaata tactgtgaga ggatgttttt gctttgttca
     8761 taaactttta tgaaaaattt gcatagtgtc acattttaat atactatata tataataaaa
     8821 tatagataaa attaaatgat tcaaaagaga aaggtgaaaa gagatgtatt atataggtgt
     8881 agacatagga ggaacaggta tacaagcagg agtagttgat aactatggga agataatttt
     8941 taggtcagag tgtaaaacag taattgaaaa aggatttgaa ggaatactta atgacataaa
     9001 aataatgatt tataagttgt tggaagataa taaacttact atgagtgaca taaaatctat
     9061 tggatttggt gttccaggtt ttataaataa agaaggatta gtaacttgtg taaatttaaa
     9121 atggaataaa aaagctttta ataaagagtt aaaaagaaga tttccagatg ttgaaattca
     9181 tggagaaaat gatgcaacag tagcagcact tggagaagca aagtttggaa gtatgaaagg
     9241 tgctaatgtt ggagtattat atactttagg aactggtgta ggtggaggaa tagtaattaa
     9301 tcaaaaagtc ttttctggag cacatggatt gggttcagaa ataggtcatc aaattatagg
     9361 agaaaactat tttaattgta attgtggaaa taatggttgt gtagaaactt tttgttcagc
     9421 aactgcaatt ataaagtatt ctcaaaaact gatagaagaa ggagaaaaga gtaggatttt
     9481 agatttggca gagggaaatt tagaaaatgt aaatgcaaag atggtgtttg atgcatatag
     9541 agaaaatgat ttagtggcaa ttaaagtaat aaatagattt aaagagtatt tagcaaaaac
     9601 ttttgcaaac acaataaatt ctttagaccc agaaattata tctataggag gaggcatttc
     9661 taaatctagc gatataatac ttgatggaat agaaggtttg gtaagaaaat ttgtattata
     9721 caaaacagaa gatatagcta caattacatg tgcaacttta ggttcagacg caggaattat
     9781 aggagcagct tttttataat gtaaatgaac tgcttattgg aggcgtgatg atatatgggt
     9841 aaaacaaatg ctagaagaac gctttttttg atagcaatag gttcaggaac tatgctgaat
     9901 cctcttaatt cttctatgat ttcacttgct ttacatagta tacaaaatga ttttcatatt
     9961 agttttacaa ctgtatcttg gattgtttca gcattttacc tagctagtgc tattgcacaa
    10021 ccagtttcag gtaagatagg agatttaata ggtagaaagg tcttattttt gagtggtttg
    10081 atgcttgtaa ttttatcagc atccatagta ccacttgttc aatcattctt tatattgatt
    10141 tttataagag taattcaagc aattggaaca agtaccctat atccatctgg agttgctctt
    10201 atacaaaata atataaaaga aagacaatct tctgcattag cagttctaac catttttgct
    10261 tcaactacag caggattagg tccgacactt ggaggattat tgttggactt aggaggatgg
    10321 catgctatat ttcttgtaaa tatacctgtt gttttggttt ctatatgctt agggtatttt
    10381 ttattcccaa aagaagtaaa agaaaagaaa tctataaaag aaactttaaa aaatgttttg
    10441 tcaagattag atattattgg catacttcta ttttcaattg caatgatttt tatattacta
    10501 tttttgctat ctatgaagga atcttttaac ttagaacaac ttgtatttgg tataatactg
    10561 atgtgtcttt ttatttggca tgaattgaga acaaaattgc catttataga tattaagctt
    10621 tttgtaagta atcctaaatt gtcaaaagtt tacttgcaat ttattatatt aaatttcttt
    10681 aattatattt tgttttttgg tcttcctagt tattttcaag atgccttaca ttatagtgca
    10741 aagtcgactg gattatttat gctatttatg tctggtatag gtatatttat atctccatta
    10801 actggaaaat ggatagataa atctggaact agatttcctc ttgttacatc atcaatcttt
    10861 atgtttatta gtgcagtact tctttcagta gtttttatcc atatacctgt aataggaaag
    10921 ggtattatat tatcattagc aggtattagt tatggagttg gtaatgtagc cctgcaatcc
    10981 tctatgtttg aagaaagtcc tcgtgacagt atagggacag cttctggtct gtttcaaact
    11041 agtcgttatt taggttctat tttagcaact gttttacttg gaatggtatt tgaagtaaat
    11101 ataacatcag aacaatttca gatattaggt tatgttatgg tggtcttagg tacaataagt
    11161 tttttattaa attttatatt aaagaaagaa ttaagaaaag tagaatagtg gatttatgga
    11221 tttaataagt ctaataactg ataagtttaa aaatattgtt tgtaaaacat aactggtttg
    11281 atatttatta attctaagtt ttgaagcata gagtactcga taagtataca atattttgaa
    11341 ttaaaattaa gcagaaattt gaactagtct ttcaaatctc tgcttaattt agtagttaaa
    11401 tttttttata gagaaaataa gatttgacac ttagataaaa aatcattgca ttttcaaaat
    11461 tctttaaatc aaacccaagc atctcattaa tcttttccaa tctatatact agcgtgtttc
    11521 tatgtaaaaa catactagta gatgtcttag aaatatttaa atcattattt ataaatttta
    11581 ttcctgtata tagaagttct tcgtcaatag atttaatctt attaaaatct attaatttat
    11641 tgagtatatt atcctcatta attaaatcta aagttttata tctaataagg tcaaacaaat
    11701 ttaaaaactt attttcagcg ttgtctttta taatatgagg tagtaaatca gaacataact
    11761 gtaatctaaa atcaaaatca gctttactat ctaatttacc aagataaaaa atataagtac
    11821 tttgataagt ttcagtttca attatatttt gtgtagttac attaatatct aagttatatt
    11881 tagaatttac tataaaaaaa ccattgtgtt gtattatatt tatatcttca aataaattat
    11941 aaaaaatatt ttttagatat tcaaagtcta tatgagattg gtaaattaaa taaaagttgc
    12001 cttttaaatt atcaagatta tttttatcta gaaaatcaat aacataaata gcattattga
    12061 aagtaactaa atggctacta gcatctaact tttggttttc atatggatag atatttattt
    12121 ttttattaag ctgtctttct aaaaaatctt ttaactcttc cataaagtct ccttaaaaat
    12181 aagattatat tcttatctta tagctaaagt agtttctttg tcaaatatgt gtactctact
    12241 gttgtcaact gaaagtgtta agtcatcacc aacattaatt ctgtttttac tgtcaaatct
    12301 aattgttatc gtattttcgc ctagttttaa gtgagcataa gtttctgctc ccataagttc
    12361 ttttatttca attcttgatt taaaacaagt atctggatta gatttaataa aagtatcttc
    12421 tacatgaata tcttctggtc tgatacctat aacaacttca ttattaatat aattgtcttt
    12481 tattaaatca tagtgttttt ctttattcaa tttaagctta atatgttcat tttgtgcata
    12541 aatttcatca ttttcttcta ttaatattac atcaataaaa ttcatctgtg gtgctccaat
    12601 aaatcctgca acaaatatat tagctggata atcgtataca tcttgtggag ttgcaatctg
    12661 ctgaactact ccatccttca ttactacgat tctatcagcc atagtcatag cttcaacttg
    12721 gtcgtgtgtt acatagataa atgtagttcc aagctgttgg tgtagcttag ttatctctgt
    12781 tctcatagca gttctaagtt ttgcatctaa gttggataga ggttcatcca ttaagaatac
    12841 cttaggattt ctaactattg cacgtcctaa ggcaaccctt tgtctttgtc ctccagataa
    12901 tgttttaggt tttttattta aaagaggtag taagtctaat attttagcag cttctttaac
    12961 ttttttgtct atttcatctt taggcaattt tctaagttta agtgcaaatg ccatgttttc
    13021 gtaaacagat aagtggggat ataaagcata gttttgaaaa accatagcta tatctctatc
    13081 ttttggttct atatcattta caagtttatc tccaatgtat agttctcctt cagagatttc
    13141 ttcaagacca gcaatcattc taagtgtagt cgatttacca caaccagatg gtcctactaa
    13201 aacgataaat tctttatctt taatgtctat atttatattt tttactgcat taaatccatt
    13261 tgagtaaagt tttgatatat tttttaaaat tacttctgac ataatatcct ccttgatatt
    13321 taaattttaa ttatatagta tcaaattttt ttattatatt aaatgtgtaa aatggctaaa
    13381 tgtatttgtt taatatgtat attaaaaatt tagactaata gttttttaat ttaaaaaatg
    13441 tattttaatt tagaaaagtt ttatgtataa tagtatatag tttttagttc aacaacatgg
    13501 gatttaaatg tcaatttaat ttataaggaa atagtattat attaatagtt tagattaaca
    13561 atgaggagta taaaaataaa ataatataat taagattgta ttgattgtat ataattaaat
    13621 ttctagtaaa tttagttata tataattata tttatccggt caaattaatt
//
LOCUS       DAEPXW010000097        13619 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.099, whole genome shotgun sequence.
ACCESSION   DAEPXW010000097 DAEPXW010000000
VERSION     DAEPXW010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13619
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.099"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            194..1312
                     /locus_tag="KRM55_002945"
     CDS             194..1312
                     /locus_tag="KRM55_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1595160.1"
                     /translation="MIVVEKAYKFRIYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELNWLKEPDKFSLQNALKDLDNAYEKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTDVDIEVFENTNNQIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVAGLQEHIANQRKDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWYGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITTQNK"
     gene            1822..3228
                     /locus_tag="KRM55_002946"
     CDS             1822..3228
                     /locus_tag="KRM55_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1595161.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            3256..4104
                     /locus_tag="KRM55_002947"
     CDS             3256..4104
                     /locus_tag="KRM55_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1595162.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            4776..5468
                     /locus_tag="KRM55_002948"
     CDS             4776..5468
                     /locus_tag="KRM55_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595163.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            5465..6400
                     /locus_tag="KRM55_002949"
     CDS             5465..6400
                     /locus_tag="KRM55_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595164.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPYDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDRDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTIFTVSLPLI"
     gene            6548..7471
                     /locus_tag="KRM55_002950"
     CDS             6548..7471
                     /locus_tag="KRM55_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595165.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            7455..8225
                     /locus_tag="KRM55_002951"
     CDS             7455..8225
                     /locus_tag="KRM55_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595166.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVSKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTALPIVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTSACVGILCLITIIAVLLICMIYKKQEN"
     gene            8235..9017
                     /locus_tag="KRM55_002952"
     CDS             8235..9017
                     /locus_tag="KRM55_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595167.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQIVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVAKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            9395..9931
                     /locus_tag="KRM55_002953"
     CDS             9395..9931
                     /locus_tag="KRM55_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH1595168.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            9963..10352
                     /locus_tag="KRM55_002954"
     CDS             9963..10352
                     /locus_tag="KRM55_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH1595169.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            10389..10775
                     /locus_tag="KRM55_002955"
     CDS             10389..10775
                     /locus_tag="KRM55_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBH1595170.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            10902..12344
                     /locus_tag="KRM55_002956"
     CDS             10902..12344
                     /locus_tag="KRM55_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH1595171.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            12641..13456
                     /locus_tag="KRM55_002957"
     CDS             12641..13456
                     /locus_tag="KRM55_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1595172.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEHAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         5015 a         1654 c         2533 g         4417 t
ORIGIN      
        1 ataaaagtta agacttacgg ttcttaaata tgttatttaa aattaaatat aaaaccttct
       61 aaataattgt tttaaataat tacatttgtt aacattatta taggtgatta ataaattgtt
      121 caccacagca ttatataata tattaaatgt gataaaatca ttaaaaagtg tatcaaaaaa
      181 caattaaagt gaggtgatag tagtggaaaa agcttataag tttagaatat atccaaataa
      241 aaaacaacaa gagttaatta acaaaacttt tggatgttgt agatttgtat ataataaata
      301 tcttgctaaa agaatagatg tttataaaaa cgataaagaa acttttactt ataaacagtg
      361 tagttctgat ttgaccaatt taaaaaaaga attaaattgg cttaaagaac ctgacaaatt
      421 ttcactacaa aacgccttaa aagatttaga taatgcatat gaaaaattct ttaaagaaaa
      481 ggcaggattt cctaaattta aatcaaagaa aattaataga ttttcatata aaactaactt
      541 tacaaatgga aacattatgt attgtggtca acatataaaa ctacctaaac ttggtatggt
      601 taagataagg gataaacaag tacctcaagg tagaatactt aatgccacta tatctaaaga
      661 accaagtggt agatattatg tatcattatg ctgtactgat gtagatattg aagtatttga
      721 aaatactaac aatcagatag gtttagattt aggaattaaa gaattttgta tctcaagttg
      781 tggagagttt atagaaaatc ctaagtatct taagaagtca ttaaacaagc ttgctaaatt
      841 acaaagagaa ttatcgagaa aaacaatcgg tagtttaaat agaaataaag caagattaaa
      901 agttgcagga cttcaagaac atatagctaa tcaaagaaag gattttttac aaaaattatc
      961 tactaaatta ataaaagaga atgatattat ttgcatagaa gatttacaag taaagaatat
     1021 gattagaaat cgtaaactat ctcgcttaat ttctgatgtg tcatggtcag agtttattcg
     1081 tcaattagaa tacaaggcta attggtatgg tagacaaatt gtaaaggtgg gtaaattctt
     1141 tgcaagttca caaatatgca ataaatgtgg gtataaaaac gaggaagtta aggatttaaa
     1201 tataagagaa tggatttgtc ctagttgtaa tgaaactcac gatagagata taaatgcaag
     1261 tataaatata ttaaaagaag gattaagact aataacaact caaaataaat aacttatgta
     1321 agaaccgtag gaactacggg gatagcctgt ggagaattag taagacatat tttagtatgc
     1381 aaaattctgt gaagcaggaa ccctgtgact ttagtcatgg gaggttcagt ttgggcaagt
     1441 agtttcttgt aaatctagtt atgtttcaac caatgataat ataatttcat tagtattagc
     1501 tggtaattaa gttaatttga ctagagataa gtaaattgat ttaaaaggaa ataagtaaat
     1561 caacaattaa atacatctaa aagtaagttt attgcaatga attgttaaag aaaataatta
     1621 atatggagta aatctattgc aatgaggtaa caaagaaaat aattaatata gagtaagttt
     1681 attgtaatga attgttaaag aaaataatta atatagggta aagctattgc aatgaagtaa
     1741 caaagaaaat aattaatata gagtgaactt attgcaatga atcaacaaag aaaataatca
     1801 atataaaaag gagaaatatt tatgaataca ggatttccaa aagacttttt atggggagca
     1861 tcatcttctg catttcaagt ggaaggagct tgggataaag acaataaagg aaaaaccgta
     1921 gccgactata attcttttaa aaagtctcat ttacaggcag atactaaagt cgcatcagac
     1981 ttttaccata attatgaaga agatattgaa ttaatgaaag aattagggat gaaaacatat
     2041 cgtttttcaa tttcatgggc aagaataata ccagatggtg aaggagagat aaaccagaaa
     2101 ggtttagact tttataataa gataatagac aaactaatag agtgtgatat tgagccattc
     2161 gtaactttat accattttga ccttccattt aaattagtag agaaatataa tggttgggaa
     2221 agtagagaaa ctgtctatgc ttttgaaaga tttgctaaaa tatgctttaa gcattttgga
     2281 gatagggtaa agtattggca acctcataat gaacagaatt taattgttag agtggaggag
     2341 agaattaata tatatgatga aacagattca tggaagatag ataaaatgcg tgctcagatg
     2401 gattataatc tttgtttagc acatgcatta gcagttaatg catgtcatga gatgataaaa
     2461 gaaagtaaaa ttggagcagc agtatcatca tctgtaacat atcctcttac ttctaagcca
     2521 gaagatgtat atgcagctag aatgaatgat aattttaaag tgtactatat gcttgatatg
     2581 catcattatg gagaatatcc agggtattat atgaagtatc ttgaaaaaag aaatatagtt
     2641 cctcacatgg aagatgggga taaagagata cttaaaaaag ctaaaatgga ttttatagct
     2701 gtaaattatt ataggacaaa ttgtgcagaa gctttacctg aagattcaca acatccattt
     2761 ggattaagag aaggaactgt tgattttagt atgtatggac tatttaaaat gtcaatgaat
     2821 cctaacttag aggcttctga gtatggagca gcaatagacc catcaggtct tagagttgcc
     2881 ttaaatgaat attggcaaag atatcactta cctgttataa taacagaaaa tggtctagga
     2941 gctaaagata tattagaaga tggaaaaatt catgatgact atcgtataga ctatttaaga
     3001 agtcatataa atgcatgtaa actagctatt gaagatggtg tagagatgat tggatattgt
     3061 ccatggtcat ttacagacct tttaagttct tctcaaggtt ttaataagcg ttatggactt
     3121 gtttatataa atagaactga ccatgaaatt ttagatttaa aaagaatcaa gaaagatagt
     3181 ttttactggt ataaagaagt tatagagaac aatggaatag taaaataaac ataaatatat
     3241 attgagggtt ttagtatgta cattacaaag gtattaaata attcgttgct acttgcaaag
     3301 gatgataatg atgaagaaat aatattgatg gggaaaggca ttggccataa ttataaggcc
     3361 gggtctgagt taaataaaaa agatatagaa aagatttttg ttcttcatga tgaaaatata
     3421 aaaaagagca ttatacaatt ggcaacagaa atagatgcag aatattttgg tatagctcaa
     3481 atgataattg catatggaat agaaaaatat aacttaaaac ttatgaacca tatatatttg
     3541 gccttaactg accacattgc ctttgcagtg agacgtttta aagaaggtat aatgattgaa
     3601 aatcactatt tgttcgaaat caaggaattt aatccaaaag agtatgatat aggaaaatat
     3661 gctattactg tttttaagga ggttcttggt ttagacctac cagaagaaga gattggtaat
     3721 atagcaggcc attttataaa tgcacaacaa gataatcctt atagtgatag aaataagaga
     3781 agtgctaaaa ttgtaaatgc tattttgcaa atagttcatt atcacttttc tattgtatat
     3841 aataaagagt cattttatta taggagattt gtaatgcatc taaaggcctt ttcacaaaga
     3901 tttctggcta atgaaccatc aagagaaaaa atagatttta tatatgagca agttcaaaaa
     3961 aattgtaagg aagagtatga atgtgtgaaa aaggtaggag cttatatgta taaggaatac
     4021 tccagagaat taccaagaca agaggagtta tatttgatga ttcatattca taagatttta
     4081 ggagaattat gcgaaaatag ttagaatatc ttaatatgct agtaatatta taaaaaatta
     4141 aaaattaact gcactttaaa tatgaataat tgcattactt aagggggttg tcttaaaatt
     4201 gattttttta attaaatttg aagctcaact ccttttttaa acctttatat cattacaact
     4261 ttaatgttta tacgcctgta cttcagatgt atatctactt tttacatttc tcaacatgca
     4321 aatctaccat tttttgcagt atgttagcag tatgttaatt gaaataaact attgagttaa
     4381 ccctaaattt attctggact tataggaata gttccaaaga tactttaaaa tattttctgg
     4441 aatgattgct tatttcacat atgttttatt gtgatgtttt gatttaataa attcttcaac
     4501 tctgtatata gtaaatgtat tatcatgttt gttttattca agcacactta taatacgctt
     4561 gattttttca caatgatgaa atatactaat gggtgttata ggtataagaa tagcattaca
     4621 cttgaagaag caagtgataa atgagatata aatcctcata tgataaacta ctatttcatt
     4681 gaggaacata ttctaagtga tgtcaagata ctacaatatg actaaattcc tagtgataaa
     4741 aaagtctacg aatgagtgta gaaaggggaa ctaagatgaa taaagtttta attatagatg
     4801 atgataaaga tctttgtatt ttgttaaaaa agagtatctc aattgaacag attgaagcaa
     4861 actattgcca ttctgggaga gatggactgg ttgaactttc aaaacaagat tatcagttag
     4921 tagttctaga cgtgatgatg ccaggtatgg atggttttga aactatggaa caaatacgaa
     4981 aatatagcag tattcccatc ttaatgctga catcaaaaag cgataattac agcaaagtgc
     5041 atggattgcg agctggtgca gatgactatc taaccaaacc atttgaaatt acagaattta
     5101 ctgctcgtgt actgtcttta atccgacgtt acacccgttt taatccaaaa aatgaggaac
     5161 cacagcaact ttctttcaaa ggtttgttga ttgaccttga ccagcataca gtgactacca
     5221 atggcgaacc tatgttgctt ccacccaagg aatttggtgt acttctttac tgtgcaaggc
     5281 atcagggtaa gattttgaca aaacagcaga tttatgaagc cgtgtggggt gagccatatg
     5341 tatatgatga cagcaatatc atggctatta tcagtcgcct aaggaaaaaa attgaactag
     5401 acccatcatc tcccatctat ttgcaaacaa taaaaggaat tgggtatcaa ttcaacacgg
     5461 aggtatgaaa atggatgaac aaacgataat tcttttctta ctcttgctgt cgattggtct
     5521 actttttctt tccatatttg ctttttccaa gcttgggcat atttacaagc gcctaaaaga
     5581 tatagaggag atactggctg atgtacaaat tggagacgaa aatcgtaaaa tactaattaa
     5641 gccatatgat gttatggctc cattggttta tcagcttaat gagattgtct acgattatga
     5701 aaataagtta ctttctctga aaaagtcgga taaagctagc aaacaactta tgacaagttt
     5761 atctcatgat gttcgtacac cattaacaac tctgattggt tatctggatg ctgtacacag
     5821 tggtatagtt atcgaacaag agcgggagga ataccttgaa atcgctaggc gtagagccta
     5881 cgacctcaag gattacattg atgttctttt tgactggttt cggttgaact ctgatgaatt
     5941 tacgctgtca atagaatctg tggaaattgc agagttgtca cgcaatattt tgaaagactg
     6001 gattcctata ttccatgaaa agaaactgaa ttttgaaatt gatattccag aaaatcgact
     6061 aatggtaaac ctcgaccgag atggatattc ccgtgtggtc aataatctgg ttcaaaatgt
     6121 tcttgctcac agtaaggctc ggcaaatcaa aattaccatg agtgaggatt ccagaatggt
     6181 attactccgt gttgaggatg atggtgttgg gattgccaga gaaaatttac cacatatttt
     6241 tgagcgactg tataagtgtg ataaaggacg ttcagaaaaa ggaagtggtc ttggtctatc
     6301 tattgtcagt caaatggtgg agcgaatggg tggtcagatt tccgtagaaa gtgagattgg
     6361 aaagtatacc atatttacag tgagcttacc attaatataa aattgttttt cccccatgtg
     6421 acatgtatac acagggggat tttttgtaag ttataaagtt gcaaggttaa tacaaggttg
     6481 ttgcaaggtt aatgtaagat tgaggtggta tgataacttt aataaacaaa ggaggctttt
     6541 attatttatg aataatttaa ttattgaaac aaaaaatctc actaagcaat atggtgctca
     6601 aaagagcgtt tctaatttga atattcacgt tcagaaaggt cgcatttacg gattgctagg
     6661 aagaaacggt gcgggtaaga cgacaactat gaaaatgtta ttgggtctaa caaaaccaac
     6721 tactggagaa attaaaatat ttggtcagga cattcacaat aacgagaaga agcttcttcc
     6781 tcgaattgga tgtttgattg aatcaccagg gttttatcct aatctgacag gaacagaaaa
     6841 tctcaaaatc tttgcaaggc ttagaggaat accaaaaaaa aatgcagtag aatcagcact
     6901 ggatgtagtc ggtttgccaa acaatgacaa aaagttattt tctcaatact ctcttggtat
     6961 gaaacagagg ttggcgattg ctcttgccat tatgcatgac ccacaactgt tgattttgga
     7021 cgagcctatc aatggacttg atcctattgg tattgcagaa gtaagaacgt ttattcgtga
     7081 tctctgcaca gaacgaggta aaactatttt gatttccagt cacattcttt ctgaaattgc
     7141 cttgttggca gatgacattg gcattattga ccatggtatt ttgttggagg aagaaagtct
     7201 tgcccaatta gaagaaaaaa acagtaaata catacatttt gctgtatctg atgcagcaca
     7261 ggcagcaagg cttctggaaa cccaacttaa cctgaaaaat ttcaaagtag cagataatta
     7321 caatattatg ctatatgata cagatgtttc tgttgcagaa ataaatcgtg ctttcattct
     7381 aaacaacatt gaggtatcag aatctcattt atgcgaagat actcttgaag attacttcaa
     7441 gaaagtaaca gggggtgaag gaattgcttg atataatttc atgcgaattt tcaaaactca
     7501 agcggttaaa atttatactg atttctattt taggtgcttg cttatttcca attcccgcaa
     7561 caattttgat tgcaaaggac aacttgccct ttgagcaatt gttcaaatta gttgtcaatt
     7621 ttggatattt tttgctatta ccaattgtat tgagtattgt tgctagccaa ctatttttca
     7681 tagaaagaga taacgatgta ttaaaaaatc ttgcaacagt gccagtgtca aaaggaaaac
     7741 tggctctggc aaaattggct gtgttgctgt ttatatcatt gttctactcc gttgcaggat
     7801 taggagctac tatcattgga ggtttcattg ttggaatagt agagggggtt gctgtaaaat
     7861 taggaatgag cattgctttt ggaattatgt tttttgttac tgcacttcct attgtggtac
     7921 tcattgtata tttcaatcgt agctatattt tttctattat actttctttt gtatatgcta
     7981 ttttcaattt tagtatatcc ttaaatatta tcaattttga gccaaataac ccactattaa
     8041 gcgtattacc tgctcctgtt ataatgcgtt ggtggatggc attttgggga gatcccactg
     8101 gcgaatacac ggcacttaga cagccatatt tgctctcaac ttctgcttgt gtaggtattt
     8161 tatgtttgat aaccattata gcagtcctgc tgatttgtat gatatacaaa aagcaggaga
     8221 attaggaggt atctatgctt gatataatta ctacagaatt tcaaaaaata aaaagatata
     8281 atattctatg gattggtgtt gttgctgttc tgttttcagc actattggca gtttttcaga
     8341 ttgtaagttc acacggcagt gaccctctaa cgtatgagag ctttgcaaat ggagttatct
     8401 ggaataattt cagtcttagt tttccatttg ggattacact tattggagga tatcttatta
     8461 accgtgaata tacagaccaa accttaaaaa acatcctaac tgttcctatt tcattacgca
     8521 aattgctagt gggaaaatta attgcggttg gaggaattac tgtattgtta agtcttttca
     8581 gcttcttatg cacatttatt ttggggttgc tattttgcaa tatcaatata tctgttacac
     8641 tagttgcaaa atccttagtt cagattttgt ctgttaatct gtattgttat gttgctgttt
     8701 tgccgattat tgcttatttt ggtcgtaaac aaaatgcatt tctgacgggt gtagggattg
     8761 catttgtata cggtttttgt ggtgtgtttg ttgctggaag aaatctgaca gacttttatc
     8821 caataacagc aggtcttggt ctagttggat acaacaatgg tgctggtact gtttatcagc
     8881 cacttatcgg tgctatgact ttgattgtaa ttctaatctt gacaactatt ctacttgtat
     8941 ttacacctaa ttacgataaa gttatgacca tatctaagaa aaaagggata aagcataaaa
     9001 agtattctca taaataacat aaatattgtt tctattactt aagttgctag acagtgaaaa
     9061 gaaaaaatct gtcgtacagt ggctatatgc tcatgtattc aagaagctac agttttgatt
     9121 tttcataact atagcttctt tgttgtattt attaaatcac ggctatcata atacttgcaa
     9181 taggtatagt aacaagagag agtactgtca tgtgtgtttt atatattaca ttaagtatat
     9241 tctaaaatat atgttttaaa taatatattt gaaaatagga atatttaaat aaaaaaaata
     9301 atattatata tagttgacaa aaattggcaa atgatataat atataaatat agaaatagta
     9361 atcattacta ttattaaaaa gggaggaatt aattatgaac ttaaaaggaa ctaaaacaga
     9421 aaagaattta atggcaggat ttgcaggaga gtcagaagca agaaataaat atacatacta
     9481 cgcttcaaaa gcaagaaaag aaggttataa tcaaatagct gctatatttg aagaaactgc
     9541 taacaatgaa aaggaacatg ctaaattatg gtttaaactt ttacatgatg gtatgccttc
     9601 aacagaggaa aatttaaagg atgcagcagc aggtgaaaac tatgaatgga ctgatatgta
     9661 tgcaaaattt gctaaagaag ctagagaaga aggatttgac aagatagctt atttatttga
     9721 agctgttgga aaaatagaga aagagcatga agaaagatac ttaaagcttt tagaaaactt
     9781 aaatgaagga aaaatattta aaagagatga agaagttgtt tggcaatgtc aaaactgtgg
     9841 tcatgtgtat gtaggtactg aagcaccaga aaaatgccca gtatgtgacc atccaaaagc
     9901 atattttaat ataaaagctg aaaattatta aaaattatca ttattaaaaa ggaatgttaa
     9961 ctatgaaatt ttctaaacaa cgagaactga ttttaaatga aatattaaat aatccggttc
    10021 atcctactgc ggattaccta tatgaaaact taaaaaaaga taatccaaat ttaagcttag
    10081 gaactgtgta tagaaattta gctcagctaa cggaacatgg ctttataaga aaggttagta
    10141 ttccagggta tccagataga tttgatggtc gaatagataa tcactatcat atcatatgtg
    10201 aagtatgtgg agaggtatac gatttagaat ccgaagttct taataattta caagaattaa
    10261 tatctgagga gacagacata aaaataacat cttataacat aagttttaaa gggatttgta
    10321 ataattgtaa aaggtgtagc caagtaggtt agttttcaaa ttctaaaaat aattaatgag
    10381 gtgagtttat gtgtagtgaa caaaaatttt ttatatgtga gacttgtgga aaccttgtag
    10441 gaatgataca aagtggtggt gtacctattt tctgttgtgg aaaacctatg aaggaacttg
    10501 ttcctaatac aacagatgca gcagttgaaa aacatgtacc tgtaattgaa gtggatggaa
    10561 ataatgttac tgttaaagta agtagcacaa ctcatccaat gactaaagaa catcatatag
    10621 catgggtgta tcttatgact gaacaaggtg gtcaacgcaa atgtctagca gtagatggag
    10681 aacctgtagt taaatttgct ttgaatgatg atgataaagt gatttctgcc tatgcttact
    10741 gtaatttaca tggattatgg aaggctgaac tgtaatattt aaataaattg agtcaaaaag
    10801 gaggctataa atgtattttc atacaaatag cctcctataa atttatataa attcaagttt
    10861 taattttgtt taatgtcaat ataatataag gagaaaataa tatgtcaatt tataaatgta
    10921 gtgtttgtgg atatatttat gatgaatcta agaatgataa aacatgggat gaattaagtg
    10981 aagattggga atgccccgta tgtacaaaag gtcgtagtta ttttggaaag ataagtactg
    11041 tttactatga agaagatgaa aagatagcag aagacatagt tgaagatgaa tctaaattaa
    11101 atactgaaaa agagggagat ttaaattact taagtacata tttaagaaga gatgatgaag
    11161 ttgagaaaca tatggatata attcacgaaa tggctgttac aggaaaatct ataatagaac
    11221 ctatgagaac taaactacca gtaatttctt gggatgatat tttaattatg ggtgctcaat
    11281 taaatccatt acctttaaat gagcatgatg aagtaaatac aacaacaata ataggaaaaa
    11341 aagcaaagaa acctatgatt atagaaaatc cagtttatat ttcccacatg tcatttggag
    11401 ctttgtctaa agaactaaaa atagctttag caaagggtgc agcccaaaat aagacagcta
    11461 tgtgtagtgg tgaaggaggt atattaccag aagagaagga agcttcatac aagtatattt
    11521 ttgagtatgt accaaataaa tatagtgtaa ctgaagaaaa tcttaaaaat tctgatgcta
    11581 tagagataaa aattggtcaa ggaacaaaac ctggtatggg aggtcatctt cctggcgaaa
    11641 aagtaactga agaaatagca aaagtaagaa ataagcctgt aggtcaagat gtaataagtc
    11701 catcttgttt tgaggaaata caatccaaag aagatttaaa gaaacttgta gatgaactta
    11761 gagaagtttc agaagggcgt ccaataggtg ttaaaatttc agcaggtcat attgaaaaag
    11821 atatggaatt tatagcttat gctaaacctg attttgtaac tattgatggt cgtggtggag
    11881 ctactggagc aagtccaaag ttgcttaaag atgcaacttc aattccaaca atatttgctc
    11941 tttatcgtgc tagaaaatac atagatacac atggattaga tatagatttg gttataacag
    12001 gtgggcttcg tatatctact gattttgcta aggcaattgc tatgggagct gatgcagttg
    12061 ctattgcaag ttctgctctt atggcagcgg cgtgtcaaca atatcgtata tgtggttctg
    12121 gtaagtgtcc tgtaggagta gctactcagg atgaggaatt gagaaaaaga ttacatatag
    12181 aaaatagtgc taatagagtg gcaaactttt taaatgtaag tttagaagaa cttaagactt
    12241 ttgctagaat ttctggtcat aaagatatac atgatttaag tgttgatgat ttatatactg
    12301 ttaactctga aatatcaaat tatacaaaca tacagcatgt atagattgaa gtttgaaact
    12361 attagatttt agatagctat aaaagtaaat gataaatata ttttataaaa gagagtgtct
    12421 taaaatgaac tttttagttc ataagtcact cttttttgta tgaagccaaa tatatttatc
    12481 attttagcaa tgaaaaagaa tcttatctct ttattttgag atagactcct tctatttatg
    12541 aaaattaaag atattaaatt gtaaaatatt ctgtgatgtc gtactattaa actaaagatt
    12601 ctgtacttta aagtaaataa aaatttaagg agtgattatt atggaaagat tgaagataca
    12661 agttttagtc gacaataata cttatattga tagatacttt gttggagaac cagcagtaag
    12721 ctattatatt gagattgatg gaaataggat tttgtttgac tcagggtatt cagatgtatt
    12781 catatcaaac gctgaaaaat taaatataga tttaggaaat ttaactcatg ttgttttttc
    12841 tcatgggcat aatgaccata caagaggtat ccagttttta gaaaataggt atgatttatc
    12901 tacagttgaa cttatttcac atcctaactg ttttatacct agaaaacatg gagagaaaag
    12961 cataggagct ccattttctg ctgaggaaat taaaaatatt tttatgtata atcctaagga
    13021 taagccattt aatctaagta agaattgtgt gtttttaggt gaaatacctt ctataaatga
    13081 ttttgaaaaa agagctaaaa ttggtaaatg taaaatagga gatttgtggg aagatgatta
    13141 tgttttagat gattctgcta tagtttgtaa aactgataaa ggtattttta ttgttacagg
    13201 atgttctcat agtggaattt gtaatatagt agagcatgct aaaaaggtat gtggagatga
    13261 tagagttatt ggtatactag gtggttttca tctttttgaa ttgaataata ggttagatag
    13321 tacaatacaa tatttggata aagaagaaat aagaatgttg tacccttgtc actgtgtttc
    13381 ttttaaggta aaagcgaaga tgaatgaaat attgaatata aatgaagttg gagtagggct
    13441 gaccataagt atatagtatt tgaaagtata taagatttaa gttgaaggtt aaaaagatat
    13501 tttctataga aaatatcttt tttgttacgt ttattttaag agaaatcaat atacttttat
    13561 atgaaatatt gtaaaaaaat ttatttttaa tgagaatata ttttcattaa taaacaatt
//
LOCUS       DAEPXW010000098        13486 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.100, whole genome shotgun sequence.
ACCESSION   DAEPXW010000098 DAEPXW010000000
VERSION     DAEPXW010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13486
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.100"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            251..2110
                     /locus_tag="KRM55_002958"
     CDS             251..2110
                     /locus_tag="KRM55_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1595173.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2402..3001)
                     /locus_tag="KRM55_002959"
     CDS             complement(2402..3001)
                     /locus_tag="KRM55_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1595174.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3104..3901)
                     /locus_tag="KRM55_002960"
     CDS             complement(3104..3901)
                     /locus_tag="KRM55_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-binding protein"
                     /protein_id="HBH1595175.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPASLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(4014..4119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4211..5197)
                     /locus_tag="KRM55_002961"
     CDS             complement(4211..5197)
                     /locus_tag="KRM55_002961"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH1595176.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5681..7411
                     /locus_tag="KRM55_002962"
     CDS             5681..7411
                     /locus_tag="KRM55_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBH1595177.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7521..7601
                     /locus_tag="KRM55_002963"
     tRNA            7521..7601
                     /locus_tag="KRM55_002963"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7555..7557,aa:Leu,seq:tag)
     gene            7936..8451
                     /locus_tag="KRM55_002964"
     CDS             7936..8451
                     /locus_tag="KRM55_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HBH1595178.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKI
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8943..9047
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9257..11731
                     /gene="gcvPA"
                     /locus_tag="KRM55_002965"
     CDS             9257..11731
                     /gene="gcvPA"
                     /locus_tag="KRM55_002965"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBH1595179.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSILRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYIATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11731..13188
                     /gene="gcvPB"
                     /locus_tag="KRM55_002966"
     CDS             11731..13188
                     /gene="gcvPB"
                     /locus_tag="KRM55_002966"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBH1595180.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         5073 a         1594 c         2210 g         4609 t
ORIGIN      
        1 ataattttaa taggtggttt gtaattaaaa agtttataaa ttacattaag agtaataatc
       61 tataagaact tatatattag aaaaaaattt ttgtatatat agaggactct aaagatgaac
      121 tatgtaaaac aaggtttata tattctaata gtatagcaaa atttattgta aacgcatgta
      181 tattattaga aaaaatagtt tgaaggtatt caataaacat aaaaaacaat ataggggata
      241 aaggtgtttt atgaagagat ttttgaggag aattatctta gttttattta ttttgttgat
      301 ttttataagt tttatttcta ttaaattaat tcataatgtt ggagattatg gaaaattgat
      361 taattatgtt gggattgttc gtggagctag ccaacgtcta actaaactag agatgaatca
      421 tcaaccaaat gatgaattaa tagaatatat tgatgaaatc ctacaggagt tgattacagg
      481 gcatggagat tatggtttag taatcactga ttgtaatgaa tacaatgagg acttactttt
      541 attagaaaaa aagtgggaag atttaaatat tgaaattaaa aaagtaagaa tgaaagaaca
      601 gaataaccag ttattaagta taagtgaaga gtttttttct cttgcaaatg atacagtgtt
      661 taaaatagaa aacttttcta aagaaaaaag taattactta atgactttaa taataattat
      721 atctattata ggtatattag catgtatcat attgatttta caatatagta aaaaaatggt
      781 tagactggaa aaattaaatg tagatttaaa aaatattgca tataaagatg aactaacagg
      841 agtaaatact atagaaaaat ttaaattgga tgcaaatcaa aatatttgta tacataagga
      901 taagaaattt gctgtattct atattgattt tgaaaacttt aaatacatta atgatatatt
      961 tggatatgat tatggtgaca tgatactgaa aagatatgct aatcttatga tgaatgacat
     1021 agggaaatat gaaatatttg caagagaaat tgcagataga tttgttgcgt taagatgcta
     1081 tgtagataag gaagatttag tggtaagaca acgagatgta gacaatgaac taattaatat
     1141 aacaaatgaa attaaaaata aacatagtat tactgttgtt agtggaattt gttgtattga
     1201 agatgtaaat gaaaaattaa gtatagatgg tttaataaat agagcaaatt ttgcacaaaa
     1261 gactgttaag aataaaccag gtactaatta tgctttttat aatgacagta ttcgtaaaaa
     1321 aatgattgaa gaaaatacta tcaagagtag aatacatgaa gctattgaaa aaagagaatt
     1381 tatagtttat ttacagccta aagttaattt acatagtcaa aaaataaatt gtgcagaagc
     1441 tttagttcgt tggcttactc cagataaagg tattatatcg ccagcaatat ttattccagt
     1501 acttgagaag aattttttta ttgccttagt agataagtat gtttttgagg aggtttgtaa
     1561 atggattaga aagaggttag atgaaaataa accttttgtt cagatatcag ttaatgtttc
     1621 aagaatacaa ttttataaca ctaaatttgt agaaacttat tccaatatac aaaataaata
     1681 caggatacct aaaaatacta tagaaattga atttacagag agtgttgctt ttgagaatca
     1741 aaaacatctt ttggaaatta tacatgattt gcatgaaaat ggatttactt gttctttaga
     1801 tgattttgga aaaggttatt cgtctttaag tgttttaaaa gatttaccat ttgatgtttt
     1861 aaagcttgac tctatgtttt tcaaggctag tttagataaa gataaagaga aaatagtaat
     1921 aaaaaatatt gtacatatgt taaaagaact taatatcaca actgttgctg aaggcattga
     1981 atgcaaggaa caagttgaat ttcttaggga tattgggtgt gatttagttc agggatttgt
     2041 attttataaa ccaatgccaa tattagaatt tgaaaaaata ttggataaag agtttgttta
     2101 taatagctaa aatgtacttt ataaaatatg aactaattaa gtaaaattat tttgtactga
     2161 ataaattttt actttattta cagaataatg attatttaca gaaaagcgcg aaaagtgtat
     2221 tcctttaagt gtgggatgga tagcacaaat aggggagaaa aaatattggc catataagaa
     2281 tgcataataa tataaatatt tgaaaggtca gcatcatata aaaattaaaa agaaaataaa
     2341 taatttttct ataaaaaaga gactatgaga aaatttactc atagtctcct aaataatgta
     2401 tttattttct tcctgcaacc cattttaatc cccaatgaaa ttcagtatcc atttctctat
     2461 gacctttgaa gtatttaact actttttcaa cactgaatgt ctcatcattt acattttcta
     2521 tcaatgctat tgaacacata ttatagccat ttttatgttc atcaagtttg acaactaagt
     2581 ctgaatcttg tttttgtttg attgttacaa ttccatcagc ttcagaccag ttagctacac
     2641 cttcgtatat aaaagcataa ataagtattc tttttatatc ttttatttta ttaccattta
     2701 ttcttaaatt ttctccttgt gtattacttc ctgttctgtc atctccatct aattgagcaa
     2761 aaggtggatt gtctaaacta ccaaaggcat ttcctaatgc ttgaacagca ccttttacac
     2821 catttttcat ctcaaatagg caacccaaat ctaaatctat attactgctt ctcaaagagc
     2881 caaaaaaacc ctttttttgt actttttgat tccaatttaa attaactaag atttcaccta
     2941 aatcgctatt ttcctttttt gtaaggttta ttttttgtcc cttttttaat tctatagcca
     3001 tagtaatctt cctccacaaa catagattta tttaaatggt agcacttaat aagtcaatat
     3061 tcaacaagat tagaataata atattaaaat tatactaaat atactaaaaa gtaggaatca
     3121 caataccttt gtatttttct tcaattaagc ttcttgcttt atctgatgta agaacatctt
     3181 gtagaacttt aatcttttca ctgtctttat cttcagttct aaatgctaaa agatttgcat
     3241 actcgtcatt tataggagct gtataaattc cgtttttctt ggcatcaaga ccagcaggta
     3301 cagcataagt agtatctata aatgcagcag tcacatctgg aagagaagct ggaatttgag
     3361 caatatctaa ctctttgaat tgtattccct ttggattttc tattatgtcc ttaggactaa
     3421 ctaatccatc ccctttaggt aacgttaaaa gtccaatact ttcaaggtat ctaaggttct
     3481 tagaacaaga agatgggtta ttgcttattg caattgtatc tcctttttta aattcatcaa
     3541 cagattttat cttataagag taaagtattg ctgggcatac atatagtttt ttaccagcca
     3601 ttattttgta acctttggcc ttaacagctt cttttagata aggttcatgt tgaaatagat
     3661 ttgcatcaat ttcaccatta tttaaagctt cgtttggaag tatgtaatca tcaaagtttt
     3721 taacttctaa agtatatcct ttttctttaa taagtggttt taattcttct aataactctc
     3781 ctcctggaac taaagtagca ccaacaacaa tttttttatc atctttagct ttagaacatc
     3841 caaccacagc taaagttaat actagacata ataacaaaca taataatttt ttgaatttca
     3901 tataaattcc ctcctgaata taattgatta gttaaaaata aaataccatt ctttatcaca
     3961 ctgcaaaata aaaataagcc tgagtttaaa ctcaggcttt aaaagctaat ttagactcat
     4021 ctttcagtat aatactgcag gatttagcac caatgtatat aaaaatatac tggttgctgg
     4081 gtttcatagg gccagtccct tcaccactct ggataagaag tatcaatttt taattatgtt
     4141 ataaatatta tcatgatttt ttacgtctgt aaacataatt ttataaatat tttaaaatct
     4201 ttaatgtatt ttatttaaca cctaaaattc cagaaactag aatatcagta tcagcaccta
     4261 agaaatagtc atttatttca atagaatcca gagtatttct caaagcattt tcttcatgcc
     4321 ttataccaat aagtttattt tctacaaatg caacatcaca ttttccaaaa aaatctccaa
     4381 aaaattttat actagttatt atgcctttat caacatttaa attaaactca acatttccac
     4441 cagaatattt taattcattt gaaagagtat attttggtga attaccaaaa ttccaatccc
     4501 aagtttcgta ttttgattta gtaagctttt ctatttgttt tatatcatgc tcactcaaac
     4561 aataattagt attatcagta tttgttttag aaagataatc cattatagca tctttaaatt
     4621 ctaatatatc catttttgaa tgtaaatgtt cacttatatt ggttacacga gattttacag
     4681 attttattcc ttttccttca aattttatag gtttaacctt taatgctttt gagaggtcat
     4741 ttatttcaga tgaaaataaa agagtcccat gatgcattac tttgtttttg tagttgtatt
     4801 gagcatttcc agaaaatttc ttgccatcta taagaaggtc atttcttcca gaaaattcgg
     4861 cattgacatc tagtgtttta agtaaatcta ttatgggctg agtgaatctt ctgaaatcac
     4921 taaaattatt attgttacaa gctataaatg taaaatttat atttcccaaa tcatgaaata
     4981 cagctccacc accagactgt ctcctaacga caggtataga atattctttt atatattcta
     5041 aatttatttc agaaagtgtg ttttggtttt ttccaacaat tatagaaggt tcattcctcc
     5101 ataaaataaa taagtcttca tcaaaatttt ttagaagata ttcttccatt gctaaattaa
     5161 aataagggtt tgttttttca ttataaatta ataacattaa agtagttcct ccatagaatt
     5221 gataaaattt ttattatgaa tacaattaat tttataattc gacaataata taaaaactcc
     5281 tttaaattag aaattttaaa aactaccttg caaagtttaa ataaataata tatactcaaa
     5341 atatgtttaa taaaagtgaa tagaagggta gaggcgcaat aatctatcag tactaataag
     5401 gagttaagca cagagattta ttaggaaagg agatattgcc gaagttttat aatcgatgct
     5461 ttaagattat attgctgggg gtacatagaa aatatgtaca actgtcacag gtttatttgt
     5521 ggtgagctat catttaagga attatattat atttattttt actattgttg atatattgta
     5581 atgtttaagc cttgagtgtt taccactcaa ggctttttta gttttattgt aacataatac
     5641 cctgtacagt tcacaaaatt aaaaggagag ggagatttat atgaggaaca aaaaaattaa
     5701 tattattttt ctgacgacaa tcatgttcat aatgtcaaca gtaatggttt ttgcagaaga
     5761 agatatagac actattgcac tagccaatgc agaaaaattt gggattttaa ctttaatacc
     5821 accattagtt gctataatac ttgcatttat aactaaaaac gtaataattt ctttacttat
     5881 aggtattctt tctggtagtt ttataattaa agctagtggt attaatgttt ttgcgacatt
     5941 tatacaggca tttttagatt tagtagacag agctttagta tctttagcag acccttggaa
     6001 tgcagggata atactacagg ttttggcaat tggaggagta ataaatcttg ttgctaaaat
     6061 gggaggagct aaagctatag ctgaagcact tgctaaaaga gcaaagtcag caaaagggac
     6121 acagcttata acatggtttt tggggctttt agtattcttt gatgattatg ccaattcact
     6181 aatagtaggt cctatgatga gacctgttgc agataaaatg aaaatatcga gagaaaagct
     6241 agcatttata atagatgcca cagcagcacc agttgctggt ttagctataa tatctacatg
     6301 gataggtctt gaggttggtt taatacatga tgcttttgaa agtataagta tagatgtaga
     6361 tgcatttggt atatttttaa atacaatacc atttagattt tacaatatat taatattagc
     6421 tttcattgta atatcagcat tattattaaa agaatttggt ccaatgagaa aagctgagat
     6481 aaaatctaga agtagaaaaa ttagtataga ccttgatgaa ggcgtagaag agttggatga
     6541 tttagctcca aaaaatggag taaaattgag tgtatggaat gctataatcc caataggaac
     6601 attgataata gttgcattag catcatttta ttatagtgga tatacatcta taatgggagg
     6661 agacgataag gctctgatac aactatttac aaattctcca tattcttttg aagcaataaa
     6721 agaagcattt agtgcatctg atgcatctag agcattattc cagtctgcac ttgttgcaag
     6781 tttagttgct attataatgg ctgtagtaaa aaagattttt acaatatcag aagcaattga
     6841 tgtttggata gatggaatga aaagtttagt aatcactggt gtaatattaa tacttgcatg
     6901 gtcattaagt tcagtaataa aagagttagg tacagctaaa tttttaatac acctattatc
     6961 aggttcacta ccaccattct tattaccaag tttaatattt ggtttaggag caataatatc
     7021 ttttgctact ggaacagctt atggaacaat gggtatactt atgccacttg caattccatt
     7081 agcatactca ttaaatcctg atatgtctta tgtaatagta agtactagtg cagttttaac
     7141 aggtgcaata tttggagacc attgttctcc aatttcagat acaacaatac tttcttcaat
     7201 gggagctggc tgtaatcata tagaccatgt taacactcaa atgccatatg ctatatttac
     7261 agcagtaatc actattgtat ttgggtatat accagctgga cttggattgc caatatatat
     7321 agtattacca gtggcaatag ctgctatatt tgtaggtatt caaataattg gtaagaaagt
     7381 tgatgaagcg gaaatagaac ttgtagaata aagatataaa taagtttcac cttttattat
     7441 cactattttg ttagttttta gataatttta aaaagttatt gaaaataatg gcgaaatata
     7501 gtaaaataaa agagtgataa gcggatgtgg cggaattggc agacgcacta gacttaggat
     7561 ctagcgccat tggcgtgggg gttcgactcc cttcatccgc actttacagt acttaattgt
     7621 actgaaaaaa actggggttg ctggctttcg gagtgggcta tcccgttttt atttttttgt
     7681 atatataata gattggcact ttagtataag gtgctttttt tataggcaaa aacagtacat
     7741 ttatttctgt tttattatca ttcatctatt agaatatact ttagttaaga atgtgttaat
     7801 aagcagtgtt cacattcttg ataaaatgtg gaataatatg tatttttact aagacggaaa
     7861 tgaaataatt aaaccattaa ataatattat aagatgatga ataagtagat aaatcaaatt
     7921 ttgtaggagg atattatgga aaaatatata tggttgtttc cattactttt tatttttcat
     7981 gatatggaag agataatagg ttttggaata tggcttaaaa aaaataaatc aatgcttgat
     8041 aagaagtatc catttatcag taaaatttat gaaaattata gtactgaagg catggcattt
     8101 gctgtgtttg aagaatttat tttatgcatt attttctgta tacttacagt tataacagaa
     8161 aatcagtatg tatatctact atggttaggt agttttatag catatacctt acatttggta
     8221 attcatatag ggcagtcaat cataataaga aaatatatac cttcacttat taccagtatc
     8281 atatgcttac caataagcat ttggtgtata agtaagagta tttatatagt tgattgtgaa
     8341 atgagtacaa caattctgta cagtataatt ggcattataa ttgtagcatt gaatttaaag
     8401 tttgcacagt cgctgattgg aaaatttaca aagtggatgt caaacatata aattttagtt
     8461 tattggacag ttcaaggaat cagaaattgg aattttatag tattaatatt ttatggtatt
     8521 aatataatgt ataaaatttt atagcaatgt atttcataag tataaagtga ctagaatttt
     8581 aagaaatata caaattctat aaaaactaaa taatttcaag tatattttaa aaatcttatt
     8641 tttcacaagt ttaaaattgt aaacgatttc atcaagtcta tgaatatact tttaacatgt
     8701 tatagtaaat ctcaatataa atttacattt ggttctttgt gtgttatttt aataataaat
     8761 taagtgaaaa tgttatttta cattaatata taatatcttt gcataagagt gaataatata
     8821 aaagagaaat aattaataat aaaaacttaa caaaaaaatt aatacataaa aaaaaataaa
     8881 tataatgtgt tgacatttaa ttgaaatatt catacaataa aattgaaaat aaatatttcc
     8941 aaatgagatt agcgagagag tcctttatac gaaaaggcgc cgaagaagaa atttaagaaa
     9001 tgccaatttt tagagaagct ttcaggcaaa aatatcgcta attgatggga ctctggagag
     9061 acttaagtta agatactata agtcaccgaa gaagcaaaat aatattaaat tattaaatct
     9121 ttcaggtata caaacaggga tatataggct aggattattt tccatgctga tatatctttt
     9181 ttttatgaaa aagtacagga aataatatca aagttactta aatacagtag gtctaatttt
     9241 ctagggaggg ttatatatga atgaattgaa aagagtatct ttgtacaata tacacaaaga
     9301 gcttggagca aaacttgttg aatttgctgg ttgggaaatg cctttagaat atgagggtat
     9361 aaataaagag catgagaagg tcagaaaaag tgcaggtata tttgatgtat ctcatatggg
     9421 agaggtacag ataaagggag cagagtcaga aaaatttata caaaacctag ttacaaatga
     9481 tataagcgca ttaaagataa atgatattat atatacacct atgtgttatg aaaatggtgg
     9541 agtagttgat gatttattaa tatataaatt tggtgaagaa gattatttat tagtaataaa
     9601 tgcaggtaat atagataaag atgtagcatg gataataaaa caaagtgaag gatacaatgt
     9661 agatataaaa aatatatcta gtgaagtgag tcaattagca attcaaggac ctaaagcaga
     9721 agaaattctt caaaaaatca cagatataga cttaaactca ataaaatttt ataagtcaat
     9781 tccatcaaca aaagtatgtg gttgtccttg tttagtttca agaacaggat atactgggga
     9841 agatgggttt gagatatact gtaaaaataa atatgtagaa ataatttgga atgaagttct
     9901 aaaggttgga ggagaagata tatgtccagc tggtctaggt tgtagggata ctttgagatt
     9961 tgaagcagct ctacctctat atggacatga aataaatgaa cacatatctc caattgaagg
    10021 tggtttatct atctttgtga aaacaaataa agaatcattt attggcaaat caattttatc
    10081 aaaagaaaaa gaaagtggag ctaaaagaaa gttagtagga tttgaaatgc aaggtaaagg
    10141 aatgcctaga aatggatatg atataaggat tggtgataaa acagttggat ttgtaacaac
    10201 aggatgtgca tctccaacga caggaaaaat tttaggtatg ggaattatag attctgaata
    10261 tgcaaaagta ggaaatgaaa taggtatagc aatcagaaaa aaagttgttc ctgctgtgat
    10321 agttaagaaa cctttttata aaaaacaata taaaaaagat aatattatat taaacaaaga
    10381 aaataaattt tcatatatac ctgctacaag tgaagataaa tcaaaaatgt taaaagtagt
    10441 tggattaaat tcggttgatg aattattttc agatatacca gaagaagtaa aattaaaaag
    10501 agatttaaat ttggaaattg gaaaatctga attagaggta agcaaaatag taaaaagatt
    10561 gtcagaagaa aatttaagtt tagaagactt gacttgtttt cttggtgctg gtgcatatga
    10621 ccattatata ccatcaatta taaaacatat aacttcaaga tctgaatttt atacagcata
    10681 tactccatat caagctgaaa taagtcaggg aactttacaa gtagtttttg aatttcaatc
    10741 tatgattgca gaaattacag gtatggaaat tgcaaatgca tcaatgtatg atggagcaac
    10801 tgctgcaata gaagcatgta taatggcaat gaatcagact agaaaaagta aaatagtagt
    10861 gtcaaaaact attcatcctg aaactttgtc aatattaaga acttacttac aatataaaga
    10921 ttgtgagata gtagaaattg acttttgtaa tgaatatggc actacagata tagaaaaatt
    10981 aaaagcttct gtagacaaag atacagcatg tgttcttata caaactccta atttctttgg
    11041 aattattgaa gaaatggaag aaatagaaaa gataactcat gaaaataagg ctatgttaat
    11101 tatgagtgta gacccaatat cattaggagt tttaaaaaca ccaggtgaga taggtgcaga
    11161 tattgttgtt ggagaagctc aatcacttgg aaaccctctt aattttggag gtccttatgt
    11221 aggattttta gctagcaaat ctaaatatac tagaaaaatg ccaggaagaa tagttgggca
    11281 aagtttagat gtagaaggta aaattgcata tgtattaact ttacaaacta gagaacagca
    11341 tgtaagaaga gaaaaagcaa cttctaatat atgttcaaat caagctttaa atgctcttgt
    11401 agcttcaata tatatagcta ctatgggtaa agaaggattt aaagaggttg gtatgcagtc
    11461 tatgaaaaaa gcacattata cttacaataa gcttgtacaa actggaaaat ataagccaat
    11521 atttaaaggt aagtttttca aagaatttgc tgtacaagga aatcttaata tagaaactat
    11581 aaatgataaa ctcttagaag aaaatatatt aggtggttat aatttagaat acaattatcc
    11641 agaattaaaa aattcaactt tgctttgtgt gactgagaaa agaagcaaag aggaaataga
    11701 taagttagtt ggaataatgg agggattata atgaaagaat acaatagttt gttgatagat
    11761 atatctaaaa aaggtaggaa agcatactca cttccaaagt tagatataga tgatataaaa
    11821 atagaaaata tgattgacca agatatggca agacaaagtg agttgaattt gccagaagtt
    11881 ggtgaattag aattagttag acattataca ttattatcaa ataaaaactt tggagttgat
    11941 acaggttttt atcctttggg ttcttgtact atgaaatata atcctaaaat aaatgaagat
    12001 atggcagcac ttccaaactt tactggaatg catccatacc aatcttcgga tacagctcaa
    12061 ggttctcttt ctttgatgta tgatttatca agaagacttg cagaaattac aggtatggat
    12121 gaagttacac tacaaccttc agcaggttct catggtgagt ttacagggct tatgattata
    12181 aaagcatatc atgaaaatag aggtgaccat aagagaacca aagtgataat tccagattct
    12241 gcacatggaa caaatccagc aagtgcagct atggcaaact ttgatgtgat tcaaatagca
    12301 tctgataaaa atggagctgt agacataaat gcattaaaag aggttttgaa tgatgaagta
    12361 gcagctctta tgcttactaa tccaagtact cttggtttat ttgaaaaaaa tataaaagaa
    12421 atagctactc ttgtacatga agcaggagga cttttgtact atgatggtgc aaacatgaac
    12481 gctattatgg ggataacaag acctggagat atggggtttg atgtggttca tcttaatctt
    12541 cataagactt tttcaactcc tcatggaggt ggaggtccag gagctggtcc tgttggagtt
    12601 aaaaaagaat tagtaccttt tttaccaata ccagtaattg aaagaaaaga agataagtat
    12661 gtactaaatt atgatagaga aaaatctatt gggaaaatta aaaatttcta tggtaatttt
    12721 ggagttcttg taagagctta cacatatata ctaactatgg gaagggatgg acttaaagag
    12781 gctagtgaaa tggcagtttt aaatgctaat tatataaagg aaagtataaa agatgattat
    12841 attttgccaa tagatacctt gtgtaagcat gagtttgtat taggtggatt gccaagagga
    12901 gaggccaata taaaaactat cgatattgca aaaagactac tagattatgg ataccatcct
    12961 ccaacaatgt actttcctct tattataaat gaggcactta tgatagaacc tacagaaagt
    13021 gagagtatag agacattaga tagttttata gaagctatga aaagtgttgc taaagaggca
    13081 aaggaagaac cagaactatt gaaaactgct ccacataata ctttggtcaa aagagtagat
    13141 gatgcaaggg cagtaaagaa acctatacta acatggtcac aaagataaat agttaaaaag
    13201 tagagattta aagtataaag agaattaaat ttgtaagaaa aagctatcta acttaatcta
    13261 gtttagatag cttttttgta tattagtatg tatggtattt tctatataaa gttttaaatt
    13321 atattagtgc ttatatagaa tattgatatg atgattatgt atagatatta ataagaattg
    13381 ttgaatttat cttgccttaa ctttatttac tcttttatat taagaaaaac ttaactaaaa
    13441 tatagcgaaa ttcataaaaa tttaggaaat cttaagaatt ataata
//
LOCUS       DAEPXW010000099        13172 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.101, whole genome shotgun sequence.
ACCESSION   DAEPXW010000099 DAEPXW010000000
VERSION     DAEPXW010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13172
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.101"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..626
                     /locus_tag="KRM55_002967"
     CDS             <1..626
                     /locus_tag="KRM55_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595181.1"
                     /translation="KKSKNKIIFPTGLFSKVVVISDDLYNEVKGEFSKINFHGFDYKN
                     WQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQFMGVFIGVILFIA
                     VFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLFFIPYFIAIINSII
                     SLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWFFD"
     gene            745..2136
                     /locus_tag="KRM55_002968"
     CDS             745..2136
                     /locus_tag="KRM55_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1595182.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            2243..3283
                     /locus_tag="KRM55_002969"
     CDS             2243..3283
                     /locus_tag="KRM55_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1595183.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            3772..4425
                     /locus_tag="KRM55_002970"
     CDS             3772..4425
                     /locus_tag="KRM55_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1595184.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            4501..4710
                     /locus_tag="KRM55_002971"
     CDS             4501..4710
                     /locus_tag="KRM55_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595185.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(4850..5416)
                     /locus_tag="KRM55_002972"
     CDS             complement(4850..5416)
                     /locus_tag="KRM55_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBH1595186.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            5577..6230
                     /locus_tag="KRM55_002973"
     CDS             5577..6230
                     /locus_tag="KRM55_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBH1595187.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(6388..6564)
                     /locus_tag="KRM55_002974"
     CDS             complement(6388..6564)
                     /locus_tag="KRM55_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595188.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
     gene            7092..8036
                     /locus_tag="KRM55_002975"
     CDS             7092..8036
                     /locus_tag="KRM55_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBH1595189.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            8058..8684
                     /locus_tag="KRM55_002976"
     CDS             8058..8684
                     /locus_tag="KRM55_002976"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBH1595190.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            8718..9767
                     /gene="hisC"
                     /locus_tag="KRM55_002977"
     CDS             8718..9767
                     /gene="hisC"
                     /locus_tag="KRM55_002977"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH1595191.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            9770..10348
                     /gene="hisB"
                     /locus_tag="KRM55_002978"
     CDS             9770..10348
                     /gene="hisB"
                     /locus_tag="KRM55_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBH1595192.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            10350..10955
                     /gene="hisH"
                     /locus_tag="KRM55_002979"
     CDS             10350..10955
                     /gene="hisH"
                     /locus_tag="KRM55_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBH1595193.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            10952..11674
                     /gene="hisA"
                     /locus_tag="KRM55_002980"
     CDS             10952..11674
                     /gene="hisA"
                     /locus_tag="KRM55_002980"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBH1595194.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            11656..12414
                     /gene="hisF"
                     /locus_tag="KRM55_002981"
     CDS             11656..12414
                     /gene="hisF"
                     /locus_tag="KRM55_002981"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBH1595195.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            12442..13110
                     /locus_tag="KRM55_002982"
     CDS             12442..13110
                     /locus_tag="KRM55_002982"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBH1595196.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         5248 a         1236 c         2314 g         4374 t
ORIGIN      
        1 taaaaaaatc aaaaaataaa ataatttttc ctacaggact gtttagtaaa gttgtagtta
       61 taagtgatga cttatacaat gaagtaaaag gtgaattttc aaaaattaat tttcatggat
      121 ttgattataa aaactggcaa agcagtgcaa agataactga aaatttaaaa gaaaaacatt
      181 ttaatttgga tagagaatat aacaggtcat attttttaac attaccagat atgtatttag
      241 tagagttaca acaaagtaaa attcttcaat ttatgggtgt ttttatagga gtgatattat
      301 ttatagcagt ttttagtttt ttatacttca gattatatac agacgagata gaagataatg
      361 taaagtacaa aaaactatca aaaataggtc tatcttttaa aaatatgaat aagattgtta
      421 gtatagagat aggtacattg ttttttatac cgtattttat agcaattata aatagcataa
      481 tttctttact gtttttaaat caagtattaa ataatagttt taagttagaa aatttgggta
      541 tattactact gatatcatct atatattcac tttattttta cttattaaaa aaaatttata
      601 ctagaaaagt ttggtttttt gattaaagtg gtatataata gatatataaa ttaatattta
      661 aaaagtagtt aatattaggg gagggcattt gcacctccct tgtaatatgt ggaaaattga
      721 atattagaag aaggaggaga cttgatggaa aatcaacaat tattaggaac agaacgaatt
      781 agtaaattac tactaaaata ttctatacca gctataatag gtatgttggt aaatagttta
      841 tataatgtag tagatagaat ttttattgga aatataccag gggttggacc acttgcaata
      901 acaggtcttg gtgtaacaat gccaataatg acaataatac ttgcatttgg gatgttgata
      961 ggtataggaa ctactactac catatcaata aaacttgggc aaggtaaagt agaagaggca
     1021 agaaaactta taggaaatgc aatgacgtta tctgtaataa caggaattat cataatgata
     1081 cttggaatat tatttgcaaa taaaatactt acattgtttg gagcaagtga aaatacttta
     1141 atatatgcaa aatcatatat caatattata ttattaggta cagtagtaaa tcttctttcc
     1201 ttttctttaa accactcaat aagagctgat ggtagtccta aaatttcagc aggaataatg
     1261 atagtaggat gtttaactaa tatagtttta gactggatat taatatttgg attcaatttg
     1321 ggaatacaag gagctgcaat tgctacagta acttctcagg ctcttacagc tattttaact
     1381 atagggtatt atataagtgg aaaatcaaac ttacgattca gtaaatctaa tctaaaatta
     1441 gataaaaagc taataaaagc agtgtttgca ataggtatgt cgccatttgc tatgcaactt
     1501 gcagcaagtt tagttcaagt aatatcaaat attgcactta aaactcatgg tggagattta
     1561 gctatagggg ctatggctac tatttcttct attgcaatgg tatttttgat gcctatcttt
     1621 ggaataaatc aaggagcgca acctattata ggtttcaatt atggagctga aaaatatgat
     1681 agggttaaaa aagcatattt aggttcatta gtagtagcta ctataatttt atgtatgggt
     1741 atggtagtag ttatgctttt cccagaagct attataggta tatttaataa agaccctgaa
     1801 cttatgaata tatctgttaa tggattaaga atatacttac ttatgttgcc aattgtaggc
     1861 ttatcagtta caggaacaaa ctttatacaa tctataggaa aagcaaaaat ggctatgtta
     1921 ttgagccttt taagacaagt aattttattg ataccagcag tattaattct tcctacattc
     1981 ttaggtttac agggtgtatg gacagctcaa ccagtgtctg attttatagc tacagtaatt
     2041 acaggtatag ttgtatttag agaattaaaa agatatactc ctaaaactga aaaattaaat
     2101 gaaaatgaaa gactaaacga gataactact gagtaaaaat ataaattcag ataattgagc
     2161 aagaaattgc aaaaaatacg attatatgat aaaataaaac cgctgtcaag gataagagaa
     2221 attctaatta tggagtgatt ttatggaatt tacaaagaaa agcaaattaa aaaatatgta
     2281 tgtaaacatg aatgtagcta gaatgttgtc taagataaat gagtataagg gtagacaact
     2341 gctttacaaa aaacaaccaa aagaaatttt agaaaactta gaaaaaaaat ctttagtaga
     2401 ttgttctgaa tctacataca ttggaaatca aagagatagt agtaatttta atctagaaaa
     2461 gttgataagt aatgaagtta cacctagaag tagagaggaa ttgagtattg ttgaatacag
     2521 agatgtggta aaaactatta acagtgctta tgagagtatt cccatcagtt cacaaacgat
     2581 tcttgagctt catggatact tatataaatt ttcatctact agaggaggaa gttataagtc
     2641 agataatgat tttattgaac acaatttaaa acctagcgaa tttataagta ctgattcaag
     2701 tgtcaataaa gttgaaaaag ctgtagaaga aatatgtgaa gcttataata cattgataga
     2761 ggaagatgaa attgatatat taatattaat ttctgcattt gtgttagatt tcatattgat
     2821 acatccattc aaagaaggta atataaaaat ggcgagagta cttatcctat tgttactaaa
     2881 taaaaatggg tatgaagttg gaagatatat aagtttagga aagatatttg atgatagttc
     2941 atatgaatat tatagtaatt taaattattt gaaagcctca ataggtagtg aaaaagcaga
     3001 tatgaatgca tggattgagt attttttaga gacgatatta actgcatatg agaagctgga
     3061 tgatagttta aatatatctg ataagaaaag acaaacaaaa actagtagaa tagagaaaat
     3121 aataaattct acccttggat attttacaaa agaagatata agagatttat gtcctgacat
     3181 tccagaacct actataaata gagtttttaa taatctaaga aaacaagata agatagaagt
     3241 tgttgcaaga ggaagaagtg caaaatggaa gaaaaaatat taaaaaatgt ttagataact
     3301 aaaatggtat agtgttttac actataccat ttttaatgtc attagcatga gcaataattt
     3361 aacaacttaa gcaatatcaa ttttatttat tgattatttt tgaactgaaa aatggcgtta
     3421 tatggtatac ctcagtggta attaattttg gatgagaaga tataatatta cagaatatat
     3481 taggagtata tgtagaaaaa atataataaa agtgtgaggc ttagtaatta acaaattatg
     3541 tggcttcaca cttttttata aaataaagat acttagcaga ataatatttt agttgatatg
     3601 tttataagat ggtacttgtt tgggtaaaag tataaatagt aaaaaagtag aagtaatgtg
     3661 tataaaaaca taagttacat tctgtaataa tagttatttt ataattcaac aaaagaatag
     3721 aatgggtata tttgtgaaat aataatataa aataatctta ggagtgagct tatgaagaaa
     3781 aaattattat atataaatgt aaattcaaaa cctgaagact tatcttcaag taaaactgta
     3841 gcaagaaaat ttataaataa atttatggaa aaaaacaaag attttgaggt tgaagagata
     3901 gacctttata aagaacatat accaagactt gagtatcagt actttgaaaa aagaaatagc
     3961 atagttagtg aagaaaatgc taaaaattta gacgataagg atagaaaaga gcttacaaag
     4021 attagaaatc tttgtgacca atttgtgagt gcaagtgtat atgtaatagc agcacctatg
     4081 tggagtttat cttttccagc accacttaaa gagtatatag attgtataat tcaagatgga
     4141 aaaactatat cttttgaagg caatgataaa ccacaaggaa ttttaaatga tattgataga
     4201 agtatggtat atatacaatc ttctggtgga cacataccat gggtgttgaa gccagttatg
     4261 aataaagggt taaattatgt ggaaagtatt atgaaattta taggaattaa aaaatttgat
     4321 gaattgttag tagatggaac tggaactagt gaagaagaaa gacaagctgc aatagaaaaa
     4381 gcatctgaaa aaatagatgg tataatagat gggatgaaat tttaattata atattttatt
     4441 aaaaatataa aggaaaaacc tcttttaatg tagaaactta tattgaagga ggcgagaatc
     4501 atgcgagaag aaaaaagtaa tgaaaagtat gattgttatt ggtgtaatca agagaataat
     4561 ttctgtgtag aaataaaaga taatatagtc atgatagatg atggcactgg tacgttaaaa
     4621 caagccgttt tcatagggta taaacaaatc caaattaatt taaattgttc acattgtcaa
     4681 aacttaaata gaataaaatt aaatttgtag aattttaaaa tggaaattat tgaaggaatt
     4741 aaaaatagaa agtgttaata tttagactga aaattatatt ttatacaata aaagtttatt
     4801 taaataacat tgtattttaa tatttatttt cagtcttact ttattaaaat tattttttgg
     4861 ttatgtctgg aaaatatctg tctactaatt tttctgaaat attttttaat tggtcagcca
     4921 ttgaagtcag acttaataag gctatcaata aatcatcttt attttctgga tttatactaa
     4981 tattttcaaa attagactct ataaagtccg gtatattctt tctttgattt tcttttatta
     5041 acatgaattt ttcgtaacat gaaactaaat ctttttcact gaaattatcc ttttcataca
     5101 caccatgtaa gattctttta atttcttgta ttgtaagtgt atttttcata gaataaataa
     5161 ttatcatctg taaaatttgt tctttagtat acttttttcc cttaactggt ttgattaatc
     5221 cctctttgct gtaattattt atcatggttt tagtaagaat tttatcactt tcaaatcttt
     5281 tattagcaga aagcttattg tcaattagag aaataatttg atccatatat aagtcaatag
     5341 atggaatatc gtttgaagtt atatctgcat tatttagtgt ttctagtatt atagtattaa
     5401 gttcattatt catcatatgt tacctccata atatatataa tacactaaat tagaaagtaa
     5461 aacaatatta aggcttgtaa aaaaaacata aagtggtata attaaatata taatatagta
     5521 atggaaacta tatttatgaa tctgattttt aaaatacata attgtaggag gacgaaatgt
     5581 atcaattttt tttaaagggt agagacccaa taagcagttt aactcatttt ataggtgctt
     5641 gtttatctct tttagcaact ataattttag tttttcaatc tgttacatta caggaaactt
     5701 ctctcttgat gatagtatct gtatcggtat ttggactttc actaattgct ttatatagtg
     5761 caagttcgta ttatcatttt ttaaagggga caccagaaca agaattgttt tttagaaaag
     5821 tagaccatgc aatgatttac gtattgattg ctggctctta tacaccaata tgtctgaatt
     5881 ttatggaaaa aaaagaaggc ataatatttg ttacagcaat atggatagtt gcatttattg
     5941 gtataataat aaaaatattt tggatggatg cacctagatg gttatctacc agtatatatt
     6001 tacttatggg atgggcaatt gtttttgata taaatgcatt caattcaatt cctaaggatt
     6061 gccttagact attaattatg gaaggtgtat cttactctat aggtgcaatt atttatataa
     6121 ttaaaaagcc taatataagt cctgagtttg gatttcatga aatattccat atttttatta
     6181 tgataggttc tttatttcac tttttagcag ttttattgta tgttttatag ttttaaaaga
     6241 tttgattaat tgatactaaa attctacaat gaataaaatg gaactgcctt atatagatta
     6301 tatcttcgac aataagacag ttccttatta taaatattaa attctactta taataaaatt
     6361 ttgataaaaa tagtccattc aaaatgccta ttccataatt cctttaatgt acttttcatt
     6421 tacgacatat agtttgaatt tatgtactat aattatatcc tctaaattct ctgaaacact
     6481 aacaattctg acacatttgt ttctaatttc tacaggtaaa tctaaatcat ttgttaaatt
     6541 cacatagtca tcatatttat acataaaatc atccctttac attaagatat acttattata
     6601 ctatatttta ataagttttt ttaaattatt acaatttttc ccgaaatttc attttttata
     6661 cataaaattt ccaaattagg taaagattaa attttttatt gtataaacaa aagttacata
     6721 taaaatattt tattcaattt tttaaataac tattgccaat ttttgaaaaa tatattatta
     6781 ttaatagtaa caaaaaactg taaatttaga atattaataa aaattatttg ggaggaaatt
     6841 atcatggtga gattaaatat agtaaaatta aatacaaaat taaatcatca ccatcatcat
     6901 agattaaagg gattgtaata tgaaattaat tcatagacac aagccctgtt tttagtgtaa
     6961 ttggtcttgt atctatgatg ggaagtaatt ttaagagaaa attatagcca tataggtata
     7021 aagcctatat ggctttttta ttgttttaaa tttgcaaata taagagtaaa tttaatgaag
     7081 agggtgagaa tgtgaaattt ttgaggattg aagatgaggt tatttattct aaaaaaagat
     7141 ataaattaaa aagggaaata gataaacttt ttttggatga agaatatttt caaatagaac
     7201 cacaattatt tgaagaatat gatgaattta caactataaa taataaaatt ccagaagaat
     7261 ctatggtaaa ggttgtaaat ggaaaagtaa tggtacttag agctgatata actacaagta
     7321 taataaaaag ccttgtacca agatgggaag atggtttaaa gcttaagctt ttttataatt
     7381 catcaatata taaaaataaa aatacagttg gaataaaaga gataagacaa ataggttgtg
     7441 agtatctagg agaagcctct gtagaagcag atagagaagt agtgaaatta gctcttaaga
     7501 tacttgaaaa atacaataat aattttattc tagaggttgg gagtagcaag tatattcatg
     7561 gtttgttaga agaattaaat ttaaataaga attgtgaaaa tcaaattaaa aatttactat
     7621 atacgaagaa cactcatgaa ttaaaagtat atattgaaga attaaaaatt aagcgtgaag
     7681 taaaagagtt attatcaaat attttaagtt tacaagggaa tttatataat gttattgaaa
     7741 aatcaaacaa gttctattgt aataataaga tgaagcaagc tcttgaagaa ttaaagcaag
     7801 taaataattt gattgaggaa tgtaattttt tagataaggc tagatttgat ttatcaatga
     7861 ttactatgct tgactattat gaaggaatta tgtttagagg atactaccca aactcatata
     7921 aagaaattct tagtggtgga agatatgatt ctttaactaa agagtatgga aaagaaattc
     7981 cagccattgg atttacacta agtgttgatg agttaatgaa gtatgtatat aagtaaagtt
     8041 tagaaggagg gattgctttg gattatttga ctatagcact agcaaaagga cgaattgaag
     8101 gggaatcatt taaaaaattt aaaaaaatgg gtctaggaga tagtatagac acagatacga
     8161 gaaaactaat ttttaaagat gaagaaaata aaattatata tatacatgta aagccatcag
     8221 atgtagttac atatgttgaa aaaggagtcg ctgacctcgg tatagcaggt aaagatacta
     8281 ttttagagaa tgagacagat gtatatgaaa tatatgattt aggttttgga aaatgtaaat
     8341 ttgctgtagc aggattaaag ggagatagca tatatagaga agatgaatat ttaaaagtgg
     8401 caacaaagta tcccaatata gcaaaaaagt attttaaaga gaaaggtcaa aaaattgaaa
     8461 taataaaatt aaatggttct gtagaactag ctccaatagt agggttgtca gatgtaattg
     8521 tagatatagt tgagactggc aatacactta aagcaaatgg tcttgaaata ttagaagaca
     8581 tatgtaatat aagtgctaga attatatcaa atagagctag ctatagattt aaatatgaac
     8641 aaattcagaa tataattcgt ttatttgaag aacttgataa ttaaaatata attgagcttt
     8701 ataaggaggg atttaagttg agagaaaaag aaagcataag agagttaagg ggatatgaac
     8761 caaatcacgt aaactgtaaa gtaaaacttg atgcaaatga aggaagtaag aggttgttta
     8821 aataccttat taaagaaatt tcagatagtg atatagattt aaatttatat cctgaagatt
     8881 cttatagtga tttgaaagaa tctataatag attacataaa tatttctgga gtaaataaga
     8941 aaaatcttct agtaggaaac ggttcaagtg aaataattga tttaataata catacttttg
     9001 tagataaaga tgaagtaata ttgagtttct ctccaagttt tagtatgtat tctatatata
     9061 gtcagataaa tgggtctaaa tttataggtg ttgaaagtga tgaaaattta gttataaata
     9121 tagataatgt gattgaaaaa gtaaaggaga ataatcctaa aatagtaatt gtatgtaacc
     9181 ctaataatcc aactggaaca atattaaaga gggaagagat aataaagctt ttagattcaa
     9241 ctaatagtct agtggtttta gatgaagcat atatggattt tggagaagaa agcatgttaa
     9301 gtgatgtttt taagtatgat aatctaatag ttcttagaac tttatcaaag gcatttggat
     9361 tggctggaat aagaacagga tatatgttat ctaatagtag tttaataaat tctgttgaga
     9421 aagtaagacc tccatataat ttaaattcat tatcagactt tattgctaca agagcactta
     9481 gaaataaaga tgtggtaaag gcttatataa aggaagtaaa agaggaaaga gaagttttat
     9541 atgaagaaat gattggtatg ggaattaaag catacaaatc acaagcaaat tttatattat
     9601 tttattctga aatcgaaaat ttatcacaaa aacttattga tagaggagtt ttaataagaa
     9661 aatttggtgg aaagttagaa aattattaca gagttacaat tggtgataaa gaagaaaatt
     9721 ctatgtttgt tggagctata agagatattt tgaaaaagga gaaataggta tgagaatttg
     9781 gaaggtagaa agaaatactc ttgaaacaca gattttagta gaattaaata ttgatggttc
     9841 tggtaaagct gaaatagata ctggaatagg atttttagac catatgctta ccttaatgtc
     9901 atttcatggc aagttcgatt taaaagtgat ttgtaagggt gatacatatg tagatgacca
     9961 ccatagtgta gaagatatag gtatagctat aggtgaagca tttaaaaatg ctctaggtga
    10021 caaaaaagga atacgaagat attctaatat ctatatacct atggatgaat ctctatcaat
    10081 ggtagcaata gatataagca atagacctta tcttgtattt aatgctaaat ttgataccca
    10141 aatgattggt agtatgagta ctcaatgctt taaagaattt tttagagctt ttgtaaatga
    10201 atcgagagta acattacata tcaatctctt atatggggaa aatgaccatc ataagataga
    10261 aagtattttt aaagcatttg caagagcttt aaaagagggt agtgaaatag tttctaatga
    10321 gatagcatct tcaaaggggg ttttgtagaa tgaatataat agtagactat ggtcttggaa
    10381 atatagattc tgtgtctagg ggttttagaa aagctggaat agaaactaaa atttctagtg
    10441 atatagatga aataaaacag gcagattcac ttatacttcc aggtgttgga gcttttagag
    10501 attctataag tgccttagat aaactaggat tgataccaat aataaaggag catgtttcta
    10561 agggtaaatt tatgataggt atatgtctag gaatgcaatt actttatgaa aaaagttatg
    10621 agtatggaga atatgaagga ttaggactta taaaaggaag tattgataaa ctggatataa
    10681 gtttaaaagt gccacatatg ggatggaata atctaaaatt taataaggca aatgatgata
    10741 tacttaaata tataaatgaa gatgattatg tatacttcgt tcactcatat tatgcaaatt
    10801 catcaaatga agaactaatt gcattttcag aatatgaaaa gaaaatccct gctattgtta
    10861 gaaaaggcaa tgtatatggt atacaatttc atcctgaaaa aagtggagaa gtagggttaa
    10921 atatattaag agcatatggg gagatgataa aatgataata tttccagcaa tagatataaa
    10981 agataataag tgtgtaagac tcacacaagg agaatttgac aaagtaaatg tatattatga
    11041 taatccatta gaagtagcat ataaatggaa aaatgaagga gcagaatata tacatatagt
    11101 agatttaaat ggtgctagaa gtgaatttgg tgtaaataca aaaataattg aggacatagc
    11161 aaacaatata gatataccta ttcaagttgg cggtggagtt agggataagg aaaaagtcaa
    11221 aagtttaata aatgctggtg ttactagagt aatattaggc agtatagcga ttgaaaattt
    11281 gaatttagtt gaagaattgg tcaatgaata taaagagaaa attgtagttt ctatagatgc
    11341 taaagatgga aaagtagcag ttaggggatg ggaagttgta agcaatgtag actcattaac
    11401 attatgtaaa caacttgaaa agataggtgt acaaactatt gtttatacag atatatcaaa
    11461 agatgggatg ttgcaaggtc caaattttga catatatgaa agaatagcaa aggaaacatc
    11521 actaaatgtt attgcttctg gaggcgtaac ttctatagaa gacgtaaaaa gactaaaagc
    11581 tatgaactta tatggtgcaa taataggtaa agcgctttat gataaaaaga tagactttaa
    11641 ggaggcacaa caattatgct tactaggaga ataatacctt gtctagatgt gagaaatgga
    11701 agagttgtaa aggggaaaaa atttaaagat atagtagatg ttgatagtcc agaagtactt
    11761 ggaaaatttt atagtgattg tggtgcagat gaacttgtat tctatgatat aactgcatca
    11821 aatgaagaga gaaagacatc tttagaattt gtgacaaaag ttgcagaaaa tataaatata
    11881 ccattttgtg ttggtggagg agtaaataaa ttagaagatt tcactgatat tttaagaaaa
    11941 ggtgctgata aagtttctat aaattcatca gcagtcaaaa atcctgaatt aataagggaa
    12001 gcttcattaa aatttggagc acaatgtgtt gttttatcga tagatgcaaa gaaaaatgaa
    12061 gagggttcat ggagcgtata cgtaaaaggt ggaagagaaa aaactaatct ggatgcaatt
    12121 gaatgggctg ttaaaggtgt agaacttgga gcaggagaaa tcgttgtaaa tagtatggat
    12181 gaagatggaa tgaaaaatgg atatgatata gaattattat caaagataac ttctttagta
    12241 aatgtacctg ttatagcatc tggaggcgct ggaaaaaagg aagattttta tgaggcggtt
    12301 aataaatcca atgtagatgg aattttagca gcatctgttt ttcattttgg cgagataaaa
    12361 ataaacgatt taaagaaata tttaaaagac atgggtgtag aagtaagatt ataagttaaa
    12421 tactaaaagg agattagaaa tatggataat aagtgtaaca atgtatacag tgatgaagta
    12481 gagaaattta taagaagtat aaagtttgat gataaagggt tagtccctgt tgttgttcaa
    12541 gaggtagtta gcaaagatgt actgatgtta gcatatatga ataaagatgc tataaagaaa
    12601 accttaaaag ataaagtagc ttgctatttt agtagaagta gacaagaact ttgggttaaa
    12661 ggtgagacat ctggtaatac tcaaaaagta gttaagatgt cttatgattg tgatgtagat
    12721 actatactac tttttgttga acaaactggt gtagcttgtc atacaggcaa ttattcttgt
    12781 ttttacagag acttgtttga tgatagttca aaaatggagc ttgaagtaca aacaaatata
    12841 ttgaaagaat tatatgattt aatcaatgaa agaaaaaata atccagttga aggttcttat
    12901 actaattatc tttttgaaaa aggaatagat aagattctta aaaaagtagg tgaagagagt
    12961 agtgaggtaa ttatagcatc aaaaaatacc gataaaagtg aacttattta cgaaattagc
    13021 gatttagtat atcatacatt ggttttaatg atagaaaaag gtgttgaaat tgatgaaata
    13081 aaaaaagaat tacttaaaag aagaaaatag aataagatag attaatgggt aataagaaaa
    13141 tataccgctt ttaataaaaa gtggtatatt tt
//
LOCUS       DAEPXW010000100        13155 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.102, whole genome shotgun sequence.
ACCESSION   DAEPXW010000100 DAEPXW010000000
VERSION     DAEPXW010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13155
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.102"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            845..2515
                     /locus_tag="KRM55_002983"
     CDS             845..2515
                     /locus_tag="KRM55_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBH1595197.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESSKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2637..3371)
                     /gene="pflA"
                     /locus_tag="KRM55_002984"
     CDS             complement(2637..3371)
                     /gene="pflA"
                     /locus_tag="KRM55_002984"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBH1595198.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWENLGIDYELKD
                     VPDATKEDIQKASEIISKFGVKVYNS"
     gene            complement(3531..5762)
                     /gene="pflB"
                     /locus_tag="KRM55_002985"
     CDS             complement(3531..5762)
                     /gene="pflB"
                     /locus_tag="KRM55_002985"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBH1595199.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPGALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            6055..7116
                     /locus_tag="KRM55_002986"
     CDS             6055..7116
                     /locus_tag="KRM55_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBH1595200.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            7207..8820
                     /locus_tag="KRM55_002987"
     CDS             7207..8820
                     /locus_tag="KRM55_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1595201.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            9151..11505
                     /locus_tag="KRM55_002988"
     CDS             9151..11505
                     /locus_tag="KRM55_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1595202.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMALHKVNYISDELD
                     TTSNKVNYVSDELDMALHKVNCVSDELDMALHKVNCVSDELDMTSNKVNYVSDELDMT
                     SNKVNYVLDELDITSNKTDYISNELYNLSNKSIKDNIPIKMAVITKSNMLNQLPDLVE
                     LERVFSKIEFKVCFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVK
                     PAHKLMDEYYFFMELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFT
                     IHNPVAWEDKKFETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNH
                     HADTLFSQHFMDKKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGN
                     YIVKMYVGWWKKHGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            11593..11928
                     /gene="spoIIAA"
                     /locus_tag="KRM55_002989"
     CDS             11593..11928
                     /gene="spoIIAA"
                     /locus_tag="KRM55_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBH1595203.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            11942..12370
                     /locus_tag="KRM55_002990"
     CDS             11942..12370
                     /locus_tag="KRM55_002990"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBH1595204.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            12393..>13155
                     /gene="sigF"
                     /locus_tag="KRM55_002991"
     CDS             12393..>13155
                     /gene="sigF"
                     /locus_tag="KRM55_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBH1595205.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
BASE COUNT         5080 a         1571 c         2171 g         4333 t
ORIGIN      
        1 aatggaaact atggatgtaa taattaaaat aaaaaatatt attttatatt tataaacatt
       61 gacattctaa ttttgtagtg taatcgtatt ttttattaat tcttacaaaa tcaatgaaaa
      121 taagtatatc cattttaaag tacataaatt taaaaatcca gaaaaatata cttaaattat
      181 gtaagtaaaa gaggggttga atcagttgaa aatgtaatat tagtaaatag tacatcaatc
      241 ctatataccc tgtaagcaac tctattttca tgtactaaaa atgtacctat tttattaact
      301 gaaaagaata aattaaatgt aagtacataa gaagatagaa aaaattaaaa acaaaaaata
      361 tttatataaa taaatataaa aaatgatata atccctatta aaaaatttat agatgatgaa
      421 gaaatatcaa aatcttatat tataggaaga gacacttctt tgccaaaatc tatagaaaag
      481 caataccaaa tccaaagaga ataggcgaag aaaaaaataa aataaattca agagtaatag
      541 aaaagtttta tagaataaag aactgataac tctttatata acgaaaaata gaattttaag
      601 agaaaatgat ttaataaatg atttaacatg gtgttttagc aggtaaaaat aaatcaccag
      661 taatgattat agaaaaatta ctttatgaat ctcaaaaaac ttagttaaga gtaagagatt
      721 tgataagata actaaagttg gggaaatgtg tttgatgaga caaaaaatta gtaaaatagt
      781 ataatctaaa taaggatatt ttgttgatta aactacacta atagtaatat tgtaggggga
      841 aaagatgaga gaagaatcga actctttaag tttagaccat atagaaattt tctttgaact
      901 tttatctcaa agtacagaag attatatatt tttttgggat ataaatagga ataaatttaa
      961 aatttcttca gcaatttttg atgaatttaa cttaagtaaa gagatagaat ctgatttggt
     1021 caattgttgg agtaaaattg tttatccaga tgatgttcaa atatggaaag atgatataca
     1081 agaattacta catggaaaaa aaggtgagca caatttagaa tataggttga ttaataaata
     1141 taaagaaata gtatggattt cttgtagagg taaagtttat gtgtcggatg acccaaaaac
     1201 tatatttcta gtcgggagaa taaagaatat tggtgaaaaa aataaatttg attctatcac
     1261 aggaacgtgg aatagagaac aatttgaaca tagaatgaat tatcttataa aagagaaaat
     1321 ttataaaaat ggtgctatgt ttattatgga tattgataat tttaaaaata taaatgaaaa
     1381 atatgggcat tcttatggtg acaaagtatt gcgtgcaatt gctactgaag tattagaata
     1441 tcttccaaaa gatgtaagat tgtataggtt agatggagat gaatttgcat ttttttaccc
     1501 tatgtgtact aaagaaacta tagagaaaat atatgaaaag atacagatgt atacaaatac
     1561 tcagcatgaa attgaatcaa gtaagtacta ttgcacagtg actgcaggcg ttgctatgta
     1621 tccagaagat ggagataatt atttagattt atttaaacat gctgatattg cattggatat
     1681 agcaaaaatt agtggtaaaa atagaattaa gtttttttca caagagctct atgaaaataa
     1741 actaaaggta atttcaatgc aacaaaaact aagagagtgc gttgaaaata attttaatga
     1801 ttttgagttg ttttttcaac cccaggtaaa tgctgttaca aaagaggtaa taggggcaga
     1861 ggtactttta agatggcatt cgagtactta tggagaagta tctcctgttg aatttatacc
     1921 aatactagaa cagagtaatt taattatacc agttgggaag tggattataa aagaagctgt
     1981 aaaacagtgt aaagaatggc ataaaataaa tccagacttt aaaatatctg taaatgtatc
     2041 gtatattcag ttaaaggaag atttttttag agattttata gtagaatgtt tagtagagta
     2101 tcaattaaga cctgaatttt taattttgga attaacagag aattgttgga taccagatat
     2161 aaatttacta aatgataaat ttattagttt aaagggtata ggagtatata ttgcaataga
     2221 tgactttggt acaggatatt catctttaaa ttaccttaaa gaactgtctg ttaatataat
     2281 aaaaattgaa agaagttttg ttaagaatat tacatataat agttatgaat atacttttct
     2341 tgaatatatt attaaattag ctcatattat aaatttaaaa gtttgtgttg agggaataga
     2401 gtcttatgaa gagtatgata tagtaaaaag cttaggtgta gatattattc agggtttttt
     2461 atttggaaga cctgtaagtg cctctgaatt ttataaattt caactatcaa agtgatgtat
     2521 ataaaatgag atatatagta tataaaaata gggcaaagtg gaagttttga agtttattaa
     2581 aaatttacac tttaccctat tttgttatgt cttctataaa ggattaatat actacactaa
     2641 ctattatata ctttcactcc aaatttagag attatttcac tagctttttg gatatcttct
     2701 ttagtggcat caggaacatc ttttagttca taatcgatac ctaaattttc ccatttgtgt
     2761 attcccatag aatggtatgg tagtaattca aatctttcta catttttcaa tgtagctaca
     2821 aattgaccta gtttttctaa attatctata tcatcagtaa tgccaggaac taaaacatgt
     2881 cttatccata caggaatatt tcttgattct aagtgtctag caagttttaa tgccttgtcc
     2941 ataccaacac cagtcaaatc aatagatttt tcctcaacca tatgttttaa atcaagtaaa
     3001 accaaatcag tattatctaa aactgggtct atagtttcta tatctacaaa tccagatgta
     3061 tccaagcaag tgtgtatatc attttctttt gcttttttaa ataattcact taaaaattct
     3121 ggttgaagag tggattcacc accagaggca gttatacctc caccagaaaa cttcataaaa
     3181 gaagtatact taagagcatc cgttattatt tcatcaactg tgtattcttt tcctgattta
     3241 atatcccatg tatccctgtt atgacagtat ttgcatctaa gaggacaccc ctgaaaaaat
     3301 aatatatatc ttattcctgg tccatctaca gtaccaaacg tttctataga atgtatcttt
     3361 cccttaatca tagagttcac ctcacaatat attttaataa ccttatcaat agttataata
     3421 tttctctaaa aaaggccatc ttataccaga aataattcaa atataagata gccttttatt
     3481 tttatttttt acacagtagt aatcttagtt aaagtataaa aatttaaaga ctaagccatt
     3541 ttaccatgga atgttctgtt tataacatct aattgttgct ctttagttaa ttttatgaag
     3601 ttaactgcat atccagatac tcttatagtt aattgtggat attcttctgg atgttccata
     3661 gcatcttcta aagtagctct atcaaataca tttacattta agtgatgagc attttgagcg
     3721 aagtatccat ccatcattgc agaaagattg tttattcttt cagtcatatc ttttcctaaa
     3781 gcaccaggta ctatagagaa agtattagat ataccatctt gagcatgttc atatggtaat
     3841 ttagcaactg aagataatga agctaaagca ccattagtat ctctaccatg cattgggtta
     3901 gcaccaggag caaatggagc accagctctt ctaccatctg gtgtattacc agttttctta
     3961 ccataaacaa catttgaagt tattgtaagt atagattgag taggataaga atttctataa
     4021 gttttattct ttcttatttt attcataaag ctttcaacta actctacagc tatactatca
     4081 actctatcat cattatttcc gtattttgga taatctcctt ctatttcaaa atcaacagct
     4141 attccttgtt catttctaat agttttaacc ttagcatgtt ttatagcaga taatgagtct
     4201 gcacaaactg ataacccagc cataccacaa gccatagttc taaatatatc tctatcatgt
     4261 aatgccattt ctaatgcttc ataagaatat ttatcatgca tataatgtat tacatttaaa
     4321 gtatttacat ataatgttgc taaccaatca gtgaatggtt caaatttact cataacttca
     4381 tcataatcta agtactcaga agttataggt tcaaatcttg gtccaacttg aacaccagat
     4441 ttctcatcta caccaccatt tatagcgtat aataaagttt tagctaagtt aactctagct
     4501 ccaaagaact gcatttgttt accaattctc attgcagata cacaacaagc tataccatag
     4561 tcatctcccc agtatgctct cattaaatca tcattttcat actgtactga acttgtatct
     4621 atagatactt tagaacagaa atctttgaat ccttgaggta atttagttga ccatagaact
     4681 gttaagtttg gttctggaga aggtcctaat gtatatagag tatttaacat tctaaatgag
     4741 tttttagtaa ctaatgttct accatctatt cccatacctc ctatacactc agttacccaa
     4801 gttgggtctc cagagaatag gttattgtaa tcaggagttc ttaggaactt aaccattctt
     4861 aatttcataa caaaatggtc catatactct tgtaattctt cttctgttac gattccagct
     4921 tttaaatctc tttcaaagta tatatctaag aaagtagatg ttctacctaa agacattgca
     4981 gcaccatttt ggtctttaac agcacctaaa taaccaaagt ataaccattg tacagcttct
     5041 tttgagttag ttgctggttt tgagatatca aatccataag attcagccat ttttttaagt
     5101 tcatttaaag ctgatatttg ctcagttatt tcttctctta atctgataac ttcctcatcc
     5161 atgcaagaaa cttctaatga ttttttttgc tcatttttat cttctattaa agcatcaaca
     5221 ccatatagag caactcttct gtagtcacca attattctac ctctaccata agcatctgga
     5281 agacctgtta ttataccaga ttttctagca gctctcattt ctggagtata aacgtcaaaa
     5341 actccttggt tgtgtgtttt tctgtattta gtaaatatat cttttatttc tgggtctaat
     5401 tcatatccaa aagcttcgca tgaattttca accatcttga taccaccata tggcatgaca
     5461 gctcttttta aaggggcatc cgtttgtaac ccaactattg tttctaattc tttatctaaa
     5521 tatcctggag catatgcagc tattccagaa acagtttttg tatcaacatc taaagtacca
     5581 ccattttctc tttctttttt aaataggacc attgcttcgt cccataattt tttagtattt
     5641 tcagtggcac cagctaagaa agagtcattt ccctcatatg gagaatagtt taattgtata
     5701 aactctctaa catttatttc tttagtccat cttcctgttt taaatccttg ccatgcattc
     5761 attaagtatt tcctccttag atttaaatga taaataatac tattaaaatt aatttttata
     5821 tacttaattt attttatata tttttttaaa aatatatttt ctaatataat aatagcatat
     5881 tattcgtatc ctgtatacat aaaaaataaa aaattgtcgc tttaaagtat aaaacagatt
     5941 atatgttaat aatgtggtga aattataccc atatataaat aaaataaaac aaataaatag
     6001 ctaattaagg agaaaatatt ttttattttt tgtttaggat aaataaattt tattatggaa
     6061 aaaagaaaaa gcatacatct tcacaaactg aatatttatt taataggggg aggtgataga
     6121 ttgtttatca cagtggtatt atttttagta ggtttcctat taattactaa aggcgcagat
     6181 atctttataa attgtactgt agagataggt aaaaaaacga atatatcaga aattatactt
     6241 ggagctacta tagttagttt tgcaacaaca ttacctgagt ttacagtgtc tctacttgct
     6301 tctattgatg gtcatactac tatgagttta ggaaatgcag ttggttctat aatatgtaat
     6361 acagggttag cattagggtt ggttgttttt ataagtccat ttaatgtaga taaaaaaatg
     6421 tttttttcta agtctttact attaatagta tccgttatag ttttaatttt attgagttta
     6481 gatggagtta taacaagagg tgattcatta ttacttataa taatattaat cttttatatg
     6541 gttaataatt atagaagtgt cgttggaaaa tctgatacta aaaatagaaa tattaaaaat
     6601 aacactatta aagacatatc tactaaaaaa gggaaaaatt ataggggttt ttccgtatta
     6661 gaaattgtaa aaatactatt actttttgct acaggattga taatgatgat aataggttca
     6721 caaatcctta tagagagtgg agtaataata gctagttttt taaatatacc tcagggtata
     6781 gtaagtttaa ctataatagc acttggaact tctcttccag agatagtttc gtcgattact
     6841 gctataagaa aaaatcatca tgaaatatca gtaggaaata ttttgggtgc aaacatattg
     6901 aatatagtat cagtaatagc tgtatcagca ataccaaata acataccaat actatctcaa
     6961 aatagacaat tggatatacc attcatgata ttattattat taatagtaat aataccaaca
     7021 cttaaatcta ataaacttag tagaatacaa ggtatattga tgttattcac atattttctg
     7081 tacatatcaa ttttgtattt catgtatatt atttaactat actgtttaaa atattaattg
     7141 cagaatatcc taaaaaagta tataatggat aggttaagat taattgataa cggagaggaa
     7201 taatatatga atataacaaa gtttgaagat ttaccaataa gtgagggaat aaaaaaagct
     7261 atagctgaaa tggggtttga agaaccatct cctatacaag cacagtctat acctgcgatt
     7321 ttgtcaggta aagacgttat aggacaagct caaactggta cgggaaaaac agctgctttt
     7381 agtatcccta tactagaaac aatagaccca aataatagaa gtttacaagc tgtagtgctt
     7441 tgtccaacaa gagaactggc aatacaagta tcaacagaaa taagaaagtt agctaagtat
     7501 tcgcacggaa taaagacatt acctatatat ggtggtcagc caatagatag acaaataaaa
     7561 tctctaaaga gtggtgtgca agttgtaata ggtacaccag gacgtacaat agaccatatc
     7621 aatcgtaaaa cattaaagat ggataatgta aaaatgatta tattagatga agcagatgaa
     7681 atgctagata tgggatttag agaagatata gaaatgattt taagtaagat tccagaagaa
     7741 agacaaacaa ctttcttttc agctactatg ccaagaggaa ttttggaatt aactaagaga
     7801 tatcaaaaag acccagagca tataaaagtt gttagaaaag agcttacagt ttcaaataca
     7861 aagcaatact atatagaaac taggtcatca aataaattag aagtattatg tagattagta
     7921 gatgtatatg accctaaact atctgttgtt ttctgtaata ctaagagaaa agcagacgaa
     7981 ttggtaggag atttacaagc aagaggatat tttgcagatg cattacatgg tgacttaaaa
     8041 cagactcaaa gagatatagt aatggataag tttagaaatg gtacaataga tatacttgtt
     8101 gctactgatg ttgcagctag aggtatagat gttgatgatg ttgaatgtgt attcaactat
     8161 gacttaccac aagatgaaga atattacgtt catagaattg gtagaactgg tcgtgctggt
     8221 agagaaggta tgtcatttac ttttgtattt ggaaaagaaa tgagaaagat gaaagatata
     8281 gaaagatata ctaagtctaa actaataaag cataatatac caacaataac tgatgttgaa
     8341 gagaaaaaag taggtacttt ctttgcacaa gttaaacaaa ctatagaaga aggtcactta
     8401 actaaacaat tacaatggtt agaaggtttc tgtaatgatg aagattatgc aatggttgat
     8461 atagctgctg cacttgtaaa actatctcta ggtgaagaaa tgaaagaaga aataatagaa
     8521 gaaaaaccta gaagagagcg tggagataga aaaggtggta ctggagctaa agatggtatg
     8581 attagattat ttatcaatat tggtagaaat caaagagtac aagcaaaaga tatagttggt
     8641 gctatagctg gagaagttgg aataccaggt aaagtagtag gtactataga tatatatgat
     8701 aagtatactt ttgttgaaat acctaaaaaa gatgcaaaaa cagtaattga aaagatgaaa
     8761 gatattaaga taaaaggtaa taagattaat atagaaaaag caaataagaa gaaaaaataa
     8821 cgtatagtat acaaaactat aattagaaaa tatataaaat aatatattgg atatttaaaa
     8881 agcctgatgt gttttcaaaa cagatagtag ataatctgta agagttaaca gcataaggct
     8941 tttcttgttt tatataagga atctgaataa cttactgtta aatctttgaa ttactgcacc
     9001 tcatttacgt taaggatgga gtattctacc tatttttgat aaaatatatc tatgttttat
     9061 atactatagt tttgaacata gaaagtttaa taaattatag tatatatgtt aatttttaat
     9121 aaggtaagaa agtagaaaga aggatatttt atggatataa taaaaaaatt aagtcatggg
     9181 tgtacattag attgtcatga ctgttgtaaa ttcaatgttt atactaaagg aaataatgta
     9241 gtaaaaattg aaggagataa aaatcatcct tatacaaaag gttttatatg caaaaaaggg
     9301 atggcccatt tagatagatt aaatcataaa gatagaataa agactcctat gcttaaagtt
     9361 gatggagtat ggaaagagat ttcttttgat aaagctatag aaataatggc agaaaagctt
     9421 acatactata aagaaaagta tacatcaaag tctgtcatgc attatgacca atatggaagt
     9481 gggtctgtgc taaaatacat aggagatata ttttttaatt tttatggagg tgttagcaga
     9541 cataagggtg gtccctgttg gagtgcaggg atgcatgctc aaaaatatga ttttggagta
     9601 gctaagagtc atgctataga agatatgtta aatagtaaaa gtatatttgt gtggggaaaa
     9661 aatccagcat atactacaat tcatactatg caaataatta aaaaagctaa agaaaaaggg
     9721 ataaagatag tagtgattga ccccatatat acaaaaacag ctcaaatagc agataagtat
     9781 gtacaagtaa atcctggaac agatggagct ttagctatag ctatggcaaa aattatagta
     9841 gaagataaat tatatgatga agaatatata aactcgtatg ttattggttt tgaagaatat
     9901 aaaaaatatt tatcttcatt ggaattaagt tttttaattg atgaatgtgg tgttaaagag
     9961 aatgatataa gagagttagt ggatttatat actaacaaat attcaagtat aaatgttgga
    10021 tatgggcttc aaaaatataa aaatggtgga aacacaataa gagcaataga tgctttaggt
    10081 gctataactg gtcaaatagg atttagtggt ggaggggtaa actatgctaa taaagtttat
    10141 ccgagtgtta taaattctga cccttacaat agccaatcat atggtgaaga tagggagttt
    10201 tatgtaagta atatcagtaa atttatagaa gaatctttaa aaaatacatc aaataaagta
    10261 aattatgcat cagatgaact tgatatggca ttacataaag taaattacat atcagatgaa
    10321 cttgatacaa catcaaataa agtaaattat gtatcagatg aacttgatat ggcattacat
    10381 aaagtaaatt gtgtatcaga tgaacttgat atggcattac ataaagtaaa ttgtgtatca
    10441 gatgaacttg atatgacatc aaataaagta aattatgtat cagatgaact tgatatgaca
    10501 tcaaataaag taaattatgt attagatgaa cttgatataa catcaaataa aacagattat
    10561 atatcaaatg aattgtataa tttatctaat aagtcaatca aagataatat tcctataaag
    10621 atggctgtga taactaaaag taatatgctg aatcaactgc cagatttagt agaattggag
    10681 agggtgtttt caaaaattga atttaaagta tgttttgata tgtttataac tgatacagct
    10741 actttatgtg acatgtttat accgtgtaca aatacactgg agagtgaaga tataatttat
    10801 agctcaatga ccaatccata tataacctat aatgaaagag ctgtaaagcc agcacataaa
    10861 ttgatggatg aatattactt ctttatggag ctagctaaaa agatgggatt aaatgattat
    10921 ccttttgtag aaaagagaac ttatttagaa aaagtgattg aaccacttaa gcgttttgac
    10981 aaaaatctgg atatagaaaa acttaaaaac aattacttta ctatacataa ccctgttgct
    11041 tgggaagata agaagtttga gactccatct ggaaaatacg agctttattc agaaagtata
    11101 aaaaacttgg gaataagtcc aacacctgta tatataagca ataaatataa agaaatagaa
    11161 gataaaaata tttcttttag attattaact aatcatcatg cagatacttt atttagtcag
    11221 cattttatgg acaaaaaatc tatagctcaa gcatatataa atcggagaat ggctaaaaaa
    11281 gtaggtattg aggacaaaga tattgtgata ttgaggtcaa aaaaagcaaa aataaatgta
    11341 caaataaata tagatgatgg agtaggtaat tatatagtaa aaatgtatgt tggttggtgg
    11401 aagaaacatg gaaatcctaa tagtttaaca gacactggta tatcagattt tgggggtcag
    11461 gtaacatata atgaaagtat ggtagaaata atacgacaaa actagttaaa tttcattgaa
    11521 ggaataaaaa tataattata gaattgatta aaagttacta tttttacaaa actattgaag
    11581 gagggatttt tgatggtaaa ttattcctta gaacataaga atctatacat agaatttatg
    11641 tgctcagaac tagaccacca tgtagccaat gaaataaggg aagaaataga taacttatta
    11701 agtgtaaatc aagtaaaaaa tgttgtattt aattttgaaa atattaattt tatggattct
    11761 tcaggtatag gcgtcatcat aggtagatat aaaaagattt ctaatgaagg gggacgagtt
    11821 tcagtaatta atataagttc acgagttaag aagatttttg atttatctgg gttaaataaa
    11881 attattggca tttatgatac gtatgaagaa gctctaagtt ctttgtaggg aggagtatgt
    11941 gatgaataat attatggaag ttaaattttc ggcaatatct gaaaatgaaa gtttagcaag
    12001 agttatagta gcatcctttg cagctaagtt agacccaaca gtagatgagt tagtagatat
    12061 aaaaactgct gtctctgagg ctgttacgaa tgctataata catggatatg aagaagacag
    12121 ttctaagttt gttttcttaa gatgtgagat agaaggaaat actataaaga ttatagttga
    12181 agatgaaggg tatggaatag aaaatgtgga gaaggcaatg gaaccacttt atacatcaaa
    12241 accagaactt gatagatcag gaatgggatt cacagtaatg aaaagcttta tggacgatgt
    12301 agaggtaagt tctgtaaaag ataatgggac tagaattgaa atgactaaaa aaataaatgt
    12361 gcctaaataa agtccaaaag tgaggtttta ttatggaagt aactgttgcc agagaagaaa
    12421 aaaaacctct tcttagtcat gaagagactc tagaacttat tgaaaaagtt caaaatggag
    12481 atgaagaggc aaaagaaata ttaatatcaa gcaatttagg tctagttagg agcgttgtat
    12541 ctagattttt aaatatagga tatgatagag aagatttatt tcagttaggt tctataggct
    12601 taataaaatc aatatataaa tttgacccaa aatttaatgt aaaattctct acttatgcag
    12661 taccaatgat tttaggtgaa ataaagagat acttaagaga tgatggtatg ataaaagtat
    12721 caaggtcgtt aaagcaaata gctgtaaagg caaagatgga aagtgaagct ttaactaaaa
    12781 aattaggtag agaaccgagt atagaagaat tagctaaagc aatagatgta gaaaaagaag
    12841 atttagtaat ggctatggaa gctaatttca atgttgagta tttgcaagga gttattcatg
    12901 aagaggaagg ttctccaata tgccttattg ataaaataag catgaaagga gaaagtgaag
    12961 aagaaaaagt agtggataac atattgttaa aagacatact tggaagactg gataagagag
    13021 agcgtcaaat aatagttctc agatactttg aagacatgac tcaaagtgaa ataggagaga
    13081 tgctcaatat atcacaagtt caagtatcta ggatagagaa gaaagtattg tctaagttaa
    13141 aagaatatat atcat
//
LOCUS       DAEPXW010000101        13064 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.103, whole genome shotgun sequence.
ACCESSION   DAEPXW010000101 DAEPXW010000000
VERSION     DAEPXW010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13064
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.103"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            77..706
                     /locus_tag="KRM55_002992"
     CDS             77..706
                     /locus_tag="KRM55_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595206.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     gene            681..1085
                     /locus_tag="KRM55_002993"
     CDS             681..1085
                     /locus_tag="KRM55_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBH1595207.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            1088..1564
                     /locus_tag="KRM55_002994"
     CDS             1088..1564
                     /locus_tag="KRM55_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HBH1595208.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            2111..2776
                     /locus_tag="KRM55_002995"
     CDS             2111..2776
                     /locus_tag="KRM55_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBH1595209.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            2798..3730
                     /locus_tag="KRM55_002996"
     CDS             2798..3730
                     /locus_tag="KRM55_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBH1595210.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKSATSVQDSSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            3751..4392
                     /gene="pcp"
                     /locus_tag="KRM55_002997"
     CDS             3751..4392
                     /gene="pcp"
                     /locus_tag="KRM55_002997"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBH1595211.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(4512..4844)
                     /locus_tag="KRM55_002998"
     CDS             complement(4512..4844)
                     /locus_tag="KRM55_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595212.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            5109..5729
                     /locus_tag="KRM55_002999"
     CDS             5109..5729
                     /locus_tag="KRM55_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1595213.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEEIIMTNFIK"
     gene            complement(6044..6868)
                     /locus_tag="KRM55_003000"
     CDS             complement(6044..6868)
                     /locus_tag="KRM55_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBH1595214.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(6879..8282)
                     /locus_tag="KRM55_003001"
     CDS             complement(6879..8282)
                     /locus_tag="KRM55_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595215.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDDGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(8286..9011)
                     /locus_tag="KRM55_003002"
     CDS             complement(8286..9011)
                     /locus_tag="KRM55_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595216.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            complement(9123..9896)
                     /locus_tag="KRM55_003003"
     CDS             complement(9123..9896)
                     /locus_tag="KRM55_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595217.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            complement(9902..10789)
                     /locus_tag="KRM55_003004"
     CDS             complement(9902..10789)
                     /locus_tag="KRM55_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595218.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSGDNIQSVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            complement(10803..11825)
                     /locus_tag="KRM55_003005"
     CDS             complement(10803..11825)
                     /locus_tag="KRM55_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595219.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            12400..12576
                     /locus_tag="KRM55_003006"
     CDS             12400..12576
                     /locus_tag="KRM55_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595220.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT         4802 a         1893 c         1517 g         4852 t
ORIGIN      
        1 tattgacagt attaaaatta aattatacaa taacagtgta aattaactta acaccgttaa
       61 gcaaagaggt gattatatga gtatcaaaga aagacgtaaa aatgaaaaag aagaaatgaa
      121 gaaaaagatt atggatgcta gcatcgaaat tataaaccaa catggatatg aaaatttatc
      181 aataagaaaa attgctacaa aaatagaata ttctccaact acaatttatc tttactacaa
      241 agacaaagca gaaattatca gcgatatgac caataaactt tataacacag tagaaagtaa
      301 tgctattgac attatgaata attgctcatc actaccaata gataaacaaa tcatagaaat
      361 tatgactagc tttataaaaa ctctttctag tgaaccagag atggcaaaat ctatcatgca
      421 tagtagaatg aatattatat ttgcatctga aaatacaaac aatacgccta gcaataatgg
      481 tataaaaatg cttgataaat tcctttccat tggaattgaa caaggaatat tcaaaaaaaa
      541 tatagataaa agctcatgga tgcttataag tgcattgtta ggattcgttt tatgtgttgt
      601 tgaaaataaa ctatattctt tacataattt ttctcaactt atagaaaatt tcttagatat
      661 tttagtggga ggactttaca atgaaaattc gcaacaaggc tactaataaa aagaaaaaat
      721 atgtaaaaat atctattgct ctattctttg tatttatatg cattattatt gtaattgtaa
      781 gcaacttaaa gccagaaaac ttggtagtaa aagatataga tattaataat gttaaaaatg
      841 gcatttatac tggaagtgct gataataact tggtaaaagc tactgtgtct gttgaagtta
      901 ataatggtaa aatccaaaat attaatatct taaaacacga ccatctttta ggtaaacctg
      961 ctgaaaaaat tacaacaagt attattaaac aacagtcttt agatgtggat gctataactt
     1021 ctgcaactta tagcagtaat actatacgaa aagctgtaga aaatgcttta agaaagggag
     1081 aataattatg aatactatta ttatatattc aagtaaatat ggttgtacaa aagactgtgc
     1141 aaatatacta aaaaataaac tatcagataa tgtcactatt gttgatatta ataataataa
     1201 taataaaatt gagttatcaa aatttgataa aattattatt ggaagttcta tatatgttgg
     1261 ttcagtttca aaaaaaatac aagtgctatg taatgataat gtagagttat taaacaaaaa
     1321 acaagttggc attttccttt gctgtggctt ttctgaacaa gcagataaat atttaaaatc
     1381 aaattttcca tcatccttat tagaaagtgc aaatgctatt ggaatttttg gtagtgaagc
     1441 tcgattagaa aaaatgaaat ttttagataa acttattatg aaggctgttt caaaaggtaa
     1501 ttatgacagt tttagaatat cacaggataa tatagataat tttttaataa atcttaatag
     1561 ctaaaataaa gctaattatt tctatgataa attcttttat ttataagtaa tattgctcaa
     1621 aatagtcttt aaactttatc aaaattttat ttttcttagt gaaatctaat gaaactatca
     1681 cttaatatat gctttattaa tcataacaaa aagagagtgt ctaatgaact aaaaaattca
     1741 ttagacactc tctttttgta tgaaatcaaa tatattttta tcatttcaaa agtgaaaaat
     1801 acacttgtct ctatgtttgg cacattctct ttttataata taatatctaa tttaaaacct
     1861 atttcaaata ttgacatata cttaaactat agacttacaa aatcaattca tattagctta
     1921 aaatataatc tttgttattc aaattcctat acacaaccat tatttacttt gatactttaa
     1981 aacatcttcc ctatttttta ttaaatttta taataatagt cctattaacg caaatactat
     2041 aaaaagagtt taactttatc cattaaataa atttaaatta aaacatatag aaatggaagg
     2101 agaacaattt atgataaaac taatcggtat attgatagtt gtaattggat ttatacttaa
     2161 aattgacaca ttatttactg tattattagc aggagtggca acaggaattg ttgcaggatt
     2221 agattttaat caaattttta caattttagg agattctttt gtctcaaaca gaggtgtatc
     2281 attattcata ttaacattgc cagtaatcgg tgtattagaa agatatggtt taaaacaaag
     2341 agctgtttct ttaatagaaa aattaaaaag acttacaaca ggaaaagtac ttactatata
     2401 catgatagct agacaaatag ctggtgctct atcaataaga atgagtggac atcctcaatt
     2461 tgtaagacca cttgttaatc ctatggcaca agctgctggt ttaagtaata gtgatgagct
     2521 aaaagaatcg gatgaagaag ccataaaggc attatctgct gcatcagaaa actatggaaa
     2581 tttttatggt caaaacttat ttgcaggtag tagtggagta ttacttatag catctactct
     2641 gactcaattt ggatacaatg taactggact taatattgta aaggctagta ctattatggc
     2701 agtaatagca cttgtagtgg ctacaatcca gtttacctta tatgataaaa aattaaacaa
     2761 aagtcataaa aaatagtttt atttaggagg aataaaaatg caaaatttta taaacatatc
     2821 attagaaatc ttttacgcac taatgggatt tttaatgatt gttatagcat ataagtcttt
     2881 tactaccata aataacaata agaaatatgg tacatcatta ttttggatac ttatatcact
     2941 gccattcata tttggtagat tgattccagc caatataata ggaataatat taatattatc
     3001 tagtttatta acactttcta aacaagttgt atttgcaaag tatgaagaac cagatgaaaa
     3061 ttttggaaaa gaacaagcag acaaacttaa aaataaaata tttataccat cattaatatt
     3121 agcatttgct gcagtagtag tagctatgag cctttctaat tttgataatt cttctcaatt
     3181 tgcaataggt gtgggttcaa taattgcatt aatatcagcc cttataataa ctaaggcaaa
     3241 atctgctaca tcagttcaag atagctcaag attacttcaa caaatgggac ctgctagtat
     3301 gttaccacaa cttttagttg cactgggagc tttatttact caagccggag tcggtgaagt
     3361 tatttcaacc atgatatctg gtgtagtccc tgctgatagc agattatttg gtgttatagc
     3421 ttatgtatta ggtatggtta tatttaccat gataatggga aatgcatttg ccgcattttc
     3481 agtcataacg gcaggaattg gtattccttt tgtattgtct caaggtggaa atcctgctat
     3541 aattggagca ttagcattaa cagcaggata ttgtggaact ctacttactc caatggctgc
     3601 taattttaat atagttccag cagccttgct agaatgtaaa aatgattata ttgttataaa
     3661 atatcaagct ccagttgctt tggtattaat tatagcccac atattagtaa tgtacttttt
     3721 aggattttaa tataattagg aggtaaaata atgaaaattt tgttaacagg atttgaccca
     3781 tttggtggag aaccaataaa cccagctcaa gaagcagttg aaagggtcaa taataatata
     3841 aacggtgcag aaatcataaa gataactata ccaacagtta tgacaaaatc tgttgaagct
     3901 atagataaag ctattcaaga gcacaatcca gatatagtaa tatcagttgg acaagctgga
     3961 ggtagatttg acattacacc tgagagagtt gctataaata tagatgattt tagaataaaa
     4021 gataatgagg gtaaccaggt tatagatact attataaaag aagatggtga acctgcatat
     4081 ttttcaaaat tgcctgtaaa agctatggta aaacatatga atgaaaataa aattccagct
     4141 agtgtttcaa acactgcagg aacatttgtt tgcaatcatg tgatgtatgg aattctttat
     4201 atgatagaca agaaatatcc taatataagg ggtggattta tacacatccc atatacaact
     4261 tcacaagtaa tagataaaaa aaatacacca ttcatgtctt tagaagaaat agtaaaaggc
     4321 ttagaattag ctatagaagc ttgtattata tataaagaag atgtaaaaga aattggtggt
     4381 gaaatttcat aataaatttt ttagtatttt tataaattaa aaatactaac tattaattta
     4441 aatatagact gtgagtagat tattcaaaca attttactca cagtcttttt atggtatcta
     4501 cagatacaaa attaaggtct attcctctct ccccactcac acattgcatc taaaattgga
     4561 atcagagatt ttcccctttc tgatagacta tattctacct taggaggtat ttgaggatat
     4621 tcagtacgaa taatcaagtt atctgcttct aattctttta atgataaact caaagtttta
     4681 taggagatag tatttatata acgttttaat gcattatatc ttacaacttc aaattctaca
     4741 agacagtaaa gaattatcat cttatattta ccactaatca gtgaaagtgt ataactaaat
     4801 cctgtttcac ttaaatctgt atttgatata cagtctatac tcatatatta cactctcctt
     4861 ttggttagta ttgaacaaaa atgtgcgtac ttgtttttag aataatttat aataaaatta
     4921 tagtgtaaga ataattgaaa gtcaatttta taataggagg tgtatttact aaaaaaaagt
     4981 tattttaaat aggattctaa gattagacat ttctatataa attgataata ttcatgaaaa
     5041 tcctatttta taaaaaataa tatctcttag aaaatctatt aaataaaatt cattggagga
     5101 aatttataat gaaagtttta ttgataaacg gtagcccaaa ccaatatgga tgtacttata
     5161 cagcactaaa tgagattact aaagtattga gtaaacacga tattaaaaca gaaatactgt
     5221 atttaggtaa agaaacaatc ccaggatgta ttagttgcgc atcctgtttt gaaactggaa
     5281 aatgtattcg aaatgataaa gttaatgaat tgattgaaga tctggataat attgatggta
     5341 ttattattgg ttctcctgtt tacttttcta gtgcaactgg tcaattaact tcttttcttg
     5401 accgtctatt tttcatagct gggagtcgca tggctacaaa attaggtgct tcagttgtgt
     5461 catgtagacg tggtggtgca agtgcaacat ttgaccaact aaataaatat ttttcaatca
     5521 gcaatatgcc tattgtatca tcacagtatt ggaaccaggt acatggcttt actccagagg
     5581 atgttatgaa ggatgaagaa ggattacaga ctatgcgaac tctaggagaa aacatggcat
     5641 ggcttcttaa gtgtatatca gcaggtaaaa aagctggaat taaagaacca caatatgaag
     5701 aaataattat gactaatttt ataaaataaa taaaaaatgt actaatatta attaaaacaa
     5761 aacactaatt tataaataaa ataagcataa atgtaggata aaaagcacta aaacagaggt
     5821 attgaatttt atatcaaacc tctgttttat tattacatta ataaccaaac catgtataac
     5881 atcatatatt tctaaataaa ttatactaat gttattgaaa ttacaataac tgaatttctg
     5941 ctcataaatt taaatattct acaaatctca tctaaataac aattttaata gacctaaaac
     6001 aatcctcata ttgttcattt tgtattaaaa atatcactta caatcaaaaa ccatttatta
     6061 agtatattcc taagatatac aatatatata catggattgg atagtataaa taaaataaat
     6121 acttcatact cttccctttt tctccattat aaagtaacat taaaggtaga gaagcaatca
     6181 tcatccattg gtaattttgt aaaatagaat tttttaaact ataatctcca tttgacattg
     6241 ttgtaaatat aaatatacac attaaaacat aacaaatact caaactgaac tttttacctc
     6301 tacacaaata aaaaataatc ccaagtataa tccaaattgg tccaccttct actaaaaatg
     6361 gtactggtac caaaatcata aataaagcaa taactctgtt agtgacttta aaaagtaaag
     6421 ctactgtaaa tattcctaaa attataggaa tgattatcat caataatcct ataataaaat
     6481 atttaatttc tttctctttt ctaaatttct ttatgaactc tattgcttgt aaataaatcg
     6541 ctattaaaaa taatgttgaa aaaatgttat ttataattat agctccttct ggatgtgaaa
     6601 atacattatt aattatttga tttcctatag ccataataac agaccaaata tacaatctac
     6661 ttatatattt ttttctgtta ctagtgtgat aaaatccttc aacagccatg aatataaaca
     6721 gtggtgctga tattctgcct acccaatgaa accaaattgg tatttgcatt gtttgtggca
     6781 taaatgctgc tatatggtca aatgtcataa atattaatgc taaaatctta atagtaaacc
     6841 cacttatacc ttttttaaaa aaatccatat catatctcct aattttgttt tatctctata
     6901 ataatttttg ttcctattcc aatttcacta cttacataaa ttttaccttt atgaatctct
     6961 attatttctt tagaaatagc cataccaaga cctgaacctt tatgcatctc acctgtatta
     7021 gtacctctat aatatttttt aaaaatatgt ttcaaatcac ttttgcttat tccaattcca
     7081 tcatctttta ttataatttc tatattatct ttttttacaa tttctacact tatcaaagtt
     7141 ccttcgctat tatgaactat tgaattaaat ataagattgg ttatagccct tctgaataag
     7201 attgaatcta catatacttc aattaaatct tcattacttt caaattcaat attcctattt
     7261 ttatatctat tatcatttaa aatatcaatt attatatctc tgactaaact gactaaattt
     7321 atttttttct tgtccagaac tatagtatta ttttttaatc gagtagataa atttaaatca
     7381 tcaactaaat cttttatata cttagactta ttatatataa tttctgtata ctcttgtatt
     7441 tcatcttctt caaactcata atctttgtca ttaattatct ctgcataccc ttgtatagat
     7501 gctagaggtg tctttatatc atgtgttata tttgccaacc attcctctct caactcttca
     7561 ttttcttttc tctcaacttc atttactctt aaagtatcag ctaacatatt tatattttta
     7621 aaaacttctt catatatacc tctgtcctta agatataaac tataatttcc attagccata
     7681 gtctcaatac tccatagtac gcttgaaatt ggttttgtaa gttttctact aaataaatat
     7741 cctacaccta aagctaccac gctatcaatt actagtgtta taatgataac tttatttaaa
     7801 gtttttttaa tgttattttg agaataggtt aaaattattc ttgatatatc tctactaggt
     7861 atacctacta ttatgtttag atgttttttg tttaaatatt tttctaatac aaaattaaca
     7921 tactttgttt ctatatactt gtaattattc accatttgaa agggtgtata ttttttggga
     7981 gtatcctttg gcacatttac tccataaact tcctctccta aatcatttaa aacctgtatc
     8041 caggaatttg atttttctaa tttttcagct ccaatcttag atagtttaaa ttctccatct
     8101 ttttcatata aatctttttc aaaagaacgt gcaaattctt caggattatt tccagaatct
     8161 acaactttaa aaaaactatt agttgaaatc acatacaata tagatatgat atttataatt
     8221 actactgata tagctacaaa cacaattgta aatataaaat ttctagtaat cttccacttc
     8281 atattctaat cttcctttac tgctaattta tatccaagac cttttattgt cagaatatat
     8341 tcaggctttg aaggattatc ctctaatttt tccctaattt ttcttatatg aaccattata
     8401 gtattgtcaa atccaacata atcttctccc cacactttat cccatagttt ttctttactt
     8461 ataatttgat tttgattatg tgcaaataaa gataggattt ttagttcctt tgcagacagt
     8521 cctatagatt ttccatcttt tataagttct gccctacttt catttaatat atatgggcca
     8581 aatgatataa ttttttcttc attattattt agatttttac tttcgttttg agcatcacta
     8641 aaataactta atcttctcaa atgcgcttta actctaaaag ccacttcctt agggctaaaa
     8701 ggttttgtaa cataatcatc tcctccaatc gctagtccaa gtaacttatc taattcttcg
     8761 gttttagctg ataaaaatat tattggagaa ttggaggttt ttcttatttc tttacaaata
     8821 tcataacctt cgccatctgg taacataata tccaatacaa tcaaatcagg attaatactt
     8881 ttaaataatt ctaatccttc ttttttagtt tttgcagtat atatattatt aaggccctct
     8941 ttttttagga cagtttctaa aagcttcaat atttctactt catcatctat tattaaaaca
     9001 cgattttcca taaacaacct cctgtaataa tttacatata tattagcata tattttatct
     9061 aaaattcatt tatcttattt ttaattaaac taaaatacaa ataaaattac tattattttt
     9121 ggttaaaacc ttttgcttga tgtaaaattt tcatacgtta ttttagttaa cactatcatt
     9181 aatataattg agattactat agaaaaaact atcaaaatac ttggtacatt atacttaacc
     9241 atttgttggc tcatcataat ccaatttgga gtcactgaca taaattttat agctttatct
     9301 ggtataaaac ctacactaaa gtatggaatt gccattatca atccacctag tataaatgga
     9361 attacagccg atttaaatat agatgaaagt gttaagccta tttgtgcaaa tataaaagaa
     9421 gcaaaaatag tagtcaatat aacaattata tacatttgta ttactgtaag atttaaatta
     9481 ctatttccaa agtaccataa gttatgaatc gattcattta aatttttaaa atcaaaaaaa
     9541 ctaaaacctc taattcctac taacaatata aaagaaatat taataataga taaaattaat
     9601 ccattagcta ctagttttga taatactact gatttttttc cctttttagt tgtatttatt
     9661 aaacctgtca tattagaatc atattcttta atgtaatttc cagaagttat tataaacatt
     9721 atcaaaccta ttagaggtat tgagccttct atcttgtaaa atatatctgc ataagtatct
     9781 aaaacatcaa actttctaat cagaaaaaat ccaaaaaata ttaaaaacag ccaaattatc
     9841 caaacactct ttgattttaa tatttttatc atttcagctt taactaaata catcatttct
     9901 actacacctc ccttgcatct tccaaatcaa aataaaacat gtatacatct tcgaattttg
     9961 cttgaactga ttgtatatta tccccacttg gaatatcctc tgaaacaatt ctaagtacta
    10021 ctgaatcaat atcactttga atacttacaa ccttatattt agattgtata tcatcaactt
    10081 cacattcatt tttaacttga acattatata ctttattttc catgtgactt aatatgtctt
    10141 tgtgtgttcc tttcattaga agtttgccat ctttaatcat tattgtttcc tttgcaactg
    10201 attctatatc ggaaattata tgagtagaaa gtattattat cttatctcta gacatttttg
    10261 ctattaaatt cctaaatcta gctctttctt gtgggtcaag acctgctgtt ggttcatcaa
    10321 ggactattat cttagggtcg tttagtaaaa cttgtgctat cccaactctc ctcttcatac
    10381 ctcctgaaaa ttttcctata gacttatttc tcacatcata aagacctact aaatctaata
    10441 attctcctat cttactattt aaatattttc cccttaaacc ttttaaagct ccaatatact
    10501 gtaaaaattc ttttgctgta aaatttttat aaactccaaa ttcttgtggc aaatatccta
    10561 aaatatttct ataatcagca tccattttaa atatatcctc accattataa agtatctgac
    10621 cttcatcagg ttttatcaac gttgttattt gtttcattaa tgtagatttt cctgctccat
    10681 ttggtcctag aagaccataa actccatttt ccagagttac tgtaatcttg tcgtttgcta
    10741 cttttttacc atatatcttt gaaagatttt ctatttctaa tttattcata ttaactcccc
    10801 ttttatctac ttatataatc tgattttatt actaaaaaac ataatgacat agcacctatc
    10861 aatattgcca tcaaaagtcc tattgctata ttgacaatgt ctatattcac tttaaatatc
    10921 ataatatcac ctagataatt tcctattatt ttattaaaac caaatatcaa atcataataa
    10981 tttacatttg atacaactga aagtaatttt ttaggtaata tatggattac cgacattatc
    11041 ttagttatag atataataaa tataaaaaaa cttattgaag atattgaaga cttacttata
    11101 aaagacccaa atatggctat catggcccat ccttcaaaca tcaaaagctc tatgcctata
    11161 tttaatatta catactttgt tatacttaaa ttagttttca atgcaactac attgtctact
    11221 attctaaaag attctaagtc tccattaaca ggtactcctt gttgcataca agttataata
    11281 aatattccca ttaaataaac agaataaatt actaatggaa ctaataaagc aacaaatatt
    11341 ttagacttta atgctttttt cttctctttt gatgatagta tgatatcttt taccgaagta
    11401 acgacttcat ctacataaat attagatata attatagata taatgattaa cattcctaca
    11461 tttataagtg aatttgtaac tctatagtta aatactttcc aaaaactaat atccttatat
    11521 tcattcacac ttagattatc aagttttttc tttgacatta attcaatttt tttagaaaat
    11581 tcacctgtat ctgtttgatt tgaaaactgc tttaaaacat taatcttatt ttgaaatttc
    11641 tcattaccta tgtctatacc acttctcgta tcttctatac gtcctttttc tttatctata
    11701 taataacttt ctgtttctaa aacaggcgta ataaagatac taatcattag tattaacact
    11761 aatatcccta gagatataaa catactctta gatttagcca atttttttat ttcccaattt
    11821 accaatatat ttctcctcct aaatcatttt aattacacat atatattaaa acttaaatct
    11881 tatataaata taatactaac cttaaataaa gcttaaatta ttttataatt tataggtgtg
    11941 tttattattg gagttacatt tattattttt ctgggaaatt atacattttc aattattttt
    12001 attatttttg atatttttat tgattggaaa ttttattgtt gttcaaattg tagttattct
    12061 ttaaatttaa agatggagtt ttttaagaat agaacctact gtccttatta tggaaagatt
    12121 attaaatagt tgcatataac tttatttatc ttgaatctta tttttaaaaa caattataat
    12181 tttagaatat tttctattct caaacaagca tgttgaataa tggagcatct tctagtatta
    12241 tatacttgta gaataaaact aaattggtaa aactgggaat atttaacctt aaggagttaa
    12301 gttatagaaa ctagtactaa aaaattttat aaattatgtt aattgactaa tagaatgcga
    12361 ctttttattt ttactaaatt ttttaggggg atggataata tgtttattgg agaaatagac
    12421 aaatgtacac atatactaac tgcttacatc agtagttcat atgattattg taatttttta
    12481 gatacacagt tagatgattt tatatcagaa tatggagaaa cggtagttga aacctgctta
    12541 catcaagtct tattattagt aagtagatac aattaaaact aaatttttct agaaaaacct
    12601 ttttagattt atctactcta ataaatatat aattttttgt actttataag taactataac
    12661 ttctgctaaa gtaaagatgt attgggagta catctttact ttcccattat agaagttaaa
    12721 agcatacacc ataaaattaa tcatccaata caaattatat atttcctatg tctaacttaa
    12781 tttacaagaa tcattctata tgcatattct gcaatccact aaacatggct ctaaaccttt
    12841 actattttat acattctcta taaatcatac aaatcatata taaaatcccc ctaatatgtt
    12901 taaaccacct ataaaataac accaatattt agaatattca atatcaactg cataactggt
    12961 caataaaaac gtataactag acaaatttca atatttatat aaataataca agaaaaacaa
    13021 gcattttatt tatataagtt tttcattttt tgtttatatt aaaa
//
LOCUS       DAEPXW010000102        12793 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.104, whole genome shotgun sequence.
ACCESSION   DAEPXW010000102 DAEPXW010000000
VERSION     DAEPXW010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12793
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.104"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            155..556
                     /locus_tag="KRM55_003007"
     CDS             155..556
                     /locus_tag="KRM55_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595221.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQIGK"
     gene            599..892
                     /locus_tag="KRM55_003008"
     CDS             599..892
                     /locus_tag="KRM55_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBH1595222.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            907..1347
                     /locus_tag="KRM55_003009"
     CDS             907..1347
                     /locus_tag="KRM55_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBH1595223.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(1439..1912)
                     /locus_tag="KRM55_003010"
     CDS             complement(1439..1912)
                     /locus_tag="KRM55_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1595224.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(1912..2700)
                     /locus_tag="KRM55_003011"
     CDS             complement(1912..2700)
                     /locus_tag="KRM55_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1595225.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            3028..4272
                     /locus_tag="KRM55_003012"
     CDS             3028..4272
                     /locus_tag="KRM55_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH1595226.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            4595..5692
                     /locus_tag="KRM55_003013"
     CDS             4595..5692
                     /locus_tag="KRM55_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH1595227.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            5683..6381
                     /locus_tag="KRM55_003014"
     CDS             5683..6381
                     /locus_tag="KRM55_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1595228.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            6384..7448
                     /locus_tag="KRM55_003015"
     CDS             6384..7448
                     /locus_tag="KRM55_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH1595229.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITSMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            7631..8335
                     /locus_tag="KRM55_003016"
     CDS             7631..8335
                     /locus_tag="KRM55_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595230.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            8328..9650
                     /locus_tag="KRM55_003017"
     CDS             8328..9650
                     /locus_tag="KRM55_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595231.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            9837..11210
                     /locus_tag="KRM55_003018"
     CDS             9837..11210
                     /locus_tag="KRM55_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595232.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEAFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(11582..12520)
                     /gene="pdaA"
                     /locus_tag="KRM55_003019"
     CDS             complement(11582..12520)
                     /gene="pdaA"
                     /locus_tag="KRM55_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH1595233.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT         4803 a         1488 c         2146 g         4356 t
ORIGIN      
        1 attataaatt tattatagac tacacattga agtaaaagaa gtagctaaaa ttattccttt
       61 tatttttgtt ttttgtatct atttggtata atagtattag agcgtataat aatttaggca
      121 aaatttttta aggaagacta gaggagaata taaaatgaaa aaatgtcttt actgtaatag
      181 ggatataaag tcaccaaata ataaattagc tataaaatat gatgacaata tgaatatata
      241 tccatgtcgt gcagaatgta aggaaaaaat tgaagaatat atagcaaaaa aacctacata
      301 taagtttata aatatattag aggttctttt aggtgtgggc ggaatattct gctttttgag
      361 taaatggact attgcagccc aagttgtact tggaattgat gcactggtta tatttttatt
      421 cccattggca ggatttaaga tgaatggaaa gttaagtatg gaacaaacta agaatcaaag
      481 taggtctatt gcaatatcaa ttttggcatt tatagtaata ataactgtat tatattttaa
      541 acaaattggt aagtagagca taattgtata agacatcatt agagtatgag gtgagtttat
      601 ggaagaaaga aaattagcac caaacaatga gagggaagct ctcataaaaa gattaaaaag
      661 aatagaaggt caagttaagg gtatacaaaa gatggtggaa caagaacgtt attgtgttga
      721 tatattggtt caaatatctg ctataaggtc tgctataaat agagtaggca caattatctt
      781 agagaatcat ataaaaggat gtgtagcaga aagcattaaa catgatgatg ctgataaaac
      841 tgaagagatg ataaaagagc ttatggatac tataaataaa tttacaaaat aaggaggcgg
      901 ttagttatga atcaacaagg atttattatg gaaattgttg atgatagaac tgcaaagtta
      961 aaaatgcaaa gacattcagc ttgtgctgct tgtggaaaat gtgctactac aaattcagca
     1021 gagtcaaaag aaatattagt agaagtagac aacacaattg gcgcaaaagt tggtgaccat
     1081 gtagaagtga gtatggataa tatgaatgta ttaaaagcag ctgtaatggc ttatataata
     1141 cctcttatag cacttcttgt aggaacaata gggacttatt atatattggg ggcaattgga
     1201 atgacaactg gagttgaagc cataagtgga ttagttggaa tttgtcttac aataatctgt
     1261 tatttatact taaagaagaa tgacaaaaaa tttagagaca gtagagaatt tataccagta
     1321 ataacaagaa tattaattga cctttaagat aattataatt aaaaaatagc aatgtgcttc
     1381 ttaaataaat actcaatacg tatttgtaga gtttaagtac attgctattt ttatattttt
     1441 attttgattt tctgtaagga ataaagtttt ttctgatttt caaaagattc aatgttctta
     1501 caaaagaagt tacaactaat acaccaagtg ctattgcagc acttagaaat agcgcatctg
     1561 taccttttga catagccaaa gaataatttt tctgaatcaa agacaacatt gtattatata
     1621 gcccaattcc tggtattaga ggaagaatac ctggaattac gaacacaata gctggttgct
     1681 ttagttttct tgctaaagtc tcactgcacg ctgagaccaa agcagcagcg ataaaacctg
     1741 caaaaactgc atttgtagta aaattaaata aataaacata tacaatccaa ccaattccgc
     1801 cagttactcc agctggaaga agtagatata gtggagcatt aaagaaaaca gcaaatccag
     1861 cagttgcaac acctgaaaat aaaaaatgca aaatcataga catatcagtc attagaaagg
     1921 acctcctatt ctataccatg tatcaaggac aaaaccaact ccagaagcaa ttgcaataat
     1981 aatcatagca gcatcaaaag cacgagaaat tcctgatatt aaattccctg atattaaatc
     2041 tctaatagct tttataaaag caactcctgg gagtagtggc attatagcgc cgactataag
     2101 cattttaggg tcatctaaaa tgcctatttc aactagtaga actcctgaaa gtgcaattaa
     2161 aaaagaagat actaaacagg aaaatgcaga tattgcactt atcttcatcg ttttatcata
     2221 agtaattgca gcaaagattg ctattataaa cgtaagtata aaatttaata cataattccc
     2281 tccaagcaaa caagcaaaac aagcagatgc aattcctgta caagagtaaa ataaccataa
     2341 aggataaggt tttacatctt ggatttcata aagacgtgca atggcattat caatatcata
     2401 ctctttgtca ctaacaaatt ctcgagaaaa actgtttaat aaagaaatct tatttaagtt
     2461 tatacctctt gattgaatcg ttttcataaa cgaaaagcca tcaaatttct catctgaaat
     2521 aattattact gtaggagttg taaaaatatt tacatgataa aaccctcttg acctgcatat
     2581 tctaaggaca ctgtcttcaa ccctagatgt ttcagctcca ttttttatca tcagttcccc
     2641 tacaaataga gctagtttta gaatattttt cttatattca agttcctcat tttgattcat
     2701 aaatacacct ccaaattaaa aaacgtaata ttgaaattat atcaaatttt taagtaatat
     2761 tccttaatat ctatacaaat atattatctt ttttttgttt caaaatagtc acatttaaat
     2821 tatatccaat taaaagaatt agacaatatt atttattata ttttaactta aaaataaaga
     2881 aagtaactat gttaaatatg gaaaaatggc aaaacacttg actattaatt ggtaaaggac
     2941 tataataata aattatcata ttgataaaaa cgaaaattat gaaatgtctg taaaaataaa
     3001 atttaaataa taactaggag gagtaatatg tttgagaact tgaaaaaagc ggaccctgag
     3061 atttatgaaa gtatgaaaag agagttaaaa agacaacaaa gaaatattga attaatagca
     3121 tctgaaaaca tagtatcagt tccagtaatg gaaactatgg gaagtcatct tacaaataag
     3181 tatgcagaag gttactcagg caaaagatat tatggtggat gtgaatacat agatgaagtt
     3241 gaaactcttg caatagatag aatcaaaaaa atatttggag cagaacatgc taatgttcaa
     3301 cctcattctg gagcaaatgc aaatattggt gtatattttg ctatgttaaa accaggtgat
     3361 gttgttatgg gaatgaattt atctcaaggt ggacatttaa ctcatggtgc tccagttaat
     3421 atttctggtc aatattataa attttatgaa tatggtatag ataaagacag tggacttata
     3481 gattttgatg aagttagaaa gatagcacat gaagtaaaac ctaaaatgat agttgcagga
     3541 gcaagtgcat atcctagaga aatagatttt aaaaagttta gagagatagc tgatgaggtt
     3601 ggagcattgc ttatggtaga tatggctcat atagcaggtc ttgtggctgc tggtcttcac
     3661 caaaatccat gtgaagtggc tgattttgtt acaacaacaa ctcacaaaac tttaagagga
     3721 cctcgtgggg gtgttattct ttgtaaagaa aaatatgcta aagacataga caaagcaata
     3781 ttccctggta ttcaaggtgg acctcttgaa catataattg cttctaaggc agtttgcttt
     3841 aaagaagctt taagtgatga gtttaaagaa tatcaggtac aagttgctaa aaatgcaaaa
     3901 gccttagctg aagaacttat taaaagagat tttaaattga tttctggagg tacagataat
     3961 catttaatac tattagattt gactaataaa aatataactg gtaaagcagc agaaaagaga
     4021 ttggatgatg cttatataac agctaataaa aatacaattc catttgaccc aaatggtgct
     4081 cttgttacaa gtggaataag acttggtact ccagctgtaa ctactagagg tatgaaagaa
     4141 gaagatatgg caataatcgc tgaggctata gacctatgtt taacttatga tgaagaatct
     4201 aaggctagaa cattggttgt tggtttaact gaaaaatatc ctttatatga agaatataat
     4261 attatggatt aattataaag aacaactaaa taaaatacat ttaaataatt acaatgattg
     4321 tgtatgtatt tgaatatatt tagatataaa aaaggtgtct caaaatgaac tttttagttt
     4381 atgaggcact tttttgtatg gaatcgaaca tatttgtatt atttaaataa taaaaaatat
     4441 ggttatctct atttttagat ggtctctttg tattttttaa ttaaaacttt aagatttctt
     4501 aagaattata ctaggttttt ctaaagattt aaagtctata cttataagta tagtaatcat
     4561 atgaaaagaa aagctttaac gaggagggaa tcttatgaag gtattaattc ttacaggaaa
     4621 atttggtatg ggtcattact cagcatcaaa ttctttaagt gaagatataa aagcaaaatt
     4681 tgataattca gaaataataa ttaaagatat atttgagtac attatgccta actattcaga
     4741 taaaatgtac aagacttttt ctattcttgt aaatcgggga agtagtcttt ataatttgtt
     4801 ttataaatgt gctgaaaatg gaaagaaaga tataaaattt actttttcag attatttttt
     4861 aaataaatta gatacattac ttcatgaagt acaaccaaca gtagttattt caacttttcc
     4921 attttgttct caattagtat caagatataa ggaaaaatat aactcaaatc ttcctttaat
     4981 aacatgtata actgatataa gtagtcactc agaatggatt agtaaaaata cagactgtta
     5041 tttagtagct agtaaatcta ctaaggaaga acttgttttt aaaggaatag atgaatctaa
     5101 gattaaagtt aatggtattc cagtaaaaaa agaatttaaa agaatagaac atgtaaatca
     5161 ttcaactaaa aaaaatattc ttataatggg tggaggatta ggattactgc ctaaatcaga
     5221 acaattttac aaagaattaa atagtttaga aggagtaaaa actactgtaa taactggtaa
     5281 taataaaaaa atgtactata aactatatgg tagatatgaa aatatagagg tagtaggtta
     5341 caccaatgaa gtatataaat atatgaaaga ttctgacctt attatttcta agccaggtgg
     5401 aataacacta tttgaaacaa tttattcaga acttccaata ttggcattta atccattttt
     5461 acaacaagag atagataatg ctagttttat attaaataat gaaattggga gaatacttgg
     5521 taaaaataaa aaatactatg tagatgagat aaaagattta atttatgatg atgctactct
     5581 taaagaaatg agcagtaaca tgaaagaatt aaaaaaacaa tttgataata ataccttaga
     5641 gaatatttta ttttcacttg atgaacaagg agcgtgtaga gaatgtatgt agtaggttta
     5701 attatcgttg ttgcattgat ttttttagtc cattcaatta tacctacata ctataataaa
     5761 ctattaaata aagaggtatt aaaaaatatg gctggagaaa atgaaattgc acttacattt
     5821 gatgatggtc cagataagag atatacagaa aaattactag atgtgttaaa agaaaatgat
     5881 atacaagcta tgttttttgt agtagcaaag aatgctgaaa aagagcctga aattataaaa
     5941 agaatgttga gagaaaatca tatagttggt ttacattcat tggaacacag aaatgcatgg
     6001 ctttatagtt atagttatgt taaaaaagat tttattgaaa gtacaaatat aatgaaaaat
     6061 ttaggtgtag atgtaaacta ctatcgtcca ccatggggtc atactaatat attttcaaat
     6121 tcatttgtta aaaaatataa tctaaaaatg actttgtggg atgtaatggc agaagattgg
     6181 gagaaagata gtacagtaga cattattata aacaagttaa tgagtagaac aaaagaaaat
     6241 tctataattt gtttacatga tgcaggtgaa aattcaggtg gtgcagtagg tgcacctgag
     6301 cgtactattg aagctttaaa gatagctatt ccaaaactta aagccagtgg tttaaagttc
     6361 gtaacaccag aaaggatgta gttatgataa gtaaaactga aaagaaaaat aaatgcctag
     6421 gtagtgtagc ttttttagtt ttactaatgg gcataacagg atattttgtt tttagagggc
     6481 agtcagttga atcattgata aaatcattaa aaggtgcaag ccctatgttt atactaattg
     6541 gatttgcaat gatgtttata tatgttgcct gtgaaggtat aaatatatac ttaggtatga
     6601 aagctttaaa ccaaaagact actcttttaa aatgtatggg atatgctttt attggatttt
     6661 attttagttc tattacgcct tcagcatcag gtggtcaacc agcacaagtt tattatatga
     6721 aaaaagacga tataaatata tcatattctt cacttatact attagtcatt gttgttattc
     6781 accaagtagt tatactggca tatagtggaa taatgttcat tatggaacgt gagtttatat
     6841 taaataatgt aagtggtatg aacattttac taatatatgg tgtaataaca aatgttgctc
     6901 ttgtcattgg agtaattgca attatatttt caaaaaaact tgtaaacaat tttataatat
     6961 caataacaaa tttattaggt aagttaagaa taataaaaga tgttgaaagt tcaagaaaag
     7021 ttataatatc tcaaattgaa gagtatgtta aaggtgctca atatataaag cagaatccaa
     7081 aacttgtagt ccaaatttta gtcataacta ttgtacaaat aacatctatg tttttagttc
     7141 ctttctttgt atacaaagct tttcatctat caacatatac tgtatttgag atattagcga
     7201 tacaatcctt gcttaatatt gctgtttctt cattaccatt gccaggggct gttggagctt
     7261 ctgaaaatag ttttatgaca ttatttaaga tatttttccc tggtcactta ttagttccgg
     7321 caatgttact tagtagggga ataagttttt atgcatttgt agctataagt ggattgatat
     7381 gtatagtagt acatgtaaaa tcttctgaaa aagtaaaagc agtgaaaaaa gttgcttatg
     7441 taagataata ttatatagat tatttttatt aatatgtcaa tttgtgtgta tattttaatt
     7501 aagctttaaa catgtttaca ggagtagaaa ctattaaaac gtgtgacatt gctaagcttt
     7561 tgctaataaa gtataatatt ttatatagtt tgaaatattt aagaaatata gcaaaaaaag
     7621 gagcttggtg atgaataaag agattccaaa aaaaatttta gtagctgatg ataatcctga
     7681 gattagggaa atcgtagaaa tacttttaac tggtgaaggt tatgaagtta ttatggcaac
     7741 gaatggagaa gaagctgtaa acttagtaga tagtacgatt gatttgatta ttttggatgt
     7801 tgtaatgcct gtaaaaacag gatttgttgc atgtaatgaa attagagaaa aaacgacagc
     7861 accaatatta tttttaactg caaaaactca agactctgat aaagttattg gattttcagc
     7921 aggaggagat gactatttat caaagccttt ttcatattct gaactaattt caagggttaa
     7981 gtcgctactt agacgttatt atatatacca gggaaaggaa aaggaaagag agccaaatat
     8041 attaaaaaca aaagagttat gtgtcaattt agatactcaa gatgttacac taaatggaga
     8101 acctgtgttt ttgacaacta tagaatatag tatattaatt cttatgttga aaaatagaaa
     8161 aaaagttttt tcgtctgaaa atttatatga aactatttgg gatgagcagt atttttatac
     8221 agcaaataat acaataatgg ttcatattag aaatttaaga aaaaagttag aaaaagacca
     8281 aaaaaatcca caatatataa aaaccgcatg gggaaagggg tattatattg attaacaaaa
     8341 ttaagccatc taagttggga gttatactat tgatatatgt agtaatctca gctgcagtgg
     8401 ctttcatttt aaatatacca ttttactctg ctgttgaatc tatagtaaaa gatgtatcag
     8461 aagggaaagt atattttaaa agagaagtaa atcaacttat ggataatttt caaacttatg
     8521 tgaataacaa tggtataaga gcagatgatg gagatgatat agcaaaatgg aatagtgata
     8581 attggtttgt ttctatgaag atatataaag gaaataaggt tttttatgat acattatact
     8641 atcctaatga agtacctgat aagagtgagg aaaatgagtt ttatagcagt cccatggcta
     8701 gaaactatga gatacaattt tctgatatta aagctaatat agttgtagta gctttattta
     8761 gatttagatt tcaaaatttt atagaagcaa tttctattac atttatggca cttacattta
     8821 ttataacatt tttactgttg tttagtagaa agataaagta cctaaggaaa atagaaatgg
     8881 gtataaagat agtagagagt ggcagtttaa agtatagaat cccagtaaaa ggtaatgatg
     8941 aattatcatc acttgcatct agtattaatg agatgagtca tacattggag aatcaactta
     9001 taaaagaaag ggagatgaag aataaaaata aagatatagt aacttcgata tcacatgatg
     9061 ttagaactcc attaacgtca gtaatttgtt atttagattt gattaaagac cataaataca
     9121 atagtcctga gcaattggaa caatacataa aaaatgtaag gtctaaagca tatcaaataa
     9181 aagatttaac agatgacctt tttacgcatt ttgttaattc tggagaggaa gtttcaaaag
     9241 ggtatgaaaa aataaatgct aatgaattta tttttcaatt acttttagat agttcatata
     9301 cattggagga gaaaggattt catataacaa tagaaaatga actttataac caatatcata
     9361 tttatgtaga tgttacacaa tttagaagga tatttgataa tttatgttct aatataataa
     9421 aatatgctag gaaagataag cctatagtat ttttaattaa agtagaggat tctaaattac
     9481 taattataca aaaaaataga gtaagtaatt tttctaagaa tgtagaaagt tttggaattg
     9541 gtataaagaa ttgtgagaaa atagttgcat atcataatgg aagcataaat gtaaattcag
     9601 atgataaaga atttgctatt gaaatatcta ttccagcaaa agaatcataa aaatttaaat
     9661 tatatattgt gtaattgcta ttatatattg tgtaattgct tatgtaaaat tctatgaagc
     9721 aggaagcatg tgactttagt tatgggatgt tcaatattgt gtacctctag gcaagtaaca
     9781 agtttactta caagaccata taatattatt atcttaaaaa aaggggacat aataatatgg
     9841 ttttgacagg agcacattat atttacattc tatttatggt aattatatta attactatga
     9901 ttatgaaaaa ggatacaata gtaccatgta tattaggtgt tttttttatg ggattgttct
     9961 ttgaaaaaaa catctttggt gctataacag cagtgtttaa ctcttttatt atatctttaa
    10021 atgagttggg tccaattatc ttgattatag ctattatggt tgcattatct aaagccctag
    10081 aagccaataa tgctatacag tatatggtga gaccattttc gagagttata aaaaattcta
    10141 atacagcatt ttttgtaact ggatttgtta tgttagttct ttcttggttt ttctggccaa
    10201 ctccagctgt tgccttagtt ggagctgtat ttttacctgt tgctatgaga gctgggctac
    10261 cagcaattgg tgttgcagta gcattaaatt tatttggtca tggtcttgcc ttatctacag
    10321 actttgttat tcaaggagct ccaagtataa cagctggtgc agcaggtgtt gcagtatcat
    10381 atgttataaa tgatggtatg attttgtttt gggtgatggg aatcgtaacc atatctatgg
    10441 cattttatac attaaaaaga gatattaaca aaggaatgtt tagagaagaa ctaaaaggtt
    10501 ttgaaagtga agaagtagaa gcgttcaatg gaaaatctaa aatagcaact attttagtag
    10561 ctttgggatt tcttgctgat ataattgcta tgtatgtatt tgacctaaaa ggaggagatg
    10621 catcagctct tttgggtgga acagcagtat ttttaataat aattataaat gttataaatt
    10681 ttggcaaaga tagtcttgaa aatgtatgtg agaatataat tgatggtttt gtgtttggga
    10741 taaaaatatt tggagcaatt ataccaatag cagcattttt ctatatgggt gaagttgcac
    10801 cattgacagg tgtatttgga aaagtattag caccaggttc acaaggttta ttatcagata
    10861 taggcatagc tctttctcaa acaataccac ttaataaatt tgccgtatca ggtatagaaa
    10921 ctgtagtggg agcaataact gggcttgatg gttctggatt ttctgggatt tcattagttg
    10981 gttcacttgc ctctgtattt ggaactgcta taaatgcaag tgttggtgca ttagctgcat
    11041 taggacaaat cagtggtata tgggtaggtg gaggctgtct agttccttgg ggtcttattt
    11101 cagcagcggc aatttgtggg gttagtccaa tagaattggc aaagcgaaac tttgtcccag
    11161 ttataaccgg attggttgta acaaccatag tagcaatgtt tattatttaa taaatcgaat
    11221 aaatctttaa ttgtataaat taaaaataga tgtgtagcta taatttatta taattgtttt
    11281 actaattcta agccatacat ctatttttat tgatattttt attagtattc tttaataaag
    11341 taatattttt cattatatta tacataacat ctaaatataa catctaaaat actgttatct
    11401 atatttaata tcttgccaaa ttttttgatg ttttattgcc ctgtcccacc aacatatata
    11461 agctatcaca agtttttacc tatactatca ccaaacaaaa attctaattt taatttatta
    11521 ttttataacc tatattatat taactatatt agtttgtaga ctttagatgt aattataaat
    11581 attaatactc caagagttca aattcatatc ctagttttct tgcatttgat ataaaatcat
    11641 ttaaaatttc tgtactagtt ttggaaactg catgtagtaa caagatagaa ccatcatgta
    11701 gattatccat tattttttgc gttgcttctt catgtgatgg ttgtttatca gtatcccagt
    11761 ctctgtatgc aaaactccaa aatacagtct tgtatcctaa atttttagtc attgccaagc
    11821 ttttttctga gtattttccc ataggaggtc taaaaaattt aaccatatct ttcccagtta
    11881 catctttata taacttttca acatcatata attcgtcatt aaagtttttt agattgcttg
    11941 tttttgttgg catagatgga tgggttttac tatgatttcc aactatatgt ccctcagaaa
    12001 ccattctttt tactaaatct ttattttctt ttatatatgg agctgtaaca aaaaaaactg
    12061 ctttaacctg gttttgtttt agagtgtcga gtatttttgt agtgtatcca ttttcataac
    12121 cttcatcaaa tgtaagatat agtgtttttt gaccatcttt tgtaggtcca ttgtataggg
    12181 catcatagtc agaaaattta aattcaatgt ccgtatttac ttctggtgtt ttatgcttat
    12241 tgtttggtat ataaaaccaa tcaagagtag tgttatctaa agaagataca tctaatttat
    12301 tattatcatt attagtagtg gcttttgatg gtttatctgt tccgtctgaa actattacat
    12361 tggaagtatc tttaccacta tctatttttt ccttatcttc ttgtaactgt gtttccttat
    12421 tttgattttc gttttgattg ttttgtgaat ttgaacatcc aacaataaaa aaaatagaaa
    12481 tagaaagtag tgttaaataa tgcaatactt ttctaaacat tttgaagctc ctttctaaat
    12541 taataataat tgcatataat aataattata tgattaatta caattgcata tagtattatt
    12601 ataattggaa attactatta ataatagtta tatctttaaa aataaagtca caatagtatg
    12661 acaaagggtg aataatcaat aaatttaaaa aaaaatgaaa aaaatagttg accatattat
    12721 gagaagatgt tattataata aatgtgctca acaagaagta acaaaataac aagcacaaag
    12781 aagttaattg aat
//
LOCUS       DAEPXW010000103        12603 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.105, whole genome shotgun sequence.
ACCESSION   DAEPXW010000103 DAEPXW010000000
VERSION     DAEPXW010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12603
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.105"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            77..919
                     /locus_tag="KRM55_003020"
     CDS             77..919
                     /locus_tag="KRM55_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH1595234.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            934..1398
                     /locus_tag="KRM55_003021"
     CDS             934..1398
                     /locus_tag="KRM55_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595235.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            1385..2557
                     /locus_tag="KRM55_003022"
     CDS             1385..2557
                     /locus_tag="KRM55_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1595236.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIVLKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            2601..3536
                     /locus_tag="KRM55_003023"
     CDS             2601..3536
                     /locus_tag="KRM55_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBH1595237.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(3907..4632)
                     /locus_tag="KRM55_003024"
     CDS             complement(3907..4632)
                     /locus_tag="KRM55_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1595238.1"
                     /translation="MLESKIRTPEEIKRYMLDLKKWLAQERSKPVEEMSDFFSKRIDI
                     YDNVHLANWTEEYAHIADYFDTPLSSLLDIGCGTGLELASIYRKFPNVQITGIDLSKE
                     MMSKLKEKYSDKNIDLILADYFEYPFEQEKYDAALSFETLHHFKYQKKQKIYKKLFQT
                     IKPGGYYVECDYIACCLEEETICLEQYEFKCKENHVPDDVFVHIDIPLTIEHQIHLMK
                     NAGFRAVYVLHENNGTMIIKAEK"
     gene            complement(4650..5216)
                     /locus_tag="KRM55_003025"
     CDS             complement(4650..5216)
                     /locus_tag="KRM55_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595239.1"
                     /translation="MPPKPIITKQDIINAAIQLVRENGISSVNARNLAKTLNCSTKPL
                     FRIYTNMDEIKEDIKIELDNYYNSFMESKINDENRLLSQGLAYIEFAQNEKMIFNTLF
                     MNMTMNGSSLQDIIHAKWNRITIENAKKVTGLSIEKSEMLFINFWLYSHGVATQIISN
                     GIDIPLDMVQQLLENAFERFSLDITKTE"
     gene            complement(5609..8302)
                     /locus_tag="KRM55_003026"
     CDS             complement(5609..8302)
                     /locus_tag="KRM55_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH1595240.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVEPEVAYVVTDMLESVITEGTGGVAALPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            8516..9214
                     /gene="yunB"
                     /locus_tag="KRM55_003027"
     CDS             8516..9214
                     /gene="yunB"
                     /locus_tag="KRM55_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBH1595241.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            9372..9989
                     /locus_tag="KRM55_003028"
     CDS             9372..9989
                     /locus_tag="KRM55_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBH1595242.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(10146..10598)
                     /locus_tag="KRM55_003029"
     CDS             complement(10146..10598)
                     /locus_tag="KRM55_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HBH1595243.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            11046..12404
                     /locus_tag="KRM55_003030"
     CDS             11046..12404
                     /locus_tag="KRM55_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1595244.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
BASE COUNT         4471 a         1675 c         2139 g         4318 t
ORIGIN      
        1 caatgatagg ttatataata aaatcactaa caattatatt ataagaaaat tataaaaatt
       61 acaaggaggt atagaaatga aagaaaaagc agggattaga aatgccataa tagcagcctt
      121 tataatcaca atattggcag aattaattgg acctatttca tttaaagtta tgggaattaa
      181 tgtaacttta cttagtatac tatgggctat attcatagga atggctgttt ctcctcattt
      241 attagggaga gttataccag ccttaaaaaa gtttataggg gataatgaaa taaatgtatc
      301 tccatattta ttatctttga cactatatcc attagggata atgtttggaa ttaatgcagg
      361 gcctaaagtt ggtatattac ttcaagcagg accagcactt ttattacaag aatttggtca
      421 tatgggtaca atgttgatag cattacctgt tggagtagca ttgggtcttg gaagaagtgc
      481 attaggtggt actttttcat tatgtcgtga cacagcacta ggaattattg gagataagta
      541 tggattaaac tcaccagaag gtataggaac actaggaact tacataagtg gtagtatatt
      601 tggaacatta ttattttcat ttttagcacc agtgggtgta cttttaggat ttcatccata
      661 tgctttagca atggcatcag gaatgggtag tggttcaatg atgggagctg caacagcatc
      721 attaatgaat acggttccac aaatgtcaga gcagatttta gcatattcag ctactagtgg
      781 attgattaca gctgttactg gaatatatat agaattattc ttatctttac cagtagccaa
      841 ctactattat agcaaagtag ctccagttat tgaaagattt agaggaagaa aaacaagaag
      901 aacaagtaat aaattgtaaa ggaggatata tatatggaaa aaacttttaa gactattatg
      961 gagcagataa aaatagtatt gtttatatat attattattt gctttggaca aatgatagca
     1021 cttaagactc aggctcaaga tttgttgatt ggaagtgtat ctggattttt gttggtgata
     1081 attgctatta taataaagaa ttttgttaaa aaacctaatt taccaggttt tgcatgggct
     1141 acattagttg cattcgtttt atcgcttcca atatctccag tgggggatat catagcaaca
     1201 aatgtaggga aaatcaattt tatgtctaca gtaacaccat tattagcttt tgcaggaatc
     1261 tctgtaggta accaattaga tatattaaag actttgagtt ggaagttagt agttatatca
     1321 tttatagtta tgacatctac ttactttggt tctgctttta tatctcaaac agttttaaga
     1381 ttaaatggaa tgctttaagg aggtagtaaa tatgaatgaa ttaaaagcaa aaattaaaga
     1441 ggaaataaag ttattatctg aagagaaaaa gacatcattt gaaaaagttt ctgactattt
     1501 attttcaaat ccagaattag catttgagga gtataagtca caaaaagcat tatgtgattt
     1561 gttagaagaa aatgaattta atgtaactaa aggtgtagga ggattagaaa catcttttga
     1621 agctgtgtat tcaaatggaa ctaatgggaa aacagttgct tttttagctg aatatgatgc
     1681 acttccagga atgggacatg catgtgggca caatatcata gggacaagtt ctgttggtgc
     1741 aggtattgta ttaaaagaaa tcatgaaaaa acataatata gaagggactg taaaggtttt
     1801 tggaacacct gcagaagaaa gagtaggtgg aaaaataact atgattaaag aaggtgtatt
     1861 taataatgta gatgctgcat taattttaca tccaagtgat gcttcaatgc ctgatgatat
     1921 atcatttgct caagttaatt taaaatttga ttttactggt aaggcatcac atgctgctgc
     1981 ttttccttgg gaagggaaaa gtgccttaag tggagtaata gcactattta acagtgtaaa
     2041 tagcatgaga ttacatctta aagattatgc aagagtacat ggaattataa ctgatggagg
     2101 tagcatacat aatataattc ctgaaaaatc tacagctata tttaatgtaa gagctttaag
     2161 catagaatat ttaaatgaga tttgtgaaat gcttaaaaat tgtgctaaag gagctgcaat
     2221 ttctactgga actaatgtag aaatagttca attagatgaa atatacaaag agattaagaa
     2281 tgattctgaa ttagtgaata tagttagaca aaattttgaa gttttgggtg aagactatgt
     2341 tgaaagagat ttaagtcaag gtataggttc aactgataca ggaaatttaa ctcatgagat
     2401 acctgcaata caagcatata taaaattaaa agaaaatact gcaactcata cagatgaatt
     2461 tgctgttgca gctggtggtg aagaaggcag agtagcactt ataaaagcaa ttaaggtgtt
     2521 agcaatgtgt ggagtagata ttttgtatag taaataatat ataattttaa aatatattaa
     2581 gaaaggaaat cggattagac atgatattaa aacaagtaat agaggtttat gacattttag
     2641 ataaagcaaa tgctaatggg gaagaagtaa aaacttactt acaaggttat ggtgaagtag
     2701 atgtaactgt aaaagaattg tcttcaagta aaggttcaac agatttagtg aagcttacaa
     2761 ttcctggaaa aaatggaaaa ttaaaaggtg gagatgctcc tactcttggt attttaggta
     2821 gactaggagg gattggagca agaccagaag ttataggttt tgtctcagat ggtgatggag
     2881 cattggtagc aattgcagtg gctgctaaac ttttggatat gcaacgaaaa ggggacatat
     2941 tagatggtga tgttgtaatt tcaactcata tttgcccaga tgctccaact aaagaacact
     3001 atcctactcc ttttatggat tctccaattg atatgatgac tatgaatgaa aatgaagttg
     3061 atagtagttg tgatgcaata ctttctatag atactactaa aggaaataga gtaatcaata
     3121 ctagaggatt tgcaatatcg ccaactgtta aagaaggcta catattaaaa actagtgata
     3181 accttttaga tattatgcag actgtaacag ggaaatctcc atttgtattc cctttgtcta
     3241 ttcaagatat aacaccatat ggaaataatc tgtatcactt aaatagtatt ttacaaccag
     3301 cagtagctac agatgcacca atagtaggag tagcaattac aacagagatg cctgttgctg
     3361 gatgtgctac aggtgcaact aattttagtg atttagattc agctgggaga tttgcaattg
     3421 aagttgccaa gctatttggt agaaataagt gtgatttcta tgataaagaa gagtgggaaa
     3481 tgcttattaa gagatatggc aaattaaata gatttcaaac atttggtata cagtaattag
     3541 aaaaatatta agtttatata atttgtgata taaatatcta tactatgtaa acaactagaa
     3601 acaaaagata tagtttaaga cttaaaaaat aaaatattta tttgattaca taaataagga
     3661 gtgttctatt taggtaagcg ccaataagta gtataacatt aaagctaacc taattgttga
     3721 tatacaagat tgaaatgaaa acagtgcgta ttataagaaa aggttacgca ctgttttttt
     3781 cgtcctgtta tatagcagaa cactagtttt taagggtatg agtataaaac ttttttaaat
     3841 ttcatatcta cgaattttgt agattgtcca taagcgatat gcaataatta ggaaaatatt
     3901 ttgagtttat ttttcagctt taataatcat tgtgccgttg ttttcatgaa gtacatacac
     3961 agctctaaag cctgcatttt tcattaagtg tatttgatgt tcaatagtca aaggaatatc
     4021 aatatggaca aaaacatcat caggcacatg attttcttta catttaaatt catattgttc
     4081 aagacaaatt gtttcttcct ctaaacaaca ggcaatataa tcgcactcaa cataatatcc
     4141 tccaggttta attgtttgaa aaagcttttt atatatcttc tgctttttct gatatttgaa
     4201 atgatgaagc gtttcaaatg agagggcagc atcatatttc tcttgctcaa aaggatattc
     4261 aaaataatct gccaagatta aatcaatatt tttatctgaa tatttttctt taagcttact
     4321 catcatttct tttgataaat caatgcctgt aatttgtaca ttaggaaatt ttcgataaat
     4381 cgatgcaagt tctagaccag taccacaacc aatatcaagt aaagaagata gtggagtatc
     4441 aaaataatct gctatatgtg catattcttc tgtccaatta gcaagatgaa cattatcata
     4501 aatatcaatt cgctttgaaa agaaatccga catttcttca accggtttac ttctttcttg
     4561 cgctaaccat tttttgaggt caagcatata tcttttgatt tcttcaggtg ttcttatttt
     4621 actttccaac atataaaaca gtcctttctt tattcggtct ttgttatatc caatgaaaat
     4681 cgctcaaaag cattttcaag taactgttgt accatatcta atggaatgtc tatgccattg
     4741 gaaataattt gtgtagctac tccatgagaa taaagccaaa agttaataaa tagcatttct
     4801 gatttttcta tagataagcc tgtaactttt ttagcatttt ctatagtaat tctgttccat
     4861 tttgcatgaa taatatcttg taaggatgaa ccattcattg tcatattcat aaataaggta
     4921 ttgaaaatca ttttttcatt ttgagcaaat tcaatgtatg caagtccttg acttaacaga
     4981 cgattttcat catttatttt actttccata aaagaattat agtaattgtc tagttctatt
     5041 ttaatatctt cttttatctc atccatattt gtgtaaatac gaaaaagggg ttttgtagag
     5101 caattaaggg tttttgctaa gttacgagca tttacgctac ttattccatt ttctcttacc
     5161 aactgaattg cagcgttaat aatatcttgt tttgtaataa tcggttttgg tggcatcttt
     5221 tcatcctcct ttcggtaact taagttgcgt aactggtgtt gttattataa caaagacata
     5281 taactgtgtc aatagacttc aaagaaaagc tacagacatc gagtgtaata tgatttattt
     5341 caataaatac cataatatgt gtacttatat cttaaaaagg agataaacag taaaatgtag
     5401 tttagttaaa tttgaaactt cgtcaaagct tctttgtacg ataagacaac gtacaaatca
     5461 ttgtatgggt aacagagaaa gaactgcgtt gattgaggat gaaatctcac atgatacgtt
     5521 gtaattataa aaaaaggagc gtttcaaagt gattttttta atcaccttga gacaactcct
     5581 tatattttta tttaaattct attttttatt aagttgctgg agttccacca ccatcaggag
     5641 gagtagtaga gccaccacca ttatttccac cattatcagg aggagtagta gagccaccac
     5701 cattgtttcc gccattatca ggaggagtag tagagccacc accattattt ccgccattat
     5761 caggaggagt agtagagcca ccaccattgt ttccgccatt atcaggagga gtagaaccgc
     5821 caccattatc acctgtgtta ttattgttat tattattttc ttctggttgg ttattgtctg
     5881 gtttttttgt atcttcagat gatggttgag aacttacttt agtaggagca gtaccttcaa
     5941 taaatgctgc tttagagcca gaagattgct ttcctccatc ctctaaatta atttttgtaa
     6001 aatatacatt tttaggaact tcaaattcag taaccgttaa attagcatgt attttttcca
     6061 taattttttc ccataatttt gcagtgctag tacttccatg tggtacttct ctacgtttta
     6121 tagtgttacc agaatcatct tttctaccag catcatctcc aatataagtt gcaccaacat
     6181 aataaggagt gtaaccgaca aaccaagcat catatgcact atttgtagta cctgttttac
     6241 ctgctacagg cattcccttt ggaagtgcag caacaccacc agtaccttca gtaattacac
     6301 tttctaacat atctgtaacg acataagcta cttcgggttc tacaacttta tgttcctcag
     6361 gagcattttt aactaataat tgaccatcaa aggtagttat agtagtaaaa atagaaggtt
     6421 ctacataaat accgtgattt gccaatgtac cataagcagc agccatttga agtggagtaa
     6481 taccattcgc cataccacct agtgtcaatg atgggaattt tctatcactt gcttcagatg
     6541 aacctgagtg attattcttt aaagttgtta taccaaagtt ctttaagtaa tccatcatta
     6601 tatctacaca ttcatcataa gagtctccaa gcatttcagc agttttgaca gctatcgtgt
     6661 ttgaagattt agcaagtgct ttacgtaaac tcatagaacc atgaccagca gtagtggttc
     6721 ttggattcca tttattattt tcttcaaact tatatcctcc tcgagaatca cttagagcag
     6781 ttgcttgtgt tatttttaga gtatcaatag ctggcgtata tattgctaaa ggttttatag
     6841 aagaacctgg ctgatgaggg ttagtagcac gatttaaagt ttttctacca cttatatttc
     6901 ttcctccagc tagtgctctt atttcaccat ttttataatc taagattacc attgcagctt
     6961 gcggttggct aactccatca ggaccgacca tatgtcctgg gaaattgcta tttctatcaa
     7021 attcttcttc taaagcatct tgcattttag ggtctatagt tgtgtttaca attagaccac
     7081 cattgtagaa taagttttga gcttcatcat ttgtatgtcc ttgttccatt aaagcattta
     7141 taacttcact ttcgataagg tcttctacag atgaagaaac tttatctgat gattgaggca
     7201 attttatttc tattttagct ttgattgctt catcatattc actttgtttt atatatttca
     7261 attctaacat tttctttaaa acaatttctt gtcttttttt agcttcagga ttacttacag
     7321 cctttctaac aactaatgta cctgctttta attgtctata agtatcatta gatataagct
     7381 cccaagattt tattttttca atcatatcaa agtccacttg agtagggtca tctaaatcat
     7441 catcagttgt gttaacaaaa aataataatt tattctctaa atcctcctta gtttcatttc
     7501 cctctaactt agaagtttta taggctgaaa atcttgatgg atttttagtt gaaccagcaa
     7561 gaagtgctga ctctgctaga gtaaggtcag ctgcagactt atcaaaataa ccacgtgcac
     7621 cagcctcagc acctgctaga cctctaccaa cgaagaagtt atttaaataa gtttctagta
     7681 ttttatcttt acttactgtt ttactcatct catgtgcata gtaaatatcc tttattttac
     7741 gaggtatagt ttgctgttca gttgttaaca gcattttgga tacctgcata ggaatagtac
     7801 taccaccttg cttagtacct gtaagggtct ttaatactga cctaaataaa cctttaatat
     7861 cgacaccctt atgctcataa aaacgctcat cttctattgc aattacagca tgttgaagat
     7921 aaggggaaat cttatctaat ggaacgggtg tctttttatt tacacttgga gctgtagata
     7981 atgtttttcc attagcgtat ttaatagtag ttgtttggtt cgtctgttta tctaaaacag
     8041 cttctgtaac tggagttaca tctcttagtg acgcaaatac tagaccagca gtacctgctg
     8101 taccaacaac tagtaaaact aaaaatacta tcccaaatac tcttagtttt ttaaatttat
     8161 cgcttttttt agattttttc ttgttttttg ttgaacgagt cttgttagct gaagttctat
     8221 taattggttt atttgtatta ccagatgagc taactttttt tctcctgatt ttatttccat
     8281 ttttatcatt atcgttattc ataagatttt aacctcctta cttaatgcaa tattataaca
     8341 caaataggag tagttttgta attaatagaa aaaatgaatt tgctataata ttctgtacat
     8401 tgtatatgta taaacgtaat atattaaaaa gtctatattt ttattttatt tatttttgac
     8461 aaatattata aaaattatgc caaagctaca tataaataaa taggagggga taattttgaa
     8521 tagaatagta gatagaaaaa caaaaaatga atttagaaaa atcatagcta tttttttagt
     8581 aattcttttc ttgtctgtat ttataggcag ttttatatat atagataaaa ctttaagacc
     8641 gacaataaca gttttagcag agactaaagc tcttgaacta gcaaataggt cgataaataa
     8701 agctgttgct gagatggtag aaggaaaaat aaattatgaa gatttaatgg atatacaact
     8761 tgataataat ggtaaaataa ctatgataca agcaaacact ataatgatga atgaaattgc
     8821 atctgcaata gctttagaaa tacaagatga attaaaaaag gataagacag caagttctta
     8881 catacctata ggaacagcat taggaagtcc tatattagct aaatacggtc ctaaacttga
     8941 agtatctatt gaacctatag gaacagtatc agtaaacttt aaaacggaat ttgagtcttc
     9001 aggtataaat caaactagac atagaatata tttagaagct caaacgcaag ttaaagtagt
     9061 aataccactt ataacttcaa caaaacaaat taaagctcaa atacctattt gtgaaactat
     9121 aatagtaggt gatgttccag aaagttatgt aaatattcca gaaaaaaatc taggaaatgt
     9181 tttacctaac actggaaaga ataccaacaa gtaatataaa gttgtatatt ttttaaggat
     9241 ataaagtaaa aaaacataca atatcaagaa aaaaagatat tgggtattta aagtaatact
     9301 ttatttaatt ttaagtaaat cgggtatcta catatataga tactaatttc aaagaatagg
     9361 agggtgttta tatggaaata ttcgcaatag gacattcaaa ttatccatat gataagctta
     9421 ttaatatgat aaaaaaatat gacataaatt gtgtagttga cattagagaa actccatatt
     9481 ctaaatataa tattcaatac aataaagagg catttaacga atctcttaga aattccggat
     9541 ttttatatat atacatggga aaagaatttg gagctaaaag aactaataaa gatgtatata
     9601 cgcaagaagg ttatgcagat tttgagaaag tagcaaaaga agatattttt ttaaacggaa
     9661 tagaaagatt aaaaaagggt tgtcaaatgg gttataggat agttttatta ggagctatgc
     9721 aagaacctat aagatgtcat agaagtatct tggtgggaaa agtattaaat aaagaaggtt
     9781 ttgatgtaaa atatataatg catgaaggaa atttggcata tcaggaagat atagaggaat
     9841 cattattgga taagtatttt agtgatagaa agcaactgag tattgacaat ttattaggga
     9901 gtgcattaac gagagaagaa atgatacaag aaggttataa gctagctaat aaagaaatag
     9961 gatatagaac tgagaaacta ggtaaataaa aatatacaag tagataaaat acagtactta
    10021 tcttaagtaa aataatatta tgaatttata atagctaggc atgatgtgcc aattaaaaat
    10081 attctagtta tttaataata tcattaaatt tagggtattt tttaatagca catcatgttg
    10141 cagttttaaa aaataaaatc tctaatattg ccataatcaa ctgttctatt aagagtagga
    10201 tgactagata taaacctaac tgtaattttt gaatttaaca aacaaggatt tgaaattaaa
    10261 aatactctat ctccattgac aatagaagta atagctactg gcaaaatatc tacaaatgta
    10321 tcatatctgt ttttagcaat ttgataagga taatttccta caaaaacaaa tagatttaaa
    10381 tcatatatat tatcagtaaa ccaagcccat tgaccataaa ctttgtcgat attcattgtg
    10441 cctaaaccaa gtgtatcaaa gtatgttgct atagttaaat aaatattttc catgttttct
    10501 aaatatgaaa cagtatatct tctgaaacgt atgggtgctg tggaagaaat aggataaacc
    10561 atatttacat ttagattatt tgcatttaaa ttaaccaaag tatcacatcc taaaattagt
    10621 ctataaaata caatatttaa atggatgcga ttttgttaca tctaaagtgt aatattttat
    10681 atattgaaaa agtggtaaaa gtttggatga ttaaataata ttataaaaaa aatataaaat
    10741 gtacttattg ttattgctac acgatagtga tacaatatta acgaaatata gctactttta
    10801 ataataacgg aaaatattta tattaaatta ataaatattt taaatgtggt atccataaaa
    10861 aataataaac ataagataat tataaagata tactgtgttc aaatgatatt aaacaagatt
    10921 tatattattt gaaagcagta tattataatg cgaacaatac aattctaaac tttgcattgt
    10981 caatttacag ttcgataaac taattaaaaa ttaaatttat ataaagaggg aaaagaggaa
    11041 tagggatgtt tataaggaaa aatgttataa agttagcaat tcctataatg atagagcaga
    11101 cgtttgtcat gcttttagga gtatttaata caatgatggc aggtcatatt ggggaagaag
    11161 ctgtatctgc agttggaatg gttgattcaa taaacaatat atttatatct gtatttgctg
    11221 cactatctgt tggagctact gttgttgtag ctcaacaaat aggaaaaaaa gatagtgaaa
    11281 aggtgaatga aactattaag caggctctag tgtctggagt aatattatcc tttacaataa
    11341 caatattgat gtgggttttt agaactggtg taattaattt attttatggt tccgcagaag
    11401 aattggtaaa atcaaatgca aaattataca tagagtttac attatttacg tatccattta
    11461 ttgcgacaca acaaatagca aatggtattt taagagggtg tggagatgta aagaaaccta
    11521 tgtatgtgac tatgtttatg aatatagtaa atgtaacatt aggatatata cttatatatg
    11581 gtattgattt aaatcctcta ggaataaatt tgcaaacacc atcctatggc ataacaggtg
    11641 cagctatatc tattgctata gctagaataa ttggatgtat agtaattata agagctttat
    11701 ttaaaggaaa cgaatttata tctatgggta aaatatttcc atttaagatt gatgttgaaa
    11761 ctcaaaagtc tatatttaat ataggaatac cagctggagt tgaacaacta ctttttaatg
    11821 caggtaaatt gattgttcaa gtatttatag ttactatggg aacatcagca attgcatcca
    11881 atgcaatagg aatgtcaatt gcatccataa taaatgtaat tgggaatgct ttagctttgt
    11941 ctgctacaac cttggtggga cagtatatag gacgtggaga tattaaagga gctaagagta
    12001 ctttattata tttaactaaa tttgcaacaa tttgtttatt tatagtagga gctatattta
    12061 taccaattgc accttggatt tcaagtatgt atactcaaaa tgctagtgta attgacatct
    12121 caacacaatt aattcgaagt gattgtttag ctatggtaat atggcctata tcctttgtat
    12181 tatcagcagg gctaaaggga gccggtgata ctagatatac aatgatgact gcagtaatag
    12241 gtatgtggat ttttagaatt tttacaggtt acgtattggg ggttgtatta gaatttggag
    12301 tgttaggaat ttggataggt atgtatactg attggcttgt tagagggact ttatattgtt
    12361 taagattaag aggaacaaag tggctaaaac acaaagttgc atagaatata tgaaatcact
    12421 tttagatgga taactctatt tagaagtgat tttttatgta gttattatca taattataag
    12481 tatgatatat aaggtgatta aattacataa ataaaggcta taatagtatg gatattataa
    12541 attatatatt gagcagaatt acataatttg gcgataaata ttagaaatat atatctatag
    12601 aaa
//
LOCUS       DAEPXW010000104        12418 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.107, whole genome shotgun sequence.
ACCESSION   DAEPXW010000104 DAEPXW010000000
VERSION     DAEPXW010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12418
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.107"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            241..705
                     /locus_tag="KRM55_003031"
     CDS             241..705
                     /locus_tag="KRM55_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBH1595245.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            712..1206
                     /locus_tag="KRM55_003032"
     CDS             712..1206
                     /locus_tag="KRM55_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBH1595246.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNVFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            1222..2247
                     /locus_tag="KRM55_003033"
     CDS             1222..2247
                     /locus_tag="KRM55_003033"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBH1595247.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            2234..4681
                     /locus_tag="KRM55_003034"
     CDS             2234..4681
                     /locus_tag="KRM55_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBH1595248.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGNGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            4861..6234
                     /gene="radA"
                     /locus_tag="KRM55_003035"
     CDS             4861..6234
                     /gene="radA"
                     /locus_tag="KRM55_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBH1595249.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            6237..7307
                     /gene="disA"
                     /locus_tag="KRM55_003036"
     CDS             6237..7307
                     /gene="disA"
                     /locus_tag="KRM55_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBH1595250.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            7396..8490
                     /locus_tag="KRM55_003037"
     CDS             7396..8490
                     /locus_tag="KRM55_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBH1595251.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            8619..10796
                     /locus_tag="KRM55_003038"
     CDS             8619..10796
                     /locus_tag="KRM55_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595252.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVLFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(10982..11752)
                     /locus_tag="KRM55_003039"
                     /pseudo
     CDS             complement(10982..11752)
                     /locus_tag="KRM55_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(11861..>12418)
                     /locus_tag="KRM55_003040"
     CDS             complement(11861..>12418)
                     /locus_tag="KRM55_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1595253.1"
                     /translation="IKEFCISSCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRN
                     KARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDV
                     SWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNE
                     THDRDINASINILKEGLRLITIQNK"
BASE COUNT         5066 a         1323 c         2186 g         3843 t
ORIGIN      
        1 aggtatattt aaaatataaa gtatttaaag ttctgaaatc taatcatgaa gcaaaaaatt
       61 agcatttggt tatcaataaa tataataaat aaaaactcat aattaatgaa agaataaatt
      121 catatctaaa tttctataaa aaatttaaat ttatacaatt tagggcttta aaaatttaaa
      181 taataggtgt aaaataatag tcaaagaaag tcaaaaataa aaaggtgtgt ggtgatatta
      241 atggcaacta tgacagatat aattgaaaaa tttattaaag atttgatgga agaagataat
      301 agcatacaaa ttcaaagaaa tgaactagca aacttgttta gttgtgcacc atcacaaata
      361 aattatgtct taacaacaag atttacaata gatagaggat attacattga aagtaaaaaa
      421 ggtggcggag gatatgttca aatagaaaaa atacgaaaaa gtaaagatgg gcatattaga
      481 gaactactaa atgaaaaaat aggaagtcag atatcctata aaaaagcaaa agaattatta
      541 gaaggtttaa aagagtcgga tttgattaac gaaagagaat taaaattaat attatatgca
      601 atagatgata aatcattgtg tatgccaata tatgaattaa aagagaaggt aaggtctaat
      661 attttaaaga atataataat aggattattt agtatagagg agtgataatt tatgctatgt
      721 caaaaatgca ataagaataa agcatctgta tattataata agatagtcaa tggagaaaaa
      781 acagagatgt atttatgtag tgagtgtgca aaagagaata cagaaatgaa ttttaactta
      841 gatatgcctt tttcaatgat ggatatattt tctaatttag gttttcaacc taaaaaagaa
      901 cttgaggaaa agctagtttg tcctaaatgc aatacaacat atagtgagtt taagaataat
      961 gggagatttg gatgtagtga atgttataat gtatttagta gtcaagtaaa tccaatgctt
     1021 caaaatatac atgggcatat agaacataca ggaaaagcac ctaaaaaatc tttttataag
     1081 ataagtgtag aaaatgagat taaagaacta aaagaagatt tagatagagc tataaaaaat
     1141 gaagagtatg aattagcagc tcaatttaga gataaaatta aatatttaaa aggttctatt
     1201 gactaagatt ggagtgatat tatgaaagag aacatagtca tgaaatcaag agttaggcta
     1261 gctagaaatt taaataacta tccatttcca aataaattag ataaagaatg tgccatggaa
     1321 ataatagaaa aagtaaaaaa tgcgtttatt aattctaact tagaacaaaa agaagaattt
     1381 gatttctata aaattgaaga tttagaccaa tctaaaaaaa tgcttatggt tgaagaacat
     1441 ataataagcc cagatttagc agaaaatgat aaaagtgcag ttatagtaaa aaaagataaa
     1501 actataagta taatgataaa tgaagaagac catataagga tacaaactat atgtgatgat
     1561 ttaaacttag aatatgcata tagtgtagca aatgaaatag atgatttgtt agaatcaagt
     1621 ttagaatatg cctttaacac aaagctaggt tatctaacat cttgtccaac taatacagga
     1681 acaggaatga gagcttctgt aatgatgcat ttaccagcat taagtcaact aggctatatg
     1741 gatgaacttt ataaaatttc atcacaaata ggtatagcaa ttagagggat atatggagaa
     1801 cgaacagaag cattgggaaa tatatatcaa atatctaatc aacttacact tggaagaaca
     1861 gagtctaata ttatagaaaa tgtaagtgga cttacaaaag atgcaatttc aaaagaaata
     1921 aaagctagag aaatattgca aaaaaaatta ggtataaaac tagaagataa aatatttaga
     1981 tcgataggga cacttgaaaa ttcaagagta atgagtagcg cagaggcaat gagccatcta
     2041 tcaaatataa aaatgggaat agaaatgaac tatatagata aactagattt aagggctata
     2101 gaacaactta tgataggtat acaaccagcg catcagtcaa taatgtataa gagtgatgat
     2161 gttgagaata gagatataaa tagagcaaca tatattagag aaactttgga aaaattaaga
     2221 ggagggatga attgtgaact tcaatagatt tacacaaaga gctaaaaagg caattgattt
     2281 agcgtttgaa tctgctaaaa gtctaggaca caatattgtc ggaagtgaac atatactttt
     2341 aggtctttta agagaagaag aaggtatagc tgctaaagtt ctaagtaaag ttggatttac
     2401 agaagcttat ttagaaggca aaatagttga tatggaaggt aatggagaag aaatctcaga
     2461 agatatagta ttaagtccaa gaagtaaaca aatacttgaa ttatcaggaa tgtttgcaaa
     2521 taaattaaaa acaaattata ttgggactga gcatatatta ttagcaatta ttcaagaagg
     2581 tgaaggaata gctaataaga ttttaaatta tgctggagta aatgatagga ctttagccca
     2641 attaacaatt gatatgatgg gtattagtga taaaaatcaa tacaaagcag aaaatagtta
     2701 cacgggcaac cagaatcaag cagaatctaa agtacttgat aagtatggaa gaaatcttac
     2761 actatatgca aaacagaata aaatagaccc tgtaataggt agagaaaaag aaatacaaag
     2821 agtaatacaa atattaagta gaagaactaa aaacaatcca gtgttgatag gagacccagg
     2881 tgtagggaaa acagccatag ctgaaggtct ggctacaaat atagccttag gaaatgttcc
     2941 agaaacacta aaaaacaaaa ctttatactc tttagagatg ggttcattat tggctggggc
     3001 taagtataga ggagaatttg aagaaagaat taaagaagtt gtagatgaag ttgttaaaaa
     3061 tggaaacata atcttattta tagatgagat gcacacaata ataggggctg ggtctactgg
     3121 agaaggctct atagatgctt caaatatatt aaagccagcc ttagcaagag gagaaataca
     3181 agttataggt gcaactacaa ttgatgaata tagaaagcat gttgaaaaag attctgctct
     3241 agaaagaaga ttccaaccag ttatggtaga tgaaccaact aaagaggact caataaaaat
     3301 attagaagga ttaagagata aatatgaagc tcatcataaa gttaaaataa ctgatgatgc
     3361 tataaaggca gctgtagaat tatcaactag atatatatca gacagatatc tgccagataa
     3421 agctatagac ttgattgatg aagctgcatc aaaagtaaga ttaaaagaaa atacacctcc
     3481 ttcagaaata aaaaaattag aactagaaat agaaaatata gataaagaaa aagaagaagc
     3541 agtaagatgt caagactttg agaaagcagc caaaataaga gatgaacaag gtctacttaa
     3601 aaaacaatta gaagatgtta gagaaagatg gaacaagtca tctaaacatt cagatttagt
     3661 tgatggagaa gttattgctg aagtagtggg cttatggaca ggaataccag ttaataaaat
     3721 tcttgaagaa gaggctgata gacttttgag acttgaggaa atactgcaca atagagttat
     3781 aggtcaagaa caagcagtaa aatctatttc aaaggcaatc agaaggtcaa gagcaggtct
     3841 taaagaccct aatagaccaa ttggttcatt tttattttta ggtccaacag gagtaggtaa
     3901 aacagaatta tctaaggcat tagcagaagt gcaatttgga gatgaaaatc aaataattag
     3961 aatagatatg tctgaatata tggaaaaaca tgctgtgtca agaatgatag gttcacctcc
     4021 aggttatgta ggtcatgatg aaggtggtca attaactgaa aaagtaagaa gaaatccata
     4081 ttcagttata ttatttgatg agatagaaaa agctcatcca gatgtattta atattctgtt
     4141 acaaattcta gatgatggta gactaactga ttcaaaagga agaactgtag attttaagaa
     4201 tactattgta ataatgacat caaatgttgg agcatctaca attggtagac aaaaaacttt
     4261 aggatttagt atagctaaag gagacgaaga agaaaaatct caatatgaaa aaatgaaaga
     4321 aaatataatg ggtgaattaa aacaaagatt cagaccagag tttttaaaca gaatagatga
     4381 tataattgtt ttccactcac taaatgaaaa tcatatatca aaaatagtac ttttaatggc
     4441 agcgaaacta caagagagat taaaagaaat ggatataaaa ttagaaatga gtgatgaggc
     4501 tgttaaatta atttctaaat ctggatttga cttagaatat ggagcaagac ctcttaaaag
     4561 agctttacaa aaagagttgg aagatgagct atctgaagca atcttaaaag gtaatgtgaa
     4621 aaagggaagt aatgtagtag caaaagtcaa agatgaaaaa atagtttttg aaactaaata
     4681 atttaataga gttgcatttt aaaatattgc aaatataagt tttataatct aaacaaaatt
     4741 ttaagggcaa tgaatctata ataattcatt gtccttaatt attttattta atctttacat
     4801 attgtctttc agatatgcta aaattatagt atagaataaa aaattaagga tgataaaagt
     4861 atggcaaaaa taaaaacaaa atatgtatgt caatcttgcg gatatgaaac agctaaatgg
     4921 cttggtaaat gtccagaatg tacaaaatgg aatacatttg tagaagaaat agaccaaaaa
     4981 agcaccaaaa aagaggtctt tataatagat aaatcttcat ctaaaccagt cagtataaac
     5041 tcaatagaaa gtaaagaaga agagcggttt acaacagata taaatgagtt agatagagtg
     5101 cttggaggag gtatagttaa aggctcttta gtgcttgttg gtggtgaccc tggtataggt
     5161 aaatcaacac ttttaatcca agtatctagt aatgttgcca atttaggaaa aactgtttta
     5221 tatataactg gagaagaatc agaatctcaa ataaaaatga gagctaaaag attaggtatt
     5281 aactcagaaa atttatatat atttgctgaa aataatttaa gtataattga atcttattta
     5341 gaaagtgtaa atccagaatt aataattcta gactcaattc aaactgtctt cagtccagaa
     5401 atatcctcgg caccaggaac tgtcagccaa attaaagaag gtacttcaaa attcatgaaa
     5461 atttctaaaa aaatgggaat ttcaacgttc atagttgggc atgttacaaa agaaggttca
     5521 ctagcaggac caaaattatt agagcatatg gttgatactg ttctatattt tgaaggagaa
     5581 agatataata cttatagatt agtaagagct gttaaaaatc gatttggttc aactaatgaa
     5641 cttggagtat ttgaaatgag ggatttagga ttagtagaac ttgataatcc atctaaaatt
     5701 ttaatctctg aaaaaccaaa agatgtagca ggttcagtaa taatatctac tgtagaaggt
     5761 acgagaccaa tgttacttga attgcaagca ttagtttctc ctacaagttt tggtatacca
     5821 aaaagaacat ctacaggagt cgattacaat agagtaggta tgttattagc agtattagaa
     5881 aaacgtgttg gtttgcaaat acaaaatcaa gatgtctata taaacatagt tggaggaata
     5941 aagataaatg aaccctcaat tgatttaggg atagccattt ctgtagcatc tagttttaga
     6001 aatataccga tagatgaaga tatagctgtt acaggagaag tgggacttac aggagaagtt
     6061 agagcagtaa gctttataga aaagagaata gctgagtgta aaaaacttgg atttaaaaag
     6121 atagtagttc ctagaagtaa ttatgatgtt gtaaaagaga ccaaaggcat agaaatatgg
     6181 ccagtagata acttaagaca agctataaat atagtacttg ggaggaatca ataaatatgg
     6241 agaattttct agataataaa aatatgctat atgcattaaa aatgatatct cctggaactc
     6301 cacttagatt aggtctaaac aatgtactaa gagctaagac tggtggatta attgtaattg
     6361 caacaaacga agatgtaatg aaaatagtag atggaggatt tgctataaat gcagaatatt
     6421 caccatcata tctatatgaa ttagctaaaa tggatggagc tatagtttta agtggtgatg
     6481 taaagaaaat attatttgct aatgcacaac ttatacctga ctattttata gaaacatcag
     6541 agacaggaac aagacataga acagcagaaa gagtagcaaa acaaactggt gctatagtca
     6601 taggaatttc acaaagaaga aatgttataa cagtttatag aggaaatgag aagtatgtag
     6661 tcgaagatat atctaagata tttactaagg caaatcaggc tatacaaact ctggaaaaat
     6721 ataagacagt attggaccaa gctgtaacaa atttaaatgc cttagagttt aatgatttgg
     6781 taactattta tgatgttgca ttagtcatgc aaaagatgga aatggtaatg agagttacaa
     6841 gtataattga aaaatatgtg atagaattgg gtgatgaagg aactttagta agtatgcaat
     6901 tagaagaatt aatgggtaca accagaatag accagaaatt aatattcaaa gattataata
     6961 aagaaaacac agaaataaaa gaacttatga aaaaggtcaa aaatttaaat tcagaagaac
     7021 taatagaatt ggtcaatatg gcaaaactat tagggtatag tggtttttca gaaagtatgg
     7081 atatgcctat aaaaacaaga ggttatagga ttcttagcaa aatacataga ctaccaacag
     7141 caataataga aaacttagta aattattttg aaaactttca acaaatttta gatgcatcta
     7201 ttgaagaatt agatgaggtt gaaggaatag gtgaaataag agcaacatat ataaaaaatg
     7261 gactcataaa aatgaaacaa ttagtcttat tagatagaca catatgatga attttaaatg
     7321 aattttacta cttttttctt gaatataata tacactttgg tctataatag ataagtataa
     7381 ctagggggtg aagcattgat aaggaaagta acaagaatat tgtttatttt acttggattt
     7441 acaataggta taacaaccta tttaacatta atgaaagatt ttgaaatatt aacatttgga
     7501 aaagaaacat atggttatat cgcagctgta gtagcaggta taataatagc cattttagga
     7561 tatcttatag aaccatgggt tgtaaataaa gtaaaagaaa ttgctaaaat agtggataaa
     7621 gaattgtcaa aatatcctca gactgatata ttgttagggt ctatgggtct tatagtagga
     7681 tttgttattg cgtatttatt aagtggatta gtaaatagaa taccaatagt aggtggaata
     7741 ctatccttac tattatattt attcctagga tatcttggaa tgaaagttgc gcttaaaagt
     7801 aaaaatgatt tatttaatat tggaaaacta ggaagattag caaatcctat taaggataaa
     7861 gataaggata aagaaaataa aaaagaagta aaagccattc ctccaaaagt attagataca
     7921 agtgtaataa ttgatggaag aatagctgat atttgtaaga ctgggtttat agaaggaaaa
     7981 cttattattc ctgcttttgt tttggaggaa ctaagacata ttgcagattc ttcagatgat
     8041 ttaaaaagag taagaggtag aagaggtctg gatatattaa atataattca gaaagaatta
     8101 aatatagaag ttgaaataag tgagagagac tttgatgata tagcagaagt tgatagtaaa
     8161 ttattaaagc ttgctcaggt tttaaatgga aaagttgtta caaatgatta taacttaaat
     8221 aaagttgctc aattccaagg tgttgaagta ttaaatataa atgagttagc taatgctata
     8281 aaaccagttg ctataccagg tgaagatatg gttgttcaag tggttaaaga aggaaaagag
     8341 gctcaacaag gtgttgcata tctagatgat ggaactatga tagttgttga tggaggaaga
     8401 aaatatatga atgagactat aaaagtactc gttacttctg ttcttcaaac tcctgcaggt
     8461 agaatgatat ttgcaaaacc taaaaattaa tatgttcaaa gaaacctata atttgggctg
     8521 tttattttaa atagatggtc caaatttatt tatttataac gataatgttt aatgtattct
     8581 taaagatggg gatttaaatc agaaagcagg gagaatttat gagaaaaaag attatatctt
     8641 tcttagcaac atttatcata atattaacat cagcaagtca gtatagtttt gcagatgata
     8701 tatcaacacg tggaaaagta atatttatag atatgaatag aactagtatg agtaatatgt
     8761 taagaataaa atcattaaga gaagaactag acaatagagg gtatattggc ttgatgaata
     8821 taagaggcga taaaggaagt gatgatagaa ggtcatatgc tagtatgggt gctggtggta
     8881 gagctaatgt ggctaatgaa gaagatatta attttgaaag ctcgagtaag gatagaaata
     8941 tagtttttga atcagctaca ggaaaaagtg caaaaggtat aaataattta actataaata
     9001 agtctataaa tgaaaattta aactttggag agtatggttc tgtattaggg tcattaggac
     9061 aaagtttatc tgataatgga ttaaaagcat ctgtattggg taattcagat ataattgaaa
     9121 atggtcaact tataaaaaat agaaacttat gtctaactgc aatggatgaa tatggaagaa
     9181 tacctaatgg aaatgtagat actataaata aaaaagactt atctatgcct tatggaatat
     9241 caactgatta tgataaattg attgtagaga ctaaagaagc ttacaaaaat aatgatgtga
     9301 tttttgtgga gcttggagac acatatagat tagatttata taaaccaaat ttaaatgaaa
     9361 aaacatatga gagtatgaaa gataacatag aaaaaaatat agatatatat ttaaaaaata
     9421 tattttctat ggttgaagaa aatgacactg tctacatagc aagtgcattt ccaagtgatt
     9481 tagattataa aaataaaaga agactttcgc caataataaa attaaatgga gaagggaaag
     9541 gtatattatc atcttcaact actagaagag aaggtattgt aacaaattta gatgttgggg
     9601 ttgaaatatt agacaacttt aatataaaaa atcaaaatat ggttggaaga aaatatgaac
     9661 ttattaacag agatgataat aaagaatttt tgatggatga atatcaaaag atagtatcta
     9721 tttcaagcat aaggtctaca atactgaatg gttttgtaag tatagttttc ttgtcatgga
     9781 tagttgctat gattgcaatt ttatttagaa agcatatatc aaaaaattat aaagaaacaa
     9841 cattttttat attaaaggaa cttttaaaaa taggaatagt aatgccactg tcatttatga
     9901 taacaccaat aatgaatttc aaaacaccat tagcaatatc tttaggaata attataataa
     9961 cacttactat atatcttata agtaaagttt taataaagaa cgatttaaaa aacatgctgt
    10021 tttttactgg attaaccata gtaattatgg ttattgatgc tgggtttggc tcatatttaa
    10081 tgaaaagcaa tgttatgagt tatgattgta taattggagc tagatattat ggagtaggaa
    10141 atgagtatca aggtgtggca atcggtagtg caatatttac atttgcaatt ttacttacat
    10201 ataaaaatat accaaagtgg tctataatag ttttttcttt ggttatctta attacaagtg
    10261 catctccaat tatgggagca aatgttggaa gtgctatttc tgaatgtgtt gcatttttac
    10321 tatttatact attgatatat aatgtaaaga tagatttcaa aaaaatcgta ttattaggta
    10381 tagcagtatt atttgtatta ggagtttttg tagcaataga tatgattttg ggaagtaatt
    10441 cacatttagg tatgtttgta aaagaaattt actttaatgg accaggagaa ataatacaaa
    10501 catttagtag aaagatagag atgaatttaa agctagctca aaccagtgca tgggtaaata
    10561 tactgttaac tggaataggt gtaattttag ttcttatgat taatcagatt agatacttta
    10621 agcaactgat ggatgagtat ccaattgtat ttaaaggatt tatagcatca atagcaggat
    10681 gtttagtaac tcttttagtg aatgactctg ggattgtgtc atcagctaca gcctttattt
    10741 atgtaattgt acctatgata acattaagta taaatctcac agcattaaaa gaataagtac
    10801 tgtatgaata atatgtaaat attaatacat taatttaact tctttattta caaaataaag
    10861 aagaaagttt ataaaaaata aattataata aaaaagagtt tacctcaaaa ttgattattc
    10921 taatcaaatt ttaaggtaaa ctttttttat tataaagata aataacatat aacctcatat
    10981 tttaggtaga tttttttctt atatgtttag gagtgcattt aaatttttcc ttaaaaattc
    11041 tgtaaaataa ttttgtatta gtaaatccat gagcttctaa tatactgcat aaggtatcat
    11101 ttgtgttaat taaatcttta taaatatgag aaatacgcac atcatttaaa tactctaagt
    11161 aagtttgtcc catatactgt ttaaattttc tacaaaaata ttctggttgt aagtgtgcta
    11221 ccttagcgat tttgttaata gaaataggca ttttgtaatt aatctttgta tattctaaaa
    11281 ctggctcaaa ttttgacaaa tcaagtactg tttttttcat atttttatta cctacagata
    11341 ttttaaagtt tgtatataat tcaaataaaa gttcaaataa taagcttgta aagagcagat
    11401 tagctgcagg aggagaacta agtttaattt ctctcatgtt ttctaatata agtttaactt
    11461 tacttgaatt ttttttatag ttattgtcat tggcattaac cttaaagtca aaatagcaat
    11521 ttttaaaatc agggatatat ttgtttagaa aagacaatgg tacttgcaat aatatagagg
    11581 tattttgata aatacatcta gttgagtgaa taattccaga attaatgaac atacactcat
    11641 tagcttttaa attataagtg taaccctcca tgttaatttg taaatcacca gaagttatat
    11701 aaattatttc taatgagtta tgccaatgat ttgctacata actaccacta tcctgaacct
    11761 cccatgacta aagtcacagg gttcctgctt cacagaattt tgcatactaa aataaattct
    11821 ccacaggcta tccccgtagt tcctacggtt cttacataag ttatttattt tgaattgtta
    11881 ttagtcttaa tccttctttt aatatattta tacttgcatt tatatctcta tcgtgagttt
    11941 cattacaact aggacaaatc cattctctta tatttaagtc cttcacttcc tcgtttttat
    12001 acccacattt attgcatatt tgtgaacttg caaagaattt acccaccttt acaatttgtc
    12061 taccatgcca attagccttg tattctaatt gacgaataaa ctctgaccat gacacatcag
    12121 aaattaagcg agatagttta cgatttctaa tcatattctt tacttgtaaa tcttctatgc
    12181 aaataatatc attctctttt attaatttag tagatagttt ttgtagaaaa tcatttcttt
    12241 gattagctat atgttcttga agtcttgcaa cttttaatct tgctttattt ctatttaaac
    12301 taccaattgt ttttctcgat aattctcttt gtaatttagc aagtttgttt aatgacttct
    12361 taagatactt aggattttct ataaattctc cacaacttga gatacaaaat tctttaat
//
LOCUS       DAEPXW010000105        12306 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.108, whole genome shotgun sequence.
ACCESSION   DAEPXW010000105 DAEPXW010000000
VERSION     DAEPXW010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12306
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.108"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..321
                     /locus_tag="KRM55_003041"
     CDS             <1..321
                     /locus_tag="KRM55_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1595254.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKS
                     VYKK"
     gene            337..1920
                     /locus_tag="KRM55_003042"
     CDS             337..1920
                     /locus_tag="KRM55_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH1595255.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKNLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1948..3276
                     /gene="ssnA"
                     /locus_tag="KRM55_003043"
     CDS             1948..3276
                     /gene="ssnA"
                     /locus_tag="KRM55_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBH1595256.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYTQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3421..4773
                     /locus_tag="KRM55_003044"
     CDS             3421..4773
                     /locus_tag="KRM55_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH1595257.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            4965..6074
                     /locus_tag="KRM55_003045"
     CDS             4965..6074
                     /locus_tag="KRM55_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1595258.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6357..7748
                     /gene="hydA"
                     /locus_tag="KRM55_003046"
     CDS             6357..7748
                     /gene="hydA"
                     /locus_tag="KRM55_003046"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH1595259.1"
                     /translation="MGIVLKGGKVITSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7742..10303
                     /gene="xdh"
                     /locus_tag="KRM55_003047"
     CDS             7742..10303
                     /gene="xdh"
                     /locus_tag="KRM55_003047"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBH1595260.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTTDALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10455..11801
                     /gene="rpoN"
                     /locus_tag="KRM55_003048"
     CDS             10455..11801
                     /gene="rpoN"
                     /locus_tag="KRM55_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBH1595261.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT         4928 a         1421 c         2487 g         3470 t
ORIGIN      
        1 gttgaaaaag ctgattgcta tacaggaaat actatagaaa gtgaaagatt cttcccaggt
       61 tggttatatg atgaagaaga tgaatttgtt caagcagcgt ataagggatt aaaagaagct
      121 ggaatagatt cagaaataac tcaatactca ttctgtacga atggaagtca ctacgcaggt
      181 gaggctggaa taagaactat aggatttggt ccttctaagg aaaatcttgc tcatacaata
      241 gatgagtata tagaattaga ccaattattc aaaggtgcag aaggatatta tggtatatta
      301 aaatcagttt ataaaaaata attaggagat ggttttgtga gaactttaat aaaacatggg
      361 cttatagtag atggaaataa aacaccagca tatgaaggag atattttaat agaaaacgag
      421 aaaatattaa aaatatcaca agatttaaac gaagaagctg acaaagttat agatgcaaaa
      481 ggtagagtta tatgtccagg tttcatagat actcatagcc attcagacct agttatttta
      541 gttaatccat ataatgaggt aaagattaga cagggaatta caacagaagt gttgggccaa
      601 gatggtatat ctatggcccc tctacctcaa gagcatatat cttcttggag aaaaaattta
      661 gcaggtttag atggtgaaag tgatgaaatt gattggaaat atgaaacaac agagaattat
      721 ttaaaaatga tggattacaa tggggtaggt ttaaatgaaa cttatttagt acctcatgga
      781 aacgttagaa tggaagctat gggacttgaa gatagacctg ctactaaaga agaaattcaa
      841 aaaatgtgtg aaatcacaga gagagaatta aaagcaggag ctataggatt gtctactgga
      901 cttatatata taccttgtgc atactcattg actgaagaaa ttatagagat gtgtaaggta
      961 gtagcaaaat atgatggagt atttgtagtt caccaaagaa gtgaagcaga tacaatttta
     1021 acttcaatgg aagaaatcat agaaattgga aaacaatcag gagtaaaagt tcatttttca
     1081 cattttaagg tttgtggtaa agcaaactgg aagtatatac cacaagttat agagctttta
     1141 gaaaaagcag aaaaggaagg aataagagta tcttttgacc aatatccata tgcagcagga
     1201 agtacaatgc ttggagtagt tttacctcct tgggcacatt ctggaggaac tgataagtta
     1261 atagaaagat taagtgatga aaacgaaaga gcaaaaatga aaaaagatat agcaaatgga
     1321 atagaaggct gggataattt tatagaattt gctggaatag accaaatatt tgtaacaagc
     1381 gtaaaaacag aaaagaataa agatacaatt ggtaagaact tattagaaat tggaaaaatg
     1441 agaggaaaag acccattaga tgcaacgttt gatttattaa aagaagaaga aaatgcagtt
     1501 gggatggtag atttctatgg attagaagaa catataatag gattcatgaa aagagacgag
     1561 caaaatgtgt gtacagatgg tcttttagca ggtaaaccac atccaagagc ttatggttct
     1621 ttccctaaaa tactaggaag atatgttaga gaattgaatg tactaacaat cgaagaagct
     1681 gtttataaaa tgactaaaaa ggcagctaca agctttagta taaaagatag aggcgaatta
     1741 aaagaaggat attttgcaga tatagttata tttgacaagg atacagttag tggttgtgat
     1801 gattttatca actctatgca gtaccctaca ggtatagatt acgtaattat aaatggaaat
     1861 tgtgttgttg aagaaggaaa atacaataaa attaaagcag gaaaagtact taaaaattaa
     1921 atcttagctt taaggaggaa taaatttatg attttagtgg ggaatgggag gctaataagc
     1981 caagattctt taaatcccta tatggaagat ggatgtgtag taataaatga taatctaatt
     2041 gaagatatag gtactacaga agaaatgaaa gctaaatatc cagtacatga atttatagat
     2101 gcaggcaaga aaataatcat gccgggtcta ataaattcac atatgcatat atacagctca
     2161 tttgctagag gaatggcagt tccaggaaaa ccttctgaga actttttaga gatactaaac
     2221 aatttatggt ggagacttga caaacagctt acactggaag atacaaaata cagtgcatat
     2281 gcaacgtata tagaatgtat aaaaaatggt gtaacaacag tttatgacca tcatgcaagt
     2341 ccaaatgcaa ttgaaggcag tttgtttaca atatcagatg ttgcaaagga tttgggaatt
     2401 agaacgtgtc tttgttatga agtgtctgat agagatggtg gaaatacaat ccaacaaggt
     2461 atcaatgaaa acgtaaactt tataaaatac actcaaaaag atgatacaga catgataaaa
     2521 ggaatgtttg ggcttcatgc tgcatttaca ctatctgatg atacattaaa taaatgtgct
     2581 tcagagatgg ctggtcttga tacaggttac catgtacatg ttgctgaagg actagcagac
     2641 ttacaatata atgtagataa atatggaaaa agggttttag aaagattcaa tgattttgga
     2701 gtactaaaag aaaaaacaat agcagttcat tgtatatata taagtgcaga agaaatcagt
     2761 cttttaaata aaacaaatac atttgtagtt cataatccag aatctaatat gggaaatgca
     2821 gttggatgtt ctcctgcaat agagttatta aaaaggggag ttacagtagg attaggaact
     2881 gatggatata ctagcgatat gtttgaatca ttaaaagttg ccaatataat tcacaaacat
     2941 cacttaaaag acccaagagt tggatttgaa gaatcacaaa caatgttatt tgataacaat
     3001 agaaaaatag ctaaagctta ttataaaaat gacctaggag tacttaaaaa aggtgcttat
     3061 gcagatgtta tagtagttga ttatatacca catactccat tgacagaaaa tacaataggg
     3121 ggacacacta tttttggaat gagtggaaga agcgtagata caactattat aaatggaaag
     3181 gtacttatga aagatagaaa gttaataaac atagatgaag aaagtattct agcaaaaagt
     3241 agagaattaa gtcaaaatct atggaataga atttaaataa ttgatattaa tatacaagta
     3301 agaaacaaga atttagatgt taaaaacaga gcttaaacaa aaataggaat ttaaatgaag
     3361 tatataaata aaaaatatac ggaatagaat attaaattaa atatagaagg gagacccaaa
     3421 atgtctcgag ataaaagccc taaaatagct ccagtagatg aaaggttacc tgtatccaaa
     3481 tcttgggtat tttcactaca gcacgtttta gcaatgtgtg caggagcagt agcagttcct
     3541 atgatgatag gaagtgctgc acgactagat catgctagta ttgttttttt aataaatgct
     3601 tgcttgttta tggcaggtat aggaacactc atacaaagtg ttggtatagg aaatattgta
     3661 ggtgctaaaa taccagtaat agaaggaact agttttgccg ctgtggcagg tatgacagca
     3721 atagcctcat catatagtga ttcacaagtt gcaatacaga cagtatttgg ctctgtaata
     3781 gtagctggat tgttttgtat attacttgct ccagtatttg aaaaattaat aagatttttc
     3841 cctagtgtag ttactggaac agttgttatg gtaataggta tttcactatt tccagttggg
     3901 ataaaatgga taactgacaa caaattggaa gcggttgaac caaactcatt agcattagct
     3961 ttagcagtat tggcaataac tttactttca tttaaattct taaaaggaat ttggaatagc
     4021 acagctatat tggtaggtat agtacttggt acactacttt ccatggcagt tggaatggca
     4081 gattttagtg cagtaaatgg agttggttgg cttaacttaa atgtaccttt aaaatttgga
     4141 atgcctagat ttgaaccatc tgcaatacta tcattgtgtt tgattatgtt ggtacttatg
     4201 acggaatcag ttggtaatat gatagctatt catgaaatgg tagacaagga agtaacaggt
     4261 aaaaatatta aaagaggtct atttggagat ggaatatcta cagcattatc tggaatattc
     4321 aattcatttc caataactcc atttggtcaa aatacaggaa tagtaggtct tacaggtata
     4381 aaatcaagat ttatagcagt ttacgcaggg gttatattgc tagtacttgg attcttacca
     4441 aaatttgcag caataatagg agcaatacct aagcctgttc ttggaggcgt aggatttgca
     4501 atgtttggaa tggtaatggt tggaggagta aaaactttaa gcaaagtgaa atttgatgga
     4561 actaaaaatg gggttatagt agcagttagt gttggtttgt ctatgatacc actaacaaat
     4621 cctgatttct atcataattt cccaacttgg gtacaaacaa tattccatag tggaataaca
     4681 acaggtagtt tatcagcagt gcttttaaac atattcttca atgaactagg ttctaaaaaa
     4741 gaaaaaaata ataaagttga agaagcaaaa taaaaataaa acaagtaaaa atctatattg
     4801 acttaaagtc attaagtatt aataaaaata attcagagat attaataatt caacaaaact
     4861 atcttatatt ttaaataata taaaaaagta aataaataac aaatacaaat aaaagaatac
     4921 aatctaaata ttaaaaatat ttaatttaag ggagagataa taatatggct aatttaaaag
     4981 ttaatttata tggaatggaa tttttaaacc caattatgac agcggcagga cctggagcaa
     5041 aagatggtgc tctctgtcaa gaggcagcaa aaggtggagc aggagctata tgtacaaaaa
     5101 ctatatctgt attaccagct gatgtaccaa gaccatgtat ggcaaaaact aatagtggtt
     5161 ttttaaacac agaattatgg tcagagcttc caaaagagca atggatagag gaagaataca
     5221 aaaaggtaaa agaaacaggg cttccagtaa tagtaagtat gggatattca gcagagcaaa
     5281 tagctgaggt tgctccttta gtaaagcctt atgcagatgc agttgaatta tctactcatt
     5341 atgtaggtac agacgttgca ccaatagtaa atgctttaaa agctgcaaaa gctgttttag
     5401 atgtaccagt atttatgaaa atgagtcctc atactgacat tcaaactatt gcaaaagctg
     5461 ttgaagaagc aggtgcagat ggacttgtaa tgataaactc atttggacca tgtatggcaa
     5521 tagatgtaaa tacaggatac cctataatgg gaagtaaagc tggatacgga tggttatcag
     5581 gtgcaccaat aagacctcta gcaataagat gtatatatga agcttctcaa gttgtaaata
     5641 taccaataat cggtgttggt ggaatcactt gtggaaaaga cgtggctgaa atgatgatgg
     5701 ctggagcaag tgctgttcaa gtatgtacag aagcaatcct taaagggcct tctatctatg
     5761 gaaaaattgc taaagaatta aatgaatttt tagatgagaa tggatatgct gatgttaatg
     5821 aaataaaagg attaactcat aagaaaatgg cagctagagg gtttagaact cattcagtag
     5881 ctccagtagt ggatgataac aagtgtatca aatgtaagca atgtgtaaca agctgtgtat
     5941 acgaagcttt agaagttaca gataagttga acatagatgc agacaagtgt tttggatgtg
     6001 gattatgtgt aactagatgt ccaaaaggag ctttaagcat ctgctacaat caagtagaag
     6061 ctatgaatga gtaataatta tatagaattt tggtaattaa cttagagtaa taggtattag
     6121 gataataaaa tatatcagat aaacaaacac acattatgca ttaataatac agtctaaagt
     6181 taataatttt attatattga tttaactaaa tattagttta gctaaatatt aatttaatta
     6241 ggtattggtt taatcttaat atagatttac tgcgtataag tgaactaact agattacttt
     6301 aagttaattt tttcatataa aataaattga tacattacaa gtaaggtgga gtctatatgg
     6361 gaattgtttt aaaaggtggg aaagtaataa caagtgaaaa aacttactgt gcagatgtaa
     6421 gaatagaaga tgaaaaaata gtcgatatag gtcttgatat atcaaaagaa aatgatgaaa
     6481 tagttgatgt tagtgattct tatgttatac caggaggtat agatacacac acacactttg
     6541 acttagatac aggcgttact aagacagcag ataactttga gacaggaaca aaagctgcta
     6601 tagtaggagg aactactact atattggatt ttgctacaca agctaaagga tgttctttga
     6661 aagacggatt agaagaatgg catgaaaaag ctaaggataa atcctattca gattatggct
     6721 ttcatatggc tataacagat tggaatgact cggtttgtaa tgaaatggag gatatggtga
     6781 aagagggagt atcttcattt aaactgtata tggcgtataa aggaagcctt caagttgatg
     6841 atggtgtaat ctttgaagca ttgagaaaag cagaagagat aggagggatt attggtttcc
     6901 attgtgaaaa tggggacata atatgtgaac ttgtggataa agcaaagtca gaaaataatt
     6961 tatctccaaa atatcatcaa ttaactagac cagctataat ggaggcagaa gctacatcaa
     7021 gacttatgaa gatagctgaa gttgcaaact ctaaagtata tgtagttcac ttaagctgta
     7081 aagaatcctt agaggaggtt ttaaaagcta agcaaagagg tgtggatgta atagttgaaa
     7141 cttgtcctca ataccttcta ttaaatgatg aattatatga tttagatgga tttgaaagtg
     7201 ctaagtatgt aatgtcacca cctttaagaa ataaagaaaa taatgaaata ttatggaatg
     7261 ctattttaga taatcaaata gacactatag gaacagacca ttgttctttt aattataagg
     7321 gacagaagga acttgggata aacgatttca gtaagatacc aaatggttct ccaggtgtag
     7381 aacataggat gagtctttta tacacatatg gagtctgtaa aaataaaata tctatcaaca
     7441 agatggtaga agtaacatca actaatgcag caaagttgtt tggaatgtat cctaataaag
     7501 gaactataga aataggcagt gatgcagata tattagtctt aaatccaaac aaaaaatcca
     7561 aaatagaagc aaaaaaacaa ttacaaaatg tagattatac accttatgaa gggtatgaag
     7621 tggattgtca aatagaacat gtttatttaa gaggaaaaga agtagttaga gatggagaat
     7681 taatttgtaa tactccaagt gggagatata taaataggcg tctaacaaag ggggctagag
     7741 aatggtagaa tttatattaa atggagagaa agttgttgca aaagaaggca aaaaactttt
     7801 agacttcctt agagaagata tgaatataac ttcagttaaa aatggatgtt cagaaggtgc
     7861 ttgtggaaca tgtatggtta taatagatgg taaagctact aaagcatgtg tatttaaaac
     7921 tgataaatta gctgggaaaa acataacaac tatagaggga ttatcagaga gagaaagaga
     7981 tgtttttgca tattcttttg ctagtcaagg agctgtacaa tgtggatttt gtattccagg
     8041 tatggtaatt agttcaaaag cacttataga cgttaataat aatcctactg aagatgatat
     8101 aaagaaagct ttaaaaggca atatatgtag atgtacaggg tatgtaaaaa taattaaagc
     8161 tgtcgattta gcagcaaaga tttttagaga aaatatagat gtgccaaaag taaactgtaa
     8221 gggtctagta ggtgaaaatc ttcctagagt tgatgcagtt ggcaaagcac ttggatattc
     8281 tgaatatgta gatgatatga gaattgaggg tatgatttat ggttcagcag ttagagctaa
     8341 gtatcctaga gctttagtta aaaaaataga tatagaagaa gcaaaagctt atccaggagt
     8401 tgttgcagtt ctaacagcta aagatattcc aggaactata aaggtagggc acttaaagaa
     8461 ggattgggat actttaatac cagaaggtga aataactaga tacttaggag atggaatagt
     8521 tttagtagca gcagaaacta gagaagcgtt agaagaggcc aaaaagctag ttaagataga
     8581 ttatgaggaa ttaacaccat taagtactac aacagatgca cttagagaag atgctccaaa
     8641 gatacatgag acagggaata tacttgttaa ggaacattta gtaagaggaa acgctaaaga
     8701 aaagatagaa aattcaaaat atgttgtaac taaaagatat actacacctg ctacagaaca
     8761 cgcattttta gagcctgaat gtgcagtagc tggtccttat gaagatgatg gagtaataat
     8821 ctattcaaca gaccaagggg tgtttgccac tcaacatgaa tgtgcagata tgttagggtt
     8881 accatatgag aaggtaagag ttataaacaa aatggtagga ggagggtttg gtggaaaaga
     8941 agacatgagt gttcaacacc atgcagcctt acttgcatac catacaaaga gatttgtaaa
     9001 agtacagtta acaagaaaag aaagtattat tgttcatcca aaacgacatg ccacagaaat
     9061 ggaatttacg acagcatgtg atgaaaatgg atacttaacg ggtatgaagg caacgataat
     9121 atctgacaca ggtgcatatg cctctcttgg aggaccagtg ctacaaagac tgtgtactca
     9181 tgcagcagga ccatacaatt atcaagatat tgatataaca ggaacagcag tatatactaa
     9241 taaccctcct ggaggagcat ttagaggatt tggagttaca cagagttgtt ttgcaactga
     9301 atgtaatcta aatttacttg ctgaaatggt tggaatatct ccttgggaga taagatataa
     9361 aaatgcaata agacctgggc aagttttacc aaatggtcaa tttgcagatg aaggaacagc
     9421 aatggcagag acactagaag ctgtaaaaga agagtatgaa aagcatccac gtgcaggtat
     9481 agcttgtgct atgaaaaata gtggggttgg agttggtata cctgatgttg gaagatgtag
     9541 attggtgata aaagatggca aagttcacat aagaacaagt gcttcttgta taggtcaagg
     9601 gcttggtact gttatgactc aagtagtttg tgaaactgct aacctacttc ctgaaaatat
     9661 agtgcatgaa gttccagata ctcatttaac accagactct ggtaatacta cggcttcaag
     9721 acagacagta tttacgggag aagctactaa ggttgcatca aataagttaa aagaagcttt
     9781 agactctggc aaaactttac ttgatttaga gggagaagag ttttatggag aatatgaaag
     9841 tattacagat aaaatgggtt gtgacaaaga aaatccagta agtcatgttg cttatggata
     9901 tgcaacacaa gttgtaattc tggatgaaaa tggaaaacta gaaaaagtag tagcagcaca
     9961 tgatgttgga agagctataa atccaatcag tttagaaggt caaatagaag gtggagtagt
    10021 tatgggtctt ggatatgctc taaccgaaga ttacccagta gtcaactctg ttcctacagc
    10081 taagtttggt acattaggtt tatttaaatc tacagatata ccagaaatac aagctttaat
    10141 agttgaaaag aacaaagatt tattggctta tggggcaaaa ggtgtaggag aaatttgtac
    10201 agttcctact gcaccagcag tacaaaatgc ctattatgta tttgataaag aatttagaac
    10261 tgagctacca ctacaaaata ctccatatag taaaaaaaag taacaaaaaa aagaaatatt
    10321 aaataaaaaa atagatgaaa ttgtaaataa aaaaaaccct tttgcataag gtatatttta
    10381 aatgatagaa tatacatata caggagggtt tttcttttat aaaataagtt taataaaatt
    10441 gagaggtgag cagaatgaat tttaataata gtctagaatt aactcagtct cagaagctaa
    10501 taatgactac acaacttaag caatcattat caatattaaa tatgagtaag ttagagttag
    10561 aagaagagat aaaaagagaa gcagagaata acccattagt tgaagtcgag aaaagtgggg
    10621 agataaattg ggaagagtat ataaaagaca tggataggtc aagacgttta gatagaacag
    10681 agataagcta taatcctgat aatgaagtta atctagaaaa tttagttaaa tattcgtcaa
    10741 atttatatga agatttaaaa tttcagataa gcctgtataa acttacagac aaagaattgg
    10801 aagtctgtga gtatataatt gatagtttag atgaggatgg atatttaaga actgaggaaa
    10861 aagtaattgt tgatacctta aagatagatg aagaactttt tgaaaaatgt ttaattagtg
    10921 ttcagcagtt ggaacctagt ggagtagggg caagaagtct ttcagaatgt ctgatgatac
    10981 aaatggctag tttaggaata tataatgaaa ttttagagga aatcgttaca aaagacttaa
    11041 atttaattgc aaataataaa tataaagaga taagtaaaaa gtacaatatg tcattacaaa
    11101 aatgtgttga actaataaac ataattaaga cattagaccc caaaccagga agaacttgtt
    11161 cagtagagaa aagtgtatac attcaacctg atgtaacagt agaaaaaatt gatgatgaat
    11221 ttattgtata tttaaatgag aaagattctt atcaaataag aatcaatagt tattataaag
    11281 acatattaaa aaattcacag tctgatgaaa gtgcaaaaga atttataaaa gaaagactaa
    11341 attcagcaac aggacttatg aaaaatatag agagtaggaa aactacagta cttaagattg
    11401 cagaagagat agtaaaagct caagatgaat ttttgagaaa agggacaaaa tatataaaac
    11461 ctttgaaaat gaaagacata gcagaaaaat tagaatttca tgaatctact ataagtagag
    11521 gtgtaaatgg taaatatatg ctaacacctt ttggcgtata tgaatttagg tactttttca
    11581 gtagcgccat tgagactgag aataatgaaa tggcatctag tacaagcata aaaaaaatta
    11641 taaaggaaac aataaaagac gaaaataaaa agaaaccttt aagtgatgac catatatcta
    11701 agttattaaa agaaaaagga atcaatgttg caagaaggac agttgccaaa tatcgtgaag
    11761 aattaggaat cccatcttca agtaagagaa aagaatacta ataagtaaaa gacaaatatc
    11821 agtatggtaa ggggaaaagg ctaattaaga gatgaatgta gattgggcta aaaattttat
    11881 aaagtaaaat aatagaatat ggaaaagtat taaaatgcta taaggtatta aaaaactggg
    11941 gaacattaaa acattaagat agcaaagaac ataaaaaact aaagaagatt aaaacattaa
    12001 agaacattag agctttgagg aatattagaa ctttaaagaa tattaaaatt tataaaatat
    12061 aaaaatacta aaaagaattg aaaaactggg gaacattaaa atattgaaaa atgctaaaaa
    12121 actagaaaac ataattaaat aagtgcttat aaagaatgat taaattaaat aagtgtttgt
    12181 aaagaataat tagatattag aaaaagaaga atacctagat aaataaacta ttattaaatt
    12241 taataatcac aaaaggaaaa cacgtagggt ataaataaaa atcttaacta gataaaagta
    12301 aactta
//
LOCUS       DAEPXW010000106        12204 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.109, whole genome shotgun sequence.
ACCESSION   DAEPXW010000106 DAEPXW010000000
VERSION     DAEPXW010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12204
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.109"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            77..1081
                     /locus_tag="KRM55_003049"
     CDS             77..1081
                     /locus_tag="KRM55_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1595262.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGIKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1207..2319
                     /locus_tag="KRM55_003050"
     CDS             1207..2319
                     /locus_tag="KRM55_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1595263.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLLTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELIVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2808..3569
                     /locus_tag="KRM55_003051"
     CDS             2808..3569
                     /locus_tag="KRM55_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595264.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3572..4390
                     /locus_tag="KRM55_003052"
     CDS             3572..4390
                     /locus_tag="KRM55_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBH1595265.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4570..5172
                     /locus_tag="KRM55_003053"
     CDS             4570..5172
                     /locus_tag="KRM55_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBH1595266.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     misc_binding    5780..6018
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6082..8001
                     /gene="thrS"
                     /locus_tag="KRM55_003054"
     CDS             6082..8001
                     /gene="thrS"
                     /locus_tag="KRM55_003054"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBH1595267.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            8769..9849
                     /locus_tag="KRM55_003055"
                     /pseudo
     CDS             8769..9849
                     /locus_tag="KRM55_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(10069..11106)
                     /locus_tag="KRM55_003056"
     CDS             complement(10069..11106)
                     /locus_tag="KRM55_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBH1595268.1"
                     /translation="MNKKLIKAKIFIWSILAISLSIVFISFLIGTIISHSFNFPFNTL
                     NPKYNYDNYIVAKNESFSDKINDINVDWISGEVRIKRSDSNKIKLIQKIPSNFSKKKL
                     AKIMVDGNSLSIYDNSTKKFFIGINLPKPTILELYLPNKLYDKITLYTTSADIYSTYI
                     RSNIVEANTISGAIGLSGNINKINLDTTSGHIDITKLNSKNATLKSTSGEIQLSGKID
                     VLNLETTNGNINLKDIYNKNLTCSSVSGKMNLSGVFSDIKAESTSSNIKINSSKMLSS
                     LYCETTSANVDLSIPDNPGFTLNFDKVSGVLDSDFELNRHSDLYTYKNGITDLYLSTT
                     NGNLTIIKNNH"
     gene            complement(11099..11785)
                     /locus_tag="KRM55_003057"
     CDS             complement(11099..11785)
                     /locus_tag="KRM55_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595269.1"
                     /translation="MLDKIRTYIDSSFTGVNETKKVKELKDELFENLKEKYNDQIQDG
                     KTEQEAYNSVISGIGDLSELIESVKEPYSLPSELIEEKKKRALRASIAVALFIISPFL
                     FVVSVVSFGIEPTIAILLMLILIALGVGLLVYNQMTRTNYALYNDNLSNKFKEFEDFE
                     ENYNHINPVYKSFMNAYWIIIVSIYLITSILFNIWSFSWILFIIGAAGVNIVKGIIQL
                     KGYKEEDKYE"
     gene            complement(11797..12117)
                     /locus_tag="KRM55_003058"
     CDS             complement(11797..12117)
                     /locus_tag="KRM55_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595270.1"
                     /translation="MIIASDMIRGHTETIILKHLLEKDSYGYEINKSILEKTKGLYEL
                     KEATLYTAFRRLEQSGAITSYWGDEVTGARRKYYSITNIGKEKYIKSHEEWNNTKALI
                     DILI"
BASE COUNT         4788 a         1276 c         2077 g         4063 t
ORIGIN      
        1 taggatgtaa aagtaagtag gatgtaaaaa taaataggat ataaaaatat cgtaaatgta
       61 tgaggagtga aatttaatgc gtttcaaaag aatattgata ttgatgttaa ctgtagcaat
      121 gatagctgga atgttggttg ggtgtgctaa taacccaagc aataatccta gctctagcaa
      181 agataataaa agtgatataa gcgataaaag taattcaaaa aaatctgtat caatgatact
      241 agatattgaa ggaacaaata atgaagctat gaataattca gctttattag cattaaacaa
      301 tgctcaaaag aaacttaata tagatacaaa caaagtggaa tcagatgatt cctcaacttt
      361 ttctaatagt atagatattt tatgtaatga caattacgat ttaattatag ctgtaggagc
      421 tagatttgca aaaccattgg agatggtagc caagaaatat ccaaagcaac aatttgcaat
      481 tatagactat gagtatgaca agcaaccttc taatataact tcaatttctt atgaagataa
      541 taaatctgga tacctagctg gattaattgc tggaaaaatg actgaaagcg ataaggttgg
      601 ttttatagga ggaataaaga gctctagtag ggataaattt gaatcaggtt ttagagaggg
      661 tgttaaattt tctaatagca gtataaagga tatttcagtt gagtatgcag atgtttttaa
      721 agatagcaaa tcagtagaat ctatagctaa aaaaatgatg gataatggag tggatattat
      781 tttttctact actgaagatg attcaaaagc tgtaatagat gcagtaaggg caaaaaataa
      841 aaaagttata gcaacgaata aagaccaaca tgagttagct ccagaaaatg ttataagttc
      901 tattgtaaaa gattttgaga atcctactta taatctgata caaagttttg taaaaggaaa
      961 ttataaaggc ggaaaagtta tagaaaacac agttaagtct ggaagtactg ggcttgccca
     1021 aaatagttct caaaatattc ctccagatgt gttagaatat gttaataaga acaataaata
     1081 atctactata atatccaaga atacttatga ctttagttat gaggtgaatt ggatgttata
     1141 atagacatat atagaaagac atatgcagag gtaggttaga cctatctaaa tcagggagtg
     1201 aattttgtga aaataaaaag gatattgatg gcttgctttg tagtagtttt tacaattttt
     1261 atattagcta tatgtaattt tgattttgga tttgataaag taaataagaa taattctaat
     1321 atagatagtg ctaaatcgaa acagagtgag tctaaaagtt tgctaacttc agcagaaaag
     1381 gataaatcaa atagtaaaag taagaataaa gaagatgaca cagaagatga ttcatatgta
     1441 agaaaaacta ttggagtatt gttagatacc gaaaacttaa ataacgaatc atataataac
     1501 aatgtactat cagccttaaa aagggctgac gaagattttg atgttaggat aaaacttgaa
     1561 aaaccaaaga cttctaaaag ttttaaagag agtatagaaa aactgcataa gtatgaacca
     1621 gatttgataa tagcagttgg agccagattt gcagagccaa ttaaagaagc tgctactaaa
     1681 tatcccaaac agcaatttgc aatagttgac tatacttata aagttcagcc agctaatgta
     1741 atttctgtat catttcaaga taatgttact ggatatttag caggacttat tgcaggtaaa
     1801 atgactgata ctgggaaagt cggttttata ggaggagttg agggttctag tagagataag
     1861 tatgaatctg gatttagaaa ggggcttaaa acttcaaata aagatgctga gttaatagtt
     1921 aagtattcaa atatatttga aaaccctgaa tcagctagaa ctattgcaaa ggaaatgaga
     1981 gattctgata gagatgttgt attttcagct acagaagatg atagtaaaag agctattcag
     2041 gtagcaagag aaaatggtgg taaagttata gctattaata aagaccaata cgatatggct
     2101 ccagataatg taataagttc aattataaaa gatgtagaac aacctgtata tgaactgata
     2161 aagaacgttg caaaagatgg ttttaaggga agtaaagtaa tggaatttaa aataaaagat
     2221 ggggaacttg gcttgacttc aaagagcagt agaaatatac caccagatgt tttggaatac
     2281 ataaaaaaag agtataacaa agtgaaagat acatattaat tattgagtag aagattataa
     2341 aaatatactg cttaagttta gattggtgat aaaaggatat atttattaaa tttgtgctaa
     2401 ctgtacaaaa tatattgatt aagtttagat tagtgataaa aagatatatt tattaaattt
     2461 gtgttaacag tatggaatat actgcttaag tttagattgg tgataaaagg atatatttat
     2521 taaatttagt ctaactgtac aaaatatatt gattgagttt aggttagcaa taaaaagata
     2581 tatttattaa atttagtcta actgtacgga atatactgct taagtttaga ttagtgataa
     2641 aaagatatat ttattaaatt tgaaccaact gtacaaagct atactaatta aacttagatt
     2701 aactatataa aattataaca ataagtgtgt gggcagaaaa attctgctac acactttatt
     2761 tatattcaca taaaaaattt atcaaaaaaa agaaaaagga gtaaaaaatg gaatttacaa
     2821 gagaaccatt tatactagat gacgatttgt gtctagcttt ggtggacaaa agaattagtt
     2881 atctaatgga aaatgaatta aaattaagaa atatagagat aataaaaaca atagaatgta
     2941 aagaattata tgaaagcata aaatatcacc cggatatatg tatttgtaat ttaggaaaag
     3001 gagatataat tgttgcgccg aatgtatata atcaatacaa agagttatta agtagatata
     3061 aatttaatat aattaaggga gaagctaatt tattaaatag atacccttat gatatacctt
     3121 acaatattgc gatagttggt gactatgcta tacacaattt taagtatact gacaaagcaa
     3181 tattagatta tattgaaaat aataaactta aaaagataaa tatagagcag ggctattcta
     3241 aatgctcaat ctgtatagta gatagaacgt ctataataac atcagataaa ggtatttgga
     3301 aaagtatgaa gaatacagaa atagagtgtt tattgataga aaaaggtcac ataaatttat
     3361 ttgagatgaa ttatggattt ataggtggat gtacagggtt gatttctaag gataaactag
     3421 ctttttgtgg agatgttaaa aaacatcctg actatgaacg tataaaaagt tttgtagaaa
     3481 gtaaaaacaa ggagatagtt acacttagct gtgaaaattt actagatata ggttctatag
     3541 ttcctctcat gacaagaaag gagcgataac tttggttgag aaggataata tttcttccat
     3601 gaaatttttg aggaataata atgtaaacga tagattaata tatacgaatg acattgtaga
     3661 agtagtgata gattctgcaa agcaagaagt gttaaataaa aaaatactta atggtactaa
     3721 agctgaacaa agagctttaa atattgatga gatatcaacg gaaataacta gtatgataat
     3781 aagtataatg aaagagaaac ttttgaaaga atacattcta aaatgctatg ggcgtacata
     3841 tcctgaagat aaaaataata tatacatata ttcactgaac atatttgcta aaaaagagat
     3901 ttttatgaga gaaacagtat ttactagggt gagaaattat atagaagaaa atgattttat
     3961 aaatgtagaa ggttttatta gatttagaat gagagaattt atgaaatata tttctgctat
     4021 aggtgatatt gcagttgagg agtatttaat aaagaaagac caagatgaat ttataagagt
     4081 tttaaaatac tttatagata ctcaagaaga aaagattgat ttgcttaaag ttcatataat
     4141 ggaagataat acatttgttt tatacgataa aaatggaaat aagatagaca gtatagatga
     4201 tgaagaaatt ataaatatgg taataagaga aaatttaaat tatgaggact ttttaataag
     4261 taccttatta actctatgtc ccaaaaaaat agaaatattg gatttgttaa ataataattg
     4321 ctcaaaggaa attatagata ctgtagaagc aatttttgaa aataaagtta gtataattat
     4381 ggaaaactag aatctaagca tataaaagct agccatataa aattaaaaaa attcttttta
     4441 aatcgacaca aaagacttat aattgtatat aaagctatag tataactaga gttattaagt
     4501 ataaagaata tctacttgat taatgcaata tagctggcaa atatacaatt gataaggagt
     4561 aattttataa tggataattt aattaggata ctgatattag ctgttattgg tggatttata
     4621 ggttatgtta cgaatgtagt tgctataaga ctgatattta gaccaataga gcctattaaa
     4681 atacctattt taaatataga aatagtaggt cttataccaa agagaagagc agaaatagca
     4741 gcaaatgtag gagaaataat tcaagaagaa tttctttcta tggacgaaat acttgcaaat
     4801 atcattactg acgaagataa ggaagaagtt gtaagataca taaaagcaag ggtaaaaatt
     4861 ataatacatg agaaagtttc atttatcccg agtggtataa aaaacatgat acaagattat
     4921 ctaggagaga taattgagtc tgaagttaag caaagtatag atgaattgag taaaaatata
     4981 ataaataaag caaatgaacg tatagatata caaaaaatgg tcgaagataa gattaatgaa
     5041 ctagatttat atgaattgga agagataata ataagaatag ctaagaaaga attaaaacat
     5101 atagagtttt tggggcttgt cttagggttt ttaataggta tagctcaagg gttaattact
     5161 atgtttattt aaatatatga gaagtagcat ttatttaagt attaattgta tttacctatt
     5221 tgagtgaatt acttattaat aacatttaga tattaattgt atttacctat ttgagtaaat
     5281 tacttattaa tagcatttag atattaattg tatttaccta tttgagtgaa ttacttatta
     5341 atagcattta gatattaatt gtatttacct atttgagtga attacttatt aatagcattt
     5401 agatattaat tgtatttatt tgattgtgtt acttattaat agtatttaag tatttactgt
     5461 actacttatt aactatatta agtattgatt gtatttaagt atacaaaacc taaaaagagt
     5521 acaaaaatta gaagttagtt ttaataaaaa ttagttttag tatttatcta gtcatatcta
     5581 tcatgcatgt ggatacgttt taaaaatttt aaatttatga aaatattata atatcactat
     5641 aaatcaagag attaatttaa tataaaaata taagaatatt ggtttacagc tgattgagat
     5701 gaaaaataat gggtaattaa tatattacat taatgttgat tgatgtataa ctatctgtta
     5761 taatgaaaat atattaaaaa tcatagtgtt gaagaggaag agtagagtag aaaccattct
     5821 cagagaattt gggtctatgg ctgagagccc atgtaatagg tctatttgaa aactaccttg
     5881 gagctgagct tattagcagt atttgtattt gtactatacg tgaaagtgct cgggtgacga
     5941 ccttatagtc atcaagaggg ttgtatatac ttgtatacgc caacttgggt ggaaccgcga
     6001 attaatatcg tcccaaacat atttggggcg attttttatt acaaaaaatc taaaaattat
     6061 ttcaataagg aggaaaaaac aatgattaaa gttgctttaa aagatggctc aataaaagaa
     6121 tttgaaaatg ctatttctgt tatggatgta gctaaatcca ttagtgaagg attagctaga
     6181 aatgtggtag cagcatctgt gaacggagag gttgtaggtc tggaccacat tatagatact
     6241 gattgtgact tgaatttatt taagtttgaa gataaagaag gtaaggaagt ttttagacat
     6301 acatcagcac atatattagc tcaagctata aaaagacttt acccagaagc aaagcttgct
     6361 ataggaccaa gtatagaaaa tggattctac tatgatatag atttagacca tagattagtt
     6421 ccagaggacc tagagaaaat agaagctgaa atgaaaaaaa tagctaaaga agatttaaaa
     6481 atagaaagat ttgaacttcc tagaaatgaa gctttagagc ttatgaaaga acaaggagaa
     6541 gactataagg tagaacttat atctgattta cctgaaagtg aaataatatc tttctacaag
     6601 caaggtgatt ttactgattt atgtagagga ccacatttac catctactaa aaaggtaaaa
     6661 gctgttaaat tacaaagtgt agcaggtgca tattggcgtg gtgacgaaaa taataagatg
     6721 cttcaaagaa tatatggaac ttcttttgag aaaaacaaag acttagaaga gtacttacat
     6781 ttactagaag aagctaaaaa gagagaccac agaaaattag gtaaagaatt aggattattt
     6841 atgatacctg aagaaggtcc aggattccct atgtttttac caaaaggtat ggaacttaaa
     6901 aatgaattat taaaattctg gagagaaata cacagaaaag ctggatatat tgagatagaa
     6961 tctccaatca tattaaatag aaaattatgg gagacttcag gacactggta tcattacaaa
     7021 gaaaatatgt atacagttaa aatagatgat gaggattatg ctataaaacc tatgaactgt
     7081 cctggtggat taatttacta taactctcaa ctacattcat atagagattt cccaatgaga
     7141 gttgcagagc ttggtagagt tcatagacat gagttatctg gtgcattaca aggattaatg
     7201 agagttagag catttactca agacgattca catatattca tgttaccaga gcaaattaag
     7261 gacgaaataa aaggagtagc taacttaata gatggtatat acaaaacttt tggatttgaa
     7321 tataatttag aattatctac aagaccagag aactctatgg gaagcgacga agagtgggaa
     7381 gcagcagaaa atggattaag agaagcttta gaagagttag gtctaccata tactattaat
     7441 gagggtgatg gagcattcta tggtcctaag atagacttcc atctaaaaga ttgtttagga
     7501 agaacttggc aatgtggtac tatccaatta gatatgcaac ttccaagaca atttgataat
     7561 acttatattg gtcaagatgg tgaaaagcat agaccagtta tgattcatag ggttgctttt
     7621 ggtagtatag aaagatttat aggtatatta atagagcatt atgctggtaa attcccagtt
     7681 tggttatctc caactcaagt taagatactt cctatatctg ataaatttat ggattatgca
     7741 aatgaagtta agaaagagtt atttgataag ggtataagag ttgaattaga tgatagagct
     7801 gaaaaaattg gatttaagat aagagaagct cagcttgaaa aagtgccata catgttaata
     7861 gtaggtgaaa aagaagtagc tgataataat gtttctgtta gatcaagaga taaaggtgaa
     7921 ataggtagta ttaaattaga tgaatttata gctagtattt caaaagaaat tgaatcaaga
     7981 gaaagtatta ttcaagacta atatataata tattagtagc taagatattg ttatataaga
     8041 taagtttaat caatatgttg atatgttgat gcatagtgat taaatttatg aaaagatgag
     8101 tataattaga ggtacagtta atcatatttt tatgattaat gtacctctag ttttttgtat
     8161 ggtagattta ttaataaata tatcatagaa gtgttttgaa catggaaata tttatgtgca
     8221 ttctttaaat aaaagtttat tttttgagtg ataattaagt gcttgttggt aaggttatgg
     8281 ctgtaaaaat cataacttta ttttcatatt tgttccattt tcataaaaat tattatccct
     8341 ttaagaaaat ttcttaatcc tcttgaaata tttccttttt agtctaaagt taaatttctt
     8401 tcttcaaaat gaatatttaa atgaactaaa atttaagtac attttctaat cttatgagtc
     8461 tatttttcat agataattgc cctataatag aagaatctat gttggagcta tttggtgaca
     8521 ataacagcat tgtcattgat taattaatgc tttataaatg attaattagt tttttatgtt
     8581 atttttggac ttaccctcta tacatagatt aatttattta actttagata gagagagaat
     8641 gtcaagtaca tacacagaca ttagagttta agaaagtgtt tatggagcaa gaacttttaa
     8701 aagaggtagt gacttagttt aatttcaaga aatgataaat acaaaagagg aaaaagagag
     8761 gtgttgaaat gatagaaaaa gtagaagaaa aatctaagat tattaaaaca tcaaaagaat
     8821 ataagcgaac tataattgaa gaaaaagata aagaatggac caaaaaatta aatgatatac
     8881 ttagtagaag tagtttttct aatgatgaat tagataaaat caaggcgtta attccaaaag
     8941 agattttgac taatgaaaat gttggagaag ttgtgactga agatggatat gctaagcctg
     9001 agtatgatga ggtatttaaa tcattgttca ctttaaataa tgaatatgat ttacttgtaa
     9061 attttataaa tgatatccta aaagatgctc catatgctaa caggaatatc aaaccgttca
     9121 ctcaaataaa gagaataatt agagttgaaa ctgacccaac aattaattac attggagaga
     9181 aaagacctag acttgatatt ttggctgaag atgaagagaa taatcatata aatattgaga
     9241 tgcaaagagc ttttgagaac gattatttgg aaagagctga atattatctt agtcgtgtac
     9301 atggtagaaa gttagaagaa ggtaaagagt ataaagaaat tggaaaaact attggaatac
     9361 atatactaaa tcatgtaaaa tataatcaca tagaagatta tgtaaattgc ctgagattaa
     9421 caatggacgg gcatccagat atttattcta gtaaaactgc attatatttt atagagcttc
     9481 caaaaattca taaatctgac tatatagtaa atagaattat gctatgggga aaacttatta
     9541 gtaatccttc tagcttagat gtaagagtta tagctaagta ttaaaaaagc acttgataga
     9601 ttaaaagaat taggtagcaa tgaagaatat ttattaaatc tgaaaagagg tgcttatatc
     9661 atgaataaaa gtagaaattt taaagaagag attgaaagag agacagcaat tagagttgca
     9721 aaagaaaaag attataaaat aattataatg ttgaaaaaaa atggttttaa attagatgac
     9781 atattaaata aatttaatga ttttgactta agtgaagatg agataaaaga agtatatgaa
     9841 aataattgat gataaataaa aagtgaactt atataagttt gctgaatcgg agtctagaaa
     9901 tatttatgtg tattttttaa tgaataaaaa tttattttaa aaacaataat ttagaggtac
     9961 agttaattat atttttatga tactgtactt ctagtttttt ctattgtaga tttattattt
    10021 actaataaat ctacaataga agtgcttttg ttgtaagaat cattttatct aatgattgtt
    10081 ttttataata gttaaatttc catttgtagt gcttaaatat aaatctgtaa taccattttt
    10141 ataagtgtat aaatcactat gacgattcaa ctcaaagtca ctgtccaaaa caccagaaac
    10201 cttatcaaaa tttaaagtga aacctggatt atcaggaata gacaaatcga cattggcaga
    10261 agtagtttca cagtacagag aagacaacat tttgctagaa ttgattttta tattactgct
    10321 agttgactca gctttaatgt cagaaaaaac tccagataag ttcatttttc cagaaactga
    10381 actacaagta agatttttat tgtatatatc ttttaaattt atattgccat tagttgtttc
    10441 taagtttaaa acatcaattt tcccagaaag ctgtatttca ccagatgttg atttgagtgt
    10501 agcattttta ctatttagtt ttgttatatc aatgtgacca ctagttgtgt ctaaatttat
    10561 tttattaata ttaccagaga gacctattgc acctgaaatt gtgttagctt ccactatatt
    10621 acttcttatg taagtgctat atatatctgc tgaagtagta tataaggtta ttttatcata
    10681 aagcttattg ggcaaatata gttcaagtat tgttggtttt ggaagattaa ttccaatgaa
    10741 gaatttttta gttgaattat catatataga aagagaattt ccgtcaacca ttatttttgc
    10801 tagttttttc tttgagaaat tactagggat tttttgaatt aatttgattt tattagaatc
    10861 acttctctta attctaactt cacctgaaat ccaatcaaca ttaatgtcat ttattttatc
    10921 tgaaaaactt tcatttttag ctactatata gttatcataa ttgtatttag gattaagagt
    10981 attaaaaggg aaattaaaag aatgtgaaat tatagttcct ataaggaatg agataaatac
    11041 aatagaaagt gatattgcca ggatactcca gatgaaaatc tttgccttta taagcttttt
    11101 attcatattt atcctcctcc ttgtagcctt ttagttgtat aattcctttg acaatgttga
    11161 caccagcagc acctattata aatagtatcc acgaaaagga ccaaatatta aatagtatgc
    11221 ttgtgattag atatatagaa actattataa tccaatatgc attcataaat gatttataaa
    11281 ctggatttat atgattataa ttttcctcaa aatcctcaaa ttctttgaat ttatttgata
    11341 aattatcatt gtatagagca tagtttgtcc ttgtcatttg attatagact aataaaccta
    11401 ctccaagtgc tattaatatg agcattaaaa gaatagctat agttggttct atgccaaaac
    11461 ttacaactga gactacaaat aggaaagggc ttattataaa aagagcaact gctattgatg
    11521 ctcttaaggc tcttttcttt ttttcttcaa ttaattcaga aggtagagaa tatggttcct
    11581 taacactttc aattaactca gataaatcac caattcctga gattactgag ttatatgctt
    11641 cttgttctgt tttaccatct tgtatttggt cgttatactt ttcttttaga ttttcaaata
    11701 attcatcttt aagttctttg actttttttg tctcattaac tcctgtaaag ctactgtcaa
    11761 tataagtacg tattttgtct aacatatttt cacctcctaa attaatatat ctatcaatgc
    11821 ttttgtatta ttccattctt catggctttt tatatatttc tctttaccta tgtttgttat
    11881 tgaataatac tttcttctag ctccagtaac ttcatcaccc caataagagg ttattgcacc
    11941 agattgttca agtctacgaa atgctgtata caaagtagct tctttcaact catacaatcc
    12001 tttggttttt tcaagtatag atttattaat ctcataacca taactgtctt tttcaagtaa
    12061 atgttttaag ataattgttt ctgtatgacc tcttatcatg tcagatgcga ttatcatgaa
    12121 catcacctcc aattaaatat ataatacttt gatatacttc gcctgtcaag gtatatcatg
    12181 agaaaagata ttttattgta atat
//
LOCUS       DAEPXW010000107        12100 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.110, whole genome shotgun sequence.
ACCESSION   DAEPXW010000107 DAEPXW010000000
VERSION     DAEPXW010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12100
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.110"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            235..417
                     /locus_tag="KRM55_003059"
     CDS             235..417
                     /locus_tag="KRM55_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595271.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            1249..2163
                     /locus_tag="KRM55_003060"
     CDS             1249..2163
                     /locus_tag="KRM55_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBH1595272.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2553..3200
                     /locus_tag="KRM55_003061"
     CDS             2553..3200
                     /locus_tag="KRM55_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH1595273.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3367..3936)
                     /locus_tag="KRM55_003062"
     CDS             complement(3367..3936)
                     /locus_tag="KRM55_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595274.1"
                     /translation="MKKFILCIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(3941..4840)
                     /locus_tag="KRM55_003063"
     CDS             complement(3941..4840)
                     /locus_tag="KRM55_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1595275.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNLCAKKYRGI"
     gene            complement(4851..5000)
                     /locus_tag="KRM55_003064"
     CDS             complement(4851..5000)
                     /locus_tag="KRM55_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595276.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(4993..5577)
                     /locus_tag="KRM55_003065"
     CDS             complement(4993..5577)
                     /locus_tag="KRM55_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBH1595277.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            5966..7291
                     /gene="cdeA"
                     /locus_tag="KRM55_003066"
     CDS             5966..7291
                     /gene="cdeA"
                     /locus_tag="KRM55_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBH1595278.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFISSLLVFIIALVFA
                     PFIVRVFVNPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(7386..8180)
                     /locus_tag="KRM55_003067"
     CDS             complement(7386..8180)
                     /locus_tag="KRM55_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595279.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(8181..9056)
                     /locus_tag="KRM55_003068"
     CDS             complement(8181..9056)
                     /locus_tag="KRM55_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595280.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(9060..9428)
                     /locus_tag="KRM55_003069"
     CDS             complement(9060..9428)
                     /locus_tag="KRM55_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1595281.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(9611..10270)
                     /gene="deoC"
                     /locus_tag="KRM55_003070"
     CDS             complement(9611..10270)
                     /gene="deoC"
                     /locus_tag="KRM55_003070"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBH1595282.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(10306..11493)
                     /gene="murJ"
                     /locus_tag="KRM55_003071"
     CDS             complement(10306..11493)
                     /gene="murJ"
                     /locus_tag="KRM55_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH1595283.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(11570..>12100)
                     /locus_tag="KRM55_003072"
     CDS             complement(11570..>12100)
                     /locus_tag="KRM55_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1595284.1"
                     /translation="GEFIENPKYFKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARL
                     QEHIANQRNDFLQKLTTKLIKENDIICIEDLQVKNMIKNHKLSRLISDVSWSEFIRQL
                     EYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINAS
                     RNILKEGLRLITIQNK"
BASE COUNT         4209 a         1857 c         1357 g         4677 t
ORIGIN      
        1 tattaattta tattaaatat ctactaactc aaatattcat aattaaactt taaactggat
       61 aaattttctt ttaagaatga aagtttatcc agttttgcga ttataataac cagttttaca
      121 tatccacttg taaaatatat ctaagcaata tatcatacta tatagattta tgagtgaaat
      181 aatatctgct atttactgaa tatttttatt tttcgttttt tagggggatt agttgtgttt
      241 aaagataaga ttgatgaatg tgttcatata atgactgcat atattgctag tttaaaagaa
      301 tactattcat tcatagaaac tcaaattggt gattttatta aaaaatatgg agaagatgtt
      361 gtagagttat gtctccatag agtgatgatt ctactatgcg aatgtggttt ggcataaaat
      421 taaatttatt aaaatgggta agaagaatcc tatataatat tcttcttacc cattttaata
      481 tatcaatttc atagcttatc gtttaaaata ttttacatcc attactagac aactttacat
      541 tctcttttta attctagtat atttaaatca ttttagttgc tccttattta ttcttattac
      601 ttgttttatt ttataaataa aataattctt tttaataatg ttttttgttg atattcctat
      661 cacacatcca attatttatc attgtcttga aattgtttgc atacttaatt taatccaatt
      721 gaaacacccc agcatagaat cccctgtaaa atagaagttg gattaaatcc taacatctat
      781 acagaaaata ctactccaag cacaagcaat ataatggaat atatttatca cttaattttt
      841 tatacttttt aaatcccata cctaaaacat taagtgcagc tattagaatt aataattgtt
      901 gtggtataaa attatgcttg cttcatattt attcattttt tactataaaa gttcttgttt
      961 tacaaaaaac atttgttttg tatcaaaata atacttataa attacataat tctcataaaa
     1021 atttctagta ttacttgtac tcttaataaa taatagccaa caagtacctt aaatcattat
     1081 atctatatct aataagaaac acagtaagat aattttttcg cccataactt aataaaaact
     1141 gttgatatta gtagcaattg aatttagtta atttatttat aatatacata aatttaaata
     1201 ttacgaataa agtattataa ataggatact ttctaaaggg aggaaattat gatagataat
     1261 caaaaatatg ttattttatc actagaatta catttatttt tttcaagaat tatgaaagag
     1321 catgctcttt ttttagaagc aggcttcaca aataaaaatt ataatcttgc tatggaagct
     1381 gaccactata aaaagcaatt tgaagattta ttatcataca ctgttagtgc tagtaatggt
     1441 ataattagac ctgatatatt atattcagaa gagcttgtaa ctactctcac atcagttgca
     1501 gaacaaaaaa cagaagagtt tacagggata gaaataaaca aaaacatcac tacaagagaa
     1561 ttaaatctac aaagtggtgt aaacccacaa gttggtcaag acttagtgaa ctatgtagct
     1621 caacttaact ctgatgcaat aagattactt gatgggctta ttaattttaa agaaagagtc
     1681 ttagatggtg tactatcatg tactatattt acatcaaact accctctact ccttgaacat
     1741 ataatacatg aagcaaattt atatcgttct tatgtagttg accttgaaaa taaaatagat
     1801 attgagtcaa aaaacgctaa agaaatagaa ttattctggg accatattat gatggaacat
     1861 gctctgttta tgagaggatt actagaccca tcagaaggtg aactaataaa tacttcaaat
     1921 gattttgcta taaaatttaa tgaattaatt gaaaaaacaa acgaaatgac tgattctaat
     1981 atcaagaaca ttacagaaga aactctaaat gaaactgttg agtttaaaga ttttaaagaa
     2041 gcaggagcat caggaataga acagtgtaag ataaaatcta taatattacc acttttagca
     2101 gaccatgttt taagagaggc aaatcattat attagaatat tggagagtta taaaaacatg
     2161 taattaaaaa ttacttttaa aataatcttt gcatatttag ataaaataaa ggtacagtta
     2221 actgtacctt tattttttat aaacttataa aatttaaaca agttattcat aaaataaaat
     2281 aataatcatc tataacccac aactttattt tatattaaat aaaaagtatt agtgattatg
     2341 ttttataagt atttctttat tcagttattt attaaaaact aatagtaaat cttatactaa
     2401 tcgcatattt atgttataac tatattgtaa ctattttcgt aatcttagga aaagattact
     2461 tataaaatta accttataca ataatatatc gtataatctt aattagcata atagttacaa
     2521 tattaaaatt taaatatggg agtgatttta gtatgataag acaaacacca ttagagaaac
     2581 gatatgacaa gctaggtcct catattgtaa cagcactcaa aaaacgttat tttgatgctt
     2641 attactgcaa aactagaaat gaagctttgc aacaaatttt agatttaatt cctcaaaatc
     2701 atgtagtatc atggggagga tctgaaacac ttaaagaaat gggcgtacaa actgctgtta
     2761 gagagaaagg atttaaagtt attgatagag atttagcaaa aactccagaa gaaagaactg
     2821 aaattatgcg tcaagcactt ctatgcgata cttttttgat gagtagcaat gcaattagtg
     2881 aagatggaca actctttaat attgatggaa atggcaatcg tgtagctgca atgatatttg
     2941 gtccaaaaaa tgttatagtt gtagctggta tgaataaaat tgtaaaaaac attgatgatg
     3001 caatacaaag aactagaaca attgcatctc cagcagttgt tcagcgtttt caagatgtca
     3061 atacaccatg ctatattaat ggaagttgta tagattgcac aagtcctgaa agcatttgtg
     3121 catacatggt tactacaaga atcagtcgtc cagcaaaaaa aataaaggta atattggtag
     3181 gagaaaatct tggtctataa aatatacata catgtaaata gctctataaa taataaaatc
     3241 atatgaaata acttatttct aaaagtggta gaataaaagc ttctacaaga ctttcattct
     3301 accactttta tattctttta atttgtgttt ctatattatt aattgctccg attttcatat
     3361 atattactaa ctatttttat tttcataatt tttttgttct tcatcaagct gtttataata
     3421 atctttatta tagtcagcta gataatctat accacctcct gtaatcacat ttaataattt
     3481 cattgcagat tcttgattaa ctttacaaac ataattatca ccagatttaa caagctctaa
     3541 tgtaatatta aattcttttt tctttgcaga atcaatatct ttcatagttg gatttggcat
     3601 catttctcct agtttaggag gattcttttt taaaatagaa accatatcag tattgttaat
     3661 ttttaaatct acagtcactt tatccttatt attctttata tctgaaattt cccaagtcat
     3721 atttttagaa tacattttaa atccttcttt atcttcgtat ataagattac ctaaccctga
     3781 ttttgggaaa tacttatcaa cagtatctgc atcttgtgtt tttattgaat taaacatact
     3841 atccacttca ttttttatct tattatcatt agtacaacca gctaacacca gtactgatat
     3901 tgcaaacatt ataatacata gaataaattt cttcattaaa ttatatcccc ctatactttt
     3961 ttgcacaaag attattctct tttttatctt ttgaaaaagt tgtagtaatt gcattttgtg
     4021 gacaaacttt tatacattca ccacacctaa tacagtctgg actatttaca tctttatata
     4081 ttggtatatc aagcttacat tttgtttgac atgctgtaca atttgtacat ttatctttat
     4141 caattttaaa tctatatatt gaaataggat taaaaaaacc atagattgct cctaaagggc
     4201 atatatactt gcaaaatggc ctataagtaa tgattgacat caataatatc aatagcaaaa
     4261 tacttaactt ccagctaaat aaaaatccta ttgattctct taaattctca tttcctaaaa
     4321 taagtggtat tcctcccaaa agtgttcctg aagggcaaat ccatttacaa aaccaaggat
     4381 ttccaccccc tgctacattt acaatagcaa ctggcaaaat aattacaaac attattaaga
     4441 ctatatactt tagatatttt agatatttat caccataaac tttttttatc tttactggaa
     4501 agggtacttt atgtagtaaa tcttgtacaa gtccaaaggg acaaagccaa ccacaaacaa
     4561 atctgccaaa aaaagcacca aatgccatta aaaaaccaac aacataaaat gagaatttat
     4621 actctctgct tgataaaact gcttgtaatg aacctattgg acatgctcca agtgcacctg
     4681 gacatgaata acaattcaat ccaggtacac ataatttttt actttctcct ccatatatag
     4741 ttccttctaa aaatccattt acatatccat ttgttaatgc tgtaaatgca acttgagtaa
     4801 taagtcttat attattattt actttagata ataacttcat tcctcttctc ctaaccaata
     4861 ccaatacact caagacaaat cataattgct ttagttaata ctgtatttgt ttctccacga
     4921 tatgtaccta atgcaataaa tataatacta attgcaataa tagaaatgcc ttttttatta
     4981 tctttaataa aattactcat tggcttttac catttttagt ctttcatcta taattttttt
     5041 ccaatcttcc ttactatttg cacctacaac cttctcaccc acaaagtttc ctttcttgtc
     5101 tacaaaataa gttgttggaa actccataac tcttttaaaa tcagtttttt taagttcttc
     5161 agatacagtc aattgttggt aagttgcatc tgactttttc ataatgtctt taactaaatt
     5221 tttctcttca tttgaaagac cagttctcat atcagtttta tcaacttcta caactaatcc
     5281 ctttatagct acattggaat tattactctc atattctttt gataatgctt caagctctgg
     5341 catttcaccc acacatggtc cacaccaagt agtccagaca ttaataagag taagttcttt
     5401 atttgaaaat atctcttttg ttaccttatt tccatcaaca tcctccgtat ctaaattact
     5461 aaaccattca ctattattct tgtttttttc tactggctta gattcttttt tgctacatcc
     5521 agaaatcata cctaaaacac aaatacatcc taaaactact atgaaaaacc ttttcatatc
     5581 tcacactcct agaatttata tagtatataa aatcgctgct tgaaataaaa ataacttatc
     5641 ttctatatta aagtaattat atttaataaa taagagctaa tttaaaaaaa gatatacagt
     5701 taaaatctat ttcttttcag acaaaatctt atatatatat aatagcttgt aaatcttaag
     5761 attatataca tatatttcta aagattttct taagaaacag ttagatttta ctaatataag
     5821 tttattaatt agcactatac taatttatct taatatgatt ttttgttgat tttaagctgt
     5881 ttatcgtata aataaaattt ttcttgacta tatagttact atatagctta ttatatatag
     5941 agagtaataa aaggaggtaa aatttatgga aaatttattt acaagaaaat tcactacttt
     6001 tgaatttcta aaatttgttt ctcctgcaat tatatccatg atatttatat ctttgtatac
     6061 aataatagat ggcatctttg tatcgacatt agttggttct gatgctcttg ctagtataaa
     6121 tattgtacta cctataatta accttgtttg tggatttgga ataatgatgg caactggtgg
     6181 aggtgctatc gtttctatac gtatgggtga aaatagacag gatgaagcca actctacatt
     6241 ttcttttata gttttgtttt cattgattgt tgggatttta ttcacagtaa tctcatattt
     6301 ctttatcaaa gaaatatcta ttttgcttgg tgcaacagat aagttattac catattgtat
     6361 aacttatggt aaagttatga ttttatgtac accattttat attttaaaat ttatatttga
     6421 gtactttgca agaactgatg gaaattctaa atttagttta tttctatcag tcattggtgg
     6481 tgtaacaaat ataatattgg attatgtatt tattaaatat tttggaatgg gtcttttagg
     6541 agctgcagtt gcaactgcta taggtattat tttaacttgt gttttaggta ttatttactt
     6601 cttatctaat aaatctacac taaaattaag aaaaccaaaa accgatttta gacttataag
     6661 agatactatg ataaacggtt cttctgaaat ggttacagaa ttatctacag gaattacaac
     6721 attcttattt aatgtagtag ctttaaaatt agcaggagaa aatggacttg ctgctcttac
     6781 tatagtattg tatgctcatt ttttaatgac atcagtctat ctaggattcg ctgctggagt
     6841 gtctccatta ataagctata attttggtgc tgaaaacagt gataaattaa aagaaacatt
     6901 taaacattct ctaaaattta tatttatttc ttctctttta gtgtttatta ttgctttagt
     6961 atttgcacca tttattgtta gggtctttgt aaatccagat aacacagtat ttaaactagc
     7021 cttacaagga ttaaaaatat ttgcatttgc ttttttgttt gttggtataa atatatttgc
     7081 atcaggattt tttacagcat ttcacaatgg aaaaatttca gctattatat cttttagtcg
     7141 tgcctttgtt tttataatca taggaatcat aattcttcct cctatgttaa acatgactgg
     7201 attatggctt acagttccat ttgctgaggt tataaccata tttatatcta ttctatttat
     7261 aaaaaaatat aaatgtagat ataagtatta aaaattaata cttaaaatca acatttatta
     7321 aaactaataa acctgcttta aaatacaaat ttacaaattt gatttttaag caggttttat
     7381 tttagttata ataagtcatt tgcatactct ttaattggtg cttttctaag taataaaatt
     7441 ataaatatta tgcaaataac tataattcct acctttgttc caaataaaat aaaaggattc
     7501 tgaaatgaat aaataatttt ttctaaatac aatagcattt tatgcatatt tttagttgca
     7561 aaattaacta tataaattac cattaatatc ggtaatccta tcaatatagt aatactagta
     7621 acttttctaa ctctatatgt aaaagctcca agtaacactc ctataaaacc tatacatatt
     7681 tcatttatac atatttgtac aaaataattt aaataagtta gtggcatact tgatgttgaa
     7741 ggatctatca gtgctgatat agatgtccaa atcatatctc tctttagtaa aactgatagt
     7801 tctatactgt aacctgttat aatttctata aataacttcg ataaaaaaat caaaactata
     7861 cctaaaatag aaatcacaaa gcttaaaata attaaatcta tgacaatagc ttttatacaa
     7921 ctttttctat ctgctcttat acttaaagct cctgaaaagt ctttatttgc tatatttact
     7981 ccatacacaa atagcagtat agttatatat gttaaaatag gattcacaat cgtggataaa
     8041 ttagttttag atgcttctcc aaaaatcttg agaataaaca ctggcaaaat attcataaca
     8101 attcccacaa tcataaatat aattatatac aatttagtat ttttattaaa aaattttata
     8161 tatggcttta attcattcaa ttacaattcc tccttcttag tcatgttaac aaacatatct
     8221 tgtagcccta tgtatcctac atcaatattt gaatttttaa gtattttttc atcattttca
     8281 ctaaaatcac catagtaaaa ataagcaact gcatttccaa atgccttttt aggttttata
     8341 ttttttatac attctaattt ttctaactct tctttatttc cagtaatata atgagctttt
     8401 tgttttatga catcaatttc ttcatctata ataatttttc cctcatttaa tattattaca
     8461 tgctccagta aatcatctat ttcatcaatc aaatgagttg atattattat tgtccttgga
     8521 ttttttatat aactatctaa aattatgtta taaaactctt gtctatttac tgcatccaaa
     8581 ccaattgttg gctcatcaaa tatggtgata gctgaattag aacaaatacc tattatattt
     8641 gaaagtatag ttttcatacc tcttgacagt tgtttatact tttttttagt atttaaatca
     8701 aaatatttgc ataattcttt ttctaagcct ttatcataac ttttataaaa actagaagaa
     8761 aattcaaata tctgacctac tttaaaatct ggactataaa attctttttc cctgacaata
     8821 caaacttctt ccaaaacttt tatatcttct tttgggttct ttcctaatat ttctatctca
     8881 ccttcatttt gaattaactg atttaccatt atatttaata atgttgtttt tccagctcca
     8941 ttcttaccta ataaaccata tatcttattt ttttcaaagt ttagagacat attattaaaa
     9001 atattttgct tcttaaaact gtgagataaa ttttctatct taatagaact actcatatat
     9061 taatcctcct tgaaattaat tataatatca accaattctt ctctatttat ttctaatttg
     9121 ttagcttctt gaagtaggtt ttttacaaaa ttatgtttaa aattttcttt tctagcttct
     9181 tttataatag tttttgcacc atctgataca aacatcccta tccccctctt cttatataaa
     9241 atatttttat caaccaatat atttatacct tttaatactg tagctggatt aattttataa
     9301 agctttgaaa gctctgttgt tgatggaacc tgttcttctt cttttattcc atttgatagt
     9361 atctcatctt caattgctcg tgctatctga ataaatatag gttcttcatt atttaatact
     9421 aatttcatag gttcctcctt tctccattag ttagttactc aactaattaa ctatataact
     9481 tataatatct tgaaaaatat tttctgtcaa tactaaataa aaaacagagg gaaaattccc
     9541 tctgtttttt gttctttata tttataatta aattttgatt tttgtaatcc tatcccataa
     9601 gttaaaaact ttaataatct gttgtatctt cattttttaa tattttacat attgagctag
     9661 ttcctaacct ttctgctcct gcctctataa atttttctgc atcagaaatt gatttaactc
     9721 cccctgcagc ttttattttt acattttttc caacatgctc tttcataagc tttatatctt
     9781 ctaaagtagc tccacctgtt cccattccag tagatgtttt tataaaatct gaacctgaca
     9841 ttgttactat ttcacacatt tttatttttt catcttcatc taaataacat gtctctataa
     9901 tgacttttaa tactttatct cctatagctt tttttatttc ttttatttct tttcctatat
     9961 tatcataatc tttatttttt atatctgaaa tgtttacaac catatcaact tcatctgctc
    10021 cattttcaat agcatctttt gcttcaaata cttttgtagc agtagtttga tatcccaaag
    10081 ggaaccctat cactgtacat atctttattt taccttttag atattctgat gctcttttca
    10141 catatgatgg tggtatgcaa actgatgcta cactcatatc tacagcttca tcacataaaa
    10201 ttttaatatc ttcccatgta gttgtagctt ttaaaatagt atggtctact gtttttaata
    10261 tatgtttcat aaaatcctcc taaatttata attaatataa ttagattact tttttaaatg
    10321 caattttctc tttgcaatat tcagtatcat atcaacctct tcaactttaa aaatagtcat
    10381 tagtagtgta taaattccac ctccaactat aactgaaata gctagtgaga caaactcatt
    10441 aaatgttcct actcccaaaa ttccaaatat aaatttatac gtaaagtatg ataaaacacc
    10501 cataattaaa gatgcaacta ccgatttcaa agttgctttt attattttat cttgtccaaa
    10561 atatccaact tttctcttta ggttcaagaa gagtaacaat atacatgcaa ttgatgatga
    10621 actagttgca agagcaagac caccatgagc cattggtttt attaaaacta agtccaatac
    10681 tatatttacc cctacagata taatcccatt taccataggt gtttttgtgt cttgtaatga
    10741 ataaaaaacc tttcccaaaa tatctcttaa gccaaatgca gtcataccaa ctgcataaaa
    10801 aattaaggca gttgctgtca tttgggttgc cctcgcatca aaagcacctc tctcaaaaat
    10861 gattctaaca acaggagttg caaaaaaaat agaagcaact gaaataggaa tcatagaaat
    10921 tattatcata tttatactag atttaactga actagtaaac ttcttttgat tattttctgc
    10981 acttaactta gataacatag gatacataac agatactatt gaagctgtaa atgtccctgt
    11041 aacaaaacca tttaatctat ctgcataagt aagtgctgga atgcttcctt taactaatgt
    11101 tgaggctaaa gttgtatcta ccaatgagtt cacttgatta acagcaacac ctataaatac
    11161 tggtgaaagt aatgctagta atttaataag gctatcatct ttaaagttta agtagtataa
    11221 gtatttgtag ttcgtttttt taacaaaaaa catgtaaaag agcagttgaa ctaccatagc
    11281 aaccacagca ccaattggaa gtatgtatgg tccaaatatg gtacttaaca ttattgaaat
    11341 aattattact atattatagg gtatacttcc aaatccaact acaataaagt tctctttaat
    11401 ttgtaaaaat gctgacataa cacttgtaat acctatgaat attattcctg ttctgaacct
    11461 cccatgacta aagtcacagg gttcctgctt catagaattt tgcatactaa aatatgtctt
    11521 actaattctc cacaggctat ccccgtagtt cctacggttc ttacatacgt tatttatttt
    11581 gaattgttat tagtcttaat ccttctttta atatatttct acttgcattt atatctctat
    11641 cgtgagtttc attacaacta ggacaaatcc attctcttat atttaagttc ttaacttcct
    11701 cgtttttata cccacattta ttgcatattt gtgaacttgc aaagaattta cctaccttta
    11761 caatttgtct accatgccaa ttagccttgt attctaattg acgaataaac tctgaccatg
    11821 atacatcaga aattaagcga gatagtttat gatttttaat catattcttt acttgtaaat
    11881 cttctatgca aataatatca ttctctttta ttaatttagt agttaatttt tgtagaaaat
    11941 catttctttg attagctata tgttcttgaa gtcttgcaac ttttaatctt gctttatttc
    12001 tatttaaact accgattgtt tttctcgata attctctttg taatttagca agtttgttta
    12061 atgacttctt aaaatactta ggattttcta taaattctcc
//
LOCUS       DAEPXW010000108        11839 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.111, whole genome shotgun sequence.
ACCESSION   DAEPXW010000108 DAEPXW010000000
VERSION     DAEPXW010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11839
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.111"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            197..1237
                     /locus_tag="KRM55_003073"
     CDS             197..1237
                     /locus_tag="KRM55_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1595285.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1593..2915
                     /locus_tag="KRM55_003074"
     CDS             1593..2915
                     /locus_tag="KRM55_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH1595286.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3212..4573
                     /locus_tag="KRM55_003075"
     CDS             3212..4573
                     /locus_tag="KRM55_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH1595287.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4646..6040
                     /locus_tag="KRM55_003076"
     CDS             4646..6040
                     /locus_tag="KRM55_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1595288.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6102..6572
                     /locus_tag="KRM55_003077"
     CDS             6102..6572
                     /locus_tag="KRM55_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBH1595289.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6575..8791
                     /locus_tag="KRM55_003078"
     CDS             6575..8791
                     /locus_tag="KRM55_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1595290.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            8874..9545
                     /locus_tag="KRM55_003079"
     CDS             8874..9545
                     /locus_tag="KRM55_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1595291.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            9908..11122
                     /gene="dpaL"
                     /locus_tag="KRM55_003080"
     CDS             9908..11122
                     /gene="dpaL"
                     /locus_tag="KRM55_003080"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH1595292.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            11249..>11839
                     /locus_tag="KRM55_003081"
     CDS             11249..>11839
                     /locus_tag="KRM55_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1595293.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT         4477 a         1358 c         2401 g         3603 t
ORIGIN      
        1 ttgcttattt aatagaggat ttttgtaaaa tgaagaaagt atatctatca aattaaaact
       61 aagtagatat actttttatt aagttttgtt ttaaaataat attattaaat tataactaag
      121 cttttctgtt atgatataat taaatagata atgtgaatga ttattatata gaatacttat
      181 ttggagttga tattttatgg acaaacacag tgattcagta atgtatggtg gaatggaagt
      241 atataatatt tggggaacaa caacagtaga ctccataatt ggagagtctg atgtaatgcg
      301 tgctcttaag aatagaattt gtaaaattgg aaatagtgat tctactgtag ctataactgg
      361 agaaagtggc actggaaaag aattaatagc aagagccatt catctcgcag gaaacagagg
      421 gaataaaaca ttcgttgcta taaactgtgc tgctatacca gaacctttac tagaaagtga
      481 actttttgga tatacaaaag gagcttttag tggagcagat tcaaaaggta aaattggtaa
      541 gtttgaattg gccaatggag gggttgtatt tttagatgag ataggagata tgccaattca
      601 actacaatca aagttattga gggtattaca ggaaaagaag tttacgagaa taggttcaaa
      661 tgaactaatt gatatagatg ttagaatcat atcagctact aatagagatt tatttgagtt
      721 ggttaaggaa aataaattta gagaagactt atactataga ttgaatgtaa tacctttaga
      781 agtgcctcca cttagagaaa gaggagacga tatacaaata ttaataaaca attttataga
      841 caaatattcg agaaagatga agaaaaacgt gtaccatata gagccagatg tggaacaaat
      901 gttgcttaag tatccttggc caggaaatat tagagagttg gaaaatacta tagaactggc
      961 attaaacctt cttgaggaag atggaataat acataaagga ataataaata gaaagatact
     1021 tgaatatttt aagttaaata atataaatat aaagttactt gaggaaagtg actatgagat
     1081 aagtatggaa caagacatac ttacacttga agagtttgaa agagcctata taaagaaagt
     1141 gttaaagttt tacggaaatg atactaagtc taaaaaacta gctgccaaaa aacttggaat
     1201 atcactagct acattgtaca gaaaaataga tgtataataa ttaggctttt tattctcaat
     1261 tctaaaattt gaaattataa aattgataaa aaacacttgg aaaactattt tctaagtgtt
     1321 tttttgtgta atagcatttt attatccaaa aataaaaaaa atttaaaaga atttaaaaaa
     1381 ataaatgctt taataaatta tcaaatacta acaaatataa taaaaattat atatgtaaaa
     1441 caattatgtt aaaaaattgg cattataatt gcttcatatt aagttgagat gacaaaataa
     1501 aaaaagaaag gatgttgtgt gagataataa taactgtcat taaaaaatag ttgggagtga
     1561 taaccttgag taaatatcaa aagaatgttt ctatgtttga tattgatgga aggccaccaa
     1621 ttttaaagtg tttgccacta tcaatgcaac atatactagc aatgatagtt ggaactgtta
     1681 cagtacctat agtcgtagga ggagctgtgg gtgttagccc tacacaaata acacttttag
     1741 tgcaatatgc attaataata gctggtatat caacacttat acaactatat ccaataggaa
     1801 atattggttc aagattgcct ataatttttg gagttggttt tacttatgta ccaacacttg
     1861 tagcagtcgg aggaaattat ggattagcaa gcattttggg tgcacaatta atagggggag
     1921 tggctacagt attaataggg atattcataa aaaagataag aaaatttttt ccgaatatag
     1981 ttgcaggaac agtggttttt acaattggat tatctttgta tcctatagca ataaattata
     2041 tggcaggtgg tgtaaatagt cctacttatg cctctatgca aaactgggca gtagcggcta
     2101 taacattagt ggtagttata ggtcttagtc aatttgcaaa aggatatgca aaattggcag
     2161 caatattttt gggaattata gttggatatt gtgtatcttt agttctgggt ataataaatt
     2221 ttgaccctat tagagaggca acttggtttg cgatacctaa accgcttgaa tttgggatgg
     2281 aatttgatat gcctgtaata atctcagtag taattgtaag tataatcaat gctgttcaag
     2341 caattggaga tttatcagct actacaatgg gaggcatgga taggaatatc acagataagg
     2401 aattatcaag tggagtaata ggaagtggaa tttgtactat gataggagct ttgtttggag
     2461 gtttaccacc atcatcatat agccaaaacg tggggatggt agctatgaac aaagtaataa
     2521 gtagatttgt gcttggaata gctggtatat ttatgttatt gtcggggttt gtgcctaaat
     2581 ttggtgcact aatgactact ataccatatt ctgttttagg aggagctaca atatctatat
     2641 ttagtatgat aacaatgaca ggtataaagt taattattac agaagagttg tcatcaagaa
     2701 atattaccat tgttggtttg gcaattgcct taggcatggg aataacatca gtaccagcag
     2761 cccaagaggc atttccttca tttgtaaagt tagtatttgg agaatctcca atagtaattg
     2821 caacattggt tgcattcgtt ttaaatctaa taataccaaa taaaagtcta gaggatgagg
     2881 ctaaagaaag agctgttatg gaagagacta attaagatat aataatttaa aagaattgtt
     2941 taaattattt agtatgagat tgttagatta tttttgatag ctattcattt taataaaaaa
     3001 tttaacaaat aaatatatac caggcaatta atgttcattt aagttgaaaa tcggggaggg
     3061 aatatttaga aatttgttaa ttttttataa aaatagctca gtttagctgt gtttatcggt
     3121 tgagcaataa attcatggtc ataaaaatat ttatagaaaa taattataaa aatatttagt
     3181 caagatattt atgtatggga ggatttattt tatgaaaaca cgtaatactt caaaatatga
     3241 tgtcgatggg ataccaccac taaaggaatc aatacctttg gccttacaac atctgttagc
     3301 aatgatagta ggaaatatgg tacctgcgat attaatagca aacgtggtag gacttaacca
     3361 ggggcaagca acaatgttga ttcagggttc tatgttagca gcaggtttag caacgttttt
     3421 acagttatat ccaatacctt tatttaaagg atttaagtta ggttcaagat tacctgtaat
     3481 gatgggaatg agttatgtat ttttaggagc ttgtctttca gtagcagcta aagatggttt
     3541 agcagctcta tttggagcac agattgctgc tggggtaatc gtattctttg taggatttgg
     3601 agttaagaaa attagacata tattcactcc aatagtttct ggaactataa tagcatgtat
     3661 gggacttgga ctattcgcaa cagctataaa gaatttagct ggaggagaag gcacacaaac
     3721 atttggaagc ccaataaact tcacagtagg agttatagtt gcttttgtaa taataatgat
     3781 aaataaatac ggtaaaggtt tagtaaaaaa ttcttcaata ttaataggaa tattagtagg
     3841 ttatgctata tctttagttt taggattggt tgatttctca gccgttcaag gagcagctat
     3901 agtatcttta ccaacaccag cagcttttgg attagaattt agaccagagt taatagtaat
     3961 gtttactatt atttacataa taggtatagc tgatatgatg ggtgcctgta caatagctac
     4021 agtaggagca atggatagag aggtaactga cgaagaatta gcatcagttg ttttaggaaa
     4081 ttctataact tctataattt catcactatt tgcagctctt ccaactggag tatttagcca
     4141 aaatacagta attgtatcta tgaacaaagt tacaagtaga tttgtaatag cactaggggc
     4201 acttgtatta ttactagcag ggatatctcc agcattgggt gcaataatga caactatacc
     4261 atcttgtgtt gttggtggag caactttagt agttttctca tcaatagcaa tgtctggttt
     4321 ctctattatg agtatggatg gattcactga agaaaacaat cttatagcag gtgtatctat
     4381 agcaacaagt atgggtctta caactgctcc acaagtttta gaccaattcc cagaaacaat
     4441 tggaactgtc cttggagggt caagtatagt ttctggagca ataatagcta tattacttca
     4501 aacattattt aaattaaagt cacgtaaaag tgctgaaaac gttacttcaa atcttgagga
     4561 aaatattgga taaatgtatt agatataata tgagaaaacc atatggtaaa atgttgtaat
     4621 gaaagtattc aaagggggat ttaagatgat tgatatacta ataaaaaatg caataattgt
     4681 tacagttaat aaagacagag atgttatatt tgatggagca atagctattc aaggtgacag
     4741 aatcttggac ataggaaata cagttgatat tgagcctaag tatcttgatg ctaaaaaagt
     4801 tatagatgct aatggaaaag taatattccc tggctttata aatactcata atcacctgtt
     4861 ccaagtgtta ttaaaaggtt taggtgatga tatggcactt catgagtggt taaatacaat
     4921 gatgtttcca tcagcaaaat tcttaacaga acaagatact tatgatgctg caatgcttgg
     4981 atgtatggaa ggtttaaaaa gtggtataac tacaatggtt gattatatgc atactcacaa
     5041 tagaccagga cttacagatg gaatagtaaa ggcatataaa gatttaggta taagaggggt
     5101 tgtaggtaga ggttgtatag atttaggtat tcacaaagag cttatagaag atgtggaaac
     5161 ggttgaaaaa gatttgagaa gggtattcga aaaatatcat aattcagaaa atggaagaat
     5221 aaaaatctgt gtagctcctt cttcaatgtg ggctatatct gaagaaatgg gtaagatgct
     5281 ttggaatata gttaaagaat atgattcata ttttacagtt catatatctg aaacagaatt
     5341 tgcaagaaca gcaacaaagg atatacatgg agaaatagat ataaaattac ttgaaaaatg
     5401 gggtatagta ggtccagaag ttgtagcagt acattgtgta tgtataactg atgaagacat
     5461 ggaaatgctt aaaaagtatg acataaaagt ttctcataat gtagcaagta acatgtatct
     5521 tgcttctggt gttgcacctg tgccagaaat gttaaaaaaa ggtataaatg tgagtttagg
     5581 tcttgacggt gcagcaagta ataacgcaca agatatggta gagcttatga aattaacagc
     5641 tttacaacac aaagtaaata attgtgaccc tctggcaatt tctgcagaga aagttcttga
     5701 aatggctaca attgagggag caagaactct tagaatggaa gatgaaatag gttctttgga
     5761 gattgggaaa aaagctgacc tagtaatatt taactcaatg ctttctccaa aatcaatacc
     5821 tcttcacaat cctgtatcaa ctttggtata ctcagctagt atgcacaatg tagagagtgt
     5881 tttagttgat ggaaatgtaa tacttgaaaa tggaaaagta actacaattg aaagtgaaga
     5941 acaagtgttg cttaatgcac aacatgcagc agaagaatta tgtaagagag ctaatgtaac
     6001 taatagaatg gaaggacata agtggaatag cttatactaa tattaaaata agattgtaat
     6061 aatattctat tacaacatta gtttatctgt aggaggagaa aatggaaaaa ataaaattaa
     6121 atattaatga ttacatgtat gaaatagaag ttgaaaagaa tgaaactctt ttgcatgtac
     6181 ttcgtgaaaa attaaatcta actggagcga aacaaggttg taatagtggc agttgtggag
     6241 catgtaaagt tttgatagat ggagttgaca tgaaatcttg taaacttctt gcaaaaaact
     6301 gcgaaggtaa agttatatac actatagaaa gttttgctaa tggagaaaat cttcatccaa
     6361 tacaagaagc ttttatagaa gtcggagctg tacaatgtgg atattgtact cctggtatga
     6421 ttataacaac acaagctctt ttaaatagaa atgcatctcc taatgaagat gaaattagag
     6481 aagcttttaa agaaaatctc tgtagatgca caggatatgt aaagattata gaagctgtaa
     6541 aattatctgc agctagatta gggggtagat aattatggaa aaggtaatag gaaaatcata
     6601 ccctctaaaa gatgcagctt taaaagttac tggtcaaatg aaatacgtgg ctgatatgaa
     6661 accacaaaat gtactttacg ctaagatgct tttaagccct gtagcacatg caaaaataaa
     6721 aagtatagat acaagtgaag ctgagaaagt agtaggtgtt agagctatag ctacttatct
     6781 caatacatca caaagaaaat acaatggttc attaagattt tatgagcaca aaatacctga
     6841 aaatgaagtt atattttcag atacagttag atttgttggt gaccgtgttg cagcagtagc
     6901 tgcagagact ccagaaatag cagagaaagc tgtaaaactt ataaaagttg aatatgaaga
     6961 attgccagct gtatttacta tacaagatgc aataaaagaa gatgctatct gcatacatgg
     7021 agattcaaat atagtttctc aaaacaacat aaatggggga gatgtagaaa aaggcttcaa
     7081 ggaatgtgac tatatatttg aagatgaata ctctactcca gcaatacatc atagtgcaat
     7141 agagactcat agtgtaattg cacactatga ttataatgat aaattaactg tacatacacc
     7201 ttgccaaaat acatttggat ttagaataat actatctcaa atttttggga tgtcattaaa
     7261 taaagtaaga gttataagac ctgctattgg aggctcattt ggtggaaaat tagaacttac
     7321 aattgaacca gtagcagccg cattatcaaa aatgacaaga agaccagtta aaatggttct
     7381 tacaagaaaa gaatctatga tatcgacaag aactcgtcat gggtcttttg taaaattaaa
     7441 aactggtgta aataaagatg gtgaagtaat agcacaagat ataaaaatat atacaaatac
     7501 aggagcatat gcatcaagtg ctttaaatgt tataggagca cttagtcata aagtatttaa
     7561 agtttataaa ataccaaata taaagtttac tgggatgcct gtatatacaa atacaccaat
     7621 agcaggagct atgagaggct atgggtcacc tcaaatattt atggctcaac aagctcaatt
     7681 tgcgaaaata gcaaaggaaa taggtatgga tttagtcgat tttcaaaata aaaatgcagt
     7741 agagccagat gatgtcgata taatcttcca cggttctctt ggaaatccta gagtattgga
     7801 ttgtatagag caaggtaaga agatgtttaa gtgggatgaa aagaaaaaac ttccaaaaga
     7861 agaaggaaaa tatttaagag gtataggtat ggcaataggt gcacatggta atggagtttt
     7921 tggtgcacat agagatgttg ttacattgac tcttaaatta aatgaagatg gtacgttgac
     7981 actactaaca ggagctcatg atatgggtaa tggtgttgta actatgcaaa caatgatggt
     8041 agctgaagtt ttaggaataa cacctgataa agttgataca tttgaaactg atacggatgc
     8101 atgtacattc aaccttggtg actatgcaag tagaggggta tttgtagaag gtggaggagc
     8161 taaaaagaca gcagagaaat tgaaaaatct tatattagaa gaagcagaaa aattacttga
     8221 aacatcaaaa gaagatttat acctagacaa tggatgtgta attagtaaac ttgatgaaaa
     8281 tgtaaaagca tcactttctg atgtcgcagt atatagtcaa agtaaatcat taagagagtt
     8341 aactgttgtt gaagattatt cttcaccagc tggacgtact tcttatggtg tacattttgc
     8401 tgaagtttta gtagataaag aaactaagga tataaaagta gttgattttg tagctgtaca
     8461 tgatgttggt agagttataa atcctctaaa tttagaagga caattagaag gtgggattca
     8521 tatgggtcta ggatacgcat tgagtgaaga attggcattt gatgaacaag gtagacctaa
     8581 agctactgat tttaaaacat ataaattatt tagaactgta gatatgccaa aatgtcaagt
     8641 tgcatttgta gatggttatg aaaaagctgg gccttttggt ggtaagagta ttggagaatg
     8701 tgccgttgta ccagttgcgc cagctgttgc aaatgcagta tataatgcaa ctgatgtaga
     8761 gatacattca ttaccaataa aattaaaata gtagaaatta aagcagaaat aataatttat
     8821 tgtatttgta aatagataat aaaaatagat ttatttggtg aggagatatt attatggcaa
     8881 agatattagg tatttgtgga agtccacgta aaggagcaac agaatatgca gtgttagaag
     8941 ctttgaaaga agcagaaact atacctggta tagaaactga gtattggtca gttagaggga
     9001 aaaaaataag tccttgtgta cattgtgatg catgtataag aaaagaaact atgtgtatta
     9061 taaaagatga tatccaagaa ttagagcaaa aaatattgga ggcagatgga attatagtag
     9121 gttctccagt ttatgatatg aatataactg ctcaacttac agcagtattt aatagacttc
     9181 gtccaatgta tttagttcat ccaggaaaac ttcaaaataa ggttggtgca gctataacga
     9241 ctggtggaac tagatatggt ggccaagaat tgacaaaact tcctataata aatttcttcc
     9301 taatgcatga aatgttagtg tctggaggtt taggtggatg ctatataggt ggtacaatat
     9361 ggagtaaaga tggaaaagca aaaggtgccc aagaggatga gacaggtatg gacacagtaa
     9421 aaagacttgg aaaaggtgca gcagaggcag ttatggtttc taagtttggt cttgaaaaat
     9481 ggaatgtcgt aaaagaagaa ttagatgtta aaaaagatga aaaatcacct cttagagacc
     9541 actaaagatt tattatatta ttgaatatat acaaatagtg atgtaataga ttattgcatc
     9601 actattttat gttttaattt agattttata gattttatat taaaaaatat agaaacaaag
     9661 tgttttgaga tttattttta aattttaaaa atgagaatta aaaagtgaga agatagaaaa
     9721 ggttttttag ttattaaatt ctacatacat tgtatgaact aaagatagaa aagaaaaaat
     9781 aataaaagca ttgcaatttc tatactaaag agtcatagaa aaatatctag tatatattta
     9841 gtgttggcat gttaattgct tatatattaa agtataaaaa tttaacaata atttggaggt
     9901 attttagatg ttaaaagaaa ttaaatggaa agtaaataat ttgccaaagg gcgataagga
     9961 aaattgtatc aaatttttaa atgaagaaga aataactaag gttagaaatt ttcacaaaag
    10021 ctttcctcaa tataaagaaa ctccattagc aaacctagaa ggtttagcaa aaaaattagg
    10081 tgttgcagga gtatatgtaa aagatgaatc ttatagattt ggattaaatg catttaaagt
    10141 attaggtggt tcttattcta tgggtagata cttagctcaa agattagata cagatatatc
    10201 tgagttaggg tatgacaaat tgacttcgaa agaaataaaa gaaaaattag gagaaataac
    10261 tttctttaca gctacagatg gaaatcacgg tagaggagtt gcttggacag ctaataaatt
    10321 aggtcaaaaa tctgttgtat taatgccaaa aggttcttct gaatttagat taaataaaat
    10381 taaaggagaa ggtgcagatg ctagtataac agacttaaac tatgatgatg cagtaagatt
    10441 agctaatgat tatgcagaag ctgatgacca tggagtaatg gttcaagata cagcatggga
    10501 cggatatgaa gaaataccag catggataat gcaaggatat ggaactatgg ctcaagaagc
    10561 tatagagcaa ttaaaagaat atggagtaga tagaccaaca cacgtatttg ttcaagcagg
    10621 agttggttca cttgctggtg cagttcaagg gtatgttgct tcaatatatg atgaatgccc
    10681 aataacagta gtagtagagg ctgatgaagc tgattgttac tataaatcag cagaagctgg
    10741 agatggaaaa ccaagatttg ttggaggaga tatgccaact ataatggcag ggcttgcttg
    10801 tggagaacca aatactatag gatttgaagt attaaaaaat catgcagcag catttgtttc
    10861 agcaccagac tgggtttctg ctaaaggtat gagaacatta ggtaatcctt taaatggtga
    10921 tgaaaaagta atttctggag aatctggagc agttacaact ggtcttttag tagcagctat
    10981 ggaaagagaa gatttagcag atttaagaaa agatttaaaa ttagatgaaa attcaagaat
    11041 acttttaata agcacagaag gagatactga ccctgacaaa tatagaagta tagtttggga
    11101 tggagaatat ccaagtatat aaggaattac taaaatgcaa ttattagata ttggtttaca
    11161 tatttagaag atatataagt tctaaaattt agaaaatata taagtatata aaatacatac
    11221 attataaaaa atctaggggg ataatgaaat gttaaacgaa caaagaaaac aagaagtaac
    11281 tgaaatatgc caaaaattaa ttcaaaatcc tagttcttct ggaaatgaag aaggtgttgt
    11341 aaaagcaata gaagagtctt ttgaaaaatt aggttttgat agttggtcaa gagatagata
    11401 tggaaatata gtaggatgta taaaaggtaa caagccaggt aagaaaatat tatttgatgg
    11461 acatatagat acagttccag ttccagatgc aagtaaatgg agtgttcctc cttttgaagg
    11521 aaaaatagtt gatggaaaga tatatggtag aggaacttct gacatgaaag gtcaatatac
    11581 tgcaatgatg tctgctgtag cgtattttgc taaagacact aatagagatt ttgctggaga
    11641 actatatgta gcaggtgttg ttcatgaaga aatatttgaa ggtgtttcag ctagagagat
    11701 aagtaaggct gttcaacctg actatgttgt aataggtgag tcttcagagt taaacttaaa
    11761 gattggtcag agaggtagag gagaaatagt agtagaaact tttggtaaac cagctcactc
    11821 tgctaatcca gaaaaaggt
//
LOCUS       DAEPXW010000109        11775 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.112, whole genome shotgun sequence.
ACCESSION   DAEPXW010000109 DAEPXW010000000
VERSION     DAEPXW010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11775
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.112"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(423..1139)
                     /locus_tag="KRM55_003082"
     CDS             complement(423..1139)
                     /locus_tag="KRM55_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595294.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(1678..2478)
                     /locus_tag="KRM55_003083"
     CDS             complement(1678..2478)
                     /locus_tag="KRM55_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH1595295.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(2792..3523)
                     /locus_tag="KRM55_003084"
     CDS             complement(2792..3523)
                     /locus_tag="KRM55_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595296.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNSHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(3510..4205)
                     /locus_tag="KRM55_003085"
     CDS             complement(3510..4205)
                     /locus_tag="KRM55_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1595297.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(4207..4998)
                     /locus_tag="KRM55_003086"
     CDS             complement(4207..4998)
                     /locus_tag="KRM55_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595298.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFLSLTCLMLFEIFFNREVDKN"
     gene            complement(5008..5820)
                     /gene="modA"
                     /locus_tag="KRM55_003087"
     CDS             complement(5008..5820)
                     /gene="modA"
                     /locus_tag="KRM55_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1595299.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(6455..6655)
                     /locus_tag="KRM55_003088"
     CDS             complement(6455..6655)
                     /locus_tag="KRM55_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1595300.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(6880..7056)
                     /locus_tag="KRM55_003089"
     CDS             complement(6880..7056)
                     /locus_tag="KRM55_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595301.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(7110..7199)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(7379..7579)
                     /locus_tag="KRM55_003090"
     CDS             complement(7379..7579)
                     /locus_tag="KRM55_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595302.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(7581..7931)
                     /locus_tag="KRM55_003091"
     CDS             complement(7581..7931)
                     /locus_tag="KRM55_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBH1595303.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            8093..8282
                     /locus_tag="KRM55_003092"
                     /pseudo
     CDS             8093..8282
                     /locus_tag="KRM55_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8759..8929)
                     /locus_tag="KRM55_003093"
     CDS             complement(8759..8929)
                     /locus_tag="KRM55_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595304.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESGYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(9318..9812)
                     /locus_tag="KRM55_003094"
     CDS             complement(9318..9812)
                     /locus_tag="KRM55_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1595305.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKSDYGSSIDIMNEQNKIDIVIKFLND
                     KSNT"
     gene            10617..10994
                     /locus_tag="KRM55_003095"
     CDS             10617..10994
                     /locus_tag="KRM55_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1595306.1"
                     /translation="MKEEILIEKLLRVELIVMEYLWKKDTLMPKKKIVKEIKQIYGWH
                     KSTIKILLKRLVDKRYLARYIINFQSYYKIIIDNKEYYTFKKKVLKSSKSIKIMHSLT
                     TIHKNVSKEKLDLLDEYYRNLKE"
     gene            11099..11474
                     /locus_tag="KRM55_003096"
                     /pseudo
     CDS             11099..11474
                     /locus_tag="KRM55_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT         4432 a         1517 c         1381 g         4445 t
ORIGIN      
        1 taattataaa attgtagatt attaaattag tgttgtaaaa cattttatta cttgtaaatg
       61 catgaaacct taaggttaat agtatcaaag ttaatataag tgtaagttct atttttacct
      121 tagaaaaaag gtttatgaca ttctctaaga atttgacttt agtttgttta ttttttttat
      181 acaatgtaaa acatagtata gtcaataaaa aacttgataa tataatacct atgcagacaa
      241 actctaattc tacttttgac aaatgtacag gagtaccgaa aaaataaaaa taagggagag
      301 caaactctct ataataataa ttaatattag aaaagttatt attcaaatca taaactgctt
      361 caaataatat agaaactaat agaaacagta ataataataa aataaatttt gctttagaat
      421 cattaataat taagtttttc aattttgtaa ccaatgcccc acaccacctt taaatatttt
      481 ggttcttttg gattaatttc aatcttttct ctaattcttc taatatgaac agcaatagtt
      541 ctctcacaac tataagcatc ctcattccag acattttcat aaatctcatg agaagagaaa
      601 attttacctt ttcgtgacat aagaagtgta agtattttat attcaagtgg tgtcatttta
      661 atttcctcac catctaaaga aactattttt gtatctgtat ttagctctag gccaccactt
      721 tttagaatat aattagtatc atttgagtta tttgtattac taaaatcacc taaatttata
      781 taccttctaa gttgagattt tactcgagca gtaagttcta gtggattaaa tggtttagtt
      841 atatagtcat cagcacccat attaagacct ataattttgt ccatatcttc tgattttgca
      901 gataagagaa ttattggtat attccttttt tctcttattt taagtgtagt tttaagccca
      961 tctaaattgg gcatcattac atccattatt attaatttaa tatcattttc gattagtatg
     1021 tccaatgctt caagtccatc atatgccttt aaaacattaa agttatcagg tctcaaatag
     1081 aactctatag catcaactat ctctctatca tcatctacaa ccaatatatt ttgattcaat
     1141 ttattaaccc ccttgaaatt ttatttttaa ccaattttta ttttatacca aaaagaggta
     1201 ttagaaaaca gtaagcccgt tcattatgaa ataaaaacta gtacttttaa tatattgtca
     1261 atgcatatag taaatttaaa agtatagacg cccatattaa tctgaaggta aaagtttatg
     1321 aaaatatcta gggtaatcta tcacacttct tatgttattt tggtttatta attttttagg
     1381 tttaaacata tattaacaaa tataaataac aaatgagttt cataattatt aagaatttat
     1441 aacaaatatt tattttaatg tagtttaata taaacaggta gtttaatgta ggtatgtata
     1501 aagcatttaa taaggcttat aggttttaat gatgatatct ttatatattt taagagatga
     1561 tgaaattaga tatgggtaat agttgtatga gaaaaagtag tatagcacaa aaagtgctat
     1621 atcacaaaat ctcaaataat ttccttttta taacttaaat taaagaataa atatttctta
     1681 taaattaggt gtatgaagta tagcaggaac atctttatta tttaataact tatcaaatga
     1741 tttatggtca gacttatagc caataccttc tctatattct aattcatcaa caattttgta
     1801 ttgttgacag gcatttttaa ccttttcata gtcctcagta gaatgagctt tataaactat
     1861 cttattatta aaagttattt tatcagcaaa tttaggtttt acaaaatatt tagcatcttt
     1921 tattttacca gcattatata aattttggat aacagaacca ttttttaaat gttgtaaatg
     1981 gtcatctaat ttataagtat gtgctatatg agttacattt ttaaattttt cttcaaatgt
     2041 aagagcaatt ttttccatgt aattgaagtc agtattacca tttgtatttg tttctggtaa
     2101 taatattata ttttccctta ttacaccaag gctattaaga gaagctaaaa attctctatt
     2161 tctatattct gatttttgta tatttgttag gttttcatat tttttatatt tatcaaagac
     2221 ggatatacca catccagtag atactaaaac cacaaataca tgattttttc ctctttcttt
     2281 tatagcatta acaatagcac tcccagccca caacacttca tcatcttgat gctgaacata
     2341 gaagacaaca taatctttaa attttttatg actataattc acatagctac taaaagcggt
     2401 taaaatcaaa cataaaacta gaataataga tagaatttta tatttattta tagtaaattt
     2461 tttattctta aatgtcattt aatcatctcc tgaaaggttg tcttagttat attatcaaac
     2521 aaagtactaa aaattatttc ttaaatgctg aaaaatatag agtagattaa tggaataaaa
     2581 tttttttatt agtttaaaat aaagaaaaca tttatgtata agactaatca aaatattaat
     2641 gattgatagg aattgagatt taaagggatt gtacatttat tcgggattca ttttaataga
     2701 attttacttt agtacttaga ataaaagtaa taacttttta aatttaaaga gtacacatat
     2761 atatttgtgt actccttgat gatatgattg cttatttact acaaaaacag agtcttttta
     2821 aacctaaaat atttgatgca ccagctatcg tagttccata atagtaaact ggtttgttaa
     2881 gtgatagaaa atttataatt gagttattac ataatgtact tcctgtgcaa atcactaaat
     2941 cagcccaaga tattacatct tcataatctc gtataccatc ttcaatctta acattatatt
     3001 gaatagtatc cacaaattca ggatttaaat ctaatactct tgtttcgaaa aagtccttaa
     3061 tattatcaat tatggctggt tgatatccta taattgctac ttttggatta ccaaattcca
     3121 tttttataaa ctcagggaat ttttttgcac atacctctgg ctcgttattt ttacaatgaa
     3181 tggttctatc cgtcttgcct aagtatttca taactgcatt taatgatgct ataaaaagac
     3241 ttctatcatg agaattgtca tgtaaatcta atgataatat gtcttttaaa gaaccttcaa
     3301 atgtagatgg agtagaagta aatgcttgtc ctttagctcc tttaaagtca gcttcaagca
     3361 ttatttcttt accaactata attgggaaat ctttacgctt agtatttcca attgcttctt
     3421 ttgaagatag agatttggac acaatactta tcatatccat atttaaatta tatttatcga
     3481 cttgtactaa tagataatct ctcaaaatat caaatatatt catagaaaaa agattctcct
     3541 ttatttttta tttcttcatt taaatcaaaa atatgattta tttttccatt gttcattatt
     3601 cctatcttat gagcaaaaaa cattgcttca gaaatatcat gagtaacatg aatcactgtt
     3661 ggtttgtatt ttatgtagac atccttcaaa attttgctta tatgtttttt tgtaatataa
     3721 tccaatgaac tcataggttc atctaaaagt aatatatcag gttcagctat taaggcacgt
     3781 gcaaaagcaa ctcgttgctt ttcgcctcca cttaaatttt taggatacct attttttata
     3841 tcttctatct gcattaattt agacaagtgg ttagccttaa gaatctgttc atctataggt
     3901 atttttctca atttaagtgg aaaccttata ttatcttcaa cattcatatt tggaaataat
     3961 tcaaaatttt gatatacaaa tcctatattt ctattttctg gaggtaagtt tgatattaaa
     4021 ttttctttgt atgatacatt tcctttagca gatggatatc ttcctgctaa tgtttctaga
     4081 aatagagttt tacctgaccc actagctcct aataaaacaa agtattcatg attattaata
     4141 tttaaactat tttcttgtaa tttaaaatta ggtaaatcaa gagataaatt ttttattttt
     4201 aacatattaa ttcttatcaa cctctctatt aaaaaatatc tcaaaaagca tcaagcatgt
     4261 aagtgagaga aatatcaaaa ttacagctat tccgatagca atgtctatat caccagtaga
     4321 catatttaaa tatatagatg taggaataat ttcagttttc atacgtgtag aacctgctat
     4381 catagctact gcaccaaatt caccaagtgc tcttgaccaa gtcattacag ttgcagatat
     4441 gattccagtt tttagatttg gaagaattat aaatctaaat gcttcccaac tattacatcc
     4501 aagggtacgt gcaacaaata tcatcttttc attactttca tttaatgaag tgtgaagtat
     4561 tttaatagta agtggaagat ttacaaatat ttgtgctaaa actatacctt gctttgtaaa
     4621 tataaaatca agcttaaaaa tcttataaat ggaatctcca atccccattc ttccaaacaa
     4681 aagtaaaaga gcaattcctg atactaagtg tggaagagac atagggagat ttattatctg
     4741 tataatcagt tttttaaatg gtaatttagt aatatgtaaa aaatatgcta ctggaatagc
     4801 taataaaagg catactatag tagatattaa agatgtttta atactaagtg ttattgcata
     4861 ctgtacttcc actgatttta agcatatagg aacataactt atccctttaa tgattaacat
     4921 aagaagtggt gatacaataa acaaaaagac tatagcaaaa aatccagtaa gtagagtagt
     4981 aaaaaattta tttttcaagt ttaatcacta cttaacaggt tcaaaaccat attttttaaa
     5041 tatctgttta gcttcgtctg actctatata atttataaat ttattagcta aatctttttt
     5101 atcactatag tttacgattc ctgctgatat gagttggtct atatttttat cttgggcaat
     5161 ttctataact tctacatctt cattaccaaa gaccgaatct tttgtggcta ttgtagcatc
     5221 agctttactt gatgttaact gtacaatcat ttcatttaca gttgcagctg tagagacaac
     5281 attatcattt atagatttta aattattttt ttcaagtatt ttttgtgtag tcttacctat
     5341 agcattagac tctttgtctc ccaaaataag tttaactcca tctttattta agtcttccaa
     5401 tttttgaata ttagctggat ttcctttagg tacaactatt gcaggtgtat gatgtgcaac
     5461 cgttttatgt tcacctacaa gttctttttc aaaggccttt gaataaattg gttcagaacc
     5521 aacaataaat acgtctcctt tgtgacttgt ctcaatttga gctattagct gtgcagaacc
     5581 tgcatagcta tattcaactt tgacattatt ttctttctca aatttttttg ctatttcatc
     5641 cattggtttc tttaaacctg cccctgaata gacaaaaaga gtctcttttt cttttgaatc
     5701 atcagctgtt gtcactttag tattagattc atcattagct ttgttttctt tagaattaca
     5761 tgcagtaata cttaatgaaa taatcatagc taaagctagt actgaaagtt ttttaaacat
     5821 aagatattcc cccttattaa attagtgtaa attctttttt agtatatcat actaagaaaa
     5881 cgatgtctaa gtttttgtta tgttttataa tgttttgtta tgttttgtta tgtatagtta
     5941 agaaaaaatc tattcataat gtcatttcca taggtagtta ttttattttt aatttttatt
     6001 aatactttaa agtattttaa atttaaaaac ttaaatcaaa ttaacttatt gtagattttt
     6061 tactttttaa ctaattttat atttattata tttcagtgaa aaaatagaac attgaaacat
     6121 atagatatgt tttaattgct ttttattaac aaattactaa aagtattata tcagaattga
     6181 atacaaaaga aagagtatgt atttatgaga tagttgaaaa ttttgatgtg ccacaactaa
     6241 aattattata ttactatata ttctaattaa aagagtactt gtaggtttaa gtacatactt
     6301 tataaatata tttttgtcag atttatttta taaaaagtat ttagactaag tattattttt
     6361 aagtattttt ttgttgaagt tattttttcc ttttttacaa aatgcgtaaa taaaaaaaag
     6421 actcttaaaa gagtctttcc gaaaaatcta tatattataa tatagttata ttttctgctt
     6481 gaggacctct agcgccttta actatatcaa agcttacttt ttgaccttct tctaatgatt
     6541 taaatcctga agtttgtata gctgagaaat gagcaaatac gtcatctcca ctttccattg
     6601 atataaatcc aaatcctttt tcattattaa accattttac tattccatta ttcattaaaa
     6661 atactcctat taacctatat caagatatac ttgatttact tgtgtattac cacaaatact
     6721 attgtatcat agattaacat aaatgtctat ttaattataa tttttagtta acatttttat
     6781 ttattcttaa tatgaaaata aatttaaaca ttttatatta ccaatatatt aatgtaaatg
     6841 tagataaaac taaaaagggt tttctagaaa aaaatctgtc taattatact tacttaccaa
     6901 taccatcact tgatgcaagc aagattccac aactttttct ccgtactcta atataaaatc
     6961 atctaactgt gtatctataa aatcacaata atcatatgaa ctaccaatat aagcagttaa
     7021 catatgtgta catttatcca ttttatctct aaacataatg tatttatccc cctaaaaaac
     7081 tttcatgaaa aacaaaaaga aaatatcttt ttggcaactg gctgacataa cttattttat
     7141 aagcgttagt ccctatagct ttgcgtcact aaatttctct agttttgccg atttagtttt
     7201 attctacaga ttaataatac aatagaatta gttattattc aacatatcta gctgaaaaat
     7261 taataaattt atatatgaac gttaaattat ctgaaaaaat aaaaagcccc tctgtcagga
     7321 gtgacttaaa aattgaattt aagtttgtat ttaaaacaca tttttaataa tgcaaaaact
     7381 aatcaaaaat aaacaattca tcaataggtg tatctactat ttttgatata tctattgcta
     7441 atttcaaaga aggattatac tttcctgctt ctaaacgcat aatggtttct cttctaactc
     7501 ctactttttc tgctaattgt tcttgagtta attcttttaa ttgtctatat ttttttaggt
     7561 tacaagtgaa tttaggcata ttatttttcc tctaaaatat aaagttttat agcataaaca
     7621 tttaaagtga ttgcatatgt aattgatagt aaaacacaca ttaattctat attcctagac
     7681 actatagtaa tacaccataa aatgaataat tctataatag caagctgtcc tgtaaatgcc
     7741 atagctgctt tttcatcttg tacatacctt tcatctgctt tatcaccatt tatttttgct
     7801 ataataaagt ttgagaaaaa agcaaaaaat ccaatatatg taaggtcagc aacattgcca
     7861 gatgaaaaat atctaagact taaaaatcca aggaaaccac aaaaacccat aaaaaatttt
     7921 ttctgaatca ttttttatcc tccttagtaa ttttaaaaga gatatattta tatctttatg
     7981 atacaaatat atctctttta tattcttttg tcaatagaaa atcagtatta tacaatattt
     8041 gtactgcacc ataattgtta gagcaaaaat ctactgcttg agatgtttat gtatgactaa
     8101 atatgatttt aatttcaaat taaaagtagc taaattttat ttgaatagag aaggaagaga
     8161 tattttaata gtaaaacaat atggagttta taaccattct caagttgaaa gatgggttaa
     8221 tatattagga gagtgtgcac taaaaataaa aaaaattttc tatactatat ggttcaagtt
     8281 agatgttata aactatatga tgataactaa atatagtgta caataaatcg ctaagtattt
     8341 tggaataaac aatagcacag ttatagcaac atgaaaataa aaatttttac atagtggtgt
     8401 tgatgccttt tctaaaatga aaggaagacc ataatgaata aaaacaaaaa cactaaagaa
     8461 aaaataaatt aacaagagaa caagaattag aatatgaaaa taaattttta aaagatgagc
     8521 ttgagttttt aaaaaagatg tgtgcctcag ggaagccaca ttaaaaaaca gtggtatcat
     8581 tattaatcaa aagaaagtta gatgtattat caaaaaatta gaacttaaat gcatagcatt
     8641 ttttcataaa tcacataaat ataactccta taaatgtata attggaaaag taaaaaataa
     8701 taaaacaaat agaagattta aaatatcaat agcatatcag aaaataacaa atgatatgct
     8761 agaatttata aaatatatct aatgataaaa atggaaaatc aattataaaa aaggcatatc
     8821 ccgattcatt ttttgttata tagtcaaata agaatactat agatgaaaga tacgattttg
     8881 catatgtatt aagtaagtat tctgatgttt ttggttgata cacatgcaat aaagaagttg
     8941 tgtttgcaga taaattagca aaactatagt ataagttgca acaataaaga aaatgaaaat
     9001 tatcatacta aagcataagg catgttacaa ttttattaga taggacatta acatacatta
     9061 aagtactttt tattataaag agtacttatt tttttgaaat tcattaatgt ataaactatc
     9121 aagaatatta ctcaacataa tttaaaaaca acttgaatag gtatttttaa attatgtgat
     9181 ataataaaaa atagaagtgt atgccaatac acttctgtaa ttataactaa gcattctatt
     9241 cttgaggagt gcttttttca tttctccaaa caagattgtt tatttcatca gcaattatta
     9301 aataaaattt attgtattta agtattcgat ttatcattta aaaattttat tacaatatct
     9361 attttgtttt gctcgttcat tatgtctatt gaacttccat aatcactttt taatttatct
     9421 agaccacttt tgcttatttc tccttctgga agtatactta attctagata tttttcatga
     9481 ccaggagatg acattaatag atatgaacca ttataaggca tacctaaatt ttctatttta
     9541 tctgctaatg ggtcatcttt aaagccacca tttattatta tttttccatc tttctttacc
     9601 catgatatca ttcctccatc agtatatttt gattcatctg catagtagct aagagacgca
     9661 ctttttattg cacttatatc agcttcaagt ttagctatct ttgctttttc tatattttta
     9721 aataatgctg gaagtgctac tattgccaat attcctatta tagcaattac tactaataat
     9781 tccactagag taaatccttt tttatttttc atttatttcc cctccatata aaattaataa
     9841 tatataaatt tttattttgt tgatttctac tttctatatt ttaccatata tagacaaaaa
     9901 aatcactttc tatgacaaat atactattat tttacaattt atggaaatga tttaaaatga
     9961 catttcttgt tagaaaagat ataagaaatg gattaaaata aagaaaacta cagtcatatc
    10021 aatgtcaata atattattta aaagcagatg aaaataaaaa gaggactcag aaaataatgt
    10081 ctatttaatt atacttactt accaatacca taacttgata taaacaagat tatactacat
    10141 tttttttatg ctctagtata aaatcatcta actgtgtatc tataaaatca aaataattat
    10201 atgaactatc agtataataa gtcaaaatat gtatacatga atacatattt taaaagatat
    10261 atattattac atacctaaaa aactttcata aaaacaaaaa taaaatatgc ttttagtaac
    10321 ttgttaacat aacttataat ttattttata ggcattagcc tatatagctt tgtgctacta
    10381 aatttctttg attctagcga tttagtgcta ttctacaact aaaataatac aatagagcta
    10441 tttattgttt ggtagcattg tttgcaaatt aaacaaattt atatatatga atattatttt
    10501 acgtttaaaa aaacagacta aatatgtaga atatttggta aaacttacct ctagtttttg
    10561 tcttaaaaag ctcctattat taatttaagt tagaagaatt aaggaagtga cataaattga
    10621 aagaagaaat attaatagaa aaattattaa gagtagaatt aatagtaatg gagtatttat
    10681 ggaaaaaaga cactctaatg cctaaaaaaa aaattgtaaa agaaataaaa cagatttatg
    10741 gatggcataa aagtacaata aaaatactac taaaaaggct agttgataaa aggtatttgg
    10801 ctagatatat tataaatttt caatcttatt ataaaataat aatagataat aaagaatatt
    10861 atacttttaa gaaaaaggta ctaaaatcta gtaaaagcat aaaaataatg cattcactta
    10921 ccactataca taaaaatgta agtaaagaga agttagacct attagatgag tattatagaa
    10981 acttaaaaga atgatatagt aaaaatcgaa tgtaattatt taccttaatt cctttgtttg
    11041 taaaacttta ttgatataga atttgacata tacataaatt ggtaaaggga tgtatactat
    11101 gaaaattagt aaattaccag aagcggaatt aaaagttatg agatatattt gggaatcaga
    11161 aaaggtatta atatcaagag aaatcaccaa gtctatggaa caaaaatatg aatggaaaga
    11221 tacaactata tttacagtat taaaaagatt aataaagaag agagttttta gaaacggaga
    11281 aaatagataa gtgtacacac tataatgtat tagtaaaaga aaaataatat cagagatttt
    11341 aaacaaaaga atttttaaag aatacacata aaaattcaat attaagttta atgtcagcgc
    11401 tatgtagtaa ggatgatgaa gtagatggtg atattttaaa tttattagaa gaatatttta
    11461 agaatttgaa ataagaaaat gacaaattga tacataataa ataaaaagaa ggtatgaaat
    11521 tataactttt tctaccttca ttttgtttat tattctgaac atgttaagaa aatgaaatag
    11581 gtttgtctaa tatttatata aattttagta gaatatgtat agtatatagt agatagtatg
    11641 tataaaaata aaaactgttc aataagaatt aatatacatt aattcagctg aatccaatca
    11701 aaatacttaa ataaaagtaa tctgaaaata acataattca aatcaattta ttcaaataaa
    11761 cctcaattta tctaa
//
LOCUS       DAEPXW010000110        11657 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.113, whole genome shotgun sequence.
ACCESSION   DAEPXW010000110 DAEPXW010000000
VERSION     DAEPXW010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11657
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.113"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            326..1504
                     /locus_tag="KRM55_003097"
     CDS             326..1504
                     /locus_tag="KRM55_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1595307.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFRNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYRLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            1854..2735
                     /locus_tag="KRM55_003098"
     CDS             1854..2735
                     /locus_tag="KRM55_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1595308.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            2944..3093
                     /locus_tag="KRM55_003099"
     CDS             2944..3093
                     /locus_tag="KRM55_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008819224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1595309.1"
                     /translation="MTTVAEGIETSFQKDFLQEIDCDMLQGYVFSRPLPIKDFEKLMF
                     QNSSN"
     gene            complement(3353..5920)
                     /locus_tag="KRM55_003100"
     CDS             complement(3353..5920)
                     /locus_tag="KRM55_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH1595310.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQSFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     APQKKKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(5923..6528)
                     /locus_tag="KRM55_003101"
     CDS             complement(5923..6528)
                     /locus_tag="KRM55_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595311.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPSDSLEKMLDETMNIFLHGIMNDGGE"
     gene            complement(6886..8346)
                     /locus_tag="KRM55_003102"
     CDS             complement(6886..8346)
                     /locus_tag="KRM55_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH1595312.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            8685..9263
                     /locus_tag="KRM55_003103"
     CDS             8685..9263
                     /locus_tag="KRM55_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595313.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYLPNNHDYISLINKLPQDMFSQLEYNNIQSFYDLIDKYNLKFKIEKEKAFGICVA
                     LLSGLLVKENIEYNHIEVFDFMVDNLVEHILE"
     gene            9556..10806
                     /locus_tag="KRM55_003104"
     CDS             9556..10806
                     /locus_tag="KRM55_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1595314.1"
                     /translation="MLKSLNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLTSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKYLKVTNLHIPFIICALIFVPMAVSVYPFILNIGFPVPFLIFIVSSMLIFF
                     TTSLTSIYVITITQLKTPNELLGKVMSILFSGTSIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            10967..11536
                     /locus_tag="KRM55_003105"
     CDS             10967..11536
                     /locus_tag="KRM55_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH1595315.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPK
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         4028 a         1915 c         1634 g         4080 t
ORIGIN      
        1 tacacataat tatcatacat gctatatgta attactatac ttatacacat aactatcata
       61 catgctatat gtaattacta tacttataca cataactatt atactttcca tacataatta
      121 ctatatttgg acacatagtt atcatacata ctgtatatta agatataata ctttttaaat
      181 tttatataac acagacacat gcaataaaaa agaaggtatc cataataagc tctttgcatg
      241 tacctaaata aaaactgtaa aatagaatat ataaaatcta atctatttta agtaaataca
      301 atttcacttt aaaagaggat gtactatgaa ataccatata tttttaatca taactactat
      361 attaataatc gaactatgta acatttacat atgcaaaata gcatctttta gaaacaaaaa
      421 tataactata cataagaatt acaaatatat ttttttaata aaaccattaa ccttcttgat
      481 aataatattc acaaaattac cattaccact atattatata ttgttttaca tagtaagtca
      541 taaattgctc ttaagcagaa aaagttctac taacaaccat tttattccca atatggcagt
      601 aataagtttt tgtattttac accttattac tgtaagtaca atatcacttg ttaaaaatac
      661 aagtccagat ataatatttg caaatatgac ctataggtta attagtattt taatagcttc
      721 tattttagat tttatcttat ggtactctat gaataaaata aaagagcata tttatataat
      781 aactcaaaat caaatagagt tcagtctatt tttaaaattt atctggttca ctttaggata
      841 tatattattt gatagtatac aaattacatt tgctccacca agttctctaa cttcctactt
      901 tatattggga agtaacatat tattaatctt acaactaatt atattcatca atcatatata
      961 ttccattgaa aaaaatattt atttagaaaa agaacataat agactaaaaa tgataaaaca
     1021 agaacaatta ctaaaagtaa atttattaaa gaaaaaagcc aacattgatg aattaacatc
     1081 agcatataat cgaaaatttg cttttgaaaa aatacagcat tacattgata acaatttatt
     1141 attttcattg atatatatcg atttggataa attaaagacg ataaatgata catatggaca
     1201 tttagctggg gataactata ttattaactt ctcaagtata gttattgaaa acttaggaat
     1261 agatgacata tttgctagaa taggaggaga tgagtttata gttattatgc ctaaatctaa
     1321 tgaaaacacc acaaaagaat ttatagagaa aataagtaaa attatggata atacgatatc
     1381 ttttagctat ggtattgtag aagtttctag cgaaaacaaa atgactgtag aagaaattat
     1441 taatattgct gatattagaa tgtacactaa taaacaaaat aatcataaaa ggaacaataa
     1501 ctaaaatgaa tatttacatg agcttacttg tagtctcact atgtttttta tcttattatc
     1561 tctatcatta taattttttt aaatatctgg acataatgat taataactct aaaaataaat
     1621 acacagtata tattatatat tctatattta attatttaat ttttattatt tgtacttatt
     1681 taaagtttca tctaattata aattggacaa tttttatgtt gattttattc atacaaatta
     1741 aagtaactta taaaatctcc acaataaaaa acatttttta ttcactaaac tgctccatca
     1801 ttggtttagc aataaatata ttttttaggt ctttaatgtc aatagtgtta aatatgccag
     1861 catatttatt tgatagtaat tctattgcaa atatttacag agtatttcct atatcattta
     1921 gctttatagt tacaggacta tatttcagtt ataaaaataa taaaaataat aagattaact
     1981 ttgaggcagt tttagaggac aaaaaaaact taattttctt attgagcctt atgtttggaa
     2041 tgtacttgta tctatgtttg agtttgtcaa tatactatac tgttggaaat gtattgattt
     2101 taaaattata tggaatcaag tctgccataa tagttttggt aggtaactat attgcagaaa
     2161 gatatagctt tagaattact caaataaaag gttatgatat taaaaatcaa atagaatatg
     2221 tagaaagtgt aaagacagag tatgaaatta ataaattgaa tgatattgta tatacagatt
     2281 tactgacagg cttctacaat agaccttttg taaatcaaaa actatcagag tggacatcaa
     2341 atcactacaa atttacctta tgttttactg atttaaatag cttaaaacct gtaaatgata
     2401 aatttggaca ccaatttggt gataaataca tatccactac tgctcaaata ataaaaaaac
     2461 ttataaatgt agaaaattcc ttactattta gatatggtgg agatgaattt ttattccttt
     2521 tacagaatac aagttgtgta gaagcagaaa aaataatgat taatataaat tatgaattat
     2581 caaaattaag taatactgac gagtatcctt atgctctttc cataagctat ggattagttg
     2641 agtgggatgg aatatccgat attgaaactt taatatcaaa ggcagattct ttgatgtatg
     2701 aaaataagct taaaaataaa tctactttaa actagctagt taagatattc tacaaaatat
     2761 atgttataag agagtactaa gaatgtcaaa atatatagat tttgcaaata ttgaatacag
     2821 tttactaatg aatgcactgg atgtaagtgt tagtaaacac ctattagatg aacactttac
     2881 tgttgtttgg gctaatgacc gttattatga aatgttcggc tatacctagc taaaaagtta
     2941 aaaatgacca ctgtagccga gggaatagag actagttttc aaaaagattt cttgcaagaa
     3001 atagactgtg atatgttaca aggatacgtg ttctctagac ctttaccaat aaaagacttt
     3061 gaaaaactta tgtttcaaaa ctcctccaat taacaatata aaattgctta ttataagtga
     3121 tattattgta tcaacaaata aaggaattgt ctcaaaattg attttttcta atcaaatttt
     3181 tattttgaga cattctcatt tttttgcata agaaaatacc caccaagcta cggtttttct
     3241 taccgctgtt cggtaggtat tagtagtatt atgaaatctg aaaactttaa gtattactac
     3301 ttccgctagc gcaatcacaa aggtcgaaag cttcaaagcg aaaataggct ttttactcat
     3361 caaacgtcac cgtacctgcc aacccgtcca ccgttatcat ttgtccgctc ttaatagttc
     3421 gtgtggcaat gtgtgtagcc ataacggctg ggatgccata ttcacgtgcg acaatgcttg
     3481 aatggctaag aggaccacca atgtccgtta caatcgcact tgcagatgaa aataatggtg
     3541 tccatgctgg agttgtggta actgcaacca aaacacttcc aggttgaaag ctttcaaaat
     3601 ctgctggact attcagtaca caagctggag ccgtcacaac accagtactg gtaccaatgc
     3661 ccgtcaacac aattttccca tctttcttct tctgtggtgc ttgtgatata gtttttttgt
     3721 ttttttctgg caacttggat ggtgacacat aacccatgta ttttttaagt tcagcttttc
     3781 gaacaggtat tatcccgttc atatcagata gagacttgtt tttatccaac tgctctataa
     3841 gtacctccaa ttccgatttt gtgagccaat aaatatcatc taaatgtgaa atagctcctc
     3901 ctcgtatgaa tcgttctgag atttcctgaa acatacaacg aatcagagga tgtcccattc
     3961 ccatcaaata aatagcattt tcacgcatag gagaggtttc ctgtgcccaa tggagcaact
     4021 taaaaaatag ttttttacgc aatccaccta tgtgttgtaa aatctcttct tctgcatgtt
     4081 ttctacgctt ttcaaacgtg gtctggcgta aaaaaggact ttcccctttt ccttccacaa
     4141 atgtttttac ggattcaaaa gttggtgtaa gtgtttcctg cggtgtggaa tgcgcaaaat
     4201 caaactcata agcggtacga ccaaactctt taaagtactt attgattcga tttttccatt
     4261 ctatccatac ttcctgtgaa actccaacag gcacaactga agacatgaaa tcttctgcta
     4321 tctttattgc aggactgttt tgcagataaa ggttgatgct gttattttgc tttacccatt
     4381 ctgaaatacc ccacaactcc ttttccgatt gcagaacaat cgtatcaaac ccaagcagga
     4441 aaacggaagt atccgttata ccagcacgtc gaactgctcc ttgaaataat tttgtaaata
     4501 atgtttcact gatagaagca gcaggcaatg taagctgaat ccttgtgaaa taaatacatg
     4561 cggcataaaa tattgtctga ataccctcca taatttgatg ggcgttcata gtatgcaggg
     4621 gcttttcttc ccattgttta atagcatcct catatccttt tcgtgccgtt tcccagcgtg
     4681 caacgctgtt cataagtgtc ctacgtaaag agcgtgggga aagggatttg atagcaatca
     4741 aaagtggctt tgatttagca gaaagataaa catatccatt aataaccgta tatgccccgt
     4801 tttttggtaa taattttttc gcacttttac caaacatatc tatccataaa agctctgatg
     4861 cacggtttac gatttcaaga ccaagcgtgg cgaacaaagg tgtaacagga tttggcaagt
     4921 gttctgccaa actccccttt gtgtatacaa catcctgttc tggcaatacc cattctggtg
     4981 gcagaacagt aattggacga gcctgaacaa tgtataattt atctttttcc agtgcccact
     5041 ctacatccat aggcatttga taatacttct caattttctt tccaagctgt atcagttgca
     5101 ttacctgatt acgagtaaga gcatattttt ttctcaacct ttcaggaacc atggtttctt
     5161 ctgttccttc tgaagtacga accgtcataa tctctttatt tgccacttca tacgatataa
     5221 ttcgttcgga gtccttatcc actacgattg tatcgggtgt aactaagcta gaaaccaccg
     5281 cttcaccaag cccccatgca gcgttaataa tcatttcgct acgtctacca ttgattgggt
     5341 ttaacgtaaa cataatacca gatgaatcgg aaaatgcaag cttttgtact acaacagcaa
     5401 gtgcgacaat ctcgtgcttt atattattct tcacacgata agcaatagca cgagctgtcc
     5461 ataaggaagc ccagcatctc tttacagcgt caataacttt atcttcacct tgtatgttaa
     5521 gataagtttc ctgctgacct gcaaaagaag cgtcaggtaa atcttcagca gtcgcagacg
     5581 aacggacagc caccgatatg ttccctaatc cagcataagc cattttaatt gcgtccgaca
     5641 cttcctgtgg catttctcca ttatggaaaa gctcccctat tttcttagat acatcttcaa
     5701 gttggctagt attattggaa tcaataccat ctagcagttt attaattcga gactgaatat
     5761 ggttcgtctc aacaaaactc tggtatgaag cagtcgtaac atgaaaaccg tctggcacag
     5821 ggatacctgc tgtcaatagt tttgataaag acatcccttt tccaccaaca atttcaatgg
     5881 ttgcttgttt atgttccagt ggcaagacat aataaatcat aatcattcac ctccatcatt
     5941 cataattccg tgcagaaata tattcattgt ttcatccaac attttttcca aactatccga
     6001 tggtcgtgac gtgtagctga ttgataacat ggagttaatt aacaaacgtg tcacaagagc
     6061 cgtatccgtt ttgcgaaaga tgcctgtggt cacaccatta tcaattaccg attttataat
     6121 atcttgatat gcataacgag catctttaag tctctttcga tactcttctt ctaaataatc
     6181 agattctgta tttaaccaca tcagtacagt tctatactgc tctggaaatc taagatgatt
     6241 aagcatgatt tttctaaggc actgttgtgg tgaaggttca ccatcaataa tcctatgaac
     6301 ttgttggata gttttttcta tttctttctc aactgcatat acaacaatct cgtctttcgt
     6361 tttaaaaaaa tcgtatagac ttgactttcc catgttggct aaaactgcaa tttctctcat
     6421 tgatgttttt tggaatccat tttcagccat gagactcaaa gcaacagcaa ctattttttc
     6481 tcggcgttct gcttgttgtt cgggtgtaag cacaattcct tttggcatag ggcgatacct
     6541 ccttttagcg accactggtc gtttcttttt tatttatcat acagcgacca acggtcactt
     6601 gtcaaggtta atttttttca ttgtatatgg tactcgagat aaaaatgttc attttagaat
     6661 ttgctctatt taagtagaaa taggcttcat cattagaaaa caagactata aatttgagat
     6721 atttatcatg ttcaaatttc atcaatatca aagtttaaga tattaataaa aaaagaatta
     6781 ctaagaaata acatataaag attcaaaaaa ggagttgaac ttaaaattca attacaaaaa
     6841 atcaaattta agacaactcc tttattcttt atctctattt atttattaca actccctaac
     6901 atttaccact actgccttag gtctagtcat agcctcgatt gaatacttaa caccttgagt
     6961 tcccatacca gatgccttta cacctaaaaa tgggaagtgg tctggacctc tttcagtctt
     7021 attatttatt tgaacagtac caacttcaag tttatcagct atataaaatg ccttatcaat
     7081 atcacttgta aatactgatg attgaagccc atactctgat tgattagcaa tttcaattgc
     7141 ttgatttata tctttaactc ttataattgg aagtactgga ccaaatggtt cttcccaagc
     7201 aattttcata tcaacattta cattatctaa caatgttgga tagaataaat tattttttct
     7261 aacattgcct gttattaact ttgctccttt atgtaatgca tcatcaacca acccttgaac
     7321 aaaatcagtt gctttattat ctataagagg agtgataact acttcatcca ttggatttcc
     7381 aattgtcaac ttctctacca atggctttat ttttccgacc aatttatccg ccacactctc
     7441 ttgtactaaa attctcttta ctgccgtaca tctttgtcct gaatatgaat acgctccaga
     7501 tactatattc ttagctgcaa aatctaagtc tgcatcttct aatactatag ccgcatcttt
     7561 tccaccaagc tccaataata atggtaccat tccagatatt ttagatatat gctgaccaac
     7621 ttcagtacta ccagtaaagt taataaaatt aattccttta tgcgttacaa cataatctcc
     7681 tatctcacta cccctacctg taatagtatt aagtactcca tctggtatcc cagcttttct
     7741 cataatttct accacatgaa gtgcgctaat agccccttgt gtagcaggtt ttaatacgac
     7801 tgcatttcca ccaataagtg ctggagcaat ctttgacatt gataaattta caggataatt
     7861 aaaaggagat atagctaaaa cagtacctaa tggaaccctt gaaacataag acatcttatt
     7921 tcttgttcca ccagggaaat tatctccact aatggcttca ccctccatat tttttcccac
     7981 atcagctgtg tatcttaaaa aatctgctgt tctctcaact tctgcccttg cagattttat
     8041 gtctttggct atttcaagta ccagtatatt agctatctca tctatatttt ctaacaataa
     8101 atcagcagcc ttatgaaata tattggctct cttgtataca ggcatttcag cccatacttt
     8161 tatactctct tttgtgtttt ttataacctc atctacctca tgttttgtca tagattgtac
     8221 tttcccaaca agagaattat ctattggtga gtaaatttct attggctttc tcgaattaga
     8281 ttctacccat tttccattta ttaaattttt atatacattt tcttttgttt taagttcatt
     8341 aaacatattt ttattcctct ctctgatata actttgtgta tttaaattat agccatttat
     8401 tcgttatgta aacatttctt tttttcataa acgtttacct ataaaaaaaa ttttaagtta
     8461 acgtttttct acattcttct attttaataa catactagct ccaaatctat ataggtcaca
     8521 ctttaatatc aatatgccaa tataccaata taccaatata ccaatataaa tattataaac
     8581 ataaatcact tgacaaattt ataagtagac aatattatat atctatgact taaaatattt
     8641 ttaaagtcat agatatcata tatagacaga aaggattgat aaaaatggct aaaagtttta
     8701 cagaaataga aaaagacaat ataagaaaaa gactaatttc agaatgtgaa atcaactggt
     8761 ctaaatatgg atacaaaaaa actaatattg atgaactttg ttcaaaatca ggaattgcaa
     8821 agggttcatt ctacacattc tttgattcaa aagaaaagtt attttttgaa gtattaaatg
     8881 gaatccaaaa cagacttata tcatcagtag atgaaatttt aagtaatatg cctccaaaag
     8941 aaggctttgc aaaatcttta aaaatgttat atcgattata tgataaaaat ccatttttat
     9001 atttaccaaa taatcatgat tacatcagcc taataaataa actacctcaa gatatgtttt
     9061 cacaacttga atataataat atacaaagtt tttatgactt aattgataaa tacaatctca
     9121 agtttaagat agaaaaagaa aaagcctttg gtatttgtgt tgctctacta tcaggtctat
     9181 tggtaaaaga aaatattgaa tataaccata ttgaagtatt tgattttatg gtggataatc
     9241 ttgtagaaca catacttgaa taataattta aaacaatttt tgtaaatatt cctttatata
     9301 gagaaagatt aatatgatta aattaataca aaaaataaat gctataattt acaaaataaa
     9361 tgataaacta aatatccaca caaaacttat agaccctagt aattacctta tgctgcttta
     9421 ctctatgtta tctataatag tttctatatt tctaataata ttatatatta aagtaagaaa
     9481 aaaattcctt acaataatta ctgttatatc aattattgta aattttttaa taatcttaga
     9541 taggtaggta tatatatgtt aaaatctttg aatactttta ataaaaattt caacttgatg
     9601 atattaggtc aaataatctc attatttggt gcatcaatac tcaagtttgc tttgtcttta
     9661 tacatacttg atataactgg taaagcagaa atatttgcta ctatactagc agtatcttca
     9721 atcccaatta tagtattctc ccctattggt ggagctattg cggatatatt caacagaaga
     9781 aacttaatgg ttatttttga tttttcaagt agtcttacag tactaatctt agcagtattc
     9841 ttattcaaca ataatggttc aatattactt gtaggaatta ttatgaccat attatcagtc
     9901 ataagcacaa tgtatcaacc aactgttcag tcaagtacac cccttttagt tgataatgag
     9961 catttaatga atgcaaatgg tattgtagct ggagttgcat cccttacaaa tattgcagga
    10021 cctgtattgg gaggtgtctt gtatggtgtg attggaatta atgcaattat agttataagt
    10081 tgtgtaagtt tctttctatc tgcaattatg gagatattta tacagattcc ttttatcaaa
    10141 caagagcaaa acagcaacat tataaaaact atatttactg atataaagga tggtattgtt
    10201 catatatgta aagaaaatag atttatacta aaaatacttt ttttagctat agcaataaac
    10261 ttatttttaa cttctatgtt aattgtaggt atcccctata tagtaaaaat aactatggga
    10321 gctagtaact tcttatatgg tctagcagaa ggagcaattt cttttagttc actagtagct
    10381 gctgtgagta ttggtatttt ctcaaaatat ctaaaagtca ctaatttgca tattcccttt
    10441 atcatatgtg cacttatatt cgtaccaatg gcagtttcag tatatccatt tatattaaat
    10501 ataggatttc cagttccatt tttaatcttt atagtatcat ctatgctaat attttttaca
    10561 acgagcctta cctcaatata tgttataaca atcacacaat taaaaactcc aaatgaactt
    10621 ttaggaaaag taatgtcaat tcttttttca ggaacatcaa ttgcaatgcc ccttggtcag
    10681 gttatgtatg gtaaactttt tgatttatta tcagatagag tgtacatcat tatactagga
    10741 gttggattta ttacattact tatagcattt gtatcaaaga taacattgag gaacgaaaat
    10801 ctttagatac aaagaattta gatataaaga tttaattttc actaatttct gaatttaaat
    10861 gcaaaattgt gtatcagtat gttgacgttt tagaaattga ttgatataat caatggaaaa
    10921 taaactttat aaaaattcaa aatattcagc tagaggagtg ataaaaatga gttacatgcc
    10981 aactttagaa caagcatggg aaatattaag aaaatacaac aaggaagaat ttcatataag
    11041 acatgctcaa attgtatctg gagttatgag atactatgca aaggagtacg accctaaaag
    11101 agtagaattt tgggaaatag ttggactttt acatgattta gattttgaaa tgtatcctga
    11161 tgaacattgt gttaaacaaa gagaattaat gacagagctt gatttagata aatcaataat
    11221 cgattctaca ataagtcatg gatatggatt aactggttca gatgttaaac cagagcaatt
    11281 tatggagaaa gtattatttg ctgtggatga acttactggt ttaattggtg ctgctgcaat
    11341 aatgcgtcct tcaaagagcg tttctgattt agaattaaaa tctgttaaga agaaatttaa
    11401 agataaatca tttgctgctg gctgttctcg agacgttata agaagtggtg cagaaatgct
    11461 tggatgggaa cttgataagc ttatccaaac aactatagaa gctatgagaa gcttgattcc
    11521 agagatggca atatagctcc tccatacata taccatagaa gttacatctt taaagagcat
    11581 ttctcttttt gatgcaactt ctttttatat tttgtagaat aaaaagttta atattttaaa
    11641 ctcactatat aatctat
//
LOCUS       DAEPXW010000111        11603 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.114, whole genome shotgun sequence.
ACCESSION   DAEPXW010000111 DAEPXW010000000
VERSION     DAEPXW010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11603
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.114"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            106..669
                     /locus_tag="KRM55_003106"
     CDS             106..669
                     /locus_tag="KRM55_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595316.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            1066..2766
                     /locus_tag="KRM55_003107"
     CDS             1066..2766
                     /locus_tag="KRM55_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595317.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            2936..3553
                     /locus_tag="KRM55_003108"
     CDS             2936..3553
                     /locus_tag="KRM55_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595318.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            3914..5107
                     /locus_tag="KRM55_003109"
     CDS             3914..5107
                     /locus_tag="KRM55_003109"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH1595319.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEYVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            5125..6417
                     /gene="lysA"
                     /locus_tag="KRM55_003110"
     CDS             5125..6417
                     /gene="lysA"
                     /locus_tag="KRM55_003110"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBH1595320.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            6634..7293
                     /locus_tag="KRM55_003111"
     CDS             6634..7293
                     /locus_tag="KRM55_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1595321.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(7448..8533)
                     /locus_tag="KRM55_003112"
     CDS             complement(7448..8533)
                     /locus_tag="KRM55_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1595322.1"
                     /translation="MIIISRENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            8724..9440
                     /locus_tag="KRM55_003113"
     CDS             8724..9440
                     /locus_tag="KRM55_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH1595323.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            9498..10076
                     /locus_tag="KRM55_003114"
     CDS             9498..10076
                     /locus_tag="KRM55_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1595324.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            10470..11342
                     /locus_tag="KRM55_003115"
     CDS             10470..11342
                     /locus_tag="KRM55_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1595325.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
BASE COUNT         4789 a         1211 c         1985 g         3618 t
ORIGIN      
        1 ccttaaaatc aaaatttgta aaaccacatt tattatgtta gaatatctta tgatattaaa
       61 ttgtaagtgt ataatattat ttagttacta gattgggggg aaatgatgaa taaagtctat
      121 attgtaacaa catatacagg aactatatta tcttacttaa taaggaatat aagtaaaaag
      181 ctgtatacac atgtgtcaat atcattaaat gaaaatctaa aaccaatgta ttcttttgga
      241 aggctaaatc caaggaatcc atttattgga ggatttgttg aagaaaatat aaatcaagga
      301 ttatatgcta taagaaaaaa cactgtgtgt agggtatatt cgttagaagt agataattta
      361 caatatgaaa atctatataa aaatataaaa ttaattagtg attatagaga agattactat
      421 tacgatacaa tggcattaat atatttacta atgaatattc agagacaatc tgaatataaa
      481 tatgtatgtt caaattttgt tgctgacatg ttagaaaaaa gtgagataga cattttaaat
      541 aaacaagcat ttgaagtaac gccaaatgat ttttataatt tatctggctt aaccttagag
      601 tatgaaggtt tattatcaga atataattct agacaacatt cttatgtatc aaaaatcgca
      661 aacatttaaa aacttgattt agagtttttc atataaaaaa atattgctag ataattaggc
      721 tgaagatagt agtttaactt cgataggatt aagaatttgt aaatcttagt tagaatactt
      781 tcttcagttt ttaaatttct gctaatattt gtatttttat aacatttttg gatatatata
      841 atacagaata gtgcaaaaat cccactcctt taggtgcggg atggatagca caaacagtgt
      901 ataaaaagta tttatacata cacgtataat attaaatata gttgaataag cagaactata
      961 aatatataaa gatatcttaa tatataataa atatgataaa tatttatttt ttgtaaatat
     1021 atggatataa tagtaataat aacatttttt agagaggagt attaaatgaa acgatatctt
     1081 aaaacatatg gagttgcatt aataattgta ataatttatg catttattaa attacctgta
     1141 ctaagattag attttacatc tttattttca gtaggaataa ttttctttgt tgtagcagga
     1201 atactagata tgatgttaga tagaaatgaa agagcatcta aaatggctaa atataatttt
     1261 tcaatagcaa tagctttgct tgtgtatatt gtagtagttc cctttataac ttctacacct
     1321 gtacttcatg caaaatcata tagagaacta ttgggaaaag taactgaaag taaatttact
     1381 gatgacatta gccctgtcag tgtaaatgac attcgtcttg tagatgaaga tatggcaatg
     1441 aaattaggtg acaaaaagct tggagaagtt cctgcaatag ggagtgtatc caaattagga
     1501 aaatttcata tacaaaatgt agatggagag ttgtactggg tagcgcctct tgttcacaga
     1561 gacataatta aatggataac atctctaagt ggtacaagtg gttatgtaaa agtatcagct
     1621 agtaatcctc aagacgtcca attagttcaa gaaatagatg gaaagccaat aaagatagtt
     1681 taccaaccag aagcctactt acatcaagat ttacaaagac atttatacat acatggtatt
     1741 gtaaatgttg gtatgacaga tttcactctt gaaataaatg atgaaggaag accttattgg
     1801 gttgtaagtt tatatgaaca taaaattggc tatggaggag caaatgcaac aggaatagcc
     1861 actgttgatg cagaaactgg aaaaataaat gtttatgatg ttaaaaacac acctaaatgg
     1921 gtggatagaa tacaaccaca aagctttgta acagaccaga ttaaagactg gggtgtttat
     1981 gttaatggat ttttaaactc tgttatatca gaaaagggag ttttagtacc aacagaaggt
     2041 acatcattag tttatggcaa tgataacagg tcttattggt atacaggtat aacatcttca
     2101 ggtggagatg aatctacaat tggatttatg ttagttgatt ctagaacaaa agaagctaga
     2161 ttatataaac aaccaggagc tactgaaacg gctgcaatga aatcagctga aggtaatgtt
     2221 caagaaaaaa attatgaagc gacgttccct gtaatgtata atatattggg tcagccaaca
     2281 tatgtatcat cattaaaaga taaggctggt cttgttaaga gagttgcatt tgtatctgtt
     2341 gaagattata atgtacttgg aataggtgaa gataagaatg aagcattaag aaactataag
     2401 gatgcattag aatctaaggg taatgattta aaacttgata atgatttaaa agatgaggta
     2461 ttagaaggca cagtgacaag aataagccca gatgtgcgag gtggtaacac taattattat
     2521 gtaactttag attcaaataa agatataata tttagggcta cttcaaaagt atctagcgaa
     2581 ttgccattga ctcaggttgg tgataaagtc aaaatatcgt attcaaaaga agaatctggt
     2641 gtaatagaaa tgtcagaatt tgataaccta aatattgcaa actttgaaga taaaaaagca
     2701 aaagaaaaaa caggaactga tgaaaataca gattccaaag attctgaaaa tcaaggtaat
     2761 gtataattta aataaaaaga ttgataatag tatttaacat agtgatagct aatttttata
     2821 gaatttaatt ctataaaaat tagctatttt attttaattc tttgtaaatt taatgtcata
     2881 aaattaatat aatattagta caactttgca aataatactt caaggagaat gtactatgac
     2941 gaatatggaa aaagagatat tacttttaat tagcagggtt agatgtgtta cagagtctca
     3001 atttagaaaa atttatggag accaaaaaag atacaataaa aaaaatttta aaaaaacttt
     3061 gagaaaaatg tgtagtgaat atacactaaa aaaatatcct tgtgatgtgg attattataa
     3121 ttataaagac ctctcttatg tatactattt aaacggtagt aaacttttta agggagatga
     3181 tttaataaag gctctagtag gatcagaatt agttgttaga atcaatactg caggttgtga
     3241 tgtaaaaaga ttttaccgaa atgttagtgt agatgatgtg aaatacgatt tatttattga
     3301 atatacagac caatttggta atataaagca agttttagtt gatgttgact taaataatga
     3361 aatagacatt tctaaatacg aaaatctttc taaaaaaata gataaatcta caattccatt
     3421 ttttaaagta ccaaacgttt tggtagttac accagataat ctatccgaat taaatgattt
     3481 agagagatat gataatgagt atagcataaa ttttatagat ttaggattaa ataaactatt
     3541 taattgtata taagctaact ttagaaaaga aaactatcga tttgccacat tttgtaaaat
     3601 aattgttgca atattatata gaatatgata aaactatatt aataaattaa ttaaaaataa
     3661 tgagcctagg gtagaggtag ctgtattcaa tagtattcaa taggagctgg taagcgttga
     3721 taattgatga aagggtatat agccgaagaa attttgttga cggacaaatt ttctggactt
     3781 atgcagaata tgcataaggc tgtcactttt aaagtggtga gctacaaggt tacttggtct
     3841 atgaaattta cacgtccaaa gtataccttt gggcgttttt atttatcaaa atttagcttg
     3901 agggggagaa agcatgagta taattgttca aaaatatggt ggaagttcag tagcagatac
     3961 tgaaaaaata aaatcaatag cagaaaatat aatagaacga agaaaagaaa atccacaaat
     4021 ggtaatagtt gtgtctgcca tgggaaaatc cactgatgaa tatataactt tagcaaagga
     4081 attgagtaat gaacctagta agagggaatt agatgcttta atgtctactg gtgaaatgat
     4141 ttcagcatct ttattatcaa tagcattaaa tgcacttgga tgtaaagcta taagttataa
     4201 tgcttatcag ttaaatataa aaacgagtgg tcttcatgga aagtctcaaa ttgatgatat
     4261 aaacgtaaac agaattaaaa atagtttaga tgaaggaaat gtcgtgatag taactggatt
     4321 tcagggaatc aacgaagatg gtgatgtaac cactcttgga agaggtggtt cagatacatc
     4381 tgctgtagct cttgcggtta aattaaatgg aaaatgtgag atatatacag atgttgatgg
     4441 aatttatttt acagacccaa gaaaatattc aaaggctagt aaacttgatg agattgaata
     4501 tgaagaaatg cttgagttag cgagtttagg agcacaagta atgcattcaa gaagtataga
     4561 gcttgcacaa aaatatggtg ttgaaatcta tgtcggacgt acatgtggta cagaaaaagg
     4621 aacatatata agagggggaa aagacatgaa attagaggat aaagtaataa caggattagc
     4681 tactagtgat gatgacagtt ctataacaat aaaagatttt aaagctgaaa atatatctag
     4741 cttatttgaa gatatagcaa ctataggtat aagtgtagat atgataagcc aaactgcacc
     4801 tattttagat aagataagtg tatcatttac agttccaaaa gaagagttgg gagaatgtaa
     4861 aaagatagta tctaaatata cagatgaaga atatgtagtg attgataata atatcactaa
     4921 attttcttta gtaggtcttg gtatgaaaaa tacttctgga gttgctgcta aagtatttaa
     4981 gatattcaat gaaaatggta taatgataaa acttataact acatcagaga ttcgtataac
     5041 ttgtgctata aattctgatg ataagcaagt agctatagaa aaaatagcag aagtatttaa
     5101 tatataaaat ttggggaggc tattatgaaa cttcatggaa ctatgactgt aaataatgat
     5161 gaattatata ttggaggagt gagttgttta gaacttagta aaaaatatca aactccactt
     5221 tatgtatttg atgaagcttt agttagacaa aattgtagag aatatataga atattttaag
     5281 gctagagagg gaaaaaataa ggttgcttat gcagggaaag cttttttacc tctttacatg
     5341 tgtaatctta taaatgaaga acaaatgtgt ttagatgtag tttcaggagg cgagttatat
     5401 acagcttata aatcaaattt tcctatggaa aaagttttct ttcatggaaa caataagact
     5461 aaagaagaaa taaacatggg attagattta ggtgtaggta aatttgtagt ggataatttt
     5521 tatgaattag atttgcttga agcattatgt gaagataaag gtaaaactca agagatatac
     5581 tttagaataa ctcctggtat agaagctcat acacatgatt atataaaaac tggacagata
     5641 gattctaaat ttggatttgc tttagtaaat ggagatttat ttagagcaat agaaaaatta
     5701 agtgaatata aaaatattaa acttgtaggt cttcacgctc atataggttc acaaatattt
     5761 gatgtagaac catacataga tacagtggat ataatgatga acttggtaaa agaaataaaa
     5821 gaaaaattca acatacaact aacagaaatt gacctaggtg gaggagttgg cgtttattat
     5881 agcgaaggag ataaacctaa aactataaaa gagttttgtg aaaccataat cactaaagca
     5941 gaaacttcat gtaaagagct tggaatagaa gtacctacat tggtaataga accaggaaga
     6001 tcaatagttg caaatgcagg aagtacattg tatacagtag gttctataaa agatataaaa
     6061 gatgttaggg tttatgtaag tgtagatgga ggtatgacag ataatgtaag accttcgttg
     6121 taccaagcta gttatgagtg tagtattgtg aataaaatta atcatgaggc tatgaatcat
     6181 gtaacaatag ctggaaaatg ttgtgagagt ggagatatat taattggaga tataaacata
     6241 atggatatta aaagtggaga tatacttata acaacatcaa ctggtgcata tggatattca
     6301 atgtcttcaa attataataa aataccaaga gcagcagtgg tatcagtatt tgatggaaat
     6361 gataagataa tttgtaagag acaaagctat gaggacttat tagctttaga gatataaaat
     6421 agagaagtat ataataaaaa ttaaatatta aagtttatta tgagcagatt tgctaggata
     6481 tgtatctcta aattaatttt tggtttattg tatcgttcgt agcatatctg cttatttttt
     6541 gttttactaa caaatttctt gtaataaata taaaatattt taaaaacttt ataattatga
     6601 taaaatttaa agtatatgac aaggagggat ttaatgagag gaagagtaat tttattaata
     6661 tcgatattat ctatatttct tgtaggatgt tcatttaata aaaaagatga aataaattta
     6721 gtagagcaag gaaaaacata tttagaaaaa cataactata aaaaagctat ggaatcatta
     6781 tcctctgcac tggaagaaga tagtactaat gagaatgcaa gagctatgta tatgcaagct
     6841 atgagaatgt caaatatgac ggagtttgaa gaattaaaaa attatgaggg tgcaatcaag
     6901 gaacttaaac ttatagagaa aatcaaaaat ggttcctctg ttattaaaga agaggcaact
     6961 aaaaagaaag aagagttaac taaattagaa aaagaacaaa acgaagcaga ggaacaaaga
     7021 aagaaaaagg caaaagatac ggctggagaa gataggtata gagttgaatc agatgcaagg
     7081 aaatcttctt atagtggaag tagtaaaaat aataaatcta gttctaaaaa taatgataaa
     7141 aaatcagata gtaataagtc tgacaataat aacagttctt ctcaaaatca agaaaagcca
     7201 aataatagta atccaacacc agcaccaact ccacaagata ctactggtgg ttcagatagt
     7261 ggtggaaatt ctcaaaactc aaataatcaa taagtataaa atatatgcat aaatttaatg
     7321 aacaaattat atattataaa aaatatctct tagcaatttt ttcttactaa gagatatttt
     7381 ttgagaaata atttaataaa tagcagttaa attttaaact aaaaattaaa gtcacagtag
     7441 agataagcta ttgtaaacga ttatctatat atttatcaac ataagttttt acaacagcag
     7501 ctattggtac tgaaagaaaa actcctatga aaccaaatag agattgtccc accaaaatag
     7561 cagatattac ccatatagct cctataccaa cttgattacc cataactttt ggttctataa
     7621 aatttccatc taattgttgc aatataaata gaaatgcaat aacccatata gttttttgtg
     7681 gactatataa tatagtcatg gctattggag ggattgcacc aataaaagga ccaaaatagg
     7741 gaattatatt acctaagaat attattgaag ctaaaaataa agcattttct attctgataa
     7801 caaattgaaa tcctaaaaat gcaattatac caataataag agagtctaat attctaccaa
     7861 gtaaataatc atagaaaata tcatgagtag tcctaaaaaa ttctataatg ttatctgcct
     7921 tgtttctagc agtagaagaa tatagaaatc tcttaaatcc caatgcaatt ttttctttgt
     7981 catatataat gtatatagat agtataaatc ccattgtcat attaaatagc atagaagata
     8041 tactaagtgt atagattaag aagtttttag gaattttacc aacaaaatta cttgcttctt
     8101 ttaataaatt atctaaacta tgttgtatat gaggaattaa agtttttaga aaatctatgt
     8161 ttgacatatt tttttctata aaactatcta tataatcagt atacataggc atttcattta
     8221 tcaatctatt taatgtatta gctattgatg gaattaataa cctaatggca aaggctaaaa
     8281 taaaacctat aaatatataa gataaaaaaa tggctaaaag tctatgtgct ttgaatttta
     8341 cctcaaaaag catcacaagt ggatttaaaa gtaaagcaag taaaatagct aataaaaatg
     8401 ggctaaaaaa ctttaagaat ccttcaatac tagatataaa gtctgatgga gtattaataa
     8461 atttaaaaaa taaaattcca ataaacacga ctattaaata gtattttata ttttcccttg
     8521 aaataataat cacttcctta aaatagtgtt tagtcagcta ttacatatta atagtatgtg
     8581 aaaagaaatt acaattattt aggaaaatta aataattttt ttgcttgttt ttaattaagg
     8641 tctagtatag tataataatg tagcaaaatt aacattgata agaatattaa acacacataa
     8701 tttaagataa ggaaggatta agtatgagaa ttaataagta tatagcttct tgtggaatag
     8761 catcaagaag aaaagcagaa gaaataattc ttggaggaag aataaaggta aatggaagtg
     8821 tagtaaaaga gttatctttt aatattgatg aagaaaaaga catagtagaa tttgataata
     8881 aaaaagtaaa accaagtgaa aattatatat atatagtatt aaataaacca gagggatata
     8941 taactacagt aaaagaccaa ttcaatagac ccagtgtaat agacatactt aaagatgtaa
     9001 gggaaagagt atatccaata gggagattag attatgaaac tagtggatta ttaatactta
     9061 ctaatgatgg cgatttaaca tataagctta cccatccaaa gcatgaaatt gataaaacgt
     9121 atgtggcaag tgtgaaggga attataagtg atgatgagat aagacaattc gaaacaggac
     9181 taaaaataga agattacaca acagcacctg ccaaaataag ggtaactaaa gaaaataaag
     9241 aaaaaaatta ttcagtgtgt gaaataacta tacatgaggg tagaaataga caagtaagaa
     9301 aaatgtgcaa agctataaat catccagttt taaatttaag aaggatttct gtggggaaaa
     9361 tagtattaaa agacaccaaa gttggagaat atagatacct aacagaagat gaaataaaat
     9421 atttaaaatc aataaaataa gataaaaata aattgagaaa aaatgaaata aagttaatag
     9481 tagggagaaa tagtattatg gcatatgcaa agtatttaac taaaattaca gatataaata
     9541 aattttattt agaaaatatt ataaatgaag gtgacatagt aattgatgct actatgggaa
     9601 atgggtatga tacaaggtat ctagctgaga aggttggaga aaagggcttt gtatatgctt
     9661 ttgatataca agaagaagca ataaagtcta caagaaagaa actagagaaa gaaggatata
     9721 cagatagagt aaaattgata tttgatgggc atgaaaaaat gaatcaatat ataaaagaag
     9781 aagtttcatg tgttttattt aatttgggtt atcttccaag agcgaaacat tcaattataa
     9841 ccaaaccaga tacaacttta aaggctataa agttaagttt agaaatgcta aaagaaaatg
     9901 gagtaataag cattgccata tatacagggc atgatggagg tcaagaagaa aaagattgca
     9961 tatataacct tgtcaataat ttaaatcaag atgaatttaa tgttttagaa tctaagtttt
    10021 taaatcaagt caataaccca ccacaattga ttttaattga aaagaaaaaa gcataataaa
    10081 tactaaaaaa cttgacaaga ttgtattaag agttaatata tatagtgtga cctattaaaa
    10141 atactttaaa taataagtat acaacagctt attctcaaaa caaaatatac atctaaatat
    10201 gcaaaataag atagataact tttaaatgag taaaaattga aaaatttaaa agaaatattg
    10261 gataaatatt aaaaaatgca aggaaagatg gtataataaa tttaatcgaa aatactatgt
    10321 gaagtataag gtacagaaaa gttagaattt tatgagttta agaagctatg ataaaaacta
    10381 agatgaaatt gagataaaaa ataaaatttt tagagaaaaa gacagtgtta ataaaacaaa
    10441 atagtttata taactaaaag gagaaaaaaa tggaagaaac aaatgaaatg aaggacagta
    10501 aacatttgat atcaaatata caatctcaat atacgagatt gagtaagggt caaaaactta
    10561 tagcacaata cattttaaat aattatgata aagttgcatt tatgactgca tgtaaattgg
    10621 gtgaaactgt aggagtaagt gagtctacag ttgtaagatt tgcaaatgca ttaggttata
    10681 gtggatatcc taaattacaa gctgcacttc aagaactcat aaaaaataaa ctaactacag
    10741 tacaaagagt tgaaatggca catgattatt ccgatgattt tgcaatacta aacaaagttt
    10801 taaaaagtga tatagataat ataaggtcta cactagaaga aattgacgag agagcgttta
    10861 aagaagcttc taacaaactt ttaagagcga gaaaaatata tatacttgga atgaggagtt
    10921 cttttgtagt agctcaatat ttaggttttt acttagatat aatacttgac aatgttcata
    10981 taattagaat ggatatggga gatgcttttg agcagattgt aagaataaat gaagaagatg
    11041 taatagttgc tattagtttc cctcgttatt ctaagaaatc ttatcaaatt gtcaattatg
    11101 ctaaggaaaa aggagcccat gtaatatcat taacagatag cttatttgcg ccagtagcat
    11161 cacttgcaga taacactctt ctagttaaga gtaatatggc ttcatttgta gattctctag
    11221 ttccagctct tagtatttca aatgcccttg ctatatctgt tgggatgaag gaaaaagaag
    11281 atattaaaca gcattttgat gatttagagc aaatttggaa aagatattct gtgtatgagt
    11341 aaagtttgta tattaataag gctatgaaat tgagaatcat agccttatta gtaaatactc
    11401 gattatcact taaaaaataa attttcgttt aaataataca aataaatatt tcgagactca
    11461 aaacataaag atgtattctg aatacatctt tactacgtca actaatttat taaagaaagc
    11521 atttccattc atggagagtg ctttttttat ttctctaaac aatatcattt ccttaattaa
    11581 caattataaa attaatttta ttt
//
LOCUS       DAEPXW010000112        11474 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.115, whole genome shotgun sequence.
ACCESSION   DAEPXW010000112 DAEPXW010000000
VERSION     DAEPXW010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11474
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.115"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     regulatory      241..284
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            385..1353
                     /locus_tag="KRM55_003116"
     CDS             385..1353
                     /locus_tag="KRM55_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBH1595326.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKEFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            1355..1918
                     /locus_tag="KRM55_003117"
     CDS             1355..1918
                     /locus_tag="KRM55_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1595327.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            1926..2615
                     /locus_tag="KRM55_003118"
     CDS             1926..2615
                     /locus_tag="KRM55_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1595328.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            2742..3470
                     /locus_tag="KRM55_003119"
     CDS             2742..3470
                     /locus_tag="KRM55_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH1595329.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAQDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            3484..4158
                     /locus_tag="KRM55_003120"
     CDS             3484..4158
                     /locus_tag="KRM55_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1595330.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            4184..5020
                     /locus_tag="KRM55_003121"
     CDS             4184..5020
                     /locus_tag="KRM55_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595331.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            5036..5707
                     /locus_tag="KRM55_003122"
     CDS             5036..5707
                     /locus_tag="KRM55_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595332.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLINQNIY
                     DLVILDLMLPNINGFDILKKMRINNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            5697..6929
                     /locus_tag="KRM55_003123"
     CDS             5697..6929
                     /locus_tag="KRM55_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595333.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            7079..7396
                     /gene="trxA"
                     /locus_tag="KRM55_003124"
     CDS             7079..7396
                     /gene="trxA"
                     /locus_tag="KRM55_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH1595334.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            7413..8291
                     /locus_tag="KRM55_003125"
     CDS             7413..8291
                     /locus_tag="KRM55_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1595335.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            8561..8929
                     /locus_tag="KRM55_003126"
     CDS             8561..8929
                     /locus_tag="KRM55_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1595336.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            8932..9303
                     /locus_tag="KRM55_003127"
     CDS             8932..9303
                     /locus_tag="KRM55_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBH1595337.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(9447..9902)
                     /locus_tag="KRM55_003128"
     CDS             complement(9447..9902)
                     /locus_tag="KRM55_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595338.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(9941..11206)
                     /locus_tag="KRM55_003129"
     CDS             complement(9941..11206)
                     /locus_tag="KRM55_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBH1595339.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         4620 a         1199 c         1896 g         3759 t
ORIGIN      
        1 tgttattaat tgtaatattt aagatattat tgtataataa taatcggttt aaatgcgcca
       61 catcttatta aagttggttc ataattctaa ataaacttta ataagataca ttaaaatata
      121 ataaattctt ttatgctata aaatttattt tatagctatt aaatcagatg tttaaaaatt
      181 ttttaacagt ctatagtttt taagagtcta tagtaagtag actaaaaata tgattttaca
      241 tctgtacttg ttcgagaact ccaagtataa aaaactaagg aattatatag tggcagtata
      301 taattaatac ccttagacac acctttttga aagtggaaaa aagatgtgta gttctcctcg
      361 accacaaatc aaggaggata aaaaatggaa aagagaaaag taataattga ttgtgaccca
      421 ggaattgatg attctttggc aattcttctg gctttaaact caccagagct agaagtaatt
      481 ggaattacca catgttgtgg aaatgttcca gccaatatag gtgcagaaaa tgcactaaaa
      541 acacttcaaa tgtgttcttc actaaatatt ccagtatata taggagaaga agcaccacta
      601 aaaagaaaac ttgtaacagc tcaagataca catggagaag atggtattgg agaaaacttt
      661 tatcaaaagg ttgtaggagc taaagcaaaa aatggagcag tggattttat aataaatact
      721 ttacataatc atgaaaaagt atcaataata gcacttgcac cacttacaaa tatagctaaa
      781 gcacttatta aagataagaa agcatttgaa aatctcgatg agtttgtatc tatgggagga
      841 gcatttagga ttcatggaaa ttgctctcca gtagcagagt ttaattattg ggtagaccca
      901 catggagcag attatgttta caagaattta tctaaaaaaa tccacatggt aggtttagat
      961 gtaactagaa aaattgtact tactcctaat attattgagt ttataaatag acttgataag
     1021 aagatggcaa agtatataac tgaaataact agattttata ttgatttcca ttgggaacag
     1081 gagggaataa ttggctgtgt gataaatgac cctctagcag tagcatactt tatagataga
     1141 agtatatgta aaggatttga atcatatgta gaagttgtag aagatggaat agctatgggt
     1201 cagtctatag tggattcttt caatttctat aaaaaaaatc ctaatgcaat tgttctaaat
     1261 gaagttgatg agaaggaatt tatgtacatg tttttaaaga ggctttttaa aggttatgaa
     1321 gacattatag actctgtgga aggagtgata tagtgtgaaa agaaaaatat gtgtaaaaac
     1381 tattacactt atagcttttg gtatttctat aaatataata ggcgctttta tagctatggg
     1441 attaagatta cctgtatact tagattcaat aggaactata atgatagctt cacttttagg
     1501 acctaaatac gctgttgtta caggtgtgtt tggaagttta ataagtggaa ttacgtttga
     1561 tgtgtattct ctctattttg caccagttca aatatcaacc ggattacttg ctggaatagc
     1621 atttaaaaag aattttttaa ggggtttaaa aactccacta ggagtacttt tatttgccat
     1681 tccaacatct ataataagtt caataatttc agcattttta tttggaggta tgacctcttc
     1741 aggttcatca tatatagtgc aaatcttgaa agtgttagga ctgggggatg tttttagtgt
     1801 gtttgtaacc caagtattta ctgattatgg agataagctg ttagcagttg ttttagtgaa
     1861 tttaggatta aatgcagttc caaaaacttt aaaggtatca ttgactggag gaaaatagat
     1921 agaaaatgga tagatatagt gagataacaa ataaaaatca aagagaaatt gttctgctta
     1981 aaggatttcc ttgtatatgg ggaaagtgtt ctttttgtga ttatatagat gataattcta
     2041 atttagaaga agagatgaat aaattaaatc taaaggtttt aaaaaacgta actgggaaat
     2101 atggagttct tgaagtcata aattctggaa gctgttttga attacctaag gatactttag
     2161 aaaaaataaa gtgtattata aaagagaaga atataaaaaa attattttta gaaagtcatt
     2221 ggtcttacaa aaataggctt aaggaaatga gagagtattt tgaaattcct gtggtattta
     2281 aaattggagt tgaaaccttt gacaatgatt ttagaaataa tattttaaat aaaaatgcaa
     2341 attttaagac tccacaagat gtaaaagaat attttgattc accttgtatt atggttggaa
     2401 taaaaggaca aacaaaagag atgatagata aagatataga gattatccta aatacttttg
     2461 aaaaagcgac agtgaatgtt tttataaata attcttctag tataaaaaga gatgaagagt
     2521 tagtgaaatg gtttgttagt aagtataaat tcttggatga aaatccaaat atagaagttt
     2581 tatacaataa tacagacttt ggtgtaggag attagcatta atttagttta aatttaaaat
     2641 tgaaaagttt cttatgtttt tgaaaaagct tctaatagtt agaagctttt tttgtagagt
     2701 tttatgttac aataagaaaa aaggaattaa ggagcaatta aatgatgttt gataggggaa
     2761 aatggaataa attggattat aatgaacttt tagaatatat gatgtctata caagatataa
     2821 aatatagaga ttttaataaa aagcttatac ctggaacaga aaatataata ggtattagag
     2881 ttcctaattt aagaaagtta tcaaaagaaa taagccaagg gaattggaag gaatttttag
     2941 aagtagcaca ggatacatac tatgaagaag ttaggctaca aggtatggta attggcaata
     3001 taaatagtaa ttttgaagaa actttatact atgtaaaaag atttatacct aaaatcgata
     3061 attggtcagt ttgcgatgga ttttgttctg atttaaagtc tatgaaaaaa tataaagaaa
     3121 atatgtatga tatacttaaa aaatatgttt attcaaagaa tccatgggaa attagatttg
     3181 cattagttat gtttttaata tattatgttg atgataaaca tattaaagaa atatttgaat
     3241 actgtaataa tatacaaagt gaagaatatt atgttaaaat gggtatggca tggttgctat
     3301 caatttgttt tattaaatgt gaagaggaaa cttttctcta tataaaaaat aataatttag
     3361 atgatttcac ttataataaa atgctacaaa aaataattga atcaaataga gtagatttag
     3421 aaaagaagaa tataataaga agtatgaaaa gaaagacaag aagatgttga cggaggaata
     3481 ttaatgaata acaatgaaga cagaattgac aaatttttag aacttcaaag caaaggattt
     3541 aaatttgcag agatagctca aaatctaaag attagtcaaa gtactttaag aactttttta
     3601 aataaaaaag gatataagtc agaaaaaggt aaatacatat taaaagacga attaaattat
     3661 aataaaagtt tggataatag aaacttggaa gaagagaaag ctaaggagta tgaaaaaagt
     3721 aaaaagaata ctataagtaa tagaaaaaaa gtaagcacca aaaaaaagat ttctaatgaa
     3781 aaggctttaa gtaaaagtgt tgaacaaatt gagtttaatg atacaggttt aaaaaatgca
     3841 aagccaaaac aaaatattaa gcctaagaaa gatagaaaaa taaatataac tcaagaagat
     3901 ttagataagc tttgtgaagt atatgattgg tatttagaag taaaagatta caatataaag
     3961 cctaaaaaag tatctaataa aaaagatgta catatagatg atgaacacat agatgaatta
     4021 aaaacaacaa gaatacgtat agataaagaa atatggaatg attttgaaag attatgtagt
     4081 aattcgaatt ttgaaaaaca tcaaatactt acacaggcat tgaaagaatt tatgaaaaag
     4141 tataaaaatc tactataaaa tactactata tgaggtgctt aatatgaata aaatagtaaa
     4201 aaaatcaatt tctctaatga ttatattaac aatatttatt tttatgttga cagcatgtga
     4261 aaaagatgaa cagcctgatt cagttgatat tcaaacagaa gataaaaatg agataaaaat
     4321 agatgaggga aatgcaaaag tattgaatat aggaaaatca gaaattataa atatagatga
     4381 aggtgataaa gtagatacat caacaaaggt agaaaataat tcaacattta atatatccaa
     4441 tgttgaattg atatataatg aatatgatga gaataaaaaa attatatctt cggatagtaa
     4501 ggctttgttg gacatgactt taatgcctgg gaaagttgct tacatagaat gtgggcataa
     4561 aacttttgta aagggtgtag aagtttatgc atatgaatat gaggcagagg gtaagattgt
     4621 gtatgttaat ttaaaagaaa atactattaa tataagaaat aataatatta agctagaaaa
     4681 tagtagtcag tatgaggtgc tatctacatc agaacttaaa aaagtaaatg aatcaaatga
     4741 gggaattacg tatcaagtaa aagtaaaaaa ttcatcatca aaagatttag gaaatattat
     4801 tcttaagaca gcagaagtta atgaaaatgg agaatattta acagtaaatc gtgtaccatc
     4861 atataagatt ttaaagcctt cagaagagac agatatagat atattgtgtt caacaaaggc
     4921 aaaaagtgtt gaaatagtgg gatatacgta tgatgatata aaagaaaaag ccaatgtgga
     4981 tattgactta aaatctcata aagttaagat agacaaataa aggtagggga tacttatgaa
     5041 ggttttaata gttgaagata ataagatact tttagaaagt gtagtagaag aacttagcaa
     5101 gcattttgaa actgaaaagt gtgaagatgg agaagaagct ttatacttaa taaatcaaaa
     5161 tatatatgat ttagtcattt tagacttaat gcttcctaat ataaatggat ttgatatcct
     5221 aaagaaaatg agaattaata atatagatac acctgtactt atattgacag caaaagaaac
     5281 attagatgac aaagtagaag catttactat aggagctaat gattatttga caaaaccttt
     5341 ttatatggaa gagttagtag ctagggtata cgctatatta aggactaatg gaaagataaa
     5401 agaaagaaac ggattagaat ttaaatcttt atatttagat acactagaaa aaagagtgta
     5461 tattgaaaaa gaagaaataa aacttcaaaa caaacagttt aacttgcttg agtattttgt
     5521 attaaataaa ggttcaattt tattaaaaga gcagatttat gatagaatat ggggaattga
     5581 ttcagatgca actattgaaa tagtggaagt atatgtaagt aatctaagaa aaaagctaag
     5641 taaatatgga tatgataaat atattaaaac taaacgtaag gtaggatata tattcgatga
     5701 taaataagaa tgtatttacc agtactaaaa atcatttaat aaaaatgtat attattgtag
     5761 taggtagttt tttaataatc ttttctatat ttatatactc atattttagg ggacttacat
     5821 atagtggaat tgatagtgag ataaatgatg aacttgaata tatagtctct caatttaaaa
     5881 gaacttcatt tttgaaccca ataagactca aagatcctaa agatatggtg tatgtatatg
     5941 aagatggaag gataagttac tatactcaaa atgaatattt tgatgagtta cttccagata
     6001 gaagactaga taaaaaaaat tcgtttttta aatacacaga aaatggatat acttttagag
     6061 aattaaatgt agatgtaggt agataccaaa tacagataat tagaaatata gattctgaga
     6121 tgaattcttt aagacagctt acatctgttc ttataattgg aatattaatt tctgtaataa
     6181 ttacttactt tgtggctgta tatctcacta gaaaagcttt aattccaata gaaacagcat
     6241 ggaaaaatca agctaagttt atacaagatg cttctcatga attaagaaca ccaataacaa
     6301 tagtttcatc aaaattagaa agtatgttaa aatccccaga aagtacagta aatgatgaag
     6361 ttgaaacaat agctactgca atgaaggaaa ctagaagact taaaaaaatg ataactgatt
     6421 tattgtctct tactaaagag gactctattg ttaaagttaa tttagaagaa atagatttag
     6481 aaaagttatt ggaagaaata tcagaagact atattgacat tgctgagttt caggaaaaaa
     6541 gattcgtgtt taattctaaa ctgaagaata aagttataat aacagataaa aataaattaa
     6601 gacaacttat attaattttc attgataatg cctttaagta tacaaaattg ggtgatgaga
     6661 tagcattaga attgaaagaa gatatagagg atgaggtaac tttacttata agtgatactg
     6721 gtataggcat aaaaaaagaa gagatacctc ttatatttga tagatttttt agaagtgaaa
     6781 atgtaagaaa taaagattta gaaggttctg gaataggact ttcaatagct cgcatgatta
     6841 gtttaaactt atctattgat ataaatgtaa cttctgatgt agatattgga actacatttg
     6901 aattgtcaat accaaaaaag ttaaaataat aaaaatataa aaaattgttt ttagaaatga
     6961 agaatgggta tactaattag tataaaatat aaaaagacct tataaaagta aatttatatt
     7021 tataaatttc atagtataat tatataggga taataaagtt taataggagg atttaaaaat
     7081 ggcaaaagtt ataaatacat ctgaatttag aagtagtgtt gaaggtagta agggagtagt
     7141 tgtagttgat ttctttgcaa cttggtgtgg accttgtaac atgttgggac ctgtatttgc
     7201 agaattaggt gaagagatga aggataaagc tagatttgta aaagttgata tagatgagag
     7261 tttagaaata gctcaacaat tcaatgtatc tacagtacca actatgatta tatttaaaga
     7321 tggaaaacca gtagaaactt taattggatt catgccaaag aacaaaattg aaatgcaagt
     7381 aaaatcatat ttataaaaaa tgggtgagta ttatgagata tgatatagct ataatcggca
     7441 gtggtccagc tggattgtct gctgctataa atgcaaaaat aagaaataaa acaattatca
     7501 tgtttggtaa tgataattta agtaataagc ttgttaaagc tccttcaata gataattatt
     7561 taggttttta tgatataagt ggtgatgaat taaaagacaa gtttaaatca catatagata
     7621 gtatggatat ttcaattgaa aataaaagaa taaataatat ttatgctatg ggagaatact
     7681 ttacaataat gtctggaaat gatatgtatg aagctactac tgtaatcctt gcaactgggg
     7741 tagagtatac tagaccaatc aagggtgaag aagaatttct aggaagaggt gtgggctact
     7801 gtgctacatg tgatgcacca ctttatagaa ataaaaaggt agcagttata ggatataatg
     7861 aagaatctaa agaagaagca aattttttaa gtgaactcac ttcaaagact tattttatac
     7921 ctatgtacaa aaaagataat cttatgagaa gttcagataa cctagatgat tctattgaag
     7981 ttatacatga cagaccagta cagatagatg gagataaact tgtaaacaaa gtatctttta
     8041 aagaaaacca cattgaagtt gatggagtat tcgttataaa agatagtacg gctccaagtg
     8101 cattggttcc tggaatagag attgatggca ttcatattaa agttgacaat aatatgaaga
     8161 ctagtataga tggatgcttt gctgctggag attgtgttgg aaaaccctat tcttatataa
     8221 aagcagctgg tcaagggcaa atagcagctt taaatgctgt ttactattta gataaattaa
     8281 agagggctta atatttatat tgattaactt tttaaagata tttataaaaa actgtcttga
     8341 aataatttta ttatttcaag acagtttttt atttttaagt tattaataaa agtattttaa
     8401 aatctatatg taattacttt tattaataaa actcaaagtt atattagtaa aaattggaat
     8461 tatttataat atactccaaa atttaaaaat aatggttgaa aaatctaatt aagagtacta
     8521 taatttaatt aagtaattac ttaatcaaaa tgaggtactt atggaaaact tggttaaaat
     8581 atttaaagca ttgagtgatg aaactagact taacatactt atattagtat ccaagagaaa
     8641 tatatgtcaa aaggggattt ctaaatatct agggatttca gattctgctg tttcacaaca
     8701 tataaaaata ttaaaagatg ttgggataat aacaggatat aaagaaggat actatgtttt
     8761 atatcatatt aataaagaat catttaatat atgtgtagat tttataaatt ctatgttaag
     8821 taattctagt gaaagcttta tagatgtatt tgatgtaaat acaatacatc taggatgcag
     8881 taaagaatgt aaatctataa aaaaatgttg taagagaagg gagaaataat aatgaaagta
     8941 tgtataccag tagaggagaa taaaggattg gatagtaaac catatggaca ttttggttct
     9001 gctccaattt ttgttgtgtg tgatttagaa agtggagaag ttaaatcttt agataatgga
     9061 gatttagatc atgaacatgg aaaatgtcaa ccattaaaag cattgtcagg gacagctgta
     9121 gatgcagtag ttgttggagg aataggacaa ggagctataa ttaaattaaa tggaatggga
     9181 ataaaagttt acagagcaga aggtgatact ataagtgcta atttagactt acttaaaaat
     9241 ggaaaattag tagagtttcc atcagaccat acttgctcac atgacggatg tggacatcat
     9301 taaaaaaaac agctgatgaa atatatactt catcagctat tttttctttt aataaatacg
     9361 attttattct tttaaaacca aaatttagat ttttatgttt tttgtagtat ccttaataat
     9421 atttcaagtt tacaagttta ctacttttag atttttttgg tatgtttttc tatatagtca
     9481 atatcattta atatgtcatt gagttcttta ttaagtgttt ttaaatcatc accatctaca
     9541 ttgtagttta aaaatagttc ctctacatta tcaatgatag aattgacttt tctagtaact
     9601 tcaacaaatg tcttaaagtt actactattt ttagcattta gaaatttttt taaatccttt
     9661 gatataaatg atactatttc atattcatca ttaaatagac ctctaccaat aggatatggt
     9721 tcaattctct gtaaaaaata ttggtcttta gcattaatat tataagtata agatatttcc
     9781 caaccgtctc ctaaatcaaa cttgataaaa tataatgtac tacttacttt tgatattctt
     9841 gtggcaccaa gctgtcttaa aagaacttca atcgaatcac cttgaacagt attaatattc
     9901 atatatacac atccccttta gtattattat actatatttt ttaaaatttt ataattaaat
     9961 aaacagtaga tataataata gatataatca taagtggaaa acctattttg aaatactcct
    10021 taaaagagat aggatgaccg tgtttattac ctatacctgc tagtacaaca ttagcagatg
    10081 ctcctattag tgttccattt cctccaagac aagctccaag agatgttgcc caccatagtg
    10141 gcattacatc aataccttca gcttgcatag tcaaaataag aggaattagt gttgcaacaa
    10201 atggaatatt atctaagaaa gaagagacta tagctgacaa ccataatatc aacaacattg
    10261 taaatacaag atgtccttct gtaagtccaa tcaatgcttg agccaatttg tttattatcc
    10321 caacttctac taatccacca actactacaa ataatcccat aaagaataaa attgtagacc
    10381 attcaatacc tgccataatt tcatctacat cttgttttcc tattaaaagc attatagatg
    10441 ctcctgtcag tgctacaaca gaagaatcta tgtggattgt actgtgaaac ataaaaccaa
    10501 aaagtatgaa tgctattaat ataaggcttt ttataagtag aggtttatct ttaacagatt
    10561 ttttttcatc tagttttaat attgcatttt tagctctttc attcacaaca agttcttttc
    10621 cataaataaa tctaaagcat attatagtta tagcaagtat tactataaca gcaggaccta
    10681 aatttattac aaaatccata aaactaagat tggcagcact accaatcata atatttggag
    10741 ggtctcctat aagagtagct gttcctccta tatttgaagc taaaatctgt gttattaaaa
    10801 atggaactgg attaagtcct aatatttgtg taataactat agtcattggt ccaataagta
    10861 agacggttgt aacattatct aatacagctg ataaaatagc tgttataata gcaaaacaaa
    10921 tcattatctt ccatgggtca cctttggctt tctttgcagt ccagatagct atatattcaa
    10981 ataaccccga gtttttgaca acagctacaa atagcatcat accaactaat acaccaatag
    11041 tattgaaatc tatatggctt aatccttcat caagtgtaag tatattgaat attatcatta
    11101 atagtgcacc accaacagct gctacggatc tgtttacctt ttctgtaata atagctgcca
    11161 taactattaa aaatatacat atagctatta tttgttgaaa ttccataata taagtacctc
    11221 catttgtatt attttgtgcc taatgctagt actatatata gtattacttt tttattgttt
    11281 tttcaatgga tgtatgaaag tatattattt aacaaagttt ttggaaaatt gacagaattt
    11341 aaagaaaatt tttgttattt aaataaattt taaaattatt ccattgataa taatattaaa
    11401 cgacaaacga aaaaatatac cctttaaact agaatttatt gtatctaata acaattataa
    11461 aatattaaat atat
//
LOCUS       DAEPXW010000113        11163 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.117, whole genome shotgun sequence.
ACCESSION   DAEPXW010000113 DAEPXW010000000
VERSION     DAEPXW010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11163
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.117"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(<1..2356)
                     /locus_tag="KRM55_003130"
     CDS             complement(<1..2356)
                     /locus_tag="KRM55_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH1595340.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSSSGGSSSNQTSVNNEAAKITSVPTPAKDATRLTMPSVSSGYTIAIKTSSNE
                     SVIKKDGTIIPPNTATTVKLVFTVTHTSSGKTADTKELSVTVPAKSTDEELQAALDNE
                     VAKITSVPAPAKDATKLTMPSVSSGYTIAIKTSSNKGVIKEDGTIIPPNTEETVTLVF
                     TVTQESSGKTADTGEIDVVVPAKSTDGEIQAEVQAEADKITSVTQPTQDATTLTMPTV
                     ASGYTIKIKSSTNESVIAKDGTIIPPNTETKVTLVFTVTHTSSGK"
     gene            complement(3140..3328)
                     /locus_tag="KRM55_003131"
     CDS             complement(3140..3328)
                     /locus_tag="KRM55_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595341.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            complement(3354..4493)
                     /locus_tag="KRM55_003132"
     CDS             complement(3354..4493)
                     /locus_tag="KRM55_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1595342.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKIIEDKNDLALESYYSSVIEGAFSNRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HIGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKEFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICSKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            complement(4919..5239)
                     /locus_tag="KRM55_003133"
     CDS             complement(4919..5239)
                     /locus_tag="KRM55_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
                     /protein_id="HBH1595343.1"
                     /translation="MASSKDYLQFVLEQLSELQEITYRAMMGEFIIYYRGKIVGGIYD
                     DRLLVKPTKSAISYMPTVTYEIPYENAKEMLLVEEVDNKDFLTGLFDVMYDELPTPKP
                     KKKK"
     gene            complement(5266..5661)
                     /locus_tag="KRM55_003134"
     CDS             complement(5266..5661)
                     /locus_tag="KRM55_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011068146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC family protein"
                     /protein_id="HBH1595344.1"
                     /translation="MAISNINTIISNDIQKVWNIVLAVDKYNSWRSDLSKTEIINDKQ
                     FIEYTKNGYATTFTVTVAEPYKCWEFDMENSNMKGHWIGVFIDKGNETQIDFTENVIP
                     KKWFMKPFVKTYLKKQQKQFVLDLKKALE"
     gene            complement(5703..6209)
                     /locus_tag="KRM55_003135"
     CDS             complement(5703..6209)
                     /locus_tag="KRM55_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008977829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595345.1"
                     /translation="MDFRQAIMRDLPQLKDMYKRIIQNMNEQDIQIWDDVYPCEFFEE
                     DIKNNQLYVLLNNGEIVSAFVLSNTNSGEDAVKWNDNHAEAIYIDRLGVNIKYSKKGI
                     GSLMLDKAKEIAKTLDAKYLRLFVVDRNIPAIQLYIKNGFVKVDGVYDEVFDDGFVLH
                     EYGYEIKL"
     gene            complement(6434..6913)
                     /locus_tag="KRM55_003136"
     CDS             complement(6434..6913)
                     /locus_tag="KRM55_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015567246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HBH1595346.1"
                     /translation="MANEDKKDFNAMLHDSKDMPKFQIIIDQKSIEKYGGNKMYFAPP
                     IDYDKVMKKVPYGKVITVGKIREHFAKLSGADFTEPITAGIFVSIVAWASYQRSEDET
                     PYWRTLKANGELNAKYPNGIEAQKEKLEAEGHTIIQKGRKNIRYYVKDYENSLFDLK"
     gene            complement(7224..7895)
                     /locus_tag="KRM55_003137"
     CDS             complement(7224..7895)
                     /locus_tag="KRM55_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595347.1"
                     /translation="MEHYEKKISFLGENIQTIRKHRGMKQQELADKIGINMQSLSKIE
                     RGVNYPTFDTLEKIMDVLGVTPNELLLGEWKYIDHTEPYIMDIIKREQDFNVSLDYLS
                     ENEFFDDEKECTFYKAYKLIQYIHNYITNEVTELEELMEIKQLIQRQKLERMIKVHKE
                     MRGLDRYREQPKEYKYHDPYDDWIFRQLADIDNRNNIPDTSPQVDFNEADYEDYLKAK
                     WNRGL"
     gene            8362..9453
                     /locus_tag="KRM55_003138"
     CDS             8362..9453
                     /locus_tag="KRM55_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018594174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBH1595348.1"
                     /translation="MTTHKNLSVKIDYISIVFETATAEDVIMHILDLPTDIFNVYPAT
                     IKFKTYQARWQIGDIYVSGDARKTEDNPQGLGCYLVMTGRGCDDIFRILDSRNYTFGD
                     MFRRCERRYGLDNFHFTRLDIAIDDKNEKPFFTIEQIKKKCEKEEFISNSEGYHFDES
                     KFDDFDTAKTVYIGAGKSGLSYRFYDKDKEVCSKHNKTLDEVGSWKRTEMQLRDDKAH
                     AFAMTFKDRPLELGELAFGLLANNLRFVVPNRNESNKSRWKTCRFWERFLGAMEVLKL
                     QVPKLHNSLEETQQWLTEGGVISAVKSFYFLEEHDALGGLEKVGTMLDKARYSNSLSS
                     KLTAHLQRIDRTDLIPYIQYNTKHGKGGI"
     gene            9453..9656
                     /locus_tag="KRM55_003139"
     CDS             9453..9656
                     /locus_tag="KRM55_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1595349.1"
                     /translation="MNNNDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWLI
                     MNGNRIQIKRRQFEKVIDKLDAI"
     gene            9735..10928
                     /locus_tag="KRM55_003140"
     CDS             9735..10928
                     /locus_tag="KRM55_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1595350.1"
                     /translation="MKEKRRDSKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKRDKLSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVLENDTKKKVALTEEQEQALLSFIKTDNVYHKYYDDVLI
                     LLKTGLRISELCGLTVTDIDLKNEVVIIDHQLLKSKEQGYYIETPKTKSGTRQVPLSR
                     ETIQAFQRVMKKRPKAEPFVIDGRGNFLFVNPKGKPKVAIDYSTLFVRMVKKYNKHHM
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
BASE COUNT         3475 a         2017 c         1646 g         4025 t
ORIGIN      
        1 ttttaccact tgatgtgtgt gtcactgtaa atactaatgt tacttttgtt tctgtatttg
       61 gaggtattat tgttccatct ttcgctataa cactttcatt tgttgatgat tttatcttta
      121 ttgtgtatcc acttgctact gttggcatag ttagtgttgt tgcatcttgt gttggctgag
      181 ttacacttgt tattttatcc gcctcagctt gtacttctgc ttgtatttcc ccatctgttg
      241 atttggctgg tactactaca tctatttctc ctgtatctgc tgttttacca cttgattctt
      301 gtgttactgt aaataccaat gttactgttt cctctgtatt tggaggtatt attgttccat
      361 cttcctttat aacaccctta ttgcttgatg tttttattgc tatagtatat ccacttgata
      421 ctgatggcat agttaattta gttgcatctt ttgctggtgc aggaacgctt gttatttttg
      481 ccacttcatt gtctaatgct gcttgtaatt cttcatctgt tgatttagct ggtactgtta
      541 cagataattc ttttgtatct gctgttttac cacttgatgt atgtgttacc gtaaatacta
      601 attttactgt tgttgctgta tttggaggta ttattgttcc atcttttttt ataacactct
      661 cattacttga tgtttttatt gctatagtat atccacttga tactgatggc atagttaatc
      721 tagttgcatc ttttgctggt gtaggcacgc ttgttatttt tgctgcttca ttatttactg
      781 atgtttgatt agaagaactt cctcctgaag atgagcctcc tccatgtgaa gaacctccac
      841 ttgatgaact tcctcctgaa gagttagaac ttggactatt tccacttatt gttggagaat
      901 tatctccctt aacactactt attgtacctt tattatctat agtagtccct ttagaattat
      961 ttgtaactgt agttatctta ccaccattag tcacttttac ttgacttgct ccagatgcta
     1021 ctgttaaact accaatctca cctttagaat tattttctat cttggctcca tttttatcat
     1081 taacctttaa gttagttatt tttccatagt taacaaaagt tccatctttt acatcatcta
     1141 taactacatc atccactttt gcatagttat ttacatctcc attaggcatg ttgatagtta
     1201 cagtctttgt atatgtacca tttaagttta ctgttactgc tttatcagtt tgtattgtaa
     1261 atgcttcttt aacctcacta gttggcttaa agtttataac atcattagca gtagctttat
     1321 ctatagctga ttttaattca gaaattgttt tagcttcaac tgtttttact tcttgtaatg
     1381 acttcatttc attaaatgct gtctcattac cattcccacc aactttagtt atcttatcaa
     1441 aactcttaga gttaactaga gatttttgtg aagctgataa gttctttcca actaaaacta
     1501 ctggtgattg atttttagca cctaatacac ctactgctag tgcatctata agttggtctt
     1561 gtttattcat accatcttta gttacataag cattttttaa atctgtcttt ttataaaatt
     1621 cttttattac ttttgcattt gtatcatttc tatctgttcc acctagtctt gtactatttg
     1681 gtagtttatt tttaacagct tcagaaattg aactctctcc acctactaca taagattgag
     1741 ttattccagc atcttttata aatttgtctg caactgctgt tccattttta gaatcagcaa
     1801 gtattactgg catattgttt tgtgcagctg gtgctcctac acttacagca tctgcaagtc
     1861 ctttttcacc attaactaca gctattttct taacatcact tatagcatct aatttctttg
     1921 ctaattctaa ggatgtttga tatctctcag ctccagagat tctctcaaaa gatattttta
     1981 aatcttttat ttctttttct atatttgtac ttaatacaga agttccacct attaagtata
     2041 cttttttagc ttttaatctt tgtatttctg ctttcgtctt atcatttaat ttatctttac
     2101 ttgttaaaag tattggagca ttttttgctt ttgcaaatgg tgttgcagat agagcatctg
     2161 ctatagatga gtcgtttacg attactacct catcagcatt tttccatcca tcttgactta
     2221 ttttaacagc agtttcatat ctttcttgcc ctgttaaatt tgttgccaca gtttgtgcac
     2281 tagctatgcc tgctgttgaa cttccagcta tcattgtaac tgtaagcatt gcagcaatct
     2341 tctttggtat tttcatttta ttttcttccc ccttgtccat ttgatattac ttaatttttt
     2401 aactttgttc ccgttctaat tctaaaggat acttaatatc taattttaaa gaggtttcta
     2461 actataatga tttcataatt aatttgtaat tattttgtta cattgcagtc attatgtaag
     2521 gaataaagaa attttcttat tgattgaaaa atttgtaaat ttatatttta aggtaagttt
     2581 gatttttatg ttaatgaatt gttataaaaa atagggtttt gtataaaaaa agtagccttt
     2641 agaattaaaa gtgctactct ttttacaaat aaattttatt atttatactt gtaattatat
     2701 attaaataac caattttatc catatgaaaa acaaataatt acgatatttt tttaattatt
     2761 ctttatattt acattttaat tcaaattact tttgtaaaga ttatatctgt tgcatatact
     2821 actttaagtg ctaatatatc tccccctaaa ttagaatcct cgttatctca atagacgttt
     2881 tctactgtca aagttaccaa catttgaaac ttattaaatt tttatataaa aaagacctag
     2941 aatataaatt ccaagtcatt ttttattaaa tttatttttt acaatataat attgtcatga
     3001 ttaaagaaca caaatcatac acaaattggt cataaatctt acataaatca tctacaaaaa
     3061 atacattatt tatattaaat ctatataact aaattaagag catattgtac aatatgctct
     3121 tagaaaagat atttcttgtt tatagtttat agtatttctc tatgattttt atttttatca
     3181 tttcaaaaat aaaaattaag attacagtta ttatcatatt ttgtgtacta ttttctataa
     3241 tattataatg aaacaatgaa aaaacaataa ttaatgaaat tacgtttata gccccagaaa
     3301 tcaaaaatgc ctttttctta ttattcatat attccctctc cagattatct aaactagtct
     3361 atatcaagca tttttaagta cttatcatta actttatata tatttttttc tttagacaaa
     3421 atctctatct cttcaagatt attaaacact tccatcaact ggtcaactaa ttcaatttcc
     3481 tttattccag cctttaagta tctactttta ttctttttta tataattttc taatgtcata
     3541 gaatagttat ctttactaca gatatatttt aatatatgtt cttctgttgc tgatagagtt
     3601 atgtcatttt caaacaattc ctcttttaat atactttcta aagattttct atcatgcata
     3661 ttacgcatct cattaataga ttgtattata gacttgagca taaactctat aaatacagtt
     3721 aaattatttc ctttgttttc tacatcaagt atagccttat aatacttagt tctgttttta
     3781 gatatcatat atgatattga aaactccttg aaagtatcat atcctttatc aatcaaatat
     3841 agatatgata aggctcttga tgttcttcca ttaccatcac taaaaggatg aacatataca
     3901 aagtaaaaat gaattatagc acttttaatt aaattactta ctttgctatt ttccataaaa
     3961 tctattaatt tactcataaa gtcatatatc ttcaaaggtt caagccctat atgtataatc
     4021 tcaccttttg aatcacatac atatactttt tcagttctat actcatattc ttctgaatcc
     4081 aagcagtttt cgcccaatat atgatgcaaa tcatatataa atttgtgact atataattta
     4141 tctaagttgt ctaatccata ttctaaggct ctatgattat tgtaaatcat atattcactt
     4201 ttattacttg gtttcatctt tcctctaatt atagattttg caatctttct atttgaaaaa
     4261 gcaccttcta ttacactaga ataataagac tctagtgcca aatcattttt atcttctatt
     4321 attttaaata tcttacttga tgttaattta tctatttcat ttattaaatt taatatattt
     4381 tcagtttcat gatagtatag ttctttatta tcaaaactat ttatagaaag tacgatttta
     4441 tttccagtaa agtatttgtt tttgtattct tctattgtca gtttaatcac caccttagat
     4501 tatctttatc tattaatatt aacaaaaagt attaattttt acactatttt tgattatttg
     4561 ttttataatt atcaaactca atttaacgtt aaagcataat aaattttaat aaataatgca
     4621 aaaatttaag aataagcatt taaaatatat gtcacaggaa gtttacaact attatttata
     4681 ataaatttta tatctaattt tcgattatcc gcataaacac tatactttca agtattttga
     4741 agtatagaaa aaactcattt taccacgaat ttaccacgat tgaatgagcc ttgatatgac
     4801 ctataaaata acacccaaaa gacatcatta cacctaaatg gtgtcttttt aaaaagcagt
     4861 caatcctaaa actaactgct ttgtgtatat ggatatgaaa ttgtaaacta gaagctgttt
     4921 attttttctt tttaggtttt ggcgttggta gttcatcata catcacatca aataaccccg
     4981 tcagaaaatc tttattatca acttcttcca ccaataacat ttctttggca ttttcgtatg
     5041 gaatttcata agtaactgtc ggcatataag aaattgcaga ctttgttggt tttacaagta
     5101 acctatcatc atatataccg ccaacgattt ttccacgata atagataata aattctccca
     5161 tcattgcacg atatgttatt tcttgtaatt ctgataattg ttctaaaaca aattgtaaat
     5221 aatctttact tgaagccatt tccaaccctc caatcttgaa ttttattatt ccaatgcttt
     5281 ctttaagtcc agaacaaatt gcttttgttg ttttttcaaa taggttttta caaaaggttt
     5341 cataaaccac tttttaggta tcacattttc tgtaaagtct atttgtgttt cattcccttt
     5401 gtctataaaa acaccaatcc aatgaccttt catgttgcta ttctccatat caaattccca
     5461 gcatttatac ggttctgcaa cggtaacggt aaatgtagta gcatatccat tttttgtgta
     5521 ttcaataaat tgtttgtcat ttattatttc tgttttgctc aaatcacttc gccatgagtt
     5581 atatttatca acagctaaaa caatgttcca aactttttga atatcattac taataattgt
     5641 atttatattt gaaattgcca ctttttcatt tccccttttc aaactgaaat ttgtaaaact
     5701 tattaaagtt ttatttcata gccatactca tgtaatacaa aaccatcatc aaatacttca
     5761 tcgtaaacac catcaacctt tacaaacccg tttttaatat acagttgaat tgccggtata
     5821 tttctatcta ccacaaaaag tctaagatat ttagcatcaa gtgttttggc gatttctttt
     5881 gccttatcaa gcattagact acctatacct ttttttgaat atttaatatt tacacctaat
     5941 cgatcaatat atatagcttc cgcgtgatta tcattccatt taaccgcatc ttctcctgag
     6001 tttgtattgg acaaaacaaa tgccgatact atttcgccat tgttaagcaa aacatatagt
     6061 tgattatttt ttatatcttc ctcaaaaaat tcacaaggat aaacatcgtc ccaaatttga
     6121 atatcctgtt cattcatgtt ttgaataatt cgtttataca tatcttttaa ctgtggcaag
     6181 tctcgcataa tagcttgtct aaaatccatc ttatcacctc gttcaatttc aatttgtcgc
     6241 tttcttcata tccacattat atcattttca tatctgcacc acaataaaat tttatgcacc
     6301 gataatctta ttgaacagct ctaacaaaca ccatttcatc actccaatct gaaattttgg
     6361 taagaaaaaa gcagtcaatc ctaagactaa ctgctttgtg tatagagata tgaaattgtg
     6421 aaatagaatt tgcctatttc aaatcaaaaa gagaattttc atagtccttt acatagtatc
     6481 gtatattttt acgccccttt tgaataatgg tatgtccctc tgcttctaat ttttctttct
     6541 gtgcttcaat accatttgga tatttagcat ttaattctcc gtttgctttt aatgttctcc
     6601 aatagggtgt ttcatcttcg gaacgctgat aactcgccca cgctacaata gaaacaaata
     6661 tacccgctgt aatcggctct gtaaaatctg caccactcaa ttttgcaaag tgttctcgta
     6721 tttttccaac cgtaatcact ttaccatacg gaactttttt cattactttg tcatagtcaa
     6781 tcgggggagc aaaatacatt ttgtttccac catatttctc aatacttttc tggtctatga
     6841 taatttgaaa ttttggcata tccttactat catgcaacat agcattaaaa tcttttttat
     6901 cttcatttgc catttgtgcc acctcctact ttaaggatag tctgtttctt atttccatgc
     6961 aatgaggctg tttgaaaatt attaacactt tcaaatttgt cgctttcttc atatccatat
     7021 tataacagtt ccatatatcc gccacaataa aaatcagcat acccttagca tttatggaac
     7081 aaaaatgcac actttttctt tcttcctctt gattacccca caacagaaaa gaaaaagccc
     7141 tgtcaagagc cttgccacca ttggtggtgc tttgcactct ttactgggct ttttgtttgc
     7201 tgtatcttcc atgcaagagg aaattaaaga cctctgttcc atttcgcctt tagataatct
     7261 tcatagtctg cttcattgaa gtctacttgt ggagaagtgt cgggaatgtt gtttctgttg
     7321 tctatatccg caagctgacg aaatatccaa tcatcataag ggtcatggta tttatactct
     7381 ttgggctgtt ctctgtatcg gtctaaccct cgcatttcct tatgtacttt tatcatgcgt
     7441 tccagttttt gacgctgtat caactgcttg atttccataa gttcttccaa ctccgtaacc
     7501 tcattggtaa tgtagttatg gatatactgt atgagtttat atgccttgta aaatgtgcat
     7561 tctttttcat catcgaaaaa ttcattttca gacaggtaat ctaaggaaac attgaagtct
     7621 tgttcccgtt tgataatatc catgatatag ggctcggtgt ggtcaatata cttccattct
     7681 cccaacaata attcattggg tgttactccc agcacgtcca ttatcttttc cagcgtatca
     7741 aaggtaggat aattcacgcc acgttcaatc ttggaaaggc tttgcatatt gataccgatt
     7801 ttgtccgcaa gttcctgttg tttcattcct ctatgctttc ttatggtctg tatgttctct
     7861 cctaagaaac tgattttctt ttcgtaatgc tccatgactt agtataaaca ctcctttcat
     7921 tgcttttctt ggtatttata agcatatcat acttaatata tatctaaaag tcaacaaaaa
     7981 cttcttgaca agtaattcta atggcgttat tatcgtatca gatagagtga ttaagcacgc
     8041 tagggtcaat cacacgcttg agtaagcata gaaaagatgt attttcattt tgatagcatg
     8101 aataagcata gactatcaga ccgaaaataa ggtttctgac tggggctgtt ccgtttagcc
     8161 acgagcctta caaggctcgt gagcgttaag aacggatcag acacaggaag aaagggaacg
     8221 cctttaggcg ttcataaagg gcgtatatgt aacaccgccc tgcgtataca tgtcatagta
     8281 cctagaaact gtgataaata aaggaaaaaa cacaattttt accccgcaaa aaaacggggc
     8341 atacgaaagg agaaatgcac tataactaca cacaaaaatt tatccgttaa gattgattac
     8401 atcagcattg tatttgaaac ggcaaccgct gaagatgtaa tcatgcacat tttagattta
     8461 ccgactgaca ttttcaatgt ttatccagca acgataaaat tcaagactta tcaggcacgc
     8521 tggcagattg gagatattta tgtatcgggg gacgcaagaa agacagagga caacccacag
     8581 gggctaggct gttatcttgt tatgactggc agaggttgtg atgatatttt ccgtattctc
     8641 gacagtagga attatacctt tggggatatg ttccgacgct gtgagcgaag atacggactg
     8701 gataatttcc atttcacaag acttgatatt gccattgatg ataagaacga aaagccattc
     8761 tttaccatag agcagataaa gaagaaatgc gaaaaagagg aatttatttc taatagtgag
     8821 ggctaccact ttgacgaaag caagtttgat gatttcgaca ctgcaaagac tgtttatatt
     8881 ggtgctggta aatcgggatt gtcctaccgc ttttatgaca aagataagga agtctgttca
     8941 aaacataata agacacttga tgaagtcggc agttggaaac ggacagaaat gcaactgcga
     9001 gatgataagg ctcatgcttt tgccatgaca ttcaaagaca gaccgctgga acttggggaa
     9061 ctggctttcg ggctattggc aaacaaccta cgctttgtcg tgccaaacag aaatgaaagt
     9121 aataagagca gatggaaaac gtgtcggttt tgggaacgct ttttaggggc tatggaagtc
     9181 ttaaaactgc aagtaccgaa actacataat tctcttgagg aaacacagca atggctcaca
     9241 gagggtggcg tgatttccgc tgtgaaaagt ttttacttct tggaagaaca tgacgcatta
     9301 ggtggactgg aaaaagtggg aactatgctt gataaggcaa gatacagcaa ttccctttcc
     9361 agtaaactaa ccgcccactt acagaggata gaccgcaccg atcttatccc ctatatccaa
     9421 tataacacga aacatgggaa agggggtatc tgatgaataa caacgatatt cccgtatggg
     9481 aaaaatacac ccttaccatt gaagaagcgt caaaatattt ccgtatcgga gaaaacaaat
     9541 taagacgctt ggcagaggaa aacaaggacg ctggctggct cattatgaat ggcaaccgca
     9601 tacagattaa acgccgacag tttgaaaagg tcattgacaa attggacgca atctaatgca
     9661 aatgagcctt gtatgtgtta tgatgaacac aagtcatatc aaggctcttt ccaacaagga
     9721 aaggagcaga caccatgaaa gaaaaaagac gggatagcaa aggacgtatc ctgcatactg
     9781 gagagagcca acgaacagac ggaaaatact tatataaata tgtggacgca tttggaaaca
     9841 caaaatatgt gtatgcctgg agattgacac ccacagaccc aacaccaaag ggaaaacggg
     9901 ataaactctc acttcgtgaa ctggaacagc agataagacg ggatattgag gacggtatcg
     9961 acagcacagg caagaaaatg acgctttgcc aactctacgc caaacagaac gcacagaggg
    10021 caaacgtgaa gaaaagcaca caaaaacagc gggaacaact tatgcggtta ttaaaagagg
    10081 acaagttagg tgctaggagc attgatacga taaaaccctc tgacgctaag gaatgggcgt
    10141 tacgcatgaa agacaaaggc ttttcctata acaccattaa caaccataaa cgctcgttaa
    10201 aagcgtcatt ctatatcgcc atacaagacg attgtgtaag gaaaaaccct tttgatttca
    10261 agttaagtga agtcctagaa aatgatacca aaaagaaagt cgcattgaca gaggaacagg
    10321 aacaagcctt actctcattc atcaagacgg acaatgtgta tcacaagtat tatgatgatg
    10381 tactgatact gttaaagaca ggacttcgta tctcggaact gtgcggactg acggtaactg
    10441 atattgactt aaagaatgaa gtcgtgatta tcgaccacca gttattaaag agcaaggaac
    10501 agggttatta cattgaaacg cctaagacaa agagcggaac taggcaagtg ccattaagca
    10561 gagaaacgat acaggcattt caacgggtta tgaagaaacg cccaaaggca gaaccatttg
    10621 tgatagacgg acggggcaac ttcttatttg tcaatcccaa aggcaagcct aaagttgcga
    10681 ttgattacag cactttattt gtccgtatgg taaagaaata caacaagcac cacatggaca
    10741 accctttgcc acatatcaca ccgcatacgc ttcgccatac gttctgcaca agactggcaa
    10801 gcaagaacat gaacccgaaa gatttacagt atatcatggg gcattcaaat atcagtatca
    10861 caatgaactg gtatgctcat gcgtccatag atactgcaaa atcagaggtt cagcgtctaa
    10921 tcgcatagaa gtatttacca cgattttaac cacgcttgat agcgaaaata taagaagata
    10981 gacctagata tgtgaggttt acaacaaaag caaaatgccc gtagagccga taaaataagg
    11041 ctttacggac atttaagaag atataaaaag atagtcaaaa agacatatat aatttatata
    11101 acattagtta tatattataa tatctcgaca atgtcttaac aatatctcga ttatatattt
    11161 taa
//
LOCUS       DAEPXW010000114        11150 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.118, whole genome shotgun sequence.
ACCESSION   DAEPXW010000114 DAEPXW010000000
VERSION     DAEPXW010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11150
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.118"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(<1..628)
                     /locus_tag="KRM55_003141"
     CDS             complement(<1..628)
                     /locus_tag="KRM55_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH1595351.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKL"
     gene            complement(700..1053)
                     /locus_tag="KRM55_003142"
     CDS             complement(700..1053)
                     /locus_tag="KRM55_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH1595352.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(1131..1334)
                     /locus_tag="KRM55_003143"
     CDS             complement(1131..1334)
                     /locus_tag="KRM55_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1595353.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            complement(1724..1954)
                     /locus_tag="KRM55_003144"
     CDS             complement(1724..1954)
                     /locus_tag="KRM55_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595354.1"
                     /translation="MKPTKEVLPFTIILLAVHSDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(1956..2363)
                     /locus_tag="KRM55_003145"
     CDS             complement(1956..2363)
                     /locus_tag="KRM55_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1595355.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRINDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKKLKELMEEH"
     gene            complement(2722..3171)
                     /locus_tag="KRM55_003146"
                     /pseudo
     CDS             complement(2722..3171)
                     /locus_tag="KRM55_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(3185..4111)
                     /locus_tag="KRM55_003147"
     CDS             complement(3185..4111)
                     /locus_tag="KRM55_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595356.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(4236..5018)
                     /locus_tag="KRM55_003148"
     CDS             complement(4236..5018)
                     /locus_tag="KRM55_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBH1595357.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLASLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(5174..5794)
                     /locus_tag="KRM55_003149"
     CDS             complement(5174..5794)
                     /locus_tag="KRM55_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1595358.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLISYENKRFSVINQREVLKNLPTT"
     gene            complement(5882..6580)
                     /locus_tag="KRM55_003150"
     CDS             complement(5882..6580)
                     /locus_tag="KRM55_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1595359.1"
                     /translation="MYKLSYVVRVSTKDLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKSSITNALASAFIGSLGGGKLFSNNMLVYYVVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKNDSESLAIDILTFLAGISSRDSD
                     KFLQKNDNWKIIME"
     gene            6681..7496
                     /locus_tag="KRM55_003151"
     CDS             6681..7496
                     /locus_tag="KRM55_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBH1595360.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            8168..8935
                     /locus_tag="KRM55_003152"
     CDS             8168..8935
                     /locus_tag="KRM55_003152"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBH1595361.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(9263..9940)
                     /locus_tag="KRM55_003153"
     CDS             complement(9263..9940)
                     /locus_tag="KRM55_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595362.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(10090..10407)
                     /locus_tag="KRM55_003154"
     CDS             complement(10090..10407)
                     /locus_tag="KRM55_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595363.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(10429..10767)
                     /locus_tag="KRM55_003155"
     CDS             complement(10429..10767)
                     /locus_tag="KRM55_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595364.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         3710 a         1745 c         1576 g         4119 t
ORIGIN      
        1 ctaatttatc aatatttcct gattgaatat gcttaatgtt tgattgaatt tttttatatg
       61 gccaatccca ccatttaatt tctaataatt ttgaaattgt atcattatta aatctctttt
      121 ttataatttt tgcaggtact cctccaacaa tagaatacgg tggaacgtca ttagtaacta
      181 ctgctcttgt tccaataatt gcaccatcac caatatttac acctgacata attatagaat
      241 cataacctat ccacacatca tttccaatta taatgttacc cttattgtcc caagcgtccg
      301 ttatatggtt gatatcgagt ttccattctt cataaaagat gggaaaagta tatgtggatt
      361 ttgatttcat tgagtgattt ccactagtca ttagaaattt tgcattacat gctattgagc
      421 aaaacttacc aattattaat ttatcattgt ttatagggta atgatacaat acattgtttt
      481 tctcaaaatc tcttgggtca ttataaaagt cattatatat tgtgtaatct ccaacttcta
      541 tattttccct tgttattaca tttttaagat atacagtttg ataatcatta cttcttggat
      601 ataccttatt tgaacttgga atagtcatat ttaaatctct cctttaatat atattatgtt
      661 tttgactatt ccactactac aatacatctc ttcacagaat cactccttgt taagaatctt
      721 cataagataa tggcgtcctt ttttagtgtt aagtcggata ttctttctta gtccattctt
      781 tttagcgtat aactgacaaa ctgtcatttt cttaccaata gtgtcaatgc tatcatcaag
      841 gtcattttgt attgcttttt ccttatccct taatgatata tcatcacgtt ttccctttgg
      901 gggtttatca gtaggtacaa gtttccaaga gtaaacaaat tgtggtttac caaatgaata
      961 tacatactta tatgcgtatc ttccatcttt tctctggctc tctccagttc ttaaaattct
     1021 atctttatta tctcgtcttt tttcagttga catgataaga agctcctctc aataaccgaa
     1081 ttgagcttga tacgtcatat gaatattata acatataagg ctcaatttca ttagataaag
     1141 tcaagtgtat caacgatttt ctcaaattgt tttctcttta tttgaatgcg attgctattc
     1201 ataatgaccc agccagaatc aaggttttca tcagcaagtt tacgtaattt tttctctcca
     1261 atacgaaagt attttgacgc ttcttcaatc gtcaaggtat atttttccca aataggtaca
     1321 tcagtattgt tcatagaatg tatcactcct ttctatgttc gtagttcaga agtagataga
     1381 tggctttggt aagctccatt ggtattttaa ccaatcccat tcttatgggc agaaccgtgt
     1441 catacaggtg tatcattata ctgtggtaca ggttacggca aaacaaccgt tccaaaggtt
     1501 attcacaaat cactatatag tagctctctt gattaaggtc atggcgtata gtatttgttg
     1561 gctatctgta tcacaaacgt atctatctac tttattcagt tgtcaaagaa cagtcggcat
     1621 tgatttgtct ataaaaaatc acaatagctt atgggctttt atagacaaat aattagtgat
     1681 tctccatgta ccaaatagct tgatacatgg agagagggcg agattaagac aaattaaatc
     1741 tcaaaatagc agtgattagt tttgttccta gcattcgctt tgtttcttct tctacatgaa
     1801 tatagggatt tccgtattca tcaaataaag ttttctgtga aagacgaatg atatagtgtt
     1861 caaaatgttt aagtattccg tttattgcat ttacatcgct atgtacagca agtaaaataa
     1921 ttgtaaaagg taatacttct ttagtaggtt tcatttcaat gttcctccat gagttctttc
     1981 aactttttta gtgcatttgt tttgtgataa tgtatggtat tttctgctaa atccatcaat
     2041 gttgctatgt cagcatttgt catgttgaga aagaatgaaa gtagaattat atcttgtttt
     2101 ctttttgtaa gttttccgat tgcttgtgcc attaatacat cttcaattcg tatgttgtag
     2161 tcgtaagaaa ccatacagat gtagttagaa tcataatcat ctaaaatact caatttactt
     2221 aattctgcaa gtgacaaaga ttcgagagat accaaataat catttatgcg tttattttcg
     2281 tcataaatat ctctagcata gttacgcaaa actgttttac agaaactgtc gaattgatgt
     2341 tcaattgtct tttcatcaac cataagattt caccctcttt ccatcgcaag gagttaaata
     2401 accttgctta ctcctatcac ggtgggaggg cgttaaatct tcgataaatt tcaaaaaaag
     2461 agaaaaaaat acacactctg cctatagggc aaaaatgtgt attctttaaa acgtatttaa
     2521 tttatattgg ttgtaagcca ccaccatatt gatgtatgga aatatgcatt ggctagcttt
     2581 tcataaaaat acaaagatgc ataagaaatt aatagagggg aaaaacttat tctgttatta
     2641 aaaagtaggt taattctaat aaatgctatt gcggttgaat taaactatat acatggcaat
     2701 caatcatgtt tctattcttt attatgaatt gtgacagtat tcttcaatct taaaaccaca
     2761 tttttccaat actttacttg accctctatt gtaggaatat acattagcat gaattttgtt
     2821 aaggttttat ttttcaaagg caattttgca tatttctttt actgcatttg ttgctatccc
     2881 tttgccccaa tagttcctag caagccagta acctaattca gcatttttat taatagaggt
     2941 atcttcttca aatgttaggc tgatacttcc aatagccctt tcttgataaa aaatagcata
     3001 gctaagttgt ttaacatctg gagttgccaa acaaaaacta ataaaatctc tagcgttttg
     3061 ctccctataa gggtggggga agttgtcacg aagattcttt gcaatttctt tatcattcgc
     3121 aaactcaact aaatcggtaa tataagcata attccactct ataagttcca tttttcttct
     3181 ccttttatga aacagctaca agaaatcttt ctaagccaat accacttatc aaacagcgtt
     3241 cttttttatt tccaagcatt tgataagtcc agtcaacaaa tccaccgtca actatttcaa
     3301 cggtttcatt tccttgtttg accgataatt tgaaattgat acctttataa taattattat
     3361 caacatcatc attatgaatt gataactcta tattaggaaa aataagtttg atagtttcaa
     3421 ccattctgtc gaaaaatccg tcattatctt tgtatccgtt tcttttgcgt agaataatag
     3481 agaaacgaac attttctatt tcacttaata tatctttata atagtttaag tgcttttcta
     3541 acaacatttt ttcacaagtg taagaccctg tatctatacc agatgaaacc atacaatata
     3601 agccaaaatg tgaatataaa cctttaccta caaaattttg tgctcttatt accctagcag
     3661 tagtagccat gtggataggt atggtattat tttcttcttt tctttttaat ttatcagcaa
     3721 taattattgc caacatattt gaggggtctg caagtgtttc tgtccctcgt agagcactta
     3781 ctacattata ttgatctacg gagccaaaaa cgctacagct acctaatgga gcagagggag
     3841 aaagcataat cgtcttgata tccatattga atgcttttct caataatttt gactccaaag
     3901 catgaatttc ttctggatct ataccgctag ggatagtaaa tctatttagt tggtatgact
     3961 ttagaatatc agttgcagtt aaagtatttg cttgtctatc aaacacttct aatagaagtg
     4021 agttcaaatc tgattttgat agagctgata acttatcaac tatattctta tccccaattt
     4081 tatttgtaat tctacttaaa atatcactca tagttatcct ccatactgtt actttcaaaa
     4141 taattataga attgttacaa caactaatct aggtcatttg accaaaaatg aaaaaacact
     4201 gaatatttac tattcaatat ttttttactt tgggtttatt tgattaaatc ttgaaaatac
     4261 tgtaatgcaa ccctttcagc ttcaaccttt cggacaatag gactttgtga taattcctct
     4321 cttaactcaa gatacaggtt gatagtagcc tgcaatgcat taacacagct tttatattca
     4381 tggttagcaa ccgtcttttc taatgcttca atatattggg gtgcgtccaa ttcaattttt
     4441 ctaactccac gaggtaattt acctaagaga agctgtatta acgaggcaag tactgattgt
     4501 cttaaaaaag ataaaaaatc aattgtttca aatagttctc tacgtccaat cttagtgcaa
     4561 gcgtaatgaa cccaaatcca aaatctatct tcaatccact gtaagtctgg agttgggaag
     4621 tatgcttctt ttttagaata aatttctgtt atgcagttgt tttcttcata gagaatagct
     4681 gaatcttcaa ccctatctag taaaccatct aaggttgtaa acttaaaatc aacatgaaga
     4741 acaggggaat catagaggga aattatcaat cgaggttctc caacatgttc gccagtaaaa
     4801 gcagaaacta atgttccaaa ctgttccaca ataagtaatc tctcttcgat aacttcttca
     4861 taggatttat catctgctac aatcagaaaa tccaaatcag aatattcatc taacgatttt
     4921 gtgatataag aaccgctaat tgcaagtcct attatcctac tatctctttt tgaaaattct
     4981 aatacgtttt gtatcatttt ctgttgtgtt ttagtcataa tataacacct ctcactgtct
     5041 tttattagct atcaatccaa cataattatg cataggagta ttatataatg aagaaataaa
     5101 aaaaaatagg tcacttgacc cgaaataaaa aagcattgaa taattattat tcaatacttt
     5161 tttgaaatta tacttatgtt gtaggaagat tctttaatac ctctcgctga ttaattacac
     5221 taaatctttt gttttcataa gaaattagat gttcttgtac acattcattt atagcacgat
     5281 taatgcttct aattggagcg tttacttcgc tagcaagctg ttttttggta agcagattta
     5341 attcacttct ataatagtgt aaggatatac acctcagaag tcgttcttta acacttaaag
     5401 atgataattc ttcaattaat tcagcattta caactaattt actagatatt tctcgaatca
     5461 gaaattttgt agcttcaaaa tctcccctta accagtttaa aaaatcatct ctatgaagtt
     5521 tatatacatt acaatctgtg aaagcgacaa tttcaacggg ttttttccca tcattaaatt
     5581 gttccatttc tccaaaaaaa ctaccacttc tataaagatg aatcgttgag atgtttcctt
     5641 tcacatttaa gatgaatgct tctgcaatac cgtcaatcat aagaattaca tattcatttt
     5701 cttgctcagc aaaaagaata gtctctttct ttttatacgt ttttttaaca agcttctttt
     5761 taatatcttc attcataaaa tcaattaaat gcatattcat ccctccttac caaatctttg
     5821 attaaattat atcatctttc aattagttag gtaagatagt aaaaatatat ttacatagaa
     5881 actattccat tattattttc cagttgtcat ttttctgcaa aaacttatca ctgtcacgac
     5941 tggagatacc agcaaggaat gttaggatat caatcgctaa actttcagaa tcatttttac
     6001 ggctcaaaat gacgtaaggg tcaagcaatc ctttgttttc atcattactg gttaaattga
     6061 caatgtttat ctcatgggct atttctggta gcgtttcttt ccatttgccg cgttctgctt
     6121 tagggtcaac tatgaccgcc tgtccgccga atagtaccac atagtaaaca agcatattgt
     6181 tactgaataa tttaccacca cccaatgaac cgataaacgc agacgctaac gcattggtaa
     6241 tagaactctt taccccttga ctagcaaggg caggttttag atagacattc tttccagtgt
     6301 ccagattgta gccaagatag atatcctcat gttcgccaag ggtttgtgtc gctccaaaac
     6361 caagtccagc caaaaaatcc gaagtgacat attgaatata atcattgatg taacgtttgc
     6421 tgacaggaat aaattcgcca tgcaatccta acatatcccc aaagggacgc acgagcttga
     6481 ttgataagtc gtcgtaaaag tctttgactt catcacaacg cctttttagc tcgtcaagat
     6541 cctttgtaga tacacggaca acatagctaa gtttatacat agattcttta cagttaaaag
     6601 tctgttttta aaaaaatgta taaattataa atcaaaatat agatactatc aatgacccac
     6661 taggtgcaaa aagcattgat atggttaaat tatcagacgc taaaagctgg gctatccgaa
     6721 tgagtgaaga tgggtgtgct tataaatcca ttgacaatta taagcgctca ctgaaagcgt
     6781 cgtttttcat ggcaattcaa gacgactgta ttagaaagaa tccatttaat tttcagttaa
     6841 gtgatgtttt ggaagataca acagaaccaa aaatcgctct aacaccagaa caggaaatgg
     6901 gcttattatc ctttatggag agcgataaga cttattgtaa atattatgat gatgttgtta
     6961 tcctcttaga aacaggacta cgcatttctg aattatgcgg tttgacttta gaattggata
     7021 tgaaaaataa agccattatg gtagaccatc aattgttgag tgatactaag attggctatt
     7081 atgtagaagt tccaaagacc acacagggta agcgagaaat tccaatgact gaaagagctt
     7141 atcaatcatt tgaacgtatc gtggaacggc gtaagaacgc taaagcagaa ccaatcattg
     7201 ttgatggtta ccagaacttc ctatttctta aacaagatgg attaccaaaa caagcaactc
     7261 attatcaaag catgttaaga gcgttagtca agaagtataa taagacccat gaggacaagc
     7321 taccaaagat tacgccacat acctttaggc atacactctg tacaaatatg gctaacaaag
     7381 gaatgagtcc taatatattg caatatatta tggggcataa aaacattact atgacgcttg
     7441 gctattatgc acatggttca tttagttctt cgagagctga aatggagcgg ttataatcct
     7501 agtagtatga ctagagttta ctacttattt actacttttg atggcattct tatacggtta
     7561 aatgccaact tatgcaaagt atcttccaaa aagaaaatgc cgatactcct tgtagataca
     7621 ggatatatcg acatttacca acttatgaaa agataatcaa atttaatata agtttttcaa
     7681 ataaaaagat accaaattct ttttcgagaa tctatataac attacttaag cttggttggg
     7741 gtataaacaa ttgagtagct acttttgtat ggtgttcaac tttagtcaaa actcttaagt
     7801 aatgcaaatg acttagattc attaatattc aatctcttca taagtagtga aattcgagtt
     7861 atttctgcat aattatacta tgatttatag attaattcta ttagcatcca gaataatatt
     7921 gtttatatga gtaaaattta aagaatattg tgaaaattat aggatgttaa aataaattta
     7981 ggtaaaaaag aagtgtttgt atattataga gtaccttttc taaaatatgt gggattgttt
     8041 taagaattag aataaaaatt atttttaaat tagtattttt ataatgtata gtatttttaa
     8101 tgtataatta aattgtgcag aaaatagaat ttaaagtcct atagaatttc tgattatgga
     8161 ggagaatatg aaaagaaaag ttcaagtaaa aaatattact attggagaag gtagacctaa
     8221 aatttgtgta ccaattattg ggaaaaataa aaaagatatt ataaaagagg ctaaagagtt
     8281 aaaagatgca tgtttggata ttatagagtg gcgagttgat ttttttgaga atgtagaaaa
     8341 tattaaagaa gttaaggaag ttctctatga attaagaagt tatatacatg atatcccttt
     8401 attattcaca tttagaagtg tagtagaagg gggagaaaaa ttaatatcaa gagattatta
     8461 tactactttg aataaagaaa tttctaatac aggtttagta gatttaatag atgtagagtt
     8521 atttatggga gatgaggtca tagatgaagt agttaatttt gctcataaaa aagaagtgaa
     8581 agtaattata tctaatcatg attttaataa aactccaaaa aaagaagaga ttgtatctcg
     8641 tttatgtaga atgcaggaat tgggcgcaga tttacctaaa atagctgtta tgccgcaaaa
     8701 tgaaaaagat gtgttagtgc tacttgaagc tacaaatgaa atgtttaaaa tttatgcaga
     8761 tagaccaata ataacaatgt caatgtcagg aatgggtgtt ataagtagat tgtgtggtga
     8821 aatatttggt tctgcattga cttttggagc tgcaaaaagt gtttcagcac cagggcaaat
     8881 atcatttaaa gagttaaatt cagtacttaa tctattacat aagagtatta attaaattaa
     8941 ttatatagaa atattagacg gtatttttga agatataaat taaatataaa aaacttttca
     9001 gatagtaaaa tttaaattgg gcaattatat ctgaaaagca actatttagt gtgtattttg
     9061 aaagtgatat agaaaacctt ataaatcaac tatggcatat ttaaaatatg ccattaaaac
     9121 ctactagaca ttagattata gatggtatac tagcatttct attatttata gatagtaagt
     9181 tttcataata actgttttat ctaaagtaga agatatattt gtattatgta tatttgtcat
     9241 tatttttttg taattatgta tattaatggt tatatatgta atataatatt atcactctat
     9301 tttttgtata ttgtacatta caacatttat atctatcatc atcaattaca gtagaatgta
     9361 tgggatactt attttcactt aaccaatatt tttgcatatt ctttgtccaa gactttggaa
     9421 acttcaatac ttttttgttt attataacat cctcatcttc aaaaatatta acttctcttt
     9481 ctatttttat ttttctgttg tatatcttat tgatagattc tttgtcgagt tttatgtccc
     9541 tatacatatc agggcaatag caacaaacat aatttctttt ttttcgacgt ttaaatttca
     9601 caactttctc tatgctaatt tctaattttt ttgtaccatc ttttataaat ttaatatctt
     9661 ctatgttctc gcttgaaaaa atttctgtca atcttaaagt atctacagtt tctctaatta
     9721 tttgcttttt ataagaagag aatccatatc caaaagaaag gtttaattta ttagggatgt
     9781 agccattttt atatttaaac atcttaattt tttccaattc agcattatct ttaaatttca
     9841 acttttcata cctaaaagtt actttgctaa aaagagtata ttctacatca atatattctt
     9901 ttgcaatctt aaatttatcg ctaccttcaa tcacaatcat agcctatctc caatcgtttt
     9961 atattaaaat aaggccatag aacatggtct aatagtactc attagcacta taagacaatg
    10021 ttaacacaaa aagacaaaaa aaggttattt atttcaaata accttttttt ttatataaaa
    10081 tataaagaat tatattttat tcttttttat gatgtctata atctgtgata tcagatttag
    10141 ttctcttgaa tttaagtctt ttaactcttc atttatatca ttttctaaat atgtttttcc
    10201 agtggaagta atatctttta taagaacatc tgcagaaata tttaatatat ttacaaattt
    10261 tatgaatgtt ttaagacttg gattcttttt accactttcg atttgagtta tataccaagg
    10321 cgatactcca accatatttg caaattcttt tgaagttaaa tttgcttttt tccgttcttc
    10381 tttaagtctt ttacctatat aattcattat tgttactatt tccctcactt atatttcttt
    10441 gtatttaatg atgcacttta ttaactctag cattgcaatt tgttcttttt cagttaattt
    10501 attaatcatt tcataacatt ctaaaggtac agagttatca acgccttctg ttgtaataat
    10561 atttgcaaat aacaattcaa gtggtatgtc taaagcagta gcaattttca ttataatatt
    10621 gatagatgta tttgtctcag ctctttcaat ctgaccaata tatgttggat gtaaacctgc
    10681 cttttctgct agaaactctt gactatatcc caattttgtt ctatagactt ttattctatc
    10741 tcctattatt tttcctatat ttgccaatta ttatccctcc actttagatt atattcatag
    10801 tttaagttgt tttatataga ctatttatac ttttttagtc taaatataga ctatatatgt
    10861 ttttatactg aaataagtgc tatttatttt tgtatagtct gtatctacaa taaacaaata
    10921 tggataaatc atatttttaa ttagagaaat attttcataa tttcatagcc atactacaat
    10981 aataaaacga attaataata tgttaattat agcatttttt attgtaatta catattagat
    11041 atgtagaata tattttgaaa attaaaaaaa ttttctattt tatatattga acaatttatg
    11101 taaatagaaa atttttcaat aagacttttg agtttaatca ttatattggt
//
LOCUS       DAEPXW010000115        10809 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.119, whole genome shotgun sequence.
ACCESSION   DAEPXW010000115 DAEPXW010000000
VERSION     DAEPXW010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10809
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.119"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            295..753
                     /locus_tag="KRM55_003156"
     CDS             295..753
                     /locus_tag="KRM55_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1595365.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHDKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            814..1089
                     /locus_tag="KRM55_003157"
     CDS             814..1089
                     /locus_tag="KRM55_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1595366.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1148..2422
                     /locus_tag="KRM55_003158"
     CDS             1148..2422
                     /locus_tag="KRM55_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH1595367.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPK
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2552..3604
                     /locus_tag="KRM55_003159"
     CDS             2552..3604
                     /locus_tag="KRM55_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1595368.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3604..4635
                     /locus_tag="KRM55_003160"
     CDS             3604..4635
                     /locus_tag="KRM55_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBH1595369.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4727..5539
                     /locus_tag="KRM55_003161"
     CDS             4727..5539
                     /locus_tag="KRM55_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH1595370.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5542..6462
                     /locus_tag="KRM55_003162"
     CDS             5542..6462
                     /locus_tag="KRM55_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH1595371.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6637..7083
                     /gene="rpiB"
                     /locus_tag="KRM55_003163"
     CDS             6637..7083
                     /gene="rpiB"
                     /locus_tag="KRM55_003163"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH1595372.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7113..7778
                     /locus_tag="KRM55_003164"
     CDS             7113..7778
                     /locus_tag="KRM55_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH1595373.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7888..9390
                     /locus_tag="KRM55_003165"
     CDS             7888..9390
                     /locus_tag="KRM55_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBH1595374.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRTYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9702..>10809)
                     /locus_tag="KRM55_003166"
     CDS             complement(9702..>10809)
                     /locus_tag="KRM55_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1595375.1"
                     /translation="IKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVV
                     QAIIQYLVLIFFMYIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKN
                     IENGNLKYKLEVIGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLK
                     TPLTSILSYVDMLKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFN
                     ITKTDIRELLIQSIVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNIL
                     KYSMPNTRVYIDMFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLG
                     LSIAQNIIELENAHMEIIIDADLFKVMLTFRKVN"
BASE COUNT         4314 a         1221 c         1977 g         3297 t
ORIGIN      
        1 ttgttaaaca taaaaaacca tttgtaaaaa acaaaaaaat catttctcta acaaaaaaaa
       61 ccacaaaaaa tataaaaaag tatggctagt taagtgatta acaagtaaaa attaaaataa
      121 aaatcaaaaa aaatttatca atgaaagtca gctaaaatcc tggaagagag cattattttt
      181 gggaaaacat tttcttttgt ttcacaaaaa aagccacttt ttggcacaca acatgcttta
      241 tataaagtca agaaaaacta aggtataaga caaaggcaat taggaggtgt aaatatggag
      301 tttataaatt ttgtaagtga taaagttata gaccttaaaa tggattgtaa aacgaaagaa
      361 gatttcttta aagaaataca tgataaagtt tttgatttag gctttgtaaa agaagaattt
      421 ggagaaaaaa tattagcaag agaaaatgta tttccaacag gtttaaattt aggtgattat
      481 ggagtagcaa taccacatac agatgcagaa tatattaaag agcaatttat atcagtctgt
      541 acttttaatg aaccagtagt atttagttct atggaagacc aagatgaaaa agtacctgta
      601 aatttggctt tcgtattagg acttaatcaa ccacacagtc aattatctgt attaacagaa
      661 ttaatgggaa ttatgcaaaa taaagagtta gttgataagt tgatgagttc tactgataaa
      721 gaagaagttt taaagacact aaagtcttta taaaaataaa aaagtactaa aaataaaaaa
      781 tataaaaata aaaattatta ggaggaaata aaaatgaaaa aaatattagt agcatgtgga
      841 gcaggaatag caacatcaac agtagtttgt gacaaggtag agagattagt taaggaaaat
      901 aatatacaag cagaagttat acaatgcaaa atagctgaat gtgcaacaaa gcaagaagga
      961 gcagatttaa tagtatcaac aactatacta ccaacaactt ataatatacc agcaataaaa
     1021 gcaacagcat atataactgg agtaaataca gcagcattag ataaaaaaat attagatgct
     1081 ttaaaataat cctatcatag atacattgaa ataatatttt ataaaacaga aaaaggagga
     1141 tttataaatg gataaattat tagcagtagt acaatacatt ttaaatatgg gaccgacagt
     1201 aatactacca ataacaattg tagtactagg aatgatattt agaattaagt ttacaaaagc
     1261 tttaaagtca ggtcttacaa ttggtatagg atttgtgggt ataaacttag ttgtaaacct
     1321 attaacatca acactagggc cagcggctca aggaatggtt gaaagattcg gacttaattt
     1381 aacagtaata gatgttggtt ggccaacaac agcatcagca acatgggctt caccagttgc
     1441 accaatatta ataccagttt gtttattagt aaacttacta ttattatact tcaataaaac
     1501 aaagatatta aacgttgata tatggaatta ttggcacttt atagtagcag gtgcagttgg
     1561 atatatagta acaggaagtt atgtttgggc tatattctgt gcaatactaa tggagttatt
     1621 agtactgttt attgcagaaa agacagcaaa aaatgttcag gagttttatg atttagaagg
     1681 tatagcatta ccaactggtt caacagcttc atttgctcca cttggatatt tagtaggtaa
     1741 atttgttgaa aaaataccag gaataaataa aatacaagca gacccagact ctatacaaaa
     1801 aagatttggt atatttggag aaccaatgat gatggggatt atactaggta taatacttgg
     1861 agcacttgcg ggatatgatg tagcaggaat attcaatgta ggtatatcaa tgggtgcagt
     1921 aatgttactt atgcctagaa tggttagaat attaatggaa ggtttaattc caatttcaga
     1981 atcaataaga gatttcttac aagcaaaata tggagacaga gaactttata taggtctgga
     2041 tgcagcagta gcaactggac atccagcagt tatatcaaca gctcttatac ttgttcctat
     2101 aactttgttc ttagcagtta tactaccagg aaacaaagtt ttaccatttg gagacttagc
     2161 gacaatacca ttttatatgg catttatagt gtgctttaga aaaggtaata tagttcaatc
     2221 agttataaca ggaacaatag taatagctat atcactttat atggctacaa actttgcaga
     2281 tgttcataca caattattac aacaagcaaa tatgatgcca aaaggaacaa caatggttac
     2341 aagtatagat acaggtggaa acttgctaaa atggggaata ttgaaattat ctcaattagt
     2401 ttcttcattt ggaatattct aatatgtagt taatagagat tactcttttt tagtaaagta
     2461 tgcgaaaatt tagcatttag cagctactaa aaaagagtaa tattttttat aaatttttaa
     2521 aaatacaaaa tacaagagga ggagatttat cgtgaaagca gcagtattac atggcacaaa
     2581 tgatatgaga tttgaagata tagaaataaa accatgtgaa agtgatgaag taaaaataaa
     2641 agttatggca gcaggaatat gtgggtcaga tcctccaaga gtattaaaac attggaaata
     2701 tccagttcca gctataccag gacatgagtt ttctggagta attgctgaag ttggtaagga
     2761 tgtaaaaaat gtaaaagttg gagatagagt agttgcaatt ccttttatac cttgtaatga
     2821 atgtgaatat tgtaaaagag gattattttc attgtgtgat gaccatggaa tgttaggagc
     2881 taaaagtttt ggagcttttg cagagtatgt aaatataaaa gctacaaatg tacttccaat
     2941 aggagatatg gactttgaag atgctgcaat gatagagcca ctagcagttg ctatgcatgg
     3001 agtacttaat ataggtgttc aagttggaga cactgtagcc gtaatgggta gtggaacaat
     3061 ggggcagttg gtaatacaag gacttaaaat agcaggggca ggaacaatta tagcagttga
     3121 tatatctgat aataaattaa gagaatcaaa ggaattaggg gctgatataa taattaatgc
     3181 taaagatatt aacccagtag aaaaaataaa agaacttact ggtggaaaag gcgttgacat
     3241 agctcttgaa tgtgcaggtt caaaaataac tcaagaacaa tgtttactta taactaaaaa
     3301 gaaaagtaag ataggatttt tagggatagc atattcagat ataactttat cagaagaagc
     3361 atttgaaaat atatttagaa aagaactaga attaaaaggt ttttggaact cttattctgc
     3421 accatttcca ggacaagaat ggactaaggg aatcaatcta gttaatgaag gaaagataaa
     3481 attaaaagaa atggtatctc atagattctc acttgaagat acttacaaag catttgaaat
     3541 gataagagat agaaaagaag aatttaacaa aatattaatt ttaccacaag gggttgaaaa
     3601 ataatgaaag cagtagttaa aactaaacca ggctatgata atgtagaagt tttagaagta
     3661 gaagaaccaa aagctacagg agacaaggtt aaaataaaag tagaatatag tggtatatgt
     3721 ggttcagaca tacattcatt taaaggtgaa tatgcaaata taaaagcccc agtaacatta
     3781 ggtcatgaat tttctggaat tgttgtagaa gtaggagaag atgttaaaaa tataaaagta
     3841 ggagatagag ttacatcaga gactactttt gcaacttgtg agaaatgtat atattgtgaa
     3901 actaaagatt ataacttatg cccaactaga aaaggtattg gtactcaagt aaatggaagt
     3961 tttgctgagt atgtattatc aagagaagaa agcatacatg tacttcctga aaatgtatct
     4021 ttattatcag cagcccttac agagccacta gcttgttgtg ttcatgcagc tcttgaaaag
     4081 actactatag aaagttctga tacagtttta ataataggac caggaccaat tggtttatta
     4141 ttagctcaag ttgttaaatc tcaaggtgct acagttataa tgtctggtgt tacaaaagat
     4201 aaggaaagat tagaaatagc taaaaatctt ggagtagata gaactgtaaa tgtaatggaa
     4261 gaaagtttgg cagatgtagt gaatgaaatg actgatggaa atggagtaaa caaaggattt
     4321 gattgttctg ggtttatgcc agcagttaac gaagccttaa gactgcttag aaaaaaaggt
     4381 actttcgtac aagttggaat ctttgctaaa aaattaaatg aaatggacca agaagcaata
     4441 atccaaagag agttacaata tataggaagc aggtctcaaa agccaagttc ttggattaca
     4501 gcattagatt taatggcaaa tgggaaagta aatacagaag ctttagttac tagaactgtt
     4561 ggtttagacg aatttaaaga aggtattaca gctttaatga acggggaaga aataaaagta
     4621 gcagtaaaat cttaaaaaaa catttgtatt attttaaaaa aaattgtaaa atctactgta
     4681 ggataaaaaa atgtaaggtc ttaaaaaata acaggaggaa gaaagtatga gcactcttag
     4741 agatcattct aataatatta gaaaaaacat aataaaaatg gttgcagaag ctaaaagcgg
     4801 acatccaggt ggttcattat caatagctga tatgttgaca gtattatatt ttgataagat
     4861 gaacgtatgt gcagaaaatc caaaaatggc tgatagagat agatttgttc tatcaaaagg
     4921 tcatgcagca ccagctttat atgctacatt agcagaaaaa ggatttttcc cagaagaaga
     4981 attaataaca ctaagaaaat ttggttctaa gttacaaggt cacccagaca tgaaaaaagt
     5041 agcaggaatc gatatgtcta ctggttctct tggtcaaggg ctatctgcag caaatggtat
     5101 ggcacttgca ggaaaattag ataacaaaga ctatacagta tatactatat taggtgatgg
     5161 agaaatccaa gaaggtcaaa tatgggaagc tgcaatgaca gcatcacatt acaaattaga
     5221 taatttaatt gcatttgttg acttaaatgg attacaaata gatggttcta atgaagaagt
     5281 aatgaatgta aatccagtag atgacaaatt caaatctttt ggatggaatg taatagtaat
     5341 aaatggacat tcttttgaag aaataggaaa tgcagttgat gaagctaaaa aagttacagg
     5401 aaaaccaact gtaataatag ctaaaacagt aaaaggtaaa ggtgtttcat ttatggaaaa
     5461 taatgctgca tggcatggaa cagctccaaa tgcagaacaa gcagagcaag cattgaaaga
     5521 tttagaagga ggtctatagg aatgggaata gcaactagag aagcttacgg acaagtgtta
     5581 aaagaacttg cagaaaataa agatatagta gtattagatg cagatttagg aaaagctaca
     5641 aaaagtatat catttaaaga agttgcccca gatagatttt ttgacatggg gatagcagaa
     5701 ggtgacatga ttggtacagc agcaggtctt gctacttgtg gaaaaatacc ttttgcgagt
     5761 acttttgcaa tatttgcagc aggaagaggc tatgagcaaa taagaaactc tgtagcatat
     5821 ccaaatttaa atgtaaaaat agcagctact catgcaggtg taacagtagg tgaagatggt
     5881 ggtagccatc aagctataga ggatatatct ctaatgagag gtataccaaa tatggttgta
     5941 ttaaatccag cagatgcttt agaagcaaga caagctattc ttgcatctat tgattataat
     6001 ggacctgttt atataagatt aggtagagct gcaactcctg atgtaaacag tgaaaattat
     6061 aaatttgaaa taggaaaagg aactgtttta agagaaggtt ctgacataac agtaatagct
     6121 acaggaataa tggtagcaaa agccttagaa gcagcagaag aacttgctaa agaaggtata
     6181 aatgtagaag ttgttaatat atctacaata aaaccattag atgaagcatt aataaaagaa
     6241 actgctaaga aaactggaaa agtagttaca gcagaggagc acagtataat aggtggttta
     6301 ggttcagctg tatgtgaagc tttagcagaa actaaagatg tagtagttag aagaattggt
     6361 gttaaagatg tatttggtca atcaggtaca ccagctgatt tattaaaaca ctatggttta
     6421 actacagaag atatagtaaa aaatataaaa gagttattat agatataaat atatctaaat
     6481 aacaaattga tttgacataa gtcaattaaa gctgtcttaa aaatagaaag aaatttctac
     6541 aatgggacag ctttattttt acaatacttt atttttatga taattataaa atagtctgaa
     6601 agtaatcaaa aaaattataa aaagaggtgc tatttaatga aaatatctat tggatgtgac
     6661 catggtggtt atgaattaaa ggaatatata aaggaaaatt taataaataa aggtatagaa
     6721 gttgaagatg tgggtacaaa ttcaaaagaa agtgtagatt ttccaatata tgcaaaaaag
     6781 gtaagtcaaa atgttcaaag taaaaaatct gatttaggca tactttgttg tggaacagga
     6841 ataggtatgt ctattgcagc aaataagttt aaaggaatca gagcagctgt tgtttctgac
     6901 tgtttttcag ctaaggcaac tagagaacac aataatacaa atgtactttg tttaggagaa
     6961 agagttattg ggaaaggatt agcaatgaga attgttgaag aatggttaaa ttcaagttat
     7021 aatggagaaa gacatgcaag aagattacaa atgattgatg atatagaaaa agaaaattta
     7081 taaatatata atttataaca agggggagcg ttatgtctat tatttgtgct tcaataatgt
     7141 gtgcagacca aatgaagtta aaagaggaat tagaagctct tgaagaagca ggtgtaaaat
     7201 tacttcattg tgatgttatg gatggaatat ttgttaaaaa cttggctatg ggaccagagt
     7261 tattaaaatc aataagtgaa aatacaacaa tacctttaga catacactta gccacagaaa
     7321 ctccagataa atatattgat atgatgtctt atataaagcc aaaatatatt tcttttcatg
     7381 tagaatcaag tacaaatgta aaagctgata tacaaaagtt aagaaattat ggtatagggc
     7441 cagtgttagc aataagccct caaacaagtg tggataaaat agaagaatat ataagtttag
     7501 ttgagggtat cttagtaatg acagtaaatc cagggtttgc aggtcaaaag tttaatcttt
     7561 ctgtattgga taagttggat aaacttacag agatactaaa agattatgat aatcctccat
     7621 ttatagaggt tgatggaaat ataaataagg atactattaa acttatgaat ggtaaaaaag
     7681 tagatatata tgttgttggt acttcagctt tatttaatga taagcctcca atttcatata
     7741 aagataaaat agaagaacta aaagaaagta taaagtaacc atgtaataaa attataatat
     7801 gtttctgttt aatagtaaaa atttaggtgg aaacaagaaa ttttataata tttaataaaa
     7861 attttggttg agtaaggaga attttttatg ggagacctat ataaactaca aaatggtact
     7921 gatattagag gaatagcgta tgaaaatgat tctaaagaag ttaacctaac tgtagaagaa
     7981 gtaaaaaaaa tagctaaagc gtttcatatt tggttaaaag aaaagactaa gaaagataaa
     8041 gtaactgttg ccataggaac tgattctagg ataacaggaa gccaatttag aagtactgtt
     8101 attgaaactt taactaatga tgattgtaat gtaattgatt gtgagattgc cacaactcca
     8161 gctatgttta tgacaactat tatggatgga tacaattctg atggggcgat tatgattaca
     8221 gcaagtcact taccttatta ctataatggt ttaaagtttt tcacagaaag tggaggttta
     8281 gaaaaaactg atataaaaga gatgttggat atagctgtta aaaatgatag tgtagactat
     8341 gaggaagtaa ataaaaaagg tgaagttata gtaaaaaatt taatagaaga ttattctaat
     8401 ttattgatag ataaaattag aaaaggtgta aattcaagta aaaattatga aaagcctttt
     8461 tctgggctta agatattggt tgatgcagga aatggggctg gtggattctt tgctgaaaaa
     8521 gttttacaca tactgggagc agatacgaca ggtagtcagt ttttgaaccc agatggtatg
     8581 ttcccaaatc atatacctaa tcccgaaaac aaagaagcaa tggaaagcat atgtaaagct
     8641 gtgttggata ataagagcga cctaggaata atctttgata cagatgtaga cagagctgct
     8701 attgtaggta aaaatggcaa accaataaat aaaaatgctc ttatagctgt tatatcatca
     8761 atagtattag aagaacatcc aaaaacagct atagtaacag attcgattac ttctgaagga
     8821 cttgctaaat ttataaatga attacaagga agacatcata gatttaaaag aggatataaa
     8881 aatgtaataa atgaagctat aagattaaat agtgaaggtg aagagtgcca tttagctata
     8941 gaaacgtctg gacatgctgc tttaaaagaa aattatttct tagatgatgg ggcatattta
     9001 atagctaaaa ttttaataaa agtagcaaag ctatccttgg aaggaaagac tatagaagaa
     9061 ttgatagaaa accttgaaga agctcaagaa gagaaagaag ttagaatagg cattaataaa
     9121 gaagatttta gaacatatgc agaggatata ttaaaagatt tagattctca tgttaagagt
     9181 attgatggat ggtctgtagc accaaataat tttgaaggca taagagttaa ttgtgatgaa
     9241 tcaaatggag atggatggtt tttacttaga atatcactac atgaaccatt attagcttta
     9301 aatattgaat caaataaaat tggcggagca gaacaaattt attctaagtt aaaacttttc
     9361 ttagaaaaat atgatttaaa aggtctttag ggtaaataga aagaatatat ttatattgaa
     9421 gaataaatgt aaatttgtac ctaagattac aaatattaca aaattgtaat cttaggtaac
     9481 agagatgtaa ctgattatgg aaacactatg tgatattata gatacagaga gatgaaatat
     9541 gtgatgaatt atagagaaat ataatttaaa atgtattaat atcacaccaa aaaggtataa
     9601 tcaaaaaata tgtaaatata aaccccaaca tttagaaaaa gacctctaag gaggtttttt
     9661 tcttgtttaa ataacttaaa atatattttt atattaatat atcaattaac ttttctaaaa
     9721 gtaagcatta ccttaaataa atcagcatct ataattattt ccatgtgtgc attttctaat
     9781 tcaattatat tttgagcaat tgataaacca agaccagagc catctgtttt tctagatata
     9841 tcaccccttc taaatctttc tattaactct tctggtttta gatttagttt atcatttgaa
     9901 atatttttaa acgttaatat tatattttct tcctttataa acatatctat atagacccta
     9961 gtgttaggca tagagtattt tagtatattg caaattagat tctcaaaaac tctccaagtt
    10021 tttttaccat ctatcatggt aaaaacagca tattcaggtg tttctattat aaaatctaaa
    10081 ctgctatttt gaattttgtc ttcaaattct acaatacttt gaattaaaag ttctcttata
    10141 tcggtttttg ttatattaaa ttctacatct ccactactta gcttagatgc ttcaaatatg
    10201 tcatctatta ataattttaa tctttgtgat tttttatcta aaatatttat atagtcattt
    10261 atagtctctc tgtcaaagtc attatttttt aacatatcaa catagcttaa tatagatgta
    10321 agtggagttt ttaagtcatg agatacgttt gtgataagct ctgccttcat cctttcattt
    10381 tttatattag catctacagc agtttcaaga ccgcctgtta tattatttat acttttggct
    10441 aaagtagata tttcatcatc tcctataact tctaatttat actttaaatt gccattttct
    10501 atatttttta tattttttga tatgttattt atgtaattaa acttaacaga taaaaagttg
    10561 tatatataaa aatgaaaaac tgtgtttaca agtgtaaata aaattactat agctattgcc
    10621 tcagcataat atatatacat aaagaatatc aaaacaagat attggataat agcttgtaca
    10681 actatagata ttaaaaatac tatagctaat tttttattta tagttttttt attatacata
    10741 ctaagtaagt ttgaaaagaa tacatatgtt atagacatat cttttagatt atagttatta
    10801 tatttaata
//
LOCUS       DAEPXW010000116        10684 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.120, whole genome shotgun sequence.
ACCESSION   DAEPXW010000116 DAEPXW010000000
VERSION     DAEPXW010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.120"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            153..1337
                     /locus_tag="KRM55_003167"
     CDS             153..1337
                     /locus_tag="KRM55_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595376.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(1714..2823)
                     /locus_tag="KRM55_003168"
     CDS             complement(1714..2823)
                     /locus_tag="KRM55_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1595377.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDISILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            3286..4479
                     /gene="nifV"
                     /locus_tag="KRM55_003169"
     CDS             3286..4479
                     /gene="nifV"
                     /locus_tag="KRM55_003169"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBH1595378.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            4504..6429
                     /locus_tag="KRM55_003170"
     CDS             4504..6429
                     /locus_tag="KRM55_003170"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBH1595379.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6451..7446
                     /locus_tag="KRM55_003171"
     CDS             6451..7446
                     /locus_tag="KRM55_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBH1595380.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            7772..8245
                     /locus_tag="KRM55_003172"
     CDS             7772..8245
                     /locus_tag="KRM55_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1595381.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            8279..8773
                     /locus_tag="KRM55_003173"
     CDS             8279..8773
                     /locus_tag="KRM55_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595382.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            8852..9391
                     /locus_tag="KRM55_003174"
     CDS             8852..9391
                     /locus_tag="KRM55_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1595383.1"
                     /translation="MKGMIYMIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSK
                     GLRTWEFIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAA
                     SYIQLQAHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEE
                     KKAYSDSDLDYKKVHFNHF"
     gene            9580..9891
                     /locus_tag="KRM55_003175"
     CDS             9580..9891
                     /locus_tag="KRM55_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1595384.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            9919..10605
                     /locus_tag="KRM55_003176"
     CDS             9919..10605
                     /locus_tag="KRM55_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1595385.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
BASE COUNT         4066 a         1174 c         1943 g         3501 t
ORIGIN      
        1 tataaaaaat atttaatgca aaggtagaaa taagttgaaa atgtaaagtc attggaaaaa
       61 tatagttgaa tttaatgagc aaaaatgtta ttgttttatc aataaagtgt taaaataaaa
      121 actttcaata tcattttagg gaggatgatt tcatgcaaaa aagtgtaaag aaagcaaaag
      181 taacgggctc tatgttagcc atttttggtg ttgcaagcgt tctttttagt tcacatgcag
      241 gaggaggatt tgctacaggg aatcaagaaa ctcagtacta tgtgcagtat ggatggacag
      301 caccacttat ggcaatttta gcaatgatta tacttactgc taccatgaga gaagttatca
      361 taatgtataa taataacaat tgtaggaatt ataaggattt attttgtgag ctttggagac
      421 catatccaaa acttgaaata atatgggaga tatattacta tctaatggtt ttaatagctg
      481 taagtgctgt tatagcaggt gcagcagcag tatttcaaag tataggagta aattattttg
      541 tagctgtatt tattattgga gttgtacttc ttgtctttac tatatttggt gctatgcttg
      601 tatctaaagc agctacagca atgacaatag ctattctagt atgtactctt actattttta
      661 ttgttggtat aaaagctaaa gtaccagaaa taactgaaat attatcaaat agaacgagtt
      721 tcacacctgg ctatatcaag ccaatactta atacttttat ttatgcaggt tttcaatcgg
      781 ttgttatacc tacacttgca ggatgttcaa gaccacttct taagaactca aaagaagcta
      841 ctaaggcaat gataatttca tttgttatga atgcaattgc attaggactt gctgtaacta
      901 tgctaatggg atggtataga gaaattattg ctgctgggca aacaacactc cctactcttt
      961 atgttgcagg tcaatctgga aatcatacta tatacataat ttataatgtt gcattattcc
     1021 tttgtttaat gtctacagga gtaactacta tatttggtct tgtaaataga tttgaagacc
     1081 ataaagcact ttctttcctt tcttcaagaa tgaaaagaag ggtatttaca gcttgtgcaa
     1141 taatggtagt gtcaatgctt atatcactta caggattaag taatattgtt aaatatggat
     1201 atggatattg tggttatctt ggtctattca ctatagtaat tccattcctt acactaggac
     1261 attataagaa taagaagttt gcaaaggaaa atccagaagc taaatggcca gcggaattaa
     1321 atgaaaatgt aaattagatg tagtagcaaa aaatattgct aaagagaata ctataaataa
     1381 gaatactata gataatatat ctgcatgttt attaagatta tttgcaaaat ctaatattaa
     1441 acaactataa acaagcaata taaaactaag aataaaagat aaaaagaggg tgtctcaaaa
     1501 tggactttta gtttataagg cactcttttt tatatgaagt caaatatatt ttcattattt
     1561 tgacaataaa agagactaat cctactttgg atagcctctt ttttctttaa tataaaatag
     1621 tataacagca aagtatagat tgatacatgt tttctgtagc tttctatata ttacagtgtt
     1681 tgtgtggcat tggtatttta agcaatctat aaattataat tctataattc ttctactaat
     1741 tttagattct atagccgtct ctatttcact taacattcgt tcatttttag ggtcaataaa
     1801 agcacatgta tagccttctt caccagctct accagttcta ccaatacggt ggatgtagtc
     1861 ttctggtgtt tctggtaaat cgtaattata tatatgactt actccagata tatcaagacc
     1921 acgagaagct acatctgtag ctattaagta ttgtatatct aaatttctaa atgatttcat
     1981 tattctttct cgttttgatt gagcaatatc actatgaagt ttttgacaat tatatcctct
     2041 tatagcaaga gcttcttcaa gattgtcaac ccttctctta gttctacaaa atattattgc
     2101 cataaaagga ttatcttcat ctagtacctt acataaggca tctaattttt ttctatctgt
     2161 agtttctact acttcttgtt ttatattgtt aagagtgatt tcttcttttt gaatagaaac
     2221 tacaacagga ttttttgtgt atctataagc taattttttt acttgagaat ttatagttgc
     2281 agaaaagcat agtgtttgct ttttgtttga agtctctttt aaaatagctt ccacttcatt
     2341 tttaaatccc ataagcaaca tttggtctgc ttcatctaaa acaaaagtct ttaacttact
     2401 aaggtctatt gtttttctat ttagatggtc taaaagccta cctggtgtag ctataatcat
     2461 atgaatattt ccttttagtt tctttatttg agaaccaata tcttttcctc catatgctgc
     2521 aagaatactt atatctttag attctttaag tttcatagct tcttctgtta tttgaatagc
     2581 taattctctt gtaggagaaa gtataagtac ttgtatatca tttatatcta atgatatatt
     2641 ttcaaatatc ggaagtaaaa aagctagtgt ttttcctgtt ccagtttgag cttctgctat
     2701 tacatctttt ccttctttta ttagtttaat actttctttt tgtataggtg taggtgttgt
     2761 tattcctgat ttttttagaa tatttattgt attttcacta atccctaagc ttttgaaatc
     2821 cattgttatc ttacctttca tgaaaaattt tcttttttat taaccaatta ataatatcat
     2881 atttgtaagt atttttagta aattttttaa ttattattta tatagcttaa aaatatatta
     2941 agatacttta aaatggaatg taacttaaat taaattttag taggaatttt ataggtttat
     3001 ttttaaaggt tttttgaaaa taaatctatt taaaaattaa attaaaatgc aagaaaaaca
     3061 taataacttt catttttaag aagttttcac aaaaaagaaa aaatatagtg caataaatga
     3121 tacaaagtaa tataatagat tacaagatat gaaaagccaa aaaaataaat tgcaaatgaa
     3181 attaaaatga ataaaaaata aaaaaataat cataagttag aggtatcaat gaaaaataag
     3241 acttaatgtt tttaaaatta aaagtatact aaggggggca ttaatatgtg cgttatatca
     3301 aaagatagag caaaggaaat aaaaatagta gatactactt taagagatgg agagcaaaca
     3361 gctggggttg tatttgcaaa tagagaaaaa ataatgattg ctgaaatgtt aagtgaccta
     3421 ggtgttgacc aaattgaagt tggtatacct actatgggtg gagatgaaaa aaatgtaata
     3481 aagcacatat gtagtagaaa tttaaaatca gatataatgg cttggaatag agcagtaata
     3541 aaagatgttg aagaatctat ttcttgtggt gttgatgcag tagctatatc aatatcagta
     3601 tctgacattc atatagaaaa taaattgaga acttctagag gctgggtttt agaaaatatg
     3661 gctaaaacag ttgaatttgc aaagaaaaat ggattatatg tttcagtaaa tggagaagat
     3721 gcttcaagag cagatataga cttcttaact gaatttataa atgttggaaa acaagcaggg
     3781 gcagatagat ttagatactg tgatacagta ggagttatga atcctttttc tataaagaat
     3841 gcaatagaaa ctctttatga aagaactaat tttgatatag aaatgcatac acataatgac
     3901 tttgggatgg caactgcaaa tgcacttgca ggaatagcag caggagcaaa ttatgttggt
     3961 gttacagtaa atggattagg tgaaagagca ggaaatgcag cattagaaga agttttaatg
     4021 gcacttaagt gtgtttataa atgtgattta aataatatag atactagaaa atttagagga
     4081 atatgtgagt atgtagcaca ggcatcagga agaatacttc ctacatggaa accagtagtt
     4141 ggggataata tgtttataca tgaatctggt atacatgcag atggagcttt aaaagaccca
     4201 cataactatg aaccatttga cccaagtgaa gtaaatcttg aaagaaaaat agtaataggt
     4261 aaacattcag gaagagctgc agttgtaaat aagttgagtg aatatgaaat gtatatttct
     4321 ccagaaaacg ctaccaagct attaaatgct ataagagcta catctataag attaaaaaga
     4381 agtttaatgg ataaagaaat tcttcaatta tattgtgata tactagcaca tgagaaaggc
     4441 acaacagaag aagaagcagt tagaggttca tatatttaag atataattgt ttaggaggaa
     4501 aatatgggag ataatatagt ttataaaata attaaaaaac atatagtaga tggagaagct
     4561 gttgctggaa gttcaattgg tataaaaata gaccaaactt taacacaaga ttctactgga
     4621 acaatgacat atcttcaact agaagctatg ggaatagata aagtaaagac taaaagaagt
     4681 gtggcatttg tagaccataa tatgttacaa caaggatttg aaaatgcaga cgaccataag
     4741 tatatacaaa cagtggcaga taaatatgga gtttatttct ctaagccagg aaatggtatt
     4801 tgtcatcaag tatttttaga aagattttca acaccaggag atacactttt aggttctgat
     4861 agccacacac ctactgctgg aggtgtgggc atgatggcta ttggagctgg tggattagat
     4921 gttgctttag ccatggcagg aggagcatac tatataaaag caccaaaagt ctgtaaggtg
     4981 aatctagttg gaaaattaaa taatatggta tcatcaaaag atataatatt agaagtgtta
     5041 agaaaacaaa ctgtaaaagg tggagtaggt aaagtttatg aatatggtgg agaaggtgtc
     5101 aaaagcctat ctgttccaca aagagctaca ataacaaata tgggggctga acttggagca
     5161 actacttcaa tcttcccaag tgatgaaaaa acactagaat tttttaagag tcaaggaaga
     5221 gaagacgcat ggatagagct aaaaccagat gcagatgcag tttatgatga agagattact
     5281 ataaacttgg atgaattaaa accattagct gcaaaacctc atagcccaga caatgtagat
     5341 gaagttgaaa atataggcaa gattaaaata gaccaagtgg caataggaag ttgtacaaat
     5401 tcttcttatg aagacttaat gaaagtagca caaatcctga aaggaaataa agtacataag
     5461 gatgtgagtt tggtaatagc accaggttca agacaagtta tggagatgat tgctagaaat
     5521 ggggctttgg cagatataat aagtgctgga gctagaatac tagaaaattc ttgtggtcca
     5581 tgtattggta tgggtcaatc tccaggtact gactctgtgt ctttaagaac tttcaataga
     5641 aatttctatg gtagaagtgg gactttgtca gcacaagtat atttagtaag tccagaagtg
     5701 gcagcagtaa gtgcaatcaa gggagtgctt acagacccaa gagaatttga tattaaattt
     5761 acaaatttag atgtaaatga atttttgata gatgatagca tgataattaa acctgctgat
     5821 gtaggaagtg atgtagaagt agttagaggg cctaatataa aacctttccc tcttaataca
     5881 gagctaagtc agtctatagg tggaaaagtt atattaaaga cagaagataa tataactact
     5941 gaccatataa tgccatcaaa tgctaagtta cttcctttta gaagtaatat accgtatctt
     6001 gcaaactatt gtttcaatac tgtagataca gaatttcctc agagagcaaa agacaataat
     6061 ggtggattta tagttggtgg agataattat ggtcaaggtt caagtagaga acatgcagct
     6121 ttagcaccat tatatctagg tgttaaaggg gtaatagtta agagctttgc aagaatccac
     6181 aaggctaact tgataaatag tggtataatt ccaatggagt tttgtgatga gaaagattat
     6241 gaaaatatat ctcttttaga taatctggag ataccaaata ttttagacaa tctaggtagt
     6301 ggaattttag aagttaagaa tacaactaaa ggaacttctt ttaaggtcaa agtagaattg
     6361 tcagcaaaag aagttgatgt attaaaagct ggtggaaaat taaactacac taaaaatcaa
     6421 gctaattaat atgaaaagag ggaatattga atgtataaag tgacacttat accaggagat
     6481 ggaataggac cagaagttgc gaaagctatg aaaaaggtag tagaagctac tggagtagaa
     6541 atagaatggg aagaagttaa tgcaggagag gcagttattg aagagtatgg tactccactt
     6601 cctgaatata ttatagatag tataaaaaag aacaaaatag ctataaaagg cccaattact
     6661 actcctgtag gtaaaggatt taggagtgta aatgtaactt taagacaggc attagatttg
     6721 tatgtcaatt taagacctat taaaagtttt aaggggataa aatcaagata tgaagatgtt
     6781 gatttagtgg ttgtaagaga aaatacagaa gatttatatg ctggaataga acataaaata
     6841 ggtgattatg cagctgaaag tataaagata ataacaagaa gtgcaagtga aagaatcgtt
     6901 gattttgcat gtaactatgt taaagataat aagagaaaaa aagttacagc tatacataag
     6961 gcaaatataa tgaaaatgtc tgatggattg tttttagatg tgtttagaga agttgcatca
     7021 aaacacggtg tagaatatga tgatttgatt gtagatgcag cagctatgaa cttagtttta
     7081 aatccagaaa attatgatgt aatggtaatg ccaaatcttt atggagatat actatcagat
     7141 ttaggtgctg ggcttgttgg aggtttaggt ataattccaa gtgcaaatat tggtaaagat
     7201 tgcgcgatat ttgaagctgt tcatggaagt gctccacaaa tagcaggtca aaataaggct
     7261 aatccaacag cacttattca atcatcagta atgatgctta gatacttagg tgaatatgaa
     7321 aatgcacaaa aaatagaaac agctttagaa aaagtatttc ttgaaggaag taaattgact
     7381 gtagatttag gtggctcagc ttctactaca gagtttgcgg atgaggtgtg taagtatatt
     7441 gtatagattt tatttaggga aaaagtaaaa tatagattga aggaaagagg ctttctcaaa
     7501 atagagataa gcctttttta ttggaatgat aaaatatatt tgattttata caaaagagag
     7561 ttcctcataa acgaaaaagt taattttggg atatccattt taattttaaa attaattgat
     7621 taatatgcaa agaaagatta aataaattta ttatttttaa ttgaactttc aaccaaaata
     7681 tggtaaaatt taaaaaagtt gaactttcaa ctaaaaatga atatattgat tatgtgaaat
     7741 tctataaaac agaaactatt tgactttagc catggtagtt tcagtggagg tgtgtttgat
     7801 taagacttta gatagtaata tattaagaga agtaggtact ttatctagag cagtaaattc
     7861 aataaatgat attaagtaca aggaattaaa gttacaaaaa ggacaattta catttttgac
     7921 aagaatctgt gaaaatcctg gtataaatct tgtggaatta tcaaatatgt taaaggtaga
     7981 caaggctaca acaaccaagg ctatacaaaa attaataaag gcaggatatg tagataaaaa
     8041 gcaggataag tttgataaaa gaggatataa tttaactcca actgataaat ctttggaagt
     8101 ttatgagttg ataattgaag aagagaatag aagtatagag atatgttttg ataattttac
     8161 agatgaagaa aaacaagtgg taactaagtt attagaaaaa atgagcaaaa acgtagaaaa
     8221 tgaatggttt aaagtaaaga gatagtaaat aaatacatta acttaaggag atatttttat
     8281 gattagaaaa gcgaatatga atgatttaga aagcattatg aaaattataa aatctacagt
     8341 ggaagaaatg aagacttata ataatacaca atgggatgaa aactatccat tagaaaaaga
     8401 ctttgtttca gatattaaga aacaagattt atatatttat gaagtggatg gagaagtagc
     8461 agggtttata tgtcttaatt atgaagagcc agaagaatat ttaggcttaa attggtcatc
     8521 taataaaaaa gcaatggtaa tacatagaat ggctgtaaat ccaaacttta gaaagacagg
     8581 aatagcatct aagttagttg attttgctga aaaattagct gtagaaaaca atgtatcata
     8641 cttaaagagc gatacatatt caataaactc aaaaatgaat ttattactta caaagtgtgg
     8701 ttttataaaa atcggagaaa tgagtttttt aggaaaggag aaatctttct actgttatga
     8761 taaaatatta taaagagcat tcataataca aggggtaaat aatagatttt cagcattagt
     8821 aagggcataa tataacctag tatatgctat tatgaaaggg atgatttata tgattggatt
     8881 tctaaagaaa agaagaagta ttagaaaata caaggatgtt gaagtagaaa aagaaaaatt
     8941 agataaaata ttaaaagctg ctcttttagc tccatcatca aaggggctta gaacatggga
     9001 atttatagtg gtagatgata aagaaaagct aattaattta tctcaatgta gaactaaagg
     9061 tggtggattt ttcttaaaaa atgcaccttt agctattgta attattgcag ataaagaaaa
     9121 aaatgatgtt tggatagagg atgcaagtat agctgcttca tacatacaac ttcaagctca
     9181 tgaactaggt ttaggttctt gttggataca agtaagaaat agaatgcatg atgataatat
     9241 agaagctgat aagtacatta gagaagaatt aaaagtacct agcaagtaca gtgtagaatg
     9301 tataatttct ataggatatc ctgatgaaga aaagaaagca tacagtgact ctgatttaga
     9361 ctataaaaag gttcatttta accactttta gtatataata tgttgtatta agacattata
     9421 tttttttcta ttgttaatat atacttaaaa ttgtaaaaat atatctgaat tttactaact
     9481 tatctagggg ttatgtacaa ggattttaaa gataaatata gaaattaatg tttataatcg
     9541 atacataact tgagtaacaa aatttaagga ggttaaagta tgggtatatt taaaacaaaa
     9601 atggatgagg actggaaagt aaactacatt aaagagttta atgaaatgag agattcttat
     9661 gagagtaaac ttcaaaaaaa acagtttgag gtagatagtt tgaaatcaga attggataga
     9721 ctaagaagct ataaaaatag ccttaagcca aaagaaaaac aaattactga tgatgatata
     9781 aataatataa agagtttaag aagagatggc ttaagctata aagaaatttc aaatcaaaca
     9841 agttggagca aagcaactgt aagtagggta ttaaatggac tttacgatta gcatatacat
     9901 ggggtgattt aaattgggat gaagtatagt tacaaaaaat gcataataga ttctatttta
     9961 ttgatgttta tagttcaaat attaaggatg attttgaatt atgtacttct aagtcaattt
    10021 gaatttactc ttgaaaattt taatattata aacttaattt cttttacatt agttggttta
    10081 tcgttaattt tatttttaaa agataattct ttgtataaca aggttagaaa tagaaaaatc
    10141 acagaagctt ttgaagaaaa taaaaacaat atacttattg aaaagtgtaa gctgatactt
    10201 tttgttgtgg ttttatcttt agcaataatt gtaacttatt gtactaaggg atatgtactt
    10261 tttaatgtaa ctatgatgac tttgtccgta ttgatagtcc caatatttga agagttattt
    10321 tttagagaat atatatggaa ctatctaagt aattttataa agtcaaagag taaaattatc
    10381 tgtataacat ctatactatc tggaatttat aatataggat acatagatgt tataagaaat
    10441 tatgtaatat tgtataacaa ttcgagctac acctttgaag ttattatttc aaaaattatg
    10501 ataggtactg tttttggtat tgtacttgga ttagttaagt ataggtttag agatgtaggg
    10561 ttttgtatat tattgaggag cttatttgct atatttatta ggtagatagt ataatcggtt
    10621 tataaggttg ttttaaattt aattttaaat caaccttatt ttatttgtgt tttataaagc
    10681 actt
//
LOCUS       DAEPXW010000117         9869 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.121, whole genome shotgun sequence.
ACCESSION   DAEPXW010000117 DAEPXW010000000
VERSION     DAEPXW010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9869
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.121"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(83..964)
                     /locus_tag="KRM55_003177"
     CDS             complement(83..964)
                     /locus_tag="KRM55_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH1595386.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNVADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKEINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(951..1703)
                     /locus_tag="KRM55_003178"
     CDS             complement(951..1703)
                     /locus_tag="KRM55_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBH1595387.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            1970..2287
                     /gene="trxA"
                     /locus_tag="KRM55_003179"
     CDS             1970..2287
                     /gene="trxA"
                     /locus_tag="KRM55_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH1595388.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            complement(2494..3768)
                     /locus_tag="KRM55_003180"
     CDS             complement(2494..3768)
                     /locus_tag="KRM55_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH1595389.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKLFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            4654..5490
                     /locus_tag="KRM55_003181"
     CDS             4654..5490
                     /locus_tag="KRM55_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1595390.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            5843..7420
                     /locus_tag="KRM55_003182"
     CDS             5843..7420
                     /locus_tag="KRM55_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1595391.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            7413..8597
                     /locus_tag="KRM55_003183"
     CDS             7413..8597
                     /locus_tag="KRM55_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1595392.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVITNNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TIVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIEKR
                     IL"
     gene            8615..9214
                     /locus_tag="KRM55_003184"
     CDS             8615..9214
                     /locus_tag="KRM55_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1595393.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            9238..9708
                     /locus_tag="KRM55_003185"
     CDS             9238..9708
                     /locus_tag="KRM55_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1595394.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
BASE COUNT         3603 a         1151 c         1596 g         3519 t
ORIGIN      
        1 tatgattatt aaataaaaat aacaaataaa aatactagct ttagttagct agtattttta
       61 tttgttttta ttaggtatgg gattaataca taatttcacc acttaaaaca gtataagcac
      121 ttcctccaat ttttacagaa gttatgtcat tgttttctct agttatattt acatatacct
      181 ttccaggtct gtttataaag ttaccttgct caccaataaa actagtttta tctaaaatat
      241 tgtgatgtac tatataagat gatacgcaag cgttcccagt tccacataca gggtcttctg
      301 taactccaac atatggtgct atagatctta aatggtagtc acacttttta tctatagttt
      361 ctatacaaaa tggagttata ccaattatat tattatcacc actaaatttt ttgattttat
      421 ttaaatctgg agagatattt tttaaatcat ctaaagattt tagaccaaat acaagccacc
      481 aaagtccagt atttaccttt ataataggat attcaagaag tctatcttca tgcacaccta
      541 tcatttgtgc aagttctttt ctgcaattat ctaaattttc aaattcaggt gtattctgtt
      601 ccatcataaa tatattttca ttatttattt ccttaagctc tacagataat acaccagctt
      661 ttgtttcttg ataaaatata ctcttattag tattaagctt cccttcttcc aaaagtgcat
      721 ggaaagtacc tattgttgca tgaccacata aatcaacttc taaacctggt gtgaaaaatt
      781 gtaccttaaa atctgcaaca tttgactctg aaacaaatgc agtttctgat aaattcattt
      841 ctttagccac attctgctta atttcatcag aaatgttaga ggcatcagta acgacaccag
      901 caggatttcc accaaaaggt atagttgtaa aagcatcaac ttgtttaatt ttaattttgt
      961 tcatttttat aacctccttt tatttgttct gaaatataaa tttcatgttt tatgtattga
     1021 actccaatat ataaaatgtt agagtttttt gtccaaattg aaatggcctc actgccttct
     1081 gataagtttc ctgtcaatat ttcatcatta tctacaatca aaataattcc tttgtaaagc
     1141 attttatttt caagtgtagt tttattacct ccatgaatat gaatattatc aagacctttc
     1201 agacttttgt tttctaaaag tagtatttca atattaatat tttttttgta agcaattagg
     1261 agttcttttt ttaattcaag aatttcttca taagggcaag aaattataat ttcttgtttt
     1321 gcatttttta tcatttctat tgcttttttt aatatatttt tatctccttt tatgtttaat
     1381 acgtattcta cacttttact tttatttaat atctgtaagc tattctttag attatccata
     1441 gaattgtcaa attctttttt cttatttttt aataattcat tagggtttat tggtatgtac
     1501 ttaatagggt cagttccaac attgataatt atattattgt ttaatagctt tgttatattt
     1561 tcatagactt ttgattgtgg tacacctgat aatttactta tttcatatcc tgttaaaggg
     1621 ctttccttta ataatgatat gtatatttga gattcgtatt tagtaaatcc tatattttgt
     1681 aattcattaa ttatattatc catatagaaa ctcctttgat aaaagattag taactacata
     1741 tgtagttatt aatttgattt tataatttaa gggaaaaaat gtcaactata ttaagaaaaa
     1801 aataaaatat attagaaata tttagtctca taaatattta atcttataaa tctatttatc
     1861 ataatattaa atctattaaa aataggcggt tacaaaaaag tgcctaattg aactgttata
     1921 tagggcgtag tatattaata tcaagaagat aataaaggag atgtatatta tggtaaaaat
     1981 aataaataat aatgaattta taaatgaagt agaaaataaa gatggtttag tagttgtaga
     2041 tttctttgcg acttggtgtg gaccttgtaa gatgctatca ccaatatatg aagctttagg
     2101 aaatgagatg gttgaaaaag caaacttctt gaaggtggac atagaccaaa gtatagaatt
     2161 agctcagaaa tttgaagtat ctacagtacc aactatgcta atatttaagg atggaaaacc
     2221 tgtagataga ttaataggtt ttatgcctaa ggagaattta aaaaacaaaa ttgaatcata
     2281 tatgtaatta aagtaaattg aagtaattaa aataaatctc atatataaac aaaaaaactc
     2341 attgtaatga gttttttgtt tgtatagtgt aaaatagttt gtatagttac aaatgagtgt
     2401 ctaattgcta atgaaattga ctgctgatat aatttgtttt tttgtgaaaa caaaactact
     2461 ctctatttat tgataaaaaa gaatagaaaa atcttattta aaagccaaag ttttaatagc
     2521 atgtataaag ctatccacct catcaaaagt attgtacatt cctaagctta tcctaacaag
     2581 acctacagga ttttccctca taaatctgac gtatgcctct tttggattta tacctaataa
     2641 tttttgtaca taaatatctg cacctactac tccagctcca gtttctattc caaagttatc
     2701 aactaaatat tttgctacat ctttgtaata catattactt atattaaaag atatatttgg
     2761 gataattaca ttatttgatt tatctccata tattattata ttaggtattt tactcatttc
     2821 ttctttagca tataaaaata attctctttc gtattttgaa attctgttta gaccaatttt
     2881 atttaaagtg ttcagtgctt ttcccattgc aagagttcca aaatactctg ggtatcctgc
     2941 ttcaaaacgt tggggtacgt ttgcatatag tattttgtta tcatttacaa atttggtaga
     3001 acctgagcca tatagtacag gattaaattt ttcaaagaat tttttaggtc ctaccagagc
     3061 tcctccattt agtggagaat aacatttatg agcactaaaa acaacaaaat ctatatgctc
     3121 atcacattca tgtggcatca ttgaaaaagg tttatgctga attacttgca caatatccac
     3181 caatatcttt gcaccatact tatgagctat tcttgctatt tcatatatag gagtggttat
     3241 acctgtgaca ttactagctc ctgtaactgt aacgagagat acattaccag cataattttt
     3301 aagtatattc tctaattgac ataaatcaag ttctcctttt tctgtaattc caacaacttt
     3361 tgtaggaaaa ttaactttaa aaggcaggta attagccata tgctccattg ctgtggtaat
     3421 aacaaattta tctggatttt catctttaaa aagttttgct aagaagttta ttccttctgt
     3481 agcatttttg acataaataa cagaatcctt ttcttcgtct ccatcaataa gtttgaggat
     3541 agtagagcgt acattttcat attttaaagt atttttttct gagattattc ctggagcatt
     3601 aatataagta agccaaggaa tctcacagtt taagttatcc actacgtttt ttaaaactaa
     3661 tggagtggca gagttgttaa aatatattct tttaacagtt tcaccatttt tagttttaac
     3721 tttaaggttt gcaccttcaa tgtatttaga tacatccatg aattgcataa aaaaacccct
     3781 tatctaataa actattctgt tttttattaa aaaagctcaa gttttaatca agagcttgtt
     3841 taatatatgt tatgttttta taaggggttt tgttaattaa ttcttgttga gatgtttatt
     3901 aaattacacg aaaatgagct acagttgggg gaaactgtag ctcacttgat tttgggggag
     3961 ataggttgaa cttattgttt atccgtatca tatttttagt atagtcactt attttaattt
     4021 atatacattt ttttataaat tttacataaa atgttaaaca ctaattagaa ataattatga
     4081 atatgactaa taaagttgta aaaatagtaa agaaattgat tagaacataa tggaaaatat
     4141 attgtatata attagaaaaa aagattttat atgttataaa agatgtgcaa gtataataat
     4201 tttataaaaa atacaaaata taatacaaat aattttataa aaaaaattat aaaaaaattt
     4261 aatttaattt atataaatta aaaattatat taccaatgta tatatttgag aaaagattag
     4321 tacaaagcta taatctgaat ttcaataaat atatatataa ttaagttgaa atacttgaaa
     4381 atactggaaa aaattgaaaa tagtttttgt aatataaaat gtcgattgat tttaaataat
     4441 taaatataca taagaaataa ttaaatatat ttcaatgaaa atatgataaa atatgacaaa
     4501 ttaattgatg acaataaaaa atattttgtt attgtagtat tatagggtaa attgcaaaat
     4561 atatacgaaa gtaaaatttt aaatattgac attaaattaa atatactata ctatgtaagt
     4621 gtgatgagag aattttttta gaggggattt atagtgaata taaaaaagat atttaataac
     4681 aatgtagtag taagctccct agaagatggc acagaaataa ttgtcactgg tgctggagta
     4741 ggatttaaga aaaaagtagg cgatttgata gatgaaaatt tgatttctaa gaaatatttt
     4801 gttcaagacg atcaaaggga caaatacaat caaatactta ataagacctc tattgaatac
     4861 tttaaaattt cagaagaaat tatagaaaag gctaatgaag ttttaaatac tcaagtgaat
     4921 gattcaataa tattagcttt aactagtcac atagaatttg ctgtccaaag agaaaaacaa
     4981 ggtataaaat taccaaactt aatattgaat gagacaaaac aactttatag ggaagaattt
     5041 gaatttggat tatgggcaat tgatgaaatt gaaaaaagga taggaataaa attgcctgaa
     5101 gatgaagcag gatatattgc tattcacata atcaatggtt tggaaaattc tcaaaaagat
     5161 gaaggtatta atatactaga gttttcaaaa caagttattc agataattga agaagtacat
     5221 ggatttaaat tggatgtaaa ttcattaaat tatactagac ttataactca cttaaagttt
     5281 tttgttcaaa ggattctccg aaaagaaact tacaatgata gtgatattga agatatgtat
     5341 aagttagtga ataaaaatta caataaacct aaagtgtgta ctgaagaaat tgcagcattg
     5401 gtattagaca gatttgaata taagattagt aaagaagaag aattatattt aatgattcac
     5461 ataaataaaa taacaaacag tggttgttag gattgtaact gataaagcag gcaaaaccta
     5521 agtcattgag cttaactatt agattaagtt ttttgattta ggttttttta ttagatacaa
     5581 tcaaaataca gacagtgact tttaggattg taactggtta agcaggcaaa acctaaatca
     5641 ttgaatttaa ctattaggtt aagttttttg atttaggttt ttttattaga tacaatcaaa
     5701 tacagacagt gacttttagg attgtaactg gttgagcagg caaaacctaa atcattaaac
     5761 ttaattatta aattaagttt tttgatttag gtttttctat aaatttgatt atgtttttag
     5821 ataaaaatag gaggggaaaa ttatgaaaaa aaataagtta ggtttatgga acttcttcca
     5881 aatgttagga aaaacgttta tgttcccaat agcactactt agtgtttctg ggatgatgct
     5941 aggacttggg gcaggtttta cagaccctaa gatgattgaa atggttccat ttttagggaa
     6001 tgaatatgtt aacttagttt taaacttcat gttaacaata ggattatttg catttaacaa
     6061 cttgggagca ttatttgcaa tggcaattcc actaggatta ttaaaaaaag aaaaagagtt
     6121 tggtgctttt tcaggattag taggatttat agcaatgcac ataggtacaa atttttattt
     6181 aacaagagct gatttgttag taccagcaga acagatgtca actaatggtc aagctatgat
     6241 tatgggtata caaacatata atacaagtgt tttaggtggt attgtagcag gattaattgt
     6301 ttatgcaata tatgataaag ttagtaattt aaagatacca gaatcattag gattctacag
     6361 tggaccaaga ttagttccaa ttgttagttt aatagttatg agtatagttg gattattaat
     6421 acctattgtt tggccaccat ttttcaatgc attccaaagt ttaggaagat ggatttcttc
     6481 agcaggacca ttaggatatt tttcatatgc agtggcagaa agagttacaa ttccatttgg
     6541 actaaatcat cttgtaacat ccgtattccg ttttacacca ataggtggaa ctgctgttat
     6601 tgatggagaa acgtactttg gtacattgaa catgtttatg gcatatgtag aaaataatca
     6661 gattatacct cttgatttag ctggtaaaat ggaacaaggt aaattgatga ttcaatatgg
     6721 attagctggt gctgcattgg ctatctaccg tacagcaaaa ccagaaaata gaaaggcact
     6781 taaaggactt ttaatatcag gagtgttgac agttattata ggtggtataa gtgaaccaat
     6841 agagtttcta ttcttattca tatcaccagc attatttgct ttccatacat ttatgaatgg
     6901 tctagcaaac atggtacttc catacttagg cgtgttgatg ggattcacag gagatttaat
     6961 tgcatttata agttttggtg tgttaagagg aacagctaca ggatggccaa tagcagtatt
     7021 agtagcagtt ttatattttg caatatacta ttttgtattt aagtgggcaa ttattaagtt
     7081 taatataaag accccaggac gtgaggataa agaaataaaa gtatctgaag gaaatggttc
     7141 agatttcaaa aatttgtcta catataaagg acaacaaatg atatctgctt taggtggtca
     7201 atctaatata ttatcactag ataattgtgt aactagattg cgtttaaaac tacaagatgt
     7261 atcattaata aatgaggatg caattaaaga ggctggtggt atagcagttg ttaaattgga
     7321 tgagcataca atacaagtaa ttataggaac tcaagtgtat tctttaagaa agcagatgga
     7381 taaagctatg gaaggtcatt tggaggcatg taatgattaa ttttgataaa aaagtagacc
     7441 gattgggtac atattgtacc cagtgggact atgtagaaga tagatttggt aagaaggatt
     7501 tgcttccttt tacaatttca gatatggatt tagagtttcc atttgaaata acagaggtgt
     7561 tgcaggaaag gttaaatcat agagttttgg gatacagtag atggaaacat gatgatttta
     7621 gaaattcagt tacgaattgg tatattaaaa gatttaattg tagcgttgat agtaactgga
     7681 tatattatag tccaagtgta atgtattcaa ttagcaaact tattgagatg ttaagtaatg
     7741 aaggagatgg aatccttata aatactcctg catacaatgc tttttatgat gtgataacaa
     7801 ataacaatcg taatattata aagtcacatc ttgtaaatag gaatggattc tattcaattg
     7861 attttaatga ttttgagaaa aagtgtaaaa aatctaagat atttatttta tgtaatcctc
     7921 acaatccaac tggtagagta tggagtgagt tagaacttgt taagatgata ggaatttgta
     7981 agaataatga tgtcaagata atatcagatg atatacacat ggatattgta tatgacaata
     8041 gaatgacacc tatcttaaat gttgcaaagg attatttaga ttctgtattc atttgtacat
     8101 cagcgtctaa atctttcaat ataccagcat tgactgggtc atatgtgatt ataccaaatg
     8161 aaggtattag aaataaattt gaaaatatca ctagataccg tgattttgta aattcgccag
     8221 caattctagc aatattagct acaatagtct gttatgatga ctgcgaatat tggttagatg
     8281 aactattaaa ataccttaaa gagaatctta aatatacgat tgattatata aaagataatt
     8341 tagaaccatt gaaattggtc atgccagaag gctgttactt tgcttggata gatttttccg
     8401 aacttaaaat aagtggtgag aaattccaaa aattattgat ggatattgga gaagttgcta
     8461 ttatgtcggg gtctgtatat ggtgaagaag gtgagtttta tttaaggtta aatgtggcat
     8521 gttcaagaga aaaacttgaa gatggtttaa ataggattaa aaaaactatg gattatattg
     8581 aaaaaagaat tttatagtag gaagggagat agttatggga tatttaaaaa caatggttga
     8641 tgttatgact actgaaatga atgccataag atgtttaata gatgaagcag gaatagaata
     8701 tgaaagtata gttagtgaaa ttgcaaattg tgaaggcaaa gtaattttta tgggtgtagg
     8761 aaaatctgca catataggta agaaattggc agctacattt gctagtactg gtacacctag
     8821 cttttttgta catgcaacag aggcagtgca tggagattta ggaatgattg aaagtaagga
     8881 tattacaatt ttaatatcaa atagtggaaa ttctatggaa gtggtaaact gtataaaata
     8941 tattaaagca ataggttcta agacaattgc atttacttca aacagaaatt cagtactggc
     9001 aaaagagtgt gattatgctt taatatatcc tgcaaaggat gaagcagacc atttaaatct
     9061 agcaccaaca acatcatcta caattacttt ggttttagga gattctattg catgtgcatt
     9121 atctaagagt agtaattttg gttcttcaga tttttataag taccatccag gaggaagttt
     9181 aggtgagaag ttaaaaacag ctaacaatgg ataaaagcaa aaaggagagt agtttttatg
     9241 ttcaaaatgt ttaaaaaaaa atcaataaaa tcacccatat caggaaaagt aatagagtta
     9301 tctaaaatac aagatggtgt attttctcaa aaaattatgg gagagggtgt agctatagat
     9361 tctacaggag acattgtata tgctccaatc aatggaaaga tagtagtagt agcagagact
     9421 aaacatgcat ttgtaataga attagaaaat ggaatggaac ttcttattca tgttggttta
     9481 gatactgtaa atttaaaagg cgaaggtttt gaggcattgg tgagtatggg agaacaagtg
     9541 aaggaaggaa caccaatgtt gaaaattaac cgtcctttga ttgaatcaaa gggtatatca
     9601 cttattactc cagttacaat aactaatcat tcagagtaca atatgaatac atgtaatgta
     9661 ggcaatagtg ttgaaggtgg gaaagatact gtaattgagt ttaaataaag aactaaaata
     9721 caaggttaat atttataaat acctataaac ttatgtttta taagattgat tgtatagatt
     9781 tgttgtataa aaaagaactc tttaattata aattaaggag ttctttttta ttttgtaaat
     9841 attgtttaga tttatataga aaaacactt
//
LOCUS       DAEPXW010000118         9834 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.122, whole genome shotgun sequence.
ACCESSION   DAEPXW010000118 DAEPXW010000000
VERSION     DAEPXW010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9834
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.122"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            282..1298
                     /gene="gap"
                     /locus_tag="KRM55_003186"
     CDS             282..1298
                     /gene="gap"
                     /locus_tag="KRM55_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH1595395.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            1693..2862
                     /locus_tag="KRM55_003187"
     CDS             1693..2862
                     /locus_tag="KRM55_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595396.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYSPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            3242..7495
                     /locus_tag="KRM55_003188"
     CDS             3242..7495
                     /locus_tag="KRM55_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH1595397.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATEEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            7644..8138
                     /locus_tag="KRM55_003189"
     CDS             7644..8138
                     /locus_tag="KRM55_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH1595398.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            8254..8631
                     /locus_tag="KRM55_003190"
     CDS             8254..8631
                     /locus_tag="KRM55_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBH1595399.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            8837..9277
                     /locus_tag="KRM55_003191"
     CDS             8837..9277
                     /locus_tag="KRM55_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBH1595400.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
BASE COUNT         4011 a          990 c         1734 g         3099 t
ORIGIN      
        1 atatattatt tttaaaaata agtatagttt aaaaattcaa aaaaaagatg gcaaaatatg
       61 tcccaaggga cattgagtaa aataaatgat ttcagcttat ttacactaaa aagtacatac
      121 taaatgaggg gtaaaataaa gaaaaatgat atactaattg tcttttgata ataaaaaaac
      181 atggaatttg attatttaat caagaaaaag tattgaacaa atgatttatt tagtgtacaa
      241 taatcatgta aaaacatagt aatggaggga gacatttcat aatgaaaatt aaggtaggaa
      301 tgaacggatt tggaagaata ggaagagctg tattaagaat agctcaagaa gaattaggag
      361 ataatataga aattgtagcc ataaatgcaa gagcaacaac agaatctttg gcacatttat
      421 ttacatatga ttcatgctat ggaactttta gaggtgaagt agaggcaaag gatgaagaca
      481 ctctagtagt aaactctaaa gagataaaaa tattaagata taatgaccca gaagaattac
      541 cttggaaaga attgggggtt gatatagtaa tagaatcaac aggattattt acacaaagag
      601 aaaaggcaga aaaacatatt aaagcaggag caaaaaaagt aattataaca gctccaggaa
      661 aaaatgaaga tataactata gttatcggag ttaatgagaa agaatatgat aatgaaaagc
      721 acaatataat ttcaaatgca tcttgtacta caaattgtct agctcctttt gctaaagtat
      781 tggacgaaaa atttggtata gtaaaagggt taatgactac agtacattca tatactaacg
      841 atcaaagaat attagataaa agccataaag atttgagaag agcaagagca gcggctgaat
      901 ctataatacc taccactaca ggagcagcaa aagctgtgtc aagagtacta ccacaattag
      961 aaggaaaatt aaatggtttt tcacttagag taccaacacc aacagtttca cttgttgatt
     1021 tagtgtgcga acttaaagaa aacgttacat ctgagcaagt taactctgtg ttaaaagatg
     1081 ctgctgaagg agaattaaaa ggtgttttag gatattgtga caagccactt gtttctatag
     1141 attataaagg agattcaaga tcatctatta tagacgctct atccacaatg gttatagaag
     1201 acaatatggt taaggtagtt tcttggtatg ataatgaatg gggatattct tcaagaactg
     1261 ttgacttagt aaaatatgta gctgaaaaat taaaataata tatatttctt aaagcaaatt
     1321 ttaaaaaaat tttttaaaaa aattatataa aactaaaaaa aaagattatg aaaaatattg
     1381 aaggaaaaat tttttcataa tcttttttct ttcatgcaaa aagatacaag ttacaactta
     1441 tatttgcata ttaggtcgtt agagaagtat atatatattt agtaaggaat catacttttt
     1501 ataaaatgaa agataagatg tcgaaaactt gcataaatct gaaaaatttt tattattaaa
     1561 atactgattt ccattttaaa aatgataaaa aaatgacaaa taaagttgca aatagtaata
     1621 cttataagta taattaaaaa agagaaaagg ttttgttaaa ctttataaca aaaaaagaag
     1681 ggatgattca aaatggagaa gttaacagac aggagacagg ttaaggcagt aagcatggaa
     1741 accttcattt tcctaatatt actagtagtt ggttttgggt atgttggtag tattatggga
     1801 gcaggaatga tgttcaaagt aataatgagt acagcacatg ctttactatt ggagacagtt
     1861 ttcttaatta tggctatggc agttcttgca ggcgcattaa gcgcactact ttcagagttt
     1921 ggagtaatag cgttaattaa taaaattttc gctgtattta tgaagccttt atatggacta
     1981 cctggtgcta gtatagcagg agctataaca acttatttat cagataatcc agctattata
     2041 ccttttgcta aagataaaac attcacacag tattttaaac aataccaagt tccagcatta
     2101 tgtaacttag gaacagcctt tggtatggga cttatcttaa caacatttat gatttctcaa
     2161 ggtacagaat atgtacttcc agcattaatt ggtaatttag gtgcaattat aggtagtgtc
     2221 ataagtgtta gaataatgtt gacatttact aagaagtttt ataaatacag tccggaagaa
     2281 gataaagcaa caggaacatt agagaaaaag gatgaattta gagaaatcag agaaggaaat
     2341 gtatttcaaa gagctttaga tgcaattctt gaaggtggta aaatgggggt agatatggga
     2401 atggctataa ttcctggagt cctagtagta tgtacattgg tgatgttatt aacttttgga
     2461 ccatctacag accctgttac aggtcaagaa gtttatacag gagctgcata tgaaggaata
     2521 aaattacttc cagttattgg agataaactt ggatttatat tagaaccatt atttggattt
     2581 acatcaccag aggcaatagc attccctata acttcattgg gagctgttgg cgcagcaatg
     2641 tctctagttc cagagtttat aaagtcagga gctataactc ctaatgatat agcagtattt
     2701 acagctatgg gtatgtgttg gagtggatat ttaagtacac atattggtat gatggatgca
     2761 ttaaatgcta gacagttggc aggtaaagct attctttctc atacaatagg tggtttatgt
     2821 gcaggagcag ctgctcactt tatatttaca ctcgtaggat aaatgtaatc agctaagata
     2881 aaaaataata tacaaaaaat ggttgttgat atgtaataag aatttacata tcaacaacca
     2941 tttttttctg actaaagata atttataata cataaacatt aagtggatat tagagttaag
     3001 ttatatttat gtaaaaagta acaaaaatct gtagaaattt atgacaaaat ttagtacact
     3061 aactatatgt tcttatttaa aatttaaggt tagaattagg aattacctag tagagtaagc
     3121 tttgattaat aaaagaatca taaaataaaa atattagtca taaagattat aaataactta
     3181 cttaaaataa agccatagaa cttacaaaaa ttaaaaaagc atataaatat ggaggggtac
     3241 aatggatgaa ttatttcata taggaattga tgtaggttct acaacggtga aggttgtggt
     3301 acttaataat agtaataata tagttcataa agaatataga agacattatt ctgatgtaaa
     3361 aaaatcagtt aaagaagtac taaatggtat atatgaaaaa ttgggagata taaatactac
     3421 cattataata actggttcag gtggaattgg aatatcaaaa aaattaggtg taaaatttgt
     3481 tcaggaagtt atatctagta caaaatcaat agagtatttt catcctgaga ctgatgttgt
     3541 catagaactt gggggtgaag atgcaaagat aacatatcta agtggaggaa tagaccaaag
     3601 aatgaatgga atatgtgcag gtggcactgg agcattcata gaccagatgg catcactctt
     3661 aaagacagat gccagtggat taaatgaact tgctaaaggg tataatgtta tatatcccat
     3721 agcttcaaga tgtggtgttt ttgctaaaac agatattcaa cctcttataa atgatggagc
     3781 caatcagact gatatagcaa tgagtatttt caatgcagtt gtcgtacaaa ctgtgagtgt
     3841 cctttcttgt ggaagaaaaa tagaaggaaa tgttgcgttt ttgggtggtc cattgtactt
     3901 tttatctgaa cttagagaag catttaaaag agtattagat ttaaaagatg aaaacataat
     3961 cttcccagaa aatgcacaac tttatattgc tattggagca ggattattat cagtagatga
     4021 agataatata caactaaaat ctctaataga aaaattggat agtataaaga atattgaaga
     4081 tggagaagta aatttattag aacctttatt taaagataaa aatgagtatg aagaattttc
     4141 aagaagacat gaaaaagaaa aaataaatta tgtggacata aattcaataa aaagcaattg
     4201 ttatttagga attgatgcag gctcaactac aactaaagca gcacttattg atgaggatgg
     4261 aagacttgta tattcttatt ataatagcaa tgaaggaaat ccattaaaaa caaccattaa
     4321 agttataaat gaagtatatg atatattacc aaaaaatatt aaaatattga gttcaactgt
     4381 aactggatat ggagaaggtc ttattaaaaa agctcttaaa atcgataatg gagagataga
     4441 gactatagca cattacaaag ctgctaaatt tttcaacaaa gatgtagatt ttatacttga
     4501 tattggtggt caagatatga agtgcctaaa aataaaagat ggagtaattg ataatataat
     4561 attaaatgag gcttgttcat caggttgtgg ctcattttta gagacatttg caagttcttt
     4621 atctatgaca atagaagaat ttgcgcatga aggtatttat tctcaaaatc ctgtagattt
     4681 aggttcaaga tgtactgtat ttatgaattc tagagtaaaa caagctcaaa aagaaggtgc
     4741 aagtgttgga gatatatcag cagggctatc ttattcagta ataaaaaatg ctttatttaa
     4801 agtaataaag attagagatt taaatgagat tggtaataat attgttgtac aaggtggaac
     4861 cttttataat gatttggtgc ttagaagctt tgaaaaacta attggaaaaa atgtaattag
     4921 acctaatatt tcaggaatta tgggagcttt tggttcagca cttatagcta aagaaaaata
     4981 tgaaagtgga tacaaaacat ccttgttatc taaggaagag ttgaataata tcaagctaga
     5041 agcaagtgta actagatgta aaggttgttc aaatcattgt cttcttacaa taaataaatt
     5101 ttctgataat gaaattttta tttcaggtaa tagatgtgag aagggtgaag ctatttatgg
     5161 tgataaaaaa ataggattag aaaagaaaaa accaataaat ttatttaagt acaaatacaa
     5221 tagaattttt agatacaaac cattggaaaa agaagaagca aaaaatgggg aaatagggat
     5281 accaagagta ttaaatatgt atgaagatta tccattttgg tttacttttt tcaatgctat
     5341 gggctttaga gttgtacttt cagataggtc atcaaaacag ttatatgaaa ctggtataac
     5401 tagtattgca tctgaaacag tttgttatcc aggaaaatta gttcatggac atatagaaaa
     5461 tttaattgca aaaggtataa aaaatatatt ttatccaagt gtaacaaatg aaaataaaga
     5521 ggattcaaat gcagataatt attataattg tcctgttgta atatcatatt ctgaagtaat
     5581 aaaaaacaat gtagaaaata taagaaataa gaacataaat tatataaatc catttataag
     5641 tctaaatgat aaggaaaaat tgaagaaaag actatatgat gaattatcaa gacatttttc
     5701 tgatataaaa ataactaaag aagaagttaa tcatgcagtt gataaagcta ctgaggaaca
     5761 gaatttattt aaaatggaga tacaagcagc aggtgaaaga gcacttaaag aaataaaaga
     5821 aagaaatatg aaggggattg tgttatgtgg aagaccatat catatagacc cagaaataaa
     5881 tcatggaatg ccagagctta taaattcatt agatatggca gtgcttactg aagactctat
     5941 atgtcattta gccaatgtac aaagaccact tagagttgta gaccaatggg tatatcattc
     6001 aagattgtat aaagcagcta gttttgtaag agataaaaac tatttggaac ttgttcaact
     6061 taattcattt ggctgtggat tagatgcagt aactacagac caggttcaag aaatacttaa
     6121 tgaaaaatcg aagatatata ctattataaa gattgacgaa ggcaacaatt taggagcagc
     6181 taagataagg atgaggtcct taaaagcagc tatgtttgag agagaaagca aaaatataga
     6241 tgtaaaaaat ataaaggtaa acaggataca gtatgctaaa aataatcaga taacgaacaa
     6301 acatactata ttagcaccac aaatgtctcc aatacatttc caattccttg aaaaagctgt
     6361 taacttaagt ggttataata tagaaattct aaaagatact gatagtagtg taattgaaga
     6421 agggttaaga tatgtaaata atgatgcatg ttatccagct ataatagttg taggtcagct
     6481 aataacagca ttaaaatctg gcaaatatga tttaaataac acttctgtta ctataactca
     6541 gactggtgga ggttgtagag ctacaaatta tattggattc ttaagaaagg ctatatatga
     6601 tgctggattt aaagatgttc ctgtcattgc acttagtgta aatggaatag aagatagtgg
     6661 tataatggat aatatatcac taaaattaat caatagactc tttatgtctg ttgtttatgg
     6721 tgatttgctg atgaaagtac tatatagagt aagaccatat gaaaaagtta ctggaagtgc
     6781 aaatgctcta tatgaaaaat gggttgatat atgcaaatct tctcttgtta aagcaaaaat
     6841 ttctgtattt actagaaata taaaagatat agtaaaagaa tttgataatt tagagatact
     6901 agatatcaaa aaaccaaaag taggtttggt tggagaaata ttggtgaaat tccatccaat
     6961 tgcaaataat aatttagtag atatattaga gcgagaaggt gctgaagcag tcgtgccaga
     7021 ccttacaaat ttcttcttaa gttgtgcctt taatactata tacaaacaca ctcatttaga
     7081 aggaagtaga aagagtagaa tgataggaga ggcatttata tacataactg gaatatatca
     7141 aagagtatat aaaaaagcac ttgataagag tgagagattt tatgctccag ccaatataaa
     7201 aaatgttgct aaaagtacag aaccagtagt gtcattaggt aatcaaactg gagaaggttg
     7261 gcttttaaca ggtgaaatgg ttgaattatt aaatgaaggt gtagaaaaca ttatttgtat
     7321 gcaacctttt ggatgtttac ctaatcacat aattggtaag ggttctataa aagaattaaa
     7381 gaggttgtat aaaaatgcaa atataatacc tattgattat gacccttctg caagtgaggt
     7441 aaatcaactt aacaggataa aacttatgct ttctaaggct tttaaaaata tataagattt
     7501 atattttgat atgttaaaag ttaatgaatt taaaaatata ctctatatta agtatctata
     7561 aaaaagagtt atcctatttt ttagggtaac tctttattag ttaaaaaatt atatgtatac
     7621 tgatattaaa ggggggaagt aatatgagtt tagtatatga tgtttataaa tcaaaattag
     7681 gaaatttgta catattaagt gaagatggtt ttatagttag tatatacata ggagatgaaa
     7741 aatttaataa tttaaaaaat gaatgtatta aaaaaggaat tgatataaag agaagtaagg
     7801 aagatttaaa ggaagcaata agccagatag atgattactt taatggaaaa agaaaagtct
     7861 ttaatttaaa tattcgtatt gaagggactg aatttcaaaa atcagtttat agggaaatgt
     7921 taaaaatacc ttatggagaa acattgtgtt attcagatat agcaagaaat ataaacaatc
     7981 caaaatcagt aagagcaata ggacaagcaa gtaaaagtaa taaaattcca ataataatac
     8041 cttgtcatag agtagttggc aaaaaagata ttggtggata tatggggaat cattctgatt
     8101 tgaaagagat actattaaat ttagaaagac agagttaact tagaaagaaa tgtttttatt
     8161 gttaatattt gatataataa tagtaaaaag aagtattttt tacaaaaata ataaggaatt
     8221 tattttaatt tacaaaaatg aggggggatt ttaatgtgtg ataaagttat agcatcaaaa
     8281 tatcatgaga agggatttaa ttgtgcagaa tcagttataa aagcatataa tgaggaattt
     8341 aatacagata taccagtttg tttaggaagt ggactgggtt cagggtgtgg ggttgctagt
     8401 ttatgtggtg cagtaaatgc atcaaatata ataattggat atgtaaaagg cagaaaccac
     8461 gaagatgaaa gtactaaagc taaagtatat gctaaagatt taactacaac agtaagaaaa
     8521 gagtatggtt cagagttatg tatagaccta aaaaaagatt tagttgcttg tagagaaata
     8581 atggatttcg catatgatag tctaaaggaa actttaaaaa aagaattata agaaaataag
     8641 ctatcaaata taaattattt gatagcttat ttttatagcc gatactaaat aaatcaaata
     8701 tattttagaa ttattatttg taaataaaca gcaaataatt ttaggctttt tatttaatat
     8761 agtttttatt tatatttatt tttgaatatg ttatactttg tttaaataaa tatttgtaat
     8821 gagggagatg agaagattga agaatctcaa tttacttatt aataaattat attcaaaaaa
     8881 tcataatgaa gcatataaaa cttttttatt cttagaaaat gaaagtttaa aatcaaatat
     8941 tacatattgt ttttttgact cattcctaga aatgattgat aacgaaaact catatattcg
     9001 aacaagggga ttgttattaa tctctgcaaa tgctcagtgg gatattgata ataaaattga
     9061 aataaatata gatagtatac taagtcatat cgtagataaa aaaccttctg tatcaagaat
     9121 gtttattaaa tccataccta atattacaaa gtataaagaa aatcttatta atcgcataaa
     9181 aatggaatta agtaatgcag atataagtat ttataataat aatatgaaac cattagtaga
     9241 aaaggatata aacgatacat tatctaatat tagttaaata ttaatataga aattgaatat
     9301 tatctagtta caattattta taactaagat aataaaacaa caatggtgct aatttatatg
     9361 tataaattaa ttatgaaaaa tttatataag taaaatatat taacataaag gtaaaatttt
     9421 gtatactaaa agggaatatt tacagtttaa tggcagtttt aaaataataa attaaagctg
     9481 tcatttttat ttaaaaattt ttagaaaaag tacaatagtg ttaatgtgtg aattagataa
     9541 ggtgtatata atagtttaga tgatatgata taaaatatgt tgtaaattaa atgttttctt
     9601 tgacaatata tacacaagga tgataatatc tatatgaata aaagatagtg tgtaatttga
     9661 taatatgtaa ttataacata tgatataatt acaataaagt atgtaataat ctgtagaaat
     9721 ttcaagctag ttatctaagt tttcggataa ctaaatctaa acggaataca taatgtatta
     9781 aataaatgat gatactaaaa tgatactatt tttatagaaa tttattgagg tata
//
LOCUS       DAEPXW010000119         9722 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.123, whole genome shotgun sequence.
ACCESSION   DAEPXW010000119 DAEPXW010000000
VERSION     DAEPXW010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9722
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.123"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            376..1911
                     /locus_tag="KRM55_003192"
     CDS             376..1911
                     /locus_tag="KRM55_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1595401.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIVTIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGYILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            1927..2688
                     /locus_tag="KRM55_003193"
     CDS             1927..2688
                     /locus_tag="KRM55_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595402.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQADIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            3026..3895
                     /locus_tag="KRM55_003194"
     CDS             3026..3895
                     /locus_tag="KRM55_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1595403.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            4224..4475
                     /locus_tag="KRM55_003195"
     CDS             4224..4475
                     /locus_tag="KRM55_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBH1595404.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            4587..5366
                     /locus_tag="KRM55_003196"
     CDS             4587..5366
                     /locus_tag="KRM55_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1595405.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(5501..6151)
                     /locus_tag="KRM55_003197"
     CDS             complement(5501..6151)
                     /locus_tag="KRM55_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595406.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIAFPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(6148..6651)
                     /locus_tag="KRM55_003198"
     CDS             complement(6148..6651)
                     /locus_tag="KRM55_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1595407.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINESDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(6700..7215)
                     /locus_tag="KRM55_003199"
     CDS             complement(6700..7215)
                     /locus_tag="KRM55_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH1595408.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGNKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            7495..8019
                     /locus_tag="KRM55_003200"
     CDS             7495..8019
                     /locus_tag="KRM55_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1595409.1"
                     /translation="MHEQIDCCERKKRTIDIKGENMRELLKWVSIINRYNTNYIDRKL
                     ADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVK
                     DKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMN
                     EEAKLEAKENGRKI"
     gene            8003..9406
                     /locus_tag="KRM55_003201"
     CDS             8003..9406
                     /locus_tag="KRM55_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1595410.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
BASE COUNT         3620 a         1095 c         1637 g         3370 t
ORIGIN      
        1 aatataatgg gtatataaaa tgataattaa acttaacagt aataaataat gtgagaaata
       61 ttcaaattta attaaataaa gtgtcagaaa tgtgtttaaa ttttagcatt ttaacggttc
      121 tgaccttttt tcttattttt atggagaata tcgaggatgg agtctctaat agttactttt
      181 ttgtgtctac ttgcaagttt gattaaaaaa tggctataca cacttgtgac ttaagtcatg
      241 ggaggttcag attataatct taatatataa tttgtgaaat aatttgatga cgatttgctg
      301 atgtataaac aataaagatt aactacatta aaatttaaat cttgttaagt aaaacttata
      361 aaaggagaga gatggatgat aaatgatatt ctaaccttat tatctgaaag aagtgatttt
      421 tttataaagc tatccataga acatttgatg atttctatta tttctataat aattgcgatt
      481 gttttgggtg gtataattgg tattattgta agtgaatttc ataattcttc taaacctata
      541 ttgggaacta tcaattttct atacaccatt ccatctattt ctatgctagg atttctgata
      601 ccattttccg gaattggaaa tactactgct gttattgcac ttaccattta tgcattattg
      661 ccaatggtta gaaatacata tactggaatt actaatgtgg ataaaaatat tcttgaagca
      721 gctaggggaa tgggaagtac agattttcag atattgtata aaataaaact tccgttagcc
      781 ctacctgtta ttatgtctgg tattagaaat atggtgatta tgacaattgc attagctggt
      841 atcgcttcat ttataggtgc tggaggtcta ggtgtagcca tatatagagg aatcacgaca
      901 aataacacaa taatgacaat tactggaagt atacttattg ctctattagc tttaatattt
      961 gattttattt tagggctggt agaaaaattt tttcaacgaa aaagaaaaaa gaaaaatagg
     1021 aaaaaagttt ttgccattct aggaagcctt attcttatag taactatctt tacgtcttat
     1081 ttatttaatc cttcaaagac tcaaactatt catattgcta ctaaacctat gactgaacaa
     1141 tatattcttg gtgagatgtt ggatatttta attgaaaaaa acacaggtct aaatgtggaa
     1201 attacacaag gtgtaggagg gggaacatct aatatccagc cagctatgga gaatggagaa
     1261 tttgacattt atccagagta tacaggtaca ggctggaata tggtacttaa gaaaaatgaa
     1321 ttatatactg aaagtatgtt tagtaaacta cagtcggaat acaaaactaa acttaaaatg
     1381 caatggactg gtatgtatgg tttttctaat agctatgcat tagcagttag aaaagaagtt
     1441 gcagataaat acaatttaaa aaatataacg gacttaaaag atgtatcttc taaattgaca
     1501 tttggagctg aatatgactt ttatgagaga gaggatggat atactccatt gtgtaataca
     1561 tatggactga actttaaaga tacagttgat ttagatattg gattaaaata ccaagctatc
     1621 aatgaaggta agattgacgt aatgcctata tttacaactg atggtcagta tagtgtttca
     1681 gatgttgtag ttctaaaaga tgataaaaat ttctacccat cttatcaatg tggaaatgtt
     1741 gttcgtttgg aagtattaga ggaaaatcca gaactatcaa aggtatttaa gatggttgga
     1801 tatattttga ctgataaaga aatggctaaa atgaattatg atgtagaaaa caacaattta
     1861 gaacctagag aagttgctcg tgagtttctg aataagaaag gtcttttata aattggagga
     1921 aatataatga cacctattat acaatttaaa aatattaaaa aacaatataa tgataaaact
     1981 ataatagata atcttaattt agatatagaa aaaggagagt ttttgactgt aattggttcg
     2041 tctggttctg gtaagacaac actcttaaaa atgattaatg gtctgatttt gccagatgga
     2101 ggaaatattt tgataaacca agcagatatc aaaaacgagg acttaattaa attaagacga
     2161 agaataggat attgtgtaca gggaagtgtt ctttttcctc atatgactgt tgaagaaaat
     2221 atttcatatg taccaaatct cctaagtaaa aagaataaat tagaagtaaa aagtgctgta
     2281 aacaagtgga tggaaatagt gggattgcca aatgatatga aagtgcgtta cccatcagaa
     2341 ttgtcagggg gtcagcaaca acgtgtaggg attgcaagag ctttagcttc ttctccagaa
     2401 attttattaa tggatgaacc ttttggtgca gttgatgaga ttacacgaaa gcaattacaa
     2461 aaagagataa aagaaattca taaaaaaaca ggagttacga ttatctttat tacgcatgat
     2521 atttatgaag ctttgatttt gggaacaaag actttggtat taaatcatgg agttgttcaa
     2581 cagtatgata ctcctgagaa tattttaaat actcctgcta accaatttgt agaccagtta
     2641 ttgaatataa gaaaatctat aatagatgat gataatttaa aagaataaat ttaaatttaa
     2701 aatcaaattg ttgtgataaa aactattgat ttagagctaa cttcaagttg tatacttgaa
     2761 gtggaaaagt tagattaagg tatagaaggg catttagcag ttggctgtag acgaggtaac
     2821 tgctgaaggt gctttcaata aatggctaga acctgtatct gttgaagatt ataataaatt
     2881 gaaataagaa gctcaatata cagagtagat aggcacttca aatagaagtg tcttttgtgt
     2941 gccataaaat aaatcaaaat attagcaaag aatgtgaaaa acaaaataaa ataatatgct
     3001 atctttaaaa taggaggggt gctatatgga taacaatttg attaccattg aaaaaacttt
     3061 agattatata gaaaaacatc ttttagatga gatgttagat ttaaatgtaa tttctaaaga
     3121 gataggctat tcaaaatacc atttacatag aatgtttaca tcagttgtcg gatttagtgt
     3181 acataattat atacaaagac gtagacttac tgaagcagcg agaatgctaa tttttacaga
     3241 aaaaccaatt attgagattg ctttaatctc ggggtatgac acacaacgct ctttttcaag
     3301 agggtttaaa aaaatgttta aacgtagtcc taattttttt agaagacatc aagatttttt
     3361 accactacaa ttaaaatttg atattcataa tagaaaaaaa ttacgtggag atatggtttt
     3421 agatgttaaa aaagttaatt gtgcagatat aaatattgtt ggctattctg gtaaagtaag
     3481 aaaaggattt catattattg gaaaatgctg gagggatttg cataaaaata aagagatgat
     3541 agaaaataag gtagatttag gttttttaat tggagttagt gattatagca attttaaaga
     3601 gattgagaat actcctacat ttacatacat tgcaggtgct caagtagcta cttttggcaa
     3661 attacctaat ggaatggaaa aattcgtatt accgaaaagt aattatattg tttttacttt
     3721 tattgggaaa aatgaggata gtatgcaaaa tgttgtagaa tatatctatc aagaatggtt
     3781 ccctaattca agttgccagt ttaatgaaaa taatttatat gactttgtaa aatatggaga
     3841 aaaaactgat gagaatggtt tgagtgaaat tcagttttgg gttccaatca tttaaaagaa
     3901 ggtattatgt ataaagtaga tggatttata taggcaaagt tttacagcag tatgtattta
     3961 taaataattt atagtttgta ggaaagaaat aattttacta taagattatg ataaaataca
     4021 caatactatg acaaaatagt gttaaataat agatttaatt ttgcatagga aaagttctat
     4081 aatggtgtgt attcataaat aatttataat ctgtaggaaa gaaatagttt tactataaga
     4141 ttatgataaa atacacaata ctatgataaa atagtactaa ataatagatt taattttgca
     4201 aaggataagg tgttttaata aaaatgaatg tagaaaacga attacttaaa aacctagata
     4261 gattgcatac aacagagtta ggcgttgtaa gaattaagaa aaatctttct ttggagacaa
     4321 atgatgtagt gaactggtgt aaaactaaaa tagaatctcc aaatgccatt attaatagaa
     4381 agggaaaaaa ctggtatata agtgtatatg attgtattat aacagtaaac gctcacagtt
     4441 atacaattat tacagctcat aaagaaaaga aatgaattgc aaaatacaaa ggtcaaaagc
     4501 attttccact gtttgtagta cctatgaaga agtatataaa ataatattac ttttgaataa
     4561 taatttaaat tttggaggtt gaaaaaatga atgatactgt aaaagaaaaa ttggcagagt
     4621 cactaacttc tgatactact gatattttac cttatttgcc ttatttatta caagattttt
     4681 gggaattagg aagttcacca gaacaaatgt tacaattatt tagaaagcat atacctttta
     4741 atgaggatac aaaagttttg gatttagctt gtggaaaagg tgctgtatct gtgaagcttg
     4801 caaaagagtt gaatatacat atcaaaggta ttgatttgat acctgaattt attgattatg
     4861 ctagaagaaa ggctattgaa tataaggttg atgctttgtg tgattttgaa atgaatgatg
     4921 ctaatagttc tgtaaaaatt gagcacgatt atgattgtgt gatttttgga gctgtagggg
     4981 atattttagg taattataaa gaaactataa gtaagctatt acctacaata aaaagtaagg
     5041 ggttcatttt aattgatgat gcatatgtag tagataaatc tacaaatgaa cagcttaatt
     5101 ttgagagggt gtatcccact tacaatgagt ggtgtatatt gttcaaagaa ttaggtctga
     5161 agctaattga atgtatacca tgtttagaac ttgaaaatga tgttgaagag gaaatgaatt
     5221 ggattataac tcgtgcaaat gagctaatta aaaaatatcc ttctcaaaaa gatatgtttg
     5281 aacaatatgt tattagccaa aaaaatgaat atactgattt acagcaggac cttgttggag
     5341 caacttggat tttacaaaaa gaataagata aatattagac tagataatca atgttgtagt
     5401 gaattatacc atgtctagtg aatataaata acataaaaaa ccgtcaagat gaatagttta
     5461 ttcgtgcttg acggttttta gtatttgttg aagtaaaatt ttatttcttt agtatatcac
     5521 ttttagtcaa tccatttgat ttagcctgag tattccattg atgattcccc ataagtttat
     5581 ataggaatct agggaagtta ggtgaaataa aaatagtact tttgttggaa tcatctatat
     5641 gtatattatc actaagtata ttttttgaaa gttcttttaa tgcaattcct aaatcttttt
     5701 taggtccttt acccaaaggt acggattcta gtgaaccaaa catctcccca gctccaattc
     5761 caataccttg aacccatgta aagttgattt ttttacacca atgctctatc atttgaattg
     5821 ccaaatgatt atgttcacct tcattgaatc cacagttaac tattgcatac actggaatag
     5881 gttttttatt ttgtgttttt aaaaattttt cacatttctc taaaaaatga agtaaatgag
     5941 atggaatacc atctacataa agaggaaatg ctattattaa tctatcacaa ttaagtatgg
     6001 cattaagagc gtcaggatac ttagatgtgc tatctacttt aaatgtaaaa actttattat
     6061 cattttgaat aagttgtttt aattcagata aaaaatactg tgaattattt ttatttactt
     6121 ttggactacc atttatcatt actatattca tatggattca cctcttatat cttgtatatt
     6181 ttcatagaaa caaacagagt gttcttttat attgaaattt atagcatttc catttactaa
     6241 tttcgtagca gtttcttttt cagcttctgt aatacaatct ccatagaata tagcttttaa
     6301 atttatctgt ttatcatatc tgcttttatg acgcatcata ttatctttta ttacaaagta
     6361 tggaagaata taattaatgc ttttatcaag tacgtttttg acaaaagggc taaaccctcc
     6421 gtaacagcat ctgcttatta taataattcc atcagattca tttataagtt tacccatgtt
     6481 gctgtaataa tcttttacaa cacattcaga aggagtttta atccagcaac caaaacaacc
     6541 aatacatttg tggatttctt ttgtgtttgg aagtattttt atattgtcat caagtttggg
     6601 taataacttt tctaattctt tgtcagttaa atcatgtatt aaaagcctca taaagtccat
     6661 ctccttttat tatgtatgtt tacttctaaa aattatatct tatagatttt tcagtaaatc
     6721 tttacaccaa ttaataacaa aattataata gtcaactcca taaatcattg ttgcatacat
     6781 atatgtatat tggtcaacgc aatgattttc ttctgcatca tttttttgtt tacttaattt
     6841 atttagaagt aattctactt cagttattaa catttttaag tttgtttcaa ttatttcttt
     6901 gggtagatac ttgtaaaaga atatattaac aaggtggtct tgctttgttt tagaaaaatt
     6961 tataggtttc tttaaccatt caagaaatac ttctttacca gtattagtta tggaatatag
     7021 tttttttaat ttgttaccat ctataacttc gtgatagtgt atatatcctt ttgtttctaa
     7081 tcttttaagt gcaggataga tacttccaaa gctggcgtca aaaaagtacg aggtactttc
     7141 tgacattatt tgttttaagt cgtatccact taattctttt tccattaaaa atcctaaaat
     7201 aatgtattct aacatattac ctcctggtat caattagata tatatcgatt cgatatattt
     7261 attattacag ataataaatc ttacgtcaag atgcttttta agataagcta aaaagaatta
     7321 ggagttattg ataaatatgc aaaaaaatta atataaaagg taattaaata tcaatgaaga
     7381 tttaaaaata gttaaatcaa agtaagagtc taatatataa aatttatagt aactttatgg
     7441 tttaaatata aacttgtgtg ctattgacaa agtataaaat tagcagtaga ataattgcat
     7501 gagcaaatag attgttgcga acgcaaaaaa aggacaatag atattaaagg agagaatatg
     7561 agagagctat taaaatgggt ttccattata aatagataca atacaaatta tattgacagg
     7621 aaattggcgg atattggaat caataatagc caatattttt atgtattaca catatgtaat
     7681 aatccaggta ttacacagga cactatattt gagaaaattc ttgtgaatcc tagtaatata
     7741 acaagagctt tggcaaattt agaaaaagaa ggctttataa caagagaacc aggtgtaaag
     7801 gataaaagaa catggcattt atatcctaca gaaaaatctt taggatgtta tgatgaaata
     7861 ctaaaaataa caaatgggta tgttgaggag ttgttgagtt catttgagaa agaagagcaa
     7921 gagttgttta tgtcaatgtt aaagaaagtt gcatttttgg ctattgatat gaatgaagaa
     7981 gcaaaattgg aggcgaagga aaatggaaga aaaatataag gagccattgg aatatgaaaa
     8041 ggtttcaaag ttattaacta agtacgcaat tcctagtatt atagcaatgt tagtaagtgc
     8101 tttatataac attgttgacc aaatatttat tgggcaaggt gttggtgtat tgggcaatgc
     8161 tgctacaaat gtcacttttc cactaacaac aatatgtact gcaattgcat tattgttagg
     8221 aattggagga gcgtctaagt gttcattgga attaggtgct aaaaattcag aaaaagctac
     8281 aaaagcagca ggaaattcta tatgcttgat ggctgttttt ggaataagtt tatttatagt
     8341 agtatcaata tttttaacac cactattaaa attctttggc tctacatcag aaatactacc
     8401 ttatgcacac acatatacaa aaattacatc aattggatta ccatttctta taatgtccac
     8461 tggaatgagt aagttgatac ttgcagatgg gagaccgaaa gcttctatgt tttgtatgtt
     8521 aataggagca gttattaata caattttgaa tccattattc atttttgttt ttaatatggg
     8581 aattgctggg tctgctttag caactgttat tgggcaactt atatcttttg gaataagtgt
     8641 tcattatata aagaattttc aacatattaa attacataag aaaagtttta aattagatag
     8701 tataatttat aaacatatat ttgcgctagg ttcaagctca tgttttaatc aattagcaat
     8761 gactgtaaca cagatagtta tgaataatac attggcatat tatggggcta ggtcagttta
     8821 tggaagtgag attccacttg cttgtgtcgg tatcattatt aaagtaaata tgatttttat
     8881 atctataatt attggtatat cacaaggtat gcaaccaatt atagggtata attatggggc
     8941 tgaaaagtat aatcgtgtaa aagaagcata taagtttgca gtgggaagcg caactattat
     9001 atctgttatt gcattcttat gtttccaatt cttcccaaga caaattacgt ctatatttgg
     9061 taacggaaat gagacttatt ttatatttgc agaacattat tttagaactt tcttgttctt
     9121 aacatttata aatggtgttc aaatagtatc atcaactttc tttacatcaa ttgggaaatc
     9181 agtgttggga ctttttactt ctttgactcg tcaaatttta tttttaattc cattgatagt
     9241 aattttacca atgtttatgg gaattgatgg agtaatgttt gcaggaccaa tagcagatgc
     9301 agcagcggca atggtatgta tatactttgc agttcatgaa atgaaatcat tgactataaa
     9361 gcaaaataat ttgatgagta accataataa gattgcagag gtataagaca atatttaaga
     9421 agtatagaaa attaatttaa agaagtataa taaactaatt taggaagtat agaaaattaa
     9481 tctaaagaag tataataaac taatttagaa agtatagaaa gttaatctaa agaagtgtaa
     9541 taaactaatt taggaagtat agaaaattaa tctaaagaag tataataaac taatttagga
     9601 agtatagaaa gctaatctaa agaagtataa taaactaatt taggaagtat agaaaattaa
     9661 tttaaagaag tataataaac taatttagga agtatagaaa attaatttaa agaagtataa
     9721 ta
//
LOCUS       DAEPXW010000120         9439 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.124, whole genome shotgun sequence.
ACCESSION   DAEPXW010000120 DAEPXW010000000
VERSION     DAEPXW010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9439
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.124"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(158..811)
                     /locus_tag="KRM55_003202"
     CDS             complement(158..811)
                     /locus_tag="KRM55_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1595411.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPMEEMKKEKLL"
     gene            complement(1056..2921)
                     /locus_tag="KRM55_003203"
     CDS             complement(1056..2921)
                     /locus_tag="KRM55_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase C-terminal domain-containing
                     protein"
                     /protein_id="HBH1595412.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDKDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESSYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRILILVN
                     RSENVESISLCIESSFIEEVPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(2926..5346)
                     /locus_tag="KRM55_003204"
     CDS             complement(2926..5346)
                     /locus_tag="KRM55_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBH1595413.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYEQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRNIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5360..6802)
                     /gene="glgA"
                     /locus_tag="KRM55_003205"
     CDS             complement(5360..6802)
                     /gene="glgA"
                     /locus_tag="KRM55_003205"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBH1595414.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6831..7961)
                     /gene="glgD"
                     /locus_tag="KRM55_003206"
     CDS             complement(6831..7961)
                     /gene="glgD"
                     /locus_tag="KRM55_003206"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBH1595415.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7963..9123)
                     /locus_tag="KRM55_003207"
     CDS             complement(7963..9123)
                     /locus_tag="KRM55_003207"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBH1595416.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKVMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT         2981 a         1727 c          916 g         3815 t
ORIGIN      
        1 tctataagtt cattgattta tatatgttaa tttaaataca ttattctatc gtagtgcctt
       61 agagttttta tttgtattta aagttaaatt tattcttgtt tttcctttaa tatttaatag
      121 taaaacaaca aaattataaa aaaaataaag agaaacttta taaaagcttc tcttttttca
      181 tctcttccat aggtatcgtt ttccaatgtt ctctcaaaat tctttcaaca ttttctaaat
      241 cattctccct catagatttt actacttcaa tatgttgatt attgctgtat gtcaacattt
      301 tatataactc atcttcatta tcactagtat atgactttga cataaaatta tatcttaaag
      361 agttcaatag atttactaac acctgattat ctgatttagt tatgtatata tcgtgaaatt
      421 cattacttaa ttttaaatag ctattgtaat ttttatactt tatagagacc gccatcattt
      481 ctgttaattc ttccattttt actaggtctg attcagttaa attttgtaat gctgaagaac
      541 cggctaacgc atccaatact ccaattacgg aataggtgtc taatttctcc ttttcctgaa
      601 attcttttac tacaaatccc ttattaggta ttttttctag taaattttca cctgctaacc
      661 tagttaatgc ttctctcgct ggtgttctac taactccgat agatttacaa atctcagatt
      721 cagtaattct ctgattagct tcatattctc cattttggat tttctttgat atatagtcat
      781 atacttgagt tgtaagtgga tctaccttca taagacgttc ctccatatta agattataaa
      841 agttaaatct ccctacaact ttggtagaga gttcagtttt atcttactaa tttatataat
      901 atcacaatta tgatattttt tatacttctt tgtaatattt tgaaatacta aaattcttat
      961 gataatttat acaaaaaaag tagaaaaagt tttgataaaa caaaactctt tccacattca
     1021 ccttattttc tatttatttt tctaaaaaaa gatatttaat ttactctaaa aattctaaat
     1081 gatttagagt ctaaatctac tttcaactca ttattttcaa tttgtatagt actatttgca
     1141 tttttaagac tatactttat aggtacttcc tcaataaaac tactctctat acataatgat
     1201 atactttcca cattttcact tctatttact aaaattaata ttctatcatt attttcatta
     1261 actctaataa aagaaaatac agaatcatta ttagtatata taaattctgt atttccagaa
     1321 cttaaaagtt tattcttatt tctaattttt ataacatctc tataaaaatt aagcatatct
     1381 tcgtcttcat ttttccatgg ataagttctt ctattatctg ggtcaacacc tccacaaaga
     1441 cctgcttcat ctccataata tatatatggt actccttcaa atgtcatctg tatagctaca
     1501 gcaagcttca ctaaatctac atcatcattt aattccgttt tagctcttgt aacatcatgt
     1561 gttccaatta aatttaaatt agacctaaat gattcttttg gataattttc tttaatctgc
     1621 atatatctat tacaaagttc atatgaatta atttctcctt ttaagaaaga aaacatgtta
     1681 tttctaaaag gataacccat aacagaatct aattcttcac ctaataaata acttcttctc
     1741 tgaccatagc taatcttatt tgatgcatct tcccatactt cacctataag aattgagtca
     1801 tcatctgcct tttttaattc cttttttaac tctcttataa acttagttgg taattcgtct
     1861 gcaacatcta gcctccagcc cttaataccc atatttaccc atttatttat aacgctatca
     1921 ttgtcatata ttatataatc catatagcta tgttctaatt catttatatt tggcaatgtc
     1981 ttaacatccc accaactttt atatttttga ggaaattctt caaacatata ccatgaataa
     2041 tatgaagatt ctttagattg atatgcccct aaactattat agtttccata catattaaaa
     2101 tatttactat ctgctccagt atgactaaaa actccatcta atactattga tatacctttt
     2161 tcttttgctt tatcaataag ttctttaaat gtatcttcat ccccaaacat tgggtcaatt
     2221 tttttatagt cacctgtatc atacttatga ttactagagg cttcaaatat agggcttaga
     2281 tatagtatac ttacacctaa tttttttaaa tatccaagtt tattgattat ccctcttaaa
     2341 tttccaccat ggaaatccca tcttataaca tccccttgac tatcctttat gtacataggt
     2401 gtatcttccc aatttccata tatgaaacta ttttttttag gattatcaac cttaccacta
     2461 cgatttccat tattgaatct atctacaaat atatgataaa gtattccttc tttgtaccat
     2521 gttggtactt taaaatcttt ataaacagtg atttgatatt tattaatatc actataatta
     2581 tattcacaag aatatccatt atctctgttt tttccataaa ataaagtctt tatctgacca
     2641 tccatttcaa catcaacttt aaagtaataa aaataaacac ctgtaccatc aaacttttca
     2701 atcttaccac aaaagcactt tccaagttta tctttatcta attcttcatt taaagttatt
     2761 gttctcattt cttcttctct atttatttct agggaaatag acttgatatt gtatccctca
     2821 tttactttaa cacaaatggt caattcctca tcaaatttta aagctccaaa cggagcctta
     2881 aaatttttat cccaagagtt atattctatt acactttgca tttaatcaca cccttttaaa
     2941 ccaaatgtct tttgcatact cagaaattgt tctatcagaa gaaaaaaatc cagagttagc
     3001 tatattaact aaagacattt tattccattt ttctttatct ctatataacc tgtttatatc
     3061 tgcttgagct tgaccataat tttcaaaatc tctcaataca aaatactcat cattgtaagt
     3121 agtgagtgaa ttataaatat ttcttccttc ttcgccaaga ttaggaataa atccatttat
     3181 taaatcatct actacccttt ttatatccat attagaatga tataggtcaa gtgaagaata
     3241 tccaccatat ttattataat ttagtacttg ttctgcacta agtccaaata aaaacatatt
     3301 ttctttacca acctgttcac atatctctac atttgcgccg tcaagtgtag ccaaagttat
     3361 agcaccattc atcataaact tcatattact tgttccagat gcttccttag ttgtagttga
     3421 aatttgctca ctaacatttg ctgctggtat tattatttct gctaatgata ctccataatt
     3481 ctctaaaaat actactttta acttgtcctt tactctaaca tcattattta tagtacttgc
     3541 aacagaattt ataaatttaa ttatacattt agccaaataa tatcctggtg ctgcttttgc
     3601 gccaaatata aaagttcttg ggtcaagatt caaattagga ttatcaagta attcatgata
     3661 catatgaagt acattaaata tattcagtaa ctgtctttta tacgcatgca atctcttaac
     3721 ttgaacatca aatatcgaac ttgggtctac atttaaatcg tatttatctt ttataaactt
     3781 tgctagattt gctttattat tgtattttat atcatcaagt ctttgtaaaa cagaggaatc
     3841 atttttaaat ttttcaatat tttttaattg taatgtatct ttcttccatg aatcaccaat
     3901 taaatctgta attaaattgc taagttgagg atttgaactt ataagccatc gcctatgtgc
     3961 aattccatta gtcttattat taaatttatt tggttcatct tgatagaaat cttttaatac
     4021 ctctgtttca agaatatgag tatgaagctt agcaactcca tttacactat gacttgtgac
     4081 aatacataag tttgccatat tgatattgtc acagtctatt atactcattc tttttattct
     4141 atcctgctca tatcctttat tatttaattc ctctacatat cttctattta tttcttctat
     4201 tatcatataa attcttggta atagctcttt catcatactt acaggccatt tttccattgc
     4261 ttctgacatt atagtatgat tagtatagga cactgttttt ttagttattt cccatgcttc
     4321 atcccaagat aaattttctt catcaagcaa aattctcata agttctggta tgcataaggt
     4381 aggatgtgta tcatttatat gaattgctac cttatcgaat aaattattaa tatttaattt
     4441 gttcttttta tattttctta ttatatcttg tatccctgca cttacaaaaa agtattcttg
     4501 tttcaacctc aacaacttac ctgcatagtt tgaatcatca ggatataata cctgtgatat
     4561 ttcctcagta taatacttat gttttaaagc ctcttcatag ctaccagaat aatttagagc
     4621 atttgaggta agttcaccaa aatctctctt tggtatttca ctcttaaaca atcttaaagt
     4681 atttatacat tggttttggt atccgattat tggtatatca taaggcattg ccattacagg
     4741 aaggtagttt ttatgaatta cttttaaatg actaccttcc ttgattaatt ctacctcacc
     4801 accaaacttc accattgttg cttcatttgg tcttacagtt tcccatgcat atcgtccttc
     4861 tgtaagccag ttatcaggca cttctacctg ataaccattt acaaattttt gttcaaacag
     4921 accatattta taccttattc catatccttg accacttatg ttcaaagatg ccatagaatc
     4981 taaaaagcaa gctgctaatc taccaagtcc accatttcct aaggctgggt ctacttcagc
     5041 ttcaattaaa tcatccaagt tgattcctaa ttcagataaa ccttctctaa cttcttcttc
     5101 aatatttaaa tttaataaat tagattttaa ctgtctccct attaaaaatt ctaaactaaa
     5161 ataataaact tcttttttct tatctaactt tgtagcaacc catttttttg ctatctcatc
     5221 tttcaataga ctacataata catttaacaa ttgttcatca gtagcttcct tgatagattg
     5281 tgcatataag ctatacattt ttacttcaaa tttttgcttg aatttctttt tgcttattgt
     5341 taccaaaaaa accactcctt taatcacata tgtctctata tgtttctata tactccttag
     5401 ctgatttttt ccaactatta tctgttttca ttgcattttc aactaattta atccattttt
     5461 ctttgtcctt aaatactttg attgcatttt tcaaacagaa aaacatctca tgagcattgt
     5521 aatttttaaa actaaatcca ttgccttctc cagtaaattt attataaggt gttactgtat
     5581 ctctaagccc tccagtctct ctaactattg gtaaagaacc atatctcata gctaacattt
     5641 gacctatacc acaaggctca aataatgatg gcattaagaa catatcactt gcagcatata
     5701 tctgttgggc caatgatgca ttaaaagtaa ttctagctga tactttatct gaaaaattag
     5761 aatcgtaata gttgaacatt gattgatatt gatgttctcc agttcctaaa acgacaatct
     5821 gtaaatcttc tctcataagt tctggcatca tgtatgctat taaatcaaat cctttttgag
     5881 aaactaatct cgaaactata cctatcaacg gaatagatga atctttttta agtcccaata
     5941 tatcttgtaa tctcaattta ttttctactt ttttgtcaat tgagtctaca tcataatgaa
     6001 caaatatatc tttatctttt gcagggtcat ttaaatcata atctatacca tttaatatac
     6061 cttttaattt tcctgactct tttctaagta atccatctaa ttgttcgcca taaaaagatg
     6121 tttgtatttc atttgcataa gtaggactaa cagttataat tttatctgca aaatttatac
     6181 cagctttcat aaaatttatt gagccataat actctatatc tccattatca aagtattttt
     6241 gtggtaaatc caatatatca tataaaacat gcttatcaaa tacaccttga tattggagat
     6301 tatgtatagt atacatagtt tttatatttt tatacccctc aagggttgca tatctttctt
     6361 ttagaattaa tggtaacatc cctgtatgcc aatcatttat atgtattaca tctggataaa
     6421 aatcaattct acttatagct tctaaaactg catctgtaaa gaaagtatat ctttctgcat
     6481 catctccata tccatagata ctctttcttt catcttctct tctaaaataa aattcattat
     6541 ctataaagta aaattttaca ccatctaatt ccatttctaa aagaccacag tattgatttc
     6601 tccatccaac acgtacacta aacacagcta tttcttttag ttgatctttt aaataacttg
     6661 gtatagttga atatttgggc attattaccc ttacatctac accttctttt tttaattctt
     6721 taggcaatgc ataagaaaca tctcctaatc ctccagtttt tgcaaagggc caacactctg
     6781 ctgttacata aaaaaccttc attagtcatt cccccttcta aaaaatttat ttatatattt
     6841 gtattctttt ccactacaag aggatatttt tcatctcctc ttaattcttt cccatttgat
     6901 acactcgtat ttttatctaa tattgcatta tatagttttg catttgactt tattacacaa
     6961 ttttgcatta ctattgagtt ctctataact gttccttttt caacatttac ctttctaaat
     7021 attatactat cttttacagt accttctatt aaacaaccag atgctataaa gctattttct
     7081 actttagcac tatctgtata aattgtaggt gattcattct tttcttttgt aaatatcttt
     7141 ctttcagaat ataataattc atctgcaact tctaaattta ataaatcttt gctcatttca
     7201 aaatatgatt caacagaatt tacacatttt agatatcctg tatattcata ggctcctatt
     7261 ttcatgtttt ctgcttcttc aataataaat tcttctaaat aacaataatt gcctttattt
     7321 acaatgttat atatacattc aacaaaatct tcacgcttca taatatatgt ctccatacat
     7381 atgtttgctc tagggaactt acctaaatta tttcctacat ttattaccct attgttacta
     7441 tctaaattta gagttaagtt accagcaaaa tctttatttg cattatttac atttttatat
     7501 attatagtta tatcattatg agatttttta tggtattcca atgcttgaga ataatttaaa
     7561 ttgcatagca tatagcttgg agctattaaa atatattctt cttcactctt ttctatataa
     7621 tctagattag ctaagatagt atatatatca ccttctctat gtgagtaagt atttctatac
     7681 ttagtgtttt ctggactaaa aattgatagg ccaccttttt ttctacttaa atcccaatct
     7741 ttaccactac ctatatggtc tgttaatgat ctgtattttt cttttgcgaa tattccaact
     7801 ttagtgattc ctgaatttat catattagat aaagcaaagt ctattattct atatcttcca
     7861 gctattggtg tagatgctat tggtcttcca tagttaagtt tgtttattgc tgggtctcct
     7921 tttttgttta aatttattat ccctaaacat tcatttctca tcttaaagac ctccttctat
     7981 taatacgcat ctaggttcga tattttcata ctcagaaact acatttattt cattatttac
     8041 attctttatc tgaacattat catttatagt tgcacactca cctatcataa ctttttctat
     8101 agttacattt tcacctatta caacatttgg cattattact gaatcaatta ctttacttcc
     8161 tttaccaaca acaactccat gtgataatac agagttacct acttcaccta aaattctaca
     8221 accatcagct atcattgatc tatgaacatt tgcattttta cctatatatt gtggaggcat
     8281 tgccatagta tttgtatata tcttccactt agggtctgct aaatcaagtg tttctggaga
     8341 ttttattata tccatattag catcccatag actttgtata gttcctacat ctctccagta
     8401 tcctttaaat ggataagcat acattccaac attatcttct aacattttag gtattaaatt
     8461 ttttccaaaa tcatcataat ttatttctgg atttttttct gcttccttaa aataatttct
     8521 caacattttc caatcaaata tgtatactcc catagatgcc aaattgctct taggttcact
     8581 tggtttttct tcaaattcat agatacttga atcttcattt gtattcatta tcccaaatct
     8641 tgaagcttca tcccaaggaa cttcaatcac tgctattgta gctttagagc ctttttcctt
     8701 gtgaaatttt aacattttgc tataatccat cttgtatata tggtcaccag ataatatcaa
     8761 tacatattct ggattatagg tatctacaaa gtccatattt tgatatatcg catgtgctgt
     8821 accattatac caatttcctt ctttttcatt cataaatggt tgtaaaacat agacaccacc
     8881 atttattctg tccaaatccc aatgacttcc catgcctata tgtgaattta atatcaacgg
     8941 tctatattga gttaaaacac ctacagtatc aataccagag tttgaacaat tgcttaacac
     9001 aaaatctata attctatact tacctccaaa tgatacagct ggtttggcaa ttctttttgt
     9061 aaaaacacct aatcttgaac cttgccctcc tgccaaaatc atagctaaca tctctttttt
     9121 catttaatga cactcccctc atctagtaat taatatttat aattgcattt ttacttttat
     9181 aaactttatc agtcaataaa tgtcgtgtat aaatgttgct taaataatac cttaataaaa
     9241 ataaaataat atcaactata caattgatat aatgtatacc ccataatgga cttaccgacg
     9301 tatacattat tttccataag cactatagta tttattaata ttcaattatc ggttaaaaaa
     9361 taatacaaat tttattttat aaatataaaa acatttttta taaatccctt gtgtcatata
     9421 aacatgctta ttttttaat
//
LOCUS       DAEPXW010000121         9393 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.125, whole genome shotgun sequence.
ACCESSION   DAEPXW010000121 DAEPXW010000000
VERSION     DAEPXW010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9393
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.125"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            177..1187
                     /locus_tag="KRM55_003208"
     CDS             177..1187
                     /locus_tag="KRM55_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH1595417.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            1323..1811
                     /locus_tag="KRM55_003209"
     CDS             1323..1811
                     /locus_tag="KRM55_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1595418.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            1987..3915
                     /locus_tag="KRM55_003210"
     CDS             1987..3915
                     /locus_tag="KRM55_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1595419.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            4092..4502
                     /locus_tag="KRM55_003211"
     CDS             4092..4502
                     /locus_tag="KRM55_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBH1595420.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            4524..4826
                     /locus_tag="KRM55_003212"
     CDS             4524..4826
                     /locus_tag="KRM55_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBH1595421.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(5043..5735)
                     /locus_tag="KRM55_003213"
     CDS             complement(5043..5735)
                     /locus_tag="KRM55_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH1595422.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(5761..6948)
                     /locus_tag="KRM55_003214"
     CDS             complement(5761..6948)
                     /locus_tag="KRM55_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1595423.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            7284..9083
                     /locus_tag="KRM55_003215"
     CDS             7284..9083
                     /locus_tag="KRM55_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1595424.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNIGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVISGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFD"
BASE COUNT         3574 a         1034 c         1659 g         3126 t
ORIGIN      
        1 tataccacat attttgggta ttgtatactg gaattagagt aattaattta ttttttaaca
       61 tacaaatgat tttatgaaaa aaaacaagac tcaaaaattt ttatattctt tgatagaata
      121 aaattgagag taaatttatt gaattttata aaatttataa ggggtgagtc taagatatgc
      181 atgaagataa aaatgatata tttgaatcaa tagatactga ggattttgat aataaaacag
      241 aagaagaatg tttagagcta gtaagaaaaa atggattgaa tttaatatac ataaaaaatc
      301 aaacagaaga gatatgtcta gaggctgtta gacaaaattg taatgcaata aaatgtgttc
      361 agaatcagac agaaaaaata tgtatagaag cagttaaaca agattggaga atgttagaat
      421 ttgtggaaga gccaacagaa gaaatttgca tgttggctat taaccaagat ggaacagcat
      481 taaaatatat agaaaatcag acagaggagt tatgcttaag agccgttgaa aaaaatggtg
      541 cagctttgga gtatgtaaaa gaacaaacag aagaaatatg tatagaagca gttagaaaca
      601 gcgaatttgg attggcaaga gtgaaaaatc aaacagaaaa aatatgtatg gaagcagtta
      661 agcattgtag ctataatcta aaatgggtag aaaatcaaac agaagaaata tgtatggaag
      721 cagtgagaca aaatgggctt gatttgaaat ttgtaaaaaa tcaaacagaa acaatctgtt
      781 taagagcagt aagacaaaat ggaatggcat tagaatttgt aaaggaacag actgttggta
      841 tatgcttaaa ggcagtaaga caatatggaa tggcattaaa atttgtaaag gaacaaacag
      901 aagaaatttg tacagaagct ataaaacaag ataaaagagc acttagtttt gtaaaaggag
      961 ataaggaaaa atataaggct ctatatgata ataatgaacc atttgcaaag agatatgtta
     1021 gaaatgtaat agaaaaagaa aacagagcat tgattaaaaa aggagaagaa aatgcaaaaa
     1081 tcaaaattgc aggaaaactt tatgatagag gcatgtcttt tgaagatata tcagatatag
     1141 ttgagattga aataagcaag ttaaaagtga gtttaggtgt tttttaaagt aataaatgta
     1201 ggtgtttttt atgggaaata gttaataaaa aaataatcga ctagctcttt gtaggacagc
     1261 aaaattagtg atataatttg atgtataata aattattttt attagataag ggggaattaa
     1321 agttgaagat tacagtatta taccaaacaa gaagtggaaa cacagaaagg gtcgctaagc
     1381 tgatagaaga gggcgctaaa aaggtggatg gagtagatgt aaagcttatg agacttgata
     1441 atattgattt agattattta aatgaaagta aagcagtaat atttggaaca cctacttatt
     1501 tagcaaatac aacttgggaa gtaaaaaaat ggtttgatga agattcaaaa aaagttaatt
     1561 tagctggaaa attaggagct gtttttgcta catgtgatta tatatgtgga ggtccagatg
     1621 ttgcgatact tactatagta ggacatttga tggttaaagg gatgcttgtg tattctggag
     1681 gtggttcttt aggaaagcca tttatacatt taggacatgt acattcaatt gaaggtccag
     1741 agttacaaga tgagaaggct ataatatttg gtgaaagaat tgctactaag gcaaaagaac
     1801 tatttgctta atttctatat gcatagtaat gattagagta aatttagggt tttaatggag
     1861 atttgaagta aaagttataa aataaaaaat tttccataaa attactcaag atgaattata
     1921 atataattat aaataaatta tattattaaa atatttaaaa tcaaacgtca atagcgaggg
     1981 aagtttatgg tatggcatat agaatatgag attttttctg caattatagt tattttttta
     2041 atggtatact tttttagaag taaatttata cctactttac aaaacaaaat atattgtgca
     2101 cttttaatat tctcattttt atttataatt tcaaatattt taggttcatt ttgtctaaat
     2161 aatatagaca aaattccaat ttttattact tttttattga atcagatata cttattgtta
     2221 ttgccaatac cagcagcact tgtatcattt tatgttatgg ctattattta tcaagatata
     2281 aggtatatga aaaaaagatt attattttta tctataccac ttataatttg tataatctta
     2341 tctattacaa atccttttac gcatattcta tttggattgt caaaagaaac aggttatata
     2401 cgaggttgtg gatatgttgc aacttttgca tcttttttct tttatgcaat atattcagca
     2461 tttttatctt ttaaatatag aaaagcaatg catgaatcaa aaatatgggc tattagaggt
     2521 tttcttatag tttcaattgt ggcaattatc ttacaggcaa tttttttaca gtatcttctt
     2581 acaggaactg catgtgcatg tagtttactt ttgacatatc tttctatgca gaatcgaggt
     2641 cttattattg atgaccttac tggtgtactc aatagacaat cttttattca agagctagat
     2701 ttgaatatca atactgaaca atcaggattt attattacaa ttgcgcttga tgattttaag
     2761 tttatgaatg aaacttttgg aacaaaaaat ggagatattg cactaaaaga agttggaaaa
     2821 tatttgattc agatacatga tgtaaaccat gtatatagaa tagggggaga tatattttct
     2881 attgttgtca atagtcaatt aggtatagaa ccagatgata ttatcagaaa gatagaagaa
     2941 agatttaaaa agccttggct agtagaagag ataagtttta atttagcaac tagtattgct
     3001 gttgtttatt acccagaaaa tgcagaaacg acagaagatg taattgttgc tatagatttc
     3061 tctatacatg aagcaaaacg ctctgagtca aggcgagttg tttatgcaga tgcgtctata
     3121 agtgaaaaga taaagaagaa acatgttatt aaaaattgtt taaaagaagc attaaaaaat
     3181 gatgggtttg aagtgtacta ccaacctata ttttctaata gcaggggcag gtttacttca
     3241 gcagaggcat tacttaggct agaacacaaa gagttaggtt ttatacctcc tgatgaattt
     3301 attccaattg cagaacaaac aggattgatt aactcaattg gattagtagt ctttgagaag
     3361 gtatgtagat ttatagctag tgatgagttt gaagatttaa aattggataa tatagctgtg
     3421 aatctttctg tagtacaatg tatgcaaaaa aacttagctg atgatttact ttatcttatg
     3481 aataaatata atgtatcacc aactaaattt aaacttgaaa ttactgagac tgtggctatg
     3541 ggctctttta atataattaa agaaacaatg gaaagattaa ttgatttagg tgttaagttt
     3601 gcacttgatg attttggaat tgcttattct ggagttacta atatgctttc tttaccattt
     3661 tcagtaatta agttagataa gagtttgatt tggtctatga atgaagatag taggcataaa
     3721 cttacagttg agacgattat agcacttata aataaattga atatgaaggc tgtagcagaa
     3781 ggtgttgaaa ccattaagtg tgctgaagat ttaatagcta tggagtgtga atatttgcaa
     3841 gggtattatt tttctaaacc agttccagaa gatgttttta aaaatttgtt gaaagaaaat
     3901 acttttacaa gttaacaccc tttatttttt taattacaac tttgttcatt gacactgcca
     3961 gcgatatatt ataaaattaa cacaataata aatattaaat ttattataca tattattaat
     4021 attaattaat ggagtaaaga tttattatat attttattta attatcctaa agtgagaaag
     4081 gaagatgtga catgaataaa aagaaaatat tagtgccaat tgatgggaca gaaagaagta
     4141 tgcattcttt ggaatttata aaaggaatat ttaaaaaaga tgaagttgaa gtagaaataa
     4201 tgaatgtaaa agaactagta tttattgatg gcatatccct ggctgaagag ataaaaaatt
     4261 ctgaaaattt aggaagaaga atcttggata aagcagcaga gataatggga gagtatgatg
     4321 ttaaagtaca ttttactttt ggatatccag gagatgagat aattagaaaa gcaaaagaag
     4381 ataatgtaga ttttatagtt atgacaaaat ctactaaaaa aggtcttaca agaatgatag
     4441 gttcagtaac agcaagtgta gttaaacaag caaaatgtat agtgatgatt gtaccggagt
     4501 agaattagaa aggtatttga aatatgaata aaaagatagt agcagtttgt gaaagtgaaa
     4561 gaagtttaaa ttctcttaag acagctgcaa atgatttagg atttgattta gtttatgaaa
     4621 ttcaagaaaa tgataatata aaaaatgaac tttctattta tgatatagaa gatgcatcca
     4681 tagtgttatt tgttacaagt gattctatag aaagcataga gaagattgat agatttatag
     4741 atagagaatt ttatgaagtt gatccaaagt atataataga ggatgcaaaa tctatagtaa
     4801 gtgaaatttt aatagactta aattaatcgt gggtgtcgca ctaagaatag agcgacgcct
     4861 ttttatatat tttacacaag aaataaagag gttgtatcaa aatatagata agagtctttt
     4921 tcattgttga aatgatgaaa atatatttga tttcatacaa aaaagagtac ctcataacta
     4981 aaaagttcac tttgagacac tccattttta tatgttagtt gcatttaagg taaaatagaa
     5041 gtttaatcat gttgaaataa ctgaattaca tcttctaaat gattgtacat tgatgtataa
     5101 cctaagtaag agtctttact atcaaatgca atcattatct tgttatggtg gctaatcata
     5161 tccttgagag aatttctata tttaaaacca aagtattggt tagaagaaac tgttttaggt
     5221 attaactcat aatattttat aaaaattgga ttatgagaag ctaaaattat ctctttgtga
     5281 aattgcaagt cagcatcata acattcttct atcaaaccat gagaaacctt atccaattcc
     5341 tctattgact ttaggtaagt atattttatt ttttgaagtt ctttagatgt agcatttaaa
     5401 attgctagtt tagtagcttc gctttcgata agttgtcttg ctcttaaaga ttctacataa
     5461 aattcttgta tgttatgatt tttatagatt tcaccatcat caaataggtc aactttttta
     5521 aatccttcaa ctataggact tgaataaggc acagctctaa gtattccttc cttacagagt
     5581 atatttatgg catttcttac aggtattcta cttatgttaa ataggtcagc aatctttctc
     5641 tcacttggta atttactatt aattttaaaa gttccattta gaatgtttaa tttaatataa
     5701 tcaataattt tttcagtggc atttaagctt ttcataaaaa ctcctaaaca tataattttt
     5761 ttatgattgt attatatcat agttaagagt taaatctact tttttataat atgtataaga
     5821 caggatagag gccaaaatag ctataatagc caagataaag tatccatatt gtattgaagt
     5881 atattccgat attttaccaa ctatcattgg aaatacagac attcctatag cataaattgc
     5941 ttgaaaaaaa cccattgcag tagatttctg atgttttggt acatttttca tagactcgct
     6001 agtaaggtaa gaaaggagta tacctgtaga tatacctggt agtacttgta gtacaaatat
     6061 tatattaata ttttttattg ttggaactaa aaagcaatag gctgaaacta aaataaaaac
     6121 taaaggaatc caaaattttg gtccatactt agtacaaaat ttagtagaag caaagccaga
     6181 agaagcaaca gcacacacca tgtaaaatat agaagataga cctatgaggg tagaactaga
     6241 acctaagttt ttaagaattt gagtagtaaa tgacattgtt gtagacattt gaataccctg
     6301 ttgaattaat gccataaagg aaaaaaatac aagtctttta tccttgcaga tagataaata
     6361 ttttttaatt gatatttttt caggtatttt tttagaatta tgatttttta tatttaaggc
     6421 tagaatcgtt ccaataactg aagacaatac actcatgata cataaggctg tcattcctaa
     6481 tttttcataa aataaagtac tcataacaaa tccaatcaac attcctagat tgtttaccaa
     6541 tattatcgta cttgtagctt tttgttgatg ttctgtagaa aaaaagttgg tatagtgaac
     6601 catgtaagaa atccaagttg atgatgatat tccagataaa atgttagcta taagaaaacc
     6661 attgcctcca ggagaaaaga ctcttataag agatgctaaa ccagcaaaga aaattccaga
     6721 cagtataaat attttatgtt tatttatgga atcagcaaat actccaacag gaagccttaa
     6781 taaacattgt gatattccat atgcacctat tattatacca atcatatttg tagatacatt
     6841 acatgcactt aaatatggat tttggaaagg tatatataca tattgtgaaa accagaaaaa
     6901 tgtaacaata gaaagtaaaa gtaatttttg attagatatt tttttcatat tatcctccat
     6961 gtggtatttt tataatgcaa ataatatacc atttagattt tttaatcaag tactttctct
     7021 attaaaaaaa atttaaatat ataattatta tttacaaaaa aattatactt tatagttgaa
     7081 ttaagaaaac gcttatgata ctataaagtt aacaaatttg aatatataac agtagacgtg
     7141 ttactggtaa tgcaggcaag atcgaatcaa tttttataga ttatctatag agtactatgg
     7201 gtataatcta tttatttggt tcgatttttt tgtttaattg gccataaaac aaaaagccta
     7261 tagttgaaaa tggaggattt tttatggatt ataaaaatat agctcaagaa attctactaa
     7321 atgtaggagg aaaagagaat gtaaatgaag tgactcattg tatgacaaga cttagattta
     7381 aagtcaaaag cgcttctaaa gtgaataagg ataaattatc taaaactgaa ggagtaataa
     7441 ctgttgttga gagtatgggt caaatacaag ttgtaattgg aaataaagta aaaaaagtat
     7501 atgatgaggt cataaaaatt gtacctcaat caaataacat aggtaaaaag aatgaaagtc
     7561 aagaaaagca aggtataatt aattctatat tatcagcagt agctggtata tttacaccta
     7621 caatacctgc tatagcaggg gttggtatga ttaaaggtat tttatcagtt cttgctatgt
     7681 attatatgaa taaaaatgga gtagatataa aagaaacgca aagctatatt atcttaaatg
     7741 ctatggctga ttctatattc tattttatgc ctattatact aggatatact gcggctaaag
     7801 tatttaatgc aaataaaata atatctatgg tattaggagc tacactttgt tatccaactt
     7861 ttactgcttt gatggcaggt gaagaatctg ttagattttt aggattggca gtaacaaaag
     7921 ctacgtatac atcatctgtt attccaataa ttattgctat atgggctctt tcatacgttg
     7981 aaaaagtatt agaaaagtat atacctgagg taattaaaat aataatggtt ccaactttat
     8041 cattggtagt aatgttacct gcaacattat ttttatttgg accaatcgga atttatatag
     8101 gaaatgtcat aaacttttct tataagtata tttatgaatt aagcccagca ttgtgtggag
     8161 catttgtagg tgggttatgg tgtgtgttag ttatatctgg tgctcataga gcattattac
     8221 caataggtat aagtgatgtt gctcaaacag gaagacaaaa tttattggcg tttgcaggag
     8281 ctgcaaactt ttcacaagca ggggctgctc taggagtatt ctttaaaact aaaaatcaag
     8341 gactaaaaac aatttctatg tctgcaacta taacagcttt atttggtata actgaacctg
     8401 caatatacgg tgccaatctt agattaaaaa aacctatggt atgtgccgta atatgtggtg
     8461 catttggagg tgcgataatg ggaatgggtg gagcttatgg taatgcattt gcaaaccaag
     8521 gtgttttaac tatacctgta tatgctgaag caggtgcatt aggtttctta agttatctag
     8581 gtggttgtgc tatagcattt tttggttcag ctatttcaac ttatctagtt ggatttgaag
     8641 atttggaaga gtcttctaat aaggaaaatt catctataaa agtagaaacg aaggatggtg
     8701 ttattgatat aacttcacct gtagagggcg aatgtataga attgtcagaa gtaaaggatg
     8761 atgtatttgc ttcaaaagct atgggagaag gtatagctgt gttacctaca aaaggagtaa
     8821 taacagcccc tactgattgt gaagtagctt ctttatttcc aacattacat gcaataggat
     8881 taaaattaga taatggagca gaaatgttaa tacatgttgg aatcaataca gtagagttaa
     8941 atggtaaata ctttacaaaa catgttaatc aaggagattt agtgaaaaaa ggtgataaac
     9001 ttatatcgtt tgatatagat aaaataaaaa aggctggtta tgatgtaact acgccagtta
     9061 tagtaaacaa tacatttgat taaaaaatag ctacgcacac tcgtgacttt agtcatgagt
     9121 tagtagctaa aatagtcagc atatagggaa acctatatgt agagatagga tagaacctat
     9181 ccaatactac ttgaattgct ggaaacccct aaagctaacc aaactaaaac ataaggatga
     9241 aataaaccta agtgtgaaag tcacgaaagt agaaaaaatt ggttagatgg tataaggtta
     9301 aatcctaagt actttaaaat gggcaatcag caggtaagct ccgaatagga gaaacttcaa
     9361 cgactattcc tcttgaggga agtacactac aag
//
LOCUS       DAEPXW010000122         9241 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.126, whole genome shotgun sequence.
ACCESSION   DAEPXW010000122 DAEPXW010000000
VERSION     DAEPXW010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9241
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.126"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            442..1647
                     /locus_tag="KRM55_003216"
     CDS             442..1647
                     /locus_tag="KRM55_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH1595425.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTNRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1718..1939)
                     /locus_tag="KRM55_003217"
     CDS             complement(1718..1939)
                     /locus_tag="KRM55_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595426.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2080..2679)
                     /gene="recR"
                     /locus_tag="KRM55_003218"
     CDS             complement(2080..2679)
                     /gene="recR"
                     /locus_tag="KRM55_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBH1595427.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2692..3042)
                     /locus_tag="KRM55_003219"
     CDS             complement(2692..3042)
                     /locus_tag="KRM55_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBH1595428.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3101..4738)
                     /gene="dnaX"
                     /locus_tag="KRM55_003220"
     CDS             complement(3101..4738)
                     /gene="dnaX"
                     /locus_tag="KRM55_003220"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBH1595429.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4815..5079)
                     /gene="ffs"
                     /locus_tag="KRM55_003221"
     ncRNA           complement(4815..5079)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KRM55_003221"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5117..5208)
                     /locus_tag="KRM55_003222"
     tRNA            complement(5117..5208)
                     /locus_tag="KRM55_003222"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5172..5174),aa:Ser,seq:gga)
     gene            complement(5209..5664)
                     /locus_tag="KRM55_003223"
     CDS             complement(5209..5664)
                     /locus_tag="KRM55_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBH1595430.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5985..7256)
                     /gene="serS"
                     /locus_tag="KRM55_003224"
     CDS             complement(5985..7256)
                     /gene="serS"
                     /locus_tag="KRM55_003224"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH1595431.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7382..7587)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7715..8596)
                     /locus_tag="KRM55_003225"
     CDS             complement(7715..8596)
                     /locus_tag="KRM55_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH1595432.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8608..9117)
                     /locus_tag="KRM55_003226"
     CDS             complement(8608..9117)
                     /locus_tag="KRM55_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBH1595433.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
BASE COUNT         2960 a         1604 c          975 g         3702 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttctttt tccttttttc
       61 aaggacaagt aatactatat catctttatc tattctagtc aatataattt tttacttttt
      121 ttaatttttt tatttatcat gtattcttta tctttaattt ttaaaactta atgctaagta
      181 aacctgttta tttcataaaa ctaatatata ttctatgctc tattttcctt tttattctat
      241 atttaaattt tttatttaca agaatatttt taatataaca tatttgataa aattaattta
      301 catttctttc acttgtaatt tttgcaatct tgtattagat taatattaaa aataatttat
      361 caataacctt attcacaaag acagttttta tatatcaaaa tataatataa atactatgct
      421 acattttagg aggattttat tatgagcaaa aaagtattaa taatgtctgc ttccactggt
      481 ggtgggcata atagggctgc tctagctatt aaagaagaac ttacttccaa aacacttgat
      541 ggagagccaa ttgaatgtga aataatagat agtttgaaat tagttaataa tacaatggat
      601 aaaataattt caagaggata cgaaaaatct gctatatata ctcccaaagc ctatggaagt
      661 gtatatagat tatctgaaac aaatcttttg tcaaaaaatg aatttaaaga taatctacta
      721 ataacattca tggctaaaaa atttaaaaag cttattagaa gcgaaaaacc agacttgatt
      781 ataggaacgc atccttttcc aatgattgct ctaagtacat tgaaaaaaaa ctttaattta
      841 cataataatg aatcaaatgc ttacacagag catttttata aacattatac aaataccatt
      901 aatgttcctc cgcttatttc tgtattaact gattatacta ctcattctac atggatacaa
      961 aatgaaattg attactatat tgttggtcat gaatatgtaa aagaattatt ggtgtttgat
     1021 ggagttgaac cgagtaaaat tagaacattt ggaatccctg ttgaaaaatc ttttctctct
     1081 cacagagata aagatattgt tctttctgag ttgaatttat ctcctgataa attaactgtt
     1141 ttacttatgg ggggtagctt tggggctgga aatataaaag agacacttga tgaattactg
     1201 gatactaata gagactttca aatacttgta attactggta agaatgaaag cctaaaagaa
     1261 aaaatcgaaa aaaaacttat gtctcgttat catgataaaa atgtatgtgt tcttggatac
     1321 actgataaga tgaatgatat tttagcttct atagatgtat tagtaagcaa acctggtgga
     1381 cttactacaa ctgaggctct tttaaaagat gtacctatga tagttcctta ttatatacca
     1441 ggtcaggaag aagagaatct tgatttctta tctaattgtg gtgcagcact tagaactaca
     1501 aaaaaatata acttgtcaat attactaaaa gttttaatag atgaccctag cagattagaa
     1561 atgctaaaaa gaaatattaa atcaataaga aagtcaaatt cagcccaaaa tatagctaat
     1621 ttaattttaa atataatttc tggttgataa aataaataaa atccctatag tatatatatt
     1681 atctattagg gattttttat tttctaatta tttaatatta aattggttca taaaagtctt
     1741 cttcataatc atactgataa tttttataat tatttctaaa ttcagcattt ttatttcgta
     1801 catttttttt agtttttttc ttattagaaa aacttatatc ctcaaaatca tcatatttag
     1861 gtttatcttt tgatttcatt tttttaactc ttttttcttt cattgcatta tgttcttcta
     1921 agttcataat tggtttcatg ttgcacccct atcaaaattt ttaaatgatt tatacaacaa
     1981 attatacaat acagaagaaa tttattcaat aaatctaaat caaaattaat ttgaatttaa
     2041 ctcaaaaaat tacaaaaatc gaggtattaa cctcgatttt tatatttctc ttctgccttc
     2101 tagtgctttt gatattgtga cctcatctgc atactctaaa tcgcctccaa caggaagacc
     2161 atgagctatc cgagtgactt tgattcccat tggttttact aacctagcaa tatacatggc
     2221 tgtagcttca ccttcaatag taggatttgt tgccattatt atttctttga cttcctgatt
     2281 gccaagtctt tggataagtt cctttatttt taacatatct ggtccaattc catccattgg
     2341 agaaattact ccatttaata catgatactg tcctttaaac tctctcgttc tctccatagc
     2401 tgctacatct cttggatctt ccacaacaca tataacactt gaatctctac ttttatttga
     2461 acacatgcta catgggtctg tatctgttat attacaacaa attgagcaat atcttatttc
     2521 tctttttgca tctataatcg ctttagataa agcttccaca tcattagtat tcatattaat
     2581 aatatgaaaa gccaatcttt gagcagtctt tcttcctact ccaggaagct ttgaaaattc
     2641 ctctataagt ctcgttatgg gacctgtata aacttgcata aataccacct actagaataa
     2701 cccaggtata ttcatacctc cagttacctt actcatttga cttgcttgta tatcatcaat
     2761 atttctcaat gcttgattta ctgcacttaa aactaaatct tgtagcattt ctatatcatc
     2821 tggatcaact acttctggct tgatagttat atctataact tcttttttac cattaacttt
     2881 tacagtaact gctcctccac caactgaagc ttctacttct ttactttcta actcttgttg
     2941 agctttttgc atattttctt gcattttttg agcctgcttt aacaagttgt tcatatttcc
     3001 accaccaggc atcattccgc ctccaaaacc ttttttagcc ataaacacta ttcctcctaa
     3061 acttattttc attttattat tatatcataa tagtatttta ttatttactc tcattttcat
     3121 caatactatc ttttatttct aatatctctt cactcactat gttctttaat atttcctcac
     3181 caatgtcctt tttctcttta acttcaagat ttatatcttt aacttctgat gtcagtacta
     3241 tttttacatt aaaacttcta tttaaaacat ctcttattgt tttttctaaa taatttattg
     3301 tatcttgaga gctcagtcta gtttttgcaa aatcaaattt atcatcaaat ataacataca
     3361 acatattaga atatacatta aaacttttta cttcacttaa gagtgcgtat attggcattt
     3421 ttttatcttt tttaatttgt ttaagtatat tcttccaaga tgactctata agtataacgt
     3481 cctcattttt tacatcttca taaactacat tttcttgttt tacatctatt tctctatcga
     3541 cctcatactc tttttcttta ttattcccaa ttttttcaga cttaaagttc cccagttcaa
     3601 tcattttttc taagttctca actcttttta taagagcttc tttactttca tcaaacattg
     3661 gttgagcaat tttcattatg gttatttcca ctaaaaccct tggatttgaa gatgacttta
     3721 tatcatcctg agttattgat aatatattta aaatccttat taaatcattt atatctatat
     3781 ttttagactg aattttaagt tgttctatag tttcttctgg taatgaaatt atttcatcca
     3841 attctgatga aaccttacat accattaaat ttctaaaatg atcaattaag tcatttataa
     3901 gatttcttat atctttgccc cataagacaa attcatttaa tatctcaaga gactttttag
     3961 tgtcctgctc tacaatacat tgagacaatt caaataattg ttctatattt acgcttccca
     4021 ttaattcaac aacatcttta taatctatct tactttctcc aaaagacata cattggtcta
     4081 atatactaag tgcatctcta agagctcctt gagaatttct agctattaaa ttaagagctt
     4141 tatcatctat atcaattcct tcatcttcac aaatcttttt cattctaagg gtcatatctt
     4201 taactgtaac tcttttaaaa tcgtatcttt ggcatcttga taaaatggtt gcaggtattt
     4261 tgtgaggctc tgtagttgct aatataaaaa ttacatatga tggaggttcc tctaaggtct
     4321 ttaataatgc attaaaagct ccttgagaca acatatgaac ttcatctatt atatatactt
     4381 tatatttagc attggctgga gaatatttca cactttctct aagctctctt atatcatcta
     4441 cactattatt tgaagctgca tctatttcta caacatccat tgtattatct tttaacacag
     4501 attcgcatat ctcacactca ttacacggtt cttcatttat tttattcaaa cagtttactg
     4561 ctcttgaaaa aatctttgca gtagatgttt taccagtacc tcttgttcca caaaacaaat
     4621 aagcatgtcc tatattatca ctatatattt gattctttaa agtcttaata atatgatctt
     4681 gaccaataac atcttcaaat ttttgtggtc tatatgctct atataatgct ttatgcatct
     4741 ttttacctct ctttagcaaa attaataaaa aaatccctca ttatctaagg gattagtctt
     4801 ttatatatta aatgctgtac accatctatc gacttaattc cataggcgtt accaaaacag
     4861 ttagctcaac ttaggcaccc ccacggcaca caaaagtgat cacttaccgc tgcttccttc
     4921 cggatctgac ggggttcatg agctttcatt gcgcaggacc taagcatcaa caccacttat
     4981 ttagggcggc cctacagaaa ataagccttt agatggaatt caatcctgct atagcggatt
     5041 gcaggttaca gggcaccgct acctccccat ctagtacagc aaaattacaa ccatatttaa
     5101 ttactttcat tgtttctggc ggagagagtg ggatttgaac ccacgataca gttttaccca
     5161 tatactcgct ttccaggcga gcgccttcga ccactcgacc atctctcctt aatctctttt
     5221 tctcaatgcc ttaaaaaatt cttgcaatat gatcgagcat tcttcttgca aaacatcaaa
     5281 agctactttt acattattat tattaaaata atctaattta aactcatgct gtttttctat
     5341 atatgaattt tttacatgtc ttgtccctat tataagcttt tttattctag aattaactat
     5401 tgcgccacta cacattatgc aaggttccat tgtaacatat aaatcacaat cagtcaacct
     5461 ccaaccacct aatttttctg atgcttgttt tatcgctaaa atttctgcat gtgccgtaga
     5521 gtcttttaac gtttctgtaa ggttatgagc tctagctatt atttgattat ctttaactat
     5581 aatagcacct attggtgttt cttttttatt atatgcttta tatgcttctt ttaatgcttc
     5641 tttcatataa aatgaacttt ccataattcc tcccaaaact tataacaaac ttatcttatc
     5701 ataattcatt ttataattca acttaatttt attttgttta tttaattatt actatatata
     5761 gctatatttt tttaaaatta gttctaaaat aatttttaga tattcataca aaagtgtttt
     5821 ataaaaatat ttagtgtttt atgatgaaaa ttctgctgtg taaattaaca taaaaaaact
     5881 atgaaattaa tatttataat aatttcatag tttttttatt tattgtttac tcataatata
     5941 ttctcttcat caaagcatac tctacatata caattaatat aaatttattt tataacatca
     6001 acacccatat aaggtcttaa ttcttctgga actactacag aaccatctgc ctgctgataa
     6061 ttttctaata tagcagccaa acatcttcct attgctaatc cagaaccatt taatgtatga
     6121 acatattctg cttttgattt tttatctctt ttaaatctta ttcctgctct tcttgcttgg
     6181 aaatcttcaa aatttgaaca agaagatatt tctacatatc tattgtaact tggcatccaa
     6241 acttctaaat catatttaaa tgcagctgta aatcccaaat ctcctgtaca tatttttaca
     6301 actctatatg gaagacctaa catttgtaac atagtttcag catcatgagt taatgattct
     6361 aattcattat aagaatcttc tggtttaaca aatttaacta attcaacttt attaaattga
     6421 tgttgtctaa ctaaacctct tgtatctctt cctgctgaac ctgcttcaga tctaaaacaa
     6481 ggagtatatg cacagtattt aattggaagc tctgcaacat ctaatatttc attagcatgt
     6541 atattagtaa caggaacttc agctgttggt attaagaaat actctaatcc ttctatttta
     6601 aacatatctt cttcaaattt aggaagttga ccagtcccta taaaactatt tctattggcc
     6661 ataaatggag gtaagacttc cgtatagcca tgcttagctg tatgagtatt taaaaagaaa
     6721 ttcattaaag atctttctaa tctagctcct aatcctctat ataaagtaaa ccttgaccca
     6781 gttattttcc ctgctctttc aaaatctaaa atacctagac ctgtacctat atcccaatgc
     6841 gctttatgct caaaatcaaa tttagtaggt tctccccaag ttcttatttg aacattgtct
     6901 tcatctgttt caccttgtgg tacctctgga tgaggaacat ttggtattct cattaatgta
     6961 tattccattt ttgcttctac ttcttttact ttctcatcaa taccttttat cttatctgat
     7021 aactctttca atcttgcctt ttcttctgtt acatcttttc cttcttttat taattgaggt
     7081 atttttttag aatttacatt taactcattt ttcataactt caacttcttg aagtatttct
     7141 cttcttttat tatctaattc cactacagca tcaaggtcaa attctctttc acctcttctt
     7201 tccatagctt ttttgatatc atctagattt tctcttattc ttttaatatc taacatatta
     7261 attcctccta ataattttga taatataagt tataattcca acttaattta caaacattat
     7321 acttgtaaac tcttagttta aacaaatttt aaaaataaaa aaagacctcc gtttacccta
     7381 taaaagggac gaaaatcttt tatccgcgtt gccaccctaa ttgactatac taaaatgtat
     7441 aatcctctca gacctataac gtaggtaaac gtctagcttt aactagaagc tctagagtag
     7501 attcaaaaac cattgtaatg agttttcacc atccactcat tctctgaata caatctgttt
     7561 tttactattt tccttcacag ctttttaact aattgtttta tttgataatc attatattat
     7621 atatattaac atctttcaat actattattc aaattttttt agaattttct ttaatttttt
     7681 atattaaatt cattttttct atttaattaa gaccttatct tttatccatt gtatttagat
     7741 tacctgtatt attaaataat aatgaagaag gaacaaatgg aacttttata tcattctcat
     7801 caaatttatt ttttaccttt tccattacat caaaatatac atcccagtaa tcatcagttt
     7861 ttacccaagg tctagcaact atttgcatgg tgttatttcc tatagagttt aaacctatta
     7921 taggctttgg atcatttaat attctttttt cgtttgtaaa aatttcattt aatatagact
     7981 taactacatc tatatcacta tcatatgaaa tattatatga aaaatctatt cttcttttgt
     8041 tttgatgtgt gtaattaatt atattattac ttgtcagttg aaaattaggt ataattatag
     8101 ttttattatc tggcgtctta agaacagtgc taaatatttg tatgtcagaa actgtacctt
     8161 ctacacctga accttgaata taatcaccta tattaaatgg cttaaaaaat aaaataatca
     8221 taccagagcc taaatttgat aatatttctt taaaagctaa acctatacta aatccagcag
     8281 ctcctaacac agctacaact gatgtagttt gtatccctat aatacctaag cttatcaatg
     8341 atataataga taacatagat atatatattc catatacaat aaaattattt acacctttac
     8401 tcattccata tttgattaga aactttgaaa ccatccttct tactatttta gatatataaa
     8461 tacctatcac aaatacaatt attgcatata taatatttgg tatattatca ctaaaattat
     8521 cgagcatatt ttctaaagtt ctcttagtta tattgctatt tgttgaggca gtcttagcca
     8581 atgataaaaa attcattcaa ctcctcctta tgataatatt ccgttgtcct ttaactcttt
     8641 tactatagct tctatagttt cttcttttat tgcctcaatt gtatgaatat ggctacattc
     8701 tgtcagaacc gataattgtt taaattcatt tgtctcaact ttcttcataa agttgtctat
     8761 atccatttta gaataaatat taagttctgc agttatctga ccatatgttg gatgatttac
     8821 aatgacatct tttataatac cacctaaatc tacaattatc tttaattcat cataaatttc
     8881 tttagaatcc ttatgatttt tacactttat ttgttttgta aaatacggtt gattatatat
     8941 tatatatcct tgaggtgtag ctattatttc aaatcctcta gctcttataa gggctatatc
     9001 ttgaactatt acttgcctac ttacatttaa tagttcagct agtgttccac cttttacagg
     9061 atgcttagat tcttttaaaa tatctattaa tttacttctt ctttcattag aattcatatt
     9121 acaccttctt tccaaataaa aactttacct atactatata attttatatt ttatcttatt
     9181 ataaatcaat attgacttta tattctattt aatcttaact tttataataa ataaaaaaag
     9241 a
//
LOCUS       DAEPXW010000123         8967 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.127, whole genome shotgun sequence.
ACCESSION   DAEPXW010000123 DAEPXW010000000
VERSION     DAEPXW010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8967
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.127"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(85..693)
                     /locus_tag="KRM55_003227"
     CDS             complement(85..693)
                     /locus_tag="KRM55_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBH1595434.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(802..3540)
                     /locus_tag="KRM55_003228"
     CDS             complement(802..3540)
                     /locus_tag="KRM55_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBH1595435.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINVCISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3688..4479)
                     /locus_tag="KRM55_003229"
     CDS             complement(3688..4479)
                     /locus_tag="KRM55_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1595436.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4515..5171)
                     /locus_tag="KRM55_003230"
     CDS             complement(4515..5171)
                     /locus_tag="KRM55_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595437.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5164..6129)
                     /locus_tag="KRM55_003231"
     CDS             complement(5164..6129)
                     /locus_tag="KRM55_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBH1595438.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKNLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISNKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6235..6341)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6631..7575)
                     /locus_tag="KRM55_003232"
     CDS             complement(6631..7575)
                     /locus_tag="KRM55_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH1595439.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSASIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATVIEPIELKHLIKSKVLELYNHHCI"
     gene            7686..8153
                     /locus_tag="KRM55_003233"
     CDS             7686..8153
                     /locus_tag="KRM55_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595440.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8323..8922)
                     /locus_tag="KRM55_003234"
     CDS             complement(8323..8922)
                     /locus_tag="KRM55_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595441.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2917 a         1490 c          870 g         3690 t
ORIGIN      
        1 atcaaactaa aaattctata aaaaaataag atacatacct ataaaatacc ttcctataga
       61 tacatatctt acctatataa aaacttattc tatataaaaa cgccataaaa aatcttttgc
      121 ttcttctgca taatctatat ttatacgttt actagttttt atatctaact catctttact
      181 aaatactttt tttcctttat catcataata aaaatcactt atatataatt cttcacccat
      241 tatactctta ctatttagac ttctatctat ttttaaagct ttgcaaagtt ttcctggtcc
      301 gttagtaata ttttttactt gatatttact caactcagtg taagctttgt tgtatctatt
      361 catagatatc tcatctaaag aagttatagg ctctacccct cttattaata cacactctgg
      421 cacattttct atatttgcag ataaattcaa gcaattatac ataccataaa ttaaataaac
      481 atatatatgt ccaccatcta aatataatgg cttagttcta tctgtctttt tattgccata
      541 tacatgtgct cctttatcat ttacacccat gtatgcttct gtctctatga ttttggtaac
      601 aattacttta ttttcatatt tccttattag atatttacct aatattgatt tggctaaatc
      661 aattccattt tttctaaaaa aatccttttc caaaatttca cctcataaaa tttatttaaa
      721 acgcatcaaa tacaactaaa gtaataaata aaattaactc ttattaatgt gatatatata
      781 aacaataaat ttagacattt attatttata tatatcaaaa aattctatct caaacttttc
      841 aatattatca ttgtaatttg aattatcata tacttcttca acaacctctt taattgggaa
      901 tataactttt acattagttc cttctcctac cttactatct atgtaaatct tcccattttg
      961 aatttcaatc aatgattttg taaggcataa acctatacca cttccaaatt catttgatat
     1021 accactgttt tcaatttgtt taaatcgatt aaatatatca tttaattttt ctttgtctat
     1081 gcccactcca gtatctttta taattatctc tactgtttcg tcttttttat atatacctac
     1141 aaggatttct cctccttcta aagtaaattt tatagcattt gataatatat ttagtattat
     1201 tctttctatc gattctgggt caagccctac cataacagtt tcttcatctg tatcaaaaat
     1261 taaatctatt cctttagact tagcataact actaatagat gtaactattc tttctgttat
     1321 gtcaataata tcaaaattaa ctgctttaat cttatatatg tctgacttaa cttgagaaat
     1381 atttattata ttatctatta atctcaataa tctaaacata ttttgtttag ttatttttat
     1441 atgttctttt agtatatcct gaaaatcaat tatttttcct tttttataaa ggttttcaat
     1501 aagttgaact gaactatata tattatttaa aggtgtctta agttcatgag atatattagc
     1561 ataaaactcc atcttcattt ggtcatactg tctttgtttt attaatgctt ttttaagtct
     1621 ttcagactct ctttgcacac ttaaatcttt aataattctc actctacttc ttttctgtcc
     1681 aaagtataat gttcttgata tcatttttac ttctttaatg tgattatttt catttactat
     1741 atggatactc ttctctcttt ctcctatatt taaattgttt atgtattttt ttactaatat
     1801 atttctatat ttttgtgttg taactcctaa tacatcacta gaaattccga acaactctct
     1861 aaaggctcta tttgtatata gtactcttga tgtacttaaa tcctcaagaa aaatagcctc
     1921 tggtataaca tccagtaatt tttcatatat tattttttgt tcatttactg ttctaagaat
     1981 atttatctct ttagttatat ctctaaatgt aagcaattta aagagtttat tatctgacca
     2041 atagtctcca actctaactt cttcaacatg ctcttcacct tctgagtcag acatcacaaa
     2101 attaactata cagtttgctg tgtcattgta acttactatt tcagctttct tttcttgtgt
     2161 tagatttaat cttttaaatt ccctattgtc aaagaaatct atgttaaaag tttcaaaata
     2221 ttgttctaat gtcatatcga ctaaatcact tgaaacacat ttaaaactct tttcatattt
     2281 tttatttata cttattacct tattcttctt tatgccacct tcagcacttc ttacaagtat
     2341 aggagatgga atatttagta taatgttttc atagtcttta tttatatttc ttatttcttc
     2401 atctattttg atttcatttg taatatcatt taaacttatt aagtaattgc tttcatcttt
     2461 attattactt aaacttaaca aataaatttt atcatttaac tctaccagtt tatcaattat
     2521 acttatatcg ttatcaaatt tcttcaattt ttcagcaact ttttcatctt cctttataaa
     2581 agttaatatt ttataataat tattcatatc ctttgaaaat tcatctttaa atttattatt
     2641 tgtgtaactt atattaaaat catagtctgt tactatccat acatttggta ttgtatccag
     2701 agcttgtcta agtaattctt ttctctggtc tatgtagttt tttaatgttc tttgtataat
     2761 catatccttt tctattgcta aatttatctt tcctaattgc tctgactttt tacttaattt
     2821 tttattgatt gaatcaagtt cataatatgg atacactact ctattattaa gactgtatac
     2881 atatacataa taagtatggt tacataatag taaatatatt actcctatta atctatctga
     2941 atctactata ttaatcttag aaattgctac aaaacatata atagttgtaa aaaaaacaaa
     3001 atatgttaaa tcttttatta acttatagtg ctcaatgtta ctatcaagtt tattcaacaa
     3061 atatagtaaa ttaaacatag atatacaaac attaattaat ataataatca tattccagtt
     3121 aatatcacta aaaatatttc ttataaagta atctaatatc acaaaagcac tataaaaaat
     3181 tagtattggg cttattctta gtttttttac tttagaaatg gttaagtata taaaagtaga
     3241 catattaatt atgcttaagt taagcaatac aatttggaat ttttgaattt ttaaatttac
     3301 tactcctaaa atacttacaa aaactaatac aagacaccct actttcaata tatttataaa
     3361 ttcatctgtt ttaaagctac ttatataaac tatagaatat ccaaatatcc aaagtaaaat
     3421 tattctatac atatttatag aaactgtata caaatttata tttaaaagtg caataaccaa
     3481 aaataaccca ttagctagta tatagacctt attcttactt aaagttcctt tagattccat
     3541 attccccacc acttcttcat ttttatatag ttttacctat aaatatgtta ccacaattct
     3601 tccaaaaaat ttgtcacttt ctagttataa aaaaaaatga gtaaatattt ttaattttac
     3661 tcattttgta gattttgtat attcagttta aaaagctgga actatacttc ctttatattc
     3721 atcttgtata aattttttaa cttctttact attcatagcc tctgataaag ccttaatctt
     3781 atcactatct ttattatttt ctctacaagc tattatattt acatatggag aatcacttga
     3841 ttctattact attgcatcct tagtaggatt taagttagct gttaaagcat aattagaatt
     3901 tattactgct ccgtcaacat cttttaatac tgttggtaat tgctctgcat tcatttcttt
     3961 tattactata tttttaggat ttttagttat atctttttta gttataagct ctccatcttt
     4021 tacttctatc aatttatttt ttgctaataa tttaagtgct ctagctccat tagttgcatc
     4081 atttggcaca gctataacag ctccatcttt taattcatct aatgacttaa ctttttctga
     4141 atagaatccc attggctcta tatgaacttt agatgtataa gtaagtttat atcctttctc
     4201 cttcacagtt tcctctaaaa atggaatatg ttgaaagaag ttagcatcca aagacccttc
     4261 atctaaagct gtatttggaa gtacataatc atcaaatatt tttacttcta aatcatatcc
     4321 tttttctttt aacaaaggtt ttgcaacttc caatatcttt gcatgtggat ttgatgaagc
     4381 tcctactagt atttttttat cctctttgtt tgaacaacct actgctgata ttgctattgc
     4441 tgacaccaat gctactgata ataatttctt taatttcatt tttactcccc ctctttaaaa
     4501 tgtttataat taatttattt tagtttctta taagccagat ttcctactcc ctggattatc
     4561 tgaactaata ttataagtgc tattacagta tataccatta ctgctgtatc aaatctttga
     4621 tatccataaa taagtgctat attacctaat cctccagctc ctactgcacc tgccatagct
     4681 gtataaccaa gtatagatat tattgataat gtaattccag atactattga aggcatagct
     4741 tcctttatca taactttaaa tactatttgt ctttttgtag ctccaaaaga ttttgctgct
     4801 tctatcaatc ctttatcaac ttcatttaat gagctttcta taattctagc gataaacggt
     4861 gctgccccaa tagttattgg cactattgca gcagtttccc ctatacttgt tccaacgatt
     4921 aatctagtta ttggaatcat tgcaactata agtatcataa atgggaaact tctaaatata
     4981 tttactataa atcctaatgc actatttatt gtgctatttg gttttaatcc atctggtttt
     5041 gtaactacta atatgattgc taatataaat cctaatattg ttgccactat agttggtact
     5101 ataaccatat acaaagtttg taacaatgca tttggaaata gtgttgttaa aaagtcaatt
     5161 aaactattca tttatcattt cctcccatct tatgccctta ctagttagat attgttttac
     5221 ttgctctcca cttttatttg aaatgtttat aataagtgaa cctaaaatat catctttaaa
     5281 ttgttctaat ttcccaaata ttatagacac atctatattt agttctcttg ccatagtcgt
     5341 aataatagct tcattagaaa tatctttagg gaatagtatc tttatatttg ttccttttgg
     5401 caatattata ctttcttcac ctattaattt tctaagtcct ttagtatttc ttaagaatat
     5461 ttcttctgta tctcctacct ctaatacttc tccattttcc attattgcta ctcttccaca
     5521 aatctgcttt ataacttcca tttgatgagt tacaactatt attgttattc ccaagttttt
     5581 atttatatct tcaagcaatg aaagaattga ctttgtagta tttgggtcta atgctgaagt
     5641 tgcttcatca caaagaagta cttgtggatt tagtgctaaa gctctagcaa ttgcaaccct
     5701 ttgtttttgt ccgccactta gatttctggg tttatcattt ttcttttcag atattccaac
     5761 tacttctaat aactctaaaa ctcttttttt aatttctgcc tttgagtatc caaaacattc
     5821 taatggcaat gctacattat caaatacagt ttttctttca agcaatgaaa agtgttgaaa
     5881 aatcattcct aactcttttc ttaaatctct catttgcttt tcattcaatg actttacttc
     5941 tttatcagaa acaagtacac tgccttcttg gtattcttct aatccgttta tacatctcag
     6001 tagtgttgat ttccctgcac cactatgacc tattattcca aaaatttctc cagattctat
     6061 ttcaatactt acatctttaa gcacttgaat ctttccataa tacttattaa cattttttat
     6121 gctaatcata aaatttcctc ccatatattc tgctcagttt ttatgtttat cctctcttat
     6181 gtattacaac aaaataaaag cccgagtata aactcaggct tagaaagcta tttatactca
     6241 tctatcaact atattagttg caggatttag caccaatgta tataaaatat actggttgcc
     6301 gggtttcaaa gggccagtcc ctccaccact cttgataaga cgttatttaa tttaattcta
     6361 ttatcatttg ttgctatgtt atatatgata tattcattaa tagtatttgt caataaattt
     6421 atttaaattt tttatttttt attatcgtta attaactatt tttaattagt tttctagctc
     6481 ctaacacttt atattttaat gtctatataa ctatagaaca tcattataag aaataaatta
     6541 aataacatca atctatctaa atcatctgta aagtaaatta agaaaattaa cattttatcc
     6601 aaactctatc ctactattaa ataaaataat ttaaatacaa tgatgattat atagctctag
     6661 tactttagac tttatcaaat gtttaagttc tataggttct attactgtag catttttccc
     6721 aaaagttaaa aaatattcag ccacccagtt aagtgtagat tttggtatat acatatctat
     6781 gtatccacct ttagacaaga ttttcaaccc tcttgccaac aaaaattctg tttcacaacg
     6841 ttttactccc tcatctgtca aattaatttt aatatgataa tctgtaccta cttccatatt
     6901 cttaagataa tcatgtatag aagataaaac cttatatttc ttacttgata agttttctat
     6961 actcaaaatc ttcacaattc tgtctacacg aaattcctta atagatgctg attttataca
     7021 gtaagctgga caataccaaa gtccattcat ggcatacaaa ccaataggaa caatggtacg
     7081 tacactattt ttttgctttg atgaatattc aattttaatt gtagattcat tcattactat
     7141 attaaacaat tctttcaata atggtgttga acagtgccta tctggtgtcc aaaaaacaaa
     7201 tttacgcctt atattctcaa tattatattg aatatcattt ggtatacaat ttaaaaattt
     7261 ttttaaaaca gaaatagttt cttgctcaaa tggcaaatca ttataatatt ctagtgactg
     7321 atatgcaaag aatatagatt ttacctcact ttctgaaaat gcaatcggtg gaagtatacg
     7381 ctctttaagt acatgatatc caccagccgc tccaactttt gaatataatg gaaatccaat
     7441 actctccagc acctgtaagt ctcttaatat agtacgtttt gatacagaaa attcttctgc
     7501 taattctcct gctgtaaaac ttctttttgc atttattgtt atcatcagtt caattaaacg
     7561 ctcagctctt gacatattta tactcctaat ttaaatatag tgacaataat tgtcactatt
     7621 atatgataag atattcttac atttaaagca ataataatag taaagaaaga agggactgat
     7681 actttatgga aaataatact attaaggctg atgatattat caattattgt ctatcaaact
     7741 tagatgatgt tttattaatg aatagttggg gggaacgagc aatttactac aatcctaatg
     7801 gtattttaaa gcgaggagta tatgttctta ccattaaaga aaaagacagt aatcatgata
     7861 aaggttcgtt ggttagtcgc ccaaatgtat accgtgtgaa tataggatta aaaaaagaaa
     7921 cttttattga aatgtttgga tatattccaa agcgtccagg tgtaggtcaa atagttgata
     7981 tggattttga ttttacaaaa ttggacacaa tcatgccaca tcctatctac tcatggatgg
     8041 gatggatatg cgtcctaagc cctactgaaa agacatttga gaactttaaa actttaatag
     8101 gagaatctta caattttgca aaacaaaaat ttaaaaagag aaaaaacaag taaaaacgta
     8161 tgaaaataat ccctaaataa attataataa aaatattaag gttacaagat aaaaattaat
     8221 atcttaataa catgcaaaaa agcgaagcca aaaaatgtat tatttataag gcttcgctat
     8281 atctcaaata atttatttca aatttcaaaa ctatttattc tattatttct tattatttcc
     8341 tgttattcct aatctatcat tcatatcttt tatcattttt ctaaaaccac tacctatatc
     8401 atttccaaca tcttcagttc catgaactaa ttttataaag tcattttgac cttttttcat
     8461 atcttcatca gataccttat ctaatttttc tattctctta tctatgtctt ttactaatct
     8521 ttccccttca gcgattaggt catcattcat tttctttaac tctgtatctt ctgttttacc
     8581 atctttttta agagatgtta caaatgattg tattttatct ctactatctt tatatgcagc
     8641 ctttacatca cttagatatt tttcatttcc tggatattct ttatctttaa actgattatt
     8701 tatactttct ggagtatcat aaatagaata tctatttaga cctgctatat aatcattata
     8761 gcttgttgaa taataattca tatatccttc attattattt acagattcat taggattttt
     8821 tcctgtattt tcacttggtt tttcattatt tttagtacat gcagttatac ctatagctaa
     8881 tactagtgct aatcctacaa ataaagttct ttttaatttc atttttatta ccctcctaga
     8941 tgttttatac tataaaaaat tttaata
//
LOCUS       DAEPXW010000124         8965 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.128, whole genome shotgun sequence.
ACCESSION   DAEPXW010000124 DAEPXW010000000
VERSION     DAEPXW010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8965
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.128"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            108..449
                     /locus_tag="KRM55_003235"
     CDS             108..449
                     /locus_tag="KRM55_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBH1595442.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            600..1013
                     /locus_tag="KRM55_003236"
     CDS             600..1013
                     /locus_tag="KRM55_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBH1595443.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1215..1856
                     /locus_tag="KRM55_003237"
     CDS             1215..1856
                     /locus_tag="KRM55_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH1595444.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1880..3133
                     /locus_tag="KRM55_003238"
     CDS             1880..3133
                     /locus_tag="KRM55_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1595445.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3179..3829
                     /locus_tag="KRM55_003239"
     CDS             3179..3829
                     /locus_tag="KRM55_003239"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBH1595446.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3880..4476
                     /locus_tag="KRM55_003240"
     CDS             3880..4476
                     /locus_tag="KRM55_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH1595447.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4489..5328
                     /locus_tag="KRM55_003241"
     CDS             4489..5328
                     /locus_tag="KRM55_003241"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBH1595448.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5573..6727
                     /locus_tag="KRM55_003242"
     CDS             5573..6727
                     /locus_tag="KRM55_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBH1595449.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNSKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7033..8730
                     /gene="ade"
                     /locus_tag="KRM55_003243"
     CDS             7033..8730
                     /gene="ade"
                     /locus_tag="KRM55_003243"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBH1595450.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKLYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
BASE COUNT         3671 a          866 c         1578 g         2850 t
ORIGIN      
        1 taattattta aatatcttaa gtaaatcagt cttacatata tttccgatag attatattga
       61 taaaaaacac taaaattaaa ttaataaaag tacttggagg gatggaaatg aaagaggaaa
      121 attttattaa tgttgaatac gaggataaac gtttttcaat taatagtaaa gaagttttgt
      181 acatagaaaa gcaagagtat gaagtaaaga tttatactga aagtggtaat tatgaagttg
      241 gagaaaatgc tccttgtata agaaaactat tgaaagaaga aaattttttc aaatgcagta
      301 atagttatat tgtaaatcta gacaagtgtg aattttatct cagcaataat tgtatttttg
      361 tgaataataa ttttataaga attttaggtt cagaaagaaa aaagaaatta aaaaagaaat
      421 tagaaaaatt atatgattat gaagattaat attgagaggc tgtattttat acagcctctt
      481 tatttattga ttgtattatt aataaatttt aaattatgat aaaatataaa acaagtaact
      541 tatttcagaa taaaatactt tttaaaagaa agggacgaga tatgggagat tataataaaa
      601 tgcttgaatt aaagaataac ttaggtatca gtgaaagaaa gttaaaatat ccttgtatct
      661 ataaacattt caaagggaaa tattatgcta caatgggtct tagcaaggct attgatgata
      721 tagaaaacat atgtgaaata tatggtaaag aaaatttaat ccaaaacaga aataaatata
      781 aattagttat tagacatact gaaagagaag aagatatcta tgtttatagg gatttagatg
      841 gaaactttta tcataaaaaa gaagaagata ctaatgattt agttttatac aagaccttat
      901 atgatgatac aggaatattt gcaagacctt tggatatgtt tttagaaaaa gtagatacag
      961 ataagtatgt caattcaatt caagaataca gatttgaaga agtatataaa taatataaga
     1021 gaaatatgtt tataaattta gaaaaattct ttaacagtac aataatttgc agaaatacaa
     1081 atgagattta ttgtaaataa tatgttagat tagattataa aatagaaaca aagtaaagta
     1141 ttatatgata taattaagtt ttgagaagtg ataatttata tttaataaaa aataggcata
     1201 tattaggagg acatatggga aatacttttt atatagtaag acatggacaa acggattgga
     1261 atatattggg aaaaacacaa ggtcatggta attctgacct tacgcctcaa ggtatagaac
     1321 aggcaaaaga actttctgaa gatattggca agtattcaat tgattatatt tttagtagcg
     1381 accttgggag agcaatgcaa acagctcaaa ttttaggaga taagctcaat attgaagttc
     1441 aaaaaactga ggcacttaga gaaatgggat tcggagtttg ggaaggcctt ttaataaaag
     1501 aaattcaaaa agattattca gatatatatg caacatggag aaatgaacca cacttagtaa
     1561 atataccaga aggcgaaact cttaagatta taaaggaaag agtagatgct tttataaagg
     1621 aactaaatga aaaatatgat aataaaaata taattcttgt tacacattca attacattga
     1681 gggttatgtt gttgtcattt ttagaatcag gtatggaaaa tatatataga attaagcaag
     1741 ataatactgc tttaaatata gtagaattta aagattatgg gcctgttata gtaaaaatga
     1801 atgatacaag tcatataaaa aatcatgtaa agataaataa ttctgcactg gagtaggaat
     1861 caattataag gagaaattta tgagtaaagt tatagtagtt ggtggaggag cttctggaat
     1921 gatggcagct ttgtcagctt caaaaaacaa taatgaagta atattagttg agagaaatgg
     1981 agaattagga agaaaactta gggcaactgg tggcggtaga tgcaatttta ccaataatag
     2041 agagatagaa gatttttttg ataaagttgt cagtaataaa aaatttctct atagtagttt
     2101 ctatacattt acaaataaag accttatttc gtattttgaa agtagaaatt tggaatataa
     2161 gattgaagaa gaaaatgacc acaaagtata cactaaaaat gataaatcta tagaagtaat
     2221 agaagtatta aataaagatt tactcaatca caatgtaaag ataatgtata ataagaaagt
     2281 tatagatatt ataactgaag aaattgctct aaaagatgat tctaataagg acaagtcaaa
     2341 gtatctaata aaagggatta ttttagataa tggagataaa atactaggag acaaggttat
     2401 tatatcaact ggaggagtga gctattcaaa gacgggttca gatggttcaa tgtataagat
     2461 tcttaaaaag catggacata cattaaacaa actatatcct gctttagttc cacttacaat
     2521 agaggaaaaa tggattaaag atttacaagg aatatccatg aagaatgtgg aaatatcttg
     2581 taagattaag aaaaggaaaa tatcaaaatc tggagacatg ctatttgccc attttgggat
     2641 aacaggacct tgtgttctta taatgtcttc ttatattaac aagattattg aaaaggaaaa
     2701 ggtagaatta aatatagatt tcttaccaaa tttaagtact gatgaaatct ctagtataat
     2761 cagagcattt ccaaataaaa atgttctaaa taatcttaag caaatactac ctcaaaattt
     2821 cttaaaagag attttttctc tattatcttt agttgataaa aaggcaagtg atttgtctaa
     2881 ggcagatgaa attagaatta ttgagtatat aaaaaatatg aagctaactt gtaatgggac
     2941 tacaggtata aacactggta tggttacttc tggtggtatt tcagttaaag aaattaattc
     3001 ttctactatg gaatctaaat tagttaagaa cttatttttt acaggtgaag taattgatat
     3061 agatgcagaa actggtggat ataatttaca aatagcattt tcaactggat atcttgcggg
     3121 tataagtgta taaatataat tttttaataa ttaaatatga ataaatagag gtgtatatat
     3181 gggtaattta gttatagctg tagatggtcc agcaggagct ggaaaaagta caatagccaa
     3241 gatagtagca aaaaagctaa atataaatta tatagataca ggtgctatgt acagagcagt
     3301 tacttataag tgtttaaaaa gtggtattga tgtcaataat gaaaaagaag ttattcaaat
     3361 agctgaaaat tcggatatag attttaaaga taacaatata tatttggaca aagaagttat
     3421 aaatgaagaa ataagaacaa tagaagtaag caataatgtt tctaatgtag caaaaataaa
     3481 agaagtaaga cagttgatgg ttgaagttca acgaaaaata ggaatgaaaa gttcagtaat
     3541 actagatggt agagatatag gttcatatgt tttcccagat gcagattaca aattcttttt
     3601 agtagctact ccagaagaaa gaggaaatag acgctataaa gaactttgta ataaaggata
     3661 taatactact ttagaagaag taattgagga tataataaga cgagatgaaa ttgattcaaa
     3721 tagagaattt gcaccattgg taaaagctaa tgatgcacta gaaatagata ctacaggaaa
     3781 aactatagaa gaagttgtag aagaagttgt atctaaaata aatctttagt tttttatgca
     3841 tcataatgaa aataaatgta gtgttgaagg gagataaacg tgaattttta tagatttgta
     3901 ataaatattt ttaagggttt ttctaaaata ttttttaaat atgaagttat aggtgcagag
     3961 aatattccag atagaggaaa tatagtaata gcatcaaatc ataaatcgaa tcttgaccct
     4021 atattcttgg ctgctgccat agaaaatagg gaaatagctg caattgcaaa gaaagaattg
     4081 tttaaagtaa aaccattggg atttatatta aaaaaattgc atgttatgcc tataaataga
     4141 gaaaaaccag atgtatctac aataaaaact attttaaggt cagttagaga tggttatgta
     4201 ttaggaatat ttccagaggg tactagaata aaaggagatt cttttggtaa ggctaaggca
     4261 ggtctttctg tatttacaat aaaaagtaaa tctaaagttg ttccagtatc aataatatct
     4321 aaatataaac tttttagtaa agtaattgta tatattggag aaccaatatc atttgaagaa
     4381 cattttaagg aaaaattgag taatgatgac catgaaagga tatcacaaga gattttagaa
     4441 gtgataaaac aaaattactt taaatattca aaataagggg gtaaagttat gaacataaaa
     4501 atagcaaaaa atgctggctt ttgttttgga gtaaaaagag caatgaaaat ggcatgggat
     4561 gaagttgaaa aaaatgattc tggcatatat gctttaggtc ctcttattca taacaagcaa
     4621 gcagtagcaa aatatgaaga aaaaggtctt aagactgtga atgaaattga tacaatacca
     4681 aatcatgaaa atatgataat aaggtctcat ggagttcctg aaaatatata taaggaagcc
     4741 aaagataaaa aattaaaaat tgtggatact acatgtccat ttgtaaagaa aatacataca
     4801 gtagtaagtg aatatcataa taaaggctat gaaataatag ttattggaga tatgaagcat
     4861 ccagaagtta taggtataaa tggatggtgt gaaaattcag ctataataat aaagacctta
     4921 gaacaaatgg aaaatatgga atttgataac tccaaaaaat attgtcttgt tgcacagact
     4981 acaataaatc cagagttgta tataagtata gttaataaac tatcagataa attagaagaa
     5041 atagtattta atgatacaat ttgttcagct acaaaaacaa gacaagaatc agctaaagag
     5101 ttagctaaag aagttgattg tatgatagtt ataggaggta aacacagttc aaatactcaa
     5161 aagttagtaa aggtttgtga agacttagta ccaacttttg caatagagac taaagatgaa
     5221 ttggatgtaa atacgcttaa aaaatataaa aatttgggta ttacagcagg ggcatctaca
     5281 cctaattgga taatagaaga agttgtaaca ttccttgaaa atttataatt tgataggtaa
     5341 taaaaatagg tggacattgt tataatttat cataatatcc acctttgatt tcatattaca
     5401 tgtggtaaat agataaccta atatcaaaaa gtgtgtatct taagatgaaa aactaatagt
     5461 ataagatgcg cactttttaa tattagaaat tcaaaagaaa tattgatatt gattatcaat
     5521 agaaaataaa atataatata attgttgcaa aattagtcta ggaggtaaat taatggaaat
     5581 gttgatatcc gcttctgaag aggcgttttt acatgtaggt tctatgattg gattttttat
     5641 tttgttattt ggatatatta attataaaac tagtggaaat tttactaata tcatatcaaa
     5701 aaacagaaaa tttcaaccat taataggtgc tttaattgga gctataccag gttgtggcgg
     5761 aagcttggca ataatgccat tgtatataaa tggaaaatta agctttggag caataattgc
     5821 aagtttaata gctagtatgg gagatgcagc atttgtactt atttcatcaa atattaaaat
     5881 gtattttttt gtcactatag ttagtacaat tacaggaata ataactggac aattagtgga
     5941 ttactttaaa ctagaagaaa aattagggtt aaaaaaccgt agaaaatcag ataaatatga
     6001 tataagtaaa aataactcta aagaaaataa agaacaacat aatcatgatg aaataatttt
     6061 agacactcta gctaaatctc atggaaatac aaatagactt gcatttataa taacacatgg
     6121 aaagggatat aaaatttata taggaattat agtaatcggt tttatattta tgtcacttgc
     6181 tcactctgga cttaatcttc ctataattga gaagttacat tcattggaag aagtaatagc
     6241 agtgattgga atattatttt caataattta tatgtggtgt tttaaaaagg tatttaaaaa
     6301 ttctaatcaa aaagaggaag aaaataaaaa gatttctttg cgagaaatgc ttatccattc
     6361 tgttggagaa atatcatttg taattacatg gatttttatt gcatatctta tttacgattt
     6421 gataatatta attttaggtg gagatgaata cttagttaaa ctagtattat caacaggtgt
     6481 aataagtgta tttataggtg caggtcttgg acttattcca ggttgtggga tacaaattgt
     6541 gcttatgtca ttttatttga agggaactat accacttggt gcagtgatag ccaactctat
     6601 ttctcaagat ggagatgcac ttttcccact tttagcaatg gataaaaaat cttctttatg
     6661 ggctatgatt attactacta taccagcaat acttgtaggt atgatagttt atgcattttt
     6721 aggttaaata taattacgaa taaagaagta ttaaaaaaat aataaagcac ataaatttat
     6781 ttataagaat agtgaagatt aaatataaaa ataaaaaatt caatatgaat taaattattg
     6841 cttaaatatt aatgagaaca tgggagataa tattattcct catgttctct ctatttaatt
     6901 aaaggaatta tggaacaaat ttcaagtgat actttctatc aaaactcata tataatatat
     6961 attaataaat taaactataa tacgtaatac agtcagtata ttgatataaa aaacttagga
     7021 ggggttataa aaatgggtaa tttaaaaaga caatgtgatg tttcaagtgg aagagaaaaa
     7081 gctgacattg tactaaaaaa tgggacaatc ataaatgtat ttacagaaga gttaataaca
     7141 ggagatgtag caatagtagg agacactatc gttggtattg gcgattacaa gggcaatgta
     7201 gaaattgatt gtagcaacaa atatatatca cctggcttta ttgatgcaca tatgcatatt
     7261 gaatctacaa tggtaatgcc aattgaatta tcgaaaaaat tattaaaatc aggtacgaca
     7321 actatcatag ccgacccaca tgagttggtc aatgtaaaag gagctagtgc aatagatttt
     7381 ttattagaat cgacaaaaga tataccactt aatgtatata ttatggtgcc ttcatccgta
     7441 cctgcaacaa gttttgaaac taatggagtt ggtaaattta gtgcaaaaga catggagagt
     7501 tatgtaaata atcctagaat tttaggttta ggagaggtaa tgtgttttaa tgatgttata
     7561 aattctgaaa atgaaatctt ggataaacta gagcttttta aaaataaagt tgtagatgga
     7621 catgcaccta atataaatgg taaatcactt cagacatatg tatgtgcagg aatagaaaat
     7681 gaccatgaat gtataacttt tgatgaagta tatgaaaaat tgagagcagg attaaaaatt
     7741 ttaataagag aaggaagcgc agcaaaaaat ttaaagtcta tagtaagtgg tatgctaaag
     7801 cataacttgc caattgaaga atttatgttt tgcacagatg ataagcactt agatgatata
     7861 gaaaaacaag gtcacataag atggaatata aaatgtgcga ttgatttagg tatggaacct
     7921 gttagggcta taaaagttgc aacttataat tctgcaaaag catatgggtt aaggaaaatt
     7981 ggagcaatag gtgcgggtta taaggcagat attgttgtat tgaatgattt agacaaaatg
     8041 gaagtggata gtgtatataa agatggtaat ttggtaaacg aagagatgtt ttctaattac
     8101 aattatgaga ttaaagataa agaattgctt aatacagtca agtttaaata tattaataaa
     8161 gaaaaaatac agttaaaagt aagtgaaaaa aattatgtaa tggagattgt accttatcaa
     8221 attttgacaa ataagttata tgaatcttta ccatgtgcag atggatattt tgttccaaat
     8281 aaagagtatt caaaactttg tgttgttgag agacatagaa tgactggaaa tgtagcaatt
     8341 gctccactaa aaggatttgg cataaaaaat ggagcaattg ctactactgt ggcccatgat
     8401 tctcataata ttatagttgc aggggataat gatgatgata ttctagtagc tataaattac
     8461 ttaaaggaaa tacaaggtgg ttatgtaatt gtatcaaatg gaaaagttct tgcacaccta
     8521 agtcttcaag tagctggatt aattagtact tttacagctg aagaagtaca agaaattact
     8581 gataatatgt tggagatagc aagaaaaatg ggagttccag agtatgtaga cccttttatt
     8641 acactttctt ttatggcact tccagttgtt ccacaaataa gacttacaga tttaggtcta
     8701 tttgatgttg aggaatttaa atttatatag ataatataaa agtaataata aatgaggctt
     8761 tctcaaaata gggataagtc tctttttatt gttgaaatga tggaaatata tttgatttca
     8821 tacaaaaaag agcatctcat gaactaaaaa ttttattttt agatatcctt attttaatta
     8881 atctatcatt taaccttgtt ttaagcatag atatcttaat aaaactattt tcagtctatt
     8941 ttaacatata aatacatgaa aatta
//
LOCUS       DAEPXW010000125         8804 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.129, whole genome shotgun sequence.
ACCESSION   DAEPXW010000125 DAEPXW010000000
VERSION     DAEPXW010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.129"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            72..1265
                     /locus_tag="KRM55_003244"
     CDS             72..1265
                     /locus_tag="KRM55_003244"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBH1595451.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            1471..2589
                     /locus_tag="KRM55_003245"
     CDS             1471..2589
                     /locus_tag="KRM55_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBH1595452.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVREFARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNK
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            2720..2965
                     /locus_tag="KRM55_003246"
     CDS             2720..2965
                     /locus_tag="KRM55_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBH1595453.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            2952..3698
                     /locus_tag="KRM55_003247"
     CDS             2952..3698
                     /locus_tag="KRM55_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1595454.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            3981..4856
                     /gene="hslO"
                     /locus_tag="KRM55_003248"
     CDS             3981..4856
                     /gene="hslO"
                     /locus_tag="KRM55_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBH1595455.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            5247..6047
                     /locus_tag="KRM55_003249"
     CDS             5247..6047
                     /locus_tag="KRM55_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH1595456.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            6575..>8804
                     /locus_tag="KRM55_003250"
     CDS             6575..>8804
                     /locus_tag="KRM55_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012580989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1595457.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LKEGAILLSGFGVGSWHWNIFAESGFFDINKKICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAK"
BASE COUNT         3465 a          875 c         1737 g         2727 t
ORIGIN      
        1 tttaggttat aataaatatg tgcgtaaaat ctaacaataa gcaataatac cgtaaattta
       61 ggaggaataa tatggatact ttaaaggaac tttttaaaat aggaagtgga ccttcaagtt
      121 ctcatactat gggaccacaa agagcagcag agagatttaa gaatgaaaac ccagatgcag
      181 aaagttttag agcaatatta tatggtagtt tggcagccac agggaaaggt catttaactg
      241 actatataat tgaaaaaact atagcaccta aaaaagtcga aattgtttgg gaagaagata
      301 ttataaaaga ttttcaccca aatgggatga agtttgaagc tttagataaa gataaaaatg
      361 taacagctga atggactgta tattctgtag gtggagggac tatagcagaa gaaggtcaaa
      421 gaaacagtaa aagcaatagt atatatcact tagatactat ggatgagata gtaaaatggt
      481 gcaaagaaaa taataagact ttggtagatt ttgtgttgga atgtgaacca aaagacataa
      541 aagattatat aaaaactata aaagatgcta tgagaaaatc tattgatgat ggactaagta
      601 cagatgaaat aataccaggc aagttattat taaaaagaag agcaagtaca ttttataatg
      661 catataaaaa agataagagc ttctcaacac ttgtatatgc atatgcacta gcagcttcag
      721 agcaaaacgc ttctggtaat ataatagtta cagcaccaac ttgtggttct gctggagtaa
      781 taccaggaat attctttgca atgcaggatt tctataatta tgatgacgaa aaaataattg
      841 aagcactact tgtagctgga ataataggta atataataaa aactaacgct tcaatatctg
      901 gagcagaggt agggtgtcaa ggtgaagttg gagccgcttg ttctatggca gcagcagcag
      961 tagcatactt aaaaggtgga actatagacc atattgaata tgcggcagaa atagcacttg
     1021 aacatcattt aggaatgact tgtgaccctg tatatggata tgttcaaatt ccatgtatag
     1081 aaagaaatgc aatggcagct caaagagctt atgatgcagc taattatgca ttattaactg
     1141 atggctcaca ttctgtctcc ttagaccaag ttgttgaaac aatgaaagaa actggtatag
     1201 atatgatgga taagtacaaa gaaacagcta agggtggact tgctaaacat ttcttctctt
     1261 gctaaaaata aaattttcca ataataattc ctctgttttg atttatgaaa caggggaatt
     1321 attattaatg gtgaattatt taataatgca aaatattttt atattcaatt tagcttttta
     1381 tttttaatta gtataacatg ctatataata ttttaattat aaagaaatat agaaatattt
     1441 tttaataaat tagaaattgg aggagattac atgagagagg catcatattt acaagaacaa
     1501 ctttataaac ataggaagtc attaaatcct attgcagaga ttgggagaaa agagtataag
     1561 acttcaaaat atataagaga ttatcttgat aaattaggaa ttgagtatga agtttattta
     1621 gaaacaggta tagtaggtgt aatagaaggt aaaagaccta aaaaagatat tgcttttaga
     1681 gctgacatag atggtcttca tagtgaagaa ggggtaaaac atttatgtgg tcatgatgga
     1741 catgctacta tattacttgg attaattgag tatttaaatg ataataaaga agacttaaat
     1801 gataatatag tatttatatt ccaaccggca gaagaaggtc ctgggggagc aaaagcttta
     1861 atagatgaag gagtgcttag aaaatacaat attgatgaaa tatatggtct tcatatatat
     1921 ccagagttac cagaaggtta tgtaggtaca agagagggct attttatggc tcaaatagga
     1981 gatattgaca tagaaatagt gtctaaaagt ggacatggag ctatgccaca aaatggtatt
     2041 gatggtatag tgatagcttc aaactttgta agctcacttc aaactatagt gtctagaaat
     2101 ataagcccaa tagacaatgc agtgttgact attggcagaa ttgaaggggg agctagaaga
     2161 aatataatag ctgaaaatat aaagatggaa ggtactatga gatgtttcag cccagaagtg
     2221 tatgagaaaa tgaagcttag agttagagaa tttgctagag ggtttgaatt ggcttataac
     2281 tgtaaggtta atataaatat tatagatgat tatattgctg ttaaaaatga caaggatttg
     2341 tatcaagagt ttgtagaggc tattggaagt gatactgttg tagagttaga gccacttatg
     2401 atatcagaag atttttctta ttatcaaaaa gaagttccag gattattttt tatgttgggt
     2461 tcaagaaaca aagaaaaagg atttgtaaat ggtcttcata atataaactt taattttgat
     2521 gaaaagatat gtgtaaatgc attgaatgtt tattcaaaat tattaaaata caaagaagca
     2581 atagattagg aagataagtt ataaagatta aaaagcataa atacctaaat ttaaaaaaag
     2641 tgtattaata aatacccctt acatatttgt ataaatttat tttaattgac aaaaatacaa
     2701 ataagaaggg gtgatttttt tgaaagaaaa agtacaaaga gaaaagaaga taactaatgg
     2761 caagaatact aaaatattga caaatgatga tataatgaaa tatgagatag cctcagaact
     2821 aggtcttatg gataaagttg gtgaacgtgg atgggcagga cttacagcta aggaagcagg
     2881 aagaattgga ggtatgctta catcacgcaa aaagaggctt aaaaagattg tggaggagca
     2941 gaataaaaag gatgagtcaa tatagtgatt ttgcgtttgt atatgatgaa cttatgaatg
     3001 aagttgatta taatggttgg gttaaatata tagaagatat aatagatagt gaaggtgtaa
     3061 aagtaaaaaa tatattggaa ttggcatgtg gcacgggtaa tcttacaatt ccattgacta
     3121 aaaaaaatta cgatatagct ggtatagata tatctgatga gatgcttagt gtagcaagag
     3181 aaaaggcaga aaaagaagga gtagaattag ttttacttca acaagatata tcagagcttg
     3241 attttgaaat atctgatttg gactgtgtac tttgtgcttg tgatggattt aattatataa
     3301 cttatgatga tgatttggaa aatgtatttt caaagacata tgaattatta aagaaagatg
     3361 gaatattcat atttgatata agttcttttt ataaattagc caacatattg ggaaataaca
     3421 tgtatggaga aaatagagaa gatatagcgt atatgtggca aaattacttt gatgaagaag
     3481 agaatctaat tgaaatggaa cttacattct ttattaaaga tgaatgtgga aagtttgaaa
     3541 gatttgaaga gatacaccaa caaagagcat atactgaaga tgagatagtt gatatgcttg
     3601 aaaaatctgg atttaaggat ataaaatatt atggggattt tacatttgac aaacctagtg
     3661 aagaaagtca aagaatcttc tttgtatgta aaaaataaga tattcttgac tatataagat
     3721 aattattaaa aataaccatg atataaaaat atagaaaatg cagttttata gattaaaagt
     3781 aaagtgatga tactttatga cttttatttt ttaataatta taaagttcta tagataaaaa
     3841 ttaaaatata ataactattg cttagtaaaa ttaaaataaa atgggttttg cccaaggtta
     3901 agatagataa gtatttatag ataaattaag gtagtaatat aataaaaata agacaattaa
     3961 cgggacatgg aggaatatta atgagagatt atgtactaag agcgacatca ggaaatggtc
     4021 aagttagagc atttgtcgca actactagaa atacagtaga agaagctaga agattacatg
     4081 aaactacaaa agtagcaaca gcagcacttg gaagaacatt aacagccaca tctataatgg
     4141 gattaatgat gaaaaatgat agtgataaat tgactgtaat aataaaaggt ggaggtccaa
     4201 ttggaactat tatcgccaca tcagactcta agggaatggt aaaaggatat gtaggaaatc
     4261 cacaagtaga ggttgaagac tatccaaatg gaaagttaaa tgtagcagca gcagtaggta
     4321 cagaaggtgt tgtaaaagtt ataaaagact taggtcttag agaaccatat aatgggactt
     4381 atccattggt aagtggagaa attgcagaag actttactta ttattttgct gtatcagagc
     4441 agactccatc agtagtagct ttaggtgttc ttacaaaaga agatgaagta gagtttgctg
     4501 gaggatttat agttcaatta atgccagatg cagaagaaga gactattgct aagttagagg
     4561 aaaatgtagc taaattacct tctataacta acatgttaaa agaaggaaaa tcaccagagg
     4621 atatattaaa tattgttttg gatggtttgg aacctaaaat acttgatacc tgtgaagttg
     4681 ggtttatgtg tgaatgttca aaagaaagag taaaaactgc tttggttgca attggtaaaa
     4741 aatcattggc tcaaataata gaagaagata aaaaagcaga agttggttgc cagttctgta
     4801 ataagaagta tatgtatagt gaagaagagt tgcttgaaat tttaaaggaa atgtagacta
     4861 taaaaatagt tgtattgata taagtaatgt tatagtgata tagtaaagtc gtattgatat
     4921 agtaattaaa gtataattta ttaataatag acatatttat attaaaaaat aagtttaata
     4981 aatttttaag cttaataaat tttaagaatt aagaagcttt ctggctgtaa tgtttgcaat
     5041 gttgcagtta gaaggctttt ttattttatt atagttcgtg tcaaagattg tatgaaacaa
     5101 taaaatattg taaaataatt tgtatattta gacctgattg acacaaaggt ttataagata
     5161 tttgagttga ttatacgaaa ttctatgaag tagtaaccct gtgactttaa tcatgggagg
     5221 ttcagaagaa ggagaaaatt ttaaatatgg aaagtaaaac gaagtacata ggaataagta
     5281 tattaatatt attgatgata tttttaattg caaaaaattt taacggaaaa cttgaaatac
     5341 ctattcctga gagtaatagt agaaaattta aatcagcagc agtgttttat cctcaacatc
     5401 aagatgatga ggttttatgg ggaggaagtg ccattgtaga tgctataaaa cagtgtggtg
     5461 ttgataatgt atatgtggta ttagtatcag atggttctgg agttaacgtt ttcaaagcta
     5521 acacaaaatt tagaaattta actaggaagc aaaaggaaga gcttagaaat aacgagttta
     5581 aatcagcttt gagagagctt ggagtgaaac ctcaaaatgt gattatactt gcagatatag
     5641 ataaaaagga aggcacacat tatgaattaa tggaaaagac tatattggat tttgaacata
     5701 agtttaaagg caatgtgacc catatagccc atcactataa gtatgatgac catataatgc
     5761 atagaaagaa tggggaagtt ttaaagaaac ttaaacgtga gggtaagata aaagatgact
     5821 tgtattttgt taagccaaaa tatgtaaagt atataccaag aaatgaaaga gctatctata
     5881 aagcaatgga ttttgatgac tacaataagg ttaagagtgc ttgttatgaa tataaggttg
     5941 taaattcaaa gcgtaaaatg tatggtatag gatatatttc ggcacatagt tattttgaac
     6001 atcttctaaa tgaccctgaa cttacgtctg tattaagtga agattaattt cttataagta
     6061 gtaagttatg tttgataagt tgattggaat tttctatagt tttgaaggta ttggaaattt
     6121 agttttattt aaagatttaa agatagaggt ttttaatgtt taaaatttta aagttaagtt
     6181 gagtaattgt atagaattat ttgtgaaaga agaaacagtg taaaacatag tatcttattt
     6241 atggttttaa aatcataggc aagatacttt ttttatgtaa ctaataccat tttgagatta
     6301 ttaacttaag aattttatat aatttaacac tcatatataa tgatgatatt taggtagaat
     6361 agatgtaatt atgcttaaat aaaataactg tattttttat aaaaatccaa accctacact
     6421 atactaccag ataaaatcta catgctataa tttgacctgt gtttataaaa aaaggagtaa
     6481 tctaataaaa tagtatttca cttatgtata actaacaact attattacga ttttctctaa
     6541 ataatttaaa gaaaaataat gcaggaggta aaatatgaac aatgaattta taattttaaa
     6601 aggttgcaaa gagaacaatt tgaacaatat ttccttaaaa ataccaaaaa gaaaaataac
     6661 catattcaca ggggtgtcgg gttctggaaa gtcatctatt gtatttgaga caattgcaaa
     6721 agaatcacaa cgccaactaa atgaaaggtt tagtacattt gtaagaagtt ttttacctaa
     6781 gtatggagag gttaaagctg attgtataga aaatctgtca acaccaatta tcatagacca
     6841 aagtagactt ggtggaaatt caaggtcaac cctaggtact attacagatg taaattcctt
     6901 tttaagagct ttatattcaa ggtttggtag tgagtatata ggtaatgcca atatgttttc
     6961 ttttaataat attgatggta tgtgcccaca ctgtcatggg cttggaaaaa agctagttcc
     7021 taatatgaac caaattcttg atatgaataa atcattaaag gaaggtgcta tattgctttc
     7081 agggtttgga gtgggttctt ggcattggaa tatattcgct gaatcaggat tttttgatat
     7141 taataagaag atatgtgatt attcagaagt agaattggaa aagtttttgc atggtaaagc
     7201 agaaaagatt aagatagaaa atgctggtca aactaacatg acatatgagg gattaatggt
     7261 taaatttaat cgcctatact taagtagaga gggagaaata tctgaagcta ctaagaaaaa
     7321 attgagtaaa cttcttatag aagatagatg tcctatatgt gatggaagaa gacttaatga
     7381 aagagtatat aggtctttaa ttaatggtta taatatagca gatttaacta gtatgcaaat
     7441 tgatgaattg gctgaagtta ttaaaagtat agatgagcca gaagcacaac ctttaattaa
     7501 aggaataata gaaaagttaa acagtatcat agatataggt cttggatatt taacactaga
     7561 tagagagaca tcttctctat caggagggga atctcagcgt ataaagatgg ttaagtattt
     7621 aaatagtaat cttgttgatt taatgtatat ttttgatgaa ccaagtgtag gacttcatcc
     7681 aaaagatgtg tataaattaa ataatctttt aaaaaaattg cgtgataaag ggaatacaat
     7741 tatagttgtt gaacatgacc cagatgttat taagattgca gaccatattg tagatgtagg
     7801 accaaaggca ggtaagtatg gtggagaagt tgtgtatgaa ggcagttatg aaaatctact
     7861 tacaagtggt actttgacag ggaatgcttt aagtaaattt cttcctatta aagaaagtgt
     7921 aagagaacat agtggatatt tagaagttaa aaattgtaat aaaaacaatt taaaaaatgt
     7981 atcgattaag atacctaaag gtgtattgac tctagttact ggagtagcag gagcaggtaa
     8041 aagtacgttg attaaggatg aatttttaaa gcaaaatcct agtgctgtac ttatagacca
     8101 aagccctgtt tcagcaaatt caaggtcgag tttggcaaca tatagtggaa ttatgaacaa
     8161 cataagaagc atattttcaa aaacaaatgg cgtaaatgct tctttattca gttcaaattc
     8221 agaaggagct tgtgataact gtaagggttc tggaatagta gaaatgaatc ttgcttttat
     8281 ggagagtata aagagtacct gcaatgtttg tgaaggtaaa aaatttaaaa aagaagtttt
     8341 agaatatagg tttcaaggga agaatataat tgaagttctt gaaatgtctg ttttagaggc
     8401 aattgagttt tttaatttaa aacagattaa aacgaaatta caatgtattg aaaaaatggg
     8461 tattggatac cttactttag gacaaactct tgatactttg tctggaggag agtgtcaaag
     8521 attaaagctt gctagtgaat taaataagga aagttcagtg tatatattag atgaaccaac
     8581 aacaggtctt catatggctg atattgagaa ttttataagt ataattgaag agattgtaga
     8641 taatggaaat acggtcataa taattgaaca caatatagat gtaattaaaa gagctgattg
     8701 gattattgag ctgggacctg aaggaggaac aaaaggcggg agagtaatat ttgaaggtat
     8761 tccaaaacaa ttatgtaaca ataaaatatc attaacagca aaat
//
LOCUS       DAEPXW010000126         8799 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.130, whole genome shotgun sequence.
ACCESSION   DAEPXW010000126 DAEPXW010000000
VERSION     DAEPXW010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8799
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.130"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            108..1709
                     /locus_tag="KRM55_003251"
     CDS             108..1709
                     /locus_tag="KRM55_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBH1595458.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNLLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVIQQCINASNSNGQPPTITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLTIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            1928..3517
                     /locus_tag="KRM55_003252"
     CDS             1928..3517
                     /locus_tag="KRM55_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp12"
                     /protein_id="HBH1595459.1"
                     /translation="MKVNKRVLSIGLTISLIMAGVPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGTVKAPILLSQRNSIPSDTEKMLKDVKKV
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGNDRIETSYLIAKEIASIKPIDKVFITNGY
                     TGEADAMSASSVASRDGAPIILTNGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNIVAK
                     DSNGNDLTPELIGNINTDKVGKYKVTIKATDIGGKTTSISVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYSLVNSYRKEKGKEALQVSKNLEGLSNSWSKYMADKGQFSHVIDGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDAREVANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILPNGEVYATQEFLNK"
     gene            3742..5961
                     /gene="slpA"
                     /locus_tag="KRM55_003253"
     CDS             3742..5961
                     /gene="slpA"
                     /locus_tag="KRM55_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBH1595460.1"
                     /translation="MNKKNIAIAMSGLTVLASAAPVFAANEFVADSNYTVVQGKYQKV
                     ITGLQDALKDGKISKIDVIFDGSSIGEVEPGGDPAAAAVKLKNLVDDKLDNLGDGKYV
                     QFNVTYSTTSVITKAELKNYYNKLDKEKILVSNEPTTTVNGLIKADQSPNQANGVAAD
                     EPLKLSDVITLSYDDEAGTLTATQNATNVASNKVKDLKFGTATTGSYTAGKEITVPAT
                     ATITAGTSTTADFNLDDPSKAFKFDPSSAEISGFVTGQAGQTLKASIKIINAKEESID
                     VDSSSHRTAEDLAEKYVFEPADVNAAYEALNDLYKEGLTSDLITQDGGKYQVVLFAQG
                     KRLTTKGATGTLADENSPLKVTIKADKVKDLKDYVEDLKNANNGYSNSVVVAGEDRIE
                     TAIELSSKYYNSDDDNAITKDPVNNVVLVGSQAVVDGLVASPLASEKRAPLLLTSAGK
                     LDSSVKAELKRVMDLKSTTGVNTSKKVYLAGGVNSISKDVENELKDMGLKVTRLSGDD
                     RYETSLAIADEIGLDNDKAFVVGGTGLADAMSIAPVASQLRNSNGELDLKGDATPIVV
                     VDGKAKDINSEVKDFLDDSQVDIIGGVNSVSKEVMEAIDDATGKSPERYSGEDRQATN
                     AKVIKEDDFFKNGEVTNFFVAKDGSTKEDQLVDALAGAAIAGNFGVTVDNEGNPTVVG
                     KKASPAPIVLATDSLSSDQNVAISKAVNDDANTKNLVQVGKGIATSVISKIKDLLDM"
     gene            6208..8553
                     /gene="secA"
                     /locus_tag="KRM55_003254"
     CDS             6208..8553
                     /gene="secA"
                     /locus_tag="KRM55_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH1595461.1"
                     /translation="MSVIDAILDKADEQEIKKLNVIVDKIDALEESMKKLSDEELKDM
                     TAIFKDRLKKGETLDDILPEAFAVVREVSKRKLGMRQYRVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYESLDMTVGVIISNQD
                     PSIRKEQYKCDITYGTNSEFGFDYLRDNMVPDLSHKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGDGDEDLKLYELANSFVKTVKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNKPVIRADLHDKVFKTEEEKYSAVVEEIIRIHKTRQPILVGTVSVEKSEKLSKMLKK
                     QGIKHQVLNAKQHDKEAEIISKAGKLNAITIATNMAGRGTDISLGAGDKEEEQEVKDL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIQEDIQKMVKDIIQEAGETYLIGRKRDYYGYFKHLYSTFMPADTLLIPGVDKKS
                     VQEIIDSTYEISKRVYDLKKMMLGIDKVAELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATVQYLYKFN"
BASE COUNT         3617 a          966 c         1684 g         2532 t
ORIGIN      
        1 gagatatatt catatcatat atactctata atatatggaa aataaagaga aaataaatgg
       61 aaaataatca caatataaat ataaaatata aaaatcatca gggggatatg aaaatgaaca
      121 aaaaaatatt atcattaggt ctagcagtat cattaatctt agtaaacttc aaaagtgtaa
      181 atgcatcatc agtagtagaa aaaatatacg gtaaagatag atatgaaaca gcagcaaaga
      241 tagctgataa acagacttat gaaacagtaa ttttagtaaa tacagaaaaa tcacttgcag
      301 atggattaag tgcaagtgga ttatcaggag ctacaaaagc tccaatacta tttacacaac
      361 aaaataagat accagcagac acaaatagat gtctaaaaaa tatcaaaaaa gcatatataa
      421 taggtacaga agatactata agtaaatcag tagaaaaaga actagattct aagaatatag
      481 aagtcaaaag aattggtgga gaagatagac taaaaacaag ctatttaata gctaaagaaa
      541 tagcaactat aaaaaaagtg gataaagtac tattaactaa tgcatatagt ggagaagcag
      601 atgcaatgag tgtatcatca gtagctacta gagatggagc tccaatcata cttacagatg
      661 gaaagagtgt gccttttgat gtaaaaaata ttcaatcata ttgtataggt tcagaggaga
      721 taatgagtaa tcttctagtt aaaaatacaa actcagtaag aatagaagga actgaccgat
      781 ttgaaactaa caaaaacgta atagactact tttttaatag tgcagatgga ttctatgtat
      841 cagatggata ccaattagta gatgcaatag cagccgcacc acttactaaa aactctccaa
      901 tggtactagt aaatgatgga agcgataaaa ctgtattaga aggagctaag aatataacct
      961 ctgtaggtga aatagatgag aaggtaatac aacagtgtat aaatgcttca aattcaaatg
     1021 gacaaccccc aacaattaca gttgggagta cagaggtata taagggtgaa aagtttgaca
     1081 ctggcaagtt aaatatagta gctaaagata acacagggaa ggtattaaca atagaagttg
     1141 atgggtttat agatacaaat agagtaggta catacatatt gacattaaaa gctacagacg
     1201 aatggggaaa aagcacagga aaaagagtag aaataaaagt gttggatgac aaatctcatg
     1261 attacaacag cccagaattt aaaaaaatgg tatctactga aatgtataac ttaatcaatt
     1321 cctatagaaa agaaaaaggc aaagagcctt tggtagtgtc tagtaggcta gaaggtatgg
     1381 caaatgcatg gtctaagtat atgatggata aaaaagtatt tgcacattat atagatggaa
     1441 aaaatgctcc acaagtattt tctgagtttg gaatgagaag tgaggaaaat atagcatata
     1501 tttatataga ttctaagaac gttcaaacta cacaagatgc aaaagactta gcaaaggcta
     1561 tatttgaggt gtggaagaag tctccagagt acaatgcaaa catgcttagt gatgagttct
     1621 atagtactgg atttgggctt tatatattat ctgatggtca agtgcatgct actcaggagt
     1681 ttttaaatgg aaatgaaggt agcttgtaaa aaattccata aatcttgttt ttttgttaat
     1741 ttactgatat tataaaatga aaatcacatc taaagtactt tttgtaatct gttttgttat
     1801 tgctttacag gttatggtat tttaggtgtt ttttgtttta gtagtttata gattttgagg
     1861 gaatcactac tgaggatgta atttatgatt agctgaatta tataaaaaaa ttagtaggag
     1921 gagtttgatg aaggtaaata agagagtatt atcaatagga ttgacaatat cattaataat
     1981 ggcaggagta ccaaatatca atgcactttc gagcatagaa aagatacaag ggaaagatag
     2041 atatgagaca gctgccaaaa ttgcacagaa acaaacatat gaaaatgtag tattagtaaa
     2101 tacagataat acactagctg atggattaag tgcaagtgga ttagcaggaa cagttaaagc
     2161 acctatatta ttatcacaaa gaaacagtat accatcagac acagaaaaaa tgttaaaaga
     2221 tgtaaagaag gtttatataa taggaactga agattcaata ggaaaatcag ttgaaaatga
     2281 attaaagcaa aaaggaatag aagttaaaag aataggtggt aatgatagaa ttgaaacaag
     2341 ttatcttata gcaaaagaaa tagcttcaat aaaacctata gataaggttt ttataactaa
     2401 tggttataca ggtgaagcag atgctatgag tgcgtcatca gtagcatcaa gagatggagc
     2461 acctataatt ttaactaatg gtaaaaatgt tccatttgag aaaaaagaag gtgttcaatg
     2521 ctatgctctt ggttcagagg agataataag taatgattta gttaaaaaaa ctaatgcagt
     2581 tagattagct ggagaagata gatttgagac taataaaaaa gttataaaac atttttatag
     2641 ttcagcaaaa gaattttatc tttctaaagg ttatcaatta gtagatgcag ttgcgggttc
     2701 ttctatagca aaaaatgcac ctattgtatt ggttgatgga aatagtgata agtctgttct
     2761 tagaagtgct gataaaatca cagcactagg aggaatagat gaaaagacac tagaacaatg
     2821 tttaagtgca tcatcactgg atgcaagtgc accaacaata actgttggaa atttaaatat
     2881 ttatcaaggt gataagtttg atataagtaa actgaatatc gtagcaaagg atagcaatgg
     2941 taatgatttg acaccagagc ttataggaaa tattaatact gataaggttg gtaaatacaa
     3001 agttactata aaagctactg atattggtgg aaagactacc tcaataagtg tagaagtaaa
     3061 tgtacttgaa tataagacta atgatatgaa tagtagtgag tttaaaagaa tggtttctag
     3121 tgaaatgtat agtttggtaa attcatatag aaaagaaaaa gggaaagaag cattacaagt
     3181 ttctaaaaac ttagaagggc tttctaattc ctggtctaag tacatggcag ataaaggcca
     3241 gttttcacat gtaatagatg gtaagaagtc tgttgaggta tttactggat atgggttgag
     3301 aagtgaagaa aatatagctt ttgtaccact tgttacaaag agcacttata cgacaaagga
     3361 tgctagagaa gtagcaaatg taatatttac agtttggaaa aaatcggata aatataatga
     3421 aaatatgcta aacagtgatt ttgtatatac tgggtttgga ttgtatatat tgcctaatgg
     3481 agaagtgtat gctactcaag aatttttaaa taagtaattt aaataagtaa aatcaaattt
     3541 tttaagttat taaatattgg agtttaaggg tataaaaact catatgcttg ggaaaaataa
     3601 taatttcaaa aaaatgactt gcaaaaagaa taaaaatgga ttattataga gatgtgagaa
     3661 atattaggaa tatatggatg attattctat gtacataata aagagatgta atttaatata
     3721 atgttgggag gaatttaaga aatgaataag aaaaatatag caatagctat gtcaggttta
     3781 acagtattag cttcggctgc accagtattt gcagcaaatg aatttgttgc ggattctaat
     3841 tatactgtag ttcaaggaaa atatcaaaag gttataactg gtttacaaga tgctttgaaa
     3901 gatggtaaaa tatcaaaaat tgatgtaata tttgatggaa gttcaattgg agaagtagag
     3961 ccaggtggtg atcctgcagc tgcagctgtt aaattgaaaa atttagttga tgataaatta
     4021 gataatttag gcgatggaaa atatgttcaa tttaatgtta cttattctac tacgtctgta
     4081 ataactaaag cagaattaaa gaattattat aacaaattag ataaagaaaa aatacttgtg
     4141 agtaatgaac ctacaactac agtaaatgga cttattaaag cagaccaatc acctaatcaa
     4201 gctaatggag tagcagcaga tgaaccatta aaattatcag atgtaataac actttcttat
     4261 gatgatgaag ctggtacact tacggcaact caaaatgcta ctaatgtagc ttcaaataaa
     4321 gtaaaagact taaaatttgg tactgctact actggttcat atactgctgg taaagaaata
     4381 actgttccag ctactgcaac aataacagca ggaacaagta caacagcgga ctttaatctt
     4441 gatgatccat caaaagcatt taaatttgat ccatcaagcg ctgaaataag tggatttgtt
     4501 actggtcaag ctggtcaaac tttaaaagca agtataaaaa taataaatgc aaaagaagag
     4561 tctatagatg tagattcaag ttcacacaga acagctgaag atttagctga aaaatatgta
     4621 tttgagccag ctgatgttaa tgcagcttat gaggcattaa atgatttata taaagaagga
     4681 ttaacaagtg accttataac tcaagatggt ggaaaatatc aagttgtttt atttgctcaa
     4741 ggaaagagat taactactaa aggagcaact ggcactttag cagatgaaaa ttctcctctt
     4801 aaagtaacaa taaaagcaga taaagtaaaa gatttaaaag attatgttga agatttaaaa
     4861 aatgctaata atggatattc aaattctgtt gttgtagcag gtgaagatag aatagaaaca
     4921 gcaatagagt taagtagcaa atactataac tctgatgatg acaatgcaat aactaaagat
     4981 ccagttaaca atgttgtttt agttggttct caagctgtag ttgatgggct tgtagcttca
     5041 cctttagcat ctgaaaaaag agctccttta ctattaactt cagcaggaaa attagattca
     5101 agtgttaaag ctgagttgaa aagagtaatg gatttaaaat ctacaacagg tgtaaatact
     5161 tctaaaaaag tttacttagc tggtggagta aactctatat ctaaagatgt agaaaatgaa
     5221 ttaaaagata tgggacttaa agttacaaga ttatctggag atgatagata tgaaacttct
     5281 ttagctatag ctgatgaaat aggtcttgat aatgataaag cttttgtagt tggaggaaca
     5341 ggattagcgg atgctatgag tatagctcca gttgcttctc aattaagaaa ctcaaatgga
     5401 gaacttgact taaaaggtga tgcaactcca atagtagttg ttgatggaaa agctaaagat
     5461 ataaattctg aagtaaaaga tttcttagat gattcacaag ttgatataat aggtggtgta
     5521 aatagtgttt ctaaagaagt aatggaagca atagatgatg ctactggaaa atcacctgag
     5581 agatatagtg gagaagatag acaagcaaca aatgctaaag ttataaaaga agatgatttc
     5641 tttaaaaatg gagaagttac aaacttcttt gtagctaaag atggttcaac taaagaagat
     5701 caattagtag atgctttagc aggtgctgca attgctggta actttggtgt aacagtagat
     5761 aatgaaggaa atcctacagt tgttggtaaa aaagcttctc cagcaccaat tgttttagca
     5821 acagattctt tatcttctga tcaaaatgta gctataagta aagctgtaaa tgatgacgct
     5881 aatactaaga atctagttca agttggtaaa ggtatagcta cttcagttat aagtaaaata
     5941 aaagatttat tagatatgta atataagttt taataaaact ttaaatataa aaagacttct
     6001 cagatgagaa gtcttttttg tgaaaaaaat aaatacaaaa taaaatagag gctatttata
     6061 gcctctattt tatgtgagaa atactcaaat aaaaagatgt ttaatttatt taagtaaagt
     6121 cattatacta taaatcaaaa taattgtcta ctattatgga tttttaatgt ataatagtaa
     6181 ttggacaata gaaaaggagg tacttatatg tcagttatag atgcgatact tgacaaagca
     6241 gatgaacaag aaataaagaa attaaatgtt atagtagata aaatagatgc acttgaagag
     6301 agtatgaaaa aactatcaga tgaagaacta aaagacatga cagctatatt taaagataga
     6361 cttaaaaaag gtgaaacttt agatgatata cttccagaag catttgctgt agtaagagaa
     6421 gtatcaaaaa gaaaattagg aatgcgtcag tatagagtac aattaattgg tggtatagta
     6481 atacatcaag gaaaaatagc agagatgaaa actggtgaag gtaaaactct agttgaagta
     6541 gcaccagtat atttaaatgc ccttacaggt aagggtgtac atgtaatcac agtaaatgac
     6601 tatctggcag aacgtgataa ggagcttatg cgtccagttt atgaatctct tgatatgacg
     6661 gtaggagtaa ttatatctaa ccaagaccca agtataagaa aagaacaata taaatgtgat
     6721 ataacttatg gaacaaatag tgaatttgga tttgactatt taagagataa tatggtgcca
     6781 gatttatctc ataaagtaca aagagaacta aattttgcta tagtagatga agttgactca
     6841 atattaatag atgaagctag aaccccgctt attattgcag gagatggtga tgaagattta
     6901 aaactttatg agttagcaaa tagctttgta aaaactgtta aagaagaaga ctttgagatg
     6961 gacagaaaag ataaaactat agcattaaca gcaagtggta taagtaaagc tgagtcattt
     7021 tttggtataa caaaccttac tgatataaag aacatagaat tatatcatca tataaatcaa
     7081 gctttaagag gtcacaaact tatggaaaaa gatgttgact atgttatttc aaatggagaa
     7141 gtaatgatag ttgacgaatt tacaggaaga gtaatggatg gtagaagata tacagatgga
     7201 cttcaccaag ctatagaagc caaagaaggt gttgagataa agaatgaatc taaaactatg
     7261 gctactgtga cttatcaaaa tttcttcaga ctatatgaaa aactttctgg tatgactggt
     7321 actgcaaaga cagaagaagg agaatttgag tcaatctata aattaaatgt tgtccaaata
     7381 ccaactaata aaccagtgat tagagctgat ttacatgata aggtatttaa aacagaagaa
     7441 gaaaagtata gtgctgttgt agaagaaata ataaggatac ataagactag acagccaata
     7501 cttgtaggaa cagtttctgt tgaaaaatct gagaagctgt ctaaaatgct taaaaaacaa
     7561 ggtattaagc atcaagtatt aaatgctaaa caacatgata aagaggcaga gataatttct
     7621 aaagctggta aattaaatgc tataacgatt gctacaaata tggcaggtag aggaacagat
     7681 atttctctag gtgcaggaga taaagaagaa gaacaagaag ttaaagattt aggtggactt
     7741 tatgttatag gaacagaaag acacgaatca agaagaattg ataatcagct tagagggcgt
     7801 tctggtcgtc aaggagaccc aggtacatca agattctttg taagtcttga agatgatgta
     7861 ataaagcttt atggtggaaa aactatagaa aaacttatga agagaacaag ttcaaaggaa
     7921 aatacggcta ttgaaagtaa agcacttaca agagctatag aaagagcgca aaaaggtgta
     7981 gaaggtaaaa attttgaaat aagaaaaaat gttcttaaat atgatgatac tattaatgag
     8041 caaagaaaag ttatatataa tgaaagaaat aaagtgttaa atgatgaaga tatacaagaa
     8101 gatattcaaa aaatggttaa agacatcata caagaagcag gagaaactta tttaattgga
     8161 agaaaaagag attattatgg atattttaaa catttatata gtacatttat gccagcagat
     8221 acattactaa tacctggtgt agataaaaaa agtgtccaag agataattga tagcacatat
     8281 gaaatttcaa aaagagttta tgacttgaaa aagatgatgc ttggtattga taaggttgca
     8341 gagttagaaa aaacagtact tttaaaagtg gttgatcaat actggataga tcatatagat
     8401 gctatggaac agttaagaca gtatataggt cttaaatctt atgctcaaaa agacccattt
     8461 aaggaatatg ctttagaagg atatgacatg tttgaagctt taaataaaaa tataagggaa
     8521 gcaacagtac aatacttata taaatttaac taaaaaagtt catgtaattt ttattaaatg
     8581 aaaaataaaa tattttgatt ctttatattg taattacaat taaataatta aaaaatacaa
     8641 atgaaaaaga agctgaaaat cagcttcttt ttctgtgtga gaaatacgga aaaaagagat
     8701 gcttgaaatt tctttcttcc atttaatatt atactataaa gaagatgaaa agtctattag
     8761 ttataaactg gattattaaa aaaaattaca attttgtta
//
LOCUS       DAEPXW010000127         8723 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.131, whole genome shotgun sequence.
ACCESSION   DAEPXW010000127 DAEPXW010000000
VERSION     DAEPXW010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.131"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            75..842
                     /locus_tag="KRM55_003255"
     CDS             75..842
                     /locus_tag="KRM55_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HBH1595462.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKGFCLADTSEPNYELLYFPFTDNAPIPYF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     misc_binding    1060..1273
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1527..2561
                     /locus_tag="KRM55_003256"
     CDS             1527..2561
                     /locus_tag="KRM55_003256"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBH1595463.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            2602..3819
                     /gene="argJ"
                     /locus_tag="KRM55_003257"
     CDS             2602..3819
                     /gene="argJ"
                     /locus_tag="KRM55_003257"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBH1595464.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDLE
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            3834..4694
                     /gene="argB"
                     /locus_tag="KRM55_003258"
     CDS             3834..4694
                     /gene="argB"
                     /locus_tag="KRM55_003258"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBH1595465.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKETE"
     gene            4724..5911
                     /locus_tag="KRM55_003259"
     CDS             4724..5911
                     /locus_tag="KRM55_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBH1595466.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVILKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            6020..7042
                     /gene="argF"
                     /locus_tag="KRM55_003260"
     CDS             6020..7042
                     /gene="argF"
                     /locus_tag="KRM55_003260"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBH1595467.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            7169..7786
                     /locus_tag="KRM55_003261"
     CDS             7169..7786
                     /locus_tag="KRM55_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBH1595468.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(8006..8704)
                     /locus_tag="KRM55_003262"
     CDS             complement(8006..8704)
                     /locus_tag="KRM55_003262"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBH1595469.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHDLMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
BASE COUNT         3502 a          855 c         1574 g         2792 t
ORIGIN      
        1 ttattcaaaa tattaagata aaaatatata gaatatattt aaaaattatt atgcaattag
       61 aaaaggagat aagtatgcag attattgata taaatataaa taatattgac aatgaacata
      121 tatgttgttc aatttctgaa aaaaaaggag aaaattgtgt tttttctaaa aaagcttgga
      181 tgaaaaataa ttttgataaa ggtctagtct ttaaacgatt tgatgtaaga ggtaaagctt
      241 ttatagaata tattccagca gaaaatgcat ggtgtcctat tactgcggac aattatatat
      301 ttattaactg tttttggata tctggaaaat ttaagggtca aggatattct aatctattgc
      361 tacaagagtg tgttgatgat gcaaaatcaa aaggtaaata tggattagtt gtgctttcgt
      421 ctagtaaaaa aatgcctttt ttatctgatg ctaaatatct aaaatataag ggcttttgtt
      481 tagcagatac atcagaacca aattatgagc tattatattt tccttttact gataatgctc
      541 ctattccata ttttaagaat tgtgtaaaaa aaagaaaatt aaatgagaac ggtatagttt
      601 tatattacag taatcagtgt ccacatacgg aaaaatatgc tcctattttg aaaaaaattg
      661 caaattctag aggtattgat gtaaatctta taaaattcga aacagcaaaa gaagcacaaa
      721 atgctcctgc accatttact acatacagtc ttttttttaa tggtgaattt gtaaccaacg
      781 agatactttc tgagaaaaag attgagaagt ttttagatac caacattaaa aaatttaact
      841 aaaaagagat gtaaatattg tattttgaaa atatattatt ttataattta atatattttg
      901 gatgtttttt aaattgacga atgaaatata aaaattatat cgcaatttag atacaaaatg
      961 ctggaaatta accatataga aaatatttcc aaaaatttaa aaattatatt gacaaagtta
     1021 aaaaaataaa ctatcatata aaacaataag aaaataaatt gaaatcctgt gaaaaagaga
     1081 gtagcataaa gctagttgat agagagctgg gaatggtgga agcctagtaa cgaattttat
     1141 tgtgaataga gctttggagg agattaccag aagtaatagt atggtaattg gtgaatctcg
     1201 ccttaagaga ttagagtggg taagattatc ttatcaatta gagtggtaac gcgggtgtat
     1261 attcgtctct tggtctttga ccaagaggct tttttaattt taaatgtaca ttttgtagat
     1321 actttttaat ttgagtttta atgattattg taattttacc aataagagtg gtaccgcgga
     1381 aaatcgcctc ttagtattta taatgctaag gggttttttg ttttaattag agtattttaa
     1441 tctacgtatt atcaaatgat tatcatatag taaagtggaa agataggatt ttaagactat
     1501 ttgaatataa aaatggaggg aacaaaatga ataaaataaa agttggtatt attggtgcaa
     1561 ctggatatgt cggggcagag ttgattagat tattaatgaa tcatgataaa gtcgaagtga
     1621 cagcgatagg ttcaaattcg tatgttggaa aagatatagt tgatatatat ccaagtatag
     1681 gatataaaaa taacatgata tgtatagaaa atgaaaaagt tatagatatg tgtgatgttg
     1741 tatttacagc ccttccacat ggagttagtg aaaagtttgt aataaaagca attaaatcga
     1801 aaaagaaagt tatagattta ggtgctgact ttagaataaa agatgaagaa gtatatagta
     1861 aatggtatgg agtatctttt atagataaaa tcttacataa aaaagctgta tatggattaa
     1921 gtgaaatata caaagaagat ataaaagatg cagatataat tgcaaatcct ggatgttatc
     1981 caactagtat ttctttacca ttgatgccat tactaagttc taaattgata aaaaataata
     2041 atataataat tgattctaaa tcaggtctta caggtgctgg tagagaatta tcgattagta
     2101 gtcactttac ggaggttaat gaaaatatca ctgcatataa aatagggaaa cacagacata
     2161 ctccagaaat agaacaaaat ttaagtgaat cctgcaaaga aaaagtaagt gtagttttta
     2221 caccaaactt aatcccagta aataggggaa tcttatcaac tatatattgt acaaaagaag
     2281 ataatatttc tataaatgat atacatagga aattaactga ttattatgaa tttaaagaat
     2341 ttatagaaat tcttccatta gataaggtag cttctttaaa gaatgttaga ttctcaaata
     2401 aatgtgtaat atcattacat gaaaatggag atacattgat aatctgttca gctatagata
     2461 atatgattaa gggagcagca ggtcaagcta tacaaaacat gaatataata tttggtattg
     2521 aagaaaatac aggtttaaaa aatattgcac catcatttta gaaataaaaa atactaaact
     2581 catataatta ggaggataaa tatggagatt ataaagggtg gagttacagt ttcagaagga
     2641 ttttttgctt cagggattca ctgtggcttg agaaaaaata aagaaaaaag agatttagct
     2701 ttggtttatt cagatgtttt atgtgatgca gcagcagtag taactcaaaa taaagtaaag
     2761 ggcaatcctg tttatgttac acaggaacac attaaaaatg gaaaagcaca agctatcata
     2821 gtaaatagtg ctaatgctaa tacctttaat ggaaaagaag gacttataaa tgcttataaa
     2881 atggctaaat tcaccagtga taaattaaat attaaagaaa gtgatgtttt ggttgcatct
     2941 acaggtgtta taggaaagcc attaaatata gatttaatag aagaaaatat ggatgaatta
     3001 gtgaataatc taagtaaaca aggtcatatt ggagcaagag aagctattat gacaactgat
     3061 attataaaaa aagaaatagc agtagcaata atgtatggag ataaaaaaat aactattgga
     3121 ggtatggcaa aaggttctgg catgatacat cctaatatgg caacaacgtt aggatttata
     3181 actacagatg caaatattga tggagttttg ctaaaagaag ctttaaaaat tgctgttgac
     3241 aaaagtttta atagagttag tgtagatgga gatacaagta ctaatgatat ggtaatgatt
     3301 ctagcaaatg gaaaagcaaa aaatgataga ataaacaaaa aagatgaaca ttatcaagta
     3361 tttttgagtg cacttacata tgtctgtata gaacttgcta aacttgttgc aaaagatgga
     3421 gaaggatgta caaaactaat tgaatgctat ataaatggag cattaagtga agaacatgca
     3481 gtaaaattag caaaaacagt tatatcttct tcattagtaa agacagctgt atttggagct
     3541 gacgcaaatt ggggtagaat actgtgtgct ttaggttatg caggtgaaga aatagatctg
     3601 gaaaaagttg atattatttt tgagagtatg aaaggatata ttgaagtatg taaaaatgga
     3661 aatggattag attttaatga ggaaaaagca aaaaaaatcc ttgaagatga cgaaataagt
     3721 atattagtag atttaaatat gggcaatgcc agaggaaatg catggggatg tgatttaagc
     3781 tatgattatg taagaataaa tggaagttat agaaattagg aggatatact ttaatgatta
     3841 atatagaaaa agcaaataca cttatagaag ctttaccata tatagaaaaa catcagggaa
     3901 agactattgt agttaagtat ggtggaagtg caatgaaaaa agatggtcta aaagaatctg
     3961 ttatggaaga ccttgtgtta atgagttatg ttggaatcaa tatagtttta gtacatggtg
     4021 gaggggcaga aatcaataag atgctagcaa aagtggatat agaaagtaaa tttgtaaatg
     4081 gtcttagata tacagatgaa gagaccatgg aaattgtaaa aatggtactt gctggaaagg
     4141 ttaataaaga cttagtaaat aaaatacata caaaaggtgg aaaagcagta gggctttgtg
     4201 gaatagataa taatatgatt ttatgtgacc catataaaaa ttatgaactt ggatttgtag
     4261 gagaaatcaa aaaagtaaat gttgagctta tagaatcttg tctaaagtca ggttatattt
     4321 cagtaattgc aactataggt gttggagatg atggagagac ttataatata aatggtgaca
     4381 cagcagcttc tgctatagct aaagagttaa atgcagataa attgatactt cttacagatg
     4441 tccctggttt gttaagagag ccagatgaag aaaaatcatt aataacagaa gttatattag
     4501 aggatgttga taaattattt gaagaaggta taattactgg aggtatgata cctaaaatag
     4561 agggatgcgt agatgcctta aataacggag taaatagggt acatattttg gatggaagag
     4621 ttccacattc tataataaca gagctattta ctgatagtgg aataggtaca ttaataagaa
     4681 aagaaactga ataaaattat aagtttaaga ggggagaata agaatgaata acgacaatac
     4741 aatttcaaaa tggaatgaat attttataga tacatataac caacccaatt ttgtcataga
     4801 ttatggtgaa ggaagttgtt tttttgatac taatggcaat aaatatatag attttacaag
     4861 tggatatgga gtatcttctc ttgggtatag taatagtaat ttaaagaatg ctctaaaaga
     4921 gcaagtagat aaattattac atacttcaaa tttatatttt aatgagccag tgttgtattc
     4981 aggagagaaa ataattaatt caagtggaat ggctaaagta tatttttgta attctggaac
     5041 agaagcaaat gaaacagcat tcaaaatagc aagaaagtat agtagtgaca aatatggtaa
     5101 tggtagagga actatcataa gtttaaaaga ctcttttcat ggtagaacaa tgatgtcttt
     5161 aatggcaact ggtatggaca aataccataa gtatttttat cctcttcccg aaggttttaa
     5221 atatatagaa agaaataata ttgaagattt aaaaaataat cttgattcca cagtttgtgc
     5281 aataattctt gaagcgattc aaggcgaagg tggagttaat gttcttgaaa aagattatgt
     5341 tttggaaata gtaaaaatat gtcaagaaaa ggatattgta gtgatttttg atgaagtcca
     5401 atgcggtata ggaagaactg gtaaactttt tggctatgaa tattttgatg taaaaccaga
     5461 tatagttacc gtagcaaaag ggttgggagc aggaatacca gtaggaggag tattggtaaa
     5521 taaaaaactt tcaaaagtac taggaaaagg agaccaaggt acaacttttg gaggtaattt
     5581 attagctatg gtggcagctt cagttgtatt agatgagata tctaaagatg gcttttataa
     5641 tgaagtatta gaaaaaggaa attatataag aaaatctatt gaaagtttta ataacaaagt
     5701 tatattaaag acaaaaggta ttggtctaat gataggaatt gaaactaata ttgaatctag
     5761 tattatagaa gagaaagcta gaaaaaaagg attgcttatt ttgactgctg gaaaaaatgt
     5821 attgagattt ttaccaccat taacaatcag ttataaggaa atagatgagg ctcttgaaat
     5881 cctaaaagat atattactag aaattaacta aatattcaaa aaatagttga ttaaagataa
     5941 aaattagaag taaataaaaa agtaaagtgc taacaagttt aattgaattt aaaaagttta
     6001 taagaagggg cgaattaata tgaataatat aagtttaaaa ggtaagagtt ttttgacatt
     6061 aaaggatttt acaaaagaag agattagata tttattaact ttatcaagtt atttaaaaac
     6121 taagaaaaaa gttggtataa aaggcgattt gctacaagga aaaaatatag ctttattatt
     6181 tgagaaaaca tcaacaagaa ctagatgttc atttgaagta gcagctcatg atgaaggagc
     6241 acatgtaact tatctaggtc caaatgattg tcatatgggt aaaaaagagt ctgtatcaga
     6301 tacagcaaaa gttctaggaa gattctatga tggaatagaa tttagaggct ttaaacaaga
     6361 aacagttgaa agtctagcaa aatattctgg tgtacctgtt tggaatggac ttacagatga
     6421 atatcatcca acacaaatac tggcagattt tttaacagta attgaaaatg tagataaaga
     6481 tttgaataaa gttaaatttg tatatgttgg tgatgctaga aataatatgg ggaactcact
     6541 gatgatagga tgtgctaaaa tgggaataca tttcgtagca ctagcaccta aggaactttg
     6601 gccaaatgaa gaattggtta aggaaatgaa ggaaatagcc aagaaatcca aaggagatat
     6661 aatgttgact gaaaatattg atgatgttaa aggtgcagat gttatatata cagatgtatg
     6721 ggtttctatg ggagaagagg agcaatatga agcaagaata aatcaactta aagattatca
     6781 agtaaatatg gatatgataa agaaaactga aaatgaaaat gttatatttt tacactgtct
     6841 tccagcattt catgatttag aaactaaggt tgctcaggag atttatgaaa agttcggatt
     6901 atcagaatta gaggttacaa acgaggtatt taattcaaaa tattcaaagg tatttgaaga
     6961 agctgaaaat agaatgcata caataaaagc tgttatggtt tctactatga ctgatgtaaa
     7021 tatgaacaat aatttaatat agatatgttt taatatagac tttactttaa tgaaaattta
     7081 taaaatattt taaatatatt attcaaaaac tctcattata tgttaaaata acttatgtat
     7141 caacaaatta agagggagga tttgagatat gaaaaaaatc atattagctt taacaacttt
     7201 tttattagca atatctttaa cagcatgttc aagtgcaaaa ccagaagata caattgatag
     7261 tttttttaac agtgcgaaaa agtttgactt tgaaggcatg aataaggtaa tggaaaataa
     7321 tgacgaaaaa tataaggata tattaaagga attagataca aaagacccaa atgcccaata
     7381 tgttttagat tatctaaaac agaatgcatc taaaatcaca tatacaataa aagacagcga
     7441 ggttaaaggt gataaggcta caatcaaagt agaatgtaaa tttatagatt caacaccatt
     7501 acttcaagaa atagtagctg aggcatttac aaagatgatt ggtatgagtt tttcaggaca
     7561 agacttaact gatgagaaaa caactgaaat gttagtatca attatgaaag aaaaacaaaa
     7621 aagcgttaaa gagacttatg ttacaaaaaa tgtagagttt gaatgttcta aaaaggataa
     7681 taaatggata ataagttcag taaatgatgc agtagctgat gtattgttat ctaatcttgt
     7741 tacagcagga caagaatttt ctaactctat gaatacactt gaataatatt gtttaggtgt
     7801 agtaaagtaa taaatatatg attattttta taaataaaca tataaatatt tatgaaggat
     7861 accatttttg gtatcctttt tattaatata atgaaataca tggttaattt ctatattgtc
     7921 aagaaactat gatatatgtt ataagtctat actatttaaa ataaacttat aacatatatt
     7981 ttttataata tagtgtatga aaaatttatt taactaattt tagatattta ttgacaactg
     8041 attcagccaa gcattttgat gaatcaacaa tatttattga aggatatgat ttttctaaaa
     8101 ctacatttaa atcagtacaa gcaattacta tattttctat agattcattt ttaacatctt
     8161 caataagttt attccaaata tcaatattgt gtggattttc tttatccatt tttatatttt
     8221 gaataagatt gtttaatttt atttgccatt catctttaaa tataaattca tgtccattat
     8281 gtattatacc attctggtaa attgtagact caaaagttga actagtcgaa aaaagagtta
     8341 ctttttgtga gatagtaggt aattttttaa ctgtttcttc tacaatattt aatattggta
     8401 tattaataga ctcttttaat tctttaaagt atatatgtgc tgaattgcat ggcattgcaa
     8461 taaaatttac accagttgat tcaagctttt gtaatccatc aattatagtt tctttcataa
     8521 ggtcatgatt tattggacgg tcaatataaa atggggtagg taatgaatat atcatcatct
     8581 ttggaaattc atcatcatat tttgctccat attgagattg acactcatca ataattaaat
     8641 caacaaaagg ggctgttgac cttggaccca ttccagccaa aataccaatt aatttttcat
     8701 tcataaaaat tatctccttt ata
//
LOCUS       DAEPXW010000128         8715 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.132, whole genome shotgun sequence.
ACCESSION   DAEPXW010000128 DAEPXW010000000
VERSION     DAEPXW010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8715
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.132"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(77..592)
                     /locus_tag="KRM55_003263"
     CDS             complement(77..592)
                     /locus_tag="KRM55_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBH1595470.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(955..2025)
                     /gene="leuB"
                     /locus_tag="KRM55_003264"
     CDS             complement(955..2025)
                     /gene="leuB"
                     /locus_tag="KRM55_003264"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBH1595471.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(2032..2523)
                     /gene="leuD"
                     /locus_tag="KRM55_003265"
     CDS             complement(2032..2523)
                     /gene="leuD"
                     /locus_tag="KRM55_003265"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBH1595472.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(2538..3815)
                     /gene="leuC"
                     /locus_tag="KRM55_003266"
     CDS             complement(2538..3815)
                     /gene="leuC"
                     /locus_tag="KRM55_003266"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBH1595473.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(3772..5514)
                     /gene="leuA"
                     /locus_tag="KRM55_003267"
     CDS             complement(3772..5514)
                     /gene="leuA"
                     /locus_tag="KRM55_003267"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBH1595474.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(5637..5883)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6031..6477)
                     /locus_tag="KRM55_003268"
     CDS             complement(6031..6477)
                     /locus_tag="KRM55_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595475.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(6498..7217)
                     /locus_tag="KRM55_003269"
     CDS             complement(6498..7217)
                     /locus_tag="KRM55_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH1595476.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLKHLDYIIASL
                     HRPCIASGTKEKNTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(7335..8609)
                     /locus_tag="KRM55_003270"
     CDS             complement(7335..8609)
                     /locus_tag="KRM55_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBH1595477.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAKLQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
BASE COUNT         2640 a         1719 c          883 g         3473 t
ORIGIN      
        1 tatttttatt gtatttttga attttatttt ttctaaatat aaaatttatg ttttaaaatg
       61 taaaattttt atttaatcaa agttcaatat attccacttt ttctttcgat tcttcaaaaa
      121 accattcttc attagaaaaa tcaccttctg caatttgtcc aataggcatt ttcatatact
      181 ttccagttgc tgtcactgct atatctccat ttggtagaat tatttctcct gtaccttcaa
      241 ataattttct gttttcttta gttattcttc caacaacttt tatagtagca tctgttggta
      301 ctggtttctt atatttcaac tctaaagata ctgttactcc ccatatttgg tcatcattta
      361 tacttacagc tcttccaata gtctcatcca atattgcagc agacatacct ccatgaactc
      421 tcccaggata actttgatgc caatcctttg tattacaaat tgatacaagc tctccatttt
      481 caagttcata aaaatctgct ttaagtccta gctcattttg tgttccacaa actaaacaag
      541 atttactact attttgcttc ttcaaaactt tatactttgc caaaaaatcc atctcctaac
      601 cgacattagt agtcgcttaa tattaaataa ttctaaaata tattatataa tattaataaa
      661 atccctgcaa acttctaata ataaaaatag gctacttcaa tatgataagt ttaatttaaa
      721 gtattatttt ccaaaaaata actttatcaa aatagaaact caaagtagat ataagcctct
      781 ttttcgttat taaaatagta aaaatatatt ttacttaata taaaaaagag tgtctcatta
      841 actaataaag tttattttga gacacccctc ataaaacaaa ttatactaca atagattttt
      901 actaattcta caagttatat attcaaatta tattattcaa attaaactat aattctaaat
      961 ttcatttact attaattcgc ccatttccct tgttcctaca acatttccca caccattata
     1021 gatatcaata gttctataac ctttattgag tacactttgt acagcatctt caatacactt
     1081 agcttcttct tctaagttaa aactatgtct taacatcatg cttacagata gaatagtcgc
     1141 aattggattt acaatatctt ttccagctat atcaggtgca cttccatgta ttggttcata
     1201 cataccaaaa ctatcttctc taagtgatgc tgatggtaac atacctatag aacccgtaat
     1261 catagatgct tcatcagata ttatatctcc aaatatatta ttagtcacta ttacatcaaa
     1321 ttggctaggg tcttttacaa cttgcatagc agcattatca acatacatat gtgacagttc
     1381 tacatcttca aactctttag ctaagtcttc cattatactt ctccaaagtc ttgaactctc
     1441 aagcacattt gccttatcta cacttataag ttttttattt ctatttctgg ctatttcaaa
     1501 agctctctta ccaattcttc ttatttcatt ttcgttatat atttctacat cataagcatt
     1561 ttcgatacca tcaatgattt ttcttccacg ttctccaaaa taaatgcccc ctgttaattc
     1621 ccttacaaca acaaaatcaa tgcctttctc aactatatcc gttctaagtg gtgaagcttc
     1681 ttttatactt tcatacattg tagctggtct taaatttgca aataaaccca atgactctct
     1741 taattttaaa agaccagact ctggtctttt atctccctta catttatccc actttggtcc
     1801 tccaacagca ccaagcaata cagcttcgtt ttttcgacaa gtttcaacag ttttattagg
     1861 tagaggttct ccagtttcat caatcgcgca tcctccagct aatacatatt cacaatcgaa
     1921 tctatgatta aatttacaac aaattttatt tagaaccttt ataccttcat ctataatttc
     1981 cggtccaaca ccatcacctt ttatgactgc tatattacaa ttcatacttc actaccccct
     2041 atttgctttt attgagttaa ttaagccttc atttaatata atattttgca taaactcagg
     2101 aaatggttct gctttatatt cttttccttt tgttatattt tttatcacac ctgtagaaaa
     2161 atctacttct atattatccc cttcatctat gttattggca gcttcttcac attcaagtat
     2221 aggaagccct atatttatag agtttctaaa aaatattcta gcaaaagtag aagcaatcac
     2281 acaggatact ccactttctt ttattacaat tggtgcatgt tctcttgatg aaccacaacc
     2341 aaagttttta gttgcaacta taatatctcc tttttttacc ttagaaataa atttatcatc
     2401 aatatcctcc atacaatgcg ttgctagttc tttataatca gctatattta aatatctagc
     2461 tggtattatt acatctgtat ctatattgtc accgaattta aaaacacttc cattggcaat
     2521 cataaatttt acctccctta aattatttct gatggttttg atatttttcc agttatagct
     2581 gatgctgctg ctacagctgg gcttgcaaga tacacctctg aatcaacatg ccccattctt
     2641 cctacgaaat tcctatttgt tgttgaaatg gatttttctc ctgctgcaag tatacccata
     2701 tgtcccccta gacatggacc acaagttggt gtagaaactg ctgctcctgc ctctataaaa
     2761 gtggtaatat accctttttc tatagcttca agatatactt tttgagttcc aggaaatatc
     2821 ataactctaa ctccatctgc tacttttttg cctttcatta tctcagctac tacttcaagg
     2881 tctgatattc ttccatttgt acaagagcct attacaactt ggtctatctt tatatcctta
     2941 tctatctcat ctactgttct agtattttca ggaagatgag gaaaggctac tgtttctttt
     3001 agttcagcta aatctatttc gtatacttca tcatagactg catcttcatc tgcttcatat
     3061 atatttacat cttttgtcat agttgaacac ttatgtgaat ttatatattc catagtctta
     3121 tcgtctactg gaaaaattcc attttttgct cctgcttcta ttgccatatt acaaatagta
     3181 aatctatcat ccatagataa gtattctact ccatctccac aaaattccat tgacttgtaa
     3241 agtgctccat caacacctat ctcccctatt atatgaagta ttatatcttt accacttatc
     3301 catttatttg gtttattctt caaaacaaat tttattgctc caggaacctt aaaccaacat
     3361 tttcctgtag ccatacctgc tcccatatca gttgaaccta caccagtaga aaatgctcct
     3421 aatgctccat atgtgcaagt atgagagtca gcacctataa ttacatctcc agcagttact
     3481 ataccttttt caggaagaag aacatgctct attcccatat ctcctacatc aaaaaaattt
     3541 acaactcctt ttgattttgc gaaacttctt gtaaatttac attgttctgc actctttata
     3601 tctttattag gtgtaaagtg gtctaaaacc atcactactt tagtcttatc ataaacatct
     3661 tcaattccta atttttcaaa ttctctaatg gctactggtg atgttatatc attacctaaa
     3721 actacatcta aatctgcttc gattaattgc cctttcttaa cttcatttaa tttagcatgt
     3781 ttggctaata ttttctgcgt catagtcatc cccatttttt atttcctcct caatataact
     3841 tttatttatt gcattcataa gtgcattaat agctgctgta tttatgtttt ccgatatact
     3901 tacaccaaaa tagacttcat tattgtgctc tattcctaca taagctaccc ctcttgaatg
     3961 tgacccttcc tctaatgcat gttcccagta atatctaaat ttataatctt tcatgccaca
     4021 ttgctttagt gcattattaa atgaatctac aggtccattt cctataccaa caatcctttg
     4081 ttcatttccc atataactta ttcttgcagt catctcaatc atgttagtat cattagaatc
     4141 atcattttca tagtttaatt catccattga ttttatttta tacttcttaa ctttataagg
     4201 gctctcaact tcaatatatt ctttcttaaa caaattaaat attgcttcac tactaagttc
     4261 ttccccaatt ctatcagatt ccattttgac tacatttcca aaatcagaat gcatattctt
     4321 aggtatcata aatccataat ctgtttccat tatataaaca gctcctcctt ttccagattg
     4381 gctatttatc cttataattt ctttgtattc tcttccaata tcatgagggt ctattggtaa
     4441 atatggaact tcccagtaat cattatctct gtttttcatt gctatcatgc cttttctaat
     4501 agcatcttga tgtgaacctg aaaaagcaca atgtacaaga ttacctgcat atggatgtct
     4561 atcatgtacc ataagttttg tacagtcttc atatatacct attatcttat ctatattgct
     4621 aaaatctagc tctgggtcta ttccttgtgt ataaagatta agtcccacat ttactatatc
     4681 catattccca gttctttcac catttccaaa tagtgttcct tcaagtctat cggcaccagc
     4741 caataatcca agttcacttg cagccgtaca agttcctcta tcattgtgag tatgcaaact
     4801 tagtataata gaatccctac aacttatatt tttacaaaac cattctattt ggtctgcata
     4861 tacgtttggt gttgccattt caactgttga tggaagattt attattactt ttttttgagg
     4921 agttggtttc caaacatcta tcactgcctc acatatttca agtgcataat ccatctctgt
     4981 tcctgtaaaa ctctctggtg aatattcaaa agtaaattct gtttctggat atttttttac
     5041 ttcttcatta aataattttg ctccttcaac tgctatatct attatttctt gtttactcat
     5101 attaaaaacc acatctcttt gaagaacaga tgtagagtta tataaatgta taattgcttt
     5161 tttacatccc cttattgatt caaatgtttt ttctataaga tgagccctag attgtgtaag
     5221 tacttgtata gttacatcat ctggaatcat attctcatct attaattttc ttaaaaatgt
     5281 atactctgta tttgatgctg atggaaatcc tacctctatt tctttaaatc ctgtatcaat
     5341 aagcattttg aacattctga ctttttcatt tacactcata ggtgttggca gtgactgatt
     5401 tccgtctctt aaatcgacac tacaccaaat tggagcctta aatatttcat tatctggcca
     5461 tttacgattt actatttgca ttttatcata ttttttatac tttccacact tcatgttatt
     5521 tccccctttt ttgttttttg tattcagtat acctcatatc gacgcaatcc tgcacaattc
     5581 ataaggataa atgtcaattt tatcattaga ataaaaaaaa cctcatctct aataaaatta
     5641 gagacgaggt tttgctcgcg gtaccactct atttagcttt ctaaaaagct cccttagtaa
     5701 tagccaatac aataattata atgactatat ttcctataac gtggaattac tccgattatt
     5761 ctaagattta aatcttagaa aacagctcct agacaagttc agaactatca actactaaat
     5821 cacaccatcc tttagctctc tgaaagtttc attgttctta ctacttctat tcatcacttt
     5881 tttaatcatt taaattttct aaatattttg atttaatagt tattatatac acattaaaat
     5941 gtattgtcaa cacaaaaaat aattatctca attttttatt tttgataagc aattctataa
     6001 aacatgctaa ctattgaaaa cagtatgata ttatgcctta aactttttca tcttttcatc
     6061 tatgatattc aataattttt tttcatcttc caaactcaat gcccttaatc taattttata
     6121 attagattcg tcagtgtata tatttaatat attttttact acttctattt tttctattat
     6181 cttataatta aacttttgac tttgtttaga ttttatactg aatatacatt gattatttat
     6241 taatattgaa tgattatcga gagtaatata tacttttccc tcatatttat ttgaaaaatc
     6301 acgaccttgt ttaaatagaa aaactgctgt tattatacat aaaatatata atattgtcgt
     6361 tgaatatata aaaattgtag ctaaaattat aagtgctaaa accatatata tagtcattcc
     6421 ttttttaaaa taaccattgt cataataatt catatagata aacttatttt tactcaaatt
     6481 ttttcactcc caagattcta aaaatttata tcaaaaaatt ctataatttc atcttcatga
     6541 taatttatga ctaattcatc tggaaaatct actgcttcta aaactttttc tgcattttca
     6601 aattctccta tagaataaca tatatgagag tcagtaccaa gaattactct tgcaccatat
     6661 gttttacaca atgtcaacat atgacttaca ttttcccaag tacccgttct atgagagttt
     6721 gaacttaatg atgaattatt tatttctaaa aggatatttt tatctttagc tttttttact
     6781 ataggttcat aatctaaagg atacctactg tcatctggat gtccaattat ttttacctta
     6841 ggtttatcca taacttttaa aatagcattt gtattttttt cttttgtacc agaggctata
     6901 caaggtctat gcaaacttgc gattatataa tccaaatgtt tcaacatatc ttcttgaaca
     6961 tctaaattac cattataatc cattatattt ccttctattc ctctaagaat ctttacgcct
     7021 tgcacttcac gtggaagcaa atgcaaatta taaaaataga atggatgtgg tcctcctggc
     7081 atattaggtc catggtctga tattcctaag tattttatat tcttcttact cgcctcttcg
     7141 acattttcct tgaaagtact atgtgcatgt ccacttatta gagtgtgaca atgtacatcc
     7201 ataatagact ttttcattaa atttcctcct aatattttac ataaattcgt gaaaatagct
     7261 aaagggctat ttcaaaacta aagctgtcat aatagacagt gtaacgtttt aaaacagccc
     7321 cattttcaat tattttacac ttctaaatct ttaaatttat ctttaaataa ttctccaata
     7381 cttcctaaag attcctctac ttctaggtat tctgttatat cctcttctgg ctctctagtt
     7441 gcttctttta ttgaaaccaa cattctttta gtctttggtt taaaatcaag aatcttaact
     7501 ttaacctcat ctccaatatt aacaacatta gtaactttag ccactctagt atcactcaat
     7561 tcagatattg gtaaatacgc atctacacct tctttaattt gaacaaaagc ccctttttct
     7621 attattctaa gaactttagc attgacaaca tcatcaattt gtacttcttt tgctattaaa
     7681 tcccaagggt cattatttat gtcttttaat gccaaggcaa tttttttagt ctctttattt
     7741 acatccaaca cataaacttc tacttcttgt ccctctgaaa caacatcttc aacactttca
     7801 actcttgtcc aagctaaatt atttatatgt gctaatcctt caatcccacc aatatccaca
     7861 aatgcaccat aaggcattat ctttgtcacc ttaccatctc ttttttgtcc aacttcaaga
     7921 gaattaaata agtcttcttt agctgctttg atacgagctt tttcttcttc tctttcttgc
     7981 ttaattcttg ctctttcagc ttctttttct gccttaattt gagctcttct ttcttctctc
     8041 tctttattta tacgctcttg taatacatct ctatgagatg ctacaagtct attttttcta
     8101 acatccaatt cttttatata aacttctaag ttaagaccaa caaatttaga tgtatctgta
     8161 ataaattttg tatcaagttg agaaattggt ataaaaaatg tatatgtatt gtaattagca
     8221 aatacacctt tatctatatt cttttcaaca tttacagtta ttattctatg ttcatcataa
     8281 gccttttgta acttggcaaa atcatttctt ttgtcaagtt gtaatttaga taaagttatt
     8341 gtaccatctt tttgagatac ttttgttatt acagcagtta tttcatcacc tatgtggtat
     8401 atatcttcta tatattgatt tttttctatg ttcaattcac ttataggtat tattccatca
     8461 aacccatagt ctaatcctaa ttgtacttca tcatttctca ctgcagttat ttttccagtt
     8521 gtcaattctc caactttcac tttgctgaat acttgttctt gctggtcaag taattcttgc
     8581 attgttaaat cattttccat tataaacatc ctttcctctt attgattatc atatctgtaa
     8641 atattatacc attaatattg caaatactta catttttctt actataattt ttaaaataaa
     8701 ttcaacttca tatat
//
LOCUS       DAEPXW010000129         8682 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.133, whole genome shotgun sequence.
ACCESSION   DAEPXW010000129 DAEPXW010000000
VERSION     DAEPXW010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8682
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.133"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            93..1583
                     /locus_tag="KRM55_003271"
     CDS             93..1583
                     /locus_tag="KRM55_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1595478.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            1863..3359
                     /locus_tag="KRM55_003272"
     CDS             1863..3359
                     /locus_tag="KRM55_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1595479.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            3504..4430
                     /locus_tag="KRM55_003273"
     CDS             3504..4430
                     /locus_tag="KRM55_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1595480.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINGAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDSKTLSVNQ"
     gene            4548..4739
                     /locus_tag="KRM55_003274"
     CDS             4548..4739
                     /locus_tag="KRM55_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595481.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            4962..5312
                     /locus_tag="KRM55_003275"
     CDS             4962..5312
                     /locus_tag="KRM55_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595482.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            5574..7079
                     /locus_tag="KRM55_003276"
     CDS             5574..7079
                     /locus_tag="KRM55_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBH1595483.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            7469..8566
                     /gene="dinB"
                     /locus_tag="KRM55_003277"
     CDS             7469..8566
                     /gene="dinB"
                     /locus_tag="KRM55_003277"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBH1595484.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
BASE COUNT         3438 a          880 c         1609 g         2755 t
ORIGIN      
        1 ttaaacatat aatattttat gtatatatta ataaaaggac atattgtgtt ataatggtat
       61 cgtataaaat catttacggg ggtggtatta aaatgtttca atttgaaaca caaatacaca
      121 aattaagaca tgatgtttta actgcaatag ctagacttgg aaaagaagat aaccttacca
      181 gagaagcaat ggataatatt cagtatgaaa taataaaagg tgagaaacct acatacagat
      241 gctgtgttta taaagaaaga gctataatat ctgagagagt aaatgtaagt atggggttac
      301 aaccaggtca agataagata gatttagata caatggatat agaagaagat gaacaaatta
      361 tatatatttt ggaagctgca tgtgacagtt gtccaataaa tgaatttaca gtaacagata
      421 tttgtagagg atgtctagca catagatgta aagaagcttg taaatttgga gctataacac
      481 atgtcggagg aatggcctat ataaatcatg aattatgtaa ggcttgtgga atgtgtaaaa
      541 aagcttgtca atatgatgcc atctcagagg ttgttagacc atgtaagagt gtttgtccaa
      601 ctaatgcctt aggatttgat agagaaaata tgaaagctat gatacatgag gataaatgtt
      661 taaactgtgg agcatgtatg tcagcatgtc catttggagc aatatctgat aagagtttga
      721 tagctcctgt agctagaaag ttagttcaaa aagagaaaat gtatgcggtg gtagctccag
      781 ctataacagg tcaagttgaa gcaaatgtta catatggtca aataaaaaat gctataaaat
      841 cactaggatt tgttgatgta ttagaagcag cttgtggagc agatgcagtt acagttcatg
      901 aaagcttaga atttgctgaa agaatggaaa agggagaagc ttttatgaca aattcttgtt
      961 gtccaggatt tgttggttat atagaaaaaa catacccaaa tcatgtagga aaaatatctt
     1021 ctactgtgtc tcctatgata gctagtggta gatttataaa aagtcatgaa ccagatgcta
     1081 aagttgtatt cataggacca tgtacagcca aaaagagtga ggcagctaag aaagaattaa
     1141 aaggagctgt tgattatgta cttacttttg aagaaataat ggcattattt gaggcatttg
     1201 atatagactt ggctaagtgt tcaaatgaag atatagatga tgcatcaatt tttggaagag
     1261 gttttggagc tgctggtggt cttacaaaag ctatagaaaa ttatcttgct gaaaaaggta
     1321 ttggtgttaa ttttgaacct gtaaagattt ctggttcaag agaaatcaag aaaactatga
     1381 ctatggctaa tttaggaaag ctagaaggta attttataga aggaatgatg tgtgaaggtg
     1441 gttgtataaa tggttctggt aaattcttat caggtgcaaa ggttaaagcc acttttgata
     1501 gaaaaaattc tcaatcaact aagaaaagtg tcttagcaaa tacaaagata aaagatttta
     1561 gtaatataaa tttagaaaaa taaagataat acaaagcaac aaaaatacat attgttaata
     1621 gagttgttct aagttgaggt ttaacttttg gacaactcta tttttattta tatatttaat
     1681 tattgaacga ctgaaataaa aattatatac acttaaaata aaaattacat atataatatt
     1741 ttgtatataa cttaacaaag tatatgccta tgttataata atttatagaa ataaataaaa
     1801 aatacaatat acataatagt agaaatatag caaaaaggtg tgatttatag ggaggattac
     1861 ttatgtttga atttgaaacg caactaaaaa ggttaaaaca tgaagtttta acagcagtag
     1921 caagactatc tattgaagaa aatttaacaa aagaaaatat agaaaaaatt ccatatgaaa
     1981 taattaaagg agaaaaggcg agatatagat gttgtgttta taaagagaga gaagtagttc
     2041 ttgaaagggc acaacttgca ttaagtttaa ctccaaatag taaatatgga gatataaatc
     2101 cagattcagt tagtttggac acagatgagc aaattatata tatagttgaa gcagcatgtg
     2161 atagatgtcc aataaatgaa tttacagtta cagagctttg tagagggtgt ttggctcata
     2221 gatgtaagga agcatgtaaa tttggggcaa tttcttatat aaatgggaga gcatatataa
     2281 atcatgattt atgtaaggct tgtggaatgt gcaaaagttc atgtcaatat gatgctatat
     2341 cagaagttgt aagaccttgt aaaagcgttt gtccaacagg agctttggat tttaatagaa
     2401 acactatgaa agcaatgata catgaagata attgtataaa ttgtggagca tgtatgtcag
     2461 catgtccttt tggagcaata tctgataaga gtttgatagc acctgttgca aaaaaacttg
     2521 caaagaaaga aaatatgtat gcaatagtag ctccagctat aacaggtcaa atagatagta
     2581 atattacata tggtcagtta aaaaatgcta taaaatcact gggatttgta gatatgatag
     2641 aagcttcttg tggagcagat gcagttacag ttcatgaaag caatgaactt attgaaagaa
     2701 taaaatcagg agataattac atgacaaatt catgttgtcc gggatttttt aagtatatag
     2761 agaagatgtt cccagatgaa aaagatagaa tatcatctac agtgtctcct atggtagcaa
     2821 caggaagatt agtaaaaaaa atagattctg atgctaaagt tgtatttata ggtccatgta
     2881 cagctaaaaa gagtgaggca acagagaaaa gtttaaaaga ttcagtagat tatgtactta
     2941 cttttgaaga actaatggca ttatttgaag catttaatat agatttatca aaatgttcaa
     3001 atgaagatat aaatgatggt tcgatttttg gaaggggatt tggagcatct ggtggacttg
     3061 ccaaatcagt acagaactat attgctgaaa aggggcttag ttttgatttt gaacctataa
     3121 aagtatctgg tccaagacaa attaaaaaga caatgacaat ggctaaattg ggaagattag
     3181 aaggtaattt tatagaagga atgatgtgtg aagaaggttg tattaatgga gcaggtaagt
     3241 ttttatcagg tgtaaaagct aaaaatactt ttgatagaaa aaatggacaa tctactaaaa
     3301 agagtgtttt atctaatgat aagattaaag aatttgaaga tgtaaattta gaaagataat
     3361 tgttttggta cagtcatttt tttatcatgt ttttatcatg ccacaaatat gcctaaaatt
     3421 tgcccttttt atatgtgtat tttacagagt taaggttgct atactataaa tatgtaataa
     3481 ataaaattta taggagcttt tggatgagga aaatagtatt aaaagatatc ctgtttttag
     3541 ttactacatt atctataata gtaatattat tgcttgtaac aaatataact actaatagta
     3601 agataaaatc aacaagtgaa tcttatttaa aaagtgacaa aaatagtgtg aggcaaaatg
     3661 gtatccagag gagcacaaag agtagcacaa aaaatactgc atttaagact actatactaa
     3721 acactggaaa gtctgattgc atattggttg agataggtaa caaagtcata atgattgata
     3781 caggagaaga taaaaatgga aaacaaatag tggataggtt aaaagaaaaa ggaataaata
     3841 cacttgacta tttaatttta actcatttag ataaggacca tataggtgga gtagatagtg
     3901 tgttatctag tgttaaagta aagaatatta tacaagcaaa ttataagaaa gatagtaagc
     3961 aatatgatga atatattgac tcacttaaaa aagctgatat agaaccagtg ctactaaaag
     4021 ataatatgaa tattgtaatc aatggtgcag aaataaacat acatccggct tcaaaaagca
     4081 agtacgagag ttcaaatgat tattcaataa tcactaatat aagctatgga gcacataagt
     4141 ttttatttgc aggagatgca gaggaagaaa gattgtcaga gtttataaat ggaaatactt
     4201 taaaatatga ttttgttaaa atgcctcatc atggaagata tgacaaatta actgaaacat
     4261 ttttagagtc tatttcaccc caatatgctg ttattacatg ttcagagaaa aaagaaccag
     4321 aggaaggtgt tttaaaaata ttggaaagat tgaatataaa aacatttttg acttctaatg
     4381 gagaggtagt tatcaatagt gatagtaaga cattgagtgt gaatcaataa tttttttaaa
     4441 aatatctaaa aaaatttaaa aaaatcatta gcaaatatta ccccttaaac atagtatatt
     4501 ttaggagctg aaactccaca tacaaaatga ctaggaggta acatattatg ttggatagat
     4561 tttttggtga aggcggattt ggtggatgtg cttggtggat aataatatta ttcttcttat
     4621 tcttagcatt ccaagattgt tgggctgaaa tggacttatg tgcatggata cctttcttaa
     4681 tattattatt aatactttgt gaatgtggtg acgtttttga tggaggatgt ggatgctaaa
     4741 aaaatcaatt tagatgattt aataaagctt atggtgggta taaataaaat accaaaccaa
     4801 tcacaatcta gtgtttgaag gtagtcggaa atcccccgct accttctttt ttttattgtt
     4861 aaaatttatt tttgaattat ttcatttaca tataataatt tttacgataa agtctgatat
     4921 aattaaaaag aaaataaaat ttatttatag gagatgtaaa aatggctata gtggataaga
     4981 ttttcaatga gataaaactt atggttgcaa gacttttatt gggaaaaaaa tacagtgaat
     5041 atgaagaaaa agatttagtg tataatacag aagaagaagt tatacttata actttaaaaa
     5101 gattagtttt tcagggaaat gtaaacgaag cagaagaaat tttatttgat aaagctaaga
     5161 gtgtaaatag tgaaaatatg cagtatatag caatagaatt ttatactatg cttatggaaa
     5221 aaactgatga agaattagaa gctatgaatt tttctaaaca agaagtttat caaggtatag
     5281 aagatattag aaaagtattg aatttagaat aaaagatata tgaaaatatt gaaataaatt
     5341 aatgctaagg tgagaatatt atacttatat ataaaaatat agtattctta ttttattagt
     5401 tatattaggt atatcttatt taccataaaa ctatcttgaa aaaaattaat cttaattgta
     5461 taatattact ttgagtgaaa aagtattaac atttttttat aagatgtttt actaaaaaaa
     5521 tatatataaa tatactgtta tcaataagaa atttaattta gtgaggtgtt aagatgaaag
     5581 taggatttga ccacaaaaaa tatttagaag agcagtctaa atatatctta gaaagagtaa
     5641 ataattttga caaactttat ttagagtttg gaggaaaatt gatgggagac cttcatgcaa
     5701 aaagagtact tccaggattt gatgaaaatg caaagataaa agtattacaa catatgaaag
     5761 aaaaagttga agttgtaatt tgtgtctatg caggagatat agaaagaaac aaaataagag
     5821 gagactttgg tatcacttat gatatggaag ttttaagatt aatagatgat ttaagaggtt
     5881 atgaactaga tgtaaatagt gtagtaatta ctagatttga aggacaacct gctacaactg
     5941 tatttataaa taaattagaa cgtagaggaa ttaaagttta taagcattat ccaacaaagg
     6001 gatatccgtc agatgttgag actatagtta gtgatgaggg atatggagca aatgaatata
     6061 tagaaactac aaagccaata gtagtagtca cagcaccagg acctaatagt ggaaaacttg
     6121 gtacttgtct aagtcagttg tatcatgaaa ataaaagagg taatgtagtt ggatattcta
     6181 agtttgagac attcccagtt tggaatgtac ctgtaaaaca tcctttgaat atagcttatg
     6241 aagcagctac agttgattta aaagatgtga atatgataga ttcattccac cttgaaacgt
     6301 atggtgaaat gtcagtaaac tacaatagag atttggaatt atttccagtg cttaaaaaaa
     6361 taatagaaaa gataactgga aaagaatcaa ttttccaatc tccaactgat atgggtgtta
     6421 atagagttgg ctttggaata atagatgatg aagtaataag aaaagcttct atagaagaaa
     6481 taataagaag atactttaaa actgcctgtg agtataaaaa gggacaagtt gataaaggtg
     6541 cttatgatag aatgaaaatg attatggaag agcttaactt aaagccagaa gatagaaatg
     6601 ttgtattacc tgctagaaac tacagtaata aattgaaaga aagtgccgac aagaatgata
     6661 cttgtcctgt agttgcatta gaattagaag atggtacaat attaactggt aagggttctg
     6721 atttaatgaa tggaactgca gcagtagtat taaatgccat taaacattta gccaatatat
     6781 ctgatgatat gcacttaata tcacctgtaa tattagaacc tatcataaac ttaaaaacaa
     6841 agactttagc tagtagaaat gtttcactta gttgccaaga ggtgttaact gcacttagta
     6901 tttgtgctgt aactaatcca actgcacaat ttgctatgga aaagttagca ttattaaaag
     6961 ggtgtcaagc tcattctact actatattaa atagagatga tgaacaaaca tttagaaaac
     7021 ttggtataga tgtaacttgt gacccagaat atccttcaca aaatctttac tatagttaaa
     7081 attatataaa aaaatatggg ctgttttaaa gtaatagttt gagcagtcca ttacaattat
     7141 aataaaatca gtaggctgtc ttgtataaga cagtcttttg tttttaaaac atcccataaa
     7201 ttaaatatat atactgttat ccataaggaa ttttaaattt agttccttgg aatacctatt
     7261 gtaaagcttt tatatagttt ttgcaagtgt ttttaaggat tttttataaa ttatattgaa
     7321 gttaatggat tatagatggt tttatttatg gaaaatatga atatataaag aaaataatga
     7381 aaaaatacca aaaagaaaca taagtttggt ataattaaaa agtaatataa ataaaattaa
     7441 tctatttata ctttaaaagg tgataataat gaaacattat agaaaaataa ttcatataga
     7501 tatggacgct ttttatgcat ctatagaaca aagagataat aaaaaattaa aaggaagacc
     7561 tgttattgtc ggtggaaatc cacaaagccg aggtgtggtt gcaacgtgtt cttatgaagc
     7621 tagaaaattt ggtatccatt cagctatgcc atcagctgta gcttacaata ggtgtccata
     7681 tgcagttttt gtaagaccta gatttgatgt ttataagagt gtgtcagagc aaataagaga
     7741 tatattttat agatacacag atttagttga accattatct ttagatgaag cttacttaga
     7801 tgtaacaaaa aataaaaaaa atattgattc atcaattgag atagcaaagc aaataaaaaa
     7861 agatatattt agagaagttg gtcttacttc ttcagctggt gtgtcataca ataagtttct
     7921 tgctaagatt gcatcagact taagaaagcc aaatggatta actgtaataa ccgaagaaaa
     7981 tgcccaggac tttttagata aattacctgt gaataaattt tttggtgttg gaaaagttac
     8041 ttcaaatact cttaaaaatt taggtataaa aactggatat gatttaaggt gtttaaattt
     8101 atttgaactt gaaaatatat tcaaaaaaag aggttatgaa ttatataaat ttgctagagg
     8161 aatagacgat agaccagtgg aaccaaatag ggttagaaaa tctgttgggg ctgagactac
     8221 attaagtcat aatttggata ttgatgaaga agaaacacgc aacattcttg atgaactttg
     8281 tgaagaagta tgtcatagat taaaaaactc tgagaagttt ggaaaaacat taacattaaa
     8341 aattaaatat gaggacttta caaagataac tagaagcctt agtttagaac actatattga
     8401 cgaatataat gatataagaa gtggtgtaga taatttgttg agaaatgttg aggttaatgg
     8461 aaaacaaatt aggctattgg gagttacaat atcaaaccta agtgataaaa aagaaactta
     8521 taaagatatt acattatttg aatacatgga tagtatccaa atgtgagttt tgtttaaatg
     8581 aaataacact agctttaata ctatataatt gaggctagtg ttattttatg aatattttta
     8641 tattttatat tttttgtttt ttgacattat atattatata ct
//
LOCUS       DAEPXW010000130         8664 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.134, whole genome shotgun sequence.
ACCESSION   DAEPXW010000130 DAEPXW010000000
VERSION     DAEPXW010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.134"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            47..814
                     /locus_tag="KRM55_003278"
     CDS             47..814
                     /locus_tag="KRM55_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH1595485.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            1097..1294
                     /locus_tag="KRM55_003279"
     CDS             1097..1294
                     /locus_tag="KRM55_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1595486.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            1323..2399
                     /gene="vorB"
                     /locus_tag="KRM55_003280"
     CDS             1323..2399
                     /gene="vorB"
                     /locus_tag="KRM55_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH1595487.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            2402..3121
                     /locus_tag="KRM55_003281"
     CDS             2402..3121
                     /locus_tag="KRM55_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH1595488.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            3134..3673
                     /locus_tag="KRM55_003282"
     CDS             3134..3673
                     /locus_tag="KRM55_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH1595489.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            3830..4888
                     /gene="buk"
                     /locus_tag="KRM55_003283"
     CDS             3830..4888
                     /gene="buk"
                     /locus_tag="KRM55_003283"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH1595490.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            4906..5799
                     /locus_tag="KRM55_003284"
     CDS             4906..5799
                     /locus_tag="KRM55_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH1595491.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            5829..7037
                     /locus_tag="KRM55_003285"
     CDS             5829..7037
                     /locus_tag="KRM55_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1595492.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            7061..8320
                     /locus_tag="KRM55_003286"
     CDS             7061..8320
                     /locus_tag="KRM55_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1595493.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
BASE COUNT         3362 a          968 c         1731 g         2603 t
ORIGIN      
        1 agagtgtggg agtagcactt aatatttgca ggaggagttt ttgtatatgg gagaaataat
       61 aaatgcatta gatagagccc tagacataat tttgctgtta tatcatgaaa agagagaaat
      121 gggaataact gaaataagca aggctatggg agtatataaa agtactgtac atagaacttt
      181 ggttactctt gaaaacaaag gttttgttat acaaaatgca gagaatggta agtattggct
      241 aggaataaat ttatatgcaa taggtatggt tgtgggagaa aaaatgtcat tgactgaaat
      301 agtaaaacca tatacgaaaa aattaaatca agaatttaac gaagtagtta atgtatctat
      361 attagaagaa agagctcaag attctccaag aagtatcata atacataaag agtatggttc
      421 aaatcaatta ctttcagtaa atccatccgt tggttcaagt agtgaatgtt attgttcagc
      481 agttggtaaa tgtcttatgg catttaatga ttctatagat tttgaaaaat atagaaaaac
      541 accaatacac aagtatacag aacatacaat tgataattgg gatgatatga tgcttttttt
      601 agcaaaaata aaagaacaag gatatgctat agatgatgaa gaactagaac atggactaac
      661 ttgtattgga gcacctatct tagataaaaa taataaagct attgcagcca taagtttgtc
      721 aggtccaact ataagaatga gagaagggga ctttgagtat aagattaaaa gagttataga
      781 aactgcaaaa agtatatctg aactttttag atgattttta atctcgataa taaaaatagg
      841 ctatatttaa attgttattt gtaaatatca gtttaaatgt agcctatttt tctttaatct
      901 aaaattaaat attcttaaaa tttaaaatgt tattgaaata tataagcgaa tgtgttatct
      961 tttaattaag caataaaaat agaacaaggt tctatactat agaacaaaat tgatgcatat
     1021 atagtattta tacaaaatat aaatattata tatttaaaat taagtaaaaa tattacataa
     1081 aggggagatt tgagaaatgg aaaaagtcaa gttgagtgtt gaaagatgta agggatgcta
     1141 tctttgtatt gaagcttgta aaaaagatgc aataagtctt tctgactaca caaataaaaa
     1201 aggctttgta actattaaag tcgatgaaga aaaatgtatt caatgtggcg cttgttatac
     1261 aatgtgccct gatttagtat ttgagatatt ataaattatt tttattagag gggagaaaag
     1321 gtatgcaaag tttattaatt aaaggaaatg aagctttagc agaaggtgct atacgtggtg
     1381 gctgcagatt ttatgcaggt tatccaataa cgccacaatc agaaatatta gaaatgatgg
     1441 catggagaca aaaagaagtt ggaggagtat ttatccaagg tgaatcagaa atagccagtg
     1501 taaatatggt tatgggagca agtgcacttg gagcaagagc tatgacttct tcatctggtc
     1561 caggattttc attaaaacaa gaaggtattg catattgggt atcagctggt ttgccagcag
     1621 ttgtagcatg tgtgcaaaga tatggtatag gtgatggatt tataggagct ggtcaagata
     1681 attattggca agcagtaaaa ggcggtggaa atggagatta tcatttaatc gtgttagcac
     1741 ctaatagtgt tcaagaaaat atggatatgg catatgaatc ttttgaattg gctgaaaaat
     1801 atatgcatcc agtacttata ctttctgatg ctacaatagg tcaaatggta gaaccttgta
     1861 tagcaccacc aatgaaagaa tacgatatgg ataaagctcc atgggctgca aaaggaacac
     1921 ctgtaggaga aaaaaataaa gtaataactg atataacata ttttgaagac caagatacat
     1981 ggcaaaaagg gtatatagaa aaaatgagaa aagttcaaga agatgaacaa agatgggaag
     2041 agatagaaat agaagatgct gaagtggtat ttgtggcata cggtatttca tcaagaatag
     2101 cagaaggtgc agttagagat gctagagcaa aaggaatgaa attaggtcta ataagaccaa
     2161 aaacattgtg gccttaccca agaaaagcat ttaagaaatt aagtgattca ttgaagggac
     2221 ttgtaacagt tgaaatgaac atgatggcac agatgaagga agatgtaatt atagcatgtg
     2281 ataatagatt tccagtatat tcagtagcaa cagctcaata tatggcagaa gtaaatcaat
     2341 taatagattt tgctcaacag attatagatg gaaaagctaa gcaagaggag gtattttaat
     2401 tatggctaaa aaagcaccag caataatgat gtgtgaaaat atgttctgtg gaggctgtgg
     2461 acactctata gtcgatagaa ttattggaga agtattaaca gaaatggata tatgtcaaga
     2521 tacaattata tgttcagata taggttgtaa tcatatgttt caatttagta tgaatgtaga
     2581 tgttgtcgtt ccacctcatg gtaaaatggg agcagcaatg gcagctatga aaagagttag
     2641 accagataaa tatatattta caatagctgg agatggtgga gcttatgcaa tagggcttgg
     2701 agaaactatg tcagctgcta ctagaaatga taatgtaata tttcttgtta tgaacaataa
     2761 tatgtttgca atgacaggag ggcaaatggc tccaactact atagaaggtc aatatacagc
     2821 ttctactcca gcgggtagaa attacgcaga tcatggttca acatttgatg ttgtaaaagt
     2881 tatgggaaat ttagatatag catatctagc aagaggaaca ataactaacc ctaaagaaat
     2941 aaatacaaca aaaagataca tcaaaaaagc tctagaaaaa caaaaagaaa agaaaggttt
     3001 ttgcttaata gaagtgcttg taccatgtcc aacaaactgg ggattaaagc cagtagatgc
     3061 tatgaagaga attgaaaatg aacttgttcc aaagtatcca cttggagaat ttattgatta
     3121 gggaggaaat aatatgttga atgaaattat atgtgctggt tttggaggac agggagttct
     3181 tacagcagga aaaattataa tgtatgttgc atataaggca gaaaagaaaa ttacatggtt
     3241 cccatcttat ggaaatgaga tgaggggagg aagtgcaaat tgcaatgttg ttgtaagtga
     3301 tgaaaaaatt gcaaatcctt gtgtaaaaaa tccagatata ctattgggaa tgaacagcgt
     3361 atcagtagat aagtatgaaa gtttaatgaa aaaaaatggt tatatgtttg tcaatgaatc
     3421 actagtaagt aaggatagaa agtacagaga agacattaat gttataaaag tacctgttac
     3481 tgaaatagca caaaatttag gcaatgaaaa agctgctaac atttgcatgt taggtgctat
     3541 ggtaaagagt ttggatttat ttacaaaaga agaatttgaa agtggtatgt gtgaatactt
     3601 tgaaaatcaa ggcaaaggta aattcaattc taaaaatgta gaagcatttg aagctggata
     3661 cgactacgaa tgaatatttt aaatatttaa aataattatt gaaatactta tttttatatg
     3721 ttagtattta attaataaaa tatagaacgt cgttctggac aatgggacga agtctttagg
     3781 tcggaataca agaacggcgt tctgtataat agaactaggg ggtgttaaat tgaaagtttt
     3841 agtaataaat cctggtggta catccacaaa aatttctgtt ttccaagatg aaaatgaaat
     3901 tttgaaaaaa aatataaccc atacaagaga agatttaaaa aatttttcta aagtatttga
     3961 tgaatatgat tatagaaaac aactgatagt agatatttta agtagtgaga atcatagtat
     4021 aaattctttt gacgcagtag ttggtcgtgg tggacttatg aaggctataa aaggtggtac
     4081 ctatactgtg agtgaagaaa tgattgagga tatgagaaat gaaataaatg gggaacatgc
     4141 atcaaattta ggtgcattat tagctaaaac tatagctgat gaaataggag tacaatcatt
     4201 tgtagtagac ccagtttctg tagatgaatt tgatgatgta tcgaggatta caggaatatc
     4261 agacatagaa aaagcaagtt ggttacatgc attaaaccat aaagctgttt caagaaaaat
     4321 tgcacaaaaa ctagggggaa aatacgagga ttataacttt attgtagctc atttaggttc
     4381 aggaatatcg attgtagcac ataaacaagg caaaatgatt gatggaagtg gtggtaggtc
     4441 tgatggtcca ttttctccag aaaggagtgg tggattactt gcatatcctc ttatagaatt
     4501 gtgttactcc ggaaaatata ctcatgatga aatggtcgca aaagtaagtt cgattggggg
     4561 aatgtacgat tatttaggaa caaaggacat gatagaaatt gaaaacagaa tcaaggaggg
     4621 tgatgaaaag gcaaaactta taatggatgc atttatttat caagtagcaa aagaaatttc
     4681 tatgtatgga gcttcacttt cagggaatgt agatagagtt atcttgacag gagggatatc
     4741 tcactcagaa atggtagtca aaggagtagc agaaaaagtt tcatatctag ctccaataga
     4801 gatagtacca ggagagatgg aaatggaggc acttgctcta ggggcactta gagtacttaa
     4861 tggagaagaa atagcaaaaa cttattaata tttaggagaa agagtatgtt aaaagatttt
     4921 aataatttat tagaagaggc taaaaagctt gaacctgtta ttgtaagtgt tgctgttgca
     4981 gaagacaaag aagtattaaa ggctgtgaaa tcagcaacag atttaaacat tataaagcca
     5041 attcttgtag gagacaagga taaaatagaa agtatatcaa gagaaattgg attaaaaggt
     5101 catgaaataa taggttgtca aaatcccgat gaatcagtta aaaaagctgt agagatagtt
     5161 aaaaataagg aagctaaagt tcttatgaag ggattagtaa atacaagtgt ctatatgaga
     5221 gctatattaa ataaagaaac gggtcttaga acaggaagat tattaagttt gcttgcagta
     5281 tatgaattac ctcaatatca taaacttctt tattgtactg atagtggaat aaatgtatcg
     5341 ccaaacttaa atcaaaaaaa agatataatg acaaatgcac ttcttactat gaaaagtata
     5401 ggcatggaaa atcctaaaac tgcgatactt actgcaaatg aaatggtaga ccctaagata
     5461 caatctacag tggatgccaa cctacttgta gagatggaaa aatcgggaga aataccaaag
     5521 tgtatagtgg aaggtccaat agcatttgat gtagcatttg atgcacatgc agcagaacat
     5581 aaaggtatta aaagtaatat tgctggtgat gttgatttat tagtatttcc aaatatagaa
     5641 gcagggaata tattaggaaa gtcatggctt agatttaata aagctaagtg ggcaggtata
     5701 gttttaggag caacaaatcc gataatttta ggttcacgtt ctgacacagc tgaaataaaa
     5761 ataaattcaa tagcattagc gtgcctagca tcacaataag aaattattat taaggaggaa
     5821 aaagtattat gaaatatgca aaaagaatgg atatggtaaa agcttcagct ataagagatt
     5881 ctcaaaagaa aatagctcag aaggtagcaa gtggtggaac tgttatatct tttgctgcag
     5941 ggcttcctga cccaaattta tttccaatag aagagataag tgaaataact caaaaagtac
     6001 ttaatgaaag gggaaaattt gccctagcat atggacctac taaaggtgaa gatgagttgt
     6061 tagatctatt agtaaaaaga atgaaagaag aagaaaatat tgatacaaaa gcagaaaata
     6121 ttataataac tactgggtca caacaaggga tagcattaag tgctatgatt ttattagaaa
     6181 agggagatgt agtagttaca gaaaatccaa gttacttagg tgcaataaat gcatttagac
     6241 cttatgaatg tgatttttta ggagtagata cagatgaaga aggaatggta acagatgatt
     6301 tagacaaatt attatctgaa aattctaaca taaaggtgat atatgtaata ccaacatttc
     6361 aaaaccctac aggaaaaaca tggtctttac aaagaagaaa agattttatg gaagtcgtga
     6421 ataaatatga tgtcatagta atagaggata atccttatgg agaaataaga tttacaccag
     6481 aacctctacc tacacttaaa tctcttgata ctaaagataa agtattgtac cttgggtcat
     6541 tttcaaaggt attatgtcca ggatttagag ttgcttggat gtgtggtaat gtagacatca
     6601 tagataaggc agaactttta aaacaaggta tagatttaca gtcaaatcaa ttttcgcaag
     6661 tacaagtaat agaattttta aagaaataca acttaaatga acatatagaa aaaataagag
     6721 cagagtataa gaaaagatgt ctgctaatgt tagatgctat gaagaaacat ttcccagagg
     6781 aagctaaata tacagaacca gatggaggaa tgtttatatg ggttgaactt cctgaaagta
     6841 taaatgtaga tgatttatta gataaagcca ttgatgctgg agttgcttat gtttctggag
     6901 agtccttctt tgcaaataat ggtccaaaaa atactatgag acttaactat acaacaatgt
     6961 cagaagaaca aatcgttaaa ggtgttgaga tacttgcaga agttataaaa aaagaactca
     7021 attatgcttg tgaataaata taaaaagtga gggtttaaat atgggagaaa aagaaaacgg
     7081 tataaagttt ggaaagttaa tgtttcaact tgttattata gcaatatctt gggaattagt
     7141 ttatattata ccatttatcc aatatacatt atatgatcca atcctaaaag cattagaatg
     7201 tacaaacact caactaggtt ttctacttac aatttatggg ttaggtaata tatttggagc
     7261 tcctatagga ggctggttag cagatagatt tgattataga aagataattt taggttctgt
     7321 atttcttaat ggagtagtat catttttatt tgcatttaat atgaactatc catttgcagt
     7381 tgctacttgg gtaggttgtg caatcacatc attagttatg aactatcctt ctatggtaaa
     7441 aatacttaga gttataggaa aagataatca aggtaaggtt tatggattta atgaagctat
     7501 ggttggagtt tctggagtag taatgggagc aatattctta tatatttata catgctttgc
     7561 aactcctaca ttgggtatga gatgggtaat gatatcttta ggaatattat caatagcaat
     7621 gtgtccagta ttatggtttg taattaaaga tgtagatatt aaagaagaaa gagaagaagc
     7681 aggtgaaaaa atgtctgctg gtgattttat aacagtacta aaatcaccaa atacttggct
     7741 agtaggaata agtatattct gtgtatattc attcacagtt acaatgtctt attttacacc
     7801 atatataaca tctgtacttg gaggttctgt agcattatct ggtgcattag caataataag
     7861 acagcatggt ctaaaattat ttggagcacc atttggagga tattgtgcag acaaattaaa
     7921 atctcctaca aaagtacttt taccaatata tgtatttggt atagcagtaa tagttttatt
     7981 cctagtatta cctgcatcaa ctccaatgac tatattcata gctttaacat ttgtagtagg
     8041 tatattaggt tacatgggaa aaggtatata ttatgcagta caagatgaag taaaagttcc
     8101 agttaaatat tcagcaacta ctataggtat agctgcagct ttaggatttt caccagatgt
     8161 attccaattt gcattaatag gacactggat agatacttat ggcaataaag gttacacata
     8221 tacatttata ttccaaatag caattctagt tattggaata ctatcttgtt tatatatatt
     8281 aaaggttaaa aagagaagag caagtaaatt agaagcttaa atattcaatt tggtaattaa
     8341 gtatatataa atacaatact tattttgatg aatgtgattg tataaataac ataaaaaata
     8401 tcaatagatt aagttttata ataatgttta gagaataaag tataaaaatc aaaatgttat
     8461 caagttttct aggttttaac ataaagttac ccctgaaggt gtaaaattga gtggcaatta
     8521 ttatctattt tcttacctac ataaacctat ttaatttaaa ttctaagaga ttttcaaaat
     8581 agatggtagt tgtactcaat tttaaacctc ataataaata cgaaaattta aaatctaact
     8641 agatactatt taattatata ttaa
//
LOCUS       DAEPXW010000131         8644 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.135, whole genome shotgun sequence.
ACCESSION   DAEPXW010000131 DAEPXW010000000
VERSION     DAEPXW010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8644
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.135"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            248..1234
                     /locus_tag="KRM55_003287"
     CDS             248..1234
                     /locus_tag="KRM55_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1595494.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1571..3052
                     /locus_tag="KRM55_003288"
     CDS             1571..3052
                     /locus_tag="KRM55_003288"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBH1595495.1"
                     /translation="MYKEPKYRTILESTKEELNKLRSISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENNENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NDGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            3078..4049
                     /locus_tag="KRM55_003289"
     CDS             3078..4049
                     /locus_tag="KRM55_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBH1595496.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4305..4907)
                     /locus_tag="KRM55_003290"
     CDS             complement(4305..4907)
                     /locus_tag="KRM55_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1595497.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILDNSIEVDNC"
     gene            5188..6399
                     /locus_tag="KRM55_003291"
     CDS             5188..6399
                     /locus_tag="KRM55_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBH1595498.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKYNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6467..6664
                     /locus_tag="KRM55_003292"
     CDS             6467..6664
                     /locus_tag="KRM55_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBH1595499.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            6698..7669
                     /locus_tag="KRM55_003293"
     CDS             6698..7669
                     /locus_tag="KRM55_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1595500.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            7856..8233
                     /locus_tag="KRM55_003294"
     CDS             7856..8233
                     /locus_tag="KRM55_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1595501.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         3515 a          898 c         1369 g         2862 t
ORIGIN      
        1 tagccttatt tttatattat aaataaatta gagtatttat caattcatag tagataaaat
       61 tgaaattaaa tataacaaca aaaaatgaaa attacaatta atttaatgtt aaagactcaa
      121 ttatttggat gtggaatgga tagtacaagt agtatataaa aagtattgac tggacaaata
      181 actatatttt attttaaata tataatataa tgtaataaaa tatatcaaat gtagaaggtg
      241 ataacctatg aaaaaaataa caataaatga tattgctaac ttggcaggag tatctaaaag
      301 tactgtatca agatatctaa ataataaaga tatcagtgat tctactaaag agaaaataaa
      361 gacaataata gatgaatatg gatatgagcc gaatgcattt gctcaaagtt tgagagctaa
      421 aaaaacatac tttattggta ttataacacc gtgtttagat tcttttgtaa aatctaaaat
      481 tatgatggca atagatgaag aactcaaaga attaaaatat acatcactaa ttattaatac
      541 taatagaaaa ataaggtcag aaatagatag tatatcaaaa ttagctagtc taaaagttga
      601 tggaataata ctaattggta ccgaaataac taaagaacat aagaatgaaa ttgaaaagtt
      661 agatataccg atagttgtag ttggacaaaa agttgatggt atcaatagca tagtgaatga
      721 tgattatgga gcaggatata aaatgggtca atatattgct aataaaggtt acaaaaacat
      781 tgtatattta ggtgttgatg aaagtgatat atcagttggt ttaaatagaa aaaatggagt
      841 acttaatggg ttaaaagata aagggtatga tgcaaaagta ttttatactg actttgacca
      901 agaaacgtct atacaaagaa gtggagaaat gctagaaagt gaaaatccag atataataat
      961 atgtgcaact gataatatag caatagcaac aatgaaagaa atcaataaga gaggtaaaaa
     1021 tataccacaa gatatatctg tagctggatt tgggggatat gatgtattgt ctattataag
     1081 ccctaaactt acaacaataa agtttgaaaa taaaaatgca ggtaaagtag cagcaaatac
     1141 gatagtaaac ttaatacaag aaagaaaaga accactatta aaggagatta aatttgaatt
     1201 aatagaaggt gaaagtacaa taaataaaaa ttaagataca cattacatat attagtaatg
     1261 tgtatttttt tactaaaaaa actataattc taaaaattag gaaaactttt ttaaaagaaa
     1321 tattgcatct gaaataaatt tatgctaatc tttaattaaa ccggtttcga aaccggttta
     1381 attaaaccga tagaatagca aaatgagtgc aaaaataact gattgtaaca aagtatcaaa
     1441 gtaattattg gagtacatag gaaataaata aaatataaaa ggtgtagcac attgtgtaat
     1501 aagactaaga attgttttag atagcaataa taaagcaaat ataaaattat aaaagaaaag
     1561 gaataaaaat atgtacaaag agcctaaata tagaaccata ttagaatcga caaaagaaga
     1621 attaaataaa ttaagaagta tatctttaaa tgataaatat aaaccactat ttcatataca
     1681 tccacaacat ggactactta atgacccaaa tggattagca tattataatg gtaagtatca
     1741 tgtattttat caatggtatc catatgatgc aactcatgga atgaagcatt gggcttatgt
     1801 aagttctgat gattttgtaa actggaatag agaagatgta gcattaatac caatcgaaag
     1861 ttatgaatct catggagcat attcaggtaa tgcgatagag gtagatggaa aattgcatat
     1921 gtattataca gggaatataa aatatagtgc agaagataga tatgcatatc aaaacttagc
     1981 tataatgaac aaggatggta aaataactaa atatgaaaat aatccaatag taagtgaaat
     2041 accaaaagga tatacaggac atgtaagaga cccaaaagta tttaaaagaa aggataaata
     2101 ctttatgtta cttggagcac aaacaagtga taaaaaagga gttataatag tatatgaatc
     2161 taaaaactct atagattgga attttaaagg agaattaaat gtaaaaaaca tagatgaaga
     2221 ttttggttac atgtgggaat gtccagatta tattaatata gatgaaaaag atatattaat
     2281 attttcacca caaggagtag aacctaaagg atttgattat caaaatatat ataatgtagt
     2341 atatgctatt ggtaatatgg atttagataa tttaacattt gaaatagata caatgaaaga
     2401 actggaaaaa ggatttgatt tctatgctcc acaaacattt ataaaggact cacaaataat
     2461 actatttgca tgggctggaa tgggagaagt tttataccct acagataaaa acaaatgggc
     2521 acattgtcta actgttccaa gaaaattaaa tataaaaaat aataagctat tgcaaatgcc
     2581 tgtagatgaa ttaattaaat taagatatga tgaaacaagt gggcaaaata ctataaagaa
     2641 taatatcaat attatagaaa ataatgaaaa tgtatatgag cttaatatta atataaaaaa
     2701 tattgacagc aataaatttg ggctggaatt attttcatca caagatgaag gtgtaaaatt
     2761 agaatttaac aaattaggaa acattgtaac tttagacaga agcaacttta aaaaagtttt
     2821 cggtgttgaa tatggaacaa atagaaaaga atatataaat attgatgaaa atactaatat
     2881 caaagtacta gcggatagaa gtattttaga aatttttata aatgatggag aagtagtatt
     2941 tactagtaga atatttgcta aagaaaattc taatcaaata agggtttata gtgataaaat
     3001 agtagagtat gagtatacta aatttaaatt aaagcaaggt attgaattat aaaaacacat
     3061 tataaggggt agaaaagatg aaaaaagtaa ttagcatagg agaagcttta atagacttta
     3121 taccgaatca aaatggtggt aaattaaaaa atgtatcaga atttagaaga gtagcaggag
     3181 gagctccagc aaatgttagt gctgttgtag caaagcttgg aggaaaatca agttttatat
     3241 ctaagttagg aaaagatgca tttggtgatt atataataga tgtattaaat gaagtaaatg
     3301 taaatactga ttatgtattg agaacaagta aagcaaatac aggacttgct tttgtatcat
     3361 taaaagaaga tggtaatcgt gatttctcat tttatagaaa tccaagtgca gatatgcttt
     3421 tagaagctga tgaagttaaa aaagagtggt ttaataattg tcatatccta catttttgtt
     3481 cagtagattt aatagatagt ccaatgaaat tagcacataa aaaagcaata gaatacgcac
     3541 ttgaaagtaa tagtataata agctttgacc ctaatataag attaccttta tgggatagtg
     3601 agcaatcttg taaaaaggca atatcagaat ttttaccttt tgctcatatt gttaagatat
     3661 ctgatgaaga attagaattt ataacaggag aaaatgatat agaaaaatca ttacataaac
     3721 tctttgtggg gaatgttgaa ctagtattat atacaaaagg aaaagatgga gtagatgcat
     3781 acactaaaaa agtaaaaggt atgtgtaaag gggttaaagt aaatgcaata gatacaaccg
     3841 gagcaggaga ttcttatata ggttcatttt tatacacctt attgtataaa caaataacat
     3901 tgaatgatat aaaagaaatg aaacaagaaa cgttaaatga gtatttagaa ttttctaatt
     3961 attatgcagc tcgtagtaca actattaaag gtgcgataag ttcatatgca acaaaggaag
     4021 aaataactga atttataaaa aatttatagt aggaatgagt aataggtttt gaaggaagta
     4081 acatgtaaag agtttttaag gatgtttact atgaaaataa ttaacatata aaaagcaata
     4141 aagaggctgt ctcaaaatag agataagcct ctttataatt gttgaaatga taaaaaatat
     4201 tttaattatt gttacttttt agaagaatat atatcttatt ttaaataagc aaattatgta
     4261 agatttattt atattatcaa tactttactt ggagtattat gtctttagca gttatctact
     4321 tcaattgaat tatctaaaat ataataaatt tgttttgcaa attgacgaga atgttcttct
     4381 ttttctttat tcataaaatt aggtttacct aaatcacgtt caacaagcat tcctatatat
     4441 tttaactgtg aatgcttaca gtagcgcttc ataccatttt cccaaatatc agcacccttt
     4501 tcaggtctat atccacatgt tgtaataagt gctactggtt ttcctgccca tagagcgggg
     4561 cctttctcat taccatagta cttattcatt ccatacacca atctgtcaag tagtgctttc
     4621 attggagaag tgcagtacca agaataaatt ggagtagcaa aaacaattaa atcacacata
     4681 agaattttct tgaaaatttt ctgaacatca tctttacaat aacatccaaa atcaaataag
     4741 ttatcctgac attttttaca agcaatacat ggctctattt tacaatcata taaccatatt
     4801 acttcaatat ttgaattata attttctaat tcctcaataa aaggttttaa aatagcagca
     4861 gtattacctt ttttcttagg acttcccata agaatgcata cttccatatt gatacctcca
     4921 cagtatttta aaatagtttt tagtgcttaa tatagtttta ggatactatg agaatacgtt
     4981 aacaacaata cactttgtat atttgtaata aaattgaaac aaattgtttt atcaataaaa
     5041 gttggaatgt atctataatt aaaaatattt taggtatgtt tttacatata tgtgtgtagt
     5101 taactatggt aatttattgt aaaattatct tataggatta taattgctta atttatgatt
     5161 atatttaaaa tcttggaggt aaaaaatatg tactcaaatg aagactataa atttatagaa
     5221 gaaaatgcac catgttatat atatgatgag actaatataa ttgaaaaatg taaggaattg
     5281 aaaaataata ttttaggttt tgatttttta tattctataa aaacaaatcc atataacaaa
     5341 attgtaaaaa gcattgcaga gcaaggtttt ggagcagatg cttcttcaac taatgaagtt
     5401 atgatttcat cagaatgtgg agtttctaaa gatgatattt attattcatc accaggcaaa
     5461 acagagattg atatagaaac tgttttagat aaatgcataa ttattgcaga tagtattaca
     5521 gaaatagaac ttataaataa gatatctaaa aagtataatc agaaagttaa aataggaata
     5581 agaataaatc ctgattttac tatggatgat gatagtgcta aatcaagcaa atttggtata
     5641 gatatagaag atatgagcag tgtttttaag atgttaagta tgtgtgatta tgtatctgta
     5701 gttgggattc atatacatat taaatctcag gtattggatt ttgaaaagtt aggacattat
     5761 tatgaaaaat gtttttttat agctttaaat ttaaataaaa gtaagtatat taatattgaa
     5821 tttataaatt ttggtagtgg acttggagta gcttatgata atcttagaga aaatccactt
     5881 aatcttaaag agctttcaaa attaactcaa aagattgctt ttactaattc aaacacacta
     5941 aaatcaagac ttcttattga atcaggacgt ttcatagttt gtaaatcagg taattattat
     6001 gttaaaattg tagatattaa agtatcaaga gggaaaaaat atcttattgt aaaaaatgga
     6061 cttaatggat ttatgagacc tattatttct aatttaattg aaaatattac ttgtggagta
     6121 gaattagaag gtcaagagcc attatataca tcaaatcatg ccttttctct ttcagtatta
     6181 aataatttaa aagaagaaga gtatgtaaat gttgttggga atctctgtac atcattagat
     6241 gtaattgcaa ataatgttaa attgaaaaaa gcaaacatag gagatttgat ttcaattagt
     6301 aatgctggaa gttactccta ttctttatca ccgctattat tttcaagtta tgaatttcct
     6361 aaacaatatt ataaaagaaa agatggatat attgagtaaa caatagcata aattaataaa
     6421 cttagtatta ttgaaaaaat ttaaaatgca ggaggtgtaa ttctatatgg aattgtggaa
     6481 aagaaattta tttgtatgtt ggataggtat gttttttagt tctataggga tgagccaaat
     6541 agcacctata cttccattat atattaaaca gttgggggta actgatgtta gtttaataca
     6601 acagtattca ggtataattt ttggatgtac ctttgtagta gcagcattct tttcgccaat
     6661 ttgagggaaa gctgctgata aatatggaag aaaatcaatg cttttacgtg caagtattgg
     6721 gatgggaata gttatattta ccatggcgtt tgttcaaaat gtctatcagt tattaggatt
     6781 aagaatactt caaggagttt ttacgggtta tgctactgca tgtactactc ttattgcaac
     6841 acagacagat aaaaatcatt caggatgggc tttgggtact cttgcaactg catcaactac
     6901 tggctcatta attggtccaa cagtaggagg atatatagaa tcaatcttag gtcttaaaag
     6961 tacatttatt ataacaggag gattgttgtt tgtatcattt atcatctcta ttttatttgt
     7021 agtagataat tttaaaccta aagaaataaa agaatcaatt tctataccta aagaacaatt
     7081 aaatatattg ccaaataaat ttttaattgc atctattttt gtaaccacat tcattactca
     7141 actagcttta tactctatag aaccaattgt aaccatatat atatcacaac ttacaaattt
     7201 tgcatcaaat gtagctttaa tagctggatt gacattttct gcatcaggat tagcaaattt
     7261 attagcagct caaaaacttg gaaaaatgtc ggataaaata ggtcctcaaa aagtattgtt
     7321 aatttcactt ttatgggctg ggattatatt tataccacaa gcttttgtaa aaactgcatg
     7381 gcaactgatg ttgttgagat ttttattagg gttgtcagtt gcagggctta atccttctgt
     7441 taacagcttg cttaaaaaaa ttgcaccaga agaatatgtg ggaaaaatat ttggatataa
     7501 tgcatctgcc cagtatatag gttgttcatc aggagcattt ttagggggac aaatatcagc
     7561 acatttaggt attagaacag tatttttttc aacaagttta ttgttgttta tgaatgcact
     7621 ttggatgtat aaatttactg gattgtttat taaagataag actaaataat catactattt
     7681 acatttctaa ttttatgatg taaaataaat attttttatg taatttatca tagaattata
     7741 taaaaaataa ccctatggta aaaattggaa aatattatta ttgacaaaat ctttgactta
     7801 aaaactatat tgcgatagta ttaatttaat aaaagtttga gaggggcgta aggttatgac
     7861 aatttcaaaa ataccacaag cagaattaaa agttatgaag tttatttggg aaaaaaatga
     7921 tacagtaaca tcaaaagaaa ctattgaagc tatggaacga aaatatggtt ggaaacaaac
     7981 aactacattg acacttttat caagacttgt taaaaaacat tttttaagtg cagaaaaaat
     8041 agatagatac actcattata caatagttgt tggacataag gagtatttaa gtgttgagac
     8101 aaaagatttt ttaagcaata tacacgacaa ttctttacag agtttaattt cagcactaca
     8161 tgatgatgaa gttgttgata aagatatgtt ggatttattt gaaagtcatt ttaaaaattt
     8221 agaagaagag taattatatc aggatagaac tctaagaatt taattaatct atggctgaaa
     8281 accataaatg gtattattta atcagctact cactattcat aaagtaatat taaataggtt
     8341 ctctaattag taaaatgcct aaaataattg gaatagggag tatcaagtta aatgatacca
     8401 cttatttaaa taagaaatga tttttaaaat ttaaaataat tttataactt gtcaatattc
     8461 attaatctaa agcattattt ctatttaacc atatcaaaat atattttact atttttaatt
     8521 attacaatat aaacctgtct tttgttatta taggtaaact aaaagtaaga aataattttt
     8581 atatttttaa actttattat tggtaactta tctgtaaata ttttaaaatg tactatagaa
     8641 agtt
//
LOCUS       DAEPXW010000132         8637 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.136, whole genome shotgun sequence.
ACCESSION   DAEPXW010000132 DAEPXW010000000
VERSION     DAEPXW010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8637
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.136"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(12..908)
                     /locus_tag="KRM55_003295"
     CDS             complement(12..908)
                     /locus_tag="KRM55_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1595502.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASHVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHKEVSNVILKEDMK"
     gene            1049..2476
                     /locus_tag="KRM55_003296"
     CDS             1049..2476
                     /locus_tag="KRM55_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1595503.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(2672..5266)
                     /gene="clpB"
                     /locus_tag="KRM55_003297"
     CDS             complement(2672..5266)
                     /gene="clpB"
                     /locus_tag="KRM55_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBH1595504.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5303..5899)
                     /locus_tag="KRM55_003298"
     CDS             complement(5303..5899)
                     /locus_tag="KRM55_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595505.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(5916..6320)
                     /locus_tag="KRM55_003299"
     CDS             complement(5916..6320)
                     /locus_tag="KRM55_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBH1595506.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            6687..7061
                     /locus_tag="KRM55_003300"
     CDS             6687..7061
                     /locus_tag="KRM55_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1595507.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7058..7921
                     /locus_tag="KRM55_003301"
     CDS             7058..7921
                     /locus_tag="KRM55_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595508.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            7921..8559
                     /locus_tag="KRM55_003302"
     CDS             7921..8559
                     /locus_tag="KRM55_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH1595509.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT         2891 a         1274 c         1007 g         3465 t
ORIGIN      
        1 atatttatga attatttcat atcttctttt aaaataacat tactaacttc tttatgttca
       61 tttctatact tagttggaga tatattataa ttccttttaa ataagcgact aaaataattt
      121 atgctatcaa agccacatct catagcaatt tctgtcatat ttaaatctgt ttcctttaaa
      181 taatatatag ctttatcaag cctgattcca tttataaaat cgattgtagt cttacctgtt
      241 atttgcttaa atgttctaca aaagtgatgt gcactcaagt tcacatgact agcaagttct
      301 tttaatgtaa ttttatccat atatttttct tctatcaaat caaagataca ttcaaatttt
      361 tctaaagaat actttctttt tataaattca tcttcagaat atattttatc aatatgactt
      421 cttaataaga gtactattaa ttgatagata ttagctttta tagataactc atatccaact
      481 tctttattgt gatattcatc aagtatagtt gtaatacatt ttaaaatcag agaatcattt
      541 tgaattaaat tattaaatac aatatgattt aaagccaatg gtgctaagta cttggtttgt
      601 aacaaatcaa cttgattact aaaaaggaat gtgggttcaa tacgaatact atagaatttt
      661 aaattatctg ataagctttc taaataatgt aattcattac tgtttgctat tacaatattt
      721 ccaggcacta ccttaaaatt atccaatcca cattcaagat atgctatacc atcaataaaa
      781 taatatattt gtagatgctc atgccaatgt cttttaaagt ttgctccttt tttaatgtca
      841 tcctttaaaa aaatatctat aaagttttct tgacctttcc tgttaaaata tgtattttta
      901 tccttcatta ttcccccctc atcaaaatag tgctaattat aagcaatata gttattgtat
      961 tcattatttc atatcgctat tatataaaat gtaactatca ttgtaaacat taacataatg
     1021 cagtcattat aataaggagg taataaaaat gacaaactct tttaaaaaag atgataatag
     1081 aaaaaaaatc acagttttat ttgtagtcat tgccatgact tttatggcaa cattagattc
     1141 tagtattata aatgttgctc tcccagttct tgcaagcaaa ctaaatgtat ctctagcatc
     1201 tattgaatgg gtaatagcaa gttactcaat tattatttgt tcaacactat tattttttgg
     1261 aagacttgga gatattattg gtaaatcaag agtatttcaa gtaggtacta ttctctttac
     1321 atcagcttca ttactatgtg gattaagtaa ttctttaact ttacttatag tttgccgctt
     1381 tattcaagga ataggcgctt ctgcctacat ggcaaacaat catggaatta tcacagaact
     1441 atttccaaaa gaaagcagag gaaaagccct agggatttta gttactgcag ttgctattgg
     1501 aaatatggtt ggaccatctg tgggaggatt tattttgtca atatttgatt ggaatgttat
     1561 attttttata aatattccaa tcggtcttat tgtaatcttt ttaaatacaa aatttcttcc
     1621 taatagtaaa aaatcttcag aaaatatgga taaaactggt gctatacttc aatttttagg
     1681 aacaacatta ttttttagtg ctctaattag tgctcaacaa acaggattac taaatccata
     1741 tatattaatt gcactattat tatcaattat ttttattata ttatttttga tattagaaaa
     1801 aaaacatcct caaccgcttc ttgaccttga aatttttaga aattttaaat tttcattgaa
     1861 tttaatttgt gctcttacat cattcatttg tattgcatca tcaagtattt taattccatt
     1921 ttatttacaa agtactatga aacttccccc tattcaagca ggtttattta tgatactatc
     1981 acctttgatt ttagccattt tttcacctat atttgggaat atatcagata aaattaagtc
     2041 agaaaaaatt attttaattg gtcttctcgt tatgagtttt ggattctttc taatgtcaag
     2101 attgaaagaa agttctgccc ttattttatt tgtaatttat atatcgataa tatcaatagg
     2161 acaagctata tttcaacctg ctaacaatgc tttgataatg tcaagctgtt ctagaagtaa
     2221 gctaggagtt gtaggaagca taaattccct tgtaagaaat ttaggacaag ttataggtat
     2281 tactatttct acaacacttt tatataattt tatgagtatt aaagctggat atagggtcaa
     2341 tgattatgtg attaataatg ataaaatatt tgtatttgga atgagaaatg tttatattat
     2401 tgttacactt gtttgcttaa taggtgcaat attaattggc ttttatttat ttaaatataa
     2461 taaaaatgaa caatagtttt tataattata ttcaaattat gattatatta taagaaattt
     2521 actaaaatac ttcctttgag ttaaatttaa tttggacata ttgacttaaa aatgttttat
     2581 taatttgata aaatatttct tttcctatag tttataaata aaaatcagct gagcaaaata
     2641 tttagtatat tatgctcaac tgattctttt attatttaac taaaacttca atattttcat
     2701 cttttccatc tataactata gtacatccat tatacacatc tccagcaata agtttctttg
     2761 caattatagt ttctaatgta tttcctatat atctcttaag aggtcttgct ccatatacag
     2821 ggtcatatcc ttctctcacc ataacatctt ttgctgaatt tgtaacttca atagtaatat
     2881 ctttttcttt taatctattt tttaaatctt tcataaatat atctataatt ttcttgatat
     2941 tttcttggtc taaaggctta aacattataa tatcatctac tctgtttaaa aactcaggtt
     3001 taaatctatg cttcatttca ttcattacta aattgttagt agtctctgtt atatttcctc
     3061 ctgcttctaa tagataatta cttcctatat tagaagtcat tattataaga gtatttttaa
     3121 agtctactgt cttaccttta ttatcagtaa gtctaccatc atctaatatc tgtaagaaca
     3181 tgttaaatac atcctcatgt gctttttcta tctcatcaaa tagtattaca gaataaggag
     3241 cacgtctaac tgcttctgta agttgaccac cctcttcata tcccacgtac cctggaggag
     3301 gtccaactag tcttgataca gcatgttttt ccatgtattc agacatatct attcttatta
     3361 tattatcttc actatcgaat aaatttctag caagagtttt tgcaagttca gttttaccaa
     3421 cacctgtagg gcctaagaaa ataaatgaac caattggttt tctttcatct tttaatcctg
     3481 ctcttgcacg tattactgca tttgaaactg ctgtaactgc ttcatcttgt ccaataactc
     3541 ttttatgaag ttcatcttct agtttaagta atttttctct ttctccttca actagtttag
     3601 ttactggtat acctgtccac tttgatacaa tgctagatat ttcttcttca gtaacttctt
     3661 cttttaaaag agaattttca gaaccatcat tcatattttc ttcgtactgc tttatttgtt
     3721 cttctaactt aggtatttca ccatatttaa cctctgctgc tttgttgaaa tcatattctc
     3781 tttcatactt ttcagcttta cctttagctt cgtctaattg agcctttaag tttttaatat
     3841 ctaatatttg actcttttct ttttcatatt ttgctgtcat ttcatcattt ttagatttta
     3901 actctgctat ttctttttga atatcatcca atcttgattt acttttatca tcattttctt
     3961 taagtaatgc ttctctttca gtttctaatg taaataactt tcttctaaca acatctaatt
     4021 ctgttggcaa tgaatctatt tcactacgaa tcatagctcc agcttcatca attaaatcaa
     4081 ttgctttatc tggtaaaaat ctatcttgta tatatctatg agaaagtttt gctgctgcta
     4141 caatagcatt atcatgtatt cttactccat gatgtatctc aaatctttct tttaaacctc
     4201 taagtataga tattgtatct tcaacagtag gttcttctgc aattacaggc tgaaaacgtc
     4261 tttcaagagc cttatctttt tctatatact ttctatattc atcaaaagta gttgcaccaa
     4321 tacagttcaa ttcacctctt gcaagcatag gtttaataag attacctgca tccattgaac
     4381 cttctgtttt accagctcca acaatagtat gaatctcatc tataaacagt ataatttttc
     4441 catcagaact ttgaacttct tttaaaactg cctttaatct ttcttcaaat tcacctctat
     4501 attttgcacc agcaattaaa gctcccatat caagtgagaa tacaatctta tcttttaaac
     4561 cttctgggac atctcctctt actattctct ctgctaaccc ttctacaatt gcagttttac
     4621 ctacacctgg ctcaccaatc aatacaggat tattttttgt tcttcttgat aaaattctta
     4681 taatccttct tatttcttca tctctcccaa ttacagggtc taatttattt ttcttggcta
     4741 aatctactaa atttgttcca tatctagcaa gtgcatcata tgtgccttct gggtcttgtg
     4801 tttctactct ttgactacct ctcacttgtg ataaaatatt taaaaagtca ttcttattta
     4861 tattatattg ttttaatatt ttaccaacag ctgattttga ttctgtttcc atcattgcaa
     4921 gcataacatg ctctacactt atatatgaat ctttaaattc tttagaaata ctctctgcct
     4981 ttataagcac ctcatttatt tttctagtag ctgatactcc ttgtgagtca gcaccttctc
     5041 catatacttt tggaagctta tcaatttcaa agtttacagt atttctcaaa gaatcaattg
     5101 atatattcat tttttcgatt atatttggta tcaatccatc ctcttgatta ataagtgctg
     5161 agaaaagatg aattacatct acttgttggt tatgattttt tactgcttcg ttataagcct
     5221 catttaaact tttttgaact cttaaagtca ttttttctac gtccatataa atccctccat
     5281 tttaatatta tatccaaata aattaaattc tctcatttat aattattgat tttctaagct
     5341 ctaaaagact atcaagtaaa ttctcgtttt tttgtatatc gaaactcaat gttaaattaa
     5401 atgttccatc tgaattaaaa aaatcgaata cttcttttga ttttgctatt aaatacaagt
     5461 cttcatctat aagtcttttt tcacctatta ataaatactg acatttatct ataaaactct
     5521 ttttaaaatc aatagtgtat agattttcta aaatattata ttgataaata gcaatattat
     5581 taaacacttt taatatgttt gaatttacaa aattgtaaat ttgattattg ttatacagtg
     5641 atatttgttc gtatatatat tccctaaata aaggatgaat gttttgctta agttttaaag
     5701 taacttcagc tggtatttca aaataaagct tccagtactt agagttattt ttttctaaaa
     5761 taaaagctac tttgttcaaa ctggtagaac taatctcctt tagtgtacaa ttaaaattat
     5821 agtgtctcaa actagttttt tcattctcaa atacatagtc aaaccactgt agaacatttc
     5881 tatcaagttt taaactcata taaaaacctt cttccttatt tactaacctt attaggtctt
     5941 tttatctgat tatattctgc taataaactt tctttatcag ctctactacc tttatatgct
     6001 atatgtggat ttatcatata ctcaccattt ttcactcttt gtaaaaaatc catttttttc
     6061 agctccgtaa acaatgaaga taaagaagtt tttggatatt caaattcaca agataattca
     6121 tataatgttt ttctaatctt attattttta tccatagagt ttattaattt taatggaatt
     6181 aaatccctct tagtatacat tccttctact actttaatat aattcttaaa acaaacattc
     6241 atatacttac ttttattcat aactaaactt ttgctctctg tatattcctg atttaaatcc
     6301 ttttttaatg tcttatccaa attaaatatc tcttctcact ctccttatct ctaattgata
     6361 atataaatat attacaaaaa aatatgtatg tcaaaactga aaatgcaaaa agttcacctt
     6421 ataagcaaac ttttatttag ctataagcta aactttatta tttttttaat ttagtatttc
     6481 caatttattg gcaggatttt tgaacaatat ttataaattt tttaaaaaaa tttaaatcta
     6541 tttaatatgg cagactttca taaaatacat tacatttatt aaatgtataa tattggcaat
     6601 tagttttttc taaaatcagt tgacatatta tatatatatt tatataatgt gtatatacta
     6661 tatatacaat ttaaggaggt gtcttattga atatagttat tagtaattcg agtgggaagc
     6721 caatatatga acagattact acacaaatta aaagtatgat tataagtgga gagttaccag
     6781 aaggctcagc tcttccaagt atgagactat tggcaaaaga acttagaata agtgtaatta
     6841 ctacaaaacg agcatatagc gatttagaac gagacggatt tattgagaca gttactggta
     6901 aaggcagttt tgtatctagt aaaaacatgg attttgtcaa agaagaacaa tttcgtttaa
     6961 ttgaagaata cctacaaaaa gcagttgata cagcaaaaag tagtgatatt acatatgacg
     7021 aattaaaaga tattttattt ttattatata aaggagaatg ataagtatgg atgcaataac
     7081 tataaaaaat ttaaataaaa cttataaaga ttttagccta caagatatat ctttttcagt
     7141 accaaaaggg agtgtaatgg gatttgtagg tgaaaatggt gcaggaaaaa caactacatt
     7201 aaaagcaatt ttaaatttaa tatcttatga tagtggaaat atagaaatct ttggtcttga
     7261 tagtaaaaaa aatgaaaaag aaattaaaga gcaaattggg gttgtatttg agggaagcaa
     7321 ctttcatgaa aatttaaaca ctgaccatgt ttcaaaaatc atgagtaaaa tctataaaaa
     7381 ttggaatgac accttattta aagactactt aaaaaaattg agagtaccag acaataaatt
     7441 aattaaggag ttttcaaagg ggaataagat gaaacttagt attgctgtag ccttatctca
     7501 taaaccaaaa ttattaatac tagatgaggc aactagttca cttgacccta tcgttcgtga
     7561 agaaatacta gatatatttt tagattttat acaagatgaa gaacactcta ttatcttatc
     7621 ttcacatatt acaagtgatt tagataagat agcagactat attacattta tacataaagg
     7681 aaaaattgta tttagtgaaa ataaggatga attaattgat actatgggag ttttaaaatg
     7741 taaacctagt gattttgata acctttcaag agaggattat tcatattatc gtaaaagcca
     7801 atttggatat gaagtacttc ttaaagataa acatagattt atctcaagac atccaaactg
     7861 tattgttgat aatacgtcta tagaagaaat tatgttattt tatgtgagag gtgataaata
     7921 atgaaaggtc taattttaaa agatttactt aatttgaaag gaaatataaa gtttatactt
     7981 ttattcatca ttatgtttgg ctttatgtct tctttaggag atggaaatgt taataacttt
     8041 ataggtgtta ttatagtttt atgtactaca atgattgttt caacattttc atatgatgat
     8101 ttgaataaat gggatagtta tgtacttaca atgcctatta atcgcaatga tattgtatta
     8161 agtaaatatt taactatgtt aatatttagc tttataggtg ttcttgtttc acttattgtt
     8221 agtgtaacta ttggttattt taaaaataca cttatattaa atgaaacact acttattaat
     8281 gcactaatct tatcaatttc agtatgtttt ggtagcctta ttctaccact tatttataaa
     8341 tttggtacag aaagagctcg tttattaatg attttatgct ttttagttcc aacactagct
     8401 ttattagttt ttaaaagtat tttagaaaat attagttcac ctatttctat agaaattata
     8461 cttaatacac tagtatattc tcttccattt gttgctattt tactatttgt gatttcatat
     8521 tttatatcat caaaaatcta tagtaaaaaa gaagtataaa atatactata tatatttctg
     8581 tatttaagta tttaaataaa atactatcga gtttattttg gtagtatttt atttttt
//
LOCUS       DAEPXW010000133         8570 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.137, whole genome shotgun sequence.
ACCESSION   DAEPXW010000133 DAEPXW010000000
VERSION     DAEPXW010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8570
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.137"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..248
                     /locus_tag="KRM55_003303"
     CDS             <1..248
                     /locus_tag="KRM55_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595510.1"
                     /translation="FKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIV
                     IIAFLATGNLNISLKKNKCKANTKNKSEKRGVVDVTN"
     gene            235..990
                     /locus_tag="KRM55_003304"
     CDS             235..990
                     /locus_tag="KRM55_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1595511.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            1121..2143
                     /locus_tag="KRM55_003305"
     CDS             1121..2143
                     /locus_tag="KRM55_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1595512.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKDKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(2307..2864)
                     /locus_tag="KRM55_003306"
     CDS             complement(2307..2864)
                     /locus_tag="KRM55_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH1595513.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2870..3946)
                     /locus_tag="KRM55_003307"
     CDS             complement(2870..3946)
                     /locus_tag="KRM55_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBH1595514.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTGGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRSKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3947..4630)
                     /gene="modB"
                     /locus_tag="KRM55_003308"
     CDS             complement(3947..4630)
                     /gene="modB"
                     /locus_tag="KRM55_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBH1595515.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4779..5591)
                     /gene="modA"
                     /locus_tag="KRM55_003309"
     CDS             complement(4779..5591)
                     /gene="modA"
                     /locus_tag="KRM55_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1595516.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5784..6713
                     /locus_tag="KRM55_003310"
     CDS             5784..6713
                     /locus_tag="KRM55_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595517.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6874..7323)
                     /locus_tag="KRM55_003311"
     CDS             complement(6874..7323)
                     /locus_tag="KRM55_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595518.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARVLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7526..8506)
                     /locus_tag="KRM55_003312"
     CDS             complement(7526..8506)
                     /locus_tag="KRM55_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1595519.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         2988 a         1404 c         1030 g         3148 t
ORIGIN      
        1 tatttaagaa atttactttt atcaaagata ctactgcaat aattgttggc tcttttatat
       61 accaattcac tatatacttt gcaatgagtt taggaatgtt atcaactgac ttaaaactaa
      121 taactgccat agttataata gctttcctag ctactggtaa cttaaatatt tcactaaaaa
      181 aaaacaaatg caaagctaat accaaaaata aatcagaaaa aagaggtgtt gtagatgtta
      241 caaattaaaa atctttcaaa gagtttccct aatccatatg gtgaacctaa tactatcttt
      301 gaaaatttat caatcgatat agaagatggt gaatttgtaa gtatcatagg tagtaatgga
      361 actggtaaat ctactttatt aaatataata tccgggctta taaaagaatc ttctggtcaa
      421 gtattattaa ataaacataa cttgtctaat ttagctgaac acagaagaac tcaaatagta
      481 agtagagttt ttcaagaccc aagtcttgga acttgccctt ctatgactgt tagagaaaac
      541 ttgtctttag ctcttaacaa aggaaaacta ttaaatctaa gaaaatgtct tcgttacaaa
      601 agagatttct tagaaaattt attggaaggt gtatctcttg atttaaaaaa ataccttgat
      661 gttcaagtaa aatttttatc aggaggtcaa agacaatcat tatcactaat tatgtcgtgc
      721 ttaacaaatc catcagtttt attacttgat gaacatacag cagcacttga cccaaaaaca
      781 tcaaatgaag taattgaatt gactaataag attgtaaggg aaaaaaatat aactacactt
      841 atggttactc acaacttaaa acacgctctt cattatggtg atagattgat aatgcttcat
      901 aagggtgaag ttgtattaga tgtaaaaggt aaagaaaaag aacaattaac agttgaagaa
      961 atcttagaaa aatttgaata tgcagtttaa aataatatat ctattgtatt aaactcggct
     1021 ttaaaataaa gttaaaatta caataattat ggttactttg taataattca tatgaatata
     1081 tgaacatata taataataaa tttttgaggg ggatataaaa atgattaata aaaaaagatt
     1141 ggcaagtttg attttagctg gtgctcttag tatatctatg cttacagggt gttcacaagg
     1201 aggagactct ggtaattcaa aacaagaaag taattctaaa gataaagaag ttaaaaaaat
     1261 tggtataact caactggttg aacatccagc attagatgcc actaggacag gttttgtaaa
     1321 agcattagaa aagaacggat ttaaagatgg agaaaatatt gatatagact tccaaaatgc
     1381 tcaaaatgac atgcctacta cacaaagtat tgcgagtaaa tttgcatctg ataagaagga
     1441 cttaatattt gctatatcta ctccatcagc tcaggcagca tttaatgcta ctaaagatat
     1501 acctatactt attactgctg tgagtgaccc tgttgctgct ggattagtta aaactcttga
     1561 aaagccaggc acaaatgtat ctggaacatc agattttgtt tctgtagaca aaggtttaga
     1621 acttcttaaa atatttgctc ctaaggcaaa aactatagga gttatgtaca atactagtga
     1681 agtaaattcc aaagttcaag ttgatgcttt aaaagaatat gcatctaaaa atggatttaa
     1741 agttgttgaa aaaggtataa ctacttcaaa tgaagttaac caaggtattt ctagtttagt
     1801 tggcaaaata gatgtattat atgttcctac agataactta gtagcttctt ctatgcctat
     1861 agtctctaaa atagctactg agaataaaat acctgttata gcagctgaat ctggtccagt
     1921 tgaaaaaggt gctcttgctt gtcaaggtat caactacgaa aaactaggtt acaaaacagg
     1981 tgaaatggca gttaaaattt taaatggcga atcagtatct gatatgcctg tggctacatc
     2041 agatgataca gatatcattg ttaatgaaga tatattaaaa gctttaggta tggaaaaacc
     2101 ttctaatgaa aatatttctt atgtaaagac taaacaagaa tagaaagata ttttctatat
     2161 acgattaata tgcctgtttc tataaattaa tttatagaaa caggcatata tttttatttt
     2221 aatgtattat ctatttaaag attatatgta aatgctctta atttgattgt ataaatttta
     2281 cttgtataaa ctttatacaa tcatatttat tcttctattt tctttattac tctacatgga
     2341 tttccaacag ctacagtatt tggtggtata tcttttgtga ctacacttcc tgcacctatt
     2401 actacattat cacctatagt aattcctggt gttatgatta ctcccccacc tatccataca
     2461 ttatcaccta tttttacagg agaaccatac tctatgcctg aatttctaag ttgtgcatca
     2521 attggatgat aggctgtata gatttgaacg tttggagcta acattacatt gtcacctatt
     2581 tcaattttac atacatctaa aaaaatacaa tcataatttg caaagaaatt ttcgcctaca
     2641 tgtatgttat atccataatc acacctaata ttttgttcta catttatttg cttgccaact
     2701 gaaccaaata gttgtcttaa aatatcttct cttttttcat attcatcctc taaagtatta
     2761 ttaaacaatc tagttaattt tttacaatac tctctttctt ttactaacaa ttcatcattt
     2821 gcatagtatc ctttcccaga caacattttt tctttttcag tcatatagtt tactcctttt
     2881 tgttataatt gtatctaaag caaaataaat attcctgtgg aaaatctaaa tatattctgt
     2941 cacctttctt aaatctcatt ttactttttt ccaattctat ttgaataggt acacattcgt
     3001 tagataaatc agtttttcta acatatatag tatatgtaaa aggattttct acaatgttaa
     3061 tcaattcgaa acataacttt tcatttaaat cttcattaga atccaagacc ttaatatgat
     3121 gctccctgat tcccacatat tctatattat cacctatttc tctatttaat gtcaactcgc
     3181 atccccagtc tgtagcataa atagtatttt tatccagtct atttaatttg gatatatttt
     3241 tacaccctgt tatcttagct tctataaggt actttggaga ttcaaagagc tcttttttag
     3301 atctctttgg aagaccttct cctttgttgt acactataat atcatcacaa actcggtaag
     3361 cttcttcaat atcatgagta acaaatagta tatctccctt gtaatctttt aacatattca
     3421 taagttcttt ttccatattg cttcttaaat gatggtccag tgctgagaaa ggttcatcta
     3481 aaagtaatat atctggagat gttgccaatg ctctagctag tgctaccctt tgttgttgac
     3541 caccagataa ttgccaaggg tatctcccct caaacccatt taatttaagt atatctaagt
     3601 accttgctac tatttccttt ttttcactct tacttagttt taaaagccca agttctatat
     3661 tttgacttac agtcatatgt ggaaacaaag catagttttg aaataaaaat cctacctttc
     3721 tatcttgtgt tgataaattt atcttctttt cagaatcaaa tagaactcta tcatttaata
     3781 caattttacc tcctgttggt ttctcaagcc ctgctataca ttttaatgtc atactttttc
     3841 cagaaccaga ttctcccaaa aaccccagag tacctttttc ttgtttaatt tctaccttta
     3901 gtttaaaaga ggataaatct ttttcaatat ccacgtataa gctcaactat ccacacctct
     3961 ttcctataat tttctgctga aattccgacc aataatttag taataaaatc attgctatag
     4021 atattgctac aataatcata acccacatca tagctttatt catatctccg ccttcaacag
     4081 caaaaaatat agctattggc atagtttgag tttttccagg tatatttcca gctatcataa
     4141 gtgtagcacc aaattctcca agagctctgg caaacgacag caccaatcca ccaattattc
     4201 caggccatgc taatggaact gcaatcttaa aaaatacttt ccattcatta agacctaatg
     4261 ttctagcagc tgacaacata ttattatcaa tctgttcaaa agctgacctt gaagttctat
     4321 acatcatagg aaaagacacc actactgctg aaattacagt tgctgtccaa ctaaatatta
     4381 aagtcctatc gaaatttaat aaaaactttc ctataaatcc attcttccca catagtaata
     4441 ataaaaagaa acctacaact gttggtggca aaattagtgg aagtgtaaat agtccatcta
     4501 taagaccctt ccacttacct ctatagttag ccataatata tgacacaaat attcctatta
     4561 caaaagttat tattgttgac aaaatagatg tcttaagtga tatccataag ggtgaccaat
     4621 ctgttcccat ctttccctcc ttaattttaa atggaaatag tgaaactaat aactctatta
     4681 atttcactat ttccatttta ttataataca caattatttt caattttcat ttatttatat
     4741 ataatttata cttaattaca cataatttat ttctaagttt attctacttt tttatatcca
     4801 aattcttcaa aaatcttttg tcctgactca cttaataaaa attcttcaaa tttcttagca
     4861 gcatctacgt ttttactagc tttaattact gaaactggat atgtaatagg cgaatgagtt
     4921 ttttcgtctg ttttttcaac tacttttatc ttatcattat tgacagtatc actgaagtaa
     4981 acgaatccaa catcagcatt tcctgattgc acccatgcta aaacttcttt tacatctttt
     5041 gcaaatacta gcttatcttt taacttatct tttaaattta aattagttaa cacctcatct
     5101 gcatacttac cagctggaac actttcagct tcaccaacag caattttctt cactttatct
     5161 gtagtcaaat ctttcatacc tgatacacta ctgtcagcag aagaaataag aactaaatca
     5221 ttttttacta aatctttcat agtatcagaa actaataact tctcttcatc caaagctttc
     5281 atttgttttt gacctgctga aataaataaa tcacaaggtg ctccttgttc tatttgttgt
     5341 tgtaatgagc ctgatgctcc atagttaact gtaagtttta catttgaatc aactttttta
     5401 tattcttctt caatctttgc cattgcttct tttaaacttg cagcagccga tatatttaac
     5461 tctactgaat cactactttt agttgttttt tcttgttttc catcatcttt tttgtcttca
     5521 ttactattgc acccaactgt ccccaaagtt aaacatgcaa ctaatcctaa tattcccaat
     5581 atttttttca taacaatctc cctttttgta aatttgatac acattttaac atgttttatt
     5641 atgttttatc atgttttgtt atatatagtt taattatata tacatgataa taaattttca
     5701 agtaatttat ttacactact tttaaatatt ttgctacatt ttcctttttt taatgttaaa
     5761 ataaccttat atggaggtgg attatggact cattatcatc tttgacacct gtcgaggtag
     5821 ctgaattatt aaagataaca aaaaatactg tatatgaatt aatcaaaaga ggtgaacttc
     5881 cttcttataa agtagggaaa aaaataagag ttgatactaa agatgttgaa gaatatatca
     5941 acagccaaaa aactggtaaa gtaaaggata cacatttcaa caataaaaat atagatataa
     6001 ataataattt caaaattatt atttctggtc aagatgtaat attagacatt ttagctaggt
     6061 ctgttgaaaa aaaattggat ggaataagta catttcgctc ttatataggt agttataatg
     6121 ctttgtatga gttatataat ggcagagttt ctatagcatc atcccatcta tgggatttcg
     6181 aaacggatga atataatagc acttttgtta aaaagctatt gccaggaata ccatgtgtac
     6241 ttataaatct agcttataga atgcaaggtt tctatgttgc taaaggaaat cctaaagaga
     6301 taacaacctg ggaggattta acaaaaccaa gtataaccat tgtaaatagg gaaaaaggtt
     6361 ctggaactag ggttttacta gatggtaaac ttagacttct aaactttaat ggtaaacata
     6421 taaaaggtta tgataatgaa gaattatcac atcttggagt tgcaagtact gtttctcgtg
     6481 gaatagcaga tgttggtttg ggaaatgaaa aagctgcttt acaagtaaat aatatcgact
     6541 ttattcctct tcacaaagag cgctatgatt tagttattaa aaaagaagac ttacaaaatc
     6601 cagtttacca aactataatt aacataataa actctcctga gtttaaagct gaacttcaag
     6661 gtcttggcgg atatgattta actgatactg gaaaaactat agcaaaagtt taagattaaa
     6721 atcgcaatct attttataag atttataatt tttcacaaaa tttataactt aaacacgaaa
     6781 taaattgcga ttttagtgtc tcaaaaaatt tatgtctttc attttatcat ccaatacaaa
     6841 atttaatata attaattgcg caatcatatt atattaatat atatttacat aatagtattt
     6901 ttctttaatg tagattaaca tatgatatgt tttaaacatc aatacccttg ctttcttata
     6961 tatatgtggc aacacatatg agtttaataa attatataca atgttgcttt cttcttgtat
     7021 tttttcaacc aacaagttat ttataaaatt acctttctca ttttcaataa tctcactcca
     7081 atttatctta acttttaata tatatcttcc cactaggtat acacactcta caataaataa
     7141 taaaaataca atgcagtcag tacctgttgt cttatataaa ttacccgata ctaatggttt
     7201 tgcgaagaaa ttataaaaat tcaaagtatc acccgtataa tcaaaaagta ttaatagcac
     7261 tcctagaact ctcaatactt taatattcaa catgttttta tctttattat ttttgttttt
     7321 catatatact acctctcttt tctttagatt tgattgtaat ctaatactaa ctcttttatt
     7381 tgaggtataa atgaatttaa ttggtagtta ttttcatttt tactagaaat taattcacat
     7441 tactaaacaa aacttatatt taaacataaa aatagcctat ctatttttta ataaatacaa
     7501 aaataaataa gctactaata ttcaattaac ttttatcact taaaacatta ctatctataa
     7561 atttaaatat tttattgaag tatactgtac tatcatgttc aaatccatca acatgaccaa
     7621 taccttctat aagccatagg tcttttttat catgtttaac taaatcatac attttcttgc
     7681 tattttgata attacaaaca gtatcttttg ttccatgtat aaacagtatg ggtacattag
     7741 atttctcaac tgactcatat ggttttacat cactgtacca aaatccagat ttaaacttat
     7801 tatataaatc tccacaagtc accacataat tgattaatat atctggtatt cgtttttcta
     7861 gtactcccat tctaattgca tctttcattt cagaataagg agaatccagt atataaaaat
     7921 cgaccttatc atcttttgaa tttatctctg aatgcatagc agctgtccct gcccccatgg
     7981 aaaatccatg cacacctaat ctcccttcag gaaatttatt ttttacaaat ttaactagac
     8041 tatctaaatc atacctttca taaagaccaa atgtgtaatt atctccacca ctattaccag
     8101 tatttctttg attataaact aatacattat aacctttatc taaatatcta tatgctacct
     8161 ttaacatttc atagtaacta cttccaattc catgaacaag tatcatagta tctcttgtct
     8221 ttatatttga agttataaaa agactttcaa gcttgtaatt attagaactt tgtatcatta
     8281 attcagatgt cttgtagttt tttaatttct ccagcggttt atcttttctc tcagaaaata
     8341 tttttactat atcttcgttt tttattaact gctctaaacc aaccgaacta ttatacacta
     8401 atttgccaaa tatataagat acaattaata ggattaatag aaacacaatt gatataatta
     8461 taaatttatt tcttaaacta atacaatttt taaaactatt tttcatattt atttaccata
     8521 caattttcct atattatatt ttctaagtaa tagcataatt gattatacta
//
LOCUS       DAEPXW010000134         8524 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.138, whole genome shotgun sequence.
ACCESSION   DAEPXW010000134 DAEPXW010000000
VERSION     DAEPXW010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8524
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.138"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(250..1119)
                     /locus_tag="KRM55_003313"
     CDS             complement(250..1119)
                     /locus_tag="KRM55_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1595520.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(1216..2073)
                     /locus_tag="KRM55_003314"
     CDS             complement(1216..2073)
                     /locus_tag="KRM55_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1595521.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            complement(2288..4306)
                     /locus_tag="KRM55_003315"
     CDS             complement(2288..4306)
                     /locus_tag="KRM55_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH1595522.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            complement(4577..5353)
                     /locus_tag="KRM55_003316"
     CDS             complement(4577..5353)
                     /locus_tag="KRM55_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH1595523.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     NTVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(5410..6381)
                     /gene="asrC"
                     /locus_tag="KRM55_003317"
     CDS             complement(5410..6381)
                     /gene="asrC"
                     /locus_tag="KRM55_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBH1595524.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            complement(6394..7185)
                     /gene="asrB"
                     /locus_tag="KRM55_003318"
     CDS             complement(6394..7185)
                     /gene="asrB"
                     /locus_tag="KRM55_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBH1595525.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            complement(7186..8193)
                     /gene="asrA"
                     /locus_tag="KRM55_003319"
     CDS             complement(7186..8193)
                     /gene="asrA"
                     /locus_tag="KRM55_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBH1595526.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
BASE COUNT         2768 a         1522 c          763 g         3471 t
ORIGIN      
        1 aaagttactt aataaaaagt tactttactt tttattattt aaattcctgt ttttattata
       61 ataggtaaaa ttctattaaa ctagttcaca ttttcattat tattgatata ttatatatga
      121 atataccatt ttgtttttta ataaaaaaat catgctacat caatagtaag caactattaa
      181 tgtagcatga ttttttgtat ctaaataatc ttagtattta cctatcaata tagattgata
      241 tatcaaaaac tatagtcttc tatattcttc tctttttagc ttttggttac ttagatagta
      301 atcaatttca tcaattagac gttgtttatc atcaggtaat acacctttta aattagcata
      361 atttgatgca tgattacttc taaatacaat tttttcatta gcatctatat tctttatcat
      421 ctctttaatt tcttgtaaca cagccttatc ctctagtatt gtaaactctc ctgccttaag
      481 taaatcgtaa agttcagtat taggttctac cattaaacta agtacaccca cataatctgg
      541 tgaaattgct cctaacattt ttcctgtatc aactgcatgc tgatgtgttt ttttagttcc
      601 tccaagacct gctattacag tggctgataa tttaatccca ctttttttaa cttttctacc
      661 aacttttatt aattgttcac tactaaaacc tttcttaata tcttctaata cttcattgct
      721 tccactttca agccctagat aaatcatttt aacaccaagt tttcttaatt ctttaagttc
      781 atcatcagat tttttctcta tagatttagg agagccgtac atagtaattc tttcacactc
      841 tggaaaaact tcttttatat ataagataat atctcttaat ttctccattg gtattatcaa
      901 tgcatctcca tctgctaaga atattctttc tacatgctta taatatcttc taaatatatc
      961 aatttcattt tttattactt ctagtggctt tattttaaat tttttagatt tgtacatact
     1021 acaaaacgta catttgttat gagaacatcc tagtgtgact tgtattataa gactataagc
     1081 ctcacttggt ggtctgtaaa gtggcatatc gtattccata ttaaaatccc ccttgtaata
     1141 aaatattcat tctattatat tattaatatt tactttaaat aataacttat aaaattatat
     1201 tttttaaatt ttagtttaag atatattctt taaaaattta atgatactat tggcagtaat
     1261 attaagttgt ttttcttgac ttataatagc atcattatct cccttttgtt ttccataatc
     1321 tccaaattgt gcatgatttc ctccttcaat ctcaacataa gttgtatcat caggaagttt
     1381 ttgttttgat tctacaagac ttttaaaatt gactactcca tctttgctcc cccatataga
     1441 tataactttt tttcctaatt ctttcaactc atcacccatt ggataagaag ctaaaaatac
     1501 aacgccttca attaatttat tatcacgtgc aaaatttgat gctgcaactc ctcctaatga
     1561 atgacctcct attacccaat gttctatgtt gttgtaagaa tccataactt tctgtgcctt
     1621 attagttcca agtatagcta gattaagtgg catctttacg attacaacct catatccact
     1681 ttctgctatt tttcttgcaa gtggagcata agattctatt tctactttag ctcctggata
     1741 caaaattaaa cctttagaaa cttttcttcc ttttggtgta aatgaaatgt tttcatttac
     1801 agttacttca actttactat tgctgactag agcttctttt gccagctttt gaggttcata
     1861 tgttttattt atccatatga aaaagccaag caaaatcaat acaaatagta tacctattcc
     1921 cttaaatatc ttattcttta tgttaaattt tctattatta tttttatcat ctttgttctc
     1981 aacctcatca taaagtaaag gtctctcaag ttccatagtt atactaaatg tatcatattt
     2041 cttattacgc tttaccttta catctttact cataaatcta acccccataa tatttgaata
     2101 ctattatagt ttatcctaag taaattgttt tttcaaccaa tgaaaaaaat caatatttta
     2161 actattttca tataaaattc ataaatatat gttttttgtt ttttatatat tattttcttt
     2221 tagtatttta taaaacaaat agccatatac tttattttaa atatatggct attctataat
     2281 ttaatatcta agctgcttct tttattgaaa ctttagttat attacttatt ctatacattt
     2341 ctttgacacc atttagagtt tgcagtaagt ttagacatat tatcttgtca cctagacttt
     2401 tagtatttac aatactctct aaaattacac ttcttccttc atcatactta tctacattgt
     2461 aatttgaaat ataattagta tctctcaata ttttttcaac atcttcatct tttattttat
     2521 ttttattaac atttatatat agattataca tattacttat tagtaatttc tgattttcta
     2581 aaaaatcctc ttgatgttta tctttatata tagcatttat caacataagt ctatcttcaa
     2641 taagtgatgg tatcaataat aaatttttta tatagtaaac atcagctaca ttttctatag
     2701 acttattgac ttcatcaatt atatttttaa ctattccttt atacatttct ataacatgtt
     2761 gatagcctgt tttagcatca tatggtaata taaacttatt tactattaat gcaataattg
     2821 ctcctaatgc tacatatgaa atcctgctta ttgttaaaac atttgggtct cccataacta
     2881 ctgctgaacc aagagctgaa acagttacac ataccattaa ttttctataa tcaactacat
     2941 aagagtttat ataccctgct aaaagaacta ttaacgacct taatgtacta tcttttatta
     3001 ttgaaaataa tacaataaat attacagctc ctataaatgt accttctatt ctttttctag
     3061 acctttgtat acaattttct gcgtaaggtt gtgttaatga aaagacagtt aacattatcc
     3121 atcttccatc tcttaaatgg aaataatcca taataaaacc cgctacagct gtagctaaag
     3181 caatctttac tgcataagaa aatcttatag aatttaaatt aaagtttttc ttatatattg
     3241 atagtcgttt aaattcatga ggtatctttg attttctttc agctttcttt tcgtctcttg
     3301 attttacttt tttataatct actaaaaact catataaatt ttctaaaaca ctataaattt
     3361 cttttaaatt tatattttta gtatcctgag caataacata atctctaaat cctaatatct
     3421 ctttatcagt tatggtatct ttattttcta aacacatctt aatatagttt atttctttcg
     3481 ttgctacaac taaaacatct gatttactat ttatgctact ttcttctaaa atatttttta
     3541 tatcttcatc ttcaaattct ttactatcct ttttgtatct ttccaggatt aaacttattc
     3601 tttctaatga aaataaaata ttcattatgt ctatacctct aatactgata taaaagtcat
     3661 cttttctatt atcaaaaata accattttca aatttttaga tatagaattt attctataat
     3721 tacagctatc tatttttctc atactagatt taattataga actatcatca ttaatagtat
     3781 tttttaaaag actaattttt tctaataatt catcacatat agatatcagt tctttatctc
     3841 cgacattttt catcctattt ctattcataa caaattgagc aatcattatt ataactgctc
     3901 caacagctaa agccgacaat ctcataggaa attcactttt tcctacaggt atacttacca
     3961 taaatatata cattagacca aagggtacat atactgctct ttttaagtca taactaaata
     4021 cataccctat tataaataat gctataaaat ttaataaaac tcctaaatac atattttgta
     4081 ctgcaaaaaa tgatagtatt cctaagatta tatttattgc taaatacttc agtaaatttt
     4141 taattggaga aatagttaaa tctctttcca agagtgttag catagctgtt actataccta
     4201 cacctataag tgtattttta cttccaaata aatatataaa tatagaaata aatgctatta
     4261 taaaaataaa caactttgtt tttgatatta ctagtttctt tgtcatcata tcccccctaa
     4321 aaatttcaac aagaccaatt ttatcatatt tgttatctta ttcaaaatgc gcttttttac
     4381 ggtaggactt taactttttt tatatttaga actatataat tcatatataa acgtattttt
     4441 tatatatata actgatatat tttcgtatgc tcccatattt tttttgtttc aaatattttt
     4501 tcaaaaatat aaaaataact ctctcaacaa tactaaaaat atatttatca agagagttat
     4561 aatttataca ataaatttaa ttaagctttt ctttacctaa tatataagtt ccaagaccca
     4621 taaataaagc tcctccaaca atatttccaa gtgttacagc tactaaatta taaatagctc
     4681 ctccaatagt aactgtattt attgttggtg aaaataatga aacactataa attgtcatat
     4741 ttgctacact atgctcaaag cctgatgtta taaaagcaaa taaacataag aatatcataa
     4801 ttatttttgc agtatcacta ttagttctaa acgaacacaa cactgataca catactagaa
     4861 tattacataa aatccctcta aagaaaagag ctgtaaatgg catggatgct ttactagctg
     4921 ctgtatttgc aaaaaattca gctacaggtc ctttgtctac tagaccagtt cctacaaata
     4981 taatgcctaa aaccaaagct ccgattaaat tacctaccca actgtatgcc catattttag
     5041 aagtatcttt tatacttaca cctttattta acataccagc agacataacc atattgtttc
     5101 cagtaaataa ctctgttccc gtcattataa ccaaacttag tgctattgca aatgataacc
     5161 ccattactat cttagtcata ggtgaacctg catcagtcaa aagtcctcca atagtaaata
     5221 tcaaaagtat acctatacct acataaagtc ctgcaaacgc agaagatacc aaatatttta
     5281 ctttacttgt gtttaataaa tttatcttat ttatagctgc attagttaat ttatccaaag
     5341 tttctttatg cataattccc tcttccttct attaaatttt aatttattca aatatatgtt
     5401 ttactcaatt tatagatatt taattccact ccagtatatg ttttcgtaca ttttagttat
     5461 ttctggaagc tctacacctt caagtgccca ttttttaaat tccataaatc ctgttctatc
     5521 aattatatat cctatatgtt cttttcctcc tggtgcatct ttatctatat acttttctac
     5581 atatctataa gtattaagta ttatctttat tatgctgtcc tcatctaccc ataaaagaaa
     5641 atcttctgct agtctagggt ttttctttcc tgttctaccc attatagcta atctatagta
     5701 ttttttctca tctctagtcc atgcatttgt tgggcaattt agtacacact ctccacagcc
     5761 tatacactta tctttatctc ttaccacctt attattttct gtttttaatg ctccaacaga
     5821 tatcttagaa cattttttta cacatgctcc acaatttaca catctatcct tttcatatat
     5881 tggtaaagcc ataccaataa ttccaaagtc attcattcta gcttttatac aatcatttgg
     5941 acaaccagtt aaagccactt taaaatgtaa atcatttgga aatatagctt tttctattct
     6001 tttagcaaat tcagttgtat tatattgagc ctttggacag actttatttc ctatacaagc
     6061 tgctatattt cttgtacctg ctgctggata acctgcgttt ttctcacttt gatttatatt
     6121 cattttttca ataacaggtt gtataatttt atttatttct tccatatctt ccatatttat
     6181 tcctaatatt tcaaacccct gtcttgtagt tatgtgcacc tgtccattgc cgtactcact
     6241 tgcaatttta gaaactacag ctaaactctc agggtcaata agacctccag gtactctaac
     6301 tcttaaagaa gtctcatatt ttgtttttgt aattctataa gcatttttca ttactttttt
     6361 ggtatttaaa tctcttatca caaacttcac cccctaatca ataagatttt tagcatatga
     6421 ataatcaaat actggtccat ctaaacatat gtaagtatca tccattttac aatgtccaca
     6481 tttacctatt ccacaacaca tttttctttc ataagaaacc caaatgttct tttcatctaa
     6541 atctcttttt aaaaattctt ctactgtaaa tttcatcatc attggaggtc caactacaac
     6601 tatagaagta ttgtttatat ctttcatatc caattctggt atgtattttg ttactaatcc
     6661 tacattacca ctatatcctt cctctgctcc atctacagta actaaaatat caagtttttt
     6721 actccatctc tttaaatcat ctgcaaataa aatatctttt ggtgatttaa atcctactat
     6781 taatttaaac ttttcgcatt tttctttatt attataaaaa tattcaacta ttcctcttac
     6841 aggggctaat gcacttcctc ctgccactac tacaatttct cttccttcat aaagggatac
     6901 atcaaatcca tttccataag gacctcttat aaaaaaagaa tctccttctt tataattaaa
     6961 caactcgcta gttacttttc ctacatttct tattgtaaag tcaatataat cctctccata
     7021 tcctgatact gatattggac tttcaccgta tttaggtata gatatctcat aaaactttcc
     7081 aggcaataca ccttttgtat tgcagtttac tctaaaagtc cattctttat cagtatgttt
     7141 aactatatct agtatttttg cacttactgg tatatatggg ttcatttata cttcctcctt
     7201 actaattact aaatcattta ttttttctat acactttgaa aatgatatgt attgcggaca
     7261 ggcatcatca catcttccac aaccaacaca catatgatat ccgaatcttt ttttaaaatc
     7321 atgtatttta tgcatagttt taaatctcat tctttcacct tgtttttttc taaaagaatt
     7381 tccacctgct atatctgtat atccatctac ttgacaagaa gcccaaaccc ttcttctctc
     7441 acctacattt tcgttttcct tatagaaaat atcctgcatt gtaaaacatg aacatgttgg
     7501 acatacaaaa ttacatctac cacatcctat acatcttgta tcatattcat cccatattga
     7561 atttcctatc atttcatttg aatcaatatt ctctggcaca tctacagata ttaaattatc
     7621 agttacataa tcaacattaa attcagttgc ttctccatta aatacttcaa attcactatc
     7681 ctttatatct aagtacagtg tatctccttc tatatttaat ccaattgaat aattatcagt
     7741 tttgttagaa tccatgctca cacaaaaaca gtttctaaaa ctttccttac accctacaag
     7801 tgcaaacttt actttatctc tgatattttt ataaaaataa tctttttctt caccattatt
     7861 tagatatatt tcatcaagtc tttttatacc atttatgtca caagctctta agaaaattaa
     7921 aattttcttg ttgtctaaat cgctttcctt aaactctttt tcagtaaaat aaaacaatac
     7981 ttgatttatg ggaagtacaa cttcttttgg tgaaaagttt gctttcttag caaattccat
     8041 ttcttcaaaa gcgtttacct ccttgtatct tataacatca gtatctgaaa aagtaccttt
     8101 aaatgggatt aaaactggtg caaatatctt gtagtctttt tttagataat tcagaccttc
     8161 attgaactta gatgaatcta attttagttt catttttatc acctttctta tattttagtt
     8221 ttacttactt gctatcttgt ttaaatctta acactttatt ttctatgctt ccgtgataat
     8281 tatcacagtt tcaaaaataa taaaaaaaat attaatggag tttattaagt tctgttaata
     8341 tttttttatt atctacatta ttcaatttca aatctaatca cttaaataca atcattaagt
     8401 acaataaaac tactatctac tcaatttttt gaataaaaaa gaatcttatt tgttttttta
     8461 tacaattcaa tagggtaaaa taaaaattaa taaattagac aataaaaaag aatctataaa
     8521 taga
//
LOCUS       DAEPXW010000135         8373 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.139, whole genome shotgun sequence.
ACCESSION   DAEPXW010000135 DAEPXW010000000
VERSION     DAEPXW010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.139"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            158..1051
                     /locus_tag="KRM55_003320"
     CDS             158..1051
                     /locus_tag="KRM55_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1595527.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            1229..2053
                     /locus_tag="KRM55_003321"
     CDS             1229..2053
                     /locus_tag="KRM55_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1595528.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            2152..2760
                     /locus_tag="KRM55_003322"
     CDS             2152..2760
                     /locus_tag="KRM55_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595529.1"
                     /translation="MEKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            2864..3040
                     /locus_tag="KRM55_003323"
     CDS             2864..3040
                     /locus_tag="KRM55_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595530.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            4306..5058
                     /locus_tag="KRM55_003324"
     CDS             4306..5058
                     /locus_tag="KRM55_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595531.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            5048..7159
                     /locus_tag="KRM55_003325"
     CDS             5048..7159
                     /locus_tag="KRM55_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595532.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            7543..8253
                     /locus_tag="KRM55_003326"
     CDS             7543..8253
                     /locus_tag="KRM55_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595533.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
BASE COUNT         3165 a         1067 c         1112 g         3029 t
ORIGIN      
        1 aattatattt agtgtaaaaa taattaatca aaatataaaa aataggatat tattataggc
       61 aataactaac atcaagcgat aacttaatac atataaaaat aaataaacaa ttaataaaaa
      121 ttaaaacttc attataaaac ggaaggatag tgaaaaaatg caactatata acaccccctt
      181 taatacaaac aaacacttaa tctatttctt tacatttacg ctagtattga actggatatt
      241 cagtcttaca cctgcgttgc tcggaattac aaatacaata cttggagaaa tcatttttta
      301 tcttgcatat acatcaccag ctattgtagg tctatttttt atttctacaa tctatccaca
      361 aagtgcaaaa caagatttta tttatagata cctaagcttt aaagaaatcg gaataaaatg
      421 gatactatta acaatattat tttttgcttt aacttttatt acttcgttaa taatcggaaa
      481 ttactttaat gtaaaaactt ctgatataga ttggatacac atagcagtgt ttagaccttc
      541 taaaatagct tatatgctat tagcaagttt tatattgagt atacttagtc aagaagctgg
      601 atggagagga tatgccattg acaaattatt agttagattt ggatttatag gctcttcaat
      661 tattttaggg cttgtttgtg gaatctggta tctagggtcg tattttacac ctaatcaaat
      721 accatataat ttggcacaat actccctatt tgatgctttt ttatttatac caaacattgt
      781 acttttaaac tttataatta attttgtata tatcaataca agtagaagca ttttatcagc
      841 tggattagtt catatgatgt actatttttt caacattcaa ttacttctac actaccctat
      901 taaattatgt gtaatagctc aatatgtaca aataatattt ggtttaatat ttcttgtata
      961 tatgatttct tctaataaat ttaaacagaa ggtaaattct gaaattgaac agataaagtc
     1021 ggatgatttt gaatttgagt tagactggta attttaatat gaattataaa ttaagataat
     1081 ctatgatttg atacgattac tacttaaata taatttactc tctataattt attgcaacat
     1141 ctggaaaata attgtatttc cacaaacgct tgaagtatat aaaaacaaaa tatatactga
     1201 ttataagtga aaaggaggtc atattttcat gtttaaaata ggagaggttt caaaactaac
     1261 acaaatttct attcgtatgt tgcgttatta tgatgaactt ggtattttaa aacctgcaga
     1321 aatagacaaa tatacaggtc atagattata ctcagttgaa cagatttcaa tattacaaag
     1381 aattgtatta ttgagagatt caaaatttag cgttgcagaa atagcaaata tcgtacataa
     1441 ttggaatgat gaatttgtaa ttaaggaatt gaatagaaaa aagaatgaaa tacaaaagga
     1501 aataaagcag gaacaacaaa gaataaataa aattgataaa tttatagaag ctataaactg
     1561 tgataaagat gaaattcatt acaatgttgt ctttaaaaag attccaagtt ataaaatcat
     1621 atcacttaga gagataattc cagactacca atctgaaggt atactctggg aaaagctatc
     1681 taaatttatc aaagaagaac atatagaagt atcacgtcaa tccaacaata acatagcttt
     1741 ttaccatgat gaagaagtca aagataatgg tgtagatatt gaagttggaa tggttgtaaa
     1801 gaagattgga aagaacaaat ctggatttat atatcgtgag acagaagaaa ttgatatgat
     1861 ggcatgtact atggtttatg gtccatatga aaatatagct ggtgcatatg aatcgttctg
     1921 ttattggtta gataaaaata gtgattatca aatatcaggt ataaatagac aaatcggtca
     1981 taaaggtgaa cataatgaaa taaatcctga aaattatctt acagaaattc aaatccccct
     2041 tataaaagtc taatcgatta gtacttaaat acttaagtac taatcaccca ttgacatccc
     2101 aaaattttca tgatagtatc taaacgtgta ttaaacatgt ttaatttttt tatggagaaa
     2161 cttttaaggg gaaaaattat gaaagcagat tcaacaaagg aacaattaat taatgccaca
     2221 atccagttac tatcttcaca tagagatgtt tcaagcatta cggctagaga aattgtagct
     2281 aaagcaaatg tcaatttagc tatgattaat tattatttta aatctaaaga ggagttaatt
     2341 aatatttcta ttaaaaaatt tttaaagcgt catatggatg aatataaggc tacacatgat
     2401 actaaaaatt tagcacctaa acagcaatta agggaaatac taattgcatt ttttgatttt
     2461 ataggtgaac atagtcaatt tataaagatt tctgtaccct atatattgat acaggaagaa
     2521 attgtttatc catttgagat actaccttta attaaggctc actatgaaaa tcagaataac
     2581 aaaaaaactg aagctgaata cagaactatt gcgtatcaaa taacttcatt tattcagttg
     2641 ctttttcttc gttctaatgc ttttttcaag tatagtggta ttgatattct taatattgaa
     2701 cagagaaatg gtttaataga ttttcaatta gatttattat tggtagatat tacaaaataa
     2761 tactatatta attttttatg tacatttttt tattttatgg taacgtttga aaatattctc
     2821 attgactaaa aatacttgca ttaaataagg gggaggaatt ttaatgtttt ttacatttat
     2881 aggagtaata tcagcaattt tattgttgtg tacaattata tgtggtttat ggataaaact
     2941 taataatcgt aataatgact ctaattctca ctttactttt tcaatacttt caattgcttt
     3001 ttcactgtta attgtggtgg cctttttagt aagaaattaa tgtctttgtt atgctgaggt
     3061 ttattattat agatttttat tattgcatga tttttactat attatagtat ttttattata
     3121 ttacagggtc ttatttatta tagtgttttg ttgttacagc attttattat attacagagt
     3181 cctatttatt ataggatttt tattatattg taaaatctta tttattatag gattttgtta
     3241 tattacagac ttttattata ttgaaatctc ttatttattg cagtgtttct attatattgc
     3301 aaactcttat ttattatggt gttttgttat tgcaacattt ctattatatt gtaaagtctt
     3361 atttattaca gttctttatt atactacaga cctttattat tacagcattt ctattacatt
     3421 gtaaagtctt atttattaca gttctttatt acactacaga cttttattat tacaatctct
     3481 tatttattac agttctttgc tatactacag acctttatta ttacagcatt tctattacat
     3541 tgcaaagtct tatttattac agttctttat tatactacag acttttatta ttacagcatt
     3601 tctattacat tgcaaagtct tatttattac agttctttat tatactacaa acctttatta
     3661 ttacaacatt ttattatttt aacttcttta ctataatata gtaatatttt aatatctcaa
     3721 aatcatatca atcacttttc agcatagtct aaaatacttc cactttctaa aattatctat
     3781 catacctata ctaataatac tttttaacct ttttattata catttcaatt gtttctaaca
     3841 acctatttat ttccaaaact ccaatatatt ttctcaatta cattgtgtta atagccccta
     3901 aatcctttca aattatttac aatacattct attaaataat cttactgctc tataattctt
     3961 tttttctttt taaccctact atacattatt tacatcattt ttttcaatac aacattcgtt
     4021 attctataac ctttttactt ttactatata cttcttttct aactacacct tcaatgttcc
     4081 acatcatatt actttagcac aacaattaat acctaaaaat aaccctctaa atcctccaat
     4141 aatataatca atttaactat aataataacc tctcacacta tccaaacaat atattttcaa
     4201 acattacaaa aaaacatcca actattacaa tatagctcat atccctcctc ccctttcaaa
     4261 tgctatcatt gacttacaag ataaatgaaa gtgaggatga tatatatgct taaagtaaac
     4321 caattatgta aatcatataa aacaggcagt aaaacatatc ctgtattaaa aaatatttct
     4381 tttgaaatca acaaaggaga atttgtcgca atcatgggtt catcaggaag tggaaaaact
     4441 actcttttaa attgtatttc atgttttatc ccaattgata atggggaaat aattcttgga
     4501 aataataata taagaaattt aaaagaaaag gaactttcag aagttagaaa tcaacaacta
     4561 ggatttgtat tccaagactt catgctattt gatggtctta gtgtctttga aaatatatgt
     4621 gttccacaaa ttatcaaagg tagtcaagtc ttacaaatgg aaaaccgtgc aattaatcta
     4681 tgtgagctat ttggtattga acatatcaga aaaaaatacc ctgccgaaat atctggtgga
     4741 gaaaaacagc gtacagcagt agcaagagca ctcatgaaca acccagattt aatattagca
     4801 gatgaaccaa ctggtaacct tgatagtaag tcttgtcgta cagtcattga atcattttta
     4861 aaagcaaagc aagaattaga tgctactata ctcatggtta cacacgatag ctttgcagca
     4921 agcttctgtg accgagttat tgtgcttaaa gatggaataa tttataaaga agttgtaaaa
     4981 tcaaattcaa gacataaatt cctagatgaa ttactagaag ttttaaaaga aatgggaggc
     5041 gctcaagatg acaattaata aattatacag taaacttcga gcctataatt ggaagaacta
     5101 tacaacttta ttcttttgta taatactttc tgtggtatta gtaacttcat atgctctaat
     5161 ttattttagc ccaacaatac aaaacatact tccaactggt ggagatagca gaaaacaggc
     5221 tacaatgata ttctcagttg ctatattagg atgcgctgtc tttactacat acgcttcttc
     5281 cctcttttta aaatttaaaa gcaaggaaat tggtattttc atggctctag gaacagataa
     5341 gaagaaatta aaaaaacttc tattttcaga gatattgtta atttcaatag tatgctgttt
     5401 tttaggtctt atattaagta ttcctgtatc ttttggtata tggaaaatat ttcaattagt
     5461 gattattgat accagagaaa tgacatatca ttttggaact caaggattca tatatggatt
     5521 tatatttagt gtatttgtga cattatgcat atttatactt tctgtaaaat ttattaatcg
     5581 tacaaatata attgatatat taaatgacca gagaatatct gaaccaatac aggatgtaaa
     5641 ggactggtat ggtatattag gtataatttt tattatactc ggtatttttc taggatatct
     5701 cgtaccttca ctaactataa acaaattaaa ttataaacta ccatctatat ggagctttac
     5761 ttatctactc tctcttattg gaatatatat gattatgaca tacatagttg tacatgctaa
     5821 aagaggaaaa catccagaga aatactataa aaacatcata tcaactagca tgatgagatt
     5881 tatgggaaga caaacagtaa aaaacatgtg tgttatttca tttttgattg caggagcatt
     5941 atttgctgta ttctatgttc ctaatatggt tacaggtatc tatgatactc ttaaaaataa
     6001 ccctatagat tatactttta cctacaatca aagagataaa caggtatcaa aaaaagatat
     6061 tgaacaatta gcagataaac acaatataaa aattcaaaac tatatggaaa ttccttctat
     6121 agaattaatt gttgatggtg tagaatcaat atatcataaa gatggaacta tcgaaaaggt
     6181 atatatgaaa aaaagctcct atgatatgtt ctttaattct aaagattttt ccaagctaat
     6241 tggcaaacca ataactataa aaaatggtga atatcttgct gttgtaaata aaggaaatga
     6301 aaatcaagat tataaatata ccaaatttat atcaagccca gtcacagaaa aagaaatccc
     6361 ctttagatat gctggaaaaa taatatttaa tggttctttt tttcaaaata gaagtatgaa
     6421 cgcctatgtc cttaatgatg aggattataa atcatttact aaagatttat ccataaaaaa
     6481 ttacaataat tctatactat ttaatgtaga taaagatacc tatgcttttg ccaatgactt
     6541 aaagaaagaa attataaaaa gaacatctaa ggaaatgggc atgttcagtg gttatgatga
     6601 atacgtaaaa aaacgttatg aatcaactgg aagaaaatat tttatggatg aagaatatcc
     6661 aagtggtgaa ggtcatttaa aactagaccc aaacaacaat cagttgtatc ttaattggaa
     6721 atactatcct aactttaaaa ttttacaaag ccaagatatg ataaaaaaca tggcagtctt
     6781 cttaatgtta ttcatatatg tggcaatcat atgttttaca gcagtaggaa tcattgcata
     6841 tacaaggggt gttactatag ctataaatca caagcaggtc tttatggatt taaatcgatt
     6901 aggagcaaac aatgattata taaagttctg tattagaaat caattaaaga aagtattttc
     6961 ataccctctt attgcaggaa gttttttaat ttatctgttt aattttatga ttatgttaaa
     7021 taatgatggt agaatcgtca atagtgaggt caatgctctt ttgataaact taggttttat
     7081 agggatttgt ggggtttata tgtaccttat atatctatta acttataaga aattcaaaaa
     7141 aattattggt attttataat aaaaaaggtt attagatttt taaagtaata aaatcattgg
     7201 tgttttataa taaaaaaggt tattagattt ttaaagtaat aaaatcattg gtgttttata
     7261 ataagaaagg ttattagatt tttaaagtaa taaaatcatt actttttata ataataaaag
     7321 catttgtatt ttataataag aaagattgtt agatttttta ataagaaaat cattagcact
     7381 tcagaataag tttaatagaa tagttttaag tgtaagtata ctaatataaa aaattttatt
     7441 ttgctatctg gatataattg ttatttcatt ttatatatct aggtagcaaa atatattata
     7501 tacttaacta tataaatata aaatttgaaa ggagataaaa aattgacttc gatttgtatt
     7561 tgtgatgatg aaaaacaaca aagaaacatg ctgaataaaa tcattacaag agaaatggat
     7621 ttgtggggct acccctacca aataaaagaa tattcaaatg gagaaagtct agtatacaat
     7681 ctagaacacg aaaattatta catagatatt atttttttag atattgaact tggaaaaagt
     7741 aatggcgttg acatagcaaa aactatacga aaacattcaa aggatactat aatcatcttt
     7801 gtcacaggtt tttctgacta tgtatttcat ggatatgatg taggagcttt gaactacatc
     7861 ttaaaacctt ataaaactga aaaaatatgt aaagtattaa aagaagcact aaaaaaatta
     7921 gaacaatgga aagaaaactt tattacagtt cagattggaa ctaatctttg taaaattaat
     7981 acaaaagata tcctctactt taaaagtgag ctaagaaaat taactgtagt tacctttgat
     8041 aaaacattag aatactacgg aaaattaaat gatatggaaa ctgttcttcc ctctaatttt
     8101 atacgtacgc atcaaaggta tattgtcaat ctaaaccatg tagatagtat aactcaaact
     8161 tatgccaaag ttcagaatga aaaaattcct ataagccgta aaaaatatca agaggttgta
     8221 ggaaaattta caaggtatat gttagaatct taatttttga agttcaatct ctagaatttt
     8281 atttttgaaa cttaattttt taaagcttag tttttagagt tttgtttttt caaatttaat
     8341 tttttgaaga ttaatttcta gaatttcaat ctt
//
LOCUS       DAEPXW010000136         8372 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.140, whole genome shotgun sequence.
ACCESSION   DAEPXW010000136 DAEPXW010000000
VERSION     DAEPXW010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8372
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.140"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            268..1731
                     /locus_tag="KRM55_003327"
     CDS             268..1731
                     /locus_tag="KRM55_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH1595534.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            1787..2923
                     /locus_tag="KRM55_003328"
     CDS             1787..2923
                     /locus_tag="KRM55_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1595535.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            3159..4274
                     /locus_tag="KRM55_003329"
     CDS             3159..4274
                     /locus_tag="KRM55_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBH1595536.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTIMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLDPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            4426..5295
                     /locus_tag="KRM55_003330"
     CDS             4426..5295
                     /locus_tag="KRM55_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1595537.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSRRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            5487..6377
                     /locus_tag="KRM55_003331"
     CDS             5487..6377
                     /locus_tag="KRM55_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1595538.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            6595..8349
                     /locus_tag="KRM55_003332"
     CDS             6595..8349
                     /locus_tag="KRM55_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBH1595539.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNDVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDITPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
BASE COUNT         3321 a          820 c         1524 g         2707 t
ORIGIN      
        1 tttcaggctt ttcattatat gtattccaat ttatattgtt tgattattat tcaaacacac
       61 gtcgttaaaa attttataaa tttatgttta gatatgatta atactcttga ttttagaaat
      121 aaatatttgt agattgtaga ttaaagataa tataaataaa tagaaggtag attttttaga
      181 tatattaata taaagattat ataaaatatt gaaatatagc tgtttaaatt attgtctata
      241 aatataaaat gaatggtggt gagttaagtg accgatttag ttaacaccat taatggaatt
      301 gtttggtcac ccgtattagt tgcaatgtgt ttgtgtatag gattatattt ttcattgaaa
      361 ttaaaatttt ttcaaataag agatgtaaaa gaaatgttta ctctcttgct tgaaggagat
      421 agttctcatg ttggtatatc atcatttcaa ggttttgcta catctatggc tggaagaata
      481 gggactggaa atatagctgg tgtagctgta gcaatagcaa tgggaggtcc aggagcatta
      541 gtatggatgt gtataatggc tacattaggt tcagcaactg catttgtaga atctacttta
      601 gctcaaatat ataaagatga gcatgatggg cagtatagag gaggacctcc atattatttt
      661 gaaaaaggtc ttgggtggaa aaagtgttca gttttatttt caatagttgc aataataagt
      721 tatacatttt ttatgcctgg tacacaatca aacactttat atctagcaat gaatcaagca
      781 tttggatttt caaaaatgac aatagcagta gcatcttcta ttgcattagc gataataatt
      841 tttggaggaa ttaaaaggat tggtttattt gctgaaaaag tagtacctat aatgggtgga
      901 gcatacctta ttatgacatt agtaataatt ataacaaata ttagtttagt tccagaggct
      961 attgtaacaa tgtttaaatc tgcatttgga tttggttcag tttttggagg aatgctaggt
     1021 tcagcaatat cttggggagt aaaaagaggt atatactcaa atgaagcagg agaaggttct
     1081 gggacttatg gtgcggcagc agcagaagta agtcatccag ccaaacaagg attagttcaa
     1141 gcattttctg tttatgtaga cacattatta atatgtatgg ctacaggtat tatgattgta
     1201 ataacaggaa tgtataatgt tacaggtgtt tgcacagcac taccaggtgt agaaccggga
     1261 ccacaatatg tacagagtgc aataaataca ttacatccac aattaggtga tatttttata
     1321 gcaatagttt tattattatt tacatttaca actttattag ccttctcata tatgatggag
     1381 actaatgtat cttacttagt aactagaatt aaagcagaaa aacatgaaaa gtacataatt
     1441 aatgtctgta gatttatgct tatagcatgt gcagcaatgt gttgttttat agaaccactt
     1501 acaagctggg cattaggtga tatatgtata ggtgtattaa catatataaa tttaattgcc
     1561 atctttacac taaaaaaacc agctataaag gcatattatg attatataag acagaagaag
     1621 atgggaataa aaaggagtga tagaactttt aaccctatag agttagatat aagaaatgct
     1681 gagttttggg aaaatagata cttaaaagag gataagcatg agttaaatta aagttataat
     1741 aaaatataaa aattactaaa taaatttagt gggaggtaag attggtatga aagaaagaat
     1801 aatacaagtg gctgattcaa agaaagaaaa aattctaggg ctatgtcaat ctttatatga
     1861 tgaaccagaa attgctttgc aagaatataa atctgctaaa aaaatatcag aatttctaag
     1921 agaagagggt tttgatgttg aggaaaactt ggcaggtatg gctacagctt ttaaagcaac
     1981 caagaaaaat ggagatggtc ctaaaatagc atttatagca gaatatgatg ctcttccagg
     2041 caatggacat gcatgtggac atcatttaat tgcatctatg ggagttggag ctggaatagc
     2101 tctttcaagt atactggata cttacaaggg agaagtaagt ataattggaa cacctgctga
     2161 agaaactgga gatggaaagc cttacttgat agaacatggt gtatttgatg gctatgatgc
     2221 agcaatgatg atacatccaa attcaaaaac ttgtgtaaca cctgaaatta tagcaatagg
     2281 aggtctagat ttcatattta ctggaaaagc atctcatgca ggagctaagc catataacgg
     2341 aataaatgct ttagatgcag tagtactact atataataat ataaatgcac taagacaaca
     2401 attagtagat ggaacgagaa tacatggtat tatattagaa gcaggaactg ctgcaaatgt
     2461 aatacctgat atgggaaaag taagattaga gataagggca aaagaacaaa attactttga
     2521 tgaagtagta gaaaaagtga aaaattgtgc tagaggtgct gcaatagcca ctggatgtga
     2581 acttgaattt tatcactttg aaccaacttg ccaaggatta aatgaaaata aagttttggt
     2641 agacatattt acaaagatta tggaggaatt tggaatatat gaagatgaac aagtaatgtt
     2701 aggttcaaca gatatgggaa atttaagtca aataatgcca tgtatacatc ctttgatgaa
     2761 gttttctgaa aatggagaag aactacatac aaaagaattt ttggaggctt ctataaattc
     2821 atatgcaaaa gatagagtaa ttgatggtat aaaaatatta gctttaacag gatttaattt
     2881 atttgaaaat ccagaattat tgaaaaaaat gaaggaagag tagaacttag actattttta
     2941 attatactct ttaaaataag aagagtgtct caaaatgaac tttttagttt atgagacact
     3001 cttttttgta tgaaattaaa tatattttta ttattttaaa catgaaaaag aggcttatct
     3061 gtttttatat gacctttttt aacttgtagc acaaaatatc atgaatgatt acaattcgaa
     3121 tgataaaatc gattataaga tatataggag gggtacatat ggaaacttta gaagtaagaa
     3181 atattgaatt gagtggtaca aattatgaga taggatacag actaggagaa ttggttgcta
     3241 atatgccaga gataatagaa ggtcagatta ataaatctaa tctggtaagc aaaaaagaag
     3301 aaaaagagat gatagagttg tttgataaat attgtccagg tcttaatgaa gaattgcaag
     3361 gttttgctga tgcaattcaa gtgaattgta atcaaatttt atattatact atgacttatc
     3421 ttaaaccagg ttgtagtcaa gttgcattag caccagaatt aactgaaaat gggcatgtac
     3481 tatttgcacg taatttcgat ttctcacaca atatggagga ttttgtttta tgtaaaacta
     3541 aggtaaatgg aaaatatgca catataggta ctaccattat gcaatttgga agaggtgaag
     3601 gtatgaatga atgtggctta ggtgtaagtc agtcatcatg tggtattcct gtaggcaatt
     3661 cagatggttt aagaaaacca gcaattgtag gtttacagtt ttgggctgtt attagatatt
     3721 tgttagaaaa ttgcaaagat gtagatgaag cattagaata tttaaaagat atgccaattg
     3781 catacaatat taatttattg cttgcagata agtctggaaa cattgcactt gtggagactt
     3841 tagatgggaa aaaagaagta aatataatca acagtttaga aagtaaaaga gaatattttt
     3901 tacactctac taatcataca catattgata aacttcataa attagatcca caatcaatga
     3961 aaaattctat tcatagatat aaattaatta aagaatatat aaataagtct aaaaaaattg
     4021 gagagaaaga gttaatgaat ttattgtctt caaaatatcc aaatggctta tcttgtaatt
     4081 actataatga tttttttgga actttaaaaa gtatagttat ggatttaaat ataggaaagt
     4141 ttaatatttt atggggtgga ctagagaata aatgggagag ctactattta aaaaatgaca
     4201 ttaaatctat aacacagagg ataaacataa atattgaaaa agcaccatct gacttttttg
     4261 atttcattga ataaaaaatg tatttaatta ttctaaataa ttaggacata taaatcaact
     4321 aaaagttttt atttatcgta ttgaattagt tataatattt tagtatagta aaaaatagtg
     4381 ctattttaca tatttaaaga gtttaagtag aagagaggtg ccatattgga ttacttaaag
     4441 tattttgaaa aagctgtaat gtatattgag aataatttac atgaaaatat aactgtaaat
     4501 gatgtggcaa aagaaactgg atattcttat tatcatttaa cacgcttatt taagtctatg
     4561 tttggtgaaa gtgtaggaag ttatataaaa aaaagacgat tagtaagtag tacaaaagaa
     4621 cttttatata gtgataaaaa agtgatagat atagctattg gtagtggatt tgaatcttca
     4681 gaagcattta gcagagcatt taaatctata tacaaggtta gccctataga atatagaaaa
     4741 aatagaattg atgtatttgt tggtaaaaag aaaaaattag agttagattt tatgagacat
     4801 cttgttggaa atataacgat taaaccagtt ataaaagaaa tagaaaaaat aaaggtaata
     4861 ggtataaagg ataaagtaat tttagaaaat aattcattac ctgacttgtg ggagaaattc
     4921 agaaaagtac atcatattgt cccaaatact ttgccatcaa ggagagtttt tggaatctgt
     4981 gaagcaatct ctgaaataca cctagttagt gaaagtatgg agtttaatga gataatagga
     5041 cttgaagtta atagttatga tgtgattcca aattcatttg tttcaaaaac tattaaggaa
     5101 ggaaagtatg ctatatttac tcatactggt agcttagata atttagacaa aacttatgaa
     5161 tatatatggg gtacttggtt tttaagttca aaagaagaac ttgatataag agatgatttt
     5221 gaagtatatg atgaacgatt tttaggtcct agtaatgtga actcacaaat tgatatttat
     5281 atacctataa aataatctat aagaaaacta aaagataatt tgattaagaa atagatgttc
     5341 gtaaaagagc atctattttt tatttttata agatttagat aattttaata ataaaagaaa
     5401 taaaaatata ttataaaaac aatttgattg gaattttcag aaaattaatg ctataattaa
     5461 aagtaaattt aaagggaggt tataaaatgg ctaaattaac tctagaacat ataaaaggaa
     5521 atacatatta tattccactc cctacaatag taggtgtata cgtagatggt aaagatgcaa
     5581 ttttaattga cagtggaaat aataaggata cagctagaca agttttaaga ttattagaag
     5641 aacataattt aaatcctaaa ttaataataa acactcattc aaatgcagac catataggag
     5701 gaaatgcata tttgaagaat caaacaaaat gcaagattgc tacgactaaa attgaaggat
     5761 attttacaga aaatccaata ttagaatcag catttttata tggtggctat ccaagtaaag
     5821 cactgaagaa taaattttta ttagcaaagg aaagtgaagt tgattatatt ataccttcaa
     5881 atggcaaaat tgtagataca gaacttgaag cgatttctct tccaggtcat tattttgaaa
     5941 tgattggtgt tagaactcca gataatgttt tgtttgttgc agatagtctt acaccagaga
     6001 atataattac taaatatcat tttttcttcc tactggatat agattcacag tttaagacac
     6061 tagaaaaatt gagaatgtta gaggctgatt tctttgttcc aagtcactct gtcaaaacta
     6121 cagatataaa aagtttgatt aatattaata agaagaagat ggaagaaata atagataata
     6181 ttaaaaaggt ttgttatgag ccagttatga ttgatgaagt tattgaaaaa atgtgtgatt
     6241 tgtacaatgt caagcttgat gctaatcaat atgtgttggt tggaagtaca atacgttctt
     6301 atataactta tttatatgag aataatatgg ttgaatatat atttgatggt ggtaagatga
     6361 tgataaaagc tgtgtaaata gtaataattt tcaaattata tgatgaaatt gttttagtat
     6421 gactgttatt tgaaaagtaa tataaaaaaa tttatataaa taagctaaga tgattgatat
     6481 aaagttactg ataattttaa ggtaatatat acgttactat aatattatgt tattatttgt
     6541 aaataagggg ataatttata agcaaattaa agaccttaat ttacaggagg aatagtgtat
     6601 attatgaata aaaaattcaa aaaattcagt aaaaaactaa gtatattaat tttagttttg
     6661 actatgtttc tttttaataa tttaactgca aatgcacaga ttaaagaaga ttcaataata
     6721 ggaattgata gatatgaaac agcaggactt atagcggata gacaaactta tgatactgta
     6781 atattagtta atggagataa aaatttatct gatgggcttt catcaagtgg attagctgga
     6841 gctattaacg caccaatact tttgactaaa aaaagtgaaa taccaaaagc tactttaaat
     6901 agactagata ataagagttt aaatgatgta aaaaaagtat atataattgg tggttataat
     6961 actattgaaa attcagtaga aaaagatata aaaagaaaag gtattcaagt tgaaagaata
     7021 aatggtaaca atagaattga aactagttat aatgtagcta aaaaaataaa tgaagtaagt
     7081 agtgtaaaag aggtaatgct tacaaatgga tttgtaggag aggctgatgc tatgagtata
     7141 gcacctgtag ttgcaaaaaa taaaggagct ataatactta cagatgggaa atcagttcca
     7201 tttaagactg aaggtttaaa tgtttacgct ataggtggca aatctgcgat aaatgaggat
     7261 ttagtaaatg aaactaaagc aactagaatt ggaggaaatg atagatttga gaccaataaa
     7321 aaggtaatgg aaaagtttta taatggagcg acagattttt atataacaaa tggatatcaa
     7381 ttagtagatg cactaacatt atctccttta gccaaagaaa aaccaatcgt tttagttgct
     7441 gatggaagta ataaaggtat tttaaaagga gctaaaagta taacaaaagt tggaggtatt
     7501 gatgccaata tatataaaca gtgtttagat atgattaaat ataataatat ggatataact
     7561 ccaaatattt taaaacactt aacttcagtt gaaggaaatg aagtttctga aatacttata
     7621 gaatcagata atttaggtgt ggttgttgaa aagacgaata ccaataaatt tgagtttgat
     7681 tatgtaagtg taactaatga aaaaaattgt actttttctg tatataaaga aaattcttct
     7741 aataatataa aaaatggaaa gctagttgta agtgctaaga aaaaaataga taagaaagat
     7801 agtgatttgc aagatatgaa tggcgacaat atgataaatg caaataaaga taggatggta
     7861 aatgtgataa aaattggagt tcccgataaa atgtattcta attttaaagt agatgttgaa
     7921 agtggttcag tagaacttta taatattaaa ggaggagcta ctgttgatgt caatgacggg
     7981 attgctaaca ttgttgataa caatgtaaca aatcctttca atataaatac taatagtggg
     8041 atttcaggtg taacagctga aactatatca tctgaaataa aatttagagc aaacaatgga
     8101 attgtaaatg taacagctac gaatataaat ggcaatataa gtttatttgg aagcgataat
     8161 aaaggtacct ttgatggaat atttaaatta aatctgaaaa aagaaccatc aaatttacac
     8221 ttgaagttaa ttggaaatgg gataaataaa ttgccagaag gttggtctaa agattatatt
     8281 ttaggaaatg gacaaccaat tattgaagtt aaaaataatg gcataaataa tatatcaatt
     8341 ggagaataaa aacatatgaa aataaagttt at
//
LOCUS       DAEPXW010000137         8224 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.141, whole genome shotgun sequence.
ACCESSION   DAEPXW010000137 DAEPXW010000000
VERSION     DAEPXW010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8224
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.141"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(88..1035)
                     /locus_tag="KRM55_003333"
     CDS             complement(88..1035)
                     /locus_tag="KRM55_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595540.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGYIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
     gene            complement(1063..1554)
                     /locus_tag="KRM55_003334"
     CDS             complement(1063..1554)
                     /locus_tag="KRM55_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595541.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            complement(1997..2890)
                     /locus_tag="KRM55_003335"
     CDS             complement(1997..2890)
                     /locus_tag="KRM55_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH1595542.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            complement(3115..5400)
                     /locus_tag="KRM55_003336"
     CDS             complement(3115..5400)
                     /locus_tag="KRM55_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH1595543.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHIKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLLYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKIIVYGKKYILEKCIKIDK"
     gene            complement(5397..6077)
                     /gene="pgmB"
                     /locus_tag="KRM55_003337"
     CDS             complement(5397..6077)
                     /gene="pgmB"
                     /locus_tag="KRM55_003337"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH1595544.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            complement(6301..8184)
                     /locus_tag="KRM55_003338"
     CDS             complement(6301..8184)
                     /locus_tag="KRM55_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBH1595545.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
BASE COUNT         2625 a         1397 c          727 g         3475 t
ORIGIN      
        1 catttatata tatgataaat atatcaatat ctattttcct ttaaccaaat gctattttaa
       61 taagtttaag ttttagcttt aaaatactta ataatacaat aaaagtgatg tatttacaaa
      121 taattcttct ggatttaatt catttattga tgtatgttca atttttatat ttatattttt
      181 catatcttca taaataattc caactggaga acaaatgaaa caagaaaatc caaaagtttt
      241 tgttattttt tttaccttat tatcaccaaa acttatttgc tttttacaat cgtttatatt
      301 ttcattgtta ttttgtatat catttttata atacttatct tttttaatgt cattagactt
      361 atttactgtt ttaaaattac tcctattttt acaactatag tctatttcaa cttctatata
      421 cccaaaaact atcaagttac ataatttcaa attactacct ttgtttataa gatttttcat
      481 aggtttaaca tcaaatattt tactatttac atttactttt aatatatctc ttagattttt
      541 aggagctttt aaagtattac ttatattcaa ttgtttgaat acaattttat ttacattagt
      601 ataaactcta ttactttcta ttgatattct tgttgggaat ttatctagat tacacttata
      661 ataatagtat atattagcac tattctttat aatcctatgt gcagaatttg gtaaaactac
      721 actcttaaaa gatattattt ttttacaact tgcatctatt ctccctatgt aaaaaccttg
      781 ctgtgggtct aatccacgtt ttataatgcc attaactttt accgtattat ttataaactc
      841 tatatattta gaaatataat ctttgaaaaa tatatttcca gttttgtacc tacttgtatt
      901 tgtaacaata atagtgtagg tcaaaatctc aaatacagat gcacattttt tatcaacata
      961 tttttctact tttataatac ttccatttgc atcatttgaa aatacatcat taaaagtagt
     1021 tttcgttatt ctcattgcat ccacctttct ataatttaaa gattactcta tcttggaact
     1081 attttcataa cttataattg cagtaacact aataaataaa ttatcatcta aaatagatga
     1141 agtaatatct tgtataagat actttaaatt aattttatct ttattttcta tctttctagg
     1201 catttgtata aatgtactaa agggtatttt taatttaaat gtattttttt tactagaatt
     1261 tctatttctt ttattgcctg cataatctaa tattgcatca atatctatat caccaactaa
     1321 aatcaacttc tttcctgtaa gttgttcatc ttctaatgat atacattcta tagtatcaac
     1381 aagacttata ttgttaatat tcatattgta aacatatgtc tctaatgaat ttattacagt
     1441 ttttttagaa gctaatttaa aatttttata tgtattaaat tgagataaat aaagagtctt
     1501 ttctagtttt tcacatcttt caaggttgta tattacctta ttattttcat acataatcgc
     1561 atcaatctcc ctgtatctat atattaatac tattcataaa aattatttca aattaccatt
     1621 ttttattatt cactatctag ttgttattta cttttaagaa agaatccttt tttacttcat
     1681 tgatttcaat ttacaagtaa aagtctttct gaaaaaaaaa tatatatatc tctattcact
     1741 tttttataag taattataat ttttatagac taacggtcag ccttaaggga aaaggtgttc
     1801 tttaagtgca gaatttagat aaagtaaata atccttttat aaataattcc aagttttaac
     1861 ttaaataatt tgatttacag tataaagtaa attttgaaag ataatgatat cgatttaata
     1921 attacaagta aaagcatgtc aaaataaggc tatgatttta aaaatcatag ccttatcaat
     1981 aaaaatttaa tcaaagttac atttcacttt gaatttcact gtctattaat tgaagattat
     2041 actgttgaat taattctatt agacgagctg catatatact attgccattt tcatccttcg
     2101 cagtactata acctgccttt tctaatgctt tagcttgata tatatacgtt tttgcatcaa
     2161 atacaccatt gtttttatac cttttatttg tggctaaaaa ttttgcatgg tcttttatag
     2221 attcattttt atcatcatat attctaaatt tatcatctat aattgtatct aaatgttctt
     2281 tcgtttctaa agtcactgac ttgcctttcc aataagcgtc agcctttata ccaaatagat
     2341 tgttatattg ttttgccaaa gttgacttgc cccagctaga ttctattata gcttgtgcaa
     2401 tagttataga tggaagtatt ttataatcct tataattttg tattgcttct gttttaattt
     2461 catcaataaa cttcatatat tttgtatcag acttcaatct ttctggtttt ataccataat
     2521 ccttaagatt gtctatataa ttatcaacca atcttttttg tctattacta aattctaact
     2581 catccaaaat atcacttaac ttatttattt tattattttt agaaaaattc ttaacaaata
     2641 aatctgatac ttcttgtatc tgtgaatcct taacgttttt taagttattt ttatttaaca
     2701 cagcaacaat ggaagctaca tacttccagt taacttgtgc attattttta cttgctaaat
     2761 cagcatattt tatatactta ctgacattta tatcatcctt ttttatctct ctagatgaat
     2821 attccttcac taatacacct attaaaattg atattatcag tattataaca atgaattttt
     2881 tattcttcat aaatattgtc ctcccttata ctatctgctg aatataatat accttacttt
     2941 tgtgacatat tctttacgaa attttgaaga ttttatgaag atttatgaaa tatatttaat
     3001 taaaagcact actattgtta taatatatag ttttctatca cacaaaatag ttaaaataaa
     3061 taaataatta gatagcttat tttaactatt tatataataa aaatattatt aaatctattt
     3121 atcaattttt atacattttt ctaatatata ttttttccca tatacaataa tttttattgg
     3181 tttacctttt aaattttcta ttttaattaa atcactacat acatctacat taataatatt
     3241 atctctataa tttatattga aagaataatt tttccactct tttggcaact tagggtcaaa
     3301 agatagagtt tcattccatg ttctcatgcc tgcaaatcca tgtacaatgg aaagccatga
     3361 accagacatt gaagttatgt gcagtccatc atttgtatca ttattgtaat tatctaaatc
     3421 aagcctagct gttcttgaat ataattcata agccttttct aggttatcta tttctgaggc
     3481 aataatagaa taaatactag aagataaaga agattcatgt acagtatatt tttcatagaa
     3541 gtcaaaattt ctcttttttt cttctttagt aaatctattt ccaaaatagt aaattccctg
     3601 taatacatct gcttgtttta taaaacacga cctaagaatc ttatcccaag accaattttg
     3661 attaagagga aaattttctt ttggtaaatc ctttacttct acaaattctt tatctaaaaa
     3721 attatcattt tgaattatta tttgtagttc ctcatcatac agcagataca ttttatttga
     3781 tattattttc caaaactcaa cttcttccct agtcacatta tttctgtcaa tacattcatt
     3841 acactctttc tctaatcgta agatattttc tacagcataa tctaaacacc atttagctat
     3901 ataattagta taccaattat tattgatatt gttttcatac tcgtttggac ctgttactcc
     3961 atgtatcata tacaaatctt tttttgtaga caaatgaact ctacttgccc aaaatctagc
     4021 tatttctatt attacatcta ttcctttttc ttttatatat ttatagtcac ctgtataatt
     4081 tgtatagtta tatattgcat atactatact tccatttcgg tggatttcct caaatgttat
     4141 ctcccattca ttatgacatt ctactccatc aaatgttacc attggatata aagcaccttt
     4201 aagacctagt ttttttgcat tatcctttgc ctgttctaac tgattgtacc tatattctaa
     4261 aagatttcta gttacctcct tatctgctac acctagatat actggaacac aaaacgcttc
     4321 tgtatcccaa taagtagctc ctccatactt ttcaccagta aatccttttg gacctatatt
     4381 taatcgcgaa tcttctccat aatatgttga aaatagttgg aataaattat atcttatacc
     4441 ttgttggcta cttttatctc catttatttt tacatctgca ctttcccatc ttttattcca
     4501 taactttata tgttcattta atatatcatc ataactttta gatagttctc tatttaaaat
     4561 gtcttcacat tttcttaata gctcactttc cttataatct ctagttgagg ttatagatac
     4621 atatttttct atacttgcaa cctcattttt taaaacatcc attgttatcg aattttcaca
     4681 gtaattataa tcactctcat gagatacagc ttctacatca ccatttgtct taatatacat
     4741 cattgaaccc acagtgaata ctggtgtatt aaatgcattc tcctttgttc gagaaagaat
     4801 actcccttta tattctaaag aacttgaaga aattccattc caaaactttt cctcatagtt
     4861 tgaatcttca ttttttatat ttgaatctaa atatggtaca aattttattt tagtattaga
     4921 atttaatgat tttatactgt atttaattac tgcaagttcc ttaacagata tacttaaaaa
     4981 cctagtaacc ctaacttcaa attttttatc atttatattt acaataaacc tacgatttaa
     5041 aataccattt ttcatatcta attctctatg aaaatcttct actttacatt ttgctaaatc
     5101 taattctaca tcatctatga aaattcttac acctatatag ttgactgaat taggaatttt
     5161 accaaagtat tctggatacc catttttcca ccaaccaaca cgagttttat ctggaaacca
     5221 tactccagct atataagacc ccttgtgtgt atctccacta taattttcct catagtttcc
     5281 tctcataccc atatatccat tgcctatact cattatggac tctgctaatc tattttcttt
     5341 gatttcaatc ttatcttgta taatcttcca ctcatctaca ttactaaata aacatttcat
     5401 ataattctcc taactatata ctcattatac ttttcttgta tatattcaaa ctttaattga
     5461 tttgttgaat ctacaactaa atttgctttt tttaagtttt cataatttcc aacaccaaca
     5521 gaaaacatat tagctgagtt tatagcgtct atacctgcac ttgcatcctc tatccctatg
     5581 caattttgtg gatttacatt aagccctttc gctgacataa gaaatatctc tggatgtggt
     5641 ttattgtttt tacattttcc tgcatcagct ataaaatcaa atttgtcact tatacccaaa
     5701 tgatttaata catttattgc attcttactt gcagaagata gacctatctt tatattatta
     5761 gattttacat caattaacaa gctttctatg cctggcaaaa tatcatttga agttatctca
     5821 tctatcaatg atacatagta attatttttt tcttcagcca ttctcacttt ttcttcttct
     5881 gaaaatgaat atttcttatt tccaaattct aatatcctgt ccaatgactc cattctactt
     5941 atgcctttta aagattcatt aaattttgtg tctatatcta tcccaacttt atgagctagt
     6001 tttctccaag ccatatagtg ataatatgca gtatctgtaa ttacaccatc taaatcaaat
     6061 ataaatgctt caatcattct tatttcctct ttctacaaga aatttttaga ctaataatca
     6121 atttattttc tatcttgtat ttaagatatt atttataaaa ttatctactc taactcagtc
     6181 tttaatttaa aatctacttt caattcactc acttgtagac catatttttt atcgtttata
     6241 aagacttgtt taaactgtat aataatttaa catgaaatct aaaataaata cttttttgta
     6301 ttattttaaa ataatgaact tgtatttctc taacattagt tcttctttta aatcaactat
     6361 ttcttcttca tataaatctt ttactttttt atttgctaaa taatctggta acgtcaaaat
     6421 tatattttta gatgaattat ttattattat agaaatagat tcttttttca atataatcgt
     6481 tccattttcc ttatctgcta acacccattc atttgatata gacctaagtt ctttattttc
     6541 tttacgaagt ctaataatct tcttcataaa atcaaatata tccttattcc atttttcttc
     6601 attccattcc atacattttc tttgaccttc agatattgaa cttaattctc cttccattcc
     6661 gatttcatca ccatagtata tacaaggaca tcctgtttgt acaaacataa acatatatgc
     6721 aagtttaaat ctatcaatat ttccattagc ataagtcaat attcttgtag tatcgtgact
     6781 tccaagtaaa ttaaaaataa cttcactaac ttgtattgga taacttacca ttacatcatt
     6841 tatcatatac ttaaattctt cggcgtttat ctcatctgta caaaagaatt ttttcatggc
     6901 ttctgacatc aagtaattca taactgaatc aaattggtca cccattaacc atggtaaact
     6961 accatgccaa atttctccca atatataaat gtctggtttt acttttttga cttcttctct
     7021 aaactttctc caaaaaacat ggtctacttc atttgaaaca tctaatctcc acgcatctat
     7081 atcaaattcc tgtatccagt acttgcctac atccaataaa tattttatta cttctgaatt
     7141 ttctgtatta agtttaggca tatatttttc acacccaaag gtttcataag gtatattttt
     7201 ttcatctatt tgttctattg gagtatcaat tttactcata tcttttatat aaaaccagtt
     7261 tttatatcga gaattttcct tattttgaac tacatcttgc cactgtttag aataatatcc
     7321 tatatgatta aaaacagcat ccaacattat ttttatattt ctcttatgcg cttcttctat
     7381 tagttttttt aaagtctctt tatctcctaa tgtagggtct acctccatat aatctaccgt
     7441 atcatatcta tgattggttt ttccaattgt aatagggcaa aagtaaattc cgtttattcc
     7501 caaatcactc aaataatcta agtgttctat cacaccttgt aaatctccac ctgtaaaatt
     7561 atctctggtt ggaatagctc cccatttatc tactccttct gggtttatag acgggtcacc
     7621 atttgcaaat ctatctggaa atatctgata ccaaacagta tctttcaccc aatttggcac
     7681 tttaggtata tctatataat ttaaatatgg atatccaaaa aaattaccta tttcacataa
     7741 ttccttttca tcattttcat ttcccaactc tattattctt ttttctgtaa ataaaagttt
     7801 ttcctcttga ccttctatta taaagccata tcgtgagcgt ttatttaaag gcttacactt
     7861 agctatccaa tagtcaaata attcagtttc tacttcttta ctcattacta tatttgttcc
     7921 accagaccaa ccaactccag atgcatttaa atttcctcct cctgcacctc ctttatccca
     7981 cacatattgg tctcctattc gtaaaattac tcttttcgct tcattttttt tagttctaag
     8041 tcttatatgt agtgtttctc tatcataacc ataggcataa ttgctcattg gtatatgtaa
     8101 tatagcttct tttgttaaac tattttgaat tgttcctttg atttgattac ttaaagttat
     8161 attttcttta tttttattag acattttaaa atttccctcc tttataataa tttatataat
     8221 ctaa
//
LOCUS       DAEPXW010000138         7912 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.142, whole genome shotgun sequence.
ACCESSION   DAEPXW010000138 DAEPXW010000000
VERSION     DAEPXW010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7912
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.142"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            27..101
                     /locus_tag="KRM55_003339"
     tRNA            27..101
                     /locus_tag="KRM55_003339"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KRM55_003340"
     tRNA            116..200
                     /locus_tag="KRM55_003340"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KRM55_003341"
     tRNA            210..293
                     /locus_tag="KRM55_003341"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="KRM55_003342"
     tRNA            317..391
                     /locus_tag="KRM55_003342"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="KRM55_003343"
     tRNA            416..492
                     /locus_tag="KRM55_003343"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            500..575
                     /locus_tag="KRM55_003344"
     tRNA            500..575
                     /locus_tag="KRM55_003344"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:533..535,aa:Gln,seq:ttg)
     gene            584..659
                     /locus_tag="KRM55_003345"
     tRNA            584..659
                     /locus_tag="KRM55_003345"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:617..619,aa:Lys,seq:ttt)
     gene            662..750
                     /locus_tag="KRM55_003346"
     tRNA            662..750
                     /locus_tag="KRM55_003346"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Ser,seq:tga)
     gene            754..829
                     /locus_tag="KRM55_003347"
     tRNA            754..829
                     /locus_tag="KRM55_003347"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:787..789,aa:Phe,seq:gaa)
     gene            836..909
                     /locus_tag="KRM55_003348"
     tRNA            836..909
                     /locus_tag="KRM55_003348"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:870..872,aa:Met,seq:cat)
     gene            924..1000
                     /locus_tag="KRM55_003349"
     tRNA            924..1000
                     /locus_tag="KRM55_003349"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:958..960,aa:Ile,seq:cat)
     gene            1018..1094
                     /locus_tag="KRM55_003350"
     tRNA            1018..1094
                     /locus_tag="KRM55_003350"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1052..1054,aa:His,seq:gtg)
     gene            1103..1178
                     /locus_tag="KRM55_003351"
     tRNA            1103..1178
                     /locus_tag="KRM55_003351"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1136..1138,aa:Lys,seq:ttt)
     gene            1186..1259
                     /locus_tag="KRM55_003352"
     tRNA            1186..1259
                     /locus_tag="KRM55_003352"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1218..1220,aa:Cys,seq:gca)
     gene            1267..1343
                     /locus_tag="KRM55_003353"
     tRNA            1267..1343
                     /locus_tag="KRM55_003353"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1301..1303,aa:Arg,seq:acg)
     gene            1356..1431
                     /locus_tag="KRM55_003354"
     tRNA            1356..1431
                     /locus_tag="KRM55_003354"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1389..1391,aa:Val,seq:tac)
     gene            1507..1920
                     /locus_tag="KRM55_003355"
     CDS             1507..1920
                     /locus_tag="KRM55_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595546.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVYGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2229..5660
                     /locus_tag="KRM55_003356"
     CDS             2229..5660
                     /locus_tag="KRM55_003356"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBH1595547.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5902..7830
                     /locus_tag="KRM55_003357"
     CDS             5902..7830
                     /locus_tag="KRM55_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH1595548.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
BASE COUNT         3100 a         1012 c         1588 g         2212 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatatt ggggattagc caagtcggta aggcacatga ctttgactca
      541 tgtatgcgta ggttcgagtc ctgcatcccc agccaaacag tatggtctat tagctcagtc
      601 ggtagagcac ctgactttta atcagggtgt cccgcgttcg agtcgcggat agatcaccaa
      661 tggagaggtg tccgagtggt ttaaggagct ggtcttgaaa accagtgact tcgaaagggg
      721 ccgtgggttc gaatcccacc ctctccgcca aatgcccaga tagctcagtc ggtagagcag
      781 gggactgaaa atccccgtgt cggtggttcg attccgcctc tgggcaccaa aatgtggcgg
      841 tatagcttag ttggctagag cgttcggttc atacccgaaa ggtcataggt tcgactccta
      901 ttaccgctac taaaatttaa tgtgggccat tagctcagtt ggttagagcg cccggctcat
      961 aaccggtagg tctggggttc gagtccctga tggcccacca cattaaatta acttatggtg
     1021 ggtatagctc agttggttag agcgccagat tgtggctctg gaggtcgtga gttcgactct
     1081 cattatccac cccaacttat atggtctatt agctcagtcg gtagagcacc tgacttttaa
     1141 tcagggtgtc ccgcgttcga gtcgcggata gatcaccaaa aaggcggcga catagccaag
     1201 tggtaaggca gtggactgca actccttgat ccccagttcg aatctgggtg tcgcctccaa
     1261 taaaatgcgc tcatagctca actggataga gtgtctgact acgaatcaga aggttagggg
     1321 ttcgagtccc tttgggcgca ccatatgaat agcgagggat tatagctcag ctgggagagc
     1381 acctgcctta caagcagggg gtcacaggtt cgagccctgt taatcccacc agtgcaaacc
     1441 tctagtaaaa ctactagagg ttttattttt gattgaaaaa atttttatat ttaggaggta
     1501 aaaaatttgt atatagtaat aggaaatgaa atagttgata gtgaagaact taaaataatt
     1561 atagataaaa atagtgaatt taaagttgaa aaagatttaa gtaaaagcac aaaaagagaa
     1621 gatgtaatag catatcagtt aagtatagat ttaaattacc tagattctct tataaatgag
     1681 caatgtaatt tagccagtct atctgatgaa gagaaatttg atgaatatat gactttgtct
     1741 gatgaacttg cactggattt agaagagtta atgccaaaat atacaataat aaatgctaga
     1801 gcatataaat tagacgaggt atatggaatt gtaaaaataa tactagctgt agcgtatgca
     1861 gatttagggc acttaaaact ttctgatgta gtaaagaggc tatctagaca agtagattag
     1921 gatatgaata tgaactatat taaaaaaatg tataaaatct tacgtaaaga tgaaaataat
     1981 tatgtaaaca tagaaaaaaa cagtataaaa tcaagtcaat tgtagaaatt ttcacataaa
     2041 ttcatctgaa attctataaa aaatgcctta attttaatga ggtaaatcga gtttacacag
     2101 tctaaaaatt acttatattt ataaatttat cttattaatt aaggaacttt cttaaacatc
     2161 ttcaaaaata aagtatttta gtctataatc tttaatatta cacaaacaat aaaggagaag
     2221 aatagagtat gcttaaaaag tttaataaaa tactagtggc taatagaggc gaaatagcta
     2281 taagaatatt tagagcctgt tcagaattgg ggataaaaag tgttggtata tacagtaagg
     2341 aagataagta tggattgttt agaacaaaag cggatgaatc atatttgata ggagaaggta
     2401 aagggccaat agatgcatat ttagatatgg atggaataat agacctagca aagagaaaaa
     2461 aagttgatgc tatacatcca ggatatggtt ttctagcgga gaatgcagaa tttgctcgta
     2521 aatgtgaaga gaatggaatt acttttatag gaccatcatc taaggtaatg aatatgatgg
     2581 gggataagat taactctaaa aaaatcgcaa aagaagttaa tgttcaaact ataccaggag
     2641 tagaaaaagc aataagaagt actgaagaag caaaggaagt tgcaaacaaa ataggatatc
     2701 ctgttatgat aaaagcatct aatggcggtg gcggtagagg tatgagaatt gtacatcgcg
     2761 aagaagactt agagcttgaa tatgaaactg cttgtagtga atcaagaaaa gcttttggag
     2821 aagatattat atttatagaa aaatatatag ctgatccaaa acatatagaa gttcaaatat
     2881 taggtgataa ttatggaaat atagttcact tatatgaaag agattgttca gttcaaagaa
     2941 gacatcaaaa aataatagaa tatgcaccag ctttttcgtt agatgataaa gtaagaaaag
     3001 agatatgtga agatgcagtt aagttatcaa aacatgtggg ttattctaat gcgggaacat
     3061 tagaattttt agtagatgca aatggtgggc attattttat agagatgaac acaagagtac
     3121 aggttgaaca tactgtaaca gagatggtta caggaataga tatagttcaa agtcaaatac
     3181 taatagccca aggttacagc ttagatagtg aagaaattaa tataaaatca caagatgatg
     3241 tggaaataag aggttactct atccaatgta gaataactac agaagaccct aagaataaat
     3301 tcatgcctga tacaggtaaa attcaagttt atagaactgg ttcaggattt ggtataagac
     3361 tagatggagg aaatggattt acaggggcaa acataagtcc tcattatgat agtttattgg
     3421 ttaagacaat atcttgggat agaacattcc aaggagcaat aaataaaact ataagatcta
     3481 taaaagaact tagagttaga ggtgttaaaa ctaatgtagg attcctagtt aatgttttaa
     3541 ataatcctat attctcaaat ggtaaatgta gtactaagtt tatagatgaa aatccagatt
     3601 tatttgaaat aacagaaagt aaagacagag gaacaaaatt acttcaattt ataggagatg
     3661 taattgtaaa tgataatgct tgtaaagaaa aaccattatt tgatgcatta catgacccaa
     3721 gaatggataa ggatggttca aaatcagaag gaagtaaaat acttttcgat aagttaggta
     3781 aatctgcata tatagaaaag ataaaaaatg ataagaaatt actattaaca gatacaacaa
     3841 tgagagatgc acatcaatca ttattagcaa caagaataag aacatatgac ttattaaaag
     3901 ctgctaagcc aacagaaaaa tatcaaaagg atttattctc acttgaaatg tggggaggag
     3961 ctacttatga tgttgcatat agatttttaa aagaatctcc ttggcgtaga ttacaaaagc
     4021 taagagaaga aataccaagc ataatgttcc aaatgttgct tagagcatca aatggagttg
     4081 gatataaaaa ctatccagat aatgtaatag aagaatttac aaaagaatct gctagacaag
     4141 gtatagatgt atttagaata tttgattcat taaactgggt tgaaaatatg aaaccatcta
     4201 ttaatacagc tttagaaact ggaaaaattg ttgaagcaac tatgtgttat acaggtgata
     4261 tactagataa gactaaaact aaatacaatc tagaatatta tattaaaatg gcacaagaat
     4321 tagaaagctt gggagcagat ataatagcaa taaaagatat gtcaggtctt cttaaaccat
     4381 attcagctta cacactagtt aaagagttaa agaaaaatgt aaaagcacca atacatttac
     4441 acactcatga tacaagtgga aatggtgtag caacttgttt aatggcgtca gaagctggag
     4501 tagacataat tgatgctgca ttagaatcta tggcaggact tacaagtcag ccatcactta
     4561 atgctatagt agaggcactt aagaatacag agagagatac aggaatagat ttatttggat
     4621 atgatgagtt aggaaaatat tataaggatt taagaaaagt ttataataaa tttgaaagtg
     4681 atttaactaa ttcttgtgca gaaatatata attttgaaat accaggaggc caatatacaa
     4741 acttaaaacc tcaagctgat agtttaggat tagttaatag atttgatgaa gttaaagaaa
     4801 aatataaaga agctaatgaa gttgtaggag atataataaa agtaactcca tcttcaaaag
     4861 ttgtaggaga cttagctatc tttatgacta aaaataaatt agataaagat aatataatag
     4921 aagaaggtaa aaatttatca ttcccagatt ctgttgtgga ttactgtaaa ggtatgattg
     4981 gtcaaccaga aggtggaata ccaaaagatt tacaagaggt agttctaaaa ggtgaagaag
     5041 ctataacagt aagaccaggt tcattattac cagcagaaga ttttgatgaa atagctaaat
     5101 atctaaatga aaagtatgat ataaatgcta atataagaaa tgttataagt tatgctttat
     5161 atccaaaagt atatgaagat tatatcaaac atctacaaca ttataatgat atatctaaac
     5221 ttgaaagtga tgtattcttc tatggattaa ataaaaatga agaatgtgaa gtagaaatag
     5281 aagaaggtaa ggtattaaca ataagattag ttgaaattgg tgaagttaag gaaaatggat
     5341 ttagaactat aggatttgag ttaaatggaa tggttagaga agtagaaata aaagataaga
     5401 atttctctgg aaaaattaat aatgttgaaa aagctgatat gaatgaccct cttcaaattg
     5461 gagcaagcat accaggaaaa gttataaaaa taatggttaa agaagaagat gaagtaaaag
     5521 caaatcaacc attaatcgtt atagaggcta tgaagatgga aactataata gttgctaaga
     5581 ctgatggagt aattaagtca atcaaagtaa aagaagatga tatggttgaa gataaacaat
     5641 tattaatgat aatgaagtaa tttaattaaa ataaattaaa aagcactctg aaatgtttaa
     5701 taaaaaatgt tttagagtgt ttttatttat tttaattaaa tatttgttaa aaaaaagagg
     5761 acaattacct ccagatgtag aaataaagct agtaaggaaa atgttatcta aaaattctaa
     5821 atatagtaaa tattttccat aatatttctt aggaaataac agcaaagata aaatacataa
     5881 atttaaaagg tgggtgctta tatgaaggtt tatgatagta aaatgttgag aaatgtagcg
     5941 gtattaggac atagcggatg tggaaaaaca aatctaatcg aaactatagc ttacacagca
     6001 aacactaata agatacctaa attaacagac aaggtaaata tgacttatag catgggatta
     6061 atacctatag agtataatga ttataagttt aacttattgg ataccccagg atattttgac
     6121 tttagcggag acgttgtgtc atctcttaga gcaagtgatg cagcaataat agtaatagat
     6181 gcaacagcgc ctattcaagt tggtacagag aaatcattag aactaactga gagtattcct
     6241 aagataatgt ttataaataa aatagataat gaaaaggcaa gatacaaaga tgcaatagca
     6301 atgttaagag aaaaatacaa taataagata gttcctatga taagtcctat atacaaagat
     6361 aaaaactttg taaagttaca taatgttttt gaaaacatag atgatttaga aggtgaattt
     6421 aaggaacaag ctatgagtgt taaagaagca ttaatggaac ttatagcaga aactgatgac
     6481 caaatattag ataaatattt taatggagaa gaactaacta cagaagagat acaaaaaggt
     6541 attattatag gtatacaaag aggtgatatt atacctgtaa tatgtggttc aactataaat
     6601 aatataggca caaaggaaat attagataca atatcaagtt atttagaacc tatctttaca
     6661 gaggaaagca aaccatttag gggattagta tttaaaacta tggttgaccc atttgttgga
     6721 aagatgtcat atataaaaat tactgagggt gtactttcta aggataaaga tgtttttaat
     6781 ataaataaaa atgtaaaaga aaaaatagct aatatatata cattgagaaa tagtgaatta
     6841 gtagaaatag aaaaagctaa agctggtgat atagtagtta taactaaagt taattctcta
     6901 aaaacaggag acactatatc tgcagataaa gatgcagaag ctttagaaaa gatagatttt
     6961 cctaaaccac aaatatatta tgcagtaact cctaagaata aaggtgatga agaaaaagta
     7021 gcatctgtat taaataaact agtagaagag gaccctacat tacattggta tagaaataca
     7081 gagacaaaac aagcactttt aggaggtcaa ggagaacttc atataaaaac aattaaaaat
     7141 aaaatgaaag ataagtttgg tgttgatgtt gaattgaatg accttaaagt tccttataga
     7201 gaaactataa aaggaacagc tgatgtacaa ggaaaacata aaaagcaatc aggtggtcat
     7261 ggtcaatatg gagacgtaaa aataagattt gaaagatgtg aatctgattt tgaatttaca
     7321 gaagaaatat ttggtggttc tgtaccaaaa caatatatac cagcagttga aaaaggttta
     7381 aaagactcta tgcaaaaagg tatattagca ggatatcctg ttacaaacat aaaagctacg
     7441 ctttatgatg gttcatacca tgatgtagac tcttctgaaa tggcctttaa aatggcagca
     7501 agtgcagcct ttaaaaaagg tatggaagaa gcacacccaa tactactaga acctataatg
     7561 aaacttaaga taactgttcc agaagaatat atgggagatg tcatgggtga tataaataag
     7621 agaagaggaa aaatatttgg aatggaacca gatgacaaag ggaaacaaat aatatttgca
     7681 gaagctccac aagcagagac atttaaatat gcaatagatt taagagcaat gacacaaggt
     7741 agaggatact ttgaaatgga attagagaga tatggagagg ttccatcaca gtttgcagaa
     7801 aaaataattg ggctagctac tgcaaagtaa tgaacaaaat aaatagaaaa ataattaata
     7861 tatattatta aaaatatttt tagggtttta actaggtata ggtttatgtt ag
//
LOCUS       DAEPXW010000139         7851 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.143, whole genome shotgun sequence.
ACCESSION   DAEPXW010000139 DAEPXW010000000
VERSION     DAEPXW010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7851
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.143"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     misc_binding    109..320
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            483..1772
                     /locus_tag="KRM55_003358"
     CDS             483..1772
                     /locus_tag="KRM55_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH1595549.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            1826..2905
                     /locus_tag="KRM55_003359"
     CDS             1826..2905
                     /locus_tag="KRM55_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBH1595550.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            2926..4470
                     /locus_tag="KRM55_003360"
     CDS             2926..4470
                     /locus_tag="KRM55_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020246462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBH1595551.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(4633..5175)
                     /locus_tag="KRM55_003361"
     CDS             complement(4633..5175)
                     /locus_tag="KRM55_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBH1595552.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(5323..5607)
                     /locus_tag="KRM55_003362"
     CDS             complement(5323..5607)
                     /locus_tag="KRM55_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1595553.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(5670..6434)
                     /locus_tag="KRM55_003363"
     CDS             complement(5670..6434)
                     /locus_tag="KRM55_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH1595554.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(6716..6982)
                     /locus_tag="KRM55_003364"
     CDS             complement(6716..6982)
                     /locus_tag="KRM55_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1595555.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCLVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(7024..7833)
                     /locus_tag="KRM55_003365"
     CDS             complement(7024..7833)
                     /locus_tag="KRM55_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595556.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         2733 a          998 c         1283 g         2837 t
ORIGIN      
        1 gaaaatttac atataaaact aaaaaatgca agtaattgac tttttaagtt gacaaaatat
       61 tgcatatata ttatgatata aatcataaat taactacaaa tcaatattat atattcgtag
      121 aagaagaaag tagcataaag gaattttaca gagagttaga tttggctgag aactaatatt
      181 ggaatttatg tgaaaaggac tttggagaat actattgtaa ttatgttaga atagtggttt
      241 aattcgcctt aagaaaatga gtgagtaaaa ttaattttta ctaataagag tggtaacacg
      301 gatttatatt cgtctcttgg atttttccaa gaggcgtttt ttattataaa cttatttcag
      361 aaaatttaaa actatatatt aaatgaaaat tataaaaata tgatagttaa taaatttata
      421 aattagaaaa ttgtaaaata tgctaaggtc agtagtttta cgatttaaat ggagggatga
      481 aaatggaaga agaaaaaatt aactatgctc tggaacagat tccagagaat caaaaacgtg
      541 gttgggtagc tatgttttca gttttagtag caataggtgt agatttatca tctgttattt
      601 taggcgctga gttggcacag agtatgccaa tgaaacaagc aatattgtca gtaattgttg
      661 gttcattttt ttctgcaatt ttgtatacta catgctcttt ggttggttca tctacaagtt
      721 tatctacatc tatgataaca aagtatgtat ttggagaagc tggagcaaaa atattttctc
      781 tagttatagg ggtttctcta ttaggttggt ttggagttca agtaggtttc tttgctcaaa
      841 atgcacagat aataataaaa gatatattta atttagatgt cagtatgcag attttaagcc
      901 taataggtgg tctcttgatg atgagtactg caatttatgg atataaggca atggagaagt
      961 tgagtgtgta ttcagtacca tttttattag ttcttatgat gctaactata ttcttagctt
     1021 ttagagcaaa tggaatttca gttgatgata atatgaaatc tactatgaca tttgcaggtg
     1081 gagtttctct gtcaatgagt ataataatag ttggtgcaat tgtatctcct gatataagtc
     1141 gttgggctaa aagtagaaga gactgtgctc tttcaagctt tttgggaata caatttggaa
     1201 atgcttttat gataatagtt tcgatagtat tagtaaaatg tatgggaact tcagatatta
     1261 tgagaatttt tattacatta ggaattgcta taccaggtat aatagtactt acattagcac
     1321 aatggactac aaatacaagt aatgtatatt cagcatcatt aagtatagct cttgtactta
     1381 agaaggctcc tgagaaagta ttaactatag tccttggtat tatagcaaca ttattggctg
     1441 tatttggaat atatgaaggt tttataggat ttttaaattt acttggaatt gtaattgcac
     1501 ctgttggtgg tgtatataca gcagaatatt acatagtaaa gcaagaactt aaaggctttg
     1561 ataaaggagt attatataaa ccaatagtta aacgttcaat agtgtcttgg ataattggta
     1621 tattaataac ttacctttca acatatggat ttataactct tactactata gcacctttag
     1681 atggttttat agcagggttt gtagtacaat ctattattgg aaaagtgctt tgttcaacaa
     1741 aaaataagca agaaatagac aaagcagtat aaagaaattt gtttataaag tataaaataa
     1801 attagaaata tgaggagaaa gtaacatgag atttttaaca gaagaaagtg tagataaaat
     1861 agcagttggt gcagcagtgc ttggaactgg aggtggaggt gacccatatg taggtaaatt
     1921 ggttgcaaaa caagccatta aaaagtatgg tcctgtaaaa gtaataagtt tagatgaact
     1981 tgatgatgat gctttggtag ttccagtatc tggtatgggt tctcctgtaa ttacaataga
     2041 aaaattactt tcagaagtag agttaactac ccctttagaa ataatggaga aattattaaa
     2101 tagaaaagtg gatgttataa ttcctataga aataggaggg ataaactcac ttatgcctat
     2161 agcagttgct gctaaaaaag gacttcctat cttagatgca gattctatgg gtagagcttt
     2221 ccctgaagct caaatggtaa ctttttatct tgaaggatat gaggcatctc ctgccgtaat
     2281 gtctgatgaa aaaggtaatt ctgccatcct ttatcctgtg gatggaattt ggtcagaaag
     2341 attagctaga actttaactg tagaaatggg aggaagttct tctattagtg actataattt
     2401 aagtggagct caagttaaaa aagctgctat aggtaatact cttacaatag ctgaaactat
     2461 aggagggttt ttacttgaaa ataaatctga ttcaaaaggt gctgttgaga atatactaaa
     2521 agaattgtgt ggatacaagt tatttgaagg aaaagtaatt gatattaaga gagagttgaa
     2581 aggtggattt actagaggac atgccttttt tgctgggatt aatgagtatg atggagagta
     2641 ttctatatta ttccaaaatg agaatttaat tgccaaaaaa ggtgatacac cactttgtat
     2701 tacaccagat ttaatagcag tattagattt agaaactgga tttccaataa ctacagagag
     2761 aataaaatat ggctctcgtg ttatggtagt agcttttcct tgtaatgaaa aatggagaac
     2821 agaaaaagga attgagacag ttggacctgg atactttgga tatgatgtgg aatataaaac
     2881 agtagaagaa ttacaaggaa aataaaagtt taggaggaaa ttttgatgta tcgtgtagga
     2941 attgacgttg gaggaacaaa tacagatgct tgtatactgg atggggaatt aaaagtaatt
     3001 cattcagtta aggtggcaac tacaaaagat gttgaaactg gtgtttacaa tgccttaaaa
     3061 aaagttatag atgaaagtaa gattgaccat tcattaataa aatatgctat gcttggtaca
     3121 actcattgta caaatgctat tgtagaaaga aaaagactta ataatgtggc tatgataaga
     3181 ataggaaagc cggccactac tgccattctt ccatttatag attggccaga agacttaaga
     3241 gaaaaaatag aattagattc aatattggta tctggtggat atgagtttga tggcagaaaa
     3301 ataaatgaac tttgtaaaga tgaagttgta gagttttgca atagaataaa aggcaaagtg
     3361 gaaagtgttg caataagtgg agtatttgct ccagtaaata aacaacaaga agaagaagtt
     3421 gcaaaatggg ttagagaaat tttaggggat attcctatat ctttatcaaa tgaaataggt
     3481 aatataggta tattagaaag agaaaatgga gctattttaa attctgcatt gtctcaagta
     3541 ggtaaagctg tatctttagg atttgaaaaa gcacttaaag acttaggtat agatgctcaa
     3601 atatatttca gtcaaaatga tggaacatta atgaatttag agtatacaat gaaataccca
     3661 atttttacaa ttggatgtgg aataacaaat tctataagag gagcttcctt cttatcaaaa
     3721 gtaaaaaatg caatagtatt agatgttggt ggaactacaa gcgacttggg tgtactatat
     3781 aatggattcc ctagagaatc atctattcca gttacaattg gaggagtaca tacaaacttt
     3841 agaatgccag atgttttaac tattggtctt gctggtggta catgtgtaaa aggcgaaaaa
     3901 gataatataa agataggtcc tgaaagtgtg ggatatagaa taactgaaga tgcaataata
     3961 tttggtggag acactctaac tttatcagat gttgttacaa aattagatat ggcgtttgaa
     4021 gatagaaaaa gcaatgttga aaacttagat aaagagtatt gtaatgaggt atataagaag
     4081 gttattttaa aattagaaga tgctgtagac caaatgaaga ctagtcaaga tgatgttgaa
     4141 ttggttttaa ctggtggagg aagtataatt gttcctgaaa aactaaaagg cataagcaat
     4201 gttataagac ctcctcatta tactgctgca aatgctattg gtgcagcttt aggacaaata
     4261 agtggagatg tagaaaaagt atacagttta gataaaatgt cgagagaaga tgccatagaa
     4321 gatgcaaaaa aagaggctgt aaataaagct ctaaaagctg gtgctaaaga agatactata
     4381 gaagtattaa atatagaaga tgttccactt gcataccttc ctggtaatgc acttcttata
     4441 aaagtaaaag ttgttggtga tttaatttaa agaataaata taagtatttc cagaattata
     4501 taaatatttc tggactcatt tttaaactta ttttatcaat aaaaacagca taacttttga
     4561 ctatattctt ataagtttcc gaacagccga tatataccta ttttttgagg tttatcggct
     4621 gtttgttatc ttttatcgca ttccaactat ttttcttacc gtatttgctg tacgaattgt
     4681 aatcttatca cttacatttg aactggcagt ctttgaccac caatttgtct ttttataatc
     4741 tttacgacta aaagaccaaa agatagcatt tttataatga tatacttttt catactcttc
     4801 tttaggattt ccaacctcat cataaaactc gtcataagat aagtcaggaa acataaaaat
     4861 aagattatca tatatttctt tgttgttatc tccccaccaa ttaggagcat tatttagtat
     4921 atcttttaac tcttcttgtg aaataataaa aactggtatt tccaattcaa actgtttttt
     4981 tatcattaat cttattgtat ttgagataac cttgctgtca tctacatcac ttaaaaagac
     5041 aacattacca ctattaaggt atgtagaaac ttctgaataa ccaagttcta caaagcttgc
     5101 ttttaattca gacataatta tcttgttctt accacttata ttgatacctc ttaataatgc
     5161 gatataactt ttcatataat aatttcacct ctaaacattc acatttttct atgtagtaca
     5221 aacttgaatt tgcatctttt ataattcttt caaaacttct tcatatgtaa tttttttaat
     5281 ataaaaaaat cggtgcttaa tttgtaccga tttttgtttt tcctagtaaa gaactcgttt
     5341 ttttgcttct gctatagctc tagcagcact ttttgcttgc attctttttt cttcttcttt
     5401 tttaaattca tttattgttt catttagatt cttatcatgt tcattttttt ctttatcttc
     5461 gttttctctg tatactaata tataatctat tattgattcg tttattattt gagatatact
     5521 tttattttca ttaattccta ttctcttaac ttccttaagt agagtctcat caatatgaac
     5581 cgttgtttgc tttgtatttt ttgccacctt aatcacctct taaaaaaaat tctaacatta
     5641 aaattttttt tagtcaataa attttaatat taaaattctt taaatgtttt atttgatttt
     5701 ctaaaatttt ctattgtatt tatcatctta ttttttatat tttcacctag tacagaagac
     5761 tttagtctag gattttcgat atggtcataa attggttcta aaaattcgac ttcgacagga
     5821 acagagttaa ttttaccaat aggttggtat ccttcataag tatcttttga attttttatt
     5881 actagtggaa caatagggca ttttgcttta tatgctatct ttaaagctcc acttctaaac
     5941 tccgaaacca atgaatttgg ttctttaatc catgttaaat ctccttctgg aaacactgcc
     6001 atactttgac ctgtaagtat attttgagag gcttgggcta tactctttat accctcacga
     6061 ttgttttttc tgtttacata tacacatctt agtaattttg cccattcttt aaatataggt
     6121 atatttctcc aaactggttc atctgcaatt acacatccaa ttggtctttc tacacttgct
     6181 gttagtatga agctgtcaag catactagaa tgatttacaa caaatagaag tggttctttt
     6241 ggtagtgttt ccttaccaat tatattaagc tctatgttca ctatatctaa agatttttta
     6301 gcttgttttt gcataaattc aaatttttcc tttaagctaa atttatcagg attcttttta
     6361 attttaataa gcctaggtat agaagatgta aaacctataa gttgatatgt agcaaatttt
     6421 aagtaattat tcataaaatt atctccttaa aataaaatta tttattactg taaagatttt
     6481 aacataaaat aaaatttaag tctattttaa ttcaattttg taacatatat tttaaataga
     6541 cagagattga gattttatat ttccaatttt agtaatcaga ttttatcaat aaattactat
     6601 tctattaatt taattaaata acctttaaat ttaattataa aaactgttgc agaaatttct
     6661 acaacagttt aaaaaattta ccttacaaaa acttatttta taacaagaga gtatattata
     6721 aggctagtac agcccatttt ttgcactgag aaattctttt gccatcatca ccttgttctt
     6781 tgtcatatgc aaattgatta agcatttcac atggaaatgt atcacataga ccacaatgtg
     6841 taaggttttt atcttcacaa caagatttta caagacattg ttcaccccaa aatggtttct
     6901 caatctctgt acaaccttta caattgactt tttccttgta tccacattca taacataaaa
     6961 ttccacatct tgattctatc attttaagtc actccttaaa tataaatttt atatgattgt
     7021 atatcaaaat ttatactttt cattgtaaaa atcggacaaa ttttttatat aggttgttgg
     7081 attaacacca caaatagatt taaaatcatt tataaaatga gattggtcgt aataaccaat
     7141 atcttgtgct aaagttgcaa agggtatttt attattttgt atttcttgta atacaaggtt
     7201 tatacgaagt aatctaaggt atgatttaac actcatacca agagaattat taaaaattct
     7261 atttaaatgt cgttcactat aacaactaat ttgtgaaatg tttttaacag acataataga
     7321 gttttgtttt ctagcatttt caagaattgg tatagtcata tctactatat ttgatttcaa
     7381 taagtatgat aagaataaca tatctaattg ttctactaat tcctttatag tacttgttct
     7441 ttcaaaaatg gaattaacct ctaagctaaa taatgtgtta aaatcttcaa gtgaaatttt
     7501 taaatctgta gattctcttt gagaaagacc tgtcaaataa tatactccac ctgggcgaaa
     7561 ctcaacgaat actctaaaaa gtacattttc tatatcattt tttacaatag tagtttttgt
     7621 tgtggctccc cagaatgcgc tttctatacc ttttttgtca aatttaaata tcatacatcc
     7681 actagcatca ggtattaatg taagattttc tttaatactt gtatctggaa tagatattgt
     7741 atagtgtgct atatactgtc ttaacaattt atgtggcaaa atatatgtat actgtttgca
     7801 ggtatttaaa atgttattga ttattttatt cataagtata tcctcctgat a
//
LOCUS       DAEPXW010000140         7803 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.144, whole genome shotgun sequence.
ACCESSION   DAEPXW010000140 DAEPXW010000000
VERSION     DAEPXW010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7803
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.144"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            469..1770
                     /locus_tag="KRM55_003366"
     CDS             469..1770
                     /locus_tag="KRM55_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1595557.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1846..2121
                     /locus_tag="KRM55_003367"
     CDS             1846..2121
                     /locus_tag="KRM55_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1595558.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3401..3631
                     /locus_tag="KRM55_003368"
     CDS             3401..3631
                     /locus_tag="KRM55_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1595559.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3624..4205
                     /locus_tag="KRM55_003369"
     CDS             3624..4205
                     /locus_tag="KRM55_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1595560.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSI"
     gene            complement(4780..5457)
                     /locus_tag="KRM55_003370"
     CDS             complement(4780..5457)
                     /locus_tag="KRM55_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1595561.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5646..7010)
                     /locus_tag="KRM55_003371"
     CDS             complement(5646..7010)
                     /locus_tag="KRM55_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1595562.1"
                     /translation="MKESNKKIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYVARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7138..7659
                     /locus_tag="KRM55_003372"
     CDS             7138..7659
                     /locus_tag="KRM55_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH1595563.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3047 a          873 c         1343 g         2540 t
ORIGIN      
        1 taatattgga tagtgaatta tagtggacga tatatcaata attggtagta aattatatta
       61 agtaagatat tactatcagg tagtgaatta tattgaacga tatattaata attggcagta
      121 aattatatta aataagatat taatatcgag taatgaatta tattgaacga tatatcaata
      181 attggcagta agttatatca aataagatat tactatcgag taatgaatta tattgaacaa
      241 tatattaata attggcagta agttatatca aataagatat tgctattatg tagtaaatta
      301 tataaaacaa tgtatcagaa taaatagtat attaataatt tgtagtatat catgacgaat
      361 aatacagtca taacaaatag tgagtcataa caaataatgt atttataatt gataatgtat
      421 ttaaaaatca aaatataaaa acttataagg aaagagagat taatttatat gggtaaatca
      481 aaagatgttg aaatagagaa gtctatttta ggcacaattc ttttagacaa taaattaagc
      541 tataagctag atgaattaaa tgaaaacatg tttatgaatg atatatgtct tgagatattt
      601 aaaattatga aagaacttaa aaaagaaaac atagtgattg atgtggccac tgtgaaatca
      661 aagatagata gaaaatctct agcaataaaa acgagtgatg tgactaatct aattacttgg
      721 ggtcagaatt ttggtcttga tggtcatatt aaaattttaa aagaaaattt agctagaaga
      781 agcataaatc aaaactgcca aaacctttta cacagcctaa accttggaga aaatatcgat
      841 acttgtattt acaaatttga aagtaatata aaggagattt tggacaagga tacttatgaa
      901 aatgatgatg taaatagtat agcagggaag gtgcttgatt ttttagaaaa caaaaaagat
      961 attggattta aatttggtat aaaattactt gataccacta taggaggtct ttttaaagga
     1021 gagctaacca caatagcagc taaatcgggg gttgggaaga ctgctttggc acttcaaata
     1081 atgttaaatt catttaagca aggtaaaaaa actttattta taagtagaga aatgaccagt
     1141 gagcaagtat ttatgagaaa tatatgcaga gtaactggtg taagtacaag gaatatgaaa
     1201 tctaaagaaa tagatgaaaa tgattggaaa cttattgtaa atgctatagg tgatttaagc
     1261 gaaaataact taatttatat caatgataag atagatacaa ttagtgcaat tagaaagagg
     1321 ataaggcagg taaagccaga tttattaata gtggattatg tgcaactcct tacatctcag
     1381 aaaagcatgg ataagagaga aagggaagta gctacttttt cgagagaact taaaaatatg
     1441 actttagatt ttaatatacc tgtaatccaa ttaagtcagt taaatgatga aatgaaagat
     1501 tcaagacctt atggagatag acctatgagg gatagcaaag ccatctacca cgatagcaac
     1561 aatgtggttt atatacatca attaaagggg agtgattatg aagaagcagt gagagatatt
     1621 ggagaaagtg aggaggcagt tagagcatca gaatacaggg gaattaagat ggttgattta
     1681 atagttgcga agtgtagaga tggacagact aggcataagc atttttgtta ctttggggat
     1741 aagttacatt ttcaagaact aaattattag gtcaataaag tagtaataac aagcttatta
     1801 aaagtcggga aatagcaaat agattataaa atatgaggtg aaaatatgtt ggaattaaga
     1861 aaaattatag aattacttga agaacacaag atagaagtaa gtattccaaa ggagttacat
     1921 aagtatagtt tattggaata ccttgaattg tgtcaacaaa gtgggggaac atatttttat
     1981 attaaaacac tggaaggggc tttaaaagag gctagaaatg agcttatgat taaattgttt
     2041 aatgggaaaa attatatgga attagcgagg atgtttgaaa tgagtgttat taatgtcagg
     2101 catattgtta gaaaaaaata gatatttttg gagaatacaa gtgtgatata cttctgaaat
     2161 agaagttatt atagttgaaa taaaattgtg gttaataaat taaagttgtg tataagttta
     2221 agattataga ggagtataag tgtgattaac aacatgattt tgtgaataaa attgaggata
     2281 tatatgagtt aaatgtgtga ttaataaggt aaggttgtgt ataagattat gagtatttaa
     2341 aaggaggggc tataattaat agtgtagagt tgtgtgtttg cttaagatta tataataatt
     2401 taatagatta aactatacta ataaggtaaa atcgtgtgtt tagttaaagc ttattataaa
     2461 atcttgatat gtgattaatg atgcaatatg tgaataaagt taagattata atagatttaa
     2521 cctgtgtcta atagaataaa attgtgaata aagttaagat tataataggt ttaatctgtg
     2581 actaatagag taagagtgta aatagagata aacttcaata tgagcttaac ctatgattaa
     2641 tagagtaaga gtgtaaatag agataaactt caatatgggt ttaacctatg attaatagag
     2701 taagaatgta aatagagata aacttcaata tgggcttaac ttgtggctaa tagagtaaga
     2761 gtgtaactaa agataaactt caatatgagc ttaacctatg attaatagag taagaatgta
     2821 aatagagata aacttcaata tgagtttaac ttgtggctaa tagagtaaga gtgtaaatag
     2881 agataaactt caatatgggt ttaacttgtg gctaatagaa taagaatgta aatagagata
     2941 aacttcaata tgagtttaac ttgtggctaa tagagtaaga gtgtaaatag agataaactt
     3001 caatatgggt ttaacctgtg gttaatagag tagggtgtaa ctaaagataa acttcaatat
     3061 gagtttaact tgtggctaat agaataagat tgtgaataaa gttatagttt tagatgggta
     3121 ttaacctgtt actaatagaa tatgattagg tgtaaaatta tagagctgta taagaaaata
     3181 ttatagatat attaaatatt agataataaa tatttatata gatacacaaa agaaaaggcg
     3241 atatgaagct aaacttaatg acttcatatc gttttttatt tgaaactcct ttgtatttag
     3301 agtgtgattt ttaatattga ggttttatgt gattaagtca cagataaaaa gtaagtatct
     3361 tgatataatt cttatagatt aataatatag ggaggttatt atgtctaata aaaaaaagaa
     3421 gtatgcaaat attttagcaa atgagtgcgt tgcttgtggt agctgtataa aagcatgtcc
     3481 aagaagtgct atctcagttc catgtggcat tagtgcaaaa attaatagag atttatgtgt
     3541 tggatgtggg atttgtgaaa agatatgtcc agcatctgta attgagatta taacaatatt
     3601 aaaagaggaa gaaggtaagt gtcatgaata ataaaaaaca ttggtatgac tatttatgga
     3661 ttttttcttc aatatatttg atattgggat ttgtaaatat tattttcgct tggattgggc
     3721 taatttgttt ctttgttcca ctagctattt ctattgttaa gggaaataaa gcttactgta
     3781 ataagtattg tggaagaggg caactgttta atttgcttgg aaataaattg aagctgtcaa
     3841 gaaatagaga tattcctaaa tttattagaa gtaagtggtt tagatatggg tttttgacat
     3901 tttttatggt aatgtttgcc aatatgcttt tttcaactta tttagtgttt gaaggaagta
     3961 gaaattttaa agaagtagtg actttgttgt ggactataaa aatgccttgg caatgggcgt
     4021 atcatggaac tttagtttca ccttgggtgg tacagtttgc atttggtttt tatagtgtta
     4081 tgcttacatc aactgttctt ggtttgatta ctatgatatt gtttaaacct cgttcatggt
     4141 gtgtttattg ccctatgggt actatgactc agatgatatg taaggcaaag agtaagtcta
     4201 tatagaaagg ctttatgtga tatttacagt tttgttagag atgagtagta ggtttgaata
     4261 tatatgacaa atatatgagt ataggggcat agatttagtt tgtgtaaggc aaactgattt
     4321 atgcttcttt tttatgtctt agattattgg ctaagtggaa acaatgaatt tagatattaa
     4381 gaattattca gttatttgaa gaaaatagaa taataattaa cattatatta atggatattc
     4441 attacatata agccagttaa tagcaagatt tatttaatat gaaataggtc aagtatttaa
     4501 actaaataag gtcatgacaa ttaatataag tatagatata aaaagattag aagttataac
     4561 ttataaaagg tattctatat aaatagtatg tggaaaatag tcaaattaac ttattagaaa
     4621 caaaaaatat acataaaaaa ataaatgtaa atatcaaata agatactata taaaaataga
     4681 tataagtatc ttttttatta ttgaaattat gaaaatatat ttgatttcac acaaaaaaga
     4741 gtgcctcatg aactaaaaag ttcattttga gacacacttt tacagtgtca aagaacgaag
     4801 tttatcctta tccaatactt ttataccacc acgagataaa gacacaatac cttctctagc
     4861 aaaatatttc aacattctcg atacaacttc tctggcacta cccatatact tagcaatttg
     4921 ctcatgagtc atatttatag tgctactgcc atttttagct atctcatcaa ttaaaaaaga
     4981 tgccaaacgc ttatcaaaac tcataaaaag aatttgttgc atagcccaca taacatcaga
     5041 aaaacgttcg gtagctaatt tatatgaaaa taactctgca tgaatatttt ctgtagataa
     5101 ttttgcaaaa acagaggaac taatctgtat aatatcgcag tccgtttcag catctacata
     5161 gacatcaaaa gttattgttt ttagaataca ggaagctgat aaaatacata catctccatc
     5221 atcaagtcgg aacagtgtaa cctctcgacc ttcatctgaa agtatgtatg tacgtactgt
     5281 tccagacttt ataatcaaaa taccaataca gtcactatca ccacaatgta ctggattccc
     5341 ttttttgtaa tgcgaggtat ttgctgaaga aattaataat tctttttgta agtcagtaag
     5401 tttatcccaa aaaggcaagc tatgtgtaag tatatcgatt tcattttgtg aaatcataca
     5461 atatctcctt tcttaaattg ttataatccc atgatacaag tgaatagata aattgacaag
     5521 tagtttgtta ataggattat ttagtcagat agtaatagta tgatttatgt agaaaaaata
     5581 tgataatatg tattcttgct attaatgaga aagtaatatg ttttgatgat agtaggtttg
     5641 tataactaat gcataccgtt tatttttaaa agattaagtt ccttatgtaa tcttatagac
     5701 ataaaaccag caattatagc agccatcaaa tcagctattg gttgtgcata taagatacca
     5761 tttaacccat agaatacagg aataatcaaa attataggga taaaacagac accttgtcta
     5821 cacataccta aaaatccacc ttcctttgct tttcctagtg cgaggaataa tgtagaatac
     5881 actgtataga atccaaatag cataaatgaa aacccatttg ccctaagagc tttactacca
     5941 ttttctatta ataaaatgtc accacttgta aattgtgaaa ttatagattt tgggaagagt
     6001 atcaatataa gaccaagcac tacacaaaat actgtagtcc ataatatgga agtttttatt
     6061 gctatatgta atctatcgta gttctttgaa ccaaaattat aaccagcaat tggttggaaa
     6121 ccttttataa aaccaaatac aacaagacta cctaaagacg ttattcgtgt tacagcaccc
     6181 attccagcta tcacagaatc accatacttt gtagcctcca tattagttaa tgtaatggca
     6241 agactagtca ataattgaaa tattaaggta ggtatgccaa tttttaggat ttctgaaaaa
     6301 atttcttttg aaaaacagca ttcgttaatt ctaaaactaa atatactttt cttgcttaaa
     6361 atatatccta cataaacaag tgttgaagca atctgtgaga tagctgttgc aatagaagca
     6421 ccccttaccc ccagaccaaa agtataaatg aatatcgggt ctaaaatcat attaagcaaa
     6481 gcacctaata acatagcaca catagttgtt ttagcagctc cttcacttgt gacaatatta
     6541 gtcatagtga cattgaatat attaaaaata gatgatacga cataaatgct agcataagat
     6601 attgcataag gcataatact ttttgtagct cctaataatt ttaaaattgg attgagaaaa
     6661 atcataatca caataataac taatgtaccc actataatac tactgtaaat agatgtactt
     6721 accacttttc ctgctttttc attatcacca tggcctaaaa gtctggcaac atatgaagca
     6781 gctccatttc caaacaataa tcctaatccc acaacaagct gacctaatgg aaatgcaacg
     6841 gatatagctc ccatttgact tgttccaagt ccacccacaa agtatgcatc aaccaaattg
     6901 tataatgcag ttatcatcat acctatcatg gtaggtaatc ccatagataa caatgctttt
     6961 gagattgggg cagaccctaa taattcaatt tttttgttac tttctttcat acttaacact
     7021 cctcttctat tgacattaag tctaaattat aatactataa attatagtaa gtatggaaaa
     7081 tagtactata atttatagta tttgtcaata gtaagaaaac taaaggagat gatttttatg
     7141 gctacaatag atttaattgt attgggaata gtaaagcaac aacccaagag tgcttatgat
     7201 attcaaaagg cagtggaata caggaatata tcacgttggg ttaaaataag tacaccatca
     7261 atttataaaa aagtaattca attagaacaa aagggatata ttgaaagtaa aactgtgaag
     7321 aatggaaaaa tgccagaaaa agcagtttat tcattaactg aattaggtga gacacatttt
     7381 ttagatttaa tgtttgatac atctagcaaa ccaataaata ttcttttaga ttttaatgct
     7441 gttatagtaa atttaaatag ccttacacca gaaaaacaga aattatgtct caataatatt
     7501 gaagagaatg ttcaagagtt aaagaaaact attgaggaaa atataagtat aaagacagaa
     7561 gtaccagaga cagcaaaagc agtgttggag caacagttgg tgctagcaca agcattggaa
     7621 acctggataa attctttaaa agataatatg gggaattagg attagagaag ctaacttaat
     7681 aatcattaaa caaaaaccag catatttaat aatgagatat tagaaaaaat aaaacaaatg
     7741 atataaactg aaaagtatat ttaaaataaa gctcacttaa ttgagggaga atgttaaact
     7801 ttt
//
LOCUS       DAEPXW010000141         7672 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.145, whole genome shotgun sequence.
ACCESSION   DAEPXW010000141 DAEPXW010000000
VERSION     DAEPXW010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7672
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.145"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            107..2335
                     /locus_tag="KRM55_003373"
     CDS             107..2335
                     /locus_tag="KRM55_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBH1595564.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
     gene            complement(2573..2872)
                     /locus_tag="KRM55_003374"
     CDS             complement(2573..2872)
                     /locus_tag="KRM55_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBH1595565.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            3078..6119
                     /locus_tag="KRM55_003375"
     CDS             3078..6119
                     /locus_tag="KRM55_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBH1595566.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKIDDNNISNSVKEAWKKRNGKDYYLVDEKYTSQSYMFGSVKATLALSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSSFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            complement(6280..7554)
                     /locus_tag="KRM55_003376"
     CDS             complement(6280..7554)
                     /locus_tag="KRM55_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1595567.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSINDK"
BASE COUNT         2833 a         1077 c         1099 g         2663 t
ORIGIN      
        1 tattaaaatt aagacaaaat tttaacttta ctatttgtgt aaaaagtaat ataatttaaa
       61 attgattata aatctaactt ttttctttat caaaatattt taggaggtga gacatttgaa
      121 aaaaactaat agtttaaaag aaattttaaa ctggaataat atcaagaatt taagaccttc
      181 aaagggttta aaaaatatat tagaaatttt taaaagtgac ctaaaagata tacgtggcaa
      241 ttatgccgta cttgtaatag ttttaggtct tgctttttta ccatctctgt atgcttggtt
      301 caatataaag gcatcttggg acccttatgg aagcactgct aatatgcttg tagcagtaac
      361 aaatgaagat aaaggaaatg aaatagcagg acaaaagatt aatgtaggag accaattaat
      421 tgaacaactc aaagataaca agagtttagg ttggcagttt gtagatgaaa aaactgctct
      481 tgaaggtgtt aaaaaaggta cttattatgc atcacttaag attccaaaaa attttacgaa
      541 agatttgaca tctttaatta cagatgatgt taaaaaaggg gaaattatct atactgttaa
      601 tgaaaaaata aatgcagttg caccaaagat tacagataaa ggtgcttcta caatacaact
      661 acaggttaat cagactatag taaaaacagt tagtgaaatc gttcttggta tatcaaacgg
      721 agttggtgca ggaattgaac acagtcttcc aaaattgaca aaagttgaaa attcccttat
      781 tgaccttcaa aagagatttg accatataaa taagactgtt gatttagctt ctgatgctac
      841 ttcaaaatta tctgatacag ttaaagatat taaatctgat ttacctacaa ttaaaaagac
      901 tctgaatgat acaaaactgt tatcaagtga cttaaaaaaa ttcttagagg atacaaatga
      961 taatttagac gaactttctc ctcttattaa gtctgactta aatttaatgg ttgacctttc
     1021 atcttctgct tcttctctta cattaaattt aattgatgca gtaaatagtg gcagtgaaga
     1081 tgtacctaag ttgatagata atttatcaga aaaactttct aatttgcaat ctttaaatga
     1141 tactttggtg gattttttaa ctaaattaaa ccaacttaca tcaaataata gattggatga
     1201 tgtcatagat aatcttgaag actctagcaa taaaatagat tcatctatat caacattaaa
     1261 tgatattaaa aacaaagtta tatctggaca acaaccatct ataagtgctt tgaataatgt
     1321 tttaagtcta tcaaatggta ttggaagaat taatttaaat attttaaata attttgactc
     1381 aaaaatatca aaacctataa atagtatatt tgcaaacagt ataaaagtag caaatgatat
     1441 aattactgtt ttagataagg cagaagcaaa acttccaaag gttgaagaaa tacttactac
     1501 ttctctaaaa ctttcaggaa atgcacagga aagtatatca ttgataagag aaagacttcc
     1561 tttagcaaaa ggaatgttgg atgatttgat tgatacttta agcaaaatta gtaatggtga
     1621 agatatgaaa aaattagtca gcttgcttga aagtgatata ttgacaaagt ctaatttctt
     1681 aaaagaacct gttgaggtga aaacagagaa attatatcca attgaaaatt atggttctgc
     1741 aatgacacca ttttatagtg ttctttctac atgggttggt atattactta tttcagcact
     1801 attgtctaca tctgtacatg gaaactataa accttatgaa atttactttg gaagaggcct
     1861 tactttttta agtatagctc ttgtccaagg ttttataata ggaactggag atatattatt
     1921 gttaggagta acagcaaaac atccaatttt attaatagtt ctgcttatgt ttactagtat
     1981 ggtatttaac tttatagtgt attctttagt ttctgtattt ggaaatgtag gaaaagcaat
     2041 tgcaatagta ctattagtcg ttcagattgg ttcttctggt ggtacattcc ctatacaagt
     2101 tacacctaca ttcttccaaa gaataaaccc tataatgcca tttacctatg caataggtgc
     2161 tacaagggaa gcagttggtg gtatatatgc tccaaatcta actaaagata tactagttct
     2221 attactattt atgattctgt ctatttgttt aaatgtactt ctaaaaggac ctataaatag
     2281 agttataaaa ccatttaatg ataaattcgg cgatagtaat ttaactggtc attaaaaaat
     2341 taattctgtc tttaaatata tttttttaat aatattctaa gttcatatta aaaggtagta
     2401 gctaaaaagc tactaccttt ttccaactta aaaactaata tttactacaa aaactgtcat
     2461 agaaaaaaac gaaaaaattc gttctttcct aaatttatct tataaatatt tagatatatt
     2521 cctacttaat aagcagagct atacatagta tttaatgtat aacttacatt atttaactca
     2581 tataatcaat tattcctgaa tttaaattat ataaatgctc aaaaccttct tcagctaaca
     2641 aattacatgc agtaacactt ctatgaccac ttctgcaata aactactact ttcttatctt
     2701 tataatcgta aatttcatct atattattga ttaactcttg taaagatata tttatagcat
     2761 tttctatttt atattcctta aattcatctt tagttcttac atctaataat aaaacatcct
     2821 tttcattttt catcatttct ttaagttgct ttttatttat attcttatac attgtctaaa
     2881 attcctccat tttatttata tattacctat accctttatt ctttatacaa caacaaatat
     2941 tatttttata tttttctctg ttatataaaa agctatactt ataaaagctt tttttattga
     3001 taataatctg ttgattaaaa taattaagaa tgttatgcta attataaatt attaaaaagg
     3061 gaaagaggta atgtaatatg tttaagcaaa ggctctctaa attattatct agtacattag
     3121 tattgagtat gttatttact gctgctccaa atattacttt tgctgataat acaaaagata
     3181 attccgaaaa atatcaaagt tctgatatag aattacatga ttatagtaaa aacgcggaat
     3241 cttacacaaa aactaaagct cttgctaaag agaaaatcca aactttgcta tcaaagtatg
     3301 gtgctgtaag tgctcaatat gctttgattg ataatggcaa aattgagatt tctggtaatg
     3361 gtggagttta cagcaaacag gataacaaaa acttaaataa ggataatatg tatagtatcg
     3421 catctatcag taaaatgttt actacaacag ctgttatgaa gttggttgat gatggaaaat
     3481 taaatttaga tactcctgtt gtaaagtata tacctgaatt taaaatggct gatgatagat
     3541 acaaggaaat cactccaaga atgttattaa atcattcatc agggttgatg ggaagtagtt
     3601 ttaaaaacac tattttatta gcagacaatg attcttatgg tcatgataat ttcttaaaag
     3661 aattacaaaa acaaagatta aaagctaaac caggagcttt ttctgtttat tgtaatgatg
     3721 gatttacttt agctgaaatt ttagtagaaa gagtatctgg tatgtcattt actaattttc
     3781 ttgataaata cataaataat ccacttaact tacaaaatac aaaaactcca gaaaatagtt
     3841 ttgatagttc aaaactagca aaagcatacg taccttattg ggaagatgca gttccgcaag
     3901 ataaccttaa tgctataggt gcaggtggtt tatattcaag tgcagaaaat ctatgtacat
     3961 ttgcacaaac atttatgaaa aattcaaatg gtattctttc tcctgcttca gtaaaagcta
     4021 tggaaaacaa agaatattta aatggtctat ggcctgaagg agaagattct atacttggat
     4081 atggtttagg ttgggattgt gtcaacactt atccatttaa tcagtataat ttaaaagctc
     4141 ttacaaaagg tggagactct ttattattcc acagtaatct tatagttctt ccagatgaaa
     4201 atatggcagt tgcagttctt tcttctggtg gaagtagtca acttaacgaa ataattggac
     4261 aagaaatctt actatctgca ttaaaagaaa aaggtaaaat taaagaaata aaacctgata
     4321 aaacatttag taaaccacaa caagttaaaa tgcctagctc tctaaaagaa aatagtggtc
     4381 tttatgcttc ttcaaatatg ataaaagtag atgttaatga taatggtact ttaacagtat
     4441 cttctcctta tatagaaaat ggacctgaag ataaatacgt atacataggt caagatagat
     4501 ttgtatctga aaaaggtaac agctgtctaa aatttgtaaa agaaaaaaac aatatcacat
     4561 atttaaatat gagctcttat gatgatgtcc ctggattagg tcagacagca agtttatact
     4621 atgtagctca aaagatagat gacaacaata tatcaaatag tgtaaaagaa gcatggaaaa
     4681 aaagaaatgg taaagattac tatctagtag atgaaaaata tacttctcaa agctatatgt
     4741 ttggttctgt gaaggcaact cttgctcttt ctgatgaaac tccaggttat atagttaaca
     4801 ctaaaataat ggatgagaat aactcaaatg cttttataga aatacctggt gtaataggtc
     4861 gtgatttatc cgacattaaa cttcataaag aaaatggtac agagtattta tcttttggaa
     4921 cactaacgta tgttagtgaa gattctataa ctaatttgcc agcagaaaaa tcttttactt
     4981 gtgaactaga atccaatggt tatgcaaaat ggtataagat tggtgacgat atcgcaaata
     5041 aaaaaataga agttaatctt cctcaaaatt catcttttgc tgtttatgat gataaaggtg
     5101 ttcctgtaaa ctattcttta gttacaaaga acaatagagt tagattgcca aaaggaggcg
     5161 taattgtttt cttaggaagt ccaaatgcta gatttgaggt tacatatcaa gatgaagtaa
     5221 atgcaagtgc acttacagga actgatagat atgaaacttc tattaagata agtcaagcag
     5281 gttgggaaaa tgctgaaaat gcagttttaa taaacgattc agcaattgca gatgctttgg
     5341 ctgcaacacc atttgcatac aagaaaaacg ctcctatatt attgactgga agctctcaaa
     5401 taaatgaaaa aactttggct gaattaaaga gattaaaagt taaaaatgta tatgtagttg
     5461 gtggagaagc ttctataaat gaaaaatctt tagatactat aaaatcaaac aatatctctg
     5521 tatctagaat ttcaggaagt gatagatatc aaacttctat gaacattgct aaagaattga
     5581 acaatattag caatatatca aagatttcag tagttaatgg cgaaaaagga ttagccgatg
     5641 cagtaagcat tggagctgta tcagctcaaa atgatatgcc tataatactt actaatgaaa
     5701 atagtaatat aactgaaata aataacttat ttaaaaacaa aaagattgat aaatcttatg
     5761 taatcggtgg agaatataca gtttctaaaa atatagaaag taaacttcaa aatccacaga
     5821 gaatatcagg tagcactaga aatgaaacta atgcaaaagt aataaaagaa ttttacaagg
     5881 attctaagat agacaattta tatgttgcta aaaatggaat gaataaacaa gatgatttaa
     5941 tagacggatt atctgttgga gttttggctg gaaaaactaa atctcctgta atgctagtag
     6001 gaaactcact agattataat caaaaagaac tatttaaaac tatgagattt aaatctgtaa
     6061 cacaaattgg tggaaatgga aatgaaaact catttaagca aataaaagaa atagcttaac
     6121 ataactaaaa aaggctgtat tcaagtaata ttaattgaat atagcctttt tttatttaag
     6181 ttataagttt tatatgtgta aaaattaaat ttaaatatta aatgataagt ttattaagat
     6241 atagataagt ctaaaacttt gcctttttta agttagtttc tatttatcat taatacttaa
     6301 caatttatct aaatatactg actttaattg tttactggct aaaatctttt tagctggttc
     6361 aagctttaat atagctgaca gtatagctcc catagctcta tgactagcca gagcattatt
     6421 atcaaaaatt aaattttgta actgcccttt ttcaattgcc atgagaactg ctctatgtac
     6481 tgaatttgct ggagttatta ttttttcatc tctctttaat aacataatgc tatttttatg
     6541 gcaatttcta acacaaactc cacaacctag acatctatcc tcatcaattt ttatatattc
     6601 tttaccatct tccttaacct tgcttatcgc atctattgga catgcagtta tacatttacc
     6661 acactttaca caattttcat ggtttatatt tggtataaaa cttgttgtct gtactggatg
     6721 aagatttcca aatcttttag ctgctaccat tgcttcacag caacatccac agcaattaca
     6781 tataaacgta acccctttcc taacattttc tccacattga actaagttat gttcatatgc
     6841 ttgatgaagt agttctttac attctatttt atccacacgt cttgcaaatt tattatttat
     6901 taaagaattt gctacattgt caaacgtcat acatatatcc atgggagcat cacaagcttt
     6961 tccaacatgt tgcattctat gtctacagta acacatactt atacctatat gagttgattc
     7021 atcaattata tgagtagccc tttcataatc taaaatacta acctcattat cattagttaa
     7081 aacttcctct tgaacgtata ctcttccaag cttcgtttct gttgaataaa ataaatcttt
     7141 gataaaatct tcttctacat tcatatattg atagtaaagc tctgccaaaa gtttttggtc
     7201 tatatcgtgt ctcgttctca tcatggcaaa ctcaaaaaaa ccagccattg gaggaggcat
     7261 tatatatttc ttccctttat tatcttctat atctagtatc agagccttac tagcaagttt
     7321 atccaatact ctatatgctt cactttcact tacactccaa attttagctg ctgtttttac
     7381 tctgaaaggc tttattggaa gctgagcaac taacttcgcc tcttgttctg tatatagtac
     7441 atttagtatt ttgtataatg tatcagatgg tggagcacct tgtggaaact tgtttattct
     7501 ttcctctaaa cttttataca tattcttcgc agttatatga gaaatagtaa tcaccttctt
     7561 tttcttttgt tttccaataa aatcaaatat tctttcttat tatatattct cttactttat
     7621 ataataccaa ttctttctaa atagttaaat acctctagta atttattatt ag
//
LOCUS       DAEPXW010000142         7664 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.146, whole genome shotgun sequence.
ACCESSION   DAEPXW010000142 DAEPXW010000000
VERSION     DAEPXW010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.146"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(242..2521)
                     /locus_tag="KRM55_003377"
     CDS             complement(242..2521)
                     /locus_tag="KRM55_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1595568.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEVEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2792..4246)
                     /locus_tag="KRM55_003378"
     CDS             complement(2792..4246)
                     /locus_tag="KRM55_003378"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBH1595569.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVNTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4410..5279
                     /locus_tag="KRM55_003379"
     CDS             4410..5279
                     /locus_tag="KRM55_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595570.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDANSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNTLFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5492..7564)
                     /locus_tag="KRM55_003380"
     CDS             complement(5492..7564)
                     /locus_tag="KRM55_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1595571.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
BASE COUNT         2595 a         1279 c          817 g         2973 t
ORIGIN      
        1 tatagaaatt actattatta ctatctaaag tattttgcta taatcccata tactcttacc
       61 tcaaaaacat tcaaatagaa aaaatactac ataattaata aactttgccc aataattcct
      121 aaaataatat cctaacaatg atttatgttt ttataatagt atatttttac ataaaaaagt
      181 gaacattgat taacaaagtt cactttttta taaattttta tgttataatt cacaatttta
      241 tttaatttgt ttcttttcta tttaaactat atctatctaa tattaatttt tcatattctt
      301 ctattggcat tggtctagca aataaaaatc cttgggccat atcacaacct ataaacctta
      361 aaaactctgc ttgctctaca gtttcaacac cttctgaaac aacttttata tcaagttgct
      421 ttgccatttg aacaatactt gaaactacaa tttgactctt ttttgcattt cccactgtta
      481 taaagaattg cctatctaat ttcaatacat caattggcat atctttaagc atatttaaag
      541 aagaataacc agaaccaaaa tcatccatag aaattttaaa tccaacagat ttcaaagttt
      601 gcattatttt aaataatatt tttgtattgt caaatattgc actttctgtc aattcaatct
      661 caattaaatt tggttcaact tcatattctt ttgttattct ttcaagctca gaaataaagc
      721 ctggattctc aagatgtact cttgataagt ttattgatat aggaaatgtg gggaaatttt
      781 cattttccca acgtttaaaa tttttacaaa cttgggtaaa tacaaacata tccaattctg
      841 ttataaaacc atttttctca aaaataggaa taaatacacc tggacttatt agaccttttt
      901 taggatgttg ccaacgtaca agtgcttcag cacctacaat tttagtagtt gataaatcaa
      961 ccttaggctg taaataaact ttaaattgtt cattttttaa agcatcatgc atttcttgtt
     1021 caatatcacg ttcttctatg agagtttctt ttaaattttc agcataaatc tcataaactt
     1081 ttaaatattt tctttttact gtagtttttg caatcatagc tttgtcaaga caggtagaaa
     1141 tatttgtttc tccctcttca acaaaatata cacctatgga tggaattaaa ttgagttcta
     1201 ctcccaaact tgtttttatc attgacaatt ttttacgtat aagttcacat atttctataa
     1261 ttgactctct attatttttc ttttcaaata ttatagcaaa attgtcattt gaaattcttg
     1321 aaaatacaga ttgctcttta aatatattct taattatctc tgctatttcc tttaatactc
     1381 tatctccttc ttcataccca aacctatcat ttactagctt aaacttatct atatcaaaat
     1441 aaattaaaac tagattcttt ttctcatgag aggataaaaa ttttccccct tcaagattaa
     1501 atttatttga attgccaata cctgtaacgt tatctttaaa agcaaattct tccaattttt
     1561 ccttactctt tttatgtata aatagtatat aaattgttaa tgccgtaaag attataatca
     1621 agactacaca tgctgataat gtaagtttta taatagcata tgatttctca gatatagcag
     1681 ttttaggaac ttcagaaaaa agataccaat cattgattcc tattggggca taacttaaat
     1741 aatatccttt tccaaacata ctataactta atgaacctga tttaaagttt tttatatttg
     1801 acttcatatt attgatacta gattttgata ttgaatcact tctgccaatg taagaaaata
     1861 aattttcttt agtagagttg gcgtttttac tgcttggatt taaaacaatg tcaccattac
     1921 ttctagttat ataagaatat ccttttccat taaatgtagg tacagaaagt attttttcat
     1981 acaacttcgt actatgtgtg gcaaatataa ctcctttaac ctcattatct ttataaattg
     2041 gtacagaata cacattaata ttactattgg tatttttatc atcttctatt acatctttta
     2101 attttcctgt tataaccact tctccttgca ttgattttaa gaaataatct cttttagaaa
     2161 agtcttctat ataaccatct gtagtgtatg ctgtaccatt tggtaaaata actcccattc
     2221 ttttaaatga actattaata gcttgtcttt ttagtataga aaggatatta tctacttcaa
     2281 aagactcttc tccttcaata aatattgaaa ttgactctag taactttata tctccattaa
     2341 tttgtttttt taacacattg acgctttgat ttgctatttc tgaaagatat tgattcgttt
     2401 cttcacctaa tgtcttattc aaccttgaac cataaatcaa acaggaaatt gtaattacta
     2461 agatacttat gacagcaatt atggacaaac catacctatt attttttgca tcacttaaca
     2521 ttatgcttcc tgcctttctc gaatctatgt atgtataatc attatcttat gacaattatt
     2581 gtaaacattt tataataata cttatttttc catatttact gtaattatac aaaattataa
     2641 actttattac aacaataaat taattaatat agatattagt gtttatatta ttgcattatc
     2701 tattttacaa ttatttacat ataaaaaaat gtaatatcaa agtgaagctt gatattacat
     2761 ttttgttctt gtattttgtt taatttttat gctacatctt acttaaacac tcatttgcaa
     2821 cttctttatc atcaaaatga tgcttaactt tacctataat ttgataagtt tcatgtccct
     2881 tacctgttat aattacaaca tcatcctttt ttgccatact tatagcttct gctatagctt
     2941 gttctctatc aacaacaaca tggtaatttt cttttttctt gtcaattcct tcaagtatat
     3001 cttttattat tgcctctggt tcttcagttc ttggattatc agaagttata atacataaat
     3061 cagaatattt ttgtccaatt gctcccatca aaggtctctt ttcagtatct ctatctccac
     3121 cacacccaaa cacagaaatt atttttcctt ctgcaaattg ttgagttgtc tttagtacat
     3181 tttcaagtgc gtcaggagta tgagcatagt ctacaattac gcttatacct ttatcatttg
     3241 gaactgtttc aaaccttcct gatactccat tagaaagtct aaggccttct ttatatattg
     3301 gtttaggtat gccaagtaca tagcaagcag ctataactgc taaagtatta tatactgtaa
     3361 acattcctgg aactggtata aatattactt cttcatatga aggtgttatt aatctataag
     3421 atactccatc cgaatctgat tttatatctc tagccataaa atcagcctta gtattaacac
     3481 cataagtgta acaaggtaca tttatacctt ttatattttc atatatcttt tttccacctt
     3541 catcatctat gtttattata tttgccatag tagtcttaaa aaataatttt tcttttgctt
     3601 ttctataatc ctctaaatct ttatgaaaat ctaaatggtc tggtgttaaa tttgtaaata
     3661 tgcctagttt aaagtctgtt tcatcaactc tatttaatgc caatgaatgt gatgaaactt
     3721 ccatcgcaca gtagtcacat ccattatcca acatattatt aaaatgatat tgtaaatcta
     3781 tactttctgg agttgttgaa ttggaaacaa tgtctttttc tccatcaaaa atttttatag
     3841 ttcctataag tccaacttta ttcttattta aagttaatat ctcatttagt atagtagtta
     3901 tactagtttt tccattagta cctgtaactc ctataacgtt aaatttttga gatggatgat
     3961 tgtaaaaatt atcagctact tttgccatat cttttcttgt atcttttacc tttataaatg
     4021 tacatccttt tatttctaca tcttcttcaa caagaaatgc acttgctccc ttttctatgg
     4081 catcttttat atacttatga ccatctgaca caaatccttt tatacatata aataatgtac
     4141 cttttgtaac ctttcttgaa tcatattgta cattattaat atctatattt aattcaccct
     4201 tgacattgat tatatccaac ccctgtataa tatcatttaa tttcataaat gctttcctcc
     4261 ctttaaactc tttctgctaa aattacacta catataatat tatattaaga attttttact
     4321 atgtgaatgg ttaaaaatgc ttgaaacatt gcaaaaaatg ctctataatt ttctataata
     4381 taactgagga aaggtcttct ataaaaacta tggataataa aatcgggtac ttaaacgata
     4441 actttaaaat atttaatatt agagataaaa aagatataca atttgaatac cataatcatg
     4501 attttaataa gataattata tttataaatg gaaatgtaac ttattttgtt gatggtattc
     4561 cctataaact aaagccttgg gatatactct ttatcagcaa taatgaaata cataaaccag
     4621 ttatagattc aaatgtcttt tatgagagaa ttgcaatatg gattagccca gaatttatga
     4681 aaaaaaatag tgatgctaat agtgacttag aaaaatgttt taaaatagct acagagaata
     4741 aatgcaatag attgcgttta aatatacatg atattgaatc tattaagagt tttattgagc
     4801 aaataaatat ttccgaatcc aatactgaat ttggaaatga aatattgaga aatacattat
     4861 ttatacaact tatgatattc ttaaacagaa ttttcctaaa aaatgaaaat atggaatcaa
     4921 cagaagacgt tttttatgat gaaactatta agaaagtatt aaactatata aattcaaata
     4981 tagatgataa gctttcaata gatagcatat cgtctgaatt ttttataagt aagtattatc
     5041 ttatgagaaa atttaaatct catactggaa cgtctataca caattatata gttcaaaaaa
     5101 gattaatttt ggcaaaatca ctaataacca atggtcacct tatgagtgaa gtttgtaata
     5161 aatgtggatt caacgattat tctagttttg taagggcatt taaaaaaaac tacggtgtat
     5221 ctcctaaaaa ttatataaac aataaaaatc ctttggatat tactctttta gatgaataga
     5281 taatttatgt aaattttatt ttaataaaac ttgaagtatt agtgtattta tcttactaat
     5341 acctcaagtt ttttaatgtt ttaaaatata tcaaaatata atgatatata tttctattac
     5401 ttaaaatata tattaaataa attgcatgtt aactgaacct atttatatat ttattaaatc
     5461 tcacataact tttagttaca ctatcatata gctatcctat tttttcaata tcatctctta
     5521 atatacttac tctattctcc tcttttgctg tggttactcc ttttttaatg cttaatttct
     5581 gattttgttc taaattcgta aatactacag gacttattgt tgatagacca tttttttcaa
     5641 tatattctaa gtccatttta actaattttt ctcccgcttt tacttcatct cctacattca
     5701 caaatacttc aaatccattt ccttctaaat ttacagtttc tatccctaaa tgtataagta
     5761 tttctactcc acttttttgg gattttatta ttattgcatg cttagttgga aatataactc
     5821 caatagttcc atcaactggt gaataaatca atccatcact agatttaatt gcaaatccat
     5881 cccccatcag tttacttgaa aatacagaat ctggcacttc ttctatatct aatatctctc
     5941 catttgttaa tgaatcaatc ttttctacta aagcattttc catatttgca acttccatat
     6001 tttttttcac tttattttta tcaacatttt tagtaacagt actttcaacc tttgtttttc
     6061 cctctattat atcttttata tcagacttta ttgaatccga ttttggtcca aatatagctt
     6121 gaacattgtt gccaataacc ataacacctg ctgctccaag tgatttcaat ttttctttat
     6181 ctactttatt tatatcattt acaaccaatc taagtcttgt tatacacgca tctaggctct
     6241 ttaaattgtc tttatttcct aaagcaatca aaatctctga tgctaattca ttcttagaca
     6301 tttcaatgac ttcagcgtta gtttctgact catcttctct tcctggtgtc tttaaattaa
     6361 attttcttat cataaatcta aatacactat agtataatac tgcaaaacca atacctacca
     6421 agatagccaa gtaccatgga gttctattag gaagaacacc aaataataag aaatctatta
     6481 atcctcctga aaatgtgaat ccaattttaa ctcctaataa ttgcataatt gcgtatgata
     6541 aacctgaaaa taaacaatgt attgcaaata atactggtgc aacaaataaa aacgcaaact
     6601 ctattggctc ggttattcct gttaaaaaag aggttaatgc tgctgatgcc attatacctg
     6661 ctacaaattt tttcttttct ggctttgctt catgcaccat agcaagagct gctgctggaa
     6721 gaccaaacat cataaatgga aatgcacctg tcataaaagt acctgctgtg aaatttactc
     6781 catctttaag ttgagcaaag aatatctttt ggtcacccat tacaagctca ccagctttat
     6841 ttacatattc tccaaattga taccaaaatg gattatggaa aacatgatgc aaaccaaatg
     6901 gtattaatag tctttccaaa gaaccttcca taaatgctgc tagtgtttga tttgcttcta
     6961 taacattttt tgagaaacta agtaatccct cttgtattgg aggccaaata aaagacaata
     7021 taattcctat tgctatagca actaatgaag taacgattgg tacaaatctt ttacctgcaa
     7081 aaaaacctag atactgaggt aattcaattt tataaaactt tttataaaga taagcagcca
     7141 ctatccctat aataatgcca ccaaataccc ctgtttgaat tgttggtatt ccaacaatat
     7201 ttgcatacat agaattgtct accatatctt ctgtaacacc tgccataaca cccatagatg
     7261 tattgagaat taaaaaacct actatggctg ccaatgctgc aacaccttct ccttcagtta
     7321 aaccaacagc taccccaact gcaaatataa gtggtaagtt attaaatata atttgacctg
     7381 aactttccat tatacttatt ataagttgaa atgtaggatt cgccaaagct ggaaaatgag
     7441 ccaacaatgc gtctcctgct aaagcattac tcacgccaag taatatacct gctgcaggaa
     7501 gtaatgcaac tggtagcatt agagattttc ctactttttg taaaacacca aatacttttt
     7561 tcatttactt ttctctcctt attattttat atttttttaa ataaaaaaga cttaagttta
     7621 taaaaagtta cattagtata cttaattcta aaattaaact tatg
//
LOCUS       DAEPXW010000143         7483 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.147, whole genome shotgun sequence.
ACCESSION   DAEPXW010000143 DAEPXW010000000
VERSION     DAEPXW010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7483
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.147"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(296..760)
                     /locus_tag="KRM55_003381"
     CDS             complement(296..760)
                     /locus_tag="KRM55_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HBH1595572.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            complement(1084..1692)
                     /locus_tag="KRM55_003382"
     CDS             complement(1084..1692)
                     /locus_tag="KRM55_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1595573.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGFHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            complement(1774..2475)
                     /locus_tag="KRM55_003383"
     CDS             complement(1774..2475)
                     /locus_tag="KRM55_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595574.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            2687..2953
                     /locus_tag="KRM55_003384"
     CDS             2687..2953
                     /locus_tag="KRM55_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBH1595575.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            complement(3056..3475)
                     /locus_tag="KRM55_003385"
     CDS             complement(3056..3475)
                     /locus_tag="KRM55_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBH1595576.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(3742..4524)
                     /locus_tag="KRM55_003386"
     CDS             complement(3742..4524)
                     /locus_tag="KRM55_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH1595577.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKKIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            complement(4589..5350)
                     /locus_tag="KRM55_003387"
     CDS             complement(4589..5350)
                     /locus_tag="KRM55_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH1595578.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNKKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLSKKVVEQSNIKKYM"
     gene            complement(6399..7211)
                     /locus_tag="KRM55_003388"
     CDS             complement(6399..7211)
                     /locus_tag="KRM55_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1595579.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTIGLVLQK"
BASE COUNT         2497 a         1257 c          675 g         3054 t
ORIGIN      
        1 atatgatttt ttaaaatttg ctacaattat tatttatata tcaaaatata aataataatt
       61 agcttattgt taactaaatt atggaaatat acttaattga aaacttaaat ttatttcctt
      121 gtattatcaa gatttcatgc ttaccatttc caatatcatg ctcaccaact tttgatgtgc
      181 ataaactatt tcaagtaaaa atgcacaacc tatccttttt gataagaaaa agcagtcaat
      241 cataaatatc aactgctttt atgtactgaa tatcaagtta tagaaaagct ggaatttatt
      301 ttgagggttt ttctttctcc ttaactaaat tgctttcaaa agtaaccttt acaactgcat
      361 gatttatttt aattccagta aagcatatag catactcttt ctctttttgt atattagaaa
      421 gagaaattgt gaatgtatca ttatcaacgc ttccatgcca tgtattactc cataaagttt
      481 catctgtttt attgtccttt atttccacaa taccactatc tccatccatt ttaaaagaaa
      541 tctctgtgtc taaaacatct atatcattag acacacaaaa caaacgtgca ttaacaaatg
      601 ggtctgaagt atcataattt ttatctaagt ccatttcaat ggttgtttgt ccggattctt
      661 tgttgtttaa attattatat ttactttcat tgcttttttt acaagctgtc aagctaacca
      721 tactaatgat actaattaaa ataataacta attttttcat agaatttatc tcccttacaa
      781 tttctaattt ttaaccctac aaactatagt attaaactaa gctactattt tacatcaaat
      841 ttttcaatca ttcagccttt accttttctc attttaattg caaatatgtt aaataatttt
      901 ggaattttaa ttattgtagt atcttaaatt ggtttataac atattatgaa aatttaagag
      961 tcaaatcact tatttaaaaa tacacaaaat tatactttat tgtataaaaa aagagattat
     1021 aatttacaca agtaaaataa actttattat tttactcttc tatataacct cttttctata
     1081 tatctattca aataatttag ctcctaaact cacaaacatt tgtaaaatca aaaatgcttt
     1141 tgtgtctatc ttatgattac tttgtaaaat ctcttttgca tcttcttgcg aaattaaaag
     1201 cgcttcaatc tcttcatctg gttctaaaaa ttcatctgtt atatcaccat cacatataca
     1261 ataaacaaag gcaacagatt catcactcat tccaggagat aaataaactt tatcaatact
     1321 tttatttttt ttaatttcta aaagagtaag tcctgtttct tctctaagtt ctctttcaac
     1381 ggaaatatct atagactctc cttcatcaac aagacctgct ggtaactcgt atatatatcc
     1441 attaataggt actctaaatt gtcttattaa aattaatttt ttactacttt tatgaaaccc
     1501 aactattaca actgcatcta cactatcttc ttcattcttc aaataaatat tttttaattg
     1561 ctcactactt tttcttgatg ctaccatcca aaccttatct tcatctaatt tgtttttata
     1621 ctctatttca aaaagtccta taaacttatt ttcaatcatt ggatttacat tctttattat
     1681 agtttttttc aaatttacta cgacctttct tttttaatac ctttttaaca tcattaagta
     1741 aatataatat cttaacaagt attcaacaac ttattatatt tccatttcag gattatcttt
     1801 atctacaaaa cctactttaa tttcacaatt aaatatttcc tttaacaatt ttgctaattc
     1861 ttctcttgca ctcattacct tatctaaatt agcatcagta aaaccatcta taggaaaaaa
     1921 tatatttttt gagctattag taatttttcc ttcttctcct tgtctccata tccatcttct
     1981 agtttttacc atgtctccaa ctgaataaat taattctcct tcttccatta attcaacatc
     2041 agtttctcca aatggtacaa atttatcccc ttttttagaa aatctaacat atacatcatc
     2101 atttctaaaa tccatatcat gagcacccat tggaagtaaa tattttaaag aaatagagtt
     2161 tcctaaatct acaataggat ttatatgagg aagtttctta ttcttagcaa cccttgttgt
     2221 cattgcttct atcgaactca taaatttatt tgggttcatg cctagacttc taaatgcctc
     2281 tctatatggt ataatttctt ctgattcctt tactttttta tctttgaagt aatcttctac
     2341 tctatctata cttatatcta aaaggttgct tattctttct atttctttag tattatctat
     2401 tccttttgca actactacac caaagcatac attttctaat ttatcaaaaa cttctttttc
     2461 tactataaat ttcattttgc tttatcctcc tgttatttta cattattttc taaatagatt
     2521 ttatcacttt gtgtcttata aatatacccc ctatttgcta attgtttaat ttttttaaat
     2581 tttccaatta atatcaaata ttttatatgt actaattaca aatttaactt tccaaaacaa
     2641 atatcttgtt ttataatgta taatatattt ttatggaggc aagactgtga aaaattttat
     2701 tctaatatat tttatagtga ttaattctat tgctttcttt tcaatgtaca tagataagaa
     2761 aagagcaatt agaaacgaat ggagaataaa agaagctact cttatgtcta tagcagtaat
     2821 tggaggtagt ataggttcta taattggaat gtattctttt agacataaaa ctaaacacat
     2881 taaatttaca tttggtatac catttatact atttttacaa tttttattag tatattttta
     2941 tattttaaag taattgaaat ataaaacctt attcttttca ataaattaag gtgtataaaa
     3001 ttaaaaattt tatacacctt tttctagcaa ttattaaaaa gatatttaat taaaattaat
     3061 gacccttatg tttagctttt ctcttttctt gtttcaaatt aaatagtctt tctttttctt
     3121 cttcttttct atttttagct aggttttttc tatcctgttt tctttcttca tattgaagct
     3181 taagagcatt ttgagcctta gtccctatag tttctttttc ttgttccttt tttacttttc
     3241 tctgcattct tttgtatcca atgttgtctt tggtcacatt tttttctaat ttaatgctac
     3301 caaaatctaa tgagaaaaat ctttcaagta taaattcata cacttctact tctttaggtt
     3361 ctgctccaaa aactacccta catgcttcat attttttacc atcttgtctt tcaaatatac
     3421 ctacccaaaa tggttcttca aataagactg ttaattttcc actaattttg tccattgcta
     3481 gttcctcctt aaattacttt ctaaagaacg gacaaccaag gaggcaggtt actgacagcc
     3541 attgctgcgt ctggactacc aaccagactg tgtttttatc tttatagatt aaatattatc
     3601 ttttttaatc atgcttgtca atcttagtat caacatctat catattgatt taagtgaaat
     3661 caagtttttt aactctactt tattattgtt aacactaaga aaattaatta tttttcataa
     3721 taaattagtt attatactta tttaaatatc aatctttatt gttccctgca taaacaagac
     3781 tgcttcacca gaaattttca cagtattatc cttcaacact tcacactgaa ttataccacc
     3841 acgattagaa agttgagcag ctaccatttt gtgttttccc aacttttcag accagtatgg
     3901 aataagatta caatgtgatg aaccagtaac agggtcttct gaatctaatt ctggacaaaa
     3961 atatcttgat acaaaatctg tattacttcc ttgtgctgtg attattatac ctaaccagtc
     4021 tgtcaattta cgcaattgtg cgtaattagg tttataattt ataacttctt gttcactgtt
     4081 tagcaataag attaaatctc ttgaagaata aacagcactt ggtacacagc ctatcaaatt
     4141 agcttgttgc ggtgataact ctatttcaat aggcattatt tctggaaata tcatttcata
     4201 tagatttcca tttcgtgtaa cttcaagctt tccactttga gtaaagaaat ctatcttttt
     4261 tacattaaca tcaataaaat ttgatattac ataagctgct gctaaagttg catgaccaca
     4321 taaatcaatt tctgctttag gagtaaacca tcgtaattca taatttcctt tacctttaac
     4381 tacaaatgct gtttctggta aattgttttc ttctgctatt ttctgcatta actctaaagg
     4441 tattcttctg tcaagaacac aaactccagc aggatttcct ttaaatagtt tagttgcaaa
     4501 tgaatcaact atgtagtatt ccattattta acctctcttt ctaacataaa atatacatca
     4561 atttacattc aataaaactt taaatttctt acatatattt tttaatatta ctctgttcaa
     4621 caactttttt acttaacaat gtaattgctt ttttggcaca attatttaca caacgataac
     4681 acattgtaca ttgcccattt gcaacaatca tacaattttt aattactaga ttcttcattg
     4741 gacataaatt aacacattta ccacatacaa tacattcctc agtattaatt tttagtttat
     4801 ctgtatacat atttgtttta ttgataaaat acaatcgttg tccaaataac cctacaatat
     4861 gactcaaaaa acccaaccct tcttttggtg gtgacccatg tttcagtttt ttagcagcct
     4921 tagttacttt cttttctgct tttattacaa gctttttatt gtactctaaa gaatgtttta
     4981 ataccttttc atctcctata ctatctggca tcttcacatg taatccacca acagttatag
     5041 caccgtattt ttttaatatt ctagataaca caccagagcc atctccacta aatagagcca
     5101 tagttgcaat aataaaaaca cgtttaccat tccacaaagt tgaatgattt attataaaat
     5161 ctttcaatat ttttggcaca ttactatatt gcacaggata actaaaaata atattctcat
     5221 gattattgat gtgctgtaaa agttcattat cttcaataga ataagaattt gctgttatat
     5281 catattcttg taaaaatttt tctacacagt atcttgaatt tcctgttcca ctaaaatata
     5341 ttcctatcat agtacttctc ctaatagcta agattatata gctctattct taaaattctg
     5401 actttttata ttatctaaat taagtagttt atttaaataa tataaactta attcaacaag
     5461 ttacctactg aacctcccat gactaaagtc atagggttcc tgcttgatag aattttgcat
     5521 aatcaattta ctaaatactt gtctaattct ttttttatca ttttaaatat acattttaat
     5581 aatattagta agctatactt ccttaagcat atattttccc taaagtaaaa ctattgatga
     5641 ttattccatt atataaccta attataaatt tagtaagttc atcacatact atacccttaa
     5701 ttctcaatta taaagttccc taaaaaatat ttgaaaattt aactataaaa aaattcccta
     5761 ttgcctaata tgtataagta aggagtacta tatagtactc cttatattgt actcttataa
     5821 cattgatgcg ttaatattat tttaatctta atcattattg atttgattta aaattataaa
     5881 taggttccaa tattttaatt atgtcaacta tatctcttat agttttaata atctcatcaa
     5941 ttggtttatg tgcttgttgc actttatcaa tagtattaat taaatccatt tacacatcta
     6001 gcacctgtat ggcaatttag cattatcctt atcttatact ttgttgtaaa ttcttgatta
     6061 cataattcta ttatctaact tatagctgtg caatctacat tatctgtaaa tatctttgct
     6121 ttatatattt tccctgaacc tctaacatta atataacagc ctttttgcta tacactttta
     6181 actatatact taattttaat aacattactt gtttataaaa atatactata gataaatttc
     6241 acataaaaat aataattcaa gtattgattt ttatataagc aaatttgtaa tgtactaaaa
     6301 ataacataaa agtttccatt tttcaatatg taagctttta ttatgttatt ttattgttaa
     6361 aggtttcaag tttttattta ttcattaaaa aaaaattatt atttttgtaa aactaatcct
     6421 atagtcatac tatcgtcaga atatgcttca cccttaacat tactaaaaaa ctcaacagac
     6481 ttaaatccaa tattttcaac ttctaataag aaactttctt ttgaaaaata gtgattccaa
     6541 acataaaaca cattttcatc tttttcggtt attacaagag tttgttctaa tgtattataa
     6601 tcattgtatt tacaattatc ttgtagacac atatattttt cattactcca aaatcctcca
     6661 tcttcattta tttcccaata tttaatttcc tcaaaattat tgtatttatt tattgtaaat
     6721 acatctaata ttaattttcc tccaggtttt aaactatcat aaattttttc cattaataac
     6781 cttctatttt cagttgacaa agctccataa tcacaataaa ttaaagtagc caaatcaaat
     6841 tcctcattat agttcatatt taaataactt tgaaacaagt aatttatgtt taaattagtc
     6901 tccttatttc tattttgtgc atagttaata gaacgttttg agaaatcaat tccagttacc
     6961 ttataacctt tttgtgcaaa tttctctgca tataaacctg gaccacaacc taaatcaagt
     7021 aatttaggat aattagctgg atttgcaact gtaactatcc aatttacaga atcctcgata
     7081 aagttaaaat ttctacttgc tccttcaaaa ttagtgtcta agtgtgcttt taataattgc
     7141 tttgaaatat actcatcatc ccaaaaatta atctcacttt gtttataaag ctctggtctt
     7201 tctaaataca tacataattt gtttaacaaa acataccact ccttaaaatt tatttttaaa
     7261 ataaaaaaac cacagagttt actctgtggt ttaacttcaa aaagatgagt ttaaataaga
     7321 gtaaaataga accaaatatt tttaagcaca acaataaaac tatagcttta ctttgtttgc
     7381 ttattaaatt tgattttatt cactcttttc cagcaatact tatatcaacg attttatgat
     7441 atcaaatatc accgaacaac atcatccttt catattttta ttt
//
LOCUS       DAEPXW010000144         7441 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.148, whole genome shotgun sequence.
ACCESSION   DAEPXW010000144 DAEPXW010000000
VERSION     DAEPXW010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7441
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.148"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            61..1038
                     /locus_tag="KRM55_003389"
     CDS             61..1038
                     /locus_tag="KRM55_003389"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBH1595580.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPNMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            1031..1999
                     /locus_tag="KRM55_003390"
     CDS             1031..1999
                     /locus_tag="KRM55_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBH1595581.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLVVSALIAVNALGDVYENGKVIAGALNDKRTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            2182..2772
                     /locus_tag="KRM55_003391"
     CDS             2182..2772
                     /locus_tag="KRM55_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1595582.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            2791..3561
                     /locus_tag="KRM55_003392"
     CDS             2791..3561
                     /locus_tag="KRM55_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBH1595583.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            3698..4666
                     /gene="dusB"
                     /locus_tag="KRM55_003393"
     CDS             3698..4666
                     /gene="dusB"
                     /locus_tag="KRM55_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBH1595584.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            4775..5254
                     /gene="greA"
                     /locus_tag="KRM55_003394"
     CDS             4775..5254
                     /gene="greA"
                     /locus_tag="KRM55_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBH1595585.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            5269..6798
                     /gene="lysS"
                     /locus_tag="KRM55_003395"
     CDS             5269..6798
                     /gene="lysS"
                     /locus_tag="KRM55_003395"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBH1595586.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            7107..7301
                     /locus_tag="KRM55_003396"
     CDS             7107..7301
                     /locus_tag="KRM55_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595587.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
BASE COUNT         2960 a          754 c         1509 g         2218 t
ORIGIN      
        1 tgtataatta tttattagaa gaaaataagt catgaaatta tgtcatatta gaggtgaaat
       61 atgcgagata aaataataga gattatatta aataataaat ctgaatttat ttcaggagaa
      121 gaattatcaa aacaattagg ggtgtcacgt gcagctatat ggaaacatat gaaagcctta
      181 aaagaagagg gatataatat agaatctgta aataaaaaag ggtatcgatt agcggaaaat
      241 ccaactgatt tattaagccc acagaatatt tactataaat tagatacaga gtttattgga
      301 aaaaatattg aacatcttga cactatagat tcaacaaatg aacatgctaa aaggatagct
      361 ataaatagtg tagatgggac tgtgatttta agtgaacatc aagacatggg gaaaggacga
      421 ttgggaagaa gatgggattc aaaacctcat gaaggaatct ggatgagtat tatattaaaa
      481 ccaaatatgg aaccattcaa agctccattt ataactttaa tagcaggagc aagtgtaacg
      541 aaagctttaa acaatctagg agcaaataca ttaataaaat ggccaaatga tgttatttta
      601 aatggaaaaa aaatatgtgg tatattaaca gagttatctg ctgaaattga aagaacaaat
      661 tatgttgttc ttggaattgg aataaatgtt aaaataatgg attttgaaca agaaatagct
      721 gacaaagcca catcattgta taaagaaggg tatatgttat ccagagtaga tattgttagg
      781 aatgtattga ctgaatttga aaaattatat ttagattata ctgtaaataa ttccaaagaa
      841 aaaaccttaa aaatatgtag agattattct gcaattatag ataaaaatat atatgtatta
      901 aaaggagata atagagaact agtgaaatgt ttagacataa atgaagaggg aaatttatta
      961 gttcaaagaa gtgatggaag tataaaagaa attatttcag gtgaagtttc tataagagga
     1021 gaaaaaggat atgtataata atattttgga tatagaaggc ttaaaggttg ggcaggttga
     1081 ggatagaaat ggtcttactg ggtgcacagt agtaatatgt gaagaaggag ctacttgcgg
     1141 tgttgatgta aggggctctg ctccaggtac tagagaaacc gatttattag accctgtaaa
     1201 tatggttcaa aaagttcatg cagtagtttt ggctggaggt tctgcatatg gtcttgaatc
     1261 cacttgtggt gtaagtagat acttagaaga aaaaggaatt ggatttgatg taggtgtagg
     1321 taaagtgcct atagttgtag gagcagtttt atttgattta ggagtaggga gctttaaatg
     1381 tagaccagat ttaaagatgg gttatagagc ttgtgaagtt gcaaatactg atattttaaa
     1441 tcaaggaaat tatggagcag gttgtggagc cactgttgga aagataagag gtcaggaata
     1501 tgctatgaaa ggcggaatag gtagctattc tataaaatta gataatggtc tagttgtatc
     1561 tgcattaatt gctgtaaatg ctcttggaga tgtttatgaa aatggtaagg ttatagctgg
     1621 tgctttaaat gataaaagga cagaaacaat tgatacatat aaattaatga aacaaggtga
     1681 aagtaaaggt ggatttagtg tagataatac tacaattggg ataattgcaa caaatgctaa
     1741 gttaaccaaa gctggatgta aaaagatatc tcaaatggga catgatggat atgctaagtc
     1801 tatttttcct atccatacac ctcatgatgg agatacaata ttcacaatat caacaggaga
     1861 aatagaagca gatataacat tagtaggttc attggctgta gaggttgtgg aaaaaagtat
     1921 aataaatgca gtaaaaaaag cggatagtgt agaaaatata atggcatata aagatatagt
     1981 aaaaaaacga gaaatatgat gaaattagca tatttttctt gtcaaattgt tgacaatggc
     2041 aactcatctt gataaaatta ttcttgttag agcgggcatc ctacaatggt agcttgactc
     2101 ataattataa gaaaaaaacg aaaaaattaa aaaattaagt agtccggcat cttaatgagc
     2161 tggaacggag gtgtattttt tatgatgaac acaagtgcat cagtaagaaa agtaaatgta
     2221 agaaagatga ctataatagg agtactatca gctatttcta ttatgctatc tatgactcca
     2281 ttgggattta ttccagttgg acctacaaaa gcaactataa tgcacatacc agttattatt
     2341 ggagctatta tggaaggacc aatagttggg gcagcaatag gatttatatt tgggatatca
     2401 agtctcttaa atgctataac aaacccaaca gtaacatctt ttgtttttat aaatccatta
     2461 gtttcaatat taccaagagt tatgataggt gtattagctt attatgtata tcagttaata
     2521 attaaggcta caaataaggt atacatatca ggtttaatta caggggcaat aggttctctg
     2581 ttaaatacag ctggagtttt aggaatgata tatgtcttat atgctgacaa gtatcttcat
     2641 gcaatgggta aaagtggttc agcaggaaaa gtaataatgg ctcttgccgc agcaaatggg
     2701 gtgccagaag caatagtagg ggctttagta gtagctgctg ttgccactgt acttaagaaa
     2761 agcaaaaaat agaaagaagg ttaatgacat atgcttctag tatttgatgt tggaaatact
     2821 aatatggttt taggtatata taaaggtgat aaattagtta attactggag aattaaaaca
     2881 gatagggaaa aaacgtctga tgaatatgga atcctgataa gtaacctatt tgattatgat
     2941 aatgtgaata taagtgatat tgatgatgtt ataatatcat ctgtagttcc gaatgttatg
     3001 cattctcttg aaaacttttg tataaagtac tgtaaaaaac agccattaat agtaggtcca
     3061 ggcataaaaa caggtctaaa tataaaatat gataatccaa aacaagttgg ggcagataga
     3121 atagttaatg ctgtagcagg gatagaaaag tatggagcac caagtatact tgttgatttt
     3181 ggaacagcaa ctacattttg tgctatctct gaaaaaggtg aatatttggg tggaacaata
     3241 gcaccaggaa taaaaatatc tagtgaggcg ttatttcaaa gtgcgtctaa attacctaga
     3301 gtagaattag ctaagccagg tatgactatt tgtaagagta ctgtatcagc catgcaatct
     3361 ggaataattt atggatatgt tggtttagtt gacaaaataa taagtatgat gaagaaagaa
     3421 ttgaattgtg atgatgttaa ggttatagct acaggtggat tagctaaact gattgcttca
     3481 gagacgaaaa gtatagatta tgtagatggt tttttaacac tagaaggatt gagaataata
     3541 tatgaaaaaa accaagaata attaatatac agggaattgg gttatatatc caattccctt
     3601 tttatgatag atttctagct atatgtggta tattataatg aggaaataag aatttaaagt
     3661 taaatcacaa aataaaggca aaaataggag aaaaacaatg aaaataggaa atttagaatt
     3721 gaaaaataaa gtttttctat cacctatggc aggtgtaaca gaccttccat ttagattaat
     3781 ttgtaaagaa cagggatgtg ggcttttata tacagaaatg ataaatggta aggcactttg
     3841 ctatgatgat gaaaatacta aaaaaatgct taagatagaa gaggaagaac atcctgtagc
     3901 agttcagata ttcggttcag aaccagagtt tatgggaaga gcagcagaga taatgaatga
     3961 ttattcaaat gagattctcg atataaatat ggggtgtcca gctccaaaag tagttaaaaa
     4021 tggagatggc tcagcactta tgaaaaatcc taagcttgca gaagaggtat tgagggcagt
     4081 agtgaagaac tcaaaaaagc cagtgacttt aaagattcga aaaggctggg atgataatag
     4141 tgtaaatgct gttgaaatag caaagatagc agaggattgt ggaataagtg ctttagcaat
     4201 acatggaaga actagagaac agttttatac aggcaaagca gactgggata taattgcaga
     4261 gattaagaaa aatttgagta tacctgttat aggaaatggt gatgtattta caatagaaga
     4321 ttcaataaat atgttagaca aaactggttg tgatgctata atgataggta ggggtgctca
     4381 aggtaaccct tggatattta aaagaataaa ccattatatg aatacaggcg agattttgcc
     4441 agagccaact cttaacgaaa aaataagtac tgccattaag catttaaaac ttgcagtaga
     4501 agaacatgga gagtatgtag ctgtaaggga aatgagaaaa cacatcgctt ggtatttaaa
     4561 aggacttaga aactctgcaa aattaaggga tgaaattaac aaaatagaag actatcaaga
     4621 agttgtgtcg aaattggagt actatatgga agactccttg acataaaaat aatagtgact
     4681 tataatatag cgcataaatt aaaaaaagat tataaaattt ttaaaatata attaggaaaa
     4741 ttcctaagaa atttgtgaag gagttgtatt tataatggaa gaaaataaag agtttttatt
     4801 gacacaagag ggatatgata aattagaaga agaattagaa aacttaaagg ttgtaaagag
     4861 aaaagaagtt gcagagagaa taaaagttgc tatatctttt ggtgatttat ctgaaaatgc
     4921 tgagtatgat gaagctaaaa aggaacaagc acaagttgaa gaaagaattt taaaattaga
     4981 aaatatggtt agaaaagctg ttatcataga tgaaagcaaa atagacctta atgttgttac
     5041 aataggatca atagttaaag ttaaggattt agaatttgat gaagaggttg aatatactat
     5101 agttggttcg acagaagcag acccatatga tggtaaaata tcaaacgaat ctcctgtagg
     5161 gaaagcactt ttaggtagag ctgcgaaaga agttgtggaa gtgcaagttc ctgatggagt
     5221 tgctaagttt gaaatattag aaataagaag ataatttgga ggaaaaaaat gaaaaataat
     5281 caacaaagca atgaagaagc gcaaattcaa gaagacctta gtgaagtact tcaagtaaga
     5341 agagataaac taaaaaaatt acaagagtca ggtagagatc cttttaaaga aagtagatat
     5401 gatagaactc attattctat ggatataaaa gataactttg attctcttga aggtaaaact
     5461 acaaaaatag caggacgtat aatgagcaag agaatacaag gaaaagctgg ctttatagat
     5521 attcaagacc aagagggaag aatccaatct tatgtaagac tagatgctat aggagaggaa
     5581 gaatatagtg tattttcaac atatgatatt ggagatatag ttggaattga aggagaaatc
     5641 tttaaaacta aaaaaggtga aatatctgta aaggctaaat ctgtagtatt actatgtaaa
     5701 tctttacaag ttttaccaga aaaatatcat ggattaaaag accaagaact aagatataga
     5761 caaagatatg ttgacttaat agtaaatcca gaagtaaaaa atgctttttt aattagaaca
     5821 aaagcattaa aagcattaag agcatactta gatgatagag gatttttaga agttgagact
     5881 ccaatattaa atactatagc aggtggggca aatgctagac catttataac taatcataat
     5941 actttacata taccaatgta tttaagaata gcgaatgaat tgtatttaaa aagacttatt
     6001 gttggtggat ttgataaagt ttatgaaatg ggaagaatgt ttagaaatga aggtatggat
     6061 ttaaaacata atcctgaata tactgcaata gaattatatc aagcatatgc agactatact
     6121 gatatgatgg aaataacaga aaatgttatt gcacatatgg ctgaagttgc tacaggaagt
     6181 atgatagtta actatcaagg aacagaaata aactttacac caccttggaa aagaatgagt
     6241 atggaagatt gtgttaaaga atattctggt gtagattttt ctactataaa tacagatgaa
     6301 gaggcactag aagttgctag ggaaaaaggt atagagataa aacctggaat gagaagaggg
     6361 gaagtaataa atgctttctt tgaagaattt ggagaagata aattaatcca accaacattt
     6421 ataactcatc atccagttga agtatctcca ttatctaaga gaaatgttga agacccaaga
     6481 agaactgata gatttgaggc atttgctaat aagtgggagt tagctaatgc attttctgaa
     6541 cttaatgacc ctattgacca aaaaggaaga tttatagacc aattaagaaa aagagaatta
     6601 ggtgatgatg aagcttttga aatggatgaa gatttcttaa aagcattaga ggtaggtcta
     6661 cctcctacag gaggactagg aataggtata gatagagtaa ttatgttatt aactaactct
     6721 ccatctataa gagatgtatt attattcccg actatgaaac ctattgataa caatccaaat
     6781 aaagaagaag aaaactaaga aatattagca ttctactaag ttttaaataa agtttagcta
     6841 ttaaattatc aataaatagc taaattttat ttaaaatgtc agtgtagaat gctttttata
     6901 tgcttcaaag attcttttag atatttaatt tataaattac caacaaacgt tagaaattga
     6961 tattagtttt tgttgattga gactttatat ttagaaaata tgattgaaag taatttatta
     7021 tgaaaatatt tagaataatt tatgagaagg taaaaagaat aatttatgag aatactatat
     7081 ataaaaaatt attgggggaa tgtctgatgt ttcaagtaat taatttttta tgtttatttt
     7141 gtgttggatt tttggttctt gatgttatga tatatttttg taaggatgca atggatattt
     7201 ttgagggtac aactaatgtt aataaagtta agagtataaa tgtttgggca gatagagtga
     7261 gagctaattc atattcttat gaaaataaaa ttgcaaaata ggtaaaatta tatatgcatg
     7321 cattgtttgt aatatcaagg gttatatcta ttagttttaa ttatatttat taaaaaaaac
     7381 caaaagttat aacctttttt aaaataaaaa acaaaaaaag tattgacgaa ttatttttaa
     7441 g
//
LOCUS       DAEPXW010000145         7409 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.149, whole genome shotgun sequence.
ACCESSION   DAEPXW010000145 DAEPXW010000000
VERSION     DAEPXW010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7409
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.149"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(<1..1226)
                     /locus_tag="KRM55_003397"
     CDS             complement(<1..1226)
                     /locus_tag="KRM55_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595588.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILL
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLK"
     gene            complement(1226..1972)
                     /locus_tag="KRM55_003398"
     CDS             complement(1226..1972)
                     /locus_tag="KRM55_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595589.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGESIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            complement(2119..4338)
                     /locus_tag="KRM55_003399"
     CDS             complement(2119..4338)
                     /locus_tag="KRM55_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1595590.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNVKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIASNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFIAPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            complement(4704..6098)
                     /gene="gltA"
                     /locus_tag="KRM55_003400"
     CDS             complement(4704..6098)
                     /gene="gltA"
                     /locus_tag="KRM55_003400"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBH1595591.1"
                     /translation="MDAKKVKVPVREQEPEVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            complement(6098..6991)
                     /locus_tag="KRM55_003401"
     CDS             complement(6098..6991)
                     /locus_tag="KRM55_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBH1595592.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
BASE COUNT         2452 a         1330 c          709 g         2918 t
ORIGIN      
        1 ttttttaatt gttttaaaga atttatatgt tcttgtgaat tgctactagg aattataatc
       61 ccttcatatt tttctaactt tgaactaatt ttatctaatc ccaattcctt tgataatttg
      121 ttataattct ttacacttag taagacttcc ctattatatt taagtacagg aaaacttaac
      181 tccttataat catatccttt gattgcttct ctaatttgtt gtagttcttc atattctttt
      241 tcattattat gctctgaaaa atatgagtaa accattggga aattattttt agaagcttct
      301 ccttgagagc ttacaagtgt tgaagttgtt gtaaatgcta ctaaagtagc cgataaaagt
      361 attgttatta aaaataacaa tcgtgtatta tcctttaatt tatatatcaa attacttata
      421 agtaacatat ttactttgtt cttataaaat ttttctttat tttttaaata ctttaatatc
      481 aaaatagtaa attgagaaaa aaataaaaat atccccaaag taattaatag tgctgttgta
      541 tacatacctc catttatttt taacttattg ccaagtagta tcatagcata tcctaatata
      601 agacatatta caccaattat tccaaatagc tttgaagatt ttatctcttt tttaggcttt
      661 tttgtaccta ctaaaagctc taaaatgctc tttttactca ataattttaa gctcattggt
      721 cctgttatca aaaataaaat cataaatgat acaatagtca atagcattgc ttttactgga
      781 aaataaaatt cagttaaatt catataaaac agtttgctta aatacaataa aaacaatttt
      841 gaaattgata aaccaagtaa tattcctaac atcactgcta aaaatcctat tatcaaattt
      901 tcaattaata tcaatttttt cagttgtctg ttactcattc caattatcat caatactcca
      961 aaatctttca atctatattt taagaaattt cctaaagagt acaatataaa aagtagacta
     1021 aaaccgaata ttattaattc tgaagtcata agagccataa atgcagtaga accactctgc
     1081 attccagatt ttgttataat tggatggaac atagacactg caaaaacaaa aaatatcatt
     1141 atagaaaaaa cagaacttaa aaaatatgct aaatatgccc tgaaatttct aactatatta
     1201 ttataagcaa actttctaaa atccactatc ttacacctcc tatttgagac aaaacagcta
     1261 gtatatcaga atagaaagaa ttactgcttt cagatttttt tatttctgta tatatacaac
     1321 catcttttat aaaaattact ctatctgaat aacttgcact atatgcttca tgagttacca
     1381 taagtgttgt taccttttgt tctttgttta tcctagtaaa taatttcaaa acatcatcag
     1441 tagattttga atcaagattt ccagttggct catctgcaag aagtatggca ggtttattta
     1501 taatagctct agcaatagca cacctttgag cttgacctcc tgaaatttca taggtttttc
     1561 tatctaaaat tttatctatt cctaaaaatt tagatatact tttagtttgt atattcatat
     1621 ctttgatact ttccccctct agtgtaagtg gcaacataat attttcgcca acagttaaag
     1681 tgtcaatcaa attaaaatcc tgaaatacaa aaccaagttg tttccttcta aattcagcaa
     1741 gtttttctcc tttcaattta cttacatcat atccatctaa tacaacctca ccttcactct
     1801 gtctatcaac tgtagatatt atatttaaaa gagtagattt accacttcca gatggtccca
     1861 taacagacac aaattctccc ttttctatat ttagactaac cttatctaat gctttaaatg
     1921 gaatatttcc acaatatgtt tttgatatat ttctaatact caatatgttc attttatatt
     1981 ctccataatt ttttattttt actacaatac cataatatcg tgaatatact actttaacca
     2041 taaaaatacc ctaacaatta acttacatat ttgtaagtaa gttgttaggg tatcttatag
     2101 tctaataatt attaatgatt aatcaaattt aaagtttaag tgtttttcaa attcatctaa
     2161 taccataggt ttagcaaata agtatccttg aaccttatca caacctatct ctttcaagaa
     2221 ctctacttgt tcataagttt ctacgccctc acagattact ttaatatcaa tcgcttttgc
     2281 catttccaca atcttagaaa taataatttt tccacgtttt gtatctgttg tttcgattaa
     2341 aaatcctcta tctaatttta aaatatcaaa agaaaggtct tttaacagat ttaaagatga
     2401 atatcccgaa ccaaaatcat ccattgatat aaggaatcct atctctttaa tctttttcat
     2461 tatatcaatc aatatattta aattatcaaa cacaacactt tctgttagtt caagttcaat
     2521 aaactcagga gatatattgt atttacttat caaatcagtt atattttcta taaaattatc
     2581 cctatataaa tgaactctag acatatttac agagattggt acaggagtat accctttatt
     2641 tatccacttg tttaatgttt tgcatacttc ttcaaacacg aacatatcaa tatttacaat
     2701 aaaaccattc ttttcaaata aaggtacaaa atctataggt gcaataaacc caaattctgg
     2761 actattccat cttatcaagg cttctgctcc ttcaatttca tttacatcat ctaaactata
     2821 cttaggttga taatatacta taaattcacc tttttctaaa gctttattca tattatcttc
     2881 caatcgtttt tccttgtaca atcgatttct tgtatcttca ttaaaaaatg aatatgaatg
     2941 ttcatatttt tcctttttac tttttgctgc aatatttgct ctatcaatta acaagtcaat
     3001 ctttttaata tcatcctttt tagtaatctt atatattcca cttgacataa caattttata
     3061 cttagatgag ttagtagtat ttaagttaca aatttcttta tttattttag ataatctatt
     3121 taaaagttca tcttcagtgt tagaagcaat caacaatata aaatggtcat tatccatcct
     3181 agcacaaatt tcatatttat ttgtattatt atttaaaacc tgtgatatat gaattaatat
     3241 cttattccct tcagcatatc caaacatctc atttatatat ttaaatttat taacatccaa
     3301 ttgtactaag taaaaattat cttgataata attctttaaa atatacatag aatcttttct
     3361 aaacttttct ttatttttta ttccacttaa agaatcataa taagccaatt ttttaagttg
     3421 ttctattaat ttagcattac ttaatttcca caatatcata aatattacta tataaaaata
     3481 caactttatc ataaaattaa ctattagatt tttaaagttc ttaaatatat tacattttga
     3541 tactaaagtc caattagtcc actttacgtt cgtatatttt acattatata atctccaatt
     3601 atcccaagat aaaaaatcac cttgacattt tttatttata ttttttaaga tttcactttt
     3661 agtggttcct ataatattcc cttctaaatc aagcatctta cttttatcat ttacatattt
     3721 tttgtttgga tgagaaataa tagtataatc tttatctatc attagaaatt taatagaatc
     3781 atcaaaattg cttctactta ttaaattatt tacatcttga aaataaaaag aagcaaaaat
     3841 ggtcccaatc atctcattat tttttacaat tggtacatat atgataaata ctttgtcacc
     3901 tgttacatta ctgacttcaa tatctgaaac tactacttgc tttgttttaa ttgctttctc
     3961 aaaactaggc ttatctttta ttgagttaac attttcccta tatgtacttg aagcatttcc
     4021 ttttgtatct gttataccaa tcataaaaag attatattcc ttttgatatg gacttaataa
     4081 ttttcccttt tcaattagtg atgtttcacc attagaaaat ctatcatctt gactaagagc
     4141 ttttaataaa gatatgttta cttctaaata gttttcaagt tctctttttg atgcctcaat
     4201 catatttcta gaagtaattt ccatagagtt acttgcatat atgatggtac ttgttaaatc
     4261 aatcaaaact aatagtatta ataagattaa tatatgctta aaaactagcc catcaaatac
     4321 tttttctctt tttttcatat taaaatacca ttaattacac aatttatttt tctattattt
     4381 aatgttagat ttgacaaatc tgattttatt agccacacat tattcactcc ttacaagacc
     4441 tttattgtat aactatttta tcatagttag acaaagttat gttacttagt atcaaatatt
     4501 acaataataa ctgataaatt attaaaccat ctaaaaaagt ggctacatca aaatagagat
     4561 tgtactaaga cctaaaagtt agactttcta caggaatgaa attttcattg ttgaaatgat
     4621 taaaacatat ttgattttgt acaaaaagag tgcctcatga actaaaaagt tcattttgag
     4681 acaccctctc tttaatttac aaattaagca ttaacttttg cttttaaata ttcatctatt
     4741 gatgctgctg ctgttttacc agcacccatt gcagatatta ccgttgctgc tccagtaaca
     4801 gcatctccac ctgcaaatac accctcttta gaagtctgac cattttcatc tgttattaag
     4861 catctcttct tatttatatc aagactcttt gttgtagaag atattagtgg atttgggctt
     4921 gttccaagtg acattataac tgtgtctaca tcaagtacaa attcagaacc ttctatttct
     4981 ataggtcttc ttcttccaga atcatctggc tctcctaatt ccattcttat acaaaccata
     5041 cctttaacat atccattttc atctactaaa atttccttag gatttgttaa tgtattaaat
     5101 ataatgcctt cttcttttgc atgatgaact tcttcagctc ttgctggaag ctctttttca
     5161 cttctcctat aaactatata tgattctgaa cctaatctta atgcagttct agcagcgtcc
     5221 atagcaacat ttccaccacc tactacagca acttttttac cagaactaat aggtgtatca
     5281 taatcatctc tataagcctt cattaagttt actctagtta aaaactcatt tgcagaaaat
     5341 actccatttg cattttcccc tggtatattc ataaacattg gaagaccagc tcctgaacct
     5401 atgaatatag cttcaaatcc ttcatcttct ataagttcat ctactgtaat tgttttacca
     5461 acaattacat tagtttctat ttttacacct aattttctta tattgtctat ttcaggttga
     5521 acaacagctt gttttggaag tctaaactca ggtattccgt aagttaaaac tccacctggc
     5581 tcatgcattg cttcaaagat tgttacatca tagccttttt tagctaaatc accagcacaa
     5641 gctagacctg ctggaccact tcctattact gctacttttt gatttttctt aggctctgta
     5701 tcagataaat ttatgtcatt ttcttttgac caatctgcta caaatctttc caatttacct
     5761 attgatacag catctgattt tattccaagt atacatacac cttcacattg actttcttgt
     5821 gggcatactc taccacaaac agctggtaat gaactgctct tagctattac tttagcagca
     5881 ccttctatat catcttcttt aatttttgtt ataaaccctg gtatgtcgat tcctactgga
     5941 catccaccca cacattttgg ttttttacaa gctaaacatc tattagcttc tgccatagct
     6001 tcttctttat tataccctaa gcatacctca tcaaaatttg ttgctctcac ttcaggttct
     6061 tgttctctaa ctggtacttt tactttttta gcatccatta tttgttacct ccacatccac
     6121 aattactatg atgatgacta tcgccttctt caagttttag catagctctt ccctcttgag
     6181 tcttgtacat agactgtctt ctcattgctt gatcaaaatc aactaaatga ccatcaaatt
     6241 caggaccatc tacacatgca aacttagttt catttccaac actaactcta caaccaccac
     6301 acatacctgt tccatctatc attattgtat ttaaacttac tatagtaggt atatttagtt
     6361 ctttagttaa ttggcacata aatttcatca ttatcattgg tccaattact attgcttggt
     6421 cgtatttttt accttgatta tcaactaaat cctttaatag gtctgtaact cttccattaa
     6481 atccatatgt accatcatct gttgatacat atacattttt agctactttt ttcatatcat
     6541 cttctaatat aattaattct ttagttcttg caccaattat tacatctaca tctaatccat
     6601 gctctttaaa ccatttaact tgtggataaa ctggagcaga accaactcca ccagctacaa
     6661 ataatatctt tttatttctt aattcttcta tatcttcatg tataaattca cttgcttgtc
     6721 ctaatggccc tacaaaatcc attacaaaat cgttttcttc aaacattgct aactttttag
     6781 ttgaagcacc aactgtttgg aatacaatag ttactgttcc tttttctcta tcatagtcag
     6841 ctattgtaag aggaatcctc tctccttttt catcattttt aattattata aattgacctg
     6901 gttgagaaga ttttgcaact ctaggtgcct ctatttccat taaataaata ctatctgtta
     6961 attgtctctt actaactatt ttattactca tctcgctatt ctccattcta acaaatatat
     7021 ttttcccact ttaaatttaa ttaaaaacat aaacacacaa aactataact ctttataata
     7081 taatattagt tcttggttga ttgttttgta ttggacatcc cccctataat aattataact
     7141 gcccaaacta caaatagttg atattaacaa atttcttgta aatgccaata aacactaagt
     7201 ctatatcata cgtctaattt gttatagatt taacctaata cacacttaaa gtatactata
     7261 ttatgccaaa tttgtaacaa aaattttata aatacataat aaaatttttt tattcaatta
     7321 tttatttaat aaattaactt aggttttcat aataacacta atttctttaa aaactaaacg
     7381 tgtataaggc tttaatctat tgcaatacc
//
LOCUS       DAEPXW010000146         7264 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.150, whole genome shotgun sequence.
ACCESSION   DAEPXW010000146 DAEPXW010000000
VERSION     DAEPXW010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7264
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.150"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(215..1054)
                     /locus_tag="KRM55_003402"
     CDS             complement(215..1054)
                     /locus_tag="KRM55_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1595593.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMCILIVVGAITGIL
                     GLF"
     gene            complement(1078..1836)
                     /locus_tag="KRM55_003403"
     CDS             complement(1078..1836)
                     /locus_tag="KRM55_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1595594.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1883..2356)
                     /locus_tag="KRM55_003404"
     CDS             complement(1883..2356)
                     /locus_tag="KRM55_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1595595.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2385..2801)
                     /locus_tag="KRM55_003405"
     CDS             complement(2385..2801)
                     /locus_tag="KRM55_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1595596.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2848..3900)
                     /locus_tag="KRM55_003406"
     CDS             complement(2848..3900)
                     /locus_tag="KRM55_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1595597.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4296..4976
                     /locus_tag="KRM55_003407"
     CDS             4296..4976
                     /locus_tag="KRM55_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH1595598.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5109..5429)
                     /gene="sugE"
                     /locus_tag="KRM55_003408"
     CDS             complement(5109..5429)
                     /gene="sugE"
                     /locus_tag="KRM55_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBH1595599.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            5811..6638
                     /locus_tag="KRM55_003409"
     CDS             5811..6638
                     /locus_tag="KRM55_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH1595600.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGSKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
BASE COUNT         2460 a         1315 c          848 g         2641 t
ORIGIN      
        1 ttttatataa aaatgaaaaa gcacctcatt ctgattaaaa atctttctga gatacttttt
       61 aaaatattaa atactacata tagcttacat aagtttaaaa tttaatctat tataaaatta
      121 ccctaattgc caaacttttt aatataaatt ttccaacatc ctacaaatat aatcaataga
      181 tatagaatcc taacttacac caatatatat ttatttaaaa tagtcctaaa atacctgtaa
      241 tagctcccac tactatcagt atacacatta tttttattgg agaaagacct ttttttaaag
      301 caaagagtac taataaagta agtaccaaag gaattaaccc aggaaatatc ttatcaagta
      361 aatccgtttg aagactaaat ttaaaatcac cactagtata acttattggt gtagataaat
      421 taataaacct acctacaagt ccccccatga ctaaggtacc tagtatagaa gccccttcta
      481 taaccttatt tactattcca ccttgaagta tactttcaac agcttttttc ccatacttat
      541 atccatttgt ccacattcca aaagaaattg aagtcattat tatatattga gctattacaa
      601 ataatatagg tcctgcaatt gatgctcctc cctcagttaa accaatacaa acagccaaca
      661 ctataggagt tataactcct tgagttaaag tatcgccaat tcccgctagt ggacccatca
      721 agcctgtttt gatagcattc ataccatctc cacttatttc atctgctcca ttagcttttt
      781 cttcttccat agctattgtt attccatgta taacacatcc acatataggt tctgtgttaa
      841 aaaatgctag atgagtctcc acttcttgtt ttaactcttc cttatctgga tataattttt
      901 taagtactgg caacattgaa tgtgaaaaag ctgttgattg caatctttca taattgtaat
      961 tagattgtgc aaagaaaaac catcttaacc atgattttat tacatctttc ttgcttaacg
     1021 ttttcttaga tacttcattt tttatatctg acataatatt ttccccctca catgtattta
     1081 agatgtagca ctatcttttc cgtacttaat tgaagtaatt gtaagagcaa gtattactcc
     1141 aataacagat attactatta tatctacttt aaaataaaca gccattagta ttcctaatat
     1201 gaaaaagggc atagtaaact tgtttccaat caattttaaa ttcatagcaa tcccaagtgc
     1261 tggcaacata gccccaatta cattaaatac atgtaacaca ttatcattca ttacttccaa
     1321 cataccatct atcgcatttg gaccaaaata aacaactaat aatgctggta taaaactcat
     1381 tgcaaataac agtatctgtg gtggtactat atttataaat gctactctat caacattccc
     1441 tttttgaacc tctctatcag cccaatgtgc aaaaaaagaa tttactgtca tctttccaat
     1501 ccaaagtaca gttgcaacag ttcccaatgg tacagctatt gccattgcag tacttacatc
     1561 tagcttagat gctatagcta aagcagtacc tacatatcct gcaaaagctg ggtcccccat
     1621 ctgagctccc cctgctgata taaaacctag atatatcata tttatacctg ctcctataat
     1681 tgctccttga acagggtctc ctaatataat tcccgttaca aatccagcca atagaggtct
     1741 attccatgta aaaaatccaa cataagtcaa ccacggactc caagaaagat aataaaaaat
     1801 tgctattaat actgcttgaa ttagtgaaat gtgcatattc ttcctcccta ttttctttta
     1861 aagatttaca agatagtctt ctttataata atgttcctac atcaattttc tttgcatctg
     1921 gtactatttg tataaagcat ttaacatctt ttgatattag ctctctaaat atttcttttt
     1981 cttcatctga cacagatata tttttataaa aactttttct accaagccct gctcccatac
     2041 ctccaacatt caattccttt aaatctaccc cgctatttac taaacctaag acagttttag
     2101 ggtatttgac caatactatt aaattttcat ctccattatg tgattttaag acttcagcac
     2161 ctgattctac atcatgtact tcaaccttaa cagttgatgg agctgccatt tgtaaaactt
     2221 gaactataaa tgggtccttt actactaaat catccacgat tactatcctt tttgctgatg
     2281 taatcttaca ccaagcagta ataacttgcc catgtattaa tctatcatca attcttgtta
     2341 atgctatatt actcataatt attcctccag atttttaatt tattttacaa ctttaaaaca
     2401 gttttaacat ctttgattcc tgatatccca acttcctcac ataaattctt caagtctttt
     2461 aacttcatag tatctctgtt taaaaataac tctaaaagca taggtaaatt tacacctgtc
     2521 aaacattcta actcacatac cttagcaaat ttatttatta taatagcaga tgtattaaat
     2581 ggagttccgc cataaaaatc aagcaatact aaaacccctt catccttata tttctcaatt
     2641 ccatcttcta actttctact aaactcatct atgctgtcac catggtttaa tcctaaagtt
     2701 tctacatttt cctgtttgcc tactattaat tcagcacttt ctaacattgc tttagccata
     2761 tttccatgtg tggctataat tattcctgcc atatgaatca tacctttctt aacctttttt
     2821 atatggatta ttatttagta ctctaatcta attatctata ttaatcatta tcttaccaaa
     2881 gaaaatatcc cttttgtata ctttttcaaa ataagctggt acttcttcta aatttattct
     2941 atgtgttact aatttttcaa cattcatgtc acccttttgc atatgataca atccagcact
     3001 ccattctttt cctgggaatg gaaaggagtt tccaaaccaa gttcccttta cagttaattc
     3061 acttcttact atcttttcaa attgctctct agtcaaagct acatccccat atggtacacc
     3121 tgcatacaat actgtacctc cctttttagc tagcaacagt acttgaccac atgtcagtgg
     3181 agtaccagcc gattcaataa caatatctgc accatctcca tcagttaacc tttttatttc
     3241 ttctacaata ttcttttctt ttgcatttat acaaatatct gcccctaact cttttgccaa
     3301 gtctaacttc tcatcaaata catccacagc tattattttt gtagaaccaa atatttttgc
     3361 ccattgtatt gaaaataatc ctattggacc tgtaccaagt actacaacag tatctccaac
     3421 tttagcttct gacctaaaaa gaccatgtcc tgctatacat actggttcta gcgcagcggc
     3481 agtctcataa cttatctcat ctggtatttt tattaaattt ctctctttca cctttgtata
     3541 ctctgcaaaa caacctccaa gttctttatt tcctattatt gctacattat tacatcttga
     3601 atacaagcct tttttacatt catcacattc aaaacatggc atagctggac aaacagcaac
     3661 tctatctcct attttaaaac tccttacttc tttaccaacc tgtgccactt ctccagaaaa
     3721 ttcatgccct aaaatttctc caaccatatg tggacctgtc tttgaatatt ttgatatatc
     3781 agaaccacat attccagcta cttttacttt aattattaca tcatcttttt ctaatatttt
     3841 tggtacatcc acatcctcca ctcttgtgtc tcttatacca tagaatctaa ctgacttcac
     3901 tattaaccac ccctactttt tatttgagaa tatatcccta ttgtttatat gttaaatatc
     3961 taaagcaact ttcatgccaa tatatgtaag cattgtattc atgcatttta taaaattatc
     4021 attaaatgtg tgtcaaagtg tgtcaaaagt ttcttatatt aaaacttatg tgtgtcaata
     4081 taaacgacac taacatttta tattagttct cttattataa gttttataaa atgtactttt
     4141 tttgttattt ttataaaatt gttcggaaat ttcccttcta tttgtgatat aatattaaat
     4201 ataaggtatc aatataaatt ttcatgcgaa tatcagaact tttttgacac taatgcctta
     4261 ttcaatataa taatttaact ttttggaggt tgtttatgaa aaaagtgtat caaggaaaga
     4321 ctaaagatgt ttttgaatta gataatggaa attacttact taaatttaaa gacgatgtaa
     4381 ctggtaaaga tggagtattt gacccaggcg aaaatagtgt aggtctaagt atagatggaa
     4441 ttggtagagc taatttagag acatctgtta agttctttga aattctaaac aatgctggaa
     4501 ttaaaactca ttatgtaagt gctaatttag aagaagcaac tatggaagtt ctaccagcaa
     4561 aagtttttgg taatggatta gaagttattt gtcgttatag agctgttggt agtttcttac
     4621 gtcgttatgg ttcatgtgtt gaagaaggtg ctaaactaga ttgttacgta gaagcaactt
     4681 taaaagatga tgaccgttgt gaccctctta taacatctga aggtttagaa gctttaaaca
     4741 ttatgactca agctcaattt gattcaatga aaagcatgac tcaaaaaatt tctaacatag
     4801 ttcgcgatac tatagctgaa aaaggtcttg agctttatga tattaaattt gaatttggat
     4861 tctacaatga tgaagtaatc ttaatagatg aaatagcatc tggaaatatg cgtgtttata
     4921 aagatggtgt aatagttgac cctatggatt taactgctct tttattagat aaatagtata
     4981 tacatataat ttacaaatat aataaactta taaataagat aagctatgaa gtaaagactt
     5041 tttaaatgtt gattattttt aaacattttc tcgcctttaa tttcatagct tatttaaatt
     5101 aatatactct aattagtaga taatagcttt aaccctacaa ttcccaccac aataaaacct
     5161 atacatgcaa ttcttgatat actaataggc tcatttaaaa tagccatgcc tacaatagct
     5221 gtaccgacgg taccaattcc agtccatatt gcatatgaag ttccaagtgg aagatgtttt
     5281 agtgctaatg acaaaaaata aaaacttaca atcattccaa caacagtaag tatacttgga
     5341 gttaatttag aaaatccatg tgaatttttt agttgaaaag cccaaaacac ttcaaacaaa
     5401 cctgcaacaa acaaaaataa ccatttcata aattcatccc tcttttcaaa tatgtctctt
     5461 atttttccaa taaaataacc tgagaaatat tataaaatat ctcccaggtt tttgtccttc
     5521 cgtgttcaca acaaaaacta tgttgtgggt tttatctcgg accagaccaa tcattaataa
     5581 ttgcggaacc ctataaaact ctattaatta ttctatttta tctataataa tactatcaac
     5641 atatataaaa aaagtcaata tatgggttcc atatataata aaaataactt ttatatacct
     5701 tttaatattc ttattcactt ctctccatac ccatttgggt caatctaaga atatctaatt
     5761 tttatttaat atgttataat aacataaaaa tattgaaagg agtaatttct atgaatttct
     5821 ataaaattgc agtatgtcag atgattacta cagaaaataa aattgaaaat atcaatcatg
     5881 ctgtagatat ggtaacagaa gctgccatca atggatctaa aattgtagtt ttgccagaaa
     5941 tgtttaactg tccatatgaa aataaatatt ttcctaaatt tgctgaagaa tatccaggtg
     6001 aaacaacaac aatattgagt aaattagctg agaaacatgg aatttatcta gtttctggta
     6061 gtattcctga gttagaagat ggaaaaatct ataatacttg ctatgtattt gataaaaatg
     6121 gagctctaat tggaaaacat cgtaaaatgc acttatttga cattgaagtt acaggaaaag
     6181 ttagttttaa agaatcagat actcttacag ctggaaatga tgtcactgta atagataccg
     6241 aatatggaaa agttggtata gctatttgct atgatattcg tttccctgag ttatcacgtt
     6301 taatggctct taaaggtgct gaaatcgtta tcttacctgc tgcatttaat atgactactg
     6361 gtcccgccca ttgggagtta tctataagaa tgcgtgcttt agataatcag atattctatg
     6421 ttggtgctgc acctgctaga aatatgaatg cttcttatat agcttttgga aattcaagaa
     6481 tttcagaccc ttggggaaga ataattgctc aagctgatga aaaagaatgt attatttatg
     6541 ctgacattga tagagattta attcctgaca taagacaaca gttaccactt cttaagcaca
     6601 gaagaactga tttatatgaa cttaatactt tgaaataaaa cagaacataa ccccataaat
     6661 cgtaaattaa gtgttaaaaa aatttatggg gttctcatta atttgattta aaattaattt
     6721 cataaaaata atgctaaaat taatttaatt aaataatact aataattact aatgattatg
     6781 ctaattatca gcatttacta atttaatcac tattagttat ttcttttatt aaatatcttt
     6841 acttttttac ttattatgtc ttctagcttt acatttggat tatggtattt ctttctattt
     6901 ttagtcacat ctttctattg aattacttgc ttaaaacacc aatgcacaca tgccagataa
     6961 tgttcacaat tatgtagaaa tcttgctcta ccttcttcaa tgttgatatt atctctccta
     7021 gttgatatta tctttcctaa aatttctttt aattaaaaaa caacattagt tgatatatca
     7081 agtatatttt aatcaactga aaaaaacaat aataattgat atatcaacta attaatgtag
     7141 attaattcat ttttataatt tatatacttt ttaattaatc taccttattt aattaaaatc
     7201 cttcctttct atttatccat tttcaactta aattataaga tttcatcagc tatatttttg
     7261 cata
//
LOCUS       DAEPXW010000147         7147 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.151, whole genome shotgun sequence.
ACCESSION   DAEPXW010000147 DAEPXW010000000
VERSION     DAEPXW010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7147
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.151"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            17..877
                     /locus_tag="KRM55_003410"
     CDS             17..877
                     /locus_tag="KRM55_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1595601.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            1313..1879
                     /locus_tag="KRM55_003411"
     CDS             1313..1879
                     /locus_tag="KRM55_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1595602.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            1919..2500
                     /locus_tag="KRM55_003412"
     CDS             1919..2500
                     /locus_tag="KRM55_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1595603.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(2557..3474)
                     /locus_tag="KRM55_003413"
     CDS             complement(2557..3474)
                     /locus_tag="KRM55_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1595604.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            3604..5235
                     /locus_tag="KRM55_003414"
     CDS             3604..5235
                     /locus_tag="KRM55_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1595605.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            5238..6185
                     /locus_tag="KRM55_003415"
     CDS             5238..6185
                     /locus_tag="KRM55_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBH1595606.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(6470..6733)
                     /locus_tag="KRM55_003416"
     CDS             complement(6470..6733)
                     /locus_tag="KRM55_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBH1595607.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(6832..7077)
                     /locus_tag="KRM55_003417"
     CDS             complement(6832..7077)
                     /locus_tag="KRM55_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595608.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         2584 a          945 c         1150 g         2468 t
ORIGIN      
        1 ctatatataa ggagtgatgt tattgaaaaa agatagaata actttttcag aaattttaat
       61 attaattgta ggctgtatat taatggccat ttctcttaac ttatttttta atccacatgc
      121 aatcgctgct ggtggtataa caggacttgg agttgtttta aattcattat tcggtgtaga
      181 actttggatt gtcaatttac ttttaaatgt tccattattc atatttgctt acaaaatact
      241 ttcaaaaaaa gattgtttta aaacggtttt aggaataatt tttcttacca tagcacttaa
      301 gcttactgca aatatggcta cattagatat aacaaatgat atgtatcttg caattatatc
      361 tggttctatt ttaatgggag ttggtcaagg acttattttt agaataaatg gctctacagg
      421 tggaactgat ttaatggcac tcctactaaa taaatatttt cctacattta gtatacctgt
      481 tttaatgggt attgtagact gcgttgtagt tgttttatca ggtatagtaa atagacaggt
      541 tgaaattgca ctttattcaa ctgtggcttt atacatttta gtaaaagtta gtgacttgct
      601 tattgaagga tttaattatt ccaaatcatt cactattata tctgaccttt caaaagatat
      661 aagtaaaaaa ataatggaag atttagatag aggtgcaact attctaaaag gagaaggtgc
      721 atatactgga gaaaataaaa atgtactttt agtagtagtt gaaaagaaag aagttgtcga
      781 attaaaaaaa ttagtaaaaa atgtcgaccc taatgctttt attataatta cagatataca
      841 tgaagcttta ggtaatggat ttaaaaaaat agaataacta acaaataaat agcaagtata
      901 attaacatat acaaattcaa ctttttatat gttatattat acttgctatt tatatattat
      961 aattgttgtt tttaagataa aaattaaatg tatcaattat tgttttatac aagtatttcc
     1021 aaatccgttc tcatttagat agtatgctta gaaattttag aattattgag tctaacttta
     1081 ttacttactt cactttataa caatcaaata caaatttaaa tattataaaa ctacaaaata
     1141 atttaaagca tataatgtca atatgtttaa attataaaat attcatgtag ttatataata
     1201 aataatttat aaatatagcc aacttagcct aaatacgtat ataatatagc taatatggtt
     1261 cttatacttg ataccatcaa taaaactaaa aatataaaaa ggagaactta aaatgagtgt
     1321 tagtttacaa aaaggacaaa gagttagctt agtaaaagat aataatcctg taaaaaatct
     1381 agtagtaggc ttaggatggg atatgaataa attgggtaaa aaaaattatg acctagatgc
     1441 atttgcaata gcattgacta accaagataa aatgaatgtt agaggtgact tggtttattt
     1501 tggaaatctt aaacaccctt ctaaagctat tatacacact ggagataact taactggaaa
     1561 aggtgaaggt gatgatgaac aaataattgt taatttagaa gacatacctg aatatgtaca
     1621 taaaatagtt tttggagttt ctatatacaa agctaaaaaa agagaccagg attttggtca
     1681 aatgaacaac tcttttataa gattaattga ttcaaattcc aagcaagaat tatttaaata
     1741 taatcttcaa gaagactttt ctggtaaagt aacagttttg gcaggagaaa tttatcgtag
     1801 aaatgaagaa tggaaattta atgctttagg aattggtcaa aatgaagagc ttcgtgaatt
     1861 aattaataca tataagtaat aattacaata aaaaatttat aatgaggagt tggtttaaat
     1921 gggtataact ttagcaaaag gacaaaaagt aagtttaaca aaaagtaacc ctggtctaaa
     1981 aaaagtaata gtaggactag gatgggatat taataaatat gatggtggct ttgatttcga
     2041 tttagatgcc tctgcatttt taactggaac tgatggaaaa gtaacgaatg atggagactt
     2101 tatattctat aataatttaa aacacgcttc tggagctgtt gaatatatgg gtgataatag
     2161 aacaggtgtt ggtgatggtg atgatgaaca aataaatgta gacttatcta aaatacctca
     2221 aaatattgct aaaatatcat ttagtgttac tataaatgaa gcaattacaa gaagacaaaa
     2281 tttcggacaa gttgaaaatt catatataag aatatataat gaagaaacta atgaggaact
     2341 tattaaatat gaattgggtg aagattttag catagaaaca gcaatagttg tggcagaact
     2401 atatagacat aatggagagt ggaaatttaa tgctttaggt tctggatttg aggatggact
     2461 tgcaggattg tgtaaaaatt ttggcgttaa tataggctaa tatatctaaa taaaaataag
     2521 agtatattga tatactctta tttttattta gatatattat aaactgttta cacttctact
     2581 cttctttctc gcttgttttt tcccatattc tactgaaata tcaaaaaatg ctgaaatatt
     2641 ttctgtaaaa aacttgcttc tatgatatgc aatatcaaat gtcctatgta aattaatacc
     2701 ttcaatatca caagcccaca aaagatgctt ttttaaataa tcctcaataa gtaattcgga
     2761 tataactgca atgccaaaat tatctacaac tgctcttaat atagcttcag agttataaca
     2821 tgaccatcta atattcattg ggatttttaa ttcttttaat tgcttttcta attgtgctct
     2881 tgtaccactt cccaattcac gcataattaa tggttgattt gaaagttctg aaacttttat
     2941 agagtctctt ttataaaact catgcttgtg tgaacatata agtacaagat tatcattaat
     3001 aatgcttttt gtaacaatat ctgggtgctt aatttttcct tctacaatcg caatatctaa
     3061 ttcactatta agtaattttt ttgcaatcag tcttgtatct tctacaaata cttcaggttc
     3121 tataagagga tttaccttgt ataattctaa cattattgga cttattacac atgtaccaac
     3181 agttactgtt gccccaactc ttatacggat attttttgca caatgcttca tacaatcatt
     3241 catttcttca tttacagcta aaagatgcct cccatatcca agaagttttt tccctgcctc
     3301 agttaaatat aatttttttg aaattctatc aaatagctta acaccatact ctttttctat
     3361 ttctgaaata gcttggctaa ctgatgactg ggtaatatac atatttcttg ctacttcact
     3421 cattttacca cattcagcaa ccttaacaaa gatttcaaga ctacgaattg tcatattatc
     3481 acaaccttag caaacattag taaatgctta tgattttatt aatattttag tattttacaa
     3541 atatattgtc aagaagtata attttattat agagttataa agtagattgg agtgtgatat
     3601 attgtgaaag tattaattat aggtggagtt gctgctggaa caaaaactgc tgcaaaaata
     3661 aaacgtgaaa tgggtgataa ttgctctgtt acaatactaa ataaaggtga tgatatttct
     3721 tatgcaggtt gtggtcttcc atattacgtt ggtaagataa ttgaagataa atcatcttta
     3781 atcgtaaata cacctgaaag tttttctaaa ctaacaggag cagaagttcg ttgtggagtt
     3841 gaagttacat ctattgatag aaatgcaaaa caagtaactt tgaaaacgct ttcaacagga
     3901 gaaaaagaaa atctaagcta tgacaaactt gtaattgcta caggggcaga cccaataaaa
     3961 ccaccaatac ctggaataga tttacctgga gtattcttta tgcgtactcc aaatgatgct
     4021 ataaaactaa gagattctat cgaaaacggt attaagagag ctgttgttat tggtggaggt
     4081 ttcattggtc ttgaaattgc tgaaaatctt tctgcaatgg gtatacgtgt aagtgttgtt
     4141 gatatggctg aacatgttat gcctggattt gatactgatt ttgctgaata cgttgaaaat
     4201 catatggctg ataaaggcat aatgattttt acaggtgacc aggttgtagg tattgaaggt
     4261 gaaaataaag ttgaaaaact tcgtactaaa aatagagcta ttaaaacaga tttagtggtt
     4321 atgtcagttg gaatccgtcc taacacaggt tttctaaaag acacaggttt agaatttgcc
     4381 cctaataata caattattgc agatgaatat atgcttacaa atgacaaaga tatatacgta
     4441 gttggagact gtgcttttgt aaaaaattct ttaacaaata aacctacatg gtcacctatg
     4501 gggtcatctg caaatcatga gggtagaatt tgcgcacaaa atatatctgg aaaatctaaa
     4561 acttacaatg gtgttcttgg aacaacagta gtaaaattac ctgagctcaa tgcaggaaaa
     4621 acaggtctaa gtaaagaaat agctgaaaaa gaaggttata atgtttgctc tgtaaccata
     4681 gctactgatg ataaagctca ttattatcca ggtgcatcta attttattat aagaatggtt
     4741 gctgaaaaaa atactagaaa attattaggt gttcaagtta tgggacctgg agcggttgat
     4801 aaaatagtag atattgctgc tactgcaata actttaggcg ctgaccttta ttcattagaa
     4861 agtatggacc ttgcatatgc accacctttt tcaacagcta ttcacccttt tgtagtggca
     4921 gtaaatgttt tacaaaataa acttaatgga gaacttgata gtgttttact tgacgaaatt
     4981 gaggattttg acagttggac taaacttgat gtttcaaaag ctccttctat tcctagttta
     5041 cgttatattc ctgttggtga aattaatgga gaaattgaag gccttgctaa ggatgaaaaa
     5101 attcttctta tatgtgctaa aggtaaaaat agctatatgg cgcaaaatcg cttaagacgc
     5161 tttggctata caaatacgaa agttcttgaa ggtggaatac tattttatcc aaatcttaag
     5221 gtaatggagg agtaaatatg agtaatgtta cagcagaaca aaaaaaggaa gtaaaaggta
     5281 gaggttttct accaagcagg gatggagaac attttgcagc acgtataata actgtaaatg
     5341 gtgtaataaa tgcatcacaa gcaaaaaaaa ttgcagaagc tgctgaaaaa ttcggaaacg
     5401 gtcagttagc atttactact agactaacag tagaattacc tggtgtaaaa tttgaagata
     5461 ttgaagctct aagtgaattt attgctagcg aaaatctaat aacaggtgga actggatcaa
     5521 gggttcgtcc tgttgtggct tgtaaaggta ctgtttgtgt tcatggtcta gctgatacac
     5581 aggcacttgc tgctgaaata cacgaagaat tttacaaaaa ttggtatgat gtaaaactac
     5641 ctcataagtt caaaattggt gttggtggat gccctaataa ctgtattaaa cctgacctaa
     5701 acgatcttgg aattgttggt caacgtgtac ctgactatga ttcagagctt tgtgttggtt
     5761 gtaaaaaatg tgctgttgta gaggtctgtc ctgttaaagc agctaaatta acagataaag
     5821 gtaaacttga aatagatagt aatctatgta ataactgtgg taagtgtata gaaagttgta
     5881 attttgatag tattgaagaa aaagaatctg gttataaagt ctatatagga gggaaatggg
     5941 gaaaatcagt tcgtcctgga acacagattg atagattatt ttcaaaagag gaacttatga
     6001 ctttaattga aaaagcaatt cttttattta gagaacaggg taacacaggt gaacgttttg
     6061 gaataactat cgatagaatc ggtgctgata aatttataga aatgctttta tcagatgaag
     6121 ttttggaaag aaaagaagag atactagagg ctcttttaca ccttacaggt ggagctgtat
     6181 gctaacaata aatattttaa ttgtacagat aacctatgga aaaaatttta gttaagaata
     6241 attaaaattc tatatatgat atatgataaa tgaggctatc tcaaaacaca gatacgcctc
     6301 tttttcattg ttgaaatgat aaagtatatt tgagttcata taaaaaagag tgtctcgtga
     6361 attataaaat tcattttgag gcacccacat tattttataa taattgctta ttaattttat
     6421 tttaactata taaaatgtac aaaaagtaag aatatccaat attctaaaat taattttgaa
     6481 ttgtattgat tgaaaagttt actattccac tatttccgtc ttgatttact actagatacc
     6541 atgttccagt attaggaact ctcattctac atggattttt ctttgcaaat ccaccatagt
     6601 aatcataatt tctttgattt ttaaatttca cataatttat atggtctaac aatattacat
     6661 tggcttgttt ctctaaattt acctctacaa tatccccttt ttttaagttc atcttactat
     6721 aactatattc cattgaatta ctcctccagt atcgaataat ctttgttatt tactcatctc
     6781 aaatatgtaa aaattcattt aaaatattac aaatactata taattagact attatccagt
     6841 tttaacctta tttactacaa tccaaaggtt attaaaaata ttattggcaa caacttctcc
     6901 atcccataca actctttctt ctttattttc taataaagca tagtacccag agtcagaact
     6961 ttcatcttta tagactgtaa cataaaactc ttcatcacta tattcaggta tatttttaaa
     7021 gtcttcagat attttacatg ttaatatata accttctaat tcttcatcta taaacaaagc
     7081 aattcctcca atctctatat ttttactaat tataccatat tatgtcataa actttttatt
     7141 ttattac
//
LOCUS       DAEPXW010000148         7116 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.152, whole genome shotgun sequence.
ACCESSION   DAEPXW010000148 DAEPXW010000000
VERSION     DAEPXW010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7116
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.152"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            51..431
                     /locus_tag="KRM55_003418"
     CDS             51..431
                     /locus_tag="KRM55_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1595609.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            556..756
                     /locus_tag="KRM55_003419"
     CDS             556..756
                     /locus_tag="KRM55_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595610.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            952..1680
                     /locus_tag="KRM55_003420"
     CDS             952..1680
                     /locus_tag="KRM55_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1595611.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            1702..2619
                     /locus_tag="KRM55_003421"
     CDS             1702..2619
                     /locus_tag="KRM55_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBH1595612.1"
                     /translation="MNKIDLNLLERVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            2761..3945
                     /locus_tag="KRM55_003422"
     CDS             2761..3945
                     /locus_tag="KRM55_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1595613.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            4052..4240
                     /locus_tag="KRM55_003423"
     CDS             4052..4240
                     /locus_tag="KRM55_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH1595614.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            4389..5039
                     /locus_tag="KRM55_003424"
     CDS             4389..5039
                     /locus_tag="KRM55_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1595615.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            5142..6080
                     /locus_tag="KRM55_003425"
     CDS             5142..6080
                     /locus_tag="KRM55_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH1595616.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            6106..6957
                     /locus_tag="KRM55_003426"
     CDS             6106..6957
                     /locus_tag="KRM55_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1595617.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDTIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
BASE COUNT         2944 a          668 c         1275 g         2229 t
ORIGIN      
        1 aaatataaaa aatattaggt atttatttaa taataaaggt gggtattgtt atgataaata
       61 aaataggaaa aataactctc tatgtaaata atcaagagga tgcaaagtta ttttggacag
      121 aaaaattgaa ctttgtagta acttatgaaa aggaaatggg tccaaatatg aaatgggtgg
      181 aagtagcacc aagtaaaaat gaatttacaa catttgtgtt gtatgataaa aatctaatga
      241 tgaagcaaaa caaagagata aatgtatctc atccatcaat aattttaagt acaagagata
      301 ttaatggaac ttatgaacaa atggcaaata acgaggttga ggttggggaa ttaatggaga
      361 tgccatatgg aaggatgttt tcttttaaag accaagatgg aaatgattat ttggtcagag
      421 aggataaata attttacaaa gtattaaatt tactcaatat ctgatataat tagagacaat
      481 aattattata aactagtcta ggattagaat tatataatta aaaattaagt gtaaattttg
      541 agtagaggtg ataaaatgtt taagaaaatg gcagtactaa aagatatagc aactaaaata
      601 ggtcgtaaaa aagcgtatga actattagaa atggttgaag gtaatgatgc ctttgtagct
      661 gaggtaaaga taaaaaagaa tggaatagaa tctaaaaaag aagaaattat gttaaaagat
      721 aatcaaaaaa taatattaga gtatatagaa ggttaaattt taaatacata taagttgata
      781 tactaaattt ctgagatgag tttacataaa actcatcttt tttacttttc aataactttg
      841 ttttattatt taatatacat tttatctcct tagagttgct gatatataaa aattactgat
      901 ataataaaag aatggatatt aatgtaatat tttatagaaa agaggggtat tatgcttgaa
      961 ataaaaaatc tttcctttaa tgttgagtct aacaatgagg aactaggaat aataaatgat
     1021 gttagccttt catttgagag gggaaaactt attgttatca caggtccaaa tggtggagga
     1081 aaatctacaa ttgctaagct tattatggga attgaaaaag ctacgagtgg tcagataatt
     1141 ttagatggag aagatataac aaatcttagt attacagaaa gagcaaaaaa aggaatagga
     1201 tacgcatttc aacaaccacc aagaataaaa ggtatgacag ttgaaaattt acttacactt
     1261 gctcatggaa aaccattgtc tactgatgta tgttgccaat accttacaga tgttggattg
     1321 tgttcaaaag actatttaaa tcgtgaagtt gataactctc tttctggagg ggaaatgaaa
     1381 agaattgaga tagcaactct ttttgctaga gatttaaagg tttctatatt tgatgaacct
     1441 gaagcaggga tagacctttg gagctttgga aaactcaatg aaagttttaa gaaaatacat
     1501 gaagagtcta atcagactat aatcataatt tctcaccaag aaagaatatt agagttagct
     1561 gatgaaataa ttgttctaca agatggttca gtaaaaagcc atggaacaaa agaggctata
     1621 ttacctgaaa tcatgtgtca agttaattca agttgtgaat taatgaaaga catgaattaa
     1681 ttagaaagga aggcaaatta aatgaacaaa atagatttaa atcttttaga aagagttgct
     1741 gaacttcgtg gaactccatt aggagcatac aatatacgta aaaatgggca aggagtagag
     1801 agacattcaa ctgaaaatgt aactataatt cctaaaactg ataaacctgg aatagatatt
     1861 atagtaaagc caaatacaaa aggagaaaat gtacatatac cagtaatagt aacagaggct
     1921 ggtgtacagg atatggtata taatgatttt gaaattggag aaaatgcaga tgttgttata
     1981 attgctgggt gtggtataca taactgtggt tgtgatgata gtgaacataa tggtatacat
     2041 agatttttct tacgtaaagg agctcgccta aaatatgtag aaaaacatta tggtgaaggt
     2101 gatggagaag gaaagagaat tttaaatcca gttactattg tcaatatgga tgaggattca
     2161 tattgtgaaa tggaaacaat tcaaattaag ggtgtagatt caactaaaag agaaatggat
     2221 gcaaacctag gtaaaggagc taaaatagtt gtatttgaga aattattaac tcatggtaat
     2281 caagttgcag aatctaatat gaaggttatc ttagagggtg aaaactcttc tgctcaagta
     2341 gtttctcgta cagttgggca agataattct aagcaaaagt ttaatccttg tgttattggg
     2401 gattcccttt gttctgcaca tgttcaatgt gattcaataa ttatgggaaa ttctcaaatt
     2461 agtgctatac ctgaaattgc tgcaaatcat ccagatgctc ttttagtaca tgaagcagct
     2521 attggaaaga ttgcaggaga ccaaatacta aagatgatga cattaggtct tactgaagaa
     2581 gaagccgagc aacaaatact taattgcttc ttaaagtaaa ttaaagattt tatttaattt
     2641 aatataatta atatagtata atatagtgaa taagtctaaa atatttttat ttttaggctt
     2701 attttcttta tgtaagaaaa gctattagag aaattatatt gtaattagga tgtggaataa
     2761 atgaaaaatt tacttataag aaatgggaca ataatatctc caacagatgg tatcaaattt
     2821 gaaaaaagag atatcttggt tttacatggg aaaatatatg ctattggatt gaaccttaaa
     2881 gagaaaataa gaaaagaaaa attacttaca aataaagagt tcgagataat aaatgccgat
     2941 aatatgtata tttccccagg atttatagat gttcacaccc attgttataa gagaaaatta
     3001 cctacaggta tggattctga ttcaattgga attgaaaaag gttctacagt tatatttgat
     3061 gcaggtacag ctggtccttc aaactactat gattttaaaa aaaagtatat ggatgagtgt
     3121 aaaacagaag tatattcttt tttaaatgtt acaaatgagg gactaaatat attgaatgaa
     3181 tcaacttctt tagatgttat aaattttgac aaggttgagt cagttgtaga aaaaaatata
     3241 gaaaagataa agggtataaa agtaaaagcg agtaaatttc aatctaatga aagtggtata
     3301 gatataatta agaaatcaaa gcaagttgct aaaaaattaa atttaccctt agtggtatat
     3361 ataggagagt atccatcata tatagatgaa gtaatgaata ttttgggaaa aggagatgtg
     3421 gttacaccag tatatggaaa tagtacaaat ggaatcctta aagaatctgg cacattaaga
     3481 aaatcagtaa taaatgcaaa gaatagagga gtattgtttg atgtatgtca tggagtggac
     3541 caatttgatt ttaaagtttt taaaaaagca ataaagcaag gtttagagcc tgacctaata
     3601 agtactgata tgcatataaa aaacatgaaa gacgtaaact attctctttt aaatgttata
     3661 aataaaatta tggaacttgg gatatcccta gaaaagtgta tagaaaaagt aactgaatac
     3721 ccaacaaaga ttttcgattt acatggaaat aaaggcagaa taaagattgg tggagaaggt
     3781 gattttacaa tattcacaat ggaggagtgt aatgatatta taaaagacta caataataat
     3841 gaacttgttt taaataaaaa attaagattg caatatactg taaaatcatg gatgaaaagc
     3901 agtgaagttt atagacatgg atacgaaaat actataataa actaaacaat agtgataaaa
     3961 taataaatat atgtttaaat tggtatatat tggataaata tctaaggaaa caacaattaa
     4021 aaaataataa ttttagggga ggtattttag tatgaaagca tttgttgata aggatgtatg
     4081 tgtagcttgt ggagcatgta taggaacatg tccagacgtt tttagtatga gcgatgaagg
     4141 gcattcagta gcaattgaag gagaaatacc agcagattta caagatttat gtaaagaagc
     4201 cgaagaagga tgtccagttt cagctataac agttaaatag agctgtttaa atttattttt
     4261 aaaataaata tataagattt aattggtact taagctatag tattagaaat ttctattact
     4321 atagcttttt aaaatagata aacttaatat ataagatatt actttttaca aatatggagg
     4381 actgaaatat gaaaaaaaat tatgaaatag tattattcga tttagatgga acacttacag
     4441 accctaaaga aggaataaca aagtctattc agtattcttt aaatagtttt ggcataaaag
     4501 aagatttgga aaacttagac caatttatag gaccaccatt acatgatact ttcaaggagt
     4561 attataaatt tgaagataaa aaagctaaag aagctgttga aaagtataga gaatattttg
     4621 ctgataaagg gatatttgaa aataaaattt atgagaatat gaaagagata ttagaaatgc
     4681 tctataaaaa tggtaaaata ttattagtag caacttctaa gccaacagtt tttgcagaaa
     4741 ctatacttag atattttgat atagatagat attttaaata tatagcaggt agcaatcttg
     4801 atggtacaag agtgaataaa aatgaagtta tacaatatgt actagaccta tgtaacgtaa
     4861 aagataaaga taaagttatt atggttggag atagaaagta tgacataatt ggagctaaaa
     4921 aaataggtat agattctatt ggagtattgt atgggtatgg ttcttttgaa gagattagtg
     4981 aaagtgaacc tacttatatt gtcgaaaatg tagagtctat aaaagatatt ttgttataaa
     5041 tatcttttat agacaaaaat attacaaaat ggtgtcgcat atttaaaaat atgatattat
     5101 agttaaggaa gtcatttaaa aaagaggagg atgcacttaa aatgaaatct attttaatta
     5161 tgggtggaag cgacttcata ggttctgcac ttgctaagcg cttgattaaa tgtgggtatc
     5221 aaattgatat acttacaaat ggtaaaaagg aaatagatta taatggtttt aaagaacatc
     5281 taatttgtga tagaaaagtt cgaaaagata tggaaaacat tatcacagga agaaaatatg
     5341 attacatata tgatatgaca gcatatacaa aagaagatgt aagtaatctg attgatttta
     5401 taagcatgga taacttaaaa aagtatatag tattgtcagc aggagcagta tataaagata
     5461 gtggaagaaa tataaaagaa gaaaatgaga aaggtgaaaa tgaaaactgg ggaaaatatg
     5521 ggttaaataa aaaagaggct gaagatttta ttataaatag ccctatacca tatataatta
     5581 ttagaccaac ttacatatat ggtgaaaata ataatttata tagagagtat tatttctttg
     5641 aaaaaataga aaaaaatgaa aagataccag taccaaaagg aaaacaagtt agtaatcaat
     5701 ttatatatat tggggatttg gtaaaggtat tggaaagcat aatgaaaaat cctcatgtaa
     5761 gagaggccta taatgtgaca aatccacagt taatttcttg ggatgacctt atatatacat
     5821 gtggagaaat tattggcaaa gaacctataa taaaatatgt agatatggaa aaagtagagt
     5881 ttagagaaag aacgtatttc ccatttagaa atatagactt taatcttgat ataaataagc
     5941 ttattgaaca tgggctttat ataccaaacg tgttactaaa agaaggtctt acagcaacat
     6001 ataaatggtt ttcagcaaat aagccaaaaa tgcatgacag aaaaatgaac aaagttgagt
     6061 ctgtaatgca aatagtttaa aaaaataaat aagtaggtag atattttgaa ctcaaaaatt
     6121 aagtattttt taaaattttt tatcttaata tttattttga tttttatata ctcagttgcg
     6181 atagagccga gtctattaat tgtgaaaaaa tataatataa gtgaaaatgg agcattgata
     6241 aaaaatgata caattgagag taaatctgaa agtgtaaaag tagttcaaat ttcagatact
     6301 caaataggta gtttttattc aactaagaat ctcaaaaaag tagctaataa gattaacact
     6361 ttgaatccag atataatagt atttactggt gatttaattg attactccaa taaaaatcca
     6421 agtgtagatg aaattacaac tattttatca agtatgaatg ctaggttggg aaaattttca
     6481 gtatttggca atcatgatta tatgtataaa cttcctaggt attataggca gattatgaaa
     6541 aattccaact tcaatctttt agtaaatgaa aataaaaaaa taaaattaaa agatgataaa
     6601 tatattaata tattaggtgt tgatgaaata ttaaatggaa atcctaatat aaaatatctg
     6661 gagagtcaaa tagataataa aagttttaat ttattgttag cacatgaacc agatttagta
     6721 gatatgctta gtaaagatac aatgaattta gttctatctg ggcatagtca tggtggtcaa
     6781 ataagattac ctattaaggg agcattagtt actcctccat atggaaggaa atatactaaa
     6841 gggttttatg atataaatgg aaatcattta tatgtgagtt cgggtcttgg aagtacaaag
     6901 ttaccattta gattttttaa tataccagag ataatagaat ttaatattat aatctaacat
     6961 aaaatattta gaaaatataa ttttgctttt tataatatgt agatgtatat actgtaaaaa
     7021 tggattaaac cagtagattg aatgaattaa tagattaaat taatatataa aatatttaag
     7081 ttataattaa tgtattagac aaaataaata ctatta
//
LOCUS       DAEPXW010000149         7112 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.153, whole genome shotgun sequence.
ACCESSION   DAEPXW010000149 DAEPXW010000000
VERSION     DAEPXW010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7112
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.153"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(96..183)
                     /locus_tag="KRM55_003427"
     tRNA            complement(96..183)
                     /locus_tag="KRM55_003427"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(147..149),aa:Leu,seq:caa)
     gene            335..2983
                     /gene="polA"
                     /locus_tag="KRM55_003428"
     CDS             335..2983
                     /gene="polA"
                     /locus_tag="KRM55_003428"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBH1595618.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            2992..3594
                     /locus_tag="KRM55_003429"
     CDS             2992..3594
                     /locus_tag="KRM55_003429"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBH1595619.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            3587..4141
                     /locus_tag="KRM55_003430"
     CDS             3587..4141
                     /locus_tag="KRM55_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH1595620.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            4141..5856
                     /locus_tag="KRM55_003431"
     CDS             4141..5856
                     /locus_tag="KRM55_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1595621.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            5929..6141
                     /locus_tag="KRM55_003432"
     CDS             5929..6141
                     /locus_tag="KRM55_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBH1595622.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            6342..6941
                     /locus_tag="KRM55_003433"
     CDS             6342..6941
                     /locus_tag="KRM55_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595623.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
BASE COUNT         3053 a          684 c         1267 g         2108 t
ORIGIN      
        1 aaaaagacac agtaatttca aaaaataact taaaatttaa atcaaaaata aaaaaactcc
       61 taatctattg aataaatagc tttaggagtt tttaatggtg cccgaggccg gactcgaacc
      121 ggcacggagt attagtccgg tggattttga gtccactgcg tctaccaatt ccaccactcg
      181 ggcatgtcat gtatattatt atagcaaaaa aatatattgt ttgcaacata tttaatttta
      241 atatactatt attattatgg gaatattaaa taacagtata ttggtatata atatatatgt
      301 tacaaaaata gataattttt aggagtgata taatttggaa aaaaaattaa ttataataga
      361 tggaaattca ataataaata gagcttttta tgctcttcca gaaatgaata ataaagaagg
      421 gctaaagacc aatgcaatat atggatttac aacaatgcta tttaaaatga tagatatata
      481 taaaccaaca catataagtg tagcatttga cagaaaagca cctacattta gacatttaga
      541 atataaagag tataaggctg gaagaaaggg aatgccagat gaactggcag aacaattaca
      601 gccattaaaa gaccttttag ataaatttag aataaataga ttggaaatag atggctatga
      661 ggcagatgat attataggta ctgtttctaa aaaagcagaa gaaaatggat ataaggtata
      721 catagtaact ggagacaaag atgctattca acttgcttca gacaatacaa ctactcttat
      781 aacaaaaaaa ggagttggag aagttgaaga atacaacttt aattctgtaa ttgaaaaata
      841 cgagatgact ccaacacaat ttatcgattt aaagggtctt atgggagaca agtctgataa
      901 tatacctgga gtacctggaa taggtgaaaa aacaggtata aagcttataa aagagttttc
      961 tagtatagag aatctaatag agaatacaga taagcttaaa ggtagtgtaa aaaagaaaat
     1021 agaggaaaac aaagaaatag ctattcaaag taaaagactt gcaacaatta taagagatgt
     1081 gccaatagaa gtggatttag atagtatgat ttttggcgat tatgataaag atgaactttt
     1141 agataaattt agatactttg gatttacaag tctcttatca agattagttg atttggtcga
     1201 ttcagatgac acagaacacg tagaagaaaa aatagaaata ttaaaattaa aagatataga
     1261 aaaatttata gatgaagtaa acaaaaaagg acaagttatt ttaaaaactg ttagaggaca
     1321 aggtaatata cttgaaaaaa atataatata tatttttata agtgtagatg gagaaaaaat
     1381 atattatgta gattcaaatg aagtgtcaaa gttagatagt atattttcaa ataatgaaat
     1441 taaaaagtat ggatataatt taaaagatga ttatatatct ttaaaaccat ataatataaa
     1501 cttagaaaat atgtattttg atataacaat agctgagtac ttaatagatt caacttcatc
     1561 tacctcatat gattgtagtg caatagctat gaagtattta tcaaaaaagg ttaaatcaaa
     1621 agaagaatta ttaggaaagg gtgttaaatc taaaaactat gaggatttag aatttgagga
     1681 tttagcagag tatatgggtc aaataatatg cacagttaaa gaaacagttc ctatgatgga
     1741 aagaagtcta atggatatga gtatggatgg tcttttttat catgtagaga tgcctttagt
     1801 agaagtctta ggtcatatgg agtatgaagg tataaaagta gacaaaagta tattggatga
     1861 attgagtgta gagtttaaag aaataatagc tacattagaa aaggaaattt atgaattatc
     1921 aggagagcca ttcaatataa attcaccaaa acaattgggt gttatattat ttgaaaaatt
     1981 agagcttcca ataattaaaa aaactaaaac tggatattca actaatgcag atgttttaga
     2041 aaaattaaga gataagcatc caataataga taagataact gagtatagac aaatagtaaa
     2101 gttaaattct acttacgttg aaggactttt aaatataata aatccagaaa gtaatagaat
     2161 acattcatca tttaatcaaa ctataacgac tacaggaaga atttcatcta cagaaccaaa
     2221 tcttcaaaat atacctataa aaatggaaat gggtagaaaa ataagaaaag tgtttattgc
     2281 agatgataac tgtaagttgg ttgatgccga ttactcacaa gtagagctaa gagttcttgc
     2341 acatatgagt caggatgaaa atatgataga agcatttaaa catcatgaag atattcatac
     2401 caaaacagct tcacaagttt ttaatgttcc tatggaagat gttactagtg aattgagagg
     2461 tgcagctaaa gctgtaaact ttggtattat atatggtaaa agtgactttg gtctagctga
     2521 tgatttaaat atacctgttc caaaggcgaa agaatatatc gaaagttatt ttgctaaata
     2581 ccataaaata aaagagttta tggacacaac agtagaaaag gctagtgagg atggatatgc
     2641 tgtaacaatt ttaaacagaa gaagatatat accagaaata aagtcaagca attttatgga
     2701 aagaaataga ggaaagagat ttgcaatgaa tgcaccaata caaggaagtg cagcagatat
     2761 aataaaaatt gctatgataa atgttcataa aaaattggaa gagaacaatt tgaaatcaaa
     2821 acttatacta caagttcacg acgagttgat agttgaagca attgatgatg aaatagatat
     2881 agttaagaaa atagtaaaag aagaaatgga aaatgctgta aatatggatg ttcacttaga
     2941 tgtagattta aatgtaggta gttcttggta tgagacaaag taggtgattt tatgttgata
     3001 ttaggactta caggaggaat aggctgtgga aaaagcagcc tatcaaatat atttagaaat
     3061 cttaacattc ctatagtgga tgctgatatt atatccagga agatatttga ggataagttg
     3121 ttattggaaa aagtatttgt ccattttggg caaagtataa aaaatgatga tggaactcta
     3181 aatagaaaag ctcttgggaa aatagttttt agtgatgaag aaaaacttaa ggaattaaat
     3241 aacttgactc atccacgaat aagagaaaaa ataataagtg aaatagaaaa attgagaaaa
     3301 aaaggcgaaa atatagtagt gttagatgcg gcaatattgg tagaaagtgg ttttttagat
     3361 atggttgaca agctattagt agttacttgt aaacaagaag tacaaattag tagaatacaa
     3421 aagagagata attgcagtga gcaggaagca cttagtagga taaattcaca gatgagtcag
     3481 gaagaaaaat ccaaatatgg tgattatata atagataatt cgggaacaat aactgaatta
     3541 gaaagtaaag cacataaatt tattgagtac atgaaggaga attggcgtga atagtaagaa
     3601 agtattgatt ctatctattt ttataatctt atttggggca ctattaatgg aaagcaaagt
     3661 aatacataaa tttttatatc ctaaaaaata ttcagagtat gtagaaaagt attcgaaaga
     3721 atttaattta gatgaaaata tagtttacag tgttattaaa gccgaaagta agtttaatag
     3781 ttctgctgtt tcaaaaaagg aagcaaaagg attaatgcaa atattagaca taactagaga
     3841 ttggggagca gaggaactaa atttaaaaaa tgtggatatt ttcgacccag agactaatat
     3901 aagacttggc tgttggtatt taagtaagtt atacaaagaa tttggtaaat tagatttagt
     3961 gatagctgca tataatggtg gttcaggtaa tgtgaaaaaa tggttagaaa ataatgaata
     4021 tagtaaagat ggcgaaaatc tacatgatat accttttaag caaacttcaa aatatgtaga
     4081 aaaagtaaaa aataattacg aacattataa taagatatat ggcaagaaag gaaaaaacta
     4141 atgaagagaa taaaagtctt aacagtcgtt ttagctataa ctcttatggt agctggttgt
     4201 agtaatacta aaacaaaaca aagtagtagt gattcaagtt tacaaagtca aagttctata
     4261 gatgctaagt atataaactt aacaatggta actccaaaaa ctataaatcc tataactaat
     4321 actgataagt ctgttggtta tataatgaat ttagtttatg atagtttatt tactatagat
     4381 gagaactaca atgtaattcc tcaattagtt aaggagtata atatagctca ggatggaatg
     4441 agtatagata taaagctaaa agatgcaaag tggcatgatg gaaaaaatgt tacttcaaat
     4501 gatgtaaact atactattgg tttaattcaa aaaagtgcag atagtccata taatgaattt
     4561 actaaaaata tagcttctgt gaatattaaa tcagataaag attttacaat aaaatttaaa
     4621 gctagatatg ctttttcaat tgatagttta atttttccaa ttgtatctca aaatcattta
     4681 gattcaaaag atgtaaatga caagaataat aatatgatag gaaatgggaa atataaaata
     4741 gaatcatata cagaaagaga aggaatggtt ttatctgtaa acaaagatta ctatgaagaa
     4801 gttccaaaga ccatgaagaa cataaaagta ggtatggtgc ctaatgaaga tgcaaggaca
     4861 tctatggtta tggctcttga tagtgatata accaatgtta cattaaatga tttaagtaag
     4921 tttcaagaaa aagagtttaa tataacaaaa tatcaaggaa gagattatga gtgtgtatta
     4981 tttaattata ataatccttt tttcaaagat gttaatttta gaaaagcaat tgcacactct
     5041 atagataaag atagaattat tagtgaaggt tatatggatg atgctactcc agttaatttt
     5101 ccacttaatt caaaatcaaa atactataat agtgaaatga aggatttaga gtttaataaa
     5161 gataaggcga tagagtgtct tgctaaggta gaatatgcaa atgtaaactc agtaaatcaa
     5221 aatgacaata aagtaaaaaa tcagaaaaaa tcagctaaaa agaactcaaa gaagcttacg
     5281 ccagaagaag aagcaaaagc taaaaaagca gaagaagata gaatcaaaaa agaagctgaa
     5341 gagaaaaaaa atagagaaaa agaggaagta aagaaaagtc tttctgaaat gaacttaaag
     5401 ataatagtaa acagagataa tagtgagaga ataaaaactg caaacataat aaatgaaaac
     5461 ttaaaagcta taggaataaa tagtacagta aatcagctgt cagataagga tatggaaaat
     5521 gctcttaatt ctaaaaatta tgatttagca ttagttggat ggaaactatc aattatacca
     5581 gatgcaagta gtattatagc gagtagtgga tatactgatg ataagttaaa tggatatatg
     5641 tctgcactta caagttctac gtctgaaatt gaaacaaaaa aagcatacaa agatgtacag
     5701 acatatataa aagataatgc aacatttata agtttagctg tcagaaacaa ctatattgta
     5761 agtaatagta gattaaaagg taaaattact ccaaatgatt ttgatgtata tgagggaata
     5821 tctaatttag atataaaatc gaatgaatca aattaaatga ttaatttcta tttaaaaagt
     5881 ataaactata tgatagaata cccttatagg gtataaggag gtaattaaat gaagaagaaa
     5941 ctattagtag aaggtatgag ttgtggtcat tgtgtaaacc atcttaaaac tgcattaaca
     6001 gaagatatag atggtattga agttttagat gtagatttag aaaataagtg tgcatctgta
     6061 gatatgaaag atgatgtatc tattgaaaaa ttaaaagaag tgatagcaga attaggattt
     6121 gaactaaagg gaattgaata gaaattgata aactaaaaaa agacctctat tgggggagta
     6181 atagaggtct aaaaatgggg gagattgagt atgtttgatt ttacattact attatctccc
     6241 cttttaaatt aatatataca taaaaagtaa aaaaattttg taatgactca catttcttga
     6301 gctttttgaa tatactataa atagctaagg gagggagtat catggaatct aggggatata
     6361 aagaggattt aaaaaaaatg atacttgata tggcccacaa agaacttgag agttatgtat
     6421 cacaaaaagg agcaaaaaaa tactttgaag gtaacttgga taagattatt aataataata
     6481 taaaaaaatt caatcaaagt attggtctta atagagtata tttaaaaatg ttaaaaaagt
     6541 gtgcatatca agaaagtgta acttcaatat caaggactat aaagaaagaa gcattattta
     6601 aatcaaaaaa agagctattt gctttttcag agtacttaaa acttgatatt aacaagcgac
     6661 tttcatataa tcaaatttta agaaaaatat caagatatat atactacaat agaagttcat
     6721 atgctcaaaa atacgttgtt ttcaaaagag gagatgaaga atatctttta gaaccagaga
     6781 aaataaaaga tgaattaata tcaagctata ggtcaaagac tagagaagat atgaggtcaa
     6841 tagcaaaact tttggatata gaagtagaag atgattataa tgctgaagat attagaaaaa
     6901 aagtaataaa ttatattatt aaagaaaaac ttaaaagtta gagttttaaa gaataagttc
     6961 tgccaatttg catgattaag tataacttgg gtataaattt tttatgcatt tgaaagagct
     7021 tattcttttt ttgacatatt tttttaaata atttaccatg atttggtaat tggtcatcat
     7081 cattcaaatt tttaacttaa tatgatttaa at
//
LOCUS       DAEPXW010000150         7064 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.154, whole genome shotgun sequence.
ACCESSION   DAEPXW010000150 DAEPXW010000000
VERSION     DAEPXW010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7064
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.154"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(52..495)
                     /locus_tag="KRM55_003434"
     CDS             complement(52..495)
                     /locus_tag="KRM55_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBH1595624.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(519..1313)
                     /locus_tag="KRM55_003435"
     CDS             complement(519..1313)
                     /locus_tag="KRM55_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBH1595625.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(1878..2354)
                     /locus_tag="KRM55_003436"
     CDS             complement(1878..2354)
                     /locus_tag="KRM55_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1595626.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDDPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRIENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(2455..3624)
                     /locus_tag="KRM55_003437"
     CDS             complement(2455..3624)
                     /locus_tag="KRM55_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1595627.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKQNIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            3787..4650
                     /locus_tag="KRM55_003438"
     CDS             3787..4650
                     /locus_tag="KRM55_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBH1595628.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            4721..5314
                     /locus_tag="KRM55_003439"
     CDS             4721..5314
                     /locus_tag="KRM55_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBH1595629.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(5565..6200)
                     /locus_tag="KRM55_003440"
     CDS             complement(5565..6200)
                     /locus_tag="KRM55_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1595630.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNKVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(6280..7011)
                     /locus_tag="KRM55_003441"
     CDS             complement(6280..7011)
                     /locus_tag="KRM55_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH1595631.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
BASE COUNT         2623 a          908 c          998 g         2535 t
ORIGIN      
        1 aataatagaa atacgaaaat atgtgttcta ttaaggaatc tatctttttt attaaggttt
       61 tttcttatcc ctatcaaaaa aatccataca ttctgataaa agataagaaa gtaaagcgaa
      121 taagatttct gtacttaaag gaatcgttac tgaatccata aaggtatcaa ttatgttcat
      181 agctagaaaa gttagtataa aatcaattat aaattcgcaa agtttatata ttgagtatgg
      241 taatttgttt acatatctga atatatctaa aatagtagtg catagaaaat caattggagt
      301 ggttatacaa aaatatatta aaaagaaaat taatacagct ccaagagatt tatattcaaa
      361 tcctaagaat gataagaagc caattcctat aaccgtgaaa atacaaaaag ttataccaaa
      421 aaaaacagca aaaaataaaa atacagaaat aaattcgcct aaaggaatcc ttcttttatt
      481 acttatctta atcaactcct taatttatga tatgaaattt atataaataa taacattctt
      541 aaaaattcat aatagtcctc tgtttcaaat agtactgttt gagaatctat ttttttcata
      601 tttggataaa aagaggcctt aaaagcttta taatgttctc taaattttat ttctatctta
      661 aatttatctg gcaattttat taagtgccta gataaatctc cagataaagc ttttttgaca
      721 cctttttcaa ttttttttag tgcaaggttt ggatggattg aaattgaacc atttccaatt
      781 ccttttgaca caggaacagt gactatattt ggatttagtt tttttgcact ctcacaaagc
      841 atttcatctc cacttaaaaa tgctacagga acattataat atgcagcaat ataagcattt
      901 atagtaaatt cagatgctat ttcatcattt attttaaaat agtcataatc aatatccata
      961 gtatgagaaa gtggattacc attacaagta gctccagagt gatagccggt gaatatacat
     1021 gcatcaaagc tttcatcaat tcctgccatc ataactagtg ggtctttggt ccatcctcta
     1081 agtattttga cgttttcagg taaaatattt ggattaatat ttctaccact gtcatgtgca
     1141 tctttaacaa gtatttcatg tacaccagat tgagtagctc catcacatgc tgctgttatc
     1201 tctttactca tttgtgttct atagtgttgc gaaaattcac attcaagttt tgtttcatcc
     1261 caatttacaa taccacaagt accttctata tcagcactta aatacaattt cataatatat
     1321 acccccttat gtttattatt gatgataata acagataaca gaaaatacat aatcaataaa
     1381 gggcataaaa atattatgtc ttactattaa ctattattaa atctgtaact gaaaaataac
     1441 taaattggta taaaaaaata taacactatg tgtcatttat ttatatagtt tttatatctg
     1501 atgtttatat aaaattgtaa catataagtg gttacattta ctagtttaac atagttaaaa
     1561 tagttaggta ttatttttaa gttaaattga ttattataaa atcgcagaat aaaagaaaga
     1621 tttaatttat taaaatgcat gaaatgtttt ttcctcaaca taatgctaaa ttaaactcaa
     1681 aaagaaataa tagaaaaatc ttatgtagct tagaaagaat gtgaatgatt taaggggaaa
     1741 atagaaattt attatataat attaggctgt attatataat acagcctaat attatatgta
     1801 tatgtgacat aaaatcttgc taagtgtaaa taaaataaat gtggaaaaca agttaatgaa
     1861 atcaagaaaa aagtaattta aaattcaatt tcatcttccc aattaaattc tcctgatttt
     1921 tctacactct taggccagtg actacaccat ttaggaacgg acggattttc aatcctatca
     1981 acgcttggag tatatggctt taagtcaata acaggactat tatcattagc atcaatatat
     2041 ggtattttta ttatgccatt ttcatggtcg atattgataa tttgtacagc agtcaatgct
     2101 attggattgg gtcttatagg tgaccttgtt gcaaatattc ctataacgtc tggtccactt
     2161 ttataaggtt ttggggtttc taaaatactt cttagttcag gatcatcaaa cccatcagcc
     2221 caccaaaata catttaaatg actgaaatcg tcgagttcat ttaatgcagg tacatacttt
     2281 ttgtctaatt taataaagac ctcttcgcct tgaatacata ttttacctat aggatttatt
     2341 aatatttctt tcataatatt acctccaact atttaattta tcatttgtaa ttttagggta
     2401 taacatgaca tcatgtgagg gtcaatataa aataataaat aaaaatatta atagttagaa
     2461 tgataataca ttttttacat ggagcatgac accagtaata aggcaatctt cgtcaatatc
     2521 aaaagtagag gtatgcaaag gggaagtaat gtttttttca cgatttgcac aaccaaggtg
     2581 gtaaaaagct ccttcacagt gtcttagaaa atacgaaaag tcttcagccc caagagtggg
     2641 cgagtcttta aggataatat tttcttcacc aaacaattct acagcatttt gtttgacgta
     2701 atctactaga tggtttgaat tgataagagc tggataacct tcctcaattt caacagaaat
     2761 acttcctcca aatgttttac aagtaaaatc gcaaatttct ctaattcgtt tttttgaaaa
     2821 ctctctagtt tcaggagtca aggttcttaa agtacccctt ataaccactt tatcacaaac
     2881 tatattttgc ttgattccac cttcaatttt tcctagagaa ataaccacag aatcagttgg
     2941 atttgtgttt cgactaacga ttgtctgtag agctgtaata atatgagcag atataacaat
     3001 agcatcaata ccttgatgtg gataagctcc atgacatttt gaaccatgta cagttaattg
     3061 aagtgtatcg gtggaagcat ttagagtgtt gtattttaat tcaattagat ttttgttgat
     3121 attgggattt acatgaagtc caaatatata ttttacattt gggttttcaa gacatccatc
     3181 ttctatcata agttgagccc caccaatagt ttcctcggca ggttgaaaaa agaattttac
     3241 atttacattt aagtaatcct ttaatttaaa tagtatatta caagtaccca gtaaaatagc
     3301 agtgtgtgca tcatgaccac atgcatgcat tttgccaata ttaatagatt tataagaata
     3361 attaagttct tctgttatag gtaaggcatc tatatcagct cttatagcaa ctgtttcaaa
     3421 gtttggactc acgttaatgt atgcagttat ccctgtatga ttcttatatt caatataatt
     3481 tatacctatt tcatttaagt atttaataat ttttttctta gtttgaaatt cttctaatcc
     3541 aagttctgga gtcttatgta aatctcttct tatatttata acccaatcat ttatctcatg
     3601 acaaagagtt tttatattaa gcataaaaca catcctaact atattaaaaa tttatttttc
     3661 ttcattaatt atattatttt atgtaaatca ttattatgta tcaagtacaa ataaaatatc
     3721 ttataattat attagagata tttagtatgg agaagaatat atcattttat aagaagaggt
     3781 gtttaaatgt taggaataat tgcgccatct gggccattaa gaaatacaag tttggaggaa
     3841 ataaagttta atttagaaag ttatggttac gaagttaagt tttctgaaag ttgtagttta
     3901 aattataaag gttatttagc tggtaatgat gatattagag caagggatat agaagatatg
     3961 tttttagata aagatgtaga tataattatg tgcttaagag gaggttatgg aacaacaaga
     4021 atattggata aaataaatta tgatataata aagcaaaatc caaaaccatt tataggtttt
     4081 tctgatataa caggtttaaa tttagctttc tataaaaatt gtggtctttt accatatcat
     4141 ggaataatgg cagcaaatgt aggtaaatgg gataaattta cctataaatc attggtaaat
     4201 gctttagaat ttaaagatga attatattta gaaaatccaa aagaagaaaa gatttatact
     4261 gtatgtgaag gtaaagcaga gggaataata atgggaggaa atttatcctt aataattgcc
     4321 acaatgggaa caaaatatga aatagatgca aaagataaaa ttttgtttat tgaggaaatt
     4381 ggagaacctc aatataaatt ggatagaatg ttaacacaac tatattcttc aggaaaactt
     4441 gaggaatgta atggtataat ttttggagat tttaaggatt gtattgaaga aaatgatttg
     4501 atggaattac taatagaatt tgcaaataag gtcaataaac cttctatata taatcttcag
     4561 tcaggacatt gtatcccaat gataactatt cctttgggca gaatgtgcga attagatgct
     4621 acagaaaaaa tcgttaaatt aaaaaaatag tgtgtatata aatataatag aaatatggta
     4681 taatcttata caagtaaaaa tttagctagg aggatgaaaa atgtctgatg atagaataat
     4741 agactttaac gaactaaaga acaaagttaa agattctgat gtagataaat ttgagcaata
     4801 catatataac ttatattttt ctgttatgga tggaaagatg tctatggctg agttttcaag
     4861 aaaaatattc gattatatga gagataacaa catatctcaa gaaaaattta tgaaaataca
     4921 aaagcaattt atggagagat atggtatgga cactgaagaa gtagaaaaac aacttagaaa
     4981 ctttggaatc gacccttcta cagcaggttt tatgagtaat aatacttcca gcaaagtatc
     5041 tacagaagat ttagagtcat ttaagaagag tgcaggattt tatgagaaat atggagaaaa
     5101 aatccaacca aagagttgta taacaacatt tataaaaaat gacttaaatg atattaatgt
     5161 aataatcgac caagaaaaga taatgctttg tagtgataga aaaataaatc ttatggattc
     5221 agaactaaat gagtttttat tagaatataa gaatatgttt aataaaaaaa taaaggtagt
     5281 aatgtgcgaa actacgaata agtatgatta ttaaaaaatg aatttaaata ctgaagtagt
     5341 atcaattaat tgtactactt aaaaataaaa atcgcaattt attattcctt ataaatttgt
     5401 ataaggaata tctaaactgc gattttttat attgtgaaga ttagtcataa tagatagtgt
     5461 tttaaattgt aatcttctca ctaaaactgt gtttttctat tagaaatttt attaaaaata
     5521 aatatctgat aattgtatta tatgggatgt aaagtattag aggcttaacg aatctctttt
     5581 aatacattaa ctccattttg aatcatactg ttgaaaaata ctaagtttaa aatctcagca
     5641 gggtgaacgt taggaatatc ataagtatct actaaattca taggtacaac tatatttttt
     5701 tcaatattat gttgattaaa atatgatttt agagttattg caaattgata tatacatata
     5761 tctgtgcaat cgccaactat aattatatta tctatattat caaaatccaa attttctaat
     5821 gcaaaaaatc cattagtaga atttttagga agaatttgta ggttttctat cgacttaagt
     5881 tcatcaacca attcactttc tacatcattt tccaaacagt gaacaggata actcaaaagt
     5941 tctattgatt taggagtatg agaatcagta aatgctatta ctttatttaa tttgtttgat
     6001 attttttttg taaacatttc aattggcttt attaaagact ctactctagg agagtataat
     6061 gcaccttgtc ttgcaaagcc attattaaca tcaattataa ataaagcagt tttactcaaa
     6121 tcataatttt ctattttttc tattggtaga ttatctaaat tactctttaa agcttcaagt
     6181 tcatttaata agttatccat agttatacct ccaagataaa tttaataaaa ttgtacatat
     6241 taattatata aaagtcaagg agtacaaact attgtataat tagctgtatt gttttgagtg
     6301 taaaagattt gaagcaatat ctggatagtt agtaaaaata ccatctacat tgagttttag
     6361 gcagtgtagt atatcatcct cttcatttac agtatataca ttgacaccaa gtagattttt
     6421 gtgacaaagt tcaattagag attcatttac taaaactaga ggtggatgaa ggtaactatt
     6481 acccagaaat ttagcaaaat tgactacatt gtttataggt aaataacaca ataatcctgt
     6541 ttttacacta gggtctaatt tatgaaagtt ttttaagcta ttgctgttga aactagatat
     6601 aagaactcta tttttcatat tatactttaa aataagctct aaaacgtctt tttctatatt
     6661 gggatagttt attttgtcag tttttagttc tatatttaaa ataaggtctg taggtgaaat
     6721 tagaattaat acttcttcta aagttggaat tttacattct ttattgcttt gatatccttc
     6781 aaaagatgag tttagagttt ttaattttct taaagtaaag tcttttacaa aaccatgtcc
     6841 attaaaagtt ctatcaacct tttcatcatg aataactaca atttttccat ccttagttct
     6901 gtggacatca agttctattc catatatatc catatccaaa cattttttaa aagctagaat
     6961 agtattttct ggatactttc cactaaaccc cctatgagca taaatattca tttatatggt
     7021 tccctcctat aagtataact tatcttataa aaatttaatt aata
//
LOCUS       DAEPXW010000151         6910 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.155, whole genome shotgun sequence.
ACCESSION   DAEPXW010000151 DAEPXW010000000
VERSION     DAEPXW010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6910
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.155"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            55..1311
                     /locus_tag="KRM55_003442"
     CDS             55..1311
                     /locus_tag="KRM55_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1595632.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            1334..3415
                     /locus_tag="KRM55_003443"
     CDS             1334..3415
                     /locus_tag="KRM55_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBH1595633.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKPKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            3452..4537
                     /locus_tag="KRM55_003444"
     CDS             3452..4537
                     /locus_tag="KRM55_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH1595634.1"
                     /translation="MRKYMNEFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            4591..5715
                     /gene="wecB"
                     /locus_tag="KRM55_003445"
     CDS             4591..5715
                     /gene="wecB"
                     /locus_tag="KRM55_003445"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBH1595635.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENINSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKHSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            5793..6767
                     /locus_tag="KRM55_003446"
     CDS             5793..6767
                     /locus_tag="KRM55_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH1595636.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQSLENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT         2879 a          647 c         1148 g         2236 t
ORIGIN      
        1 aaataaatga ttttatatta gaatcaatat tttaaaatat tttaggagaa atttatgaga
       61 gatttaaatg tatcagagta tttgttcgta tttagtctgt ttagtatatg gtctttattg
      121 cttataaata ttattttagc tatgggtgga tatatatttt attttaaaaa ctttgataaa
      181 gaaataaaag aaattgatga atatcctatg atatcaatac ttgttcctgc tcataatgaa
      241 gctaaagtga taggtagaac tgtggagtct ttgctattac tcaattatcc taagagtaag
      301 atggaactta ttgttataaa tgacaattct tctgataata gtaaagaaat tttagaaaat
      361 ataaaggata ggtacaacaa ttataatttc actataataa atacagatag tttaacaggt
      421 ggaaaaggaa agtctaatgc attaaatatt ggatatacga tttcaaaagg agattttata
      481 gctgtttatg atgcagataa cacaccagat aaaaatgcac ttagatatct agtacaaact
      541 atagtaatga atgatgaatt aggtgctgtt attgggaaat ttaggactcg aaataaaaat
      601 aaaaacctat taaccaaatt tataaatata gaaacattaa gctttcaatg gatgtcacaa
      661 gctggtagat ggcaactttt taatctatgt acaataccag gaactaactt tatattgagg
      721 agaagtatca tagaagaaat tggaggatgg gatagtaaag caattgcaga agatacagaa
      781 ataagtttta ggatatataa attgggatac aagataaagc ttgtaccaca atctataaca
      841 tgggaacaag agccagaaac tgttaaggtg tggataaagc aacgtactag atgggcaaaa
      901 gggaatatat atgtattaat gaaatatata aaaaatatat ttaaacaggg aagaaataag
      961 attgtgtttg atatagctta ctttttttct gtatattttc tatttttaac atctgtaatt
     1021 atatccgata ttttatttgt tttaagtata tctaaactag tagaaatttc tattccaatt
     1081 aacttttttc taatatggat actatcttat cttttattta ttatagaagt gagtataagc
     1141 cttactatag aaaaaggtga agcaacaatt gaaaatatat tcatagtggc aataatgtat
     1201 tttacatact ctcaactatg gctgtttgta gctataaaag gaatgataga gtatctaaaa
     1261 gatataattt ttaaaagaga ggttaaatgg tataaaacag aaagattttg attcatgtac
     1321 aggaggaatt aacatgaaaa aatttattat atcaattata tctttagtat tgtttttttc
     1381 aaatatatca cttatataca aagtaaatgc tgatgagact aaagttaaaa attataagtt
     1441 tgaaagagat ataactattg atggtgttat aggaagtaat agtacttttt ttgaagtaaa
     1501 taaaaattgg gatattgaag aagttttatt gcatcttaat tttagtaaga gccaaatatt
     1561 aaatggagat gtttcaagtt taactgtatt gataaataat gtaccaataa aatctattaa
     1621 attaaatgct aagacaaatt ataaaaatac attagaagta ttagttccaa aagattatat
     1681 aattcaagga tataatgaaa taaaaataaa aacatacaaa acaatatctg ataaaatttg
     1741 ccaagatgat tccaatactg ggaactggat ggttattcac aaagaatcat atatatcaat
     1801 tagatataag cagaaaaagg tggaaaactc aataaatgaa tatccgtatc catatgcaga
     1861 aattgaaaat aatcataaat tagatacaac tatagtagta ccagataata tgactagagg
     1921 agagactaca gcagtgttta atttggcatc agcatttgga aaaataacaa aaaatgatga
     1981 tttaaagtta gatgttaaat tatattcaga aatgaaaaat tggtcagatg ataatattat
     2041 atatattggt aaacctgaaa atacagcaga agaaattttg gatattttaa gtataaagga
     2101 acaaacccta ttatcttcaa actgtataat caagcaagta gattcaccat acaataagaa
     2161 taagaagatg atggtggtaa ttggtagtaa tgaagatgat ttaataaagg catcaaattt
     2221 attaatagaa aatagacttt ctaaccaagt tttatcatca tcagtacttg taaacaaaga
     2281 gactaatata aaaattaata gggaacaaaa attaaattta ggtcatttaa cattaaaaga
     2341 tttaggatat tctgactttt tgttggaagg agcatttaat caacaagctt tgtttgatgt
     2401 caaaatacca acgggtaagg tattagatga tggttcaaag attatcttaa atttaagata
     2461 ttctgacaat ttagattttg aaaaatcttt agttacagtg tctataaatg atgttattgt
     2521 gggaagtaaa aaattggata ggtcacattc taataatgat aagttagaat taaaaatacc
     2581 taaagatata gataataaaa actattatca agttaaattg acatttaatt tgagtataaa
     2641 aaattcgaat tgtgttacta gagagagtaa taatccttgg gcatatgtat caaataattc
     2701 ttatttggcg ttatctacga aagaaaatga aaccttatct tttgaaaatt atccgtatcc
     2761 atttgttaga gatgatgaat ttaatgattt aactgtgata atgccagatt attcagggtc
     2821 acaagctatg acctggatgt ttagattagg tgttacttta ggtgcgaata taaattcaca
     2881 taatggaaat ataaatgtaa ttagaggaaa agaatttagt gacaagtata aggatactaa
     2941 tattgtagtt tttggagtgc cacataataa ttctgttata aagatgttaa ataataattt
     3001 aaatataaag ttcgataaaa attactccaa ttttatatca aatgataaga taagctttat
     3061 tgatgattat ggaaaaaata tttctaccat tcaattaata aaatcaccat ataataatca
     3121 aaaaaatatc atggtaatta gttcaatgaa tgaaaaaaac ttatatttag gaatggatta
     3181 tttgttgaat aaaagtaaag ttaatgattt aaaaggagat acattgataa ttgatgaata
     3241 cggagaggta gaagatttag cttataattt aaaacctaag aaagaagtaa aagattcaag
     3301 ctggaatatg agtataaata agacaactaa agtattttta atgatttctt ttattactat
     3361 aattgtagtc atgatattat caatgctata tataaaaaaa tataaaagaa gataatatga
     3421 taaatttatt attttaaaag aggtatataa tttgaggaaa tatatgaatg aatttaaatt
     3481 aaaaagaagt attttaatct cattaataat cttaattttt atatttatag tttactttgt
     3541 aagtattgag ttaaaagata ggagtctagt aaataatcaa tataaaggta agattaaatc
     3601 agccaattta tctgtagatt atgaaataaa tcaagttatg aaggatatag ataaattggg
     3661 attgaataca gtaaatgtac ctataattat aaatgtagag tccattaatt ctgatattat
     3721 gtcaatagat aataatagta aagaaaaggc aattaagtta ataaaaaaat taaataaaaa
     3781 aggtatttca acaatattag aggcatatcc atggattgaa aatggaaaat tgtatgagac
     3841 tgactggaac cctataaata aaaaaagatt tttttatact tggcaaaatg ccatattaaa
     3901 tgaacttata attgatgtag caaatccact ggatgtaaat gttttaaata ttggttctaa
     3961 ttttgtacat ttggaagaat atcaacaaaa ttggggtgaa ataatagatt ttgtacaatc
     4021 caaatttgat ggtcttgtaa cgtacagaac taattggtgg tatacaaaaa aagatgattt
     4081 aagtagtaag ttgttttatg aacaaaagtt gaacaataat ttttttgata agttagattt
     4141 tatatctata gcagcatatt ttgagttaag taataaacct gttaatacag tggatgaatt
     4201 aatttctgcc ttacactcat ctactgtaaa caatagagga caaaatataa aacaagaaat
     4261 atataacctt tataaagctc atagaaaacc tatatttttt ggagaattag gtttttcaaa
     4321 tagagaaagt gcaagttctc agccgtggaa tcatactcct tcaaaagctg taaatggcga
     4381 agaacaagca aggtgttttg aggcatataa gaaagttttt gaaaatgaag actggataaa
     4441 tggtttttct gtgttttgtg taggtaaaat agatgacgaa aaaaattttt acccatcaaa
     4501 agagagtata aaagttatta agtcttggta tgaataattt tgaaagtgta gaatttatat
     4561 agattaaata gatgattagg agagatataa atgaatgaca tcaaggttat gactgtattt
     4621 ggaactagac ctgaagctat caaagtagca cctttaataa aggaacttga aaaaagagag
     4681 aatataaata gtattgtttg cgttacagct caacatagag aaatgcttga ccaagttata
     4741 gaaaccttta atataaatgt agactatgat ttggatataa tggaaaaagg acaaagcctg
     4801 aatgatataa catgtaagat tttaaataaa cttcccttga ttttaaacaa ggaaaatcca
     4861 aatataatat tggtacatgg agatacaacc acaactctag ctacaagttt gactgcattt
     4921 tataataaaa ctcttgttgg tcatatagaa gctgggctta gaacctatga taaacattct
     4981 ccttttccag aggagttaaa tagacaactt acaggtatta ttgctgatat gcactttgct
     5041 cctactaatt tggctagaaa aaacttgatt tctgaaggaa aacctaataa taatatattt
     5101 gtaactggta atactgctat tgatgcttta aagatgacaa taaaagaaaa ctataatcat
     5161 cctataattg atgagattgg taacgatagg atgattttgt taacctctca cagaagagaa
     5221 aatttgggta aacctatgaa aaatatattc agagctataa agcgaatagt agatgacttt
     5281 gaagatgtac agatagtata tcccatacat ttaaatccta aaatacgaac tatagctgat
     5341 gagatatttg gaaaatttcc tgaaaaaatt catattatag agcctttaga tgtagctgat
     5401 tttcataact ttttaaataa atcttatatg ataatgactg atagtggagg aatacaggaa
     5461 gaagctccat cattaggtaa gccagttctt gtgttgcgtg ataaaacaga aagaacagaa
     5521 ggaattgaag caaagacact taaattagta ggtactaatg aagatagaat atataattca
     5581 gtgagcgatt tattaataaa taaagataac tatgttcaga tgagtaaagc atctaatcca
     5641 tatggagatg gaaatgcaag caaatatata gtggatataa taattaaaaa atttaattgc
     5701 aaatatttaa attagataag gcctaaaaca ttaactaatt gatataagat ttatgataat
     5761 attaaggaat acaattttta agggggagta atatggctag aaaattaata aaaaatttgg
     5821 gtaaaagtaa aagtgtaaag agagtgaaac ttttatttaa gaagattttt attactgtat
     5881 tcatagtagc aagtatagtt gctattttta atataacgaa atattttgag gaattataca
     5941 aagtaaggga tttaaaaagt actaaaattg aatactatat ggatgtggct gatgaagcag
     6001 gagatggaaa ggtccaatta agttggaagg ccttacttgc tatagacatg gtaatacatg
     6061 atgaagattt aagtaatata aaaaagaaag acacattgga tataggggaa aagtttatag
     6121 tagaagataa aaatgataaa ggcgaaaagg tgtataaggt aaaaaagttt aataaggtat
     6181 taagcgaatt gaaatttgac tcttctcaaa aaagtagagc aagaaaatac atgaaagatt
     6241 tggaatacac ataccttgga aataaacaat tagatagtag tgatgaaaaa attaaattta
     6301 taaagaagtt agaagactca gctataagag aatatattga ttatggaata ttgccctcta
     6361 taacaattgg acaagctata ttagaatctg gttggggaaa ttctaaactt acaaaacaga
     6421 gtaataattt atttggtata aaagcagata aagcatggaa aggaaaaagt gtagaaattt
     6481 caacttcaga gcattataat gaaaaaattg tagctagttt taggtcgtat aattcattac
     6541 aagattctgt caaagaccac agtttatttt taattaataa taaaagatat agaaaacatg
     6601 gattgtttga ggcaaaagat tatattagtc aagctcaatc attagaaaat gcaggatata
     6661 gtacagcaga agataaaaaa ggaaatcgta tatatgcaga gctattaata gatgttatta
     6721 ggagttataa tttgcaattg atagataata aagttgagac aaaataattg ttaactttat
     6781 atgaggagat aacaagataa gattcttttc tacaaaaaga atagaaaaat tgtaaaaaaa
     6841 actaaaaaaa tgtattgact tgttatttaa aaggtgatat tattattact gtactcgaaa
     6901 gagaacaaaa
//
LOCUS       DAEPXW010000152         6883 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.156, whole genome shotgun sequence.
ACCESSION   DAEPXW010000152 DAEPXW010000000
VERSION     DAEPXW010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6883
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.156"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(<1..138)
                     /locus_tag="KRM55_003447"
     CDS             complement(<1..138)
                     /locus_tag="KRM55_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595637.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KN"
     gene            complement(786..1193)
                     /locus_tag="KRM55_003448"
     CDS             complement(786..1193)
                     /locus_tag="KRM55_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595638.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1667..2551)
                     /locus_tag="KRM55_003449"
     CDS             complement(1667..2551)
                     /locus_tag="KRM55_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1595639.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2842..3318)
                     /locus_tag="KRM55_003450"
     CDS             complement(2842..3318)
                     /locus_tag="KRM55_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBH1595640.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            3584..4759
                     /locus_tag="KRM55_003451"
     CDS             3584..4759
                     /locus_tag="KRM55_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBH1595641.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4840..5643)
                     /gene="proC"
                     /locus_tag="KRM55_003452"
     CDS             complement(4840..5643)
                     /gene="proC"
                     /locus_tag="KRM55_003452"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH1595642.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5683..6267)
                     /locus_tag="KRM55_003453"
     CDS             complement(5683..6267)
                     /locus_tag="KRM55_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595643.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2268 a         1155 c          760 g         2700 t
ORIGIN      
        1 gtttttataa acatctattc ttttagcaag atacttatta tatacaaatc tacaacatcc
       61 aaaagttttg ttaattaact cttgttgttt tttatttgga tacattctaa acttataagc
      121 ttttttcact gctatcacct cactttaatt gttttttgat acacttttta atgattttat
      181 cacattttat cacatttaat atattatata atgctgtggt aaacaattta ttaatcacct
      241 ataataatgt taacaaatgt aattatttaa aacaattatt tagaaggttt tatatttaat
      301 tttaaataac atatttaaga accgtaagtc ttaactttta tcattttgag gttgtcgttc
      361 acataagttc gctactacct atgcagttct cttatgaact tcttacattt tcatgtaagc
      421 acagactata tcttatcctt cagcattatc cgttaaggtc tacccacttc cactaccaat
      481 agcttgtagt gtacttccct caagaggaat agtcgttgaa gtttctcctg ttcggagttt
      541 acctgctgat tgcccatttt aaagtactta ggatttaacc ttataccatc taaccaattt
      601 tttctacttt cgtaactttc acacttaggt ttatttcatc cttatgtttt agtttgatta
      661 gctttagggg tttccagcaa ttcaagtagt attggatagg ttctatccta tctctacata
      721 taggtttccc tatatgctga ctattttagc tactaactca tgactaaagt cacgagtgtg
      781 tgtagctatt ttttaatcaa tattttagta aattttacgg taagtaaaaa cctctctcct
      841 tcaaatccta tagcaaatat acttacaagt tgctttgaga aaataactcc taatatagct
      901 acaactatgc atataccaac tattatattt aaaacattgt ttaaaaactt tagtgcttgc
      961 ttttcacctt gtttactact tatatcttga tacattggaa taaaagtagt aactatagca
     1021 gtacctattg ctgcaaatat aatatttggt atattcatag ctgttaaata actctctgta
     1081 tataagcctg taccataaat tgatgataat actaattctc tacccattcc aagaatctta
     1141 gagattatag taactatcat caaataaaaa gttgctttag ctaccttgct cattttatca
     1201 ctccacttct aacatacctc tttttaatca agtaaaattt agctcattag atataattct
     1261 atcaactaat ttgccttgct tagccctatc aaaatataat taacacctat ttcttaatat
     1321 atcacaaact acattattct tcatattttt ttatttctcc aataagtttt acatttttcc
     1381 tatataaatt gtatagcttc aattatattc aaagaaatgg agttgctacc cgataacttt
     1441 aaaagtaaaa aacagatttt attatctttt taaactatat tctaacatat tttgtccata
     1501 ttgagaaatt ttactaaact attatgtact ttattaaata aataaaataa cagcacacct
     1561 ataaaataca agtgtgctgt tcataaacag attttataaa aaaataattc ctaagtagag
     1621 attaacatgc tttctcatac tctcatatat aatgtgtcta aaaatattaa taaaaatgtt
     1681 ttaattgttt taacttactt ggatgtctta attttcttat tgctttagct tctatctgtc
     1741 ttattcgttc tctggtaact ccaaatacct ttccaatctg ttctagtgtt ttagggtcat
     1801 catcatcaat tccaaatctc attcttaaaa cttgctgttc ttgctctcca agacctgtaa
     1861 gtagttcttc tatcttttct tttaaattat gctgttcaac ttcgtgtatt acaacatctt
     1921 taaaatcagc atctgatggt ataaattcaa ctaaactact atcctcatct tcttttaatg
     1981 gagtatccaa agatacaaca tttttatctc ttcttaataa ttccaacact ttgtcaactt
     2041 ctaagccaca tgcatctgca atctcatcta tagttggctc tcttaataat acatttaaaa
     2101 gttcttgttt ctttttcttt acaaaattta ttctctgatg aagatgtata ggtatcctaa
     2161 tagtattttc gcaatcgtcg atatatcttg ttatactttg ttttatccac caagttgcat
     2221 aagtgctaaa tttgtatcct tttttataat cgtacttttc tacagctttt ataagtccta
     2281 tatttcctgc ttgaattaaa tccaacatat caatactatc tcttttatat ctctttgcta
     2341 tgctcactac caacctataa tttgaattta taaatttttc ttttgctact gaagatgagt
     2401 tgattatttc cttagccagc tctacctctt ctcctgctga caacattttg tattcctcta
     2461 tttcctttaa atacattttc atcgcattcg atacatttga tgaacccaca caaatataat
     2521 tttcataatt attttctttt ttagtatcca taatcaaacc ccttctattc atagaatttg
     2581 ctaaaacaaa aataaataat ttaaacctac ataatctaca attacataat atcccattct
     2641 ttaaatgaat tgttttgtat attatgtata caaatttata aaaactatac ctataatatt
     2701 attctacttc taacagcaat atcctcctta tatatataat ttattttatt atatgttgtt
     2761 atattcttag ttttttgaat gatatatgtc taaaaaaaga ctgtttacta aacagtcttt
     2821 ttttatatat atgctcaata tttaattttc atgatgatga ttacatccac atccacaatt
     2881 ttcatcatgg tgatgatgtt cttctaaatc ttttacctgt tgttccattt catgaaactc
     2941 ttttaccatt atatcataag ttggaagagc tgcctcagta tcgtattctt cccctctcca
     3001 atcagcgtac atcatagcat ctccattagt taaaaccaat ctacctgaca tagttatatt
     3061 atccacttct tctaaaaatt ctatttgttt ttgtaaaact tctccttcta actccacatc
     3121 ttcatctaaa cattgcacta tcattacagg tgcataataa tcttcttcat ctttaacatt
     3181 tacaacaata tctaaaattc cttctgcacc ttcttcaaat tctgccaact caacatttgt
     3241 atcaatcata tcttgaggta ctaataaatc ttctattaaa tattttatta ctctatcttt
     3301 tactaattct tttgacattt atttttctcc ttccgattct ataacattat cataatcatt
     3361 tctatattat agtatactac attaattgtt ttttcaatct cttacaaaaa ttatttttta
     3421 ttatcttcct tatattccct tttttattac aaagttgtaa tcgcattgat ttaaaaaata
     3481 gtttatattt agtataatag aaatgtagca catattttta ttcaatatat taataaaaaa
     3541 atatattgaa aatgtaatgt atgttaaatc taggaggaat attatgaagt ttaaaaaaca
     3601 aattagttct attgttgtgt ctactatgct tgtacttggg agtatgaacc tttcttatgc
     3661 agacggtaca aatgtagtta cacttggagc taacttatca gagtctcaaa agcagcaaat
     3721 gcttaattac tttggagtaa aaaaagacca agtcttagtt ttagatgtaa caaatgcaga
     3781 agaaagacag tatttacaag gtgttgcaac agagggtcaa cttggaaaag ttactatctc
     3841 ttgctcatac gttgaaccta ctaaaaaagg aaatggaatt aatgttaaaa cagcaaactt
     3901 aacttgggta actagttcaa tgattgcttc aacccttaca acagctggtc ttgaagatgc
     3961 aaatgttatt gctgctgctc catatcctgt aagtggtact ggagcattga caggaatcat
     4021 gaaagcattt gaggatgctt caggaaagaa acttgatgaa actaagaaag aaattgcttc
     4081 tgaagaattg gtagttacag gtgacttagg agatgatata gggcaagaaa aagcaacagg
     4141 tgtaatgaat gatataaaaa cagaaattgt aaaaaatggt acaaaagata ccaatcaaat
     4201 agcaaataca ataaataatg ttgtaaataa ttacaatatt actattacac cagaacaaaa
     4261 agaacaaatt aaaggtgtaa tgaaaaaaat agctgaccaa aattacgatt acaatagcat
     4321 gaaaaataca ctagataatg tatcagataa tgtaaatgaa caattaaaga aattaggtga
     4381 aagtgttaag ggttctggta tactagatac tattggtgga tggtttagtg gaataggaga
     4441 ctggttctct ggtttattct caggcggaga taaaaaagat ttgggaatct taaataatac
     4501 taatgatgag tctcttggct ctgatgctgt aataaattct acagaaggtg ttcaaataaa
     4561 tccacaaaat aatactaatt ctaacaatga tagtgataca aatagctcaa aaaatgatac
     4621 ttcaagtaat aatgaaaata acgatagttc tcaaacaaat gaaaacaaca caacaaataa
     4681 ttcagaaaat caatcaaata ataatgactc agttggtttc tttgaaaaaa taaaaaattg
     4741 gctttcaggc ttattttaga aattaaacaa ataaaaagaa ttgcctaaaa tggaaatttt
     4801 ctataaaagg caattctctt tatttacaat aaatttttat tactcactca tttttttaga
     4861 tttttctata catgcacata ttgcttttat cacagaagct ctaaaacctt cttcttcaag
     4921 tactttaact gcttctatag tagttccacc aggtgaacat accatatctt ttaattcacc
     4981 aggatgtttt cctgtctcaa gtaccatttt tgcagaaccc ataacagcct gtgatgcaaa
     5041 cttatatgct tgtggtcttg gcattcctgc aattactgct gcatctgcta tagcttctat
     5101 aaataaaaat acatatgctg gtgcagaacc acttgcacca attacagctt ctataagata
     5161 ctctggtact acctcagtat ttccaaaaga attaaatact tctgtaactg cttctaagtc
     5221 ttctttgttt atatttttat ttatagaaag agaagacatg gcttcattta caagagctgg
     5281 agtatttggc atagttctaa ctattttttt atcttctcct ataatagact ctatatcttt
     5341 tatagatttt cctgctgcta ttgtaactat aattttattg tcatctataa agtcttttat
     5401 ctcttccaaa atatcatcat atatatctgg tttaacagct acaattacta tatcagaggt
     5461 tctagttact tccttcgagt cttttgtagt atttattcca aaatttgcat ctattctatc
     5521 aagagttcct tgactatatg ctgatgctat aaccatatta ggttcaacta attttgaatt
     5581 tactattccc cctatcatag cgcttgccat atttcctgca cctatgaatc caattttttt
     5641 cactttagta cctccttatt gactaatagt aatcgttaaa atttaagctt ctttaactgc
     5701 atcagacttt tcaaatggat ttggtatact tactaccaaa attttcacta ccttattagt
     5761 atagttgacc caattatgat tgttcttttc actattatag tgtattgtgt ctcctggata
     5821 catttctatt tgttcatctc ccaaaaacac tgtaagagta ccctctaata catacacaaa
     5881 ttcctcacct tcatgtacgt aacaacaaat ttcctcacta ctcttacttg gaagaatttc
     5941 aattaatctt ggtagcattg ttttttcctt taaactagat gataaatgat aatgtataaa
     6001 tgttgagttt tctacatcaa atacttcttt ttcataactt cttaatacag ctcttttatg
     6061 ctcttttggc ttcataaaaa agtaagttaa ttctacatct agtacacttg ctatttttcc
     6121 taaggaatct gttgccacac ttgttaatcc tctttcaagt tgtgataaaa aaccaattga
     6181 caagtttgtt ttttcactca tatccttcag cgtcatttgc ttttgagttc tgagttgctt
     6241 tatttttgct cctatgtcct tattcaaaac catcacccct aaataatttt aattttttca
     6301 taatataaat acaaaaatat aaatataggt actgaaccta tctttatttc atttaaaaaa
     6361 atttttataa gtattactat aatttatcaa tctttttttg tctacatttt tacgattatt
     6421 tacgatttat ttttcacata tgtatattta atcttgccaa ctaaagatac attttttata
     6481 agcatttact ctttatataa taaaacttaa gttgttcatg agtcttcttc tggtttaatt
     6541 attaaaattt caaattatat tattatttct acacattatt acatccttta gtacaattat
     6601 aacataattt tacaatttaa tgatatctat tcaatgtctt tttttactct acaacatatt
     6661 ttattttaga gtttaatact atatatattt tttatataca gccttgtcat tttttagatt
     6721 gtcaagagtt attgaagtat tttatgtaga tttagatttt attttctaat ttctcattta
     6781 acaagaattg cttatgataa aaaataatat catctcaata agattcttgt aaatatatct
     6841 atattctaaa tataatttct ttttttgtca aaatttcttc att
//
LOCUS       DAEPXW010000153         6859 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.157, whole genome shotgun sequence.
ACCESSION   DAEPXW010000153 DAEPXW010000000
VERSION     DAEPXW010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6859
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.157"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     repeat_region   467..2011
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=467..495
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     gene            complement(2169..2453)
                     /locus_tag="KRM55_003454"
                     /pseudo
     CDS             complement(2169..2453)
                     /locus_tag="KRM55_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2661..3479
                     /locus_tag="KRM55_003455"
     CDS             2661..3479
                     /locus_tag="KRM55_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1595644.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            complement(3612..5732)
                     /gene="feoB"
                     /locus_tag="KRM55_003456"
     CDS             complement(3612..5732)
                     /gene="feoB"
                     /locus_tag="KRM55_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH1595645.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(5758..5985)
                     /locus_tag="KRM55_003457"
     CDS             complement(5758..5985)
                     /locus_tag="KRM55_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1595646.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            complement(6312..6752)
                     /locus_tag="KRM55_003458"
     CDS             complement(6312..6752)
                     /locus_tag="KRM55_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595647.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
BASE COUNT         2552 a          887 c          901 g         2519 t
ORIGIN      
        1 attaaaaata atatatcata aataaaataa taagaggtag atacagtttt aagggaatac
       61 aaaagttttt aattaaacta tgcttgttca gatagatatt tatttaagaa aaaagactat
      121 taaaagcaat atacaagaat gatatattag attgattaaa caagcataaa tattatgtaa
      181 aaaactttaa gttatagaat ttaaatctaa tgtagataga ttacgttttt ttgcttttat
      241 tatggtataa attggtatca atattcaaaa gtaatatatt tatgatataa taaaattata
      301 ggaattttgc agtgagcgat atttgtgaaa aaatttggcg taacagttga aatataaggc
      361 gttgagagtg catgataagc gttatcaatt gcactattgc tcgttcactg caaatttaag
      421 agagttgtat acgtgtaagt gttgaaaata ctaagtttat tttggggttt tatattaact
      481 atatggaatg taaatgataa tttggttcta aattattcat tttacattta agttttatat
      541 taactatatg gaatgtaaat tatccatttc gcctaatgcg tcttggtcgt cagcgtctgg
      601 ttttatatta actatatgga atgtaaattt ttcaaaagct attttcaaaa tttctcttgc
      661 tctcgtttta tattaactat atggaatgta aatcaataga attattatta tagaaagaaa
      721 tagtgttttg ttttatatta actatatgga atgtaaatgt aggaattgga gcattagcac
      781 ttgcgatagc aggtgtttta tattaactat atggaatgta aatcttcaat atctcctaca
      841 ttttcttttg cacgtttaat tgttttatat taactatatg gaatgtaaat agtaatagaa
      901 aaaagaggat ttactggttt agagatagtt ttatattaac tatatggaat gtaaatgtaa
      961 gtcactcttt gcacgagagt ggctttttgc ttttgtttta tattaactat atggaatgta
     1021 aatttagacg agattgtttt tatagataca ggactagaag ttttatatta actatatgga
     1081 atgtaaattt actaacagga acatcaaaag gaggtttaaa atccggtttt atattaacta
     1141 tatggaatgt aaattcccac acgtataaat caatttggtt ttctgctgtc gtgttttata
     1201 ttaactatat ggaatgtaaa ttgcaaaaaa atcggataac ctagttcctc tacaacttgt
     1261 tttatattaa ctatatggaa tgtaaatacg agtctaatat attttcgctt cttttattat
     1321 tctggtttta tattaactat atggaatgta aattgtggat ttaaagatgg aatagtaaca
     1381 aagtatatta gttttatatt aactatatgg aatgtaaatg caatatctcc tcttgtaatc
     1441 gctgaataaa gatttcgttt tatattaact atatggaatg taaatctata actttttcgc
     1501 caaaaacgtc ttttatatca ttgttttata ttaactatat ggaatgtaaa ttccaaaaga
     1561 acctcttttt ctgtttcatc aactgtgtgt tttatattaa ctatatggaa tgtaaatttc
     1621 tttgaaaagc atactttctt tattctatct ttagttttat attaactata tggaatgtaa
     1681 atatcgtaaa tttttgtata ggagtcatac ttataagagg ttttatatta actatatgga
     1741 atgtaaatca aaatgatttg aaaataacaa atatgtcttt attaagtttt atattaatta
     1801 tatggaatgt aaattataaa taaataaaca gaaacaaaaa tcaaatcttt gttttatatt
     1861 aactatatgg aatgtaaata tcataagaac cagggatata gggaaggtca taagcgtttt
     1921 atattaacta tatggaatgt aaatccatct tttgttgctt tacataaatt tatattactt
     1981 acgttttata ctaactatac agaatataat tttcttttaa tgtgttatct tatgattatc
     2041 tagttatatt agcatacaaa aatataataa aattacacta tattataaaa accaaaaggt
     2101 agtatagaaa tcctattacc tttttattat taattttatc agtgttttat tataaatagc
     2161 ttacataatt acacattttt tctgattaaa taatatgatg ctattgttat aatagatact
     2221 aatgctaatg atgttattgc agtatctaat cttcctatta ataaactcat ttctatatat
     2281 tcaagttcta ttaaatatta ataaaatatt tctagtttaa cagctttttc tctatctata
     2341 tttccatact ttaactctaa tttatctaaa gattttttat tacaataatt aactttatgt
     2401 ttaattaaat atcttattgt agcacctatt acaattttca ctctaacaag cataaatata
     2461 atattccatc caaaagttaa gagggtatat ctttttttat gatgggaatg ggtaaaatat
     2521 ttataactga catctaactg atatttaagc tttaaaatca aaaccatatt gattttctaa
     2581 aataataact acttgattta gtaaataata aagaatatag taactatata gacaacaaaa
     2641 agaaaaggag tgtataaccc ttggaaaaac agtattttac aacaggtgaa tttgctaaat
     2701 tgtgtggtat atctaagcag acattaattt tctatgacaa aataggtatt ttttctcctg
     2761 aatataaaga taaaaataat tatagatatt actcagttta tcaatatgat acacttgata
     2821 tattacaatc attaagagaa ataggaatga gtttagagga aataaaagag tatatacaaa
     2881 atagaactcc ccagctttgt gtgaaaatgc ttaaagaaga agaaaaaaag ataagagaaa
     2941 aaataaaaaa actaagaaag ataagttcta agatgcaaaa tagaataaat ataacagttg
     3001 aaggaatttc taaaatgaat agtgaagaaa tttatatatc caaaaagttt gaagaatatt
     3061 tagttctatc aagcgatttg agtaatatga gtaatagtga ttttatgatg gaattaatag
     3121 atttcaccaa ttattgtaaa tctaaaaatt tgtatcaagg atatgagttg ggagtaatag
     3181 taagtaatga aaatataaaa aatggggact atttaagtat atcaagtttt tatttgaaga
     3241 tagataaaaa aataaaggat aaaaagctat atgtaaagcc agaaggaatg tatgcttgca
     3301 taaaacatat tggaaaatat gaggattcat ataaatctta cgaaaaattg aaaaaatata
     3361 tatatgaaaa tgaatataaa attattggaa attcgtatga ggagagtata cttgactttt
     3421 tttgtgaaag taatgaagat aattatatga ctgaaatttc aatccaagta tccagataag
     3481 aattaaaata gagatatatt caaatgttaa gtaattttac ttatcattga atatatctct
     3541 atgctttata ataaagtata taaattttta aatagtttct ctaatatatg tctaatgtca
     3601 gttaatacta attatataaa taaattgtaa actgtagttg ttaaaaaaca aacaacaaaa
     3661 gcaagtatag taggcattaa gaatcctaag gcagtccatt ttaaactacc agtttctttt
     3721 tttattgtta aaagtgttgt tgcacaaggc caatgcagta aactgaacag cataacattt
     3781 aaagctgtca aataagtcca tccatgttct ctaagaactt gacctaaagc actaaagcta
     3841 tctaattcta tcatagagcc agttgctagg taagccatta aaagtatagg tacaactatc
     3901 tcatttgctg ggaatccaag aataaaagca agtaatataa aaccatcaag accaattaat
     3961 ttagctaaag ggtctaaaaa gtttgcaaca tgtgataata tacttaaatc tcctatatat
     4021 atatttgcaa atatccaagt tatgacacca gcaggtatgg ctaccattac agcccttcct
     4081 aaaacaaata ttgttctatc tattatagag gtatataaag ttcttcctat ttgaggaact
     4141 ctataaggag gaagttctaa tgtaaatgta gacggaactc cttttaatag cgtcttagaa
     4201 agagtgtaag aaaccaacaa tgttattata acacctagaa ttatcagtaa agttatgcaa
     4261 agtgcagttg ctacgcttga tacgaaagag ttggttataa ctgagctaaa aaatattgta
     4321 gatatagcta tcaaagtagg aaaacgacca ttacaaggaa caaagttgtt tgtaagtata
     4381 gctataagtc tttcccttgg agagtcaatt atcctacaac caataactcc agctgcatta
     4441 catccaaatc ccatacacat agtcaaacac tgttttccat gtgcacaagc ttttttaaat
     4501 aggtggtcta agttaaatgc aactcttggc aaatatccaa aatcctcaag tagggtaaat
     4561 aatggaaaaa atattgccat aggaggtagc attacagaga ttacccatgc taatgttctg
     4621 tataatccta aaaccaacat atcatttaac catgatggac aattaatact atttaatata
     4681 cccgaaatac ttggctcaaa tccgagtaat aaattagata ataaagtgga tggatagtta
     4741 gctccttcta tagtaatcca caatatagta cctaataata agagcattat tggaagccca
     4801 aatattttag atgttaatat tttatctact ttttcttctc tatcagttga ttttttagca
     4861 acattagaac aacactcatc actcagtttt ttagcataat catagttgat tttagtaaac
     4921 tcatctctta ttttctgttt atttatattg tctggaatct ttttctttac ttcattaata
     4981 gcatctatag aatctttgtc tatataatta ctcatagatt caaatatact ttcatcgcca
     5041 tcaataagtc taagtcccaa ccacctagaa tttatacctg gtataatatt atccaattct
     5101 ggttgaattg attttaccac attctctata ttttcattgt atctaacagg tttattattt
     5161 aatttatatt tgtcaaaaga tacatcattt aaagtatcca atagttcatc cataccagag
     5221 ccatttcttg cagcagttaa aataactgga ataccaagag aatcctctaa aagtttttta
     5281 tcaatagtaa tgcctttttt tctagcttca tctattaaat taatacacaa aataacttta
     5341 tctgtaagtt ccatcacttg aaatactaaa tttaaatttc tttcaagaca tgtagcatca
     5401 catactacta ttactgcatc tggattacca aaacatataa aatcacgagc tacaatttct
     5461 tcttgtgata aggcaaataa agaatatgtt cctggtaaat ctattaatgc atattcggta
     5521 tttttatatt taaaattacc acgagctgta gctacagttt ttcctggcca atttccagta
     5581 tgctgtctaa gccctgtaag atgattaaat acagtacttt tacctgtatt tggattgcca
     5641 gccaatgcaa ttacaaactg gtcttcctta ttgtctatat caaacatgtc ttttaaagaa
     5701 ctcattttag ttgagttatg tgtcaacccc atattaatat cctcctgcta gaaattttta
     5761 aatgtcagaa actaatatta agctactttc ttcttgtcgt agagctatct tgctacctct
     5821 gattttatag acagttaaat tattttttgg accttttcta actacatcta taacagctcc
     5881 tctagtaaga ccaagcgcta acattctttc tcttaaatta ccactagata atatatcttc
     5941 aactttgaca gtttttttca cttgaatatc gttaaggttt ttcataatag cacctccatg
     6001 cttgaaattt agcctgggct aatcttctta ttttaaacta tgcattatat tattaccttg
     6061 ttacttttac aaaaaaaaga taggcaagat gcctatcata caaagttggg tataattctt
     6121 acttttgggg aaagtagaat atagaataaa aattaacact ttgaatccat ataattattg
     6181 aattttgata ataaaaaagt cagaaagcaa aagccttctg actctatgta aggtattttc
     6241 aaatacctaa atatcaattc aatatttaat ttatacttaa attatatatt aacaatatta
     6301 gcttgtcaac actataatct cattttaata tgttcaatac ctgcttcgtc gtatacttct
     6361 gagatttctt taaaaccaca agataagtaa aggttcttta tataagtttg tgctgatagg
     6421 gttatattat tttcgtgtaa gttaactttt ataaaatcta tagcacaatc catcatttgt
     6481 tttgctaatc cttttcttct atgactagaa agaactaaaa ctctaccaat ggaaacatca
     6541 ttataagagc tgtattcttt aggaattatt ctagcgtaag cacaaatcaa tccattttct
     6601 tttaaaaata tgtgataaga gcttttatct atatcatcat aatcgtttaa tgaaaatatc
     6661 ttctgttcac aagcaaatac ctcatatctt gattttgcta tttcataaaa ttcatctaaa
     6721 ctcaaatcat taaagtgttt aattttaaac atagtaatta cctcctagca tcttaaaaaa
     6781 ctgaatatta agatacatta taccattttt aacataaata cctttattaa aatttatatt
     6841 tattaaaaat atttttaaa
//
LOCUS       DAEPXW010000154         6686 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.158, whole genome shotgun sequence.
ACCESSION   DAEPXW010000154 DAEPXW010000000
VERSION     DAEPXW010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.158"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            71..1195
                     /locus_tag="KRM55_003459"
     CDS             71..1195
                     /locus_tag="KRM55_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HBH1595648.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(1669..2493)
                     /locus_tag="KRM55_003460"
     CDS             complement(1669..2493)
                     /locus_tag="KRM55_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595649.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(2841..3896)
                     /gene="ispG"
                     /locus_tag="KRM55_003461"
                     /gene_synonym="gcpE"
     CDS             complement(2841..3896)
                     /gene="ispG"
                     /locus_tag="KRM55_003461"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBH1595650.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIKQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKRVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(4079..5083)
                     /gene="rseP"
                     /locus_tag="KRM55_003462"
     CDS             complement(4079..5083)
                     /gene="rseP"
                     /locus_tag="KRM55_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBH1595651.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(5096..6250)
                     /locus_tag="KRM55_003463"
     CDS             complement(5096..6250)
                     /locus_tag="KRM55_003463"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBH1595652.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(6414..6617)
                     /locus_tag="KRM55_003464"
     CDS             complement(6414..6617)
                     /locus_tag="KRM55_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595653.1"
                     /translation="MISYAPLWKLLIDKKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
BASE COUNT         2216 a         1187 c          692 g         2591 t
ORIGIN      
        1 acttatttta caatctttct tcaattgata tataatatgt ttatataaac taatgtatgt
       61 gaggtgaaat atgagcaaaa aaacaaaata tttttcttta attctctttc ctattgcttt
      121 gcttttaaat tttatagcca gtaaagttcc aaatattgtt gaaaaatatt actcccaatt
      181 catagataaa ataattgtac aaatattgag taaagtttct ggaattttcc cattttctct
      241 ctatgagatt acaatgtaca taatagttat atctatcttc ttatttttat gttgtacttt
      301 atctacaatt tttaataaga aaaaaaaatt aaacatatat ttaaaaaatt ccattttaaa
      361 tatattatcc attgtatcaa tagtctactt tctttttgta gtgctttggg gaataaacta
      421 taataggatt ccactagaaa ccacacttat aaataactat aatttaaaaa acaatacctc
      481 tatccaatca aaacaatata gtgttaaaga gcttactaaa ttatataaat tccttgtaat
      541 taaagcaaat gaaactagaa aactcacatt acaagataaa aatggtattg taaaatctaa
      601 tacagattat aatggtgtca taaatagagc tcaactagga tacgataata tcttggatat
      661 attacctggt gttagtggta gttattctaa gcctaagtat attatttcat caaatctaat
      721 gtgctataca ggaataactg gtatatactt tccttttaca ggtgaggcaa atgtaaatat
      781 agcaatacct gacttatata ttccttgtac agttgaacat gaaatggcac atcaaagggg
      841 atttgctagt gaagatgagg ctaattttat agcgtatctt acttctataa aacaccccaa
      901 tattgatttt aactattctg gatatatttt agctttaaat tatactgctt ctgctttaag
      961 taaggttgat tataatgcat atgttgatat ttctgctggc atttcagatt ctgtccgtag
     1021 agatttaaaa aatgaaagtg aattttggca aaaatatgaa ggtaaaatta atgaaatttc
     1081 taatgagttt aacaattctt acttaaaagc taatggcgtt actgaaggta ctcagagtta
     1141 tggtaaaatg gttgatttat tgctaactta ttatgaatta tatccatata actaaacact
     1201 acaattcaaa attttattca tatacagctg atattaaatc agctgttttc tatttaaata
     1261 aattatttaa cttcaagcaa tcttatataa tttgatagta cttatactat ctgtataaca
     1321 tttcaattct aactatttta gttaaaacat ttctattatc ttttttaata aatgttttaa
     1381 ctaaaatttt taaaacataa aacttccaca ttatttcact atctatataa aaatctaaaa
     1441 attcacatat aaaattacat aactaaaaaa tcataaattt atagaaaaca tatattcaaa
     1501 ataaaaaagc atgtatcaaa acttgacaca tgcttataat cttatgtata tatatcattt
     1561 tgtcacaata aaaatttact tgtaacactg atatttttaa acaaaatagt ccttatttaa
     1621 ttaaattaac attaattaaa ttcgtactca ttttgctatc attaaacatt acttatagta
     1681 attttctaat acactatttg aaacttcctt cccttgaaaa cttttcaacc aattctcata
     1741 tgctgagttt ttccatacac taccatcatt aaatgttact tgttttacac aagatataat
     1801 gtactttaca ccatgctctc cagttgattg tttccattta tcaaacaata gaaaggcatc
     1861 attttgattc ttacctggtg ctattgcatt ttgctttgca tattctttct ccatttgttt
     1921 ccattctttc aaccaatttt ctacccatgc cttgccttgt tgtttttcaa acatacttat
     1981 tatatcctgt ggtggtgatt gttgcatttt tctataagta tgtgaatatg attttggaga
     2041 cacaggagat atgcctgtaa caataccata gtctacacca gctgggctaa atccaacact
     2101 tcctacttcg ccatctgctg ccacattttg agcatcccaa tatagctcaa gtggttttcc
     2161 atttttatca tatgctaagc atgtaatttc ataatccata attgcctttt cactgctatt
     2221 tgttaagctt ataacattac taggccaatg atatggagta tcatcatact gtattttgct
     2281 attatttata aataatggaa tattctcatt ataaacaaga cctttactac tttgaatatc
     2341 tgataccttc tttgtgacag tacttaccgt atttgctaag tatacatttg ttttttctga
     2401 attagtcgta ctaagagaaa atgttgttgt cgttccagta atcagcaaag caacaactaa
     2461 aataggtaag ctagatattt ttttatatct cacagttctt cacctctttt tctattaact
     2521 tataataaaa caatttacca aaacattaaa atctatgtta acataattta ccaactgttc
     2581 tagtaactat atcctatcat agttactatc aagtttcaat actattgatg gaaattttca
     2641 ctatattaaa tcttttttta attttataaa tttacaatat gatttaactc atacatatat
     2701 agtcaaatta gaatataagt ttcttacatt taatgaagtt tataaaataa aaaatgacta
     2761 gataattaaa tactgtaaat aaaaacttat tacaaaagta tttaaaaatc tagtcattta
     2821 atatatatat gaattgtata ctataatttt tcaatctctt ctagcaactc atcaactaat
     2881 ttgttaccat caatcattct aactatttca ccctttttaa ataaaagacc ttcaccttta
     2941 cccccagcaa tacctatatc tgcttctctg gcttcaccag gtccatttac agcacagccc
     3001 ataattgcaa cagtgatatt tttttccata ctaccaatct tttcttcaac ctcatttaca
     3061 acactaatta agtctatatt acatctacca catgtagggc atgatataac tttaatctta
     3121 tcatttaaaa gtcccaaact tcttaaaatc tgtttaccaa caataacctc ttcaacaggg
     3181 tcgcctgtta aagatattct aacagtatct ccaattcctt taagaagaag tgctcctacc
     3241 cctatagaag actttattgt tcctttgtga acacttccag attctgtaat tccaatatga
     3301 agaggataat caactctttt tgatattaat tcatatgcat caacagtttt ataaatatcg
     3361 gatgatttta gagatataac tatattatga aaatctaagt cttcaagaat cttaatatgt
     3421 cccattgcac tttcaactaa tgcttcagca gttgcagagc catacttttt taaaagttct
     3481 ttctctaaag aacctccatt aactccaatt ctaattttta aatttctttc cttgcatttc
     3541 tcaactacca tcttaactct ctctatactt ccaatattac caggatttat tcttattcca
     3601 tccacacctt gttttatagc ttcaagggct agcttataat caaaatgtat atctgcaata
     3661 attggtatat ttacactaga ctttatcttt gctatatttt tagcagcttt aatatcagga
     3721 acagcaactc taactatatc acaaccagct tcctctaatc tctttatttg agctattgta
     3781 gcatctgcat ctcttgtatc agtatttgtc atagattgta tacttatagg attttctcct
     3841 cctattttta cagttcctac acttacttct ctcgtctttc ttctctcgta actcatattc
     3901 cacctctata tattatttta tattgaatct ctttaaatat taaaatatta taacctacat
     3961 gtatattata aattaaaaag ctatctagtt aaataagaat aaatttcata cataaaaatt
     4021 aatttattct tatttaaaac tacatagcct atattcttaa aatctctaaa aaactaaatc
     4081 attgaaataa tcttagtata tctttatatg tgataaaaag cataaataac attaaagctc
     4141 caaaaccaac aacatttatc atgccttctt tatttgggtc gagtttttta ccacctctaa
     4201 cagcttctag taacaacata agtattctcc atccatcaag tgctggtatt ggtaatagat
     4261 ttactatacc taaatttaag cttatgacag ctgctaaata cactacattt atgatgcctg
     4321 tacgagcagc atctgatacc ataccaataa cacctactgg tcctgctaca gcattgccaa
     4381 tccctcctgg tacacgtcct gtaatcattt gacctagaaa tgttagcatc tgttttgtca
     4441 tatctacagt agttttacat gcatttacta ttgaccccaa aaagtctttt tctctttgtg
     4501 gttgaatccc tatttcatac tttccattgt tatttttagg tgttacattt acaactttat
     4561 cacttccatc tctagttata ctaagtttta attctccacc agaagaagtg tttattatat
     4621 ttgcaacttc atcccaagtc ttaacagaat taccattaat tttatttatc ttatctccta
     4681 cttgaagccc tacagcctgt gcaggagtat ctggcattat ctttcctaat ttagtcgttg
     4741 gagaacctat atacaaaaat actgggacta aaagtattgc tgctaatatt atattgaata
     4801 ttggtcctgc tacaatagta ctaaatcttt gtaatataga cttgtttcca aaagaatttg
     4861 gacttatttg ttcttcatct tcaccttcca tgctgacata tccaccaatt ggaagtgctc
     4921 ttatagaata ctctgtatct ttttttacac tatatatctt aggccccata cctatagaaa
     4981 actcatttac tttgatacca cttctttttg caaatataaa atgtcctaac tcatgtatta
     5041 atacaattat actaaatagt attaatgcgg ctattatagt cataaattca ccttcctatt
     5101 tttttatcag atttgcaaca taagctctac tccatctatc tgtttctaag atttcttcta
     5161 atgttggttc acttatgcta ctatgaactt ctaaagtctt ctctatgtaa tatggtatgt
     5221 catagaaacc aattttatcc tctaaaaatt cacttactaa aacttcattt gctgaattta
     5281 aaacagaaga ataagttcct cccattttta aacactcata tgccaatttt aaacatggaa
     5341 aagtttctaa atctggttct tcaaaagtta aagtactaaa ttttgaaaaa ttcattcttt
     5401 caaagctact ttccattcta tctggatatg taagagcata ctgtattggt agtctcatat
     5461 ctggacatcc taattgagca attattgagc tatctgtata ctgcaccatt gaatgaatta
     5521 tgctttgtgg gtgaactact acatctatat tttcttgttc tactccaaat aaccatctag
     5581 cttctatcac ttcaagtcct ttattcataa gcgttgaaga atcaatactt atttttcttc
     5641 ccatactcca atttggatgt ttcaaagctt cgtttttagt tatatttgca agttctccct
     5701 ttttctttcc tctaaatgga ccaccagatg ctgtaagtat tatcttttct atattttttt
     5761 tattttctcc atttagacat tgaaatatag cactatgttc actatcaaca ggaagaatat
     5821 ttacattgta tttttctgct tctttcatta caagttcacc agcagttacc aacgtttctt
     5881 tattcgctaa tgctatgtct attcccttct ttatagcaca aagagttggg actaatccta
     5941 tcatacctac tacagcagtt aaaaggacat ccacttcatc aagtgatgat attattttta
     6001 atccttccat tcctgctaaa acttctattt ctatattttt aggcaacatt tcttttaatt
     6061 tcaatgcttt attttcctca aaaactgtta catatttagg tttaaactct actatctgtt
     6121 ctagcaataa ttcaatatta ctgttagctg atattgcaac tatctcaaac ttatctctat
     6181 tatctctaac tacatccaaa gtttgtttac ctatagagcc tgtagaacct aaaattgata
     6241 tctttttcat ataataatcc tttctaataa taaatatacc ctgtcaaaac attataacac
     6301 tactaaaaca attattttta ctattcatag aaatttcata tattattcca cagattaaaa
     6361 ttaatctatt attttttgta ttttgtggaa tattataaaa tattctagta ttattaaatg
     6421 ccctttttta tttccacaac atcttctatt ttacagtcta gtgctaaaca tatcttctcc
     6481 attgtatcca tagaaacaga tttatcattt cctagtctgc ctaaaacaga aatacttata
     6541 cctgatatat ttacaaattc cattttcttt atttttttgt caattaacaa tttccataat
     6601 ggagcgtatg aaatcatgtt atcacctcgc aaaatatatt ctatcacatt ttatctattt
     6661 tggaaaattt tcatctattt agataa
//
LOCUS       DAEPXW010000155         6686 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.159, whole genome shotgun sequence.
ACCESSION   DAEPXW010000155 DAEPXW010000000
VERSION     DAEPXW010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.159"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            143..283
                     /locus_tag="KRM55_003465"
     CDS             143..283
                     /locus_tag="KRM55_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595654.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(953..1273)
                     /gene="rhaM"
                     /locus_tag="KRM55_003466"
     CDS             complement(953..1273)
                     /gene="rhaM"
                     /locus_tag="KRM55_003466"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBH1595655.1"
                     /translation="MNTVRKCFKMKLFKGFENEYKKRHDELWSEMIDMIHEYGGSNYS
                     IFLDEETNYLYGYIELKDAKLWDKSSETAICKKWWNYMSDIMETNEDNSPVSIELKSM
                     FYLK"
     gene            1459..1740
                     /locus_tag="KRM55_003467"
     CDS             1459..1740
                     /locus_tag="KRM55_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595656.1"
                     /translation="MKDETLEDILKQKTQAERYILECIVTKNVKKLDNKKIVSILHTI
                     LCWEEINGTIVLTDKNILSLDEDIMISKHRRFIDIPKHKHNFIEFHLMS"
     gene            1864..2835
                     /locus_tag="KRM55_003468"
     CDS             1864..2835
                     /locus_tag="KRM55_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1595657.1"
                     /translation="MRQYIHDKLREITEEEKNILEGNYIIDKSIYTDNSQFIIDSNKL
                     LNIDELIHIRKHTRFAQFPKHKHNYIEFNYVYRGKLVQTIDEYKINLKQGELIFLNQH
                     VIHEIEASDEEDIIINFIIKPEFFDYIISLLENDNKIMNFLMTTLYTNYNLGEYIYFK
                     VSEKEEIQDIIEKIIIELYEPSVVNKVKIKLLVGLLLVELVKNSEDVENHAVDNYEKM
                     MIIEILKYIDKDYKKGSLSEIASNLNQGDYKISKLVKKHLGYTFKDLVQEKRLSKACE
                     LLVSTNLSIAEIIENVGYENLTYFYKIFKNKYGITPKEYKKNIKNGQ"
     gene            3042..4436
                     /gene="rhaB"
                     /locus_tag="KRM55_003469"
     CDS             3042..4436
                     /gene="rhaB"
                     /locus_tag="KRM55_003469"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBH1595658.1"
                     /translation="MRYYLAIDIGASSGRHIISYINNGKLEIEEVYRFKNNLIKKDGH
                     FCWDISKLFSEIKNGIKKCIKINKIPVSVAIDTWAVDFVLLDEKDNILGNCVSYRDNR
                     TDGIMEEAFKIIDKKELYLKTGIQFQKFNTIYQLLSIKNQQPDLLEKAKSFLMIPDYF
                     NFLLTGKKVTEYTNATTTQLVNTTTNNWDEEIINKLGFDKMLFAKIKTPKTILGSLKK
                     ELVEELGCDLEVILPVTHDTGSAFMSTPVKNRSILLSSGTWSLLGVELERPKCKLEAL
                     DYNFTNEGGYEYRYRFLKNIMGLWMIQEARKCYDSKHSFTELVEHARLSEGFKSIVDV
                     NDDRFLNPENMVQEIIKYCIETNQTEPQTVGEVAYCIFNSLAKSYSKSINEIEEIIGE
                     KLETISVFGGGCQNELLNELIAKESGKKVLAGPVEATALGNIVCQLIAKNELNDLEQA
                     RDIIRNSFDIIQYN"
     gene            4457..5713
                     /gene="rhaA"
                     /locus_tag="KRM55_003470"
     CDS             4457..5713
                     /gene="rhaA"
                     /locus_tag="KRM55_003470"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBH1595659.1"
                     /translation="MELKQRYEVAKKEYEKWGINVEEVLRVLSKVKISIHCWQGDDVT
                     GFEGNQQRLSGGIASTGNYPGKARNPQELRRDLDKALSLIPGKHKVNLHAIYAETGGS
                     FVDRDELKPEYFENWVKWAKERGLGLDFNPTIFSHPKSSDGLTLSHPDKKIRDFWIKH
                     CIASRKIGEYFGKELGQTCLTNIWIPDGYKDIPSDRLGPRRRLKESLEEILKVEINRE
                     YNLDCVESKVFGLGVESYTVGSNEFYLNFASKNNIISLLDTGHYHPTELVSDKLSSML
                     LFSDKVALHVSRPVRWDSDHVVILDDELKEIAKEIVRNDALDKVIIGLDFFDASINRI
                     AAWIIGTRNMIKALLSAMLMPHEELRKLQDEGDFTKRLAIMEEFKTYPMGDIWNYYCK
                     INNVAVKEDWIEVVKEYELTELLNRK"
     gene            5724..6539
                     /gene="rhaD"
                     /locus_tag="KRM55_003471"
     CDS             5724..6539
                     /gene="rhaD"
                     /locus_tag="KRM55_003471"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBH1595660.1"
                     /translation="MSIMEMNFIKDFMKITYDAWLKGWHERNGGNITYRLTPEEISGI
                     KEFITEEIEYIPIGVTVENLANEYFLVTGSGKFMRNISINTVQNVGIVKIDEKGENYA
                     IVWGLDKAKPTSEFPSHLMSHSIKKDKTNGLHRVIMHSHTTNLIALTFILPLEGKVFT
                     RELWEMATECPVVFPEGIGIVPWMVPGGIEIAKATQNLMEKHNIVIWAHHGTFCSGET
                     LDLTFGLMDTVEKSAEILVKVISMGGKKQTITGDNFRDLSKNFKVSISEDYLY"
BASE COUNT         2813 a          674 c         1093 g         2106 t
ORIGIN      
        1 taataaagac gataagtatt aaaattttat gtttccaata tttatgatat aattaatatg
       61 gcaaggaata aatatttgaa aaagctatga gtggtgtttc catggaagtt tcttcacttt
      121 cttatgagag gaggtgaaaa ctatggaaaa tctaatgatg agtattataa ctggtgttat
      181 agccagttac atttacgata aattaaagag ccactctgag cgaccaacta agagtggctg
      241 ggaacttaat ataaagttcc agaaaagtaa atcttcaaaa taatttgttg aaggaaacat
      301 cactcaaagt taagtaaaat atgtttcctt gcttttatta tatcacaaat taaaaatatt
      361 aacacaaaat tttgtgaata tatacttatt attgttctaa aaaaatatgt aaataattga
      421 tttgatttca tagaattatt gttgtaatgt ttagttaaat atacacaatc tcaattaaag
      481 aagataagta ctataaattc atatcaaaaa aatacataaa cttttaagtt ataaatttat
      541 aaaaagtctt ttagtatcat tatttcaaga ggaattaaca tatgaaaaaa taacttcatt
      601 agaaaagtgg ataaaaaaac tggtaagaag atgactaaag attacatata ctattactta
      661 aattaaaaat ttaatataaa caacacaaga tatatcaatt attctaaagt taagttaagt
      721 agtcttactg aatcatcttt gggaataatt gtttcaatgt ctaatagaaa taccacttgt
      781 ttataacatc tttagctact ataatcgaaa tatgttttta gtttttcaca gaacaattat
      841 cacatagact agaggttttt aggaatcact tatctttttt atacaaaaag gagataattc
      901 aaatttttat tttgatatat ccccattttg tgatttataa taatttttgt ccttatttta
      961 aataaaacat agatttaagt tctatagata cagggctatt atcctcatta gtttccatta
     1021 tatcagacat ataattccac cattttttgc agattgctgt ctctgaactt ttatcccata
     1081 gtttggcatc tttaagttct atatatccat ataaataatt agtttcttca tctagaaaaa
     1141 tagaatagtt actaccacca tattcatgaa tcatatctat catctcagac cataattcat
     1201 catgacgttt cttgtattca ttttcaaatc ctttaaaaag cttcatcttg aaacatttgc
     1261 gtactgtatt cataaaaaaa tacctcctaa attttaagta tttacctata aatgtatttt
     1321 aaaacaaaaa aaggtatttt taaatgtcat aatttaacat tattactgtc aaaaactaat
     1381 atgatacaat tagataaaga atatttgtaa tataatttaa aactgtaata aagtatagct
     1441 aaatctgggg ggatataaat gaaagatgaa acgctagagg atatacttaa acaaaaaaca
     1501 caagcagaaa ggtacatctt agaatgcata gttactaaga atgtaaaaaa actagataat
     1561 aaaaaaatag tgtctatatt gcatactatt ttatgttggg aagaaataaa tggaactata
     1621 gtactaacag ataaaaatat actttcttta gatgaagaca ttatgatatc taaacaccgt
     1681 agatttatag atatacccaa acataaacat aactttatag agtttcatct aatgagttaa
     1741 tatataattt tttattagga actatacaca aaggaaaaag atgtgataat tattatatat
     1801 ttaatgctaa aaataatttt aaattgaaac aactagtagt tgaactaact aaggaggtag
     1861 ctcatgagac aatatattca tgataagttg agggaaataa cagaagaaga aaaaaatata
     1921 ttagaaggaa attatataat agataaaagt atttatactg ataattctca atttataata
     1981 gatagcaaca aattattgaa tatagatgag ttgatacata taagaaaaca tacaagattt
     2041 gcacaatttc caaaacataa gcataattat atagaattta attatgttta tagaggaaag
     2101 ttagtacaaa ctatagatga atataaaatt aatttaaaac aaggagaatt aatattttta
     2161 aatcagcatg ttattcatga aatagaagct agtgacgaag aagatataat aattaatttt
     2221 ataataaaac cagagttttt tgattatatt atatctttgt tggaaaatga taataaaata
     2281 atgaactttt taatgactac attatatact aattataatc ttggagaata tatatatttt
     2341 aaagtatctg agaaagaaga gattcaagat ataatagaaa aaattataat agaattgtat
     2401 gaaccaagtg tggttaataa ggtaaagatt aaattattag taggattatt attagtagaa
     2461 ttagttaaaa attctgaaga tgtagaaaat catgcagtag ataattatga aaagatgatg
     2521 attatagaaa tactaaaata tattgataag gactacaaga aaggtagttt atctgaaatt
     2581 gcaagtaatt tgaatcaagg tgattataaa ataagtaaac tagtaaaaaa acatcttgga
     2641 tatactttta aagatttagt gcaagaaaaa aggttaagta aagcatgtga attattagta
     2701 tctactaatt tatcaatagc tgaaattata gaaaatgtag gttatgaaaa tttaacttat
     2761 ttttataaaa tatttaaaaa taagtatggt attacaccaa aagaatacaa aaaaaatata
     2821 aaaaatggtc aatagtaaaa ttagaatcta taaaatagat tcttttttat tattaaataa
     2881 accattttaa tagctctgaa gatattatat tttgaaaatt attattgaga ataaagttat
     2941 attgcaaatt aggttaataa atatgacaaa tttagatatt aaatgaatat actaacatct
     3001 tgtataattc aattaataaa taaatctaag gaggaaaagt cttgagatac tatttagcaa
     3061 ttgatatagg ggcatctagt ggaagacata ttatctctta tataaataat ggaaaattgg
     3121 aaatagaaga agtatataga tttaagaata atttgattaa aaaagatggt catttttgtt
     3181 gggatatatc aaagctattt tctgaaataa aaaatgggat aaaaaaatgt ataaaaataa
     3241 ataaaattcc agtaagtgtg gctatagaca catgggctgt agattttgtg ttacttgatg
     3301 aaaaagacaa tatattaggt aactgtgtat catacagaga taatagaact gatggaatta
     3361 tggaagaagc ctttaaaata attgataaaa aggaactata tttaaaaacg ggaatacaat
     3421 ttcaaaagtt taatactata tatcaattat tatcaataaa aaatcaacag ccagatttat
     3481 tagaaaaggc aaaaagcttt ctaatgattc ctgattattt taacttttta ttaactggga
     3541 aaaaagttac agaatataca aatgcaacaa ctacacaatt agtaaataca acaacaaata
     3601 attgggatga agaaataata aataaacttg gatttgacaa gatgttattt gctaaaataa
     3661 aaactcccaa aacaatacta ggtagtttaa agaaagaatt agtagaagag ttaggatgtg
     3721 atttagaagt cattttacca gttactcatg atacaggttc agctttcatg tctactcctg
     3781 taaaaaatag aagcatttta ttgagttcag gaacatggtc tttattagga gtagagttag
     3841 aaagaccaaa gtgcaaatta gaggctttag attataattt tactaatgaa ggtggatatg
     3901 aatatagata tagattttta aaaaatataa tgggtttatg gatgatacaa gaagctagaa
     3961 agtgttatga cagtaagcac tcttttacag aactagtaga gcatgcaaga ctatcagaag
     4021 gatttaaatc aatagtagat gtaaatgatg atagattttt aaatcctgaa aatatggtac
     4081 aagaaataat aaaatactgt atagaaacta atcaaacaga accacaaaca gttggagaag
     4141 tagcatattg tatttttaac agtttagcaa aaagttatag taaatctata aatgaaatag
     4201 aagaaatcat aggagaaaaa ttagaaacta taagtgtatt tggtggagga tgtcaaaatg
     4261 aactgttaaa tgaacttata gcaaaagaaa gtggtaaaaa ggtattagca ggacctgttg
     4321 aagctacagc attaggtaat atagtatgtc aattaattgc taagaatgag ctaaatgatt
     4381 tagaacaggc gagagatata ataagaaatt catttgatat aattcaatat aattaatctg
     4441 aaaaaggaga taagtgatgg aattaaagca aaggtatgaa gtagctaaaa aagaatatga
     4501 aaaatgggga ataaatgtag aggaagtatt aagagtttta tctaaagtta aaatatctat
     4561 tcattgttgg caaggtgatg atgtaacagg gtttgaagga aatcaacaaa gactatcagg
     4621 aggaattgca tctacaggaa attatcctgg aaaggctaga aatcctcagg agttaagacg
     4681 agatttggat aaggctttaa gtttaatacc agggaaacat aaagttaact tacatgctat
     4741 atatgcagaa actggtggaa gctttgtgga tagagatgag ctaaaaccag agtattttga
     4801 aaattgggta aaatgggcta aagaaagagg attgggatta gattttaacc caacaatatt
     4861 ctctcatcca aaatcaagtg atgggttaac attgtcacac ccagataaaa aaatacgtga
     4921 tttttggata aagcattgca tagcttctag aaaaataggc gaatactttg gaaaggagct
     4981 tggtcagact tgtttaacaa acatatggat accagatgga tacaaagata taccaagtga
     5041 tagattaggt cctagaagac gcttaaagga atcactagaa gaaatattaa aggtagagat
     5101 aaacagagaa tataatttag attgtgtcga atcaaaagtt tttggattag gtgtagaatc
     5161 ttatacagtt gggtcaaatg agttttactt aaattttgct agtaaaaaca acataatttc
     5221 attattagat acagggcact atcatcctac agaacttgtt tcagataaat tatcatcaat
     5281 gctattattt tcagataaag ttgcacttca tgtaagtcgt ccagtgcgtt gggatagtga
     5341 ccatgtagtt atattagatg atgaactaaa agaaatagcc aaggaaatag taagaaatga
     5401 tgctttggat aaagtaataa taggactaga cttctttgat gcaagtataa atcgtatagc
     5461 agcatggata attggaacta gaaatatgat aaaagcattg ttatcagcta tgttaatgcc
     5521 tcatgaagaa ttaagaaaat tacaagacga aggcgatttt acaaaaagat tggctataat
     5581 ggaagagttc aaaacatatc caatgggaga catatggaac tattattgta aaattaataa
     5641 tgttgctgtt aaagaagatt ggatagaagt agtaaaagag tacgaattaa cagaattatt
     5701 aaatagaaag taggtaaggg tatatgtcta taatggaaat gaactttatc aaagatttta
     5761 tgaaaataac ttatgatgct tggttaaagg gatggcatga gcgtaatggg gggaatataa
     5821 catatagatt aacacctgaa gaaatatctg gaataaaaga atttataaca gaagaaatag
     5881 aatatattcc aattggtgta acagtcgaaa atttagctaa tgaatatttc ttagttacag
     5941 gaagtggcaa attcatgaga aatatttcta taaatactgt tcaaaatgta ggaattgtta
     6001 aaatagatga aaaaggtgaa aattatgcaa tagtttgggg attagataag gctaaaccaa
     6061 caagtgaatt tccatctcac ttaatgagtc attctataaa aaaagacaaa acaaatggat
     6121 tacatagagt aataatgcat tcacatacaa ctaatctcat agcattaact tttatactgc
     6181 ctcttgaggg taaagtattt acaagagaat tatgggagat ggctacagaa tgtccagttg
     6241 tatttccaga aggaattgga atcgtacctt ggatggtgcc aggtggtata gagatagcaa
     6301 aagctacaca aaatctaatg gaaaaacata acatagtaat ctgggctcat catggaacgt
     6361 tctgctcagg agaaactttg gacttaacat ttggtcttat ggatacagta gaaaaatcgg
     6421 ctgagatatt agtaaaagta atatctatgg gagggaaaaa acaaacaata acaggagata
     6481 actttagaga cttatcaaaa aattttaagg tttcaatatc agaggattat ttgtactaga
     6541 taagataaaa gataaacaaa gctatgataa cttattatgt gcaattaata aaacactatg
     6601 agagaggagg tgattaaaag atatagaaag taaattcact taagaaaata gtttaagaat
     6661 aaactggagt ttataataaa atattc
//
LOCUS       DAEPXW010000156         6490 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.160, whole genome shotgun sequence.
ACCESSION   DAEPXW010000156 DAEPXW010000000
VERSION     DAEPXW010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6490
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.160"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(26..1393)
                     /locus_tag="KRM55_003472"
     CDS             complement(26..1393)
                     /locus_tag="KRM55_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1595661.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(1643..2107)
                     /locus_tag="KRM55_003473"
     CDS             complement(1643..2107)
                     /locus_tag="KRM55_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBH1595662.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(2112..2741)
                     /locus_tag="KRM55_003474"
     CDS             complement(2112..2741)
                     /locus_tag="KRM55_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH1595663.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKLKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(2775..3662)
                     /locus_tag="KRM55_003475"
     CDS             complement(2775..3662)
                     /locus_tag="KRM55_003475"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBH1595664.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(3691..4929)
                     /locus_tag="KRM55_003476"
     CDS             complement(3691..4929)
                     /locus_tag="KRM55_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595665.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(5313..6455)
                     /locus_tag="KRM55_003477"
     CDS             complement(5313..6455)
                     /locus_tag="KRM55_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH1595666.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
BASE COUNT         2316 a         1084 c          666 g         2424 t
ORIGIN      
        1 tcataaaaaa tttatattgt atatcttatt cttttattgc tttaggtttt gatagaaaac
       61 atttataaaa tataaagaaa gaaattgctg ttatagtagc agctgttata tctgcaactg
      121 gctctgctaa aattactgca aaaagttttt cattaaagaa tgttgggagt ataaatatta
      181 aaggtattaa aagtacaatc tttctaagta gagctaaaac caaagatatt gttgcttttc
      241 caagtgctaa aaatgtctgt tgacaagcta tttgaatccc aaacataaaa gcaccagcaa
      301 aatatatttt tatactccaa ctagtcatac taagtaactg cggattctta ttaaatatac
      361 taacaaaaaa tgcaggaaat atcattaata aaagccataa aatagtagaa tatgtaaaac
      421 atgacaacaa acacaactta aatgtctttt ttactctatc aagttgacct gaaccataat
      481 tataacttat tattggttgt gctccttgtg taacccccat attaggaagc ataagaattt
      541 gcattatact gctcattata gccattgaac ctactgctaa atctcctcca tacatttgta
      601 atttactatt taaggctata agtactaaac tttctgtaga ttgcattata aatggagaga
      661 ttcccaaacc aagcactggt aagatgatac ttgcttttgg tatcatatac ttctttttta
      721 ttttaagtat acttttcttt ccaaagagaa acataagtac ccaaatagca gaaacgcctt
      781 gtgcaattat agtagctaat gcagctcctt ttacacccat attaaagcca aatataaaaa
      841 tcgggtcaag tattatgttt attaaagcac ctatagcaac tgtcatcatt ccagttgtag
      901 caaacccttg ggtatttata aaagtattca tacccattga aatctgaaca aacactgtac
      961 ctattaaata aatatttaaa tagtccattg aatatccaat tgtagattca cttgctccaa
     1021 acatccaaag taaaggctct tttccaatct taaaacctat agtcaaaagt attgctaaaa
     1081 tcaccagtac agaaaaactg ttactcatta ttttctctgc ctcatcattg ttttgctcac
     1141 ccatttttat agcagctaat ggacctcctc ccataccgat taaataacta catgcagtta
     1201 ttataattat tattggaaat gccactccaa caccagccat agcaacttct ccattttcca
     1261 ttctaccaat aaaaatccta tcgactatgt tgtataaaac atttacaatt tgtgcgataa
     1321 tagcaggtgt agcaagttta aataataatt tacccacact ttcactacct aagttagtgt
     1381 ttgaattttc cattttaaaa cctcctcaat ccaataatta aaatgtatca ctaaaatttt
     1441 attctatata aaaatttcat tttattagca gacaaattta gagtactttc cctacaagta
     1501 atactatact atatttcttt tgccatagta aacattttag aactaactga agttaaatac
     1561 tttatctcat tttttattta ttattaaaaa tttttcacac atactcataa aaaaactatc
     1621 caagtatatt acttagatag ttttatatta tatgtaaaga aagagctgaa actataaccc
     1681 ctgataacaa attaccaaga aatactccca taaaagcatc ttttattctc atttttaata
     1741 tggaagctat agcagatgca gtccatgttc ctgtagttgg cagtggtata cctacaaata
     1801 gtattatacc aattatcgaa acacttttta atttcttcat tcttgagttt atttttctat
     1861 caattacatc agcaatccct ttaaatagtt tcttccctct taaaaattgt aatacatgtc
     1921 tgaatgtcaa tatcaaggga atcgatacca atgtagaacc tattacacta aatacataaa
     1981 cccatatagg atttaagccc attgcaatac ctataggaat ggctcccctc aattctgtta
     2041 caggaaccat agataaaatt aatatgtgta aatatcccaa actattccct cctattctaa
     2101 gtgacattaa gttatgaatt tatttgctct ataacctcac catccttttt actaactaaa
     2161 aatgcatttt tagtcaatga aagcattggt aaatcactct tagagtctga atatgcatat
     2221 gaattttcat aatcaatctc tatcccaagt ttacctaata cagcctttat tctttttaat
     2281 ttttcaattc ccttacaatt ttctccaatg aattgatttt tatatcttga attttcataa
     2341 aaaaactccg tgcctataac ctcgtctgca agaccataat acttaaaata tttcatatat
     2401 gcatatggag atgcagttat cataattata acattatctt cttctttatt tttgtaaata
     2461 acctttttca tagattcgtt aatttttttc attatgcaat catcaaaaaa cttttttaaa
     2521 tcttcttcac taaaatctac tattggataa aagattgcct cttttgcctt cttcaaaggt
     2581 atcattctaa ttaaatacat aaatagaata aaaataatgt atggcaactt tataatagtt
     2641 ttaaaggttt tattttttaa agagtaaata aaaaaatcta tcatgctatc agtatttata
     2701 acagtataat ctacatcaag taataataca ctttttttca taagtatttc cccatcctat
     2761 cactaaaaat atcactaaaa aatcaatatt attaaacatg taattatcca taagattacg
     2821 tttattttta aagcattatc ttttaggaca atatcagtag gattattttc atttgtagtg
     2881 ttaattatat aattatatct aagtacacca taaactacaa atattgttgt aaatatcata
     2941 tgtggctttt ctggattact tgtagaatac aatgcataac atacaattgt agaacttaat
     3001 ataactatca tcatttgatt tagattttct atgtcataat cttccaatat ttttctatgt
     3061 tcaactgcat catctcttag agtttctatt tcttttttac gttttccaag agctaagtac
     3121 agagataaga aaaatgtaca taaaattatc caatttgata aactaacact tatggctaca
     3181 catcctgcat aaaccctaag tataaaacca agagatattg aaaacacatc taatagtatt
     3241 atattcttta gtttaagaga atataatata ttgtttatca aatagagact gagaattata
     3301 gaaagattaa aactaacaac tgttgataaa cagactgaaa ttaaagctaa tactacaaat
     3361 agtatattag cacttttttt gcttattctt ccacttgcca ctggtctatt acatttttta
     3421 ggatgttttt tatctttatc catgtctata gcatcattca gtgcatatac tgatgatgac
     3481 attaggcaaa aacacacaaa cgcaataaac gtatttaaaa ataaatttat atttagtatg
     3541 ttgtttgaaa aaattatagc tgaaaataca aagaaattct ttatatattg ctttattctc
     3601 attaacttta tataatctga aattttagta agaagcctta tacttgtatt ggtctgtttc
     3661 ataaacttac taccctttca atattatttt ttaaacagga tatgatttta tccctatgtt
     3721 taaaatttct ataaatccat tgacattact gattactata gtaaccaata acagcgatag
     3781 aaatatatta tacatattct tttcattttt tctaagcgct ttcgtaaagt aagccaataa
     3841 aattataact gcaaaactaa aatttatagc cataatactt gaattgacta gattatatcc
     3901 tactatacca tgtaaagtta gattgaatat aattattccc atacatagct taggaactct
     3961 tttttctgaa ttttcaataa ctgataaaac acaaaaacat aaagctaata atgtaagaat
     4021 tactggtatt gtagcaactt ctccattttg caaaaataac ccttttttaa tgcttgctcc
     4081 aggaaaataa aaaaccgaat acaataatct ctctataatc attgcaatct tttccaaaat
     4141 tggttctcca cttataaatt tcgtatcata ctgtattaca tttccaaggt tcataaaact
     4201 ctcataagac ttcgttgaaa ctacacaaat atatgccatt aggataaatg taattaaatg
     4261 ttttaacatt tttcctattt ttaatttaaa ctcaaatatc atattaaaaa aatacaaata
     4321 tatattacta atagttattc caaatagagg aatagctgct aattctacta aataagaatt
     4381 ttttcctttc atcttatttg caataactat gaaaaatatt aatgaaaatt ggctatatat
     4441 aaatctctct acatttaaag tcataaatag ctgtggaaaa gaaaatatca ttatcatagt
     4501 aagtaaaatt aaagttaatc tctgcatttt tatcttttta atatgattaa agactaaagt
     4561 tattgacata gcactagtta ttatttgtag acaaattagt ccaaacccat aggcactatt
     4621 aaaatctgtt gtcccaggat ttgctattga agtacaaaat aggtatattg gatatgcaaa
     4681 aattgatata attgctgaaa acaatatgtg cttactattg tcttgactta tagcaaatac
     4741 atttaaattg aataaaactc ctgtatctgt atctaacaat acatcataag tattgtttaa
     4801 atcataaaat atagtagtct tagaaaaaaa tatcttagtt attattaagt aagttattac
     4861 aactaatata aacaaaaaca tctcgttttt atattttaat attttactca tcaatatatc
     4921 accatccatt cattatatag gatttgctga cacctacaat ttattcctta tatttaatag
     4981 ccatcttcat aatgttctta cttgttttat tgtaattgaa taactcttta tttacaacca
     5041 caatatttac tttattgatg ttataatcag tcaagtattg tttatataac atagattagt
     5101 gttgtataaa atgagaattt gtaagcaata ttaatgtaaa atatttgaaa aactttatat
     5161 aaaaatatac aatgttgctt atggaattaa actataacaa attaaagcat aatttaagga
     5221 gacaaaatta taatctgtct ccttaaatat taaaactata ttttaaaaca ttactaaata
     5281 ctatacaaat ttcaaatata gtataaaatt aattagactt taacactatt agctccatct
     5341 tcttcccatt ttttaatttc ttttaatcta tctattatag gtaaatgctg agtacattca
     5401 acttcacatt ttccacaaga tatacattct ttagcttttg ccttactatt cattgtgtaa
     5461 ttccaatgtc ctaagccata aactaacttt gtcatttctt catcactctt tttaaacatc
     5521 tgcttttcat tataaaaaag catataggct ggggtattaa taccttttgg acatacttta
     5581 caataaccac aacctgtaca tatttcgttc atattcttat ttaatctagt ctcaatatca
     5641 tgtatatcct catctgaata aattctattt tcgtctgcaa ttttacatgc atcatctata
     5701 tcttgttttt tattaaaccc tatcaaagat atacttattt gtgaaattcc tatgttgaat
     5761 cttaaagctg attctatagt actttcgcca tcttttgata gaaaagaaag ttctttatta
     5821 tactttggaa tagttccacc acttaatgga ttcattgcca caacaccata tccattatca
     5881 acagcatatt tggcaccttt tagcctatat ggaaagttta atatatttat tcccatagtt
     5941 acaccttcaa acttattttc acttagaata tctataacct catctcctgg ttgatgagat
     6001 gaaaatacta tatggtctat caatccttct tctttacatt tcaataatcc ttcatattga
     6061 cctccaggtc tcattgctag ttcgtaatgt tccatctttc taatattcca aacatgataa
     6121 aaatttattt tagatacgcc taatcgttct attgattttt ttacagcctc tatagctttt
     6181 tctgatgtat cacatgcttt tggcttttct ttagttgata cataaaaatc ggtcttacct
     6241 tcctttatca tttgtctaaa ggctagtcca aatatatctt cacttctgtc atcacaatac
     6301 cctggtgctg tatcaaagta attaatacct ttttcatacg catatttgac taaatcagca
     6361 ttttcttgat tacttttttc taaatcaaac cttaatcctc catagccaac tactgaaacc
     6421 attttccctg tctttccata ttcaacgtat ctcattgtaa attcctcctt agatatatta
     6481 agacttaatt
//
LOCUS       DAEPXW010000157         6199 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.161, whole genome shotgun sequence.
ACCESSION   DAEPXW010000157 DAEPXW010000000
VERSION     DAEPXW010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.161"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            433..1647
                     /locus_tag="KRM55_003478"
     CDS             433..1647
                     /locus_tag="KRM55_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595667.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLNQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHENLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(2067..2588)
                     /locus_tag="KRM55_003479"
     CDS             complement(2067..2588)
                     /locus_tag="KRM55_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595668.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHEQRKSSLQAEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            2944..3741
                     /locus_tag="KRM55_003480"
     CDS             2944..3741
                     /locus_tag="KRM55_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH1595669.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            3851..4441
                     /locus_tag="KRM55_003481"
     CDS             3851..4441
                     /locus_tag="KRM55_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBH1595670.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            4507..>6199
                     /locus_tag="KRM55_003482"
     CDS             4507..>6199
                     /locus_tag="KRM55_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH1595671.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLMEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKL"
BASE COUNT         2515 a          615 c         1047 g         2022 t
ORIGIN      
        1 ttatttatat ataatatttg aaaagtggat tatgtatatg caaagtagaa aagagagagc
       61 ccagaagtga ttttttgcta taatgccatt tattgaatag gtgggtgtta ttataaataa
      121 attattaaca ctcagtatta ttatcattgt atatggaatt tattttattt aaaattcctt
      181 gaaagtttaa atatagtaag ttgtagtaaa gagaaaatat aaatatttaa atgctattta
      241 atgtgaatct attaattagg ttatacttaa acttaattaa tagattttat atttcaagac
      301 aatgagatag ggttttagat taaaatataa ccaatggtta aattacagac attttgttaa
      361 ctttccctcg atttactagt aaatattttt tttatatact taaattacaa cagatgtact
      421 agggaggtat atatgcaaat taaaataggt aaagtcatac agtgtcttag aaaagaacga
      481 aatttaactc aagaacaatt agcaaagttt ataggtgtgt caacaccagc agtatctaag
      541 tgggagagtg gaaattctta cccagatata gaattattgc ctttattagc agactttttt
      601 aatgtgtcta ttgataagct tttaaattac aagattgatt taagtgaaga agaagtaatg
      661 aaaatttata aagaattaga atcaggcttt gctagaattg aaattgattt atcaacagaa
      721 gaaccaaaag aagaatttag acaagactta gaatctgtaa aaaagctttc caatatgtat
      781 atagagaagt atcctaaaag ctatttattg aagctaagga tatgttcgct gtatcagatg
      841 tattcatata aatttggtaa gagtgaactt aatgacagag taaaagaaac aacgaatatt
      901 cttgaagata tagtgagaaa tacagatgat atccaaataa aagaaacagc tcttattata
      961 ttatcaaacg catattgtat gttggaggat tatgaaaagg cagagttgta tttaaatatg
     1021 atacataagt caatagggga tacaagtgtt aatttagcta tgatatattt aaatcaaaat
     1081 agacttgaag aagcagaaat attgcttcaa aataaattgt ttagtaatgt atttaatata
     1141 agcatggatt gtaagggaat aattaatgta tacaaaaatc aatacaagga attaaagaaa
     1201 aaattggaga atagaaattt taataaaaat gcaattgaga gagaaatgga gtatataaaa
     1261 aataagttgc tggggtatgc aaatctttct ttagaaataa aaaaaatgct cagtgaagat
     1321 aaaggtgcat tttttagtat gtatatggat tatatggaat tatctctaat ttttttattt
     1381 tttaacatga aagaggaagc aaaaaaagcc ttatatagtc taaaagaaat attagaaaaa
     1441 tatcctatac atgaaaattt ggatgtaagt caaatgagat tttttgataa ggtagagtct
     1501 aaaaatttat atacttttaa tatatataca aacttgttaa ttgtacttaa tgatgatagt
     1561 tataatgagc ttagagaaga accaattttt aaggatgtaa ttgaaaagat tttagatatg
     1621 gaaaaaatgt tgaaaaataa agaataagta aaaatttaat ataggactta aagattaatc
     1681 aaattaaaag aaagtgtttc aaaataaaaa tttgaatcac cttttttgtc ggtcttaaac
     1741 agttatttag aaaaatagag gtttcaaaat agaaatctga attatctgta ttattacaca
     1801 aaaatagaaa cctaaattta taaaaataga ataaagtttg ttatataaaa tgtaattttg
     1861 tctataaaat ctcacttgtt ttcttaactt taagcgtgaa aaagagaatg tatcatgaat
     1921 tttttagttc atgatgcatc cttctttgta tgaaatccaa tatatcttta ttatttaaac
     1981 aatggaaaag agccttattt ctattttgag acatctcttt tatttaatta tgaagtttta
     2041 tacagttcaa taaataggaa ttatatttag aaactcatga cattatttct tagatagtga
     2101 ttaaatttat catattccat tttagataac ttttctgggt aagacattac aatcaggtta
     2161 tgcccattaa atttttcatg gtatggtgga tgaatgtgtt cataattatt tgtcttatat
     2221 tttactcttt catagaacgc cttgcgataa attgaaatct catcaattgg aaggtcaatt
     2281 tctaaaataa tagtttttcc tttcttattt aaaagctcta acgctctttg cccatatcta
     2341 ttattgcgca tttctggaaa aatgcagaaa tgttctacat agataaagtc atctgtttcc
     2401 caacataaaa ttatgccgac aaactggttt ttatcataaa ttaaattgaa ttgatattct
     2461 ttatttttca aaatttctgc ttgcaaagaa gattttcttt gttcatgaaa tgggaaacta
     2521 attttatata attccatagc cttgtaatat aatttatttt cactggttct taaccgttca
     2581 aatttcactt tactcctcct aatcacgaaa atttcaattt atttatgagt tcattttacc
     2641 atagtcagta tttgcataca atgtgtttta agttgagtgt catttctttc ttttatttat
     2701 gtttatatct catagactaa gagataatta cttaagacat aactaaaaac tattatatta
     2761 agctttgata atctaaaaac agtatattta tggacttttc taggtctaaa agtaatctta
     2821 ataattttag aagttacaaa aaagttacat aaatttggaa agctataata tacatatata
     2881 atataaggtt aaaactgtaa tgaataatat taatttaaaa tttgaacatg gaaggagatt
     2941 attatggaga aaagagaaaa gaggataata atatcatctt tattaagtgt atcaatttta
     3001 atgggtttgg taagtatata ttctatatta aataaagaag acataatttt aactgttaag
     3061 ggtcaagagc aaaaagtatc ttcctttaag aaaacagttg aggaactttt ggatgaacag
     3121 ggtgtaaagt ataattctga agataagatt aatccaagtt tagatacaga actaaaagat
     3181 gatatgaaaa taaaagttgt taaggtaact aaaagtaaaa aagaagagat tgaaaaaatt
     3241 ccatttgata caaagcatgt aaatgatagt aatttgttaa aaggaaaatc taaagtttat
     3301 caagaaggtc aagaaggaga aaaaaaacta gtctataatt taacttacca tgatggaaag
     3361 ttagtcaaaa aagtcttatc aaaagaagta atatctaagg agccaactac aaaaattata
     3421 aaatatggaa ctaaagaaaa agtactaata gcatcaagag gagcaaatat aagaggaggc
     3481 aaacatatga aagtggttgc cactgcatat gcaggagata caataacatc tactggtaca
     3541 actccaagat ggggtgttat tgcagttgac ccacgtgtaa taccatatgg aacaaaagta
     3601 tatataccta aactgggtat gacttttgta gcagaagatt gtggaggtgc aattaaaggt
     3661 aatagaatag acatttttat gaacagtgaa ggaaaagctt caaattgggg aaggaaaagt
     3721 atagatatat atctacatta aattagtgaa tagaataact ttacttgaag gacaaaaaag
     3781 tataaaatat gaattaacta aactgttaga ttattcttaa aacataaaaa tatatctaag
     3841 gggggataag atgaaaatag tctgcttagg agacagttta acgtatggat ttggagtatc
     3901 acgaagtaat tcatggacaa acattgtaaa taaagagact cgattagaaa tagtaaataa
     3961 gggtataaat ggtgatacaa caagtggtat gttagctagg tttaatgaag atgttgtaaa
     4021 aaactctcct gatatagttt ttataatggg tggcaccaat gattttattg ctggtgcggg
     4081 aaatgaaatt attaattcta atataatggc tatggtgcat cagtcatatt caaaaaatat
     4141 tatacctata ataggtatac cattaaaacc agatattcca aatgttaggg aagattggag
     4201 ttgttttact gattttaata tagtatctca aaacttagaa tcatatagtt attggataaa
     4261 aaaattttgt atgacattta atactaattt cgtagatttt tattcagaat ataataaaaa
     4321 tatggaacta gaaggatata aaaaattata ttttgatggg ttacatccaa ccaaagaggg
     4381 tcatagaata atggcagaca tttttattaa ttcaattaat aagtatatag aagagttata
     4441 gattacatta aaatgcttgt ttatgcgtca gttgcaataa atacatacag tagagagggg
     4501 tttattatgg attatactaa aacttatgaa gagtggataa agggttcata ttttgatgaa
     4561 gatacaaagc tagagttgga gaatataaaa aataatgaaa aagaaataga ggatagattc
     4621 tataaggatt tagaatttgg gactgcgggt cttagaggaa taattgaagc aggaacgaat
     4681 agaataaata agtacacagt tagaagagct acttttggat tggcaaacta tatattagaa
     4741 aacacaacaa aagaagaaac aagtagagga gtagtaatag ctcatgataa tagacacaag
     4801 tctagacaat tctgtataga atctgcaaat actttggcag catgtggtat aaaagcatat
     4861 atatttgata gtttgagaac tactccagaa ttatcttttg ctgttagaag cttaaatgca
     4921 atcgctggta tagtcataac agcaagccat aatcctccag aatataatgg atataaggta
     4981 tactgggaag atggagcaca agttatgcca gagattgcaa atgcaataac agagaaagta
     5041 aatagtatac atgattatag tacaatacca accttaatgg aagctaataa aaatttggta
     5101 gttttgttgg acgaatcaca agatactaaa tttatagaag cagtaaaaag ccaaattata
     5161 agaaaagatt tagttaaaaa tgtaggtaaa agctttaaga tagtttatac acctctttgt
     5221 ggaacaggga atgttccaat aagaagagca ttgaaagaag ttggttttga aaatataatt
     5281 gtagttccag aagaagaaaa tccagatcca aattttgcag ggcttgatta tccaaatcca
     5341 gaagagaaaa aagctttaaa tagaggtata ttactcgcaa aagaaaaagg agcagacctt
     5401 gtaatagcaa ctgacccaga ttgtgataga gtaggtgtag cagtaaaaac tactacaggt
     5461 gagtatgctt tacttacagg aaatcaaatt ggtggtatgc tgacacatta tataatagaa
     5521 ggattaaaag aaaataataa attaaaagaa aatcctacaa taataaaaac catagttaca
     5581 tcagaatttg gagcagatat agctaaagca aataatgttg atgtattaaa tgttcttaca
     5641 ggttttaaat ttattggtga aaaaataaaa ttatttgaac aaaataaaaa tagaagttat
     5701 gtatttggat atgaagaaag ttatggttac ttagttggga ctcatgctag agataaagat
     5761 ggtgtagttt cttcattgtt aatatctgaa atggcagcat tttactattc aaaaggtatg
     5821 agtttatatg atggtttaat agaactttat aaaaagtatg gatttttcaa agaacagact
     5881 atatctttga ctttaaaagg tatagaaggt gtagaaaaga taaaagaaat aatatcttat
     5941 tttagagaaa atcaaattga ttatataaat agtattaaag tagttgataa aaaagattat
     6001 aaaaatggta tagataatct tcctaaatct gatgttttaa aatacttttt ggaagatgaa
     6061 tcttgggtag ctataagacc atctggaaca gaaccaaaac ttaaatttta catagctgta
     6121 aaaggagcta gtgatattga agcagataaa aagattcaag gtttgaaaaa gtatatagat
     6181 gacatggtcg aaaaattaa
//
LOCUS       DAEPXW010000158         6182 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.162, whole genome shotgun sequence.
ACCESSION   DAEPXW010000158 DAEPXW010000000
VERSION     DAEPXW010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6182
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.162"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            180..1202
                     /locus_tag="KRM55_003483"
     CDS             180..1202
                     /locus_tag="KRM55_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1595672.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            1262..2269
                     /gene="gap"
                     /locus_tag="KRM55_003484"
     CDS             1262..2269
                     /gene="gap"
                     /locus_tag="KRM55_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH1595673.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            2491..3693
                     /locus_tag="KRM55_003485"
     CDS             2491..3693
                     /locus_tag="KRM55_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBH1595674.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            3719..4462
                     /locus_tag="KRM55_003486"
     CDS             3719..4462
                     /locus_tag="KRM55_003486"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBH1595675.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            4471..6003
                     /locus_tag="KRM55_003487"
     CDS             4471..6003
                     /locus_tag="KRM55_003487"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBH1595676.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
BASE COUNT         2458 a          720 c         1251 g         1753 t
ORIGIN      
        1 aaaaaatact gtgatttgaa aatggtggag aaatatttta taaaataaaa aaataaaaaa
       61 gtttttgaaa aactattgaa atctatacgc aaatcctata aaataaaaat atcttgtggg
      121 acttaaataa acactaggga caaaaaaagt cccggaagga aagcaataag gagtatgtta
      181 tgaagaactt attagaaatt caaaagaaat tgattccaca ggcaattgaa cttatggaaa
      241 gaagatactc tattttaaga caaatatctt taagtgaacc aataggtagg agaacattat
      301 caaatgtatt agagattagt gaaagaataa ttaggtcaga aactgagttt ttaaaagaac
      361 aaggacttat agacgtagct gtatctggga tgactatcac taaagaaggt tctgatttgt
      421 tagataaact taaggacatc atgagtgaca tcatgggatt gtctaagtta caagatagag
      481 tcagagaaaa gcttggaata aaaagggtaa tattagttcc tggaagctgt gatgaaaatg
      541 gaagtttatt aaaagatgta actagatatg gatgcgaata tttcttaggc attttaaaag
      601 atggagatat cgtttcaata acaggaggaa gcactatgtt ggagttttca aacgttatta
      661 aaactgataa gagatatcca aactctacaa tagttccagc tagaggaagt atgggaactg
      721 atgtagagat gcaatctaac aatatagttg cttcaataag taagaaatta cattctaatt
      781 gcaaactttt acatatacca gatgagttgg atgaaagtgc aatgaaaact cttagccaag
      841 tgccagagat taagacaact ttggagtata ttaaaagaac agacatttta gtttttagta
      901 taggtagagc agatgtcatg gcaaagagaa gaaaacttcc agaagacaag gttgatgaga
      961 tattatctaa aaatgcagtt ggagaagcat ttggatatta tttcaacaaa gatggagaaa
     1021 tagtttacaa actgaacact gttggaattg atttagaaac agttaaacaa gtaaaagaaa
     1081 ctattgcaat ctttgcaggg actgaaaaag tagaagcctt attagctata tcaaatatgc
     1141 ataaaaacat ggttcttgta acagatgaag aaagtgctta taagatattg tcattattat
     1201 aaaagtcaag acctagcaca gagctagaaa acatacattt actttatagg aggtagcgaa
     1261 aatggttaaa gtagctataa atggatttgg aagaatagga agattagcat taagaaaaat
     1321 gatggagcaa caagataagt tcgaagttgt tgcaataaac gacttaacag acgctaaaat
     1381 gttagctcat ttatttaaat atgatacagc tcaaggaaga tttaacggag aaatagaagt
     1441 taaagaaggt gcttttgtag taaacggaaa agaaataaaa gtaacagcag aaagaaatcc
     1501 tgctgaccta ccatgggctg aattaggagt agatatagta ttagaatgta caggattctt
     1561 tacatctaaa gataaagctg aagctcatat acaagcaggg gctaagaaag ttgttatatc
     1621 tgcaccagct actggagatt taaaaacaat agtattcaac acaaacagtg acatattaga
     1681 tggttctgaa acagttatat caggagcttc ttgtactact aactgtttag ctccaatggc
     1741 taaagtatta aatgataaat acggtataga aaaaggatta atgactacta tacatgcata
     1801 cactaatgac caaaatactt tagatggtcc tcatccaaaa ggtgatttaa gaagagctag
     1861 agctgctgct ggaaacatag ttccaaacac tacaggagct gcaaaagcaa taggcttagt
     1921 aataccttca ttaaaaggaa aattagatgg ggcagcacaa agagtaccag ttgtaactgg
     1981 ttcaataact gaattagttt gtacattagg aaaaaatgtt acagttgaag aaataaatgc
     2041 agctatgaaa gaagcttcaa acgaatcttt cggatatact gaagaaatgt tagtatcttc
     2101 tgacataatc ggaataagct acggttcatt atttgacgct actcaaacaa aagttatgga
     2161 agtagatgga aaacaattag ttaaagttgt ttcttggtat gataatgaaa tgtcttatac
     2221 ttctcaatta ataagaactt taggatactt tgcacaatta gcaaaatagt cagttttgag
     2281 aaaatagaaa agtagattga caaagtccga gtttgtagtt taatactacg gactcaggac
     2341 tttttttaag aaaaaatata taaaatacac ctaaataatg ttacatacta tatataaaaa
     2401 tatgataata tgatatattt aatagggtaa aagtatgtac tatattatac ttggcaataa
     2461 aaaattactt tattaaaagg agagatattt atgtcaatgc ttaacaaaaa aactatagaa
     2521 gatattgatg tgtgcggaaa aaaagtatta gtaagatgtg actttaatgt gccattacaa
     2581 gatggtgtaa ttactgatga aaatagattg aacggagctt taccaactat tcaatattta
     2641 atttctaaag gggcaaaagt tatattatgc tctcacttag gaaagccaaa aggagaagct
     2701 aaaccagaat tatctttagc accagtagca aagagattat ctgagatgtt aggaaaagaa
     2761 gttgtatttg cagcagacga taatgttgta ggagaaaatg caaagaaagc aactgaaaaa
     2821 atggaaaacg gagatgtagt attattagaa aatactagat atagaaaaga agaaactaaa
     2881 aacgaagaga atttctctaa agaactagca tcacttgctg aaatatttgt aaatgatgca
     2941 tttggaactg ctcatagagc acattgctca acagttggtg caggcgagtt tttacaagag
     3001 agagtttgtg gatacttaat tcaaaaagaa ttaaaattct taggagaagc tgttgcaaac
     3061 cctgtaagac catttacagc tatacttgga ggagctaaag tttctgataa attagctgtt
     3121 ataaacgaat tattagaaaa agttgataat ctaataatag gtggaggaat ggcttataca
     3181 ttcttaaaag ctcagggtta tgaagtagga acttctttac ttgaaataga taaagttgaa
     3241 tatgctaaag aaatgatgga aaaagctaag aataagggtg ttaacttatt attaccagta
     3301 gacgttgtta tggcagacca ctttgcacca gatgctactc caatagtaac agaagatgct
     3361 aatgtaaaag aagattacat gggactagat atgggaccta agactatagc aaactttgta
     3421 aaaactataa aagaatcaaa aactgtagta tggaatgggc caatgggagt atttgaattt
     3481 gaaaactttg caaatggtac attatcagta gctagagcta tggcagagtt gactgatgca
     3541 actactgtaa ttggcggtgg agatagtgca gcagcagtta atcaattagg atttggtgat
     3601 aagatgactc acgtatcaac aggtggagga gcatcactag aatttttaga aggtaaagaa
     3661 ttaccaggta ttgcagcatt agataataaa taaactaata tatagaggag attgtaaaat
     3721 gagaaaacct ataattgcag gaaactggaa aatgcataaa acaataaaag aagctttaga
     3781 atttgtaaat gaagttaaag ataaagtaaa ttctgataaa gtagaagctg ttatatgtgc
     3841 accatttact ttattaaagg atttaaaaga agctactaag ggtacaaata taaagatagg
     3901 tgctcaaaat atgcactttg aagaaaaagg agcatttaca ggagaagttt cacctcttat
     3961 gttaaaagaa atagatatgg actatgttgt aataggacat tcagaaagaa gacaatactt
     4021 caatgaaact gatgaaactg taaacaagaa agttttaaaa gcattagaag taggaataga
     4081 cccaatatta tgtgttggag aaactttaga acaaagagaa gctggaaaaa ctaaagatgt
     4141 ttgtaaagtt caagttgaaa aagctttaga aaatgttctt aaagatgatt tagcaaaagt
     4201 agttgttgca tatgagccaa tctgggctat tggaactggt aaaactgcaa ctgctgaaga
     4261 tgctaatgac gttatatctt atataagaga agttataaaa ggattatatg gagaattagc
     4321 taatgaagtt agaatacaat atggtggaag tgttaaacct tcaaatgtag ccgaaataat
     4381 gggtcaaagt gatatagatg gagctttagt aggtggagct agtttagcta gtaatgatta
     4441 cctagacctt gttaatttct aaggagtgaa atgatgaaaa aaccagttgc tttaattatt
     4501 atggacgggt ttggatacaa taaggatgtt aagggaaatg caattgctga gtccaaaact
     4561 cctaatttag atagaataaa aaaagagtat ccaaacacat tgataaatgc tagtggtctt
     4621 gatgttggtc tacctgatgg tcaaatggga aattcagaag ttggacacac taacataggt
     4681 gcaggtagaa tagtatatca agatttaact agaataacaa aatctataaa agatggtgac
     4741 ttttttacta ataaagtttt atgtgaagca atggataatg caaaagaaaa ttctcttcat
     4801 gtaatgggac ttttgtctga tggaggagta cattcacata tagaccatct taaggctata
     4861 atcaaaatgg caaaagataa aggcgtacaa aaggtgtatg ttcacgcatt tactgatggt
     4921 agagatactg accctcaaag tgcattagaa tatgccaaag aagtacaagc tagtatggat
     4981 gaaattggag taggtgaatt tgctacagtt tctggtagat actacgctat ggatagagat
     5041 aagagatggg aaagagtaga acttgcatac aatgccatgg ttagaggtat tggtgaaaaa
     5101 gcaaattcta ttgaggaagc tattcaaaac tcttatgatg atggaaaaaa tgatgagttt
     5161 ataatgccaa cagttattat gaaagatgat aaaccagttg gaagtataaa ggaaaatgat
     5221 tcaattatat tctttaactt tagaccagat agagctagac aaataactag agctttagtt
     5281 tgtgaagagt ttgatggatt taaaagagaa gatattaaaa acttctttgt atgcttaaca
     5341 gagtacgata taactataga gaatgtgcat atagcatttg gacctcaatc tttagccaac
     5401 actctaggtg agtatctagc taaaaatgga aaaactcaac ttagagctgc tgaaactgaa
     5461 aagtatgcac atgtaacttt cttcttcaat ggtggagtag aagagccaaa taaaggtgaa
     5521 gaaagactat tgataccttc tccaaaggtt gcaacttatg atttaaaacc agaaatgtca
     5581 gcatatgaat tgacagataa agctttagat aaattaggag aagataagtt tgactttata
     5641 gtattaaact ttgcaaatcc tgatatggta ggtcatacag gaagtataga agcggctata
     5701 aaggctgttg aaactgtaga tacttgtgta ggaaaattga tagataaaat agtagagtta
     5761 ggtggaagtg caataataac tgctgaccac ggaaatgctg aatatatgtt agacccagaa
     5821 acaggaaaaa ctgtaacggc tcactctatt aatccagtac catttattgt agttggtcaa
     5881 gaatatgaaa gtgcaaaatt attggatgga ggaagattat ctgatatagc accgactgtt
     5941 ttagatatga tgaagttaga aaagccagaa gaaatgactg gccattcact tatttcaaaa
     6001 tagtcgattc tgataagtag agaataatat ataaactaca atataaattt aaaaataatg
     6061 cagtttaggt ttattttgta aagtttagac tttatgacag aagatttaga ttttgtaagt
     6121 tttggatatt gtaaggtgta gatgaagata tattttataa aatttacaag atagacaatt
     6181 ta
//
LOCUS       DAEPXW010000159         6157 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.163, whole genome shotgun sequence.
ACCESSION   DAEPXW010000159 DAEPXW010000000
VERSION     DAEPXW010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6157
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.163"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            126..776
                     /locus_tag="KRM55_003488"
     CDS             126..776
                     /locus_tag="KRM55_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBH1595677.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(916..2292)
                     /locus_tag="KRM55_003489"
     CDS             complement(916..2292)
                     /locus_tag="KRM55_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1595678.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2308..4221)
                     /locus_tag="KRM55_003490"
     CDS             complement(2308..4221)
                     /locus_tag="KRM55_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1595679.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4357..4989
                     /locus_tag="KRM55_003491"
     CDS             4357..4989
                     /locus_tag="KRM55_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBH1595680.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5128..5667
                     /locus_tag="KRM55_003492"
     CDS             5128..5667
                     /locus_tag="KRM55_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH1595681.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAARKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(5843..6013)
                     /locus_tag="KRM55_003493"
     CDS             complement(5843..6013)
                     /locus_tag="KRM55_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1595682.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
BASE COUNT         2274 a          861 c          863 g         2159 t
ORIGIN      
        1 tgcgtgagta gaatgaattt gtcaagttta atttaattgt aattgtatct tttattaaaa
       61 ataatataaa ttaaaacata taaataaaat attttataca atatattgta aaggaggtaa
      121 ctttgatgaa agcagaaaaa acaagtatat atccaattat taaaaataat ttaaacaaaa
      181 tatcaattgt tgaatataaa aagggtcaaa gatttgtagc atcagataaa gacttacaag
      241 aagtgttctt tataatagag ggagttgcat tagtggagtg tactactaga ggaggaaata
      301 aatttcttgt tgacattgta cctgaaaatg aatttatagg caaaattagt tacatatatg
      361 aacataattt gaaatgtgat atatttgcaa agaccaatat aaaattattt cgatttgaaa
      421 aaaatgtatt tgaagagttt tatctcaaac cagattttat tgcactattt cacagaaaat
      481 gtacaagaag aatatatgaa ttatataaaa ccagaatggt aagagaacta ttttcttgca
      541 cagaagttat tgcctattgt atatcaaata aacaagaaaa taatgtctgc aatataaaag
      601 ctattcgtaa tttcagtgaa atctattcaa ttagtagaaa aagtagatac cattctctgc
      661 taaagttaac tgaaaaggag atagtaaaaa aaatgggtaa tacatatgaa attttaaact
      721 atgatgaatt acataaattg gcatttgaag taaaagagtt tttggaagat gagtaaaaat
      781 tgttacttaa tcaaaataaa gtataataat ttctgtaaaa aatagaaata gtctcactga
      841 aaatcaaaaa tactttagtt attttcaatg agactgttta gaaatattgt atacttataa
      901 tgtatagtat aattattaat caatttcctt tactatatta atagcccatt ttttagataa
      961 tgctctagga acaccaaata taaacttaac cacttcttca ctataagtga gcaaaacgag
     1021 tacaaatata ggtgcacctt taaatgcagc tataaaagtt agaggaatag aagctaacca
     1081 catacatcct aattctagaa atagagcata tttagtatct cccccacttc ttaaaatacc
     1141 aattataacc aatgtattaa aagatttaag agccattagt attcccatta taaagaatat
     1201 cttagttata tcagaagcta agctatcaga aacactaaac atttttaata ataatggtat
     1261 atttaaaatt aaaataattc caagtattaa accagctgaa aatacaagta tagaaaactt
     1321 tttagcatat tcaatggctc ttttaatatg gtcagctcca agttcatttc caagcataat
     1381 agatgcacca gatgcaatac atacagctgt cattatgaag aaattacctg tactggttgc
     1441 tatctggcta gctgctatag cagaagtacc agctcttgca tatgcaacag aatacaggac
     1501 agttccaatt gcccatacag agtcatttac aaatatagga aagctttttg atgaaaaaga
     1561 ttttataaaa attttatcaa tagcttttag attttttaga ccaaacttta atatatagtc
     1621 ttttttataa aggtaaacat aagtaatcat taaaattaat tcacatattc tagcaataac
     1681 agtagctaga gcagcacctt ttacacccaa tgcaggaaga ccgaagttac caaatataaa
     1741 tccataattt aaaataacat ttgttacaag tgcaaatgca ctacaaatca tacctaactt
     1801 aggatttcta acacctcttg aaccagtact aaatacagta cttacagcaa ttaatggata
     1861 actaaatact gcaatactaa agtaatctat acaaagtttt accacctcag aatcatacga
     1921 aaatatgtgt ataattggct ttggtgttag taaagcagga ataacaaata caaaacttaa
     1981 aacaattgcc aatacacaag taagacctgt gacttttctt atattactca catccttctt
     2041 tccataaaac tgtgaaataa aaactccagc acctcctgtg ataccagata aggacatatt
     2101 aaaaagaaag aaaaattggt ttgcaactcc aactgaagct acagatgttt cccccaaact
     2161 acttatcata attgtatcta ttacatttac agaagtagaa attaagttct gtatgataat
     2221 aggtatacat aaagatagaa gtattttata aaatctttta ttttcgtctt ttaaagaaaa
     2281 tagttcttgc aaataatcct ctccttttta cataaattct tcccactcat catatagaga
     2341 ggcaaggtta ttttctaaat taattttttc ttggctaact tctttagctt tatctggatt
     2401 agagtatact tcttcttgac ataaaagtat atctaatttt tcaatttcaa tctctaactt
     2461 ttcaatttct ttttctatat tttgtctttt tattctattt ttcttttcta tttctctttg
     2521 ttctctctct tttctttttt catcttttat ttgagttcta gttttttctt ctttttcttc
     2581 tataatactc atctcttgga tttgcctttt tttatctata taataatcat aatttcccag
     2641 atattcagta attccatttt catctaaaac taaaatttta tcaacaacag tatttagaaa
     2701 gtatctatca tgtgatattg taaatatagt cccatcataa ttagttaatg cctcttcaag
     2761 gacttcctta gaatcaatat ctaggtgatt agtaggctca tctaataaca ataagtttgc
     2821 atttgatagt ataagtttaa gtatggcaac tctagctctt tctccaccac tcaatgtaga
     2881 aatcttctta aaaacttctt catctacaaa taaaaatgcc cctaacatat ttctcaaagt
     2941 agtttgagta agatgagtat tattttccca aatctcatca attattgtgt tatctaaatt
     3001 aagagttttt tgttcctgat ggaagtagga aacatgtaca ttagttccaa atttaatatt
     3061 gccactaaga ggttgtagtt cattagttat tattttaaat aatgtagatt tgccaacacc
     3121 atttgcacct ataagtgcaa ctttttcccc tctatatata tctaaatcca agtctttaaa
     3181 aagtattctt tctccataac ccatagatac atctctaatt tgaagaacat cattaccact
     3241 ctgtacagaa ggcgtaaatt gtatacgagc ttttttccta taagcttctg gtttatctaa
     3301 aacgtctacc ttgtctaatg ctttttcttt acttcttgca cgctttaggt gtttttctct
     3361 accataagct tttagtcttt caattgattc ttcttgcttt tttatttctt tttgttggtc
     3421 ttcaaatttc ttaagctcta gttctttttc tattttagat aactcaacaa atttagagta
     3481 gttaccatta tatactttaa gttttttgtt gtgaacttca aaaattctat ttacggattg
     3541 gtctaagaaa tatctatcat gagatattaa catgacagtc cctttatatt gttttaaaaa
     3601 tacttctaac cattctattg cttcagagtc taagtggtta gtaggttcat caagtaacaa
     3661 tagagttggt ttcttaagaa gtaattttcc taaaagaact ctagtttttt caccaccaga
     3721 aagtatgctt attggcttat ccatatcatt gtcactaaat cctaatccct ttagaactcc
     3781 tttggcttca gatttatatc catatccatt taaatctgaa aataattcta gtttatgtga
     3841 atattcatcc atgatttttt ctataattgg agagtttgtt tttgtacttt cttcagatat
     3901 tttaacctcc aattctctta aataggattc catttctatc aaatttttaa aaacttctag
     3961 tacttcttcc aaaatagtat tatccgaata aaaattggta ttttgttcta aatatccgat
     4021 ttcacaatct ttagaagtgt aaatatctcc actatcatat ccataaattc ctgaaattat
     4081 tttaaataaa gtagtttttc cagtaccatt aacaccgatt ataccaattt tatcgccttc
     4141 atttactgta aaactaatat tttctaatat agaatctata ccaaaacttt tatttaagtt
     4201 attacatgac aaaacaatca taaatttcta cctccttgaa ctatctaaaa ttataatgtt
     4261 ttgatataat ataatcaagg ttatatgtat tagttttgaa aaagaaatat tttattgtga
     4321 atcaaacaaa aaagaggaca cttttaggag gtgaagatgt tgggaaataa aaatatatca
     4381 atggcagtta taagaaggct cccaaaatat catagatatc ttggagactt attagatagg
     4441 gatatacaaa gaatatcttc taaagaattg agtgatataa tagggtttac cgcttctcaa
     4501 ataagacaag atttaaacaa ctttggtgga tttggacaac aaggatatgg ttataatgta
     4561 gaagctcttc atactgagat aggtaaaatt cttgggttgg atcgaccata caacgcagtt
     4621 cttgtaggag caggtaactt aggacaagct atagccaatt atgcaggatt tagaaaagct
     4681 ggattcgaga taaaagcttt atttgatgca aatcctagaa tgataggttt aaagataaga
     4741 gagtttgaag tattagattc agatacttta gaagacttta taaaaaacaa taatatagat
     4801 attgctgtat tatgtatacc taaaaatgga gcacaagaag ttattaatag agttgtaaaa
     4861 gctggaatca aaggtgtatg gaattttgca cctttagatt tagaagttcc gaaaggtgtt
     4921 atagttgaaa atgtaaactt aacagaaagt ttatttacct tatcgtattt aatgaaagaa
     4981 ggaaagtaga caacttaaac atattaataa tgggcagttg tgaagagtat tgagaaagtc
     5041 agaagattta atattaaatc ctctggcttt ttgaaatatt aggataaaaa tttaaataat
     5101 gtatggaaat aaacaatatt aaggagagtg gtttttgtgg aggaattatg gaaaaaggca
     5161 attgaatttc atggtcatga atgtccagga ttagctatag gatttaaagc agcacttgca
     5221 gcaagaaaat atttaggatg taaacagtca ggagatgagg aaattgtatg tatttctgaa
     5281 aatgatgctt gtggaataga tggtatacaa gtcgtgctaa gttgcacaat gggtaaagga
     5341 aatttactac ttaggatgac tgggaaatca gtatatcatt tctttaatag ggaaaatgga
     5401 aaatctataa gaatatatgt aaagtcaaag ccatttcaaa tggatagaga aggatataaa
     5461 aagtacttat tagaaagtga ttttgaagaa atatttgaga ttacagatac taagttaaga
     5521 cttcctgaaa aagcaagaat atttaaatct cttaaatgtg aagtgtgtgg tgaatttgca
     5581 tctgagcaat atataaggat tgaagaagga aagaaagtat gtcttgattg ctttaataaa
     5641 tatgaaagat tttatgagga gtattaaaat tataaattag attaaagtta aaagtattag
     5701 atatatgcta acagtatttt aagatgaatt aggtagcaac ataataaaat atataaataa
     5761 tattacttga atcatacata attaaaaaga ggctgattag tatttagaaa ataaaatcag
     5821 tctctttatg aataacgaat tattattctg gttgaggtgc atctacagga caagctcctg
     5881 cacaagaacc acagtctata caagaaccag catctataac atatgcgtcg tctccagctg
     5941 atatacagct aacagggcat tcagcctcac aagcaccaca gcttatacaa gcgtcagtaa
     6001 ttttatatgc cattttgaaa tcctcccttt tatatgtatt gtaattcaat aacattataa
     6061 caaatattat tgaatataac aattaaatta attctacaac aaaaacttta ttatgatatt
     6121 cttgttttaa agttttacaa taaagtttaa tctgctt
//
LOCUS       DAEPXW010000160         5966 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.164, whole genome shotgun sequence.
ACCESSION   DAEPXW010000160 DAEPXW010000000
VERSION     DAEPXW010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.164"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(43..705)
                     /locus_tag="KRM55_003494"
                     /pseudo
     CDS             complement(43..705)
                     /locus_tag="KRM55_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(865..1401)
                     /locus_tag="KRM55_003495"
     CDS             complement(865..1401)
                     /locus_tag="KRM55_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH1595683.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEETKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(1474..1887)
                     /locus_tag="KRM55_003496"
     CDS             complement(1474..1887)
                     /locus_tag="KRM55_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1595684.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2353..2886
                     /locus_tag="KRM55_003497"
     CDS             2353..2886
                     /locus_tag="KRM55_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBH1595685.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEGTI
                     SDMQSNINGIEGTISSMQGSISSMDGTINSMQDSITDMQVEIKEVNSRLDNMEPDIKD
                     LKTGQVETSSRLDTIQSDVTEIKSDVKINRNTLDTVIKHTSSLVKDTSDIKNDLNNIE
                     IVTSKNSNDIAKLKSVK"
     gene            complement(3536..3673)
                     /locus_tag="KRM55_003498"
     CDS             complement(3536..3673)
                     /locus_tag="KRM55_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1595686.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDKSYDIVFSCIVFH
                     H"
     gene            complement(3899..4432)
                     /locus_tag="KRM55_003499"
     CDS             complement(3899..4432)
                     /locus_tag="KRM55_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH1595687.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            4749..5099
                     /locus_tag="KRM55_003500"
                     /pseudo
     CDS             4749..5099
                     /locus_tag="KRM55_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2152 a         1008 c          702 g         2104 t
ORIGIN      
        1 taactcatga ctaaagtcac aagtgttcgt agctattttt taatcaaact ggaatacaga
       61 ctccattcct aggaaattgg ctgaaatata gtctgctgtc aaagatgctg tcatcacaga
      121 aattaaaaca gatactgaaa agtttttatg gacttcttca agtgaaaaca taacacccgc
      181 cagtggtgca tgaaaggctg ctgataatcc agcacttgcc ccacaggtta acaggaattt
      241 ttcctctgtc ttccctcggt caagagctct agaaatacct ttacctgcca tagcaccaag
      301 ctgaatggaa ggaccttccc ttcccaaagc aagaccaccc atgagtgata agaatcctcc
      361 aataaatttt gttggcaaca ctcgccacca tacttgtttt attttccctg tcatttcccc
      421 ctcaagctga gggataccac ttccagaaat cattggctcc cagtccacca actttgatac
      481 aatccacgca agtactgcaa gtactgcaaa ccaagctatt atttttattg tagaaccttc
      541 tacaaatttt aaaatttggc taagccaagt accagcctgc cctaaaagta tcctgtataa
      601 aagcacaatc aaaccagcca cagccccaac cataagtcct tcaccaatca aaattacctg
      661 aaagtgctct gcccgtttga taatatgaga tgtatccttt ttcatactgt tcctccttca
      721 tccaataatt ctacacaatc tgaatctcca atgactaaag tcatgagtgt gtacagatat
      781 tttttaatca acaaaaatag atttttactt actaaatata agaaaataat tgctcaattt
      841 ctcaataaat gtaaatttat tcttttaggt atttattctc cacagtcgtg cttcttccag
      901 caaaatattt attagttctt gctttctctg tgtatagatt ttacgattgt cctcaaactg
      961 taatgctaat ttttgtttat gactatcata gagttttgct ttgtctgtaa aagtatttag
     1021 ataatctcga aaattgatat aattattcca tgcaacacta ttccattcaa caacatgaat
     1081 atggtgagta cgagtatttt tctcaaaatc tcccatagca aaaagtaatt gttttggtac
     1141 atcctgacct cgaaaaacga ttccacattg ctctaacctt tcgaggtata atttagtttc
     1201 ctctaaagaa gcaacaccta caacaatatc aataataggc tttgcgctaa tactgggaat
     1261 agaagtgctt ccaatgtgtt gaatatcaat agcagtctta tcccatatac ttttcaataa
     1321 tataatgaca tcttttgcac ttttatccca tatcatctga tgttccaata atttaaccat
     1381 accacatttt aaacctatca ctatatacca cctcaatata atccacctat atatatatta
     1441 caattttttc tatcttgata aacagtgatt tagctatttc actttttctt gacactcgct
     1501 acattcccta tcatgaatag atataattcc tccacattta gaacaagtat atctctcctt
     1561 ctgcttttgc ataaacttct ctaaaccgta ctgctgaaca aatttactat tttccataag
     1621 gcttgcttga tatctcttgt tataactttt ttcaagattt tttatgagtt tacaaggaaa
     1681 attgaaacat tcaaaacaat aaaacaaccc tttttgacag acacaatcct ttattttaca
     1741 cttacggcag tgttctggct ttcctgtatc gccgttcaaa caaccagcac atggcttttt
     1801 gtgataacaa tgcttatagc aaaccataca attcattcca caaggagcaa acataatcgt
     1861 atcaatactc tcttttggca ttttcataac attttactcc tttcaaaaat ccaatttgtc
     1921 gaattgttat atattcatat tgtaacataa aaaatagcta aaaaattcat gcactttcat
     1981 tgccaataaa ttttcaagga aatatgaagg tttaaaacta agaataaaaa gagataaaaa
     2041 ggaagctact aataaaaata ttcaaataca agtaatcaat ataaataact taaggtatat
     2101 ttaaaagtat atgatattac cagcagtttt aaatacaaat ataaccacac atgcctcaaa
     2161 aacacttatt acagtatctt agaaacttag acaatacata agattcatta ataaaaaagt
     2221 tctcaatata gatatattta accatgtttt gaatagcaga taattatatg attaaaaatt
     2281 aaatatgaca tagcgtttgt ggaatataac acctaaatta tgttataata ataaaacagg
     2341 agtgtgatag tgatggatga aaaaatatta gagttattac aggaaatgca aggtaatatt
     2401 agtaatatgc aaggtagtat cagtggtatc gaaggcacta ttagcgatat gcaaagcaat
     2461 atcaatggta tcgaaggcac tattagcgat atgcaaagca atatcaatgg tatcgaaggc
     2521 actattagta gtatgcaagg cagtatcagt agtatggatg gcactattaa tagtatgcaa
     2581 gacagtatta ctgatatgca agttgaaatt aaagaagtca atagtaggtt agacaatatg
     2641 gaacctgata ttaaagactt aaaaactgga caagttgaaa ctagtagtag acttgatact
     2701 attcagagtg atgttacaga aattaagtca gatgtaaaaa ttaacagaaa tacattagat
     2761 acagtgatta aacatacctc ttcattagta aaagatacat cagatattaa aaatgattta
     2821 aataatatag agatagtcac atctaagaat tcgaatgata ttgctaaatt aaaatcagtt
     2881 aaataatata ctatagtaaa aaatacctga aaatttcaca tacttcttta aagttatacc
     2941 aaattttata cagaaatact gattatccga caacacactt tacttataaa taatttatta
     3001 aaaaaatact cattttatcc taaaattaac acgactaaat gagtcttgat ataataataa
     3061 aaaataaggg agattggaca ctaaaaagtt gtgtatctcc cttatattct ataatatagt
     3121 tatataattt ttcagcctaa aataaaagtc catctttgat taaaacacat ccccttatca
     3181 cttataaaag gataaaatct tattttcatt tttccattta tatcttcttg cttaagagta
     3241 ataatttttt cttttgatac tttaagtgtt tggttaaatt taaccaatcg actaagtttt
     3301 gttcaacatc tatttttcat attttccaat acttaatcta ttttttataa ataattcttt
     3361 catttctaac ttacttacat tttttacata aaacgaaaca tataaatttc aaccttatct
     3421 tgtatggttc ttaatactta ataagtagct taagtatcaa tcattataaa tttttccctt
     3481 acatttaaca ctcttaccat ttccaaaata tacaaaatat attttgaaca cttgttcaat
     3541 gatgaaatac aatacatgaa aatacaatat cataactctt gtctaaaaat agaagttctt
     3601 caacataacc tttcacaaaa aacatattat ctaagtattt tttgtctgct ccttgttttc
     3661 ctgtttgtag catataaatt actgcatcta aacatataac tactcacacg aaaaaagaaa
     3721 ataaacttcc aaaatacaag ctctaaaaac tacctctaaa gttgtataat gtttactagg
     3781 aataaggttg tataacatat agtttaaata atcatttttt aaaattgcaa gttattgctt
     3841 tcaaaattag atgtttgtat atcaaataaa tgattaagaa tttctaaatt taatggcttt
     3901 ataatgcgct ccctttcttt gggataaaat aatgttgcac agatactttt tctaaagata
     3961 acaattttat ttttctatca attccaccag catacccagt caaactccca tttgttccta
     4021 caacacgatg acatggaata ataatagaga ttccattatg ccctactgca ccaccgattg
     4081 cttgtgctga cattttagat attccttttt gttgagcaac tttatatgca atttctccat
     4141 aagtgattgt tttaccatat ggtatttgtt gtaaaatttt ccacactgta gtctgaaaag
     4201 gagtacctac catatggagt gatggtgtaa aattgggttc ttttcccgaa aaataaatat
     4261 ctaaccattt ctttgtctgc tcgaaaattg gcaattcttt ttcttgatgt tcttggtcaa
     4321 gattataagc ataatacttt tgattctcaa accaaagacc agttaaccca atattatctg
     4381 atgctaaaag aatatttcca attggactat ggtaatagct aatatattgc atacaattcc
     4441 tccttatatt ctgaaaactt cactcaaatc attagacact tcttttctat ctaccattat
     4501 gtaaaaacat actaatataa tttccttcta actacacttt cgttataata tctatcctca
     4561 tatcatatta gttttatatt tacctgcatc tgttcatcct tttttccctt tccctttgat
     4621 gaatataaaa ttcatacatt taagcttcct actgtattaa cttttataga agtgtatatt
     4681 ataattttat cactaaatag gccaaaaaaa tatcgatata gcatcaagta atatcataat
     4741 actttcaaat gggaaaagta agaataggct gtaaaaaaga aaagtatttt tatgttagaa
     4801 atccagtaaa atcattagta gatagaataa cagaaaacga acaatttgct atttatcatt
     4861 ttacacataa atataattga cgcaataaag tgttttctat tctacaacga ttaataaggt
     4921 tagaaaaaag taaaaatgaa ctgtatatgt atgaagcatt agtttctgtt tctttccttt
     4981 ggcttattat gataaaaaat attgttttgc taccaataaa acacaaaaat ataattaata
     5041 tccatatgca aaaaatttta cgttatattg aaaaatacta ttgttttaca ttatattgaa
     5101 gggtactatt gtgaaaactt aattttggag tactatcaag cagtggtaat atcaataaat
     5161 cagagtgctc cagatgattt gaactaagtt taaatactat accttataaa tattttactg
     5221 agttttgttt attaaaagca actcaatttc taaaaggcac aaatgagcta ataagtgaca
     5281 ttgctataaa agttgttttt catcaaataa tctattttag taaatgtttt aaagaaaaaa
     5341 cgggatattc tccaaaagtg tacagaaata taaaaaaaga gatatgattt tttatttctt
     5401 ttgattatcc aaagagtaaa taaaaaatat tgtaaaaaac ttactaacaa cggcaatgct
     5461 ttgaactatg gtaatacttt gaacttttga ttggactttt tttgctaaaa taatatattt
     5521 aaatagcaaa gtaatctgtt taatcaataa aaaataagag ataaaagaaa tcaactaaaa
     5581 cttttacctc ttattttgat agtttatcag agctaatatt tacactcttt ttatttttga
     5641 tacttcatta aaaatgatgc ttactctcca ttcactttta attcttcatt aaaaatgatg
     5701 cttattctcc attcactttt aattcttcat taaaaatgat gcttactctc cattcacttt
     5761 taattcttca ttaaaaatga tgcttattct ccattcactt ttaattcttc attaaaaatg
     5821 atgcttactc tccattcgct tttaattctt cattagaact atgcttactc tccattcact
     5881 tttaattctt cattaaaaat gatgcttact ctccattcac ttttgattct tcattaaaaa
     5941 tgatgcttat tctcttttca ctttta
//
LOCUS       DAEPXW010000161         5929 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.165, whole genome shotgun sequence.
ACCESSION   DAEPXW010000161 DAEPXW010000000
VERSION     DAEPXW010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5929
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.165"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            35..1342
                     /locus_tag="KRM55_003501"
     CDS             35..1342
                     /locus_tag="KRM55_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595688.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEVFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1428..1690
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1816..2619
                     /locus_tag="KRM55_003502"
     CDS             1816..2619
                     /locus_tag="KRM55_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1595689.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            2657..3268
                     /locus_tag="KRM55_003503"
     CDS             2657..3268
                     /locus_tag="KRM55_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH1595690.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSSITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3300..3971
                     /locus_tag="KRM55_003504"
     CDS             3300..3971
                     /locus_tag="KRM55_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH1595691.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4270..4632
                     /locus_tag="KRM55_003505"
     CDS             4270..4632
                     /locus_tag="KRM55_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBH1595692.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            5068..5769
                     /locus_tag="KRM55_003506"
     CDS             5068..5769
                     /locus_tag="KRM55_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBH1595693.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
BASE COUNT         2374 a          541 c         1037 g         1977 t
ORIGIN      
        1 tgagttttac ataaaagcaa aggtgggaat aaaaatgaaa gaaattgctg atgctataac
       61 atcagagtat ttaagctatg gtatcaatga agatattagt atctatgaag gtagattttg
      121 catatattta gataaaaaat atagatgtaa tgggaaaatt tattataaaa tgacacctcc
      181 aatatctata agttttaaag cagacatagg ttgtgttgaa gagatagaca atgaagatga
      241 caatttagct ttagattatg ataatgctat tcttgaagtt catggatata aaattatttc
      301 tataacaata aatactttaa gtgaatttag tgtagaaggt tatatcaatg atgactgcat
      361 aaaatctaag aactcctatg ttgaatatgt agattttaat ataataaact tagataaaat
      421 acctggaaaa ctcattaaat acaatgataa ggtatacgca ggtagaattg aatttgatat
      481 aaatgattat gttgtaacta tagacaagcg atatgattat agaaaagaat taaaatcaga
      541 attaaagtct aaatctggag caataataac tcatataggc aggattagaa gaaaagatgg
      601 tagaattttt agaacaaata atacaataaa tcttttagat aggatatcaa cagctttgag
      661 ttttatgtgt ggaagatatg tagggttttg tttggccaaa gggtatagaa gtggtaatga
      721 agtttataga atatggaatg aaaatcaaat atctcctttt agatatgtac caacatggtc
      781 agatacactt tcaaattatc ataatatgga aaaatatata agccttatgt gtaaaaagct
      841 agaagatttt tattatggtt ctgctataaa gagtgttgtt gattggtaca tagaatctct
      901 tggaagtgct accatggaaa acaatataat atctgtacaa attgcacttg aaactttgtc
      961 atatgtaatt ctagtggaac aaaataagat acttacagat gaagtatttg actgtaattt
     1021 ggcatctaaa aatataagac tcttacttga tacatgtaag ataccatatg gtaaacatga
     1081 attaaatata tttgataata taataaaaaa taaatttgat gatggagtgg atttagttat
     1141 ttatttaaga aatagcatag ttcatccaag tagaaagact catagagctg tgttagaggt
     1201 tgaagatatt tggaatataa tttcaatagg aacgagatat attgaacttg ttttactctt
     1261 tattttaggt tatagaggag aatattcaaa cagattagta gaaagatgtt atggtgaagt
     1321 ggaagttgta ccttggaact agatttttat atttatttta aaatatatat tgacatatat
     1381 tgccttatgc tataaaatca atatcataat aataattcag aataacatta aatgctaaga
     1441 aaagaaatag taaaagtagt taatcttaaa cagagagttt ccgattggtg agaggagcaa
     1501 tagattttac tttgaacaca tctttgagca ggactctgaa agagtagaaa tactttatta
     1561 ggagatttcc ggaatccttg cacccgttat agtgctagag tataataatt ttattgtact
     1621 taaagaggtt agtgtcgtga ggcattaatg aacagaggtg gaaccacgag agttaactcc
     1681 cgtcctctag cagaagctag aggcgggagt tttttaatat aattttttaa gcgcgcagag
     1741 aattatattg caatagatac actttttaaa aaataatcaa aatattttaa aaattaaaag
     1801 acgagggaga atattatgaa aaatatatta aaaaaagtag gaatatttac aattatgtta
     1861 ggtttattag gtggagttgt aggttgttca aaaccagata atgaaaaaga taaggatgct
     1921 tcaaaggaat ctaaaaaaga agtagttgta gggtttgata atacgtttgt accaatggga
     1981 tttttagatg aaaagggaga tacagtagga tttgacgtag acttagctaa agaaacattt
     2041 aaaagacttg gaatggaagt taagtttcag cctatagatt ggtcaatgaa agaaactgaa
     2101 ttaaatgatt caaaaactgt agatgtatta tggaatggat attctataac agacgaaaga
     2161 aagaaaatag tatcatatac agaaccatat ttacaaaata agcagataat agttactcta
     2221 agtgactcaa aaataaattc aaaagctgat ttaaaagata aagaagttgg aacacaacaa
     2281 ggttcaacag cacttgatgc agtggaaaag gataaagatt ttatgaatag cttaaaaggt
     2341 ggagcaccag ttctttatga tacttatgat aaagcactta gagatttaga gataggtaga
     2401 actagtgcag ttgttggtga tgaagtttta attagatact atatgggaca aaagggtgaa
     2461 gacaaataca aggtattaaa agacgatttt ggattagaag attatgttgt agcaacttct
     2521 aaagaaaatc cagaactttg tgagaaaata aatgaaacat taaaagaaat gaaaaaagat
     2581 ggaacttttg acaagattta tgataagtgg tttaaataga agataagtta gctgttaaga
     2641 agggggcact aaaggcatgt tacaaggttt agagatagtt atagcaatgt tttgtataac
     2701 attgatagta tcaattccat tggggattgg agttgcattt ttaagattat caaagaataa
     2761 attagtaagt agtattacac aatgttatat attgataatg agaggtacac ctttactttt
     2821 gcaaatgata gtcatatttt acggattacc tcttttagga attgtatttg acagatttac
     2881 agctggagta gtagctttct tcttaaatta tgcagcatat tttgcagaaa tatttagagg
     2941 tggaatacag tcaatcgata gaggacaata tgaagcttca aaagtactag gatttgataa
     3001 gtttactatg tataagagag taatctttcc acaagttttt aaaagaatac tagcacctat
     3061 ttcaaatgaa gtaatcacat tagtaaaaga tacatcttta gtatatatat taggattaaa
     3121 tgatatttta agaatatctc aaatagcaat gaacagggaa gcaagtctgt taccattatt
     3181 tgaggcagga gcgatatatc ttatatttgt agctatactt actaagggat ttgaattact
     3241 tgaaaaaaaa tattcttatt atagataaag ttacaatatt ataggaggag gttttttata
     3301 tgttgaaaat caaaaactta aataaatcat ttaaaaaaaa tagagtactt aaagatattt
     3361 cttttgagtt agaagaaggt cagattggag ttttacttgg taagtctggt gcaggaaaga
     3421 ccacaatatt aaggtgtata aatggtcttg aagaatttga tagtggagag attataatag
     3481 ataatgaggt aataaaaaat aagagagata tggcaaaaat acgaggaaaa ataggtatgg
     3541 tttttcaaaa tttcaactta tttcctcata tgacagtcct tgaaaatata attgaatccc
     3601 cagttaatgt ttttaaagtt cctagaaaag aggctgaaga gagggctaga gaacttttaa
     3661 gattagttga tttagaagat aaattaaatt cttatccatt tgaattgtca ggaggacagc
     3721 aacagagagt tgctatagct aggtcatgtg cattgatgcc aaaagtcctt tgttttgatg
     3781 aacctacttc tgcacttgat attgatacta ttcaaagagt agtcaatata atgaacagac
     3841 ttaaagacaa aggtatgaca atattaataa ttacacatga tgttgtcttc tcaaataatg
     3901 ttgcagataa aattataagt ataaaagatg gtatagtaga aaatgttcaa ataaaagaaa
     3961 aaattgttta gagttttata aatataaact agggtagaat tttataatat aaataaaggg
     4021 caagtaaaat caaatatact atgccctttt gttatctcaa aatttaatct tatattttat
     4081 gtttaagtta cattataatt tataataaaa ataaaaggac tatttaaata tataatgtga
     4141 ataaatgttt aataatttga aatatgataa ttttttatgt tgaaagctta taatgattat
     4201 gatataaatt ggttatagta tacaatttat gggtataaca ataaaaaatt agaaaggaat
     4261 ttttataaaa tgattaaatt atatggatat acaaaatgct ctactgttaa aaaagctaaa
     4321 aattggctta aggaaaataa tttagaattt gaagatatag atatggttca aaaccctcct
     4381 agtaaagagg agttaaaatc aatttataag actagtggat atgatataaa gaaatttttt
     4441 aatacaagtg gtatgaaata tagagaattg ggtcttaaag atattgtaaa aactgaatct
     4501 gatgataaac ttttagaaat attggtaagt gatggtatgc ttattaaaag accattactt
     4561 ttggatggta aaaatgtatt attgggcttt aaagaagatg tatggaaaag tactttgcta
     4621 aaagaagatt aggaagagat aggtgtgttg attaaaatta ttaattaata cacctataaa
     4681 tttatgtatt aaatctaatt tttataaata ttaattagca aattcaaatc aaaaaaattc
     4741 atatcaacaa acatattact tcttattaca aattatatca tatgttttat attaaaatat
     4801 tataatatta caacgaattg ttacaaaatt acttattatt aaccatgaac atttgttttg
     4861 tgctatcata tttatataag ggaattgtca taaaaaatat cttgttcata cagttttata
     4921 tagaaaaaag aaatgaatct tttctttata taagtatatt ttgtaaattg cctctatatt
     4981 tatagtttaa ataatagtgg tattaaaaat ctgacaacaa aaataaaact ttcaaaaaat
     5041 taaatctaaa aagaatagga gataaatatg agtattgaag atttatatga ttttgaatgt
     5101 gttcctttga acaatgagat tgatattgat gttttatttg aaaagatgat agaagatgga
     5161 aaagaaaaag aatatacacc aattatagtc attgatgaaa aagtagggct attaagaaaa
     5221 aatatagata tgattactaa agagtatggt tctcttgaaa actatagaga gtattgttta
     5281 acaaaatata atgaaattga tgtaaatcaa ttttttgatt ttaggaagag tgagatttca
     5341 gaattattaa aggagctaat tgatttagaa gatgattttt atgattataa acattttaga
     5401 ccaattatga atatagatat atttcatgaa tataacaaag tttacatagc taaaattcca
     5461 acaattaaac catatgaagt atttgcatac atacctattg gcggatttaa tgattgtcct
     5521 agagatgaag aacatatagc tattgcaaaa tattggtatg aaaagcatgg aatctttcca
     5581 atcgcaattg gatgtgatac agttcaatat tctgtaaaaa atttaactaa agatggtaaa
     5641 aaatttgatg acttatgtat tgaattagta ttttattgtg aggatattat tatacaaggg
     5701 tatgaaacct taaaggctct taaggatgta ttaaaacgct ctacaatagt gcttttttgg
     5761 tgggattgat attctatcat ttagatagta ttaaattgtt agtcaccaag aatccacttg
     5821 ctttagttat ggggagtgtg tcaaactagg tttttataca cagtgtagca tagtaatatg
     5881 tttaaattac aaaggttaaa aaaatacttt aatattttta atattataa
//
LOCUS       DAEPXW010000162         5871 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.166, whole genome shotgun sequence.
ACCESSION   DAEPXW010000162 DAEPXW010000000
VERSION     DAEPXW010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5871
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.166"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            230..349
                     /locus_tag="KRM55_003507"
                     /pseudo
     CDS             230..349
                     /locus_tag="KRM55_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            476..1378
                     /locus_tag="KRM55_003508"
     CDS             476..1378
                     /locus_tag="KRM55_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH1595694.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGIVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            1990..3003
                     /locus_tag="KRM55_003509"
     CDS             1990..3003
                     /locus_tag="KRM55_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1595695.1"
                     /translation="MGSSFLNDIFRTILVSCIFIVILLVFRITLFKIFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            3355..3924
                     /locus_tag="KRM55_003510"
     CDS             3355..3924
                     /locus_tag="KRM55_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH1595696.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(4260..5597)
                     /locus_tag="KRM55_003511"
     CDS             complement(4260..5597)
                     /locus_tag="KRM55_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1595697.1"
                     /translation="MGIYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
BASE COUNT         2199 a          585 c          967 g         2120 t
ORIGIN      
        1 ttggtagtgg aagtgggtag accttaacgg ataatgccga aggataagat atagtctgtg
       61 cttgcatgaa agtgtaagaa gttcataaga gaactgcata ggtagtagcg aacttatgtg
      121 aacgacaacc tcaaaaatga taaaagttaa gacttacggt tcttaaatat gttatttaaa
      181 attaaatata aaaccttcta aataattgtt ttaaataatt acatttgtta acattattat
      241 aagagaatgg atttgtccta gttgtaatga aactcacgat agagatataa atgcaagtat
      301 aaatatatta aaagaaggat taagactaat aacaattcaa aataaataac ttatgtaaga
      361 accgtaggaa ctacggggat agcctgtgga gaattagtaa gacatatttt agtatgcaaa
      421 attctatgaa gcaggaaccc tgtgacttta gtcatgggag gttcagattg gaaatgtgtt
      481 gccacaagat tattatggat taatagtgat tttaggtgtt attcttggag ttatgggggc
      541 attttacaac tggtttactc tatatgtgca gtctttatac aagaagattc ctaaaattgg
      601 tacctttgga aaactgttga ttccatttat aatggctggt attcttggga ttgttatgcc
      661 tgatgttctg gggagtggac acaatttagt tgaagaactt acaagtcatg aatatatttt
      721 tggaatggtt gttttgattt ttgttatacg ttttatattt tcggctgtta gttttgggtc
      781 aggtgcacca gggggaatat tttttccatt gcttgtttta ggagcattta taggtggaat
      841 atttggtatg gtaggtgtta aagtttttgg aatgaatccc gattatgtaa ataactttgt
      901 gcttttggct atggcaggat attttacagc tattgtgcgt gcccctttga ctggtatcat
      961 attaattttt gaaatgacag gttctgttag tcaaatgctt tcactatcag taatttcaat
     1021 tgtggcatat attgtggcta cacttatgaa gtctaaacct atttatgaaa gtcttcttga
     1081 gaggttactt gaaaaaaatg gagaacctgt acataaagag aggggcgaaa agatactaga
     1141 ccagttctct gttatgtttg gctctcctgt tgcgaacaag gcaattcagg atgtacagtg
     1201 gcctgaaaat tgtcttttgg tagcaattca aagaggtgga gaagaaatta ttcctagagg
     1261 taagacaatt cttagaccaa gtgatgtaat tgtgactatg acagatgaga gagatagtgg
     1321 tgctgtgtat gataaaatgg aaaatttgtg taaagaacat acggcacata ttttttaggg
     1381 ataatgatga atgtttaata atgatagaat atttaatgaa gatttgatta aaaaattggt
     1441 aatttgaaag agagttaagg aattaatata agaaaatgaa aacgtgatat cttagatgta
     1501 aaagagtttg aagaaaataa ttgtatatat ttgttaatga gattatatgg actaatggta
     1561 tatttatact gtgctaaaag ttgcactatt gtatgaggaa tgggaataaa gggtttgaaa
     1621 aaataggtag aagatttttc agatattctt attgggatat tttaattaat atattttaat
     1681 tgcgatattt tgggaagaat agaatttatt tataaatgaa aataattaaa aggggttaag
     1741 gttgtattag ccccttttgc ttatagagtt tggaaatggt atcttgatag tagttgtttt
     1801 atgcttatta tattttatta catattttaa aattgacctt attactccta aatcattgtt
     1861 ctatcaactt ttaaaacact ttcaagacaa ttgcctattg aaaacaaagt taattaaaaa
     1921 cctacatatc agtttagtat tcgtgtagat gattatataa atataaaagt ataagaaagg
     1981 tgagtatctg tgggtagttc atttttaaat gatatcttta gaacaatttt agtaagttgt
     2041 atttttatag ttattttatt agtctttaga ataactttat ttaagatttt cagtaaaaaa
     2101 tttaattact atatatggct tattgtgatt attaagctat cattaccatt tatgaattat
     2161 acttttatat ttaatgagtc aaaatataat ggtaatatta ataagataag tttaggcaat
     2221 tttaatagta tttctattgt atatagtact gttttagtct ctgtttggat tgctattacg
     2281 atattttatt tagtttatac tttattgaaa tatattaagc ttaaaaatat gataaatgat
     2341 ttgtcttatg atgttgagga tgataagata aaaaatcttt atgaaaattt attaaaagag
     2401 cttaagataa ataaaaaaat acggcttaaa tattcatatg aagttgaaag tccagtattt
     2461 tttaattcgt gtgtcatttt accaccatgt gattatacat taaaagagtt aaactggata
     2521 tttaggcatg agttgatgca ttttaagagt aaagaccttt atattaagta tttggtgata
     2581 tttttaaaat gtgtttattg gtttaatcct tttgtgtata taatggagaa gtttatagat
     2641 ttggattgtg aattttattg tgatgaaaga gttttgaaga attgtacgat agaagagaag
     2701 caggattatg cattgacaat aattagtgca atgagaaaag gttcaaatag ttcaaataaa
     2761 tttgtggctg gattacataa ggagtcagat attaaaaaaa gagtgtttag tatgtttaat
     2821 gaaaagtaca gaaatggtat tttgatagca gttattttat gtttattatc ttctattaca
     2881 tattttaaaa ttgatttaat tactactaaa tcaatatttt atccactttc aaaacaaaca
     2941 cctattgaaa acagaactaa ttcaaaacct acatatcaga ttaatgttta tatagataat
     3001 taaaaaatac aaagtttaac aagagattaa tataaataat tttaataagt atctttcaca
     3061 tatgttaaat ttactttaat tatattaaag ccaatgaatt attctttaga agctccaatg
     3121 ccagtaaata caggtaaaga aaaaattact acaattgtag attaaaaatg ttctaatatt
     3181 taaagaaatg caaaagtgta agaagggtaa aaatctgtta taatacatta aaaactaaat
     3241 ttagaaaaat ttacataatt agaaaaatga tttgataaaa aataaagtta aatattaact
     3301 aagtaaattt gaaaaagaaa aaatataaag tacaaattta aaaggaggta actaatgaaa
     3361 aagaagttgg aagatatgac tttagaggag ttatggaact tgtttcctat atttttgact
     3421 actcacaaag aatgttggaa aaattggttt aaagaagaac aatatagact aactggaata
     3481 ttgccaatgc aaaaaattgt tagaataagt catattggaa gtacttctgt gagtacgatt
     3541 tatgccaagc ccattgttga catactgatt gagataattc ctgattataa tatgaaagat
     3601 attaaagatt tgattgagtc gaatggatat atttgtatgt ctgagagcag tagtaggctt
     3661 tcacttaata aagggtatac agtagatggg tttgaagaac gagtttttca tttgcatata
     3721 aggtatgtag gtgataatga tgagttgttt tttagagatt acttaattga ccacccagat
     3781 gttgcaaagg agtatgaaaa acttaagttg gacctttgga agaagtatga gcataatcgt
     3841 gatgcttata cagatagtaa actagatttt gttagggagt ttactgaaaa ggcaaaggtg
     3901 ttgtattcta atagatataa ttagaaatag gtacaattag atatttatct tatatattgt
     3961 attatatttt ttaagaaagt aattaataga aaaagggctt gtttcaaaat ggagagataa
     4021 atcccttttt cattgttgaa aggataaaaa tatatttgat ttcatgtaaa aaagagtgcc
     4081 tcatcaacta aaaagtttat tttgagacac acacattttt actaaggtaa ataaaatatc
     4141 acatttgatt aaattttaag ttaatgaata tatgtgtaaa tatttaatta taagttatta
     4201 taattttaca tagtatcaaa caatctaatt tgtattatat aagataatct aattttagac
     4261 taaaataatc taatataaag aaataaagaa aattcactct cagtataaga aatatccaat
     4321 tttccattgt acttattaac aatttctcta atattctcaa taccatatcc gtgagaatta
     4381 ctatcttttt tatctgaaat aaatagttct tgttttctat tgataggatt taccttgttg
     4441 tttgtcaata aatagctaaa atactccttc tcacaacgtg cctttaatac cacttttcta
     4501 tttgacaaat caggaatttt caaagatgct tctatagcgt tatctaaaga atttgaaaaa
     4561 atagtacata aatctatagg ttctataccc aagtgattgt ctatatctat attaaagtgc
     4621 acatcaacac cattttcttc taaacttgta tgacgaagat ttaaaattga gttaagagct
     4681 tggtttttgc aaaattgttt tccactaaga gtacctatac ctatttttaa ctgattaaaa
     4741 tactttttag ctccagcaat atcttcaatt tctaaatacg attcaatcat ttgaaagtga
     4801 ttattcatat catgtcgcat tttgcgtatt tgaatttgtt gattttctag taagttatag
     4861 tatttttctt ttaggtgatt tgcttgtttt tctatcttca tctttacatt ttcaatcaat
     4921 ggctgtaaaa gaagtatcac accgatattt gccagaattg ctgacaagat gattagataa
     4981 gtgccataag gtaagttgcc taagataata ttcttattac tacccatagg gattaaatta
     5041 gtaggtggca gaataatagc aattaatatt gataaaaatg aagatataca caccatatca
     5101 ataaaaatcc atattttatt tgataagtat tgttttatat tgaccaatct attctttagg
     5161 aaaatatgta ttaaaaacca aaataataat ttaattagag cagaaattat ctggactatt
     5221 gaaagtatta aaatatactc ttttgagtgt ataagttcct catatatagg gttgtttata
     5281 aaaagaaaat taagcccaat tataatagga taaagtatca tgacaactga tattatagga
     5341 attaatttgc ttttgctaca tattataagt agtataaaat atccaaatag tgtaaacaaa
     5401 atatttacgg ggtcggaaag ccatattatc atttgactaa taatagagta gcccaaaatc
     5461 aatatgattt tgaaaatcca atgattccta aagtctataa aataggaagt caacttataa
     5521 agaaaaaagg ctatgaaaat attgattaat attagaataa aatttatgct tgtagagatt
     5581 aaagaataaa tgcccattta atataccttt ctattaatta agattctgga aactaagttt
     5641 taaaaaatta aatcttaaaa attaaaattc tggaaattag atttcaaaga attgattttg
     5701 aaaaataaaa ttctagaaat taagcttcaa aaaattgagt tttaaaagat tgaaatttta
     5761 aaaattaagt ttcaaaaaat taaatttgaa aaaaaactct aaaaactaag cttcaaaaaa
     5821 ttgaattttg aaagattgaa attctagaaa ctaagcttta aaaaattaag t
//
LOCUS       DAEPXW010000163         5738 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.167, whole genome shotgun sequence.
ACCESSION   DAEPXW010000163 DAEPXW010000000
VERSION     DAEPXW010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5738
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.167"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            156..785
                     /locus_tag="KRM55_003512"
     CDS             156..785
                     /locus_tag="KRM55_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1595698.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRSVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(899..2413)
                     /gene="glpK"
                     /locus_tag="KRM55_003513"
     CDS             complement(899..2413)
                     /gene="glpK"
                     /locus_tag="KRM55_003513"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH1595699.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            2657..3199
                     /locus_tag="KRM55_003514"
     CDS             2657..3199
                     /locus_tag="KRM55_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595700.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            3213..5705
                     /locus_tag="KRM55_003515"
     CDS             3213..5705
                     /locus_tag="KRM55_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1595701.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGIFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
BASE COUNT         2139 a          875 c          786 g         1938 t
ORIGIN      
        1 aataaaatca tgtatactaa atgcatgtta aaatattatt ttaaaacatg cacaatattt
       61 gtacatattg tagacatata aacctataaa ttatacaata gtattgttaa gattatatat
      121 ttttttaaca taaattttgt attgggggaa aaacaatgga taaaaactat acgatgccaa
      181 tataccaaaa aatagcgttg gatattgcaa ataaaatata cacgggtgaa atacaagagg
      241 attcagtact atttggacgc tctgttttgg ctggtaaata caatgtatct ccagaaacga
      301 taagaagatc tgtcaaaatt ttagaggaca ttggcgttgt taaaagcata aagggtaaag
      361 gtgttattgt actatctcca gacaaagctt cttcttttat aaaaaaatat agagatatta
      421 caaatatatc atcatataaa tcaacacttt ataatttaat agatactaaa tctaatttag
      481 aaaatgaaat attagatact ataaataaaa ttttagacta ttctaacaga cttgaaataa
      541 tcaatccttt agtgcccgtt cagttcacca taaattctaa ttgcaaatat attggtcaaa
      601 cagctgcaca aactaaattt tggcaaaata caggtgctac aatagttgca attaaaagag
      661 gtgaagaact tataatatct cctggaccat atattgaatt tttagaagga gacattctct
      721 tagtagttgg tgaccaacac atttacaatt ctataccaat gtttttatat gaaaacgaaa
      781 aataaattat ataatttagt atgattatat aaaaatgcaa aattaacaac aaaaaaagag
      841 cttcatattt tacataaagc tctttttaaa ttcaaataaa tttaactttg attaattttt
      901 aaatatccaa ttcatcttct ttttcccagc ttaaagctct cgatacagct tttttccatc
      961 ctttatataa tttacatctc ttctcttcac tcatatttgg attaaactct ttttctactg
     1021 accactttga agtaatttca tttcttccaa tatagaatcc aacagacaac cctgctaaat
     1081 aagcagctcc taaagctgta gtttctacta ttttgggtct atctatatct acatttaata
     1141 tatctgattg aaattgcatt aaaaaattat tattacttgc tccaccatca acttttaatg
     1201 attttagttt taattttgaa tcgttttgca ttgcttctaa aacatccttt gtctgataag
     1261 caattgattc caatgtggct cttactatat gttctttttt tgctcctctt gtaagtccta
     1321 aaattgaacc cctagcatac atatcccaat atggagctcc aagacctgta aatgctggca
     1381 ctacatatac accattagta tcctctaccc tatttgcata catttcacta tcttttgcag
     1441 attcaattat ctttaattca tctctaagcc attgaacaga tgctcctcca ataaatatac
     1501 ttccttctaa tgcatatgtt acttttccat caactcccca agcaattgtt gtaagtaacc
     1561 catgcttaga tttaactatg ttactgcctg tattcataag taagaaacaa cccgttccat
     1621 aagtattttt tgcagtacct tcttcaacac aattttgacc aaataatgct gcttgttggt
     1681 ctccagcaca tcccgcaata ggtattttag ctcctgataa catgcgctca tctgtatgac
     1741 cataaacata gctagaaggt tttactaatg gcaacatgct tattggtatg tccaattctc
     1801 gtaatatatc ctcatcccat tctaaatcat ttatattgta catcattgtt ctagatgcat
     1861 ttgagtaatc tgttacatgt acttttccac gagttaaatt ccatattaac catgtatcta
     1921 tagttccaaa taataactct ccttgttctg ctttttccct agctccttct acattatcta
     1981 atatccattt tacttttgtt gctgaaaagt atgcatctat taaaagacct gttttttctt
     2041 ttattgattc ttccaatcct ttatttttaa gttcatcaca tatttctgac gttctcctac
     2101 actgccatac tattgcgtta taaataggtt taccagtata cctactccaa acaaccgtag
     2161 tctctctttg attagttatc cctattgaag caatttcttc tggtcttata cctgctgttt
     2221 ctataacttc tctcattacc ccactttgtg acccccatat ttccataggg tcatgctcta
     2281 cccatccagc ttttggataa atttgattga actctttttg tgcaattttc actatttcgc
     2341 cttttttatt aaatagtata gctcttgaac tggttgttcc ttggtctaat gccattacat
     2401 acttcttttc catcaccata ttctccttat catataatat ttaatttatt aaaaagaaaa
     2461 atttaatatc acatatttca ataaataatc atacttaagt acaaatttaa tataatagat
     2521 atttagtaag aagacactta ttttctatca tatctatata ataatattat acattatagc
     2581 ttacatattg attaataaat tttaaaggag tataataaac agtgttcata ataattttaa
     2641 taaaagaggt ggtaatatgc caaagatttt agaaaatgta aaagaagata tattaaaagt
     2701 gtctcgggat atgattttag aagaagatta ctcgaatatt agcataagga aaatagctca
     2761 aaggtgtggt ataagtgcag gtacagtgta taattacttt aattcaaaac aagaaataat
     2821 agaatatatc acaaaatctg aatgggattt attgataagg cgaattgaat actccaataa
     2881 aaacactgaa gattacataa aaaaactaaa cattattttt actgaaataa gaaattttat
     2941 aaacaaagtt cataatatcc aatacaatga ctttttaaac acttttgaaa cagagagatt
     3001 ttttgaaatg aaaaaacaca aagacgactt tcatgaacag ctttcaaata aagtatatga
     3061 agctttagaa aaagaaagtt tttttaataa tgacaaatta gtatgcaata tcataataaa
     3121 aatgtttttt tcatattcaa catatcttca tatagaattt gaagatttaa aaccctatat
     3181 tgaaaaatta atacattaag gtggtgttta ccttgaatca taatactagt attaagaaca
     3241 aggacagtaa tccaaaaata tttttagtac ttacacttta tctattaggt atatttatgg
     3301 gagctattga tactggaata gtatcaccag caagaacgat tatacaaaat agccttggag
     3361 taaatgaaaa aacgggaatt tggatgatta ccatatacac attaacatac gcttctgtaa
     3421 ttcctatctc tggaaaatta gcagataaaa taggaagaaa atatgtgtat ctagttagta
     3481 tatttctatt tggtagtggt tcattaatat gtggattatc atcactattt tccaatttct
     3541 atattttatt aattggtcgt gttattcaag caattggtgg tggtggaatc atgccaattg
     3601 ctacagcaga atttggaact accttcccag aaaacaaaag aggcatggct ttaggtttag
     3661 ttggggcaac atatggtatt gccaatattt taggttcaag cattggtagc acaattctaa
     3721 gtatctttgg aactcaaaat tggaagtggc tattttttgt aaaccttcca atttgtttaa
     3781 tcatacttat tggtggaatt ttctgtatta aaaacaataa gtctgaatct aaagaaaaaa
     3841 tagataagct tggtacattg atgttgatat gtataatcgt atcactatta tatggtctta
     3901 tgaatataga cttttttaat tttaaaaatt ctatacaaga tatatcagtt tatccatatt
     3961 tattgacatt tattgtactt atacctattt tcatatttat tgaaaataga gctaaagacc
     4021 ctattttaag ctttgaatat tttttaaatc cgagaatatt gatagtactt attttatctt
     4081 taattgttgg tattggaatg atgggtatgg tattcgttcc acagtatgct gaaaatgcat
     4141 taaagataaa tgctggttct ggtggatatt ttgtagctat attgggatta tttgcaggta
     4201 ttgctgctcc tttaagcgga agacttattg acaagtttgg ggcaaaaaaa atactattac
     4261 taggattttc tgtatctatg ataggctctc tttacctagt tttaattgct ctaaaaacca
     4321 atactgtatt tagtgtatgt gtaagtttaa tatttatggg attaggaatg ggatttacta
     4381 tgggaactcc tctaaactat atgatgttat caaatacaag attagaagaa tctaattcag
     4441 cacttgcaac attatccttg atacgctcaa ttggtacttc aatttctcca gctataatga
     4501 ttggatttat agcacatgca ggattatctg tgcaagataa tattatggac ttagttggaa
     4561 agccctcaac tcctaaaata gttcaacttg aagaacttga aaacatgata gatgacttaa
     4621 aatcagaccc tgaaatggca aaaaatttaa aaaatgtctc tatcccaaat atgaatgata
     4681 cttcaaatat aaatatggac atgacaggtg gcaaacttcc aaaatcctta cttaataaag
     4741 ttcagtcagc agatacaacc aacattacca atataacaaa agaaatatca acaacaatgt
     4801 ttgatgaaaa agttccatct ataattacta aaatacagaa aaatgtacaa aaaggaatag
     4861 atggaacaca aagtggaata aacggtattg aagatggtga aaataaacta aatagtggta
     4921 ttaaaggagt tcaaactggt attgacaata tggtaaaagc tagagctggt attaatcaag
     4981 gaatagatgg tgtaaaaaaa ggtattgctg gtgttgacaa aggtataaaa ggtatggaac
     5041 aaggtcttga aaaacaagat gaggccatca aggaacttac aactgcttat aataaaatac
     5101 ctactacaga aaaaactcct actgataacg aaaataactc aaacgaacaa aaccagagta
     5161 ataccagtaa ttctgaatca gatgacacta agaatgattc tacagaaaat aagaataaca
     5221 attccagcga gaataaacca aatgtaaatg aacaaaaaga aagtttaaat gctcaaatac
     5281 agcaactaaa aaagacaaga gatgacttaa atacaaagtt acaaaaaaat aaaactcaaa
     5341 agaacgaatt aagtaaaaaa ctaagatcaa tggaatctca aaagaaagag ctacaaagca
     5401 agttaaataa ttctataagc caaaagaaag acatggaaaa aagccttgat acaatgcaac
     5461 agcaaaaaaa atcactccaa gcagttttag caaagacaca agaggtaaaa actgaaatac
     5521 caaaggcttt tgataaatca aaattggatt atataaattc catagaaaat aatagaacaa
     5581 aaatagaaaa cacactacaa tctactctaa actcaggatt taaacagatg tatataacag
     5641 tattctgtgt aaatctacta gcatttataa tattattgtt ctataaagaa aataaaacta
     5701 gataaaagag tgttatagta ttatattgta aatttatc
//
LOCUS       DAEPXW010000164         5723 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.168, whole genome shotgun sequence.
ACCESSION   DAEPXW010000164 DAEPXW010000000
VERSION     DAEPXW010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.168"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(130..1872)
                     /locus_tag="KRM55_003516"
     CDS             complement(130..1872)
                     /locus_tag="KRM55_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloendopeptidase"
                     /protein_id="HBH1595702.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            2301..3677
                     /locus_tag="KRM55_003517"
     CDS             2301..3677
                     /locus_tag="KRM55_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBH1595703.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            3988..4659
                     /locus_tag="KRM55_003518"
     CDS             3988..4659
                     /locus_tag="KRM55_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBH1595704.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            4848..5645
                     /locus_tag="KRM55_003519"
     CDS             4848..5645
                     /locus_tag="KRM55_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBH1595705.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         2127 a          683 c          924 g         1989 t
ORIGIN      
        1 aaagacaaga gtcttaaaaa tttctgatac tttaccatat aattttatta aacattaatt
       61 gtgtgtgaaa aaatatcact tatttcaatc taatactaaa tcttaagagt gagtataaag
      121 tattagaaat taagaagcat tttttagttc aagcggatta tctataccaa aataatcata
      181 taaagtagag cttatttcct ctaaatttcc atcttggaaa ggtaattgta aatttacctt
      241 ttctaccaca tctttaaatc cagcatcagt attttgattt aaaaaatcca tatatacatc
      301 aacagctttt ctgtaatctt cttgtgataa ttgccatatc tgaagtgata catcagatgc
      361 aagaccataa ctcaagtaat aaaaaggaac ttggaagtta tgagatacaa gtatccaaaa
      421 aggagcattt ttttctctaa gtatattatt ggaaactcca tattcttcct ctaaatcaaa
      481 aaacaattta ttgatatcat ttagactcat atatggattc ttgtatataa tttcttgaaa
      541 ttcatcataa agacaagcat caataatagt atttaaaaca atcgataagt gttctttttt
      601 tatagcttca gattgtttac caaaaaaatc atcaaaatat ttataaaata gaatttctaa
      661 agatgttgaa tgaacttcac atacatctat acttggttgc atcttattgt ttaagttaat
      721 actgttgtag taattataaa aatgaccaaa ctcatgagca aaactagtaa cacctaaaaa
      781 agaattatcc catgtattaa acaagaaagg tgctttatat ttatttatat aagtagtata
      841 tcctccaggt gatttgtttt ttccagaaga ataatcgtac aagtcatatt ttttcatata
      901 gtcgaagctc tcttttagtt ttggagatat atcttcaagt actttatcaa acttcctaaa
      961 tgagcgattt ttatatactt taatataaat agaagaatca gatggtttag atgaaatctc
     1021 tctatataat ggaactatgt aatcttttac atcttgtcta aattttttag cttcttcttg
     1081 agaatagtct ttgtttaggt tcatataggc ataatctata taattcttaa atccttgctt
     1141 acttgctatt tcagttcttg tctgtataag ttctaagaat atgttaccaa atataggatt
     1201 gtattttttt aagtaatctg aataaatttt cacatattct tcagggctaa gatttggtct
     1261 tgacaaggct tcttcaaagt ctacctctat accatctatt gatactgtag atttagctaa
     1321 taagtcttca tattttacaa ctaggtcttg ctctttttta agcaaacctt caacttcttt
     1381 agaattaagt tttccaatgt tctttagata attaaatgta tcctttccaa gttctttttc
     1441 taattcttta gagaatttag aagttacaaa tctatcttga aagtctttgt atgacatgtc
     1501 aacatctact gatttactca taagatactt atattcctta gagtaaaatt cgtctgatga
     1561 atctatgtta tttctaattt ttgctatagt aagtgtactg taaaaatctt gataaatttt
     1621 atcaacttca ttaaataaat ttaattgttc cttagctgtt ttagctgtta aaagtttgtc
     1681 gttgcacttg ttaatgtttt cgcaaattga ctgtatatta ggacgcttat attccatttt
     1741 ttcaaaagga atagttcctc taacagaatc tttttttgta tcattagtat aatttcttat
     1801 gtatgatgca aatataataa aaactgcaat taaaattaga aaaacaaata ttttcttctt
     1861 ggatttaacc ataaaaatcc tccaatcatg gatatagtta ttaattattt tactatatta
     1921 aatataaaaa atgcatgtta agaaaattta acataaagat atagataaga ttataaataa
     1981 tataaaaaat ttaacttcaa aaaagtatat gaaatttata ctggtaaaat gataaataaa
     2041 ttttaagtac aaaatagtaa aagctatgat agttttagac ctattatatg taaaaaatat
     2101 agatgttttt ggtgcaattt aaattaaaag atatatataa aaatttaaaa tattccaaac
     2161 agaaattata aaaattacta tcattgtctt tatacaatat ttatactata atagaataat
     2221 aatttagagg aaagctctaa aaataaacaa attaagggtc ttaacagtag tgattttatg
     2281 ttaaggaggt ataaagaaag ttgaaaacaa tagttagaag acttattctc tacgcagatg
     2341 gaatgcgtcc tactcaaata atggtatctg ggtttgctgc gattattgta atcggagcat
     2401 tgttgttaac actcccgata gcgtcgcaga gtggagagag tataggctta ttaaatgctc
     2461 tatttacggc tacttcagcg gtttgtgtta ctggtctagt tatggtagat acagcaactt
     2521 attggagttt atttggacag atagttataa taacattgat acaaattggt ggtcttggat
     2581 ttatgaccgt agccacaatg ttttcactta tggcacgaaa aaaaatacaa ctaagagaaa
     2641 gattattaat acaagagtca ttaaatcaag ctgatttatc gggacttgta agacttacaa
     2701 gatttgtatt aataataacc ataacaatag agggaatagg tgcactggtt ttatcaactg
     2761 tctttattcc acaatttggt ttgtctaaag ggatatggta tagtgtattt cacgcaatat
     2821 cagcgttttg taatgccgga tttgacttga tgggcagtgt aagtggccca tttacatcgt
     2881 taaattctta tgtaaacaac tttacagtat caatgactgt ttgcgcactt atagtgcttg
     2941 gagggctagg attccctgtt gtacttgata ttgtaagaaa aagaagattt tcaaaattaa
     3001 atgtgcattc taaggttgta ttgttttcaa ctgctacact tatttttgtg ggtgcattat
     3061 ttatttttct tatagaattt aatcaaaaag ctactatggc ggacttgcct ttaaagggaa
     3121 aagtactatc agcaatattt caatcagtaa cagcaagaac tgctggtttt aatacgcttg
     3181 atttagctac tttacgagaa agtagtgtat ttgtaatgat aattttgatg tttattggag
     3241 catcacctgc atcaactggt gggggtataa aaacaacaac actagctgtt ttaatcatta
     3301 cagttagaag ttttctatca ggaaaatcag atatagaagc ttttgaaaga agattagctc
     3361 catcaactat aaaaaaatct cttggtatat ttgtaatcag tatatcagca gttatttttg
     3421 gaacattgat tatttcaata actcagccta attttacatt agttcaatca gcttttgagg
     3481 ttacatcagc acttgctaca gttggttcaa gtttagctgg aactccaaac ttaaatgctt
     3541 taggtaagat tataataata atctttatgt ttatgggtag agttggttct cttactttat
     3601 ttatggctat actttctggt ggtagaagaa agagtcaacc aatcagatat gcagaaggta
     3661 aaattatggt tggttaagtt accaaggagt agtataaatt tataatgggt ttagagtagc
     3721 actgtaaatc tgttgataaa ataaatgagc ctagatgtaa ttatatgaag aaataaaatc
     3781 aactaatgaa caaaattaat taatgaaata aaaaaacagg gaaataaaat acaaataaaa
     3841 aggtaaatca aaattaaatt aatctgtgtg tataaaatta tatattgtgt ataagttttg
     3901 tatgtgtaaa gtatataagt tttgtatgtg taaacaatta atttaagaga tattatataa
     3961 attgtgtatt agggaggaag tttcgagatg aagcaatata tagtcattgg gtgtgggaga
     4021 tttggaagtt cagttgcgtc tactatgcat cttttaggac atcaagtaat ggcaatagac
     4081 aaaaatgaag attcagttca aagtatatct gacaaggtaa cccattcact tatagtggat
     4141 gttactgatg agcaagcgtt aaggtcatta ggtttaggta actttgatgt agcagtagtt
     4201 gcaataggtt ctgatataag ggcatctata atggcgactc ttatagccaa agaaatgggt
     4261 gtagagttga taatatgtaa ggcaaaggat gaattacaag ctaaagttct ttataaaatt
     4321 ggtgcagata gagttgtatt tccagaaaga gatatgggag taagagttgc acacaattta
     4381 gtttcggata atatattaga ccatattgaa cttgacccag agtattcaat tgttgaaatc
     4441 gtaactccaa atagttgggt tggcaagaca cttatagagc ttgaattaag agctagatat
     4501 gagataactg tacttgctat aaaaacaggt aaaaatataa atgttacacc ttctccagat
     4561 gaggaactta cagccggaag tatcctagtt ataatcggtc aaaatactag tataacagcg
     4621 ataacatctg gaaataaggg gataattaga agaagataat ttactattta atatatattt
     4681 aattgcaatg aaagtagata gtatcatata attatgaata gttatatgat actatttttt
     4741 taatcgaagg tagtatttat ttgtaagatt agataaagag aagttaaatt aaaagtaagg
     4801 aggctgtgct aatataaaaa tttataagtt attagcattt agataaaatg attacaaata
     4861 taaacagtaa ggataatgaa aagttaaagt atacaagagc actattaaaa tcaaagaata
     4921 ggaataaaga gtcaaagttc ataatagaag gatacagaat agtaatgctt gcacttgaat
     4981 gtatggcaaa ccttgattat gtatttatca atgaagaatt tgaaaataag aaagaacatg
     5041 taaaactatt agaagatttg gataaaaaaa acacaaagat atacaagact actaataaaa
     5101 actttaaaga attagtggat acagaaaata ctcaaggaat aataggtgta gtttcattta
     5161 agaaaaaaaa attaagtgaa agtataaata aaaaagataa atttgtattg attttagaca
     5221 gaatacaaga cccaggaaat atggggacta taataaggac tgctgattct gctggagtag
     5281 atgccataat agcactaaag ggatgtgtcg atatatacaa cccaaaagta attaggtcta
     5341 ctatgggttc tatttttgat atgaatataa ttgatgcttc acaagatgaa actgtggaca
     5401 tgcttaaatc attggatttt aatatagttt caagttactt aaatacagaa aatttttatg
     5461 acaaaataga ttatggctca aaagtagcat tggtgatagg aaacgaagca aatggaataa
     5521 atgaagaact tgtatcaaag tctgatattt tggttaagat acctatatat ggtaaagccg
     5581 agtcgttaaa tgctgcgata agctctgcta tactgatgta tgaaataaaa aaatacttaa
     5641 tttaatgtat tgtaataaat ataatgtcat gttataatct tgaattaaat agtagagtat
     5701 caaaaatagt caatatatat taa
//
LOCUS       DAEPXW010000165         5591 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.169, whole genome shotgun sequence.
ACCESSION   DAEPXW010000165 DAEPXW010000000
VERSION     DAEPXW010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5591
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.169"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            20..136
                     /gene="rrf"
                     /locus_tag="KRM55_003520"
     rRNA            20..136
                     /gene="rrf"
                     /locus_tag="KRM55_003520"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(350..1534)
                     /locus_tag="KRM55_003521"
     CDS             complement(350..1534)
                     /locus_tag="KRM55_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1595706.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1907..4258
                     /locus_tag="KRM55_003522"
     CDS             1907..4258
                     /locus_tag="KRM55_003522"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBH1595707.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDNLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4280..4819
                     /gene="nrdG"
                     /locus_tag="KRM55_003523"
     CDS             4280..4819
                     /gene="nrdG"
                     /locus_tag="KRM55_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBH1595708.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2179 a          638 c          903 g         1871 t
ORIGIN      
        1 atattaagca taaagattat gtggttacaa tagcagagag gatacacctg ttcccattcc
       61 gaacacagaa gttaagctct ctagcgctga tggtacttgg tgggaaactg cctgggagag
      121 taggacgtag ccacgtaatt tttttgttat aataaattta gaatttaact tatatagttt
      181 aatttgataa tttgatgaaa aaaataaaag acttactgat ttttaaatct ataggtcttt
      241 tattttttat ctaacattta aattaagttg ttgaatatat cttatattac ttaccttata
      301 tattaattac cattaataca ttatatctaa ttactattca tctaaattac tatgccatta
      361 ttttatatac aaattctttt aatttatcta atccagataa gaaagtattt tcactgcaag
      421 cataggatat acgaatatat ttatccatac caaatgctat gccaggaaca actgcaacat
      481 tatattcttc taaaaattga ttacaaaatt ctatagaaaa actatcttta tattcaaatt
      541 tctcagatac tttagaaaga tctataaata tatagaatgc gccatttgga ttcacatatc
      601 ctacattatc aatagagtct agttttgatt taattaaatc tcttcttgat ttatatgttt
      661 taaccatatt gtctatgtca attgagcaat ctttcaaggc tccataggct atgtattgtg
      721 ctgttagact tgggtgagat ataagatgtc cttgtataga actcattgct ttagcaatcg
      781 ttttattaga tgcagtatat cctaatctta atccagtcat tgcagctgac ttagaaaaac
      841 catttatagt tattgttata tctttagctt cttcgcttaa tgatgcaatt gatgtaaatt
      901 caccagtgta gcatattttt tcatatattt catctgctaa aatatatatt ttattttgta
      961 tgcatacatc tactatttct attaattcat cttttgtata aacactacca gtaggatttg
     1021 aaggattgtt tattacaaga atttttgttt tatctgttat agatttttca agttcttctt
     1081 ttgttaactt aaatccattt tcttttttag tatcaataaa aactggaaca gcattaacta
     1141 acttaatcat ttcaggataa ctaacccaat aaggctttgg taataagact tcatctcctt
     1201 cgtctgttaa agctagtaaa gtatttgtta ttgagttttt tgctccactt gatacaacta
     1261 tttcgtctat tgaatagtta cagttatttt cttcaataag ttttttacag atttcctctc
     1321 taagtatttt taatcctgga actaaatcat atttagtgta atctttattt aaagaatcaa
     1381 taccataaga ttttgcgtta ttaggtacat taaaatcggg ttctcctata ctaagattta
     1441 ttactttaac tccattactt tccatttctt taactttaga actaatacct attgtgtagg
     1501 atggtgttat aaagtttagt ctttttgata acataaaatg cctcctttta aattattatt
     1561 tatattatac gacaaattta aagaatttac ataaggaaat ttgtagatat atacattaat
     1621 atatataata gcctacactt tttgcctaaa attagtgtaa aaaaaagaga aaaaaatttt
     1681 aactttcaaa gttgttagaa acgctgctgt tcaaaatatc cacatagtat ttgcaatgat
     1741 ttgcgcaagt ttgactatta tgtacaaatt tggtaatctt aatatagcaa ttattaagat
     1801 aatcccttta acttagttga aggggatttt tttagactta acatactaca tatagtggta
     1861 tggggattaa taaaatacaa tatatagtaa caggaggttt ttttaattgg ttgaattcgt
     1921 aaaaaaaaga gatggaagag taattccatt taatgaagat agaataacaa gagctatatt
     1981 tttagcagca acgaatgttg cagaaagaga aggaatagta cctgattata aattatctga
     2041 gcaattaact caagaagtaa taaagttttt aaatcataaa tactcagaat cagttccaag
     2101 tgttgaagat atacaagatt ctgtagttaa ggttcttata gaaactggcc atgcaaaaac
     2161 tagtgaagaa tatataatat acagaactga aagaagtaga ataagaaatt caaaaacaag
     2221 gttgatgaag gcaatagagg aaattacctt tgaagatgca gaagatgctg atataaaaag
     2281 agaaaatgca aatattaatg gtaatacagc aatgggaact atgttacaat atggaagcac
     2341 tgtatctaaa gaattttgta aaacacatat attaaaacca gagcattctt ttgctcatga
     2401 taatggagat atacacatac atgatatgga ttttttaaat atgggaacat taacttgttg
     2461 tcaaatagat gttaaaaaac tattcaatgg tggattttca acaggacatg gctttttaag
     2521 agagccacaa gatataataa gttatggtgc attagctgca attgctatac aaagcaatca
     2581 aaacgatcaa catggaggtc aaagtatacc atttttcgat tatggattgg ctgaaggtgt
     2641 atataagaca tttaagaaat tctacatagg aaatttagct aaagcattga agttatttaa
     2701 aggaattgaa aataatgatg tgataaagaa catagtatat aatacagaga aagaaacaaa
     2761 tcaaaaagtt ggtcttaaga gagatgaatt gtatctaaac ttagaaaaag agaaattaat
     2821 acagactttt gatatagatg atgaacttgt aaataagatg caaaactttg catttgaaga
     2881 atcgtataga gaaactgata aaaaaacata tcaatctatg gaagcattta tacacaatct
     2941 aaacacaatg cactctagag caggtgcaca ggtaccattt tcaagtgtaa acttcggaac
     3001 agatacttct gaagaaggaa gaatggtaac taagaatctt ctattatctc aagaaagagg
     3061 tttaggtaat ggagagacac caatttttcc aattttaata tttaaggtca aagaaggcat
     3121 aaatttaaat cctgaagacc ctaattatga tttatttaaa ttatcatgca gagtatcagc
     3181 taaaagacta ttccctaatt ttagcttttt agatgcgcct tttaatgcaa aatattataa
     3241 aaaaggtgaa ccagatacag aggctacata tatgggttgt agaacaagag tacttagtaa
     3301 tgtgtgtggt tcagaaacag ttagtggtag aggaaacata tcttttacta cagtaaattt
     3361 accaagattg ggtataaaac atggtattat aaataatgaa aaggctaatt tagatggttt
     3421 ctttgaagaa ttagatgaga agataaactt aattatagaa caattattgg agcgccttga
     3481 ggttcaagga aataaaaaga tgaagaattt tccattctta atggggcaag gtgtatggaa
     3541 aggttctgat aatttaggac cagaagatac actaaaagaa gtaataaaac aaggaacatt
     3601 gacaattgga tttataggtt tagcagagtg ccttattgct cttataggta aacatcatgg
     3661 agaaagtaaa gaagctcaag aattaggatt aaaaatagtg tcacatatga gacataaaat
     3721 ggatgaagca acggacaaat ataaattaaa tttctcctta atgggtactc cagcagaagg
     3781 tctttcaggt aggtttacta aaatagataa aaaagtttat ggagaaatta aaggtatcac
     3841 agataaagaa tattatacta attcattcca tgtaccagtt tattacaata taagtgcata
     3901 tgataaaatt gagatagaag ctccatacca tgaattgact aatgcaggtc atataacata
     3961 tgtagagtta gatggagatc catctgataa tttagaagct tttgaaactg ttataaaagc
     4021 tatgaaagat ttgggtatag gatatggaag tataaatcat cctgtagata gagacccaat
     4081 atgcggtttt tcaggtgtaa taacaagtaa tatatgccct gtatgtggaa gaaatgaaga
     4141 tgaaagtgac atcaaattcg aaagaataag aagaataaca ggatacttag ttggtacagt
     4201 tgatagattt aataatgcta aaaaagcaga agtaagagat agagtaaaac atagatagtt
     4261 ttatttgggg gaataagtta tgaaaataag aatgtcatct actataagtt atgacagcat
     4321 agttgatgga ccaggattaa gaatggtaat atggactcaa ggatgtattc ataattgtaa
     4381 agagtgccat aatcctcaga cacatgattt atgtggagga ttttatatgg atacagaaga
     4441 aattataaat aaagtcaaat cattgaaatt acaaaaaggc attacgctat caggaggaga
     4501 accattttta caaccagaac cattagaaga aatagcaaga gaagctaaaa taaatgggtt
     4561 agatgtatgg tcatatactg gatttacgtt tgaacaactg ttagataaaa aaaatagagc
     4621 gtattttaaa aatttaaatt tactaaagca aattgatatt ttagtggatg gaaaatttat
     4681 agctgaaaaa aaagatataa gcttaaagtt tagagggtca tcaaatcaaa ggataattga
     4741 tgttcaaaaa agtttgaaat ataaaaaagt gtttttggtt gagcaatata tgaaggatga
     4801 tttatctata gcagaataaa atataaataa acaggattaa atatatgcat atatttaatt
     4861 ctgtttattt tcatataata tttcaagctt gtataatgta acaattaaac caaaagactc
     4921 attgtatatt tgaaattaag ttttttatag tttataggtg ttttatgtgg attacgaatg
     4981 atatagtatc gatacattat ttaatagatt cttatgccaa gaaacaatta atttatagaa
     5041 attcttaatt gttacaatat aaatatctag ataagttata agatactgat aaataattta
     5101 taaagtttat taatctaata ttgtgtgtga atattaagtg gtcaagtagt ctaaaaaatg
     5161 aaaaagattt aaaaaagtgt tttaactaaa cacataagtg ttaaattcat gtataagtat
     5221 aggttagata cataagaaat aattatgtaa tatctatctt tgtaaaaaaa tattaaattt
     5281 tgtaatttgt ggataaatat gtttataatg tggataatat ttaatgtaat aagttaaagc
     5341 aatatgaatc aactgtttat aatgtggata atattataaa tgtatgaata attgcagtat
     5401 ttaaaaacaa aaaaagttaa aaaagttgtt gactctaaaa gaaaaagttg gtatagtaat
     5461 acttgtcctc aagaaaaggg caaacaaata aagcacaaag aactttgaaa attaaacagt
     5521 aggttaattt ataaaacaag aaacaaacca taaagccaga tattttgata acaatagtat
     5581 ctgagcctga t
//
LOCUS       DAEPXW010000166         5435 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.170, whole genome shotgun sequence.
ACCESSION   DAEPXW010000166 DAEPXW010000000
VERSION     DAEPXW010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5435
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.170"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(561..1967)
                     /locus_tag="KRM55_003524"
     CDS             complement(561..1967)
                     /locus_tag="KRM55_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595709.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQTLNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(2012..2719)
                     /locus_tag="KRM55_003525"
     CDS             complement(2012..2719)
                     /locus_tag="KRM55_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595710.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            2890..3804
                     /locus_tag="KRM55_003526"
     CDS             2890..3804
                     /locus_tag="KRM55_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595711.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3804..4565
                     /locus_tag="KRM55_003527"
     CDS             3804..4565
                     /locus_tag="KRM55_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595712.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFAAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            4577..5314
                     /locus_tag="KRM55_003528"
     CDS             4577..5314
                     /locus_tag="KRM55_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595713.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
BASE COUNT         1885 a          840 c          697 g         2013 t
ORIGIN      
        1 caacataaat acatatatat atatgttatt tctaaaaata ctacacaaaa actctacttt
       61 agtagaactc aatggcgcaa aatacttcaa tttaaaacat ttatcgtact ttaaataaat
      121 aactataata aaatatactt acaatagtta catagaagct attataacta cacagaacag
      181 cttataatta aaactttttt aggatgtcat tatatttttt cttaaaatta aaaaacacta
      241 taccataatt ctattttagt agaatttttt tgtcaataat aaaattaaat attaactaaa
      301 aaataaaaaa aatggaatta tctaaagaat ttaataacct tacaataatt ccaaaatatt
      361 atttctatga aaattttgat accatgagta actcagccat aagcgcataa agcacaagtt
      421 actctttact ttaataaaac ttgacaagaa aagaatttat ccttattcta ctctaataga
      481 gttaatttgt caataaagaa taaaattatt ttcaaaatat tttcattctt cattcttatc
      541 tgttattatt ttataaaata tcacttaatt agaggtaatt ttagtattgt ttttagtccc
      601 tgactatcaa tgctcgtaat atctaattta cctctatgtg cattaataat gccagatact
      661 atcaaaatac ctagaccatg attttgacct ttggcatatg cctcacttag tccattttgg
      721 ctctttaata aactattaat tctttcttga ctcatacctt ttccatcatc ttcaacaatt
      781 atatagcaaa aatctaaatc agacttagag gtaaccctta tattacatcc ttgttggtta
      841 tgagttatac tattttgtat taaattacta atagcccttt ttaataattt tttatctgca
      901 tctataataa tatcttcatt tagtatatca agttcaacgt aaaagtcatt atccaaatta
      961 ttatttataa actcagaaat aagctctctc aaaaacgcag aaactctaat cttatcacaa
     1021 ttcaatgttt gcatattata ttcaagttta gacactaaat ttaggtcatt tactaattct
     1081 ctgattttaa tcccttgatt gcatataata gacacttgct cttgttctct atttgaaagg
     1141 ctactgcttt cttcaagttc tccagcatat ccaattatca ttgaaagtgg agttcttata
     1201 tcatgagata ttcctgcaat ccagttagac ctagcttcct ctttcttcct aagtttttca
     1261 tctttcattt gcaactcttt agatacagta ttaatagatt ttgaaatatc acttagtatt
     1321 cctttttctt gtaaaagtac tggttctcct tttgacataa gctttatgcc agtaataatt
     1381 ggttttatag atttcaccat ttttaaacct atgaatagag ctattaaaaa agtaactatt
     1441 gcattaacca gaaacatacc tattattaac ataggaaatt gttctatttc cttaaccgta
     1501 taagtaaggt taaacttagt atacttgtct tttggataac ctgttactaa tattccattt
     1561 ggatgttccc atacatacac aggatagtcc tttaaaaaga accttgaaaa ctttgctaca
     1621 tctgtcaaag tataatgact tggaatttct tttggtaaat caaatcccca tattctatct
     1681 ccattgttat caattaacat tgcccaaact ttatttttat gtagtacttc cttactagaa
     1741 tcatctaaaa taaactttcc atctcttaaa atcaaattat cttcaatcat aatcaagttt
     1801 gattttattt ctctactatc acttgtatct aaattatcag agtatttaga tacaaataac
     1861 atatatgaaa acagaagaaa acctgctata tttaatacaa taaaaagtaa tgaaatcaag
     1921 atacttgaac ctataaatcg cctcaatatg tactttacac tatccaaaat taaatcactc
     1981 ctcttgattt cttttattct aatatctaaa attaattaat catcaactta tatccaagac
     2041 ctcttactgt aataagatgt ttaggtgtag atggagtttt ttctatcttc tctctaaccc
     2101 ttctaacatg aaccataagg gtattttcat atccatacat atcatctccc caaatggctt
     2161 gacatagtga atcattagta acaattctcc ctttattttc atacaacttt aaaagcaacg
     2221 aatgctcttt agctgttaaa gaaatctctt gcccatcttt ctcaacacat gcactattta
     2281 aattcacaac aacagaatct cccagtttaa atactggcaa ctcctcttct tctataggca
     2341 catatacacg atttaatata cccacaagcc ttaaagtaag ttcctttggt aaaaatggct
     2401 ttactatata atcgtcagcc cctaagccca aaccaatcaa tctatcttca tcttcacctc
     2461 ttgcagagag aaaaatcact ggtattttag atgtctctct aatttttctc ataatagaaa
     2521 aaccatctcc atctggcaat acaacatcta aaattgcaca atctggcttt acatttctaa
     2581 ataccctaac agcttcctca taacttgatg ctaaaaatac tctactaaat ccctcttttc
     2641 tcaggatttc atctatcatt tttaataatt ccttgtggtc atcaaccaca agtatttttt
     2701 tatcttttat tgactccata atcatcaccc tcctttagta taccatatac ccattttcac
     2761 aactttgcct aaatagactt ttaaggttat tgtaaggtaa atttcagcta attgaaatgt
     2821 aaccaagtta ttatactgat ataagttaaa agaatcaata agcacagatt aaaaaagggg
     2881 atgaaacata tggaaatgat aattagaaca caaagacttt caaaggaata caataaaata
     2941 tttagagtaa aggatataga cctaagagtt ccacaaggag ctgtatatgg ttttttgggt
     3001 cctaatggag ctggaaaatc taccactctt aaaatgcttc ttggacttgc taaacccaca
     3061 caaggaaata ttaatatttt aggtaaagag ttaaatgaaa aaaatagaat atcaatttta
     3121 aaagatatag gttctttgat agaatctcca tcatactatg gtcatcttac agggcttgaa
     3181 aacatgacca taatgcaaag actcttagat ttacctaaaa aaaatgtaaa tgaagcatta
     3241 aaaattgtaa ggttagaaaa tcaaaaaaat aaaaaagtta gtcaatattc tttaggtatg
     3301 aagcaacgtc ttggcattgc tatggcaata atgaagtttc ccaaattatt aatacttgat
     3361 gaacctacaa atggactcga cccagcaggg attgaggaaa ttagagaatt aataaaatct
     3421 ctaccagaaa aatacgggat gactgttcta atctctagcc atcttttaag tgaaattgac
     3481 caaattgcca catcaatagg aataataaat catggcgaac tggtttttca agatagcata
     3541 aaagaacttc ataatagagg tcaaagtcag attgctatca aaactaagaa tgttgtatct
     3601 gcacaaaaac tattaaatac taaaggatat atgtcactta tacaagatgg gtacttgact
     3661 attgaaaatt taaaagactc agatgtcgct aaaataaatg gtatgcttgt ccattcaaat
     3721 atagatgtat ttagaataga agaacataaa aaaagcttag aagatatatt cttagaactt
     3781 actggtaagg cggtgacttt ataatgaaat accttggtct agaattttat aaacttaaaa
     3841 gaaagaagat tattctgatg acctttttat ttgcagctgt tgaaataatg tggtgtatcg
     3901 taaattcaaa tagagctatt acacgtaatc cagatatgtt aggtggattt gaatattcct
     3961 atatgcttat gagttttgca agtttaaatg gtctattctt tcctatctta atatcaataa
     4021 ttacatcacg tataagcgat atagaacata aaggagatac atggaagctt ttaaaatctt
     4081 ctgtgacatc tttaaatagt atttatttat ctaaattttt atgttctgct attttggtat
     4141 ctatacctgt attgatgcaa gtgttatcta ttgtgttgtt tggacatttt agaggggtta
     4201 ttgagtcaat ttctgtatct ttacttttaa aatacacatt aggaacaatt cttgtaagta
     4261 ttgctatcat tgcactacac ctatggattg caactgtaat tccaaatcaa atgattgcaa
     4321 ttacatttgg catgattggt agttttatag gtttgacatc aggtttgttt tatcaaggta
     4381 ttcgtagatt gtttatatgg tcttattacc tagagttatc acctttaagt tatgcttatg
     4441 ataatgtttt aggttcatct gtctatagaa ttgatatgaa tttttctatt acgattttag
     4501 ttttcttaat tggaatgcta atttattata ttggaagaaa tcatttatta aaaaaagaag
     4561 tataggaggg atttaaatgt taaggaagtc agttttggga gaaattctaa agttaaaaaa
     4621 ttcttttata tggtatgtat tattagcttt gccacttata agtgtgttga ttggttctgg
     4681 taatttttat ctaaatcaag gcatactcaa aaaagaatgg tacagcttat ggactcaagt
     4741 tagtcttttt tatggggaat ttttctttcc tatcttaatc gcaatctttt gtgcatatat
     4801 ttgtaggctt gaacatatga atcataattg gaataatgta atgacactgc cagttaattt
     4861 aaaaaatatc tttttatcta aacttacagt agtttcaata cttacagcta ttacacaagt
     4921 tttctttgtt atcttttata tagttgcagg aaatatgttt ggtttttctg gtagtgtacc
     4981 taaagaattg actggttgga ttgctaaagg ttggattatt tctatttcaa tagcttctat
     5041 acaattatac atgtctataa agattagaag ttttgcaact cctattggta ttagtctttg
     5101 cctttctcta tttggtatgg gattaatagt agcaaaacct gctgttggta tatttttccc
     5161 ttattctatg ttaggtagtg ctatgggggt tataaagcaa tctgctttaa atgttaatga
     5221 cactatagtt acaatatgtg ttgcatttat tactactata gtattttctg aaattgccaa
     5281 tagaaatttt agaaagaatg atgttatttc ttaatggtaa atgctagata tttttgggtt
     5341 tgaaatttat attcttttta gttgaaatct atatccattt tatttaaaaa tatatatctt
     5401 ttatttgaat tttatatgtt ttatctactc gctat
//
LOCUS       DAEPXW010000167         5415 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.171, whole genome shotgun sequence.
ACCESSION   DAEPXW010000167 DAEPXW010000000
VERSION     DAEPXW010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5415
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.171"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(269..985)
                     /gene="dapD"
                     /locus_tag="KRM55_003529"
     CDS             complement(269..985)
                     /gene="dapD"
                     /locus_tag="KRM55_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBH1595714.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     NNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(1209..1958)
                     /locus_tag="KRM55_003530"
     CDS             complement(1209..1958)
                     /locus_tag="KRM55_003530"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH1595715.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(2025..2912)
                     /locus_tag="KRM55_003531"
     CDS             complement(2025..2912)
                     /locus_tag="KRM55_003531"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1595716.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(3029..4030)
                     /locus_tag="KRM55_003532"
     CDS             complement(3029..4030)
                     /locus_tag="KRM55_003532"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBH1595717.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(4455..5336)
                     /locus_tag="KRM55_003533"
     CDS             complement(4455..5336)
                     /locus_tag="KRM55_003533"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1595718.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
BASE COUNT         1789 a          972 c          656 g         1998 t
ORIGIN      
        1 cactttatta aattataaaa agtttaatag tttattacat tgatatattg aaaaattgaa
       61 ggaaataaaa atacttgtca gcaagaaata aaaatgatat aagaatgaat aagagaattg
      121 taaaaaaata aaatgattat aaataaaaga taaaaatatt gtaaaaaaga gggtgcctct
      181 ggtgaattaa attcacacag agacaccttt ttaattaatt ttttaaatta gtatattatt
      241 gtttaattaa tagtatagta ctatttaatt agtctaaatt tctaaggtct tccataagct
      301 tagttttgtc agctgttttt tcatccttca tttttataac tttagcagga gaaccagcaa
      361 caacagcacc agcttctaca tcagtagtta caacagcacc agctgcaaca acagcacctt
      421 taccgattct aacaccttca agaataactg cattagctcc tattaaaaca tcatcttcaa
      481 ctataacagg agtagcagaa ggtggctcta aaacaccagc aacaacagca ccagcaccta
      541 agtgaacatt tttaccaaga gttcctctag ctccaataac agcattcata tctaccatag
      601 aaccttcacc aataacagct cctatattta taacagctcc catcattaca acagcatttt
      661 tttctatagt aaccatgtct cttattattg cacctggctc aattcttgca tgttcactta
      721 aagtattttt tagaggaata gcagaatttc ttctatcata ttctacatga gtatctgtta
      781 tatcatttcc atgtttatct aatacttcca ttatatcctc atagtcacct acaaatatat
      841 aagaaccatt atttccaaat accttaaatt tatcagttga ttggaagtgt aaagagttag
      901 tatttacata taccttaaca ggtgttttct ttttaacttc ttttatatac cttgctattt
      961 cataagcatc gtttaaattt accatttgtt aattctcctt gtatttcatt atatttcttt
     1021 tattatatac ttatttgtca attttagtat atacttactt cttattattt atattttatt
     1081 ttagttagtt tttattgtat agacatagta ttaaataaat ttattatata tgtttgattt
     1141 gtattgcgta ttattatatc tatattgtat atgtttaatt tatattgtgt attattatat
     1201 ttatactatt atcccaacat gctgtccata ttataaaatc ctggtttttg cttaactaag
     1261 tatttggcag cagctataga accacttgca aagataccac gagattgagc ttgatggctt
     1321 attgtaagaa cctcattgtc tccagcaaat agagcatcat gttcgccaac aatatttcca
     1381 cctcttatag catgaatacc aacttcattt ggttgtcttt ttgcactacg accatatcta
     1441 ccataattat tttcaacgtt tggcaaaacc tcttttatag cgttagcaat cataacagct
     1501 gtgccacttg gggcatctac ttttctgttg tgatgttttt ctattatttc tatatcaaat
     1561 ccttctagta atttagctgc atctttaacc aattttacta atacatttac accaagagac
     1621 atattatatg attggaatac aggaataact ttagccgctt cacgtatttt gttcatttcg
     1681 tcatcattat atccagtagt agcaattact aaaggtgttt tagtctttaa aacgtaagat
     1741 aagatattat ctaaattaga gtgatgagaa aaatctataa ctacatcagc ttcctcaact
     1801 atagtactca tatcttcata aattttaagg tcgccttcat agctatccag acctctagct
     1861 gcaacacaaa ccaattctaa ttcattatct tctcttatag tatcggctaa aatcttaccc
     1921 atttttccat cataaccagt tgctataact tttaacataa tttcctccta tgattaaggg
     1981 ctaacttttg accaaactta ctttttacca tgcattaatc tttactatgc attaactttt
     2041 agtccaaagt taactaattc tttctttaat acttctaaat ttgctgggtc catttctgct
     2101 agaggtaatc ttaaatctcc aacattgaat cccaataaat tcattgcagt cttaactggt
     2161 ataggattta cttctataaa taaagctgcg attagagcat ccataccaag ttgtaatttt
     2221 ctagaacctt caatatcgcc ttcaaagaat ttagctacca aatcgtgagt ttcttgaggg
     2281 caaacattag caagtactga tataactcct tgacctccta aagataataa aggaagtata
     2341 gtatcatcat taccagagta gatagcaaag tcatctggaa ctaaactagc tatttctgca
     2401 acctgtccta ggtctccact agcttctttt acagcaacta tgttatcaat tttagcaagt
     2461 tcaactataa ggctaggact tatatttaca caagttcttc cagggacatt gtaaagtata
     2521 attggaagtt taacactgtt agctattgtt tcaaaatgac gcttaagtcc agctttatta
     2581 gctttattgt aataaggtgt tattattaat agagcatcta ctcctaattt ttcagcttct
     2641 tgacttaagt taactgagtg catagtatca ttagaaccac ttccagctat aacaggaact
     2701 cttttattaa ctttttcaac aacatactta atagtagcaa gttgttcttc atcagtcata
     2761 gtattagctt caccagtagt accacaagat actatagcat cagtaccatt agctatttgg
     2821 tattcaacta attcacctaa tttgtcaaaa tcaactttgt tatcctttgt aaatggtgta
     2881 actagagcaa cagcagaacc tttaaatatc atataaaatc aatcccctct tttttatttt
     2941 tgtgttttat attacagtta cttctaatgc ttgtttttga gttactatta atattttaca
     3001 aaattatata tttatacaag tttgtatatt atactaaatc gtatgataaa gccatttcag
     3061 ctatttgaat tgcgttagtt gcagcacctt ttcttatatt atcagcaaca acccaaagat
     3121 ttacaccatt atcaacacta aaatctcttc ttattcttcc aacaaatact tcatctctat
     3181 catcaaattc tacagcagtt ggatattcgt ttttagcagg attatcaact actacaacac
     3241 ctggagcttc ttcaagtgtt tttactaaat catctaactc aaatggattg ttaaactcaa
     3301 catttataga ttcactatga ccatttttta ctggaactct tacagtagtt gcagttattt
     3361 ttaaatcgta gttatcaagt attttcatag tttcatttac cattttcatt tcttctttag
     3421 tgtatccatt ttcagtgaat gaatctatat gaggaagaca gttgtaagag atttgatgag
     3481 ggtagaatcc agtaggatta ccgttcattc ctttctctaa atcttcaaca cctttaacac
     3541 cagaaccaga tacagcttgg taagtagagt aaacaactct cttaattttg tatttatcat
     3601 caagagcttt aaggggaacc atagcttgta tagtagagca gttaggatta gctattatac
     3661 ccttatgatt ttttatggct tctggattaa cctcaggaac tactaaaggc acatctggat
     3721 tcattctcca ttgactagag ttatctacta ctaagattcc atttgaagca gctattggag
     3781 catacttttc actaatactt ccaccagcag agaataatgc tatttgtatg cctctatcag
     3841 taaatgaagt ttcctttaat tcttctacta tatattcttt accacaaaac attactttag
     3901 aaccagctga tttagaagaa gagaataaaa atagattttc tattggaaaa tttctttctt
     3961 ctaatacttt taaaaatgtt ctacctacca ttccagtagc accaactatt gctacattta
     4021 cttttttcat ataaattcac cccaatttta aattattaaa acattatttt attttagtta
     4081 tacaagtaag atatgttaat atttttatat atccaaaaac tttaatatta tattaacaac
     4141 tttaattata tacaaaaaac gtacaaaggt atactttgta cgtctaattt atcactcaaa
     4201 gtaaaccctg tagctcatca cctacaaaaa taagtgacag tattacacat gttatgtgca
     4261 atcccagaaa atattattgc aagaaatatt ttcttcggct gtaaatcctt tttccaatca
     4321 ttaacacctg ccagctacta ttggatactc ttagttacag ctacctctac cctaggttaa
     4381 taggatatta aaatttgatt attctaataa taatacatat ttaagaaaaa atcaacttat
     4441 ttatataaat attgctaaaa tttaaatcca aaatttgtca attcttgttt taacacatta
     4501 agattagttt cttccatttc agctagagga agtcttaaat caccaacatt aaaacctaaa
     4561 atgttcatgg cagttttaac aggaactgga tttacttcta taaataaggc agcaattaaa
     4621 gcatccatat caagttgtaa tttttttgag ccttcaatat caccttcaaa gaatttagtt
     4681 actaaatcat gtgtttcttt aggacatatg ttagcaagta cagagataac accacttcca
     4741 cctaatgata atagtggtag tatagtatca tcattaccgg agtatatagc aaagtcttta
     4801 ggtactaatt tagctatttc tgcaacttga gctaagtctc cacttgcttc cttcacagca
     4861 actatattat ctattttagc aagttcagcc acaacagatg gctttatatt cactttagtt
     4921 cttcctggta cgttgtataa aataattggc aacttaacgc tatttgctat tgtttcaaag
     4981 tgaagtttaa gacctttctc attagtctta ttatagtaag gagttattat taaaagacca
     5041 tccaccccta atttttcagc ttcttgactc atatgaacag acaacatagt attgtttgaa
     5101 ccagtacctg ctataacagg tattctctta ttaacttttt caactgtata ttttattaca
     5161 gcaaaaattt cagattcact catagtagtc gcctcacctg ttgttccaca aacaactagt
     5221 gcatctgtgc cattctcaat gtgatattcg attaattcac ctaatttttc aaagttgaca
     5281 ttattatcct ctgtaaatgg ggtaactaaa gcaacagcag aacctttaaa taacatataa
     5341 tcaaatctcc ttttttatct aaatttaatt ttttaagtac aataataatt atagtacaaa
     5401 ttaattaatt ttaat
//
LOCUS       DAEPXW010000168         5393 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.172, whole genome shotgun sequence.
ACCESSION   DAEPXW010000168 DAEPXW010000000
VERSION     DAEPXW010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5393
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.172"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(766..2901)
                     /gene="rnr"
                     /locus_tag="KRM55_003534"
     CDS             complement(766..2901)
                     /gene="rnr"
                     /locus_tag="KRM55_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBH1595719.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3496..4110
                     /locus_tag="KRM55_003535"
     CDS             3496..4110
                     /locus_tag="KRM55_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH1595720.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDLWDISNKKVEFVYKLASKCILAK"
     gene            4128..4490
                     /locus_tag="KRM55_003536"
     CDS             4128..4490
                     /locus_tag="KRM55_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595721.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4596..5093
                     /locus_tag="KRM55_003537"
     CDS             4596..5093
                     /locus_tag="KRM55_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBH1595722.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTVLDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1766 a          808 c          633 g         2186 t
ORIGIN      
        1 ttctaaaaaa gaaaagttat cttaaataaa aaataagtgt atcttaaatt ttaaatgata
       61 cacttatttt tatattgaaa ttatattttt taatatctat tcttaattag gtatttttaa
      121 attatctgtt tacattaaat atttcttaat tacttatctt tcagctagct ttttctatta
      181 aatgtttctc aattacttat ttttcaatta gccacttcta ttaagcattt cttaattact
      241 tatttttcaa ttagtcactt ctattaaaca tttcttaatt atttattttt caattagcca
      301 cttctattaa gcatttctta attacttatt tttcaattag ccacttctat taagcatttc
      361 tcaattactt atttttcaat tagccacttc tattaagcat ttcttaatta cttatttttc
      421 aattagccac ttctattaag catttcttaa ttacttattt ttcaattagc cacttctatt
      481 aaacatttct taattattta tttttcagtt ggctttttct attaaatgtt tcttaattac
      541 ttatctttca gttagctctt tctattaaac atttctcaat tacttatttt tcaattagct
      601 actttcatta aatatttctt aattatttat ctttcagtta actatttcca ttagatattt
      661 ctcaattacc tatttttatc atttatttta tagagtattg tgcactatat atttatacat
      721 atcataaata ctacaacttg ttatctctta ttttagctgt tttatctact cctctatttt
      781 ttcaactatc tcaaagtcaa tttctttaaa atctacatta acactttcaa cctttatctt
      841 aacaaggtca cctatcttat atgacttctt agttctttct cctaaaacac tataagaact
      901 ctcatcataa atatagtaat catcattcat atttgcaagt cttatcaacc cttctatggt
      961 attatctaac tcaacaaata ttccaaatga agttacgcta gatacaacac cctcaaattc
     1021 ttgaccaact ttatccttca tataaagagc cttatagaaa tcatgtacat ctctttcagc
     1081 taactctgcc tttctttctt tctcggatga ttgaacagat gcataatcca ctatagtagt
     1141 aagctgttct tgtctttttc cacttatttt attatttaaa gattctttta ttattctatg
     1201 aatttgaagg tcaggatatc ttcttattgg tgaagtaaag tgacagtaga atttagctgc
     1261 taatccaaaa tgtccactac attctggtga gtacttagct tgttttaaag aacgaagcat
     1321 tatagtactg atagctcctt cttctttttt gccctttatt ttctctatta taccttgtaa
     1381 tgcttttgga tgtacttcct ctttatcacc ttttattata tatccaaatg tagatataaa
     1441 cttactcaat tcttccattt tttccaaaga tggtgtctca tgtattctat acacaaacgg
     1501 tattcccatc cagtaaaaat gttcggcaat tgtctcatta cttataagca taaattcttc
     1561 tattatctta ttagatattc ttctttcata tggctttata tctacaactt cgccttttcc
     1621 atttagaatt atctttgcct ctgggaaatt gaagtctata gctcctcttt tttcccttct
     1681 tgacataaga atcctagcta aaatttcagc atttttaaaa tcttcaacaa catgttcaaa
     1741 agtcttttta agtttttcat catccttttc taatatatca gatacttctg tataagtcat
     1801 tctagctttt gaatttatta cagattcaca tatttcatgt ttaaccacat ttcctttatg
     1861 gtctatttcc ataaatatag aaagagttag cttatcttca aatggattta agctacatac
     1921 tccatttgaa agagtttttg gcaacattgg aattacttta tctactaaat aaactgatgt
     1981 agctcttttt aaggcttcct tgtcaagttt atttttctct cttacataat gtgtaacatc
     2041 agctatgtga actcctagtt tgaagtttcc attaggtaat acttctattg atatggcatc
     2101 atctaagtct tttgcgtcat ctccatctat agtaaatatg tttaaatctc ttaaatctct
     2161 tcttcttttt atctcttctt gaggaatctc aacagctaca gcttctgctt cttgcaatac
     2221 tttctttgga aattcttctg gaagaccatg ttctcttatt atagaatcta tttctacgcc
     2281 tctttcacct ttttgaccta gtatctctat aattttgcct tctggttttc tatcctcttg
     2341 tggccatact gtaatttcac atactacctt atcattatct actgctccac taaaatgttt
     2401 tttaggtata tatatatctt tagtaaattt cttgttgtct ggtgttacaa atccaaaagt
     2461 tttacttgat tggaaggtac ctactattct agttatttct ctctttatta cttttactat
     2521 tcttccttct gctctctttt cttcagttgc aggtactact atttctgcca taactctatc
     2581 attatgcata gcaccattta tattgtcact tgagataaat aaatcctgtg tatattcaac
     2641 atcagattct acaaatccaa aacccttttt gtgtgataca aattttccaa caaagtatcc
     2701 catttgattg ggagatacta tttttccttt tttagtaaag cagatataac catcttcttc
     2761 taattcattt aaaaaattat aaaacattgg catttctgat gaatgtatat caaatatttc
     2821 tgctaattct tcttttttta gaggattata tgcactttca tttattaatc ctagcaaact
     2881 ttctttaagt cctggtatca tttttccctc ctgttttact tttcattata ttattattta
     2941 tattgtcttt tatatttctt cagacaaaac attttttact tatcacataa ttttctatat
     3001 ttccttatta ttattacaag ttaaaattac ttatttatat ttttgattta atgtagcttt
     3061 gtcatactaa cttcaaacaa attatgatat tttataaatt atttgtaaat atcattataa
     3121 ttacttaagt tattctttat cataattgct taaattactc tttatcacct aattatacac
     3181 catcaaatag gattggtaaa atattcatct catataagta ttactatata ataatttatt
     3241 ctattagtat actcaaatca tgtaaaattt atataactca attaattttt taaatacaac
     3301 tttataatat aaaacttata ataaaagtaa atttatatgt taaatgaggt tgatttttta
     3361 ttatttttta tttatgctag tactaaagac ttgcaaacgt tttttgacaa gtctttattt
     3421 tgtctaaatt aaacaaactt ttttacaaat aaatacataa aatttaaact aatctattta
     3481 ttggaggaga taaaattgga agaagtaatt gcaaaaatta ttactataga aaatggattc
     3541 aaagaaattg aaaatattgc taaaaaaatt gtaaaaaata atgactcaaa aaagtgttat
     3601 tatctatcaa tctacttata taggtcagaa tattatcaag taagagaatt ggctgtgttt
     3661 atacttggtt ttatatcagt aactatttct gaagctttgt tatttttaaa agacaatgtg
     3721 agtaaagatg aaaactggag agtacaagaa atactagcta aatcatttga ttattattgc
     3781 agtgaagtag gatatgaaaa ggctcttcct gttataaaag aatggcttaa ttctgatagt
     3841 ccaaacataa aaagggctgt gacagaaggt cttcgaattt ggactagtag agactatttt
     3901 aaatctaatc ctgacgttgc tatatcacta ctttctagtt taaaagaaga tgatagtgaa
     3961 tacttgagaa agtctgtagg taatgctctt agagatataa gtaaaaaata tccagattta
     4021 gtaaaaaaag aattagattt atgggatata tcaaataaaa aagttgagtt tgtatataag
     4081 cttgcttcaa aatgtatctt ggcaaagtaa aatggaggtg aacttatttg aaacttcgtg
     4141 atgagtatac ttgcccatta gaactaacac atgatatgat aaaaggcaaa tggaaatcta
     4201 ttatattatg gagattacgc ataggaccaa cttccttatc aaaacttgaa aaggaaatca
     4261 atggtattaa tcaaaagatg ttacttgaac aacttaaaga attaattgaa tttggtcttg
     4321 tagataaaaa gacatatgaa ggttacccac ttaaagttga atactcactt acacctattc
     4381 gagggaaaca aatattggat gctttggcta taatgcaaga tataggaatt agctttatgt
     4441 tggataatgg tatggaagat attcttaagg aaaaaggtgt tttaaagtaa atagataccc
     4501 acaaaaaagt aagtaattta ccattatttt caactggtat ataattaaat tatagatata
     4561 ttctattaat ttattataat aggaggtaaa ttattatgaa agtaactagt acaggtatag
     4621 taaatggtgt tatagaagat aaatacggta aaaggggaac tcagttcaat gaaggtggta
     4681 tgcctaccta ttcactacct ctaaagtttg aagatgctcc aaagaataca gtatcctttg
     4741 ctgtattttt agaagataaa gactctgttc ctgtatgtgg gtttgcatgg atacattggt
     4801 tagctgtaaa tataacaaaa gatgagttaa atgaaaatga aagtgtaaca gctactgatt
     4861 ttgtacaagg gactactagt tggcatggca aactaggagg tcttgacaga ttagaggcca
     4921 gtgtatatgg tggaatggct cctccagaca gacctcatgt ctatgaaata catgtatttg
     4981 cacttgatac tgttcttgac cttgaaaaag gattctatat gaatgaattt ttcaaagcta
     5041 ttgaagggca tgttttagat acatttacac taaaaggaag ttattctaat taattaggtt
     5101 gactatagct aatcattaat taaatgctac atttaattga tgattagctt aattgttatt
     5161 agaatatttt ctgcacttta tcttaatata tattttagtt gactggtatt ttaatttcta
     5221 ttagattatt atcaatttat ataaattgat tttagcttaa aacttactta tctatttcag
     5281 tttctattag aattattatt agactcatta aaataaaagc attaatataa ctaataatat
     5341 atgttaaatt cattaaatct acataaagtt ttataatcta aatgaaatac aat
//
LOCUS       DAEPXW010000169         5320 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.173, whole genome shotgun sequence.
ACCESSION   DAEPXW010000169 DAEPXW010000000
VERSION     DAEPXW010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5320
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.173"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            103..834
                     /locus_tag="KRM55_003538"
     CDS             103..834
                     /locus_tag="KRM55_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595723.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
     gene            complement(991..1197)
                     /locus_tag="KRM55_003539"
     CDS             complement(991..1197)
                     /locus_tag="KRM55_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595724.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(1599..1994)
                     /locus_tag="KRM55_003540"
     CDS             complement(1599..1994)
                     /locus_tag="KRM55_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH1595725.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            2135..2527
                     /locus_tag="KRM55_003541"
     CDS             2135..2527
                     /locus_tag="KRM55_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595726.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            complement(2621..3037)
                     /locus_tag="KRM55_003542"
     CDS             complement(2621..3037)
                     /locus_tag="KRM55_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH1595727.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(3052..3963)
                     /locus_tag="KRM55_003543"
     CDS             complement(3052..3963)
                     /locus_tag="KRM55_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1595728.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            complement(4145..5167)
                     /gene="splB"
                     /locus_tag="KRM55_003544"
     CDS             complement(4145..5167)
                     /gene="splB"
                     /locus_tag="KRM55_003544"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBH1595729.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
BASE COUNT         1898 a          812 c          596 g         2014 t
ORIGIN      
        1 atattctatt ataatcttta gaacaaacag tagtaaatgt tatcttcata aacaaattta
       61 tttttcacaa gtacaatact tatttaaaaa aggaggttta atatgttaag taaaaaaaat
      121 gtaagtttaa ttattttagt aataatttta agtttattaa ctgctatatt tattttcaat
      181 aataaaaata ctaacaataa attgaaagaa gttactaaga ataatgaaga aatagtacct
      241 aaaaacttag aaggtttaag tatagaacaa ttaatagaga ttagagataa agccattgat
      301 aaaaatttag aaggtcttag ggaatttgga gaagattcag taaaaaaacg taaagattca
      361 attttaaact ttgaatttgg attagtagct tttgttaaca agaattatag caacttaaca
      421 gaaaaagaga aattaataag acaaattaat attgttaact atgaaaactc tataaatgat
      481 ataatggatc cttcaggttc attctttgaa ttagcaaatc agaattacca agtgaatgag
      541 tttctgttaa aaaacggaaa agattataaa gaatggtcat atgaaggtct agattttcta
      601 attgatcatc tagaagaact gtgcaaattt gttgattttg atgtaaaaga tgtaatagat
      661 attattgatc ctacaataaa aacagatctt tcagaggaac aaaagaaatc tttgaatgat
      721 aaattaaaga aaatatcttc aagtgatact ttaagtgaag aagttaaaaa ggagataaaa
      781 aactgggaaa acaatttaaa taatttaaat atgaataaaa ataattctaa ttaattttct
      841 cataagaaaa atgcttatat cgtgataatg tgaaatgtac ataattataa acaaaaaagg
      901 ggctgtgaca ctaaaaaata gtgctacgcc cttttttatt tgtaataatc atcaatacaa
      961 attattttat tatatgtaat tatttatgtc ttaaccaatt ttatcgaaaa taacagtctt
     1021 ctcttttaaa gagatttttc ctacttgata tccatattca tttaattcct ttttatattt
     1081 caaaaacgaa tggtctatct ctatcccagc aatatctttt atttcttcaa aagttaattt
     1141 aaacgattga ctattgtttt tcttaacata ttcccataaa gaactatatt tactcatctt
     1201 atatcactcc ttttaaaatc atatcttatc tattaattta tattctatca ttattaatgt
     1261 ataaagtcat gctacttatt atttatatat aaaaatatcc aaataataag tagcaatttt
     1321 ttatagtcat aatatttttt tcagattaaa taaaaatcaa ttatagttaa aatattttta
     1381 aaagaaatct atcccattat aaagtaaatt ttaattatct tatttctagt atgtaattat
     1441 tcaaaatagt atatcattat tgaaatacac atctaataac taaaaatttt tacatattca
     1501 ttatttaaaa atctttttat tgcatttaaa ttaaatctat caatatttca gtaataacgt
     1561 tttcttaatt ttcactatgg atgtcgattc aattataatt aaagctctac atcaatcttt
     1621 ttaccactca ttgaacaaca actaactttt gccttatcaa tagagaatat ttcaaactta
     1681 ccatctccta cagagtacat ctgacctaaa cttggcatta tttcaagtgc cttagcttgt
     1741 gtttcttttg atgtaacaaa tactgcttca cctaaaatac gtagagtatt aaggttttgg
     1801 tctatacaac aaagttcaac ctttggatta aaaataagtt gcttaaacat atccttttga
     1861 ttagatgtgc aaaatgtaag tttaccattg tattccataa caaatcctaa aggacgcaca
     1921 tgtgcttgat tgttctcatc aactgttgct aaataataaa ctcctgcctt gttcaaaaat
     1981 tctaatgctt tcataattct tacacccctt ttaaatactt gtattaagga ttatcctttg
     2041 atataatttt aatataaaat acagaaaaaa caagtatgca gttttttctg ataaagtata
     2101 aaaaagatac tactataact aaggagtaat taaaatgagt ataaatactg aaaaaaatat
     2161 aactaaaaac gttgaagaat taacctgtcc aatccgttat gcattagaca ttgtcggtgg
     2221 taagtggaaa ttacctatta tatgtatgtt agcagttgaa aatccaatta gatatagtag
     2281 cataaaaaga aaattggatg gcattacaaa tactatgcta gctcaatcat taaaagattt
     2341 agagtctact ggtattgttc atcgtaaaca atataatgaa attcctccaa aagttgaata
     2401 tacattaaca agtaaaggta aaagtattgt gcctatttta caacaatttg ctaattgggg
     2461 tgctactaat atgcaagaaa aaaacacatg tggacttagt tgcaaagaat gtagaaagat
     2521 aaagtaaatt tactaaatta ttcatattat agactatata ttaatttatc tgattgaata
     2581 taaaaacagg atgacttata tattcatcct gttctatatg ttaagctcta aatttaatta
     2641 gttcaagcat atcgtttaat accaataaac tatctacttg aatcattagc catttacttc
     2701 cattaaaaaa gtttacctca ttatatattt ttttgatata atcacaacaa gtattaataa
     2761 ataaatcaac ctctactcta ttgctttcac ttacaataac caaagcttta aaataacctt
     2821 cttgtggata taaagtacat agtgatttac ctcttttttt atattttaca ttccaacctc
     2881 tttgcattga acatttactg tattcaagct taggttctac attataagta gaaaccaaag
     2941 ttttatttaa cttgtcccat aatggattat taataaattc attaatttgc tcaaatgtag
     3001 gtttagtatc ttgaaaaaac gcatcttgcc aattcatatt catcatcctt tctattgttc
     3061 aataggaacc ggaacaatcc aatgttccag atatgctgct tcaggtgtag tggggtaata
     3121 catctcaatt gcaaaatcag tagttgttaa attatgtttc ttcatccatc tttccataaa
     3181 tttatctgct ttaaaaacag ctgaattaac taactcatta aagttttctg cctcaaatcc
     3241 acatactaaa tattctttag ctggcaactc aaaagtacta tatccttcta ctgatgtacc
     3301 tgactctacc tctacacctg ccatatacat acaatttcct tcttttgcat ttcccatata
     3361 aagagcagca aattcatttc cacctggaat ttgatttggt atattatgtc tttgacttcc
     3421 aagtttcatc cataattcct ctactattgc aattccagtt gtttcaccgc ccaccaactg
     3481 gcaaataggt acttctattt ctattccaac aaatgtcctt ggattactca atgtcttacg
     3541 attgacttca atcactatat catctgcaat cagtggaaca ccttcatcaa ccatagcata
     3601 atttaaaatt aattctggct taataaagtg attgagtttt actggatttg ctctatattt
     3661 ttctggagtt aatccatatg cttttttaaa ggaacgtgta aatgtctcat gactagcaaa
     3721 tccaaaattt aaagctacat caagtatacg attcttatgt tctgctaagt attcagaagc
     3781 tcttgcaaga cgacgaagct ttatatactc cattacagtc ttatttacca atcttttaaa
     3841 tagtctttga tagtaaaatg gtgataaatt tgctttattt gctaattcat taattgatat
     3901 ttcttctgat aaatttgctt ctattaaatc caatgtaatt tgaatagact cccatgcatg
     3961 catactataa ctcctcctga tatttttgtt actcttatcc tttatagtat caaaactaga
     4021 aaaaatgttc ttgatagata gtgccctttt taattttctt atatgatagt gctaaatctc
     4081 attgctttat tataaacata aaatatataa aaataaaata tagcaaatct ttaggtaaga
     4141 tttgctatat tatatatttt attaaactat ttttaaatac tccatttatt tccttaagaa
     4201 agaactcttt catatcatct aattgttctt tatcatacac gtacttacca tatccaaatt
     4261 gaccgtattt aaactttcta tcttcatttt ccattggcaa tagtgtatct ggataaatct
     4321 ctagtattct attttttgct ttagttgtat atctatgaga tataacttca aatataattt
     4381 ttttatcaaa atcctttggt aaagcttctt ttatacttat aatcagattt ttatactctt
     4441 ctttccaacc ttcatataaa aacacaggtg ctattatgaa accaatctga taaccagccc
     4501 tagcaagttt tacagctgac tctattcttt tatttgcaga ggctgtataa tgctcatgtt
     4561 catttataat tctaggagta ttgatactaa atcgtatttc tgtatgatta ttatgttcag
     4621 catccaataa gctatccaca tcactgtatt tagtaacaaa tctaaatctt cctttttcct
     4681 ctcttccaaa aaactctatt gttttcttta aagaattagt atatggctct actggaactg
     4741 ggtctgatgt agctgcccct tcaaatatgg ttacctgtgg ctttctatct tcaatatatt
     4801 tttttgtctg ttcaagtatt tcatctacat ttacaaacac ccttataaat ggtttatcac
     4861 ctaattgtgt gttcaaataa caatactcac atcttcccat acatccactg acaagtggta
     4921 gttgataatt agcagaaggt ttacatgttt gaaacttcag actttttcta atcccaacta
     4981 ccatagtctg cttcccactt ctatattgtt catatagatt ttcacctgga atatgttctt
     5041 taatcctatt tgatgatata ttaattatct ctacatcttt attatctcta aatttattgt
     5101 atattttttt acccacatca gtgtctaaag ttcctttttc gaatattatt cttttgggat
     5161 taaacattta tttcacctct acttaaagtt tttaaatcga agaattttat aaaatattac
     5221 ttaattaatc ttcccttttt taaactcctt tatttattag aaagtaaaat aaaagcttaa
     5281 gacaaattta ttatatatat aacttctata cacaattttt
//
LOCUS       DAEPXW010000170         5089 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.174, whole genome shotgun sequence.
ACCESSION   DAEPXW010000170 DAEPXW010000000
VERSION     DAEPXW010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5089
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.174"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            383..1174
                     /locus_tag="KRM55_003545"
     CDS             383..1174
                     /locus_tag="KRM55_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBH1595730.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            1203..2423
                     /locus_tag="KRM55_003546"
     CDS             1203..2423
                     /locus_tag="KRM55_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBH1595731.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            2443..3138
                     /gene="pxpB"
                     /locus_tag="KRM55_003547"
     CDS             2443..3138
                     /gene="pxpB"
                     /locus_tag="KRM55_003547"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBH1595732.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            3168..4154
                     /locus_tag="KRM55_003548"
     CDS             3168..4154
                     /locus_tag="KRM55_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBH1595733.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(4373..4939)
                     /locus_tag="KRM55_003549"
     CDS             complement(4373..4939)
                     /locus_tag="KRM55_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595734.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
BASE COUNT         1953 a          581 c          929 g         1626 t
ORIGIN      
        1 cttacaaaga atgataatta tatagatgaa agaaacaaat gaatgaagaa aaatgattct
       61 gtcttgcata taaagtgatt aaaaatgaaa aatactttaa aaataaaggt taaagccctt
      121 attttaagtg aaaataatta attattaact aaaaaatggt aaaaagattt tttgaaaaag
      181 aaatacaaat gaatgttcaa ttaaaataat tgcaaaaata ttccttaaat ggtaaaatta
      241 tattaattaa atgcaataga atagttgcaa aaataaaatt gaatacaagt gataaaatat
      301 ttcatgcaat atataaaata aacaaaattt aaaaattaaa actacttatt ctatcaaaat
      361 gttagcaagg aggggtcata aattgtataa agtagattta aatagtgatt taggagaaag
      421 ttttggaacg tataagattg gtttagatga agaagtttta aaatatattt catcagctaa
      481 tatagcttgt gggtttcatg caggtgaccc tagtcatatg gaaaaaacag tacagctagc
      541 taaaaaaaat ggagtgaaaa taggcgcaca tccaggtttt ctagatttaa taggatttgg
      601 aagacgtgag atgaaaataa caaagcagga agctaaagat tatacaaaat atcaattggg
      661 tgctttaatg gcatttgcaa gttcaaatgg atgtaatata caacatgtaa aaccacatgg
      721 agcattatac aatatggcag ctaaagataa agagttagct atggggattt gtgaagctat
      781 atatgaagtc gataaagata ttatactgtt ggggctatat aatagtgaaa tgataaattc
      841 tgctaaagaa attggactta ggtttgcaaa tgaagtattt gcagatagag cttatgataa
      901 taatggtttt ttggttccaa gaaatgtaga aggagcagtt atacatgata caaaacatgc
      961 aatagatagg gttgttagga tggtaaaaga aggaactgta gaaactttaa caggtgaagt
     1021 tatacatatc aaagcagatt ctatatgtgt acatggggac aatccaaaag caatagagtt
     1081 tgtcaaagaa ataagaaagc gttttgaatt agaaagtata gaagtttgtc cattagaaaa
     1141 catagaagtt tgttcgtcag agaacatagt ataagactga taacatgagg gggagataaa
     1201 atatgagtac aaaaaatatt acagataaaa ctaaaaataa aaaagatgtc ggagcactta
     1261 taggggctgc atttataatg gcaacatcag caattggacc agggttttta actcagactg
     1321 cacaatttac ccaagatttt ggaccgaatt tttcatttgt aattttaatt acaacaatcc
     1381 tttttatagg ggctcaagta aatgtatgga gagtaattgg tgtatcagga cttagaggtc
     1441 aggatatagc aaataaaata ataccaggat taggttattt agtagctttt ttagtagctc
     1501 ttggaggatt agcttttaat ataggaaatg ttggtggagc tgcacttggt atgaatgtaa
     1561 tgtttaatat gaatatgaca ttaggaactg tattaagtgg attaatagcc atatttgtat
     1621 ttatgtcaaa aaattcaaat tctctagtcg ataagataac taaattttta gcattaggaa
     1681 tgataattat agttggatat gtagcaatat caaatcatcc tcctgttgga gaggcagtat
     1741 caagaatggt aaaaccagaa aatccaaaag gactgatatt cccaataata actctacttg
     1801 gaggaagtgt tggaggttat ataacttttg ctggaggaca tagattaata gacggtggaa
     1861 taacaggaga agaaaatata aaagaaataa ctaaatcttc tcttttgggt atattagttg
     1921 ccacaatgat gagagttctt ttatttttag caatactggc agtggtttca aaaggtcttc
     1981 aacttgaccc agaaaatcca gctgcttcag cttttaaatt tagtgcagga gcaataggat
     2041 ataaattctt tggacttgta ttatggtctg ctgcaattac atcagttata ggagctgctt
     2101 atacatcagt ttctttctta aagacactaa atccttttat agataaatat gaaaaatatt
     2161 ttataatagc atttatagca atatcaacac ttataatggc atttatagga aaaccagcta
     2221 ctttattaat tttagcagga gctttaaatg gattgatact tccaatcaca ttaggaatta
     2281 tgcttatagc atctaaaaga aaagatattg ttggagatta caagcatcct acatggcttt
     2341 taatatttgg attaatagta gttttaatat ctgcatatac aggaataact tctcttagca
     2401 gcctaggtgc tttatttgct taatttagaa gaggtgacat ttatggaaac tagatacttg
     2461 atatcagggg ataaggcagt ggttgctgaa tttggaaatg agatatcaga agatataaac
     2521 aaaaaagtaa tttcatttat gagagcaata gaaatatcga atcttaaagg tattgtaaca
     2581 gaaatggtac caacatatag gtcacttatg ataagttata atccattaga aatagatttt
     2641 gatagtttga ttgagaattt aaaaaaaata gaagataatt tggaaagtat agtattacca
     2701 aaacctaaaa tacatgagat tccagtatgt tatgatgagg tttttggtat agatattaaa
     2761 aacgttgcaa gctacaataa tctcactgta gatgaagtta taaaaataca cacaagcaga
     2821 gagtacttga tatatatgct aggttttact cctggatttc catatctagg tggtatggat
     2881 gaaagaatag ctacacctag attagaagtg ccaaggacta aaatttatgg tgggagtgtt
     2941 ggaatagcag gttcccagac tggtgtatat cctattgata gtcctggtgg atggcaaata
     3001 attggtagga cacctttaaa attatatgat gaaaatagag aagaacagat tttgcttaga
     3061 gctggagatt ttataaaatt tgttccaata acattagatg aatttataga aatcgaaaaa
     3121 aataacttaa gtatttaaat atcgttatag tacagggagt ggtatatatg ggattcaaag
     3181 ttgaattagg aggtttccaa acattaatac aagacagagg tagagttggc tatggtcaat
     3241 atggtgtatc tggatgtgga gcaatggatg agtatgcaca tagagtagga aatatattag
     3301 taggaaattc tgaagatgag gcttctttag aagttttaat gttaggtcct acaattacct
     3361 ttgatgaata tacgcaaata gcagtaactg ggggagattt aggggctaaa ataaatggaa
     3421 aagaaattca aaactggagg tcatatcaaa taaatccagg tgatgtatta tcatttagag
     3481 gtgtgaaatc aggtgctaga gcctatgtgt caatagctgg tggaatagat gttccacttg
     3541 caatgggaag taagtcaact tatacaagag ctaaaattgg tggatttgaa ggtagagcac
     3601 ttaaaaaagg agattatata aatactttta ttcaggaaaa agattttaca ataaataaaa
     3661 aattaagttc aaaatatatt ccaacttata gttcagaaat cgtactaaga attgtaaaag
     3721 gtcctcaatt tgatgctttt tctaacggtg aagtagagaa atttttatca aataaataca
     3781 aagttacgaa tgaaatagat agaatgggtt gtagactaga tggagagagt ataaagcacc
     3841 ttaatggagc agatattata tctgatggta tttcttatgg agctatacaa gtacctggtc
     3901 atggaaaacc gattataatg ttatcagata gacagactag tggtggctat actaagatag
     3961 ggaacgttat aagtgtagat ttgtataagt tagcacaagc aaagccaaat gatgtagtaa
     4021 aatttgaact tgtagatata tatgaagcac atagactatt gagagagcaa gaagataaga
     4081 ttcaagatat ctacaagagt atgaaaaata taagagttgt aaaggcaaaa gtattaaatg
     4141 atatagcagt ttaatttaat tttaacaaat acaattttta ttataattta taatataact
     4201 tacaaatagc tatttactat ttaccataat taagatggtt tagattagtc aaatagctat
     4261 ttttttagtt tgagtaaata ttttaaattt aaataaatac ttcaaattta aaataaaagc
     4321 aatatttaaa tctattatat tatctacaaa aagtaggtat gttatattga gtttatttag
     4381 attttattgg ccaaattgga ggtgatataa ctccatatcc acgagctatt gtatctttac
     4441 ttggattgat gattttatgt ggtacattag cttttataaa tgttgagtca cctggattta
     4501 atctaactac cttttcaccc atacaaatat caaccacacc actcgttacc accataattt
     4561 cttctgatgc atgatatata taatctttgg catcctcact ttctggttta agttcaaact
     4621 ctacaaataa aattgaaggt gtaaactcag ttgtaggcat tggagatact atctcgtaaa
     4681 acatttcact ctttggaaat ttcatcataa ctctatcttc ttttctaatg actaaatcat
     4741 cagtattatt gtcatccata aacatatata aaggagtgtc taaaacttca gcgatttttc
     4801 tcaatgaaga caaggatggt tcaatagcat ctctttctat ttgagagata taacttatag
     4861 ataaatctgt caatttggaa acatcactta atgttttttt cttgcttttt cttatatttc
     4921 tcatcttttc acctagcata agaacctcca aataataaaa ttaatataaa atattcgctt
     4981 aaaacaaagt aattatagca caacatagaa gtagtggcaa taagaataca tagtagattt
     5041 tgacaattaa aatttaatta aatccaaata aaagtctatg aaaatgaat
//
LOCUS       DAEPXW010000171         5034 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.175, whole genome shotgun sequence.
ACCESSION   DAEPXW010000171 DAEPXW010000000
VERSION     DAEPXW010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5034
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.175"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            119..1186
                     /locus_tag="KRM55_003550"
     CDS             119..1186
                     /locus_tag="KRM55_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBH1595735.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            1205..2365
                     /locus_tag="KRM55_003551"
     CDS             1205..2365
                     /locus_tag="KRM55_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH1595736.1"
                     /translation="MNTLFSNSGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            2378..4474
                     /locus_tag="KRM55_003552"
     CDS             2378..4474
                     /locus_tag="KRM55_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBH1595737.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSAKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTVITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(4633..4977)
                     /locus_tag="KRM55_003553"
     CDS             complement(4633..4977)
                     /locus_tag="KRM55_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH1595738.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
BASE COUNT         1919 a          577 c          930 g         1608 t
ORIGIN      
        1 tttggaaaag agtaaatttt cagtaaatta tcttgacata tatattgaag taataatata
       61 atttaaagta taaaatttta aaaattgaat tataacttca aaaaataagg agggtaatat
      121 gaagataaca gatatcaaat ttgaaaagct tagaattaaa ttaaaaaaac ctgtagtagt
      181 ttcatttgga gtaattgagt atggagaaag tataatttta aaaattgaaa ctgatgaagg
      241 gtattgtgga tttggcgaag cagcacctct tgcagcagtt acaggtgaag ttttggataa
      301 tgttctttca gtattgctta tgtttaaaaa agagttaata ggcaaagacc cactagatat
      361 tgaaaccata cataccatca tggatggaat tattataggt aatacttctg caaaagcagc
      421 tattgacata gctttatatg atattaaagg aaaaattatg aatgcacctc tttataaagt
      481 tcttggagga tttgatagta aagtccaaac ggatattact ataagtatag ataagccaga
      541 aaaaatggca gtagaagctt tagaaagagt aaaagaaggt tttaggatat tgaagcttaa
      601 agcaggtata aatcctgaag acgatattga agctgtaaag ttaattagag aagccgttgg
      661 agagagtata agaattagaa ttgatgcaaa ccaaggatgg aacgtaaata gcagtataaa
      721 tactatcaaa aagttagaag aatttaatgt tgatgcaatt gaacaagcac ttccacattg
      781 ggatttagat ggtactgctt acataagaaa taaaagtaac acaaaaatta tgatagatga
      841 atcattacat tcaccaatag atgcaattaa ggctataaaa aagaatgcag ttgatacatt
      901 taatattaag ctgatgaaat caagtggaat atatcctgct ataaaaatca acaacatagc
      961 tgaggcaagt ggagtaaatt gtatgttagg atgtatgctg gaaacgagaa ttggtataac
     1021 agcagcagca aatttaatag catctaaaaa gaacataaca gaagctgacc ttgatagttt
     1081 tatgttttgt gaagaattag aaggtatatc tggaggattt gtaatggatg gagatattat
     1141 gaatcttgtc aataaaccag gtttaggaat agaagtaaac ttatgataaa tttggaggtt
     1201 aaatatgaat acactttttt caaattcagg tagtatactt gctgtaatga catcaatgat
     1261 tgcattgggt ttttacttac aaagatacaa agccattaaa agcttaggac cagcacttac
     1321 aataatcata atgggaataa tactttcaaa cttaaaagta gttccagtaa gtactgagtt
     1381 atatggaact atttcaacat atgctattcc agtttctatg actataatgt tgatgagtgt
     1441 tgacttaaaa gaaatgacaa aattatcaag agaaccttta attgcaattt ttgtagctgt
     1501 attaactgta agtatcatgg catttttatt tggattagta tttgcagaaa aaatatcaga
     1561 aggttggaag gttgctggaa tgtttgtagg tacatacact ggtggaagtg ctaatcttac
     1621 agctattgga acaggtctta atgtaagtag acaaactctt gcagcagcaa atgcagcaga
     1681 ctatgtaatt ggagtaccaa cattgatatt tatgtttgct ctaccagcaa tattaaaaaa
     1741 ttcaaagaag tttaaaaaac tttggccata tcatgtagaa gaatcagaac tagaagattg
     1801 tcaaaatgaa gaatttatgg agtcaaaaga atggagtatt aaagatatag cttggatgtt
     1861 ggctataggt tttgttgtta cagaggtttc aacaatactt gctggatatt tcaattcaag
     1921 ttttagtagt gcagcaagaa tacttttagt tacaacaatt tcaattataa ttgctcaatt
     1981 aaagccagta aagaaactaa agggaaattt agatttagga ttatttgttg cattattctt
     2041 tttatgtaca ataggttttt cagtagatat aaaagagttt ttaggttcaa cttttactat
     2101 aacactttac tgttttagca taatttttgc ttcatttgtt ttccatttag gcataactag
     2161 acttttaaag ataaagtatc aatatgtaat actttctata gtaggagcaa ttgctgatgg
     2221 tcctacttca gctttagtag ctgcttctgc aaagtggaat tcgcttgtaa gtgtagcagt
     2281 cgtaatggga gtaattggtg gagtattagg aaattatgca ggtatatcag tggcatatgc
     2341 aataaagatg tctctaggat tatagggggg agtttaattg ataaaattta aattatacat
     2401 atctggacta tacagtggaa atgtaatctt tgatggagat ttattaattg aaaagttgaa
     2461 tccttttaca aataaaatag aaagtttaaa accaataagc aaagaagaaa atacatatta
     2521 tttaaatctt acaaaaatag atttaaagtc tttatttaat aattttgatg tatatactaa
     2581 aagcttagta aacacagata aagacacagt tataaataac ttaggagaaa cgcattctaa
     2641 acttaatgaa tatatatggg ttcaaagaaa caaaaagttc ccactagata taattattgt
     2701 agataataaa atagtaggtt ttatctgttt atctagagaa acttgtacta tattaattat
     2761 ggatggatat gaagagtata ctgtattaaa agaatgggaa aaaactcata aaaatgaaga
     2821 gatatattct ataagatttg gtggaaatta tatgattgat atgaaagatg gtataaaact
     2881 ttctacagat gtatatctcc ctgattttgt agattctgcc aaaaaagcac cgacaattct
     2941 tatgagaact ccatatggaa aagaaaatga taaagaaata tattataaat atgtacaaag
     3001 aggatatgct gttgtaatac aagatgttag gggaagaaat gaatcagaag gtaagtggga
     3061 acctatgatt catgagaggg aagatggaga tagtaccata aattggatag tatcacagga
     3121 atggtcaagt ggaatagttg gaatgcttgg agcatcatat cttggttatg tccaatgggc
     3181 agctgcatct tcaggcaata agcatcttaa agctttagtt agtatagtaa catcaggaag
     3241 cccttttatt gatataccaa gaaaaggagg agcttttgta tctggtatgc ttgcatgggc
     3301 atttatggta tcaagaaata aagttgatag aagcaaaatg gtaagagatg attgggatga
     3361 tgttttaaac atacgaccaa tagaaaatat acctgttgaa gctcttggat atagaattga
     3421 atttctggaa gaatggttaa agagagtaga aaaagatgag tattgggatt tgatggattg
     3481 gcatttacaa aaagataaaa taaatgtacc tgcattggtt gtatctgggt ggtatgatga
     3541 taatagtatg ggaactacag aggccttaga tgttataaag gactatgaaa aaggaaagag
     3601 aaaggctatt ctaggtccat ggatgcataa ttcaaatact ttaagagata taaatggtat
     3661 ttctttagga aatagttcat taagatatga tttggattat aattatctat tatggtttga
     3721 taaatactta aaaggtatag aaaataacat agatacgact gctccagtag agtattactc
     3781 tgtaggttct aataagtgga agacagaaga aaattggcca ataataaata agatagataa
     3841 aagtatgtat ctaataagtg atggaaatgc taacacatct ttaggaaatg gtagattagt
     3901 atttgataat gatttagaag aaaagtatga tagttatata tataatccaa aagacccatc
     3961 agtacaacta attgatatgt cagagaatga agttggagtt ccaaataact acaaagattt
     4021 agaaaaaaga agtgatatgt tgtgttatac atcagatgct tttagtgaag aatttactgt
     4081 aacaggtgat ataaagttag agttttttgc atcaagttct gccaaagata ctgactgggt
     4141 tataaaaatt atggacgtgg atttagatgg aaattcaatt aaattagctg atggtatact
     4201 tagtgctaga tttagaaata gtttttataa gtcagagttt atggaagaag gagagattta
     4261 taagtttacg gttataactt caaaaatatc aaacacgttt aaagttggtc ataaaattag
     4321 actagatata acatctagtg ctaaaaactt tattttccaa aatagcaaca cgacagaggg
     4381 atataatagt attgaatata tagaagcaaa gaatacgatt taccatggag gtaaatatcc
     4441 atctaaattg atattgccaa tagagaataa gtaaatttat atagattaaa tagtgaggag
     4501 gtgtctcaaa atgaattttt tagttcgtga gacactttct tttatacgaa atcaaatata
     4561 ttttcatcat ttcaacaatg aaaaaaaggc ttatctctct gttttgagat agcctcctat
     4621 aagctaaatt gattattttg tagctgcaac aacgctcatt tcaactaaca aatgctctct
     4681 agcaagtcta gcttcaacac aagctctagc aggttcaaac cctttttcaa cccaagcatc
     4741 ccaaacagag ttcatagctt caaagtcttt catatctctt aaataaatag taacagatag
     4801 caaatgttgc ttatctgaac catatttgtt taataaatct tctattttag ctaaaacttc
     4861 agttgtttgt tcaattactc ctccttcagc atgagtttgt ccacataaat aaactgtatt
     4921 gttatgaact acagctctac tcattcttcc agttccttca tatctcttta tttccatatt
     4981 ttaaatacct ccatagttaa aaaatctatt aaaaatctaa ataataaatt aaaa
//
LOCUS       DAEPXW010000172         4964 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.176, whole genome shotgun sequence.
ACCESSION   DAEPXW010000172 DAEPXW010000000
VERSION     DAEPXW010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4964
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.176"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(296..2128)
                     /locus_tag="KRM55_003554"
     CDS             complement(296..2128)
                     /locus_tag="KRM55_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595739.1"
                     /translation="MSRIGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            complement(2121..4367)
                     /locus_tag="KRM55_003555"
     CDS             complement(2121..4367)
                     /locus_tag="KRM55_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595740.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            complement(4435..4896)
                     /locus_tag="KRM55_003556"
     CDS             complement(4435..4896)
                     /locus_tag="KRM55_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1595741.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
BASE COUNT         1561 a          928 c          563 g         1912 t
ORIGIN      
        1 ttaaaattaa attctattta taataaaatt taaagaataa aattaaatat acattttgat
       61 aatcacctcc aacattttcc ttactacata ttataataaa ataaacactt tgtaaagaca
      121 taaaattatg tggctatctc aaaatataga gaatcctctt tttcattgtt aaaatgataa
      181 aaatacattt tatttcatac acaaaagagt gccttatgaa ttaaaaagtt cattttaagg
      241 caccctcatt tattttatct tattaattac atgtctatgc taagatagtt ttttgttaca
      301 ttgcttcatc ttcttcaaat tgagaattgt aaagattggc atagaatccg cctttcttta
      361 gaagttcctc atgatttcct tgttcaacta tatctccttc attcattaca agaatcatat
      421 cagcatcacg tatagttgat aatctgtggg ctataacaaa acttgttcta ccttccataa
      481 gattatccat agctttttga atcaatactt ctgttctagt atcgacagaa cttgtagctt
      541 catctaatat taaaatttta ggatcagcta aaatagcacg agctatagtc aataattgtt
      601 tttgaccttg agaaacatta cttgcttctt catttaattt catcttatat ccatctggta
      661 atgtcttaat aaatctatga acatgtgcag atttagcagc ctctataact tcttcatctg
      721 tagcattcaa cttaccatat cttatatttt ccataattga accactaaat aaccatgtat
      781 cttgaagaac cataccaaac atttctctaa gctcactacg attaaaatct ttaatattat
      841 gaccatcaat cagtattgaa ccgctattaa catcataaaa tctcattaac agtttaacta
      901 ttgtagtttt acctgctcct gtaggtccaa caatagcaac tttttgacca ggtttaacat
      961 ttactgagaa atcatttatt atagtcttgt ttgggttata tccaaagttg acattttcaa
     1021 aatcaatttt accttctaaa ccatctattg aaactgcatt ttcaacaatt tggacttctt
     1081 cttcctcttc taaaaactca aatactcttt cagaagctgc tgctgttgat tgcaataaat
     1141 tggcaacctg tgcaatctga gtcattggct gtgtaaagtt tcttacatat tgtataaatg
     1201 actgtatgtc tccaacctca attgttttct taattgcaag ccaacctcct aagattgata
     1261 ccattacata tcccaagttt ccaataaaca tcataagtgg ttgcattata cctgataaaa
     1321 attgagattt ccacgctgaa ttatacaggc tatcatttag tttatcaaac tcttcaatta
     1381 cttcatcctc acgattaaat gcttttacta ttgtttggcc actgtaagtt tcctcaactt
     1441 gaccatttac atttcctaaa tattcttgtt gatatctaaa gtatttttgt gatttcttta
     1501 ttattcttga aattacaaac attgatattg gtaatattaa aactgccact aatgtcataa
     1561 ttccacttat agataacatc attatcaaaa cacctatcat agttgttact gatgttataa
     1621 gctgtgtcat actttgattt aaactttgat ttaaagtatc tatatcattc gtaattctcg
     1681 ataatatttc accatgcgtc ttagtatcaa aatacttcat tggtaatcta tccaattttg
     1741 ctgaaatctc ttttcttaaa ttataggata ctttttgaga aattccactc attataaatc
     1801 cttgtataaa agagaacagt gcacttatca aataaaggaa aagtaaaaag gttaagattt
     1861 ttccaattgc attaaaatct atacctacgt ttcctccaga aactttactc actagccctt
     1921 caaatatctt tgtagttgcc tttcctaaaa tttttggacc tactatagaa aacgacgcac
     1981 taccaatagc aaatacaatt actaaaatta ttgatatttt aaatttagat aaatatgcaa
     2041 ttagttttcg catagtccct ttaaagtcat ttgctttttg tcctgctccc atagattttc
     2101 ccataggacc tcttccaatt ctactcatta gctagctcct cctttgaaag ttgtgataaa
     2161 gctatttgct cataaacttc gcaatttttt agaagctctt tatgtgttcc tattccaact
     2221 atttcgccct catttaaaac aattatctgt tctgcattta agatagtact aattctttgt
     2281 gcaactatta gaactgtact ttcagcagtt tttgatttta aagccttacg aagagctgca
     2341 tcagttttta agtcaagtgc tgaaaaacta tcatcaaata tataaacttc tggatttttt
     2401 gctattgctc ttgcaataga aagtctttgt ttttgacctc cagatacatt tgttccacct
     2461 tgagaaattt cagttttaaa agcttccggt ttagaatcta taaattctgt agcttgagct
     2521 atttcagctg ctgttctcat ttcttcatct gttgcgtctt ttctaccata ttttaagttg
     2581 gattctatag taccagaaaa caatactccc ttttgaggta catatccaat tttttccctt
     2641 aaatcatgtt gagaaacatt ttttatatta actccaccaa gtaatatttc tccttcagta
     2701 acatcaaaga aacgaggaat taaatttata agagttgact taccactacc agtacttcct
     2761 ataaaggcag ttgtttctcc tggctttgct gtaaaagata tatttgttaa tataggttct
     2821 tctgcgtctg gatacatgaa cgaaacattt ttaaattcaa caagaccctt tttatcttcc
     2881 ttaaactctt gtgcctctga tttttctggg tcttttatgc ttatatctga cactaatact
     2941 tcatctatac gtgtagctga aacggatgct cttggaagca taatagatac cattgatatc
     3001 attaagaatg acattattat ttgcattgta tattgtataa atgccatcat atctccaact
     3061 tgcattgctc cagaatcaac actgtatgca cctctccaaa ctataagaac tgtgataagg
     3121 ttcattataa gcatcatagc aggcatcata catgtcataa ctctatttac aaaaagattt
     3181 gttttagtta aatttttatt tgctttatca aatctttctt cttcatgttt ttcagtacta
     3241 aaagctctga taactggaat accagtaatt atttcacggc ttactaagtt taacttatca
     3301 acaagctttt gaaccagttt aaacttaggc ataaccactg agaataacac tacaattaat
     3361 gataagatag caactactgc tactgctata atccaggcca ttgaagtatt tgtgtttaaa
     3421 acctttatca ctccacctat agccattata ggtgcataga atactattct aagcaacata
     3481 accatcaaca tttgtatctg ttgaatatca tttgtactac gagtaattaa tgaagctgta
     3541 gaaaattcat tcatttcagt atttgaaaat gacataactt ttctaaatac tccacttctt
     3601 aaatttctac ctacacttgc ggctactctt gctgctaaaa atcctactgt tattgtagct
     3661 accatactaa tcattgctat accaagcatt ttagcaccag taaataatat ataattattt
     3721 tgagtttttt ctgtatcaat acctattttc tcatattctg accttacata tgaaacagag
     3781 ctttgtgtta tcatactctc tggcatactt tcaaagcctt tgctcatctc tttagtcaat
     3841 gtatctaact gttcctttgg cattgctgat aacaatttaa atatatcaac atctccactt
     3901 tgagtagctt gtggtggaag tttactcatt aactgagctt tcatagcttt tacctcttta
     3961 ctatcgccct caagccctga tactattaaa atagctttac caaaaataac atttaaatca
     4021 tctatagtgt ctttgtcttt agtatttaac tcataaagag attcatcttt tagacctggg
     4081 tacttatctt tatacttaac ataatccttt ttattcagca aagtataatt atctagtact
     4141 ttatccttac tacttttatc cataaataaa gtaattttat ttaattcact ctctctaatc
     4201 acagatggaa cagagttttc tactccacct tgttgtatac ctacatttac tatattggat
     4261 gtgtattctg gtaaagaaag gtcacatacc gcttgaatta ccaatagaca gactattatt
     4321 actattgata atgccgattt ctttaaatat ttaattaatt taaacataca tttcttccct
     4381 tctgtaatat taattagtct aataacatta aattgaaaaa cattatttta aactttaaaa
     4441 atatttttca tcttcatgct tatgacatcc tgcttttaaa ttatctcgta cttgcattag
     4501 aagtcttcta agtactattt tttcttcttc actaaatcct aaaaaaaact ctctttccaa
     4561 ttccttgtta aattcttcaa ctttattaca tatttctaaa cctttgtctg tcaaaaaaat
     4621 cctagatact ctttggtcct tttcatcttg ttttctttcc acaagtccag ctttttccat
     4681 cctctttatc ataactgtag ttgtagatgc ttttactttc cttttatctg ctaattcttt
     4741 ttgactttgc ccatctttca tctttaaaga aaaaagtatt tggggttgac catgatataa
     4801 gcctaattta tcaaaataaa aatgagttct tataaaatat attcgcatta attgcaagaa
     4861 aacatcattt aatttttctt cagaattgct attcatactt gccctcctta ttttttatat
     4921 tacttagtcg gctaagcatt attttactat actgcatgca tttt
//
LOCUS       DAEPXW010000173         4934 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.177, whole genome shotgun sequence.
ACCESSION   DAEPXW010000173 DAEPXW010000000
VERSION     DAEPXW010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4934
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.177"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(558..1199)
                     /locus_tag="KRM55_003557"
     CDS             complement(558..1199)
                     /locus_tag="KRM55_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBH1595742.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQVSDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            complement(1442..2245)
                     /locus_tag="KRM55_003558"
     CDS             complement(1442..2245)
                     /locus_tag="KRM55_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1595743.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGRESIAKVYVTCTKHPDGVEMARDVHQSMKDLIASFAQDPSIIPGASKSNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            complement(2381..3556)
                     /gene="thiI"
                     /locus_tag="KRM55_003559"
     CDS             complement(2381..3556)
                     /gene="thiI"
                     /locus_tag="KRM55_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBH1595744.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            complement(3602..4753)
                     /locus_tag="KRM55_003560"
     CDS             complement(3602..4753)
                     /locus_tag="KRM55_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBH1595745.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENIPGIYGLGEAVRILNKDLDAVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
BASE COUNT         1533 a          935 c          471 g         1995 t
ORIGIN      
        1 agttactatt tattgaaaat ttagatattt ttctaaaaat tatctatgtt aatagttaaa
       61 tttatgaaca ttttttgttt ttatgttagg atatttctta gaaatgaaat acttcttaat
      121 ttgatttgat atgtatattt ttatagctat tttattataa aaaaaaagaa cccttttata
      181 actaagggtt actttttttc tctatttttt cttattatat cactattttt tccctatttc
      241 aatattttga cattttttcc attatactga aaagatatct taaattttta acttggataa
      301 attttaaagc atatacttaa aattaacata cttgttttct attttattac acttaatcct
      361 tatttttatc attctacaaa acaaaaataa aaaagaataa gataataaat aaaatactta
      421 tcaccttatt ctttatttaa ttattttaca acgaaaaatc taaactactt tttaaatagc
      481 ttcctcttcc atcaatttat ttgtatatta ctggtttaat tcttcaagta actgattggt
      541 tcttgcaata ctttatccta aactctggaa actttataaa ctacctctct agcatttggt
      601 aaatttccat ctggaatacc tacagcaata ccaaatggta cagaataccc ttctggtata
      661 tcaagtagtt ctctgtattt tttatttgta tcaaacttca tctttattga ctctgattct
      721 tttacatctt ctttatccaa tacactcaca agaccttcaa tatccccttg ttcaacaggt
      781 gtaaataaac ctctaaccat tcctattata caacttccaa gccctagtgc ttgtgcagct
      841 gttgttatat tccctgtaag tattcctata tcatatggag cccatgaact actttcatca
      901 taagaaataa ataaaacggt tggagcacca taaaataact taaagttttt atttatctca
      961 acattactca cctcatgaat cctagataaa gtatcatcac taatctcttt taaaagtttc
     1021 tggtcttgca caacagttat gtgccaaggc tgtttattac atcctgaagg tgctgcaaat
     1081 gcacagtgta ataatgtgtt tacttgctca tcactaactt gttctgtcgt aaattttcgt
     1141 atacttctac gactttgtat taaatttatt gtttggttgt cttgaaaatt attattcata
     1201 tctattcccc tttttatgta tttcttagta caaatactaa atcttcagaa aattaatctt
     1261 atagttaaat ttctttacaa tattattata attattttta gcttatatgt gaagacttaa
     1321 aaatataaac acttttaata tatctcaatt atatatataa atgaaaatct ggtattcgtc
     1381 atctatagaa actgctcttt tctatagttt aatcaatacc agattaataa aacatgatat
     1441 attaatttaa aggaccccat ccctctttag aatgaatctc tgtttttaca gacttaacac
     1501 tatctgtgtc aacatcccat gacctacctg caacagaaat accattttta cctttatacc
     1561 atctaccttc atcataatcg taaactaggg aagtatacca attacctcca gtcttattat
     1621 ttgcaaatac aactacagta gcatcagatt tagtaggatt atatgcatat ggttgtatat
     1681 atagtgtatc cttacttaat ccatattttg ccttaaattc atctggaatt gtaggccacc
     1741 catttttata tttattgtct aataaatatt ttctaaaatc atcattgctc tttgaagctc
     1801 ctggtattat agaagggtct tgtgcaaatg atgcaatcaa atctttcata ctttgatgta
     1861 catccctagc catttcaaca ccgtctggat gttttgtaca agtaacatac acttttgcaa
     1921 tgctttctct tccagtgatt ccatcataac catcatcaaa cgttgctgaa tatattccac
     1981 ctgacttaca ctttggttct gtttcaaagt acttaccatc tttgttttct aatacctctt
     2041 ttatgacttc attcttgtct ttacttgatt cctcagccat tgcaataaca atttgagtct
     2101 ttatattttc tctattagaa agacatgtaa ctgctttact tttttctata tttctaaata
     2161 acgctggaac agctactata actaaaatgc ctattataga tataactacc aacaattcaa
     2221 ttaatgtaaa acccttttta ttcataataa tcattcccat taaataaaat tatagtactt
     2281 atttttaaat actacatatt aataaattgt ctacataaat cctttcaaca gaactactaa
     2341 tatactcaat attcaattta ataattaaat aactcgtatg ctaaaactca atatcctcta
     2401 cctctatttt gtcaatagca tcctgtacta atttttcaat gtcaagtgct gtttcagatt
     2461 tttctatttt ctctaatcta ggtttagtga cgggctttct aggagaaaat acactacaac
     2521 aatcttcttc aggcactata gatgtttcaa aagtccctat ttttttggct atatcaacta
     2581 tatctgattt atccattgct ataagtggtc taaacactgg taaatctaca acggcattag
     2641 tacaagtaag cccttgtata gtttgagatg caacctgccc aatactttca cctgtaatta
     2701 aagcatcaca atgtcttttt tcagaaagcc tctgcgctat cctcatcata aatcttcttg
     2761 aaagaatagt agcttcttct tcattacaat tctcaccaat tgctttttgt atttctaaga
     2821 tattaacttt atgaagcctt actctaccac agtattttgc cagtatttta gctaaatcct
     2881 taactttttc ctgtgacctt tcacttgtaa atggataact atgaaagtga actgcctcta
     2941 cttccatacc tctttttgca accatccatg tagccactgg gctatctata cctcctgata
     3001 aaagagacat agctctacca ttcgttccaa gtggcaatcc accatatcca ggtatagtat
     3061 cactatagac catagtatga aattctctgt attcgcactt tattttaact tctgggtttc
     3121 ttacatcaac attaatccta tctcctacct ttgataataa gtatccacct atatccatac
     3181 tcatttcttg agaagtcaac ccgaaagact tatctcctct tcttgactct accttaaaag
     3241 ttttataccc agcctctatt ttttcttcta acatttttaa agctatttct tttaatgtat
     3301 cataatcttt tttagctctt actccagggc acacacccac tatcccaaat acttttctaa
     3361 cttcttcaat tacttcttca taatcatagt cttctaaatc aacatatatt cttccatact
     3421 ctttatatac attaaatctt ccaattggtt ttaacatatt tcttatattt cttataagcc
     3481 tattctcaaa tatatatcta ttctttcctt ttactccaat ttctccatac tttactatta
     3541 atatattata caccatttca cctcttaaac taatttatta tcactatcta tacagtattc
     3601 tttattttct tttcattatt gaccttaagt cacaaattga ttctttcaaa actttcacag
     3661 cttctaacat ttcttcttct gtattcatat cagataaact aaatcttatt gttccattta
     3721 tttcttcatt tgtaagacct atagcattta atacgtaact acctttcttt ttagaagaac
     3781 atgcagagcc agttgataca taaatacctt tttgctctaa gtaatgaagt aaaacttctc
     3841 cttttgtccc tctaaatgat acatttaata tatgacatac tccatcttct ggagaattga
     3901 tttttatatc ttctatatta tcaattattt cattttttaa tatatttttt aagttattta
     3961 ctttcgaaat aacagcatct aaatctttgt ttagtattct aacagcttct ccaagaccat
     4021 atattccagg tatattttct gttcccgacc taattccaat ttcctgacca ccacctgtta
     4081 acataggctt aaggcgatta ttttctttta tatacataaa tccaattccc tttggaccat
     4141 gaaatttatg tgcacttaca ctcataaaat ctatattgta tttagatggt ctaaagttaa
     4201 tttttccata tgactgaata gcatcaacat ggaaataaat tttttctttt aaacccttca
     4261 aatactttcc aacttcacct attggctgta tagttcctat ttcattgtta acatgcatca
     4321 tgcttactaa gcatgtagtt gactttatcg cattttttaa atcctctata tttattttcc
     4381 catcttttcc gacctctaaa taagttactt caaaaccatc ttcttctaaa tcttttaatg
     4441 tatttaaaac agaaggatgt tctatgttag tagatattat gtgatttttt ctttttttat
     4501 ttaaactagt aatacctctt attatagtat tattacactc tgtaccacct gatgtaaaat
     4561 aaatctcctt ttctttcgct cctagagatt tagctatatc ttgtcttact tcttttatag
     4621 ctttttcaac ttctacacct tttctatgga cagaagaagg atttccatat tccgtattaa
     4681 gtgcataaac cattttatct ataacttctt gataaggttt tgtagttgcg ctattgtcta
     4741 agtatatttc caacttaatt acacctacct ttatttaaaa tcttcaactc taactattat
     4801 accactaatt atagtatttt ttttgttaat ctttattaaa aagacaatct taaattataa
     4861 aatattattt catgaaaagc tagttttttc actttattac aaatttttat agtaaaatat
     4921 aatatactta tact
//
LOCUS       DAEPXW010000174         4934 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.178, whole genome shotgun sequence.
ACCESSION   DAEPXW010000174 DAEPXW010000000
VERSION     DAEPXW010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4934
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.178"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            685..4827
                     /locus_tag="KRM55_003561"
     CDS             685..4827
                     /locus_tag="KRM55_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HBH1595746.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTNPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDVVVESIPN
                     PNPTNNIANIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWTGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNASTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWT
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATVSSTTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGRRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSFNIGTLDAGEIRNIIIRGTVSQTAIGTIVNTATVSSTTPDPNLNN
                     NTSTSEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPAS
                     ILSPEYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTT
                     PDPNPDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNI
                     AEVTSTTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDF
                     WC"
BASE COUNT         1914 a          719 c          828 g         1473 t
ORIGIN      
        1 tcaaaattat atataaaatt cagaaaaaaa ttttagttta cataataaaa ataaagtcaa
       61 ctaaaattat tgattttaga ttaaagtacc agattaagca tttaagtaga ttttaagctt
      121 gatttgatta gaaaggtaca aactatcacc gaaaaaaatt aaacccattt aaaaagcaat
      181 ataaaagctt gttatttttg agaaaaatag accctctaaa ctcaattaga taaaaataaa
      241 atacagaaaa ttatatctct aaatatctca agtaattaat tttaaatttt acgatatttt
      301 gtttgatgat ttataatata aaagcatact cttaatctgc tcaaattaaa aagaataaaa
      361 aataacaaaa aaatcactga catttcactg acaaattgta attttgttat tataaataca
      421 ttgaaaatac ttgattattg aaaaatggca taaaataata ccttttatgc catttactat
      481 tatttgatag tttttaactt atgacataag atatttttta acatatacaa taaaatataa
      541 aaaaattgat attgcaaata aaaaaaatac atattagatg ttatagaaaa aaagcgcact
      601 tataggctta aaatgtcaca taaaagagtt ttaaagaata atatattatg aacacaaatt
      661 ttgtaatcac aaaggagtga taatatggca acagtatcag gacaaatagt ttttgataga
      721 aatagaagtg ctaccattga ttctggagac tcaggaatag ccaatatacc agttgtatta
      781 caagatatag caactggagt tagacttgtg gttctcacag atgcatcagg aaattatgtt
      841 tttactaatg ttccaaatgg taactataga attgtagaag cttttggaac tacaggagga
      901 gtaccaacac cagggaattt tgcaacagcg atagtaggtc cagttccaat tgcagaaatg
      961 ccacctatta gttctgtgac aaatcctcct attggttcaa caaacttaga tggtacaaca
     1021 cctaacacac tattaataac agtagcaggt tcagatataa caaatcaaaa tatattaaat
     1081 gggcctgtga tttatacacc tatagagaat atattggatt cttgcgtatc tgtatctaat
     1141 ataaacctta ttacagatgc agataacgga acattcggtt tttttccacc aggtacacca
     1201 agtaatacag gacctgaaat agaaccttac ccaaatgtga cgccagattt tacgtatgtt
     1261 gtaccagacc caactaagtt tacaccttta gatggagaat atacagtaca aaatattatg
     1321 acaaatgcaa tgagtaatgt tataggagct tggtggcgta ttgctgacca tactacagga
     1381 aatgaaacag gaagaatgat ggtggtaaat ggttttaatc ctggagctgt attttttaaa
     1441 tcaacagtac aagttacacc taacactaat tatttattta gcacttggat tttaaacctt
     1501 tttaaggtaa caggatatcc accaccacag ctaggtgtaa gaatatttga ccaaaataat
     1561 aatatactat atcaagcaac attaggagct caaattccag ttaatacaaa cgcaccagaa
     1621 tggaaagaag taggtactgt gattaattct caaaataata atcaacttac agtagaattt
     1681 tttagtgaag gagaaagcgc cattggaaat gattatgcta tagatgatgt ttctttaaga
     1741 gaaatagctg ttccaacttt tactccaata aaaacaagta acacagaaac tgctaatgta
     1801 ggtgatataa tcacatatac agttacatta gataatactt gtgatagccc tttaactaat
     1861 gtatttttta gggatttaat tccaaatggt ttagagttta tacctggaac tgtaacggtt
     1921 gatggagtat ctgtaccagg agtagaccct aatacaggtt ttccacttcc agatattgga
     1981 ggaggaacag gggttgaagt aacttttgat gttgtggttg aaagtattcc taacccaaat
     2041 cctactaata atatagctaa tatagattac tcctatacac ctgtagaagg cggtatacca
     2101 aatgattttt cagtagattc taatccagtt cctgttgaag taatatcagc agatattgaa
     2161 gttacaaaat tatctgaacc tactatagtg aatccaggag aggaattaat atacactata
     2221 aaagtagtaa ataatggacc attcccatct gaaaatgtgg ttttaacaga tgatgtacca
     2281 gcttctatta taaatccaga gtattcatta gatggaggag taacttttca accatggact
     2341 ggaagtttaa atatagggac attagaagta ggagagacaa gagttattat aattaggggt
     2401 attgtaaatc catcaacagt aggaattata acaaatacag ctgtggtatc ttcaactaca
     2461 gcagacccaa accttaataa taatgcatct acaatagaga cagaagtgaa tttattagca
     2521 gatattttag taatgaaaac agcagaacct aattcagctg ttccaggtac tttattgaga
     2581 tatactattc aagtagaaaa cttaggacca gcaaatgctg aaaatgtaat attaaatgat
     2641 gatattccag cttctattat aaatccagaa tattcattgg atggaggagc aagttttcaa
     2701 ccatggaatg gaagtcttaa tataggaact ttaaactctg gaatttcatt aacagtttta
     2761 attcaaggaa cagttagttt aaattcttca gaatatatag taaatacagc aacagtttct
     2821 tcaactacac ctgacccaga tttaagcaac aatatatcta ccattattac accagttaac
     2881 ccacaagcag gtatttctat tataaaagta gctgacgagg atgtagctgt tccaggagaa
     2941 gaatttgtat atacaattga aatttttaat gaaggaccat ctaatgctac gaatgtagtt
     3001 ttaacagatg atataccaga tgttatttta aatccagaat attcattgga tggaggagca
     3061 actttccaac catggactgg aagtcttaat ataggtacag ttgcaccagg gcaattaata
     3121 agaattatca taaagggatt agtaagttca actgctacag gagatattac taatacagca
     3181 gaagtaagtg cagatgtacc agaaccagtt acggattcat caacagtgac aactcctata
     3241 gttccatcag cagatataga agtaataaaa actagcaata tggatacagc agttccagga
     3301 gaaactttta gttatactat aacagttaca aatttaggac catctgctgc acaaagtatc
     3361 gttttgacag atgatatacc agatgttatt ttaaatccag agtattcatt ggatggagga
     3421 gtaactttcc aaccatggaa tggaaatctt agtataggca ctttggatgc tggagaaata
     3481 agaagtatta taataagagg aacagtgagc cagacagcag taggtacaat tataaataca
     3541 gcaacagtaa gttcaactac acctgaccca aatccagata ataatacttc aacagatgaa
     3601 acagatataa gtccattagc agatatttct gtgataaaag gcaacgaacc agttgctata
     3661 ccagggagaa gatttattta tggaattgaa attgcaaatg caggaccatc ttttgcagag
     3721 aacgtaactt taacagataa tataccagct tctattttaa atccagagta ctcaatagat
     3781 aatggagtga ctttccaacc atggaatgga agctttaata taggtacttt agatgctgga
     3841 gagataagaa atatcataat aaggggaaca gtaagtcaaa cagcaatagg cacaattgta
     3901 aatacagcaa cagtaagttc aactacacct gacccaaatc taaataacaa tacttcaaca
     3961 tcagaagcag aggtaagttc atcagcagat atttctgtag taaaacgaag caatcagact
     4021 gttgttgtac caggagatgt actagactat acaattgagg tgagaaatgc aggaccttct
     4081 actgctcaga acgtaacttt aacagataat ataccagctt ctattttaag tccagaatat
     4141 tcaatagata atggagtgac ttttcaacca tggaatggaa gtcttagtat aggcacttta
     4201 gatgctggag agataagaaa tatcataata aggggaatag taagtcaaac agcaataggt
     4261 acaattataa atacagcaac agtaagttca actacacctg acccaaatcc agataataat
     4321 acttcaacat cagaaataga tataagttca tcagcagata tttctgtaat aaaattagca
     4381 aataaaacag aagcatgtgt aggagagcaa atagattttg taatagtagt atcaaatgca
     4441 ggaccagaaa atgctcaaaa tgttacttta atagacaatg tttcagataa gcttaagaaa
     4501 gcagtatttt cacttgatag aggtgtaagt ttccaaccat ggactggaag tcttaatata
     4561 ggtacactac cagctggaac tttaagagtg attatattaa gaggaattat aaaatcaaca
     4621 tgtcttgata gattaacaaa tattgcagaa gttacttcaa caacaccaga ttcaaacctt
     4681 aacaataata tatcaagagt gcaagtagaa ataaaacaat gttgttgtaa tgattgctgt
     4741 tgtaacaact gtagtaattg ttgttgcaat gattgtggtt gtaaagattg ttgctgtaat
     4801 tgttgtaaaa atgacttttg gtgttgattt tataaaataa ttttgtatac cttaaattaa
     4861 actgaaataa aaaataaatt cacatatgag taaaatattt tataaatatt aataaaattt
     4921 tctatctttg atat
//
LOCUS       DAEPXW010000175         4792 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.179, whole genome shotgun sequence.
ACCESSION   DAEPXW010000175 DAEPXW010000000
VERSION     DAEPXW010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4792
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.179"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(15..779)
                     /locus_tag="KRM55_003562"
     CDS             complement(15..779)
                     /locus_tag="KRM55_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH1595747.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            1053..1727
                     /gene="fsa"
                     /locus_tag="KRM55_003563"
     CDS             1053..1727
                     /gene="fsa"
                     /locus_tag="KRM55_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH1595748.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTINPSIVSKEKKNFKQLIN
                     EIGEIIGEDIPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(1849..3243)
                     /locus_tag="KRM55_003564"
     CDS             complement(1849..3243)
                     /locus_tag="KRM55_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBH1595749.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(3321..4667)
                     /locus_tag="KRM55_003565"
     CDS             complement(3321..4667)
                     /locus_tag="KRM55_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1595750.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIIAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
BASE COUNT         1862 a          672 c          620 g         1638 t
ORIGIN      
        1 acatataatt aaacttataa aacatttaca ttaaattctg ataaaatatc tactatatca
       61 ggagtaggcg ttttttctgt aattatagaa ctaatatctt ctaaatgagc aaacttgaaa
      121 tttccatcaa atttaaactt tttatcttcc ataactataa atactttttt acttgaattt
      181 attatagcct tcttcgtaag accatcttca atttcaaaag ttgtaagtga agagttgaat
      241 acatctactc cacaacttcc cataaaagtc ttatcaaact tatatttcga tataaactct
      301 atagttggag taccgacaaa accgtctaaa ctgagattta ataaacctcc agtggaaatt
      361 atatttaaat tatttggttt tgaagtaact acatttagta tatccagcat atttgtaaca
      421 agtgttactt ttttattact ttcagctaac aacttcgcaa gcaagatgtt aattgtagag
      481 atatctaaaa atatagtttc tctatcttca attaaattaa atgctttttc tgctattatt
      541 ttctttgttg gaatattaat ttcttttctg tcttttgtat cctgattctc tagtgtttct
      601 ctagctagta cagctcctcc ataaattctt cttattgaag aaatcttttc tatatttttt
      661 aaatcttttc ttatacaatc ttctgtaaca ttaaatttag aactgagctc tttgacagta
      721 actctacctt ctttttttag gatatttaat atagcttgga ttctttcttc tgcaaacatt
      781 ttctacctct tttcgcaata tagtattata gtaaatatta taagataaaa tacaatatat
      841 caactatttt aacatgaaat acaaaattaa tttaatataa aaagtatgtt ttttctaact
      901 atatatttag aatttagtaa ataaaaaaat tataaaacta agaaggaaaa gtaaaacaat
      961 aataaaaaat aaaaaacaat aagcaaaatg ttgaaaataa taccaaatca atatataata
     1021 agaataaaga aagattaaag ggggatattt taatgcaact aatcttagat acaggtaatg
     1081 tggaggagat taaggagtta tgtacttgtt taccaataga tggtgtaact ataaatccaa
     1141 gtattgtttc aaaagaaaaa aagaatttta agcaacttat aaatgaaatt ggtgagatta
     1201 taggtgagga tattcctata catgctcaag tgttaagtac aaagtatgaa gaaatattag
     1261 aagaagcatt atatataagt agtttgagaa aaaatatata tgtaaaaata cctgtaacac
     1321 aagatggttt aagagctata aaagaccttc acagaaaagg tgtaaaaata actgctactg
     1381 caatattcac tgctcatcaa ggttttttag ctgcaaaggc tggagcaaat tatattgcac
     1441 cttatgtaaa taggcttgat aatatatctg gtgatggagt agctatggtt tcagaactta
     1501 taaaaataat agatacttat aaaatggata caaaagtact tgcagccagt tttaaaaatg
     1561 cacaacaagt tatagaatta atgcaacatg gggtgcatag tgttacagta ccatatgata
     1621 tttgtaaatc tatgatgaat catccattaa ctgattggag tgtagataag tttatagagg
     1681 attgggagaa tacttttgga aaaggaagta aaacaaataa tatttagtat tatggtaaaa
     1741 gagtagtttt gtccaatttt acaagaactt atataaaaag atgaaaatat gaattttctt
     1801 tttaataatt tcattattat cttaagttaa ttcatatttt catctttttt agatttctag
     1861 tcctataaat ttccaccaag ggaatgttat acatattatt ataaagtagg ttaaaggaat
     1921 caaagttaaa ccgtatttga aaataacctt gctattatac agattttcac catgaccaac
     1981 cattattgta gcatgatgaa atggtaatat gtactgtatg cttactataa tgtagacaaa
     2041 tagacataaa gtaacactat tttcctttag tatatgtaaa cttccaagta acggtattac
     2101 tacagatgat gtagtgacag cacttccaag acatatattc aagattattg tgagagttat
     2161 caaaaacaat attgaaataa tttctgaaga gtttggtata aactttatca aataatttcc
     2221 cattatatct acaactccag agtactttaa cactcctcca attgaaaatg ctgctataaa
     2281 aaaaataagg accttccaat ttatttcttt taaagtacta aatccaacta tttttcttag
     2341 taataaaaga agtacacaaa ttgacattat aattaatgtg tttatgttat gtatgaactg
     2401 agttaaaaac ataaaaaaca ttattcctag gcataaaaat acgtgttttt gctctttgtt
     2461 tagcaaatta aattcttttt ttaaattaga atatgaaaaa tgaagtttat taccctcaag
     2521 attttcatta gaaataaatt ttattgaatg caattctttt ttaaagacaa agataaataa
     2581 aaaataagtt ataaaacaag taattatagt tggaacagac atataaaaag cccattgacc
     2641 ccaatttata ttacaatttc caagttctag tacaacataa tttagaaggg tgtctccatt
     2701 tacaaaaaac attgatgtaa aggtagatgc tgtaaatata ctaaataaaa gtatagattt
     2761 tgaatcttca gttatctgtt gttcttttaa aaactccttg taaaaagcag atacaagaat
     2821 aacccttgga aatggttgtg ggataaaaaa tattaaaagt atacctaaaa tatacgataa
     2881 aagaatcatt tttttagggg tatttacagt atttaaaatt aacttctcag aaataatttt
     2941 tgcgacacct gtttttgtaa ctgcattagt aattatgtat gcaagaatta ttatgtaaaa
     3001 attttctgta aataaaaact gtaaaataac ctttattggt gcaatgttaa atataaacgc
     3061 tagaattaca aaaaacaatg caacaaaagt tttttcaact gagtctacag cccatatcaa
     3121 gatagttaaa aaagataagc atatagaaaa ttttatgttg aaactgtaat taagagagaa
     3181 gtagagaatt atggtagcta taacagtcat ataaaattgt tttggcttaa gaataatacc
     3241 catttttata ttcacctcca taatttatta tatcataatg gaggtgaata caatgaatgt
     3301 gaatacattt tataaaaaga ttattcattg attctatgat ttacaatagc tttagttttc
     3361 caatgtcctt tcttatagta gataactgta acaataagac ctaaagtcca accaaaagga
     3421 atacccatcc aaattccgtc tgttccaaaa aatttagaaa gcatataaga agctggaagt
     3481 cttccaagcc ataaagatac tattgagctt ataagtgcaa acatggaatc accagcacct
     3541 ttcattgcac ttgaaagtac aaaagaagtt ccaataaata aaaagaatgg tcctattata
     3601 aataagtaag aagagccaat tttaatgaca tctttatcag tattgaatag agcaattaga
     3661 ttttccctaa atagcaaaat taaagcaata actgtaactg ctaaaactaa ggtcattttt
     3721 atagattctc gaatgccttt tttaactctt tcattttctc cagcacctat gttttgagca
     3781 acaaaagtag aaacagcaga accaagattc ataataggta agcttataaa attttctatc
     3841 ctaagaccag caccaaaagc tgccatagca gatgtaccat aactattaac taaaaattga
     3901 agagccatat ttccaattga aaacaacatt tgttgaactc cacttggaag tcctaatcta
     3961 agtccatctt taaatatttt gttatcatat acaattccct tgattttaaa tttaagcact
     4021 tcatgttttt tatttaaata aattatactt attataaatg atactgcctg agctattata
     4081 gtggcaagtg caacgccctc aacacccatt cttaacacta caataaaagt taagtctaaa
     4141 actatattta gaattgtggc tattatcaga aaataaagtg gagttactga atctccaagt
     4201 cctctaagta ttgcacttac tgaattatat ccagcagaaa ataatattcc actaaatatt
     4261 atagtaagat acaattttga ttgagcaaaa acggattctg gtgtattcat aagcttaagc
     4321 atggggccac caaatactat tccaagaata cttattaata tagaaccaat aaataaaagt
     4381 atatatgtag tatcaatagt agcttttacc ttttttaaat ctcctgagcc ataaaattgt
     4441 gacactaaaa tagaaaatcc aaggctaaca cccataagcg ctgccaccaa taaaaacatt
     4501 atagggttag ctccagagac tgccgccatt gcttcttttc caataaatct accaactatt
     4561 atactgtcag ctgtattgta tagttgttga aataaactac caataagcat aggcatggca
     4621 aaaaagaata tggactttcc ctcatgacct gtagttaaat ctttcacctt attcctccaa
     4681 ataaaaaaat tattaattta ttatagtata atcttaacat aaactttata tccaaactat
     4741 aaataaattg tatcaaaata tcatatattt ttttaaaatg taaagaatat aa
//
LOCUS       DAEPXW010000176         4572 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.180, whole genome shotgun sequence.
ACCESSION   DAEPXW010000176 DAEPXW010000000
VERSION     DAEPXW010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4572
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.180"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(184..765)
                     /locus_tag="KRM55_003566"
     CDS             complement(184..765)
                     /locus_tag="KRM55_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595751.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            933..1751
                     /locus_tag="KRM55_003567"
     CDS             933..1751
                     /locus_tag="KRM55_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1595752.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            2493..3314
                     /locus_tag="KRM55_003568"
     CDS             2493..3314
                     /locus_tag="KRM55_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1595753.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEIWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(3624..4403)
                     /locus_tag="KRM55_003569"
     CDS             complement(3624..4403)
                     /locus_tag="KRM55_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH1595754.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         1686 a          656 c          570 g         1660 t
ORIGIN      
        1 ttatatatat aattaaaagg attgtggaaa tcaataaaaa tatccctgta aaaatagcac
       61 tattcatatg gaacttaata gaacttgcat ctgttacctt attattctta atccagaacc
      121 cacaaatcat agttgaaaga aaaagtaaaa cagtgataag acttgaacca atagttataa
      181 ttttcatctt acatcaacat cctctccaat aatattttct attaaaatat caatgaattt
      241 atctcgctca tatttattct ttatatttat accactgtat aactgaaatg attctgtaga
      301 taaagcagaa atctgtattg gtaaaataat ttgcagggca ataattctta gactcatttc
      361 atctttttta tttccaaaaa ttttacgaag catagggaca atatcaagtt ctgcttgcat
      421 atctccattg gttatacatt gattcaatac aaaaggaagc actttttcat aatgtaatcc
      481 agtatcacac aattttttta ataaattttt caaatcttca ataggtctta gagtatatac
      541 actatcgtca tatagctctg ctattatatt tgacatcaca tctcctatgg cagtactcaa
      601 caaattatcc tttgttttaa aatgataatt tattaaacca actccaacat ttgcacgctc
      661 agcaattttt ctaactgtaa tctcctcaat atcatctact tcatttaaaa gattcaatgt
      721 aacttcaatt atacgttctc tagcatcttt atcattactt ttcataatag acctccaaaa
      781 caattaacat tttcagttct gaacatgttc agtataatat ttttttcatc atatgtcaat
      841 ataatttaat tataatttta gttgactcta acattatgat atggtttata ttaatattaa
      901 gctaaaagta cctttataaa ggagacaaaa acatgtttaa gataggcgat ttttcaaagc
      961 taagtaaaat tagtattcgt atgttacgtc attatgatga aataggactt ttaactcctt
     1021 ctcatacgaa taaaactaat ggatatagat actatagtgc agaccaactt tctactacaa
     1081 acagaatcca tgcactaaaa gatatgggct ttggcttgta ttctataaaa gaaattttga
     1141 cagaatataa cgataaagaa agtctcataa aatatctaaa tatccaccat tctcaagtaa
     1201 aagaacaatt agaagataca cagaaaaaac tattaaaaat agaaaccact attaaaagaa
     1261 ttggaggaaa tgatattatg aaaaattatg atgtaactat aaagaatttt gcaccaaaat
     1321 atatgatgac acttagaagg gttataccaa cttatcaaga cgaaggaatg ttatggcatc
     1381 aagcattttt agagacaaaa gaccagaatg ttcaaattga acccccaaag tattctaaag
     1441 cagtctttta tgatactgga tataaagaag attatgtaga tgttgaagta caagttgctg
     1501 tatctggaaa gtataaagat actgaacatg ttaaatttaa gactgttcca agtgtgactg
     1561 ctgcaactgc aattgttaat ggaaatttca atcaagttgc agacgcttgt gaggctattg
     1621 gtaattggat atcagataat aactatgatg tggatggtcc tatgtttaat atttatcatg
     1681 taagtcctgg caacgatagt aatcctgata attgggtaac agaggtatgc ttcccagtta
     1741 aaaagaagta atttttatat taattggata atattttaat ttgttagaca aattactttt
     1801 agtgttgtgt ataaatacct acaatttaat tagtatatta tcttaatttt tcagataaat
     1861 cacttgtgat gttgtgttta aatgactaga atttgattgg gatattatct taatttgtca
     1921 gataaattac ttatgatgtt atatttaaat gactagaatt tgattgggat attatcttaa
     1981 tttgtcagat aaatcaatta taagattata tactatcctt atactctagt taaatatatt
     2041 ttaatcacta atataaatta gtttttttaa caaaacaata aaagagtaaa gtacaaataa
     2101 ttcctttgtg ctctactctt tttaactttc tttagacaat aatacaatga taaatataaa
     2161 aaattatata ttccattcta tagaaatatg ctcaccaata acatgtatgt tgttaatcaa
     2221 tatattatat caaattatat caaaattaca taaaccttat aggacaatca tatcttatta
     2281 caagaaaaat gtcttatcca tattgaataa gtcattcagt tcatatacaa agtcaatttc
     2341 attgagaaac atttaatata tgtttataaa aatttcatac tattctttca tatttacatg
     2401 tgatataatt tattaactca taattttgtt aatcagttgt gcttgtatat tatttatata
     2461 atctaatatt ttaagaaggt ggtgtaataa ctttgaaatt aaaaattgtt ggtagtggcg
     2521 gtatgtcaat tattccaagt tcattttgca aatgcaaaat atgtgaagaa gccagacaaa
     2581 aaggcggaag atatgaacga ttagggccaa gtttatatat tgatgatata aaaatgctga
     2641 tagacacacc tgaagacatt gcagtagctt gtaacagaca aaaaatatcg gaagtaaaac
     2701 atatttcaat ttctcaccat gacccagacc atgttaaggg tattagaatt gtcgaaaaaa
     2761 taggatgtga ctttatcaca ggagaaaata atccaattgg cttttatgcg cttcctgaag
     2821 taattgaaga tataaaccga acgaatctcg attgtcttaa atattatggt gatgttataa
     2881 attgcatttc tattaatgaa acttcgcatg taaagataaa taattttgat attgatttga
     2941 ttaacaataa cccagacagg aatataacct tctatgttat caaagagaat gaaaaaaaag
     3001 tcatatatgc ctgctgtaat cccaagccat ttactcatag tgatatgtac tttgatgctg
     3061 atgttttaat aataagtcta gtttctgatg atggtatatt aaatgatggt acaaaactta
     3121 aagacacacc atttaaagat gaaatattta ctttagatga gattgttgaa attaaaaact
     3181 attatagaat taaaaagatt atcattacac atattgacga aatatgggga aaatcatatg
     3241 gttattacag tgaattagaa aagaaacttg ataacattta ttttgcatat gatggtatgg
     3301 aaattatagt ctaaatcatt aagtaataag cataatgcaa aataagaaaa cttcaattta
     3361 acagtatagt taaactatgt aatatcaaca tatctcagtt tttacaaaat atcatagtat
     3421 ttatctttat aaaatttcaa gtcctacata ttttaatact tcaatatcta aataaagtaa
     3481 aatcaaaaat atattttata tacattatag acggcttatc ggcactagat aagccgtttt
     3541 gtcacaatta ttatttgctc aacaaaactt ctcataatat ataacagatt gaatctccaa
     3601 ctgatactta attaccgaaa ctcttattcc ttaatatgtt gttgcattaa ccaaaccttc
     3661 atcatcattt tttgtggcaa tagttttgct aataaatgac tggattttgt atttatacca
     3721 tacacagaaa tatccttatt tttctttgca tccttcaatg cttttttggc aacaatgtct
     3781 ggagacacta tgcctgggaa attttttgtc cctttttcag ctacaactat acctctctta
     3841 aatagatttg tactcatcca acctggacat acagcaattg catttatccc tttactctta
     3901 agttcaacat ttaatgctct tgtataattt cttataaacg ctttagttga actataaata
     3961 ttttgatatg gcaatggctg gaatgatgct tgtgaagaaa tattcatgat atggcttccc
     4021 ttttgcatat atggaataca tataagtccc aatgctacaa cagcactaat atttaaatca
     4081 atcatattaa tagattcatc tatacttaaa tcattgtatg aacagaattt tgcaaaacca
     4141 gcattgttta taaggtattt tatacataca ttttctttac ttaaaaatgt accaatttct
     4201 tttacttctt ctatttttga taaatctttt gaaaaaattt ttaccttact tccaaattca
     4261 tctactaatt gatttaatct cgccttgttt cttgcaactg cccatatttc tgttatttct
     4321 tcttcattta ttaataactt tagaaactct ttaccaaaac cactattagc acccgttata
     4381 attgcaatct tcttataact cataattatt ctcctttacc ataagtttat acgctcaaac
     4441 tgtaaactta ttttttacaa ataaaacacc ctctattcag atgttatatt catattattt
     4501 gagatattat atttatatca ttttcaataa ttgttatata gcataaaaaa tagtgttaat
     4561 attatagaat cg
//
LOCUS       DAEPXW010000177         4465 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.181, whole genome shotgun sequence.
ACCESSION   DAEPXW010000177 DAEPXW010000000
VERSION     DAEPXW010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4465
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.181"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            36..704
                     /locus_tag="KRM55_003570"
     CDS             36..704
                     /locus_tag="KRM55_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595755.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            863..1369
                     /locus_tag="KRM55_003571"
     CDS             863..1369
                     /locus_tag="KRM55_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBH1595756.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1497..2513
                     /locus_tag="KRM55_003572"
     CDS             1497..2513
                     /locus_tag="KRM55_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH1595757.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2867..3571
                     /locus_tag="KRM55_003573"
     CDS             2867..3571
                     /locus_tag="KRM55_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBH1595758.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     VGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            3866..4345
                     /locus_tag="KRM55_003574"
     CDS             3866..4345
                     /locus_tag="KRM55_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH1595759.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1877 a          376 c          756 g         1456 t
ORIGIN      
        1 gtattttaaa taaatttttt aaagggtgat tttttatgga aaatataact agttatttta
       61 caacaatact atgtgtattt atatgcttat catctgtatt tatatttact caactagcta
      121 gagtatttat taataagaag aagattaatc aaaaaattaa atcaagaaac ggatttaggt
      181 atgatagaga ttttattgaa gccagaagag aagaaataca tataaaggat aacaataata
      241 ataaaaataa gagtaacaat aagaaattaa aggaagaaaa agtatttaaa tacgataatg
      301 gtgatttata taaaggtgag tttgttgatg gaaagaaaaa tggatttgga atatatattt
      361 tttcaagtaa ggaaaagtat gaaggattat ggaaagatga caagatgcat ggaataggaa
      421 aatatactta tagagatggt tcaatatata caggtgaatt taaatacgga ttaaaaaatg
      481 gtttgggaaa attaacatat cccaataatg acatttataa gggatatttt ttagataata
      541 agaaaaatgg taagggtgta ttatataaaa atgatggaaa taaacaagca ggaatatggg
      601 aagatgatga acaatgtaaa agtttagatt ttaaagattt aaataataat aaaataaata
      661 atgtttatca aaatagatta aataacaata aattaaaagt ttaattattc taataaaaaa
      721 atctttattt atgatggaat ataggatata tctatgttgt aatttgtaaa atcttcctat
      781 atcatataaa attaagtatt gattagtcta ttacataaat atagaatata aatatatcca
      841 tttaataata aggagaagag atatgaaaga gtatgtagtt gtggatttag aaactacagg
      901 attagatcca tataaaggtt gtgaaataat agaaatagga ataacagaaa taaaaaatga
      961 acaaattgta aaaaactatt caaggttgat aaaacctaag gggataattt cttcatttat
     1021 aacagaattg acacatataa gtaatgaaat ggtagaaaat gaagaaccac tagaattagt
     1081 tttacctaga tttagaaaat acataggtga tagaactata attgcacaca atgcgaaatt
     1141 tgatttaaaa tttttaaatt actatcttag aatgttagat ttagaaccaa taaacaatta
     1201 tatatgtaca gtagagttat taaaaaaatg taaaagttat aaaggaaaaa acaagaaact
     1261 tgaaacagct tgtgcttatt acaacataga gaatataaat gctcatagag ctgacagtga
     1321 tacattagca actgcaaaac tatttttgaa aataaaagat gaatattaat tataaatata
     1381 gagaaaatta gtgaaaatat cctttataaa attgaccctt aagcttacaa ttttgttctt
     1441 tgatttattt tgtagaacaa tgtataatgt accttatatg aagaagggag actaaaatgg
     1501 gttattacaa tgataatgat aataataaaa taagacgtaa aaaaattagt aacaacaaag
     1561 atagtaataa aaaatctaaa cattcttata cttcggcaaa taaaaaaaat aaaagtccta
     1621 atacaagttc cagtaaaaga atgagtgaaa aagtagattc acagaatctt ataaaaagag
     1681 atagagatag ttttacaaga gataatgtaa gacctttaaa tacagattac aatcaaagag
     1741 aaagaagaag agtcgagtat aaacaaagag agaaaaaatt aaaaagtaaa aaaagaaaaa
     1801 aacaaaaaag gattagaata gttagggcat tattatctat tatgttagtt gcactaatta
     1861 tattttcagt ggcaggtgca atatttacag tttcagctat aaaagggtca ccagaagtta
     1921 ctaaaaagtt aattaggtct aaatatataa gtagtgaggt tgtaagtata aaacaaatgc
     1981 caaatgattt aaaacatgca atagtttcca tagaagatga gagattttat aagcataaag
     2041 gagtagatgt tatttctcta gttaggtcag tattaaacaa tgtgtttaca gatacaacac
     2101 aaggtgcaag tactatagat atgcaagttt caaaaaacct gcttactagt aatgataaaa
     2161 ctatgaagcg gaaaataagg gatatgtata atgctaagca gatgaataag attatgacta
     2221 aggatgaaat tcttgaagca tatttaaata atatgtatct aggtaaaaat gcatatggag
     2281 ctgcaaaggg agctgaagtc tacttcggta aaaaagttag tgaattaaat ttagctgagt
     2341 gtgctatgtt agctggtatg acaaataatc ctgcaaggta tattgaccat ggagaggcta
     2401 agaagagaca agtgattgta ctgtataaga tgcatcagct tggttatata actgataagg
     2461 agtatagaat agcaaaagct gatgacactc catttaaatc tgaaattgat taaaattgta
     2521 agaatatagt attttcaata gtttaaacaa acgaaaatgt aataaaaaag gtgatttgcc
     2581 acccatttgc caccataatt ataatttaat agcaaattgt tttaatgtac aaatcagata
     2641 atataatatt gttttaaata ctacattatg ctaaaattta attgtatttt gtaaattaaa
     2701 aaacttataa tttagttttc tagggttccg cattttataa tggtcaggtc caagagaaaa
     2761 cgcacaattg ttgtgtacac ggaaggataa aagcctggga gatatttaat aatatttcta
     2821 taggcttttt tatttttaca tattttaaat ttgaggaggt tttctaatga aaaaatttgt
     2881 tattgaggat gcattttgga atctatttcc tagtgcaaaa attggagttg ttatttgtaa
     2941 tgatatagat aactctataa aagatgaaga ctataagaaa ataattttga agggagaaga
     3001 agaagcatta aaatacttgg aggactcaga atttagcaac aaccaagtga ttaaagtatg
     3061 gagagaagca tttaaaaaat ttaaaacgaa aaaaggagca aggtcttcta ttgaagcatt
     3121 attaaaaaga gttcataatg gaaataatat aggaactatt aaccctttag tggatatcta
     3181 caattttatc tcattaaaat atgcattacc ttgtggaggg gaggatatag ataaatttat
     3241 aggagatatt aggctaacta gagcaattgg taatgaggag tttatcccac tagggacaga
     3301 tgaaaattca tttccatatg aaggagaaat aatttataaa gatgatgttg gagcgatttg
     3361 tagatgttgg aattggcgtg aagcagtgag aacaatgctt actgaagata ctaacaatgc
     3421 ctttttatgc attgaattag tagatgaaag tagatttaaa gaatttgaaa atgctttaaa
     3481 tgaattagct aaaatagttc aagaaaaatt gggtgggaat tgtaaaattt caattttaga
     3541 tattgataat aaagaggtat cagtggatta atatgtaggt gctgttgtaa tggactattc
     3601 tagttataaa gatacttata tttagggtaa gaaggtctat tttagatata acgattatca
     3661 aaggatataa tatagaaaat aaaaatgtag aatataaaaa gcctttaaaa taagaaaaaa
     3721 atgtatttta aaggctttta ttatactctt ttttatttgc ataattaaca ataaaaatat
     3781 attgttaatt ataatatttt tattgaaaaa cgatataata taatgtatta tactatatat
     3841 aaaatatttt aaaggagttg gcatgatgtc taataaactt ataaaaaatt tactaagtgg
     3901 tatattacaa attttatttt ttcttttagg attagtaatt gttgcaggag gatttaaaag
     3961 ttttatgtac ctctgtttta gtggagaagc aactctacaa ggtactattt atggaatatt
     4021 aatgtttatt ttaggtgtat catattttat cattataaaa tcattgatag aagtattagg
     4081 tagttctgaa tatagcctat ttgtaaaaga gaatgtaaaa agatttagga ttattggata
     4141 tcttttgctt ttaaactctc taattgagtt tatttcaact tttggtacta ctggaaaagg
     4201 aatgagattt ctagatttag gatttggatt ttattttact gttccagtat ttgtatattt
     4261 tataacttct cttatgagtt ttgtaattgc agatggattt gtaaaggcaa taaagataaa
     4321 agaggataat gatttaacta tttagatgtg acactttaat atataggaga taaataaccc
     4381 gaaaagagtg actaactagt aatttaaaat aaaatatatt agggtataat acataaacta
     4441 taatgctaaa attaaaagat tataa
//
LOCUS       DAEPXW010000178         4454 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.182, whole genome shotgun sequence.
ACCESSION   DAEPXW010000178 DAEPXW010000000
VERSION     DAEPXW010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4454
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.182"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     misc_binding    78..312
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            362..1381
                     /gene="pheS"
                     /locus_tag="KRM55_003575"
     CDS             362..1381
                     /gene="pheS"
                     /locus_tag="KRM55_003575"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBH1595760.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     gene            1398..3791
                     /locus_tag="KRM55_003576"
     CDS             1398..3791
                     /locus_tag="KRM55_003576"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBH1595761.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            3816..4406
                     /gene="zapA"
                     /locus_tag="KRM55_003577"
     CDS             3816..4406
                     /gene="zapA"
                     /locus_tag="KRM55_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBH1595762.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
BASE COUNT         1753 a          520 c          918 g         1263 t
ORIGIN      
        1 tgtattggat atatattaaa aatagtcaca taatttgaat ggaaatgata taatactaaa
       61 ataaacaata taatattgta aatgcaatga aagaggaaag tattttgatt aaacttagta
      121 aagagataaa cacctaggct gggagtgttt tctaagaggt catgagaagt tccctctgga
      181 gtaacagagc tgaaatttta cagtaggctt tgacgtcaaa aacgcgttaa gtttgttaga
      241 ggtggtttga tgatttttaa attgttaaac tactagggtg gtaccgcgaa actatagcct
      301 ttcgtcccta gacagggatt gaggggcttt ttttatacaa aaaaacgaaa gggtgatatg
      361 tgtgcaagaa aaattacttg ctttacgtga agcagctttg gctgaaataa aagaagcaca
      421 aagcatagaa agtgtagaaa gtttaagagt taagtactta ggaaaaaaag gtgagataac
      481 tgccatactt aaagaaatgg gtaaattatc tgctgaagaa agaccagtag ttggtaaggt
      541 tgccaatgag gtaagagaaa acattgaact tagcataaat tctaaaaaag aagaaataaa
      601 tgctattgaa aaagaaagaa aattaaaaga ggaagtgata gatgttactc aaccaggaaa
      661 agttttaaag gttgggaaga agcatccaat aactcaaatt atagatgaag taacagatat
      721 atttatcgga atgggattct ctatagcaga agggccagaa gttgagactg ttgaaaacaa
      781 ctttgacgca ttaaacgctc ctaaagacca tccatcaaga gatatgagcg atacattcta
      841 tatcaatgat ggggtattac ttagaactca aacatctcca gttcaagtaa gaactatgag
      901 aagtcaagag ttaccaataa aagtaattgc accaggtaga tgttttaggt cagactcgcc
      961 agatgctaca cactcaccaa tgttccatca gatagaaggg cttgttgttg gaaaagatgt
     1021 tactatggca gaatttaaag gaactatgga tatcttcgtt gaaaaattgt ttggttctga
     1081 tatcaaaact aagtttagac ctcacaactt cccatttaca gaaccaagtg cagaggttga
     1141 tgttacttgt ttcaaatgtg gtggtaaagg ttgcccaatg tgtaaatatg aaggttggat
     1201 agaaatatta ggttcaggta tggttcatcc aaatgtgctt agaaattgtg gaatagaccc
     1261 agaagtttac agtggatttg catttggagt tggggttgaa agacttgcaa tgcttaaata
     1321 cgaaatagat gatattagat tattattcga aaatgatatg agattcttaa atcaatttta
     1381 attaggaggg tatgtagatg ttagtatctt taaaatggct tagagactat gttgatatag
     1441 acatggatgt aaaagagttc gctgataaaa tgacaatgac aggaactaaa gttgaaacaa
     1501 tagattatta tggtgaagaa atagaaaata tattggttgg aaagatttta gaaataaaac
     1561 aacatccaaa tgctgataag ttggttgtaa ctaaagtaga tattggagat aaagttgttc
     1621 aaatagttac aggagctaca aatatatcag aaggagatta tattccagta gctgtaaatg
     1681 gttctaagtt acctggagga gttgaaatca aacagactga tttcagaggt gaattatcag
     1741 atggtatgat gtgttcagca gctgaactag gtatagatga acattacatt gaggagtata
     1801 aaagaggtgg tatatatatt ttagaccacg aagattctta tgaattagga aaagatataa
     1861 aagatgtttt aggattaaaa gatgctttaa tagattttga attaacttca aacagacctg
     1921 attgtaaatg catgatgggt atagctagag aagcagctgc aactatagga acaaaagtaa
     1981 aatatcctga aatcgaagta aaagaaagtg acgaagagat agatttcaaa gttgagatag
     2041 ataatccaga tttatgtaga agatatgttg ctagaatggt tacagatgta aaaatagaac
     2101 cttctccata ttggatgcaa agaagactta cagaagcagg agtaagacct ataagtaaca
     2161 tagtcgatat aacaaacttc gtaatgttag agcttggtca accacttcat gcttttgata
     2221 taaatcaagt agagactgga agaatagtag taagaaatgc taaagatgga gagaaacttg
     2281 taacattaga tgatgttgag agaacattag acaaagatat gctagttata acaaatggag
     2341 aaaaatcact tggtttagct ggtgtaatgg gtggtgctaa ctcagaaata acttctaata
     2401 cgaagactgt actttttgaa agtgccaatt tcaaaccaga aaacataaga atgacagcta
     2461 aaaaagttgg tattaggtca gaagcatctt caagaaatga aaaagactta gaccctaatc
     2521 ttgcagagat agcagcaaat agagctgcac aacttgttga aatgttagga gcaggaaaag
     2581 ttttaaaagg tgttgtagat gtatatccaa ataaaccaga acctaaaaaa ttggtagtaa
     2641 atcctcaaag aattaaccac ctattaggtg tagatgtacc aatggagcag tttgtaggaa
     2701 ttttagaatc attagagttt aaatgtaatt tggtagctaa tgataaatta gaaatagatg
     2761 taccaagctt tagaacagat atggaacaag aagctgatgt atgggaagaa atagctagaa
     2821 tttatggatt tgagaatata ccttctgtac aattagaagg aaatacgaca gcaggaatta
     2881 aaacttcaaa acaaaaattc atggatgctt taaaagataa ttcaactgct gtaggattaa
     2941 atgaaatatt aacatattca tttgtaagcc ctaagggagt agataagata agagtaccag
     3001 aaggtaatgc aaagagaaat tttgttaaat tacttaaccc attaggagaa gaaacttctg
     3061 taatgagaac tactttaata ccaaatatgt tagatgtttt atcaactaat gtatctcata
     3121 aaatagaaga agtatctgca tttgagtgtg gacatatatt catcccacaa gattcagaat
     3181 tacctaagga agaaaataga atgtgtgtag gtatgtatgg taaagatgtt gacttctttg
     3241 cactaaaagg aactatagaa actatacttg taaatgtcgg atttaaaggt tatgaaattg
     3301 aacctcaaga taataatact accttccacc ctggtagatg tgctaaaata gtgtataata
     3361 ataaatatgt aggtacatta ggtgaattgc atccagatgt tatagaaaac tacaatctag
     3421 gtcaaagagt ttatgtcgct gaaatagata ttgactttgt atttgataat tctgatagaa
     3481 caaagaatta tgtgccatta ccaaaatatc catctacatc aagagatata gctcttattg
     3541 ttaaagatga tgtatttgta aaacaaatag aagatataat aaaggaaaat ggtcaaggat
     3601 tagtagaaag ctacaagtta tttgatgttt acaaaggttc tcaaatagaa gctggataca
     3661 agtcaattgc atattcaata acttatagaa gtaaagataa aactctaaca gatgaagatg
     3721 tagctaaggt gcatgataag atattaagtg aattaagcga aaaattaaat gctaacttaa
     3781 gatcaaatta acaactaatg tcgggggagg ttaggatgaa caaagtaatg gttaaaatcc
     3841 atggcgctga atatccaatg gttggagaca aatcagagaa gtttatgatt agtattgctg
     3901 attttgtaga caaagaaatg gataaaataa cacgtcaaaa cccgaaattg agcttatcag
     3961 ttgctgcgat attaactgca ttaaatatat cagacctttt atttgaatgt tcagatgaga
     4021 atgagaagtt gattaaagcg aatgaagaat tgagtaagaa ggttggagca tctaatgaag
     4081 agcttcaatt agaaatcaaa tctttaaagc ttacgatagc agaaaaagaa gcagaaaatc
     4141 gtgaagctga aactaagatg aaagagttaa ttgagattat agaaaataaa aagcaagaaa
     4201 tattcgaact tagtaatacg acagaaggtt ctagagcaga gttagatgct tataaaaaca
     4261 agattgagga gttaagtact caacttgaag aagcaaatga aagagctact atagctgaaa
     4321 acttagcttc tgagtttcaa aacaaagctt atgatttaca gttaaaatgt acagggttaa
     4381 ataatgatgc aaaaaatgtg gaataaacta aaagatttgc tgtctcttgt tttttgagac
     4441 agcttctttt aatg
//
LOCUS       DAEPXW010000179         4372 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.183, whole genome shotgun sequence.
ACCESSION   DAEPXW010000179 DAEPXW010000000
VERSION     DAEPXW010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4372
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.183"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            231..1310
                     /locus_tag="KRM55_003578"
     CDS             231..1310
                     /locus_tag="KRM55_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH1595763.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINIQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSITIIINGVEKGKLDFELGV"
     gene            1634..2002
                     /locus_tag="KRM55_003579"
     CDS             1634..2002
                     /locus_tag="KRM55_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH1595764.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2119..2916
                     /locus_tag="KRM55_003580"
     CDS             2119..2916
                     /locus_tag="KRM55_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1595765.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQL"
     gene            3315..4205
                     /locus_tag="KRM55_003581"
     CDS             3315..4205
                     /locus_tag="KRM55_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1595766.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFDAVKELNDSGIFCGILLTPMLPFLTDTKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKEIIKAYKRSESYTQIKFF"
BASE COUNT         1662 a          484 c          828 g         1398 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaatttat atggtttata gtttaacagt aggaaatatc
      121 gtatgagtga gaatatcgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagtatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg gtcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagcattta
      601 tcatcaagga tgaagaacgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggtt gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacctg tactgcctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgcaaagg attggtatgg taaaaataaa tctactaact
      901 ggattgtaaa gcatggttgt agaactctgc taaaaaaagg aaatcgtgat gtattagctc
      961 tttttggata tgatgatact acttcaataa atattcagga ttttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatccactcg attactatta
     1261 ttattaatgg ggtagaaaaa ggcaaacttg attttgaatt aggtgtataa ttttactaac
     1321 agcataacct atatcagata ctttgctaaa cctatatcat atattctaat aaatctatat
     1381 taggtagttt actacttgtt tactaaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tgcaataccc atataaatta gaatttgtag
     1621 aggagaaatg taaatggatg tatatagttt ttggaatgac actttggcac aagatgctgt
     1681 taagataaga aaatattttc atgaagatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaagg gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaacca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggatga tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtgtttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccaa atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gataaacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaatttttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgctgaaa
     2641 atgttagaag gctacgaaaa aaaagaactg tgtcatctca tgtatctggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaataa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttataatata taaaaattac atacccatta
     2941 ggtaaattat gtagtatatg tgtttacaga tggttataga aataaatatg taataaacta
     3001 cttaacactt aaaaagtgga tttgtccaga gtataataca aagcatgata tatataaatt
     3061 tttaagcgaa atacatcaaa agaaggatta gaattagtgg agacagaaca gctattatag
     3121 attataaata aatagtttta aaggagaggt actacgaata tagaggaagg taaatcatac
     3181 gttattcaag tattataaat gattagttta aaagtactat cgaataggag tctccatatt
     3241 taaaccttag taaaggtagt taaagtagta gtttaaaaac taaaaaatta tataaaggaa
     3301 ttaggtataa gaaaatgatt gagagtatac cagcaaaaca aattttacaa aaagtgaaat
     3361 ttgacaatac aagatggttt ggaattgact ataatatgaa tctctatcgt ggttgttctc
     3421 atggatgtat atattgtgat agccgtagca caatatacaa catagagaat tttgacaaag
     3481 ttagatataa agaaaatgtg atagaaattt taagtaaaga attgcgttca aaaagaaaaa
     3541 aaggggtagt aggcattgga gctatgtctg acacatataa tccttttgaa aagcaacttt
     3601 gtattacaaa gcaggcacta gatttgattt cggaaaatca ttttggagtg tctattgata
     3661 ctaaaagtag tttggtggtt agagatatac cgattttgca gaaaattaaa aaaaataatt
     3721 ctgctattgt aaagttgact ataaccactg caaatgatga attatcaaag aaaatagaac
     3781 cttatgtaaa tccaagttct gtacgatttg acgcagtgaa agaacttaat gattctggaa
     3841 ttttttgtgg catattatta actcctatgc ttccattttt gactgatact aaagatgaaa
     3901 tacgagcaat tgtagaaaaa gcacacaagg ctaatgcaaa atttatttat tgtatgtatg
     3961 gtgtaacaat gcgtagtggt cagcgagagt ttttttatga gcatttaaga gatatatcac
     4021 caaaattggt acttaaatat cagaaaacat atggtttaaa ctatgtatgt actgtacaaa
     4081 ataaagattg ttgtgagaag ttgttaagag aagaatgtgc acgttatggt attttgacgg
     4141 atatgaaaga gattataaaa gcgtacaaga ggtcggagtc atatactcaa ataaaatttt
     4201 tttaagatag gctttggatg agatataata gtggtgattg atgtgttgat attatagttg
     4261 attgttagag aggatattat agatgaatat tagtattgat attttaggta attgctagag
     4321 ctgatattat agatgaatat tagtattgat attctaggta attgctagag ct
//
LOCUS       DAEPXW010000180         4287 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.184, whole genome shotgun sequence.
ACCESSION   DAEPXW010000180 DAEPXW010000000
VERSION     DAEPXW010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4287
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.184"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(237..1280)
                     /locus_tag="KRM55_003582"
     CDS             complement(237..1280)
                     /locus_tag="KRM55_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBH1595767.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(1301..1747)
                     /locus_tag="KRM55_003583"
     CDS             complement(1301..1747)
                     /locus_tag="KRM55_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBH1595768.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(1921..3501)
                     /locus_tag="KRM55_003584"
     CDS             complement(1921..3501)
                     /locus_tag="KRM55_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBH1595769.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIGMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
BASE COUNT         1391 a          758 c          400 g         1738 t
ORIGIN      
        1 accatgctta tttgctatat gttttatata atattatata acacttttta cattagtaaa
       61 ggataaattg tataaagatt ctgttaattt atttttataa tttcatcttt ctaataaaaa
      121 caaagaagaa gacttaaaaa tttataagtc ctcttctttt caacgtgcat ttttgtgcta
      181 tatttaatta attcgacctt taatttccat atccttccta tgataacaaa actcttttat
      241 ttttttaatg attcattatc atttaaaact tcttttatat caagtacttc tttgttatca
      301 tcactcataa cttcctttat tcctttgaat gttcctagga aattaactgc ttctgaaggt
      361 aaaaccagtt ttgttgactt accttcagcc attttttcaa gagcttccat agattttaat
      421 gctagaatat tattgtctat atcagcctct ttcattgctg aaaaaactaa ttttaaacct
      481 tctgctgttg ccatttgagt tctttttatc atttcagctt caccttgtgc cttagcaata
      541 gctgtctgtc ttatagcttc agcttcacct tctgccacta atatagcaga ttctttttca
      601 ccttctgcta cacgtaccat agcttctttt ttggcttctg ctgttaatat agcagattgt
      661 ttttcacctt cagcttgaag tattgcagct gacttattac cttctgcttg aagtattgcc
      721 tctcttcttt ctctttctgc tctcatttgt ttttccattg caacttgaat atcctgagga
      781 ggcattatat tttttaactc tactctattt acttttatac cccatttatc tgttgcttca
      841 tcaagaatag ttctcatttt tacatttatt atatctcttg atgttaatgt ttcatctaaa
      901 tcaagttcac caattatatt tcttagtgtt gtagctgtta aattttcaat agcagctatt
      961 ggattagcta tctcaaacac atatctaact gggtctgtaa ctttataata tacaactgta
     1021 tcaatctgca tagttacatt atctttagtt ataactggtt gaggtggaaa atctattaca
     1081 atttctctaa ggtcaattac atatgccatt ttatctaaaa atggtattaa gaaatgtaca
     1141 cctgtttcag ccactttttg aaacttacca agtctcatta ttatacctac tttagattgt
     1201 tttataactc ttatacaagt taaacttatt gctacgacta ctactattaa tacaatactt
     1261 aaaacaattt tagtacccat actataaatc ctcctttatt ctattggttt gtcacattaa
     1321 ctgtggcgtc tactttttta acaactaatt ttaccccttc aatttttaat acttctactg
     1381 tagaaccttt ttctatcttt tcaccatcta tagaaatagc cgtccatgtt tcatgttcaa
     1441 ctacaactag acctgtgtta tttggagaaa tctcttctgt aacaatacct tttttagaca
     1501 tcattgcttg taaattagtg ttagatttat agcctttatc tttttttact atttttttag
     1561 tagctacgac taacattgct atagaaatta ctgcaaatat taaaatttgt aagaaaatac
     1621 tctctataaa gctacttaaa aatataagta ttacagctcc tacactaaac catatcaatg
     1681 ttaagcttgg tgttaacatt tctgctattc caaataagac tgctactatc aaccatatta
     1741 gcttcatact atctaccctc ttttcatatg aattataaaa ccctatataa attatatgtt
     1801 tatacaatgt ttttgaatat aaatttaaat tacaaaacaa taaaataaat taattaatta
     1861 atagtattat atcaacatac tttgttaaaa ttgttacaaa gtagtatcaa atatcaccaa
     1921 ttatatatcc aacaactctt tcattgttaa tgaaatgtta cttattaaat ccgtagcatt
     1981 taccgtatac attgctttgc tcaatttatc tcctatatag ccatgtatat atgctccact
     2041 aactgtagct tccaatatat ccataccttg acctataaat gaagtaatca ttccaagcaa
     2101 acaatcaccc attccaccag ttgccataca gctatttcct gtaggattta tatatgtttt
     2161 tttaccatct gttatgacag tttgataacc ttttaaaagc accaccagat tatatttttg
     2221 agcaaattct tttgcaacat ctactctatg ttctcttata tacccaattg aatctcctgt
     2281 caacctggcc atttctccca aatgaggtgt aattacaaat ctatttttcc attctaaaaa
     2341 cttataacat ctgtccttca taacgttcaa tccatctgca tctaatacta ttgggcaatt
     2401 agaattttct actatcttaa gtaatttatc aaatgtttga ctattatctc ccatacctgg
     2461 accaaaacca attgcatcac tagaattaag taatttattt aatctttctt cttcaaaatt
     2521 taaagtcatt gcttctgtaa gtctaataga taccttttct tgcacatctt cactactaat
     2581 taatgttaca agtccactcc cactcttaac agcagattca gttgctatga aacttgcacc
     2641 ataaaatcct tttgaacctg caactataga tacttttcca aaatcacttt taaaaccatg
     2701 cttatctctt cttctaatat tattttttac aaaagtctta tcagttatga actcttcatc
     2761 atggtatttt cttgtaataa aatctggaac acctatcttt tctacaacta catcacctat
     2821 aagtgtgcta gtgtcatagt ttagaaaacc tcttttataa aactcaaagc taatcgtttt
     2881 gtttgctcta atacaagttc ctaatacatt tccattatcg ctatctatac ctgaaggaat
     2941 atctatagaa tatgtatttt tactattatc gtttactatg tcaataactt ctttaaaaat
     3001 accagttata tcacgtttta atccagtccc aaatatagca tctactacaa catcactttt
     3061 agatactcta tctttaaaaa ttgttaaatt tttatttttt ataatatttt gtttctcaac
     3121 tttaataatt ttatctactt cattttcatc tccataattt ttttcactta aatcattttt
     3181 attaatattt ataatattaa ttcccatatt taaaagtaca ttgtaattta ttttagagca
     3241 ttcacttagt ttttcaagat tacctactaa aaatacgttt acttcttttc catatgtatt
     3301 tagatgtctt gctattccaa gaccatctcc tccattattt ccaacaccac atacaactgt
     3361 ataactatta tacatgccta tatccatatt tttcattgca gatataaccg cattttccat
     3421 caatacaatc attggaatcc ctacttcttc tacacatgca gtatcaacat ttctgcttaa
     3481 tttagatgta cctattagca taaattatca ctcctataaa gttaaagact tcttaaatac
     3541 ttaccaaaaa tatctattga aatcttttta atcccataaa tatcataaat aaaatcacta
     3601 aaactaagag ttttgaaata atttaaaata acaaaaaatt ttgaattaaa acaattattt
     3661 aatttattat accatataat ttaagttatt atgttgattt aaaacctatt tacactaatt
     3721 atctaaatat ctctttattt ttataatctt ttatgactta tttatatttt tcatttttat
     3781 aaaaaaacaa taattaagaa tataactata ttctacatgt aaaaattttt ttatttaaac
     3841 tcaattttct gataatttga taatttttca aaatttatag ttgactttta ttttttactg
     3901 tattaaacta attactatac aaaacagaaa acaaaatttt caaaattatt aaattaaaag
     3961 gagaggtaaa tatgaagact ttattaaaca aacaagtacg attttttagt agccaattta
     4021 gttagggttt gtacctaagt taagacaaat tgtcataaca tagatacaaa ccccttagga
     4081 ttatgatttt taaggattgt atctatgttg gctatagtaa ttgttgttaa agtttttatt
     4141 ttatcatcat aatatagagc cacatggatt atactgtgtg gcttattcga atttttgcca
     4201 tacagttata tatactgtgt ggttttttta tatcaaaatc attttttaaa accaaattta
     4261 aaaaaccatt taaaatattt tcaaagg
//
LOCUS       DAEPXW010000181         4277 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.185, whole genome shotgun sequence.
ACCESSION   DAEPXW010000181 DAEPXW010000000
VERSION     DAEPXW010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4277
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.185"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            462..941
                     /locus_tag="KRM55_003585"
     CDS             462..941
                     /locus_tag="KRM55_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1595770.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            938..1717
                     /locus_tag="KRM55_003586"
     CDS             938..1717
                     /locus_tag="KRM55_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595771.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFIPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(1967..2467)
                     /locus_tag="KRM55_003587"
     CDS             complement(1967..2467)
                     /locus_tag="KRM55_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595772.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(3067..3774)
                     /locus_tag="KRM55_003588"
     CDS             complement(3067..3774)
                     /locus_tag="KRM55_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1595773.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
BASE COUNT         1560 a          641 c          460 g         1616 t
ORIGIN      
        1 tctctatcta aaataatgac atttctaact cttaattctc atttaagttt cattgttttt
       61 tcttaaaagc ctacttttag tcaagatact gttatcttta ctcattattt aaagaactta
      121 ttttaaatct gtacatgaag taaataatcc aaaagcattg ttattctaac tactcaacat
      181 taaatactta ctattttcta attactcaat ataaagactt actataaaac taaatacata
      241 aatggcttct aaagtttaat atatctacat ggctttatat atgacaggaa aaatactaga
      301 aaaaatatat tatagaatac ttgtatataa taggcaaaac tttcaaactt aaatttatca
      361 aataatcata aaaaaagtga accatctata gtaaaatttt atctaataag tgaaaggcaa
      421 aaaagtagcg ctacgatttg catagaaggg aaggaactta gttggataaa actacattta
      481 caaacaatat acttgaatca gaacagactt tgtatcgagt atctaagtct attctaggaa
      541 atgaccaaga ctgtgaagat gccgtcaaca atgctatttt aaaagcatat gaaaagttgg
      601 attctcttaa ggaagaacaa tactttaaaa catggctgat tagaatagtc ataaatgaat
      661 gtaattcatt aagacgcaaa cgattaaaat ctctatcatt tgaagatgtc ttcaaaaaca
      721 aaaaaattga tgaaaaagat gactatagcg atttgtatac tgctattcaa agtctaccta
      781 aaaaaattaa aattccaata gtcctttact atattgaagg ttattcagta gatgaagtta
      841 aggaaatatt agatatacct caaggaactg taaaaagtag attatcaaga ggaagaagat
      901 tattaaaaac taaattagaa aacacggagg taatcatatg aataaaaata tattaaataa
      961 ttcgtttcca gaagttccag aaagttttca taatagttta agcaaaacac taaatagttt
     1021 accagaaaga gaggaaaatt ataaaatgat taataataaa acacacaaat taccatttag
     1081 aaaaggctta gttgcaactt tagccattac tttgatattg agcacaacag cccttgcagt
     1141 aggacatata tatagtttag ttggaaaatc aagtactaag gctacctata catctatccc
     1201 aactacagaa caagtaaaaa aagactttaa ctttacccct aatatagttt ctgaatttag
     1261 taatggatat aaatttaaag gagcatatac tgtaaataaa aaagcatttg acaaagaaaa
     1321 taatgtttta ggaaaatcaa aagcacttag ttttgaatat aaaaatggca atgatgaaat
     1381 atctcttgac acagcaaata atgtacttgg gaagagttct gacaatctaa aagttgtaga
     1441 tacttacaaa gatattaata tttcttatga agcattcgca caaaagttta taccagaagg
     1501 ttataaaatg acagaacagg ataaaattga tgaaaaatca ggcaaataca catttagtgt
     1561 ggggccaaat aatgaatcag acaaagttga agttaatgaa tttaagtttt tgacatggaa
     1621 acaagatgga gtttactatt cttttacagt tcaagactca aatttatcta tgaatgactt
     1681 agttaaaatg gctcatgaag taatagatgc aaaataaaca taagtaataa taagttgttt
     1741 atgagtttat tatttatgac tttaattttt ttattagtaa acatggttgt atcttccatc
     1801 tttatatttt ctttaaattt aatatataaa attttagata tttagctacc ttcaaaagaa
     1861 gcattattaa aaagccctta aaaatatttc ttttatatgg aattttaagg gctttaactt
     1921 tattttatac aagtgtatat ggaattttaa agactttaac tttattttat ataagtgtaa
     1981 gctccatttg aattacttct tcttttacag gtctatcatt ccatgtaaaa ccactagata
     2041 ttgtatttac ctctacaaac cctaaagatt tataaacatg aatagctcta ctattacttt
     2101 taaatacatc aagctcaatt ttttcatacc catattcttt tgataaatca ataatttgtt
     2161 ttaaaagact acttccgata cctttttccc tatactcttt aagaataccc atgcctaaat
     2221 aaccaacttt ttcagtttta ggtaaaacgt cacaccaacc aatacagtta tctgattcta
     2281 aatcaattat aaacagttgt ggtaagtttt tatttataat attttttata aattcaactg
     2341 tttcttcaaa aggaaaggct tcatccatag ctagatattt cctctctttt gctattttat
     2401 caaaagtttg ccaatacgaa taaatatact tttcttctgc ctttataaat tttatgcctt
     2461 ctatcaactt aacatttccc ctttttaatt tttgattgta gttaacttat tttatatgat
     2521 tctagtttat aatgctatat aaattactat atattagctt aaaatatctt tgtatatttc
     2581 tataaaatta aaaccaatat atctatctct tgcatctcta ttaaaataat ttttaatagt
     2641 ataataaata tagttcttta atcttttggg tatatatact taatcatttt gaaatttgat
     2701 ttaaagtata ataaaatata taaaatggta ctataaaatt tttaatcttc atcaatacct
     2761 tttttgcttt cattgttaaa actatttttt ctattagttt atttcttata aaacaaacat
     2821 ttagtattaa aatatatatc acacaatagt atttgcaatt taactttaaa aaaataaaaa
     2881 tacccaactg acctaagcaa ctcgattggg tataaataat ctaaaaaatc atttttgtat
     2941 aaactcttta tttaacttac atttttattt accttctact ttaattcaac ttatatttct
     3001 atgcttctta tactctcatt caacttatat ttctacttat cttatacttt tataaattca
     3061 tcacaattat ttagttctcg ctatcaaaga aattgtatta aaatactttc cattctctac
     3121 ttccatcatt tttttgtcat ttatagcata tgaattatca caatttatcc aatccttcca
     3181 agcttcatca tgacaattta aagcttcaca tttctctaca atcacagact ccgattcaga
     3241 ccaaagttta ttccaccatg taattgaatg gaagttcata ttatcttgcc aaaatggaat
     3301 gagttcatct ggtatacaat ccacgaaatc ttcttttaat ccaggcattg ccatagcaag
     3361 tattcccccc tcttttacaa gaggtgatat atgattgtct aaaaatcctt ctttgtttcc
     3421 aaaatagtga taagaatcga tacttatcac cgcatcaaag aaaccttctg cataaggtag
     3481 ttcatgtgcc tctgcctgta ttggaaatat tttatcatcc aatttaaact ctttaaatct
     3541 tttatagttt tcagttggtt ctatccataa atctgttgca aatacagtag catcaaattc
     3601 ctttgctaaa aatatcgaag atataccctt accacaacct aagtctaaaa tacgcattcc
     3661 cttttctagt tttatcttac ttgttaattc ttccaatatt tttatacaat taggtcccat
     3721 catatttttc atgagaaagt ccttatcgta tttattactt tttgtaaata tcattctatc
     3781 tttcctttcc ctatcagtta ttatttatta aattttatac gtttgatttt ttatttttta
     3841 tctgcttctt atattgagca atctcttttt tattcattct ttaacagaca attttaatgt
     3901 gtaattttat ccactctgtg atagtaactt taatgaataa tcttatctac tgtgatagtt
     3961 attttagtga gtaattttat ctactccaca gcaatcgctt taatgagtaa tcttatccac
     4021 tctatgatag ttattttagt gagtaatttt atctactcca cagtaatcgc tttaacgagt
     4081 aatcttatct actctataat agtcacttta atgagtaatc ataattttta tatcatttta
     4141 gatacttact ctaataagaa ttcattttct aatacttaat aagttttaat tacttccact
     4201 ttaacctata tactaattaa cttatttaat ttagtgcata tttgacactt taccttttat
     4261 tataccattt attatca
//
LOCUS       DAEPXW010000182         4173 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.186, whole genome shotgun sequence.
ACCESSION   DAEPXW010000182 DAEPXW010000000
VERSION     DAEPXW010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4173
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.186"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(192..410)
                     /locus_tag="KRM55_003589"
     CDS             complement(192..410)
                     /locus_tag="KRM55_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595774.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            complement(411..818)
                     /locus_tag="KRM55_003590"
     CDS             complement(411..818)
                     /locus_tag="KRM55_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595775.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            complement(904..1392)
                     /locus_tag="KRM55_003591"
     CDS             complement(904..1392)
                     /locus_tag="KRM55_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBH1595776.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     IAVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            complement(1597..2718)
                     /locus_tag="KRM55_003592"
     CDS             complement(1597..2718)
                     /locus_tag="KRM55_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH1595777.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIEKGIAKGKR
                     EEKFNIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            complement(3092..3262)
                     /locus_tag="KRM55_003593"
     CDS             complement(3092..3262)
                     /locus_tag="KRM55_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595778.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            complement(3434..3877)
                     /locus_tag="KRM55_003594"
     CDS             complement(3434..3877)
                     /locus_tag="KRM55_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595779.1"
                     /translation="MIEIKTIEINKKSQIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
BASE COUNT         1430 a          692 c          366 g         1685 t
ORIGIN      
        1 tctataagct ttctttttca tctataaatc attcattctt taatccatta gcttggtttt
       61 tcatctataa gtcatttatt ctctaatcta taagcttggt tttttaccta taattaattc
      121 attctctaat acataaactt gaatttttta tctattaatt cattctctaa tgcataagta
      181 atacatgaaa tttaaatatt attttcttca ataaattcaa acaactcttc tacagttgta
      241 tcaaatacct tagcaatatc cattgccagt tttaaagaag gattgtagcg accattttct
      301 aaatgtacaa tagtttcacg tcttactcct actgactttg caagttcacc ttgtgtcata
      361 aggttctttt ctctatagga tttaattttt gtctttagta atactgacac ctaattgtat
      421 atcccctttc tgtcaaaata tataaataga attaacttca acaaggattg aataaacaaa
      481 atgactaata aagacattcc tatatttaaa tttgacacat ttatgtccaa agttacaaga
      541 aatatagata ctatagctac agaaaaaaac aatactttta ttgcaatatc attaactctt
      601 gatagtatac attttgatgc ctcatcaatt aaatcatcat actttttatt atagacccac
      661 tgagctccca tagctaatac ccaaataatt ataggaagat attcaatact acttccttta
      721 aaaaaatact tatttactaa tgtagctcca atacaataag aaattcccaa tatttctgaa
      781 ataagtgttg atttaatacc agtttgttgt ttagacatat aaaatccccc ttaaaaagtt
      841 atgtatttat aacacctctt gttataaata tataactttt ttgaataaat ttcaataaaa
      901 atattatttt gcaacaaatt cttttattaa ttttacatta gatagaggca ctttagatgt
      961 cactccttgc aatgtcaaat cttctatatt aacttcattt aattttgaac acagttctaa
     1021 gtcaaatatt ctttcccaac ttaccttctt ttcaatttgt tcatcttcat aaagctctac
     1081 agcaatatcc attaaaggta aatgccataa atcaaattct gataataaca cattatcttc
     1141 acttatttct atttcaagta aaacaccttt ttttcctttt tctaaataac cactacatct
     1201 taaatcaggt ctcttcgtcc aaacccatat catactatca tcaaattcat atattctatt
     1261 tgtcatttga ctatacatcc atttgtatgg aatatcaaag tcttctaata taaaagaata
     1321 atcatttgat agatatttat tgtttttatt gttattccaa aattctaaag tctgtatagt
     1381 ataaaatttc atatataaat caaccccttt gtttttctat aagaaggaga tggttcaaac
     1441 ttttattttg aattatctcc tttatttata cacctctttg tacctattat ttatatatct
     1501 ctttatatct accatattta aatagcaaag ttttatatta atttaaattt aaaagaggaa
     1561 gctttgtatt tatctagtgc catctcaatc atagtattag ttttgattat agactttttc
     1621 aacctctgat ttattcaaat catctataat atcgcatatt tcactcaaat tgtatccttt
     1681 attttttaat tttatgatga tattaaattt ctcttctctt ttcccttttg caataccttt
     1741 ttcgatacct ttttcgatac ctttttcaat accttcttga aaaatttctt ctttaaaatt
     1801 tctactttta ttcataatat acgcacctct ctttaaattt aataaatagt cctcattact
     1861 acctaattct tttaatctat caagtgctct tttaataaca taatccgttt tagatagtat
     1921 tctaatatct atatgagaag gattatcaat aagtttaccc catattagaa ctctgtttgc
     1981 tatacaactg gatttacgaa tttttggaag ttctataaaa tataatgcag ttttactaga
     2041 aaaaatatct ggatgcccgt ccattgttaa tctcaggcaa tttacataat cttctatgtg
     2101 attatatttt acatgattta gtatatgtat tccaacagtt tttccaattt ctttatattc
     2161 tttaccttct tctaactttc taccatgtac acgactaaga taatattcag ctctttccaa
     2221 ataatcctct tcaagagctc tttgcatctc aatatttata tggttacgtt cttcatcttc
     2281 agccaaaata tcaagtctag gtcttttctc accaatgtaa ttaattgttg ggtcggtttc
     2341 aaccttaatt attcttttta tttgagtgaa ctgtttgata ttcctattag catatggagc
     2401 atctttgagg atatcattta taaaatttgc aagtaaatcg taatcattat ttaaagtaaa
     2461 caatgattta aatacctcat catactcagg cttagcatac ccatcttcag ttacaacttc
     2521 tccaacattt tcactagtca atatttcttt tggaattaaa tccttgattt tatctaattt
     2581 ttcattagaa aaatcacctc tactaagtat gtcatttaat tttttggtcc attctctgtc
     2641 cttttcttca attatagttc gtttatactc ttttgatgtt ttaataatct tagatttttc
     2701 ttctaatttt tctttcatat caacacctct tttttattat tacccatttc ttcatcccaa
     2761 agtctgaact tctaagtaaa atttgcatta ttgaaataag aaccttataa acttatatat
     2821 cattactaaa gttaagactt taaagagaag cacttagatt acaatagatt ttagatagct
     2881 ttctttttaa aactcttgtt gataaatgaa tgaatataag agtatgtatt aaaatagaga
     2941 tactcatctt tttcattgtt taagtaatga aaatatattt tatttaatac aaaaaagagt
     3001 gccttataaa ctaaaaagtt cacttcgaga cactcactta cgttttgttt cttaaacttc
     3061 acaatattac atacttattt attaatttaa tctatgcata cttaacccaa taataaagta
     3121 catatatcca actcattaag ccatgaaaaa tagcccatgg aatagatttc catgcagtat
     3181 aagaaataat cattgctaaa caagaaccaa aagaaatacc ctttttaaca gttgatttta
     3241 tagtattatt atttgaatcc ataattaatc ctccaaaatt caaaataaac aagttattat
     3301 atatcttatt tgaatctaat acaatataac agcttctaaa taaattatac tcttattata
     3361 cataatttat aaattataat tccgataatt atatgaatta attaattata ttaacctaaa
     3421 aatattatcc tatctaaaag ttatatgata gatacaacat gtcaacacat tgtaattctc
     3481 cttcaaagat tggttctgga taattatcta caaaaaagtt tttaatttta tgtgaataaa
     3541 caaatccaaa cttctcataa aaaggaactc cgctttcaga tgtaccaaca accattgatg
     3601 aatatttttt actataaaca tctaaaagat gataaatcat ctttgaggca taacccatat
     3661 tttgaaaatg ctcatatgta gcaatgtttt ttaattcaca tatttctttg gaaatttcat
     3721 ttacaactgc tatacaagta agttctttat tatcatacaa tgcgtacata gttcctttat
     3781 tgagatattt atcaatcatt tcttcacatg ggtcggctaa cattaaaagg tcaatttgac
     3841 tttttttatt tatttctata gtttttattt ctatcataag ttctccaccc tcactttatt
     3901 caaaccttaa tttaacaaac ttcttacagt acttatttag ttcattttga tatatatttt
     3961 tactttttaa aatatagtga taattcccta gaatattaat actaataata aattataata
     4021 tcatctctag caattaccta gaatatcaat actaatattc atctataata ttagctctag
     4081 cagttaccta gaatatcaat actaatattc atctataata ttagctctag cagttaccta
     4141 gaatatcaat actaatattc atctataata cta
//
LOCUS       DAEPXW010000183         4131 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.187, whole genome shotgun sequence.
ACCESSION   DAEPXW010000183 DAEPXW010000000
VERSION     DAEPXW010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4131
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.187"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            178..1581
                     /locus_tag="KRM55_003595"
     CDS             178..1581
                     /locus_tag="KRM55_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1595780.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1672..1912
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1955..2653
                     /locus_tag="KRM55_003596"
     CDS             1955..2653
                     /locus_tag="KRM55_003596"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBH1595781.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2676..3677
                     /gene="trpS"
                     /locus_tag="KRM55_003597"
     CDS             2676..3677
                     /gene="trpS"
                     /locus_tag="KRM55_003597"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBH1595782.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
BASE COUNT         1551 a          460 c          734 g         1386 t
ORIGIN      
        1 cttttaaatt tatcattttt aataagattt gatttcaaag tatttaaggt ttattattaa
       61 aactgttttt gaatatgcaa atattctgaa aaatatcagt ttaataataa tgaatctatt
      121 ttattaattt tgaaattaaa tttaaaataa ttaatagaga ggggaaatta aattaggatg
      181 gaaaagaaaa aaataggcct atggagtttg gtatttatga atgtatcagc tttatatggt
      241 ataagatgga tagctaaatc tacagcatca agctttggtt taggattagg tgcaatacct
      301 atgtggttat tattctcatt tatatacttt gtaccaggag ctttaatttg tgctgaatta
      361 gcttctacat atcaaaaagg tgatggaggt ctttacgatt gggttaagga agcctttgga
      421 gaaaagtatg gatttttagt ttcttggtta aactggacag ctaaaatatt ttggtattct
      481 tcatttttaa ctttcttagc agtaaatgtt tcttatacaa taggaaatcc agcccttgct
      541 gataataaga tgtttgtact tatattatct ttaataatat tctgggcatt atctcttata
      601 gcaactaaag gaataagttt tacaaaaata tttactaata caggtgcatt aggttcaaca
      661 ataccaagtg ctatacttat aatattttca tttgtagcag tatttgtgtt gaaaaaacat
      721 gatatagctt ctacatacac aatagcttca atgactccaa aacttaatat ggatgcattt
      781 gttgctatat cagctataat gtttggttta gcaggagcag agactgctgc taacttcata
      841 acagaaatag ataagcctga aaagaacttc cctaaggcaa tattaatatc agctggaata
      901 gtagcttcat tatatgtatt aggttcaatt gcaataacaa tgataatacc accagaccaa
      961 attactgctt ctaaaggtgt attagatgca ctttctgctg tttgtgcgtc tttaggaatt
     1021 ggttcttggt tggttcaatt aatagctttt ggtatagctt tttcagtatt aggagcaata
     1081 gttctttaca tagcatcacc aataaaaatg ttatttggta gtgttaaaaa aggaatattt
     1141 ccagatagtt tagtagaggt aaatgaacac aagatacctt ctaaagcagt tatacttcaa
     1201 gcaataatag ttactataat actattggtg actacattaa tgccttctgt tgatgctata
     1261 tacaatgttc ttgtaactat gacagcatta actgcattat tcccatatgt attgttatat
     1321 gcttcttata ttaaactaag aaaagagaga ccagatgaaa ttagacctta tactatggca
     1381 aaatcaacaa gtacttgcct aggtttagca aaaatggttt tagttgtaac tgtagtgggt
     1441 atattattat ctgcagcacc agttatgcct acatttgctg aaaatgttat atatgagata
     1501 gagatgattg gtggaggtct tctagttata ttatctggtc tatggttatg gaatagatat
     1561 gaaaagaaaa cagctaaata aaatgtattt taaaaatttc ttttggatat tataatatat
     1621 agttgacaat ttatagtgta aggaatatta taaaataaag aaattaataa attaaatcct
     1681 gagataagaa atagtaaata aatatatttt tgcacagaga attaaggatg ctgagaactt
     1741 aataaaaagt atttattgaa tgggtctttg aggagtaaaa tgaaatgtaa tttaatatta
     1801 cagagtattt gatatcgtgt atgcacgtta tagcatatat taagatatat atattcaatt
     1861 ttgagtgtat ataaatttag gtggtaccac ggaaaatata tccgtcctat tgatttagga
     1921 cggatttttt aatatagaaa atttaggagg aaaaatgaac gtaataggaa ttataggtgc
     1981 aatggatgaa gaagttagta ttttagttga tttaatggat attagagaga ctataaaaaa
     2041 agctagctta gaattttata agggaatttt ggaaggtaag aatgtagtgt tagtaaagtg
     2101 tggcataggt aaggttaact ctgctctttg tgcccagata ctaataagcg aatttaaggt
     2161 tgatgctatt gttaatacag gtgttgcagg agctttaaac gaaaaacttg atgttaatga
     2221 tatagtaata tcaactgatg ctatacagta tgatgtagac actacagcat ttggagaccc
     2281 taagggagtt ataccaagaa tgaagacttc tgtatttaaa gcagatgaaa gacttataga
     2341 tgctgcttac aaatcttctg tggaagaagt aaagactcat aaagtattaa aaggaagagt
     2401 agttacagga gataaattta taaattctaa agaattaaaa gaagaattag taaatgattt
     2461 tggtggatat tgtggagaaa tggaaggtgg agctatagct catgtatgct atttaaataa
     2521 tactccattt gtaataataa gagcaatgtc tgataaggca gatggaagtg ctgatgttac
     2581 ttatgatgta tttgtacatg atgctgccaa taactctaaa gacatagttt taaatatgtt
     2641 aaaatcaata taaatatata aggaggtaca aaaaaatgag tgaaaaaaaa gttatattta
     2701 gtggtgcaca gccatcaggc aaaatgactt taggaaatta tttaggagct ataaaaaact
     2761 ggactgaact tcaagacaat tatgattgtt attatagtat agttgatttg catgcaataa
     2821 cagtacctca agaccctaaa gttttaagag ccaatactat agaattactt gctcaatata
     2881 tagcttgtgg attagaccca gaaaaaaata ctatatttat acaatcacat gtcaaagagc
     2941 atgttgaact tatgtgggta ttgaatacta tgacttatat gggtgaatta agtagaatga
     3001 ctcaattcaa agataaatca caaaagagtg aagcaaatct aaatgcaggt ttattcacat
     3061 atccagttct tatggctgct gacatattgt tgtatcaaac tgacctagtt ccagttggag
     3121 atgaccaaaa acaacattta gaattagctc gtgatttagc aaatagattt aataatagat
     3181 tttcacctac ttttgtagtt ccagaaggat actacccaaa aggtggagca agagtgatga
     3241 gtttgcaaga gccaactaaa aaaatgagta aatccgattc aaatgaaaat gcatttatac
     3301 tattagcaga tgattcagat tctataaaga gaaagataaa aagaagtgtt actgattctt
     3361 taggtgttgt aaaatacaat gatgaacaac caggtattaa aaatctaatt gatatatatt
     3421 ctaatttaag taaaaagagt gtagaagaga ttgtaaacat gtatgaagga aagggttatg
     3481 gcatatttaa agaagatgtg gctgaagtag tatcagaagc tttaagacct ataagagaaa
     3541 aatatgttga ccttcttaat aataaagatt atttagaaaa aatatatagt atgggagcag
     3601 aaaaagccga aaaacaagct agaaaaactc ttagaaaagt ttataaaaaa gttggattta
     3661 tagagagaag atactaatta ttagctatct ttacttgata aataaatttt aaagttatta
     3721 aaaaggtata tgatatgaaa gagagagtct caaagtgaac ttttgttcat gaggcactct
     3781 tttttgtatg aaataaaata tattttaatc atttcaacaa tgaaaaagag gattatctct
     3841 attttgagac agcatctttt gataataaaa aaagatgagc ttttgctcat ctcaaagggg
     3901 ttagattatt cttactttgg ggaaagtaga ataaaggtaa aagttaactg atgtcaactt
     3961 tgtctttttt gcatatcact actgagcata aaaaaatcag aaaaccatag ccttctgaaa
     4021 caacttctaa catacattgt attttatacc caatatgtaa tttatgagtt aattttaact
     4081 cttataatga aaattgtcaa taatatatca aaaaaatatt ttttaaattt a
//
LOCUS       DAEPXW010000184         4016 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.188, whole genome shotgun sequence.
ACCESSION   DAEPXW010000184 DAEPXW010000000
VERSION     DAEPXW010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4016
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.188"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            140..1276
                     /locus_tag="KRM55_003598"
     CDS             140..1276
                     /locus_tag="KRM55_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595783.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            1269..2816
                     /locus_tag="KRM55_003599"
     CDS             1269..2816
                     /locus_tag="KRM55_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1595784.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            3150..4016
                     /locus_tag="KRM55_003600"
     CDS             3150..4016
                     /locus_tag="KRM55_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1595785.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
BASE COUNT         1467 a          451 c          720 g         1378 t
ORIGIN      
        1 tatatttgta gcaatattca gacaaatagt gacctaaaaa tcgtactttg tttacataaa
       61 taaaatagta tgatataatt ataaaaacaa cttataatat tgaagaaggt tgcttgttcg
      121 aaaaagggga tgataaatta tgatagagat aagaaatgta acaaaaaaaa taggaaataa
      181 tgttatatta gatgatattt ctctagttgt agaaacaggt acattggtag ttttgattgg
      241 ttcaagtggt tgtggaaaga ctactacttt gaagcttata aacaaattaa taaaacctac
      301 atctggtgag atatatatta atggcaaacc aatttctcag gaaaatgaaa tagagcttag
      361 aagaaaaata ggatatgtta tacagaacac aggcctattc cctcatctta caataaaaga
      421 aaatatagag ctaattccac gcctaaaaaa ggaaaaatcc gttgaagaaa ttgaaaaaag
      481 aacgttgcaa ctacttgaga tggtaggact tgatagtgat gaatttttga ataagtatcc
      541 ttcagaactt agtggtggac agcaacaaag aatcggtgtt gcaagagcca ttgctactga
      601 tgctgaaata atattgatgg atgagccttt tagtgcttta gacccaataa cgagaacatc
      661 tttacaagaa caattatttt ctcttcaaga tgaattgaaa aaaactataa tatttgtaac
      721 tcatgatatg gatgaggctt taaagatagc tgataaaatt tgtattatga aggatggaag
      781 aatagcacaa tatgatactc ccgaaaatat acttagaaag cctgcaaatg actttgtaaa
      841 agattttatc ggagaagata gagtttggga taatccagaa tatataaaag caagagatat
      901 tatgataaaa aatcctattg ctgttaattc tactagaact gtaactcaag gaatagaaat
      961 tatgagaacg agtaaggttg atagcttact aattatagat agagcaaaaa cattaaaagg
     1021 tattgttact gtaaaagata tgaaagatat tgatgataag tcaatattac ttgctgatat
     1081 tatgtcaagt gagcctttgc atgtaaatga aggtgataat ttagtagaaa tactaaatgt
     1141 aatgaatcgt aattcggttg gatatattcc ggttatttct gatgaaaata aactggtagg
     1201 gcttattact agaagtagtt tactttctgt tttaagtgaa caattcttag aaatggaggt
     1261 gagtgttctt ggctaatttt tttaacttta tactattaca aaaagataag attatagagc
     1321 ttttaataca acatatgagt ctaactgtta catctatttt aatagctata atagttggtg
     1381 ttcctcttgg aataattatt tcaagaatct catctcttag aaagtttgta cttggatttg
     1441 taaacttagt ccaagcagtt ccgtctatgg cacttttggg tcttcttgta cctatacttg
     1501 gtataggaag taaaccagcc atatttatgg tagtggttta ttcattacta ccaattgtaa
     1561 aaaatacgta tataggtata acaagtattg acccagtagt attagaatca gctaaaggta
     1621 ttggtcttac aagaaatcag acattattta aaatacaatt tcctttagcg cttcctataa
     1681 taatgggtgg agttagaata tctgcagtta cagctgttgg tttgatgact cttgcagcat
     1741 ttataggtgc tggtggtttg ggatatttag tattttcagg ggttcaaact gtaaataata
     1801 atatgatttt agcaggggca atcccatcat gtataattgc actgttagtt gattatttat
     1861 ttagtaaaat tgaagttgca gttactccaa aaggattaaa tccaaaagca cctaagaaga
     1921 attatatagc acttaaagta atatctgtag tggttgttgt ttcaatgttg ttcgttgttt
     1981 ttagttctag tttttcaagt aaaaaagata caataactat tggttctaaa gattatacag
     2041 aacaacttat acttggtaat gtttatgctg aattagtaga aaaaaatacg aatcttaaag
     2101 ttaagaagaa tttaaatcta ggtggttcat ctgttgcgtt taatgcaatt aaatctggtg
     2161 agttagacat gtatgttgac tatacaggta cacttttggt aaatgtaatg aaacatgctc
     2221 cgattaaaga tgctgatgaa gcatataatg ttgtaaaaga tactatggaa aaagaaaatc
     2281 agttaacttt acttgaccct cttggattta ataatactta cacattagct atgatgcctg
     2341 aaactgctga aaagtatgga ataaatacta tttctgattt gactaaatat ggtaaagaat
     2401 ttacattctc accaactttg gagtttgaaa atagagaaga tggtcttgta gggctttcta
     2461 gagattatgg tttaaaattc aaagatgtaa aagcaatgaa tggaagttta agatatacag
     2521 ctttagataa taatgaatct caggttatag atgcattttt aactgatggt cttattaaaa
     2581 agtttaatct taagatatta gaggacgata aaaatttctt tgtaccatat tatgcagcac
     2641 cattagtaag agaagatact ttgaagaaat atcctgagtt agaaaaagtt atgaatatgc
     2701 tttcaggaaa aataaatgaa gaaactatga gagaacttaa ctatcaagtg gatgaacttg
     2761 gtaaatcacc agaagaagtt gctcattcat tcttagttaa agaaggctta gtataaaaaa
     2821 ttaatagttt atatcaaaaa tttaagggag tgtctcaaaa tgaacttttt agttcatgag
     2881 gcactctttt ttatatgaaa tcaaatatat tttatcattt caacaataaa aaagaagatt
     2941 atctttattt tgagacagtc tcttattttt atgtatacca aaaccatacc tacgattttt
     3001 atttataatt aagtttcaaa tagaatgaac aagtacaacc aattttgaat ataaatatag
     3061 taaatgtgct tatatacgat tttattgtct ggttgattga tattgataga tagctttctt
     3121 tattgaatcg aagggagggg gaatttgtta tggataacta taagaaagtg aagcaagtat
     3181 tgtggataat tttatttgct aattttgcag tagcattatt aaaaatcatt attggtaatc
     3241 aaataaaaag ctatagtatg acagcagacg gatttcattc tttgtcagat ggagcatcta
     3301 atatagtggg gcttataggt attttctttg catctaaacc aaaagataaa aatcatcctt
     3361 atggacataa aaagtttgaa attataacca gtttatttat aagtggtatg ttgtttgtta
     3421 tagcaattaa gataattctt agtgcagtgt taagaatagc taatccagtt gtacctgcta
     3481 taactataga aagtttaatt gctttaatta ttacactttt tataaatatt tttgtatgca
     3541 tgtatgaata tagaattggg actaaactaa atagttatgt tttgatttcg gattcattgc
     3601 atacaagaag tgatatattt gtgtctctag gtgtattggt tactttagtt ggtgttaagt
     3661 taggatttcc agtaataata gaatctatag ttcctattat tatttctgca ttcataattt
     3721 attcggctta tggaatattt aggccatcta ttggaatttt ggtcgataga gtggctgtag
     3781 atgaggatta tataaaagaa attgtgtttg aatttaatga ggtaagggat gttcacaata
     3841 tcagaagtag aggtagcaaa agttctattt atattgacat gcatgtaatg gtagatccat
     3901 ttataagcgt agagcaatct catgatttaa cacataaaat tgagaaacaa atacaagaag
     3961 aaattaatga aaatgctcaa gtaatagtcc atattgaacc tttttatagt ttttaa
//
LOCUS       DAEPXW010000185         4006 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.189, whole genome shotgun sequence.
ACCESSION   DAEPXW010000185 DAEPXW010000000
VERSION     DAEPXW010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4006
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.189"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            22..420
                     /locus_tag="KRM55_003601"
     CDS             22..420
                     /locus_tag="KRM55_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1595786.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKKYKLNARNVK
                     INLNIKGYKFLPYVKNLQASRDNLCFKINTNIDEPKKYLEQNEIQIERGIVECTGVFG
                     NIKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            408..1346
                     /locus_tag="KRM55_003602"
     CDS             408..1346
                     /locus_tag="KRM55_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH1595787.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFRLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1730..1954)
                     /gene="secG"
                     /locus_tag="KRM55_003603"
     CDS             complement(1730..1954)
                     /gene="secG"
                     /locus_tag="KRM55_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBH1595788.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2559..3851)
                     /gene="eno"
                     /locus_tag="KRM55_003604"
     CDS             complement(2559..3851)
                     /gene="eno"
                     /locus_tag="KRM55_003604"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBH1595789.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1371 a          648 c          461 g         1526 t
ORIGIN      
        1 ataaaatctt aaggagttgc catgataaaa aaaatagaac atgtggtcat tactaataat
       61 aatatagaaa attatatcaa tttttataaa aaatttggtt tttcatctaa agaaatgagc
      121 aaaaagtata aacttaatgc tagaaatgtt aagataaatc ttaacataaa aggttataaa
      181 tttttacctt atgttaaaaa tttacaagca agtagagata acttatgttt taaaataaac
      241 acaaatattg atgagccaaa aaaatactta gaacaaaatg agattcaaat tgagcgagga
      301 attgtagaat gtacaggtgt ctttggtaat ataaaatcta tttatttgaa aaaaactaat
      361 ggaaatttaa ttgaattatc aaatcataga atcacggaga gtaaaccttg gaaaatttaa
      421 tcctatcaat aaatgttgtt cttcctttgt ttctcacaat gtcacttgga tatgttctaa
      481 aaaaattagg tctatttgat actcatactt taaataaaat gaataatgtc tgcttcaagt
      541 ctttcttgcc attattatta ttttttaata tatacaatac agatttagat ggttctctta
      601 attttaggct tatggctgta gctgttataa ttattttttc aatcttctta atcttagtct
      661 ttattattcc taaaattgaa aaagataata agacaagggg tgcattaata caaggtgtat
      721 ttcgtagcaa tttcgttata tttggtattc ctgtgacaat ttcactattt ggcgataaga
      781 gtattggagt cacatcttta ttaattgcag ttattgtacc tatgtttaat gtattatctg
      841 ttgtaattct tgaaattttt agaggtggca aagtaaatat aaaacatatg attaaaagcg
      901 tcttaacaaa tccactcata atcgcctctt ttataggatt gacaatgcta attttaaata
      961 ttaatatacc tacattttta cacaaaacta ttggtgatat ttctaaaata gctactcctt
     1021 tatcacttat aattctaggt ggctctttta gtttttctgc tataaagggg catataaaac
     1081 ccattatatt gggcgtatgt ggaaaactta tacttgtacc tgctatattt ttaccaatta
     1141 gcatttttct tggatttaga aatgtagaat tagcttcact tatgataatg ttatctgctc
     1201 caactgcagt ttcttcattt acaatggcac aacagatgga ttctgacagt gaattagctg
     1261 gacaaattgt agtatttact tctggatttt ctataattac agtattttta ataatattta
     1321 ttttaaagca gaataatctt atttaatgat atttgataac acaaattggt attatgagaa
     1381 acatatataa aattgattta actgcgtaaa aacatattat tatactattt ttactatata
     1441 atataacttt gtgtatatta tctcattaaa catggtgaaa atagtgttgc tatatatttt
     1501 ttagtttgaa gaaaatatat aaatacaaac aatatataaa tacaaataat aagtgccaac
     1561 aaatagtcaa tctataaaat aaaaactgga ctaatcatat aaaatcatta gtccagcttt
     1621 tattttacgt actttttatg ttgatgtact tttattaaaa actaaattta atttttaaat
     1681 gtctagcaaa tgcactaatt aaataatggc cagttattca acaatatcac tacttcttaa
     1741 ctataagtaa tgccaatgca tttataaaaa ataatactgc tgttatcttt gtaactctag
     1801 caagaaatgc ttgttttcct tttggtttaa agtaagcttg acttccttct ccaccaaatt
     1861 ctgaaggtaa agcattctta gaatcttgag gcattatgct aattactagt aaaatcccta
     1921 gtactacttg cacacccatt aaaatgttgc tcattcttgc ccctcctatc tgtttattac
     1981 ttaaatttca ttactcttta gtgtatcaca ataatatagc catttcaaga ctattatgct
     2041 ataaataaca tacaaaaaaa tatattgtta ctataatata ttactatatt ctcaatataa
     2101 aaatgaataa aacttagaag agaaaactat ttaaattaat acataaatta atgcataaat
     2161 taacacttaa aataatctac tctcattgca tatattataa atagccacca aaataaaaca
     2221 atcattttaa aatattgata taacttttaa tttcaacata atttaaaata aataatccac
     2281 atttagcaat aatactttaa tgacaattat gattaaatca aaatatgtct tcacttttat
     2341 tttttaataa aaacctccta tgcaattaga taaaaatgag atagaaacat ttattcatat
     2401 tttttctgaa tctatgaata aaattaagta ataaaatata aaaaaggata agtgccttga
     2461 aaaatcaatt aacacttatc tcttttatat cttataagat gagcttaaat atcttatatt
     2521 ctctcttcat taatcttttt tagtaaccat tttaataact atttttttaa gttatagaaa
     2581 gattttaatc cacaatatct agcttgctct ccaaccattt cttctattct taataattgg
     2641 ttgtacttag caactctatc agttcttgat ggagcaccag tttttatttg accagcattt
     2701 actgcaacag ctaaatctgc tatagtagaa tcttcagttt ctcctgatct gtgagatata
     2761 acagcagtat atcctgctct cttagccatt tctatagcat ctaaagtttc agttattgta
     2821 cctatttgat taactttaac taatatagag ttagctactc cattttcaat tcctttttct
     2881 aatctctctg tgttagtaac aaataagtcg tcaccaacta attgtaattt attacctaat
     2941 ttttcagtta ataatttcca tccatcccaa tcttcttcgt ctaaaccatc ttctatagtt
     3001 attattggga agttgtttga ccaatcttca tataaagcaa ccatttcagc agcagttaac
     3061 tcttttcctt ctcctgctaa aacgtatttt ttagtttctt tgttgtacat ttctgtagca
     3121 gcaacgtcaa gacctaacat aacgtcttca cctggcttat atccagcttt tgttatagct
     3181 tcaactatta attctaaagc ttctctgttt gaacctaagt ttggagcaaa tccaccttcg
     3241 tcacctacac cacaagctaa tcctttttct cctaaaactt tctttaacga atggaatact
     3301 tctgctccca ttcttaaacc ttctttgaaa caacaagctc ctactggtaa tatcataaat
     3361 tcttgaacat caacgttgtt atcagcatgc tctccaccgt ttaatatgtt catcattgga
     3421 acaggtaatt gtttagcatt tactccacct aggtattgga ataatggtaa acctatttca
     3481 tcagcagctg ctctagctac tgccattgaa acacctaata tagcattagc tcctaattta
     3541 cctttgtttg gagttccatc taattctatc atgattgcat ctatagctgg ttggtcaaat
     3601 gcatccattc cttctatttc aggtgctatt atttcattta cgttagcaac agctgtttct
     3661 acaccttttc ctaagtatct tcccttatct ccatctctta attcaacagc ttcaaaagct
     3721 cctgtagatg ctcctgatgg aactattgct cttcccattg ctccatcttc taatactact
     3781 tcaacttcta cagttggatt tcctcttgag tctaatactt ctctagcata tactaattca
     3841 ataactgaca tttgtatatc tcccttcgat tttctattag ttaaattttc atttactgta
     3901 aacatccgtc tactatttta atctactttc tatattatag tacataaagt tgcttttgaa
     3961 aattaggtac aaatttattt gatgggtaaa tttgtaaaag ttccta
//
LOCUS       DAEPXW010000186         3937 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.190, whole genome shotgun sequence.
ACCESSION   DAEPXW010000186 DAEPXW010000000
VERSION     DAEPXW010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3937
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.190"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            71..943
                     /locus_tag="KRM55_003605"
     CDS             71..943
                     /locus_tag="KRM55_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595790.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            940..2211
                     /locus_tag="KRM55_003606"
     CDS             940..2211
                     /locus_tag="KRM55_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595791.1"
                     /translation="MNLFIKECKNILKSMIYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGNIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKL"
     gene            2159..2803
                     /locus_tag="KRM55_003607"
     CDS             2159..2803
                     /locus_tag="KRM55_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595792.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3070..3534)
                     /locus_tag="KRM55_003608"
     CDS             complement(3070..3534)
                     /locus_tag="KRM55_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595793.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKNNFSLA
                     KEDKRKNFISFINDNKELIGFISLLDEGSSVFFGIGMKPNYCGMGIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
BASE COUNT         1482 a          464 c          598 g         1393 t
ORIGIN      
        1 attatgaaaa tacagtaaaa atttataaaa ataaaattct ataaaattgt ttctgggggt
       61 gtatttatat atggaaatga aaatagcagt atccaatctt agtaaaagat ttgggaaaaa
      121 acaagctctt gataatataa atcttgaaat cgacagtggt atgtttggtc ttttaggaag
      181 aaatggagca ggaaaaacca catttatgag aattttagcc actttattat caaaaacaga
      241 aggttcaata catatgtgtg gagttcctat tgagaatact aaggaaatta gaaatatggt
      301 tggttatttg ccacaagact tttcaatgta tcctaacatg acagtatata aagcaatgga
      361 ttatttagca gttttatcgg atataccact aagaaaaaga agaaaaatta tagcaaagtt
      421 attaagcaaa gtaaacctta ctaattatca aaatgtgaaa gtaaaatctt tatctggagg
      481 tatgaataga aggcttggga tagcacaagc attaattcat aatcccagag ttttaatagt
      541 agatgagccg acagcaggtc ttgacccaga agaacgtata agatttagaa atttactatg
      601 cgaaattgca aatgatagaa tcgttatttt atctacacat attgttggag atatagaagc
      661 tacatgtgaa aacgtagcta tattgaatag tggaaaagtc atatacaatg gctcaacaga
      721 agcattagca aaactagctg aagggaaagt atatagtatt gaagtagata aaaaagatat
      781 tgaaaatata aaaagtagat ttatagttat aggaatgttg actcatggtg gaaaggctat
      841 acttaggatt atatcagatg ataaaccttt tgagacagca gtaaattgta atccaactat
      901 tgaagatggc tatatgctta taatgggagg agataatata tgaatctatt tataaaagaa
      961 tgtaaaaata tattaaagag tatgatatat tatattttta ttgtagtttt agtttttttc
     1021 tatatttctc aacttggaag ttcagtttca aatgatgtaa gtaaaaatat tcctaatgat
     1081 ggaaatccat tagttgctcc acaaaaagta gagaatattg aggaatatta ctctgtacac
     1141 aatcaatatc catatggtca aaaagaatct atgaaaacag aaaaagtcat tccaaatgca
     1201 actataaacc taattagaga atatcaaaaa aacacatata caacgtatcc aacaggggta
     1261 gttaagtata taaaattaga ccaaaataaa acgaagacca tagaaaaata tatagaagaa
     1321 ataactggta aaagtattag cgaaataaat tcactttgga aaactgatga aagtataaaa
     1381 atagattatt ctaaagtatc tcttgaaaga tttgaagaaa taatgcaaag agtagacgac
     1441 attttaggag gagggtctgc atatgctttt gacaagttac aaagatttgg agtagttcca
     1501 gttacctatg atgaagctat gaagaattac aactatacaa tacaaaaaga taaagttagt
     1561 aatgggtatg caagaatttt ttgcgattat ataggtatag ttttaagtat atttccagta
     1621 tttgtggcag tttttatgtc acttaaagat aagcgttcaa gaatgagaga gattatttat
     1681 tcaaaacaag tatcttcatg caaaatagtt ttatcaagat attttgcact tgtctttatg
     1741 atgatattgc ctgtattaat tttaggtatg aaagatttac ttcctttgat tttctttgct
     1801 aaagataaag gtatatctat tgataactta gcatttataa aatatacatt atggtggata
     1861 ctaccaactc ttatgatagt tacagctgta ggaatgagta ttactatatt aacagataca
     1921 ccagtagcaa ttattgtgca attaatttgg tggctttaca gtataaattc tacaggactc
     1981 aaaggtgatt attcaacaat ggggctaatg ataagacata atagtgtatt aaatgggaat
     2041 attattatac aaaacttcaa tcaaattatg attaatagaa ttgtgataag cttgggagca
     2101 ttggtgcttg ttttgttagc tatattctta tatgagcaaa aaagaagggg gaatcttgat
     2161 gtttgggcaa agttttcaaa actgtttagt tctaataaaa gaaaacttta aattaagcac
     2221 tttaactaat ttaatatgtt caattatatt gctatgtatg attcctctaa tacaaggagt
     2281 agctaattta gacagaattt caacagctat atgtttagaa aattatgttg caataatagg
     2341 gatagtaatg ttggtacctg tattttcgct agagcaatca aaagaaattg atgagatagt
     2401 atcttcaaaa gcattatctc aagttattgt acaattaatt aggatactga tgtcaattat
     2461 aggtatagtg gtattaatca taggttttgt aaatgtttta atatatcttg gatgtaattt
     2521 tccagtagtt gagtatatta ttggaagttt cgcatcagct atgtttatag gaagtttagg
     2581 aatgtttttc tcaaatttat ttaataatac aatcataggt tatatgatat ctataggata
     2641 tttaatttta aatatgatga ctaaaggcaa gtatgttgga aaatttttta taatgtctat
     2701 gagtcaaggt agttttgatg agaaatattg gctgatactt ggaagtgttg tgttgataat
     2761 tgcatctctc ttaataaaac cagtaaaaag gaagattaga taataaaatg agagcttaga
     2821 taaaataaag gtaatacaaa taaaaggtac atttatgaaa tataaatcta tttttatata
     2881 cacaaaccta cttacaatct ctttatgtat gtagatagat ttatatatcc gtagtataaa
     2941 atatatatgt ataccaaatt ttatcaaaag ctctcaaatt tatatttcaa agacacttat
     3001 tgctatgacc tacacatatg tattttttta ttttaattgt tgtattaaca ataagactat
     3061 tgttataaac tattgatacc tcataacaaa aaattctcca tctcctaaat gcgttttctg
     3121 taccttagtc tcaactattt taaatccttg agactcataa cattttacag ctctcatgtt
     3181 ccaggttctt acatttaata caattggttt agtactatat ttatttctac attcttgtaa
     3241 tcctaggcta attatttctt taccaattcc cattccacaa taattcggtt tcataccaat
     3301 accaaagaat acagagcttc cttcatctaa taagcttata aaacctatca attctttatt
     3361 gtcatttata aaacttataa aattttttct tttatcttct tttgctagtg aaaaattatt
     3421 ctttttaatt tcctcccatg gaggtagatt gtatattgaa tatttacctt catatttcca
     3481 attagtaact tcaatagcat gttcttcagt aaatttaact ttatttaaat tcatatgtcc
     3541 tcctattaaa atatttaagg taattaatgg tattttaaag ttttagaaaa taagtaaaac
     3601 tatttatatt tatccataaa atctttaaaa attttactaa caattcttgt accctgtact
     3661 ttttattgga ttcacagaag actataaact aattttgaat taccttctaa ttcaaaaaca
     3721 tcacgatata tataatttct tagcttgatt aaattctgtt aaatccgttt cttatagttg
     3781 tataatcaac atcaatatct ttatgtgtat tagttaattt attggcttta ggaacttatt
     3841 attaatatat tatatttact ccaagtagta ggtaaattat aggcaaatta tcaaatgtat
     3901 atctatccat gcttaaactt tagagataca ataacta
//
LOCUS       DAEPXW010000187         3923 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.191, whole genome shotgun sequence.
ACCESSION   DAEPXW010000187 DAEPXW010000000
VERSION     DAEPXW010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3923
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.191"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            145..1650
                     /locus_tag="KRM55_003609"
     CDS             145..1650
                     /locus_tag="KRM55_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1595794.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            1764..2462
                     /locus_tag="KRM55_003610"
     CDS             1764..2462
                     /locus_tag="KRM55_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH1595795.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            2747..3835
                     /locus_tag="KRM55_003611"
     CDS             2747..3835
                     /locus_tag="KRM55_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595796.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
BASE COUNT         1544 a          391 c          634 g         1354 t
ORIGIN      
        1 ataaaaaaaa ataattaata taaaaatgtg tacaaactaa tgaatattga tatagtaagc
       61 tatcatatga aagagtatgt acacattttt tttactaatt tttcacaata tgaacataaa
      121 taatttacag gaaaggaatc ttttatgaaa attcaaaata ctgaatgggg atatattgaa
      181 tggaaacata cttatgatga aaataatcca aaacaagcta tgaatatata cattgcagta
      241 actatgcctg gtaagaaaca ttttaatcat gttcattatg gtcaagagca gatgatatat
      301 attttagagg gagagggttt gtatattata aatggagttt ggaagccatt ttatcaaggt
      361 atgatttttt atatagaatc tggtagcaca catgaaacta taaatacagg tgatagagaa
      421 ataaaagaac ttattgtttc aaataatgta gatgatgtag gagagagtga agttatagat
      481 attaatccta ataattattt aaagaagacc ttgataaatt atagtgaaag tacattaaat
      541 ttgtatgcag cagtagaatc aattcgtggt caatttatag acccgtttaa aattccatta
      601 attatatatg atgattcatg gaatatagtt ttaaaaaatc cttattttcc acttttttgt
      661 tttgaaaaat gtaatcctat gaaatttcct caaaattgtg attgtatgaa tcaaaaaagt
      721 agcaatcaat ttgtatgtga atatgggata actatatata atataccaat actgtacaaa
      781 agcaatagca taggtgttat aagaggaggg tatgtactat tatctgattt gaatttagat
      841 acagagcata ataatttata tgatattcca gagggagctg ctagaagtat aaaacgcctc
      901 ctgaaacaaa tatctaaaaa tataataaat ttttgctctt ttaatgatat aagaaaggat
      961 ttacaagaaa aagagaagac tatagcaaga acatatcatt atggagagca acttgaaatg
     1021 aatttaaaag tagctcaaga tatggttact aatttaagaa taaatcatca ctttttattt
     1081 aatacattaa attcaatggc aagcatagcg ctagatgatg gtagttatga tttgtatagt
     1141 gcaataatag atttatcaag aatgtttaga tatacaatga ggtctgattt aagatttgta
     1201 gaattagaat ctgaaatatt atacattaaa aattatttga atttacagaa attacgttat
     1261 ggagatgcac ttaaagtaaa atatcttatt ccagagaagt tatataacct ttctgtgcct
     1321 tttaacttta ttcaacctat tgtagagaat gcatttacac atggatttag agatattgac
     1381 acagaaaagc gaattgaaat aattgcaaga ttagattctc agtatgctat tatagagatt
     1441 cataataatg gaactatctt agatggaaat aatatagaca aaataaaggc aggtattcgt
     1501 agtaataatg gtcatggttt gtctttaata tatacaaaat tcacatctgc ttatggaaat
     1561 aattttgata tggatataaa gtcgagtgat aatgaaggaa cttacataat gattaaaatt
     1621 cctattgaaa attataagga atatgtatag aacttgtgaa aaattaataa gttttataaa
     1681 tgttaagaaa tatattagat gtttttatgt tgttttatat atcttacttt tttatattat
     1741 taagctaaaa gggaggtatt ctcatgagaa gagcactaat aatagatgat gaagaagctg
     1801 ttctaaaaat aataacacat tttatagaaa tgaaagatat gccaataaaa attgttggta
     1861 aagcaacatc tggtgatgaa gcagtagata aaatcattgg tttagagcca gacatagttt
     1921 ttatagatat tcaaatgcca atatacaacg ggttagaagt aatagaaaaa acatctcatt
     1981 tatctaaaaa aataaacttt gtagtaataa ctgcatttaa ctattttgaa tatgctcaaa
     2041 aagctttgag attaaatgta aaagatatac tccttaaacc attagatatg aaagaattta
     2101 ctaagtctgt agaaaaaatt attggatatc aatataccaa taatgattta ttaaatgaga
     2161 tactggaata tataaatcta aactatagca atgacttaaa gttaaatgat tgtgctagat
     2221 tatttttaac caatccatct aatatatcta ggatttttaa aagtaattta aatacaactt
     2281 ttatatcata tctaaatcat ataagaatag aaaaatctat tgagttactt gaaaatacta
     2341 caaaaagtat aaatgagatt gcagaaatag ttggatataa tagcctaaat aacttttata
     2401 aaaactttaa gatagaaaaa ggaatgactc caaaagttta taaactgaac actaaaaatt
     2461 gaaattgata aataaaaagt caatatagat aattgtttga gtgtgtctga ataagtatac
     2521 tttaattatg ataaaaatta aagcgcttta aacatattta ataatattaa accttataaa
     2581 agctgtacct atttatataa aaaaatatat ataaataaaa agaaaaagat atacaaaata
     2641 aaaaaagtga attaaatact gttttaaaaa tacagaattt tcatttaatt cactgagagt
     2701 ttatatttct taaaggaagg taactttata atggaggtaa tttaatatgt cagacaaagt
     2761 gaatatgaaa aatattatct gtattgcagg cgcttatcta gcaacagcaa ttggttctgg
     2821 gtttgctact ggtcaagaaa ttctacaatt ttttgcctca caagggtata tgggtttaat
     2881 tggagcatta atatcaatgg tattgttttc atttcttggt gctgaagtta taactagagg
     2941 tagagaatta aaacttaaag aaccaacaag aatttacact ttttattgtg ggaagatttt
     3001 aggaaaattt tacgaatggt ttagtccaat atttttattt gggattctta tagtaatgat
     3061 ttcaggtgca ggctcaactt taactgaata ctatggtata aatccttact taggaagagt
     3121 attgatggct gttgctactt taattacagt gtctatgggt ttagaaaaat tagtaagcat
     3181 acttggacgt attggaccag tgatagcagt atttacaatt gctgttggat taataagctt
     3241 gtttaagcat tttgacggtt tatctatggt tggagaagct atgaaaaata ttgaagttac
     3301 aaaagcatca gaaagtccaa tcgtttctgg tgtaatatat aatacattaa atattattgt
     3361 aatgattgtt tttttaacag gaatgggagc ttctattgaa agtaaaaagg atgctttttg
     3421 gggaggttta ttaggtggaa tagtgtttat gactgctggt atagttatgt atttggctat
     3481 gatttcagat ataggaaatt tgtatatgaa agaaatacca tcactttatt tagcagataa
     3541 tatatctccg attgtaggtg tatgtttttc agttgcatta atattaggta tctatacaac
     3601 agctgttcca cttttatggt ctgtaaccaa tagaattgtt gaagatgaac atcctaaatt
     3661 taaattggta acaacagtaa tagctatttt ggcttgtata ggaggttttt taccgtttgg
     3721 taaattagta aacattttat atccatatac aggttatatg gggcttttaa ttttagtctg
     3781 tatggtgtat aaagcaatta catgtagaaa aaaatcaaca caaagtcagg aatagagcca
     3841 cttattaata gtttttattt aaagaaattt tttatataat ccgaatttaa aaagtcaaaa
     3901 tagttaaata aattgcaaaa cat
//
LOCUS       DAEPXW010000188         3826 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.192, whole genome shotgun sequence.
ACCESSION   DAEPXW010000188 DAEPXW010000000
VERSION     DAEPXW010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3826
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.192"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            93..1568
                     /locus_tag="KRM55_003612"
     CDS             93..1568
                     /locus_tag="KRM55_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH1595797.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLENIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1655..2068
                     /gene="speD"
                     /locus_tag="KRM55_003613"
     CDS             1655..2068
                     /gene="speD"
                     /locus_tag="KRM55_003613"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBH1595798.1"
                     /translation="MKFETLGRHILVEYYNCDENILKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2098..2949
                     /gene="speE"
                     /locus_tag="KRM55_003614"
     CDS             2098..2949
                     /gene="speE"
                     /locus_tag="KRM55_003614"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBH1595799.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            2939..3817
                     /gene="speB"
                     /locus_tag="KRM55_003615"
     CDS             2939..3817
                     /gene="speB"
                     /locus_tag="KRM55_003615"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBH1595800.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNILNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
BASE COUNT         1508 a          418 c          704 g         1196 t
ORIGIN      
        1 atgagtttaa taaaagtaaa aataaaaaat agaaataata aataataaat attaaaaata
       61 tttgaatata gagaggagat gaatttgaaa tcatggatag cgagtttgca aatgcagttg
      121 aattaagcta tgagtgtgct ccattattag agtcgttaaa ggaatactca gagaaagata
      181 tagcttgttt tgatgtgcct ggacatgtaa aaaatagagg tgtagctata ttaaataaat
      241 atctaggtga aagtctcatg aaaatggata taaattcatc accaactatg gataatgtat
      301 ctgcgccaaa tgggattata aaaaatgcac aagatttgct agcacaagca tatatggctg
      361 atgaggcatt ctttataacg aatggcacaa ctcaagcaat acatgcaatg attttgagtg
      421 ttataaaacc aggtgaaaaa gtattacttc caagaaatat acataaatca gtaataaatg
      481 cgttaatact ttgtggagga ataccaatat ttatacaacc agaatttgat gaaaaactag
      541 gtataagttt aaatattact cttgaaaaag ttagaacaga gatagaaaaa gattgtaata
      601 taaaagcatt atttttcctt aatccaactt actatggagt ttgtgcagac cttgagaata
      661 ttatagaact atgccataaa aataatgttt tagtgttagt tgatgaagct catggtgcac
      721 attttccatt tcatttagat ttacctcctt ctgcaataag tttgggagct gatatggtag
      781 ctgtaagtat acataaaact ggaggagcat tgacacaatc ttcagcactc ttattgaata
      841 gagataatgt aagttttgaa aaggttcttc aatcaatcaa tatgctacaa tcaacatcag
      901 catcttattt gcttatggca agtatagatg gtgctagagt taatctagtt gagaatggtg
      961 aaaagcaatt gtcaaaagca ttaaatctat ctaggtatgc aaaatctaaa ttgaacaaaa
     1021 ttgatggaat aaaagtttta tctacagaaa tattgaaaca aaaaggtgtt aaatttatag
     1081 atgaaacaaa attgtgtata aatgtaaaag aattaaattt gactggattt gaagtatacg
     1141 atttattata taaaaatttt tcaattcaag tagaattggg agattcatat aatatactgg
     1201 cacttgtgtc cattggaaca aataaatcag atatagatag attagtaaaa gcactttcta
     1261 taattgcaaa gatttataga aaagaatcaa cattaaatga atttaatatg gttcaaataa
     1321 atccaattat taaacttaat ccaagagaag ctttttatgc accaaaggaa agtgtagaaa
     1381 tcaattcatg tatagataga atttgtggag aatcaataat ggcatatcca ccaggtatac
     1441 cgattattgc tccaggagaa ttgataacag aagaaattat ggagtatatt attttcttaa
     1501 aaaatagcaa tgcgtatctt acagatgtac aagataaaaa cttagataga atactagtaa
     1561 taaaataaat tactttattt tgcaagggca agtgtttgtt aagtagagtt tatcaaatag
     1621 aacttattaa aagtataaag gagttggggt tgaaatgaaa tttgaaacac taggaagaca
     1681 tatactagta gaatactata attgtgatga aaacatactt aaagacccac gtcttataga
     1741 aaattttatg aatgattcag cattaaatgc aaaagcgaca attgtggatt ctgtattcca
     1801 ccattttaat ccttgggggg tttcaggagc tgttataatt gctgaatctc atttgacaat
     1861 acatacatgg ccggaatatg gttatgcagc agcagatttt tttacttgtg gtgatataga
     1921 cccatggaaa agttttgaat tattagagca acttttaaag tctgaaagaa gcgagtctac
     1981 agaaattcca agaggcttaa ctacaaaaat taaaaaatat tcaaaaaaag atttaggtaa
     2041 gattactcat aaaccagaag cagtataaaa catacaagag aaagtgagga ttattatatg
     2101 gaactttggt atacagaaga atggacagaa aatgtaagat tttctataaa agtaaataaa
     2161 catctatttg aaggaaagtc tcaatttcaa aggatagatg tgtttgatag tgatgaattt
     2221 ggaaaatttc taacaataga tggattaatg atggtaacat ataaagatga atttatatac
     2281 catgagatga taactcatgt tcctatggct acaaatttaa acataaagaa agtattagtc
     2341 ataggtggag gtgatggagg tacagtaaga gaattaagcc gttatcctca aatagaaaag
     2401 attgacatgg ttgaaataga taaaatggtt gtagatgtat ctaaggagta tatggatata
     2461 tgctcatgta aattagatga taaaagagtg agtttatatt ttgaagatgg tgttaatttt
     2521 gttaagtgtg cacatgataa atcatatgac ctgataatag tagattcaac tgacccaata
     2581 ggaccaggcg aagggctttt ctcaactgat ttttataagg attgttatag aatactgact
     2641 gacgatggaa ttttagtaaa tcaaagtgaa agtccgtatt ttgactttaa tgctaaagag
     2701 atgaaaagag ctaataaaaa attaaaacag atatttccaa tatcagaagt ttatcaagca
     2761 catataccaa catatccatc tggtcactgg ttgtttggat ttgcttcaaa aaaacttaat
     2821 ccagtaaaaa atcaagatag aaatggatgg gagaaattaa gtttaaaaac taaatattat
     2881 aatagtgata tacatttagg ttcgtttatg ttacctcaat acgtgaagga gatgctagat
     2941 gaagaataat ttctatcata tgaacacttt tatgagtatg gacaaaaatt atgaagaatc
     3001 taatcttata gtatttggtg ttggatttga tggaactact tctaacagac ctggggctag
     3061 atttgcaagt agctctatga gaaaagaatt ttacggtctt gagacatata gtcctttttt
     3121 agatttggat ttagaggatt ataatatatg tgattatgga gatttagaaa ttagtgttgg
     3181 aagtacagaa caagtcttaa aagaaatcta tcaagagaca tataagattg ttagagattc
     3241 aaaggtaccc tttatgattg gaggagagca tttagttaca ttaccagcct ttaaagcagt
     3301 acatgaaaag tataatgata tatatgtaat tcattttgat gcccatactg atttgaggga
     3361 agaatataat aatagtaaaa attctcatgc aacagtaatt aaaagaatat gggatattgt
     3421 aggtgataat aaaatatttc aatttggtat aaggtctggg acaaaagaag aatttaaatt
     3481 tgctacagaa gaaaaacaca catacatgga aataggagga atagatacgt ttgaaaatat
     3541 agttaatata ctaaatggaa agaatattta tctaactata gatttagatg tattggatgc
     3601 atctgtgttt ccaggaacag gtacaccaga acctggtggt gtaaattata gagagtttca
     3661 agagattttt aagattataa aaaactctaa tataaatata gttggttgtg acattgtaga
     3721 gttaagccct gattacgata caacaggtgt atcgacagtt atagcttgta aaatcttaag
     3781 agagttatgc ttaataatat ctgataaaat taaatagagt atttta
//
LOCUS       DAEPXW010000189         3785 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.193, whole genome shotgun sequence.
ACCESSION   DAEPXW010000189 DAEPXW010000000
VERSION     DAEPXW010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3785
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.193"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(226..1476)
                     /locus_tag="KRM55_003616"
     CDS             complement(226..1476)
                     /locus_tag="KRM55_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBH1595801.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1508..2449)
                     /locus_tag="KRM55_003617"
     CDS             complement(1508..2449)
                     /locus_tag="KRM55_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBH1595802.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            2683..2940
                     /locus_tag="KRM55_003618"
     CDS             2683..2940
                     /locus_tag="KRM55_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595803.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(3050..3730)
                     /locus_tag="KRM55_003619"
     CDS             complement(3050..3730)
                     /locus_tag="KRM55_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH1595804.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYLIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
BASE COUNT         1265 a          642 c          377 g         1501 t
ORIGIN      
        1 aatacacatt taaaacctta taaatataca aatacaatta tatgaatttt catcctcaat
       61 tatagcatag aatatgacta tctatatcct aaaattatcc atttctaaaa aaaaggtaac
      121 tattattaag aatatcaact tatagaattt atattccaca tacgattttc aatcaaaaaa
      181 acaagggcta aaaagtgaat tgtgcacttt ttagcccttt attaattatt catttatttc
      241 atgtaagaat agaccacatc ttactttagg ttcaaaccat gttgacttag ctggcattat
      301 cttatttgca tctgctactc ttattaaatc ttcaatacta gtaggataca ttgcaaatgc
      361 tactttcata tcttcattaa ctcttttttc taattcttca agacctctaa ttccaccgat
      421 aaaatcaatt cttttatcta ctctaggatt atcaattcct aaaatagcat caataacata
      481 gtcttgtaat atagaaatgt ctaatgagtc aacagggtct tctatttcta ataaattttt
      541 atttgctttc attttatacc acttatcacc taggtacatt ccgaaagttc cttttttgtc
      601 aggtttatat ttttcttttc cttctatttc ttctagttca aaattttctt ttattttatt
      661 tataaattct tcctcgctta aaccatttaa gtctttgata accctattat aatccaaaac
      721 cattaaattc tcatctggtg caatcattgc tatgaagtaa ttaaattctt cttttccagt
      781 ataatttgga tttttagctc tcatttcttt ggctacattt tctgctgaag ctgtcctatg
      841 atgaccatct gcaatgtata gataatctaa tttttcaaat ttatctacta ggttatctat
      901 tatatcatca ttatcaatct tccatactgt atgctctatc ttgtcatctg ttatgaaatc
      961 atataaaggt tcattattat ccataaaatc attgattata tcatctatca ccctttgatg
     1021 tttgtaagtt acaagtatag ttcccgtatt agcatcacag tattttatgt gtttagttct
     1081 atcaatttcc ttttctggtc gagtgtactc atgttttttt attgttccat tcaagctttc
     1141 atcaactgat atacatgcta ctataccaac ttgagctcta ccatccatga tttgtttata
     1201 tatatatata cactctttgt catcttttac tagaatttct tgttttcgaa actcatctaa
     1261 attttctcgc gcttttaaat aaactttttc atcatataaa tctatatttt catctaaatc
     1321 aatttctgat ttatctatat gcaaaaatga atatggattc ccttctgcaa ttcttctagc
     1381 ttctttacta ttcataacat cgtaaggaag tgctgctact ttatctacta tatatttatt
     1441 tggtctaatc gccttaaatg gtttaatcgt tgccattact aatttcctcc taattataca
     1501 aaatatttta taatgctacc cctattagat tgttgaagtc aagaaagaaa tcttgaatca
     1561 catttactat ttcgtctcct attctttctt gagcttctac tgtagatgcc ccaatatgag
     1621 gtgtaggaga aactcttgga tgatttacta agtctaaatt taatgtaggt tcttgttcat
     1681 aaacatctat agcagctgct gataatttac cttcatctaa tgcttttagt aaatcttttt
     1741 catcaactaa accgcctctt gcacagttta ttaaataagc ccctttcttc atcttattta
     1801 tttctttttc agttattact gcccccttat tcttatcaaa tggtatgtgt aaagataaga
     1861 aatctgcatt ttctaaaact tcttccatat cacagaattt ataattgtta aagccttgcg
     1921 cctcacccat tatgtcagta tatataacat tcatacctaa taattctgct ctctttgcaa
     1981 cttcttttgc aattcttcca aaacctataa gtccaagtgt ctttccatta atttctgtac
     2041 ctttatactt tttcttctcc cattttccat ctctcatagt tacatttgca gtatttatga
     2101 atcttgcaag aacaaataat tgacctattg taagctctgc aacagatata ctgcttgcat
     2161 ttggagtatt cataactttt atgccattag cttgagcata tttaacatct atattatcca
     2221 gacctactcc acctcttact atcaacttca actttttacc ctctaatgct ttatctatta
     2281 catctttagt aactttagta gctgaacgta ctacaagtac atcaacatct ttaagtttat
     2341 ctcctaaaac atctttttca taaaactgct ctatcacatt aaaatctaac tctctcaatt
     2401 ttctcgctgc ttctttctct attccatcag taactaatat attatacata acaaactcct
     2461 ccaattttta ttcacttaat ttttccaatt tttatttttt aaagtatttt catcaataaa
     2521 aaactttact taattcaact ttctgtttat ataattttca aaatattttt ttattaaagt
     2581 catgtcaaat ttttctattg tttgttaaaa atttaatatg taatttttat aaaatattat
     2641 ttattagaaa ttaaaatgaa ttaagtaaat ggaggaattg atatgataat aattagaagt
     2701 caagataaaa ctaatttaat gcagataaac caaattaaaa tagatggtag tcaagtttat
     2761 gcagtatttg aaagtaaaat tgatactgta aaaataggag attatgaaaa taatacaaga
     2821 gctatacaag tgttggacaa tatacaaaac ttcattgaaa atggaacaaa atatgattat
     2881 ataacatcaa ataaagtcag atacaatgtt aataaaatat ttcagatgcc agctaaatag
     2941 tgagtgtgca ttttaattta ataactaaag cccactttct tttgtagtat gaaagagggc
     3001 tttacatatt tgtaaatatc gaagtacact tattttatca ataaattatt taataaggta
     3061 taatggacca attaaacaat aaaaattctc ctaaaacagc aagtattaaa tatataatag
     3121 cttcattttt gtaaagagag gtaatttttt tgcttatgtc atcatcaatt gtaatagcaa
     3181 tctcatcttg aataatattt ttatatatag atgggaaaat atcttttttc tttataagat
     3241 taaataaatt atttacacct acccatataa gatatcctaa aacagcacct aatgtgttca
     3301 tcattaaatc atcaatatct gtagctctta agttaaacaa ttgacaaagt tcaattgcta
     3361 atgaaaaacc taatccagtt aatgaaacat tgataatatt tctaaaattt ttccaaatta
     3421 aaggtagtaa aaatcctaaa ggcataaaca taattatatt taaaatatat gttaagatgc
     3481 caactgagtc aaaaggtatt agatttattt catcaattct aaaaagccca ctataccttc
     3541 ctatatccca tatgctacca attccagctt tactaagtgc tagatagata tataataaaa
     3601 aaatatatac ccatactaaa tgtatcatta cattcttttc aactttcaaa ttttttcgtt
     3661 ttataacgac tatttggtat attaagcatg gtaatataac gcaaataaat gaataaaatg
     3721 tccatatcat tttattttgt cccctttcaa atttatgttt ttagttttat aagtactatc
     3781 tttat
//
LOCUS       DAEPXW010000190         3654 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.194, whole genome shotgun sequence.
ACCESSION   DAEPXW010000190 DAEPXW010000000
VERSION     DAEPXW010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3654
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.194"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(274..1290)
                     /locus_tag="KRM55_003620"
     CDS             complement(274..1290)
                     /locus_tag="KRM55_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1595805.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            complement(1473..1835)
                     /gene="spoVAE"
                     /locus_tag="KRM55_003621"
     CDS             complement(1473..1835)
                     /gene="spoVAE"
                     /locus_tag="KRM55_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBH1595806.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            complement(1849..2862)
                     /gene="spoVAD"
                     /locus_tag="KRM55_003622"
     CDS             complement(1849..2862)
                     /gene="spoVAD"
                     /locus_tag="KRM55_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBH1595807.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            complement(3029..3466)
                     /gene="spoVAC"
                     /locus_tag="KRM55_003623"
     CDS             complement(3029..3466)
                     /gene="spoVAC"
                     /locus_tag="KRM55_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBH1595808.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
BASE COUNT         1188 a          645 c          388 g         1433 t
ORIGIN      
        1 tcatttttat atacttttag ttatgaatca aaaaaatatt atagattcat gatataaaat
       61 acaaataatt tattaattta tattgttaaa ataacggatt ttcaaataat tgaataaaat
      121 tattcattca tattataaaa actatctcaa taaataaagg agtacaatgt acttatatac
      181 acctactcct tttaattttt atttatatta tttgttaaaa aacttcacat aatctataat
      241 atttttaata aacgtttgat acttaaaagc ttactacttt attcttttaa cgctatttcg
      301 tattattaac cttggatata attttcttgg aatgtgttct gtactctttt tatttattat
      361 atttactaaa ctatctactc cattttttat aacttgctct cttgggtcat ctattgttga
      421 taaatgcgac ctaaaatatg atattaattc aatattatta taccctatta tggaaatatc
      481 ttctggtaca tttataccat aagtagtttt taactcttgt attatagaaa tcgctggtac
      541 atcttgttgt acaaatatag ctgaagcttt ttttatttta tcaatgtatt tttctaaaaa
      601 ttcaacttga gattcaaaat ccattttaga tttaatgact tctgtcttta aatttgcctc
      661 ttccatagca ttcaaatatc ccttggttct atcttcatgc atttttgaac tcttatcatc
      721 tgaagttact gttattatat ctttatgacc atggtcaatt aaatgcttgg tagctatata
      781 acctccatac acgttatcgt cccaaaagaa attgtctact tctcctataa aagatggttt
      841 aaaatatata aatacatgtg gaaaattatt gtcttttaaa aaatcatact cttctttttt
      901 tattgattga gacacaatta ctaatccgtc aaccatttgt ccatttacca ttttatatac
      961 attactatca ccactaatgt tattattagg ctgtattata aaatcgtatt tattagtctc
     1021 aatagaattt atagaactat ccattatatc actaaaaaac tttctagtat cttgatgatt
     1081 aaaattattt gaaaagatta cccctatcct gttagtttct ttttttgcta aatttcttgc
     1141 atttacatta aaatggaacc ctagtctatt tgcctcttct accactttct tttttgtttt
     1201 ttcagataca ttaggattat tgtttaagca cctagaaaca gttgaataac tgatacctag
     1261 attccttgca atatctttaa tagttaccat ctttatcccc tacttcactt cattttattt
     1321 tgataatata atactacact atgttgtaaa taattgtcaa cttcaattat gtaaacgctt
     1381 ctttatataa aaaataggtg gaatctaaaa gatatccacc tgctttataa aaagttatta
     1441 tttcaaaaac ttattattct tttaataaag atttatggtt ttgcttttgg agtaaatact
     1501 actgacataa tatatccaaa gaatatagct gctgctattc caccagctgt agcagttgta
     1561 cctcctaaaa aaatacctaa aaaaccatca ctttgaattg attttattac tcctgtagca
     1621 agtgaatatc caaatcctat tataggaact gttgcacctg ctgctgcaaa cttaactaat
     1681 ggctcataaa gtcctagaaa agttaaaact acaccagttg ttacatacgt taccataaca
     1741 tatggagttt gcattttgaa ataatccatc attacttggg ctattaaaca tataattcca
     1801 cctacaataa atactcttac atagtccatt aacatattat atcacttcct actcatttac
     1861 tattactact gcatgtgcaa cacatggtat tgtctgcttt tgtagtgtac ttgtcggtga
     1921 aagtagtgct cctgttgata caagcattac tttgttaaat tctttttttc tcaacttatc
     1981 atatatatat cctgcaaaca ctgtagctga acacccacat ccacttccac cacagtggac
     2041 atcttgttct ttaaggttaa acatctctat accacagtca gtataaactt ttgatatatc
     2101 tacacctttt tcttttagaa agtcttctgc tatctgtttt ccaagagtac ctaaatctcc
     2161 agtagcaatt atatcaaagc tatttgggtc atcattagta tcttcaaagt aagagtagat
     2221 agtatctatt gctgctggag ccatagctgg tcccatatta ttaccatcat caataccctc
     2281 atctattact ttaccaacag taacatactt tacttttgga ccgtctccat taggagctaa
     2341 taatacactt cctgctcctg taactgtcca ctgggctgtc attggttttt gatttccaag
     2401 ttcaagtggg aatctaaatt gtctttctgc tgtacaatag tgacttgatg tacctgacag
     2461 tactaaatca gcaaaaccac catctataag catagaacct atacaaagac cttctgccat
     2521 tgtagaacaa gctccatata tacctaaaaa tggaatagcc agttctcttg ctgcaaatga
     2581 tgctggaact atttgattta ttaaatcgcc acctagcata taatttacat ctgacaattt
     2641 tttacctgcc ttttggatag cttgttgaga tgcagtctct accattttac tttcagctaa
     2701 ttcccaagtc ttttcaccat ataaatcgtc agtcataatc atatcaaaat agtcctttag
     2761 tggtccttca ccttccttag gacctactat agttccagtt gatattatgg ttggtttatt
     2821 ttctaacttg actgttcttt ttccaattct tttatttttc atattttcac acctttttaa
     2881 ttttgcattt tactattcaa atttttaata ttaattaaaa attttaatta aatctgcaca
     2941 attatttttc aattagttac tttagtagct attttcagat tttatacctt cttcataatt
     3001 aataaaattt aaattaaata aaaatcatct aaaacatctt aaaaatataa taaataattc
     3061 cacataaaat agaagaacct ataccataaa ctaaaactgg tcctgcaatt ttaaataagt
     3121 ttgcacctac acctaataca tagccttctc ttttatactc cattgctgga gatactattg
     3181 agttagcaaa acctgttatt ggaattatag aaccagctcc agctcttttt cctattaggt
     3241 cgtaaactcc taatccagtt aaaaatgccc ctataaatat taatgttatt gatgttgcag
     3301 aactagcacc tagtttatca agacctccaa ctttcatata caaatcattt attgcttgcc
     3361 ctatcataca aataattcca cctacaataa atgcaagtgt atagtttttt aaatatgtag
     3421 gttttgggct tatttgatct acatattttt tataattttt atccatacta aacacctctc
     3481 taaagtatta tttgttaatt ttaaaaaaat aaacctatta tttattttga ctatctaaag
     3541 tttggtcaaa aaataaaaaa gatgcctaat aaagaaaaaa tctatttttc cataaagaca
     3601 ccttgttttt atatttttac ttttttaatg ctttttatta ttttaatatc tttt
//
LOCUS       DAEPXW010000191         3649 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.195, whole genome shotgun sequence.
ACCESSION   DAEPXW010000191 DAEPXW010000000
VERSION     DAEPXW010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3649
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.195"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(66..509)
                     /locus_tag="KRM55_003624"
     CDS             complement(66..509)
                     /locus_tag="KRM55_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595809.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(512..709)
                     /locus_tag="KRM55_003625"
     CDS             complement(512..709)
                     /locus_tag="KRM55_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595810.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(901..1767)
                     /locus_tag="KRM55_003626"
     CDS             complement(901..1767)
                     /locus_tag="KRM55_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1595811.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(1993..2862)
                     /locus_tag="KRM55_003627"
     CDS             complement(1993..2862)
                     /locus_tag="KRM55_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1595812.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVATDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(3368..3589)
                     /locus_tag="KRM55_003628"
     CDS             complement(3368..3589)
                     /locus_tag="KRM55_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595813.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
BASE COUNT         1247 a          639 c          347 g         1416 t
ORIGIN      
        1 tcttctagca ttaatttaaa aactaattta tttttatata attttctatt ttatatcata
       61 acttattaca actttttatc taatttattg tatacaacaa cactacaaat aaattgaaat
      121 aaaataagca atccaagaac aactaaaacc cacttgctta ttaccattac agaaaataca
      181 ctcaatatag aaacaataaa tataagaatt acaagaacat aggacatgat ttgattagtg
      241 atacgtccag ctttatcacg taacataatt cttctttcat cattcatctc tatcctttga
      301 ttttttatct tttcttcata atctactgct ctttcaggtt tactccaata catatattga
      361 agaatcatac atacacctgg acctaaagca gctccagata atccccaaat aaaagcctca
      421 aatgaaaact cagtaaatgt agccaataaa acaagtaaaa ttccacaaat aaaatatata
      481 attccaacat ataacatatt ctttttcatt tttactcctc ctcataaata aatatttctt
      541 caatactcat atcaaagtat ctagctatct taaaggctaa gatgatagaa ggattatacc
      601 taccattttc taatgaacct atagtttgtc ttgatacttg caaaatagaa gcaagttctt
      661 cttgttttat gcctctttct tttcttattt cttctaatct atttttcaca tctatccccc
      721 tttaatatct caactacgga aagtctactt tccataatta tacaactata ttccatttat
      781 gtaaagctta ctttccatat ttacaaaaaa ataacagact attttcagcc tgtaatttta
      841 gaatttcatg ttgtttatta attttaatgt tatttattaa ttccatatta tttattaatt
      901 ttaacttggt ttctgaattg gaatccaaac ttctgtagta taatcaggag cattgatatc
      961 gccattggga taaagttcaa tatctggtaa attagcatac acatacccag aacttggtaa
     1021 ccactcagta ataattcttt tttgcaattc ctgtattgcc agagcatttg gcattggaga
     1081 aacacattca aatactgccc atgtgcctga tggtattaag tattcatgag tatcttctaa
     1141 tacaggctta tctgttggag cagcaatata ataatctaaa cccttactat ttgtacacac
     1201 actaactcca agcaatccac aaggttcatt atttattaac tctgaaagtt tatcaattgt
     1261 tccatttttt atgcatttag cccacaactt aggaactttc tcaaagcact cttctacaat
     1321 catgttcata ctttctttta taccaacaat acgaaaccct ttcttttcta caatacgata
     1381 ttgcatttct atatttcctt ttacataaat gcttaatgtc atcttaggat atgcttttaa
     1441 aacaacaccc tttgctctag ctgcagatgg agaaatgtta tgtatatttt gaaaagctct
     1501 attaaaagat gttggtgaat cgtaaccata cttctcagat agttctaaaa ttttgatgtt
     1561 actgttctga agttcaaatg cagccttagt catacgtctt cgtctaatat attcagataa
     1621 tggtacttct gcaatatatg aaaacattct ttgaaaatga aaggttgaac aacatgcaat
     1681 ttttgctgct tctgcataat ccactccact ttcgagattt tcttcaatat aagtaatagc
     1741 ttgatttaat ttatttatcc attccatttg atattacctc caagcaaatt atacagttta
     1801 ataaaataat atacctctct attcatgcac aaaattgtaa gcatttaaat tcataagtat
     1861 ttttcaatca atacaataaa tataaaaatt gtattataca ataaaaaagt tcaataacat
     1921 tatattataa aatgttattg aactttttat aaaaattaat ttaagtgtag ttaaattaag
     1981 tattacacta tcttatatat tacaatatcc tactatctta tagtcttctg gcactttata
     2041 atctttgtct ggagtaccta aattccattt taaatcaaac atagttgcac ttattattgt
     2101 tgcaaaataa agcataacta taccaatgtc tattttttct tcatataaat tagtatgacc
     2161 atcttttcta acagctaaaa ctacagtgcc tccatcaact ataaatctcc atggttgtct
     2221 atttaatgta gatggagcta atcttgcata gtgaaatgca tcaagaagtg ctctttcttc
     2281 taagatttct atacttgcaa catttcccca ttcgttcata taaacaacat cttctacacc
     2341 tagtctagta gaccccttat ctgttgcaac ttgcatatca gattttgaat aattttgccc
     2401 agtttttgta gcatttaata ctttagcatt acttacattt tctccatatc caatagctat
     2461 aattcctgtt acctctttat ctgaattaat tccaagtttt tcttttacct tttttccatc
     2521 ttcaaaagta acccaacaag aaccaattcc aagttctgtt actttaaaga ttatactttc
     2581 tcctatgtac cctgaatttt caatgtaatt atcttttatg tcagataata ttataatata
     2641 acttggagaa tctatcatat ttcctttgta ccctgctact ttatctaaat tattaaaaac
     2701 ttcacttcta ttcataattc ttacatcaac atctatttct ggaactagtt tcttacaaga
     2761 ttctgagtat ttcttaattt cactaagata ttcttcttta atatctgtgt tcttatattc
     2821 tctaacagac tttctattta atatgattgt tttataatcc ataattttat cctccccaaa
     2881 ctagtattgt cttaattata tacccattaa tatattattt tactcattta tttaataaat
     2941 aaagattaca attttgtaat tattatttat taataatatt ccacttttac attaataatg
     3001 accagttgtg caaaatccat tgccaaccac caaataaaaa catattataa aggtaatata
     3061 aaataacaaa caaatcttaa caaaaaatta aacttttttt acacgaaaga aggcttcccg
     3121 ttgccttctt tatttttata aaaaaataag ctgtttctaa aatgatttca catttttgaa
     3181 acagccaagt tattctataa tgacaactat aatttgagga tgtgagggag agttgtcatt
     3241 ataaatttag ggtaattata ttatgtttta agctagttct ttctatattt atataataca
     3301 ttttatatat gaattttata tgagattggt ataaatgata tatgaaatta catatgttta
     3361 tattatatta aattttatta ttacattttc cacaacaata ctcatatgtc tccacattat
     3421 ttggaatatt tacaaataca aattctttac agttctcaca atactttaat atagatatag
     3481 ttccacaagt gtaacattca aatattacac aatcctcatt ttcctctact atttcaaact
     3541 ttttactatg ttcaccacac tctgggcact tgtgattatt tacattcata aatactcctc
     3601 cttattagta tagttacatg tcaaaaactt aattaatgta ttctatatt
//
LOCUS       DAEPXW010000192         3584 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.196, whole genome shotgun sequence.
ACCESSION   DAEPXW010000192 DAEPXW010000000
VERSION     DAEPXW010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3584
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.196"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            34..687
                     /locus_tag="KRM55_003629"
     CDS             34..687
                     /locus_tag="KRM55_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1595814.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            828..2099
                     /gene="brnQ"
                     /locus_tag="KRM55_003630"
     CDS             828..2099
                     /gene="brnQ"
                     /locus_tag="KRM55_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH1595815.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            2301..3488
                     /locus_tag="KRM55_003631"
     CDS             2301..3488
                     /locus_tag="KRM55_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBH1595816.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISATMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
BASE COUNT         1313 a          395 c          662 g         1214 t
ORIGIN      
        1 tcaaaaataa tataatttat agtggagggg aaaatgacta aaattattaa agtgcaaaaa
       61 cctaaattta caggagaatt agaaattatt gaaaatcttg aagatatact tgaagatata
      121 tttaatgatg aaaaaatatt taataaaatt atagaaaatg aagttataag tgatttagat
      181 tctgtaagag ttagctttga atcttgtata tttagaaatg tgtcttttga aaattgtaat
      241 ttaaaaaaga ttgatttact tgatgtggta tttgaaaact gcaatttatc aaatacattt
      301 tttgatggag gaagtatata cagagttgaa tttaaaaata gtaaattgat aggagttaga
      361 tttgatgatt gtatacttaa aaacgttttg ttcaaggatg ttttaggtaa gtattctaac
      421 ttttcattct ctaaatttaa gatagtttct atcttagatt caaattttga aaattctgta
      481 tttcaagaag taaaaggtga caatctagta tttgagtata caaatttaaa aaaagcaaac
      541 tttaatggaa ctaaactttc tggcatagat tttactacta ataatattga gggaattgag
      601 attggtatag atgatattag aggagcaatt tttgatgtgt cacaagcaat tgatttaacg
      661 aaattgatgg gaattatcat aaaatgaaaa aaatattcat aaaataaatt gggaaaacgt
      721 taacaatgtg tgaattttta ccagattgac atttttctga aaataaagta agattatctt
      781 aatattcaaa atattttcaa agggggtaat ttagtgtgag taagcagatg agagatattt
      841 ttatagttgg ttttgcttta ttttctatgt tctttggtgc aggaaatctt atgtttcctc
      901 catttttagg gatggaatcc ggcaaagact ggttaattcc tcttattgga tttgttgttg
      961 cagatgctgg tatagcaatg cttgttatta tagcaacagc aagatgtaag ggaagcatgg
     1021 atgatgtact taggagagct ggtaaagggt tagcaagagt aatgagtgta gctgctctag
     1081 catgtttagc acttcttgta ataccaagaa cttgcgcaac aacatatgaa atgggtatta
     1141 tgcctatatt tggagaccat ggtccagtag ctaaagctgt attttcaata atcttctttg
     1201 ggctaacttt agcatttact attaggtctt ctaaggttat agacataata ggtaagtatt
     1261 taactccagc gttattatta gtattatttg ttttaatagt aaagggtata atttctccag
     1321 caggacctat gagtcctgag catatgatag ataaaaatct atttggtgaa ggtatatcac
     1381 aaggttatca aacaatggac gctctaggtg cagcatctat ggcaactata atgttgatgt
     1441 ctataatagc taaaggatat acatcagata aagaccaaat aggaatgact attaaagctg
     1501 gttttgtagc ctgtgtattt ctagcagtag tatatggtgg tcttacttat ttaggtgcaa
     1561 cagtttcaac tttatatgat actagtatac ctcaagcatc tttattagtt gaaataacta
     1621 gtatattgtt atatggtcaa gtaggaaagg taattttagg tgtaattgtg gcacttgcct
     1681 gtctgactac ttctacaggt ttaacagcat caatatcaac ttattttgaa ggaataagta
     1741 aggcgagtta taaacaactg gttataggta tatgtgtagc tagtatgctt atatcaaatt
     1801 taggtgttga ttctataata gccatatcag ttccaatcct acaaactata tatcctgttt
     1861 tattagcaat agttgttatg gagttggctg gtaaacatat aaagaatgat aatgctttta
     1921 aaggtgcagc atatgttaca ttagtgatta gtttattatc agctataaat ggaatgacag
     1981 gagctgttcc atttatacaa agcttgccac ttgcaggttt gggctttaac tgggtaatac
     2041 cagctatatt gggtggaata gttggtaact ttataaaaag caacaaacaa gtagcataat
     2101 aatttgtaat taatttaatt ttataatata ttaattttta gtactatggg taggtttaat
     2161 ctaaacctaa tctacccata gtacttttta gattggatta taatagcatg tatataattt
     2221 tttataatat aatttttctt tgaagtatga taaaattagt aatagtgata agaatgtaca
     2281 aatttaggag gttttaatta atgcttagaa aaataacagc atttatgcta tccatatgtt
     2341 taattattgg acttacaggt tgtagtttac ttgtaggcaa gaaagataaa gagaaaatta
     2401 tagatgattt taaagttgca gtggtaactc aaccattatc tgaaaataaa gtacaataca
     2461 atatggtgga agagatggca aaagaatatg aggaagagaa taaaattgat aaagacaaag
     2521 atggtcaaac taaagttaaa caaactataa agcatgttgt attgccagag aattttactt
     2581 ctaatataga cagtgctatt aataagatag taaagttggc tgacgataaa gaagttcagg
     2641 ctattgtagt ttcaactgac caagcagggc ttttacctgc tttacaaaag gtaaaggaaa
     2701 agcgtccaga aataataact atttctgcca ctatgggaga tgataaaaac caattaagcc
     2761 aatttgttga tgtgaatcta ggggttagtg cagaggaaag aggaaaagta ttagctgaac
     2821 gttcaaaaga aatgggagca aaagctttta ttcattatgc ctctacagat gatttgaaag
     2881 atgttaatat agccaaaaga ttagaaatga ttaaagagac ttgcaaaaat ataggattgc
     2941 catttgtaca agttaatact ccaaatataa atactgaaga agacaaaaac aaagttaagc
     3001 agtttttaaa tgaagatatt gaaaaacaag ttaaaaaata tggaaaagat ataaatgtat
     3061 ttggtgtaaa tgagtatatg gatgaagtta tattgactaa ggctttagaa ttaaagtata
     3121 tagttgcaga gcaaagcaat ccatcaccaa tacaaacata tcctagtgtt atgggtctaa
     3181 aaatatctga aaaagatgct caaaattatg ataaaataaa cgacatgata agtgaaaagg
     3241 ctaaggcttt tggcatgtca aatagacttg gtggatatcc tatgccaatg gatgcttttc
     3301 taccatcagt agcaatttat cttgctactg aaatggtgaa acaagattta acacaagaag
     3361 atgtatgtga cccagattat ttagaggcgt ttacagaatt aagatttgga atcggttcag
     3421 aatttactcc tttaacagag gtactttata attatcaatc agtaatttta agccaattaa
     3481 tttattaata ttaaggacgt gtctcaaaat gaacttttta gtttatgagg cactcttttt
     3541 ctgttaaatc aaatatattt ttatcttttt aacaattaaa aaga
//
LOCUS       DAEPXW010000193         3565 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.197, whole genome shotgun sequence.
ACCESSION   DAEPXW010000193 DAEPXW010000000
VERSION     DAEPXW010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3565
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.197"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..248
                     /locus_tag="KRM55_003632"
     CDS             <1..248
                     /locus_tag="KRM55_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595817.1"
                     /translation="FKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIV
                     IIAFLATGNLNISLKKNKCKASTKNKSEKRGVVDVTN"
     gene            235..990
                     /locus_tag="KRM55_003633"
     CDS             235..990
                     /locus_tag="KRM55_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1595818.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKEDLTVEEILEKFEYAV"
     gene            1087..2124
                     /locus_tag="KRM55_003634"
     CDS             1087..2124
                     /locus_tag="KRM55_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1595819.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
     gene            2933..>3565
                     /locus_tag="KRM55_003635"
     CDS             2933..>3565
                     /locus_tag="KRM55_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595820.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIA"
BASE COUNT         1334 a          467 c          543 g         1221 t
ORIGIN      
        1 tatttaagaa atttactttt atcaaagata ctactgcaat aattgttggc tcttttatat
       61 accaattcac tatatacttt gcaatgagtt taggaatgtt atcaactgac ttaaaactaa
      121 taactgccat agttataata gctttcctag ctactggtaa cttaaatatt tcactaaaaa
      181 aaaacaaatg caaagctagt accaaaaata aatcagaaaa aagaggtgtt gtagatgtta
      241 caaattaaaa atctttcaaa gagtttccct aatccatatg gtgaacctaa tactatcttt
      301 gaaaatttat caatcgatat agaagatggt gaatttgtaa gtatcatagg tagtaatgga
      361 actggtaaat ctactttatt aaatataata tctgggctta taaaagaatc ttctggtcaa
      421 attactttag atagtactac tataacaaat ttagctgagt ataaaagaac tcaaatagta
      481 agtagagttt ttcaagaccc aagccttgga acttgtcctt ctatgacggt tagagaaaat
      541 ttatctctag cacttaataa agggaaatta ttgaacttaa aaaaatgtct tcgtcataaa
      601 acgaatgact tggaacactt acttgaagga atttctttgg atttaaaaaa atatttagat
      661 attaaagtac aatatctttc aggaggtcaa agacaatcac tatcactaat tatgtctagc
      721 ttagcaagtc ctaaggtctt attactagac gaacatacag cagcacttga cccaaaaaca
      781 tcaaatgaag taatagagtt aacagataaa atcgtaagag aaaaaaatat aactacactt
      841 atggttactc acaacttgaa acacgctctt caatatggag ataggttgat aatgcttcat
      901 aagggtgaag ttgtattaga tgtaaaagat aaagaaaaag aagatttaac agttgaagaa
      961 atcttagaaa aatttgaata tgcagtataa gaaattaaaa tcttagtttt aatcagaaat
     1021 atttataatc tatcatatga atatatgaac aaatataatt aataaatttt aagggaggaa
     1081 aataaaatga taaaaagtaa aaaaatatta agtttaatta tagcaggagt acttggtgta
     1141 tcaatgctta ctggatgttc tcaaaatgat ggctccaatg cttcaaatga aaataaagaa
     1201 acagatagca aaaaacaaaa aaatataggt attactcaat tagtggaaca tccatctctg
     1261 gataaagcaa agaaaggatt catcaaagca ctcgaagata aaggctataa agatggagat
     1321 aatataaaaa tagatttcca aaatgcacaa aatgatatgc ctactacaca aagtattgct
     1381 agtaagtttg tatccgacaa aaaagatttg atatatgcta tatctactcc atctgcacaa
     1441 gcagcttata atgctactaa agatattccg ataataatga ctgctgttac agaccctgta
     1501 gaagctggac ttgttaaatc tcttgaaaaa ccaggtggaa atgtttctgg tacatctgat
     1561 tatctttcaa ttgataaaac attagaattg gttaaaacat tgactccaaa agcaaagaaa
     1621 ataggggtta tatacaatac tagtgaagtt aattcaaaaa tccaagttga ttctctacat
     1681 gattatgcta agaaaaataa ttatgaagta gttgaaaaag gaatcagctc ttcaagtgaa
     1741 gttaaccaag ctatttctag tttagttggc aaaatagatg ttttatatgt ccctactgac
     1801 aatttaatag tttcttctat gccaatagtt tctaaagttg ctaatgaaaa caagattcct
     1861 ataatagcct ctgaagaagg ttctgtatct tctggtgctt tagcttgttg tggaatagat
     1921 tatgaaaaac taggttataa ggctggagaa cttgctattg aagtattaga aggaaaatct
     1981 gttggcgata taccagttac tacattagat gaaactgaaa taataattaa cgaagataca
     2041 ctaaaagcac ttgacatgca aaagttatca gcagataata taaagtatat aaagtcagat
     2101 gaaaatgcaa aatctgcaaa ataaaactta ttaatttcaa aaaataggta atatgaagta
     2161 ggtaatatga aaactttata taataagtac tcttatccac cctaaccctt tgaaaattgt
     2221 gcttattgta gcaatttgaa tattgcatat aaagttattc attttccata aaagtcgtct
     2281 atattgacga ctgattatga aagttatata actttctaat cactacttga gctgtccaaa
     2341 agaattttaa tattctccag acagcttttt tttatgatat ttgattgata tacatgtcta
     2401 gttattccat atttagtaaa tattttgata aaatttccac attcacttat aacttaggat
     2461 aacgtttttt gcaaacaata cattaattta aaagtattct gagtatacat tatttagtat
     2521 tttaattaaa tttagcagtt gacttttatt attgtataat ttataattta taacaagtcg
     2581 agaatacata taattttctg actaattaaa atattaaaag ggagagataa ttatgaatac
     2641 tttattaaac aatagaaaat attattatta ttatagccac tatttttagg gtttgtacct
     2701 acgttttaac atagatacag accccttaag actactaaaa ttttgggatt gtatctatgt
     2761 tggctatatt gtttataaag ttttcattta actatataag agccacatag attaaactat
     2821 gtggcttatt cgtgttttta ccacatagtt ttgtacacta tgtggttttt ttatacacaa
     2881 aattagcaaa taattaaaat tataaaaata ttttcaaagg agtgttttat ttatgtcagg
     2941 tattatatct gtaatgacgc aaagtttaat tttatcgatt atggcactgg gggtttatat
     3001 aacttacaaa atcttagatt ttccagatat gtctgctgat ggtagctata caatgggtgc
     3061 ttctattgta gcattttctc ttactaatgg tatttctcct gtagtagcaa ctttaatggc
     3121 tatcttatgt ggttgtactg ctggtcttgt tacagggatt cttcacatta agtttaagat
     3181 atctaactta ctttctggta ttttagttat gggaatgcta tactctatca atttaagaat
     3241 aatgggaaaa tcaaatattc ctctatttag ctttaaacac ttattcaatg gggaaatatc
     3301 tcctatagtt ttagccttag cttttgtatt catctgtaaa gtccttttag atttattcct
     3361 aaaaacaggt cttggataca ctttaaaagg tgttggtgat aattctcaaa tgattaaatc
     3421 cctaggtata aatataggtt ctataaaaat actaggactt atgatttcaa atggacttat
     3481 agctttatct ggtagtctta tggctcagtt cttgggattc tcagatgtaa atatgggtat
     3541 aggaacttta gttcttggaa ttgcc
//
LOCUS       DAEPXW010000194         3540 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.198, whole genome shotgun sequence.
ACCESSION   DAEPXW010000194 DAEPXW010000000
VERSION     DAEPXW010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3540
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.198"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     repeat_region   152..1622
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=284..312
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            2269..3540
                     /locus_tag="KRM55_003636"
     CDS             2269..3540
                     /locus_tag="KRM55_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1595821.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIMLEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
BASE COUNT         1390 a          501 c          412 g         1237 t
ORIGIN      
        1 tttataatta ttctactttt atattttaat cattaaaact aaagtcaata ttatctggta
       61 attatttact acaaatgcta aaaaataatt atattttaaa ggagaaaatg ctgtataaat
      121 tattggggta ttttacctat acttgttgca aatttacata ccacatagtt aatataaaac
      181 tattaatagt gctatgttgt ttatttgcat taacaagatt tacatacctc atagttaata
      241 taaaacaatc tcttatactg aatacattag tttttaaagt gttatttaca taccacttag
      301 ttaatataaa acactcgaat ttcctgtttc aatattactg acatgttgat ttacatacca
      361 cttagttaat ataaaacgat aatatacgtg attatgatgt tgcttttgac tatatttaca
      421 taccacttag ttaatataaa actctgggtc aacaggagga ttagggtctg gactatttac
      481 ataccactta gttaatataa aactgtaatc atagttccaa ttagccactt taacatgcat
      541 ttacatacca cttagttaat ataaaaccct taaataatat cctccaactc aacctcaact
      601 ctatttacat accacttagt taatataaaa ccagcatctt ctcttatcac tattgtttca
      661 gcaattttat ttacatacca cttagttaat ataaaacatg cttaacttca tactcaaata
      721 acgagcgaat ttgaatttac ataccactta gttaatataa aactttattt aaaaattatg
      781 ttttacatgg gtttacttta tttacatacc acttagttaa tataaaacat ttactagtat
      841 ttttccataa tttgttctat ttttatttac ataccactta gttaatataa aacgatataa
      901 gtaacttaga agtaatacat agtaagtcaa atttacatac cacttagtta atataaaact
      961 aaaatcaaaa aatgagtctt ataacaccac taattaattt acataccact tagttaatat
     1021 aaaaccaatc actccattct agttttaatc ttatctatta atgtatttac ataccactta
     1081 gttaatataa aactagatgt accatacctt ccacttatag ttccagttat atttacatac
     1141 cacttagtta atataaaacc aagtaaatat gttacaggat gtctaatacc ttcttattta
     1201 cataccactt agttaatata aaacaaagta aagcggtagt aaatgctata gattatactc
     1261 caatttacat accacttagt taatataaaa ctggaacaga ctttataaga atatacaaca
     1321 atagtgccga tttacatacc acttagttaa tataaaaccc atacgaaaaa attgaaactg
     1381 agagtaaaat gaacaattta cataccactt agttaatata aaacacacca gaacctttca
     1441 aagtgcttaa taaagataaa aatttacata ccacttagtt aatataaaac ctataattag
     1501 tattaaaaaa attcttaatt ctatacaatt tacataccac ttagttaata taaaacaaaa
     1561 tgttgtaaaa gtaactgaaa ctgtaaacga cttatttaca taccacttag ttaatataaa
     1621 accccaaaat aaactaagta ttttcagtac ttacacacat acaactctct caaatttgca
     1681 gtgaaccatg agtagtgcaa ttgataacat ttatcataca ccctcaatcc cttacattgc
     1741 aactgttaaa ccctacttta tcaaaaatat cgctcactgc aaaatttata tatttttatt
     1801 atatcataaa attcaaacta taaaattaaa atggaataat ttatcaattt aagaacacct
     1861 acatatttgt aaatacttac tatattatct attctaatag ttcttcttct agctagaact
     1921 aatataaaaa tcatctctga aagattagga catactaata taaaaataac tatgaataga
     1981 tattttcttg ttttaaacga tatggataaa aaaacttctg aaaatataat caaagttctc
     2041 tttaaataac attccatttt atgtaagtag gcattatatt tttcttaaat gtcacttaaa
     2101 tgtcagttat atataataat agtaaacaac tgtatttcac taatatttgc tattatctaa
     2161 tagtatttat agtttagatt tgatataata catgtggtaa aattttgatt tgtaaaacaa
     2221 aattttacct acatatatta aaacaaattt aaaactaagg agacctatat gttaaaagta
     2281 ctaaaaggaa atataatttt tacaaaaact tcagaaactt tcacagtatt tgaaaatagt
     2341 tatattatgc tggaaaaagg taaagtaaag ggaatattta aagagatacc taaggaatac
     2401 aaaaacctaa aagtagtaga ttacactgat aagcttataa tacctggtat gaatgacctc
     2461 catgcccatg cctctcaatt taaaaatctt ggaatggcta tggataaaga gcttttgcca
     2521 tggcttgaaa cttatacatt tccagaagaa tcaaattata aagatataga atatgcaaca
     2581 aaaatgtata aaaaatttgt aaaagaactt tggaaatctg gaactacaag aatagcagtg
     2641 tttgcaacag tacataaaga agcctctatg aaacttatgg atatattcaa agaagttggt
     2701 cttggagcat acgttggtaa agtaaatatg aatatgaatt gccctgatac tttattagaa
     2761 aacactcagg attctattac tgatacagaa gaaattataa ataagtatag tgatacagat
     2821 tctattgtaa aaccaataat aacacctaga tttataccaa gctgtacaag tgaactttta
     2881 aaaggtttag gagatttatg tttaaaatat aatattccta ttcaatcaca cttatctgaa
     2941 aattatgatg agattgaatg ggttagaagt ctagaacctg aatctaaatt ctatggagat
     3001 gcatataata gatataattt atttggtcaa actcctactt taatggctca ttgtgttcat
     3061 tgttctcagg atgaaataga tttaatgaga gaaaataatg ttatggcagt tcactgtcca
     3121 gcttctaact ttaatgttgg tagtggtgct atgcctatca gaaaattaat cgataataat
     3181 attagattag cacttggatc agatataagt ggtggacata cattgtcaat atttaaagca
     3241 atggtatctg caatacaatt atctaaatta tattgggtta actctggtaa gaagtataat
     3301 ttcttatctt tatctgaggc tttttatatt gcaaccaaaa gtggtggaag tttctttgga
     3361 aaagttggta gctttgaaga aggttatgat tttgatgcat tgattattga tgattcaaat
     3421 ttaaatcatg acaattattc tatacttgaa agacttgaaa gatttatata tgttggtgat
     3481 gatagaaata tcattcatag atatgtatgt ggaaaactaa ttgaagaacc taatatataa
//
LOCUS       DAEPXW010000195         3533 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.199, whole genome shotgun sequence.
ACCESSION   DAEPXW010000195 DAEPXW010000000
VERSION     DAEPXW010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.199"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(1036..1587)
                     /locus_tag="KRM55_003637"
     CDS             complement(1036..1587)
                     /locus_tag="KRM55_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595822.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            1778..2740
                     /locus_tag="KRM55_003638"
     CDS             1778..2740
                     /locus_tag="KRM55_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBH1595823.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            3035..>3533
                     /locus_tag="KRM55_003639"
     CDS             3035..>3533
                     /locus_tag="KRM55_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HBH1595824.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPE"
BASE COUNT         1391 a          350 c          520 g         1272 t
ORIGIN      
        1 tattagatat aaaaaataat taccttataa atagattgaa atttatgaat attcatacta
       61 taatttaaat ataaggagat gccctttgaa aataaaaatt aaaaaatatt taatgctatt
      121 acaataggaa ctagaactac acttaataaa tatacagaaa ttagatttgg ctcaatataa
      181 aatacaaata tagaatttag gtgtttttta tgaaaaaatt tttatatgct ttatatagtt
      241 tcattgttat tatagctaat tttagattaa aagaaaaaaa ttataacttt attttattag
      301 caatcttttt tatattgctg ttaattcaaa atggagtttt aaaaacaggt tatcaaaata
      361 gagctacatt ttatcaagat aattatttta atagagagga taaaaatgat aagataaaat
      421 ttatgactat aaagattttt atatttttgt cattaccatt atgttttaat atactattca
      481 attatttaac ctcttaaatt atatttagat ataggagtct tatgataaaa gtaagcttat
      541 gtgttatttg tagtaaatat aaagtgcata tagtgataaa acaaaagttt tatataaatg
      601 aagaaaaaaa tataaaataa tttatttaac tacttaaaaa taaactaaaa gggataataa
      661 aatagctttt aggttatggt aataaaggta tttaaaaaga gtgcataagc actccaattg
      721 tgagaaatac atacacaaat cattattaca acaatgaaaa atgtacatat aagagacgtt
      781 ttgtatttgt tttaagtgat aatattttaa tactaactaa ataattatca caatagtaaa
      841 aaagaaaaag gagtattttg tactccattt gtcaaaaata taaaactttt atataagctt
      901 attataacat aattgataaa agtgtaaaga tatataatga atttataaag aaaaataaaa
      961 taaaaaagat aaatcctaat caaaggattt atctttttgt atagaaaata attattctat
     1021 tattaaatgg catgactaaa ctggataata atttattatt actgctttca atgttttttc
     1081 tccttgatta tggtatgtat gaattgattc agctgaaaaa caaatagagt cattttctct
     1141 aagttgataa atagagtcat ttacttctaa ttttaattga ccttctataa tcataatata
     1201 ttcctgtgat ttttcagaat gaccaacaga tgtataacta tgaccttctt ctaattccat
     1261 ttgaaataat tcgaagtttc tagttggtgt attgggataa taacaataaa gacgataatc
     1321 tttattttct gaaacttgta catctatatc agtttttgat acaataaaag tttcattttg
     1381 aggttgttcc agtattgcag tatatggaac atttagtcca cttgcaattt tccaaattgt
     1441 gtttactgtt gggtttgagt ctcccttttc aatttgcgaa agcattactt tacttacgcc
     1501 agataattca gcaagttgac ctagacttaa gttacgttca ttacgtaatc tatttaaatt
     1561 tttagcaata acagtattaa tactcatagt aactccttaa aatgtaaatt attgacaaat
     1621 ataatttacg aatgtataat ttatttaaca ttatttataa tttacaaatg tataatataa
     1681 tgaacgttaa atatactgta catccgtaat ataaattata ctgcataaag agttgttttt
     1741 caacggatga tagttgagag attaaggggg aattgtaatg cgtgtactta ataatgttac
     1801 agaggctata ggcaatactc atatgttaca tttatccaaa atagcagatg aatttggagt
     1861 tcaaggtaat atttatgcaa agatggaata cttaaatccg ggatttagta aaaaggaccg
     1921 tgtagcatta caaatgatta ccgaagcaga aaatgcaggt ttattagttc caggtcaagc
     1981 agttgtggaa ttaacaagtg gtaatactgg aacaggacta gcaatagctt gtgcatgtaa
     2041 aggatataaa tttatagcgt gtatgtcaaa aggaaattct atggaaagag caagaatgat
     2101 gaaagcttta ggtgctgaag tagttcttgt agaccaaatg cctaattcag ttcatggaca
     2161 ggtatctggt gaagatttgg cacttgtaga aattgaggct caaaaaatag caaaagaaag
     2221 aaatgcattt agagcagacc aatttaattt agaagcttgt aatcatgcac atgaaaagta
     2281 tacagcagaa gaaatgtggg aacaattgga tggaaatatt gatgtatttg tagattttct
     2341 tggaagtggt agtacttttg caggatgttc aaaaacactt aaaaaacata attcttctat
     2401 caaatgttat gttgttgaac ctgaaacagc agcaatttat tcaggtaaag aaataactga
     2461 ccaagggcat aaaatacaag gtggaggata ttctatggat ttgccattag tagacaagaa
     2521 acttattgat ggttatattc aagttacaga cgaggaggca actgatgtag caagaaaatt
     2581 agctaaatta gaaggtgtat ttgcaggatt ttcttcaggg gcaaatgtat gtgcagcaat
     2641 taagttatta aagagcagtg aaaaaggaaa aaatatagtt ttaactctta atgatagtgg
     2701 tttaaaatat ttaagtactg atttatatga agaattgtaa taatagcaca atagttatgc
     2761 aatgtttttt aaattaagta tatagattta aattataaaa agtatctcaa tgtaattttt
     2821 gaaagttata aaggagatac ttttttattt tgtaaatatg gagtatccta cttataagta
     2881 ttaagctata tagatattga tgattagcta tgcaataaaa aagagtatgt gtttttgcat
     2941 ttatacatca taacttggaa taatacatat taatgttcta aatgtattta aaacatatga
     3001 taaaattaga acaaatagat acaaggagat aaaaatgcaa aagagaattt taagaaattt
     3061 tatatttacg ggtaaaaata ttttaagtaa acttgttttt ataataaaat ataattttag
     3121 tacattaatt ttatttgaat tatttcataa aggattagcc ttatttttta tatggccatc
     3181 tattagatat atatttgata ttttaataaa aagtttacat atagtctacc taaatatgga
     3241 taattttata aaagttttga ccaatcccat gtcaatagtt ctgataatac tatcagttat
     3301 aatactagct ttttatgcat tttttgaatt tacctctgta attatttgtt ttaataaatc
     3361 gataaaatat gaaaaaatag ggttatttga actctttaaa atatcatttg agaactctat
     3421 aaaattgtta tatcctaaaa atatactatt atttatattt gtgatattaa taattccatt
     3481 agtaaataca gttttaattt cagggtttat aggaaaaata caaataccag agt
//
LOCUS       DAEPXW010000196         3528 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.200, whole genome shotgun sequence.
ACCESSION   DAEPXW010000196 DAEPXW010000000
VERSION     DAEPXW010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3528
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.200"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(21..1151)
                     /locus_tag="KRM55_003640"
     CDS             complement(21..1151)
                     /locus_tag="KRM55_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH1595825.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            complement(1538..3475)
                     /gene="htpG"
                     /locus_tag="KRM55_003641"
     CDS             complement(1538..3475)
                     /gene="htpG"
                     /locus_tag="KRM55_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBH1595826.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
BASE COUNT         1107 a          625 c          348 g         1448 t
ORIGIN      
        1 actaaatatg taaagtcaaa ttataaagac ttatggtaca tttcctttat ttgttcctta
       61 ttaaaatact ttggatgtct cttaatattt gcaactgata ttttcataca attatcagtt
      121 aaccaatcta tatctgattt ttcaatacct aaatcactta gttttatatc taaatctatt
      181 tttttaagga aatttctaat tgcatctgaa caatcttctg cacaagttcc tcctaatacc
      241 tttgaaatat taccaaatct ttcaatatca ctatcccatg aactttctat aatagtagga
      301 gtcaaagctg caagtccttt tccatgcatt acatctctaa gaccacttac aggatgctcc
      361 attccatgtg gcaaggctgt acccgctgta ccaatcgtca ttcctccaat agtacttgca
      421 agtgttattt tttcccatgc ttctaaatca ttaacatcat tatatacctt tattaggttt
      481 tctgatataa gttcaatccc ataaatagct tgtacatctg caagagggtt tcttccatta
      541 gaaagatatg cttccatatt atgggcaagt gcatcaaatc caactgatgc aattatatgt
      601 tttggcattg taaccataag ttctgggtca attattgatg cttttgcata catactattc
      661 ttctttatag attttttatc tttagtttct gaatttgtaa gtactgcaaa acaatttcct
      721 tcactacctg tacctgatgt tgttggaact aagattatag gtaaagcttc ttcaccttgt
      781 ctaattccaa atatataatc atttaaatct cctgggtttt tataagaaaa agctatactc
      841 ttggcagcat ccataatgct tccaccacca agacctaaaa cacaatcaca tccagttgat
      901 tttataattt ctactcctga atatatagta gttataagag gattttgttc tactctatca
      961 aaaacttcat attctatttt agagtctttt agtaaatcta ttgttttatc aagtaatcca
     1021 gttttctttg tactattttt acctgttact atcaatactt ttttgccata tttagatact
     1081 tcttttccca catcattaat tctgcctctc ccaaataaga tatttactgg caaattataa
     1141 ttaaaattca ttctaaaacc tcctatttct actttagtaa taattttatg tttttaacaa
     1201 agtgtaatta tgtatttaaa cataaactaa aaaacaatct tttacttaat tatatgtatt
     1261 atcttattat atatcaagtt aactatattt aactaaatag agttttttat tagaacctac
     1321 ttaaatattt aaaattaacc aaagataaaa aaataaagaa tggtctgtct caaaatagag
     1381 ataaatatat ttttcattgt tgaaatgatt aaaataaatt taatttcaca taaaaaaagc
     1441 gcctcatgaa ctgaaaagtt cattttgaga cacttctttc ttatcactga tattgaatac
     1501 tttttataaa tttgcttcaa tgtattcaaa ttcaatctta taattctatc aaaagactca
     1561 taagcttatt acttctttgt acaaatgaat ctaactcatc tggctttaat tctttattag
     1621 aaagtaaagc taaatctgct atctggttac aaataagtgt aatcttatct ttcttttcct
     1681 catcatcttt aagagaaacc aattttttga ttattggact gttctcattt attacaagag
     1741 ttttttcttc ctcaaaattc attcctaaat ccattccagc aaatcttgac tgcatttctg
     1801 ccattctaat agattgttct gatactaata ccatagctgg agtgtcttca tttttcaatc
     1861 cttctacaga ataattcttc actctttctc cgacagcttc tttaaacaaa ccttctatct
     1921 tagctatctc ttctttgttt tcttcactat ctttattttc atttttatct tttaatacat
     1981 cagaaaggtc tgcatctatt ctattaaact taactccatt ctctttatat tccataaatg
     2041 aaataaaatg agtatctatt gatgagttta aaacaacagc acttaagtcg tattctttaa
     2101 atagtttaat gtattgagat tgctgttcct tatcacttac ataaaatacc ttattttcat
     2161 gtttgtcctt acatttttct aaataatctt gtaatgttat atactcatca tcaatagttt
     2221 tgaataatat acattctttt accttctcat agaaactttc atcttttaag caaccatatt
     2281 taataaatat ttgtatatca tcccaaaact tattgtattc ttctctttca tttttacaaa
     2341 gagattttaa cttatcagct acttttttaa ttatatgctt agaaattttg cttacgtctc
     2401 tgtcattttg taagaaactt cttgatacat ttaatggtaa gtctgggcag tctataacac
     2461 cttttaataa aagtaaaaat tctggtataa cttcttttat attgtcagcc acaaacactt
     2521 gattgttgta taattttact tttccttcag tcagttcaaa ctcatttttt aatttaggga
     2581 agtaaagtat accctttaaa ttgaaaggat aatctacatt taaatgtatc caaaataaag
     2641 gttcatcaaa tacattgaat acctttctat aaaactcttt atactcctca tcagtacagt
     2701 cttttggaga ttttaaccat agaggattag tgtcgtttaa aggctcaatt acttttgcat
     2761 ctacaatctc ttcttttcca tcttcctttt gttttttagc tttttcttct gcttctttag
     2821 cttctctttc taatctttca acatcttcta aatatatttc tactggtaag aaagaacagt
     2881 atttatttat tattcctctt acagtaaatt catctaaaaa ttctttacta tcatcatcaa
     2941 taaatagtgt tatagtagtt cctctatcat ttctagcatc tgattcagat atttcgtatt
     3001 ctgtaccacc ttcagatatc catcttacag gagtcgctcc ttctgtatat gaaagtgtat
     3061 ctatttgtac ctttttagac accataaatg cagaataaaa tcctaatcca aaatgaccta
     3121 ttatatcatt tgactcttcc attttatcct tatatttatt aaagaaatct tcagcacctg
     3181 aaaaagcaac ttgatttatg tattttttta tctcttcttc agtcatacca attccattgt
     3241 caataaattt aagtgtacct tctcctttat ttacagatac tgtaatttta taatctgatg
     3301 acttattttc tgatatttct cctagtgata caagtctttt atgtttactt actgcatcac
     3361 atccattact tataagctct cttataaata tgtctttatc agagtataac cattttttaa
     3421 ttataggaaa aatattttct gtatgaattg aaatactccc tttttcaaat tccatttttt
     3481 atccctcctc attttataat taatatttta aattttttaa aatggtat
//
LOCUS       DAEPXW010000197         3456 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.201, whole genome shotgun sequence.
ACCESSION   DAEPXW010000197 DAEPXW010000000
VERSION     DAEPXW010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3456
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.201"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(56..628)
                     /locus_tag="KRM55_003642"
     CDS             complement(56..628)
                     /locus_tag="KRM55_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1595827.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(657..923)
                     /locus_tag="KRM55_003643"
     CDS             complement(657..923)
                     /locus_tag="KRM55_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH1595828.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            complement(923..1132)
                     /locus_tag="KRM55_003644"
     CDS             complement(923..1132)
                     /locus_tag="KRM55_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH1595829.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            1401..2261
                     /locus_tag="KRM55_003645"
     CDS             1401..2261
                     /locus_tag="KRM55_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH1595830.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2309..3337
                     /locus_tag="KRM55_003646"
     CDS             2309..3337
                     /locus_tag="KRM55_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH1595831.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNKI"
BASE COUNT         1356 a          385 c          556 g         1159 t
ORIGIN      
        1 aacacaacag taaattataa attatcaaat aataatagtt atacaaataa aaattttaga
       61 acattttttg agattcttct aactcgtaag catccattaa ggcttcacca aatctttgat
      121 aatgaattat ttctctttga cccaagaatt ttaatacatc tataacatca acgtcatctg
      181 ttaggtttat aagttgataa taagttgcaa gtgctttttg ttcagctgcc atatcctcat
      241 gtaaatcggt tacgggattt gacataactg ctataggtct tacatcaaat ggaacaccat
      301 ttgaatctgt tggataaatt ccatatccat tttgagcata gtttgaacca agacctgcag
      361 cttttaactc ttctgggctt gcatcagaag ttaactgata aaccatagta catataagct
      421 caacgtgagc tagttcttct gtaccaatat ctgttaaaag tgcacgcata ttaccagtag
      481 gcattgtata tctttggctt aaatatctta aagatgcagc aagttctcca tttggcccac
      541 caaattgagt tataagaaat ttagccattc tagggtcaca agtttttata ttaactgggt
      601 gttgtatagt tttctgatat atccacatga attttcaatc ctccaatact tgatgtctaa
      661 taattaaatt ctctgtccca aggccaaggt tggtcagccc attgccaagg gcatctactt
      721 ggagcatacc caaagttagt taaaggaccg tatttatttt cgtaagcata tctagcttgc
      781 gcaaattgat tacataatga attataagtg ttgatagcat ttttatcatc agggtgattg
      841 tctaaatata agttcatatc aacacatgca aaagatgttt cctgaacttt tctcataagt
      901 tcagctctag atgagtcttt cattatcttc tacctcctct atattttttt ggcttagcat
      961 ataattcttt gttgtacatt tcagactcta gtaagtttag ttctggaaat atagttccaa
     1021 attttaatgc atcagaaagg cagtacattt ctgtgaaaat ttgattatta atgtatggtc
     1081 tagccaaaga tggaccacaa ttttttttga tatctctagt cttattttcc aagatgaaaa
     1141 cctccttgtt gtaaatagat aggtaactct atctagtgta taatattcaa tcatttaaaa
     1201 atcgttacta ataataaaat attaaatgag aaaaataaaa aagataataa aagaaagagg
     1261 ttatttatgt tattataagt ttatgtgtta ttgtaaacta taaattattt agtaaaatta
     1321 aagtaaaaat tatagtattt tgtggatgaa ggtagacttt tttgtaaaat attattaaca
     1381 taaatatacg aggtgattag atgagtgaac tatcaggaaa aggctgtgaa attatagttc
     1441 cttttgagga aagacttcca gtaagagata tagaaaaaag tataataaaa aaatatagga
     1501 aaaatttatg gtctaagttt atgaaggcaa taagagatta taaattggtt gaagaaggtg
     1561 ataagatagc tgtagcgatt tctggtggaa aagacagtat tcttatggct aaaatgtttc
     1621 aagagttaaa aaaacatgga caagttaatt ttgatgttga atttattgct atggaccctg
     1681 gatatcatgc aaatataaga caattactta tagataattg tgagtatcta aatataccaa
     1741 tacatttatt tgattcaagg atatttgaga tagcagatga aatagcaaaa gattatccat
     1801 gctatatgtg tgcaagaatg aggagaggag cattatattc aaaggcagaa gaattagggt
     1861 gcaacaaact tgcattaggt catcattatg atgatgtaat agagacaaca atgcttaact
     1921 tattgtgtgc tggaaatttt aaaacaatgc ttcctaaact taattctact aattttgaag
     1981 gtataaaaat tataagacca ctttattata taagagaaga acatattata agatttattc
     2041 aaaatagtgg tatatggcca ttaaattgtg catgtatggt tgctgctaaa aaaacaggta
     2101 ataaaagata tgagataaaa gacttaataa agagtttaga atcaaatttt aaaaatgtag
     2161 aaaaatctat atttaaggcg gcagaaaatg taaatcttga ttcagtactt ggttggcaaa
     2221 aagatgggga gaaacattct ttcttagaaa attttgaata aaaatagtta aaaagaatca
     2281 ctataaacaa ttggaaaggg tgtttatatt gaaaagagta tatatagatt ttgaaatgaa
     2341 tatgccaaat tctaaatcaa aaagagcagt atttaattct gatataattg caatcggagc
     2401 agttatgtat gatgaaaaaa caaaaaatat tgataaattt aaatctttaa taagaccagt
     2461 aagtaatgag gagttgtatc ctcatataca agaattaaca catatatctt ctgaagaatt
     2521 gaagagtgca ccaagttatg aagaggtcat gagaaagttt aaaaaatggc ttggcatatt
     2581 ttctgatatt aaaggaatat atacttttgg taatttggat ttgacatgtt tcaataacac
     2641 agatatgaga agtgctaaaa aaaataacca tccaaggttt gtaaataaca ttagagattt
     2701 atttgtagat ataaaagaaa aatatataaa ttgtggtatg agatgtatga actatatatc
     2761 attgaaaaat ttacttgaat ttgttaactt agagtttagt ggagatgccc atgacccatt
     2821 aaatgatgca tataatttat ttattttgga tgaggcaatc acaaataatg tagatataca
     2881 aaatctttta ataatacgtg acataataag accaccattt aacgatataa attctaattt
     2941 agataattgt tttaacaaat ttaaggagtc attatataaa aaagaaggaa attataatat
     3001 tgtagatttt tctgttgaaa taataaaaac tgtgagaatg tacttattaa caatcataga
     3061 tgtaaatata caaaatttag aaattatgaa agatataagt aaaaaaatgg atactataga
     3121 taaattgaaa gatatagagg aaggctattt ttatttatta gaagatgtgt acttcgatat
     3181 gaaagatgta ctagaagatt taatgcttta tagaatgaat gaagatgagt acaagtatga
     3241 gataaaaaat ataataaaaa tgtttgatga agacttagat aatgaaaaaa tatatataaa
     3301 taaatgtaat aacttaaatg ttgttaataa gatataagaa attataaata atagagtaga
     3361 acttgacaat tataacaatt ttttataaaa ctgaatcaag ataaaattaa attaatatta
     3421 aaataatata caataaaaaa atgtagagag atactt
//
LOCUS       DAEPXW010000198         3445 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.202, whole genome shotgun sequence.
ACCESSION   DAEPXW010000198 DAEPXW010000000
VERSION     DAEPXW010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.202"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            166..504
                     /locus_tag="KRM55_003647"
     CDS             166..504
                     /locus_tag="KRM55_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBH1595832.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            970..1473
                     /locus_tag="KRM55_003648"
     CDS             970..1473
                     /locus_tag="KRM55_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBH1595833.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            1520..2479
                     /gene="moaA"
                     /locus_tag="KRM55_003649"
     CDS             1520..2479
                     /gene="moaA"
                     /locus_tag="KRM55_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBH1595834.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            2483..2953
                     /gene="moaC"
                     /locus_tag="KRM55_003650"
     CDS             2483..2953
                     /gene="moaC"
                     /locus_tag="KRM55_003650"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBH1595835.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            2989..3420
                     /locus_tag="KRM55_003651"
     CDS             2989..3420
                     /locus_tag="KRM55_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBH1595836.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         1441 a          303 c          660 g         1041 t
ORIGIN      
        1 aataataaaa atataattag ttaataaaac atattatttt atagtataga ttggttaata
       61 aaagtacaga ttggttaatg aaacattaaa ttacaatatt tgttaaaaaa attgtgagtt
      121 acatgatata atgtattaaa taggatacta aggagttgat atattatgtt aatagtaact
      181 acagaaaaag tagaaggtaa aaagatatca aaggttttag gattagtgag aggaagtaca
      241 ataagagcaa aacatgttgg aaaagatata ggagcaagtt ttaaaaatct tgttggagga
      301 gaacttactg gatataatga aatgctcact gaagcaagac aaattgccat aggtagaatg
      361 gttgaagatg cagaagctaa aggtgcaaac gcagtaatag catttagact gtcttcagct
      421 tcagttatgc aaggggcagc agaaatgctt gcttatggaa cagcagttgt tttagaagat
      481 gataatagta ttcttgaaaa ataaaatata aatagttaaa aagaggcatc ttttaaaaat
      541 tttatggatg ccttttttta tttgaaaaaa ctaatttgag aagaaatttt aactattatg
      601 acaataaaat tagggtgata ttatataaat aagtaaaatt atattatata atgtatggta
      661 tagactttaa aaattttatt tgtagagaaa aatatggaca atgttataat aattatagaa
      721 attaaaagta cttacattca ttatgtatgt gacatgtata attagtttta tatttaatac
      781 agttttgaag taatatcttc attttgagaa cgttggaata ataaaaaatg tattattata
      841 ggtgatataa ataaaaaata aatataatat gttatattgc tgatagaaaa gagaataaaa
      901 gaaaataggt tttattaaaa gagattttta tttataggac ttaatcaatg tatagagggg
      961 tgagaacgta tgtttaatgt tgcaattata acacttagtg ataaaggata tgaaggaaaa
     1021 agagaagata taacaggaaa aaagttaact gaatttgttg aaaatacagg agcttataaa
     1081 gttactgaat atgtacttat aaaagatgat aaggaaatgc taaaggaaaa tattataaga
     1141 ctttgtaata gtaataaaat agatttaatt cttacaaatg gaggtactgg tttttcaaaa
     1201 agagatataa ccccagaagc aactaaggaa gtgttggaaa aagaaatacc aggtctgagc
     1261 gaatatatga gaatgaaatc cacagaaatt actaaaaagg ccatactaag taggggtgta
     1321 agtggaataa gaaataattc tataataata aatttacctg gaagtcctaa aggtgcagtt
     1381 gaaaatctaa gttttataat tgatgtttta gaccatggca tagaagtttt aagaggagaa
     1441 gctacagaat gtgccactaa aaaaagtgaa tagtatataa tctagataga taaaaaatag
     1501 acaaagaggt agataaagta tgattgataa gtatggaaga aaaatagact accttcgtat
     1561 ttcacttaca gataagtgta atttaaggtg tgtctattgt atgccaccag atgtaaaatt
     1621 tgataaaaat tatataaatg aaaatctaag ctttgaagac tacaagttta ttataaaggc
     1681 tatggctgaa caaggtataa caaaaattag atttactgga ggagaacctc ttttatatcc
     1741 taaattaaat gagcttataa aatttacaaa agaagaatgt ggaataaata acataggaat
     1801 gaccactaat gctattgggc tttctgatag aatctttgag cttgaaaaat gtggcttaaa
     1861 taaagttaat ataagtttag attctttgaa ggaatataag tataaatccg taacaagagg
     1921 aggaaactta aaagatgtct taaaatcgat tgaatcttgt ttaaacttag gtataaaagt
     1981 aaagttaaat tgcgttgcta taagtgggtt taatgatgat gagcttaaag attttatgtt
     2041 tttaacagtt aaatcaccaa ttgatgtaag atttatagag cttatgccat taggtgaggc
     2101 taatagagtt tataagaagg gttattttaa tgtaaaagaa atgattgaaa aaatatatgg
     2161 tttatataaa gtcaaaaatg atgaaaaaag tacagcagaa tattatatgt ttaaaggagc
     2221 taaaggaaga ataggaatta taactccatt aagctgttca ttttgtaaca cttgtaatcg
     2281 tattagactt acttctagtg gtgcaataaa attatgtcta cattcaaaag aagaaataga
     2341 tataaaacca tttttacata aaccattgtt atttagagaa tctatgaaag atataataaa
     2401 acaaaaacca gaaaaacatc atttaataga aaataaatgt agtgatacaa ataggcgtat
     2461 gtatgaaatt ggaggataag taatgttaac acatataaat gaaaaagggt atgccaagat
     2521 ggtggacata agtgaaaaag atgatactaa aagaacggcc gtagctacag ctacaattac
     2581 tcttagtaag gaagcattag aaaaagtaaa aaatggtcag ataaaaaaag gagacgtatt
     2641 gtctgtagct caagttgcag gtataatggg agctaaaaat acatcttcaa acataccaat
     2701 gtgccatcag attaaattag ttggatgtga tttagaattt gatgtagatg attctatgtc
     2761 tgctattaag atatacgcaa cctgtaaatc tcttgggaaa actggagtag aaatggaagc
     2821 tttaaatgca tgttctttag cagcacttac aatttatgat atgtgtaaag cagttgataa
     2881 aaaaatggtt ataagtaata tccatcttgt agagaagact ggtggaaaat caggagattt
     2941 taagttcgag taaattaata atatattggg ttaaaatttg gaggaaatat ggcgaaggta
     3001 gtgtcaataa atataagtga gaaaaaaggt gtaattaaag ttcctgtaca atgtgcagag
     3061 ctaaaaataa atcatgggat agttggagat gcacatgcag gaaactggca tcgtcagata
     3121 agcttacttg gaaaagaaag catagataaa atgaaaatga aaggctttga ccaattaaaa
     3181 tatggagatt ttgctgaaaa tgtaactaca gaagggatag aagttttttc cctgcctgtt
     3241 ggtacaaagt taagaatagg gcaatgtgaa gttgaagtaa ctcaaatagg gaaaaaatgt
     3301 cacaatggat gtgaaattaa gaaattgaca ggtgactgtg tgatgccacg agaaggaatt
     3361 tttgtaaagg ttctaaaaga aggaattata aatgtgaatg attcaataga tgtaatctaa
     3421 tgaagtcact attaaaatat aatta
//
LOCUS       DAEPXW010000199         3437 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.203, whole genome shotgun sequence.
ACCESSION   DAEPXW010000199 DAEPXW010000000
VERSION     DAEPXW010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3437
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.203"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(94..1661)
                     /locus_tag="KRM55_003652"
                     /pseudo
     CDS             complement(94..1661)
                     /locus_tag="KRM55_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(1636..1779)
                     /locus_tag="KRM55_003653"
     CDS             complement(1636..1779)
                     /locus_tag="KRM55_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595837.1"
                     /translation="MYVYHFESPEKFAFNKVIRTKNQNEISLEKFNEFKETIQDKLLP
                     YNR"
     gene            complement(1987..2169)
                     /locus_tag="KRM55_003654"
     CDS             complement(1987..2169)
                     /locus_tag="KRM55_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595838.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
     gene            complement(2558..3304)
                     /gene="cdtR"
                     /locus_tag="KRM55_003655"
     CDS             complement(2558..3304)
                     /gene="cdtR"
                     /locus_tag="KRM55_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HBH1595839.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT         1141 a          450 c          376 g         1470 t
ORIGIN      
        1 tttaaataaa aaatacctta taaagttaat tttttaatac tttataaggt aaatacatat
       61 tgtattgtgg ggataaattt aaatcatttg atactaatca acactaagaa ccaataactc
      121 tctatcatct tgagtaattg tatatattct taatttcttg tatgtcataa tattttctcc
      181 acctgtaaaa taactcctaa gattaacaca atcagtttta ggttgatttg tatctcctaa
      241 ataattacgc aattctttat ctttagttcc aatatcttta aatccaaaat attgtaaagt
      301 agcttcaact ctatattttt ggacataatc gagagcttct ttattagttt atgttggtgt
      361 aaaatacata ccatttatat aagcatttat tgtacttgga ttaaatttaa aatctgcaga
      421 atatatttta tgtgtaacta ttatttcttg aacagttgga attttaactt ctggttcatc
      481 aagtatttca ggagtactat ttagctctgt aatagataag ttatctaagt atattgtatc
      541 actatcaatt aatgttatat ctatattaga agaatctttt tcagtagttt caaattcata
      601 actaaatttt gtatatcctt gttctagtac caaataatcc gttttttctt cttttacttt
      661 tatatttaca attattgaat tatatgttaa aggatttttt gaattttact aaaaacataa
      721 cgtttataag gttttagttc agacataggt attttaatct tcgtctcacc atttaatcta
      781 tttgctgagc cttttaaacc atcttgattt gtagtattaa cattactcca tatactaggg
      841 taattattgt aatcatcaaa attagtaaag taagttggtg tttttataag tatattcatt
      901 cctctttcaa gtttaacatt acatatttgt ttatcagaca aagtttttaa actgtcttta
      961 atcttattgc ctatattatc atcaaatatg agttcaacac aactttcatc tattggtata
     1021 ttattaaaat ataacaaacc atctttttta gtagtgccaa aagttttttc aattgcttct
     1081 ccaattgtaa gttcaggtgt tttatcttct gggacctgta aacttttagc agtaattctt
     1141 ctcttgtaag attcattttc tgtatctaat ataatagata cagaaatact gtcaatttga
     1201 cctatatcgt cttaccaact atttcattct gttactattt gtccagaacc attttttgta
     1261 ccaaaatttc cacttacttg tgttgtttct aatttaattt gctttccatc atctaatttt
     1321 tttaattaat tataatttat aggaatcagt ctagaactaa attgatacat tgtgttaaga
     1381 gccataggtg aaaatccttt tttgagataa gtatttccag gagatagatt attgccaatt
     1441 tgattttctt gtgctttgat agttgataat gcatctccat ctaacactaa atttgttgtt
     1501 ggtgtcactt tgtacatagg tgcagtacct gtgttgtagt atctaatatt tgcatttata
     1561 tatgcagatt ctcctttgtt tatacttaat ccagtatttc atgattatcc attgctattt
     1621 tgaacagcag ttgaattatc tgttgtatgg taataatttg tcttgtatag tttctttaaa
     1681 ctcattaaat ttttctaatg aaatttcgtt ttgatttttt gttcttatta ctttattaaa
     1741 tgcaaatttt tctggagatt caaaatgata tacatacata ggtttatcta ttttattttt
     1801 tgatatagca tttcgaagtt ctctatattc tttttctcaa gaatttgctt ctatttgata
     1861 atcataaaaa taatttcttg tctgagaata tttgcttatc tctatagaat cttttttata
     1921 tgatcctaat acttcttttt cagatttttc aagtttttga tcttttcttt ctccttttct
     1981 ttatctttaa aaaaatcctt ctgatctttc tataggagcc ttgtaagtag tattacaaac
     2041 ttttccacta tagctttgta aatcttgtgc ataaatgtta ttaggtaaca aactacctaa
     2101 agttagatat aatatcaaca atatagatat acaattacta atacttttat gtttcctaaa
     2161 ttttttcatt tattctccct acaaatatta gtttagttaa cttttgaatt ttaatttatt
     2221 tagattatat aatctaaata agaatttttt atataaattt cataaaatat gtaggtatat
     2281 atcataaaaa tatgtattta tatgatatgt cagtacaaaa taacaactga atattttaaa
     2341 gagactattt cgtactttta tgatttaatg agctatctta tcgaatcata atctaggaac
     2401 aattgttata atatctaata gtagttatat atgatatagt cagtatgtgt tttttcacaa
     2461 tatgattatt atatagagga ttcttaggga ttactctttt tgtataaaaa agagatggtt
     2521 caaattttta tcttgagaca tctccttttt ctatttatta tgttttaata atattcttta
     2581 aaatatttct atatgtatta gatatacgac atatatggcc attactcatt ttaatattat
     2641 ttttctttag gtcgagagaa acaatatgat atttattaac tacaaaagat ttatgtacac
     2701 ggataaagca tgcatctaaa tctggtaaag actttaaact tttatagaat tcaaatattc
     2761 tagaagtagt cactaatttt attttatgtg gaatagtgct tgtttcaaaa tatataactt
     2821 catcaaatga aattttccat agtgagaaat ctgaatagat agtaaaaaaa ttagagcgat
     2881 aatttttttc tttaatgtat cttttgtgag caattttaat acaagctttt attttacttt
     2941 cagcaatttc catatcatgt tttagtataa agtccataac ttctaaccta taatcgaaga
     3001 tccctaaaat catttctata tgatttgtaa gaaatatgat tggactaata taatctgatt
     3061 ctctaatttt ttgtgctatc cataatccat cacataattc attacttatc ttatattttg
     3121 cgtctacaac tataaaatat attcttactt tatttttttc agtaagctct tttaataaca
     3181 aatttgcatt atgatataat cttacaacat cattatcaaa accttctttt attaaaatat
     3241 tatttatttt ttcttttagt ttcattccaa aacaaacatc attatcaaag attaatatat
     3301 ccactaaata ccctcctata aaaaattcaa aagtaaaaaa acaaaagtat tttatagaaa
     3361 atacataaaa taacactagg agataaataa gattaaggat agttagaatt aaggtatatt
     3421 tatgcttgtt tatatag
//
LOCUS       DAEPXW010000200         3307 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.204, whole genome shotgun sequence.
ACCESSION   DAEPXW010000200 DAEPXW010000000
VERSION     DAEPXW010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3307
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.204"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(285..542)
                     /locus_tag="KRM55_003656"
     CDS             complement(285..542)
                     /locus_tag="KRM55_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1595840.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            1122..1343
                     /locus_tag="KRM55_003657"
     CDS             1122..1343
                     /locus_tag="KRM55_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBH1595841.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            2161..2391
                     /locus_tag="KRM55_003658"
     CDS             2161..2391
                     /locus_tag="KRM55_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBH1595842.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            2404..2553
                     /locus_tag="KRM55_003659"
     CDS             2404..2553
                     /locus_tag="KRM55_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBH1595843.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            2810..3247
                     /locus_tag="KRM55_003660"
     CDS             2810..3247
                     /locus_tag="KRM55_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBH1595844.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
BASE COUNT         1336 a          422 c          355 g         1194 t
ORIGIN      
        1 ttctttattt atatagttta tttgtttatt tttccccttt atacaagcaa ttgtatcatt
       61 ttatctattt tttagccaac aaatattttc gaccattttc tttgtattct caatatatct
      121 ccagtattta acaaattttt ttatagaata tacaatgtat ttaaattaat aagtagtaaa
      181 tttagttaat ttgtctaaaa aaactttata aaacatcttc tttgtctttg ctcttacatt
      241 taacaaggct attttcatta tgtttaaaca ttattttatt atatttaaac actattttca
      301 ttgagtattc gcttaatatt gcttacacac atattatatc taatagccaa ttcattgtgg
      361 ttgactccat taaattgttt tactatatcc ctatttctag catatctaaa aagcccctta
      421 tacgtaggta tataagtatt tgttcctcca tacaacttgg caacctctat gaacttatca
      481 attccaatta tttctaccat tgcatgaaat tgaactggta tatcctccac ttttatcttc
      541 ataagttaca cctcctttaa gatattttta tagacttaac aaagttttta tttaatacat
      601 tattgactaa actatattta ttagttttat tgaatctaat aaataatttc ttagctttaa
      661 aattaatttt tgtattaact ttaataaaat ttctcataac ttataacttt gttagcttta
      721 ataaagattt taatggttta aaagtaaaat gttaatattg gacttttaac ttttttattt
      781 acagattaaa tttaataaaa tttttaacat aagctttaac atttaattta acataaactt
      841 tagtacctaa catttaactc tacacatatg aaaatccata caaaactatc tcaactaagc
      901 atgaatatat acaaatacta tttcaaaaca ctaagaacat atcttcacaa ataacttgta
      961 aactttttca tcagcaaaaa agtaaaattt ttcctataaa aatttacaca aaaaatcttt
     1021 agaaattact gtttaactcc gatattatct tagatgatag tattatagct aacaaagaaa
     1081 gtcgacaaat ctttgaaatt aaatttttag gaggtaattt tatggaagtt gtttcaacaa
     1141 aaaatttatc tagtataaaa ctaaaattgg atgctggttt tgatgataag ggtaaggcag
     1201 ttgttaaaag taaatcattt gcaaatgtaa aagcagaggc attaaatgaa gatgtttatg
     1261 ctgttgcaga agcaatagca agtcttcaag agaaccctat tgtagatatt ttaaaattag
     1321 atagtacatc attatctaaa tagtaccttt taaacgtact ctgctttaca aattaaaaaa
     1381 attaactctt tatataaaag attaagttat ataacgcact taatacgcta tagatttggc
     1441 agattataac ttcaattttg attataactt taatatatta atgctttgaa aaattaatat
     1501 attaaacgta tttcaactta aacatgttag ctattttaga tgctacccta ctttaatcta
     1561 attaattgaa ataaattaaa tattttctat atcagcaata actagagtca acaattaaaa
     1621 tactaatatt gacaattgaa acactgatac taacaagcaa aacactaata ttgacaattg
     1681 aaatattaat actaacaagc aaaacactaa tattgacaat tgaaatacta atactaacaa
     1741 gcaaaacatt aatattgaca attgaaatac taatactaac aagcaaaaca ctaatattga
     1801 caattgaaat actaatacta acaagcaaaa cactaatatt gacaattgaa atactaatac
     1861 taacaagcaa gacactaata ttgacaattg aaatattaat actaacaagc aaaacactaa
     1921 tattgacaat tgaaacactg atactaacaa gcaaaacatt aatattgaca attgaaatat
     1981 taatactaac aagcaagaca ctaatattga caattgaaat attaatacta acaagcaaaa
     2041 cattaatatt gacaattgaa atattaatac taacaagcaa aacattaata ttgacaatta
     2101 aaataccaat attaacaagc aaacaattaa aatataaatt attatatcgg aggtaattat
     2161 atggaaatta agaaaaaatt agtcatgagc tttaaaaatg taaaggataa acaagtttct
     2221 ttttctatag aaaatccaaa ggatgattta actgaagaaa atataaaatc tgtcatggat
     2281 ttgatagtat ctaaaaatat tttttcggtt ggaggatttg acctagcttc tgttgttgaa
     2341 gccaaggttg tggaaacaaa taccactcct tatgacttag ttatagaata gggggctaat
     2401 tttatggatg atagtttaca actgttaata accaatgttg gttttcctat agctctatcc
     2461 atgtacttgt tggttagaat tgagggtaaa ttaaatactt tatcaaacag tattgataca
     2521 ttatccaaaa atattttgat atttaagaag taatttgaca atatatgtaa gtcataaaat
     2581 aggtctattt gtaaaataat tagacatatt ctatgtgaaa tactaggata tttggataat
     2641 ttatccaaat atccatagta tttttttgaa ttttaccacc tcaaatttga atttcactgt
     2701 tttatttttg aatttcacta tgcttaattt gaaatttaga acgcatctag ttggactcaa
     2761 taagatataa tgctattcta atgacagtaa taaaatgagg tgatgattaa tgaaaataca
     2821 tgtcgaacaa ggtattaatt gtgatgatat tgaaataacc ataaaatgtt ctgctctaga
     2881 taataacatt gaaaaaataa tttcattatt gagtacaccg ttacttgata taaaaggtaa
     2941 aaaatcagga gagatttata aactcaatgt ctgtgatatt ttatactttg agacagttgg
     3001 aaataaaaca tttgcttatt atgaagatga tgtatttgaa attgatttaa aaatatataa
     3061 attatcaaaa ttattagcta atacatcctt ctcacgaata tctaaatcca tgattttaaa
     3121 tatggactac ataaaaagta taaaagtaat atcacataat cgcatgcaag ctactttaaa
     3181 aaacaacgaa aaagttatta taaatcgtcg ttatataaaa aatattaaag aaaagctaaa
     3241 catttaataa aaatctaaag taatttatta atatcactaa ttgcaaattt attgacctat
     3301 ttaataa
//
LOCUS       DAEPXW010000201         3202 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.205, whole genome shotgun sequence.
ACCESSION   DAEPXW010000201 DAEPXW010000000
VERSION     DAEPXW010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3202
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.205"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(275..451)
                     /locus_tag="KRM55_003661"
     CDS             complement(275..451)
                     /locus_tag="KRM55_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595845.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(505..601)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1398..1799
                     /locus_tag="KRM55_003662"
     CDS             1398..1799
                     /locus_tag="KRM55_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HBH1595846.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     gene            1796..2863
                     /gene="rsgA"
                     /locus_tag="KRM55_003663"
     CDS             1796..2863
                     /gene="rsgA"
                     /locus_tag="KRM55_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH1595847.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
BASE COUNT         1140 a          403 c          536 g         1123 t
ORIGIN      
        1 atttgcaaat ttataatttt gttaatctaa tccttcaaac taaaaaatca tttatattta
       61 cagaatttca ttttaagaga tgtttatttt cacatagata agagaattta agttctcata
      121 tttattattt gatacaaatt tacatcttta ttatatgtat tttaaataaa aaataaaatt
      181 atgaatacta gaaatctatc ttaattagct ttctaacata aggctattta aagtagataa
      241 aactaaaaag ggttctctag aaaaccaaat ctatttaatt atacttactt actaatacca
      301 tcacttgatg caaacaagat tctaccacat tttctccgta ctctagtata aaatcatcta
      361 gttgtgtatc tataaaatca caataatcat atgaactacc aatataagca gtcaacatat
      421 gtgtacatct atccatttta tctctaaaca tatatattat tatcccccta aaaaactttc
      481 ataaaaacaa aaagaatatc tctttttggc aactggctga cataactcat agtttatttt
      541 ataagcgtta gtccctatag ctttgcgtca ctaaatttct ctagttttgc cgatttagtt
      601 ttattctaca attacaataa tacaatagaa ttgcttatta ttcaatatac ttatttgaaa
      661 attaaataaa tttacaaata tgaacgttat tttatatcaa aaaaaataga ctatgcatgt
      721 agaatatatg gaaaaacttg attgtaggtt ttgtatgaaa agacagttgt tattaattta
      781 agtgagataa attgagcaac aggcataaaa tgagaaaaca aataatagca gttaattttt
      841 attattaata ctaggtgaac attaaatttc aaaataccac tagattttat agaataagaa
      901 aatgagacaa acataaatat atgaatatat taaattatac ttgaacatac ttatatttta
      961 tgataaaatt tcaataataa ttattagtga aggagtgtct tgcctgatgt cagagttata
     1021 tataatggta accaacaaat aaatagttgg agacgcatat gggttctgtt taatcagaat
     1081 ttttaagtgt atttttgata catttgattg ttgtgtctta ctctgccttt atagataact
     1141 aacattagac aacaaataat aatattacat attactttgt taaattgtgg tgtagtgggc
     1201 tttaatctgc tacactttta ttaattttac acagtattat tttgaatata attatgttga
     1261 aatagaagat actaaatttt ctagtccaca ggggttttct gtttttgtgt aggtaaatat
     1321 gtataccaca taaaaaggca gatataaata cctgtggact ttttttgtag aaaatacacg
     1381 atacggagga aataaaaatg aattataaaa atagaaaacg agcttattat caggaaaatt
     1441 cctgtatgga taactttatt tgcaaaaatt gtggttgcct tgtagttcct gaaggagctg
     1501 gtacacaaca tagaaatcat tgtccacatt gtttacatag tcttcatgta gatatcattc
     1561 ctggtgaccg tgctgcagat tgtgatgcta atatggaacc tattggagtg tgggtgagaa
     1621 aaaatggtga gtgggcaatt attcatcgtt gtacacgctg tggacatctt agttctaatc
     1681 gtattgcagc tgatgataat tcagtgaaat taatgtcaat tgcattaaaa ccactggcac
     1741 agcccccttt cccactagaa agaatcattg aaaagttgga aaaggaggaa acagaatgaa
     1801 tggtatgaaa caaatcaatt tacaagacta tggtctaaat agaaatttta ttactcaaag
     1861 tatggaatat catgatttat accttgctcg gattatctcg caggaaaaga acttttatca
     1921 agctgtatgt gtaaatggtg tactgtttgc agaggtttca ggaaagctgc gttttgaggc
     1981 tactatacaa tctgattttc ccacagttgg tgatttcgtt atgttggatc gttgcaataa
     2041 taaaaatggt aatgctatta ttcatcatgt gcttcataga aaaagcttgt ttgtgcgtaa
     2101 ggctgctgga aaggtaaatg aggagcaggt ggttgcagct aatattgaca ttgttttttt
     2161 gtgcatgtca ctgaataagg attttaacat tcatagattg gagaggtatc tgtctttaac
     2221 atgggaaagt ggagctatcc cagtagtagt acttactaaa tcagacttat gtgacaatgt
     2281 gcatcgtaaa ttacaagtag ttaattctat agccttgggt gtagatgtag ttgttacctc
     2341 atctatagag ccagatggtt ataaacagat ttctaagtat attaaaccag gctgtactgt
     2401 tgccttactt ggttcttcag gagttggaaa atcttcatta attaattgtc tgatgggtgg
     2461 agaattttta aatacaaagg aaattcgcat agatgatgat aaaggaagac atgccacgac
     2521 tagacgagag ctatttttaa tttcaggtgg tggtattgtt attgacacac caggtatgag
     2581 agagttggga atgtgggatg tttcagaagg tttagataaa agttttgcag atatagaagc
     2641 ttatttcgga aaatgtcatt ttcgtaattg tactcacacc tcagaaccag gctgtgctat
     2701 ctgggaagct attgctcatc aagaactttc gcctaaaaga tgggaatcct atcgtaggct
     2761 taaaactgaa gcagtatttg cagacaataa aagcgaatac ttagcaaaaa aagaaaagaa
     2821 atttaaaaat atctcaaaaa taaataagaa gattagaaga taagtgtagt ttttttgttc
     2881 attctatgag tctatatact attaatatat taaatttgcc atcaatttgt tactttaatg
     2941 tgattttgat ggcaaatttg gtttgtggta ttatttaaag caatttatta atttttttaa
     3001 taaagtttga ttttttatat gatgatatat acatgtgata atgtatacat atttgttacg
     3061 ataggctcct ttataaagag gtcttatgta agataagaaa aggcatattt atactaatac
     3121 ataatagagt atatgcttat gtatgataga gatgtttctt aagagcaaaa ctgcaatatt
     3181 gctaatttat aaagtaaaaa ta
//
LOCUS       DAEPXW010000202         3114 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.206, whole genome shotgun sequence.
ACCESSION   DAEPXW010000202 DAEPXW010000000
VERSION     DAEPXW010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3114
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.206"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(<1..1069)
                     /locus_tag="KRM55_003664"
     CDS             complement(<1..1069)
                     /locus_tag="KRM55_003664"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595848.1"
                     /translation="MFKFIKRKKEEQQEEKEKIERNKKLEEIRLKEQEKLKEEERIKN
                     EERIEKEIEKAYKEEEERIKNEENLRIEEERVRNEEKLRLEQERAKEEERLKNEELIL
                     QNKFREEIDRNYISITFSAINICTMHNFCCELMEKIYGDIDKSIFYKTIIEIYKIMTD
                     VNSIEEFDEILTLEKSQLLVEKIYTTHVCDISDELSIEVGNITIDNKIDNYILNESLY
                     GGTEVFNMLFTQITDSWDDLSNLDFKTLLISWFMFSYAKAFNKLLILLRYKDSFVNNK
                     ELYTITRNLYIELKEYNLVNEKLYPMYKEFYFDTFNIALDEVYFNILAGLISKEILFN
                     EIEIEDTLSNIINEIDIINKDN"
     gene            1255..2934
                     /locus_tag="KRM55_003665"
     CDS             1255..2934
                     /locus_tag="KRM55_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1595849.1"
                     /translation="MKSALYIRVSTHYQIDKDSLPFQRQELINYSKYVLGIDDYEIFE
                     DAGYSGKNTDRPAFKDMMNRVRNKEFTHILVWKIDRISRNLLDFCDTYEEIKKLNVIF
                     ISKNEQFDTSSAMGEAMLKIILVFAELERQLTAERVYSIMLSRAEKGLWNGANCPIGY
                     TYDEESKFPQIDTQESIIVKMIYDKYEELKSTSKVASYLNNNNIKTKRNGIWTSKTIC
                     DIIRNPFYKGTYRYNYRESARGKIKDEKEWIVIDNNHSKIISTEQWQHCNDIMNTNGS
                     KVSASFRKNVINTHIFGSFLVCGCCGNRFVSNLDRPRKNGYKPSSYRCSSKFKDVYCN
                     SKIITDITLGPFIFNYILNLIKVHIYGVKNIKELEKKLLQGNTFKNIIGIKQDELENM
                     YICIYVSKNQKIRHLNRNNIKKKNSNMKDTTIKLLLSEKEKFENALNKLEDLFLFSKD
                     MSKKQYLLKKVSLKENLSAINNKLEIESKKADNNSLPNDMSFLKTASNFLLSFNLLNE
                     KSVDYKRLVMNMDKQILKDFIESMIDNITIKNGIIHSIKFKNKLTNTFIYK"
BASE COUNT         1166 a          433 c          343 g         1172 t
ORIGIN      
        1 tattatcttt attaattata tctatttcat taattatatt acttaaggta tcttctattt
       61 caatctcatt aaacaatatc tccttactga ttaatccagc aagtatgtta aaataaacct
      121 catctaaagc tatattgaat gtatcaaagt aaaattcctt atacatagga tacaattttt
      181 cattaacaag attatattct tttaattcta tgtatagatt ccttgttatt gtatataatt
      241 ctttattatt tacaaaacta tctttatatc ttaataggat caataattta ttaaaagctt
      301 ttgcatatga aaacatgaac catgatatca ataaagtttt aaaatctaga ttacttaaat
      361 catcccacga atctgttatt tgagtaaaaa gcatattgaa tacttctgta cctccataaa
      421 gagattcatt taatatataa ttatctattt tgttatctat tgttatattt cctacttcta
      481 tacttaattc atcacttata tcacaaacat gtgttgtata tattttttcc actagtaatt
      541 gtgatttttc caaagtaagt atctcatcaa attcttcaat tgaatttaca tcagtcataa
      601 ttttatatat ttctataata gttttataaa atatagattt atcaatatca ccatatattt
      661 tctccattaa ttcacaacaa aaattatgca ttgtgcaaat attaattgct gaaaaagtaa
      721 tggatatgta atttctatca atttcttctc taaatttatt ttgtaaaatt aattcttcat
      781 tttttaatct ttcctcttct tttgcccttt cttgttctaa tcttagtttt tcttcgtttc
      841 ttaccctttc ttcttctatc cttagatttt cttcattttt tatcctttct tcttcttctt
      901 tatatgcttt ttctatctct ttttctattc tttcttcatt ttttatcctt tcttcttctt
      961 ttaatttttc ttgttctttt aatctaattt cttctaattt tttatttctt tcaatctttt
     1021 ctttttcttc ttgttgttct tccttctttc tcttaataaa cttaaacata ctactactct
     1081 ccatcccttt taatttcatg tggtaataat tctaaattat atacatcatc ttttaaattc
     1141 tacataaaat tataaattcc tttatcgaac ttttaaaatc tccttttatc atgttaattt
     1201 tgctatttta aacaaatctc aactcttata aactctactt agagaggtga taatatgaaa
     1261 tctgcactat acataagagt aagtacacac tatcaaatag acaaagattc cctaccattc
     1321 caacgccaag agcttataaa ctactccaaa tatgtacttg gaatagacga ctatgagata
     1381 tttgaagatg ctggatatag tggcaaaaac acagatagac ctgctttcaa agatatgatg
     1441 aatagagtaa gaaataaaga atttactcat atactagttt ggaaaataga tagaatatca
     1501 agaaacttac ttgatttttg tgatacctat gaagaaataa aaaaactaaa tgtaatattt
     1561 atcagtaaaa atgaacaatt tgacactagt tcagctatgg gtgaagccat gttaaaaata
     1621 atacttgtat ttgctgaact tgaaagacaa cttactgcag aaagagtata ctcaattatg
     1681 ctttcacgag ctgaaaaagg actgtggaat ggcgctaatt gtcctattgg ttatacttat
     1741 gatgaggaaa gtaaattccc tcaaattgac actcaagaat ccataatagt aaaaatgata
     1801 tatgataaat atgaagaatt aaagtcaacc tcaaaagttg catcttattt aaacaataat
     1861 aatataaaaa caaaaagaaa tggaatatgg acaagtaaaa caatttgcga cattataaga
     1921 aatccatttt ataaaggaac ttatcgttat aattatagag aaagtgcacg aggaaaaata
     1981 aaagatgaaa aagaatggat tgtaatagat aataatcata gtaaaataat atctactgaa
     2041 cagtggcaac actgtaatga cataatgaat acaaatggtt caaaagtttc agcatctttt
     2101 agaaaaaatg ttataaatac ccatatattt ggctcatttc tagtatgtgg atgctgtggt
     2161 aatagatttg tatcaaacct tgatagacct agaaaaaatg gctataaacc ttcatcatat
     2221 aggtgctcaa gtaaatttaa ggatgtttat tgtaattcta aaattattac agatataact
     2281 ttaggtccat ttattttcaa ctatatacta aatcttataa aagtacatat ttatggagtt
     2341 aaaaatataa aggaacttga aaaaaaactc cttcaaggta atacatttaa aaacataatt
     2401 ggaataaaac aagatgagct tgaaaacatg tacatttgta tatatgtttc aaagaatcaa
     2461 aagattagac atctaaatag aaataatatc aaaaagaaaa atagtaatat gaaagatact
     2521 accattaagc ttctattatc agaaaaagaa aagtttgaaa atgctcttaa taaactggaa
     2581 gatttatttt tattctccaa agatatgtca aaaaagcagt atcttttaaa aaaagtttca
     2641 cttaaagaaa atttatctgc aattaataat aaattggaga ttgaatctaa aaaagcagat
     2701 aataactctt tacctaatga tatgtccttc ttaaaaactg caagtaattt cttgctttca
     2761 ttcaatctat tgaatgaaaa atccgttgac tataaaagat tagttatgaa tatggataaa
     2821 caaattttaa aagattttat cgaatctatg atagataata taacaataaa aaatggcata
     2881 atacatagca taaaatttaa aaataagctt acaaatacat ttatatataa gtaataaaaa
     2941 taagctattc atgatacatt gaatagctta ttttctatgt taataatagt agtgagcatc
     3001 taaacatgtt aacttacact agaggacacc cgaaggtttg agtaaacacg agttttctct
     3061 ttccagttct gttgaagtat tcttcatttt gtctgtgtat ttgttctata tatt
//
LOCUS       DAEPXW010000203         3098 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.207, whole genome shotgun sequence.
ACCESSION   DAEPXW010000203 DAEPXW010000000
VERSION     DAEPXW010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3098
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.207"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            183..977
                     /locus_tag="KRM55_003666"
     CDS             183..977
                     /locus_tag="KRM55_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595850.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            978..3038
                     /locus_tag="KRM55_003667"
     CDS             978..3038
                     /locus_tag="KRM55_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1595851.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLKVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         1196 a          317 c          503 g         1082 t
ORIGIN      
        1 tttataatgt aaaaaaatgt tacaaaagat attataaacg aataaaaaat aataatttgt
       61 cagataaact tgtaaatttt tatgaataat ccattctaaa acaaaaaact gtgtataaaa
      121 aaggtttata tgttatattt atataaatat aacatatgaa cgagaaagga gtggtttgat
      181 aaatgattga ggtagataaa ttgtgtaagt cttttacaag ggttgtaaaa gatgataaga
      241 ataaaagttc aataagaaag ctaaagaaag taaaaactaa aaaagaagaa ttttttgctg
      301 taaataatgt ttcatttaaa gttatggaag gtgaaattgt tggaatatta ggtccaaatg
      361 gtgcaggaaa gactacatta cttagaatgt taggtggcat attaacacca acatcaggaa
      421 gtataaatat ttctggatat gattattcaa tagatagaaa ttcagcaaaa aaagaaatag
      481 gttatctctc tggaaataca aaactatatg gaaggctttc tccgagagaa cttctaacaa
      541 cttttgcaag tctatatgag atgtcaaaag aagatataga agaatcaatt gaaaatattg
      601 taaaaataat ggatatgagt gaatttatag ataatagaat tgaaaatcta tcaactggtc
      661 agactcaaag aacatctata gctcgttgtt taatacattc tccaaaagta tatatttttg
      721 atgagccaac actaggtctg gatgttttaa gtagtgcatc tattatagat tttatgaaga
      781 atgaaaaact aagaggaaaa actgttcttt actcaactca ttatatggaa gaagcagaaa
      841 ctttatgtga caagattttt atgattcaca atgggaaaat aattgcatca ggaacaccac
      901 agagtttaaa agaggaatct ggagtaaata atttgagaga tgtattcata aaacttgcca
      961 gaaaggagga catttaaatg agaagtaaga ttgtaaaata catatttaaa aaagaaatgt
     1021 tagacatatt gagagataaa aagactttat ttatgatgat tgttgtgcca cttcttttat
     1081 atcctttact tatgttatta atgattcaag taatgaatat gtctgcaagt agtatgaata
     1141 gtaaggacat taatatagct tttaataata aacctaataa ggttttagta tccatgattg
     1201 aagatgataa tttagaaaaa gatactaaaa atacttcaaa tgataaaggc aaaataagag
     1261 tgttagatgt agataactat aaaaagtcat tagaagaaaa taaaattgat gcttatataa
     1321 agatggaaga aaaaaaatca tctataaatt atcaaatata tataaattct tctcaagaaa
     1381 attcttctaa tgcactaaaa agaattgaaa ctgttttgga taaatataaa agatttacca
     1441 tagaaaaaac tttatctgaa aaaggattag atgtacaagc tactttagaa ccaataacat
     1501 atagcactgt agatgttgca aagacggaag aagtggcagg atacttttta ggtcagatac
     1561 ttccatttat attaataata ggagttttac taggttcaat atatccagca atagatgtta
     1621 tggctggaga aaaggaaaga ggtacattag aaacattatt tacactccca atatcaaact
     1681 tagaactggt tatgggaaaa tatatggcag tttctcttag tgcaatagta acagcaattt
     1741 taaacatttt atctatggga ctgactatgg catttatttt agttagtgga ggtattagta
     1801 gccaatttgg ctttggaaac tttaattatg gagacttagt cttaccaatt ataactactt
     1861 taatttgcat atgtcttttt tcaatggtag tttcagcaat aagtatgtgt gtatgttcat
     1921 tagcaaaaag ttttaaagat gctcaaaact acataacacc tcttatgtta attattatga
     1981 taccatcata tgtttctatg ataccaaata tagtattaga tagagtaaca gctgtaatac
     2041 ctgtagtaaa tatatcttta cttataaaaa gtgtattatc ttttaaaagc gatttaaatt
     2101 taatagcctt agttttagca tcaaatgtag cctttgttat attggcaatc atactactgt
     2161 ctaagatgtt caattctgag gaaatacttt ttggtaatag taagagtttt tctttcttag
     2221 agaaaagaag taatataaaa aaagggtcta taccaactgt aagtgatggt gttattttat
     2281 atgcagtagg attagttcta ttgatttatg ttggttcttt agttcaaatt aaatttggta
     2341 tggcaggtat tataatgaca caattcatga taatttcttt accgttatta tttgcatact
     2401 atattaaagc tgattttaaa gaggtattta gcttgaaagt tcctaaatta aagcatgtgt
     2461 ttgggagcat tgttctttgg attggtggat acatacttat tatgattata acacagctaa
     2521 ttttattctt atttcctcaa aatatggaag ttgctgaaag tttaaataag gctcttttta
     2581 tcaaagatag tgttttactg aatttactag caatagcttt attaccagct atatgtgaag
     2641 aaatgttttt taggggattt atattttctt catttagtaa atcaaaagat aaaaataagt
     2701 ctatcaagct agctataata tgcagtgggg tactatttgg tattatgcat atggatttta
     2761 ttagaataat tccaacatca atattaggta ttatatttgc atatagtgtg tataaatctg
     2821 gttcaatatt tgtatcaatg ttattgcatt ttttaaataa tagtgtagca gttgtgttaa
     2881 atcattatac aactggaaat ataaccaact tatataaatt tgttgaagtt gatttttcga
     2941 acttaaatgt acttaaattt gccttaattc ttctaataag tcttatatta attatgttag
     3001 gattaagagt tttagataga aagtctttaa gaaattaagt ataaagttat tatatagatt
     3061 aaaatattaa taagcactaa agtatatgaa tatatctt
//
LOCUS       DAEPXW010000204         3079 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.208, whole genome shotgun sequence.
ACCESSION   DAEPXW010000204 DAEPXW010000000
VERSION     DAEPXW010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3079
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.208"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(56..958)
                     /locus_tag="KRM55_003668"
     CDS             complement(56..958)
                     /locus_tag="KRM55_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1595852.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSEGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            complement(1008..1469)
                     /locus_tag="KRM55_003669"
     CDS             complement(1008..1469)
                     /locus_tag="KRM55_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBH1595853.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            complement(1521..1976)
                     /gene="def"
                     /locus_tag="KRM55_003670"
     CDS             complement(1521..1976)
                     /gene="def"
                     /locus_tag="KRM55_003670"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH1595854.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVIVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(1948..2211)
                     /locus_tag="KRM55_003671"
     CDS             complement(1948..2211)
                     /locus_tag="KRM55_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595855.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(2308..3024)
                     /locus_tag="KRM55_003672"
     CDS             complement(2308..3024)
                     /locus_tag="KRM55_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595856.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISFLLNLSISLLVLLQGIIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
BASE COUNT         1067 a          500 c          283 g         1229 t
ORIGIN      
        1 ttttaatttt aataaatttt aatcatcata gtaaaaaaaa tttttttata taaaactaat
       61 caaaaaaaga tatctgtaca tctcctgagt tttttaactt ttccttcatt attttagagt
      121 aactgcttga tagagaatac ttatatctaa gttcattaac cattttatac aattgatttt
      181 tatactccct attaagtgaa ccttcactat atagtattga taatttatca aataattcag
      241 gaaactcttt tttaacaaag tcaaaaaaaa cacctctagt tatacccctt aagtataaag
      301 tcccaggtaa aacataatgt acattacatt cttttgcatg tctaaatagc gaatttatat
      361 tatcaaaatc atctgtaata tatggtataa ttggcataat atgtagacca actgatgcgt
      421 tagtttttct aaattctttt aacattttaa atcgtctcat tgaatccaca ccatttggct
      481 caataagcct ttgtgtatct tcatttactg tggtaattgt agatgctaca ttgatatatg
      541 taatcctaga tagcttatca attaaatcgt aatctcttaa aattaaatct gactttgtag
      601 aaataatagc tggtgtcttg tattttatca gcaggtttaa tatttctggc ataattttat
      661 agtcagcttc tattggttga taactatctg taactcctcc tatattgatt acttctttct
      721 tccatttact gcttttaagt tgtctctcaa gtttttctac tatatttgtt tttacataaa
      781 tctcttcaaa ataattattg gagttaatgt acttatgaga gtaaatagca taacaatatt
      841 tacatccatg ctcacatcca cgataaatat ttaaatccca tttatatggc atactccttt
      901 ttaatttatt acaagctatt tcacaattta ttggaatata ttttatttta ttatacaaat
      961 aatcacctct ttatatacaa taatactata atgttaatct atagtaatta aaacatgata
     1021 tttccagacc acaattcata atctttacta tatttacaaa gtaatatatt ccattcattt
     1081 attggtattc ctccacatgt tgctttttct tctaaattat ataagcattg ctttaaatac
     1141 attttattat gccaatcatc atataaattt tctaaattta aactatgttc attagatata
     1201 tcatttgcaa aatttctatt tttccatttt aatatacttg tatatttaag ttcattaggt
     1261 ttataatttc tttttaacat ttcatcatgt acaatttttg tataaaattt aaattcatct
     1321 atactataat tcaatacttt attcactaat agatggtttg gagtaccttt tttatctata
     1381 gaacctttta tagcaagtag ctctctccat tgacttacta attgattttt aggtaataca
     1441 tcaattaaat ccttatgcca taatctcata atttaactcc ttactataaa atattttata
     1501 aattcaataa ccaatctatc ttacaatttt acatgttcaa taattttatc tgtaaaaact
     1561 ataccattta aatggtctat ctcatgacaa agacattttg ccataaaacc tgaaccttta
     1621 atttctattt tctcaccgta ttcatttaga gcttgcacta taactttttt tggccttttt
     1681 aatttacccc atacttcagg aaaacttaaa catccttcaa caacaatttg ttccccttct
     1741 tgtttaataa tttcaggatt aacaagctta ataagtcctt ctcctaaatc tataacaact
     1801 aatcgcttta atactcctac ttggcatgca gctaatcctc ctccatttgg agtattgtac
     1861 atggtctctg ccatgtcatt taatatttct cttatcttat tatctacgtt ttctacatac
     1921 ttactctttt ttcttaaaat ttcatcatca aatgttctta tctttcttat agccataata
     1981 ttctccccta cttatctgtg ctcttgattt tctttcactt tcttcaaata aaaatacact
     2041 ttcaattggt tcattaaaaa ttcttgaaat atcatatgcc aaccatattg aaggttcatt
     2101 tttaccagtt tctatagcat ttatagcctg tctagatgtt ccaactaatc ttcctagttg
     2161 ttcttgtgtc aatcctaatt tttctcttaa tatctttatt ttatttttca tatttgctcc
     2221 attcatgtaa ggttaacttt acatcttaaa tgtaacattt ttcaacatta ctgtcaagtc
     2281 aaccttacat ttatatatta aattttctta tttaactatt tttttactaa actttttaaa
     2341 taataataaa atccatatta atgatataac aattgaaata aacatataga cataattatc
     2401 ttccttaaat gccttcgata tccaaaaagt tggtaagaag aacagaatat attgtgcttt
     2461 atttaaaata aaaaatggtg ctaaaatacc catcataaaa acacctgaga atttcgtaat
     2521 taccattcct tctagtttat ttgatgataa agaaatcact aatattgata taataattcc
     2581 ttgtaataaa actaataaag aaattgataa gtttaacaag aaagaaattt tagttagaga
     2641 aaaaaagata agtagaatca tagtaataat aaatgctaag atacctggta ttccaaatcg
     2701 tgaaataaga taaccagttt taccaagcgg agttactatt aaatatcttg aaatgctgtc
     2761 atcaatttct cccaatatga ccattgtaga agcaaaaaag aacataaaag gtgtaataaa
     2821 agctaaaagt aaatcaaaca tcaagaaata cggctctaaa tttaattgat aataaaactt
     2881 gttaagtgat atattctgta ttaatggtat tccaaatttt ataaatactc cacataatat
     2941 tggagaaaca catactataa aaagcatagc atctctctta atttgttcaa actcttgttt
     3001 aaacgcattt ataatcttta tcatagtttt actccaccta cctttttcca actgctacaa
     3061 ataaaataat aagttataa
//
LOCUS       DAEPXW010000205         3022 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.209, whole genome shotgun sequence.
ACCESSION   DAEPXW010000205 DAEPXW010000000
VERSION     DAEPXW010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3022
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.209"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            16..627
                     /locus_tag="KRM55_003673"
     CDS             16..627
                     /locus_tag="KRM55_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBH1595857.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            925..1263
                     /locus_tag="KRM55_003674"
     CDS             925..1263
                     /locus_tag="KRM55_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH1595858.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1670..>3022)
                     /gene="miaB"
                     /locus_tag="KRM55_003675"
     CDS             complement(1670..>3022)
                     /gene="miaB"
                     /locus_tag="KRM55_003675"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBH1595859.1"
                     /translation="EEYFNRTGKRKLVFTQTFGCQMNEHDSEKLCSMLEEMGYQMSMM
                     VEESDLIIYNTCAVRENAELKVYGNLGQLKHLKGKNPDMKIAVCGCMMQQPHVVEELR
                     KKYKHVDLIFGTHNLYKFPQLLTESINSDKMLVDVWDVDGEVIEGLRSNRKFELKAFV
                     NIMYGCNNFCTYCIVPYTRGRERSRTPEDIINEIKELVANGTKEITLLGQNVDSYGKT
                     LENPVSFSELLRKVNDIEGIERVRFMTSHPKDISDEVIYAIRDCDKVCEFLHLPIQCG
                     SSSLLKKMNRHYTKEYYLEIIEKAKKEVPGIAFSTDLMIGFPGETEEDLLDTLDVVEK
                     VRYDSAFTFIYSKRQGTPAAKMENQIPEDIKHDRFNRVLEAVNRISAEINDGYKDRIV
                     EVLVEGRSKNNENKFAGRTRQNKLVNFEGGNDDLIGKLVMVKITEPRTFSLNGILVNN
                     "
BASE COUNT         1051 a          451 c          354 g         1166 t
ORIGIN      
        1 ttttaggagg taaaaatgat aaacgatatt aaaaataaat tcaaaaatta caaaccatat
       61 ataaatggat acaagaatat gaagagagca tctgttttaa ttccaatagt agaaataaat
      121 aacacacact atatattatt tgaagttcgc tcaaaaaatt tgaagcatca acctagcgaa
      181 atttcttttc caggtggtaa aatagaatca ggtgagactc catatgaagc tgttattaga
      241 gaaacttgtg aggaacttgg aacttttagt gacaatatag aagtaatatc aagtcttgac
      301 ctccttataa caccagtaaa gtttatcata catccatact taggatatat aaaaaatatt
      361 aataatttaa atataaacaa ggatgaagtt gaccatactt ttttggttcc tataaaatat
      421 cttttagaga atcctccaaa tacttatagt aatactgtaa aagtttttcc agacgaaaat
      481 ctaccatatg gttcaattcc aaaccaaaaa gattataaat ttgaaagtgg aagttatcct
      541 attctgtttt ataaatataa agattatgta atttggggaa tgacagcaaa aatactagaa
      601 aactttttaa attttttatc agaataacac tcataataaa tcatcaaaac ttttacataa
      661 gaaatttata aaagtttcta aatttaacaa ttctaaaata tcaataacta tattttgtag
      721 cactttttta ttttattatt gtttgaatat ttgatggttt tcaatgcaat ttcaacataa
      781 atactatgta ttagtgtata ctgttgatga attaaagtat gataatctat ttaataaagt
      841 atgaagtaaa tgattttaat gtgcctttat ggtaaaatta ctaataagta ataaaattaa
      901 ttaaaatata tggaggtgct tataatgttt gctgtaggat ttgttgttat aattgcactt
      961 gcctttttca ttttaagtgt actattattt aatggaaaag ccagtatgct actagcaggt
     1021 tataactcta tgagtaagaa agaaaaagca cgatacgata aaaaaaaatt atgtagaagt
     1081 tctagcattg ttacttttat tgtctctata atgctattta ttatggcgtt tttgggatat
     1141 agaatagaga gtggtcaaat ggacgaaaaa aaaatggttc ccttttctat aatatttata
     1201 atagtcatac tttccagtgt attttttaat atcctctact ccaacaaaaa atgtaaaaaa
     1261 taaatagttg taagttgagc agttaattat aaaagattga ctgctttttc atgtatattg
     1321 actactctta ttaaatattt taacatttaa aaatctatgt aaaaataatg aatatagtac
     1381 aaacttctaa taatgatttt acctttgtgg ttacagtcca ctatatataa tttaatatga
     1441 taacagggaa ttactaatga caactaagta aacttttata aaatataata aaacaaaaat
     1501 agatgtacaa tgaaattata tcttatatca aatttatttt tattaatagc aaaagcttac
     1561 attagcataa catatgacaa attcgcttaa aataaaaatt tttaatataa tttgttctat
     1621 agtacatcta ttttgattag tttacataat tttattattt tgtacaatat taattattta
     1681 ctaatatccc atttaatgaa aaagttctag gttcagtaat tttgaccata actaatttac
     1741 caattaaatc atcatttcca ccttcgaaat ttacgagttt attttgtcta gttctaccag
     1801 caaacttatt ttcattattt ttacttcttc cttcaactag aacttcaact attctatctt
     1861 tatatccatc atttatttct gcagaaatcc tatttacagc ttctaacacc ctattaaatc
     1921 tatcatgctt tatatcttct ggtatttgat tttccatttt agcagcagga gttccctgtc
     1981 ttttagaata aataaatgta aaagctgaat catatctaac tttttcaacc acatctaaag
     2041 tgtccaataa atcttcttct gtttctcctg ggaaaccaat cattaagtct gtagaaaaag
     2101 caatacctgg aacttccttt ttagcttttt ctattatttc taaataatat tcctttgtat
     2161 aatgtctatt catttttttc aaaaggctac tgcttccgca ttgtattggt agatgtaaaa
     2221 actcacacac cttatcacaa tctctaattg cgtatattac ttcatcagat atatcttttg
     2281 gatgagatgt cataaatcga accctttcaa ttccttctat atcattcact tttcttaaaa
     2341 gttctgagaa tgaaactgga ttttcaagtg tcttaccata agaatctaca ttttgtccaa
     2401 gtaaagtgat ttctttcgtt ccatttgcaa caagctcttt tatctcgtta attatatctt
     2461 caggagttct acttctttct cttcctcttg tgtatgggac tatacaatat gtgcagaaat
     2521 tattgcatcc atacattata tttacaaatg cttttaattc aaattttcta ttacttctaa
     2581 gaccttctat tacttctcca tccacatccc atacatccac taacattttg tcagaattta
     2641 ttgattctgt aagtaattgc ggaaatttat atagattatg tgttccaaat ataaggtcta
     2701 catgtttata tttttttctt aattcctcta caacatgtgg ttgttgcatc atacatccac
     2761 atacagctat tttcatatct ggattttttc cttttagatg ttttaattgt cctaagttac
     2821 catatacttt tagctctgca ttttctctaa ctgcacaggt gttatatatt attaaatcac
     2881 tttcttcaac catcattgac atttggtatc ccatctcttc taacattgaa cataattttt
     2941 ctgaatcatg ttcattcatt tgacacccga aggtttgagt aaacacgagt tttctctttc
     3001 ctgttctgtt gaagtattct tc
//
LOCUS       DAEPXW010000206         2980 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.210, whole genome shotgun sequence.
ACCESSION   DAEPXW010000206 DAEPXW010000000
VERSION     DAEPXW010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2980
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.210"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            434..2245
                     /locus_tag="KRM55_003676"
     CDS             434..2245
                     /locus_tag="KRM55_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1595860.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSMMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYITKK"
     gene            complement(2333..2914)
                     /locus_tag="KRM55_003677"
     CDS             complement(2333..2914)
                     /locus_tag="KRM55_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595861.1"
                     /translation="MLYLLKINQFEKSYDIGIFKNEQSIYKFIEKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
BASE COUNT         1129 a          304 c          416 g         1131 t
ORIGIN      
        1 agtaatatac caaaaaaaag gaatatattt acataatatg ataaaataaa ttcaaagagt
       61 taaattgtag gtaaatagta ttttaattat ttattaaaat atagattatg tatatgccaa
      121 atttaaaaag agacataaag acattataca aatatattat tggggtgata ttttgtaaga
      181 aaagaagtga tgcagtaaat taattgagta atttaaaaat gatttaatga taatgttgat
      241 gaatgtttaa aaagaaattt tagaaaaacg tatattgctg tttgtgttgg aggtgatgaa
      301 tttgtagaat ttatagggta taaatgatta aactatttaa gataaataca tatcactgta
      361 aaatattgat aatcattttt tataagagat tgattatttg caaattatat atattacaaa
      421 tgaggtaaca ataatgaaga aaaaatatga ttttttaatt tattctgcta tttggctagt
      481 tattattatt ctttttatat tttctctata tcatagtata gagcatatta aaattataag
      541 tcacactggt actattcgca gtgaaactca aaaggttgtt aagcaagaat tgaataatga
      601 aagaaatgat gacttgataa aacgactgga taatattctg ataaagctaa gaacaggtaa
      661 tggagaaaat ggatttcaaa gatgtgataa taaagaattt caacaaaaac taaatcaaat
      721 ggattctatg tgggaatcta tgaagaaaga aattataaaa gttagaaatg gtgcttcagg
      781 tgataaatta tataaattga gtgaagagta ttctgtgttg tctaatcaaa ttgtttttat
      841 atctgaaaaa cactctaatg caaaattgta ttcttttgct actgcactat ttatttatct
      901 tatattctca acaataagtc ttttaatttg ggaatattat aataaaaaaa ggtttaaaag
      961 aatattttat actgataatt taacaaaaat aaaaaatcag gttgcatttg aaaacagagc
     1021 gattgaaatt ttgcacaatg catctaacaa agagtatgta ctgctaaata ttgatattga
     1081 caattttaaa tatattaatg atacacatgg atatgaatat ggagataaag ttctaataat
     1141 agttgcagct gcactttcta aaacttttaa tatcaaagaa acttgtgcaa gaattggttc
     1201 agataatttt gtaatacttg caaaatatag agattctctt ttagaggata ttcgggaaat
     1261 gctaactaat gctataatct ctgaattaga tatgaatgta actcaaacta tatcttattg
     1321 tataggagct tacttagttg aaattgataa tttaggttat aaatctatca attctatgat
     1381 ggataaggca aatattgcac acaaggtaag taaaacaaga ggaatttcct ccacagtatg
     1441 gtataatgaa aatctgttaa aacagttaca aatggaaaat agtatttata attatatgta
     1501 taaagcgata gaaaatgaag aatttcatat gtatttgcaa cctaaatttc aaatatcttc
     1561 tttaaatgtt gtgagcgcag aagctcttgt aagatggttt tctccagaac ttggtttttt
     1621 atcaccagat gaatttattc cattgtttga aaaaagtgga tttattattg aattggactt
     1681 ttatatgtta aaaaaagcgt gttcatttgt aaaaaaaacg tttatgaaaa aaaatcaata
     1741 tacatatccg attgcagtta atttttcaag ggttactatt taccaaaata gtttttatca
     1801 aaggttttta gatactgtta aagaatatga aattcctttt aagtatatag agatagaggt
     1861 aactgaaagt gcttttaatg aaatatctca accagttatt tcgattttag aggagcttaa
     1921 aaagttagga tttttaattt cgatggatga ttttggatca ggatactctt cattaagtct
     1981 tttatgttct ctatctatta atggattgaa gttagataaa agcttactta aagaaacatt
     2041 taaccgggag aaagtatata gtattattca gtgtattatt gaaatgtcac atcgtatagg
     2101 catgtctgtt gtatgtgaag gtattgaaac taaaaaagac ttggaatttt taaatacagt
     2161 taaatgtgat gtaggacaag ggttttattt ctctaaaccg atagaagaaa aagaattttt
     2221 taacaaatat ataactaaaa aataatataa ttatttttat cagtctatac attgagtcat
     2281 tttatatctc gttaaatgac tcaatgtact gttatgtatt ttaaaatata aattatttaa
     2341 aacgtttttt gtacttatat agaaattctt ctatattttt tgattgttct cttatttcaa
     2401 ctgcttctat atctagtaaa taaagtatag aatcatttgt aagttcaaca tattcaccat
     2461 cttctgaacc gagtgcatgt ctctcaattt ttaatccttt ttcttcataa tatttttttg
     2521 tttctatata taatgattct cgcttttgta tgtagtcttt cacttcatta tttggaaagt
     2581 tatatgaatc cactaatgtt tcgccattta taaaagtttt ctcggtagca actttttcat
     2641 cccaacaatg gatttcttcc caagtaaaaa atatctcagt tccatctgga atgaatgaaa
     2701 acctggtaat aatatataaa taattattga aatttacttc ataatattca ggaatatctt
     2761 caaattccat atagtaattt gtataattaa aattactatt atcttttttt acaaagggta
     2821 ttttttcaat aaatttatat attgattgtt catttttaaa aattcctata tcataacttt
     2881 tttcaaattg attaattttt aataaataca acattctttc tccttttatt caaaatataa
     2941 tttttataaa tttactaatc tttagctttt ttaattatat
//
LOCUS       DAEPXW010000207         2942 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.211, whole genome shotgun sequence.
ACCESSION   DAEPXW010000207 DAEPXW010000000
VERSION     DAEPXW010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2942
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.211"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(77..547)
                     /locus_tag="KRM55_003678"
     CDS             complement(77..547)
                     /locus_tag="KRM55_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH1595862.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
     gene            complement(1417..1806)
                     /locus_tag="KRM55_003679"
     CDS             complement(1417..1806)
                     /locus_tag="KRM55_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1595863.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT          909 a          544 c          169 g         1320 t
ORIGIN      
        1 aaatactagt cctatatatt atcttgaatt agttctatta caattaattt ctactaaata
       61 attataattt aaacaatcat tccttactat tttcacactg ctttacaaat ttaattggat
      121 gttgaattat tttagaagtt tcttctacag agtatccctc agataaatat cttctagcta
      181 taacttccat agactctcct atctcaataa tatgcttatc cgggtcataa atacgcacta
      241 ctctttgttg ccattcatgt tttagtggct tatggacaaa ctctacatct ttataataat
      301 tgagtttttc aataaattcg tcaaaatcat caacctcaaa ataaagttcc atattatttg
      361 atttttgtat aattgtatct ggattaatcc ctgtaagcca tgcgaagtct tcttgtatag
      421 caaatcctcc tttaaatgtt acatttttgc ctaagtccaa ttcaatttct tgctcaaata
      481 attctttata aaattttttt gatacttcaa tatccttcac tgctaataat gaaacctgat
      541 atttcataaa ttttcctcct aattttttat ttctattttt tcagtatctt ctattaacat
      601 ttttttctct atctcttcag taccttttat taatccttta tttttacttt tttagcatct
      661 tctattaaca cttttgtttc tacctattca gtatcttata tcaatctttt attttttcaa
      721 tatcttctat taacactttt atctctatct attcagtact ttctatcaat cttttgtttt
      781 tatgttttca atatcttcta ttaacacttt tgtttctacc tcttcagtat cttatatcaa
      841 tcttttattt tttcaatatc ttctattaac acttttatct ctatctattc agtactttct
      901 atcaatcttt tgtttttatt ttttcaatat cttctattaa tacttttgtt tctacctctt
      961 cagtatctta tatcaatctt ttattttttc aatatcttct gttaacactt ttatctctat
     1021 ctctttaata tcttatatta atcctttatt tttatttttt caatatcatc attaattcct
     1081 atttatttta tcatcttaaa tacgaaaaca ctgtgtcata tttgcaaaat atatattatc
     1141 atctatatta aagcttcaca atttatattt aaaaattctc tttaattaca ctacctctat
     1201 ttaaaaagct accttaatta tacttataag taaaggtagc tttttaaatt taattaaata
     1261 gaatatccac tattaattta tatttaattt atttagattc acattatagt atcataatcc
     1321 acttataatc atttgtcata ttacttaagt agactaatat attacataaa tacacttaca
     1381 tacactttat attgatgcta taagaaatac gtttgcttat acgtctttct cctcttcttt
     1441 tagatttttt atccactctt caataagtaa aatatcatct ttgctcaaat taatattttc
     1501 atgtaatgac aacaataaac tttttataga agaatcatga atatttctaa aaaaatctct
     1561 tgtctcaact cctatgtatt ccttttcttt aattaaaact tcataatgcg tatatttatc
     1621 tatcttttga gaatttagaa atctttttac tactaatcta gataaaagag tcaaagttgt
     1681 cgtttgtttc cattgatatt tttgctccat tcctaaaaca atatctctag atgttacttt
     1741 ggaatctgat ttccatataa atttcattat ctttaattct gattgtggca acttttttat
     1801 agtcatgata aaaccttgct actcagaata tagacaagca atatccataa taaaattttt
     1861 cgattaaata catcttatac ggatttatat aagctcagac ttataagata tttttcaatc
     1921 ttaatcctaa atttagctat ttgtacacgg taaatatata taaataatgt caaaattctc
     1981 ttgtattata ttgcttaatt ttatgaaata ttttgtactc agctatctat tttggatact
     2041 tgtccagtag ctctcctttc ttttaaactc tttgatttta aatatttgta tttcagtaaa
     2101 tcctacttcc taaatttttt atttactaca acttattact gaacttccta cttcctaaac
     2161 tttttattta ctacaactta ttactgaact tctcacttac taaatttctt acttactata
     2221 aattataact aaacttctca cttactaaat ttcttactta ctataaatta ctactaaact
     2281 tcctactttc taaatttctt acttgctaca aattattact aaacttccta ctccctaaat
     2341 ttcttacttg ctataaatta ttactaaact tcctactttc taaatttctt acttactata
     2401 aattattact aaacttccta ctccctaatt ttcttactta ctataaatta ttactaaatt
     2461 tcctactttc taaatttctt acttactaca aattattact aaacttccta ctccctaaat
     2521 ttcttacttg ctataaatta ttactaaact tcctactccc taagtttctt acttgctaca
     2581 aattattact aaacttccta cttcctaaat ttcttacttg ctataaatta ttactactaa
     2641 acttcccact tcctaaattt cttacttact actacttata actaaacttc ccacttccta
     2701 aatttcttac ttactaccac ttataactaa acttcccact tcctaaattt cttacttact
     2761 accacttatc actaaacttc ccacttccta aatttcttac ttactaccac ttatcactaa
     2821 acttcctact ttctaaattt cttgcttctt aagaataatg ttaattttaa ttttaagatt
     2881 atagttttta ccttgtttaa ttgaaacatt ctatataatt atatccttct attttagagt
     2941 tt
//
LOCUS       DAEPXW010000208         2860 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.212, whole genome shotgun sequence.
ACCESSION   DAEPXW010000208 DAEPXW010000000
VERSION     DAEPXW010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2860
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.212"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            70..2427
                     /locus_tag="KRM55_003680"
     CDS             70..2427
                     /locus_tag="KRM55_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBH1595864.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2513..2830)
                     /locus_tag="KRM55_003681"
     CDS             complement(2513..2830)
                     /locus_tag="KRM55_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBH1595865.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1066 a          325 c          474 g          995 t
ORIGIN      
        1 aaattgagaa ttttataata tatttgtaga tttgagtata aaaaagtgct aagttgaaag
       61 gagtaaaata tggataaggt taatttagaa aggtatagtt gtgatataaa tgttggttta
      121 aataaaaatc aacttcaaag tagaatagat gataatttaa ttaatgcatt tgataatgga
      181 aaaaccaaaa catataaaca aatttttaaa gacaatatat ttacactttt taatctcata
      241 aatattgttt tagtctgttt attagtttca gttggttctt ttaaaaatac cttatttata
      301 tttattgctg taattaatac tattatagga gtaatacaag agataagagc taaaagatta
      361 ttggacaatc tatctgttat agtttcaaat aaggtatctg tcataagaga aaaagagaaa
      421 aaagagattg atgtacaaga attagtatta gatgatatta tgattttaaa aacaggtaat
      481 caaatttgtg cagattcaaa agttttaaat ggaaaattag aggtaaatga gtctttggtt
      541 acaggtgaat ctgatattat tataaaaaat aaaggcgatt ttttatattc tggaagtttt
      601 gtagtttctg gagaagcttt tgtaagagtt gaaaatatag gaaaagataa ctatgcaaat
      661 aagatagcta atgatgcaaa gatttctaaa aaacataatt ctcaacttag aaattcatta
      721 aatgcaatat taaaaattgt aggtataata ataattcctt taggaattat attgtttgca
      781 aaacaacatt ttggaaatgg agattctata gctacatctg tagtaggtac agtggcagct
      841 gtaaatggta tgataccaga gggattaaca ttacttacga gcattgctct agctgtagga
      901 actataaaac ttgctagtca taaaacttta gtgcaagaac tgtactgtgt agagactctt
      961 gctagagttg atacactatg tcttgataag acaggtacaa ttacagaagg taaaatgcaa
     1021 gttgatgata tagtaatgtt ggaagaagtg gatattaatg aaataatggg gaatatatgt
     1081 aattctctca aagatgataa tgcaacacta aatgcaataa gagataagta taatgtttta
     1141 gatacgtata aagctaagaa tttaatacca ttttcttcag aaagaaaata cagtggggtt
     1201 acctttgaaa ataaaggtac atatttatta ggtgcatttg aatttatatt taaggaaaaa
     1261 aataaaaaac ttaggataga agttgaaaga tattctaaaa aaggaaacag agtaatagtt
     1321 ttagctcata gtgattctta tatggaagat aataatattc ctgaagatat aaagccacta
     1381 gcttttatat tgatattgga taaaattaga gatgaagcta aggaaacttt agaatttttt
     1441 tacaatgaag gtgtagatat aaaaattata tctggtgaca atcctataac agtaagtgag
     1501 gtagctagaa aagcaggtct taaaacagct agtaatttta ttgatgcaac aacacttaaa
     1561 aatgatagtg atatatacaa agcagttgat aaatacagtg tttttggaag ggtaagccca
     1621 caacagaaaa aacaaatgat tttagcatta aaaaaacaaa atcatacagt agctatgact
     1681 ggagatggtg taaatgatgt gctagcactt aaagaagcgg attgtagcat tgccatggca
     1741 tctggaagtg atgttactaa gaatgtgtct aatttagtct tattagattc aaactttgca
     1801 tcaatgccaa aggttgttat ggagggaaga aaagtaatta ataacattca aagagcatct
     1861 tctttgtttt tagtaaagac aattttttca ttcttcttgt cgttattaac attattcttc
     1921 ttcagtagac agtatccatt tgttcctata caattatcac tcattggggc tgtaacagtg
     1981 ggtataccat cattcttctt agctcttgaa gcaaacaaaa gtagaatttc aggaaatttt
     2041 ttactcaata tattaaaaaa tgctttacca ggagcactat gtgtgacagt aaatgtaatt
     2101 attgtttaca atatagttga atatttaggt tatagttcaa gtgtattttc cacaatgtgt
     2161 gctatattaa ctggtgtatg tggtctttta atattaagac aacaatgttt gccatttaat
     2221 aaagaaagat tatttttaat agtaagtatg actattgcat ttgttattgg gattctattt
     2281 ttaggtggat tattctcatt tgtagcattg agtagagaat taattctcat aactatggca
     2341 ttagcaatat taatgccaat tatgataaaa gttatgttat ttgtcttaga tgagatatta
     2401 gagacaattg ttccagattt aaattaattt taaaatgata taaataagag cagttttagt
     2461 tgaactgctc tttttagatg tgtttaattt tatgtaagaa tatgtatttt tattaatcag
     2521 ctatatatga gcaacagtag tcaacaactt cattaacctt taagtcaaaa cttgaatcac
     2581 taggaacatt aaatttttgc ccttctttat aagttacaaa ctcattgctt ccaggcagtt
     2641 ttacatccat acttccagca agcatctcca ttatttcttc ttctctagta gaaaaagtgt
     2701 attctcctgg caacattaat cctaaagttt ttctttctcc attaggcagt attattactc
     2761 tgctacttac cttaccatca aaataaacgt ttgccttctt tactgcagta acattcttaa
     2821 attcactcat tagataaaac ctccaaaatt atttgtacat
//
LOCUS       DAEPXW010000209         2832 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.213, whole genome shotgun sequence.
ACCESSION   DAEPXW010000209 DAEPXW010000000
VERSION     DAEPXW010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2832
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.213"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            246..1169
                     /locus_tag="KRM55_003682"
     CDS             246..1169
                     /locus_tag="KRM55_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBH1595866.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1144..1971
                     /gene="panB"
                     /locus_tag="KRM55_003683"
     CDS             1144..1971
                     /gene="panB"
                     /locus_tag="KRM55_003683"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBH1595867.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            1990..>2832
                     /locus_tag="KRM55_003684"
     CDS             1990..>2832
                     /locus_tag="KRM55_003684"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBH1595868.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELN"
BASE COUNT         1124 a          337 c          461 g          910 t
ORIGIN      
        1 caaaaaactt atattttata aatatcataa tttttttact gatattttat tatataaatt
       61 ttatagaatt aattgtcaat tttttatgaa aatggtaaga tatttatgga tggtatcttg
      121 ttataagaac tatactttaa atgtttttaa ttattttgtc ttatgtaact catatcctca
      181 ggaatgagat tagaaattaa gatgttgtat cacaaagtgg aggtgatact attaaaatag
      241 gctttattgg ttctggaaaa gttggaacat ctttggcaaa ttatttttta tcaaaaggtt
      301 attgtgtttc aggcttttat ggaaggaatc aattatcttt attagaatca acaaatttaa
      361 caaaaacaaa gatttacagc aatttgaaag atataattta tgaaaacgat atattattta
      421 ttacaacatc agatgattct attgaaatta tagacaaaaa actttccaaa tttaatttaa
      481 aacataaata catttgccac acaagtggct ctttaaaatc tagtatattg ttctgttcaa
      541 aaaaagcagg tgcattaatt tattctatcc atcctatatt tgcattttcc aataaaaata
      601 ccaacataaa aaaaatgaaa gacatttgtt tttccataga aggtgataat gaacaagatg
      661 atttagttat tcaaaatttc atagatgatt tgggaaacca attttttata agagataagg
      721 atacttcatc cacttatcat ttagctaatg ttttagtttc aaatttagta ttatctttac
      781 tagatatagg agtaagttac tttattaaat taggtttatc tgaagaggaa tctttaaaag
      841 ctatcagtcc tttagtaaaa aaaaacatag aaaatatact tgataatggc tttactaaag
      901 ctcttactgg tcctgtttct cgtggagata taacaccaat aaggaaacat ctatctgtat
      961 tggataaaaa agatgaggat atttacaaaa tactatcctt aaacctacta aaaataattg
     1021 ccttaggaaa tgacaattca ttaaaaggta taaaaaatat tactatagaa aatgcaatcg
     1081 aaaatttaat aagtaaatct gaaaaataca aagaaattta caaactttta ggaggaaaaa
     1141 acgatgaaaa ataccataca gacttttaag aatgctaaat atgaaggaaa aaaactatct
     1201 atgcttactg cttatgacta ctcaattgca aaaataatgg atgagtgtga tataaatggt
     1261 attttaatag gagattcatt aggaatggtc ataaaaggtg aagaaaacac tctatctgtt
     1321 accatagacg aaattatata tcatacaaaa gctgtaaaaa atggtgtaaa aaatgcctta
     1381 atcgtaagtg atatgccttt tctatcttac catgtttcta tagaagatgc agttaaaaac
     1441 gctggtagac ttataaagga aggaggagct catgctgtaa agttagaagg tggctcaaac
     1501 gttataaagc aaatagaaag cattgtaaat gctcaaatac ctgtaatggg gcatttagga
     1561 ttaactcctc aatcagtaaa ttcatttggt gggtttaagg ttcaaggaaa taccagtgaa
     1621 acagcaagac aacttattga agatgctaaa ttaatagaaa aagcaggtgc attctctatt
     1681 gtccttgaag gagtgcctac gaaaatagct gagatggtaa ctaattctat ttcaattcct
     1741 acaataggta taggggcagg aattaactgt gatggacaaa ttttagttta tcaagatatg
     1801 ttgggaatgt ttggagattt tgttcctaag tttgtaaagc agtatgcaaa tataggagat
     1861 ataatgaaag attcaattaa aaattacatc ctagaagtta atacaggtgc atttccacaa
     1921 gaaaaacaca gcttttcaat aaatgaatct gagttagaaa aattatacta atattaagga
     1981 tggtacaaaa tgcttgtaaa agaaattaaa ttactaagaa atataatcaa agattggaga
     2041 aaacatggct attctatagg ccttgttaca acaatgggat ttttacatga aggacaccaa
     2101 agtcttataa aaaaagctgt aaaagaaaat gataaagtag tagtgagtgt atttgtaaat
     2161 ccaactcaat ttggaccaaa tgaagatttt aatagctatc caagagatat agataaagat
     2221 tttaaatatt gtatggatag tggagcaaca gtagtcttta acccatcacc agaagaaatg
     2281 tatttaaaag gtaattgtac taccattaat gtttctggac ttacagattt tctttgtgga
     2341 gctaaaagac ctgttcattt tggaggtgtc tgcctagttg tttcaaagtt tctaaatata
     2401 gtaacacctg ataaagctta ttttggagag aaggatgccc aacaattagc tgtaattaaa
     2461 agaatggtca aggatttaaa catagataca gaaataatag gctgtcctat aattcgtgaa
     2521 aatgatggat tagcaaaaag ttcgagaaat acatatctct ctgaggaaga acgaaaatct
     2581 gctctaatat taaataagag cttaagttta gcaaaagaag aattagtaaa aggcaatcta
     2641 aatccagaga atataaaaga attaataaca gctaaaataa attctgaaca cttagcaaaa
     2701 atagactatg ttgaaattgt agatagtgag acattacaac ctgttaagca aatagaacat
     2761 tctatacttg tggcaattgc tgtgtttata ggaaaaacca gactaattga taattttaca
     2821 tttgagttaa at
//
LOCUS       DAEPXW010000210         2771 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.214, whole genome shotgun sequence.
ACCESSION   DAEPXW010000210 DAEPXW010000000
VERSION     DAEPXW010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.214"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(23..595)
                     /gene="mobB"
                     /locus_tag="KRM55_003685"
     CDS             complement(23..595)
                     /gene="mobB"
                     /locus_tag="KRM55_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBH1595869.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(579..1760)
                     /locus_tag="KRM55_003686"
     CDS             complement(579..1760)
                     /locus_tag="KRM55_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBH1595870.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(1971..2705)
                     /locus_tag="KRM55_003687"
     CDS             complement(1971..2705)
                     /locus_tag="KRM55_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595871.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
BASE COUNT          864 a          497 c          225 g         1185 t
ORIGIN      
        1 atataagaag aacatcttaa aattattctt ttaatatgtt ttttatttca acattgctta
       61 tacttaaaat ttcatttttt atacaagact ctatgtactt tgatatattt ttataatcat
      121 ttaaattaaa ctgttcaata ttcaatttat attctatatc actgacaata cctatcaaat
      181 cagacttatt agataaaata tcctcatact taccttttct agttacttcc aatcttttaa
      241 atctataatt tttatatcct tctatgataa tcaagtccat atcttcatat aattgaatca
      301 ttttatataa tggattcttc tcttttagtt cttcaatata tgctactcgt ttatctgata
      361 ttatacagac ttttctcgcc ccagattttc tatgtttata agtatctttt ccttcctcat
      421 ccatatcaaa atcatgacag gtatgtttaa taactccaac acgataccct tttttattta
      481 attcttttat tatgccttca atcaacgtag ttttacctac tcctgaatat gagacaactg
      541 acaatatatt atacataaaa ttgtgtcctt tcataaaact atctaataac aacatccact
      601 aattgatttt cttttattgt ctcattcttt ttaatcttaa tcatacaatt acttcttaga
      661 gttgcagata gtctagcttt tgcatctttc ttatcattta gctctacata caatttacct
      721 tcacttgtat atagttttcc acttacaaat ctatctttat ttgaaagttt attaaattct
      781 cctttaaata tagcttttat atgatgtgtt cccttcttat atgttaaata ctcaataaca
      841 ggaactatca cattatcaaa taccactatt gctgcatgtg gattaccaga aagaccaaat
      901 aatagctttt ctcccaatgt acctacataa caagctccac caggtttaat gtttatcttc
      961 caaaataatt ctgttgcccc tatttttttg aatacatctg gaattaaatc tttatctcca
     1021 acagaaacac cacctgtggt aattaaaaaa tctacactct gtaacatatt ctttaccttt
     1081 ttttctaact ccaatatatc atcagaacaa ttgcatattg tatctgcttg tattccaagt
     1141 tttaataatc ttgaatataa ggtatatcta ttactatcgt atattttacc attctctaaa
     1201 gtctcattta tatcttgtag ttctgtacct gtattcaaaa ttccaacttt taaatcatca
     1261 taaacagtta ctttggatat tccaagactt gctaatactc caataccatc atatcctata
     1321 ttctgatttt tattaataat caattgcccc ttttttatat cctcaccctt aaatatgtaa
     1381 ttatcgtatt cctttaattt tatatttaaa gttatcatat cacctataac tgttacatct
     1441 tcttttttta ttacacaatt tgcaccctgt ggtatctttc caccagtcat tatcttcact
     1501 gcttcatttt tatttaatac cctattaaat acatctcctg catacaaagt ccctataacc
     1561 tttaaatttc tattttcaga atttgcatta tatgcataac catcataggg tgacctatca
     1621 aatggaggac tatcaattgt tgaatatata tcttctgcaa ctaccttatt tactgcatct
     1681 ataagattta ctatcttgac cctgtttatt ggtaaaacat ttttttcaat aatttttatg
     1741 gcatcttcta attctatcat tttaaatact ccccaatata ttttttattt aagatatttc
     1801 tatgtaatat attatagatt ataaaagttg gaaatacttt tatcttatat ttaattataa
     1861 ctaatagtta tctataagtg cagttcaaat tttataaatc taataaaaaa actgttccca
     1921 gctagaaatt tccttctatc ttgaaacagc atcatatgct ttagaatatt ttattctaat
     1981 aaagttcctt ttattatttt tacaatttta tcactttcaa tagtttttat agattttatt
     2041 ttgttatcca caatacttat tgtaagtacc tcttttttta atattttgtt atcttctttc
     2101 aatctataac tcttaactac tttactacct tcatgattat atgctgttaa atcataattc
     2161 gcatctccta caatttcatt tattctggaa tcttcaacac caacatactc tcccaggtca
     2221 atatgtctaa aattttctag tgatacagcc gatttttcat ggtcactttt ttcaatcact
     2281 atactagatt cagcatcaat gactgatata ccttgtgatg agaaagaatt ggtttcaaca
     2341 ttgacaactt tattttcgtt aatatcaaca tataaagcac ttccatctag ttcatcattt
     2401 ccagtatatt ttggataaac taatgtcata taacttgatg tatttatatc ttgcattgta
     2461 tttgattctt ttaaaacttt aggttttata taataaaatg tattataagg tatacccata
     2521 ttctttataa tgtacttata atctttattc ataatttcat taacatcatt ttgaactttt
     2581 gtcatagttt tttgctgtgt tgctttactt gctacttgat ttttctcttt agtattttct
     2641 ttatgacatc caacaagtat aatacctaaa atagttacac aaactaatga cctttttaac
     2701 ttcataaatc aatcctcctt tcttaaattt tatagtattt atctatatct caatttacag
     2761 ttatctcttt t
//
LOCUS       DAEPXW010000211         2753 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.215, whole genome shotgun sequence.
ACCESSION   DAEPXW010000211 DAEPXW010000000
VERSION     DAEPXW010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.215"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            45..908
                     /locus_tag="KRM55_003688"
     CDS             45..908
                     /locus_tag="KRM55_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBH1595872.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            975..1964
                     /locus_tag="KRM55_003689"
     CDS             975..1964
                     /locus_tag="KRM55_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBH1595873.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            2056..2667
                     /locus_tag="KRM55_003690"
     CDS             2056..2667
                     /locus_tag="KRM55_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1595874.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
BASE COUNT         1142 a          270 c          515 g          826 t
ORIGIN      
        1 caaatataat aagagagatt tatatttagg aggaaaatga taatatgaaa ttttttaaag
       61 tcgatacaaa agctaaagtt ttaagatatg tatttgtttt aacattgact ataatggctg
      121 ttttggcaat taaacatgac tataaatata ataatttaag gaaagatgct tcaattaatt
      181 taaatagtaa taaggaagca gtgactgtta tgagtaacca gtcattacca aagggtaata
      241 caaatagtaa acaaacttta tcagtaagta caataggaag taaaacaata gtgaaaaatg
      301 atgagtattt agaaagtact ataaacatgc ctgtaataac aaattcaaat aaaattgttg
      361 aaaggtctac aaatgataag ataaaaaatg acatatttga attttataat aaatcatata
      421 aagaagcaaa gcagtatctt aaggataatc ctgacgagaa aaataagttt gttgcaaatg
      481 tagactttga acttaaaaag aatactgatt ctgctcttag tataaaagtg agatattaca
      541 cttatagtgg tggagcacat ggattttatc aagatatagc atataatgtg gatatgagaa
      601 ctggaaaatt tttagaatta atggacttgt ttaaggataa tactaaatat aaagaagtta
      661 tagatgaaga aattaaaaga caaatagctg aacttgaaaa aaaggatgaa gaaaatatcg
      721 gaatatataa ttttaaaggt ataaaagaga atcaaaactt ttacttgcaa gatgagaatc
      781 tagttgtata ttttgattta tatgatataa ctccatatgc agcaggaata ccagaatttt
      841 caataaataa agcgttgata agttctatgc taaaaccaga gtatgtagat ttatttgatt
      901 tgaaatagaa gattaaatta aatgttatgc tataatattt agcatagaga cttattaaaa
      961 ttgggggtat aaaaatgcta cttttaaaaa aagacgacat aaaaaaagta tttacaatga
     1021 gagatgcaat tgaagctgat aaggaagctt ttagaattta ttgtgaagga aagagtgtaa
     1081 atcctttgag aaccaatata tctgttccaa gtcaagatgc tagtatgtta tttatgccag
     1141 gatacgtaga agaattaggc tgtgggggaa taaaaattgt atctgtattt cctaaaaatg
     1201 ctcaaaaagg caaaccagta attccagcaa cagtactatt attagatgga gaaactggag
     1261 aagttagtgc agtattggat ggtacttatg taactcagat tcgtactgga gcagcctctg
     1321 gagcagctat agacgtattg gctaaaaaag attctaagat tggagctttg ataggtctag
     1381 gaggacaagg tgagccacaa cttgaagcca tgatagaagc tagaaatttg gatgaggtaa
     1441 gagtttttag tagaaacaag gaaagtagag aaaaatttgc agaagaaatg aacttaaaat
     1501 taagtaaata taatactaaa atagttgcag ttgaatcatc tgatgaagcc atagataacg
     1561 cagatgtgat agttttagct actccatcaa aacaaccagt acttaatgga aacttagtga
     1621 aaaaaggagc tttaataagt gcagtaggtt catatatgcc agatatgcaa gagttgtgcc
     1681 caaactgttt aactagagcg tctaagatat tttttgaatc aacagatgca gttttatctg
     1741 agtcaggaga tatattaatt ccattaaaag aaggtaagat aagtaaagat gattttagtg
     1801 gtgatttagg gaatgttata aacggaacta ttcctggaag agaagatgat gatgagataa
     1861 ttgtatttaa aactgttggg ataggtgtac aagatgtcgt aacagcaaaa agaatatacg
     1921 ataaagcaaa agaaaacggt attggaatag actggaagtg gtaaaatatt caaaataatt
     1981 ctatagttag acaaatttat gttataatgt tgataaataa attttttatt attttaattg
     2041 agggaggatg tttgtatgaa aatggtaaaa aagttaatat tatctacgat tatggctcta
     2101 gttttagttc taactatagg gtgttctaat gcagaagaaa aagtaaagtc gaattttgaa
     2161 gctaatttag ctgcattaga aatgtataag tatgatgaaa aaggaatttc tgatgcatta
     2221 acagaagctg aatataaaca gattcaaact tataacagca aggacaaggt ttcaatgatt
     2281 gctcaattga cacctcttta tggtaaagaa aatgctgaaa agatatacga aacaattgtt
     2341 aaattaattc aaggtgttga aaagacagta acagtggaat cttctagtaa ggataagata
     2401 actttgaaag ttgtaagtaa agctttagat actagtaaag taatgagtga agcgaacact
     2461 ttagtaaaat cttatgtaac tgatgaaaag aattacgata aaaaagaaaa agaagttcaa
     2521 gatgatatga caaaaatgat tatagacctt tacaataaga aaccaactaa ggaagttaca
     2581 actatgatta catatactaa aaaagatggt aaatggcaac cacctagtaa tatacaaaag
     2641 ttatgtgaag gaatatatac aatttaattt attttaaaga cacaaaacta tcttttaagc
     2701 atataataaa atgtttggaa gatagtttat tttattttca aagtataaat tat
//
LOCUS       DAEPXW010000212         2702 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.216, whole genome shotgun sequence.
ACCESSION   DAEPXW010000212 DAEPXW010000000
VERSION     DAEPXW010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2702
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.216"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(220..1032)
                     /locus_tag="KRM55_003691"
     CDS             complement(220..1032)
                     /locus_tag="KRM55_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1595875.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(1108..2526)
                     /locus_tag="KRM55_003692"
     CDS             complement(1108..2526)
                     /locus_tag="KRM55_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBH1595876.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
BASE COUNT          944 a          484 c          277 g          997 t
ORIGIN      
        1 tatttataaa gtctttaata aaaatttata aatagagcat ctttagaaaa ctattataat
       61 aaaaaaataa gaggctgtct aaaaatatag ataagccttt tttcataatc gtaattataa
      121 aaatatactt gatttcatat gaaaaagagt gtctcataaa ctaaaatgtt tactttgaga
      181 caccaccttt tttattctta tttatacttt gtagacatat tataacatgc gtttcactgg
      241 tatctgaact tctgtcaacc agtcttcttc actctcttta ttccatatac catctatata
      301 agattctcta ggatttccaa ccactttata tttattgtcc tctatccatt taaatgcatc
      361 tgcgtaagtt tttcctaatg ttgaatatgg accattgtgt aatatacaaa ctgcattttc
      421 aactgcatct aattctttaa attttaatat atccgtatct tcctttaaat catttatagc
      481 ttgacacatt tcaacatcca tatcagtctc tctatattca ccatcatgat atatattaaa
      541 acaataatca ggaactgcac atgtacaccc tgttttcatc atttcttcag ccattacatt
      601 tggaaataga ttaaaaagtt catcataccc ctttaacact tttctcatag aagcaacttt
      661 aacttttggt aaagacttaa taattacatc attcatattg acttctcctt tcaaattcat
      721 aaggtaatta cgtagtttaa ttattttata ttcttcactt ttaattacat ccaacatttc
      781 tttttcttta ttcattaaaa tattttcaac ttcttcagga ttttctacag ctttttttat
      841 ctcagctaat gataaaccca tttgttttaa agttattatc tgatgtaatt taggtaattg
      901 ctctgttgta taatacctat attttgtaaa ttcatctaca tattctggtt ttaacaaccc
      961 tatatcttca taatacctta atgtctttgt agttatttta tttattttag aaaacattcc
     1021 tatagaaaac atctcatcac ctgcgcatta gatttgatta atttaagttt aaactttccc
     1081 cttaggttaa agtcaataca aaataaatta taattgtatt aattcttcaa ttctatctcc
     1141 actcaatacc aaaatatccc ctgtttttat aatggttgaa cctttaggta ttaaaacctg
     1201 ttcctttctt tttatcataa ctattaatat atcgtctggt atattagaat ctattatact
     1261 cttattagcc catttattac cctcatcaac atttacttcg ataagtttag agctaatttc
     1321 tccatcataa tcattaaatg tttttaatac aggtgtatta tcatcaacta aatccaactt
     1381 tctggctaca gttggtatca atgaaccttg tattcctact gaaagcaacg ctataaaaaa
     1441 tattatatgg aatatgtcat tctctatggc tactccttga gtaacagcat aaattgcaaa
     1501 aactactgaa gccgcacctc taagacctac ccacgatatg aataattttt ctttatttga
     1561 gaatttaaat tttgctagaa ctataaatgt tgctaatggt cttgcaataa ctatcatgaa
     1621 tatagatatg gccattgcta taccaaatac atttggtaac ttagaaggga aagataacaa
     1681 tcctaacata aagaataaca ttatttgcat aatccatgaa attccatcaa agaaatgaac
     1741 caaacttttt ttaagaggta tcctactatt tcctataata atacctgaaa tgtaaacact
     1801 taaatatcca tttcctccaa gatactcgct aaatgcataa gaaagtattg caatagctgt
     1861 tataaatata gtataaaatc cttctatctc gaagtttgaa tgtcttaaaa tataaacaga
     1921 taattttgct agtataaatc ctatagctaa cccaaaagct atttgtttta ttaccattgg
     1981 tgcaataagt tctaccccag aattattcat caatgtcaaa agaattagtg tcagcatata
     2041 cgctattggg tcattacttc cactttcaac ttctaataat gatgcaagtg aaccctttaa
     2101 gtttagtttt tgagaacgca acacagcaaa cacagatgca gcatctgttg aagctgcaat
     2161 tgccccaatt aataaacctt caagtaaact agttcctatt accatgtggc aaaacatacc
     2221 tgtaacccca gccgtaatta ttacacccag tgaagacatt aatatagaag gtatagcaac
     2281 aggtttagcc atattccagt ttgttccaaa ccctccaaaa aacattataa atattagtcc
     2341 aatagaacat aattgttttg tcagttcata gttatcaaaa tagattccta ccatcccatc
     2401 agacccaaat aacatcccta gtaagataaa aatcaataat attggtactc caaatttata
     2461 caataccttg ctagaagtta tacaaatcaa tagtactaac ccacttataa tcattaattc
     2521 tgtcatagca tcaactccat ttcatataaa ttttgtagat taatttacat ctacaatttt
     2581 attacttatt caaatataac atgacataaa ttttataagt tatggtacat aaagttcaac
     2641 aaaaatttca caatacatta aaatgtgagt gttatactta aatttatata tttgttttaa
     2701 tt
//
LOCUS       DAEPXW010000213         2647 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.217, whole genome shotgun sequence.
ACCESSION   DAEPXW010000213 DAEPXW010000000
VERSION     DAEPXW010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2647
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.217"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(178..2271)
                     /locus_tag="KRM55_003693"
     CDS             complement(178..2271)
                     /locus_tag="KRM55_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1595877.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVKNPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT          909 a          424 c          252 g         1062 t
ORIGIN      
        1 tatttttatt atggttatcc ctttttaaaa tactttaatc atatactatt cccaatttaa
       61 catccattga aatgctattt tcttatattg caatttataa ttgatatatc ttcaatataa
      121 taatttaatg tatttttgat tttaaagctt ttcagtgata ttattgataa attagaatta
      181 attatctagc tttaaaaggt caaagatttc tgttgctgtc tgcggttttc caaataaata
      241 tccttgtatg taatctggct ttatttgttt aactaaatca tactcttctt gtgtttctac
      301 accttctaaa catactttta ttcctacgtc atgacaaatt gcaacaataa aatgtataaa
      361 tgtagcatca aacttactct ttaatatatc tttaacaaat actctatcaa ttttcactat
      421 atctattgga gaaaatttta aaacttctag agacgagtat cccgtaccaa aatcatccat
      481 agcaatataa attcctaaat cttgtaaagc cttaaattta aactgtaaaa tactcatatt
      541 ttgtactgta tgactttctg tcaattctaa aacaagattt tgataaggaa aattttcatc
      601 atctataatt tttactatat cttcaataaa tgtgtcttct aatatttgaa cagctgaaac
      661 gtttacactc actttaaaaa aaggatagta atcaatccat ttcctaaaag tacgtaatgc
      721 cattcgaagc acccaagccc ctacaatatt tatcatatca ttttcttcta atattggaat
      781 aaattccaaa ggagaaattg ctttgcattt gtcattagtc caccttaaaa gaacttctac
      841 acctattatt ttatgacttt ctgtatctac ttgtggctgg aatcgaagac taaaccccct
      901 aaaatcatca ttaattgatg cctttaaatc ccgcatcatt tctaatgaat acattttatt
      961 ttttaatatt tcttgggaga aaaaaacaag cctgttttta ccatgctctt tcgcatattg
     1021 taaagagtaa ctagcacact tataaagttc ttttactgta tctccatgtt ttggatatat
     1081 tacacaacca gcagaaattg ttatatttaa tccatatttt ctccatagtt gaaggtgtat
     1141 aatcatattc tgtatttgat tatatagagt tagaatttca ttttcttcaa cattatcaac
     1201 aagaatgccc atttcgtccc catcaagttt ataaagttca gcattatctg gtaaaataga
     1261 ttgtatagac tgtgctagtg tttttattat attatctcca aaatccctat catacatctc
     1321 attaacattt ttaaaatcgt caatatctaa taatactatg cataattttt caatcatagg
     1381 atttgaaatt ttatcttcaa atacactcat aaattcatga taattcagta actgtgtcaa
     1441 tgaatcaatc ttattttgtt tacctaattg cgtcattatt cctgcaaaaa tacttggttc
     1501 tccaaattca tcacgcatta gttgacctct acatcttaac catatatatt ctccactacg
     1561 atttttagcc ctaaattcca ctgtatgata atccatctgg tttttaccta tttcagtgtt
     1621 tgacttataa aaacgattcc agtcttctgg atgtacaatt tttttccagt aaacaagcgg
     1681 atttttaaca atttctcctg gtaagtcaaa taattcaact tgtgatggtg aatatcgaaa
     1741 tacgcctgtt ttcatattgc aaatgtatat atattcatct gtacctctaa tcaaagcatc
     1801 gtaaagcaat gtagaattat aatcaaaatt gtctcttgaa aaattaaaaa ctcctttttc
     1861 ttctttatta tttgatattt catgaaattc attaatctta attggtttat ttaagcttgt
     1921 tgagtttgca atatctattg attgatgcat atgaacaact gtgccatctt gccatgtaat
     1981 taaactatca taattttcaa aaacacgatt taacttatta catttttcat accactttat
     2041 taatactcct tttttatcat tctttaataa ttctaaaact ttacaaaaac tacaagtaga
     2101 atttttttca ggatataata cttgccaaca aacttttcct tctggatcta aaatattata
     2161 ttcttctttc atttttttgt tcataaaaat aatttcatta gtatgaatat ttgtaacata
     2221 tatattaatc tgtagttgat ttaatataac ttcaaaatta tgtttgttca tatacttatc
     2281 tcctccatag ttactgctct ttataacaac attgttaaaa ttattctttt tagaagattt
     2341 acttataact tatacatata cactaaatac cttaatttaa ttagaaagtt tattacttca
     2401 tattttaaat tataattgat aaaaaaaaat acagcaatat agtattacca atttaaaaaa
     2461 attaatatta cataatacat ctctctctta tattaaattt taacttggta ctaatcttga
     2521 caaattgtcc acaaaaataa attatatatt ttattattgt tttaaatttt tataaaaaat
     2581 cagtattatt gatactattg aagttaaaaa gcattaattt ctaaaaacat cataattttt
     2641 ctaatag
//
LOCUS       DAEPXW010000214         2611 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.218, whole genome shotgun sequence.
ACCESSION   DAEPXW010000214 DAEPXW010000000
VERSION     DAEPXW010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.218"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            262..2280
                     /locus_tag="KRM55_003694"
     CDS             262..2280
                     /locus_tag="KRM55_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1595878.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
BASE COUNT         1081 a          299 c          430 g          801 t
ORIGIN      
        1 ttgtattaaa tttaataaac ctacaattat tatatgtttt tatttgtctt ttatagattt
       61 ttttggcaat aaatgatata gtgaagataa ttaaatatat tcaatatatt taattttttt
      121 attttttgtt tttataattt ttttagaagt ttatttttta tgtacttatt tataattttg
      181 ggtaaaaaca ctttgatata atttcaaaaa ttaaaaggtt aaaaaacaaa gtagaaattt
      241 atgttaaata aggagattaa tatgagaaga aatacaaaat tattaacaac agggattctt
      301 tcaatggcaa tcgtcgcacc tacaatggca tttgctactg aatctaatgc tatggaaaat
      361 aacgctgatt taaatataaa cttagagaaa aaaagtatcg ttttaggtag caaatcaaaa
      421 gtcagtgtta agtttaaaga aaaaccagat gcagatagca ttacattaaa gtataaatgc
      481 tatgatatgc cattggatac aactctaaat tataatcaat caactgagtc atatgaagga
      541 actatcaatt ataataaaga cccagaatat ttaaatgttt gggaactaca agggataaca
      601 ataaacagca aaaataatcc taaaacttta aacaaacaag aactagaaaa gatgggatta
      661 aatttaaaag actataatgt aacgcaggaa tgtataattg aagatataac ttctagaaaa
      721 gatgtaaata aatatttaag aaaaacttct gcacctatta cagaacttac aggaagtgat
      781 agatacgaaa cagcagttaa aataagtaaa gaaggctgga aaaatggttc agataaggta
      841 gttataataa atggggatgt aagtatagat ggcattatat caactccact agcaactaca
      901 tataatgcgc caatactttt ggttgaaaaa aacaatgtac ctaatagtgt aaaatcagaa
      961 ttaaagcgtt taaatcctag ggatgtaatt ataattggag atgagaatgc tatttctaaa
     1021 actactgcta atcaaattaa atcgactgta aatgctagtc aaacacgtct aaagggctct
     1081 aatagatatg agacatcttt attgatagca aaggaaatag ataaaaatca tgatgtggaa
     1141 aaagtataca taacaaatgc taatggcgga gaagtggatg cacttactat agcagcaaaa
     1201 gcaggtcaag acaagcaacc aattatatta actgataaaa atagtattac agacaataca
     1261 tataaatggt taaagagtga ggatttacaa aatgcttatt ttataggtgg ccctcaaatg
     1321 atatcaacaa atgttataaa taaggtaaat gatataacta aagataatgt tactaataat
     1381 agagtatatg gagcagatag acacgaaaca aatgcaaacg taataaaaaa attctataca
     1441 gatgatgagt tagaggctgt tttagtagct aaatcagatg tacttgttga tgctttagca
     1501 gcaggtccat tggctgccaa cttaaaatct ccaatactta taacaccaaa gacgtatgta
     1561 tctgcatacc ataaagataa tttagaagct aaatcagcta ataaagtata taaaatagga
     1621 ggaggattga cttctaaggt aatgaactct atagcatcat cattatctaa acacaataca
     1681 actccaacag aaccaggaaa tagtgggggt aagacagtta tgattgaccc aggacatggt
     1741 ggttcggaca ctggaacaac aggtaaacca ttagggggta ttaaagaaaa agactataca
     1801 ttaaatactt cacttgcgac aactgaatat ttacgttcaa agggattcaa tgtaataatg
     1861 acaagagata cagataagac tttatctctt ggaaatagaa ctgctttatc taactctttg
     1921 agaccagatt tatttacgag tatacactat aatgcatctg atacaactgg gaatggtgta
     1981 gaagtatttt ataagcttaa agataaagat ggaggaacta ctaagactgt agctacaaat
     2041 atattaaata gaattttaga gaaatttaat ctaaaaaata gaggtgcaaa aacaagaaca
     2101 ctatcaactg accctacaaa agattattta tatgttttaa gaaataatga tatgccagct
     2161 gtacttgtag aatgtgcatt tttggataat gagaaagata tgagtttact taatacatca
     2221 aataaagtaa aagaaatggg tacacaaata ggtaaaggca tagaagattc attaaaatag
     2281 tctacaatga gagcatagaa aaatttaaaa taaattaatc tgcaatttta aatttaaact
     2341 aaagctataa gataagaatg taattataat agtaataaag actgtatata cattgtgcat
     2401 ataagtgcga aatgaggtat atacagtctt tttatgatta attgtaaaag gatttatatt
     2461 atatgaagaa tttacatatc ttaaggctac agttaattgt taagagttgg agtattcatt
     2521 tgtaatacac aatataagct taattactat attttattgt gtgtttgtgt gttttttgtg
     2581 gatttttatg tcaataaatg atatagtata g
//
LOCUS       DAEPXW010000215         2605 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.219, whole genome shotgun sequence.
ACCESSION   DAEPXW010000215 DAEPXW010000000
VERSION     DAEPXW010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2605
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.219"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            212..1102
                     /locus_tag="KRM55_003695"
     CDS             212..1102
                     /locus_tag="KRM55_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH1595879.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINAKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            1320..>2605
                     /locus_tag="KRM55_003696"
     CDS             1320..>2605
                     /locus_tag="KRM55_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH1595880.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
BASE COUNT         1013 a          264 c          458 g          870 t
ORIGIN      
        1 tattatatat tctgataata atccataaaa acatataact ttttagctat aattattatt
       61 gttattaatt gaaaagattt attagttact tgacatagtt tacactttta attatagtat
      121 aaattggaat atttagataa ttattattta atgtataagc taagttttta attaatatgg
      181 ctttatacat ttatatagaa aagaggtacg tatgagtagc acaatcaaat caaatcgaat
      241 aaaaggtata atgtttataa tagcatcagc gcttggcttt gcaatgatgt ctgcattcgt
      301 aaagctagct ggagatttac caagttttca aaaagtgttc tttagaaatc tggtatcagc
      361 tataatagct ttttggctta tcataaaaca taaaggaagt ctaactggta aaaaagaaaa
      421 tttaaaagta cttttatata ggtcaatatt tggaactcta ggagttatat ttaactacta
      481 tgcaattgac aagttgatgc tttcagatgc taatatgcta aataaaatga gtcccttcct
      541 tgtagtaata ttttgtgcaa ttgctctaaa agaaaaaata aatgcaaagc agataggagc
      601 tattataatt gcatttatag gagctttatt cataataaaa ccaacattta gtgtagaagt
      661 aattccatat cttgggggaa ttgcaggagc tgtatttgca gcaatggcat atacttgttt
      721 aagagttctt ggagatagag aagattacta tacaattgta tttttctttt cagttttttc
      781 attagttact gtagggccaa ttgcttttgc agtatatgaa ccaatgaccc ttatgcaact
      841 tatatatcta ttactaggtg gagtatttgc aagtctaggt caatttggaa taactctagc
      901 atataaatat gcacctgcta aggaaatctc tatatttgac tatagtaata taatcttttc
      961 agcaatttta agtatattct tattcaatgt ctatccagat atgttaagtg ttgttggata
     1021 tttaatagta ttttcggcag cattttatat gtttttatac aataagaagt tagataaatt
     1081 agacaaagaa aagaagaagt aaactagata aaagtgtttt tataatttgt attgaatatt
     1141 taagtctttg tattaaaatt aaagaaaatt taattaaaaa tgtttggtat attaacttat
     1201 aacagcagtt aaaattgaaa aattataact gctgtttctt ttattaaaaa tatccaaatg
     1261 tctgtaaaaa tagactataa tagagtagta taaataatat aaaggggata aattaaagta
     1321 tggaaaaagt gaaagttgct gtgattggag caggtaatag aggaacgtat gcatatgctc
     1381 catatattta tgaaaattct gatgtatgtg aaatagttgc tgtagcagaa cctaaaaaag
     1441 gaagacgaga actatttaca caaaaatata acctagatag taaaaatgta tttgaaactt
     1501 tagaagactt ttttaaacat gacaagatgg cagatgcagt aataatagct acaaatgatg
     1561 atagacatta tgatgtagca aaactagctc ttgaaaaagg ttatcatgta ctattagaaa
     1621 agccaatgtc taatagttta gatggtttgg tacatataga tgacttgtgt gataagtata
     1681 aagataagat ttttatgatt tgccatgtac tgagatattc tccattttat aataaattaa
     1741 aagaaattgt agaaagcaaa aaattaggag agctagttag tatacaatat aatgaaaata
     1801 taggatattg gcattttgca catagcttta ctagagggaa ttggagaaat agcaatgaaa
     1861 ccagcccttt aattttagca aagagttgtc atgacatgga tattttgtta tatttagtag
     1921 gaagtagatg caaaaaaata tctgcatttg gaagcttaaa gcatcttaat aaccaaaatg
     1981 ctagtggaga gatggcacaa aattgtcttc agtgtttagt tgaaaaaaaa tgtccatatt
     2041 cagcaaagag aatttattta gaaaaagata gaagtataaa tagagctgtt cacataaatc
     2101 caactgaaga gaatctatta aatatactta agacaagtcc atatggaaga tgtgtttaca
     2161 gatgtgataa taatgttgta gacaatatgg taaatatact acagtttgaa aatggagtga
     2221 cggctacttt taatttatgt gcatttacta aagaaaatgg aagaactata aagttaatgt
     2281 ttagccatgg tgaagttggt ggggatttaa ataaaaatga gataagaatt aaagaatttg
     2341 gaaaaaacga agaaatagtt atgaatccat caaatcaaca gaatatggta gaggaatatg
     2401 atagaaatct tatagctgaa tttattaaat tagtttcaaa taaagaacta gaaaagggta
     2461 gagtagcagc aaaagaagct atacaaagtc atgtaatggc atttgcagca gaatattcta
     2521 gggtcagtga tgaagtagtg tatatagaag aattttttga tagtgctaag caaatgacta
     2581 aggagataga agaaactata tttta
//
LOCUS       DAEPXW010000216         2592 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.220, whole genome shotgun sequence.
ACCESSION   DAEPXW010000216 DAEPXW010000000
VERSION     DAEPXW010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2592
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.220"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..1289
                     /locus_tag="KRM55_003697"
     CDS             <1..1289
                     /locus_tag="KRM55_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH1595881.1"
                     /translation="LIIYISVIRWIFSIHEITLNTENFKRARKESVNLIKGKIIRTII
                     YSLILSLVVAIIGYAIYYSGIIFIGIWTKYCTDMEFLKNVFINRCIAFEEYFRLILSI
                     FIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILLISYIESVAFSSH
                     INGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEIDVQETKDGELIV
                     LHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVGEKIPTLKEMIKY
                     SKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKTILQKVKKLDENL
                     LTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFVWTVNSDSLIEKM
                     LDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            1611..2195
                     /locus_tag="KRM55_003698"
     CDS             1611..2195
                     /locus_tag="KRM55_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH1595882.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         1013 a          242 c          413 g          924 t
ORIGIN      
        1 ttttaataat atatatttcg gttattagat ggatttttag cattcatgag ataactttaa
       61 atacagaaaa ttttaaaaga gcaagaaaag aaagtgttaa tcttataaag ggaaagatta
      121 taagaacaat tatttattca ttaatattat ctttagtagt agctattatt ggatatgcga
      181 tttattatag tggaattata tttataggca tatggactaa atattgtact gatatggaat
      241 ttttgaagaa tgtatttata aatagatgta ttgcatttga agaatatttt agattgattt
      301 tgtcaatatt catttttata ttggacattg gatttatctc agcaacttat tatcaatata
      361 aaggagtaag tatttctaaa aataatatta aaaaagagaa aaaatctata tcaaaaattg
      421 tttttaattt agtattaata ttattaattt cttatataga gtcagttgca ttttcttcac
      481 atataaatgg tatgtttaat acgtcatttt cattttatac aacagcaatt gctcatagag
      541 caggagctga aatggctcca gagaatactt tggcagcaat agaagaagct tcacatgcta
      601 aagctgatta tgcagaaata gatgttcaag aaactaaaga tggagaactt attgtacttc
      661 atgattcaaa ctttaagaga actacaggag tagataaaaa tgtttgggat gtaaattata
      721 atgaagtaaa gacatatgat gcgggaagct tttattatta tggaaaaggt tattatgatg
      781 aaaagtttgt tggggaaaag ataccaacac tcaaagaaat gataaaatat tctaaaggta
      841 aggtgaaatt attaatagaa ataaaactta atggacatga aaagggagac gtagtaaaaa
      901 aagttgttca gttaattaaa gaaaataatt ttgaaaatca atgtatagtt gcatctatgg
      961 ataaaactat attacaaaaa gtaaaaaaac tggatgagaa tttactgaca tgctatttta
     1021 tggcaattgc atatggtgat ttttcaaagt taaattatgt tgatatatat ggaattgaat
     1081 caacttttgt taataaaaca gtagtagaaa agattcataa aatgaacaaa aaaatcttcg
     1141 tttggactgt taatagtgac agtttaattg agaaaatgct tgacctaaat gtagatagta
     1201 ttattacaga taatccatac cttatagaga gtgcaattta ttggaagaaa aatggattta
     1261 ttagtcaagt gtcagattat ttattttaaa tattctataa ttgtattatc cagtaaaaga
     1321 gatattatta aaatcaataa tatctctttt taacataaat aaggttgtta aattaaggtt
     1381 attcttataa aaattgtgct tatcagctat aaacaaggaa taaaagtgaa aaaattgatc
     1441 tgagattatt acagttaaaa gagttttaag atgacagaga gatagattgt caactgtata
     1501 tttaataaat cttgttattt attaaatttt atataagtaa aatatataaa ttaataaatc
     1561 ttatgctaga atatatatga aaaacaatat aaatttggag gattaaaaac atgacagagc
     1621 gagaaaaaat gttggcagga gaactttacg attgtggtga tattgagttg ttaactcaat
     1681 ggcataaagc aaaagaccta gtaagagatt ataaccaaac agattcctcg gatttggaaa
     1741 aaaaagaaaa aatattaaat gagttacttg gtggtaaggg taaaaactta tggattactg
     1801 caccgtatta tgtagattat ggaaataata tttattttgg aaataattgt gaagtcaata
     1861 tgaattgtac gtttttagat gataataaaa ttatcattgg ggataatgca ctaatcgcac
     1921 caaacgtaca aatatatact gcatttcatc caactaatgc tggtgataga tttggtaatg
     1981 ccaaagaaga tggttcattt gaattttgta aaactcaaac agctccagtt actattggag
     2041 ataatgtttg gattggcggg ggtgctatta tcatgccagg tgttactatt ggagataatg
     2101 tagttatagg tgcaggaagt attgttacaa aagatattcc aagtaatatg attgcatacg
     2161 gaaatccatg ccgtattatt cgagaaaata aataaagtta aattttcttg caaaatctca
     2221 aaaaacacct ttcttacttt atacataggg tattttctaa tactttcaca tccatattca
     2281 tttgttaaat ttttgtggaa tgtagttttt atcacttcta tcttacattt ccaccatttt
     2341 ttataaaagt cattccttta tagatttatt tataatagta tatattctat ttgatgtttg
     2401 aataagcact tatttttaag taaaatacta acttttaggt tagtattttg ctatagtatg
     2461 atgattaagt aagaataaaa tactataata cataaagctt aataaatata atttttattt
     2521 tacttagata ttttcttttg attagcaatc aaaagtagtt ataatttttt taattaataa
     2581 gagtaacatt ta
//
LOCUS       DAEPXW010000217         2545 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.221, whole genome shotgun sequence.
ACCESSION   DAEPXW010000217 DAEPXW010000000
VERSION     DAEPXW010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2545
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.221"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(295..1050)
                     /locus_tag="KRM55_003699"
     CDS             complement(295..1050)
                     /locus_tag="KRM55_003699"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH1595883.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDTELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            1490..2479
                     /locus_tag="KRM55_003700"
     CDS             1490..2479
                     /locus_tag="KRM55_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBH1595884.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLIVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
BASE COUNT          941 a          312 c          375 g          917 t
ORIGIN      
        1 gataatattt aataggttta tatgatgaaa agactataaa ataataaaca atatgatttc
       61 atataccaat aaattaggat aatatttaat aggtttatat gatgaaaaga ttataaaata
      121 ataaacaata tgattccata taccaataaa taggataatc tttaagaaaa atgattatat
      181 ttaaaaggta agcataaaat ttataaactt ttagaataga aatctcaatc aattagatat
      241 tcaaattgat gaatatgaat acctaaatag attgagattt attatgtaca aaacttatcc
      301 taatatatct gacattttat aaagcccaga ttgcttacca attaaaaatt tagctgcaac
      361 tatagaaccg tttgcaaata cttcatcaga ttgagaatga tggcttaatg taagaacttc
      421 attatcacct gcaaatataa catcatggtc gctgattata ttgccacctc ttatagagtg
      481 tattccaatt tcatttggtt ttcttttaca atctctacca tatctaccat gtgtattttc
      541 actttcaggc aagacttctc taattgcatt agctatcata gtagcagttc cactaggggc
      601 gtcttctttt ctattgtgat gtttttctat gatttcaata tcaaaacctt ctaacatctt
      661 tgaagcatcc ttaactaatt ttattaatat attcactcca agagatgtat ttgatgataa
      721 taatatagga atgttttttg atgcttcttc tattttattt aagtcatttt catcatatcc
      781 agtagtagct aatactacag gtgtattatt ttttagagca tatgacaata ttggctctaa
      841 agtctcatga tgtgaaaagt ctattattac atcagttttt tcagttacat cagtcattgt
      901 tttgtaaagc tttgtatcac tatgatgacc tttttcatca gcagacctag ctacaccaca
      961 aaccaactct aattcagtat ctttttttac acattctgct aaaactcttc ccattgttcc
     1021 attatagcca ctaattataa ctttcaacat aaattcctcc tatgaaatta ataaaaattt
     1081 gttatatttc tataagttta ttttatcact aatataattt atataaaata atattagtga
     1141 taataagctt acaatttatc ttacattaaa aaatttaagt gaatttttca aaatatagat
     1201 aaatttcttt ttcattgtat aaatgataaa aatatatttg actttatacc aaaaagagtg
     1261 ccccatgaac taaaaagtta attttgaaat accatattca tatatcatat gatttatttg
     1321 gaaatcaata ttaatacatt aaaataacta aatacatgta ttcataaaga tgtataaaaa
     1381 atatataaac atatagtatt aattttaaat tcaacaattt aattgttaaa agtgttatta
     1441 ttaaattaga aatatcttaa cttaatatac tgagatggga gtgatagata tgttaaaaga
     1501 agaaaaaact tatcaagaga aagacgcaaa agtattcaat ggagtggcag ctttgataat
     1561 gattttatta tttttaatag tttcaatagg tatcatggtt tttgggatag taaaacttga
     1621 tagtggattt actggaatag gttcacttat gttaattttg ggacttgtat ttatagtagt
     1681 agattttatc ctattttttg ggctaaaaat gattaatcct aaagaagcta tagttctagt
     1741 tttgtttggt aactattatg gaactataaa aaaagaaggg tactattggg tgaatccatt
     1801 ttgttcagca ataaacccag cagtatcaag aattaatgta tcgaaatctt catctgatga
     1861 aaaggtagat atatcaacta attcaagggg caaaaaagta tctttaaaaa caatgactct
     1921 taataatgaa aagcagaaag tcaatgattt attgggaaat ccaattataa taggagtggt
     1981 tgtaatttgg aaggttatag atgcaacaaa ggcagtattt aatgtggata attataatac
     2041 attcttatct attcagtgtg attctactat tcgtaatgtt tcaagacttt atccatatga
     2101 tgtatctgaa gatggagatg aaaaatctct tcgtggtagt agtcaggaaa tagcagatag
     2161 attaaaagat gaattacaat caagggttga cattgcagga attgaagtgt gtgaagtgag
     2221 aattactcat ctttcttatg caccagagat tgcagcagca atgttacaac gtcaacaagc
     2281 agaggctata atagcagcac gtaaaaagat tgttgagggg gctgtaagta tggtagagat
     2341 ggcattgact aatttaagtg aaaataatgt tgtgactttg gacgaagaac gtaaagcagc
     2401 tatggtaagt aatctgttag ttgtgctttg tggcaataaa gatgcacaac cagtggtaaa
     2461 cagcagttct atttattaaa ttataaaaag tttaatagtt tattttattg atatatagaa
     2521 aatttagtag ttcattttat taaat
//
LOCUS       DAEPXW010000218         2465 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.222, whole genome shotgun sequence.
ACCESSION   DAEPXW010000218 DAEPXW010000000
VERSION     DAEPXW010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2465
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.222"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(73..528)
                     /gene="smpB"
                     /locus_tag="KRM55_003701"
     CDS             complement(73..528)
                     /gene="smpB"
                     /locus_tag="KRM55_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBH1595885.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            1148..1975
                     /locus_tag="KRM55_003702"
     CDS             1148..1975
                     /locus_tag="KRM55_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH1595886.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
BASE COUNT          871 a          320 c          304 g          970 t
ORIGIN      
        1 ttaagaataa aaatcaatgt tatgttctag ataataaaga attttattct aaaaaataca
       61 gttttatcta gtttaatact tacctgtcat ttctctttct atacgtcttt gtgcatcttt
      121 cttagccata tcttgacgtt tatcatatag ttttttacct tttgctaagg caatctctac
      181 tttaacttta ccgtttttta gatacaaact aagtggtata agtgaatacc cctttatagt
      241 agttgctcca ataagttttc ttatttcatg cttatgaagt aataattttc taactcttaa
      301 agaatcaaca ttgaatatat ttccttgctc atatggactt atatgaactt gttttaaaaa
      361 tacttcgcta ttatctacag atgcaaatcc atcacttagg ttaactttgc cttgtcttat
      421 tgattttact tctgttcctt ttaattcaat tccacattca taagtttctt ctataaaata
      481 ttcatgtctt gctcttttgt ttgttgctaa tattttttta ccagccatat aaatctcacc
      541 ttctttgcta gaaatttctt ccataaatgt tagaaattta ctaaatattt aatgttgcca
      601 aattatttga ctaacttgta tgataacata tttaggcatt ttagtcaata tttcactggt
      661 atattaagtt agttaggcta tatataatta agtaatataa atgtatgaaa atagctaaaa
      721 aactacttcg aatatactta atactaaact aactctaacc agtaatacta atttataaat
      781 ttcaaaacaa aaatattaca tattataaat cttctatctt ctatcttcta tcttctatct
      841 tctatcttct atcttctatc ttctatcttc tatcttctat cttctatctt ctatcttcta
      901 tcttctaaat aattttaaca tgcccataaa atataatacc cacaaatgat aaataatact
      961 caaaatgtct attgaaataa ctatacatcc ttaaataact taacttaaat ctaaacattt
     1021 caaaaacttc ttaaaaatat gtaaaaattt gatgataaag tagcgatttt ttcaaaaaaa
     1081 atgtaatata gagttatatc ttataatatt ttagagataa attttatcat agtggggaga
     1141 aatttgtatg gatttaagca aaaaagtaaa aattttagaa aatgcatcag atggcaaaag
     1201 cgaatttgag atattagaat ttgaaaaact tgagggagct tctagcccat taatggcaat
     1261 gggattatat tttgctagag aagctggttt gaaagctaga caaattaaga taaaattaaa
     1321 taattcatca ataaaaacag aagctggtgc attatactat tataaaggaa atatatcttc
     1381 tgaaactaag attggtggtg ttggaggtct ttttaaaaaa ggaatatcag gagcacttac
     1441 taatgaatca atgatgaaac ctgtatacaa aggtactgga gaagtttatt tggaaccttc
     1501 ttttagacat tatttattta tgagtcttga taatgattct ataattgttg ataaaggatt
     1561 attctattgt tgctctgata caatagaagt aaaagcattt acacaaaaga acttctcatc
     1621 tgctttactt ggtggtgaag gcttcttcca aatagaatta agtggtactg gtgtaatcgt
     1681 tctggaatgt gttgtacctc aaagtgaaat tgtagagtat gaattgaaaa atggtgaaga
     1741 attaaaggta gatggtaact ttgcaatagc aagaacatct ggtgttaatt tttctgttac
     1801 aaaatcagat aaatctttaa ttggttctgc tttaaatggt gaaggtttct taaatacatt
     1861 tactggtaat ggtacagttt ggctagctcc aactcaagta atgtatgaaa aactaagttt
     1921 tggagcaatg cctactaatg ataatatgaa taataaagtt tctaagcaaa aatagttgtt
     1981 ttataaatat ttattaaatc attattgatt ttataaagtc actataaatt ttattagatt
     2041 attattataa aatcagagtg tggaaatgtt tatgtgtatt ctttaaataa aaatttccac
     2101 attctgtaaa gttattatac ttgatatata aaattcaatt taggaacata gtctaacatt
     2161 tataaacata ttaaggtaat gatttctctt ggtaattatt ctcatatctt attctttgat
     2221 tatatttatc ttattcctag cccttatgtc atattatatt tcttatctta ttatttataa
     2281 ttagcattaa cttatctaaa atcttgtatt tttttaatag taaagtttac atctatatta
     2341 aaaagtttac atctatatta atttcataaa acaatcaagg tagtcaagag attcaacttt
     2401 atttgatttt aaaaatttaa gtgaatttgt tcttatacac acctttttaa aattatatct
     2461 gtaga
//
LOCUS       DAEPXW010000219         2406 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.223, whole genome shotgun sequence.
ACCESSION   DAEPXW010000219 DAEPXW010000000
VERSION     DAEPXW010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2406
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.223"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            306..1832
                     /locus_tag="KRM55_003703"
     CDS             306..1832
                     /locus_tag="KRM55_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1595887.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKVAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            1860..>2406
                     /locus_tag="KRM55_003704"
     CDS             1860..>2406
                     /locus_tag="KRM55_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595888.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKK"
BASE COUNT          946 a          205 c          439 g          816 t
ORIGIN      
        1 aaaaataata gtaaactgat tgcataaaaa tgatttttat ataaaattta agcagaagaa
       61 taaatttcta acgaaattgg atatttcttc tgtaaataca tattcaaaaa aagaattata
      121 agagtttagt cagcagtcgt gtaagtaata aggtctttat aaatatatag aaatataatg
      181 atattaatat aactaagcga tttttaattt agctttttat taagcttatt ttttatgcta
      241 tttataataa ataaactcca tgatgggaaa actattacta tttaatatgt aaaggagtat
      301 tttaaatgaa tgaatcatat tggtttttaa actcaagtcc aaaagaatat aacaaattag
      361 gtgaaaatat aaaaacagat tgtcttatag taggtggtgg aataactgga ttgacaactg
      421 catatttatt agcaaaagaa ggtaaaaaag tagtgcttgt tgaggctgat aaaataggat
      481 atggaacttc tggaaggaat actggtaagg taacttgtca gcatgatata ttttactcta
      541 agatagagaa aaaatatgga ttagataaag caaaatcata ttataatgca aataatgaag
      601 ctttaaattt agttgaacaa ataatagaag aaaacaatat aaaatgtgat tttaaaaggg
      661 aaacttcttt tgtatttaca gaaaaagagg atactataaa gaatattaaa gatgaatatc
      721 gtacatgtaa aaaaatagga ataaattgtg agtatcatga aactatagaa aatattccat
      781 tagatataaa gggggctatt agttttacta atcaaggtca atttaaccca aagaagtata
      841 ttgatggatt ggcaaaagta gcagtaaatt tagggctaaa aatatatgaa aatacaccag
      901 tagtagacct tgaaaaagga aaaatatgta gggttaaaac aagagaagat aatataatag
      961 aagctgagaa tgttataatt tcatctcata gtccatggta tgatggattg aatttttatt
     1021 ttgcaaaaga atatgcagag cgtgcttatt taatggttgc agttttggaa aataaattag
     1081 cagatggtat gtttataagt atagatgacc catcaataac ttttagacaa tataatgatg
     1141 gaagtgaaaa tttactgatt tttggaggag gagaccataa agttggtcag ggaggaactg
     1201 agaaagaaat atttgatgat ttagagcatt atggtaaaga agtctttaag gtaaaagatt
     1261 ttaaggggaa atggtctgct caagataata tgagttttga caatgttcct tatattggtt
     1321 atatcaacaa aagagaagac aatatttatg tagctacagg gttctctaaa tggggaatta
     1381 ctaatggaac tgctgctgga ataataataa aagatttaat aataaataat aattctgatt
     1441 ataaagatac ttttaatcca tccagactag gtagctactt ttcaaaagat tttataaagg
     1501 aaaatgcaaa cgtagcaata aattatgtaa gtggaaaatt aaaaataggt agtggagata
     1561 tgcctaaaaa taatggagaa ggaaagattg ttaatattga tggaaaaaga tatggtgtat
     1621 ataaggatga taatggagat ttttatattg tagacactac atgtactcat ttaggatgtg
     1681 aacttaattt taacagtgaa gaaaaaacat gggactgtcc atgtcatggt tctagatttg
     1741 actataaggg aaatatactt gaaggaccag ctcttaagcc attaaaactt tatggacatg
     1801 gtgataatga tgttaatcct aagttattat aaaattattt ttaggaaggt aaagtgtata
     1861 tgaataaact tttaaagcca ataactatac tattgtatat agtttatatt ttatctgccg
     1921 tattttttgt agcaaacaaa gaatatggaa gtctaggtct agtagcaatt agtttagttg
     1981 gtactttcat tttgagtttt ataaataagc aaactgaaag attattgagt aaagaattat
     2041 atataatgct tgctttattt ataatgtttt catcattgtt aggtacttgt tttaattttt
     2101 atgatataaa ttattatgat gattttttgc atttatggtc aggtataata tcttgtattg
     2161 tggctttttc tataattaaa tacttttata cacaaagaga gataagtaaa atgagtaaag
     2221 tgtttttagt tatattttta tttatgttta gtatgggagt agcgagttta tgggaaatag
     2281 gtgaattttt aatggatact tttgttggga ctactacaca ggccggaggg ttagaagata
     2341 ctatgattga tatggtagat gctttaatag gcacaattat aactattcct tttatagtaa
     2401 aaaaat
//
LOCUS       DAEPXW010000220         2397 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.224, whole genome shotgun sequence.
ACCESSION   DAEPXW010000220 DAEPXW010000000
VERSION     DAEPXW010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.224"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(104..2086)
                     /locus_tag="KRM55_003705"
     CDS             complement(104..2086)
                     /locus_tag="KRM55_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNRLRE domain-containing protein"
                     /protein_id="HBH1595889.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECPPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGEIGPTGVTGPTGNTGATGSIGPTGVTGPTGNTGVTGSIGPTGVTGPTGNTGVTGS
                     IGPTGATGPTGNTGEIGPTGATGPTGVTGSIGPTGVTGPTGVTGPTGVTGSIGPTGVT
                     GATGVTGEIGPTGATGPTGATGPTGPTGVTGSIGPTGATGPTGNTGVTGEIGPTGVTG
                     PTGATGPTGNTGEIGPTGVTGPTGATGSIGPTGVTGPTGATGVTGEIGPTGATGPTGP
                     TGVTGSIGPMGVTGPTGEIGPTGATGPTGNTGATGSIGPTGVTGPTGATGSIGPTGPT
                     GATGNSSQPVANFLVNAPSPQTLNNGDAITGWQTIIGNSSSITVDANGTFTVQENGVY
                     YISVSVALQPGSSSINQYSFAILFPILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGTT
                     FTINNFSSTTVGIRNGQSAGTAATLTIFRIADTVMT"
BASE COUNT          555 a          533 c          370 g          939 t
ORIGIN      
        1 ttgttatttt attcattcta aaataggtaa aactcaatat ataaaaatac ttttgtcatt
       61 taaataaagc ctaaatagtt tttaagatta ttttagacac gttttaagtc ataacagtat
      121 cagctattct aaatatcgtc aaagtagccg cagttcctgc tgattgccca tttcgtatcc
      181 ctactgttgt agatgaaaaa ttatttattg taaaagtagt cccaccaaat aaaaaaccag
      241 caaaatatcc agaaagtact cctccgcctc ctggctcagt agtaagccct gccaaatctt
      301 ttcctcctaa aattgggaat aggatagcga aagaatattg atttatactt gatgaacctg
      361 gttgtaatgc tactgaaact gatatataat acacaccatt ttcttgtact gtaaacgtac
      421 catttgcatc tactgttata cttgaactat ttcctattat tgtttgccaa cctgttatag
      481 catctccatt atttagtgtt tgtggagatg gtgcatttac gaggaagtta gcaactggct
      541 gagaggaatt acctgttgct cctgttggtc ccgttggtcc tatacttcct gtcgctcctg
      601 ttggacctgt tactcccgtt ggccctatac ttcctgtcgc tcctgtattt cctgttggtc
      661 ctgttgctcc cgttggtcct atttctcctg ttgggcctgt tactcccatt ggtcctatac
      721 ttcctgtcac tcctgttggg cctgttggtc ctgttgctcc tgttggtcct atttctcctg
      781 tcactcctgt cgctcctgtt gggcctgtta ctcccgttgg tcctatactt cctgttgctc
      841 ctgttgggcc tgttactcct gttggcccta tttctcctgt atttcctgtt gggcctgttg
      901 ctcccgttgg gcctgttact cccgttgggc ctatttctcc tgtcactcct gtatttcctg
      961 tcggtcctgt tgctcccgtt ggccctatac ttcctgtcac tcctgttggg cctgttggac
     1021 ctgttgctcc cgttgggcct gttgctcctg ttggccctat ttctcctgtc actcctgtcg
     1081 ctcctgttac tcccgttggt cctatacttc ctgtcactcc tgttgggcct gttactcctg
     1141 ttggacctgt tactcctgtt gggcctatac ttcctgtcac tcctgttgga cctgttgctc
     1201 ccgttggtcc tatttctcct gtatttcctg ttggacctgt tgctcctgtt ggtcctatac
     1261 ttcctgtcac tcccgtattt cctgtcggac ctgttactcc tgttggtcct atacttcctg
     1321 tcactcccgt atttcctgtc ggacctgtta ctcctgttgg tcctatactt cctgtcgctc
     1381 ctgtatttcc tgttggtcct gttactcctg ttggccctat ttctcctgtc gctcctgtac
     1441 ttccggttgg gcctgttact cccgttggtc ctgtacttcc tgtcgctcct cttggtccca
     1501 ttggacctgt aattctaatt ggaggacact cacatttagg ataacaatta tctataattc
     1561 tatcttcaaa tgttacaagt atatacggtt tgttacaacc tctactagat gtaaattcaa
     1621 gaatctgata agggtaattt aaagataaag ctaacccata attaggatat ttattcattg
     1681 cccatgcttt tatagttccc gtaatattta aacaaatata gttggatgta tcacttatcc
     1741 caattggtaa atatcccctg atattttcca tagacactct atcattccat gttatagttc
     1801 gtaaattata atattcactt attcttttaa tttcaatatc tactttttct ttaaaaatat
     1861 gattcttatt tgaatcaata tgaataaata actctgcttt taatatactt ttgtctttta
     1921 atatatctgg tattctcact ttaaaaaaag taatcaactt ttcttttaca aaactatttg
     1981 aacatttact tcctattaag caataatcta aattactaaa gtttttatct ggatattttt
     2041 tagatataaa agtatcatca tttaaataaa gtataatatt tctcatttat aatccctcca
     2101 ttttgggtct atatcatact atgtttaaaa tgcatgctta gttacaatac aattaaaatt
     2161 tatagtatta aatttttata taataatgct gatttctaca aaaaaagaac atgtcattag
     2221 aaatttctaa tagcatgttc tttttcatta ttatatatta cactttaaat tattccttga
     2281 ctggcttagc tggtgtaaac taaaccagtc tttctaaaat attaagcact tttttcttat
     2341 tatgtttttt aggatttatt gtctatatta ttgtaaacca aagttataaa attgtaa
//
LOCUS       DAEPXW010000221         2376 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.225, whole genome shotgun sequence.
ACCESSION   DAEPXW010000221 DAEPXW010000000
VERSION     DAEPXW010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2376
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.225"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            24..497
                     /locus_tag="KRM55_003706"
     CDS             24..497
                     /locus_tag="KRM55_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595890.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFKDTAVEQIVDGIRFTPMKLLI"
     gene            complement(866..1423)
                     /locus_tag="KRM55_003707"
     CDS             complement(866..1423)
                     /locus_tag="KRM55_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595891.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSFL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            1681..>2376
                     /locus_tag="KRM55_003708"
     CDS             1681..>2376
                     /locus_tag="KRM55_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1595892.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIVENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT          869 a          319 c          300 g          888 t
ORIGIN      
        1 taataataaa ggtgttgttt ataatgttca aggaatactt aataagagaa ttaaaagaag
       61 atgatattaa aaatgcatta gacttaatct ggaacgtatt tgaagaattt gaatctccag
      121 attattgtga tgaaggaatt acgacatttc atcaatttat agaatataac tctattattg
      181 aaaaaatcaa agaaaaaact ctcttctttt ggggttgttt tgactctaaa aaacttattg
      241 gagtcttagc tattagaaat ttaaatcata tatgtatgtt atttgtagat aaaaactatc
      301 ataaacatgg tgttgcaaaa aaattaatga ctacaggcat acaatactgt atttgtaata
      361 aatttaattt aactgaaata actgtaaatt catcacctta tgctgttgaa gtttatcata
      421 aattaggatt taaagatact gctgttgagc aaattgttga cggtatacgt tttacaccta
      481 tgaaattgtt aatataataa attaaataaa aagcaaagtc tcttaaatat tttatagtta
      541 ctttgctttt aaaccaagat ttaaaataat actatctttt ttgtttttta ataatatact
      601 ttaaaagcct tactaatatg aactataatt tattttttga tatccttttt gattaacata
      661 taaattaatt caattattaa acataaacta tgttgtttct ctttatatct cttctttgta
      721 aacaatattg ggcatttgaa aataaatatt cttaaaatat actgttctcc tgttgatttt
      781 cctttggtac aaatgataaa aatttaattt atatgcccca taatgaagtg ttcaataaat
      841 aagttaaaat aatttattta cctccttaat catatttttt atgaatacct aataacacag
      901 tatcaataga atcgactaaa ccttttatag cttcttcttt actcaaaaat gatttcccaa
      961 gttgcaaagt cgaataacca tgaagtacac tcattattaa gtttaatact tcacctgtat
     1021 tctttgtatt tagattacaa gaaagaataa gtttttctaa taaggattta tattcatcaa
     1081 agatttctaa tgtttcatta tttccatgcc aagtagccca ctgaattgtt tcataaacac
     1141 caggattaga aattataaaa ttaaagtatg ctatacttat acactttata gctgtatctc
     1201 caaaatttcc aatagccgcc tttatcattt gactattcat ctctctcatt cctttatgag
     1261 ctacttcaag taataaatca tctagacttt ctatatgatt gtacaaagat ggtgtacgta
     1321 ttcctagctt ttctgcaata acttttaaag aaactttgtt aagcccatct ttattaacta
     1381 tatctgatgt agcttgtata actatttctc tactaacacg catgattttc cctctttcat
     1441 ttaaaattaa ttactttatt agtttagcta atctaattag tttcgtcaat tattgtaatt
     1501 tataaaattc tttatactat tataaaatct tgacagttta attataattt aatataatac
     1561 taattgaatt agttttaata ctaattcaat tagtattata ttaaattata tattacaaca
     1621 ttattttata gtttgattaa tttaacaatc actaatatat caaactgaaa ggagattttt
     1681 atggaaaaaa aatatttcga aattcatgga gttccttcaa tcctttgggg aaatccttca
     1741 agtaaattat atatttacat acatggacaa tgtggcaata aagaggaggc tgaagctttt
     1801 gctaatattg cagttccaca tgagtgtcaa gttttaagtg ttgatttgcc tgaacatgga
     1861 gaacgtaaaa gagaaaaaaa ttcatttaac ccatggcatg ttgttccaga attagtatct
     1921 attatggaat atgcaaagtg ccactggaat caaatttcgt tatatgcaaa tagcattgga
     1981 gcatggttta gtatgttaag ctttgaaaaa gagaacttaa gagagtgtat ttttgtatct
     2041 ccaattctag atatgcaaca gctcatttca aatatgatgc tttgggcaaa tgtatcagaa
     2101 gaacagctta aacatgaact aattatccca acttcatttg ggcatactct ttcatgggaa
     2161 tatctacaat atgtaaaaca acatcctatc actcaatgga atgtaccaac aaaaatatta
     2221 tatggtaaac atgatgaact tactgaaatc ggtgttgtag agaaatttgt agaaaagttt
     2281 aattgcaacc ttactattgt agaaaatggc aaacattggt ttaacacacc acaagaatta
     2341 aattcattat atgaatggtt aaatacttta gttaaa
//
LOCUS       DAEPXW010000222         2360 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.226, whole genome shotgun sequence.
ACCESSION   DAEPXW010000222 DAEPXW010000000
VERSION     DAEPXW010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2360
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.226"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            201..1652
                     /locus_tag="KRM55_003709"
     CDS             201..1652
                     /locus_tag="KRM55_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH1595893.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1872..2333)
                     /locus_tag="KRM55_003710"
     CDS             complement(1872..2333)
                     /locus_tag="KRM55_003710"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBH1595894.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAVICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
BASE COUNT          811 a          271 c          402 g          876 t
ORIGIN      
        1 tatattataa aaacaataaa aaaaggtttg atttgaatat aaaactgcaa tatattaaaa
       61 aaattattca ttttaaacct tgtaatttga ttttataaat attataatta aattaatgaa
      121 tttttaacaa ggaattattc atttttttga ttttaagatt tattgagaaa acaaaactaa
      181 ataggggggt aattaatata atggattttt tcaatggtat tttaacgagt attaacaatg
      241 cagtagtatt tgtaaacaat tacttatggt cgtatatctt aattataatg ttagttgtaa
      301 ttggtattta ctttactatt aaaacaaatt ttgtacaatt cagatatttt atagaaatgt
      361 ttagacttct gggtgatggt acagcgaata aaaatgcaaa aaaggaagga aaaatctctt
      421 catttcaagc attttgtata agtacatctt caagagttgg aactggaaat atagctggaa
      481 tagcaattgc agtggtagca ggaggacctg gtgctgtatt ttggatgtgg cttatagcat
      541 taattggttc tgcatcaagc tttgttgaga gtacattagc tcagatttac aaagtgaaag
      601 atggtcaagc ttttagaggt ggaccagcgt attatatgga acaaggtcta aataaaaaat
      661 ggatgggtat tttattctca atacttataa ctatatgtta tggttttgta tttaatgcag
      721 ttcaagcaaa tactgtttca cttgcattta ataatgcatt tggaataagt aaaatggcta
      781 tgggaatagg tcttggaatt ttaactgcaa tagttatttt tggtggagtg catagagttg
      841 caaaagtttc tgaaataata gttcctgtat ttgcaggatt atatatatta gttgctttgg
      901 ctatagttgt aatgaatata acagagatac caagtgttat agcattgata gttgaaagtg
      961 catttgattt taaaggaatg gcgattggta catttatggg agttgtaatg actggagtga
     1021 agagaggtct attttctaat gaagcaggta tgggtagtgc tcctaatgct gctgcaacag
     1081 cacatgtaac tcatcctgta aaacaaggtt taattcaatc tttaggtgtt tttacagata
     1141 ctataataat atgtagttgt acagcattca tggtattatt atattcaggt tatagtagta
     1201 gtggagcaac tggaattgaa ttagctcaag aagctttaac tcatcatata ggaccagttg
     1261 gaaatatatt tatagcagtt tgtatattct tgtttgcatt tagttctata gttggtaatt
     1321 actattatgg tgaatcaaat atggagttta tgagtggaag taagactaaa cttaatgtat
     1381 ttagagtttt tgttgtaggt atggttttat ttggttcact tactcaagta gatgtagttt
     1441 ggaatcttgc agacttattt atggcattga tggcgataat aaacttaata gcaatagcac
     1501 ttttaggaaa atatgcattt attgctttaa aagattatac aagtcaaaaa aaatcaggaa
     1561 taaaagaccc tgtgtttatt gcagatgaaa tagaaggcct agaaaaggta tcagagtggc
     1621 atagggaatt atctgaggaa catttaggat aaaaaatagt ataaaattat aaaaccattt
     1681 tgaaagacta gagtatgtat atactttata tgaatataat attgaattaa tttatattac
     1741 tggaattttt aattccagta atattttttt attatataat ttagctttat taaaagtttt
     1801 tattattaaa aatagcttat ttatcgtaaa gtgaatgata ttgggttttt aattattatg
     1861 aatgttagta tttaatttaa agacttaaat aaatttgcca tttctagcgc attcatagca
     1921 caatcataac ctttatttcc agcttttgta cctgctcttt caatagcttg ttcaatattt
     1981 tctgtagtta cgattccaaa tataacaggt aattcactgt ctaaagatac tttggctatc
     2041 cctttagaga cttcactaca tacataatca taatgagaag tagcccctct tataacacag
     2101 cctaaacaga ttacagcatc atacttacca cttttagcca ttttttgagc aacaagagga
     2161 atctcaaaag ctccaggtac ccaaactatt tctatatttt ctggagaaac gtcatgtctt
     2221 aaaagacagt cttcagctcc tgataaaagt tttgatgtta taaattcatt aaaacgagaa
     2281 tttattatac ctatttttaa atcttttcca ataagttttc cttcatatat catttttatt
     2341 tcctccaatt ttatttatgt
//
LOCUS       DAEPXW010000223         2281 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.227, whole genome shotgun sequence.
ACCESSION   DAEPXW010000223 DAEPXW010000000
VERSION     DAEPXW010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2281
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.227"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            133..1014
                     /locus_tag="KRM55_003711"
     CDS             133..1014
                     /locus_tag="KRM55_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH1595895.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(1075..>2281)
                     /locus_tag="KRM55_003712"
     CDS             complement(1075..>2281)
                     /locus_tag="KRM55_003712"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBH1595896.1"
                     /translation="KSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGLD
                     PSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVLA
                     NAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRYE
                     GQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIMM
                     PLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVNK
                     IESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQV
                     KEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGKK
                     KFVKIELVK"
BASE COUNT          762 a          384 c          302 g          833 t
ORIGIN      
        1 tgcaaataat gtcatataag ttacacttta gttatcttag ttacaacttt gtcggtttac
       61 tttttctact ttcttcgata taattataat atatttttga tacaattcga caaaaggggg
      121 aatgctgtaa ttatggtaaa aaaaagaaaa aagaaaactg ttacacttac tatacttgtt
      181 gtaatagtta ttggtatttt ttctatggca tgggcggaca tgtctagaaa aaaagaaatg
      241 aaagaaactc aagaaagact taaagctgaa agattagaaa aagaaagaat tgaaaaagaa
      301 aaaaatgaac ctattattgg tgcaaaaaaa gaagctgtaa aagaatatgg atatgacgca
      361 aaaatagttt gggacaaact taacaaatac gactattcaa acaatggaga aaagatagtc
      421 tttcttacat ttgatgatgg accatctact actaatactc cacaagttct agatatcttg
      481 aaaagacatg gtgttagagg aactttcttt attaagggtg attctcttga aagaaaagga
      541 gctaatgaaa ttttaaaaag aacatttgac gaaggaaatg caatagccca tcactcttat
      601 actcatgact ataaaaaact atatcctaac agaagcctaa atctcgatac attcgtaaat
      661 gaacttaaca aaactgatga agctatgaaa aaagtcttag gaaagaattt ttcctcaaat
      721 gtagttagat gcccaggcgg gtatatgtca tggaaaaata tggaacctct aggaaactac
      781 ttaaaagaga aaaatatggc atcaattgat tggaacgctt taaatgctga tgcagaaggt
      841 aaaaagaaaa atgcacaaga attatttgaa catgcaaaga aatcttctga aggcaaagaa
      901 atggttgttc ttttaatgca tgatacttat ggaaaacaag aaacagtaaa tgcattggac
      961 caaattataa catattttaa agacaatggt tatcaattta aaattttaat ataataaaaa
     1021 agcaagttta ttgaatgtac attttatact caatagactt gcttttactt tactctattt
     1081 tactagctcg atttttacaa attttttctt tcctatttga acaactaatt cactctcttt
     1141 tacaatagtg cttaaatcct ctactttttc accatttacc tttactccac cttgagaagc
     1201 taatcttcta acttcactct tactcttaac aatctcatta gaaactagta cttcgattaa
     1261 gtcaaatcca tcttccttaa cttgaattgt ttgtatatct tcaggtattt gacctttttg
     1321 gaatacagat ttaaatcttt cttcagcttc tttagcagat tcttctccat ggtataatgt
     1381 tactatttct cttgctaagt tcatctttat atctcttgga tttactgaac cctctttcaa
     1441 ctgtgattct attttattaa cttcatcagg atgaacatct gtcactaaat tgtagtattt
     1501 aattataagt tcatcaggaa tttccataga tttttggtac attattcccg cttcttcatc
     1561 tattccaata tagttaccta aactcttact cattttttct ttaccatcta atccttctat
     1621 taaaggcatc attattacta tttgagactc cataccaaat tctctttgta atgatcttcc
     1681 cattagtaaa ttgaatcttt ggtcagttcc accaagttct atatcagctt ctaatgctat
     1741 agagtcatat gcttgcatta atgggtagaa gaactcatgt actgatattg gcatttgtcc
     1801 ttcatatctc tttttaaaat cttctctttc taacattctc gcaacagtaa tagttgctgc
     1861 taattttatt acatcttcaa aatttaactt agctaaccac tcgctattaa atcttacaat
     1921 agttttttct ttatctaaaa ctttgaaaat ttgttcttca taagtttttg catttgcaag
     1981 aacttgctct gttgttaaag cttttctagc tttagatttt ccagttgggt ctccaatttt
     2041 tcctgtaaaa tctccaatta ttattactat ttgatgacct aaatcttgta attgtttcat
     2101 ctttctaaga actactgtat gccctaaatg tatatctgga gcacttgggt ctagacccaa
     2161 ttttactatc ataggctttc cttctttttc tgatttaata agcttttccc ttaactcttt
     2221 ctcatctatt aaatcatcta cacctttcat aattattcgc atttgctcgt ctatcgattt
     2281 c
//
LOCUS       DAEPXW010000224         2273 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.228, whole genome shotgun sequence.
ACCESSION   DAEPXW010000224 DAEPXW010000000
VERSION     DAEPXW010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.228"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(138..1430)
                     /gene="brnQ"
                     /locus_tag="KRM55_003713"
     CDS             complement(138..1430)
                     /gene="brnQ"
                     /locus_tag="KRM55_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH1595897.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGIK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          761 a          373 c          247 g          892 t
ORIGIN      
        1 aaataaattt ttaaatttat caaataggat taataatgtt cttttatcta caataattta
       61 ataattcttt taaatataaa aaggaattgc ctatataatt taaaggcaat tccataatta
      121 tcaattagtt tttattatta tgcagtttta ctgcttttag atggaataaa gtttcctatt
      181 attcctgcta ttacaactgg aactatccag ttaaatccta atgaagcaaa tggtaagcta
      241 ttaactagag gaatttttat accaaaactt gttgcaactg ttaatacact tactaataat
      301 gccatgtatg cagcacattt gaacacgttg tcatttttaa ttttattact aaataatgct
      361 agtataacta gagttatagt tgctggatat accatactta gtataggaga agagaattgt
      421 attattgtac ttactccaaa gtttgatatg attgcactaa atacacaaac tactataact
      481 atatgctcat actttaattt tccatctgta agtgttgaga aatattgacc agctgctgaa
      541 gaaagaccta tagctgttgt taaacatgct aatgcaacta taatagccaa taaaatttta
      601 cctgtagttc caagtaaagc tgctgttatt gcaactatta aagctgtttg ttgaacatct
      661 tgtccatatt gttgagacac agttgctcca agataacata atccaccata aactaatgcc
      721 attcctatta ctgcaattac acctgcactt attgtggctt tcatcttttc tttctcacct
      781 gtataacctt tagctattac tgacatgatt ataattgatg caaatacact agctgccaat
      841 gcatccattg tttgataacc ttgagttata ccttctgcaa atacattttg tattaaagaa
      901 ctgtctctta tttctcctaa tggagatacg atacctttaa ctattaatac tgccaaagct
      961 ataagtaaag ctggagttaa tattgaccca actatatcta caacttttga tggtcttatt
     1021 gttaaaacca atactagagc aaagaatact atagagaata ttactgggct tattccagaa
     1081 cctattgtag gtaatatacc catttcataa gttgttgctg ctgttctagg tattgctaaa
     1141 agtggcccta tacagattac cattgcacat cctaatgcaa tacttaatcc tttgcctgct
     1201 cttgagaaca tcttcgatgt gtctccattg aacttagttg ctgctataac tgctaataat
     1261 gccaaaccac catctgcaaa aaggaatcct atgaaagcta ctagccaact acttccagat
     1321 aaaactccta gatatggagg gaagattaag ttccctgcac caaaaaacat tgcaaatagt
     1381 gcaaatccaa ttacaattac atctttaaaa ttgatttgtt tctcacccat ttaaagcacc
     1441 cccatttgaa ttttactacc ttttactaaa aaataagtcc aatctcttaa ttaaatgaaa
     1501 accttttgac gagattttat ttaattatac atttttgact taaatttgtc aattatgttt
     1561 cataatttat aaaatcttca caatatttaa tacaactttc ttaattaaac aaaatcaacc
     1621 tgtatacttt aaacatagtt ggttttttgt tttttctcta atttttcttg ataaaattaa
     1681 ctattccgaa taattaaaat attaagactt tttagattat tcgatttatt attaagttgt
     1741 attgctttat atactgtata tatcactctc cttttttaca ttcatataat ctttttaatt
     1801 caatttaaat tttaaatatt ttgtgtttat tatataatct gaaaaaaaag cagtcaatag
     1861 catttttaat ttttttaatt ttcaaaatta tgattcttaa aaaatcgttt tccttttatc
     1921 ataacaccta tttacgttaa ttcttgtagt attttgtatt tattttgcta aattgacagt
     1981 taactttatt caatttttat tctacttacg tagatttgcc tcttgttttt tactcttaaa
     2041 accatttttt ctgaaaattc cttattatga tttatcaact tatttttctt cataacaatt
     2101 actctctaac ttccaactta cttaaacttt gcagttgcta gtattcacgt ttacatactt
     2161 atatgtcata attaactaaa aattcttaat atatctctca atgaaaacaa tttactcatt
     2221 tatttaatac atttatataa tcatatgtct taaattttgt tttattattt tat
//
LOCUS       DAEPXW010000225         2150 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.229, whole genome shotgun sequence.
ACCESSION   DAEPXW010000225 DAEPXW010000000
VERSION     DAEPXW010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2150
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.229"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(49..1266)
                     /locus_tag="KRM55_003714"
     CDS             complement(49..1266)
                     /locus_tag="KRM55_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBH1595898.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTTDLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(1457..1870)
                     /locus_tag="KRM55_003715"
     CDS             complement(1457..1870)
                     /locus_tag="KRM55_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1595899.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
BASE COUNT          750 a          334 c          239 g          827 t
ORIGIN      
        1 aagtgatttt ttagattata tattttaata tactttctta tataagaatt attttaaatc
       61 aagattatct agtattttta aaaatatttt tacagcagta tccaagtcat ctacagagac
      121 actttcatta ggattatgac ttacgccccc agcgcatctt ataaatacca taccaatatc
      181 agttatatta tccatttcct gagcatcatg gccagcacca ctataaatat aaaaaggatt
      241 aagatttaaa tctataaaac ttttttctat gatttttgtt attttattag aacatggtac
      301 aggaacattt tcaaaagcaa gttcacttgt ataattaagt tttctatttt cacatatatg
      361 tgatatttca ttaaatatct tttctacaga attatcaaga atttcttgtg aacaagagcg
      421 tacatcgagt gtaaattcag ctctttcagg taccacattt gatgaagatg gatagaaatt
      481 catctttcct acagtagcaa ccaaatcagt agtcgtttta gctacttttt cgatagctaa
      541 tacacattca caggcacaac atccagcatc aagtctcata ttcattggaa gtgtaccagc
      601 atgtccagac ttaccattta ctgatatctt aaaactttta aatcctgtaa tacttgatac
      661 aattccagca ggaagagatt cattttctaa aacaggaccc tgctcaatat gaaattctaa
      721 atatgcatct acatcttttc taggatgcaa atttgttaag ttttttgtat taaatccaaa
      781 ctttgttaca gcttcttcaa gtgtaattcc attttcatca acagatttaa gaagttcctc
      841 tttaaaagta ccagcaaaaa ctttacttcc cattaaagaa gtttcaaatc tagttccttc
      901 ctcttcagcg aaagcaatta gcttaatatt gaaaggataa gacctattat tgtgttttgc
      961 ttcttcaaga ccaactagag gcactattat acctaacata ccatcaaata tacctccaca
     1021 ctttacacta tcttgatgag atgcaactac taatgtggga gcatttggaa agcttgattt
     1081 atatgtacct ataacgtttc caatgtcatc aatttcaata tcaagattta aaccttccat
     1141 ccatgaacta attaaatcaa tagatttttt atgttcttga gtcaagataa gtcttgtaag
     1201 accatttgtt gttgaactta tttttcctaa tgtttgtaga taatccatac atttttttcc
     1261 taacatattt acctcctaaa aatataattt ttatttaagc taagattagc ttttatactt
     1321 ataatttttg aactttcaaa taattttgta tgtatagtaa aatactattt tagtattaat
     1381 aatgatataa aaacataaag tctgtagacg aagagcagaa gttttaattt aaaaatatga
     1441 aatatgattt ttattattat agtatttttc tataataata tctctttcca gttagaggat
     1501 aattttcaag tgaaaatact ttatggtatc caaatttctc ataaaattta ggtgcttgaa
     1561 aactgaatgt atctaaaaaa acatatttac aacctcgttc tttagcaatt ttttcagcct
     1621 tatataaaag ttgacttcca gtacctttat atctaagctt ctcactaacc cataagtatt
     1681 ttatagaaag ccaattacca tgagtaacac ctataaaacc tgcaacaatt ttacctgctt
     1741 tatctcgaat atatattcct aaatccactg ggtttttatc ttcaagtcta gcaagattat
     1801 attttaataa tccttgaaaa atagtatctt catcttgttt ttctattttt tctgtaattt
     1861 ctaattccat atttgaactt tctccttgta taatcttttg tatattggta ttttttaata
     1921 aaatcagtag aaagaatata gtttaacatt attctaatag gcatttatgc taatgtcaaa
     1981 ctaataatac ttattcttaa ttttatattg ttgatattaa atttttttaa ataaaaatgt
     2041 agtttaagtt atataaaaag aaatcatcaa taaatttagt aaacctaaat tgttgaatat
     2101 taaaataagt taatttaata caaaaaaact attttagatg ttattctatt
//
LOCUS       DAEPXW010000226         1932 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.230, whole genome shotgun sequence.
ACCESSION   DAEPXW010000226 DAEPXW010000000
VERSION     DAEPXW010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1932
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.230"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            44..442
                     /locus_tag="KRM55_003716"
     CDS             44..442
                     /locus_tag="KRM55_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595900.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    878..1141
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1292..1843
                     /locus_tag="KRM55_003717"
     CDS             1292..1843
                     /locus_tag="KRM55_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBH1595901.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          815 a          186 c          292 g          639 t
ORIGIN      
        1 atattataat gaactagtta aaaattttta tgagggggaa aatatgaata agaagaaaaa
       61 attgattggg atagctatat cttttctact tataatcagc attataaatc cattacaagt
      121 agaagcagaa gctattattg agtctagtgt atacatttct tcaataaaag agaattatac
      181 atatgataat actaaattta aaactattaa atctaaaagt agacataaaa gtaggaaata
      241 taataaaagt aaagtaaagt tgaaaaaacg aagtataaga actaaaaagt atggatatca
      301 aactataaat aaatataaaa gacaaaacgc aagaagacat aatatcctaa caaaattaat
      361 attgtccata atagtcatat ttttggttat agttttagta gtgctaatat ttattaaaag
      421 aaagaagaaa aaattttact aaaaataatt aaaagaatat cattttttta atcattggta
      481 tctatttaat aatatgatgt aattaaaatg gagtaatatt ctgtttcaaa ggaggcatat
      541 aaatacagga atgagtatta aatgatggtt aattaagtaa atttattgat aaatgtactt
      601 aattaacttt gaagaattta attcctcatg aatcaaaata taaaattaca tcaacagtta
      661 ttcacaaaat taatataaga agaattagag ccaaagagca gactattaga ccattaaagt
      721 aattattcat agaattttgt atatgaaaag aaatgtatag tataatttac tttttttata
      781 aaaaatagat tacaaaatat attttttata aaaaggtatt gacatttttt agaaaaaaga
      841 atatcattat tttaacaaca aaattcaata caataaatta aatcctatga caaggaagag
      901 tagttaaatt taggttcagt atagagagct gaggatggtg gaatcttagc aagaaaaaat
      961 ttgatgaatg gcccttagag gaataaattg aaatcatagt tttgagagta gactttatcg
     1021 tcagtcgcac gttatagcga ataaggtatg taagtacctg ataatgagat gtatgaaaat
     1081 tgaattttat attaattttt atataattta ggtggcaacg cggataatct ccgtcctatt
     1141 agtttaggac ggagtttttt attttactga aaatttaaaa gatagaaggt ggtgagaaag
     1201 atgttatgaa tttcaaaagc taaagatgat gatatagtag gttggcaaaa aaataaattg
     1261 aaaattaaaa aaataggagg aagtacaaaa aatgaaaaca aatacaaaaa aattaacttt
     1321 aaatgcaata cttttagcga tgggattatt aatacatcaa atcacaccag ctataggatt
     1381 accaatgaag ccagatgtac cactagcaat gttatttgta atattggttt taaatagaga
     1441 tgattataaa acttgtttga tagcgggtat agtaacagga atatttacag cacttacatc
     1501 aagttttccg ggaggtcaaa ttcctaatgt aatagataaa actcttacag caaatatagt
     1561 atttttatta atgaatatta gttataatat gccttttata aaaaaattag ctaagaaaac
     1621 acaagatact gtagtagttg caataataat gccaatagga actcttgtaa gtggaactat
     1681 ctttttatta gcagctcaag ctatagttgg tcttccaggg gcttcattta cagctttatt
     1741 cttagcagta gtattaccag ctgttttaat aaatctagtt gcaggaatat ttttattcaa
     1801 gattgttagt ctatcaataa gaagagttag ttatcaagct taaacacgaa ataatatttt
     1861 actttataaa gcattataat aactaaataa cataagaata aagtagatta taactatttt
     1921 attcttatgt tg
//
LOCUS       DAEPXW010000227         1904 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.231, whole genome shotgun sequence.
ACCESSION   DAEPXW010000227 DAEPXW010000000
VERSION     DAEPXW010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1904
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.231"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            276..956
                     /locus_tag="KRM55_003718"
     CDS             276..956
                     /locus_tag="KRM55_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595902.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKIRNITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
     gene            1404..1688
                     /locus_tag="KRM55_003719"
     CDS             1404..1688
                     /locus_tag="KRM55_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595903.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
BASE COUNT          833 a          123 c          280 g          668 t
ORIGIN      
        1 tatataattg tatatgctta tctttataca gtaaataaaa aatcaaatga aataccaaat
       61 aaagtgtata tcttaaaata acttactaga gatacaagga tgctatgtga attttgaagt
      121 gtgcagttta gataataaat atatataaat aataaagaaa atggatttat agtatttaaa
      181 atttcttata agggtaaaaa atgctattag aaaatgtact aaaaatattt ttccaattct
      241 ttatagaaaa ataatgatat ttagaagaga ttgtaatgca aattgatgta ttgataattg
      301 atggagataa gaatagttct caagagctga aaaatttttt agaaggaaag gggataaatg
      361 tctatttagc atataattgt aaagatgcta ttataaaaat atttagcaag aaatttgact
      421 taatattttt agagataatt ttagttgatg gtgatggttg ggatttttgt aaaaaaatta
      481 gaaatataac tacttgccca attattcata taacttatat aaatgaaaat caaagtattt
      541 taaatgcttt aaattctgga ggagatgatt atttaataaa gcctttaaat ttagaaatat
      601 tatatgcgaa agttaaagct attttaagaa gaagagattt atttttaaat aataataaaa
      661 ataatataaa actagaagat tataatagag ctagtggagt aataaagtta gaaaataaaa
      721 tgataaagtt aactccaaca gaaaatagat tattaaatta ctttatagag aatgctgaaa
      781 agactctaac tattaaggag atatatgaac atgtatggat gaatgagtat ttagatgata
      841 attatagtgt agtggttgct gtgagtggat taagaaagaa aatagagaaa gattataaaa
      901 atcctcaaaa aattataacg ataagagaag tagggtatta ctttaacaag atataaagct
      961 ttataaacag aatgaatgat aaggcataga taatatgtta gtatattata agagtttttg
     1021 ttctaacgat atatttgtaa aattagattt aatttactta attaaattat agcagtagaa
     1081 taaatataaa aaatgtctga aatattatag acatcagtaa aatatataaa actataatat
     1141 aagtcgtaat aataaaacaa atgaatatta attaataaaa agatagtagc tatttttata
     1201 tagctattat ttttttattg ttgtggatga aaatatactt atattttact aatatacatt
     1261 taaaaattat aatttaaagc attaaaaaat aaatttgtat tttgttttat ataaagtaat
     1321 ttgaagaata tggaaaaact tgattagtac attattaatt agggtataaa atggtgtaaa
     1381 tagaatgata aggggtggat gaaatgcttg tatataataa aagtttttat cctaatgaca
     1441 tatttccaag attagatttt tcaaaaataa aaaaacagtt aaaattgata gataatgacc
     1501 tgtcagattt tggaagcata tgtataatag aaaaagaaca ttatacaata agtgtaaaca
     1561 gtataggtga aataaatgtg tattatgatt tagagtacga aaataaggtg tatagaatag
     1621 tttatgagat tgaaaagtta tttaaatctc aagttggaag gtttagcata tctacataca
     1681 gaaattgata attaaaaaag tagaaattaa aaaacttaat actaaagata tagataaata
     1741 tatgaggtaa cagctagaga gagttgttac cctttttaaa tactaagtat atattattct
     1801 tattaatttt ttgtaaattc actaaaagac ctttttatag aatattattt tcttttttta
     1861 ttaaataggt aaatcagtaa aaatgcaatt ccagttccaa ttat
//
LOCUS       DAEPXW010000228         1891 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.232, whole genome shotgun sequence.
ACCESSION   DAEPXW010000228 DAEPXW010000000
VERSION     DAEPXW010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1891
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.232"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            85..201
                     /gene="rrf"
                     /locus_tag="KRM55_003720"
     rRNA            85..201
                     /gene="rrf"
                     /locus_tag="KRM55_003720"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            208..282
                     /locus_tag="KRM55_003721"
     tRNA            208..282
                     /locus_tag="KRM55_003721"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:240..242,aa:Asn,seq:gtt)
     gene            287..361
                     /locus_tag="KRM55_003722"
     tRNA            287..361
                     /locus_tag="KRM55_003722"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:320..322,aa:Glu,seq:ttc)
     gene            367..442
                     /locus_tag="KRM55_003723"
     tRNA            367..442
                     /locus_tag="KRM55_003723"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Val,seq:tac)
     gene            448..524
                     /locus_tag="KRM55_003724"
     tRNA            448..524
                     /locus_tag="KRM55_003724"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:482..484,aa:Asp,seq:gtc)
     gene            535..609
                     /locus_tag="KRM55_003725"
     tRNA            535..609
                     /locus_tag="KRM55_003725"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:567..569,aa:Thr,seq:tgt)
     gene            624..708
                     /locus_tag="KRM55_003726"
     tRNA            624..708
                     /locus_tag="KRM55_003726"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:658..660,aa:Tyr,seq:gta)
     gene            718..791
                     /locus_tag="KRM55_003727"
     tRNA            718..791
                     /locus_tag="KRM55_003727"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:750..752,aa:Gly,seq:tcc)
     gene            802..878
                     /locus_tag="KRM55_003728"
     tRNA            802..878
                     /locus_tag="KRM55_003728"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:836..838,aa:Arg,seq:tct)
     gene            888..963
                     /locus_tag="KRM55_003729"
     tRNA            888..963
                     /locus_tag="KRM55_003729"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Gln,seq:ttg)
     gene            975..1050
                     /locus_tag="KRM55_003730"
     tRNA            975..1050
                     /locus_tag="KRM55_003730"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1008..1010,aa:Lys,seq:ttt)
     gene            1053..1141
                     /locus_tag="KRM55_003731"
     tRNA            1053..1141
                     /locus_tag="KRM55_003731"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1087..1089,aa:Ser,seq:tga)
     gene            1159..1249
                     /locus_tag="KRM55_003732"
     tRNA            1159..1249
                     /locus_tag="KRM55_003732"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1193..1195,aa:Ser,seq:gct)
     gene            1258..1334
                     /locus_tag="KRM55_003733"
     tRNA            1258..1334
                     /locus_tag="KRM55_003733"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1292..1294,aa:Pro,seq:tgg)
     gene            1420..1495
                     /locus_tag="KRM55_003734"
     tRNA            1420..1495
                     /locus_tag="KRM55_003734"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1453..1455,aa:Trp,seq:cca)
     gene            1556..1632
                     /locus_tag="KRM55_003735"
     tRNA            1556..1632
                     /locus_tag="KRM55_003735"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Pro,seq:tgg)
     gene            1639..1715
                     /locus_tag="KRM55_003736"
     tRNA            1639..1715
                     /locus_tag="KRM55_003736"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1673..1675,aa:Ile,seq:gat)
     gene            1719..1794
                     /locus_tag="KRM55_003737"
     tRNA            1719..1794
                     /locus_tag="KRM55_003737"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1752..1754,aa:Phe,seq:gaa)
     gene            1802..1878
                     /locus_tag="KRM55_003738"
     tRNA            1802..1878
                     /locus_tag="KRM55_003738"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1836..1838,aa:Met,seq:cat)
BASE COUNT          475 a          440 c          516 g          460 t
ORIGIN      
        1 taactctaaa aaaaaataaa aaaagtattg acaaaaatag taaaaaatgt taatattata
       61 cttgtcctag caacaagaaa aaaatgtggt tataatagcg gagaagatac acctgtttcc
      121 attccgaaca cagaagttaa gttctctagc gctgatggta cttggtggga aactacctgg
      181 gagagtagga catagccacg tgaatgttcc aaggtagctc aacggtggag caaccggctg
      241 ttaaccggta ggctgtgggt tcgagcccca cccttggagc cattatggct cgttggtcaa
      301 gaggttaaga caccgccctt tcacggcggt aacaggggtt caattcccct acgagtcacc
      361 atttgtggga tcatagctca gctgggagag cacctgcctt acaagcaggg ggtcacaggt
      421 tcgagccctg ttggtcccac catttgcggc ctggtagttc agttggttag aatgccagcc
      481 tgtcacgctg gaggtcgagg gttcgagccc cttccaggtc gccaaaataa aaatgctggt
      541 gtggctcaac ggtagagcag ctgacttgta atcagcaggt tgtaggttcg attcctatca
      601 ccagctccat gtaaaactaa tacggaggat ttcccgagcg gccaaagggg gcagactgta
      661 aatctgttgt catcgacttc ggtggttcga atccaccatc ctccaccaat taaatatgcg
      721 ggtgtagctc aatggtagag ttctggcctt ccaagccagc tgtgagggtt cgatcccctt
      781 cacccgctcc aaagaaagcg tgggtgcata gctcagctgg atagagcaac gcccttctaa
      841 ggcgtgtgtc cggggttcga atccctgtgc gctcaccaca tatatattgg ggattagcca
      901 agtcggtaag gcacatgact ttgactcatg tatgcgtagg ttcgagtcct gcatccccag
      961 ccaaataaaa atatggtcta ttagctcagt cggtagagca cctgactttt aatcagggtg
     1021 tcccgcgttc gagtcgcgga tagatcacca atggagaggt gtccgagtgg tttaaggagc
     1081 tggtcttgaa aaccagtgac ttcgaaaggg gccgtgggtt cgaatcccac cctctccgcc
     1141 aaaaaaatga ctgaatttgg agaagtactc aagtggctca agaggatccc ctgctaaggg
     1201 attaggctgg gtaaccggtg cgagggttcg aatccctcct tctccgccat tcaaaaacga
     1261 ggtgtagcgc agtttggtag cgcacatggt ttgggaccat ggggccgggg gttcgagtcc
     1321 cttcacctcg accaacttaa gcttttagtt cagttggtta gagtgcccaa ctcatggcta
     1381 gtaattctag ggtttgagtc catgaaggtt attcttcata ggggtgtagc tcagttggta
     1441 gagcgtcggt ctccaaaacc gtgcgccggg ggttcgagtc cctccacccc tgccaaataa
     1501 aaaggacttg aaaaaagttg gattttagag tagtataaga tagtaaataa gatttcgagg
     1561 tgtagcgcag tttggtagcg cacatggttt gggaccatgg ggccgggggt tcgagtccct
     1621 tcacctcgac caagaaaagg gcctatagct caggtggtta gagcgcacgc ctgataagcg
     1681 tgaggtcgct ggttcgagtc cagctaggcc caccatttgc ccagatagct cagtcggtag
     1741 agcaggggac tgaaaatccc cgtgtcggtg gttcgattcc gcctctgggc accaggaata
     1801 cggcggtata gcttagttgg ctagagcgtt cggttcatac ccgaaaggtc ataggttcga
     1861 ctcctattac cgctaccatc taactatatc a
//
LOCUS       DAEPXW010000229         1856 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.233, whole genome shotgun sequence.
ACCESSION   DAEPXW010000229 DAEPXW010000000
VERSION     DAEPXW010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1856
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.233"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            206..1546
                     /locus_tag="KRM55_003739"
     CDS             206..1546
                     /locus_tag="KRM55_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1595904.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSRMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT          752 a          127 c          294 g          683 t
ORIGIN      
        1 aaatttatat agttattatt aaaaaaagca ataaaaagtt taattcaatt tagcaaattt
       61 agtgatataa ttaaaaaaga aaagaaatat ggacttattt ggaataattt tgacaatcta
      121 tttactacac gtgtagagtc gtatataatt aaattataca taaaatataa aaaaataatt
      181 tagtaatacg ttaggagaaa gtattatgat aaagtcaagc ttattttgga atattttcat
      241 tgcgatatcc tttatgatag aatggtttct ttgtaagaaa atgctagatt atacaagtga
      301 gaaaaggatt tctaacaaaa aaataaactt ttgtatggta ggtattattg tttttgctga
      361 cataatatat ttttttgatg tacctccaaa tataagagta attatatcca tgataattac
      421 tattgcattt tataaaatct catatgatgt ggggtttata aagtctgtat taatatcctt
      481 aatttattgg atgttactaa tcgccacaga tgctttgagt atatctttaa cagtttggct
      541 taattctata aatgacatga gtcgtatggg gacgggagat atatacagaa ttgagtctat
      601 aatattggga aagatacttt tgattgtgtc tttgctttta tatagagcct taaagataaa
      661 acttaatata gaaataaata aaaggacatt attttatata gttattccta tagtcgctaa
      721 tatagcatct ttttttgtaa tttttgaata catatttaat ccagggtctg gtagcttaat
      781 acataatttc caattcgtta tgatttctgt tgtattgctt atatcaagta tcactttagt
      841 tttaattgct aaaaaattac agcaatataa tactttagtt gtagaaaaca atatgattaa
      901 aaatactttg aagtatgaaa atgagtatta tgaagatata gaaaagaaat atttaaaaac
      961 tagattacta agtcatgata tgaaaaatca catattgtgt ataaatgcta tgattaaaaa
     1021 aggtattgat gttacttctt atttaaataa tttgcaggta gaaattcaga gtaatgactt
     1081 gttatttaat actggtaatt ttatattaga tgctatatta agtgaaaaga aagaggtttg
     1141 tgataagaat gatatagaat taaaaatagg aataaatttt agttgttgtg aagctgttga
     1201 attagtagat atatgtcata tattttcaaa tattttagac aatgcaattg aggcatgtaa
     1261 taaaattgat agtggaaata gagttatttg tgttaaaggt gatgttatgc aaaattttta
     1321 tttaataaga gttgaaaata ctaagatgaa taagattatt actaaaaatg gagatatttt
     1381 gacagacaaa aaaggttctc ttcatggact tggaataaaa agtgtaaaaa actctgtaaa
     1441 taagtatggt ggtaatgttg taattgaata tgatgataaa aaatttgtag ttaaaattgc
     1501 tattccactt agaaatgtga agaaagcagt taatcatgtg atttaaatgt atataaattt
     1561 gatgtgtaga aatttaatat ataagaatta atgtataaaa gtgatgcata gaagtttaat
     1621 atataagaat taatgtataa aattgatgta tagaagttta atatataaga attaatgtat
     1681 aaaagtgatg tatagaagtt taatatataa gaattaatgt ataaaagtga tgcataaaag
     1741 tttaatatat aagaatttaa taagtataaa agtttaatat ataggaattt aataagtata
     1801 aaagtgatgc ataaaagttt aatatatagg aatttaataa gtataaaagt gatgca
//
LOCUS       DAEPXW010000230         1826 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.234, whole genome shotgun sequence.
ACCESSION   DAEPXW010000230 DAEPXW010000000
VERSION     DAEPXW010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1826
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.234"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            170..1219
                     /locus_tag="KRM55_003740"
     CDS             170..1219
                     /locus_tag="KRM55_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1595905.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            complement(1369..1716)
                     /locus_tag="KRM55_003741"
     CDS             complement(1369..1716)
                     /locus_tag="KRM55_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1595906.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
BASE COUNT          680 a          248 c          279 g          619 t
ORIGIN      
        1 tcaatataat ttatccagta ttacacatta ctaaaaaaac taaacataaa actgaaaatt
       61 attattaagt ttttgtagaa atattataag catagataca tttttgtaac aactacaata
      121 aatttttaat actatatact attcgtatgt cttatgggag gtatttatta tgtttaaaaa
      181 aatagtcgca atagcaagct ctatcattgt aagtacaata tgtctaactg gatgtgattt
      241 taactctaat gacaaaaaag atgaatcttc ttcgtctaaa aatctggata aagtaactat
      301 agcagaagtt actcactctg ttttttatgc tccacagtat gctgctatta cgaaaggatt
      361 ctttgaagat gaaggtataa agattgacct tataaatacc caaggtgcag ataaaactat
      421 ggcagctttg atttcaggtg aagcaaacgt aggtttaatg ggtcctgaag catctatata
      481 tgtatataat caaaacaaaa acgattatgc agtgaacttt gctcaattga caaaaagaga
      541 tggtagtttt ctagttgcta ggaaaaaaat gcctaatttc tcttacaatg atttaaaagg
      601 aacagaaata ttaggtggta gaaaaggtgg agttccacta atgacttttg aatatgtttt
      661 aaaagaaaaa ggtcttacta ttggagaaaa tctaaaagca ggcaatgtta atgtaagaac
      721 tgatgtacaa tttggtgtaa tggctggagc ttttgcaggt ggagagggtg actttacaac
      781 agcatttgaa cctacagcaa cagcaatgga aaaagaaggt agtggatata tagttacatc
      841 tataggaaaa gattctggag aaataccttt tacagcatac tctactacga gatcatacat
      901 gaaaaacaat aaagatttaa ttcaaagatt tacaaatgct gtttataaag gtcaattatg
      961 gattcaacaa gcatctagca aagaagtagc taaggctatg caacctttct ttgaagatat
     1021 atctttagaa gatttaacaa cagttgtaga tagatataaa tcaatagatg catggtctca
     1081 aaatcctgta ttaaaagagg aaggtttgaa gaaattgatg actgttatga aagaagctaa
     1141 agaactagat aaggaagcac cttataaaga tatcgtaaat actgagtttg caaacaatgc
     1201 tataaaaaat attaaataaa atatattagt tttagctaga tattttcttg tttttataat
     1261 gaaaattaac aaaaatataa aaagagcctt ttaaaagact ctttttatat ttgagattaa
     1321 agtttatata ataaaataga tattaaagta ctaactgtac ttatatatct atcctctgta
     1381 ttctgctcca gcattaattt ttgtaatttg aacggctacc atttcttcat tgcttccatt
     1441 agtaatttca tgccactctc ctgttggtac aaatacagta tcgccgtttt ttacatcaca
     1501 ttcatgctca ccaagtttca ttttaccttc tccttttagg aacacaaata tttgttcacc
     1561 attagggtgt ctatgagcat taagaacttg attaggttta aaataataaa cttctgaagt
     1621 tatatcatta ccagcaaata ctggtatttt tggaactgct gtatcattat attgagctaa
     1681 acttccgtct aatagattct ttttattttc atgcatacta gaaatacctc ttttctatat
     1741 tatagattta ctattattat accaatataa gaaaatagta ttctcacttt acacaatagg
     1801 aataaaattc ttttattttt aaatat
//
LOCUS       DAEPXW010000231         1764 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.235, whole genome shotgun sequence.
ACCESSION   DAEPXW010000231 DAEPXW010000000
VERSION     DAEPXW010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1764
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.235"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            116..1714
                     /locus_tag="KRM55_003742"
     CDS             116..1714
                     /locus_tag="KRM55_003742"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBH1595907.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
BASE COUNT          673 a          218 c          274 g          599 t
ORIGIN      
        1 tttatataat attttttcac taaatttttt tctttttaca acaaatactc actacctttt
       61 gatataatat ttttatcaat tattattata ttcaagtttt gaaaggagta ttaaaatgag
      121 tttattagtt ttcggacata aaaatccaga tacagattca atatgttctg caatttcatt
      181 agcacattta aagaacaaac taggaataaa agcaacagct tatgctttag gagatatcag
      241 aaaagaagct aaatatgcct tggattactt taaggtagat gcacctgaaa ttttagataa
      301 tgttagaata caagttagag atttaaatta tgataaagta gtacctttaa caccaacttc
      361 atctatatta gaggcttata accttatgga tgaaaaaaat gttaaaacac tacctgtaac
      421 ttatgatgat ggaacttttg ctggtatcat tactatgaaa gaaatagcta aaaatctact
      481 tcatcaacac tttacaacta tacacacatc actatcaaac atttgtaaaa accttaatgg
      541 tactattctt gtggactgtg gtgaagatat aaaaggtaga gtagtcactt tatcatttgg
      601 aatggagact ctaatagaga ctttaaaaga aggagacata gctattgttg gagatagata
      661 tgatagtatt gaatatgcta ttgatacaaa agttaaactt ttaatactta ctaatcatac
      721 agagatttca aaagatttgc tagctcttgc taagataaat ggagtgtctg ttgtttctgt
      781 tgaaagtgac aattataaaa cttctaatgt aataaatcaa tgtagtttct tagactctat
      841 agaagctaca gaaaatttaa ttacattcaa agaagatgat tatatggatg aaataaaaga
      901 gattatgcta gaaacaaact tcagatctta tccaatatta gatgatgata ataagttttt
      961 aggtttagtt tcaaaaggtc atctattaaa cccatctaaa aagaatgttg ttttagttga
     1021 ccataacgaa tatgctcaaa gtgctgatgg aattgaacaa gcaaacatag ttgaaataat
     1081 tgaccatcat aaacttggtg gtatttctac tgatgttcct atgtcattta gagttatgcc
     1141 tgttggatgc aatagtacta taatttatca aatgtacaaa gaaaataatg ttgagatacc
     1201 ttatgaaata gctgggcttc ttttatctgc tatattatca gatacattat tatttaagtc
     1261 tccaacaaca actgatatgg ataagaaagc ttgtgaagaa ttaagtaaaa tagcaaaagt
     1321 agacatggaa aaatacgcta tggatatgtt taaatgcggt acttctttag atgaatatac
     1381 tatagaagaa atagtaaata tggactttaa agaatttaat atgagtggac atagagttgg
     1441 tattgggcaa gtatttacct tagacataga ctctatattt gctaaaaaag atgagttttt
     1501 atcttatata aattcgactg attatgataa attaattctt tcagttacag atataatcaa
     1561 agaaggttct tatttaatct ataaagcaga agatagctta attgctaacg catttggtgt
     1621 tgaaggtgtt caaggcacat ttgcaccagg tgttgtatca agaaaaaaac aattagtccc
     1681 taatttaact actgcaatca aaaattttaa ataatataaa atttttaaat aacgaaaact
     1741 gtctcaaatc tatatttgag acag
//
LOCUS       DAEPXW010000232         1711 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.236, whole genome shotgun sequence.
ACCESSION   DAEPXW010000232 DAEPXW010000000
VERSION     DAEPXW010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1711
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.236"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            80..814
                     /locus_tag="KRM55_003743"
     CDS             80..814
                     /locus_tag="KRM55_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1595908.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(957..1448)
                     /locus_tag="KRM55_003744"
     CDS             complement(957..1448)
                     /locus_tag="KRM55_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH1595909.1"
                     /translation="MNNQQQEVYKKLDELNIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
BASE COUNT          644 a          199 c          247 g          621 t
ORIGIN      
        1 atataaaagt gataaaaact tatattttgt atttaataga gtgttgctaa gtgaatatat
       61 ttaaaatgga ggaaacttta tgaaacaaaa taaatatgat gatgatagat tttttaataa
      121 atacagtaaa atggaacgtt ctacaaatgg attagcaggt gctggagagt ggcatgtttt
      181 aaaaaaaatg ttacctgatt tcaaaggaaa aagagtttta gatttaggat gtggatttgg
      241 atggcattgt caatatgcag ttgagaatgg agcaatttct gctgttggag ttgatatttc
      301 agaaaaaatg ttaaaagaag ctagaaacaa aacgcaactt gataatataa attacatatg
      361 tatgcctatt gaagatatta attttccaaa agatagtttt gatgtagtta ttagttcctt
      421 ggcatttcat tatattcaat catttgaaga tatatgtaag aatataagta attgtctttc
      481 aaataaaggt aattttgtat tttctgttga acatcctata tttactgcat atggaagtca
      541 agagtggtac tgtgataaag atggaaataa tctacactgg ccagtagata gatattttga
      601 agaaggagta cgtaagtcaa attttctagg agaagaggtt ataaaatatc ataaaacatt
      661 aacaacttat ttaaatacgt taatgaaaac aggatttgaa atattagaaa ttattgaacc
      721 tcaaccagaa gaaaaactgt tagatacaat tcctgatatg aaagatgagc tacgtagacc
      781 tatgatgtta cttgtatctg caaaaaaaag ataagtaaat ataaataatc attattgtag
      841 aaaaaaagtt gtagaaaata attatactaa tggagatgat tataccagtg gtattaatta
      901 caccagtagt aaggaggcaa aagcattcgt tgcttttgcc attttttaag ttgcaattat
      961 acttctacgt agtatatttc gtttccattt tcttctataa gctttttcat atcttcaaat
     1021 tttaaaaata cagtagcagt attatcattt ggatgtatac ctattttatc catttttaat
     1081 aaatccttat caaatacaac ttttacaaca gcctctttat catttaatat accaaaagga
     1141 gtcacagctc ctttagtaag tttcaagtat ttttgaagtc tttcttctga tgcaaaacta
     1201 agaggtttac tatcaatttg ttgacgaata tcttttaaat ctgctttttt gtctttacct
     1261 aatacaacta aaaaatgttc ttttccttta gcatcacgaa gaaataggtt ttttacaaca
     1321 aattccatat gtaatgtttt taattcttcc atttcttcaa ttgtataaac tggtggatga
     1381 tttacagcct cataaggtat gtttaactca tctaattttt tatatacttc ctgttgttga
     1441 ttgttcatga tttcctccca ttagaaattt attttatata taaataatat tatcacagaa
     1501 aactttaaaa gaaaacgttt tatataatat agacaataga ttatattttt ataaagaagc
     1561 aagaatactc aataaaactt aaagaaatta aacaatttct aaaaatacct tgaaaataga
     1621 accttatttg ccatttataa attatataaa aagggattat ataaagtcat atatgaaaaa
     1681 actatattat actatctttt ctttttggaa t
//
LOCUS       DAEPXW010000233         1685 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.237, whole genome shotgun sequence.
ACCESSION   DAEPXW010000233 DAEPXW010000000
VERSION     DAEPXW010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.237"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            173..1609
                     /locus_tag="KRM55_003745"
     CDS             173..1609
                     /locus_tag="KRM55_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBH1595910.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT          688 a          169 c          280 g          548 t
ORIGIN      
        1 atttttaata taaatgtaaa tacaattata gctaaatgaa taattgtatt aatatttatt
       61 tgtaatatgc ttaatataat ttgcaatttt acataagttt gttaagtaca taactaattt
      121 aagaatatgt atttatatat taaaaattta ttatgagggg gacaatttta ttatgaaatt
      181 ctataaaaga atattaacat tgactttaag tatttctttt gtatttgcaa atattcaatt
      241 agtagatgca atatcatctg tagaaaaaat acaaggaaaa aataagtatg aaatcgcagg
      301 taaaatagca gataaaaatg catataaaac tgctatatta attaatacta gtaactctat
      361 tgcagatgga ttaagtgcaa gtggactagc aggagcttta aatgccccta tactattaac
      421 tgaaaaaaat actataccaa ctgagacatc tgcaagatta aaaaatgtat caaaagttta
      481 tataattgga ggaacatatt ctattagtac atctgtcgaa aattcattaa aatctaagaa
      541 aatgaaagtt gtaagaatta agggaaatga cagaataaaa acaagttata atgttgcaaa
      601 agaaataaat tcaataaaaa aagtcaatac tgttatgcta accaatgcat ataaaggaga
      661 agcagatgct ataagtattg catctgtagc agcaagagat aaagcaccaa taattcttac
      721 taatggacaa agtatacctt tttcaactag tggtttaaag tcttatgtaa taggaggaac
      781 agcttcaatg agtaccactt tagtaaacaa tactaaatct actagactag gggggagtac
      841 tcgttttgaa actaataaag caataataaa taagttttat aaggatgcta gagagtttta
      901 tatagctgga gcttatgaat taacaaatgc acttgtagga tcttctttat caaaacatgg
      961 tccaatggtt ttagttaatg atggtagcaa taaaagcatt ttaaaaaatg ctaagaagat
     1021 aacttctata ggatatatag attcaaatat agtacaacag tgtttaaata taacaaatgg
     1081 aattggagat attaatactg gggttgtaaa aaatgttaaa cctactacaa agactataaa
     1141 agatggaatg tataaggttg gaaaagatat ctcagcaggt gaatacttaa taacttcaaa
     1201 ctcaggaagt tatgcttctt attatgaagt tacaagtgat agtacaggta atgctgatag
     1261 tatactttca aatgatattt ttagtgggac tagatatatc accttaaaga atggtcaata
     1321 tattaaaatt gaggattcaa caatgacatt agcaaagtat gctaaagccc agaaggccaa
     1381 gaatggtaag tttggaaatg gtatgtataa aattggatta gaaattcctg ctggagaata
     1441 tattataatg tcaaattctt ctgatgcata ttatgaagtt agaaatgata gcttaggtaa
     1501 tgcagaggga atagttacta atgatacttt ttcaggaaga agatatataa cggttgagga
     1561 aggtcaatat ttaatattaa atgattgtta tttaattgaa aatgaataga tgtaattgta
     1621 tttaatagta aatcatatat tttatttaag gaaaggtgtt ttaagtttta atttaaaaca
     1681 tcttt
//
LOCUS       DAEPXW010000234         1675 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.238, whole genome shotgun sequence.
ACCESSION   DAEPXW010000234 DAEPXW010000000
VERSION     DAEPXW010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.238"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            305..1576
                     /gene="serS"
                     /locus_tag="KRM55_003746"
     CDS             305..1576
                     /gene="serS"
                     /locus_tag="KRM55_003746"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH1595911.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRAYMGVSVIK"
BASE COUNT          714 a          169 c          297 g          495 t
ORIGIN      
        1 aaatttatat aaaagttaat aactatacaa gattgataaa gaaaaagtca aaatagataa
       61 ttgattagca aaatagatat aattataatg aagttaaatc tagcaatatt ctcctaaaat
      121 taaatttcat ttatttaatt aaatataatt tgacaatgga caaaaaagtg agtaaaatat
      181 aaataaaata aaaataacag gttcggataa agaaaaaggt ttcttaacct caagcataaa
      241 gtatattatc taagttattt gagattaaga gataaatcca atcttaagta ctgaggagga
      301 aaaaatgctt gatataaaaa gaataagaga aaatttagat tgtataaaaa aagcaatgga
      361 aagaaggggc gaaaaagact ttaaccttga tgaagtagtt aagttagatg atgaaagaag
      421 aaagattctt caagaagttg aagttatgaa aaatgaatta aatacagcat ctaaaaatat
      481 accaaatctt ataaaagaag gtaaagatgt agaaaatgaa aagattaaac taaaagagtt
      541 atctgataaa attaaggtaa tagaccaaaa tcttaaagaa gtagaagata agatggaata
      601 cctattaatg agaataccaa atgtaccaca tccagaagta ccacaaggtg aaactgatga
      661 agataatgtt gaagtaagaa cttggggaaa gactactacc tttgattttg aatctaaggc
      721 tcattgggaa attggaacag aattaggtat acttgatttt gaaacagcta gtaaaataac
      781 tggttcaaga tttactcttt acaaaggatt aggtgctaga ttagagagag cattattaaa
      841 tttttactta gacacgaata caaaagtaaa tggatataca gaagttattc caccatttat
      901 ggcaaataga aatagttttt taggtacagg acagttacct aagtttgaag aagatatgtt
      961 taaaatagaa ggtatggact attttatgat tccaacatca gaagttcctt taactaatat
     1021 acatgctaat gaaatactta aatttgaaca attaccaata aattatacag cttatactcc
     1081 atgttttagg tcagaagctg gttctgctgg aagagataca agaggtttag taagacagca
     1141 tcagtttaac aaagtagaaa tggttaaaat agttgcacca gaagaatctt acaatgagtt
     1201 agaaaagctt actaacaatg cggaaactat gctacaatta ttgaatctgc cttatagagt
     1261 agtaaagata tgtacaggtg atttaggatt tacggcttct tttaaatatg atgtagaagt
     1321 ttggatgcca agttacaata ggtatgttga gatttcatct tgttcaaact gcgaagattt
     1381 ccaagctaga agagcaggaa taagatttaa aagagataaa gattctaaag ctgaatatgt
     1441 acacacatta aatggctctg ggttagctat tggaagaagt gttgcagcta tattagaaaa
     1501 ttatcaacaa gaagatggtt ctgtggttgt tcctgaagtt ttaagagcat atatgggagt
     1561 ttctgttatt aaataagagt taaattatgt atttttaagc aatacaataa tatagaggta
     1621 ataaaaaata attaatataa aagtgatact tctaatatag aagtaataaa aaaat
//
LOCUS       DAEPXW010000235         1665 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.239, whole genome shotgun sequence.
ACCESSION   DAEPXW010000235 DAEPXW010000000
VERSION     DAEPXW010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1665
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.239"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            68..1306
                     /locus_tag="KRM55_003747"
     CDS             68..1306
                     /locus_tag="KRM55_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH1595912.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYLSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDKNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT          705 a          143 c          285 g          532 t
ORIGIN      
        1 tttgttattt atataaaaat acttatctag ttactagcaa ttattagtag aaatggggga
       61 aatagagatg aataagggat tttacaaatt aaattcagtg gtattgaact ttgatattaa
      121 gaatgatgtt aacaagataa gatttaatca ttatataatg agaaaagaaa acatacaaag
      181 acttcaagga actctgccaa acggacaatt ttatatgaca gtgagaagag ctgctacaga
      241 tttacaactt tctatttcta ctataagtag gcttgtaaaa gagtttttgg atttagggat
      301 aataagatta gtgtctaagg gtgtaaaagg taatcgttct gtatatagtt acgtaagtat
      361 agagtttaat ggaagtttat ttgatgatag taaatatatg gaacttgact gtgtatgtaa
      421 tgatgaattt attgataata gtggcataga gtttgattgt gatagcaaag ataattcttt
      481 taatggagat ataaatgtag aaactgtgca ttgcattaat gagtatttgt ctgatgatga
      541 tgtagagcat aattataaca atttccataa taaagatact ataaaggata aagccatttc
      601 taatattagc actatcaaaa aatatattga tgaatctttt gataaaaata aatcagaaaa
      661 ttctaactta caacaggagt caataaattt caactttaat gatacatgca atgaaataga
      721 taaaagaacg aataatagta tagaaaataa tcaaaataaa aggcctatga gattgagtga
      781 catcagtgtt ttaagtgata aaggtatgac aaataaaaag aattacttta atcataatca
      841 tggtatacaa aaagggacta aatctgtaac aaagaaaaaa gaatccttaa ataaatttaa
      901 taaaaaaaat atacagcaaa gcattataaa tatgctaaat aaaaaatcag gtaagaattt
      961 taaaatcgat tctccaataa gcataaaact tatcaatgaa aggctaaagg aaggctatgt
     1021 cttagaagat ttctacaaag ttattgaggt aaaagtggct aagtggaaaa ataccataat
     1081 ggagatgtat ataagaccag aaaccttgtt tagctataag tttgaatcct atgtaaatga
     1141 aaacatatct atgaaaagtc aaagtaatgt tcacccatgt aaagaaggca atagtaatga
     1201 tagcagtaat tatatacatt ctgattatac aacatatgat ggcagtgtgc gtgagagaaa
     1261 aaaatatgag aatgtaagat actggaatcc tatatgtgag atttaattag tttaagaatg
     1321 tatttatgat aaataagata ttaatagaga atagtgagct atagcaaatg atatatcaat
     1381 agttggtagt aagttatatt aagtaagata ttactatcag gtagtgaatt atattgaacg
     1441 atatatcaat aattggtagt aaattatatt aagtaagata ttactatcag gtagtgaatt
     1501 atattgaacg atatattaat aattggcagt aagttatatc aaataagata ttactataga
     1561 gtaatgaatt atattgaacg atatattaat aattggcagt aaattatatt aaataagata
     1621 ttactataga gtaatgaatt atattggacg atatatcaat agttg
//
LOCUS       DAEPXW010000236         1525 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.240, whole genome shotgun sequence.
ACCESSION   DAEPXW010000236 DAEPXW010000000
VERSION     DAEPXW010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1525
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.240"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            34..1314
                     /locus_tag="KRM55_003748"
     CDS             34..1314
                     /locus_tag="KRM55_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBH1595913.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
BASE COUNT          648 a          195 c          172 g          510 t
ORIGIN      
        1 atataaaata attaaagata aaaggagtat tttatgaaca tacttggatt aatagttgaa
       61 tataacccat ttcataatgg acacatatat catttatcta aatctataga aaaaacaaat
      121 gcaacacata ctgtagcaat aatgagtgga aattttctac aaagaggcga accagcttta
      181 tttgataaat acactagagc aaaaattgct gtcgaaaatg gtgtagactt agttatagaa
      241 ttaccaactt tatttgcttg tcaaagtgct gaaatttttt ctcatggtgc tataacaatt
      301 ttaaattcac taaactgcat aaattctata tgttttggta gtgaagaagg aaatacagaa
      361 attctttata atatagctga aattttagca aatgaaccaa atgaatttaa gttactttta
      421 aaaaaatatt tagatgatgg tctgttattt ccaacagcta gagctaatgc gctttttgat
      481 tatatacatc aagacaaaaa aaataacttt atacaaaatt attcaaagga acaattatca
      541 aaaacattaa attcatcaaa caacatacta ggtatagaat acataaaaaa cctcatccat
      601 ttaaacagta gtataaaacc atttactatc tccagggtcc aatcagaata taattccgaa
      661 gaaattgaga gtgatatttg ttctgctact gctataagaa cttcacttaa agaaaataca
      721 gacctttttc atttaaaaaa tgttattcca gaaaaaactt ataacatcct aaatgaaaaa
      781 atagataatg gttttttacc tatgtttgat gacttcttct ttgatatttt aaaaacaatt
      841 atacttagag atatggacac tttaaaagag tattttgaag taaatgaagg catagaaaac
      901 agaatctata aagatatctt tacatctgaa tttctacatg aactacaatt agcaattaaa
      961 tccaagcgat acactttaac caaaatcaaa cgaactctaa acaatatatt gctaggtatt
     1021 aaaaaaagcg acatgcaact tataaaaaac atagatacta taccttatat aagaatactt
     1081 gcttttaatg ataaaggtag agaaattcta aaagagataa aaaataaatc tgaaataaaa
     1141 ataataaaca agttttcaaa tatatcattt tcattagatg atacgatttt taaaacactc
     1201 ataagttatg atataaaagc tacaaatata tataattcaa tatattataa aaacaataaa
     1261 gatttagtaa aaggccctat ggatttttat actcatccaa tatatgtaaa gtagtttttt
     1321 aaaataacta tatttataaa aatcatttta ttaactcttt attatataag atacaatagt
     1381 cttactttat ttatgtacac atgcttttag gatgacaaca tcaacttaaa tattatgtta
     1441 ctttctaaat ttaagtaaat attgccatcc taaaaatttt acaatttagc ttcagattta
     1501 aaagtaaagt ttaaaatatt atatt
//
LOCUS       DAEPXW010000237         1477 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.241, whole genome shotgun sequence.
ACCESSION   DAEPXW010000237 DAEPXW010000000
VERSION     DAEPXW010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1477
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.241"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            50..1018
                     /locus_tag="KRM55_003749"
     CDS             50..1018
                     /locus_tag="KRM55_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBH1595914.1"
                     /translation="MNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDFIVPVFFC
                     IICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINKPTMVMDD
                     LVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLMIALFPFG
                     MVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICVSYLAIFE
                     VLKLLNVKVDSVYLKTIFISITYISLYFIIRDSCMSLQNFIIAKFRKLLYARILFLII
                     ILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     misc_binding    1170..1422
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT          543 a          128 c          228 g          578 t
ORIGIN      
        1 taaaaacaaa actttagtta gaaaatttat gatttatgga ggcagtgttt tgaatactac
       61 taaaaaatta actgaagcag ctttattgtc atctttattc atagtagtaa caattatagc
      121 tgtgagtact ggatttggat atgctattta cttagatttt atagtgccag tatttttttg
      181 tataatctgc ttgaaatgtg atttaaagta taccatttta tctggaatta cttcgctttt
      241 aataatttct ctggtacttg gaaatctagg aactgctatt tgggcaagtc agagtgtatt
      301 acttggtata atgtgtggct atctaataaa taagcctaca atggttatgg atgatttagt
      361 atatggttca gtatttgggg ttattgtaat ggtttttatt gatatatatg cttcaacatt
      421 aataggttat agttttatga aagaatttca aggatatagc aaatggattt attttaatgg
      481 gtatacaaat tttatttatt atttaatgat agcattgttt ccttttggta tggtgttttg
      541 catatattta ttaagtttaa ttttagggaa taaattgcat attttagatt ctaattctct
      601 aaaaaaattt ttaatattta agaattttag aagtttaaac caatttttat gttgctcaaa
      661 aaaagctttt tacatatgtg tttcttatct agccattttt gaagttctaa aactgttgaa
      721 tgttaaagtt gattctgttt atttaaaaac aatctttata tcaataacct atataagtct
      781 ctattttatc attagagact catgtatgtc actacaaaac tttataatag ctaagtttag
      841 aaaattatta tatgctagaa ttttattttt gataataatt ttattgctgt tttttatatt
      901 tgatgtaaca gttattggtt taataattat aaacgcattt ttaaataaga aaataaatat
      961 aagattgagt cagagtaata tagtcaataa acaaataaat cttttgattg aaaaataaat
     1021 tttgggtatt ggtaaaaaat ataaaaaagt agtataatgt aaaaaaacat gtatataata
     1081 ataaaaaagg ttgacaaaat ataaaaataa taatatatta tgagtaagtt aagaaaaatt
     1141 tcttgtaatt gatgaaataa tctgaatata taaatgctat gaagagaaga agtagggcta
     1201 gattttattt aacagagagt tccagtttgg tgaaatggaa taaattgatt tagtttgaat
     1261 acatctcaga gcactatctc tgaaagataa caaccattaa gagatatcgg attagtacac
     1321 gttatagtac acgagtatat gtaattgtac tctaagagat taatatcgtg agatattgat
     1381 gaactaaggt ggtaacacgt aagcaatgct ttcgtccttt taagaggatg aaagcttttt
     1441 ttattataaa aataaaaatt atagattata taaatat
//
LOCUS       DAEPXW010000238         1440 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.242, whole genome shotgun sequence.
ACCESSION   DAEPXW010000238 DAEPXW010000000
VERSION     DAEPXW010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1440
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.242"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(407..1246)
                     /locus_tag="KRM55_003750"
     CDS             complement(407..1246)
                     /locus_tag="KRM55_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBH1595915.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
BASE COUNT          581 a          205 c          126 g          528 t
ORIGIN      
        1 taattttatg taatttatta tttgtttata attatttatg tcgctttttt ctaaacctaa
       61 ttacagtagc ttattctaat atattggtaa ttagaaatac aggcgcatat aaaaacacat
      121 gactaaatac tgcattattt gaaaatacag aaattaactc attaggacta taatttttat
      181 ttagtatatt ttttgatact taccaatttt atctcttact tatcaatagt catcttttta
      241 aagatgatta taaattaaaa ctatcccatt aaataaaatt tgtcaagtta tactaaaaat
      301 aaaaaaagcc cagaaaaatt ctagactttt taacttaaat gtcaatattt ctttattaat
      361 tcaattacat ttataatact aaatactctc ttttatttta aatactttac tttaacattt
      421 catgtcttat ctttctaaaa tacaatcttg aatttacctc atagccaata acgatagacc
      481 aactactaaa atacatccag gtcataagta caattatttc agctatactt ccatagatta
      541 cttcatagtt agcatagtaa tttgtataat aagaatataa aaatgatact aaaaaccaag
      601 caaaagtagc aaaaatagca cctggcgcag attctttaat agttaacttt ttatttggag
      661 tgtatttata taaaagtgta aatatcacta ttattgttat tatacctaca gtgtatctta
      721 gaatatccca tatttttata aatatctcat ccaatcctac aagattaaaa ataaaataac
      781 ctattttttc cccataaact aaaaatatca tagataaaaa aataaggacc aaaagcatta
      841 ttgtaaataa aaatgatata gataaaattt taaaaaaaga cctagtttct ttaactttat
      901 aggctctatt cattccttta ataagagctt ttactgctct tgaaaatgtc cacatagtaa
      961 gtacaaaact gactgctaaa aatttcaggt ttctattgtc tattgcagaa actatgattg
     1021 aagataacac agcaaaagca ccttctggca tcatatttct aaacaaagct atatacttat
     1081 ttaaatgaag aatcggtata taagctatag aacttattgt aaatattaaa aaaggaaata
     1141 tggacaacat taagaagaaa gatacttctg ctgactttga acttaattca ctgtaattgg
     1201 attttgcaat tatatattca atcaatttct tatctatacc aaacataaat atcccctttt
     1261 ctatcaaatt aatttcatta tacaatatta attatactca gattcattct ataatataat
     1321 tatttaagta aaaataacac aaataaaagc tgaaaataac aattctacta acatttccat
     1381 attctactca atgaaagtaa attataattt tcagctaaat aaatattatt acaaaattat
//
LOCUS       DAEPXW010000239         1337 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.243, whole genome shotgun sequence.
ACCESSION   DAEPXW010000239 DAEPXW010000000
VERSION     DAEPXW010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.243"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            27..101
                     /locus_tag="KRM55_003751"
     tRNA            27..101
                     /locus_tag="KRM55_003751"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KRM55_003752"
     tRNA            116..200
                     /locus_tag="KRM55_003752"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KRM55_003753"
     tRNA            210..293
                     /locus_tag="KRM55_003753"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="KRM55_003754"
     tRNA            323..399
                     /locus_tag="KRM55_003754"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="KRM55_003755"
     tRNA            407..482
                     /locus_tag="KRM55_003755"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="KRM55_003756"
     tRNA            571..659
                     /locus_tag="KRM55_003756"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="KRM55_003757"
     tRNA            663..738
                     /locus_tag="KRM55_003757"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="KRM55_003758"
     tRNA            745..818
                     /locus_tag="KRM55_003758"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="KRM55_003759"
     tRNA            833..909
                     /locus_tag="KRM55_003759"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="KRM55_003760"
     tRNA            933..1009
                     /locus_tag="KRM55_003760"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="KRM55_003761"
     tRNA            1017..1093
                     /locus_tag="KRM55_003761"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="KRM55_003762"
     tRNA            1102..1177
                     /locus_tag="KRM55_003762"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="KRM55_003763"
     tRNA            1185..1258
                     /locus_tag="KRM55_003763"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="KRM55_003764"
     tRNA            1265..1336
                     /locus_tag="KRM55_003764"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          321 a          309 c          355 g          352 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatataaatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAEPXW010000240         1321 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.244, whole genome shotgun sequence.
ACCESSION   DAEPXW010000240 DAEPXW010000000
VERSION     DAEPXW010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1321
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.244"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            179..400
                     /locus_tag="KRM55_003765"
     CDS             179..400
                     /locus_tag="KRM55_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH1595916.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
     gene            400..663
                     /locus_tag="KRM55_003766"
     CDS             400..663
                     /locus_tag="KRM55_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH1595917.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            725..1297
                     /locus_tag="KRM55_003767"
     CDS             725..1297
                     /locus_tag="KRM55_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1595918.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
BASE COUNT          511 a          158 c          238 g          414 t
ORIGIN      
        1 gatatttatg aaagattaat tagaaaaatt ttagaggtaa aataagaaaa aaagatactt
       61 atttaatcat ttaatcttat taaagaccta ttaaaactac cagttataat atagaaccag
      121 tatacaattt ttaaaaataa tgctatttta aaattctaaa aattaaggag gataattaat
      181 gggatattta aaagaggata aacaagacta ttgttgtgaa tttgctagac catacatcaa
      241 tcgtcaaatt tatgatgaca catacaatcc aaaaacagca ttaaaaagag gtactttatt
      301 tcctgaatta gatttaatag agtcaaataa ctataatgat tggctatatg caaatcctaa
      361 aaatagagtt agagctaaaa aagggggtaa catgtactaa tgtcattaaa tagaagagaa
      421 cttttagaga gaatttcaga atatcaattt gcctgtatag aattaaattt atatttagat
      481 aacaatccaa gggataagaa agctcttgat tcatacaaca gatactgcga taaatttaca
      541 caagctgtgt gtgattatga atctaaatat ggagcattaa ctaattttgg atatgaatca
      601 agtgaatatc cttggtcatg gatatctgaa ccttggccat gggacaaatc attttataaa
      661 taaaattatt aaactttaaa attagattta ttattaaata tatattaagg aggagtaaga
      721 taatatgtgg atttatcaaa aaacactgga acatccagtt aacataagac aagcagaccc
      781 tagaatggca aaatatatca tgactcagtt gggaggacct aatggtgagt tggcagctgc
      841 aactagatat cttcaacaaa gatatactat gccaactgga aaatctcgtg cacttttaac
      901 tgatataggt acagaggaaa tggctcatgt tgagataatt tcttcagtgt tatatcaatt
      961 aataggcaat tgtactccag aagagcttaa ggctgctgga cttggtagta attatgctaa
     1021 ttttggacat ggtcttcagc cagtagattc taatggagta aactttacta caagttatat
     1081 taatgtcttt ggcgattcgg taactgattt acatgaggat atggctgctg aacaaaaagc
     1141 attggctacg tactatcaat taataaattt aactgatgac cctgatttga aagatatatt
     1201 gagatttttg ggtgagaggg aagtagttca ctatcaaaga tttggtgaag cattaatgga
     1261 tgtttatgag tttacagagt gcaagcatca gttttaatga agaattgaaa gtgaatggag
     1321 a
//
LOCUS       DAEPXW010000241         1283 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.245, whole genome shotgun sequence.
ACCESSION   DAEPXW010000241 DAEPXW010000000
VERSION     DAEPXW010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1283
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.245"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(361..852)
                     /locus_tag="KRM55_003768"
     CDS             complement(361..852)
                     /locus_tag="KRM55_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBH1595919.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT          494 a          166 c          120 g          503 t
ORIGIN      
        1 aaatttttta agtttatgaa gttataattt aatatatatt tattttattt gtgagtctat
       61 ttttatatat aatgaaaaat gtgataagta tccaaaagaa ttactggata taataggata
      121 gggtatttag ccttttaaga taaataaaaa tatctgcaac tatatattgc aaaaatttaa
      181 aactaattta tatatgctaa tataaatatt tataaagaca taagacaaat ttacctacag
      241 atttaaattt aacttatata ttttaaaagg ctaatataat atgtattttc ttctatacaa
      301 tcaaaaggct tcatatctaa gatatgtgat gacactaata ttcacaattt ttagtaatta
      361 tcacattata aaaaatatta cagctagtcc atcattagat gcttcttgta taaacttttt
      421 aagctcaatt agatttgccc atacatattc aaaaaaatca tcttcactct catcattcat
      481 aacaggataa atattatttt ctaacatctc attaatatta aatctttttc taaatgcttg
      541 ttcttccaaa ctgttcattg cttttgatag tttttttaca tcatttgctg taatcaacat
      601 gacaggaaat tctccatcaa tttccataag tatgtttcca cttagtacta atttgctaaa
      661 tatattatca tcatctccac caaaaggaca acctgtcaaa gtaaagtgaa tggcatgcca
      721 tgctttatca atattgatag tactattttc gttggcatct tcaaaaacaa aatcttgtaa
      781 attttcttct gcttgctgta atttaaaaac attctcttca cttattttag tataacatcc
      841 tatcattccc ataattacat tcctcctaag tagcgttttt ttaattgtaa cttataatta
      901 aacttagtta caataaaata tattgagaaa agtattattt catcttaaat ttaaatacct
      961 atattatcaa ctaaaattct gtgtttatag cgtaagtatt attttttcct aaaaattaaa
     1021 tgaatcagag gttctatagg caatattgac tataaataag aactattact ttttaaaaaa
     1081 aatttaagaa attatactgt agaatcatgc tctacttatt agctttaaat aaaaaataaa
     1141 tcatgttctc aaattaaata ataaataaca ataaatttaa attttaaact ataagagttt
     1201 ctgaagtgtt aataagcata ccaataatta tatgtgtaag aatttgattt aatagatatg
     1261 aataattttt acattaatta taa
//
LOCUS       DAEPXW010000242         1281 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.246, whole genome shotgun sequence.
ACCESSION   DAEPXW010000242 DAEPXW010000000
VERSION     DAEPXW010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1281
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.246"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            123..311
                     /locus_tag="KRM55_003769"
     CDS             123..311
                     /locus_tag="KRM55_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBH1595920.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(471..623)
                     /locus_tag="KRM55_003770"
     CDS             complement(471..623)
                     /locus_tag="KRM55_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBH1595921.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(721..1197)
                     /locus_tag="KRM55_003771"
     CDS             complement(721..1197)
                     /locus_tag="KRM55_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH1595922.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
BASE COUNT          423 a          206 c          156 g          496 t
ORIGIN      
        1 taagaaattc ttcaatatgt gtaaggcaaa tatatatttc tattgcaaat ttttgttatt
       61 tatgataata taaatatgtt tttagtcttt aaatagttat cattttaagg aggtgtgcgt
      121 agatggcaaa agtatgtagc gtatgtggta aaggtaaggt ttctggaaac caagtatcac
      181 actcaaataa acataataaa agaacatggt cagctaactt aagaagcgta agagcgatta
      241 tagatggagc tcctaagaga gtaaaagttt gtactagatg tttacgttct ggtaaaattg
      301 aaagagctta gtaaccacgt ttaaaagcct acttccgtaa gtaggctttt taatttaatc
      361 atttttactc tttctcataa attttaggat tatacttgaa atccattttg gtaattttat
      421 tgttactact ttcatcaata ctcaccccac actttatagt taaaactatt ttaacaaaaa
      481 aataataatg ctccacatcc aataagtatt aatgcggtaa gtgctgacca aatccagcca
      541 ggaagcaaca ttgacagaat tacagccatt cctgttgcta gacaaagtat tcctagcaat
      601 accttagact tgttatttct catggaacac ctccacatag aacctgtatc tataaatatt
      661 ttcatattca agtttatgcg acagttttcc attttagacc aataaacaca ttatgtaatt
      721 ttaatttttc atactggaat tattactgaa ctccgatata gattctacaa tatccaaaat
      781 tccttttttt ctacttaacc tttcaggtcc actatataaa acaactggta taactttagg
      841 aagtttaaaa tttttatctt ctatttcttc aagacttttt ttcataataa aacttttcca
      901 aatttgttct ctatacgatt tcaatcttgg gacaatttca gtatccattt ctgtttgaaa
      961 ttctaacact atataatgtg atactttgcc gcttttagaa aataccttat aaattatatc
     1021 aacttctttt cctttatatt cacatataaa agatgtttct aactctatat ttttaagagt
     1081 taattctttt gctattgaga cacttgtaaa attttgaatc aaacttaaaa aactttcttt
     1141 atctgaatac attcttctgt actcttctcg tttttcattg cttcttttta aattcataca
     1201 gttcctccta gactatagac cttctatttt ttagtaaaga tagtctataa attttatttt
     1261 ttaattttca ctagtgagta t
//
LOCUS       DAEPXW010000243         1255 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.247, whole genome shotgun sequence.
ACCESSION   DAEPXW010000243 DAEPXW010000000
VERSION     DAEPXW010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.247"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            94..1134
                     /locus_tag="KRM55_003772"
     CDS             94..1134
                     /locus_tag="KRM55_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBH1595923.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT          483 a          148 c          200 g          424 t
ORIGIN      
        1 tatgtttaga ttctattctt ttaattttag ttttcagaac atttgtattt atgttataat
       61 ttgtataaat atatttattt aggaggaaac aatatgaatt taaatttaac taatactata
      121 aatttaatga aaaaatattt ggacattcca agcccagctg gatatactga aaatgcagtt
      181 ttagaaatca aaaaagattt tgaaaattta ggtcttgaca ctattcttac aaaaaaaggt
      241 gcacttatag ctactcttcc tggtgaagat gattcaaatc aaataacaat atctgcacat
      301 atggatacac ttggagctat agtaaaagaa atatcatctg atggtactct taaataccat
      361 aaagttggtg gtggatgttg ggcggctata gagggagaaa actgtactgt tataactaga
      421 aaaggtaaaa aaatcagagg aagtgttgta tttaagtatg cttctactca tatatatggt
      481 caaacaaaag ctgccactga aagaaatgaa gaaacaatga ttattagact tgatgaaaaa
      541 gtatttacaa agcaagatgt attagattta ggaataagtg ttggggattt tgtatgccta
      601 gaccatagat ttgaggctac agaatctggt tttataaaat ctagatatat agataataaa
      661 tcagctgtag caatggttct tgaaatatgt agatatttta aagaaaacaa tttaacacct
      721 aagcatacta ctaactttta tataagtaat tatgaagaaa ttggacatgg tgtttctaaa
      781 tgtttacctg aaaaaacaaa agaatttgta gcaatagata tagcacctac tggaccaagt
      841 caaacatcta gtgaacatgg tgtaactata gttgcaaaag ataatttatc attatatgat
      901 tttaatttaa gaaacaagct tgtcgatgtt gcagaagaca ataatttaga ctacgctgtc
      961 gatgtattta ctttctatgg ttcagatgct tcagaagcta ttcgttgggg agaagatgtt
     1021 caaatagcat gtgttggtcc tggaacaaac aatagtcacc attatgaaag aacacatata
     1081 gaagctattg aaaatacact aaaattactt ataaattata tgcttaaaga ataattaatt
     1141 atatatttta ccaaagtcaa ttcttaacaa ataattaact ttaattttta tttttataca
     1201 aaaattggtt tttctataga cttaatttca atttactact attatataag taact
//
LOCUS       DAEPXW010000244         1241 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.248, whole genome shotgun sequence.
ACCESSION   DAEPXW010000244 DAEPXW010000000
VERSION     DAEPXW010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1241
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.248"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(468..1151)
                     /locus_tag="KRM55_003773"
     CDS             complement(468..1151)
                     /locus_tag="KRM55_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBH1595924.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
BASE COUNT          473 a          187 c           93 g          488 t
ORIGIN      
        1 aatcaattta tatattagtt atttatattt ggttcatttg agttaacata tacattattt
       61 actatattta gtatatttct attaacttat atattgatta ctgtatttta aattcttcaa
      121 ttaatttata tactgcttac taaatttaaa acattttaat taatttgtac actgtttact
      181 atacttgaaa tacttctatt aatctatata ttgcctacta tacttaagac attttaatta
      241 atttatacac tgtttactat acttgaaata cttctattaa tctatatatt gcctactata
      301 cttaagacat tttaattaat ttatacactg cttactatac ttaaaatact tctattaact
      361 tatacattgc ttactatatt ttaaattctt taattaatct atacaatatt tgctatatat
      421 aaagtatatc aaataacagc ttcatttttt tgtaaattta cagaaagtta attttcatta
      481 aatgaatcat ctttattgat aaacataatt ccaaagacca ctgccaaaat aaaaaaacat
      541 attagtattg atttttccac gaaaattttt gtaaaaaaag ttcctaaaat agctccagat
      601 ataaagaata taataatagc ataatactgt aaactctttt ttatcataaa aatattctta
      661 gtatgtatat aatgaaataa agtttctgta gcacttctta aatttccagt acacattgtc
      721 gttgcaaaac tattcccatt tacttttcta aaactctcta cttgcattga acaaataaaa
      781 gaaatagcaa catttacaaa catattaaat cttcctctag gaataaatga aacaataagt
      841 attgtaatca tttcaattat aatgataacc tgacgccaat gaatctttgt cttattattt
      901 gtaaaatact ttcttatctt ctcggctata aatacaccta acataaatgc caaaatagga
      961 atcaaataat aaaatgattc ctttacatta ccttctgcta tattaagccc aaataaaact
     1021 atatttccag tttgtgcatt agcaaagact ttacctctta ccacataagt ataaatatcc
     1081 aaaaatcctc ctgttattgc caacaaagaa cataaaaaga atgattcaga catctgactc
     1141 ttgcttgtca tatataaacc tctcgctttc taatgataga tacaaaatca aaatcatttt
     1201 agattctatt tttcattgat ataaaaaaat tatttatatt t
//
LOCUS       DAEPXW010000245         1234 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.249, whole genome shotgun sequence.
ACCESSION   DAEPXW010000245 DAEPXW010000000
VERSION     DAEPXW010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1234
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.249"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            30..497
                     /locus_tag="KRM55_003774"
     CDS             30..497
                     /locus_tag="KRM55_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH1595925.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMIISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            508..723
                     /locus_tag="KRM55_003775"
     CDS             508..723
                     /locus_tag="KRM55_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595926.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
BASE COUNT          446 a          142 c          155 g          491 t
ORIGIN      
        1 tatactttat ataaaggaga tgatatttta tgattacaaa attttttagt aatatattat
       61 cagtatttct atattttcta ttatcacttt taggagttgc tggtataata ttcttatgta
      121 tgatacctat gtttttatat gattttagtt ctgacaaagt aatcgcttta attgcaagaa
      181 tactatattt ttctgactac tttatagtca tcttattctt gatatttata attaatagta
      241 ctaagtattc cccattcgta cttgaaaatg taaaaaggtt taaggtaatg ggattttgtt
      301 tattgataaa cactataatt gaatgtatca atggttataa tttaaatact aataatataa
      361 gaatttttgg aactgatagt ggcggtatct caccacttat gattatctct tttatatttg
      421 cactaatgtg ctttgtaatt gcagaaacat ttgataaagc tataaaaata aaagaagata
      481 atgatttaac gatatagagg tgatgttatg gcaatagtag ttaacctaga tgtaatgatg
      541 gcaaaaagga aaatatcact taaagatttg gcagaaaaaa tagatattac aaatgcaaat
      601 ttatcaattt taaaaactgg aaaagcaaaa gctattagat ttaccactct aaacgaaatt
      661 tgcaaagctt tagactgtca gccaggtgat atacttgaat atgtagaaga tgaaaatgat
      721 taaaaaagag tgtttagaaa cactcttttt tattatacta tatgattttt attcttttac
      781 tatattattg acattaatat taactttgtt taaagtcata acaaaatatg ttctaagaaa
      841 gaaactgttc ctttatctat ttgttatcca ttacctataa gaactgtatc acactaaata
      901 atacttttaa attgataatt ttaccacaga ttcctatata cattcttttc tacctaatat
      961 ttatttaaac tgttagcaaa acatggaact ttttcattta cttatacctc catttatatt
     1021 attgcatagt ttatagctac gtgttataaa ttacattatt gatgatttta tctaacattt
     1081 gtaatctttt agatactctt tgaagttaca acactgttat actctaatta agtaaactaa
     1141 atctgataca agttggtgat tatatgaaaa gaaaactttc aacctatttt aaaggatata
     1201 ttttaggttt atgtatagca tttttattat ttac
//
LOCUS       DAEPXW010000246         1218 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.250, whole genome shotgun sequence.
ACCESSION   DAEPXW010000246 DAEPXW010000000
VERSION     DAEPXW010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1218
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.250"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            116..1192
                     /locus_tag="KRM55_003776"
     CDS             116..1192
                     /locus_tag="KRM55_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH1595927.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
BASE COUNT          474 a          173 c          216 g          355 t
ORIGIN      
        1 atataaaaaa taaattttat gttgacatag ttaattcagc ttgatattat agttattaaa
       61 aataaggaca gtaaaaacgc tatccatatt acaaactaaa aaggggggaa ttataatgag
      121 taagaaatta tttattcctg gtcctattga tgttaaagaa gaagtcttgc aaaagatggc
      181 tacaccaatg ataggacata gaggaaaaga tgcatctatg ctccaaaaga gtataagtga
      241 aaagatgcaa aaactattct atacaaacaa cacgatactt ttatccacgt catccggaac
      301 tggtttaatg gaaggctcca ttcgttcctg tacatccaaa aaggcagcag tattttcctg
      361 tggatccttt ggtgatagat ggtacaaaat ggcagtggct aataatgtcc cagcggatat
      421 atttaaagtt gaattaggag aggcaacaac gccagaaatg gttgataagg tgctttctac
      481 cggagaatac gatttaataa ctgtaactca caatgaaact tcaactggaa taagaaatcc
      541 aatagaagaa attggagaag ttgttaaaaa gtatgaagat gtaatctact gtgtagatac
      601 tgtaagttca gccggtggaa taaaagtcga ggttgataag attggaatag atatttgtat
      661 aacatcagta caaaaagcac tgggattacc accaggaatg tctatttgca cattttctca
      721 aaaagcaatc gatagagcta agcaagtacc ttttagagga gtatatcttg atttgttagc
      781 aatgtatgaa tacttaatca agaaaaacta ccaataccct tcaacaccat ctctttctca
      841 catgttcgct ttagatttcc aattagataa tatattagat gaaggcctag ataacagatt
      901 caacagacat gaagacatgg caaacttagt tagaaactgg gctaaaaaac acttccaaat
      961 ttttaccaat gaaaatcact tatccaatac acttactgtt atagaaaata ctcaaggtat
     1021 tagtgtatca aatttaaatt caaaattaca agaacgagga ttccaaatag caaatggcta
     1081 tggagattta aaagaaaaaa cttttagaat ttcacatatg ggtgactata ctgtcgaaga
     1141 tgtacaagaa ttattagata atattgatga tatattaggt tttaataaat aatattgtaa
     1201 aaatatgtat gttttaag
//
LOCUS       DAEPXW010000247         1178 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.251, whole genome shotgun sequence.
ACCESSION   DAEPXW010000247 DAEPXW010000000
VERSION     DAEPXW010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1178
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.251"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(237..1106)
                     /locus_tag="KRM55_003777"
     CDS             complement(237..1106)
                     /locus_tag="KRM55_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH1595928.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT          447 a          181 c          110 g          440 t
ORIGIN      
        1 aattctaatc aaccgtaaat aataatctaa aatacatcaa aaaataaact aaaaaatatc
       61 gaaaaataat ttaaaagaca tcaaaactaa atcttctaat cagcaattaa aagtctattt
      121 tcttagttta aaaaataaag atagattttt tcaaaacact ggataaatag gtaaaaaaat
      181 aaacagttag taaaataaat ttttactaac tgtttatttt tattgtttaa tatgtcctat
      241 aaatcctcta agtaatattt tccttgcaaa aattctgatt ctaaacctag atttttaaaa
      301 taatcaacca tgcccataca cgcaaatttt tctgtagaat aatgagtagc acctataaca
      361 ttaattaaat tatcttttgc tatttgatgg aactctaata ctggttcaaa atgttttaaa
      421 ggcttagtaa acccagtaat atatagattt ataccaagtt cagcaacttc tcttgctaca
      481 aatggataac ttcctccccc tgctgcaata gcaactaaac catcttttaa tacagaatct
      541 ccataatcat acaatttcac atcatgacca acagattttt taattaattc cttaatctct
      601 tctattgatt ttagtgatgt tttacatata actcctacct caattttatc gtcatattta
      661 caaaatggtt tgactatttc taaacccata gcttttgcaa aactaacaga agttgaatag
      721 tcactatagt tgtctagtgg agaatgtaat acataaaaag aaattctacg atttttcatc
      781 tcttccatat aagatagtgg tatgtcgtga aatggaaaac cttcatctga tgctatgtat
      841 cccattgcat gatgtgaaaa aattaaaata tctttttcat ctttatctat aacttgctta
      901 attatttctt tatcaggaaa agtagttgtg tatactttat taatattttg agcattatct
      961 aatactaatc ctatgtattt ttttctaaat tctggagtaa taaaatcatt ttcaaaattc
     1021 ataaaactcc aatcatcatt aatattttta atattaaatt ctaaatctaa ttttttataa
     1081 agttcaattg ccttaataat aaccactcct ttataataat attgaattac tacatattaa
     1141 tatagaaatt tccgataata aactttatac gtttaagt
//
LOCUS       DAEPXW010000248         1171 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.252, whole genome shotgun sequence.
ACCESSION   DAEPXW010000248 DAEPXW010000000
VERSION     DAEPXW010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1171
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.252"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            213..353
                     /locus_tag="KRM55_003778"
     CDS             213..353
                     /locus_tag="KRM55_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595929.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(350..721)
                     /locus_tag="KRM55_003779"
     CDS             complement(350..721)
                     /locus_tag="KRM55_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595930.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
BASE COUNT          455 a          116 c          140 g          460 t
ORIGIN      
        1 caataataga tttttttgtt attattacga gttttttatt gcaactgtag aataaaagta
       61 ttattatata attaagataa ttatctaggg aaattttgga taatcaaaat atattttata
      121 aaatcaaaat acaattacat aaactttatt aaaaatttgt tgggaatttc tgactaacat
      181 taagaacgta agtttgttgg gggatggtat atgtggaaaa gtcaaacact actgttacaa
      241 aaaaagaaaa aattgaagat ataggaatga aattagaaca tttattgagt gaagatatta
      301 ctttttatga attattactt gagattttgt ataaagaaaa agaagagaat taattctctt
      361 ctttaaggaa tctttttaaa taggcattat caatcatttt ttctatagct tctctatctt
      421 ctttttcaag agaatatatt ttttctaaga gcttttttgt tttttcactt actgataagt
      481 tctctatgat taatttatct tctttgctta tttttgtatt atcatttacg cctaataaat
      541 aatctgttga tgtttctaat gcttttgcta atctaactat tatttcactt ttaggttctc
      601 ttaaattatt ttcataacgt gacaagctag cctcagttat accgacttta gtagcaagtt
      661 ctttttgatt tatatctaat tcttttcgta gatttgctat tctatctcct aaactttcca
      721 tatgtacatc actccttacc gaaattataa gttattttga taaaaagtaa aataaaatta
      781 ccaaaaatat aaaaaaaaaa ggttaaaata ataaaatata ttgaaaatta ccatttgtat
      841 atgtataata tgaattatac aaatggtaat ttgatgagag gtggtatgtt gaaataagaa
      901 actgaattaa ttaataaata catagaaagt tttgaaaacc tttaattgag atataaacaa
      961 tatgtacaaa attttttgca agtaaaatta ccaaatgtat aaaataaatc agtagcatag
     1021 ataattttat gctttaatac attagattat ttaatttagt tataatggtc aaaaatgcaa
     1081 tctacaaata aaacaaagta ttatcaaaaa agtattcttt aagaaaattt tttattagag
     1141 atgtaattga tataaataat cgtattaaaa a
//
LOCUS       DAEPXW010000249         1122 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.253, whole genome shotgun sequence.
ACCESSION   DAEPXW010000249 DAEPXW010000000
VERSION     DAEPXW010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1122
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.253"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            39..1106
                     /locus_tag="KRM55_003780"
     CDS             39..1106
                     /locus_tag="KRM55_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBH1595931.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
BASE COUNT          481 a          111 c          195 g          335 t
ORIGIN      
        1 ttttatttaa aaatttatta atacaaagga gatttactat gaaaaataaa ttagtttaca
       61 tatgtattat gagtctattg ctatttgtag taggatgttc taataatcca aataaggaaa
      121 gtaccattaa aaaagactct aagaataacc aaagccaagt taaagaagaa aaaagagaac
      181 ctgtgaaaaa agatataact ataagtttcg ctggtgatgt aactatgggg aactataaag
      241 gttcatcata ttatggcagt tttgaccatg aatttaaaag acaaggagaa gattacaatt
      301 attttcttaa aaatgtaaaa cctgtatttg aaaaagatga cttaacagtg gttaatttag
      361 aaggtccact tactacagcg tcaaatgcaa aagaaaaaaa atttgcattt aaaggaaagc
      421 ctggatatgt aaatatttta aaatctggaa gtgtagaggc agtaagtatt gcaaataatc
      481 attcagaaga ttattttgaa gaaggaatga aagatacaca gtttatattg gacgagaata
      541 aaataaatta ttttggatta gggaaagatg ctgttgtaga tgtcaaagga attaaagtgg
      601 gtctattagg gtataatgga ttatcaactg aatataatga aaaaaattta aaacaaatgg
      661 aagatgatat taagtcctta aaaaagaaat cggatgttgt tgtagtgtac tttcattggg
      721 ggatagaatt agattattat ccagataaaa aacaaaaaga ttttgctcat tatgctatag
      781 acaagggagc agatttagtt atggggtctc acccacatgt gattcaagga atagaaaagt
      841 ataaaaataa gtatatagct tatagtctag ggaatttttg ctttggagga aataagaatc
      901 cttctgatac agatagttat atatatcaac aaacctttac tttttcagat aataaattaa
      961 cttcaattaa agagccaaat ataataccaa cttcaataac atctagtaac tccagaaata
     1021 attatcaacc aaaaatattg gatggaagtg agaaggatag agttttaaat aaacttgaaa
     1081 aaataagcaa agatttaaat aaataaaatg taaaaaaaaa ta
//
LOCUS       DAEPXW010000250         1117 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.254, whole genome shotgun sequence.
ACCESSION   DAEPXW010000250 DAEPXW010000000
VERSION     DAEPXW010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1117
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.254"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            183..935
                     /gene="cwlD"
                     /locus_tag="KRM55_003781"
     CDS             183..935
                     /gene="cwlD"
                     /locus_tag="KRM55_003781"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBH1595932.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT          497 a          112 c          167 g          341 t
ORIGIN      
        1 gaatatacgt tatcaaaatt tataatataa actaagtata atttattgta tagtattgaa
       61 tgttagataa acatagtgaa ttaaataggg acagaaatat aatatcatta cataataata
      121 tattaatacc aataaataaa gatatatcaa tattaaaaaa atttaaatgt ttgtactaat
      181 atatggaata ttatagtgtt tttataagta tacatataca gggtgatgtt gtgagaaagt
      241 acataaaaca tataattttt agttttgcaa tgatatgtct agtagtagta tccatatttg
      301 aaattaaaaa tatttctgaa gatgttatca agtatatgcc agtaacaaac aaaactataa
      361 ttttagatgc tggtcatgga ggcattgatc caggtgcatt aaataaggat aagagtacat
      421 ctgaaaagga tattaaccta gcaataacac ttaagcttag agagcttata gaatcaagtg
      481 gtggccttgt aatattaact cgagaagatg acagtagcct ttataaagaa gaaaataata
      541 aaactacaag acaaaaatat aatgagaatt tgaaaaatag aaaagaaata atatctaatt
      601 ctaatgccaa tatgtttgtc tctatacatc ttaatgcatt tgaacaatca aaatactatg
      661 gagctcaaac tttttatcct aaagacaaac aagacagtaa agaattatcg aagtgtattc
      721 aagaagaact taaaagagta gtagataaga caaacaacag agaagtcaaa ccaagggatg
      781 atatatatct tttgaaagaa aataatattc catcagtact gatagaatgt ggttttttat
      841 caaatgaaaa agagtgtaaa ctcttaactg atgaaacata tcaagaaaaa atagcatggg
      901 caatctacat aggaatacaa aaatatttaa gttgaaataa ctataaaaat aggtctaaat
      961 atgtaaatag cttgtattaa agcagttaaa atgcattaat ataggctatt tttattttga
     1021 caaaaaaata tttaaaataa aagttaaaaa gttgttgact tagaataata tagatgatat
     1081 tatatatgag tgcccaaaag gagcaccaaa ataagac
//
LOCUS       DAEPXW010000251         1115 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.255, whole genome shotgun sequence.
ACCESSION   DAEPXW010000251 DAEPXW010000000
VERSION     DAEPXW010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.255"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            445..912
                     /locus_tag="KRM55_003782"
     CDS             445..912
                     /locus_tag="KRM55_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1595933.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVKRLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSMDEVAKRMDVTVEYIESVLE"
BASE COUNT          444 a           72 c          173 g          426 t
ORIGIN      
        1 aaaatatcaa taattagaaa gattatgaaa actaaattag aagaactaaa aactatattt
       61 ttattaatta gaatatttga ataatctctt taatcatata aaatgcatat acttgtaata
      121 tttaaaggtg atattaatat tattagtgta tattaatatt cccttgaaat taaaaaaaca
      181 tagatatttc agtaatctaa aatagtctac aaaaataata gttttatcaa aattaataag
      241 aatacatata gatttaaacc taaaagtatg aacatgtctg ttttttacaa gattaaaatt
      301 tatattatat gataaaatta aattaactta actatttcaa taagacttat aatttttttc
      361 tttatactag accttattga aacctttata gtttaattct aattatatat tataaataaa
      421 gtatgtgtat attaaggagg taatatgaag tttttaaatg ttttaatagt agttgaagat
      481 attgagaaat caaaaaagtt ttattatgat gttttggggt taaaggtaat ctgtgatttt
      541 ggagaaaatg ttgtattaga aggtaatata tcattacaag aaaaaaagct ttggttagaa
      601 tttattaata agagtgacag tgaagttaag ttcaatggaa atgatgctga gttatatttt
      661 gaggaagata attttgatac ttttgttaaa agattgagta caatgaaaga tatagattat
      721 gttcatctag ctatagagca taggtggggt caaagagcaa ttagatttta tgatttagat
      781 gggcatatta ttgaggttgg agaaactatg tcatctgtgt gtagacgttt tttagatagt
      841 ggtctttcaa tggatgaagt agctaaaaga atggatgtaa ctgtcgaata tattgaatca
      901 gttttagaat agatggatta tattaaagta aaattgaggt gaaggctgta agtaaacttg
      961 tgtgaaaaca aatttgctta cagtttttat ttttctaaaa taaagaatat aatacttgtt
     1021 tagctttatt tgagttttta aaaatattat gatatttctt atatatttat acgaaagttt
     1081 agatttagaa aaaatatata aaagatagtt atatt
//
LOCUS       DAEPXW010000252         1028 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.256, whole genome shotgun sequence.
ACCESSION   DAEPXW010000252 DAEPXW010000000
VERSION     DAEPXW010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1028
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.256"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            178..684
                     /locus_tag="KRM55_003783"
     CDS             178..684
                     /locus_tag="KRM55_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBH1595934.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHDNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          412 a           93 c          158 g          365 t
ORIGIN      
        1 tctatatttt acacttataa aatatgaaaa ctacttattg cgaaagtaat tgatttgttg
       61 tattataatt tacatgaatt atgtagggca atcaaaagtc agtattataa gagtacatat
      121 attcaaattt ttaacaatta atttatataa ttaaaaaatg aagggtagga tgaagtcatg
      181 ggttttagag aagtaaaaat tgaggaatta cagtttaatc catttactaa gattggcaaa
      241 gaatggttac ttataacagc tggtgattca gaaaagttta acacaatgac tgctagctgg
      301 ggtggtgttg gagtatattg gggtaaaaat gttgttacaa cttacataag accacagaga
      361 tatacaaaag aatttgtaga tagtaatgat acatttacag ttgccttctt tgatgaaacg
      421 tatagagagg ctttaaatat ttgtggtact atttctggta gagatataaa taaaatagaa
      481 aaagcaggac ttacaccata ttttgtggat gatacggtag cttttgaaga agctaatatg
      541 attatagtat gtaaaaagct atatcatgat aatatgccac cagaaaactt tgatgctaaa
      601 gaaaatgata aaaaatggta tccagagaaa gactaccata ctatgtacat ttcagaaatt
      661 ataaaagttc ttgtaaaaga ataattataa taaaaaatat atgaaaagaa cttattataa
      721 gtaaatgact gtgctttctt atctgatatc taagtagatg ctagtaacta aataaatatt
      781 aattttaaat aaatactatt ataaaaaaga tgaactatat ttactatagt tcatcttttt
      841 atttatataa gcacttatat aagtagagat ttatttgaat aaaagtattt atttgaaata
      901 tttgagtata ctttataagt atttttatgc taactagaaa cacttaattt atggcatttg
      961 tatttgattt attttaatgt aaataatttc aaagttaatt ttattcaata tagtactata
     1021 aaagtata
//
LOCUS       DAEPXW010000253          908 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.257, whole genome shotgun sequence.
ACCESSION   DAEPXW010000253 DAEPXW010000000
VERSION     DAEPXW010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.257"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            90..749
                     /locus_tag="KRM55_003784"
     CDS             90..749
                     /locus_tag="KRM55_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1595935.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFFFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVVTVSNLDNMNVLLSGSLYRYEAIFLGKLMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
BASE COUNT          336 a           68 c          108 g          396 t
ORIGIN      
        1 taagtgtgtt ttttatgcta taattagtat gtatttttta tgatatattt tataaaaaat
       61 ataatttaat catttttgag gatattatta tgttagatgc atttataaca attgtttctt
      121 ctattataga aatatggtca tgtaaaaaag tttttgatta tactagtcag tcaaagaccg
      181 acttaaaaaa actaaatatg tatttcttct tttctgtttt tctcattatt tcttctttat
      241 atataaatat aggagctaat agtagaatat tgatatgtat atttgtaatg ttcgttttct
      301 ataagtctaa ctataaggtt aatatatata aatgtctggt aatctcattt ttttattggt
      361 taatattaat aggtataaat ggattaagta tgttattagt agtaacagta agcaatttgg
      421 ataatatgaa tgttttactt agtggcagtt tatatagata tgaagcaata ttcttgggaa
      481 agctaatgtt aggtatatta ctttatgttt ataaggcttc ttttaaaaat tttaaaataa
      541 gtaaaaaaga gatatacata tgtattccta tgatagcaaa tttattgtca ttttttgtac
      601 tttatgatta tattattaat cttgtaaaaa tctctcctga aagaagaact gcttttttag
      661 taatagtttt actattaata ttatctaaca tttcaatctt tgtattaata catataatac
      721 ttaagattaa aattaggaaa ataagataaa ttttaatacg attcatttaa attaaaagtt
      781 aataattact tttttatgta taattttaca tgaatttcta taaaagttat tttattaaag
      841 atagatatac ttatatatac ggatatgatt aaaaaaagtc tttttaactt taaaaattaa
      901 tgttaaaa
//
LOCUS       DAEPXW010000254          825 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.258, whole genome shotgun sequence.
ACCESSION   DAEPXW010000254 DAEPXW010000000
VERSION     DAEPXW010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..825
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.258"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            97..663
                     /locus_tag="KRM55_003785"
     CDS             97..663
                     /locus_tag="KRM55_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBH1595936.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT          321 a           68 c          149 g          287 t
ORIGIN      
        1 ataatttaat aaatataaat taaattatat gtgtatatat tgtactttaa tagtgatata
       61 ataataaaaa aatttttaaa gagggtgata ttacatatga gaaaacttga agagatatta
      121 gaatataata aatcatttgt agagaacaaa gaatatgaac aatatgtgac atcaaaacat
      181 ccaaataaaa aaatagtagt cttatcttgt atggatacaa gattaactga gcttttgcct
      241 aaggctatga atttgaaaaa tggagatgtg aaactaataa aaaatgcagg agctactata
      301 atgcatcctt ttggaagtat tatgagaagt gttttagttg caatttacga atttgatgta
      361 gatgaggtta tggttgtagg gcatcatgga tgtggtatgt gtaatgttga tacggataag
      421 ttacttggta aaattttaga tagaggaata tctaatgatg taatacttac acttcgtagt
      481 gctggaattg atacaaaaca atggttacat ggattcgatt ctgcagaaga atctgtaaaa
      541 gatagtattg atttaataaa agggcatcct ttaattccag atggtattat tgtacatggt
      601 ctaattatat cacctgaaac tgggaagtta gatgttgttg taaatggata tgaagataag
      661 tagagtatca taatgttata taatcaagat actgttgaat aagatgttgt ttcaaaattt
      721 attttgggac aactttttta tttgaaaata tatgaaaagg tttattttaa gctttacaat
      781 aaaaaatata agtagctgac taattaaaaa tcttactatt attta
//
LOCUS       DAEPXW010000255          747 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.259, whole genome shotgun sequence.
ACCESSION   DAEPXW010000255 DAEPXW010000000
VERSION     DAEPXW010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..747
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.259"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            50..433
                     /locus_tag="KRM55_003786"
     CDS             50..433
                     /locus_tag="KRM55_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595937.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
BASE COUNT          314 a           73 c          117 g          243 t
ORIGIN      
        1 aattttacag tattaatagt aaattatctt agaaaggaat gtgctttata tgtctacaga
       61 caaagttgtt ggaatcatag atgaagaaac ggcagaactt gcaggaattg aatatactgg
      121 taaaatttat gcttcttctg gtgttataaa acatataaag aaaaaacata gatgtcaact
      181 gagtaaggat atttttaatg atataataga cactataaaa atggtattaa agtcacctga
      241 atatatagga agtcatccta aaaaacctgg aaaaagtgtg gagtttataa aaaaaattga
      301 tgattatatt ttagtagcta cagaattaga tacaaaaaaa ggatatttat atgtatcttc
      361 aatgtatgct ataaaagaag caaaattaga aagtagagta aacagtggaa gagtaaaaca
      421 atatgatggt taacataata ttattaattt tccctaaaat attgaaaaat attattatat
      481 aagttataat attaatatac acgtagatat ttattagtta gatttgaggt tggaaaaggc
      541 acccaatacg ctactataga gtagttaata gagatgcagg atacgccgcc ctgccaaatc
      601 taattaaatt aaaaagagag gattaattcc tctcttattg tttttttgag atactaattt
      661 aatctataat agaaagattg aaggtcgttt atacaaaaaa attttcagtt atatacatta
      721 aactaattaa ataagatatt tataatc
//
LOCUS       DAEPXW010000256          680 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.260, whole genome shotgun sequence.
ACCESSION   DAEPXW010000256 DAEPXW010000000
VERSION     DAEPXW010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.260"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            90..>680
                     /locus_tag="KRM55_003787"
     CDS             90..>680
                     /locus_tag="KRM55_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1595938.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT          277 a           69 c          147 g          187 t
ORIGIN      
        1 atagattaag tgaaatgcta ataaattaaa aaagtgaaat atcaaaataa aacgtcaaca
       61 aattaaaaat tatatggggg aatatcaaaa tgttaaatga aacaagaaaa aaacaattaa
      121 ctgaagtatg ccaagactta ataagaaatg ctagttattc aggtcaagaa gaaaacgtag
      181 taaaagctat agaagaaaat tttgctttac taggttttga tagttggtca agagatagat
      241 atggaaatat agtaggatgt ataaaaggaa ataaaccagg taaaaaaata ttatttgacg
      301 ggcatataga tacagttcca gttccagatg caagtaaatg gagtgttcct ccttttgaag
      361 cgagaatagt agatgggaaa atatatggta gaggaacttc tgatatgaaa ggtcaagtaa
      421 gtgctatgat ggctgctgtt tcatattttg cagaagatac taacaaagac tttgaaggtg
      481 aattgtatgt agcaggtgtt gttcatgaag aaatatttga aggtgtttca gctagagaga
      541 taagtaaggc tgttcaacct gattatgttg taataggtga atcttcagaa ttaaacctaa
      601 agataggtca aagaggtaga ggagaaatag tagtagaaac ttttggtaaa ccagctcact
      661 ctgctaatcc agaaaaaggt
//
LOCUS       DAEPXW010000257          664 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.261, whole genome shotgun sequence.
ACCESSION   DAEPXW010000257 DAEPXW010000000
VERSION     DAEPXW010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.261"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(<1..>664)
                     /locus_tag="KRM55_003788"
     rRNA            complement(<1..>664)
                     /locus_tag="KRM55_003788"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAEPXW010000258          659 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.262, whole genome shotgun sequence.
ACCESSION   DAEPXW010000258 DAEPXW010000000
VERSION     DAEPXW010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..659
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.262"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
BASE COUNT          267 a           45 c           76 g          271 t
ORIGIN      
        1 atttcaataa taaattattg atataatata taaaaccatt gtaatataca ctaaaaataa
       61 gaatgtataa ggtggtaaat ttatataaaa aaggatatga gttgtaaaat attaaataat
      121 attgtactaa ttggaataat tttaacttta ttatagatta ttttaatact attagtactg
      181 atggtgtatt ttaaaattgg tataagcatt acaaatacga atatgccaac tgtaatatgt
      241 aatataagta gctatataca tatgtgctgt cccatatatt gtatcattgt ttatattaaa
      301 aagattatgt aaattggtat caatcaataa atcattttca gaagaaatac ctaaaaactt
      361 aaaaaatacc tatatgtgta tttagttaga tttgagattt ttacatttaa ttttatagtg
      421 acaatattat attattttta tgatgtctat ttatatgcaa ttactataat atcagaactt
      481 atagtatcat ttgtttcatt attaataagg ttttttactt tagttttgtc aattttatta
      541 aaaaaagtta ttgatataaa agataagaag gataaaacta tatgatggat ttcaaacata
      601 agagtggata tttatataat agatatttta tagttaattt tattagattt tatttaata
//
LOCUS       DAEPXW010000259          659 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.263, whole genome shotgun sequence.
ACCESSION   DAEPXW010000259 DAEPXW010000000
VERSION     DAEPXW010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..659
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.263"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..>659
                     /locus_tag="KRM55_003789"
     rRNA            <1..>659
                     /locus_tag="KRM55_003789"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          187 a          136 c          195 g          141 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaagg
//
LOCUS       DAEPXW010000260          618 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.264, whole genome shotgun sequence.
ACCESSION   DAEPXW010000260 DAEPXW010000000
VERSION     DAEPXW010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.264"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..>618
                     /locus_tag="KRM55_003790"
     rRNA            <1..>618
                     /locus_tag="KRM55_003790"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          173 a          137 c          176 g          132 t
ORIGIN      
        1 ttagtagcga agtagctgat ttcacactgt caagaaaagt ctctatcgag gttaaaggta
       61 cccgtaccgc aaaccgacac aggtgggtga ggagagtatc ctaaggccag cgagagaact
      121 gttgttaagg aactcggcaa aatgaccccg taacttaggg ataaggggtg ccaccatcag
      181 gtggccgcag agaataggcc caagcgactg tttaccaaaa acataggttt ctgctaagtc
      241 gcaagacgat gtataggagc tgacgcctgc ccggtgctgg aaggttaagg ggatctgtta
      301 gagcaatcga agcagtgaac ttaagcccca gtaaacggcg gccgtaacta taacggtcct
      361 aaggtagcga aattccttgt cgggtaagtt ccgacccgca cgaaaggcgt aacgatttgg
      421 gcactgtctc aacaacagac tcggtgaaat tgtaattccg gtgaagatgc cggatacctg
      481 cgacaggacg gaaagacccc atggagcttt actgtagctt gacattgggt cttggtacta
      541 catgtacagg ataggtggga ggctttgaaa ccaggacgcc agttttggcg gagccatcct
      601 tgggatacca cccttgta
//
LOCUS       DAEPXW010000261          559 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.265, whole genome shotgun sequence.
ACCESSION   DAEPXW010000261 DAEPXW010000000
VERSION     DAEPXW010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..559
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.265"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..>559
                     /locus_tag="KRM55_003791"
     rRNA            <1..>559
                     /locus_tag="KRM55_003791"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          151 a          115 c          184 g          109 t
ORIGIN      
        1 gattagctag ttggtaaggt aacggcttac caaggcgacg atcagtagcc gacctgagag
       61 ggtgatcggc cacattggaa ctgagacacg gtccaaactc ctacgggagg cagcagtggg
      121 gaatattgca caatgggcga aagcctgatg cagcaacgcc gcgtgagtga tgaaggcctt
      181 cgggtcgtaa aactctgtcc tcaaggaaga taatgacggt acttgaggag gaagccccgg
      241 ctaactacgt gccagcagcc gcggtaatac gtagggggct agcgttatcc ggatttactg
      301 ggcgtaaagg gtgcgtaggc ggtctttcaa gtcaggagtg aaaggctacg gctcaaccgt
      361 agtaagctct tgaaactggg agacttgagt gcaggagagg agagtggaat tcctagtgta
      421 gcggtgaaat gcgtagatat taggaggaac accagttgcg aaggcggctc tctggactgt
      481 aactgacgct gaggcacgaa agcgtgggga gcaaacagga ttagataccc tggtagtcca
      541 cgctgtaaac gatgagtac
//
LOCUS       DAEPXW010000262          536 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.266, whole genome shotgun sequence.
ACCESSION   DAEPXW010000262 DAEPXW010000000
VERSION     DAEPXW010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.266"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(153..452)
                     /locus_tag="KRM55_003792"
     CDS             complement(153..452)
                     /locus_tag="KRM55_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595939.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
BASE COUNT          202 a           71 c           54 g          209 t
ORIGIN      
        1 atattttata aactaatata ttttacaaat tgttgagtaa tattttatga tataaatcag
       61 aagaggcact tctataatag aaagtgctca actatgaata agattaataa tatatttgcc
      121 ttagatatat agacttttat aaatattaaa gattaatcaa atctgatgtt tgaaacttta
      181 tcccaattaa tcttccttga atagtcttct ggatgtgata atctaactat atgagttgaa
      241 ttatcatagc tgtaataaat tgtagtagta ccatcaactg gattcttttt gtatccttga
      301 tacacagcac tatttggtac tttcttttca acaaagctat atgcagatga agtatcaata
      361 gtttctattt tattaggaaa tataaacata taaaaagcta ctactataaa aatacatatg
      421 catgtaatac tataccattt aatccatttc ataaaattcc tcctacttta ccaaaatata
      481 ctattattat ttccatatat ttataatatt tatgcatacg ataaaatttt tatatc
//
LOCUS       DAEPXW010000263          523 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.267, whole genome shotgun sequence.
ACCESSION   DAEPXW010000263 DAEPXW010000000
VERSION     DAEPXW010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.267"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(143..343)
                     /locus_tag="KRM55_003793"
     CDS             complement(143..343)
                     /locus_tag="KRM55_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1595940.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT          204 a           73 c           48 g          198 t
ORIGIN      
        1 agttatttta aaaaagttag tttaagtttg acgcttttct aaagtaactt cttatttttg
       61 taattaaaaa taaatataat aaacaacaaa aaagagccct cgatagctcc ttttctaaaa
      121 tatatatatt taaattaaat aattatattc tatttacgtt ttcagcttga ggtcctctat
      181 taccttgagt tatatcaaag ctaacctttt cgccttcttc taaagttttg tatccatcat
      241 tttgtatagc tgagaaatgt acgaaaacat catcttctcc ctctacagat atgaacccaa
      301 atcctttttc attgttaaac cattttacta ttccgttttt cattataaga aaacctccgc
      361 attattaaaa aatacaaact aaaaaaataa gtctgttcta ttaatataac ataaatttta
      421 aataaaagca aataaaattt ttaaaaaaat taattacttt tagaatttaa taaaaattgt
      481 taaattatac agtgagaagt attgtaaaat ttgacgaaaa tgt
//
LOCUS       DAEPXW010000264          490 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.268, whole genome shotgun sequence.
ACCESSION   DAEPXW010000264 DAEPXW010000000
VERSION     DAEPXW010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.268"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..138
                     /locus_tag="KRM55_003794"
     CDS             <1..138
                     /locus_tag="KRM55_003794"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1595941.1"
                     /translation="KAYRVENELIIGKKKAYRVENELIIGKNQAYRLKNDLFIDEELN
                     L"
BASE COUNT          243 a           42 c           58 g          147 t
ORIGIN      
        1 aaagcttata gagtagagaa tgaattaatt ataggtaaaa agaaagctta tagagtagag
       61 aatgaattaa ttataggtaa aaaccaagct tatagattaa aaaatgactt atttatagat
      121 gaagaactaa acttatagat taaaaaataa atgacttatt tatagatgaa gaactaaact
      181 tatagattaa aaaataaatg acttatagat gaaaaatcaa gctcatagat taaagaataa
      241 ataacttatt agatgaaaaa ccaagcttat agataagaag tccatgctta taagccagaa
      301 aatgaatact ttaatagatt aaaaaataca tatttgtgaa ttatagaatg aatgactcca
      361 taaactagaa aatttataat aatatctata tgaaaattag aattatttta tcacaaaaaa
      421 attaagttaa ataaatatga aattacttcc aaatatactt ccaaaaacat gtaatcgcat
      481 atataatata
//
LOCUS       DAEPXW010000265          451 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.269, whole genome shotgun sequence.
ACCESSION   DAEPXW010000265 DAEPXW010000000
VERSION     DAEPXW010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.269"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..>451
                     /locus_tag="KRM55_003795"
     rRNA            <1..>451
                     /locus_tag="KRM55_003795"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          110 a          102 c          144 g           95 t
ORIGIN      
        1 actgtcaggt gggcagtttg actggggcgg tcgcctccca aaaggtaacg gaggcgctca
       61 aaggttctct cagtacggtc ggaaatcgta cgtagagtgt aaaggcaaaa gagagcttga
      121 ttgcaagaca tacaggtcga gcaaggatga aaatcggact tagtgatccg gtggttctgc
      181 gtggaagggc catcgctcaa cggataaaag ctaccctggg gataacaggc ttatctcccc
      241 caagagtcca catcgacggg gaggtttggc acctcgatgt cggctcatca catcctgggg
      301 ctgtagtagg tcccaagggt tgggctgttc gcccattaaa gtggtacgcg agctgggttc
      361 agaacgtcgt gagacagttc ggtccctatc cgtcgcaggc gtaggaaatt tgagaagacc
      421 tgtccttagt acgagaggac cgggatggac g
//
LOCUS       DAEPXW010000266          391 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.270, whole genome shotgun sequence.
ACCESSION   DAEPXW010000266 DAEPXW010000000
VERSION     DAEPXW010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.270"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            154..270
                     /gene="rrf"
                     /locus_tag="KRM55_003796"
     rRNA            154..270
                     /gene="rrf"
                     /locus_tag="KRM55_003796"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            276..364
                     /locus_tag="KRM55_003797"
     tRNA            276..364
                     /locus_tag="KRM55_003797"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Leu,seq:taa)
BASE COUNT          131 a           69 c           83 g          108 t
ORIGIN      
        1 taactctata tttttaaact tgtcaaaact tatggatttt taatagtttt ataaggcaaa
       61 aaatcgaata aaaaaagtat tgacacaata agacaaagat gttattataa tacttgtctt
      121 agaaaaaaag ttaaatgaaa atttagacaa taatctggtt ataatagcag agaggataca
      181 cctgttccca ttccgaacac agaagttaag ctctctagcg ctgatggtac ttggtgggaa
      241 actgcctggg agagtaggac atagccaggt gatgtgccga agtggcggaa ctggcagacg
      301 cacaggactt aaaatcctgc gggacttacc tctcgtaccg gttcgattcc ggtcttcggc
      361 accacaaatt attgtgggcc attagctcag t
//
LOCUS       DAEPXW010000267          378 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.271, whole genome shotgun sequence.
ACCESSION   DAEPXW010000267 DAEPXW010000000
VERSION     DAEPXW010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.271"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            182..298
                     /gene="rrf"
                     /locus_tag="KRM55_003798"
     rRNA            182..298
                     /gene="rrf"
                     /locus_tag="KRM55_003798"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            305..376
                     /locus_tag="KRM55_003799"
     tRNA            305..376
                     /locus_tag="KRM55_003799"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:337..339,aa:Asn,seq:gtt)
BASE COUNT          120 a           60 c           80 g          118 t
ORIGIN      
        1 atttatttga tgttattcat taagatatat gtgtagtttt tagagtgtta actctatgta
       61 aagtactaac ttcaattgat gaagtatata tcgtaaaaac aattactatt tagtacttca
      121 aaactattga catttaaaaa taaagatgtt aatataatac ttgtcttata aataggcaat
      181 atgtggttat aatagcaaag aggatacacc tgttcccatt ccgaacacag aagttaagct
      241 ctttagcgct gatggtactt ggtgggaaac tgcctgggag agtaggacgt agccacgtga
      301 atattccaag gtagctcaat ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
      361 agccccaccc ttggagcc
//
LOCUS       DAEPXW010000268          336 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.272, whole genome shotgun sequence.
ACCESSION   DAEPXW010000268 DAEPXW010000000
VERSION     DAEPXW010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.272"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
BASE COUNT          143 a           24 c           44 g          125 t
ORIGIN      
        1 aaaaatttta gtattaataa aaaagatatt acattaatat gaaaatatag gagattagaa
       61 gtgtttgata attacagtac atgttagata tatcattgta aattaacata gctttgaata
      121 taataatgtt cagaaggcaa tatttttgag gtctgaatcc aataataata tagtcttatg
      181 attgtagata tcaaaaaatg taagttacta ggaatacgtt ttgtagattt atatatgatt
      241 aataactaaa gctataaata aacaaaataa aaagagtatg tttcaaccta tagcttttag
      301 atttaaaata tactctttta ttaattatag ttgtat
//
LOCUS       DAEPXW010000269          315 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.denovo.273, whole genome shotgun sequence.
ACCESSION   DAEPXW010000269 DAEPXW010000000
VERSION     DAEPXW010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.denovo.273"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            complement(<1..268)
                     /locus_tag="KRM55_003800"
     rRNA            complement(<1..268)
                     /locus_tag="KRM55_003800"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           77 a           82 c           53 g          103 t
ORIGIN      
        1 ggctaatccg cgttcgctcg ccgctactta cggaatcgaa tttctttctc ttccttcagg
       61 tacttagatg tttcagttcc ctgagttccc ctcattaagc tatgtattca cttaatgata
      121 cttagacatt actctaagtg agtttcctca ttcggaaatc ttcggatcaa agtttacgtg
      181 caactccccg aagcttatcg cagcttatca cgtccttcat cggctcctag tgccaaggca
      241 tccgccctgc acccttaata acttgaccag ttaaaaaggt ttgatagatt agaagctatc
      301 aacttcgata atttt
//
LOCUS       DAEPXW010000270        43076 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.guided.027, whole genome shotgun sequence.
ACCESSION   DAEPXW010000270 DAEPXW010000000
VERSION     DAEPXW010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43076
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.guided.027"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            246..863
                     /locus_tag="KRM55_003801"
     CDS             246..863
                     /locus_tag="KRM55_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH1595942.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTTDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIIKPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            971..3502
                     /locus_tag="KRM55_003802"
     CDS             971..3502
                     /locus_tag="KRM55_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1595943.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIRE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3936..4637
                     /locus_tag="KRM55_003803"
     CDS             3936..4637
                     /locus_tag="KRM55_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH1595944.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4687..5760
                     /locus_tag="KRM55_003804"
     CDS             4687..5760
                     /locus_tag="KRM55_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1595945.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIV"
     gene            6030..7130
                     /gene="vanG"
                     /locus_tag="KRM55_003805"
     CDS             6030..7130
                     /gene="vanG"
                     /locus_tag="KRM55_003805"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH1595946.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPILHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7127..7933
                     /locus_tag="KRM55_003806"
     CDS             7127..7933
                     /locus_tag="KRM55_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1595947.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7951..10089
                     /gene="vanT"
                     /locus_tag="KRM55_003807"
     CDS             7951..10089
                     /gene="vanT"
                     /locus_tag="KRM55_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH1595948.1"
                     /translation="MMRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10403..11023
                     /locus_tag="KRM55_003808"
     CDS             10403..11023
                     /locus_tag="KRM55_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH1595949.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11189..11725)
                     /locus_tag="KRM55_003809"
     CDS             complement(11189..11725)
                     /locus_tag="KRM55_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH1595950.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11838..12512)
                     /locus_tag="KRM55_003810"
     CDS             complement(11838..12512)
                     /locus_tag="KRM55_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH1595951.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            12715..14589
                     /gene="asnB"
                     /locus_tag="KRM55_003811"
     CDS             12715..14589
                     /gene="asnB"
                     /locus_tag="KRM55_003811"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH1595952.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(14681..16117)
                     /locus_tag="KRM55_003812"
     CDS             complement(14681..16117)
                     /locus_tag="KRM55_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH1595953.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVNRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            16446..17024
                     /locus_tag="KRM55_003813"
     CDS             16446..17024
                     /locus_tag="KRM55_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1595954.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            17063..17641
                     /locus_tag="KRM55_003814"
     CDS             17063..17641
                     /locus_tag="KRM55_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1595955.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            17727..18356
                     /locus_tag="KRM55_003815"
     CDS             17727..18356
                     /locus_tag="KRM55_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1595956.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            18346..21105
                     /locus_tag="KRM55_003816"
     CDS             18346..21105
                     /locus_tag="KRM55_003816"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH1595957.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            21192..22754
                     /locus_tag="KRM55_003817"
     CDS             21192..22754
                     /locus_tag="KRM55_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBH1595958.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAIDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            22755..23891
                     /locus_tag="KRM55_003818"
     CDS             22755..23891
                     /locus_tag="KRM55_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH1595959.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            23955..25031
                     /locus_tag="KRM55_003819"
     CDS             23955..25031
                     /locus_tag="KRM55_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBH1595960.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            25009..26247
                     /locus_tag="KRM55_003820"
     CDS             25009..26247
                     /locus_tag="KRM55_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBH1595961.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            26301..27389
                     /locus_tag="KRM55_003821"
     CDS             26301..27389
                     /locus_tag="KRM55_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBH1595962.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            27417..28208
                     /locus_tag="KRM55_003822"
     CDS             27417..28208
                     /locus_tag="KRM55_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBH1595963.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(28323..28877)
                     /locus_tag="KRM55_003823"
     CDS             complement(28323..28877)
                     /locus_tag="KRM55_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1595964.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            29073..30275
                     /locus_tag="KRM55_003824"
     CDS             29073..30275
                     /locus_tag="KRM55_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBH1595965.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            30351..31331
                     /locus_tag="KRM55_003825"
     CDS             30351..31331
                     /locus_tag="KRM55_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBH1595966.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLISVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            31578..32531
                     /locus_tag="KRM55_003826"
     CDS             31578..32531
                     /locus_tag="KRM55_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1595967.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRESIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            32521..33477
                     /locus_tag="KRM55_003827"
     CDS             32521..33477
                     /locus_tag="KRM55_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1595968.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFVIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            33474..34229
                     /locus_tag="KRM55_003828"
     CDS             33474..34229
                     /locus_tag="KRM55_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1595969.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVKKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            34321..35286
                     /locus_tag="KRM55_003829"
     CDS             34321..35286
                     /locus_tag="KRM55_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1595970.1"
                     /translation="MNKKAAIVATVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
     gene            35767..37626
                     /locus_tag="KRM55_003830"
     CDS             35767..37626
                     /locus_tag="KRM55_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1595971.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(37918..38517)
                     /locus_tag="KRM55_003831"
     CDS             complement(37918..38517)
                     /locus_tag="KRM55_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1595972.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(38620..39417)
                     /locus_tag="KRM55_003832"
     CDS             complement(38620..39417)
                     /locus_tag="KRM55_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-binding protein"
                     /protein_id="HBH1595973.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPASLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(39530..39635)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(39727..40713)
                     /locus_tag="KRM55_003833"
     CDS             complement(39727..40713)
                     /locus_tag="KRM55_003833"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH1595974.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            41197..42927
                     /locus_tag="KRM55_003834"
     CDS             41197..42927
                     /locus_tag="KRM55_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBH1595975.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
BASE COUNT        16588 a         4680 c         7280 g        14528 t
ORIGIN      
        1 caaaatgaac tttttagttc atgaggcact ctttttgtac gaaataaaat atatttttat
       61 tatttcaaca atgaaaaaga tgcttgtttc tattttgaga cagtataatt tttatgtaac
      121 tttaatttta gtaaatataa agttttaaaa ttgataaaat aggaggaatt tttaatataa
      181 aagggtaaat aaagggttta gagggcataa tatagaataa attaatatat ttaaggaggg
      241 tttttatgtg taaaaaaacg tatttattag tggtaagtat gcttatagcg ggtttattaa
      301 ctgcatgtag tgggagtcca actacggatt caggacaagc acaagataat acaaaaaagg
      361 aggcaaatgc atcaaataac gctttaaaag atgaaaaaaa taatgaaaat ttaatggaac
      421 aagattttaa agtgccatac acagatgcaa taaacatatt taaagataaa tataaggatg
      481 ctgatatagt agatttaagt cttgagagag atttaaataa atttgtttat actgtggaag
      541 gtgtagatga taataatgaa tataagatga aaattgatgc taatacaaaa gatgtattag
      601 aagataaaac agaaaagttg gattcagaag atttaaatgg agttgctaga aaagaaaaat
      661 tagatttaaa tgacataatt aaacctcaac aagctatgga aattgcatta aaagaacaaa
      721 atggaatggt taaagaatgg agtttagaca aagatttaga tgttactttt tataaaataa
      781 gaatagataa agataaaaat gaatatgaca taaaagtaga ttctaaaaag ggaactgtat
      841 tgaaggtaga aaaagaagat tagaagattt aaactatctt taaaataatt tcttttttga
      901 ataaattttg tttaaaatat aacaagcagg gtataaagag actaaataac tattttagga
      961 ggagtacggt atgtcattga aatcactaaa aataaaagaa aatttatatt gggtaggttc
     1021 acttgaccct gatttaagag tatttgacat aattatgtat acaccttatg gaactactta
     1081 taattcatat gtattaaaag gaacagaaaa aacagtttta tttgagacag ttaaagataa
     1141 gcattttgac aattatattg aaagattaaa tgatttaaat atagattttg aaaaaataga
     1201 ctatattgta gtaagtcata ctgaaccaga ccatgcagga agtgttgaaa agcttttgga
     1261 tttagctaaa aatgcaaaag tagtagcttc agaaacagca attaaatatc ttaaggaaat
     1321 cgtaaacaaa gactttgaat atgttgcagt tacagatgga gatacattat caattgggga
     1381 caaaacttta gaatttttct ctgtacctat gcttcattgg ccagatacca tatacacata
     1441 tataagagag gataaaactc ttgtaacatg tgattcattt ggtagtcact atagtaatga
     1501 taagatagta aatacacttg atgaaaatga agaaaaggat tacttggatg ctttaagata
     1561 ctattatgat tgtataatgg gtccatttaa accatctatg gtaactgcta tagaaaagat
     1621 aaaagattta gatatagata ctgtatgtcc aggtcatggt ccagtattaa ctgaaaatcc
     1681 tagaaaaatt atagaccttt attacaactg gagtgtaaat gaacaaataa agttagaaaa
     1741 agaagttaca atttgttatg tttctgcaca tggatataca aaaattatgg cagaagctat
     1801 aaaagcatat attgaaaaaa atagcaacta taaagtaaat ttatttgatg taatagagca
     1861 taagcaagaa gatattttgg caaaaatagc agtatcacaa ggtgtattat ttggaacacc
     1921 aacaatatta ggagatgcgt taaagcctat atgggatata ttaatatcgt taaacccagt
     1981 tcttcatggt ggaaaagttg cttcagtatt tggttcatat ggatggagtg gagaaggtat
     2041 agaaaatgct atggagagaa taagtcagct tagaatgaca gcagtaaaac cttttgctgt
     2101 taactttaaa ccatcaaatg aagagattga taaattacat tcttatacag gtaaattcct
     2161 agataagtta aattctactt ttggaagtaa aaagaaaact aagaaattta aatgtgtaat
     2221 ttgtaatgaa gtttttgaag gtgatagtgc tcctagtgta tgccctgtat gtggagctaa
     2281 ggaagaccaa tttatagaag ttgaagaaga tgaagttact tttagaaaag atactgatga
     2341 atatttcgta atagtaggaa atggagcagc tggtttttat gcagcagatg ctataagaaa
     2401 aagaaataaa acttgtaaga taactatgat ttctaatgaa gatgagttga cttactatag
     2461 acctgcactt tctgatggta taaatgaaga acttggttca gatttctaca tggaagataa
     2521 agattggtat gataaaaata atatagtagt aatattagga acgaatgtag ataaattaga
     2581 tgaagtgaat aaaactatta tagtgaatga tggagctatt aaatttgata agcttgtaat
     2641 agctacagga agtagaaact ttataccacc aattaagggt catgatttag aaaatgtgtt
     2701 tactcttaga aatataaaag atttatatag tgtaaaagaa gcactagaaa aatctaagaa
     2761 agttgtagtg attggtggcg gtttattggg acttgaagct gcatgggaat ttagactaaa
     2821 aggattagaa gtagtagtag ttgaagccat ggatagcata ctatcaaaac aacttgataa
     2881 agaaggcagt aaaatattag aacaatgtgt aagagataca ggaatagatg taagattggg
     2941 tgtagcagtt gatggtattg aaggtgatgg aaaagctcaa aaagttgtat ttaaagatgg
     3001 agatagtgtc gactgtgata tggtagtatt ttcaattggt gtaagagcaa acactcaaat
     3061 ggttcaggat acatctgtaa aaattgacag aggtattgtt gtagataaga cattacagac
     3121 aaatgttaaa gatatatatg cttgtggaga tgttgcacaa gtgggaaata ttagtttagc
     3181 aatatggcca tcttcagtag aaatgggaaa aatagcaggg gcaaatgcaa gtggagataa
     3241 tttgacattt gaaagtgaag tatatccagt ttcattagat gcaatgaatg taaaagtatt
     3301 tagtattggt aatatacaaa attttgataa agaaatttca tcaaaagatg aaggtcaaag
     3361 aatatataaa aaattattta tgaaagatgg ttcattagtt ggagctatac ttataaatga
     3421 tttaagctgt actgttaaat tgataagatt aatatctgaa aaaggtgatt ttgaggatat
     3481 tatgaaggct gatatactat aatttaaata cattaaaata aaaaggagtt gtctcaaaat
     3541 tgattttttt ctaatcaaat tttaaattca actccttttt tgaattttta tataaaataa
     3601 catggaaatt ttagtaatgt ctgtggttac atacataggt ttaattgttt tttatatgga
     3661 ttgtctctgg tataataaat tgaattgtgt ttgactgata gatattttta ttgaaagtta
     3721 atacctgtta tgcgataata aggacgtgtt aggggagttt ttataataac aattaatctc
     3781 agtttttgtg ttccaatagt agcatcaaca cattctgatg tagtagttct tttcttataa
     3841 aaattagtta caaatatgct tgtaattatt tgatatgtaa atttaccaat attataaatg
     3901 atgacctcga taataaggag agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg
     3961 atgatgaaaa agaaatagca gatttaattg aagtatattt aaaaaatgaa ggttttacag
     4021 tatacaagtt ttatacaggt aaggaagctc tagaatgtat tgaatctaaa aatttggata
     4081 tggctatttt agatattatg cttcctgata ttgatggatt tcatatttgc cagaaaattc
     4141 gagaaaaata ctattatcct atcattatgt taacagctaa aattgaagat atagacaaga
     4201 taatgggttt aaccataggt gctgatgatt atataacaaa gccatttaac cctttggaag
     4261 ttgttgcaag agtaaagaca caattaagaa gatatatgcg atataataat tcttatgaac
     4321 aacagtcgat aattgttaat gagtatgata ttaaaggatt gattatcaat aaagaaacac
     4381 ataaatgtag tttatttggg aaagaagtag cattaacacc gattgaattt tctattcttt
     4441 ggtatttatg tgaacatcaa ggaaaagtgg ttccttctga agaattgttt gaagctgtat
     4501 ggggagaaaa atatcttgat aataataaca cagttatggc tcatataggg cgattacgtg
     4561 aaaaaattca tgaaccttct aaaaacccga aatttataaa aactgtatgg ggagtaggtt
     4621 atacaattga aaagtaaaaa tattaaagtc aatcctgact ttactcaagt gagaaataaa
     4681 atttttatga gaacagcttt aatggcattt atagccatta ttttcatatg gattttatat
     4741 tcttttatat tgtatggtaa gttttctatc tggatagtat cattctttga aaatgctttt
     4801 cgtatggaat ataaagctgc attgaattta tatcagcaga ttttccgtaa tagcatggag
     4861 ctcttcatga tactagctat ggtgattgtg ttttttataa tattccgtgt ttatttaaat
     4921 tggtttacaa aatattttag tgaaataaat caaggtattg actctcttat caaagaagat
     4981 gttggagaag tggctttatc tccagagtta ttggcaatag aaaagaaaat aaactcaatt
     5041 aaacatatac ttgaacaacg taaatttgag acacaaatgg cagaacaacg taagaatgaa
     5101 cttattgttt atcttgcaca tgatttaaaa acaccactta catcagttat agggtatctg
     5161 acactacttc gagatgaaag tcagatttct gaagaactgc gaaaaaaata tttatctatt
     5221 tcgttggata aggcagagcg tcttgaagat ttaattaatg aattctttga aattacaagg
     5281 tttaatttat caaatatatc acttgaatac agtacagtaa gcttaactcg tatgcttgaa
     5341 caactaacat atgagtttaa acctactttg atgagtaaga atttaaaata tacactgaat
     5401 gttacaccaa atatgatgat aaggtgtgat gttaataaaa tgcaacgtgt atttgataac
     5461 ttattacgaa atgctgttta ttatagtttt gaagatacta ctattgaaat aacagctgta
     5521 caggaggatg attatataaa gcttaaattt atgaatcata gcaatacgat tccagaggaa
     5581 aaacttgagc gtatttttga acaattttac aggttggata catctcgtaa ttcaaacagt
     5641 ggtagagctg ggttgggact tgctatagct aaagaaatag tggagcttca taacgggaca
     5701 ataacagctc atagcgagaa caatataatt acctttaagg ttattattcc gattgtatga
     5761 aatttgtaag aatttaagta taaaaaaata ggaaattctt taggataaat aaataaagag
     5821 cactcttgtt attgatataa ttactgtatc aaaacaagag tgcttttatt ttgatacagt
     5881 aattatatca atagaaaaat gtgaaaatat attatgtgga acagatgcaa ttgtaagtga
     5941 aggttgattg gatttgaaat agaaaaagta ttttaacatg tttctgtaga ttgtataaaa
     6001 ataaataaat caacaaagga gaatcaaaga tgaataataa aaaaattgca gttatatttg
     6061 gtggaaactc aacagaatat gatgtatcat tacaatcagc ttttgcagta cttgagaatt
     6121 tgaatacgga aaaatatgat attataccaa ttggaattac aagggagggt aattggtatc
     6181 attatattgg agattataat aatatccaga ataacacttg gtttgaaagg gatactgata
     6241 taattccagt tattgtttcg cagaaccgtg tcaaaaatgg tattattgaa tttttaattc
     6301 ctgatgctgt ttctcagaat catattccaa atagtgctat tgaatcatgt gaaaatgata
     6361 ttaaatacac taaacttgat tttgtatttc ctatattgca tggaaaaaat ggagaagatg
     6421 gaacagtgca ggggttattt gaattggcag gtatacaggt tattggatgt ggtactcttt
     6481 cttcagcatt atgtatggac aaagacaaat cacataaact tgttcattca gaaggtatta
     6541 aagtaccaaa atcaatatta ctaaaatact cagataaatt taatgtggct gaactgtcaa
     6601 aagacttaac ttatccatta tttataaaac ctgtgcgtgc aggttcatca tttggtatta
     6661 gtaaaattta taaaaaagaa gagttacaag tagcagtaga cttggctttt gaacatgata
     6721 atgaagtaat aattgaggaa aatattgatg gttttgaggt agggtgtgca gttttaggaa
     6781 acgatgactt acttgttgga agagtagatg aaatagaatt gtcaaaagga ttttttgatt
     6841 atacagaaaa atatacattg aaaagttcaa aaattcatat gccagctaga attgatttgg
     6901 attgtgagaa aagaatacaa gagacagcaa aaattattta tagaactctt ggatgttctg
     6961 gatttgctag agtggatatg tttttaactc catctggtga aattattttt aatgaagtca
     7021 atacaattcc tggctttact tctcatagtc gttatccaaa tatgatgaaa ggtattggat
     7081 tgtcttttga agaaatattg gacaagataa ttgaggtgta cataaaatga tgaataatat
     7141 tttattagat aaaaataaag aagataaaat gacaaatact atcttattga ctaaagataa
     7201 agtttatgat gggaatctaa ttctagtaaa tgctttttta ccagttaaaa catctgaaga
     7261 tatagattta attcctgtag atacaaggtt tccaagtatt cttatgaaac gtgaagctac
     7321 aaacatttta caaaatattt taaaaagtat atgtggaata aatgaaatag tacctgtaag
     7381 tggatatcgt actgcagaag aacaacaaga tatatattca agttctctgc gtgacaatgg
     7441 aaaagacttt actaaaaagt ttgtagcact tccaaatcac agtgaacatc agacagggct
     7501 tgctattgat ttagggttaa agaaagaagt tatagatttt atctgccctg aatttcctta
     7561 taatggtatt tgtaatgagt ttcgtaaggc agcactacat tatggtttta tagagcgtta
     7621 tcagtgtaaa aaagaagaaa taacaggaat atctcaagaa ccatggcatt ttcgttatgt
     7681 gggatatccg cattctgaga ttatcaataa aatgaatctc gctcttgaag aatatataga
     7741 atatattaag agattttcgt atacaaattg tttaaaaata gaagataaag aaaaaattat
     7801 agaaatcttt tatgtgccta ttcatactaa agaagaagtg agaatctcta tacctgaaca
     7861 atgtgtatat caaatatcgg gtaacaataa ggatggtttt attgtgacat tttggagaaa
     7921 tagaaaggac taagaaatgg aggaacaaga atgatgagga ataaatctta tgcagggctt
     7981 gattatttta ggattatagc tgcattactt ataattgcaa ttcatacatc tccattatta
     8041 tcatatagta aaatggctga ctttgtgtta actagtataa ttgctcgtat tgctgtgcca
     8101 ttctttttta tgctatcagg cttttttcta atttcaacat ataattataa ttgtaataaa
     8161 ctgaaatctt ttctaaaaaa tgtattattt atttacggga tagctattgt aatttatatt
     8221 cccttaaata tttacactgg atatttttcc atgaataatt tagtgcccaa tattattaag
     8281 gacattgtat ttgatgggac tttatatcat ttatggtatc ttcctgcatc aattattggt
     8341 gcaagtattg catactttct tgtaaaaaaa ctaggtttaa agtactcact agtaatcact
     8401 attgttattt atgtaattgg tatgtttggt gatagttatt atggtttttt agaaaaaata
     8461 ccactattaa agaatttata tgggtatatt tttgaagtat cagattatac acgaaatggt
     8521 atattttttg cacctgtatt tttcatactt ggtggaataa tatctaataa atctaattat
     8581 atgtcaacta aaaatagctt gattggattt cttatatcat tcttacttat gttatgtgag
     8641 ggaatgtttt tacataaact aggggtacag cgtcatgata gcatgtatat tatgttattg
     8701 ccatgtatgt atttcttatt tacagcctta acatttttga aaggttctcg agctaggtta
     8761 ttgcgaacat catcattaat tatttatatt atacatccta tgatgattgt tgttattcgt
     8821 atgttttcta aaatattcgg aatacaaact gtcttggttg acaatagcct tattcattat
     8881 atagtggtaa gtatagcatc ttttatagct tctataatta ttatattgat tcttaaacct
     8941 ctaaaaaaag acttgaaagg agaacataag gtaaatacca atagagcttg gattgaaatt
     9001 gatttaaata atttggaaca taatgtaaag atgatacaaa aagctatgcc agaagattgt
     9061 gaattgatgg cagttgtaaa agctaatgcc tatggtcata gtgcttttga agtagcgact
     9121 tgtgcaaacc aaataggtgt aaaagcattt gcagtagcaa caatagatga ggggattgat
     9181 ttacgtcgat atggaatact aggagaaata ttgattcttg gatatactaa cccaataagg
     9241 gcaaaggaac ttcataaata caatcttaca cagagtgtta ttgaccttaa tcatgctatc
     9301 tctttaaaca aacagaaata caacataaaa tcacacatta aaattgatac aggtatgcac
     9361 agactgggtt ttgatgttaa tgatgtgagg tcaattttaa aggcatttaa attaaaatac
     9421 ttagatatat gtggcatatt tacacacttg tgtgtttcag atagtctgaa agatgaagat
     9481 gtagacttta caaataaaca aattgaatgt ttttataagt taattgattt tctgttaaaa
     9541 aaaggtataa aaattcctaa agtacatatt caaagtagtt atggtttttt taattatccc
     9601 aatcttaagt gtaattatgt aagaattgga attgcattat acgggatatt aagttctcca
     9661 aatgatacga ctaaattgca acttgattta cgacctgttt tatccttaaa atcacaagta
     9721 attcttatta gaaaaataca aaaagatgat agttttggat atggaagagt ctttattgca
     9781 agcagagata gcgtaattgc tatattatct attggctatg ccgatggtat acctagaaat
     9841 ttatcctgtg gaaaaagtta cgtaataata aatggttgta gagcagcaat agtgggtcga
     9901 atttgcatgg accaacttgc tgttgatatt acagatatac ctaatgtaga agttggtaat
     9961 acggcaataa taataggaag agataattta tctgaattat ctgcttctga agttgcaaat
    10021 aactcatgta gtatatcgaa tgaattattg agcagagtag gaagaaggtt aaatgttata
    10081 aagaagtaac tcaattaaat agtaatattt gttgtactgt gtaatttatt ttactctgac
    10141 tagacatttt tagtaatatt atgtctaata tatatttttt ataacttaca tgacaattta
    10201 agttataaaa aggtgatgtt tcagattttt attttgaaac atcacctttt ttgttataat
    10261 atataataaa ataattatac cttaactgta aacttatata gattatttac tttttaatat
    10321 tagattcatt ttttgagatt ggtatataat aaacatatag agtatataat aatagttaaa
    10381 gttaaaaaag gggaaaagca atatgcagta tatacaagaa ctacttgatt tgactcaaaa
    10441 ttattgggtg ttagccacaa taatcggctt attaagtgca tttatagaaa gctttatacc
    10501 agccttacca cttgttgcta tagttacagc aaatgctgca atacaaggat tatttattgg
    10561 atgtttgtta tcatggattg gctcaggact tgggacaact tcattattct tattaataag
    10621 cagatttaat gatagtaagc tttttaataa gttgagaaat agtaaaactg aaaaagcaat
    10681 aagttggatg gataaacagg gatttaagtt attatttata gcgtatgcct gtccatttat
    10741 gcccggttgt ttagttacta tcgcatcagc ttttggtaaa aaagatttaa aagattttgt
    10801 gccagcaatg ttggcaggaa aatttgtaat gtttatagtt ataagttacg tggcaagtga
    10861 tatagaaggt tttataacaa gtcctttaaa gatagcatca tttatattat tggtgttttt
    10921 gtcatggaag attggaaata gagtaaataa aaatcttgaa aatcataatt atgatttcca
    10981 tcataaaaaa catcacaatg ataaagatga taaaatgatt tagcttgtac gaaataaaac
    11041 gtatcttaaa atgatttagt actaaattat tttaagatac gttttatttt ttgtattaag
    11101 gtacaaaatt tttagttctt ttgtaaacta aaatatataa aacttattta tacttagttc
    11161 aaaatattgt tatttatttt ttctacaact ataataaaat ataaaattga tatccaatca
    11221 aaaaaataac tatgaaattt aatagcttag atatgaattt ttctgttttt gagttagttt
    11281 ttataggtag taaagaaatg tttatggtaa tgggataaaa caattcaata ccttctttag
    11341 taataaggtc aagacacaag tgagatagat atcctattat aaacccactg gacaaacatg
    11401 agaaaactat attattgtta gtgaagattg tcagagattt aaaaaaacta taaataagta
    11461 ataaggcaat tagactgtga gtaaaccctc tatgtctaaa cctacttcca aataatttgt
    11521 atattaacat aaatttttta cttatgtaag aacctctcat atctatatct ggaaataaag
    11581 aacctaaata tgcaaaataa atataaatta taattaatac tattttatat gcaatatcgt
    11641 atttaactag gtatagattg tttataaagg ggagtatcaa aagtgcgaat atataacctc
    11701 ccctttcatg tgtttctttt atcatataaa aatcctcctg aatcgtcact ataaacatta
    11761 tattggtaaa tttagactat cttttattat attatatagc aaacataagt ttttttcaaa
    11821 aggattttaa tatttaatta atcttgagat tttaaatttt tgtaattttc taaagcacca
    11881 ttccaattta ctacattaaa ccagttgtca atgtattcat ttcttctatt ttgatatttt
    11941 aaatagtaag catgctccca aacatcaagt cctattatag gagttaggtt tttacttaca
    12001 gggctatcct gatttggagt agtcataata gataatttgc catctttagt agctacaagc
    12061 caagcccaac cagaaccaaa gacatctaaa gcagattttt ggaactcttg cttaaatttt
    12121 tcaaaagaac caaagtctct atcaatagct tcttttaaag attcagaagg tatggttttt
    12181 tctggcgtca ttatatcaaa aaagaattta tgattataag ctccacctgc attatttctt
    12241 acagttgtag caatatcttt aggtaaagaa tctaaatttt gcaataattc acataaagaa
    12301 taattataaa gctcaggata tttttcaaga gcagcattta atttatcaac ataagcttga
    12361 taatgcttat catgatgcag tttcattgtt tctttatcta tataaggttc aagtgcatca
    12421 tatgcataag gtaatggttt aaccttaaat ttgttatttt caggtgtaaa agcaaatgaa
    12481 gttatgcact gtgagattat aaataaagac ataataactg gtattaatat ttttttcttc
    12541 ataaaaatca cctcctaata tagtatttct agaaataaaa aaaatatgaa atattaacag
    12601 ataatttata agaatttaat agcaatttca ttttaaattg aataagtttt aaagccaaag
    12661 acaaaactat gaaatataga ataagactaa aggacagaaa ggaattttga ttatatggac
    12721 ggcaatattt caatttatta taaaggtgat atatctaaaa aagaagatat taaatttaaa
    12781 ataaaagaat ctgtaaataa tacaagactt tctagtagaa tagagtataa ggatgaggaa
    12841 aaaacttttg attttgaaag atttaatgta attgatgcta tttatggaaa taaaccattt
    12901 gaaaaagatg gaaaagttat tgtttttaat ggaaatatat ataactatca tgaaataaaa
    12961 gaagaattaa ttaaaaaagg acacaatttt actacaaatg atgatattga agtcttattg
    13021 gcatcttata tagaatttgg taagaattgt gtacataaga ttaaaggaat gttcaacttt
    13081 ataatctatg atagagaaaa tgaaagtata tttggagcaa gagatttatt tgggataaaa
    13141 ccactttatt atataaataa ggaaaatgca ataatttttt cctcagagta taagttttta
    13201 cttgaatata tgaaaaattt aaatataaat gaaagaagct tacaaagtta tttttcattt
    13261 caatatgtac ttcctgaaga tactatgata caaggaataa ggctgatacc agcaggtcac
    13321 tattttaggg tagaaaatgg tatactatct ttaaagagat ataataaact tgagtttaga
    13381 agtagtacaa aattttttta tactaaaaat cacttaggca atagagatgt gaacgaggat
    13441 gatataagaa atatagtagt agattcaata gtaactcata tggaagagga gaaagaaatt
    13501 ggaacatttt tgtctggtgg aatagattca tctattataa ctactgtggc ttcacaaatt
    13561 aatccaaata taaaatcttt ttctgcaggc tttagtgtca aaggatatag tgaattagaa
    13621 gtagcaaaga aaacagctga taagttaggt atagaaaata tccagattaa tataacacaa
    13681 gatgaatata taaaatcatt accgaatgta atttattctt tggatgaccc tatagcagac
    13741 ccttcagaag taggtcttta tttcttaatt aaagaggcag gtaaacatgt taaagtagca
    13801 ttgtctggag aaggagcaga tgaattattt ggaggatata atatatataa agagtatagt
    13861 actatgaaat cagttgtcaa ttcacctact tatattaaaa gtatattagg aagagtttca
    13921 gaacttatgc caaacataaa aggaagaaat tatctttata gagctacaac accattagaa
    13981 aaaagatata taggaaatgc aaaagttttt gaaaacagcg aagtaaaaag attctttttt
    14041 aagtataagg aaaagaatat atatgaatac ctgttgtcta atttgtatag agatgcacaa
    14101 aaaaataatt acgattatat aagtaaaatg caacatatag atgtgaatac atggcttcaa
    14161 ggcgatatac ttcaaaaaat tagcaaactt tctacagctg agcaggttga acttagagta
    14221 ccatttttat ataaagatgt atttgatgta gcaaaaaatt taagaatgga gcaaaaaata
    14281 aataagaata atacaaaagt tttacttaga gaggcgttta gagaaatagt cccagaacat
    14341 gttgttcaaa ggaaaaaatt aggatttcca actccaataa gagtttggtt aaaagattct
    14401 ctaggggata ttgtaaagga aactatttat aattcaaatg tagatgaatt tatagataaa
    14461 aaatatgcaa taaaactttt agatacgcat cttaaaggtc atagagataa ttcgagaaaa
    14521 atatggacta tatttacatt ttgtctatgg catcaattat ttattgagca taaaaatgtc
    14581 gagtattaat actgttttca atattaatca gagggcaaaa gcatgcaatg ttttcaccct
    14641 cctgattatt atggaatagg ataagtagaa ttttgattga ttagtttact atctcaataa
    14701 aattattggc aaatattttg acaagactac tttcaacagc taaatttaag ttttgtccat
    14761 catcatatcc agcggaaatc aatcctagca agtttccaaa catatccaaa agagctcctc
    14821 ctgaactacc actagagatt ggagctgtaa attgtatcat ttgaaccgtt tcaaaatcac
    14881 gaaaagctga gataattcca tctgaaactg tattaaaaag acctaaaggg cttccaattg
    14941 caactatttt ttgacctctc acaggttttt tactgacttt aacaggtatt ggcttgcatt
    15001 ttctattaac ctttatcaca gctaaatcat aatctgaatg gtattttata atttggtaag
    15061 atgtataaac tttatcatca ttttcaaatc taactaaaaa tgaataccca tcattgacta
    15121 catgaagatt cgtaagtata taaccttcat tatttattac tactccagaa ccgctcttaa
    15181 acggtttatt ttcgttattg cacacaacaa tcataacaac agaagctgat aactttgcaa
    15241 ggtcttcata agaaagttct acttcctcat cttgtacaat ttttttagat gttagatttg
    15301 tgttattaag tgtattttta gagttaggtt tattcgtagt aggagaagtc ttattggtat
    15361 tttcactgta atttatattt gtaatatgcc tttcaaaagg tatttctaat atatttggag
    15421 tcttcctaga aagttcaaat agagtagaaa attttgaaca ttcaggatat aaatcaagaa
    15481 tatctttatt tggatttata tataaaatat cacacccaag ttgtgataaa aaatataaga
    15541 aaaaaagttc ttgcctttta atatttccaa agtatactat ctttggtgaa atagtagtct
    15601 tcaccttgtt ataaaataat ttaggtagaa aatagtctat ccaacacaaa agtttaactg
    15661 caaagttttt gatgatagag gatgtacaat ttggcatact tgtggaaaat aaatctaaag
    15721 tatttttaaa tgcaatcttt ttagtccaat ttaaagtgtc attttctatt ttacatggaa
    15781 agtcgatatt atataaatcc caactgttaa acttagaact atcataaata ttaaaaattt
    15841 taagcatctt atctgtttgt tctttgtcaa aatttatttt tagattgttt aatctaatat
    15901 agggaattgt aggattatta aaaaaataag tatctatatt tttaattttt tctatgtatt
    15961 tatcaattga atcatcaaca cctatatatc ttgtaaagta gacttcttta atatatgaag
    16021 aactcttatt tttataggta gtatcagata taaattcaat tagaggttca gtagactttt
    16081 ttattgaaat ctttaatggt ttaatagtac aaatcatatt ttttctccta taataagatg
    16141 atataatcta ttataaaaca acttaaaaca atatagtaca ataattttgt agtttcaaaa
    16201 taaaatatgt acttgtttat ataaatgata tataattaca tattaaacat agcttttatg
    16261 catttaataa agtatgtaaa atctatgtaa aaagtaagaa atataaacat ttttttaatt
    16321 atattttaaa aatatcaagc aagttttctt cacaaatgaa taaaaaatgt tataatatga
    16381 ttaaagaaaa agataaataa ttagcaagat ttgtttagct aaaattaaca agggagcgat
    16441 aaattatggg tataacatta tcaaaaggcc aaaaggttga tttaactaaa ggaaatccag
    16501 gtcttaaaaa tattttagta ggtttaggat gggatactaa caagtatgat ggtggatttg
    16561 actttgattt agatacagca gcatttttaa caggagcaag tggaagtgtt actaatgatg
    16621 gagattttgt attttacaac aatttaaaac atacatctgg agcagttgag catctaggag
    16681 ataacagaac tggcgaaggt gatggagatg atgaacaaat agttgttgat ttatctaaga
    16741 ttcctggaga aataagcaag atttctttta ctgttacaat tcatgatgca acagaaagaa
    16801 gacaaaattt tggacaagta agtaattctt atataagaat agtagataaa gacacaaatg
    16861 aagagttaat aaagtatgaa ttaggagaag attttagtat agaaacagct atagtagtag
    16921 ctgaaatata taagcacaat ggagaatgga agtttaatgc actaggttct ggctttgaag
    16981 gtggtcttgc tgcattatgt ggaaactttg gaataaactt ataatttcaa ctataacaat
    17041 aaactaaagg gggatatttt ccatggctat agtattaaaa aaaggacaaa aaatcgattt
    17101 aactaaggga aatccaggtc ttaaaaatat aaaacttgga ctaggatggg atacaaattc
    17161 atttgatagt ggctatgatt atgatttaga tgtaagtgtt ttcatggttg gagaatctca
    17221 aagagttgaa aaagatgaag attttatatt ctacaataac ttaaaacatc catctggagc
    17281 agttgaacac ttaggtgata atagaactgg tgaaggtgat ggagatgatg aggaaatatt
    17341 agtgaattta gagacaatgc caaagcatat acaaaagata gctgtaacag ttacaatata
    17401 tgaggctgct gaaagaagac aaaattttgg acaagtaagc aactcatata taagagtatt
    17461 aaattctgaa aatgatgaag aaatattaag atatgactta ggtgaagaat ttagtataga
    17521 aactgcaatt acagtatgtg agatatataa gtataatgga gaatggaagt ttagtgcagt
    17581 tggagcagga tttgaaggtg gcttagaagc actttgtaga aactatggct taaatgttta
    17641 atttaagcaa tataatatat taaatataaa taacctatac aaataatgta taggttatat
    17701 tatataaaat tttgtggagg tttagtatgt cgattaattt atcaaaaggt gataaaatag
    17761 atttaaaaaa atctaaccca ggactgagta acatacttgt aggtctagga tgggaccctg
    17821 tgcaacaatc tggaggaggt ttttttaaat cgttatttgg tggaggacaa gctgatatag
    17881 attgtgatgc atctgtattt atgcttaatc aagaaggtaa attaagtgga ataaaagatt
    17941 taatttattt tggaaatcta aaaagtgcct gtaaatcagt tttgcataca ggagacaatc
    18001 taactggtga gggtacaggt gatgatgaac aaatcctagt taatttggat aaagttccat
    18061 caaatattca taaattattg tttgtagtaa atatatacaa ttgtgtagat agaaaacaac
    18121 actttggaat gatagaaaat gcctatataa gagttgaaga ccaaggtaat aagaaagaga
    18181 tagcaaaata caatctatct gataattatt ctgaaaaaac tactcttata gtaggagcta
    18241 tatatagaaa agatggaagt tggcaattta aagcaattgg tgaaggaaca aaagatgcgg
    18301 gtcttaaaga agtaatgcaa aatttagaca ggattgagtg tgcatatgga atttaataat
    18361 gatatcaaat attataatgt agataaagaa gaagttacaa aagacttatc tgttaatcct
    18421 gaaaaaggtt tatcagaatc agaagtcaag actagaagag aaaaatatgg tttgaatgaa
    18481 tttactccaa aagaagaggg tagtttttgg gatgatttaa aggaaagttt aagtgaacca
    18541 atgatagtta tcttgattat tgcagcagta gtaagtgcag taattgggga aactcatgat
    18601 gcaataggga ttgtaggtgc tatagcaata ggtatagcaa taggtatgat tacagaaggt
    18661 cgttctaaga aagcagcaga ggctctttct aagttgactg aaaacataga agtaaaagta
    18721 ttgagagatg gggaagtaca tcaaatttct aagagtgaat tggtaccagg tgatatagta
    18781 tatattgaaa ctggtgacat ggtacctgct gatggtagac ttatagaaag tataaacctt
    18841 aaaattagag aagatatgtt aacaggagaa tctgatgacg tatctaaaaa gtgtgatgta
    18901 gtagtttcta tggaagagat agaatctaaa ggagcagtag tagtacagga gccaatacct
    18961 gcaaaacaga taaatatggt gtttggtggt acacttgtag cttatggtag aggagctcta
    19021 gttgtaactt caattggaga taatagtgaa atgggtaaaa ttgctcaaaa cttatcagaa
    19081 acagatgagc aaactccact tcagataaaa cttggaaatt taggtggttt gatagccaaa
    19141 gtttctagtg cagtagcagg attactattt atatttatgg ttttccaaat gataagtaag
    19201 aatgtattaa atgtagatat gtctggaata ttaccgtttt tagaatcaat agacccagtt
    19261 aaaacagcat ttacagtatg tgttgcgttg atagttgcag cagtgccaga aggtcttcca
    19321 actatgataa atatgacact tgcaataaca atgcaaaaaa tggctaaaat aaatgcattg
    19381 gttactaaaa aagaagcttg tgaaacgata ggttctgttt ctgtaatatg ttcagataaa
    19441 actggtacat taactgaaaa tagaatgact gtagaagttg catatgttga tggcagatat
    19501 attgaaagtt cagaagagga aataaatagt tattttgaag aaaactgtat gataaactct
    19561 acagctgatg tagagcacaa tgatggtgat attaagtatt taggaagtgc tactgaatgt
    19621 gcattgcttt tatattacaa aaacgtagat tatagacaag ttagaaaaaa ttctaatata
    19681 gtagctcaaa atccttttac ttcagattca aagagaatga cttctgttat aggtcaagat
    19741 aatcaccatg tactattatc aaaaggagca ccagaagtct tacttgaatt atgttcacat
    19801 attcaaagag gaaaagacat agttccatta actgaaaata taaaacatga gattttagaa
    19861 gaaataaaga aattgcaaat aaaatcaatg agaactttag ggtttgcata taaagaaatc
    19921 tcacaagctg aagaagaagc agcagtaact gctgaaagtg atgctatgaa tgtaagtgca
    19981 atggaaaata atttagtatt tagtggtttt gttggtataa gagacccact tagaaaagat
    20041 gttatagagt ctgtaaatac agcaaataaa gctggtgttt ctgtaaaaat gcttacagga
    20101 gataatataa atacagcaag agctataggt gaagagttag gcctattaaa aaataatatg
    20161 agagtggttg aagcttcata tatagatact ttagatgatg aagaattaaa acaagagata
    20221 caaagtattt caatcgtggc aagaagtaaa ccagatagta aaatgagaat agtttcagct
    20281 ctgcaaaaga gcggagatgt tgttgcagta acaggtgatg gtataaatga tgctccagca
    20341 ctttcaaaag cagatgttgg tatagcaatg ggtatatctg gtacagaggt atctaaaaac
    20401 gcggcagaca taattttaac tgatgatagt tttagtacca ttgtaaaagg tattaaatgg
    20461 ggtagaggaa tttatgataa cttccaaaga ttcgttcaat tccaattaac tgtaaatgta
    20521 attgcatttt tagtggctat aatatctcaa gttatgggac aagagatgcc atttactaca
    20581 atacaattat tatgggtaaa catcattatg gatggaccac cagcactagc attaggttta
    20641 gagccagtta gggaccatgt gttaaataga aaacctgttg atagaaaagc caatataatt
    20701 tctaagtcaa tggtgtatac aatagtatta aatgcatttt atataacagc aatactaatg
    20761 ttacaatcta catttaattt cttaggagtt gatgaagcgc ataagggaac agtaatgttt
    20821 gcgttatttg cttttagtgc actgtttaat gcatttaact gtagagagtt taatgcagat
    20881 agtatcttcc ctaattttac acataacaaa ttagcactac aaataatagt gttgacagga
    20941 attgcacaag taatatttac tcagctattc caagatttct ttaactctgt agcaatggat
    21001 tttatgacat gggtaaaagt tttatgtgta gcagcaagtg taattgtggt taatgaagtt
    21061 gtaaaatgta taataagact ggtaaaacca aaaaagactg cttaaaacaa attttttaga
    21121 agaaaacaga ctgactcaaa atatgaattt tgggtcagtt ctgaataaac atttaaattg
    21181 ggaggatagt tatgggtgac tcaaaggtat ttgaaaaaat attctccagc caatcagata
    21241 gaggaaatta cactccttca aagggatatc taagttattt tatttcgtat attggtttag
    21301 aagatgaagt tttgtacaat ctcgagatat ttaagacaaa acaaaatatt gatagcaaaa
    21361 aagatattgc tttatttact gatgttatag caaatcctag tgattttgat attataaatt
    21421 attttaaaag tggacttcaa aaatatagaa ctagcatgga agatgtagat ataaatattt
    21481 tgggatttga agagattgat tataaaataa agcaagcaat agatagagtg ttaaaagaag
    21541 aagaaaaaga atttactaat gatagagtta aacaaaattt tatagtgaaa ataatggcat
    21601 ggataaaaat ttatatcggt gctttagata taaataaaaa tgaagctcca aaagtaatat
    21661 tttatggaga tataaaaaaa catgaagttt atttactctt aatattatac ttggcaggtt
    21721 ttgatgtttt atatcttaat ccaaattcaa agagtaatat agatatttta aaatcagaaa
    21781 gatacaatat agagtttgaa gaagccaaca taatagaaga aaaaatttct tttgaagaaa
    21841 gggttatttt aggggaaaaa atagataaaa gttctgtaaa aaaagctttt actgttgggg
    21901 cagaagcatc aaagcgtata agtgaggaat tgttaaatga tgcaggattt ataaaacctt
    21961 ggcaactcca agatagaaaa ataaaaaatc tacttctaag ttcaactgtt gatgaaatat
    22021 caatatactg gaatcaacca cttaaattaa gaccaggatt taagtttaat gatgctattg
    22081 tagaagctcc aaattttctt tctaagatta atggaatata taacgataag aatgaatata
    22141 ttaagttttt agatttatta agagattcgg aaagttcaac atttattgaa tttaatggag
    22201 atgtagatag attttcaaaa gcttttacaa gagaagcttt tagtttatcc tttttattgg
    22261 attcaaaagg tgcaatagat aaaaactctg ttttaaataa taaagattat tccatatcaa
    22321 cactagcatt gaatcaacaa attatgattt tagagaaagt ggaagagttg ttagaaggaa
    22381 gtatgttttt gaatggttta agtggagaag acaagataaa aggtctattt acagtacttc
    22441 acatggataa gaaatttgtt catatgatga acaatttcga ttactcactt ataaacccaa
    22501 aattgattat atacatgtac aagagtattg tatttgataa agaaatagtt tttcttatgc
    22561 ttttacttag taagattgga tttgatatta tcatattatg tccaggagga gaaaacaata
    22621 tagagaatgt tataaataac caattgattg atgtacacag attggataaa atggtatatg
    22681 accttaaatt aaattcgctt gaaaatgata tacctttact taaaaaaatt tttggaaaga
    22741 ggagacgatt ttagatgggg ataaatataa atagtttttc aaaagataag aactctgtag
    22801 aggttactga gaatttgcct acagcagttc aagaagaaaa cttcgatata atggaatata
    22861 caaataataa aaaaaatgaa ctgagaaagt ctaaggaagt tgaggcattg acatccctta
    22921 tagaagtaga aaatccagat acgattttac agtttggtag gaaagcatct gaaggagtag
    22981 caagagtttc tgatagcctt ttaaatacaa taaaattaaa tagaaatgaa gaaaattcta
    23041 aaatgctggt tcatttaact aaaataatgg acaagtttga tttagacgat tttcaagaaa
    23101 ctaaggaacc aaatttcgtt caaaaacttt tcaaaaaagc taataatgcc attgaaatga
    23161 tgtttcaaaa gtatgaaaca ttgggaggag aagttgagaa aattcaaatt gagcttgagc
    23221 aatacgaaag agatatagca ctttctaata agcagatagg tgctatgtta aatgaaaact
    23281 ttgagtttta caatgaactt caaaaatata ttgttgctgg agaaatggca atagaagaaa
    23341 tggataatga aatactacct ttctttaaac aaaaatcaga gactagtgga gaccaaatgg
    23401 atgttgtcaa ttatcaagaa ctattaaaag tttatgatat gttaaatcaa agagtctatg
    23461 atttaaggat agcagaaaat atagctatcc aaacaatacc tatgcttaga ggtatgcaac
    23521 ataataatta tggtttaatt agaaaaataa atagtgcatt tgtcgtaact ttaccagtat
    23581 ttaaacaatg tttatctcaa gctatattac ttaaaaagca agaattacaa gcaaaatctc
    23641 taaaagcact tgatgacaaa actaatgaat tattgcttag aaatgcacaa aatgtaagta
    23701 ctcaaagtgc acaaatagct agaatggctg gaacaagttc tgttcaaata gaaacattgg
    23761 aaaaaatgta caatactatc aaatctggta tagatgaaac tatgagaata gaagaaaaca
    23821 atagagcttt aattaaggat aatacaaaga gattggaaga attaaatacg actataattt
    23881 ataataagta gtattatatt aagggctaat ttgtataaag ttggcccttt ctatgtatat
    23941 gaggaggcta gacattgaaa tatttcgatt atatctgcaa agatgatttg gagagaattt
    24001 ttttgaagga gccagaagat tttagtgcta agactgaaaa agatgtgttg aaatatgcac
    24061 tgggcgcttt tttatacgtt ccagctactc aatataatat gatttataag agcattatag
    24121 gggatgttaa gggagttaga ccattagcta tttgtttaga agatgctgtt ggagtaaatg
    24181 gagagttaga ggctatagag aatcttagat taattttaaa aaatattagc aatgaaagta
    24241 taactaataa agatggaata ccactaattt ttgtaagaat aaaagatgtg gagcaactgt
    24301 tgagaattaa agagattata attaaaaata gtcattttat aacaggaata ttaattccta
    24361 aagcaaattc ggagttaatt gaaaattgta tagaagcttt agattctatg aatcttcaag
    24421 atatgtatgt tattccgata gtagagacaa aagaatttat atataatgaa aaaaaagaac
    24481 ttagttttac taatttgtac aatgctattt taagacataa gtcaagaata ttaagcatta
    24541 gagtaggcat aactgatata ttagggatgt atggtataag gagagataaa aacttttcta
    24601 tatataataa tttgatttgt tcttcattta tattagatat aatcacatat cttcaaagac
    24661 cagagttaga tatacctata agtggtggag tatcagaatt ttttgatatg acgaataaag
    24721 atataagaaa taagtatata gaagaaatat tattggataa atatcatgga ttaattggaa
    24781 agaccgtaat tcatccaatg caaattcaaa ttgtacaagc gctatctaca gtatcatatg
    24841 aagattttac tgatgctttg gatatactgg atagtacaga cagtaagtat ggtgtgagca
    24901 agggtgtatt aggagagaga atgaatgaaa caaatccaca ttttttatgg gctaaaaaaa
    24961 cattgattct atctaaaata tatggtgtat taaataaagg agtagactat gaagaattgc
    25021 ttaaatttta attgtgagat tgacattatt gataatccat tgaatttaga actaaatgat
    25081 tttttagacg taggaataag aaataatagc aaaagacgtt ttttgtttat ctcaaagaaa
    25141 ctcggtaaac atttagcatg taagccaagt gagatggata atttgggaaa attaatggct
    25201 acaatttata atgaaaaaaa taaggaagaa tcaaatggta ctgttatagc ttttgctgaa
    25261 actggtacag ctgttgggca tagttttttt gattacttat gtggagatta tgaatttatt
    25321 catactacta gagagcagtt tgacgagtta gaaaatctgg aatttttaga ggaacattcc
    25381 catgcaacag accagaattt atactttggt atgcttaaca actttaaatt tggagatgag
    25441 ataatattgg ttgatgatga gattaccaca gccaatacat gcatgaatat aattaggaaa
    25501 attcaaagca tttatcctaa aaagaaatac actatatgct caatactcaa ttgggtaagt
    25561 gatgaaaatt taagtaaagt tactcgttta gaaagagagc tagattgtaa gatagatttt
    25621 gtatacttat ttaaaggaaa ctttaaattt tatatagatg aagatattat ttcaaattac
    25681 aacgataatt atagtattac taaattagag actatttcaa gtgataaagt aaatttagta
    25741 gtaaatcata tttatgttga tttagaagat tatattggaa ataagaaata tgtaaaatat
    25801 acaggaagat ttggaattaa tagaagagaa caatttagat taaaagaaat cgttaagaga
    25861 gaaagtaaaa aaataactat ggccagtaaa gaatctttaa aaaatgaaaa agaaaagatt
    25921 ctatttttag gtactgaaga atttatgtat atacctatgc tgtttgcaaa agaaaaagaa
    25981 aatcaatatg atatatacta tcattcaaca acaagaagtc caattattaa tattgataag
    26041 aataattatc ctattaaaag taaatttatg ctaaagagtt tttataatat agatattcaa
    26101 aattatattt acaatataga taaacataat ttttctaagt gttatttatt tgtagagctg
    26161 aataaaagtg aaaattctta tctagaattt attgatataa ttaaaaaaac aagtataaaa
    26221 gaattaacta tagtatgttg tagctaaagt gttttaacag gataaaatat atcacgattt
    26281 taagatagga gttgagtcat atgagagatt ttagcacgta ttctaaagat gatgttattt
    26341 ttttattaaa agatatatca aatttaattg aagaagaagg aaataaagaa agagaattaa
    26401 aaatacaaaa tggtagacat tattcagaaa tgataccaat agagtatgaa gttagtgaag
    26461 attatctgaa tttatatcat gagaaactaa gagaaaataa agataagctt gcattttcta
    26521 taggagttat gtgtgaaaaa ataattaaaa aaaatggaaa tgatgtagta ctagtttcac
    26581 ttgctagagc aggaacacct attggtattt tggcaaaaag atatataaga agcaagtata
    26641 atgtaagttt acctcactat acaatctcta taataagaga taagggaata gatatgaatg
    26701 caattgaata tatagtaaag aatcatccaa gttcaaaaat tcaattttta gatggatgga
    26761 ctggtaaggg aactatatca aaagaacttg aaaaagcatg tgatgaactt aatgttaaat
    26821 ttaaaaaaca ttttgactca acacttgctg tattagctga ccctgctgga tattcaggac
    26881 tttatggaat tagagaagat ttcttaatac caagtgcatg tttaaattca accgtttctg
    26941 gtttagtaag tagaactgta ctaagagagg atttaattgg taaaaatgac tttcatggag
    27001 ctaagtttta tagacattta aaagataaag atgaatctat gaactatatc gaaactatag
    27061 aagaatgttt taaaaatcaa tttaagaata tatctgatga agttgaaaac tgggaaagtg
    27121 acattataac aagagatgga tactttgatg ttttaaatat aaaagaaaag tataacataa
    27181 cagatattaa ctttatcaaa ccaggtgtag gggaaacgac aagggtttta cttagaagag
    27241 ttccgtataa gattcttgtt aaagacttaa atgataaatc tttagaccat atattcatat
    27301 tagctaagga gaaaaatgtt gaagttgaac aaatggattt aaaagcctat aaatgttgtg
    27361 gaataataaa aaatatgaaa gatatttagg aaatatatta gacaggagaa tattgaatga
    27421 ttgttttttc agatttagac aggagtatca tttactccaa taaattttta aatgctgata
    27481 gtaaatatgc taatatagaa atttataggg aaaaagaaat atcttatata tctttagata
    27541 ctataaattt aataaagcaa atacaatatt atggtatgtt tatacctaca actactagaa
    27601 cagtggagca atttaagcgt atagaattta ataaatatgg gatttatttt ccttggagta
    27661 taacttcaaa tggaggagtt atacttaaag ataatgaaat attgaaatca tggagtgaaa
    27721 aaatagataa actaaaatct gattatgagc ccattgaaag tatgattcat aaatttaaag
    27781 actatttgaa tgtagatgga ataactaatt ttaaagttgc agaagataca tttttttata
    27841 tagttgttga tttatcaaga tttaatttgg attcaatcaa agaatataca aatatattgg
    27901 aatcaaaaaa ttggaagttt tatgtgagtg gcagaaaaat atattttata ccaaaagaaa
    27961 tttcaaaaga aaatgctata aaatacttga ctaaagaatt aggaatagaa tatttttatg
    28021 cagttggaga ttctattatg gactatggta tgcttaatat ctcaaataaa tcctatgtat
    28081 tgaagcatgg tgatataaat aaaaatgaaa tagaaaattc atttatatca agttctttca
    28141 atggaatgag tggaactgaa gagatactat ctaacatttt agacgagaac tgcctactta
    28201 acatataatg actgatatat aaataataaa ctagaaaaat ctgaaataaa ttatagtaaa
    28261 gtttatcata ctaatttatt tcagattttt atcaatttat atttaagtaa gaactcaaca
    28321 tgttaaaatg aaggtggagt cattgcccag actgagatac atacctcatc atcataattt
    28381 tcatacacat gtggtatagt actgttaaaa taaaaactat ctccttcctc caatagatat
    28441 tccttatttc caagtgttat cttcatttta ccttttatta tatagccaca ttcttctcct
    28501 tcgtgtgtca caaattcact gtttttttgt gtatgaccat ctagcgtaac aagtataaat
    28561 tctatttttt tcccagataa attaggaaca agaagttcat aaaattttgt agaatcatta
    28621 gttactattt tttttcgatt atttttcttt actactatat cagagtcttc tcttccaatc
    28681 tcttcaaaaa aataacctat atttatatca agagcttttg atattttcca cattgctaca
    28741 atagatggaa caaccatatt acgctcaatt tgacttatta agcctgtact taaatctgaa
    28801 ttttttgcta aagtagagat acttatattt ttagattttc taagagatct aattttgctt
    28861 ccaacatcta tattcattag atacaaaccc cctcagacat gattataaca tataatttat
    28921 aaagattaat aaaataaaaa aaaagtttta caatacaagt attttttatg ctatattgaa
    28981 ttttctgaaa agatgcatta taatagtatt aatattcaat atattgaata ttgataacga
    29041 tattttaatt taatgaaatg gaggtaatta agatgaagag ttttgtaagt cctgataata
    29101 tttgggtatt atgggcagtt gtaactggat gggcagcatt tagtatttat ttggaacaaa
    29161 agtacaattg ggcatcaaaa gtgtcgggag caataatagc tcttgtagga gcaatgttat
    29221 tatcaaatct aaatattata ccagtagagt ctgttgtata tgaccaagta tggggatatg
    29281 ttgttccttt agccatagct ttattgttat atcaatgtaa cattaaaaag atatggaaag
    29341 aaagtggaag attgctcatt atatttcttg taggttctgt aggaactgta cttggagcta
    29401 tgattggatt tttagcatta aaaaatgtag taccagattt aaatattgtt gcagctatga
    29461 tgacaggttc ttatataggt ggaaatgtaa actttgctgc tatgtcaggg gcgtttgatg
    29521 cgccaggaga attagtatca gcaacagttg tagcagataa tcttttaatg gcattatatt
    29581 tctttgtctt aatagctata ccatcaattg gattttttag aaaacatttt aaacatccac
    29641 atgtagatga aatggaaagt ataggtataa ctgaaggaga aacagtagca gcaaattatt
    29701 ggggaagaaa agaaatatct ttaaaagata tagcaatagc cattggtagc gcttttataa
    29761 ttgttgcagt atctgtagaa ctatcaactt ggtttaaagc tataatacca ttatcaaatc
    29821 cttttttagc aatgttaaat actttatttg gaaatcaata tctaataata actactttga
    29881 ctatgttgtt tgccacattt atgcctaatt tctttggtga tataaaagga gcacaggaat
    29941 tgggtacatt tttaatatat atattctttg ttgtagtagg tgttcctgct tcaataacat
    30001 taataattca aaaatcacca ttactacttt tatactgcgg aataatggta ctaataaaca
    30061 tgctagttac atttatagtt gcaaaaatat ttaagtttag tttagaagaa gctattcttg
    30121 catctaatgc aaatattggt ggtcctacaa cagcagcagc tatggcaata tcaaaaggat
    30181 ggtctaagct agtagggcca atacttatag ttggaacatt tggatacata gtcggtaatt
    30241 attttggtct tttagtagga aatattttga tataatttta cgtgaaaaaa agttgttttt
    30301 tagaaagatt tttatttatt agaaagattt ttatttaatt ggaggttgtt atgattttcg
    30361 atggacattc agatacttgg gcagatgtaa caataagaag gcttaacggg gaaaaagatg
    30421 tatttagaag aatccatctt gataatttta aaagagcaaa tatagaagga gctatttttg
    30481 taatatggat agacccacca tatgataaag agcctgaaaa aagagttaaa caaattataa
    30541 gctctataaa agatgaaatt gaagatatga aagatgttgt aaacatagta aaaaaatatt
    30601 cagatataga taaaggtata agtgaaaaca aaataaatat tttaattggt cttgaaggat
    30661 taagccatat tggaagaaat atagatttac tagattattt ttataaagaa gttggtgcaa
    30721 gacatgcatc attaacttgg aatgaacaga atgaacttgc tacaggatgt ttaggggatg
    30781 aaaatcgtgg tttaactgaa ataggtaaaa aagcagtcaa taaaatggaa aaattgggca
    30841 tgatagtaga tgtgtcacat ttaaatgaaa aatcattttg ggatttaata tctgttgcaa
    30901 gtaagccagt tatagcttct cattctaatg ctaggagttt atgtgatgct aaaagaaatc
    30961 ttacagataa tcaattaaaa gaaatttcaa atacaggtgg attagttgga ataaatagtt
    31021 ttagaggatt tactaatagt aatcctaaga agcaagattt aatacatttg gttgaccata
    31081 tagactatat ggtaaatctt ataggtatag aacatgtatc ttttggtttt gattttagtg
    31141 attacttagg gaaagagact ataggttctt ttactggaaa tgctagtgtg ccaagtgtag
    31201 atggtcttga aagcacacat acagcacaga acatagtagt agagcttgaa aatagaggtt
    31261 ataaaaagaa agatatagag ttaatctcta gtggtaattt ttataggctc tttaaagata
    31321 tactaaaata atataataaa gaacttaaat ttataaaata gtatatttat acaataatat
    31381 ctacatattt aaattggcgt tcataattta ttaaattaaa ttttaatgtt actagaagtt
    31441 tcaattctag taacattttt tatgttaaaa acagatatag atatgtattg acaatgataa
    31501 ttattattga taaactataa aagtgaaaat gataataatt ttcattttaa ttaataaaag
    31561 atttttaagg agggagaatg aagaaaaggt atttagtcat aggaataata attttgtctt
    31621 atttttcttt atttatagga gctgaagata taaatataat gcatatattt gccaaaaatc
    31681 agcataaact tatgatattt atcatgagta gaataccaag attaataagt atattgattg
    31741 ctggtgtagg aatgagcata gcaggtctta taatgcaaca gataagtaag aataaatttg
    31801 tatcacctac aacaggtgct acaatagatg cagcacaatt tgggatagta atatgtatgc
    31861 ttttagtacc aactgcctct atttttacaa agacaataat agcatttgta ttttctcttg
    31921 tagggacttt tacgtttatg aaaataatag ggaagttaca atttaaaaat ataatctttg
    31981 taccattagt aggtataatg tttggaaata taataggttc tatgacggat tttatcgcgt
    32041 ataaatacga tttgagtcaa aatgttagtt cttggatgca aggtgacttt tctatgatac
    32101 ttaaaggaaa ttatgagata ttatatatca caatacccct tataatatta gcatatattt
    32161 atgcaaataa atttactgtt gttggtatgg gtatggattt tgcgacaaac ttaggtctta
    32221 gttacaaaag aattgtcaat ataggtttga taatagtagc acttgttaca gtatgtgtag
    32281 tcgttacagc tggtaatatc ccttttatag gtctaatagt tcccaatatc gtatccttgt
    32341 atatgggtga taatataaga gaaagtatat ggtatactgg tttacttgga gcaatatttg
    32401 tacttatatg tgatattttt ggaagaatta ttatttatcc atatgaaata tctatagggc
    32461 ttacagttgg agttatagga agtatactat tcctttattt aatattaagg aggaacgtaa
    32521 atgaagctta gtctcaatca aaaaatttac tttgtaagta tattactatt catatcaata
    32581 gcactttttg taatttatgg aatagacatg aatcacttag aatatgcatt atcacaaaga
    32641 ataccaaaaa tatttgctat ggtattaggt ggaggatgta tagcatttac tactgtagtg
    32701 tttcaaacaa ttacaaacaa tcaaatatta acaccaagtg tactaggttt agattcattg
    32761 tatgtaatga ttcaaactat aatagtattc atatttggtt caagcagtag tctgattata
    32821 aatgaaaatt ataattttat tattaatgta gctatgatga ttggagcttc attgttatta
    32881 tataagacat tatttgaaaa aaataaaaat aatattttct ttttaatcct agtaggaatg
    32941 atatttggaa ccttatttaa aagtgcaaca acatttattc aggtaatgat agacccgaat
    33001 gaatttttag ctttacaaac cagtataatg gcaagtttaa acaatataaa cactaatgta
    33061 ttgttaatag catttataat aattattgcc ataatacctt ttatatatga tgaaataaag
    33121 tatttagatg tattgtcgtt aggtaaagaa caagcaatta atttaggtgt agattttgat
    33181 aaagcagtta aaaaaatgat aatattaata gcaattttag tctcaatatc aacagcactt
    33241 attggaccta tgacattttt aggactttta cttgctaata taacaagaga aatttttaaa
    33301 acatataagc atacatactt gatttcgggt tctatgttga tagggatgat tacattgata
    33361 ataggtcaat tttttataca acatgtattt aagtttgata caactttaag tgtagtaata
    33421 aattttatag gaggaattta ctttattcaa ttactattaa agggggcaaa tagatgatag
    33481 agataaaaaa tatatttaaa agatataaga ataaaaatgt tgtagatgat gtctctttta
    33541 gtatagaaaa gggaaagata acatctttta taggaccaaa tggagctgga aaaagtacag
    33601 tactatcaat agttacaaga cttataggag gtgatggtgg agaagtaata atagaaggaa
    33661 aaagcttgac taattatagc aataaagaat tagcaaaaaa aatagctatt cttaaacaat
    33721 ctaacaatat aactttaaag cttacaataa gagaattagt tggatttgga agatttccat
    33781 atagtgaagg taatctaact aaagaggatg aaaattatat tgatgaagca atagaatata
    33841 tgaagttgac tgatatacaa cataagtatt tagatgaatt gagtggaggt caaagacaaa
    33901 gagcttatat agcaatggta atagctcaag atacagagta catattactt gatgaaccac
    33961 tgaacaattt ggatatgaac cattccgtac agatgatgaa ggtacttaga ggtctttgtg
    34021 atgagttaga taagactata gtattagtaa tgcatgatat aaattttgca tcatgttatt
    34081 cagataatat agttgcatta aaaaatggaa aagttaaaaa agtaggtcgt acagatgaga
    34141 tagtaaatga aaaagtttta gaagatattt atgagatgaa ttttaacatt aagaatataa
    34201 atggaaatcg aatctgtatt tatttttaaa atattgtata tggaaataaa cttgctatat
    34261 gattttttat aaagttttta aattaaaata aagattaata ggagagagga aaatattgat
    34321 atgaataaaa aagcagcaat agtagcaaca gtagctatta taggattagt gacagtgttt
    34381 gcattaggtg gaagtaaaaa gaatgaatca aaaacatcag aaaattcaaa taatactatg
    34441 aagataactc ataacttggg agaaacagat gtaaaattaa atcctaaaaa agtagtagta
    34501 tttgattatt cggctttaga tacaatggat gcattaggtg tagctgagaa tttagtagga
    34561 cttccaaaag cgagtttacc agcatcctta gaaaaatata aggatgacaa gtatgcagat
    34621 ttaggaggct taaaagaacc agatttagaa ggtataaagt cggcaaatcc agatttaatt
    34681 ataataaatg gaagacaaga agatttttat gagcaattgt caaaaatagc accaacaata
    34741 agtacaagta aagatgataa gaagtactta gaatctgtta aaaataatat agacaaaata
    34801 gcaaaaatat ttggagtaga agaaaaagca aatcaagaat ttagtaaaat tgaaaagaaa
    34861 atagaaactt tgaataaaaa agtaacagat aaaaatttaa atgctttaac tataatggta
    34921 aatgaaggta atttaagtgt atttggtgaa gaatcaagat ttagtatatt atacaatagt
    34981 tttggatttg aaaataaaga taaaaatata aaagaatcaa gtcatggaca aaatattact
    35041 tttgaatata tagctaaaca aaatccagaa gttatgttcg ttatagatag aggaatagct
    35101 actggcagtg atgtaaaaga aagctcaact gcaaaatctg ttttgaacaa tgatataata
    35161 aaatctatgg atgcatataa gaatgataat ataatatatt tagattcacc aacatggtat
    35221 gtaaatgatg gtggtctaac atctttaaat aaaatgatag atgatgcttc aaaagcggta
    35281 aattaataat ccgatataat caaaatgtat tttttataaa atgattatca aataaactag
    35341 gagtttttaa gaactcctag tttatttttt gcataaaaaa gatatagttt aaacaataat
    35401 attatctata ataagataaa tctattcaaa atctaataaa atatgaagtt atactagaca
    35461 aaaagaataa ctcttaaata taattaagtt atataataat atataattat aatgatataa
    35521 ttttaatagg tggtttgtaa ttaaaaagtt tataaattac attaagagta ataatctata
    35581 agaacttata tattagaaaa aaatttttgt atatatagag gactctaaag atgaactatg
    35641 taaaacaagg tttatatatt ctaatagtat agcaaaattt attgtaaacg catgtatatt
    35701 attagaaaaa atagtttgaa ggtattcaat aaacataaaa aacaatatag gggataaagg
    35761 tgttttatga agagattttt gaggagaatt atcttagttt tatttatttt gttgattttt
    35821 ataagtttta tttctattaa attaattcat aatgttggag attatggaaa attgattaat
    35881 tatgttggga ttgttcgtgg agctagccaa cgtctaacta aactagagat gaatcatcaa
    35941 ccaaatgatg aattaataga atatattgat gaaatcctac aggagttgat tacagggcat
    36001 ggagattatg gtttagtaat cactgattgt aatgaataca atgaggactt acttttatta
    36061 gaaaaaaagt gggaagattt aaatattgaa attaaaaaag taagaatgaa agaacagaat
    36121 aaccagttat taagtataag tgaagagttt ttttctcttg caaatgatac agtgtttaaa
    36181 atagaaaact tttctaaaga aaaaagtaat tacttaatga ctttaataat aattatatct
    36241 attataggta tattagcatg tatcatattg attttacaat atagtaaaaa aatggttaga
    36301 ctggaaaaat taaatgtaga tttaaaaaat attgcatata aagatgaact aacaggagta
    36361 aatactatag aaaaatttaa attggatgca aatcaaaata tttgtataca taaggataag
    36421 aaatttgctg tattctatat tgattttgaa aactttaaat acattaatga tatatttgga
    36481 tatgattatg gtgacatgat actgaaaaga tatgctaatc ttatgatgaa tgacataggg
    36541 aaatatgaaa tatttgcaag agaaattgca gatagatttg ttgcgttaag atgctatgta
    36601 gataaggaag atttagtggt aagacaacga gatgtagaca atgaactaat taatataaca
    36661 aatgaaatta aaaataaaca tagtattact gttgttagtg gaatttgttg tattgaagat
    36721 gtaaatgaaa aattaagtat agatggttta ataaatagag caaattttgc acaaaagact
    36781 gttaagaata aaccaggtac taattatgct ttttataatg acagtattcg taaaaaaatg
    36841 attgaagaaa atactatcaa gagtagaata catgaagcta ttgaaaaaag agaatttata
    36901 gtttatttac agcctaaagt taatttacat agtcaaaaaa taaattgtgc agaagcttta
    36961 gttcgttggc ttactccaga taaaggtatt atatcgccag caatatttat tccagtactt
    37021 gagaagaatt tttttattgc cttagtagat aagtatgttt ttgaggaggt ttgtaaatgg
    37081 attagaaaga ggttagatga aaataaacct tttgttcaga tatcagttaa tgtttcaaga
    37141 atacaatttt ataacactaa atttgtagaa acttattcca atatacaaaa taaatacagg
    37201 atacctaaaa atactataga aattgaattt acagagagtg ttgcttttga gaatcaaaaa
    37261 catcttttgg aaattataca tgatttgcat gaaaatggat ttacttgttc tttagatgat
    37321 tttggaaaag gttattcgtc tttaagtgtt ttaaaagatt taccatttga tgttttaaag
    37381 cttgactcta tgtttttcaa ggctagttta gataaagata aagagaaaat agtaataaaa
    37441 aatattgtac atatgttaaa agaacttaat atcacaactg ttgctgaagg cattgaatgc
    37501 aaggaacaag ttgaatttct tagggatatt gggtgtgatt tagttcaggg atttgtattt
    37561 tataaaccaa tgccaatatt agaatttgaa aaaatattgg ataaagagtt tgtttataat
    37621 agctaaaatg tactttataa aatatgaact aattaagtaa aattattttg tactgaataa
    37681 atttttactt tatttacaga ataatgatta tttacagaaa agcgcgaaaa gtgtattcct
    37741 ttaagtgtgg gatggatagc acaaataggg gagaaaaaat attggccata taagaatgca
    37801 taataatata aatatttgaa aggtcagcat catataaaaa ttaaaaagaa aataaataat
    37861 ttttctataa aaaagagact atgagaaaat ttactcatag tctcctaaat aatgtattta
    37921 ttttcttcct gcaacccatt ttaatcccca atgaaattca gtatccattt ctctatgacc
    37981 tttgaagtat ttaactactt tttcaacact gaatgtctca tcatttacat tttctatcaa
    38041 tgctattgaa cacatattat agccattttt atgttcatca agtttgacaa ctaagtctga
    38101 atcttgtttt tgtttgattg ttacaattcc atcagcttca gaccagttag ctacaccttc
    38161 gtatataaaa gcataaataa gtattctttt tatatctttt attttattac catttattct
    38221 taaattttct ccttgtgtat tacttcctgt tctgtcatct ccatctaatt gagcaaaagg
    38281 tggattgtct aaactaccaa aggcatttcc taatgcttga acagcacctt ttacaccatt
    38341 tttcatctca aataggcaac ccaaatctaa atctatatta ctgcttctca aagagccaaa
    38401 aaaacccttt ttttgtactt tttgattcca atttaaatta actaagattt cacctaaatc
    38461 gctattttcc ttttttgtaa ggtttatttt ttgtcccttt tttaattcta tagccatagt
    38521 aatcttcctc cacaaacata gatttattta aatggtagca cttaataagt caatattcaa
    38581 caagattaga ataataatat taaaattata ctaaatatac taaaaagtag gaatcacaat
    38641 acctttgtat ttttcttcaa ttaagcttct tgctttatct gatgtaagaa catcttgtag
    38701 aactttaatc ttttcactgt ctttatcttc agttctaaat gctaaaagat ttgcatactc
    38761 gtcatttata ggagctgtat aaattccgtt tttcttggca tcaagaccag caggtacagc
    38821 ataagtagta tctataaatg cagcagtcac atctggaaga gaagctggaa tttgagcaat
    38881 atctaactct ttgaattgta ttccctttgg attttctatt atgtccttag gactaactaa
    38941 tccatcccct ttaggtaacg ttaaaagtcc aatactttca aggtatctaa ggttcttaga
    39001 acaagaagat gggttattgc ttattgcaat tgtatctcct tttttaaatt catcaacaga
    39061 ttttatctta taagagtaaa gtattgctgg gcatacatat agttttttac cagccattat
    39121 tttgtaacct ttggccttaa cagcttcttt tagataaggt tcatgttgaa atagatttgc
    39181 atcaatttca ccattattta aagcttcgtt tggaagtatg taatcatcaa agtttttaac
    39241 ttctaaagta tatccttttt ctttaataag tggttttaat tcttctaata actctcctcc
    39301 tggaactaaa gtagcaccaa caacaatttt tttatcatct ttagctttag aacatccaac
    39361 cacagctaaa gttaatacta gacataataa caaacataat aattttttga atttcatata
    39421 aattccctcc tgaatataat tgattagtta aaaataaaat accattcttt atcacactgc
    39481 aaaataaaaa taagcctgag tttaaactca ggctttaaaa gctaatttag actcatcttt
    39541 cagtataata ctgcaggatt tagcaccaat gtatataaaa atatactggt tgctgggttt
    39601 catagggcca gtcccttcac cactctggat aagaagtatc aatttttaat tatgttataa
    39661 atattatcat gattttttac gtctgtaaac ataattttat aaatatttta aaatctttaa
    39721 tgtattttat ttaacaccta aaattccaga aactagaata tcagtatcag cacctaagaa
    39781 atagtcattt atttcaatag aatccagagt atttctcaaa gcattttctt catgccttat
    39841 accaataagt ttattttcta caaatgcaac atcacatttt ccaaaaaaat ctccaaaaaa
    39901 ttttatacta gttattatgc ctttatcaac atttaaatta aactcaacat ttccaccaga
    39961 atattttaat tcatttgaaa gagtatattt tggtgaatta ccaaaattcc aatcccaagt
    40021 ttcgtatttt gatttagtaa gcttttctat ttgttttata tcatgctcac tcaaacaata
    40081 attagtatta tcagtatttg ttttagaaag ataatccatt atagcatctt taaattctaa
    40141 tatatccatt tttgaatgta aatgttcact tatattggtt acacgagatt ttacagattt
    40201 tattcctttt ccttcaaatt ttataggttt aacctttaat gcttttgaga ggtcatttat
    40261 ttcagatgaa aataaaagag tcccatgatg cattactttg tttttgtagt tgtattgagc
    40321 atttccagaa aatttcttgc catctataag aaggtcattt cttccagaaa attcggcatt
    40381 gacatctagt gttttaagta aatctattat gggctgagtg aatcttctga aatcactaaa
    40441 attattattg ttacaagcta taaatgtaaa atttatattt cccaaatcat gaaatacagc
    40501 tccaccacca gactgtctcc taacgacagg tatagaatat tcttttatat attctaaatt
    40561 tatttcagaa agtgtgtttt ggttttttcc aacaattata gaaggttcat tcctccataa
    40621 aataaataag tcttcatcaa aattttttag aagatattct tccattgcta aattaaaata
    40681 agggtttgtt ttttcattat aaattaataa cattaaagta gttcctccat agaattgata
    40741 aaatttttat tatgaataca attaatttta taattcgaca ataatataaa aactccttta
    40801 aattagaaat tttaaaaact accttgcaaa gtttaaataa ataatatata ctcaaaatat
    40861 gtttaataaa agtgaataga agggtagagg cgcaataatc tatcagtact aataaggagt
    40921 taagcacaga gatttattag gaaaggagat attgccgaag ttttataatc gatgctttaa
    40981 gattatattg ctgggggtac atagaaaata tgtacaactg tcacaggttt atttgtggtg
    41041 agctatcatt taaggaatta tattatattt atttttacta ttgttgatat attgtaatgt
    41101 ttaagccttg agtgtttacc actcaaggct tttttagttt tattgtaaca taataccctg
    41161 tacagttcac aaaattaaaa ggagagggag atttatatga ggaacaaaaa aattaatatt
    41221 atttttctga cgacaatcat gttcataatg tcaacagtaa tggtttttgc agaagaagat
    41281 atagacacta ttgcactagc caatgcagaa aaatttggga ttttaacttt aataccacca
    41341 ttagttgcta taatacttgc atttataact aaaaacgtaa taatttcttt acttataggt
    41401 attctttctg gtagttttat aattaaagct agtggtatta atgtttttgc gacatttata
    41461 caggcatttt tagatttagt agacagagct ttagtatctt tagcagaccc ttggaatgca
    41521 gggataatac tacaggtttt ggcaattgga ggagtaataa atcttgttgc taaaatggga
    41581 ggagctaaag ctatagctga agcacttgct aaaagagcaa agtcagcaaa agggacacag
    41641 cttataacat ggtttttggg gcttttagta ttctttgatg attatgccaa ttcactaata
    41701 gtaggtccta tgatgagacc tgttgcagat aaaatgaaaa tatcgagaga aaagctagca
    41761 tttataatag atgccacagc agcaccagtt gctggtttag ctataatatc tacatggata
    41821 ggtcttgagg ttggtttaat acatgatgct tttgaaagta taagtataga tgtagatgca
    41881 tttggtatat ttttaaatac aataccattt agattttaca atatattaat attagctttc
    41941 attgtaatat cagcattatt attaaaagaa tttggtccaa tgagaaaagc tgagataaaa
    42001 tctagaagta gaaaaattag tatagacctt gatgaaggcg tagaagagtt ggatgattta
    42061 gctccaaaaa atggagtaaa attgagtgta tggaatgcta taatcccaat aggaacattg
    42121 ataatagttg cattagcatc attttattat agtggatata catctataat gggaggagac
    42181 gataaggctc tgatacaact atttacaaat tctccatatt cttttgaagc aataaaagaa
    42241 gcatttagtg catctgatgc atctagagca ttattccagt ctgcacttgt tgcaagttta
    42301 gttgctatta taatggctgt agtaaaaaag atttttacaa tatcagaagc aattgatgtt
    42361 tggatagatg gaatgaaaag tttagtaatc actggtgtaa tattaatact tgcatggtca
    42421 ttaagttcag taataaaaga gttaggtaca gctaaatttt taatacacct attatcaggt
    42481 tcactaccac cattcttatt accaagttta atatttggtt taggagcaat aatatctttt
    42541 gctactggaa cagcttatgg aacaatgggt atacttatgc cacttgcaat tccattagca
    42601 tactcattaa atcctgatat gtcttatgta atagtaagta ctagtgcagt tttaacaggt
    42661 gcaatatttg gagaccattg ttctccaatt tcagatacaa caatactttc ttcaatggga
    42721 gctggctgta atcatataga ccatgttaac actcaaatgc catatgctat atttacagca
    42781 gtaatcacta ttgtatttgg gtatatacca gctggacttg gattgccaat atatatagta
    42841 ttaccagtgg caatagctgc tatatttgta ggtattcaaa taattggtaa gaaagttgat
    42901 gaagcggaaa tagaacttgt agaataaaga tataaataag tttcaccttt tattatcact
    42961 attttgttag tttttagata attttaaaaa gttattgaaa ataatggcga aatatagtaa
    43021 aataaaagag tgataagcgg atgtggcgga attggcagac gcactagact taggat
//
LOCUS       DAEPXW010000271        15199 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.guided.094, whole genome shotgun sequence.
ACCESSION   DAEPXW010000271 DAEPXW010000000
VERSION     DAEPXW010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.guided.094"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="KRM55_003835"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="KRM55_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH1595976.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="KRM55_003836"
     CDS             1575..2258
                     /locus_tag="KRM55_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1595977.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="KRM55_003837"
     CDS             2255..4915
                     /locus_tag="KRM55_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595978.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="KRM55_003838"
     CDS             complement(5096..6277)
                     /locus_tag="KRM55_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595979.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="KRM55_003839"
     CDS             complement(6277..6939)
                     /locus_tag="KRM55_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595980.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7071..7709)
                     /locus_tag="KRM55_003840"
     CDS             complement(7071..7709)
                     /locus_tag="KRM55_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595981.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            7888..8493
                     /locus_tag="KRM55_003841"
     CDS             7888..8493
                     /locus_tag="KRM55_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1595982.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            8997..9746
                     /locus_tag="KRM55_003842"
     CDS             8997..9746
                     /locus_tag="KRM55_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1595983.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            9743..10507
                     /locus_tag="KRM55_003843"
     CDS             9743..10507
                     /locus_tag="KRM55_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1595984.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            10606..11427
                     /locus_tag="KRM55_003844"
     CDS             10606..11427
                     /locus_tag="KRM55_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1595985.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            11441..13105
                     /locus_tag="KRM55_003845"
     CDS             11441..13105
                     /locus_tag="KRM55_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBH1595986.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDESYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            13110..14984
                     /locus_tag="KRM55_003846"
     CDS             13110..14984
                     /locus_tag="KRM55_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1595987.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
BASE COUNT         5711 a         1749 c         2522 g         5217 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacctaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaatga taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtattacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaaggc gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atataaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac ccttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataag
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggatatag aatcttaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctatagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggc tgactgaaaa agatgcatca aaagaacttg cgaaaaatgg
     3901 aggatttaaa agtatagttt catctaaaaa atactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttataa tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtacagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtagagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaagtaa
     5701 ttggagtctt aagttgatga gcaatatctg caagattatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatat aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ctgtcctcca ttctatatcc
     6301 tatgcctctt aacgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggactgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca tcatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttt atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacataaatt tattaaaaga aaaaaacttt
     7321 tctttaaaca gcatatcagt atccgatttt tcagagttta caataccaat cattcccata
     7381 aggcataata gagaaggttc tacagagtaa aatttatgaa aagcaaagta tgaaagtttt
     7441 attttttcaa accctgtttt gccttttgca ctttctattt taacattatc ccaaagtctt
     7501 ttatatcctc ttaagacaac agcaaagaat aaatcttctt tacatgaaaa gtacttgtat
     7561 atggtgcgtt tagtatattc aacttctttt gctaattcat tcatagttgt attatcaaat
     7621 ccattaagac aaaataattt ttctgcctta tcaataatct cattttctct ttgtattttt
     7681 tctttatctc tttttgataa ttctgacata taaattattc ctttctattg ataaaaaagt
     7741 atactgatgg tatacttatg taaatataat acttgtatac ctatagtata ctttaataaa
     7801 aaataaaatt aatatcaagt attataacta tttataactt tattaattaa ttatataggt
     7861 aaaataccaa ataaggggaa tttatttatg aagataaaag aaaatgtatt aatgttagat
     7921 agtactcgtg gctcaaattg ttttattgtg tttgataaag aaattattct tatagacaca
     7981 ggtcttcctt ttatggggaa aaatataatt aaagaattaa aaacacttgg cattaaactt
     8041 acagatatta agcatatttt attaactcat catgatgttg accatatatc taatattaaa
     8101 ttattgaaag aaaaaacagg agcaaaagta tgggctcatg tagaggatat accttttatt
     8161 ataggagaga aggatagacc tgggtttaag aagtttattg gaaaggcaat ttccagaagg
     8221 ctcattaagg atgttgaacc ttatggagag aatatgcaga ttgggaatat aaaaattatc
     8281 catactcctg gtcatactcc agggcatgtc tgcatgattt ttgaagctgt attatttgca
     8341 ggtgatttag tcaaaaataa gaatggaaat atagttcctt atcctaatcc atggaattgg
     8401 gattataaaa agatggtgaa atctataaga gaattggata atttaaaata tgaatggata
     8461 tgtatgtctc atggaactcc ttgtattaaa taataaaaat taacatggat taatagaggc
     8521 atagttgctt gtatgtatga taataattta cagcttcttt ttaatatatc atgtatattt
     8581 gtagctgtaa gcatatttat aacaatactt acaattttgt attttaacat ctataataat
     8641 agttttagct ttgttaacta tgaaatttac ttaaagaagt aaatattcaa gtaatagtaa
     8701 ttattaaata agataaaaag taaatggcag atgaattaaa gtaatttcta ccatggaaaa
     8761 tacttttgag ttagaaaaaa ctatatttta gagtatgaag agatgaagct tccgaagaaa
     8821 gcaatatcta aagtacatgt tcgaaaggat aagtactttt tggtgcctgc ttttagcagg
     8881 ttatttttat tttaataaaa ataaaatcaa atgattattt tatccttatt atttaaaact
     8941 cttccctaga aaaagcaact aatgtatatt aaaataatat ttagggagtg gaaaaaatga
     9001 gattagaatc gttagttaac caaaattatg ataatttaaa tgaaaatgat aaaattatta
     9061 ttaaacaaat attgatttgt caaagagaat accgtaattt ttcgtgtgaa aaaattgcaa
     9121 atgaatgtaa tgtttctaga gctactttat taaggctttg tagaaaaatt ggattagatt
     9181 cattctctga tttaaagtat ttacttaaaa ataatcaact agaatttgtt aataatgata
     9241 ataattttca tgatgtttgc gagaattatc gactattaat gaatgaatta caaaaaatat
     9301 catttcaaga tatttgtaaa ataatatatg atgcagaaac aatttatatt tatgggacag
     9361 gtaatgaaca gaaaagttta gctcaagaaa taaagagaat atttctttca gtaggtaaat
     9421 gtgttattga cttatttgat ataggtgaaa ttgaatttat gagagaatca tttcaaaaaa
     9481 atgatttatt tattatcatt tctttgtctg gagaaacaaa agcaggaatt gaaattgcaa
     9541 aatttatcaa caatcatata catacgattt ctttaactag gcttgataat aatacaattg
     9601 caacactttg tgagtataat ctgtatgttg aaacgcaaaa acttgataca ttacaagcta
     9661 tatcttatga agtcgtagga gcattttatg ctctattaga tttgcttcat atgaattaca
     9721 tagagtatag aaggagaaaa gaatgaaaat tgaaggactt ttcaataaat attataattc
     9781 atttacagca aatgataagt atatctgtga gtgtattctt aatcataaag aagattgtat
     9841 taaactttct atagatgaat ttgcagacaa ataccatata tctacaagtg cactttctcg
     9901 ttttgctcaa aaactacaat tacctggata tagtgaatta agagttatta tacgcttaaa
     9961 tgaaacagaa gtagaatata aaaatcaaag taaacaccaa ttaatggatt gttataataa
    10021 ggtgatagat gatatagaga agaaggattg ttcgattatg tttgaaagaa tgaaaaaggc
    10081 aaatcgtata atcgtctttg gagaaggtta ttctcaggaa agagttgcta aagagatgaa
    10141 aaggattttc ttaccaacag ggaaaattat atatgatgtt tatggttatg atatgattca
    10201 ggcacttaat cattttataa aaacagatga tatgattttc tttatttcat tgaatggaga
    10261 tgcatctaca attattgatt ttgctaaaga aatgagaatg aaaggaattt atatggtttc
    10321 tattacaaaa atgataagta atcctttagc aagattatgt gatgaaaacc tgtatattca
    10381 atctatatct atttctgtag ataaacaact ggactacgat gtaacaacac cttattttat
    10441 tttaattgaa ctgctttata ttaaatacaa gatgtattta gaaagtgaac atattccccg
    10501 aaaatgaaaa tttgtgctaa aaatgaacat attttttaaa agatatcaaa atattgatat
    10561 cttttttttt gaatgctatt atgattttga tagtaagaaa ggaagatgaa attgtacaaa
    10621 ttattaatac ttgatataga tggtacgctt agagatgagg tatatggaat cccagaatct
    10681 gcaaagcatg ctatacgttt atgtcaaaag aatcattgca gtgttgttat ttgtactgga
    10741 agaagtatgg gtacaataca agatgatgtt ttatcattag gagttgatgg atatattgca
    10801 ggaggaggta attacattca atatcatggt gaattacttt ataatcaatc ttttaatcaa
    10861 agattgataa aggaagttgt ttgtttatta aaaaagagag aagttgcttt ttcgattgag
    10921 agtcaggaaa aagttttcat gaatcaaaaa gccaaagaaa tatttgaaac aatgaatcag
    10981 ttaaaaggaa ctaattcttg tataaataaa caacatatcc aagaaaaaat aacatatgaa
    11041 aataacattg aagagtataa gtcacaagat atacataaaa tttgtttatg gtcaaatgaa
    11101 aaggtatttg acgaagtgaa agatatacta caagataaaa tggaattagc acagagagat
    11161 atttctagtc agtattatga aattattcaa aaagattttc ataagggcaa agcaattaag
    11221 agattacaag aaagattagg agtaactcaa aaagaaacca tatgttttgg tgatggtcaa
    11281 aatgacattg tcatgtttca agcatcagac gttacaattg caatgaaaaa tagtcatcaa
    11341 caacttaaag atatagcgac atctatatgt gaggacatat tcgataatgg aatttataaa
    11401 gaattaaaaa gaagaaatat catataaaaa ggagtaattt atggaaaaga aatggtggca
    11461 aaaagaaatc gtttatcaaa tttatccaag aagctttcaa gatagtaata atgatggaat
    11521 tggagattta cagggaatta tttctcgttt agattattta aaagatttag gtattacatc
    11581 attgtggtta tgtccaattt ttaaatcacc tatggacgat aatgggtatg atattagtga
    11641 ttatttggat attgcaagtg aatttggaag tatggaagat ttaaaagagt taattaaaga
    11701 aagtaaagat agaggaatca aaattatatt agatttagtt cttaatcata caagtgatga
    11761 acatccttgg tttcaagaag cattaaaaaa tccagaaagt ccttatcatg attattatat
    11821 ttttaaaaaa ggaaacgatt taccaaataa ctggaggtct gtttttggtg gaagtgtttg
    11881 ggaaaaggta gagaatagag acgaatatta ttttcattct tttggtaaaa aacaacctga
    11941 ccttaattgg gaaaatccaa tattaagaag tgaactttac caaatgatta atacctggtc
    12001 tcaaatggga gtggcaggat ttagagttga tgctattaca tttatcaaaa agaatttaag
    12061 ttttcaaagt ttagaaagtg atggtgttga tggtcttgtt aaatgtacaa aaacagttag
    12121 aaatcagcct ggaatagaaa aaatgcttta tgaattaaaa gaaaatacgt ttaaaaaata
    12181 tgattgtatg actgttgctg aagcagcagg tattagctat gaccaactag gtgattttat
    12241 tggagaagat ggtttctttt caatggtctt tgactttaaa catgctgact tagatgttgc
    12301 ttctggtagt gagtggttta aaagaatttc atggacaatt ccagatttaa gaaaatgcat
    12361 tttagatagt caaatgtatg ttcaggaaca tggatgggca gctaatttta ttgaaaatca
    12421 tgaccaacca agagctacaa caaagtatct tttgcaatac gaaaggaatg atgatgcagt
    12481 aaaaatgttg ggagcaatgt atttcttttt aagaggaacc ccatttattt atcagggaca
    12541 ggaattagga atgacaaatt ttaaaagaga taccataaat gattttaatg atttatctag
    12601 cattgaccaa tactatcgtt caatagatga aagttactca gaagaagaag cgttagaatt
    12661 tgtgaattta agaagccgag ataatgcaag aacgccattt ccatgggcag ataaagaaaa
    12721 tgcaggtttt tcagatacaa caccatggtt aaaggttatt gaaaattata aagatattaa
    12781 tgcacagagt cagattaaca attcagagag tattttagaa ttttataaaa agatgataaa
    12841 gttgagacaa gatagtgagt attctgattg tttgatttat ggttcaatag aacctattga
    12901 tatagaaagt gatgatatta ttgcgtatag aaggcaatta gatttggtag ttattgattg
    12961 ttattataat ttttctgata aacctgtaga aataagagta gaagaaaaat atgatattgt
    13021 attccaaaat ttagatgata taaatctatt aaataaaaca gtgcgtttga aaccatttca
    13081 tgcagtatta ttgaaagtga ggtagaaaaa tgaataaata taataaaata gcaaatgagc
    13141 ttattaaaat tattggtgaa gataatatta tttctattac acattgtgcc acaagattaa
    13201 gagtgatggt taaagataga gaaattatta atgataagaa agttgaaaaa gttgatgagg
    13261 ttaaaggggt tttctttact tctggacagt atcaaattat tttaggaaca ggaatagtta
    13321 ataaagttta tgcagaagtt gaaaaaatgg gattaaaaac tttatcaaaa aaagaacaag
    13381 atgaattagt taaaaataat gaaactggat ttaagaaagt tatgagaact ctagcagata
    13441 tatttgttcc tattattcca gttattgcag caacaggatt attcttggga ttaaagggtt
    13501 gtttgtttaa tgataatgta cttggattat ttggaatgtc ttctgcaaat attccattgt
    13561 atattcagac acttgtttcg gttcttacag aaacagcatt tgctttttta ccagcaatta
    13621 ttgtatggtc agcatttaaa gtatttggag gaacacctgt tattggactt gttattggac
    13681 ttatgttagt ttccccaata cttcctaatg catattctgt tgctgaccca tcaaatgaaa
    13741 ttgaagcaat tatggcattt ggatttattc ctattgtagg ttgtcaagga agtgttttaa
    13801 cagctattgt tacagcattt attggagcta atcttgaaaa atggttccgt aaacatatgc
    13861 ctaatgtatt agaccttatt ttcacaccat tttttgttat gctaataaca atgttagtta
    13921 ttttgttagg tgtaggccct ataatgcata caatagaatt aaaaatggtt gatatcatca
    13981 gcttattgat tgatttgcct ttaggaattg gaggatttat tattggattt acatatccat
    14041 tagctgttat tactggctta catcatactt atgtaatgat tgaaacatca ctattagcaa
    14101 atacaggatt taatgccctt attactcttt gtgcaatgta tggatttgcg aatattggaa
    14161 catgtctagc atttatgaaa aaatctaaaa ataatcaagt taaacaaact gcggttggag
    14221 caatgctatc tcaacttttt ggtataagtg agcctgtttt atttgggatt cagcttcgat
    14281 ataatttaaa gcctttgatt attatgtgtg catcttcagg tttaggagca gcaatattat
    14341 caattttaca tattcaatct aattcatatg gattagcagt tttaccttct tatttaatgt
    14401 atatctatga tggatataat ttaatcacat acttattagt atcaatattt gtggttgcat
    14461 tctgctttat tgtaacatgt ttatttggag tgcctaaaga agctataaat gaagatgaag
    14521 acgaagaatt agtgtttaat gaaaataatg aaaactttgt gtctccagct aaggggaaaa
    14581 ttgttgcatt agaaaatgta ccagatgaaa cattttctaa aaaaatgtta ggtgatggtt
    14641 ttgctattga tattatagat ggaaaaattg tttctcctat ttcaggtaaa ttagaaacag
    14701 tattttcaag tggacatgca tttgggatta aaggaactaa tggagaagta ttaattcatg
    14761 ttggaattga tacagttgca ttaaatggag atggctttga tgttgctgtt aaacaaggag
    14821 atatggttaa acagggagat gttcttgtta atgttgattt aaagagaata cacgaattag
    14881 gaaagtctac tttgacaatg gtattgtttc cagatggtaa gaaggtaaat attttggata
    14941 taaacaagga tgtaaaaata ggtcaaagaa tatgtgttga gtagtaggtg atatgtaatg
    15001 actacaaaag aagattatca agagtaattc aatcttttta aagtatcaga aataattcat
    15061 aaactctaaa acaattaaag aggttgtttc aaaatagaga ttgtattgca cccaaattgt
    15121 tgaaatgatg aaaatatatt taacttcata caaaaaatta aatagtggca acaattgagg
    15181 atgtgaggga gagttgcca
//
LOCUS       DAEPXW010000272        12555 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.guided.106, whole genome shotgun sequence.
ACCESSION   DAEPXW010000272 DAEPXW010000000
VERSION     DAEPXW010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12555
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.guided.106"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            <1..468
                     /locus_tag="KRM55_003847"
     CDS             <1..468
                     /locus_tag="KRM55_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1595988.1"
                     /translation="YEVDQQIKEGEQTSNVKATYTVKVHVDADGDMVIIQNPTLAPAI
                     EKSDYEPKTPEADASVDADTVNDATAFLETFFKLYPTATEKELAYYVSGNVIEPIGRD
                     YLYSELVNPIFTKDGDNVKVKVAVKFLDNQTKATQVSQYELVLHKDSNWKIVG"
     gene            complement(515..1072)
                     /locus_tag="KRM55_003848"
     CDS             complement(515..1072)
                     /locus_tag="KRM55_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005946872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1595989.1"
                     /translation="MKTTKEAVIKATSDLADEKGLNNVSLKAVAQKLNIRTPSLYNHI
                     ESLDNLLLEVAHNGMRDMNERMMKIAVGKIGKEAIKLVSIEYLNYMIEHPGVYETIQW
                     AVWHGTEETATIFNNYLSLLTTLIQSCSLNKDKTLEILNMLTGIIHGYTTLQLGNAFS
                     ASDKVRFELAEAIDTLLVGIFQKYK"
     gene            1252..1335
                     /locus_tag="KRM55_003849"
     CDS             1252..1335
                     /locus_tag="KRM55_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBH1595990.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            1460..2197
                     /gene="erm(B)"
                     /locus_tag="KRM55_003850"
     CDS             1460..2197
                     /gene="erm(B)"
                     /locus_tag="KRM55_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBH1595991.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            2343..2627
                     /locus_tag="KRM55_003851"
     CDS             2343..2627
                     /locus_tag="KRM55_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBH1595992.1"
                     /translation="MPTKRSGPLVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFR
                     KKKLTKTNVKELLEGKETLVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            2779..3057
                     /locus_tag="KRM55_003852"
     CDS             2779..3057
                     /locus_tag="KRM55_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1595993.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETEQVTLELEMEEEKSNDFV"
     gene            3438..4328
                     /locus_tag="KRM55_003853"
                     /pseudo
     CDS             3438..4328
                     /locus_tag="KRM55_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
     gene            4399..5094
                     /locus_tag="KRM55_003854"
     CDS             4399..5094
                     /locus_tag="KRM55_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1595994.1"
                     /translation="MCTRFVYNGIDKIVGFNFDIDLSVWDHTVITEENRFYIGIKMPD
                     GLYHSFHGINKNGNVGTLLYVHGNENARYIESEDCITISELTEKFIKAEISFDKALDI
                     VKKKKIIYAPDATMQAMLSDKKGRVLIIEPGIGYRYEQENFSLITNYSILKPDITKPY
                     IVSGDTRYEVAKELLAGYDKDFSVNDAFKVLKSVSQKDLWATRVSFVYSTEKNKVYYV
                     LNNDFSNVFEFQF"
     gene            5140..5364
                     /locus_tag="KRM55_003855"
                     /pseudo
     CDS             5140..5364
                     /locus_tag="KRM55_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5410..6702)
                     /locus_tag="KRM55_003856"
     CDS             complement(5410..6702)
                     /locus_tag="KRM55_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1595995.1"
                     /translation="MLNNLYRKLHILFASSVMLIITLVISFVVANTVHTEKINESTLF
                     QRLTTLLIYQVESASSDMDKALKTYEESYHIFSLITDTRGNTIYQSDFPFPTSADNLL
                     HDVEKQISTQPLSQIENSTTSQGGFLEIRGTHHDTYFVIPATIRTANDTVYHATFLYQ
                     TASLTDILQKTLPIYLLIWFLACIVVIVLTRYLLKKSFAPTERILQSQKDFVATASHE
                     LKSPLAVMISNTDMLLDNVSLNEQAKQAVQTIDFECMRLSRLVKDMLLLASSDAKTWT
                     LHKSTINVDTLLITLYETYEPVCMKQNLELKLHLSEESYPAMFTDKDRLFQILCVFMD
                     NAIQHSKNNSLIEIEVIATEKNIAFSVVDHGQGISDEDKQYIFDRFYSGDKSHTNKSN
                     FGLGLSIAKELTQMLNGIIIINDTAGGGATFTVKFPLK"
     gene            complement(6696..7382)
                     /locus_tag="KRM55_003857"
     CDS             complement(6696..7382)
                     /locus_tag="KRM55_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1595996.1"
                     /translation="MKILLLEDDLELCKNIKISLEKENYMVDCCNDGETAMLYALNTD
                     YAYDLAIVDRMLPIIDGLTIIKSMRKKGISIPILIITAMSTLDNRVEGLDGGADDYLV
                     KPFHIKELLARVRALTRRPANIQLSSKLEYGDLTFDKDSRTLSTPVNSLLLTSKETEL
                     TFVFMQNPETLFSREQLILKIWGSSSEVETGNVDSYISFLRKRLKELKSSCKITTVYG
                     AGYKLEKETC"
     gene            7576..8070
                     /locus_tag="KRM55_003858"
     CDS             7576..8070
                     /locus_tag="KRM55_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
                     /protein_id="HBH1595997.1"
                     /translation="MKKTNISKFVAVGLCICALTGCGASPDEKPDMSNPIVNSNTNEE
                     NANGSSENKENDILESANLIGSVLEFTDNGCSVSQAKEIEGGAGIKSEAPGLENKDNA
                     VSVTYNPDCEFVIATVNAQSGVTNVTTGSISDVKKQSEVYLYGEFADTLHFNATKVVI
                     ARWE"
     gene            8082..9305
                     /locus_tag="KRM55_003859"
     CDS             8082..9305
                     /locus_tag="KRM55_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595998.1"
                     /translation="MKFYQLGFRYLQRKKGKTILLLIVLILVNSMILGTSMILRTTNE
                     SKQAMQEKTNSKIVAEITSKDSKITENEVNKIETLEDVSAINRIGRQDVFPASFAPVT
                     LNTSTNEENLKIALLSYDDLEKDSPFSEMQYRLASGDYIKREKKGAVINANLANQNEL
                     KVGDTIELSTENGTKVSVQIIGIFMSAGNAEKDQPSETTAVNRIENQIFIDNSTYKEL
                     FKEAEFEKICIYSKRPEKLDVLETSLQKIFGNDVALSTSDTLYQQMSAPLEQISKVAN
                     LMLVLTLVTGTVVVSLLLCMWMRTRQKEVAIFMSLGKTKSEIFLQTLLEAGSVFTLSV
                     LGATAIGKLFSGVLQNVITGSETVTENLKVVLQIQDIGMLFLLGGAVILVALCCSILP
                     ILRANPKDILAKMEG"
     gene            9309..10754
                     /locus_tag="KRM55_003860"
     CDS             9309..10754
                     /locus_tag="KRM55_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1595999.1"
                     /translation="MNFFGLARRSVFRKPVKSILLLLIVFAISTLLLAGVASKNASIE
                     VQDKTRQAIGAGFLLERNAEYRTKRVREYSEKIGNDKEGSFGGYHQEKEIINGVETWT
                     GWTTNEFESLDIKDIEKLAKAKGIADYNITTVTTPVNPVNFKRIEDKDVDQNADVGGV
                     SLIGNKDMKLDRNVLSGNLHIKEGRMITPEDKDMCVISEELAKQNNLKIGDKISFNDY
                     HDTENSKVSEAEIVGIYQVDQKMSPLMQGDTYRSENVIFTDLRFPEKAEGETSPLYER
                     AYFKVEDVEAYDEVKENLQKVDINWEQYDLIDNNGNSETMSSNFNDLAKVSEMMILVI
                     SVASFVILVLVFLFWLKNRVQEVGIFLSLGVPKFRIIGQIWSEAIMITVLSLMLSFAV
                     APAVSKVTANYLVSQQVQQMQEEEKNNEGKVSTEYVAPKQDVQSISVEVTPEMYLLDG
                     VSVLVLITASVLVSGIVILKRNPKDILSEMS"
     gene            10768..11403
                     /locus_tag="KRM55_003861"
     CDS             10768..11403
                     /locus_tag="KRM55_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1596000.1"
                     /translation="MLEVKNVSYAYKTKKDKTILNNVSATFEEGIFYTIIGPSGAGKT
                     TLLSLLAGLDTAVKGTVLCNGEDITKKGLNYHRKHNISLVFQNYNLIDYLTTVENVKL
                     GGSGNAEKLLEEVGIGKEYWQRNVLQLSGGQQQRVAIARALASDAHVLLADEPTGNLD
                     ETTADEIIALLKKTAHELGKCVVVVTHSKHLAEEADEILEIKNGAISFLSE"
     gene            11678..12118
                     /locus_tag="KRM55_003862"
     CDS             11678..12118
                     /locus_tag="KRM55_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1596001.1"
                     /translation="MKPSELQEKTCHQFDCAIKTVIRHRAIDFYRAIRRSEKKEMPFA
                     EIMDDLLNSIGTEDTYSTDYVAVFEVCGEKVSIEDEQLARALKAIEERKRNIVLQYFF
                     IGDTDTYIGKMLDCSRANVTKCRIQALDKLKQLIEEEKEKCQKS"
     gene            12103..12336
                     /locus_tag="KRM55_003863"
     CDS             12103..12336
                     /locus_tag="KRM55_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1596002.1"
                     /translation="MPKELTPTFTVISKACDGDETAISKILEFYDPFINQCCMRPFYD
                     DNNNLRLAVDLEMKGFIKEAIIRKILNFDIKRF"
BASE COUNT         4373 a         2022 c         2450 g         3710 t
ORIGIN      
        1 tacgaagtag atcagcagat aaaagaggga gaacagacaa gcaatgtgaa agcgacttat
       61 actgtaaaag tccatgtaga cgctgacggg gatatggtaa tcattcagaa ccctactctt
      121 gcaccagcaa tcgaaaaatc agactatgag cctaagacac cagaagcaga cgcaagcgtg
      181 gacgctgata cggtaaatga cgctaccgca tttctggaaa cattctttaa gctctatcca
      241 acagccacag aaaaagagct tgcttactat gtatctggaa atgtgattga gcctatcggc
      301 agggactacc tttattctga actggtaaac cctatcttta caaaggacgg ggataatgtg
      361 aaagttaaag tagctgtaaa attccttgat aatcagacaa aggcgacaca agtatcacag
      421 tatgagcttg tgctacataa ggatagcaac tggaagattg taggataaaa gaaaaaggct
      481 tgcagttctg tattgatttg caagcctaaa tatattattt atacttctgg aaaatcccga
      541 ctaataaagt atctatcgct tcagctaatt caaatctaac tttatctgag gcagaaaaag
      601 cgtttcctaa ttgcaaagtt gtataaccgt gaattattcc agtaagcata tttaatattt
      661 caagtgtttt gtctttgtta agactgcacg attggataag agtagttaat aatgaaagat
      721 agttgttaaa aatggttgct gtttcctctg ttccgtgcca cacagcccat tgaattgttt
      781 cataaactcc ggggtgttca atcatatagt ttaggtattc gatagaaact aacttaattg
      841 cttctttccc tatttttcca acggcaattt tcatcattct ttcattcatg tcacgcatac
      901 cattatgagc aacttctaaa agaagattat ctaaactttc tatgtgatta tataaagatg
      961 gtgtacgaat gtttaatttt tgagcaacag cttttaacga aacgttattt aatccttttt
     1021 catctgctaa gtctgatgtt gcttttatta ctgcttcttt agtggttttc atagttatgc
     1081 acctcattca aaatatcata caaacacaat tctagctaat tgaattagtg tagtcaataa
     1141 cacaattaga aaattatgat tatttattga ctttcttaaa attttgtgta taataggaat
     1201 tgaagttaaa ttagatgcta aaaatttgta attaagaagg agggattcgt catgttggta
     1261 ttccaaatgc gtaatgtaga taaaacatct actgttttga aacagactaa aaacagtgat
     1321 tacgcagata aataaatacg ttagattaat tcctaccagt gactaatctt atgacttttt
     1381 aaacagataa ctaaaattac aaacaaatcg tttaacttct gtatttattt acagatgtaa
     1441 tcacttcagg agtgattaca tgaacaaaaa tataaaatat tctcaaaact ttttaacgag
     1501 tgaaaaagta ctcaaccaaa taataaaaca attgaattta aaagaaaccg ataccgttta
     1561 cgaaattgga acaggtaaag ggcatttaac gacgaaactg gctaaaataa gtaaacaggt
     1621 aacgtctatt gaattagaca gtcatctatt caacttatcg tcagaaaaat taaaactgaa
     1681 cattcgtgtc actttaattc accaagatat tctacagttt caattcccta acaaacagag
     1741 gtataaaatt gttgggagta ttccttacca tttaagcaca caaattatta aaaaagtggt
     1801 ttttgaaagc catgcgtctg acatctatct gattgttgaa gaaggattct acaagcgtac
     1861 cttggatatt caccgaacac tagggttgct cttgcacact caagtctcga ttcagcaatt
     1921 gcttaagctg ccagcggaat gctttcatcc taaaccaaaa gtaaacagtg tcttaataaa
     1981 acttacccgc cataccacag atgttccaga taaatattgg aagctatata cgtactttgt
     2041 ttcaaaatgg gtcaatcgag aatatcgtca actgtttact aaaaatcagt ttcatcaagc
     2101 aatgaaacac gccaaagtaa acaatttaag taccgttact tatgagcaag tattgtctat
     2161 ttttaatagt tatctattat ttaacgggag gaaataattc tatgagtcgc ttttttaaat
     2221 ttggaaagtt acacgttact aaagggaatg gagataaatt attagatata ctactgacag
     2281 cttccaagaa gctaaagagg tccctagcgc ctacggggaa tttgtatcga taaggggtac
     2341 aaattcccac taagcgctcg ggaccccttg taggaaaatg tcctaagtgt ggcaacaata
     2401 ttgtattaaa aaaatcgttt tatggttgtt caaattatcc tgaatgtaag tttactttag
     2461 ctgaacattt tagaaagaaa aaactaacca aaacgaatgt aaaagaatta ctggagggaa
     2521 aagaaaccct ggtaaaagga atcaaaaaca aagagaaaaa gccctacaat gccgttgtaa
     2581 aaattgggga aaagggatat attgatttta tctctttttc aaaataaaca taaaagccct
     2641 ttaaagaggg cttttatata ttaatcacaa atcacttatc acaaatcaca agtgattaat
     2701 cacttgttta ttaagatatt aaaagctata atttaaataa agcgtgaatt ttatgacaca
     2761 aaaagagggg ggagaaactt ggaactagca tttagagaaa gcttaaaaaa gatgagaggt
     2821 accaaatcaa aagaaaaatt ctcccaagaa ttagaaatga gtagatcaaa ttattcacga
     2881 atagaatcag gaaaatcaga tccaaccata aaaacactag aacaaattgc aaagttaact
     2941 aactcaacgc tagtagtgga tttaatccca aatgagccaa cagaaccaga accagaaaca
     3001 gaacaagtaa cattggagtt agaaatggaa gaagaaaaaa gcaatgattt cgtgtgaata
     3061 atgcacgaaa tcattgctta tttttttaaa aagcgatata ctagatataa cgaaacaacg
     3121 aactgaataa agaatacaaa aaaagagcca cgaccagtta aagcctgaga aactttaact
     3181 gcgagcctta attgattacc accaatcaat taaagaagtc gagacccaaa atttggtaaa
     3241 gtatttaatt actttattaa tcagatactt aaatatttgt aaacccatta tatcgggttt
     3301 ttgaggggat ttcaagtctt taagaagata ccaggcaatc aattaagaaa aacttagttg
     3361 attgcctttt ttgttgtgat tcaactttga tcgtagcttc taactaatta attttcgtaa
     3421 gaaaggagaa cagctgaatg aatatccctt ttgttgtaga aactgtgctt catgacggct
     3481 tgttaaagta caaatttaaa aatagtaaaa ttcgctcaat cactaccaag ccaggtaaaa
     3541 gtaaaggggc tatttttgcg tatcgctcaa aaaaaagcat gattggcgga cgtggcgttg
     3601 ttctgacttc cgaagaagcg attcacgaaa atcaagatac atttacgcat tggacaccaa
     3661 acgtttatcg ttatggtacg tatgcagacg aaaaccgttc atacactaaa ggacattctg
     3721 aaaacaattt aagacaaatc aataccttct ttattgattt tgatattcac acggaaaaag
     3781 aaactatttc agcaagcgat attttaacaa cagctattga tttaggtttt atgcctacgt
     3841 taattatcaa atctgataaa ggttatcaag catattttgt tttagaaacg ccagtctatg
     3901 tgacttcaaa atcagaattt aaatctgtca aagcagccaa aataatctcg caaaatatcc
     3961 gagaatattt tggaaagtct ttgccagttg atctaacgtg caatcatttt gggattgctc
     4021 gtataccaag aacggacaat gtagaatttt ttgatcccaa ttaccgttat tctttcaaag
     4081 aatggcaaga ttggtctttc aaacaaacag ataataaggg ctttactcgt tcaagtctaa
     4141 cggttttaag cggtacagaa ggcaaaaaac aagtagatga accctggttt aatctcttat
     4201 tgcacgaaac gaaattttca ggagaaaagg gtttagtagg gcgcaatagc gttatgttta
     4261 ccctctcttt agcctacttt agttcaggct attcaatcga aacgtgcgaa tataatatgt
     4321 ttgagtttaa aaacatttta aaatactaat tagattagtt aaatgactat ttgaaatagt
     4381 attttgagga gtgattatat gtgtacaaga tttgtttaca atggtataga taaaattgtt
     4441 ggttttaatt ttgatattga cctttctgta tgggatcata ctgtaattac cgaagaaaat
     4501 agattttata ttggtattaa aatgcctgac ggtctgtatc attcatttca tgggataaat
     4561 aaaaatggta atgtaggaac acttctttat gttcatggta atgaaaatgc aaggtatata
     4621 gaaagcgagg attgtattac aatatctgaa ttaacagaaa aattcattaa ggcagagatt
     4681 tcttttgata aagccttgga cattgttaaa aagaaaaaaa ttatttatgc accagatgct
     4741 actatgcaag ctatgctttc tgataaaaaa ggacgagttt taattattga acctggaatt
     4801 gggtatagat atgaacaaga aaatttttca cttattacaa attattctat tctaaaacca
     4861 gatataacaa agccgtacat tgtttctggg gatacaagat acgaagtggc taaagagtta
     4921 ttggcaggat atgataaaga tttttcagta aatgacgcat ttaaagtatt aaaatctgtt
     4981 tctcaaaaag acttgtgggc aactagggtt tcatttgtat attctacaga aaaaaataaa
     5041 gtttattatg tcttgaacaa tgattttagt aatgtatttg aatttcagtt ttaatactaa
     5101 tgaatttata aatttgcaat tatgataaga aaggttatta tgataggact aaaaaagcga
     5161 gatataaaaa aagcgttgaa agctggtgca aaagctggcg gtgtatcatt ggctgatgtt
     5221 cgggcagata ttgaagcgac gattgatgaa gctatgaata gcaccgcccc agaagtgtag
     5281 gcaaatttca aaaaatattt tggtaataaa cgccctaccc cagaagaata tatttacaag
     5341 attaccaaaa agacaaagat ttgaaaaaag gcttgctcca tacatagtgt atgatctgca
     5401 agccttaatc tatttcagag gaaatttaac agtaaaagta gcacctccac cagcagtatc
     5461 attgataatg ataataccgt tcagcatttg agttaattct ttggcgatac ttagtcccag
     5521 tccaaaattc gatttgttcg tatgggactt gtcgccacta taaaatcggt caaagatata
     5581 ctgcttatct tcatcagaaa tgccttgccc gtggtctacc acagaaaaag caatattttt
     5641 ttcggtggcg attacttcta tctctattaa agaattattc ttggaatgtt gaatggcatt
     5701 atccataaag acacacaaga tttgaaataa tcggtctttg tcggtaaaca tagcaggata
     5761 actttcctcg gataaatgca gttttagttc taaattctgc ttcatgcaga cgggttcgta
     5821 ggtttcatat aacgtaatga gcaaggtatc tacattgatt gtgcttttat gcaatgtcca
     5881 tgttttagcg tcggaagaag ccaaaagcaa catatctttg actaaacggg ataaccgcat
     5941 acattcaaaa tctatggtct gtacggcttg ctttgcctgc tcgtttaagg aaacattatc
     6001 aagaagcata tccgtgttgg aaatcataac agcaagtgga gattttaatt catgggacgc
     6061 tgttgcaaca aaatcttttt ggctttgcag tattcgttcc gttggagcaa acgacttttt
     6121 cagcagataa cgggtcagca cgataacaac gatacaagcc aaaaaccaga taagaagata
     6181 tataggcaat gttttttgta aaatatccgt caaactggct gtctgataaa gaaaggttgc
     6241 atgatacacg gtatcatttg ctgtcctaat tgtagcagga ataacaaaat aagtatcgtg
     6301 atgtgttcct cttatttcca gaaaaccgcc ttgtgaagtt gtgctgtttt ctatttgtga
     6361 taatggttgt gtagaaatct gcttttctac atcatgcaac agattgtccg cagaagttgg
     6421 aaatgggaaa tcactctgat aaatggtatt cccccttgta tcagtaatta aagaaaaaat
     6481 atgataactc tcttcgtagg ttttgagtgc tttgtccata tccgaagaag cactttccac
     6541 ttgataaatc agcaaggttg tcaatctctg aaataaggtg ctttcgttga ttttctctgt
     6601 atgaactgtg ttcgcaacga caaaggaaat cacaagggta ataatcagca taacagaact
     6661 tgcaaacaga atatgaagtt ttcggtataa gttatttaac atgtttcttt ctccagtttg
     6721 taccctgcac cgtagaccgt tgttatttta caggaacttt ttaattcttt taggcgtttt
     6781 cgcagaaaag aaatgtaact gtctacattg ccagtttcta cctcggaaga actgccccag
     6841 attttaagga ttagctgttc acgggaaaat agtgtttctg ggttctgcat aaatacaaaa
     6901 gtcaactcgg tttcttttga agttaataaa agagaattga cgggtgtaga taaggttcgg
     6961 ctgtctttat cgaaagttaa atctccatat tctaatttgg aagataactg gatattggca
     7021 gggcgtcttg ttaatgcccg aactcttgca agcaattctt tgatatgaaa tggttttact
     7081 aaataatcat cagcaccgcc gtctaaaccc tcaacccgat tgtcaagggt actcatggca
     7141 gtaatgataa ggataggaat agaaattcct tttttacgca tagattttat gattgtcaaa
     7201 ccgtcaataa tcggtaacat acggtctaca atggcgaggt cataagcata gtctgtattt
     7261 aaggcataca gcatagcagt ttccccgtca ttgcaacaat caaccatata gttttctttt
     7321 tccagcgaaa tttttatatt tttacataac tctaaatcat cttccagaag aagtattttc
     7381 ataatgtatc aatccttttc tatatatcat cttggacatt agcagtccaa gaagctttaa
     7441 ttatagacag tataacagaa aagtctgtaa aaatcctcta aaaaatgatg atgattttct
     7501 tgctttttta caggattttt agaatggttt gcttttacaa tagtggcata tcgaataaga
     7561 aaggtggaat acaaaatgaa aaaaacaaac atcagtaaat ttgtagcagt tggattatgt
     7621 atctgtgcat tgacggggtg tggtgcaagt ccagatgaga agccagatat gtctaatcct
     7681 attgtcaatt ctaatacgaa tgaagaaaat gcaaatggct cttcagaaaa taaagaaaac
     7741 gacatattag agtctgctaa tttgatagga agtgttttgg aatttacaga caatggttgt
     7801 tccgtaagtc aagcaaaaga aattgagggg ggagcaggga taaaatcaga agcaccggga
     7861 ctggaaaata aagacaatgc tgtttctgta acctataacc cagattgtga atttgtcatt
     7921 gccacagtaa atgcacagtc tggtgttaca aatgtaacaa cgggttctat atccgatgta
     7981 aaaaaacaat ctgaagtata tctttatgga gaatttgcag acacacttca tttcaatgca
     8041 acaaaggttg tcatagcccg ttgggaatag aggtgtgaag tatgaagttt tatcaacttg
     8101 gttttcgcta tttacagcga aaaaaaggaa aaaccattct tttgttgatt gttttgatac
     8161 ttgtaaacag tatgatttta ggtacaagca tgattttaag gactacaaat gagtccaaac
     8221 aagccatgca ggaaaagaca aattctaaga ttgtagctga aattacaagt aaggacagca
     8281 agataacaga gaatgaagta aacaagattg aaacgctgga agatgtttca gctatcaacc
     8341 gtatcggcag gcaagatgta tttccagcta gttttgctcc cgttacgctc aatacttcta
     8401 cgaatgagga aaatttgaaa atagcactgc tttcctatga tgatttggaa aaggacagcc
     8461 ctttttcaga aatgcagtac cgcttagctt ctggcgatta tatcaagcgt gagaaaaagg
     8521 gtgctgttat caatgcgaac cttgcaaatc aaaatgagct aaaagttgga gatacgattg
     8581 aattaagtac agaaaacgga acaaaagtat ctgttcagat tattggaatt ttcatgtccg
     8641 caggaaatgc ggaaaaagac cagccgtcag aaactaccgc agtcaatcga atagaaaatc
     8701 aaatctttat tgacaacagt acttataaag aattgttcaa agaagctgaa tttgaaaaaa
     8761 tctgcattta ctcaaaaaga ccagaaaaat tagatgtgct ggaaaccagc ctgcaaaaaa
     8821 tattcggaaa tgatgtagca cttagcacgt ctgataccct ttatcaacag atgtctgctc
     8881 cattagagca aatcagtaag gtggcaaatc ttatgctggt acttacattg gtaactggta
     8941 ctgttgttgt ttccctgctg ttatgtatgt ggatgcggac aaggcaaaaa gaggtggcaa
     9001 tctttatgag cctcggcaag acaaaaagtg aaattttcct gcaaacttta ttagaagcag
     9061 gcagtgtatt tacactttcg gttttaggag caacagccat tggtaaattg ttctcgggcg
     9121 ttttgcaaaa cgtcattacc ggttcagaaa cagtaacaga aaatctgaaa gtggttttgc
     9181 agatacaaga tattggaatg ttgttccttt taggcggtgc agttattttg gtggcattgt
     9241 gctgttccat tcttccgata ttacgagcaa acccaaaaga tatattagca aaaatggagg
     9301 gatagtacat gaattttttt ggattggcaa ggcgttctgt gttcagaaag cccgtaaaaa
     9361 gtattctctt attgttgatt gtttttgcaa tcagtacctt gcttcttgca ggtgtggcga
     9421 gcaaaaatgc cagtattgag gtgcaggaca aaaccagaca agccataggt gcaggctttc
     9481 ttttagaaag aaatgcagag taccgaacaa agcgagttcg tgaatactca gaaaagattg
     9541 gtaatgataa ggaaggtagt tttggtggct accatcagga aaaagagatt atcaatggtg
     9601 tggagacttg gacaggctgg acaacaaatg aatttgaaag cttagatata aaagacattg
     9661 agaaattggc aaaagcaaaa ggaattgctg attacaatat tacaacagta acaactcccg
     9721 taaaccctgt aaatttcaaa aggattgaag ataaagatgt agaccagaat gcagatgttg
     9781 gcggtgtaag tttaattgga aacaaagata tgaaactaga cagaaatgtt ttatctggaa
     9841 acctgcatat caaagaggga cgaatgataa ccccagagga taaagatatg tgtgtcattt
     9901 cagaggaact ggcaaagcaa aataatctga aaatcggcga taagatttct tttaatgatt
     9961 accacgatac tgaaaattca aaggtatcag aagctgagat tgttggaatt tatcaagtgg
    10021 atcaaaagat gtccccactt atgcagggag atacttaccg ttcggaaaat gtaatattta
    10081 cagatttgag atttccagaa aaggcagagg gtgaaacaag tccattatat gaaagagcct
    10141 atttcaaagt ggaagatgtg gaagcttacg acgaagtaaa agaaaatctg caaaaagtag
    10201 acatcaattg ggagcaatat gatttgattg acaataacgg aaattccgaa accatgtcct
    10261 caaacttcaa tgatttagca aaagtaagcg aaatgatgat attggtaatc tctgttgcaa
    10321 gttttgttat ccttgtttta gtatttctgt tctggctgaa aaatcgagtg caggaagtcg
    10381 gtattttctt atctctcggt gttccgaaat ttagaattat cggacaaatt tggagcgaag
    10441 cgattatgat tactgttctt tcccttatgt tatcctttgc tgtcgctcct gctgtttcca
    10501 aagtaacggc aaattatctg gtatcacagc aggttcagca aatgcaagag gaagaaaaga
    10561 ataatgaggg aaaagtatcc acagaatacg ttgcaccaaa gcaggacgtg cagagtatca
    10621 gcgtagaggt tacaccagaa atgtatctgt tggacggtgt aagtgttctt gtgttgataa
    10681 cggcttctgt tctggtatct ggaattgtaa tactaaagag aaacccgaaa gatattttat
    10741 cggaaatgag ttaggaggac gacgaaaatg ttagaagtaa agaatgtaag ctatgcttac
    10801 aaaacaaaaa aagataaaac cattttgaat aatgtatctg ctactttcga ggagggtatc
    10861 ttttatacca ttatcggtcc gagtggtgca ggaaaaacaa cactcttatc gttgttagca
    10921 ggcttagata cagcagtaaa agggactgtc ctttgcaatg gcgaggatat tacaaaaaaa
    10981 gggctgaatt accacagaaa gcataatatc tcattggtat ttcaaaatta taatctgatt
    11041 gattatttga caacggttga aaatgtcaaa ttaggtggta gtggaaatgc tgaaaaatta
    11101 ttggaagaag tcggtattgg aaaagaatac tggcagagaa atgtattgca actatctggc
    11161 ggacagcaac agcgtgtagc gattgcaaga gcattagcca gcgacgctca tgtacttttg
    11221 gcagatgaac cgacgggaaa tcttgatgaa actaccgctg atgaaatcat tgctttgctg
    11281 aaaaagactg cacatgaatt aggaaaatgt gttgttgtgg ttacacacag taagcatttg
    11341 gcagaagaag ccgacgaaat cttagaaatt aaaaacggtg caatttcttt tctgtctgaa
    11401 taaacaagaa tagtgccgta aaggagctgt cattatggaa tattttagat atacctcgac
    11461 acaatcaatt tgaccctaac ggcattgtta taagaactaa atacaataca gtttcaaagg
    11521 ctcgtacaga ctatatgttt tgtgcgggct tttttcatgc cagaaaaaaa ttttttaagt
    11581 tttttttgat tttggttacg ctgtacccca ctttcaacgc ggtatatatg aaaaggggca
    11641 gacacctctt ttcgactagc gaaaggaggt gaggaaaata aaaccgtcag aactacaaga
    11701 aaaaacctgt catcaattcg attgtgctat taaaacagtt atacgtcata gagcgattga
    11761 cttctatcga gcgatacgtc gttcagagaa aaaagaaatg ccattcgccg aaattatgga
    11821 cgacctctta aattccatag gcacagaaga tacatattct acggattatg ttgcagtatt
    11881 tgaagtctgt ggcgaaaaag tgtcaatcga agatgaacaa ctggctcgtg cattgaaagc
    11941 tattgaagaa cgaaagcgta atatcgtttt acagtatttt ttcattgggg acacggacac
    12001 ttatattgga aaaatgcttg actgttccag agctaatgta acaaaatgca gaatacaagc
    12061 actcgacaag ctaaagcaac tgattgagga ggaaaaagag aaatgccaaa agagctgaca
    12121 ccgactttca cggttatttc caaagcatgc gacggcgacg aaacagctat ttcaaaaatc
    12181 ttggagtttt acgacccatt tatcaatcag tgctgtatgc gtccgtttta cgatgataac
    12241 aacaacttgc gtcttgcggt agatttggaa atgaaaggtt ttatcaaaga agcgattatt
    12301 cgtaaaatct taaactttga tattaaacgc ttctaattca tatcgggatt gattatgccc
    12361 gtctggtctt tgacaactga ataaagcaga cagatacgtt tgtgagatag caagccacgg
    12421 ggactgtacg ccatgacctt tccaaaagaa agcgagcgac ccatgcagtg atccgagagc
    12481 gaccgttgga aaagtcgctt tgccacgacc tatcctcaca gaataatgat acgtccgcat
    12541 ggtgcggttc tgccc
//
LOCUS       DAEPXW010000273        11269 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain J69
            SAMN13376431-rid12479243.guided.116, whole genome shotgun sequence.
ACCESSION   DAEPXW010000273 DAEPXW010000000
VERSION     DAEPXW010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376431
            Sequence Read Archive: SRR10518407
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069599.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069599.1
            Genome Coverage       :: 320x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:45:27
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,878
            CDSs (total)                      :: 3,791
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 24 of 54
            Pseudo Genes (incomplete)         :: 25 of 54
            Pseudo Genes (internal stop)      :: 15 of 54
            Pseudo Genes (multiple problems)  :: 9 of 54
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11269
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376431-rid12479243.guided.116"
                     /strain="J69"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="China: Huzhou"
                     /collection_date="2017"
     gene            415..753
                     /locus_tag="KRM55_003864"
     CDS             415..753
                     /locus_tag="KRM55_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1596003.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            775..1092
                     /locus_tag="KRM55_003865"
     CDS             775..1092
                     /locus_tag="KRM55_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1596004.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1242..1919
                     /locus_tag="KRM55_003866"
     CDS             1242..1919
                     /locus_tag="KRM55_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1596005.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2247..3014)
                     /locus_tag="KRM55_003867"
     CDS             complement(2247..3014)
                     /locus_tag="KRM55_003867"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBH1596006.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3686..4501)
                     /locus_tag="KRM55_003868"
     CDS             complement(3686..4501)
                     /locus_tag="KRM55_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBH1596007.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            4602..5300
                     /locus_tag="KRM55_003869"
     CDS             4602..5300
                     /locus_tag="KRM55_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1596008.1"
                     /translation="MYKLSYVVRVSTKDLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKSSITNALASAFIGSLGGGKLFSNNMLVYYVVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKNDSESLAIDILTFLAGISSRDSD
                     KFLQKNDNWKIIME"
     gene            5388..6008
                     /locus_tag="KRM55_003870"
     CDS             5388..6008
                     /locus_tag="KRM55_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1596009.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLISYENKRFSVINQREVLKNLPTT"
     gene            6164..6946
                     /locus_tag="KRM55_003871"
     CDS             6164..6946
                     /locus_tag="KRM55_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBH1596010.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLASLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            7071..7997
                     /locus_tag="KRM55_003872"
     CDS             7071..7997
                     /locus_tag="KRM55_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1596011.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            8011..8460
                     /locus_tag="KRM55_003873"
                     /pseudo
     CDS             8011..8460
                     /locus_tag="KRM55_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8819..9226
                     /locus_tag="KRM55_003874"
     CDS             8819..9226
                     /locus_tag="KRM55_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1596012.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRINDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKKLKELMEEH"
     gene            9228..9458
                     /locus_tag="KRM55_003875"
     CDS             9228..9458
                     /locus_tag="KRM55_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1596013.1"
                     /translation="MKPTKEVLPFTIILLAVHSDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            9848..10051
                     /locus_tag="KRM55_003876"
     CDS             9848..10051
                     /locus_tag="KRM55_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1596014.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            10129..10482
                     /locus_tag="KRM55_003877"
     CDS             10129..10482
                     /locus_tag="KRM55_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH1596015.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            10554..11186
                     /locus_tag="KRM55_003878"
     CDS             10554..11186
                     /locus_tag="KRM55_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH1596016.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         4165 a         1583 c         1750 g         3771 t
ORIGIN      
        1 atatataatt agatttaaaa aagtttacct taccaatata atgattaaac tcaaaagtct
       61 tattgaaaaa ttttctattt acataaattg ttcaatatat aaaatagaaa atttttttaa
      121 ttttcaaaat atattctaca tatctaatat gtaattacaa taaaaaatgc tataattaac
      181 atattattaa ttcgttttat tattgtagta tggctatgaa attatgaaaa tatttctcta
      241 attaaaaata tgatttatcc atatttgttt attgtagata cagactatac aaaaataaat
      301 agcacttatt tcagtataaa aacatatata gtctatattt agactaaaaa agtataaata
      361 gtctatataa aacaacttaa actatgaata taatctaaag tggagggata ataattggca
      421 aatataggaa aaataatagg agatagaata aaagtctata gaacaaaatt gggatatagt
      481 caagagtttc tagcagaaaa ggcaggttta catccaacat atattggtca gattgaaaga
      541 gctgagacaa atacatctat caatattata atgaaaattg ctactgcttt agacatacca
      601 cttgaattgt tatttgcaaa tattattaca acagaaggcg ttgataactc tgtaccttta
      661 gaatgttatg aaatgattaa taaattaact gaaaaagaac aaattgcaat gctagagtta
      721 ataaagtgca tcattaaata caaagaaata taagtgaggg aaatagtaac aataatgaat
      781 tatataggta aaagacttaa agaagaacgg aaaaaagcaa atttaacttc aaaagaattt
      841 gcaaatatgg ttggagtatc gccttggtat ataactcaaa tcgaaagtgg taaaaagaat
      901 ccaagtctta aaacattcat aaaatttgta aatatattaa atatttctgc agatgttctt
      961 ataaaagata ttacttccac tggaaaaaca tatttagaaa atgatataaa tgaagagtta
     1021 aaagacttaa attcaagaga actaaatctg atatcacaga ttatagacat cataaaaaag
     1081 aataaaatat aattctttat attttatata aaaaaaaagg ttatttgaaa taaataacct
     1141 ttttttgtct ttttgtgtta acattgtctt atagtgctaa tgagtactat tagaccatgt
     1201 tctatggcct tattttaata taaaacgatt ggagataggc tatgattgtg attgaaggta
     1261 gcgataaatt taagattgca aaagaatata ttgatgtaga atatactctt tttagcaaag
     1321 taacttttag gtatgaaaag ttgaaattta aagataatgc tgaattggaa aaaattaaga
     1381 tgtttaaata taaaaatggc tacatcccta ataaattaaa cctttctttt ggatatggat
     1441 tctcttctta taaaaagcaa ataattagag aaactgtaga tactttaaga ttgacagaaa
     1501 ttttttcaag cgagaacata gaagatatta aatttataaa agatggtaca aaaaaattag
     1561 aaattagcat agagaaagtt gtgaaattta aacgtcgaaa aaaaagaaat tatgtttgtt
     1621 gctattgccc tgatatgtat agggacataa aactcgacaa agaatctatc aataagatat
     1681 acaacagaaa aataaaaata gaaagagaag ttaatatttt tgaagatgag gatgttataa
     1741 taaacaaaaa agtattgaag tttccaaagt cttggacaaa gaatatgcaa aaatattggt
     1801 taagtgaaaa taagtatccc atacattcta ctgtaattga tgatgataga tataaatgtt
     1861 gtaatgtaca atatacaaaa aatagagtga taatattata ttacatatat aaccattaat
     1921 atacataatt acaaaaaaat aatgacaaat atacataata caaatatatc ttctacttta
     1981 gataaaacag ttattatgaa aacttactat ctataaataa tagaaatgct agtataccat
     2041 ctataatcta atgtctagta ggttttaatg gcatatttta aatatgccat agttgattta
     2101 taaggttttc tatatcactt tcaaaataca cactaaatag ttgcttttca gatataattg
     2161 cccaatttaa attttactat ctgaaaagtt ttttatattt aatttatatc ttcaaaaata
     2221 ccgtctaata tttctatata attaatttaa ttaatactct tatgtaatag attaagtact
     2281 gaatttaact ctttaaatga tatttgccct ggtgctgaaa cactttttgc agctccaaaa
     2341 gtcaatgcag aaccaaatat ttcaccacac aatctactta taacacccat tcctgacatt
     2401 gacattgtta ttattggtct atctgcataa attttaaaca tttcatttgt agcttcaagt
     2461 agcactaaca catctttttc attttgcggc ataacagcta ttttaggtaa atctgcgccc
     2521 aattcctgca ttctacataa acgagataca atctcttctt tttttggagt tttattaaaa
     2581 tcatgattag atataattac tttcacttct tttttatgag caaaattaac tacttcatct
     2641 atgacctcat ctcccataaa taactctaca tctattaaat ctactaaacc tgtattagaa
     2701 atttctttat tcaaagtagt ataataatct cttgatatta atttttctcc cccttctact
     2761 acacttctaa atgtgaataa taaagggata tcatgtatat aacttcttaa ttcatagaga
     2821 acttccttaa cttctttaat attttctaca ttctcaaaaa aatcaactcg ccactctata
     2881 atatccaaac atgcatcttt taactcttta gcctctttta taatatcttt tttatttttc
     2941 ccaataattg gtacacaaat tttaggtcta ccttctccaa tagtaatatt ttttacttga
     3001 acttttcttt tcatattctc ctccataatc agaaattcta taggacttta aattctattt
     3061 tctgcacaat ttaattatac attaaaaata ctatacatta taaaaatact aatttaaaaa
     3121 taatttttat tctaattctt aaaacaatcc cacatatttt agaaaaggta ctctataata
     3181 tacaaacact tcttttttac ctaaatttat tttaacatcc tataattttc acaatattct
     3241 ttaaatttta ctcatataaa caatattatt ctggatgcta atagaattaa tctataaatc
     3301 atagtataat tatgcagaaa taactcgaat ttcactactt atgaagagat tgaatattaa
     3361 tgaatctaag tcatttgcat tacttaagag ttttgactaa agttgaacac catacaaaag
     3421 tagctactca attgtttata ccccaaccaa gcttaagtaa tgttatatag attctcgaaa
     3481 aagaatttgg tatcttttta tttgaaaaac ttatattaaa tttgattatc ttttcataag
     3541 ttggtaaatg tcgatatatc ctgtatctac aaggagtatc ggcattttct ttttggaaga
     3601 tactttgcat aagttggcat ttaaccgtat aagaatgcca tcaaaagtag taaataagta
     3661 gtaaactcta gtcatactac taggattata accgctccat ttcagctctc gaagaactaa
     3721 atgaaccatg tgcataatag ccaagcgtca tagtaatgtt tttatgcccc ataatatatt
     3781 gcaatatatt aggactcatt cctttgttag ccatatttgt acagagtgta tgcctaaagg
     3841 tatgtggcgt aatctttggt agcttgtcct catgggtctt attatacttc ttgactaacg
     3901 ctcttaacat gctttgataa tgagttgctt gttttggtaa tccatcttgt ttaagaaata
     3961 ggaagttctg gtaaccatca acaatgattg gttctgcttt agcgttctta cgccgttcca
     4021 cgatacgttc aaatgattga taagctcttt cagtcattgg aatttctcgc ttaccctgtg
     4081 tggtctttgg aacttctaca taatagccaa tcttagtatc actcaacaat tgatggtcta
     4141 ccataatggc tttatttttc atatccaatt ctaaagtcaa accgcataat tcagaaatgc
     4201 gtagtcctgt ttctaagagg ataacaacat catcataata tttacaataa gtcttatcgc
     4261 tctccataaa ggataataag cccatttcct gttctggtgt tagagcgatt tttggttctg
     4321 ttgtatcttc caaaacatca cttaactgaa aattaaatgg attctttcta atacagtcgt
     4381 cttgaattgc catgaaaaac gacgctttca gtgagcgctt ataattgtca atggatttat
     4441 aagcacaccc atcttcactc attcggatag cccagctttt agcgtctgat aatttaacca
     4501 tatcaatgct ttttgcacct agtgggtcat tgatagtatc tatattttga tttataattt
     4561 atacattttt ttaaaaacag acttttaact gtaaagaatc tatgtataaa cttagctatg
     4621 ttgtccgtgt atctacaaag gatcttgacg agctaaaaag gcgttgtgat gaagtcaaag
     4681 acttttacga cgacttatca atcaagctcg tgcgtccctt tggggatatg ttaggattgc
     4741 atggcgaatt tattcctgtc agcaaacgtt acatcaatga ttatattcaa tatgtcactt
     4801 cggatttttt ggctggactt ggttttggag cgacacaaac ccttggcgaa catgaggata
     4861 tctatcttgg ctacaatctg gacactggaa agaatgtcta tctaaaacct gcccttgcta
     4921 gtcaaggggt aaagagttct attaccaatg cgttagcgtc tgcgtttatc ggttcattgg
     4981 gtggtggtaa attattcagt aacaatatgc ttgtttacta tgtggtacta ttcggcggac
     5041 aggcggtcat agttgaccct aaagcagaac gcggcaaatg gaaagaaacg ctaccagaaa
     5101 tagcccatga gataaacatt gtcaatttaa ccagtaatga tgaaaacaaa ggattgcttg
     5161 acccttacgt cattttgagc cgtaaaaatg attctgaaag tttagcgatt gatatcctaa
     5221 cattccttgc tggtatctcc agtcgtgaca gtgataagtt tttgcagaaa aatgacaact
     5281 ggaaaataat aatggaatag tttctatgta aatatatttt tactatctta cctaactaat
     5341 tgaaagatga tataatttaa tcaaagattt ggtaaggagg gatgaatatg catttaattg
     5401 attttatgaa tgaagatatt aaaaagaagc ttgttaaaaa aacgtataaa aagaaagaga
     5461 ctattctttt tgctgagcaa gaaaatgaat atgtaattct tatgattgac ggtattgcag
     5521 aagcattcat cttaaatgtg aaaggaaaca tctcaacgat tcatctttat agaagtggta
     5581 gtttttttgg agaaatggaa caatttaatg atgggaaaaa acccgttgaa attgtcgctt
     5641 tcacagattg taatgtatat aaacttcata gagatgattt tttaaactgg ttaaggggag
     5701 attttgaagc tacaaaattt ctgattcgag aaatatctag taaattagtt gtaaatgctg
     5761 aattaattga agaattatca tctttaagtg ttaaagaacg acttctgagg tgtatatcct
     5821 tacactatta tagaagtgaa ttaaatctgc ttaccaaaaa acagcttgct agcgaagtaa
     5881 acgctccaat tagaagcatt aatcgtgcta taaatgaatg tgtacaagaa catctaattt
     5941 cttatgaaaa caaaagattt agtgtaatta atcagcgaga ggtattaaag aatcttccta
     6001 caacataagt ataatttcaa aaaagtattg aataataatt attcaatgct tttttatttc
     6061 gggtcaagtg acctattttt ttttatttct tcattatata atactcctat gcataattat
     6121 gttggattga tagctaataa aagacagtga gaggtgttat attatgacta aaacacaaca
     6181 gaaaatgata caaaacgtat tagaattttc aaaaagagat agtaggataa taggacttgc
     6241 aattagcggt tcttatatca caaaatcgtt agatgaatat tctgatttgg attttctgat
     6301 tgtagcagat gataaatcct atgaagaagt tatcgaagag agattactta ttgtggaaca
     6361 gtttggaaca ttagtttctg cttttactgg cgaacatgtt ggagaacctc gattgataat
     6421 ttccctctat gattcccctg ttcttcatgt tgattttaag tttacaacct tagatggttt
     6481 actagatagg gttgaagatt cagctattct ctatgaagaa aacaactgca taacagaaat
     6541 ttattctaaa aaagaagcat acttcccaac tccagactta cagtggattg aagatagatt
     6601 ttggatttgg gttcattacg cttgcactaa gattggacgt agagaactat ttgaaacaat
     6661 tgatttttta tcttttttaa gacaatcagt acttgcctcg ttaatacagc ttctcttagg
     6721 taaattacct cgtggagtta gaaaaattga attggacgca ccccaatata ttgaagcatt
     6781 agaaaagacg gttgctaacc atgaatataa aagctgtgtt aatgcattgc aggctactat
     6841 caacctgtat cttgagttaa gagaggaatt atcacaaagt cctattgtcc gaaaggttga
     6901 agctgaaagg gttgcattac agtattttca agatttaatc aaataaaccc aaagtaaaaa
     6961 aatattgaat agtaaatatt cagtgttttt tcatttttgg tcaaatgacc tagattagtt
     7021 gttgtaacaa ttctataatt attttgaaag taacagtatg gaggataact atgagtgata
     7081 ttttaagtag aattacaaat aaaattgggg ataagaatat agttgataag ttatcagctc
     7141 tatcaaaatc agatttgaac tcacttctat tagaagtgtt tgatagacaa gcaaatactt
     7201 taactgcaac tgatattcta aagtcatacc aactaaatag atttactatc cctagcggta
     7261 tagatccaga agaaattcat gctttggagt caaaattatt gagaaaagca ttcaatatgg
     7321 atatcaagac gattatgctt tctccctctg ctccattagg tagctgtagc gtttttggct
     7381 ccgtagatca atataatgta gtaagtgctc tacgagggac agaaacactt gcagacccct
     7441 caaatatgtt ggcaataatt attgctgata aattaaaaag aaaagaagaa aataatacca
     7501 tacctatcca catggctact actgctaggg taataagagc acaaaatttt gtaggtaaag
     7561 gtttatattc acattttggc ttatattgta tggtttcatc tggtatagat acagggtctt
     7621 acacttgtga aaaaatgttg ttagaaaagc acttaaacta ttataaagat atattaagtg
     7681 aaatagaaaa tgttcgtttc tctattattc tacgcaaaag aaacggatac aaagataatg
     7741 acggattttt cgacagaatg gttgaaacta tcaaacttat ttttcctaat atagagttat
     7801 caattcataa tgatgatgtt gataataatt attataaagg tatcaatttc aaattatcgg
     7861 tcaaacaagg aaatgaaacc gttgaaatag ttgacggtgg atttgttgac tggacttatc
     7921 aaatgcttgg aaataaaaaa gaacgctgtt tgataagtgg tattggctta gaaagatttc
     7981 ttgtagctgt ttcataaaag gagaagaaaa atggaactta tagagtggaa ttatgcttat
     8041 attaccgatt tagttgagtt tgcgaatgat aaagaaattg caaagaatct tcgtgacaac
     8101 ttcccccacc cttataggga gcaaaacgct agagatttta ttagtttttg tttggcaact
     8161 ccagatgtta aacaacttag ctatgctatt ttttatcaag aaagggctat tggaagtatc
     8221 agcctaacat ttgaagaaga tacctctatt aataaaaatg ctgaattagg ttactggctt
     8281 gctaggaact attggggcaa agggatagca acaaatgcag taaaagaaat atgcaaaatt
     8341 gcctttgaaa aataaaacct taacaaaatt catgctaatg tatattccta caatagaggg
     8401 tcaagtaaag tattggaaaa atgtggtttt aagattgaag aatactgtca caattcataa
     8461 taaagaatag aaacatgatt gattgccatg tatatagttt aattcaaccg caatagcatt
     8521 tattagaatt aacctacttt ttaataacag aataagtttt tcccctctat taatttctta
     8581 tgcatctttg tatttttatg aaaagctagc caatgcatat ttccatacat caatatggtg
     8641 gtggcttaca accaatataa attaaatacg ttttaaagaa tacacatttt tgccctatag
     8701 gcagagtgtg tatttttttc tctttttttg aaatttatcg aagatttaac gccctcccac
     8761 cgtgatagga gtaagcaagg ttatttaact ccttgcgatg gaaagagggt gaaatcttat
     8821 ggttgatgaa aagacaattg aacatcaatt cgacagtttc tgtaaaacag ttttgcgtaa
     8881 ctatgctaga gatatttatg acgaaaataa acgcataaat gattatttgg tatctctcga
     8941 atctttgtca cttgcagaat taagtaaatt gagtatttta gatgattatg attctaacta
     9001 catctgtatg gtttcttacg actacaacat acgaattgaa gatgtattaa tggcacaagc
     9061 aatcggaaaa cttacaaaaa gaaaacaaga tataattcta ctttcattct ttctcaacat
     9121 gacaaatgct gacatagcaa cattgatgga tttagcagaa aataccatac attatcacaa
     9181 aacaaatgca ctaaaaaagt tgaaagaact catggaggaa cattgaaatg aaacctacta
     9241 aagaagtatt accttttaca attattttac ttgctgtaca tagcgatgta aatgcaataa
     9301 acggaatact taaacatttt gaacactata tcattcgtct ttcacagaaa actttatttg
     9361 atgaatacgg aaatccctat attcatgtag aagaagaaac aaagcgaatg ctaggaacaa
     9421 aactaatcac tgctattttg agatttaatt tgtcttaatc tcgccctctc tccatgtatc
     9481 aagctatttg gtacatggag aatcactaat tatttgtcta taaaagccca taagctattg
     9541 tgatttttta tagacaaatc aatgccgact gttctttgac aactgaataa agtagataga
     9601 tacgtttgtg atacagatag ccaacaaata ctatacgcca tgaccttaat caagagagct
     9661 actatatagt gatttgtgaa taacctttgg aacggttgtt ttgccgtaac ctgtaccaca
     9721 gtataatgat acacctgtat gacacggttc tgcccataag aatgggattg gttaaaatac
     9781 caatggagct taccaaagcc atctatctac ttctgaacta cgaacataga aaggagtgat
     9841 acattctatg aacaatactg atgtacctat ttgggaaaaa tataccttga cgattgaaga
     9901 agcgtcaaaa tactttcgta ttggagagaa aaaattacgt aaacttgctg atgaaaacct
     9961 tgattctggc tgggtcatta tgaatagcaa tcgcattcaa ataaagagaa aacaatttga
    10021 gaaaatcgtt gatacacttg actttatcta atgaaattga gccttatatg ttataatatt
    10081 catatgacgt atcaagctca attcggttat tgagaggagc ttcttatcat gtcaactgaa
    10141 aaaagacgag ataataaaga tagaatttta agaactggag agagccagag aaaagatgga
    10201 agatacgcat ataagtatgt atattcattt ggtaaaccac aatttgttta ctcttggaaa
    10261 cttgtaccta ctgataaacc cccaaaggga aaacgtgatg atatatcatt aagggataag
    10321 gaaaaagcaa tacaaaatga ccttgatgat agcattgaca ctattggtaa gaaaatgaca
    10381 gtttgtcagt tatacgctaa aaagaatgga ctaagaaaga atatccgact taacactaaa
    10441 aaaggacgcc attatcttat gaagattctt aacaaggagt gattctgtga agagatgtat
    10501 tgtagtagtg gaatagtcaa aaacataata tatattaaag gagagattta aatatgacta
    10561 ttccaagttc aaataaggta tatccaagaa gtaatgatta tcaaactgta tatcttaaaa
    10621 atgtaataac aagggaaaat atagaagttg gagattacac aatatataat gacttttata
    10681 atgacccaag agattttgag aaaaacaatg tattgtatca ttaccctata aacaatgata
    10741 aattaataat tggtaagttt tgctcaatag catgtaatgc aaaatttcta atgactagtg
    10801 gaaatcactc aatgaaatca aaatccacat atacttttcc catcttttat gaagaatgga
    10861 aactcgatat caaccatata acggacgctt gggacaataa gggtaacatt ataattggaa
    10921 atgatgtgtg gataggttat gattctataa ttatgtcagg tgtaaatatt ggtgatggtg
    10981 caattattgg aacaagagca gtagttacta atgacgttcc accgtattct attgttggag
    11041 gagtacctgc aaaaattata aaaaagagat ttaataatga tacaatttca aaattattag
    11101 aaattaaatg gtgggattgg ccatataaaa aaattcaatc aaacattaag catattcaat
    11161 caggaaatat tgataaatta gtttaatatt ttataattta tttatattaa actttacttt
    11221 aataatcatt ttataagagc tttttcaaaa tttgtatatt attttaata
//
